Swift essentials

CERN Document Server

Blewitt, Alex

2014-01-01

Whether you are a seasoned Objective-C developer or new to the Xcode platform, Swift Essentials will provide you with all you need to know to get started with the language. Prior experience with iOS development is not necessary, but will be helpful to get the most out of the book.

Beginning Swift games development for iOS

CERN Document Server

Goodwill, James

2015-01-01

Game apps are one of the most popular categories in the Apple iTunes App Store. Well, the introduction of the new Swift programming language will make game development even more appealing and easier to existing and future iOS app developers. In response, James Goodwill, Wesley Matlock and Apress introduce you to this book, Beginning Swift Games Development for iOS. In this book, you'll learn the fundamental elements of the new Swift language as applied to game development for iOS. In part 1, you'll start with a basic 2D game idea and build the game throughout the book introducing each Sprit

NASA's Swift Education and Public Outreach Program

Science.gov (United States)

Cominsky, L. R.; Graves, T.; Plait, P.; Silva, S.; Simonnet, A.

2004-08-01

Few astronomical objects excite students more than big explosions and black holes. Gamma Ray Bursts (GRBs) are both: powerful explosions that signal the births of black holes. NASA's Swift satellite mission, set for launch in Fall 2004, will detect hundreds of black holes over its two-year nominal mission timeline. The NASA Education and Public Outreach (E/PO) group at Sonoma State University is leading the Swift E/PO effort, using the Swift mission to engage students in science and math learning. We have partnered with the Lawrence Hall of Science to create a ``Great Explorations in Math and Science" guide entitled ``Invisible Universe: from Radio Waves to Gamma Rays," which uses GRBs to introduce students to the electromagnetic spectrum and the scale of energies in the Universe. We have also created new standards-based activities for grades 9-12 using GRBs: one activity puts the students in the place of astronomers 20 years ago, trying to sort out various types of stellar explosions that create high-energy radiation. Another mimics the use of the Interplanetary Network to let students figure out the direction to a GRB. Post-launch materials will include magazine articles about Swift and GRBs, and live updates of GRB information to the Swift E/PO website that will excite and inspire students to learn more about space science.

Swift: A gamma ray burst MIDEX

International Nuclear Information System (INIS)

Barthelmy, Scott

2001-01-01

Swift is a first of its kind multiwavelength transient observatory for gamma-ray burst astronomy. It has the optimum capabilities for the next breakthroughs in determining the origin of gamma-ray bursts and their afterglows as well as using bursts to probe the early Universe. Swift will also perform the first sensitive hard X-ray survey of the sky. The mission is being developed by an international collaboration and consists of three instruments, the Burst Alert Telescope (BAT), the X-ray Telescope (XRT), and the Ultraviolet and Optical Telescope (UVOT). The BAT, a wide-field gamma-ray detector, will detect ∼1 gamma-ray burst per day with a sensitivity 5 times that of BATSE. The sensitive narrow-field XRT and UVOT will be autonomously slewed to the burst location in 20 to 70 seconds to determine 0.3-5.0 arcsec positions and perform optical, UV, and X-ray spectrophotometry. On-board measurements of redshift will also be done for hundreds of bursts. Swift will incorporate superb, low-cost instruments using existing flight-spare hardware and designs. Strong education/public outreach and follow-up programs will help to engage the public and astronomical community. Swift has been selected by NASA for development and launch in late 2003

The Swift MIDEX Education and Public Outreach Program

Science.gov (United States)

Feigelson, E. D.; Cominsky, L. R.; Whitlock, L. A.

1999-12-01

The Swift satellite is dedicated to an understanding of gamma-ray bursts, the most powerful explosions in the Universe since the Big Bang. A multifaceted E/PO program associated with Swift is planned. Web sites will be constructed, including sophisticated interactive learning environments for combining science concepts with with exploration and critical thinking for high school students. The award-winning instructional television program "What's in the News?", produced by Penn State Public Broadcasting and reaching several million 4th-7th graders, will create a series of broadcasts on Swift and space astronomy. A teachers' curricular guide on space astronomy will be produced by UC-Berkeley's Lawrence Hall of Science as part of their highly successful GEMS guides promoting inquiry-based science education. Teacher workshops will be conducted in the Appalachian region and nationwide to testbed and disseminate these products. We may also assist the production of gamma-ray burst museum exhibits. All aspects of the program will be overseen by a Swift Education Committee and assessed by a professional educational evaluation firm. This effort will be supported by the NASA Swift MIDEX contract to Penn State.

Gamma Ray Burst Discoveries with the Swift Mission

Science.gov (United States)

Gehrels, Neil; Tueller, Jack

2007-01-01

There is a great synergy between the Swift and INTEGRAL missions. Swift provides wide-field hard x-ray monitoring and sensitive x-ray and UV/optical observations. INTEGRAL provides optical through gamma-ray coverage with emphasis on hard xray imaging and gamma-ray spectroscopy. For hard x-ray survey studies, the BAT and IBIS instruments are complementary with BAT covering the full sky every day and IBIS scanning the galactic plane. For GRBs, Swift follows up bursts detected by INTEGRAL. X-ray and optical observations give arcsecond positions and afterglow lightcurves. For IGR sources, X-ray observations identify counterparts. The joint BAT and IBIS survey data are giving the most complete picture of the hard x-ray sky ever obtained. This talk will review Swift capabilities and discuss joint observations that are taking place and planned

On the thermodynamics of the Swift-Hohenberg theory

Science.gov (United States)

Espath, L. F. R.; Sarmiento, A. F.; Dalcin, L.; Calo, V. M.

2017-11-01

We present the microbalance including the microforces, the first- and second-order microstresses for the Swift-Hohenberg equation concomitantly with their constitutive equations, which are consistent with the free-energy imbalance. We provide an explicit form for the microstress structure for a free-energy functional endowed with second-order spatial derivatives. Additionally, we generalize the Swift-Hohenberg theory via a proper constitutive process. Finally, we present one highly resolved three-dimensional numerical simulation to demonstrate the particular form of the resulting microstresses and their interactions in the evolution of the Swift-Hohenberg equation.

The 105 month Swift-BAT data release

Science.gov (United States)

Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail; Ricci, Claudio; Lien, Amy; Trakhtenbrot, Benny; NASA GSFC Swift BAT team, BAT AGN Spectroscopic Survey (BASS)

2018-01-01

We present a new catalog of hard X-ray sources detected in the first 105 months of observations with the Burst Alert Telescope (BAT) on board the Swift observatory. The 105 month Swift-BAT survey is a uniform hard X-ray all-sky survey with a sensitivity of 8.40×10-12 erg s-1 cm-2 over 90% of the sky and 7.24×10-12 erg s-1 cm-2 over 50% of the sky in the 14‑195 keV band. The Swift-BAT 105 month catalog provides 1632 (422 new detections) hard X-ray sources in the 14 ‑ 195 keV band above the 4.8σ significance level. Adding to the previously known hard X-ray sources, 34% (144/422) of the new detections are identified as Seyfert AGN in nearby galaxies (z BAT catalog, we release eight-channel spectra and monthly sampled light curves for each object in the online journal and at the Swift-BAT 105 month Web site.

The Swift GRB MIDEX Mission

International Nuclear Information System (INIS)

Gehrels, N.

2003-01-01

Swift is a first-of-its-kind multiwavelength transient observatory for gamma-ray burst astronomy. It has the optimum capabilities for the next breakthroughs in determining the origin of gamma-ray bursts and their afterglows, as well as using bursts to probe the early Universe. Swift will also perform the first sensitive hard X-ray survey of the sky. The mission is being developed by an international collaboration and consists of three instruments, the Burst Alert Telescope (BAT), the X-ray Telescope (XRT), and the Ultraviolet and Optical Telescope (UVOT). The BAT, a wide-field gamma-ray detector, will detect 3-7 gamma-ray bursts per week with a sensitivity 5 times that of BATSE. The sensitive narrow-field XRT and UVOT will be autonomously slewed to the burst location in 20 to 70 seconds to determine 0.3-5.0 arcsec positions and perform optical, UV, and X-ray spectrophotometry. Strong education/public outreach and follow-up programs will help to engage the public and astronomical community. The Swift launch is planned for September 2003

Provenance management in Swift with implementation details.

Energy Technology Data Exchange (ETDEWEB)

Gadelha, L. M. R; Clifford, B.; Mattoso, M.; Wilde, M.; Foster, I. (Mathematics and Computer Science); ( CLS-CI); (Federal Univ. of Rio de Janeiro); (National Lab. for Scientific Computing, Brazil); (Univ. of Chicago)

2011-04-01

The Swift parallel scripting language allows for the specification, execution and analysis of large-scale computations in parallel and distributed environments. It incorporates a data model for recording and querying provenance information. In this article we describe these capabilities and evaluate interoperability with other systems through the use of the Open Provenance Model. We describe Swift's provenance data model and compare it to the Open Provenance Model. We also describe and evaluate activities performed within the Third Provenance Challenge, which consisted of implementing a specific scientific workflow, capturing and recording provenance information of its execution, performing provenance queries, and exchanging provenance information with other systems. Finally, we propose improvements to both the Open Provenance Model and Swift's provenance system.

The effects of dissociation on information processing for analogue trauma and neutral stimuli: a laboratory study.

Science.gov (United States)

Olsen, Shira A; Beck, J Gayle

2012-01-01

This study investigated the effects of high and low levels of dissociation on information processing for analogue trauma and neutral stimuli. Fifty-four undergraduate females who reported high and low levels of trait dissociation were presented with two films, one depicting traumatic events, the other containing neutral material. Participants completed a divided attention task (yielding a proxy measure of attention), as well as explicit memory (free-recall) and implicit memory (word-stem completion) tasks for both films. Results indicated that the high DES group showed less attention and had poorer recall for the analogue trauma stimuli, relative to the neutral stimuli and the low DES group. These findings suggest that high levels of trait dissociation are associated with reductions in attention and memory for analogue trauma stimuli, relative to neutral stimuli and relative to low trait dissociation. Implications for the role of cognitive factors in the etiology of negative post-trauma responses are discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

Automatic Analysis of Swift-XRT data

Science.gov (United States)

Evans, P. A.; Tyler, L. G.; Beardmore, A. P.; Osborne, J. P.

2008-08-01

The Swift spacecraft detects and autonomously observes ˜100 Gamma Ray Bursts (GRBs) per year, ˜96% of which are detected by the X-ray telescope (XRT). GRBs are accompanied by optical transients and the field of ground-based follow-up of GRBs has expanded significantly over the last few years, with rapid response instruments capable of responding to Swift triggers on timescales of minutes. To make the most efficient use of limited telescope time, follow-up astronomers need accurate positions of GRBs as soon as possible after the trigger. Additionally, information such as the X-ray light curve, is of interest when considering observing strategy. The Swift team at Leicester University have developed techniques to improve the accuracy of the GRB positions available from the XRT, and to produce science-grade X-ray light curves of GRBs. These techniques are fully automated, and are executed as soon as data are available.

Gliding Swifts Attain Laminar Flow over Rough Wings

NARCIS (Netherlands)

Lentink, D.; Kat, de R.

2014-01-01

Swifts are among the most aerodynamically refined gliding birds. However, the overlapping vanes and protruding shafts of their primary feathers make swift wings remarkably rough for their size. Wing roughness height is 1–2% of chord length on the upper surface—10,000 times rougher than sailplane

The impact of pre-existing anxiety on affective and cognitive processing of a Virtual Reality analogue trauma.

Science.gov (United States)

Schweizer, Tina; Schmitz, Julian; Plempe, Laura; Sun, Dali; Becker-Asano, Christian; Leonhart, Rainer; Tuschen-Caffier, Brunna

2017-01-01

Dysfunctional processing of traumatic events may be in particular related to high trait anxiety as a pre-traumatic risk factor for the development of post-traumatic stress disorder (PTSD). However, as this has rarely been investigated in prospective, experimental studies, we aimed to analyse the association between high trait anxiety and affective as well as cognitive processing of stress using a new prospective Virtual Reality analogue trauma paradigm to overcome limitations of retrospective or current analogue designs. Individuals with high and low trait anxiety (N = 80) were exposed to a multi-sensory Virtual Reality emergency scenario while psychophysiological stress response, emotion regulation and intrusive memories were assessed. Our results showed that high trait anxiety individuals display increased (i) subjective stress responses, (ii) emotion dysregulation and (iii) intrusive memories upon VR analogue trauma exposure. In particular, our sample of high trait anxiety individuals displayed limited access to different emotion regulation strategies as well as increased worry and rumination regarding perceived intrusive memories. Considering the complex interplay of multiple risk factors, our findings suggests that peri-traumatic affective processing seems to mediate high trait anxiety and post-traumatic intrusive memories thereby pointing out the central role of peri-traumatic processes for intrusion development. In addition, HA as a modulating pre-traumatic risk factor might further increase the risk of later dysfunctional processing of an analogue trauma by interacting with factors of affective processing during analogue trauma exposure. Implications of these findings which may contribute to a higher risk to develop PTSD are discussed.

The impact of pre-existing anxiety on affective and cognitive processing of a Virtual Reality analogue trauma.

Directory of Open Access Journals (Sweden)

Tina Schweizer

Full Text Available Dysfunctional processing of traumatic events may be in particular related to high trait anxiety as a pre-traumatic risk factor for the development of post-traumatic stress disorder (PTSD. However, as this has rarely been investigated in prospective, experimental studies, we aimed to analyse the association between high trait anxiety and affective as well as cognitive processing of stress using a new prospective Virtual Reality analogue trauma paradigm to overcome limitations of retrospective or current analogue designs. Individuals with high and low trait anxiety (N = 80 were exposed to a multi-sensory Virtual Reality emergency scenario while psychophysiological stress response, emotion regulation and intrusive memories were assessed. Our results showed that high trait anxiety individuals display increased (i subjective stress responses, (ii emotion dysregulation and (iii intrusive memories upon VR analogue trauma exposure. In particular, our sample of high trait anxiety individuals displayed limited access to different emotion regulation strategies as well as increased worry and rumination regarding perceived intrusive memories. Considering the complex interplay of multiple risk factors, our findings suggests that peri-traumatic affective processing seems to mediate high trait anxiety and post-traumatic intrusive memories thereby pointing out the central role of peri-traumatic processes for intrusion development. In addition, HA as a modulating pre-traumatic risk factor might further increase the risk of later dysfunctional processing of an analogue trauma by interacting with factors of affective processing during analogue trauma exposure. Implications of these findings which may contribute to a higher risk to develop PTSD are discussed.

SWIFT: INTERA simulator for waste injection, flow and transport

International Nuclear Information System (INIS)

Hossain, S.; Arens, G.; Fein, E.

1990-06-01

The latest SWIFT model (SWIFT-GSF2) as available in GSF Braunschweig is described. The theoretical background has been elaborated using the SWIFT II documentation and other available internal notes of various enhancements. Thus the boundary condition implementations and source/sink considerations are now comprehensive. The computer implementation has also been extented to include the description of the matrix solution algorithms. Finally, the data input guide has been updated and when necessary illustrated with figures. The presentation begins with the basic transport equations. (orig.)

Swift Multi-wavelength Observing Campaigns: Strategies and Outcomes

Science.gov (United States)

Krimm, Hans A.

2007-01-01

The Swift gamma-ray burst explorer has been operating since December 2004 as both a gamma-ray burst (GRB) monitor and telescope and a multi-wavelength observatory, covering the energy range from V band and near UV to hard X rays above 150 keV. It is designed to rapidly repoint to observe newly discovered GRBs, and this maneuverability, combined with an easily changed observing program, allows Swift to also be an effective multiwavelength observatory for non-GRB targets, both as targets of opportunity and pre-planned multi-wavelength observing campaigns. Blazars are particularly attractive targets for coordinated campaigns with TeV experiments since many blazars are bright in both the hard X-ray and TeV energy ranges. Successful coordinated campaigns have included observations of 3C454.3 during its 2005 outburst. The latest Swift funding cycles allow for non- GRB related observations to be proposed. The Burst Alert Telescope on Swift also serves as a hard X-ray monitor with a public web page that includes light curves for over 400 X-ray sources and is used to alert the astronomical community about increased activity from both known and newly discovered sources. This presentation mill include Swift capabilities, strategies and policies for coordinated multi-wavelength observations as well as discussion of the potential outcomes of such campaigns.

Highlights of X-Stack ExM Deliverable Swift/T

Energy Technology Data Exchange (ETDEWEB)

Wozniak, Justin M. [Argonne National Lab. (ANL), Argonne, IL (United States)

2016-03-31

Swift/T is a key success from the ExM: System support for extreme-scale, many-task applications1 X-Stack project, which proposed to use concurrent dataflow as an innovative programming model to exploit extreme parallelism in exascale computers. The Swift/T component of the project reimplemented the Swift language from scratch to allow applications that compose scientific modules together to be build and run on available petascale computers (Blue Gene, Cray). Swift/T does this via a new compiler and runtime that generates and executes the application as an MPI program. We assume that mission-critical emerging exascale applications will be composed as scalable applications using existing software components, connected by data dependencies. Developers wrap native code fragments using a higherlevel language, then build composite applications to form a computational experiment. This exemplifies hierarchical concurrency: lower-level messaging libraries are used for fine-grained parallelism; highlevel control is used for inter-task coordination. These patterns are best expressed with dataflow, but static DAGs (i.e., other workflow languages) limit the applications that can be built; they do not provide the expressiveness of Swift, such as conditional execution, iteration, and recursive functions.

Correlative Analysis of GRBs detected by Swift and Suzaku-WAM

International Nuclear Information System (INIS)

Krimm, Hans; Yamaoka, Kazutaka; Sugita, Satoshi; Ohno, Masanori; Tashiro, Makoto; Onda, Kaori; Sato, Goro; Sakamoto, Takanori

2008-01-01

Since most gamma-ray bursts (GRBs) have a peak energy (Epeak) above the energy range (15-150 keV) of the Burst Alert Telescope (BAT) on Swift, a full understanding of the prompt emission from Swift GRBs requires spectral fits over as broad an energy range as possible. This can be done for bursts which are simultaneously detected by Swift BAT and the Suzaku Wide-band All-Sky Monitor (WAM), which covers the energy range from 50-5000 keV. Since the launch of Suzaku in July 2005, there have been 33 gamma-ray bursts (GRBs) which have triggered both Swift and WAM. A joint BAT-WAM team has cross-calibrated the two instruments using GRBs, and we are now able to perform joint fits on these bursts to determine spectral parameters including Epeak. The results of broad spectral fits allows us to understand the distribution of Epeak for Swift bursts and to calibrate Epeak estimators when Epeak is within the BAT energy range. For those bursts with spectroscopic redshifts, we can calculate the isotropic energy and study various correlations between Epeak and other global burst parameters. Here we present preliminary results of joint Swift/BAT-Suzaku/WAM spectral fits

Game development with Swift

CERN Document Server

Haney, Stephen

2015-01-01

If you wish to create and publish fun iOS games using Swift, then this book is for you. You should be familiar with basic programming concepts. However, no prior game development or Apple ecosystem experience is required.

SWIFT-Review: a text-mining workbench for systematic review.

Science.gov (United States)

Howard, Brian E; Phillips, Jason; Miller, Kyle; Tandon, Arpit; Mav, Deepak; Shah, Mihir R; Holmgren, Stephanie; Pelch, Katherine E; Walker, Vickie; Rooney, Andrew A; Macleod, Malcolm; Shah, Ruchir R; Thayer, Kristina

2016-05-23

There is growing interest in using machine learning approaches to priority rank studies and reduce human burden in screening literature when conducting systematic reviews. In addition, identifying addressable questions during the problem formulation phase of systematic review can be challenging, especially for topics having a large literature base. Here, we assess the performance of the SWIFT-Review priority ranking algorithm for identifying studies relevant to a given research question. We also explore the use of SWIFT-Review during problem formulation to identify, categorize, and visualize research areas that are data rich/data poor within a large literature corpus. Twenty case studies, including 15 public data sets, representing a range of complexity and size, were used to assess the priority ranking performance of SWIFT-Review. For each study, seed sets of manually annotated included and excluded titles and abstracts were used for machine training. The remaining references were then ranked for relevance using an algorithm that considers term frequency and latent Dirichlet allocation (LDA) topic modeling. This ranking was evaluated with respect to (1) the number of studies screened in order to identify 95 % of known relevant studies and (2) the "Work Saved over Sampling" (WSS) performance metric. To assess SWIFT-Review for use in problem formulation, PubMed literature search results for 171 chemicals implicated as EDCs were uploaded into SWIFT-Review (264,588 studies) and categorized based on evidence stream and health outcome. Patterns of search results were surveyed and visualized using a variety of interactive graphics. Compared with the reported performance of other tools using the same datasets, the SWIFT-Review ranking procedure obtained the highest scores on 11 out of 15 of the public datasets. Overall, these results suggest that using machine learning to triage documents for screening has the potential to save, on average, more than 50 % of the screening

SWIFT self-teaching curriculum. Illustrative problems to supplement the user's manual for the Sandia Waste-Isolation Flow and Transport model (SWIFT)

International Nuclear Information System (INIS)

Finley, N.C.; Reeves, M.

1982-03-01

This document contains a series of sample problems and solutions for the Sandia Waste-Isolation Flow and Transport (SWIFT) model developed at Sandia National Laboratories for the Risk Methodology for Geologic Disposal of Radioactive Waste Program (A-1192). With this document and the SWIFT User's Manual, the student may familiarize himself with the code, its capabilities and limitations. When the student has completed this curriculum, he or she should be able to prepare data input for SWIFT and have some insights into interpretation of the model output. This report represents one of a series of self-teaching curricula prepared under a technology transfer contract for the US Nuclear Regulatory Commission, Office of Nuclear Material Safety and Safeguards

The Oxford SWIFT integral field spectrograph

Science.gov (United States)

Thatte, Niranjan; Tecza, Matthias; Clarke, Fraser; Goodsall, Timothy; Lynn, James; Freeman, David; Davies, Roger L.

2006-06-01

We present the design of the Oxford SWIFT integral field spectrograph, a dedicated I and z band instrument (0.65μm micron - 1.0μm micron at R~4000), designed to be used in conjunction with the Palomar laser guide star adaptive optics system (PALAO, and its planned upgrade PALM-3000). It builds on two recent developments (i) the improved ability of second generation adaptive optics systems to correct for atmospheric turbulence at wavelengths less than or equal to 1μm micron, and (ii) the availability of CCD array detectors with high quantum efficiency at very red wavelengths (close to the silicon band edge). Combining these with a state-of-the-art integral field unit design using an all-glass image slicer, SWIFT's design provides very high throughput and low scattered light. SWIFT simultaneously provides spectra of ~4000 spatial elements, arranged in a rectangular field-of-view of 44 × 89 pixels. It has three on-the-fly selectable pixel scales of 0.24", 0.16" and 0.08'. First light is expected in spring 2008.

Swift Trust in Distributed Ad Hoc Teams

Science.gov (United States)

2007-10-04

individus sont perçus. Et les abus de confiance commis pendant la mission ont nui temporairement à la réputation de leurs auteurs , mais ils n’ont...of theory and research argue that trust may emerge in teams even when the development of conventional person-based trust is challenged. 1.3.1 Swift...good deal of theory (and some research) espouses the importance of “swift trust” in environments where conventional trust would otherwise be

Behavioural memory reconsolidation of food and fear memories.

Science.gov (United States)

Flavell, Charlotte R; Barber, David J; Lee, Jonathan L C

2011-10-18

The reactivation of a memory through retrieval can render it subject to disruption or modification through the process of memory reconsolidation. In both humans and rodents, briefly reactivating a fear memory results in effective erasure by subsequent extinction training. Here we show that a similar strategy is equally effective in the disruption of appetitive pavlovian cue-food memories. However, systemic administration of the NMDA receptor partial agonist D-cycloserine, under the same behavioural conditions, did not potentiate appetitive memory extinction, suggesting that reactivation does not enhance subsequent extinction learning. To confirm that reactivation followed by extinction reflects a behavioural analogue of memory reconsolidation, we show that prevention of contextual fear memory reactivation by the L-type voltage-gated calcium channel blocker nimodipine interferes with the amnestic outcome. Therefore, the reconsolidation process can be manipulated behaviourally to disrupt both aversive and appetitive memories. © 2011 Macmillan Publishers Limited. All rights reserved.

Flash flood swift water rescues, Texas, 2005–2014

Directory of Open Access Journals (Sweden)

Vaidehi Shah

2017-01-01

Full Text Available Although rainfall patterns are complex and difficult to predict, climate models suggest precipitation in Texas will occur less frequently and with greater intensity in the future. In combination with rapid population growth and development, extreme rainfall events are likely to lead to flash floods and necessitate swift water rescues. Swift water rescues are used to retrieve person(s from swift water flowing at a rate of 1 knot or greater. Data were obtained from the Texas Fire Marshal’s Office and analyzed to describe spatial and temporal characteristics of rescues. Between 2005 and 2014, 3256 swift water rescues were reported from 136 of 254 (54% counties. Over half (54.6%, n = 1777 occurred in counties known as Flash Flood Alley, which includes Texas’ largest and fastest growing cities. Less than 1.0% (n = 18 were reported from 49 counties designated as completely rural, or with an urban population less than 2500. Increases in swift water rescues were seen between March and September and during major weather events such as tropical storms. Because county-level data was utilized and demographic data was missing in all but 2% (n = 47 of the incidents, our ability to identify populations at risk or target interventions in the future using this data is limited. Despite the frequency of flash flood events and swift water rescues in Texas, knowledge gaps persist that should be addressed through the conduct of interdisciplinary research by epidemiologists and climatologists and by disseminating evidence-based health education and safety programs, particularly in rapidly growing counties that make up Texas’ Flash Flood Alley.

Implementing cloud storage with OpenStack Swift

CERN Document Server

Rajana, Kris; Varma, Sreedhar

2014-01-01

This tutorial-based book has a step-by-step approach for each topic, ensuring it is thoroughly covered and easy to follow. If you are an IT administrator who wants to enter the world of cloud storage using OpenStack Swift, then this book is ideal for you. Whether your job is to build, manage, or use OpenStack Swift, this book is an ideal way to move your career ahead. Only basic Linux and server technology skills are expected, to take advantage of this book.

Swift Observations of 2MASS J070931-353746

Science.gov (United States)

Schartel, Dirk Grupe Norbert; Komossa, S.

2018-05-01

We report of Swift observations of 2MASS J070931-353746 which was discovered as a bright X-ray source during an XMM slew on 2018-April-26. Compared with the flux seen during the ROSAT All Sky Survey (Voges et al. 1999) the source appeared to be brighter by a factor of about 16. We performed a short 1ks Swift observation of 2MASS J070931-353746 on 2018-May-18.

Effect of swift heavy ion irradiation on ethylene–chlorotrifluoroethylene copolymer

International Nuclear Information System (INIS)

Singh, Lakhwant; Devgan, Kusum; Samra, Kawaljeet Singh

2012-01-01

The swift heavy irradiation induced changes taking place in ethylene–chlorotrifluoroethylene (E–CTFE) copolymer films were investigated in correlation with the applied doses. Samples were irradiated in vacuum at room temperature by lithium (50 MeV), carbon (85 MeV), nickel (120 MeV) and silver (120 MeV) ions with the fluence in the range of 1×10 11 –3×10 12 ions cm −2 . Structural and thermal properties of the irradiated as well as pristine E–CTFE films were studied using FTIR, UV–visible, TGA, DSC and XRD techniques. Swift heavy ion irradiation was found to induce changes in E–CTFE depending upon the applied doses. - Highlights: ► Effect of swift heavy ion irradiation on E–CTFE films has been studied. ► Different structural changes in the original structure of E–CTFE are observed after irradiation with different ions. ► Swift heavy ion irradiation has made E–CTFE more prone to thermal degradation.

Swift Ultra Long Endurance (SULE) Unmanned Air Vehicle (UAV), Phase II

Data.gov (United States)

National Aeronautics and Space Administration — Swift proposes to design, fabricate, and fly a Swift Ultra Long Endurance (SULE) 30-day mission HALE UAS with flight tests including: 24-hrs, 48-hrs, and 7-days...

The Swift Turbidity Marker

Science.gov (United States)

Omar, Ahmad Fairuz; MatJafri, Mohd Zubir

2011-01-01

The Swift Turbidity Marker is an optical instrument developed to measure the level of water turbidity. The components and configuration selected for the system are based on common turbidity meter design concepts but use a simplified methodology to produce rapid turbidity measurements. This work is aimed at high school physics students and is the…

The Interpretation Of Metaphor Found In 20 Songs Of Taylor Swift

OpenAIRE

Desriani, Shella

2015-01-01

This paper entitled The interpretation of metaphor found in 20 of taylor swift. this paper discuss the types and meaning of metaphor in the lyrics of the song taylor swift. The purpose of this paper is to analyze types of metaphor in the form of simile, personification and hyperbole contained in the lyrics of the song taylor swift. In this paper the authors wrote the paper used the method of literature, collect some data from some books, and the internet. the lyric which contained metaphors i...

Modeling the Swift BAT Trigger Algorithm with Machine Learning

Science.gov (United States)

Graff, Philip B.; Lien, Amy Y.; Baker, John G.; Sakamoto, Takanori

2015-01-01

To draw inferences about gamma-ray burst (GRB) source populations based on Swift observations, it is essential to understand the detection efficiency of the Swift burst alert telescope (BAT). This study considers the problem of modeling the Swift BAT triggering algorithm for long GRBs, a computationally expensive procedure, and models it using machine learning algorithms. A large sample of simulated GRBs from Lien et al. (2014) is used to train various models: random forests, boosted decision trees (with AdaBoost), support vector machines, and artificial neural networks. The best models have accuracies of approximately greater than 97% (approximately less than 3% error), which is a significant improvement on a cut in GRB flux which has an accuracy of 89:6% (10:4% error). These models are then used to measure the detection efficiency of Swift as a function of redshift z, which is used to perform Bayesian parameter estimation on the GRB rate distribution. We find a local GRB rate density of eta(sub 0) approximately 0.48(+0.41/-0.23) Gpc(exp -3) yr(exp -1) with power-law indices of eta(sub 1) approximately 1.7(+0.6/-0.5) and eta(sub 2) approximately -5.9(+5.7/-0.1) for GRBs above and below a break point of z(sub 1) approximately 6.8(+2.8/-3.2). This methodology is able to improve upon earlier studies by more accurately modeling Swift detection and using this for fully Bayesian model fitting. The code used in this is analysis is publicly available online.

Monitoring and Detecting X-ray Transients with the Swift Observatory

Science.gov (United States)

Markwardt, Craig

2002-01-01

Swift is a multi-wavelength observatory specifically designed to detect transients sources in the gamma-ray energy band 15-200 keV. The primary goals of the mission involve gamma ray burst (GRB) astronomy, namely to determine the origin of GRBs and their afterglows, and use bursts to probe the early Universe. However, Swift will also discover new X-ray transient sources, and it will be possible to bring Swift's considerable multi-wavelength capabilities to bear on these sources, and those discovered by other means. The Burst Alert Telescope (BAT) is a coded mask instrument sensitive to 15-200 keV gamma rays, and has a field of view which covers approximately 1/8th of the sky in a single pointing. Over a typical observing day, the almost the entire sky will be observed and monitored for new transient sources. Sources will be detected within several hours of observation. The two narrow field instruments, the X-ray Telescope and Ultra-Violet Optical Telescope, can provide sensitive simultaneous imaging and spectroscopy observations in the optical through soft X-ray bands. The Swift science operations team will entertain requests for targets of opportunity for sources which are astrophysically significant. Swift will be ideally suited for the detection of transients which produce hard X-rays, such as black hole binaries and some neutron star systems.

The leading-edge vortex of swift-wing shaped delta wings

Science.gov (United States)

Muir, Rowan; Arredondo-Galeana, Abel; Viola, Ignazio Maria

2017-11-01

Recent investigations on the aerodynamics of natural fliers have illuminated the significance of the Leading-Edge Vortex (LEV) for lift generation in a variety of flight conditions. In this investigation, a model non-slender delta shaped wing with a sharp leading-edge is tested at low Reynolds Number, along with a delta wing of the same design, but with a modified trailing edge inspired by the wing of a common swift Apus apus. The effect of the tapering swift wing on LEV development and stability is compared with the flow structure over the un-modified delta wing model through particle image velocimetry. For the first time, a leading-edge vortex system consisting of a dual or triple LEV is recorded on a swift-wing shaped delta wing, where such a system is found across all tested conditions. It is shown that the spanwise location of LEV breakdown is governed by the local chord rather than Reynolds Number or angle of attack. These findings suggest that the trailing-edge geometry of the swift wing alone does not prevent the common swift from generating an LEV system comparable with that of a delta shaped wing. This work received funding from the Engineering and Physical Sciences Research Council [EP/M506515/1] and the Consejo Nacional de Ciencia y Tecnología (CONACYT).

Modeling the Swift Bat Trigger Algorithm with Machine Learning

Science.gov (United States)

Graff, Philip B.; Lien, Amy Y.; Baker, John G.; Sakamoto, Takanori

2016-01-01

To draw inferences about gamma-ray burst (GRB) source populations based on Swift observations, it is essential to understand the detection efficiency of the Swift burst alert telescope (BAT). This study considers the problem of modeling the Swift / BAT triggering algorithm for long GRBs, a computationally expensive procedure, and models it using machine learning algorithms. A large sample of simulated GRBs from Lien et al. is used to train various models: random forests, boosted decision trees (with AdaBoost), support vector machines, and artificial neural networks. The best models have accuracies of greater than or equal to 97 percent (less than or equal to 3 percent error), which is a significant improvement on a cut in GRB flux, which has an accuracy of 89.6 percent (10.4 percent error). These models are then used to measure the detection efficiency of Swift as a function of redshift z, which is used to perform Bayesian parameter estimation on the GRB rate distribution. We find a local GRB rate density of n (sub 0) approaching 0.48 (sup plus 0.41) (sub minus 0.23) per cubic gigaparsecs per year with power-law indices of n (sub 1) approaching 1.7 (sup plus 0.6) (sub minus 0.5) and n (sub 2) approaching minus 5.9 (sup plus 5.7) (sub minus 0.1) for GRBs above and below a break point of z (redshift) (sub 1) approaching 6.8 (sup plus 2.8) (sub minus 3.2). This methodology is able to improve upon earlier studies by more accurately modeling Swift detection and using this for fully Bayesian model fitting.

Swift-XRT detects X-ray burst from Circinus X-1

NARCIS (Netherlands)

Linares, M.; Soleri, P.; Altamirano, D.; Armas-Padilla, M.; Cavecchi, Y.; Degenaar, N.; Kalamkar, M.; Kaur, R.; van der Klis, M.; Patruno, A.; Watts, A.; Wijnands, R.; Yang, Y.; Casella, P.; Rea, N.; Chakrabarty, D.; Homan, J.

Following the recent re-brightening (ATel #2608) and RXTE-PCA detection of X-ray bursts from the peculiar X-ray binary Cir X-1 between May 15 and 25 (ATel #2643), we obtained a series of Swift-XRT observations of the field (see also ATel #2650). Swift-XRT detected an X-ray burst on 2010-05-28 at

Analogue Gravity

Directory of Open Access Journals (Sweden)

Carlos Barceló

2011-05-01

Full Text Available Analogue gravity is a research programme which investigates analogues of general relativistic gravitational fields within other physical systems, typically but not exclusively condensed matter systems, with the aim of gaining new insights into their corresponding problems. Analogue models of (and for gravity have a long and distinguished history dating back to the earliest years of general relativity. In this review article we will discuss the history, aims, results, and future prospects for the various analogue models. We start the discussion by presenting a particularly simple example of an analogue model, before exploring the rich history and complex tapestry of models discussed in the literature. The last decade in particular has seen a remarkable and sustained development of analogue gravity ideas, leading to some hundreds of published articles, a workshop, two books, and this review article. Future prospects for the analogue gravity programme also look promising, both on the experimental front (where technology is rapidly advancing and on the theoretical front (where variants of analogue models can be used as a springboard for radical attacks on the problem of quantum gravity.

THE 70 MONTH SWIFT-BAT ALL-SKY HARD X-RAY SURVEY

Energy Technology Data Exchange (ETDEWEB)

Baumgartner, W. H.; Tueller, J.; Markwardt, C. B.; Skinner, G. K.; Barthelmy, S.; Gehrels, N. [NASA/Goddard Space Flight Center, Astrophysics Science Division, Greenbelt, MD 20771 (United States); Mushotzky, R. F. [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); Evans, P. A., E-mail: whbaumga@alum.mit.edu [X-Ray and Observational Astronomy Group/Department of Physics and Astronomy, University of Leicester, Leicester, LE1 7RH (United Kingdom)

2013-08-15

We present the catalog of sources detected in 70 months of observations with the Burst Alert Telescope (BAT) hard X-ray detector on the Swift gamma-ray burst observatory. The Swift-BAT 70 month survey has detected 1171 hard X-ray sources (more than twice as many sources as the previous 22 month survey) in the 14-195 keV band down to a significance level of 4.8{sigma}, associated with 1210 counterparts. The 70 month Swift-BAT survey is the most sensitive and uniform hard X-ray all-sky survey and reaches a flux level of 1.03 Multiplication-Sign 10{sup -11} erg s{sup -1} cm{sup -2} over 50% of the sky and 1.34 Multiplication-Sign 10{sup -11} erg s{sup -1} cm{sup -2} over 90% of the sky. The majority of new sources in the 70 month survey continue to be active galactic nuclei, with over 700 in the catalog. As part of this new edition of the Swift-BAT catalog, we also make available eight-channel spectra and monthly sampled light curves for each object detected in the survey in the online journal and at the Swift-BAT 70 month Web site.

The 105-Month Swift-BAT All-Sky Hard X-Ray Survey

Science.gov (United States)

Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, S. Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail;

THE 70 MONTH SWIFT-BAT ALL-SKY HARD X-RAY SURVEY

International Nuclear Information System (INIS)

Baumgartner, W. H.; Tueller, J.; Markwardt, C. B.; Skinner, G. K.; Barthelmy, S.; Gehrels, N.; Mushotzky, R. F.; Evans, P. A.

2013-01-01

We present the catalog of sources detected in 70 months of observations with the Burst Alert Telescope (BAT) hard X-ray detector on the Swift gamma-ray burst observatory. The Swift-BAT 70 month survey has detected 1171 hard X-ray sources (more than twice as many sources as the previous 22 month survey) in the 14-195 keV band down to a significance level of 4.8σ, associated with 1210 counterparts. The 70 month Swift-BAT survey is the most sensitive and uniform hard X-ray all-sky survey and reaches a flux level of 1.03 × 10 –11 erg s –1 cm –2 over 50% of the sky and 1.34 × 10 –11 erg s –1 cm –2 over 90% of the sky. The majority of new sources in the 70 month survey continue to be active galactic nuclei, with over 700 in the catalog. As part of this new edition of the Swift-BAT catalog, we also make available eight-channel spectra and monthly sampled light curves for each object detected in the survey in the online journal and at the Swift-BAT 70 month Web site

Rapid ex vivo imaging of PAIII prostate to bone tumor with SWIFT-MRI.

Science.gov (United States)

Luhach, Ihor; Idiyatullin, Djaudat; Lynch, Conor C; Corum, Curt; Martinez, Gary V; Garwood, Michael; Gillies, Robert J

2014-09-01

The limiting factor for MRI of skeletal/mineralized tissue is fast transverse relaxation. A recent advancement in MRI technology, SWIFT (Sweep Imaging with Fourier Transform), is emerging as a new approach to overcome this difficulty. Among other techniques like UTE, ZTE, and WASPI, the application of SWIFT technology has the strong potential to impact preclinical and clinical imaging, particularly in the context of primary or metastatic bone cancers because it has the added advantage of imaging water in mineralized tissues of bone allowing MRI images to be obtained of tissues previously visible only with modalities such as computed tomography (CT). The goal of the current study is to examine the feasibility of SWIFT for the assessment of the prostate cancer induced changes in bone formation (osteogenesis) and destruction (osteolysis) in ex vivo specimens. A luciferase expressing prostate cancer cell line (PAIII) or saline control was inoculated directly into the tibia of 6-week-old immunocompromised male mice. Tumor growth was assessed weekly for 3 weeks before euthanasia and dissection of the tumor bearing and sham tibias. The ex vivo mouse tibia specimens were imaged with a 9.4 Tesla (T) and 7T MRI systems. SWIFT images are compared with traditional gradient-echo and spin-echo MRI images as well as CT and histological sections. SWIFT images with nominal resolution of 78 μm are obtained with the tumor and different bone structures identified. Prostate cancer induced changes in the bone microstructure are visible in SWIFT images, which is supported by spin-echo, high resolution CT and histological analysis. SWIFT MRI is capable of high-quality high-resolution ex vivo imaging of bone tumor and surrounding bone and soft tissues. Furthermore, SWIFT MRI shows promise for in vivo bone tumor imaging, with the added benefits of nonexposure to ionizing radiation, quietness, and speed. Copyright © 2013 Wiley Periodicals, Inc.

DARK BURSTS IN THE SWIFT ERA: THE PALOMAR 60 INCH-SWIFT EARLY OPTICAL AFTERGLOW CATALOG

International Nuclear Information System (INIS)

Cenko, S. B.; Harrison, F. A.; Kelemen, J.; Fox, D. B.; Kulkarni, S. R.; Kasliwal, M. M.; Ofek, E. O.; Rau, A.; Gal-Yam, A.; Frail, D. A.; Moon, D.-S.

2009-01-01

We present multicolor optical observations of long-duration γ-ray bursts (GRBs) made over a three-year period with the robotic Palomar 60 inch telescope (P60). Our sample consists of all 29 events discovered by Swift for which P60 began observations less than 1 hr after the burst trigger. We were able to recover 80% of the optical afterglows from this prompt sample, and we attribute this high efficiency to our red coverage. Like Melandri et al. (2008), we find that a significant fraction (∼50%) of Swift events show a suppression of the optical flux with regard to the X-ray emission (the so-called 'dark' bursts). Our multicolor photometry demonstrates this is likely due in large part to extinction in the host galaxy. We argue that previous studies, by selecting only the brightest and best-sampled optical afterglows, have significantly underestimated the amount of dust present in typical GRB environments.

SWIFT BAT Survey of AGN

Science.gov (United States)

Tueller, J.; Mushotzky, R. F.; Barthelmy, S.; Cannizzo, J. K.; Gehrels, N.; Markwardt, C. B.; Skinner, G. K.; Winter, L. M.

2008-01-01

We present the results1 of the analysis of the first 9 months of data of the Swift BAT survey of AGN in the 14-195 keV band. Using archival X-ray data or follow-up Swift XRT observations, we have identified 129 (103 AGN) of 130 objects detected at [b] > 15deg and with significance > 4.8-delta. One source remains unidentified. These same X-ray data have allowed measurement of the X-ray properties of the objects. We fit a power law to the logN - log S distribution, and find the slope to be 1.42+/-0.14. Characterizing the differential luminosity function data as a broken power law, we find a break luminosity logL*(ergs/s)= 43.85+/-0.26. We obtain a mean photon index 1.98 in the 14-195 keV band, with an rms spread of 0.27. Integration of our luminosity function gives a local volume density of AGN above 10(exp 41) erg/s of 2.4x10(exp -3) Mpc(sup -3), which is about 10% of the total luminous local galaxy density above M* = -19.75. We have obtained X-ray spectra from the literature and from Swift XRT follow-up observations. These show that the distribution of log nH is essentially flat from nH = 10(exp 20)/sq cm to 10(exp 24)/sq cm, with 50% of the objects having column densities of less than 10(exp 22)/sq cm. BAT Seyfert galaxies have a median redshift of 0.03, a maximum log luminosity of 45.1, and approximately half have log nH > 22.

Full vehicle ABS braking using the SWIFT rigid ring tyre model

NARCIS (Netherlands)

Pauwelussen, J.P.; Gootjes, L.; Schröder, C.; Köhne, K.-U.; Jansen, S.T.H.; Schmeitz, A.J.C.

2003-01-01

In recent years, at the Delft University of Technology and TNO-Automotive and in conjunction with an industrial consortium, a pragmatic tyre model has been developed going by the name SWIFT, which is geared to the analysis of tyre oscillations and its effects on vehicle behaviour. The SWIFT tyre

An empirical study on the usage of the swift programming language

NARCIS (Netherlands)

Reboucas, M.; Pinto, G.; Ebert, F.; Torres, W.; Serebrenik, A.; Castor, F.

2016-01-01

Recently, Apple released Swift, a modern programming language built to be the successor of Objective-C. In less than a year and a half after its first release, Swift became one of the most popular programming languages in the world, considering different popularity measures. A significant part of

Beyond FMEA: the structured what-if technique (SWIFT).

Science.gov (United States)

Card, Alan J; Ward, James R; Clarkson, P John

2012-01-01

Although it is probably the best-known prospective hazard analysis (PHA) tool, failure mode and effects analysis (FMEA) is far from the only option available. This article introduces one of the alternatives: The structured what-if technique (SWIFT). SWIFT is a flexible, high-level risk identification technique that can be used on a stand-alone basis, or as part of a staged approach to make more efficient use of bottom-up methods like FMEA. In this article we describe the method, assess the evidence related to its use in healthcare with the use of a systematic literature review, and suggest ways in which it could be better adapted for use in the healthcare industry. Based on the limited evidence available, it appears that healthcare workers find it easy to learn, easy to use, and credible. Especially when used as part of a staged approach, SWIFT appears capable of playing a useful role as component of the PHA armamentarium. © 2012 American Society for Healthcare Risk Management of the American Hospital Association.

The leading-edge vortex of swift wing-shaped delta wings.

Science.gov (United States)

Muir, Rowan Eveline; Arredondo-Galeana, Abel; Viola, Ignazio Maria

2017-08-01

Recent investigations on the aerodynamics of natural fliers have illuminated the significance of the leading-edge vortex (LEV) for lift generation in a variety of flight conditions. A well-documented example of an LEV is that generated by aircraft with highly swept, delta-shaped wings. While the wing aerodynamics of a manoeuvring aircraft, a bird gliding and a bird in flapping flight vary significantly, it is believed that this existing knowledge can serve to add understanding to the complex aerodynamics of natural fliers. In this investigation, a model non-slender delta-shaped wing with a sharp leading edge is tested at low Reynolds number, along with a delta wing of the same design, but with a modified trailing edge inspired by the wing of a common swift Apus apus . The effect of the tapering swift wing on LEV development and stability is compared with the flow structure over the unmodified delta wing model through particle image velocimetry. For the first time, a leading-edge vortex system consisting of a dual or triple LEV is recorded on a swift wing-shaped delta wing, where such a system is found across all tested conditions. It is shown that the spanwise location of LEV breakdown is governed by the local chord rather than Reynolds number or angle of attack. These findings suggest that the trailing-edge geometry of the swift wing alone does not prevent the common swift from generating an LEV system comparable with that of a delta-shaped wing.

Gamma-ray burst theory after Swift.

Science.gov (United States)

Piran, Tsvi; Fan, Yi-Zhong

2007-05-15

Afterglow observations in the pre-Swift era confirmed to a large extend the relativistic blast wave model for gamma-ray bursts (GRBs). Together with the observations of properties of host galaxies and the association with (type Ic) SNe, this has led to the generally accepted collapsar origin of long GRBs. However, most of the afterglow data was collected hours after the burst. The X-ray telescope and the UV/optical telescope onboard Swift are able to slew to the direction of a burst in real time and record the early broadband afterglow light curves. These observations, and in particular the X-ray observations, resulted in many surprises. While we have anticipated a smooth transition from the prompt emission to the afterglow, many observed that early light curves are drastically different. We review here how these observations are changing our understanding of GRBs.

Leading-Edge Vortex lifts swifts

NARCIS (Netherlands)

Videler, JJ; Stamhuis, EJ; Povel, GDE

2004-01-01

The current understanding of how birds fly must be revised, because birds use their hand-wings in an unconventional way to generate lift and drag. Physical models of a common swift wing in gliding posture with a 60degrees sweep of the sharp hand-wing leading edge were tested in a water tunnel.

Analogue Gravity

Directory of Open Access Journals (Sweden)

Barceló Carlos

2005-12-01

Full Text Available Analogue models of (and for gravity have a long and distinguished history dating back to the earliest years of general relativity. In this review article we will discuss the history, aims, results, and future prospects for the various analogue models. We start the discussion by presenting a particularly simple example of an analogue model, before exploring the rich history and complex tapestry of models discussed in the literature. The last decade in particular has seen a remarkable and sustained development of analogue gravity ideas, leading to some hundreds of published articles, a workshop, two books, and this review article. Future prospects for the analogue gravity programme also look promising, both on the experimental front (where technology is rapidly advancing and on the theoretical front (where variants of analogue models can be used as a springboard for radical attacks on the problem of quantum gravity.

The 105-Month Swift-BAT All-sky Hard X-Ray Survey

Science.gov (United States)

Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, S. Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail; Ricci, Claudio; Lien, Amy; Trakhtenbrot, Benny

2018-03-01

We present a catalog of hard X-ray sources detected in the first 105 months of observations with the Burst Alert Telescope (BAT) coded-mask imager on board the Swift observatory. The 105-month Swift-BAT survey is a uniform hard X-ray all-sky survey with a sensitivity of 8.40× {10}-12 {erg} {{{s}}}-1 {cm}}-2 over 90% of the sky and 7.24× {10}-12 {erg} {{{s}}}-1 {cm}}-2 over 50% of the sky in the 14–195 keV band. The Swift-BAT 105-month catalog provides 1632 (422 new detections) hard X-ray sources in the 14–195 keV band above the 4.8σ significance level. Adding to the previously known hard X-ray sources, 34% (144/422) of the new detections are identified as Seyfert active galactic nuclei (AGNs) in nearby galaxies (zBAT catalog, we release eight-channel spectra and monthly sampled light curves for each object in the online journal and at the Swift-BAT 105-month website.

Swift captures the spectrally evolving prompt emission of GRB070616

Science.gov (United States)

Starling, R. L. C.; O'Brien, P. T.; Willingale, R.; Page, K. L.; Osborne, J. P.; de Pasquale, M.; Nakagawa, Y. E.; Kuin, N. P. M.; Onda, K.; Norris, J. P.; Ukwatta, T. N.; Kodaka, N.; Burrows, D. N.; Kennea, J. A.; Page, M. J.; Perri, M.; Markwardt, C. B.

2008-02-01

The origins of gamma-ray burst (GRB) prompt emission are currently not well understood and in this context long, well-observed events are particularly important to study. We present the case of GRB070616, analysing the exceptionally long-duration multipeaked prompt emission, and later afterglow, captured by all the instruments on-board Swift and by Suzaku Wide-Band All-Sky Monitor (WAM). The high-energy light curve remained generally flat for several hundred seconds before going into a steep decline. Spectral evolution from hard to soft is clearly taking place throughout the prompt emission, beginning at 285s after the trigger and extending to 1200s. We track the movement of the spectral peak energy, whilst observing a softening of the low-energy spectral slope. The steep decline in flux may be caused by a combination of this strong spectral evolution and the curvature effect. We investigate origins for the spectral evolution, ruling out a superposition of two power laws and considering instead an additional component dominant during the late prompt emission. We also discuss origins for the early optical emission and the physics of the afterglow. The case of GRB070616 clearly demonstrates that both broad-band coverage and good time resolution are crucial to pin down the origins of the complex prompt emission in GRBs. This paper is dedicated to the memory of Dr Francesca Tamburelli who died during its production. Francesca played a fundamental role within the team which is in charge of the development of the Swift X-Ray Telescope (XRT) data analysis software at the Italian Space Agency's Science Data Centre in Frascati. She is sadly missed. E-mail: rlcs1@star.le.ac.uk

Diets of swift foxes (Vulpes velox) in continuous and fragmented prairie in Northwestern Texas

Science.gov (United States)

Kamler, J.F.; Ballard, W.B.; Wallace, M.C.; Gipson, P.S.

2007-01-01

Distribution of the swift fox (Vulpes velox) has declined dramatically since the 1800s, and suggested causes of this decline are habitat fragmentation and transformation due to agricultural expansion. However, impacts of fragmentation and human-altered habitats on swift foxes still are not well understood. To better understand what effects these factors have on diets of swift foxes, scats were collected in northwestern Texas at two study sites, one of continuous native prairie and one representing fragmented native prairie interspersed with agricultural and fields in the Conservation Reserve Program. Leporids, a potential food source, were surveyed seasonally on both sites. Diets of swift foxes differed between sites; insects were consumed more on continuous prairie, whereas mammals, birds, and crops were consumed more on fragmented prairie. Size of populations of leporids were 2-3 times higher on fragmented prairie, and swift foxes responded by consuming more leporids on fragmented (11.1% frequency occurrence) than continuous (3.8%) prairie. Dietary diversity was greater on fragmented prairie during both years of the study. Differences in diets between sites suggested that the swift fox is an adaptable and opportunistic feeder, able to exploit a variety of food resources, probably in relation to availability of food. We suggest that compared to continuous native prairie, fragmented prairie can offer swift foxes a more diverse prey base, at least within the mosaic of native prairie, agricultural, and fields that are in the Conservation Reserve Program.

SWIFTS: on-chip very high spectral resolution spectrometer

Science.gov (United States)

le Coarer, E.; Venancio, L. G.; Kern, P.; Ferrand, J.; Puget, P.; Ayraud, M.; Bonneville, C.; Demonte, B.; Morand, A.; Boussey, J.; Barbier, D.; Blaize, S.; Gonthiez, T.

2017-11-01

The size and the weight of state of the art spectrometers is a serious issue regarding space applications. SWIFTS (Stationary Wave Integrated Fourier Transform Spectrometer) is a new FTS family without any moving part. This very promising technology is an original way to fully sample the Fourier interferogram obtained in a waveguide by either a reflection (SWIFTS Lippmann) or counter-propagative (SWIFTS Gabor) interference phenomenon. The sampling is simultaneously performed the optical path thanks to "nano-detectors" located in the evanescent field of the waveguide. For instance a 1.7cm long waveguide properly associated to the detector achieves directly a resolution of 0.13cm-1 on a few centimetre long instruments. Here, firstly we present the development status of this new kind of spectrometers and the first results obtained with on going development of spectrometer covering simultaneously the visible domain from 400 to 1000 nm like an Echelle spectrometer. Valuable technologies allows one to extend the concept to various wavelength domains. Secondly, we present the results obtained in the frame of an activity funded by the European Space Agency where several potential applications in space missions have been identified and studied.

Swift Data Products in GCN

Science.gov (United States)

Barthelmy, Scott D.

2006-09-01

The Swift mission produces a much larger range of data products for the GRB Coordinates Distribution (GCN) system than any previous mission. Beyond the normal position-containing notices, the extra products are lightcurves, spectra, and images. We will present examples of these new data products and how they can be used to guide GRB follow-up observation campaigns.

DETAILED CLASSIFICATION OF SWIFT 'S GAMMA-RAY BURSTS

International Nuclear Information System (INIS)

Horvath, I.; Veres, P.; Bagoly, Z.; Balazs, L. G.; De Ugarte Postigo, A.; Meszaros, A.

2010-01-01

Earlier classification analyses found three types of gamma-ray bursts (short, long, and intermediate in duration) in the BATSE sample. Recent works have shown that these three groups are also present in the RHESSI and BeppoSAX databases. The duration distribution analysis of the bursts observed by the Swift satellite also favors the three-component model. In this paper, we extend the analysis of the Swift data with spectral information. We show, using the spectral hardness and duration simultaneously, that the maximum likelihood method favors the three-component against the two-component model. The likelihood also shows that a fourth component is not needed.

OpenStack Object Storage (Swift) essentials

CERN Document Server

Kapadia, Amar; Varma, Sreedhar

2015-01-01

If you are an IT administrator and you want to enter the world of cloud storage using OpenStack Swift, then this book is ideal for you. Basic knowledge of Linux and server technology is beneficial to get the most out of the book.

Power Performance Test Report for the SWIFT Wind Turbine

Energy Technology Data Exchange (ETDEWEB)

Mendoza, I.; Hur, J.

2012-12-01

This report summarizes the results of a power performance test that NREL conducted on the SWIFT wind turbine. This test was conducted in accordance with the International Electrotechnical Commission's (IEC) standard, Wind Turbine Generator Systems Part 12: Power Performance Measurements of Electricity Producing Wind Turbines, IEC 61400-12-1 Ed.1.0, 2005-12. However, because the SWIFT is a small turbine as defined by IEC, NREL also followed Annex H that applies to small wind turbines. In these summary results, wind speed is normalized to sea-level air density.

THE SWIFT AGN AND CLUSTER SURVEY. II. CLUSTER CONFIRMATION WITH SDSS DATA

International Nuclear Information System (INIS)

Griffin, Rhiannon D.; Dai, Xinyu; Kochanek, Christopher S.; Bregman, Joel N.

2016-01-01

We study 203 (of 442) Swift AGN and Cluster Survey extended X-ray sources located in the SDSS DR8 footprint to search for galaxy over-densities in three-dimensional space using SDSS galaxy photometric redshifts and positions near the Swift cluster candidates. We find 104 Swift clusters with a >3σ galaxy over-density. The remaining targets are potentially located at higher redshifts and require deeper optical follow-up observations for confirmation as galaxy clusters. We present a series of cluster properties including the redshift, brightest cluster galaxy (BCG) magnitude, BCG-to-X-ray center offset, optical richness, and X-ray luminosity. We also detect red sequences in ∼85% of the 104 confirmed clusters. The X-ray luminosity and optical richness for the SDSS confirmed Swift clusters are correlated and follow previously established relations. The distribution of the separations between the X-ray centroids and the most likely BCG is also consistent with expectation. We compare the observed redshift distribution of the sample with a theoretical model, and find that our sample is complete for z ≲ 0.3 and is still 80% complete up to z ≃ 0.4, consistent with the SDSS survey depth. These analysis results suggest that our Swift cluster selection algorithm has yielded a statistically well-defined cluster sample for further study of cluster evolution and cosmology. We also match our SDSS confirmed Swift clusters to existing cluster catalogs, and find 42, 23, and 1 matches in optical, X-ray, and Sunyaev–Zel’dovich catalogs, respectively, and so the majority of these clusters are new detections

Detection of Highly-Absorbed X-rays from Nova Mus 2018 with Swift

Science.gov (United States)

Nelson, Thomas; Kuin, Paul; Mukai, Koji; Page, Kim; Chomiuk, Laura; Kawash, Adam; Sokoloski, J. L.; Linford, Justin; Rupen, Michael P.; Mioduszewski, Amy

2018-03-01

We report the detection of X-rays from Nova Mus 2018 with the Swift XRT instrument. We have been carrying out weekly monitoring of the nova with Swift since its discovery on 2018 Jan 15 (see ATel #11220), and observations up to 2018 Feb 24 yielded X-ray non-detections.

Fermi-LAT Gamma-Ray Bursts and Insights from Swift

Science.gov (United States)

Racusin, Judith L.

2010-01-01

A new revolution in Gamma-ray Burst (GRB) observations and theory has begun over the last two years since the launch of the Fermi Gamma-ray Space Telescope. The new window into high energy gamma-rays opened by the Fermi-Large Area Telescope (LAT) is providing insight into prompt emission mechanisms and possibly also afterglow physics. The LAT detected GRBs appear to be a new unique subset of extremely energetic and bright bursts compared to the large sample detected by Swift over the last 6 years. In this talk, I will discuss the context and recent discoveries from these LAT GRBs and the large database of broadband observations collected by the Swift X-ray Telescope (XRT) and UV/Optical Telescope (UVOT). Through comparisons between the GRBs detected by Swift-BAT, G8M, and LAT, we can learn about the unique characteristics, physical differences, and the relationships between each population. These population characteristics provide insight into the different physical parameters that contribute to the diversity of observational GRB properties.

The Simpsons: Public Choice in the Tradition of Swift and Orwell

Science.gov (United States)

Considine, John

2006-01-01

The author disagrees with Homer Simpson who claims that "...cartoons don't have any deep meaning. They're just stupid drawings that give you a cheap laugh." He argues that The Simpsons have a deep meaning in the same way as the works of Jonathan Swift and George Orwell. The message in The Simpsons, Swift, and Orwell is that those in charge do not…

Immobilization of swift foxes with ketamine hydrochloride-xylazine hydrochloride

Science.gov (United States)

Telesco, R.L.; Sovada, Marsha A.

2002-01-01

There is an increasing need to develop field immobilization techniques that allow researchers to handle safely swift foxes (Vulpes velox) with minimal risk of stress or injury. We immobilized captive swift foxes to determine the safety and effectiveness of ketamine hydrochloride and xylazine hydrochloride at different dosages. We attempted to determine appropriate dosages to immobilize swift foxes for an adequate field-handling period based on three anesthesia intervals (induction period, immobilization period, and recovery period) and physiologic responses (rectal temperature, respiration rate, and heart rate). Between October 1998–July 1999, we conducted four trials, evaluating three different dosage ratios of ketamine and xylazine (2.27:1.2, 5.68:1.2, and 11.4:1.2 mg/kg ketamine:mg/kg xylazine, respectively), followed by a fourth trial with a higher dosage at the median ratio (11.4 mg/kg ketamine:2.4 mg/kg xylazine). We found little difference in induction and recovery periods among trials 1–3, but immobilization time increased with increasing dosage (Pimmobilization period and recovery period increased in trial 4 compared with trials 1–3 (P≤0.03). There was a high variation in responses of individual foxes across trials, making it difficult to identify an appropriate dosage for field handling. Heart rate and respiration rates were depressed but all physiologic measures remained within normal parameters established for domestic canids. We recommend a dosage ratio of 10 mg/kg ketamine to 1 mg/kg xylazine to immobilize swift foxes for field handling.

Analysis of the Swift Gamma-Ray Bursts duration

International Nuclear Information System (INIS)

Horvath, I.; Veres, P.; Balazs, L. G.; Kelemen, J.; Bagoly, Z.; Tusnady, G.

2008-01-01

Two classes of gamma-ray bursts have been identified in the BATSE catalogs characterized by durations shorter and longer than about 2 seconds. There are, however, some indications for the existence of a third type of burst. Swift satellite detectors have different spectral sensitivity than pre-Swift ones for gamma-ray bursts. Therefore it is worth to reanalyze the durations and their distribution and also the classification of GRBs. Using The First BAT Catalog the maximum likelihood estimation was used to analyzed the duration distribution of GRBs. The three log-normal fit is significantly (99.54% probability) better than the two for the duration distribution. Monte-Carlo simulations also confirm this probability (99.2%).

The X-ray Telescope for the SWIFT Gamma-Ray Burst Mission

International Nuclear Information System (INIS)

Wells, A.; Abbey, A.F.; Beardmore, A.; Mukerjee, K.; Osborne, J.P.; Watson, D.J.; Willingale, R.; Burrows, D. N.; Hill, J. E.; Nousek, J.A.; Miles, B.J.; Mori, K.; Morris, D.C.; Zugger, M.; Chincarini, G.; Campana, S.; Citterio, O.; Moretti, A.; Tagliaferri, G.; Bosworth, J.

2004-01-01

The X-ray Telescope (XRT) for the SWIFT mission, built by the international consortium from Pennsylvania State University (United States), University of Leicester (UK) and Osservatorio Astronomico di Brera (Italy), is already installed on the SWIFT spacecraft. The XRT has two key functions on SWIFT; to determine locations of GRBs to better than 5 arc seconds within 100 seconds of initial detection of a burst and to measure spectra and light curves of the X-ray afterglow over around four orders of magnitude of decay in the afterglow intensity. This paper summarises the XRT performance, operating modes and sensitivity for the detection of prompt and extended X-ray afterglows from gamma-ray bursts. The performance characteristics have been determined from data taken during the ground calibration campaign at MPE's Panter facility in September 2002

The Oxford SWIFT Spectrograph: first commissioning and on-sky results

Science.gov (United States)

Thatte, Niranjan; Tecza, Mathias; Clarke, Fraser; Goodsall, Timothy; Fogarty, Lisa; Houghton, Ryan; Salter, Graeme; Scott, Nicholas; Davies, Roger L.; Bouchez, Antonin; Dekany, Richard

2010-07-01

The Oxford SWIFT spectrograph, an I & z band (6500-10500 A) integral field spectrograph, is designed to operate as a facility instrument at the 200 inch Hale Telescope on Palomar Mountain, in conjunction with the Palomar laser guide star adaptive optics system PALAO (and its upgrade to PALM3000). SWIFT provides spectra at R(≡λ/▵λ)~4000 of a contiguous two-dimensional field, 44 x 89 spatial pixels (spaxels) in size, at spatial scales of 0.235", 0.16", and 0.08" per spaxel. It employs two 250μm thick, fully depleted, extremely red sensitive 4k X 2k CCD detector arrays (manufactured by LBNL) that provide excellent quantum efficiency out to 1000 nm. We describe the commissioning observations and present the measured values of a number of instrument parameters. We also present some first science results that give a taste of the range of science programs where SWIFT can have a substantial impact.

Continued INTEGRAL observations of Swift J1658.2-4242: brighter and softer?

Science.gov (United States)

Grinberg, V.; Eikmann, W.; Kreykenbohm, I.; Wilms, J.

2018-02-01

INTEGRAL continued its observations of the new X-ray transient Swift J1658.2-4242 (GCN #22416 and #22417). The source was originally interpreted as a black hole X-ray binary due to its spectral shape (ATel #11306) but the detection of a pulsation with Swift (ATel #11311) points towards an accreting X-ray pulsar interpretation.

Seven years with the Swift Supergiant Fast X-ray Transients project

Science.gov (United States)

Romano, P.

2015-09-01

Supergiant Fast X-ray Transients (SFXTs) are HMXBs with OB supergiant companions. I review the results of the Swift SFXT project, which since 2007 has been exploiting Swift's capabilities in a systematic study of SFXTs and supergiant X-ray binaries (SGXBs) by combining follow-ups of outbursts, when detailed broad-band spectroscopy is possible, with long-term monitoring campaigns, when the out-of-outburst fainter states can be observed. This strategy has led us to measure their duty cycles as a function of luminosity, to extract their differential luminosity distributions in the soft X-ray domain, and to compare, with unprecedented detail, the X-ray variability in these different classes of sources. I also discuss the ;seventh year crisis;, the challenges that the recent Swift observations are making to the prevailing models attempting to explain the SFXT behavior.

Swift fox survey along Heartland Expressway Corridor.

Science.gov (United States)

2015-05-01

The swift fox (Vulpes velox) is a small canid classified as endangered within the : state of Nebraska. Future construction of the Heartland Expressway Corridor (HEC), a : 300 km road expansion project in the panhandle of the state, may impact the res...

Nonlinear effects in interactions of swift ions with solids

International Nuclear Information System (INIS)

Crawford, O.H.; Dorado, J.J.; Flores, F.

1994-01-01

The passage of a swift charged particle through a solid gives rise to a wake of induced electron density behind the particle. It is calculated for a proton penetrating an electron gas having the density of the valence electrons in gold, assuming linear response of the medium. The induced potential associated with the wake is responsible for the energy loss of the particle, and for many effects that have captured recent interest. These include, among others, vicinage effects on swift ion clusters, emission of electrons from bombarded solids, forces on swift ions near a surface, and energy shifts in electronic states of channeled ions. Furthermore, the wake has a determining influence on the spatial distribution, and character, of energy deposition in the medium. Previous theoretical studies of these phenomena have employed a linear wake, i.e., one that is proportional to the charge of the projectile, eZ. However, in most experiments that measure these effects, the conditions are such that the wake must include higher-order terms in Z. The purpose of this study is to analyze the nonlinear wake, to understand how the linear results must be revised

Finding AGN in Deep X-ray Flux States with Swift

OpenAIRE

Grupe, Dirk; Komossa, S.; Bush, Mason; Pruett, Chelsea; Ernst, Sonny; Barber, Taylor; Carter, Jen; Schartel, Norbert; Rodriguez, Pedro; Santos-Lleó, Maria

2015-01-01

We report on our ongoing project of finding Active Galactic Nuclei (AGN) that go into deep X-ray flux states detected by Swift. Swift is performing an extensive study on the flux and spectral variability of AGN using Guest Investigator and team fill-in programs followed by triggering XMM_Newton for deeper follow-up observations. So far this program has been very successful and has led to a number of XMM-Newton follow up observations, including Mkn 335, PG 0844+349, and RX J2340.8-5329. Recent...

The Oxford SWIFT Spectrograph: first commissioning and on-sky results

OpenAIRE

Thatte, Niranjan; Tecza, Mathias; Clarke, Fraser; Goodsall, Timothy; Fogarty, Lisa; Houghton, Ryan; Salter, Graeme; Scott, Nicholas; Davies, Roger L.; Bouchez, Antonin; Dekany, Richard

2010-01-01

The Oxford SWIFT spectrograph, an I & z band (6500-10500 A) integral field spectrograph, is designed to operate as a facility instrument at the 200 inch Hale Telescope on Palomar Mountain, in conjunction with the Palomar laser guide star adaptive optics system PALAO (and its upgrade to PALM3000). SWIFT provides spectra at R(≡λ/▵λ)~4000 of a contiguous two-dimensional field, 44 x 89 spatial pixels (spaxels) in size, at spatial scales of 0.235";, 0.16", and 0.08" per spaxel. It employs two 250μ...

Analogue MIMO Detection

Directory of Open Access Journals (Sweden)

McNamara Darren

2006-01-01

Full Text Available In this contribution we propose an analogue receiver that can perform turbo detection in MIMO systems. We present the case for a receiver that is built from nonlinear analogue devices, which perform detection in a "free-flow" network (no notion of iterations. This contribution can be viewed as an extension of analogue turbo decoder concepts to include MIMO detection. These first analogue implementations report reductions of few orders of magnitude in the number of required transistors and in consumed energy, and the same order of improvement in processing speed. It is anticipated that such analogue MIMO decoder could bring about the same advantages, when compared to traditional digital implementations.

Gamma Ray Burst Discoveries by the Swift Mission

Science.gov (United States)

Gehrels, Neil

2006-01-01

Gamma-ray bursts are among the most fascinating occurrences in the cosmos. They are thought to be the birth cries of black holes throughout the universe. The NASA swift mission is an innovative new multiwavelength observatory designed to determine the origin of bursts and use them to probe the early Universe. Swift is now in orbit since November 20, 2004 and all hardware is performing well. A new-technology wide-field gamma-ray camera is detecting a hundred bursts per year. sensitive narrow-field X-ray and uv/optical telescopes, built in collaboration with UK and Italian partners, are pointed at the burst location in 50-100 sec by an autonomously controlled "swift" spacecraft. For each burst, arcsec positions are determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. Information is also rapidly sent to the ground to a team of more than 50 observers at telescopes around the world. The first year of findings from the mission will be presented. There has been a break-through in the longstanding mystery of short GRBs; they appear to be caused by merging neutron stars. High redshift bursts have been detected leading to a better understanding of star formation rates and distant galaxy environments. GRBs have been found with giant X-ray flares occurring in their afterglow.

Gamma Ray Burst Discoveries by the Swift Mission

Science.gov (United States)

Gehrels, Neil

2006-04-01

Gamma-ray bursts are among the most fascinating occurrences in the cosmos. They are thought to be the birth cries of black holes throughout the universe. The NASA Swift mission is an innovative new multiwavelength observatory designed to determine the origin of bursts and use them to probe the early Universe. Swift is now in orbit since November 20, 2004 and all hardware is performing well. A new-technology wide-field gamma-ray camera is detecting a hundred bursts per year. Sensitive narrow-field X-ray and UV/optical telescopes, built in collaboration with UK and Italian partners, are pointed at the burst location in 50-100 sec by an autonomously controlled ``swift'' spacecraft. For each burst, arcsec positions are determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. Information is also rapidly sent to the ground to a team of more than 50 observers at telescopes around the world. The first year of findings from the mission will be presented. There has been a break-through in the long-standing mystery of short GRBs; they appear to be caused by merging neutron stars. High redshift bursts have been detected leading to a better understanding of star formation rates and distant galaxy environments. GRBs have been found with giant X-ray flares occurring in their afterglow.

VizieR Online Data Catalog: Swift-UVOT obs. analysis of 29 SNe Ia (Brown+, 2017)

Science.gov (United States)

Brown, P. J.; Landez, N. J.; Milne, P. A.; Stritzinger, M. D.

2017-10-01

Swift/UVOT has observed over 500 SNe of all types in its 12 years of operation (see Brown+ 2015JHEAp...7..111B for a review of the first 10yrs). Most of the observations use six UV and optical filters. All photometry comes from the Swift Optical/Ultraviolet Supernova Archive (SOUSA; Brown+ 2014Ap&SS.354...89B) and is available at the Swift SN website and the Open Supernova Archive (Guillochon+ 2017ApJ...835...64G). (1 data file).

iOS game development : Mobile game development with Swift programming language and SceneKit framework

OpenAIRE

Koskenseppä, Juuso

2016-01-01

The purpose of the thesis was to create an iOS game that could be deemed complete enough, so it could be published in Apple’s App Store. This meant fulfilling different guide-lines specified by Apple. The project was carried out by using Apple’s new Swift programming language and SceneKit framework, with an intention to see how they work for iOS game development. The immaturity of Swift programming language led to several code rewrites, every time a newer Swift version was released. T...

Species distribution model for swift fox in Nebraska.

Science.gov (United States)

2016-11-28

The grasslands of Nebraska are highly altered due to anthropogenic development and : degradation. The loss and degradation of grasslands has significantly impacted populations of : swift fox (Vulpes velox), a Nebraska Natural Legacy Plan Tier1 at ...

The Extrapolar SWIFT model (version 1.0): fast stratospheric ozone chemistry for global climate models

Science.gov (United States)

Kreyling, Daniel; Wohltmann, Ingo; Lehmann, Ralph; Rex, Markus

2018-03-01

The Extrapolar SWIFT model is a fast ozone chemistry scheme for interactive calculation of the extrapolar stratospheric ozone layer in coupled general circulation models (GCMs). In contrast to the widely used prescribed ozone, the SWIFT ozone layer interacts with the model dynamics and can respond to atmospheric variability or climatological trends.The Extrapolar SWIFT model employs a repro-modelling approach, in which algebraic functions are used to approximate the numerical output of a full stratospheric chemistry and transport model (ATLAS). The full model solves a coupled chemical differential equation system with 55 initial and boundary conditions (mixing ratio of various chemical species and atmospheric parameters). Hence the rate of change of ozone over 24 h is a function of 55 variables. Using covariances between these variables, we can find linear combinations in order to reduce the parameter space to the following nine basic variables: latitude, pressure altitude, temperature, overhead ozone column and the mixing ratio of ozone and of the ozone-depleting families (Cly, Bry, NOy and HOy). We will show that these nine variables are sufficient to characterize the rate of change of ozone. An automated procedure fits a polynomial function of fourth degree to the rate of change of ozone obtained from several simulations with the ATLAS model. One polynomial function is determined per month, which yields the rate of change of ozone over 24 h. A key aspect for the robustness of the Extrapolar SWIFT model is to include a wide range of stratospheric variability in the numerical output of the ATLAS model, also covering atmospheric states that will occur in a future climate (e.g. temperature and meridional circulation changes or reduction of stratospheric chlorine loading).For validation purposes, the Extrapolar SWIFT model has been integrated into the ATLAS model, replacing the full stratospheric chemistry scheme. Simulations with SWIFT in ATLAS have proven that the

OPTICAL STUDIES OF 13 HARD X-RAY SELECTED CATACLYSMIC BINARIES FROM THE SWIFT-BAT SURVEY

International Nuclear Information System (INIS)

Halpern, Jules P.; Thorstensen, John R.

2015-01-01

From a set of 13 cataclysmic binaries that were discovered in the Swift Burst Alert Telescope (BAT) survey, we conducted time-resolved optical spectroscopy and/or time-series photometry of 11, with the goal of measuring their orbital periods and searching for spin periods. Seven of the objects in this study are new optical identifications. Orbital periods are found for seven targets, ranging from 81 minutes to 20.4 hr. PBC J0706.7+0327 is an AM Herculis star (polar) based on its emission-line variations and large amplitude photometric modulation on the same period. Swift J2341.0+7645 may be a polar, although the evidence here is less secure. Coherent pulsations are detected from two objects, Swift J0503.7−2819 (975 s) and Swift J0614.0+1709 (1412 s and 1530 s, spin and beat periods, respectively), indicating that they are probable intermediate polars (DQ Herculis stars). For two other stars, longer spin periods are tentatively suggested. We also present the discovery of a 2.00 hr X-ray modulation from RX J2015.6+3711, possibly a contributor to Swift J2015.9+3715, and likely a polar

MF-Swift simulation study using benchmark data

NARCIS (Netherlands)

Jansen, S.T.H.; Verhoeff, L.; Cremers, R.; Schmeitz, A.J.C.; Besselink, I.J.M.

2005-01-01

The accuracy of tyre models depends to a large extent on the measurement data used to assess model parameters. The MF-Swift tyre model parameters can be identified or estimated from various combinations of experimental data. The amount and required accuracy of the measurement data can be selected

Simultaneous Chandra/Swift Observations of the RT Cru Symbiotic System

Science.gov (United States)

Kashyap, Vinay; Kennea, J. A.; Karovska, M.; Calibration, Chandra

2013-04-01

The symbiotic star RT Cru was observed simultaneously by the Chandra/HRC-I and Swift/XRT in Dec 2012. The observations were carried out as part of a program to calibrate the Chandra PSF. The Chandra light curve shows a number of brightenings by factors of 2, with strong indications of a softening of the spectrum at these times. Swift observations cover a brief part of the Chandra light curve, and the intensities over this duration are tightly correlated. The Swift spectral data confirm the anticorrelation between intensity and spectral hardness. However, there are differences in the correlations at different periods that are not understood. We report on our analysis of the data, with emphasis on the spectral modeling at different times and intensity levels, and discuss the implications of the results on the emission mechanisms on symbiotic stars. We also report our inferences on the structure and energy dependence of the Chandra PSF anomaly, and on the high-energy cross-calibration between the HRC-I and XRT. This work is supported by the NASA contract NAS8-03060 to the Chandra X-ray Center.

Folding two dimensional crystals by swift heavy ion irradiation

International Nuclear Information System (INIS)

Ochedowski, Oliver; Bukowska, Hanna; Freire Soler, Victor M.; Brökers, Lara; Ban-d'Etat, Brigitte; Lebius, Henning; Schleberger, Marika

2014-01-01

Ion irradiation of graphene, the showcase model of two dimensional crystals, has been successfully applied to induce various modifications in the graphene crystal. One of these modifications is the formation of origami like foldings in graphene which are created by swift heavy ion irradiation under glancing incidence angle. These foldings can be applied to locally alter the physical properties of graphene like mechanical strength or chemical reactivity. In this work we show that the formation of foldings in two dimensional crystals is not restricted to graphene but can be applied for other materials like MoS 2 and hexagonal BN as well. Further we show that chemical vapour deposited graphene forms foldings after swift heavy ion irradiation while chemical vapour deposited MoS 2 does not

Fermi-LAT Gamma-ray Bursts and Insight from Swift

Science.gov (United States)

Racusin, Judith L.

2011-01-01

A new revolution in GRB observation and theory has begun over the last 3 years since the launch of the Fermi gamma-ray space telescope. The new window into high energy gamma-rays opened by the Fermi-LAT is providing insight into prompt emission mechanisms and possibly also afterglow physics. The LAT detected GRBs appear to be a new unique subset of extremely energetic and bright bursts. In this talk I will discuss the context and recent discoveries from these LAT GRBs and the large database of broadband observations collected by Swift over the last 7 years and how through comparisons between the Swift, GBM, and LAT GRB samples, we can learn about the unique characteristics and relationships between each population.

Testing the E(sub peak)-E(sub iso) Relation for GRBs Detected by Swift and Suzaku-WAM

Science.gov (United States)

Krimm, H. A.; Yamaoka, K.; Sugita, S.; Ohno, M.; Sakamoto, T.; Barthelmy, S. D.; Gehrels, N.; Hara, R.; Onda, K.; Sato, G.;

Precision of working memory for speech sounds.

Science.gov (United States)

Joseph, Sabine; Iverson, Paul; Manohar, Sanjay; Fox, Zoe; Scott, Sophie K; Husain, Masud

2015-01-01

Memory for speech sounds is a key component of models of verbal working memory (WM). But how good is verbal WM? Most investigations assess this using binary report measures to derive a fixed number of items that can be stored. However, recent findings in visual WM have challenged such "quantized" views by employing measures of recall precision with an analogue response scale. WM for speech sounds might rely on both continuous and categorical storage mechanisms. Using a novel speech matching paradigm, we measured WM recall precision for phonemes. Vowel qualities were sampled from a formant space continuum. A probe vowel had to be adjusted to match the vowel quality of a target on a continuous, analogue response scale. Crucially, this provided an index of the variability of a memory representation around its true value and thus allowed us to estimate how memories were distorted from the original sounds. Memory load affected the quality of speech sound recall in two ways. First, there was a gradual decline in recall precision with increasing number of items, consistent with the view that WM representations of speech sounds become noisier with an increase in the number of items held in memory, just as for vision. Based on multidimensional scaling (MDS), the level of noise appeared to be reflected in distortions of the formant space. Second, as memory load increased, there was evidence of greater clustering of participants' responses around particular vowels. A mixture model captured both continuous and categorical responses, demonstrating a shift from continuous to categorical memory with increasing WM load. This suggests that direct acoustic storage can be used for single items, but when more items must be stored, categorical representations must be used.

From Adam Swift to Adam Smith: How the "Invisible Hand" Overcomes Middle Class Hypocrisy

Science.gov (United States)

Tooley, James

2007-01-01

This paper challenges Richard Pring's suggestion that parents using private education may be undermining the desire for social justice and equality, using recent arguments of Adam Swift as a springboard. Swift's position on the banning of private schools, which uses a Rawlsian "veil of ignorance" argument, is explored, and it is suggested that, if…

Swiftly moving focus points and forming shapes through the scattering media

Science.gov (United States)

Tran, Vinh; Sahoo, Sujit Kumar; Tang, Dongliang; Dang, Cuong

2018-02-01

Propagation of light through scattering media such as ground glass or biological tissue limits the quality and intensity of focusing point. Wave front shaping technique which uses spatial light modulator (SLM) devices to reshape the field profile of incoming light, is considered as one of the most effective and convenient methods. Advanced biomedical or manufacturing applications require drawing various contours or shapes quickly and precisely. However, creating each shape behind the scattering medium needs different phase profiles, which are time consuming to optimize or measure. Here, we demonstrate a technique to draw various shapes or contours behind the scattering medium by swiftly moving the focus point without any mechanical movements. Our technique relies on the existence of speckle correlation property in scattering media, also known as optical memory effect. In our procedure, we first modulate the phase-only SLM to create the focus point on the other side of scattering medium. Then, we digitally shift the preoptimized phase profile on the SLM and ramp it to tilt the beam accordingly. Now, the incoming beam with identical phase profile shines on the same scattering region at a tilted angle to regenerate the focus point at the desired position due to memory effect. Moreover, with linear combination of different field patterns, we can generate a single phase profile on SLM to produce two, three or more focus points simultaneously on the other side of a turbid medium. Our method could provide a useful tool for prominent applications such as opto-genetic excitation, minimally invasive laser surgery and other related fields.

Roles of calcium/calmodulin-dependent kinase II in long-term memory formation in crickets.

Directory of Open Access Journals (Sweden)

Makoto Mizunami

Full Text Available Ca(2+/calmodulin (CaM-dependent protein kinase II (CaMKII is a key molecule in many systems of learning and memory in vertebrates, but roles of CaMKII in invertebrates have not been characterized in detail. We have suggested that serial activation of NO/cGMP signaling, cyclic nucleotide-gated channel, Ca(2+/CaM and cAMP signaling participates in long-term memory (LTM formation in olfactory conditioning in crickets, and here we show participation of CaMKII in LTM formation and propose its site of action in the biochemical cascades. Crickets subjected to 3-trial conditioning to associate an odor with reward exhibited memory that lasts for a few days, which is characterized as protein synthesis-dependent LTM. In contrast, animals subjected to 1-trial conditioning exhibited memory that lasts for only several hours (mid-term memory, MTM. Injection of a CaMKII inhibitor prior to 3-trial conditioning impaired 1-day memory retention but not 1-hour memory retention, suggesting that CaMKII participates in LTM formation but not in MTM formation. Animals injected with a cGMP analogue, calcium ionophore or cAMP analogue prior to 1-trial conditioning exhibited 1-day retention, and co-injection of a CaMKII inhibitor impaired induction of LTM by the cGMP analogue or that by the calcium ionophore but not that by the cAMP analogue, suggesting that CaMKII is downstream of cGMP production and Ca(2+ influx and upstream of cAMP production in biochemical cascades for LTM formation. Animals injected with an adenylyl cyclase (AC activator prior to 1-trial conditioning exhibited 1-day retention. Interestingly, a CaMKII inhibitor impaired LTM induction by the AC activator, although AC is expected to be a downstream target of CaMKII. The results suggest that CaMKII interacts with AC to facilitate cAMP production for LTM formation. We propose that CaMKII serves as a key molecule for interplay between Ca(2+ signaling and cAMP signaling for LTM formation, a new role of Ca

Nucleation control and separation of paracetamol polymorphs through swift cooling crystallization process

Science.gov (United States)

Sudha, C.; Srinivasan, K.

2014-09-01

Polymorphic nucleation behavior of pharmaceutical solid paracetamol has been investigated by performing swift cooling crystallization process. Saturated aqueous solution prepared at 318 K was swiftly cooled to 274 K in steps of every 1 K in the temperature range from 274 K to 313 K with uniform stirring of 100 rpm. The resultant supersaturation generated in the mother solution favours the nucleation of three different polymorphs of paracetamol. Lower supersaturation region σ=0.10-0.83 favours stable mono form I; the intermediate supersaturation region σ=0.92-1.28 favours metastable ortho form II and the higher supersaturation region σ=1.33-1.58 favours unstable form III polymorphic nucleation. Depending upon the level of supersaturation generated during swift cooling process and the corresponding solubility limit and metastable zone width (MSZW) of each polymorph, the nucleation of a particular polymorph occurs in the system. The type of polymorphs was identified by in-situ optical microscopy and the internal structure was confirmed by Powder X-ray diffraction (PXRD) study. By this novel approach, the preferred nucleation regions of all the three polymorphs of paracetamol are optimized in terms of different cooling ranges employed during the swift cooling process. Also solution mediated polymorphic transformations from unstable to mono and ortho to mono polymorphs have been studied by in-situ.

Magnetar Observations in the Swift-Fermi/GBM Era

Science.gov (United States)

Kouveliotou, Chryssa

2010-01-01

NASA's Fermi Observatory was launched June 11, 2008; the Fermi Gamma Ray Burst Monitor (GBM) began normal operations on July 14, about a month after launch, when the trigger algorithms were enabled. Since then, and against all odds, GBM recorded over 600 bursts from 4 SGRs. Of these four sources, only one was an old magnetar: SGR J1806+20. SGR J0501+4516, was discovered with Swift and extensively monitored with GBM. A source originally classified as AXP 1E1547.0-5408 exhibited SGR-like bursting behavior and we reclassified it as SGR J1550-5418. Finally, GBM discovered SGR J0418+5729 on 2009 June. Finally, on March 2010, a third new magnetar was discovered with Swift, SGR J1833-0832. I report below on the current status of the field and on several results combining multi-satellite and ground-based data

Den site activity patterns of adult male and female swift foxes, Vulpes velox, in Northwestern Texas

Science.gov (United States)

Lemons, P.R.; Ballard, W.B.; Sullivan, R.M.; Sovada, M.A.

2003-01-01

Activity of Swift Foxes (Vulpes velox) at den sites was studied in northwestern Texas during pup rearing seasons in 2000 and 2001 to determine role of males in parental care. Twenty-four percent of radio-collared females with a potential to breed successfully raised pups to eight weeks of age. We intensively monitored presence and absence of male and female Swift Foxes at two den sites each year. Females were present >2.6 times more at den sites than males during the pup rearing season. Female and male Swift Foxes largely stayed at dens during diurnal hours and were active away from dens during nocturnal and crepuscular hours. Females and males spent 12.4% and 3.0% more time at dens before pups emerged, than after pups emerged, respectively. Following depredation of one male parent, the female spent 29% less time at the den site. Decrease in time spent at the den by the female following loss of her mate suggested that loss of one parent might severely impact recruitment of Swift Foxes. Our observations indicated that intense Coyote (Canis latrans) depredation may severely impact pup-rearing success as well as the parental care within Swift Fox family groups.

Age-specific survival of reintroduced swift fox in Badlands National Park and surrounding lands

Science.gov (United States)

Sasmal, Indrani; Klaver, Robert W.; Jenks, Jonathan A.; Schroeder, Greg M.

2016-01-01

In 2003, a reintroduction program was initiated at Badlands National Park (BNP), South Dakota, USA, with swift foxes (Vulpes velox) translocated from Colorado and Wyoming, USA, as part of a restoration effort to recover declining swift fox populations throughout its historical range. Estimates of age-specific survival are necessary to evaluate the potential for population growth of reintroduced populations. We used 7 years (2003–2009) of capture–recapture data of 243 pups, 29 yearlings, and 69 adult swift foxes at BNP and the surrounding area to construct Cormack–Jolly–Seber model estimates of apparent survival within a capture–mark–recapture framework using Program MARK. The best model for estimating recapture probabilities included no differences among age classes, greater recapture probabilities during early years of the monitoring effort than later years, and variation among spring, winter, and summer. Our top ranked survival model indicated pup survival differed from that of yearlings and adults and varied by month and year. The apparent annual survival probability of pups (0.47, SE = 0.10) in our study area was greater than the apparent annual survival probability of yearlings and adults (0.27, SE = 0.08). Our results indicate low survival probabilities for a reintroduced population of swift foxes in the BNP and surrounding areas. Management of reintroduced populations and future reintroductions of swift foxes should consider the effects of relative low annual survival on population demography.

VizieR Online Data Catalog: Swift Master Catalog (HEASARC, 2004-)

Science.gov (United States)

Nasa; Heasarc

2018-01-01

This table records high-level information for each Swift observation and provides access to the data archive. Each record is associated with a single observation that contains data from all instruments on board Swift. The BAT is the large field of view instrument and operates in the 10-300 keV energy band. The narrow field instruments, XRT and UVOT, operate in the X-ray and UV/optical regime, respectively. An observation is defined as a collection of snapshots, where a snapshot is defined as the time spent observing the same position continuously. Because of observing constraints, the length of a snapshot can be shorter than a single orbit and it can be interrupted because the satellite will point in a different direction of the sky or because the time allocated to that observation ends. The typical Swift observing strategy for a Gamma Ray Burst (GRB) and/or afterglow, consists of a serious of observations aimed at following the GRB and its afterglow evolution. This strategy is achieved with two different type of observations named Automatic Targets and Pre-Planned Targets. The Automatic Target is initiated on board soon after an event is triggered by the BAT. The Figure of Merit (FOM) algorithm, part of the observatory's autonomy, decides if it is worth requesting a slew maneuver to point the narrow field instruments (NFI) on Swift, XRT and UVOT, in the direction of the trigger. If the conditions to slew to the new position are satisfied, the Automatic Target observation takes place; all the instruments have a pre-set standard configuration of operating modes and filters and about 20000 seconds on source will be collected. The Pre-Planned Target observations instead are initiated from the ground once the trigger is known. These observations are planned on ground and uploaded onto the spacecraft. (1 data file).

The HEASARC Swift Gamma-Ray Burst Archive: The Pipeline and the Catalog

Science.gov (United States)

Donato, Davide; Angelini, Lorella; Padgett, C.A.; Reichard, T.; Gehrels, Neil; Marshall, Francis E.; Sakamoto, Takanori

2012-01-01

Since its launch in late 2004, the Swift satellite triggered or observed an average of one gamma-ray burst (GRB) every 3 days, for a total of 771 GRBs by 2012 January. Here, we report the development of a pipeline that semi automatically performs the data-reduction and data-analysis processes for the three instruments on board Swift (BAT, XRT, UVOT). The pipeline is written in Perl, and it uses only HEAsoft tools and can be used to perform the analysis of a majority of the point-like objects (e.g., GRBs, active galactic nuclei, pulsars) observed by Swift. We run the pipeline on the GRBs, and we present a database containing the screened data, the output products, and the results of our ongoing analysis. Furthermore, we created a catalog summarizing some GRB information, collected either by running the pipeline or from the literature. The Perl script, the database, and the catalog are available for downloading and querying at the HEASARC Web site.

A Social Wellbeing in Fisheries Tool (SWIFT to Help Improve Fisheries Performance

Directory of Open Access Journals (Sweden)

Tracy Van Holt

2016-07-01

Full Text Available We report on a rapid and practical method to assess social dimensions of performance in small-scale and industrial fisheries globally (Social Wellbeing in Fisheries Tool (SWIFT. SWIFT incorporates aspects of security (fairness and stability of earnings, benefits of employment to local fishing communities, worker protection, and personal safety and health in communities associated with fisheries; flexibility (including opportunity for economic advancement; and the fishery’s social viability (including whether the fishery is recruiting new harvesters and diverse age classes of workers, whether women’s participation and leadership in global production networks are on an upward trajectory.. We build on resilience research by conceptualizing wellbeing in terms of security, flexibility, and viability, and assessing wellbeing at individual, community, and system levels. SWIFT makes social performance measures more broadly accessible to global production networks, incorporates an everyday understanding of wellbeing for people involved in the seafood industry, and helps put social sustainability into measurable terms that are relevant for businesses.

Folding two dimensional crystals by swift heavy ion irradiation

Energy Technology Data Exchange (ETDEWEB)

Ochedowski, Oliver; Bukowska, Hanna [Fakultät für Physik and CENIDE, Universität Duisburg-Essen, D-47048 Duisburg (Germany); Freire Soler, Victor M. [Fakultät für Physik and CENIDE, Universität Duisburg-Essen, D-47048 Duisburg (Germany); Departament de Fisica Aplicada i Optica, Universitat de Barcelona, E08028 Barcelona (Spain); Brökers, Lara [Fakultät für Physik and CENIDE, Universität Duisburg-Essen, D-47048 Duisburg (Germany); Ban-d' Etat, Brigitte; Lebius, Henning [CIMAP (CEA-CNRS-ENSICAEN-UCBN), 14070 Caen Cedex 5 (France); Schleberger, Marika, E-mail: marika.schleberger@uni-due.de [Fakultät für Physik and CENIDE, Universität Duisburg-Essen, D-47048 Duisburg (Germany)

2014-12-01

Ion irradiation of graphene, the showcase model of two dimensional crystals, has been successfully applied to induce various modifications in the graphene crystal. One of these modifications is the formation of origami like foldings in graphene which are created by swift heavy ion irradiation under glancing incidence angle. These foldings can be applied to locally alter the physical properties of graphene like mechanical strength or chemical reactivity. In this work we show that the formation of foldings in two dimensional crystals is not restricted to graphene but can be applied for other materials like MoS{sub 2} and hexagonal BN as well. Further we show that chemical vapour deposited graphene forms foldings after swift heavy ion irradiation while chemical vapour deposited MoS{sub 2} does not.

Swift follow-up of the newly discovered burster millisecond pulsar IGR J17511-3057

DEFF Research Database (Denmark)

Bozzo, E.; Ferrigno, C.; Kuulkers, E.

2009-01-01

Following the discovery of the new hard X-ray transient IGR J17511-3057 by INTEGRAL (Atel #2196) and its classification as a millisecond pulsar by RXTE (Atel #2197), a Swift ToO was performed. Swift/XRT observed IGR J17511-3057 on 2009-09-13 at 19:53:31 for a total exposure time of 4 ks. The first...

SWIFT: Semi-empirical and numerically efficient stratospheric ozone chemistry for global climate models

OpenAIRE

Kreyling, Daniel; Wohltmann, Ingo; Lehmann, Ralph; Rex, Markus

2015-01-01

The SWIFT model is a fast yet accurate chemistry scheme for calculating the chemistry of stratospheric ozone. It is mainly intended for use in Global Climate Models (GCMs), Chemistry Climate Models (CCMs) and Earth System Models (ESMs). For computing time reasons these models often do not employ full stratospheric chem- istry modules, but use prescribed ozone instead. This can lead to insufficient representation between stratosphere and troposphere. The SWIFT stratospheric ozone chem...

Probing the Cosmic Gamma-Ray Burst Rate with Trigger Simulations of the Swift Burst Alert Telescope

Science.gov (United States)

Lien, Amy; Sakamoto, Takanori; Gehrels, Neil; Palmer, David M.; Barthelmy, Scott D.; Graziani, Carlo; Cannizzo, John K.

2013-01-01

The gamma-ray burst (GRB) rate is essential for revealing the connection between GRBs, supernovae and stellar evolution. Additionally, the GRB rate at high redshift provides a strong probe of star formation history in the early universe. While hundreds of GRBs are observed by Swift, it remains difficult to determine the intrinsic GRB rate due to the complex trigger algorithm of Swift. Current studies of the GRB rate usually approximate the Swift trigger algorithm by a single detection threshold. However, unlike the previously own GRB instruments, Swift has over 500 trigger criteria based on photon count rate and additional image threshold for localization. To investigate possible systematic biases and explore the intrinsic GRB properties, we develop a program that is capable of simulating all the rate trigger criteria and mimicking the image threshold. Our simulations show that adopting the complex trigger algorithm of Swift increases the detection rate of dim bursts. As a result, our simulations suggest bursts need to be dimmer than previously expected to avoid over-producing the number of detections and to match with Swift observations. Moreover, our results indicate that these dim bursts are more likely to be high redshift events than low-luminosity GRBs. This would imply an even higher cosmic GRB rate at large redshifts than previous expectations based on star-formation rate measurements, unless other factors, such as the luminosity evolution, are taken into account. The GRB rate from our best result gives a total number of 4568 +825 -1429 GRBs per year that are beamed toward us in the whole universe.

The 2014 X-Ray Minimum of η Carinae as Seen by Swift

Energy Technology Data Exchange (ETDEWEB)

Corcoran, M. F.; Hamaguchi, K. [CRESST and X-Ray Astrophysics Laboratory, NASA/Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Liburd, J.; Morris, D. [University of the Virgin Islands, College of Science and Mathematics, John Brewers Bay, St. Thomas, USVI 00802-9990 (United States); Russell, C. M. P. [NASA Goddard Space Flight Center, Code 662, Greenbelt, MD 20771 (United States); Gull, T. R. [NASA Goddard Space Flight Center, Code 667, Greenbelt, MD 20771 (United States); Madura, T. I. [Department of Physics and Astronomy, San Jose State University, One Washington Square, San Jose, CA 95192 (United States); Teodoro, M. [Universities Space Research Association, 7178 Columbia Gateway Drive, Columbia, MD 21044 (United States); Moffat, A. F. J. [Département de physique and Centre de Recherche en Astrophysique du Québec (CRAQ), Université de Montréal, C.P. 6128, Succ. Centre-Ville, Montréal, Québec, H3C 3J7 (Canada); Richardson, N. D. [Ritter Observatory, Department of Physics and Astronomy, The University of Toledo, Toledo, OH 43606 (United States); Hillier, D. J. [Department of Physics and Astronomy and Pittsburgh Particle Physics, Astrophysics, and Cosmology Center (PITT PACC), University of Pittsburgh, 3941 O’Hara Street, Pittsburgh, PA 15260 (United States); Damineli, A. [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, Rua do Matão 1226, Cidade Universitária, São Paulo, 05508-900 (Brazil); Groh, J. H. [School of Physics, Trinity College Dublin, Dublin 2 (Ireland)

2017-03-20

We report on Swift X-ray Telescope observations of Eta Carinae ( η Car), an extremely massive, long-period, highly eccentric binary obtained during the 2014.6 X-ray minimum/periastron passage. These observations show that η Car may have been particularly bright in X-rays going into the X-ray minimum state, while the duration of the 2014 X-ray minimum was intermediate between the extended minima seen in 1998.0 and 2003.5 by Rossi X-Ray Timing Explorer ( RXTE ), and the shorter minimum in 2009.0. The hardness ratios derived from the Swift observations showed a relatively smooth increase to a peak value occurring 40.5 days after the start of the X-ray minimum, though these observations cannot reliably measure the X-ray hardness during the deepest part of the X-ray minimum when contamination by the “central constant emission” component is significant. By comparing the timings of the RXTE and Swift observations near the X-ray minima, we derive an updated X-ray period of P {sub X} = 2023.7 ± 0.7 days, in good agreement with periods derived from observations at other wavelengths, and we compare the X-ray changes with variations in the He ii 4686 emission. The middle of the “Deep Minimum” interval, as defined by the Swift column density variations, is in good agreement with the time of periastron passage derived from the He ii λ 4686 line variations.

A note on a representation and calculation of the long-memory Ornstein-Uhlenbeck process

DEFF Research Database (Denmark)

Høg, Esben

1999-01-01

In this paper we analyze the covariance function for a long memory generalization of Ornstein-Uhlenbeck type processes which are the analogues in continuous time of long memory autoregressions of order 1. A Fractional Brownian Motion with drift is a special case. We find the exact expression...

X-RAY OBSERVATIONS OF THE NEW UNUSUAL MAGNETAR SWIFT J1834.9–0846

International Nuclear Information System (INIS)

Kargaltsev, Oleg; Kouveliotou, Chryssa; Younes, George; Pavlov, George G.; Göğüş, Ersin; Lin, Lin; Kaneko, Yuki; Wachter, Stefanie; Griffith, Roger L.

2012-01-01

We present X-ray observations of the new transient magnetar Swift J1834.9–0846, discovered with the Swift Burst Alert Telescope on 2011 August 7. The data were obtained with Swift, Rossi X-ray Timing Explorer (RXTE), CXO, and XMM-Newton both before and after the outburst. Timing analysis reveals single peak pulsations with a period of 2.4823 s and an unusually high pulsed fraction, 85% ± 10%. Using the RXTE and CXO data, we estimated the period derivative, P-dot =8×10 -12 s s –1 , and confirmed the high magnetic field of the source, B = 1.4 × 10 14 G. The decay of the persistent X-ray flux, spanning 48 days, is consistent with a power law, F∝t –0.5 . In the CXO/Advanced CCD Imaging Spectrometer image, we find that the highly absorbed point source is surrounded by extended emission, which most likely is a dust scattering halo. Swift J1834.9–0846 is located near the center of the radio supernova remnant W41 and TeV source HESS J1834–087. An association with W41 would imply a source distance of about 4 kpc; however, any relation to the HESS source remains unclear, given the presence of several other candidate counterparts for the latter source in the field. Our search for an IR counterpart of Swift J1834.9–0846 revealed no source down to K s ∼ 19.5 within the 0.''6 CXO error circle.

Impact-parameter-dependent electronic stopping of swift ions

NARCIS (Netherlands)

Schinner, A.; Sigmund, P.

2010-01-01

A computational scheme has been developed to estimate the mean electronic energy loss of an incident swift ion on an atomic target as a function of the impact parameter between the moving nuclei. The theoretical basis is binary stopping theory. In order to extract impact-parameter dependencies it

Seattle wide-area information for travelers (SWIFT) : architecture study

Science.gov (United States)

1998-10-19

The SWIFT (Seattle Wide-area Information For Travelers) Field Operational Test was intended to evaluate the performance of a large-scale urban Advanced Traveler Information System (ATIS) deployment in the Seattle area. The unique features of the SWIF...

Swift X-ray monitoring of stellar coronal variability

Science.gov (United States)

Miller, Brendan; Hagen, Cedric; Gallo, Elena; Wright, Jason T.

2018-01-01

We used California Planet Search Ca II H and K core emission measurements to identify and characterize chromospheric activity cycles in a sample of main-sequence FGK stars. About a dozen of these with existing ROSAT archival data were targeted with Swift to obtain a current epoch X-ray flux. We find that coronal variability by a factor of several is common on decade-long timescales (we attempt to link to the chromospheric cycle phase) but can also occur on short timescales between Swift visits to a given target, presumably related to stellar rotation and coronal inhomogeneity or to small flares. Additionally, we present new Swift monitoring observations of two M dwarfs with known exoplanets: GJ 15A and GJ 674. GJ 15A b is around 5.3 Earth masses with an 11.4 day orbital period, while GJ 674 is around 11.1 Earth masses with a 4.7 day orbital period. GJ 15A was observed several times in late 2014 and then monitored at approximately weekly intervals for several months in early 2016, for a total exposure of 18 ks. GJ 674 was monitored at approximately weekly intervals for most of 2016, for a total exposure of 40 ks. We provide light curves and hardness ratios for both sources, and also compare to earlier archival X-ray data. Both sources show significant X-ray variability, including between consecutive observations. We quantify the energy distribution for coronal flaring, and compare to optical results for M dwarfs from Kepler. Finally, we discuss the implications of M dwarf coronal activity for exoplanets orbiting within the nominal habitable zone.

Surface amorphization in Al2O3 induced by swift heavy ion irradiation

International Nuclear Information System (INIS)

Okubo, N.; Ishikawa, N.; Sataka, M.; Jitsukawa, S.

2013-01-01

Microstructure in single crystalline Al 2 O 3 developed during irradiation by swift heavy ions has been investigated. The specimens were irradiated by Xe ions with energies from 70 to 160 MeV at ambient temperature. The fluences were in the range from 1.0 × 10 13 to 1.0 × 10 15 ions/cm 2 . After irradiations, X-ray diffractometry (XRD) measurements and cross sectional transmission electron microscope (TEM) observations were conducted. The XRD results indicate that in the initial stage of amorphization in single crystalline Al 2 O 3 , high-density S e causes the formation of new planes and disordering. The new distorted lattice planes formed in the early stage of irradiation around the fluence of 5.0 × 10 13 ions/cm 2 for single crystalline Al 2 O 3 irradiated with 160 MeV-Xe ions. Energy dependence on structural modification was also examined in single crystalline Al 2 O 3 irradiated by swift heavy ions. The XRD results indicate that the swift heavy ion irradiation causes the lattice expansion and the structural modification leading to amorphization progresses above the energy around 100 MeV in this XRD study. The TEM observations demonstrated that amorphization was induced in surface region in single crystalline Al 2 O 3 irradiated by swift heavy ions above the fluence expected from the results of XRD. Obvious boundary was observed in the cross sectional TEM images. The crystal structure of surface region above the boundary was identified to be amorphous and deeper region to be single crystal. The threshold fluence of amorphization was found to be around 1.0 × 10 14 ions/cm 2 in the case over 80 MeV swift heavy ion irradiation and the fluence did not depend on the crystal structures

Surface amorphization in Al2O3 induced by swift heavy ion irradiation

Science.gov (United States)

Okubo, N.; Ishikawa, N.; Sataka, M.; Jitsukawa, S.

2013-11-01

Microstructure in single crystalline Al2O3 developed during irradiation by swift heavy ions has been investigated. The specimens were irradiated by Xe ions with energies from 70 to 160 MeV at ambient temperature. The fluences were in the range from 1.0 × 1013 to 1.0 × 1015 ions/cm2. After irradiations, X-ray diffractometry (XRD) measurements and cross sectional transmission electron microscope (TEM) observations were conducted. The XRD results indicate that in the initial stage of amorphization in single crystalline Al2O3, high-density Se causes the formation of new planes and disordering. The new distorted lattice planes formed in the early stage of irradiation around the fluence of 5.0 × 1013 ions/cm2 for single crystalline Al2O3 irradiated with 160 MeV-Xe ions. Energy dependence on structural modification was also examined in single crystalline Al2O3 irradiated by swift heavy ions. The XRD results indicate that the swift heavy ion irradiation causes the lattice expansion and the structural modification leading to amorphization progresses above the energy around 100 MeV in this XRD study. The TEM observations demonstrated that amorphization was induced in surface region in single crystalline Al2O3 irradiated by swift heavy ions above the fluence expected from the results of XRD. Obvious boundary was observed in the cross sectional TEM images. The crystal structure of surface region above the boundary was identified to be amorphous and deeper region to be single crystal. The threshold fluence of amorphization was found to be around 1.0 × 1014 ions/cm2 in the case over 80 MeV swift heavy ion irradiation and the fluence did not depend on the crystal structures.

The Successful Synergy of Swift and Fermi/GBM in Magnetars

Science.gov (United States)

Kouveliotou, Chryssa

2011-01-01

The magnetar rate of discovery has increased dramatically in the last decade. Five sources were discovered in the last three years alone as a result of the very efficient synergy among three X- and .gamma-ray instruments on NASA satellites: the Swift/Burst Alert Telescope (BAT), the Fermi/Gamma ray Burst Monitor (GBM), and the Rossi X-Ray Timing Explorer; RXTE/Proportional Counter Array (PCA). To date, there are approx. 25 magnetar candidates, of which two are (one each) in the Large and Small Magellanic Cloud and the rest reside on the Galactic plane of our Milky Way. I will discuss here the main properties of the Magnetar Population and the common projects that can be achieved with the synergy of Swift and GBM.

Sex differences in a human analogue of the Radial Arm Maze: the "17-Box Maze Test".

Science.gov (United States)

Rahman, Qazi; Abrahams, Sharon; Jussab, Fardin

2005-08-01

This study investigated sex differences in spatial memory using a human analogue of the Radial Arm Maze: a revision on the Nine Box Maze originally developed by called the 17-Box Maze Test herein. The task encourages allocentric spatial processing, dissociates object from spatial memory, and incorporates a within-participants design to provide measures of location and object, working and reference memory. Healthy adult males and females (26 per group) were administered the 17-Box Maze Test, as well as mental rotation and a verbal IQ test. Females made significantly fewer errors on this task than males. However, post hoc analysis revealed that the significant sex difference was specific to object, rather than location, memory measures. These were medium to large effect sizes. The findings raise the issue of task- and component-specific sexual dimorphism in cognitive mapping.

The Prompt-afterglow Connection in Gamma-ray Bursts: a Comprehensive Statistical Analysis of Swift X-ray Light-curves

Science.gov (United States)

Margutti, R.; Zaninoni, E.; Bernardini, M. G.; Chincarini, G.; Pasotti, F.; Guidorzi, C.; Angelini, Lorella; Burrows, D. N.; Capalbi, M.; Evans, P. A.;

Low emotional response to traumatic footage is associated with an absence of analogue flashbacks: an individual participant data meta-analysis of 16 trauma film paradigm experiments.

Science.gov (United States)

Clark, Ian A; Mackay, Clare E; Holmes, Emily A

2015-01-01

Most people will experience or witness a traumatic event. A common occurrence after trauma is the experience of involuntary emotional memories of the traumatic event, herewith "flashbacks". Some individuals, however, report no flashbacks. Prospective work investigating psychological factors associated with an absence of flashbacks is lacking. We performed an individual participant data meta-analysis on 16 experiments (n = 458) using the trauma film paradigm to investigate the association of emotional response to traumatic film footage and commonly collected baseline characteristics (trait anxiety, current depression, trauma history) with an absence of analogue flashbacks. An absence of analogue flashbacks was associated with low emotional response to the traumatic film footage and, to a lesser extent, low trait anxiety and low current depression levels. Trauma history and recognition memory for the film were not significantly associated with an absence of analogue flashbacks. Understanding why some individuals report an absence of flashbacks may aid preventative treatments against flashback development.

Afterglow Population Studies from Swift Follow-Up Observations of Fermi LAT GRBs

Science.gov (United States)

Racusin, Judith L.; Oates, S. R.; McEnery, J.; Vasileiou, V.; Troja, E.; Gehrels, N.

2010-01-01

The small population of Fermi LAT detected GRBs discovered over the last year has been providing interesting and unexpected clues into GRB prompt and afterglow emission mechanisms. Over the last 5 years, it has been Swift that has provided the robust data set of UV/optical and X-ray afterglow observations that opened many windows into other components of GRB emission structure. We explore the new ability to utilize both of these observatories to study the same GRBs over 10 orders of magnitude in energy, although not always concurrently. Almost all LAT GRBs that have been followed-up by Swift within 1-day have been clearly detected and carefully observed. We will present the context of the lower-energy afterglows of this special subset of GRBs that has > 100 MeV emission compared to the hundreds in the Swift database that may or may not have been observed by LAT, and theorize upon the relationship between these properties and the origin of the high energy gamma-ray emission.

A ROTATIONALLY POWERED MAGNETAR NEBULA AROUND SWIFT J1834.9–0846

Energy Technology Data Exchange (ETDEWEB)

Torres, Diego F. [Institute of Space Sciences (IEEC-CSIC), Campus UAB, Carrer de Magrans s/n, E-08193 Barcelona (Spain)

2017-01-20

A wind nebula generating extended X-ray emission was recently detected surrounding Swift J1834.9–0846. This is the first magnetar for which such a wind nebula was found. Here, we investigate whether there is a plausible scenario where the pulsar wind nebula (PWN) can be sustained without the need of advocating for additional sources of energy other than rotational. We do this by using a detailed radiative and dynamical code that studies the evolution of the nebula and its particle population in time. We find that such a scenario indeed exists: Swift J1834.9–0846's nebula can be explained as being rotationally powered, as all other known PWNe are, if it is currently being compressed by the environment. The latter introduces several effects, the most important of which is the appearance of adiabatic heating, being increasingly dominant over the escape of particles as reverberation goes by. The need of reverberation naturally explains why this is the only magnetar nebula detected and provides estimates for Swift 1834.9–0846's age.

Rethinking of the criteria for natural analogue study. A case of Tono natural analogue study

International Nuclear Information System (INIS)

Yoshida, Hidekazu

1996-01-01

Natural analogue regarding long-term performance of the geological disposal system for radioactive waste isolation is essentially the study of geochemical process which has been evolved in geological environment. All geochemical studies, however, will not be nominated as natural analogue studies. It is, therefore, important to be clear the criteria for natural analogue study with the view of analogy by following three categories, (1) Conceptual model development, (2) Data provision and (3) Model testing, for the concept of geological disposal and safety assessment model. Rethinking of the criteria for natural analogue study through the case of Tono Natural Analogue Study, and the usefulness of natural analogue study for the safety assessment of geological disposal system in Japan have been presented in this paper. (author)

Efficiency of Lift Production in Flapping and Gliding Flight of Swifts

Science.gov (United States)

Henningsson, Per; Hedenström, Anders; Bomphrey, Richard J.

2014-01-01

Many flying animals use both flapping and gliding flight as part of their routine behaviour. These two kinematic patterns impose conflicting requirements on wing design for aerodynamic efficiency and, in the absence of extreme morphing, wings cannot be optimised for both flight modes. In gliding flight, the wing experiences uniform incident flow and the optimal shape is a high aspect ratio wing with an elliptical planform. In flapping flight, on the other hand, the wing tip travels faster than the root, creating a spanwise velocity gradient. To compensate, the optimal wing shape should taper towards the tip (reducing the local chord) and/or twist from root to tip (reducing local angle of attack). We hypothesised that, if a bird is limited in its ability to morph its wings and adapt its wing shape to suit both flight modes, then a preference towards flapping flight optimization will be expected since this is the most energetically demanding flight mode. We tested this by studying a well-known flap-gliding species, the common swift, by measuring the wakes generated by two birds, one in gliding and one in flapping flight in a wind tunnel. We calculated span efficiency, the efficiency of lift production, and found that the flapping swift had consistently higher span efficiency than the gliding swift. This supports our hypothesis and suggests that even though swifts have been shown previously to increase their lift-to-drag ratio substantially when gliding, the wing morphology is tuned to be more aerodynamically efficient in generating lift during flapping. Since body drag can be assumed to be similar for both flapping and gliding, it follows that the higher total drag in flapping flight compared with gliding flight is primarily a consequence of an increase in wing profile drag due to the flapping motion, exceeding the reduction in induced drag. PMID:24587260

Efficiency of lift production in flapping and gliding flight of swifts.

Directory of Open Access Journals (Sweden)

Per Henningsson

Full Text Available Many flying animals use both flapping and gliding flight as part of their routine behaviour. These two kinematic patterns impose conflicting requirements on wing design for aerodynamic efficiency and, in the absence of extreme morphing, wings cannot be optimised for both flight modes. In gliding flight, the wing experiences uniform incident flow and the optimal shape is a high aspect ratio wing with an elliptical planform. In flapping flight, on the other hand, the wing tip travels faster than the root, creating a spanwise velocity gradient. To compensate, the optimal wing shape should taper towards the tip (reducing the local chord and/or twist from root to tip (reducing local angle of attack. We hypothesised that, if a bird is limited in its ability to morph its wings and adapt its wing shape to suit both flight modes, then a preference towards flapping flight optimization will be expected since this is the most energetically demanding flight mode. We tested this by studying a well-known flap-gliding species, the common swift, by measuring the wakes generated by two birds, one in gliding and one in flapping flight in a wind tunnel. We calculated span efficiency, the efficiency of lift production, and found that the flapping swift had consistently higher span efficiency than the gliding swift. This supports our hypothesis and suggests that even though swifts have been shown previously to increase their lift-to-drag ratio substantially when gliding, the wing morphology is tuned to be more aerodynamically efficient in generating lift during flapping. Since body drag can be assumed to be similar for both flapping and gliding, it follows that the higher total drag in flapping flight compared with gliding flight is primarily a consequence of an increase in wing profile drag due to the flapping motion, exceeding the reduction in induced drag.

The two-component afterglow of Swift GRB 050802

Science.gov (United States)

Oates, S. R.; de Pasquale, M.; Page, M. J.; Blustin, A. J.; Zane, S.; McGowan, K.; Mason, K. O.; Poole, T. S.; Schady, P.; Roming, P. W. A.; Page, K. L.; Falcone, A.; Gehrels, N.

2007-09-01

This paper investigates GRB 050802, one of the best examples of a Swift gamma-ray burst afterglow that shows a break in the X-ray light curve, while the optical counterpart decays as a single power law. This burst has an optically bright afterglow of 16.5 mag, detected throughout the 170-650nm spectral range of the Ultraviolet and Optical Telescope (UVOT) onboard Swift. Observations began with the X-ray Telescope and UVOT telescopes 286s after the initial trigger and continued for 1.2 ×106s. The X-ray light curve consists of three power-law segments: a rise until 420s, followed by a slow decay with α =0.63 +/-0.03 until 5000s, after which, the light curve decays faster with a slope of α3 =1.59 +/-0.03. The optical light curve decays as a single power law with αO =0.82 +/-0.03 throughout the observation. The X-ray data on their own are consistent with the break at 5000s being due to the end of energy injection. Modelling the optical to X-ray spectral energy distribution, we find that the optical afterglow cannot be produced by the same component as the X-ray emission at late times, ruling out a single-component afterglow. We therefore considered two-component jet models and find that the X-ray and optical emission is best reproduced by a model in which both components are energy injected for the duration of the observed afterglow and the X-ray break at 5000s is due to a jet break in the narrow component. This bright, well-observed burst is likely a guide for interpreting the surprising finding of Swift that bursts seldom display achromatic jet breaks.

The interaction of swift electrons with surface excitations

International Nuclear Information System (INIS)

Ritchie, R.H.; Tennessee Univ., Knoxville, TN

1992-01-01

For many decades swift electrons have comprised a powerful tool for the study of the dynamical properties of condensed matter. The development of this technique has involved much important physics. Here we sketch the historical background of the field and some important developments in theory and experiment. Possible directions for future research are indicated

Fronts between hexagons and squares in a generalized Swift-Hohenberg equation

DEFF Research Database (Denmark)

Kubstrup, Christian; Herrero, H.; Pérez-García, C.

1996-01-01

Pinning effects in domain walls separating different orientations in patterns in nonequilibrium systems, are studied. Usually; theoretical studies consider perfect structures, but in experiments, point defects, grain boundaries, etc., always appear. The aim of this paper is to perform an analysis...... of the stability of fronts between hexagons and squares in a generalized Swift-Hohenberg model equation. We focus the analysis on pinned fronts between domains with different symmetries by using amplitude equations and by considering the small-scale structure in the pattern. The conditions for pinning effects...... and stable fronts are determined. This study is completed with direct simulations of the generalized Swift-Hohenberg equation. The results agree qualitatively with recent observations in convection and in ferrofluid instabilities....

FY17 Accomplishments - Testing Facilities and Capabilities at SWiFT, SNL

Energy Technology Data Exchange (ETDEWEB)

Berg, Jonathan Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-10-01

The Scaled Wind Farm Technologies (SWiFT) facility operated by Sandia National Laboratories (SNL) has, in support of the Atmosphere to electrons (A2e) research program, acquired measurements of wind turbine wake dynamics under various atmospheric conditions and while interacting with a downstream wind turbine. SNL researchers, in collaboration with National Renewable Energy Laboratory (NREL) researchers, installed a customized LIDAR system created by the Technical University of Denmark (DTU) in one of the SWiFT wind turbines (Figure 1) and operated that turbine with intentional yaw-versus-winddirection misalignment to study the behavior of the turbine wake under numerous combinations of atmospheric conditions and turbine yaw offsets. The DTU-customized LIDAR provided detailed measurements of the wake’s shape and location at many distances downwind of the turbine (Figure 2). These measurements will benefit wind energy researchers looking to understand wind turbine wake behavior and improve modeling and simulation of wake dynamics, including the “wake steering” affect that is observed when turbine yaw offset is controlled. During the test campaign, two SWiFT wind turbines were operated at the same time to observe the influence of the turbines on each other as the wake of the upwind turbine was observed sweeping over and interacting with the downwind turbine.

Swift and Smart Decision Making: Heuristics that Work

Science.gov (United States)

Hoy, Wayne K.; Tarter, C. J.

2010-01-01

Purpose: The aim of this paper is to examine the research literature on decision making and identify and develop a set of heuristics that work for school decision makers. Design/methodology/approach: This analysis is a synthesis of the research on decision-making heuristics that work. Findings: A set of nine rules for swift and smart decision…

CEC natural analogue working group

International Nuclear Information System (INIS)

Come, B.; Chapman, N.A.

1986-01-01

The second meeting of the CEC Natural Analogue Working Group took place on June 17-19, 1986, hosted by the Swiss NAGRA in Interlaken (CH). A review of recent progress in natural analogue programmes was carried out, and complemented by detailed discussions about geomicrobiology, archaeological analogues, natural colloids, and use of analogues to increase confidence in safety assessments for radioactive waste disposal. A statement drafted by the Group, and the presentations made, are put together in this report

SOLID WASTE INTEGRATED FORECAST TECHNICAL (SWIFT) REPORT FY2005 THRU FY2035 VERSION 2005.0 VOLUME 1

Energy Technology Data Exchange (ETDEWEB)

BARCOT, R.A.

2005-04-13

The SWIFT Report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. This report is an annual update to the SWIFT 2004.1 report that was published in August 2004. The SWIFT Report is published in two volumes. SWIFT Volume II provides detailed analyses of the data, graphical representation, comparison to previous years, and waste generator specific information. The data contained in this report are the official data for solid waste forecasting. In this revision, the volume numbers have been switched to reflect the timing of their release. This particular volume provides the following data reports: (1) Summary volume data by DOE Office, company, and location; (2) Annual volume data by waste generator; (3) Annual waste specification record and physical waste form volume; (4) Radionuclide activities and dose-equivalent curies; and (5) Annual container type data by volume and count.

SOLID WASTE INTEGRATED FORECAST TECHNICAL (SWIFT) REPORT FY2005 THRU FY2035 VERSION 2005.0 VOLUME 1

International Nuclear Information System (INIS)

BARCOT, R.A.

2005-01-01

The SWIFT Report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. This report is an annual update to the SWIFT 2004.1 report that was published in August 2004. The SWIFT Report is published in two volumes. SWIFT Volume II provides detailed analyses of the data, graphical representation, comparison to previous years, and waste generator specific information. The data contained in this report are the official data for solid waste forecasting. In this revision, the volume numbers have been switched to reflect the timing of their release. This particular volume provides the following data reports: (1) Summary volume data by DOE Office, company, and location; (2) Annual volume data by waste generator; (3) Annual waste specification record and physical waste form volume; (4) Radionuclide activities and dose-equivalent curies; and (5) Annual container type data by volume and count

Defect production and subsequent effects induced by electronic energy loss of swift heavy ion

International Nuclear Information System (INIS)

Hou Mingdong; Liu Jie; Sun Youmei; Yin Jingmin; Yao Huijun; Duan Jinglai; Mo Dan; Zhang Ling; Chen Yanfeng; Chinese Academy of Sciences, Beijing

2008-01-01

Swift heavy ion in matter is one of forfront fields of nuclear physics in the world. A series of new phenomena were discovered in recent years. The history and sta- tus on the development of this field were reviewed. Electronic energy loss effects induced by swift heavy ion irradiation, such as defect production and evolution, ion latent track formation, phase transformation and anisotropy plastic deformation were introduced emphatically. A trend of future investigation was explored. (authors)

Finite element prediction of the swift effect based on Taylor-type polycrystal plasticity models

OpenAIRE

Duchene, Laurent; Delannay, L.; Habraken, Anne

2004-01-01

This paper describes the main concepts of the stress-strain interpolation model that has been implemented in the non-linear finite element code Lagamine. This model consists in a local description of the yield locus based on the texture of the material through the full constraints Taylor’s model. The prediction of the Swift effect is investigated: the influence of the texture evolution is shown up. The LAMEL model is also investigated for the Swift effect prediction. Peer reviewed

NASA's Swift Satellite Catches First Supernova in The Act of Exploding

Science.gov (United States)

2008-05-01

GREENBELT, Md.- Thanks to a fortuitous observation with NASA’s Swift satellite, astronomers for the first time have caught a star in the act of exploding. Astronomers have previously observed thousands of stellar explosions, known as supernovae, but they have always seen them after the fireworks were well underway. "For years we have dreamed of seeing a star just as it was exploding, but actually finding one is a once in a lifetime event," says team leader Alicia Soderberg, a Hubble and Carnegie-Princeton Fellow at Princeton University in Princeton, N.J. "This newly born supernova is going to be the Rosetta stone of supernova studies for years to come." A typical supernova occurs when the core of a massive star runs out of nuclear fuel and collapses under its own gravity to form an ultradense object known as a neutron star. The newborn neutron star compresses and then rebounds, triggering a shock wave that plows through the star’s gaseous outer layers and blows the star to smithereens. Astronomers thought for nearly four decades that this shock "break-out" will produce bright X-ray emission lasting a few minutes. X-ray Image X-ray Images But until this discovery, astronomers have never observed this signal. Instead, they have observed supernovae brightening days or weeks later, when the expanding shell of debris is energized by the decay of radioactive elements forged in the explosion. "Seeing the shock break-out in X-rays can give a direct view of the exploding star in the last minutes of its life and also provide a signpost to which astronomers can quickly point their telescopes to watch the explosion unfold," says Edo Berger, a Carnegie-Princeton Fellow at Princeton University. Soderberg's discovery of the first shock breakout can be attributed to luck and Swift's unique design. On January 9, 2008, Soderberg and Berger were using Swift to observe a supernova known as SN 2007uy in the spiral galaxy NGC 2770, located 90 million light-years from Earth in the

Evidence of soft bound behaviour in analogue memristive devices for neuromorphic computing.

Science.gov (United States)

Frascaroli, Jacopo; Brivio, Stefano; Covi, Erika; Spiga, Sabina

2018-05-08

The development of devices that can modulate their conductance under the application of electrical stimuli constitutes a fundamental step towards the realization of synaptic connectivity in neural networks. Optimization of synaptic functionality requires the understanding of the analogue conductance update under different programming conditions. Moreover, properties of physical devices such as bounded conductance values and state-dependent modulation should be considered as they affect storage capacity and performance of the network. This work provides a study of the conductance dynamics produced by identical pulses as a function of the programming parameters in an HfO 2 memristive device. The application of a phenomenological model that considers a soft approach to the conductance boundaries allows the identification of different operation regimes and to quantify conductance modulation in the analogue region. Device non-linear switching kinetics is recognized as the physical origin of the transition between different dynamics and motivates the crucial trade-off between degree of analog modulation and memory window. Different kinetics for the processes of conductance increase and decrease account for device programming asymmetry. The identification of programming trade-off together with an evaluation of device variations provide a guideline for the optimization of the analogue programming in view of hardware implementation of neural networks.

The impact parameter dependence of swift electron-matter interactions

International Nuclear Information System (INIS)

Ritchie, R.H.

1988-01-01

In quantal collision theories, momentum and energy are usually taken to be good quantal variables. Classical collision theory, on the other hand, uses position and time to describe interactions between a probe and a target. In modern physics one may wish to express quantal theories in terms of spacelike variables. For example, experiments are now common in which one measures, by means of a narrowly focused beam of swift electrons, the distribution in energy of losses experienced in a very small region of space. Also, in experiments with channeled ions, and in microdosimetry, one is interested in the spatial coherence of unlocalized excitations created by swift ions and electrons, and their ultimate localization through transfer of energy to, e.g., single-particle excitations. In this lecture the author describes work, done in part in collaboration with Professor Howie, on some aspects of the spatial dependence of inelastic interactions between a charged particle and a condensed matter target. 6 refs., 1 fig

Electron emission from solids induced by swift heavy ions

International Nuclear Information System (INIS)

Xiao Guoqing

2000-01-01

The recent progresses in experimental and theoretical studies of the collision between swift heavy ion and solids as well as electron emission induced by swift heavy ion in solids were briefly reviewed. Three models, Coulomb explosion, thermal spike and repulsive long-lived states, for interpreting the atomic displacements stimulated by the electronic energy loss were discussed. The experimental setup and methods for measuring the electron emission from solids were described. The signification deviation from a proportionality between total electron emission yields and electronic stopping power was found. Auger-electron and convoy-electron spectra are thought to be a probe for investigating the microscopic production mechanisms of the electronic irradiation-damage. Electron temperature and track potential at the center of nuclear tracks in C and polypropylene foils induced by 5 MeV/u heavy ions, which are related to the electronic excitation density in metals and insulators respectively, were extracted by measuring the high resolution electron spectra

Observational differences between Swift GRB classes

International Nuclear Information System (INIS)

Balazs, L. G.; Horvath, I.; Bagoly, Zs.; Szecsi, D.; Veres, P.

2011-01-01

There are accumulating evidences that GRBs have an intermediate group, beside the short and long classes. Based on the observational data available in the Swift table we compared the observational γ and X ray properties of GRBs making use the discriminant analysis of the multivariate mathematical statistics. The analysis resulted in two canonical discriminating functions giving the maximum separation between the groups. The first discriminating function is dominated by the γ and X-ray fluence while the second one is almost identical with the photon index.

Swift UVOT Grism Observations of Nearby Type Ia Supernovae - I. Observations and Data Reduction

Science.gov (United States)

Pan, Y.-C.; Foley, R. J.; Filippenko, A. V.; Kuin, N. P. M.

2018-05-01

Ultraviolet (UV) observations of Type Ia supernovae (SNe Ia) are useful tools for understanding progenitor systems and explosion physics. In particular, UV spectra of SNe Ia, which probe the outermost layers, are strongly affected by the progenitor metallicity. In this work, we present 120 Neil Gehrels Swift Observatory UV spectra of 39 nearby SNe Ia. This sample is the largest UV (λ Ia to date, doubling the number of UV spectra and tripling the number of SNe with UV spectra. The sample spans nearly the full range of SN Ia light-curve shapes (Δm15(B) ≈ 0.6-1.8 mag). The fast turnaround of Swift allows us to obtain UV spectra at very early times, with 13 out of 39 SNe having their first spectra observed ≳ 1 week before peak brightness and the earliest epoch being 16.5 days before peak brightness. The slitless design of the Swift UV grism complicates the data reduction, which requires separating SN light from underlying host-galaxy light and occasional overlapping stellar light. We present a new data-reduction procedure to mitigate these issues, producing spectra that are significantly improved over those of standard methods. For a subset of the spectra we have nearly simultaneous Hubble Space Telescope UV spectra; the Swift spectra are consistent with these comparison data.

Fourteen Years of Education and Public Outreach for the Swift Gamma-ray Burst Explorer Mission

OpenAIRE

Cominsky, Lynn; McLin, Kevin; Simonnet, Aurore; Team, the Swift E/PO

2014-01-01

The Sonoma State University (SSU) Education and Public Outreach (E/PO) group leads the Swift Education and Public Outreach program. For Swift, we have previously implemented broad efforts that have contributed to NASA's Science Mission Directorate E/PO portfolio across many outcome areas. Our current focus is on highly-leveraged and demonstrably successful activities, including the wide-reaching Astrophysics Educator Ambassador program, and our popular websites: Epo's Chronicles and the Gamma...

Achieving swift equilibration of a Brownian particle using flow-fields

Science.gov (United States)

Patra, Ayoti; Jarzynski, Christopher

Can a system be driven to a targeted equilibrium state on a timescale that is much shorter than its natural equilibration time? In a recent experiment, the swift equilibration of an overdamped Brownian particle was achieved by use of an appropriately designed, time-dependent optical trap potential. Motivated by these results, we develop a general theoretical approach for guiding an ensemble of Brownian particles to track the instantaneous equilibrium distribution of a desired potential U (q , t) . In our approach, we use flow-fields associated with the parametric evolution of the targeted equilibrium state to construct an auxiliary potential U (q , t) , such that dynamics under the composite potential U (t) + U (t) achieves the desired evolution. Our results establish a close connection between the swift equilibration of Brownian particles, quantum shortcuts to adiabaticity, and the dissipationless driving of a classical, Hamiltonian system.

The Effects of Incentives on Visual-Spatial Working Memory in Children with Attention-Deficit/Hyperactivity Disorder

Science.gov (United States)

Shiels, Keri; Hawk, Larry W., Jr.; Lysczek, Cynthia L.; Tannock, Rosemary; Pelham, William E., Jr.; Spencer, Sarah V.; Gangloff, Brian P.; Waschbusch, Daniel A.

2008-01-01

Working memory is one of several putative core neurocognitive processes in attention-deficit/hyperactivity disorder (ADHD). The present work seeks to determine whether visual-spatial working memory is sensitive to motivational incentives, a laboratory analogue of behavioral treatment. Participants were 21 children (ages 7-10) with a diagnosis of…

[Jonathan Swift's asylum in Dublin--Ireland's introduction to institutional psychiatry 250 years ago].

Science.gov (United States)

Reuber, M

1995-09-01

250 years ago, the satirical writer and clergyman Jonathan Swift from Dublin (1667-1745) founded the first Irish lunatic asylum. Rejecting the theories put forward by the English philosopher Thomas Hobbes and the doctor Thomas Willis, he was influenced by the ideas of the Scottish doctor and the "enlightened" thinker John Locke. Swift's St. Patrick's Hospital did not, however, realise a new philosophical concept: architecture and therapeutic approach of the new institution were clearly modelled on the much older Hospital of St. Mary of Bethlehem ( = Bedlam). Despite its conservative conceptual basis, the first institution dedicated to the mentally ill and intellectually subnormal in Ireland became a starting point for the apparantly unstoppable expansion of the, at one time, most comprehensive asylum system in the world. After Swift's Hospital had been enlarged twice at the tax-payers' expense (1778, 1793), the administration decided to relieve the institution by erecting the Richmond Asylum (1810), the first public asylum in Ireland. When this establishment also became overcrowded, in 1817, legislation was passed which led to the establishment of the oldest system of public asylums in Europe.

INTEGRAL detection of SWIFT J2037.2+4151

DEFF Research Database (Denmark)

Westergaard, Niels Jørgen Stenfeldt; Budtz-Jørgensen, Carl; Chenevez, Jérôme

2006-01-01

The source detected by SWIFT (ATEL #853) was independently found in archived JEM-X public data in 5 pointings covering 18200s between 2004-07-19, 19:14 UTC and 2004-07-20, 03:27 UTC. Positioned within 1.2 degrees of Cyg X-3 it has been inside the JEM-X field-of-view more than 400 times with an of...

OpenStack Swift as Multi-Region Eventual Consistency Storage for ownCloud Primary Storage

CERN Multimedia

CERN. Geneva

2014-01-01

As more users adopt AARNet’s CloudStor Plus offering within Australia, interim solutions deployed to overcome failures of various distributed replicated storage technologies haven’t kept pace with the growth in data volume. AARNet’s original design goal of user proximal data storage, combined with national and even international data replication for redundancy reasons continues to be a key driver for design choices. AARNet’s national network is over 90ms from end to end, and accommodating this has been a key issue with numerous software solutions, hindering attempts to provide both original design goals in a reliable real-time manner. With the addition of features to the ownCloud software allowing primary data storage on OpenStack Swift, AARNet has chosen to deploy Swift in a nation spanning multi-region ring to take advantage of Swift’s eventual consistency capabilities and the local region quorum functionality for fast writes. The scaling capability of Swift resolves the twin problems of geogr...

Roles of NO signaling in long-term memory formation in visual learning in an insect.

Directory of Open Access Journals (Sweden)

Yukihisa Matsumoto

Full Text Available Many insects exhibit excellent capability of visual learning, but the molecular and neural mechanisms are poorly understood. This is in contrast to accumulation of information on molecular and neural mechanisms of olfactory learning in insects. In olfactory learning in insects, it has been shown that cyclic AMP (cAMP signaling critically participates in the formation of protein synthesis-dependent long-term memory (LTM and, in some insects, nitric oxide (NO-cyclic GMP (cGMP signaling also plays roles in LTM formation. In this study, we examined the possible contribution of NO-cGMP signaling and cAMP signaling to LTM formation in visual pattern learning in crickets. Crickets that had been subjected to 8-trial conditioning to associate a visual pattern with water reward exhibited memory retention 1 day after conditioning, whereas those subjected to 4-trial conditioning exhibited 30-min memory retention but not 1-day retention. Injection of cycloheximide, a protein synthesis inhibitor, into the hemolymph prior to 8-trial conditioning blocked formation of 1-day memory, whereas it had no effect on 30-min memory formation, indicating that 1-day memory can be characterized as protein synthesis-dependent long-term memory (LTM. Injection of an inhibitor of the enzyme producing an NO or cAMP prior to 8-trial visual conditioning blocked LTM formation, whereas it had no effect on 30-min memory formation. Moreover, injection of an NO donor, cGMP analogue or cAMP analogue prior to 4-trial conditioning induced LTM. Induction of LTM by an NO donor was blocked by DDA, an inhibitor of adenylyl cyclase, an enzyme producing cAMP, but LTM induction by a cAMP analogue was not impaired by L-NAME, an inhibitor of NO synthase. The results indicate that cAMP signaling is downstream of NO signaling for visual LTM formation. We conclude that visual learning and olfactory learning share common biochemical cascades for LTM formation.

Seasonal food habits of swift fox (Vulpes velox) in cropland and rangeland landscapes in western Kansas

Science.gov (United States)

Sovada, M.A.; Roy, C.C.; Telesco, D.J.

2001-01-01

Food habits of swift foxes (Vulpes velox) occupying two distinct landscapes (dominated by cropland versus rangeland) in western Kansas were determined by analysis of scats collected in 1993 and 1996. Frequencies of occurrence of prey items in scats were compared between cropland and rangeland areas by season. Overall, the most frequently occurring foods of swift foxes were mammals (92% of all scats) and arthropods (87%), followed by birds (24%), carrion (23%), plants (15%) and reptiles (4%). No differences were detected between landscapes for occurrence of mammals, arthropods or carrion in any season (P ≥ 0.100). Plants, specifically commercial sunflower seeds, were consumed more frequently in cropland than in rangeland in spring (P = 0.004) and fall (P = 0.001). Birds were more common in the swift fox diet in cropland than in rangeland during the fall (P = 0.008), whereas reptiles occurred more frequently in the diet in rangeland than in cropland during spring (P = 0.042). Variation in the diet of the swift fox between areas was most likely due to its opportunistic foraging behavior, resulting in a diet that closely links prey use with availability.

Discovery of the Accretion-Powered Millisecond Pulsar SWIFT 51756.9-2508 with a Low-Mass Companion

Science.gov (United States)

Krimm, H.A.; Markwardt, C.B.; Deloye, C.J.; Romano, P.; Chakrabarty, S.; Campana. S.; Cummings, J.C.; Galloway, D.K.; Gehrels, N.; Hartman, J.M.;

CEC Natural Analogue Working Group

International Nuclear Information System (INIS)

Come, B.; Chapman, N.A.

1989-01-01

The central theme for the third meeting of the CEC analogue working group was ''How can analogue data be used for performance assessments, both in support of the results and for presentation to the public''. This report puts together the most recent achievements in this field, together with a review of on-going natural analogue programmes

The Society for Worldwide Interbank Financial Telecommunication (SWIFT) : Cooperative governance for network innovation, standards, and community

OpenAIRE

Scott, Suzan V; Zachariadis, Markos

2014-01-01

This book traces the history and development of a mutual organization in the financial sector called SWIFT, the Society for Worldwide Interbank Financial Telecommunication. Over the last 40 years, SWIFT has served the financial services sector as proprietary communications platform, provider of products and services, standards developer, and conference organizer (Sibos). Founded to create efficiencies by replacing telegram and telex (or “wires”) for international payments, SWIF...

SOLID WASTE INTEGRATED FORECAST TECHNICAL (SWIFT) REPORT FY2003 THRU FY2046 VERSION 2003.1 VOLUME 1 [SECTION 1 and 2

International Nuclear Information System (INIS)

BARCOT, R.A.

2003-01-01

The SWIFT Report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. This SWIFT report is a mid-year update to the SWIFT 2003.0 report that was published in January 2003. The SWIFT Report is published in two volumes. SWIFT Volume II provides detailed analyses of the data, graphical representation, comparison to previous years, and waste generator specific information. The data contained in this report are the official data for solid waste forecasting. In this revision, the volume numbers have been switched to reflect the timing of their release. This particular volume provides the following data reports: Summary volume data by DOE Office, company, and location; Annual volume data by waste generator; Annual waste specification record and physical waste form volume; Radionuclide activities and dose-equivalent curies; and Annual container type data by volume and count

Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

DEFF Research Database (Denmark)

Martin-Bertelsen, Birte; Korsholm, Karen Smith; Christensen, Dennis

2016-01-01

responses. In the present study, we investigated the supramolecular structure and in vivo adjuvant activity of dispersions based on binary mixtures of DDA and an array of synthetic MMG-1 analogues (MMG- 2/3/5/6) displaying longer (MMG-2) or shorter (MMG-3) alkyl chain lengths, or polar headgroup (MMG-5...... for DDA:MMG-3, depending on the DDA:MMG molar ratio. The studies also showed that ULVs were formed, regardless of the structural characteristics of the neat MMG analogues in excess buffer [lamellar (MMG-1/2/5) or inverse hexagonal (MMG-3/6) phases]. Immunization of mice with a chlamydia antigen surface......-adsorbed to DDA:MMG-1/3/6 dispersions revealed that all tested adjuvants were immunoactive and induced strong Th1 and Th17 responses with a potential for a central effector memory profile. The MMG-1 and MMG-6 analogues were equally immunoactive in vivo upon incorporation into DDA liposomes, despite the reported...

Fermi and Swift Gamma-Ray Burst Afterglow Population Studies

Science.gov (United States)

Racusin, Judith L.; Oates, S. R.; Schady, P.; Burrows, D. N.; dePasquale, M.; Donato, D.; Gehrels, N.; Koch, S.; McEnery, J.; Piran, T.;

Analogue alternative the electronic analogue computer in Britain and the USA, 1930-1975

CERN Document Server

Small, James S

2013-01-01

We are in the midst of a digital revolution - until recently, the majority of appliances used in everyday life have been developed with analogue technology. Now, either at home or out and about, we are surrounded by digital technology such as digital 'film', audio systems, computers and telephones. From the late 1940s until the 1970s, analogue technology was a genuine alternative to digital, and the two competing technologies ran parallel with each other. During this period, a community of engineers, scientists, academics and businessmen continued to develop and promote the analogue computer.

Discovery and Evolution of the New Black Hole Candidate Swift J1539.2-6227 During Its 2008 Outburst

Science.gov (United States)

Krimm, H. A.; Tomsick, J. A.; Markwardt, C. B.; Brocksopp, C.; Grise, F.; Kaaret, P.; Romano, P.

2010-01-01

We report on the discovery by the Swift Gamma-Ray Burst Explorer of the black hole candidate Swift J1539.2-6227 and the subsequent course of an outburst beginning in November 2008 and lasting at least seven months. The source was discovered during normal observations with the Swift Burst Alert Telescope (BAT) on 2008 November 25. An extended observing campaign with the Rossi X-Ray Timing Explorer (RXTE) and Swift provided near-daily coverage over 176 days, giving us a rare opportunity to track the evolution of spectral and timing parameters with fine temporal resolution through a series of spectral states. The source was first detected in a hard state during which strong low-frequency quasiperiodic oscillations (QPOs) were detected. The QPOs persisted for about 35 days and a signature of the transition from the hard to soft intermediate states was seen in the timing data. The source entered a short-lived thermal state about 40 days after the start of the outburst. There were variations in spectral hardness as the source flux declined and returned to a hard state at the end of the outburst. The progression of spectral states and the nature of the timing features provide strong evidence that Swift J1539.2-6227 is a candidate black hole in a low-mass X-ray binary system.

Time domain astronomy with Swift and Fermi | Gehrels | Rwanda ...

African Journals Online (AJOL)

Swift and Fermi are unveiling an unexpectedly rich tapestry of behavior in the transient γ−ray sky. Sources which were already known to be transient − such as pulsars, gamma-ray bursts, and blazars − have been studied in ever-increasing detail. For example, Fermi/LAT has detected 117 pulsars of which 56 are new.

Detecting swift fox: Smoked-plate scent stations versus spotlighting

Science.gov (United States)

Daniel W. Uresk; Kieth E. Severson; Jody Javersak

2003-01-01

We compared two methods of detecting presence of swift fox: smoked-plate scent stations and spotlight counts. Tracks were counted on ten 1-mile (1.6-km) transects with bait/tracking plate stations every 0.1 mile (0.16 km). Vehicle spotlight counts were conducted on the same transects. Methods were compared with Spearman's rank order correlation. Repeated measures...

Structural modifications of swift heavy ion irradiated PEN probed by optical and thermal measurements

International Nuclear Information System (INIS)

Devgan, Kusum; Singh, Lakhwant; Samra, Kawaljeet Singh

2013-01-01

Highlights: • The present paper reports the effect of swift heavy ion irradiation on Polyethylene Naphthalate (PEN). • Swift heavy ion irradiation introduces structural modification and degradation of PEN at different doses. • Lower irradiation doses in PEN result in modification of structural properties and higher doses lead to complete degradation. • Strong correlation between structural, optical, and thermal properties. - Abstract: The effects of swift heavy ion irradiation on the structural characteristics of Polyethylene naphthalate (PEN) were studied. Samples were irradiated in vacuum at room temperature by lithium (50 MeV), carbon (85 MeV), nickel (120 MeV) and silver (120 MeV) ions with the fluence in the range of 1×10 11 –3×10 12 ions cm −2 . Ion induced changes were analyzed using X-ray diffraction (XRD), Fourier transform infra red (FT-IR), UV–visible spectroscopy, thermo-gravimetric analysis (TGA) and differential scanning calorimetry (DSC) techniques. Cross-linking was observed at lower doses resulting in modification of structural properties, however higher doses lead to the degradation of the investigated polymeric samples

In-flight calibration of the Swift XRT Point Spread Function

International Nuclear Information System (INIS)

Moretti, A.; Campana, S.; Chincarini, G.; Covino, S.; Romano, P.; Tagliaferri, G.; Capalbi, M.; Giommi, P.; Perri, M.; Cusumano, G.; La Parola, V.; Mangano, V.; Mineo, T.

2006-01-01

The Swift X-ray Telescope (XRT) is designed to make astrometric, spectroscopic and photometric observations of the X-ray emission from Gamma-ray bursts and their afterglows, in the energy band 0.2-10 keV. Here we report the results of the analysis of Swift XRT Point Spread Function (PSF) as measured in the first four months of the mission during the instrument calibration phase. The analysis includes the study of the PSF of different point-like sources both on-axis and off-axis with different spectral properties. We compare the in-flight data with the expectations from the on-ground calibration. On the basis of the calibration data we built an analytical model to reproduce the PSF as a function of the energy and the source position within the detector which can be applied in the PSF correction calculation for any extraction region geometry. All the results of this study are implemented in the standard public software

Learning iOS 8 game development using Swift

CERN Document Server

Shekar, Siddharth

2015-01-01

This book is for novices as well as proficient game developers who want to learn more about game development using Swift. If you are from a 2D game development background and would like to learn the basics of 3D game development, this book is for you. Additionally, if you want to learn the basics of graphics programming and shaders, this book will be a good starting point.

Natural Analogue Synthesis Report

Energy Technology Data Exchange (ETDEWEB)

A. M. Simmons

2002-05-01

The purpose of this report is to present analogue studies and literature reviews designed to provide qualitative and quantitative information to test and provide added confidence in process models abstracted for performance assessment (PA) and model predictions pertinent to PA. This report provides updates to studies presented in the ''Yucca Mountain Site Description'' (CRWMS M and O 2000 [151945], Section 13) and new examples gleaned from the literature, along with results of quantitative studies conducted specifically for the Yucca Mountain Site Characterization Project (YMP). The intent of the natural analogue studies was to collect corroborative evidence from analogues to demonstrate additional understanding of processes expected to occur during postclosure at a potential Yucca Mountain repository. The report focuses on key processes by providing observations and analyses of natural and anthropogenic (human-induced) systems to improve understanding and confidence in the operation of these processes under conditions similar to those that could occur in a nuclear waste repository. The process models include those that represent both engineered and natural barrier processes. A second purpose of this report is to document the various applications of natural analogues to geologic repository programs, focusing primarily on the way analogues have been used by the YMP. This report is limited to providing support for PA in a confirmatory manner and to providing corroborative inputs for process modeling activities. Section 1.7 discusses additional limitations of this report. Key topics for this report are analogues to emplacement drift degradation, waste form degradation, waste package degradation, degradation of other materials proposed for the engineered barrier, seepage into drifts, radionuclide flow and transport in the unsaturated zone (UZ), analogues to coupled thermal-hydrologic-mechanical-chemical processes, saturated zone (SZ) transport

NATURAL ANALOGUE SYNTHESIS REPORT

International Nuclear Information System (INIS)

Simmons, A.M.

2004-01-01

The purpose of this report is to present analogue studies and literature reviews designed to provide qualitative and quantitative information to test and provide added confidence in process models abstracted for performance assessment (PA) and model predictions pertinent to PA. This report provides updates to studies presented in the Yucca Mountain Site Description (CRWMS M and O 2000 [151945], Section 13) and new examples gleaned from the literature along with results of quantitative studies conducted specifically for the Yucca Mountain Project (YMP). The intent of the natural analogue studies was to collect corroborative evidence from analogues to demonstrate additional understanding of processes expected to occur during postclosure at a potential Yucca Mountain repository. The report focuses on key processes by providing observations and analyses of natural and anthropogenic (human-induced) systems to improve understanding and confidence in the operation of these processes under conditions similar to those that could occur in a nuclear waste repository. The process models include those that represent both engineered and natural barrier processes. A second purpose of this report is to document the various applications of natural analogues to geologic repository programs, focusing primarily on the way analogues have been used by the YMP. This report is limited to providing support for PA in a confirmatory manner and to providing corroborative inputs for process modeling activities. Section 1.7 discusses additional limitations of this report. Key topics for this report are analogues to emplacement-drift degradation, waste-form degradation, waste-package degradation, degradation of other materials proposed for the engineered barrier, seepage into drifts, radionuclide flow and transport in the unsaturated zone (UZ), analogues to coupled thermal-hydrologic-mechanical-chemical processes, saturated-zone (SZ) transport, impact of radionuclide release on the biosphere

Count out your intrusions: Effects of verbal encoding on intrusive memories

NARCIS (Netherlands)

Krans, J.; Näring, G.W.B.; Becker, E.S.

2009-01-01

Peri-traumatic information processing is thought to affect the development of intrusive trauma memories. This study aimed to replicate and improve the study by Holmes, Brewin, and Hennessy (2004, Exp. 3) on the role of peri-traumatic verbal processing in analogue traumatic intrusion development.

VizieR Online Data Catalog: X-ray/UV Swift monitoring of NGC 4151 (Edelson+, 2017)

Science.gov (United States)

Edelson, R.; Gelbord, J.; Cackett, E.; Connolly, S.; Done, C.; Fausnaugh, M.; Gardner, E.; Gehrels, N.; Goad, M.; Horne, K.; McHardy, I.; Peterson, B. M.; Vaughan, S.; Vestergaard, M.; Breeveld, A.; Barth, A. J.; Bentz, M.; Bottorff, M.; Brandt, W. N.; Crawford, S. M.; Bonta, E. D.; Emmanoulopoulos, D.; Evans, P.; Jaimes, R. F.; Filippenko, A. V.; Ferland, G.; Grupe, D.; Joner, M.; Kennea, J.; Korista, K. T.; Krimm, H. A.; Kriss, G.; Leonard, D. C.; Mathur, S.; Netzer, H.; Nousek, J.; Page, K.; Romero-Colmenero, E.; Siegel, M.; Starkey, D. A.; Treu, T.; Vogler, H. A.; Winkler, H.; Zheng, W.

2017-11-01

During 2016 February 20 through April 29, Swift executed an intensive monitoring campaign on NGC 4151, consisting of 319 separate visits of at least 120s, an average of nearly five visits per day. These Swift observations were coordinated with intensive monitoring with numerous ground-based telescopes including the Las Cumbres Observatory Global Telescope network and the Liverpool Telescope at La Palma. Those data will be presented in subsequent papers (K. Horne et al. 2017, in preparation; M. Goad et al. 2017, in preparation). (3 data files).

The new X-ray transient Swift J174805.3-244637 in Terzan 5 is a neutron star LMXB

NARCIS (Netherlands)

Altamirano, D.; Wijnands, R.; Heinke, C.O.; Sivakoff, G.R.; Pooley, D.

2012-01-01

We report on the ongoing monitoring Swift observations of the X-ray transient Swift J174805.3-244637 (ATEL #4249, #4242) in the globular cluster Terzan 5. During an observation taken on July 17th, 2012, we detect a Type-I X-ray burst in a ~950 seconds long observation which started at 20:54:00 UT.

XMM-Newton and Swift spectroscopy of the newly discovered very faint X-ray transient IGR J17494-3030

NARCIS (Netherlands)

Armas Padilla, M.; Wijnands, R.; Degenaar, N.

2013-01-01

A growing group of low-mass X-ray binaries are found to be accreting at very faint X-ray luminosities of <1036 erg s−1 (2-10 keV). One such system is the new X-ray transient IGR J17494-3030. We present Swift and XMM-Newton observations obtained during its 2012 discovery outburst. The Swift

X-ray and UV observations of Nova Mus 2018 with Swift

Science.gov (United States)

Nelson, Thomas; Mukai, Koji; Chomiuk, Laura; Li, Kwan-Kok; Kawash, Adam; Sokoloski, J. L.; Rupen, Michael; Linford, Justin; Mioduszewski, Amy

2018-01-01

We observed Nova Mus 2018 (PNV J11261220-6531086) with the Neil Gehrels Swift Observatory on 2018 January 21, 18 days after the initial rapid rise to V=8.8 on 2018 January 3.24 (see link below for more details).

PCA/INCREMENT MEMORY interface for analog processors on-line with PC-XT/AT IBM

International Nuclear Information System (INIS)

Biri, S.; Buttsev, V.S.; Molnar, J.; Samojlov, V.N.

1989-01-01

The functional and operational descriptions on PCA/INCREMENT MEMORY interface are discussed. The following is solved with this unit: connection between the analogue signal processor and PC, nuclear spectrum acquisition up to 2 24 -1 counts/channel using increment or decrement method, data read/write from or to memory via data bus PC during the spectrum acquisition. Dual ported memory organization is 4096x24 bit, increment cycle time at 4.77 MHz system clock frequency is 1.05 μs. 6 refs.; 2 figs

SWIFT X-RAY OBSERVATIONS OF CLASSICAL NOVAE. II. THE SUPER SOFT SOURCE SAMPLE

Energy Technology Data Exchange (ETDEWEB)

Schwarz, Greg J. [American Astronomical Society, 2000 Florida Avenue, NW, Suite 400, Washington, DC 20009-1231 (United States); Ness, Jan-Uwe [XMM-Newton Science Operations Centre, ESAC, Apartado 78, 28691 Villanueva de la Canada, Madrid (Spain); Osborne, J. P.; Page, K. L.; Evans, P. A.; Beardmore, A. P. [Department of Physics and Astronomy, University of Leicester, Leicester LE1 7RH (United Kingdom); Walter, Frederick M. [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794-3800 (United States); Andrew Helton, L. [SOFIA Science Center, USRA, NASA Ames Research Center, M.S. N211-3, Moffett Field, CA 94035 (United States); Woodward, Charles E. [Minnesota Institute of Astrophysics, 116 Church Street S.E., University of Minnesota, Minneapolis, MN 55455 (United States); Bode, Mike [Astrophysics Research Institute, Liverpool John Moores University, Birkenhead CH41 1LD (United Kingdom); Starrfield, Sumner [School of Earth and Space Exploration, Arizona State University, P.O. Box 871404, Tempe, AZ 85287-1404 (United States); Drake, Jeremy J., E-mail: Greg.Schwarz@aas.org [Smithsonian Astrophysical Observatory, 60 Garden Street, MS 3, Cambridge, MA 02138 (United States)

2011-12-01

The Swift gamma-ray burst satellite is an excellent facility for studying novae. Its rapid response time and sensitive X-ray detector provides an unparalleled opportunity to investigate the previously poorly sampled evolution of novae in the X-ray regime. This paper presents Swift observations of 52 Galactic/Magellanic Cloud novae. We included the X-Ray Telescope (0.3-10 keV) instrument count rates and the UltraViolet and Optical Telescope (1700-8000 A) filter photometry. Also included in the analysis are the publicly available pointed observations of 10 additional novae the X-ray archives. This is the largest X-ray sample of Galactic/Magellanic Cloud novae yet assembled and consists of 26 novae with Super Soft X-ray emission, 19 from Swift observations. The data set shows that the faster novae have an early hard X-ray phase that is usually missing in slower novae. The Super Soft X-ray phase occurs earlier and does not last as long in fast novae compared to slower novae. All the Swift novae with sufficient observations show that novae are highly variable with rapid variability and different periodicities. In the majority of cases, nuclear burning ceases less than three years after the outburst begins. Previous relationships, such as the nuclear burning duration versus t{sub 2} or the expansion velocity of the eject and nuclear burning duration versus the orbital period, are shown to be poorly correlated with the full sample indicating that additional factors beyond the white dwarf mass and binary separation play important roles in the evolution of a nova outburst. Finally, we confirm two optical phenomena that are correlated with strong, soft X-ray emission which can be used to further increase the efficiency of X-ray campaigns.

SWIFT X-RAY OBSERVATIONS OF CLASSICAL NOVAE. II. THE SUPER SOFT SOURCE SAMPLE

International Nuclear Information System (INIS)

Schwarz, Greg J.; Ness, Jan-Uwe; Osborne, J. P.; Page, K. L.; Evans, P. A.; Beardmore, A. P.; Walter, Frederick M.; Andrew Helton, L.; Woodward, Charles E.; Bode, Mike; Starrfield, Sumner; Drake, Jeremy J.

2011-01-01

The Swift gamma-ray burst satellite is an excellent facility for studying novae. Its rapid response time and sensitive X-ray detector provides an unparalleled opportunity to investigate the previously poorly sampled evolution of novae in the X-ray regime. This paper presents Swift observations of 52 Galactic/Magellanic Cloud novae. We included the X-Ray Telescope (0.3-10 keV) instrument count rates and the UltraViolet and Optical Telescope (1700-8000 Å) filter photometry. Also included in the analysis are the publicly available pointed observations of 10 additional novae the X-ray archives. This is the largest X-ray sample of Galactic/Magellanic Cloud novae yet assembled and consists of 26 novae with Super Soft X-ray emission, 19 from Swift observations. The data set shows that the faster novae have an early hard X-ray phase that is usually missing in slower novae. The Super Soft X-ray phase occurs earlier and does not last as long in fast novae compared to slower novae. All the Swift novae with sufficient observations show that novae are highly variable with rapid variability and different periodicities. In the majority of cases, nuclear burning ceases less than three years after the outburst begins. Previous relationships, such as the nuclear burning duration versus t 2 or the expansion velocity of the eject and nuclear burning duration versus the orbital period, are shown to be poorly correlated with the full sample indicating that additional factors beyond the white dwarf mass and binary separation play important roles in the evolution of a nova outburst. Finally, we confirm two optical phenomena that are correlated with strong, soft X-ray emission which can be used to further increase the efficiency of X-ray campaigns.

Swift Heavy Ions in Matter

Science.gov (United States)

Rothard, Hermann; Severin, Daniel; Trautmann, Christina

2015-12-01

The present volume contains the proceedings of the Ninth International Symposium on Swift Heavy Ions in Matter (SHIM). This conference was held in Darmstadt, from 18 to 21 May 2015. SHIM is a triennial series, which started about 25 years ago by a joint initiative of CIRIL - Caen and GSI - Darmstadt, with the aim of promoting fundamental and applied interdisciplinary research in the field of high-energy, heavy-ion interaction processes with matter. SHIM was successively organized in Caen (1989), Bensheim (1992), Caen (1995), Berlin (1998), Catania (2002), Aschaffenburg (2005), Lyon (2008), and Kyoto (2012). The conference attracts scientists from many different fields using high-energy heavy ions delivered by large accelerator facilities and characterized by strong and short electronic excitations.

XTE J1701-407 INTEGRAL and Swift observations

DEFF Research Database (Denmark)

Soldi, S.; Beckmann, V.; Eckert, D.

2008-01-01

:27 with an on-source time of 1.7 ksec. The combined spectrum of Swift/XRT and IBIS/ISGRI (33 ksec) can be represented by an absorbed power law with intrinsic NH = 2.2e22 1/cm^2 and photon index 2.1 ± 0.1. The model flux in the 2-50 keV band is 3e-10 erg/cm^2/sec. Assuming a maximum distance of 6 kpc (Linares et...

Learning from input and memory evolution: points of vulnerability on a pathway to mastery in word learning.

Science.gov (United States)

Storkel, Holly L

2015-02-01

Word learning consists of at least two neurocognitive processes: learning from input during training and memory evolution during gaps between training sessions. Fine-grained analysis of word learning by normal adults provides evidence that learning from input is swift and stable, whereas memory evolution is a point of potential vulnerability on the pathway to mastery. Moreover, success during learning from input is linked to positive outcomes from memory evolution. These two neurocognitive processes can be overlaid on to components of clinical treatment with within-session variables (i.e. dose form and dose) potentially linked to learning from input and between-session variables (i.e. dose frequency) linked to memory evolution. Collecting data at the beginning and end of a treatment session can be used to identify the point of vulnerability in word learning for a given client and the appropriate treatment component can then be adjusted to improve the client's word learning. Two clinical cases are provided to illustrate this approach.

Defects induced by swift heavy ions in the 18R martensite of Cu-Zn-Al alloy

International Nuclear Information System (INIS)

Zelaya, Eugenia; Tolley, Alfredo; Condo, Adriana; Lovey, Francisco; Schumacher, G

2003-01-01

The swift heavy ion incidence over the surface of a given material produces a strong energy deposition in a nanometric scale.Swift heavy ions, of the order of one thousand of MeV, deposit their energy as electronic excitations.This highly localized deposition can induce metastable transformations within the material. For example, in martensitic NiTi alloys irradiated with swift heavy ions, it has been observed changes on the martensitic transformation temperature and amorphous areas induced by the irradiation.In this work, the effects produced by swift heavy ions on the martensitic 18R structure of Cu-Zn-Al alloy (Cu - 12.17 Zn - 17.92 Al, in %at) were analyzed.Crystalline samples were irradiated in a direction close to the [2 1 0] of 18R with Xe + 230 MeV, Au + of 350 MeV and Kr + of 200 MeV ion beams.Defects of the order of nanometers induced by the irradiation were observed by transmission electron microscopy (TEM) and high resolution electron microscopy (HREM).It was also observed, that the average size of the irradiation defects induced by Au + ion is larger than those induced by Xe + and Kr + ions.In this case, no relationship between the observed defects and the energy deposition was found in the 23 keV/nn to 48 keV/nn range

Impact of time and space evolution of ion tracks in nonvolatile memory cells approaching nanoscale

International Nuclear Information System (INIS)

Cellere, G.; Paccagnella, A.; Murat, M.; Barak, J.; Akkerman, A.; Harboe-Sorensen, R.; Virtanen, A.; Visconti, A.; Bonanomi, M.

2010-01-01

Swift heavy ions impacting on matter lose energy through the creation of dense tracks of charges. The study of the space and time evolution of energy exchange allows understanding the single event effects behavior in advanced microelectronic devices. In particular, the shrinking of minimum feature size of most advanced memory devices makes them very interesting test vehicles to study these effects since the device and the track dimensions are comparable; hence, measured effects are directly correlated with the time and space evolution of the energy release. In this work we are studying the time and space evolution of ion tracks by using advanced non volatile memories and Monte Carlo simulations. Experimental results are very well explained by the theoretical calculations.

Prompt Emission Observations of Swift BAT Bursts

Science.gov (United States)

Barthelmy, Scott

2009-01-01

We review the prompt emission properties of Swift BAT gamma-ray bursts (GRBs). We present the global properties of BAT GRBs based on their spectral and temporal characteristics. The BAT T90 and T50 durations peak at 80 and 20 s, respectively. The peak energy (Epeak) of about 60% of BAT GRBs is very likely to be less than 1.00 keV. We also present the BAT characteristics of GRBs with soft spectra, so called Xray flashes (XRFs). We will compare the BAT GRBs and XRFs parameter distribution to the other missions.

VERITAS OBSERVATIONS OF GAMMA-RAY BURSTS DETECTED BY SWIFT

International Nuclear Information System (INIS)

Acciari, V. A.; Benbow, W.; Aliu, E.; Errando, M.; Arlen, T.; Aune, T.; Beilicke, M.; Buckley, J. H.; Bugaev, V.; Bradbury, S. M.; Byrum, K.; Cannon, A.; Collins-Hughes, E.; Cesarini, A.; Connolly, M. P.; Christiansen, J. L.; Ciupik, L.; Cui, W.; Duke, C.; Falcone, A.

2011-01-01

We present the results of 16 Swift-triggered Gamma-ray burst (GRB) follow-up observations taken with the Very Energetic Radiation Imaging Telescope Array System (VERITAS) telescope array from 2007 January to 2009 June. The median energy threshold and response time of these observations were 260 GeV and 320 s, respectively. Observations had an average duration of 90 minutes. Each burst is analyzed independently in two modes: over the whole duration of the observations and again over a shorter timescale determined by the maximum VERITAS sensitivity to a burst with a t –1.5 time profile. This temporal model is characteristic of GRB afterglows with high-energy, long-lived emission that have been detected by the Large Area Telescope on board the Fermi satellite. No significant very high energy (VHE) gamma-ray emission was detected and upper limits above the VERITAS threshold energy are calculated. The VERITAS upper limits are corrected for gamma-ray extinction by the extragalactic background light and interpreted in the context of the keV emission detected by Swift. For some bursts the VHE emission must have less power than the keV emission, placing constraints on inverse Compton models of VHE emission.

Swift Burst Alert Telescope Data Products and Analysis Software

International Nuclear Information System (INIS)

Krimm, Hans A.; Barbier, Louis M.; Barthelmy, Scott D.; Cummings, Jay R.; Gehrels, Neil; Parsons, Ann M.; Tueller, Jack; Fenimore, Edward E.; Palmer, David M.; Hullinger, Derek D.; Markwardt, Craig B.

2004-01-01

The Burst Alert Telescope (BAT) on the Swift gamma-ray burst mission serves as the GRB trigger for Swift as well as a sensitive imaging telescope for the energy range of 15-150 keV. All BAT data products will be available to the astronomical community along with a complete set of analysis tools. Gamma-ray burst data products include rapid discovery messages delivered immediately via the GRB Coordinates Network, and event-by-event data from which light curves and spectra of the burst are generated. During nominal operations, the instrument provides accumulated survey histograms with 5-minute time sampling and appropriate energy resolution. These survey accumulations are analyzed in a pipeline to detect new sources and derive light curves of known sources. The 5-minute surveys will also be combined to produce the BAT all sky hard X-ray survey. In addition, the instrument accumulates high time resolution light curves of the brightest BAT sources in multiple energy bands, which are merged into a source light curve database on the ground. The BAT science data products and analysis tools will be described in this paper

Semantic Wavelet-Induced Frequency-Tagging (SWIFT Periodically Activates Category Selective Areas While Steadily Activating Early Visual Areas.

Directory of Open Access Journals (Sweden)

Roger Koenig-Robert

Full Text Available Primate visual systems process natural images in a hierarchical manner: at the early stage, neurons are tuned to local image features, while neurons in high-level areas are tuned to abstract object categories. Standard models of visual processing assume that the transition of tuning from image features to object categories emerges gradually along the visual hierarchy. Direct tests of such models remain difficult due to confounding alteration in low-level image properties when contrasting distinct object categories. When such contrast is performed in a classic functional localizer method, the desired activation in high-level visual areas is typically accompanied with activation in early visual areas. Here we used a novel image-modulation method called SWIFT (semantic wavelet-induced frequency-tagging, a variant of frequency-tagging techniques. Natural images modulated by SWIFT reveal object semantics periodically while keeping low-level properties constant. Using functional magnetic resonance imaging (fMRI, we indeed found that faces and scenes modulated with SWIFT periodically activated the prototypical category-selective areas while they elicited sustained and constant responses in early visual areas. SWIFT and the localizer were selective and specific to a similar extent in activating category-selective areas. Only SWIFT progressively activated the visual pathway from low- to high-level areas, consistent with predictions from standard hierarchical models. We confirmed these results with criterion-free methods, generalizing the validity of our approach and show that it is possible to dissociate neural activation in early and category-selective areas. Our results provide direct evidence for the hierarchical nature of the representation of visual objects along the visual stream and open up future applications of frequency-tagging methods in fMRI.

Implications from the Upper Limit of Radio Afterglow Emission of FRB 131104/Swift J0644.5-5111

Science.gov (United States)

Gao, He; Zhang, Bing

2017-02-01

A γ-ray transient, Swift J0644.5-5111, has been claimed to be associated with FRB 131104. However, a long-term radio imaging follow-up observation only placed an upper limit on the radio afterglow flux of Swift J0644.5-5111. Applying the external shock model, we perform a detailed constraint on the afterglow parameters for the FRB 131104/Swift J0644.5-5111 system. We find that for the commonly used microphysics shock parameters (e.g., {ɛ }e=0.1, {ɛ }B=0.01, and p = 2.3), if the fast radio burst (FRB) is indeed cosmological as inferred from its measured dispersion measure (DM), the ambient medium number density should be ≤slant {10}-3 {{cm}}-3, which is the typical value for a compact binary merger environment but disfavors a massive star origin. Assuming a typical ISM density, one would require that the redshift of the FRB be much smaller than the value inferred from DM (z\\ll 0.1), implying a non-cosmological origin of DM. The constraints are much looser if one adopts smaller {ɛ }B and {ɛ }e values, as observed in some gamma-ray burst afterglows. The FRB 131104/Swift J0644.5-5111 association remains plausible. We critically discuss possible progenitor models for the system.

Swift heavy ions induced irradiation effects in monolayer graphene and highly oriented pyrolytic graphite

International Nuclear Information System (INIS)

Zeng, J.; Yao, H.J.; Zhang, S.X.; Zhai, P.F.; Duan, J.L.; Sun, Y.M.; Li, G.P.; Liu, J.

2014-01-01

Monolayer graphene and highly oriented pyrolytic graphite (HOPG) were irradiated by swift heavy ions ( 209 Bi and 112 Sn) with the fluence between 10 11 and 10 14 ions/cm 2 . Both pristine and irradiated samples were investigated by Raman spectroscopy. It was found that D and D′ peaks appear after irradiation, which indicated the ion irradiation introduced damage both in the graphene and graphite lattice. Due to the special single atomic layer structure of graphene, the irradiation fluence threshold Φ th of the D band of graphene is significantly lower ( 11 ions/cm 2 ) than that (2.5 × 10 12 ions/cm 2 ) of HOPG. The larger defect density in graphene than in HOPG indicates that the monolayer graphene is much easier to be damaged than bulk graphite by swift heavy ions. Moreover, different defect types in graphene and HOPG were detected by the different values of I D /I D′ . For the irradiation with the same electronic energy loss, the velocity effect was found in HOPG. However, in this experiment, the velocity effect was not observed in graphene samples irradiated by swift heavy ions

Single ion induced surface nanostructures: a comparison between slow highly charged and swift heavy ions.

Science.gov (United States)

Aumayr, Friedrich; Facsko, Stefan; El-Said, Ayman S; Trautmann, Christina; Schleberger, Marika

2011-10-05

This topical review focuses on recent advances in the understanding of the formation of surface nanostructures, an intriguing phenomenon in ion-surface interaction due to the impact of individual ions. In many solid targets, swift heavy ions produce narrow cylindrical tracks accompanied by the formation of a surface nanostructure. More recently, a similar nanometric surface effect has been revealed for the impact of individual, very slow but highly charged ions. While swift ions transfer their large kinetic energy to the target via ionization and electronic excitation processes (electronic stopping), slow highly charged ions produce surface structures due to potential energy deposited at the top surface layers. Despite the differences in primary excitation, the similarity between the nanostructures is striking and strongly points to a common mechanism related to the energy transfer from the electronic to the lattice system of the target. A comparison of surface structures induced by swift heavy ions and slow highly charged ions provides a valuable insight to better understand the formation mechanisms. © 2011 IOP Publishing Ltd

Use of analogues to build technologists' confidence: NAnet

International Nuclear Information System (INIS)

Noseck, Ulrich

2008-01-01

The relevance of analogues to radioactive waste management stems from the long timescales that have to be considered. Periods up to a million or more years into the future need to be considered and these are beyond experimental investigation and human experience. Within the last years the term 'Natural Analogue' has got a much wider meaning and includes man-made analogues as well. The role of natural analogues in the safety case depends amongst others on the time scale to be covered. Therefore, it is useful to classify them by the time period addressed in the study. Here it is referred to: industrial analogues which started earliest 150 years ago, archaeological analogues, which cover time frames between the past 10 000 and 150 years, and geological analogues, which usually cover time frames of more than 10 000 years and in most cases more than million years. The current interest in analogues in different countries is reflected by several recent review projects with emphasis on the application of natural analogue study results in performance assessment. The most recent international review was performed within the 5. EURATOM Framework of the EC by the NAnet project, a network on the review of natural analogue studies with emphasis on the application of analogues in long-term safety assessment and communication. The overall aim of the NAnet project was to review the past and present use and understanding of natural analogues, and to make recommendations for their future use. The project covered 'traditional' natural analogue studies, such as large-scale investigations of radionuclide transport around uranium ore bodies, and process or mechanistic analogue studies such as those examining natural glass and bentonite clay stability. To complete the picture, a restricted range of other studies of natural systems which employ a similar philosophy to analogues was also included in the scope. These included studies which have examined radionuclide transport and retardation

Supergiant fast X-ray transients with Swift: Spectroscopic and temporal properties

Science.gov (United States)

Romano, P.; Mangano, V.; Ducci, L.; Esposito, P.; Farinelli, R.; Ceccobello, C.; Vercellone, S.; Burrows, D. N.; Kennea, J. A.; Krimm, H. A.; Gehrels, N.

2012-12-01

Supergiant fast X-ray transients (SFXTs) are a class of high-mass X-ray binaries with possible counterparts in the high energy gamma rays. The Swift SFXT Project1 has conducted a systematic investigation of the properties of SFTXs on timescales ranging from minutes to years and in several intensity states (from bright flares, to intermediate intensity states, and down to almost quiescence). We also performed broad-band spectroscopy of outbursts, and intensity-selected spectroscopy outside of outbursts. We demonstrated that while the brightest phase of the outburst only lasts a few hours, further activity is observed at lower fluxes for a remarkably longer time, up to weeks. Furthermore, we assessed the fraction of the time these sources spend in each phase, and their duty cycle of inactivity. We present the most recent results from our investigation. The spectroscopic and, most importantly, timing properties of SFXTs we have uncovered with Swift will serve as a guide in search for the high energy emission from these enigmatic objects.

Swift/BAT confirms the giant outburst of H 1417-624

Science.gov (United States)

Krimm, H. A.; Barthelmy, S. D.; Cummings, J. R.; Lien, A. Y.; Markwardt, C. B.; Palmer, D. M.; Sakamoto, T.; Stamatikos, M.; Ukwatta, T. N.

2018-04-01

The Swift/BAT transient monitor confirms the current outburst from the Be/X-ray binary pulsar, H 1417-624 ( = 2S 1417-624) (Nakajima et al., ATel #11479). In the BAT 15-50 keV energy band, the outburst began approximately on 20 March 2018 (MJD 57467) and the count rate has been steadily rising since that time.

VizieR Online Data Catalog: Short GRBs with Fermi GBM and Swift BAT (Burns+, 2016)

Science.gov (United States)

Burns, E.; Connaughton, V.; Zhang, B.-B.; Lien, A.; Briggs, M. S.; Goldstein, A.; Pelassa, V.; Troja, E.

2018-01-01

Compact binary system mergers are expected to generate gravitational radiation detectable by ground-based interferometers. A subset of these, the merger of a neutron star with another neutron star or a black hole, are also the most popular model for the production of short gamma-ray bursts (GRBs). The Swift Burst Alert Telescope (BAT) and the Fermi Gamma-ray Burst Monitor (GBM) trigger on short GRBs (SGRBs) at rates that reflect their relative sky exposures, with the BAT detecting 10 per year compared to about 45 for GBM. We examine the SGRB populations detected by Swift BAT and Fermi GBM. (4 data files).

Natural and archaeological analogues: a review

International Nuclear Information System (INIS)

Brookins, D.G.

1987-01-01

In this chapter natural analogues in the geomedia for various aspects of radioactive waste disposal are discussed. Particular reference is made to the Okla Natural Reactor in Gabon. Igneous contact zones are discussed and natural analogues of waste-form materials. The importance of archaeological remains and anthropogenic materials left by man, in assessing weathering conditions and serving as radioactive waste analogues, is also emphasised. (UK)

Swift observations of GS 1826-238

Science.gov (United States)

Ji, L.; Santangelo, A.; Zhang, S.; Ducci, L.; Suleimanov, V.

2018-02-01

GS 1826-238 is a well-studied low-mass X-ray binary neutron star. This source was in a persistent hard state since its discovery in 1988 and until 2014 June. After that, the source exhibited several softer periods of enhanced intensity in the energy range 2-20 keV. We studied the long-term light curves of MAXI (Monitor of All Sky X-ray Image) and Swift/BAT, and found clearly two branches in the MAXI-BAT and hardness-intensity diagrams, which correspond to the persistent state and softer periods, respectively. We analysed 21 Swift/XRT observations, of which four were located in the persistent state while the others were in softer periods or in a state between them. The XRT spectra could be generally fitted by using an absorbed Comptonization model with no other components required. We found a peculiar relationship between the luminosity and the hardness in the energy range of 0.6-10 keV: when the luminosity is larger (smaller) than 4 per cent-6 per cent Ledd, the hardness is anti-correlated (correlated) with luminosity. We also estimated the variability for each observation by using the fractional rms in the 0.1-10 Hz range. We found that the observations in the persistent state had a large fractional rms of ˜25 per cent, similar to other low-mass X-ray binaries. However, the variability is mainly found in the range of 5 per cent-20 per cent during softer periods. We suggest that GS 1826-238 did not evolve into the soft state of atoll sources, and all the observed XRT observations during the softer periods resemble a peculiar intermediate state of atoll sources.

Indicators of suboptimal performance embedded in the Wechsler Memory Scale-Fourth Edition (WMS-IV)

OpenAIRE

Bouman, Zita; Hendriks, Marc PH; Schmand, Ben A; Kessels, Roy PC; Aldenkamp, Albert

2016-01-01

Introduction. Recognition and visual working memory tasks from the Wechsler Memory Scale-Fourth Edition (WMS-IV) have previously been documented as useful indicators for suboptimal performance. The present study examined the clinical utility of the Dutch version of the WMS-IV (WMS-IV-NL) for the identification of suboptimal performance using an analogue study design. Method. The patient group consisted of 59 mixed-etiology patients; the experimental malingerers were 50 healthy individuals...

Indicators of suboptimal performance embedded in the Wechsler Memory Scale-Fourth Edition (WMS-IV)

OpenAIRE

Bouman, Zita; Hendriks, Marc P.H.; Schmand, Ben A.; Kessels, Roy P.C.; Aldenkamp, Albert P.

2016-01-01

Introduction. Recognition and visual working memory tasks from the Wechsler Memory Scale-Fourth Edition (WMS-IV) have previously been documented as useful indicators for suboptimal performance. The present study examined the clinical utility of the Dutch version of the WMS-IV (WMS-IV-NL) for the identification of suboptimal performance using an analogue study design.Method. The patient group consisted of 59 mixed-etiology patients; the experimental malingerers were 50 healthy individuals who ...

Swift observations of SDSS J141118.31+481257.6 during superoutburst

Science.gov (United States)

Rivera Sandoval, L. E.; Maccarone, T.

2018-06-01

We report on follow-up Swift observations of the AM CVn-type binary SDSS J141118.31+481257.6 (ATEL #11668, #11672). Based on ground based photometry, the re-brightening previous to the current superoutburst was reported on 2018-June-1 (https://www.aavso.org/aavso-alert-notice-636).

Understanding care farming as a swiftly developing sector in the Netherlands

NARCIS (Netherlands)

Hassink, J.

2017-01-01

Care farming or social farming is a swiftly developing sector across Europe. Care farms combine agricultural production with health and social services. The Netherlands is one of the leading countries in care farming. The aim of this study was to better understand how the new sector of care farming

THE COLLIMATION AND ENERGETICS OF THE BRIGHTEST SWIFT GAMMA-RAY BURSTS

International Nuclear Information System (INIS)

Cenko, S. B.; Butler, N. R.; Bloom, J. S.; Frail, D. A.; Harrison, F. A.; Kulkarni, S. R.; Kasliwal, M. M.; Ofek, E. O.; Rau, A.; Nakar, E.; Chandra, P. C.; Fox, D. B.; Gal-Yam, A.; Kelemen, J.; Moon, D.-S.; Price, P. A.; Soderberg, A. M.; Teplitz, H. I.; Werner, M. W.; Bock, D. C.-J.

2010-01-01

Long-duration gamma-ray bursts (GRBs) are widely believed to be highly collimated explosions (bipolar conical outflows with half-opening angle θ∼ 1 0 -10 0 ). As a result of this beaming factor, the true energy release from a GRB is usually several orders of magnitude smaller than the observed isotropic value. Measuring this opening angle, typically inferred from an achromatic steepening in the afterglow light curve (a 'jet' break), has proven exceedingly difficult in the Swift era. Here, we undertake a study of five of the brightest (in terms of the isotropic prompt γ-ray energy release, E γ,iso ) GRBs in the Swift era to search for jet breaks and hence constrain the collimation-corrected energy release. We present multi-wavelength (radio through X-ray) observations of GRBs 050820A, 060418, and 080319B, and construct afterglow models to extract the opening angle and beaming-corrected energy release for all three events. Together with results from previous analyses of GRBs 050904 and 070125, we find evidence for an achromatic jet break in all five events, strongly supporting the canonical picture of GRBs as collimated explosions. The most natural explanation for the lack of observed jet breaks from most Swift GRBs is therefore selection effects. However, the opening angles for the events in our sample are larger than would be expected if all GRBs had a canonical energy release of ∼10 51 erg. The total energy release we measure for the 'hyper-energetic' (E tot ∼> 10 52 erg) events in our sample is large enough to start challenging models with a magnetar as the compact central remnant.

Study of the point defect creation and of the excitonic luminescence in alkali halides irradiated by swift heavy ions

International Nuclear Information System (INIS)

Protin, L.

1994-01-01

The aim of this experimental thesis is to study the excitonic mechanisms and of the defect creation, in NaCl and KBr, under dense electronic excitations induced by swift heavy ion irradiations. In the first part, we present the main features of the interaction of swift heavy ions with solid targets, and after we review the well known radiolytic processes of the defect creation during X-ray irradiation. In the second chapter, we describe our experimental set-up. In the chapter III, we present our results of the in-situ optical absorption measurements. This results show that defect creation is less sensitive to the temperature than during a classical irradiation. Besides, we observe new mechanisms concerning the defect aggregation. In the chapter IV, we present the results of excitonic luminescence induced by swift by swift heavy ions. We observe that the luminescence yields only change with the highest electronic stopping power. In the chapter V, we perform thermal spike and luminescence yields calculations and we compare the numerical results to the experiments presented in the chapter IV. (author). 121 refs., 65 figs., 30 tabs

Solid Waste Integrated Forecast Technical (SWIFT) Report FY 2001 to FY 2046 Volume 2

International Nuclear Information System (INIS)

BARCOT, R.A.

2001-01-01

The SWIFT Report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. This report is a mid-year update to the SWIFT 2001.0 report that was published in August 2000. The data contained in this report is the official data for solid waste forecasting until the SWIFT 2002.0 data is published in August 2001. This particular volume provides the following data reports: Annual volume data by waste generator; Summary volume data by location and DOE Office; Annual container type data by volume and count; and Annual physical waste form and waste specification record volume. This report also includes several minor changes from previous versions in an effort to increase the usability of the data and align with current Hanford Site organization changes. The changes include: Minor changes to waste generator names to make them more recognizable; Grouping of the waste generators into DOE Office and location (e.g, Office of River Protection, Fluor Hanford, Bechtel, etc); Addition of WSRd and Container Count sections; and Elimination of the ''functional group'' organization of the data (e.g., Facilities Transition, Spent Nuclear Fuel, etc)

Activation of a remote (1-year old) emotional memory interferes with the retrieval of a newly formed hippocampus-dependent memory in rats.

Science.gov (United States)

Zoladz, Phillip R; Woodson, James C; Haynes, Vernon F; Diamond, David M

2010-01-01

The persistent intrusion of remote traumatic memories in people with post-traumatic stress disorder (PTSD) may contribute to the impairment of their ongoing hippocampal and prefrontal cortical functioning. In the current work, we have developed a rodent analogue of the intrusive memory phenomenon. We studied the influence of the activation of a remote traumatic memory in rats on their ability to retrieve a newly formed hippocampus-dependent memory. Adult male Sprague-Dawley rats were given inhibitory avoidance (IA) training, and then 24 h or 1, 6 or 12 months later, the same rats were trained to learn, and then remember across a 30-min delay period, the location of a hidden escape platform in the radial-arm water maze (RAWM). When IA-trained rats spent the 30-min delay period in the IA apparatus, they exhibited intact remote (1-year old) memory of the shock experience. More importantly, activation of the rats' memory of the shock experience profoundly impaired their ability to retrieve the newly formed spatial memory of the hidden platform location in the RAWM. Our finding that reactivation of a remote emotional memory exerted an intrusive effect on new spatial memory processing in rats provides a novel approach toward understanding how intrusive memories of traumatic experiences interfere with ongoing cognitive processing in people with PTSD.

Further NICER observations of the accreting millisecond pulsar Swift J1756.9-2508

Science.gov (United States)

Bult, P. M.; Gendreau, K. C.; Ray, P. S.; Altamirano, D.; Arzoumanian, Z.; Strohmayer, T. E.; Homan, J.; Chakrabarty, D.

2018-04-01

The accreting millisecond X-ray pulsar Swift J1756.9-2508 has been in outburst since 2018 April 1 (ATel #11497, #11502, #11505, #11523, #11566) and has been subject to regular monitoring with NICER (ATel #11502).

Analogue to Digital and Digital to Analogue Converters (ADCs and DACs): A Review Update

CERN Document Server

Pickering, J.

2015-06-15

This is a review paper updated from that presented for CAS 2004. Essentially, since then, commercial components have continued to extend their performance boundaries but the basic building blocks and the techniques for choosing the best device and implementing it in a design have not changed. Analogue to digital and digital to analogue converters are crucial components in the continued drive to replace analogue circuitry with more controllable and less costly digital processing. This paper discusses the technologies available to perform in the likely measurement and control applications that arise within accelerators. It covers much of the terminology and 'specmanship' together with an application-oriented analysis of the realisable performance of the various types. Finally, some hints and warnings on system integration problems are given.

Data input guide for SWIFT II. The Sandia waste-isolation flow and transport model for fractured media, Release 4.84

International Nuclear Information System (INIS)

Reeves, M.; Ward, D.S.; Johns, N.D.; Cranwell, R.M.

1986-04-01

This report is one of three which describes the SWIFT II computer code. The code simulates flow and transport processes in geologic media which may be fractured. SWIFT II was developed for use in the analysis of deep geologic facilities for nuclear-waste disposal. This user's manual should permit the analyst to use the code effectively by facilitating the preparation of input data. A second companion document discusses the theory and implementation of the models employed by the SWIFT II code. A third document provides illustrative problems for instructional purposes. This report contains detailed descriptions of the input data along with an appendix of the input diagnostics. The use of auxiliary files, unit conversions, and program variable descriptors also are included in this document

Opto-chemical response of Makrofol-KG to swift heavy ion irradiation

Indian Academy of Sciences (India)

In the present study, the effects of swift heavy ion beam irradiation on the structural, chemical and optical properties of Makrofol solid-state nuclear track detector (SSNTD) were investigated. Makrofol-KG films of 40 m thickness were irradiated with oxygen beam (8+) with fluences ranging between 1010 ion/cm2 and 1012 ...

INTEGRAL observation of the Galactic transient Swift J174510.8-262411

DEFF Research Database (Denmark)

Vovk, I.; Ferrigno, C.; Bozzo, E.

2012-01-01

with time. On the base of the rapid flux increase, the high value of the energy cut-off and the absence of thermonuclear bursts, we argue that Swift J174510.8-262411 might be a new black-hole transient. Further observations at all wavelengths are encouraged to unveil the nature of this source. We thank...

The Psychological Concepts in Taylor Swift's "Blank Space"

OpenAIRE

Anindhita, Novia Putri

2016-01-01

“Blank Space” is a song that is sung by a singer, Taylor Swift. The lyrics tell about the lonely woman who dates a lot but always fails to manage her relationship. However, it does not make her worry to start a new relationship. The purpose of this study is to analyze the elements of the poetry in the lyrics and to show the readers the psychological contents as portrayed in the music video. The study uses intrinsic and extrinsic theories to analyze the data and library research to compile the...

Determination of the distance to SWIFT J0243.6+6124

Science.gov (United States)

Bikmaev, I.; Shimansky, V.; Irtuganov, E.; Glushkov, M.; Sakhibullin, N.; Khamitov, I.; Burenin, R.; Lutovinov, A.; Zaznobin, I.; Pavlinsky, M.; Sunyaev, R.; Dodonov, S.; Afanasiev, V.; Kotov, S.; Doroshenko, V.; Tsygankov, S.

2017-11-01

We have performed an optical photometry and spectroscopy of the Be counterpart of a newly discovered transient X-Ray pulsar SWIFT J0243.6+6124 (Kennea et al, 2017, ATel #10809) using facilities of the 1.5-meter Russian-Turkish telescope (RTT-150, TUBITAK National Observatory, Antalya, Turkey) and the 6-meter Russian telescope (BTA, Special Astrophysical Observatory of the Russian Academy of Sciences).

Swift pointing and gravitational-wave bursts from gamma-ray burst events

International Nuclear Information System (INIS)

Sutton, Patrick J; Finn, Lee Samuel; Krishnan, Badri

2003-01-01

The currently accepted model for gamma-ray burst phenomena involves the violent formation of a rapidly rotating solar-mass black hole. Gravitational waves should be associated with the black-hole formation, and their detection would permit this model to be tested. Even upper limits on the gravitational-wave strength associated with gamma-ray bursts could constrain the gamma-ray burst model. This requires joint observations of gamma-ray burst events with gravitational and gamma-ray detectors. Here we examine how the quality of an upper limit on the gravitational-wave strength associated with gamma-ray bursts depends on the relative orientation of the gamma-ray-burst and gravitational-wave detectors, and apply our results to the particular case of the Swift Burst-Alert Telescope (BAT) and the LIGO gravitational-wave detectors. A result of this investigation is a science-based 'figure of merit' that can be used, together with other mission constraints, to optimize the pointing of the Swift telescope for the detection of gravitational waves associated with gamma-ray bursts

Quantum analogue computing.

Science.gov (United States)

Kendon, Vivien M; Nemoto, Kae; Munro, William J

2010-08-13

We briefly review what a quantum computer is, what it promises to do for us and why it is so hard to build one. Among the first applications anticipated to bear fruit is the quantum simulation of quantum systems. While most quantum computation is an extension of classical digital computation, quantum simulation differs fundamentally in how the data are encoded in the quantum computer. To perform a quantum simulation, the Hilbert space of the system to be simulated is mapped directly onto the Hilbert space of the (logical) qubits in the quantum computer. This type of direct correspondence is how data are encoded in a classical analogue computer. There is no binary encoding, and increasing precision becomes exponentially costly: an extra bit of precision doubles the size of the computer. This has important consequences for both the precision and error-correction requirements of quantum simulation, and significant open questions remain about its practicality. It also means that the quantum version of analogue computers, continuous-variable quantum computers, becomes an equally efficient architecture for quantum simulation. Lessons from past use of classical analogue computers can help us to build better quantum simulators in future.

Implications from the upper limit of radio afterglow emission of FRB 131104/Swift J0644.5-5111

OpenAIRE

Gao, He; Zhang, Bing

2016-01-01

A $\\gamma$-ray transient, Swift J0644.5-5111, has been claimed to be associated with FRB 131104. The $\\gamma$-ray energy output is estimated as $E_\\gamma \\approx 5\\times 10^{51}$\\,erg at the nominal $z\\approx 0.55$ redshift implied by the dispersion measure of FRB 131104. However, a long-term radio imaging follow-up observations only place an upper limit on the radio afterglow flux of Swift J0644.5-5111. Applying the external shock model, we make a detailed constraint on the afterglow paramet...

Intrinsic Ferroelasticity and/or Multiferroicity in Two-Dimensional Phosphorene and Phosphorene Analogues.

Science.gov (United States)

Wu, Menghao; Zeng, Xiao Cheng

2016-05-11

Phosphorene and phosphorene analogues such as SnS and SnSe monolayers are promising nanoelectronic materials with desired bandgap, high carrier mobility, and anisotropic structures. Here, we show first-principles calculation evidence that these monolayers are potentially the long-sought two-dimensional (2D) materials that can combine electronic transistor characteristic with nonvolatile memory readable/writeable capability at ambient condition. Specifically, phosphorene is predicted to be a 2D intrinsic ferroelastic material with ultrahigh reversible strain, whereas SnS, SnSe, GeS, and GeSe monolayers are multiferroic with coupled ferroelectricity and ferroelasticity. Moreover, their low-switching barriers render room-temperature nonvolatile memory accessible, and their notable structural anisotropy enables ferroelastic or ferroelectric switching readily readable via electrical, thermal, optical, mechanical, or even spintronic detection upon the swapping of the zigzag and armchair direction. In addition, it is predicted that the GeS and GeSe monolayers as well as bulk SnS and SnSe can maintain their ferroelasticity and ferroelectricity (anti-ferroelectricity) beyond the room temperature, suggesting high potential for practical device application.

The Chandra Dust-scattering Halo of Galactic Center Transient Swift J174540.7–290015

Energy Technology Data Exchange (ETDEWEB)

Corrales, L. R. [Einstein Fellow, University of Wisconsin-Madison, 475 North Charter Street, Madison, WI, 53706 (United States); Mon, B.; Haggard, D. [McGill Space Institute, McGill University, 3550 University Street, Montreal, QC, H3A 2A7 (Canada); Baganoff, F. K. [MIT Kavli Institute for Astrophysics and Space Research, 77 Massachusetts Avenue, Cambridge, MA, 02139 (United States); Garmire, G. [Huntingdon Institute for X-ray Astronomy, 10677 Franks Road Huntingdon, PA, 16652 (United States); Degenaar, N. [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 OHA (United Kingdom); Reynolds, M. [University of Michigan, 1085 S. University, 311 West Hall, Ann Arbor, MI 48109 (United States)

2017-04-20

We report the detection of a dust-scattering halo around a recently discovered X-ray transient, Swift J174540.7–290015, which in early 2016 February underwent one of the brightest outbursts ( F {sub X} ≈ 5 × 10{sup −10} erg cm{sup −2} s{sup −1}) observed from a compact object in the Galactic Center field. We analyze four Chandra images that were taken as follow-up observations to Swift discoveries of new Galactic Center transients. After adjusting our spectral extraction for the effects of detector pile-up, we construct a point-spread function for each observation and compare it to the GC field before the outburst. We find residual surface brightness around Swift J174540.7–290015, which has a shape and temporal evolution consistent with the behavior expected from X-rays scattered by foreground dust. We examine the spectral properties of the source, which shows evidence that the object transitioned from a soft to hard spectral state as it faded below L {sub X} ∼ 10{sup 36} erg s{sup −1}. This behavior is consistent with the hypothesis that the object is a low-mass X-ray binary in the Galactic Center.

INTEGRAL observation of SWIFT J1756.9-2508 in outburst

Science.gov (United States)

Mazzola, S.; Bozzo, E.; Kuulkers, E.; Ferrigno, C.; Savchenko, V.; Ducci, L.

2018-04-01

Following the discovery of a new outburst from the accreting millisecond X-ray pulsar SWIFT J1756.9-2508 (ATel #11497, #11502, #11505), a dedicated target of opportunity observation with INTEGRAL was carried out from 2018 April 1 at 08:30 to 23:15 (UTC; total exposure time 85 ks). The source was detected in the 20-40 keV IBIS/ISGRI mosaic at a significance level of 20 sigma.

BALANOL ANALOGUES

DEFF Research Database (Denmark)

1997-01-01

The present invention relates to a solid phase methodology for the preparation of a combinatorial library of structural analogues of the natural product balanol (ophiocordin, azepinostatin), which is a protein kinase C (PKC) and protein kinase A (PKA) inhibitor. The method comprises solid...

Fossil evidence of wing shape in a stem relative of swifts and hummingbirds (Aves, Pan-Apodiformes).

Science.gov (United States)

Ksepka, Daniel T; Clarke, Julia A; Nesbitt, Sterling J; Kulp, Felicia B; Grande, Lance

2013-06-22

A feathered specimen of a new species of Eocypselus from the Early Eocene Green River Formation of Wyoming provides insight into the wing morphology and ecology in an early part of the lineage leading to extant swifts and hummingbirds. Combined phylogenetic analysis of morphological and molecular data supports placement of Eocypselus outside the crown radiation of Apodiformes. The new specimen is the first described fossil of Pan-Apodiformes from the pre-Pleistocene of North America and the only reported stem taxon with informative feather preservation. Wing morphology of Eocypselus rowei sp. nov. is intermediate between the short wings of hummingbirds and the hyper-elongated wings of extant swifts, and shows neither modifications for the continuous gliding used by swifts nor modifications for the hovering flight style used by hummingbirds. Elongate hindlimb elements, particularly the pedal phalanges, also support stronger perching capabilities than are present in Apodiformes. The new species is the smallest bird yet described from the Green River Formation, and supports the hypothesis that a decrease in body size preceded flight specializations in Pan-Apodiformes. The specimen also provides the first instance of melanosome morphology preserved in association with skeletal remains from the Green River Formation.

Exponential stability of continuous-time and discrete-time bidirectional associative memory networks with delays

International Nuclear Information System (INIS)

Liang Jinling; Cao Jinde

2004-01-01

First, convergence of continuous-time Bidirectional Associative Memory (BAM) neural networks are studied. By using Lyapunov functionals and some analysis technique, the delay-independent sufficient conditions are obtained for the networks to converge exponentially toward the equilibrium associated with the constant input sources. Second, discrete-time analogues of the continuous-time BAM networks are formulated and studied. It is shown that the convergence characteristics of the continuous-time systems are preserved by the discrete-time analogues without any restriction imposed on the uniform discretionary step size. An illustrative example is given to demonstrate the effectiveness of the obtained results

Room-temperature antiferromagnetic memory resistor.

Science.gov (United States)

Marti, X; Fina, I; Frontera, C; Liu, Jian; Wadley, P; He, Q; Paull, R J; Clarkson, J D; Kudrnovský, J; Turek, I; Kuneš, J; Yi, D; Chu, J-H; Nelson, C T; You, L; Arenholz, E; Salahuddin, S; Fontcuberta, J; Jungwirth, T; Ramesh, R

2014-04-01

The bistability of ordered spin states in ferromagnets provides the basis for magnetic memory functionality. The latest generation of magnetic random access memories rely on an efficient approach in which magnetic fields are replaced by electrical means for writing and reading the information in ferromagnets. This concept may eventually reduce the sensitivity of ferromagnets to magnetic field perturbations to being a weakness for data retention and the ferromagnetic stray fields to an obstacle for high-density memory integration. Here we report a room-temperature bistable antiferromagnetic (AFM) memory that produces negligible stray fields and is insensitive to strong magnetic fields. We use a resistor made of a FeRh AFM, which orders ferromagnetically roughly 100 K above room temperature, and therefore allows us to set different collective directions for the Fe moments by applied magnetic field. On cooling to room temperature, AFM order sets in with the direction of the AFM moments predetermined by the field and moment direction in the high-temperature ferromagnetic state. For electrical reading, we use an AFM analogue of the anisotropic magnetoresistance. Our microscopic theory modelling confirms that this archetypical spintronic effect, discovered more than 150 years ago in ferromagnets, is also present in AFMs. Our work demonstrates the feasibility of fabricating room-temperature spintronic memories with AFMs, which in turn expands the base of available magnetic materials for devices with properties that cannot be achieved with ferromagnets.

Cephalostatin analogues--synthesis and biological activity.

Science.gov (United States)

Flessner, Timo; Jautelat, Rolf; Scholz, Ulrich; Winterfeldt, Ekkehard

2004-01-01

Starting off in the early 90's the field of cephalostatin analogues has continually expanded over the last 10 years. First syntheses prepared symmetric analogues like 14b (119) and 26 (65), which were subsequently desymmetrized to provide analogues like beta-hydroxy ketone 31 (19). Importantly the straightforward approach provided already compounds with mu-molar potency and the same pattern of activity as cephalostatin 1 (1) (see Chapter 2.1). Chemically more demanding, two new methods for the directed synthesis of (bissteroidal) pyrazines were devised and subsequently applied to a wide variety of differently functionalized coupling partners. These new methods allowed for the synthesis of various analogues (Chapter 2.2.; and, last but not least, for the totals synthesis of several cephalostatin natural products; Chapter 1.). Functionalization and derivatization of the 12-position was performed (Chapter 2.1 and 3) and synthetic approaches to establish the D-ring double bond were successfully investigated (Chapter 3). [figure: see text] Dealing synthetically with the spiroketal moiety, novel oxidative opening procedures on monomeric delta 14, 15-steroids were devised as well as intensive studies regarding spiroketal synthesis and spiroketal rearrangements were conducted (Chapter 3.2. and 4.). Last but not least direct chemical modification of ritterazines and cephalostatins were studied, which provided a limited number of ritterazine analogues (Chapter 4.). All these synthetic activities towards analogues are summarized in Fig. 18. During this period of time the growing number of cephalostatins and ritterazines on the one hand and of analogues on the other hand provided several SAR trends, which can guide future analogue synthesis. The combined SAR findings are displayed in Fig. 19. So far it is apparent that: Additional methoxylations or hydroxylations in the steroidal A ring core structure (1-position) are slightly decreasing activity (compare cephalostatin 1 1 to

Analogue to Digital and Digital to Analogue (AD/DA) Conversion Techniques: An Overview

CERN Multimedia

CERN. Geneva

2002-01-01

The basic ideas behind modern Analogue to Digital and Digital to Analogue (AD/DA) conversion methods will be introduced: a general view of the importance of these devices will be given, along with the digital representation of time-varying, real-world analogue signals. Some CERN applications will be outlined. The variety of conversion methods, their limitations, error sources and measurement methods will form the major part of this presentation. A review of the technological progress in this field over the last 30 years will be presented, concluding with the present 'state of the art' and a quick look at what is just around the corner. This Technical Training Seminar is in the framework of the FEED-2002 Lecture Series, and it is a prerequisite to attending to any of the FEED-2002 Terms. FEED-2002 is a two-term course that will review the techniques dealing with closed loop systems, focussing on time-invariant linear systems. (free attendance, no registration required) More information on the FEED-2002 ...

5-Bromo-2'-deoxyuridine impairs long-term food aversion memory in edible snail.

Science.gov (United States)

Efimova, O I; Anokhin, K V

2012-09-01

We studied the involvement of DNA synthesis into molecular mechanisms of long-term memory. Nucleoside analogue 5-bromo-2'-deoxyuridine (BrdU) is known to incorporate into synthesizing DNA and prevent subsequent DNA replication from this region. To investigate the effect of BrdU administration on long-term memory, terrestrial gastropods edible snails Helix lucorum were trained in the food aversion paradigm. Single-session training (carrot presentation combined with application of 10% quinine solution, three carrot presentations with 10-min intervals) resulted in the formation of long-term memory that persisted for at least 45° days. BrdU administration (250 mg/kg) 30 min before training impaired long-term memory tested 24 h later. Immunohistochemical study revealed BrdU incorporation in the nuclei of identified neurons of defensive behavior.

THE THIRD SWIFT BURST ALERT TELESCOPE GAMMA-RAY BURST CATALOG

Energy Technology Data Exchange (ETDEWEB)

Lien, Amy; Baumgartner, Wayne H.; Cannizzo, John K.; Collins, Nicholas R.; Krimm, Hans A.; Troja, Eleonora [Center for Research and Exploration in Space Science and Technology (CRESST) and NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Sakamoto, Takanori [Department of Physics and Mathematics, College of Science and Engineering, Aoyama Gakuin University, 5-10-1 Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa 252-5258 (Japan); Barthelmy, Scott D.; Cummings, Jay R.; Gehrels, Neil; Markwardt, Craig B. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Chen, Kevin [Department of Physics, University of California, Berkeley, 366 LeConte Hall MC 7300, Berkeley, CA 9472 (United States); Palmer, David M.; Ukwatta, T. N. [Space and Remote Sensing (ISR-2), Los Alamos National Laboratory, Los Alamos, NM 87544 (United States); Stamatikos, Michael [Department of Physics, Department of Astronomy and Center for Cosmology and AstroParticle Physics, Ohio State University, Columbus, OH 43210 (United States)

2016-09-20

To date, the Burst Alert Telescope (BAT) onboard Swift has detected ∼1000 gamma-ray bursts (GRBs), of which ∼360 GRBs have redshift measurements, ranging from z = 0.03 to z = 9.38. We present the analyses of the BAT-detected GRBs for the past ∼11 years up through GRB 151027B. We report summaries of both the temporal and spectral analyses of the GRB characteristics using event data (i.e., data for each photon within approximately 250 s before and 950 s after the BAT trigger time), and discuss the instrumental sensitivity and selection effects of GRB detections. We also explore the GRB properties with redshift when possible. The result summaries and data products are available at http://swift.gsfc.nasa.gov/results/batgrbcat/index.html. In addition, we perform searches for GRB emissions before or after the event data using the BAT survey data. We estimate the false detection rate to be only one false detection in this sample. There are 15 ultra-long GRBs (∼2% of the BAT GRBs) in this search with confirmed emission beyond ∼1000 s of event data, and only two GRBs (GRB 100316D and GRB 101024A) with detections in the survey data prior to the starting of event data.

Disjunction and conjunction fallacies in episodic memory.

Science.gov (United States)

Nakamura, K; Brainerd, C J

2017-09-01

It has recently been found that episodic memory displays analogues of the well-known disjunction and conjunction fallacies of probability judgement. The aim of the present research was, for the first time, to study these memory fallacies together under the same conditions, and test theoretical predictions about the reasons for each. The focus was on predictions about the influence of semantic gist, target versus context recollection, and proactive versus retroactive interference. Disjunction and conjunction fallacies increased in conditions in which subjects were able to form semantic connections among list words. In addition, disjunction fallacies were increased by manipulations that minimised proactive interference, whereas conjunction fallacies were increased by manipulations that minimised retroactive interference. That pattern suggests that disjunction fallacies are more dependent on target recollection, whereas conjunction fallacies are more dependent on context recollection.

Fermi/GBM Update on the Orbital Ephemeris of Swift J0243.6+6124

Science.gov (United States)

Jenke, P.; Wilson-Hodge, C. A.; Malacaria, C.

2018-02-01

Using Fermi/GBM data between MJD 58098 and 58154 (2017 December 11 to 2018 February 5) in the 12-50 keV range, we determine a new orbital ephemeris for the newly discovered (ATEL #10809) Be X-ray binary Swift J0243.6+6124.

What SWIFT has taught us about X-ray flashes and long-duration gamma-ray bursts

CERN Document Server

De Rújula, Alvaro

2007-01-01

Recent data gathered and triggered by the SWIFT satellite have greatly improved our knowledge of long-duration gamma ray bursts (GRBs) and X-ray flashes (XRFs). This is particularly the case for the X-ray data at all times, and for UV and optical data at very early times. I show that the optical and X-ray observations are in excellent agreement with the predictions of the "cannonball" model of GRBs and XRFs. Elementary physics and just two mechanisms underlie these predictions: inverse Compton scattering and synchrotron radiation, generally dominant at early and late times, respectively. I put this result in its proper context and dedicate the paper to those who planed, built and operate SWIFT, a true flying jewel.

Swift detections of the flaring blazar GAIA 18ayp (PKS 2333-415) in X-rays and the UV

Science.gov (United States)

Grupe, Dirk; Komossa, S.; Angioni, R.; Schartel, N.

2018-04-01

We report Swift observations of the z=1.41 QSO GAIA 18ayp (PKS 2333-415) which was detected by GAIA in an optically flaring state on 2018-April-14. Swift observed GAIA 18ayp on 2018 April 23 for a total of 1.4 ks. The QSO is clearly detected in X-rays and the UV. The X-ray position found using the enhanced XRT position (Goad et al. 2007, Evans et al. 2009) is RA-2000 = 23 36 34.1, Dec-2000 = -41 15 21.4 with an uncertainty of 3.0".

International video project on natural analogues

International Nuclear Information System (INIS)

Guentensperger, Marcel

1993-01-01

A natural analogue can be defined as a natural process which has occurred in the past and is studied in order to test predictions about the future evolution of similar processes. In recent years, natural analogues have been used increasingly to test the mathematical models required for repository performance assessment. Analogues are, however, also of considerable use in public relations as they allow many of the principles involved in demonstrating repository safety to be illustrated in a clear manner using natural systems with which man is familiar. The international Natural Analogue Working Group (NAWG), organised under the auspices of the CEC, has recognised that such PR applications are of considerable importance and should be supported from a technical level. At the NAWG meeting in Pitlochry, Scotland (June 1990), it was recommended that the possibilities for making a video film on this topic be investigated and Nagra was requested to take the lead role in setting up such a project

Rehearsal in serial memory for visual-spatial information: evidence from eye movements.

Science.gov (United States)

Tremblay, Sébastien; Saint-Aubin, Jean; Jalbert, Annie

2006-06-01

It is well established that rote rehearsal plays a key role in serial memory for lists of verbal items. Although a great deal of research has informed us about the nature of verbal rehearsal, much less attention has been devoted to rehearsal in serial memory for visual-spatial information. By using the dot task--a visual-spatial analogue of the classical verbal serial recall task--with delayed recall, performance and eyetracking data were recorded in order to establish whether visual-spatial rehearsal could be evidenced by eye movement. The use of eye movement as a form of rehearsal is detectable (Experiment 1), and it seems to contribute to serial memory performance over and above rehearsal based on shifts of spatial attention (Experiments 1 and 2).

Fledging in the common swift, Apus apusweight-watching with a difference

Science.gov (United States)

Martins

1997-07-01

Fledging in the common swift involves young having to switch suddenly and completely from the sedentary lifestyle of a nestling to continuous flight with no post-fledging care. Using manipulations of brood size and the contrasting resource conditions in different breeding seasons, I observed fledging under a range of chick states. Poorly fed chicks took longer to fledge, and had lower body mass and short wing length at fledging. Despite this, maximum body mass of nestlings always exceeded those of adults and fledged young. Under all conditions, nestlings lost mass for 1 week prior to fledging, and at fledging they had similar wing loadings. I suggest that in their last days in the nest young swifts use up the fat stores that insured them against irregular parental provisioning as well as losing water from the drying out of feathers. Reductions in body mass associated with increases in wing length before fledging will affect flight efficiency by increasing the lift:drag ratio. This is interpreted as 'slimming' down to the optimal body mass which would improve the lift:drag ratio and set fledgings up for their life on the wing.

Swift J2058.4+0516: Discovery of a Possible Second Relativistic Tidal Disruption Flare

Science.gov (United States)

Cenko, S. Bradely; Krimm, Hans A.; Horesh, Assaf; Rau, Arne; Frail, Dale A.; Kennea, Jamie A.; Levan, Andrew J.; Holland, Stephen T.; Butler, Nathaniel R.; Quimby, Robert M.;

XMM FOLLOW-UP OBSERVATIONS OF THREE SWIFT BAT-SELECTED ACTIVE GALACTIC NUCLEI

International Nuclear Information System (INIS)

Trippe, M. L.; Reynolds, C. S.; Koss, M.; Mushotzky, R. F.; Winter, L. M.

2011-01-01

We present XMM-Newton observations of three active galactic nuclei (AGNs) taken as part of a hunt to find very heavily obscured Compton-thick AGNs. For obscuring columns greater than 10 25 cm -2 , AGNs are only visible at energies below 10 keV via reflected/scattered radiation, characterized by a flat power law. We therefore selected three objects (ESO 417-G006, IRAS 05218-1212, and MCG -01-05-047) from the Swift Burst Alert Telescope (BAT) hard X-ray survey catalog with Swift X-ray Telescope (XRT) 0.5-10 keV spectra with flat power-law indices as candidate Compton-thick sources for follow-up observations with the more sensitive instruments on XMM-Newton. The XMM spectra, however, rule out reflection-dominated models based on the weakness of the observed Fe Kα lines. Instead, the spectra are well fit by a model of a power-law continuum obscured by a Compton-thin absorber plus a soft excess. This result is consistent with previous follow-up observations of two other flat-spectrum BAT-detected AGNs. Thus, out of the six AGNs in the 22 month BAT catalog with apparently flat Swift XRT spectra, all five that have had follow-up observations are not likely Compton thick. We also present new optical spectra of two of these objects, IRAS 05218-1212 and MCG -01-05-047. Interestingly, though both the AGNs have similar X-ray spectra, their optical spectra are completely different, adding evidence against the simplest form of the geometric unified model of AGNs. IRAS 05218-1212 appears in the optical as a Seyfert 1, despite the ∼8.5 x 10 22 cm -2 line-of-sight absorbing column indicated by its X-ray spectrum. MCG -01-05-047's optical spectrum shows no sign of AGN activity; it appears as a normal galaxy.

SWIFT OBSERVATIONS OF HARD X-RAY EMITTING WHITE DWARFS IN SYMBIOTIC STARS

International Nuclear Information System (INIS)

Kennea, J. A.; Burrows, D. N.; Mukai, K.; Markwardt, C. B.; Sokoloski, J. L.; Luna, G. J. M.; Tueller, J.

2009-01-01

The X-ray emission from most accreting white dwarfs (WDs) in symbiotic binary stars is quite soft. Several symbiotic WDs, however, produce strong X-ray emission at energies greater than ∼20 keV. The Swift Burst Alert Telescope (BAT) instrument has detected hard X-ray emission from four such accreting WDs in symbiotic stars: RT Cru, T CrB, CD -57 3057, and CH Cyg. In one case (RT Cru), Swift detected X-rays out to greater than 50 keV at >5σ confidence level. Combining data from the X-Ray Telescope (XRT) and BAT detectors, we find that the 0.3-150 keV spectra of RT Cru, T CrB, and CD -57 3057 are well described by emission from a single-temperature, optically thin thermal plasma, plus an unresolved 6.4-6.9 keV Fe line complex. The X-ray spectrum of CH Cyg contains an additional bright soft component. For all four systems, the spectra suffer high levels of absorption from material that both fully and partially covers the source of hard X-rays. The XRT data did not show any of the rapid, periodic variations that one would expect if the X-ray emission were due to accretion onto a rotating, highly magnetized WD. The X-rays were thus more likely from the accretion-disk boundary layer around a massive, non-magnetic WD in each binary. The X-ray emission from RT Cru varied on timescales of a few days. This variability is consistent with being due to changes in the absorber that partially covers the source, suggesting localized absorption from a clumpy medium moving into the line of sight. The X-ray emission from CD -57 3057 and T CrB also varied during the nine months of Swift observations, in a manner that was also consistent with variable absorption.

Test Plan for the Wake Steering Experiment at the Scaled Wind Farm Technology (SWiFT) Facility.

Energy Technology Data Exchange (ETDEWEB)

Naughton, Brian Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-02-01

This document is a test plan describing the objectives, configuration, procedures, reporting, roles, and responsibilities for conducting the joint Sandia National Laboratories and National Renewable Energy Laboratory Wake Steering Experiment at the Sandia Scaled Wind Farm Technology (SWiFT) facility near Lubbock, Texas in 2016 and 2017 . The purpose of this document is to ensure the test objectives and procedures are sufficiently detailed such that al l involved personnel are able to contribute to the technical success of the test. This document is not intended to address safety explicitly which is addressed in a separate document listed in the references titled Sandia SWiFT Facility Site Operations Manual . Both documents should be reviewed by all test personnel.

Modification of thin-layer systems by swift heavy ions

International Nuclear Information System (INIS)

Bolse, W.; Schattat, B.; Feyh, A.

2003-01-01

The electronic energy loss of swift heavy ions (MeV/amu) within a solid results in a highly excited cylindrical zone of some nm in diameter, within which all atoms may be in motion for some tens of ps (transient local melting). After cooling down, a defect-rich or even amorphous latent track is left in many cases, especially in insulating materials. The resulting property alterations (density, micro-structure, morphology, phase composition, etc.) have been investigated for many bulk materials, while only very few experiments have been carried out with thin-film systems. In the present paper, a summary will be given of our studies on the transport of matter in thin-film packages induced by irradiation with high-energy ions. These is, on the one hand, atomic mixing at the interfaces, which is especially pronounced in ceramic systems and which seems to occur by interdiffusion in the molten ion track. On the other hand, we have discovered a self-organisation phenomenon in swift-heavy-ion-irradiated NiO layers, which at low fluences first showed periodic cracking perpendicular to the projected beam direction. After application of high fluences, the NiO layer was reorganised in 100-nm-thick and 1-μm-high NiO lamellae of the same separation distance (1-3 μm) and orientation as found for the cracks. Both effects can be attributed to transient melting of the material surrounding the ion trajectory. (orig.)

Swift , XMM - Newton , and NuSTAR Observations of PSR J2032+4127/MT91 213

Energy Technology Data Exchange (ETDEWEB)

Li, K. L. [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Kong, A. K. H. [Astrophysics, Department of Physics, University of Oxford, Keble Road, Oxford OX1 3RH (United Kingdom); Tam, P. H. T. [School of Physics and Astronomy, Sun Yat-sen University, Zhuhai 519082 (China); Hou, X. [Yunnan Observatories, Chinese Academy of Sciences, 396 Yangfangwang, Guandu District, Kunming 650216 (China); Takata, J. [Institute of Particle Physics and Astronomy, Huazhong University of Science and Technology (China); Hui, C. Y., E-mail: liliray@pa.msu.edu [Department of Astronomy and Space Science, Chungnam National University, Daejeon (Korea, Republic of)

2017-07-10

We report our recent Swift , NuSTAR , and XMM - Newton X-ray and Lijiang optical observations on PSR J2032+4127/MT91 213, the γ -ray binary candidate with a period of 45–50 years. The coming periastron of the system was predicted to be in 2017 November, around which high-energy flares from keV to TeV are expected. Recent studies with Chandra and Swift X-ray observations taken in 2015/2016 showed that its X-ray emission has been brighter by a factors of ∼10 than that before 2013, probably revealing some ongoing activities between the pulsar wind and the stellar wind. Our new Swift /XRT lightcurve shows no strong evidence of a single vigorous brightening trend, but rather several strong X-ray flares on weekly to monthly timescales with a slowly brightening baseline, namely the low state. The NuSTAR and XMM - Newton observations taken during the flaring and the low states, respectively, show a denser environment and a softer power-law index during the flaring state, implying that the pulsar wind interacted with the stronger stellar winds of the companion to produce the flares. These precursors would be crucial in studying the predicted giant outburst from this extreme γ -ray binary during the periastron passage in late 2017.

Analogue Hawking radiation from astrophysical black-hole accretion

International Nuclear Information System (INIS)

Das, Tapas K

2004-01-01

We show that spherical accretion onto astrophysical black holes can be considered as a natural example of an analogue system. We provide, for the first time, an exact analytical scheme for calculating the analogue Hawking temperature and surface gravity for general relativistic accretion onto astrophysical black holes. Our calculation may bridge the gap between the theory of transonic astrophysical accretion and the theory of analogue Hawking radiation. We show that the domination of the analogue Hawking temperature over the actual Hawking temperature may be a real astrophysical phenomenon, though observational tests of this fact will at best be difficult and at worst might prove to be impossible. We also discuss the possibilities of the emergence of analogue white holes around astrophysical black holes. Our calculation is general enough to accommodate accreting black holes with any mass

THE PROBLEM OF GENRE DEFINING WORKS OF D.DEFOE AND J.SWIFT

Directory of Open Access Journals (Sweden)

M. A. Maslova

2014-01-01

Full Text Available The article addresses the question of genre specifics of works D.Defoe and J.Swift. Novels of English writers of the 18th century are presented as a synthesis of various genre models: travel, adventure, philosophical novel, an allegorical parable, satire, utopia. The emphasis is on the analysis of the philosophical content of the novels.

Searching for the Hebb Effect in down Syndrome: Evidence for a Dissociation between Verbal Short-Term Memory and Domain-General Learning of Serial Order

Science.gov (United States)

Mosse, E. K.; Jarrold, C.

2010-01-01

Background: The Hebb effect is a form of repetition-driven long-term learning that is thought to provide an analogue for the processes involved in new word learning. Other evidence suggests that verbal short-term memory also constrains now vocabulary acquisition, but if the Hebb effect is independent of short-term memory, then it may be possible…

The Swift Project Contamination Control Program: A Case Study of Balancing Cost, Schedule and Risk

Science.gov (United States)

Hansen, Patricia A.; Day, Diane T.; Secunda, Mark S.; Rosecrans, Glenn P.

2004-01-01

The Swift Observatory will be launched in early 2004 to examine the dynamic process of gamma ray burst (GRB) events. The multi-wavelength Observatory will study the GRB afterglow characteristics, which will help to answer fundamental questions about both the structure and the evolution of the universe. The Swift Observatory Contamination Control Program has been developed to aid in ensuring the success of the on-orbit performance of two of the primary instruments: the Ultraviolet and Optical Telescope (UVOT) and the X-Ray Telescope (XRT). During the design phase of the Observatory, the contamination control program evolved and trade studies were performed to assess the risk of contaminating the sensitive UVOT and XRT optics during both pre-launch testing and on-orbit operations, within the constraints of the overall program cost and schedule.

IMATERALISASI JAMINAN BENDA DALAM BENTUK CASH COLLATERAL SEBAGAI JAMINAN PROYEK INFRA STRUKTUR MELALUI MEKANISME SWIFT

Directory of Open Access Journals (Sweden)

Tarsisius Murwaji

2013-10-01

Full Text Available The construction of infrastructure projects require large expenses. The cost for the project loan is usually derived from international banks. Legal issues, among others: we do not guarantee the legal system conducive to use in large financing; corporate body and banking institutions we considered to be of international standard, and our le-gal system is regarded as the country risk. The other hand many people of Indonesia who have collateral material, usually pure gold (precious metals that have been diimaterialization and included in the accounts of foreign banks. Such guarantees may be used as the basis of the issuance of bank guarantees and through the mechanism of Society Worldwide Interbank Financial Telecommunications (SWIFT can be used as loan collateral banks in Indonesia. Key words: bank guaranty, SWIFT, security law, international banking system

DO THE FERMI GAMMA-RAY BURST MONITOR AND SWIFT BURST ALERT TELESCOPE SEE THE SAME SHORT GAMMA-RAY BURSTS?

International Nuclear Information System (INIS)

Burns, Eric; Briggs, Michael S.; Connaughton, Valerie; Zhang, Bin-Bin; Lien, Amy; Goldstein, Adam; Pelassa, Veronique; Troja, Eleonora

2016-01-01

Compact binary system mergers are expected to generate gravitational radiation detectable by ground-based interferometers. A subset of these, the merger of a neutron star with another neutron star or a black hole, are also the most popular model for the production of short gamma-ray bursts (GRBs). The Swift Burst Alert Telescope (BAT) and the Fermi Gamma-ray Burst Monitor (GBM) trigger on short GRBs (SGRBs) at rates that reflect their relative sky exposures, with the BAT detecting 10 per year compared to about 45 for GBM. We examine the SGRB populations detected by Swift BAT and Fermi GBM. We find that the Swift BAT triggers on weaker SGRBs than Fermi GBM, providing they occur close to the center of the BAT field of view, and that the Fermi GBM SGRB detection threshold remains flatter across its field of view. Overall, these effects combine to give the instruments the same average sensitivity, and account for the SGRBs that trigger one instrument but not the other. We do not find any evidence that the BAT and GBM are detecting significantly different populations of SGRBs. Both instruments can detect untriggered SGRBs using ground searches seeded with time and position. The detection of SGRBs below the on-board triggering sensitivities of Swift BAT and Fermi GBM increases the possibility of detecting and localizing the electromagnetic counterparts of gravitational wave (GW) events seen by the new generation of GW detectors

DO THE FERMI GAMMA-RAY BURST MONITOR AND SWIFT BURST ALERT TELESCOPE SEE THE SAME SHORT GAMMA-RAY BURSTS?

Energy Technology Data Exchange (ETDEWEB)

Burns, Eric; Briggs, Michael S. [University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Connaughton, Valerie [Universities Space Research Association, Science and Technology Institute, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Zhang, Bin-Bin [Center for Space Plasma and Aeronomic Research (CSPAR), University of Alabama in Huntsville, Huntsville, AL 35899 (United States); Lien, Amy [Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Goldstein, Adam [NASA Postdoctoral Program, Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Pelassa, Veronique [Smithsonian Astrophysical Observatory, P.O. Box 97, Amado, AZ 85645 (United States); Troja, Eleonora, E-mail: eb0016@uah.edu [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

2016-02-20

Compact binary system mergers are expected to generate gravitational radiation detectable by ground-based interferometers. A subset of these, the merger of a neutron star with another neutron star or a black hole, are also the most popular model for the production of short gamma-ray bursts (GRBs). The Swift Burst Alert Telescope (BAT) and the Fermi Gamma-ray Burst Monitor (GBM) trigger on short GRBs (SGRBs) at rates that reflect their relative sky exposures, with the BAT detecting 10 per year compared to about 45 for GBM. We examine the SGRB populations detected by Swift BAT and Fermi GBM. We find that the Swift BAT triggers on weaker SGRBs than Fermi GBM, providing they occur close to the center of the BAT field of view, and that the Fermi GBM SGRB detection threshold remains flatter across its field of view. Overall, these effects combine to give the instruments the same average sensitivity, and account for the SGRBs that trigger one instrument but not the other. We do not find any evidence that the BAT and GBM are detecting significantly different populations of SGRBs. Both instruments can detect untriggered SGRBs using ground searches seeded with time and position. The detection of SGRBs below the on-board triggering sensitivities of Swift BAT and Fermi GBM increases the possibility of detecting and localizing the electromagnetic counterparts of gravitational wave (GW) events seen by the new generation of GW detectors.

Recrystallization effects of swift heavy {sup 209}Bi ions irradiation on electrical degradation in 4H-SiC Schottky barrier diode

Energy Technology Data Exchange (ETDEWEB)

Yang, Zhimei; Ma, Yao; Gong, Min [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China); Key Laboratory of Radiation Physics and Technology of Ministry of Education, Sichuan University, Chengdu 610064 (China); Li, Yun [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China); Huang, Mingmin [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China); Key Laboratory of Radiation Physics and Technology of Ministry of Education, Sichuan University, Chengdu 610064 (China); Gao, Bo [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China); Zhao, Xin, E-mail: zhaoxin1234@scu.edu.cn [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China)

2017-06-15

In this paper, the phenomenon that the recrystallization effects of swift heavy {sup 209}Bi ions irradiation can partially recovery damage with more than 1 × 10{sup 10} ions/cm{sup 2} is investigated by the degradation of the electrical characteristics of 4H-SiC Schottky barrier diode (SBD) with swift heavy ion irradiation. Deep level transient spectroscopy (DLTS) and Current-Voltage (I-V) measurements clearly indicated that E{sub 0.62} defect induced by swift heavy ion irradiation, which was a recombination center, could result in the increase of reverse leakage current (I{sub R}) at fluence less than 1 × 10{sup 9} ions/cm{sup 2} and the recovery of I{sub R} at fluence more than 1 × 10{sup 10} ions/cm{sup 2} in 4H-SiC SBD. The variation tendency of I{sub R} is consisted with the change of E{sub 0.62} defect. Furthermore, it is reasonable explanation that the damage or defect formed at low fluence in SiC may be recovered by further swift heavy ion irradiation with high fluence, which is due to the melting with the ion tracks of the amorphous zones through a thermal spike and subsequent epitaxial recrystallization initiated from the neighboring crystalline regions.

The hard X-ray spectrum of MAXI J1820+070 observed by Swift/BAT

Science.gov (United States)

Del Santo, Melania; Segreto, Alberto

2018-03-01

We have analysed the Swift/BAT data of the new transient MAXI J1820+070 (Atel #11399,#11400, #11403, #11404, #11406, #11418, #11420, #11421, #11423,#11424, #11425, #11425) collected from 2018-03-07 00:41:07 until 2018-03-15 06:20:58.

Nucleation of 2D nanoislands in surface thermal spikes from swift heavy ions

International Nuclear Information System (INIS)

Volkov, Alexander E.; Sorokin, Michael V.

2003-01-01

Possibility of nucleation of nanoislands in the surface thermal spikes caused by swift heavy ions or intense femptosecond laser pulses is investigated. Nanoislands may occur when the characteristic nucleation time becomes shorter than that cooling down of the thermal spot. The values of system parameters favorable for the nucleation are estimated

Irradiation effects of swift heavy ions in matter

Energy Technology Data Exchange (ETDEWEB)

Osmani, Orkhan

2011-12-22

In the this thesis irradiation effects of swift heavy ions in matter are studied. The focus lies on the projectiles charge exchange and energy loss processes. A commonly used computer code which employs rate equations is the so called ETACHA code. This computer code is capable to also calculate the required input cross-sections. Within this thesis a new model to compute the charge state of swift heavy ions is explored. This model, the so called matrix method, takes the form of a simple algebraic expression, which also requires cross-sections as input. In the present implementation of the matrix method, cross-sections are taken from the ETACHA code, while excitation and deexcitation processes are neglected. Charge fractions for selected ion/target combinations, computed by the ETACHA code and the matrix method are compared. It is shown, that for sufficient large ion energies, both methods agree very well with each other. However, for lower energies pronounced differences are observed. These differences are believed to stem from the fact, that no excited states as well as the decay of theses excited states are included in the present implementation of the matrix method. Both methods are then compared with experimental measurements, where significant deviations are observed for both methods. While the predicted equilibrium charge state by both methods is in good agreement with the experiments, the matrix method predicts a much too large equilibrium thickness compared to both the ETACHA calculation as well as the experiment. Again, these deviations are believed to stem from the fact, that excitation and the decay of excited states are not included in the matrix method. A possible way to include decay processes into the matrix method is presented, while the accuracy of the applied capture cross-sections is tested by comparison with scaling rules. Swift heavy ions penetrating a dielectric are known to induced structural modifications both on the surface and in the bulk

Irradiation effects of swift heavy ions in matter

International Nuclear Information System (INIS)

Osmani, Orkhan

2011-01-01

In the this thesis irradiation effects of swift heavy ions in matter are studied. The focus lies on the projectiles charge exchange and energy loss processes. A commonly used computer code which employs rate equations is the so called ETACHA code. This computer code is capable to also calculate the required input cross-sections. Within this thesis a new model to compute the charge state of swift heavy ions is explored. This model, the so called matrix method, takes the form of a simple algebraic expression, which also requires cross-sections as input. In the present implementation of the matrix method, cross-sections are taken from the ETACHA code, while excitation and deexcitation processes are neglected. Charge fractions for selected ion/target combinations, computed by the ETACHA code and the matrix method are compared. It is shown, that for sufficient large ion energies, both methods agree very well with each other. However, for lower energies pronounced differences are observed. These differences are believed to stem from the fact, that no excited states as well as the decay of theses excited states are included in the present implementation of the matrix method. Both methods are then compared with experimental measurements, where significant deviations are observed for both methods. While the predicted equilibrium charge state by both methods is in good agreement with the experiments, the matrix method predicts a much too large equilibrium thickness compared to both the ETACHA calculation as well as the experiment. Again, these deviations are believed to stem from the fact, that excitation and the decay of excited states are not included in the matrix method. A possible way to include decay processes into the matrix method is presented, while the accuracy of the applied capture cross-sections is tested by comparison with scaling rules. Swift heavy ions penetrating a dielectric are known to induced structural modifications both on the surface and in the bulk

Synthesis and biological evaluation of febrifugine analogues.

Science.gov (United States)

Mai, Huong Doan Thi; Thanh, Giang Vo; Tran, Van Hieu; Vu, Van Nam; Vu, Van Loi; Le, Cong Vinh; Nguyen, Thuy Linh; Phi, Thi Dao; Truong, Bich Ngan; Chau, Van Minh; Pham, Van Cuong

2014-12-01

A series of febrifugine analogues were designed and synthesized. Antimalarial activity evaluation of the synthetic compounds indicated that these derivatives had a strong inhibition against both chloroquine-sensitive and -resistant Plasmodium falciparum parasites. Many of them were found to be more active than febrifugine hydrochloride. The tested analogues had also a significant cytotoxicity against four cancer cell lines (KB, MCF7, LU1 and HepG2). Among the synthetic analogues, two compounds 17b and 17h displayed a moderate cytotoxicity while they exhibited a remarkable antimalarial activity.

Assessment of six dissimilarity metrics for climate analogues

Science.gov (United States)

Grenier, Patrick; Parent, Annie-Claude; Huard, David; Anctil, François; Chaumont, Diane

2013-04-01

Spatial analogue techniques consist in identifying locations whose recent-past climate is similar in some aspects to the future climate anticipated at a reference location. When identifying analogues, one key step is the quantification of the dissimilarity between two climates separated in time and space, which involves the choice of a metric. In this communication, spatial analogues and their usefulness are briefly discussed. Next, six metrics are presented (the standardized Euclidean distance, the Kolmogorov-Smirnov statistic, the nearest-neighbor distance, the Zech-Aslan energy statistic, the Friedman-Rafsky runs statistic and the Kullback-Leibler divergence), along with a set of criteria used for their assessment. The related case study involves the use of numerical simulations performed with the Canadian Regional Climate Model (CRCM-v4.2.3), from which three annual indicators (total precipitation, heating degree-days and cooling degree-days) are calculated over 30-year periods (1971-2000 and 2041-2070). Results indicate that the six metrics identify comparable analogue regions at a relatively large scale, but best analogues may differ substantially. For best analogues, it is also shown that the uncertainty stemming from the metric choice does generally not exceed that stemming from the simulation or model choice. A synthesis of the advantages and drawbacks of each metric is finally presented, in which the Zech-Aslan energy statistic stands out as the most recommended metric for analogue studies, whereas the Friedman-Rafsky runs statistic is the least recommended, based on this case study.

SWIFT J1749.4-2807 : X-ray decay, refined position and optical observation

NARCIS (Netherlands)

Yang, Y.J.; Russell, D. M.; Wijnands, R.; van der Klis, M.; Altamirano, D.; Patruno, A.; Watts, A.; Armas Padilla, M.; Cavecchi, Y.; Degenaar, N.; Kalamkar, M.; Kaur, R.; Linares, M.; Casella, P.; Rea, N.; Soleri, P.; Lewis, F.; Kong, A. K. H.

We analyzed seven, target ID 31686, Swift follow-up observations of the neutron-star X-ray transient Swfit J1749.4-2807 (Wijnands et al. 2009) currently in outburst and which was found to be an accreting millisecond X-ray pulsar (ATel #2565). The observations span from April 11 to April 20.

AGN classification for X-ray sources in the 105 month Swift/BAT survey

Science.gov (United States)

Masetti, N.; Bassani, L.; Palazzi, E.; Malizia, A.; Stephen, J. B.; Ubertini, P.

2018-03-01

We here provide classifications for 8 hard X-ray sources listed as 'unknown AGN' in the 105 month Swift/BAT all-sky survey catalogue (Oh et al. 2018, ApJS, 235, 4). The corresponding optical spectra were extracted from the 6dF Galaxy Survey (Jones et al. 2009, MNRAS, 399, 683).

Synthesis and anticancer evaluation of spermatinamine analogues

KAUST Repository

Moosa, Basem; Sagar, Sunil; Li, Song; Esau, Luke; Kaur, Mandeep; Khashab, Niveen M.

2016-01-01

analogues and their cytotoxic evaluation against three human cancer cell lines i.e. cervix adenocarcinoma (HeLa), breast adenocarcinoma (MCF-7), and prostate carcinoma (DU145). Analogues 12, 14 and 15 were found to be the most potent against one or more cell

Insulin analogues in pregnancy and specific congenital anomalies

DEFF Research Database (Denmark)

de Jong, Josta; Garne, Ester; Wender-Ozegowska, Ewa

2016-01-01

Insulin analogues are commonly used in pregnant women with diabetes. It is not known if the use of insulin analogues in pregnancy is associated with any higher risk of congenital anomalies in the offspring compared with use of human insulin. We performed a literature search for studies of pregnant...... women with pregestational diabetes using insulin analogues in the first trimester and information on congenital anomalies. The studies were analysed to compare the congenital anomaly rate among foetuses of mothers using insulin analogues with foetuses of mothers using human insulin. Of 29 studies, we...... samples in the included studies provided insufficient statistical power to identify a moderate increased risk of specific congenital anomalies. Copyright © 2015 John Wiley & Sons, Ltd....

Glucagon-like peptide-1 analogues: An overview

Directory of Open Access Journals (Sweden)

Vishal Gupta

2013-01-01

Full Text Available Abnormalities of the incretin axis have been implicated in the pathogenesis of type 2 diabetes mellitus. Glucagon-like peptide-1 (GLP-1 and gastroinhibitory intestinal peptide constitutes >90% of all the incretin function. Augmentation of GLP-1 results in improvement of beta cell health in a glucose-dependant manner (post-prandial hyperglycemia and suppression of glucagon (fasting hyperglycemia, amongst other beneficial pleiotropic effects. Native GLP-1 has a very short plasma half-life and novel methods have been developed to augment its half life, such that its anti-hyperglycemic effects can be exploited. They can be broadly classified as exendin-based therapies (exenatide, exenatide once weekly, DPP-4-resistant analogues (lixisenatide, albiglutide, and analogues of human GLP-1 (liraglutide, taspoglutide. Currently, commercially available analogues are exenatide, exenatide once weekly, and liraglutide. This review aims to provide an overview of most GLP-1 analogues.

Analogue circuits simulation

Energy Technology Data Exchange (ETDEWEB)

Mendo, C

1988-09-01

Most analogue simulators have evolved from SPICE. The history and description of SPICE-like simulators are given. From a mathematical formulation of the electronic circuit the following analysis are possible: DC, AC, transient, noise, distortion, Worst Case and Statistical.

Uncertainties and credibility building of safety analyses. Natural analogues

International Nuclear Information System (INIS)

Laciok, A.

2001-07-01

The substance of natural analogues and their studies is defined as a complementary method to laboratory and in-situ experiments and modelling. The role of natural analogues in the processes of development of repositories is defined, mainly in performance assessment of repository system and communication with public. The criteria for identification of natural analogues which should be evaluated in the phase of initiation of new studies are specified. Review part of this report is divided to study of natural analogues and study of anthropogenic and industrial analogues. The main natural analogue studies performed in various countries, in different geological setting, with various aims are characterized. New results acquired in recently finished studies are included: Palmottu (2nd phase of project financed by European Commission), Oklo (results of research financed also by European Commission), Maqarin (3rd phase) and other information obtained from last meetings and workshops of NAWG. In view of the fact that programmes of development of deep repositories in Czech and Slovak Republics are interconnected, the natural analogues studies carried out in the Czech republic are incorporated in separate chapter - study of uranium accumulation in Tertiary clays at Ruprechtov site and study of degradation of natural glasses. In final part the areas of natural analogue studies as an integral part of development of deep geological repository are proposed along with characterization of broader context and aspects of realization of these studies (international cooperation, preparation and evaluation of procedures, communication with public). (author)

Revisiting galactic black hole binary GX 339-4 by using 2007 – 2014 Swift XRT observations

International Nuclear Information System (INIS)

Azizi, Febrie Ahmad; Vierdayanti, Kiki; Putra, Mahasena

2015-01-01

This work aims to study the X-ray properties of the galactic black hole binary GX 339-4. Focus of the study is on exploration of data from Swift-XRT in exclusively photon-counting mode. We use data from 2007 up to August 2014, which contain about 40 pointing observations with level 1 data. The flux of GX 339-4 varies in a factor of 100 during this period of observations. For the purpose of this work, we also try to develop a system to conduct standard SWIFT XRT data reduction automatically, in order to greatly reduce time when working with data bulk, which produces images, lightcurves as well as spectra. We also develop another system to conduct fitting of bulk spectral data with a two-component model, disk blackbody and power-law. The fitting results show that no data have a reduced chi-squared > 2. The fraction of the disk to total flux and the power-law to total flux range from 0.00389 – 0.994 and 0.00605 – 0.996, respectively. From the analysis of the disk component, we obtain the value of the innermost disk radius that does not show any large scale truncation which is in a good agreement with a previous study that used 2007 – 2011 Swift-XRT data, indicating that the systems we developed work properly

ACTINOMYCIN D ANALOGUES

DEFF Research Database (Denmark)

1997-01-01

The present invention relates to new compounds being structurally and functionally similar to Actinomycin D and to combinatorial libraries of such compounds. The Actinomycin D analogues according to the present invention comprise two linear or cyclic peptide moieties constituted by $g...

Introduction to electronic analogue computers

CERN Document Server

Wass, C A A

1965-01-01

Introduction to Electronic Analogue Computers, Second Revised Edition is based on the ideas and experience of a group of workers at the Royal Aircraft Establishment, Farnborough, Hants. This edition is almost entirely the work of Mr. K. C. Garner, of the College of Aeronautics, Cranfield. As various advances have been made in the technology involving electronic analogue computers, this book presents discussions on the said progress, including some acquaintance with the capabilities of electronic circuits and equipment. This text also provides a mathematical background including simple differen

Femto-clock for the electron kinetics in swift heavy ion tracks

Czech Academy of Sciences Publication Activity Database

Medvedev, Nikita; Volkov, A.E.

2017-01-01

Roč. 50, č. 44 (2017), s. 1-11, č. článku 445302. ISSN 0022-3727 R&D Projects: GA MŠk LG15013; GA MŠk(CZ) LM2015083 Institutional support: RVO:68378271 Keywords : swift heavy ions * electron kinetics * femto-clock * femtosecond resolution * spectroscopy * radiative decay Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) Impact factor: 2.588, year: 2016

Deep NuSTAR and Swift monitoring observations of the magnetar 1E 1841-045

DEFF Research Database (Denmark)

An, Hongjun; Archibald, Robert F.; Hascoët, Romain

2015-01-01

consistent with the footprint of the twisted magnetic field lines on the star. We also report on the 3 yr Swift monitoring observations obtained since 2011 July. The soft-X-ray spectrum remained stable during this period, and the timing behavior was noisy, with large timing residuals....

The Influence of Thought Suppression and Cognitive Load on Intrusions and Memory Processes following an Analogue Stressor

Science.gov (United States)

Nixon, Reginald D. V.; Cain, Neralie; Nehmy, Thomas; Seymour, Melanie

2009-01-01

Ironic Process Theory and the role of thought suppression have been used in part to explain the phenomenon of intrusive memories in various disorders, including posttraumatic stress disorder. How thought suppression interacts with other cognitive processes believed to be instrumental in the development of traumatic intrusive memory is unclear. In…

Defects induced magnetic transition in Co doped ZnS thin films: Effects of swift heavy ion irradiations

Energy Technology Data Exchange (ETDEWEB)

Patel, Shiv P., E-mail: shivpoojanbhola@gmail.com [Physics Department, University of Allahabad, Allahabad 211002 (India); Pivin, J.C. [CSNSM, IN2P3-CNRS, Batiment 108, F-91405 Orsay Campus (France); Patel, M.K; Won, Jonghan [Materials Science and Technology Division, MST-8, P.O.Box 1663, Mail Stop G755, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Chandra, Ramesh [Nanoscience Laboratory, IIC, Indian Institute of Technology, Roorkee 247667 (India); Kanjilal, D. [Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India); Kumar, Lokendra [Physics Department, University of Allahabad, Allahabad 211002 (India)

2012-07-15

The effect of swift heavy ions (SHI) on magnetic ordering in ZnS thin films with Co ions substituted on Zn sites is investigated. The materials have been synthesized by pulsed laser deposition on substrates held at 600 Degree-Sign C for obtaining films with wurtzite crystal structure and it showed ferromagnetic ordering up to room temperature with a paramagnetic component. 120 MeV Ag ions have been used at different fluences of 1 Multiplication-Sign 10{sup 11} ions/cm{sup 2} and 1 Multiplication-Sign 10{sup 12} ions/cm{sup 2} for SHI induced modifications. The long range correlation between paramagnetic spins on Co ions was destroyed by irradiation and the material became purely paramagnetic. The effect is ascribed to the formation of cylindrical ion tracks due to the thermal spikes resulting from electron-phonon coupling. - Highlights: Black-Right-Pointing-Pointer Effect of swift heavy ions on magnetic ordering in Co doped ZnS thin films are presented. Black-Right-Pointing-Pointer Magnetization in the pristine films is composed of ferromagnetic and paramagnetic components. Black-Right-Pointing-Pointer The films become purely paramagnetic after swift heavy ions irradiation. Black-Right-Pointing-Pointer The magnetic transition is ascribed to the formation of ion track (or cylindrical defects) due to the thermal spikes.

Swift heavy ion irradiation of CaF2 - from grooves to hillocks in a single ion track

Science.gov (United States)

Gruber, Elisabeth; Salou, Pierre; Bergen, Lorenz; El Kharrazi, Mourad; Lattouf, Elie; Grygiel, Clara; Wang, Yuyu; Benyagoub, Abdenacer; Levavasseur, Delphine; Rangama, Jimmy; Lebius, Henning; Ban-d'Etat, Brigitte; Schleberger, Marika; Aumayr, Friedrich

2016-10-01

A novel form of ion-tracks, namely nanogrooves and hillocks, are observed on CaF2 after irradiation with xenon and lead ions of about 100 MeV kinetic energy. The irradiation is performed under grazing incidence (0.3°-3°) which forces the track to a region in close vicinity to the surface. Atomic force microscopy imaging of the impact sites with high spatial resolution reveals that the surface track consists in fact of three distinct parts: each swift heavy ion impacting on the CaF2 surface first opens a several 100 nm long groove bordered by a series of nanohillocks on both sides. The end of the groove is marked by a huge single hillock and the further penetration of the swift projectile into deeper layers of the target is accompanied by a single protrusion of several 100 nm in length slowly fading until the track vanishes. By comparing experimental data for various impact angles with results of a simulation, based on a three-dimensional version of the two-temperature-model (TTM), we are able to link the crater and hillock formation to sublimation and melting processes of CaF2 due to the local energy deposition by swift heavy ions.

Performance evaluation of the analogue front-end and ADC prototypes for the Gotthard-II development

Science.gov (United States)

Zhang, J.; Andrä, M.; Barten, R.; Bergamaschi, A.; Brückner, M.; Dinapoli, R.; Fröjdh, E.; Greiffenberg, D.; Lopez-Cuenca, C.; Mezza, D.; Mozzanica, A.; Ramilli, M.; Redford, S.; Ruat, M.; Ruder, C.; Schmitt, B.; Shi, X.; Thattil, D.; Tinti, G.; Turcato, M.; Vetter, S.

2017-12-01

Gotthard-II is a silicon microstrip detector developed for the European X-ray Free-Electron Laser (XFEL.EU). Its potential scientific applications include X-ray absorption/emission spectroscopy, hard X-ray high resolution single-shot spectrometry (HiREX), energy dispersive experiments at 4.5 MHz frame rate, beam diagnostics, as well as veto signal generation for pixel detectors. Gotthard-II uses a silicon microstrip sensor with a pitch of 50 μm or 25 μm and with 1280 or 2560 channels wire-bonded to readout chips (ROCs). In the ROC, an adaptive gain switching pre-amplifier (PRE), a fully differential Correlated-Double-Sampling (CDS) stage, an Analog-to-Digital Converter (ADC) as well as a Static Random-Access Memory (SRAM) capable of storing all the 2700 images in an XFEL.EU bunch train will be implemented. Several prototypes with different designs of the analogue front-end (PRE and CDS) and ADC test structures have been fabricated in UMC-110 nm CMOS technology and their performance has been evaluated. In this paper, the performance of the analogue front-end and ADC will be summarized.

In vitro structure-activity relationship of Re-cyclized octreotide analogues

Energy Technology Data Exchange (ETDEWEB)

Dannoon, Shorouk F. [Department of Chemistry, University of Missouri, Columbia, MO 65211 (United States); Bigott-Hennkens, Heather M. [Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211 (United States); Ma Lixin [Department of Radiology, University of Missouri, Columbia, MO 65211 (United States); International Institute of Nano and Molecular Medicine, University of Missouri, Columbia, MO 65211 (United States); Nuclear Science and Engineering Institute, University of Missouri, Columbia, MO 65211 (United States); Research Service, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201 (United States); Gallazzi, Fabio [Structural Biology Core, University of Missouri, Columbia, MO 65211 (United States); Lewis, Michael R., E-mail: lewismic@missouri.ed [Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211 (United States); Department of Radiology, University of Missouri, Columbia, MO 65211 (United States); Nuclear Science and Engineering Institute, University of Missouri, Columbia, MO 65211 (United States); Research Service, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201 (United States); Jurisson, Silvia S., E-mail: jurissons@missouri.ed [Department of Chemistry, University of Missouri, Columbia, MO 65211 (United States); Department of Radiology, University of Missouri, Columbia, MO 65211 (United States); Nuclear Science and Engineering Institute, University of Missouri, Columbia, MO 65211 (United States)

2010-07-15

Introduction: Development of radiolabeled octreotide analogues is of interest for targeting somatostatin receptor (SSTR)-positive tumors for diagnostic and therapeutic purposes. We are investigating a direct labeling approach for incorporation of a Re ion into octreotide analogues, where the peptide sequences are cyclized via coordination to Re rather than through a disulfide bridge. Methods: Various octreotide analogue sequences and coordination systems (e.g., S{sub 2}N{sub 2} and S{sub 3}N) were synthesized and cyclized with nonradioactive Re. In vitro competitive binding assays with {sup 111}In-DOTA-Tyr{sup 3}-octreotide in AR42J rat pancreatic tumor cells yielded IC{sub 50} values as a measure of SSTR affinity of the Re-cyclized analogues. Three-dimensional structures of Re-cyclized Tyr{sup 3}-octreotate and its disulfide-bridged analogue were calculated from two-dimensional NMR experiments to visualize the effect of metal cyclization on the analogue's pharmacophore. Results: Only two of the 11 Re-cyclized analogues investigated showed moderate in vitro binding affinity toward somatostatin subtype 2 receptors. Three-dimensional molecular structures of Re- and disulfide-cyclized Tyr{sup 3}-octreotate were calculated, and both of their pharmacophore turns appear to be very similar with minor differences due to metal coordination to the amide nitrogen of one of the pharmacophore amino acids. Conclusions: Various Re-cyclized analogues were developed and analogue 4 had moderate affinity toward somatostatin subtype 2 receptors. In vitro stable studies that are in progress showed stable radiometal cyclization of octreotide analogues via NS{sub 3} and N{sub 2}S{sub 2} coordination forming five- and six-membered chelate rings. In vivo biodistribution studies are underway of {sup 99m}Tc-cyclized analogue 4.

Finite element simulation of texture evolution and Swift effect in NiAl under torsion

Science.gov (United States)

Böhlke, Thomas; Glüge, Rainer; Klöden, Burghardt; Skrotzki, Werner; Bertram, Albrecht

2007-09-01

The texture evolution and the Swift effect in NiAl under torsion at 727 °C are studied by finite element simulations for two different initial textures. The material behaviour is modelled by an elastic-viscoplastic Taylor model. In order to overcome the well-known shortcomings of Taylor's approach, the texture evolution is also investigated by a representative volume element (RVE) with periodic boundary conditions and a compatible microstructure at the opposite faces of the RVE. Such a representative volume element takes into account the grain morphology and the grain interaction. The numerical results are compared with experimental data. It is shown that the modelling of a finite element based RVE leads to a better prediction of the final textures. However, the texture evolution path is not accounted for correctly. The simulated Swift effect depends much more on the initial orientation distribution than observed in experiment. Deviations between simulation and experiment may be due to continuous dynamic recrystallization.

Searches for hard X-ray gamma-ray burst afterglows with the BAT on Swift

International Nuclear Information System (INIS)

Krimm, Hans A.; Ozawa, Hideki; Weidenspointner, Georg; Barbier, Louis M.; Barthelmy, Scott D.; Gehrels, Neil; Parsons, Ann M.; Tueller, Jack; Eftekharzadeh, Ardeshir; Hullinger, Derek D.; Markwardt, Craig; Fenimore, Edward E.; Palmer, David M.

2003-01-01

The Burst Alert Telescope (BAT) on the Swift gamma ray burst mission will continue to observe the fields of all detected gamma-ray bursts for several days after the prompt emission has faded. Utilizing first event-by-event data, then one minute and later five minute survey accumulations, the BAT will be extremely sensitive to the hard X-ray afterglow known to be associated with many bursts. This data will cover the crucial transition of the afterglow from rapid variability to the smoothly decaying power law in time and will extend observations of the tails of individual bursts to longer time scales than have been achievable so far. Since Swift is sensitive to short duration GRBs, we will also be able to determine whether hard X-ray afterglows are associated with short GRBs. The BAT will provide high resolution spectra of burst afterglows, allowing us to study in detail the time evolution of GRB spectra

Emerging Forms of the Part II of Jonathan Swift's Novel “Gulliver’s Travels”

Directory of Open Access Journals (Sweden)

Svitlana Tikhonenko

2017-11-01

Full Text Available The article is devoted to the study of grotesque forms in Jonathan Swift's novel "Gulliver’s Travels" based on the text of part II of the novel "A Voyage to Brobdingnag". On the basis of the selected actual material, displays of the grotesque elements in the semantic field of the work’s text are traced. The grotesque world of the novel is the author's model of mankind, in which J. Swift presents his view not only on the state of the modern system of England, but also on the nature of man in general, reveals the peculiarities of the psychology of human nature, especially human socialization. In part II, the author continues to develop a complex and contradictory picture of human existence in front of the reader, the world of giants appears as an ambivalent system in which the features of an ideal society and ideal ruler, in author’s opinion, with the ugly face of man and society, are marvelously combined.

A novel lunar bed rest analogue.

Science.gov (United States)

Cavanagh, Peter R; Rice, Andrea J; Licata, Angelo A; Kuklis, Matthew M; Novotny, Sara C; Genc, Kerim O; Englehaupt, Ricki K; Hanson, Andrea M

2013-11-01

Humans will eventually return to the Moon and thus there is a need for a ground-based analogue to enable the study of physiological adaptations to lunar gravity. An important unanswered question is whether or not living on the lunar surface will provide adequate loading of the musculoskeletal system to prevent or attenuate the bone loss that is seen in microgravity. Previous simulations have involved tilting subjects to an approximately 9.5 degrees angle to achieve a lunar gravity component parallel to the long-axis of the body. However, subjects in these earlier simulations were not weight-bearing, and thus these protocols did not provide an analogue for load on the musculoskeletal system. We present a novel analogue which includes the capability to simulate standing and sitting in a lunar loading environment. A bed oriented at a 9.5 degrees angle was mounted on six linear bearings and was free to travel with one degree of freedom along rails. This allowed approximately 1/6 body weight loading of the feet during standing. "Lunar" sitting was also successfully simulated. A feasibility study demonstrated that the analogue was tolerated by subjects for 6 d of continuous bed rest and that the reaction forces at the feet during periods of standing were a reasonable simulation of lunar standing. During the 6 d, mean change in the volume of the quadriceps muscles was -1.6% +/- 1.7%. The proposed analogue would appear to be an acceptable simulation of lunar gravity and deserves further exploration in studies of longer duration.

The First Simultaneous Microlensing Observations by Two Space Telescopes: Spitzer and Swift Reveal a Brown Dwarf in Event OGLE-2015-BLG-1319

Science.gov (United States)

Shvartzvald, Y.; Li, Z.; Udalski, A.; Gould, A.; Sumi, T.; Street, R. A.; Calchi Novati, S.; Hundertmark, M.; Bozza, V.; Beichman, C.;

Fermi and Swift as supernova alarms: Alert, localization, and diagnosis of future Galactic Type Ia explosions

Science.gov (United States)

Wang, Xilu; Fields, Brian D.; Lien, Amy Y.

2017-01-01

A Galactic SNIa event could go entirely unnoticed due to the large optical and near-IR extinction in the Milky Way plane, low radio and X-ray luminosities, and a weak neutrino signal. But the recent SN2014J confirms that Type Ia supernovae emit nuclear γ- ray lines, from the 56Ni → 56Co → 56Fe radioactive decay. The energy released in these decays powers the SNIa UVOIR light curve at times after ~1 week, leading to an exponential decline. Importantly for Swift and Fermi, these decays are accompanied by γ-ray line emission, with distinct series of lines for both the 56Ni and 56Co decays, spanning 158 keV to 2.6 MeV. These lines are squarely within the Fermi/GBM energy range, and the 56Ni 158 keV line is detectable by Swift/BAT. The Galaxy is optically thin to γ-rays, so the supernova line flux will suffer negligible extinction. Both GBM and BAT have continuous and nearly all-sky coverage. Thus GBM and BAT are ideal Galactic SNIa monitors and early warning systems. We will illustrate expected GBM and BAT light curves and spectra, based on our model for SNIa γ-ray emission and transfer. We show that the supernova signal emerges as distinct from the GBM background within days after the explosion in the SN2014J shell model. Therefore, if a Galactic SNIa were to explode, there are two possibilities of confirming and sounding the alert: 1) Swift/BAT discovers the SNIa first and localizes it within arcminutes; 2) Fermi/GBM finds the SNIa first and localizes it to within ~1 degree, using the Earth occultation technique, followed up by BAT to localize it within arcminutes. After the alert of either BAT or GBM, Swift localizes it to take spectra in optical, UV, soft and hard X-rays simultaneously with both XRT and UVOT instruments.

Causal structure of analogue spacetimes

International Nuclear Information System (INIS)

Barcelo, Carlos; Liberati, Stefano; Sonego, Sebastiano; Visser, Matt

2004-01-01

The so-called 'analogue models of general relativity' provide a number of specific physical systems, well outside the traditional realm of general relativity, that nevertheless are well-described by the differential geometry of curved spacetime. Specifically, the propagation of perturbations in these condensed matter systems is described by 'effective metrics' that carry with them notions of 'causal structure' as determined by an exchange of quasi-particles. These quasi-particle-induced causal structures serve as specific examples of what can be done in the presence of a Lorentzian metric without having recourse to the Einstein equations of general relativity. (After all, the underlying analogue model is governed by its own specific physics, not necessarily by the Einstein equations.) In this paper we take a careful look at what can be said about the causal structure of analogue spacetimes, focusing on those containing quasi-particle horizons, both with a view to seeing what is different from standard general relativity, and what the similarities might be. For definiteness, and because the physics is particularly simple to understand, we will phrase much of the discussion in terms of acoustic disturbances in moving fluids, where the underlying physics is ordinary fluid mechanics, governed by the equations of traditional hydrodynamics, and the relevant quasi-particles are the phonons. It must however be emphasized that this choice of example is only for the sake of pedagogical simplicity and that our considerations apply generically to wide classes of analogue spacetimes

Natural analogues and radionuclide transport model validation

International Nuclear Information System (INIS)

Lever, D.A.

1987-08-01

In this paper, some possible roles for natural analogues are discussed from the point of view of those involved with the development of mathematical models for radionuclide transport and with the use of these models in repository safety assessments. The characteristic features of a safety assessment are outlined in order to address the questions of where natural analogues can be used to improve our understanding of the processes involved and where they can assist in validating the models that are used. Natural analogues have the potential to provide useful information about some critical processes, especially long-term chemical processes and migration rates. There is likely to be considerable uncertainty and ambiguity associated with the interpretation of natural analogues, and thus it is their general features which should be emphasized, and models with appropriate levels of sophistication should be used. Experience gained in modelling the Koongarra uranium deposit in northern Australia is drawn upon. (author)

The Palmottu analogue project

International Nuclear Information System (INIS)

Ahonen, L.; Blomqvist, R.; Suksi, J.

1993-01-01

The report gives a summary of the results of investigations carried out in 1992 at the Palmottu natural analogue study site, which is a small U-Th mineralization in Nummi-Pusula, southwestern Finland. Additionally, the report includes several separate articles dealing with various aspects of the Palmottu Analogue Project: (1) deep groundwater flow, (2) interpretation of hydraulic connections, (3) characterization of groundwater colloids, (4) uranium mineral-groundwater equilibrium, (5) water-rock interaction and (6) modelling of in situ matrix diffusion. The Palmottu Analogue Project aims at a more profound understanding of radionuclide transport processes in fractured crystalline bedrock. The essential factors controlling transport are groundwater flow and interaction between water and rock. Accordingly, the study includes (1) structural interpretations partly based on geophysical measurements, (2) hydrological studies including hydraulic drill-hole measurements, (3) flow modelling, (4) hydrogeochemical characterization of groundwater, uranium chemistry and colloid chemistry, (5) mineralogical studies, (6) geochemical interpretation and modelling, (7) studies of radionuclide mobilization and retardation including matrix diffusion, and (8) modelling of uranium series data. Palaeohydrogeological aspects, due to the anticipated future glaciation of the Fennoscandian Shield, are of special interest. Quaternary sediments are studied to gain information on post-glacial migration in the overburden. (orig.)

The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor.

Directory of Open Access Journals (Sweden)

Bryan L Roth

Full Text Available In this paper we determined the pharmacological profiles of novel ketamine and phencyclidine analogues currently used as 'designer drugs' and compared them to the parent substances via the resources of the National Institute of Mental Health Psychoactive Drug Screening Program. The ketamine analogues methoxetamine ((RS-2-(ethylamino-2-(3-methoxyphenylcyclohexanone and 3-MeO-PCE (N-ethyl-1-(3-methoxyphenylcyclohexanamine and the 3- and 4-methoxy analogues of phencyclidine, (1-[1-(3-methoxyphenylcyclohexyl]piperidine and 1-[1-(4-methoxyphenylcyclohexyl]piperidine, were all high affinity ligands for the PCP-site on the glutamate NMDA receptor. In addition methoxetamine and PCP and its analogues displayed appreciable affinities for the serotonin transporter, whilst the PCP analogues exhibited high affinities for sigma receptors. Antagonism of the NMDA receptor is thought to be the key pharmacological feature underlying the actions of dissociative anaesthetics. The novel ketamine and PCP analogues had significant affinities for the NMDA receptor in radioligand binding assays, which may explain their psychotomimetic effects in human users. Additional actions on other targets could be important for delineating side-effects.

The Swift Ultra-Violet/Optical Telescope

International Nuclear Information System (INIS)

Roming, Peter; Hunsberger, S.D.; Nousek, John; Mason, Keith

2001-01-01

The Ultra-Violet/Optical Telescope (UVOT) provides the Swift Gamma-Ray Burst Explorer with the capability of quickly detecting and characterizing the optical and ultraviolet properties of gamma ray burst counterparts. The UVOT design is based on the design of the Optical Monitor on XMM-Newton. It is a Ritchey-Chretien telescope with microchannel plate intensified charged-coupled devices (MICs) that deliver sub-arcsecond imaging. These MICs are photon-counting devices, capable of detecting low intensity signal levels. When flown above the atmosphere, the UVOT will have the sensitivity of a 4m ground based telescope, attaining a limiting magnitude of 24 for a 1000 second observation in the white light filter. A rotating filter wheel allows sensitive photometry in six bands spanning the UV and visible, which will provide photometric redshifts of objects in the 1-3.5z range. For bright counterparts, such as the 9th magnitude GRB990123, or for fainter objects down to 17th magnitude, two grisms provide low-resolution spectroscopy

Swift-heavy ion track electronics (SITE)

International Nuclear Information System (INIS)

Fink, D.; Chadderton, L.T.; Hoppe, K.; Fahrner, W.R.; Chandra, A.; Kiv, A.

2007-01-01

An overview about the state-of-art of the development of a new type of nanoelectronics based on swift-heavy ions is given. Polymeric as well as silicon-based substrates have been used, and both latent and etched ion tracks play a role. Nowadays the interest has shifted from simple scaling-down of capacitors, magnets, transformers, diodes, transistors, etc. towards new types of ion track-based structures hitherto unknown in electronics. These novel structures, denoted by the acronyms 'TEAMS' (tunable electrically anisotropic material on semiconductor) and 'TEMPOS' (tunable electronic material with pores in oxide on semiconductor), may exhibit properties of tunable resistors, capacitors, diodes, sensors and transistors. Their general current/voltage characteristics are outlined. As these structures are often influenced by ambient physical or chemical parameters they also act as sensors. A peculiarity of these structures is the occurrence of negative differential resistances (NDRs) which makes them feasible for applications in tunable flip-flops, amplifiers and oscillators

Swift-heavy ion track electronics (SITE)

Energy Technology Data Exchange (ETDEWEB)

Fink, D. [Hahn-Meitner-Institute Berlin, Glienicker Str. 100, D-14109 Berlin (Germany)]. E-mail: fink@hmi.de; Chadderton, L.T. [Institute of Advanced Studies, ANU Canberra, G.P.O. Box 4, ACT (Australia); Hoppe, K. [South Westfalia University of Applied Sciences, Hagen (Germany); Fahrner, W.R. [Chair of Electronic Devices, Inst. of Electrotechnique, Fernuniversitaet, Hagen (Germany); Chandra, A. [Department of Physics and Astrophysics, University of Delhi, Delhi 110 007 (India); Kiv, A. [Ben Gurion University of the Negev, Israel, P.O. Box 653, Beer-Sheva, 84105 (Israel)

2007-08-15

An overview about the state-of-art of the development of a new type of nanoelectronics based on swift-heavy ions is given. Polymeric as well as silicon-based substrates have been used, and both latent and etched ion tracks play a role. Nowadays the interest has shifted from simple scaling-down of capacitors, magnets, transformers, diodes, transistors, etc. towards new types of ion track-based structures hitherto unknown in electronics. These novel structures, denoted by the acronyms 'TEAMS' (tunable electrically anisotropic material on semiconductor) and 'TEMPOS' (tunable electronic material with pores in oxide on semiconductor), may exhibit properties of tunable resistors, capacitors, diodes, sensors and transistors. Their general current/voltage characteristics are outlined. As these structures are often influenced by ambient physical or chemical parameters they also act as sensors. A peculiarity of these structures is the occurrence of negative differential resistances (NDRs) which makes them feasible for applications in tunable flip-flops, amplifiers and oscillators.

Tuning the conductivity of vanadium dioxide films on silicon by swift heavy ion irradiation

Directory of Open Access Journals (Sweden)

H. Hofsäss

2011-09-01

Full Text Available We demonstrate the generation of a persistent conductivity increase in vanadium dioxide thin films grown on single crystal silicon by irradiation with 1 GeV 238U swift heavy ions at room temperature. VO2 undergoes a temperature driven metal-insulator-transition (MIT at 67 °C. After room temperature ion irradiation with high electronic energy loss of 50 keV/nm the conductivity of the films below the transition temperature is strongly increased proportional to the ion fluence of 5·109 U/cm2 and 1·1010 U/cm2. At high temperatures the conductivity decreases slightly. The ion irradiation slightly reduces the MIT temperature. This observed conductivity change is persistent and remains after heating the samples above the transition temperature and subsequent cooling. Low temperature measurements down to 15 K show no further MIT below room temperature. Although the conductivity increase after irradiation at such low fluences is due to single ion track effects, atomic force microscopy (AFM measurements do not show surface hillocks, which are characteristic for ion tracks in other materials. Conductive AFM gives no evidence for conducting ion tracks but rather suggests the existence of conducting regions around poorly conducting ion tracks, possible due to stress generation. Another explanation of the persistent conductivity change could be the ion-induced modification of a high resistivity interface layer formed during film growth between the vanadium dioxide film and the n-Silicon substrate. The swift heavy ions may generate conducting filaments through this layer, thus increasing the effective contact area. Swift heavy ion irradiation can thus be used to tune the conductivity of VO2 films on silicon substrates.

Swift-BAT: The First Year of Gamma-Ray Burst Detections

Science.gov (United States)

Krimm, Hans A.

2006-01-01

The Burst Alert Telescope (BAT) on the Swift has been detecting gamma-ray bursts (GRBs) since Dec. 17,2004 and automated burst alerts have been distributed since Feb. 14,2005. Since commissioning the BAT has triggered on more than 100 GRBs, nearly all of which have been followed up by the narrow-field instruments on Swift through automatic repointing, and by ground and other satellite telescopes after rapid notification. Within seconds of a trigger the BAT produces and relays to the ground a position good to three arc minutes and a four channel light curve. A full ten minutes of event data follows on subsequent ground station passes. The burst archive has allowed us to determine ensemble burst parameters such as fluence, peak flux and duration. An overview of the properties of BAT bursts and BAT'S performance as a burst monitor will be presented in this talk. BAT is a coded aperture imaging system with a wide (approx.2 sr) field of view consisting of a large coded mask located 1 m above a 5200 cm2 array of 32.768 CdZnTe detectors. All electronics and other hardware systems on the BAT have been operating well since commissioning and there is no sign of any degradation on orbit. The flight and ground software have proven similarly robust and allow the real time localization of all bursts and the rapid derivation of burst light curves, spectra and spectral fits on the ground.

Application of natural analogues in the Yucca Mountain project - overview

International Nuclear Information System (INIS)

Simmons, Ardyth M.

2003-01-01

The Natural Analogue Synthesis Report (NASR) [1] provides a compilation of information from analogues that test, corroborate, and add confidence to process models and model predictions pertinent to total system performance assessment (TSPA). The report updated previous work [2] with new literature examples and results of quantitative studies conducted by the Yucca Mountain Project (YMP). The intent of the natural analogue studies was to collect corroborative evidence from analogues to demonstrate greater understanding of processes expected to occur during postclosure of a proposed Yucca Mountain repository. Natural analogues, as used here, refer to either natural or anthropogenic systems in which processes similar to those expected to occur in a nuclear waste repository are thought to have occurred over long time periods (decades to millenia) and large spatial scales (up to tens of kilometers). In the past, the YMP has used analogues for testing and building confidence in conceptual and numerical process models in a number of ways. Yucca Mountain mineral alteration phases provided a self-analogue for postclosure alteration [3]. Thermodynamic parameters for silica minerals of the Wairakai, New Zealand geothermal field were added to databases used in geochemical modeling [4]. Scoping calculations of radionuclide transport using the Yucca Mountain TSPA numerical model were conducted for the Peqa Blanca site [5]. Eruption parameters from the Cerro Negro volcano, Nicaragua, were used to verify codes that model ash plume dispersion [6]. Analogues have also been used in supplemental science and performance analyses to provide multiple lines of evidence in support of both analyses and model reports (AMRs) [7]; in screening arguments for inclusion or exclusion of features, events, and processes (FEP)s in TSPAs; in the quantification of uncertainties [7]; in expert elicitations of volcanic and seismic hazards [8, 9] and in peer reviews [10]. Natural analogues may be applied

Synthesis and anticancer evaluation of spermatinamine analogues

KAUST Repository

Moosa, Basem

2016-02-04

Spermatinamine was isolated from an Australian marine sponge, Pseudoceratina sp. as an inhibitor of isoprenylcystiene carboxyl methyltransferase (Icmt), an attractive and novel anticancer target. Herein, we report the synthesis of spermatinamine analogues and their cytotoxic evaluation against three human cancer cell lines i.e. cervix adenocarcinoma (HeLa), breast adenocarcinoma (MCF-7), and prostate carcinoma (DU145). Analogues 12, 14 and 15 were found to be the most potent against one or more cell lines with the IC50 values in the range of 5 - 10 μM. The obtained results suggested that longer polyamine linker along with aromatic oxime substitution provided the most potent analogue compounds against cancer cell lines.

VizieR Online Data Catalog: Flux conversion factors for the Swift/UVOT filters (Brown+, 2016)

Science.gov (United States)

Brown, P. J.; Breeveld, A.; Roming, P. W. A.; Siegel, M.

2016-10-01

The conversion of observed magnitudes (or the actual observed photon or electron count rates) to a flux density is one of the most fundamental calculations. The flux conversions factors for the six Swift/UVOT filters are tabulated in Table1. (1 data file).

Experimental aspects of S.H.I.C. (Swift Heavy Ion Channeling)

International Nuclear Information System (INIS)

Quere, Y.; Mory, J.; Castro Faria, N.V. de; Chevallier, M.; Gaillard, M.J.; Genre, R.; Farizon-Mazuy, B.; Poizat, J.C.; Remillieux, J.; Dural, J.; Toulemonde, M.; Hage-Ali, M.

1989-01-01

We have studied the behaviour of swift heavy ions, of initial charge Z 0 , transmitted in a crystal. More precisely we have measured, for various values of Z 0 , the mean stopping power experienced by the ions of exit charge Z, together with the charge distribution n(Z). In this short note, we describe briefly the instrumental set-up, and give two specific results which make it possible to appreciate the accuracy and sensitivity of the experiment

Supergiant Fast X-ray Transients with Swift: spectroscopic and temporal properties

OpenAIRE

Romano, P.; Mangano, V.; Ducci, L.; Esposito, P.; Farinelli, R.; Ceccobello, C.; Vercellone, S.; Burrows, D. N.; Kennea, J. A.; Krimm, H. A.; Gehrels, N.

2012-01-01

Supergiant fast X-ray transients (SFXTs) are a class of high-mass X-ray binaries with possible counterparts in the high energy gamma rays. The Swift SFXT Project has conducted a systematic investigation of the properties of SFTXs on timescales ranging from minutes to years and in several intensity states (from bright flares, to intermediate intensity states, and down to almost quiescence). We also performed broad-band spectroscopy of outbursts, and intensity-selected spectroscopy outside of o...

Positron lifetime and Doppler broadening study of defects created by swift ion irradiation in sapphire

International Nuclear Information System (INIS)

Liszkay, L.; Gordo, P.M.; Lima, A. de; Havancsak, K.; Skuratov, V.A.; Kajcsos, Z.

2004-01-01

Swift ions create a defect profile penetrating deep into a solid compared to the sampling range of typical slow positron beams, which may consequently study a homogeneous zone of defected materials. To investigate the defect population created by energetic ions, we studied α-Al 2 O 3 single crystals irradiated with swift Kr ions by using conventional and pulsed positron beams. Samples irradiated with krypton at 245 MeV energy in a wide fluence range show nearly saturated positron trapping above 5 x 10 10 ions cm -2 fluence, indicating the creation of monovacancies in high concentration. At 1 x 10 14 ions cm -2 irradiation a 500 ps long lifetime component appears, showing the creation of larger voids. This threshold corresponds well to the onset of the overlap of the damage zones after Bi ion irradiation along the ion trajectories observed with microscopic methods. (orig.)

Conformationally restrained aromatic analogues of fosmidomycin and FR900098.

Science.gov (United States)

Kurz, Thomas; Schlüter, Katrin; Pein, Miriam; Behrendt, Christoph; Bergmann, Bärbel; Walter, Rolf D

2007-07-01

The synthesis and in-vitro antimalarial activity of conformationally restrained bis(pivaloyloxymethyl) ester analogues of the natural product fosmidomycin is presented. In contrast to alpha-aryl-substituted analogues, conformationally restrained aromatic analogues exhibit only moderate in-vitro antimalarial activity against the chloroquine-sensitive strain 3D7 of Plasmodium falciparum. The most active derivative displays an IC(50) value of 47 microM.

Further X-ray observations of Nova Del 2013 with Swift

Science.gov (United States)

Nelson, T.; Mukai, K.; Chomiuk, L.; Sokoloski, J.; Weston, J.; Zheng, Y.; Rupen, M.; Mioduszewski, A.; Linford, J.; Finzell, T.

2013-08-01

We observed Nova Del 2013 (see CBET #3628) with the Swift satellite on 2013-08-18, four days after discovery (see also ATEL #5283). The exposures were carried out between 0.0 and 15.7 UT, and are therefore coincident with the first appearance of gamma-ray emission from this nova as seen with the Fermi-LAT (ATEL #5302). The XRT instrument was operated in Window Timing (WT) in order to mitigate the impact of optical loading on the CCD, and the total exposure time was 4522s.

Downscaling of surface moisture flux and precipitation in the Ebro Valley (Spain using analogues and analogues followed by random forests and multiple linear regression

Directory of Open Access Journals (Sweden)

G. Ibarra-Berastegi

2011-06-01

Full Text Available In this paper, reanalysis fields from the ECMWF have been statistically downscaled to predict from large-scale atmospheric fields, surface moisture flux and daily precipitation at two observatories (Zaragoza and Tortosa, Ebro Valley, Spain during the 1961–2001 period. Three types of downscaling models have been built: (i analogues, (ii analogues followed by random forests and (iii analogues followed by multiple linear regression. The inputs consist of data (predictor fields taken from the ERA-40 reanalysis. The predicted fields are precipitation and surface moisture flux as measured at the two observatories. With the aim to reduce the dimensionality of the problem, the ERA-40 fields have been decomposed using empirical orthogonal functions. Available daily data has been divided into two parts: a training period used to find a group of about 300 analogues to build the downscaling model (1961–1996 and a test period (1997–2001, where models' performance has been assessed using independent data. In the case of surface moisture flux, the models based on analogues followed by random forests do not clearly outperform those built on analogues plus multiple linear regression, while simple averages calculated from the nearest analogues found in the training period, yielded only slightly worse results. In the case of precipitation, the three types of model performed equally. These results suggest that most of the models' downscaling capabilities can be attributed to the analogues-calculation stage.

Swift Burst Alert Telescope (BAT) Instrument Response

International Nuclear Information System (INIS)

Parsons, A.; Barthelmy, S.; Cummings, J.; Gehrels, N.; Hullinger, D.; Krimm, H.; Markwardt, C.; Tueller, J.; Fenimore, E.; Palmer, D.; Sato, G.; Takahashi, T.; Nakazawa, K.; Okada, Y.; Takahashi, H.; Suzuki, M.; Tashiro, M.

2004-01-01

The Burst Alert Telescope (BAT), a large coded aperture instrument with a wide field-of-view (FOV), provides the gamma-ray burst triggers and locations for the Swift Gamma-Ray Burst Explorer. In addition to providing this imaging information, BAT will perform a 15 keV - 150 keV all-sky hard x-ray survey based on the serendipitous pointings resulting from the study of gamma-ray bursts, and will also monitor the sky for transient hard x-ray sources. For BAT to provide spectral and photometric information for the gamma-ray bursts, the transient sources and the all-sky survey, the BAT instrument response must be determined to an increasingly greater accuracy. This paper describes the spectral models and the ground calibration experiments used to determine the BAT response to an accuracy suitable for gamma-ray burst studies

U.S. Nuclear Regulatory Commission natural analogue research program

International Nuclear Information System (INIS)

Kovach, L.A.; Ott, W.R.

1995-01-01

This article describes the natural analogue research program of the U.S. Nuclear Regulatory Commission (US NRC). It contains information on the regulatory context and organizational structure of the high-level radioactive waste research program plan. It also includes information on the conditions and processes constraining selection of natural analogues, describes initiatives of the US NRC, and describes the role of analogues in the licensing process

Swift heavy ions induced surface modifications in Ag-polypyrrole composite films synthesized by an electrochemical route

International Nuclear Information System (INIS)

Kumar, Vijay; Ali, Yasir; Sharma, Kashma; Kumar, Vinod; Sonkawade, R.G.; Dhaliwal, A.S.; Swart, H.C.

2014-01-01

Highlights: • Two steps electrochemical synthesis for the fabrication of Ag-polypyrrole composite films. • Surface modifications by swift heavy ion beam. • SEM image shows the formation of craters and humps after irradiation. • Detailed structural analysis by Raman spectroscopy. - Abstract: The general aim of this work was to study the effects of swift heavy ions on the properties of electrochemically synthesized Ag-polypyrrole composite thin films. Initially, polypyrrole (PPy) films were electrochemically synthesized on indium tin oxide coated glass surfaces using a chronopotentiometery technique, at optimized process conditions. The prepared PPy films have functioned as working electrodes for the decoration of submicron Ag particles on the surface of the PPy films through a cyclicvoltammetry technique. Towards probing the effect of swift heavy ion irradiation on the structural and morphological properties, the composite films were subjected to a 40 MeV Li 3+ ion beam irradiation for various fluences (1 × 10 11 , 1 × 10 12 and 1 × 10 13 ions/cm 2 ). Comparative microstructural investigations were carried out after the different ion fluences using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy and micro-Raman spectroscopy techniques. Raman and SEM studies revealed that the structure of the films became disordered after irradiation. The SEM studies of irradiated composite films show significant changes in their surface morphologies. The surface was smoother at lower fluence but craters were observed at higher fluence

Swift heavy ions induced surface modifications in Ag-polypyrrole composite films synthesized by an electrochemical route

Energy Technology Data Exchange (ETDEWEB)

Kumar, Vijay, E-mail: vijays_phy@rediffmail.com [Department of Physics, University of the Free State, P.O. Box 339, Bloemfontein ZA 9300 (South Africa); Ali, Yasir [Department of Physics, Sant Longowal Institute of Engineering and Technology, Longowal, District Sangrur 148106, Punjab (India); Sharma, Kashma [Department of Physics, University of the Free State, P.O. Box 339, Bloemfontein ZA 9300 (South Africa); Department of Chemistry, Shoolini University of Biotechnology and Management Sciences, Solan 173212 (India); Kumar, Vinod [Department of Physics, University of the Free State, P.O. Box 339, Bloemfontein ZA 9300 (South Africa); Sonkawade, R.G. [Inter University Accelerator Center, Aruna Asif Ali Marg, New Delhi 110067 (India); Dhaliwal, A.S. [Department of Physics, Sant Longowal Institute of Engineering and Technology, Longowal, District Sangrur 148106, Punjab (India); Swart, H.C., E-mail: swarthc@ufs.ac.za [Department of Physics, University of the Free State, P.O. Box 339, Bloemfontein ZA 9300 (South Africa)

2014-03-15

Highlights: • Two steps electrochemical synthesis for the fabrication of Ag-polypyrrole composite films. • Surface modifications by swift heavy ion beam. • SEM image shows the formation of craters and humps after irradiation. • Detailed structural analysis by Raman spectroscopy. - Abstract: The general aim of this work was to study the effects of swift heavy ions on the properties of electrochemically synthesized Ag-polypyrrole composite thin films. Initially, polypyrrole (PPy) films were electrochemically synthesized on indium tin oxide coated glass surfaces using a chronopotentiometery technique, at optimized process conditions. The prepared PPy films have functioned as working electrodes for the decoration of submicron Ag particles on the surface of the PPy films through a cyclicvoltammetry technique. Towards probing the effect of swift heavy ion irradiation on the structural and morphological properties, the composite films were subjected to a 40 MeV Li{sup 3+} ion beam irradiation for various fluences (1 × 10{sup 11}, 1 × 10{sup 12} and 1 × 10{sup 13} ions/cm{sup 2}). Comparative microstructural investigations were carried out after the different ion fluences using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy and micro-Raman spectroscopy techniques. Raman and SEM studies revealed that the structure of the films became disordered after irradiation. The SEM studies of irradiated composite films show significant changes in their surface morphologies. The surface was smoother at lower fluence but craters were observed at higher fluence.

FERMI/LAT OBSERVATIONS OF SWIFT/BAT SEYFERT GALAXIES: ON THE CONTRIBUTION OF RADIO-QUIET ACTIVE GALACTIC NUCLEI TO THE EXTRAGALACTIC γ-RAY BACKGROUND

International Nuclear Information System (INIS)

Teng, Stacy H.; Mushotzky, Richard F.; Reynolds, Christopher S.; Sambruna, Rita M.; Davis, David S.

2011-01-01

We present the analysis of 2.1 years of Fermi Large Area Telescope (LAT) data on 491 Seyfert galaxies detected by the Swift Burst Alert Telescope (BAT) survey. Only the two nearest objects, NGC 1068 and NGC 4945, which were identified in the Fermi first year catalog, are detected. Using Swift/BAT and radio 20 cm fluxes, we define a new radio-loudness parameter R X,BAT where radio-loud objects have log R X,BAT > –4.7. Based on this parameter, only radio-loud sources are detected by Fermi/LAT. An upper limit to the flux of the undetected sources is derived to be ∼2 × 10 –11 photons cm –2 s –1 , approximately seven times lower than the observed flux of NGC 1068. Assuming a median redshift of 0.031, this implies an upper limit to the γ-ray (1-100 GeV) luminosity of ∼ 41 erg s –1 . In addition, we identified 120 new Fermi/LAT sources near the Swift/BAT Seyfert galaxies with significant Fermi/LAT detections. A majority of these objects do not have Swift/BAT counterparts, but their possible optical counterparts include blazars, flat-spectrum radio quasars, and quasars.

Insulin analogues and cancer: a note of caution

Directory of Open Access Journals (Sweden)

Joseph A.M.J.L. eJanssen

2014-05-01

Full Text Available Abstract In view of the lifelong exposure and large patient populations involved, insulin analogues with an increased mitogenic effect in comparison to human insulin may potentially constitute a major health problem, since these analogues may possibly induce the growth of pre-existing neoplasms. At present, the available data suggest that insulin analogues are safe. In line with these findings, we observed that serum of diabetic patients treated with insulin analogues, compared to that of diabetic patients treated with human insulin, did not induce an increased phosphorylation of tyrosine residues of the insulin-like growth factor-I receptor (IGF-IR. However, the classical model of the IGF-IR signaling may be insufficient to explain (all mitogenic effects of insulin analogues since also non-canonical signaling pathways of the IGF-IR may play a major role in this respect. Although phosphorylation of tyrosine residues of the IGF-IR is generally considered to be the initial activation step within the intracellular IGF-IR signaling pathway, it has been found that cells undergo a signaling switch under hyperglycemic conditions. After this switch, a completely different mechanism is utilized to activate the mitogenic (mitogen-activated protein kinase (MAPK pathways of the IGF-IR that is independent from tyrosine phosphorylation of the IGF-IR. At present it is unknown whether activation of this alternative intracellular pathway of the IGF-IR occurs during hyperglycemia in vivo and whether it is stronger in patients treated with (some insulin analogues than in patients treated with human insulin. In addition, it is unknown whether the insulin receptors (IRs also undergo a signaling switch during hyperglycemia. This should be investigated in future studies. Finally, relative overexpression of IR isoform A (IR-A in (pre cancer tissues may play a key role in the development and progression of human cancers during treatment with insulin (analogues. Further

Characterisation of insulin analogues therapeutically available to patients

KAUST Repository

Adams, Gary G.

2018-03-29

The structure and function of clinical dosage insulin and its analogues were assessed. This included \\'native insulins\\' (human recombinant, bovine, porcine), \\'fast-acting analogues\\' (aspart, glulisine, lispro) and \\'slow-acting analogues\\' (glargine, detemir, degludec). Analytical ultracentrifugation, both sedimentation velocity and equilibrium experiments, were employed to yield distributions of both molar mass and sedimentation coefficient of all nine insulins. Size exclusion chromatography, coupled to multi-angle light scattering, was also used to explore the function of these analogues. On ultracentrifugation analysis, the insulins under investigation were found to be in numerous conformational states, however the majority of insulins were present in a primarily hexameric conformation. This was true for all native insulins and two fast-acting analogues. However, glargine was present as a dimer, detemir was a multi-hexameric system, degludec was a dodecamer (di-hexamer) and glulisine was present as a dimer-hexamer-dihexamer system. However, size-exclusion chromatography showed that the two hexameric fast-acting analogues (aspart and lispro) dissociated into monomers and dimers due to the lack of zinc in the mobile phase. This comprehensive study is the first time all nine insulins have been characterised in this way, the first time that insulin detemir have been studied using analytical ultracentrifugation and the first time that insulins aspart and glulisine have been studied using sedimentation equilibrium. The structure and function of these clinically administered insulins is of critical importance and this research adds novel data to an otherwise complex functional physiological protein.

Fungal growth inhibitory properties of new phytosphingolipid analogues.

Science.gov (United States)

Mormeneo, D; Manresa, A; Casas, J; Llebaria, A; Delgado, A

2008-04-01

To study the growth inhibitory properties of a series of phytosphingosine (PHS) and phytoceramide (PHC) analogues. A panel of two yeast (Candida albicans and Saccharomyces cerevisiae) and six moulds (Aspergillus repens, Aspergillus niger, Penicillium chrysogenum, Cladosporium cladosporioides, Arthroderma uncinatum and Penicillium funiculosum) has been used in this study. A series of new PHS and PHC analogues differing at the sphingoid backbone and the functional group at C1 position were synthesized. Among PHS analogues, 1-azido derivative 1c, bearing the natural D-ribo stereochemistry, showed a promising growth inhibitory profile. Among PHC analogues, compound 12, with a bulky N-pivaloyl group and a Z double bond at C3 position of the sphingoid chain, was the most active growth inhibitor. Minimal inhibitory concentration values were in the range of 23-48 micromol l(-1) for 1c and 44-87 micromol l(-1) for 12. Only scattered data on the antifungal activity of phytosphingolipids have been reported in the literature. This is the first time that a series of analogues of this kind are tested and compared to discern their structural requirements for antifungal activity.

Pentalum SpiDAR Deployment at SWiFT FY17.

Energy Technology Data Exchange (ETDEWEB)

Westergaard, Carsten [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Pol, Suhas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Pereira, Tassia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Castillo, Ricardo [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-12-01

The Texas Tech University ( TTU ) research group is actively studying the wake development of wind turbines, as part of developing innovative wake control strategies to improve the performance of wind farms. Recently, the team received a set of five new gro und lidars to perform field measurements at the Sandia National Laboratories SWiFT site. This document describes tests details including configurations, timeframe, hardware, and the required collaboration from the Sandia team. This test plan will facili tate the coordination between both TTU and the Sandia team in terms of site accessibility, staff training, and data sharing to meet the specific objectives of the tests.

Effect of acute pesticide exposure on bee spatial working memory using an analogue of the radial-arm maze

Science.gov (United States)

Samuelson, Elizabeth E. W.; Chen-Wishart, Zachary P.; Gill, Richard J.; Leadbeater, Ellouise

2016-12-01

Pesticides, including neonicotinoids, typically target pest insects by being neurotoxic. Inadvertent exposure to foraging insect pollinators is usually sub-lethal, but may affect cognition. One cognitive trait, spatial working memory, may be important in avoiding previously-visited flowers and other spatial tasks such as navigation. To test this, we investigated the effect of acute thiamethoxam exposure on spatial working memory in the bumblebee Bombus terrestris, using an adaptation of the radial-arm maze (RAM). We first demonstrated that bumblebees use spatial working memory to solve the RAM by showing that untreated bees performed significantly better than would be expected if choices were random or governed by stereotyped visitation rules. We then exposed bees to either a high sub-lethal positive control thiamethoxam dose (2.5 ng-1 bee), or one of two low doses (0.377 or 0.091 ng-1) based on estimated field-realistic exposure. The high dose caused bees to make more and earlier spatial memory errors and take longer to complete the task than unexposed bees. For the low doses, the negative effects were smaller but statistically significant, and dependent on bee size. The spatial working memory impairment shown here has the potential to harm bees exposed to thiamethoxam, through possible impacts on foraging efficiency or homing.

CO2 Capture with Enzyme Synthetic Analogue

Energy Technology Data Exchange (ETDEWEB)

Cordatos, Harry

2010-11-08

Overview of an ongoing, 2 year research project partially funded by APRA-E to create a novel, synthetic analogue of carbonic anhydrase and incorporate it into a membrane for removal of CO2 from flue gas in coal power plants. Mechanism background, preliminary feasibility study results, molecular modeling of analogue-CO2 interaction, and program timeline are provided.

Insulin analogues with improved absorption characteristics.

Science.gov (United States)

Brange, J; Hansen, J F; Langkjaer, L; Markussen, J; Ribel, U; Sørensen, A R

1992-01-01

The insulin preparations available today are not ideal for therapy as s.c. injection does not provide a physiological insulin profile. With the aim to improve the absorption properties recombinant DNA technology has been utilized to design novel insulin molecules with changed physico-chemical characteristics and hence altered subcutaneous absorption kinetics. Soluble, long-acting human insulin analogues in which the isoelectric point has been increased from 5.4 to approx. 7 are absorbed very slowly, providing a more constant basal insulin delivery with lower day-to-day variation than present protracted preparations. In addition they have better storage stability. Rapid-acting human insulin analogues with largely reduced self-association are absorbed substantially faster from subcutaneous tissue than current regular insulin and thus are better suited for bolus injection. The absorption kinetics of these analogues have been able to explain the mechanism behind the dose effect on insulin absorption rate.

A SWIFT Method for Handing Off Obstetrical Patients on the Labor Floor.

Science.gov (United States)

Sheen, Jean-Ju; Reimers, Laura; Govindappagari, Shravya; Ngai, Ivan M; Garretto, Diana; Donepudi, Roopali; Tropper, Pamela; Goffman, Dena; Dayal, Ashlesha K; Bernstein, Peter S

2017-07-06

The aim of this study was to improve patient handoffs on the labor floor. A prospective cohort study of obstetrics residents at Montefiore Medical Center was performed between 2012 and 2014. Labor-floor handoffs were recorded before and after didactic sessions as well as after installation of whiteboards formatted with the mnemonic SWIFT (Subject, Why?, Issues, Fetus, Tasks). Handoff transcripts were evaluated by obstetricians blinded to timing and speaker identity. An intraclass correlation coefficient accounted for evaluator differences. Data analysis was by ordinal logistic regression, the generalized estimating equations method (correlated data), and Bonferroni adjustment (multiple comparisons). Forty-five handoffs were evaluated (15 each predidactics, postdidactics, and postwhiteboard revision). Higher completeness scores over time were noted for admission reason, labor concerns, and task list (not statistically significant). Comprehensive score increases prelecture to postwhiteboard were seen in handoff clarity (2.81 versus 2.91) and overall quality (2.77 versus 2.81) (not statistically significant). A subanalysis of four residents who gave multiple handoffs over different periods revealed few significant changes over time. Greater interevaluator consistency was noted with more objective elements. The mnemonic SWIFT, with formalized curricula for obstetrical resident training focusing on new learners and increased faculty involvement and reinforcement, may result in improvement of handoffs on the labor floor.

NUSTAR, SWIFT, and GROND Observations of the Flaring MEV Blazar PMN J0641-0320

DEFF Research Database (Denmark)

Ajello, M.; Ghisellini, G.; Paliya, V. S.

2016-01-01

Area Telescope and subsequent follow-up observations with NuSTAR, Swift, and GROND of a new member of the MeV blazar family: PMN J0641-0320. Our optical spectroscopy provides confirmation that this is a flat-spectrum radio quasar located at a redshift of z = 1.196. Its very hard NuSTAR spectrum (power...

Correlative Spectral Analysis of Gamma-Ray Bursts using Swift-BAT and GLAST-GBM

International Nuclear Information System (INIS)

Stamatikos, Michael; Sakamoto, Taka; Band, David L.

2008-01-01

We discuss the preliminary results of spectral analysis simulations involving anticipated correlated multi-wavelength observations of gamma-ray bursts (GRBs) using Swift's Burst Alert Telescope (BAT) and the Gamma-Ray Large Area Space Telescope's (GLAST) Burst Monitor (GLAST-GBM), resulting in joint spectral fits, including characteristic photon energy (E peak ) values, for a conservative annual estimate of ∼30 GRBs. The addition of BAT's spectral response will (i) complement in-orbit calibration efforts of GBM's detector response matrices, (ii) augment GLAST's low energy sensitivity by increasing the ∼20-100 keV effective area, (iii) facilitate ground-based follow-up efforts of GLAST GRBs by increasing GBM's source localization precision, and (iv) help identify a subset of non-triggered GRBs discovered via off-line GBM data analysis. Such multi-wavelength correlative analyses, which have been demonstrated by successful joint-spectral fits of Swift-BAT GRBs with other higher energy detectors such as Konus-WIND and Suzaku-WAM, would enable the study of broad-band spectral and temporal evolution of prompt GRB emission over three energy decades, thus potentially increasing science return without placing additional demands upon mission resources throughout their contemporaneous orbital tenure over the next decade.

Correlative Spectral Analysis of Gamma-Ray Bursts using Swift-BAT and GLAST-GBM

International Nuclear Information System (INIS)

Stamatikos, Michael; Sakamoto, Takanori; Band, David L.

2008-01-01

We discuss the preliminary results of spectral analysis simulations involving anticipated correlated multi-wavelength observations of gamma-ray bursts (GRBs) using Swift's Burst Alert Telescope (BAT) and the Gamma-Ray Large Area Space Telescope's (GLAST) Burst Monitor (GLAST-GBM), resulting in joint spectral fits, including characteristic photon energy (E peak ) values, for a conservative annual estimate of ∼30 GRBs. The addition of BAT/s spectral response will (i) complement in-orbit calibration efforts of GBM's detector response matrices, (ii) augment GLAST's low energy sensitivity by increasing the ∼20-100 keV effective area, (iii) facilitate ground-based follow-up efforts of GLAST GRBs by increasing GBM's source localization precision, and (iv) help identify a subset of non-triggered GRBs discovered via off-line GBM data analysis. Such multi-wavelength correlative analyses, which have been demonstrated by successful joint-spectral fits of Swift-BAT GRBs with other higher energy detectors such as Konus-WIND and Suzaku-WAM, would enable the study of broad-band spectral and temporal evolution of prompt GRB emission over three energy decades, thus potentially increasing science return without placing additional demands upon mission resources throughout their contemporaneous orbital tenure over the next decade

Iron K and Compton hump reverberation in SWIFT J2127.4+5654 and NGC 1365 revealed by NuSTAR and XMM–Newton

DEFF Research Database (Denmark)

Kara, E.; Zoghbi, A.; Marinucci, A.

2015-01-01

In the past five years, a flurry of X-ray reverberation lag measurements of accreting supermassive black holes have been made using the XMM–Newton telescope in the 0.3–10 keV energy range. In this work, we use the NuSTAR (Nuclear Spectroscopic Telescope Array) telescope to extend the lag analysis...... up to higher energies for two Seyfert galaxies, SWIFT J2127.4+5654 and NGC 1365. X-ray reverberation lags are due to the light travel time delays between the direct continuum emission and the reprocessed emission from the inner radii of an ionized accretion disc. XMM–Newton has been particularly...... evidence for Compton reflection, known as the Compton ‘hump’. The XMM–Newton data show Fe K lags in both SWIFT J2127.4+5654 and NGC 1365. The NuSTAR data provide independent confirmation of these Fe K lags, and also show evidence for the corresponding Compton hump lags, especially in SWIFT J2127...

Natural analogue working group

International Nuclear Information System (INIS)

Come, B.; Chapman, N.

1986-01-01

A Natural Analogue Working Group was established by the Commission of the European Communities in 1985. The purpose of this group is to bring together modellers with earth scientists and others, so that maximum benefit can be obtained from natural analogue studies with a view to safe geological disposal of radioactive waste. The first meeting of this group was held in Brussels from November 5 to 7, 1985. The discussions mainly concerned the identification of the modellers' needs and of the earth scientists' capacity to provide for them. Following the debates, a written statement was produced by the Group; this document forms the core of the present Report. Notes and outlines of many of the presentations made are grouped in four appendixes. The valuable contribution of all those involved in the meeting is gratefully acknowledged

Analogues of uracil nucleosides with intrinsic fluorescence (NIF-analogues): synthesis and photophysical properties.

Science.gov (United States)

Segal, Meirav; Fischer, Bilha

2012-02-28

Uridine cannot be utilized as fluorescent probe due to its extremely low quantum yield. For improving the uracil fluorescence characteristics we extended the natural chromophore at the C5 position by coupling substituted aromatic rings directly or via an alkenyl or alkynyl linker to create fluorophores. Extension of the uracil base was achieved by treating 5-I-uridine with the appropriate boronic acid under the Suzuki coupling conditions. Analogues containing an alkynyl linker were obtained from 5-I-uridine and the suitable boronic acid in a Sonogashira coupling reaction. The uracil fluorescent analogues proposed here were designed to satisfy the following requirements: a minimal chemical modification at a position not involved in base-pairing, resulting in relatively long absorption and emission wavelengths and high quantum yield. 5-((4-Methoxy-phenyl)-trans-vinyl)-2'-deoxy-uridine, 6b, was found to be a promising fluorescent probe. Probe 6b exhibits a quantum yield that is 3000-fold larger than that of the natural chromophore (Φ 0.12), maximum emission (478 nm) which is 170 nm red shifted as compared to uridine, and a Stokes shift of 143 nm. In addition, since probe 6b adopts the anti conformation and S sugar puckering favored by B-DNA, it makes a promising nucleoside analogue to be incorporated in an oligonucleotide probe for detection of genetic material.

The diverse broad-band light-curves of Swift GRBs reproduced with the cannonball model

CERN Document Server

Dado, Shlomo; De Rújula, A

2009-01-01

Two radiation mechanisms, inverse Compton scattering (ICS) and synchrotron radiation (SR), suffice within the cannonball (CB) model of long gamma ray bursts (LGRBs) and X-ray flashes (XRFs) to provide a very simple and accurate description of their observed prompt emission and afterglows. Simple as they are, the two mechanisms and the burst environment generate the rich structure of the light curves at all frequencies and times. This is demonstrated for 33 selected Swift LGRBs and XRFs, which are well sampled from early time until late time and well represent the entire diversity of the broad band light curves of Swift LGRBs and XRFs. Their prompt gamma-ray and X-ray emission is dominated by ICS of glory light. During their fast decline phase, ICS is taken over by SR which dominates their broad band afterglow. The pulse shape and spectral evolution of the gamma-ray peaks and the early-time X-ray flares, and even the delayed optical `humps' in XRFs, are correctly predicted. The canonical and non-canonical X-ra...

In-situ investigations of surface modifications by swift heavy ions

International Nuclear Information System (INIS)

Bolse, W.; Sankarakumar, A.; Ferhati, R.; Garmatter, D.; Haag, M.; Dautel, K.; Asdi, M.; Srivastava, N.; Widmann, B.; Bauer, M.

2014-01-01

We are running a High Resolution Scanning Electron Microscope in the beam line of the UNILAC ion accelerator at the GSI Helmholtz Centre for Heavy Ion Research in Danustadt, Germany, which has recently been extended also with an EDX-system and two micro-manipulators. This instrument allows us to in-situ investigate the structural and compositional development of individual objects and structures in the μm- and nm-range under swift heavy ion bombardment, from the very first ion impact up to high fluences of the order of several 10 15 /cm 2 . The sample under investigation is irradiated in small fluence steps and in between SEM-images (and EDX-scans) of one and the same surface area are taken. The irradiation can be carried out at any incidence angle between 0° and 90° and also under stepwise or continuous azimuthal rotation of the sample. The micro-manipulator system allows us to perform additional analysis like electrical and mechanical characterization as well as substrate-free EDX at sub-μm objects. We are now also able to irradiate almost free standing sub-μm structures (pasted on a nanoscale tip or held in micro-tweezers). In this report an overview over this unique instrument and its capabilities and advantages will be given, illustrated by the results of our recent in-situ studies on ion induced modification of thin films (dewetting and self-organisation) and on shaping of sub-μm objects with swift heavy ions (by taking advantage of ion sputtering, ion hammering and ion induced visco-elastic flow). (author)

De Swift a Sterne: reflexões sobre o humor britânico na obra de Machado de Assis = From Swift to Sterne: reflections on British humour in the works of Machado de Assis

Directory of Open Access Journals (Sweden)

William Valentine Redmond

2011-01-01

Full Text Available Os humoristas britânicos, especialmente Swift e Sterne são tradicionalmente vistos como escritores que influenciaram a obra de Machado de Assis. Entretanto, foi o crítico Eugenio Gomes que provou, com precisão, a sutileza e o bom gosto que Machado obteve dessa influência. Em uma abordagem contemporânea, torna-se interessante questionar essa idéia de influência e examinar, à luz da intertextualidade, esse contato do humor entre as obras de Machado e as dessas duas grandes figuras da Literatura na Língua Inglesa.The British humourists, especially Swift and Sterne are traditionallyseen as writers who influenced Machado de Assis’ works. However it was the critic Eugenio Gomes who showed with precision the sublety and excellent taste of Machado obtained through this influence. With our contemporary approaches, it becomes interesting to question the idea of influence and examine in the light of intertextuality this contact of humour between the works of Machado and those of these two great figures of Literature in the English Language.

A Low-cost Multi-channel Analogue Signal Generator

CERN Document Server

Müller, F; The ATLAS collaboration; Shen, W; Stamen, R

2009-01-01

A scalable multi-channel analogue signal generator is presented. It uses a commercial low-cost graphics card with multiple outputs in a standard PC as signal source. Each color signal serves as independent channel to generate an analogue signal. A custom-built external PCB was developed to adjust the graphics card output voltage levels for a specific task, which needed differential signals. The system furthermore comprises a software package to program the signal shape. The signal generator was successfully used as independent test bed for the ATLAS Level-1 Trigger Pre-Processor, providing up to 16 analogue signals.

Effect of swift heavy ion irradiation on surface resistance of DyBa 2

Indian Academy of Sciences (India)

We report the observation of a pronounced peak in surface resistance at microwave frequencies of 4.88 GHz and 9.55 GHz and its disappearance after irradiation with swift ions in laser ablated DyBa2Cu3O7- (DBCO) thin films. The measurements were carried out in zero field as well as in the presence of magnetic fields ...

The optical counterpart of the bright X-ray transient Swift J1745-26

NARCIS (Netherlands)

Muñoz-Darias, T.; de Ugarte Postigo, A.; Russell, D.M.; Guziy, S.; Gorosabel, J.; Casares, J.; Armas Padilla, M.; Charles, P.A.; Fender, R.P.; Belloni, T.M.; Lewis, F.; Motta, S.; Castro-Tirado, A.; Mundell, C.G.; Sánchez-Ramirez, R.; Thöne, C.C.

2013-01-01

We present a 30-day monitoring campaign of the optical counterpart of the bright X-ray transient Swift J1745−26, starting only 19 min after the discovery of the source. We observe the system peaking at i′ ∼ 17.6 on day six (MJD 561 92) to then decay at a rate of ∼0.04 mag d−1. We show that the

On the Nature of the Hard X-Ray Sources SWIFT J1907.3-2050, IGR J12123-5802 and IGR J19552+0044

Science.gov (United States)

Bernardini, F.; deMartino, D; Mukai, K.; Falanga, M.; Andruchow, I.; Bonnet-Bidaud, J.-M.; Masetti, N.; GonzalezBuitrago, D. H.; Mouchet, M.; Tovmassian, G.

2014-01-01

The INTEGRAL and Swift hard X-ray surveys have identified a large number of new sources, among which many are proposed as Cataclysmic Variables (CVs). Here we present the first detailed study of three X-ray selected CVs, Swift J1907.3-2050, IGRJ12123-5802, and IGRJ19552+0044 based on XMM-Newton, Suzaku, Swift observations and ground based optical and archival nIR/IR data. Swift J1907.3-2050 is highly variable from hours to monthsyears at all wavelengths. No coherent X-ray pulses are detected but rather transient features. The X-ray spectrum reveals a multi-temperature optically thin plasma absorbed by complex neutral material and a soft black body component arising from a small area. These characteristics are remarkably similar to those observed in magnetic CVs. A supra-solar abundance of nitrogen could arise from nuclear processed material from the donor star. Swift J1907.3-2050 could be a peculiar magnetic CV with the second longest (20.82 h) binary period. IGRJ12123-5802 is variable in the X-rays on a timescale of approximately or greater than 7.6 h. No coherent pulsations are detected, but its spectral characteristics suggest that it could be a magnetic CV of the Intermediate Polar (IP) type. IGRJ19552+0044 shows two X-ray periods, approximately 1.38 h and approximately 1.69 h and a X-ray spectrum characterized by a multi-temperature plasma with little absorption.We derive a low accretion rate, consistent with a CV below the orbital period gap. Its peculiar nIR/IR spectrum suggests a contribution from cyclotron emission. It could either be a pre-polar or an IP with the lowest degree of asynchronism.

Swift adsorptive removal of Congo red from aqueous solution by K1.33Mn8O16 nanowires.

Science.gov (United States)

Wu, Junshu; Li, Hongyi; Wang, Jinshu; Li, Zhifei

2013-08-01

A swift and efficient approach to converting organic dye effluents into fresh water could be of substantial benefit. In this study, we presented facile hydrothermal synthesis of K1.33Mn8O16 nanowires in ammonium fluoride (NH4F) aqueous solution. The crystallization process of K1.33Mn8O16 nanowires was investigated. The as-obtained K1.33Mn8O16 nanowires were used for swift adsorptive removal of Congo red from aqueous solution without adjusting pH value at room temperature. Adsorption kinetic experimental data are well described by pseudo-second-order rate kinetic model, and the adsorption isotherm fits Langmuir isotherm model. The present investigation provides an efficient approach to designing and fabricating manganese-based nanomaterials for environmental remediation.

The effects of swift heavy ion irradiation on the structural properties of poly(lactide-co-glycolide)/clay nanocomposite

Energy Technology Data Exchange (ETDEWEB)

Kaur, Manpreet, E-mail: manpreet.kaur@abesit.in [ABES Institute of Technology,Ghaziabad, Uttar Pradesh (India); Singh, Surinder [Department of Physics, Guru Nanak Dev University, Amritsar (India); Mehta, Rajeev [Department of Chemical Engineering, Thapar University, Patiala (India)

2016-05-23

Radiation has been used as a processing technique to modify structural, chemical, physical and morphological properties of polymers and its nanocomposite and can thus be used as a method to control the rate of degradation. The swift heavy ions (SHI) irradiation effects on the structural properties of poly(lactide-co-glycolide) nanocomposites containing 5 wt% organo-montmorillonite (OMMT) clay by irradiating with 50 MeV Li{sup 3+} and 180 MeV Ag{sup 8+} ions has been studied at different fluences. The structural responses of PLGA nanocomposite under the influence of SHI were studied using Fourier transform infrared (FTIR) spectroscopy. The presence of clay and irradiation by swift heavy ions (SHI) brings out interesting changes in structural properties of nanocomposite.

Active Galaxy Host Properties from a New H I 21-cm Survey of the Swift BAT-detected AGN

Science.gov (United States)

Winter, Lisa M.; George, E. R.; Zauderer, B.; Darling, J.

2013-01-01

Many questions remain open on how central supermassive black holes and their host galaxies form and affect each other's evolution. In order to answer these questions, we need to understand the observational properties of a complete sample of active galaxies. To this end, we have been collecting and studying multi-wavelength spectroscopy of a unique sample of active galaxies selected in the very hard X-rays with the Swift Burst Alert Telescope. Here we present an analysis of the 21-cm H I spectra, which we observed with the 100-m Green Bank Telescope in 2012, for a sample of 95 Swift-detected AGN. With this complete sample, we show evidence for differences in the host cold gas mass content between obscured and unobscured AGN.

Synthesis of an Orthogonal Topological Analogue of Helicene

DEFF Research Database (Denmark)

Wixe, Torbjörn; Wallentin, Carl‐Johan; Johnson, Magnus T.

2013-01-01

The synthesis of an orthogonal topological pentamer analogue of helicene is presented. This analogue forms a tubular structure with its aromatic systems directed parallel to the axis of propagation, which creates a cavity with the potential to function as a host molecule. The synthetic strategy r...

Phosphorylation of inositol 1,4,5-trisphosphate analogues by 3-kinase and dephosphorylation of inositol 1,3,4,5-tetrakisphosphate analogues by 5-phosphatase

NARCIS (Netherlands)

Dijken, Peter van; Lammers, Aleida A.; Ozaki, Shoichiro; Potter, Barry V.L.; Erneux, Christophe; Haastert, Peter J.M. van

1994-01-01

A series of P-32-labeled D-myo-inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4,5)P-4] analogues was enzymically prepared from the corresponding D-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P-3] analogues using recombinant rat brain Ins(1,4,5)P-3 3-kinase and [gamma-P-32]ATP. Ins(1,4,5)P-3 analogues

On the robustness of entanglement in analogue gravity systems

International Nuclear Information System (INIS)

Bruschi, D E; Friis, N; Fuentes, I; Weinfurtner, S

2013-01-01

We investigate the possibility of generating quantum-correlated quasi-particles utilizing analogue gravity systems. The quantumness of these correlations is a key aspect of analogue gravity effects and their presence allows for a clear separation between classical and quantum analogue gravity effects. However, experiments in analogue systems, such as Bose–Einstein condensates (BECs) and shallow water waves, are always conducted at non-ideal conditions, in particular, one is dealing with dispersive media at non-zero temperatures. We analyse the influence of the initial temperature on the entanglement generation in analogue gravity phenomena. We lay out all the necessary steps to calculate the entanglement generated between quasi-particle modes and we analytically derive an upper bound on the maximal temperature at which given modes can still be entangled. We further investigate a mechanism to enhance the quantum correlations. As a particular example, we analyse the robustness of the entanglement creation against thermal noise in a sudden quench of an ideally homogeneous BEC, taking into account the super-sonic dispersion relations. (paper)

A preliminary feasibility study on natural analogue in Korea

Energy Technology Data Exchange (ETDEWEB)

Kim, Chun Soo; Bae, Dae Seok; Kim, Kyung Su; Koh, Yong Kwon; Park, Byung Yun

2000-03-01

Preliminary study on the assessment of natural analogue study in Korea for the deep geological disposal of high-level radioactive waste was carried out. The project on natural analogue study in other countries are introduced. The uranium-bearing deposit in Okcheon belt are summarized, which reported to be uranium-bearing minerals in order to assess to feasibility for natural analogue study in Korea. Among the uranium-bearing deposits, the Deokpyeong area, reported to be the highest reservoir and grade, are selected as the study site, and the elementary investigation, including survey of radioactivity and geochemistry are carried out. According to the investigation of surface environment, the radioactivity and uranium content in the surface water and shallow groundwater does not show any anormal values. However, the radioactivity is expected to be increased in depth and the groundwater reacted with uranium-bearing graphite formation shows high unanium content, indicating the potential possibility for natural analogue study in Korea. In future, if more detail study are performed, the assessment of natural analogue study in Korea are expected.

Analogue Signal Processing: Collected Papers 1994-95

DEFF Research Database (Denmark)

1996-01-01

This document is a collection of the papers presented at international conferences and in international journals by the analogue signal processing group of Electronics Institute, Technical University of Denmark, in 1994 and 1995.......This document is a collection of the papers presented at international conferences and in international journals by the analogue signal processing group of Electronics Institute, Technical University of Denmark, in 1994 and 1995....

Degradation of polyimide under irradiation with swift heavy ions

International Nuclear Information System (INIS)

Severin, D.; Ensinger, W.; Neumann, R.; Trautmann, C.; Walter, G.; Alig, I.; Dudkin, S.

2005-01-01

Stacks of polyimide foils were irradiated with different swift heavy ions (Ti, Mo, Au) of 11.1 MeV/nucleon energy and fluences between 1 x 10 10 and 2 x 10 12 ions/cm 2 . Beam-induced degradation of the imide group was analyzed by Fourier-transform infrared spectroscopy studying the absorption band at 725 cm -1 as a function of dose. In the UV-Vis spectral range, the absorption edge is shifted to larger wavelengths indicating carbonization. Such modifications are linked to the deposition of a critical dose of 2.7 MGy (Ti) and 1 MGy (Mo, Au). In addition, irradiation-induced changes of the electrical conductivity were studied by means of dielectric spectroscopy

THE 22 MONTH SWIFT-BAT ALL-SKY HARD X-RAY SURVEY

International Nuclear Information System (INIS)

Tueller, J.; Baumgartner, W. H.; Markwardt, C. B.; Skinner, G. K.; Mushotzky, R. F.; Barthelmy, S.; Cummings, J.; Gehrels, N.; Holland, S.; Ajello, M.; Beardmore, A.; Evans, P.; Godet, O.; Brandt, W. N.; Burrows, D.; Grupe, D.; Chincarini, G.; Campana, S.; Cusumano, G.; Fenimore, E.

2010-01-01

We present the catalog of sources detected in the first 22 months of data from the hard X-ray survey (14-195 keV) conducted with the Burst Alert Telescope (BAT) coded mask imager on the Swift satellite. The catalog contains 461 sources detected above the 4.8σ level with BAT. High angular resolution X-ray data for every source from Swift-XRT or archival data have allowed associations to be made with known counterparts in other wavelength bands for over 97% of the detections, including the discovery of ∼30 galaxies previously unknown as active galactic nuclei and several new Galactic sources. A total of 266 of the sources are associated with Seyfert galaxies (median redshift z ∼ 0.03) or blazars, with the majority of the remaining sources associated with X-ray binaries in our Galaxy. This ongoing survey is the first uniform all-sky hard X-ray survey since HEAO-1 in 1977. Since the publication of the nine-month BAT survey we have increased the number of energy channels from four to eight and have substantially increased the number of sources with accurate average spectra. The BAT 22 month catalog is the product of the most sensitive all-sky survey in the hard X-ray band, with a detection sensitivity (4.8σ) of 2.2 x 10 -11 erg cm -2 s -1 (1 mCrab) over most of the sky in the 14-195 keV band.

NuSTARand Swift observations of the very high state in GX 339-4: Weighing the black hole with X-rays

DEFF Research Database (Denmark)

Parker, M. L.; Tomsick, J. A.; Kennea, J. A.

2016-01-01

We present results from spectral fitting of the very high state of GX 339-4 with Nuclear Spectroscopic Telescope Array (NuSTAR) and Swift. We use relativistic reflection modeling to measure the spin of the black hole and inclination of the inner disk and find a spin of a = 0.95(-0.08)(+0.02) and ......We present results from spectral fitting of the very high state of GX 339-4 with Nuclear Spectroscopic Telescope Array (NuSTAR) and Swift. We use relativistic reflection modeling to measure the spin of the black hole and inclination of the inner disk and find a spin of a = 0...

A COMPLETE SAMPLE OF BRIGHT SWIFT LONG GAMMA-RAY BURSTS. I. SAMPLE PRESENTATION, LUMINOSITY FUNCTION AND EVOLUTION

International Nuclear Information System (INIS)

Salvaterra, R.; Campana, S.; Vergani, S. D.; Covino, S.; D'Avanzo, P.; Fugazza, D.; Ghirlanda, G.; Ghisellini, G.; Melandri, A.; Sbarufatti, B.; Tagliaferri, G.; Nava, L.; Flores, H.; Piranomonte, S.

2012-01-01

We present a carefully selected sub-sample of Swift long gamma-ray bursts (GRBs) that is complete in redshift. The sample is constructed by considering only bursts with favorable observing conditions for ground-based follow-up searches, which are bright in the 15-150 keV Swift/BAT band, i.e., with 1-s peak photon fluxes in excess to 2.6 photons s –1 cm –2 . The sample is composed of 58 bursts, 52 of them with redshift for a completeness level of 90%, while another two have a redshift constraint, reaching a completeness level of 95%. For only three bursts we have no constraint on the redshift. The high level of redshift completeness allows us for the first time to constrain the GRB luminosity function and its evolution with cosmic times in an unbiased way. We find that strong evolution in luminosity (δ l = 2.3 ± 0.6) or in density (δ d = 1.7 ± 0.5) is required in order to account for the observations. The derived redshift distributions in the two scenarios are consistent with each other, in spite of their different intrinsic redshift distributions. This calls for other indicators to distinguish among different evolution models. Complete samples are at the base of any population studies. In future works we will use this unique sample of Swift bright GRBs to study the properties of the population of long GRBs.

A COMPLETE SAMPLE OF BRIGHT SWIFT LONG GAMMA-RAY BURSTS. I. SAMPLE PRESENTATION, LUMINOSITY FUNCTION AND EVOLUTION

Energy Technology Data Exchange (ETDEWEB)

Salvaterra, R. [INAF, IASF Milano, via E. Bassini 15, I-20133 Milano (Italy); Campana, S.; Vergani, S. D.; Covino, S.; D' Avanzo, P.; Fugazza, D.; Ghirlanda, G.; Ghisellini, G.; Melandri, A.; Sbarufatti, B.; Tagliaferri, G. [INAF, Osservatorio Astronomico di Brera, via E. Bianchi 46, I-23807 Merate (Saint Lucia) (Italy); Nava, L. [SISSA, via Bonomea 265, I-34136 Trieste (Italy); Flores, H. [Laboratoire GEPI, Observatoire de Paris, CNRS-UMR8111, Univ. Paris-Diderot 5 place Jules Janssen, 92195 Meudon (France); Piranomonte, S., E-mail: ruben@lambrate.inaf.it [INAF, Osservatorio Astronomico di Roma, via Frascati 33, 00040 Monte Porzio Catone, Rome (Italy)

2012-04-10

We present a carefully selected sub-sample of Swift long gamma-ray bursts (GRBs) that is complete in redshift. The sample is constructed by considering only bursts with favorable observing conditions for ground-based follow-up searches, which are bright in the 15-150 keV Swift/BAT band, i.e., with 1-s peak photon fluxes in excess to 2.6 photons s{sup -1} cm{sup -2}. The sample is composed of 58 bursts, 52 of them with redshift for a completeness level of 90%, while another two have a redshift constraint, reaching a completeness level of 95%. For only three bursts we have no constraint on the redshift. The high level of redshift completeness allows us for the first time to constrain the GRB luminosity function and its evolution with cosmic times in an unbiased way. We find that strong evolution in luminosity ({delta}{sub l} = 2.3 {+-} 0.6) or in density ({delta}{sub d} = 1.7 {+-} 0.5) is required in order to account for the observations. The derived redshift distributions in the two scenarios are consistent with each other, in spite of their different intrinsic redshift distributions. This calls for other indicators to distinguish among different evolution models. Complete samples are at the base of any population studies. In future works we will use this unique sample of Swift bright GRBs to study the properties of the population of long GRBs.

The extrapolar SWIFT-model: Fast stratospheric ozone chemistry for global climate models

OpenAIRE

Kreyling, Daniel

2016-01-01

The goal of this PhD-thesis was the development of a fast yet accurate chemistry scheme for an interactive calculation of the extrapolar stratospheric ozone layer. The SWIFT-model is mainly intended for use in Global Climate Models (GCMs). For computing-time reasons GCMs often do not employ full stratospheric chemistry modules, but use prescribed ozone instead. This method does not consider the interaction between atmospheric dynamics and the ozone layer and can neither resolve the inter-annu...

A chemoselective and continuous synthesis of m-sulfamoylbenzamide analogues

Directory of Open Access Journals (Sweden)

Arno Verlee

2017-02-01

Full Text Available For the synthesis of m-sulfamoylbenzamide analogues, small molecules which are known for their bioactivity, a chemoselective procedure has been developed starting from m-(chlorosulfonylbenzoyl chloride. Although a chemoselective process in batch was already reported, a continuous-flow process reveals an increased selectivity at higher temperatures and without catalysts. In total, 15 analogues were synthesized, using similar conditions, with yields ranging between 65 and 99%. This is the first automated and chemoselective synthesis of m-sulfamoylbenzamide analogues.

On Using Current Steering Logic in Mixed Analogue-digital Circuits

DEFF Research Database (Denmark)

Lehmann, Torsten

1998-01-01

The authors investigate power supply noise in mixed analogue-digital circuits, arising from communication between the analogue and digital parts of the circuit. Current steering techniques and proper buffering are used to show which noise currents can be reduced and which cannot. In addition......, a high-swing current steering buffer for driving analogue switches or external digital signals is proposed....

UK Natural Analogue Coordinating Group: fourth annual report

International Nuclear Information System (INIS)

Read, D.; Hooker, P.J.

1992-01-01

HMIP has a research programme investigating some naturally radioactive sites as geochemical analogues of radionuclide migration. All of the analogue sites under investigation, both in the U.K. and overseas, are located where elevated uranium concentrations occur naturally. Coordination of the programme is achieved through the UK Natural Analogue Co-ordinating Group (NACG) which has met three times in this reporting period. The NACG is steered by the British Geological Survey. Its purpose is to ensure that the different research projects have an integrated function aimed at increasing our understanding of natural geochemical processes. Effort is also being expended in testing research models which may be used in such assessments. (author)

Superior memory efficiency of quantum devices for the simulation of continuous-time stochastic processes

Science.gov (United States)

Elliott, Thomas J.; Gu, Mile

2018-03-01

Continuous-time stochastic processes pervade everyday experience, and the simulation of models of these processes is of great utility. Classical models of systems operating in continuous-time must typically track an unbounded amount of information about past behaviour, even for relatively simple models, enforcing limits on precision due to the finite memory of the machine. However, quantum machines can require less information about the past than even their optimal classical counterparts to simulate the future of discrete-time processes, and we demonstrate that this advantage extends to the continuous-time regime. Moreover, we show that this reduction in the memory requirement can be unboundedly large, allowing for arbitrary precision even with a finite quantum memory. We provide a systematic method for finding superior quantum constructions, and a protocol for analogue simulation of continuous-time renewal processes with a quantum machine.

Swift observations of the accreting millisecond pulsar IGR J17498-2921 : From outburst to quiescence

NARCIS (Netherlands)

Linares, M.; Bozzo, E.; Altamirano, D.; Degenaar, N.; Wijnands, R.; Soleri, P.; Belloni, T.; Di Salvo, T.; D'Ai, A.; Papitto, A.; Riggio, A.; Burderi, L.

Swift has been monitoring the accreting millisecond pulsar IGR J17498-2921 since the start of its outburst in 2011 August 12 (ATels #3551, #3555, #3556). We detected two X-ray bursts on Aug. 18 and 28. During the first ~12 days the average persistent XRT count rate remained approximately constant at

Swift Trust: Implications for Whole of Government/Comprehensive Approach (WoG/CA) Missions

Science.gov (United States)

2014-09-01

Hinde, J Groebel (Eds.), Cooperation and Prosocial Behavior , (pp. 167 182). New York: Cambridge University Press. Bradley, W. E. & Vozikis, G. S. (2004...trust. Academy of Management Review, 20(3), 709-734. McAllister, D. (1995). Affect - and cognition -based trust as foundations for interpersonal...Fortunately research from within the organizational behavior realm has demonstrated that there are times when ‘swift trust’ may exist, that is, where

Explicit episodic memory for sensory-discriminative components of capsaicin-induced pain: immediate and delayed ratings.

Science.gov (United States)

Jantsch, H H F; Gawlitza, M; Geber, C; Baumgärtner, U; Krämer, H H; Magerl, W; Treede, R D; Birklein, F

2009-05-01

Pain memory is thought to affect future pain sensitivity and thus contribute to clinical pain conditions. Systematic investigations of the human capacity to remember sensory features of experimental pain are sparse. In order to address long-term pain memory, nine healthy male volunteers received intradermal injections of three doses of capsaicin (0.05, 1 and 20 microg, separated by 15 min breaks), each given three times in a balanced design across three sessions at one week intervals. Pain rating was performed using a computerized visual analogue scale (0-100) digitized at 1/s, either immediately online or one hour or one day after injection. Subjects also recalled their pains one week later. Capsaicin injection reliably induced a dose-dependent flare (pmemory traces. These results indicate a reliable memory for magnitude and duration of experimentally induced pain. The data further suggest that the consolidation of this memory is an important interim stage, and may take up to one day.

Analogue computer display of accelerator beam optics

International Nuclear Information System (INIS)

Brand, K.

1984-01-01

Analogue computers have been used years ago by several authors for the design of magnetic beam handling systems. At Bochum a small analogue/hybrid computer was combined with a particular analogue expansion and logic control unit for beam transport work. This apparatus was very successful in the design and setup of the beam handling system of the tandem accelerator. The center of the stripper canal was the object point for the calculations, instead of the high energy acceleration tube a drift length was inserted into the program neglecting the weak focusing action of the tube. In the course of the installation of a second injector for heavy ions it became necessary to do better calculations. A simple method was found to represent accelerating sections on the computer and a particular way to simulate thin lenses was adopted. The analogue computer system proved its usefulness in the design and in studies of the characteristics of different accelerator installations over many years. The results of the calculations are in very good agreement with real accelerator data. The apparatus is the ideal tool to demonstrate beam optics to students and accelerator operators since the effect of a change of any of the parameters is immediately visible on the oscilloscope

Voluntary and involuntary emotional memory following an analogue traumatic stressor: the differential effects of communality in men and women.

Science.gov (United States)

Kamboj, Sunjeev K; Oldfield, Lucy; Loewenberger, Alana; Das, Ravi K; Bisby, James; Brewin, Chris R

2014-12-01

Men and women show differences in performance on emotional processing tasks. Sex also interacts with personality traits to affect information processing. Here we examine effects of sex, and two personality traits that are differentially expressed in men and women - instrumentality and communality - on voluntary and involuntary memory for distressing video-footage. On session one, participants (n = 39 men; 40 women) completed the Bem Sex-Role Inventory, which assesses communal and instrumental traits. After viewing film-footage of death/serious injury, participants recorded daily involuntary memories (intrusions) relating to the footage on an online diary for seven days, returning on day eight for a second session to perform a voluntary memory task relating to the film. Communality interacted with sex such that men with higher levels of communality reported more frequent involuntary memories. Alternatively, a communality × sex interaction reflected a tendency for women with high levels of communality to perform more poorly on the voluntary recognition memory task. The study involved healthy volunteers with no history of significant psychological disorder. Future research with clinical populations will help to determine the generalizability of the current findings. Communality has separate effects on voluntary and involuntary emotional memory. We suggest that high levels of communality in men and women may confer vulnerability to the negative effects of stressful events either through the over-encoding of sensory/perceptual-information in men or the reduced encoding of contextualised, verbally-based, voluntarily accessible representations in women. Copyright © 2014 Elsevier Ltd. All rights reserved.

Rapid and reversible impairments of short- and long-term social recognition memory are caused by acute isolation of adult rats via distinct mechanisms.

Science.gov (United States)

Shahar-Gold, Hadar; Gur, Rotem; Wagner, Shlomo

2013-01-01

Mammalian social organizations require the ability to recognize and remember individual conspecifics. This social recognition memory (SRM) can be examined in rodents using their innate tendency to investigate novel conspecifics more persistently than familiar ones. Here we used the SRM paradigm to examine the influence of housing conditions on the social memory of adult rats. We found that acute social isolation caused within few days a significant impairment in acquisition of short-term SRM of male and female rats. Moreover, SRM consolidation into long-term memory was blocked following only one day of social isolation. Both impairments were reversible, but with different time courses. Furthermore, only the impairment in SRM consolidation was reversed by systemic administration of arginine-vasopressin (AVP). In contrast to SRM, object recognition memory was not affected by social isolation. We conclude that acute social isolation rapidly induces reversible changes in the brain neuronal and molecular mechanisms underlying SRM, which hamper its acquisition and completely block its consolidation. These changes occur via distinct, AVP sensitive and insensitive mechanisms. Thus, acute social isolation of rats swiftly causes changes in their brain and interferes with their normal social behavior.

Rapid and reversible impairments of short- and long-term social recognition memory are caused by acute isolation of adult rats via distinct mechanisms.

Directory of Open Access Journals (Sweden)

Hadar Shahar-Gold

Full Text Available Mammalian social organizations require the ability to recognize and remember individual conspecifics. This social recognition memory (SRM can be examined in rodents using their innate tendency to investigate novel conspecifics more persistently than familiar ones. Here we used the SRM paradigm to examine the influence of housing conditions on the social memory of adult rats. We found that acute social isolation caused within few days a significant impairment in acquisition of short-term SRM of male and female rats. Moreover, SRM consolidation into long-term memory was blocked following only one day of social isolation. Both impairments were reversible, but with different time courses. Furthermore, only the impairment in SRM consolidation was reversed by systemic administration of arginine-vasopressin (AVP. In contrast to SRM, object recognition memory was not affected by social isolation. We conclude that acute social isolation rapidly induces reversible changes in the brain neuronal and molecular mechanisms underlying SRM, which hamper its acquisition and completely block its consolidation. These changes occur via distinct, AVP sensitive and insensitive mechanisms. Thus, acute social isolation of rats swiftly causes changes in their brain and interferes with their normal social behavior.

Analogue Signal Processing: Collected Papers 1996-97

DEFF Research Database (Denmark)

1997-01-01

This document is a collection of the papers presented at international conferences and in international journals by the analogue signal processing group of the Department of Information Technology, Technical University of Denmark, in 1996 and 1997.......This document is a collection of the papers presented at international conferences and in international journals by the analogue signal processing group of the Department of Information Technology, Technical University of Denmark, in 1996 and 1997....

Intrusive images and voluntary memory for affective pictures: contextualization and dual-task interference.

Science.gov (United States)

Krans, Julie; Langner, Oliver; Reinecke, Andrea; Pearson, David G

2013-12-01

The present study addressed the role of context information and dual-task interference during the encoding of negative pictures on intrusion development and voluntary recall. Healthy participants were shown negative pictures with or without context information. Pictures were either viewed alone or concurrently with a visuospatial or verbal task. Participants reported their intrusive images of the pictures in a diary. At follow-up, perceptual and contextual memory was tested. Participants in the context group reported more intrusive images and perceptual voluntary memory than participants in the no context group. No effects of the concurrent tasks were found on intrusive image frequency, but perceptual and contextual memory was affected according to the cognitive load of the task. The analogue method cannot be generalized to real-life trauma and the secondary tasks may differ in cognitive load. The findings challenge a dual memory model of PTSD but support an account in which retrieval strategy, rather than encoding processes, accounts for the experience of involuntary versus voluntary recall. Copyright © 2013 Elsevier Ltd. All rights reserved.

Irradiation effects of swift heavy ions on gallium arsenide, silicon and silicon diodes

International Nuclear Information System (INIS)

Bhoraskar, V.N.

2001-01-01

The irradiation effects of high energy lithium, boron, oxygen and silicon ions on crystalline silicon, gallium arsenide, porous silicon and silicon diodes were investigated. The ion energy and fluence were varied over the ranges 30 to 100 MeV and 10 11 to 10 14 ions/cm 2 respectively. Semiconductor samples were characterized with the x-ray fluorescence, photoluminescence, thermally stimulated exo-electron emission and optical reflectivity techniques. The life-time of minority carriers in crystalline silicon was measured with a pulsed electron beam and the lithium depth distribution in GaAs was measured with the neutron depth profiling technique. The diodes were characterized through electrical measurements. The results of optical reflectivity, life-time of minority carriers and photoluminescence show that swift heavy ions induce defects in the surface region of crystalline silicon. In the ion-irradiated GaAs, migration of silicon, oxygen and lithium atoms from the buried region towards the surface was observed, with orders of magnitude enhancement in the diffusion coefficients. Enhancement in the photoluminescence intensity was observed in the GaAs and porous silicon samples that, were irradiated with silicon ions. The trade-off between the turn-off time and the voltage, drop in diodes irradiated with different swift heavy ions was also studied. (author)

Rapid thermal and swift heavy ion induced annealing of Co ion implanted GaN films

International Nuclear Information System (INIS)

Baranwal, V.; Pandey, A. C.; Gerlach, J. W.; Rauschenbach, B.; Karl, H.; Kanjilal, D.; Avasthi, D. K.

2008-01-01

Thin epitaxial GaN films grown on 6H-SiC(0001) substrates were implanted with 180 keV Co ions at three different fluences. As-implanted samples were characterized with secondary ion mass spectrometry and Rutherford backscattering spectrometry to obtain the Co depth profiles and the maximum Co concentrations. As-implanted samples were annealed applying two different techniques: rapid thermal annealing and annealing by swift heavy ion irradiation. Rapid thermal annealing was done at two temperatures: 1150 deg. C for 20 s and 700 deg. C for 5 min. 200 MeV Ag ions at two fluences were used for annealing by irradiation. Crystalline structure of the pristine, as-implanted, and annealed samples was investigated using x-ray diffraction, and the results were compared. Improvement of the crystalline quality was observed for rapid thermal annealed samples at the higher annealing temperature as confirmed with rocking curve measurements. The results indicate the presence of Co clusters in these annealed samples. Swift heavy ion irradiation with the parameters chosen for this study did not lead to a significant annealing

Análogos de insulina Insulin analogues

Directory of Open Access Journals (Sweden)

Manuel E. Licea Puig

2006-12-01

diabetes mellitus (DM. The recombinant technology of deoxyribonucleic acid (DNA has allowed the development of human insulin; however, this has not totally solved the problems related to immunogenecity, among other problems. Therefore, the new technologies are applied to create insulin analogues. It is our purpose to review relevant pharmacological and clinical aspects related to the insulin analogues, as well as their usefulness in the treatment of DM. The insulin analogues result from biochemical modifications of human insulin. These modifications of the insulin molecule alter not only the absorption, but also the beginning and duration of the action, which offer advantages over the conventional insulins. At present, there are three rapid acting insulin analogues: insulin lispro, insulin aspart and glulisine; and three long acting analogues; glargine, detemir and albulin. Albulin is the latest long acting analogue reported. At present, it is being subjected to various in vitro and in vivo studies. Besides, there have been developed diverse formulations where the rapid acting insulin analogues are premixed with the long acting analogues. The rapid acting insulin analogues have showed a modest global benefit against the conventional insulins in type 1 diabetics. The long acting analogues focus their attention in those persons with DM with nocturnal hypoglycemic episodes. Longer term studies are necessary to confirm the safety and benefits of these preparations, as well as to determine their effect on the micro- and macroangiopathic complications of DM.

Development of Nanoporous Polymer Membranes by Swift Heavy Ion Irradiation

Science.gov (United States)

Dinesh, Divya; Predeep, P.

2011-10-01

This study reveals the preparation of conical pores in polyethylene terephthalate (PET) by track etching. The polymer membrane is etched from one side by keeping between the clamps of conductivity cell followed by irradiation with swift heavy ion of 197Au. Electrical stopping supports chemical stopping. During etching process current is measured as a function of time till a sharp increase -breakthrough-observed. After etching membranes are thoroughly washed with stopping solution and water. Resultant films are characterized using Optical microscope and field emission scanning electron microscopy. Polymer films with uniform pores can be a cheaper templating material in the fields of photonic crystals and micro- electronics.

Optical Precursors to Black Hole X-Ray Binary Outbursts: An Evolving Synchrotron Jet Spectrum in Swift J1357.2–0933

Science.gov (United States)

Russell, David M.; Qasim, Ahlam Al; Bernardini, Federico; Plotkin, Richard M.; Lewis, Fraser; Koljonen, Karri I. I.; Yang, Yi-Jung

2018-01-01

We present six years of optical monitoring of the black hole (BH) candidate X-ray binary Swift J1357.2–0933, during and since its discovery outburst in 2011. On these long timescales, the quiescent light curve is dominated by high amplitude, short-term (seconds–days) variability spanning ∼2 mag, with an increasing trend of the mean flux from 2012 to 2017 that is steeper than in any other X-ray binary found to date (0.17 mag yr‑1). We detected the initial optical rise of the 2017 outburst of Swift J1357.2–0933, and we report that the outburst began between 2017 April 1 and 6. Such a steep optical flux rise preceding an outburst is expected according to disk instability models, but the high amplitude variability in quiescence is not. Previous studies have shown that the quiescent spectral, polarimetric, and rapid variability properties of Swift J1357.2–0933 are consistent with synchrotron emission from a weak compact jet. We find that a variable optical/infrared spectrum is responsible for the brightening: a steep, red spectrum before and soon after the 2011 outburst evolves to a brighter, flatter spectrum since 2013. The evolving spectrum appears to be due to the jet spectral break shifting from the infrared in 2012 to the optical in 2013, then back to the infrared by 2016–2017 while the optical remains relatively bright. Swift J1357.2–0933 is a valuable source to study BH jet physics at very low accretion rates and is possibly the only quiescent source in which the optical jet properties can be regularly monitored.

Chemopreventive properties of curcumin analogues ...

African Journals Online (AJOL)

Chemopreventive properties of curcumin analogues, ... These compounds .... using microscope with 400 × magnification. APC ... Figure 3: Microscopic images of rat colorectal tissue stained with APC rabbit polyclonal antibody with different.

Mechanism of the monoclinic-to-tetragonal phase transition induced in zirconia and hafnia by swift heavy ions

International Nuclear Information System (INIS)

Benyagoub, Abdenacer

2005-01-01

Recent results demonstrated that defect formation or amorphization are not the only structural changes induced by swift heavy ions in crystalline materials and that under certain circumstances crystalline-to-crystalline phase transitions can also occur. For instance, it was found that both zirconia and hafnia transform from the monoclinic to the tetragonal phase with a kinetics involving a double ion impact process. In order to understand the origin of this ion-beam induced phase transition, the behavior of these twin oxides was analyzed and compared. In fact, the likeness of these materials offered the unique opportunity to impose drastic constraints on the possible models proposed to explain the creation of atomic displacements in the wake of swift heavy ions. This comparison clearly suggests that the thermal spike is the most appropriate process which governs the transition from the monoclinic to the tetragonal phase in zirconia and hafnia

Analogues of luteinizing hormone-releasing hormone containing cytotoxic groups.

Science.gov (United States)

Janáky, T; Juhász, A; Bajusz, S; Csernus, V; Srkalovic, G; Bokser, L; Milovanovic, S; Redding, T W; Rékási, Z; Nagy, A

1992-02-01

In an attempt to produce better cytotoxic analogues, chemotherapeutic antineoplastic radicals including an alkylating nitrogen mustard derivative of D-phenylalanine (D-melphalan), reactive cyclopropane, anthraquinone derivatives [2-(hydroxymethyl)anthraquinone and the anticancer antibiotic doxorubicin], and an antimetabolite (methotrexate) were coupled to suitably modified agonists and antagonists of luteinizing hormone-releasing hormone (LH-RH). Analogues with D-lysine6 and D-ornithine6 or N epsilon-(2,3-diaminopropionyl)-D-lysine and N delta-(2,3-diaminopropionyl)-D-ornithine were used as carriers for one or two cytotoxic moieties. The enhanced biological activities produced by the incorporation of D amino acids into position 6 of the agonistic analogues were further increased by the attachment of hydrophobic cytotoxic groups, resulting in compounds with 10-50 times higher activity than LH-RH. Most of the monosubstituted agonistic analogues showed high affinities for the membrane receptors of human breast cancer cells, while the receptor binding affinities of peptides containing two cytotoxic side chains were lower. Antagonistic carriers [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Trp3,Arg5,D-Lys6,D-Ala10] LH-RH [where Nal(2) is 3-(2-naphthyl)alanine], [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Trp3,Arg5,N epsilon-(2,3-diaminopropionyl)-D-Lys6,D-Ala10]LH-RH, and their D-Pal(3)3 homologs [Pal(3) is 3-(3-pyridyl)alanine] as well as [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Pal(3)3,Tyr5,N epsilon-(2,3-diamino-propionyl)-D-Lys6,D-Ala10]LH-RH were linked to cytotoxic compounds. The hybrid molecules inhibited ovulation in rats at doses of 10 micrograms and suppressed LH release in vitro. The receptor binding of cytotoxic analogues was decreased compared to the precursor peptides, although analogues with 2-(hydroxymethyl)anthraquinone hemiglutarate had high affinities. All of the cytotoxic analogues tested inhibited [3H]thymidine incorporation into DNA in cultures of human breast and prostate cancer cell lines

Insulin analogues and severe hypoglycaemia in type 1 diabetes

DEFF Research Database (Denmark)

Kristensen, P L; Hansen, L S; Jespersen, M J

2012-01-01

The effect of insulin analogues on glycaemic control is well-documented, whereas the effect on avoidance of severe hypoglycaemia remains tentative. We studied the frequency of severe hypoglycaemia in unselected patients with type 1 diabetes treated with insulin analogues, human insulin, or mixed...

How stakeholders view the use of analogues in safety cases: PAMINA

International Nuclear Information System (INIS)

Atherton, Elizabeth; Bailey, Lucy

2008-01-01

The aim of this presentation is to provide an overview of some research that has been undertaken in the UK to investigate stakeholders' views of analogues. There are various reasons for using analogues including: to try and explain difficult concepts; to compare disposal facility features with familiar and/or natural systems; to provide an alternative, non-numerical line of reasoning to support the Safety Case conclusions; to provide evidence of behaviour over very long timescales, that cannot be achieved in the laboratory. There are some dangers when using analogues that people should be aware of: the analogue conditions may not be the same as those found in a disposal facility, so the analogue may have limited application. Some analogues may have negative implications, for example artefacts that have corroded. Analogues can be taken too far and used in inappropriate ways to try and support an assumption. So it is important to find out how stakeholders view the use of analogues in a safety case. NDA is involved in an EC funded project called Pamina (Performance Assessment Methodologies in Application). The project involves 26 partners from 11 European countries, plus other associated members and runs for 3 years from October 2006 to October 2009. The NDA is involved in several parts of the project: Exploring issues of modelling uncertainty; Evaluating effectiveness of approaches for communicating safety cases with stakeholders. NDA ran a workshop in October 2007 in Manchester. The aims of the workshop were to explore how different methods of communicating aspects of a safety case were received by stakeholders. The workshop presented stakeholders with: Examples of different repository concepts; Descriptions of barrier performance; Different ways of presenting numerical results; Use of natural analogues

Defining reference conditions for acidified waters using a modern analogue approach

International Nuclear Information System (INIS)

Simpson, Gavin L.; Shilland, Ewan M.; Winterbottom, Julie M.; Keay, Janey

2005-01-01

Analogue matching is a palaeolimnological technique that aims to find matches for fossil sediment samples from a set of modern surface sediment samples. Modern analogues were identified that closely matched the pre-disturbance conditions of eight of the UK Acid Waters Monitoring Network (AWMN) lakes using diatom- and cladoceran-based analogue matching. These analogue sites were assessed in terms of hydrochemistry, aquatic macrophytes and macro-invertebrates as to their suitability for defining wider hydrochemical and biological reference conditions for acidified sites within the AWMN. The analogues identified for individual AWMN sites show a close degree of similarity in terms of their hydrochemical characteristics, aquatic macrophytes and, to a lesser extent, macro-invertebrate fauna. The reference conditions of acidified AWMN sites are inferred to be less acidic than today and to support a wider range of acid-sensitive aquatic macrophyte and macro-invertebrate taxa than that recorded in the AWMN lakes over the period of monitoring since 1988. - The use of a palaeolimnological technique to identify modern ecological reference analogues for acidified lakes is demonstrated

Studying frequency processing of the brain to enhance long-term memory and develop a human brain protocol.

Science.gov (United States)

Friedrich, Wernher; Du, Shengzhi; Balt, Karlien

2015-01-01

The temporal lobe in conjunction with the hippocampus is responsible for memory processing. The gamma wave is involved with this process. To develop a human brain protocol, a better understanding of the relationship between gamma and long-term memory is vital. A more comprehensive understanding of the human brain and specific analogue waves it uses will support the development of a human brain protocol. Fifty-eight participants aged between 6 and 60 years participated in long-term memory experiments. It is envisaged that the brain could be stimulated through binaural beats (sound frequency) at 40 Hz (gamma) to enhance long-term memory capacity. EEG recordings have been transformed to sound and then to an information standard, namely ASCII. Statistical analysis showed a proportional relationship between long-term memory and gamma activity. Results from EEG recordings indicate a pattern. The pattern was obtained through the de-codification of an EEG recording to sound and then to ASCII. Stimulation of gamma should enhance long term memory capacity. More research is required to unlock the human brains' protocol key. This key will enable the processing of information directly to and from human memory via gamma, the hippocampus and the temporal lobe.

iOS Game Development using SpriteKit Framework with Swift Programming Language

OpenAIRE

Gurung, Lal

2016-01-01

iOS is a mobile operating system for Apple manufactured phones and tablets. Mobile Gaming Industries are growing very fast, and compatibility with iOS is becoming very popular among game developers. The aim of this Bachelor’s thesis was to find the best available game development tools for iOS platform. The 2D game named Lapland was developed using Apple’s own native framework, SpriteKit. The game was written with the SpriteKit programming language. The combination of SpriteKit and Swift...

Alligator Rivers Analogue project. Application of scenario development method in evaluation of the Koongarra Analogue. Final Report - Volume 16

Energy Technology Data Exchange (ETDEWEB)

Skagius, K [Kemakta Consultants co., Stockholm (Sweden); Wingefors, S [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

1993-12-31

The study of natural analogues has been established as one of the most important methods for validation of concepts and models applied for the assessment of long-term performance of repositories for nuclear waste. The objectives of such studies range from detailed investigations of processes and features on a small scale to attempts of explaining the evolution of whole sites. For studies of specific processes it may well be as important to consider the larger scale settings as boundary conditions. This appreciation of context and an integrated view may be as important for evaluation of most natural analogues as for performance assessments. This is more evident the more the evaluation depends on a knowledge about the evolution of the natural analogue. The attempted formulation of scenarios of the Koongarra Analogue has been based on the external conditions and external features. A rapid weathering of the host rock, i.e. the chlorite schist, is assumed to have started around the onset of the Pleistocene Ice Age (ca 1.6 Ma BP). The eventual oxidation and mobilization of the uranium ore could then have occurred under unsaturated or saturated conditions. This leads to the following major scenarios: (1) Uranyl Phosphates formed under unsaturated conditions, with a periodical evolution of the dispersion fan in conjunction with alternating dry (glacial) and wet (interglacial) periods during the Pleistocene Ice Age; (2) Uranyl Phosphates formed under unsaturated conditions as a single event, taking place either early or late during the Pleistocene Ice Age; (3)Uranyl Phosphates formed under saturated conditions, in conjunction with periods of higher and lower flow due to the climatic cycling. Although the original objectives may not have been fully achieved, this work is believed to contribute to a better understanding of the Koongarra Analogue as well as to give a basis for further scenario work

Alligator Rivers Analogue project. Application of scenario development method in evaluation of the Koongarra Analogue. Final Report - Volume 16

Energy Technology Data Exchange (ETDEWEB)

Skagius, K. [Kemakta Consultants co., Stockholm (Sweden); Wingefors, S. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

1992-12-31

The study of natural analogues has been established as one of the most important methods for validation of concepts and models applied for the assessment of long-term performance of repositories for nuclear waste. The objectives of such studies range from detailed investigations of processes and features on a small scale to attempts of explaining the evolution of whole sites. For studies of specific processes it may well be as important to consider the larger scale settings as boundary conditions. This appreciation of context and an integrated view may be as important for evaluation of most natural analogues as for performance assessments. This is more evident the more the evaluation depends on a knowledge about the evolution of the natural analogue. The attempted formulation of scenarios of the Koongarra Analogue has been based on the external conditions and external features. A rapid weathering of the host rock, i.e. the chlorite schist, is assumed to have started around the onset of the Pleistocene Ice Age (ca 1.6 Ma BP). The eventual oxidation and mobilization of the uranium ore could then have occurred under unsaturated or saturated conditions. This leads to the following major scenarios: (1) Uranyl Phosphates formed under unsaturated conditions, with a periodical evolution of the dispersion fan in conjunction with alternating dry (glacial) and wet (interglacial) periods during the Pleistocene Ice Age; (2) Uranyl Phosphates formed under unsaturated conditions as a single event, taking place either early or late during the Pleistocene Ice Age; (3)Uranyl Phosphates formed under saturated conditions, in conjunction with periods of higher and lower flow due to the climatic cycling. Although the original objectives may not have been fully achieved, this work is believed to contribute to a better understanding of the Koongarra Analogue as well as to give a basis for further scenario work

Alligator Rivers Analogue project. Application of scenario development method in evaluation of the Koongarra Analogue. Final Report - Volume 16

International Nuclear Information System (INIS)

Skagius, K.; Wingefors, S.

1992-01-01

The study of natural analogues has been established as one of the most important methods for validation of concepts and models applied for the assessment of long-term performance of repositories for nuclear waste. The objectives of such studies range from detailed investigations of processes and features on a small scale to attempts of explaining the evolution of whole sites. For studies of specific processes it may well be as important to consider the larger scale settings as boundary conditions. This appreciation of context and an integrated view may be as important for evaluation of most natural analogues as for performance assessments. This is more evident the more the evaluation depends on a knowledge about the evolution of the natural analogue. The attempted formulation of scenarios of the Koongarra Analogue has been based on the external conditions and external features. A rapid weathering of the host rock, i.e. the chlorite schist, is assumed to have started around the onset of the Pleistocene Ice Age (ca 1.6 Ma BP). The eventual oxidation and mobilization of the uranium ore could then have occurred under unsaturated or saturated conditions. This leads to the following major scenarios: (1) Uranyl Phosphates formed under unsaturated conditions, with a periodical evolution of the dispersion fan in conjunction with alternating dry (glacial) and wet (interglacial) periods during the Pleistocene Ice Age; (2) Uranyl Phosphates formed under unsaturated conditions as a single event, taking place either early or late during the Pleistocene Ice Age; (3)Uranyl Phosphates formed under saturated conditions, in conjunction with periods of higher and lower flow due to the climatic cycling. Although the original objectives may not have been fully achieved, this work is believed to contribute to a better understanding of the Koongarra Analogue as well as to give a basis for further scenario work

Design requirements for the SWIFT instrument

International Nuclear Information System (INIS)

Rahnama, P; McDade, I; Shepherd, G; Gault, W

2013-01-01

The Stratospheric Wind Interferometer for Transport studies (SWIFT) instrument is a proposed limb-viewing satellite instrument that employs the method of Doppler Michelson interferometry to measure stratospheric wind velocities and ozone densities in the altitude range of 15–45 km. The values of the main instrument parameters including filter system parameters and Michelson interferometer parameters are derived using simulations and analyses. The system design requirements for the instrument and spacecraft are presented and discussed. Some of the retrieval-imposed design requirements are also discussed. Critical design issues are identified. The design optimization process is described. The sensitivity of wind measurements to instrument characteristics is investigated including the impact on critical design issues. Using sensitivity analyses, the instrument parameters were iteratively optimized in order to meet the science objectives. It is shown that wind measurements are sensitive to the thermal sensitivity of the instrument components, especially the narrow filter and the Michelson interferometer. The optimized values of the main system parameters including Michelson interferometer optical path difference, instrument visibility, instrument responsivity and knowledge of spacecraft velocity are reported. This work also shows that the filter thermal drift and the Michelson thermal drift are two main technical risks. (paper)

Diminution and Magnification: Gothic Images in Jonathan Swift's Gulliver's Travels (1726

Directory of Open Access Journals (Sweden)

Baker Mohammad Jamil Bani-Khair

2017-11-01

Full Text Available This paper studies two significant techniques in Jonathon Swift's Gulliver's Travels (1726 which are diminution and magnification as influential devices which show gothic and supernatural images throughout the whole novel. The paper investigated and analyzed the supernatural images in terms of the gothic fantasy and its elements such as the ones that relate to the sublime, horror, and exotic images. The study concluded that the use of those two techniques of diminution and magnification tend to create several and various effects on the plot, characters, and the narrative development which increase the level of suspense in a critical framework.

Swift heavy ion irradiation induced electrical degradation in deca-nanometer MOSFETs

Energy Technology Data Exchange (ETDEWEB)

Ma, Yao; Yang, Zhimei; Gong, Min [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China); Key Laboratory of High Energy Density Physics and Technology of Ministry of Education, Sichuan University, Chengdu 610064 (China); Gao, Bo; Li, Yun; Lin, Wei; Li, Jinbo; Xia, Zhuohui [Key Laboratory for Microelectronics, College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China)

2016-09-15

In this work, degradation of the electrical characteristics of 65 nm nMOSFETs under swift heavy ion irradiation is investigated. It was found that a heavy ion can generate a localized region of physical damage (ion latent track) in the gate oxide. This is the likely cause for the increased gate leakage current and soft breakdown (SBD) then hard breakdown (HBD) of the gate oxide. Except in the case of HBD, the devices retain their functionality but with degraded transconductance. The degraded gate oxide exhibits early breakdown behavior compatible with the model of defect generation and percolation path formation in the percolation model.

Cobalamin analogues in humans

DEFF Research Database (Denmark)

Hardlei, Tore Forsingdal; Obeid, Rima; Herrmann, Wolfgang

2013-01-01

BACKGROUND: Haptocorrin (HC) carries cobalamin analogues (CorA), but whether CorA are produced in the body is unknown. All cobalamins (Cbl) to the foetus are delivered by the Cbl-specific protein transcobalamin (TC), and therefore analysis of cord serum for CorA may help to clarify the origin...

Concise synthesis of new bridged-nicotine analogues

DEFF Research Database (Denmark)

Crestey, François; Hooyberghs, Geert; Kristensen, Jesper Langgaard

2012-01-01

This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively.......This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively....

Deficiencies in fat-soluble vitamins in long-term users of somatostatin analogue

NARCIS (Netherlands)

Fiebrich, H. -B.; van den Berg, G.; Kema, I. P.; Links, T. P.; Kleibeuker, J. H.; van Beek, A. P.; Walenkamp, A. M. E.; Sluiter, W. J.; de Vries, E. G. E.

2010-01-01

P>Background Somatostatin analogues are administered to control hormone hypersecretion in acromegaly and carcinoid patients. Somatostatin analogues can increase fat in the stools, which can lead to loss of fat-soluble vitamins. The effect of long-term somatostatin analogue use on vitamin levels

Climate Analogues for agricultural impact projection and adaptation – a reliability test

Directory of Open Access Journals (Sweden)

Swen P.M. Bos

2015-10-01

Full Text Available The climate analogue approach is often considered a valuable tool for climate change impact projection and adaptation planning, especially for complex systems that cannot be modelled reliably. Important examples are smallholder farming systems using agroforestry or other mixed-cropping approaches. For the projected climate at a particular site of interest, the analogue approach identifies locations where the current climate is similar to these projected conditions. By comparing baseline-analogue site pairs, information on climate impacts and opportunities for adaptation can be obtained. However, the climate analogue approach is only meaningful, if climate is a dominant driver of differences between baseline and analogue site pairs. For a smallholder farming setting on Mt. Elgon in Kenya, we tested this requirement by comparing yield potentials of maize and coffee (obtained from the IIASA Global Agro-ecological Zones dataset among 50 close analogue sites for different future climate scenarios and models, and by comparing local ecological knowledge and farm characteristics for one baseline-analogue pair.Yield potentials among the 50 closest analogue locations varied strongly within all climate scenarios, hinting at factors other than climate as major drivers of what the analogue approach might interpret as climate effects. However, on average future climatic conditions seemed more favourable to maize and coffee cultivation than current conditions. The detailed site comparison revealed substantial differences between farms in important characteristics, such as farm size and presence of cash crops, casting doubt on the usefulness of the comparison for climate change analysis. Climatic constraints were similar between sites, so that no apparent lessons for adaptation could be derived. Pests and diseases were also similar, indicating that climate change may not lead to strong changes in biotic constraints at the baseline site in the near future. From

Fermi/LAT Observations of Swift/BAT Seyfert Galaxies: On the Contribution of Radio-Quiet Active Galactic Nuclei to the Extragalactic gamma-Ray Background

Science.gov (United States)

Teng, Stacy H.; Mushotzky, Richard F.; Sambruna, Rita M.; Davis, David S.; Reynolds, Christopher S.

2011-01-01

We present the analysis of 2.1 years of Fermi Large Area Telescope (LAT) data on 491 Seyfert galaxies detected by the Swift Burst Alert Telescope (BAT) survey. Only the two nearest objects, NGC 1068 and NGC 4945, which were identified in the Fermi first year catalog, are detected. Using Swift/BAT and radio 20 cm fluxes, we define a new radio-loudness parameter R(sub X,BAT) where radio-loud objects have logR(sub X,BAT) > -4.7. Based on this parameter, only radio-loud sources are detected by Fermi/LAT. An upper limit to the flux of the undetected sources is derived to be approx.2x10(exp -11) photons/sq cm/s, approximately seven times lower than the observed flux of NGC 1068. Assuming a median redshift of 0.031, this implies an upper limit to the gamma-ray (1-100 GeV) luminosity of BAT Seyfert galaxies with significant Fermi/LAT detections. A majority of these objects do not have Swift/BAT counterparts, but their possible optical counterparts include blazars, flat-spectrum radio quasars, and quasars.

Machine-z: Rapid Machine-Learned Redshift Indicator for Swift Gamma-Ray Bursts

Science.gov (United States)

Ukwatta, T. N.; Wozniak, P. R.; Gehrels, N.

2016-01-01

Studies of high-redshift gamma-ray bursts (GRBs) provide important information about the early Universe such as the rates of stellar collapsars and mergers, the metallicity content, constraints on the re-ionization period, and probes of the Hubble expansion. Rapid selection of high-z candidates from GRB samples reported in real time by dedicated space missions such as Swift is the key to identifying the most distant bursts before the optical afterglow becomes too dim to warrant a good spectrum. Here, we introduce 'machine-z', a redshift prediction algorithm and a 'high-z' classifier for Swift GRBs based on machine learning. Our method relies exclusively on canonical data commonly available within the first few hours after the GRB trigger. Using a sample of 284 bursts with measured redshifts, we trained a randomized ensemble of decision trees (random forest) to perform both regression and classification. Cross-validated performance studies show that the correlation coefficient between machine-z predictions and the true redshift is nearly 0.6. At the same time, our high-z classifier can achieve 80 per cent recall of true high-redshift bursts, while incurring a false positive rate of 20 per cent. With 40 per cent false positive rate the classifier can achieve approximately 100 per cent recall. The most reliable selection of high-redshift GRBs is obtained by combining predictions from both the high-z classifier and the machine-z regressor.

Science and technology on the nanoscale with swift heavy ions in matter

Energy Technology Data Exchange (ETDEWEB)

Neumann, Reinhard, E-mail: r.neumann@gsi.de

2013-11-01

Swift heavy ions have stimulated developments of science and technology on the nanoscale due to the specific manner of transferring their kinetic energy in a solid successively in small portions along their trajectories. They thus create absolutely straight, almost cylindrical, and very narrow damage trails of diameter 5–10 nm. In various materials, such as polymers, a suitable etchant can transform these tracks into narrow channels of cylindrical, conical, or other desired shapes. These channels represent a starting point particularly for two major fields: they can be chemically modified to control small species and act, e.g., as sensors and transmitters of specific biomolecules. Irradiation of a sample with only one heavy ion allows the fabrication of single-nanochannel devices enabling measurements of enormous sensitivity. Filling nanochannels with a material provides nanowires. These objects of restricted dimensions exhibit finite-size and quantum behavior and give rise to a broad range of fundamental and applied research. This contribution briefly recollects microtechnological achievements with swift heavy ions that began already in the 1970s, preparing the ground for gradual size decrease down to the nanoscopic objects now under study. Various examples of material modifications on the nanoscale are presented, including recent results obtained with nanochannels and nanowires. Emerging developments are addressed, encompassing in situ recording of processes in biological cells stimulated by well-aimed ion irradiation, the fabrication of three-dimensional nanowire architectures, and plasmonic effects in nanowires.

Sandia Wake Imaging System Field Test Report: 2015 Deployment at the Scaled Wind Farm Technology (SWiFT) Facility.

Energy Technology Data Exchange (ETDEWEB)

Naughton, Brian Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Herges, Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-10-01

This report presents the objectives, configuration, procedures, reporting , roles , and responsibilities and subsequent results for the field demonstration of the Sandia Wake Imaging System (SWIS) at the Sandia Scaled Wind Farm Technology (SWiFT) facility near Lubbock, Texas in June and July 2015.

Analogue Electrical Circuit for Simulation of the Duffing-Holmes Equation

DEFF Research Database (Denmark)

Tamaseviciute, E.; Tamasevicius, A.; Mykolaitis, G.

2008-01-01

An extremely simple second order analogue electrical circuit for simulating the two-well Duffing-Holmes mathematical oscillator is described. Numerical results and analogue electrical simulations are illustrated with the snapshots of chaotic waveforms, phase portraits (Lissajous figures...

3-alkyl fentanyl analogues: Structure-activity-relationship study

OpenAIRE

Vučković, Sonja; Savić-Vujović, Katarina; Srebro, Dragana; Ivanović, Milovan; Došen-Mićović, Ljiljana; Stojanović, Radan; Prostran, Milica

2012-01-01

Introduction. Fentanyl belongs to 4-anilidopiperidine class of synthetic opioid analgesics. It is characterized by high potency, rapid onset and short duration of action. A large number of fentanyl analogues have been synthesized so far, both to establish the structure-activity-relationship (SAR) and to find novel, clinically useful analgesic drugs. Objective. In this study, newly synthesized 3-alkyl fentanyl analogues were examined for analgesic activity and compared with fentanyl. Methods. ...

Effect of swift heavy ion irradiation on bare and coated ZnS quantum dots

International Nuclear Information System (INIS)

Chowdhury, S.; Hussain, A.M.P.; Ahmed, G.A.; Singh, F.; Avasthi, D.K.; Choudhury, A.

2008-01-01

The present study compares structural and optical modifications of bare and silica (SiO 2 ) coated ZnS quantum dots under swift heavy ion (SHI) irradiation. Bare and silica coated ZnS quantum dots were prepared following an inexpensive chemical route using polyvinyl alcohol (PVA) as the dielectric host matrix. X-ray diffraction (XRD) and transmission electron microscopy (TEM) study of the samples show the formation of almost spherical ZnS quantum dots. The UV-Vis absorption spectra reveal blue shift relative to bulk material in absorption energy while photoluminescence (PL) spectra suggests that surface state and near band edge emissions are dominating in case of bare and coated samples, respectively. Swift heavy ion irradiation of the samples was carried out with 160 MeV Ni 12+ ion beam with fluences 10 12 to 10 13 ions/cm 2 . Size enhancement of bare quantum dots after irradiation has been indicated in XRD and TEM analysis of the samples which has also been supported by optical absorption spectra. However similar investigations on irradiated coated quantum dots revealed little change in quantum dot size and emission. The present study thus shows that the coated ZnS quantum dots are stable upon SHI irradiation compared to the bare one

Rheological and physical characteristics of crustal-scaled materials for centrifuge analogue modelling

Science.gov (United States)

Waffle, Lindsay; Godin, Laurent; Harris, Lyal B.; Kontopoulou, M.

2016-05-01

We characterize a set of analogue materials used for centrifuge analogue modelling simulating deformation at different levels in the crust simultaneously. Specifically, we improve the rheological characterization in the linear viscoelastic region of materials for the lower and middle crust, and cohesive synthetic sands without petroleum-binding agents for the upper crust. Viscoelastic materials used in centrifuge analogue modelling demonstrate complex dynamic behaviour, so viscosity alone is insufficient to determine if a material will be an effective analogue. Two series of experiments were conducted using an oscillating bi-conical plate rheometer to measure the storage and loss moduli and complex viscosities of several modelling clays and silicone putties. Tested materials exhibited viscoelastic and shear-thinning behaviour. The silicone putties and some modelling clays demonstrated viscous-dominant behaviour and reached Newtonian plateaus at strain rates clays demonstrated elastic-dominant power-law relationships. Based on these results, the elastic-dominant modelling clay is recommended as an analogue for basement cratons. Inherently cohesive synthetic sands produce fine-detailed fault and fracture patterns, and developed thrust, strike-slip, and extensional faults in simple centrifuge test models. These synthetic sands are recommended as analogues for the brittle upper crust. These new results increase the accuracy of scaling analogue models to prototype. Additionally, with the characterization of three new materials, we propose a complete lithospheric profile of analogue materials for centrifuge modelling, allowing future studies to replicate a broader range of crustal deformation behaviours.

SPECTRAL LAGS AND THE LAG-LUMINOSITY RELATION: AN INVESTIGATION WITH SWIFT BAT GAMMA-RAY BURSTS

International Nuclear Information System (INIS)

Ukwatta, T. N.; Dhuga, K. S.; Eskandarian, A.; Maximon, L. C.; Parke, W. C.; Stamatikos, M.; Sakamoto, T.; Barthelmy, S. D.; Gehrels, N.; Norris, J. P.

2010-01-01

Spectral lag, the time difference between the arrival of high-energy and low-energy photons, is a common feature in gamma-ray bursts (GRBs). Norris et al. reported a correlation between the spectral lag and the isotropic peak luminosity of GRBs based on a limited sample. More recently, a number of authors have provided further support for this correlation using arbitrary energy bands of various instruments. In this paper, we report on a systematic extraction of spectral lags based on the largest Swift sample to date of 31 GRBs with measured redshifts. We extracted the spectral lags for all combinations of the standard Swift hard X-ray energy bands: 15-25 keV, 25-50 keV, 50-100 keV, and 100-200 keV and plotted the time dilation corrected lag as a function of isotropic peak luminosity. The mean value of the correlation coefficient for various channel combinations is -0.68 with a chance probability of ∼0.7 x 10 -3 . In addition, the mean value of the power-law index is 1.4 ± 0.3. Hence, our study lends support to the existence of a lag-luminosity correlation, albeit with large scatter.

Diffusion kinetics of the glucose/glucose oxidase system in swift heavy ion track-based biosensors

Energy Technology Data Exchange (ETDEWEB)

Fink, Dietmar, E-mail: fink@xanum.uam.mx [Nuclear Physics Institute, 25068 Řež (Czech Republic); Departamento de Fisica, Universidad Autónoma Metropolitana-Iztapalapa, PO Box 55-534, 09340 México, DF (Mexico); Vacik, Jiri; Hnatowicz, V. [Nuclear Physics Institute, 25068 Řež (Czech Republic); Muñoz Hernandez, G. [Departamento de Fisica, Universidad Autónoma Metropolitana-Iztapalapa, PO Box 55-534, 09340 México, DF (Mexico); Garcia Arrelano, H. [Departamento de Ciencias Ambientales, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana-Lerma, Av. de las Garzas No. 10, Col. El Panteón, Lerma de Villada, Municipio de Lerma, Estado de México CP 52005 (Mexico); Alfonta, Lital [Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, PO Box 653, Beer-Sheva 84105 (Israel); Kiv, Arik [Department of Materials Engineering, Ben-Gurion University of the Negev, PO Box 653, Beer-Sheva 84105 (Israel)

2017-05-01

Highlights: • Application of swift heavy ion tracks in biosensing. • Obtaining yet unknown diffusion coefficients of organic matter across etched ion tracks. • Obtaining diffusion coefficients of organics in etched ion tracks of biosensors. • Comparison with Renkin’s equation to predict the effective etched track diameter in the given experiments. - Abstract: For understanding of the diffusion kinetics and their optimization in swift heavy ion track-based biosensors, recently a diffusion simulation was performed. This simulation aimed at yielding the degree of enrichment of the enzymatic reaction products in the highly confined space of the etched ion tracks. A bunch of curves was obtained for the description of such sensors that depend only on the ratio of the diffusion coefficient of the products to that of the analyte within the tracks. As hitherto none of these two diffusion coefficients is accurately known, the present work was undertaken. The results of this paper allow one to quantify the previous simulation and hence yield realistic predictions of glucose-based biosensors. At this occasion, also the influence of the etched track radius on the diffusion coefficients was measured and compared with earlier prediction.

Tailoring optical properties of TiO2-Cr co-sputtered films using swift heavy ions

Science.gov (United States)

Gupta, Ratnesh; Sen, Sagar; Phase, D. M.; Avasthi, D. K.; Gupta, Ajay

2018-05-01

Effect of 100 MeV Au7+ ion irradiation on structure and optical properties of Cr-doped TiO2 films has been studied using X-ray photoelectron spectroscopy, soft X-ray absorption spectroscopy, UV-Visible spectroscopy, X-ray reflectivity, and atomic force microscopy. X-ray reflectivity measurement implied that film thickness reduces as a function of ion fluence while surface roughness increases. The variation in surface roughness is well correlated with AFM results. Ion irradiation decreases the band gap energy of the film. Swift heavy ion irradiation enhances the oxygen vacancies in the film, and the extra electrons in the vacancies act as donor-like states. In valence band spectrum, there is a shift in the Ti3d peak towards lower energies and the shift is equivalent to the band gap energy obtained from UV spectrum. Evidence for band bending is also provided by the corresponding Ti XPS peak which exhibits a shift towards lower energy due to the downward band bending. X-ray absorption studies on O Kand Cr L3,2 edges clearly indicate that swift heavy ion irradiation induces formation of Cr-clusters in TiO2 matrix.

Alkyne End Group Production in Polymeric Materials Induced by Swift Heavy Ion Irradiations

Institute of Scientific and Technical Information of China (English)

无

2001-01-01

Swift heavy ions in matter lose energy mainly through electronic processes.Since the energy deposition is centered in a very small region with a very high energy density,new effects such as production of alkyne end group can be induced.In this work,PET,PS,PC and PI films are irradiated with Ar,Kr,Xe and U ions and the relationship of the alkyne end group production with electronic energy loss is studied by Fourier transformed infrared infrared(FTLR)spectra measurements.

Labelling and evaluation of new stabilised neurotensin (8-13) analogues for SPET

International Nuclear Information System (INIS)

Chavatte, K.; Terriere, D.; Jeannin, L.

1998-01-01

Neurotensin (8-13) analogues were biologically stabilised by replacement of the peptide bond between amino acids 8 and 9 by the reduced ψ(CH 2 -NH) isostere. DTPA analogues for In-111 labelling and 2-bromo-phenyl-acetyl analogues for radioiodination, showed receptor affinities in the low nanomolar range in combination with a biological half live in human plasma up to 275 minutes. Biodistribution studies in male Wistar rats of metabolically stabilised and non-stabilised 111 In-DTPA-NT(8-13) analogues showed a major clearance from the blood through the kidneys. 125 I-labelled Neurotensin (8-13) analogues showed accumulation up to 2.2% of the injected dose per g tissue in the liver which might be an important disadvantage when diagnosis of tumours in the gut is aimed. It is strongly suggested that stabilised neurotensin (8-13) analogues whether labelled with In-111, I-123 and the near future with Tc-99m, may act as new potential peptidergic radiopharmaceuticals for SPET diagnosis of different NT-receptor positive tumours like non-endocrine pancreas carcinoma, small cell lung carcinoma or colon adeno carcinoma. It is enticing to speculate that metabolically stabilised Neurotensin (8-13) analogues labelled with an appropriate isotope might be useful in therapy of different human cancers. (author)

Discovery of an Accreting Millisecond Pulsar in the Eclipsing Binary System SWIFT J1749.4-2807

NARCIS (Netherlands)

Altamirano, D.; Cavecchi, Y.; Patruno, A.; Watts, A.; Linares, M.; Degenaar, N.; Kalamkar, M.; van der Klis, M.; Rea, N.; Casella, P.; Padilla, M. Armas; Kaur, R.; Yang, Y. J.; Soleri, P.; Wijnands, R.

2011-01-01

We report on the discovery and the timing analysis of the first eclipsing accretion-powered millisecond X-ray pulsar (AMXP): SWIFT J1749.4-2807. The neutron star rotates at a frequency of similar to 517.9 Hz and is in a binary system with an orbital period of 8.8 hr and a projected semimajor axis of

Thymidine analogues to assess microperfusion in human tumors

International Nuclear Information System (INIS)

Janssen, Hilde L.; Ljungkvist, Anna S.; Rijken, Paul F.; Sprong, Debbie; Bussink, Jan; Kogel, Albert J. van der; Haustermans, Karin M.; Begg, Adrian C.

2005-01-01

Purpose: To validate the use of the thymidine analogues as local perfusion markers in human tumors (no labeling indicates no perfusion) by comparison with the well-characterized perfusion marker Hoechst 33342. Methods and Materials: Human tumor xenografts from gliomas and head-and-neck cancers were injected with iododeoxyuridine (IdUrd) or bromodeoxyuridine (BrdUrd) and the fluorescent dye Hoechst 33342. In frozen sections, each blood vessel was scored for the presence of IdUrd/BrdUrd labeling and Hoechst in surrounding cells. The percentage of analogue-negative vessels was compared with the fraction of Hoechst-negative vessels. Collocalization of the two markers was also scored. Results: We found considerable intertumor variation in the fraction of perfused vessels, measured by analogue labeling, both in the human tumor xenografts and in a series of tumor biopsies from head-and-neck cancer patients. There was a significant correlation between the Hoechst-negative and IdUrd/BrdUrd-negative vessels in the xenografts (r 85, p = 0.0004), despite some mismatches on a per-vessel basis. Conclusions: Thymidine analogues can be successfully used to rank tumors according to their fraction of perfused vessels. Whether this fraction correlates with the extent of acute hypoxia needs further confirmation

Analogues of estradiol as potential breast tumor imaging agents

International Nuclear Information System (INIS)

Gibson, R.E.; Rzeszotarski, W.J.; Ferriera, N.L.; Jagoda, E.M.; Reba, R.C.; Eckelman, W.C.

1984-01-01

The radioiodinated analogue of estradiol, 11β-methoxy-17α-[/sup 125/I]iodovinylestradiol (MIVE/sub 2/), has been shown to be a good candidate for the imaging of estrogen dependent breast tumors. Although there has been no extensive study on the sensitivity of radiotracers of this type, the authors have not observed localization of the radiotracer in metastatic lesions containing less than 20 fmole estrogen receptor/mg protein or in bone metasteses. In order to improve the sensitivity, they have examined several structural analogues of moxestrol (the parent structure for MIVE/sub 2/) for affinity to the ER isolated from immature rat uterus. The 11β-ethyl analogue (EEE/sub 2/) of ethynyl estradiol (EE/sub 2/) exhibits the highest affinity with the 11β-methyl analogue second best. Although the lipophilicity is also very high this compound should not be much more lipophilic than 16-iodoestradiol or MIVE/sub 2/ since the introduction of iodine increases the log P by greater than 1. The distribution of the tritiated derivative of EEE/sub 2/ is under study

Iodination and stability of somatostatin analogues: comparison of iodination techniques. A practical overview.

Science.gov (United States)

de Blois, Erik; Chan, Ho Sze; Breeman, Wouter A P

2012-01-01

For iodination ((125/127)I) of tyrosine-containing peptides, chloramin-T, Pre-Coated Iodo-Gen(®) tubes and Iodo-Beads(®) (Pierce) are commonly used for in vitro radioligand investigations and there have been reliant vendors hereof for decades. However, commercial availability of these radio-iodinated peptides is decreasing. For continuation of our research in this field we investigated and optimized (radio-)iodination of somatostatin analogues. In literature, radioiodination using here described somatostatin analogues and iodination techniques are described separately. Here we present an overview, including High Performance Liquid Chromatography (HPLC) separation and characterisation by mass spectrometry, to obtain mono- and di-iodinated analogues. Reaction kinetics of (125/127)I iodinated somatostatin analogues were investigated as function of reaction time and concentration of reactants, including somatostatin analogues, iodine and oxidizing agent. To our knowledge, for the here described somatostatin analogues, no (127)I iodination and optimization are described. (Radio-)iodinated somatostatin analogues could be preserved with a >90% radiochemical purity for 1 month after reversed phase HPLC-purification.

From BPA to its analogues: Is it a safe journey?

Science.gov (United States)

Usman, Afia; Ahmad, Masood

2016-09-01

Bisphenol-A (BPA) is one of the most abundant synthetic chemicals in the world due to its uses in plastics. Its widespread exposure vis-a-vis low dose effects led to a reduction in its safety dose and imposition of ban on its use in infant feeding bottles. This restriction paved the way for the gradual market entry of its analogues. However, their structural similarity to BPA has put them under surveillance for endocrine disrupting potential. The application of these analogues is increasing and so are the studies reporting their toxicity. This review highlights the reasons which led to the ban of BPA and also reports the exposure and toxicological data available on its analogues. Hence, this compilation is expected to answer in a better way whether the replacement of BPA by these analogues is safer or more harmful? Copyright © 2016. Published by Elsevier Ltd.

Design of a saturated analogue and digital current transducer

International Nuclear Information System (INIS)

Pross, Alexander

2002-01-01

This project describes the development of a new analogue and digital current transducer, providing a range of new theoretical design methods for these novel devices. The main control feature is the limit cycling operation, and the novel use of the embedded sigma-delta modulator sensor structure to derive a low component count digital sensor. The research programme was initiated into the design, development and evaluation of a novel non-Hall sensing analogue and digital current transducer. These transducers are used for measurement of high currents in power systems applications. The investigation is concerned with a new design which uses a magnetic ferrite core without an air gap for current measurement. The motivation for this work was to design a new control circuit which provides a low component count, and utilises the non-linear properties of the magnetic ferrite core to transmit direct current. The use of a limit cycle control circuit was believed to be particularly suitable for the analogue and digital transducers, for two main reasons: the low component count, and the output signal is directly digital. In line with the motivations outlined above, the outcome of the research has witnessed the design, development and evaluation of a practically realisable analogue and digital current transducer. The design procedure, which is documented in this thesis, is considered to be a major contribution to the field of transducers design and development using a control systems approach. Mathematical models for both analogue and digital transducers were developed and the resulting model based predictions were found to be in good agreement with measured results. Simplification of the new model sensing device was achieved by approximating the non-linear ferrite core using FFT analysis. This is also considered to be a significant contribution. The development analogue and digital current censors employed a sampled data control systems design and utilised limit cycling

Natural analogues, paradigm for manmade repositories for radioactive wastes

International Nuclear Information System (INIS)

Pavelescu, M.; Pavelescu, A.

2004-01-01

Natural analogues are given by nature. They show the results of natural processes which have lasted thousands or millions of years. They provide an excellent example of what could happen in an underground site, offering in the same time the opportunity to test by observation and measurement, many of the geochemical processes that are expected to influence in a realistic and appropriate way, the predicted reliability of the radioactive waste repository over long periods of geological time. The natural analogue studies attempt to understand the multiprocessing complexity of the natural system, which contrasts with the limitations of the laboratory experiments and bring arguments to overcome the difficult time scale issue. By this the natural analogues are a useful paradigm for manmade repository for radioactive wastes. The paper discusses the implicit link in the public mind between natural analogues and manmade waste repository with an accent of the positive impact on public acceptance. It is also discussed the decisive qualities of the natural analogues concerning providing valid long term data and increasing the confidence of the public for manmade repositories. The debate is conducting in terms of sustainable development, having at base high-level principles in order to protect humans and their environment, both now and in the future, from potential hazards arising from such wastes. Safe radwaste management involves the application of technology and resources in a regulated manner so that the public, workers and the environment are protected in accordance with the accepted national and international standards. There are at least seven high-level principles which are mentioned in the paper. It is presented the general concept of the deep geological repository, very important for an acceptable solution for the management of nuclear waste, what is a prerequisite for a renewal of nuclear power. Further are introduced natural and archaeological (manufactured) analogue

Swift heavy ion induced phase transformation and thermoluminescence properties of zirconium oxide

Energy Technology Data Exchange (ETDEWEB)

Lokesha, H.S. [Physics R & D Centre, PES Institute of Technology, BSK 3rd Stage, Bangalore 560085 (India); Nagabhushana, K.R., E-mail: bhushankr@gmail.com [Physics R & D Centre, PES Institute of Technology, BSK 3rd Stage, Bangalore 560085 (India); Department of Physics, PES University, BSK 3rd Stage, Bangalore 560085 (India); Singh, Fouran [Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi 110 067 (India)

2016-07-15

Zirconium oxide (ZrO{sub 2}) powder is synthesized by combustion technique. XRD pattern of ZrO{sub 2} shows monoclinic phase with average crystallite size 35 nm. Pellets of ZrO{sub 2} are irradiated with 100 MeV swift Si{sup 7+}, Ni{sup 7+} and 120 MeV swift Ag{sup 9+} ions in the fluence range 3 × 10{sup 10}–3 × 10{sup 13} ions cm{sup −2}. XRD pattern show the main diffraction peak correspond to monoclinic and tetragonal phase of ZrO{sub 2} in 2θ range 27–33°. Structural phase transformation is observed for Ni{sup 7+} and Ag{sup 9+} ion irradiated samples at a fluence 1 × 10{sup 13} ions cm{sup −2} and 3 × 10{sup 12} ions cm{sup −2} respectively, since the deposited electronic energy loss exceeds an effective threshold (>12 keV nm{sup −1}). Phase transition induced by Ag{sup 9+} ion is nearly 2.9 times faster than Ni{sup 7+} ion at 1 × 10{sup 13} ions cm{sup −2}. Ag{sup 9+} ion irradiation leads two ion impact processes. Thermoluminescence (TL) glow curves exhibit two glows, a well resolved peak at ∼424 K and unresolved peak at 550 K for all SHI irradiated samples. TL response is decreased with increase of ion fluence. Beyond 3 × 10{sup 12} ions cm{sup −2}, samples don’t exhibit TL due to annihilation of defects.

Solid-phase synthesis of new saphenamycin analogues with antimicrobial activity

DEFF Research Database (Denmark)

Laursen, Jane B.; de Visser, P.C.; Nielsen, H.K.

2002-01-01

in parallel with a series of differently substituted benzoic acid derivatives. Treatment with TFA-CH2Cl2 (5:995) released the expected saphenamycin analogues into solution. These new analogues were purified, characterized and screened for antimicrobial activity against Bacillus subtilis and Proteus mirabilis...

Natural analogues for containment-providing barriers for a HLW repository in salt

Energy Technology Data Exchange (ETDEWEB)

Wolf, J.; Noseck, U.

2015-06-15

In 2005, a German research project was started to develop a novel approach to prove safety for a HLW repository in a salt formation, to refine the safety concept, to identify open scientific issues and to define necessary R&D work. This project aimed at identifying the key information for a HLW repository in salt. One important question is how this information may be best fulfilled by natural analogue studies. This question is answered by starting a review of the required key information needs of the safety case (post-closure phase) in order to assess whether or not these requirements can be supported by natural analogues information. In order to structure the review and to address the key elements of the safety concepts, three types of natural analogues are distinguished: (i) natural analogues for the integrity of the geological barrier, (ii) natural analogues for the integrity of the geotechnical barriers and (iii) natural analogues for release scenarios. For the safety case in salt type (i) and (ii) are of highest importance and are treated in this paper. The assessment documented in this paper on the one hand indicates the high potential benefit of natural analogues for a safety case in salt and on the other hand helps to focus the available human and financial resources for the safety case on the most safety-relevant aspects. (authors)

GnRH Analogues in the Prevention of Ovarian Hyperstimulation Syndrome

Science.gov (United States)

Alama, Pilar; Bellver, Jose; Vidal, Carmen; Giles, Juan

2013-01-01

The GnRH analogue (agonist and antagonist GnRH) changed ovarian stimulation. On the one hand, it improved chances of pregnancy to obtain more oocytes and better embryos. This leads to an ovarian hyper-response, which can be complicated by the ovarian hyperstimulation syndrome (OHSS). On the other hand, the GnRH analogue can prevent the incidence of OHSS: GnRH antagonist protocols, GnRH agonist for triggering final oocyte maturation, either together or separately, coasting, and the GnRH analogue may prove useful for avoiding OHSS in high-risk patients. We review these topics in this article. PMID:23825982

Evidence for quiescent synchrotron emission in the black hole X-ray transient Swift J1357.2–0933

Directory of Open Access Journals (Sweden)

Shahbaz T.

2013-12-01

Full Text Available We present high time-resolution optical and infrared observations of the edge-on black hole X-ray transient Swift J1357.2-0933. Our data taken in 2012 shows the system to be at its pre-outburst magnitude and so the system is in quiescence. In contrast to other X-ray transients, the quiescent light curves of Swift J1357.2-0933 do not show the secondary star’s ellipsoidal modulation. The optical and infrared light curves is dominated by variability with an optical fractional rms of about 20 per cent, much larger than what is observed in other systems. The quiescent ultraviolet to mid-IR spectral energy distribution in quiescence is dominated by a nonthermal component with a power–law index of −1.4, (the broad-band rms SED has a similar index which arises from optically thin synchrotron emission from a jet; the lack of a peak in the spectral energy distribution rules out advection-dominated models (based on [19].

Influence of prostaglandin analogues on epithelial cell proliferation and xenograft growth.

Science.gov (United States)

Tutton, P J; Barkla, D H

1980-01-01

The influence of two prostaglandin (PG) analogues, 16,16-dimethyl PG E2 and 16,16-dimethyl PG F2 alpha and of the cyclo-oxygenase inhibitor, flurbiprofen, on epithelial cell proliferation was assessed using a stathmokinetic technique. The epithelia examined were those of the jejunal crypts, the colonic crypts and that of dimethylhydrazine-induced adenocarcinomas of rat colon. The influence of the two prostaglandin analogues, and of flurbiprofen, on the growth of a human colorectal tumour propagated as xenografts in immune-deprived mice was also assessed. The PG E2 analogue transiently inhibited xenograft growth, but was without effect on the mitotic rate in the rat tissues. The PG F2 alpha analogue was also found to inhibit xenograft growth but, unlike the PG E2 analogue, it was found to be a strong inhibitor of cell proliferation in rat colonic tumours, and an accelerator of proliferation in jejunal-crypt cells. The only statistically significant effect of flurbiprofen was to accelerate cell division in the rat colonic tumours.

Optoelectronic properties of higher acenes, their BN analogue and substituted derivatives

International Nuclear Information System (INIS)

Armaković, Stevan; Armaković, Sanja J.; Holodkov, Vladimir; Pelemiš, Svetlana

2016-01-01

We have investigated optoelectronic properties of higher acenes: pentacene, hexacene, heptacene, octacene, nonacene, decacene and their boron-nitride (BN) analogues, within the framework of density functional theory (DFT). We have also investigated the optoelectronic properties of acenes modified by BN substitution. Calculated optoelectronic properties encompasses: oxidation and reduction potentials, electron and hole reorganization energies and energy difference between excited first singlet and triplet states ΔE(S_1−T_1). Oxidation and reduction potentials indicate significantly better stability of BN analogues, comparing with their all-carbon relatives. Although higher acenes possess lower electron and hole reorganization energies, with both best values much lower than 0.1 eV, their BN analogues also have competitive values of reorganization energies, especially for holes for which reorganization energy is also lower than 0.1 eV. On the other hand ΔE(S_1−T_1) is much better for BN analogues, having values that indicate that BN analogues are possible applicable for thermally activated delayed fluorescence. - Highlights: • Optoelectronic properties of structures based on higher acenes have been investigated. • Oxidation and reduction potentials together with reorganization energies are calculated. • TADF is analyzed through calculation of ΔE(S_1−T_1), which is much better for BN analogues. • Reorganization energies of acenes improve with the increase of number of benzene rings.

Swift observations of SDSS J141118.31+481257.6 during its first detected outburst

Science.gov (United States)

Sandoval, L. E. Rivera; Maccarone, T.

2018-05-01

We report Swift observations of the AM CVn-type system SDSS J141118.31+481257.6 (RA=14:11:18.31, Dec=+48:12:57.6) during its first ever recorded outburst. The system was detected by Tadashi Kojima on 2018-May-20 with a V magnitude of 12.6 +- 0.2 (http://ooruri.kusastro.kyoto-u.ac.jp/mailarchive/vsnet-alert/22176), an increase of 7 mags compared to any previous measurement in the same filter.

Cross-reactivity of amphetamine analogues with Roche Abuscreen radioimmunoassay reagents

International Nuclear Information System (INIS)

Cody, J.T.

1990-01-01

Cross-reactivity of amphetamine analogues with the Abuscreen amphetamine radioimmunoassay reagents was determined for both the standard and high specificity antibody systems. Compounds tested included 2-methoxyamphetamine, 4-hydroxymethamphetamine, 2,5-dimethoxyamphetamine (DMA), 4-bromo-2,5-dimethoxyamphetamine (DOB), 4-bromo-2,5-dimethoxy-beta-phenethylamine (BDMPEA), 3,4,5-trimethoxyamphetamine (TMA), 3,4-methylenedioxyamphetamine (MDA), N,N-dimethyl-3,4-methylenedioxyamphetamine and N-hydroxy-3,4-methylenedioxyamphetamine (N-OH MDA), 3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyethylamphetamine (MDEA), 2,5-dimethoxy-4-ethylamphetamine, 2,5-dimethoxy-4-methylamphetamine (DOM), and 3,4,5-trimethoxyphenethylamine (mescaline). Blank negative reference material was spiked with 1,000 to 100,000 ng/mL of the amphetamine analogue and used as sample in the assays. MDA was the only analogue that showed cross reactivity equal to or greater than that of amphetamine. None of the other analogue compounds demonstrated a positive result at even the highest concentration; however several showed depressed counts at various concentration levels

Biomimetic synthesis, antimicrobial, antileishmanial and antimalarial activities of euglobals and their analogues.

Science.gov (United States)

Bharate, Sandip B; Bhutani, Kamlesh K; Khan, Shabana I; Tekwani, Babu L; Jacob, Melissa R; Khan, Ikhlas A; Singh, Inder Pal

2006-03-15

In the present communication, naturally occurring phloroglucinol-monoterpene adducts, euglobals G1-G4 (3b/a and 4a/b) and 16 new analogues (13a/b-18a/b and 19-22) were synthesized by biomimetic approach. These synthetic compounds differ from natural euglobals in the nature of monoterpene and acyl functionality. All of these compounds were evaluated for their antibacterial, antifungal, antileishmanial and antimalarial activities. Analogue 17b possessed good antibacterial activity against methicillin-resistant Staphylococcus aureus, while analogues 19-22 possessed potent antifungal activity against Candida glabrata with IC50s ranging from 1.5 to 2.5 microg/mL. Euglobals along with all synthesized analogues exhibited antileishmanial activity. Amongst these, euglobal G2 (3a), G3 (4a) and analogues 13a and 14a showed potent antileishmanial activity with IC50s ranging from 2.8 to 3.9 microg/mL. Analogue 16a possessed antimalarial activity against chloroquine sensitive D6 clone of Plasmodium falciparum. None of the compounds showed toxicity against mammalian kidney fibroblasts (vero cells) upto the concentration of 4.76 microg/ml.

THREE-YEAR SWIFT-BAT SURVEY OF ACTIVE GALACTIC NUCLEI: RECONCILING THEORY AND OBSERVATIONS?

International Nuclear Information System (INIS)

Burlon, D.; Greiner, J.; Merloni, A.; Ajello, M.; Comastri, A.; Gehrels, N.

2011-01-01

It is well accepted that unabsorbed as well as absorbed active galactic nuclei (AGNs) are needed to explain the nature and shape of the Cosmic X-ray background (CXB), even if the fraction of highly absorbed objects (dubbed Compton-thick sources) still substantially escapes detection. We derive and analyze the absorption distribution using a complete sample of AGNs detected by Swift-BAT in the first three years of the survey. The fraction of Compton-thick AGNs represents only 4.6% of the total AGN population detected by Swift-BAT. However, we show that once corrected for the bias against the detection of very absorbed sources the real intrinsic fraction of Compton-thick AGNs is 20 -6 +9 %. We proved for the first time (also in the Burst Alert Telescope (BAT) band) that the anti-correlation of the fraction of absorbed AGNs and luminosity is tightly connected to the different behavior of the X-ray luminosity functions (XLFs) of absorbed and unabsorbed AGNs. This points toward a difference between the two subsamples of objects with absorbed AGNs being, on average, intrinsically less luminous than unobscured ones. Moreover, the XLFs show that the fraction of obscured AGNs might also decrease at very low luminosity. This can be successfully interpreted in the framework of a disk cloud outflow scenario as the disappearance of the obscuring region below a critical luminosity. Our results are discussed in the framework of population synthesis models and the origin of the CXB.

Diverse Long-term Variability of Five Candidate High-mass X-Ray Binaries from Swift Burst Alert Telescope Observations

Energy Technology Data Exchange (ETDEWEB)

Corbet, Robin H. D. [University of Maryland, Baltimore County, MD 21250 (United States); Coley, Joel B. [NASA Postdoctoral Program, and Astroparticle Physics Laboratory, Code 661 NASA Goddard Space Flight Center, Greenbelt Road, MD 20771 (United States); Krimm, Hans A., E-mail: corbet@umbc.edu [Universities Space Research Association, 10211 Wincopin Circle, Suite 500, Columbia, MD 21044 (United States)

2017-09-10

We present an investigation of long-term modulation in the X-ray light curves of five little-studied candidate high-mass X-ray binaries using the Swift Burst Alert Telescope. IGR J14488-5942 and AX J1700.2-4220 show strong modulation at periods of 49.6 and 44 days, respectively, which are interpreted as orbital periods of Be star systems. For IGR J14488-5942, observations with the Swift X-ray Telescope show a hint of pulsations at 33.4 s. For AX J1700.2-4220, 54 s pulsations were previously found with XMM-Newton . Swift J1816.7-1613 exhibits complicated behavior. The strongest peak in the power spectrum is at a period near 150 days, but this conflicts with a determination of a period of 118.5 days by La Parola et al. AX J1820.5-1434 has been proposed to exhibit modulation near 54 days, but the extended BAT observations suggest modulation at slightly longer than double this at approximately 111 days. There appears to be a long-term change in the shape of the modulation near 111 days, which may explain the apparent discrepancy. The X-ray pulsar XTE J1906+090, which was previously proposed to be a Be star system with an orbital period of ∼30 days from pulse timing, shows peaks in the power spectrum at 81 and 173 days. The origins of these periods are unclear, although they might be the orbital period and a superorbital period respectively. For all five sources, the long-term variability, together with the combination of orbital and proposed pulse periods, suggests that the sources contain Be star mass donors.

The Planetary Terrestrial Analogues Library (PTAL)

Science.gov (United States)

Werner, S. C.; Dypvik, H.; Poulet, F.; Rull Perez, F.; Bibring, J.-P.; Bultel, B.; Casanova Roque, C.; Carter, J.; Cousin, A.; Guzman, A.; Hamm, V.; Hellevang, H.; Lantz, C.; Lopez-Reyes, G.; Manrique, J. A.; Maurice, S.; Medina Garcia, J.; Navarro, R.; Negro, J. I.; Neumann, E. R.; Pilorget, C.; Riu, L.; Sætre, C.; Sansano Caramazana, A.; Sanz Arranz, A.; Sobron Grañón, F.; Veneranda, M.; Viennet, J.-C.; PTAL Team

2018-04-01

The Planetary Terrestrial Analogues Library project aims to build and exploit a spectral data base for the characterisation of the mineralogical and geological evolution of terrestrial planets and small solar system bodies.

Luciferase-Specific Coelenterazine Analogues for Optical Contamination-Free Bioassays

OpenAIRE

Ryo Nishihara; Masahiro Abe; Shigeru Nishiyama; Daniel Citterio; Koji Suzuki; Sung Bae Kim

2017-01-01

Spectral overlaps among the multiple optical readouts commonly cause optical contamination in fluorescence and bioluminescence. To tackle this issue, we created five-different lineages of coelenterazine (CTZ) analogues designed to selectively illuminate a specific luciferase with unique luciferase selectivity. In the attempt, we found that CTZ analogues with ethynyl or styryl groups display dramatically biased bioluminescence to specific luciferases and pHs by modifying the functional groups ...

15x optical zoom and extreme optical image stabilisation: diffraction limited integral field spectroscopy with the Oxford SWIFT spectrograph

Science.gov (United States)

Tecza, Matthias; Thatte, Niranjan; Clarke, Fraser; Lynn, James; Freeman, David; Roberts, Jennifer; Dekany, Richard

2012-09-01

When commissioned in November 2008 at the Palomar 200 inch Hale Telescope, the Oxford SWIFT I and z band integral field spectrograph, fed by the adaptive optics system PALAO, provided a wide (3×) range of spatial resolutions: three plate scales of 235 mas, 160 mas, and 80 mas per spaxel over a contiguous field-of-view of 89×44 pixels. Depending on observing conditions and guide star brightness we can choose a seeing limited scale of 235 mas per spaxel, or 160 mas and 80 mas per spaxel for very bright guide star AO with substantial increase of enclosed energy. Over the last two years PALAO was upgraded to PALM-3000: an extreme, high-order adaptive optics system with two deformable mirrors with more than 3000 actuators, promising diffraction limited performance in SWIFT's wavelength range. In order to take advantage of this increased spatial resolution we upgraded SWIFT with new pre-optics allowing us to spatially Nyquist sample the diffraction limited PALM-3000 point spread function with 16 mas resolution, reducing the spaxel scale by another factor of 5×. We designed, manufactured, integrated and tested the new pre-optics in the first half of 2011 and commissioned it in December 2011. Here we present the opto-mechanical design and assembly of the new scale changing optics, as well as laboratory and on-sky commissioning results. In optimal observing conditions we achieve substantial Strehl ratios, delivering the near diffraction limited spatial resolution in the I and z bands.

Synthesis and antioxidant activity of peptide-based ebselen analogues.

Science.gov (United States)

Satheeshkumar, Kandhan; Mugesh, Govindasamy

2011-04-18

A series of di- and tripeptide-based ebselen analogues has been synthesized. The compounds were characterized by (1)H, (13)C, and (77)Se NMR spectroscopy and mass spectral techniques. The glutathione peroxidase (GPx)-like antioxidant activity has been studied by using H(2)O(2) , tert-butyl hydroperoxide (tBuOOH), and cumene hydroperoxide (Cum-OOH) as substrates, and glutathione (GSH) as a cosubstrate. Although all the peptide-based compounds have a selenazole ring similar to that of ebselen, the GPx activity of these compounds highly depends on the nature of the peptide moiety attached to the nitrogen atom of the selenazole ring. It was observed that the introduction of a phenylalanine (Phe) amino acid residue in the N-terminal reduces the activity in all three peroxide systems. On the other hand, the introduction of aliphatic amino acid residues such as valine (Val) significantly enhances the GPx activity of the ebselen analogues. The difference in the catalytic activity of dipeptide-based ebselen derivatives can be ascribed mainly to the change in the reactivity of these compounds toward GSH and peroxide. Although the presence of the Val-Ala-CO(2) Me moiety facilitates the formation of a catalytically active selenol species, the reaction of ebselen analogues that has a Phe-Ile-CO(2) Me residue with GSH does not generate the corresponding selenol. To understand the antioxidant activity of the peptide-based ebselen analogues in the absence of GSH, these compounds were studied for their ability to inhibit peroxynitrite (PN)-mediated nitration of bovine serum albumin (BSA) and oxidation of dihydrorhodamine 123. In contrast to the GPx activity, the PN-scavenging activity of the Phe-based peptide analogues was found to be comparable to that of the Val-based compounds. However, the introduction of an additional Phe residue to the ebselen analogue that had a Val-Ala dipeptide significantly reduced the potency of the parent compound in PN-mediated nitration. Copyright �

SWIFT/UVOT GRISM MONITORING OF NGC 5548 IN 2013: AN ATTEMPT AT Mg ii REVERBERATION MAPPING

Energy Technology Data Exchange (ETDEWEB)

Cackett, E. M.; Troyer, J. [Department of Physics and Astronomy, Wayne State University, 666 W. Hancock St, Detroit, MI 48201 (United States); Gültekin, K. [Department of Astronomy, University of Michigan, 1085 S. University Ave, Ann Arbor, MI 48109 (United States); Bentz, M. C. [Department of Physics and Astronomy, Georgia State University, Atlanta, GA 30303 (United States); Fausnaugh, M. M.; Peterson, B. M. [Department of Astronomy, The Ohio State University, 140 West 18th Ave, Columbus, OH 43210 (United States); Vestergaard, M., E-mail: ecackett@wayne.edu [Dark Cosmology Centre, The Niels Bohr Institute, Juliane Maries Vej 30, DK-2100 Copenhagen Ø (Denmark)

2015-09-10

Reverberation-mapping-based scaling relations are often used to estimate the masses of black holes from single-epoch spectra of active galactic nuclei (AGNs). While the radius–luminosity relation that is the basis of these scaling relations is determined using reverberation mapping of the Hβ line in nearby AGNs, the scaling relations are often extended to use other broad emission lines, such as Mg ii, in order to get black hole masses at higher redshifts when Hβ is redshifted out of the optical waveband. However, there is no radius–luminosity relation determined directly from Mg ii. Here, we present an attempt to perform reverberation mapping using Mg ii in the well-studied nearby Seyfert 1 NGC 5548. We used Swift to obtain UV grism spectra of NGC 5548 once every two days from 2013 April to September. Concurrent photometric UV monitoring with Swift provides a well determined continuum light curve that shows strong variability. The Mg ii emission line, however, is not strongly correlated with the continuum variability, and there is no significant lag between the two. We discuss these results in the context of using Mg ii scaling relations to estimate high-redshift black hole masses.

Conjugate dynamical systems: classical analogue of the quantum energy translation

International Nuclear Information System (INIS)

Torres-Vega, Gabino

2012-01-01

An aspect of quantum mechanics that has not been fully understood is the energy shift generated by the time operator. In this study, we introduce the use of the eigensurfaces of dynamical variables and commutators in classical mechanics to study the classical analogue of the quantum translation of energy. We determine that there is a conjugate dynamical system that is conjugate to Hamilton's equations of motion, and then we generate the analogue of the time operator and use it in the translation of points along the energy direction, i.e. the classical analogue of the Pauli theorem. The theory is illustrated with a nonlinear oscillator model. (paper)

Coupled chemical reactions in dynamic nanometric confinement: VII. Biosensors based on swift heavy ion tracks with membranes

Czech Academy of Sciences Publication Activity Database

Fink, Dietmar; Munoz, G. H.; García Arellano, H.; Alfonta, L.; Vacík, Jiří; Kiv, A.; Hnatowicz, Vladimír

2017-01-01

Roč. 172, 1-2 (2017), s. 159-173 ISSN 1042-0150 R&D Projects: GA ČR(CZ) GBP108/12/G108 Institutional support: RVO:61389005 Keywords : biotechnology * tracks * swift heavy ions * polymers * etching Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders OBOR OECD: Nano-materials (production and properties) Impact factor: 0.443, year: 2016

Luciferase-Specific Coelenterazine Analogues for Optical Contamination-Free Bioassays.

Science.gov (United States)

Nishihara, Ryo; Abe, Masahiro; Nishiyama, Shigeru; Citterio, Daniel; Suzuki, Koji; Kim, Sung Bae

2017-04-19

Spectral overlaps among the multiple optical readouts commonly cause optical contamination in fluorescence and bioluminescence. To tackle this issue, we created five-different lineages of coelenterazine (CTZ) analogues designed to selectively illuminate a specific luciferase with unique luciferase selectivity. In the attempt, we found that CTZ analogues with ethynyl or styryl groups display dramatically biased bioluminescence to specific luciferases and pHs by modifying the functional groups at the C-2 and C-6 positions of the imidazopyradinone backbone of CTZ. The optical contamination-free feature was exemplified with the luciferase-specific CTZ analogues, which illuminated anti-estrogenic and rapamycin activities in a mixture of optical probes. This unique bioluminescence platform has great potential for specific and high throughput imaging of multiple optical readouts in bioassays without optical contamination.

NuSTAR and SWIFT Observations of the Black Hole Candidate XTE J1908+094 during its 2013 Outburst

DEFF Research Database (Denmark)

Tao, Lian; Tomsick, John A.; Walton, Dominic J.

2015-01-01

The black hole (BH) candidate XTE J1908+094 went into outburst for the first time since 2003 in 2013 October. We report on an observation with the Nuclear Spectroscopic Telescope Array (NuSTAR) and monitoring observations with Swift during the outburst. NuSTAR caught the source in the soft state...

Sensitivity of groundwater recharge using climatic analogues and HYDRUS-1D

Directory of Open Access Journals (Sweden)

B. Leterme

2012-08-01

Full Text Available The sensitivity of groundwater recharge to different climate conditions was simulated using the approach of climatic analogue stations, i.e. stations presently experiencing climatic conditions corresponding to a possible future climate state. The study was conducted in the context of a safety assessment of a future near-surface disposal facility for low and intermediate level short-lived radioactive waste in Belgium; this includes estimation of groundwater recharge for the next millennia. Groundwater recharge was simulated using the Richards based soil water balance model HYDRUS-1D and meteorological time series from analogue stations. This study used four analogue stations for a warmer subtropical climate with changes of average annual precipitation and potential evapotranspiration from −42% to +5% and from +8% to +82%, respectively, compared to the present-day climate. Resulting water balance calculations yielded a change in groundwater recharge ranging from a decrease of 72% to an increase of 3% for the four different analogue stations. The Gijon analogue station (Northern Spain, considered as the most representative for the near future climate state in the study area, shows an increase of 3% of groundwater recharge for a 5% increase of annual precipitation. Calculations for a colder (tundra climate showed a change in groundwater recharge ranging from a decrease of 97% to an increase of 32% for four different analogue stations, with an annual precipitation change from −69% to −14% compared to the present-day climate.

Optoelectronic properties of higher acenes, their BN analogue and substituted derivatives

Energy Technology Data Exchange (ETDEWEB)

Armaković, Stevan, E-mail: stevan.armakovic@df.uns.ac.rs [University of Novi Sad, Faculty of Sciences, Department of Physics, Trg Dositeja Obradovića 4, 21000, Novi Sad (Serbia); Armaković, Sanja J. [University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Trg Dositeja Obradovića 3, 21000, Novi Sad (Serbia); Holodkov, Vladimir [Educons University, Faculty of Sport and Tourism - TIMS, Radnička 30a, 21000, Novi Sad (Serbia); Pelemiš, Svetlana [University of East Sarajevo, Faculty of Technology, Karakaj bb, 75400, Zvornik, Republic of Srpska, Bosnia and Herzegovina (Bosnia and Herzegovina)

2016-02-15

We have investigated optoelectronic properties of higher acenes: pentacene, hexacene, heptacene, octacene, nonacene, decacene and their boron-nitride (BN) analogues, within the framework of density functional theory (DFT). We have also investigated the optoelectronic properties of acenes modified by BN substitution. Calculated optoelectronic properties encompasses: oxidation and reduction potentials, electron and hole reorganization energies and energy difference between excited first singlet and triplet states ΔE(S{sub 1}−T{sub 1}). Oxidation and reduction potentials indicate significantly better stability of BN analogues, comparing with their all-carbon relatives. Although higher acenes possess lower electron and hole reorganization energies, with both best values much lower than 0.1 eV, their BN analogues also have competitive values of reorganization energies, especially for holes for which reorganization energy is also lower than 0.1 eV. On the other hand ΔE(S{sub 1}−T{sub 1}) is much better for BN analogues, having values that indicate that BN analogues are possible applicable for thermally activated delayed fluorescence. - Highlights: • Optoelectronic properties of structures based on higher acenes have been investigated. • Oxidation and reduction potentials together with reorganization energies are calculated. • TADF is analyzed through calculation of ΔE(S{sub 1}−T{sub 1}), which is much better for BN analogues. • Reorganization energies of acenes improve with the increase of number of benzene rings.

Modeling Gamma-Ray Bursts in the Swift-Fermi era

International Nuclear Information System (INIS)

Hascoet, Romain

2012-01-01

Gamma-Ray Bursts (GRBs) are short flashes (≅ 10 ms-100 s) of gamma-rays (keV-MeV). These very bright and variable events are followed by an afterglow detected from the X-ray to the optical and radio domains, which decays rapidly and vanishes in a few days/weeks. Their extreme luminosity make them detectable up to cosmological distances (at least to a redshift of 9). They are produced by relativistic jets launched by a newborn compact object. The gamma-ray emission is attributed to internal mechanisms occurring within the jet and the afterglow to the deceleration by the circum-burst medium. The Swift satellite launched in 2004 has improved our knowledge of the afterglow (especially the early phase), while the Fermi satellite launched in 2008 has opened a new spectral window at high energy (above 100 MeV). My research work is in line with these recent observational breakthroughs which challenge the 'standard' GRB model that was established in the 90's. I have developed numerical tools that are well adapted to model in a consistent way the different emission phases experienced by the relativistic jet, from the photosphere to the deceleration. Using these tools, I have obtained several results that contribute to a better understanding of GRB physics. Regarding the GRB itself, I developed a new approach to compute precisely the opacity seen by a high-energy photon that propagates within a ultra-relativistic jet. By comparing predictions to Fermi observations, I obtain critical constraints on the physical conditions in the relativistic jet (especially the Lorentz factor). I have also tried to identify observational signatures that could help to discriminate between different emission models: spectral (optical and high energy emission, thermal component) and temporal (transition to the afterglow) signatures. Regarding the afterglow, I have carried on the development of an alternative model - the 'reverse shock' model - recently proposed to explain the phenomenological

Liposomes containing alkylated methotrexate analogues for phospholipase A(2) mediated tumor targeted drug delivery

DEFF Research Database (Denmark)

Kaasgaard, Thomas; Andresen, Thomas Lars; Jensen, Simon Skøde

2009-01-01

of alkylated compounds in liposomes, it was demonstrated that the MTX-analogue partitioned into the water phase and thereby became available for cell uptake. It was concluded that liposomes containing alkylated MTX-analogues show promise as a drug delivery system, although the MTX-analogue needs to be more......Two lipophilic methotrexate analogues have been synthesized and evaluated for cytotoxicity against KATO III and HT-29 human colon cancer cells. Both analogues contained a C-16-alkyl chain attached to the gamma-carboxylic acid and one of the analogues had an additional benzyl group attached...... cytotoxicity was incorporated into liposomes that were designed to be particularly Susceptible to a liposome degrading enzyme, secretory phospholipase A(2) (sPLA(2)), which is found in high concentrations in tumors of several different cancer types. Liposome incorporation was investigated by differential...

Insulin analogues: have they changed insulin treatment and improved glycaemic control?

DEFF Research Database (Denmark)

Madsbad, Sten

2002-01-01

To improve insulin therapy, new insulin analogues have been developed. Two fast-acting analogues with a more rapid onset of effect and a shorter duration of action combined with a low day-to-day variation in absorption rate are now available. Despite this favourable time-action profile most studies....... This is probably the main explanation for the absence of improvement in overall glycaemic control when compared with regular human insulin. A tendency to a reduction in hypoglycaemic events during treatment with fast-acting analogues has been observed in most studies. Recent studies have indicated that NPH insulin...... administered several times daily at mealtimes can improve glycaemic control without increasing the risk of hypoglycaemia. The fast-acting analogues are now also available as insulin mixed with NPH. Insulin glargine is a new long-acting insulin which is soluble and precipitates after injection, resulting...

BAT2 GRB Catalog - Prompt Emission Properties of Swift GRBs

International Nuclear Information System (INIS)

Sakamoto, T.; Barthelmy, S.; Gehrels, N.; Parsons, A.; Tueller, J.; Baumgartner, W.; Cummings, J.; Fenimore, E.; Palmer, D.; Krimm, H.; Markwardt, C.; Sato, G.; Stamatikos, M.; Ukwatta, T.

2010-01-01

We present the second Swift Burst Alert Telescope (BAT) catalog of gamma-ray bursts (GRBs), which contains 476 bursts detected by the BAT between 2004 December 19 and 2009 December 21. This catalog presents burst trigger time, location, 90% error radius, duration, fluence, peak flux, time-averaged spectral parameters and time-resolved spectral parameters measured by the BAT. The BAT T 90 duration peaks at 70 s. We confirm that the spectra of the BAT short-duration GRBs are generally harder than those of the long-duration GRBs. The observed durations of the BAT high redshift GRBs are not systematically longer than those of the moderate redshift GRBs. Furthermore, the observed spectra of the BAT high redshift GRBs are similar to or harder than the moderate redshift GRBs.

Synthesis of the 4’-desmethoxy analogue of RU79115

Directory of Open Access Journals (Sweden)

MICHEL KLICH

2004-11-01

Full Text Available The synthesis, and biological activity in vitro of the 4’-desmethoxy analogue (3 of RU 79115 (2 is described. Comparison of the biological activity of the two analogues clearly indicated the importance of the 4’-methoxy group in conferring good gyrase B inhibitory activity as well as antibacterial activity.

Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner

DEFF Research Database (Denmark)

Sandrini, Michael; Clausen, Anders; On, Stephen L. W.

2007-01-01

To investigate the bactericidal activity of antiviral and anticancer nucleoside analogues against a variety of pathogenic bacteria and characterize the activating enzymes, deoxyribonucleoside kinases (dNKs). Several FDA-approved nucleoside analogue drugs were screened for their potential bacteric......-specific manner. Therefore, nucleoside analogues have a potential to be employed as antibiotics in the fight against emerging multiresistant bacteria....

AN EXTRAORDINARY OUTBURST OF THE MAGNETAR SWIFT J1822.3–1606

Energy Technology Data Exchange (ETDEWEB)

Chakraborty, Manoneeta; Göğüş, Ersin [Sabancı University, Faculty of Engineering and Natural Sciences, Orhanlı Tuzla 34956, İstanbul (Turkey)

2015-08-20

The 2011 outburst of Swift J1822.3–1606 was extraordinary; periodic modulations at the spin period of the underlying neutron star were clearly visible, remarkably similar to what is observed during the decaying tail of magnetar giant flares. We investigated the temporal characteristics of X-ray emission during the early phases of the outburst. We performed a periodicity search with the spectral hardness ratio (HR) and found a coherent signal near the spin period of the neutron star, but with a lag of about 3 radians. Therefore, the HR is strongly anti-correlated with the X-ray intensity, which is also seen in the giant flares. We studied the time evolution of the pulse profile and found that it evolves from a complex morphology to a much simpler shape within about a month. Pulse profile simplification also takes place during the giant flares, but on a much shorter timescale of about a few minutes. We found that the amount of energy emitted during the first 25 days of the outburst is comparable to what was detected in minutes during the decaying tail of giant flares. Based on these similarities, we suggest that the triggering mechanisms of the giant flares and the magnetar outbursts are likely the same. We propose that the trapped fireball that develops in the magnetosphere at the onset of the outburst radiates away efficiently in minutes in magnetars exhibiting giant flares, while in other magnetars, such as Swift J1822.3–1606, the efficiency of radiation of the fireball is not as high and, therefore, lasts much longer.

The Swift Trust Partnership: A Project Management Exercise Investigating the Effects of Trust and Distrust in Outsourcing Relationships

Science.gov (United States)

Adler, Terry R.

2005-01-01

The Swift Trust exercise provides instructors with the opportunity to discuss the issues of managing trust and distrust perceptions in a team-based design. Lewicki, McAllister, and Bies's (1998) framework is used to allow students to experience the difficulties of deriving a common set of contract requirements based on team dynamics and…

X-RAY PROPERTIES OF THE NORTHERN GALACTIC CAP SOURCES IN THE 58 MONTH SWIFT/BAT CATALOG

International Nuclear Information System (INIS)

Vasudevan, Ranjan V.; Mushotzky, Richard F.; Shimizu, Thomas T.; Brandt, William N.; Schneider, Donald P.; Nousek, John; Winter, Lisa M.; Baumgartner, Wayne H.

2013-01-01

We present a detailed X-ray spectral analysis of the non-beamed, hard X-ray selected active galactic nuclei (AGNs) in the northern Galactic cap of the 58 month Swift Burst Alert Telescope (Swift/BAT) catalog, consisting of 100 AGNs with b > 50°. This sky area has excellent potential for further dedicated study due to a wide range of multi-wavelength data that are already available, and we propose it as a low-redshift analog to the 'deep field' observations of AGNs at higher redshifts (e.g., CDFN/S, COSMOS, Lockman Hole). We present distributions of luminosity, absorbing column density, and other key quantities for the catalog. We use a consistent approach to fit new and archival X-ray data gathered from XMM-Newton, Swift/XRT, ASCA, and Swift/BAT. We probe to deeper redshifts than the 9 month BAT catalog ((z) = 0.043 compared to (z) = 0.03 for the 9 month catalog), and uncover a broader absorbing column density distribution. The fraction of obscured (log N H ≥ 22) objects in the sample is ∼60%, and 43%-56% of the sample exhibits 'complex' 0.4-10 keV spectra. We present the properties of iron lines, soft excesses, and ionized absorbers for the subset of objects with sufficient signal-to-noise ratio. We reinforce previous determinations of the X-ray Baldwin (Iwasawa-Taniguchi) effect for iron Kα lines. We also identify two distinct populations of sources; one in which a soft excess is well-detected and another where the soft excess is undetected, suggesting that the process responsible for producing the soft excess is not at work in all AGNs. The fraction of Compton-thick sources (log N H > 24.15) in our sample is ∼9%. We find that 'hidden/buried AGNs' (which may have a geometrically thick torus or emaciated scattering regions) constitute ∼14% of our sample, including seven objects previously not identified as hidden. Compton reflection is found to be important in a large fraction of our sample using joint XMM-Newton+BAT fits ((R) = 2.7 ± 0.75), indicating

Reasoning by analogy: rational foundation of natural analogue studies

International Nuclear Information System (INIS)

Petit, J.-C.

1992-01-01

Long-term extrapolations concerning the safety of a nuclear waste repository cannot be satisfactorily made on the sole basis of short-term laboratory investigations. Most nuclear countries have hence developed an approach relying on the following research directions: 1. laboratory experiments; 2. in situ testing; 3. modeling; and 4. natural analogues, which are the only means by which very slow mechanisms can be identified and by which long-term predictions of models can be tested for pertinence (if not truly validated). Although the field of natural analogues has grown very rapidly in recent years, receiving support from varied specialists and institutions involved in radioactive waste disposal, there is not yet a full consensus on their actual usefulness. More problematic is the criticism sometimes made that analogical reasoning is not ''true science'' and that information retrieved from the study of natural analogues will always remain questionable. The present paper gives some clues about the exact status of reasoning by analogy, compared to more ''scientific'' ways of deriving information from investigated systems. It is not a thorough discussion of this very complex, and by far too philosophical issue but we hope, at least, to present to readers of papers devoted to natural analogue studies arguments showing that this approach has some sound foundation. (author)

A Low-cost Multi-channel Analogue Signal Generator

CERN Document Server

Muller, F; Shen, W; Stamen, R

2009-01-01

A scalable multi-channel analogue signal generator is presented. It uses a commercial low-cost graphics card with multiple outputs in a standard PC as signal source. Each color signal serves as independent channel to generate an analogue signal. A custom-built external PCB was developed to adjust the graphics card output voltage levels for a specific task, which needed differential signals. The system furthermore comprises a software package to program the signal shape. The implementation of the signal generator is presented as well as an application where it was successfully utilized.

A regulator's perspective on the use of analogues for regulatory confidence

International Nuclear Information System (INIS)

Ruiz, Carmen

2008-01-01

The NAA Study, promoted and coordinated by the CSN, was carried out in collaboration with ENRESA by CIEMAT and three Spanish Universities UZ, UDC and UCM. The 3 year Study, included in the CSN's R and D Programme, started in 1999, is focussed on Deep Geological disposal (DGD). CSN motivation for NA Analogues arose in 1997 as result of the emerging approaches to increase the confidence in the Safety Assessment (SA) considering multiple lines of reasoning show in: some international documents and some national regulation. After a first preliminary (1997-1998) study, the CSN noticed the large amount and dispersion of the information about NNA, and decided to launch a deeper Study with the aims of: Collecting and reviewing the results of all the relevant studies on analogues developed in the last decades in systematic way; Reaching a better understanding of their potential and real application to the SA and for communication purposes. The results of the Analogue Study has been structured in several documents with different levels of detail and technical content addressed to different audiences. Analogue studies are a source of knowledge for the understanding of the long-term behavior of DGD systems. They represent a complementary method to increase Confidence Building within PA. In the majority of the cases, analogues have been used to transmit information on generic aspects of the geological concept an easily understood message. The need to simplify the content to facilitate their understanding may imply different information to different audiences. Analogue studies are: Considered within the multiple lines of reasoning to increase the confidence in the SA; A source of knowledge for the understanding of the long-term behavior of DGD systems. They represent a complementary method to increase Confidence Building within SA. There are few examples of the direct use of data from natural analogue projects in the consulted SA. They are promoted by International organisations

THE PENA BLANCA NATURAL ANALOGUE PERFORMANCE ASSESSMENT MODEL

Energy Technology Data Exchange (ETDEWEB)

G.J. Saulnier Jr; W. Statham

2006-03-10

The Nopal I uranium mine in the Sierra Pena Blanca, Chihuahua, Mexico serves as a natural analogue to the Yucca Mountain repository. The Pena Blanca Natural Analogue Performance Assessment Model simulates the mobilization and transport of radionuclides that are released from the mine and transported to the saturated zone. the Pena Blanca Natural Analogue Model uses probabilistic simulations of hydrogeologic processes that are analogous to the processes that occur at the Yucca Mountain site. The Nopal I uranium deposit lies in fractured, welded, and altered rhyolitic ash flow tuffs that overlie carbonate rocks, a setting analogous to the geologic formations at the Yucca Mountain site. The Nopal I mine site has the following characteristics as compared to the Yucca Mountain repository site. (1) Analogous source: UO{sub 2} uranium ore deposit = spent nuclear fuel in the repository; (2) Analogous geologic setting: fractured, welded, and altered rhyolitic ash flow tuffs overlying carbonate rocks; (3) Analogous climate: Semiarid to arid; (4) Analogous geochemistry: Oxidizing conditions; and (5) Analogous hydrogeology: The ore deposit lies in the unsaturated zone above the water table. The Nopal I deposit is approximately 8 {+-} 0.5 million years old and has been exposed to oxidizing conditions during the last 3.2 to 3.4 million years. The Pena Blanca Natural Analogue Model considers that the uranium oxide and uranium silicates in the ore deposit were originally analogous to uranium-oxide spent nuclear fuel. The Pena Blanca site has been characterized using field and laboratory investigations of its fault and fracture distribution, mineralogy, fracture fillings, seepage into the mine adits, regional hydrology, and mineralization that shows the extent of radionuclide migration. Three boreholes were drilled at the Nopal I mine site in 2003 and these boreholes have provided samples for lithologic characterization, water-level measurements, and water samples for laboratory

THE PENA BLANCA NATURAL ANALOGUE PERFORMANCE ASSESSMENT MODEL

International Nuclear Information System (INIS)

G.J. Saulnier Jr; W. Statham

2006-01-01

The Nopal I uranium mine in the Sierra Pena Blanca, Chihuahua, Mexico serves as a natural analogue to the Yucca Mountain repository. The Pena Blanca Natural Analogue Performance Assessment Model simulates the mobilization and transport of radionuclides that are released from the mine and transported to the saturated zone. the Pena Blanca Natural Analogue Model uses probabilistic simulations of hydrogeologic processes that are analogous to the processes that occur at the Yucca Mountain site. The Nopal I uranium deposit lies in fractured, welded, and altered rhyolitic ash flow tuffs that overlie carbonate rocks, a setting analogous to the geologic formations at the Yucca Mountain site. The Nopal I mine site has the following characteristics as compared to the Yucca Mountain repository site. (1) Analogous source: UO 2 uranium ore deposit = spent nuclear fuel in the repository; (2) Analogous geologic setting: fractured, welded, and altered rhyolitic ash flow tuffs overlying carbonate rocks; (3) Analogous climate: Semiarid to arid; (4) Analogous geochemistry: Oxidizing conditions; and (5) Analogous hydrogeology: The ore deposit lies in the unsaturated zone above the water table. The Nopal I deposit is approximately 8 ± 0.5 million years old and has been exposed to oxidizing conditions during the last 3.2 to 3.4 million years. The Pena Blanca Natural Analogue Model considers that the uranium oxide and uranium silicates in the ore deposit were originally analogous to uranium-oxide spent nuclear fuel. The Pena Blanca site has been characterized using field and laboratory investigations of its fault and fracture distribution, mineralogy, fracture fillings, seepage into the mine adits, regional hydrology, and mineralization that shows the extent of radionuclide migration. Three boreholes were drilled at the Nopal I mine site in 2003 and these boreholes have provided samples for lithologic characterization, water-level measurements, and water samples for laboratory analysis

Space use and territoriality in swift foxes (Vulpes velox) in northeastern Colorado

DEFF Research Database (Denmark)

Lebsock, Amariah A.; Burdett, Christopher L.; Darden, Safi K.

2012-01-01

Space use is a fundamental characteristic that informs our knowledge of social relationships and the degree to which individuals are territorial. Until recently, relatively little was known about the spatial ecology and social organization of swift foxes (Vulpes velox (Say, 1823)). We investigated...

Dynamics of continuous-time bidirectional associative memory neural networks with impulses and their discrete counterparts

International Nuclear Information System (INIS)

Huo Haifeng; Li Wantong

2009-01-01

This paper is concerned with the global stability characteristics of a system of equations modelling the dynamics of continuous-time bidirectional associative memory neural networks with impulses. Sufficient conditions which guarantee the existence of a unique equilibrium and its exponential stability of the networks are obtained. For the goal of computation, discrete-time analogues of the corresponding continuous-time bidirectional associative memory neural networks with impulses are also formulated and studied. Our results show that the above continuous-time and discrete-time systems with impulses preserve the dynamics of the networks without impulses when we make some modifications and impose some additional conditions on the systems, the convergence characteristics dynamics of the networks are preserved by both continuous-time and discrete-time systems with some restriction imposed on the impulse effect.

Accumulation of radium in relation to some chemical analogues in Dicranopteris linearis

International Nuclear Information System (INIS)

Chao, J.H.; Chuang, C.Y.

2011-01-01

This study elucidates the uptake and accumulation of radium in the field-growing fern Dicranopteris linearis by relating the radium concentration to some potential chemical analogues, including alkaline earth metals, rare earth elements, and some important heavy metals. Time-dependent accumulation of radium and these chemical analogues for D. linearis were described by the 228 Th/ 228 Ra activity ratio, an index for inferring plant age. The correlation between radium and these elements was assessed by statistical analysis and used as a reference to elucidate the uptake and accumulation of radium in relation to the chemical analogues. Analytical and statistical results showed that the concentrations of alkaline earth metals (except for Mg) rare earth elements and some heavy metals in D. linearis increased linearly with plant age. These elements, exhibiting a similar accumulation pattern to radium and significant correlation coefficients with radium, were considered as the chemical analogues to radium. Additionally, the plant/soil concentration ratios (CRs) for radium and most of these analogues in D. linearis exceeded 1, consistent with the definition of hyper-accumulator plants.

Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid

Directory of Open Access Journals (Sweden)

Patrick Rabe

2014-08-01

Full Text Available Tropodithietic acid (TDA is a structurally unique sulfur-containing antibiotic from the Roseobacter clade bacterium Phaeobacter inhibens DSM 17395 and a few other related species. We have synthesised several structural analogues of TDA and used them in bioactivity tests against Staphylococcus aureus and Vibrio anguillarum for a structure–activity relationship (SAR study, revealing that the sulfur-free analogue of TDA, tropone-2-carboxylic acid, has an antibiotic activity that is even stronger than the bioactivity of the natural product. The synthesis of this compound and of several analogues is presented and the bioactivity of the synthetic compounds is discussed.

Somatostatin analogues labelled with 99mTc

International Nuclear Information System (INIS)

Obenaus, Esteban R.; Crudo, Jose L.; Edreira, Martin M.; Castiglia, Silvia G.

1999-01-01

Biological and radiochemical studies have been carried out on two labelled somatostatin analogues, the peptide RC-150 and the Tyr 3 -Octreotide. Both analogues have been labelled with 99m Tc using the direct and the indirect method and MAG-3 and HYNIC as chelating agents. By the direct method RC-150 was labelled using sodium ascorbate and dithionite as reducing agents. The radiochemical purity was 70%. By the indirect method, in the case of RC-160 with MAG-3 a radiochemical purity higher than 70% was attained while a purity of 100% was reached in the case of Tyr 3 -Octreotide with HYNIC. The biological distribution of HYNIC-Tyr 3 -Octreotide has been studied in rats. (author)

Boron hydride analogues of the fullerenes

International Nuclear Information System (INIS)

Quong, A.A.; Pederson, M.R.; Broughton, J.Q.

1994-01-01

The BH moiety is isoelectronic with C. We have studied the stability of the (BH) 60 analogue of the C 60 fullerene as well as the dual-structure (BH) 32 icosahedron, both of them being putative structures, by performing local-density-functional electronic calculations. To aid in our analysis, we have also studied other homologues of these systems. We find that the latter, i.e., the dual structure, is the more stable although the former is as stable as one of the latter's lower homologues. Boron hydrides, it seems, naturally form the dual structures used in algorithmic optimization of complex fullerene systems. Fully relaxed geometries are reported as well as electron affinities and effective Hubbard U parameters. These systems form very stable anions and we conclude that a search for BH analogues of the C 60 alkali-metal supeconductors might prove very fruitful

Swift heavy ion induced surface and microstructural evolution in metallic glass thin films

International Nuclear Information System (INIS)

Thomas, Hysen; Thomas, Senoy; Ramanujan, Raju V.; Avasthi, D.K.; Al- Omari, I.A.; Al-Harthi, Salim; Anantharaman, M.R.

2012-01-01

Swift heavy ion induced changes in microstructure and surface morphology of vapor deposited Fe–Ni based metallic glass thin films have been investigated by using atomic force microscopy, X-ray diffraction and transmission electron microscopy. Ion beam irradiation was carried out at room temperature with 103 MeV Au 9+ beam with fluences ranging from 3 × 10 11 to 3 × 10 13 ions/cm 2 . The atomic force microscopy images were subjected to power spectral density analysis and roughness analysis using an image analysis software. Clusters were found in the image of as-deposited samples, which indicates that the film growth is dominated by the island growth mode. As-deposited films were amorphous as evidenced from X-ray diffraction; however, high resolution transmission electron microscopy measurements revealed a short range atomic order in the samples with crystallites of size around 3 nm embedded in an amorphous matrix. X-ray diffraction pattern of the as-deposited films after irradiation does not show any appreciable changes, indicating that the passage of swift heavy ions stabilizes the short range atomic ordering, or even creates further amorphization. The crystallinity of the as-deposited Fe–Ni based films was improved by thermal annealing, and diffraction results indicated that ion beam irradiation on annealed samples results in grain fragmentation. On bombarding annealed films, the surface roughness of the films decreased initially, then, at higher fluences it increased. The observed change in surface morphology of the irradiated films is attributed to the interplay between ion induced sputtering, volume diffusion and surface diffusion.

A numerical investigation into the performance of the soil nail wall and pile foundation at the Swift Delta I-5 Interchange.

Science.gov (United States)

1993-12-01

Finite Difference Methods (FDM) and Finite Element Methods (FEM) studies are reported studying the soil nail wall construction at the Swift Delta I-5 Interchange bridge reconstruction in North Portland, Oregon. Five layers of soil nails were installe...

Thymidine analogue-sparing highly active antiretroviral therapy (HAART).

Science.gov (United States)

Nolan, David; Mallal, Simon

2003-02-01

The use of alternative nucleoside reverse transcriptase inhibitors (NRTIs) to the thymidine analogues stavudine (d4T) and zidovudine(ZDV) has been advocated as a means of limiting long-term NRTI-associated toxicity, particularly the development of lipoatrophy or fat wasting. This approach reflects an increasing knowledge of the distinct toxicity profiles of NRTI drugs. However, recent clinical trials have demonstrated that the use of thymidine analogue NRTIs and newer alternative backbone NRTIs, such as tenofovir (TNF) and abacavir (ABC), is associated with comparable short-term efficacy and tolerability. Given the importance of toxicity profile differences in determining clinical management, it is important to recognise that d4T and ZDV cary significantly different risks for long-term NRTI toxicity. Recognising that all NRTIs, including thymidine analogues, have individual toxicity profiles provides a more appropriate basis for selecting optimal antiretroviral therapy. The safety and efficacy of TNF and ABC are also reviewed here, although the available data provide only limited knowledge of the long-term effects of these drugs in terms of toxicity and antiviral durability.

Raman investigation of lattice defects and stress induced in InP and GaN films by swift heavy ion irradiation

Energy Technology Data Exchange (ETDEWEB)

Hu, P.P. [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China); University of Chinese Academy of Sciences (UCAS), Beijing 100049 (China); Liu, J., E-mail: J.Liu@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China); Zhang, S.X. [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China); University of Chinese Academy of Sciences (UCAS), Beijing 100049 (China); Maaz, K. [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China); Nanomaterials Research Group, Physics Division, PINSTECH, Nilore, 45650 Islamabad (Pakistan); Zeng, J. [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China); Guo, H. [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China); University of Chinese Academy of Sciences (UCAS), Beijing 100049 (China); Zhai, P.F.; Duan, J.L.; Sun, Y.M.; Hou, M.D. [Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000 (China)

2016-04-01

InP crystals and GaN films were irradiated by swift heavy ions {sup 86}Kr and {sup 209}Bi with kinetic energies of 25 and 9.5 MeV per nucleon and ion fluence in the range 5 × 10{sup 10} to 3.6 × 10{sup 12} ions/cm{sup 2}. The characteristic optical bands were studied by Raman spectroscopy to reveal the disorder and defects induced in the samples during the irradiation process. The crystallinity of InP and GaN was found to be deteriorated after irradiation by the swift heavy ions and resulted in the amorphous nature of the samples along the ion tracks. The amorphous tracks observed by transmission electron microscopy (TEM) images confirmed the formation of lattice defects. In typical F{sub 2}(LO) mode, in case of InP, the spectra shifted towards the lower wavenumbers with a maximum shift of 7.6 cm{sup −1} induced by 1030 MeV Bi ion irradiation. While in case of GaN, the typical E{sub 2}(high) mode shifted towards the higher wavenumbers, with maximum shift of 5.4 cm{sup −1} induced by 760 MeV Bi ion irradiation at ion fluence of 1 × 10{sup 12} ions/cm{sup 2}. The observed Raman shifts reveal the presence of lattice defects and disorder induced in the samples after irradiation by the swift heavy ions. This irradiation also generated lattice stress in the samples, which has been investigated and discussed in detail in this work.

In vitro and in vivo potency of insulin analogues designed for clinical use.

Science.gov (United States)

Vølund, A; Brange, J; Drejer, K; Jensen, I; Markussen, J; Ribel, U; Sørensen, A R; Schlichtkrull, J

1991-11-01

Analogues of human insulin designed to have improved absorption properties after subcutaneous injection have been prepared by recombinant DNA technology. Five rapidly absorbed analogues, being predominantly in mono- or di-meric states in the pharmaceutical preparation, and a hexameric analogue with very low solubility at neutral pH and slow absorption, were studied. Receptor binding assays with HEP-G2 cells showed overall agreement with mouse free adipocyte assays. Two analogues, B28Asp and A21Gly + B27Arg + B30Thr-NH2, had nearly the same molar in vitro potency as human insulin. Another two showed increased adipocyte potency and receptor binding, B10Asp 194% and 333% and A8His + B4His + B10Glu + B27His 575% and 511%, while B9Asp + B27Glu showed 29% and 18% and the B25Asp analogue only 0.12% and 0.05% potency. Bioassays in mice or rabbits of the analogues except B25Asp showed that they had the same in vivo potency as human insulin 1.00 IU = 6.00 nmol. Thus the variation had the same in vivo potency as human insulin 1.00 IU = 6.00 nmol. Thus the variation in in vivo potency reflects the differences in receptor binding affinity. Relative to human insulin a low concentration is sufficient for a high affinity analogue to produce a given receptor complex formation and metabolic response. In conclusion, human insulin and analogues with markedly different in vitro potencies were equipotent in terms of hypoglycaemic effect. This is in agreement with the concept that elimination of insulin from blood and its subsequent degradation is mediated by insulin receptors.

Prussian Blue Analogues of Reduced Dimensionality

NARCIS (Netherlands)

Gengler, Regis Y. N.; Toma, Luminita M.; Pardo, Emilio; Lloret, Francesc; Ke, Xiaoxing; Van Tendeloo, Gustaaf; Gournis, Dimitrios; Rudolf, Petra

2012-01-01

Mixed-valence polycyanides (Prussian Blue analogues) possess a rich palette of properties spanning from room-temperature ferromagnetism to zero thermal expansion, which can be tuned by chemical modifications or the application of external stimuli (temperature, pressure, light irradiation). While

Charge-state related effects in sputtering of LiF by swift heavy ions

Energy Technology Data Exchange (ETDEWEB)

Assmann, W. [Ludwig-Maximilians-Universität München, 85748 Garching (Germany); Ban-d' Etat, B. [Centre de Recherche sur les Ions, les Matériaux et la photonique, CIMAP-GANIL, CEA–CNRS–ENSICAEN–Univ. Caen, 14070 Caen (France); Bender, M. [GSI Helmholtzzentrum für Schwerionenforschung, 64291 Darmstadt (Germany); Boduch, P. [Centre de Recherche sur les Ions, les Matériaux et la photonique, CIMAP-GANIL, CEA–CNRS–ENSICAEN–Univ. Caen, 14070 Caen (France); Grande, P.L. [Univ. Fed. Rio Grande do Sul, BR-91501970 Porto Alegre, RS (Brazil); Lebius, H.; Lelièvre, D. [Centre de Recherche sur les Ions, les Matériaux et la photonique, CIMAP-GANIL, CEA–CNRS–ENSICAEN–Univ. Caen, 14070 Caen (France); Marmitt, G.G. [Univ. Fed. Rio Grande do Sul, BR-91501970 Porto Alegre, RS (Brazil); Rothard, H. [Centre de Recherche sur les Ions, les Matériaux et la photonique, CIMAP-GANIL, CEA–CNRS–ENSICAEN–Univ. Caen, 14070 Caen (France); Seidl, T.; Severin, D.; Voss, K.-O. [GSI Helmholtzzentrum für Schwerionenforschung, 64291 Darmstadt (Germany); Toulemonde, M., E-mail: toulemonde@ganil.fr [Centre de Recherche sur les Ions, les Matériaux et la photonique, CIMAP-GANIL, CEA–CNRS–ENSICAEN–Univ. Caen, 14070 Caen (France); Trautmann, C. [GSI Helmholtzzentrum für Schwerionenforschung, 64291 Darmstadt (Germany); Technische Universität Darmstadt, 64289 Darmstadt (Germany)

2017-02-01

Sputtering experiments with swift heavy ions in the electronic energy loss regime were performed by using the catcher technique in combination with elastic recoil detection analysis. The angular distribution of particles sputtered from the surface of LiF single crystals is composed of a jet-like peak superimposed on a broad isotropic distribution. By using incident ions of fixed energy but different charges states, the influence of the electronic energy loss on both components is probed. We find indications that isotropic sputtering originates from near-surface layers, whereas the jet component may be affected by contributions from depth up to about 150 nm.

Receptor-isoform-selective insulin analogues give tissue-preferential effects

DEFF Research Database (Denmark)

Vienberg, Sara Gry; Bouman, Stephan D; Sørensen, Heidi

2011-01-01

The relative expression patterns of the two IR (insulin receptor) isoforms, +/- exon 11 (IR-B/IR-A respectively), are tissue-dependent. Therefore we have developed insulin analogues with different binding affinities for the two isoforms to test whether tissue-preferential biological effects can...... be attained. In rats and mice, IR-B is the most prominent isoform in the liver (> 95%) and fat (> 90%), whereas in muscles IR-A is the dominant isoform (> 95%). As a consequence, the insulin analogue INS-A, which has a higher relative affinity for human IR-A, had a higher relative potency [compared with HI...... (human insulin)] for glycogen synthesis in rat muscle strips (26%) than for glycogen accumulation in rat hepatocytes (5%) and for lipogenesis in rat adipocytes (4%). In contrast, the INS-B analogue, which has an increased affinity for human IR-B, had higher relative potencies (compared with HI...

Intelligent Memory Module Overcomes Harsh Environments

Science.gov (United States)

2008-01-01

Solar cells, integrated circuits, and sensors are essential to manned and unmanned space flight and exploration, but such systems are highly susceptible to damage from radiation. Especially problematic, the Van Allen radiation belts encircle Earth in concentric radioactive tori at distances from about 6,300 to 38,000 km, though the inner radiation belt can dip as low as 700 km, posing a severe hazard to craft and humans leaving Earth s atmosphere. To avoid this radiation, the International Space Station and space shuttles orbit at altitudes between 275 and 460 km, below the belts range, and Apollo astronauts skirted the edge of the belts to minimize exposure, passing swiftly through thinner sections of the belts and thereby avoiding significant side effects. This radiation can, however, prove detrimental to improperly protected electronics on satellites that spend the majority of their service life in the harsh environment of the belts. Compact, high-performance electronics that can withstand extreme environmental and radiation stress are thus critical to future space missions. Increasing miniaturization of electronics addresses the need for lighter weight in launch payloads, as launch costs put weight at a premium. Likewise, improved memory technologies have reduced size, cost, mass, power demand, and system complexity, and improved high-bandwidth communication to meet the data volume needs of the next-generation high-resolution sensors. This very miniaturization, however, has exacerbated system susceptibility to radiation, as the charge of ions may meet or exceed that of circuitry, overwhelming the circuit and disrupting operation of a satellite. The Hubble Space Telescope, for example, must turn off its sensors when passing through intense radiation to maintain reliable operation. To address the need for improved data quality, additional capacity for raw and processed data, ever-increasing resolution, and radiation tolerance, NASA spurred the development of the

The Valles natural analogue project

International Nuclear Information System (INIS)

Stockman, H.; Krumhansl, J.; Ho, C.; McConnell, V.

1994-12-01

The contact between an obsidian flow and a steep-walled tuff canyon was examined as an analogue for a highlevel waste repository. The analogue site is located in the Valles Caldera in New Mexico, where a massive obsidian flow filled a paleocanyon in the Battleship Rock tuff. The obsidian flow provided a heat source, analogous to waste panels or an igneous intrusion in a repository, and caused evaporation and migration of water. The tuff and obsidian samples were analyzed for major and trace elements and mineralogy by INAA, XRF, X-ray diffraction; and scanning electron microscopy and electron microprobe. Samples were also analyzed for D/H and 39 Ar/ 4O isotopic composition. Overall,the effects of the heating event seem to have been slight and limited to the tuff nearest the contact. There is some evidence of devitrification and migration of volatiles in the tuff within 10 meters of the contact, but variations in major and trace element chemistry are small and difficult to distinguish from the natural (pre-heating) variability of the rocks

Effects of swift heavy ion irradiation on the electrical characteristics of Au/n-GaAs Schottky diodes

International Nuclear Information System (INIS)

Sharma, A. Tarun; Shahnawaz; Kumar, Sandeep; Katharria, Yashpal S.; Kanjilal, Dinakar

2007-01-01

Metal-semiconductor diode of Au/n-GaAs is studied under the irradiation of swift heavy ion (SHI) beam (80 MeV 16 O 6+ ), using in situ current-voltage characterization technique. The diode parameters like ideality factor, barrier height, and leakage current are observed to vary with irradiation fluence. Significantly, the diode performance improves at a high fluence of 2 x 10 13 ions cm -2 with a large decrease of reverse leakage current in comparison to the original as deposited sample. The Schottky barrier height (SBH) also increases with fluence. At a high irradiation fluence of 5 x 10 13 ions cm -2 the SBH (0.62 ± 0.01 eV) is much larger than that of the as deposited sample (0.55 ± 0.01 eV). The diode parameters remain stable over a large range of irradiation up to fluence of 8 x 10 13 ions cm -2 . A prominent annealing effect of the swift ion beam owing to moderate electronic excitation and high ratio of electronic energy loss to the nuclear loss is found to be responsible for the improvement in diode characteristics

Recurrent nova M31N 2008-12a: The 2017-eruption X-ray turn-off seen by Swift/XRT

Science.gov (United States)

Henze, M.; Darnley, M. J.; Shafter, A. W.; Kafka, S.; Kato, M.; Williams, S. C.; et al.

2018-01-01

The detection of supersoft X-ray source (SSS) emission from the 2017 eruption (ATel #11116) of the rapidly recurring nova M31N 2008-12a (Henze et al. 2014, 2015a, 2015b; Darnley et al. 2014, 2015, 2016) with the Neil Gehrels Swift observatory was announced in ATel #11130.

Aspartame and Its Analogues

Science.gov (United States)

Pavlova, L. A.; Komarova, T. V.; Davidovich, Yurii A.; Rogozhin, S. V.

1981-04-01

The results of studies on the biochemistry of the sweet taste are briefly reviewed. The methods of synthesis of "aspartame" — a sweet dipeptide — are considered, its structural analogues are described, and quantitative estimates are made of the degree of sweetness relative to sucrose. Attention is concentrated mainly on problems of the relation between the structure of the substance and its taste in the series of aspartyl derivatives. The bibliography includes 118 references.

Analogue studies at the french atomic commission (CEA)

International Nuclear Information System (INIS)

Petit, J.C.

1986-06-01

The different research activities of the French Atomic Energy Commission in the analogue study field are presented. Most of them are conducted in collaboration with major research organisations, both french and international. In fact, the scientific community has been associated to these programmes at different steps of their realisation. The brief description presented illustrates the great diversity and complementarity of actions conducted by CEA for better understanding, through the study of natural analogues, the basic processes that will rule the long term behaviour of high level radwaste materials in a repository and hence contributing to hopefully guaranty disposal safety

Galaxy Clusters in the Swift/BAT era II: 10 more Clusters detected above 15 keV

Energy Technology Data Exchange (ETDEWEB)

Ajello, M.; /SLAC /KIPAC, Menlo Park; Rebusco, P.; /KIPAC, Menlo Park; Cappelluti, N.; /Garching, Max Planck Inst., MPE /Maryland U., Baltimore County; Reimer, O.; /SLAC /Palermo Observ.; Boehringer, H.; /Garching, Max Planck Inst., MPE; La Parola, V.; Cusumano, G.; /Palermo Observ.

2010-10-27

We report on the discovery of 10 additional galaxy clusters detected in the ongoing Swift/BAT all-sky survey. Among the newly BAT-discovered clusters there are: Bullet, Abell 85, Norma, and PKS 0745-19. Norma is the only cluster, among those presented here, which is resolved by BAT. For all the clusters we perform a detailed spectral analysis using XMM-Newton and Swift/BAT data to investigate the presence of a hard (non-thermal) X-ray excess. We find that in most cases the clusters emission in the 0.3-200 keV band can be explained by a multi-temperature thermal model confirming our previous results. For two clusters (Bullet and Abell 3667) we find evidence for the presence of a hard X-ray excess. In the case of the Bullet cluster, our analysis confirms the presence of a non-thermal, power-law like, component with a 20-100 keV flux of 3.4 x 10{sup -12} erg cm{sup -2} s{sup -1} as detected in previous studies. For Abell 3667 the excess emission can be successfully modeled as a hot component (kT = {approx}13 keV). We thus conclude that the hard X-ray emission from galaxy clusters (except the Bullet) has most likely thermal origin.

GALAXY CLUSTERS IN THE SWIFT/BAT ERA. II. 10 MORE CLUSTERS DETECTED ABOVE 15 keV

International Nuclear Information System (INIS)

Ajello, M.; Reimer, O.; Rebusco, P.; Cappelluti, N.; Boehringer, H.; La Parola, V.; Cusumano, G.

2010-01-01

We report on the discovery of 10 additional galaxy clusters detected in the ongoing Swift/Burst Alert Telescope (BAT) all-sky survey. Among the newly BAT-discovered clusters there are Bullet, A85, Norma, and PKS 0745-19. Norma is the only cluster, among those presented here, which is resolved by BAT. For all the clusters, we perform a detailed spectral analysis using XMM-Newton and Swift/BAT data to investigate the presence of a hard (non-thermal) X-ray excess. We find that in most cases the clusters' emission in the 0.3-200 keV band can be explained by a multi-temperature thermal model confirming our previous results. For two clusters (Bullet and A3667), we find evidence for the presence of a hard X-ray excess. In the case of the Bullet cluster, our analysis confirms the presence of a non-thermal, power-law-like, component with a 20-100 keV flux of 3.4 x 10 -12 erg cm -2 s -1 as detected in previous studies. For A3667, the excess emission can be successfully modeled as a hot component (kT ∼ 13 keV). We thus conclude that the hard X-ray emission from galaxy clusters (except the Bullet) has most likely a thermal origin.

Trehalose Analogues: Latest Insights in Properties and Biocatalytic Production

Directory of Open Access Journals (Sweden)

Maarten Walmagh

2015-06-01

Full Text Available Trehalose (α-d-glucopyranosyl α-d-glucopyranoside is a non-reducing sugar with unique stabilizing properties due to its symmetrical, low energy structure consisting of two 1,1-anomerically bound glucose moieties. Many applications of this beneficial sugar have been reported in the novel food (nutricals, medical, pharmaceutical and cosmetic industries. Trehalose analogues, like lactotrehalose (α-d-glucopyranosyl α-d-galactopyranoside or galactotrehalose (α-d-galactopyranosyl α-d-galactopyranoside, offer similar benefits as trehalose, but show additional features such as prebiotic or low-calorie sweetener due to their resistance against hydrolysis during digestion. Unfortunately, large-scale chemical production processes for trehalose analogues are not readily available at the moment due to the lack of efficient synthesis methods. Most of the procedures reported in literature suffer from low yields, elevated costs and are far from environmentally friendly. “Greener” alternatives found in the biocatalysis field, including galactosidases, trehalose phosphorylases and TreT-type trehalose synthases are suggested as primary candidates for trehalose analogue production instead. Significant progress has been made in the last decade to turn these into highly efficient biocatalysts and to broaden the variety of useful donor and acceptor sugars. In this review, we aim to provide an overview of the latest insights and future perspectives in trehalose analogue chemistry, applications and production pathways with emphasis on biocatalysis.

Superconductive analogue of spin glasses

International Nuclear Information System (INIS)

Feigel'man, M.; Ioffe, L.; Vinokur, V.; Larkin, A.

1987-07-01

The properties of granular superconductors in magnetic fields, namely the existence of a new superconductive state analogue of the low-temperature superconductive state in spin glasses are discussed in the frame of the infinite-range model and the finite-range models. Experiments for elucidation of spin-glass superconductive state in real systems are suggested. 30 refs

Neurochemical binding profiles of novel indole and benzofuran MDMA analogues.

Science.gov (United States)

Shimshoni, Jakob A; Winkler, Ilan; Golan, Ezekiel; Nutt, David

2017-01-01

3,4-Methylenedioxy-N-methylamphetamine (MDMA) has been shown to be effective in the treatment of post-traumatic stress disorder (PTSD) in numerous clinical trials. In the present study, we have characterized the neurochemical binding profiles of three MDMA-benzofuran analogues (1-(benzofuran-5-yl)-propan-2-amine, 5-APB; 1-(benzofuran-6-yl)-N-methylpropan-2-amine, 6-MAPB; 1-(benzofuran-5-yl)-N-methylpropan-2-amine, 5-MAPB) and one MDMA-indole analogue (1-(1H-indol-5-yl)-2-methylamino-propan-1-ol, 5-IT). These compounds were screened as potential second-generation anti-PTSD drugs, against a battery of human and non-human receptors, transporters, and enzymes, and their potencies as 5-HT 2 receptor agonist and monoamine uptake inhibitors determined. All MDMA analogues displayed high binding affinities for 5-HT 2a,b,c and NE α2 receptors, as well as significant 5-HT, DA, and NE uptake inhibition. 5-APB revealed significant agonist activity at the 5-HT 2a,b,c receptors, while 6-MAPB, 5-MAPB, and 5-IT exhibited significant agonist activity at the 5-HT 2c receptor. There was a lack of correlation between the results of functional uptake and the monoamine transporter binding assay. MDMA analogues emerged as potent and selective monoamine oxidase A inhibitors. Based on 6-MAPB favorable pharmacological profile, it was further subjected to IC 50 determination for monoamine transporters. Overall, all MDMA analogues displayed higher monoamine receptor/transporter binding affinities and agonist activity at the 5-HT 2a,c receptors as compared to MDMA.

The Algebra of a q-Analogue of Multiple Harmonic Series

Directory of Open Access Journals (Sweden)

Yoshihiro Takeyama

2013-10-01

Full Text Available We introduce an algebra which describes the multiplication structure of a family of q-series containing a q-analogue of multiple zeta values. The double shuffle relations are formulated in our framework. They contain a q-analogue of Hoffman's identity for multiple zeta values. We also discuss the dimension of the space spanned by the linear relations realized in our algebra.

Naturally occurring crystalline phases: analogues for radioactive waste forms

International Nuclear Information System (INIS)

Haaker, R.F.; Ewing, R.C.

1981-01-01

Naturally occurring mineral analogues to crystalline phases that are constituents of crystalline radioactive waste forms provide a basis for comparison by which the long-term stability of these phases may be estimated. The crystal structures and the crystal chemistry of the following natural analogues are presented: baddeleyite, hematite, nepheline; pollucite, scheelite;sodalite, spinel, apatite, monazite, uraninite, hollandite-priderite, perovskite, and zirconolite. For each phase in geochemistry, occurrence, alteration and radiation effects are described. A selected bibliography for each phase is included

Naturally occurring crystalline phases: analogues for radioactive waste forms

Energy Technology Data Exchange (ETDEWEB)

Haaker, R.F.; Ewing, R.C.

1981-01-01

Naturally occurring mineral analogues to crystalline phases that are constituents of crystalline radioactive waste forms provide a basis for comparison by which the long-term stability of these phases may be estimated. The crystal structures and the crystal chemistry of the following natural analogues are presented: baddeleyite, hematite, nepheline; pollucite, scheelite;sodalite, spinel, apatite, monazite, uraninite, hollandite-priderite, perovskite, and zirconolite. For each phase in geochemistry, occurrence, alteration and radiation effects are described. A selected bibliography for each phase is included.

Design, Synthesis and Cytotoxic Evaluation of o-Carboxamido Stilbene Analogues

Directory of Open Access Journals (Sweden)

Mohamad Nurul Azmi

2013-11-01

Full Text Available Resveratrol, a natural stilbene found in grapes and wines exhibits a wide range of pharmacological properties. Resveratrol is also known as a good chemopreventive agent for inhibiting carcinogenesis processes that target kinases, cyclooxygenases, ribonucleotide reductase and DNA polymerases. A total of 19 analogues with an amide moiety were synthesized and the cytotoxic effects of the analogues on a series of human cancer cell lines are reported. Three compounds 6d, 6i and 6n showed potent cytotoxicity against prostate cancer DU-145 (IC50 = 16.68 µM, colon cancer HT-29 (IC50 = 7.51 µM and breast cancer MCF-7 (IC50 = 21.24 µM, respectively, which are comparable with vinblastine. The resveratrol analogues were synthesized using the Heck method.

Swift heavy ion irradiation effects in Pt/C and Ni/C multilayers

Science.gov (United States)

Gupta, Ajay; Pandita, Suneel; Avasthi, D. K.; Lodha, G. S.; Nandedkar, R. V.

1998-12-01

Irradiation effects of 100 MeV Ag ion irradiation on Ni/C and Pt/C multilayers have been studied using X-ray reflectivity measurements. Modifications are observed in both the multilayers at (dE/dx)e values much below the threshold values for Ni and Pt. This effect is attributed to the discontinuous nature of the metal layers. In both the multilayers interfacial roughness increases with irradiation dose. While Ni/C multilayers exhibit large ion-beam induced intermixing, no observable intermixing is observed in the case of Pt/C multilayer. This difference in the behavior of the two systems suggests a significant role for chemically guided defect motion in the mixing process associated with swift heavy ion irradiation.

A thesis on the Development of an Automated SWIFT Edge Detection Algorithm

Energy Technology Data Exchange (ETDEWEB)

Trujillo, Christopher J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-07-28

Throughout the world, scientists and engineers such as those at Los Alamos National Laboratory, perform research and testing unique only to applications aimed towards advancing technology, and understanding the nature of materials. With this testing, comes a need for advanced methods of data acquisition and most importantly, a means of analyzing and extracting the necessary information from such acquired data. In this thesis, I aim to produce an automated method implementing advanced image processing techniques and tools to analyze SWIFT image datasets for Detonator Technology at Los Alamos National Laboratory. Such an effective method for edge detection and point extraction can prove to be advantageous in analyzing such unique datasets and provide for consistency in producing results.

THE PENA BLANCA NATURAL ANALOGUE PERFORMANCE ASSESSMENT MODEL

Energy Technology Data Exchange (ETDEWEB)

G. Saulnier and W. Statham

2006-04-16

The Nopal I uranium mine in the Sierra Pena Blanca, Chihuahua, Mexico serves as a natural analogue to the Yucca Mountain repository. The Pena Blanca Natural Analogue Performance Assessment Model simulates the mobilization and transport of radionuclides that are released from the mine and transported to the saturated zone. The Pena Blanca Natural Analogue Performance Assessment Model uses probabilistic simulations of hydrogeologic processes that are analogous to the processes that occur at the Yucca Mountain site. The Nopal I uranium deposit lies in fractured, welded, and altered rhyolitic ash-flow tuffs that overlie carbonate rocks, a setting analogous to the geologic formations at the Yucca Mountain site. The Nopal I mine site has the following analogous characteristics as compared to the Yucca Mountain repository site: (1) Analogous source--UO{sub 2} uranium ore deposit = spent nuclear fuel in the repository; (2) Analogous geology--(i.e. fractured, welded, and altered rhyolitic ash-flow tuffs); (3) Analogous climate--Semiarid to arid; (4) Analogous setting--Volcanic tuffs overlie carbonate rocks; and (5) Analogous geochemistry--Oxidizing conditions Analogous hydrogeology: The ore deposit lies in the unsaturated zone above the water table.

THE PENA BLANCA NATURAL ANALOGUE PERFORMANCE ASSESSMENT MODEL

International Nuclear Information System (INIS)

G. Saulnier; W. Statham

2006-01-01

The Nopal I uranium mine in the Sierra Pena Blanca, Chihuahua, Mexico serves as a natural analogue to the Yucca Mountain repository. The Pena Blanca Natural Analogue Performance Assessment Model simulates the mobilization and transport of radionuclides that are released from the mine and transported to the saturated zone. The Pena Blanca Natural Analogue Performance Assessment Model uses probabilistic simulations of hydrogeologic processes that are analogous to the processes that occur at the Yucca Mountain site. The Nopal I uranium deposit lies in fractured, welded, and altered rhyolitic ash-flow tuffs that overlie carbonate rocks, a setting analogous to the geologic formations at the Yucca Mountain site. The Nopal I mine site has the following analogous characteristics as compared to the Yucca Mountain repository site: (1) Analogous source--UO 2 uranium ore deposit = spent nuclear fuel in the repository; (2) Analogous geology--(i.e. fractured, welded, and altered rhyolitic ash-flow tuffs); (3) Analogous climate--Semiarid to arid; (4) Analogous setting--Volcanic tuffs overlie carbonate rocks; and (5) Analogous geochemistry--Oxidizing conditions Analogous hydrogeology: The ore deposit lies in the unsaturated zone above the water table

Transdermal delivery of a melanotropic peptide hormone analogue

International Nuclear Information System (INIS)

Dawson, B.V.; Hadley, M.E.; Kreutzfeld, K.; Dorr, R.T.; Hruby, V.J.; Al-Obeidi, F.; Don, S.

1988-01-01

We previously reported that topical application of [Nl3 4 ,D-Phe 7 ]alpha-MSH, a superpotent analogue of alpha-melanocyte stimulating hormone, to mice induces a darkening of follicular melanocytes throughout the skin. We now report that the melanotropin analogue can be delivered across mouse but not rat skin in an in vitro model system. Passage of the analogue from the topically applied vehicle (polyethylene glycol) across the skin into a subcutaneous receiving vessel was demonstrated by both bioassay as well as by radioimmunoassay. The bioassay data demonstrate that percutaneous absorption of the melanotropin did not result in loss of biological activity of the peptide. The differential penetration of the peptide across rodent skin reveals that one cannot predict percutaneous absorption of a substance across the stratum corneum from studies on a single species. The present results are the first to demonstrate, by direct quantitative measurements, that a bioactive peptide can be delivered across the vertebrate integument in vitro. These studies point out the potential of a topically applied melanotropin for tanning of the skin and possibly for treatment of certain hypopigmentary disorders

Manipulating lightcone fluctuations in an analogue cosmic string

Directory of Open Access Journals (Sweden)

Jiawei Hu

2018-02-01

Full Text Available We study the flight time fluctuations in an anisotropic medium inspired by a cosmic string with an effective fluctuating refractive index caused by fluctuating vacuum electric fields, which are analogous to the lightcone fluctuations due to fluctuating spacetime metric when gravity is quantized. The medium can be realized as a metamaterial that mimics a cosmic string in the sense of transformation optics. For a probe light close to the analogue string, the flight time variance is ν times that in a normal homogeneous and isotropic medium, where ν is a parameter characterizing the deficit angle of the spacetime of a cosmic string. The parameter ν, which is always greater than unity for a real cosmic string, is determined by the dielectric properties of the metamaterial for an analogue string. Therefore, the flight time fluctuations of a probe light can be manipulated by changing the electric permittivity and magnetic permeability of the analogue medium. We argue that it seems possible to fabricate a metamaterial that mimics a cosmic string with a large ν in laboratory so that a currently observable flight time variance might be achieved.

Natural analogue studies as supplements to biomineralization research

International Nuclear Information System (INIS)

McNeil, M.B.

1995-01-01

Chemical reactions can alter the chemistry and crystal structure of solid objects over archeological or geological times, while preserving external physical shapes. The reactions resulting in these structures offer natural analogues to laboratory experiments in biomineralization and to biologically influenced alteration of nuclear waste packages, and thus, they offer the only available way of validating models that purport waste package behavior over archaeological or geological times. Potential uses of such analogues in the construction and validation of hypothetical mechanisms of microbiological corrosion and biomineralization are reviewed. Evidence from such analogues suggests that biofilms can control materials alteration in ways usually overlooked. The newly hypothesized mechanisms involve control by biofilms of the cation flow near the solid surface and offer plausible mechanisms for the formation of mixed-cation minerals under conditions that would lead to dealloying in abiotic experiments; they also account for the formation of unusual minerals [such as posnjakite, Cu 4 SO 4 (OH) 6· H 2 O] and mineral morphologies unusual in corrosion [malachite, Cu 2 CO 3 (OH) 2 , rarely forms botryoidally under corrosion conditions and its occasional presence on archaeological objects that appear to have undergone microbiological corrosion may be related to biofilm phenomena

Manipulating lightcone fluctuations in an analogue cosmic string

Science.gov (United States)

Hu, Jiawei; Yu, Hongwei

2018-02-01

We study the flight time fluctuations in an anisotropic medium inspired by a cosmic string with an effective fluctuating refractive index caused by fluctuating vacuum electric fields, which are analogous to the lightcone fluctuations due to fluctuating spacetime metric when gravity is quantized. The medium can be realized as a metamaterial that mimics a cosmic string in the sense of transformation optics. For a probe light close to the analogue string, the flight time variance is ν times that in a normal homogeneous and isotropic medium, where ν is a parameter characterizing the deficit angle of the spacetime of a cosmic string. The parameter ν, which is always greater than unity for a real cosmic string, is determined by the dielectric properties of the metamaterial for an analogue string. Therefore, the flight time fluctuations of a probe light can be manipulated by changing the electric permittivity and magnetic permeability of the analogue medium. We argue that it seems possible to fabricate a metamaterial that mimics a cosmic string with a large ν in laboratory so that a currently observable flight time variance might be achieved.

Optimization of gefitinib analogues with potent anticancer activity.

Science.gov (United States)

Yin, Kai-Hao; Hsieh, Yi-Han; Sulake, Rohidas S; Wang, Su-Pei; Chao, Jui-I; Chen, Chinpiao

2014-11-15

The interactions of gefitinib (Iressa) in EGFR are hydrogen bonding and van der Waals forces through quinazoline and aniline rings. However the morpholino group of gefitinib is poorly ordered due to its weak electron density. A series of novel piperazino analogues of gefitinib where morpholino group substituted with various piperazino groups were designed and synthesized. Most of them indicated significant anti-cancer activities against human cancer cell lines. In particular, compounds 52-54 showed excellent potency against cancer cells. Convergent synthetic approach has been developed for the synthesis of gefitinib intermediate which can lead to gefitinib as well as numerous analogues. Copyright © 2014 Elsevier Ltd. All rights reserved.

FAINT NEAR-ULTRAVIOLET/FAR-ULTRAVIOLET STANDARDS FROM SWIFT/UVOT, GALEX, AND SDSS PHOTOMETRY

International Nuclear Information System (INIS)

Siegel, Michael H.; Hoversten, Erik A.; Roming, Peter W. A.; Brown, Peter

2010-01-01

At present, the precision of deep ultraviolet photometry is somewhat limited by the dearth of faint ultraviolet standard stars. In an effort to improve this situation, we present a uniform catalog of 11 new faint (u ∼ 17) ultraviolet standard stars. High-precision photometry of these stars has been taken from the Sloan Digital Sky Survey and Galaxy Evolution Explorer archives and combined with new data from the Swift Ultraviolet Optical Telescope to provide precise photometric measures extending from the near-infrared to the far-ultraviolet. These stars were chosen because they are known to be hot (20, 000 eff < 50, 000 K) DA white dwarfs with published Sloan spectra that should be photometrically stable. This careful selection allows us to compare the combined photometry and Sloan spectroscopy to models of pure hydrogen atmospheres to both constrain the underlying properties of the white dwarfs and test the ability of white dwarf models to predict the photometric measures. We find that the photometry provides good constraints on white dwarf temperatures, which demonstrates the ability of Swift/UVOT to investigate the properties of hot luminous stars. We further find that the models reproduce the photometric measures in all 11 passbands to within their systematic uncertainties. Within the limits of our photometry, we find the standard stars to be photometrically stable. This success indicates that the models can be used to calibrate additional filters to our standard system, permitting easier comparison of photometry from heterogeneous sources. The largest source of uncertainty in the model fitting is the uncertainty in the foreground reddening curve, a problem that is especially acute in the UV.

Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.

Directory of Open Access Journals (Sweden)

Michelle Visagie

Full Text Available 2-Methoxyestradiol (2ME2 is a naturally occurring estradiol metabolite which possesses antiproliferative, antiangiogenic and antitumor properties. However, due to its limited biological accessibility, synthetic analogues have been synthesized and tested in attempt to develop drugs with improved oral bioavailability and efficacy. The aim of this study was to evaluate the antiproliferative effects of three novel in silico-designed sulphamoylated 2ME2 analogues on the HeLa cervical adenocarcinoma cell line and estrogen receptor-negative breast adenocarcinoma MDA-MB-231 cells. A dose-dependent study (0.1-25 μM was conducted with an exposure time of 24 hours. Results obtained from crystal violet staining indicated that 0.5 μM of all 3 compounds reduced the number of cells to 50%. Lactate dehydrogenase assay was used to assess cytotoxicity, while the mitotracker mitochondrial assay and caspase-6 and -8 activity assays were used to investigate the possible occurrence of apoptosis. Tubulin polymerization assays were conducted to evaluate the influence of these sulphamoylated 2ME2 analogues on tubulin dynamics. Double immunofluorescence microscopy using labeled antibodies specific to tyrosinate and detyrosinated tubulin was conducted to assess the effect of the 2ME2 analogues on tubulin dynamics. An insignificant increase in the level of lactate dehydrogenase release was observed in the compounds-treated cells. These sulphamoylated compounds caused a reduction in mitochondrial membrane potential, cytochrome c release and caspase 3 activation indicating apoptosis induction by means of the intrinsic pathway in HeLa and MDA-MB-231 cells. Microtubule depolymerization was observed after exposure to these three sulphamoylated analogues.

Difference in brain activations during appreciating paintings and photographic analogues

Directory of Open Access Journals (Sweden)

Yoshinori eMizokami

2014-07-01

Full Text Available Several studies have investigated neural correlates of aesthetic appreciation for paintings but to date the findings have been heterogeneous. This heterogeneity may be attributed to previous studies’ measurement of aesthetic appreciation of not only the beauty of paintings but also the beauty of motifs of the paintings. In order to better elucidate the beauty of paintings, it seems necessary to compare aesthetic appreciation of paintings and photographic analogues which included corresponding real images. We prepared for famous painters’ pictures and their photographic analogues which were set up to resemble each painting in order to investigate the hypothesis that there exist specific neural correlates associated with the aesthetic appreciation for paintings. Forty-four subjects participated in functional magnetic resonance study which required comparisons of aesthetic appreciation of paintings of still life and landscape versus photographic analogues including corresponding real images of still life and landscape. Bilateral cuneus and the left lingual gyrus were activated in the comparison of aesthetic appreciation of paintings versus photographic analogues. In conclusion, the present findings suggest a possibility of the existence of specific neural correlates associated with the aesthetic appreciation for paintings and that bilateral cuneus and the left lingual gyrus may be involved.

Study on interaction of swift cluster ion beam with matter and irradiation effect (Joint research)

International Nuclear Information System (INIS)

Saito, Yuichi; Shibata, Hiromi

2010-07-01

This review covers results of the 'Study of interaction on swift cluster ion beam with matter and irradiation effect' supported by the Interorganization Atomic Energy Research Program from 2006FY to 2008FY. It is composed of a research abstract for each sub-group with viewgraphs which were presented at the group meeting held on March 2009 or 'Meeting of High LET radiation -From fundamental study among physics, chemistry and biology to medical applications-' sponsored by Japan Society of Radiation Chemistry, cosponsored by this research group. (author)

Space Telescope and Optical Reverberation Mapping Project. II. Swift and HST Reverberation Mapping of the Accretion Disk of NGC 5548

NARCIS (Netherlands)

Edelson, R.; Gelbord, J.M.; Horne, K.; McHardy, I.M.; Peterson, B.M.; Arévalo, P.; Breeveld, A.A.; De Rosa, G.; Evans, P.A.; Goad, M.R.; Kriss, G.A.; Brandt, W.N.; Gehrels, N.; Grupe, D.; Kennea, J.A.; Kochanek, C.S.; Nousek, J.A.; Papadakis, I.; Siegel, M.; Starkey, D.; Uttley, P.; Vaughan, S.; Young, S.; Barth, A.J.; Bentz, M.C.; Brewer, B.J.; Crenshaw, D.M.; Dalla Bontà, E.; De Lorenzo-Cáceres, A.; Denney, K.D.; Dietrich, M.; Ely, J.; Fausnaugh, M.M.; Grier, C.J.; Hall, P.B.; Kaastra, J.; Kelly, B.C.; Korista, K.T.; Lira, P.; Mathur, S.; Netzer, H.; Pancoast, A.; Pei, L.; Pogge, R.W.; Schimoia, J.S.; Treu, T.; Vestergaard, M.; Villforth, C.; Yan, H.; Zu, Y.

2015-01-01

Recent intensive Swift monitoring of the Seyfert 1 galaxy NGC 5548 yielded 282 usable epochs over 125 days across six UV/optical bands and the X-rays. This is the densest extended active galactic nucleus (AGN) UV/optical continuum sampling ever obtained, with a mean sampling rate <0.5 day.

Introducing New Antimalarial Analogues of Chloroquine and Amodiaquine: A Narrative Review

Directory of Open Access Journals (Sweden)

Arezoo Rafiee Parhizgar

2017-03-01

Full Text Available Antimalarial drugs with the 4-aminoquinoline scaffold such as the important drugs, chloroquine (CQ and amodiaquine (AQ, have been used to prevent and treat malaria for many years. The importance of these drugs is related to their simple usage, high efficacy, affordability, and cost-effectiveness of their synthesis. In recent years, with the spread of parasite resistance to CQ and cross-resistance to its other analogues have decreased their consumption in many geographical areas. On the other hand, AQ is an effective antimalarial drug which its usage has been restricted due to hepatic and hematological toxicities. The significance of the quinoline ring at quinoline-based antimalarial drugs has prompted research centers and pharmaceutical companies to focus on the design and synthesis of new analogues of these drugs, especially CQ and AQ analogues. Accordingly, various derivatives have been synthesized and evaluated in vitro and in vivo against the resistant strains of the malaria parasite to solve the problem of drug resistance. Also, the pharmacokinetic properties of these compounds have been evaluated to augment their efficacy and diminish their toxicity. Some of these analogues are currently in clinical and preclinical development. Consequently, the recent researches showed yet 4-aminoquinoline scaffold is active moiety in new compounds with antiplasmodial activity. Hence, the aim of this review article is to introduce of the novel synthetic analogues of CQ and AQ, which may constitute the next generation of antimalarial drugs with the 4-aminoquinoline scaffold.

Introducing New Antimalarial Analogues of Chloroquine and Amodiaquine: A Narrative Review.

Science.gov (United States)

Parhizgar, Arezoo Rafiee; Tahghighi, Azar

2017-03-01

Antimalarial drugs with the 4-aminoquinoline scaffold such as the important drugs, chloroquine (CQ) and amodiaquine (AQ), have been used to prevent and treat malaria for many years. The importance of these drugs is related to their simple usage, high efficacy, affordability, and cost-effectiveness of their synthesis. In recent years, with the spread of parasite resistance to CQ and cross-resistance to its other analogues have decreased their consumption in many geographical areas. On the other hand, AQ is an effective antimalarial drug which its usage has been restricted due to hepatic and hematological toxicities. The significance of the quinoline ring at quinoline-based antimalarial drugs has prompted research centers and pharmaceutical companies to focus on the design and synthesis of new analogues of these drugs, especially CQ and AQ analogues. Accordingly, various derivatives have been synthesized and evaluated in vitro and in vivo against the resistant strains of the malaria parasite to solve the problem of drug resistance. Also, the pharmacokinetic properties of these compounds have been evaluated to augment their efficacy and diminish their toxicity. Some of these analogues are currently in clinical and preclinical development. Consequently, the recent researches showed yet 4-aminoquinoline scaffold is active moiety in new compounds with antiplasmodial activity. Hence, the aim of this review article is to introduce of the novel synthetic analogues of CQ and AQ, which may constitute the next generation of antimalarial drugs with the 4-aminoquinoline scaffold.

Synthesis of tritium labelled phosphonate analogues of sphinganine-1-phosphate

International Nuclear Information System (INIS)

Schick, Andreas; Schwarzmann, Guenter; Kolter, Thomas; Sandhoff, Konrad

1997-01-01

Tritiated phosphonate analogues 9 and 10 are prepared as analogues of sphinganine-1-phosphate 4. The key step in this synthesis is the catalytic tritiation of the triple bond in reduction of the protected diethyl-3-(S)-tert.-butoxycarbonylamino -4-hydroxy-5-tridecinyl-1-phosphonate by means of sodium boro[ 3 H]hydride as tritium source. These compounds are synthesized to study their metabolic stability and to evaluate their biological properties. (author)

Energy metabolism and memory processing: role of glucose transport and glycogen in responses to adrenoceptor activation in the chicken.

Science.gov (United States)

Hutchinson, Dana S; Summers, Roger J; Gibbs, Marie E

2008-06-15

From experiments using a discriminated bead task in young chicks, we have defined when and where adrenoceptors (ARs) are involved in memory modulation. All three ARs subtypes (alpha(1)-, alpha(2)- and beta-ARs) are found in the chick brain and in regions associated with memory. Glucose and glycogen are important in the role of memory consolidation in the chick since increasing glucose levels improves memory consolidation while inhibiting glucose transporters (GLUTs) or glycogen breakdown inhibits memory consolidation. The selective beta(3)-AR agonist CL316243 enhances memory consolidation by a glucose-dependent mechanism and the administration of the non-metabolized glucose analogue 2-deoxyglucose reduces the ability of CL316243 to enhance memory. Agents that reduce glucose uptake by GLUTs and its incorporation into the glycolytic pathway also reduce the effectiveness of CL316243, but do not alter the dose-response relationship to the beta(2)-AR agonist zinterol. However, beta(2)-ARs do have a role in memory related to glycogen breakdown and inhibition of glycogenolysis reduces the ability of zinterol to enhance memory. Both beta(2)- and beta(3)-ARs are found on astrocytes from chick forebrain, and the actions of beta(3)-ARs on glucose uptake, and beta(2)-ARs on the breakdown of glycogen is consistent with an effect on astrocytic metabolism at the time of memory consolidation 30 min after training. We have shown that both beta(2)- and beta(3)-ARs can increase glucose uptake in chick astrocytes but do so by different mechanisms. This review will focus on the role of ARs on memory consolidation and specifically the role of energy metabolism on AR modulation of memory.

A silyl andrographolide analogue suppresses Wnt/β-catenin signaling pathway in colon cancer.

Science.gov (United States)

Reabroi, Somrudee; Chairoungdua, Arthit; Saeeng, Rungnapha; Kasemsuk, Teerapich; Saengsawang, Witchuda; Zhu, Weiming; Piyachaturawat, Pawinee

2018-05-01

Hyperactivation of Wnt/β-catenin signaling implicated in oncogenesis of colorectal cancer (CRC) is a potential molecular target for chemotherapy. An andrographolide analogue, 3A.1 (19-tert-butyldiphenylsilyl-8, 17-epoxy andrographolide) has previously been reported to be potently cytotoxic toward cancer cells by unknown molecular mechanisms. The present study explored the anti-cancer activity of analogue 3A.1 on Wnt/β-catenin signaling in colon cancer cells (HT29 cells) which were more sensitive to the others (HCT116 and SW480 cells). Analogue 3A.1 inhibited viability of HT29 cells with IC 50 value of 11.1 ± 1.4 μM at 24 h, which was more potent than that of the parent andrographolide. Analogue 3A.1 also suppressed the proliferation of HT29 cells and induced cell apoptosis in a dose-dependent manner. Its apoptotic activity was accompanied with increased expressions of proteins related to DNA damages; PARP-1 and γ-H2AX. In addition, analogue 3A.1 significantly inhibited T-cell factor and lymphoid enhancer factor (TCF/LEF) promoter activity of Wnt/β-catenin signaling. Accordingly, the expressions of Wnt target genes and β-catenin protein were suppressed. Moreover, analogue 3A.1 increased the activity of GSK-3β kinase, which is a negative regulator responsible for degradation of intracellular β-catenin. This mode of action was further supported by the absence of the effects after treatment with a GSK-3β inhibitor, and over-expression of a mutant β-catenin (S33Y). Our findings reveal, for the first time, an insight into the molecular mechanism of the anti-cancer activity of analogue 3A.1 through the inhibition of Wnt/β-catenin/GSK-3β pathway and provide a therapeutic potential of the andrographolide analogue 3A.1 in CRC treatment. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Synthesis and formulation studies of griseofulvin analogues with improved solubility and metabolic stability

DEFF Research Database (Denmark)

Petersen, Asger Bjørn; Andersen, Nikolaj Sten; Konotop, Gleb

2017-01-01

Griseofulvin (1) is an important antifungal agent that has recently received attention due to its antiproliferative activity in mammalian cancer cells. Comprehensive SAR studies have led to the identification of 2'-benzyloxy griseofulvin 2, a more potent analogue with low micromolar anticancer...... potency in vitro. Analogue 2 was also shown to retard tumor growth through inhibition of centrosomal clustering in murine xenograft models of colon cancer and multiple myeloma. However, similar to griseofulvin, compound 2 exhibited poor metabolic stability and aqueous solubility. In order to improve...... studies. The 2'-benzylamine analogue 10 proved to be the most promising compound with low μM in vitro anticancer potency, a 200-fold increase in PBS solubility over compound 2, and with improved metabolic stability. Furthermore, this analogue proved compatible with formulations suitable for both oral...

STUDYING FAINT ULTRA-HARD X-RAY EMISSION FROM AGN IN GOALS LIRGS WITH SWIFT/BAT

International Nuclear Information System (INIS)

Koss, Michael; Casey, Caitlin M.; Mushotzky, Richard; Veilleux, Sylvain; Baumgartner, Wayne; Tueller, Jack; Markwardt, Craig

2013-01-01

We present the first analysis of the all-sky Swift Burst Alert Telescope (BAT) ultra-hard X-ray (14-195 keV) data for a targeted list of objects. We find that the BAT data can be studied at three-times-fainter limits than in previous blind detection catalogs based on prior knowledge of source positions and using smaller energy ranges for source detection. We determine the active galactic nucleus (AGN) fraction in 134 nearby (z IR /L ☉ > 11.8) detected. The BAT AGN classification shows 97% (37/38) agreement with Chandra and XMM-Newton AGN classification using hardness ratios or detection of an iron Kα line. This confirms our statistical analysis and supports the use of the Swift/BAT all-sky survey to study fainter populations of any category of sources in the ultra-hard X-ray band. BAT AGNs in LIRGs tend to show higher column densities with 40% ± 9% showing 14-195 keV/2-10 keV hardness flux ratios suggestive of high or Compton-thick column densities (log N H > 24 cm –2 ), compared to only 12% ± 5% of non-LIRG BAT AGNs. We also find that using specific energy ranges of the BAT detector can yield additional sources over total band detections with 24% (5/21) of detections in LIRGs at 24-35 keV not detected at 14-195 keV.

Natural analogue synthesis report, TDR-NBS-GS-000027 REV00 ICN02

International Nuclear Information System (INIS)

Simmons, A.; Nieder-Westermann, G.; Stuckless, J.; Dobson, P.; Unger, A.J.A.; Kwicklis, E.; Lichtner, P.; Carey, B.; Wolde, G.; Murrel, M.; Kneafsey, T.J.; Meijer, A.; Faybishenko, B.

2002-01-01

The purpose of this report is to present analogue studies and literature reviews designed to provide qualitative and quantitative information to test and provide added confidence in process models abstracted for performance assessment (PA) and model predictions pertinent to PA. This report provides updates to studies presented in the Yucca Mountain Site Description (CRWMS M and O 2000 [151945], Section 13) and new examples gleaned from the literature, along with results of quantitative studies conducted specifically for the Yucca Mountain Site Characterization Project (YMP). The intent of the natural analogue studies was to collect corroborative evidence from analogues to demonstrate additional understanding of processes expected to occur during postclosure at a potential Yucca Mountain repository. The report focuses on key processes by providing observations and analyses of natural and anthropogenic (human-induced) systems to improve understanding and confidence in the operation of these processes under conditions similar to those that could occur in a nuclear waste repository. The process models include those that represent both engineered and natural barrier processes. A second purpose of this report is to document the various applications of natural analogues to geologic repository programs, focusing primarily on the way analogues have been used by the YMP. This report is limited to providing support for PA in a confirmatory manner and to providing corroborative inputs for process modeling activities. Section 1.7 discusses additional limitations of this report. Key topics for this report are analogues to emplacement drift degradation, waste form degradation, waste package degradation, degradation of other materials proposed for the engineered barrier, seepage into drifts, radionuclide flow and transport in the unsaturated zone (UZ), analogues to coupled thermal-hydrologic-mechanical-chemical processes, saturated zone (SZ) transport, impact of radionuclide

Natural analogue synthesis report, TDR-NBS-GS-000027 rev00 icn02

Energy Technology Data Exchange (ETDEWEB)

Simmons, A.; Nieder-Westermann, G.; Stuckless, J.; Dobson, P.; Unger, A.J.A.; Kwicklis, E.; Lichtner, P.; Carey, B.; Wolde, G.; Murrel,M.; Kneafsey, T.J.; Meijer, A.; Faybishenko, B.

2002-04-01

The purpose of this report is to present analogue studies and literature reviews designed to provide qualitative and quantitative information to test and provide added confidence in process models abstracted for performance assessment (PA) and model predictions pertinent to PA. This report provides updates to studies presented in the Yucca Mountain Site Description (CRWMS M&O 2000 [151945], Section 13) and new examples gleaned from the literature, along with results of quantitative studies conducted specifically for the Yucca Mountain Site Characterization Project (YMP). The intent of the natural analogue studies was to collect corroborative evidence from analogues to demonstrate additional understanding of processes expected to occur during postclosure at a potential Yucca Mountain repository. The report focuses on key processes by providing observations and analyses of natural and anthropogenic (human-induced) systems to improve understanding and confidence in the operation of these processes under conditions similar to those that could occur in a nuclear waste repository. The process models include those that represent both engineered and natural barrier processes. A second purpose of this report is to document the various applications of natural analogues to geologic repository programs, focusing primarily on the way analogues have been used by the YMP. This report is limited to providing support for PA in a confirmatory manner and to providing corroborative inputs for process modeling activities. Section 1.7 discusses additional limitations of this report. Key topics for this report are analogues to emplacement drift degradation, waste form degradation, waste package degradation, degradation of other materials proposed for the engineered barrier, seepage into drifts, radionuclide flow and transport in the unsaturated zone (UZ), analogues to coupled thermal-hydrologic-mechanical-chemical processes, saturated zone (SZ) transport, impact of radionuclide release

The importance of analogue zeitgebers to reduce digital addictive tendencies in the 21st century

Directory of Open Access Journals (Sweden)

Christian Montag

2015-12-01

Full Text Available Analogue zeitgebers such as wristwatches and alarm clocks are essential for structuring everyday life. Since the dawn of the digital revolution – particularly since the advent of the smartphone – mobile phones have increasingly replaced analogue zeitgebers as a means of telling time. This functionality may prove problematic, in that it may contribute to the overuse of digital media (e.g. when checking the time turns into extended use of other smartphone utilities, including Internet-based applications. Of N = 3084 participants, 45% reported wearing a wristwatch and 67% used an analogue alarm clock. We observed that participants who reported using analogue zeitgebers used their mobile-/smartphone significantly less. Use of analogue zeitgebers may prove a practical tool for therapeutic and preventative interventions for problematic Internet use in an increasingly digital age.

PENGEMBANGAN BERAS ANALOG DENGAN MEMANFAATKAN JAGUNG PUTIH [Development of White Corn-Based Rice Analogues

Directory of Open Access Journals (Sweden)

Santi Noviasari*

2013-12-01

Full Text Available White corn can be utilized as a source of non-rice carbohydrate in the manufacture of rice analogues. The rice analogues with rice-like characteristics were produced by an extrusion technique. The aim of this research was to develop rice analogues from white corn and to evaluate their physicochemical and sensory properties. The study was conducted in several stages, i.e. preparation, formulation, and physicochemical and sensory properties evaluation. The physicochemical properties of rice analogues evaluated included proximate nutritional composition, dietary fiber concentration, cooking time, water loss rate, color, and whiteness percentage, while their sensory preferences were evaluated using hedonic scale test. The rice analogues made of Pulut Harapan and Lokal Purbalingga corns (4.34:65.66% added with 30% sago starch, was found to be the most preferred. The moisture, ash, protein, fat, carbohydrate, and dietary fiber composition of this rice analog was 9.32, 0.38, 6.86, 1.22, 91.54, and 5.35%, respectively.

Synthesis and preliminary pharmacological evaluation of asymmetric chloroquine analogues.

Science.gov (United States)

Witiak, D T; Grattan, D A; Heaslip, R J; Rahwan, R G

1981-06-01

Asymmetric chloroquine analogues (1-4) were prepared of known absolute configuration in order to assess stereochemical influences on selected biological activities. Since chloroquine has been shown to possess spasmolytic properties, analogues 1-4 were tested for similar pharmacological effects on smooth-muscle contraction. The (S)- and (R)-chlorochloroquine enantiomers (1 and 2, respectively) were more potent antispasmodics than the less lipophilic (S)- and (R)-hydroxychloroquines (3 and 4, respectively) when tested against KCl- or acetylcholine-induced contractions of the isolated mouse ileum. A membrane stabilizing mechanism of action for the chloroquine analogues is proposed since neither cellular toxicity nor calcium antagonism plays a role in the spasmolytic action of these compounds. Although compounds 1-4 also inhibited PGF2 alpha-induced contractions of the ileum, 1 was significantly more potent than 2; the latter in turn was equipotent to 3 and 4. It is tentatively proposed that 1 may possess stereoselective affinity for the PGF2 alpha receptor in the ileum. This observation may be further exploited to obtain more selective profiles of biological activity through molecular manipulation.

Do film soundtracks contain nonlinear analogues to influence emotion?

Science.gov (United States)

Blumstein, Daniel T; Davitian, Richard; Kaye, Peter D

2010-12-23

A variety of vertebrates produce nonlinear vocalizations when they are under duress. By their very nature, vocalizations containing nonlinearities may sound harsh and are somewhat unpredictable; observations that are consistent with them being particularly evocative to those hearing them. We tested the hypothesis that humans capitalize on this seemingly widespread vertebrate response by creating nonlinear analogues in film soundtracks to evoke particular emotions. We used lists of highly regarded films to generate a set of highly ranked action/adventure, dramatic, horror and war films. We then scored the presence of a variety of nonlinear analogues in these film soundtracks. Dramatic films suppressed noise of all types, contained more abrupt frequency transitions and musical sidebands, and fewer noisy screams than expected. Horror films suppressed abrupt frequency transitions and musical sidebands, but had more non-musical sidebands, and noisy screams than expected. Adventure films had more male screams than expected. Together, our results suggest that film-makers manipulate sounds to create nonlinear analogues in order to manipulate our emotional responses.

Do GnRH analogues directly affect human endometrial epithelial cell gene expression?

KAUST Repository

Zhang, Xiaomei; Bocca, Silvina Maria; Franchi, Anahí ; Anderson, Sandra; Kaur, Mandeep; Bajic, Vladimir B.; Oehninger, Sergio Carlos

2010-01-01

were: (i) to study the modulatory effect of GnRH analogues by RT-PCR [in the absence and presence of E2 and P4, and cyclic adenosine monophos-phate (cAMP)] on mRNA expression of genes modulated during the window of implantation in GnRH analogues

A Potential Tool for Swift Fox (Vulpes velox) Conservation: Individuality of Long-Range Barking Sequences

DEFF Research Database (Denmark)

Darden, Safi-Kirstine Klem; Dabelsteen, Torben; Pedersen, Simon Boel

2003-01-01

Vocal individuality has been found in a number canid species. This natural variation can have applications in several aspects of species conservation, from behavioral studies to estimating population density or abundance. The swift fox (Vulpes velox) is a North American canid listed as endangered...... in Canada and extirpated, endangered, or threatened in parts of the United States. The barking sequence is a long-range vocalization in the species' vocal repertoire. It consists of a series of barks and is most common during the mating season. We analyzed barking sequences recorded in a standardized...

Distortions in recall from visual memory: two classes of attractors at work.

Science.gov (United States)

Huang, Jie; Sekuler, Robert

2010-02-24

In a trio of experiments, a matching procedure generated direct, analogue measures of short-term memory for the spatial frequency of Gabor stimuli. Experiment 1 showed that when just a single Gabor was presented for study, a retention interval of just a few seconds was enough to increase the variability of matches, suggesting that noise in memory substantially exceeds that in vision. Experiment 2 revealed that when a pair of Gabors was presented on each trial, the remembered appearance of one of the Gabors was influenced by: (1) the relationship between its spatial frequency and the spatial frequency of the accompanying, task-irrelevant non-target stimulus; and (2) the average spatial frequency of Gabors seen on previous trials. These two influences, which work on very different time scales, were approximately additive in their effects, each operating as an attractor for remembered appearance. Experiment 3 showed that a timely pre-stimulus cue allowed selective attention to curtail the influence of a task-irrelevant non-target, without diminishing the impact of the stimuli seen on previous trials. It appears that these two separable attractors influence distinct processes, with perception being influenced by the non-target stimulus and memory being influenced by stimuli seen on previous trials.

Swift heavy ion irradiation effects on carbonyl and trans-vinylene groups in high and low density polyethylene

International Nuclear Information System (INIS)

Grosso, M.F. del; Chappa, V.C.; Arbeitman, C.R.; Garcia Bermudez, G.; Behar, M.

2009-01-01

In this work, we have studied the effects of swift heavy ion irradiation on the creation of new functional groups in high and low density polyethylene (HDPE and LDPE). Polymers were irradiated with different ions (6.77 MeV He and 47 MeV Li) and fluences. The induced changes were analyzed by Fourier transform infrared (FTIR) spectroscopy. Creation and damage cross sections for some groups were compared for two different types of PE.

A Theoretical Analysis of the Perceptual Span based on SWIFT Simulations of the n + 2 Boundary Paradigm

OpenAIRE

Risse, Sarah; Hohenstein, Sven; Kliegl, Reinhold; Engbert, Ralf

2014-01-01

Eye-movement experiments suggest that the perceptual span during reading is larger than the fixated word, asymmetric around the fixation position, and shrinks in size contingent on the foveal processing load. We used the SWIFT model of eye-movement control during reading to test these hypotheses and their implications under the assumption of graded parallel processing of all words inside the perceptual span. Specifically, we simulated reading in the boundary paradigm and analysed the effects ...

Swift heavy ion irradiation effects on carbonyl and trans-vinylene groups in high and low density polyethylene

Energy Technology Data Exchange (ETDEWEB)

Grosso, M.F. del, E-mail: delgrosso@tandar.cnea.gov.a [Gerencia de Investigacion y Aplicaciones, TANDAR-CNEA (Argentina); Chappa, V.C. [Gerencia de Investigacion y Aplicaciones, TANDAR-CNEA (Argentina); CONICET (Argentina); Arbeitman, C.R. [Gerencia de Investigacion y Aplicaciones, TANDAR-CNEA (Argentina); Garcia Bermudez, G. [Gerencia de Investigacion y Aplicaciones, TANDAR-CNEA (Argentina); CONICET (Argentina); Escuela de Ciencia y Tecnologia, UNSAM (Argentina); Behar, M. [Instituto de Fisica, UFRGS, Porto Alegre (Brazil)

2009-10-01

In this work, we have studied the effects of swift heavy ion irradiation on the creation of new functional groups in high and low density polyethylene (HDPE and LDPE). Polymers were irradiated with different ions (6.77 MeV He and 47 MeV Li) and fluences. The induced changes were analyzed by Fourier transform infrared (FTIR) spectroscopy. Creation and damage cross sections for some groups were compared for two different types of PE.

q-bosons and the q-analogue quantized field

International Nuclear Information System (INIS)

Nelson, C.A.

1994-01-01

The q-analogue coherent states |z > q are used to identify physical signatures for the presence of a q-analogue quantized radiation field in the | > q classical limit where |z| is large. In this quantum-optics-like limit, the fractional uncertainties of most physical quantities (momentum, position, amplitude, phase) which characterize the quantum field are O(1). They only vanish as O(1/|z|) when q = 1. However, for the number operator, N, and the N-Hamiltonian for a free q-boson gas, H N = ℎω(N + 1/2), the fractional uncertainties do still approach zero. A signature for q-boson counting statistics is that (ΔN) 2 / → 0 as |z| → ∞. Except for its O(1) fractional uncertainty, the q-generalization of the Hermitian phase operator of Pegg and Barnett, φ q , still exhibits normal classical behavior. The standard number-phase uncertainty-relation, ΔN Δφ q = 1/2, and the approximate commutation relation, [N,φ q ] = i, still hold for the single-mode q-analogue quantized field. So, N and φ q are almost canonically conjugate operators in the |z > q classical limit. The |z > q CS's minimize this uncertainty relation for moderate |z| 2

Damage induced in semiconductors by swift heavy ion irradiation

International Nuclear Information System (INIS)

Levalois, M.; Marie, P.

1999-01-01

The behaviour of semiconductors under swift heavy ion irradiation is different from that of metals or insulators: no spectacular effect induced by the inelastic energy loss has been reported in these materials. We present here a review of irradiation effects in the usual semiconductors (silicon, germanium and gallium arsenide). The damage is investigated by means of electrical measurements. The usual mechanisms of point defect creation can account for the experimental results. Besides, some results obtained on the wide gap semiconductor silicon carbide are reported. Concerning the irradiation effects induced by heavy ions in particle detectors, based on silicon substrate, we show that the deterioration of the detector performances can be explained from the knowledge of the substrate properties which are strongly perturbed after high doses of irradiation. Finally, some future ways of investigation are proposed. The silicon substrate is a good example to compare the irradiation effects with different particles such as electrons, neutrons and heavy ions. It is then necessary to use parameters which account for the local energy deposition, in order to describe the damage in the material

Higher-dimensional analogues of Donaldson-Witten theory

International Nuclear Information System (INIS)

Acharya, B.S.; Spence, B.

1997-01-01

We present a Donaldson-Witten-type field theory in eight dimensions on manifolds with Spin(7) holonomy. We prove that the stress tensor is BRST exact for metric variations preserving the holonomy and we give the invariants for this class of variations. In six and seven dimensions we propose similar theories on Calabi-Yau threefolds and manifolds of G 2 holonomy, respectively. We point out that these theories arise by considering supersymmetric Yang-Mills theory defined on such manifolds. The theories are invariant under metric variations preserving the holonomy structure without the need for twisting. This statement is a higher-dimensional analogue of the fact that Donaldson-Witten field theory on hyper-Kaehler 4-manifolds is topological without twisting. Higher-dimensional analogues of Floer cohomology are briefly outlined. All of these theories arise naturally within the context of string theory. (orig.)

Making Connections in Math: Activating a Prior Knowledge Analogue Matters for Learning

Science.gov (United States)

Sidney, Pooja G.; Alibali, Martha W.

2015-01-01

This study investigated analogical transfer of conceptual structure from a prior-knowledge domain to support learning in a new domain of mathematics: division by fractions. Before a procedural lesson on division by fractions, fifth and sixth graders practiced with a surface analogue (other operations on fractions) or a structural analogue (whole…

The anti-inflammatory activity of dillapiole and some semisynthetic analogues.

Science.gov (United States)

Parise-Filho, Roberto; Pastrello, Michelli; Pereira Camerlingo, Carla Emygdio; Silva, Gisele Juni; Agostinho, Leonardo Aguiar; de Souza, Thaís; Motter Magri, Fátima Maria; Ribeiro, Roberto Rodrigues; Brandt, Carlos Alberto; Polli, Michelle Carneiro

2011-11-01

Piper aduncum L. (Piperaceae) produces an essential oil (dillapiole) with great exploitative potential and it has proven effects against traditional cultures of phytopathogens, such as fungi, bacteria and mollusks, as well as analgesic action with low levels of toxicity. This study investigated the in vivo anti-inflammatory activity of dillapiole. Furthermore, in order to elucidate its structure-anti-inflammatory activity relationship (SAR), semisynthetic analogues were proposed by using the molecular simplification strategy. Dillapiole and safrole were isolated and purified using column chromatography. The semisynthetic analogues were obtained by using simple organic reactions, such as catalytic reduction and isomerization. All the analogues were purified by column chromatography and characterized by (1)H and (13)C NMR. The anti-inflammatory activities of dillapiole and its analogues were studied in carrageenan-induced rat paw edema model. Dillapiole and di-hydrodillapiole significantly (p<0.05) inhibited rat paw edema. All the other substances tested, including safrole, were less powerful inhibitors with activities inferior to that of indomethacin. These findings showed that dillapiole and di-hydrodillapiole have moderate anti-phlogistic properties, indicating that they can be used as prototypes for newer anti-inflammatory compounds. Structure-activity relationship studies revealed that the benzodioxole ring is important for biological activity as well as the alkyl groups in the side chain and the methoxy groups in the aromatic ring.