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Sample records for swedish mutant app

  1. The Swedish mutant barley collection

    International Nuclear Information System (INIS)

    1989-01-01

    Full text: The Swedish mutation research programme in barley began about 50 years ago and has mainly been carried out at Svaloev in co-operation with the institute of Genetics at the University of Lund. The collection has been produced from different Swedish high-yielding spring barley varieties, using the following mutagens: X-rays, neutrons, several organic chemical compounds such as ethyleneimine, several sulfonate derivatives and the inorganic chemical mutagen sodium azide. Nearly 10,000 barley mutants are stored in the Nordic Gene Bank and documented in databases developed by Udda Lundquist, Svaloev AB. The collection consists of the following nine categories with 94 different types of mutants: 1. Mutants with changes in the spike and spikelets; 2. Changes in culm length and culm composition; 3. Changes in growth types; 4. Physiological mutants; 5. Changes in awns; 6. Changes in seed size and shape; 7. Changes in leaf blades; 8. Changes in anthocyanin and colour; 9. Resistance to barley powdery mildew. Barley is one of the most thoroughly investigated crops in terms of induction of mutations and mutation genetics. So far, about half of the mutants stored at the Nordic Gene Bank, have been analysed genetically; They constitute, however, only a minority of the 94 different mutant types. The genetic analyses have given valuable insights into the mutation process but also into the genetic architecture of various characters. A number of mutants of two-row barley have been registered and commercially released. One of the earliest released, Mari, an early maturing, daylength neutral, straw stiff mutant, is still grown in Iceland. The Swedish mutation material has been used in Sweden, but also in other countries, such as Denmark, Germany, and USA, for various studies providing a better understanding of the barley genome. The collection will be immensely valuable for future molecular genetical analyses of clone mutant genes. (author)

  2. A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation

    DEFF Research Database (Denmark)

    Folkesson, Ronnie; Malkiewicz, Katarzyna; Kloskowska, Ewa

    2007-01-01

    protein (APP) containing the Swedish AD mutation. The highest level of expression in the brain is found in the cortex, hippocampus, and cerebellum. Starting after the age of 15 months, the rats show increased tau phosphorylation and extracellular Abeta staining. The Abeta is found predominantly...

  3. Low-Density Lipoprotein Receptor-Related Protein-1 (LRP1) C4408R Mutant Promotes Amyloid Precursor Protein (APP) α-Cleavage in Vitro.

    Science.gov (United States)

    Hou, Huayan; Habib, Ahsan; Zi, Dan; Tian, Kathy; Tian, Jun; Giunta, Brian; Sawmiller, Darrell; Tan, Jun

    2017-09-01

    Previous studies have demonstrated that the low-density lipoprotein receptor-related protein-1 (LRP1) plays conflicting roles in Alzheimer's disease (AD) pathogenesis, clearing β-amyloid (Aβ) from the brain while also enhancing APP endocytosis and resultant amyloidogenic processing. We have recently discovered that co-expression of mutant LRP1 C-terminal domain (LRP1-CT C4408R) with Swedish mutant amyloid precursor protein (APPswe) in Chinese hamster ovary (CHO) cells decreases Aβ production, while also increasing sAPPα and APP α-C-terminal fragment (α-CTF), compared with CHO cells expressing APPswe alone. Surprisingly, the location of this mutation on LRP1 corresponded with the α-secretase cleavage site of APP. Further experimentation confirmed that in CHO cells expressing APPswe or wild-type APP (APPwt), co-expression of LRP1-CT C4408R decreases Aβ and increases sAPPα and α-CTF compared with co-expression of wild-type LRP1-CT. In addition, LRP1-CT C4408R enhanced the unglycosylated form of LRP1-CT and reduced APP endocytosis as determined by flow cytometry. This finding identifies a point mutation in LRP1 which slows LRP1-CT-mediated APP endocytosis and amyloidogenic processing, while enhancing APP α-secretase cleavage, thus demonstrating a potential novel target for slowing AD pathogenesis.

  4. Evaluation of the Expression of Amyloid Precursor Protein and the Ratio of Secreted Amyloid Beta 42 to Amyloid Beta 40 in SH-SY5Y Cells Stably Transfected with Wild-Type, Single-Mutant and Double-Mutant Forms of the APP Gene for the Study of Alzheimer's Disease Pathology.

    Science.gov (United States)

    Pahrudin Arrozi, Aslina; Shukri, Siti Nur Syazwani; Wan Ngah, Wan Zurinah; Mohd Yusof, Yasmin Anum; Ahmad Damanhuri, Mohd Hanafi; Makpol, Suzana

    2017-11-01

    Neuroblastoma cell lines such as SH-SY5Y are the most frequently utilized models in neurodegenerative research, and their use has advanced the understanding of the pathology of neurodegeneration over the past few decades. In Alzheimer's disease (AD), several pathogenic mutations have been described, all of which cause elevated levels of pathological hallmarks such as amyloid-beta (Aβ). Although the genetics of Alzheimer's disease is well known, familial AD only accounts for a small number of cases in the population, with the rest being sporadic AD, which contains no known mutations. Currently, most of the in vitro models used to study AD pathogenesis only examine the level of Aβ42 as a confirmation of successful model generation and only perform comparisons between wild-type APP and single mutants of the APP gene. Recent findings have shown that the Aβ42/40 ratio in cerebrospinal fluid (CSF) is a better diagnostic indicator for AD patients than is Aβ42 alone and that more extensive Aβ formation, such as accumulation of intraneuronal Aβ, Aβ plaques, soluble oligomeric Aβ (oAβ), and insoluble fibrillar Aβ (fAβ) occurs in TgCRND8 mice expressing a double-mutant form (Swedish and Indiana) of APP, later leading to greater progressive impairment of the brain. In this study, we generated SH-SY5Y cells stably transfected separately with wild-type APP, the Swedish mutation of APP, and the Swedish and Indiana mutations of APP and evaluated the APP expression as well as the Aβ42/40 ratio in those cells. The double-mutant form of APP (Swedish/Indiana) expressed markedly high levels of APP protein and showed a high Aβ2/40 ratio compared to wild-type and single-mutant cells.

  5. Hippocampal Mutant APP and Amyloid Beta Induced Cognitive Decline, Dendritic Spine Loss, Defective Autophagy, Mitophagy and Mitochondrial Abnormalities in a Mouse Model of Alzheimer's Disease.

    Science.gov (United States)

    Manczak, Maria; Kandimalla, Ramesh; Yin, Xiangling; Reddy, P Hemachandra

    2018-02-01

    The purpose of our study was to determine the toxic effects of hippocampal mutant APP and amyloid beta (Aβ) in 12-month-old APP transgenic mice. Using rotarod and Morris Water Maze tests, immunoblotting & immunofluorescence, Golgi-cox staining and transmission electron microscopy, we assessed cognitive behavior, protein levels of synaptic, autophagy, mitophagy, mitochondrial dynamics, biogenesis, dendritic protein MAP2, and quantified dendritic spines and mitochondrial number and length in 12-month-old APP mice that express swedish mutation. Mitochondrial function was assessed by measuring the levels of hydrogen peroxide, lipid peroxidation, cytochrome c oxidase activity and mitochondrial ATP. Morris Water Maze and rotarod tests revealed that hippocampal learning and memory and motor learning & coordination were impaired in APP mice relative to wild-type (WT) mice. Increased levels of mitochondrial fission proteins, Drp1 and Fis1 and decreased levels fusion (Mfn1, Mfn2 and Opa1) biogenesis (PGC1α, NRF1, NRF2 & TFAM), autophagy (ATG5 & LC3BI, LC3BII), Mitophagy (PINK1 & TERT), synaptic (synaptophysin & PSD95) and dendritic (MAP2) proteins were found in 12-month-old APP mice relative to age-matched non-transgenic WT mice. Golgi-cox staining analysis revealed that dendritic spines are significantly reduced. Transmission electron microscopy revealed significantly increased mitochondrial numbers and reduced mitochondrial length in APP mice. These findings suggest that hippocampal accumulation of mutant APP and Aβ is responsible for abnormal mitochondrial dynamics and defective biogenesis, reduced MAP2, autophagy, mitophagy and synaptic proteins & reduced dendritic spines and hippocampal based learning and memory impairments, and mitochondrial structural and functional changes in 12-month-old APP mice. © The Author 2018. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  6. Endosomal-lysosomal Cholesterol Sequestration by U18666A Differentially Regulates APP Metabolism in Normal and APP Overexpressing Cells.

    Science.gov (United States)

    Chung, J; Phukan, G; Vergote, D; Mohamed, A; Maulik, M; Stahn, M; Andrew, R J; Thinakaran, G; Posse de Chaves, E; Kar, S

    2018-03-12

    Amyloid β (Aβ) peptide derived from amyloid precursor protein (APP) plays a critical role in the development of Alzheimer's disease. Current evidence indicates that altered levels/subcellular distribution of cholesterol can regulate Aβ production/clearance, but it remains unclear how cholesterol sequestration within the endosomal-lysosomal (EL) system can influence APP metabolism. Thus, we evaluated the effects of U18666A, which triggers cholesterol redistribution within EL system, on mouse N2a cells expressing different levels of APP in the presence or absence of extracellular cholesterol/lipids provided by fetal bovine serum (FBS). Our results reveal that U18666A and FBS differentially increase the levels of APP and its cleaved products α/β/η-C-terminal fragments in N2a cells expressing normal levels of mouse APP (N2awt) or higher levels of human wild-type APP (APPwt) or "Swedish" mutant APP (APPsw). The cellular levels of Aβ 1-40 /Aβ 1-42 were markedly increased in U18666A-treated APPwt and APPsw cells. Our studies further demonstrate that APP and its cleaved products are partly accumulated in the lysosomes possibly due to decreased clearance. Finally, we show that autophagy inhibition plays a role in mediating U18666A effects. Collectively, these results suggest that altered levels/distribution of cholesterol/lipids can differentially regulate APP metabolism depending on the nature of APP expression. Copyright © 2018 American Society for Microbiology.

  7. Evaluation of the Swedish Web-Version of Quality of Recovery (SwQoR): Secondary Step in the Development of a Mobile Phone App to Measure Postoperative Recovery.

    Science.gov (United States)

    Dahlberg, Karuna; Jaensson, Maria; Eriksson, Mats; Nilsson, Ulrica

    2016-09-28

    The majority of all surgeries are performed on an outpatient basis (day surgery). The Recovery Assessment by Phone Points (RAPP) app is an app for the Swedish Web-version of Quality of Recovery (SwQoR), developed to assess and follow-up on postoperative recovery after day surgery. The objectives of this study are (1) to estimate the extent to which the paper and app versions of the SwQoR provide equivalent values; (2) to contribute evidence as to the feasibility and acceptability of a mobile phone Web-based app for measuring postoperative recovery after day surgery and enabling contact with a nurse; and (3) to contribute evidence as to the content validity of the SwQoR. Equivalence between the paper and app versions of the SwQoR was measured using a randomized crossover design, in which participants used both the paper and app version. Feasibility and acceptability was evaluated by a questionnaire containing 16 questions regarding the value of the app for follow-up care after day surgery. Content validity evaluation was based on responses by day surgery patients and the staff of the day surgery department. A total of 69 participants completed the evaluation of equivalence between the paper and app versions of the SwQoR. The intraclass correlation coefficient (ICC) for the SwQoR was .89 (95% CI 0.83-0.93) and .13 to .90 for the items. Of the participants, 63 continued testing the app after discharge and completed the follow-up questionnaire. The median score was 69 (inter-quartile range, IQR 66-73), indicating a positive attitude toward using an app for follow-up after day surgery. A total of 18 patients and 12 staff members participated in the content validity evaluation. The item-level content validity index (I-CVI) for the staff group was in the 0.64 to 1.0 range, with a scale-level content validity index (S-CVI) of 0.88. For the patient group, I-CVI was in the range 0.30 to 0.92 and S-CVI was 0.67. The content validity evaluation of the SwQoR, together with

  8. The Effects of Extracellular Serum Concentration on APP Processing in Npc1-Deficient APP-Overexpressing N2a Cells.

    Science.gov (United States)

    Maulik, M; Vergote, D; Phukan, G; Chung, J; Thinakaran, G; Kar, S

    2017-10-19

    Amyloid precursor protein (APP) is cleaved by a set of proteases including α-/β-/γ- and recently identified η-secretases, generating C-terminal fragments (CTFs) of varying lengths and amyloid β (Aβ) peptides, which are considered to play a pivotal role in Alzheimer's disease (AD) pathogenesis. Cellular cholesterol content/distribution can regulate the production/clearance of APP metabolites and hence modify AD pathology. To determine the functional relation between endosomal-lysosomal (EL) cholesterol sequestration and APP metabolism, we used our recently developed mouse N2a-ANPC cells that overexpress Swedish mutant human APP in the absence of cholesterol-trafficking Niemann-Pick type C1 (Npc1) protein. Here, we report that neither increased levels nor EL cholesterol sequestration altered APP holoprotein levels but caused the intracellular accumulation of APP α-/β-/η-CTFs and Aβ 1-40/42 peptides. The levels of APP-cleaved products increased as a function of extracellular serum concentration in N2a-ANPC cells, which are more vulnerable to death than the control cells. Additionally, we show that pH of the lysosomal vesicles in N2a-ANPC cells shifted to a less acidic range with increasing serum concentrations, thus making them less efficient functionally. Interestingly, the addition of cholesterol to the culture media not only increased the levels of cellular cholesterol and APP-cleaved products but also rendered the cells more vulnerable to toxicity. Collectively, our results suggest that extracellular cholesterol concentration in serum under conditions of Npc1 deficiency can influence intracellular cholesterol content/distribution and lysosomal efficacy, triggering the accumulation of toxic APP-cleaved products, eventually leading to cell death.

  9. Swedish Projects

    National Research Council Canada - National Science Library

    Borgvall, Jonathan; Lif, Patrik

    2005-01-01

    .... The military research work presented here includes the three military administrations, FOI -- Swedish Defence Research Agency, FMV -- Swedish Defence Materiel Administration, and SNDC -- Swedish...

  10. Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice.

    Science.gov (United States)

    Rijal Upadhaya, Ajeet; Capetillo-Zarate, Estibaliz; Kosterin, Irina; Abramowski, Dorothee; Kumar, Sathish; Yamaguchi, Haruyasu; Walter, Jochen; Fändrich, Marcus; Staufenbiel, Matthias; Thal, Dietmar Rudolf

    2012-11-01

    Soluble amyloid β-protein (Aβ) aggregates have been identified in the Alzheimer's disease (AD) brain. Dispersed Aβ aggregates in the brain parenchyma are different from soluble, membrane-associated and plaque-associated solid aggregates. They are in mixture with the extra- or intracellular fluid but can be separated from soluble proteins by ultracentrifugation. To clarify the role of dispersible Aβ aggregates for neurodegeneration we analyzed 2 different amyloid precursor protein (APP)-transgenic mouse models. APP23 mice overexpress human mutant APP with the Swedish mutation. APP51/16 mice express high levels of human wild type APP. Both mice develop Aβ-plaques. Dendritic degeneration, neuron loss, and loss of asymmetric synapses were seen in APP23 but not in APP51/16 mice. The soluble and dispersible fractions not separated from one another were received as supernatant after centrifugation of native forebrain homogenates at 14,000 × g. Subsequent ultracentrifugation separated the soluble, i.e., the supernatant, from the dispersible fraction, i.e., the resuspended pellet. The major biochemical difference between APP23 and APP51/16 mice was that APP23 mice exhibited higher levels of dispersible Aβ oligomers, protofibrils and fibrils precipitated with oligomer (A11) and protofibril/fibril (B10AP) specific antibodies than APP51/16 mice. These differences, rather than soluble Aβ and Aβ plaque pathology were associated with dendritic degeneration, neuron, and synapse loss in APP23 mice in comparison with APP51/16 mice. Immunoprecipitation of dispersible Aβ oligomers, protofibrils, and fibrils revealed that they were associated with APP C-terminal fragments (APP-CTFs). These results indicate that dispersible Aβ oligomers, protofibrils, and fibrils represent an important pool of Aβ aggregates in the brain that critically interact with membrane-associated APP C-terminal fragments. The concentration of dispersible Aβ aggregates, thereby, presumably determines

  11. App Inventor

    CERN Document Server

    Wolber, David; Spertus, Ellen; Looney, Liz

    2011-01-01

    Yes, you can create your own apps for Android phones-and it's easy to do. This extraordinary book introduces App Inventor for Android, a powerful visual tool that lets anyone build apps for Android-based devices. Learn the basics of App Inventor with step-by-step instructions for more than a dozen fun projects, such as creating location-aware apps, data storage, and apps that include decision-making logic. The second half of the book features an Inventor's manual to help you understand the fundamentals of app building and computer science. App Inventor makes an excellent textbook for beginne

  12. Loss of GABAergic inputs in APP/PS1 mouse model of Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Tutu Oyelami

    2014-04-01

    Full Text Available Alzheimer's disease (AD is characterized by symptoms which include seizures, sleep disruption, loss of memory as well as anxiety in patients. Of particular importance is the possibility of preventing the progressive loss of neuronal projections in the disease. Transgenic mice overexpressing EOFAD mutant PS1 (L166P and mutant APP (APP KM670/671NL Swedish (APP/PS1 develop a very early and robust Amyloid pathology and display synaptic plasticity impairments and cognitive dysfunction. Here we investigated GABAergic neurotransmission, using multi-electrode array (MEA technology and pharmacological manipulation to quantify the effect of GABA Blockers on field excitatory postsynaptic potentials (fEPSP, and immunostaining of GABAergic neurons. Using MEA technology we confirm impaired LTP induction by high frequency stimulation in APPPS1 hippocampal CA1 region that was associated with reduced alteration of the pair pulse ratio after LTP induction. Synaptic dysfunction was also observed under manipulation of external Calcium concentration and input-output curve. Electrophysiological recordings from brain slice of CA1 hippocampus area, in the presence of GABAergic receptors blockers cocktails further demonstrated significant reduction in the GABAergic inputs in APP/PS1 mice. Moreover, immunostaining of GAD65 a specific marker for GABAergic neurons revealed reduction of the GABAergic inputs in CA1 area of the hippocampus. These results might be linked to increased seizure sensitivity, premature death and cognitive dysfunction in this animal model of AD. Further in depth analysis of GABAergic dysfunction in APP/PS1 mice is required and may open new perspectives for AD therapy by restoring GABAergic function.

  13. Photo Apps -

    Data.gov (United States)

    Department of Transportation — Images of various facilities used as a tool to eliminate travel time and for immediate access to concerned areas. App thumbnails images 4 per row and allows the user...

  14. Largo App

    OpenAIRE

    Recasens, Marc

    2017-01-01

    This document evaluates the feasibility of LarGo app business proposal. LarGo is a mobile app focused on improving mobile payments at table-service restaurants. Largo’s goal is to improve the dinning experience for both diners and restaurant operators providing a much faster and easy payment solution. The business intent to make profit from the restaurant industry, which sales are forecasted to reach $800 billion in 2017 making it one of the biggest industries in the U.S. As of...

  15. Otur app

    DEFF Research Database (Denmark)

    2017-01-01

    HistorieLab har i samarbejde med firmaet ActVisual udviklet en app til mobilen, der giver mulighed for både at oprette og prøve andres opgaveruter rundt i landet. Såvel tekster som billeder lægges ind af brugerne.Brugerne kan således både blive formidlere og medproducenter af bl.a. historie....

  16. Hippocampal network oscillations in APP/APLP2-deficient mice.

    Directory of Open Access Journals (Sweden)

    Xiaomin Zhang

    Full Text Available The physiological function of amyloid precursor protein (APP and its two homologues APP-like protein 1 (APLP1 and 2 (APLP2 is largely unknown. Previous work suggests that lack of APP or APLP2 impairs synaptic plasticity and spatial learning. There is, however, almost no data on the role of APP or APLP at the network level which forms a critical interface between cellular functions and behavior. We have therefore investigated memory-related synaptic and network functions in hippocampal slices from three lines of transgenic mice: APPsα-KI (mice expressing extracellular fragment of APP, corresponding to the secreted APPsα ectodomain, APLP2-KO, and combined APPsα-KI/APLP2-KO (APPsα-DM for "double mutants". We analyzed two prominent patterns of network activity, gamma oscillations and sharp-wave ripple complexes (SPW-R. Both patterns were generally preserved in all strains. We find, however, a significantly reduced frequency of gamma oscillations in CA3 of APLP2-KO mice in comparison to APPsα-KI and WT mice. Network activity, basic synaptic transmission and short-term plasticity were unaltered in the combined mutants (APPsα-DM which showed, however, reduced long-term potentiation (LTP. Together, our data indicate that APLP2 and the intracellular domain of APP are not essential for coherent activity patterns in the hippocampus, but have subtle effects on synaptic plasticity and fine-tuning of network oscillations.

  17. Apps Developed by Academics

    Science.gov (United States)

    Shing, Sophia; Yuan, Benjamin

    2016-01-01

    In the days of the digital Wild West, developers from all backgrounds have joined in the gold rush trying to profit from the almost unbridled spending of well-to-do parents on educational products. In 2016, the Apple App Store had over 80,000 educational apps. The proliferation of educational apps has happened at a furious pace and more apps are…

  18. Smartphone apps for snoring.

    Science.gov (United States)

    Camacho, M; Robertson, M; Abdullatif, J; Certal, V; Kram, Y A; Ruoff, C M; Brietzke, S E; Capasso, R

    2015-10-01

    To identify and systematically evaluate user-friendly smartphone snoring apps. The Apple iTunes app store was searched for snoring apps that allow recording and playback. Snoring apps were downloaded, evaluated and rated independently by four authors. Two patients underwent polysomnography, and the data were compared with simultaneous snoring app recordings, and one patient used the snoring app at home. Of 126 snoring apps, 13 met the inclusion and exclusion criteria. The most critical app feature was the ability to graphically display the snoring events. The Quit Snoring app received the highest overall rating. When this app's recordings were compared with in-laboratory polysomnography data, app snoring sensitivities ranged from 64 to 96 per cent, and snoring positive predictive values ranged from 93 to 96 per cent. A chronic snorer used the app nightly for one month and tracked medical interventions. Snoring decreased from 200 to 10 snores per hour, and bed partner snoring complaint scores decreased from 9 to 2 (on a 0-10 scale). Select smartphone apps are user-friendly for recording and playing back snoring sounds. Preliminary comparison of more than 1500 individual snores demonstrates the potential clinical utility of such apps; however, further validation testing is recommended.

  19. Best Android Apps

    CERN Document Server

    Hendrickson, Mike

    2010-01-01

    You can choose from thousands of apps to make your Android device do just about anything you can think of -- and probably a few things you'd never imagine. There are so many Android apps available, in fact, that it's been difficult to find the best of the bunch -- until now. Best Android Apps leads you beyond the titles in Android Market's "Top Paid" and "Top Free" bins to showcase apps that will truly delight, empower, and entertain you. The authors have tested and handpicked more than 200 apps and games, each listed with a description and details highlighting the app's valuable tips and sp

  20. Smartphone apps for urolithiasis.

    Science.gov (United States)

    Stevens, D J; McKenzie, K; Cui, H W; Noble, J G; Turney, B W

    2015-02-01

    There are an increasing number of healthcare smartphone applications ('apps') available. Urolithiasis presents a major healthcare burden. Patients are increasingly keen to educate themselves regarding the diagnosis and management of their condition. There is no formal regulation of healthcare apps, including a large number of apps relating to urolithiasis. This review aims to examine the range of apps available, and the prevalence of healthcare professional input. Four international smartphone app stores were searched: Apple's App Store, Google Play (Android), BlackBerry App World and the Windows Phone App store. A total of 42 unique apps were downloaded and analysed. Recorded data included the cost (£/$), publisher information, number of ratings, average rating and any documentation of medical professional involvement. Twenty-one (50%) apps required payment for download. The mean cost was £3.58 ($6.04) with range £0.61-£34.90 ($1.03-$58.87). Thirty-three (79%) of the 42 apps were designed to be used by patients. Fifteen (36%) of the 42 apps had clear input from health professionals. Twenty-two apps offered patient information, including dietary advice on lowering calcium intake, which is contrary to current evidence-based practice. We conclude that urolithiasis apps have future potential to inform both patients and healthcare professionals on stone management. However, inaccuracies in the recommendations made by some apps can be misleading or even harmful due to a lack of specialist involvement. We recommend improving the usefulness of these apps by seeking a 'quality stamp' from recognised urological organisations and greater clinician involvement in future app development.

  1. Structural features of the KPI domain control APP dimerization, trafficking, and processing.

    Science.gov (United States)

    Ben Khalifa, Naouel; Tyteca, Donatienne; Marinangeli, Claudia; Depuydt, Mathieu; Collet, Jean-François; Courtoy, Pierre J; Renauld, Jean-Christophe; Constantinescu, Stefan; Octave, Jean-Noël; Kienlen-Campard, Pascal

    2012-02-01

    The two major isoforms of human APP, APP695 and APP751, differ by the presence of a Kunitz-type protease inhibitor (KPI) domain in the extracellular region. APP processing and function is thought to be regulated by homodimerization. We used bimolecular fluorescence complementation (BiFC) to study dimerization of different APP isoforms and mutants. APP751 was found to form significantly more homodimers than APP695. Mutation of dimerization motifs in the TM domain did not affect fluorescence complementation, but native folding of KPI is critical for APP751 homodimerization. APP751 and APP695 dimers were mostly localized at steady state in the Golgi region, suggesting that most of the APP751 and 695 dimers are in the secretory pathway. Mutation of the KPI led to the retention of the APP homodimers in the endoplasmic reticulum. We finally showed that APP751 is more efficiently processed through the nonamyloidogenic pathway than APP695. These findings provide new insight on the particular role of KPI domain in APP dimerization. The correlation observed between dimerization, subcellular localization, and processing suggests that dimerization acts as an efficient regulator of APP trafficking in the secretory compartments that has major consequences on its processing.

  2. Google Apps zijn leuk

    NARCIS (Netherlands)

    den Hollander, Franciscus

    Het bericht dat de Rijksuniversiteit Groningen overgaat op de mailvoorziening en agenda van Google Apps for Education bracht een golf van publiciteit teweeg. Mediaberichten naar aanleiding van de overgang naar Google Apps.

  3. Google App Inventor

    CERN Document Server

    Roberts, Ralph

    2011-01-01

    This book is written in the Beginner's Guide format that takes the reader through a series of steps to build exciting apps using Google's App Inventor. This book is perfect for people with little or no experience, not just Android developers. No matter your level of experience, you will find plenty of information that you can use to create powerful apps, apps that can be published on Android Market and other places.

  4. Mobile health apps in Sweden: what do physicians recommend?

    Science.gov (United States)

    Zhang, Yiping; Koch, Sabine

    2015-01-01

    Currently over 50,000 mobile health apps are available worldwide. In general, they are considered as innovations potentially delivering benefits to patients. Physicians are considered as potential channels to disseminate these innovations to patients. However, physicians' behavior in this regard has not been studied. To capture physicians' attitudes towards recommending health apps to patients and to describe factors influencing physicians' behavior, taking the specifics of an early adopter country, Sweden, into account. Diffusion of Innovation theory, the Health App Maturity Model and the Six Hurdles Model were used to construct a web-based survey that was answered by 44 Swedish physicians. Survey results were followed up with 2 individual interviews. Descriptive statistics were used for quantitative data analysis and recursive abstraction for qualitative data analysis. Only a small group of physicians currently recommend mobile health apps to their patients. However, most physicians have a positive attitude and perceive improvement of patients' self-management ability as main benefit of health apps. Main perceived weaknesses include the lack of evidence-based content and lack of multi-language support. Regulation of health apps under the Medical Device Directive is asked for to assure quality and patient safety. Innovators and early adopters play an important role in the diffusion of mobile health apps. Interpersonal communication is seen as the most effective way for physicians gaining information and also motivates them to recommend mobile health apps to their patients. Physicians' knowledge about certified websites to ensure quality is however low.

  5. Android apps security

    CERN Document Server

    Gunasekera, Sheran

    2012-01-01

    Android Apps Security provides guiding principles for how to best design and develop Android apps with security in mind. It explores concepts that can be used to secure apps and how developers can use and incorporate these security features into their apps. This book will provide developers with the information they need to design useful, high-performing, and secure apps that expose end-users to as little risk as possible.  Overview of Android OS versions, features, architecture and security.  Detailed examination of areas where attacks on applications can take place and what controls should b

  6. Light-induced flipping of a conserved glutamine sidechain and its oreintation in the AppA BLUF domain

    NARCIS (Netherlands)

    Grinstead, J.S.; Avila-Perez, M.; Hellingwerf, K.J.; Boelens, R.; Kaptein, R.

    2006-01-01

    The AppA BLUF domain is a blue light photoreceptor containing flavin. Conserved glutamine 63 is necessary for the photocycle of the protein, and its side chain has been proposed to flip in response to blue light illumination. Recently published crystal structures of AppA WT and the AppA mutant C20S

  7. Learning Discloses Abnormal Structural and Functional Plasticity at Hippocampal Synapses in the APP23 Mouse Model of Alzheimer's Disease

    Science.gov (United States)

    Middei, Silvia; Roberto, Anna; Berretta, Nicola; Panico, Maria Beatrice; Lista, Simone; Bernardi, Giorgio; Mercuri, Nicola B.; Ammassari-Teule, Martine; Nistico, Robert

    2010-01-01

    B6-Tg/Thy1APP23Sdz (APP23) mutant mice exhibit neurohistological hallmarks of Alzheimer's disease but show intact basal hippocampal neurotransmission and synaptic plasticity. Here, we examine whether spatial learning differently modifies the structural and electrophysiological properties of hippocampal synapses in APP23 and wild-type mice. While…

  8. Design for children's apps

    OpenAIRE

    MORANTE BONET, MIRIAM; Costa Ferrer, María; Rodríguez Calatayud, María Nuria

    2017-01-01

    Are children under 2 years old exposed to apps? Which ones? How often? What kind of apps would be best suited for small children based on their physical and cognitive development, the evolution of their play patterns and their ability to interact with mobile devices? How to design apps as appropriate as possible for children under 2 years old? These are some of the main questions that are answered through the research presented in this publication. An investigation that demonstra...

  9. Programming Google App Engine

    CERN Document Server

    Sanderson, Dan

    2010-01-01

    As one of today's cloud computing services, Google App Engine does more than provide access to a large system of servers. It also offers you a simple model for building applications that scale automatically to accommodate millions of users. With Programming Google App Engine, you'll get expert practical guidance that will help you make the best use of this powerful platform. Google engineer Dan Sanderson shows you how to design your applications for scalability, including ways to perform common development tasks using App Engine's APIs and scalable services. You'll learn about App Engine's a

  10. Apps for Ancient Civilizations

    Science.gov (United States)

    Thompson, Stephanie

    2011-01-01

    This project incorporates technology and a historical emphasis on science drawn from ancient civilizations to promote a greater understanding of conceptual science. In the Apps for Ancient Civilizations project, students investigate an ancient culture to discover how people might have used science and math smartphone apps to make their lives…

  11. Mobile Apps for Librarians

    Science.gov (United States)

    Power, June L.

    2013-01-01

    In an increasing mobile environment, library and reading-related activities often take place on a phone or tablet device. Not only does this mean that library Web sites must keep mobile navigability in mind, but also develop and utilize apps that allow patrons to interact with information and with libraries. While apps do not serve every purpose,…

  12. Sencha Architect app development

    CERN Document Server

    Groner, Loiane

    2013-01-01

    A standard tutorial-based approach for using Sencha Architect to develop applications in Ext JS and Sencha Touch.Sencha Architect App Development is for Ext JS and Sencha Touch developers that are looking to improve their productivity by using Sencha Architect for app development. Basic knowledge of Ext JS and Sencha Touch is required.

  13. Intracellular APP Sorting and Aβ Secretion are Regulated by Src-mediated Phosphorylation of Mint2

    Science.gov (United States)

    Chaufty, Jeremy; Sullivan, Sarah E.; Ho, Angela

    2012-01-01

    Mint adaptor proteins bind to the membrane-bound amyloid precursor protein (APP) and affect the production of pathogenic amyloid-beta (Aβ) peptides related to Alzheimer’s disease (AD). Previous studies have shown that loss of each of the three Mint proteins delays the age-dependent production of amyloid plaques in transgenic mouse models of AD. However, the cellular and molecular mechanisms underlying Mints effect on amyloid production are unclear. Because Aβ generation involves the internalization of membrane-bound APP via endosomes and Mints bind directly to the endocytic motif of APP, we proposed that Mints are involved in APP intracellular trafficking, which in turn, affects Aβ generation. Here, we show that APP endocytosis was attenuated in Mint knockout neurons, revealing a role for Mints in APP trafficking. We also show that the endocytic APP sorting processes are regulated by Src-mediated phosphorylation of Mint2 and that internalized APP is differentially sorted between autophagic and recycling trafficking pathways. A Mint2 phospho-mimetic mutant favored endocytosis of APP along the autophagic sorting pathway leading to increased intracellular Aβ accumulation. Conversely, the Mint2 phospho-resistant mutant increased APP localization to the recycling pathway and back to the cell surface thereby enhancing Aβ42 secretion. These results demonstrate that Src-mediated phosphorylation of Mint2 regulates the APP endocytic sorting pathway, providing a mechanism for regulating Aβ secretion. PMID:22787047

  14. Health Apps and How to Market Them

    OpenAIRE

    Hillenbrand, Susanna

    2016-01-01

    In future health apps may become as popular as mobile games and retail shopping apps. Some consumers even think that health app usage is more valuable than making or receiving calls. This multibillion industry of mobile software applications and especially health apps is relatively new. The main research topic was how to market health apps globally. Health apps like fitness, weight loss and wellness apps are new trend in apps business. Healthcare apps are divided into health- and medical apps...

  15. Akut ultralyd App

    DEFF Research Database (Denmark)

    Todsen, Tobias; Graumann, Ole; Laursen, Christian B.

    2015-01-01

    Denne app indeholder gennemgang af en række standardiserede ultralydsprotokoller, der kan udføres i forbindelse med undersøgelsen af den akutte patient til besvarelse af binære kliniske spørgsmål. App'en er blevet udviklet i et samarbejde mellem Københavns Universitet, Syddansk Universitet og...... Aarhus Universitet. Projektgruppen repræsenterer læger fra forskellige specialer og har alle beskæftiget sig med undervisning og forskning i klinisk ultralyd. App´en er gratis og kan hestes her: http://akutul.cekuapp.dk/...

  16. Apps for hearing healthcare.

    Science.gov (United States)

    Paglialonga, Alessia; Tognola, Gabriella; Pinciroli, Francesco

    2015-01-01

    The hearing healthcare scenario is rapidly evolving due to the pervasive use of m-Health solutions, in particular mobile apps. This brings along significant advantages and opportunities (e.g., accessibility, affordability, personalized healthcare, patient empowerment) as well as significant potential risks and threats (e.g., safety, misuse, quality issues, privacy). Our research aims at the identification and assessment of apps in the hearing healthcare domain. In this article we present an overview of the current availability, variety, and penetration of hearing-related apps.

  17. Using Google App Engine

    CERN Document Server

    Severance, Charles

    2009-01-01

    Build exciting, scalable web applications quickly and confidently using Google App Engine and this book, even if you have little or no experience in programming or web development. App Engine is perhaps the most appealing web technology to appear in the last year, providing an easy-to-use application framework with basic web tools. While Google's own tutorial assumes significant experience, Using Google App Engine will help anyone get started with this platform. By the end of this book, you'll know how to build complete, interactive applications and deploy them to the cloud using the same s

  18. Politics, pleasure, violence: Swedish defence propaganda in social media

    Directory of Open Access Journals (Sweden)

    Rodrigo Ferrada Stoehrel

    2013-10-01

    Full Text Available In recent years, the Swedish Armed Forces have produced and distributed highly edited video clips on YouTube that show moving images of military activity. Alongside this development, mobile phone apps have emerged as an important channel through which the user can experience and take an interactive part in the staging of contemporary armed conflict. This article examines the way in which the aesthetic and affective experience of Swedish defence and security policy is socially and (media-culturally (co-constructed and how the official representation of Swedish military intervention (reproduces political and economic effects when these activities are distributed through traditional and social media such as YouTube and digital apps. Based on Isabela and Norman Fairclough’s thoughts on political discourse, Michel Foucault’s dialectic idea of power/knowledge, and Sara Ahmed’s concept of the affective, I discuss how the Swedish digital military aesthetic is part of a broader political and economic practice which has consequences beyond the digital, the semiotic and what might at first glance appear to be pure entertainment. 

  19. Politics, pleasure, violence: Swedish defence propaganda in social media

    Directory of Open Access Journals (Sweden)

    Rodrigo Ferrada Stoehrel

    2013-12-01

    Full Text Available In recent years, the Swedish Armed Forces have produced and distributed highly edited video clips on YouTube that show moving images of military activity. Along- side this development, mobile phone apps have emerged as an important channel through which the user can experience and take an interactive part in the staging of contemporary armed conflict. This article examines the way in which the aes- thetic and affective experience of Swedish defence and security policy is socially and (media-culturally (co-constructed and how the official representation of Swedish military intervention (reproduces political and economic effects when these activi- ties are distributed through traditional and social media such as YouTube and digital apps. Based on Isabela and Norman Fairclough’s thoughts on political discourse, Michel Foucault’s dialectic idea of power/knowledge, and Sara Ahmed’s concept of the affective, I discuss how the Swedish digital military aesthetic is part of a broader political and economic practice that has consequences beyond the digital, the semi- otic, and what might at first glance appear to be pure entertainment.

  20. ATM mutants

    Indian Academy of Sciences (India)

    First page Back Continue Last page Graphics. ATM mutants. ATM (Ataxia Telangiectasia Mutated). AT2BE and AT5B1 cells – fibroblast cell lines from Ataxia telangiectasia patients. Deletion mutants expressing truncated ATM protein which is inactive. Have been used in studies looking at the role of ATM in DNA damage ...

  1. The Cytoscape app article collection

    NARCIS (Netherlands)

    Pico, Alexander R.; Bader, Gary D.; Demchak, Barry; Guitart Pla, Oriol; Hull, Timothy; Longabaugh, William; Lopes, Christian; Lotia, Samad; Molenaar, Piet; Montojo, Jason; Morris, John H.; Ono, Keiichiro; Schwikowski, Benno; Welker, David; Ideker, Trey

    2014-01-01

    As a network visualization and analysis platform, Cytoscape relies on apps to provide domain-specific features and functions. There are many resources available to support Cytoscape app development and distribution, including the Cytoscape App Store and an online "cookbook" for app developers. This

  2. Swedish Government Minister at CERN

    CERN Multimedia

    2008-01-01

    The Swedish Minister for Higher Education and Research recently visited CERN. The Swedish Minister was greeted by Swedish scientists working at CERN. Signing of the Swedish Computing Memorandum of Understanding. Pär Omling, Director-General of the Swedish Research Council (left), and Jos Engelen, CERN’s Chief Scientific Officer. Lars Leijonborg, the Swedish Minister for Higher Education and Research, was welcomed to CERN by Director-General Robert Aymar on 10 March. After an introduction to the Laboratory’s activities, the Minister was given guided tours of the control room, the ATLAS surface hall and experiment cavern and the adjoining LHC tunnel. Mr Leijonborg was then greeted by Swedish scientists and given an overview of the Swedish research programme at CERN. Five Swedish university groups are taking part in LHC research. Swedish universities are notably involved in the manufacture of parts for the sub-detectors of AT...

  3. The World of Orthodontic apps.

    Directory of Open Access Journals (Sweden)

    Gaurav Gupta

    2017-01-01

    Full Text Available The usage of the portable electronic devices such as the smartphones and handheld tablets has increased over the years, and this is true in the health-care industry also. This is because of the development of various patient management softwares. The use of apps to manage, educate, and inform patient is not uncommon among orthodontists nowadays. The aim of this article was to review the various apps available on the Google Play Store and iOS Apple Store for orthodontists and patients. Four smartphones using orthodontically relevant keywords such as orthodontics, orthodontists, and braces were searched and reviewed in detail. Out of the 354 orthodontically relevant apps available in both Android and Apple operating systems, the apps could be categorized as orthodontist-related apps or patient-related apps. Under these categories they could be further classified as practice managements apps, patient education apps, model analysis apps, tooth material calculators, patient reminder apps, etc.

  4. Altmetrics: An App Review

    OpenAIRE

    Konkiel, Stacy

    2012-01-01

    In a university culture increasingly influenced by metrics, academic libraries can use altmetrics to highlight scholarship's hidden value. This session will cover the apps and services that can help faculty, administration, and librarians learn the full, true impact of research.

  5. Apps I Have Loved

    Science.gov (United States)

    Schaffhauser, Dian

    2011-01-01

    According to a March estimate from Distimo, there were 653,614 apps in the iPhone, Android, iPad, BlackBerry, and Windows Mobile stores alone. So, is it any wonder that these busy people have found a few that come in handy on the job? Mobile apps are as indispensable to district IT executives as they are becoming in the classroom--for professional…

  6. Apps for Mathematics Learning: A Review of "Educational" Apps from the iTunes App Store

    Science.gov (United States)

    Highfield, Kate; Goodwin, Kristy

    2013-01-01

    Increasingly iPads™ are being used in schools and prior-to-school settings, with a plethora of Apps available for mathematics learning. Despite the growing number of Apps available in the iTunes App Store, there has been limited systematic analysis of the pedagogic design of Apps designed for mathematics learning. This paper describes a content…

  7. Designing apps for success developing consistent app design practices

    CERN Document Server

    David, Matthew

    2014-01-01

    In 2007, Apple released the iPhone. With this release came tools as revolutionary as the internet was to businesses and individuals back in the mid- and late-nineties: Apps. Much like websites drove (and still drive) business, so too do apps drive sales, efficiencies and communication between people. But also like web design and development, in its early years and iterations, guidelines and best practices for apps are few and far between.Designing Apps for Success provides web/app designers and developers with consistent app design practices that result in timely, appropriate, and efficiently

  8. Pro Android Apps Performance Optimization

    CERN Document Server

    Guihot, Hervé

    2012-01-01

    Today's Android apps developers are often running into the need to refine, improve and optimize their apps performances. As more complex apps can be created, it is even more important for developers to deal with this critical issue. Android allows developers to write apps using Java, C or a combination of both with the Android SDK and the Android NDK. Pro Android Apps Performance Optimization reveals how to fine-tune your Android apps, making them more stable and faster. In this book, you'll learn the following: * How to optimize your Java code with the SDK, but also how to write and optimize

  9. Instant AppFog

    CERN Document Server

    Wee, Pau Kiat

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This easy to follow, hands-on guide shows you how to deploy and manage your application within minutes.Instant AppFog Starter is great for developers who are new to AppFog and who are primarily working on code rather than infrastructure. This book is perfect for those who are looking to publish applications without an in-depth knowledge of servers, firewalls, and networking. It is assumed that you will have some experience of web development as

  10. Smartphone App for Voice Disorders

    Science.gov (United States)

    ... Feature: Taste, Smell, Hearing, Language, Voice, Balance Smartphone App for Voice Disorders Past Issues / Fall 2013 Table ... Center First to Study Minimally Verbal Children / Smartphone App for Voice Disorders / Stop the World from Spinning / ...

  11. There's an App for that!

    Science.gov (United States)

    Dutton, Gail

    2011-01-01

    Important as training the sales force is, mobile training apps are being used for much more. Visual Eyes Inc., for example, has developed training apps for the U.S. military's combat medical teams that detail specific medical procedures, such as controlling hemorrhaging. Other apps, developed for corporations and government agencies, pass along…

  12. Diet and Physical Activity Apps: Perceived Effectiveness by App Users

    Science.gov (United States)

    Egelandsdal, Bjørg; Amdam, Gro V; Almli, Valerie L; Oostindjer, Marije

    2016-01-01

    Background Diet and physical activity apps are two types of health apps that aim to promote healthy eating and energy expenditure through monitoring of dietary intake and physical activity. No clear evidence showing the effectiveness of using these apps to promote healthy eating and physical activity has been previously reported. Objective This study aimed to identify how diet and physical activity (PA) apps affected their users. It also investigated if using apps was associated with changes in diet and PA. Methods First, 3 semi-structured focus group discussions concerning app usability were conducted (15 app users and 8 nonusers; mean age 24.2 years, SD 6.4), including outcome measures such as motivations, experiences, opinions, and adherence. Results from the discussions were used to develop a questionnaire. The questionnaire, which contained questions about behavior changes, app usage, perceived effectiveness, and opinions of app usability, was answered by 500 Norwegians, with a mean age of 25.8 years (SD 5.1). Results App users found diet and PA apps effective in promoting healthy eating and exercising. These apps affected their actions, health consciousness, and self-education about nutrition and PA; and were also a part of their social lives. Over half of the users perceived that apps were effective in assisting them to eat healthily and to exercise more. Diet apps were more effective when they were frequently used and over a long period of time, compared to infrequent or short-term use (P=.01 and P=.02, respectively). Users who used diet and PA apps, perceived apps as more effective than users who only used one type of app (all PApp users were better at maintaining diet and PA behaviors than nonusers (all Papps fun to use, but sometimes time consuming. They wanted apps to be designed to meet their personal expectations. Conclusions App usage influenced action, consciousness, self-education about nutrition and PA, and social life. It facilitated maintaining

  13. CLAS App ML

    NARCIS (Netherlands)

    Maher, Bridget; Hartkopf, Kathleen; Stieger, Lina; Schroeder, Hanna; Sopka, Sasa; Orrego, Carola; Drachsler, Hendrik

    2014-01-01

    This is a multi-language (ML) update of the CLAS App original design by Bridget Maher from the School of Medicine at University College Cork, Ireland. The current version has an improve counting mechanism and has been translated from English to Spanish, Catalan and German languages within the

  14. The Swedish Model

    DEFF Research Database (Denmark)

    Kokko, Ari

    2012-01-01

    The main characteristics of ‘the Swedish model’ are arguably related to the country's knowledge-intensive industry and its advanced welfare state. The purpose of this chapter is to discuss the historical development of these two features of the Swedish economy. The first part looks at industrial...... development, highlighting both the reasons for the rapid industrialization in the late 19th century and the subsequent shift from raw materials to human capital and knowledge as the main competitive advantages. The second part turns to the development of welfare state, stressing the gradual increase...

  15. The Swedish financial system

    OpenAIRE

    Stenfors, Alexis; Clark, Eric; Farahani, Ilia; Hansen, Anders Lund; Passarella, Marco

    2014-01-01

    This study investigates the evolution of the Swedish financial system since the 1980s. The concept of financialisation, with its different elements and perspectives, is used as a lens through which the key historical developments are analysed. The aim of the study is two-fold. First, by highlighting some unique country-specific features, it addresses the profound changes that have taken place in the Swedish financial system during the last decades in relation to the ‘rise and fall’ of the so-...

  16. Oyster Fisheries App

    Science.gov (United States)

    Perez Guerrero, Geraldo A.; Armstrong, Duane; Underwood, Lauren

    2015-01-01

    This project is creating a cloud-enabled, HTML 5 web application to help oyster fishermen and state agencies apply Earth science to improve the management of this important natural and economic resource. The Oyster Fisheries app gathers and analyzes environmental and water quality information, and alerts fishermen and resources managers about problems in oyster fishing waters. An intuitive interface based on Google Maps displays the geospatial information and provides familiar interactive controls to the users. Alerts can be tailored to notify users when conditions in specific leases or public fishing areas require attention. The app is hosted on the Amazon Web Services cloud. It is being developed and tested using some of the latest web development tools such as web components and Polymer.

  17. Contemporary hernia smartphone applications (apps).

    Science.gov (United States)

    Connor, K; Brady, R R W; de Beaux, A; Tulloh, B

    2014-08-01

    Smartphone technology and downloadable applications (apps) have created an unprecedented opportunity for access to medical information and healthcare-related tools by clinicians and their patients. Here, we review the current smartphone apps in relation to hernias, one of the most common operations worldwide. This article presents an overview of apps relating to hernias and discusses content, the presence of medical professional involvement and commercial interests. The most widely used smartphone app online stores (Google Play, Apple, Nokia, Blackberry, Samsung and Windows) were searched for the following hernia-related terms: hernia, inguinal, femoral, umbilical, incisional and totally extraperitoneal. Those with no reference to hernia or hernia surgery were excluded. 26 smartphone apps were identified. Only 9 (35 %) had named medical professional involvement in their design/content and only 10 (38 %) were reviewed by consumers. Commercial interests/links were evident in 96 % of the apps. One app used a validated mathematical algorithm to help counsel patients about post-operative pain. There were a relatively small number of apps related to hernias in view of the worldwide frequency of hernia repair. This search identified many opportunities for the development of informative and validated evidence-based patient apps which can be recommended to patients by physicians. Greater regulation, transparency of commercial interests and involvement of medical professionals in the content and peer-review of healthcare-related apps is required.

  18. APP processing in Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Zhang Yun-wu

    2011-01-01

    Full Text Available Abstract An important pathological feature of Alzheimer's disease (AD is the presence of extracellular senile plaques in the brain. Senile plaques are composed of aggregations of small peptides called β-amyloid (Aβ. Multiple lines of evidence demonstrate that overproduction/aggregation of Aβ in the brain is a primary cause of AD and inhibition of Aβ generation has become a hot topic in AD research. Aβ is generated from β-amyloid precursor protein (APP through sequential cleavages first by β-secretase and then by γ-secretase complex. Alternatively, APP can be cleaved by α-secretase within the Aβ domain to release soluble APPα and preclude Aβ generation. Cleavage of APP by caspases may also contribute to AD pathologies. Therefore, understanding the metabolism/processing of APP is crucial for AD therapeutics. Here we review current knowledge of APP processing regulation as well as the patho/physiological functions of APP and its metabolites.

  19. Mobile Apps for Educational Purposes.

    Science.gov (United States)

    Pilcher, Jobeth

    With the growing number of mobile resources, nurse educators and professional development practitioners have the opportunity to harness mobile applications as a tool for their education toolbox. Yet, the overwhelming availability of choices can lead to questions, such as the following: How do we locate apps without spending huge amounts of our valuable time? How do we know which apps to choose? How can we evaluate apps? This article is aimed at addressing these questions.

  20. Swedish electricity market 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The organization of the Swedish electricity market has been in a state of continual change since the electricity market reform was started in the early 1990s. The conditions for the development of the electricity market have changed since the new Electricity Act came into force on 1 January 1996. The purpose of the reform is to introduce greater competition on the electricity market and provide the consumers with greater freedom of choice and, by open trade in electricity, to create the conditions for more efficient pricing. Being the central energy authority, the Swedish National Board for Industrial and Technical Development, NUTEK, was entrusted by the Government with the task of following developments on the Swedish electricity market. The Network Authority, which has the supervisory function for the new electricity market, were entrusted by the Government with the task of following developments on the Swedish electricity market and regularly compiling and reporting current market information. The new electricity market has now been operative for ten months. The Network Authority has submitted to the Government a detailed report entitled `Developments on the electricity market`, dealing with the experience gained from the electricity market reform. The purpose of the publication is to provide the players on the electricity market - the decision makers, the media and the general public - with comprehensive and easily accessible information on the market conditions. The publication includes summaries of information on electricity production and use in recent years, the structure of the electricity market from the perspective of a player, electricity trade in Sweden and in northern Europe, electricity prices in Sweden and other countries, and the impact of the electricity sector on the environment

  1. The swedish challenge

    International Nuclear Information System (INIS)

    Tregouet, R.

    2006-01-01

    Sweden decided to be the first country without petroleum for 2020. The author presents the major energy policy axis implemented by the swedish government to delete the part of the produced energy by the petroleum: development of the renewable energies, research programs of the transportation sector concerning the alternative fuels for the motors, energy efficiency and development of the biomass to replace the nuclear energy. (A.L.B.)

  2. Amazing Android Apps For Dummies

    CERN Document Server

    Begun, Daniel A

    2011-01-01

    Find the Android apps that are right for you so you can have fun and get more done!The popularity of Android apps is exploding and this handy guide helps you sort through the thousands of available applications so you can find the ones that are ideal for you. You'll explore a variety of apps in the areas of entertainment, finance, health, food, music, news, weather, photography, reference, dining out, social networking, sports, travel, and more. Author Daniel Begun helps you navigate through this enormous-and potentially overwhelming-array of Android apps.Holds your hand through the oftentimes

  3. Driver feedback mobile APP

    Energy Technology Data Exchange (ETDEWEB)

    Soriguera Marti, F.; Miralles Miquel, E.

    2016-07-01

    This paper faces the human factor in driving and its consequences for road safety. It presents the concepts behind the development of a smartphone app capable of evaluating drivers’ performance. The app provides feedback to the driver in terms of a grade (between 0 and 10) depending on the aggressiveness and risks taken while driving. These are computed from the cumulative probability distribution function of the jerks (i.e. the time derivative of acceleration), which are measured using the smartphones’ accelerometer. Different driving contexts (e.g. urban, freeway, congestion, etc.) are identified applying cluster analysis to the measurements, and treated independently. Using regression analysis, the aggressiveness indicator is related to the drivers' safety records and to the probability of having an accident, through the standard DBQ - Driving Behavior Questionnaire. Results from a very limited pilot test show a strong correlation between the 99th percentile of the jerk measurements and the DBQ results. A linear model is fitted. This allows quantifying the safe driving behavior only from smartphone measurements. Finally, this indicator is translated into a normalized grade and feedback to the driver. This feedback will challenge the driver to train and to improve his performance. The phone will be blocked while driving and will incorporate mechanisms to prevent bad practices, like competition in aggressive driving. The app is intended to contribute to the improvement of road safety, one of the major public health problems, by tackling the human factor which is the trigger of the vast majority of traffic accidents. Making explicit and quantifying risky behaviors is the first step towards a safer driving. (Author)

  4. Pro Java ME Apps

    CERN Document Server

    Iliescu, Ovidiu

    2011-01-01

    Pro Java ME Apps gives you, the developer, the know-how required for writing sophisticated Java ME applications and for taking advantage of this huge potential market. Java ME is the largest mobile software platform in the world, supported by over 80% of all phones. You'll cover what Java ME is and how it compares to other mobile software platforms, how to properly design and structure Java ME applications, how to think like an experienced Java ME developer, what common problems and pitfalls you may run into, how to optimize your code, and many other key topics. Unlike other Java ME books out

  5. The CLAS App - A training app to improve medical handovers

    NARCIS (Netherlands)

    Maher, Bridget; Drachsler, Hendrik; Kalz, Marco; Marcus, Specht

    2012-01-01

    Maher, B., Drachsler, H., Kalz, M., & Specht, M. (2012, 16-18 October). The CLAS App - A training app to improve medical handovers. Presentation at the 11th World Conference on Mobile and Contextual Learning, Helsinki, Finland. Please see also: http://hdl.handle.net/1820/4613

  6. Mobile apps in cardiology: review.

    Science.gov (United States)

    Martínez-Pérez, Borja; de la Torre-Díez, Isabel; López-Coronado, Miguel; Herreros-González, Jesús

    2013-07-24

    Cardiovascular diseases are the deadliest diseases worldwide, with 17.3 million deaths in 2008 alone. Among them, heart-related deaths are of the utmost relevance; a fact easily proven by the 7.25 million deaths caused by ischemic heart disease alone in that year. The latest advances in smartphones and mHealth have been used in the creation of thousands of medical apps related to cardiology, which can help to reduce these mortality rates. The aim of this paper is to study the literature on mobile systems and applications currently available, as well as the existing apps related to cardiology from the leading app stores and to then classify the results to see what is available and what is missing, focusing particularly on commercial apps. Two reviews have been developed. One is a literature review of mobile systems and applications, retrieved from several databases and systems such as Scopus, PubMed, IEEE Xplore, and Web of Knowledge. The other is a review of mobile apps in the leading app stores, Google play for Android and Apple's App Store for iOS. Search queries up to May 2013 located 406 papers and 710 apps related to cardiology and heart disease. The most researched section in the literature associated with cardiology is related to mobile heart (and vital signs) monitoring systems and the methods involved in the classification of heart signs in order to detect abnormal functions. Other systems with a significant number of papers are mobile cardiac rehabilitation systems, blood pressure measurement, and systems for the detection of heart failure. The majority of apps for cardiology are heart monitors and medical calculators. Other categories with a high number of apps are those for ECG education and interpretation, cardiology news and journals, blood pressure tracking, heart rate monitoring using an external device, and CPR instruction. There are very few guides on cardiac rehabilitation and apps for the management of the cardiac condition, and there were no

  7. Governance mechanisms for healthcare apps

    DEFF Research Database (Denmark)

    Manikas, Konstantinos; Hansen, Klaus Marius; Kyng, Morten

    2014-01-01

    The introduction of the `app store' concept has challenged the way software is distributed and marketed: developers have easier access to customers, while customers have easy access to innovative applications. Apps today are increasingly focusing on more "mission-critical" areas like healthcare w...

  8. Mobile Videoconferencing Apps for Telemedicine.

    Science.gov (United States)

    Zhang, Kai; Liu, Wei-Li; Locatis, Craig; Ackerman, Michael

    2016-01-01

    The quality and performance of several videoconferencing applications (apps) tested on iOS (Apple, Cupertino, CA) and Android (Google, Mountain View, CA) mobile platforms using Wi-Fi (802.11), third-generation (3G), and fourth-generation (4G) cellular networks are described. The tests were done to determine how well apps perform compared with videoconferencing software installed on computers or with more traditional videoconferencing using dedicated hardware. The rationale for app assessment and the testing methodology are described. Findings are discussed in relation to operating system platform (iOS or Android) for which the apps were designed and the type of network (Wi-Fi, 3G, or 4G) used. The platform, network, and apps interact, and it is impossible to discuss videoconferencing experienced on mobile devices in relation to one of these factors without referencing the others. Apps for mobile devices can vary significantly from other videoconferencing software or hardware. App performance increased over the testing period due to improvements in network infrastructure and how apps manage bandwidth.

  9. Best iPhone Apps

    CERN Document Server

    Biersdorfer, J

    2010-01-01

    With over 250,000 apps to choose from in Apple's App Store, you can make your iPhone or iPod Touch do just about anything you can imagine -- and almost certainly a few things you would never think of. While it's not hard to find apps, it is frustratingly difficult to find the the best ones. That's where this new edition of Best iPhone Apps comes in. New York Times technology columnist J.D. Biersdorfer has stress-tested hundreds of the App Store's mini-programs and hand-picked more than 200 standouts to help you get work done, play games, stay connected with friends, explore a new city, get i

  10. Your Life in Web Apps

    CERN Document Server

    Turnbull, Giles

    2008-01-01

    What is a web app? It's software that you use right in your web browser. Rather than installing an application on your computer, you visit a web site and sign up as a new user of its software. Instead of storing your files on your own hard disk, the web app stores them for you, online. Is it possible to switch entirely to web apps? To run nothing but a browser for an entire day? In this PDF we'll take you through one day in the life of a web apps-only user and chronicle the pros and cons of living by browser. And if the idea of switching, fully or partially, to web apps sounds appealing to

  11. Selecting "App"ealing and "App"ropriate Book Apps for Beginning Readers

    Science.gov (United States)

    Cahill, Maria; McGill-Franzen, Anne

    2013-01-01

    Beginning with a brief rationale for selecting quality digital picture book apps for beginning readers, the authors describe the elements of digital picture books and provide a brief review of the instructional benefits of digital picture book use for beginning readers. They then present a detailed taxonomy for selecting quality picture book apps.…

  12. Hybrid App Approach: Could It Mark the End of Native App Domination?

    OpenAIRE

    Minh Q. Huynh; Prashant Ghimire; Donny Truong

    2017-01-01

    Aim/Purpose: Despite millions of apps on the market, it is still challenging to develop a mobile app that can run across platforms using the same code. Background: This paper explores a potential solution for developing cross platform apps by presenting the hybrid app approach. Methodology: The paper first describes a brief evolution of the different mobile app development approaches and then compares them with the hybrid app approach. Next, it focuses on one specific hybrid app de...

  13. APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.

    Directory of Open Access Journals (Sweden)

    Melanie Laßek

    2016-04-01

    Full Text Available The hallmarks of Alzheimer's disease (AD are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the progression of AD is the hippocampal formation. The pathogenesis involves a successive loss of hippocampal neurons accompanied by a decline in learning and memory consolidation mainly attributed to an accumulation of senile plaques. The amyloid precursor protein (APP has been identified as precursor of Aβ-peptides, the main constituents of senile plaques. Until now, little is known about the physiological function of APP within the central nervous system. The allocation of APP to the proteome of the highly dynamic presynaptic active zone (PAZ highlights APP as a yet unknown player in neuronal communication and signaling. In this study, we analyze the impact of APP deletion on the hippocampal PAZ proteome. The native hippocampal PAZ derived from APP mouse mutants (APP-KOs and NexCreAPP/APLP2-cDKOs was isolated by subcellular fractionation and immunopurification. Subsequently, an isobaric labeling was performed using TMT6 for protein identification and quantification by high-resolution mass spectrometry. We combine bioinformatics tools and biochemical approaches to address the proteomics dataset and to understand the role of individual proteins. The impact of APP deletion on the hippocampal PAZ proteome was visualized by creating protein-protein interaction (PPI networks that incorporated APP into the synaptic vesicle cycle, cytoskeletal organization, and calcium-homeostasis. The combination of subcellular fractionation, immunopurification, proteomic analysis, and bioinformatics allowed us to identify APP as structural and functional regulator in a context-sensitive manner within the hippocampal active zone network.

  14. Y682 mutation of amyloid precursor protein promotes endo-lysosomal dysfunction by disrupting APP-SorLA interaction

    Directory of Open Access Journals (Sweden)

    Luca Rosario La Rosa

    2015-04-01

    Full Text Available The intracellular transport and localization of amyloid precursor protein (APP are critical determinants of APP processing and β-amyloid peptide production, thus crucially important for the pathophysiology of Alzheimer’s disease (AD. Notably, the C-terminal Y682ENPTY687 domain of APP binds to specific adaptors controlling APP trafficking and sorting in neurons. Mutation on the Y682 residue to glycine (Y682G leads to altered APP sorting in hippocampal neurons that favors its accumulation in intracellular compartments and the release of soluble APPα. Such alterations induce premature aging and learning and cognitive deficits in APP Y682G mutant mice (APPYG/YG. Here, we report that Y682G mutation affects formation of the APP complex with sortilin-related receptor (SorLA, resulting in endo-lysosomal dysfunctions and neuronal degeneration. Moreover, disruption of the APP/SorLA complex changes the trafficking pathway of SorLA, with its consequent increase in secretion outside neurons. Mutations in the SorLA gene are a prognostic factor in AD, and increases in SorLA levels in cerebrospinal fluid are predictive of AD in humans. These results might open new possibilities in comprehending the role played by SorLA in its interaction with APP and in the progression of neuronal degeneration. In addition, they further underline the crucial role played by Y682 residue in controlling APP trafficking in neurons.

  15. Android app development for dummies

    CERN Document Server

    Burton, Michael

    2015-01-01

    The updated edition of the bestselling guide to Android app development If you have ambitions to build an Android app, this hands-on guide gives you everything you need to dig into the development process and turn your great idea into a reality! In this new edition of Android App Development For Dummies, you'll find easy-to-follow access to the latest programming techniques that take advantage of the new features of the Android operating system. Plus, two programs are provided: a simple program to get you started and an intermediate program that uses more advanced aspects of the Android plat

  16. Be smart: Download the app!

    CERN Multimedia

    Katarina Anthony

    2013-01-01

    What’s the closest snack point to the CLIC test facility? How do you get from your current location to SM18? How do you enter the CERN Open Days photo contest? Finding out is simple: there’s an app for that!   The CERN Open Days app is your personal guide to the Laboratory. Developed by expert volunteers from the IT Department, the app provides comprehensive practical information on CERN transport, shops, snack points and toilet facilities along with detailed location information and event timetables. You can also favourite the sites, activities and lectures you plan to see, and tick them off as you go along. More information here.

  17. Mobile Apps for the Dietary Approaches to Stop Hypertension (DASH): App Quality Evaluation.

    Science.gov (United States)

    DiFilippo, Kristen Nicole; Huang, Wen-Hao David; Chapman-Novakofski, Karen M

    2018-03-08

    To identify the availability and quality of apps supporting Dietary Approaches to Stop Hypertension (DASH) education. The researchers identified DASH apps over 1 month in the Apple App Store. Five registered dietitians used the App Quality Evaluation (AQEL) to evaluate app quality on 7 domains. Interrater reliability was tested using intraclass correlations. One paid and 3 free DASH apps were evaluated. Interrater reliability (n = 5) was good for 3 apps and fair for 1 app. Only the paid app scored high (>8 of 10) on most AQEL quality domains. Based on lower quality found among the included free apps, further development of free apps is warranted. Whereas the paid app may be useful in supporting DASH education, future research should determine whether improvements in clinical outcomes are found and whether this app should be improved to address AQEL domains better. Copyright © 2018 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  18. Creating Innovative Student Projects with App Smashing

    Science.gov (United States)

    Young, Donna

    2014-01-01

    The potential for using various apps to improve student learning is tremendous. Yet, despite the iPad's possibilities, apps are often limited in their functionality. No one has created that magical, one-size-fits-all app that accomplishes all of the tasks that you had in mind. Luckily, there is an answer to this common problem: app smashing.…

  19. Gamification in Stress Management Apps: A Critical App Review

    Science.gov (United States)

    Christmann, Corinna A; Bleser, Gabriele

    2017-01-01

    Background In today’s society, stress is more and more often a cause of disease. This makes stress management an important target of behavior change programs. Gamification has been suggested as one way to support health behavior change. However, it remains unclear to which extend available gamification techniques are integrated in stress management apps, and if their occurrence is linked to the use of elements from behavior change theory. Objective The aim of this study was to investigate the use of gamification techniques in stress management apps and the cooccurrence of these techniques with evidence-based stress management methods and behavior change techniques. Methods A total of 62 stress management apps from the Google Play Store were reviewed on their inclusion of 17 gamification techniques, 15 stress management methods, and 26 behavior change techniques. For this purpose, an extended taxonomy of gamification techniques was constructed and applied by 2 trained, independent raters. Results Interrater-reliability was high, with agreement coefficient (AC)=.97. Results show an average of 0.5 gamification techniques for the tested apps and reveal no correlations between the use of gamification techniques and behavior change techniques (r=.17, P=.20), or stress management methods (r=.14, P=.26). Conclusions This leads to the conclusion that designers of stress management apps do not use gamification techniques to influence the user’s behaviors and reactions. Moreover, app designers do not exploit the potential of combining gamification techniques with behavior change theory. PMID:28592397

  20. Fabulous award for staffing app.

    Science.gov (United States)

    2015-12-02

    A safe staffing app giving up-to-date information on the number of nurses on the wards at Nottingham University Hospitals NHS Trust scooped top prize at the inaugural Academy of Fabulous NHS Stuffawards in London last week.

  1. Python for Google app engine

    CERN Document Server

    Pippi, Massimiliano

    2015-01-01

    If you are a Python developer, whether you have experience in web applications development or not, and want to rapidly deploy a scalable backend service or a modern web application on Google App Engine, then this book is for you.

  2. Swedish students' and preceptors' perceptions of what students learn in a six-month advanced pharmacy practice experience.

    Science.gov (United States)

    Wallman, Andy; Sporrong, Sofia Kälvemark; Gustavsson, Maria; Lindblad, Asa Kettis; Johansson, Markus; Ring, Lena

    2011-12-15

    To identify what pharmacy students learn during the 6-month advanced pharmacy practice experience (APPE) in Sweden. Semi-structured interviews were conducted with 18 pharmacy APPE students and 17 pharmacist preceptors and analyzed in a qualitative directed content analysis using a defined workplace learning typology for categories. The Swedish APPE provides students with task performance skills for work at pharmacies and social and professional knowledge, such as teamwork, how to learn while in a work setting, self-evaluation, understanding of the pharmacist role, and decision making and problem solving skills. Many of these skills and knowledge are not accounted for in the curricula in Sweden. Using a workplace learning typology to identify learning outcomes, as in this study, could be useful for curricula development. Exploring the learning that takes place during the APPE in a pharmacy revealed a broad range of skills and knowledge that students acquire.

  3. Instant Citrix XenApp

    CERN Document Server

    Mallett, Andrew

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This book is a great tool to quickly learn and explore the features offered by XenApp 6.5.Windows system administrators who want a quick lesson on how to install and configure XenApp.

  4. Swedish nuclear waste efforts

    Energy Technology Data Exchange (ETDEWEB)

    Rydberg, J.

    1981-09-01

    After the introduction of a law prohibiting the start-up of any new nuclear power plant until the utility had shown that the waste produced by the plant could be taken care of in an absolutely safe way, the Swedish nuclear utilities in December 1976 embarked on the Nuclear Fuel Safety Project, which in November 1977 presented a first report, Handling of Spent Nuclear Fuel and Final Storage of Vitrified Waste (KBS-I), and in November 1978 a second report, Handling and Final Storage of Unreprocessed Spent Nuclear Fuel (KBS II). These summary reports were supported by 120 technical reports prepared by 450 experts. The project engaged 70 private and governmental institutions at a total cost of US $15 million. The KBS-I and KBS-II reports are summarized in this document, as are also continued waste research efforts carried out by KBS, SKBF, PRAV, ASEA and other Swedish organizations. The KBS reports describe all steps (except reprocessing) in handling chain from removal from a reactor of spent fuel elements until their radioactive waste products are finally disposed of, in canisters, in an underground granite depository. The KBS concept relies on engineered multibarrier systems in combination with final storage in thoroughly investigated stable geologic formations. This report also briefly describes other activities carried out by the nuclear industry, namely, the construction of a central storage facility for spent fuel elements (to be in operation by 1985), a repository for reactor waste (to be in operation by 1988), and an intermediate storage facility for vitrified high-level waste (to be in operation by 1990). The R and D activities are updated to September 1981.

  5. The Ames Dwarf Mutation Attenuates Alzheimer’s Disease Phenotype of APP/PS1 mice

    Science.gov (United States)

    Puig, Kendra L.; Kulas, Joshua A.; Franklin, Whitney; Rakoczy, Sharlene G.; Taglialatela, Giulio; Brown-Borg, Holly M.; Combs, Colin K.

    2016-01-01

    APP/PS1 double transgenic mice expressing human mutant amyloid precursor protein (APP) and presenilin-1 (PS-1) demonstrate robust brain Aβ peptide containing plaque deposition, increased markers of oxidative stress, behavioral dysfunction, and proinflammatory gliosis. On the other hand, lack of growth hormone, prolactin, and thyroid-stimulating hormone due to a recessive mutation in the Prop 1 gene (Prop1df) in Ames dwarf mice results in a phenotype characterized by potentiated anti-oxidant mechanisms, improved learning and memory, and significantly increased longevity in homozygous mice. Based upon this, we hypothesized that a similar hormone deficiency might attenuate disease changes in the brains of APP/PS1 mice. To test this idea, APP/PS1 mice were crossed to the Ames dwarf mouse line. APP/PS1, wild type, df/+, df/df, df/+/APP/PS1, and df/df/APP/PS1 mice were compared at 6 months of age through behavioral testing and assessing amyloid burden, reactive gliosis, and brain cytokine levels. df/df mice demonstrated lower brain growth hormone (GH) and insulin-like growth factor 1 (IGF-1) concentrations. This correlated with decreased astrogliosis and microgliosis in the df/df/APP/PS1 mice and, surprisingly, reduced Aβ plaque deposition and Aβ 1-40 and Aβ 1-42 concentrations. The df/df/APP/PS1 mice also demonstrated significantly elevated brain levels of multiple cytokines in spite of the attenuated gliosis. These data indicate that the df/df/APP/PS1 line is a unique resource in which to study aging and resistance to disease and suggest that the affected pituitary hormones may have a role in regulating disease progression. PMID:26973101

  6. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease

    Science.gov (United States)

    Maulik, Mahua; Peake, Kyle; Chung, JiYun; Wang, Yanlin; Vance, Jean E.; Kar, Satyabrata

    2015-01-01

    Amyloid-β (Aβ) peptides originating from β-amyloid precursor protein (APP) are critical in Alzheimer's disease (AD). Cellular cholesterol levels/distribution can regulate production and clearance of Aβ peptides, albeit with contradictory outcomes. To better understand the relationship between cholesterol homeostasis and APP/Aβ metabolism, we have recently generated a bigenic ANPC mouse line overexpressing mutant human APP in the absence of Niemann-Pick type C-1 protein required for intracellular cholesterol transport. Using this unique bigenic ANPC mice and complementary stable N2a cells, we have examined the functional consequences of cellular cholesterol sequestration in the endosomal–lysosomal system, a major site of Aβ production, on APP/Aβ metabolism and its relation to neuronal viability. Levels of APP C-terminal fragments (α-CTF/β-CTF) and Aβ peptides, but not APP mRNA/protein or soluble APPα/APPβ, were increased in ANPC mouse brains and N2a-ANPC cells. These changes were accompanied by reduced clearance of peptides and an increased level/activity of γ-secretase, suggesting that accumulation of APP-CTFs is due to decreased turnover, whereas increased Aβ levels may result from a combination of increased production and decreased turnover. APP-CTFs and Aβ peptides were localized primarily in early-/late-endosomes and to some extent in lysosomes/autophagosomes. Cholesterol sequestration impaired endocytic-autophagic-lysosomal, but not proteasomal, clearance of APP-CTFs/Aβ peptides. Moreover, markers of oxidative stress were increased in vulnerable brain regions of ANPC mice and enhanced β-CTF/Aβ levels increased susceptibility of N2a-ANPC cells to H2O2-induced toxicity. Collectively, our results show that cellular cholesterol sequestration plays a key role in APP/Aβ metabolism and increasing neuronal vulnerability to oxidative stress in AD-related pathology. PMID:26433932

  7. Strategic analysis of Swedish agriculture

    OpenAIRE

    Fogelfors, Håkan; Wivstad, Maria; Eckersten, Henrik; Holstein, Fredrik; Johansson, Susanne; Verwijst, Theo

    2009-01-01

    This strategic analysis of Swedish agriculture – production systems and agricultural landscapes in a time of change – focuses on climate change, future availability of natural resources and economic regulation in a global food market. The background to the project was that the Faculty of Natural Resources and Agriculture of the Swedish University of Agricultural Sciences identified an urgent need to explore the implications and opportunities of coming changes for agricultural production syste...

  8. Mobile app reading speed test.

    Science.gov (United States)

    Kingsnorth, Alec; Wolffsohn, James S

    2015-04-01

    To validate the accuracy and repeatability of a mobile app reading speed test compared with the traditional paper version. Twenty-one subjects wearing their full refractive correction glasses read 14 sentences of decreasing print size between 1.0 and -0.1 logMAR, each consisting of 14 words (Radner reading speed test) at 40 cm with a paper-based chart and twice on iPad charts. Time duration was recorded with a stop watch for the paper chart and on the App itself for the mobile chart allowing critical print size (CPS) and optimal reading speed (ORS) to be derived objectively. The ORS was higher for the mobile app charts (194±29 wpm; 195±25 wpm) compared with the paper chart (166±20 wpm; F=57.000, pmobile app charts (0.17±0.20 logMAR; 0.18±0.17 logMAR) compared with the paper chart (0.25±0.17 logMAR; F=5.406, p=0.009). The mobile app test had a mean difference repeatability of 0.30±22.5 wpm, r=0.917 for ORS, and a CPS of 0.0±0.2 logMAR, r=0.769. Repeatability of the app reading speed test is as good (ORS) or better (CPS) than previous studies on the paper test. While the results are not interchangeable with paper-based charts, mobile app tablet-based tests of reading speed are reliable and rapid to perform, with the potential to capture functional visual ability in research studies and clinical practice. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  9. Psych-related iPhone apps.

    Science.gov (United States)

    Harrison, Anthony Mark; Goozee, Rhianna

    2014-02-01

    iPhone apps are a widely utilised technology that have recently been identified as a useful medium for health research, clinical interventions and education. While some researchers have discussed advances in app technology, others promote specific apps that are not free to access. To our knowledge, no study has conducted a review of current, free iPhone apps related to psychology, psychiatry and mental health. Therefore, we conducted a pilot, web-based review exploring free iPhone apps using a replicable search strategy within the iTunes Store search function. A selection of apps were selected and subjectively assessed in terms of their usability, utility, graphics, and associated costs for the consumer. We concluded that the apps reviewed, though novel, are limited in their scope and utility. We also note a significant gap in more scientific, evidence-based app technology, and pose some pertinent ethical questions when developing future psych-related apps.

  10. Obesity surgery smartphone apps: a review.

    Science.gov (United States)

    Stevens, Daniel J; Jackson, John A; Howes, Noah; Morgan, Justin

    2014-01-01

    The purpose of this study are to review available smartphone applications ('apps') relating to weight loss surgery, and assess the level of medical professional involvement in their design Smartphone apps relating to weight loss surgery were identified by searching the three app stores: Apple's App Store, Google Play (Android) and Blackberry AppWorld. A data search was undertaken using keywords and phrases relating to weight loss surgery. Apps designed for the non-surgical treatment of obesity were excluded. A total of 38 apps were identified (Google Play = 17, Apple App Store = 21, Blackberry World = 0). Ten of 38 apps were duplicated therefore 28 apps were reviewed. Mean app rating was 3.6/5 and mean app cost was £1.89. Twenty-six of 28 (92.9%) apps were designed for use by patients. Apps were categorised into the following categories: patient information (ten), patient support forums (six), patient record tools (six), weight loss clinic advertisements (four), a journal app (one) and a conference tool (one). Health professional involvement was evident in 12 of 28 (42.9%) apps. This study has identified that the majority of available apps relating to weight loss surgery do not have health professional input. The establishment of a 'quality stamp' provided by an established bariatric surgical body could improve the confidence with which patients and clinicians use these new information sources. Weight loss surgery apps offer a unique opportunity to provide accurate and reliable patient information and their use as part of the informed consent process should be explored.

  11. Gamification in Stress Management Apps: A Critical App Review.

    Science.gov (United States)

    Hoffmann, Alexandra; Christmann, Corinna A; Bleser, Gabriele

    2017-06-07

    In today's society, stress is more and more often a cause of disease. This makes stress management an important target of behavior change programs. Gamification has been suggested as one way to support health behavior change. However, it remains unclear to which extend available gamification techniques are integrated in stress management apps, and if their occurrence is linked to the use of elements from behavior change theory. The aim of this study was to investigate the use of gamification techniques in stress management apps and the cooccurrence of these techniques with evidence-based stress management methods and behavior change techniques. A total of 62 stress management apps from the Google Play Store were reviewed on their inclusion of 17 gamification techniques, 15 stress management methods, and 26 behavior change techniques. For this purpose, an extended taxonomy of gamification techniques was constructed and applied by 2 trained, independent raters. Interrater-reliability was high, with agreement coefficient (AC)=.97. Results show an average of 0.5 gamification techniques for the tested apps and reveal no correlations between the use of gamification techniques and behavior change techniques (r=.17, P=.20), or stress management methods (r=.14, P=.26). This leads to the conclusion that designers of stress management apps do not use gamification techniques to influence the user's behaviors and reactions. Moreover, app designers do not exploit the potential of combining gamification techniques with behavior change theory. ©Alexandra Hoffmann, Corinna A Christmann, Gabriele Bleser. Originally published in JMIR Serious Games (http://games.jmir.org), 07.06.2017.

  12. Swedish vineyards: a utopia?

    Directory of Open Access Journals (Sweden)

    Mårtensson A

    2013-07-01

    Full Text Available Anna Mårtensson,1 Thord Karlsson,2 Jan-Gunnar Gustafsson31Department of Soil and Environment, 2Department of Economics, Swedish University of Agricultural Sciences, Uppsala, Sweden; 3Bio Evaluation AB, Uppsala, SwedenAbstract: As there is an increasing interest for setting up vineyards and wineries in Sweden, a cost analysis is becoming necessary. In this study, we assessed the potential for wine production in Sweden. The estimated annual costs varied from €15.1/per L for production of 1800 L wine per ha to €41.9 for 525 L per ha. For an annual production of 1800 L per ha potentially achieved in an established vineyard, the capital requirement is €730,000. It would take 6 years for the investment to be paid off if the wine was sold for €37.5 per L. The high production costs mean that the only viable option for success is to orientate production towards the exclusive upper segment.Keywords: cold climate conditions, wine production costs, wine quality

  13. Swedish encapsulation station review

    International Nuclear Information System (INIS)

    Andersson, Sven Olof; Brunzell, P.; Heibel, R.; McCarthy, J.; Pennington, C.; Rusch, C.; Varley, G.

    1998-06-01

    In the Encapsulation Station (ES) Review performed by NAC International, a number of different areas have been studied. The main objectives with the review have been to: Perform an independent review of the cost estimates for the ES presented in SKB's document 'Plan 1996'. This has been made through comparisons between the ES and BNFL's Waste Encapsulation Plant (WEP) at Sellafield as well as with the CLAB facility. Review the location of the ES (at the CLAB site or at the final repository) and its interaction with other parts of the Swedish system for spent fuel management. Review the logistics and plant capacity of the ES. Identify important safety aspects of the ES as a basis for future licensing activities. Based on NAC International's experience of casks for transport and storage of spent fuel, review the basic design of the copper/steel canister and the transport cask. This review insides design, manufacturing, handling and licensing aspects. Perform an overall comparison between the ES project and the CLAB project with the objective to identify major project risks and discuss their mitigation

  14. Swedish encapsulation station review

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Sven Olof; Brunzell, P.; Heibel, R.; McCarthy, J.; Pennington, C.; Rusch, C.; Varley, G. [NAC International, Zuerich (Switzerland)

    1998-06-01

    In the Encapsulation Station (ES) Review performed by NAC International, a number of different areas have been studied. The main objectives with the review have been to: Perform an independent review of the cost estimates for the ES presented in SKB`s document `Plan 1996`. This has been made through comparisons between the ES and BNFL`s Waste Encapsulation Plant (WEP) at Sellafield as well as with the CLAB facility. Review the location of the ES (at the CLAB site or at the final repository) and its interaction with other parts of the Swedish system for spent fuel management. Review the logistics and plant capacity of the ES. Identify important safety aspects of the ES as a basis for future licensing activities. Based on NAC International`s experience of casks for transport and storage of spent fuel, review the basic design of the copper/steel canister and the transport cask. This review insides design, manufacturing, handling and licensing aspects. Perform an overall comparison between the ES project and the CLAB project with the objective to identify major project risks and discuss their mitigation 19 refs, 9 figs, 35 tabs

  15. Medication Adherence Apps: Review and Content Analysis.

    Science.gov (United States)

    Ahmed, Imran; Ahmad, Niall Safir; Ali, Shahnaz; Ali, Shair; George, Anju; Saleem Danish, Hiba; Uppal, Encarl; Soo, James; Mobasheri, Mohammad H; King, Dominic; Cox, Benita; Darzi, Ara

    2018-03-16

    Medication adherence is an expensive and damaging problem for patients and health care providers. Patients adhere to only 50% of drugs prescribed for chronic diseases in developed nations. Digital health has paved the way for innovative smartphone solutions to tackle this challenge. However, despite numerous apps available claiming to improve adherence, a thorough review of adherence apps has not been carried out to date. The aims of this study were to (1) review medication adherence apps available in app repositories in terms of their evidence base, medical professional involvement in development, and strategies used to facilitate behavior change and improve adherence and (2) provide a system of classification for these apps. In April 2015, relevant medication adherence apps were identified by searching the Apple App Store and the Google Play Store using a combination of relevant search terms. Data extracted included app store source, app price, documentation of health care professional (HCP) involvement during app development, and evidence base for each respective app. Free apps were downloaded to explore the strategies used to promote medication adherence. Testing involved a standardized medication regimen of three reminders over a 4-hour period. Nonadherence features designed to enhance user experience were also documented. The app repository search identified a total of 5881 apps. Of these, 805 fulfilled the inclusion criteria initially and were tested. Furthermore, 681 apps were further analyzed for data extraction. Of these, 420 apps were free for testing, 58 were inaccessible and 203 required payment. Of the 420 free apps, 57 apps were developed with HCP involvement and an evidence base was identified in only 4 apps. Of the paid apps, 9 apps had HCP involvement, 1 app had a documented evidence base, and 1 app had both. In addition, 18 inaccessible apps were produced with HCP involvement, whereas 2 apps had a documented evidence base. The 420 free apps were

  16. The Swedish Energy Market 2005

    International Nuclear Information System (INIS)

    2005-10-01

    The Swedish Energy Market, 2005 is an annual publication that presents information and statistics on the network based energy markets in Sweden, i.e. the markets for electricity, natural gas and district heating. It also provides an overview of the issues that have arisen on these markets during the second half of 2004 and the first half of 2005. Considerable work is being carried out in the EU on creating a single market for electricity and natural gas. This publication therefore describes expansion of the Swedish market towards a Nordic and a European market. The publication normally includes a theme chapter, describing some event of particular interest for the Swedish energy market during the year. This year, the theme chapter is devoted to the Storm Gudrun, which struck the south of the country at the beginning of January, and its effects on electricity supply throughout the country. The chapter is based on the report submitted to the Government by the Energy Markets Inspectorate in the spring of 2005, and also includes a summary of the Inspectorate's proposals for measures to improve the security of electricity transmission. Energy in Sweden, which is another of the Swedish Energy Agency's annual publications, provides information and statistics on the development of the entire Swedish energy system

  17. The Swedish Energy Market 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-10-01

    The Swedish Energy Market, 2005 is an annual publication that presents information and statistics on the network based energy markets in Sweden, i.e. the markets for electricity, natural gas and district heating. It also provides an overview of the issues that have arisen on these markets during the second half of 2004 and the first half of 2005. Considerable work is being carried out in the EU on creating a single market for electricity and natural gas. This publication therefore describes expansion of the Swedish market towards a Nordic and a European market. The publication normally includes a theme chapter, describing some event of particular interest for the Swedish energy market during the year. This year, the theme chapter is devoted to the Storm Gudrun, which struck the south of the country at the beginning of January, and its effects on electricity supply throughout the country. The chapter is based on the report submitted to the Government by the Energy Markets Inspectorate in the spring of 2005, and also includes a summary of the Inspectorate's proposals for measures to improve the security of electricity transmission. Energy in Sweden, which is another of the Swedish Energy Agency's annual publications, provides information and statistics on the development of the entire Swedish energy system.

  18. Is the Swedish FRAX model appropriate for Swedish immigrants?

    Science.gov (United States)

    Johansson, H; Odén, A; Lorentzon, M; McCloskey, E; Kanis, J A; Harvey, N C; Karlsson, M K; Mellström, D

    2015-11-01

    The incidence of hip fracture in Sweden is substantially lower in immigrants than in the population born in Sweden. Thus, the use of a FRAX® model in immigrants overestimates the risk of fracture, and the use of country of origin-specific models may be more appropriate. Age-specific fracture and mortality rates vary between countries so that FRAX tools are country-specific. In the case of immigrants, it is not known whether the model for the original or the new country is most appropriate. The aim of this study was to compare the incidence of hip fractures in foreign-born and Swedish-born individuals residing in Sweden. We studied the incidence of hip fracture in all men and women aged 50 years or more in Sweden between 1987 and 2002. The population comprised 2.8 million Swedish-born and 270,000 foreign-born individuals. Incident hip fractures occurred in 239,842 Swedish-born and 12,563 foreign-born individuals. The hip fracture incidence rose with age for both groups and was higher for women than men amongst both Swedish-born and foreign-born individuals. The hip fracture incidence for the Swedish-born cohort was approximately twice that of immigrants. For example, at the age of 70 years, the annual hip fracture incidence (per 100,000) was 450 (95 % CI 446-454) for a Swedish-born woman and 239 (95 % CI 223-257) for a foreign-born woman at the time of immigration. The hip fracture incidence rose slowly with time from immigration (0.6 % per annum, 95 % CI 0.5-0.8 %) but remained significantly lower than for Swedish-born individuals even after 40 years of residence. The incidence of hip fracture in Sweden is substantially lower in immigrants than in the population native to Sweden. Although there was a small rise in age- and sex-specific incidence after immigration, the incidence remained markedly lower than that observed in Swedish-born individuals. Thus, the use of a FRAX model for Sweden will overestimate the risk of fracture for foreign-born individuals living

  19. Cannabis Mobile Apps: A Content Analysis.

    Science.gov (United States)

    Ramo, Danielle E; Popova, Lucy; Grana, Rachel; Zhao, Shirley; Chavez, Kathryn

    2015-08-12

    Mobile technology is pervasive and widely used to obtain information about drugs such as cannabis, especially in a climate of rapidly changing cannabis policy; yet the content of available cannabis apps is largely unknown. Understanding the resources available to those searching for cannabis apps will clarify how this technology is being used to reflect and influence cannabis use behavior. We investigated the content of 59 cannabis-related mobile apps for Apple and Android devices as of November 26, 2014. The Apple and Google Play app stores were searched using the terms "cannabis" and "marijuana." Three trained coders classified the top 20 apps for each term and each store, using a coding guide. Apps were examined for the presence of 20 content codes derived by the researchers. Total apps available for each search term were 124 for cannabis and 218 for marijuana in the Apple App Store, and 250 each for cannabis and marijuana on Google Play. The top 20 apps in each category in each store were coded for 59 independent apps (30 Apple, 29 Google Play). The three most common content areas were cannabis strain classification (33.9%), facts about cannabis (20.3%), and games (20.3%). In the Apple App Store, most apps were free (77%), all were rated "17+" years, and the average user rating was 3.9/5 stars. The most popular apps provided cannabis strain classifications (50%), dispensary information (27%), or general facts about cannabis (27%). Only one app (3%) provided information or resources related to cannabis abuse, addiction, or treatment. On Google Play, most apps were free (93%), rated "high maturity" (79%), and the average user rating was 4.1/5. The most popular app types offered games (28%), phone utilities (eg, wallpaper, clock; 21%) and cannabis food recipes (21%); no apps addressed abuse, addiction, or treatment. Cannabis apps are generally free and highly rated. Apps were most often informational (facts, strain classification), or recreational (games), likely

  20. Cannabis Mobile Apps: A Content Analysis

    Science.gov (United States)

    Popova, Lucy; Grana, Rachel; Zhao, Shirley; Chavez, Kathryn

    2015-01-01

    Background Mobile technology is pervasive and widely used to obtain information about drugs such as cannabis, especially in a climate of rapidly changing cannabis policy; yet the content of available cannabis apps is largely unknown. Understanding the resources available to those searching for cannabis apps will clarify how this technology is being used to reflect and influence cannabis use behavior. Objective We investigated the content of 59 cannabis-related mobile apps for Apple and Android devices as of November 26, 2014. Methods The Apple and Google Play app stores were searched using the terms “cannabis” and “marijuana.” Three trained coders classified the top 20 apps for each term and each store, using a coding guide. Apps were examined for the presence of 20 content codes derived by the researchers. Results Total apps available for each search term were 124 for cannabis and 218 for marijuana in the Apple App Store, and 250 each for cannabis and marijuana on Google Play. The top 20 apps in each category in each store were coded for 59 independent apps (30 Apple, 29 Google Play). The three most common content areas were cannabis strain classification (33.9%), facts about cannabis (20.3%), and games (20.3%). In the Apple App Store, most apps were free (77%), all were rated “17+” years, and the average user rating was 3.9/5 stars. The most popular apps provided cannabis strain classifications (50%), dispensary information (27%), or general facts about cannabis (27%). Only one app (3%) provided information or resources related to cannabis abuse, addiction, or treatment. On Google Play, most apps were free (93%), rated “high maturity” (79%), and the average user rating was 4.1/5. The most popular app types offered games (28%), phone utilities (eg, wallpaper, clock; 21%) and cannabis food recipes (21%); no apps addressed abuse, addiction, or treatment. Conclusions Cannabis apps are generally free and highly rated. Apps were most often informational

  1. mHealthApps: A Repository and Database of Mobile Health Apps.

    Science.gov (United States)

    Xu, Wenlong; Liu, Yin

    2015-03-18

    The market of mobile health (mHealth) apps has rapidly evolved in the past decade. With more than 100,000 mHealth apps currently available, there is no centralized resource that collects information on these health-related apps for researchers in this field to effectively evaluate the strength and weakness of these apps. The objective of this study was to create a centralized mHealth app repository. We expect the analysis of information in this repository to provide insights for future mHealth research developments. We focused on apps from the two most established app stores, the Apple App Store and the Google Play Store. We extracted detailed information of each health-related app from these two app stores via our python crawling program, and then stored the information in both a user-friendly array format and a standard JavaScript Object Notation (JSON) format. We have developed a centralized resource that provides detailed information of more than 60,000 health-related apps from the Apple App Store and the Google Play Store. Using this information resource, we analyzed thousands of apps systematically and provide an overview of the trends for mHealth apps. This unique database allows the meta-analysis of health-related apps and provides guidance for research designs of future apps in the mHealth field.

  2. Smartphone use in neurosurgery? APP-solutely!

    Science.gov (United States)

    Zaki, Michael; Drazin, Doniel

    2014-01-01

    Background: A number of smartphone medical apps have recently emerged that may be helpful for the neurosurgical patient, practitioner, and trainee. This study aims to review the current neurosurgery-focused apps available for the iPhone, iPad, and Android platforms as of December 2013. Methods: Two of the most popular smartphone app stores (Apple Store and Android Google Play Store) were surveyed for neurosurgery-focused apps in December 2013. Search results were categorized based on their description page. Data were collected on price, rating, app release date, target audience, and medical professional involvement in app design. A review of the top apps in each category was performed. Results: The search resulted in 111 unique apps, divided into these 7 categories: 16 (14%) clinical tools, 17 (15%) conference adjunct, 27 (24%) education, 18 (16%) literature, 15 (14%) marketing, 10 (9%) patient information, and 8 (7%) reference. The average cost of paid apps was $23.06 (range: $0.99-89.99). Out of the 111 apps, 71 (64%) were free, 48 (43%) had reviews, and 14 (13%) had more than 10 reviews. Seventy-three (66%) apps showed evidence of medical professional involvement. The number of apps being released every year has been increasing since 2009. Conclusions: There are a number of neurosurgery-themed apps available to all audiences. There was a lack of patient information apps for nonspinal procedures. Most apps did not have enough reviews to evaluate their quality. There was also a lack of oversight to validate the accuracy of medical information provided in these apps. PMID:25101208

  3. Evaluating Apps for Learning and Teaching

    Directory of Open Access Journals (Sweden)

    Diana Renee D Jonas-Dwyer

    2012-03-01

    Full Text Available A growing number of educators and students are adopting mobile devices and using applications (apps. There are often no formal guidelines to assist with evaluating apps. A review of the literature was conducted to determine relevant criteria that could be applied to evaluating apps. Relevant examples are included where appropriate. Evaluation criteria are offered to assist educators and students with determining the suitability of apps.

  4. The best 100 free apps for libraries

    CERN Document Server

    Hahn, Jim

    2013-01-01

    Librarian Jim Hahn has carefully culled the over 500,000 available apps down to the 100 that are the absolute best for day-in, day-out library services. The guide covers apps from both Apple and Android devices, including tablets. This guide is intended as an introduction for those with little or no app experience and for those wanting to know more about app uses for information access.

  5. Obstetric Thromboprophylaxis: The Swedish Guidelines

    Directory of Open Access Journals (Sweden)

    Pelle G. Lindqvist

    2011-01-01

    Full Text Available Obstetric thromboprophylaxis is difficult. Since 10 years Swedish obstetricians have used a combined risk estimation model and recommendations concerning to whom, at what dose, when, and for how long thromboprophylaxis is to be administrated based on a weighted risk score. In this paper we describe the background and validation of the Swedish guidelines for obstetric thromboprophylaxis in women with moderate-high risk of VTE, that is, at similar or higher risk as the antepartum risk among women with history of thrombosis. The risk score is based on major risk factors (i.e., 5-fold increased risk of thromboembolism. We present data on the efficacy of the model, the cost-effectiveness, and the lifestyle advice that is given. We believe that the Swedish guidelines for obstetric thromboprophylaxis aid clinicians in providing women at increased risk of VTE with effective and appropriate thromboprophylaxis, thus avoiding both over- and under-treatment.

  6. App Inventor for Android Build Your Own Apps - No Experience Required!

    CERN Document Server

    Tyler, Jason

    2011-01-01

    Create Android mobile apps, no programming required! Even with limited programming experience, you can easily learn to create apps for the Android platform with this complete guide to App Inventor for Android. App Inventor for Android is a visual language that relies on simple programming blocks that users can drag and drop to create apps. This handy book gives you a series of fully worked-out apps, complete with their programming blocks, which you can customize for your own use or use as a starting point for creating the next killer app. And it's all without writing a single line of code. Don

  7. Capitalizing on App Development Tools and Technologies

    Science.gov (United States)

    Luterbach, Kenneth J.; Hubbell, Kenneth R.

    2015-01-01

    Instructional developers and others creating apps must choose from a wide variety of app development tools and technologies. Some app development tools have incorporated visual programming features, which enable some drag and drop coding and contextual programming. While those features help novices begin programming with greater ease, questions…

  8. Citrix XenApp performance essentials

    CERN Document Server

    Dentella, Luca

    2013-01-01

    A practical hands-on tutorial including multiple examples on application management using Citrix XenApp 6.5.Citrix XenApp Performance Essentials is intended for IT architects and system administrators who work with Citrix XenApp and who need an agile, practical guide to tune and optimize the performance.

  9. Color Addition and Subtraction Apps

    Science.gov (United States)

    Ruiz, Frances; Ruiz, Michael J.

    2015-01-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step…

  10. Hybrid App Approach: Could It Mark the End of Native App Domination?

    Directory of Open Access Journals (Sweden)

    Minh Q. Huynh

    2017-04-01

    Full Text Available Aim/Purpose: Despite millions of apps on the market, it is still challenging to develop a mobile app that can run across platforms using the same code. Background: This paper explores a potential solution for developing cross platform apps by presenting the hybrid app approach. Methodology: The paper first describes a brief evolution of the different mobile app development approaches and then compares them with the hybrid app approach. Next, it focuses on one specific hybrid app development framework called Ionic. Contribution: The paper presents the hybrid app approach as an emerging trend in mobile app development and concludes with the highlight of its advantages and teaching implications. Findings: The hybrid app approach reduces the learning curve and offers tools to allow the reuse of code to create apps for different mobile devices. Recommendations for Practitioners: The experience that the paper describes in using Ionic framework to create a hybrid app can be adopted in a web design or mobile app development course. Impact on Society\t: The advance in hybrid framework in general and the growing acceptance of open source framework, such as Ionic in particular, may provide an alternative to the native app domination and may trigger the rapid rise of hybrid apps in the years to come.

  11. The Swedish Academy Dictionary Project

    African Journals Online (AJOL)

    rbr

    language, heavily influenced by Low German. During the period of Early Modern Swedish (1526–1732), several bilingual or multilingual dictionaries were written to facilitate the learning of other lan- guages, such as Latin, German, English and French. It also brought the first attempt at a descriptive monolingual dictionary of ...

  12. Apps of Steel: Are Exercise Apps Providing Consumers with Realistic Expectations?: A Content Analysis of Exercise Apps for Presence of Behavior Change Theory

    Science.gov (United States)

    Cowan, Logan T.; Van Wagenen, Sarah A.; Brown, Brittany A.; Hedin, Riley J.; Seino-Stephan, Yukiko; Hall, P. Cougar; West, Joshua H.

    2013-01-01

    Objective. To quantify the presence of health behavior theory constructs in iPhone apps targeting physical activity. Methods. This study used a content analysis of 127 apps from Apple's (App Store) "Health & Fitness" category. Coders downloaded the apps and then used an established theory-based instrument to rate each app's inclusion of…

  13. An over expression APP model for anti-Alzheimer disease drug screening created by zinc finger nuclease technology.

    Directory of Open Access Journals (Sweden)

    Xiaojing Zhang

    Full Text Available Zinc Finger Nucleases (ZFNs, famous for their ability to precisely and efficiently modify specific genomic loci, have been employed in numerous transgenic model organism and cell constructions. Here we employ the ZFNs technology, with homologous recombination (HR, to construct sequence-specific Amyloid Precursor Protein (APP knock-in cells. With the use of ZFNs, we established APP knock in cell lines with gene-modification efficiencies of about 7%. We electroporated DNA fragment containing the promoter and the protein coding regions of the zinc finger nucleases into cells, instead of the plasmids, to avoid problems associated with off target homologous recombination, and adopted a pair of mutated FokI cleavage domains to reduce the toxic effects of the ZFNs on cell growth. Since over-expression of APP, or a subdomain of it, might lead to an immediately lethal effect, we used the Cre-LoxP System to regulate APP expression. Our genetically transformed cell lines, w5c1 and s12c8, showed detectable APP and Amyloid β (Aβ production. The Swedish double mutation in the APP coding sequence enhanced APP and Aβ abundance. What is more, the activity of the three key secretases in Aβ formation could be modulated, indicating that these transgenic cells have potential for drug screening to modify amyloid metabolism in cells. Our transformed cells could readily be propagated in culture and should provide an excellent experimental medium for elucidating aspects of the molecular pathogenesis of Alzheimer's disease, especially those concerning the amyloidogenic pathways involving mutations in the APP coding sequence. The cellular models may also serve as a tool for deriving potentially useful therapeutic agents.

  14. Learning System Center App Controller

    CERN Document Server

    Naeem, Nasir

    2015-01-01

    This book is intended for IT professionals working with Hyper-V, Azure cloud, VMM, and private cloud technologies who are looking for a quick way to get up and running with System Center 2012 R2 App Controller. To get the most out of this book, you should be familiar with Microsoft Hyper-V technology. Knowledge of Virtual Machine Manager is helpful but not mandatory.

  15. Apps and intensive care medicine.

    Science.gov (United States)

    Iglesias-Posadilla, D; Gómez-Marcos, V; Hernández-Tejedor, A

    2017-05-01

    Technological advances have played a key role over the last century in the development of humankind. Critical Care Medicine is one of the greatest examples of this revolution. Smartphones with multiple sensors constitute another step forward, and have led to the development of apps for use by both professionals and patients. We discuss their main medical applications in the field of Critical Care Medicine. Copyright © 2017 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  16. Android App Store (Google Play) Mining and Analysis

    OpenAIRE

    MOHAMMAD TAFIQUR, RAHMAN

    2013-01-01

    The aim of mining and analysis of Apps in Google Play, the largest Android app store, is to provide in-depth insight on the hidden properties of the repository to app developers or app market contributors. This approach can help them to view the current circumstances of the market and make valuable decisions before releasing products. To perform this analysis, all available features (descriptions of the app, app developer information, app version, updating date, category, number of download, ...

  17. App Savvy Turning Ideas into iPad and iPhone Apps Customers Really Want

    CERN Document Server

    Yarmosh, Ken

    2010-01-01

    How can you make your iPad or iPhone app stand out in the highly competitive App Store? While many books simply explore the technical aspects of iPad and iPhone app design and development, App Savvy also focuses on the business, product, and marketing elements critical to pursuing, completing, and selling your app -- the ingredients for turning a great idea into a genuinely successful product. Whether you're a designer, developer, entrepreneur, or just someone with a unique idea, App Savvy explains every step in the process, with guidelines for planning a solid concept, engaging customers ea

  18. An Android Communication App Forensic Taxonomy.

    Science.gov (United States)

    Azfar, Abdullah; Choo, Kim-Kwang Raymond; Liu, Lin

    2016-09-01

    Due to the popularity of Android devices and applications (apps), Android forensics is one of the most studied topics within mobile forensics. Communication apps, such as instant messaging and Voice over IP (VoIP), are one popular app category used by mobile device users, including criminals. Therefore, a taxonomy outlining artifacts of forensic interest involving the use of Android communication apps will facilitate the timely collection and analysis of evidentiary materials from such apps. In this paper, 30 popular Android communication apps were examined, where a logical extraction of the Android phone images was collected using XRY, a widely used mobile forensic tool. Various information of forensic interest, such as contact lists and chronology of messages, was recovered. Based on the findings, a two-dimensional taxonomy of the forensic artifacts of the communication apps is proposed, with the app categories in one dimension and the classes of artifacts in the other dimension. Finally, the artifacts identified in the study of the 30 communication apps are summarized using the taxonomy. It is expected that the proposed taxonomy and the forensic findings in this paper will assist forensic investigations involving Android communication apps. © 2016 American Academy of Forensic Sciences.

  19. Palmitoylated APP Forms Dimers, Cleaved by BACE1

    Science.gov (United States)

    Fenn, Rebecca H.; Barren, Cory; Tanzi, Rudolph E.; Kovacs, Dora M.

    2016-01-01

    A major rate-limiting step for Aβ generation and deposition in Alzheimer’s disease brains is BACE1-mediated cleavage (β-cleavage) of the amyloid precursor protein (APP). We previously reported that APP undergoes palmitoylation at two cysteine residues (Cys186 and Cys187) in the E1-ectodomain. 8–10% of total APP is palmitoylated in vitro and in vivo. Palmitoylated APP (palAPP) shows greater preference for β-cleavage than total APP in detergent resistant lipid rafts. Protein palmitoylation is known to promote protein dimerization. Since dimerization of APP at its E1-ectodomain results in elevated BACE1-mediated cleavage of APP, we have now investigated whether palmitoylation of APP affects its dimerization and whether this leads to elevated β-cleavage of the protein. Here we report that over 90% of palAPP is dimerized while only ~20% of total APP forms dimers. PalAPP-dimers are predominantly cis-oriented while total APP dimerizes in both cis- and trans-orientation. PalAPP forms dimers 4.5-times more efficiently than total APP. Overexpression of the palmitoylating enzymes DHHC7 and DHHC21 that increase palAPP levels and Aβ release, also increased APP dimerization in cells. Conversely, inhibition of APP palmitoylation by pharmacological inhibitors reduced APP-dimerization in coimmunoprecipitation and FLIM/FRET assays. Finally, in vitro BACE1-activity assays demonstrate that palmitoylation-dependent dimerization of APP promotes β-cleavage of APP in lipid-rich detergent resistant cell membranes (DRMs), when compared to total APP. Most importantly, generation of sAPPβ-sAPPβ dimers is dependent on APP-palmitoylation while total sAPPβ generation is not. Since BACE1 shows preference for palAPP dimers over total APP, palAPP dimers may serve as novel targets for effective β-cleavage inhibitors of APP as opposed to BACE1 inhibitors. PMID:27875558

  20. Windows 8 app projects XAML and C#

    CERN Document Server

    Vermeir, Nico

    2013-01-01

    Become a leading Windows 8 app developer by using Windows 8 App Projects - XAML and C# Edition to learn techniques, tools, and ideas to create successful, 5-star apps. Windows 8 App Projects - XAML and C# Edition shows you the nuts and bolts of the Windows 8 development ecosystem. Then, through a series of example driven chapters, you'll discover how to leverage the platform's unique features. With each project, you'll be one step closer to building full-featured, responsive, and well designed apps that feel like they're a part of the operating system. Windows 8 App Projects - XAML and C# Edit

  1. Swedish mines. Underground exploitation methods

    International Nuclear Information System (INIS)

    Paucard, A.

    1960-01-01

    Between 1949 and 1957, 10 engineers of the Mining research and exploitation department of the CEA visited 17 Swedish mines during 5 field trips. This paper presents a compilation of the information gathered during these field trips concerning the different underground mining techniques used in Swedish iron mines: mining with backfilling (Central Sweden and Boliden mines); mining without backfilling (mines of the polar circle area). The following techniques are described successively: pillar drawing and backfilled slices (Ammeberg, Falun, Garpenberg, Boliden group), sub-level pillar drawing (Grangesberg, Bloettberget, Haeksberg), empty room and sub-level pillar drawing (Bodas, Haksberg, Stripa, Bastkarn), storage chamber pillar drawing (Bodas, Haeksberg, Bastkarn), and pillar drawing by block caving (ldkerberget). Reprint of a paper published in Revue de l'Industrie Minerale, vol. 41, no. 12, 1959 [fr

  2. Swedish minister rebuilds scientists' trust

    CERN Multimedia

    Sylwan, P

    1999-01-01

    Thomas Ostros, Sweden's new science minister is aiming to improve links with the science community, severely strained during the tenure of Carl Tham. Significantly, he confirmed that he will not be making any further changes to the managment of the Swedish Foundation for Strategic Research. He also announced a 5 per cent increase in government funding for science which will be used to strengthen basic research and education (1 page).

  3. Hypnosis: There’s an App for that. A systematic review of hypnosis apps

    Science.gov (United States)

    Sucala, Madalina; Schnur, Julie B.; Glazier, Kimberly; Miller, Sarah J.; Green, Joseph P.; Montgomery, Guy H.

    2013-01-01

    The study systematically reviews the hypnosis apps available via iTunes that were compatible with iPhone or iPad. Of 1455 apps identified on iTunes, 407 met inclusion criteria and were further reviewed. Most common hypnosis app targets were: weight loss (23%), boosting self-esteem (20%), and relaxation/stress reduction (19%). 83% of apps delivered hypnosis via audio track, and 37% allowed tailoring. Less than 14% of apps reported disclaimers. None of the apps reported having been tested for efficacy, and none reported being evidence-based. Although apps have the potential to enhance hypnosis delivery, it seems as though technology has raced ahead of the supporting science. Recommendations from clinical researchers and policy makers are needed to inform responsible hypnosis app development and use. PMID:23957263

  4. APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice

    Science.gov (United States)

    Choi, Hong Y; Liu, Yun; Tennert, Christian; Sugiura, Yoshie; Karakatsani, Andromachi; Kröger, Stephan; Johnson, Eric B; Hammer, Robert E; Lin, Weichun; Herz, Joachim

    2013-01-01

    ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP interacts with LRP4, an obligate co-receptor for muscle-specific tyrosine kinase (MuSK). Agrin, a ligand for LRP4, also binds to APP and co-operatively enhances the interaction of APP with LRP4. In cultured myotubes, APP synergistically increases agrin-induced acetylcholine receptor (AChR) clustering. Deletion of the transmembrane domain of LRP4 (LRP4 ECD) results in growth retardation of the NMJ, and these defects are markedly enhanced in APP−/−;LRP4ECD/ECD mice. Double mutant NMJs are significantly reduced in size and number, resulting in perinatal lethality. Our findings reveal novel roles for APP in regulating neuromuscular synapse formation through hetero-oligomeric interaction with LRP4 and agrin and thereby provide new insights into the molecular mechanisms that govern NMJ formation and maintenance. DOI: http://dx.doi.org/10.7554/eLife.00220.001 PMID:23986861

  5. Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).

    Science.gov (United States)

    Tesco, Giuseppina; Koh, Young Ho; Tanzi, Rudolph E

    2003-11-14

    The amyloid precursor protein (APP) undergoes "alternative" proteolysis mediated by caspases. Three major caspase recognition sites have been identified in the APP, i.e. one at the C terminus (Asp720) and two at the N terminus (Asp197 and Asp219). Caspase cleavage at Asp720 has been suggested as leading to increased production of Abeta. Thus, we set out to determine which putative caspase sites in APP, if any, are cleaved in Chinese hamster ovary cell lines concurrently with the increased Abeta production that occurs during apoptosis. We found that cleavage at Asp720 occurred concurrently with caspase 3 activation and the increased production of total secreted Abeta and Abeta1-42 in association with staurosporine- and etoposide-induced apoptosis. To investigate the contribution of caspase cleavage of APP to Abeta generation, we expressed an APP mutant truncated at Asp720 that mimics APP caspase cleavage at the C-terminal site. This did not increase Abeta generation but, in contrast, dramatically decreased Abeta production in Chinese hamster ovary cells. Furthermore, the ablation of caspase-dependent cleavage at Asp720, Asp197, and Asp219 (by site-directed mutagenesis) did not prevent enhanced Abeta production following etoposide-induced apoptosis. These findings indicate that the enhanced Abeta generation associated with apoptosis does not require cleavage of APP at its C-terminal (Asp720) and/or N-terminal caspase sites.

  6. Storybook app creation demystified a cast study

    CERN Document Server

    Friedlander, Amy

    2013-01-01

    This case study explains how Wasabi Productions created its first app, Lazy Larry Lizard, and provides insight into the development of soon-to-be-released app, Gorilla Band. Inside, you will find notes on how storybook apps are produced from start to finish, including costs, production process, people, technology, pricing, release cycle, marketing and more. You will also find insights on technology, storyboard development and pricing.

  7. Social gaming on the Spotify app platform

    OpenAIRE

    Jönsson, Martin

    2013-01-01

    Spotify wants to explore the possibilities of social gaming within their desktop client. Thanks to their Spotify Apps API it is possible to build applications that integrate with the Spotify library while using modern web technologies. This thesis work consists of exploring what is possible using the Spotify App API and the most modern web technologies available. The main theme and goal of the Spotify App is to engage users in a social context. Creating a quiz application, which users can pla...

  8. What Makes a Good App Description?

    OpenAIRE

    Jiang, He; Ma, Hongjing; Ren, Zhilei; Zhang, Jingxuan; Li, Xiaochen

    2017-01-01

    In the Google Play store, an introduction page is associated with every mobile application (app) for users to acquire its details, including screenshots, description, reviews, etc. However, it remains a challenge to identify what items influence users most when downloading an app. To explore users' perspective, we conduct a survey to inquire about this question. The results of survey suggest that the participants pay most attention to the app description which gives users a quick overview of ...

  9. Swedish earthquakes and acceleration probabilities

    International Nuclear Information System (INIS)

    Slunga, R.

    1979-03-01

    A method to assign probabilities to ground accelerations for Swedish sites is described. As hardly any nearfield instrumental data is available we are left with the problem of interpreting macroseismic data in terms of acceleration. By theoretical wave propagation computations the relation between seismic strength of the earthquake, focal depth, distance and ground accelerations are calculated. We found that most Swedish earthquake of the area, the 1904 earthquake 100 km south of Oslo, is an exception and probably had a focal depth exceeding 25 km. For the nuclear power plant sites an annual probability of 10 -5 has been proposed as interesting. This probability gives ground accelerations in the range 5-20 % for the sites. This acceleration is for a free bedrock site. For consistency all acceleration results in this study are given for bedrock sites. When applicating our model to the 1904 earthquake and assuming the focal zone to be in the lower crust we get the epicentral acceleration of this earthquake to be 5-15 % g. The results above are based on an analyses of macrosismic data as relevant instrumental data is lacking. However, the macroseismic acceleration model deduced in this study gives epicentral ground acceleration of small Swedish earthquakes in agreement with existent distant instrumental data. (author)

  10. Promising rice mutants

    International Nuclear Information System (INIS)

    Hakim, L.; Azam, M.A.; Miah, A.J.; Mansur, M.A.; Akanda, H.R.

    1988-01-01

    Two induced mutants namely, Mut NS 1 (tall) and Mut NS 5 (semi-dwarf) derived from rice variety Nizersail were evaluated for various agronomic characters at four locations in Bangladesh. Both the mutants matured about three weeks earlier and yielded significantly higher than the parent variety Nizersail. (author). 3 tabs., 9 refs

  11. Mutant heterosis in rice

    International Nuclear Information System (INIS)

    1987-01-01

    In the variety TKM6 a high yielding semidwarf mutant has been induced. This TKM6 mutant was used in test crosses with a number of other varieties and mutants to examine the extent of heterosis of dwarfs in rice and to select superior crosses. An excerpt of the published data is given. It appears from the backcross of the mutant with its original variety, that an increase in number of productive tillers occurs in the hybrid, leading to a striking grain yield increase, while the semi-dwarf culm length (the main mutant character) reverts to the normal phenotype. In the cross with IR8 on the other hand, there is only a minimal increase in tiller number but a substantial increase in TGW leading to more than 30% yield increase over the better parent

  12. Apps for Radiation Oncology. A Comprehensive Review

    Directory of Open Access Journals (Sweden)

    J.J. Calero

    2017-02-01

    Full Text Available Introduction: Software applications executed on a smart-phone or mobile device (“Apps” are increasingly used by oncologists in their daily work. A comprehensive critical review was conducted on Apps specifically designed for Radiation Oncology, which aims to provide scientific support for these tools and to guide users in choosing the most suited to their needs. Material and methods: A systematic search was conducted in mobile platforms, iOS and Android, returning 157 Apps. Excluding those whose purpose did not match the scope of the study, 31 Apps were methodically analyzed by the following items: Objective Features, List of Functionalities, Consistency in Outcomes and Usability. Results: Apps are presented in groups of features, as Dose Calculators (7 Apps, Clinical Calculators (4, Tools for Staging (7, Multipurpose (7 and Others (6. Each App is presented with the list of attributes and a brief comment. A short summary is provided at the end of each group. Discussion and Recommendations: There are numerous Apps with useful tools at the disposal of radiation oncologists. The most advisable Apps do not match the more expensive. Three all-in-one apps seem advisable above all: RadOnc Reference (in English, Easy Oncology (in German and iOncoR (in Spanish. Others recommendations are suggested for specific tasks: dose calculators, treatment-decision and staging.

  13. Building Web Apps for Google TV

    CERN Document Server

    Ferrate, Andres; Lee, Daniels; Ohye, Maile; Carff, Paul; Shen, Shawn; Hines, Steven

    2011-01-01

    By integrating the Web with traditional TV, Google TV offers developers an important new channel for content. But creating apps for Google TV requires learning some new skills-in fact, what you may already know about mobile or desktop web apps isn't entirely applicable. Building Web Apps for Google TV will help you make the transition to Google TV as you learn the tools and techniques necessary to build sophisticated web apps for this platform. This book shows you how Google TV works, how it fits into the web ecosystem, and what the opportunities are for delivering rich content to millions o

  14. Redefining Cheminformatics with Intuitive Collaborative Mobile Apps

    Science.gov (United States)

    Clark, Alex M; Ekins, Sean; Williams, Antony J

    2012-01-01

    Abstract The proliferation of mobile devices such as smartphones and tablet computers has recently been extended to include a growing ecosystem of increasingly sophisticated chemistry software packages, commonly known as apps. The capabilities that these apps can offer to the practicing chemist are approaching those of conventional desktop-based software, but apps tend to be focused on a relatively small range of tasks. To overcome this, chemistry apps must be able to seamlessly transfer data to other apps, and through the network to other devices, as well as to other platforms, such as desktops and servers, using documented file formats and protocols whenever possible. This article describes the development and state of the art with regard to chemistry-aware apps that make use of facile data interchange, and some of the scenarios in which these apps can be inserted into a chemical information workflow to increase productivity. A selection of contemporary apps is used to demonstrate their relevance to pharmaceutical research. Mobile apps represent a novel approach for delivery of cheminformatics tools to chemists and other scientists, and indications suggest that mobile devices represent a disruptive technology for drug discovery, as they have been to many other industries. PMID:23198002

  15. CSS for Windows 8 app development

    CERN Document Server

    Foster, Jeremy

    2013-01-01

    CSS for Windows 8 App Development is your learning guide for CSS - the language of great Windows 8-style apps. Learn the built-in styles that make the built-in controls shine, how to define them, and how to use CSS to give your custom app assets that beautiful Modern UI style. CSS (Cascading Style Sheets) is the clear standard for styling web applications, and with HTML, CSS, and JavaScript now powering apps on Windows 8, it's the clear standard there as well. CSS is a powerful styling and layout language that greatly simplifies the selection of page elements and their visual display, layout,

  16. UV Irradiation Accelerates Amyloid Precursor Protein (APP) Processing and Disrupts APP Axonal Transport

    Science.gov (United States)

    Almenar-Queralt, Angels; Falzone, Tomas L.; Shen, Zhouxin; Lillo, Concepcion; Killian, Rhiannon L.; Arreola, Angela S.; Niederst, Emily D.; Ng, Kheng S.; Kim, Sonia N.; Briggs, Steven P.; Williams, David S.

    2014-01-01

    Overexpression and/or abnormal cleavage of amyloid precursor protein (APP) are linked to Alzheimer's disease (AD) development and progression. However, the molecular mechanisms regulating cellular levels of APP or its processing, and the physiological and pathological consequences of altered processing are not well understood. Here, using mouse and human cells, we found that neuronal damage induced by UV irradiation leads to specific APP, APLP1, and APLP2 decline by accelerating their secretase-dependent processing. Pharmacological inhibition of endosomal/lysosomal activity partially protects UV-induced APP processing implying contribution of the endosomal and/or lysosomal compartments in this process. We found that a biological consequence of UV-induced γ-secretase processing of APP is impairment of APP axonal transport. To probe the functional consequences of impaired APP axonal transport, we isolated and analyzed presumptive APP-containing axonal transport vesicles from mouse cortical synaptosomes using electron microscopy, biochemical, and mass spectrometry analyses. We identified a population of morphologically heterogeneous organelles that contains APP, the secretase machinery, molecular motors, and previously proposed and new residents of APP vesicles. These possible cargoes are enriched in proteins whose dysfunction could contribute to neuronal malfunction and diseases of the nervous system including AD. Together, these results suggest that damage-induced APP processing might impair APP axonal transport, which could result in failure of synaptic maintenance and neuronal dysfunction. PMID:24573290

  17. A Guide to Help Consumers Choose Apps and Avoid App Overload

    Science.gov (United States)

    Schuster, Ellen; Zimmerman, Lynda

    2014-01-01

    Mobile technology has transformed the way consumers access and use information. The exponential growth of mobile apps makes finding suitable, easy-to-use nutrition and health-related apps challenging. A guide for consumers helps them ask important questions before downloading apps. The guide can be adapted for other Extension disciplines.

  18. Detecting android malicious apps and categorizing benign apps with ensemble of classifiers

    KAUST Repository

    Wang, Wei

    2017-01-17

    Android platform has dominated the markets of smart mobile devices in recent years. The number of Android applications (apps) has seen a massive surge. Unsurprisingly, Android platform has also become the primary target of attackers. The management of the explosively expansive app markets has thus become an important issue. On the one hand, it requires effectively detecting malicious applications (malapps) in order to keep the malapps out of the app market. On the other hand, it needs to automatically categorize a big number of benign apps so as to ease the management, such as correcting an app’s category falsely designated by the app developer. In this work, we propose a framework to effectively and efficiently manage a big app market in terms of detecting malapps and categorizing benign apps. We extract 11 types of static features from each app to characterize the behaviors of the app, and employ the ensemble of multiple classifiers, namely, Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Naive Bayes (NB), Classification and Regression Tree (CART) and Random Forest (RF), to detect malapps and to categorize benign apps. An alarm will be triggered if an app is identified as malicious. Otherwise, the benign app will be identified as a specific category. We evaluate the framework on a large app set consisting of 107,327 benign apps as well as 8,701 malapps. The experimental results show that our method achieves the accuracy of 99.39% in the detection of malapps and achieves the best accuracy of 82.93% in the categorization of benign apps.

  19. App Usage Factor: A Simple Metric to Compare the Population Impact of Mobile Medical Apps.

    Science.gov (United States)

    Lewis, Thomas Lorchan; Wyatt, Jeremy C

    2015-08-19

    One factor when assessing the quality of mobile apps is quantifying the impact of a given app on a population. There is currently no metric which can be used to compare the population impact of a mobile app across different health care disciplines. The objective of this study is to create a novel metric to characterize the impact of a mobile app on a population. We developed the simple novel metric, app usage factor (AUF), defined as the logarithm of the product of the number of active users of a mobile app with the median number of daily uses of the app. The behavior of this metric was modeled using simulated modeling in Python, a general-purpose programming language. Three simulations were conducted to explore the temporal and numerical stability of our metric and a simulated app ecosystem model using a simulated dataset of 20,000 apps. Simulations confirmed the metric was stable between predicted usage limits and remained stable at extremes of these limits. Analysis of a simulated dataset of 20,000 apps calculated an average value for the app usage factor of 4.90 (SD 0.78). A temporal simulation showed that the metric remained stable over time and suitable limits for its use were identified. A key component when assessing app risk and potential harm is understanding the potential population impact of each mobile app. Our metric has many potential uses for a wide range of stakeholders in the app ecosystem, including users, regulators, developers, and health care professionals. Furthermore, this metric forms part of the overall estimate of risk and potential for harm or benefit posed by a mobile medical app. We identify the merits and limitations of this metric, as well as potential avenues for future validation and research.

  20. ADDITIONAL STREET BERBASIS APP INVENTOR

    Directory of Open Access Journals (Sweden)

    Mohammad Adib Adhi Prabowo

    2013-05-01

    Full Text Available Abstrak Seiring dengan perkembangan sistem operasi android, telah banyak aplikasi yang memanfaatkan fasilitas GPS dan Google Map, seperti untuk mencari rute, mendapatkan peta, mencari lokasi tertentu pada sebuah tempat. Akan tetapi seringkali pengguna perangkat bergerak kesulitan ketika ingin mengetahui beberapa tempat dan lokasi tertentu karena belum ada fasilitas yang menyediakan informasi lokasi suatu tempat. Walaupun ada informasi lokasi pada peta biasanya informasi yang diberikan lokasi tempat berskala besar, misalnya lokasi tempat wisata atau stasiun kereta api. Pengembangan aplikasi untuk skala kecil ini akan memberikan informasi yang dipresentasikan pada google map. Selama ini belum ada yang memberikan sebuah informasi lokasi tempat penting yang berskala kecil. Misalnya informasi lokasi  tambal ban, lokasi warung makan, lokasi laundry, dan lokasi bengkel motor. Oleh karena itu kami mencoba untuk mengembangkan aplikasi additional street berbasis android via App Inventor dengan bantuan google maps. Aplikasi additional street ini dapat memberikan informasi letak objek pada peta serta memberikan informasi jalan menuju lokasi tersebut dan detail informasi lokasi tersebut serta lokasi dari pengguna aplikasi tersebut. Kata Kunci: additional street, android, google maps, app inventor, GPS

  1. Popular weight-management apps: Their use and quality

    Directory of Open Access Journals (Sweden)

    Juliana Chen

    2015-09-01

    Conclusions: While greater popularity of apps was associated with higher quality, the overall quality of commercial dietary weight-management apps remains suboptimal. Popular weight-management apps are useful for self-monitoring, however are lacking in the recognised behavioural change techniques that may facilitate changes in health behaviours. With the majority of these apps designed for self-directed management, strategies to improve the rigour of these apps are warranted and commercial app developers could benefit from collaboration with behavioural researchers.

  2. Apps of steel: are exercise apps providing consumers with realistic expectations?: a content analysis of exercise apps for presence of behavior change theory.

    Science.gov (United States)

    Cowan, Logan T; Van Wagenen, Sarah A; Brown, Brittany A; Hedin, Riley J; Seino-Stephan, Yukiko; Hall, P Cougar; West, Joshua H

    2013-04-01

    To quantify the presence of health behavior theory constructs in iPhone apps targeting physical activity. This study used a content analysis of 127 apps from Apple's (App Store) Health & Fitness category. Coders downloaded the apps and then used an established theory-based instrument to rate each app's inclusion of theoretical constructs from prominent behavior change theories. Five common items were used to measure 20 theoretical constructs, for a total of 100 items. A theory score was calculated for each app. Multiple regression analysis was used to identify factors associated with higher theory scores. Apps were generally observed to be lacking in theoretical content. Theory scores ranged from 1 to 28 on a 100-point scale. The health belief model was the most prevalent theory, accounting for 32% of all constructs. Regression analyses indicated that higher priced apps and apps that addressed a broader activity spectrum were associated with higher total theory scores. It is not unexpected that apps contained only minimal theoretical content, given that app developers come from a variety of backgrounds and many are not trained in the application of health behavior theory. The relationship between price and theory score corroborates research indicating that higher quality apps are more expensive. There is an opportunity for health and behavior change experts to partner with app developers to incorporate behavior change theories into the development of apps. These future collaborations between health behavior change experts and app developers could foster apps superior in both theory and programming possibly resulting in better health outcomes.

  3. App Development Paradigms for Instructional Developers

    Science.gov (United States)

    Luterbach, Kenneth J.; Hubbell, Kenneth R.

    2015-01-01

    To create instructional apps for desktop, laptop and mobile devices, developers must select a development tool. Tool selection is critical and complicated by the large number and variety of app development tools. One important criterion to consider is the type of development environment, which may primarily be visual or symbolic. Those distinct…

  4. Cool Apps: Productivity at Your Fingertips

    Science.gov (United States)

    Flaherty, Bill

    2013-01-01

    In addition to listing apps and their value, this article focuses on ways people can be more productive by adopting certain workflows in several ways. Apps listed herein include those useful in calendaring, printing, photo-editing, image-recognition, image scanning, electronic signatures, and making and sharing lists and notes.

  5. Will HTML5 Kill the Native App?

    Science.gov (United States)

    Fredette, Michelle

    2013-01-01

    For colleges and universities today, the question is no longer whether to develop a campus app or not. Instead, the debate has shifted to the best--and most cost-efficient--way to make campus applications accessible to the myriad devices and operating systems out there. Schools have a few options: They can develop multiple native app versions;…

  6. Smartphone-apps som nyt psykiatrisk behandlingstiltag

    DEFF Research Database (Denmark)

    Dalum, Anette Ellegaard; Arnfred, Sidse

    2014-01-01

    The number of smartphone apps for people with mental health issues is undergoing a dramatical growth in these years. We review the available literature on the topic, discuss opportunities and theoretical considerations using smartphone apps in psychiatric treatment and provide an overview...

  7. Gebruikersdata bij abonnementen in app stores

    NARCIS (Netherlands)

    Roosendaal, A.P.C.; Nieuwenhuis, O.A.

    2013-01-01

    Kranten en tijdschriften bieden tegenwoordig vaak, naast de papieren edities, digitale abonnementen aan. De content wordt in dat geval via een app gelezen op een mobiele device, zoals een smartphone of tablet. Om abonnementen in deze vorm aan te kunnen bieden is het bouwen van een app noodzakelijk.

  8. iPhone Apps for Smoking Cessation

    Science.gov (United States)

    Abroms, Lorien C.; Padmanabhan, Nalini; Thaweethai, Lalida; Phillips, Todd

    2012-01-01

    Background With the proliferation of smartphones such as the iPhone, mobile phones are being used in novel ways to promote smoking cessation. Purpose This study set out to examine the content of the 47 iPhone applications (apps) for smoking cessation that were distributed through the online iTunes store, as of June 24, 2009. Methods Each app was independently coded by two reviewers for their (1) approach to smoking cessation and their (2) adherence to the U.S. Public Health Service’s 2008 Clinical Practice Guidelines for Treating Tobacco Use and Dependence. Apps were also coded for their (3) frequency of downloads. Results Apps identified for smoking cessation were found to have low levels of adherence to key guidelines in the index. Few, if any, apps recommended or linked the user to proven treatments such as pharmacotherapy, counseling, and/or a quitline. Conclusions iPhone apps for smoking cessation rarely adhere to established guidelines for smoking cessation. It is recommended that current apps be revised and future apps be developed around evidence-based practices for smoking cessation. PMID:21335258

  9. Smartphone apps as a new psychiatric treatment

    DEFF Research Database (Denmark)

    Dalum, Anette Ellegaard; Arnfred, Sidse Marie

    2014-01-01

    Søg 1 - 1 ud af 1 Smartphone apps as a new psychiatric treatment. Anette Ellegaard Dalum, Sidse Arnfred, 2014, vol. 176, nummer 34, 2014. Ugeskrift for laeger Artikel Importer Fjern......Søg 1 - 1 ud af 1 Smartphone apps as a new psychiatric treatment. Anette Ellegaard Dalum, Sidse Arnfred, 2014, vol. 176, nummer 34, 2014. Ugeskrift for laeger Artikel Importer Fjern...

  10. Fra app'ernes planet til klasserummet

    DEFF Research Database (Denmark)

    Falkesgaard Slot, Marie; Gissel, Stig Toke; Lorentzen, Rasmus Fink

    2013-01-01

    Artiklen udpeger en række kategorier og begreber, som læreren kan anvende i sit arbejde med at analysere og vurdere hvilke handle- og betydningsmuligheder, der er indbygget i hhv. funktionelle, didaktiske og semantiske apps. Med afsæt i disse begreber gives praksisnære bud på, hvordan apps på for...

  11. The Electronic Discharge Letter Mobile App

    NARCIS (Netherlands)

    Lezcano, Leonardo; Ternier, Stefaan; Drachsler, Hendrik; Kalz, Marco; Specht, Marcus

    2013-01-01

    Lezcano, L., Ternier, S., Drachsler, H., Kalz, M., & Specht, M. (2013, September). The Electronic Discharge Letter Mobile App. In iProceedings of MEDICINE 2.0: 6th World Congress on Social Media, Mobile Apps, Internet/Web 2.0 (pp. 221-222). London, England. Retrieved from

  12. Social anxiety apps: a systematic review and assessment of app descriptors across mobile store platforms.

    Science.gov (United States)

    Alyami, Mohsen; Giri, Bachan; Alyami, Hussain; Sundram, Frederick

    2017-08-01

    The aim of this systematic review is twofold: (1) to characterise the purpose and description of available social anxiety apps and (2) to review the evidence on the effectiveness of social anxiety apps. A search was conducted on three major mobile platforms: Apple iTunes, Google Play and Windows Store. Apps were included if they addressed social anxiety and used an English language interface. A systematic review of the literature from MEDLINE, EMBASE, PsycINFO, Cochrane, Scopus and Web of Science to identify evidence-based evaluations of social anxiety apps was also undertaken. Of the 1154 apps identified, 38 apps met the inclusion criteria: iTunes (n=18), Google Play (n=16) and Windows Store (n=4). Over 60% of apps were exclusively focused on social anxiety, while the remainder targeted social anxiety and related conditions. Most developers did not provide information on their organisational affiliations or their content source. Most apps used multimedia while 17 apps used text only. Finally, although the systematic review of the literature identified 94 articles, none of which met inclusion criteria. Social anxiety apps have the potential to overcome barriers to accessing treatment; however, none of the apps identified have had studies on their effectiveness published. As the evidence base is lacking, it is therefore not currently possible to recommend their use. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. La generación app (The App Generation

    Directory of Open Access Journals (Sweden)

    Luque, Mónica

    2014-12-01

    Full Text Available La reciente publicación de Gardner, en colaboración con Katie Davis, propone una interesante línea de indagación y reflexión en torno a las jóvenes generaciones. En primer término, lo particular de este grupo etario consiste en que son los únicos que no han conocido un mundo sin la ubicuidad que ofrecen los medio digitales. Por tanto, Gardner indica que las apps están modificando el desarrollo psicológico de los jóvenes, quienes tienden actualmente a ser más renuentes al riesgo que las generaciones anteriores. En segundo lugar, pareciera que dicho riesgo afecta el comportamiento social.

  14. Cell biology apps for Apple devices.

    Science.gov (United States)

    Stark, Louisa A

    2012-01-01

    Apps for touch-pad devices hold promise for guiding and supporting learning. Students may use them in the classroom or on their own for didactic instruction, just-in-time learning, or review. Since Apple touch-pad devices (i.e., iPad and iPhone) have a substantial share of the touch-pad device market (Campbell, 2012), this Feature will explore cell biology apps available from the App Store. My review includes iPad and iPhone apps available in June 2012, but does not include courses, lectures, podcasts, audiobooks, texts, or other books. I rated each app on a five-point scale (1 star = lowest; 5 stars = highest) for educational and production values; I also provide an overall score.

  15. Forensic Taxonomy of Android Social Apps.

    Science.gov (United States)

    Azfar, Abdullah; Choo, Kim-Kwang Raymond; Liu, Lin

    2017-03-01

    An Android social app taxonomy incorporating artifacts that are of forensic interest will enable users and forensic investigators to identify the personally identifiable information (PII) stored by the apps. In this study, 30 popular Android social apps were examined. Artifacts of forensic interest (e.g., contacts lists, chronology of messages, and timestamp of an added contact) were recovered. In addition, images were located, and Facebook token strings used to tie account identities and gain access to information entered into Facebook by a user were identified. Based on the findings, a two-dimensional taxonomy of the forensic artifacts of the social apps is proposed. A comparative summary of existing forensic taxonomies of different categories of Android apps, designed to facilitate timely collection and analysis of evidentiary materials from Android devices, is presented. © 2016 American Academy of Forensic Sciences.

  16. Smart apps for the smart plastic surgeon

    Directory of Open Access Journals (Sweden)

    Aniketh Venkataram

    2015-01-01

    Full Text Available Smartphones have the ability to benefit plastic surgeons in all aspects of patient care and education. With the sheer number of applications available and more being created everyday, it is easy to miss out on apps which could be of great relevance. Moreover, the range of android applications available has not been extensively discussed in the literature. To this end, we have compiled an exhaustive list of android smartphone applications, which we feel can help our day to day functioning. The apps have been extensively reviewed and neatly described along with all their potential uses. In addition, we have made an effort to highlight ′non-medical′ or efficiency apps which can improve departmental functioning. These apps have not been described in prior articles, and their functionality might not be known to all. We believe that the technology savvy plastic surgeon can make maximum use of these apps to his benefit.

  17. Review of Cadw Mobile App [application

    Directory of Open Access Journals (Sweden)

    Miriam Rothenberg

    2017-06-01

    Full Text Available The Welsh Government's historic environment service, Cadw (Welsh: 'to keep, protect', released a mobile app in early 2016 so that members of the public can learn about and plan visits to heritage sites cared for by Cadw. With more than one hundred archaeological sites available for browsing, conveniently ordered by spatial proximity to the user, and with a clean and accessible user-interface, the app effectively showcases the richness and distinctive character of Wales's archaeological record. The app is free and available to download for both iOS and Android devices (from Apple's App Store and the Google Play Store, and is also well signposted on Cadw's website. This article is a review of the Cadw mobile app.

  18. Cadmium exposure in the Swedish environment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This report gives a thorough description of cadmium in the Swedish environment. It comprises three parts: Cadmium in Sweden - environmental risks;, Cadmium in goods - contribution to environmental exposure;, and Cadmium in fertilizers, soil, crops and foods - the Swedish situation. Separate abstracts have been prepared for all three parts

  19. Endoparasites in some Swedish Amphibians

    DEFF Research Database (Denmark)

    Cedhagen, Tomas

    1988-01-01

    A study was made of the endoparasites in specimens of Rana arvalis and R. temporaria collected on two occasions from a locality of southern Sweden. Some frogs were investigated directly after capture while other frogs were kept hibernating and the composition of the parasites as well...... as the behaviour of the parasites were studied after the termination of hibernation. Twelve species of parasites were found. Six of them, Polystoma integerrimum, Pleurogenes claviger (Trematoda), Rhabdias bufonis, Oswaldocruzia filiformis, Cosmocerca ornata and Oxysomatium brevicauda- tum (Nematoda), have...... not previously been reported from Sweden. The late Prof. O. Nybelin's unpublished records of parasites found in Swedish amphibians are also given....

  20. App Chronic Disease Checklist: Protocol to Evaluate Mobile Apps for Chronic Disease Self-Management

    Science.gov (United States)

    Anderson, Kevin; Burford, Oksana

    2016-01-01

    Background The availability of mobile health apps for self-care continues to increase. While little evidence of their clinical impact has been published, there is general agreement among health authorities and authors that consumers’ use of health apps assist in self-management and potentially clinical decision making. A consumer’s sustained engagement with a health app is dependent on the usability and functionality of the app. While numerous studies have attempted to evaluate health apps, there is a paucity of published methods that adequately recognize client experiences in the academic evaluation of apps for chronic conditions. Objective This paper reports (1) a protocol to shortlist health apps for academic evaluation, (2) synthesis of a checklist to screen health apps for quality and reliability, and (3) a proposed method to theoretically evaluate usability of health apps, with a view towards identifying one or more apps suitable for clinical assessment. Methods A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram was developed to guide the selection of the apps to be assessed. The screening checklist was thematically synthesized with reference to recurring constructs in published checklists and related materials for the assessment of health apps. The checklist was evaluated by the authors for face and construct validity. The proposed method for evaluation of health apps required the design of procedures for raters of apps, dummy data entry to test the apps, and analysis of raters’ scores. Results The PRISMA flow diagram comprises 5 steps: filtering of duplicate apps; eliminating non-English apps; removing apps requiring purchase, filtering apps not updated within the past year; and separation of apps into their core functionality. The screening checklist to evaluate the selected apps was named the App Chronic Disease Checklist, and comprises 4 sections with 6 questions in each section. The validity check verified

  1. Mobile app rating scale: a new tool for assessing the quality of health mobile apps.

    Science.gov (United States)

    Stoyanov, Stoyan R; Hides, Leanne; Kavanagh, David J; Zelenko, Oksana; Tjondronegoro, Dian; Mani, Madhavan

    2015-03-11

    The use of mobile apps for health and well being promotion has grown exponentially in recent years. Yet, there is currently no app-quality assessment tool beyond "star"-ratings. The objective of this study was to develop a reliable, multidimensional measure for trialling, classifying, and rating the quality of mobile health apps. A literature search was conducted to identify articles containing explicit Web or app quality rating criteria published between January 2000 and January 2013. Existing criteria for the assessment of app quality were categorized by an expert panel to develop the new Mobile App Rating Scale (MARS) subscales, items, descriptors, and anchors. There were sixty well being apps that were randomly selected using an iTunes search for MARS rating. There were ten that were used to pilot the rating procedure, and the remaining 50 provided data on interrater reliability. There were 372 explicit criteria for assessing Web or app quality that were extracted from 25 published papers, conference proceedings, and Internet resources. There were five broad categories of criteria that were identified including four objective quality scales: engagement, functionality, aesthetics, and information quality; and one subjective quality scale; which were refined into the 23-item MARS. The MARS demonstrated excellent internal consistency (alpha = .90) and interrater reliability intraclass correlation coefficient (ICC = .79). The MARS is a simple, objective, and reliable tool for classifying and assessing the quality of mobile health apps. It can also be used to provide a checklist for the design and development of new high quality health apps.

  2. Creating mobile apps with Appcelerator Titanium

    CERN Document Server

    Brousseau, Christian

    2013-01-01

    Creating Mobile Apps with Appcelerator Titanium provides a hands-on approach and working examples on creating apps and games as well as embedding them onto a social networking website. Developers can then move on from there to develop their own applications based on the ones they have developed throughout the course of this book.""Creating Mobile Apps with Appcelerator Titanium"" is for developers who have experience with modern languages and development environments. Also, if you are familiar with the concepts of Object-oriented Programming (OOP), reusable components, AJAX closures, and so on

  3. Fra app'ernes planet til klasserummet

    DEFF Research Database (Denmark)

    Slot, Marie Falkesgaard; Bundsgaard, Jeppe; Gissel, Stig Toke

    2013-01-01

    Artiklen henvender sig til lærere og konsulenter, som ønsker at kvalificere deres fagsprog i arbejdet med apps og undervisningsdesign. Med udgangspunkt i læremiddeldidaktikken udpeger vi en række kategorier og begreber, som læreren kan anvende i sit arbejde med at analysere og vurdere hvilke handle......- og betydningsmuligheder, der er indbygget i hhv. funktionelle, didaktiske og semantiske apps. Med afsæt i disse begreber giver vi praksisnære bud på, hvordan apps på forskellig vis kan indbygges i fagundervisningen....

  4. Pro JavaScript for web apps

    CERN Document Server

    Freeman, Adam

    2012-01-01

    JavaScript is the engine behind every web app, and a solid knowledge of it is essential for all modern web developers. Pro JavaScript for Web Apps gives you all of the information that you need to create professional, optimized, and efficient JavaScript applications that will run across all devices. It takes you through all aspects of modern JavaScript application creation, showing you how to combine JavaScript with the new features of HTML5 and CSS3 to make the most of the new web technologies. The focus of the book is on creating professional web applications, ensuring that your app provides

  5. Beyond Native Apps: Web Technologies to the Rescue! (Keynote)

    NARCIS (Netherlands)

    Malavolta, Ivano

    2016-01-01

    As of today, mobile software development teams can follow a number of different development and distribution strategies, ranging from native apps, to mobile web apps, hybrid apps, and the recently emerging progressive web apps. This talk provides a state-of-the-art overview of the development

  6. Direct to Consumer Mobile Teledermatology Apps: An Exploratory Study

    OpenAIRE

    Kochmann, Matthias; Locatis, Craig

    2016-01-01

    Background: Since 2012, “Direct to Consumer” mobile teledermatology apps have become more available, relinquishing many data collection tasks normally done by healthcare professionals directly to patients. Introduction: To determine user friendliness, diagnostic quality, and service of commercially available mobile teledermatology apps. Materials and Methods: All mobile teledermatology apps available at the Apple App Store were reviewed. The two most popular mobile teledermatol...

  7. Exploring how to engage Swedish Millennials with pension planning

    OpenAIRE

    LÖVGREN, ANDREAS; MAGNUSSON, MATTIAS

    2016-01-01

    An aging Swedish population is putting an increased pressure on the Swedish pension system. To address this, the Swedish pension system was reformed in the late 1990s. This reformation resulted in an increased individual responsibility for pension investments among the Swedish population. The individual responsibility has shown to be challenging for many since they feel a great uncertainty in this area. Adding to the notion that the Swedish population is aging; young Swedes are also entering ...

  8. Productive mutants of niger

    International Nuclear Information System (INIS)

    Misra, R.C.

    2001-01-01

    Seeds of six niger (Guizotia abyssinica Cass.) varieties ('GA-10', 'ONS-8', 'IGP-72', 'N-71', 'NB-9' and 'UN-4') were treated with 0.5, 0.75 and 1% ethyl methanesulphonate. After four generations of selection, 29 mutant lines were developed and those were evaluated from 1990-92 during Kharif (July to October) and Rabi (December to March) seasons. Average plant characteristics and yield data of four high yielding mutants along with 'IGP-76' (National Check), GA-10 (Zonal Check) and 'Semiliguda Local' (Local Check) are presented

  9. Anxiety: There is an app for that. A systematic review of anxiety apps.

    Science.gov (United States)

    Sucala, Madalina; Cuijpers, Pim; Muench, Frederick; Cardoș, Roxana; Soflau, Radu; Dobrean, Anca; Achimas-Cadariu, Patriciu; David, Daniel

    2017-06-01

    Smartphones and mobile devices have become ubiquitous, and with the rapid advance of technology, the number of health applications (apps) that are available for consumers on these devices is constantly growing. In particular, there has been a recent proliferation of anxiety apps. However, there has been no review of the quality or content of these anxiety apps and little is known about their purpose, the features they contain, and their empirical support. The goal of this systematic review was to assess the commercially available anxiety apps. A list of anxiety apps was collected in January 2017, using the Power Search function of iTunes and Google Play. Of 5,078 identified apps, 52 met our inclusion criteria (i.e., being defined as an anxiety/worry relief app, and offering psychological techniques aimed primarily at reducing anxiety) and were further reviewed. The majority (67.3%) of the currently available anxiety apps were found to lack the involvement of health care professionals in their development, and very few (3.8%) of them have been rigorously tested. At the moment, although anxiety apps have the potential to enhance access to mental health care, there is a marked discrepancy between the wealth of commercially available apps, and the paucity of data regarding their efficacy and effectiveness. Although the great promise of apps is their ability to increasing access to evidence-based mental health, the field is not quite there yet and the full potential of apps for treating anxiety has yet to be exploited. © 2017 Wiley Periodicals, Inc.

  10. Predominant discourses in Swedish nursing.

    Science.gov (United States)

    Dahlborg-Lyckhage, Elisabeth; Pilhammar-Anderson, Ewa

    2009-05-01

    The aim of this study was to elucidate the predominant discourse in the field of Swedish nursing in 2000, 25 years after nursing was introduced as an academic discipline in Sweden. The method used was content analysis and deconstructive analysis of discourses. Laws, statutes, regulations, and examination requirements, including official reports, recruitment campaigns, and media coverage, were analyzed. The findings uncovered competing discourses striving to gain hegemony. In the public sector, official requirements competed against the media fixation on gender stereotypes and the realities of local recruitment campaigns. Media has a major role in disseminating prevailing conceptions and conventions pertaining to the nursing profession. As a result, decision makers, students, patients, and family members could get lower expectations of the professional competence of nursing practitioners than would otherwise have been the case in the absence of media exposure.

  11. Studies in Swedish Energy Opinion

    Energy Technology Data Exchange (ETDEWEB)

    Holmberg, Soeren; Hedberg, Per

    2012-07-01

    the 1970s, energy production was politicized big time in the industrialized world. The birth of the environmental movement, the oil crises in 1973 - 74 and the beginning conflict surrounding civilian nuclear power, put energy issues center stage on the political agenda. Energy policies - especially related to the development of nuclear power - came to dominate election campaigns, like in Sweden in 1976 or be the subject of referendums, like in Austria in 1978 or in Sweden in 1980. Critical voices toward the peaceful use of nuclear power - having started in America before being exported to Europe - gained real strength and public support all over the Western world by the nuclear accident at the Three Mile Island plant in Harrisburg, Pennsylvania in 1979. The energy genie was out of the bottle and out to stay. Fueled by the nuclear meltdowns in Chernobyl in 1986 and in Fukushima in 2011 and supplemented by conflicts over how to reduce the use of oil and coal, how to sensibly exploit the waste gas reserves, and how to develop renewable energy sources based on sun, wind and waves – have made all kinds of energy issues the focal point of political contentions ever since the early 1970s. In Sweden, as in many other countries, energy policies - often with nuclear power in the center - have been one of the most fought-over policy areas during the last thirty-forty years. And the contentious character of energy policies is not limited to the elite level of politics - to politicians, to media pundits or to lobbyists. It is also manifest among ordinary citizens. Energy issues - nuclear power and wind power in particular - are highly polarizing among voters as well. Given this historic background, starting in the 1970s, it was rather natural that energy questions - featuring most prominently questions related to nuclear power - would be important parts of the voter surveys performed by the Swedish National Elections Studies (SNES) at the Univ. of Gothenburg. The first book

  12. Development of an app for compressible flow “App4Comp”

    OpenAIRE

    Adam Alberdi, Andrés; Gámez Montero, Pedro Javier

    2015-01-01

    In this paper is discussed the development and operation of a new Android App made through Google’s platform App Inventor 2. This App is focused on solving classic problems related to compressible flow, dealing with the typical cases seen in the subject of Fluid Mechanics of a degree in Aeronautics. It is downloadable from [1], or through the QR code at the end of this paper. The main objective of this project was to bring in a new, useful app about compressible flow to the market, but als...

  13. From analogue to apps--developing an app to prepare children for medical imaging procedures.

    Science.gov (United States)

    Williams, Gigi; Greene, Siobhan

    2015-01-01

    The Royal Children's Hospital (RCH) in Melbourne has launched a world-first app for children that will help reduce anxiety and the need for anesthesia during medical imaging procedures. The free, game-based app, "Okee in Medical Imaging", helps children aged from four to eight years to prepare for all medical imaging procedures--X-ray, CT, MRI, ultrasound, nuclear medicine, and fluoroscopy. The app is designed to reduce anticipatory fear of imaging procedures, while helping to ensure that children attend imaging appointments equipped with the skills required for efficient and effective scans to be performed. This paper describes how the app was developed.

  14. iPad apps for orthopedic surgeons.

    Science.gov (United States)

    Franko, Orrin I; Bhola, Siddharth

    2011-12-01

    The development and distribution of mobile applications, or apps, designed for medical professionals and patients is quickly expanding, and within this group are apps designed specifically for orthopedic use. Currently, the most popular mobile apps are sponsored by private companies and focus on delivering device-specific information. If this trend toward the use of privately funded educational materials continues, regulations may need to be established to ensure that the information provided is accurate, honest, and supported by peer-reviewed literature. It will likely be the responsibility of the orthopedic community to ensure that the development and use of these apps has appropriate oversight and validation as they are incorporated into clinical practice and training. Copyright © 2011, SLACK Incorporated.

  15. iOS app development for dummies

    CERN Document Server

    Feiler, Jesse

    2014-01-01

    If you've got incredible iOS ideas, get this book and bring them to life! iOS 7 represents the most significant update to Apple's mobile operating system since the first iPhone was released, and even the most seasoned app developers are looking for information on how to take advantage of the latest iOS 7 features in their app designs. That's where iOS App Development For Dummies comes in! Whether you're a programming hobbyist wanting to build an app for fun or a professional developer looking to expand into the iOS market, this book will walk you through the fundamentals of building a univer

  16. 15 CFR 740.7 - Computers (APP).

    Science.gov (United States)

    2010-01-01

    ... software described in paragraph (a)(2) of this section for computers of unlimited APP are eligible for...) Review by other departments or agencies. The Departments of Defense, State, Energy, and other agencies...

  17. Biomass and Swedish energy policy

    International Nuclear Information System (INIS)

    Johansson, Bengt

    2001-01-01

    The use of biomass in Sweden has increased by 44% between 1990 and 1999. In 1999 it was 85 TWh, equivalent to 14% of the total Swedish energy supply. The existence of large forest industry and district heating systems has been an essential condition for this expansion. The tax reform in 1991 seems, however, to have been the most important factor responsible for the rapid bioenergy expansion. Through this reform, the taxation of fossil fuels in district heating systems increased by approximately 30-160%, depending on fuel, whereas bioenergy remained untaxed. Industry is exempted from the energy tax and pays reduced carbon tax. No tax is levied on fossil fuels used for electricity production. Investment grants have existed for biomass-based electricity production but these grants have not been large enough to make biomass-based electricity production economically competitive in a period of falling electricity prices. Despite this, the biomass-based electricity production has increased slightly between 1990 and 1999. A new taxation system aiming at a removal of the tax difference between the industry, district heating and electricity sectors has recently been analysed by the Swedish government. One risk with such a system is that it reduces the competitiveness for biomass in district heating systems as it seems unlikely that the taxes on fossil fuels in the industry and electricity sectors will increase to a level much higher than in other countries. A new system, based on green certificates, for supporting electricity from renewable energy sources has also been proposed by the government.

  18. ''Are Chemistry Educational Apps Useful?''--A Quantitative Study with Three In-House Apps

    Science.gov (United States)

    Ping, Grace Lee Yuan; Lok, Chang; Yeat, Tan Wei; Cherynn, Tan Jie Ying; Tan, Emelyn Sue Qing

    2018-01-01

    Three internally developed mobile apps, "3D Sym Op", "SM2 Chem" and "ARMolVis," available for free on both the Apple App Store and Google Play Store were evaluated in seven studies. Each study was a systematic process of Pre-Test, In-lecture App Demo, App Assisted Interactive Tutorials (AAITs) and/or Independent App…

  19. Developing multiplatform apps : using hybrid solutions

    OpenAIRE

    Kristbergsson, Ellert

    2015-01-01

    The aim of this thesis is to describe the process of developing multiplatform apps for mobile phones by discussing and comparing the different methods of developing apps for all platforms. The purpose is to ease decision making of smaller companies that are starting to develop their own product for smartphones. The paper analyses tools based on the Cordova framework and the Qt framework. The difference between how the frameworks deliver the code to the machine, Cordova compiles JavaScript...

  20. MOTHER APP : a family memories theater

    OpenAIRE

    高, 磊; 奥出, 直人

    2011-01-01

    This thesis proposes MOTHER APP, an Application to Media Furniture Platform that creates a Family Memories Theater to document and exhibit shared household life experiences in the living room, automatically capturing spontaneous moments into photos by sensing if the family members are together through furniture. The thesis introduces the research, design process and implementation of MOTHER APP, describe the evalutation about how households use it to gain the new experience in the living room...

  1. Analysing customer behaviour in mobile app usage

    OpenAIRE

    Chen, Qianling; Zhang, Min; Zhao, Xiande

    2017-01-01

    Purpose – Big data produced by mobile apps contains valuable knowledge about customers and markets and has been viewed as productive resources. This study proposes a multiple methods approach to elicit intelligence and value from big data by analysing customer behaviour in mobile app usage. Design/methodology/approach – The big data analytical approach is developed using three data mining techniques: RFM (Recency, Frequency, Monetary) analysis, link analysis, and association rule learning. We...

  2. Enhancing Pharmacy Student Learning and Perceptions of Medical Apps

    OpenAIRE

    Rodis, Jennifer; Aungst, Timothy Dy; Brown, Nicole V; Cui, Yan; Tam, Leonard

    2016-01-01

    Background The use of mobile apps in health care is growing. Current and future practitioners must be equipped with the skills to navigate and utilize apps in patient care, yet few strategies exist for training health care professional students on the usage of apps. Objective To characterize first-year pharmacy student use of medical apps, evaluate first-year pharmacy student's perception of skills in finding, evaluating, and using medical apps before and after a focused learning experience, ...

  3. Apps for Hearing Science and Care.

    Science.gov (United States)

    Paglialonga, Alessia; Tognola, Gabriella; Pinciroli, Francesco

    2015-09-01

    Our research aims at the identification and assessment of applications (referred to as apps) in the hearing health care domain. This research forum article presents an overview of the current availability, affordability, and variety of hearing-related apps. The available apps were reviewed by searching on the leading platforms (iOS, Android, Windows Phone stores) using the keywords hearing, audiology, audio, auditory, speech, language, tinnitus, hearing loss, hearing aid, hearing sys tem, cochlear implant, implantable device, auditory training, hearing rehabilitation, and assistive technology/tool/device. O n the bas is of the offered services, apps were classified into 4 application domains: (a) screening and assessment, (b) intervention and rehabilitation, (c) education and information, and (d) assistive tools. A large variety of apps are available in the hearing health care domain. These cover a wide range of services for people with hearing or communication problems as well as for hearing professionals, families, or informal caregivers. This evolution can potentially bring along considerable advantages and improved outcomes in the field of hearing health care. Nevertheless, potential risks and threats (e.g., safety, quality, effectiveness, privacy, and regulation) should not be overlooked. Significant research—particularly in terms of assessment and guidance—is still needed for the informed, aware, and safe adoption of hearing-related apps by patients and professionals.

  4. Airport Surface Access and Mobile Apps

    Directory of Open Access Journals (Sweden)

    Luis Martin-Domingo

    2015-02-01

    Full Text Available Purpose: Airport Surface Access faces two main opposite issues: (1 cars, being the main transport mode, contribute to the increasing level of congestion and pollution of cities; and (2 simultaneously, parking fees are one important source of airports commercial revenue, creating a dilemma for airports when facing the problem. Following the recent trend of air passengers travelling with Smartphone (78% in 2013, the purpose of this paper is to monitor the adoption of mobile Applications (Apps by airports and to analyze if the information and functions provided in those Apps can help to overcome the above two issues. Design/methodology/approach: 31 iPhone App of some of the largest European airports were evaluated in the lab using the evaluation model of Destinations Mobile Applications (Scolari and Fernández-Cavia 2014 adapted for for the Airport Surface Access on Airport Apps Findings and Originality/value: The Apps evaluated provided a very limited functionality to help passengers to plan and book their trips to/from the airports on public transports and gave high priority to parking information and services. Originality/value: Although Airport Surface Access has been a widely researched, the originality of this paper is the analysis of airport mobile Apps as a potential tool for airports to deal with the surface airport access problems.Access, Airports, Mobile Internet, Commercial Revenues

  5. Assessing the usability of Shazam mobile app

    Science.gov (United States)

    Hussain, Azham; Mkpojiogu, Emmanuel O. C.; Almazini, Hassan; Almazini, Hussein

    2017-10-01

    Like searching for a "needle" in a "haystack", suppose that there is a large set of signals (finite sequences of numbers) fs1; s2; s3; g, and a special signal q that may or may not be in the collection. How can the signals be found in the collection that is similar, or identical to q, and how can this be done quickly? A solution to this question is the basis of the Shazam smart phone app, where a listener captures a short excerpt of a recorded song with the smart phone's microphone, and in a matter of moments the app reports the name of the song and the artist. Here, the "needle" is the excerpt, and the "haystack" is a vast corpus of popular music. The Shazam algorithm is powered by Fourier analysis. This paper presents a report on a usability evaluation of Amazon Shazam app. The researchers present the outcome based on a task-based evaluation that involved 15 users of different level of experience who performed 5 tasks using the Shazam mobile app. Post-test questionnaire was used to capture users' perceptions about the app. The results demonstrate that most of the participants were satisfied with services provided by the app.

  6. Suicide rate among former Swedish peacekeeping personnel.

    Science.gov (United States)

    Michel, Per-Olof; Lundin, Tom; Larsson, Gerry

    2007-03-01

    Increased suicide rates for military personnel suffering from post-traumatic stress disorders have been reported in various countries. Although it is known that some peacekeepers are exposed to potentially traumatic events and are thus at risk of suffering from post-traumatic stress reactions, only a few studies have examined suicide rates in this group. Therefore, the aim of this study was to investigate the suicide rate among former Swedish peacekeeping personnel. We compared 39,768 former Swedish peacekeepers to the general population in the National General Population Registry and the Cause-of-Death Registry. A lower number of suicides was found among former Swedish peacekeepers than in the general population. In conclusion, Swedish personnel serving in international peace-keeping operations do not show a higher suicide rate than the general population. Unique problems associated with this research area are discussed.

  7. Smartphone apps for orthopaedic sports medicine - a smart move?

    Science.gov (United States)

    Wong, Seng Juong; Robertson, Greg A; Connor, Katie L; Brady, Richard R; Wood, Alexander M

    2015-01-01

    With the advent of smartphones together with their downloadable applications (apps), there is increasing opportunities for doctors, including orthopaedic sports surgeons, to integrate such technology into clinical practice. However, the clinical reliability of these medical apps remains questionable. We reviewed available apps themed specifically towards Orthopaedic Sports Medicine and related conditions and assessed the level of medical professional involvement in their design and content, along with a review of these apps. The most popular smartphone app stores (Android, Apple, Blackberry, Windows, Samsung, Nokia) were searched for Orthopaedic Sports medicine themed apps, using the search terms; Orthopaedic Sports Medicine, Orthopaedics, Sports medicine, Knee Injury, Shoulder Injury, Anterior Cruciate Ligament Tear, Medial Collateral Ligament Tear, Rotator Cuff Tear, Meniscal Tear, Tennis Elbow. All English language apps related to orthopaedic sports medicine were included. A total of 76 individual Orthopaedic Sports Medicine themed apps were identified. According to app store classifications, there were 45 (59 %) medical themed apps, 28 (37 %) health and fitness themed apps, 1 (1 %) business app, 1 (1 %) reference app and 1 (1 %) sports app. Forty-nine (64 %) apps were available for download free of charge. For those that charged access, the prices ranged from £0.69 to £69.99. Only 51 % of sports medicine apps had customer satisfaction ratings and 39 % had named medical professional involvement in their development or content. We found the majority of Orthopaedic Sports Medicine apps had no named medical professional involvement, raising concerns over their content and evidence-base. We recommend increased regulation of such apps to improve the accountability of app content.

  8. Apps as Artefacts: Towards a Critical Perspective on Mobile Health and Medical Apps

    Directory of Open Access Journals (Sweden)

    Deborah Lupton

    2014-10-01

    Full Text Available Although over 100,000 health and medical mobile apps have been placed on the market, few critical social analyses have been yet undertaken of the role of these apps in healthcare, preventive health and health promotion. In this article I present an argument for approaching the study of mobile apps as sociocultural artefacts, focusing specifically on those that have been developed on health and medical topics. This perspective acknowledges that apps are digital objects that are the products of human decision-making, underpinned by tacit assumptions, norms and discourses already circulating in the social and cultural contexts in which they are generated, marketed and used. First, I provide the context, by discussing the gradual digitisation of health and medical information since the advent of the Internet and the emergence of health and medical apps as one of the latest developments. Second, I discuss how a critical perspective may be employed to analyse the social, cultural and political dimensions of health and medical apps. Finally I illustrate how such an approach may be applied by giving a case study of an analysis of the top 10 ranked health and medical apps on the Apple App Store on one day, outlining some major themes and discourses that emerge.

  9. Planet App: Kids' Book Apps Are Everywhere. But Are They Any Good?

    Science.gov (United States)

    Bird, Elizabeth

    2011-01-01

    A proper picture book app lets a parent and child read, listen to, or explore a book in a fun and interactive manner. Typical options offered in these apps include turning off the sound (so that a parent or child can read on their own), changing from one language to another, and small interactive features, such as making the characters move. To…

  10. How Do Apps Work? An Analysis of Physical Activity App Users' Perceptions of Behavior Change Mechanisms.

    Science.gov (United States)

    Hoj, Taylor H; Covey, Emarie L; Jones, Allyn C; Haines, Amanda C; Hall, P Cougar; Crookston, Benjamin T; West, Joshua H

    2017-08-03

    Physical activity apps are commonly used to increase levels of activity and health status. To date, the focus of research has been to determine the potential of apps to influence behavior, to ascertain the efficacy of a limited number of apps to change behavior, and to identify the characteristics of apps that users prefer. The purpose of this study was to identify the mechanisms by which the use of physical activity apps may influence the users' physical activity behavior. This study used a cross-sectional survey of users of health-related physical activity apps during the past 6 months. An electronic survey was created in Qualtrics' Web-based survey software and deployed on Amazon Mechanical Turk. Individuals who had used at least one physical activity app in the past 6 months were eligible to respond. The final sample comprised 207 adults living in the United States. 86.0% (178/207) of respondents were between the ages of 26 and 54 years, with 51.2% (106/207) of respondents being female. Behavior change theory informed the creation of 20 survey items relating to the mechanisms of behavior change. Respondents also reported about engagement with the apps, app likeability, and physical activity behavior. Respondents reported that using a physical activity app in the past 6 months resulted in a change in their attitudes, beliefs, perceptions, and motivation. Engagement with the app (Pmechanisms of change. The mechanisms of change were associated with self-reported physical activity behaviors (Pmechanisms by which apps may impact behavior. App developers may wish to incorporate these mechanisms in an effort to increase impact. Practitioners should consider the extent to which behavior change theory is integrated into a particular app when they consider making recommendations to others wishing to increase levels of physical activity. ©Taylor H Hoj, Emarie L Covey, Allyn C Jones, Amanda C Haines, P Cougar Hall, Benjamin T Crookston, Joshua H West. Originally published

  11. Mobile medical apps for patient education: a graded review of available dermatology apps.

    Science.gov (United States)

    Masud, Aisha; Shafi, Shahram; Rao, Babar K

    2018-02-01

    The utilization of mobile applications (apps) as educational resources for patients highlights the need for an objective method of evaluating the quality of health care-related mobile apps. In this study, a quantified rubric was developed to objectively grade publicly available dermatology mobile apps with the primary focus of patient education. The rubric included 5 criteria thought to be most important in evaluating the adequacy of these apps in relaying health information to patients: educational objectives, content, accuracy, design, and conflict of interest. A 4-point scale was applied to each criterion. The use of this objective rubric could have implications in the evaluation and recommendation of mobile health care apps as a vital educational resource for patients.

  12. Commercially available mobile phone headache diary apps: a systematic review.

    Science.gov (United States)

    Hundert, Amos S; Huguet, Anna; McGrath, Patrick J; Stinson, Jennifer N; Wheaton, Mike

    2014-08-19

    Headache diaries are often used by headache sufferers to self-monitor headaches. With advances in mobile technology, mobile electronic diary apps are becoming increasingly common. This review aims to identify and evaluate all commercially available mobile headache diary apps for the two most popular mobile phone platforms, iOS and Android. The authors developed a priori a set of 7 criteria that define an ideal headache diary app intended to help headache sufferers better understand and manage their headaches, while providing relevant data to health professionals. The app criteria were intended as minimum requirements for an acceptable headache diary app that could be prescribed by health care professionals. Each app was evaluated and scored against each criterion. Of the 38 apps identified, none of the apps met all 7 app criteria. The 3 highest scoring apps, meeting 5 of the app criteria, were iHeadache (developed by Better QOL), ecoHeadache (developed by ecoTouchMedia), and Headache Diary Pro (developed by Froggyware). Only 18% of the apps were created with scientific or clinical headache expertise and none of the apps reported on psychometric properties. Despite the growing market and demand, there is a concerning lack of scientific expertise and evidence base associated with headache diary apps.

  13. Sleep apps and behavioral constructs: A content analysis.

    Science.gov (United States)

    Grigsby-Toussaint, Diana S; Shin, Jong Cheol; Reeves, Dayanna M; Beattie, Ariana; Auguste, Evan; Jean-Louis, Girardin

    2017-06-01

    Although sleep apps are among the most popular commercially available health apps, little is known about how well these apps are grounded in behavioral theory. Three-hundred and sixty-nine apps were initially identified using the term "sleep" from the Google play store and Apple iTunes in September 2015. The final sample consisted of 35 apps that met the following inclusion criteria: 1) Stand-alone functionality; 2) Sleep tracker or monitor apps ranked by 100 + users; 3) Sleep Alarm apps ranked by 1000 + users; and 4) English language. A coding instrument was developed to assess the presence of 19 theoretical constructs. All 35 apps were downloaded and coded. The inter-rater reliability between coders was 0.996. A "1" was assigned if a construct was present in the app and "0" if it was not. Mean scores were calculated across all apps, and comparisons were made between total scores and app ratings using R. The mean behavior construct scores (BCS) across all apps was 34% (5% - 84%). Behavioral constructs for realistic goal setting (86%), time management (77%), and self-monitoring (66%) were most common. Although a positive association was observed between BCS and user ratings, this was not found to be statistically significant ( p  > 0.05). The mean persuasive technology score was 42% (20% to 80%), with higher scores for paid compared to free apps ( p  apps to support sustainable sleep hygiene practices.

  14. Commercially Available Mobile Phone Headache Diary Apps: A Systematic Review

    Science.gov (United States)

    Huguet, Anna; McGrath, Patrick J; Stinson, Jennifer N; Wheaton, Mike

    2014-01-01

    Background Headache diaries are often used by headache sufferers to self-monitor headaches. With advances in mobile technology, mobile electronic diary apps are becoming increasingly common. Objective This review aims to identify and evaluate all commercially available mobile headache diary apps for the two most popular mobile phone platforms, iOS and Android. Methods The authors developed a priori a set of 7 criteria that define an ideal headache diary app intended to help headache sufferers better understand and manage their headaches, while providing relevant data to health professionals. The app criteria were intended as minimum requirements for an acceptable headache diary app that could be prescribed by health care professionals. Each app was evaluated and scored against each criterion. Results Of the 38 apps identified, none of the apps met all 7 app criteria. The 3 highest scoring apps, meeting 5 of the app criteria, were iHeadache (developed by Better QOL), ecoHeadache (developed by ecoTouchMedia), and Headache Diary Pro (developed by Froggyware). Only 18% of the apps were created with scientific or clinical headache expertise and none of the apps reported on psychometric properties. Conclusions Despite the growing market and demand, there is a concerning lack of scientific expertise and evidence base associated with headache diary apps. PMID:25138438

  15. Mobile App Rating Scale: A New Tool for Assessing the Quality of Health Mobile Apps

    Science.gov (United States)

    Kavanagh, David J; Zelenko, Oksana; Tjondronegoro, Dian; Mani, Madhavan

    2015-01-01

    Background The use of mobile apps for health and well being promotion has grown exponentially in recent years. Yet, there is currently no app-quality assessment tool beyond “star”-ratings. Objective The objective of this study was to develop a reliable, multidimensional measure for trialling, classifying, and rating the quality of mobile health apps. Methods A literature search was conducted to identify articles containing explicit Web or app quality rating criteria published between January 2000 and January 2013. Existing criteria for the assessment of app quality were categorized by an expert panel to develop the new Mobile App Rating Scale (MARS) subscales, items, descriptors, and anchors. There were sixty well being apps that were randomly selected using an iTunes search for MARS rating. There were ten that were used to pilot the rating procedure, and the remaining 50 provided data on interrater reliability. Results There were 372 explicit criteria for assessing Web or app quality that were extracted from 25 published papers, conference proceedings, and Internet resources. There were five broad categories of criteria that were identified including four objective quality scales: engagement, functionality, aesthetics, and information quality; and one subjective quality scale; which were refined into the 23-item MARS. The MARS demonstrated excellent internal consistency (alpha = .90) and interrater reliability intraclass correlation coefficient (ICC = .79). Conclusions The MARS is a simple, objective, and reliable tool for classifying and assessing the quality of mobile health apps. It can also be used to provide a checklist for the design and development of new high quality health apps. PMID:25760773

  16. Estimating Swedish biomass energy supply

    International Nuclear Information System (INIS)

    Johansson, J.; Lundqvist, U.

    1999-01-01

    Biomass is suggested to supply an increasing amount of energy in Sweden. There have been several studies estimating the potential supply of biomass energy, including that of the Swedish Energy Commission in 1995. The Energy Commission based its estimates of biomass supply on five other analyses which presented a wide variation in estimated future supply, in large part due to differing assumptions regarding important factors. In this paper, these studies are assessed, and the estimated potential biomass energy supplies are discusses regarding prices, technical progress and energy policy. The supply of logging residues depends on the demand for wood products and is limited by ecological, technological, and economic restrictions. The supply of stemwood from early thinning for energy and of straw from cereal and oil seed production is mainly dependent upon economic considerations. One major factor for the supply of willow and reed canary grass is the size of arable land projected to be not needed for food and fodder production. Future supply of biomass energy depends on energy prices and technical progress, both of which are driven by energy policy priorities. Biomass energy has to compete with other energy sources as well as with alternative uses of biomass such as forest products and food production. Technical progress may decrease the costs of biomass energy and thus increase the competitiveness. Economic instruments, including carbon taxes and subsidies, and allocation of research and development resources, are driven by energy policy goals and can change the competitiveness of biomass energy

  17. CERN Apps meet in a forum

    CERN Multimedia

    Antonella Del Rosso

    2013-01-01

    In the fast-evolving world of mobile apps, creativity and usability are key words. For the time being, the number of CERN apps is quite limited but the situation could quickly change. An information-sharing forum set up by the IT Department is a starting point to channel your creativity with the help of experts, best practices and useful guidelines.   The CAPPS (CERN Apps) Forum was set up about a year ago. Its members come from various departments and meet every two or three months to update each other on the apps that are in preparation, share the latest news on the available software, discuss best practices and so on. “The Forum is open to anybody wanting to develop apps at CERN,” explains David Foster, Deputy Department Head and initiator of the CAPPS Forum. “Developers, communication experts and IT infrastructure experts meet and discuss various topics, from branding-related issues to coding and implementation solutions. The aim is to go forward in a coherent way...

  18. The Alzheimer Amyloid Precursor Protein (APP) and Fe65, an APP-Binding Protein, Regulate Cell Movement

    Science.gov (United States)

    Sabo, Shasta L.; Ikin, Annat F.; Buxbaum, Joseph D.; Greengard, Paul

    2001-01-01

    FE65 binds to the Alzheimer amyloid precursor protein (APP), but the function of this interaction has not been identified. Here, we report that APP and FE65 are involved in regulation of cell movement. APP and FE65 colocalize with actin and Mena, an Abl-associated signaling protein thought to regulate actin dynamics, in lamellipodia. APP and FE65 specifically concentrate with β1-integrin in dynamic adhesion sites known as focal complexes, but not in more static adhesion sites known as focal adhesions. Overexpression of APP accelerates cell migration in an MDCK cell wound–healing assay. Coexpression of APP and FE65 dramatically enhances the effect of APP on cell movement, probably by regulating the amount of APP at the cell surface. These data are consistent with a role for FE65 and APP, possibly in a Mena-containing macromolecular complex, in regulation of actin-based motility. PMID:11425871

  19. The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement.

    Science.gov (United States)

    Sabo, S L; Ikin, A F; Buxbaum, J D; Greengard, P

    2001-06-25

    FE65 binds to the Alzheimer amyloid precursor protein (APP), but the function of this interaction has not been identified. Here, we report that APP and FE65 are involved in regulation of cell movement. APP and FE65 colocalize with actin and Mena, an Abl-associated signaling protein thought to regulate actin dynamics, in lamellipodia. APP and FE65 specifically concentrate with beta 1-integrin in dynamic adhesion sites known as focal complexes, but not in more static adhesion sites known as focal adhesions. Overexpression of APP accelerates cell migration in an MDCK cell wound--healing assay. Coexpression of APP and FE65 dramatically enhances the effect of APP on cell movement, probably by regulating the amount of APP at the cell surface. These data are consistent with a role for FE65 and APP, possibly in a Mena-containing macromolecular complex, in regulation of actin-based motility.

  20. Keep Using My Health Apps: Discover Users' Perception of Health and Fitness Apps with the UTAUT2 Model.

    Science.gov (United States)

    Yuan, Shupei; Ma, Wenjuan; Kanthawala, Shaheen; Peng, Wei

    2015-09-01

    Health and fitness applications (apps) are one of the major app categories in the current mobile app market. Few studies have examined this area from the users' perspective. This study adopted the Extended Unified Theory of Acceptance and Use of Technology (UTAUT2) Model to examine the predictors of the users' intention to adopt health and fitness apps. A survey (n=317) was conducted with college-aged smartphone users at a Midwestern university in the United States. Performance expectancy, hedonic motivations, price value, and habit were significant predictors of users' intention of continued usage of health and fitness apps. However, effort expectancy, social influence, and facilitating conditions were not found to predict users' intention of continued usage of health and fitness apps. This study extends the UTATU2 Model to the mobile apps domain and provides health professions, app designers, and marketers with the insights of user experience in terms of continuously using health and fitness apps.

  1. The Business of iPhone App Development

    CERN Document Server

    Wooldridge, Dave

    2010-01-01

    The phenomenal success of the iPhone and the iPod touch has ushered in a "gold rush" for developers, but with well over 100,000 apps in the highly competitive App Store, it has become increasingly difficult for new apps to stand out in the crowd. Achieving consumer awareness and sales longevity for your iPhone app requires a lot of organization and some strategic planning. This book will show you how to incorporate marketing and business savvy into every aspect of the design and development process, giving your app the best possible chance of succeeding in the App Store. The Business

  2. Mobile web apps as an alternative to native mobile apps : The future of mobile web apps on the competitive marketplace

    OpenAIRE

    Hellbom, Kim

    2013-01-01

    Mobile applications developed with web technologies have been around for some time, but they have not yet been able to compete with native applications in form of consumer reach and user experience. Native applications have been the number one choice for con-sumers, mainly because of their powerful distribution channels and also because very few people actually know what a mobile web app is. In this thesis I will find out if mobile web apps will be able to compete with native appli-cation...

  3. Beebook: light field mapping app

    Science.gov (United States)

    De Donatis, Mauro; Di Pietro, Gianfranco; Rinnone, Fabio

    2014-05-01

    In the last decade the mobile systems for field digital mapping were developed (see Wikipedia for "Digital geologic mapping"), also against many skeptic traditional geologists. Until now, hardware was often heavy (tablet PC) and software sometime difficult also for expert GIS users. At present, the advent of light tablet and applications makes things easier, but we are far to find a whole solution for a complex survey like the geological one where you have to manage complexities such information, hypothesis, data, interpretation. Beebook is a new app for Android devices, has been developed for fast ad easy mapping work in the field trying to try to solve this problem. The main features are: • off-line raster management, GeoTIFF ed other raster format using; • on-line map visualisation (Google Maps, OSM, WMS, WFS); • SR management and conversion using PROJ.4; • vector file mash-up (KML and SQLite format); • editing of vector data on the map (lines, points, polygons); • augmented reality using "Mixare" platform; • export of vector data in KML, CSV, SQLite (Spatialite) format; • note: GPS or manual point inserting linked to other application files (pictures, spreadsheet, etc.); • form: creation, edition and filling of customized form; • GPS: status control, tracker and positioning on map; • sharing: synchronization and sharing of data, forms, positioning and other information can be done among users. The input methods are different from digital keyboard to fingers touch, from voice recording to stylus. In particular the most efficient way of inserting information is the stylus (or pen): field geologists are familiar with annotation and sketches. Therefore we suggest the use of devices with stylus. The main point is that Beebook is the first "transparent" mobile GIS for tablet and smartphone deriving from previous experience as traditional mapping and different previous digital mapping software ideation and development (MapIT, BeeGIS, Geopaparazzi

  4. MedAd-AppQ: A quality assessment tool for medication adherence apps on iOS and android platforms.

    Science.gov (United States)

    Ali, Eskinder Eshetu; Teo, Amanda Kai Sin; Goh, Sherlyn Xue Lin; Chew, Lita; Yap, Kevin Yi-Lwern

    2018-02-02

    With the recent proliferation of smartphone medication adherence applications (apps), it is increasingly more difficult for patients and clinicians to identify the most useful app. To develop a quality assessment tool for medication adherence apps, and evaluate the quality of such apps from the major app stores. In this study, a Medication Adherence App Quality assessment tool (MedAd-AppQ) was developed and two evaluators independently assessed apps that fulfilled the following criteria: availability in English, had at least a medication reminder feature, non-specific to certain disease conditions (generic apps), free of technical malfunctions and availability on both the iPhone Operating System (iOS) and Android platforms. Descriptive statistics, Mann-Whitney U test, Pearson product moment correlation and Spearman rank-order correlation were used for statistical analysis. MedAd-AppQ was designed to have 24 items (total 43 points) categorized under three sections: content reliability (11 points), feature usefulness (29 points) and feature convenience (3 points). The three sections of MedAd-AppQ were found to have inter-rater correlation coefficients of 0.801 (p-value apps (27 iOS and 25 Android), quality scores ranged between 7/43 (16.3%) and 28/43 (65.1%). There was no significant difference between the quality scores of the Android and iOS versions. None of the apps had features for self-management of side effects. Only two apps in each platform provided disease-related and/or medication information. MedAd-AppQ can be used to reliably assess the quality of adherence apps. Clinicians can use the tool in selecting apps for use by patients. Developers of adherence apps should consider features that provide therapy-related information and help patients in medications and side-effects management. Copyright © 2018 Elsevier Inc. All rights reserved.

  5. Autism Children’s App using PECS

    Directory of Open Access Journals (Sweden)

    Nareena Soomro

    2018-01-01

    Full Text Available Since autistic children suffers from learning disabilities and communication barriers, this research aim to design, develop and evaluate an Android based mobile application (app providing better learning environment with inclusion of graphical representation in a cost effective manner. This research evaluate various supporting technologies and finds Picture Exchange Communication System (PECS to be better choice for integrating with the app. Evaluation results reveal that the inclusion of PECS helped the children suffering from Autistic Spectrum Disorder (ASD to better communicate with others. The study included autistic children who do not speak, who are unintelligible and who are minimally effective communicators with their present communication system. The evolution results showed encouraging impacts of the Autism App in supporting autistic children to adapt to normal life and improve the standard of their life.

  6. Design of Trigonometry Apps for Vocational Education

    DEFF Research Database (Denmark)

    Pedersen, Jens Bjarke; Andersen, Steffen; Majgaard, Gunver

    2012-01-01

    How can smartphones apps enrich the learning of mathematicsin vocational education? This article examines how mathematics teaching can be enriched by apps using smartphone sensors such as gyroscope, compass, camera, and touch screen in a aming context. An iterative and participatory design process...... involving two classes of carpentry students from different vocational colleges resulted in two highly successful and course-relevant games based on trigonometry. Each game consists of quests and missions whose successful completion unlocks more theoretical multiple-choice exercises for the classroom...... talk about our experience in implementing our design process and subsequently summarize the pros and cons of the application and the smartphone platform and how the app developed contributes to vocational mathematics teaching....

  7. iOS app development portable genius

    CERN Document Server

    Wentk, Richard

    2012-01-01

    The essential skills and technologies needed for iOS development in one handy guide! The unprecedented popularity of iOS devices, such as the iPhone, iPad, and iPod touch, has led to a development boom. If you’re eager to become part of the action, then this is the book for you! Packed with must-have information on iOS development, this handy guide covers Objective-C, Xcode, Frameworks, and sound design principles and explains how to upload an app to the app store and integrate apps with the latest advances that Apple offers developers. The featured tips and tricks will get you up and ru

  8. Smartphone apps for spinal surgery: is technology good or evil?

    Science.gov (United States)

    Robertson, Greg A J; Wong, Seng Juong; Brady, Richard R; Subramanian, Ashok S

    2016-05-01

    The increased utilization of smartphones together with their downloadable applications (apps) provides opportunity for doctors, including spinal surgeons, to integrate such technology into clinical practice. However, the clinical reliability of the medical app sector remains questionable. We reviewed available apps themed specifically towards spinal surgery and related conditions and assessed the level of medical professional involvement in their design and content. The most popular smartphone app stores (Android, Apple, Blackberry, Windows, Samsung, Nokia) were searched for spinal surgery-themed apps, using the disease terms Spinal Surgery, Back Surgery, Spine, Disc Prolapse, Sciatica, Radiculopathy, Spinal Stenosis, Scoliosis, Spinal Fracture and Spondylolisthesis. A total of 78 individual spinal surgery themed apps were identified, of which there were six duplicates (N = 72). According to app store classifications, there were 57 (79 %) medical themed apps, 11 (15 %) health and fitness themed apps, 1 (1 %) business and 3 (4 %) education themed apps. Forty-five (63 %) apps were available for download free of charge. For those that charged access, the prices ranged from £0.62 to £47.99. Only 44 % of spinal surgery apps had customer satisfaction ratings and 56 % had named medical professional involvement in their development or content. This is the first study to specifically address the characteristics of apps related to spinal surgery. We found that nearly half of spinal surgery apps had no named medical professional involvement, raising concerns over app content and evidence base for their use. We recommend increased regulation of spinal surgical apps to improve the accountability of app content.

  9. Just a fad? Gamification in health and fitness apps.

    Science.gov (United States)

    Lister, Cameron; West, Joshua H; Cannon, Ben; Sax, Tyler; Brodegard, David

    2014-08-04

    Gamification has been a predominant focus of the health app industry in recent years. However, to our knowledge, there has yet to be a review of gamification elements in relation to health behavior constructs, or insight into the true proliferation of gamification in health apps. The objective of this study was to identify the extent to which gamification is used in health apps, and analyze gamification of health and fitness apps as a potential component of influence on a consumer's health behavior. An analysis of health and fitness apps related to physical activity and diet was conducted among apps in the Apple App Store in the winter of 2014. This analysis reviewed a sample of 132 apps for the 10 effective game elements, the 6 core components of health gamification, and 13 core health behavior constructs. A regression analysis was conducted in order to measure the correlation between health behavior constructs, gamification components, and effective game elements. This review of the most popular apps showed widespread use of gamification principles, but low adherence to any professional guidelines or industry standard. Regression analysis showed that game elements were associated with gamification (Pgamification (Pgamification was only associated with composite motivational behavior scores (Pgamification use in health and fitness apps, and the potential to impact health behavior. The results show that use of gamification in health and fitness apps has become immensely popular, as evidenced by the number of apps found in the Apple App Store containing at least some components of gamification. This shows a lack of integrating important elements of behavioral theory from the app industry, which can potentially impact the efficacy of gamification apps to change behavior. Apps represent a very promising, burgeoning market and landscape in which to disseminate health behavior change interventions. Initial results show an abundant use of gamification in health and

  10. Safety Assessment - Swedish Nuclear Power Plants

    International Nuclear Information System (INIS)

    Kjellstroem, B.

    1996-01-01

    After the reactor accident at Three Mile Island, the Swedish nuclear power plants were equipped with filtered venting of the containment. Several types of accidents can be identified where the filtered venting has no effect on the radioactive release. The probability for such accidents is hopefully very small. It is not possible however to estimate the probability accurately. Experiences gained in the last years, which have been documented in official reports from the Nuclear Power Inspectorate indicate that the probability for core melt accidents in Swedish reactors can be significantly larger than estimated earlier. A probability up to one in a thousand operating years can not be excluded. There are so far no indications that aging of the plants has contributed to an increased accident risk. Maintaining the safety level with aging nuclear power plants can however be expected to be increasingly difficult. It is concluded that the 12 Swedish plants remain a major threat for severe radioactive pollution of the Swedish environment despite measures taken since 1980 to improve their safety. Closing of the nuclear power plants is the only possibility to eliminate this threat. It is recommended that until this is done, quantitative safety goals, same for all Swedish plants, shall be defined and strictly enforced. It is also recommended that utilities distributing misleading information about nuclear power risks shall have their operating license withdrawn. 37 refs

  11. easyHealthApps: e-Health Apps dynamic generation for smartphones & tablets.

    Science.gov (United States)

    Paschou, Mersini; Sakkopoulos, Evangelos; Tsakalidis, Athanasios

    2013-06-01

    Mobile phones and especially smartphones have been embraced by a rapidly increasing number of people worldwide and this trend is expected to evolve even more in the years to come. There are numerous smartphone Apps that record critical medical data in an effort to solve a particular health issue each time. We studied such applications and not surprisingly, we have found that development and design effort is often repeated. Software patterns have been detected to exist, however re-usability has not been enforced. This leads to lost programming manpower and to increased probability of repeating bugs in Apps. Moreover, at the moment smartphone e-Health Apps demand time, effort and costs for development. Unfortunately even simple data recording Apps are practically impossible to be produced by multiple health domain users who are not developers. In this work, we propose, design and implement a simple and integrated solution which gives healthcare professionals and researchers the ability to create their own data intensive smartphone applications, independent of the desired healthcare domain. The proposed approach applies efficient software techniques that hide development from the users and enable App creation through a simple Web User Interface. The Apps produced are in native format and it is possible to dynamically receive m-Health business logic and the chosen UI. Evaluation of the proposed solution has shown that the generated Apps are functionally and UI equivalent to human-coded Apps according to a number of comparison parameters. Furthermore, e-Health professionals show particular interest in developing Apps on their own for a particular domain they focus on.

  12. Ecological economics of the Swedish Baltic empire: An essay on energy and power, 1560-1720

    International Nuclear Information System (INIS)

    Sundberg, U.

    1992-01-01

    Sweden rose from relative obscurity to become the most powerful nation in Northern Europe during the period 1560-1720 based on its prosperous metal industry: silver, copper, and steel. This essay addresses this period of history from an energy perspective and suggests, as others have, that the surplus energy of a nation is its basis for power. Sweden's energy came mainly from its forests which supplied its mines with wood and its metal-works with charcoal. This energy system, including hydropower, animal and man power, is analyzed using one of the thousands of charcoal-burners as a model for the main energy input: charcoal. The principles of sustainable use of Swedish forests are also addressed in a historical perspective. 6 figs., 9 tabs., 1 app., 40 refs

  13. Tapworthy Designing Great iPhone Apps

    CERN Document Server

    Clark, Josh

    2010-01-01

    So you've got an idea for an iPhone app -- along with everyone else on the planet. Set your app apart with elegant design, efficient usability, and a healthy dose of personality. This accessible, well-written guide shows you how to design exceptional user experiences for the iPhone and iPod Touch through practical principles and a rich collection of visual examples. Whether you're a designer, programmer, manager, or marketer, Tapworthy teaches you to "think iPhone" and helps you ask the right questions -- and get the right answers -- throughout the design process. You'll explore how consider

  14. ReciclAPP: Recicla y Gana

    OpenAIRE

    Zaragoza Linares, Cristóbal

    2018-01-01

    ReciclAPP es una aplicación para smartphones que nos permite saber en que contenedor (vidrio, plástico, orgánico, etc) o en que local de recogida una persona puede reciclar un residuo en concreto. Simplemente, mediante un buscador sencillo, el usuario teclea el nombre del residuo en cuestión y el sistema te proporciona el tipo de contenedor al cuál debería ser correctamente reciclado. Mediante la geolocalización del Smartphone, nuestra APP es capaz de mostrarte los locales de recogida más ...

  15. Review of Pocket Guide Megaliths [app

    Directory of Open Access Journals (Sweden)

    Barney Harris

    2017-09-01

    Full Text Available The Pocket Guide Megaliths app was developed by Senet Mobile UK in collaboration with The Megalithic Portal website. The app was released in 2016 and is currently available for iOS devices, such as iPhone and iPads. Pocket Guide Megaliths presents the Megalithic Portal's burgeoning worldwide database of ancient and prehistoric sites in a variety of innovative and engaging ways. It aims to act primarily as a guide to enjoying and exploring the rich prehistoric heritage of the world, though offers additional functionality for would-be monument explorers too.

  16. Empirical Analysis on the Impact of Personality Traits on Different Categories of Mobile App Adoption

    Directory of Open Access Journals (Sweden)

    Gan Chunmei

    2017-11-01

    Full Text Available [Purpose/significance] This research attempts to investigate the impact of personality traits on the adoption and time spending of mobile photography apps, mobile game apps, mobile shopping apps and mobile video apps. [Method/process] 520 valid samples were collected by questionnaires and further analyzed by using the variance analysis and correlation analysis. [Result/conclusion] The result shows that agreeableness is positively associated with the adoption of mobile photography apps; conscientiousness is negatively associated with the adoption of mobile game apps; extraversion is positively associated with the adoption of mobile shopping apps, mobile video apps and mobile photography apps; neuroticism has negative association with mobile shopping apps, mobile video apps; agreeableness has positive association with time spending on mobile video apps; conscientiousness has negative association with time spending on mobile game apps; extraversion is positively associated with time spending on mobile video apps, mobile photography apps; neuroticism has negative association with time spending on mobile video apps.

  17. Review of Tour of the Nile [iPad App

    Directory of Open Access Journals (Sweden)

    Helen Strudwick

    2013-07-01

    Full Text Available A review of the iPad app, Tour of the Nile. The app promises 'a virtual journey along the Nile Valley' plus the chance to 'handle' objects through the technology of augmented reality.

  18. Emergency Preparedness and Disaster Response: There's An App for That.

    Science.gov (United States)

    Bachmann, Daniel J; Jamison, Nathan K; Martin, Andrew; Delgado, Jose; Kman, Nicholas E

    2015-10-01

    Smartphone applications (or apps) are becoming increasingly popular with emergency responders and health care providers, as well as the public as a whole. There are thousands of medical apps available for Smartphones and tablet computers, with more added each day. These include apps to view textbooks, guidelines, medication databases, medical calculators, and radiology images. Hypothesis/Problem With an ever expanding catalog of apps that relate to disaster medicine, it is hard for both the lay public and responders to know where to turn for effective Smartphone apps. A systematic review of these apps was conducted. A search of the Apple iTunes store (Version 12; Apple Inc.; Cupertino, California USA) was performed using the following terms obtained from the PubMed Medical Subject Headings Database: Emergency Preparedness, Emergency Responders, Disaster, Disaster Planning, Disaster Medicine, Bioterrorism, Chemical Terrorism, Hazardous Materials (HazMat), and the Federal Emergency Management Agency (FEMA). After excluding any unrelated apps, a working list of apps was formed and categorized based on topics. Apps were grouped based on applicability to responders, the lay public, or regional preparedness, and were then ranked based on iTunes user reviews, value, relevance to audience, and user interface. This search revealed 683 applications and was narrowed to 219 based on relevance to the field. After grouping the apps as described above, and subsequently ranking them, the highest quality apps were determined from each group. The Community Emergency Response Teams and FEMA had the best apps for National Disaster Medical System responders. The Centers for Disease Control and Prevention (CDC) had high-quality apps for emergency responders in a variety of fields. The National Library of Medicine's Wireless Information System for Emergency Responders (WISER) app was an excellent app for HazMat responders. The American Red Cross had the most useful apps for natural

  19. Tensions in Stakeholder Relations for a Swedish Football Club

    DEFF Research Database (Denmark)

    Junghagen, Sven

    2018-01-01

    Swedish football is an industry not yet being as commercial as the big leagues and is regulated in terms of ownership of clubs. This implies a need for management of stakeholder relations for a Swedish football club. This paper identifies important stakeholders in Swedish football and discusses...

  20. Photorepair mutants of Arabidopsis

    International Nuclear Information System (INIS)

    Jiang, C.Z.; Yee, J.; Mitchell, D.L.; Britt, A.B.

    1997-01-01

    UV radiation induces two major DNA damage products, the cyclobutane pyrimidine dimer (CPD) and, at a lower frequency, the pyrimidine (6-4) pyrimidinone dimer (6-4 product). Although Escherichia coli and Saccharomyces cerevisiae produce a CPD-specific photolyase that eliminates only this class of dimer, Arabidopsis thaliana, Drosophila melanogaster, Crotalus atrox, and Xenopus laevis have recently been shown to photoreactivate both CPDs and 6-4 products. We describe the isolation and characterization of two new classes of mutants of Arabidopsis, termed uvr2 and uvr3, that are defective in the photoreactivation of CPDs and 6-4 products, respectively. We demonstrate that the CPD photolyase mutation is genetically linked to a DNA sequence encoding a type II (metazoan) CPD photolyase. In addition, we are able to generate plants in which only CPDs or 6-4 products are photoreactivated in the nuclear genome by exposing these mutants to UV light and then allowing them to repair one or the other class of dimers. This provides us with a unique opportunity to study the biological consequences of each of these two major UV-induced photoproducts in an intact living system

  1. A review of mobile apps for epilepsy self-management.

    Science.gov (United States)

    Escoffery, Cam; McGee, Robin; Bidwell, Jonathan; Sims, Christopher; Thropp, Eliana Kovitch; Frazier, Cherise; Mynatt, Elizabeth D

    2018-02-26

    Mobile health app developers increasingly are interested in supporting the daily self-care of people with chronic conditions. The purpose of this study was to review mobile applications (apps) to promote epilepsy self-management. It investigates the following: 1) the available mobile apps for epilepsy, 2) how these apps support patient education and self-management (SM), and 3) their usefulness in supporting management of epilepsy. We conducted the review in Fall 2017 and assessed apps on the Apple App Store that related to the terms "epilepsy" and "seizure". Inclusion criteria included apps (adult and pediatric) that, as follows, were: 1) developed for patients or the community; 2) made available in English, and 3) less than $5.00. Exclusion criteria included apps that were designed for dissemination of publications, focused on healthcare providers, or were available in other languages. The search resulted in 149 apps, of which 20 met the selection criteria. A team reviewed each app in terms of three sets of criteria: 1) epilepsy-specific descriptions and SM categories employed by the apps and 2) Mobile App Rating Scale (MARS) subdomain scores for reviewing engagement, functionality, esthetics, and information; and 3) behavioral change techniques. Most apps were for adults and free. Common SM domains for the apps were treatment, seizure tracking, response, and safety. A number of epilepsy apps existed, but many offered similar functionalities and incorporated few SM domains. The findings underline the need for mobile apps to cover broader domains of SM and behavioral change techniques and to be evaluated for outcomes. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Creating iPhone Apps with Cocoa Touch

    CERN Document Server

    Hockenberry, Craig

    2010-01-01

    Creating iPhone Apps with Cocoa Touch: The Mini Missing Manual walks you through developing your first iPhone App and introduces you to your programming environments and tools: Cocoa Touch, Interface Builder, Xcode, and the Objective-C programming language. If you're a Java or C developer, this eBook is your fast track to App development. This eBook is adapted from parts of iPhone App Development: The Missing Manual.

  3. A role for APP in motility and transcription?

    Science.gov (United States)

    Guénette, Suzanne Y

    2002-05-01

    Recent studies suggest two novel roles for the amyloid precursor protein (APP): APP accelerates wound healing in MDCK cells and acts in a notch-like manner to activate transcription. Both of these putative functions are dependent on the interaction of APP with the APP-binding protein FE65. Future studies are required to understand the full implications of these new findings and to determine whether therapeutic strategies for Alzheimer's disease should take these putative functions into account.

  4. Ghera: A Repository of Android App Vulnerability Benchmarks

    OpenAIRE

    Mitra, Joydeep; Ranganath, Venkatesh-Prasad

    2017-01-01

    Security of mobile apps affects the security of their users. This has fueled the development of techniques to automatically detect vulnerabilities in mobile apps and help developers secure their apps; specifically, in the context of Android platform due to openness and ubiquitousness of the platform. Despite a slew of research efforts in this space, there is no comprehensive repository of up-to-date and lean benchmarks that contain most of the known Android app vulnerabilities and, consequent...

  5. Live Speed Analysis, en app til hastighedsmålinger

    DEFF Research Database (Denmark)

    Bolet, Lars; Christensen, Peter Muhlig; Halskov-Sørensen, Asbjørn

    2013-01-01

    I et bachelorprojekt har tre studerende udviklet en app, som kan registrere og behandle hastigheder ved den såkaldte spejlmetode. App'en er siden videreudviklet, så registreringerne stedfæstes, tidstemples og uploades til en fæIIes database. App'en er frit tilgængelig. Den kan bruges af...

  6. Car App's Persuasive Design Principles and Behavior Change

    Science.gov (United States)

    Zhang, Chao; Wan, Lili; Min, Daihwan

    2016-01-01

    The emphasis of this study lies in behavior change after using car apps that assist users in using their vehicles and establishing a process for examining the interrelationship between car app's persuasive characteristics and behavior change. A categorizing method was developed and 697 car apps were investigated and classified into eight…

  7. Cleaning up That Mess: A Framework for Classifying Educational Apps

    Science.gov (United States)

    Cherner, Todd; Dix , Judy; Lee, Corey

    2014-01-01

    As tablet technologies continue to evolve, the emergence of educational applications (apps) is impacting the work of teacher educators. Beyond online lists of best apps for education and recommendations from colleagues, teacher educators have few resources available to support their teaching of how to select educational apps. In response, this…

  8. Educational Behavior Apps and Wearable Devices: Current Research and Prospects

    Science.gov (United States)

    Lowe, Heather

    2016-01-01

    Dartmouth and MIT have developed educational behavior apps and wearable devices that collect contiguous streams of data from student users. Given the consent of the user, the app collects information about a student's physical activity, sleep patterns, and location to form conjectures about social and academic behavior. These apps have the…

  9. Interactivity in Educational Apps for Young Children: A Multimodal Analysis

    Science.gov (United States)

    Blitz-Raith, Alexandra H.; Liu, Jianxin

    2017-01-01

    Interactivity is an important indicator of an educational app's reception. Since most educational apps are multimodal, it justifies a methodological initiative to understand meaningful involvement of multimodality in enacting and even amplifying interactivity in an educational app. Yet research so far has largely concentrated on algorithm…

  10. Athletic Training Education: There's an App for That

    Science.gov (United States)

    Keeley, Kim; Potteiger, Kelly; Brown, Christopher D.

    2015-01-01

    Context: Mobile applications (apps) are growing in popularity due to the increased use of smartphones. Many available apps are educational in nature and may provide both students and educators freedom for learning to occur outside of the typical classroom environment. Objective: To provide a description of relevant apps along with a brief synopsis…

  11. Using the Modern Technology That Is the "App"

    Science.gov (United States)

    Bernardelli, Alessio

    2013-01-01

    A few years ago, the sight of the letters APP would have made teachers in England think of the Assessing Pupils' Progress assessment approach introduced by the government. Now, when they see those same letters they mostly think about smartphone and tablet applications, shortened to "apps." With the thousands of apps available in the…

  12. A parental perspective on apps for young children

    NARCIS (Netherlands)

    Broekman, F.L.; Piotrowski, J.T.; Beentjes, H.W.J.; Valkenburg, P.M.

    2016-01-01

    Touchscreen applications (apps) for young children have seen increasingly high rates of growth with more than a hundred thousand now available apps. As with other media, parents play a key role in young children’s app selection and use. However, to date, we know very little about how parents select

  13. How Can iPad Apps Enrich Postgraduate Psychology Research?

    Science.gov (United States)

    Kucirkova, Natalia

    2014-01-01

    In this short Opinion piece, I outline how iPad apps can facilitate theory development, data collection, data representation and dissemination of postgraduate psychology research. I reflect on how apps supported my own postgraduate research practice and how one particular app--Our Story--enriched the individual stages of my research enquiry. I…

  14. English Language Teaching Apps: Positioning Parents and Young Learners

    Science.gov (United States)

    Chik, Alice

    2014-01-01

    Since the introduction of iPads in 2010, the sales of tablet computers and mobile applications (apps) have grown exponentially. iPads and other tablets are marketed as learning tools, and many apps target learners as young as six months old. This article reports on a research project examining the unique features of English learning apps based on…

  15. Using Apps to Support Disciplinary Literacy and Science Learning

    Science.gov (United States)

    Castek, Jill; Beach, Richard

    2013-01-01

    Apps, specialized programs used on mobile computers, can be used in innovative ways to enhance science and literacy learning. With the skilled guidance of their teachers, students can exploit app affordances for learning and acquire disciplinary literacies unique to science. This article showcases apps that help students to access information,…

  16. Low-Budget Apps for Students of All Abilities

    Science.gov (United States)

    VanWeelden, Kimberly; Heath, Julia

    2013-01-01

    With more than 850,000 apps currently on the market, there are multiple apps that can be used to help all students in music education, particularly those with special needs. This article lists low-budget apps useful for the elementary or secondary general music classroom.

  17. The Spanish Availability and Readability of Diabetes Apps.

    Science.gov (United States)

    Rodriguez, Jorge A; Singh, Karandeep

    2017-12-01

    There is growing evidence supporting the use of mobile health apps for the management of diabetes. Given the disproportionate impact of diabetes on Latinos, especially those with limited English proficiency (LEP) and low literacy, diabetes apps have the potential to address existing health disparities. Our study aimed to understand the current accessibility of diabetes apps for these populations. We searched the Android and iOS stores for the term "diabetes" to identify patient-facing diabetes apps. We reviewed the app store descriptions and user interfaces for Spanish availability. We assessed the readability of the descriptions in English and Spanish using the Lexile Analyzer and the Flesch-Kincaid Reading Grade Level. Overall, in reviewing both app stores, 30% (28/92) of apps had descriptions available in Spanish, of which 41% (18/44) of Android apps were available in Spanish and 21% (10/48) iOS apps were available in Spanish. In addition, the readability of 94% (90/96) for the app store descriptions was above the recommended reading level for patient education material in English and Spanish. The overall kappa coefficient for app translation quality assessment was .72, reflecting moderate interrater agreement. Despite the evidence supporting the use of diabetes apps, they do not cater to the language needs of LEP Latino patients.

  18. e-Medication met behulp van apps : Gebruik en gebruikerservaringen

    NARCIS (Netherlands)

    van Kerkhof LWM; van de Laar K; Schooneveldt B; Hegger I; EVG; V&Z

    2015-01-01

    De afgelopen jaren zijn er veel apps voor het gebruik van medicijnen beschikbaar gekomen, voor zowel professionals als burgers. In hoeverre deze apps worden gewaardeerd, hangt vooral af van het gebruiksgemak. Dit blijkt uit onderzoek van het RIVM onder gebruikers van apps die voor diabetici en

  19. Mobile Phone Apps to Improve Medication Adherence: A Systematic Stepwise Process to Identify High-Quality Apps.

    Science.gov (United States)

    Santo, Karla; Richtering, Sarah S; Chalmers, John; Thiagalingam, Aravinda; Chow, Clara K; Redfern, Julie

    2016-12-02

    There are a growing number of mobile phone apps available to support people in taking their medications and to improve medication adherence. However, little is known about how these apps differ in terms of features, quality, and effectiveness. We aimed to systematically review the medication reminder apps available in the Australian iTunes store and Google Play to assess their features and their quality in order to identify high-quality apps. This review was conducted in a similar manner to a systematic review by using a stepwise approach that included (1) a search strategy; (2) eligibility assessment; (3) app selection process through an initial screening of all retrieved apps and full app review of the included apps; (4) data extraction using a predefined set of features considered important or desirable in medication reminder apps; (5) analysis by classifying the apps as basic and advanced medication reminder apps and scoring and ranking them; and (6) a quality assessment by using the Mobile App Rating Scale (MARS), a reliable tool to assess mobile health apps. We identified 272 medication reminder apps, of which 152 were found only in Google Play, 87 only in iTunes, and 33 in both app stores. Apps found in Google Play had more customer reviews, higher star ratings, and lower cost compared with apps in iTunes. Only 109 apps were available for free and 124 were recently updated in 2015 or 2016. Overall, the median number of features per app was 3.0 (interquartile range 4.0) and only 18 apps had ≥9 of the 17 desirable features. The most common features were flexible scheduling that was present in 56.3% (153/272) of the included apps, medication tracking history in 54.8% (149/272), snooze option in 34.9% (95/272), and visual aids in 32.4% (88/272). We classified 54.8% (149/272) of the included apps as advanced medication reminder apps and 45.2% (123/272) as basic medication reminder apps. The advanced apps had a higher number of features per app compared with the

  20. Mobile Apps and Transportation : A Review of Smartphone Apps and a Study of User Response to Multimodal Traveler Information.

    Science.gov (United States)

    2016-10-01

    In recent years, technological and social forces have pushed smartphone applications (apps) from the fringe to the mainstream. Understanding the role of transportation apps in urban mobility is important for policy development and transportation plan...

  1. The App Squad: SLJ's Advisors Weigh in on Kids' Book Apps

    Science.gov (United States)

    Ishizuka, Kathy

    2011-01-01

    In this article, "School Library Journal's" ("SLJ") advisors talk about book apps for kids. They discuss what they like, what one should look for in discerning the best for kids and teens, and where this all might be headed.

  2. Data Exchanges in Mobile News Apps

    DEFF Research Database (Denmark)

    Kammer, Aske; Wallberg, Filip

    This paper maps the flows of data to and from third-party actors when users access content in mobile news apps. This way, it analyzes the strategic networks of collaboration and data exchange that news organizations engage in in the digital economy, expanding the traditional two-sided model...

  3. App Studies : Platform Rules and Methodological Challenges

    NARCIS (Netherlands)

    Gerlitz, C.; Helmond, A.; van der Vlist, F.; Weltevrede, E.; De Groote, S.; Majmundar, P.

    2016-01-01

    The panel engages with conceptual and methodological challenges within a specific area of ‘internet rules’, namely the space of mobile apps. Whereas the web was set out to function as a ‘generative’ and open technology facilitating the production of unanticipated services and applications, the

  4. Smart phones and apps application in dermatology

    Directory of Open Access Journals (Sweden)

    Meltem Önder

    2013-03-01

    Full Text Available Mobile phones are a device that is more than just a phone and more than a personel digital assistant.Nowadays a phone is as a powerful handheld computer,camera,video recorder,media player,GPS receiver,MP3 player,radio and as well as a communication tool. Smartphones (mobile phones with advanced computing capability are rapidly gaining new use with the advent of dowloadable applications known as ‘Apps’. There are a lot of medical apps avaliable.Dermatology themed smartphone apps were provided as reference materials,illustrated databases of common skin conditions for accessing online versions of popular dermatology textbook and journals;dermatology based questionnairs; including disease severity scoring calculators and /or providing automated photo analysers for skin lesions / as an electronic dermoscopy. Most of the apps applications are free of charge and can be easily dowloaded to smartphones. Furthermore the possibility to send and save both text and images by this technology seems perfectly tailored to dermatology.Recently electronic teaching and learning via smartphones are becoming very popular for medical students aswell. However there is relatively little research on medical uses and potential roles of them in dermatology.This article summarizes the curent trends in the ‘smartphone market’ and takes a glance at some dermatology apps ‘which are currently available.

  5. Expanding Analytical Perspectives on Children's Picturebook Apps

    Science.gov (United States)

    Aguilera, Earl; Kachorsky, Dani; Gee, Elisabeth; Serafini, Frank

    2016-01-01

    Research on the nature and impact of book apps or e-reading in general is still limited and informed by diverse assumptions about the nature of these new "texts," the varied forms of engagement and meaning-making associated with them, and their implications for understanding literacy and learning in the digital age. The purpose of this…

  6. Ambassadors of the Swedish Nation: National Images in the Teaching of the Swedish Lecturers in Germany 1918-1945

    Science.gov (United States)

    Åkerlund, Andreas

    2015-01-01

    This article analyses the teaching of Swedish language lecturers active in Germany during the first half of the twentieth century. It shows the centrality of literature and literary constructions and analyses images of Swedishness and the Swedish nation present in the teaching material of that time in relation to the national image present in…

  7. Mobile Apps in Oncology: A Survey on Health Care Professionals? Attitude Toward Telemedicine, mHealth, and Oncological Apps

    OpenAIRE

    Kessel, Kerstin A; Vogel, Marco ME; Schmidt-Graf, Friederike; Combs, Stephanie E

    2016-01-01

    Background Mobile apps are an evolving trend in the medical field. To date, few apps in an oncological context exist. Objective The aim was to analyze the attitude of health care professionals (HCPs) toward telemedicine, mHealth, and mobile apps in the field of oncology. Methods We developed and conducted an online survey with 24 questions evaluating HCPs? general attitude toward telemedicine and patients using medical mobile apps. Specific questions on the possible functionality for patients...

  8. Developing smartphone apps for behavioural studies: The AlcoRisk app case study.

    Science.gov (United States)

    Smith, Anthony; de Salas, Kristy; Lewis, Ian; Schüz, Benjamin

    2017-08-01

    Smartphone apps have emerged as valuable research tools to sample human behaviours at their time of occurrence within natural environments. Human behaviour sampling methods, such as Ecological Momentary Assessment (EMA), aim to facilitate research that is situated in ecologically valid real world environments rather than laboratory environments. Researchers have trialled a range of EMA smartphone apps to sample human behaviours such as dieting, physical activity and smoking. Software development processes for EMA smartphones apps, however, are not widely documented with little guidance provided for the integration of complex multidisciplinary behavioural and technical fields. In this paper, the AlcoRisk app for studying alcohol consumption and risk taking tendencies is presented alongside a software development process that integrates these multidisciplinary fields. The software development process consists of three stages including requirements analysis, feature and interface design followed by app implementation. Results from a preliminary feasibility study support the efficacy of the AlcoRisk app's software development process. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Apps in therapy: occupational therapists' use and opinions.

    Science.gov (United States)

    Seifert, Anna M; Stotz, Nicole; Metz, Alexia E

    2017-11-01

    To gather information on occupational therapy practitioners' use and opinions of apps, an online survey was distributed to occupational therapy practitioners licensed in the state of Ohio. The survey sought information regarding clinical populations and skill areas for which apps are used, potential barriers to use of apps and preferred apps/app features. OTs working in medical and education-based settings and with clients of all ages responded to the survey. Over half (53%) reported not using apps in therapy, with "not having access to the technology at work" being the leading reason endorsed. Of practitioners who did report using apps, the majority used them with ≤25% of their case load and primarily used tablets to do so. Clinicians indicated that they use apps for a wide variety of reasons, including to promote skill building and to support the therapeutic process. Preferred features included the ability to grade difficulty up/down, multiple uses and accurate feedback. Recommendations from peers were the most commonly reported way respondents found new apps. The results suggest that occupational therapy practitioners employ clinical reasoning when implementing apps in therapy. Possible ways to improve access to apps for therapists who would like to implement them are discussed. Implications for Rehabilitation Many occupational therapy practitioners are using apps with at least a portion of their caseloads. Therapists select apps based on peer recommendations, most commonly selecting those which promote skill building and support the therapeutic process. More therapists might make use of apps if potential barriers were reduced or eliminated, including availability of technology in the clinical practice setting, therapist training and education, therapist input into app development and an enhanced evidence base.

  10. Isozyme differences in barley mutants

    International Nuclear Information System (INIS)

    AI-Jibouri, A.A.M.; Dham, K.M.

    1990-01-01

    Full text: Thirty mutants (M 11 ) of barley (Hordeum vulgare L.) induced by physical and chemical mutagens were analysed for isozyme composition using polyacrylamide gel electrophoresis. Results show that these mutants were different in the isozymes leucine aminopeptidase, esterase and peroxidase. The differences included the number of forms of each enzyme, relative mobility value and their intensity on the gel. Glutamate oxaloacetate transaminase isozyme was found in six molecular forms and these forms were similar in all mutants. (author)

  11. Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding

    Directory of Open Access Journals (Sweden)

    Lovestone Simon

    2007-12-01

    Full Text Available Abstract Background Shedding of the Alzheimer amyloid precursor protein (APP ectodomain can be accelerated by phorbol esters, compounds that act via protein kinase C (PKC or through unconventional phorbol-binding proteins such as Munc13-1. We have previously demonstrated that application of phorbol esters or purified PKC potentiates budding of APP-bearing secretory vesicles at the trans-Golgi network (TGN and toward the plasma membrane where APP becomes a substrate for enzymes responsible for shedding, known collectively as α-secretase(s. However, molecular identification of the presumptive "phospho-state-sensitive modulators of ectodomain shedding" (PMES responsible for regulated shedding has been challenging. Here, we examined the effects on APP ectodomain shedding of four phorbol-sensitive proteins involved in regulation of vesicular membrane trafficking of APP: Munc13-1, Munc18, NSF, and Eve-1. Results Overexpression of either phorbol-sensitive wildtype Munc13-1 or phorbol-insensitive Munc13-1 H567K resulted in increased basal APP ectodomain shedding. However, in contrast to the report of Roßner et al (2004, phorbol ester-dependent APP ectodomain shedding from cells overexpressing APP and Munc13-1 wildtype was indistinguishable from that observed following application of phorbol to cells overexpressing APP and Munc13-1 H567K mutant. This pattern of similar effects on basal and stimulated APP shedding was also observed for Munc18 and NSF. Eve-1, an ADAM adaptor protein reported to be essential for PKC-regulated shedding of pro-EGF, was found to play no obvious role in regulated shedding of sAPPα. Conclusion Our results indicate that, in the HEK293 system, Munc13-1, Munc18, NSF, and EVE-1 fail to meet essential criteria for identity as PMES for APP.

  12. Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding.

    Science.gov (United States)

    Ikin, Annat F; Causevic, Mirsada; Pedrini, Steve; Benson, Lyndsey S; Buxbaum, Joseph D; Suzuki, Toshiharu; Lovestone, Simon; Higashiyama, Shigeki; Mustelin, Tomas; Burgoyne, Robert D; Gandy, Sam

    2007-12-09

    Shedding of the Alzheimer amyloid precursor protein (APP) ectodomain can be accelerated by phorbol esters, compounds that act via protein kinase C (PKC) or through unconventional phorbol-binding proteins such as Munc13-1. We have previously demonstrated that application of phorbol esters or purified PKC potentiates budding of APP-bearing secretory vesicles at the trans-Golgi network (TGN) and toward the plasma membrane where APP becomes a substrate for enzymes responsible for shedding, known collectively as alpha-secretase(s). However, molecular identification of the presumptive "phospho-state-sensitive modulators of ectodomain shedding" (PMES) responsible for regulated shedding has been challenging. Here, we examined the effects on APP ectodomain shedding of four phorbol-sensitive proteins involved in regulation of vesicular membrane trafficking of APP: Munc13-1, Munc18, NSF, and Eve-1. Overexpression of either phorbol-sensitive wildtype Munc13-1 or phorbol-insensitive Munc13-1 H567K resulted in increased basal APP ectodomain shedding. However, in contrast to the report of Rossner et al (2004), phorbol ester-dependent APP ectodomain shedding from cells overexpressing APP and Munc13-1 wildtype was indistinguishable from that observed following application of phorbol to cells overexpressing APP and Munc13-1 H567K mutant. This pattern of similar effects on basal and stimulated APP shedding was also observed for Munc18 and NSF. Eve-1, an ADAM adaptor protein reported to be essential for PKC-regulated shedding of pro-EGF, was found to play no obvious role in regulated shedding of sAPPalpha. Our results indicate that, in the HEK293 system, Munc13-1, Munc18, NSF, and EVE-1 fail to meet essential criteria for identity as PMES for APP.

  13. Swedish Fashion 1930–1960 : Rethinking the Swedish Textile and Clothing Industry

    OpenAIRE

    Kyaga, Ulrika

    2017-01-01

    The aim of this thesis is to explore the development of Swedish fashion between 1930 and 1960 by examining the textile and clothing industry from the wider perspective of fashion production. It was during this period that Sweden was transformed into a leading industrial nation, which laid the foundation for increased prosperity in the post-war period. This historical and empirical study is predominantly based on systematic analysis of Swedish official statistics and close reading of the fashi...

  14. Training Entrepreneurship at Universities: A Swedish Case.

    Science.gov (United States)

    Klofsten, Magnus

    2000-01-01

    The Entrepreneurship and New Business Development Program trains Swedish individuals in the startup of technology- or knowledge-based enterprises. Built on the characteristics of entrepreneurial behavior, the program features a holistic outlook, a network of established entrepreneurs, mentoring, a mix of theory and practice, and focus on the…

  15. Science communication and the Swedish acrylamide "alarm".

    Science.gov (United States)

    Lofstedt, Ragnar E

    2003-01-01

    On April 24, 2002 the Swedish National Food Administration along with a group of researchers at the University of Stockholm raised an alarm regarding potential health risks associated with eating fried and baked foods such as potatoes and bread. Scientists had found high levels of acrylamide (up to 500 times more acrylamide than that allowed in drinking water by the World Health Organisation), a substance widely believed to cause cancer, in cooked high starch foods. The outcomes of this "alarm" were immediate. In Sweden sales of chips fell by 30-50 percent over a 3-day period following the press conference, and share prices among several fried food manufacturers fell substantially, as stock analysts were fearful that consumption of fried foods would decrease significantly. Four days after the press conference, however, consumers began eating fried food as normal and a number of researchers and journalists in Sweden and elsewhere took the view that the alarm had been both exaggerated and ill placed. In this study, I evaluate the science communication process associated with the scare, based on a content analysis of a select group of Swedish broad sheets from just previous to the April 2002 press conference to the present time (December 2002). In addition, the study is based on interviews with the various Swedish regulators involved in the process itself (in particular at the Swedish National Food Administration) as well as with the scientists responsible for the study at Stockholm University and relevant journalists and politicians.

  16. Strontium 90 in Swedish dairy milk 1978

    International Nuclear Information System (INIS)

    Gillberg-Wickman, M.; Oestergren, I.

    1980-01-01

    The contamination of strontium-90 in Swedish milk during 1978 is practically the same as in 1977. The country-wide mean ratio of strontium-90 to calcium in milk is 0.12 Bq 90 Sr(gCa) -1 , based on monthly determinations of samples obtained from 8 dairy plants situated throughout the country. (author)

  17. Mathematics and Didactic Contract in Swedish Preschools

    Science.gov (United States)

    Delacour, Laurence

    2016-01-01

    The purpose of this article is to study and analyse how a teacher implements an outdoor realistic problem situation for children aged 4-5 in a Swedish preschool. By an "outdoor realistic problem situation", I mean a situation initiated by a teacher in which children come into contact with mathematical concepts and in which the outside…

  18. Leisure, Government and Governance: A Swedish Perspective

    Science.gov (United States)

    Lindstrom, Lisbeth

    2011-01-01

    The leisure sector has witnessed a tremendous expansion since 1960. The purpose of this article is to analyse the decisions and goals of Swedish government policy during the period 1962 to 2005. The empirical analysis covers government Propositions and governmental investigations. The fields covered are sports, culture, exercise, tourism and…

  19. SWEDISH CRIME FICTION AS SOCIALLY INVOLVED LITERATURE

    Directory of Open Access Journals (Sweden)

    Monika Samsel-Chojnacka

    2011-01-01

    Full Text Available Swedish crime novel has been transforming for many years to become more socially involved. The ambition of many writers is not only to entertain the readers but also to participating in the social debate, criticizing the political and economical system, focusing on important issues such as violence against women, exploitation of working class by the privileged ruling class, the problems of a modern family and the situation of immigrants. Since the moment when in the mid 60’s two journalists Maj Sjöwall and Per Wahlöö decided to use popular literature to spread social matters many other Swedish writers have decided to follow their way. Some of them are journalists – like Liza Marklund, Börge Hellström and Anders Roslund or Stieg Larsson. Their novels as well as the ones written by Henning Mannkel on Kurt Wallander have become crucial evidence of changes of Swedish society in the past twenty years. Modern Swedish crime fiction illustrates the population in the model fashion that is the reason why it can become one of the interests of the sociology of literature.

  20. Gender Integration and the Swedish Armed Forces

    DEFF Research Database (Denmark)

    Gustafsson, Daniel Marcus Sunil

    the organisation to reinforce the notion of women as inferior and subordinate to men, whereby the external hegemony is believed to be restored. Likewise, male Swedish peacekeepers’ demand for prostitution during international peacekeeping missions is explained in terms of a need to confirm manhood and as homo...

  1. Market reforms in Swedish health care

    DEFF Research Database (Denmark)

    Diderichsen, Finn

    1993-01-01

    This report presents the main characteristics of reforms in the Swedish health services, as exemplified by the "Stockholm Model" introduced in 1992 in Stockholm county. The author discusses the motives behind these reforms, the already-evident increases in costs that are occurring, and the effect...... of these reforms on public support for the welfare state....

  2. The Widening Gap--A Swedish Perspective

    Science.gov (United States)

    Brandell, Gerd; Hemmi, Kristi; Thunberg, Hans

    2008-01-01

    Transition problems from secondary to tertiary level in mathematics have been a recurrent issue in Sweden. This paper summarises the development during the last decades. Results from two recent research studies that illuminate the transition problem are presented. The first one, based on empirical data from a major Swedish technical university,…

  3. A Smartphone App for Improvement of Colonoscopy Preparation (ColoprAPP): Development and Feasibility Study.

    Science.gov (United States)

    Walter, Benjamin; Schmid, Roland; von Delius, Stefan

    2017-09-20

    Optimal bowel preparation is one of the major cornerstones for quality of colonoscopy. But poor bowel preparation still occurs in 10% to 25% of all patients. To optimize patient guidance, we developed a new smartphone app (ColoprAPP) for Android smartphones which guides and accompanies the patient starting 4 days before colonoscopy throughout the whole colonoscopy preparation procedure. The objective of this study was to assess the function of a newly developed smartphone app for supporting colonoscopy preparation. We carried out a prospective feasibility study including 25 patients undergoing outpatient colonoscopy at our hospital. As a control, we retrieved the data of 25 patients undergoing outpatient colonoscopy matching in age, sex, and indication for colonoscopy from our colonoscopy database. Patients were asked to download the smartphone app, ColoprAPP, in addition to being given the regular colonoscopy preparation leaflet. All colonoscopies were performed in the morning after using a split-dose preparation containing a polyethlene glycol-based purgative. The study was designed to test feasibility of the prototype, evaluate grade of bowel cleanliness (Boston bowel preparation scale [BBPS]), and assess patient satisfaction with the app. The smartphone app use was feasible in all patients. BBPS count as a marker for grade of bowel preparation was significantly higher in the smartphone app-supported group (mean 8.1 [SD 0.3] vs 7.1 [SD 0.4], P=.02). Left (mean 2.8 [SD 0.1] vs 2.4 [SD 0.11], P=.02) and transverse colon (mean 2.8 [SD 0.07] vs 2.4 [SD 0.11], Papp-supported group than in controls. Patient satisfaction with a smartphone app-supported colonoscopy preparation was high with an average numeric rating scale score for usefulness of 8.2 (visual analog scale 1-10). A novel developed smartphone app for reinforced education of bowel cleansing was feasible and led to high BBPS scores and patient satisfaction. ClinicalTrials.gov NCT02512328; https

  4. Parent Education is Changing: A Review of Smartphone Apps.

    Science.gov (United States)

    Davis, Deborah Winders; Logsdon, M Cynthia; Vogt, Krista; Rushton, Jeff; Myers, John; Lauf, Adrian; Hogan, Felicia

    The purpose was to critique existing parenting apps using established criteria and health literacy guidelines. Descriptive methodology was used. The Apple App Store was searched using the terms parenting, child health, and infant health. To be included, the apps had to have relevant content (parenting, child health, or infant health), be in English, and contain parent education. After eliminating apps that failed to meet inclusion criteria from the original 203 apps, 46 apps were reviewed. The Patient Education Materials Assessment Tool was used to evaluate the health literacy subscales called Understandability and Actionability. Content analysis included Authority, Objectivity, Accuracy, Timeliness, and Usability. The majority of the apps (70%) were in English only. The price ranged from free to $4.99. The purpose, target audience, and topics varied. Although all included apps were for parents, some were for more targeted groups of parents. The source of the information was not presented in 26% of the apps. Most apps took the user to a Web site or an article to read. Functionality of the apps was limited, with none of them providing a customized experience. Much development and research is needed before mobile health (mHealth) solutions can be recommended by nurses caring for new parents. It is critical that consumers and interdisciplinary professionals be involved in the early design phase of the product to ensure that the end product is acceptable and usable and that it will lead to healthy behaviors.

  5. Development of a Mobile App for Family Planning Providers.

    Science.gov (United States)

    Halsall, Viannella; Rogers, Jennifer; Witt, Jacki; Song, Sejun; Nguyen, Hoang Duc Huy; Kelly, Patricia

    To provide an overview of lessons learned during the development process of an app for iOS and Android based on national recommendations for providing quality family planning services. After a review of existing apps was conducted to determine whether an app of clinical recommendations for family planning existed, a team of clinicians, training specialists, and app developers created a resource app by first drafting a comprehensive content map. A prototype of the app was then pilot tested using smart tablets by a volunteer convenience sample of women's healthcare professionals. Outcomes measured included usability, acceptability, download analytics, and satisfaction by clinicians as reported through an investigator-developed tool. Sixty-nine professionals tested a prototype of the app, and completed a user satisfaction tool. Overall, user feedback was positive, and a zoom function was added to the final version as a result of the pilot test. Within 3 months of being publicly available, the app was downloaded 677 times, with 97% of downloads occurring on smart phones, 76% downloads occurring on iOS devices, and 24% on Android devices. This trend persisted throughout the following 3 months. Clinicians with an interest in developing an app should consider a team approach to development, pilot test the app prior to wider distribution, and develop a web-based version of the app to be used by clinicians who are unable to access smart devices in their practice setting.

  6. App Reviews: Breaking the User and Developer Language Barrier

    KAUST Repository

    Hoon, Leonard

    2015-10-22

    Apple, Google and third party developers offer apps across over twenty categories for various smart mobile devices. Offered exclusively through the App Store and Google Play, each app allows users to review the app and their experience with it. Current literature offers a general statistical picture of these reviews, and a broad overview of the nature of discontent of apps. However, we do not yet have a good framework to classify user reviews against known software quality attributes like performance or usability. In order to close this gap, in this paper, we develop an ontology encompassing software attributes derived from software quality models. This decomposes into approximately five thousand words that users employ to review apps. By identifying a consistent set of vocabulary that users communicate with, we can sanitise large datasets to extract stakeholder actionable information from reviews. The findings offered in this paper assists future app review analysis by bridging end-user communication and software engineering vocabulary.

  7. Smartphone Applications - Idea sourcing, and app development: Implications for firms

    Directory of Open Access Journals (Sweden)

    Debbie Vigar-Ellis

    2014-05-01

    Full Text Available With the dramatic increase in smartphone usage and the consequent increase in applications (apps for these smartphones, organisations are constantly looking for new apps to offer customers as well as employees.  Information Systems (IS departments of organisations have traditionally been tasked with the acquisition and/or development of such information technologies within organisations.  This research aimed to determine from IS managers, the smartphone app usage in firms, the sources of app ideas and the locations for app development.  It also investigated various aspects of the success or otherwise of the development process.  Results indicate that while most ideas for apps currently come from IS and marketing departments within the organisation, and development of apps is also done mainly within the organisation , these development strategies are not necessarily the most effective.  Managerial implications are discussed.

  8. Prevalence of footrot in Swedish slaughter lambs

    Directory of Open Access Journals (Sweden)

    Nyman Ann-Kristin J

    2011-04-01

    Full Text Available Abstract Background Footrot is a world-wide contagious disease in sheep and goats. It is an infection of the epidermis of the interdigital skin, and the germinal layers of the horn tissue of the feet. The first case of footrot in Swedish sheep was diagnosed in 2004. Due to difficulties in distinguishing benign footrot from early cases of virulent footrot and because there is no possibility for virulence testing of strains of Dichelobacter nodosus in Sweden, the diagnosis is based of the presence or absence of clinical signs of footrot in sheep flocks. Ever since the first diagnosed case the Swedish Animal Health Service has worked intensively to stop the spread of infection and control the disease at flock level. However, to continue this work effectively it is important to have knowledge about the distribution of the disease both nationally and regionally. Therefore, the aims of this study were to estimate the prevalence of footrot in Swedish lambs at abattoirs and to assess the geographical distribution of the disease. Methods A prevalence study on footrot in Swedish lambs was performed by visual examination of 2000 feet from 500 lambs submitted from six slaughter houses. Each foot was scored according to a 0 to 5 scoring system, where feet with score ≥2 were defined as having footrot. Moreover, samples from feet with footrot were examined for Dichelobacter nodosus by culture and PCR. Results The prevalence of footrot at the individual sheep level was 5.8%, and Dichelobacter nodosus was found by culture and PCR in 83% and 97% of the samples from feet with footrot, respectively. Some minor differences in geographical distribution of footrot were found in this study. Conclusions In a national context, the findings indicate that footrot is fairly common in Swedish slaughter lambs, and should be regarded seriously.

  9. Apps for People With Rheumatoid Arthritis to Monitor Their Disease Activity: A Review of Apps for Best Practice and Quality

    Science.gov (United States)

    Townsley, Hermaleigh; White, Bonnie; Langlotz, Tobias; Taylor, William J

    2017-01-01

    Background Rheumatoid arthritis (RA) is a chronic inflammatory arthritis requiring long-term treatment with regular monitoring by a rheumatologist to achieve good health outcomes. Since people with RA may wish to monitor their own disease activity with a smartphone app, it is important to understand the functions and quality of apps for this purpose. Objective The aim of our study was to assess the features and quality of apps to assist people to monitor their RA disease activity by (1) summarizing the available apps, particularly the instruments used for measurement of RA disease activity; (2) comparing the app features with American College of Rheumatology and European League against Rheumatism (ACR and EULAR) guidelines for monitoring of RA disease activity; and (3) rating app quality with the Mobile App Rating Scale (MARS). Methods Systematic searches of the New Zealand iTunes and Google Play app stores were used to identify all apps for monitoring of RA disease activity that could be used by people with RA. The apps were described by both key metadata and app functionality. App adherence with recommendations for monitoring of RA disease activity in clinical practice was evaluated by identifying whether apps included calculation of a validated composite disease activity measure and recorded results for future retrieval. App quality was assessed by 2 independent reviewers using the MARS. Results The search identified 721 apps in the Google Play store and 216 in the iTunes store, of which 19 unique apps met criteria for inclusion (8 from both app stores, 8 iTunes, and 3 Google Play). In total, 14 apps included at least one validated instrument measuring RA disease activity; 7 of 11 apps that allowed users to enter a joint count used the standard 28 swollen and tender joint count; 8 apps included at least one ACR and EULAR-recommended RA composite disease activity (CDA) measure; and 10 apps included data storage and retrieval. Only 1 app, Arthritis Power, included

  10. Results of the Clinician Apps Survey, How Clinicians Working With Patients With Diabetes and Obesity Use Mobile Health Apps.

    Science.gov (United States)

    Karduck, Justine; Chapman-Novakofski, Karen

    2018-01-01

    To develop and administer a questionnaire to determine what factors may be associated with app use (including frequency of use, reasons to recommend to clients/patients, perceived effectiveness on health, health aspects used, features, and types of apps) by clinicians working in diabetes and weight management patient care settings. The Clinician Apps Survey was developed and contained 3 question domains (smartphone apps use, behavior theory in counseling sessions, and demographics) to explore frequency, types, preferred features, benefits/barriers of using apps, counseling techniques used, and clinician demographics. Clinicians (n = 719) were recruited to complete the online survey through 4 dietetics and diabetes professional groups. Clinician use and preferences for health-related apps for personal reasons and in patient care settings were determined, and comparisons were made between high and non-app users. Descriptive statistics were used with current practices and attitudes about apps. Chi-square test of independence compared those using apps both personally and professionally (app enthusiasts) vs those with no app use. There were more app enthusiasts (53%; n = 380) than non-app users (20%; n = 145). Whereas 68% recommended pen/paper methods for diet and physical activity monitoring, 62% recommended apps. Most agreed that apps were superior to traditional methods for patients to track dietary intake (62%) and physical activity (58%), make better food choices (34%), lose weight (45%), and track blood glucose (43%). App enthusiasts used the American Association of Diabetes Educators self-care guidelines (P = .001) and advanced counseling techniques (eg, motivational interviewing) more often than did non-app users (P Apps most frequently recommended to clients were MyFitnessPal (n = 425), CalorieKing (n = 356), and Fitbit (n = 312). Health-related smartphone apps are being widely used and recommended to patients with diabetes and obesity by

  11. The Business of iPhone and iPad App Development Making and Marketing Apps That Succeed

    CERN Document Server

    Wooldridge, Dave

    2011-01-01

    The phenomenal success of the iPhone, iPad and the iPod touch has ushered in a "gold rush" for developers, but with well over 300,000 apps in the highly competitive App Store, it has become increasingly difficult for new apps to stand out in the crowd. Achieving consumer awareness and sales longevity for your iOS app requires a lot of organization and some strategic planning. Updated and expanded for iOS 4, this bestselling book will show you how to incorporate marketing and business savvy into every aspect of the design and development process, giving your app the best possible chance of

  12. Apps and Mobile Support Services in Canadian Academic Medical Libraries

    Directory of Open Access Journals (Sweden)

    Tess Grynoch

    2016-12-01

    Full Text Available Objective: To examine how Canadian academic medical libraries are supporting mobile apps, what apps are currently being provided by these libraries, and what types of promotion are being used. Methods: A survey of the library websites for the 17 medical schools in Canada was completed. For each library website surveyed, the medical apps listed on the website, any services mentioned through this medium, and any type of app promotion events were noted. When Facebook and Twitter accounts were evident, the tweets were searched and the past two years of Facebook posts scanned for mention of medical apps or mobile services/events. Results: All seventeen academic medical libraries had lists of mobile medical apps with a large range in the number of medical relevant apps (average=31, median= 23. A total of 275 different apps were noted and the apps covered a wide range of subjects. Five of the 14 Facebook accounts scanned had posts about medical apps in the past two years while 11 of the 15 Twitter accounts had tweets about medical apps. Social media was only one of the many promotional methods noted. Outside of the app lists and mobile resources guides, Canadian academic medical libraries are providing workshops, presentations, and drop-in sessions for mobile medical apps. Conclusion: While librarians cannot simply compare mobile services and resources between academic medical libraries without factoring in a number of other circumstances, librarians can learn from mobile resources strategies employed at other libraries, such as using research guides to increase medical app literacy.

  13. Evaluation of tall rice mutant

    International Nuclear Information System (INIS)

    Hakim, L.; Azam, M.A.; Miah, A.J.; Mansur, M.A.; Akanda, H.R.

    1989-01-01

    One tall mutant (Mut NS1) of rice variety Nizersail was put to multilocation on-farm trial. It showed improvement over the parent in respect of by earlier maturity and higher grain yield at all locations and thus it appears as an improved mutant of Nizersail. (author). 6 refs

  14. Designing platform independent mobile apps and services

    CERN Document Server

    Heckman, Rocky

    2016-01-01

    This book explains how to help create an innovative and future proof architecture for mobile apps by introducing practical approaches to increase the value and flexibility of their service layers and reduce their delivery time. Designing Platform Independent Mobile Apps and Services begins by describing the mobile computing landscape and previous attempts at cross platform development. Platform independent mobile technologies and development strategies are described in chapter two and three. Communication protocols, details of a recommended five layer architecture, service layers, and the data abstraction layer are also introduced in these chapters. Cross platform languages and multi-client development tools for the User Interface (UI) layer, as well as message processing patterns and message routing of the Service Int rface (SI) layer are explained in chapter four and five. Ways to design the service layer for mobile computing, using Command Query Responsibility Segregation (CQRS) and the Data Abstraction La...

  15. Interrater Reliability of mHealth App Rating Measures: Analysis of Top Depression and Smoking Cessation Apps.

    Science.gov (United States)

    Powell, Adam C; Torous, John; Chan, Steven; Raynor, Geoffrey Stephen; Shwarts, Erik; Shanahan, Meghan; Landman, Adam B

    2016-02-10

    There are over 165,000 mHealth apps currently available to patients, but few have undergone an external quality review. Furthermore, no standardized review method exists, and little has been done to examine the consistency of the evaluation systems themselves. We sought to determine which measures for evaluating the quality of mHealth apps have the greatest interrater reliability. We identified 22 measures for evaluating the quality of apps from the literature. A panel of 6 reviewers reviewed the top 10 depression apps and 10 smoking cessation apps from the Apple iTunes App Store on these measures. Krippendorff's alpha was calculated for each of the measures and reported by app category and in aggregate. The measure for interactiveness and feedback was found to have the greatest overall interrater reliability (alpha=.69). Presence of password protection (alpha=.65), whether the app was uploaded by a health care agency (alpha=.63), the number of consumer ratings (alpha=.59), and several other measures had moderate interrater reliability (alphas>.5). There was the least agreement over whether apps had errors or performance issues (alpha=.15), stated advertising policies (alpha=.16), and were easy to use (alpha=.18). There were substantial differences in the interrater reliabilities of a number of measures when they were applied to depression versus smoking apps. We found wide variation in the interrater reliability of measures used to evaluate apps, and some measures are more robust across categories of apps than others. The measures with the highest degree of interrater reliability tended to be those that involved the least rater discretion. Clinical quality measures such as effectiveness, ease of use, and performance had relatively poor interrater reliability. Subsequent research is needed to determine consistent means for evaluating the performance of apps. Patients and clinicians should consider conducting their own assessments of apps, in conjunction with

  16. Audio App Brings a Better Nights Sleep

    Science.gov (United States)

    2015-01-01

    Neuroscientist Seth Horowitz was part of a NASA-funded team at State University of New York Stony Brook demonstrating that low-amplitude vestibular stimulation could induce sleep. After recognizing the same stimulation could be applied through sound, Horowitz founded Sleep Genius, located in Park City, Utah, and released a mobile app of the same name that helps people to get a more restful sleep.

  17. EpApp: Development and evaluation of a smartphone/tablet app for adolescents with epilepsy.

    Science.gov (United States)

    Le Marne, Fleur A; Butler, Sharlene; Beavis, Erin; Gill, Deepak; Bye, Ann M E

    2018-04-01

    The study aimed to comprehensively evaluate a mobile application (EpApp), designed with stakeholder input, to educate and facilitate management of adolescents with epilepsy. A prospective cohort of adolescents with epilepsy (13-19 years) and their parent/carer participated between June 2015 and December 2016. Primary outcome measure was knowledge acquisition. Secondary outcomes were psychosocial variables (attitude towards illness and seizure self-efficacy) and clinical parameters (medication adherence, seizure burden). Functionality, design, content and app utility were appraised via survey and open-ended questions. 51 adolescents completed baseline surveys (mean age 14.49 years), 36 follow-up surveys. Both self and general epilepsy knowledge increased following intervention (p ≤ 0.005). Significantly fewer medication reminders were required during intervention (M = 2.93, p = .002) and follow-up (M = 3.54, p = .030) compared to baseline (M = 6.64). Measures of app design, content, functionality and utility were very favourable. There was no significant improvement in seizure burden, or psychosocial parameters. Educational page-visits reflected interests and concerns. This study demonstrates that EpApp increases knowledge and is engaging. The app is available free, internationally via Android/Apple platforms. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. No app for that? Make it yourself!

    CERN Multimedia

    CERN Bulletin

    2012-01-01

    Are you passionate about science? Do you like communicating that passion to the general public? Then come along to the very first CERN Summer Student Webfest kicking off on Friday 3 August! The Webfest is a grassroots initiative by the summer students, seeking to spark new ideas that could innovate the future of web-based education about CERN, the LHC and particle physics.   The CERN Summer Student Webfest is a weekend of online web-based creativity modelled on the gatherings (sometimes called hackfests or hackathons) that energize many open source communities. You can work with like-minded students and CERN staff to design and build demos of the web apps you would like to see online. Prizes will be awarded to the best apps, with a Grand Prize winner receiving a trip to the Mozilla Festival in London! Participants in the CERN Summer Student Webfest will work in teams and design neat web apps that encourage the public to learn more about science and, in particular, CERN, the LHC and particle physi...

  19. Learn ggplot2 using Shiny App

    CERN Document Server

    Moon, Keon-Woong

    2016-01-01

    This book and app is for practitioners, professionals, researchers, and students who want to learn how to make a plot within the R environment using ggplot2, step-by-step without coding. In widespread use in the statistical communities, R is a free software language and environment for statistical programming and graphics. Many users find R to have a steep learning curve but to be extremely useful once overcome. ggplot2 is an extremely popular package tailored for producing graphics within R but which requires coding and has a steep learning curve itself, and Shiny is an open source R package that provides a web framework for building web applications using R without requiring HTML, CSS, or JavaScript. This manual—"integrating" R, ggplot2, and Shiny—introduces a new Shiny app, Learn ggplot2, that allows users to make plots easily without coding. With the Learn ggplot2 Shiny app, users can make plots using ggplot2 without having to code each step, reducing typos and error messages and allowing users to bec...

  20. App Use in Psychiatric Education: A Medical Student Survey.

    Science.gov (United States)

    Lau, Cecilia; Kolli, Venkata

    2017-02-01

    The objective of the study is to understand and appraise app use by medical students during their clerkships. Following Creighton University IRB approval, a voluntary and anonymous paper-based, 15-question survey was distributed to third-year medical students. Data were analyzed using Microsoft Excel. Of 112 medical students available, 76.7% (86) participated in the survey. All participants owned a smartphone or tablet with 84.9% using Apple iOS, followed by 12.8% using Android platform. Students reported using the fewest number of apps during surgery, psychiatry, and obstetrics and gynecology clerkships. The largest number of apps were used during the internal medicine rotation (70.3%). The three most popular apps were Epocrates, UpToDate, and UWorld. The most common uses for these apps were as references during the clerkship, followed by improving knowledge, and test taking. Perceived major benefits included accessibility (96% of student respondents) and interactivity (39.5%). Common apps used during the psychiatry clerkship included UpToDate (71%), Epocrates (51%), and Medscape (43%). Despite less frequent app use during their psychiatry clerkship, 90% felt there was a utility for educational apps in psychiatric education. Consistent with the previous literature on medical students preferring educational apps, students suggest developers focus on question bank-type apps, followed by clinical support-focused and self-directed case-based learning apps for psychiatry clerkship learning. Educators should factor these modes of educational delivery into future educational app development. This survey shows a high degree of smartphone and tablet use among medical students, and they attest to mobile phone app utility in psychiatric education.

  1. Heat cost in a Swedish agrothermal plant

    International Nuclear Information System (INIS)

    Christensen, J.

    1978-01-01

    Low-grade heat is of rapidly increasing importance in Sweden and, therefore, so is the economic evaluation of such heat. The present heat cost is based on a detailed feasibility study of large-scale heated horticulture combined with electricity production from a Swedish boiling water reactor power plant. To estimate judiciously the cost of heat from a dual-purpose plant--such as a large-scale horticultural installation combined with and using low-grade waste heat from an electric power plant--is an almost classical problem: a measure of arbitrarity is unavoidable. The opportunity cost approach shown has presumably some new features. It results in an estimated cost of heat delivered from the turbine condenser heater in the power plant of 1.4 $/GJ (or 6.1 Swedish Crwn/GJ) in 1980, which is less than one-third of the cost of fuel only with conventional oil-fired heaters

  2. Effects of Swedish massage on blood pressure.

    Science.gov (United States)

    Aourell, Moa; Skoog, Martina; Carleson, J

    2005-11-01

    Swedish massage technique includes mechanically activated muscular tissue and also skin, tendons, fascias, and connected tissue, which indirectly regulates the tonus of the autonomous nervous system. This study set out to examine the effects of Swedish massage on blood pressure. Healthy males were given massage treatment at the Karolinska Hospital, Stockholm, Sweden. Treatment was over a 12-week period divided into three parts, each consisting of 4 weeks. Two treatment periods contained massage treatment either on back, neck and chest (BNC), or leg, arm and face (LAF), with an in between washout period. The first treatment period with massage decreased systolic blood pressure directly after treatment (BNC: Pmassage decreased systolic (Pmassage (Pmassage on the BNC resulted in a minor decrease in blood pressure possibly due to sympathetic inhibition. It may be suggested that massage may be tried as a complementary therapy in patients suffering from increased blood pressure due to stress.

  3. Browser App Approach: Can It Be an Answer to the Challenges in Cross-Platform App Development?

    Directory of Open Access Journals (Sweden)

    Minh Q. Huynh

    2017-02-01

    Full Text Available Aim/Purpose: As smartphones proliferate, many different platforms begin to emerge. The challenge to developers as well as IS educators and students is how to learn the skills to design and develop apps to run on cross-platforms. Background: For developers, the purpose of this paper is to describe an alternative to the complex native app development. For IS educators and students, the paper provides a feasible way to learn and develop fully functional mobile apps without technical burdens. Methodology: The methods used in the development of browser-based apps is prototyping. Our proposed approach is browser-based, supports cross-platforms, uses open-source standards, and takes advantage of “write-once-and-run-anywhere” (WORA concept. Contribution: The paper illustrates the application of the browser-based approach to create a series of browser apps without high learning curve. Findings: The results show the potentials for using browser app approach to teach as well as to create new apps. Recommendations for Practitioners\t: Our proposed browser app development approach and example would be useful to mobile app developers/IS educators and non-technical students because the source code as well as documentations in this project are available for downloading. Future Research: For further work, we discuss the use of hybrid development framework to enhance browser apps.

  4. Swedish subseabed store - phase 1 nears completion

    International Nuclear Information System (INIS)

    Daglish, James

    1987-01-01

    The paper concerns the storage of radioactive waste in the subseabed in Sweden. The wastes are low- and intermediate-level reactor wastes arising from the Swedish nuclear power programme. The repository is a cavern which has been excavated under the seabed in the Baltic Sea, about a kilometre out from shore. The specifications of the repository are given, along with the volume of the radioactive wastes to be stored in it. (UK)

  5. Swedish-Estonian energy forest research cooperation

    International Nuclear Information System (INIS)

    Ross, J.; Kirt, E.; Koppel, A.; Kull, K.; Noormets, A.; Roostalu, H.; Ross, V.; Ross, M.

    1996-01-01

    The Organization of Estonian energetic economy is aimed at cutting the usage of oil, gas and coal and increasing the local resources firewood, oil-shale and peat for fuel. The resources of low-valued firewood-brushwood, fallen deadwood etc. are available during the following 10-15 years, but in the future the cultivation of energy forest (willow) plantations will be actual. During the last 20 years the Swedish scientists have been extensively studying the willow forest selection, cultivation and use in energetics and waste water purification systems. A Swedish-Estonian energy forest research project was started in 1993 between the Swedish Agricultural University on one hand and Toravere Observatory, Institute of Zoology and Botany, Estonian Academy of Sciences and Estonian Potato Processing Association on the other hand. In spring 5 willow plantations were established with the help of Swedish colleagues and obtained from Sweden 36000 willow cuttings. The aim of the project: a) To study experimentally and by means of mathematical modelling the biogeophysical aspects of growth and productivity of willow plantations in Sweden and Estonian climatological conditions. b) To study the possibility of using the willow plantations in waste waters purification. c) To study the economical efficiency of energy forest as an energy resource under the economic and environmental conditions of Estonia. d) To study the economic efficiency of willow plantations as a raw material for the basket industry in Estonia. e) To select the most productive and least vulnerable willow clones for practical application in energy plantations. During 1993 in all five plantations detailed analysis of soil properties has been carried out. In the plantation at Toravere Observatory phytometrical measurements were carried out - the growth of plant biomass leaf and stem area, vertical distribution of dry matter content, biomass and phyto area separately for leaves and stems has been performed. Some

  6. Diversity Work in a Swedish Municipality

    OpenAIRE

    Risberg, Annette

    2013-01-01

    This paper builds on a case study of diversity work in a Swedish municipality, Malmö. It focuses on certain actors partaking in the diversity work done in the municipality that of a gender and diversity committee and its members – here called diversity ambassadors. I will describe the work of the diversity ambassadors and discuss what impact they could possibly have on the organization. Organizational efforts to change inequalities at the workplace may take different forms. The literature ...

  7. The swedish challenge; Le pari Suedois

    Energy Technology Data Exchange (ETDEWEB)

    Tregouet, R

    2006-07-01

    Sweden decided to be the first country without petroleum for 2020. The author presents the major energy policy axis implemented by the swedish government to delete the part of the produced energy by the petroleum: development of the renewable energies, research programs of the transportation sector concerning the alternative fuels for the motors, energy efficiency and development of the biomass to replace the nuclear energy. (A.L.B.)

  8. Spirometric reference equations for Swedish adults.

    Science.gov (United States)

    Brisman, Jonas; Kim, Jeong-Lim; Olin, Anna-Carin; Torén, Kjell; Bake, Björn

    2017-11-01

    New spirometric reference equations for Swedish adults are required. Three different older sets of reference equations clinically used in Sweden have various drawbacks and the recently published 'The Global Lung Function 2012 (GLI) equations' have been shown not to be adequate for Swedish normal, healthy non-smokers. We have recently concluded that a piecewise linear model presented by Lubinski and Gólczewski accurately describes the distribution of spirometric variables in a large Swedish random population sample. This piecewise linear model also offers the important advantage of implementing easily physiologically interpretable coefficients. The present study aimed at presenting piecewise linear reference equations for Swedish adults based on a random population sample of 6685 individuals aged 25-75 years. Predicted normal values by the piecewise linear reference equations and lower limit normal (LLN) were compared with the three reference equations frequently used clinically in Sweden and the GLI equations. We found predicted normal values according to the present piecewise linear reference equations close to 100% predicted normal as expected, whereas the other equations either overestimated or underestimated normal subjects. Concerning LLN, the present equations, i.e. 1·645 × RSD, showed the least deviation from the expected 5% and, e.g., the GLI equations systematically identified too few subjects below LLN. We conclude that the present piecewise linear reference equations, based on a relatively large general population sample, ought to be considered for clinical use in Sweden. Application of 1·645 × RSD below predicted value gave an acceptably accurate LLN. © 2016 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  9. PoliticAPP: Towards a Categorization of Mobile Apps in Political Communication

    Directory of Open Access Journals (Sweden)

    Pablo VÁZQUEZ SANDE

    2016-06-01

    Full Text Available This article is an analyze of all mobile apps that are available in the field of Spanish political communication, with the aim to develop a pioneering categorization of these platforms according to various criteria as promoters, aims pursued or areas of performance. It includes also a critical review from which it is concluded that these app reproduce classic communication patterns with the voters. That means that the implementation of these channels seems to have been due more to political marketing than to boost democratic participation or to introduce an horizontal outline of a new relationship between politicians and citizens.

  10. Swedish reactor safety. Barsebaeck risk assessment

    International Nuclear Information System (INIS)

    1978-01-01

    probabilistic safety analysis of the Barsebaeck reactor, a Swedish-designed Boiling Water Reactor (BWR), was done using design and reliability information from Barsebaeck and similar Swedish reactors. The methodology of the Reactor Safety (WASH-1400) was employed to the extent possible to determine the probability of major accidents at Barsebaeck. It is concluded that an accident at the Barsebaeck nuclear plant could potentially affect a large segment of the population of Sweden and of neighbouring countries. The risk consists not only of potential harm to the current population, but of possible harm to future population due to the very long lives of the radioactive materials involved. However the complexity of nuclear systems, the relatively scant data base on which to make long-term predictions of equipment reliability, and little experience in accident consequences make the uncertainty bounds of this typype of studies very broad. Thus, in the end, the decision on the question of continuation of the Swedish nuclear power program must be made outside of, but with the assistance of, the technical community. The acceptance of nuclear power as an energy source in a country becomes a decision of social acceptability and, of necessity, must be made by the social structure's appointed representatives. (E.R.)

  11. Global health education in Swedish medical schools.

    Science.gov (United States)

    Ehn, S; Agardh, A; Holmer, H; Krantz, G; Hagander, L

    2015-11-01

    Global health education is increasingly acknowledged as an opportunity for medical schools to prepare future practitioners for the broad health challenges of our time. The purpose of this study was to describe the evolution of global health education in Swedish medical schools and to assess students' perceived needs for such education. Data on global health education were collected from all medical faculties in Sweden for the years 2000-2013. In addition, 76% (439/577) of all Swedish medical students in their final semester answered a structured questionnaire. Global health education is offered at four of Sweden's seven medical schools, and most medical students have had no global health education. Medical students in their final semester consider themselves to lack knowledge and skills in areas such as the global burden of disease (51%), social determinants of health (52%), culture and health (60%), climate and health (62%), health promotion and disease prevention (66%), strategies for equal access to health care (69%) and global health care systems (72%). A significant association was found between self-assessed competence and the amount of global health education received (pcurriculum. Most Swedish medical students have had no global health education as part of their medical school curriculum. Expanded education in global health is sought after by medical students and could strengthen the professional development of future medical doctors in a wide range of topics important for practitioners in the global world of the twenty-first century. © 2015 the Nordic Societies of Public Health.

  12. Engineering stories? A narratological approach to children's book apps

    Directory of Open Access Journals (Sweden)

    Hadassah Stichnothe

    2014-01-01

    Full Text Available With the rise of smartphones and tablet pcs, children's book apps have emerged as a new type of children's media. While some of them are based on popular children's books such as Mo Willems’ Pigeon books or Beatrix Potter's Peter Rabbit, others were specifically designed as apps. This paper focuses on examining book apps under the aspects of implied user strategies and narrative structure. Using a narratological framework that also takes into account the unique characteristics of the medium, a terminology for the analysis of book apps will be sketched out. Furthermore, an exemplary analysis of iOS books apps for pre- and grade school children comes to the conclusion that, far from offering the child users room for individual creativity, a large number of apps rather train their users in following prescribed paths of reading.

  13. Mobile Phone Apps for University Students With Hazardous Alcohol Use: Study Protocol for Two Consecutive Randomized Controlled Trials.

    Science.gov (United States)

    Berman, Anne H; Gajecki, Mikael; Fredriksson, Morgan; Sinadinovic, Kristina; Andersson, Claes

    2015-12-22

    About 50% of university students overconsume alcohol, and drinking habits in later adulthood are to some extent established during higher educational studies. Several studies have demonstrated that Internet-based interventions have positive effects on drinking habits among university students. Our recent study evaluated two mobile phone apps targeting drinking choices at party occasions via personalized feedback on estimated blood alcohol concentration (eBAC) for students with hazardous drinking. No changes in drinking parameters were found over a seven-week period apart from an increase in number of drinking occasions among men for one of the apps tested. Up to 30% of the study participants drank at potentially harmful levels: higher than the national recommended number of standard drinks per week (a maximum of 9 for women and 14 for men) in Sweden. (1) To evaluate improved versions of the two mobile phone apps tested in our prior trial, in a new, 3-armed randomized controlled trial among university students with at least hazardous drinking habits according to the Alcohol Use Disorders Identifications Test (AUDIT; Study 1). (2) After 6 weeks, to target study participants showing alcohol consumption higher than the national recommended levels for standard drinks per week by offering them participation in a second, 2-armed randomized trial evaluating an additional mobile phone app with skill enhancement tasks (Study 2). (3) To follow participants at 6, 12 and 18 weeks after recruitment to Study 1 and at 6 and 12 weeks after recruitment to Study 2. Two randomized controlled trials are conducted. Study 1: Students are recruited at four Swedish universities, via direct e-mail and advertisements on Facebook and student union web sites. Those who provide informed consent, have a mobile phone, and show at least hazardous alcohol consumption according to the AUDIT (≥6 for women; ≥8 points for men) are randomized into three groups. Group 1 has access to the Swedish

  14. Web-based hybrid mobile apps: state of the practice and research opportunities

    NARCIS (Netherlands)

    Malavolta, Ivano

    2016-01-01

    This paper describes the contents of a tutorial on web-based hybrid mobile apps. Nowadays millions of mobile apps are downloaded and used all over the world. Mobile apps are distributed via different app stores like Google Play Store, the Apple App Store, the Windows Phone Store. One of the most

  15. Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: implications for human motor neuron disease.

    Science.gov (United States)

    Palmisano, Ralf; Golfi, Panagiota; Heimann, Peter; Shaw, Christopher; Troakes, Claire; Schmitt-John, Thomas; Bartsch, Jörg W

    2011-03-07

    The cause of sporadic amyotrophic lateral sclerosis (ALS) is largely unknown but hypotheses about disease mechanisms include oxidative stress, defective axonal transport, mitochondrial dysfunction and disrupted RNA processing. Whereas familial ALS is well represented by transgenic mutant SOD1 mouse models, the mouse mutant wobbler (WR) develops progressive motor neuron degeneration due to a point mutation in the Vps54 gene, and provides an animal model for sporadic ALS. VPS54 protein as a component of a protein complex is involved in vesicular Golgi trafficking; impaired vesicle trafficking might also be mechanistic in the pathogenesis of human ALS. In motor neurons of homozygous symptomatic WR mice, a massive number of endosomal vesicles significantly enlarged (up to 3 μm in diameter) were subjected to ultrastructural analysis and immunohistochemistry for the endosome-specific small GTPase protein Rab7 and for amyloid precursor protein (APP). Enlarged vesicles were neither detected in heterozygous WR nor in transgenic SOD1(G93A) mice; in WR motor neurons, numerous APP/Rab7-positive vesicles were observed which were mostly LC3-negative, suggesting they are not autophagosomes. We conclude that endosomal APP/Rab7 staining reflects impaired vesicle trafficking in WR mouse motor neurons. Based on these findings human ALS tissues were analysed for APP in enlarged vesicles and were detected in spinal cord motor neurons in six out of fourteen sporadic ALS cases. These enlarged vesicles were not detected in any of the familial ALS cases. Thus our study provides the first evidence for wobbler-like aetiologies in human ALS and suggests that the genes encoding proteins involved in vesicle trafficking should be screened for pathogenic mutations.

  16. Phosphorus flows to and from Swedish agriculture and food chain.

    Science.gov (United States)

    Linderholm, Kersti; Mattsson, Jan Erik; Tillman, Anne-Marie

    2012-12-01

    Phosphorus flows in Swedish agriculture and food chain were studied by material flow analysis. The system studied included agriculture, food consumption, related waste and wastewater from private households and municipal wastewater treatment plants. Swedish farmland had net annual phosphorus inputs of ~12, 600 metric tons (4.1 kg P ha(-1)) in 2008-2010. The total import of phosphorus in food and feed to Sweden exceed imports of phosphorus in fertilizers. Despite strict animal density regulations relating to manure phosphorus content, phosphorus is accumulating on Swedish animal farms. The total quantity of manure produced greatly exceeds imported mineral phosphorus fertilizer and almost equals total phosphorus inputs to Swedish farmland.

  17. Towards a Framework for Evaluating Mobile Mental Health Apps.

    Science.gov (United States)

    Chan, Steven; Torous, John; Hinton, Ladson; Yellowlees, Peter

    2015-12-01

    Mobile phones are ubiquitous in society and owned by a majority of psychiatric patients, including those with severe mental illness. Their versatility as a platform can extend mental health services in the areas of communication, self-monitoring, self-management, diagnosis, and treatment. However, the efficacy and reliability of publicly available applications (apps) have yet to be demonstrated. Numerous articles have noted the need for rigorous evaluation of the efficacy and clinical utility of smartphone apps, which are largely unregulated. Professional clinical organizations do not provide guidelines for evaluating mobile apps. Guidelines and frameworks are needed to evaluate medical apps. Numerous frameworks and evaluation criteria exist from the engineering and informatics literature, as well as interdisciplinary organizations in similar fields such as telemedicine and healthcare informatics. We propose criteria for both patients and providers to use in assessing not just smartphone apps, but also wearable devices and smartwatch apps for mental health. Apps can be evaluated by their usefulness, usability, and integration and infrastructure. Apps can be categorized by their usability in one or more stages of a mental health provider's workflow. Ultimately, leadership is needed to develop a framework for describing apps, and guidelines are needed for both patients and mental health providers.

  18. Apps: a new medium for non-fiction innovation

    Directory of Open Access Journals (Sweden)

    Catherine Allen

    2015-07-01

    Full Text Available Apps are now a dominant content medium: in the US people spend more time on apps than they do watching TV. Non-fiction content is being avidly consumed on mobile devices, but in a completely different way to the book model. This article explores three strands of potential that the app medium holds for non-fiction content, putting forward the case that apps have the power to further weave non-fiction into the fabric of society and life.

  19. WhatsApp in Clinical Practice: A Literature Review.

    Science.gov (United States)

    Mars, Maurice; Scott, Richard E

    2016-01-01

    Several spontaneous telemedicine services using WhatsApp Messenger have started in South Africa raising issues of confidentiality, data security and storage, record keeping and reporting. This study reviewed the literature on WhatsApp in clinical practice, to determine how it is used, and users' satisfaction. Pubmed, Scopus, Science Direct and IEE Expert databases were searched using the search term WhatsApp and Google Scholar using the terms WhatsApp Telemedicine and WhatsApp mHealth. Thirty-two papers covering 17 disciplines were relevant with the most papers, 12, from India. Seventeen papers reported the use of WhatsApp Groups within departments, 14 of which were surgery related disciplines. Groups improved communication and advice given on patient management. Confidentiality was mentioned in 19 papers and consent in five. Data security was partially addressed in 11 papers with little understanding of how data are transmitted and stored. Telemedicine services outside of departmental groups were reported in seven papers and covered emergency triage in maxillofacial, plastic, neuro and general surgery, and cardiology and telestroke. WhatsApp is seen to be a simple, cheap and effective means of communication within the clinical health sector and its use will grow. Users have paid little attention to confidentiality, consent and data security. Guidelines for using WhatsApp for telemedicine are required including downloading. WhatsApp messages to computer for integration with electronic medical records.

  20. Plausibility of Menstrual Cycle Apps Claiming to Support Conception

    Directory of Open Access Journals (Sweden)

    Alexander Freis

    2018-04-01

    Full Text Available The interval of peak fertility during the menstrual cycle is of limited duration, and the day of ovulation varies, even in women with fairly regular cycles. Therefore, menstrual cycle apps identifying the “fertile window” for women trying to conceive must be quite precise. A deviation of a few days may lead the couple to focus on less- or non-fertile days for sexual intercourse and thus may be worse than random intercourse. The aim of the present investigation was to develop a scoring system for rating available apps for determining the fertile window and secondarily pilot test 12 apps currently available in both German and English (consisting of 6 calendar-based apps: Clue Menstruations- und Zykluskalender, Flo Menstruationskalender, Maya-Mein Periodentracker, Menstruationskalender Pro, Period Tracker Deluxe, and WomanLog-Pro-Kalender; 2 calculothermal apps: Ovy and Natural Cycles; and 4 symptothermal apps: myNFP, Lady Cycle, Lily, and OvuView. The calendar-based apps were investigated by entering several series of cycles with varying lengths, whereas the symptom-based apps were examined by entering data of cycles with known temperature rise, cervical mucus pattern, and clinical ovulation. The main criteria for evaluating the cycle apps were as follows: (1 What methods/parameters were used to determine the fertile window? (2 What study results exist concerning that underlying method/parameters? (3 What study results exist concerning the app itself? (4 Was there a qualified counseling service? The calendar-based apps predicted the fertile days based on data of previous cycles. They obtained zero points in our scoring system, as they did not comply with any of the evaluated criteria. Calculothermal apps had similar deficits for predicting the most fertile days and produced suboptimal results (Ovy 3/30 points and Natural Cycles 2/30 points. The symptothermal apps determined the fertile days based on parameters of the current cycle: Lady Cycle

  1. Plausibility of Menstrual Cycle Apps Claiming to Support Conception.

    Science.gov (United States)

    Freis, Alexander; Freundl-Schütt, Tanja; Wallwiener, Lisa-Maria; Baur, Sigfried; Strowitzki, Thomas; Freundl, Günter; Frank-Herrmann, Petra

    2018-01-01

    The interval of peak fertility during the menstrual cycle is of limited duration, and the day of ovulation varies, even in women with fairly regular cycles. Therefore, menstrual cycle apps identifying the "fertile window" for women trying to conceive must be quite precise. A deviation of a few days may lead the couple to focus on less- or non-fertile days for sexual intercourse and thus may be worse than random intercourse. The aim of the present investigation was to develop a scoring system for rating available apps for determining the fertile window and secondarily pilot test 12 apps currently available in both German and English (consisting of 6 calendar-based apps: Clue Menstruations- und Zykluskalender, Flo Menstruationskalender, Maya-Mein Periodentracker, Menstruationskalender Pro, Period Tracker Deluxe, and WomanLog-Pro-Kalender; 2 calculothermal apps: Ovy and Natural Cycles; and 4 symptothermal apps: myNFP, Lady Cycle, Lily, and OvuView). The calendar-based apps were investigated by entering several series of cycles with varying lengths, whereas the symptom-based apps were examined by entering data of cycles with known temperature rise, cervical mucus pattern, and clinical ovulation. The main criteria for evaluating the cycle apps were as follows: (1) What methods/parameters were used to determine the fertile window? (2) What study results exist concerning that underlying method/parameters? (3) What study results exist concerning the app itself? (4) Was there a qualified counseling service? The calendar-based apps predicted the fertile days based on data of previous cycles. They obtained zero points in our scoring system, as they did not comply with any of the evaluated criteria. Calculothermal apps had similar deficits for predicting the most fertile days and produced suboptimal results (Ovy 3/30 points and Natural Cycles 2/30 points). The symptothermal apps determined the fertile days based on parameters of the current cycle: Lady Cycle scored 20

  2. Resolving the Innovation Diffusion Paradox in Mobile App Stores

    DEFF Research Database (Denmark)

    Xiong, Bingqing; Tan, Chee-Wee; Wang, Weiquan

    2017-01-01

    to the abundance of apps and multitudinous promotional information. To this end, this study proposes branding as a strategy to tackle the innovation diffusion paradox. Specifically, we construct a research model that posits consumers’ brand awareness as an antecedent affecting their brand association and quality...... which, when taken together, affect their knowledge of affiliated apps and download intentions in mobile app stores. Based on data gathered via a preliminary online survey administered on consumers belonging to one of the largest mobile app stores in China, we attest to the impact of branding...

  3. Subgrouping the users of a specialized app for eating disorders.

    Science.gov (United States)

    Sadeh-Sharvit, Shiri; Kim, Jane Paik; Darcy, Alison M; Neri, Eric; Vierhile, Molly; Robinson, Athena; Tregarthen, Jenna; Lock, James D

    2018-02-16

    Although mobile technologies for eating disorders (EDs) are burgeoning, there is limited data about the clinical characteristics of individuals using specialized smartphone applications (apps) without accompanying traditional forms of treatment. This study evaluated whether the users of an ED app cluster in clinically meaningful groups. Participants were 1,280 app users (91.3% female; mean age 27) who reported not being in a weekly treatment for their ED. A hierarchical cluster analysis distinguished five groups of participants, all approximating DSM-5 ED categories. One cluster comprised of non-female, ethnically diverse users with Bulimia Nervosa features. Findings suggest that app users resemble known patient classifications.

  4. A Novel Approach for Designing Mobile Native Apps

    Directory of Open Access Journals (Sweden)

    Sasmita Pani

    2017-01-01

    Full Text Available Mobile devices are differed from desktop based systems in terms of particular execution environment, constrained resources, and high mobility requirement. To overcome these shortcomings, various agile based methodologies are developed for native mobile applications such as Mobile-D, Scrum etc. These agile techniques are based on various phases and these phases begin from exploring, initializing and implementing the mobile apps. But these techniques are not focusing on elaborating design model for mobile native apps. The aim of the paper is to provide a layered approach or layered model for design of mobile native apps which can be used as a framework for developing mobile native apps. Any mobile native app developer can use this sequential approach or design model for design and development of mobile native apps. This design model gives a standard or framework, based on which generic native mobile apps can be designed and developed. This paper also shows an empirical analysis among the web app design models with the proposed design model for mobile native app development.

  5. Evaluation of a medicines list iPhone app.

    Science.gov (United States)

    Wickham, Brendon; Holbrook, Rachel; Dinh, Kathryn

    2013-01-01

    A medicines list iPhone app, based on an existing paper product, was developed by NPS MedicineWise for consumers. Since its launch in June 2011 the app has been downloaded over 19,000 times. With plans to expand its development and increase its use, it was critical to discover how the app is used and how useful it is. A total of 61 study participants used the app for five days and then participated in online focus groups. While most people have a system for managing their medicines, these systems vary in their effectiveness. The biggest problem with managing medicines is when medicine doses are forgotten or taken late. Usability problems with the app were revealed. While the app was easy to install, it was time consuming and difficult to input medicine information. The majority of people did not enter information in all fields. While the app was deemed useful and will continue to be used by the majority of participants, not all participants were aware of the existing functions or the capabilities of the functions. Use was primarily for self-management. The majority of participants were comfortable sharing the information in the app (via the phone) with a health professional. Roughly half wanted to upload their information to the PCEHR. Recommendations were made and incorporated into design decisions for an updated version of the app (which includes potential linking to the PCEHR), and a multi-platform release (web, iOS, Android, Windows Mobile).

  6. Quality of Smartphone Apps Related to Alcohol Use Disorder.

    Science.gov (United States)

    Penzenstadler, Louise; Chatton, Anne; Van Singer, Mathias; Khazaal, Yasser

    2016-01-01

    Apps for smartphones are opening an important range of opportunities for improving the care of people with alcohol use disorders (AUDs). This study aimed to evaluate the quality of English language apps for AUDs and to compare paid and free apps. The keywords 'alcohol', 'alcohol addiction', 'alcohol help' and 'stop drinking' were entered into the iTunes Store search engine. Apps were evaluated using a standardized assessment designed to rate the quality of apps in terms of accountability, interactivity, self-help score and evidence-based content. The Brief DISCERN score and the criteria of the 'Health on the Net' label were also used as content quality indicators. Of the 137 unique apps identified, 52 met the inclusion criteria. Overall, the content quality and self-help scores of these AUD apps were poor. The main quality indicators were not linked to payment status. Multiple linear regressions showed that the Brief DISCERN score significantly predicted content quality. Poor content quality and self-help scores of AUD smartphone apps underline the gap between their potential promises and the overall quality of available products in stores. The quality indicators used in the present study may be used for further app developments. © 2016 S. Karger AG, Basel.

  7. ‘Gamification’ for Health Behaviour Change in Smartphone Apps

    Directory of Open Access Journals (Sweden)

    Elizabeth Ann Edwards

    2015-09-01

    Full Text Available Background: Gamification techniques are showing promise in promoting healthy behaviours and delivering health promotion advice, however, their use in Mobile-Health is relatively new. Gamification involves using ‘gaming’ elements such as badges, leader boards, health-related challenges, rewards, ability to ‘level up’ and use of avatars to motivate and engage people to change health behavior. Gamification techniques may also overlap with validated health behaviour change techniques (BCTs, however, few apps appear to apply the techniques systematically or to define the BCTs they include. Aim: We aimed a to assess the number apps that incorporate gamification to modify health behaviors, b to examine the BCT repertoire and combinations used in these apps c to consider associations with user satisfaction. Methods: English-language health apps that contain gamification techniques were identified through a systematic search of the official Apple and Google Play store and the NHS health apps library. Top rated free and paid Medical, Health & Wellness, Health & Fitness apps as defined by Apple and Google Play stores were searched. Apps were coded for BCTs according to the Michie et al. taxonomy. The taxonomy comprises 16 categories and 93 individual BCTs. BCT coding was conducted by two trained researchers (EE, JL who scored independently and then cross-checked for discrepancies. BCT numbers, user ratings and app pricing were compared. We explored the association between number of BCTs per app, user and NHS libraries’ ratings and price. We also investigated, which of the 16 BCT categories and the individual 93 BCTs and their combinations were most commonly used. Results: 1,680 Medical, Health & Wellness or Health & Fitness Apps were reviewed and seventy containing gamification techniques were identified. The mean number of BCTs used was 12.5 (range 1-24. There was no correlation between number of BCTs, customer ratings, NHS library app rating or

  8. Mutants of alfalfa mosaic virus

    International Nuclear Information System (INIS)

    Roosien, J.

    1983-01-01

    In this thesis the isolation and characterization of a number of mutants of alfalfa mosaic virus, a plant virus with a coat protein dependent genome, is described. Thermo-sensitive (ts) mutants were selected since, at least theoretically, ts mutations can be present in all virus coded functions. It was found that a high percentage of spontaneous mutants, isolated because of their aberrant symptoms, were ts. The majority of these isolates could grow at the non-permissive temperature in the presence of a single wild type (wt) component. To increase the mutation rate virus preparations were treated with several mutagens. After nitrous acid treatment or irradiation with ultraviolet light, an increase in the level of mutations was observed. UV irradiation was preferred since it did not require large amounts of purified viral components. During the preliminary characterization of potential ts mutants the author also obtained one structural and several symptom mutants which were analysed further (chapter 7, 8 and 9). The properties of the ts mutants are described in chapter 3-7. (Auth.)

  9. The Anatomy of Virtual Manipulative Apps: Using Grounded Theory to Conceptualize and Evaluate Educational Apps that Contain Virtual Manipulatives

    OpenAIRE

    Boyer-Thurgood, Jennifer M.

    2017-01-01

    This exploratory qualitative study used grounded theory to investigate the anatomy of educational apps that contain virtual manipulatives. For this study 100 virtual manipulatives within educational apps designed for the iPad were observed by the researcher in order to expand the explanations of and build theory about virtual manipulatives within apps. Affordance theory was used to frame all six phases of the study in which the researcher identified virtual manipulatives situated within educa...

  10. The App Map: A Tool for Systematic Evaluation of Apps for Early Literacy Learning

    Science.gov (United States)

    Israelson, Madeleine Heins

    2015-01-01

    As portable devices become increasingly available in elementary classrooms teachers are expected to use these new technologies to engage students in both traditional print-based literacy learning and digital literacies practices, such as multimodal composing. Teachers face the daunting task of integrating apps into their current research-based…

  11. Leakiness and Creepiness in App Space: User Perceptions of Privacy and Mobile App Use

    DEFF Research Database (Denmark)

    Shklovski, Irina; Mainwaring, Scott; Skúladóttir, Halla Hrund

    2014-01-01

    confronted with app behaviors and their reactions assessed. Users felt their personal space had been violated in “creepy” ways. Using Altman’s notions of personal space and territoriality, and Nissenbaum’s theory of contextual integrity, we account for these emotional reactions and sug- gest that they point...

  12. 3rd MeTrApp Conference

    CERN Document Server

    Lovasz, Erwin-Christian; Hüsing, Mathias

    2015-01-01

    This volume deals with topics such as mechanism and machine design, biomechanics and medical engineering, gears, mechanical transmissions, mechatronics, computational and experimental methods, dynamics of mechanisms and machines, micromechanisms and microactuators, and history of mechanisms and transmissions. Following MeTrApp 2011 and 2013, held under the auspices of the IFToMM, these proceedings of the 3rd Conference on Mechanisms, Transmissions and Applications offer a platform for original research presentations for researchers, scientists, industry experts and students in the fields of mechanisms and transmissions with special emphasis on industrial applications in order to stimulate the exchange of new and innovative ideas.

  13. Evaluating the Dietary and Nutritional Apps in the Google Play Store.

    Science.gov (United States)

    Schumer, Harleigh; Amadi, Chioma; Joshi, Ashish

    2018-01-01

    The objective of this study was to evaluate the features of diet and nutrition apps available in the Google Play Store. A search was conducted in August 2017 using the Google Play Store database to identify apps related to diet and nutrition. Terms entered into the app search engine included 'diet apps' and 'nutrition apps'. The first 50 apps resulting from each search term was assessed. Duplicates were removed, and a comparative analysis was performed on the remaining diet and nutrition apps. A total of 86 diet and nutrition apps were identified. One hundred percent (n = 86) of the apps retrieved were freely available. More than half of the apps were applicable to a target user group of all ages (94%, n = 81). Stratified analysis across unique diet and nutrition apps (total, n = 72) showed a higher average rating for the diet apps (4.4) in comparison to that for the nutrition apps (4.3). Diet apps were more likely to be recently updated than the nutrition apps (72% vs. 66%), and diet apps were more likely to feature app purchase than nutrition apps (36% vs. 19%). The average rating was slightly higher for diet apps not featuring in-app purchases, but ratings were similar for the nutrition apps. A centralized resource is needed that can provide information on health-related apps to allow for systematic evaluation of their effectiveness. Further research needs to examine improved methods of designing app-store platforms and presenting the available apps to properly guide users in app selection.

  14. Smartphone Apps for Measuring Human Health and Climate Change Co-Benefits: A Comparison and Quality Rating of Available Apps.

    Science.gov (United States)

    Sullivan, Rachel K; Marsh, Samantha; Halvarsson, Jakob; Holdsworth, Michelle; Waterlander, Wilma; Poelman, Maartje P; Salmond, Jennifer Ann; Christian, Hayley; Koh, Lenny Sc; Cade, Janet E; Spence, John C; Woodward, Alistair; Maddison, Ralph

    2016-12-19

    Climate change and the burden of noncommunicable diseases are major global challenges. Opportunities exist to investigate health and climate change co-benefits through a shift from motorized to active transport (walking and cycling) and a shift in dietary patterns away from a globalized diet to reduced consumption of meat and energy dense foods. Given the ubiquitous use and proliferation of smartphone apps, an opportunity exists to use this technology to capture individual travel and dietary behavior and the associated impact on the environment and health. The objective of the study is to identify, describe the features, and rate the quality of existing smartphone apps which capture personal travel and dietary behavior and simultaneously estimate the carbon cost and potential health consequences of these actions. The Google Play and Apple App Stores were searched between October 19 and November 6, 2015, and a secondary Google search using the apps filter was conducted between August 8 and September 18, 2016. Eligible apps were required to estimate the carbon cost of personal behaviors with the potential to include features to maximize health outcomes. The quality of included apps was assessed by 2 researchers using the Mobile Application Rating Scale (MARS). Out of 7213 results, 40 apps were identified and rated. Multiple travel-related apps were identified, however no apps solely focused on the carbon impact or health consequences of dietary behavior. None of the rated apps provided sufficient information on the health consequences of travel and dietary behavior. Some apps included features to maximize participant engagement and encourage behavior change towards reduced greenhouse gas emissions. Most apps were rated as acceptable quality as determined by the MARS; 1 was of poor quality and 10 apps were of good quality. Interrater reliability of the 2 evaluators was excellent (ICC=0.94, 95% CI 0.87-0.97). Existing apps capturing travel and dietary behavior and the

  15. Public health guidelines for physical activity: is there an app for that? A review of android and apple app stores.

    Science.gov (United States)

    Knight, Emily; Stuckey, Melanie I; Prapavessis, Harry; Petrella, Robert J

    2015-05-21

    Physical activity participation is an important behavior for modifying lifestyle-related disease risk. Mobile health apps for chronic disease management and prevention are being developed at a rapid rate. However, it is unclear whether these apps are evidence-based. Current public health recommendations for physical activity participation for adults highlight the importance of engaging in 150 minutes weekly of purposeful exercise, and muscle strengthening activities on at least 2 days of the week. The aims of the present review were to (1) identify available evidence-based physical activity apps, and (2) identify technological features that could be leveraged to improve health outcomes. iTunes and Google Play mobile app stores were searched using keyword and category searching during a single day (February 18, 2014) for physical activity apps available in English. The description pages of eligible apps were reviewed by 4 independent reviewers for evidence-based content, technological, and descriptive features. An a priori subset of apps was downloaded for further review (n=6 affiliated with a non-commercial agency; n=10 top rated; n=10 random selection), and developers were contacted for information regarding evidence-informed content. The initial search yielded 2400 apps, of which 379 apps (n=206 iTunes; n=173 Google Play) were eligible. Primary results demonstrated no apps (n=0) adhering to evidence-based guidelines for aerobic physical activity, and 7 out of 379 implementing evidence-based guidelines for resistance training physical activity. Technological features of apps included social networking (n=207), pairing with a peripheral health device (n=61), and measuring additional health parameters (n=139). Secondary results revealed 1 app that referenced physical activity guidelines (150 minutes/weekly of exercise), and demonstrated that apps were based on various physical activity reports (n=4) or personal expertise (n=2). The present study demonstrated a

  16. Qualitative evaluation of mobile cancer apps with particular attention to the target group, content, and advertising.

    Science.gov (United States)

    Böhme, Cathleen; von Osthoff, Marc Baron; Frey, Katrin; Hübner, Jutta

    2018-01-01

    Medical apps are gaining importance rapidly. Also in the field of cancer care, apps are offered. Yet, so far little is known with respect to their quality. In a pilot phase we developed a rating tool based on formal and content-related criteria for the assessment of cancer apps. We used this instrument on cancer apps available in the App Store (iOS) concerning breast, prostate and colorectal cancer. The results were stratified according to target group, content and advertising. We assessed 41 mobile cancer apps. Six apps (14.63%) scored very high, fifteen apps (36.59%) high, seventeen apps (41.46%) were deficient, and three apps (7.32%) were insufficient. The largest group of apps represents those apps with the "deficient" rating. The very good to good apps had reliable sources, a concrete intent/ purpose in their app description, and a strict distinction of scientific content and advertisement. Apps with the predicates "deficient" or "insufficient" had particularly poor ratings, e.g. in the subscales "information on sources" and "data protection". Almost half of the tested apps were deficient or insufficient. In order to improve safety of patients using apps, some regulation seems mandatory. Putting apps under the legislation for medical products might be one way to better regulate and control quality. Second, efforts should focus on the development of checklists that make it easier for patients to search for suitable cancer apps.

  17. Mobile Apps for Weight Management: A Scoping Review.

    Science.gov (United States)

    Rivera, Jordan; McPherson, Amy; Hamilton, Jill; Birken, Catherine; Coons, Michael; Iyer, Sindoora; Agarwal, Arnav; Lalloo, Chitra; Stinson, Jennifer

    2016-07-26

    Obesity remains a major public health concern. Mobile apps for weight loss/management are found to be effective for improving health outcomes in adults and adolescents, and are pursued as a cost-effective and scalable intervention for combating overweight and obesity. In recent years, the commercial market for 'weight loss apps' has expanded at rapid pace, yet little is known regarding the evidence-based quality of these tools for weight control. To characterize the inclusion of evidence-based strategies, health care expert involvement, and scientific evaluation of commercial mobile apps for weight loss/management. An electronic search was conducted between July 2014 and July 2015 of the official app stores for four major mobile operating systems. Three raters independently identified apps with a stated goal of weight loss/management, as well as weight loss/management apps targeted to pediatric users. All discrepancies regarding selection were resolved through discussion with a fourth rater. Metadata from all included apps were abstracted into a standard assessment criteria form and the evidence-based strategies, health care expert involvement, and scientific evaluation of included apps was assessed. Evidence-based strategies included: self-monitoring, goal-setting, physical activity support, healthy eating support, weight and/or health assessment, personalized feedback, motivational strategies, and social support. A total of 393 apps were included in this review. Self-monitoring was most common (139/393, 35.3%), followed by physical activity support (108/393, 27.5%), weight assessment (100/393, 25.4%), healthy eating support (91/393, 23.2%), goal-setting (84/393, 21.4%), motivational strategies (28/393, 7.1%), social support (21/393, 5.3%), and personalized feedback (7/393, 1.8%). Of apps, 0.8% (3/393) underwent scientific evaluation and 0.3% (1/393) reported health care expert involvement. No apps were comprehensive in the assessment criteria, with the majority

  18. Interaction Modes for Emergency Mobile Apps

    Directory of Open Access Journals (Sweden)

    Claudia Nass

    2018-01-01

    Full Text Available While seemingly irrational behaviors such as panicking or displaying antisocial behavior are the responses to emergency situations the media and movies lead us to believe, several studies show that people rather react based on decision-making such as acting altruistically and protectively. However, what can we really expect from people in a crowd in terms of participation in an emergency response system? In this paper, we present a mobile application called the RESCUER App, which allows civilians to participate in the emergency response process by providing information about the emergency to a command center and to receive instructions from this command center. We developed a human reaction model for emergencies to better understand the human–computer interaction capabilities of people in an emergency situation. Based on this model, we defined three different interaction modes: one-click interaction, guided interaction, and chat interaction. These interaction modes were implemented in an interactive prototype and evaluated in an experiment in which high cognitive load was induced to simulate a stress situation, similar to the stress experienced in an emergency. The experiment results showed that the three predefined interaction modes enabled people to interact with the RESCUER App even though they were in a stress situation.

  19. Medical applications: a database and characterization of apps in Apple iOS and Android platforms.

    Science.gov (United States)

    Seabrook, Heather J; Stromer, Julie N; Shevkenek, Cole; Bharwani, Aleem; de Grood, Jill; Ghali, William A

    2014-08-27

    Medical applications (apps) for smart phones and tablet computers are growing in number and are commonly used in healthcare. In this context, there is a need for a diverse community of app users, medical researchers, and app developers to better understand the app landscape. In mid-2012, we undertook an environmental scan and classification of the medical app landscape in the two dominant platforms by searching the medical category of the Apple iTunes and Google Play app download sites. We identified target audiences, functions, costs and content themes using app descriptions and captured these data in a database. We only included apps released or updated between October 1, 2011 and May 31, 2012, with a primary "medical" app store categorization, in English, that contained health or medical content. Our sample of Android apps was limited to the most popular apps in the medical category. Our final sample of Apple iOS (n = 4561) and Android (n = 293) apps illustrate a diverse medical app landscape. The proportion of Apple iOS apps for the public (35%) and for physicians (36%) is similar. Few Apple iOS apps specifically target nurses (3%). Within the Android apps, those targeting the public dominated in our sample (51%). The distribution of app functions is similar in both platforms with reference being the most common function. Most app functions and content themes vary considerably by target audience. Social media apps are more common for patients and the public, while conference apps target physicians. We characterized existing medical apps and illustrated their diversity in terms of target audience, main functions, cost and healthcare topic. The resulting app database is a resource for app users, app developers and health informatics researchers.

  20. Swedish Chemists and Discovery of the Elements

    Science.gov (United States)

    Thomsen, Volker

    1996-10-01

    All of the elements not already known from antiquity were discovered in Europe and North America. So which country ranks number one on the discovery list? The question occurred to me while leafing through reference 1 in search of thermodynamic data on silicon. Never having seen such a tabulation, I wondered if it might prove useful in teaching. The question has a sports-related flavor that will appeal to many students. Personally, I picked England or Germany for #1. The actual result is surprising. The ranking considering only up to atomic number 103 is as follows: Note: Where two or more independent discoveries have been made, each country is credited. In the "others" category Austria and Denmark each has two discoveries. The remaining countries, with one each, are Finland, Italy, Mexico, Poland, Romania, Russia, and Spain. The high place for the USA is primarily due to the work done at Berkeley and Los Alamos on the transuranics. Without these discoveries, the US would have tied with Switzerland at three elements. Perhaps the most interesting aspect of this tabulation is that Swedish chemists have discovered the most elements. Four chemists alone account for twelve of the 20 discoveries: Baron Jöns Jakob Berzelius (1779-1848) is credited with four elements. His pupil, friend, and assistant, Carl Gustav Mosander (1797-1858) discovered three. P. T. Cleve also found three elements and Karl Wilhelm Scheele (1742-1786) discovered two. Biographical research on the Swedish chemists is a suitable assignment at the introductory level. Reasons for the predominance of Swedish chemists presents a challenging student research topic in the history of chemistry. Another interesting question at the introductory level is, transuranics aside, who discovered the most elements? At the more advanced level the question becomes, why? Literature Cited: 1. Emsley, J. The Elements; Clarendon: Oxford, 1989.

  1. Preschool Education and Day Care for Swedish Children.

    Science.gov (United States)

    Mueller, Jeanne

    A comprehensive study of the types of care provided for Swedish children is presented. The point is made that the three major frameworks which support the Swedish philosophy of early childhood education are those of Arnold Gesell, Jean Piaget, and Erik H. Erikson. From all three sources, preschool teachers learn the concept of epigenesis, the…

  2. The nuclear waste issue in Swedish mass media

    International Nuclear Information System (INIS)

    Hedberg, P.

    1991-04-01

    This is an investigation of the representation given in the Swedish mass media of questions concerning the nuclear waste. The investigation covers the period from 1979 to 1989 of 8 newspapers of different political colours and the Swedish radio and television. (KAE)

  3. Parental Expectations of the Swedish Municipal School of Arts

    Science.gov (United States)

    Lilliedahl, Jonathan; Georgii-Hemming, Eva

    2009-01-01

    This article draws on a study designed to analyse parental expectations of the Swedish municipal school of arts (hereafter MSA) (in Swedish: kommunal musik- och kulturskola). The study is based on in-depth interviews conducted and informed by grounded theory. Although parental expectations are scarcely uniform, the study reveals a hope that the…

  4. Irradiated fuel storage and transport: A Swedish perspective

    International Nuclear Information System (INIS)

    Mennerdahl, D.

    2001-01-01

    This paper gives the views of the author and may not correspond to the views of the Swedish industry or the licensing authority. The views are based on experience from consultation to the Swedish licensing authority and from participation in international cooperation, in particular in the OECD/NEA NSC Working Group on Burnup Credit. (author)

  5. Valuable features in mobile health apps for patients and consumers: content analysis of apps and user ratings.

    Science.gov (United States)

    Mendiola, Martin F; Kalnicki, Miriam; Lindenauer, Sarah

    2015-05-13

    The explosion of mobile phones with app capabilities coupled with increased expectations of the patient-consumers' role in managing their care presents a unique opportunity to use mobile health (mHealth) apps. The aim of this paper is to identify the features and characteristics most-valued by patient-consumers ("users") that contribute positively to the rating of an app. A collection of 234 apps associated with reputable health organizations found in the medical, health, and fitness categories of the Apple iTunes store and Google Play marketplace was assessed manually for the presence of 12 app features and characteristics. Regression analysis was used to determine which, if any, contributed positively to a user's rating of the app. Analysis of these 12 features explained 9.3% (R(2)=.093 n=234, Prating, with only 5 reaching statistical significance. Of the 5 reaching statistical significance, plan or orders, export of data, usability, and cost contributed positively to a user's rating, while the tracker feature detracted from it. These findings suggest that users appreciate features that save time over current methods and identify an app as valuable when it is simple and intuitive to use, provides specific instructions to better manage a condition, and shares data with designated individuals. Although tracking is a core function of most health apps, this feature may detract from a user's experience when not executed properly. Further investigation into mHealth app features is worthwhile given the inability of the most common features to explain a large portion of an app's rating. In the future, studies should focus on one category in the app store, specific diseases, or desired behavior change, and methods should include measuring the quality of each feature, both through manual assessment and evaluation of user reviews. Additional investigations into understanding the impact of synergistic features, incentives, social media, and gamification are also warranted to

  6. Apps seeking theories: results of a study on the use of health behavior change theories in cancer survivorship mobile apps.

    Science.gov (United States)

    Vollmer Dahlke, Deborah; Fair, Kayla; Hong, Y Alicia; Beaudoin, Christopher E; Pulczinski, Jairus; Ory, Marcia G

    2015-03-27

    Thousands of mobile health apps are now available for use on mobile phones for a variety of uses and conditions, including cancer survivorship. Many of these apps appear to deliver health behavior interventions but may fail to consider design considerations based in human computer interface and health behavior change theories. This study is designed to assess the presence of and manner in which health behavior change and health communication theories are applied in mobile phone cancer survivorship apps. The research team selected a set of criteria-based health apps for mobile phones and assessed each app using qualitative coding methods to assess the application of health behavior change and communication theories. Each app was assessed using a coding derived from the taxonomy of 26 health behavior change techniques by Abraham and Michie with a few important changes based on the characteristics of mHealth apps that are specific to information processing and human computer interaction such as control theory and feedback systems. A total of 68 mobile phone apps and games built on the iOS and Android platforms were coded, with 65 being unique. Using a Cohen's kappa analysis statistic, the inter-rater reliability for the iOS apps was 86.1 (PMobile apps are rapidly emerging as a way to deliver health behavior change interventions that can be tailored or personalized for individuals. As these apps and games continue to evolve and include interactive and adaptive sensors and other forms of dynamic feedback, their content and interventional elements need to be grounded in human computer interface design and health behavior and communication theory and practice.

  7. Smartphone Technology and Apps: Rapidly Changing Health Promotion

    Science.gov (United States)

    Kratzke, Cynthia; Cox, Carolyn

    2012-01-01

    Despite the increased availability of smartphones and health applications (apps), little is known about smartphone technology and apps for implementation in health promotion practice. Smartphones are mobile devices with capabilities for e-mail, text messaging, video viewing, and wireless Internet access. It is essential for health promotion…

  8. The Mersey Burns App: evolving a model of validation.

    Science.gov (United States)

    Barnes, Jamie; Duffy, Annie; Hamnett, Nathan; McPhail, Jane; Seaton, Chris; Shokrollahi, Kayvan; James, M Ian; McArthur, Paul; Pritchard Jones, Rowan

    2015-08-01

    'Mersey Burns App' is a smartphone/tablet application that aids in the assessment of total burn surface area (TBSA) and calculation of fluid resuscitation protocols in burns. This paper presents two studies assessing the speed and accuracy of calculations using Mersey Burns (App) in comparison with a Lund and Browder chart (paper) when a burn is assessed by medical students and clinicians. The first study compared the speed and accuracy of TBSA and resuscitation calculation for a photograph of a burn with App and paper using burns and plastics and emergency medicine trainees and consultants. Developing on some of the feedback and results of that study, a second study was then carried out using burns-naive medical students assessing a fully simulated burn with both modalities. Preference and ease of use of each modality were assessed anonymously. The clinician study showed a lower variance in TBSA and fluid calculations using the App (pcalculations was faster and calculations were more likely to be correct with the App (pcalculation, overall use and shading (pBurns App can facilitate quicker and more accurate calculations than Lund and Browder charts. Students also preferred the App. This suggests a useful role for the App in the care of patients with burns by inexperienced staff. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  9. Examining Preservice Teachers' Criteria for Evaluating Educational Mobile Apps

    Science.gov (United States)

    Baran, Evrim; Uygun, Erdem; Altan, Tugba

    2017-01-01

    Recent interest in integrating mobile apps into teaching will continue growing. There remains, however, a pressing need to develop methods and resources to support and educate preservice teachers about the use of these technologies. This case study aimed to examine preservice teachers' criteria for evaluating educational mobile apps. Nineteen…

  10. Validation of a Tool Evaluating Educational Apps for Smart Education

    Science.gov (United States)

    Lee, Jeong-Sook; Kim, Sung-Wan

    2015-01-01

    The purpose of this study is to develop and validate an evaluation tool of educational apps for smart education. Based on literature reviews, a potential model for evaluating educational apps was suggested. An evaluation tool consisting of 57 survey items was delivered to 156 students in middle and high schools. An exploratory factor analysis was…

  11. Designing and Creating an Educational App Rubric for Preschool Teachers

    Science.gov (United States)

    Papadakis, Stamatios; Kalogiannakis, Michail; Zaranis, Nicholas

    2017-01-01

    International studies indicate that the use of smart mobile devices and their accompanying educational applications (apps) can revolutionize young children's learning experiences. Although there is a vast array of educational apps for preschoolers, they are not actually educational in their majority. In this context, it is important for preschool…

  12. A Comprehensive Evaluation Rubric for Assessing Instructional Apps

    Science.gov (United States)

    Lee, Cheng-Yuan; Cherner, Todd Sloan

    2015-01-01

    There is a pressing need for an evaluation rubric that examines all aspects of educational apps designed for instructional purposes. In past decades, many rubrics have been developed for evaluating educational computer-based programs; however, rubrics designed for evaluating the instructional implications of educational apps are scarce. When an…

  13. Citrix XenApp 7.5 desktop virtualization solutions

    CERN Document Server

    Paul, Andy

    2014-01-01

    If you are a Citrix® engineer, a virtualization consultant, or an IT project manager with prior experience of using Citrix XenApp® and related technologies for desktop virtualization and want to further explore the power of XenApp® for flawless desktop virtualization, then this book is for you.

  14. Mobile Distance Learning with Smartphones and Apps in Higher Education

    Science.gov (United States)

    Vázquez-Cano, Esteban

    2014-01-01

    In this paper, the results of researcher' ongoing activities regarding the use of smartphones and a specific subject-app used at the Spanish National University of Distance Education (UNED) have been reported. The purpose of this trial is to assess the app's didactic use and potential to enhance student learning in university subjects in…

  15. iPhone apps for smoking cessation: a content analysis.

    Science.gov (United States)

    Abroms, Lorien C; Padmanabhan, Nalini; Thaweethai, Lalida; Phillips, Todd

    2011-03-01

    With the proliferation of smartphones such as the iPhone, mobile phones are being used in novel ways to promote smoking cessation. This study set out to examine the content of the 47 iPhone applications (apps) for smoking cessation that were distributed through the online iTunes store, as of June 24, 2009. Each app was independently coded by two reviewers for its (1) approach to smoking cessation and (2) adherence to the U.S. Public Health Service's 2008 Clinical Practice Guidelines for Treating Tobacco Use and Dependence. Each app was also coded for its (3) frequency of downloads. Apps identified for smoking cessation were found to have low levels of adherence to key guidelines in the index. Few, if any, apps recommended or linked the user to proven treatments such as pharmacotherapy, counseling, and/or a quitline. iPhone apps for smoking cessation rarely adhere to established guidelines for smoking cessation. It is recommended that current apps be revised and future apps be developed around evidence-based practices for smoking cessation. Copyright © 2011 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  16. BookMeUp: Creating a Book Suggestion App

    Science.gov (United States)

    Clark, Jason

    2012-01-01

    The rise of apps and mobile devices has opened the door to small, dedicated software programs that are focused on singular tasks. From the author's perspective as head of digital access and web service manager at Montana State University, these apps offered an opportunity to build a focused digital service aimed at allowing someone to enter a…

  17. Using a Mobile Gaming App to Enhance Accounting Education

    Science.gov (United States)

    Seow, Poh-Sun; Wong, Suay-Peng

    2016-01-01

    The authors describe the first mobile gaming app for learning accounting, Accounting Challenge (ACE). On September 30, 2016, ACE had been downloaded 23,230 times, spanning 90 countries, and had won three international teaching awards. The app was motivated by the aim to empower students to learn accounting in a fun way, outside of the classroom.…

  18. Free Play or Tight Spaces? Mapping Participatory Literacies in Apps

    Science.gov (United States)

    Rowsell, Jennifer; Wohlwend, Karen

    2016-01-01

    Building on existing research applying app maps (Israelson, 2015), the authors take an ideological orientation to broaden app evaluations and consider participatory literacies, social and communicational practices relevant to children's everyday digitally mediated lives. Drawing from their North American elementary classroom studies on children's…

  19. Mobile Apps to Support and Assess Foreign Language Learning

    Science.gov (United States)

    Berns, Anke; Palomo-Duarte, Manuel; Dodero, Juan Manuel; Ruiz-Ladrón, Juan Miguel; Márquez, Andrea Calderón

    2015-01-01

    In the last two decades there have been many attempts to integrate all kinds of mobile devices and apps to support formal as well as informal learning processes. However, most of the available apps still support mainly individual learning, using mobile devices to deliver content rather than providing learners with the opportunity to interact with…

  20. Reading apps for children: Readability from the design perspective

    Science.gov (United States)

    Mohammed, Wasan Abdulwahab; Husni, Husniza

    2017-10-01

    Electronic reading for young children opens new avenues especially with the advance of modern reading devices. The readability of mobile learning applications has received extensive attention by the designers and developers. The reason for such concern is due to its importance in determining usability related issues especially in the design context for children. In many cases, children find it difficult to interact with mobile reading apps. This is because apps for reading and for entertainment require different features. As such, this study sets out three objectives: 1) to evaluate five reading apps for young children from design perspectives; 2) to examine the readability for current existing mobile apps for reading and 3) to propose and evaluate mobile apps UI guideline for readability. Readability indices, observation and interview were conducted on 6 - 8 years old students. The obtained result showed that certain reading apps provide better reading experience for children than others. Some of the reasons are mostly related to the design characteristics embedded within the app. In addition, the use of animation was found to stimulate children reading experience as it is believed to offer the interactivity elements to gain their interest and willingness to read. These findings are believed to provide the recommendations and insights for designers of reading apps for children.

  1. GENIUS & the Swedish Fast Reactor programme

    International Nuclear Information System (INIS)

    Wallenius, Janne

    2012-01-01

    Concluding remarks: Sweden’s growing fast reactor programme focuses on LFR technology, but we also participate in ASTRID. • An innovative facility for UN fabrication, an LBE thermal hydraulics loop and a lead corrosion facility are operational. • A plutonium fuel fabrication lab is is under installation (this week!) • The government is assessing the construction of ELECTRA-FCC, a centre for Gen IV-system R&D, at a tentative cost of ~ 140±20 M€. • Location: Oskarshamn (adjacent to intermediate repository) • Date of criticality: 2023 (best case) • Swedish participation in IAEA TWG-FR should intensify

  2. Barriers between international students and Swedish companies

    OpenAIRE

    Qytyku, Silvana Agolli and Sokol

    2008-01-01

    Title: Barriers between international student’s and Swedish companies Course: Master thesis in business administration, 15 ECTS Date: June 2008 Authors: Silvana Agolli and Sokol Qytyku Supervisor: Dr. Per Eisele In this thesis report we have conduct a primary research on Blekinge area, while it is a shortage of IT workers and at the same time there were a lot of internationals students that graduated every year and didn’t get those available jobs. In this investigation we wanted to find out t...

  3. A History of the Swedish Pension System

    OpenAIRE

    Hagen, Johannes

    2013-01-01

    This report provides an extensive overview of the history of the Swedish pension system. Starting with the implementation of the world's first universal public pension system in 1913, the report discusses the political as well as the economic background to each major public pension reform up until today. It presents the rules and the institutional details of these reforms and discuss their implications for retirement behavior, the general state of the economy and the political environment. Pa...

  4. Reregulation of the Swedish pharmacy sector

    DEFF Research Database (Denmark)

    Wisell, Kristin; Winblad, Ulrika; Sporrong, Sofia Kälvemark

    2015-01-01

    for the reregulation of the Swedish pharmacy sector in 2009. The method used was a qualitative content analysis of written political documents regarding the reregulation. The primary rationales for the reregulation were better availability, efficiency, price pressure, and safe usage of medicines. During...... the preparatory work, the rationales of diversity on the market and entrepreneurship were added, while the original rationales of efficiency, price pressure, and better usage of medicines were abandoned. The reform can be seen as a typical New Public Management reform influenced by the notion that private actors...

  5. Alpine ski sport injuries in Swedish Lapland

    OpenAIRE

    Made, Curt

    2009-01-01

    Downhill skiing is associated with recreation, youth, speed, aerials and crowded courses which carry increased risk of injuries. The aim of this study was to evaluate downhill sport injuries in a Swedish ski resort. Material and methodsIn a case-control study ongoing 1989/90–2006/07, 3,696 injured skiers were registered. After informed consent the injured were assessed by a physician and asked to answer a questionnaire concerning skier, skiing and injury. ResultsAfter three years 481 injured ...

  6. Enhancing Pharmacy Student Learning and Perceptions of Medical Apps

    Science.gov (United States)

    Aungst, Timothy Dy; Brown, Nicole V; Cui, Yan; Tam, Leonard

    2016-01-01

    Background The use of mobile apps in health care is growing. Current and future practitioners must be equipped with the skills to navigate and utilize apps in patient care, yet few strategies exist for training health care professional students on the usage of apps. Objective To characterize first-year pharmacy student use of medical apps, evaluate first-year pharmacy student's perception of skills in finding, evaluating, and using medical apps before and after a focused learning experience, and assess student satisfaction and areas for improvement regarding the learning experience. Methods Students listened to a recorded, Web-based lecture on finding, evaluating, and using mobile apps in patient care. A 2-hour, interactive workshop was conducted during which students were led by an instructor through a discussion on strategies for finding and using apps in health care. The students practiced evaluating 6 different health care–related apps. Surveys were conducted before and after the focused learning experience to assess students' perceptions of medical apps and current use and perspectives on satisfaction with the learning experience and role of technology in health care. Results This educational intervention is the first described formal, interactive method to educate student pharmacists on medical apps. With a 99% response rate, surveys conducted before and after the learning experience displayed perceived improvement in student skills related to finding (52/119, 44% before vs 114/120, 95% after), evaluating (18/119, 15% before vs 112/120, 93% after), and using medical apps in patient care (31/119, 26% before vs 108/120, 90% after) and the health sciences classroom (38/119, 32% before vs 104/120, 87% after). Students described satisfaction with the educational experience and agreed that it should be repeated in subsequent years (89/120, 74% agreed or strongly agreed). Most students surveyed possessed portable electronic devices (107/119, 90% mobile phone) and

  7. Hospital-Owned Apps in Taiwan: Nationwide Survey.

    Science.gov (United States)

    Liu, Hao-Yen; Lee, Wui-Chiang; Sun, Ying-Chou; Fen, Jun-Jeng; Chen, Tzeng-Ji; Chou, Li-Fang; Hwang, Shinn-Jang

    2018-01-16

    Over the last decade, the use of mobile phone apps in the health care industry has grown rapidly. Owing to the high penetration rate of Internet use in Taiwan, hospitals are eager to provide their own apps to improve the accessibility of medical care for patients. The aims of this study were to provide an overview of the currently available hospital-owned apps in Taiwan and to conduct a cross-hospital comparison of app features. In May 2017, the availability of apps from all 414 hospitals in Taiwan was surveyed from the hospital home pages and the Google Play app store. The features of the downloaded apps were then examined in detail and, for each app, the release date of the last update, download frequency, and rating score were obtained from Google Play. Among all the 414 hospitals in Taiwan, 150 (36.2%) owned Android apps that had been made available for public use, including 95% (18/19) of the academic medical centers, 77% (63/82) of the regional hospitals, and 22.0% (69/313) of the local community hospitals. Among the 13 different functionalities made available by the various hospital-owned apps, the most common were the doctor search (100%, 150/150), real-time queue monitoring (100%, 150/150), and online appointment scheduling (94.7%, 142/150) functionalities. The majority of apps (57.3%, 86/150) had a rating greater than 4 out of 5, 49.3% (74/150) had been updated at some point in 2017, and 36.0% (54/150) had been downloaded 10,000 to 50,000 times. More than one-third of the hospitals owned apps intended to increase patient access to health care. The most common app features might reflect the health care situation in Taiwan, where the overcrowded outpatient departments of hospitals operate in an open-access mode without any strict referral system. Further research should focus on the effectiveness and safety of these apps. ©Hao-Yen Liu, Wui-Chiang Lee, Ying-Chou Sun, Jun-Jeng Fen, Tzeng-Ji Chen, Li-Fang Chou, Shinn-Jang Hwang. Originally published in JMIR

  8. APP receptor? To be or not to be…

    Science.gov (United States)

    Deyts, Carole; Thinakaran, Gopal; Parent, Angèle T.

    2016-01-01

    Amyloid Precursor Protein (APP) and its metabolites play a critical role in Alzheimer’s disease pathogenesis. The idea that APP may function as a receptor has gained momentum based on its structural similarities to type I transmembrane receptors, and the identification of putative APP ligands. Here we review the recent experimental evidence in support of this notion and discuss how this concept is viewed in the field. Specifically, we focus on the structural and functional characteristics of APP as a cell surface receptor, and its interaction with adaptors and signaling proteins. We also address the importance of APP's function as a receptor in Alzheimer’s disease etiology and discuss how this function might be potentially important for the development of novel therapeutic approaches. PMID:26837733

  9. Building Android Apps with HTML, CSS, and JavaScript

    CERN Document Server

    Stark, Jonathan

    2010-01-01

    If you know HTML, CSS, and JavaScript, you already have the tools you need to develop Android applications. This hands-on book shows you how to use these open source web standards to design and build apps that can be adapted for any Android device -- without having to use Java. You'll learn how to create an Android-friendly web app on the platform of your choice, and then convert it to a native Android app with the free PhoneGap framework. Discover why device-agnostic mobile apps are the wave of the future, and start building apps that offer greater flexibility and a broader reach. Learn the

  10. GeoMapApp: A Cross-Platform app for Geophysical Data Exploration and Visualisation

    Science.gov (United States)

    Goodwillie, A. M.

    2015-12-01

    Apps that provide convenient, integrated access to a range of geophysical data have wide applicability in both research and teaching. GeoMapApp (http://www.geomapapp.org), a free, map-based data discovery and visualisation tool developed with NSF funding at Lamont-Doherty Earth Observatory provides casual and specialist users alike with intuitive access to hundreds of built-in geoscience data sets covering geophysics, geochemistry, geology, oceanography, and cryospherics. Users can also import their own data tables, spreadsheets, shapefiles, grids, and images. Simple manipulation and analysis tools combined with layering capabilities and engaging visualisations provide a powerful app with which to explore and interrogate geoscience data in its proper geospatial context thus helping users to more easily gain deeper insight and understanding from real-world data. The backbone of GeoMapApp is a regularly-updated multi-resolution elevation base map covering the oceans and continents and includes measurements ranging from Space Shuttle terrestrial data to ultra-high-resolution surveys of coral reefs and seafloor hydrothermal vent fields. Examples of built-in geophysical data sets include interactive earthquake locations and focal mechanism (CMT) solutions; underway cruise track profiles; plate tectonic velocities, seafloor crustal age and heat flow; multi-channel seismic reflection profiles; gravity, magnetic, and geoid anomalies; sidescan; subduction zone interface depths; and, EarthScope station locations. Dynamic links point to data sources and additional information. There are dedicated menus for GeoPRISMS, MARGINS, and Ridge2000 data sets. A versatile profiling tool provides instant access to data cross-sections, and contouring and 3-D views are also offered. Tabular data - both imported and built-in - can be displayed in a variety of ways and users can quickly select data points directly from the map. Layer opacity and on/off toggles allow easy data set

  11. A qualitative study of user perceptions of mobile health apps

    Directory of Open Access Journals (Sweden)

    Wei Peng

    2016-11-01

    Full Text Available Abstract Background Mobile apps for health exist in large numbers today, but oftentimes, consumers do not continue to use them after a brief period of initial usage, are averse toward using them at all, or are unaware that such apps even exist. The purpose of our study was to examine and qualitatively determine the design and content elements of health apps that facilitate or impede usage from the users’ perceptive. Methods In 2014, six focus groups and five individual interviews were conducted in the Midwest region of the U.S. with a mixture of 44 smartphone owners of various social economic status. The participants were asked about their general and health specific mobile app usage. They were then shown specific features of exemplar health apps and prompted to discuss their perceptions. The focus groups and interviews were audio recorded, transcribed verbatim, and coded using the software NVivo. Results Inductive thematic analysis was adopted to analyze the data and nine themes were identified: 1 barriers to adoption of health apps, 2 barriers to continued use of health apps, 3 motivators, 4 information and personalized guidance, 5 tracking for awareness and progress, 6 credibility, 7 goal setting, 8 reminders, and 9 sharing personal information. The themes were mapped to theories for interpretation of the results. Conclusions This qualitative research with a diverse pool of participants extended previous research on challenges and opportunities of health apps. The findings provide researchers, app designers, and health care providers insights on how to develop and evaluate health apps from the users’ perspective.

  12. Using Mobile App Development Tools to Build a GIS Application

    Science.gov (United States)

    Mital, A.; Catchen, M.; Mital, K.

    2014-12-01

    Our group designed and built working web, android, and IOS applications using different mapping libraries as bases on which to overlay fire data from NASA. The group originally planned to make app versions for Google Maps, Leaflet, and OpenLayers. However, because the Leaflet library did not properly load on Android, the group focused efforts on the other two mapping libraries. For Google Maps, the group first designed a UI for the web app and made a working version of the app. After updating the source of fire data to one which also provided historical fire data, the design had to be modified to include the extra data. After completing a working version of the web app, the group used webview in android, a built in resource which allowed porting the web app to android without rewriting the code for android. Upon completing this, the group found Apple IOS devices had a similar capability, and so decided to add an IOS app to the project using a function similar to webview. Alongside this effort, the group began implementing an OpenLayers fire map using a simpler UI. This web app was completed fairly quickly relative to Google Maps; however, it did not include functionality such as satellite imagery or searchable locations. The group finished the project with a working android version of the Google Maps based app supporting API levels 14-19 and an OpenLayers based app supporting API levels 8-19, as well as a Google Maps based IOS app supporting both old and new screen formats. This project was implemented by high school and college students under an SGT Inc. STEM internship program

  13. Targeting ESR1-Mutant Breast Cancer

    Science.gov (United States)

    2015-09-01

    we have developed models of mutant ER driven cancer in which to characterize gene expression. Specifically, tetracycline inducible MCF7 cells that...expression profiling. Figure 1: Degradation of WT and mutant ER with ARN810. MCF7 cells stably transfected with tet-inducible WT and mutant...mutant ER. MCF7 cells stably transfected with tet- inducible WT and mutant ER are treated for 24 hours with estradiol and gene expression profiling

  14. Apps and EFL: A Case Study on the Use of Smartphone Apps to Learn English by Four Japanese University Students

    Science.gov (United States)

    Mindog, Emily

    2016-01-01

    This study explores, describes and analyzes the utilization of smartphone apps by four Japanese university students to support learning English as a Foreign Language (EFL). Findings indicate that intermediate language learners use apps to access content and communicate on SNS and are not keen on studying discrete language parts. Participants…

  15. Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice.

    Science.gov (United States)

    He, Ping; Staufenbiel, Matthias; Li, Rena; Shen, Yong

    2014-12-15

    Normally, sonic hedgehog (Shh) signaling induces high levels of Patched 1 (Ptc1) and its associated transcription factor Gli1 with genesis of specific neuronal progeny. But their roles in the neural stem cells (NSCs), including glial precursor cells (GPCs), of Alzheimer's disease (AD) are unclear. Here, we show that Ptc1 and Gli1 are significantly deficits in the hippocampus of an aged AD transgenic mouse mode, whereas these two molecules are highly elevated at young ages. Our similar findings in autopsied AD brains validate the discovery in AD mouse models. To examine whether Aβ peptides, which are a main component of the amyloid plaques in AD brains, affected Ptc1-Gli1 signaling, we treated GPCs with Aβ peptides, we found that high dose of Aβ1-42 but not Aβ1-40 significantly decreased Ptc1-Gli1, while Shh itself was elevated in hippocampal NSCs/GPCs. Furthermore, we found that deficits of Ptc1-Gli1 signaling induced NSCs/GPCs into asymmetric division, which results in an increase in the number of dividing cells including transit-amplifying cells and neuroblasts. These precursor cells commit to apoptosis-like death under the toxic conditions. By this way, adult neural precursor cell pool is exhausted and defective neurogenesis happens in AD brains. Our findings suggest that Ptc1-Gli1 signaling deregulation resulting abnormal loss of GPCs may contribute to a cognition decline in AD brains. The novel findings elucidate a new molecular mechanism of adult NSCs/GPCs on neurogenesis and demonstrate a regulatory role for Ptc1-Gli1 in adult neural circuit integrity of the brain. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. A Swedish perspective on research ethics review

    Directory of Open Access Journals (Sweden)

    Hans Thulesius, M.D., G.P., Ph.D.

    2010-12-01

    Full Text Available I have participated in writing ethical approval applications for research projects in Sweden a dozen times. I am also since some years a member of the local ethics advisory board in a mostly rural area serving 180.000 people. From that position I advise on what types of local project applications will have to be sent further to the regional ethics committee, REPN in Sweden. With that background I will try to give a brief Swedish perspective on research ethics reviews in general and regarding CGT (classic grounded theory studies using qualitative data in particular.The most famous Swedish example of unethical research is the 1947-1951 Vipeholm sugar trial (Krasse, 2001. Several hundred intellectually and mentally challenged persons at the Vipeholm institution were for years given an excess amount of sugar, mostly in the shape of candy. This resulted in caries that totally ruined the teeth of 50 persons. Of course participants did not give informed consent. Yet, at the time the research was not considered unethical. At least there was no debate about it.

  17. Environmental Orientation in Swedish Local Governments

    Directory of Open Access Journals (Sweden)

    Jan Alpenberg

    2018-02-01

    Full Text Available This study explores the environmental orientation in Swedish local governments. Environmental concerns over potential risk factors have become more important and popular among public organizations and environmental improvement efforts are made to create a sustainable ecosystem for the actors doing business, living and working in the area. Prior research indicates that public organizations have started to become more environmentally oriented in order to take on more responsibilities for reducing their own environmental impact as well as influencing the citizens and local businesses in the direction of a more sustainable way of living and working. Through a survey of Swedish local governments we conclude that they are taking on a key role in developing a sustainable ecosystem through becoming more environmentally oriented. This includes developing a framework for setting environmental goals, identifying suitable environmental indicators and reporting to a wide range of stakeholders. A factor that explains the increasing environmental orientation in the public sector is the implementation of digitalized performance measurement systems. We find that the environmental performance measurements are used to motivate different internal and external stakeholders in the efforts to create a multi-actor ecosystem.

  18. Are boys discriminated in Swedish high schools?

    DEFF Research Database (Denmark)

    Hinnerich, Bjørn Tyrefors; Höglin, Erik; Johannesson, Magnus

    2011-01-01

    Girls typically have higher grades than boys in school and recent research suggests that part of this gender difference may be due to discrimination of boys in grading.Werigorously test this in a field experiment where a random sample of the same tests in the Swedish language is subject to blind ....... The point estimate of the discrimination effect is close to zero with a 95% confidence interval of±4.5% of the average non-blind grade....... and non-blind grading. The non-blind test score is on average 15% lower for boys than for girls. Blind grading lowers the average grades with 13%, indicating that personal ties and/or grade inflation are important in non-blind grading. But we find no evidence of discrimination against boys in grading......Girls typically have higher grades than boys in school and recent research suggests that part of this gender difference may be due to discrimination of boys in grading.Werigorously test this in a field experiment where a random sample of the same tests in the Swedish language is subject to blind...

  19. The Swedish programme for radioactive waste management

    International Nuclear Information System (INIS)

    Bjurstroem, S.; Forsstroem, H.

    1986-10-01

    The following systems and facilities are currently in operation and under implementation: a sea transportation system for all kinds of nuclear waste, a central facility for interim storage of spent fuel (CLAB) and a central underground repository for final disposal of low and medium level reactor waste (SFR). For the remaining steps - final disposal of highly active and longlived radioactive residues - a concept, based on encapsulation of the fuel elements in copper canisters and final storage of the canisters in a repository situated 500 m down in crystalline rock (KBS-3), has been developed and approved by the government in accordance with the Swedish nuclear legislation. Although a feasible method for final disposal of the highly active residues has been shown, the Swedish legislation requires that research be carried out to reach the best possible base for the final decision around the year 2000. In parallel with this a geological investigation programme is carried out to find a suitable site for a final repository. The final site selection is foreseen at the end of the 1990's. All costs for the management of radioactive waste from the nuclear power plants are carried by a fee determined annually. The fee is 0.019 SEK/kWh for 1986

  20. Building Android Apps with HTML, CSS, and JavaScript Making Native Apps with Standards-Based Web Tools

    CERN Document Server

    Stark, Jonathan

    2012-01-01

    It's true: if you know HTML, CSS, and JavaScript, you already have the tools you need to develop Android applications. Now updated for HTML5, the second edition of this hands-on guide shows you how to use open source web standards to design and build apps that can be adapted for any Android device. You'll learn how to create an Android-friendly web app on the platform of your choice, and then use Adobe's free PhoneGap framework to convert it to a native Android app. Discover why device-agnostic mobile apps are the wave of the future, and start building apps that offer greater flexibility and

  1. [Future trend medical apps. From the apps store directly into medical practice?].

    Science.gov (United States)

    Gehring, H; Pramann, O; Imhoff, M; Albrecht, U-V

    2014-12-01

    In day to day medical care, patients, nursing staff and doctors currently face a bewildering and rapidly growing number of health-related apps running on various "smart" devices and there are also uncountable possibilities for the use of such technology. Concerning regulation, a risk-based approach is applied for development and use (including safety and security considerations) of medical and health-related apps. Considering safety-related issues as well as organizational matters, this is a sensible approach but requires honest self-assessment as well as a high degree of responsibility, networking and good quality management by all those involved. This cannot be taken for granted. Apart from regulatory aspects it is important to not only consider what is reasonable, helpful or profitable. Quality aspects, safety matters, data protection and privacy as well as liability issues must also be considered but are often not adequately respected. If software quality is compromised, this endangers patient safety as well as data protection, privacy and data integrity. This can for example result in unwanted advertising or unauthorized access to the stored data by third parties; therefore, local, regional and international regulatory measures need to be applied in order to ensure safe use of medical apps in all possible areas, including the operating room (OR) with its highly specialized demands. Lawmakers need to include impulses from all stakeholders in their considerations and this should include input from existing private initiatives that already deal with the use and evaluation of apps in a medical context. Of course, this process needs to respect pre-existing national, European as well as international (harmonized) standards.

  2. Instant RubyMotion app development

    CERN Document Server

    Laborde, Gant

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This book is a practical, task-based, step-by-step tutorial that will get you started with using RubyMotion to quickly and efficiently write iOS apps.To make the most of this book, you should understand the basics of programming concepts and have a basic understanding of a language similar to Ruby. If you are an Objective-C programmer, you'll learn the advantages of RubyMotion which can access the benefits of Cocoapods, but takes everything a st

  3. Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice.

    Science.gov (United States)

    Chan, Elizabeth S; Chen, Christopher; Cole, Gregory M; Wong, Boon-Seng

    2015-09-08

    It is unclear how human apolipoprotein E4 (ApoE4) increases the risk for Alzheimer's disease (AD). Although Aβ levels can lead to insulin signaling impairment, these experiments were done in the absence of human ApoE. To examine ApoE role, we crossed the human ApoE-targeted replacement mice with mutant human amyloid precursor protein (APP) mice. In 26 week old mice with lower Aβ levels, the expression and phosphorylation of insulin signaling proteins remained comparable among APP, ApoE3xAPP and ApoE4xAPP mouse brains. When the mice aged to 78 weeks, these proteins were markedly reduced in APP and ApoE4xAPP mouse brains. While Aβ can bind to insulin receptor, how ApoE isoforms modulate this interaction remains unknown. Here, we showed that ApoE3 had greater association with insulin receptor as compared to ApoE4, regardless of Aβ42 concentration. In contrast, ApoE4 bound more Aβ42 with increasing peptide levels. Using primary hippocampal neurons, we showed that ApoE3 and ApoE4 neurons are equally sensitive to physiological levels of insulin. However, in the presence of Aβ42, insulin failed to elicit a downstream response only in ApoE4 hippocampal neurons. Taken together, our data show that ApoE genotypes can modulate this Aβ-mediated insulin signaling impairment.

  4. Wild Accessions and Mutant Resources

    DEFF Research Database (Denmark)

    Kawaguchi, Masayoshi; Sandal, Niels Nørgaard

    2014-01-01

    Lotus japonicus, Lotus burttii, and Lotus filicaulis are species of Lotus genus that are utilized for molecular genetic analysis such as the construction of a linkage map and QTL analysis. Among them, a number of mutants have been isolated from two wild accessions: L. japonicus Gifu B-129...

  5. components in induced sorghum mutants

    African Journals Online (AJOL)

    (1984) evaluated induced mutation and hybridisation methods for producing genetic variability in 15 quantitative characters of sorghum. Their results showed large variability in grain yield, plant maturity, plant height and panicles length. Selected mutants with favorable properties can be directly combined in varietal hybrids.

  6. Pro-smoking apps for smartphones: the latest vehicle for the tobacco industry?

    Science.gov (United States)

    BinDhim, Nasser F; Freeman, Becky; Trevena, Lyndal

    2014-01-01

    Smartphone use is growing exponentially and will soon become the only mobile phone handset for about 6 billion users. Smartphones are ideal marketing targets as consumers can be reached anytime, anywhere. Smartphone application (app) stores are global shops that sell apps to users all around the world. Although smartphone stores have a wide collection of health-related apps they also have a wide set of harmful apps. In this study, the availability of 'pro-smoking' apps in two of the largest smartphone app stores (Apple App store and Android Market) was examined. In February 2012, we searched the Apple App Store and Android Market for pro-smoking apps, using the keywords Smoke, Cigarette, Cigar, Smoking and Tobacco. We excluded apps that were not tobacco-related and then assessed the tobacco-related apps against our inclusion criteria. 107 pro-smoking apps were identified and classified into six categories based on functionality.42 of these apps were from the Android Market and downloaded by over 6 million users. Some apps have explicit images of cigarette brands. Tobacco products are being promoted in the new 'smartphone app' medium which has global reach, a huge consumer base of various age groups and underdeveloped regulation. The paper also provides two examples of app store responses to country-specific laws and regulations that could be used to control the harmful contents in the app stores for individual countries.

  7. Development of a Rating Tool for Mobile Cancer Apps: Information Analysis and Formal and Content-Related Evaluation of Selected Cancer Apps.

    Science.gov (United States)

    Böhme, Cathleen; von Osthoff, Marc Baron; Frey, Katrin; Hübner, Jutta

    2017-08-17

    Mobile apps are offered in large numbers and have different qualities. The aim of this article was to develop a rating tool based on formal and content-related criteria for the assessment of cancer apps and to test its applicability on apps. After a thorough analysis of the literature, we developed a specific rating tool for cancer apps based on the MARS (mobile app rating system) and a rating tool for cancer websites. This instrument was applied to apps freely available in stores and focusing on some cancer topic. Ten apps were rated on the basis of 22 criteria. Sixty percent of the apps (6/10) were rated poor and insufficient. The rating by different scientists was homogenous. The good apps had reliable sources were regularly updated and had a concrete intent/purpose in their app description. In contrast, the apps that were rated poor had no distinction of scientific content and advertisement. In some cases, there was no imprint to identify the provider. As apps of poor quality can give misinformation and lead to wrong treatment decisions, efforts have to be made to increase usage of high-quality apps. Certification would help cancer patients to identify reliable apps, yet acceptance of a certification system must be backed up.

  8. Controlling Your "App"etite: How Diet and Nutrition-Related Mobile Apps Lead to Behavior Change.

    Science.gov (United States)

    West, Joshua H; Belvedere, Lindsay M; Andreasen, Rebecca; Frandsen, Christine; Hall, P Cougar; Crookston, Benjamin T

    2017-07-10

    In recent years, obesity has become a serious public health crisis in the United States. Although the problem of obesity is being addressed through a variety of strategies, the use of mobile apps is a relatively new development that could prove useful in helping people to develop healthy dietary habits. Though such apps might lead to health behavior change, especially when relevant behavior change theory constructs are integrated into them, the mechanisms by which these apps facilitate behavior change are largely unknown. The purpose of this study was to identify which behavior change mechanisms are associated with the use of diet- and nutrition-related health apps and whether the use of diet- and nutrition-related apps is associated with health behavior change. A cross-sectional survey was administered to a total of 217 participants. Participants responded to questions on demographics, use of diet and nutrition apps in the past 6 months, engagement and likability of apps, and changes in the participant's dietary behaviors. Regression analysis was used to identify factors associated with reported changes in theory and separately for reported changes in actual behavior, after controlling for potential confounding variables. The majority of study participants agreed or strongly agreed with statements regarding app use increasing their motivation to eat a healthy diet, improving their self-efficacy, and increasing their desire to set and achieve health diet goals. Additionally, majority of participants strongly agreed that using diet/nutrition apps led to changes in their behavior, namely increases in actual goal setting to eat a healthy diet (58.5%, 127/217), increases in their frequency of eating healthy foods (57.6%, 125/217), and increases in their consistency of eating healthy foods (54.4%, 118/217). Participants also responded favorably to questions related to engagement and likability of diet/nutrition apps. A number of predictors were also positively

  9. The Swedish National Defence Research Establishment and the plans for Swedish nuclear weapons

    International Nuclear Information System (INIS)

    Jonter, Thomas

    2001-03-01

    This study analyses the Swedish nuclear weapons research since 1945 carried out by the Swedish National Defence Research Establishment (FOA). The most important aspect of this research was dealing with protection in broad terms against nuclear weapons attacks. However, another aspect was also important from early on - to conduct research aiming at a possible production of nuclear weapons. FOA performed an extended research up to 1968, when the Swedish Government signed the Non-Proliferation Treaty (NPT), which meant the end of these production plans. Up to this date, five main investigations about the technical conditions were made, 1948, 1953, 1955, 1957 and 1965, which all together expanded the Swedish know-how to produce a bomb. The Swedish plans to procure nuclear weapons were not an issue in the debate until the mid 50's. The reason for this was simple, prior to 1954 the plans were secretly held within a small group of involved politicians, military and researchers. The change of this procedure did take place when the Swedish Supreme Commander in a public defence report in 1954 favoured a Swedish Nuclear weapons option. In 1958 FOA had reached a technical level that allowed the Parliament to make a decision. Two programs were proposed - the L-programme (the Loading Programme), to be used if the parliament would say yes to a production of nuclear weapons, and the S-programme (the Protection Programme), if the Parliament would say no. The debate on the issue had now created problems for the Social Democratic Government. The Prime Minister, Tage Erlander, who had earlier defended a procurement of nuclear weapons, was now forced to reach a compromise. The compromise was presented to the parliament in a creative manner that meant that only the S-programme would be allowed. The Government argued that the technical level did allow a 'freedom of action' up to at least the beginning of the 60's when Sweden was mature to make a decision on the issue. During this period

  10. Induced High Lysine Mutants in Barley

    DEFF Research Database (Denmark)

    Doll, Hans; Køie, B.; Eggum, B. O.

    1974-01-01

    variety. Comparisons of six high lysine mutants with the parent variety showed that grain yield and seed size of the mutants are reduced between 10 and 30 per cent. However, the most promising mutant had the lowest reduction in grain yield, and the absolute lysine yield of this mutant was some 30 per cent...... above that of the parent variety. Feeding tests with rats revealed substantial increases in the biological value of the high lysine mutant protein. Also the net protein utilization was improved but less so because of a somewhat reduced digestibility of the mutant protein....

  11. Stakeholder involvement in Swedish nuclear waste management

    Energy Technology Data Exchange (ETDEWEB)

    Elam, Mark; Sundqvist, Goeran [Goeteborg Univ. (Sweden). Section for Science and Technology Studies

    2006-09-15

    This report concerning Swedish nuclear waste management has been produced as part of a cross national research project: CARL - A Social Science Research Project into the Effects of Stakeholder involvement on Decision-Making in Radioactive Waste Management. Besides Sweden, the participating countries are Belgium, Canada, Finland, Slovenia and United Kingdom. A social science research team, working for three years, is in the first phase conducting research in their own countries in order to produce 6 country reports. During the next years the focus will shift to comparisons of stakeholder involvement practices in the participating countries. The report addresses current practices of Swedish nuclear waste management and their historical development. The main focus is on past, current and emerging patterns of stakeholder involvement in the siting of a deep repository for the final disposal of Sweden's spent nuclear fuel. The general questions attended to in the report are: Who are the main stakeholders, and how have they emerged and gained recognition as such? What are the issues currently subject to stakeholder involvement and how have these been decided upon? How is stakeholder involvement organized locally and nationally and how has this changed over time? How has stakeholder involvement gained acceptance as an activity of value in the siting of major waste facilities? The report have attempted to show the development of stakeholder involvement in the siting of a final repository for Sweden's spent nuclear fuel as resembling something other than a straightforward linear process of improvement and refinement. Stakeholder involvement has developed, over the past 15 years or so, into something more like a patchwork of different shapes and forms. Some of the forces that may well contribute to the further elaboration of the patchwork of stakeholder involvement have been pointed out, contingently modifying once more its overall colour and orientation. Questions

  12. Stakeholder involvement in Swedish nuclear waste management

    International Nuclear Information System (INIS)

    Elam, Mark; Sundqvist, Goeran

    2006-09-01

    This report concerning Swedish nuclear waste management has been produced as part of a cross national research project: CARL - A Social Science Research Project into the Effects of Stakeholder involvement on Decision-Making in Radioactive Waste Management. Besides Sweden, the participating countries are Belgium, Canada, Finland, Slovenia and United Kingdom. A social science research team, working for three years, is in the first phase conducting research in their own countries in order to produce 6 country reports. During the next years the focus will shift to comparisons of stakeholder involvement practices in the participating countries. The report addresses current practices of Swedish nuclear waste management and their historical development. The main focus is on past, current and emerging patterns of stakeholder involvement in the siting of a deep repository for the final disposal of Sweden's spent nuclear fuel. The general questions attended to in the report are: Who are the main stakeholders, and how have they emerged and gained recognition as such? What are the issues currently subject to stakeholder involvement and how have these been decided upon? How is stakeholder involvement organized locally and nationally and how has this changed over time? How has stakeholder involvement gained acceptance as an activity of value in the siting of major waste facilities? The report have attempted to show the development of stakeholder involvement in the siting of a final repository for Sweden's spent nuclear fuel as resembling something other than a straightforward linear process of improvement and refinement. Stakeholder involvement has developed, over the past 15 years or so, into something more like a patchwork of different shapes and forms. Some of the forces that may well contribute to the further elaboration of the patchwork of stakeholder involvement have been pointed out, contingently modifying once more its overall colour and orientation. Questions have been

  13. Google Apps - cloud computing v praxi

    OpenAIRE

    Strečko, Marek

    2011-01-01

    This thesis aims to introduce a reader to cloud computing and Google Apps in order to install and use a solution based on Google Apps. First I would like to present basic facts about cloud computing and its division. The following part is dedicated to Google Apps with the history outline of the development of this system and the list of offered versions. Then I would like to describe in details all the most important services, which this system offers, focusing on a practical aspect of the Go...

  14. Smartphone apps for calculating insulin dose: a systematic assessment.

    Science.gov (United States)

    Huckvale, Kit; Adomaviciute, Samanta; Prieto, José Tomás; Leow, Melvin Khee-Shing; Car, Josip

    2015-05-06

    Medical apps are widely available, increasingly used by patients and clinicians, and are being actively promoted for use in routine care. However, there is little systematic evidence exploring possible risks associated with apps intended for patient use. Because self-medication errors are a recognized source of avoidable harm, apps that affect medication use, such as dose calculators, deserve particular scrutiny. We explored the accuracy and clinical suitability of apps for calculating medication doses, focusing on insulin calculators for patients with diabetes as a representative use for a prevalent long-term condition. We performed a systematic assessment of all English-language rapid/short-acting insulin dose calculators available for iOS and Android. Searches identified 46 calculators that performed simple mathematical operations using planned carbohydrate intake and measured blood glucose. While 59% (n = 27/46) of apps included a clinical disclaimer, only 30% (n = 14/46) documented the calculation formula. 91% (n = 42/46) lacked numeric input validation, 59% (n = 27/46) allowed calculation when one or more values were missing, 48% (n = 22/46) used ambiguous terminology, 9% (n = 4/46) did not use adequate numeric precision and 4% (n = 2/46) did not store parameters faithfully. 67% (n = 31/46) of apps carried a risk of inappropriate output dose recommendation that either violated basic clinical assumptions (48%, n = 22/46) or did not match a stated formula (14%, n = 3/21) or correctly update in response to changing user inputs (37%, n = 17/46). Only one app, for iOS, was issue-free according to our criteria. No significant differences were observed in issue prevalence by payment model or platform. The majority of insulin dose calculator apps provide no protection against, and may actively contribute to, incorrect or inappropriate dose recommendations that put current users at risk of both catastrophic overdose and more

  15. Fault in your stars: An Analysis of Android App Reviews

    OpenAIRE

    Aralikatte, Rahul; Sridhara, Giriprasad; Gantayat, Neelamadhav; Mani, Senthil

    2017-01-01

    Mobile app distribution platforms such as Google Play Store allow users to share their feedback about downloaded apps in the form of a review comment and a corresponding star rating. Typically, the star rating ranges from one to five stars, with one star denoting a high sense of dissatisfaction with the app and five stars denoting a high sense of satisfaction. Unfortunately, due to a variety of reasons, often the star rating provided by a user is inconsistent with the opinion expressed in the...

  16. Determinants of adoption of smartphone health apps among college students.

    Science.gov (United States)

    Cho, Jaehee; Quinlan, Margaret M; Park, Dongjin; Noh, Ghee-Young

    2014-11-01

    To examine the effects of cognitive and contingent factors on the adoption of smartphone health apps, focusing on the technology acceptance model (TAM). American college students (N = 422), who currently owned smartphones but were not using health apps, completed an online survey. Results from a path analysis mostly supported the proposed hypotheses, showing that subjective norm, health consciousness, health information orientation, and Internet health information use efficacy significantly affected the main components of TAM. Study findings provide scholars and practitioners with an empirical model of explaining the cognitive and micro-mechanisms of determining the adoption of health apps, especially among younger populations.

  17. Instant EdgeSight for XenApp

    CERN Document Server

    Hasan, Vaqar

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Instant EdgeSight for XenApp is a practical, hands-on guide that contains instruction-based examples from basic to advanced level topics. Instant EdgeSight for XenApp will serve as an excellent source of information for Citrix XenApp professionals and novices alike. It is assumed that readers have experience working with Citrix products and have some sort of familiarity with monitoring.

  18. Psychosocial working conditions and depressive symptoms among Swedish employees

    DEFF Research Database (Denmark)

    Magnusson Hanson, Linda L; Theorell, Töres; Bech, Per

    2009-01-01

    PURPOSE: To investigate prospective associations between working conditions and depressive symptoms in Swedish men and women. METHODS: The study was based on SLOSH (N = 5,985), a follow-up of a representative sample of gainfully employed Swedes 16-64 years of age from the Swedish Work Environment...... authority, support and conflicts at work are predictive of depressive symptoms in the general Swedish working population....... Survey 2003. Work demands, decision authority, support and conflicts at work were measured in 2003. Depressive symptoms were recorded in 2006 by a short version of the depression subscale of the Symptom Checklist 90 (SCL-90). Linear regression analyses were performed. RESULTS: After adjusting...

  19. Women's experiences with using a smartphone app (the Pregnant+ app) to manage gestational diabetes mellitus in a randomised controlled trial.

    Science.gov (United States)

    Skar, Jeanette B; Garnweidner-Holme, Lisa M; Lukasse, Mirjam; Terragni, Laura

    2018-03-01

    The purpose of this study was to explore the experiences of women with gestational diabetes mellitus (GDM) with controlling their blood glucose values and receiving health and nutrition information using a smartphone app (the Pregnant+ app). The study utilised the interpretative phenomenological analysis method. Semi-structured interviews were conducted with 17 participants among those participating to the randomised controlled trial. The women experienced sorrow and disappointment when they were diagnosed with GDM, but they all went through a process of learning to self-manage their condition that was strongly motivated by theirdesire to care for their unborn babies. The women found that the app increased their confidence in their self management of GDM and their motivation for behavioural change. For some women, the app contributed to feelings offrustration or obsession. In addition, some technological problems and a lack of support from health-care professionals limited several women from using the app. The findings suggest that asmartphone app may have potential for supporting women with GDM, particularly in their blood glucose management. However, it also highlights some of the potential challenges of using mHealth technologies. The findings indicate that a closer collaboration between health-care professionals and patients is of great importance in the implementation of apps for women with GDM. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. 77 FR 72864 - Announcement of Requirements and Registration for healthfinder.gov Mobile App Challenge

    Science.gov (United States)

    2012-12-06

    ... healthfinder.gov Mobile App Challenge AGENCY: Office of Disease Prevention and Health Promotion, Office of the... App Challenge to promote the development of a mobile app that will facilitate the customized use of...: December 6, 2012: healthfinder App Challenge is announced on www.challenge.gov and opened for submissions...

  1. Apps for Highlights: our new column for your health management needs

    OpenAIRE

    Chaudhry, Beenish M.

    2016-01-01

    Millions of health and fitness apps are available in online App stores but people are confused about which ones to use and what are the possible benefits of using them. To broaden your understanding about uses and advantages of these mobile apps, every month in this issue, we will focus on a particular health issue and review related mobile apps.

  2. Apps for Highlights: our new column for your health management needs.

    Science.gov (United States)

    Chaudhry, Beenish M

    2016-01-01

    Millions of health and fitness apps are available in online App stores but people are confused about which ones to use and what are the possible benefits of using them. To broaden your understanding about uses and advantages of these mobile apps, every month in this issue, we will focus on a particular health issue and review related mobile apps.

  3. iPad Apps That Promote Mathematical Knowledge? "Yes, They Exist!"

    Science.gov (United States)

    Larkin, Kevin

    2014-01-01

    Having trouble finding the right app? In this article, Kevin Larkin discusses the difficulties teachers encounter when searching the App Store for high quality, appropriate apps that support students' mathematical learning. Kevin provides a useful link to a collection of over 100 app reviews.

  4. The Quality and Accuracy of Mobile Apps to Prevent Driving After Drinking Alcohol.

    Science.gov (United States)

    Wilson, Hollie; Stoyanov, Stoyan R; Gandabhai, Shailen; Baldwin, Alexander

    2016-08-08

    Driving after the consumption of alcohol represents a significant problem globally. Individual prevention countermeasures such as personalized mobile app aimed at preventing such behavior are widespread, but there is little research on their accuracy and evidence base. There has been no known assessment investigating the quality of such apps. This study aimed to determine the quality and accuracy of apps for drink driving prevention by conducting a review and evaluation of relevant mobile apps. A systematic app search was conducted following PRISMA guidelines. App quality was assessed using the Mobile App Rating Scale (MARS). Apps providing blood alcohol calculators (hereafter "calculators") were reviewed against current alcohol advice for accuracy. A total of 58 apps (30 iOS and 28 Android) met inclusion criteria and were included in the final analysis. Drink driving prevention apps had significantly lower engagement and overall quality scores than alcohol management apps. Most calculators provided conservative blood alcohol content (BAC) time until sober calculations. None of the apps had been evaluated to determine their efficacy in changing either drinking or driving behaviors. This novel study demonstrates that most drink driving prevention apps are not engaging and lack accuracy. They could be improved by increasing engagement features, such as gamification. Further research should examine the context and motivations for using apps to prevent driving after drinking in at-risk populations. Development of drink driving prevention apps should incorporate evidence-based information and guidance, lacking in current apps.

  5. Persian mHealth Apps: A Cross Sectional Study Based on Use Case Classification.

    Science.gov (United States)

    Saeedi, Marjan Ghazi; Kalhori, Sharareh Rostam Niakan; Nouria, Rasool; Yasini, Mobin

    2016-01-01

    Mobile health apps play an important role in healthcare processes and health promotion. In recent years many Persian mhealth apps were developed and are available in various national app markets. Cafebazaar is the largest Persian app store that contains more than 3500 android apps in medical and health & fitness categories. In this study some characteristics of 200 top Persian medical apps of Cafebazaar were investigated and then categorized by their use cases. Results showed that only 6% of apps declare the involvement of at least one health professional in the conception or development of the apps. In 35% of studied apps, no contact information was provided for the users and 10.5% applied reliable sources for their content. 13 distinct use cases were found in all 200 apps of which two were new to an already published use-case model. This study shows that Persian mHealth apps, like other existing apps in the world, have a long way to improve and reach some basic standards. Lack of regulatory agencies and absence of a dynamic evaluation system for mHealth apps might be the main reason of these defects. This study also shows that 20 use cases existing in international health related apps are not yet used in Persian apps and therefore there is a reach potential of creating new apps in mHealth field.

  6. Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.

    Science.gov (United States)

    Nam, Kyong Nyon; Wolfe, Cody M; Fitz, Nicholas F; Letronne, Florent; Castranio, Emilie L; Mounier, Anais; Schug, Jonathan; Lefterov, Iliya; Koldamova, Radosveta

    2018-01-01

    Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder that is influenced by genetic and environmental risk factors, such as inheritance of ε4 allele of APOE (APOE4), sex and diet. Here, we examined the effect of high fat diet (HFD) on amyloid pathology and expression profile in brains of AD model mice expressing human APOE isoforms (APP/E3 and APP/E4 mice). APP/E3 and APP/E4 mice were fed HFD or Normal diet for 3months. We found that HFD significantly increased amyloid plaques in male and female APP/E4, but not in APP/E3 mice. To identify differentially expressed genes and gene-networks correlated to diet, APOE isoform and sex, we performed RNA sequencing and applied Weighted Gene Co-expression Network Analysis. We determined that the immune response network with major hubs Tyrobp/DAP12, Csf1r, Tlr2, C1qc and Laptm5 correlated significantly and positively to the phenotype of female APP/E4-HFD mice. Correspondingly, we found that in female APP/E4-HFD mice, microglia coverage around plaques, particularly of larger size, was significantly reduced. This suggests altered containment of the plaque growth and sex-dependent vulnerability in response to diet. The results of our study show concurrent impact of diet, APOE isoform and sex on the brain transcriptome and AD-like phenotype. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Swedish Taxation in a 150-year Perspective

    Directory of Open Access Journals (Sweden)

    Stenkula Mikael

    2014-11-01

    Full Text Available This paper examines the development of taxation in Sweden from 1862 to 2010. The examination includes six key aspects of the Swedish tax system, namely the taxation of labor income, capital income, wealth, inheritances and gifts, consumption and real estate. The importance of these taxes varied greatly over time and Sweden increasingly relied on broad-based taxes (such as income taxes and general consumption taxes and taxes that were less visible to the public (such as payroll taxes and social security contributions. The tax-to-GDP ratio was initially low and relatively stable, but from the 1930s, the ratio increased sharply for nearly 50 years. Towards the end of the period, the tax-to-GDP ratio declined significantly.

  8. Gendered portraits of depression in Swedish newspapers.

    Science.gov (United States)

    Bengs, Carita; Johansson, Eva; Danielsson, Ulla; Lehti, Arja; Hammarström, Anne

    2008-07-01

    Mass media are influential mediators of information, knowledge, and narratives of health and illness. In this article, we report on an examination of personal accounts of illness as presented in three Swedish newspapers, focusing on the gendered representation of laypersons' experiences of depression. A database search identified all articles mentioning depression during the year 2002. Twenty six articles focusing on personal experiences of depression were then subjected to a qualitative content analysis. We identified four themes: displaying a successful facade, experiencing a cracking facade, losing and regaining control, and explaining the illness. We found both similarities and differences with regard to gendered experiences. The mediated accounts of depression both upheld and challenged traditional gender stereotypes. The women's stories were more detailed, relational, emotionally oriented, and embodied. The portrayal of men was less emotional and expressive, and described a more dramatic onset of depression, reflecting hegemonic patterns of masculinity.

  9. Offshoring practices of Danish and Swedish SMEs

    DEFF Research Database (Denmark)

    Wæhrens, Brian Vejrum; Slepniov, Dmitrij; Johansen, John

    2015-01-01

    networks. Although still in their infancy, these networks are, as expected, creating new demands for their home bases in terms of demands for formalisation of work processes, systems development and managerial capability related to orchestrating operations across national borders, but more fundamentally......This paper examines how small and medium enterprises (SMEs) configure their operations on the global scale and how this affects their home bases in terms of operations requirements and priorities. In order to relate SMEs’ offshoring initiatives with their operations configuration attributes, we...... draw on the operations networks literature and survey responses from 675 Danish and 410 Swedish companies. On the basis of the survey results, we find that although the SMEs are less experienced and less advanced in their offshoring ventures than large companies, they are building dispersed operations...

  10. Operating experience from Swedish nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    During 1997 the PWRs in Ringhals performed extremely well (capability factors 85-90%), the unit Ringhals 2 reached the best capability factor since commercial operation started in 1976. The BWRs made an average 76% capability, which is somewhat less than in 1996. The slightly reduced capability derives from ongoing modernization projects at several units. At the youngest plants, Forsmark 3 and Oskarshamn 3, capability and utilization were very high. Events and data for 1997 are given for each reactor, together with operational statistics for the years 1990-1997. A number of safety-related events are reported, which occurred st the Swedish plants during 1997. These events are classified as level 1 or higher on the international nuclear event scale (INES).

  11. Perceived employability trajectories: A Swedish cohort study.

    Science.gov (United States)

    Törnroos Née Kirves, Kaisa; Bernhard-Oettel, Claudia; Leineweber, Constanze

    2017-07-27

    This study identified perceived employability trajectories and their associations with sleeping difficulties and depressive symptoms over time. The sample was part of the Swedish Longitudinal Survey on Health from 2008 to 2014 (n=4,583). Two stable trajectories (high and low perceived employability over time) and three trajectories with changes (increasing, decreasing, and V-shaped perceived employability over time) were identified. Workers with stable low perceived employability reported more sleeping difficulties and depressive symptoms than those who perceived high or increasing employability. Perceived employability is a rather stable personal resource, which is associated with well-being over time. However, changes in perceived employability do not seem to be echoed in well-being, at least not as immediately as theoretically expected.

  12. Fostering Perspectives on Swedish and Indian Culture

    Directory of Open Access Journals (Sweden)

    Harveen Kaur

    2018-02-01

    Full Text Available This article is a reflection of cultural differences recorded by the author during her research visit to Sweden in the year 2017 (February-March month. The objectives of the research visit included understanding official dialects of both countries, existing education system and work environments, variant food habits, family structure and associations, available transport systems, sustainable living options and cultural exchange within India and Sweden. The information was first collected through existing literature and was supported by information collected through observation method, informal discussions and interactions with the Swedish people. It can be concluded that both countries are culturally very different and different parts of each country further exhibit alteration in cultural practices, languages and food preferences. Some variations are also due to population size in both countries. For instance, transportation is very well developed in developed countries due to the availability of advanced technology and less population.

  13. A Swedish national adoption study of criminality

    Science.gov (United States)

    Kendler, K. S.; Lönn, S. Larsson; Morris, N. A.; Sundquist, J.; Långström, N.; Sundquist, K.

    2014-01-01

    Background To clarify the role of genetic and environmental factors in criminal behavior (CB), we examined all CB and violent and non-violent subtypes (VCB and NVCB, respectively) in a Swedish national sample of adoptees and their relatives. Method CB was defined by a conviction in the Swedish Crime Register with standard definitions for VCB and NVCB subtypes. We examined adoptees born 1950–1991 (n=18070) and their biological (n=79206) and adoptive (n=47311) relatives. Results The risk for all CB was significantly elevated in the adopted-away offspring of biological parents of which at least one had CB [odds ratio (OR) 1.5, 95% confidence interval (CI) 1.4–1.6] and in the biological full and half-siblings of CB adoptees (OR 1.4, 95% CI 1.2–1.6 and OR 1.3, 95% CI 1.2–1.3, respectively). A genetic risk index (including biological parental/sibling history of CB and alcohol abuse) and an environmental risk index (including adoptive parental and sibling CB and a history of adoptive parental divorce, death, and medical illness) both strongly predicted probability of CB. These genetic and environmental risk indices acted additively on adoptee risk for CB. Moderate specificity was seen in the transmission of genetic risk for VCB and NVCB between biological parents and siblings and adoptees. Conclusions CB is etiologically complex and influenced by a range of genetic risk factors including a specific liability to CB and a vulnerability to broader externalizing behaviors, and by features of the adoptive environment including parental CB, divorce and death. Genetic risk factors for VCB and NVCB may be at least partially distinct. PMID:24180693

  14. Digital Components in Swedish NPP Power Systems

    International Nuclear Information System (INIS)

    Karlsson, Mattias; Eriksson, Tage

    2015-01-01

    Swedish nuclear power plants have over the last 20 years of operation modernised or exchanged several systems and components of the electrical power system. Within these works, new components based on digital technology have been employed in order to realize functionality that was previously achieved by using electro-mechanical or analogue technology. Components and systems such as relay protection, rectifiers, inverters, variable speed drives and diesel-generator sets are today equipped with digital components. Several of the systems and components fulfil functions with a safety-role in the NPP. Recently, however, a number of incidents have occurred which highlight deficiencies in the design or HMI of the equipment, which warrants questions whether there are generic problems with some applications of digital components that needs to be addressed. The use of digital components has presented cost effective solutions, or even the only available solution on the market enabling a modernisation. The vast majority of systems using digital components have been operating without problems and often contribute to improved safety but the challenge of non-detectable, or non-identifiable, failure modes remain. In this paper, the extent to which digital components are used in Swedish NPP power systems will be presented including a description of typical applications. Based on data from maintenance records and fault reports, as well as interviews with designers and maintenance personnel, the main areas where problems have been encountered and where possible risks have been identified will be described. The paper intends to investigate any 'tell-tales' that could give signals of unwanted behaviour. Furthermore, particular benefits experienced by using digital components will be highlighted. The paper will also discuss the safety relevance of these findings and suggest measures to improve safety in the application of digital components in power systems. (authors)

  15. Evaluation of COTS Rad Detection Apps

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Eric [National Security Technologies, LLC. (NSTec), Mercury, NV (United States)

    2014-02-01

    Mobile applications are currently under distribution to smart phones utilizing the built-in charge coupled-device (CCD) camera as a radiation detector. The CCD detector has a very low but measurable gamma interaction cross section so the mechanism is feasible, especially for higher dose rate environments. Given that in a large release of radioactive material these ‘crowd sourced’ measurements will be put forth for consideration, a testing and evaluation of the accuracy and uncertainty of the Apps is a critical endeavor. Not only is the accuracy of the reported measurement of concern to the immediate user’s safety, a quantitative uncertainty is required for a government response such as the Federal Radiological Monitoring and Assessment Center (FRMAC) to accept the values for consideration in the determination of regions exceeding protective action guidelines. Already, prompted by the Fukushima nuclear material releases, several repositories of this crowd-sourced data have been created (http://japan.failedrobot.com, http://www.stubbytour.com/nuc/index_en.asp, and http://www.rdtn.org) although the question remains as to the reliability of measurements incorporated into these repositories. In cases of conflict between the real-time published crowd-sourced data and governmental protective actions prepared literature should be on-hand documenting why the difference, if any, exists. Four applications for iOS devices were obtained along with hardware to benchmark their performance. Gamma/X-Ray Detector by Stephan Hotto, Geiger Camera by Senscare, and RadioactivityCounter App by Hotray LTD are all the applications available for distribution within the US that utilize the CCD camera sensor for detection of radiation levels. The CellRad app under development by Idaho National Laboratory for the Android platform was evaluated. In addition, iRad Geiger with the associated hardware accessory was also benchmarked. Radiation fields were generated in a Cs-137 JL Shepherd

  16. Evaluation of COTS Rad Detection Apps

    International Nuclear Information System (INIS)

    Wagner, Eric

    2014-01-01

    Mobile applications are currently under distribution to smart phones utilizing the built-in charge coupled-device (CCD) camera as a radiation detector. The CCD detector has a very low but measurable gamma interaction cross section so the mechanism is feasible, especially for higher dose rate environments. Given that in a large release of radioactive material these 'crowd sourced' measurements will be put forth for consideration, a testing and evaluation of the accuracy and uncertainty of the Apps is a critical endeavor. Not only is the accuracy of the reported measurement of concern to the immediate user's safety, a quantitative uncertainty is required for a government response such as the Federal Radiological Monitoring and Assessment Center (FRMAC) to accept the values for consideration in the determination of regions exceeding protective action guidelines. Already, prompted by the Fukushima nuclear material releases, several repositories of this crowd-sourced data have been created (http://japan.failedrobot.com, http://www.stubbytour.com/nuc/index_en.asp, and http://www.rdtn.org) although the question remains as to the reliability of measurements incorporated into these repositories. In cases of conflict between the real-time published crowd-sourced data and governmental protective actions prepared literature should be on-hand documenting why the difference, if any, exists. Four applications for iOS devices were obtained along with hardware to benchmark their performance. Gamma/X-Ray Detector by Stephan Hotto, Geiger Camera by Senscare, and RadioactivityCounter App by Hotray LTD are all the applications available for distribution within the US that utilize the CCD camera sensor for detection of radiation levels. The CellRad app under development by Idaho National Laboratory for the Android platform was evaluated. In addition, iRad Geiger with the associated hardware accessory was also benchmarked. Radiation fields were generated in a Cs-137 JL

  17. Using apps for learning across the curriculum a literacy-based framework and guide

    CERN Document Server

    Beach, Richard

    2014-01-01

    How can apps be used to foster learning with literacy across the curriculum? This book offers both a theoretical framework for considering app affordances and practical ways to use apps to build students' disciplinary literacies and to foster a wide range of literacy practices.Using Apps for Learning Across the Curriculumpresents a wide range of different apps and also assesses their value features methods for and apps related to planning instruction and assessing student learning identifies favorite apps whose affordances are most likely to foster certain disciplinary literacies includes reso

  18. A Hierarchical Framework for Evaluation and Informed Decision Making Regarding Smartphone Apps for Clinical Care.

    Science.gov (United States)

    Torous, John Blake; Chan, Steven Richard; Gipson, Shih Yee-Marie Tan; Kim, Jung Won; Nguyen, Thuc-Quyen; Luo, John; Wang, Philip

    2018-02-15

    With thousands of smartphone apps targeting mental health, it is difficult to ignore the rapidly expanding use of apps in the treatment of psychiatric disorders. Patients with psychiatric conditions are interested in mental health apps and have begun to use them. That does not mean that clinicians must support, endorse, or even adopt the use of apps, but they should be prepared to answer patients' questions about apps and facilitate shared decision making around app use. This column describes an evaluation framework designed by the American Psychiatric Association to guide informed decision making around the use of smartphone apps in clinical care.

  19. Mutant genes in pea breeding

    International Nuclear Information System (INIS)

    Swiecicki, W.K.

    1990-01-01

    Full text: Mutations of genes Dpo (dehiscing pods) and A (anthocyanin synthesis) played a role in pea domestication. A number of other genes were important in cultivar development for 3 types of usage (dry seeds, green vegetable types, fodder), e.g. fn, fna, le, p, v, fas and af. New genes (induced and spontaneous), are important for present ideotypes and are registered by the Pisum Genetics Association (PGA). Comparison of a pea variety ideotype with the variation available in gene banks shows that breeders need 'new' features. In mutation induction experiments, genotype, mutagen and method of treatment (e.g. combined or fractionated doses) are varied for broadening the mutation spectrum and selecting more genes of agronomic value. New genes are genetically analysed. In Poland, some mutant varieties with the gene afila were registered, controlling lodging by a shorter stem and a higher number of internodes. Really non-lodging pea varieties could strongly increase seed yield. But the probability of detecting a major gene for lodging resistance is low. Therefore, mutant genes with smaller influence on plant architecture are sought, to combine their effect by crossing. Promising seem to be the genes rogue, reductus and arthritic as well as a number of mutant genes not yet genetically identified. The gene det for terminal inflorescence - similarly to Vicia faba - changes plant development. Utilisation of assimilates and ripening should be better. Improvement of harvest index should give higher seed yield. A number of genes controlling disease resistance are well known (eg. Fw, Fnw, En, mo and sbm). Important in mass screening of resistance are closely linked gene markers. Pea gene banks collect respective lines, but mutants induced in highly productive cultivars would be better. Inducing gene markers sometimes seems to be easier than transfer by crossing. Mutation induction in pea breeding is probably more important because a high number of monogenic features are

  20. There is an app for that - Or is there? A content analysis of publicly available smartphone apps for managing alcohol use.

    Science.gov (United States)

    Hoeppner, Bettina B; Schick, Melissa R; Kelly, Lourah M; Hoeppner, Susanne S; Bergman, Brandon; Kelly, John F

    2017-11-01

    Smartphone apps are emerging as a promising tool to support recovery from and prevention of problematic alcohol use, yet it is unclear what type of apps are currently available in the public domain, and to what degree these apps use interactive tailoring or other dynamic features to meet users' specific needs. We conducted a content analysis of Android apps for managing drinking available on Google Play (n=266), downloaded between November 21, 2014 and June 25, 2015. We recorded app popularity (>10,000 downloads) and user-rated quality (number of stars) from Google Play, and coded the apps on three domains (basic descriptors, functionality, use of dynamic features). In total, the reviewed 266 apps were downloaded at least 2,793,567 times altogether. The most common types of app were BAC calculators (37%), information provision apps (37%), tracking calendars (24%), and motivational tools (21%). Most apps were free (65%) or low in cost (mean=$3.76; SD=$5.80). Many apps provided at least some level of tailored feedback (60%), but the extent of tailoring was limited. Use of other dynamic features (i.e., push notifications, passive data collection) was largely absent. Univariate models predicting app popularity (i.e., >10,000 downloads vs. not) and user-rated quality (i.e., star rating) indicated that tailoring was positively related to popularity (OR=2.41 [1.30-4.46]), and the existence of time-based tailoring (e.g., tracking) was related to quality (b=0.48 [0.19-0.77]). These apps have a wide public health reach with >2.7 million total combined downloads to date. A wide variety of apps exist, allowing persons interested in using apps to help them manage their drinking to choose from numerous types of supports. Tailoring, while related favorably to an app's popularity and user-rated quality, is limited in publicly available apps. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Automated smartphone audiometry: Validation of a word recognition test app.

    Science.gov (United States)

    Dewyer, Nicholas A; Jiradejvong, Patpong; Henderson Sabes, Jennifer; Limb, Charles J

    2018-03-01

    Develop and validate an automated smartphone word recognition test. Cross-sectional case-control diagnostic test comparison. An automated word recognition test was developed as an app for a smartphone with earphones. English-speaking adults with recent audiograms and various levels of hearing loss were recruited from an audiology clinic and were administered the smartphone word recognition test. Word recognition scores determined by the smartphone app and the gold standard speech audiometry test performed by an audiologist were compared. Test scores for 37 ears were analyzed. Word recognition scores determined by the smartphone app and audiologist testing were in agreement, with 86% of the data points within a clinically acceptable margin of error and a linear correlation value between test scores of 0.89. The WordRec automated smartphone app accurately determines word recognition scores. 3b. Laryngoscope, 128:707-712, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  2. CELSTEC Learning Labs: Mobile App Development for Education and Training

    NARCIS (Netherlands)

    Specht, Marcus

    2011-01-01

    Specht, M. (2011). CELSTEC Learning Labs: Mobile App Development for Education and Training. Presentation given in Workshop at CELSTEC Learning Lab for Bluetea. February, 21, 2011, Heerlen, The Netherlands.

  3. Appreneur secrets to success in the app store

    CERN Document Server

    Pierce, Taylor

    2013-01-01

    You are interested in making an app. You have read all of the stories of successful developers and appreneurs. You are determined to get a piece of the pie. The world of apps is the fastest growing market in the world today, and it is here to stay. The best part is you can get in on it! Now what if I told you that without the knowledge contained in this book the odds of you making a profit are slim to none? What if I also told you that you probably wouldn't break even? There is more to apps than most people think. The average person assumes that if they make an app, they will instantly become

  4. Saint Louis Encephalitis Temperature-Sensitive Mutants.

    Science.gov (United States)

    1981-01-01

    group II contains two mutants and group III contains three mutants. Examination of the ability of mutants to grow at 300C, 40 C or 37 C indicates that...importance. Information from studies with Poliovirus has shown that the use of live attenuated virus vaccines result in longer lasting, more effec- tive...sensitive mutant to grow at internal body temperature may have a significant effect on the ability of the virus to induce a protective immune response or

  5. Possibilities of implementing nitrogen removal at Swedish wastewater treatment plants

    International Nuclear Information System (INIS)

    Hultman, Bengt; Plaza, Elzbieta; Tendaj-Xavier, Marta

    1987-01-01

    Problems related to eutrophication and oxygen consumption have been considered as the major factors in deterioration of the water quality in Swedish lakes, rivers and coastal areas. Technical solutions to reduce oxygen-consuming materials and eutrophication have up to now been directed towards the removal of biochemical oxygen demand (BOD) and phosphorus. Thus, biological and chemical treatment of municipal wastewater is usually prescribed, and at present about 90% of the municipal wastewater from Swedish urban areas is treated both biologically and chemically. Most plants are designed for post-precipitation, although the treatment plants may now be operated in a modified way, for example, with the use of preprecipitation, two-point precipitation or recirculation of chemical sludges. Hultman and Moore (1982) have presented an overview of Swedish practice in municipal wastewater treatment. Although Swedish treatment of municipal wastewater concentrates on the removal of biochemical oxygen demand and phosphorus, the environmental and operational effects of nitrogen have been discussed for many years

  6. Can a smartphone app improve medical trainees' knowledge of antibiotics?

    Science.gov (United States)

    Fralick, Michael; Haj, Reem; Hirpara, Dhruvin; Wong, Karen; Muller, Matthew; Matukas, Larissa; Bartlett, John; Leung, Elizabeth; Taggart, Linda

    2017-11-30

    To determine whether a smartphone app, containing local bacterial resistance patterns (antibiogram) and treatment guidelines, improved knowledge of prescribing antimicrobials among medical trainees. We conducted a prospective, controlled, pre-post study of medical trainees with access to a smartphone app (app group) containing our hospital's antibiogram and treatment guidelines compared to those without access (control group). Participants completed a survey which included a knowledge assessment test (score range, 0 [lowest possible score] to 12 [highest possible score]) at the start of the study and four weeks later. The primary outcome was change in mean knowledge assessment test scores between week 0 and week 4. Change in knowledge assessment test scores in the app group were compared to the difference in scores in the control group using multivariable linear regression. Sixty-two residents and senior medical students participated in the study. In a multivariable analysis controlling for sex and prior knowledge, app use was associated with a 1.1 point (95% CI: 0.10, 2.1) [β = 1.08, t(1) = 2.08, p = 0.04]  higher change in knowledge score compared to the change in knowledge scores in the control group. Among those in the app group, 88% found it easy to navigate, 85% found it useful, and about one- quarter used it daily. An antibiogram and treatment algorithm app increased knowledge of prescribing antimicrobials in the context of local antibiotic resistance patterns. These findings reinforce the notion that smartphone apps can be a useful and innovative means of delivering medical education.

  7. SOME ASPECTS OF USING GOOGLE APPS INTO HIGHER EDUCATIONAL INSTITUTION

    OpenAIRE

    V. Oleksyuk

    2013-01-01

    The article investigated the concept of information and educational space» and determined the aspects of integration of its services. The unified authentication is an important component of information and educational space. It can be based on LDAP-directory. This study presented the main advantages of using Google Apps in process of learning. We described the experience of the integration Google Apps into information and educational space of Department of Physics and Mathematics of Ternopil ...

  8. iPhone Location Aware Apps by Example - Beginners Guide

    CERN Document Server

    Chawdhary, Zeeshan

    2012-01-01

    Using a By example approach you will master the essentials of location awareness and augmented reality by building five complete apps using easy to follow step by step instructions geared towards newcomers. Novice to professional level iOS programmers who want to master location awareness and augmented reality. Build five practical location-based iOS Apps from scratch, a first for any book, converting learning into actual implementation.

  9. Accuracy of smartphone apps for heart rate measurement.

    Science.gov (United States)

    Coppetti, Thomas; Brauchlin, Andreas; Müggler, Simon; Attinger-Toller, Adrian; Templin, Christian; Schönrath, Felix; Hellermann, Jens; Lüscher, Thomas F; Biaggi, Patric; Wyss, Christophe A

    2017-08-01

    Background Smartphone manufacturers offer mobile health monitoring technology to their customers, including apps using the built-in camera for heart rate assessment. This study aimed to test the diagnostic accuracy of such heart rate measuring apps in clinical practice. Methods The feasibility and accuracy of measuring heart rate was tested on four commercially available apps using both iPhone 4 and iPhone 5. 'Instant Heart Rate' (IHR) and 'Heart Fitness' (HF) work with contact photoplethysmography (contact of fingertip to built-in camera), while 'Whats My Heart Rate' (WMH) and 'Cardiio Version' (CAR) work with non-contact photoplethysmography. The measurements were compared to electrocardiogram and pulse oximetry-derived heart rate. Results Heart rate measurement using app-based photoplethysmography was performed on 108 randomly selected patients. The electrocardiogram-derived heart rate correlated well with pulse oximetry ( r = 0.92), IHR ( r = 0.83) and HF ( r = 0.96), but somewhat less with WMH ( r = 0.62) and CAR ( r = 0.60). The accuracy of app-measured heart rate as compared to electrocardiogram, reported as mean absolute error (in bpm ± standard error) was 2 ± 0.35 (pulse oximetry), 4.5 ± 1.1 (IHR), 2 ± 0.5 (HF), 7.1 ± 1.4 (WMH) and 8.1 ± 1.4 (CAR). Conclusions We found substantial performance differences between the four studied heart rate measuring apps. The two contact photoplethysmography-based apps had higher feasibility and better accuracy for heart rate measurement than the two non-contact photoplethysmography-based apps.

  10. Predictors of Utilization of a Novel Smoking Cessation Smartphone App.

    Science.gov (United States)

    Zeng, Emily Y; Vilardaga, Roger; Heffner, Jaimee L; Mull, Kristin E; Bricker, Jonathan B

    2015-12-01

    Understanding the characteristics of high and low utilizers of smartphone applications (apps) for smoking cessation would inform development of more engaging and effective apps, yet no studies to date have addressed this critical question. Informed by prior research on predictors of cessation Web site utilization, this study examines the degree to which baseline demographic factors (gender, age, and education), smoking-related factors (smoking level and friends' smoking), and psychological factors (depression and anxiety) are predictive of utilization of a smartphone app for smoking cessation called SmartQuit. Data came from 98 participants randomized to SmartQuit as part of a pilot trial from March to May 2013. We used negative binomial count regressions to examine the relationship between user characteristics and utilization of the app over an 8-week treatment period. Lower education (risk ratio [RR]=0.492; p=0.021), heavier smoking (RR=0.613; p=0.033), and depression (RR=0.958; p=0.017) prospectively predicted lower app utilization. Women (RR=0.320; p=0.022), those with lower education (RR=0.491; p=0.013), and heavier smokers (RR=0.418; p=0.039) had lower utilization of app features known to predict smoking cessation. Many of the predictors of utilization of smoking cessation apps are the same as those of cessation Web sites. App-delivered smoking cessation treatment effectiveness could be enhanced by focusing on increasing engagement of women, those with lower education, heavy smokers, and those with current depressive symptoms.

  11. Specialized Binary Analysis for Vetting Android APPS Using GUI Logic

    Science.gov (United States)

    2016-04-01

    unavailable. These techniques make it possible to vet a large number of Android apps in a timely and cost -effective manner. 15. SUBJECT TERMS... Malware Detection for Android applications, Binary Analysis 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 19a...techniques make it possible to vet a large number of Android apps in a timely and cost -effective manner. The project develops 4 complementary

  12. Using GeoMapApp in the Classroom

    Science.gov (United States)

    Goodwillie, A. M.

    2017-12-01

    The GeoMapApp tool has been updated with enhanced functionality that is useful in the classroom. Hosted as a service of the IEDA Facility at Columbia University, GeoMapApp (http://www.geomapapp.org) is a free resource that integrates a wide range of research-grade geoscience data in one intuitive map-based interface. It includes earthquake and volcano data, geological maps, plate tectonic data sets, and a high-resolution topography/bathymetry base map. Users can also import and analyse their own data files. Layering and transparency capabilities allow users to compare multiple data sets at once. The GeoMapApp interface presents data in its proper geospatial context, helping students more easily gain insight and understanding from the data. Simple tools for data manipulation allow students to analyse the data in different ways such as generating profiles and producing visualisations for reports. The new Save Session capability is designed to assist in the classroom: The educator saves a pre-loaded state of GeoMapApp. When shared with the class, the saved session file allows students to open GeoMapApp with exactly the same data sets loaded and the same display parameters chosen thus freeing up valuable time in which students can explore the data. In this presentation, activities related to plate tectonics will be highlighted. One activity helps students investigate plate boundaries by exploring earthquake and volcano locations. Another requires students to calculate the rate of seafloor spreading using crustal age data in various ocean basins. A third uses the GeoMapApp layering technique to explore the influence of geological forces in shaping the landscape. Educators report that using GeoMapApp in the classroom lowers the barriers to data accessibility for students; fosters an increased sense of data "ownership" - GeoMapApp presents the same data in the same tool used by researchers; allows engagement with authentic geoscience data; promotes STEM skills and

  13. Static Analysis of Android Apps: A Systematic Literature Review

    OpenAIRE

    Li, Li; Bissyande, Tegawendé François D Assise; Papadakis, Mike; Rasthofer, Siegfried; Bartel, Alexandre; Octeau, Damien; Klein, Jacques; Le Traon, Yves

    2017-01-01

    Context: Static analysis exploits techniques that parse program source code or bytecode, often traversing program paths to check some program properties. Static analysis approaches have been proposed for different tasks, including for assessing the security of Android apps, detecting app clones, automating test cases generation, or for uncovering non-functional issues related to performance or energy. The literature thus has proposed a large body of works, each of which attempts to tackle one...

  14. Pro-smoking apps: where, how and who are most at risk.

    Science.gov (United States)

    BinDhim, Nasser F; Freeman, Becky; Trevena, Lyndal

    2015-03-01

    Pro-smoking applications (app) provide information about brands of tobacco products, where to buy them, and encourage their use. It is unclear in which countries these apps are being downloaded, or whether app stores play a role in promoting or regulating these apps, particularly those that appear to target children. The lifetime popularity of 107 pro-smoking apps was investigated, using a third-party app metrics service that aggregates data from app stores about app download popularity by country. Apps were deemed popular if at any time in their lifespan they achieved a top 25 ranking overall across all apps, or a top 25 ranking in any particular category of apps, such as 'educational games'. Fifty-eight pro-smoking apps reached 'popularity' status in Apple and Android stores in one or more of 49 countries, particularly Italy, Egypt, Germany, Belgium and the USA. The daily downloads in each country ranged from approximately 2000 to 80 000. The Apple store featured five of the pro-smoking apps in various categories, and two apps were featured by the Android market. Two pro-smoking apps in the Apple store were extremely popular in the 'Educational Games' and 'Kids' Games' categories. Pro-smoking apps were popular in many countries. Most apps were assigned to entertainment and games categories, with some apps specifically targeting children through placement in categories directed at children. App stores that feature pro-smoking apps may be in violation of tobacco control laws. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. mHealth in Urology: A Review of Experts' Involvement in App Development.

    Directory of Open Access Journals (Sweden)

    Nuno Pereira-Azevedo

    Full Text Available Smartphones are increasingly playing a role in healthcare and previous studies assessing medical applications (apps have raised concerns about lack of expert involvement and low content accuracy. However, there are no such studies in Urology. We reviewed Urology apps with the aim of assessing the level of participation of healthcare professionals (HCP and scientific Urology associations in their development.A systematic search was performed on PubMed, Apple's App Store and Google's Play Store, for Urology apps, available in English. Apps were reviewed by three graders to determine the app's platform, target customer, developer, app type, app category, price and the participation of a HCP or a scientific Urology association in the development.The search yielded 372 apps, of which 150 were specific for Urology. A fifth of all apps had no HCP involvement (20.7% and only a third had been developed with a scientific Urology association (34.7%. The lowest percentage of HCP (13.4% and urological association (1.9% involvement was in apps designed for the general population. Furthermore, there was no contribution from an Urology society in "Electronic Medical Record" nor in "Patient Information" apps. A limitation of the study is that only Android and iOS apps were reviewed.Despite the increasing Mobile Health (mHealth market, this is the first study that demonstrates the lack of expert participation in the design of Urology apps, particularly in apps designed for the general public. Until clear regulation is enforced, the urological community should help regulate app development. Maintaining a register of certified apps or issuing an official scientific seal of approval could improve overall app quality. We propose that urologists become stakeholders in mHealth, shaping future app design and promoting peer-review app validation.

  16. The AppScale Cloud Platform: Enabling Portable, Scalable Web Application Deployment.

    Science.gov (United States)

    Krintz, Chandra

    2013-03-01

    AppScale is an open source distributed software system that implements a cloud platform as a service (PaaS). AppScale makes cloud applications easy to deploy and scale over disparate cloud fabrics, implementing a set of APIs and architecture that also makes apps portable across the services they employ. AppScale is API-compatible with Google App Engine (GAE) and thus executes GAE applications on-premise or over other cloud infrastructures, without modification.

  17. mHealth in Urology: A Review of Experts' Involvement in App Development.

    Science.gov (United States)

    Pereira-Azevedo, Nuno; Carrasquinho, Eduardo; Cardoso de Oliveira, Eduardo; Cavadas, Vitor; Osório, Luís; Fraga, Avelino; Castelo-Branco, Miguel; Roobol, Monique J

    2015-01-01

    Smartphones are increasingly playing a role in healthcare and previous studies assessing medical applications (apps) have raised concerns about lack of expert involvement and low content accuracy. However, there are no such studies in Urology. We reviewed Urology apps with the aim of assessing the level of participation of healthcare professionals (HCP) and scientific Urology associations in their development. A systematic search was performed on PubMed, Apple's App Store and Google's Play Store, for Urology apps, available in English. Apps were reviewed by three graders to determine the app's platform, target customer, developer, app type, app category, price and the participation of a HCP or a scientific Urology association in the development. The search yielded 372 apps, of which 150 were specific for Urology. A fifth of all apps had no HCP involvement (20.7%) and only a third had been developed with a scientific Urology association (34.7%). The lowest percentage of HCP (13.4%) and urological association (1.9%) involvement was in apps designed for the general population. Furthermore, there was no contribution from an Urology society in "Electronic Medical Record" nor in "Patient Information" apps. A limitation of the study is that only Android and iOS apps were reviewed. Despite the increasing Mobile Health (mHealth) market, this is the first study that demonstrates the lack of expert participation in the design of Urology apps, particularly in apps designed for the general public. Until clear regulation is enforced, the urological community should help regulate app development. Maintaining a register of certified apps or issuing an official scientific seal of approval could improve overall app quality. We propose that urologists become stakeholders in mHealth, shaping future app design and promoting peer-review app validation.

  18. An extra early mutant of pigeonpea

    International Nuclear Information System (INIS)

    Ravikesavan, R.; Kalaimagal, T.; Rathnaswamy, R.

    2001-01-01

    The redgram (Cajanus cajan (L.) Huth) variety 'Prabhat DT' was gamma irradiated with 100, 200, 300 and 400 Gy doses. Several mutants have been identified viz., extra early mutants, monostem mutants, obcordifoliate mutants and bi-stigmatic mutants. The extra early mutant was obtained when treated with 100 Gy dose. The mutant was selfed and forwarded from M 2 to M 4 generation. In the M 4 generation the mutant line was raised along with the parental variety. Normal cultural practices were followed and the biometrical observations were recorded. It was observed that for the characters viz., total number of branches per plant, number of pods per plants, seeds per pod, 100 seed weight and seed yield per plant there was no difference between the mutant and parent variety. Whereas, regarding the days to flowering and maturity the mutants were earlier than the parents. The observation was recorded from two hundred plants each. The mutant gives the same yield in 90 days as that of the parent variety in 107 days, which make it an economic mutant

  19. Problem-Solving Test: Tryptophan Operon Mutants

    Science.gov (United States)

    Szeberenyi, Jozsef

    2010-01-01

    This paper presents a problem-solving test that deals with the regulation of the "trp" operon of "Escherichia coli." Two mutants of this operon are described: in mutant A, the operator region of the operon carries a point mutation so that it is unable to carry out its function; mutant B expresses a "trp" repressor protein unable to bind…

  20. Sleep disturbances among Swedish soldiers after military service abroad

    OpenAIRE

    Pettersson, Karolina; Saers, Johannes; Lindberg, Eva; Janson, Christer

    2016-01-01

    Aims Since 1956, more than 100,000 Swedish soldiers have served abroad on various international missions. The aim of this paper was to determine whether there was a connection between military service abroad and sleep disorders among Swedish soldiers. Methods The prevalence of sleep disturbances among 1,080 veterans from Kosovo and Afghanistan was compared with almost 27,000 Swedes from a general population sample, using propensity score matching and logistic regression. The sleep disturbance...

  1. Doctrinal Imbalance: A Study of Swedish Army Doctrine

    Science.gov (United States)

    2014-06-13

    patience with endless grammar and spelling corrections. Furthermore, Dr. Sterrett also involved his wife, military historian Dr. Corinne Mahaffey, and his...provocative statement of the Swedish supreme commander. The Swedish Army teaches that doctrine derives from a balance between resources, national...it comes to writing a new doctrine, but none of them evaluates doctrine against a specific scenario using the actual forces the doctrine is supposed

  2. Gendered Resource Access and Utilisation in Swedish Family Farming

    OpenAIRE

    Andersson, Elias; Lidestav, Gun

    2014-01-01

    Gendered relations in resource access and farming are two important intersecting themes of gender studies in a northern rural context. However, conventional analysis and perceptions of the economy conceal the contribution of women within families, in businesses and in the labor market. This article demonstrate the significance of capital to farming women’s engagement with agriculture using a Swedish case study, based on descriptive analyses of data from the Federation of Swedish Farmers. To d...

  3. Analysis of Swedish consumers’ attitude to Chinese food

    OpenAIRE

    Chen, Jie

    2010-01-01

    The aim of this research is to find out what’s attitude Swedish consumers have to Chinese food. The questionnaires based on the Food Choice Questionnaire (FCQ) are handed out to 100 Swedish respondents in order to investigate their motivation on Chinese food choice. 78 questionnaires which were filled completely were selected for this study. Eleven factors involved in the questionnaire are labeled health, mood, convenience, sensory appeal, natural content, price, weight control, familiarity, ...

  4. The Analysis Of Smartphone Apps In Geomatics Education

    Science.gov (United States)

    Teo, T.-A.; Wu, H.-M.; Shih, T.-Y.; Tsai, F.

    2014-04-01

    Geomatics is a discipline of collecting, processing and analysing geospatial data. Data collection is a core process of geomatics which usually adopt precise equipment to measure geospatial data. With the development of technology, a smartphone in this present era is not simply for communication; several low cost measurement devices such as Global Positioning System (GPS), gyro and camera are assembled in a smartphone. Although the devices assembled in a smartphone could not meet the needs of accuracy requirement for many geomatics applications, millions of mobile applications (Apps) can be downloaded and installed from Google Play and Apple Store freely, and a variety of sensors can be chosen for user. Considering that the popularity and convenience of a smartphone, and assuming that the accuracy of those collected data is acceptable for learning purposes, it is expected that a smartphone can be employed in geomatics for hand-on education. For example, Vespucci OSM Editor is an App to edit the OpenStreetMap on Android. The user may have the hand-on experience on GPS positioning, web services and mapping via Vespucci OSM Editor. The aim of this paper is to collect and analyze different Apps for geomatics education. The Apps are classified into four categories, namely, surveying, remote sensing, GPS and Geographic Information System (GIS). In this paper, more than 20 free Apps are collected and analysed for different hand-on studies in geomatics education. Finally, all the related Apps are listed on a website for updating.

  5. A Smartphone App for Increasing Live Organ Donation.

    Science.gov (United States)

    Kumar, K; King, E A; Muzaale, A D; Konel, J M; Bramstedt, K A; Massie, A B; Segev, D L; Cameron, A M

    2016-12-01

    The incidence of live donor transplantation has declined over the past decade, and waitlisted candidates report substantial barriers to identifying a live donor. Since asking someone to donate feels awkward and unfamiliar, candidates are hesitant to ask directly and may be more comfortable with a passive approach. In collaboration with Facebook leadership (Facebook Inc., Menlo Park, CA), we developed a mobile application-an app-that enables waitlisted candidates to create a Facebook post about their experience with organ failure and their need for a live donor. We conducted a single-center prospective cohort study of 54 adult kidney-only and liver-only waitlisted candidates using the Facebook app. Cox proportional hazards models were used to describe donor referral on behalf of candidates using the app compared with matched controls. The majority of candidates who used the app reported it to be "good" or "excellent" with regard to the installation process (82.9%), readability (88.6%), simplicity (70.6%), clarity (87.5%) and the information provided (85.3%). Compared with controls, candidates using the Facebook app were 2.43 6.61 17.98 times more likely to have a donor come forward on their behalf (p Facebook app is an easy-to-use instrument that enables waitlisted candidates to passively communicate with their social network about their need for a live donor. © Copyright 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

  6. ReadyVax: A new mobile vaccine information app.

    Science.gov (United States)

    Bednarczyk, Robert A; Frew, Paula M; Salmon, Daniel A; Whitney, Ellen; Omer, Saad B

    2017-05-04

    Vaccine information of varying quality is available through many different sources. We describe the creation, release and utilization of ReadyVax, a new mobile smartphone app providing access to trustworthy, evidence-based vaccine information for a target audience of healthcare providers, pharmacists, and patients (including parents of children). We describe the information content and technical development of ReadyVax. Between the hard launch of the app on February 12, 2015 and October 8, 2016, the app has been downloaded by 5,142 unique users, with 6,841 total app sessions initiated, comprising a total of 15,491 screen views (2.3 screens/session on average). ReadyVax has been downloaded by users in 102 different countries; most users (52%) are from the United States. We are continuing outreach efforts to increase app use, and planning for development of an Android-compatible version of ReadyVax, to increase the available market for the app.

  7. Melanoma detection using a mobile phone app

    Science.gov (United States)

    Diniz, Luciano E.; Ennser, K.

    2016-03-01

    Mobile phones have had their processing power greatly increased since their invention a few decades ago. As a direct result of Moore's Law, this improvement has made available several applications that were impossible before. The aim of this project is to develop a mobile phone app, integrated with its camera coupled to an amplifying lens, to help distinguish melanoma. The proposed device has the capability of processing skin mole images and suggesting, using a score system, if it is a case of melanoma or not. This score system is based on the ABCDE signs of melanoma, and takes into account the area, the perimeter and the colors present in the nevus. It was calibrated and tested using images from the PH2 Dermoscopic Image Database from Pedro Hispano Hospital. The results show that the system created can be useful, with an accuracy of up to 100% for malign cases and 80% for benign cases (including common and atypical moles), when used in the test group.

  8. Biochemical and structural analysis of a site directed mutant of manganese dependent aminopeptidase P from Streptomyces lavendulae

    Directory of Open Access Journals (Sweden)

    ARYA NANDAN

    2015-08-01

    Full Text Available Aminopeptidase P (APP removes N-terminal amino acids from peptides and proteins when the penultimate residue is proline. To understand the structure-function relationships of aminopeptidase P of Streptomyces lavendulae, a conserved arginine residue was replaced with lysine (R453K by site-directed mutagenesis. The overexpressed wild and mutant enzymes were of nearly 60 kDa and purified by nickel affinity chromatography. Kinetic analysis of R453K variant using Gly-Pro-pNA as the substrate revealed an increase in Km with a decrease in Vmax, leading to overall decrease in the catalytic efficiency, indicating that the guanidinium group of arginine plays an important role in substrate binding in APP. We constructed three dimensional models for the catalytic domains of wild and mutant enzyme and it revealed an interaction in R453 of native enzyme through hydrogen bonding with the adjacent residues making a substrate binding cavity whereas K453 did not participate in any hydrogen bonding. Hence, R453 in APP of S. lavenduale must be playing a critical role in the hydrolysis of the substrate.

  9. APP-BP1 inhibits Aβ42 levels by interacting with Presenilin-1

    Directory of Open Access Journals (Sweden)

    Neve Rachael L

    2007-02-01

    Full Text Available Abstract Background The β-amyloid precursor protein (APP is sequentially cleaved by the β- and then γ-secretase to generate the amyloid β-peptides Aβ40 and Aβ42. Increased Aβ42/Aβ40 ratios trigger amyloid plaque formations in Alzheimer's disease (AD. APP binds to APP-BP1, but the biological consequence is not well understood. Results We report that when the endogenous APP-BP1 was suppressed by small interfering RNAs (siRNAs, cell-associated Aβ42 was dramatically increased in APP695 expressing primary neurons. The accumulation of Aβ42 was accompanied by significant increases in APP and APP-CTF in APP-BP1 siRNA expressing neurons. In contrast, APP-BP1 overexpression in primary neurons significantly decreased the levels of Aβ and endogenous APP but not APLPs. We also investigated the potential mechanism of APP-BP1-mediated APP processing. APP-BP1 co-precipitated with Presenilin-1 (PS1 in native rat brain extracts, co-migrated with the γ-secretase components in brain membrane extracts in glycerol gradient centrifugation, and colocalized in primary neurons. Further, the endogenous PS1-CTF was significantly downregulated by APP-BP1 expression. Conclusion Our data suggest that APP-BP1 may inhibit Aβ42 production by interacting with PS1 under physiological conditions.

  10. Free smoking cessation mobile apps available in Australia: a quality review and content analysis.

    Science.gov (United States)

    Thornton, Louise; Quinn, Catherine; Birrell, Louise; Guillaumier, Ashleigh; Shaw, Brad; Forbes, Erin; Deady, Mark; Kay-Lambkin, Frances

    2017-12-01

    This review aimed to identify free, high-quality, smoking cessation mobile applications (apps) that adhere to Australian smoking cessation treatment guidelines. A systematic search of smoking cessation apps was conducted using Google. The technical quality of relevant apps was rated using the Mobile Application Rating Scale. The content of apps identified as high quality was assessed for adherence to smoking cessation treatment guidelines. 112 relevant apps were identified. The majority were of poor technical quality and only six 'high-quality' apps were identified. These apps adhered to Australian treatment guidelines in part. The efficacy of two apps had been previously evaluated. In lieu of more substantial research in this area, it is suggested that the high-quality apps identified in this review may be more likely than other available apps to encourage smoking cessation. Implications for public health: Smoking cessation apps have the potential to address many barriers that prevent smoking cessation support being provided; however few high-quality smoking cessation apps are currently available in Australia, very few have been evaluated and the app market is extremely volatile. More research to evaluate smoking cessation apps, and sustained funding for evidence-based apps, is needed. © 2017 The Authors.

  11. Subcontractors and Component Suppliers in the Swedish Wind Power Industry

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Linn

    2003-05-01

    This paper studies the Swedish component suppliers in the wind power industry. This group has not received much attention so far, and today very little is known. This study addresses the fact that the Swedish component suppliers have not been able to penetrate the wind power market despite the Swedish industry's strength in mechanical and electrical engineering. The aims of this paper were to gather information regarding the existing production and to identify factors that affect the Swedish component suppliers' scope to penetrate the wind turbine market. To date, although Sweden has spent considerable amounts of money on projects involving wind turbines, there is no series production of large wind turbines in Sweden. The historical development of the wind turbine industry suggests this alone would have inhibited the development of component production in Sweden. Yet, the country's proximity and good access to large wind turbine producing countries should be an advantage. Various factors and issues are identified and discussed in this paper that are relevant for the Swedish component suppliers' scope to penetrate the wind turbine market. These include market and product development, buyer-supplier relationships, export and sourcing behaviors, and time of market entry. This is a first step towards increasing the knowledge of Swedish component production and it is recognized that more studies are required. Various areas where relevant knowledge is largely missing or scarce are identified and discussed as well, and should serve as relevant starting points for continued research.

  12. Subcontractors and Component Suppliers in the Swedish Wind Power Industry

    International Nuclear Information System (INIS)

    Takeuchi, Linn

    2003-05-01

    This paper studies the Swedish component suppliers in the wind power industry. This group has not received much attention so far, and today very little is known. This study addresses the fact that the Swedish component suppliers have not been able to penetrate the wind power market despite the Swedish industry's strength in mechanical and electrical engineering. The aims of this paper were to gather information regarding the existing production and to identify factors that affect the Swedish component suppliers' scope to penetrate the wind turbine market. To date, although Sweden has spent considerable amounts of money on projects involving wind turbines, there is no series production of large wind turbines in Sweden. The historical development of the wind turbine industry suggests this alone would have inhibited the development of component production in Sweden. Yet, the country's proximity and good access to large wind turbine producing countries should be an advantage. Various factors and issues are identified and discussed in this paper that are relevant for the Swedish component suppliers' scope to penetrate the wind turbine market. These include market and product development, buyer-supplier relationships, export and sourcing behaviors, and time of market entry. This is a first step towards increasing the knowledge of Swedish component production and it is recognized that more studies are required. Various areas where relevant knowledge is largely missing or scarce are identified and discussed as well, and should serve as relevant starting points for continued research

  13. Developing A mobile App for the Rehabilitation of Ankle Sprains

    Directory of Open Access Journals (Sweden)

    Suzanne McDonough

    2015-10-01

    Full Text Available Background: Musculoskeletal injuries are common and costly. Ankle sprains are one of the most common such injuries, carrying significant risk of persistent disabling symptoms. Rehabilitation has been shown to be more effective than standard conservative approaches for musculoskeletal injuries. The use of a mobile app to present rehabilitation guidance may offer a more accessible, engaging and effective solution to ankle sprain rehabilitation. Several existing apps target the prevention and rehabilitation of ankle sprains, however evaluation details are limited. Aim: To develop a mobile phone app that provides interactive, personalised and tailored rehabilitation for people following ankle sprains. Method(s: In order to build requirements and produce content for the app (entitled ReApp 2, relevant literature was reviewed and behaviour change strategies identified from the Behaviour Change Taxonomy (BCT developed by Michie et al (2013. A flexible and team orientated methodology called Agile was used to refine the technical specification and implemented software using feedback from technical experts (n=5 and clinicians (n=6. Technical experts consisted of participants with at least five years of experience in ICT or a related discipline. These technical experts completed the System Usability Scale (SUS to rate the usability of the software. The SUS is a widely used usability survey, which provides a single overall score for each participant. These scores can be used to provide comparison between user groups and other software. The clinicians consisted of five physiotherapists and one sport and exercise consultant, all of whom had at least five years of experience in providing rehabilitation treatment for ankle injuries. These clinicians also completed a questionnaire and gave qualitative feedback on the clinical appropriateness of the app. Results: The identified BCTs were prioritised according to clinical importance, technical complexity and time

  14. AppMovil conectada con AppServer. Prototipo de AppMovil para la gestión de un software MES

    OpenAIRE

    Rubio Martín, Carlos

    2015-01-01

    Se ha detectado que muchas empresas manufactureras utilizan un software para la gestión y seguimiento de la producción. Este software está disponible para los trabajadores en el lugar de trabajo, pero estos datos no son accesibles desde su casa o cuando realizan viajes al extranjero. A lo largo del proyecto se ha desarrollado una AppMovil que permite tener acceso a la gestión de la fabricación desde el teléfono móvil. Se ha programado un prototipo de AppMovil que permite al ...

  15. Consumer Mobile Apps for Potential Drug-Drug Interaction Check: Systematic Review and Content Analysis Using the Mobile App Rating Scale (MARS).

    Science.gov (United States)

    Kim, Ben Yb; Sharafoddini, Anis; Tran, Nam; Wen, Emily Y; Lee, Joon

    2018-03-28

    General consumers can now easily access drug information and quickly check for potential drug-drug interactions (PDDIs) through mobile health (mHealth) apps. With aging population in Canada, more people have chronic diseases and comorbidities leading to increasing numbers of medications. The use of mHealth apps for checking PDDIs can be helpful in ensuring patient safety and empowerment. The aim of this study was to review the characteristics and quality of publicly available mHealth apps that check for PDDIs. Apple App Store and Google Play were searched to identify apps with PDDI functionality. The apps' general and feature characteristics were extracted. The Mobile App Rating Scale (MARS) was used to assess the quality. A total of 23 apps were included for the review-12 from Apple App Store and 11 from Google Play. Only 5 of these were paid apps, with an average price of $7.19 CAD. The mean MARS score was 3.23 out of 5 (interquartile range 1.34). The mean MARS scores for the apps from Google Play and Apple App Store were not statistically different (P=.84). The information dimension was associated with the highest score (3.63), whereas the engagement dimension resulted in the lowest score (2.75). The total number of features per app, average rating, and price were significantly associated with the total MARS score. Some apps provided accurate and comprehensive information about potential adverse drug effects from PDDIs. Given the potentially severe consequences of incorrect drug information, there is a need for oversight to eliminate low quality and potentially harmful apps. Because managing PDDIs is complex in the absence of complete information, secondary features such as medication reminder, refill reminder, medication history tracking, and pill identification could help enhance the effectiveness of PDDI apps. ©Ben YB Kim, Anis Sharafoddini, Nam Tran, Emily Y Wen, Joon Lee. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 28.03.2018.

  16. Enhancers of Conidiation Mutants in Aspergillus Nidulans

    OpenAIRE

    Gems, D. H.; Clutterbuck, A. J.

    1994-01-01

    Mutants at a number of loci, designated sthenyo, have been isolated as enhancers of the oligoconidial mutations at the medA locus. Two loci have been mapped: sthA on linkage group I, and sthB on linkage group V. Two probable alleles have been identified at each locus but two further mutants were unlinked to either sthA or sthB. Neither sthA nor sthB mutants have conspicuous effects on morphology on their own, nor could the sthA1 sthB2 double mutant be distinguished from wild type. Mutants at ...

  17. Dwarf mutant of rice variety Seratus Malam

    International Nuclear Information System (INIS)

    Mugiono, P. S.; Soemanggono, A.M.R.

    1989-01-01

    Full text: Seeds of 'Seratus Malam', a local tall upland variety with long panicles and high yield potential were irradiated with 10-50 krad gamma rays in 1983. From 50,000 M 2 plants, 130 semidwarf mutants and 1 dwarf mutant were selected. The dwarf mutant M-362 was obtained from the 10 krad treatment. The mutant shows about 50% reduction in plant height, but also in number of productive tillers. Thus the yield per plant is also significantly less. However, the mutant gene is not allelic to DGWG and therefore may be useful in cross breeding. (author)

  18. Prevention of tick bites: an evaluation of a smartphone app.

    Science.gov (United States)

    Antonise-Kamp, L; Beaujean, D J M A; Crutzen, R; van Steenbergen, J E; Ruwaard, D

    2017-12-04

    Lyme borreliosis (LB) is the most common reported tick-borne infection in Europe, and involves transmission of Borrelia by ticks. As long as a vaccine is not available and effective measures for controlling tick populations are insufficient, LB control is focused on preventive measures to avoid tick bites. To inform citizens about the risk of ticks, motivate them to check for tick bites, and encourage them to remove any attached tick as quickly as possible, a mobile app called 'Tekenbeet' (Dutch for 'tick bite') was developed and released. The aim of this study was to evaluate the usage and user satisfaction of the 'Tekenbeet' app and to investigate whether it affects users' knowledge, perceived severity, perceived susceptibility, self-efficacy, response efficacy, current behavior and intention to comply with preventive measures. Usage of the app was evaluated with data obtained from Google Analytics. A survey among the Dutch general adult population with two data collection periods evaluated the usage, user satisfaction and its influence on abovementioned outcomes. Data obtained from Google Analytics showed the app was downloaded almost 40,000 in the 20 months following the launch. The 'tick radar' and 'tick diary' screens were viewed most often. In addition, a total of 554 respondents completed an online survey. The mean user satisfaction score was 7.44 (on a scale of 1-10) and 90.9% of respondents would recommend the app to others. On average, survey respondents who downloaded the app (n = 243) recorded significantly more often higher knowledge scores (OR 3.37; 95% CI 2.02-5.09) and had a higher intention to comply with preventive measures (OR 2.47; 95% CI 1.22-5.85) compared to respondents who did not download the app (n = 311). The 'Tekenbeet' app is a frequently used and well-appreciated educational tool to increase public knowledge of ticks and tick bites. It also helps to improve the user's intention to apply preventive measures. The use of

  19. Game Bola Tangkis Berbasis Android Menggunakan App Inventor

    Directory of Open Access Journals (Sweden)

    Mhd Arief Hasan

    2017-11-01

    Full Text Available AbstrakBerkembangnya teknologi yang berbasis mobile sekarang ini sudah sangat maju dan sering dipakai untuk dunia Information Technology (IT, bisnis, pendidikan dan media pembelajaran. Teknologi handphone yang saat ini berkembang pesat salah satunya adalah sistem operasi Android mobile (Android OS. Android adalah sistem operasi berbasis Linux yang dirancang untuk perangkat mobile layar sentuh yang memungkinkan perangkat lunak bebas dimodifikasi dan didistribusikan oleh pembuat perangkat, operator nirkabel dan pengembang aplikasi. Salah satu editor dalam pemrograman android adalah APP Inventor .App Inventor merupakan aplikasi web sumber terbuka yang awalnya dikembangkan oleh Google, dan saat ini dikelola oleh Massachusetts Institute of Technology (MIT. App Inventor memungkinkan pengguna baru untuk memprogram komputer untuk menciptakan aplikasi perangkat lunak bagi sistem operasi Android.  Dengan adanya kemudahan dalam pembuatan program yang disediakan oleh App Inventor yang tidak diharuskan lagi untuk menuliskan koding. Semua fasilitas itu bisa digunakan dengan menggunakan klik drag menggunakan blog diagram. Maka peneliti mengambil kasus game bola tangkis dalam penelitian ini. Kata kunci : Game Bola Tangkis, Android, App Inventor AbstractThe development of mobile-based technology is now very advanced and often used for the world of Information Technology (IT, business, education and learning media. Mobile technology is currently growing rapidly one of them is the Android mobile operating system (Android OS. Android is a Linux-based operating system designed for touch-screen mobile devices that allows free software to be modified and distributed by device makers, wireless carriers and app developers. One of the editors in android programming is APP Inventor. Appper Inventor is an open source web application originally developed by Google, and is currently managed by the Massachusetts Institute of Technology (MIT. App Inventor allows new users

  20. GABA(A receptor-mediated acceleration of aging-associated memory decline in APP/PS1 mice and its pharmacological treatment by picrotoxin.

    Directory of Open Access Journals (Sweden)

    Yuji Yoshiike

    Full Text Available Advanced age and mutations in the genes encoding amyloid precursor protein (APP and presenilin (PS1 are two serious risk factors for Alzheimer's disease (AD. Finding common pathogenic changes originating from these risks may lead to a new therapeutic strategy. We observed a decline in memory performance and reduction in hippocampal long-term potentiation (LTP in both mature adult (9-15 months transgenic APP/PS1 mice and old (19-25 months non-transgenic (nonTg mice. By contrast, in the presence of bicuculline, a GABA(A receptor antagonist, LTP in adult APP/PS1 mice and old nonTg mice was larger than that in adult nonTg mice. The increased LTP levels in bicuculline-treated slices suggested that GABA(A receptor-mediated inhibition in adult APP/PS1 and old nonTg mice was upregulated. Assuming that enhanced inhibition of LTP mediates memory decline in APP/PS1 mice, we rescued memory deficits in adult APP/PS1 mice by treating them with another GABA(A receptor antagonist, picrotoxin (PTX, at a non-epileptic dose for 10 days. Among the saline vehicle-treated groups, substantially higher levels of synaptic proteins such as GABA(A receptor alpha1 subunit, PSD95, and NR2B were observed in APP/PS1 mice than in nonTg control mice. This difference was insignificant among PTX-treated groups, suggesting that memory decline in APP/PS1 mice may result from changes in synaptic protein levels through homeostatic mechanisms. Several independent studies reported previously in aged rodents both an increased level of GABA(A receptor alpha1 subunit and improvement of cognitive functions by long term GABA(A receptor antagonist treatment. Therefore, reduced LTP linked to enhanced GABA(A receptor-mediated inhibition may be triggered by aging and may be accelerated by familial AD-linked gene products like Abeta and mutant PS1, leading to cognitive decline that is pharmacologically treatable at least at this stage of disease progression in mice.

  1. Navigating the App-Wilderness: Learn to Find the Best App or Start to Design One Yourself : Pre-Conference Session

    NARCIS (Netherlands)

    Kelders, Saskia; Bohlmeijer, Ernst

    2017-01-01

    In this workshop you will learn how to evaluate existing apps on their theoretical basis, their usability and their persuasiveness to keep users engaged. We will provide hands-on experience in evaluating and selecting the right app for the job; give examples of high quality and lower quality apps to

  2. Frameshifted beta-amyloid precursor protein (APP(+1)) is a secretory protein, and the level of APP(+1) in cerebrospinal fluid is linked to Alzheimer pathology

    NARCIS (Netherlands)

    Hol, Elly M.; van Dijk, Renske; Gerez, Lisya; Sluijs, Jacqueline A.; Hobo, Barbara; Tonk, Martijn T.; de Haan, Annett; Kamphorst, Wouter; Fischer, David F.; Benne, Rob; van Leeuwen, Fred W.

    2003-01-01

    Molecular misreading of the beta-amyloid precursor protein (APP) gene generates mRNA with dinucleotide deletions in GAGAG motifs. The resulting truncated and partly frameshifted APP protein ( APP(+1)) accumulates in the dystrophic neurites and the neurofibrillary tangles in the cortex and

  3. Interpolis SlimOpWeg-programma : de AutoModus-app : vragenlijstonderzoek naar het effect van een app om smartphonegebruik in de auto te verminderen.

    NARCIS (Netherlands)

    Groot-Mesken, J. de Wijnen, W. Stelling-Konczak, A. & Commandeur, J.J.F.

    2017-01-01

    Interpolis SlimOpWeg programme: the AutoModus app; Survey into the effect of an app on reducing smartphone use while driving a car. Within the programme SlimOpWeg the Dutch insurance company Interpolis had a smartphone app developed. The purpose of this ‘AutoModus app’ is to help young drivers to

  4. Users' Adoption of Mental Health Apps: Examining the Impact of Information Cues.

    Science.gov (United States)

    Huang, Hsiao-Ying; Bashir, Masooda

    2017-06-28

    Numerous mental health apps have been developed and made available to users on the current app market. Users may find it difficult and overwhelming to select apps from the hundreds of choices that are available in the app marketplace. Clarifying what information cues may impact a user's selection and adoption of mental health apps is now a critical and pressing issue. The aim of this study was to investigate the impact of information cues on users' adoption of anxiety apps using observational data from the Android app market. A systematic search of anxiety apps was conducted on the Android app store by using keywords search. The title and metadata information of a total of 274 apps that met our criteria were collected and analyzed. Three trained researchers recorded the app rankings from the search results page on different dates and Web browsers. Our results show that ratings (r=.56, Papp prices have significant negative correlations with installs (r=-.36). The results also reveal that lower-priced apps have higher ratings (r=-.23, Papp permission requests (r=.18, P=.002) from the device. For app titles, we found that apps with titles related to symptoms have significantly lower installs than apps with titles that are not related to symptoms (Papps by analyzing observational data. As the first of its kind, we found impactful indicators for mental health app adoptions. We also discovered a labeling effect of app titles that could hinder mental health app adoptions and which may provide insight for future designs of mental health apps and their search mechanisms. ©Hsiao-Ying Huang, Masooda Bashir. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 28.06.2017.

  5. mHealth in Urology: A Review of Experts’ Involvement in App Development

    Science.gov (United States)

    Pereira-Azevedo, Nuno; Carrasquinho, Eduardo; Cardoso de Oliveira, Eduardo; Cavadas, Vitor; Osório, Luís; Fraga, Avelino; Castelo-Branco, Miguel; Roobol, Monique J.

    2015-01-01

    Introduction Smartphones are increasingly playing a role in healthcare and previous studies assessing medical applications (apps) have raised concerns about lack of expert involvement and low content accuracy. However, there are no such studies in Urology. We reviewed Urology apps with the aim of assessing the level of participation of healthcare professionals (HCP) and scientific Urology associations in their development. Material and Methods A systematic search was performed on PubMed, Apple's App Store and Google's Play Store, for Urology apps, available in English. Apps were reviewed by three graders to determine the app’s platform, target customer, developer, app type, app category, price and the participation of a HCP or a scientific Urology association in the development. Results The search yielded 372 apps, of which 150 were specific for Urology. A fifth of all apps had no HCP involvement (20.7%) and only a third had been developed with a scientific Urology association (34.7%). The lowest percentage of HCP (13.4%) and urological association (1.9%) involvement was in apps designed for the general population. Furthermore, there was no contribution from an Urology society in "Electronic Medical Record" nor in "Patient Information" apps. A limitation of the study is that only Android and iOS apps were reviewed. Conclusions Despite the increasing Mobile Health (mHealth) market, this is the first study that demonstrates the lack of expert participation in the design of Urology apps, particularly in apps designed for the general public. Until clear regulation is enforced, the urological community should help regulate app development. Maintaining a register of certified apps or issuing an official scientific seal of approval could improve overall app quality. We propose that urologists become stakeholders in mHealth, shaping future app design and promoting peer-review app validation. PMID:25984916

  6. Genetic anticipation in Swedish Lynch syndrome families.

    Directory of Open Access Journals (Sweden)

    Jenny von Salomé

    2017-10-01

    Full Text Available Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies within families and genetic anticipation, i.e. decreasing age at onset in successive generations, has been suggested in LS. Anticipation is a well-known phenomenon in e.g neurodegenerative diseases and several reports have studied anticipation in heritable cancer. The purpose of this study is to determine whether anticipation can be shown in a nationwide cohort of Swedish LS families referred to the regional departments of clinical genetics in Lund, Stockholm, Linköping, Uppsala and Umeå between the years 1990-2013. We analyzed a homogenous group of mutation carriers, utilizing information from both affected and non-affected family members. In total, 239 families with a mismatch repair gene mutation (96 MLH1 families, 90 MSH2 families including one family with an EPCAM-MSH2 deletion, 39 MSH6 families, 12 PMS2 families, and 2 MLH1+PMS2 families comprising 1028 at-risk carriers were identified among the Swedish LS families, of which 1003 mutation carriers had available follow-up information and could be included in the study. Using a normal random effects model (NREM we estimate a 2.1 year decrease in age of diagnosis per generation. An alternative analysis using a mixed-effects Cox proportional hazards model (COX-R estimates a hazard ratio of exp(0.171, or about 1.19, for age of diagnosis between consecutive generations. LS-associated gene-specific anticipation effects are evident for MSH2 (2.6 years/generation for NREM and hazard ratio of 1.33 for COX-R and PMS2 (7.3 years/generation and hazard ratio of 1.86. The estimated anticipation effects for MLH1

  7. A Framework to Assist Health Professionals in Recommending High-Quality Apps for Supporting Chronic Disease Self-Management: Illustrative Assessment of Type 2 Diabetes Apps.

    Science.gov (United States)

    Hale, Kelli; Capra, Sandra; Bauer, Judith

    2015-09-14

    This paper presents an approach to assist health professionals in recommending high quality apps for supporting chronic disease self-management. Most app reviews focus on popularity, aesthetics, functionality, usability, and information quality. There is no doubt these factors are important in selecting trustworthy apps which are appealing to users, but behavioral theory may be also be useful in matching the apps to user needs. The framework developed aims to be methodologically sound, capable of selecting popular apps which include content covered by evidence-based programs, consistent with behavioral theory, as well as a patient-centered approach for matching apps to patients' individual needs. A single disease-type 2 diabetes-was selected to illustrate how the framework can be applied as this was deemed to represent the types of strategies used in many chronic diseases. A systematic approach based on behavioral theory and recommendations from best practice guidelines was developed for matching apps to patients' needs. In March 2014, a series of search strategies was used to identify top-rated iPhone and Android health apps, representing 29 topics from five categories of type 2 diabetes self-management strategies. The topics were chosen from published international guidelines for the management of diabetes. The senior author (KH) assessed the most popular apps found that addressed these topics using the Behavioral Theory Content Survey (BTS), which is based on traditional behavioral theory. A tool to assist decision making when using apps was developed and trialed with health professionals for ease of use and understanding. A total of 14 apps were assessed representing all five topic categories of self-management. Total theoretical scores (BTS scores) were less than 50 on a 100-point scale for all apps. Each app scored less than 50% of the total possible BTS score for all four behavioral theories and for most of the 20 behavioral strategies; however, apps scored

  8. Popular Nutrition-Related Mobile Apps: A Feature Assessment.

    Science.gov (United States)

    Franco, Rodrigo Zenun; Fallaize, Rosalind; Lovegrove, Julie A; Hwang, Faustina

    2016-08-01

    A key challenge in human nutrition is the assessment of usual food intake. This is of particular interest given recent proposals of eHealth personalized interventions. The adoption of mobile phones has created an opportunity for assessing and improving nutrient intake as they can be used for digitalizing dietary assessments and providing feedback. In the last few years, hundreds of nutrition-related mobile apps have been launched and installed by millions of users. This study aims to analyze the main features of the most popular nutrition apps and to compare their strategies and technologies for dietary assessment and user feedback. Apps were selected from the two largest online stores of the most popular mobile operating systems-the Google Play Store for Android and the iTunes App Store for iOS-based on popularity as measured by the number of installs and reviews. The keywords used in the search were as follows: calorie(s), diet, diet tracker, dietician, dietitian, eating, fit, fitness, food, food diary, food tracker, health, lose weight, nutrition, nutritionist, weight, weight loss, weight management, weight watcher, and ww calculator. The inclusion criteria were as follows: English language, minimum number of installs (1 million for Google Play Store) or reviews (7500 for iTunes App Store), relation to nutrition (ie, diet monitoring or recommendation), and independence from any device (eg, wearable) or subscription. A total of 13 apps were classified as popular for inclusion in the analysis. Nine apps offered prospective recording of food intake using a food diary feature. Food selection was available via text search or barcode scanner technologies. Portion size selection was only textual (ie, without images or icons). All nine of these apps were also capable of collecting physical activity (PA) information using self-report, the global positioning system (GPS), or wearable integrations. Their outputs focused predominantly on energy balance between dietary

  9. IDEAS and App Development Internship in Hardware and Software Design

    Science.gov (United States)

    Alrayes, Rabab D.

    2016-01-01

    In this report, I will discuss the tasks and projects I have completed while working as an electrical engineering intern during the spring semester of 2016 at NASA Kennedy Space Center. In the field of software development, I completed tasks for the G-O Caching Mobile App and the Asbestos Management Information System (AMIS) Web App. The G-O Caching Mobile App was written in HTML, CSS, and JavaScript on the Cordova framework, while the AMIS Web App is written in HTML, CSS, JavaScript, and C# on the AngularJS framework. My goals and objectives on these two projects were to produce an app with an eye-catching and intuitive User Interface (UI), which will attract more employees to participate; to produce a fully-tested, fully functional app which supports workforce engagement and exploration; to produce a fully-tested, fully functional web app that assists technicians working in asbestos management. I also worked in hardware development on the Integrated Display and Environmental Awareness System (IDEAS) wearable technology project. My tasks on this project were focused in PCB design and camera integration. My goals and objectives for this project were to successfully integrate fully functioning custom hardware extenders on the wearable technology headset to minimize the size of hardware on the smart glasses headset for maximum user comfort; to successfully integrate fully functioning camera onto the headset. By the end of this semester, I was able to successfully develop four extender boards to minimize hardware on the headset, and assisted in integrating a fully-functioning camera into the system.

  10. How Dangerous Are Your Smartphones? App Usage Recommendation with Privacy Preserving

    Directory of Open Access Journals (Sweden)

    Konglin Zhu

    2016-01-01

    Full Text Available With the rapid proliferation of mobile devices, explosive mobile applications (apps are developed in the past few years. However, the functions of mobile apps are varied and the designs of them are not well understood by end users, especially the activities and functions related to user privacy. Therefore, understanding how much danger of mobile apps with respect to privacy violation to mobile users is becomes a critical issue when people use mobile devices. In this paper, we evaluate the mobile app privacy violation of mobile users by computing the danger coefficient. In order to help people reduce the privacy leakage, we combine both the user preference to mobile apps and the privacy risk of apps and propose a mobile app usage recommendation method named AppURank to recommend the secure apps with the same function as the “dangerous” one for people use. The evaluation results show that our recommendation can reduce the privacy leakage by 50%.

  11. Pro iOS Geo building apps with location based services

    CERN Document Server

    Andreucci, Giacomo

    2013-01-01

    Deepen your app development skills with Pro iOS Geo. This book shows you how to use geolocation-based tools to enhance the iOS apps you develop. Author Giacomo Andreucci describes different ways to integrate geo services, depending on the kind of app you're looking to develop: a web app, a hybrid app, or a native app. You'll discover how to use the Google Maps API features to integrate powerful geo capabilities in your apps with a little effort. You'll learn how to: Design geographic features for your apps while respecting usability criteria Design touristic geo apps Use HTML5 and the Google M

  12. The challenges of co-developing a behaviour change app that aimed to make physical activity a habit

    Directory of Open Access Journals (Sweden)

    Alice S Forster

    2016-01-01

    Developers of behaviour change apps must balance the demands of users that will make using the app a habit, while retaining the ingredients necessary for the app to achieve its purpose. Mixed methods provide a rich data set with which to base app development and greater confidence that the app will meet the needs of users in terms of social networking and privacy.

  13. The AppComposer Web application for school teachers: A platform for translating and adapting educational web applications

    NARCIS (Netherlands)

    Rodriguez-Gil, Luis; Orduna, Pablo; Bollen, Lars; Govaerts, Sten; Holzer, Adrian; Gillet, Dennis; Lopez-de-Ipina, Diego; Garcia-Zubia, Javier

    2015-01-01

    Developing educational apps that cover a wide range of learning contexts and languages is a challenging task. In this paper, we introduce the AppComposer Web app to address this issue. The AppComposer aims at empowering teachers to easily translate and adapt existing apps that fit their educational

  14. APP Homodimers Transduce an Amyloid-β-Mediated Increase in Release Probability at Excitatory Synapses

    Directory of Open Access Journals (Sweden)

    Hilla Fogel

    2014-06-01

    Full Text Available Accumulation of amyloid-β peptides (Aβ, the proteolytic products of the amyloid precursor protein (APP, induces a variety of synaptic dysfunctions ranging from hyperactivity to depression that are thought to cause cognitive decline in Alzheimer’s disease. While depression of synaptic transmission has been extensively studied, the mechanisms underlying synaptic hyperactivity remain unknown. Here, we show that Aβ40 monomers and dimers augment release probability through local fine-tuning of APP-APP interactions at excitatory hippocampal boutons. Aβ40 binds to the APP, increases the APP homodimer fraction at the plasma membrane, and promotes APP-APP interactions. The APP activation induces structural rearrangements in the APP/Gi/o-protein complex, boosting presynaptic calcium flux and vesicle release. The APP growth-factor-like domain (GFLD mediates APP-APP conformational changes and presynaptic enhancement. Thus, the APP homodimer constitutes a presynaptic receptor that transduces signal from Aβ40 to glutamate release. Excessive APP activation may initiate a positive feedback loop, contributing to hippocampal hyperactivity in Alzheimer’s disease.

  15. APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein, RAP

    Science.gov (United States)

    Billnitzer, Andrew J.; Barskaya, Irina; Yin, Cailing; Perez, Ruth G.

    2013-01-01

    Amyloid precursor protein (APP) and its secreted form, sAPP, contribute to the development of neurons in hippocampus, a brain region critical for learning and memory. Full-length APP binds the low-density lipoprotein receptor-related protein (LRP), which stimulates APP endocytosis. LRP also contributes to neurite growth. Furthermore, the receptor associated protein (RAP) binds LRP in a manner that blocks APP-LRP interactions. To elucidate APP contributions to neurite growth for full-length APP and sAPP, we cultured wild type (WT) and APP knockout (KO) neurons in sAPPα and/or RAP and measured neurite outgrowth at 1 day in vitro. Our data reveal that WT neurons had less axonal outgrowth including less axon branching. RAP treatment potentiated the inhibitory effects of APP. KO neurons had significantly more outgrowth and branching, especially in response to RAP, effects which were also associated with ERK2 activation. Our results affirm a major inhibitory role by full-length APP on all aspects of axonal and dendritic outgrowth, and show that RAP-LRP binding stimulated axon growth independently of APP. These findings support a major role for APP as an inhibitor of neurite growth and reveal novel signaling functions for LRP that may be disrupted by Alzheimer’s pathology or therapies aimed at APP processing. PMID:23061396

  16. Expert Involvement and Adherence to Medical Evidence in Medical Mobile Phone Apps: A Systematic Review.

    Science.gov (United States)

    Subhi, Yousif; Bube, Sarah Hjartbro; Rolskov Bojsen, Signe; Skou Thomsen, Ann Sofia; Konge, Lars

    2015-07-27

    Both clinicians and patients use medical mobile phone apps. Anyone can publish medical apps, which leads to contents with variable quality that may have a serious impact on human lives. We herein provide an overview of the prevalence of expert involvement in app development and whether or not app contents adhere to current medical evidence. To systematically review studies evaluating expert involvement or adherence of app content to medical evidence in medical mobile phone apps. We systematically searched 3 databases (PubMed, The Cochrane Library, and EMBASE), and included studies evaluating expert involvement or adherence of app content to medical evidence in medical mobile phone apps. Two authors performed data extraction independently. Qualitative analysis of the included studies was performed. Based on inclusion criteria, 52 studies were included in this review. These studies assessed a total of 6520 apps. Studies dealt with a variety of medical specialties and topics. As much as 28 studies assessed expert involvement, which was found in 9-67% of the assessed apps. Thirty studies (including 6 studies that also assessed expert involvement) assessed adherence of app content to current medical evidence. Thirteen studies found that 10-87% of the assessed apps adhered fully to the compared evidence (published studies, recommendations, and guidelines). Seventeen studies found that none of the assessed apps (n=2237) adhered fully to the compared evidence. Most medical mobile phone apps lack expert involvement and do not adhere to relevant medical evidence.

  17. Geosocial Networking App Use Among Men Who Have Sex With Men in Serious Romantic Relationships.

    Science.gov (United States)

    Macapagal, Kathryn; Coventry, Ryan; Puckett, Jae A; Phillips, Gregory; Mustanski, Brian

    2016-08-01

    Geosocial networking (GSN) mobile phone applications ("apps") are used frequently among men who have sex with men (MSM) to socialize and meet sexual partners. Though GSN apps are used by some MSM in partnered relationships, little is known about how the use of GSN apps among MSM in serious romantic relationships can influence couples' sexual and relationship health. MSM in serious relationships (N = 323; M age = 40 years) were recruited through a popular GSN app for MSM. Participants completed open-ended items regarding the costs and benefits of app use to their relationships, discussions of app use with their partners, and preferences for relationship education related to app use. Reported benefits of app use included improving sex and communication with one's primary partner and fulfilling unmet sexual needs. Although approximately half had not discussed app use with their partners, citing app use as a "non-issue," many cited various drawbacks to app use, including jealousy and being a distraction from the relationship. Few described sexual health concerns as a drawback to meeting partners through apps. Regarding relationship education preferences, most wanted help with general communication skills and how to express one's sexual needs to a partner. Although GSN app use can enhance relationships and sex among partnered MSM, unclear communication about app use may contribute to negative relationship outcomes and could prevent partners from having sexual needs met. Relationship and sexual health education programs for male couples should consider addressing social media and technology use in their curricula.

  18. PNRI mutant variety: Cordyline 'Afable'

    International Nuclear Information System (INIS)

    Aurigue, Fernando B.

    2012-01-01

    Cordyline 'Afable', registered by the Philippine Nuclear Research Institute as NSIC 2009 Or-83, is an induced mutant developed from Cordyline 'Kiwi' by treating stem cuttings with acute gamma radiation from a Cobalt-60 source. The new mutant is identical to Cordyline 'Kiwi' in growth habit but differs in foliage color, and exhibits field resistance to Phytophthora sp., a fungus that causes leaf blight and rot in Ti plants. Results of this mutation breeding experiment showed that leaf color was altered by gamma irradiation and resistance to fungal diseases was improved. It also demonstrated how mutations that occur in nature may be generated artificially. Propagation of cordyline 'Afable' is true-to-type by vegetative propagation methods, such as separation of suckers and offshoots, shoot tip cutting, and top cutting. Aside from landscaping material, terrarium or dish-garden plant, it is ideal as containerized plant for indoor and outdoor use. The leaves or shoots may be harvested as cut foliage for flower arrangements. (author)

  19. Swedish women's perceptions of and conformity to feminine norms.

    Science.gov (United States)

    Kling, Johanna; Holmqvist Gattario, Kristina; Frisén, Ann

    2017-06-01

    The relatively high gender equality in the Swedish society is likely to exert an influence on gender role construction. Hence, the present research aimed to investigate Swedish women's perceptions of and conformity to feminine norms. A mixed methods approach with two studies was used. In Study 1, young Swedish women's gender role conformity, as measured by the Conformity to Feminine Norms Inventory 45 (CFNI-45), was compared to the results from previously published studies in Canada, the United States, and Slovakia. Overall, Swedish women displayed less conformity than their foreign counterparts, with the largest difference on the subscale Sexual fidelity. In Study 2, focus group interviews with young Swedish women added a more complex picture of feminine norms in the Swedish society. For instance the results indicated that Swedish women, while living in a society with a strong gender equality discourse, are torn between the perceived need to invest in their appearances and the risk of being viewed as non-equal when doing so. In sum, despite the fact that traditional gender roles are less pronounced in Sweden, gender role conformity is still a pressing issue. Since attending to the potential roles of feminine norms in women's lives previously has been proposed to be useful in counseling and therapeutic work, the present research also offers valuable information for both researchers and practitioners. [Correction added on 5 May 2017, after first online publication in April 2017: An incorrect Abstract was inadvertently captured in the published article and has been corrected in this current version.]. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  20. Uranium production from low grade Swedish shale

    International Nuclear Information System (INIS)

    Carlsson, O.

    1977-01-01

    In view of the present nuclear programmes a steep increase in uranium demand is foreseen which will pose serious problems for the uranium industry. The annual additions to uranium ore reserves must almost triple within the next 15 years in order to support the required production rates. Although there are good prospects for the discovery of further conventional deposits of uranium there is a growing interest in low grade uranium deposits. Large quantities of uranium exist in black shales, phosphates, granites, sea water and other unconventional sources. There are however factors which limit the utilization of these low grade materials. These factors include the extraction costs, the environmental constrains on mining and milling of huge amounts of ore, the development of technologies for the beneficiation of uranium and, in the case of very low grade materials, the energy balance. The availability of by-product uranium is limited by the production rate of the main product. The limitations differ very much according to types of ores, mining and milling methods and the surroundings. As an illustration a description is given of the Swedish Ranstad uranium shale project, its potential, constraints and technical solutions

  1. Workplace Incivility in a Swedish Context

    Directory of Open Access Journals (Sweden)

    Eva Torkelson

    2016-06-01

    Full Text Available The present study investigated workplace incivility in a Swedish context. The first aim was to assess how common the phenomenon is and the second was to study which groups (gender, age, ethnicity, and power position are most targeted by workplace incivility and are more prone to act in an uncivil way. Additionally, the relationships between experienced and witnessed incivility and wellbeing as well as instigated incivility were investigated. An online survey was administered by SIFO (the national public opinion poll agency. The collected data consist of a stratified sample whose composition is identical to the working population in Sweden (N = 3001. The results show that almost three quarters of the respondents had been the target of coworker incivility and 52% of supervisor incivility at least one to two times in the past year. Of the respondents, 75% had witnessed coworkers and 58% witnessed a supervisor treating others in an uncivil way. Furthermore, 66% had instigated uncivil acts toward others. The results also show that female and younger employees are slightly more targeted by incivility from coworkers and younger employees and supervisors are slightly more prone to instigate incivility. Moreover, it was found that that experienced incivility was the strongest predictor of low well-being and that witnessed incivility was the strongest predictor of instigated incivility.

  2. Swedish Radiation Protection Institute: information activities

    International Nuclear Information System (INIS)

    Persson, Lars

    2000-01-01

    The purpose of SSI's Information and PR Service is to broaden public awareness of radiation and radiation risks as well as to fulfill other performance goals. SSI achieves this through its advisory, educational and informative activities. SSI publishes two external magazines, Stralskyddsnytt and SSI News. Stralskyddsnytt - which is available in Swedish only - has a circulation of 2,000 and is published four times a year. SSI News - which is in English - is published twice a year and has a circulation of about 1,800. Another important channel of communication is the web site (www.ssi.se). Taking advantage of PUSH technology, SSI also distributes, by e-mail, press releases and other important information on radiation to radiation protection professionals in Sweden. SSI continuously monitors news by subscribing to a press clipping service. SSI Training is a commercial unit within the Information and PR Service. A policy for mass media contacts exists as well as a policy for internal communication. SSI has a graphic profile. SSI has a specialized research library. (author)

  3. Personality disorders in a Swedish peacekeeping unit.

    Science.gov (United States)

    Michel, Per-Olof; Lundin, Tom; Larsson, Gerry

    2005-01-01

    There is a lack of knowledge about the incidence of personality disorders and their consequences among peacekeepers. Moreover, most studies are follow-up studies in which, if at all, personality traits are screened for after the soldiers have left their service abroad. The aim of this paper was to study personality disorders in a longitudinal perspective. The method used was to screen the personnel in a Swedish mechanized battalion serving in Bosnia from March until October 1996 on four occasions: before deployment, immediately after deployment, 6 months after deployment and 1 year after deployment. Serving in the battalion were 724 individuals of whom 516 took part in the survey. The screening instrument used was the DSM-IV and ICD-10 Personality Questionnaire (DIP-Q). The result shows that the rate of personality disorders were on the same level, or a little bit lower, than in the general population. Moreover, personality disorders were related to impaired general mental health and to reported traumatic experiences. Personality disorders also seemed to contribute to poor mental health 1 year after returning home from a mission abroad. The implications of these results for the future selection of peacekeepers are discussed.

  4. Swedish entrepreneurs' use of occupational health services.

    Science.gov (United States)

    Gunnarsson, Kristina; Andersson, Ing-Marie; Josephson, Malin

    2011-10-01

    Small-scale enterprises are less often covered by occupational health services and have insufficient awareness about health and risks in the work environment. This study investigated how Swedish entrepreneurs in small-scale enterprises use occupational health services. The study used a questionnaire sent in two waves, 5 years apart. At baseline, 496 entrepreneurs responded, and 251 participated 5 years later. The questionnaire included items about affiliation with and use of occupational health services, physical and psychosocial work environments, work environment management, sources of work environment information, and membership in professional networks. Only 3% of entrepreneurs without employees and 19% of entrepreneurs with employees were affiliated with an occupational health service. Entrepreneurs affiliated with occupational health services were more active in work environment management and gathering information about the work environment. The occupational health services most used were health examinations, health care, and ergonomic risk assessments. Affiliation with occupational health services was 6% at both measurements, 4% at baseline, and 10% 5 years later. 2011, SLACK Incorporated.

  5. Swedish radiation protection institute. Information activities

    International Nuclear Information System (INIS)

    Persson, Lars

    1999-01-01

    The purpose of SSI's information and PR Service is to broaden public awareness of radiation and radiation risks as well as to fulfil other performance goals. SSI achieves this through its advisory, educational and informative activities. SSI publishes two external magazines, Straalskyddsnytt and SSI News. Straalskyddsnytt - which is available in Swedish only - has a circulation of 2,400 and is published four times a year. SSI News - which is in English - is published twice a year and has a circulation of about 1,500. Another important channel of communication is the web site (www.ssi.se). Taking advantage of PUSH technology, SSi also distributes, by e-mail, press releases and other important information of radiation to radiation protection professionals in Sweden. SSI continuously monitors news by subscribing to a press clipping service. SSI Training is a commercial unit within the Information and PR Service. A policy for mass media contacts exists as well as a policy for internal communication. SSI has a graphic profile. SSI has a specialised research library. (au)

  6. Popular Nutrition-Related Mobile Apps: A Feature Assessment

    Science.gov (United States)

    Fallaize, Rosalind; Lovegrove, Julie A; Hwang, Faustina

    2016-01-01

    Background A key challenge in human nutrition is the assessment of usual food intake. This is of particular interest given recent proposals of eHealth personalized interventions. The adoption of mobile phones has created an opportunity for assessing and improving nutrient intake as they can be used for digitalizing dietary assessments and providing feedback. In the last few years, hundreds of nutrition-related mobile apps have been launched and installed by millions of users. Objective This study aims to analyze the main features of the most popular nutrition apps and to compare their strategies and technologies for dietary assessment and user feedback. Methods Apps were selected from the two largest online stores of the most popular mobile operating systems—the Google Play Store for Android and the iTunes App Store for iOS—based on popularity as measured by the number of installs and reviews. The keywords used in the search were as follows: calorie(s), diet, diet tracker, dietician, dietitian, eating, fit, fitness, food, food diary, food tracker, health, lose weight, nutrition, nutritionist, weight, weight loss, weight management, weight watcher, and ww calculator. The inclusion criteria were as follows: English language, minimum number of installs (1 million for Google Play Store) or reviews (7500 for iTunes App Store), relation to nutrition (ie, diet monitoring or recommendation), and independence from any device (eg, wearable) or subscription. Results A total of 13 apps were classified as popular for inclusion in the analysis. Nine apps offered prospective recording of food intake using a food diary feature. Food selection was available via text search or barcode scanner technologies. Portion size selection was only textual (ie, without images or icons). All nine of these apps were also capable of collecting physical activity (PA) information using self-report, the global positioning system (GPS), or wearable integrations. Their outputs focused

  7. Gamma ray induced mutants in Coleus

    International Nuclear Information System (INIS)

    Vasudevan, K.; Jos, J.S.

    1988-01-01

    The germplasm collection of Chinese potato (Coleus parviflorus Benth) contains almost no variation for yield contributing traits. The crop does not produce seeds. Treatment of underground tubers with 1 kR, 2 kR, 3 kR and 4 kR gamma rays resulted in 50 morphologically different mutants which are maintained as mutant clones. In the M 1 V 1 generation, suspected mutant sprouts, were carefully removed and grown separately. The most interesting mutant types are the following: (i) erect mutant with spoon shaped light green leaves, 30 cm long inflorescences against 20 cm in the control, cylindrical tubers measuring ca. 7.0 cm long and 3 cm girth against 4 cm and 2.5 cm in the control (ii) early mutants 1 and 2, one having less leaf serration, the other having light green small leaves and dwarf type (iii) fleshy leaf mutant, dark green, thick and smooth leaves. Control plants spread almost in 1 m 2 area and bear tubers from the nodes of branches. In the early mutants tuber formation is mainly restricted to the base of the plant, which makes harvest easier. The crop usually matures within 150 - 160 days, the early mutants are ready for harvest 100 days after planting. As the mutants are less spreading, the yield could be increased by closer spacing

  8. Developing Smartphone Apps for Education, Outreach, Science, and Engineering

    Science.gov (United States)

    Weatherwax, A. T.; Fitzsimmons, Z.; Czajkowski, J.; Breimer, E.; Hellman, S. B.; Hunter, S.; Dematteo, J.; Savery, T.; Melsert, K.; Sneeringer, J.

    2010-12-01

    The increased popularity of mobile phone apps provide scientists with a new avenue for sharing and distributing data and knowledge with colleagues, while also providing meaningful education and outreach products for consumption by the general public. Our initial development of iPhone and Android apps centered on the distribution of exciting auroral images taken at the South Pole for education and outreach purposes. These portable platforms, with limited resources when compared to computers, presented a unique set of design and implementation challenges that we will discuss in this presentation. For example, the design must account for limited memory; screen size; processing power; battery life; and potentially high data transport costs. Some of these unique requirements created an environment that enabled undergraduate and high-school students to participate in the creation of these apps. Additionally, during development it became apparent that these apps could also serve as data analysis and engineering tools. Our presentation will further discuss our plans to use apps not only for Education and Public Outreach, but for teaching, science and engineering.

  9. Interactivity in Educational Apps for Young children: A Multimodal Analysis

    Directory of Open Access Journals (Sweden)

    Alexandra H. Blitz-Raith

    2017-11-01

    Full Text Available Interactivity is an important indicator of an educational app's reception. Since most educational apps are multimodal, it justifies a methodological initiative to understand meaningful involvement of multimodality in enacting and even amplifying interactivity in an educational app. Yet research so far has largely concentrated on algorithm construct and user feedback rather than on multimodal interactions, especially from a social semiotics perspective. Drawing from social semiotics approaches, this article proposes a multimodal analytic framework to examine three layers of mode in engendering interaction; namely, multiplicity, function, and relationship. Using the analytic framework in an analysis of The Farm Adventure for Kids, a popular educational app for pre-school children, we found that still images are dominant proportionally and are central in the interactive process. We also found that tapping still images of animals on screen is the main action, with other screen actions deliberately excluded. Such findings suggest that aligning children’s cognitive and physical capabilities to the use of mode become the primary consideration in educational app design and that consistent attendance to this alignment in mobilizing modes significantly affect an educational app’s interactivity, and consequently its reception by young children

  10. Mobile apps for orthopedic surgeons: how useful are they?

    Directory of Open Access Journals (Sweden)

    Franko OI

    2015-05-01

    Full Text Available Orrin I Franko,1 John P Andrawis,2 Dayne T Mickelson31Department of Orthopedic Surgery, University of California, San Diego Medical Center, San Diego, CA, USA; 2Department of Orthopedic Surgery, Harbor-University of California, Los Angeles Medical Center, Torrance, CA, USA; 3Department of Orthopedic Surgery and Sports Medicine, University of Washington, Seattle, WA, USAAbstract: Smartphone apps have become an integral part of medical training and practice in the hospital and clinical setting. However, to ensure the safety of patient care, it remains imperative that physicians and physician-educators alike continue to monitor and recognize the strengths and limitations of these powerful tools. Orthopaedic surgeons have widely adopted the use of smartphones and tablets and consequently, a number of resources have emerged to assist orthopaedic trainees and providers in discovering and assessing the most appropriate apps for their practice. The purpose of this review article is to advise readers on how best to identify apps for orthopaedic surgeons, summarize the most popular and useful existing apps, present the current available data to support their use, and provide recommendations to the orthopaedic community regarding safe and responsible mobile technology use in clinical practice.Keywords: smartphone, tablet, mobile, apps

  11. Launching a Native App: Lessons Learned in Academic Libraries

    Directory of Open Access Journals (Sweden)

    Samantha Raddatz

    2014-01-01

    Full Text Available If your library has a website and your users have mobile devices, congratulations: you have a mobile user experience. But is that experience a good one for your users? Libraries seeking to offer good user experience on mobile devices have two choices: a responsive website, which scales the amount of content displayed up and down depending on screen size, and a native app, downloadable from platform marketplaces. Would a native app improve your mobile user experience? Is an app mutually exclusive to a responsive website? Why would you choose one over the other? Is there any reason to have both? Who will do this development? In academic libraries, effective user experience always starts from an institutional context and what that context makes possible. For that reason, the editors of Weave will not presume to tell you whether your mobile presence should take the form of a native app, a responsively designed website, or both. This is despite the fact that we generally believe that a well-designed responsive website will serve the mobile patrons. But that’s in a vacuum. Your library, ours, they don’t exist in a vacuum. We hope you’ll read the following five brief case studies, put together by April Siqueiros and Samantha Raddatz of Pratt SILS, of academic libraries that chose to develop a native app with your own institutional context in mind. How will you best serve your mobile users?

  12. Building cross-platform apps using Titanium, Alloy, and Appcelerator cloud services

    CERN Document Server

    Saunders, Aaron

    2014-01-01

    Skip Objective-C and Java to get your app to market faster, using the skills you already have Building Cross-Platform Apps using Titanium, Alloy, and Appcelerator Cloud Services shows you how to build cross-platform iOS and Android apps without learning Objective-C or Java. With detailed guidance given toward using the Titanium Mobile Platform and Appcelerator Cloud Services, you will quickly develop the skills to build real, native apps- not web apps-using existing HTML, CSS, and JavaScript know-how. This guide takes you step-by-step through the creation of a photo-sharing app that leverages

  13. Building Mobile Apps for Underrepresented Mental Health care Consumers: A Grounded Theory Approach.

    Science.gov (United States)

    Leung, Ricky; Hastings, Julia F; Keefe, Robert H; Brownstein-Evans, Carol; Chan, Keith T; Mullick, Rosemary

    2016-01-01

    Cell phone mobile application ("app") use has risen dramatically within the past several years. Many individuals access apps to address mental health issues. Unlike individuals from privileged backgrounds, individuals from oppressed backgrounds may rely on apps rather than costly mental health treatment. To date, very little research has been published evaluating mental health apps' effectiveness. This paper focuses on three methods through which grounded theory can facilitate app development and evaluation for people underrepresented in mental health care. Recommendations are made to advance mobile app technology that will help clinicians provide effective treatment, and consumers to realize positive treatment outcomes.

  14. Android arcade game app a real world project : case study approach

    CERN Document Server

    DiMarzio, Jerome

    2012-01-01

    Apress, the leading Android books publisher, continues to provide you with very hands-on, practical books for teaching and showing app developers how to build and design apps, including game apps, that can be built and deployed in the various Android app stores out there. Android Arcade Game App:  A Real World Project - Case Study Approach is no different in that it walks you through creating an arcade style Prison Break game app-top to bottom-for an Android smartphone or tablet.  This book teaches you the unique characteristics and challenges of creating an Arcade style game And it provides y

  15. User perspectives on mobile apps for anxiety and depression: a pilot quantitative and qualitative inquiry

    DEFF Research Database (Denmark)

    Kok, Robin; Huisman, Annemiek; Fazel, Khatera

    to rate their first positive and negative impressions of the apps. Additionally, 234 public free-text user reviews of the 4 apps were analysed to extract themes. User preferred free, feature-rich and low-text apps as an addition to face-to-face therapy. A strong wish for anonymous contact with fellow...... patients was expressed. Overall, reviews contained only limited useful information of effective components. 85% of app reviews were positive and negative reviews focused mainly on technical aspects rather than the content of the app. Interestingly, there was no association between the app ratings...

  16. Sharing mutants and experimental information prepublication using FgMutantDb (https://scabusa.org/FgMutantDb).

    Science.gov (United States)

    Baldwin, Thomas T; Basenko, Evelina; Harb, Omar; Brown, Neil A; Urban, Martin; Hammond-Kosack, Kim E; Bregitzer, Phil P

    2018-02-02

    There is no comprehensive storage for generated mutants of Fusarium graminearum or data associated with these mutants. Instead, researchers relied on several independent and non-integrated databases. FgMutantDb was designed as a simple spreadsheet that is accessible globally on the web that will function as a centralized source of information on F. graminearum mutants. FgMutantDb aids in the maintenance and sharing of mutants within a research community. It will serve also as a platform for disseminating prepublication results as well as negative results that often go unreported. Additionally, the highly curated information on mutants in FgMutantDb will be shared with other databases (FungiDB, Ensembl, PhytoPath, and PHI-base) through updating reports. Here we describe the creation and potential usefulness of FgMutantDb to the F. graminearum research community, and provide a tutorial on its use. This type of database could be easily emulated for other fungal species. Published by Elsevier Inc.

  17. Effects of growth hormone-releasing hormone on sleep and brain interstitial fluid amyloid-β in an APP transgenic mouse model.

    Science.gov (United States)

    Liao, Fan; Zhang, Tony J; Mahan, Thomas E; Jiang, Hong; Holtzman, David M

    2015-07-01

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by impairment of cognitive function, extracellular amyloid plaques, intracellular neurofibrillary tangles, and synaptic and neuronal loss. There is substantial evidence that the aggregation of amyloid β (Aβ) in the brain plays a key role in the pathogenesis of AD and that Aβ aggregation is a concentration dependent process. Recently, it was found that Aβ levels in the brain interstitial fluid (ISF) are regulated by the sleep-wake cycle in both humans and mice; ISF Aβ is higher during wakefulness and lower during sleep. Intracerebroventricular infusion of orexin increased wakefulness and ISF Aβ levels, and chronic sleep deprivation significantly increased Aβ plaque formation in amyloid precursor protein transgenic (APP) mice. Growth hormone-releasing hormone (GHRH) is a well-documented sleep regulatory substance which promotes non-rapid eye movement sleep. GHRHR(lit/lit) mice that lack functional GHRH receptor have shorter sleep duration and longer wakefulness during light periods. The current study was undertaken to determine whether manipulating sleep by interfering with GHRH signaling affects brain ISF Aβ levels in APPswe/PS1ΔE9 (PS1APP) transgenic mice that overexpress mutant forms of APP and PSEN1 that cause autosomal dominant AD. We found that intraperitoneal injection of GHRH at dark onset increased sleep and decreased ISF Aβ and that delivery of a GHRH antagonist via reverse-microdialysis suppressed sleep and increased ISF Aβ. The diurnal fluctuation of ISF Aβ in PS1APP/GHRHR(lit/lit) mice was significantly smaller than that in PS1APP/GHRHR(lit/+) mice. However despite decreased sleep in GHRHR deficient mice, this was not associated with an increase in Aβ accumulation later in life. One of several possibilities for the finding is the fact that GHRHR deficient mice have GHRH-dependent but sleep-independent factors which protect against Aβ deposition. Copyright © 2014

  18. Deregulation and internationalisation - impact on the Swedish nuclear industry

    International Nuclear Information System (INIS)

    Haukeland, Sverre R.

    2010-01-01

    The deregulation of the Swedish electricity market in 1996 was well known in advance, and the nuclear power plants in Sweden, as well as their main suppliers, made early preparations for a this new situation. In a study - performed by the author at Malardalen University in Sweden - it is concluded that the electricity industry, including the nuclear power plants, was fundamentally transformed in conjunction with market liberalisation. Two large foreign companies, E-on and Fortum, entered the Swedish market and became part-owners of the nuclear plants. After deregulation, the electricity market in Sweden is dominated by these two companies and the large national company Vattenfall. Similarly, Vattenfall has recently grown into an international energy company, acquiring generation capacity in Northern Europe outside of Sweden, including nuclear power plants in Germany. Restructuring of the nuclear industry on the supplier side started in the 1980's, when the Swedish company ASEA and BBC of Switzerland merged to become ABB. Several years later the Swedish nuclear plant supplier ABB-Atom became part of Westinghouse Electric Company, today owned by Toshiba. The Swedish experience thus confirms an international trend of mergers and consolidation in the nuclear industry. (authors)

  19. Pain assessment practices in Swedish and Norwegian neonatal care units.

    Science.gov (United States)

    Andersen, Randi Dovland; Munsters, Josanne M A; Vederhus, Bente Johanne; Gradin, Maria

    2017-12-28

    The use of measurement scales to assess pain in neonates is considered a prerequisite for effective management of pain, but these scales are still underutilised in clinical practice. The aim of this study was to describe and compare pain assessment practices including the use of pain measurement scales in Norwegian and Swedish neonatal care units. A unit survey investigating practices regarding pain assessment and the use of pain measurement scales was sent to all neonatal units in Sweden and Norway (n = 55). All Norwegian and 92% of Swedish units responded. A majority of the participating units (86.5%) assessed pain. Swedish units assessed and documented pain and used pain measurement scales more frequently than Norwegian units. The most frequently used scales were different versions of Astrid Lindgren's Pain Scale (ALPS) in Sweden and Echelle Douleur Inconfort Noveau-Ne (EDIN), ALPS and Premature Infant Pain Profile (PIPP) in Norway. Norwegian head nurses had more confidence in their pain assessment method and found the use of pain measurement scales more important than their Swedish colleagues. The persisting difference between Swedish and Norwegian units in pain assessment and the use of pain measurement scales are not easily explained. However, the reported increased availability and reported use of pain measurement scales in neonatal care units in both countries may be seen as a contribution towards better awareness and recognition of pain, better pain management and potentially less suffering for vulnerable neonates. © 2017 Nordic College of Caring Science.

  20. Comparing Danish and Swedish versions of PISA scientific literacy

    DEFF Research Database (Denmark)

    Serder, Malmø University, Margareta; Sørensen, Helene

    This paper presents a comparison between the Swedish, Danish, English, and French versions of three scientific literacy test-units from the released PISA items 2006. More specifically it compares how different words and concepts have been translated in the Swedish and Danish tests, compared to th...... with these three PISA units. In the paper we claim that in spite of detailed and strongly controlled methods for achieving translations of high standard used by the PISA, important and perhaps even decisive, differences between the four versions exist.......This paper presents a comparison between the Swedish, Danish, English, and French versions of three scientific literacy test-units from the released PISA items 2006. More specifically it compares how different words and concepts have been translated in the Swedish and Danish tests, compared...... to the English and French original versions. Differences that occur as a result of the translation process concerning words’ meaning are demonstrated. The possible consequences of such differences are exemplified by an excerpt from a situation in which Swedish 15-year-old students collaboratively worked...

  1. Deregulation and internationalisation - impact on the Swedish nuclear industry

    Energy Technology Data Exchange (ETDEWEB)

    Haukeland, Sverre R. [Swedish Nuclear Society, Vattenfall Research and Development, 162 89 Stockholm (Sweden)

    2010-07-01

    The deregulation of the Swedish electricity market in 1996 was well known in advance, and the nuclear power plants in Sweden, as well as their main suppliers, made early preparations for a this new situation. In a study - performed by the author at Malardalen University in Sweden - it is concluded that the electricity industry, including the nuclear power plants, was fundamentally transformed in conjunction with market liberalisation. Two large foreign companies, E-on and Fortum, entered the Swedish market and became part-owners of the nuclear plants. After deregulation, the electricity market in Sweden is dominated by these two companies and the large national company Vattenfall. Similarly, Vattenfall has recently grown into an international energy company, acquiring generation capacity in Northern Europe outside of Sweden, including nuclear power plants in Germany. Restructuring of the nuclear industry on the supplier side started in the 1980's, when the Swedish company ASEA and BBC of Switzerland merged to become ABB. Several years later the Swedish nuclear plant supplier ABB-Atom became part of Westinghouse Electric Company, today owned by Toshiba. The Swedish experience thus confirms an international trend of mergers and consolidation in the nuclear industry. (authors)

  2. Demonstration and Dialogue: Mediation in Swedish Nuclear Waste Management

    International Nuclear Information System (INIS)

    Elam, Mark; Lidberg, Maria; Soneryd, Linda; Sundqvist, Goeran

    2009-01-01

    This report analyses mediation and mediators in Swedish nuclear waste management. Mediation is about establishing agreement and building common knowledge. It is argued that demonstrations and dialogue are the two prominent approaches to mediation in Swedish nuclear waste management. Mediation through demonstration is about showing, displaying, and pointing out a path to safe disposal for inspection. It implies a strict division between demonstrator and audience. Mediation through dialogue on the other hand, is about collective acknowledgements of uncertainty and suspensions of judgement creating room for broader discussion. In Sweden, it is the Swedish Nuclear Fuel and Waste Management Co. (SKB) that is tasked with finding a method and a site for the final disposal of the nation's nuclear waste. Two different legislative frameworks cover this process. In accordance with the Act on Nuclear Activities, SKB is required to demonstrate the safety of its planned nuclear waste management system to the government, while in respect of the Swedish Environmental Code, they are obliged to organize consultations with the public. How SKB combines these requirements is the main question under investigation in this report in relation to materials deriving from three empirical settings: 1) SKB's safety analyses, 2) SKB's public consultation activities and 3) the 'dialogue projects', initiated by other actors than SKB broadening the public arena for discussion. In conclusion, an attempt is made to characterise the long- term interplay of demonstration and dialogue in Swedish nuclear waste management

  3. Mutants for plant height in hexaploid triticale

    International Nuclear Information System (INIS)

    Reddy, V.R.K.; Gupta, P.K.

    1988-01-01

    Full text: Four hexaploid triticale varieties namely Beagle, Coorong, TL 419 and Welsh were subjected to gamma rays (100 Gy, 200 Gy, 300 Gy) and to aqueous solution of EMS (0.5%, (8h, 12h, 16h). In all four varieties, three types of mutants for plant height were observed: Semidwarf - the mutant plants are 20-25 cm shorter than the shortest plant in the control. Dwarf - mutant plants grow up to 40-60 cm. Stunted - mutant plants grow up to 10-20 cm. The segregation pattern suggests that semidwarf mutants are quantitatively inherited, showing continuous segregation in M 3 , M 4 and M 5 , whereas dwarf and stunted are monogenic recessive. They showed true breeding in M 3 and later generations. The semi-dwarf, dwarf and stunted mutants can be used as initial material for development of new varieties with short straw and resistance to lodging. (author)

  4. There is an app for that! The current state of mobile applications (apps) for DSM-5 obsessive-compulsive disorder, posttraumatic stress disorder, anxiety and mood disorders.

    Science.gov (United States)

    Van Ameringen, Michael; Turna, Jasmine; Khalesi, Zahra; Pullia, Katrina; Patterson, Beth

    2017-06-01

    Mental health apps are viewed as a promising modality to extend the reach of mental health care beyond the clinic. They do so by providing a means of assessment, tracking, and treatment through a smartphone. Given that nearly 2/3 of the American population owns a smartphone, mental health apps offer the possibility of overcoming treatment barriers such as geographic location or financial barriers. Unfortunately, the excitement surrounding mental health apps may be premature as the current supporting literature regarding their efficacy is limited. The app marketplace is littered with apps claiming to treat or assess symptoms, but even those created by reputable organizations or those incorporating components of evidence-based treatments have not yet been validated in terms of their efficacy. This review aims to provide a comprehensive review of the current state of the mental health app literature by examining published reports of apps designed for DSM-5 anxiety and mood disorders, OCD, and PTSD. The breadth of apps reviewed includes those oriented around assessment, symptom tracking, and treatment as well as "multipurpose" apps, which incorporate several of these components. This review will also present some of the most popular mental health apps which may have clinical utility and could be prescribed to clients. While we discuss many potential benefits of mental health apps, we focus on a number of issues that the current state of the app literature presents. Overall there is a significant disconnect between app developers, the scientific community and health care, leaving the utility of existing apps questionable. © 2017 Wiley Periodicals, Inc.

  5. Topic Space: Rapid Prototyping a Mobile Augmented Reality Recommendation App

    Directory of Open Access Journals (Sweden)

    Jim Hahn

    2015-10-01

    Full Text Available With funding from an Institute of Museum and Library Services (IMLS Sparks! Ignition Grant, researchers from the University of Illinois Library designed and tested a mobile recommender app with augmented reality features. By embedding open source optical character recognition software into a “Topic Space” module, the augmented reality app can recognize call numbers on a book in the library and suggest relevant items that are not shelved nearby. Topic Space can also show users items that are normally shelved in the starting location but that are currently checked out. Using formative UX methods, grant staff shaped app interface and functionality through early user testing. This paper reports results of UX testing; a redesigned mobile interface, and provides considerations on the future development of personalized recommendation functionality.

  6. A Comprehensive Evaluation Rubric for Assessing Instructional Apps

    Directory of Open Access Journals (Sweden)

    Cheng-Yuan Lee

    2015-01-01

    Full Text Available There is a pressing need for an evaluation rubric that examines all aspects of educational apps designed for instructional purposes. In past decades, many rubrics have been developed for evaluating educational computer-based programs; however, rubrics designed for evaluating the instructional implications of educational apps are scarce. When an Internet search for existing rubrics was conducted, only two such rubrics were found, and the evaluation criteria used in those rubrics was not clearly linked to previously conducted research nor were their evaluative dimensions clearly defined. These shortcomings result in reviewers being unable to use those rubrics to provide teachers with a precise analysis of an educational app’s instructional potential. In response, this paper presents a comprehensive rubric with 24-evaluative dimensions tailored specifically to analyze the educational potential of instructional apps.

  7. Start App: a coding experience between primary and secondary school

    Directory of Open Access Journals (Sweden)

    Filippo Bruni

    2016-04-01

    Full Text Available The paper presents a coding experience in primary school (“Colozza” in Campobasso. Within the theoretical framework offered by computational thinking, using App Inventor, it was created a calculator for smartphone in the Android environment. High school students (from a technical secondary school guided the pupils in primary school, making an interesting form of cooperation between primary and secondary schools. Start App: una esperienza di coding tra scuola primaria e scuola secondariaIl contributo presenta una esperienza di coding nella scuola primaria dell’Istituto Comprensivo statale “Colozza” di Campobasso. All’interno della cornice teorica offerta dal pensiero computazionale, utilizzando App Inventor, è stata realizzata una calcolatrice per smartphone in ambiente Android. A guidare gli allievi della primaria sono stati gli studenti dell’Istituto Tecnico Industriale “Marconi” di Campobasso realizzando una interessante forma di collaborazione tra istituti scolastici di ordine diverso.

  8. Learning iPhone Programming From Xcode to App Store

    CERN Document Server

    Allan, Alasdair

    2010-01-01

    Get the hands-on experience you need to program for the iPhone and iPod Touch. With this easy-to-follow guide, you'll build several sample applications by learning how to use Xcode tools, the Objective-C programming language, and the core frameworks. Before you know it, you'll not only have the skills to develop your own apps, you'll know how to sail through the process of submitting apps to the iTunes App Store. Whether you're a developer new to Mac programming or an experienced Mac developer ready to tackle the iPhone and iPod Touch, Learning iPhone Programming will give you a head start o

  9. Gamma ray induced mutants in Colocasia

    International Nuclear Information System (INIS)

    Vasudevan, K.; Jos, J.S.

    1988-01-01

    Presented are selected treatments with 250 r, 500 r and 1000 r gamma rays Colocasia mutants with changes in morphological and yield characters. Results from a preliminary yield trial of four mutants with its control variety C 9 are presented. The mutant's characteristics are (i) erect and narrow leaf (ii) cup shaped leaf, dwarf, matures within 120 days against 180 days in control (iii) narrow and thicker leaves, colour of lamina chalky and pale green (iv) vigorous

  10. Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport

    Directory of Open Access Journals (Sweden)

    Martin Steuble

    2012-06-01

    Endocytosis of amyloid-β precursor protein (APP is thought to represent the major source of substrate for the production of the amyloidogenic Aβ peptide by the β-secretase BACE1. The irreversible nature of proteolytic cleavage implies the existence of an efficient replenishment route for APP from its sites of synthesis to the cell surface. We recently found that APP exits the trans-Golgi network in intimate association with calsyntenin-1, a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport. Here we characterized the function of calsyntenin-1 in neuronal APP transport using selective immunoisolation of intracellular trafficking organelles, immunocytochemistry, live-imaging, and RNAi. We found that APP is co-transported with calsyntenin-1 along axons to early endosomes in the central region of growth cones in carriers that exclude the α-secretase ADAM10. Intriguingly, calsyntenin-1/APP organelles contained BACE1, suggesting premature cleavage of APP along its anterograde path. However, we found that APP contained in calsyntenin-1/APP organelles was stable. We further analyzed vesicular trafficking of APP in cultured hippocampal neurons, in which calsyntenin-1 was reduced by RNAi. We found a markedly increased co-localization of APP and ADAM10 in axons and growth cones, along with increased proteolytic processing of APP and Aβ secretion in these neurons. This suggested that the reduced capacity for calsyntenin-1-dependent APP transport resulted in mis-sorting of APP into additional axonal carriers and, therefore, the premature encounter of unprotected APP with its ectodomain proteases. In combination, our results characterize calsyntenin-1/APP organelles as carriers for sheltered anterograde axonal transport of APP.

  11. Incorporation of Mobile Application (App) Measures Into the Diagnosis of Smartphone Addiction.

    Science.gov (United States)

    Lin, Yu-Hsuan; Lin, Po-Hsien; Chiang, Chih-Lin; Lee, Yang-Han; Yang, Cheryl C H; Kuo, Terry B J; Lin, Sheng-Hsuan

    2017-07-01

    Global smartphone expansion has brought about unprecedented addictive behaviors. The current diagnosis of smartphone addiction is based solely on information from clinical interview. This study aimed to incorporate application (app)-recorded data into psychiatric criteria for the diagnosis of smartphone addiction and to examine the predictive ability of the app-recorded data for the diagnosis of smartphone addiction. Smartphone use data of 79 college students were recorded by a newly developed app for 1 month between December 1, 2013, and May 31, 2014. For each participant, psychiatrists made a diagnosis for smartphone addiction based on 2 approaches: (1) only diagnostic interview (standard diagnosis) and (2) both diagnostic interview and app-recorded data (app-incorporated diagnosis). The app-incorporated diagnosis was further used to build app-incorporated diagnostic criteria. In addition, the app-recorded data were pooled as a score to predict smartphone addiction diagnosis. When app-incorporated diagnosis was used as a gold standard for 12 candidate criteria, 7 criteria showed significant accuracy (area under receiver operating characteristic curve [AUC] > 0.7) and were constructed as app-incorporated diagnostic criteria, which demonstrated remarkable accuracy (92.4%) for app-incorporated diagnosis. In addition, both frequency and duration of daily smartphone use significantly predicted app-incorporated diagnosis (AUC = 0.70 for frequency; AUC = 0.72 for duration). The combination of duration, frequency, and frequency trend for 1 month can accurately predict smartphone addiction diagnosis (AUC = 0.79 for app-incorporated diagnosis; AUC = 0.71 for standard diagnosis). The app-incorporated diagnosis, combining both psychiatric interview and app-recorded data, demonstrated substantial accuracy for smartphone addiction diagnosis. In addition, the app-recorded data performed as an accurate screening tool for app-incorporated diagnosis. © Copyright 2017 Physicians

  12. Size and sulfation are critical for the effect of heparin on APP processing and Aβ production.

    Science.gov (United States)

    Cui, Hao; Hung, Amos C; Freeman, Craig; Narkowicz, Christian; Jacobson, Glenn A; Small, David H

    2012-11-01

    Alzheimer's disease is associated with abnormal accumulation of Aβ, which is produced from the β-amyloid precursor protein (APP) by the β-site APP-cleaving enzyme (BACE1) and γ-secretase. Our previous studies showed that heparin can decrease APP processing by decreasing the levels of BACE1 and ADAM10. In this study, we examined the effects of glycosaminoglycans (GAGs) on APP processing and Aβ production with the aim of understanding the specificity of the effects. Various GAG analogs were incubated with primary cortical cells derived from APP (SW)Tg2576 mice and the level of APP, proteolytic products of APP and APP-cleavage enzymes were measured. The effect of GAGs on APP processing was both size- and sulfation-dependent. 6-O-Sulfation was important for the effect on APP processing as heparin lacking 6-O sulfate were less potent than native heparin. However, deletion of carboxyl groups on heparin had no significant effect on APP processing. Our studies suggest that there is structural specificity to the effect of GAGs on APP processing and that certain GAGs have a greater effect on Aβ production than others. This suggests that it might be possible to alter the structure of GAGs to achieve more specific inhibitors of APP processing that can cross the blood-brain barrier. © 2012 The Authors Journal of Neurochemistry © 2012 International Society for Neurochemistry.

  13. Assessment of properties of Swedish reactor waste

    International Nuclear Information System (INIS)

    Sjoeblom, R.; Aittola, J.P.; Broden, K.; Andersson, K.; Wingefors, S.

    1984-01-01

    Low- and intermediate-level reactor waste has been produced in Sweden for many years, but only recently have plans for its final disposal been presented. According to these plans the waste will be transported from the nuclear power stations and research facilities to a final repository in hard rock under the Baltic Sea. It is anticipated that a series of waste handling and disposal operations will be commenced within the next ten years. For realization of these operations the waste forms must fulfil certain, as yet not clearly defined, quality requirements. A programme is outlined for the identification and quantification of those properties which are of importance for the safe handling, transportation and intermediate storage of the waste. The programme includes the following steps: (1) Collection of data concerning existing plant inventories (waste), raw material, solidification processes, waste composition, etc.; (2) Categorization of the waste; within each category the properties should be similar and expected to fall within certain intervals; (3) Identification of those properties which are of interest for each category with respect to both normal and abnormal handling situations; (4) Development and evaluation of methods for sampling and testing important properties; (5) Survey of existing R and D and test data, together with supplementary investigations and measurements; (6) Assessment of the properties of relevance for each waste category. This work was initiated by the Swedish Nuclear Power Inspectorate in 1981 and is being performed in close cooperation with the nuclear power industry. The results will be used by the concerned parties as a basis for the definition and stipulation of quality requirements for the various categories of waste, and the confirmation and introduction of quality control and quality assurance procedures. (author)

  14. BPcontrol. A Mobile App to Monitor Hypertensive Patients.

    Science.gov (United States)

    Carrera, Adrian; Pifarré, Marc; Vilaplana, Jordi; Cuadrado, Josep; Solsona, Sara; Mateo, Jordi; Solsona, Francesc

    2016-12-07

    Hypertension or high blood pressure is on the rise. Not only does it affect the elderly but is also increasingly spreading to younger sectors of the population. Treating this condition involves exhaustive monitoring of patients. The current mobile health services can be improved to perform this task more effectively. To develop a useful, user-friendly, robust and efficient app, to monitor hypertensive patients and adapted to the particular requirements of hypertension. This work presents BPcontrol, an Android and iOS app that allows hypertensive patients to communicate with their health-care centers, thus facilitating monitoring and diagnosis. Usability, robustness and efficiency factors for BPcontrol were evaluated for different devices and operating systems (Android, iOS and system-aware). Furthermore, its features were compared with other similar apps in the literature. BPcontrol is robust and user-friendly. The respective start-up efficiency of the Android and iOS versions of BPcontrol were 2.4 and 8.8 times faster than a system-aware app. Similar values were obtained for the communication efficiency (7.25 and 11.75 times faster for the Android and iOS respectively). When comparing plotting performance, BPcontrol was on average 2.25 times faster in the Android case. Most of the apps in the literature have no communication with a server, thus making it impossible to compare their performance with BPcontrol. Its optimal design and the good behavior of its facilities make BPcontrol a very promising mobile app for monitoring hypertensive patients.

  15. An acute stroke evaluation app: a practice improvement project.

    Science.gov (United States)

    Rubin, Mark N; Fugate, Jennifer E; Barrett, Kevin M; Rabinstein, Alejandro A; Flemming, Kelly D

    2015-04-01

    A point-of-care workflow checklist in the form of an iOS (iPhone Operating System) app for use by stroke providers was introduced with the objective of standardizing acute stroke evaluation and documentation at 2 affiliated academic medical centers. Providers used the app in unselected, consecutive patients undergoing acute stroke evaluation in an emergency department or hospital setting between August 2012 and January 2013 and August 2013 and February 2014. Satisfaction surveys were prospectively collected pre- and postintervention from residents, staff neurologists, and clinical data specialists. Residents (20 preintervention and 16 postintervention), staff neurologists (6 pre and 5 post), and clinical data specialists (4 pre and 4 post) participated in this study. All 16 (100%) residents had increased satisfaction with their ability to perform an acute stroke evaluation postintervention but only 9 (56%) of 16 felt the app was more help than hindrance. Historical controls aligned with preintervention results. Staff neurologists conveyed increased satisfaction with resident presentations and decision making when compared to preintervention surveys. Stroke clinical data specialists estimated a 50% decrease in data abstraction when the app data were used in the clinical note. Concomitant effect on door-to-needle (DTN) time at 1 site, although not a primary study measure, was also evaluated. At that 1 center, the mean DTN time decreased by 16 minutes when compared to the corresponding months from the year prior. The point-of-care acute stroke workflow checklist app may assist trainees in presenting findings in a standardized manner and reduce data abstraction time. The app may help reduce DTN time, but this requires further study.

  16. WhatsApp for Teaching Pathology Postgraduates: A Pilot Study.

    Science.gov (United States)

    Goyal, Aditi; Tanveer, Nadeem; Sharma, Pooja

    2017-01-01

    Postgraduate students spend a sizeable proportion of their time on social media platforms such as WhatsApp and Facebook. This change in our social interaction needs to be accommodated in our teaching methods. To engage them and arouse their curiosity, WhatsApp is an ideal platform. Digital photography by cell phone cameras has made it possible to share cases and discuss them with students round the clock. The primary aim of the study was to develop sharing and discussion of images using WhatsApp. It also aimed at gathering feedback by means of a questionnaire from pathology residents about their views about the use of WhatsApp for teaching purpose. A WhatsApp group by the name "Pathology on the Go" was created with the authors of this study as group administrators and all junior and senior resident doctors (69) as members. The group was used to discuss interesting cases, quiz questions, and other pathology-related academic issues. At the end of 4 weeks, a questionnaire was distributed among the members, and feedback was sought regarding their experience in the group. Over a 4-week period, 16 cases were discussed with 647 posts. A total of 45 participants out of 69 were active participants, and they had an average of 14 posts over the 4-week period. Majority of the participants found the discussions very useful with minimal disruption of the daily routine. There is a need to incorporate Web 2.0 tools such as WhatsApp in our teaching methods to capture as much screen time of the students as possible.

  17. WhatsApp for teaching pathology postgraduates: a pilot study

    Directory of Open Access Journals (Sweden)

    Aditi Goyal

    2017-01-01

    Full Text Available Introduction: Postgraduate students spend a sizeable proportion of their time on social media platforms such as WhatsApp and Facebook. This change in our social interaction needs to be accommodated in our teaching methods. To engage them and arouse their curiosity, WhatsApp is an ideal platform. Digital photography by cell phone cameras has made it possible to share cases and discuss them with students round the clock. Objective: The primary aim of the study was to develop sharing and discussion of images using WhatsApp. It also aimed at gathering feedback by means of a questionnaire from pathology residents about their views about the use of WhatsApp for teaching purpose. Materials and Methods: A WhatsApp group by the name “Pathology on the Go” was created with the authors of this study as group administrators and all junior and senior resident doctors (69 as members. The group was used to discuss interesting cases, quiz questions, and other pathology-related academic issues. At the end of 4 weeks, a questionnaire was distributed among the members, and feedback was sought regarding their experience in the group. Results: Over a 4-week period, 16 cases were discussed with 647 posts. A total of 45 participants out of 69 were active participants, and they had an average of 14 posts over the 4-week period. Majority of the participants found the discussions very useful with minimal disruption of the daily routine. Conclusion: There is a need to incorporate Web 2.0 tools such as WhatsApp in our teaching methods to capture as much screen time of the students as possible.

  18. Realtime Space Weather Forecasts Via Android Phone App

    Science.gov (United States)

    Crowley, G.; Haacke, B.; Reynolds, A.

    2010-12-01

    For the past several years, ASTRA has run a first-principles global 3-D fully coupled thermosphere-ionosphere model in real-time for space weather applications. The model is the Thermosphere-Ionosphere Mesosphere Electrodynamics General Circulation Model (TIMEGCM). ASTRA also runs the Assimilative Mapping of Ionospheric Electrodynamics (AMIE) in real-time. Using AMIE to drive the high latitude inputs to the TIMEGCM produces high fidelity simulations of the global thermosphere and ionosphere. These simulations can be viewed on the Android Phone App developed by ASTRA. The SpaceWeather app for the Android operating system is free and can be downloaded from the Google Marketplace. We present the current status of realtime thermosphere-ionosphere space-weather forcasting and discuss the way forward. We explore some of the issues in maintaining real-time simulations with assimilative data feeds in a quasi-operational setting. We also discuss some of the challenges of presenting large amounts of data on a smartphone. The ASTRA SpaceWeather app includes the broadest and most unique range of space weather data yet to be found on a single smartphone app. This is a one-stop-shop for space weather and the only app where you can get access to ASTRA’s real-time predictions of the global thermosphere and ionosphere, high latitude convection and geomagnetic activity. Because of the phone's GPS capability, users can obtain location specific vertical profiles of electron density, temperature, and time-histories of various parameters from the models. The SpaceWeather app has over 9000 downloads, 30 reviews, and a following of active users. It is clear that real-time space weather on smartphones is here to stay, and must be included in planning for any transition to operational space-weather use.

  19. Best iPad Apps The Guide for Discriminating Downloaders

    CERN Document Server

    Meyers, Peter

    2010-01-01

    What really wows iPad fans is when their touchscreen does what's impossible on other gadgets: the finger-painting app that turns a cross-country flight into a moving art class, the mini music studio (two-dozen instruments strong, each with motion-induced warble effects), and the portable fireworks display that you sculpt by swiping. Problem is, with tens of thousands of apps available for your iPad, who knows what to download? You can try to sort through a gazillion customer reviews with a mix of 5- and 1-star ratings, but that's a head-hurting time-waster. The stakes are getting higher, too

  20. SOME ASPECTS OF USING GOOGLE APPS INTO HIGHER EDUCATIONAL INSTITUTION

    Directory of Open Access Journals (Sweden)

    V. Oleksyuk

    2013-03-01

    Full Text Available The article investigated the concept of information and educational space» and determined the aspects of integration of its services. The unified authentication is an important component of information and educational space. It can be based on LDAP-directory. This study presented the main advantages of using Google Apps in process of learning. We described the experience of the integration Google Apps into information and educational space of Department of Physics and Mathematics of Ternopil V. Hnatyuk National Pedagogical University.