WorldWideScience

Sample records for sw-846 3rd edition

  1. Introducing ZBrush 3rd Edition

    CERN Document Server

    Keller, Eric

    2012-01-01

    Learn ZBrush inside and out with this updated new edition Get totally comfortable sculpting in a digital environment with the latest edition of this bestselling beginner's guide to ZBrush. Fully updated for the newest version of the software, ZBrush 4R3, this book dispels any fears you might have about the difficulty of using ZBrush and soon has you creating realistic, cartoon, and organic models with flair. Learn all the essentials, as you complete fun tutorials on painting, meshes, organic scripting, hard surface sculpting, lighting, rendering, and more. Introduces you to ZBrush, the sculpt

  2. Veterinary Microbiology, 3rd Edition

    Science.gov (United States)

    Veterinary Microbiology, Third Edition is organized into four sections and begins with an updated and expanded introductory section on infectious disease pathogenesis, diagnosis and clinical management. The second section covers bacterial and fungal pathogens, and the third section describes viral d...

  3. Hazardous Waste Test Methods / SW-846

    Science.gov (United States)

    The Resource Conservation and Recovery Act Test Methods for Evaluating Solid Waste: Physical/Chemical Methods (SW-846) provide guidance to analytical scientists, enforcement officers and method developers across a variety of sectors.

  4. Building java programs (3rd edition)

    CERN Document Server

    Reges, Stuart

    2013-01-01

    Building Java Programs: A Back to Basics Approach, Third Edition, introduces novice programmers to basic constructs and common pitfalls by emphasizing the essentials of procedural programming, problem solving, and algorithmic reasoning. By using objects early to solve interesting problems and defining objects later in the course, Building Java Programs develops programming knowledge for a broad audience. NEW! This edition is available with MyProgrammingLab, an innovative online homework and assessment tool. Through the power of practice and immediate personalized feedback, MyProgrammingLab helps students fully grasp the logic, semantics, and syntax of programming. Note: If you are purchasing the standalone text or electronic version, MyProgrammingLab does not come automatically packaged with the text. To purchase MyProgrammingLab, please visit: myprogramminglab.com or you can purchase a package of the physical text + MyProgrammingLab by searching the Pearson Higher Education web site. MyProgrammi...

  5. Basic Information about How to Use SW-846

    Science.gov (United States)

    This page discusses the Test Methods for Evaluating Solid Waste: Physical/Chemical Methods compendium, or SW-846, which is the EPA’s official collection of methods for use in complying with the Resource Conservation and Recovery Act (RCRA) regulations.

  6. Pediatric Dentistry: A Clinical Approach, 3rd Edition

    DEFF Research Database (Denmark)

    Pediatric Dentistry: A Clinical Approach, Third Edition provides a uniquely clear, comprehensive, and clinical approach to the dental treatment of children and adolescents. •Offers systematic coverage of all clinical, scientific and social topics relating to pediatric dentistry •Thoroughly revised...

  7. Radar principles for the nonspecialist, 3rd edition

    CERN Document Server

    Toomay, John

    2004-01-01

    Radar Principles for the Non-specialist, Third Edition continues its popular tradition: to distill the very complex technology of radar into its fundamentals, tying them to the laws of nature on one end and to the most modern and complex systems on the other. It starts with electromagnetic propagation, describes a radar of the utmost simplicity, and derives the radar range equation from that simple radar. Once the range equation is available, the book attacks the meaning of each term in it, moving through antennas, detection and tracking, radar cross-section, waveforms andsignal proces

  8. Sport concussion assessment tool - 3rd edition - normative reference values for professional ice hockey players.

    Science.gov (United States)

    Hänninen, Timo; Tuominen, Markku; Parkkari, Jari; Vartiainen, Matti; Öhman, Juha; Iverson, Grant L; Luoto, Teemu M

    2016-08-01

    To determine normative reference values for the Sport Concussion Assessment Tool-3rd Edition (SCAT3) using a large sample of professional male ice hockey players. A descriptive cross-sectional study. Preseason baseline testing was administered individually to 304 professional male ice hockey players. The participants were aged between 16 and 40 with a mean (M) age of 25.3 years. Over 60% of the athletes reported previous concussion, almost 20% had been hospitalized or medically imaged following a head trauma. Of the players, 48% reported no symptoms. The symptom score median (Md) was 1.0 (M=1.5) and severity median was 1.0 (M=2.3). The median of the SAC score was 27.0 (M=27.0). The median of the M-BESS was 1.0 (M=2.0). The Tandem gait median was 10.9s (M=10.8s). The most common baseline symptom was neck pain (24%). Delayed recall was the most difficult component of the SAC (Md=4); only 24% performed it flawlessly. All athletes completed the double-leg stance of the M-BESS without errors, but there was performance variability in the tandem stance (Md=0, M=0.6, range=0-10) and single-leg stance (Md=1.0, M=1.4, range=0-10). Representative normative reference values for the SCAT3 among professional male ice hockey players are provided. Copyright © 2015 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  9. The Principal as Instructional Leader: A Practical Handbook. 3rd Edition

    Science.gov (United States)

    Zepeda, Sally J.

    2013-01-01

    In the updated third edition of this highly successful book, leadership expert, Sally Zepeda offers savvy advice to both new and seasoned principals and assistant principals. You get practical tools and strategies, along with real-world examples to help you improve teacher effectiveness and boost student achievement. This edition features valuable…

  10. Leadership in Organizations: Current issues and key trends (3rd edition)

    OpenAIRE

    2016-01-01

    This is the third edition of a popular text first published in 2004. The 14 chapters locate the leadership phenomenon in the wider social and economic context. As the title suggests the underlying emphasis is upon changes to the understanding of leadership with reference to trends and current issues.

  11. Specifications and Construction Methods for Asphalt Concrete and Other Plant-Mix Types, 3rd Edition.

    Science.gov (United States)

    Asphalt Inst., College Park, MD.

    The purpose of this publication is to assist engineers in the analysis, design and control of paving projects that use asphalt concrete and other asphalt plant-mixes. The scope of this new third edition has been enlarged, and changes necessitated by advances in asphalt technology have been incorporated. Chapters I and II and Appendices A and B…

  12. The Psychology of Music, Edited by Diana Deutsch, 3rd Edition: Review of Chapters 1 to 5

    Directory of Open Access Journals (Sweden)

    Ricieri Carlini Zorzal

    2017-04-01

    Full Text Available This paper provides a review of the first five chapters of the third edition of the book The Psychology of Music edited by Diana Deutsch, namely: 1 “The Perception of Musical Tones” by Andrew J. Oxenham; 2 “Musical Timbre Perception” by Stephen McAdams; 3 “Perception of Singing” by Johan Sundberg; 4 “Intervals and Scales” by William F. Thompson; and 5 “Absolute Pitch” by Diana Deutsch.

  13. Critical applications of SW 846 US EPA methods to evaluation of marine samples quality

    Directory of Open Access Journals (Sweden)

    Patrícia Ferreira Silvério

    2010-06-01

    Full Text Available Technical evaluation of analytical data is of extreme relevance considering it can be used for comparisons with environmental quality standards and decision-making as related to the management of disposal of dredged sediments and the evaluation of salt and brackish water quality in accordance with CONAMA 357/05 Resolution. It is, therefore, essential that the project manager discusses the environmental agency's technical requirements with the laboratory contracted for the follow-up of the analysis underway and even with a view to possible re-analysis when anomalous data are identified. The main technical requirements are: (1 method quantitation limits (QLs should fall below environmental standards; (2 analyses should be carried out in laboratories whose analytical scope is accredited by the National Institute of Metrology (INMETRO or qualified or accepted by a licensing agency; (3 chain of custody should be provided in order to ensure sample traceability; (4 control charts should be provided to prove method performance; (5 certified reference material analysis or, if that is not available, matrix spike analysis, should be undertaken and (6 chromatograms should be included in the analytical report. Within this context and with a view to helping environmental managers in analytical report evaluation, this work has as objectives the discussion of the limitations of the application of SW 846 US EPA methods to marine samples, the consequences of having data based on method detection limits (MDL and not sample quantitation limits (SQL, and present possible modifications of the principal method applied by laboratories in order to comply with environmental quality standards.Avaliação técnica do resultado analítico é de extrema relevância, pois o mesmo será utilizado para comparação com legislações e tomadas de decisão, tais como, disposição adequada de sedimento dragado e avaliação da qualidade de água superficial salobra e salina

  14. Psychometric properties and validation of Portuguese version of Ages & Stages Questionnaires (3rd edition): 9, 18 and 30 Questionnaires.

    Science.gov (United States)

    Lopes, Sónia; Graça, Patrícia; Teixeira, Salete; Serrano, Ana Maria; Squires, Jane

    2015-09-01

    The essential underlying foundations of Early Intervention (EI), in which parents/family play a critical role in their child's development, leads us to conclude that their contribution assessing early detection of problems is fundamental. The Ages & Stages Questionnaires (ASQ) is a standardized screening instrument that has been successfully studied in different countries and cultures. Translate and study the psychometrics proprieties of the Portuguese version of the 9, 18 and 30month questionnaires of the Ages and Stages Questionnaires, 3rd edition (ASQ-3). Cross-sectional study. Validity and reliability were studied in a sample of 234 parents of children within 9, 18 and 30months. The results indicated that the questionnaires had good internal consistency, strong agreement between observers and between observations with two weeks interval, and strong Pearson product-moment correlation coefficients between the overall and the total for each domain. The cutoff points (i.e. 2 standard deviations below the mean domain score), that identifies children who should receive further referral for more comprehensive assessment, were close to those determined in the original ASQ-3 psychometric studies. Cronbach's alpha ranging from .42 to .70 and Pearson's r values varies from .22 to .60. Although some weaknesses were noted in psychometric qualities analysis, it can be concluded that the ASQ-PT of 9, 18 and 30months of age fulfills the requirements of a screening tool validated for the Portuguese population. To allow the early identification of children with developmental problems. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  15. Star Ware: The Amateur Astronomer's Guide to Choosing, Buying, and Using Telescopes and Accessories, 3rd Edition

    Science.gov (United States)

    Harrington, Philip S.

    2002-05-01

    Praise for the Second Edition of Star Ware "Star Ware is still a tour de force that any experienced amateur will find invaluable, and which hardware-minded beginners will thoroughly enjoy." -Robert Burnham, Sky & Telescope magazine "Star Ware condenses between two covers what would normally take a telescope buyer many months to accumulate." -John Shibley, Astronomy magazine Now more than ever, the backyard astronomer has a dazzling array of choices when it comes to telescope shopping-which can make choosing just the right sky-watching equipment a formidable challenge. In this revised and updated edition of Star Ware, the essential guide to buying astronomical equipment, award-winning astronomy writer Philip Harrington does the work for you, analyzing and exploring today's astronomy market and offering point-by-point comparisons of everything you need. Whether you're an experienced amateur astronomer or just getting started, Star Ware, Third Edition will prepare you to explore the farthest reaches of space with: Extensive, expanded reviews of leading models and accessories, including dozens of new products, to help you buy smart A clear, step-by-step guide to all aspects of purchasing everything from telescopes and binoculars to filters, mounts, lenses, cameras, film, star charts, guides and references, and much more Eleven new do-it-yourself projects for making unique astronomical equipment at home Easy tips on maintenance, photography, and star-mapping to help you get the most out of your telescope Lists of where to find everything astronomical, including Internet sites and Web resources; distributors, dealers, and conventions; and corporate listings for products and services

  16. Metabolic engineering of E.coli for the production of a precursor to artemisinin, an anti-malarial drug [Chapter 25 in Manual of Industrial Microbiology and Biotechnology, 3rd edition

    Energy Technology Data Exchange (ETDEWEB)

    Petzold, Christopher; Keasling, Jay

    2011-07-18

    This document is Chapter 25 in the Manual of Industrial Microbiology and Biotechnology, 3rd edition. Topics covered include: Incorporation of Amorpha-4,11-Diene Biosynthetic Pathway into E. coli; Amorpha-4,11-Diene Pathway Optimization; "-Omics" Analyses for Increased Amorpha-4,11-Diene Production; Biosynthetic Oxidation of Amorpha-4,11-Diene.

  17. Selected Abstracts of the 3rd Edition of Transport of High Risk Infants; Oxford (UK; August 31st-September 2nd, 2017

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2017-08-01

    Full Text Available Selected Abstracts of the 3rd Edition of Transport of High Risk Infants; Oxford (UK; August 31st-September 2nd, 2017ABS 1. MORTALITY RATE IN 23-30 WEEKS PRE­MATURE BORN IN LEVEL 2 HOSPITAL IN COMPARISON TO THOSE BORN IN TERTIARY-CARE HOSPITAL • J.P. Doray, J.L. DorayABS 2. THE QUEBEC AEROMEDICAL EXPERIENCE: EVACUATION OF NEONATES FROM AREAS IN EXTREME WEATHER CONDITIONS – IN­NOVATIONS IN SAFETY AND EFFICIENCY • É. Notebaert, J. Provencher, R. Bernier, S. Côté, S. KindABS 3. NASAL HIGH FLOW SUPPORT DURING NEONATAL RETRIEVAL IN VICTORIA, AUSTRALIA • V. Abraham, C. Roberts, B. Manley, L. Owen, M. Stewart, P. DavisABS 4. NEONATAL TRANSPORT TO AND FROM A REGIONAL LEVEL 2 CENTRE • C. Moore, M. Cassidy, M. Byrne, A. Bowden, J. Franta, I. Farombi, J. FitzsimonsABS 5. PASSIVE THERAPEUTIC HYPOTHERMIA DURING AMBULANCE AND HELICOPTER SECONDARY NEONATAL TRANSPORT IN NEONATES WITH HYPOXIC BRAIN INJURY: 10-YEARS RETROSPECTIVE SURVEY • M. Leben, M. Nolimal, I. Vidmar, S. GrosekABS 6. STABILIZATION OF CRITICALLY ILL NEW­BORNS: PREVENTION OF ACUTE KIDNEY INJURY • A. Babintseva, Y. Hodovanets, L. AgafonovaABS 7. TRANSPORT OF THE SURGICAL NEONATES • R. Pejaver, A. Poveidein, D. Winterbank-Scott, C. Keys, N. GuptaABS 8. AUDIT OF VENTILATED NEONATAL TRANS­FERS IN NORTHERN IRELAND FROM 1ST JANUARY 2017 UNTIL 1ST MAY 2017 • R. Moore, S. KnoxABS 9. “HUB AND SPOKE” ECMO IN NEONATES WITH MECONIUM ASPIRATION SYNDROME: A PRELIMINARY REPORT • N. Doglioni, D. Fichera, F. Zanella, M. Padalino, V. Vida, G. Stellin, P. Lago, D. TrevisanutoABS 10. INTRA-HOSPITAL TRANSPORTATION OF EX­TREMELY PRETERM INFANTS AND INCI­DENCE OF INTRAVENTRICULAR HAEMOR­RHAGES • N. Wadström, M. Breindahl, B. Hallberg, B. SkiöldABS 11. RISK OF POSTNATAL TRANSPORT AND OUT­COME OF LATE PRETERM INFANTS BORN AT NON-TERTIARY CENTRES: A RETRO­SPEC­TIVE COHORT STUDY • N. Doglioni, L. Salmaso, P. Facchin, D. TrevisanutoABS 12. COMPARING THREE METHODS OF THERA

  18. 3rd annual biomass energy systems conference

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-01

    The main objectives of the 3rd Annual Biomass Energy Systems Conference were (1) to review the latest research findings in the clean fuels from biomass field, (2) to summarize the present engineering and economic status of Biomass Energy Systems, (3) to encourage interaction and information exchange among people working or interested in the field, and (4) to identify and discuss existing problems relating to ongoing research and explore opportunities for future research. Abstracts for each paper presented were edited separately. (DC)

  19. 3rd IDPASC School

    CERN Document Server

    Lectures on particle physics, astrophysics and cosmology

    2015-01-01

    This volume gathers the content of the courses held at the Third IDPASC School, which took place in San Martiño Pinario, Hospederia and Seminario Maior, in the city of Santiago de Compostela, Galiza, Spain, from January 21st to February 2nd, 2013. This school is the annual joint program of the International Doctorate Network in Particle Physics, Astrophysics, and Cosmology (IDPASC).   The purpose of the school series is to present doctoral students from different universities and laboratories in Europe and beyond with a broad range of the latest results and current state of the art in the fields of Particle Physics, Astrophysics, and Cosmology, and to further introduce them to both the questions now posed by the potentials of physics and to challenges connected with current and future experiments – in particular, with the newly available energy ranges.   Following these guidelines, the content of this third edition of the IDPASC School was jointly planned by the Academic Council and by the network’s In...

  20. Alaska Highway bibliography, 3rd edition

    DEFF Research Database (Denmark)

    Prange, Laurie

    land route to Alaska for defence purposes. The military was not interested in developing or planning a highway for the civilian needs of the future. The chosen route ran from Edmonton to Whitehorse, then on to Fairbanks. The U.S. Army and U.S. Public Roads Administration (PRA) roughed out a “pioneer...... increasing military needs. The unexpected bombing of Pearl Harbour in December 1941 stimulated interest in the construction of the Alaska Highway by the American government. The U.S. Army Corps of Engineers selected a route based on the location of the NWSR airfields and the military needs for an alternative....... Thus the Canol project was developed to ensure a continuing supply of petroleum to meet military needs. The end result of the Canol project was a pipeline and road network transporting oil from Norman Wells on the Mackenzie River, Northwest Territories, to Whitehorse, Watson Lake and Fairbanks...

  1. The Physics of Glaciers, 3rd Edition

    Science.gov (United States)

    Bahr, David

    At one time or another, who among us has not marveled at the beauty of the snow and ice-covered Alps, or admired the tenacity of polar explorers and the adventurous spirits of climbers on the glacier-clad summits of the high Himalaya? The fascination of distant ice covered expanses has enlisted more than a few recruits into the ranks of glaciologists, but many, if not most, of today's students of glaciology are a slightly less romantic and more mathematical lot, attracted by the quantitative world of physics and the applied sciences of polar climatology, ice mechanics, and snow hydrology.Once a relatively quiet branch of geophysics filled with venturesome climbers capable of reaching the objects of their study, glaciology is now a field that is fueled by a rapid influx of talent, technology, and new ideas due to the increasingly acknowledged relationships between global climate, sea level, and ice sheets. While the understanding of glacier processes has seen significant progress, as a result there is also a sense of being overwhelmed by the voluminous and sometimes speculative theories and field observations associated with an expanding discipline.

  2. Atlas of Electroencephalography, 3rd Edition.

    Science.gov (United States)

    Asadi-Pooya, Ali Akbar; Dlugos, Dennis; Skidmore, Christopher; Sperling, Michael R

    2017-09-01

    Electroencephalography (EEG) is the recording of the electrical activity of the brain. EEG is a reliable test to assess cerebral function. It aids in diagnosis, classification, and management of patients with epilepsy. It also has practical uses in conditions other than epilepsy. Moreover, it is harmless and inexpensive. EEG is an important tool for evaluating patients with epilepsy. It may help classify the syndrome, identify the likely source of focal seizures, and confirm a diagnosis of status epilepticus. EEG is therefore helpful when selecting appropriate antiepileptic drugs for patients with epilepsy, is valuable for diagnosis and management of status epilepticus as well as predicting the prognosis in epilepsy syndromes, and, is finally useful when localizing an area for resection in surgery candidates. In addition, despite advances in neuroimaging, EEG remains a valuable tool in the evaluation of stuporous and comatose patients. A systematic approach is essential for EEG interpretation, and when combined with good clinical judgment, it will improve diagnostic sensitivity and specificity and may improve therapeutic outcomes. This EEG atlas is designed as a practical guide for neurology residents, neurologists, and epileptologists, so that they may appropriately identify normal and abnormal findings, while reading an EEG. By reading and reviewing the relevant chapter of this well-organized atlas, that includes many EEG images, the reader will also learn how to report an EEG finding. We hope that this atlas fills an unmet need, and leads to improved patient care.

  3. Lecture Notes in Statistics. 3rd Semester

    DEFF Research Database (Denmark)

    The lecture note is prepared to meet the requirements of the curriculum for the 3rd smester course in statistics at the Aarhus School of Business.......The lecture note is prepared to meet the requirements of the curriculum for the 3rd smester course in statistics at the Aarhus School of Business....

  4. Exercises in Statistics. 3rd Semester

    DEFF Research Database (Denmark)

    Exercises in Statistics includes exercises for the tutorials forming a part of the course in statistics at the 3rd semester bachelors programme at the Aarhus School of Business.......Exercises in Statistics includes exercises for the tutorials forming a part of the course in statistics at the 3rd semester bachelors programme at the Aarhus School of Business....

  5. 3rd International Conference on Ecosystem Assessment Management

    CERN Document Server

    Ma, Sheng-Quan; Cao, Hu-hua; Ecosystem Assessment and Fuzzy Systems Management

    2014-01-01

    “Ecosystem Assessment and Fuzzy Systems Management” is the edited outcome of the 3rd International Conference on Ecosystem Assessment Management (ICEAM) and the Workshop on the Construction of an Early Warning Platform for Eco-tourism (WCEWPE) in Hainan on May 5-12, 2013, Haikou, China. The 3rd ICEAM and the WCEWPE, built on the success of previous conferences, are major Symposiums for scientists, engineers and logistic management researchers presenting their the latest achievements, developments and applications in all areas of Ecosystem Assessment Management, Early Warning Platform for Eco-tourism and fuzziology. It aims to strengthen relations between industry research laboratories and universities, and to create a primary symposium for world scientists. The book, containing 47 papers, is divided into five parts: “Ecosystem Assessment, Management and Information”; “Intelligent Algorithm, Fuzzy Optimization and Engineering Application”; “Spatial Data Analysis and Intelligent Information Proces...

  6. Lecture Notes in Statistics. 3rd Semester

    DEFF Research Database (Denmark)

    The lecture note is prepared to meet the requirements for the 3rd semester course in statistics at the Aarhus School of Business. It focuses on multiple regression models, analysis of variance, and log-linear models.......The lecture note is prepared to meet the requirements for the 3rd semester course in statistics at the Aarhus School of Business. It focuses on multiple regression models, analysis of variance, and log-linear models....

  7. 3rd Semester and Master's Thesis Ideas

    DEFF Research Database (Denmark)

    Clausen, Johan

    The following pages contain a list of project ideas proposed by the scientific staff at the department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalouge may form the basis for long and short candidate projects as well as regular 3rd s...

  8. Diagnosis and Fault-tolerant Control, 3rd Edition

    DEFF Research Database (Denmark)

    Blanke, Mogens; Kinnaert, Michel; Lunze, Jan

    The book presents effective model-based analysis and design methods for fault diagnosis and fault-tolerant control. Architectural and structural models are used to analyse the propagation of the fault through the process, to test the fault detectability and to find the redundancies in the process...... that can be used to ensure fault tolerance. It also introduces design methods suitable for diagnostic systems and fault-tolerant controllers for continuous processes that are described by analytical models of discrete-event systems represented by automata....

  9. Entrepreneurship and Small Business : 3rd Asia-Pacific Edition

    OpenAIRE

    Schaper, Michael; Volery, Thierry; Weber, Paull; Lewis, Kate

    2010-01-01

    (See also PDF) PART 1 The nature of small business and entrepreneurship. CHAPTER 1 Entrepreneurship: definition and evolution. CHAPTER 2 The personality of entrepreneurs. CHAPTER 3 Creativity, innovation and entrepreneurship. CHAPTER 4 Small business: definitions and characteristics. PART 2 Getting into business. CHAPTER 5 Options for going into business. CHAPTER 6 Market research and strategy formulation. CHAPTER 7 Preparing a business plan. CHAPTER 7 ...

  10. Resource Guide to Careers in Toxicology, 3rd Edition.

    Science.gov (United States)

    Society of Toxicology, Reston, VA.

    This resource guide was prepared by the Tox 90's Educational Issues Task Force of the Society of Toxicology. The introduction provides information on the Society of Toxicology and financial support for graduate students in toxicology. Other sections include career opportunities in toxicology, academic and postdoctoral programs in toxicology, and…

  11. Legal Concepts in Sport: A Primer. 3rd Edition

    Science.gov (United States)

    Carpenter, Linda Jean

    2008-01-01

    When most people think of legal issues in sport, they think about negligence. However, most professionals will face a much broader range of issues. For instance, topics such as sexual harassment, corporal punishment, drug testing, transportation, and hazing are all of special importance today. Also anti-discrimination laws and the concepts…

  12. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    SUMMARY. Prospective and retrospective investigations were conducted to assess the prevalence and financial losses associated with. Oesophagostomum columbianuminfections of sheep and goats slaughtered at the Maiduguri metropolitan abattoir in the semi- arid zone of Northeastern Nigeria. Out of 184,554 small.

  13. DISTANCE EDUCATION: Definition and Glossary of Terms, 3RD EDITION

    National Research Council Canada - National Science Library

    Reviewed by Ozlem OZAN

    2010-01-01

    Because Distance Education (DE) provides students the new opportunities for accessible and lifelong education, it is getting more and more popular day by day over the entire world, and as stated in the book it has become a major...

  14. Machining Data Handbook. 3rd Edition. Volume 2

    Science.gov (United States)

    1980-01-01

    250 .004 Finishing CA601B CA60GB706 725 754 782 toAn e edo 710 745 757 100RS 715 752 770 • z, ii - 4me 35. COPPER ALLOYS, CAST 3500 100 .001 Roughing...j 10-40j . . . - I i I l l -I Total Form Machining-TFM 10.6 PROCESS SUMMARY same master by adjusting the orbiting cam action. Redress- ing of worn...size- ~ 180 to --20I (# 100 provides a good balance between3600 Orbiting cam cutting rate and reasonable finish.) (adjustable offset) Ram force: Upto

  15. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    Germany at the dose of 50mg/kg IM. Surgical procedure. The middle third of femur above the stifle joint was chosen as the site of operation because it was intact and gives a good cosmetic appearance. The animal was placed in left lateral recumbency and a semicircular lateral and medial incision were made on the surgical ...

  16. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    Although clinical information about T. ptyseos as a human pathogen is limited, this organism has been implicated in tracheotracheo-bronchial/- pulmonary infections such as pneumonitis, asthmatic bronchitis, pharyngitis, Wegener granulomatosis, pneumonia, chronic lung disease, and pulmonary edema (Hollis et al.,. 1981 ...

  17. Thermal radiation heat transfer (3rd revised and enlarged edition)

    Science.gov (United States)

    Siegel, Robert; Howell, John R.

    This book first reviews the overall aspects and background information related to thermal radiation heat transfer and incorporates new general information, advances in analytical and computational techniques, and new reference material. Coverage focuses on radiation from opaque surfaces, radiation interchange between various types of surfaces enclosing a vacuum or transparent medium, and radiation including the effects of partially transmitting media, such as combustion gases, soot, or windows. Boundary conditions and multiple layers are discussed with information on radiation in materials with nonunity refractive indices.

  18. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    treatment and prevention of coccidiosis in poultry and rabbits (McDougald and Reid,. 1997). Sulphaquinoxaline belongs to the sulphonamide group and acts by competing for incorporation of PABA and metabolism of folic acid (McDougald and Reid, 1997). Amprolium and sulphaquinoxaline/diaveridine have been.

  19. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    studies on skeletal muscles have been carried out in different animals by several workers like .... stages of development ±SEM. Table II. Shows the mean weight of muscle in grams (g) of camel at various stages of development ± SEM. .... growth period is caused by hypertrophy and elongation of existing fibres (Iwamato et ...

  20. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    Mastitis may also be associated with viral, bacterial or fungal infections and other toxins (Radostits et al., 2000). Under stressful conditions such as extreme temperatures, muddy and wet living conditions or a sudden change in diet, a doe's immune system is compromised which consequentially suppressed, if not completely ...

  1. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    Rabies prevention in both humans and animals is possible by vaccination. The domestic dog (Canis familiaris) is the major .... as dynamics of dog population in this area is not well studied. Dogs exist in subpopulations, where one .... Wildlife Diseases, 46 :267-271. DZIKWI, A.A., UMOH, J.U, KWAGA, J, K.P., AHMAD, A.A.

  2. Vom work Book Journal, 2011 3rd Edition

    African Journals Online (AJOL)

    USER

    CASE REPORT. On 16th February, 2009, a two year-old. Sudanese ewe weighing about 25 kg was presented to the Ambulatory Unit of the. Veterinary Teaching Hospital, Usmanu. Danfodiyo University, Sokoto. The client's main complaint was presence of wound at perineal region due to accumulation of urine around the.

  3. 3rd International Conference on Robot Intelligence Technology and Applications

    CERN Document Server

    Yang, Weimin; Jo, Jun; Sincak, Peter; Myung, Hyun

    2015-01-01

    This book covers all aspects of robot intelligence from perception at sensor level and reasoning at cognitive level to behavior planning at execution level for each low level segment of the machine. It also presents the technologies for cognitive reasoning, social interaction with humans, behavior generation, ability to cooperate with other robots, ambience awareness, and an artificial genome that can be passed on to other robots. These technologies are to materialize cognitive intelligence, social intelligence, behavioral intelligence, collective intelligence, ambient intelligence and genetic intelligence. The book aims at serving researchers and practitioners with a timely dissemination of the recent progress on robot intelligence technology and its applications, based on a collection of papers presented at the 3rd International Conference on Robot Intelligence Technology and Applications (RiTA), held in Beijing, China, November 6 - 8, 2014. For better readability, this edition has the total 74 papers group...

  4. 3rd MeTrApp Conference

    CERN Document Server

    Lovasz, Erwin-Christian; Hüsing, Mathias

    2015-01-01

    This volume deals with topics such as mechanism and machine design, biomechanics and medical engineering, gears, mechanical transmissions, mechatronics, computational and experimental methods, dynamics of mechanisms and machines, micromechanisms and microactuators, and history of mechanisms and transmissions. Following MeTrApp 2011 and 2013, held under the auspices of the IFToMM, these proceedings of the 3rd Conference on Mechanisms, Transmissions and Applications offer a platform for original research presentations for researchers, scientists, industry experts and students in the fields of mechanisms and transmissions with special emphasis on industrial applications in order to stimulate the exchange of new and innovative ideas.

  5. Classificação da Organização Mundial da Saúde para os tumores dos tecidos hematopoético e linfoide, 4ª edição, 2008: principais modificações introduzidas em relação à 3ª edição, 2001 World Health Organization classification of tumors of hematopoietic and lymphoid tissues, 4th edition, 2008: major changes from the 3rd edition, 2001

    Directory of Open Access Journals (Sweden)

    Maria Claudia Nogueira Zerbini

    2011-02-01

    Full Text Available A Classificação da Organização Mundial da Saúde (OMS para os tumores do tecido hematopoético e linfoide (4ª edição, 2008¹ representa uma atualização da 3ª edição, 2001². Apresentamos a seguir um resumo dessas alterações nos grupos das doenças mieloproliferativas, mileodisplásicas, leucemias mieloides agudas, neoplasias de células precursoras B e T, e neoplasias de células B, T e NK maduras. O entendimento das alterações genético-moleculares e os resultados alcançados com propostas terapêuticas inovadoras nesses grupos de doenças demandam constante reavaliação de sua classificação, justificando as alterações importantes aqui discutidas1,3-5.The World Health Organization (WHO Classification of tumors of hematopoietic and lymphoid tissues (4th edition, 2008¹ presents an updated version of the 3rd edition published in 2001². A summary of these changes relates to the groups of chronic myeloproliferative disorders, myelodisplasia, acute myeloid leukemias, neoplasms of precursor B and T cells and neoplasms derived of mature B, T and NK cells. A better understanding of molecular genetic changes and results achieved with innovative therapeutic approaches in these groups of diseases requires constant reassessment of the classifications, supporting the major changes discussed here, including interesting comments from literature1, 3-5.

  6. 3rd International Conference Nanotechnology and Nanomaterials

    CERN Document Server

    Yatsenko, Leonid

    2016-01-01

    This book presents some of the latest achievements in nanotechnology and nanomaterials from leading researchers in Ukraine, Europe, and beyond. It features contributions from participants in the 3rd International Science and Practice Conference Nanotechnology and Nanomaterials (NANO2015) held in Lviv, Ukraine on August 26-30, 2015. The International Conference was organized jointly by the Institute of Physics of the National Academy of Sciences of Ukraine, University of Tartu (Estonia), Ivan Franko National University of Lviv (Ukraine), University of Turin (Italy), Pierre and Marie Curie University (France), and European Profiles A.E. (Greece). Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key results on topics ranging from nanooptics, nanoplasmonics, and interface studies to energy storage and biomedical applications. Presents cutting-edge advances in nanocomposites and carbon and silicon-based nanomaterials for a wide range of engine...

  7. 3rd CEAS Specialist Conference on Guidance, Navigation and Control

    CERN Document Server

    Drouin, Antoine; Roos, Clément

    2015-01-01

    The two first CEAS (Council of European Aerospace Societies) Specialist Conferences on Guidance, Navigation and Control (CEAS EuroGNC) were held in Munich, Germany in 2011 and in Delft, The Netherlands in 2013. ONERA The French Aerospace Lab, ISAE (Institut Supérieur de l’Aéronautique et de l’Espace) and ENAC (Ecole Nationale de l’Aviation Civile) accepted the challenge of jointly organizing the 3rd edition. The conference aims at promoting new advances in aerospace GNC theory and technologies for enhancing safety, survivability, efficiency, performance, autonomy and intelligence of aerospace systems. It represents a unique forum for communication and information exchange between specialists in the fields of GNC systems design and operation, including air traffic management. This book contains the forty best papers and gives an interesting snapshot of the latest advances over the following topics: l  Control theory, analysis, and design l  Novel navigation, estimation, and tracking methods l  Aircr...

  8. Space Materials Handbook. 3rd; ed.

    Science.gov (United States)

    Rittenhouse, John B.; Singletary, John B.

    1969-01-01

    This edition is the result of an extensive revision and reworking of the second edition of the Space Materials Handbook along with the incorporation of entirely new subject matter coverage and new materials data. All of the most significant material, phenomena, properties, and principles covered in the original Handbook are presented and expanded in this revised and updated version. However, treatment of theoretical aspects has been condensed in order that more emphasis could be placed on the extensive new materials knowledge and data obtained from the design and successful launching of a wide variety of space systems. The handbook is organized into four parts, namely: space environment, effect of space environment on materials, materials in space, and biological interaction with spacecraft materials. Information on mechanical, physical, and chemical properties and characteristics is given for a wide variety of metallic and nonmetallic materials. The effects of natural and induced environments on materials are appraised. Materials categories include coverage of thermal control materials, optical materials, adhesives, organic structural materials, inorganic structural materials, electronic components and materials, materials for sealing applications, and lubrication materials. In addition, a comprehensive multiple citation index is incorporated which gives ready access to information on specific subject areas with regard to their locations within the Handbook.

  9. 3rd Developers@CERN Forum

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    It's about U and I !   The Developers@CERN Forum is an event by developers, for developers, aimed at promoting knowledge and experience sharing. This edition will take place at the IT Amphitheatre, on the 13th, 14th and 15th of February afternoons. It will consist of a series of short presentations and workshops. The topic for this conference will be Frontend & User interfaces. Have you got an idea for a presentation or workshop? Then, tell us about it (deadline on 27th of January). Registration will open in November. Please subscribe to developers-forum-announce@cern.ch mailing list for further information. This event will be made by developers for developers. We are counting on your presence, but also on your contributions! To learn more about the initiative, read the CERN Bulletin article. Organization You can get in touch us at developers-forum-organizers@cern.ch.

  10. Developing Product Lines with 3rd-party components

    NARCIS (Netherlands)

    De Jonge, M.

    2007-01-01

    The trends toward product line development and toward adopting more 3rd-party software are hard to combine. The reason is that productlines demand fine control over the software (e.g., for diversity management), while 3rd-party software (almost by definition) provides only little or no control. A

  11. BOOK REVIEW: Modern Physics, 3rd edn

    Science.gov (United States)

    Lovett, David

    1999-09-01

    The number of broadly based physics texts written at a level corresponding to second year and above of UK physics degrees is limited. This is such a book thoroughly updated in a third edition, the first edition having been published 20 years ago. The book is unusual in that the reader is referred to the Freeman website www.whfreeman.com/physics for some additional sections. It will be interesting to see whether this proves to be an attractive feature. The coverage reflects the US emphasis on topics and contains both theoretical and experimental details. It should not be regarded as an introductory text although it is clearly written. Thus the first two chapters take the reader straight into relativity, concentrating mainly on special relativity but going on to general relativity. From here the reader is led to ideas of quantization of charge, light and energy, followed by an exploration of the nuclear atom, wavelike properties of particles and Schrödinger's equation. Solution of this equation for the hydrogen atom introduces a section on spectroscopy. The next chapter on statistical physics includes Fermi-Dirac and Bose-Einstein statistics and brings to a close Part 1, which concentrates on the theoretical groundwork. Consistent with its title, the book does not cover traditional aspects of thermodynamics and electromagnetic theory. Part 2 is entitled `Applications' and begins with a chapter on molecular structure and spectra. Lasers and masers are included here but geometrical, physical and nonlinear optics get limited or no coverage. Solid state physics follows but, despite the title of the book, there is little on modern devices, although the section on superconductivity mentions high temperature materials. The chapters on nuclear physics, fission, fusion reactors and medical applications and a chapter on particle physics are comprehensive. Finally a chapter on astrophysics and cosmology is referred to, but the reader must find this at the website. As this is

  12. Magnet Free Generators - 3rd Generation Wind Turbine Generators

    DEFF Research Database (Denmark)

    Jensen, Bogi Bech; Mijatovic, Nenad; Henriksen, Matthew Lee

    2013-01-01

    This paper presents an introduction to superconducting wind turbine generators, which are often referred to as 3rd generation wind turbine generators. Advantages and challenges of superconducting generators are presented with particular focus on possible weight and efficiency improvements. A comp....... A comparison of the rare earth usage in different topologies of permanent magnet generators and superconducting generators is also presented....

  13. 3rd Semester and Master’s Thesis Ideas 2013

    DEFF Research Database (Denmark)

    The following pages contain a list of project ideas proposed by the scientific staff at the Department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalogue may form the basis for long and short master projects as well as regular 3rd seme...

  14. 3rd Semester and Master’s Thesis Ideas 2011

    DEFF Research Database (Denmark)

    The report contain a list of project ideas proposed by the scientific staff at the Department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalogue may form the basis for long and short candidate projects as well as regular 3rd semester p...

  15. 3rd Semester and Master’s Thesis Ideas 2012

    DEFF Research Database (Denmark)

    Clausen, Johan

    The report contain a list of project ideas proposed by the scientific staff at the Department of Civil Engineering, Aalborg University, and a number of companies. Most of the project ideas in this catalogue may form the basis for long and short candidate projects as well as regular 3rd semester p...

  16. PREFACE: 3rd International Congress on Mechanical Metrology (CIMMEC2014)

    Science.gov (United States)

    2015-10-01

    From October 14th to 16th 2014, The Brazilian National Institute of Metrology, Quality, and Technology (Inmetro) and the Brazilian Society of Metrology (SBM) organized the 3rd International Congress on Mechanical Metrology (3rd CIMMEC). The 3rd CIMMEC was held in the city of Gramado, Rio Grande do Sul, Brazil. Anticipating the interest and enthusiasm of the technical-scientific community, the Organizing Institutions invite people and organizations to participate in this important congress, reiterating the commitment to organize an event according to highest international standards. This event has been conceived to integrate people and organizations from Brazil and abroad in the discussion of advanced themes in metrology. Manufacturers and dealers of measuring equipment and standards, as well as of auxiliary accessories and bibliographic material, had the chance to promote their products and services in stands at the Fair, which has taken place alongside the Congress. The 3rd CIMMEC consisted of five Keynote Speeches and 116 regular papers. Among the regular papers, the 25 most outstanding ones, comprising a high quality content on Mechanical Metrology, were selected to be published in this issue of Journal of Physics: Conference Series. It is our great pleasure to present this volume of Journal of Physics: Conference Series to the scientific community to promote further research in Mechanical Metrology and related areas. We believe that this volume will be both an excellent source of scientific material in the fast evolving fields that were covered by CIMMEC 2014.

  17. Impressions from the 3rd Nordcode Seminar & Workshop

    DEFF Research Database (Denmark)

    Lenau, Torben Anker; Boelskifte, Per; Hansen, Claus Thorp

    2005-01-01

    This paper summarises the purpose and contents of the 3rd Nordcode Seminar and Workshop. First, the workshop assignments are described. Second, the paper briefly presents the topics of the keynote speeches and all presentations of the working papers that took place in the seminar....

  18. 3rd Session of the Sant Cugat Forum on Astrophysics

    CERN Document Server

    Gravitational wave astrophysics

    2015-01-01

    This book offers review chapters written by invited speakers of the 3rd Session of the Sant Cugat Forum on Astrophysics — Gravitational Waves Astrophysics. All chapters have been peer reviewed. The book goes beyond normal conference proceedings in that it provides a wide panorama of the astrophysics of gravitational waves and serves as a reference work for researchers in the field.

  19. 3rd International Multidisciplinary Microscopy and Microanalysis Congress

    CERN Document Server

    Oral, Zehra

    2017-01-01

    The 3rd International Multidisciplinary Microscopy Congress (InterM2015), held from 19 to 23 October 2015, focused on the latest developments concerning applications of microscopy in the biological, physical and chemical sciences at all dimensional scales, advances in instrumentation, techniques in and educational materials on microscopy. These proceedings gather 17 peer-reviewed technical papers submitted by leading academic and research institutions from nine countries and representing some of the most cutting-edge research available.

  20. 3rd International Conference on Computer & Communication Technologies

    CERN Document Server

    Bhateja, Vikrant; Raju, K; Janakiramaiah, B

    2017-01-01

    The book is a compilation of high-quality scientific papers presented at the 3rd International Conference on Computer & Communication Technologies (IC3T 2016). The individual papers address cutting-edge technologies and applications of soft computing, artificial intelligence and communication. In addition, a variety of further topics are discussed, which include data mining, machine intelligence, fuzzy computing, sensor networks, signal and image processing, human-computer interaction, web intelligence, etc. As such, it offers readers a valuable and unique resource.

  1. 3rd International Conference on Intelligent Technologies and Engineering Systems

    CERN Document Server

    2016-01-01

    This book includes the original, peer reviewed research from the 3rd International Conference on Intelligent Technologies and Engineering Systems (ICITES2014), held in December, 2014 at Cheng Shiu University in Kaohsiung, Taiwan. Topics covered include: Automation and robotics, fiber optics and laser technologies, network and communication systems, micro and nano technologies, and solar and power systems. This book also Explores emerging technologies and their application in a broad range of engineering disciplines Examines fiber optics and laser technologies Covers biomedical, electrical, industrial, and mechanical systems Discusses multimedia systems and applications, computer vision and image & video signal processing.

  2. 3rd International Conference on Movement, Health and Exercise 2016

    CERN Document Server

    Cheong, Jadeera; Usman, Juliana; Ahmad, Mohd; Razman, Rizal; Selvanayagam, Victor

    2017-01-01

    This volume presents the proceedings of the 3rd International Conference on Movement, Health and Exercise 2016 (MoHE2016). The conference was jointly organized by the Biomedical Engineering Department and Sports Centre, University of Malaya. It was held in Malacca, from 28-30 September 2016. MoHE 2016 provided a good opportunity for speakers and participants to actively discuss about recent developments in a wide range of topics in the area of sports and exercise science. In total, 83 presenters and 140 participants took part in this successful conference. .

  3. 3rd Conference on Ignition Systems for Gasoline Engines

    CERN Document Server

    Sens, Marc

    2017-01-01

    The volume includes selected and reviewed papers from the 3rd Conference on Ignition Systems for Gasoline Engines in Berlin in November 2016. Experts from industry and universities discuss in their papers the challenges to ignition systems in providing reliable, precise ignition in the light of a wide spread in mixture quality, high exhaust gas recirculation rates and high cylinder pressures. Classic spark plug ignition as well as alternative ignition systems are assessed, the ignition system being one of the key technologies to further optimizing the gasoline engine.

  4. 3rd Workshop on "Combinations of Intelligent Methods and Applications"

    CERN Document Server

    Palade, Vasile

    2013-01-01

    The combination of different intelligent methods is a very active research area in Artificial Intelligence (AI). The aim is to create integrated or hybrid methods that benefit from each of their components.  The 3rd Workshop on “Combinations of Intelligent Methods and Applications” (CIMA 2012) was intended to become a forum for exchanging experience and ideas among researchers and practitioners who are dealing with combining intelligent methods either based on first principles or in the context of specific applications. CIMA 2012 was held in conjunction with the 22nd European Conference on Artificial Intelligence (ECAI 2012).This volume includes revised versions of the papers presented at CIMA 2012.  .

  5. 3rd International Conference on X-ray Technique

    Science.gov (United States)

    Potrakhov, N. N.; Gryaznov, A. Yu; Lisenkov, A. A.; Kostrin, D. K.

    2017-02-01

    In this preface a brief history, modern aspects and future tendencies in development of the X-ray technique as seen from the 3rd International Conference on X-ray Technique that was held on 24-25 November 2016 in Saint Petersburg, Russia are described On 24-25 November 2016 in Saint Petersburg on the basis of Saint Petersburg State Electrotechnical University “LETI” n. a. V. I. Ulyanov (Lenin) was held the 3rd International Conference on X-ray Technique. The tradition to hold a similar conference in our country was laid in Soviet times. The last of them, the All-Union Conference on the Prospects of X-ray Tubes and Equipment was organized and held more than a quarter century ago - on 21-23 November 1999, at the initiative and under the leadership of the chief engineer of the Leningrad association of electronic industry “Svetlana” Borovsky Alexander Ivanovich and the chief of special design bureau of X-ray devices of “Svetlana” Shchukin Gennady Anatolievich. The most active part in the organization and work of the conference played members of the department of X-ray and electron beam instruments of Leningrad Electrotechnical Institute “LETI” (the former name of Saint Petersburg State Electrotechnical University “LETI”), represented by head of the department professor Ivanov Stanislav Alekseevich.

  6. Strategies of Qualitative Inquiry. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna S., Ed.

    2007-01-01

    "Strategies of Qualitative Inquiry, Third Edition," the second volume in the paperback version of "The SAGE Handbook of Qualitative Research, 3rd Edition," consists of Part III of the handbook ("Strategies of Inquiry"). "Strategies of Qualitative Inquiry, Third Edition" presents the major tactics--historically, the research methods--that…

  7. Distance of mandibular foramen from 3 rd molar tooth in dry adult ...

    African Journals Online (AJOL)

    The aim of this study was to determine the distance of MF from 3rd molar tooth in both genders. Seventy dry adult mandible were included in this study. Mandible having 3rd molar tooth was selected for the study. Distance of MF from mid point of 3rd molar tooth to anterior margin of MF was measured with Vernier caliper.

  8. 3rd International Conference on Computational Mathematics and Computational Geometry

    CERN Document Server

    Ravindran, Anton

    2016-01-01

    This volume presents original research contributed to the 3rd Annual International Conference on Computational Mathematics and Computational Geometry (CMCGS 2014), organized and administered by Global Science and Technology Forum (GSTF). Computational Mathematics and Computational Geometry are closely related subjects, but are often studied by separate communities and published in different venues. This volume is unique in its combination of these topics. After the conference, which took place in Singapore, selected contributions chosen for this volume and peer-reviewed. The section on Computational Mathematics contains papers that are concerned with developing new and efficient numerical algorithms for mathematical sciences or scientific computing. They also cover analysis of such algorithms to assess accuracy and reliability. The parts of this project that are related to Computational Geometry aim to develop effective and efficient algorithms for geometrical applications such as representation and computati...

  9. 3rd grade English language learners making sense of sound

    Science.gov (United States)

    Suarez, Enrique; Otero, Valerie

    2013-01-01

    Despite the extensive body of research that supports scientific inquiry and argumentation as cornerstones of physics learning, these strategies continue to be virtually absent in most classrooms, especially those that involve students who are learning English as a second language. This study presents results from an investigation of 3rd grade students' discourse about how length and tension affect the sound produced by a string. These students came from a variety of language backgrounds, and all were learning English as a second language. Our results demonstrate varying levels, and uses, of experiential, imaginative, and mechanistic reasoning strategies. Using specific examples from students' discourse, we will demonstrate some of the productive aspects of working within multiple language frameworks for making sense of physics. Conjectures will be made about how to utilize physics as a context for English Language Learners to further conceptual understanding, while developing their competence in the English language.

  10. 3rd International Conference on Nanotechnologies and Biomedical Engineering

    CERN Document Server

    Tiginyanu, Ion

    2016-01-01

    This volume presents the proceedings of the 3rd International Conference on Nanotechnologies and Biomedical Engineering which was held on September 23-26, 2015 in Chisinau, Republic of Moldova. ICNBME-2015 continues the series of International Conferences in the field of nanotechnologies and biomedical engineering. It aims at bringing together scientists and engineers dealing with fundamental and applied research for reporting on the latest theoretical developments and applications involved in the fields. Topics include Nanotechnologies and nanomaterials Plasmonics and metamaterials Bio-micro/nano technologies Biomaterials Biosensors and sensors systems Biomedical instrumentation Biomedical signal processing Biomedical imaging and image processing Molecular, cellular and tissue engineering Clinical engineering, health technology management and assessment; Health informatics, e-health and telemedicine Biomedical engineering education Nuclear and radiation safety and security Innovations and technology transfer...

  11. 3rd Symposium on Space Optical Instruments and Applications

    CERN Document Server

    Zhang, Guangjun

    2017-01-01

    This volume contains selected and expanded contributions presented at the 3rd Symposium on Space Optical Instruments and Applications in Beijing, China June 28 – 29, 2016. This conference series is organised by the Sino-Holland Space Optical Instruments Laboratory, a cooperation platform between China and the Netherlands. The symposium focused on key technological problems of optical instruments and their applications in a space context. It covered the latest developments, experiments and results regarding theory, instrumentation and applications in space optics. The book is split across five topical sections. The first section covers space optical remote sensing system design, the second advanced optical system design, the third remote sensor calibration and measurement. Remote sensing data processing and information extraction is then presented, followed by a final section on remote sensing data applications. .

  12. 3rd Workshop on Branching Processes and their Applications

    CERN Document Server

    González, Miguel; Gutiérrez, Cristina; Martínez, Rodrigo; Minuesa, Carmen; Molina, Manuel; Mota, Manuel; Ramos, Alfonso; WBPA15

    2016-01-01

    This volume gathers papers originally presented at the 3rd Workshop on Branching Processes and their Applications (WBPA15), which was held from 7 to 10 April 2015 in Badajoz, Spain (http://branching.unex.es/wbpa15/index.htm). The papers address a broad range of theoretical and practical aspects of branching process theory. Further, they amply demonstrate that the theoretical research in this area remains vital and topical, as well as the relevance of branching concepts in the development of theoretical approaches to solving new problems in applied fields such as Epidemiology, Biology, Genetics, and, of course, Population Dynamics. The topics covered can broadly be classified into the following areas: 1. Coalescent Branching Processes 2. Branching Random Walks 3. Population Growth Models in Varying and Random Environments 4. Size/Density/Resource-Dependent Branching Models 5. Age-Dependent Branching Models 6. Special Branching Models 7. Applications in Epidemiology 8. Applications in Biology and Genetics Offer...

  13. 3rd International Symposium for Intelligent Transportation and Smart City

    CERN Document Server

    Xie, Xiongyao; Sun, Jian; Ma, Limin; Chen, Yinong; ITASC

    2017-01-01

    This book presents research advances in intelligent transportation and smart cities in detail, mainly focusing on green traffic and urban utility tunnels, presented at the 3rd International Symposium for Intelligent Transportation and Smart City (ITASC) held at Tongji University, Shanghai, on May 19–20, 2017. It discusses a number of hot topics, such as the 2BMW system (Bus, Bike, Metro and Walking), transportation safety and environmental protection, urban utility design and application, as well as the application of BIM (Building Information Modeling) in city design. By connecting the theory and applications of intelligent transportation in smart cities, it enhances traffic efficiency and quality. The book gathers numerous selected papers and lectures, including contributions from respected scholars and the latest engineering advances, to provide guidance to researchers in the field of transportation and urban planning at universities and in related industries. The first conference in the ITASC series sta...

  14. 3rd Computer Science On-line Conference

    CERN Document Server

    Senkerik, Roman; Oplatkova, Zuzana; Silhavy, Petr; Prokopova, Zdenka

    2014-01-01

    This book is based on the research papers presented in the 3rd Computer Science On-line Conference 2014 (CSOC 2014).   The conference is intended to provide an international forum for discussions on the latest high-quality research results in all areas related to Computer Science. The topics addressed are the theoretical aspects and applications of Artificial Intelligences, Computer Science, Informatics and Software Engineering.   The authors provide new approaches and methods to real-world problems, and in particular, exploratory research that describes novel approaches in their field. Particular emphasis is laid on modern trends in selected fields of interest. New algorithms or methods in a variety of fields are also presented.   This book is divided into three sections and covers topics including Artificial Intelligence, Computer Science and Software Engineering. Each section consists of new theoretical contributions and applications which can be used for the further development of knowledge of everybod...

  15. 3rd International Workshop on Turbulent Spray Combustion

    CERN Document Server

    Gutheil, Eva

    2014-01-01

    This book reflects the results of the 2nd and 3rd International Workshops on Turbulent Spray Combustion. The focus is on progress in experiments and numerical simulations for two-phase flows, with emphasis on spray combustion. Knowledge of the dominant phenomena and their interactions allows development of predictive models and their use in combustor and gas turbine design. Experts and young researchers present the state-of-the-art results, report on the latest developments and exchange ideas in the areas of experiments, modelling and simulation of reactive multiphase flows. The first chapter reflects on flame structure, auto-ignition and atomization with reference to well-characterized burners, to be implemented by modellers with relative ease. The second chapter presents an overview of first simulation results on target test cases, developed at the occasion of the 1st International Workshop on Turbulent Spray Combustion. In the third chapter, evaporation rate modelling aspects are covered, while the fourth ...

  16. Organizational Knowledge Communication – a Nascent 3rd Order Disciplinarity

    DEFF Research Database (Denmark)

    Kastberg, Peter

    2014-01-01

    to Organizational Knowledge Communication, i.e., organization studies, communication theory and Knowledge Management, respectively. In their synthesis the three trajectories form a disciplinary triple helix, a triple helix which, in turn, gives rise to Organizational Knowledge Communication as a novel, 3rd order......There is an emerging tendency that the organizational communication functions of larger companies enter into a symbiotic relationship with the companies’ Knowledge Management function. A tendency this journal has labelled Organizational Knowledge Communication. This should come as no surprise...... to neither the researcher nor the practitioner; after all who can say where a corporation’s knowledge work ends and where its organizational communication begins – and vice versa? In this paper I will present a theoretical account of the three disciplinary trajectories that, in my view, have given rise...

  17. PREFACE: 3rd International Conference of Mechanical Engineering Research (ICMER 2015)

    Science.gov (United States)

    Mamat, Riazalman; Rahman, Mustafizur; Mohd. Zuki Nik Mohamed, Nik; Che Ghani, Saiful Anwar; Harun, Wan Sharuzi Wan

    2015-12-01

    The 3rd ICMER2015 is the continuity of the NCMER2010. The year 2010 represents a significant milestone in the history for Faculty of Mechanical Engineering, Universiti Malaysia Pahang (UMP) Malaysia with the organization of the first and second national level conferences (1st and 2nd NCMER) at UMP on May 26-27 and Dec 3-4 2010. The Faculty then changed the name from National Conference on Mechanical Engineering Research (NCMER) to International Conference on Mechanical Engineering Research (ICMER) in 2011 and this year, 2015 is our 3rd ICMER. These proceedings contain the selected scientific manuscripts submitted to the conference. It is with great pleasure to welcome you to the "International Conference on Mechanical Engineering Research (ICMER2015)" that is held at Zenith Hotel, Kuantan, Malaysia. The call for papers attracted submissions of over two hundred abstracts from twelve different countries including Japan, Iran, China, Kuwait, Indonesia, Norway, Philippines, Morocco, Germany, UAE and more. The scientific papers published in these proceedings have been revised and approved by the technical committee of the 3rd ICMER2015. All of the papers exhibit clear, concise, and precise expositions that appeal to a broad international readership interested in mechanical engineering, combustion, metallurgy, materials science as well as in manufacturing and biomechanics. The reports present original ideas or results of general significance supported by clear reasoning and compelling evidence, and employ methods, theories and practices relevant to the research. The authors clearly state the questions and the significance of their research to theory and practice, describe how the research contributes to new knowledge, and provide tables and figures that meaningfully add to the narrative. In this edition of ICMER representatives attending are from academia, industry, governmental and private sectors. The plenary and invited speakers will present, discuss, promote and

  18. 3rd Course of the International School of Advanced Geodesy

    CERN Document Server

    Sansò, Fernando

    1985-01-01

    During the period April 25th to May 10th, 1984 the 3rd Course of the International School of Advanced Geodesy entitled "Optimization and Design of Geodetic Networks" took place in Erice. The main subject of the course is clear from the title and consisted mainly of that particular branch of network analysis, which results from applying general concepts of mathematical optimization to the design of geodetic networks. As al­ ways when dealing with optimization problems, there is an a-priori choice of the risk (or gain) function which should be minimized (or maximized) according to the specific interest of the "designer", which might be either of a scientific or of an economic nature or even of both. These aspects have been reviewed in an intro­ ductory lecture in which the particular needs arising in a geodetic context and their analytical representations are examined. Subsequently the main body of the optimization problem, which has been conven­ tionally divided into zero, first, second and third order desi...

  19. The 3rd irradiation test plan of DUPIC fuel

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Myung Seung; Song, K. C.; Park, J. H. and others

    2001-05-01

    The objective of the 3rd irradiation test of DUPIC fuel at the HANARO is to estimate the in-core behaviour of a DUPIC pellet that is irradiated up to more than average burnup of CANDU fuel. The irradiation of DUPIC fuel is planned to start at May 21, 2001, and will be continued at least for 8 months. The burnup of DUPIC fuel through this irradiation test is thought to be more than 7,000 MWd/tHE. The DUPIC irradiation rig instrumented with three SPN detectors will be used to accumulate the experience for the instrumented irradiation and to estimate the burnup of irradiated DUPIC fuel more accurately. Under normal operating condition, the maximum linear power of DUPIC fuel was estimated as 55.06 kW/m, and the centerline temperature of a pellet was calculated as 2510 deg C. In order to assess the integrity of DUPIC fuel under the accident condition postulated at the HANARO, safety analyses on the locked rotor and reactivity insertion accidents were carried out. The maximum centerline temperature of DUPIC fuel was estimated 2590 deg C and 2094 deg C for each accident, respectively. From the results of the safety analysis, the integrity of DUPIC fuel during the HANARO irradiation test will be secured. The irradiated DUPIC fuel will be transported to the IMEF. The post-irradiation examinations are planned to be performed at the PIEF and IMEF.

  20. Academic Training: 3rd Term - 01 April - 30 June 2005

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2004 - 2005 ACADEMIC TRAINING PROGRAMME 3rd Term - 01 April - 30 June 2005 REGULAR LECTURE PROGRAMME Monte Carlo generators fot the LHC by T. Sjostrand / CERN-PH 4, 5, 6, 7 April The LHC machine experiment interface by S. Tapprogge / Univ. Gutenberg, Mainz, D R. Assmann, CERN-AB, E. Tsesmelis and D. Macina / CERN-TS 18, 19, 20, 21, 22 April Cosmology for particle physicists by S. Carroll / Univ. of Chicago, USA 9, 10, 11, 12, 13 May The ITER projects: technological challenges by P. Bruzzone / EPFL CRPP, Zürich, CH J. Lister / EPFL CRPP, Lausanne, CH 30, 31 May, 1, 2, 3 June String theory by C. Johnson / Univ. of Southern California, USA 6, 7, 8, 9, 10 June Small may be beautiful By M. Davier / LAL, Orsay, F. T. Soldner / ILL, Grenoble, F. 13, 14, 15, 16, 17 June Climate change and challenges for the environment by C. Schluchter / Univ. Bern. CH 20, 21, 22 June LECTURE SERIES FOR POSTGRADUATE STUDENTS Particle detectors - principles and techniques by C. Joram, L. Ropelewski, M. Moll, C. ...

  1. The 3rd colloquium on process simulation. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Jokilaakso, A. [ed.

    1996-12-31

    The presentations collected in this volume were presented at the 3rd Colloquium on Process Simulation held at Helsinki University of Technology, Espoo, Finland, June 12-14, 1996. In the more developed industrial nations, the processes for producing chemicals, energy, and materials encounter environmental concern and laws which challenge engineers to develop the processes towards more efficient, economical and safe operation. This necessitates more thorough understanding of the processes and phenomena involved. Formerly, the development of the processes was largely based on trial and error, whereas today, the development of computer performance together with the diversification of modelling software enables simulation of the processes. The increased capacity and possibilities for modelling the processes brought by the improved hardware and software, have generated a strong demand for more accurate mathematical descriptions of the processes. Especially, the coupling of computational fluid dynamics and chemical kinetics, combustion, and thermodynamics is of current interest in process oriented technology. This colloquium attempts to give examples of modelling efforts in operation in different universities, research institutes and companies. Furthermore, the aim of this colloquium is to offer an annual opportunity to the researchers to come together and discuss their common problems and the state of their investigations

  2. EEI environmental directory of U. S. power plants, 3rd Edition

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    Air pollution control equipment for particulate, NO[sub x] and SO[sub x] emissions, solid waste disposal methods and cooling water systems are the focus of this new directory. Precipitators, scrubbers, boiler vendors and firing configuration are identified for approximately 2,500 steam-electric units at 950 power generation sites. Basic power plant design data includes unit age, capacity, and fuel type.

  3. Best Practice in Motivation and Management in the Classroom. 3rd Edition

    Science.gov (United States)

    Wiseman, Denise G.; Hunt, Gilbert H.

    2013-01-01

    Having the ability to manage the learning environment, motivate students in the environment, and offer instruction that itself is motivating and which contributes to students learning what they need to learn and acquiring skills they need to acquire characterizes effective teachers. To meet these expectations, teachers need highly developed skills…

  4. Planning Schools for Use of Audio-Visual Materials. No. 1--Classrooms, 3rd Edition.

    Science.gov (United States)

    National Education Association, Washington, DC.

    Intended to inform school board administrators and teachers of the current (1958) thinking on audio-visual instruction for use in planning new buildings, purchasing equipment, and planning instruction. Attention is given the problem of overcoming obstacles to the incorporation of audio-visual materials into the curriculum. Discussion includes--(1)…

  5. Honors Programs at Smaller Colleges. 3rd Edition. National Collegiate Honors Council Monograph Series

    Science.gov (United States)

    Schuman, Samuel

    2011-01-01

    This monograph focuses upon areas of special concern to those working with honors at smaller colleges and universities: mission, recruitment, facilities, administration, budget, and curriculum. In each area, the author makes some general suggestions about overall operating principles, note specific issues that can lead to difficulties, and suggest…

  6. Joint Logistic Commanders’ Guide for the Management of Joint Service Programs. 3rd Edition

    Science.gov (United States)

    1987-01-01

    be established * Program Office Organization and and accomplished in accordance with Initial Staffing, including in the case of DoDD 5000.1 of 12...alternatives for pro- A complicating factor ip the organiza- gram office organization . One is to in- tion of a jointly staffed progr’.m office elude all...99-433, 1 a Each joint program manager must October 1986. Title IV - Joint Officer Personnel tailor the program office organization to Policy

  7. Gavel to Gavel: A Guide to the Televised Proceedings of Congress. 3rd Edition.

    Science.gov (United States)

    Green, Alan

    C-SPAN is a non-profit public service television network created by the U.S. cable television industry to provide viewers live gavel-to-gavel access to the proceedings of the U.S. House of Representatives and the U.S. Senate, and to other forums where public policy is discussed, debated, and decided. This guide presents a brief history of how…

  8. Methodology Guidelines on Life Cycle Assessment of Photovoltaic Electricity: 3rd Edition

    Energy Technology Data Exchange (ETDEWEB)

    Frischknecht, Rolf; Heath, Garvin; Raugei, Marco; Sinha, Parikhit; de Wild-Scholten, Mariska

    2016-01-01

    Life Cycle Assessment (LCA) is a structured, comprehensive method of quantifying material- and energy-flows and their associated emissions caused in the life cycle of goods and services. The ISO 14040 and 14044 standards provide the framework for LCA. However, this framework leaves the individual practitioner with a range of choices that can affect the results and thus the conclusions of an LCA study. The current IEA guidelines were developed to provide guidance on assuring consistency, balance, and quality to enhance the credibility and reliability of the results from LCAs on photovoltaic (PV) electricity generation systems. The guidelines represent a consensus among the authors - PV LCA experts in North America, Europe, and Asia - for assumptions made on PV performance, decisions on process input and emissions allocation, methods of analysis, and reporting of the results. Guidance is given on PV-specific parameters used as inputs in LCA and on choices and assumptions in life cycle inventory (LCI) data analysis and on implementation of modeling approaches. A consistent approach towards system modeling, the functional unit, the system boundaries, water use modeling and the allocation aspects enhances the credibility of PV electricity LCA studies and enables balanced LCA-based comparisons of different electricity producing technologies. The document discusses metrics like greenhouse gas emissions (GHG), cumulative energy demand (CED), acidification potential (AP), ozone depletion potential (ODP), human toxicity, ecotoxicity and ionizing radiation. Guidance is given for the definition of the energy payback time (EPBT), the nonrenewable energy payback time (NREPBT), and the impact mitigation potentials (IMP). The indicator energy return on investment (EROI) is described in a separate International Energy Agency (IEA) PV Power Systems (PVPS) Task 12 report (Raugei et al. 2015). The guidelines on the reporting and communication of the results serve the need for producing clear, comprehensive and transparent reports.

  9. Introduction to Recreation Services for People with Disabilities: A Person-Centered Approach. 3rd Edition

    Science.gov (United States)

    Bullock, Charles C.; Mahon, Michael J.; Killingsworth, Charles L.

    2010-01-01

    Ultimately, all successful recreation programs center around its participants wants and needs. Serving people with disabilities is no exception. "Introduction to Recreation Services for People with Disabilities" is intended to be an introductory book for anyone planning or working in the parks, recreation, and leisure service industry. Through…

  10. An introduction to Kolmogorov complexity and its applications. - 3rd edition

    NARCIS (Netherlands)

    Li, M.; Vitányi, P.

    2008-01-01

    Written by two experts in the field, this book is ideal for advanced undergraduate students, graduate students, and researchers in all fields of science. It is self-contained: it contains the basic requirements from mathematics, probability theory, statistics, information theory, and computer

  11. Frisbee - the first artificial cervical disc of 3RD generation

    Directory of Open Access Journals (Sweden)

    Karin Büttner-Janz

    2014-03-01

    Full Text Available OBJECTIVE: The current cervical disc arthroplasty is limited by postoperative facet joint arthritis, heterotopic ossification and segmental kyphosis. The total Frisbee disc, which has an upper convex/concave non-spherical surface and a lower flat sliding surface, is a new approach for improved outcomes. Prior to clinical application, safety and suitability tests are required. METHODS: The Frisbee is the first 3rd generation disc according to a new classification of total disc because it can precisely mimic the segmental ROM, including the soft limitation of axial rotation. The ISO 18192-1 test was carried out to determine the rate of wear debris. A FE model was used to assess the safety of prosthetic components. In the sagittal plane several variables to determine the most favorable lordotic angle were evaluated. RESULTS: Two angled prosthetic plates are safer than one sliding angled core to prevent the displacement. The lordosis of 7° of the Frisbee leads to kyphosis of no more than 2° without reduction of the ROM. The wear rate of the Frisbee is five times smaller compared to an FDA-approved disc with a spherical sliding surface. CONCLUSIONS: Based on the test results, the clinical application of Frisbee can now be studied. The postoperative kyphosis observed with other devices is not an issue with the Frisbee design. Physiological ROM is combined with the significant reduction of wear debris. For these reasons the Frisbee has the potential to provide a better balanced segmental loading reducing the degeneration of the joint surface and heterotopic ossification.

  12. The radiology of joint disease. 3rd Ed

    Energy Technology Data Exchange (ETDEWEB)

    Forrester, D.M.; Brown, J.C.

    1987-01-01

    The book is a systematic radiographic approach to the arthritides. Part one deals with hand abnormalities ''to facilitate the teaching of basic principles and to dramatize the differences between radiographic features of various arthritides,'' as stated in the forward of the first edition. Part two, ''Arthritis from Head to Foot,'' illustrates the same diseases as they affect other joints. The ABCs (alignment, bone mineralization, cartilage space, soft tissue) approach is followed throughout the book. For example, reflex sympathetic dystrophy syndrome is dealt with in six different locations, and metatarsal stress fractures are mentioned in a chapter on erosions in rheumatoid arthritis.

  13. PREFACE: 3rd International Symposium ''Optics and its Applications''

    Science.gov (United States)

    Calvo, M. L.; Dolganova, I. N.; Gevorgyan, N.; Guzman, A.; Papoyan, A.; Sarkisyan, H.; Yurchenko, S.

    2016-01-01

    The SPIE.FOCUS Armenia: 3rd International Symposium ''Optics and its Applications'' (OPTICS-2015) http://rau.am/optics2015/ was held in Yerevan, Armenia, in the period October 1 - 5, 2015. The symposium was organized by the International Society for Optics and Photonics (SPIE), the Armenian SPIE student chapter with collaboration of the Armenian TC of ICO, the Russian-Armenian University (RAU), the Institute for Physical Research of National Academy of Sciences of Armenia (IPR of NAS), the Greek-Armenian industrial company LT-PYRKAL, and the Yerevan State University (YSU). The Symposium was co-organized by the SPIE & OSA student chapters of BMSTU, the Armenian OSA student chapter, and the SPIE student chapters of Lund University and Wroclaw University of Technology. The symposium OPTICS-2015 was dedicated to the International Year of Light and Light-Based Technologies. OPTICS-2015 was devoted to modern topics and optical technologies such as: optical properties of nanostructures, silicon photonics, quantum optics, singular optics & its applications, laser spectroscopy, strong field optics, biomedical optics, nonlinear & ultrafast optics, photonics & fiber optics, and mathematical methods in optics. OPTICS-2015 was attended by 100 scientists and students representing 17 countries: Armenia, China, Czech Republic, France, Georgia, Germany, India, Iran, Italy, Latvia, Mexico, Poland, Russia, Saudi Arabia, Sweden, Ukraine, and USA. Such a broad international community confirmed the important mission of science to be a uniting force between different countries, religions, and nations. We hope that OPTICS-2015 inspired and motivated students and young scientists to work in optics and in science in general. The present volume of Journal of Physics: Conference Series includes proceedings of the symposium covering various aspects of modern problems in optics. We are grateful to all people who were involved in the organization process. We gratefully acknowledge support from

  14. 3rd Active Flow and Combustion Control Conference

    CERN Document Server

    2015-01-01

    The book reports on the latest theoretical and experimental advances in the  field of active flow and combustion control. It covers new developments in actuator technology and sensing, in robust and optimal open- and closed-loop control, as well as in model reduction for control. It collects contributions presented during the third edition of the Active Flow and Combustion Control conference, held in September 10-12, 2014 at the Technische Universität Berlin (Germany). This conference, as well as the research presented in the book, have been supported by the collaborative research center SFB 1029 -Substantial efficiency increase in gas turbines through direct use of coupled unsteady combustion and flow dynamics, funded by the DFG (German Research Foundation).

  15. PREFACE: 3rd International Congress on Ceramics (ICC3)

    Science.gov (United States)

    Niihara, Koichi; Ohji, Tatsuki; Sakka, Yoshio

    2011-10-01

    Early in 2005, the American Ceramic Society, the European Ceramic Society and the Ceramic Society of Japan announced a collaborative effort to provide leadership for the global ceramics community that would facilitate the use of ceramic and glass materials. That effort resulted in an agreement to organize a new biennial series of the International Congress on Ceramics, convened by the International Ceramic Federation (ICF). In order to share ideas and visions of the future for ceramic and glass materials, the 1st International Congress on Ceramics (ICC1) was held in Canada, 2006, under the organization of the American Ceramic Society, and the 2nd Congress (ICC2) was held in Italy, 2008, hosted by the European Ceramic Society. Organized by the Ceramic Society of Japan, the 3rd Congress (ICC3) was held in Osaka, Japan, 14-18 November 2010. Incorporating the 23rd Fall Meeting of the Ceramic Society of Japan and the 20th Iketani Conference, ICC3 was also co-organized by the Iketani Science and Technology Foundation, and was endorsed and supported by ICF, Asia-Oceania Ceramic Federation (AOCF) as well as many other organizations. Following the style of the previous two successful Congresses, the program was designed to advance ceramic and glass technologies to the next generation through discussion of the most recent advances and future perspectives, and to engage the worldwide ceramics community in a collective effort to expand the use of these materials in both conventional as well as new and exciting applications. ICC3 consisted of 22 voluntarily organized symposia in the most topical and essential themes of ceramic and glass materials, including Characterization, design and processing technologies Electro, magnetic and optical ceramics and devices Energy and environment related ceramics and systems Bio-ceramics and bio-technologies Ceramics for advanced industry and safety society Innovation in traditional ceramics It also contained the Plenary Session and the

  16. Chondromyxoid fibroma of distal 1/3 rd of fibula a rare tumour at rare ...

    African Journals Online (AJOL)

    Chondromyxoid fibromas are rare, benign tumours account for <1% of primary bone neoplasms. Most commonly affected in 2nd and 3rdof life. We report one such case of chondromyxoid fibroma in distal fibula of a 15-year-old girl. The patient was managed with lower 3rd fibulectomy and fibular turnoplasty from middle 3rd ...

  17. Exercises in statistics for HA & HA(dat.) & BSc(B), 3rd semester

    DEFF Research Database (Denmark)

    The booklet contains excercises to be used for the tutorials related to the 3rd semester course in statistics on the bachelors progarmme at the Aarhus School of Business.......The booklet contains excercises to be used for the tutorials related to the 3rd semester course in statistics on the bachelors progarmme at the Aarhus School of Business....

  18. GPM Ground Validation Airborne Precipitation Radar 3rd Generation (APR-3) OLYMPEX V2.3

    Data.gov (United States)

    National Aeronautics and Space Administration — The GPM Ground Validation Airborne Precipitation Radar 3rd Generation (APR-3) OLYMPEX dataset was collected from November 12, 2015 to December 19, 2015 during the...

  19. Radiographic findings on 3rd molars removed in 20-year-old men.

    Science.gov (United States)

    Rajasuo, Ari; Peltola, Jaakko; Ventä, Irja; Murtomaa, Heikki

    2003-10-01

    In this study we assess radiographic findings characteristic of mandibular 3rd molars that had required either routine or surgical extraction. X-ray findings relating to acute pericoronitis were also examined. The material was collected by investigating patient records and rotational panoramic radiographs of 20-year-old Finnish male conscripts (n = 738) treated during military service because of 3rd-molar-related problems. The follicle around the crown of mandibular 3rd molars with acute pericoronitis was enlarged in 19% of cases and in 13% of chronic symptom-free pericoronitis cases (not statistically significant difference). Mandibular 3rd molars extracted surgically were more often mesially inclined than those extracted routinely (61% vs. 23%; P pericoronitis [around 27% vs. 39% of the teeth routinely extracted (OR 0.5, 95% CI 0.3-0.8)]. In 86% of cases the space between 2nd molar and ramus of the mandible was narrower than the 3rd molar extracted surgically, whereas this was 62% in routine extraction cases (P < 0.001). We conclude that there are some typical 3rd-molar findings in rotational panoramic radiographs that show a need for surgical extraction.

  20. File list: InP.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Lar.05.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX016173,SRX288024...87921,SRX287718,SRX331401,SRX287658,SRX331366,SRX287906,SRX287678 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.05.AllAg.3rd_instar.bed ...

  1. File list: Pol.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Lar.50.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.50.AllAg.3rd_instar.bed ...

  2. File list: Unc.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Lar.50.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX022335,SRX032124,SRX032123,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.50.AllAg.3rd_instar.bed ...

  3. File list: Oth.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Lar.50.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX318781,SRX31878...5306 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.50.AllAg.3rd_instar.bed ...

  4. File list: ALL.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Lar.20.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX1038029,SRX103803...SRX013082,SRX467107,SRX016173,SRX215499,SRX495243,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.3rd_instar.bed ...

  5. File list: ALL.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Lar.05.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX104964,SRX104963,...SRX287718,SRX331401,SRX287658,SRX331366,SRX287906,SRX287678 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.3rd_instar.bed ...

  6. File list: Unc.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Lar.05.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038031,SRX103802...9,SRX1038032,SRX1038030,SRX022335,SRX022334,SRX032124,SRX013058,SRX032123 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.05.AllAg.3rd_instar.bed ...

  7. File list: Unc.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Lar.10.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX032124,SRX032123,SRX022335,SRX022334,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.10.AllAg.3rd_instar.bed ...

  8. File list: Pol.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Lar.05.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287907,SRX28790...8,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.05.AllAg.3rd_instar.bed ...

  9. File list: Unc.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Lar.20.AllAg.3rd_instar dm3 Unclassified Larvae 3rd instar SRX1038029,SRX103803...1,SRX1038032,SRX1038030,SRX022335,SRX032124,SRX022334,SRX032123,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Lar.20.AllAg.3rd_instar.bed ...

  10. File list: InP.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Lar.50.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX287726,SRX331369...87917,SRX287921,SRX288023,SRX467107,SRX016172,SRX016173 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.50.AllAg.3rd_instar.bed ...

  11. File list: InP.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Lar.20.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX467108,SRX287726...67103,SRX288024,SRX288023,SRX104976,SRX016172,SRX467107,SRX016173 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.20.AllAg.3rd_instar.bed ...

  12. File list: Pol.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Lar.20.AllAg.3rd_instar dm3 RNA polymerase Larvae 3rd instar SRX287908,SRX28790...7,SRX013070,SRX013082 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Lar.20.AllAg.3rd_instar.bed ...

  13. File list: InP.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Lar.10.AllAg.3rd_instar dm3 Input control Larvae 3rd instar SRX016172,SRX016173...87701,SRX287922,SRX467104,SRX287918,SRX287718,SRX104976,SRX467107 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Lar.10.AllAg.3rd_instar.bed ...

  14. File list: ALL.Lar.50.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Lar.50.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX1038029,SRX103803...SRX467060,SRX495306,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.3rd_instar.bed ...

  15. File list: Oth.Lar.05.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Lar.05.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX104964,SRX10496...1403,SRX495243 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.05.AllAg.3rd_instar.bed ...

  16. File list: ALL.Lar.10.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Lar.10.AllAg.3rd_instar dm3 All antigens Larvae 3rd instar SRX104963,SRX104968,...SRX287718,SRX022334,SRX104976,SRX467107,SRX013086,SRX013058 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.10.AllAg.3rd_instar.bed ...

  17. File list: Oth.Lar.20.AllAg.3rd_instar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Lar.20.AllAg.3rd_instar dm3 TFs and others Larvae 3rd instar SRX318781,SRX31878...1403,SRX495243 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Lar.20.AllAg.3rd_instar.bed ...

  18. The Role of Training and Promotion to Increase The 3rd Party Funds Indonesian Islamic Banking

    Directory of Open Access Journals (Sweden)

    Rahmat Hidayat

    2014-03-01

    Full Text Available Objective – This study aims to determine whether the role of training is much larger than the promotion in raising third-party funds in Islamic banks in Indonesia given the cost of the training is spent is greater than the cost of promotion. This study empirically examines the relationship and impact of training and promotion to raise funds for a 3rd party in Indonesia Islamic banks.Methods – This study uses secondary data Islamic commercial banks in the form of panel (time-series and cross-section of Bank Indonesia data from 2010 until 2012. There are two independent variables training cost (X1 and promotion cost (X2 and one dependent variable is 3rd-party funds (Y. The analysis technique used path analysis to examine the role of training and the promotion of financial performance (The 3rd Party Funds.Result – Simultaneously, training and promotion gives an effect by 52%, and partially or individual training gives an insignificant negative effect, while the promotion has a significant positive impact on financial performance (financial-party funds on Islamic banking.Conclusion – The role of promotion is higher in raising The 3rd Party Funds than training. Keywords : Cost, Training, Promotion, The 3rd Party Funds 

  19. Impact of 3rd-order dispersion on photonic time-stretch system

    Science.gov (United States)

    Liu, Changqiao; Jin, Xiaofeng; Xu, Boyu; Jin, Xiangdong; Zhang, Xianmin; Zheng, Shilie; Chi, Hao

    2017-11-01

    In this paper, we present a particular theoretical analysis of the impact of 3rd-order dispersion on the photonic time-stretch (PTS) system. Analytical expressions of all harmonics with time-dependent attenuation caused by 3rd-order dispersion of the PTS system are derived, for the first time to the best of our knowledge. The theoretical analysis is based on strict derivation rather than small signal modulation. The effectiveness of the analytical model is verified by a simulated experiment. Our proposed theoretical analysis has guidance role for PTS system design.

  20. 78 FR 63185 - Waste Management System; Testing and Monitoring Activities; Update V of SW-846

    Science.gov (United States)

    2013-10-23

    ... readability or correct spelling or grammatical errors. ORCR has defined a ``significant change'' as a change... (LLOQ), relative standard error (RSE), initial demonstration of proficiency (IDP), etc.), each dated... typographical error was found for bis(2-chloroisopropyl) ether and was corrected to bis(2- chloro-1-methylethyl...

  1. Epidemiology of 3rd generation cephalosporin-resistant Escherichia coli on dairy farms

    Science.gov (United States)

    Dairy cattle have been identified as a reservoir for 3rd generation cephalosporin (3GC)-resistant Escherichia coli. We previously identified 3GC-resistant E. coli from manure composite samples of calves and cows in a survey of 80 farms in Pennsylvania. Resistant strains were most frequently isolated...

  2. Starting Young: Massachusetts Birth-3rd Grade Policies That Support Children's Literacy Development

    Science.gov (United States)

    Cook, Shayna; Bornfreund, Laura

    2015-01-01

    Massachusetts is one of a handful of states that is often recognized as a leader in public education, and for good reason. The Commonwealth consistently outperforms most states on national reading and math tests and often leads the pack in education innovations. "Starting Young: Massachusetts Birth-3rd Grade Policies that Support Children's…

  3. Malaria and Fetal Growth Alterations in the 3(rd) Trimester of Pregnancy

    DEFF Research Database (Denmark)

    Schmiegelow, Christentze; Minja, Daniel; Oesterholt, Mayke

    2013-01-01

    Pregnancy associated malaria is associated with decreased birth weight, but in-utero evaluation of fetal growth alterations is rarely performed. The objective of this study was to investigate malaria induced changes in fetal growth during the 3(rd) trimester using trans-abdominal ultrasound....

  4. A 3rd Order Low Power Switched Current Sigma-Delta Modulator

    DEFF Research Database (Denmark)

    Jørgensen, Ivan Herald Holger; Bogason, Gudmundur

    1996-01-01

    This paper presents a 3rd order switched current Sigma-Delta modulator. The Sigma-Delta modulator operates at a sampling rate of 600kHz and the signal band is 5.5kHz, i.e. an oversampling factor of 54.5 is used. Multiple input signals are used to reduce the internal signal swings which results...

  5. Using Food as a Tool to Teach Science to 3rd Grade Students in Appalachian Ohio

    Science.gov (United States)

    Duffrin, Melani W.; Hovland, Jana; Carraway-Stage, Virginia; McLeod, Sara; Duffrin, Christopher; Phillips, Sharon; Rivera, David; Saum, Diana; Johanson, George; Graham, Annette; Lee, Tammy; Bosse, Michael; Berryman, Darlene

    2010-01-01

    The Food, Math, and Science Teaching Enhancement Resource (FoodMASTER) Initiative is a compilation of programs aimed at using food as a tool to teach mathematics and science. In 2007 to 2008, a foods curriculum developed by professionals in nutrition and education was implemented in 10 3rd-grade classrooms in Appalachian Ohio; teachers in these…

  6. Participants to the 3rd HEP Information Resources Summit, 6-7 May 2009

    CERN Multimedia

    Fermilab, Photo Service

    2009-01-01

    The broad theme of the 3rd HEP Information Resources Summit was "Collaboration between Information Services." As HEP increasingly borders fields such as instrumentation and astrophysics, it was discussed what potential interrelationships and communication this group have to serve this broader research community seamlessly.

  7. Proceedings of the 3rd international workshop on socially-aware multimedia

    NARCIS (Netherlands)

    P.S. Cesar Garcia (Pablo Santiago); D.A. Shamma (David); M. Cooper; A. Kelliher

    2014-01-01

    htmlabstractIt is our pleasure to welcome you to the 3rd International Workshop on Socially-Aware Multimedia (SAM'14), which is held in conjunction with the International ACM Multimedia Conference 2014. The workshop provides, for the third consecutive year, an opportunity to explore

  8. Time use of Hellene 3rd and 4th graders during a school day

    NARCIS (Netherlands)

    Vleioras, Georgios

    2010-01-01

    Using data from the time diaries of 164 Hellene 3rd and 4th graders interviewed in their homes in March 2007, individual differences in time-use patterns were investigated. The participants rested for 9 hours 10 minutes, and spent 57.0%, 21.7%, and 5.0% of their waking time on school-related

  9. Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents.

    Science.gov (United States)

    Danso, Mogbekeloluwa O; van Drongelen, Vincent; Mulder, Aat; Gooris, Gert; van Smeden, Jeroen; El Ghalbzouri, Abdoelwaheb; Bouwstra, Joke A

    2015-02-01

    Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion of skin material from which only small fragments of skin can be harvested e.g. diseased skin. We evaluated whether 2(nd) and 3(rd) generation Ex-HSEs can also be generated from a single skin biopsy whilst maintaining the epidermal properties of 1(st) generation Ex-HSEs and native human skin. 2(nd) generation Ex-HSEs were produced by placing a biopsy from the 1(st) generation Ex-HSE onto a new dermal equivalent. Likewise, the 3(rd) generation Ex-HSEs were generated from a 2(nd) generation Ex-HSE biopsy. We show for the first time that Ex-HSEs can be passaged to the 2(nd) and 3(rd) generation and display similar epidermal morphology and expression of differentiation markers as in native human skin and 1(st) generation Ex-HSEs except for involucrin. The 2(nd) and 3(rd) generation Ex-HSEs also show many similarities with 1(st) generation Ex-HSEs in lipid properties e.g. presence of all lipid classes, similar fatty acid chain length distribution and lamellar lipid organization. However, some differences arise in increased level of hexagonal lateral packing and a change in ceramide profiling. The changes in specific lipid classes were also accompanied by changes in the expression of the enzymes responsible for their synthesis. The expansion of skin biopsies to the 2(nd) and 3(rd) generation Ex-HSEs could be a promising method to expand valuable epidermal tissue to analyze morphological and differentiation parameters in the native epidermis. Copyright © 2015 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.

  10. Making Classroom Assessment Work. Third Edition

    Science.gov (United States)

    Davies, Anne

    2011-01-01

    3rd Edition! When should we assess, and when should we evaluate? What might be the results of evaluating too early or too much? How do we know if we are evaluating the right things? How do we know what makes sense for the learner and for the course? These questions are at the heart of "Making Classroom Assessment Work." This book combines powerful…

  11. PREFACE: 3rd Workshop on Theory, Modelling and Computational Methods for Semiconductors (TMCSIII)

    Science.gov (United States)

    Califano, Marco; Migliorato, Max; Probert, Matt

    2012-05-01

    These conference proceedings contain the written papers of the contributions presented at the 3rd International Conference on Theory, Modelling and Computational Methods for Semiconductor materials and nanostructures. The conference was held at the School of Electronic and Electrical Engineering, University of Leeds, Leeds, UK on 18-20 January 2012. The previous conferences in this series took place in 2010 at St William's College, York and in 2008 at the University of Manchester, UK. The development of high-speed computer architectures is finally allowing the routine use of accurate methods for calculating the structural, thermodynamic, vibrational, optical and electronic properties of semiconductors and their hetero- and nano-structures. The scope of this conference embraces modelling, theory and the use of sophisticated computational tools in semiconductor science and technology, where there is substantial potential for time-saving in R&D. Theoretical approaches represented in this meeting included: Density Functional Theory, Tight Binding, Semiempirical Pseudopotential Methods, Effective Mass Models, Empirical Potential Methods and Multiscale Approaches. Topics included, but were not limited to: Optical and Transport Properties of Quantum Nanostructures including Colloids and Nanotubes, Plasmonics, Magnetic Semiconductors, Graphene, Lasers, Photonic Structures, Photovoltaic and Electronic Devices. This workshop ran for three days, with the objective of bringing together UK and international leading experts in the theoretical modelling of Group IV, III-V and II-VI semiconductors, as well as students, postdocs and early-career researchers. The first day focused on providing an introduction and overview of this vast field, aimed particularly at students, with several lectures given by recognised experts in various theoretical approaches. The following two days showcased some of the best theoretical research carried out in the UK in this field, with several

  12. The loss of student idealism in the 3rd-year clinical clerkships.

    Science.gov (United States)

    Griffith, C H; Wilson, J F

    2001-03-01

    The purpose of this study was to specify how student attitudes toward different types of patients and the profession change during clinical rotations. A questionnaire was given to all medical students prior to 3rd-year rotations regarding their attitudes toward the medical profession and patient types. It was given again after students completed their 16-week medicine-surgery clerkship. Eighty-eight of 96 students responded to pre- and posttests. Students became less idealistic toward two patient groups: the elderly and people with chronic pain. After clerkship, students believed a greater percentage of the elderly were demented (26% increasing to 35%, p = .09 and that a greater percentage of patients with chronic pain are drug seekers (15% increasing to 24%, p = .004). The authors conclude that in the 3rd year of medical school students become less idealistic toward elderly patients, those with chronic pain, and the profession.

  13. Correlates and Phenomenology of 1st and 3rd Person Memories

    Science.gov (United States)

    Sutin, Angelina R.; Robins, Richard W.

    2010-01-01

    The present research addressed fundamental questions about the visual perspective of autobiographical memories: Are stable personality characteristics associated with visual perspective? Does visual perspective influence the memory's phenomenological qualities? Participants in Study 1 (N = 1,684) completed individual-difference measures and indicated the perspective from which they generally retrieve memories. Participants in Study 2 (N = 706) retrieved a memory from their natural or manipulated perspective, rated its phenomenology, and completed the same individual-difference measures. Dissociation and anxiety were associated with 3rd person retrieval style; the Big Five personality traits were primarily unrelated to perspective. Compared to 3rd person memories, naturally-occurring 1st person memories were higher on Vividness, Coherence, Accessibility, Sensory Detail, Emotional Intensity, and Time Perspective and lower on Distancing; manipulating perspective eliminated these differences. Visual perspective is associated with clinically-relevant constructs and, although associated with the memory's phenomenology, perspective does not shape it. PMID:20665336

  14. The Settling of Mordovians in 3rd — Early 13th Centuries

    Directory of Open Access Journals (Sweden)

    Vikhlyaev Viktor I.

    2013-06-01

    Full Text Available Changes in the territorial extension of the Mordovians over the millennial period (the 3rd to the 13th centuries are discussed, and causes of the displacement are determined in the article. The three major periods are identified in the process: the 3rd to the 7th, the 8th to the 11th, and the 11th to the 13th centuries. The 3rd century marked the appearance of ancient burial grounds containing decorations that are ethnically typical of the Mordovians. The heyday of the ancient Mordovian culture in the late 3rd and first half of the 5th centuries was accompanied by the expansion of its territory to the north. By the late 7th – first half of the 8th century, two options of the ancient Mordovian culture were formed: the Erzya in the north and the Moksha in the south. In the 8th–11th centuries, the Moksha Mordvins settlement territory shifted to the north-west, which could be associated with the danger from the Khazar Khanate. The territory of the Erzya Mordvins settlement did not change in the period. In the 11th-13th centuries, and the Mordovian population fell into the spheres of influence of Kievan Rus and Volga Bulgaria. The struggle between these states, and later the princely strife in Russia, led to the resettlement of the Mordovians to safer areas: the Moksha moved to the Moksha-Vad river interfluve, while the Erzya relocated to the Tyosha river basin

  15. 2007: 3rd Jameson - D.I.T Faculty of Tourism and Food Cocktail Competition

    OpenAIRE

    Murphy, James Peter

    2007-01-01

    The 3rd Jameson - D.I.T Faculty of Tourism and Food Cocktail Competition took place on Thursday November 29th 2007, this initiative between the Faculty of Tourism and Food and Jameson offered over 60 hospitality and bartending students currently studying and working in the hospitality and licensed trade industries the opportunity to improve their skills in creative drinks mixing, in direct response to the growing demand for new cocktails and exciting new drinks to suit every season. Overall p...

  16. Sandstone columns of the 3rd Nile Cataract (Nubia, Northern Sudan)

    Czech Academy of Sciences Publication Activity Database

    Cílek, Václav; Adamovič, Jiří; Suková, L.

    2015-01-01

    Roč. 59, Supplement 1 (2015), s. 151-165 ISSN 0372-8854 Grant - others:Program interní podpory projektů mezinárodní spolupráce AV ČR(CZ) M100130902 Institutional support: RVO:67985831 Keywords : Nubian sandstone * columnar jointing * Voronoi fragmentation * 3rd Nile Cataract * Sudan Subject RIV: DB - Geology ; Mineralogy Impact factor: 1.103, year: 2015

  17. Using Photographs to Probe Students' Understanding of Physical Concepts: The Case of Newton's 3rd Law

    Science.gov (United States)

    Eshach, Haim

    2010-08-01

    The starting point of the present research is the following question: since we live in an age that makes increasing use of visual representations of all sorts, is not the visual representation a learner constructs a window into his/her understanding of what is or is not being learned? Following this direction of inquiry, the present preliminary study introduces and evaluates a novel technique for pinpointing learners’ misconceptions, namely, one that has learners create and interpret their own photographs (CIP). 27 high-school students and 26 pre-service teacher trainees were asked to assume the role of textbook designers and create a display—photograph plus attached verbal explanation—which, in their opinion, best depicted Newton’s 3rd law. Subsequent analysis of the participants’ photographs yielded the following six misconception categories: 3rd law not depicted; 3rd law depicts a sequence of events; tendency to introduce irrelevant entities in explanations; the word ‘reaction’ used colloquially; tendency to restrict the application of the third law to dynamic situations; and informal explanations in which the word “force” is absent. The findings indicate that, indeed, the CIP method can be effectively employed to elicit, detect, and investigate learners’ misconceptions. The CIP method joins the growing efforts to utilize the yet relatively untapped potential of visual tools for science education purposes.

  18. Recent advances on developing 3rd generation enzyme electrode for biosensor applications.

    Science.gov (United States)

    Das, Priyanki; Das, Madhuri; Chinnadayyala, Somasekhar R; Singha, Irom Manoj; Goswami, Pranab

    2016-05-15

    The electrochemical biosensor with enzyme as biorecognition element is traditionally pursued as an attractive research topic owing to their high commercial perspective in healthcare and environmental sectors. The research interest on the subject is sharply increased since the beginning of 21st century primarily, due to the concomitant increase in knowledge in the field of material science. The remarkable effects of many advance materials such as, conductive polymers and nanomaterials, were acknowledged in the developing efficient 3rd generation enzyme bioelectrodes which offer superior selectivity, sensitivity, reagent less detection, and label free fabrication of biosensors. The present review article compiles the major knowledge surfaced on the subject since its inception incorporating the key review and experimental papers published during the last decade which extensively cover the development on the redox enzyme based 3rd generation electrochemical biosensors. The tenet involved in the function of these direct electrochemistry based enzyme electrodes, their characterizations and various strategies reported so far for their development such as, nanofabrication, polymer based and reconstitution approaches are elucidated. In addition, the possible challenges and the future prospects in the development of efficient biosensors following this direct electrochemistry based principle are discussed. A comparative account on the design strategies and critical performance factors involved in the 3rd generation biosensors among some selected prominent works published on the subject during last decade have also been included in a tabular form for ready reference to the readers. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Preliminary Location Accuracy Assessments of 3rd Satellite of TH-1

    Directory of Open Access Journals (Sweden)

    WANG Renxiang

    2016-10-01

    Full Text Available The TH-1 satellite is the first stereo mapping transmission satellite in China, and the primary mission goal of the satellite is for topographic mapping at 1:50 000 scale and high-accuracy location without Ground Control Points (GCPs. 1st, 2nd satellites of TH-1 were launched on August 24, 2010, May 6, 2012, and 3rd satellite was launched on October 26, 2015. Now, three satellites of TH-1 are well operating on its orbit. After evaluation, the location accuracy of 1st satellite without GCPs is 10.3 m/5.7 m (horizontal accuracy/vertical elevation accuracy, and the location accuracy of 2nd is equivalent with 1st satellite. In this paper, the system overview of TH-1 and the key technical in ground image processing are introduced. Then, the preliminary location accuracy of 3rd is assessed. The results are shown using three routes images:the location accuracy of 3rd is higher than 2nd, and can realize high accuracy location without GCPs, in which the horizontal accuracy is 7.2 m, and the vertical elevation accuracy is 2.6 m.

  20. Foundational Skills to Support Reading for Understanding in Kindergarten through 3rd Grade. Educator's Practice Guide. NCEE 2016-4008

    Science.gov (United States)

    Foorman, Barbara; Beyler, Nicholas; Borradaile, Kelley; Coyne, Michael; Denton, Carolyn A.; Dimino, Joseph; Furgeson, Joshua; Hayes, Lynda; Henke, Juliette; Justice, Laura; Keating, Betsy; Lewis, Warnick; Sattar, Samina; Streke, Andrei; Wagner, Richard; Wissel, Sarah

    2016-01-01

    The goal of this practice guide is to offer educators specific, evidence-based recommendations for teaching foundational reading skills to students in kindergarten through 3rd grade. This guide is a companion to the existing practice guide, "Improving Reading Comprehension in Kindergarten Through 3rd Grade", and as a set, these guides…

  1. Extraction-Separation Performance and Dynamic Modeling of Orion Test Vehicles with Adams Simulation: 3rd Edition

    Science.gov (United States)

    Varela, Jose G.; Reddy, Satish; Moeller, Enrique; Anderson, Keith

    2017-01-01

    NASA's Orion Capsule Parachute Assembly System (CPAS) Project is now in the qualification phase of testing, and the Adams simulation has continued to evolve to model the complex dynamics experienced during the test article extraction and separation phases of flight. The ability to initiate tests near the upper altitude limit of the Orion parachute deployment envelope requires extractions from the aircraft at 35,000 ft-MSL. Engineering development phase testing of the Parachute Test Vehicle (PTV) carried by the Carriage Platform Separation System (CPSS) at altitude resulted in test support equipment hardware failures due to increased energy caused by higher true airspeeds. As a result, hardware modifications became a necessity requiring ground static testing of the textile components to be conducted and a new ground dynamic test of the extraction system to be devised. Force-displacement curves from static tests were incorporated into the Adams simulations, allowing prediction of loads, velocities and margins encountered during both flight and ground dynamic tests. The Adams simulation was then further refined by fine tuning the damping terms to match the peak loads recorded in the ground dynamic tests. The failure observed in flight testing was successfully replicated in ground testing and true safety margins of the textile components were revealed. A multi-loop energy modulator was then incorporated into the system level Adams simulation model and the effect on improving test margins be properly evaluated leading to high confidence ground verification testing of the final design solution.

  2. Improvements for international medicine donations: a review of the World Health Organization Guidelines for Medicine Donations, 3rd edition.

    Science.gov (United States)

    Cañigueral-Vila, Nuria; Chen, Jennifer C; Frenkel-Rorden, Lindsey; Laing, Richard

    2015-01-01

    Some humanitarian and development organizations respond to major natural disasters and emergencies by donating medicines. Many provide medicines on a routine basis to support health systems, particularly those run by Faith-Based Organizations. Although such donations can provide essential medicines to populations in great need, inappropriate donations also take place, with burdensome consequences. The World Health Organization (WHO) has developed the interagency Guidelines for Medicine Donations for use by donors and recipients in the context of emergency aid and international development assistance. Although comprehensive in nature and transferable to various emergency situations, adjustments to both content and formatting would improve this resource. Recommendations for the next version of these guidelines include: specific wording and consistent formatting; definition of who is a recipient, clear distinction between acute and long-term emergencies, and proper donation procedures pertaining to each; inclusion of visual aides such as flowcharts, checklists, and photos; and improving the citations system.

  3. Republished: Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition

    Directory of Open Access Journals (Sweden)

    Vikram Patel

    2016-01-01

    Full Text Available The burden of mental, neurological, and substance use (MNS disorders increased by 41% between 1990 and 2010 and now accounts for one in every 10 lost years of health globally. This sobering statistic does not take into account the substantial excess mortality associated with these disorders or the social and economic consequences of MNS disorders on affected persons, their caregivers, and society. A wide variety of effective interventions, including drugs, psychological treatments, and social interventions, can prevent and treat MNS disorders. At the population-level platform of service delivery, best practices include legislative measures to restrict access to means of self-harm or suicide and to reduce the availability of and demand for alcohol. At the community-level platform, best practices include life-skills training in schools to build social and emotional competencies. At the health-care-level platform, we identify three delivery channels. Two of these delivery channels are especially relevant from a public health perspective: self-management (eg, web-based psychological therapy for depression and anxiety disorders and primary care and community outreach (eg, non-specialist health worker delivering psychological and pharmacological management of selected disorders. The third delivery channel, hospital care, which includes specialist services for MNS disorders and first-level hospitals providing other types of services (such as general medicine, HIV, or paediatric care, play an important part for a smaller proportion of cases with severe, refractory, or emergency presentations and for the integration of mental health care in other health-care channels, respectively. The costs of providing a significantly scaled up package of specified cost-effective interventions for prioritised MNS disorders in low-income and lower-middle-income countries is estimated at US$3-4 per head of population per year. Since a substantial proportion of MNS disorders run a chronic and disabling course and adversely affect household welfare, intervention costs should largely be met by government through increased resource allocation and financial protection measures (rather than leaving households to pay out-of-pocket. Moreover, a policy of moving towards universal public finance can also be expected to lead to a far more equitable allocation of public health resources across income groups. Despite this evidence, less than 1% of development assistance for health and government spending on health in low-income and middle-income countries is allocated to the care of people with these disorders. Achieving the health gains associated with prioritised interventions will require not just financial resources, but committed and sustained efforts to address a range of other barriers (such as paucity of human resources, weak governance, and stigma. Ultimately, the goal is to massively increase opportunities for people with MNS disorders to access services without the prospect of discrimination or impoverishment and with the hope of attaining optimal health and social outcomes.

  4. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.

    Science.gov (United States)

    Patel, Vikram; Chisholm, Dan; Parikh, Rachana; Charlson, Fiona J; Degenhardt, Louisa; Dua, Tarun; Ferrari, Alize J; Hyman, Steve; Laxminarayan, Ramanan; Levin, Carol; Lund, Crick; Medina Mora, María Elena; Petersen, Inge; Scott, James; Shidhaye, Rahul; Vijayakumar, Lakshmi; Thornicroft, Graham; Whiteford, Harvey

    2016-04-16

    The burden of mental, neurological, and substance use (MNS) disorders increased by 41% between 1990 and 2010 and now accounts for one in every 10 lost years of health globally. This sobering statistic does not take into account the substantial excess mortality associated with these disorders or the social and economic consequences of MNS disorders on affected persons, their caregivers, and society. A wide variety of effective interventions, including drugs, psychological treatments, and social interventions, can prevent and treat MNS disorders. At the population-level platform of service delivery, best practices include legislative measures to restrict access to means of self-harm or suicide and to reduce the availability of and demand for alcohol. At the community-level platform, best practices include life-skills training in schools to build social and emotional competencies. At the health-care-level platform, we identify three delivery channels. Two of these delivery channels are especially relevant from a public health perspective: self-management (eg, web-based psychological therapy for depression and anxiety disorders) and primary care and community outreach (eg, non-specialist health worker delivering psychological and pharmacological management of selected disorders). The third delivery channel, hospital care, which includes specialist services for MNS disorders and first-level hospitals providing other types of services (such as general medicine, HIV, or paediatric care), play an important part for a smaller proportion of cases with severe, refractory, or emergency presentations and for the integration of mental health care in other health-care channels, respectively. The costs of providing a significantly scaled up package of specified cost-effective interventions for prioritised MNS disorders in low-income and lower-middle-income countries is estimated at US$3-4 per head of population per year. Since a substantial proportion of MNS disorders run a chronic and disabling course and adversely affect household welfare, intervention costs should largely be met by government through increased resource allocation and financial protection measures (rather than leaving households to pay out-of-pocket). Moreover, a policy of moving towards universal public finance can also be expected to lead to a far more equitable allocation of public health resources across income groups. Despite this evidence, less than 1% of development assistance for health and government spending on health in low-income and middle-income countries is allocated to the care of people with these disorders. Achieving the health gains associated with prioritised interventions will require not just financial resources, but committed and sustained efforts to address a range of other barriers (such as paucity of human resources, weak governance, and stigma). Ultimately, the goal is to massively increase opportunities for people with MNS disorders to access services without the prospect of discrimination or impoverishment and with the hope of attaining optimal health and social outcomes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd Edition.

    Science.gov (United States)

    Bundy, Donald A P; de Silva, Nilanthi; Horton, Susan; Patton, George C; Schultz, Linda; Jamison, Dean T

    2017-11-16

    The realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence. Focus on the first 1000 days is an essential but insufficient investment. Intervention is also required in three later phases: the middle childhood growth and consolidation phase (5-9 years), when infection and malnutrition constrain growth, and mortality is higher than previously recognised; the adolescent growth spurt (10-14 years), when substantial changes place commensurate demands on good diet and health; and the adolescent phase of growth and consolidation (15-19 years), when new responses are needed to support brain maturation, intense social engagement, and emotional control. Two cost-efficient packages, one delivered through schools and one focusing on later adolescence, would provide phase-specific support across the life cycle, securing the gains of investment in the first 1000 days, enabling substantial catch-up from early growth failure, and leveraging improved learning from concomitant education investments. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. TIES for Dummies 3rd Edition (Technology Identification, Evaluation, and Selection) Basic how to's to implement the TIES method

    Science.gov (United States)

    Kirby, Michelle R.

    2002-01-01

    The TIES method is a forecasting environment whereby the decision-maker has the ability to easily assess and trade-off the impact of various technologies without sophisticated and time-consuming mathematical formulations. TIES provides a methodical approach where technically feasible alternatives can be identified with accuracy and speed to reduce design cycle time, and subsequently, life cycle costs, and was achieved through the use of various probabilistic methods, such as Response Surface Methodology and Monte Carlo Simulations. Furthermore, structured and systematic techniques are utilized from other fields to identify possible concepts and evaluation criteria by which comparisons can be made. This objective is achieved by employing the use of Morphological Matrices and Multi-Attribute Decision Making techniques. Through the execution of each step, a family of design alternatives for a given set of customer requirements can be identified and assessed subjectively or objectively. This methodology allows for more information (knowledge) to be brought into the earlier phases of the design process and will have direct implications on the affordability of the system. The increased knowledge allows for optimum allocation of company resources and quantitative justification for program decisions. Finally, the TIES method provided novel results and quantitative justification to facilitate decision making in the early stages of design so as to produce affordable and quality products.

  7. Living Tomorrow... An Inquiry into the Preparation of Young People for Working Life in Europe. 3rd Edition.

    Science.gov (United States)

    Deforge, Ives

    Technological advances have created changes in working life. Automation displaces more workers than the service industry can absorb. The jobs that are left are often downgraded from the complexity they have formerly enjoyed. As society becomes more and more automated, unemployment becomes structural. How do we prepare young people for the jobs of…

  8. FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

    Science.gov (United States)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2013-10-01

    Conference logo This volume of Journal of Physics: Conference Series is dedicated to the scientific contributions presented during the 3rd International Workshop on New Computational Methods for Inverse Problems, NCMIP 2013 (http://www.farman.ens-cachan.fr/NCMIP_2013.html). This workshop took place at Ecole Normale Supérieure de Cachan, in Cachan, France, on 22 May 2013, at the initiative of Institut Farman. The prior editions of NCMIP also took place in Cachan, France, firstly within the scope of the ValueTools Conference, in May 2011 (http://www.ncmip.org/2011/), and secondly at the initiative of Institut Farman, in May 2012 (http://www.farman.ens-cachan.fr/NCMIP_2012.html). The NCMIP Workshop focused on recent advances in the resolution of inverse problems. Indeed inverse problems appear in numerous scientific areas such as geophysics, biological and medical imaging, material and structure characterization, electrical, mechanical and civil engineering, and finances. The resolution of inverse problems consists of estimating the parameters of the observed system or structure from data collected by an instrumental sensing or imaging device. Its success firstly requires the collection of relevant observation data. It also requires accurate models describing the physical interactions between the instrumental device and the observed system, as well as the intrinsic properties of the solution itself. Finally, it requires the design of robust, accurate and efficient inversion algorithms. Advanced sensor arrays and imaging devices provide high rate and high volume data; in this context, the efficient resolution of the inverse problem requires the joint development of new models and inversion methods, taking computational and implementation aspects into account. During this one-day workshop, researchers had the opportunity to bring to light and share new techniques and results in the field of inverse problems. The topics of the workshop were: algorithms and computational

  9. Summary of the 3rd workshop on the reduced-moderation water reactor

    Energy Technology Data Exchange (ETDEWEB)

    Ishikawa, Nobuyuki; Nakatsuka, Tohru; Iwamura, Takamichi [eds.

    2000-06-01

    The research activities of a Reduced-Moderation Water Reactor (RMWR) are being performed for a development of the next generation water-cooled reactor. A workshop on the RMWR was held on March 3rd 2000 aiming to exchange information between JAERI and other organizations such as universities, laboratories, utilities and vendors. This report summarizes the contents of lectures and discussions on the workshop. The 1st workshop was held on March 1998 focusing on the review of the research activities and future research plan. The succeeding 2nd workshop was held on March 1999 focusing on the topics of the plutonium utilization in water-cooled reactors. The 3rd workshop was held on March 3rd 2000, which was attended by 77 participants. The workshop began with a lecture titled 'Recent Situation Related to Reduced-Moderation Water Reactor (RMWR)', followed by 'Program on MOX Fuel Utilization in Light Water Reactors' which is the mainstream scenario of plutonium utilization by utilities, and 'Feasibility Studies on Commercialized Fast Breeder Reactor Cycle System' mainly conducted by Japan Nuclear Cycle Development Institute (JNC). Also, following lectures were given as the recent research activities in JAERI: 'Progress in Design Study on Reduced-Moderation Water Reactors', 'Long-Term Scenarios of Power Reactors and Fuel Cycle Development and the Role of Reduced Moderation Water Reactors', 'Experimental and Analytical Study on Thermal Hydraulics' and Reactor Physics Experiment Plan using TCA'. At the end of the workshop, a general discussion was performed about the research and development of the RMWR. This report includes the original papers presented at the workshop and summaries of the questions and answers for each lecture and general discussion, as well as presentation viewgraphs, program and participant list as appendixes. The 7 of the presented papers are indexed individually. (J.P.N.)

  10. ESO-ESMO 3rd international consensus guidelines for breast cancer in young women (BCY3).

    Science.gov (United States)

    Paluch-Shimon, Shani; Pagani, Olivia; Partridge, Ann H; Abulkhair, Omalkhair; Cardoso, Maria-João; Dent, Rebecca Alexandra; Gelmon, Karen; Gentilini, Oreste; Harbeck, Nadia; Margulies, Anita; Meirow, Dror; Pruneri, Giancarlo; Senkus, Elzbieta; Spanic, Tanja; Sutliff, Medha; Travado, Luzia; Peccatori, Fedro; Cardoso, Fatima

    2017-10-01

    The 3rd International Consensus Conference for Breast Cancer in Young Women (BCY3) took place in November 2016, in Lugano, Switzerland organized by the European School of Oncology (ESO) and the European Society of Medical Oncologists (ESMO). Consensus recommendations for the management of breast cancer in young women were updated from BCY2 with incorporation of new evidence to inform the guidelines, and areas of research priorities were identified. This manuscript summarizes the ESO-ESMO international consensus recommendations, which are also endorsed by the European Society of Breast Specialists (EUSOMA). Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. 3rd International Symposium on Big Data and Cloud Computing Challenges

    CERN Document Server

    Neelanarayanan, V

    2016-01-01

    This proceedings volume contains selected papers that were presented in the 3rd International Symposium on Big data and Cloud Computing Challenges, 2016 held at VIT University, India on March 10 and 11. New research issues, challenges and opportunities shaping the future agenda in the field of Big Data and Cloud Computing are identified and presented throughout the book, which is intended for researchers, scholars, students, software developers and practitioners working at the forefront in their field. This book acts as a platform for exchanging ideas, setting questions for discussion, and sharing the experience in Big Data and Cloud Computing domain.

  12. Design of a 3rd order micro power switched current ΣΔ-modulator

    DEFF Research Database (Denmark)

    Jørgensen, Ivan Harald Holger; Bogason, Gudmundur

    1996-01-01

    This paper reports the design of a 3rd order switched current-ΣΔ-modulator. The modulator is design to have a SNR of 80 dB with a signal bandwidth of fb=6 kHz. The oversampling ratio is R=90 and the sampling frequency fs=1.08 MHz. Multiple input signals are used to reduce the internal signal swings......W. The supply voltage is VDD=2.7 V. A new methology is presented that allows for optimization of SI circuits for minimum power consumption with respect to process tolerances...

  13. 3rd IFToMM Symposium on Mechanism Design for Robotics

    CERN Document Server

    Ceccarelli, Marco

    2015-01-01

    This volume contains the Proceedings of the 3rd IFToMM Symposium on Mechanism Design for Robotics, held in Aalborg, Denmark, 2-4 June, 2015. The book contains papers on recent advances in the design of mechanisms and their robotic applications. It treats the following topics: mechanism design, mechanics of robots, parallel manipulators, actuators and their control, linkage and industrial manipulators, innovative mechanisms/robots and their applications, among others. The book can be used by researchers and engineers in the relevant areas of mechanisms, machines and robotics.

  14. Virtual Visit to the ATLAS Control Room by 3rd Gymnasium in Volos

    CERN Multimedia

    2013-01-01

    The city of Volos, situated at the centre of the Greek mainland, will be hosting the 7th International Olympiad on Astronomy and Astrophysics this summer. In this context, and with support of PATHWAY and Discover the COSMOS projects, Volos` science education community is organising several pre-events aimed at bringing the world`s biggest experiments in science closer to students - the scientists of tomorrow. Junior high school students from the 3rd Gymnasium in Volos will have the unique opportunity to visit the ATLAS control room on 29th of March.

  15. 3rd International Conference on Modelling, Computation and Optimization in Information Systems and Management Sciences

    CERN Document Server

    Dinh, Tao; Nguyen, Ngoc

    2015-01-01

    This proceedings set contains 85 selected full papers presented at the 3rd International Conference on Modelling, Computation and Optimization in Information Systems and Management Sciences - MCO 2015, held on May 11–13, 2015 at Lorraine University, France. The present part I of the 2 volume set includes articles devoted to Combinatorial optimization and applications, DC programming and DCA: thirty years of Developments, Dynamic Optimization, Modelling and Optimization in financial engineering, Multiobjective programming, Numerical Optimization, Spline Approximation and Optimization, as well as Variational Principles and Applications

  16. Umbilical hypercoiling in 2nd- and 3rd-trimester intrauterine fetal death.

    Science.gov (United States)

    Dutman, Annemiek C; Nikkels, Peter G J

    2015-01-01

    Cases of unexplained intrauterine fetal death (IUFD) can be reduced by full placental examination, with or without autopsy. Determination of the umbilical coiling index (UCI) is considered to be a part of full placental examination. Umbilical hypercoiling (UCI above 0.30 coils/cm) is associated with IUFD. In a large retrospective study, we found an incidence of 18% umbilical hypercoiling in IUFD. We explored the association between umbilical hypercoiling and 2nd- and 3rd-trimester IUFD in 77 cases. There was a significant negative correlation between the UCI and gestational age of IUFD (PUCI should be part of the routine placental examination of cases of IUFD.

  17. Teaching Newton's 3rd law of motion using learning by design approach

    Science.gov (United States)

    Aquino, Jiezel G.; Caliguid, Mariel P.; Buan, Amelia T.; Magsayod, Joy R.; Lahoylahoy, Myrna E.

    2018-01-01

    This paper presents the process and implementation of Learning by Design Approach in teaching Newton's 3rd Law of Motion. A lesson activity from integrative STEM education was adapted, modified and enhanced through pilot testing. After revisions, the implementation was done to one class. The respondent's prior knowledge was first assessed by a pretest. PPIT (present the scenario, plan, implement and test) was the framework followed in the implementation of Learning by Design. Worksheets were then utilized to measure their conceptual understanding and perception. A score guide was also used to evaluate the student's output. Paired t-test analysis showed that there is a significant difference in the pretest and posttest achievement scores. This implies that the performance of the students have improved during the implementation of the Learning by Design. The Analysis of variance also depicts that the low, average and high benefited in the Learning by Design approach. The results of this study suggests that Learning by Design is an effective approach in teaching Newton's 3rd Law of Motion and thus be used in a Science classroom.

  18. The Third International Genomic Medicine Conference (3rd IGMC, 2015: overall activities and outcome highlights

    Directory of Open Access Journals (Sweden)

    Muhammad Abu-Elmagd

    2016-10-01

    Full Text Available Abstract The Third International Genomic Medicine Conference (3rd IGMC was organised by the Centre of Excellence in Genomic Medicine Research (CEGMR at the King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia (KSA. This conference is a continuation of a series of meetings, which began with the first International Genomic Medicine Conference (1st IGMC, 2011 followed by the second International Genomic Medicine Conference (2nd IGMC, 2013. The 3rd IGMC meeting presented as a timely opportunity to bring scientists from across the world to gather, discuss, and exchange recent advances in the field of genomics and genetics in general as well as practical information on using these new technologies in different basic and clinical applications. The meeting undoubtedly inspired young male and female Saudi researchers, who attended the conference in large numbers, as evidenced by the oversubscribed oral and poster presentations. The conference also witnessed the launch of the first content for npj Genomic Medicine, a high quality new journal was established in partnership by CEGMR with Springer Nature and published as part of the Nature Partner Journal series. Here, we present a brief summary report of the 2-day meeting including highlights from the oral presentations, poster presentations, workshops, poster prize-winners and comments from the distinguished scientists.

  19. Monitoring of the North Korea's 3rd Nuclear Test using Regional Seismic Network

    Science.gov (United States)

    Chi, H.; Kim, G.; Shin, J.; Kim, T.; Che, I.

    2013-12-01

    Through seismic data exchange with China, Russia and Japan, KIGAM could precisely monitor for the more recent North Korea nuclear test with full azimuthal coverage from the test site. The high coherence of collocated stations' seismograms to the previous two events allowed us to infer the tiny difference in the source locations. By estimating relative location to the 3 event s with minimizing 1st P wave arrival time differences, the 3rd test's location was determined to be at the latitude of 41.275N, longitude of 129.064E which is 400 meter south from the 2009 test. A network averaged body wave magnitude, mb(Pn) was evaluated as 4.9, which varies with directional location of stations widely from 4.2 to 5.5. A network averaged surface wave magnitude was estimated to be 3.9. Moment tensor inversion with data from the regional stations gives us source analysis results with high fidelity. The result shows the 3rd test had a very large isotropic component, indicative of an explosion source, similar inversion results were also obtained from previous 2 tests KIGAM evaluated the yield of the test to be 6~7kTon(×3 kTon) by combining Magnitude-Yield Relationships.

  20. 'A good midwife stands out': 3rd year midwifery students' views.

    Science.gov (United States)

    Carolan, Mary

    2013-02-01

    the midwifery workforce in Australia is ageing and predominantly part-time. There is considerable interest in the induction and retention of new midwives in the profession. this study was undertaken to explore 3rd year students' views of the good midwife. It was anticipated that student views would show evidence of early transition and socialisation into the profession. qualitative thematic analysis. Melbourne, Australia all completing midwifery students, in 2010, were invited to participate (n=31). three broad themes emerged from the analysis: (1) a skilled practitioner; (2) a caring and compassionate individual; and (3) beyond the call of duty: passion and enthusiasm for midwifery. it was evident that 3rd year students' views of the good midwife were becoming aligned with the views of qualified midwives. Students also acknowledged the importance of safe practice at the same time as supporting women to make decisions. However, their intense passion and enthusiasm for midwifery practice may make them vulnerable to disappointment with the profession. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Formal faculty observation and assessment of bedside skills for 3rd-year neurology clerks.

    Science.gov (United States)

    Thompson Stone, Robert; Mooney, Christopher; Wexler, Erika; Mink, Jonathan; Post, Jennifer; Jozefowicz, Ralph F

    2016-11-22

    To evaluate the feasibility and utility of instituting a formalized bedside skills evaluation (BSE) for 3rd-year medical students on the neurology clerkship. A neurologic BSE was developed for 3rd-year neurology clerks at the University of Rochester for the 2012-2014 academic years. Faculty directly observed 189 students completing a full history and neurologic examination on real inpatients. Mock grades were calculated utilizing the BSE in the final grade, and number of students with a grade difference was determined when compared to true grade. Correlation was explored between the BSE and clinical scores, National Board of Medical Examiners (NBME) scores, case complexity, and true final grades. A survey was administered to students to assess their clinical skills exposure and the usefulness of the BSE. Faculty completed and submitted a BSE form for 88.3% of students. There was a mock final grade change for 13.2% of students. Correlation coefficients between BSE score and clinical score/NBME score were 0.36 and 0.35, respectively. A statistically significant effect of BSE was found on final clerkship grade (F2,186 = 31.9, p neurology clerkship was feasible. Low correlation between BSE score and other evaluations indicated a unique measurement to contribute to student grade. Using real patients with differing case complexity did not alter the grade. © 2016 American Academy of Neurology.

  2. PREFACE: 3rd International Symposium on Functional Materials 2009 (ISFM 2009) 3rd International Symposium on Functional Materials 2009 (ISFM 2009)

    Science.gov (United States)

    Kiwon, Kim; Li, Lu; Taehyun, Nam; Jouhyeon, Ahn

    2010-05-01

    The 3rd International Symposium on Functional Materials 2009 (ISFM 2009) and its preconference, Advances in Functional Materials 2009 (AFM 2009), were successfully held in the Republic of Korea from 15-18 June 2009 and in the People's Republic of China from 8-12 June 2009, respectively. The two conferences attracted over 300 oral and poster presentations from over 12 countries including Australia, Canada, China, Germany, Japan, India, Israel, Korea, The Netherlands, Thailand, the UK and the USA. In the two conferences, eight keynote lectures were delivered by S Miyazaki, S A Akbar, D J Singh, C Suryanarayana, M~Greenblatt, H Zhang, T Sato and J Ding. This topical issue of Physica Scripta contains papers presented at the ISFM 2009 and AFM 2009. Keyan Li from Dalian University, People's Republic of China, presents some empirical formulae to estimate the elastic moduli of rocksalt-, zincblende- and chalcopyrite-structured crystals, on the basis of electronegativities of bonded atoms in the crystallographic frame. Min-Jung Kim from Hanyang University, Korea, reports on the preparation and characterization of carboxyl functionalization of magnetite nanoparticles for oligonucleotide immobilization. F Yan from the National University of Singapore studies the fabrication of Bi(Fe0.5Sc0.5)O3-PbTiO3 (BSF-PT) thin films by pulsed laser deposition, and the enhanced magnetic moment with respect to BiFeO3-PbTiO3. Dong-Gil Lee from Pusan National University, Korea, reports on the sterilization of enteropathogenic Escherichia coli using nanofiber TiO2 films prepared by the electrostatic spray method. Sang-Eun Park from the Korea Institute of Science and Technology reports on the study of encapsulated Fe3O4 nanoparticles with a silica thin layer with a reversible capacity of about 363 mAhg-1. Other researchers report on many other exiting achievements in the fields of ferromagnetic materials, magneto-optical materials, thermoelectric materials, shape memory materials, fuel-cell and

  3. 3rd International Conference on Modelling and Management of Engineering Processes

    CERN Document Server

    Gericke, Kilian; Szélig, Nikoletta; Vajna, Sándor

    2015-01-01

    Innovative processes for the development of products and services are more and more considered as an organisational capability, which is recognised to be increasingly important for business success in today’s competitive environment. However, management and academia need a more profound understanding of these processes in order to develop improved management approaches to exploit business potentials. This book contains the proceedings of the 3rd International Conference on Modelling and Management of Engineering Processes (MMEP2013) held in Magdeburg, Germany, in November 2013. It includes contributions from international leading researchers in the fields of process modelling and process management. The conference topics were recent trends in modelling and management of engineering processes, potential synergies between different modelling approaches, future challenges for the management of engineering processes as well as future research in these areas.

  4. Do the smart get smarter? Development of fluid and crystallized intelligence in 3rd grade

    DEFF Research Database (Denmark)

    Schroeders, Ulrich; Schipolowski, Stefan; Zettler, Ingo

    2016-01-01

    . In this study, 1,102 elementary students in 3rd Grade worked on two versions of the Berlin Test of Fluid and Crystallized Intelligence at two time points with an interval of five months. Beside the question of how initial state and growth are related (Matthew vs. compensation effect), we considered performance......There are conflicting theoretical assumptions about the development of general cognitive abilities in childhood: On the one hand, a higher initial level of abilities has been suggested to facilitate ability improvement, for example, prior knowledge fosters the acquisition of new knowledge (Matthew...... and content-related reasons are discussed to account for the unexpectedly negligible effects found for most of the covariates....

  5. 3rd international KES conference on Smart Education and Smart e-Learning

    CERN Document Server

    Howlett, Robert; Jain, Lakhmi

    2016-01-01

    This book contains the contributions presented at the 3rd international KES conference on Smart Education and Smart e-Learning, which took place in Puerto de la Cruz, Tenerife, Spain, June 15-17, 2016. It contains a total of 56 peer-reviewed book chapters that are grouped into several parts: Part 1 - Smart University: Conceptual Modeling, Part 2 – Smart Education: Research and Case Studies, Part 3 – Smart e-Learning, Part 4 – Smart Education: Software and Hardware Systems, and Part 5 – Smart Technology as a Resource to Improve Education and Professional Training. We believe that the book will serve as a useful source of research data and valuable information for faculty, scholars, Ph.D. students, administrators, and practitioners - those who are interested in innovative areas of smart education and smart e-learning. .

  6. 3rd International Doctoral Symposium on Applied Computation and Security Systems

    CERN Document Server

    Saeed, Khalid; Cortesi, Agostino; Chaki, Nabendu

    2017-01-01

    This book presents extended versions of papers originally presented and discussed at the 3rd International Doctoral Symposium on Applied Computation and Security Systems (ACSS 2016) held from August 12 to 14, 2016 in Kolkata, India. The symposium was jointly organized by the AGH University of Science & Technology, Cracow, Poland; Ca’ Foscari University, Venice, Italy; and the University of Calcutta, India. The book is divided into two volumes, Volumes 3 and 4, and presents dissertation works in the areas of Image Processing, Biometrics-based Authentication, Soft Computing, Data Mining, Next-Generation Networking and Network Security, Remote Healthcare, Communications, Embedded Systems, Software Engineering and Service Engineering. The first two volumes of the book published the works presented at the ACSS 2015, which was held from May 23 to 25, 2015 in Kolkata, India.

  7. Passive solar progress: a simplified guide to the 3rd national passive solar conference

    Energy Technology Data Exchange (ETDEWEB)

    Miller, H.; Howell, Y.; Richards, D.

    1980-10-01

    Some of the concepts and practices that have come to be known as passive solar heating and cooling are introduced, and a current picture of the field is presented. Much of the material presented is derived from papers given at the 3rd National Passive Solar Conference held in San Jose, California in January 1979 and sponsored by the US Department of Energy. Extracts and data from these papers have been integrated in the text with explanatory and descriptive material. In this way, it is attempted to present technical information in an introductory context. Topics include design considerations, passive and hybrid systems and applications, sizing methods and performance prediction, and implementation issues. A glossary is included. (WHK)

  8. Relation between physical activity and academic performance in 3rd-year secondary education students.

    Science.gov (United States)

    Morales, José; Pellicer-Chenoll, Maite; García-Masso, Xavier; Gomis, Manuel; González, Luis-Millán

    2011-10-01

    The main aim of this study was to analyze the relationship between the amount of physical activity and academic performance in 3rd-year secondary education students. The sample was taken from three secondary schools in the area of Barcelona. 284 students (158 girls, 126 boys) with an average age of 14.7 yr. participated. The International Physical Activity Questionnaire was used by students to self-report their amount of physical activity. Students' academic records were obtained for comparisons. Results showed that there was a linear relationship between academic performance and physical activity; nevertheless, there was a trend to stronger correlation when modeling the relationship between these variables with a quadratic equation. Further research should focus on whether academic performance and physical activity might be better explained with a second-order equation.

  9. Nonlinear Dynamics of Memristor Based 2nd and 3rd Order Oscillators

    KAUST Repository

    Talukdar, Abdul Hafiz

    2011-05-01

    Exceptional behaviours of Memristor are illustrated in Memristor based second order (Wien oscillator) and third order (phase shift oscillator) oscillator systems in this Thesis. Conventional concepts about sustained oscillation have been argued by demonstrating the possibility of sustained oscillation with oscillating resistance and dynamic poles. Mathematical models are also proposed for analysis and simulations have been presented to support the surprising characteristics of the Memristor based oscillator systems. This thesis also describes a comparative study among the Wien family oscillators with one Memristor. In case of phase shift oscillator, one Memristor and three Memristors systems are illustrated and compared to generalize the nonlinear dynamics observed for both 2nd order and 3rd order system. Detail explanations are provided with analytical models to simplify the unconventional properties of Memristor based oscillatory systems.

  10. 3rd International Summer School Nanotechnology : From Fundamental Research to Innovations

    CERN Document Server

    Yatsenko, Leonid

    2015-01-01

    This book highlights the most recent advances in nanoscience from leading researchers in Ukraine, Europe, and beyond.  It features contributions from participants of the 3rd International Summer School “Nanotechnology: From Fundamental Research to Innovations,” held in Yaremche, Ukraine on August 23-26, 2014 and of the 2nd International NANO-2014 Conference, held in Lviv, Ukraine on August 27-30, 2014.  These events took place within the framework of the European Commission FP7 project Nanotwinning, and were organized jointly by the Institute of Physics of the National Academy of Sciences of Ukraine, University of Tartu (Estonia), University of Turin (Italy), and Pierre and Marie Curie University (France).  Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key results in the areas of nanocomposites and nanomaterials, nanostructured surfaces, microscopy of nano-objects, nano-optics and nanophotonics, nanoplasmonics, nanochemistry, na...

  11. Idaho National Laboratory Quarterly Occurrence Analysis - 3rd Quarter FY-2016

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Lisbeth Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 73 reportable events (23 from the 3rd Qtr FY-16 and 50 from the prior three reporting quarters), as well as 45 other issue reports (including events found to be not reportable and Significant Category A and B conditions) identified at INL during the past 12 months (16 from this quarter and 29 from the prior three quarters).

  12. 3rd Sino-German Conference “Underground Storage of CO2 and Energy”

    CERN Document Server

    Xie, Heping; Were, Patrick

    2013-01-01

    Anthropogenic greenhouse gas emissions, energy security and sustainability are three of the greatest contemporary global challenges today. This year the Sino-German Cooperation Group “Underground Storage of CO2 and Energy”, is meeting on the 21-23 May 2013 for the second time in Goslar, Germany, to convene its 3rd Sino-German conference on the theme “Clean Energy Systems in the Subsurface: Production, Storage and Conversion”.   This volume is a collection of diverse quality scientific works from different perspectives elucidating on the current developments in CO2 geologic sequestration research to reduce greenhouse emissions including measures to monitor surface leakage, groundwater quality and the integrity of caprock, while ensuring a sufficient supply of clean energy. The contributions herein have been structured into 6 major thematic research themes: Integrated Energy and Environmental Utilization of Geo-reservoirs: Law, Risk Management & Monitoring CO2 for Enhanced Gas and Oil Recovery, Coa...

  13. The Perception of Entrepreneurial and 3rd Generation University in Turkey

    Directory of Open Access Journals (Sweden)

    Deniz Zungun

    2016-07-01

    Full Text Available Increased competition caused by globalization has led to philosophical changes in private and public businesses. This situation has affected educational institutions and they have needed dynamic, innovator and transformational tools in order to survive in competitive environment. The universities defined as �3rd Generation Universities� need commercialization, network among universities, close co-operation among institutions and entrepreneurship as well as intellectual and innovative changes. In this regard, the aim of the research is formed by the analysis of �Entrepreneur University� concept from the perspective of the academicians that served at managerial positions at the universities in Turkey. The research is limited to the opinions of the academicians that served at top, middle and lower management at randomly chosen 20 universities.

  14. John D. Rockefeller 3rd, statesman and founder of the Population Council.

    Science.gov (United States)

    Dunlop, J

    2000-01-01

    This article presents a profile of John D. Rockefeller 3rd, statesman and founder of the Population Council. It is noted that Rockefeller took a broad view of population control as a means to address poverty and economic development rather than as an end in itself. In 1952 he initiated the convocation of the Conference on Population Problems held in Williamsburg, Virginia. The discussion focused on food supply, industrial development, depletion of natural resources, and political instability resulting from unchecked population growth. In 1967, Rockefeller initiated, lobbied for, and finally achieved a World Leaders' Statement signed by 30 heads of state including US President Lyndon Johnson. The document drew attention to population growth as a world problem and engendered political support for family planning as a solution. After 3 years the Commission on Population Growth and the American Future was established, and Rockefeller was made its chairman. Several issues were debated, including more safer fertility control and the legalization of abortion.

  15. 3rd International Asia Conference on Informatics in Control, Automation and Robotics

    CERN Document Server

    Informatics in Control, Automation and Robotics

    2012-01-01

    Session 2 includes 110 papers selected from 2011 3rd International Asia Conference on Informatics in Control, Automation and Robotics (CAR 2011), held on December 24-25, 2011, Shenzhen, China.   As we all know, the ever growing technology in robotics and automation will help build a better human society. This session will provide a unique opportunity for the academic and industrial communities to address new challenges, share solutions, and discuss research directions for the future. Robotics research emphasizes intelligence and adaptability to cope with unstructured environments. Automation research emphasizes efficiency, productivity, quality, and reliability, focusing on systems that operate autonomously. The main focus of this session is on the autonomous acquisition of semantic information in intelligent robots and systems, as well as the use of semantic knowledge to guide further acquisition of information.

  16. 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Koziel, Slawomir; Kacprzyk, Janusz; Leifsson, Leifur; Ören, Tuncer

    2015-01-01

    This book includes extended and revised versions of a set of selected papers from the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2013) which was co-organized by the Reykjavik University (RU) and sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC). SIMULTECH 2013 was held in cooperation with the ACM SIGSIM - Special Interest Group (SIG) on SImulation and Modeling (SIM), Movimento Italiano Modellazione e Simulazione (MIMOS) and AIS Special Interest Group on Modeling and Simulation (AIS SIGMAS) and technically co-sponsored by the Society for Modeling & Simulation International (SCS), Liophant Simulation, Simulation Team and International Federation for Information Processing (IFIP). This proceedings brings together researchers, engineers, applied mathematicians and practitioners working in the advances and applications in the field of system simulation.

  17. An Optical Design for a 3rd Generation Dispersed Fourier Transform Spectrometer

    Science.gov (United States)

    Kazemzadeh, Farnoud; Hajian, A. R.; Behr, B. B.

    2010-05-01

    We present design metrics and numerical simulations aimed at optimizing the performance of the current 3rd generation and future generations of the dispersed Fourier Transform Spectrometer (dFTS). The original dFTS and modified versions of the spectrometer package have demonstrated their value over the past decade in areas ranging from remote sensing in astrophysics to medical diagnostic technologies. The first and second generation dFTS instruments have measured multiple SB1 and SB2 stellar orbits, and have enabled the determination of stellar masses with extreme precision. Based on our analysis of dFTS3, we present our expectations for the capabilities and radial velocity performance of this soon-to-be-built spectrometer.

  18. Virtual Visit to the ATLAS Control Room by 1st and 3rd Lyceums in Chios

    CERN Multimedia

    2013-01-01

    High school students from the 1st and 3rd Lyceums of Chios, Greece, will be visiting the control room of ATLAS to discuss the latest results on the Higgs search, LHC’s first long shutdown and what the future holds for the ATLAS experiment. This visit takes place in the context of a Masterclass where students will learn how to analyse real events from the LHC with the use of the HYPATIA online applet based on educational scenarios from the Discover the COSMOS portal. This full-day activity is organized by the University of Athens, the University of the Aegean, Ellinogermaniki Agogi and the Chios Physical Society in the framework of the Open Discovery Space EU project.

  19. World Health Organization classification of tumors of hematopoietic and lymphoid tissues, 4th edition, 2008: major changes from the 3rd edition, 2001

    OpenAIRE

    Zerbini, Maria Claudia Nogueira; Soares, Fernando Augusto; Velloso, Elvira Deolinda Rodrigues Pereira; Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP; Paes, Roberto Pinto

    2011-01-01

    A Classificação da Organização Mundial da Saúde (OMS) para os tumores do tecido hematopoético e linfoide (4ª edição, 2008)¹ representa uma atualização da 3ª edição, 2001². Apresentamos a seguir um resumo dessas alterações nos grupos das doenças mieloproliferativas, mileodisplásicas, leucemias mieloides agudas, neoplasias de células precursoras B e T, e neoplasias de células B, T e NK maduras. O entendimento das alterações genético-moleculares e os resultados alcançados com propostas terapêuti...

  20. [Diabetic Kidney Disease 3rd stage - laboratory markers of mineral bone disorder].

    Science.gov (United States)

    Klimentová, Adriana; Ságová, Ivana; Prídavková, Dana; Kantárová, Daniela; Makovický, Pavol; Sadloňová, Jurina; Mokáň, Marián

    Diabetes mellitus is the most common cause of end stage kidney disease in the developed countries. Chronic kidney disease-mineral and bone disorder (CKD-MBD) develops with deteriorating of the renal functions. Diabetic patients on hemodialysis are characterized by low bone turnover, higher prevalence of severe and progressive vascular calcification with increased cardiovascular morbidity and mortality. The main factor which causes vascular calcification in patients with diabetic kidney disease (DKD) is poor glycemic control. The recent trial findings describe an inverse correlation between intact parathyroid hormone (iPTH) serum levels and glycemic control in a group of diabetic patients on hemodialysis. The objective of the proposed project is to access the difference of the laboratory markers MBD in the group of patients with 3rd stage DKD depending on glycemic control. We focused on the relationship between the glycemic compensation of diabetes (HbA1c) and iPTH serum level. Ninety one patients with 3rd stage DKD were investigated. There were 46 women (50.5 %) and 45 men (49.5 %), average age of patients was 71.2 ± 7.0 years, with creatinine level 128 ± 30 μmol/l and estimated glomerular filtration (eGF, MDRD) 0.82 ± 0.16 ml/s. There were 60 patients with better glycemic control of diabetes (HbA1c 7 %). MBD markers were compared in both groups. Patients were further stratified into subgroups based on the serum level of iPTH (iPTH 35 pg/ml) and MBD markers compared. Statistical analysis was performed using and Mann-Whitney test. We have found the statistical significance in the serum phosphate and proteinuria levels in between groups with HbA1c 7 %. Diabetics with better glycemic control had significant reduction in serum phosphate level (1.14 ± 0.20 vs 1.23 ± 0.18 mmol/l, p = 0.038) and in 24 hrs proteinuria level (0.56 ± 1.35 vs 1.30 ± 1.61 g/day, p = 0.007). In the group of presumed low bone turnover (iPTH disorder in earlier stages of DKD. diabetes

  1. 3rd International Conference of Open and Distance Learning (ICODL 2005 held in Patra, Greece

    Directory of Open Access Journals (Sweden)

    3rd International Conference of Open and Distance Learning (ICODL 2005 held in Patra, Greece

    2006-01-01

    Full Text Available NOTE FOR TOJDE EDITOR 3rd International Conference of Open and Distance Learning (ICODL 2005 held in Patra, Greece Dear Friends and Tojde Readers, First of all I would like to thank very much those who participated in the 3rd International Conference of Open and Distance Learning (ICODL 2005 in Patra, Greece. Those who couldn't come, I hope to meet them some time in the future. I personally want to give my thanks to all who sent their papers for the Conference and trusted us for the organization of the Conference and our involvement in Open and Distance Learning. In total, the 3 days of the Conference there were 620 people (registered who attended the presentations and panels and about 70 people. The proceedings of the Conference are in two volumes; Volume A (pages 686 and Volume B (pages 592. All those presentations (names and titles which are in the final programme (see http://artemis.eap.gr/icodl2005 are included in the proceedings. I must inform you that the majority of the papers are in Greek. I haven't counted the English language papers, but I presume that they must be around 40. The success of the ICODL 2005 is already leading us to the preparation of the next conference which - I believe - will take place in Athens in the year 2007. I will keep you informed for our plans. At the same time the Hellenic Network of Open and Distance Education (H-NODE in cooperation with the 'Propobos Publishing Company' has published the second issue of the Journal 'Open Education'. If you want information about the Journal you can contact 'Propobos Publishing Company': E-mail propobos@propobos.gr. The H-NODE in cooperation with the Department of Education - University of Crete is also organizing a "Summer School" in the town of Rethymnon (Crete in July 2006 (16-23. The "Summer School" will take place in the campus which is by the sea and will be only in Greek. Last year we had organized a similar "Summer School" in the island of Kefalonia, in the west

  2. 3rd International Arab Forensic Sciences & Forensic Medicine Conference, ASFSFM 2017: Conference Report

    Directory of Open Access Journals (Sweden)

    Abdulsallam A. Bakdash

    2017-12-01

    Full Text Available The Arab Society for Forensic Sciences and Forensic Medicine (ASFSFM at Naif Arab University for Security Sciences seeks to present the latest developments in all fields of forensic sciences through holding specialized scientific events and academic activities. This is also achieved through its periodic scientific peer-reviewed journal, the Arab Journal of Forensic Sciences and Forensic Medicine. It also seeks to promote scientific research in all fields of forensic science and forensic medicine, and seeks actively to contribute in holding scientific meetings in accordance with advanced scientific standards, including the 3rd International Arab Forensic Sciences & Forensic Medicine Conference. This important event was attended by scientists and experts from various fields of criminal and forensic sciences from both Arab and non-Arab countries. This conference was a significant scientific accomplishment that contributed to the advancement of forensic sciences and forensic medicine in the Arab world. The conference aimed, in accordance with the vision of Naif Arab University for Security Sciences, to enhance peace, security and justice in Arab societies.  Naif Arab University for Security Sciences, represented by the Arab Society for Forensic Sciences and Forensic Medicine, held the 3rd International Arab Forensic Sciences & Forensic Medicine Conference on the University's campus during the period from 21st to 23rd November 2017. The event included the participation of more than 720 experts in forensic sciences and forensic medicine from 33 countries all over the world. Experts discussed and presented the latest developments in their fields. The conference provided a creative environment for students from both local and international universities to benefit from experts and specialists, and to access the most recent research.  On behalf of His Excellency the president of Naif Arab University for Security Sciences, and the Arab Society for

  3. On the Generalisation of Kepler's 3rd Law for the Vacuum Field of the Point-Mass

    Directory of Open Access Journals (Sweden)

    Crothers S. J.

    2005-07-01

    Full Text Available I derive herein a general form of Kepler’s 3rd Law for the general solution to Einstein’s vacuum field. I also obtain stable orbits for photons in all the configurations of the point-mass. Contrary to the accepted theory, Kepler’s 3rd Law is modified by General Relativity and leads to a finite angular velocity as the proper radius of the orbit goes down to zero, without the formation of a black hole. Finally, I generalise the expression for the potential function of the general solution for the point-mass in the weak field.

  4. On the Generalisation of Kepler's 3rd Law for the Vacuum Field of the Point-Mass

    OpenAIRE

    Crothers S. J.

    2005-01-01

    I derive herein a general form of Kepler’s 3rd Law for the general solution to Einstein’s vacuum field. I also obtain stable orbits for photons in all the configurations of the point-mass. Contrary to the accepted theory, Kepler’s 3rd Law is modified by General Relativity and leads to a finite angular velocity as the proper radius of the orbit goes down to zero, without the formation of a black hole. Finally, I generalise the expression for the potential function of the general solution for t...

  5. [Methodology for an appreciative, dynamic and collaborative process: 3rd Canary Islands (Spain) Health Plan].

    Science.gov (United States)

    O'Shanahan Juan, José Joaquín; Hernández Rodríguez, Miguel Ángel; Del Otero Sanz, Laura; Henríquez Suárez, José Andrés; Mahtani Chugani, Vinita

    The need for new approaches to strategic planning by incorporating the perspectives of professionals and inhabitants has led to a new model for the 3rd Canary Islands (Spain) Health Plan (IIIPSC). A dual-phase participatory process using qualitative techniques is proposed: 1) local phase: a quantitative and qualitative study based on training and a research-action-participation initiative; and 2) insular phase: health conferences with face-to-face discussion of results in each health area (island) and proposals for action. The process prioritises problems and establishes a specific action plan for each island through initiatives that are considered to be viable, grouped by themes and weighted according to the potential impact on priority problems. This process of interaction may help to guide planning model changes and health policy decision-making, and was included in the IIIPSC Project for its parliamentary procedure. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. A critical experimental test of synchrotron radiation theory with 3rd generation light source

    Energy Technology Data Exchange (ETDEWEB)

    Geloni, Gianluca [European XFEL GmbH, Hamburg (Germany); Kocharyan, Vitali; Saldin, Evgeni [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2016-05-15

    A recent ''beam splitting'' experiment at LCLS apparently demonstrated that after a microbunched electron beam is kicked on a large angle compared to the divergence of the FEL radiation, the microbunching wave front is readjusted along the new direction of motion of the kicked beam. Therefore, coherent radiation from an undulator placed after the kicker is emitted along the kicked direction without suppression. This strong emission of coherent undulator radiation in the kicked direction cannot be explained in the framework of conventional synchrotron radiation theory. In a previous paper we explained this puzzle. We demonstrated that, in accelerator physics, the coupling of fields and particles is based, on the one hand, on the use of results from particle dynamics treated according to the absolute time convention and, on the other hand, on the use of Maxwell equations treated according to the standard (Einstein) synchronization convention. Here lies the misconception which led to the strong qualitative disagreement between theory and experiment. After the ''beam splitting'' experiment at LCLS, it became clear that the conventional theory of synchrotron radiation cannot ensure the correct description of coherent and spontaneous emission from a kicked electron beam, nor the emission from a beam with finite angular divergence, in an undulator or a bending magnet. However, this result requires further experimental confirmation. In this publication we propose an uncomplicated and inexpensive experiment to test synchrotron radiation theory at 3rd generation light sources.

  7. China Satellite Navigation Conference (CSNC) 2012 Proceedings : The 3rd China Satellite Navigation Conference

    CERN Document Server

    Liu, Jingnan; Yang, Yuanxi; Fan, Shiwei

    2012-01-01

    Proceedings of the 3rd China Satellite Navigation Conference (CSNC2012) presents selected research papers from CSNC2012, held on 15-19 May in Guanzhou, China. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou system especially. They are divided into 9 topics to match the corresponding sessions in CSNC2012, which broadly covered key topics in GNSS. Readers can learn about the BeiDou system and keep abreast of the latest advances in GNSS techniques and applications. SUN Jiadong is the Chief Designer of the Compass/BeiDou system, and the Academician of Chinese Academy of Sciences; LIU Jingnan is a professor at Wuhan University, and the Academician of Chinese Academy of Engineering; YANG Yuanxi is a professor at China National Administration of GNSS and Applications, and the Academician of Chinese Academy of Sciences; FAN Shiwei öis a researcher on satellite navigation.

  8. SESAME-A 3rd Generation Synchrotron Light Source for the Middle East

    Science.gov (United States)

    Winick, Herman

    2010-02-01

    Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research center in construction in Jordan. It will enable world class research by scientists from the region, reversing the brain drain. It will also build bridges between diverse societies, contributing to a culture of peace through international cooperation in science. The centerpiece is a synchrotron light source originating from BESSY I, a gift by Germany. The upgraded machine, a 2.5 GeV 3rd Generation Light Source (133m circumference, 26nm-rad emittance and 12 places for insertion devices), will provide light from infra-red to hard X-rays, offering excellent opportunities to train local scientists and attract those working abroad to return. The SESAME Council meets twice each year and presently has nine Members (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority, Turkey). Members have responsibility for the project and provide the annual operations budget (1.5M US dollars in 2009, expected to rise to about 5M when operation starts in 2012-13). Jordan provided the site, building, and infrastructure. A staff of 20 is installing the 0.8 GeV BESSY I injection system. The facility will have the capacity to serve 30 or more experiments operating simultaneously. See www.sesame.org.jo )

  9. Book Review: Guide to computer forensics and investigations (3rd ed.

    Directory of Open Access Journals (Sweden)

    Keyu Jiang

    2008-09-01

    Full Text Available Nelson, B., Phillips, A., Enfinger, F., & Steuart, C. (2008. Guide to computer forensics and investigations (3rd ed.. New Jersey: Pearson Education, Inc. 693 pages, ISBN: 1-4180-6733-4 (paper.Reviewed by Keyu Jiang (kjiang@fhsu.edu and Ruifeng Xuan (r_xuan@scatcat.fhsu.edu, Department of Information Networking and Telecommunications, Fort Hays State University, Hays, KS 67601Nelson, Phillips, Enfinger, and Steuart’s book is about the science of computer forensics and its implications in crime investigations. This book is not intended to provide comprehensive training in computer forensics, but introduce the science the science of computer forensics and its implications in crime investigations.  It focused on establishing a solid foundation for those who are new to this field.  Nelson, Philips, Enfiger, and Steuart are experienced experts in different areas of computer forensics.  Different expertise makes this book could benefit many groups of people at different educational level and industrial background.(see PDF for full review

  10. Visual, Critical, and Scientific Thinking Dispositions in a 3rd Grade Science Classroom

    Science.gov (United States)

    Foss, Stacy

    Many American students leave school without the required 21st century critical thinking skills. This qualitative case study, based on the theoretical concepts of Facione, Arheim, and Vygotsky, explored the development of thinking dispositions through the arts in science on the development of scientific thinking skills when used as a conceptual thinking routine in a rural 3rd grade classroom. Research questions examined the disposition to think critically through the arts in science and focused on the perceptions and experiences of 25 students with the Visual Thinking Strategy (VTS) process. Data were collected from classroom observations (n = 10), student interviews (n = 25), teacher interviews ( n = 1), a focus group discussion (n = 3), and artifacts of student work (n = 25); these data included perceptions of VTS, school culture, and classroom characteristics. An inductive analysis of qualitative data resulted in several emergent themes regarding disposition development and students generating questions while increasing affective motivation. The most prevalent dispositions were open-mindedness, the truth-seeking disposition, the analytical disposition, and the systematicity disposition. The findings about the teachers indicated that VTS questions in science supported "gradual release of responsibility", the internalization of process skills and vocabulary, and argumentation. This case study offers descriptive research that links visual arts inquiry and the development of critical thinking dispositions in science at the elementary level. A science curriculum could be developed, that emphasizes the development of thinking dispositions through the arts in science, which in turn, could impact the professional development of teachers and learning outcomes for students.

  11. High Art and High Stakes: The 3rd Duke of Dorset’s Gamble on Reynolds

    Directory of Open Access Journals (Sweden)

    John Chu

    2016-04-01

    Full Text Available This article explores the art-collecting practices of John Frederick Sackville, 3rd Duke of Dorset (1745–1799, focusing on his remarkable investment in the experimental paintings of Sir Joshua Reynolds (1723–1792. In the 1770s and 80s, Sackville sunk significant funds into works by Reynolds that were of mixed critical standing, of unpredictable future value, and notoriously susceptible to rapid physical deterioration. What motivated such risky, idiosyncratic purchases? This article argues that Sackville’s patronage can usefully be characterized as a form of high-stakes gamble with the potential to advance his social, cultural, and political circumstances and agendas. It is argued that such a “Reynoldsian lottery” was as much about interior competition in the uppermost reaches of eighteenth-century society as it was about an outward-looking desire to be distinguished from the ranks below. As well as shedding light on an important instance of British art patronage therefore, the article also seeks to expose the tactical advantage of devil-may-care forms of luxury consumption for those born to rank, fortune, and influence in this period.

  12. Recent developments at 3rd generation storage ring light sources (2/4)

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Over the last decade, many 3rd generation storage ring light sources have been built and put into operation. Progressively, significant improvements have been brought to the machine performances and experiences developed at the first facilities have benefited to the most recently built ones. Most of the recent facilities are now featuring small emittances, high current together with high position stability. The small sizes of the electron beam at the source points impose achieving position stabilities in the sub micron range. The technology to build the insertion devices that produce the photon beams has reached a very mature state and enables 3 GeV medium energy /medium size machines to produce high brilliance beams up to the hard X-Ray range (10 - 30 keV). The designing of the optical set-up of a beamline includes now the choice of the best suited undulator. All these facilities are operated as “photon factories” and deliver their beams to many beamlines over several thousands hours per year. Some re...

  13. Recent developments at 3rd generation storage ring light sources (1/4)

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Over the last decade, many 3rd generation storage ring light sources have been built and put into operation. Progressively, significant improvements have been brought to the machine performances and experiences developed at the first facilities have benefited to the most recently built ones. Most of the recent facilities are now featuring small emittances, high current together with high position stability. The small sizes of the electron beam at the source points impose achieving position stabilities in the sub micron range. The technology to build the insertion devices that produce the photon beams has reached a very mature state and enables 3 GeV medium energy /medium size machines to produce high brilliance beams up to the hard X-Ray range (10 - 30 keV). The designing of the optical set-up of a beamline includes now the choice of the best suited undulator. All these facilities are operated as “photon factories” and deliver their beams to many beamlines over several thousands hours per year. Some re...

  14. Recent developments at 3rd generation storage ring light sources (4/4)

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Over the last decade, many 3rd generation storage ring light sources have been built and put into operation. Progressively, significant improvements have been brought to the machine performances and experiences developed at the first facilities have benefited to the most recently built ones. Most of the recent facilities are now featuring small emittances, high current together with high position stability. The small sizes of the electron beam at the source points impose achieving position stabilities in the sub micron range. The technology to build the insertion devices that produce the photon beams has reached a very mature state and enables 3 GeV medium energy /medium size machines to produce high brilliance beams up to the hard X-Ray range (10 - 30 keV). The designing of the optical set-up of a beamline includes now the choice of the best suited undulator. All these facilities are operated as “photon factories” and deliver their beams to many beamlines over several thousands hours per year. Some re...

  15. Recent developments at 3rd generation storage ring light sources (3/4)

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Over the last decade, many 3rd generation storage ring light sources have been built and put into operation. Progressively, significant improvements have been brought to the machine performances and experiences developed at the first facilities have benefited to the most recently built ones. Most of the recent facilities are now featuring small emittances, high current together with high position stability. The small sizes of the electron beam at the source points impose achieving position stabilities in the sub micron range. The technology to build the insertion devices that produce the photon beams has reached a very mature state and enables 3 GeV medium energy /medium size machines to produce high brilliance beams up to the hard X-Ray range (10 - 30 keV). The designing of the optical set-up of a beamline includes now the choice of the best suited undulator. All these facilities are operated as “photon factories” and deliver their beams to many beamlines over several thousands hours per year. Some re...

  16. Resurgence of duckweed research and applications: report from the 3rd International Duckweed Conference.

    Science.gov (United States)

    Appenroth, Klaus-J; Sree, K Sowjanya; Fakhoorian, Tamra; Lam, Eric

    2015-12-01

    Duckweed, flowering plants in the Lemnaceae family, comprises the smallest angiosperms in the plant kingdom. They have some of the fastest biomass accumulation rates reported to date for plants and have the demonstrated ability to thrive on wastewater rich in dissolved organic compounds and thus could help to remediated polluted water resources and prevents eutrophication. With a high quality genome sequence now available and increased commercial interest worldwide to develop duckweed biomass for renewables such as protein and fuel, the 3rd International Duckweed Conference convened at Kyoto, Japan, in July of 2015, to update the community of duckweed researchers and developers on the progress in the field. In addition to sharing results and ideas, the conference also provided ample opportunities for new-comers as well as established workers in the field to network and create new aliances. We hope this meeting summary will also help to disseminate the key advances and observations that have been presented in this conference to the broader plant biology community in order to encourage increased cross-fertilization of ideas and technologies.

  17. 3rd International Conference on Opto-Electronics and Applied Optics

    CERN Document Server

    Chakrabarti, Satyajit; Reehal, Haricharan; Lakshminarayanan, Vasudevan

    2017-01-01

    The Proceedings of 3rd International Conference on Opto-Electronics and Applied Optics, OPTRONIX 2016 is an effort to promote and present the research works by scientists and researchers including students in India and abroad in the area of Green Photonics and other related areas as well as to raise awareness about the recent trends of research and development in the area of the related fields. The book has been organized in such a way that it will be easier for the readers to go through and find out the topic of their interests. The first part includes the Keynote addresses by Rajesh Gupta, Department of Energy Science and Engineering, Indian Institute of Technology, Bombay; P.T. Ajith Kumar, President and Leading Scientist Light Logics Holography and Optics, Crescent Hill, Trivandrum, Kerala; and K.K. Ghosh, Institute of Engineering & Management, Kolkata, India.  The second part focuses on the Plenary and Invited Talks given by eminent scientists namely, Vasudevan Lakshminarayanan, University of Wate...

  18. Medicinal plants profile used by the 3rd District population of Maceió-AL

    Directory of Open Access Journals (Sweden)

    S. A. S. Griz

    2017-05-01

    Full Text Available Abstract Herein the use of medicinal plants by the population of the 3rd Sanitary District of Maceió-AL city is reported. Transversal description was conducted from February 2013 to January 2014, with a sample of 116 individuals of both Gender Genders aged over 18 years. The ethnobotanical information interviews ethnobotanical information were obtained through semi - structured questionnaire featuring the use of medicinal plants and social and economical data. Descriptive statistics was applied for quantitative variables as mean and standard deviation and proportions for qualitative variables in the frequency table format. The results showed that 85.34% of the interviewees used plants for medicinal purposes. As the majority of these were (73.28% females in the age group between 30-60 years of old. Among a total of 45 identified plant species, the highest use frequency were for Boldus Peumus (bilberry, Melissa officinalis (lemon balm, and Mentha piperita (mint. The most widely used plant foliage part was (53.53% prepared as an infusion (55.5%. The use of medicinal plants in Maceió cityis widespread, highlighting the importance of ethnobotanical knowledge for the study of medicinal plants.

  19. PREFACE: 3rd International Conference on Manufacturing, Optimization, Industrial and Material Engineering (MOIME 2015)

    Science.gov (United States)

    Lumban Gaol, Ford; Webb, Jeff; Ding, Jun

    2015-05-01

    The 3rd International Conference on Manufacturing, Optimization, Industrial and Material Engineering (MOIME 2015) was held at the Sheraton Kuta, Bali, Indonesia, from 28 - 29 March 2015. The MOIME 2015 conference is aimed to bring together researchers, engineers and scientists in the domain of interest from around the world. MOIME 2015 is placed on promoting interaction between the theoretical, experimental, and applied communities, so that a high level exchange is achieved in new and emerging areas within Material Engineering, Industrial Engineering and all areas that relate to Optimization. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program, as well as the invited and plenary speakers. This year, we received 99 papers and after rigorous review, 24 papers were accepted. The participants come from eight countries. There were four parallel sessions and two invited speakers. It is an honour to present this volume of IOP Conference Series: Materials Science and Engineering (MSE) and we deeply thank the authors for their enthusiastic and high-grade contributions. Finally, we would like to thank the conference chairmen, the members of the steering committee, the organizing committee, the organizing secretariat and the financial support from the conference sponsors that allowed the success of MOIME 2015. The Editors of the MOIME 2015 Proceedings Dr. Ford Lumban Gaol Jeff Webb, Ph.D Prof. Jun DING, Ph.D

  20. The 3^rd International Conference on Women in Physics: Global Perspectives, Common Concerns, Worldwide Views

    Science.gov (United States)

    Zastavker, Yevgeniya V.

    2009-03-01

    The 3^rd International Conference on Women in Physics (ICWIP), held in Seoul, Korea, in October 2008, brought together 300 participants from 57 countries, including a diverse 22-member U.S. Delegation, for a 3-day summit of stimulating discussions, thought-provoking presentations, inspirational posters, and networking. Held under the auspices of the Working Group on Women in Physics of the International Union of Pure and Applied Physics (IUPAP), this meeting built on the successes of the 1^st (Paris, 2002) and 2^nd (Rio de Janeiro, 2005) Conferences and further clarified the importance of diversifying the field of physics worldwide. Although considerable progress has been made since 2002, it was clear that the global scientific workforce is still under-utilizing a large percentage of the available female talent pool. If human society is to benefit to its fullest from various contributions that the field of physics can offer in addressing global issues of economic crisis, energy, environment, water, health, poverty, and hunger, women of all races and nationalities need to become fully included and engaged in the national and international physical community. To address these and many other issues, the ICWIP unanimously approved a five-part resolution to IUPAP recommending actions to promote the recruitment, retention, and advancement of women in physics and related fields.

  1. The Power of PreK-3rd: How a Small Foundation Helped Push Washington State to the Forefront of the PreK-3rd Movement. FCD Case Study

    Science.gov (United States)

    Nyhan, Paul

    2011-01-01

    The New School Foundation was not born from a commission, legislative mandate, research project, think tank, or even the mind of a leading education scholar. One of Washington state's pioneering PreK-3rd initiatives began as the brainchild of a wealthy Seattle businessman, Stuart Sloan, 20 years ago. The New School Foundation and its ideas were…

  2. 3rd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of pancreatic cancer

    NARCIS (Netherlands)

    Lutz, M.P. (Manfred P.); J. Zalcberg (John); M. Ducreux (Michel); G. Aust (Gabriela); M.J. Bruno (Marco); M.W. Buchler (M.); Delpero, J.-R. (Jean-Robert); Gloor, B. (Beat); R. Glynne-Jones; Hartwig, W. (Werner); Huguet, F. (Florence); P. Laurent-Puig (Pierre); F. Lordick (Florian); P. Maisonneuve (Patrick); J. Mayerle (Julia); Martignoni, M. (Marc); J.P. Neoptolemos (John); Rhim, A.D. (Andrew D.); Schmied, B.M. (Bruno M.); T. Seufferlein (Thomas); Werner, J. (Jens); van Laethem, J.-L. (Jean-Luc); F. Otto (Florian)

    2017-01-01

    textabstractThe primary treatment of pancreatic cancer was the topic of the 3rd St. Gallen Conference 2016. A multidisciplinary panel reviewed the current evidence and discussed controversial issues in a moderated consensus session. Here we report on the key expert recommendations. It was generally

  3. Visual Arts Teaching in Kindergarten through 3rd-Grade Classrooms in the UAE: Teacher Profiles, Perceptions, and Practices

    Science.gov (United States)

    Buldu, Mehmet; Shaban, Mohamed S.

    2010-01-01

    This study portrayed a picture of kindergarten through 3rd-grade teachers who teach visual arts, their perceptions of the value of visual arts, their visual arts teaching practices, visual arts experiences provided to young learners in school, and major factors and/or influences that affect their teaching of visual arts. The sample for this study…

  4. The 3rd Schizophrenia International Research Society Conference, 14-18 April 2012, Florence, Italy: Summaries of oral sessions

    NARCIS (Netherlands)

    Abbs, Brandon; Achalia, Rashmin M.; Adelufosi, Adegoke O.; Aktener, Ahmet Yiğit; Beveridge, Natalie J.; Bhakta, Savita G.; Blackman, Rachael K.; Bora, Emre; Byun, M. S.; Cabanis, Maurice; Carrion, Ricardo; Castellani, Christina A.; Chow, Tze Jen; Dmitrzak-Weglarz, M.; Gayer-Anderson, Charlotte; Gomes, Felipe V.; Haut, Kristen; Hori, Hiroaki; Kantrowitz, Joshua T.; Kishimoto, Taishiro; Lee, Frankie H. F.; Lin, Ashleigh; Palaniyappan, Lena; Quan, Meina; Rubio, Maria D.; Ruiz de Azúa, Sonia; Sahoo, Saddichha; Strauss, Gregory P.; Szczepankiewicz, Aleksandra; Thompson, Andrew D.; Trotta, Antonella; Tully, Laura M.; Uchida, Hiroyuki; Velthorst, Eva; Young, Jared W.; O'Shea, Anne; DeLisi, Lynn E.

    2012-01-01

    The 3rd Schizophrenia International Research Society Conference was held in Florence, Italy, April 14-18, 2012 and this year had as its emphasis, "The Globalization of Research". Student travel awardees served as rapporteurs for each oral session and focused their summaries on the most significant

  5. Constancy and Variability: Dialogic Literacy Events as Sites for Improvisation in Two 3rd-Grade Classrooms

    Science.gov (United States)

    Jordan, Michelle E.; Santori, Diane

    2015-01-01

    This multisite study investigates dialogic literacy events that revolved around narrative and informational texts in two 3rd-grade classrooms. The authors offer a metaphor of musical improvisation to contemplate dialogic literacy events as part of the repertoire of teaching and learning experiences. In literacy learning, where there is much…

  6. PREFACE: 3rd International Youth Conference "Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology" (Nanobiotech 2015)

    Science.gov (United States)

    Refsnes, Magne, Prof; Gusev, Alexander, Dr; Godymchuk, Anna, Dr; Bogdan, Anna

    2015-11-01

    The 3rd International Youth Conference "Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology" (Nanobiotech2015) was held on 21-22 May 2015 in Tambov, Russia, and was jointly organized by Tambov Derzhavin State University (Russia), the Norwegian Institute of Public Health (Norway), the National University of Science and Technology MISiS (Russia), Tomsk Polytechnic University (Russia) and Tomsk State University. The conference gathered experienced and young researchers, post-docs and students, working in the fieldof nanotechnologies, nanomedicine, nano(eco)toxicology and risk assessment of nanomaterials, in order to facilitate the aggregation and sharing of interests and results for better collaboration and visibility of activity. The goal of Nanobiotech2015 was to bring researchers and practitioners together to share the latest knowledge on nanotechnology-specific risks to occupational and environmental health and assessing how to reduce these potential risks. The main objective of the conference is to identify, systematize and solve current scientific problems inthe sphere of nanobiotechnologies, nanomedicine and nanotoxicology, in order to join forces todetermine prospective areas and compose working groups of interested co-workers for carrying out interdisciplinary research projects. The topics of Nanobiotech2015 were: (1) Nanotechnologies in pharmaceutics and medicine; (2) Sources and mechanisms of nanoparticle release into the environment; (3) Ecological and biological effects of nanoparticles; (4) (Eco)toxicology of nanomaterials; (5) Methods for detection of nanoparticles in the environment and in biological objects; and (6) Physico-chemical properties of nanoparticles in the environment. We want to thank the Organizing Committee, the universities and sponsors supporting the conference,and everyone who contributed to the organization of this meeting, for their contribution towards the conference and for their contributions to these

  7. 3rd hand smoking; heterogeneous oxidation of nicotine and secondary aerosol formation in the indoor environment

    Science.gov (United States)

    Petrick, Lauren; Dubowski, Yael

    2010-05-01

    Tobacco smoking is well known as a significant source of primary indoor air pollutants. However, only recently has it been recognized that the impact of Tobacco smoking may continue even after the cigarette has been extinguished (i.e., third hand smoke) due to the effect of indoor surfaces. These surfaces may affect the fate of tobacco smoke in the form of secondary reactions and pollutants, including secondary organic aerosol (SOA) formation. Fourier Transform Infrared spectrometry with Attenuated Total Reflection (FTIR-ATR) in tandem with a Scanning Mobility Particle Sizing (SMPS) system was used to monitor the ozonation of cellulose sorbed nicotine and resulting SOA formation. SOA formation began at onset of ozone introduction ([O3] = 60 ± 5 ppb) with a size distribution of dp ≤ 25 nm, and was determined to be a result of heterogeneous reaction (opposed to homogeneous). SOA yield from reacted surface nicotine was on the order of 10 %. Simultaneous to SOA monitoring, FTIR-ATR spectra showed surface changes in the nicotine film as the reaction progressed, revealing a pseudo first-order surface reaction rate of 0.0026 ± 0.0008 min-1. Identified surface oxidation products included: cotinine, myosmine, methylnicotinamide and nicotyrine. Surface reaction rate was found to be partially inhibited at high relative humidity. Given the toxicity of some of the identified products (e.g., cotinine has shown potential mutagenicity and teratogenicity) and that small particles may contribute to adverse health effects, the present study indicates that exposure to 3rd hand smoke ozonation products may pose additional health risks.

  8. 3rd ACIS International Conference on Applied Computing and Information Technology

    CERN Document Server

    2016-01-01

    This edited book presents scientific results of the 3nd International Conference on Applied Computing and Information Technology (ACIT 2015) which was held on July 12-16, 2015 in Okayama, Japan. The aim of this conference was to bring together researchers and scientists, businessmen and entrepreneurs, teachers, engineers, computer users, and students to discuss the numerous fields of computer science and to share their experiences and exchange new ideas and information in a meaningful way. Research results about all aspects (theory, applications and tools) of computer and information science, and to discuss the practical challenges encountered along the way and the solutions adopted to solve them.

  9. PREFACE: 3rd International Workshop on Statistical Physics and Mathematics for Complex Systems (SPMCS 2012)

    Science.gov (United States)

    Tayurskii, Dmitrii; Abe, Sumiyoshi; Alexandre Wang, Q.

    2012-11-01

    The 3rd International Workshop on Statistical Physics and Mathematics for Complex Systems (SPMCS2012) was held between 25-30 August at Kazan (Volga Region) Federal University, Kazan, Russian Federation. This workshop was jointly organized by Kazan Federal University and Institut Supérieur des Matériaux et Mécaniques Avancées (ISMANS), France. The series of SPMCS workshops was created in 2008 with the aim to be an interdisciplinary incubator for the worldwide exchange of innovative ideas and information about the latest results. The first workshop was held at ISMANS, Le Mans (France) in 2008, and the third at Huazhong Normal University, Wuhan (China) in 2010. At SPMCS2012, we wished to bring together a broad community of researchers from the different branches of the rapidly developing complexity science to discuss the fundamental theoretical challenges (geometry/topology, number theory, statistical physics, dynamical systems, etc) as well as experimental and applied aspects of many practical problems (condensed matter, disordered systems, financial markets, chemistry, biology, geoscience, etc). The program of SPMCS2012 was prepared based on three categories: (i) physical and mathematical studies (quantum mechanics, generalized nonequilibrium thermodynamics, nonlinear dynamics, condensed matter physics, nanoscience); (ii) natural complex systems (physical, geophysical, chemical and biological); (iii) social, economical, political agent systems and man-made complex systems. The conference attracted 64 participants from 10 countries. There were 10 invited lectures, 12 invited talks and 28 regular oral talks in the morning and afternoon sessions. The book of Abstracts is available from the conference website (http://www.ksu.ru/conf/spmcs2012/?id=3). A round table was also held, the topic of which was 'Recent and Anticipated Future Progress in Science of Complexity', discussing a variety of questions and opinions important for the understanding of the concept of

  10. ic-cmtp3: 3rd International Conference on Competitive Materials and Technology Processes

    Science.gov (United States)

    2016-04-01

    Competitiveness is one of the most important factors in our lives and it plays a key role in the efficiency both of organizations and societies. The more scientifically advanced and prepared organizations develop more competitive materials with better physical, chemical, and biological properties, and the leading companies apply more competitive equipment and technological processes. The aims of the 3rd International Conference on Competitive Materials and Technology Processes (ic-cmtp3), and the 1st International Symposium on Innovative Carbons and Carbon Based Materials (is-icbm1) and the 1st International Symposium on Innovative Construction Materials (is-icm1) organized alongside are the following: —Promote new methods and results of scientific research in the fields of material, biological, environmental and technological sciences; —Exchange information between the theoretical and applied sciences as well as technical and technological implementations; —Promote communication and collaboration between the scientists, researchers and engineers of different nations, countries and continents. Among the major fields of interest are advanced and innovative materials with competitive characteristics, including mechanical, physical, chemical, biological, medical and thermal, properties and extreme dynamic strength. Their crystalline, nano - and micro-structures, phase transformations as well as details of their technological processes, tests and measurements are also in the focus of the ic-cmtp3 conference and the is-scbm1 and is-icm1 symposia. Multidisciplinary applications of material science and the technological problems encountered in sectors like ceramics, glasses, thin films, aerospace, automotive and marine industries, electronics, energy, construction materials, medicine, biosciences and environmental sciences are of particular interest. In accordance with the program of the ic-cmtp3 conference and is-icbm1 and is-icm1 symposia we have received more

  11. Building monument materials during the 3rd-4rd millennium (Portugal)

    Science.gov (United States)

    Moita, Patricia; Pedro, Jorge; Boaventura, Rui; Mataloto, Rui; Maximo, Jaime; Almeida, Luís; Nogueira, Pedro

    2014-05-01

    Dolmens are the most conspicuous remains of the populations of the 4th and first half of 3rd millennia BCE. These tombs are impressive not only for their monumentality, but also because of the socioeconomic investment they represent for those Neolithic communities, namely from the Central-South of Portugal, who built them. Although dolmens have been studied for their funerary content and typologies, an interdisciplinary approach toward the geological characterization and sourcing of stones used in these constructions has not received enough attention from researchers. With MEGAGEO project a multidisciplinary group of geologist and archaeologists intends to assess the relationship between the distribution of dolmens in Central-South Portugal, their source materials, and the geological landscape. GIS will map the information gathered and will be used to analyse these relationships. The selection of the areas, with distinctive geologies (limestone vs granite), will allow to verify if human patterns of behaviour regarding the selection of megaliths are similar or different regionally. Geologically the first target area (Freixo, Alentejo) is dominated by a small intrusion of gabbro mingled/mixed within a granodioritic intrusion both related with variscan orogeny. Granodiorite exhibit several enclaves of igneous and metamorphic nature attesting the interaction between both igneous rocks as well with enclosing gneisses. Despite Alentejo region have a reduced number of outcrops the granodiorite provides rounded to tabular metric blocks. The gabbro is very coarse grained, sometimes with a cumulate texture, and their fracturing and weathering provide very fresh tabular blocks. The five studied dolmens (Quinta do Freixo #1 to #5) are implanted in a large granodioritic intrusion, around the gabbroic rocks, within an area of approximately 9km2. The medium grained granodiorite is ubiquity in all the dolmens slabs and occasionally it can be observed features of mixing and

  12. EPA Method 3031 (SW-846): Acid Digestion of Oils for Metals Analysis by Atomic Absorption or ICP Spectrometry

    Science.gov (United States)

    Procedures are described for analysis of water samples and may be adapted for assessment of solid, particulate and liquid samples. The method uses real-time PCR assay for detecting Toxoplasma gondii DNA using gene-specific primers and probe.

  13. 3rd International Workshop on Advances in Simulation-Driven Optimization and Modeling

    CERN Document Server

    Leifsson, Leifur; Yang, Xin-She

    2016-01-01

    This edited volume is devoted to the now-ubiquitous use of computational models across most disciplines of engineering and science, led by a trio of world-renowned researchers in the field. Focused on recent advances of modeling and optimization techniques aimed at handling computationally-expensive engineering problems involving simulation models, this book will be an invaluable resource for specialists (engineers, researchers, graduate students) working in areas as diverse as electrical engineering, mechanical and structural engineering, civil engineering, industrial engineering, hydrodynamics, aerospace engineering, microwave and antenna engineering, ocean science and climate modeling, and the automotive industry, where design processes are heavily based on CPU-heavy computer simulations. Various techniques, such as knowledge-based optimization, adjoint sensitivity techniques, and fast replacement models (to name just a few) are explored in-depth along with an array of the latest techniques to optimize the...

  14. 3rd International Conference on Condition Monitoring of Machinery in Non-Stationary Operations

    CERN Document Server

    Rubini, Riccardo; D'Elia, Gianluca; Cocconcelli, Marco; Chaari, Fakher; Zimroz, Radoslaw; Bartelmus, Walter; Haddar, Mohamed

    2014-01-01

    This book presents the processings of the third edition of the Condition Monitoring of Machinery in Non-Stationary Operations (CMMNO13) which was held in Ferrara, Italy. This yearly event merges an international community of researchers who met – in 2011 in Wroclaw (Poland) and in 2012 in Hammamet (Tunisia) – to discuss issues of diagnostics of rotating machines operating in complex motion and/or load conditions. The growing interest of the industrial world on the topics covered by the CMMNO13 involves the fields of packaging, automotive, agricultural, mining, processing and wind machines in addition to that of the systems for data acquisition.The participation of speakers and visitors from industry makes the event an opportunity for immediate assessment of the potential applications of advanced methodologies for the signal analysis. Signals acquired from machines often contain contributions from several different components as well as noise. Therefore, the major challenge of condition monitoring is to po...

  15. Plant chromatin warms up in Madrid: meeting summary of the 3rd European Workshop on Plant Chromatin 2013, Madrid, Spain.

    Science.gov (United States)

    Jarillo, José A; Gaudin, Valérie; Hennig, Lars; Köhler, Claudia; Piñeiro, Manuel

    2014-04-01

    The 3rd European Workshop on Plant Chromatin (EWPC) was held on August 2013 in Madrid, Spain. A number of different topics on plant chromatin were presented during the meeting, including new factors mediating Polycomb Group protein function in plants, chromatin-mediated reprogramming in plant developmental transitions, the role of histone variants, and newly identified chromatin remodeling factors. The function of interactions between chromatin and transcription factors in the modulation of gene expression, the role of chromatin dynamics in the control of nuclear processes and the influence of environmental factors on chromatin organization were also reported. In this report, we highlight some of the new insights emerging in this growing area of research, presented at the 3rd EWPC.

  16. Addressing learning difficulties in Newtons 1st and 3rd Laws through problem based inquiry using Easy Java Simulation

    OpenAIRE

    Goh, Khoon Song Aloysius; Wee, Loo Kang; Yip, Kim Wah; Toh, Ping Yong Jeffrey; Lye, Sze Yee

    2013-01-01

    We develop an Easy Java Simulation (EJS) model for students to visualize Newtons 1st and 3rd laws, using frictionless constant motion equation and a spring collision equation during impact. Using Physics by Inquiry instructional (PbI) strategy, the simulation and its problem based inquiry worksheet aim to enhance learning of these two Newtonian concepts. We report results from Experimental (N=62 students) and Control (N=67) Groups in 11 multiple choice questions pre and post tests, conducted ...

  17. A 3rd Order Low Power SI Sigma-Delta A/D Converter for Voice-Band Applications

    DEFF Research Database (Denmark)

    Jørgensen, Ivan Herald Holger; Bogason, Gudmundur

    1997-01-01

    This paper presents a 3rd order switched current-ΣΔ-modulator. The ΣΔ-modulator operates at a sampling rate of fs=600 kHz and the signal band is fb=5.5 kHz, i.e., an oversampling factor of R=54.5 is used. Multiple input signals are used to reduce the internal signal swings which results in reduce...

  18. PREFACE: 3rd International Workshop on Materials Analysis and Processing in Magnetic Fields (MAP3)

    Science.gov (United States)

    Sakka, Yoshio; Hirota, Noriyuki; Horii, Shigeru; Ando, Tsutomu

    2009-07-01

    The 3rd International Workshop on Materials Analysis and Processing in Materials Fields (MAP3) was held on 14-16 May 2008 at the University of Tokyo, Japan. The first was held in March 2004 at the National High Magnetic Field Laboratory in Tallahassee, USA. Two years later the second took place in Grenoble, France. MAP3 was held at The University of Tokyo International Symposium, and jointly with MANA Workshop on Materials Processing by External Stimulation, and JSPS CORE Program of Construction of the World Center on Electromagnetic Processing of Materials. At the end of MAP3 it was decided that the next MAP4 will be held in Atlanta, USA in 2010. Processing in magnetic fields is a rapidly expanding research area with a wide range of promising applications in materials science. MAP3 focused on the magnetic field interactions involved in the study and processing of materials in all disciplines ranging from physics to chemistry and biology: Magnetic field effects on chemical, physical, and biological phenomena Magnetic field effects on electrochemical phenomena Magnetic field effects on thermodynamic phenomena Magnetic field effects on hydrodynamic phenomena Magnetic field effects on crystal growth Magnetic processing of materials Diamagnetic levitation Magneto-Archimedes effect Spin chemistry Application of magnetic fields to analytical chemistry Magnetic orientation Control of structure by magnetic fields Magnetic separation and purification Magnetic field-induced phase transitions Materials properties in high magnetic fields Development of NMR and MRI Medical application of magnetic fields Novel magnetic phenomena Physical property measurement by Magnetic fields High magnetic field generation> MAP3 consisted of 84 presentations including 16 invited talks. This volume of Journal of Physics: Conference Series contains the proceeding of MAP3 with 34 papers that provide a scientific record of the topics covered by the conference with the special topics (13 papers) in

  19. CELEBRATION OF DECEMBER 3RD, INTERNATIONAL DAY OF PERSONS WITH DISABILITIES

    Directory of Open Access Journals (Sweden)

    Maja FILIPOVSKA

    2017-03-01

    Full Text Available On December 2nd 2016 in the main amphitheater at the Faculty of Philosophy in Skopje, was held the celebration of December 3rd, the International Day of Persons with Disabilities, in organization of the Institute of Special Education and Rehabilitation. The official part of the program was started with a speech by Goran Ajdinski, PhD, the Dean of the Faculty of Philosophy in Skopje. The guests at the celebration were also greeted by the Rector of the University “Ss. Cyril and Methodius” – Skopje, Nikola Jankulovski, PhD and the Minister of Labor and Social Policy of Republic of Macedonia, Frosina Tashevska-Remenski, PhD. After the speeches, which highlighted the current efforts and future commitment to inclusion and accessibility of persons with disabilities, two awards were presented by the Humanitarian foundation “Prof. d-r Ljupco Ajdinski”. The first award was given to Simona Kostadinova as the student with achieved highest grade point average of 9.65 in the generation 2011/12 during the studies of Special education and rehabilitation. The second award was intended for the highest ranked student at the university admission in 2016/2017. This award belonged to Nadica Gjerasimova who had 97.70 points on the official rank list. Beside the awards, two acknowledgements for humanity were also given by the Foundation “Prof. d-r Ljupco Ajdinski”. For the longstanding human activity in preparation of special education and rehabilitation staff and education and rehabilitation of persons with disabilities, the first acknowledgement was given to the Institute of Special education and rehabilitation. The second acknowledgement was meant for Kiril Temkov, PhD, about his numerous initiated and organized human activities, especially for the published paper on the ethical dimensions of special education and rehabilitation and introduction of Ethics in the education system in Republic of Macedonia. The last part of the program was intended for

  20. Do 2nd and 3rd Grade Teachers' Linguistic Knowledge and Instructional Practices Predict Spelling Gains in Weaker Spellers?

    Science.gov (United States)

    Puliatte, Alison; Ehri, Linnea C.

    2018-01-01

    The relationship between 2nd and 3rd grade teachers' linguistic knowledge and spelling instructional practices and their students' spelling gains from fall to spring was examined. Second grade (N = 16) and 3rd grade (N = 16) teachers were administered an instructional practices survey and a linguistic knowledge test. Total scores on the two…

  1. Preoperative and Postoperative (1st and 3rd Month Metabolic Data of Patients Who Underwent Bariatric Surgery

    Directory of Open Access Journals (Sweden)

    Nilüfer Özdemir Kutbay

    2015-03-01

    Full Text Available Purpose: The growing prevalence of obesity has become a major concern. The efficacy of medical treatment, diet and behavior therapy in morbidly obese patients is limited. Obesity surgery is a treatment option for selected morbidly obese patients. Material and Method: Data of 47 patients (n=39 women, 8 men who underwent bariatric surgery were investigated. Results: Out of 47 patients, 20 underwent Roux-en-Y gastric bypass (RYGB (43% and 27 had sleeve gastrectomy (SG (57%. The mean age of the patients was 37±9.5 (19-59 years. 17% of patients were men and 83% were women. In the analysis of data on weight that could be found for 31 out of 47 patients, we detected preoperative and postoperative (1st and 3rd month mean weight values as 125.4±15.9 kg, 112.7±13.2 kg (p<0.001 and 100.9±17.5 kg (p<0.001, respectively. In addition, the analysis of the data on mean fasting plasma glucose (FPG levels which could be found for 23 out of 47 patients, showed us that preoperative and postoperative (1st and 3rd month FPG levels were 100.9±17.5 mg/dL, 91.6±10.9 mg/dL (p=0.03 and 87.3±2.0 mg/dL, respectively. Only 1 patient had diabetes before the surgery. In the RYGB group, the mean change in weight was 12.4±5.5 kg in the 1st month and 22.2±8.6 kg in the 3rd month (compared to the weights in the preoperative period. Moreover, in the SG group, the mean change in weight was 13.7±4.5 kg in the 1st month and 23.4±5.8 kg in the 3rd month. No statistically significant difference was found between the weight changes in the 1st and the 3rd month as for surgery types. Discussion: After bariatric surgery, significant loss in weight and reduction in FPG occurred in short-term.

  2. 3rd International School of Trigger and Data Acquisition - Cracow (Poland), 1 – 8 February 2012

    CERN Multimedia

    Yi Ling

    2011-01-01

    After two successful editions of the International School of Trigger and Data Acquisition (ISOTDAQ), the ISOTDAQ 2012 is the third of a series of this International School dedicated to introduce MSc and PhD students to the arts and crafts of triggering and acquiring data for physics experiments. The school will be held from 1 – 8 February 2012 in the Cracow University of Technology and Institute of Nuclear Physics, Cracow, Poland.  The school provides an up-to-date overview of the basic instruments and methodologies used in high energy physics, spanning from small experiences in lab to the very large LHC experiments, spotting the main building blocks as well as the different solutions and architectures at different levels of complexity. The main topics of the school include the basics of Data Acquisition (DAQ) programming concepts (e.g. threaded programming, data storage, networking, IO programming), hardware bus systems (VME bus, PCI), Trigger logic and Hardware (NIM). PC based readout...

  3. genome editing

    Indian Academy of Sciences (India)

    2016-02-11

    Feb 11, 2016 ... The background of this 'linguistic turn' is the discovery of the CRISPR Cas9 system and its possible applications, which are described in two previous publications (Morange. 2015a, b). 2. The early uses of 'editing'. All molecular biologists are familiar with the phenomenon of. RNA editing discovered in the ...

  4. 3rd Quarter Transportation Report FY2015: Radioactive Waste Shipments to and from the Nevada National Security Site (NNSS)

    Energy Technology Data Exchange (ETDEWEB)

    Gregory, Louis B. [National Security Technologies, LLC (NSTec), Las Vegas, NV (United States)

    2015-07-01

    This report satisfies the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) commitment to prepare a quarterly summary report of radioactive waste shipments to and from the Nevada National Security Site (NNSS) Radioactive Waste Management Complex (RWMC) at Area 5. There were no shipments sent for offsite treatment and returned to the NNSS this quarter. This report summarizes the 3rd quarter of Fiscal Year (FY) 2015 low-level radioactive waste (LLW) and mixed low-level radioactive waste (MLLW) shipments.

  5. Influence of solar eclipse of November 3rd, 2013 on the total ozone column over Badajoz, Spain

    CERN Document Server

    Mateos, D; Vaquero, J M

    2014-01-01

    The hybrid eclipse of November 3rd, 2013 was observed as partial with a magnitude equal to 0.126 from Badajoz (38^\\circ 53' N, 6^\\circ 58' W). The evolution of the Total Ozone Column (TOC) values during 4 hours was monitored using a Solar Light Microtops-II manual sun-photometer. Before the eclipse, TOC remained invariable ~280 Dobson Units (DU) for one hour and a half. Once the eclipse was started, a clear decrease in TOC occurred. After the eclipse maximum (with TOC = 273 DU), a rapid TOC recovery was observed. When the eclipse was over, TOC came back to values ~280 DU.

  6. TUMULI, ROADS AND PLOTS. DECODING THE MONUMENTAL FUNERARY SPACE OF THE 4TH-3RD CENTURIES BC KALLATIS

    Directory of Open Access Journals (Sweden)

    Maria Magdalena Ștefan

    2017-03-01

    Full Text Available The study focusses on the monumental elements of the 4th-3rd centuries BC cemeteries of Kallatis: the use of large tumuli, the implementation of a systematized network of funerary plots, the extent of the burial grounds, the discovery of a series of built chamber tombs under tumuli with elements of decorated architecture, including mural paintings and exceptional presence of a statue topping a tumulus. The detection and morphological characterisation of archaeological features and the recovering of the funerary landscapes’ spatial layout were based on historiographic study, remote-sensing and geophysical investigations.

  7. What difference does a year of schooling make?: Maturation of brain response and connectivity between 2nd and 3rd grades during arithmetic problem solving

    OpenAIRE

    Rosenberg-Lee, Miriam; Barth, Maria; Menon, Vinod

    2011-01-01

    Early elementary schooling in 2nd and 3rd grades (ages 7-9) is an important period for the acquisition and mastery of basic mathematical skills. Yet, we know very little about neurodevelopmental changes that might occur over a year of schooling. Here we examine behavioral and neurodevelopmental changes underlying arithmetic problem solving in a well-matched group of 2nd (n = 45) and 3rd (n = 45) grade children. Although 2nd and 3rd graders did not differ on IQ or grade- and age-normed measure...

  8. AN ANALYSIS OF STUDENTS’ SPEAKING ABILITY IN ENGLISH CONVERSATION CLUB (ECC PROGRAM AT THE 3rd SEMESTER

    Directory of Open Access Journals (Sweden)

    M. Fadhly Farhy Abbas

    2017-07-01

    Full Text Available This research is based on students’ speaking ability who had followed the EnglishConversation Club (ECC program especially for the third semester of English Department. Thepurpose of this study was to analyze the students’ speaking ability at the 3rd semester in the EnglishConversation Club FKIP UNILAK Pekanbaru. The type of the research was mixed method in typeof explanatory design. The number of participant was 53 students. The researcher used twoinstruments, those were test and interview. In analyzing the data, it used in descriptive statistics.The result of the analysis showed that the average score of 3rd semester students’ speaking abilitywas 45.42. It can be concluded that the students’ speaking ability was categorized into failed . Thescore of Standard Deviation was 7.02, Variance was 49.30, and Range was 36 points . It meansthat the students’ speaking ability was homogeneous. According to the Z-Score, it can be seen that49.06% students’ ability was higher than average and 50.94% students ability was below theaverage. In conclusion, the students’ ability in learning speaking English was failed, it had beenaffected by some factors, those were lack of vocabulary, grammar and motivation. It was supportedby the interview, eventhough the students’ perception to English Conversation Club (ECCprogram was positive, but in fact, the students’ frequency to speak English was seldom, they wereless practice speaking English everyday.Keywords : Speaking , English Conversation Club (ECC

  9. The 3rd Global Summit of Research Institutes for Disaster Risk Reduction:Expanding the Platform for Bridging Science and Policy Making

    National Research Council Canada - National Science Library

    Andrew Collins Hirokazu Tatano Wilma James Chadia Wannous Kaoru Takara Virginia Murray Charles Scawthorn Jim Mori Sarah Aziz Khalid M.Mosalam Stefan Hochrainer-Stigler Irasema Alcántara-Ayala Elisabeth Krausmann Wei-Sen Li Ana Maria Cruz Subhajyoti Samaddar Tom De Groeve Yuichi Ono Kelvin Berryman Koji Suzuki Mark Ashley Parry Peter McGowran John G.Rees

    2017-01-01

    The Global Alliance of Disaster Research Institutes held its 3rd Global Summit of Research Institutes for Disaster Risk Reduction at the Disaster Prevention Research Institute,Kyoto University,Japan,19–21 March,2017...

  10. Performance characteristics of the Beckman Coulter UniCel DxI 800 TSH (3rd IS) assay.

    Science.gov (United States)

    Winston-McPherson, Gabrielle N; Samraj, Annie N; Poster, Kristina; Yamaguchi, Diane; Dickerson, Jane A; Drees, Julia C; Holmes, Daniel T; Greene, Dina N

    2018-03-01

    Beckman Coulter recently reformulated their commercial TSH assay with primary calibration to the World Health Organization 3rd TSH international standard. An extensive evaluation of the performance characteristics for this assay was completed. Intra-day and inter-day precision was evaluated using 3 concentrations of commercial quality control material. Linearity, reportable range, stability, sensitivity and susceptibility to common inferences were determined using pooled patient specimens. Inter-assay variability was assessed across 5 different platforms (n=47 patient specimens). Intra-day and inter-day CVs were UniCel DxI 800, is precise, highly sensitive and comparable to the previous generation assay. The assay is acceptable for clinical testing. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. THE 3rd SCHIZOPHRENIA INTERNATIONAL RESEARCH SOCIETY CONFERENCE, 14-18 APRIL 2012, FLORENCE, ITALY: SUMMARIES OF ORAL SESSIONS

    Science.gov (United States)

    Abbs, Brandon; Achalia, Rashmin M; Adelufosi, Adegoke O; Aktener, Ahmet Yiğit; Beveridge, Natalie J; Bhakta, Savita G; Blackman, Rachael K; Bora, Emre; Byun, MS; Cabanis, Maurice; Carrion, Ricardo; Castellani, Christina A; Chow, Tze Jen; Dmitrzak-Weglarz, M; Gayer-Anderson, Charlotte; Gomes, Felipe V; Haut, Kristen; Hori, Hiroaki; Kantrowitz, Joshua T; Kishimoto, Taishiro; Lee, Frankie HF; Lin, Ashleigh; Palaniyappan, Lena; Quan, Meina; Rubio, Maria D; Ruiz de Azúa, Sonia; Sahoo, Saddichha; Strauss, Gregory P; Szczepankiewicz, Aleksandra; Thompson, Andrew D; Trotta, Antonella; Tully, Laura M; Uchida, Hiroyuki; Velthorst, Eva; Young, Jared W; O’Shea, Anne; DeLisi, Lynn E.

    2013-01-01

    The 3rd Schizophrenia International Research Society Conference was held in Florence, Italy, April 14-18, 2012.and this year had as its emphasis, “The Globalization of Research”. Student travel awardees served as rapporteurs for each oral session and focused their summaries on the most significant findings that emerged and the discussions that followed. The following report is a composite of these summaries. We hope that it will provide an overview for those who were present, but could not participate in all sessions, and those who did not have the opportunity to attend, but who would be interested in an update on current investigations ongoing in the field of schizophrenia research. PMID:22910407

  12. Color Portion of Solar Radiation in the Partial Annular Solar Eclipse, October 3rd, 2005, at Helwan, Egypt

    Directory of Open Access Journals (Sweden)

    A. H. Hassan

    2010-01-01

    Full Text Available Measurements were made of various solar radiation components, global, direct and diffuse and their fractions during the partial annular solar eclipse on October 3rd, 2005 at Helwan, Egypt (Lat. 29.866◦ N and Long. 31.20◦ E, and an analysis has been made. The duration of the solar eclipse was 3 h 17 min, and the maximum magnitude of the eclipse in this region was 0.65. The optical depth of the direct component and the relative humidity decreased, while both the transparency and the air temperature increased towards the maximum eclipse. The general trends of the global components are decreasing optical depth and increasing transparency between the first contact and the last contact. The prevailing color during the eclipse duration was diffused infrared (77 % of the total diffuse radiation level.

  13. Thymiateria on the coast. Shrines, pilgrimages and rituals in Iberian Contestania (3rd-2nd centuries BC

    Directory of Open Access Journals (Sweden)

    Jorge GARCÍA CARDIEL

    2015-11-01

    Full Text Available This paper aims to study three sites of complex interpretation located along the Alicante coast and dated back to the late Iberian period (also known as ‘Ibero-Roman period’: the “shrine” area of Tossal de la Cala (Benidorm, Castillo de Guardamar (Guardamar del Segura, and the most ancient phase of La Malladeta (La Vila Joiosa. Available fragmentary data are treated from the point of view of some considerations developed by the Landscape Archaeology, the Postcolonial Theory, the Social Theory and the Anthropology. This paper argues that the three sites would act as coastal suburban shrines between 3rd and 2nd centuries bc. There are vestiges of the same kind of rituals in all of them: the amortization of table ware and amphorae, and the offering of female bust thymiateria. These spaces may privilege the community cohesion and its territorial claims in the critical context of the Punic occupation and the Roman provincialisation.

  14. Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria; third edition (M45, 3rd ed.)

    National Research Council Canada - National Science Library

    Bernard, Kathryn

    2015-01-01

    "This guideline informs clinical, public health, and research labortories on susceptibility testing of infrequently isolated or fastidious bacteria that are not included in CLSI documents M02, M07, or M100...

  15. Reliability and validity of the Spanish Language Wechsler Adult Intelligence Scale (3rd Edition) in a sample of American, urban, Spanish-speaking Hispanics.

    Science.gov (United States)

    Renteria, Laura; Li, Susan Tinsley; Pliskin, Neil H

    2008-05-01

    The utility of the Spanish WAIS-III was investigated by examining its reliability and validity among 100 Spanish-speaking participants. Results indicated that the internal consistency of the subtests was satisfactory, but inadequate for Letter Number Sequencing. Criterion validity was adequate. Convergent and discriminant validity results were generally similar to the North American normative sample. Paired sample t-tests suggested that the WAIS-III may underestimate ability when compared to the criterion measures that were utilized to assess validity. This study provides support for the use of the Spanish WAIS-III in urban Hispanic populations, but also suggests that caution be used when administering specific subtests, due to the nature of the Latin America alphabet and potential test bias.

  16. Cluster editing

    DEFF Research Database (Denmark)

    Böcker, S.; Baumbach, Jan

    2013-01-01

    The Cluster Editing problem asks to transform a graph into a disjoint union of cliques using a minimum number of edge modifications. Although the problem has been proven NP-complete several times, it has nevertheless attracted much research both from the theoretical and the applied side. The prob......The Cluster Editing problem asks to transform a graph into a disjoint union of cliques using a minimum number of edge modifications. Although the problem has been proven NP-complete several times, it has nevertheless attracted much research both from the theoretical and the applied side....... The problem has been the inspiration for numerous algorithms in bioinformatics, aiming at clustering entities such as genes, proteins, phenotypes, or patients. In this paper, we review exact and heuristic methods that have been proposed for the Cluster Editing problem, and also applications...

  17. 3rd Cryocooler Conference

    CERN Document Server

    Louie, Berverly; McCarthy, Sandy

    1985-01-01

    Cryocoolers 3 documents the output of the Third Cryocooler Conference, held at the National Bureau of Standards, Boulder, Colorado, on September 17-18, 1984. About 140 people from 10 countries attended the conference representing industry, government, and academia. A total of 26 papers were presented orally at the conference and all appear in written form in the proceedings. The focus of this conference was on small cryocoolers in the temperature range of 4 - 80 K. Mechanical and nonmechanical types are discussed in the various papers. Applications of these small cryocoolers include the cooling of infrared detectors, cryopumps, small superconducting devices and magnets, and electronic devices. The conference proceedings reproduced here was published by the National Bureau of Standards in Boulder, Colorado as NBS Special Publication #698.

  18. 3rd SAGA Workshop

    CERN Document Server

    Conti, Giuseppe

    2014-01-01

    Mathematical algorithms are a fundamental component of Computer Aided Design and Manufacturing (CAD/CAM) systems. This book provides a bridge between algebraic geometry and geometric modelling algorithms, formulated within a computer science framework. Apart from the algebraic geometry topics covered, the entire book is based on the unifying concept of using algebraic techniques – properly specialized to solve geometric problems – to seriously improve accuracy, robustness and efficiency of CAD-systems. It provides new approaches as well as industrial applications to deform surfaces when animating virtual characters, to automatically compare images of handwritten signatures, and to improve control of NC machines. This book further introduces a noteworthy representation based on 2D contours, which is essential to model the metal sheet in industrial processes. It additionally reviews applications of numerical algebraic geometry to differential equations systems with multiple solutions and bifurcations. Futur...

  19. 3rd Dynamics Days

    CERN Document Server

    Clerc, Marcel

    2016-01-01

    This book presents recent advances, new ideas and novel techniques related to the field of nonlinear dynamics, including localized pattern formation, self-organization and chaos. Various natural systems ranging from nonlinear optics to mechanics, fluids and magnetic are considered. The aim of this book is to gather specialists from these various fields of research to promote cross-fertilization and transfer of knowledge between these active research areas. In particular, nonlinear optics and laser physics constitute an important part in this issue due to the potential applications for all-optical control of light, optical storage, and information processing. Other possible applications include the generation of ultra-short pulses using all-fiber cavities.

  20. 3rd Abel Symposium

    CERN Document Server

    Owren, Brynjulf

    2008-01-01

    The 2006 Abel symposium is focusing on contemporary research involving interaction between computer science, computational science and mathematics. In recent years, computation has been affecting pure mathematics in fundamental ways. Conversely, ideas and methods of pure mathematics are becoming increasingly important within computational and applied mathematics. At the core of computer science is the study of computability and complexity for discrete mathematical structures. Studying the foundations of computational mathematics raises similar questions concerning continuous mathematical structures. There are several reasons for these developments. The exponential growth of computing power is bringing computational methods into ever new application areas. Equally important is the advance of software and programming languages, which to an increasing degree allows the representation of abstract mathematical structures in program code. Symbolic computing is bringing algorithms from mathematical analysis into the...

  1. Franquismo y Vanguardia: III Bienal Hispanoamericana de Arte = Francoism and avant-garde: the 3rd Hispanoamerican Biennial of Art

    Directory of Open Access Journals (Sweden)

    Eva March Roig

    2015-01-01

    Full Text Available Durante los meses de octubre, noviembre y diciembre de 1955 Barcelona acogió la “III Bienal Hispanoamericana de Arte”. Una exposición que no sólo permitió ver la obra más reciente de los artistas españoles e iberoamericanos o una muestra de precursores del arte moderno sino también el arte más nuevo que se estaba haciendo en los Estados Unidos. Por este y por otros muchos motivos, la Bienal significó el triunfo en España de las tendencias abstractas y su absoluto reconocimiento oficial. El objetivo de este trabajo es reconstruir el escenario de ese momento en Barcelona para probar que la III Bienal fue mucho más que un conjunto de exposiciones artísticas. Las iniciativas paralelas que se organizaron en la ciudad, el eco que la prensa les dio, el apabullante éxito de público que tuvieron y el interés que despertaron en ámbitos muy diferentes a los específicamente artísticos, indican que la Bienal fue un acontecimiento que sirvió para acercar, como nunca antes, el arte contemporáneo a la sociedad; una sociedad que, a partir de entonces, estaría más formada para recibir y concebir nuevos discursos artísticos.During the months of October, November and December of 1955 Barcelona hosted the 3rd Hispanoamerican Biennial of Art. An exhibition that not only permitted us to see the most recent works by Spanish and Hispanoamerican artists or an exposition of the forefathers of modern art but also the latest art that was being produced in the United States. For this and many other reasons, the Biennial meant a triumph in Spain of the abstract trend and its absolute official recognition.The aim of this paper is to reconstruct the scene in Barcelona at this moment in order to prove that the 3rd Biennial was much more than a collection of art exhibitions. The parallel events that were organized in the city, the coverage that the press gave it, the outstanding success achieved with the public, and the interest that was

  2. Textiles in a social context. Textile production in Europe and the Mediterranean in the 4th and 3rd millennia BCE (Session report)

    DEFF Research Database (Denmark)

    Siennicka, Malgorzata; Rahmstorf, Lorenz; Ulanowska, Agata

    2015-01-01

    A report of the regular session "Textiles in a social context. Textile production in Europe and the Mediterranean in the 4th and 3rd millennia BCE" at the 20th Annual EAA Conference in Istanbul, Turkey, 10-14/09/2014......A report of the regular session "Textiles in a social context. Textile production in Europe and the Mediterranean in the 4th and 3rd millennia BCE" at the 20th Annual EAA Conference in Istanbul, Turkey, 10-14/09/2014...

  3. Influence of radiofrequency-electromagnetic waves from 3rd-generation cellular phones on fertilization and embryo development in mice.

    Science.gov (United States)

    Suzuki, Satoshi; Okutsu, Miho; Suganuma, Ryota; Komiya, Hiromi; Nakatani-Enomoto, Setsu; Kobayashi, Shunsuke; Ugawa, Yoshikazu; Tateno, Hiroyuki; Fujimori, Keiya

    2017-09-01

    The purpose of this study was to evaluate the effects of 3rd-generation (3G) cellular phone radiofrequency-electromagnetic wave (RF-EMW) exposure on fertilization and embryogenesis in mice. Oocytes and spermatozoa were exposed to 3G cellular phone RF-EMWs, 1.95 GHz wideband code division multiple access, at a specific absorption rate of 2 mW/g for 60 min, or to sham exposure. After RF-EMW exposure, in vitro fertilization and intracytoplasmic sperm injection were performed. Rates of fertilization, embryogenesis (8-cell embryo, blastocyst), and chromosome aberration were compared between the combined spermatozoa and oocyte groups: both exposed, both non-exposed, one exposed, and the other non-exposed. Rates of fertilization, embryogenesis, and blastocyst formation did not change significantly across the four groups. Considering that the degree of exposure in the present study was ≥100 times greater than daily exposure of human spermatozoa and even greater than daily exposure of oocytes, the present results indicate safety of RF-EMW exposure in humans. Bioelectromagnetics. 38:466-473, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  4. Ultrastructure of the ovary of Dermatobia hominis (Diptera: cuterebridae. I. Development during the 3rd larval instar

    Directory of Open Access Journals (Sweden)

    E. A. Gregorio

    1990-09-01

    Full Text Available The ultrastructure and distribution of gonial and somatic cells in the ovary of Dermatobia hominis was studied during the 3rd larval instar. In larvae weighing between 400 and 500 mg, the ovary is partially divided into basal and apical regions by oblong somatic cells that penetrate from the periphery; these cells show ovoid nucleus and cytoplasm full of microtubules. In both regions, gonial cells with regular outlines, large nucleus and low electron-density cytoplasm are scattered among the interstitial somatic cells. These later cells have small nucleus and electrodense cytoplasm. Clear somatic cells with small nucleus and cytoplasm of very low electron-density are restrict to the apical region of the gonad. Degenerating interstitial somatic cells are seen in the basal portion close to the ovary peduncle. During all this larval period the morphological features of the ovary remain almost the same. At the end of the period there is a gradual deposition of glycogen in the cytoplasm of the somatic cells, increase in the number and density of their mitochondria plus nuclear modification as membrane wrinkling and chromatin condensation in masses.

  5. The 3rd Canadian Symposium on Hepatitis C Virus: Expanding Care in the Interferon-Free Era

    Directory of Open Access Journals (Sweden)

    Sonya A MacParland

    2014-01-01

    Full Text Available Hepatitis C virus (HCV currently infects approximately 250,000 individuals in Canada and causes more years of life lost than any other infectious disease in the country. In August 2011, new therapies were approved by Health Canada that have achieved higher response rates among those treated, but are poorly tolerated. By 2014/2015, short-course, well-tolerated treatments with cure rates >95% will be available. However, treatment uptake is poor due to structural, financial, geographical, cultural and social barriers. As such, ‘Barriers to access to HCV care in Canada’ is a crucial topic that must be addressed to decrease HCV disease burden and potentially eliminate HCV in Canada. Understanding how to better care for HCV-infected individuals requires integration across multiple disciplines including researchers, clinical services and policy makers to address the major populations affected by HCV including people who inject drugs, baby boomers, immigrants and Aboriginal and/or First Nations people. In 2012, the National CIHR Research Training Program in Hepatitis C organized the 1st Canadian Symposium on Hepatitis C Virus (CSHCV in Montreal, Quebec. The 2nd CSHCV was held in 2013 in Victoria, British Columbia. Both symposia were highly successful, attracting leading international faculty with excellent attendance leading to dialogue and knowledge translation among attendees of diverse backgrounds. The current article summarizes the 3rd CSHCV, held February 2014, in Toronto, Ontario.

  6. [Evaluation of the Marburg Spelling Training (MRT) in 2nd- and 3rd-grade students with spelling difficulties].

    Science.gov (United States)

    Barkmann, Claus; Kuhlmann, Ester; Rosenboom, Lea; Wessolowski, Nino; Schulte-Markwort, Michael

    2012-05-01

    Children with severe dyslexia are substantially impaired because reading and writing are key competencies necessary for a successful academic and occupational career. In this evaluation study, a cohort of 2nd- and 3rd-grade students from a variety of Hamburg primary schools was trained with the Marburger Rechtschreibtraining (MRT) by supervised university graduates. The research questions focused on the feasibility of the MRT as a within-school training, the improvement of spelling and reading skills of the participants, subjective assessments of success, as well as potential predictors. Besides established performance tests, we also considered the subjective appraisals of parents, teachers, and coaches. The results demonstrate that standardized spelling training methods like the MRT can be consistently used during morning hours at schools. Within a year of starting MRT exercises, mean effect sizes in writing and reading were observed in performance tests using test norms. However, parent, teacher, and coach reports failed to replicate these improvements. Changes in writing performance were mainly associated with school class level; improvements in reading ability were dependent on initial writing performance. The results provide starting points for optimizing current training practices in elementary schools and for posing questions regarding the effectiveness of the MRT, as well as for training programs in general.

  7. 3rd Quarter Transportation Report FY 2014: Radioactive Waste Shipments to and from the Nevada National Security Site (NNSS)

    Energy Technology Data Exchange (ETDEWEB)

    Gregory, Louis [National Security Technologies, LLC. (NSTec), Mercury, NV (United States)

    2014-09-20

    This report satisfies the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) commitment to prepare a quarterly summary report of radioactive waste shipments to the Nevada National Security Site (NNSS) Radioactive Waste Management Complex (RWMC) at Area 5. There were no shipments sent for offsite treatment and returned to the NNSS this quarter. This report summarizes the 3rd quarter of Fiscal Year (FY) 2014 low-level radioactive waste (LLW) and mixed low-level radioactive waste (MLLW) shipments. This report also includes annual summaries for FY 2014 in Tables 4 and 5. Tabular summaries are provided which include the following: Sources of and carriers for LLW and MLLW shipments to and from the NNSS; Number and external volume of LLW and MLLW shipments; Highway routes used by carriers; and Incident/accident data applicable to LLW and MLLW shipments. In this report shipments are accounted for upon arrival at the NNSS, while disposal volumes are accounted for upon waste burial. The disposal volumes presented in this report do not include minor volumes of non-radioactive materials that were approved for disposal. Volume reports showing cubic feet generated using the Low-Level Waste Information System may vary slightly due to differing rounding conventions.

  8. From bottom to top: Identification to precision measurement of 3rd-generation quarks with the atlas detector

    Science.gov (United States)

    Sapp, Kevin

    The 3rd-generation quarks, bottom ( b) and top (t), are recent additions to the Standard Model of particle physics, and precise characterization of their properties have important implications to searching for new physics phenomena. This thesis presents two analyses which use 4.6 fb-1 of pp collision data at √s = 7 TeV collected by the ATLAS detector at the Large Hadron Collider (LHC) to measure their properties. The first is an analysis which measures our ability to identify jets originating from b quarks with machine-learning algorithms applied to simulated and real data, so the result in simulation can be corrected to match that in data. This measurement has implications for our ability to identify processes with b quarks in their final state; t quarks decay to a b quark and a weak vector boson W more than 99% of the time. The second analysis presented measures properties of the t → Wb decay channel associated with phenomena not predicted by the Standard Model, through a set of effective couplings which preserve Lorentz covariance. The kinematic information of the final-state particles is used to construct an event-specific coordinate system, and probability density is estimated as a function of solid angle in these coordinates. A parameterization of the effective couplings is extracted via a novel unfolding method, finding their values consistent with the Standard Model expectation, contributing the first measurement of the correlation between the parameters, and improving on previous limits.

  9. From Bottom to Top: Identification to Precision Measurement of 3rd-Generation Quarks with the ATLAS Detector

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00335926

    The 3rd-generation quarks, bottom ($b$) and top ($t$), are recent additions to the Standard Model of particle physics, and precise characterization of their properties have important implications to searching for new physics phenomena. This thesis presents two analyses which use 4.6 fb$^{-1}$ of $pp$ collision data at $\\sqrt{s} = 7$ TeV collected by the ATLAS detector at the Large Hadron Collider (LHC) to measure their properties. The first is an analysis which measures our ability to identify jets originating from $b$ quarks with machine-learning algorithms applied to simulated and real data, so the result in simulation can be corrected to match that in data. This measurement has implications for our ability to identify processes with b quarks in their final state; $t$ quarks decay to a $b$ quark and a weak vector boson $W$ more than 99% of the time. The second analysis presented measures properties of the $t \\rightarrow Wb$ decay channel associated with phenomena not predicted by the Standard Model, through...

  10. Technical Optimization of Cross-Platform Software Development Process quality and Usability of 3rd-Party Tools

    Directory of Open Access Journals (Sweden)

    Yevgueny Kondratyev

    2016-03-01

    Full Text Available The article exposes developer's point of view on minimizing creation, upgrade, post-release problem solving time for applications and components, targeted to multiple operating systems, while keeping high end product quality and computational performance. Non-uniformity of analogous tools and components, available on different platforms, causes strong impact on developer's productivity. In part., differences in 3rd-party component interfaces, versions, quality of distinct functions, cause frequent switching developer's attention on issues not connected (in principle with the target project. While loss of development performance because of attention specifics is more subjective value, at least physical time spent on tools/components misbehavior compensation and normal tools configuring is measurable. So, the main thesis verified is whether it's possible to increase continuity of the development process by technical improvements only, and by which value. In addition, a novel experimental tool for interactive code execution is described, allowing for deep changes in the working program without its restart. Question under research: minimizing durations of programming-build-test-correct loop and small code parts runs, in part., improving the debugging workflow for the account of combining the interactive editor and the debugger.

  11. Specificity and sensitivity of 3rd generation EIA for detection of HCV antibodies among intravenous drug-users.

    Science.gov (United States)

    Filice, G; Patruno, S; Campisi, D; Chiesa, A; Orsolini, P; Debiaggi, M; Bruno, R; Tinelli, M

    1993-01-01

    Serum samples from 487 ambulatory I.V. drug users were screened for HIV and HCV antibodies to determine the prevalence of coinfection in this high risk group for AIDS. For anti-HCV antibody screening we first used a 3rd generation EIA using, as antigen synthetic peptides which were not subjected to false positive results due to antibodies against superoxide dismutase or against yeast proteins (which may copurify with the recombinant proteins employed in the first and second generation test). The specimens that were positive in the screening test were confirmed by a more specific EIA system that detect antibodies to proteins encoded by structural (HCV-st EIA) and non structural (HCV-nst-EIA) regions of the HCV genome. A second confirmation assay was also performed: sera were run in presence or absence of blocking reagents which inhibits antibodies to C200 and C22 HCV epitopes for binding to the solid phase. The sensitivity of the HCV EIA screening for human HCV antibody detection revealed a 100% positivity for HCV infection. The confirmatory strategy presented in this paper revealed an HCV EIA specificity of 98.6%. In this work we demonstrated a significantly higher prevalence (p HIV infected individuals compared to the general population. Our experimental data also confirmed that HBV infection in drug-users at high risk for HIV infection was significantly associated with HCV infection (p HIV by sexual contact was not a statistically significant risk factor for HCV coinfection.

  12. Proceedings of the 3rd Expert Consultation and Planning Meeting on Infant and Young Child Nutrition--(Part 2).

    Science.gov (United States)

    Amarra, Sofia; Chan, Pauline

    2013-04-01

    The Infant and Early Childhood Nutrition Task Force, International Life Sciences Institute Southeast Asia (ILSI SEA) Region, organised the 1st and 2nd Expert Consultation and Planning Meeting on Infant and Early Childhood Nutrition in 2009 and 2011, respectively. The goal of the consultations was "to generate and promote relevant science-based information that will help improve nutritional status, growth and development of infants and young children in Southeast Asia." An Expert Panel Core Group was created whose role is to provide advice and recommendations through a review of current scientific knowledge regarding issues related to early childhood growth and nutrition. The Panel is composed of experts representing 7 countries (China, Indonesia, Malaysia, Philippines, Singapore, Thailand, and Vietnam). In July 2012, the Panel convened the 3rd Expert Consultation and Planning Meeting on Infant and Young Child Nutrition in Singapore. This report presents the highlights of the meeting and recommendations made by the Panel on ways to improve infant and young child nutrition in Southeast Asia. The effective use of WHO indicators for assessing infant and young child feeding practices, mitigating the effects of maternal employment on breastfeeding, using behaviour change communication, updating the education of health personnel, and improving maternal health were considered important actions to be taken. Since current feeding practices in Southeast Asia fall short of WHO recommendations, studies are needed to develop strategies which take into consideration the diverse cultural settings that characterise the region.

  13. The microstructural evolution and elemental distribution of a 3rd generation 1 GPa advanced high strength steel during double pulse resistance spot welding

    NARCIS (Netherlands)

    Eftekharimilani, P.; van der Aa, EM; Hermans, M.J.M.; Richardson, I.M.

    2017-01-01

    This paper presents the effects of double pulse resistance spot welding (RSW) on the microstructural evolution, elemental distribution and mechanical properties of a 3rd generation 1 GPa advanced high strength steel (AHSS). In order to investigate the effect of double pulsing, the steel was exposed

  14. Effectively utilising a 3rd party 3D visualization component in a discrete event simulation environment for Joint Command and Control (JC2)

    CSIR Research Space (South Africa)

    Ramadeen, P

    2009-09-01

    Full Text Available A 3rd party 3-dimensional visualization tool (developed by the Council for Scientific and Industrial Research (CSIR)) is being used to visualize and assist with the development of a synthetic environment for joint command and control technology...

  15. for video describing a prestigious Government of Canada prize which the Canadian team in ALPHA will be awarded on February 3rd

    CERN Multimedia

    2013-01-01

    Footage for video describing a prestigious Government of Canada prize which the Canadian team in ALPHA will be awarded on February 3rd 2014. On the video: -Mic-Michael Hayden (Simon Fraser Univ.) -Walter Hardy (Univ. of British Columbia) -Andrea Capra (York Univ.)hael Hayden (Simon Fraser Univ.)

  16. Some problems in the study of the chronology of the ancient nomadic cultures in Eurasia (9th - 3rd Centuries BC).

    NARCIS (Netherlands)

    Alekseev, A.Yu.; Bokovenko, N.A.; Boltrik, Yu.; Chugunov, K.A.; Cook, G.; Dergachev, V.A.; Kovaliukh, N.; Possnert, G.; Plicht, J. van der; Scott, E.M.; Sementsov, A.; Skripkin, V.; Vasiliev, S.; Zaitseva, G.

    2002-01-01

    This research is focused on the chronological investigations of ancient nomads belonging to the Scythian cultures which occupied the steppe and forest-steppe zones of Eurasia during the 9th-3rd centuries BC. The 14C dates for the pre-scythian and early scythian time in both Europe and Asia are

  17. Relationship between gestational age and transabdominal ultrasonographic measurements of fetus and uterus during the 2nd and 3rd trimester of gestation in cows

    Directory of Open Access Journals (Sweden)

    Eman Hayawie Lazim

    2016-07-01

    Conclusion: Transabdominal ultrasonography is a practical and reliable method for obtaining the fetal and uterine measurements during the 2nd and 3rd trimesters of gestation. The correlation coefficients between gestational age and fetal measurements (width of trunk and heart and intercostal distance were higher than those of uterine measurements, and the highest correlation was between heart width and gestational age in cows.

  18. What difference does a year of schooling make? Maturation of brain response and connectivity between 2nd and 3rd grades during arithmetic problem solving.

    Science.gov (United States)

    Rosenberg-Lee, Miriam; Barth, Maria; Menon, Vinod

    2011-08-01

    Early elementary schooling in 2nd and 3rd grades (ages 7-9) is an important period for the acquisition and mastery of basic mathematical skills. Yet, we know very little about neurodevelopmental changes that might occur over a year of schooling. Here we examine behavioral and neurodevelopmental changes underlying arithmetic problem solving in a well-matched group of 2nd (n = 45) and 3rd (n = 45) grade children. Although 2nd and 3rd graders did not differ on IQ or grade- and age-normed measures of math, reading and working memory, 3rd graders had higher raw math scores (effect sizes = 1.46-1.49) and were more accurate than 2nd graders in an fMRI task involving verification of simple and complex two-operand addition problems (effect size = 0.43). In both 2nd and 3rd graders, arithmetic complexity was associated with increased responses in right inferior frontal sulcus and anterior insula, regions implicated in domain-general cognitive control, and in left intraparietal sulcus (IPS) and superior parietal lobule (SPL) regions important for numerical and arithmetic processing. Compared to 2nd graders, 3rd graders showed greater activity in dorsal stream parietal areas right SPL, IPS and angular gyrus (AG) as well as ventral visual stream areas bilateral lingual gyrus (LG), right lateral occipital cortex (LOC) and right parahippocampal gyrus (PHG). Significant differences were also observed in the prefrontal cortex (PFC), with 3rd graders showing greater activation in left dorsal lateral PFC (dlPFC) and greater deactivation in the ventral medial PFC (vmPFC). Third graders also showed greater functional connectivity between the left dlPFC and multiple posterior brain areas, with larger differences in dorsal stream parietal areas SPL and AG, compared to ventral stream visual areas LG, LOC and PHG. No such between-grade differences were observed in functional connectivity between the vmPFC and posterior brain regions. These results suggest that even the narrow one

  19. What difference does a year of schooling make?: Maturation of brain response and connectivity between 2nd and 3rd grades during arithmetic problem solving

    Science.gov (United States)

    Rosenberg-Lee, Miriam; Barth, Maria; Menon, Vinod

    2011-01-01

    Early elementary schooling in 2nd and 3rd grades (ages 7-9) is an important period for the acquisition and mastery of basic mathematical skills. Yet, we know very little about neurodevelopmental changes that might occur over a year of schooling. Here we examine behavioral and neurodevelopmental changes underlying arithmetic problem solving in a well-matched group of 2nd (n = 45) and 3rd (n = 45) grade children. Although 2nd and 3rd graders did not differ on IQ or grade- and age-normed measures of math, reading and working memory, 3rd graders had higher raw math scores (effect sizes = 1.46-1.49) and were more accurate than 2nd graders in an fMRI task involving verification of simple and complex two-operand addition problems (effect size = 0.43). In both 2nd and 3rd graders, arithmetic complexity was associated with increased responses in right inferior frontal sulcus and anterior insula, regions implicated in domain-general cognitive control, and in left intraparietal sulcus (IPS) and superior parietal lobule (SPL) regions important for numerical and arithmetic processing. Compared to 2nd graders, 3rd graders showed greater activity in dorsal stream parietal areas right SPL, IPS and angular gyrus (AG) as well as ventral visual stream areas bilateral lingual gyrus (LG), right lateral occipital cortex (LOC) and right parahippocampal gyrus (PHG). Significant differences were also observed in the prefrontal cortex (PFC), with 3rd graders showing greater activation in left dorsal lateral PFC (dlPFC) and greater deactivation in the ventral medial PFC (vmPFC). Third graders also showed greater functional connectivity between the left dlPFC and multiple posterior brain areas, with larger differences in dorsal stream parietal areas SPL and AG, compared to ventral stream visual areas LG, LOC and PHG. No such between-grade differences were observed in functional connectivity between the vmPFC and posterior brain regions. These results suggest that even the narrow one

  20. [Level of smoking of 3rd and 4th grade students studying health and related factors: follow-up study].

    Science.gov (United States)

    Göktalay, Tuğba; Cengiz Özyurt, Beyhan; Sakar Coşkun, Ayşin; Celik, Pinar

    2011-01-01

    The levels of smoking of 1st and 2nd year students at Faculty of Medicine and Manisa School of Health at Celal Bayar University were investigated in 2006-2007. This study is carried out in order to see if there is a change in the same students' level of smoking while they are in 3rd and 4th year. In addition, the study aimed to examine the factors affecting the level of use and attitudes towards the law effectuated in July 19, 2009. This is a follow-up study with 80.42% return rate. A 26-item structured questionnaire was administered. The participants filled out the questionnaires under supervision of the researchers in their classrooms. The University Institutional Review Board approved the study. The total of participants (263) of the follow-up study included 189 female and 74 male. The rate of experimenting with smoking was 49% with the mean age of 15.7 (SD= 4.01 years). The mean age of experimenting with smoking was the earliest on male students studying at faculty of medicine. The level of smoking was found to be the most on females, studying at faculty of medicine and staying at the dormitory, with smoking parents (plevel of both experimenting and use of smoking has been increased over time. It is suggested that medical students' awareness about the danger of smoking should be raised at earlier grades. In addition, lectures should be offered to students at School of Health and they should be encouraged to unite in order to fight with smoking.

  1. Organizational Support for the 3rd Summer Institute on Complex Plasmas, July 30 – August 8, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Jose L. [Seton Hall University

    2012-07-01

    This grant provided partial funds for American graduate students to attend the 3rd Graduate Summer Institute on Complex Plasmas, which was held from July 30 to August 8, 2012 at Seton Hall University in South Orange, New Jersey. The Graduate Summer Institute is a topical series of instructional workshops held bi-annually on the emerging field of complex plasmas that is jointly organized through a collaboration between American and German-European Union plasmas researchers. This specialized program brings together many of the world's leading researchers in the specialized area of complex plasmas, who freely provide instructional lectures and tutorials on the most recent research and discoveries done in this branch of plasma science. The partial funds provided by this grant helped support the travel and accommodation expenses of the participating American students and tutorial instructors. Partial funds further supported the travel and accommodation of three renown American plasma researchers that provided educational tutorials to the thirty-eight participating students from the United States, Europe, and Asia. The organized program afforded a unique opportunity for the participating American graduate students to learn about and engage more deeply in an area of plasma science that is not studied in any of the graduate educational curriculums provided by universities in the United States of America. The educational experience offered by this program provided the necessary knowledge needed by future American plasma researchers to keep the national plasma research effort on the cutting-edge and keep the national plasma community as a global leader.

  2. Differences in risk factors for 2nd and 3rd degree hypospadias in the National Birth Defects Prevention Study

    Science.gov (United States)

    in 't Woud, Sander Groen; van Rooij, Iris A.L.M.; van Gelder, Marleen M.H.J.; Olney, Richard S.; Carmichael, Suzan L.; Roeleveld, Nel; Reefhuis, Jennita

    2015-01-01

    Background Hypospadias is a frequent birth defect with three phenotypic subtypes. With data from the National Birth Defects Prevention Study, a large, multi-state, population-based, case-control study, we compared risk factors for second and third degree hypospadias. Methods A wide variety of data on maternal and pregnancy-related risk factors for isolated second and third degree hypospadias was collected via computer-assisted telephone interviews to identify potential etiological differences between the two phenotypes. Logistic regression was used to calculate odds ratios including a random effect by study center. Results In total, 1547 second degree cases, 389 third degree cases, and 5183 male controls were included in our study. Third degree cases were more likely to have a non-Hispanic black or Asian/Pacific Islander mother, be delivered preterm, have a low birth weight, be small for gestational age, and be conceived with fertility treatments than second degree cases and controls. Associations with both second and third degree hypospadias were observed for maternal age, family history, parity, plurality, and hypertension during pregnancy. Risk estimates were generally higher for third degree hypospadias except for family history. Conclusions Most risk factors were associated with both or neither phenotype. Therefore, it is likely that the underlying mechanism is at least partly similar for both phenotypes. However, some associations were different between 2nd and 3rd degree hypospadias, and went in opposite directions for second and third degree hypospadias for Asian/Pacific Islander mothers. Effect estimates for subtypes of hypospadias may be over- or underestimated in studies without stratification by phenotype. PMID:25181604

  3. 3rd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of pancreatic cancer.

    Science.gov (United States)

    Lutz, Manfred P; Zalcberg, John R; Ducreux, Michel; Aust, Daniela; Bruno, Marco J; Büchler, Markus W; Delpero, Jean-Robert; Gloor, Beat; Glynne-Jones, Rob; Hartwig, Werner; Huguet, Florence; Laurent-Puig, Pierre; Lordick, Florian; Maisonneuve, Patrick; Mayerle, Julia; Martignoni, Marc; Neoptolemos, John; Rhim, Andrew D; Schmied, Bruno M; Seufferlein, Thomas; Werner, Jens; van Laethem, Jean-Luc; Otto, Florian

    2017-07-01

    The primary treatment of pancreatic cancer was the topic of the 3rd St. Gallen Conference 2016. A multidisciplinary panel reviewed the current evidence and discussed controversial issues in a moderated consensus session. Here we report on the key expert recommendations. It was generally accepted that radical surgical resection followed by adjuvant chemotherapy offers the only evidence-based treatment with a chance for cure. Initial staging should classify localised tumours as resectable or unresectable (i.e. locally advanced pancreatic cancer) although there remains a large grey-zone of potentially resectable disease between these two categories which has recently been named as borderline resectable, a concept which was generally accepted by the panel members. However, the definition of these borderline-resectable (BR) tumours varies between classifications due to their focus on either (i) technical hurdles (e.g. the feasibility of vascular resection) or (ii) oncological outcome (e.g. predicting the risk of a R1 resection and/or occult metastases). The resulting expert discussion focussed on imaging standards as well as the value of pretherapeutic laparoscopy. Indications for biliary drainage were seen especially before neoadjuvant therapy. Following standard resection, the panel unanimously voted for the use of adjuvant chemotherapy after R0 resection and considered it as a reasonable standard of care after R1 resection, even though the optimal pathologic evaluation and the definition of R0/R1 was the issue of an ongoing debate. The general concept of BR tumours was considered as a good basis to select patients for preoperative therapy, albeit its current impact on the therapeutic strategy was far less clear. Main focus of the conference was to discuss the limits of surgical resection and to identify ways to standardise procedures and to improve curative outcome, including adjuvant and perioperative treatment. Copyright © 2017 The Authors. Published by Elsevier

  4. Differences between 2nd and 3rd generation seric parathormone determination methods on mortality in haemodialysis patients.

    Science.gov (United States)

    Rodríguez-Osorio, Laura; de la Piedra, Concepción; Rubert, Mercedes; Martín-Fernández, Marta; González Casaus, María Luisa; Gracia-Iguacel, Carolina; Egido, Jesús; Villa-Bellosta, Ricardo; González Parra, Emilio

    Parathormone plays a key role in controlling mineral metabolism. PTH is considered a uremic toxin causing cardiovascular damage and cardiovascular mortality in dialysis patients. There are two different assays to measure PTH called 2nd generation or intact PTH (iPTH) and 3rd generation or bioPTH (PTHbio). To evaluate the differences in mortality of dialysis patients between both assays to measure PTH, as well as the possible prognostic role of the PTHbio/iPTH ratio. 145 haemodialysis patients were included with 2-year monitoring including baseline laboratory test and annually thereafter. 21 patients died in the first year and 28 in the second. No correlation was found between PTH, PTHbio and PTHbio/iPTH ratio with mortality. Both PTH have a perfect correlation between them and correlate similarly with other molecules of the mineral metabolism. The extreme baseline values of PTH are those of higher mortality. In survival by iPTH intervals (according to guidelines and COSMOS study), a J curve is observed. When iPTH increases, the ratio decreases, possibly when increasing fragments no. 1-84. There is no greater prognostic approximation on mortality with PTHbio than PTHi. There was also no difference in mortality when progression ratio PTHbio/PTHi was analysed. We didn't find any advantages to using bioPTH vs. PTHi as a marker of mortality. BioPTH limits of normality must be reevaluated because its relationship with iPTH is not consistent. Not knowing these limits affects its prognostic value. Copyright © 2017 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

  5. Report of the 3rd Havemeyer workshop on allergic diseases of the Horse, Hólar, Iceland, June 2007.

    Science.gov (United States)

    Marti, E; Gerber, V; Wilson, A D; Lavoie, J P; Horohov, D; Crameri, R; Lunn, D P; Antczak, D; Björnsdóttir, S; Björnsdóttir, T S; Cunningham, F; Dérer, M; Frey, R; Hamza, E; Horin, P; Heimann, M; Kolm-Stark, G; Olafsdóttir, G; Ramery, E; Russell, C; Schaffartzik, A; Svansson, V; Torsteinsdóttir, S; Wagner, B

    2008-12-15

    Allergic diseases occur in most mammals, although some species such as humans, dogs and horses seem to be more prone to develop allergies than others. In horses, insect bite hypersensitivity (IBH), an allergic dermatitis caused by bites of midges, and recurrent airway obstruction (RAO), a hyperreactivity to stable born dust and allergens, are the two most prevalent allergic diseases. Allergic diseases involve the interaction of three major factors: (i) genetic constitution, (ii) exposure to allergens, and (iii) a dysregulation of the immune response determined by (i) and (ii). However, other environmental factors such as infectious diseases, contact with endotoxin and degree of infestation with endoparasites have been shown to influence the prevalence of allergic diseases in humans. How these factors may impact upon allergic disease in the horse is unknown at this time. The 3rd workshop on Allergic Diseases of the Horse, with major sponsorship from the Havemeyer Foundation, was held in Hólar, Iceland, in June 2007 and focussed on immunological and genetic aspects of IBH and RAO. This particular venue was chosen because of the prevalence of IBH in exported Icelandic horses. The incidence of IBH is significantly different between Icelandic horses born in Europe or North America and those born in Iceland and exported as adults. Although the genetic factors and allergens are the same, exported adult horses show a greater incidence of IBH. This suggests that environmental or epigenetic factors may contribute to this response. This report summarizes the present state of knowledge and summarizes important issues discussed at the workshop.

  6. Electrocradiographic Qrs Axis, Q Wave and T-wave Changes in 2nd and 3rd Trimester of Normal Pregnancy.

    Science.gov (United States)

    M, Sunitha; S, Chandrasekharappa; Brid, S V

    2014-09-01

    Pregnancy although a physiological phenomena affects all the functions of the maternal body and brings about remarkable changes in the cardiovascular system. The cardiovascular changes and many of the physiological adaptations of normal pregnancy alter the physical findings thus, sometimes misleading the diagnosis of heart disease. Pregnancy also brings about various changes in the electrocardiogram, further confusing with that of heart disease. This study is undertaken to highlight the effect of normal pregnancy on the QRS axis, Q wave and T-wave of the Electrocardiogram and thereby helps us to distinguish it from that of pathological changes. To study the effect of normal pregnancy on the QRS axis, Q wave and T-wave in the electrocardiogram and to compare with that of normal non pregnant women. Fifty normal pregnant women in 2nd and 3rd trimester each between 20- 35 y of age and 50 normal non pregnant women of the same age group were selected for the study. A 12 lead ECG was recorded by using ECG machine with special emphasis on QRS axis, Q wave and T-wave changes and all the parameters were analysed. The ECG changes observed in our study include, deviation of QRS axis towards left as pregnancy advanced, significant increased incidence of occurrence of prominent Q waves in lead II, III and avF in pregnant group (p < 0.05 ) and, T-wave abnormalities like flat and inverted T-waves in lead III, V1 - V3 were more frequent in pregnant group ( p<0.05 ) than in non pregnant group. Normal pregnancy brings about various changes in ECG. These changes during pregnancy should be interpretated with caution by the physicians. It is necessary to understand the normal physiological changes which in turn help us in better management of those with cardiac disease.

  7. Moving from information and collaboration to action: report from the 3rd International Dog Health Workshop, Paris in April 2017.

    Science.gov (United States)

    O'Neill, Dan G; Keijser, Sylvia F A; Hedhammar, Åke; Kisko, Caroline; Leroy, Gregoire; Llewellyn-Zaidi, Aimée; Malm, Sofia; Olson, Patricia N; Packer, Rowena M A; Rousselot, Jean Francois; Seath, Ian J; Stull, Jason W; Bonnett, Brenda N

    2017-01-01

    Breed-related health problems in dogs have received increased focus over the last decade. Responsibility for causing and/or solving these problems has been variously directed towards dog breeders and kennel clubs, the veterinary profession, welfare scientists, owners, regulators, insurance companies and the media. In reality, all these stakeholders are likely to share some responsibility and optimal progress on resolving these challenges requires all key stakeholders to work together. The International Partnership for Dogs (IPFD), together with an alternating host organization, holds biennial meetings called the International Dog Health Workshops (IDHW). The Société Centrale Canine (French Kennel Club) hosted the 3rd IDHW, in Paris, in April, 2017. These meetings bring together a wide range of stakeholders in dog health, science and welfare to improve international sharing of information and resources, to provide a forum for ongoing collaboration, and to identify specific needs and actions to improve health, well-being and welfare in dogs. The workshop included 140 participants from 23 countries and was structured around six important issues facing those who work to improve dog health. These included individualized breed-specific strategies for health and breeding, extreme conformations, education and communication in relation to antimicrobial resistance, behavior and welfare, genetic testing and population-based evidence. A number of exciting actions were agreed during the meeting. These included setting up working groups to create tools to help breed clubs accelerate the implementation of breed-health strategies, review aspects of extreme conformation and share useful information on behavior. The meeting also heralded the development of an online resource of relevant information describing quality measures for DNA testing. A demand for more and better data and evidence was a recurring message stressed across all themes. The meeting confirmed the benefits from

  8. PREFACE: 3rd International Conference on Science & Engineering in Mathematics, Chemistry and Physics 2015 (ScieTech 2015)

    Science.gov (United States)

    Gaol, F. L.

    2015-06-01

    The 3rd International Conference on Science & Engineering in Mathematics, Chemistry and Physics 2015 (ScieTech 2015), was held at The Westin Resort Nusa Dua, Bali on 31 January - 1 February 2015. The ScieTech 2015 conference is aimed to bring together researchers, engineers and scientists from around the world. ScieTech 2015 is placed on promoting interaction between the theoretical, experimental, and applied communities, so that a high level exchange is achieved in new and emerging areas within mathematics, chemistry and physics. As we already know that science and technology have brought tremendous benefits for human civilization. People are becoming healthier, wealthier, better educated, more peaceful, increasingly connected, and living longer. Of course, science and technology provide many answers to global challenges, but we will face more complex problems in the next decade due to increasing world population, limitation of energy, and climate change. Therefore, researchers should be more active in conducting research that enables collaboration between one and the others. Interdisciplinary cooperation is absolutely necessary in order to create a smart system for solving the global problems. We need a global and general long-term view of the future with long-range goals for solving complex problems in next decade. Therefore the conference was held to be a forum for researchers from different disciplines to start collaborating and conducting research that provides a solution to the global issues. The theme of ScieTech 2015 was ''The interdisciplinary Application between Mathematics, Chemistry and Physics to enhance the Quality of Life''. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting conference program as well as the invited and plenary speakers. This year, we received 197 papers and after rigorous review, 59 papers were accepted. The participants came from 19

  9. Medical students’ skills in image interpretation before and after training: A comparison between 3rd-year and 6th-year students from two different medical curricula

    Energy Technology Data Exchange (ETDEWEB)

    Sendra-Portero, Francisco, E-mail: sendra@uma.es [Departamento de Radiología y Medicina Física, Facultad de Medicina, Universidad de Málaga, Boulevar Louis Pasteur, 32, 29071 Málaga (Spain); Torales-Chaparro, Oscar E., E-mail: oetjft@terra.es [Departamento de Radiología y Medicina Física, Facultad de Medicina, Universidad de Málaga, Boulevar Louis Pasteur, 32, 29071 Málaga (Spain); Ruiz-Gómez, Miguel J., E-mail: mjrg@uma.es [Departamento de Radiología y Medicina Física, Facultad de Medicina, Universidad de Málaga, Boulevar Louis Pasteur, 32, 29071 Málaga (Spain)

    2012-12-15

    The purpose of this study was to assess student's performance in the interpretation of images before and after training in radiology, by comparing two groups, 6th-year and 3rd-year students, from two different medical curricula. Students participated in an anonymous evaluation consisting of the interpretation of 12 radiological images accompanied with the salient history and clinical data by answering 60 open-ended questions about technique, anatomy, semiology, and clinics. The number of correct, incorrect and blank responses of each group was used to compare pre- and post-training results. Unpaired two-sample t-test was used to evaluate differences between groups. A significant increase in correct responses was found in both groups after training. The comparison between both groups did not show differences for incorrect answers of the whole test and correct answers about anatomy in the pre-training evaluation. The percentage of correct answers to the median question improved from 15.5% to 53.3% for 6th-year students and from 8.3% to 41.1% for 3rd-year students. The post-training evaluation showed a significant increase of correct answers of 6th-year students with respect to 3rd-year students (mean ± standard deviation 53.6 ± 31.3% and 38.7 ± 29.9% respectively), mainly due to differences in technical and clinical questions. This study provides objective and quantitative evidence of pre- and post-training student skills in image interpretation. The similarities found in the previous level of knowledge and skills of both groups emphasizes the suitable change of the first-time training in radiology, from the 6th to the 3rd year course in medical curricula.

  10. The construction of the CMS electromagnetic calorimeter: delivery of the 3rd and 4th endcap "Dees" and Ring Flanges to CERN

    CERN Multimedia

    2006-01-01

    Delivery of the 3rd and 4th Dees and Ring Flanges of the CMS-ECAL endcaps to CERN. The pictures show also an endcap crystal with its VPT (Vacuum PhotoTriode), the aluminium blackplates of the endcap Dees and four mock supercrystals (5x5 crystals) attached in their position on the backplate, along with 138 positional spacers. Finally, endcap assembly in the CMS construction hall in Cessy (neighbouring France) is also shown.

  11. Proceedings of the 3rd Biennial Conference of the Society for Implementation Research Collaboration (SIRC) 2015: advancing efficient methodologies through community partnerships and team science

    OpenAIRE

    Kerns, Suzanne; Puspitasari, Ajeng; Hendricks, Karin; Pierson, Andria; Fizur, Phil; Comtois, Katherine A.; Green, Amy E.; Trott, Elise M.; Willging, Cathleen E.; Fernandez, Maria E.; Woolf, Nicholas H.; Liang, Shuting Lily; Heredia, Natalia I.; Kegler, Michelle; Risendal, Betsy

    2016-01-01

    Table of contents Introduction to the 3rd Biennial Conference of the Society for Implementation Research Collaboration: advancing efficient methodologies through team science and community partnerships Cara Lewis, Doyanne Darnell, Suzanne Kerns, Maria Monroe-DeVita, Sara J. Landes, Aaron R. Lyon, Cameo Stanick, Shannon Dorsey, Jill Locke, Brigid Marriott, Ajeng Puspitasari, Caitlin Dorsey, Karin Hendricks, Andria Pierson, Phil Fizur, Katherine A. Comtois A1: A behavioral economic perspective ...

  12. Food Micro 2010, 22th International ICFMH Symposium, “ Microbial Behaviour in the Food Chain ” 30th August – 3rd September 2010, Copenhagen, Denmark

    DEFF Research Database (Denmark)

    2012-01-01

    This Special Issue of International Journal of Food Microbiology contains a selection of papers presented at Food Micro 2010, the 22th Symposium of the International Committee on Food Microbiology and Hygiene (ICFMH). Food Micro 2010 was held on 30th August to 3rd September 2010 in Copenhagen......, Denmark and organized in collaboration between the Danish Centre for Advanced Food Studies (LMC) and Lund University in Sweden....

  13. Basic Wiring. Third Edition. Teacher Edition [and] Student Edition.

    Science.gov (United States)

    Kaltwasser, Stan; Flowers, Gary; Blasingame, Don; Batson, Larry; Ipock, Dan; Carroll, Charles; Friesen, Wade; Fleming, Glenn

    This publication contains both a teacher edition and a student edition of materials for a foundation course in an electrical wiring program. The course introduces basic concepts and skills that are prerequisites to residential wiring and commercial and industrial wiring courses. The contents of the materials are tied to measurable and observable…

  14. Diesel Technology: Introduction. Teacher Edition [and] Student Edition. Second Edition.

    Science.gov (United States)

    Joerschke, John D.; Eichhorn, Lane

    This complete teacher edition of a diesel technology course consists of introductory pages, teacher pages, and the student edition. The introductory pages provide these tools: training and competency profile; National Automotive Technicians Education Foundation Crosswalk; instructional/task analysis; basic skills icons and classifications; basic…

  15. EPA Method 8321B (SW-846): Solvent-Extractable Nonvolatile Compounds by High Performance Liquid Chromatography-Thermospray-Mass Spectrometry (HPLC-TS-MS) or Ultraviolet (UV) Detection

    Science.gov (United States)

    Method 8321B describes procedures for preparation and analysis of solid, aqueous liquid, drinking water and wipe samples using high performance liquid chromatography and mass spectrometry for extractable non-volatile compounds.

  16. SW-846 Test Method 3200: Mercury Species Fractionation and Quantification by Microwave Assisted Extraction, Selective Solvent Extraction and/or Solid Phase Extraction

    Science.gov (United States)

    a sequential extraction and separation procedure that maybe used in conjunction with a determinative method to differentiate mercury species that arepresent in soils and sediments. provides information on both total mercury andvarious mercury species.

  17. Wikipedia editing dynamics

    Science.gov (United States)

    Gandica, Y.; Carvalho, J.; Sampaio dos Aidos, F.

    2015-01-01

    A model for the probabilistic function followed in editing Wikipedia is presented and compared with simulations and real data. It is argued that the probability of editing is proportional to the editor's number of previous edits (preferential attachment), to the editor's fitness, and to an aging factor. Using these simple ingredients, it is possible to reproduce the results obtained for Wikipedia editing dynamics for a collection of single pages as well as the averaged results. Using a stochastic process framework, a recursive equation was obtained for the average of the number of edits per editor that seems to describe the editing behavior in Wikipedia.

  18. The 3rd CARISMA international conference on medium and high temperature proton exchange membrane fuel cells: Three approaches to better platinum catalysts at biannual conference

    DEFF Research Database (Denmark)

    Jensen, Jens Oluf; Cleemann, Lars Nilausen; Li, Qingfeng

    2013-01-01

    The 3rd CARISMA International Conference was held at the Axelborg venue in Copenhagen, Denmark, from September 3-5, 2012. The CARISMA conference series was specifically devoted to challenges in the development and testing of fuel cell materials and membrane electrode assemblies (MEAs) for proton...... exchange membrane fuel cells (PEMFCs) to be operated at intermediate and high temperatures. The conference series was initiated by the European CARISMA Coordination Action for Research on Intermediate and High Temperature Specialized Membrane Electrode Assemblies. The 2012 event in Copenhagen had around...

  19. Sarmatian Attributes in Archaeological Complexes of Catacombs Burials in Arys Culture of Southern Kazakhstan (1st Century B.C. - 3rd Century A.D.)

    OpenAIRE

    Podushkin Aleksandr Nikolaevich

    2015-01-01

    The publication is devoted to archaeological research of monuments of the catacomb of Arys culture of Southern Kazakhstan (1st Century B.C. - 3rd Century A.D.). Now scientists have a complete understanding of the range and typology, periodization and chronology of monuments of this culture. There are three stages: Karaultobe (4th century B.C. - 1st century A.D.); Karatobe (1st Century B.C. - 4th century A.D.); Altintobe (4th-6th centuries A.D.). These stages are characterized by specific ...

  20. Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors.

    Science.gov (United States)

    Wright, John M; Vered, Marilena

    2017-03-01

    The 4th edition of the World Health Organization's Classification of Head and Neck Tumours was published in January of 2017. This article provides a summary of the changes to Chapter 4 Tumours of the oral cavity and mobile tongue and Chapter 8 Odontogenic and maxillofacial bone tumours. Odontogenic cysts which were eliminated from the 3rd 2005 edition were included in the 4th edition as well as other unique allied conditons of the jaws. Many new tumors published since 2005 have been included in the 2017 classification.

  1. Multiplex editing system

    DEFF Research Database (Denmark)

    2015-01-01

    The present invention relates to a multiplex editing system. The system allows multiple editing of nucleic acid sequences such as genomic sequences, such as knockins of genes of interest in a genome, knockouts of genomic sequences and/or allele replacement. Also provided herein are a method...... for editing nucleic acids and a cell comprising a stably integrated endonuclease....

  2. Orthotics, prosthesis and mobility aids (OPM dispensation in the Regional Health Department of the 3RD Region of Sao Paulo State

    Directory of Open Access Journals (Sweden)

    Camila Caminha Caro

    2014-12-01

    Full Text Available Objective: To identify the process of dispensation of orthotics, prostheses and mobility aids (OPM by the Unified Health System (SUS in the Regional Health Department of the 3rd Region (DRSIII of Sao Paulo state; perform a mapping of the existing physical rehabilitation services in that region; and subsequently correlate the data with applicable laws. Methodology: This is an exploratory cross-sectional qualitative study whose subjects were the main professionals involved in the process of OPM dispensation, or responsible for their acquisition flow in the cities of that region. Data collection was carried out through a semi-structured questionnaire, developed by the researchers themselves, composed of questions aiming to identify the physical rehabilitation centers in the towns, the staff members involved, the provision of assistive technology through SUS, delivery time and existence of waiting lists. Results and discussion: The data were statistically measured, categorized, described and correlated with the current legislation aimed to guarantee access to assistive technology. We observed that the practice around this resource in the 3rd region concentrates in a single care center, causing long waits and poor efficiency of the services provided, in addition to maintaining a paternalistic aspect. Conclusion: This study provides evidence that, although the right to access to assistive technology is legally guaranteed, there are still many difficulties and challenges around this practice.

  3. 4 August 2011 - Austrian Head of Protocol, Directorate General III, Federal Ministry of Science and Research I. Friedrich (3rd from left) in the LHC superconducting magnet test hall with M. Benedkit, C. Wulz and C. Fabjan.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    4 August 2011 - Austrian Head of Protocol, Directorate General III, Federal Ministry of Science and Research I. Friedrich (3rd from left) in the LHC superconducting magnet test hall with M. Benedkit, C. Wulz and C. Fabjan.

  4. Coronary CT angiography in obese patients using 3(rd) generation dual-source CT: effect of body mass index on image quality.

    Science.gov (United States)

    Mangold, Stefanie; Wichmann, Julian L; Schoepf, U Joseph; Litwin, Sheldon E; Canstein, Christian; Varga-Szemes, Akos; Muscogiuri, Giuseppe; Fuller, Stephen R; Stubenrauch, Andrew C; Nikolaou, Konstantin; De Cecco, Carlo N

    2016-09-01

    To evaluate the image quality of coronary CT angiography (CCTA) in obese patients using a 3(rd) generation, dual-source CT scanner. We retrospectively evaluated 102 overweight and obese patients who had undergone CCTA. Studies were performed with 3(rd) generation dual-source CT, prospectively ECG-triggered acquisition at 120 kV, and automated tube current modulation. Advanced modeled iterative reconstruction was used. Patients were divided into three BMI groups: 1)25-29.9 kg/m(2); 2)30-39.9 kg/m(2); 3) ≥ 40 kg/m(2). Vascular attenuation in the coronary arteries was measured. Contrast-to-noise ratio (CNR) was calculated. Image quality was subjectively evaluated using five-point scales. Image quality was considered diagnostic in 97.6 % of examinations. CNR was consistently adequate in all groups but decreased for groups 2 and 3 in comparison to group 1 as well as for group 3 compared to group 2 (p = 0.001, respectively). Subjective image quality was significantly higher in group 1 compared to group 3 (attenuation proximal: 4.8 ± 0.4 vs. 4.4 ± 0.6, p = 0.011; attenuation distal: 4.5 ± 0.7 vs. 4.0 ± 0.8, p = 0.019; noise: 4.7 ± 0.6 vs. 3.8 ± 0.7, p rd) generation DSCT at 120 kV. • Diagnostic CCTA can be routinely performed in obese patients with 3 (rd) generation DSCT. • 120-kV tube voltage allows diagnostic image quality in patients with BMI > 40 kg/m (2) . • 80-ml contrast medium can be administered without significant decline in vascular attenuation.

  5. Final report for the 3rd Ex-Vessel Neutron Dosimetry Installations and Evaluations for Kori Unit 1 Reactor Pressure Vessel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byoung Chul; Yoo, Choon Sung; Lee, Sam Lai (and others)

    2008-03-15

    This report describes a neutron fluence assessment performed for the Kori Unit 1 pressure vessel belt line region based on the guidance specified in Regulatory Guide 1.190. In this assessment, maximum fast neutron exposures expressed in terms of fast neutron fluence (E>1 MeV) and iron atom displacements (dpa) were established for the belt line region of the pressure vessel. After Cycle 23 of reactor operation, 3rd Ex-Vessel Neutron Dosimetry Program was instituted at Kori Unit 1 to provide continuous monitoring of the belt line region of the reactor vessel. The use of the Ex-Vessel Neutron Dosimetry Program coupled with available surveillance capsule measurements provides a plant specific data base that enables the evaluation of the vessel exposure and the uncertainty associated with that exposure over the service life of the unit. Ex-Vessel Neutron Dosimetry has been evaluated at the conclusion of Cycle 24.

  6. An estimate of the minting method of three silver coins of the 3rd century B.C. through their microstructural study

    Energy Technology Data Exchange (ETDEWEB)

    Pistofidis, N.; Vourlias, G. [Department of Physics, Aristotle University of Thessaloniki, Thessaloniki (Greece); Dilo, T. [Department of Physics, FNSc, University of Tirana, Tirana (Albania); Civici, N. [Department of Spectroscopy, Institute of Nuclear Physics, Tirana (Albania); Gjongecaj, Sh. [Department of Antiquity, Institute of Archaeology, Tirana (Albania); Skolianos, S. [Physical Metallurgy Laboratory, Department of mechanical Engineering, Aristotle University of Thessaloniki, 54124, Thessaloniki (Greece); Polychroniadis, E.K., E-mail: polychr@auth.g [Department of Physics, Aristotle University of Thessaloniki, Thessaloniki (Greece)

    2010-05-01

    The microstructure of three silver coins of the 3rd century B.C. from the Illyrian King Monounios and the ancient Greek cities of Dyrrachion and Corcyra, belonging to the Kreshpan hoard, was determined with X-ray diffraction and transmission electron microscopy in order to investigate their minting method. It is deduced that the coins are characterized by a large number of structural defects, mainly dislocations, twins and microtwins, which in some cases were bent. These crystal defects are common in each of the coins examined. This information allowed the formulation of a possible minting method. Since twins in FCC metals are formed with thermal treatment, and mechanical twinning is rather improbable, it seems that the coins were initially hot-worked. Bent twins indicate that working continued during cooling. Especially for the Corcyra coin it was deduced that it was treated at higher temperature or its cooling rate was lower.

  7. Reflections: Surgical Education-the Times they are a-Changin': Lessons Learned from the 3rd MAYMET-ESO Joint Meeting.

    Science.gov (United States)

    Tarkowski, Radoslaw; Vetto, John T

    2015-09-01

    Technical skills are not sufficient for successful surgical care. Non-technical skills such as team work, decision-making in cancer treatment, communication with the patient, ethical challenges, situation awareness, and communication in the operating room are mandatory for favorable outcomes. Although formally taught in other high-demand disciplines, such skills were traditionally rarely discussed in surgical oncology. The 3rd MAYMET-ESO Joint Meeting "Professionalism for Breast Surgeons" held in Istanbul, Turkey, 5 October 2013 was dedicated to the development of non-technical skills in the everyday activity of breast surgeons. We briefly discuss information from this very interesting and inspiring educational event and how it relates to more recent changes in surgical oncology education.

  8. Cellars, stone wine and oil presses in the territory of Kelin (5th-3rd centuries BC: the case of la Alcantarilla ravine (Requena, Valencia

    Directory of Open Access Journals (Sweden)

    David Quixal Santos

    2016-11-01

    Full Text Available Archaeological evidences date the expansion of grape vineyards in the territory of the Iberian Iron Age city of Kelin from the 5th to 3rd centuries BC; although the origins are documented in the 7th BC. One of the singularities of this territory is the existence of outdoors stone structures for the production of wine and oil. All are located in a specific area of the territory (la Alcantarilla and Los Morenos ravines (Requena, Valencia, and are associated with archaeological materials that allow date them as Iberian. In this paper we approach the rural settlement pattern in la Alcantarilla ravine and we present in detail the archaeological sites of Rambla de la Alcantarilla and Solana de Cantos 2.

  9. Motivation in school physical education: practice reports to teachers to students of 3rd secondary education series of state network paulista

    Directory of Open Access Journals (Sweden)

    Paulo César Cedran

    2016-05-01

    Full Text Available In the current design of School Physical Education the figure of the teacher should represent the mediation between knoledge and the teaching-learning process. So, thinking about the importance of the role that Professional in motivating students to participate in physical education classes, this paper aims reporting these experiences in building a concepto f physical education to arouse student’s interest in knowing it and the habito f practicing it. In this sense, our goal is to investigate and compare with schools in Pitangueiras/SP and Jaboticabal/SP cities, the motivational level of students in 3rd grade of High School in Physical Education classes, from the official curriculum implemented by the Department of Education of the State of São Paulo (ESS/SP in 2008.

  10. Limbic system development underlies the emergence of classical fear conditioning during the 3rd and 4th weeks of life in the rat

    Science.gov (United States)

    Deal, Alex L.; Erickson, Kristen J.; Shiers, Stephanie I.; Burman, Michael A.

    2016-01-01

    Classical fear conditioning creates an association between an aversive stimulus and a neutral stimulus. Although the requisite neural circuitry is well understood in mature organisms, the development of these circuits is less well studied. The current experiments examine the ontogeny of fear conditioning and relate it to neuronal activation assessed through immediate early gene (IEG) expression in the amygdala, hippocampus, perirhinal cortex, and hypothalamus of periweanling rats. Rat pups were fear conditioned, or not, during the 3rd or 4th weeks of life. Neuronal activation was assessed by quantifying expression of FBJ osteosarcoma oncogene (FOS) using immunohistochemistry (IHC) in Experiment 1. Fos and early growth response gene-1 (EGR1) expression was assessed using qRT-PCR in Experiment 2. Behavioral data confirm that both auditory and contextual fear continue to emerge between PD 17 and 24. The IEG expression data are highly consistent with these behavioral results. IHC results demonstrate significantly more FOS protein expression in the basal amygdala of fear conditioned PD 23 subjects compared to control subjects, but no significant difference at PD 17. qRT-PCR results suggest specific activation of the amygdala only in older subjects during auditory fear expression. A similar effect of age and conditioning status was also observed in the perirhinal cortex during both contextual and auditory fear expression. Overall, the development of fear conditioning occurring between the 3rd and 4th weeks of life appears to be at least partly attributable to changes in activation of the amygdala and perirhinal cortex during fear conditioning or expression. PMID:26820587

  11. Sarmatian Attributes in Archaeological Complexes of Catacombs Burials in Arys Culture of Southern Kazakhstan (1st Century B.C. - 3rd Century A.D.

    Directory of Open Access Journals (Sweden)

    Podushkin Aleksandr Nikolaevich

    2015-12-01

    Full Text Available The publication is devoted to archaeological research of monuments of the catacomb of Arys culture of Southern Kazakhstan (1st Century B.C. - 3rd Century A.D.. Now scientists have a complete understanding of the range and typology, periodization and chronology of monuments of this culture. There are three stages: Karaultobe (4th century B.C. - 1st century A.D.; Karatobe (1st Century B.C. - 4th century A.D.; Altintobe (4th-6th centuries A.D.. These stages are characterized by specific clusters of signs in the form of artifacts. The author also carried out the ethnic attribution of the Arys culture in association with the ancient state Kangiuj. As a result of this work, the ethnicity of the state Kangiuj was revealed: in particular, late Saka’s, Sarmatian, Huns and Kangiuj ethnic components which are relevant to archaeological complexes, were identified. In the Arys monuments of culture the author discovered complexes of findings which associated with the Sarmatian world of Eurasia by their ethno-cultural parameters. They include typical for the Sarmatians list of ritual action and the funerary equipment, including weapons, bronze mirrors, ritual and religious objects, signs-tamgas, jewelry (including Egyptian faience, articles in “animal”, gold-turquoise and polychrome style. The characteristics of the burial complexes of catacombs of the Arys culture discussed in the publication and corresponding to chronological calculations and ethno-cultural interpretations, allow to speak about presence in the territory of South Kazakhstan of the Asian Sarmatians or any local branch of the Union of the Sarmatian tribes in the 1st century B.C. - 3rd century A.D.

  12. Knowledge and institutional requirements to promote land degradation neutrality in drylands - An analysis of the outcomes of the 3rd UNCCD scientific conference

    Science.gov (United States)

    Akhtar-Schuster, Mariam; Safriel, Uriel; Abraham, Elena; de Vente, Joris; Essahli, Wafa; Escadafal, Richard; Stringer, Lindsay

    2015-04-01

    Achieving land degradation neutrality (LDN) through sustainable land management (SLM) targets the maintenance or restoration of the productivity of land, and therefore has to include decision-makers, knowledge generators and knowledge holders at the different relevant geographic scales. In order to enhance the implementation of the Convention, the Conference of the Parties (COP) of the United Nations Convention to Combat Desertification therefore decided that each future session of its Committee on Science and Technology (CST) would be organized in a predominantly scientific and technical conference-style format. This contribution will outline the major outcomes of UNCCD's 3rd scientific conference that will be held in Cancún, Mexico, from 9 to 12 March 2015, on addressing desertification, land degradation and drought issues (DLDD) for poverty reduction and sustainable development. The conference follows an exceptional new round table conference format that will allow the various stakeholders to discuss scientific as well as the contribution of traditional knowledge and practices in combating land degradation. This format should provide two-way communication and enable deeper insight into the availability and contribution of all forms of knowledge for achieving LDN through the assessment of: • the vulnerability of lands to DLDD and climate change and the adaptive capacities of socio-ecosystems; • best examples of adapted, knowledge-based practices and technologies; • monitoring and assessment methods to evaluate the effectiveness of adaptation practices and technologies. The outcomes of UNCCD's 3rd scientific conference will serve as a basis for discussing: • contributions of science to diagnose the status of land; • research gaps that need to be addressed to achieve LDN for poverty reduction; • additional institutional requirements to optimally bridge knowledge generation, knowledge maintenance and knowledge implementation at the science

  13. Comparison of 4th-Generation HIV Antigen/Antibody Combination Assay With 3rd-Generation HIV Antibody Assays for the Occurrence of False-Positive and False-Negative Results.

    Science.gov (United States)

    Muthukumar, Alagarraju; Alatoom, Adnan; Burns, Susan; Ashmore, Jerry; Kim, Anne; Emerson, Brian; Bannister, Edward; Ansari, M Qasim

    2015-01-01

    To assess the false-positive and false-negative rates of a 4th-generation human immunodeficiency virus (HIV) assay, the Abbott ARCHITECT, vs 2 HIV 3rd-generation assays, the Siemens Centaur and the Ortho-Clinical Diagnostics Vitros. We examined 123 patient specimens. In the first phase of the study, we compared 99 specimens that had a positive screening result via the 3rd-generation Vitros assay (10 positive, 82 negative, and 7 indeterminate via confirmatory immunofluorescent assay [IFA]/Western blot [WB] testing). In the second phase, we assessed 24 HIV-1 RNA-positive (positive result via the nuclear acid amplification test [NAAT] and negative/indeterminate results via the WB test) specimens harboring acute HIV infection. The 4th-generation ARCHITECT assay yielded fewer false-positive results (n = 2) than the 3rd-generation Centaur (n = 9; P = .02) and Vitros (n = 82; P positive case had a false-negative result via the Centaur assay. When specimens from the 24 patients with acute HIV-1 infection were tested, the ARCHITECT assay yielded fewer false-negative results (n = 5) than the Centaur (n = 10) (P = .13) and the other 3rd-generation tests (n = 16) (P = .002). This study indicates that the 4th-generation ARCHITECT HIV assay yields fewer false-positive and false-negative results than the 3rd-generation HIV assays we tested. Copyright© by the American Society for Clinical Pathology (ASCP).

  14. 3rd International EXAFS Conference

    CERN Document Server

    Hedman, Britt; Penner-Hahn, James

    1984-01-01

    This volume contains the Proceedings of the Third International EXAFS Conference, hosted by Stanford University and the Stanford Synchrotron Radiation Laboratory on July 16-20, 1984. The meeting, co-chaired by Professors Arthur Bienenstock and Keith Hodgson, was attended by over 200 scientists representing a wide range of scientific disciplines. The format of the meeting consisted of 51 invited presenta­ tions and four days of poster sessions. This Proceedings is a compilation of 139 contributions from both invited speakers and authors of contributed posters. The last ten years has seen the rapid maturation of x-ray absorption spectrosco­ pyas a scientific discipline. The vitality of the field is reflected in the diver­ sity of applications found in the Proceedings. Recent work continues to probe the limits of x-ray spectroscopy, with proven techniques being extended to, for examp­ le, very low or high energy studies, to very dilute systems, and to studies of surface structure. In fact, the title of the c...

  15. 3rd International Algebra Conference

    CERN Document Server

    Fong, Yuen; Zelmanov, Efim

    2003-01-01

    This volume contains one invited lecture which was presented by the 1994 Fields Medal­ ist Professor E. Zelmanov and twelve other papers which were presented at the Third International Conference on Algebra and Their Related Topics at Chang Jung Christian University, Tainan, Republic of China, during the period June 26-July 1, 200l. All papers in this volume have been refereed by an international referee board and we would like to express our deepest thanks to all the referees who were so helpful and punctual in submitting their reports. Thanks are also due to the Promotion and Research Center of National Science Council of Republic of China and the Chang Jung Christian University for their generous financial support of this conference. The spirit of this conference is a continuation of the last two International Tainan­ Moscow Algebra Workshop on Algebras and Their Related Topics which were held in the mid-90's of the last century. The purpose of this very conference was to give a clear picture of the rece...

  16. A Kinesthetic Learning Approach to Earth Science for 3rd and 4th Grade Students on the Pajarito Plateau, Los Alamos, NM

    Science.gov (United States)

    Wershow, H. N.; Green, M.; Stocker, A.; Staires, D.

    2010-12-01

    Current efforts towards Earth Science literacy in New Mexico are guided by the New Mexico Science Benchmarks [1]. We are geoscience professionals in Los Alamos, NM who believe there is an important role for non-traditional educators utilizing innovative teaching methods. We propose to further Earth Science literacy for local 3rd and 4th grade students using a kinesthetic learning approach, with the goal of fostering an interactive relationship between the students and their geologic environment. We will be working in partnership with the Pajarito Environmental Education Center (PEEC), which teaches the natural heritage of the Pajarito Plateau to 3rd and 4th grade students from the surrounding area, as well as the Family YMCA’s Adventure Programs Director. The Pajarito Plateau provides a remarkable geologic classroom because minimal structural features complicate the stratigraphy and dramatic volcanic and erosional processes are plainly on display and easily accessible. Our methodology consists of two approaches. First, we will build an interpretive display of the local geology at PEEC that will highlight prominent rock formations and geologic processes seen on a daily basis. It will include a simplified stratigraphic section with field specimens and a map linked to each specimen’s location to encourage further exploration. Second, we will develop and implement a kinesthetic curriculum for an exploratory field class. Active engagement with geologic phenomena will take place in many forms, such as a scavenger hunt for precipitated crystals in the vesicles of basalt flows and a search for progressively smaller rhyodacite clasts scattered along an actively eroding canyon. We believe students will be more receptive to origin explanations when they possess a piece of the story. Students will be provided with field books to make drawings of geologic features. This will encourage independent assessment of phenomena and introduce the skill of scientific observation. We

  17. Digital Video Editing

    Science.gov (United States)

    McConnell, Terry

    2004-01-01

    Monica Adams, head librarian at Robinson Secondary in Fairfax country, Virginia, states that librarians should have the technical knowledge to support projects related to digital video editing. The process of digital video editing and the cables, storage issues and the computer system with software is described.

  18. The genome editing revolution

    DEFF Research Database (Denmark)

    Stella, Stefano; Montoya, Guillermo

    2016-01-01

    -Cas system has become the main tool for genome editing in many laboratories. Currently the targeted genome editing technology has been used in many fields and may be a possible approach for human gene therapy. Furthermore, it can also be used to modifying the genomes of model organisms for studying human...

  19. Fatigue 󈨛. Papers presented at the International Conference on Fatigue and Fatigue Threshold (3rd) Held in Charlottesville, Virginia on June 28-July 3, 1987. Volume 3.

    Science.gov (United States)

    1987-10-15

    P.J. and Forre, B., Proc. Int. Conf. Fatigue Thresholds, Stockholm 1981, EMAS 1982, vol. 1, pp. 471-487. (4) Grovlen, M.K., Serge , T. and Bardal, E...34, Edited by R. C. Brandt, P. P. H. Hasselmann and F. F. Lange , Plenum Press, New York, U.S.A., 1978. (3) Sakaguchi, S., Sawaki, Y., Abe, Y. and Kawasaki

  20. Baseline Hepatitis B Virus DNA Level is a Promising Factor for Predicting the 3 (rd) Month Virological Response to Entecavir Therapy: A Study of Strict Defined Hepatitis B virus Induced Cirrhosis.

    Science.gov (United States)

    Xu, Yang; Wu, Xiao-Ning; Shi, Yi-Wen; Wei, Wei; Yang, Ai-Ting; Sun, Ya-Meng; Zhao, Wen-Shan; You, Hong

    2015-07-20

    Cirrhosis is a common complication of chronic hepatitis B. It remains unclear if viral and biochemical parameters at baseline affect virological response to entecavir and therefore warrant investigation. In the present study, we aimed to evaluate the efficacy of entecavir therapy by monitoring virological response at the end of the 3 rd month of treatment and try to figure out whether baseline factors could help predict it in a cohort of hepatitis B virus (HBV) compensated cirrhosis patients and to determine the cut-off value of a predicting parameter. A total of 91 nucleos(t)ide-naïve patients with HBV induced cirrhosis (compensatory stage) were enrolled in a prospective cohort. HBV DNA and alanine aminotransferase (ALT) were tested at baseline and monitored every 3-6 months after starting therapy. Of all 91 patients, the median follow-up time was 12 (9-24) months. Overall, 64 patients (70.3%) achieved virological response in the 3 rd month. Univariate analysis showed that the 3 rd month virological response can be predicted by baseline HBV DNA levels (P rd month (P = 0.001). Area under receiver operating characteristic curve for determining the 3 rd month virological response by baseline HBV DNA was 77.6% (95% CI: 66.7-85.2%), with a best cut-off value of 5.8 log 10 . Baseline HBV DNA, HBeAg negativity, and ALT were independent factors contributing to virological response at the 3 rd month. Further, multiple regression showed that HBV DNA level was the only parameter predicting full virological response as early as the 3 rd month, in this cirrhosis cohort.

  1. Evidence of human-induced morphodynamic changes along the Campania coastal areas (southern Italy) since the 3rd-4th cent. AD

    Science.gov (United States)

    Russo Ermolli, Elda; Romano, Paola; Liuzza, Viviana; Amato, Vincenzo; Ruello, Maria Rosaria; Di Donato, Valentino

    2014-05-01

    Campania has always offered suitable climatic and physiographic conditions for human settlements since prehistoric times. In particular, many Graeco-Roman towns developed along its coasts starting from the 7th-6th cent. BC. In the last decade, geoarchaelogical surveys have been carried out in the archaeological excavations of Neapolis, Paestum and Elea-Velia allowing the main steps of the landscape evolution around these towns to be defined in detail. The greek town of Neapolis rose in the late 6th cent. BC [1] on a terrace overlooking a low-relief rocky coast surrounded by volcanic hills. Port activities developed in a protected bay facing the town from the 4th-2nd cent. BC up to the 4th cent. AD, as testified by the discovery of structures and shipwrecks [2, 3, 4]. Starting from the 3rd cent. AD a spit bar formed at the bay entrance causing the progressive establishment of a lagoon which was gradually filled up by alluvial inputs and completely closed in the 5th cent. AD. During the same period, episodes of increased alluvial inputs were also recorded further west along the coast, where a narrow sandy beach formed at the cliff toe. The greek town of Poseidonia, renamed Paestum by the Romans, was founded in the 540 BC on a travertine terrace facing the sandy littoral of a prograding coastal plain [5]. In front of the main town door, a coastal lagoon developed thanks to the growth of a dune ridge and was probably used for harbor activities [5]. After this period the shoreline shifted seawards, another dune ridge formed and the back-ridge depression was filled with fluvial-marshy deposits, slowly drying up. Phases of travertine deposition, which characterized the SE sector of the plain all along the Holocene, were recorded in the northern and southern quarters of the town in historical times and were connected to the abandonment of the town in the early Medieval times. The greek colony of Elea-Velia was located on top of a siliciclastic promontory where the ruins of

  2. In vitro effects of three woody plant and sainfoin extracts on 3rd-stage larvae and adult worms of three gastrointestinal nematodes.

    Science.gov (United States)

    Paolini, V; Fouraste, I; Hoste, H

    2004-07-01

    Most studies on the effects of tanniferous plants on nematodes have examined forages but have neglected the woody plants. Therefore, in vitro effects of extracts from 3 woody plants (Rubus fructicosus, Quercus robur, Corylus avellana) have been tested on trichostrongyles and compared to sainfoin, a legume forage. Because some in vivo results indicated that the effects of tannins differed depending on the parasitic species and/or stages, the effects were measured on 3rd-stage larvae (L3) and adult worms of Teladorsagia circumcincta, Haemonchlus contortus and Trichostrongylus colubriformis. The effects of plant extracts varied according to the plant sources, the parasite species and stages. For the woody plants, significant inhibitory effects were obtained on both stages of abomasal species. Results for T. colubriformis were more variable. Effects of sainfoin extracts were significant on T. colubriformis and H. contortus L3, and on abomasal adult worms. In order to assess the implications of tannins, polyethylene glycol (PEG), an inhibitor of tannins, was added to hazel tree, oak and sainfoin extracts. Without PEG, significant inhibitory effects on L3 and adult worms were confirmed. After addition of PEG, the larval migration and motility of adult worms were restored in most cases. These results confirm variations in effects depending on factors related to plants or parasites and suggest that tannins are partly responsible for the effects.

  3. The impact of male burials on the construction of Corded Ware identity: Reconstructing networks of information in the 3rd millennium BC.

    Science.gov (United States)

    Bourgeois, Quentin; Kroon, Erik

    2017-01-01

    The emergence of Corded Ware Groups throughout Europe in the 3rd millennium BC is one of the most defining events in European history. From the Wolga to the Rhine communities start to speak Indo-European languages and bury their dead in an extremely similar fashion. Recent ancient DNA-analyses identify a massive migration from the Eurasian steppe as the prime cause for this event. However, there is a fundamental difference between expressing a Corded Ware identity-the sharing of world views and ideas-and having a specific DNA-profile. Therefore, we argue that investigating the exchange of cultural information on burial rites between these communities serves as a crucial complement to the exchange of biological information. By adopting a practice perspective to 1161 Corded Ware burials throughout north-western Europe, combined with similarity indexes and network representations, we demonstrate a high degree of information sharing on the burial ritual between different regions. Moreover, we show that male burials are much more international in character than female burials and as such can be considered as the vector along which cultural information and Corded Ware identity was transmitted. This finding highlights an underlying complex societal organization of Corded Ware burial rites in which gender roles had a significant impact on the composition and transmission of cultural information. Our findings corroborate recent studies that suggest the Corded Ware was a male focused society.

  4. Stable isotope and trace element studies on gladiators and contemporary Romans from Ephesus (Turkey, 2nd and 3rd Ct. AD--mplications for differences in diet.

    Directory of Open Access Journals (Sweden)

    Sandra Lösch

    Full Text Available The gladiator cemetery discovered in Ephesus (Turkey in 1993 dates to the 2nd and 3rd century AD. The aim of this study is to reconstruct diverse diet, social stratification, and migration of the inhabitants of Roman Ephesus and the distinct group of gladiators. Stable carbon, nitrogen, and sulphur isotope analysis were applied, and inorganic bone elements (strontium, calcium were determined. In total, 53 individuals, including 22 gladiators, were analysed. All individuals consumed C3 plants like wheat and barley as staple food. A few individuals show indication of consumption of C4 plants. The δ13C values of one female from the gladiator cemetery and one gladiator differ from all other individuals. Their δ34S values indicate that they probably migrated from another geographical region or consumed different foods. The δ15N values are relatively low in comparison to other sites from Roman times. A probable cause for the depletion of 15N in Ephesus could be the frequent consumption of legumes. The Sr/Ca-ratios of the gladiators were significantly higher than the values of the contemporary Roman inhabitants. Since the Sr/Ca-ratio reflects the main Ca-supplier in the diet, the elevated values of the gladiators might suggest a frequent use of a plant ash beverage, as mentioned in ancient texts.

  5. Stable Isotope and Trace Element Studies on Gladiators and Contemporary Romans from Ephesus (Turkey, 2nd and 3rd Ct. AD) - Implications for Differences in Diet

    Science.gov (United States)

    Lösch, Sandra; Moghaddam, Negahnaz; Grossschmidt, Karl; Risser, Daniele U.; Kanz, Fabian

    2014-01-01

    The gladiator cemetery discovered in Ephesus (Turkey) in 1993 dates to the 2nd and 3rd century AD. The aim of this study is to reconstruct diverse diet, social stratification, and migration of the inhabitants of Roman Ephesus and the distinct group of gladiators. Stable carbon, nitrogen, and sulphur isotope analysis were applied, and inorganic bone elements (strontium, calcium) were determined. In total, 53 individuals, including 22 gladiators, were analysed. All individuals consumed C3 plants like wheat and barley as staple food. A few individuals show indication of consumption of C4 plants. The δ13C values of one female from the gladiator cemetery and one gladiator differ from all other individuals. Their δ34S values indicate that they probably migrated from another geographical region or consumed different foods. The δ15N values are relatively low in comparison to other sites from Roman times. A probable cause for the depletion of 15N in Ephesus could be the frequent consumption of legumes. The Sr/Ca-ratios of the gladiators were significantly higher than the values of the contemporary Roman inhabitants. Since the Sr/Ca-ratio reflects the main Ca-supplier in the diet, the elevated values of the gladiators might suggest a frequent use of a plant ash beverage, as mentioned in ancient texts. PMID:25333366

  6. Phonological awareness and general performance in reading: What’s the relation? A study with 2nd and 3rd year fundamental school students

    Directory of Open Access Journals (Sweden)

    Ana Paula Couceiro Figueira

    2017-01-01

    Full Text Available The objective of this study was to test the content and concurrent validity of Prolec-R (FIGUEIRA; LOPES, n.d., investigation version, exploring the relations as a proof of phonological awareness (phoneme synthesis, SICOLE-R evaluation (FIGUEIRA; LOBO; LOPES; JIMÉNEZ, n.d., investigation version. The theoretical background comprises the evaluation of cognitive processes involved in reading (JIMENEZ’S and CUETOS’S perspectives, in which the two tests employed assume too evaluate such processes, and are considered concurrent procedures. Both are destined to children from 6 to 12 years old. The methodology used, for exploration and accessibility, a sample containing children from the 2nd and 3rd year of elementary school, from the public and education systems in Coimbra and Beira Interior Norte. The results revealed the existence of a positive and significant relation between the reading of words, reading of pseudo words, grammatical structures, punctuation marks and sentence comprehension (PROLEC-R and the phoneme synthesis (SICOLE-R.

  7. The impact of male burials on the construction of Corded Ware identity: Reconstructing networks of information in the 3rd millennium BC.

    Directory of Open Access Journals (Sweden)

    Quentin Bourgeois

    Full Text Available The emergence of Corded Ware Groups throughout Europe in the 3rd millennium BC is one of the most defining events in European history. From the Wolga to the Rhine communities start to speak Indo-European languages and bury their dead in an extremely similar fashion. Recent ancient DNA-analyses identify a massive migration from the Eurasian steppe as the prime cause for this event. However, there is a fundamental difference between expressing a Corded Ware identity-the sharing of world views and ideas-and having a specific DNA-profile. Therefore, we argue that investigating the exchange of cultural information on burial rites between these communities serves as a crucial complement to the exchange of biological information. By adopting a practice perspective to 1161 Corded Ware burials throughout north-western Europe, combined with similarity indexes and network representations, we demonstrate a high degree of information sharing on the burial ritual between different regions. Moreover, we show that male burials are much more international in character than female burials and as such can be considered as the vector along which cultural information and Corded Ware identity was transmitted. This finding highlights an underlying complex societal organization of Corded Ware burial rites in which gender roles had a significant impact on the composition and transmission of cultural information. Our findings corroborate recent studies that suggest the Corded Ware was a male focused society.

  8. Initial experience with temsirolimus in 2nd-, 3rd- and 4th-line therapy for metastatic renal cell cancer: good clinical response.

    Science.gov (United States)

    Kuru, Timur Hasan; Huber, Johannes; Hatiboglu, Gencay; Wagener, Nina; Pahernik, Sascha; Hadaschik, Boris; Hohenfellner, Markus

    2011-01-01

    To report our experience with temsirolimus in 2nd-, 3rd- and 4th-line therapy for patients with metastatic renal cell carcinoma (mRCC). In our prospectively maintained tumor registry, we identified 6 mRCC patients with temsirolimus in >1st-line systemic therapy. Patients were followed by weekly clinical and laboratory examination during admission of temsirolimus. Re-staging with chest CT and abdominal MRI was performed every 3 months. We observed excellent response rates. Progression-free survival (PFS) ranged from 6 to 40 months with a median of 15 months. Treatment was generally well tolerated. However, pneumonitis was observed in 4 of 6 patients. Drug-related pneumonitis led to severe dyspnea, with the result that treatment with temsirolimus had to be interrupted for a short period of time in 2 patients and discontinued in 1 patient. Temsirolimus proved to be a very good treatment option in 2nd- to 4th-line therapy with excellent response rates and manageable side effects. The incidence of pneumonitis must not be underestimated. Copyright © 2011 S. Karger AG, Basel.

  9. Assembly of insect hormone enthusiasts at Nasu Highland, Japan: Report of the 3rd International Insect Hormone (21st Ecdysone) Workshop.

    Science.gov (United States)

    Niwa, Ryusuke; Nishimura, Takashi

    2017-11-29

    The 3rd International Insect Hormone (21st Ecdysone) Workshop (IIHW2017) was held in July 2017 at Nasu Highland, Japan. In the 40 years of the workshop's history, this was the first to be held in an Asian country. A total of 109 insect hormone researchers from 18 countries (62 overseas and 47 domestic participants) attended IIHW2017. During the workshop, all participants stayed on-site at the venue's hotel; this was ideal for fostering communication between participants, in particular, interactions between principal investigators and young scientists. The workshop featured one keynote, 64 oral, and 35 poster presentations spanning molecular biology, cell biology, developmental biology, neurobiology, chemical biology, physiology, and ecology of insect hormones, including ecdysteroids, juvenile hormones, and a variety of neuropeptides. The workshop provided an ideal platform for discussing insect hormone biology using not only the typical genetic model insect, the fruit fly Drosophila, but also a diversity of interesting insects, such as the silkworm, the red flour beetle, the cricket, the dragonfly, the social ant, the bloodsucking tick, and so on. The participants succeeded in sharing the latest knowledge in a wide range of insect hormone research fields and in joining active and constructive scientific discussions. © 2017 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

  10. The Impact of Comprehensive Agrarian Reform Program (CARP on FarmerBeneficiaries in the 3rd Congressional District of Iloilo, Philippines

    Directory of Open Access Journals (Sweden)

    Ronaldo F. Frufonga

    2016-02-01

    Full Text Available The study aims to assess the impact of the comprehensive agrarian reform program on farmer beneficiaries in the 3rd Congressional District of the province of Iloilo for the year 2014. The Network design was used as research design to obtain and provide useful information in judging decision alternatives involve in the impact of Comprehensive Agrarian Reform Program to the farmerbeneficiaries. The participants were the 386 farmer beneficiaries. Data were gathered using surveychecklist form and analyzed through frequency counts, percentages, mean and t-test of dependent/correlated means. The researcher observed ethical considerations in conducting the study. The results show that the comprehensive agrarian reform program has a positive impact on the lives of the farmer beneficiaries. It has contributed to higher income and led to reduced poverty incidence before and after the program. The beneficiaries tend to be better off in terms of wellbeing compared to before the implementation of the program. They have better access to sanitary toilet facilities and potable water, and have a propensity to have higher educational attainment. Support services became essential in enhancing food security and building infrastructures that uphold food production, enhance trade, and increase income of the household beneficiaries living in the rural community. Further, the household farmer beneficiaries have a propensity to boost the chances to reduce poverty.

  11. Stable isotope and trace element studies on gladiators and contemporary Romans from Ephesus (Turkey, 2nd and 3rd Ct. AD)--mplications for differences in diet.

    Science.gov (United States)

    Lösch, Sandra; Moghaddam, Negahnaz; Grossschmidt, Karl; Risser, Daniele U; Kanz, Fabian

    2014-01-01

    The gladiator cemetery discovered in Ephesus (Turkey) in 1993 dates to the 2nd and 3rd century AD. The aim of this study is to reconstruct diverse diet, social stratification, and migration of the inhabitants of Roman Ephesus and the distinct group of gladiators. Stable carbon, nitrogen, and sulphur isotope analysis were applied, and inorganic bone elements (strontium, calcium) were determined. In total, 53 individuals, including 22 gladiators, were analysed. All individuals consumed C3 plants like wheat and barley as staple food. A few individuals show indication of consumption of C4 plants. The δ13C values of one female from the gladiator cemetery and one gladiator differ from all other individuals. Their δ34S values indicate that they probably migrated from another geographical region or consumed different foods. The δ15N values are relatively low in comparison to other sites from Roman times. A probable cause for the depletion of 15N in Ephesus could be the frequent consumption of legumes. The Sr/Ca-ratios of the gladiators were significantly higher than the values of the contemporary Roman inhabitants. Since the Sr/Ca-ratio reflects the main Ca-supplier in the diet, the elevated values of the gladiators might suggest a frequent use of a plant ash beverage, as mentioned in ancient texts.

  12. CRISPR Genome Editing

    Science.gov (United States)

    A research article about a technique for gene editing known as CRISPR-Cas9. The technique has made it much easier and faster for cancer researchers to study mutations and test new therapeutic targets.

  13. Image Quality of 3rd Generation Spiral Cranial Dual-Source CT in Combination with an Advanced Model Iterative Reconstruction Technique: A Prospective Intra-Individual Comparison Study to Standard Sequential Cranial CT Using Identical Radiation Dose.

    Directory of Open Access Journals (Sweden)

    Holger Wenz

    Full Text Available To prospectively intra-individually compare image quality of a 3rd generation Dual-Source-CT (DSCT spiral cranial CT (cCT to a sequential 4-slice Multi-Slice-CT (MSCT while maintaining identical intra-individual radiation dose levels.35 patients, who had a non-contrast enhanced sequential cCT examination on a 4-slice MDCT within the past 12 months, underwent a spiral cCT scan on a 3rd generation DSCT. CTDIvol identical to initial 4-slice MDCT was applied. Data was reconstructed using filtered backward projection (FBP and 3rd-generation iterative reconstruction (IR algorithm at 5 different IR strength levels. Two neuroradiologists independently evaluated subjective image quality using a 4-point Likert-scale and objective image quality was assessed in white matter and nucleus caudatus with signal-to-noise ratios (SNR being subsequently calculated.Subjective image quality of all spiral cCT datasets was rated significantly higher compared to the 4-slice MDCT sequential acquisitions (p<0.05. Mean SNR was significantly higher in all spiral compared to sequential cCT datasets with mean SNR improvement of 61.65% (p*Bonferroni0.05<0.0024. Subjective image quality improved with increasing IR levels.Combination of 3rd-generation DSCT spiral cCT with an advanced model IR technique significantly improves subjective and objective image quality compared to a standard sequential cCT acquisition acquired at identical dose levels.

  14. A «titulus pictus» with an imperial mention in «Carthago Nova» and some considerations concerning the urban dynamics of the city in the early 3rd century ad

    Directory of Open Access Journals (Sweden)

    José Miguel NOGUERA CELDRÁN

    2017-06-01

    Full Text Available The archaeological and epigraphic record in Carthago Nova suggests that the colony underwent a period of instability and urban retreat during the second half of the 2nd and the 3rd century ad. This was probably triggered by the slowing down of economic activity, a shrinking population and collapse of local institutions and the crisis of evergetism. The process caused a substantial transformation of urban landscapes and a reduction of the size of the inhabited areas; the interruption of the epigraphic habit, the abandonment, looting and reoccupation of public areas and buildings; the pulling down of domestic buildings; and the insufficient maintenance of the urban road network. This has led some specialists to suggest that the city lost importance, and even that it could have been totally abandoned during the second half of the 2nd and, especially, the 3rd century ad. The recent discovery of the substantial transformation of the Atrium Building (Insula i Molinete in the early 3rd century ad, and of a titulus pictus which mentions the consuls for the year, Heliogabalus and the prefect of the praetorium Adventus, which dates the final date for the refectio in 218 ad, resituates the debate around the retreat of the urban centre in the 2nd and 3rd centuries ad.

  15. Developing new levels of edit

    Energy Technology Data Exchange (ETDEWEB)

    Prono, J.K.

    1997-06-01

    Since 1985, Los Alamos National Laboratory (LANL) staff have had four levels of edit to choose from for technical reports. When a CQI survey showed that both authors and editors felt the levels were not meeting author needs, LANL set about revising them. The goals were to simplify the editing process, focus editing on improving technical clarity, and ensure value added in editing. This paper describes the revision process and product--three author-based levels of edit.

  16. On the Discovery of Eastern Hellenistic Initiatory Altar of the 3rd – 1st Centuries BC Depicting the Plot of Bull Sacrifice in the City of Stavropol

    Directory of Open Access Journals (Sweden)

    Prokopenko Yuriy A.

    2016-10-01

    Full Text Available The article is devoted to the semantic and chronological analysis of the images on the plate of white tuff discovered in the city of Stavropol. The central part of the relief is occupied with the image of table – an altar with hoisted bull head (in the background and the hanging part of bull skin (in the foreground. Between the protruding edges of the hanging skin and lower to the ground (between the legs of the altar an ancient Greek phrase carved in three lines. The composition is completed by flanking images of two figures in long robes depicted in profile, symmetrically turned to the head of the bull. The figure at the right is an image of a man with a long beard, the lower edge of which is bent forward (priest or king. The figure at the left is a female (queen. Both the man and the woman are holding ritual vessels in hands. The plot of bull sacrifice is typical for the cultural traditions of ancient Greece as well as for ancient eastern states. The fact of combining images and inscriptions peculiar of the Hellenistic culture and ancient Iranian mythology on the Stavropol altar should be associated with the religious policy pursued by the Pontic kings since the second half of the 3rd century BC till the Common Era. This policy was focused on the gradual replacement of local cults by Greek ones in the official pantheon. The reasons for the Asia Minor altar existence in the Stavropol Upland include: 1 the military expeditions of the Sarmatians to Asia Minor in 2nd – 1st centuries BC; 2 the establishment of political and economic ties by the North Caucasus population with the state of Seleucids in the 2nd century BC, with Parthia in the 2nd – 1st centuries BC, and especially with the kingdom of Pontus in the 1st century BC.

  17. A novel amperometric alcohol biosensor developed in a 3rd generation bioelectrode platform using peroxidase coupled ferrocene activated alcohol oxidase as biorecognition system.

    Science.gov (United States)

    Chinnadayyala, Somasekhar R; Kakoti, Ankana; Santhosh, Mallesh; Goswami, Pranab

    2014-05-15

    Alcohol oxidase (AOx) with a two-fold increase in efficiency (Kcat/Km) was achieved by physical entrapment of the activator ferrocene in the protein matrix through a simple microwave based partial unfolding technique and was used to develop a 3rd generation biosensor for improved detection of alcohol in liquid samples. The ferrocene molecules were stably entrapped in the AOx protein matrix in a molar ratio of ~3:1 through electrostatic interaction with the Trp residues involved in the functional activity of the enzyme as demonstrated by advanced analytical techniques. The sensor was fabricated by immobilizing ferrocene entrapped alcohol oxidase (FcAOx) and sol-gel chitosan film coated horseradish peroxidase (HRP) on a multi-walled carbon nanotube (MWCNT) modified glassy carbon electrode through layer-by-layer technique. The bioelectrode reactions involved the formation of H2O2 by FcAOx biocatalysis of substrate alcohol followed by HRP-catalyzed reduction of the liberated H2O2 through MWCNT supported direct electron transfer mechanism. The amperometric biosensor exhibited a linear response to alcohol in the range of 5.0 × 10(-6) to 30 × 10(-4)mol L(-1) with a detection limit of 2.3 × 10(-6) mol L(-1), and a sensitivity of 150 µA mM(-1) cm(-2). The biosensor response was steady for 28 successive measurements completed in a period of 5h and retained ~90% of the original response even after four weeks when stored at 4 °C. The biosensor was successfully applied for the determination of alcohol in commercial samples and its performance was validated by comparing with the data obtained by GC analyses of the samples. © 2013 Published by Elsevier B.V.

  18. STUDY OF THYROID PROFILE BY USING ULTRA SENSITIVE 3 rd GENERATION THYROID ASSAY IN TYPE 2 DIABETES MELLITUS PATIENTS IN A TERTIARY CARE CENTER

    Directory of Open Access Journals (Sweden)

    Rahul Ladda

    2017-01-01

    Full Text Available BACKGROUND Diabetes mellitus is a common endocrine disorder which is defined as a group of metabolic diseases characterized by hyperglycaemia resulting from defects in insulin secretion, insulin action, or both. Recently few studies have shown that Thyroid dysfunction especially hypothyroidism is found in patients with Type 2 Diabetes Mellitus but the mechanism for this is largely unknown. Unrecognized thyroid dysfunction can impair metabolic control in diabetes and may even exaggerate cardiovascular risk. Prompt detection and treatment may reduce risk derangement of cellular metabolism in diabetes mellitus and help achieving metabolic control in diabetes. AIMS AND OBJECTIVES OF THE STUDY To find the prevalence rate of thyroid disorders in type 2 diabetes mellitus by using 3 rd generation thyroid assay and distribution of thyroid disorders in patients with Type 2 diabetes mellitus MATERIALS AND METHODS 150 patients diagnosed with type 2 diabetes mellitus or newly detected Type 2 diabetes mellitus without thyroid disorders attending outpatient departments and admitted to General medicine wards of Basaveshwar teaching and general hospital were included in this study. RESULTS Of the 150 patients with Diabetes 88 patients (58.66% were male and 62 patients (41.33% were male. The mean age in diabetic group 56.48±11.64 years. 84 patients (54% in Diabetic group had hypertension and 25 patients (16.7% diabetic group had coronary artery disease 43 patients (28.66% had abnormal thyroid profile in diabetic group of which 23 patients (53.5% had subclinical hypothyroidism and 16 patients (37.3 % had overt hypothyroidism 2 (4.6 % patients had subclinical hyperthyroidism and 2 (4.6% had overt hyperthyroidism. CONCLUSION The prevalence (28.8% of thyroid dysfunction was common in type 2 diabetes mellitus patients. Our study shows significant co relation between abnormal thyroid profile and glycaemic control, dyslipidaemia and duration of diabetes.

  19. Participation in EU SARNET2 project for an enhancement of severe accident evaluation capability in domestic NPPs (3rd year R and D activities)

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Kwangil; Hong, S. W.; Kim, S. B.; Song, Y. M.; Kim, H. Y.; Park, R. J.; Park, J. H.; Park, S. Y.

    2012-07-15

    The following results were obtained from the 3rd year SARNET2 research activities. WP4-2: Establishment of the ASTEC code application framework to the domestic NPPs by analyzing the RPV lower head corium behavior and heat transfer to the PRV wall for the reference plant(APR1400) using the ASTEC V2-Rev.1-P2-Beta version. WP6-4: Confirmation of the effect of water ingression model employed in the CORQUENCH 3.03, through the analysis of the effect of water on top of the melt on the cavity concrete ablation process by both MELCOR 1.8.6 and CORQUENCH 3.03 codes, and establishment of an approach to utilize these parameters through the formal review of the MCCI model parameters employed in the MELCOR code. WP7-1: Confirmation of different solidification processes of molten debris particles depending on the compositions by SEM/XRD/EPMA analysis. WP7-2: Benchmark blind/open calculations for code validation against the IRSN ENACCEF experiments and reflection of its result to the SARNET2 WP7-2 reports published in 2011. As its second step, the new benchmark problem has been launched in 2012. WP8-3: ISSAC code analysis to predict the ST behavior during the SGTR accident of the domestic PHWR plant, and preliminary MELCOR analysis for the PHEBUS FPT-3 ST benchmark problem. The foregoing research results and experimental database for main SA issues obtained by this research are expected to be used for resolving SA issue remained in domestic NPPs (operating, to be constructed, future) and enhancing the evaluating capability of Level-2 PSA.

  20. Animal Board Invited Review: Sheep birth distribution in past herds: a review for prehistoric Europe (6th to 3rd millennia BC).

    Science.gov (United States)

    Balasse, M; Tresset, A; Bălăşescu, A; Blaise, E; Tornero, C; Gandois, H; Fiorillo, D; Nyerges, É Á; Frémondeau, D; Banffy, E; Ivanova, M

    2017-12-01

    In temperate latitudes sheep have a seasonal reproductive behaviour, which imposes strong constraints on husbandry in terms of work organization and availability of animal products. During the last 50 years, researchers have focused on understanding the mechanisms driving small ruminants' reproduction cycles and finding ways to control them. This characteristic is inherited from their wild ancestor. However, the history of its evolution over the 10 millennia that separates present day European sheep from their Near Eastern ancestors' remains to be written. This perspective echoes archaeologists' current attempts at reconstructing ancient pastoral societies' socio-economical organization. Information related to birth seasonality may be retrieved directly from archaeological sheep teeth. The methodology consists of reconstructing the seasonal cycle record in sheep molars, through sequential analysis of the stable oxygen isotope composition (δ 18O) of enamel. Because the timing of tooth development is fixed within a species, inter-individual variability in this parameter reflects birth seasonality. A review of the data obtained from 10 European archaeological sites dated from the 6th to the 3rd millennia BC is provided. The results demonstrate a restricted breeding season for sheep: births occurred over a period of 3 to 4 months, from late winter to early summer at latitudes 43°N to 48°N, while a later onset was observed at a higher latitude (59°N). All conclusions concurred with currently held expectations based on present day sheep physiology, which, aside from the historical significance, contributes to the reinforcing of the methodological basis of the approach. Further study in this area will permit regional variability attributable to technical choices, within global schemes, to be fully reported.

  1. Pooled nucleic acid testing increases the diagnostic yield of acute HIV infections in a high-risk population compared to 3rd and 4th generation HIV enzyme immunoassays.

    Science.gov (United States)

    Krajden, Mel; Cook, Darrel; Mak, Annie; Chu, Ken; Chahil, Navdeep; Steinberg, Malcolm; Rekart, Michael; Gilbert, Mark

    2014-09-01

    We compared a 3rd generation (gen) and two 4th gen HIV enzyme immunoassays (EIA) to pooled nucleic acid testing (PNAT) for the identification of pre- and early seroconversion acute HIV infection (AHI). 9550 specimens from males >18 year from clinics attended by men who have sex with men were tested by Siemens ADVIA Centaur(®) HIV 1/O/2 (3rd gen) and HIV Combo (4th gen), as well as by Abbott ARCHITECT(®) HIV Ag/Ab Combo (4th gen). Third gen non-reactive specimens were also tested by Roche COBAS(®) Ampliprep/COBAS® TaqMan HIV-1 Test v.2 in pools of 24 samples. Sensitivity and specificity of the three EIAs for AHI detection were compared. 7348 persons contributed 9435 specimens and had no evidence of HIV infection, 79 (94 specimens) had established HIV infection, 6 (9 specimens) had pre-seroconversion AHI and 9 (12 specimens) had early seroconversion AHI. Pre-seroconversion AHI cases were not detected by 3rd gen EIA, whereas 2/6 (33.3%) were detected by Siemens 4th gen, 4/6 (66.7%) by Abbott 4th gen and 6/6 (100%) by PNAT. All three EIAs and PNAT detected all individuals with early seroconversion AHI. Overall sensitivity/specificity for the EIAs relative to WB or NAT resolved infection status was 93.6%/99.9% for Siemens 3rd gen, 95.7%/99.7% for Siemens 4th gen and 97.9%/99.2% for Abbott 4th gen. While both 4th gen EIAs demonstrated improved sensitivity for AHI compared to 3rd gen EIA, PNAT identified more AHI cases than either 4th gen assay. PNAT is likely to remain a useful strategy to identify AHI in high-risk populations. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. The Child Sport Concussion Assessment Tool 5th Edition (Child SCAT5): Background and rationale.

    Science.gov (United States)

    Davis, Gavin A; Purcell, Laura; Schneider, Kathryn J; Yeates, Keith Owen; Gioia, Gerard A; Anderson, Vicki; Ellenbogen, Richard G; Echemendia, Ruben J; Makdissi, Michael; Sills, Allen; Iverson, Grant L; Dvořák, Jiří; McCrory, Paul; Meeuwisse, Willem; Patricios, Jon; Giza, Christopher C; Kutcher, Jeffrey S

    2017-06-01

    This article presents the Child Sport Concussion Assessment Tool 5th Edition (Child SCAT5). The Sport Concussion Assessment Tool was introduced in 2004, following the 2nd International Conference on Concussion in Sport in Prague, Czech Republic. Following the 4th International Consensus Conference, held in Zurich, Switzerland, in 2012, the SCAT 3rd edition (Child SCAT3) was developed for children aged between 5 and12 years. Research to date was reviewed and synthesised for the 5th International Consensus Conference on Concussion in Sport in Berlin, Germany, leading to the current revision of the test, the Child SCAT5. This article describes the development of the Child SCAT5. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  3. Editing Audio with Audacity

    Directory of Open Access Journals (Sweden)

    Brandon Walsh

    2016-08-01

    Full Text Available For those interested in audio, basic sound editing skills go a long way. Being able to handle and manipulate the materials can help you take control of your object of study: you can zoom in and extract particular moments to analyze, process the audio, and upload the materials to a server to compliment a blog post on the topic. On a more practical level, these skills could also allow you to record and package recordings of yourself or others for distribution. That guest lecture taking place in your department? Record it and edit it yourself! Doing so is a lightweight way to distribute resources among various institutions, and it also helps make the materials more accessible for readers and listeners with a wide variety of learning needs. In this lesson you will learn how to use Audacity to load, record, edit, mix, and export audio files. Sound editing platforms are often expensive and offer extensive capabilities that can be overwhelming to the first-time user, but Audacity is a free and open source alternative that offers powerful capabilities for sound editing with a low barrier for entry. For this lesson we will work with two audio files: a recording of Bach’s Goldberg Variations available from MusOpen and another recording of your own voice that will be made in the course of the lesson. This tutorial uses Audacity 2.1.2, released January 2016.

  4. ICOM2012: 3rd International Conference on the Physics of Optical Materials and Devices (Belgrade, Serbia, 2-6 September 2012)

    Science.gov (United States)

    Dramićanin, Miroslav D.; Antić, Željka; Viana, Bruno

    2013-11-01

    The 3rd International Conference on the Physics of Optical Materials and Devices (ICOM2012) was held in Belgrade (Serbia) from 2 to 6 September 2012 (figure 1). The conference was organized by the Vinča Institute of Nuclear Sciences, University of Belgrade (Serbia) and the Laboratoire de Chimie de la Matière Condensée de Paris (France), and supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia and Optical Society of America. ICOM2012 was a follow-up to the two previous, successful ICOM conferences held in Herceg Novi in 2006 and 2009. The conference aimed at providing a forum for scientists in optical materials to debate on: • Luminescent materials and nanomaterials • Hybrid optical materials (organic/inorganic) • Characterization techniques of optical materials • Luminescence mechanisms and energy transfers • Theory and modeling of optical processes • Ultrafast-laser processing of materials • Optical sensors • Medical imaging • Advanced optical materials in photovoltaics and biophotonics • Photothermal and photoacoustic spectroscopy and phenomena The conference stressed the value of a fundamental scientific understanding of optical materials. A particular accent was put on wide band-gap materials in crystalline, glass and nanocrystalline forms. The applications mainly involved lasers, scintillators and phosphors. Rare earth and transition metal ions introduced as dopants in various hosts were considered, and their impact on the optical properties were detailed in several presentations. This volume contains selected contributions of speakers and participants of the ICOM2012 conference. The conference provided a unique opportunity for about 200 scientists from 32 countries to discuss recent progress in the field of optical materials. During the three and half days, 21 invited talks and 52 contributed lectures were given, with a special event in memory of our dear colleague Professor Dr Tsoltan

  5. The association of moderate renal dysfunction with impaired preference-based health-related quality of life: 3rd Korean national health and nutritional examination survey

    Directory of Open Access Journals (Sweden)

    Lee Hajeong

    2012-04-01

    Full Text Available Abstract Background Only a few large-scale studies have investigated the association between health-related quality of life (HRQOL and renal function. Moreover, the HRQOL of patients with moderate renal dysfunction is frequently underestimated by healthcare providers. This study assessed the impact of renal function on preference-based HRQOL in Korean adult population. Methods We analyzed data for 5,555 adults from the 3rd Korean National Health and Nutritional Examination Survey 2005. The EuroQol-5D (EQ-5D utility score was used to evaluate HRQOL. The study subjects were stratified into three groups based on their estimated glomerular filtration rates (eGFRs: ≥ 90.0, 60.0-89.9 and 30.0-59.9 mL/min/1.73 m2. Individuals with advanced renal dysfunction were excluded from the analysis. Results The proportions of participants who reported problems in each of the five EQ-5D dimensions increased significantly with decreasing eGFR. However, a significant decrease in the EQ-5D utility score was observed among participants with an eGFR of 30.0-59.9 mL/min/1.73 m2. Participants with an eGFR of 30.0-59.9 mL/min/1.73 m2 had an almost 1.5-fold higher risk of impaired health utility (the lowest quartile of EQ-5D utility score compared with those participants with eGFRs ≥ 90.0 mL/min/1.73 m2, after adjustment for age, gender, health-related behaviors, socioeconomic and psychological variables, and other comorbidities. Among the five dimensions of the EQ-5D, an eGFR of 30.0-59.9 mL/min/1.73 m2 was an independent determinant of self-reported problems in the mobility and pain/discomfort dimensions. Conclusions Although age affects the association between renal dysfunction and the EQ-5D, moderate renal dysfunction seems to be an important determinant of impaired health utility in a general population and may affect the mobility and pain/discomfort dimensions of health utility.

  6. Mound No. 24 of the Alebastrovo I Burial Ground and the Problem of Succession Among the Early Nomadic Cultures of the Southern Urals in the 6th – 4th and 3rd – 1st Centuries BC

    Directory of Open Access Journals (Sweden)

    Denis V. Maryksin

    2017-03-01

    Full Text Available The article focuses on one of the burial mounds – Alebastrovo I, which is situated in the middle reaches of the Ural river. The analysis of the burial rite and grave goods reveals the combination of features peculiar of the culture of early nomads from the 6th to the 4th centuries BC and later features typical for the 3rd – 1st centuries BC. The collective nature of the burial in a large square pit (burial no. 2 relates to early features. Such burials are typical for the 5th and 4th centuries BC. But a dagger with a direct crosshair and a crescent-shaped pommel found in the burial belongs to the 3rd – 1st centuries BC. Findings of a mirror, a spoon and a whorl also deserve special attention. On formal grounds a mirror belongs to the type “Skripkin 1.6” – with a flat disk without roll and stick in the form of a triangular stem. They appeared in Sauromatian time, but were not widespread. Most of these mirrors refer to the turn of the eras – the first centuries AD. However, in our view the mirror from Alebastrovo I has the greatest similarity with the mirror disks of the so-called “musical” mirrors, which date back to the 2nd half of the 4th century BC. The bone spoon belongs to the type I, peculiar of the Sauromatian-time things of the 6th – 4th centuries BC. However, the pattern is similar to that on the handle of the bone products of later time – the 3rd – 2nd centuries BC. Clay whorl has a pattern in the form of 4 sectors, decorated with grooves and pits. Analogies are available on this ornament spindles from the 3rd – 2nd centuries BC of the Kara-Abyz culture in the Southern Urals. According to the set of attributes, this burial mound dated to the second half of the 3rd - 2nd centuries BC. The finds from this burial mound confirm the conclusion of the first explorer B. F. Zhelezchikov about continuity of the development of the early nomadic culture of this region in the 6th – 3rd centuries BC.

  7. Precision genome editing

    DEFF Research Database (Denmark)

    Steentoft, Catharina; Bennett, Eric P; Schjoldager, Katrine Ter-Borch Gram

    2014-01-01

    Precise and stable gene editing in mammalian cell lines has until recently been hampered by the lack of efficient targeting methods. While different gene silencing strategies have had tremendous impact on many biological fields, they have generally not been applied with wide success in the field...... of glycobiology, primarily due to their low efficiencies, with resultant failure to impose substantial phenotypic consequences upon the final glycosylation products. Here, we review novel nuclease-based precision genome editing techniques enabling efficient and stable gene editing, including gene disruption...... by introducing single or double-stranded breaks at a defined genomic sequence. We here compare and contrast the different techniques and summarize their current applications, highlighting cases from the field of glycobiology as well as pointing to future opportunities. The emerging potential of precision gene...

  8. Human Germline Genome Editing.

    Science.gov (United States)

    Ormond, Kelly E; Mortlock, Douglas P; Scholes, Derek T; Bombard, Yvonne; Brody, Lawrence C; Faucett, W Andrew; Garrison, Nanibaa' A; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E

    2017-08-03

    With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Genetic Counselors. These groups, as well as the American Society for Reproductive Medicine, Asia Pacific Society of Human Genetics, British Society for Genetic Medicine, Human Genetics Society of Australasia, Professional Society of Genetic Counselors in Asia, and Southern African Society for Human Genetics, endorsed the final statement. The statement includes the following positions. (1) At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human pregnancy. (2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing. There should be no prohibition on making public funds available to support this research. (3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input. Copyright © 2017 American Society of Human Genetics. All rights reserved.

  9. Editing faces in videos

    OpenAIRE

    Amberg, Brian

    2011-01-01

    Editing faces in movies is of interest in the special effects industry. We aim at producing effects such as the addition of accessories interacting correctly with the face or replacing the face of a stuntman with the face of the main actor. The system introduced in this thesis is based on a 3D generative face model. Using a 3D model makes it possible to edit the face in the semantic space of pose, expression, and identity instead of pixel space, and due to its 3D nature allows...

  10. Editing tools. Transcribing and encoding

    NARCIS (Netherlands)

    Spadini, E.

    2015-01-01

    This paper deals with editing tools and editing platforms, i.e. programs used by editors in order to fulfil one or more tasks in the creation of a scholarly digital edition (SDE). Recurring themes in the field of SDEs are the standardization of XML-TEI markup and the success of documentary digital

  11. Beginning to edit physics

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, P.W.

    1995-02-01

    A physicist-turned-editor shows you the basics required for copyediting physics papers (physical quantities, symbols, units, scientific notation, the structure of mathematical expressions, the nature of graphs), and points the way to learning enough ``editorial physics`` to begin substantive editing.

  12. The Craft of Editing

    DEFF Research Database (Denmark)

    Moeran, Brian

    To edit is to make a choice, or series of choices. Will I write a rough draft of this essay in longhand, or hammer it out on my computer? If the latter, what font shall I use? Times New Roman, Book Antiqua, or Garamond? Once I get started, what style shall I adopt: realistic, confessional or impr...

  13. Contaminant hydrogeology. 2. edition

    Energy Technology Data Exchange (ETDEWEB)

    Fetter, C.W.

    1999-08-01

    This book is a major revision of the 1993 edition and includes the important practical concepts that have since emerged. Contents include: mass transport in saturated media; transformation, retardation, and attenuation of solutes; flow and mass transport in the vadose zone; multiphase flow; inorganic chemicals in groundwater; organic compounds in groundwater; groundwater and soil monitoring; and site remediation.

  14. Joint conference of iMEC 2015 (2nd International Manufacturing Engineering Conference & APCOMS 2015 (3rd Asia-Pacific Conference on Manufacturing Systems)

    Science.gov (United States)

    2016-02-01

    The iMEC 2015 is the second International Manufacturing Engineering Conference organized by the Faculty of Manufacturing, Universiti Malaysia Pahang (UMP), held from 12-14th November 2015 in Kuala Lumpur, Malaysia, with a theme "Materials, Manufacturing and Systems for Tomorrow". For the first time, iMEC is organized together with 3rd Asia- Pacific Conference on Manufacturing System (APCOMS 2015) which owned by Fakulti Teknologi Industri, Institut Teknologi Bandung (ITB), Indonesia. This is an extended collaboration between UMP and ITB to intensify knowledge sharing and experiences between higher learning institutions. This conference (iMEC & APCOMS 2015) is a platform for knowledge exchange and the growth of ideas, particularly in manufacturing engineering. The conference aims to bring researchers, academics, scientists, students, engineers and practitioners from around the world together to present their latest findings, ideas, developments and applications related to manufacturing engineering and other related research areas. With rapid advancements in manufacturing engineering, iMEC is an appropriate medium for the associated community to keep pace with the changes. In 2015, the conference theme is “Materials, Manufacturing and Systems for Tomorrow” which reflects the acceleration of knowledge and technology in global manufacturing. The papers in these proceedings are examples of the work presented at the conference. They represent the tip of the iceberg, as the conference attracted over 200 abstracts from Malaysia, Indonesia, Japan, United Kingdom, Australia, India, Bangladesh, South Africa, Turkey and Morocco and 151 full papers were accepted in these proceedings. The conference was run in four parallel sessions with 160 presenters sharing their latest finding in the areas of manufacturing process, systems, advanced materials and automation. The first keynote presentation was given by Prof. B. S. Murthy (IIT, Madras) on "Nanomaterials with Exceptional

  15. The incidence and nature of injuries sustained on grass and 3rd generation artificial turf: a pilot study in elite Saudi National Team footballers.

    Science.gov (United States)

    Almutawa, M; Scott, M; George, K P; Drust, B

    2014-02-01

    To compare the incidence, severity and nature of injuries sustained by Saudi National Team footballers during match-play and training on natural grass and 3rd generation (3G) artificial turf. Injury data was collected on all Saudi National Team players competing at the Gulf Cup (Yemen December 2010: 3G) and the Asian Cup (Qatar January 2011; grass). A total of 49 players were studied (mean ± SD; Age 27 ± 4 yr; body mass 71.4 ± 6.7 kg; height 176.8 ± 6.3 cm; professional playing experience 9 ± 3 yr) of which 31 competed at the Gulf Cup, 32 at the Asian Cup (14 at both). A prospective cohort design was used to investigate the incidence, nature and severity of injuries sustained with data collected using a standardised injury questionnaire. All data were collected by the team physiotherapist with the definition of injury set at any injury that required player and clinician contact. Injury and exposure data were collected and reported for games, training and all football activity. A total of 82 injuries [incidence - 56.1 per 1000 h total game and training exposure] were recorded at the Asian Cup (grass) and 72 injuries [incidence - 37.9 per 1000 h total game and training exposure] were recorded at the Gulf Cup (3G). Incidence data for training, game and all football exposure injury rates were higher when playing on grass. The vast majority of injuries on both surfaces were very minor that, whilst requiring medical attention, did not result in loss of match/training exposure. Injuries that resulted in 1-3 days absence from training or game play had similar incidence rates (Grass: 7.4 vs. 3G: 7.4 injuries per 1000 h exposure). More severe injuries were less frequent but with a higher incidence when playing on grass. Lower limb injuries were the most common in both tournaments with a higher incidence on grass (Grass: 14.2 vs. 3G: 7.9 injuries per 1000 h exposure). Muscle injuries were the most frequent of all injuries with similar incidence rates on

  16. The association of relational and organizational job stress factors with sleep disorder: analysis of the 3rd Korean working conditions survey (2011).

    Science.gov (United States)

    Kim, Gyuree; Min, Bokki; Jung, Jaeyoup; Paek, Domyung; Cho, Sung-Il

    2016-01-01

    Sleep disorder is a disease that causes reduction in quality of life and work efficiency of workers. This study was performed to investigate the relationship between job-related stress factor and sleep disorder among wageworkers in Korea. This study was based on analysis of the 3rd Korean working conditions survey. We analyzed 35,902 workers whose employment status is wageworker. We classified the job-related stress factor into 12 sections. Logistic regression was performed to estimate the relationship between job-related stress factor and sleep disorder and Odds ratio and 95 % CI were calculated using the SPSS version 23.0 program. Many categories of Job-related stress factor were correlated with sleep disorder (8 of 12 for women, 10 of 12 for men). The results of the regression analysis, corrected for general and occupational characteristics, indicated that sleep disorder was significantly correlated with the following categories of job-related stress: discrimination experience (OR 3.37, 95 % CI = 2.49 ~ 4.56 in women, OR 1.96, 95 % CI = 1.53 ~ 2.51 in men), direct customer confrontation (OR 2.72, 95 % CI = 1.91 ~ 3.86 in women, OR 1.99, 95 % CI = 1.45 ~ 2.72 in men), emotional stress (OR 2.01, 95 % CI = 1.30 ~ 3.09 in men), work dissatisfaction (detailed) (OR 1.99, 95 % CI = 1.36 ~ 2.93 in men), work dissatisfaction (overall) (OR 2.30, 95 % CI = 1.66 ~ 3.20 in women, OR 2.40, 95 % CI = 1.88 ~ 3.08 in men), expression of opinion difficulty (OR 0.66, 95 % CI = 0.48 ~ 0.92 in women, OR 0.57, 95 % CI = 0.45 ~ 0.73 in men). A number of studies have reported that stress affects sleep disorder. In this study, many factors suspected to increase the risk of sleep disorder were added to previously known job stress factors. In particular, this study found a strong correlation between work-associated sleep disorder and relational and organizational job stress factors. Sleep disorder

  17. Fan edits and the legacy of The Phantom Edit

    Directory of Open Access Journals (Sweden)

    Joshua Wille

    2014-09-01

    Full Text Available A fan edit can generally be defined as an alternative version of a film or television text created by a fan. It offers a different viewing experience, much as a song remix offers a different listening experience. The contemporary wave of fan edits has emerged during the remix zeitgeist of digital media and at a time when digital video editing technology has become more affordable and popular. The increasing number of alternative versions of films and the works of revisionist Hollywood filmmakers such as George Lucas have contributed to a greater public understanding of cinema as a fluid medium instead of one that exists in a fixed form. The Phantom Edit (2000, a seminal fan edit based on Lucas's Star Wars Episode I: The Phantom Menace (1999, inspired new ranks of fan editors. However, critics have misunderstood fan edits as merely the work of disgruntled fans. In order to provide a critical and historical basis for studies in fan editing as a creative practice, I examine previous interpretations of fan edits in the context of relevant contemporary works, and I use an annotated chronology of The Phantom Edit to trace its influence on subsequent fan editing communities and uncover their relationship with intellectual property disputes.

  18. Video Editing System

    Science.gov (United States)

    Schlecht, Leslie E.; Kutler, Paul (Technical Monitor)

    1998-01-01

    This is a proposal for a general use system based, on the SGI IRIS workstation platform, for recording computer animation to videotape. In addition, this system would provide features for simple editing and enhancement. Described here are a list of requirements for the system, and a proposed configuration including the SGI VideoLab Integrator, VideoMedia VLAN animation controller and the Pioneer rewritable laserdisc recorder.

  19. UN-EDITED VERSION

    Indian Academy of Sciences (India)

    67

    1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. UN-EDITED VERSION ...

  20. Effects of Deep Water Source-Sink Terms in 3rd generation Wave Model SWAN using different wind data in Black Sea

    Science.gov (United States)

    Kirezci, Cagil; Ozyurt Tarakcioglu, Gulizar

    2016-04-01

    Coastal development in Black Sea has increased in recent years. Therefore, careful monitoring of the storms and verification of numerical tools with reliable data has become important. Previous studies by Kirezci and Ozyurt (2015) investigated extreme events in Black Sea using different wind datasets (NCEP's CFSR and ECMWF's operational datasets) and different numerical tools (SWAN and Wavewatch III). These studies showed that significant effect to results is caused by the deep water source-sink terms (wave growth by wind, deep water dissipation of wave energy (whitecapping) and deep water non-linear wave-wave interactions). According to Timmermans(2015), uncertainty about wind forcing and the process of nonlinear wave-wave interactions are found to be dominant in numerical wave modelling. Therefore, in this study deep water source and sink term solution approaches of 3rd generation numerical tool (SWAN model) are tested, validated and compared using the selected extreme storms in Black Sea. 45 different storms and storm like events observed in Black Sea between years 1994-1999 are selected to use in the models. The storm selection depends on the instrumental wave data (significant wave heights, mean wave period and mean wave direction) obtained in NATO-TU Waves project by the deep water buoy measurements at Hopa, Sinop, Gelendzhik, and wind data (mean and peak wind speeds, storm durations) of the regarding events. 2 different wave growth by wind with the corresponding deep water dissipation terms and 3 different wave -wave interaction terms of SWAN model are used in this study. Wave growth by wind consist of two parts, linear growth which is explained by Cavaleri and Malanotte-Rizzoli(1981),and dominant exponential growth. There are two methods in SWAN model for exponential growth of wave, first one by Snyder et al. (1981), rescaled in terms of friction velocity by Komen et. al (1984) which is derived using driving wind speed at 10m elevation with related drag

  1. Revising and editing for translators

    CERN Document Server

    Mossop, Brian

    2014-01-01

    Revising and Editing for Translators provides guidance and learning materials for translation students learning to edit texts written by others, and professional translators wishing to improve their self-revision ability or learning to revise the work of others. Editing is understood as making corrections and improvements to texts, with particular attention to tailoring them to the given readership. Revising is this same task applied to draft translations. The linguistic work of editors and revisers is related to the professional situations in which they work. Mossop offers in-depth coverage of a wide range of topics, including copyediting, style editing, structural editing, checking for consistency, revising procedures and principles, and translation quality assessment. This third edition provides extended coverage of computer aids for revisers, and of the different degrees of revision suited to different texts. The inclusion of suggested activities and exercises, numerous real-world examples, a proposed gra...

  2. The 3rd Report on Climate Change in Catalonia: a joint initiative to bridge the gap between Science and Decision-Making

    Science.gov (United States)

    Queralt, Arnau; Llasat, Maria del Carmen; Serena, Josep Maria; Pont, Isabel

    2017-04-01

    In January 2017 the Government of Catalonia (Advisory Council for the Sustainable Development, Catalan Office for Climate Change, and Meteorological Service of Catalonia) and the Institute for Catalan Studies presented the Third Report on Climate Change in Catalonia, whose aims are (1) to gather and summarise the most recent information on climate change and its effects on the natural and human systems in Catalonia (and to identify existing knowledge gaps), (2) to make recommendations to decision-makers, and (3) to rise decision-makers and citizens awareness on the effects of climate change and the importance of reinforce mitigation and adaptation efforts. Although climate change is a global phenomenon, impacts and subsequent adaptive action may differ across countries and regions. In accordance to this, and with the aim of downscaling the contents of the IPCC reports, the first report on climate change in Catalonia was published in 2005 and was followed by a second edition in 2010. Directly linked to this second report, the Catalan Panel on Climate Change was established. During a year and a half more than 130 authors and 40 scientific and technical revisers (assisted by a board and technical staff from the leading institutions) have participated in the third assessment of climate change in Catalonia. The report updates the observations and projections related to the climate evolution at Catalonia and its impacts, gathering the most advanced scientific knowledge and providing the Catalan Government with sectorial recommendations to face these impacts. After its official launch in January 2017, the report will be presented and discussed with several ministers and officials within the Catalan Government, but also with the main stakeholders. These presentations and dialogue are strategic actions for bridging the gap between Science and Policy-making regarding climate change. An executive summary identifying in a very focused way the main messages arising from the

  3. Proceedings of the Second Forum for the Euro-Japan Academic Networking for Humanities Project held at Venice International University on 2nd and 3rd October, 2012

    OpenAIRE

    AOKI, Saburo; Hattori, Eiji; HANNACHI, Salah; TAMBA, Akira; TUYCHIEV, Mukhiddin

    2013-01-01

    This paper reports on the proceedings of the Second Forum for the Euro-Japan Academic Networking for Humanities Project held at Venice International University on 2nd and 3rd October, 2012.本稿は2012年10月2日、3日に開催された「人文系欧州・日本学術ネットワーキングプロジェクト」第2回フォーラムの議事録である。

  4. Implications And Legal Consequences Of Administrative Misconduct Law: Analysis Of The Performance Of The 3rd Prosecution Mprn Of Justice In The Circuit Court Of Caicó-Rn In Period 2010 2014

    Directory of Open Access Journals (Sweden)

    Winston de Araújo Teixeira

    2016-12-01

    Full Text Available This article aims to analyze and obtain data regarding the performance of the Public Ministry of RN meet the demands of improper conduct and how is the processing of these actions aiming to verify whether, in fact, Law Nº. 8.429/92 (of Misconduct Law administrative, it is an effective mechanism to combat and reprimand corruption. For this we used the historical-deductive method. He employed the documentary research held at the 3rd Prosecutor's Office of the District of Caicó / RN, combined with the data found on the website of the Court of Justice of Rio Grande do Norte state.

  5. Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference

    DEFF Research Database (Denmark)

    Kirchhof, Paulus; Lip, Gregory Y H; Van Gelder, Isabelle C

    2012-01-01

    the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper...... covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section...

  6. REDIdb: the RNA editing database.

    Science.gov (United States)

    Picardi, Ernesto; Regina, Teresa Maria Rosaria; Brennicke, Axel; Quagliariello, Carla

    2007-01-01

    The RNA Editing Database (REDIdb) is an interactive, web-based database created and designed with the aim to allocate RNA editing events such as substitutions, insertions and deletions occurring in a wide range of organisms. The database contains both fully and partially sequenced DNA molecules for which editing information is available either by experimental inspection (in vitro) or by computational detection (in silico). Each record of REDIdb is organized in a specific flat-file containing a description of the main characteristics of the entry, a feature table with the editing events and related details and a sequence zone with both the genomic sequence and the corresponding edited transcript. REDIdb is a relational database in which the browsing and identification of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA sequences or to show the corresponding alignment. In both cases, all editing sites are highlighted in colour and their relative positions are detailed by mousing over. New editing positions can be directly submitted to REDIdb after a user-specific registration to obtain authorized secure access. This first version of REDIdb database stores 9964 editing events and can be freely queried at http://biologia.unical.it/py_script/search.html.

  7. Genome Editing Tools in Plants.

    Science.gov (United States)

    Mohanta, Tapan Kumar; Bashir, Tufail; Hashem, Abeer; Abd Allah, Elsayed Fathi; Bae, Hanhong

    2017-12-19

    Genome editing tools have the potential to change the genomic architecture of a genome at precise locations, with desired accuracy. These tools have been efficiently used for trait discovery and for the generation of plants with high crop yields and resistance to biotic and abiotic stresses. Due to complex genomic architecture, it is challenging to edit all of the genes/genomes using a particular genome editing tool. Therefore, to overcome this challenging task, several genome editing tools have been developed to facilitate efficient genome editing. Some of the major genome editing tools used to edit plant genomes are: Homologous recombination (HR), zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), pentatricopeptide repeat proteins (PPRs), the CRISPR/Cas9 system, RNA interference (RNAi), cisgenesis, and intragenesis. In addition, site-directed sequence editing and oligonucleotide-directed mutagenesis have the potential to edit the genome at the single-nucleotide level. Recently, adenine base editors (ABEs) have been developed to mutate A-T base pairs to G-C base pairs. ABEs use deoxyadeninedeaminase (TadA) with catalytically impaired Cas9 nickase to mutate A-T base pairs to G-C base pairs.

  8. With this Special Edition

    Directory of Open Access Journals (Sweden)

    Oscar Antonio Martínez Molina

    2017-02-01

    Full Text Available With this Special Edition, the refereed Scientific Magazine, published in February 2017, presents a nourished and multidisciplinary theme, from the relationship of Environmental Education, in this ecological sharing man-environment; the social responsibility from the Management environment and the motivational values ​​conducive to the teaching performance in the different educational levels. Twenty-five (25 articles, generated from research production in university environments at the International level, are a signature of the quality of articles / essays presented in this Special Edition. Several reasons motivate the literary pen of our authors, adjusting to the rhythm of the times and the use of new technologies; and in correspondence with the care of the environment, this way of disseminating and making visible the scientific contents of humanistic and social court, support the care and protection of the forests, being an online production, in the Cloud. Thanks to the support of the Instituto Internacional de Investigación y Desarrollo Tecnológico Educativo INDTEC, CA, Scientific Magazine has been able to develop from the cooperative work of the people who compose its different committees: Editorial Academic Committee, Academic Scientific Committee and the Arbitrators in the review and valuation of the quality of the articles. With these assets, the Scientific Magazine, opening to the general public and especially to the academic new intellectual horizons.

  9. Natural Hazards, Second Edition

    Science.gov (United States)

    Rouhban, Badaoui

    Natural disaster loss is on the rise, and the vulnerability of the human and physical environment to the violent forces of nature is increasing. In many parts of the world, disasters caused by natural hazards such as earthquakes, floods, landslides, drought, wildfires, intense windstorms, tsunami, and volcanic eruptions have caused the loss of human lives, injury, homelessness, and the destruction of economic and social infrastructure. Over the last few years, there has been an increase in the occurrence, severity, and intensity of disasters, culminating with the devastating tsunami of 26 December 2004 in South East Asia.Natural hazards are often unexpected or uncontrollable natural events of varying magnitude. Understanding their mechanisms and assessing their distribution in time and space are necessary for refining risk mitigation measures. This second edition of Natural Hazards, (following a first edition published in 1991 by Cambridge University Press), written by Edward Bryant, associate dean of science at Wollongong University, Australia, grapples with this crucial issue, aspects of hazard prediction, and other issues. The book presents a comprehensive analysis of different categories of hazards of climatic and geological origin.

  10. NIOSH Manual of Analytical Methods (third edition). Fourth supplement

    Energy Technology Data Exchange (ETDEWEB)

    1990-08-15

    The NIOSH Manual of Analytical Methods, 3rd edition, was updated for the following chemicals: allyl-glycidyl-ether, 2-aminopyridine, aspartame, bromine, chlorine, n-butylamine, n-butyl-glycidyl-ether, carbon-dioxide, carbon-monoxide, chlorinated-camphene, chloroacetaldehyde, p-chlorophenol, crotonaldehyde, 1,1-dimethylhydrazine, dinitro-o-cresol, ethyl-acetate, ethyl-formate, ethylenimine, sodium-fluoride, hydrogen-fluoride, cryolite, sodium-hexafluoroaluminate, formic-acid, hexachlorobutadiene, hydrogen-cyanide, hydrogen-sulfide, isopropyl-acetate, isopropyl-ether, isopropyl-glycidyl-ether, lead, lead-oxide, maleic-anhydride, methyl-acetate, methyl-acrylate, methyl-tert-butyl ether, methyl-cellosolve-acetate, methylcyclohexanol, 4,4'-methylenedianiline, monomethylaniline, monomethylhydrazine, nitric-oxide, p-nitroaniline, phenyl-ether, phenyl-ether-biphenyl mixture, phenyl-glycidyl-ether, phenylhydrazine, phosphine, ronnel, sulfuryl-fluoride, talc, tributyl-phosphate, 1,1,2-trichloro-1,2,2-trifluoroethane, trimellitic-anhydride, triorthocresyl-phosphate, triphenyl-phosphate, and vinyl-acetate.

  11. Annotation in Digital Scholarly Editions

    NARCIS (Netherlands)

    Boot, P.; Haentjens Dekker, R.

    2016-01-01

    Annotation in digital scholarly editions (of historical documents, literary works, letters, etc.) has long been recognized as an important desideratum, but has also proven to be an elusive ideal. In so far as annotation functionality is available, it is usually developed for a single edition and

  12. Fundamentals of Welding. Teacher Edition [and] Student Edition [and] Student Workbook. Second Edition.

    Science.gov (United States)

    Fortney, Clarence; Gregory, Mike; New, Larry

    Teacher and student editions and a student workbook for fundamentals of welding comprise the first of six in a series of competency-based instructional materials for welding programs. Introductory pages in the teacher edition are training and competency profile, instructional/task analysis, basic skills icons and classifications, basic skills…

  13. Oxyacetylene Welding and Oxyfuel Cutting. Third Edition. Teacher Edition [and] Student Edition [and] Student Workbook.

    Science.gov (United States)

    Knapp, John; Harper, Eddie

    This Oklahoma curriculum guide, which includes a teacher edition, a student edition, and a student workbook, provides three units for a course on oxyacetylene welding, oxyfuel cutting, and cutting done with alternative fuels such as MAPP, propane, and natural gas. The three units are: "Oxyacetylene Welding"; "Oxyfuel Cutting";…

  14. Residential and Light Commercial HVAC. Teacher Edition and Student Edition. Second Edition.

    Science.gov (United States)

    Stephenson, David

    This package contains teacher and student editions of a residential and light commercial heating, ventilation, and air conditioning (HVAC) course of study. The teacher edition contains information on the following: using the publication; national competencies; competency profile; related academic and workplace skills list; tools, equipment, and…

  15. Tool steels. 5. edition

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, G.; Krauss, G.; Kennedy, R.

    1998-12-31

    The revision of this authoritative work contains a significant amount of new information from the past nearly two decades presented in an entirely new outline, making this a must have reference for engineers involved in tool-steel production, as well as in the selection and use of tool steels in metalworking and other materials manufacturing industries. The chapter on tool-steel manufacturing includes new production processes, such as electroslag refining, vacuum arc remelting, spray deposition processes (Osprey and centrifugal spray), and powder metal processing. The seven chapters covering tool-steel types in the 4th Edition have been expanded to 11 chapters covering nine main groups of tool steels as well as other types of ultrahigh strength steels sometimes used for tooling. Each chapter discusses in detail processing, composition, and applications specific to the particular group. In addition, two chapters have been added covering surface modification and trouble shooting production and performance problems.

  16. Current practice of epidemiology in Africa: highlights of the 3rd conference of the African epidemiological association and 1st conference of the Cameroon society of epidemiology, Yaoundé, Cameroon, 2014.

    Science.gov (United States)

    Nkwescheu, Armand Seraphin; Fokam, Joseph; Tchendjou, Patrice; Nji, Akindeh; Ngouakam, Hermann; Andre, Bita Fouda; Joelle, Sobngwi; Uzochukwu, Benjamin; Akinroye, Kingsley; Mbacham, Wilfred; Colizzi, Vittorio; Leke, Rose; Victora, Cesar

    2015-01-01

    As the study of disease occurrence and health indicators in human populations, Epidemiology is a dynamic field that evolves with time and geographical context. In order to update African health workers on current epidemiological practices and to draw awareness of early career epidemiologists on concepts and opportunities in the field, the 3(rd) African Epidemiology Association and the 1st Cameroon Society of Epidemiology Conference was organized in June 2-6, 2014 at the Yaoundé Mont Febe Hotel, in Cameroon. Under the theme«Practice of Epidemiology in Africa: Stakes, Challenges and Perspectives», the conference attracted close to five hundred guest and participants from all continents. The two main programs were the pre-conference course for capacity building of African Early Career epidemiologists, and the conference itself, providing a forum for scientific exchanges on recent epidemiological concepts, encouraging the use of epidemiological methods in studying large disease burden and neglected tropical diseases; and highlighting existing opportunities.

  17. Real-World Use of 3rd Line Therapy for Multiple Myeloma in Austria: An Austrian Myeloma Registry (AMR Analysis of the Therapeutic Landscape and Clinical Outcomes prior to the Use of Next Generation Myeloma Therapeutics.

    Directory of Open Access Journals (Sweden)

    Ella Willenbacher

    Full Text Available Clinical trials demonstrate improving survival in patients with multiple myeloma (MM after treatment. However, it is unclear whether increased survival translates to a similar benefit in a real world setting.We analyzed the overall survival of 347 multiple myeloma patients in Austria by means of a national registry (AMR, focused on results from 3rd and later lines of therapy. This benchmark was chosen to define a baseline prior to the broad application of upcoming 2nd generation drugs (carfilzomib, pomalidomide.Projected 10 years survival for patients with MM in Austria is estimated to be 56% in patients diagnosed in between the years 2011-2014, 21% in patients with a diagnosis made between 2000-2005, and 39% in those with a diagnosis made between 2006-2010. For the same intervals a significant increase in the use of both bortezomib, lenalidomide and thalidomide-so called IMiDs (from 2005 onwards and their simultaneous use in combination therapies (from 2010 onwards could be shown. The use of autologous transplantation (ASCT remained more or less constant at ~ 35% of patients in the 1st line setting over the whole period, comparing well to international practice patterns, while the use of 2nd line ASCT increased from 5.5% to 18.7% of patients. Patients in 3rd or later line treatment (n = 105, showed that even in relapsed and refractory disease median survival was 27 months with a considerable proportion of long-term survivors (~20%.With the expected emergence of additional active anti-myeloma compounds, we aim to assess survival in patients with relapsed and refractory MM.

  18. Marine botany. Second edition

    Energy Technology Data Exchange (ETDEWEB)

    Dawes, C.J. [Univ. of South Florida, Tampa, FL (United States)

    1998-12-01

    Marine plants are a diverse group that include unicellular algae, seaweeds, seagrasses, salt marshes, and mangrove forests. They carry out a variety of ecological functions and serve as the primary producers in coastal wetlands and oceanic waters. The theme that connects such a wide variety of plants is their ecology, which was also emphasized in the 1981 edition. The goal of this revision is to present taxonomic, physiological, chemical, and ecological aspects of marine plants, their adaptations, and how abiotic and biotic factors interact in their communities. The data are presented in a concise, comparative manner in order to identify similarities and differences between communities such as salt marsh and mangroves or subtidal seaweeds and seagrasses. To accomplish this, the text is organized into five chapters that introduce the marine habitats, consider abiotic and biotic factors, and anthropogenic influences on the communities followed by seven chapters that deal with microalgae, seaweeds, salt marshes, mangroves, seagrasses, and coral reefs. Two appendixes are included; one presents simple field techniques and the other is a summary of seaweed uses.

  19. Posttranscriptional recoding by RNA editing.

    Science.gov (United States)

    Maas, Stefan

    2012-01-01

    The posttranscriptional recoding of nuclear RNA transcripts has emerged as an important regulatory mechanism during eukaryotic gene expression. In particular the deamination of adenosine to inosine (interpreted by the translational machinery as a guanosine) is a frequent event that can recode the meaning of amino acid codons in translated exons, lead to structural changes in the RNA fold, or may affect splice consensus or regulatory sequence sites in noncoding exons or introns and modulate the biogenesis of small RNAs. The molecular mechanism of how the RNA editing machinery and its substrates recognize and interact with each other is not understood well enough to allow for the ab initio delineation of bona fide RNA editing sites. However, progress in the identification of various physiological modification sites and their characterization has given important insights regarding molecular features and events critical for productive RNA editing reactions. In addition, structural studies using components of the RNA editing machinery and together with editing competent substrate molecules have provided information on the chemical mechanism of adenosine deamination within the context of RNA molecules. Here, I give an overview of the process of adenosine deamination RNA editing and describe its relationship to other RNA processing events and its currently established roles in gene regulation. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Editörlerden

    Directory of Open Access Journals (Sweden)

    Sibel Sakarya

    2015-12-01

    Full Text Available Sevgili okurlar2015 yılının bu son sayısında size dergimizle ilgili bazı özet bilgileri vermek ve son gelişmeleri paylaşmak istiyoruz. Türkiye Halk Sağlığı Dergisinde 2015 yılı içinde, 14 orijinal makale, 1 meta analiz ve 2 kısa rapor olmak üzere toplam 17 araştırma makalesi yayımlanmıştır. Ayrıca 3 editöre mektup, 1 tartışma ve 1 alandan notlar yazısını sizlere ulaştırdık. Daha önceki yıllarla karşılaştırdığımızda yayımlanan yazı sayısı açısından değil ama yazıların niteliği olarak bir ilerleme olduğunu söyleyebiliriz.  Yazıların niteliğinin artırılması ile ilgili çabalarımız sürmekte. Bu amaçla dergimiz editörleri 18.Ulusal Halk Sağlığı Kongresi’nde yazarlık ile ilgili bir kurs düzenlediler. Diğer taraftan dergimizin kurumsal altyapısında önemli değişiklikler yapıldı. Derginin görünürlüğünü ve standartlarını yükseltmek için uluslararası dizinlere girme çabalarını sürdürüyoruz. İlk olarak “Açık Erişim Dergileri Dizini  (DOAJ- The Directory of Open Access Journals başvuru hazırlıklarımız tamamlandı. DOAJ 10,000 den fazla açık erişimli hakemli dergilerin dizinini oluşturan, merkezi İsveç-Lund üniversitesinde olan bir kurum. Bu üyeliğin Dergimizin görünürlüğünü artıracağını ve dış denetimler için bir referans olacağını düşünüyoruz. İkinci olarak çok önem verdiğimiz etik konusunda kurumsallaşmamızı sağlayacak “Yayın Etiği Komitesi” (Committee on Publication Ethics- COPE başvurusu için çalışmalar tamamlandı. COPE hakemli dergi editörleri ve yayımcılarının oluşturduğu bir komite ve böylelikle yayımcılıkla ilgili uluslararası standartları izleyeceğimizi garanti altına almış oluyoruz. COPE kuralları aynı zamanda “Dünya Tıbbi Editörler Birliği (WAME, DOAJ standartları ile de birlikte değerlendirilen bir kurum.Ayrıca  Kasım 2015 ayı itibari ile dergimizin

  1. ELECTIONS PENSION FUND 3rd candidate

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : Hauviller First Name : Claude Dear colleague of CERN and ESO, For the first time, I am standing and requesting your support to become a member of the Governing Board of our Pension Fund. CERN staff member since 1974, I have already carried elective mandates: I have been Delegate to the Staff Council and Member of the Senior Staff Consultative Committee (the Nine). For the majority of us, our Pension Fund is our only social provident scheme and source of retirement income; I believe I can usefully contribute to its successful management and help ensure its balance. Our Fund reaches its majority: soon, there will be more beneficiaries tha...

  2. RAVE 3rd data release (Siebert+, 2011)

    NARCIS (Netherlands)

    Siebert, A.; Williams, M.; Siviero, A.; Reid, W.; Boeche, C.; Steinmetz, M.; Fulbright, J.; Munari, U.; Zwitter, T.; Watson, F. G.; Wyse, R. F. G.; de Jong, R.S.; Enke, H.; Anguiano, B.; Burton, D.; Cass, C. J. P.; Fiegert, K.; Hartley, M.; Ritter, A.; Russel, K. S.; Stupar, M.; Bienayme, O.; Freeman, K. C.; Gilmore, G.; Grebel, E. K.; Helmi, A.; Navarro, J. F.; Binney, J.; Bland-Hawthorn, J.; Campbell, R.; Famaey, B.; Gerhard, O.; Gibson, B. K.; Matijevic, G.; Parker, Q. A.; Seabroke, G. M.; Sharma, S.; Smith, M. C.; Wylie-de Boer, E.

    Spectroscopic radial velocities for 83,072 stars in the Milky-Way southern hemisphere using the 6dF instrument at the AAO. Stellar parameters are published for a set of 39,833 stars belonging to the second and third years of observation.

  3. 3rd Annual Workshop on Inverse Problem

    CERN Document Server

    2015-01-01

    This proceeding volume is based on papers presented on the Third Annual Workshop on Inverse Problems which was organized by the Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, and took place in May 2013 in Stockholm. The purpose of this workshop was to present new analytical developments and numerical techniques for solution of inverse problems for a wide range of applications in acoustics, electromagnetics, optical fibers, medical imaging, geophysics, etc. The contributions in this volume reflect these themes and will be beneficial to researchers who are working in the area of applied inverse problems.

  4. 3rd School on Attractor Mechanism

    CERN Document Server

    SAM 2007; The Attractor Mechanism: Proceedings of the INFN-Laboratori Nazionali di Frascati School 2007

    2010-01-01

    This book is based upon lectures presented in June 2007 at the INFN-Laboratori Nazionali di Frascati School on Attractor Mechanism, directed by Stefano Bellucci. The symposium included such prestigious lecturers as S. Ferrara, M. Gunaydin, P. Levay, and T. Mohaupt. All lectures were given at a pedagogical, introductory level, which is reflected in the specific "flavor" of this volume. The book also benefits from extensive discussions about, and related reworking of, the various contributions. In addition, this volume contains contributions originating from short presentations of rece

  5. 3rd International Conference on Numerical Combustion

    CERN Document Server

    Larrouturou, Bernard; Numerical Combustion

    1989-01-01

    Interest in numerical combustion is growing among applied mathematicians, physicists, chemists, engine manufacturers and many industrialists. This proceedings volume contains nine invited lectures and twenty seven contributions carefully selected by the editors. The major themes are numerical simulation of transsonic and supersonic combustion phenomena, the study of supersonic reacting mixing layers, and turbulent combustion. Emphasis is laid on hyperbolic models and on numerical simulations of hydrocarbon planes with a complete set of chemical reactions carried out in two-dimensional geometries as well as on complex reactive flow simulations.

  6. 3rd Bayesian Young Statisticians Meeting

    CERN Document Server

    Lanzarone, Ettore; Villalobos, Isadora; Mattei, Alessandra

    2017-01-01

    This book is a selection of peer-reviewed contributions presented at the third Bayesian Young Statisticians Meeting, BAYSM 2016, Florence, Italy, June 19-21. The meeting provided a unique opportunity for young researchers, M.S. students, Ph.D. students, and postdocs dealing with Bayesian statistics to connect with the Bayesian community at large, to exchange ideas, and to network with others working in the same field. The contributions develop and apply Bayesian methods in a variety of fields, ranging from the traditional (e.g., biostatistics and reliability) to the most innovative ones (e.g., big data and networks).

  7. 3rd International symposium on ambient intelligence

    CERN Document Server

    Tapia, Dante I; Novais, Paulo; ISAmI 2012; Ambient Intelligence : Software and Applications

    2012-01-01

    Ambient Intelligence (AmI) is a recent paradigm emerging from Artificial Intelligence (AI), where computers are used as proactive tools assisting people with their day-to-day activities, making everyone’s life more comfortable. Another main concern of AmI originates from the human computer interaction domain and focuses on offering ways to interact with systems in a more natural way by means user friendly interfaces. This field is evolving quickly as can be witnessed by the emerging natural language and gesture based types of interaction. The inclusion of computational power and communication technologies in everyday objects is growing and their embedding into our environments should be as invisible as possible. In order for AmI to be successful, human interaction with computing power and embedded systems in the surroundings should be smooth and happen without people actually noticing it. The only awareness people should have arises from AmI: more safety, comfort and wellbeing, emerging in a natural and inh...

  8. 3rd International Conference of Serviceology

    CERN Document Server

    Spohrer, James; Kwan, Stephen; Takenaka, Takeshi

    2017-01-01

    Services are key activities in a globalized economy and they also underlie the quality of life of local residents. The advanced work presented in this book was selected from the proceedings of the Third International Conference on Serviceology (ICServ2015), held July 7–9, 2015, in San Jose, CA, USA. The conference was supported by the Society for Serviceology. The society was established in 2012 in Japan to explore the scientific systematization of services and to promote technological developments for solutions to industrial issues. This book provides a useful general guide to the state of the art in the theory and practice of services. It can also serve as a valuable reference book for researchers in a wide range of fields from engineering to marketing and economics.

  9. The 3rd DBCLS BioHackathon

    DEFF Research Database (Denmark)

    Katayama, Toshiaki; Wilkinson, Mark D; Micklem, Gos

    2013-01-01

    goal of producing Semantic Web data from their respective resources, and/or consuming or interacting those data using their tools and interfaces. We discussed on topics including guidelines for designing semantic data and interoperability of resources. We consequently developed tools and clients...

  10. Ethnographical Research in 3rd World Countries

    DEFF Research Database (Denmark)

    Madsen, Ulla Ambrosius

    2002-01-01

    This paper focuses on Etnografphic Research as a means for generating knowledge about the issues related to education - school learning and bringing up. The example is taken from a research project carried out in Nepal by students recruited from the Ministery of Education. The point is that their...

  11. 3rd Conference on Microactuators and Micromechanisms

    CERN Document Server

    Ananthasuresh, Gondi; Corves, Burkhard; Petuya, Victor

    2015-01-01

    This book contains applications of micromechanisms and microactuators in several very modern technical fields such as mechatronics, biomechanics, machines, micromachines, robotics and apparatuses. In connection with its topic, the work combines the theoretical results with experimental tests on micromechanisms and microactuators. The book presents the most recent research advances in Machine and Mechanisms Science. It includes the accepted reviewed papers of researchers specialized in the topics of the conference: microactuators and micro-assembly, micro sensors involving movable solids, micro-opto-mechanical devices, mechanical tools for cell and tissue studies, micromanipulation and micro-stages, micro-scale flight and swimming, micro-robotics and surgical tools, micron-scale power generation, miniature manufacturing machines, micromechatronics and micro-mechanisms, biomechanics micro and nano scales and control issues in microsystems.  The presented applications of micromechanisms and microactuators i...

  12. Big coal book 2002. 3rd. ed.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The book provides a wide collection of information for the international coal market. An introductory review of the coal market in 2001 and insight into 2002 is followed by a chapter giving statistics (of exports, imports, coal production, consumption and freight rates). Chapter 3 reviews issues facing coal producers and gives a company listing of major coal producers throughout the world. This format is followed for coal consumers, coal traders, coal ports, and the coal transportation sector. Company listings are also given for ship owners, shipbrokers, rail companies, barge companies and petcoke producers. Detailed coal specifications are given for both producers and consumers and there is a complete set of indexes.

  13. 3rd international conference, LDIC 2012

    CERN Document Server

    Scholz-Reiter, Bernd; Thoben, Klaus-Dieter

    2013-01-01

    The volume comprises the proceedings of the third International Conference on Dynamics in Logistics LDIC 2012. The scope of the conference targeted the identification, analysis, and description of the dynamics of logistic processes and networks. The spectrum ranged from the modeling and planning of processes and innovative methods like autonomous control and knowledge management to the new technologies provided by radio frequency identification, mobile communication, and networking. The growing dynamics in the area of logistics poses completely new challenges: Logistic processes and networks must rapidly and flexibly adapt to continuously changing conditions. LDIC 2012 provided a venue for researchers from academia and industry interested in the technical advances in dynamics in logistics. The conference addressed research in logistics from a wide range of fields, e.g. engineering, computer science and operations research. The volume consists of two invited papers and of 49 contributed papers divided into var...

  14. 3rd Turbulence and Interactions Conference

    CERN Document Server

    Estivalezes, Jean-Luc; Gleize, Vincent; Lê, Thien-Hiep; Terracol, Marc; Vincent, Stéphane

    2014-01-01

    The book presents a snapshot of the state-of-art in the field of turbulence modeling and covers the latest developments concerning direct numerical simulations, large eddy simulations, compressible turbulence, coherent structures, two-phase flow simulation, and other related topics. It provides readers with a comprehensive review of both theory and applications, describing in detail the authors’ own experimental results. The book is based on the proceedings of the third Turbulence and Interactions Conference (TI 2012), which was held on June 11-14 in La Saline-les-Bains, La Réunion, France, and includes both keynote lectures and outstanding contributed papers presented at the conference. This multifaceted collection, which reflects the conference´s emphasis on the interplay of theory, experiments and computing in the process of understanding and predicting the physics of complex flows and solving related engineering problems, offers a practice-oriented guide for students, researchers and professionals in ...

  15. 3rd International Conference on Network Analysis

    CERN Document Server

    Kalyagin, Valery; Pardalos, Panos

    2014-01-01

    This volume compiles the major results of conference participants from the "Third International Conference in Network Analysis" held at the Higher School of Economics, Nizhny Novgorod in May 2013, with the aim to initiate further joint research among different groups. The contributions in this book cover a broad range of topics relevant to the theory and practice of network analysis, including the reliability of complex networks, software, theory, methodology, and applications.  Network analysis has become a major research topic over the last several years. The broad range of applications that can be described and analyzed by means of a network has brought together researchers, practitioners from numerous fields such as operations research, computer science, transportation, energy, biomedicine, computational neuroscience and social sciences. In addition, new approaches and computer environments such as parallel computing, grid computing, cloud computing, and quantum computing have helped to solve large scale...

  16. 3rd BRAZILIAN CONSENSUS ON Helicobacter pylori

    Directory of Open Access Journals (Sweden)

    Luiz Gonzaga Coelho

    2013-04-01

    Full Text Available Significant progress has been obtained since the Second Brazilian Consensus Conference on Helicobacter pylori Infection held in 2004, in São Paulo, SP, Brazil, and justify a third meeting to establish updated guidelines on the current management of H. pylori infection. The Third Brazilian Consensus Conference on H pylori Infection was organized by the Brazilian Nucleus for the Study of Helicobacter, a Department of the Brazilian Federation of Gastroenterology and took place on April 12-15, 2011, in Bento Gonçalves, RS, Brazil. Thirty-one delegates coming from the five Brazilian regions and one international guest, including gastroenterologists, pathologists, epidemiologists, and pediatricians undertook the meeting. The participants were allocated in one of the five main topics of the meeting: H pylori, functional dyspepsia and diagnosis; H pylori and gastric cancer; H pylori and other associated disorders; H pylori treatment and retreatment; and, epidemiology of H pylori infection in Brazil. The results of each subgroup were submitted to a final consensus voting to all participants. Relevant data were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. Seventy per cent and more votes were considered as acceptance for the final statement. This article presents the main recommendations and conclusions to guide Brazilian doctors involved in the management of H pylori infection.

  17. Schoolhouse Systems Project: SSP. 3rd Report.

    Science.gov (United States)

    Florida State Dept. of Education, Tallahassee.

    This brochure provides statistical bid breakdown for Programs 1A and 2 of the Florida Schoolhouse Systems Project. Tabular information is provided on bidders, compatible building subsystems, bid tabulation by compatibility, "per school" building subsystems, nominated bidders and lump sums, and a comparison of programs 1A and 2 bids. Data…

  18. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-01

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed high-level operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques.

  19. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-12

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  20. Editörden

    Directory of Open Access Journals (Sweden)

    Nadir Arıcan

    2007-04-01

    Full Text Available Değerli Adli Bilimci’ler, Dergimizin ilk baskısının yapıldığı 1996 yılından 2006 yılı sonuna kadar 11 ciltten oluşan dizisini ara vermeden kesintisiz olarak yayınlanma başarısını gösteren Adli Tıp Bülteni Yayın Kurulu adına saygı ile selamlıyoruz. Dergimizin 12. cildinin ilk sayısı, yayın kurulundaki görev değişikliği ile elinize ulaşıyor. “Adli Tıp Bülteni”ni tüm olumsuz koşullara karşın, siz alana emek veren adli bilimcilerin de büyük desteği ile yayın hayatım başarı ile sürdürdü. Bu başarıda başta editörlerimiz sayın Prof. Dr. Serpil Salaçin ve sayın Prof. Dr. Şebnem Korur Fincancı ile yayın kurulunda görev almış meslektaşlarımıza teşekkür ediyor ve desteklerinin artarak devam edeceğini ümit ediyoruz. Adli Tıp Bülteni, ilk editörü sayın Prof. Dr. Serpil Salaçin’in bültenin 1. sayısında belirttiği amaca uygun olarak, her geçen gün daha da güçlenerek yayın hayatını sürdürmektedir. Yayın akışında zaman zaman kesintiler olsa da, amacı doğrultusunda “alanındaki bilgi akışını sağlama ve bilimsel gelişmelerin önemli bir parçası olma özelliğini” Adli Tıp Uzmanları Derneği’nin resmi bilimsel yayın organı kimliği ile devam ettirmektedir. Hedefleri doğrultusunda uluslararası indekslerce taranan bir dergi olma yolunda ilk adımını atan dergimizin bu alandaki çalışmaları sayın Prof. Dr. Şebnem Korur Fincancı tarafından yürütülmektedir. Görevini genç meslektaşına devretmiş olsa da alanımızdaki uluslar arası deneyimi ile Adli Tıp Bülteni’ni çok farklı noktalara taşıyacağı inancındayım. Bu alanda yapacağı katkılardan dolayı sayın hocama biz kez daha teşekkür etmek istiyorum. Bundan böyle Adli Tıp Bülteni’ne yayınlanmak üzere gönderdiğiniz çalışmalarınızın değerlendirmesini daha hızlı yapabilmek ve baskı aşamasına getirmek amacı ile iletişimi elektronik ortamda yapmaya

  1. Understanding Editing Behaviors in Multilingual Wikipedia.

    Science.gov (United States)

    Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H

    2016-01-01

    Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  2. Understanding Editing Behaviors in Multilingual Wikipedia.

    Directory of Open Access Journals (Sweden)

    Suin Kim

    Full Text Available Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  3. Human coding RNA editing is generally nonadaptive

    Science.gov (United States)

    Xu, Guixia; Zhang, Jianzhi

    2014-01-01

    Impairment of RNA editing at a handful of coding sites causes severe disorders, prompting the view that coding RNA editing is highly advantageous. Recent genomic studies have expanded the list of human coding RNA editing sites by more than 100 times, raising the question of how common advantageous RNA editing is. Analyzing 1,783 human coding A-to-G editing sites, we show that both the frequency and level of RNA editing decrease as the importance of a site or gene increases; that during evolution, edited As are more likely than unedited As to be replaced with Gs but not with Ts or Cs; and that among nonsynonymously edited As, those that are evolutionarily least conserved exhibit the highest editing levels. These and other observations reveal the overall nonadaptive nature of coding RNA editing, despite the presence of a few sites in which editing is clearly beneficial. We propose that most observed coding RNA editing results from tolerable promiscuous targeting by RNA editing enzymes, the original physiological functions of which remain elusive. PMID:24567376

  4. Beginning XML, 5th Edition

    CERN Document Server

    Fawcett, Joe; Quin, Liam R E

    2012-01-01

    A complete update covering the many advances to the XML language The XML language has become the standard for writing documents on the Internet and is constantly improving and evolving. This new edition covers all the many new XML-based technologies that have appeared since the previous edition four years ago, providing you with an up-to-date introductory guide and reference. Packed with real-world code examples, best practices, and in-depth coverage of the most important and relevant topics, this authoritative resource explores both the advantages and disadvantages of XML and addresses the mo

  5. Language Editing at Astronomy & Astrophysics

    Science.gov (United States)

    Adams, J.

    2011-07-01

    In 2002, the A&A Board of Directors voted that all articles must be written in English and decided to improve the overall quality of the language in the articles with the help of a team of language editors. This article reviews the general advantages of editing the English expression and describes both the aims of this effort and its place in the full publication process. This is followed by the Guide to language editing that has been available on the Journal's website for several years now.

  6. Learning Advanced Post-editing

    DEFF Research Database (Denmark)

    Alabau, Vicente; Carl, Michael; Casacuberta, Francisco

    2016-01-01

    This chapter reports the results of a longitudinal study (LS14) in which the CASMACAT post-editing workbench was tested with interactive translation prediction (ITP). Whereas previous studies with the CASMACAT workbench (Sanchis-Trilles et al., Machine Translation, 2014) or similar systems (Langl...... in uncovering any specific profiles of translators depending on personal factors such as previous experience in post-editing and typing skills. Finally, the aim was also to collect feedback from the post-editors in order to know more about their views regarding this type of technology....

  7. Boneless Pose Editing and Animation

    DEFF Research Database (Denmark)

    Bærentzen, Jakob Andreas; Hansen, Kristian Evers; Erleben, Kenny

    2007-01-01

    In this paper, we propose a pose editing and animation method for triangulated surfaces based on a user controlled partitioning of the model into deformable parts and rigid parts which are denoted handles. In our pose editing system, the user can sculpt a set of poses simply by transforming...... problem in order to obtain the interpolation weights. While the system can be used simply for building poses, it is also an animation system. The user can specify a path for a given constraint and the model is animated correspondingly....

  8. Handbook of ecotoxicology, second edition

    Science.gov (United States)

    Hoffman, David J.; Rattner, Barnett A.; Burton, G. Allen; Cairns, John

    2003-01-01

    Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. This authoritative work is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

  9. Delivery technologies for genome editing.

    Science.gov (United States)

    Yin, Hao; Kauffman, Kevin J; Anderson, Daniel G

    2017-06-01

    With the recent development of CRISPR technology, it is becoming increasingly easy to engineer the genome. Genome-editing systems based on CRISPR, as well as transcription activator-like effector nucleases (TALENs) and zinc-finger nucleases (ZFNs), are becoming valuable tools for biomedical research, drug discovery and development, and even gene therapy. However, for each of these systems to effectively enter cells of interest and perform their function, efficient and safe delivery technologies are needed. This Review discusses the principles of biomacromolecule delivery and gene editing, examines recent advances and challenges in non-viral and viral delivery methods, and highlights the status of related clinical trials.

  10. Shielded Metal Arc Pipe Welding. Teacher Edition. Second Edition.

    Science.gov (United States)

    Fortney, Clarence; And Others

    This second edition of the shielded metal arc pipe welding curriculum guide presents both basic and advanced pipe welding skills. All specifications for procedure and welder qualification are presented according to national standards. The standards also include the test position for both groove and fillet pipe welding. The guide contains three…

  11. Gas Tungsten Arc Welding and Plasma Arc Cutting. Teacher Edition [and] Student Edition [and] Student Workbook. Second Edition.

    Science.gov (United States)

    Harper, Eddie; Knapp, John

    This packet of instructional materials for a gas tungsten arc welding (GTAW) and plasma arc cutting course is comprised of a teacher edition, student edition, and student workbook. The teacher edition consists of introductory pages and teacher pages. Introductory pages include training and competency profile, state duty/task crosswalk,…

  12. Gas Metal Arc Welding and Flux-Cored Arc Welding. Third Edition. Teacher Edition [and] Student Edition [and] Student Workbook.

    Science.gov (United States)

    Knapp, John; Harper, Eddie

    This packet, containing a teacher's edition, a student edition, and a student workbook, introduces students to high deposition welding and processes for "shielding" a weld. In addition to general information, the teacher edition consists of introductory pages and teacher pages, as well as unit information that corresponds to the…

  13. RNA editing machinery in plant organelles.

    Science.gov (United States)

    Yan, Junjie; Zhang, Qunxia; Yin, Ping

    2017-10-23

    RNA editing is a type of post-transcriptional modification that includes nucleotide insertion/deletion or conversion. Different categories of RNA editing have been widely observed in distinct RNAs from divergent organisms. In flowering plants, RNA editing usually alters cytidine to uridine in plastids and mitochondria, playing important roles in various plant developmental processes, including organelle biogenesis, adaptation to environmental changes, and signal transduction. Numerous studies have demonstrated that a number of factors are involved in plant RNA editing, such as pentatricopeptide repeat (PPR) proteins, multiple organelle RNA editing factors (MORF, also known as RIP), organelle RNA recognition motif (ORRM) containing proteins, protoporphyrinogen IX oxidase 1 (PPO1) and organelle zinc finger 1 (OZ1). These factors play diverse roles in plant RNA editing due to their distinct characteristics. In this review, we discuss the functional roles of the individual editing factors and their associations in plant RNA editing.

  14. Report on the 3'rd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011.

    Science.gov (United States)

    Kleinschnitz, Christoph; Meuth, Sven G; Magnus, Tim; Korn, Thomas; Linker, Ralf A

    2012-02-23

    From November 4th- 6th 2011, the 3rd NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. Like in the previous years, the meeting provided an excellent platform for scientific exchange and the presentation of innovative projects for young colleagues in the fields of neurovascular research, neuroinflammation and neurodegeneration. As kick-off to the scientific sessions, Reinhard Hohlfeld, Head of the Institute for Clinical Neuroimmunology in Munich, gave an illustrious overview on the many fascinations of neuroimmunologic research. A particular highlight on the second day of the meeting was the award of the 1'st NEUROWIND e.V. prize for young academics in the field of experimental neurology. This award is posted for young colleagues under the age of 35 with a significant achievement in the field of neurovascular research, neuroinflammation or neurodegeneration and comprises an amount of 20.000 Euro, founded by Merck Serono GmbH, Darmstadt. Germany. The first prize was awarded to Ivana Nikic from Martin Kerschensteiner's group in Munich for her brilliant work on a reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis, published in Nature Medicine in 2011. This first prize award ceremony was a great incentive for the next call for proposals now upcoming in 2012.

  15. Application of statistical shape analysis for the estimation of bone and forensic age using the shapes of the 2nd, 3rd, and 4th cervical vertebrae in a young Japanese population.

    Science.gov (United States)

    Rhee, Chang-Hoon; Shin, Sang Min; Choi, Yong-Seok; Yamaguchi, Tetsutaro; Maki, Koutaro; Kim, Yong-Il; Kim, Seong-Sik; Park, Soo-Byung; Son, Woo-Sung

    2015-12-01

    From computed tomographic images, the dentocentral synchondrosis can be identified in the second cervical vertebra. This can demarcate the border between the odontoid process and the body of the 2nd cervical vertebra and serve as a good model for the prediction of bone and forensic age. Nevertheless, until now, there has been no application of the 2nd cervical vertebra based on the dentocentral synchondrosis. In this study, statistical shape analysis was used to build bone and forensic age estimation regression models. Following the principles of statistical shape analysis and principal components analysis, we used cone-beam computed tomography (CBCT) to evaluate a Japanese population (35 males and 45 females, from 5 to 19 years old). The narrowest prediction intervals among the multivariate regression models were 19.63 for bone age and 2.99 for forensic age. There was no significant difference between form space and shape space in the bone and forensic age estimation models. However, for gender comparison, the bone and forensic age estimation models for males had the higher explanatory power. This study derived an improved objective and quantitative method for bone and forensic age estimation based on only the 2nd, 3rd and 4th cervical vertebral shapes. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  16. A Computational Framework for Vertical Video Editing

    OpenAIRE

    Gandhi, Vineet; Ronfard, Rémi

    2015-01-01

    International audience; Vertical video editing is the process of digitally editing the image within the frame as opposed to horizontal video editing, which arranges the shots along a timeline. Vertical editing can be a time-consuming and error-prone process when using manual key-framing and simple interpolation. In this paper, we present a general framework for automatically computing a variety of cinematically plausible shots from a single input video suitable to the special case of live per...

  17. Human Genome Editing and Ethical Considerations.

    Science.gov (United States)

    Krishan, Kewal; Kanchan, Tanuj; Singh, Bahadur

    2016-04-01

    Editing human germline genes may act as boon in some genetic and other disorders. Recent editing of the genome of the human embryo with the CRISPR/Cas9 editing tool generated a debate amongst top scientists of the world for the ethical considerations regarding its effect on the future generations. It needs to be seen as to what transformation human gene editing brings to humankind in the times to come.

  18. RNA Editing in Pathogenesis of Cancer.

    Science.gov (United States)

    Baysal, Bora E; Sharma, Shraddha; Hashemikhabir, Seyedsasan; Janga, Sarath Chandra

    2017-07-15

    Several adenosine or cytidine deaminase enzymes deaminate transcript sequences in a cell type or environment-dependent manner by a programmed process called RNA editing. RNA editing enzymes catalyze A>I or C>U transcript alterations and have the potential to change protein coding sequences. In this brief review, we highlight some recent work that shows aberrant patterns of RNA editing in cancer. Transcriptome sequencing studies reveal increased or decreased global RNA editing levels depending on the tumor type. Altered RNA editing in cancer cells may provide a selective advantage for tumor growth and resistance to apoptosis. RNA editing may promote cancer by dynamically recoding oncogenic genes, regulating oncogenic gene expression by noncoding RNA and miRNA editing, or by transcriptome scale changes in RNA editing levels that may affect innate immune signaling. Although RNA editing markedly increases complexity of the cancer cell transcriptomes, cancer-specific recoding RNA editing events have yet to be discovered. Epitranscriptomic changes by RNA editing in cancer represent a novel mechanism contributing to sequence diversity independently of DNA mutations. Therefore, RNA editing studies should complement genome sequence data to understand the full impact of nucleic acid sequence alterations in cancer. Cancer Res; 77(14); 3733-9. ©2017 AACR. ©2017 American Association for Cancer Research.

  19. Money and Schools. Fifth Edition

    Science.gov (United States)

    Thompson, David C.; Crampton, Faith E.; Wood, R. Craig

    2012-01-01

    In the new edition of this essential, all-inclusive text, the authors provide more important research for future principals and others enrolled in graduate-level school finance courses. Written in a style that is highly readable, the book offers strong connections to real-world experiences. Readers get both a broad overview of funding concepts and…

  20. Medical writing, revising and editing

    DEFF Research Database (Denmark)

    Pilegaard, Morten

    2006-01-01

    The globalization of science makes medical writing, editing and revision a rapidly growing field of linguistic study and practice. Medical science texts are written according to uniform, general guidelines and medical genres have become highly conventionalized in terms of structure and linguistic...

  1. Editörden

    Directory of Open Access Journals (Sweden)

    Şebnem Korur Fincancı

    2005-08-01

    Full Text Available Değerli Meslektaşlarım, Bu yılın ilk sayısında bir değişiklik gözünüze çarpmış olabilir. Adli Tıp Bülteni artık Türk Tıp Dizini’nde yer almamaktadır ve yer almadığına dair bildirim ilk sayımız basıldıktan sonra elimize ulaşmış olsa da, Adli Tıp Uzmanları Derneğinin başkanları ve dergimizin editörü olarak benim hakkımda yapılmış olan başvuru üzerine hakkımızda yapılan soruşturmalar sırasında, bir başka kişiye verilmiş olan e-posta yanıtından öğrenmiş olmamız dolayısıyla, anılan ibareye geçen sayımızda yer vermemiş idik. Bu süreci paylaşmak gerektiğini düşünüyorum. Türk Tıp Dizini 1997 yılında yaptığımız başvuru sonucu iki taraflı bir sözleşme ile yayın hakkı verdiğimiz kurumsal bir yapılanmadır. Sözleşme 1997 yılında yapılmış olmasına karşın, ilk çıkmaya başladığı 1996 yılından itibaren dergimiz dizinlenmiştir. Sözleşme hükümlerinde, katılım iznini veren taraf olarak sözleşmeyi imzalayan Adli Tıp Bülteni ile ilgili: a\tYayım/yayın haklarını kullanma iznini dergi sahipleri dışında TÜBİTAK’a da verdiğini kabul ettiği, b\tİzin veren taraf olarak süreli yayında söz konusu derginin TÜBİTAK tarafından dizinlendiği belirtilecek ve Türk Tıp Dizini’nin çıkacak olan her sayı için dergisinde bir sayfalık tanıtıya yer vereceği, c\tTürk Tıp Dizini koşullarına uyulmadığı takdirde önce uyarılmak koşulu ile derginin dizinden çıkarılabileceği, d\tİki nüsha tanzim edilen bu sözleşmenin taraflarca imzalandığı, ilk yılın sonunda aksi beyanda bulunulmadığı takdirde ikinci yıl bitimine kadar devam edeceği, e\tSözleşmeden doğan uyuşmazlıklarda Ankara Mahkemeleri ve İcra Dairelerinin yetkili olduğu belirtilmiştir. İlk yılın sonunda aksi beyanda bulunulmadığı takdirde sözleşmenin devam edeceği bildirilmiş olup, Türk Tıp Dizini koşullarına uyulmadığında önce uyar

  2. Diesel Technology: Safety Skills. Teacher Edition [and] Student Edition. Second Edition.

    Science.gov (United States)

    Kellum, Mary

    Teacher and student editions of this document are one in a series of competency-based instructional materials for diesel technology programs. The series aligns with the medium/heavy diesel duty truck task list used by the National Institute for Automotive Service Excellence in the certification of medium/heavy duty truck technicians. Introductory…

  3. Diesel Technology: Steering and Suspension. Second Edition. Teacher Edition [and] Student Edition.

    Science.gov (United States)

    Miller, Roger; Scarberry, Terry; Tesch, Carl; Kellum, Mary

    These teacher and student editions on steering and suspension are part of the diesel mechanics series of instructional materials. The series aligns with the medium/heavy duty truck task list developed by the National Automotive Technicians Education Foundation and used by the National Institute for Automotive Service Excellence in the…

  4. Statistical Physics Approaches to RNA Editing

    Science.gov (United States)

    Bundschuh, Ralf

    2012-02-01

    The central dogma of molecular Biology states that DNA is transcribed base by base into RNA which is in turn translated into proteins. However, some organisms edit their RNA before translation by inserting, deleting, or substituting individual or short stretches of bases. In many instances the mechanisms by which an organism recognizes the positions at which to edit or by which it performs the actual editing are unknown. One model system that stands out by its very high rate of on average one out of 25 bases being edited are the Myxomycetes, a class of slime molds. In this talk we will show how the computational methods and concepts from statistical Physics can be used to analyze DNA and protein sequence data to predict editing sites in these slime molds and to guide experiments that identified previously unknown types of editing as well as the complete set of editing events in the slime mold Physarum polycephalum.

  5. Progress and prospects in plant genome editing.

    Science.gov (United States)

    Yin, Kangquan; Gao, Caixia; Qiu, Jin-Long

    2017-07-31

    The emergence of sequence-specific nucleases that enable genome editing is revolutionizing basic and applied biology. Since the introduction of CRISPR-Cas9, genome editing has become widely used in transformable plants for characterizing gene function and improving traits, mainly by inducing mutations through non-homologous end joining of double-stranded breaks generated by CRISPR-Cas9. However, it would be highly desirable to perform precision gene editing in plants, especially in transformation-recalcitrant species. Recently developed Cas9 variants, novel RNA-guided nucleases and base-editing systems, and DNA-free CRISPR-Cas9 delivery methods now provide great opportunities for plant genome engineering. In this Review Article, we describe the current status of plant genome editing, focusing on newly developed genome editing tools and methods and their potential applications in plants. We also discuss the specific challenges facing plant genome editing, and future prospects.

  6. 3rd International Scientific Conference “Military History of Russia: Problems, Searches, Solutions” Dedicated to the 160th Anniversary of the End of the Crimean War of 1853-1856 (September 23-24, 2016, Volgograd

    Directory of Open Access Journals (Sweden)

    Sergey G. Sidorov

    2016-12-01

    Full Text Available This article provides information about the 3rd International Scientific Conference “Military History of Russia: problems, searches, solutions”, dedicated to the 160th anniversary of the Crimean War of 1853-1856. This conference was held in Volgograd on September 23-24, 2016. The conference was held at the Volgograd State University. Conference was organized by Volgograd State University, Centre for collective use “Military History of Russia”, Centre for the Study of the Battle of Stalingrad, The State Historical and Memorial Museum “Battle of Stalingrad”, State Archive of Volgograd Region, the Volgograd regional Division of the Academy of Military Sciences, the Volgograd Regional Branch of the Russian Military-Historical Society. The conference was informative and representative in its composition: more than 100 representatives of scientific institutions of the Academy of Sciences, universities, archives, museums and libraries from 20 cities of Russia, Azerbaijan, Belarus, Ukraine. 22 doctors of sciences and 40 candidates of sciences were among the participants. Together with respected professors and lecturers the conference was attended by young scientists: assistants, postgraduate students, master students and students. The article analyzes the work of the plenary sessions and 10 sections, the central section of which was “The Crimean War: Russia and the World”. The permanent sections were presented by the reports: on Military History in Antiquity and in the Middle Ages, in New and Recent History; on social protection of the population in wartime; on the military-political conflicts as a threat to the security of society and state; on the international aspects of military conflicts; on the art of war in the methodology of the international “wargame” research; on the results of work of the Centre for the Study of the Battle of Stalingrad.

  7. Editing as a psychological practice.

    Science.gov (United States)

    Beebe, John

    2006-06-01

    The experience of the Jungian analyst in the role of editor of manuscripts by creative colleagues is examined. Historical precedents include Michael Fordham's editorial correspondence with Jung around the latter's synchronicity essay; Jung's handling of manuscripts submitted by Sabina Spielrein to the Jahrbuch für psychoanalytische und psychopathologische Forschungen and various authors to the Zentralblatt für Psychotherapie und ihre Grenzgebiete, and the author's close editing of a paper submitted by Andrew Samuels to the Journal of Analytical Psychology. In addition to mustering an adequate amount of generosity, erudition, and availability, the analytic editor must know how to clarify a psychological argument and to gauge the psychological impact of the written text. Notwithstanding transference/countertransference phenomena that can emerge around issues of competition, envy, and territoriality when author and editor are also fellow-authors working in the same field, the editor needs to be comfortable about serving as the author's selfobject and midwife. From an analytic perspective, although communicating decisions about the best way to put ideas into words can sometimes attract transference to the editor, the more profound transference that analysts experience in the editing situation is toward the text being edited, which helps to motivate donated time spent caring for journal manuscripts.

  8. In search of beneficial coding RNA editing.

    Science.gov (United States)

    Xu, Guixia; Zhang, Jianzhi

    2015-02-01

    RNA editing is a posttranscriptional modification that can lead to a change in the encoded protein sequence of a gene. Although a few cases of mammalian coding RNA editing are known to be functionally important, the vast majority of over 2,000 A-to-I editing sites that have been identified from the coding regions of the human genome are likely nonadaptive, representing tolerable promiscuous targeting of editing enzymes. Finding the potentially tiny fraction of beneficial editing sites from the sea of mostly nearly neutral editing is a difficult but important task. Here, we propose and provide evidence that evolutionarily conserved or "hardwired" residues that experience high-level nonsynonymous RNA editing in a species are enriched with beneficial editing. This simple approach allows the prediction of sites where RNA editing is functionally important. We suggest that priority be given to these candidates in future characterizations of the functional and fitness consequences of RNA editing. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Comparison of Insertional RNA Editing in Myxomycetes

    Science.gov (United States)

    Chen, Cai; Frankhouser, David; Bundschuh, Ralf

    2012-01-01

    RNA editing describes the process in which individual or short stretches of nucleotides in a messenger or structural RNA are inserted, deleted, or substituted. A high level of RNA editing has been observed in the mitochondrial genome of Physarum polycephalum. The most frequent editing type in Physarum is the insertion of individual Cs. RNA editing is extremely accurate in Physarum; however, little is known about its mechanism. Here, we demonstrate how analyzing two organisms from the Myxomycetes, namely Physarum polycephalum and Didymium iridis, allows us to test hypotheses about the editing mechanism that can not be tested from a single organism alone. First, we show that using the recently determined full transcriptome information of Physarum dramatically improves the accuracy of computational editing site prediction in Didymium. We use this approach to predict genes in the mitochondrial genome of Didymium and identify six new edited genes as well as one new gene that appears unedited. Next we investigate sequence conservation in the vicinity of editing sites between the two organisms in order to identify sites that harbor the information for the location of editing sites based on increased conservation. Our results imply that the information contained within only nine or ten nucleotides on either side of the editing site (a distance previously suggested through experiments) is not enough to locate the editing sites. Finally, we show that the codon position bias in C insertional RNA editing of these two organisms is correlated with the selection pressure on the respective genes thereby directly testing an evolutionary theory on the origin of this codon bias. Beyond revealing interesting properties of insertional RNA editing in Myxomycetes, our work suggests possible approaches to be used when finding sequence motifs for any biological process fails. PMID:22383871

  10. Connectivity editing for quad-dominant meshes

    KAUST Repository

    Peng, Chihan

    2013-08-01

    We propose a connectivity editing framework for quad-dominant meshes. In our framework, the user can edit the mesh connectivity to control the location, type, and number of irregular vertices (with more or fewer than four neighbors) and irregular faces (non-quads). We provide a theoretical analysis of the problem, discuss what edits are possible and impossible, and describe how to implement an editing framework that realizes all possible editing operations. In the results, we show example edits and illustrate the advantages and disadvantages of different strategies for quad-dominant mesh design. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  11. New archaeomagnetic data recovered from the study of celtiberic remains from central Spain (Numantia and Ciadueña, 3rd-1st centuries BC). Implications on the fidelity of the Iberian paleointensity database

    Science.gov (United States)

    Osete, M. L.; Chauvin, A.; Catanzariti, G.; Jimeno, A.; Campuzano, S. A.; Benito-Batanero, J. P.; Tabernero-Galán, C.; Roperch, P.

    2016-11-01

    Variations of geomagnetic field in the Iberian Peninsula prior to roman times are poorly constrained. Here we report new archaeomagnetic results from four ceramic collections and two combustion structures recovered in two pre-roman (celtiberic) archaeological sites in central Spain. The studied materials have been dated by archaeological evidences and supported by five radiocarbon dates. Rock magnetic experiments indicate that the characteristic remanent manetization (ChRM) is carried by a low coercivity magnetic phase with Curie temperatures of 530-575 °C, most likely Ti-poor titanomagnetite/titanomaghemite. Archaeointensity determinations were carried out by using the classical Thellier-Thellier protocol including tests and corrections for magnetic anisotropy and cooling rate dependency. Two magnetic behaviours were depicted during the laboratory treatment. Black potsherds and poor heated samples from the kilns, presented two magnetization components, alterations or curved Arai plots and were therefore rejected. In contrast, well heated specimens (red ceramic fragments and well heated samples from the kilns) show one single well defined component of magnetization going through the origin and linear Arai plots providing successful archaeointensity determinations. The effect of anisotropy of the thermoremanent magnetization (ATRM) on paleointensity analysis was systematically investigated obtaining very high ATRM corrections on fine pottery specimens. In some cases, differences between the uncorrected and ATRM corrected paleointensity values reached up to 86 %. The mean intensity values obtained from three selected set of samples were 64.3 ± 5.8 μT; 56.8 ± 3.8 and 56.7 ± 4.6 μT (NUS2, CI2 and CIA, respectively), which contribute to better understand the evolution of the palaeofield intensity in central Iberia during the 3rd-1st centuries BC. The direction of the field at first century BC has also been determined from oriented samples from CIA kilns (D = 357

  12. Operational Transformation In Co-Operative Editing

    Directory of Open Access Journals (Sweden)

    Mandeep Kaur

    2015-08-01

    Full Text Available Cooperative Editing Systems in real-time allows a virtual team to view and edit a shared document at the same time. The document shared must be synchronized in order to ensure consistency for all the participants. This paper describes the Operational Transformation the evolution of its techniques its various applications major issues and achievements. In addition this paper will present working of a platform where two users can edit a code programming file at the same time.

  13. Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

    OpenAIRE

    Shay, Jerry W.; Homma, Noriko; Zhou, Ruyun; Naseer, Muhammad Imran; Chaudhary, Adeel G.; Al-Qahtani, Mohammed; Hirokawa, Nobutaka; Goudarzi, Maryam; Fornace, Albert J.; Baeesa, Saleh; Hussain, Deema; Bangash, Mohammed; Alghamdi, Fahad; Schulten, Hans-Juergen; Carracedo, Angel

    2016-01-01

    Table of contents O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabo...

  14. Therapeutic Gene Editing Safety and Specificity.

    Science.gov (United States)

    Lux, Christopher T; Scharenberg, Andrew M

    2017-10-01

    Therapeutic gene editing is significant for medical advancement. Safety is intricately linked to the specificity of the editing tools used to cut at precise genomic targets. Improvements can be achieved by thoughtful design of nucleases and repair templates, analysis of off-target editing, and careful utilization of viral vectors. Advancements in DNA repair mechanisms and development of new generations of tools improve targeting of specific sequences while minimizing risks. It is important to plot a safe course for future clinical trials. This article reviews safety and specificity for therapeutic gene editing to spur dialogue and advancement. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Graph edit distance from spectral seriation.

    Science.gov (United States)

    Robles-Kelly, Antonio; Hancock, Edwin R

    2005-03-01

    This paper is concerned with computing graph edit distance. One of the criticisms that can be leveled at existing methods for computing graph edit distance is that they lack some of the formality and rigor of the computation of string edit distance. Hence, our aim is to convert graphs to string sequences so that string matching techniques can be used. To do this, we use a graph spectral seriation method to convert the adjacency matrix into a string or sequence order. We show how the serial ordering can be established using the leading eigenvector of the graph adjacency matrix. We pose the problem of graph-matching as a maximum a posteriori probability (MAP) alignment of the seriation sequences for pairs of graphs. This treatment leads to an expression in which the edit cost is the negative logarithm of the a posteriori sequence alignment probability. We compute the edit distance by finding the sequence of string edit operations which minimizes the cost of the path traversing the edit lattice. The edit costs are determined by the components of the leading eigenvectors of the adjacency matrix and by the edge densities of the graphs being matched. We demonstrate the utility of the edit distance on a number of graph clustering problems.

  16. Fuel Cell Handbook, Fourth Edition

    Energy Technology Data Exchange (ETDEWEB)

    Stauffer, D.B; Hirschenhofer, J.H.; Klett, M.G.; Engleman, R.R.

    1998-11-01

    Robust progress has been made in fuel cell technology since the previous edition of the Fuel Cell Handbook was published in January 1994. This Handbook provides a foundation in fuel cells for persons wanting a better understanding of the technology, its benefits, and the systems issues that influence its application. Trends in technology are discussed, including next-generation concepts that promise ultra high efficiency and low cost, while providing exceptionally clean power plant systems. Section 1 summarizes fuel cell progress since the last edition and includes existing power plant nameplate data. Section 2 addresses the thermodynamics of fuel cells to provide an understanding of fuel cell operation at two levels (basic and advanced). Sections 3 through 6 describe the four major fuel cell types and their performance based on cell operating conditions. The section on polymer electrolyte membrane fuel cells has been added to reflect their emergence as a significant fuel cell technology. Phosphoric acid, molten carbonate, and solid oxide fuel cell technology description sections have been updated from the previous edition. New information indicates that manufacturers have stayed with proven cell designs, focusing instead on advancing the system surrounding the fuel cell to lower life cycle costs. Section 7, Fuel Cell Systems, has been significantly revised to characterize near-term and next-generation fuel cell power plant systems at a conceptual level of detail. Section 8 provides examples of practical fuel cell system calculations. A list of fuel cell URLs is included in the Appendix. A new index assists the reader in locating specific information quickly.

  17. RNAEditor: easy detection of RNA editing events and the introduction of editing islands.

    Science.gov (United States)

    John, David; Weirick, Tyler; Dimmeler, Stefanie; Uchida, Shizuka

    2017-11-01

    RNA editing of adenosine residues to inosine ('A-to-I editing') is the most common RNA modification event detectible with RNA sequencing (RNA-seq). While not directly detectable, inosine is read by next-generation sequencers as guanine. Therefore, mapping RNA-seq reads to their corresponding reference genome can detect potential editing events by identifying 'A-to-G' conversions. However, one must exercise caution when searching for editing sites, as A-to-G conversions also arise from sequencing errors as well as mutations. To address these complexities, several algorithms and software products have been developed to accurately identify editing events. Here, we survey currently available methods to analyze RNA editing events and introduce a new easy-to-use bioinformatics tool 'RNAEditor' for the detection of RNA editing events. During the development of RNAEditor, we noticed editing often happened in clusters, which we named 'editing islands'. We developed a clustering algorithm to find editing islands and included it in RNAEditor. RNAEditor is freely available at http://rnaeditor.uni-frankfurt.de. We anticipate that RNAEditor will provide biologists with an easy-to-use tool for studying RNA editing events and the newly defined editing islands. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. GPU Computing Gems Emerald Edition

    CERN Document Server

    Hwu, Wen-mei W

    2011-01-01

    ".the perfect companion to Programming Massively Parallel Processors by Hwu & Kirk." -Nicolas Pinto, Research Scientist at Harvard & MIT, NVIDIA Fellow 2009-2010 Graphics processing units (GPUs) can do much more than render graphics. Scientists and researchers increasingly look to GPUs to improve the efficiency and performance of computationally-intensive experiments across a range of disciplines. GPU Computing Gems: Emerald Edition brings their techniques to you, showcasing GPU-based solutions including: Black hole simulations with CUDA GPU-accelerated computation and interactive display of

  19. The Aldine Edition of Aristotle's De Sensu

    DEFF Research Database (Denmark)

    Bloch, David Kristian

    2006-01-01

    This small article examines the quality of and the textual foundation for the først printed edition ever of Aristotle's De Sensu et Sensibilibus, that is, Aldus Manutius' (1497).......This small article examines the quality of and the textual foundation for the først printed edition ever of Aristotle's De Sensu et Sensibilibus, that is, Aldus Manutius' (1497)....

  20. Applications of genome editing in insects

    Science.gov (United States)

    Insect genome editing was first reported 1991 in Drosophila melanogaster but the technology used was not portable to other species. Not until the recent development of facile, engineered DNA endonuclease systems has gene editing become widely available to insect scientists. Most applications in inse...

  1. Sex Differences in Cognitive Abilities. Fourth Edition

    Science.gov (United States)

    Halpern, Diane F.

    2011-01-01

    The fourth edition of "Sex Differences in Cognitive Abilities" critically examines the breadth of research on this complex and controversial topic, with the principal aim of helping the reader to understand where sex differences are found--and where they are not. Since the publication of the third edition, there have been many exciting and…

  2. Accounting for Independent Schools. Second Edition.

    Science.gov (United States)

    National Association of Independent Schools, Boston, MA.

    This is a thoroughly revised edition of the 1969 publication, "Accounting for Independent Schools," a guide that attempted to codify basic accounting principles and practices for specific application to independent schools. The focus of the second edition is more on refining practices than on initiating them, and more on extending the managerial…

  3. Novel modes of RNA editing in mitochondria.

    Science.gov (United States)

    Moreira, Sandrine; Valach, Matus; Aoulad-Aissa, Mohamed; Otto, Christian; Burger, Gertraud

    2016-06-02

    Gene structure and expression in diplonemid mitochondria are unparalleled. Genes are fragmented in pieces (modules) that are separately transcribed, followed by the joining of module transcripts to contiguous RNAs. Some instances of unique uridine insertion RNA editing at module boundaries were noted, but the extent and potential occurrence of other editing types remained unknown. Comparative analysis of deep transcriptome and genome data from Diplonema papillatum mitochondria reveals ∼220 post-transcriptional insertions of uridines, but no insertions of other nucleotides nor deletions. In addition, we detect in total 114 substitutions of cytosine by uridine and adenosine by inosine, amassed into unusually compact clusters. Inosines in transcripts were confirmed experimentally. This is the first report of adenosine-to-inosine editing of mRNAs and ribosomal RNAs in mitochondria. In mRNAs, editing causes mostly amino-acid additions and non-synonymous substitutions; in ribosomal RNAs, it permits formation of canonical secondary structures. Two extensively edited transcripts were compared across four diplonemids. The pattern of uridine-insertion editing is strictly conserved, whereas substitution editing has diverged dramatically, but still rendering diplonemid proteins more similar to other eukaryotic orthologs. We posit that RNA editing not only compensates but also sustains, or even accelerates, ultra-rapid evolution of genome structure and sequence in diplonemid mitochondria. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  4. Investigating RNA editing factors from trypanosome mitochondria.

    Science.gov (United States)

    Aphasizheva, Inna; Zhang, Liye; Aphasizhev, Ruslan

    2016-09-01

    Mitochondrial U-insertion/deletion mRNA editing is carried out by two principal multiprotein assemblies, enzymatic RNA editing core (RECC) and RNA editing substrate binding (RESC) complexes, and a plethora of auxiliary factors. An integral part of mitochondrial gene expression, editing receives inputs from primary mRNA and gRNA precursor processing pathways, and generates substrates for mRNA polyadenylation and translation. Although nearly all RECC-embedded enzymes have been implicated in specific editing reactions, the majority of proteins that populate the RESC are also essential for generating edited mRNAs. However, lack of recognizable motifs in RESC subunits limits the prowess of bioinformatics in guiding biochemical experiments and elucidating their specific biological functions. In this chapter, we describe a generic workflow for investigating mitochondrial mRNA editing in Trypanosoma brucei and focus on several methods that proved instrumental is assigning definitive functions to editing factors lacking known signature sequences. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. A comparison of low IQ scores from the Reynolds Intellectual Assessment Scales and the Wechsler Adult Intelligence Scale-Third Edition.

    Science.gov (United States)

    Umphress, Thomas B

    2008-06-01

    Twenty people with suspected intellectual disability took the Reynolds Intellectual Assessment Scales (RIAS; C. R. Reynolds & R. W. Kamphaus, 1998) and the Wechsler Adult Intelligence Scale-3rd Edition (WAIS-III; D. Wechsler, 1997) to see if the 2 IQ tests produced comparable results. A t test showed that the RIAS Composite Intelligence Index scores were significantly higher than WAIS-III Full Scale IQ scores at the alpha level of .01. There was a significant difference between the RIAS Nonverbal Intelligence and WAIS-III Performance Scale, but there was no significant difference between the RIAS Verbal Intelligence Index and the WAIS-III Verbal Scale IQ. The results raise questions concerning test selection for diagnosing intellectual disability and the use of the correlation statistic for comparing intelligence tests.

  6. On Mesh Editing, Manifold Learning, and Diffusion Wavelets

    Science.gov (United States)

    Rustamov, R. M.

    We spell out a formal equivalence between the naive Laplacian editing and semi-supervised learning by bi-Laplacian Regularized Least Squares. This allows us to write the solution to Laplacian mesh editing in a ‘closed’ form, based on which we introduce the Generalized Linear Editing (GLE). GLE has both naive Laplacian editing and gradient based editing as special cases. GLE allows using diffusion wavelets for mesh editing. We present preliminary experiments, and shortly discuss connections to segmentation.

  7. Ultra-high pitch chest computed tomography at 70 kVp tube voltage in an anthropomorphic pediatric phantom and non-sedated pediatric patients: Initial experience with 3(rd) generation dual-source CT.

    Science.gov (United States)

    Hagelstein, Claudia; Henzler, Thomas; Haubenreisser, Holger; Meyer, Mathias; Sudarski, Sonja; Schoenberg, Stefan O; Neff, K Wolfgang; Weis, Meike

    2016-12-01

    Minimizing radiation dose while at the same time preserving image quality is of particular importance in pediatric chest CT. Very recently, CT imaging with a tube voltage of 70 kVp has become clinically available. However, image noise is inversely proportional to the tube voltage. We aimed to investigate radiation dose and image quality of pediatric chest CT performed at 70 kVp in an anthropomorphic pediatric phantom as well as in clinical patients. An anthropomorphic pediatric phantom, which resembles a one-year-old child in physiognomy, was scanned on the 3(rd) generation dual-source CT (DSCT) system at 70 kVp and 80 kVp and a fixed ultra low tube-current of 8 mAs to solely evaluate the impact of lowering tube voltage. After the phantom measurements, 18 pediatric patients (mean 29.5 months; range 1-91 months; 21 examinations) underwent 3.2 high-pitch chest CT on the same DSCT system at 70 kVp tube voltage without any sedation. Radiation dose and presence of motion artifacts was compared to a retrospectively identified patient cohort examined at 80 kVp on a 16-slice single-source-CT (SSCT; n=15; 14/15 with sedation; mean 30.7 months; range 0-96 months; pitch=1.5) or on a 2(nd) generation DSCT without any sedation (n=6; mean 32.8 months; range 4-61 months; pitch=3.2). Radiation dose in the phantom scans was reduced by approximately 40% when using a tube voltage of 70 kVp instead of 80 kVp. In the pediatric patient group examined at 70 kVp age-specific effective dose (ED; mean 0.5±0.2 mSv) was significantly lower when compared to the retrospective cohort scanned at 80 kVp on the 16-slice-SSCT (mean ED: 1.0±0.3 mSv; p<0.0001) and also considerably lower when compared to the cohort scanned at 80 kVp on the 2(nd) generation DSCT (mean ED: 0.9±0.5 mSv). None of the prospective, sedation-free CT examinations showed any motion artifacts whereas 13/15 examinations of the retrospective patient cohort scanned at 80 kVp with a pitch of 1.5 showed motion artifacts. 3.2 high

  8. In vitro apolipoprotein B mRNA editing: identification of a 27S editing complex.

    Science.gov (United States)

    Smith, H C; Kuo, S R; Backus, J W; Harris, S G; Sparks, C E; Sparks, J D

    1991-01-01

    Specific apolipoprotein B (apoB) mRNA editing can be performed in vitro on apoB RNA substrates. Native gels and glycerol gradient sedimentation have been used to determine the physical properties of the in vitro editing activity in rat liver cytosolic S100 extracts. ApoB RNA substrates were progressively assembled as 27S complexes for 3 hr with similar kinetics as seen for the accumulation of edited RNA. Assembly was not observed on RNAs from apoB deletion constructs that did not support editing. The 27S complex contained both edited and unedited RNA sequences. Inhibition of 27S complex assembly by vanadyl-ribonucleoside complexes was accompanied by inhibition of editing. Based on these data, we propose that the 27S complex is the in vitro "editosome," A "mooring sequence" model for RNA recognition and editosome assembly has been proposed involving RNA sequences flanking the edited nucleotide. Images PMID:1996349

  9. Genetic Architectures of Quantitative Variation in RNA Editing Pathways.

    Science.gov (United States)

    Gu, Tongjun; Gatti, Daniel M; Srivastava, Anuj; Snyder, Elizabeth M; Raghupathy, Narayanan; Simecek, Petr; Svenson, Karen L; Dotu, Ivan; Chuang, Jeffrey H; Keller, Mark P; Attie, Alan D; Braun, Robert E; Churchill, Gary A

    2016-02-01

    RNA editing refers to post-transcriptional processes that alter the base sequence of RNA. Recently, hundreds of new RNA editing targets have been reported. However, the mechanisms that determine the specificity and degree of editing are not well understood. We examined quantitative variation of site-specific editing in a genetically diverse multiparent population, Diversity Outbred mice, and mapped polymorphic loci that alter editing ratios globally for C-to-U editing and at specific sites for A-to-I editing. An allelic series in the C-to-U editing enzyme Apobec1 influences the editing efficiency of Apob and 58 additional C-to-U editing targets. We identified 49 A-to-I editing sites with polymorphisms in the edited transcript that alter editing efficiency. In contrast to the shared genetic control of C-to-U editing, most of the variable A-to-I editing sites were determined by local nucleotide polymorphisms in proximity to the editing site in the RNA secondary structure. Our results indicate that RNA editing is a quantitative trait subject to genetic variation and that evolutionary constraints have given rise to distinct genetic architectures in the two canonical types of RNA editing. Copyright © 2016 by the Genetics Society of America.

  10. Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome.

    Science.gov (United States)

    Daniel, Chammiran; Widmark, Albin; Rigardt, Ditte; Öhman, Marie

    2017-10-23

    Adenosine to inosine (A-to-I) RNA editing has been shown to be an essential event that plays a significant role in neuronal function, as well as innate immunity, in mammals. It requires a structure that is largely double-stranded for catalysis but little is known about what determines editing efficiency and specificity in vivo. We have previously shown that some editing sites require adjacent long stem loop structures acting as editing inducer elements (EIEs) for efficient editing. The glutamate receptor subunit A2 is edited at the Q/R site in almost 100% of all transcripts. We show that efficient editing at the Q/R site requires an EIE in the downstream intron, separated by an internal loop. Also, other efficiently edited sites are flanked by conserved, highly structured EIEs and we propose that this is a general requisite for efficient editing, while sites with low levels of editing lack EIEs. This phenomenon is not limited to mRNA, as non-coding primary miRNAs also use EIEs to recruit ADAR to specific sites. We propose a model where two regions of dsRNA are required for efficient editing: first, an RNA stem that recruits ADAR and increases the local concentration of the enzyme, then a shorter, less stable duplex that is ideal for efficient and specific catalysis. This discovery changes the way we define and determine a substrate for A-to-I editing. This will be important in the discovery of novel editing sites, as well as explaining cases of altered editing in relation to disease.

  11. Fuel Cell Handbook, Fifth Edition

    Energy Technology Data Exchange (ETDEWEB)

    Energy and Environmental Solutions

    2000-10-31

    Progress continues in fuel cell technology since the previous edition of the Fuel Cell Handbook was published in November 1998. Uppermost, polymer electrolyte fuel cells, molten carbonate fuel cells, and solid oxide fuel cells have been demonstrated at commercial size in power plants. The previously demonstrated phosphoric acid fuel cells have entered the marketplace with more than 220 power plants delivered. Highlighting this commercial entry, the phosphoric acid power plant fleet has demonstrated 95+% availability and several units have passed 40,000 hours of operation. One unit has operated over 49,000 hours. Early expectations of very low emissions and relatively high efficiencies have been met in power plants with each type of fuel cell. Fuel flexibility has been demonstrated using natural gas, propane, landfill gas, anaerobic digester gas, military logistic fuels, and coal gas, greatly expanding market opportunities. Transportation markets worldwide have shown remarkable interest in fuel cells; nearly every major vehicle manufacturer in the U.S., Europe, and the Far East is supporting development. This Handbook provides a foundation in fuel cells for persons wanting a better understanding of the technology, its benefits, and the systems issues that influence its application. Trends in technology are discussed, including next-generation concepts that promise ultrahigh efficiency and low cost, while providing exceptionally clean power plant systems. Section 1 summarizes fuel cell progress since the last edition and includes existing power plant nameplate data. Section 2 addresses the thermodynamics of fuel cells to provide an understanding of fuel cell operation at two levels (basic and advanced). Sections 3 through 8 describe the six major fuel cell types and their performance based on cell operating conditions. Alkaline and intermediate solid state fuel cells were added to this edition of the Handbook. New information indicates that manufacturers have stayed

  12. Genome edited animals: Learning from GM crops?

    Science.gov (United States)

    Bruce, Ann

    2017-06-01

    Genome editing of livestock is poised to become commercial reality, yet questions remain as to appropriate regulation, potential impact on the industry sector and public acceptability of products. This paper looks at how genome editing of livestock has attempted to learn some of the lessons from commercialisation of GM crops, and takes a systemic approach to explore some of the complexity and ambiguity in incorporating genome edited animals in a food production system. Current applications of genome editing are considered, viewed from the perspective of past technological applications. The question of what is genome editing, and can it be considered natural is examined. The implications of regulation on development of different sectors of livestock production systems are studied, with a particular focus on the veterinary sector. From an EU perspective, regulation of genome edited animals, although not necessarily the same as for GM crops, is advocated from a number of different perspectives. This paper aims to open up new avenues of research on genome edited animals, extending from the current primary focus on science and regulation, to engage with a wider-range of food system actors.

  13. RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications.

    Science.gov (United States)

    Han, Leng; Liang, Han

    2016-03-01

    We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.

  14. LabVIEW 8 student edition

    CERN Document Server

    Bishop, Robert H

    2007-01-01

    For courses in Measurement and Instrumentation, Electrical Engineering lab, and Physics and Chemistry lab. This revised printing has been updated to include new LabVIEW 8.2 Student Edition. National Instruments' LabVIEW is the defacto industry standard for test, measurement, and automation software solutions. With the Student Edition of LabVIEW, students can design graphical programming solutions to their classroom problems and laboratory experiments with software that delivers the graphical programming capabilites of the LabVIEW professional version. . The Student Edition is also compatible with all National Instruments data acquisition and instrument control hardware. Note: The LabVIEW Student Edition is available to students, faculty, and staff for personal educational use only. It is not intended for research, institutional, or commercial use. For more information about these licensing options, please visit the National Instruments website at (http:www.ni.com/academic/)

  15. Editing soft shadows in a digital photograph.

    Science.gov (United States)

    Mohan, Ankit; Tumblin, Jack; Choudhury, Prasun

    2007-01-01

    This technique for modeling, editing, and rendering shadow edges in a photograph or a synthetic image lets users separate the shadow from the rest of the image and make arbitrary adjustments to its position, sharpness, and intensity.

  16. Gene Editing: Regulatory and Translation to Clinic.

    Science.gov (United States)

    Ando, Dale; Meyer, Kathleen

    2017-10-01

    The clinical application and regulatory strategy of genome editing for ex vivo cell therapy is derived from the intersection of two fields of study: viral vector gene therapy trials; and clinical trials with ex vivo purification and engraftment of CD34+ hematopoietic stem cells, T cells, and tumor cell vaccines. This article covers the regulatory and translational preclinical activities needed for a genome editing clinical trial modifying hematopoietic stem cells and the genesis of this current strategy based on previous clinical trials using genome-edited T cells. The SB-728 zinc finger nuclease platform is discussed because this is the most clinically advanced genome editing technology. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. The NMC Horizon Report: 2014 Library Edition

    NARCIS (Netherlands)

    Johnson, L; Adams Becker, S.; Estrada, V.; Freeman, A.; van den Brekel, Guus

    2014-01-01

    The NMC Horizon Report: 2014 Library Edition, examines key trends, significant challenges, and emerging technologies for their potential impact on academic and research libraries worldwide. While there are many local factors affecting libraries, there are also issues that transcend regional

  18. Specification Editing and Discovery Assistant Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The project will prototype a specification editing and discovery tool (SPEEDY) for C/C++ that will assist software developers with modular formal verification tasks...

  19. RNA editing generates cellular subsets with diverse sequence within populations.

    Science.gov (United States)

    Harjanto, Dewi; Papamarkou, Theodore; Oates, Chris J; Rayon-Estrada, Violeta; Papavasiliou, F Nina; Papavasiliou, Anastasia

    2016-07-15

    RNA editing is a mutational mechanism that specifically alters the nucleotide content in transcribed RNA. However, editing rates vary widely, and could result from equivalent editing amongst individual cells, or represent an average of variable editing within a population. Here we present a hierarchical Bayesian model that quantifies the variance of editing rates at specific sites using RNA-seq data from both single cells, and a cognate bulk sample to distinguish between these two possibilities. The model predicts high variance for specific edited sites in murine macrophages and dendritic cells, findings that we validated experimentally by using targeted amplification of specific editable transcripts from single cells. The model also predicts changes in variance in editing rates for specific sites in dendritic cells during the course of LPS stimulation. Our data demonstrate substantial variance in editing signatures amongst single cells, supporting the notion that RNA editing generates diversity within cellular populations.

  20. Biomass conversion plants in Germany. EEG amendment modifies the market. Results of trend:research study Biogas in Germany up to 2020 (3rd edition); Biogasanlagen in Deutschland. EEG-Novelle veraendert Markt. Ergebnisse der trend:research-Studie Biogas in Deutschland bis 2030 (3. Auflage)

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2012-05-15

    Due to the amendment of the Renewable Energy Act, the demands on operators of biogas plants increase. At the same time the existing bonus system is abolished. Essentially, the increased construction of plants is performed in agricultural small plants with a capacity below 75 kW. The implementation of a market premium results in a new segment in the area of commercialization of electricity from biogas at the electricity market EEX in Leipzig (Federal Republic of Germany).

  1. Looking forward to genetically edited fruit crops.

    Science.gov (United States)

    Nagamangala Kanchiswamy, Chidananda; Sargent, Daniel James; Velasco, Riccardo; Maffei, Massimo E; Malnoy, Mickael

    2015-02-01

    The availability of genome sequences for many fruit crops has redefined the boundaries of genetic engineering and genetically modified (GM) crop plants. However commercialization of GM crops is hindered by numerous regulatory and social hurdles. Here, we focus on recently developed genome-editing tools for fruit crop improvement and their importance from the consumer perspective. Challenges and opportunities for the deployment of new genome-editing tools for fruit plants are also discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. Non-GMO genetically edited crop plants.

    Science.gov (United States)

    Kanchiswamy, Chidananda Nagamangala; Malnoy, Mickael; Velasco, Riccardo; Kim, Jin-Soo; Viola, Roberto

    2015-09-01

    Direct delivery of purified Cas9 protein with guide RNA into plant cells, as opposed to plasmid-mediated delivery, displays high efficiency and reduced off-target effects. Following regeneration from edited cells, the ensuing plant is also likely to bypass genetically modified organism (GMO) legislation as the genome editing complex is degraded in the recipient cells. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Therapeutic gene editing: delivery and regulatory perspectives.

    Science.gov (United States)

    Shim, Gayong; Kim, Dongyoon; Park, Gyu Thae; Jin, Hyerim; Suh, Soo-Kyung; Oh, Yu-Kyoung

    2017-06-01

    Gene-editing technology is an emerging therapeutic modality for manipulating the eukaryotic genome by using target-sequence-specific engineered nucleases. Because of the exceptional advantages that gene-editing technology offers in facilitating the accurate correction of sequences in a genome, gene editing-based therapy is being aggressively developed as a next-generation therapeutic approach to treat a wide range of diseases. However, strategies for precise engineering and delivery of gene-editing nucleases, including zinc finger nucleases, transcription activator-like effector nuclease, and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-associated nuclease Cas9), present major obstacles to the development of gene-editing therapies, as with other gene-targeting therapeutics. Currently, viral and non-viral vectors are being studied for the delivery of these nucleases into cells in the form of DNA, mRNA, or proteins. Clinical trials are already ongoing, and in vivo studies are actively investigating the applicability of CRISPR/Cas9 techniques. However, the concept of correcting the genome poses major concerns from a regulatory perspective, especially in terms of safety. This review addresses current research trends and delivery strategies for gene editing-based therapeutics in non-clinical and clinical settings and considers the associated regulatory issues.

  4. On the evaluation of segmentation editing tools

    Science.gov (United States)

    Heckel, Frank; Moltz, Jan H.; Meine, Hans; Geisler, Benjamin; Kießling, Andreas; D’Anastasi, Melvin; dos Santos, Daniel Pinto; Theruvath, Ashok Joseph; Hahn, Horst K.

    2014-01-01

    Abstract. Efficient segmentation editing tools are important components in the segmentation process, as no automatic methods exist that always generate sufficient results. Evaluating segmentation editing algorithms is challenging, because their quality depends on the user’s subjective impression. So far, no established methods for an objective, comprehensive evaluation of such tools exist and, particularly, intermediate segmentation results are not taken into account. We discuss the evaluation of editing algorithms in the context of tumor segmentation in computed tomography. We propose a rating scheme to qualitatively measure the accuracy and efficiency of editing tools in user studies. In order to objectively summarize the overall quality, we propose two scores based on the subjective rating and the quantified segmentation quality over time. Finally, a simulation-based evaluation approach is discussed, which allows a more reproducible evaluation without the need for human input. This automated evaluation complements user studies, allowing a more convincing evaluation, particularly during development, where frequent user studies are not possible. The proposed methods have been used to evaluate two dedicated editing algorithms on 131 representative tumor segmentations. We show how the comparison of editing algorithms benefits from the proposed methods. Our results also show the correlation of the suggested quality score with the qualitative ratings. PMID:26158063

  5. The commercialization of genome-editing technologies.

    Science.gov (United States)

    Brinegar, Katelyn; K Yetisen, Ali; Choi, Sun; Vallillo, Emily; Ruiz-Esparza, Guillermo U; Prabhakar, Anand M; Khademhosseini, Ali; Yun, Seok-Hyun

    2017-11-01

    The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from basic research to translational medicine. In our analyses, we evaluated the patent landscape of gene-editing technologies and found that in comparison to earlier gene-editing techniques, CRISPR has gained significant traction and this has established dominance. Although most of the gene-editing technologies originated from the industry, CRISPR has been pioneered by academic research institutions. The spinout of CRISPR biotechnology companies from academic institutions demonstrates a shift in entrepreneurship strategies that were previously led by the industry. These academic institutions, and their subsequent companies, are competing to generate comprehensive intellectual property portfolios to rapidly commercialize CRISPR products. Our analysis shows that the emergence of CRISPR has resulted in a fivefold increase in genome-editing bioenterprise investment over the last year. This entrepreneurial movement has spurred a global biotechnology revolution in the realization of novel gene-editing technologies. This global shift in bioenterprise will continue to grow as the demand for personalized medicine, genetically modified crops and environmentally sustainable biofuels increases. However, the monopolization of intellectual property, negative public perception of genetic engineering and ambiguous regulatory policies may limit the growth of these market segments.

  6. Genome editing with engineered nucleases in plants.

    Science.gov (United States)

    Osakabe, Yuriko; Osakabe, Keishi

    2015-03-01

    Numerous examples of successful 'genome editing' now exist. Genome editing uses engineered nucleases as powerful tools to target specific DNA sequences to edit genes precisely in the genomes of both model and crop plants, as well as a variety of other organisms. The DNA-binding domains of zinc finger (ZF) proteins were the first to be used as genome editing tools, in the form of designed ZF nucleases (ZFNs). More recently, transcription activator-like effector nucleases (TALENs), as well as the clustered regularly interspaced short palindromic repeats/Cas9 (CRISPR/Cas9) system, which utilizes RNA-DNA interactions, have proved useful. A key step in genome editing is the generation of a double-stranded DNA break that is specific to the target gene. This is achieved by custom-designed endonucleases, which enable site-directed mutagenesis via a non-homologous end-joining (NHEJ) repair pathway and/or gene targeting via homologous recombination (HR) to occur efficiently at specific sites in the genome. This review provides an overview of recent advances in genome editing technologies in plants, and discusses how these can provide insights into current plant molecular biology research and molecular breeding technology. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  7. Applications of genome editing in insects.

    Science.gov (United States)

    Reid, William; O'Brochta, David A

    2016-02-01

    Insect genome editing was first reported 1991 in Drosophila melanogaster but the technology used was not portable to other species. Not until the recent development of facile, engineered DNA endonuclease systems has gene editing become widely available to insect scientists. Most applications in insects to date have been technical in nature but this is rapidly changing. Functional genomics and genetics-based insect control efforts will be major beneficiaries of the application of contemporary gene editing technologies. Engineered endonucleases like Cas9 make it possible to create powerful and effective gene drive systems that could be used to reduce or even eradicate specific insect populations. 'Best practices' for using Cas9-based editing are beginning to emerge making it easier and more effective to design and use but gene editing technologies still require traditional means of delivery in order to introduce them into somatic and germ cells of insects-microinjection of developing embryos. This constrains the use of these technologies by insect scientists. Insects created using editing technologies challenge existing governmental regulatory structures designed to manage genetically modified organisms. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing

    Science.gov (United States)

    Simpson, Rachel M.; Bruno, Andrew E.; Bard, Jonathan E.; Buck, Michael J.

    2016-01-01

    Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequential use of noncoding template RNAs called guide RNAs. The majority of steady-state mitochondrial mRNAs are partially edited and often contain regions of mis-editing, termed junctions, whose role is unclear. Here, we report a novel method for sequencing entire populations of pre-edited partially edited, and fully edited RNAs and analyzing editing characteristics across populations using a new bioinformatics tool, the Trypanosome RNA Editing Alignment Tool (TREAT). Using TREAT, we examined populations of two transcripts, RPS12 and ND7-5′, in wild-type Trypanosoma brucei. We provide evidence that the majority of partially edited sequences contain junctions, that intrinsic pause sites arise during the progression of editing, and that the mechanisms that mediate pausing in the generation of canonical fully edited sequences are distinct from those that mediate the ends of junction regions. Furthermore, we identify alternatively edited sequences that constitute plausible alternative open reading frames and identify substantial variability in the 5′ UTRs of both canonical and alternatively edited sequences. This work is the first to use high-throughput sequencing to examine full-length sequences of whole populations of partially edited transcripts. Our method is highly applicable to current questions in the RNA editing field, including defining mechanisms of action for editing factors and identifying potential alternatively edited sequences. PMID:26908922

  9. High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing.

    Science.gov (United States)

    Simpson, Rachel M; Bruno, Andrew E; Bard, Jonathan E; Buck, Michael J; Read, Laurie K

    2016-05-01

    Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequential use of noncoding template RNAs called guide RNAs. The majority of steady-state mitochondrial mRNAs are partially edited and often contain regions of mis-editing, termed junctions, whose role is unclear. Here, we report a novel method for sequencing entire populations of pre-edited partially edited, and fully edited RNAs and analyzing editing characteristics across populations using a new bioinformatics tool, the Trypanosome RNA Editing Alignment Tool (TREAT). Using TREAT, we examined populations of two transcripts, RPS12 and ND7-5', in wild-typeTrypanosoma brucei We provide evidence that the majority of partially edited sequences contain junctions, that intrinsic pause sites arise during the progression of editing, and that the mechanisms that mediate pausing in the generation of canonical fully edited sequences are distinct from those that mediate the ends of junction regions. Furthermore, we identify alternatively edited sequences that constitute plausible alternative open reading frames and identify substantial variability in the 5' UTRs of both canonical and alternatively edited sequences. This work is the first to use high-throughput sequencing to examine full-length sequences of whole populations of partially edited transcripts. Our method is highly applicable to current questions in the RNA editing field, including defining mechanisms of action for editing factors and identifying potential alternatively edited sequences. © 2016 Simpson et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  10. [Textual research on the edition of WU Kun's books].

    Science.gov (United States)

    Wang, Xu-Guang; Lu, Xiang

    2013-03-01

    WU Kun is a famous physician of the Xin'an School. He wrote a 6-volume Yi fang kao (Textual Research on Recipes) in 1584, a 24-volume Wu zhu su wen (Wu's Annotation of Plain Questions) in 1594, a 6-volume Zhen fang liu ji (Six Collections of Acupuncture and Prescription) in 1618 block-printed and funded by CHENG Biao, and a 2-volume Mai yu (Language of Pulse) with writing date unknown. For Yi fang kao, there were 4 editions, including Ming-dynasty block-printed edition, Japanese and Korean block-printed edition, old hand-copied edition and modern printing edition. For Wu zhu su wen, there were 5 editions, Ming-Qing-dynasty block-printed edition, Japanese block-printed edition, old hand-copied edition, photocopy and modern edition. For Zhen fang liu ji, there were Ming-dynasty block-printed edition, hand-copied edition, photocopy and modern edition. Mai yu always was printed together with Yi fang kao, and its editions were same as those of Yi fang kao, except some modern printing edition with Mai yu excluded.

  11. Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing

    OpenAIRE

    Penn, Andrew C; Balik, Ales; Greger, Ingo H.

    2012-01-01

    Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in metazoa. In addition to wide-spread editing in non-coding regions protein recoding by RNA editing allows for fine tuning of protein function. Functional consequences are only known for some editing sites and the combinatorial effect between multiple sites (functional epistasis) is currently unclear. Similarly, the interplay between RNA editing and splicing, which impacts on...

  12. Book Review: New Perspectives on Technical Editing

    Science.gov (United States)

    Murphy, A. J. (Ed.); Sterken, Christiaan

    2012-08-01

    New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

  13. Designed nucleases for targeted genome editing.

    Science.gov (United States)

    Lee, Junwon; Chung, Jae-Hee; Kim, Ho Min; Kim, Dong-Wook; Kim, Hyongbum

    2016-02-01

    Targeted genome-editing technology using designed nucleases has been evolving rapidly, and its applications are widely expanding in research, medicine and biotechnology. Using this genome-modifying technology, researchers can precisely and efficiently insert, remove or change specific sequences in various cultured cells, micro-organisms, animals and plants. This genome editing is based on the generation of double-strand breaks (DSBs), repair of which modifies the genome through nonhomologous end-joining (NHEJ) or homology-directed repair (HDR). In addition, designed nickase-induced generation of single-strand breaks can also lead to precise genome editing through HDR, albeit at relatively lower efficiencies than that induced by nucleases. Three kinds of designed nucleases have been used for targeted DSB formation: zinc-finger nucleases, transcription activator-like effector nucleases, and RNA-guided engineered nucleases derived from the bacterial clustered regularly interspaced short palindromic repeat (CRISPR)-Cas (CRISPR-associated) system. A growing number of researchers are using genome-editing technologies, which have become more accessible and affordable since the discovery and adaptation of CRISPR-Cas9. Here, the repair mechanism and outcomes of DSBs are reviewed and the three types of designed nucleases are discussed with the hope that such understanding will facilitate applications to genome editing. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  14. The First Mediterranean Seminar on Science Writing, Editing and Publishing, Sarajevo, December 2-3, 2016.

    Science.gov (United States)

    Masic, Izet; Donev, Doncho; Sinanovic, Osman; Jakovljevic, Miro; Zerem, Enver; Milosevic, Dejan B; Gajovic, Srecko; Gasparyan, Armen Yuri; Sokolovic, Sekib; Salkic, Nermin; Uzunovic, Selma; Dobric, Silva; Kurti, Floreta; Begic, Edin; Kurtcehajic, Admir

    2016-12-01

    The First Mediterranean Seminar on Science Writing, Editing & Publishing (SWEP 2016) was held in Sarajevo, Bosnia & Herzegovina from 2nd to 3rd December 2016. It was organized by Academy of Medical Sciences of Bosnia and Herzegovina, running concurrent sessions as part of its Annual Meeting titled " "Days of AMNuBiH - Theory and Practice in Science Communication and Scientometrics". Hotel Bosnia in the city centre was the chosen venue. On the first day, nineteen presentations on various issues of science writing and publication ethics were delivered by speakers from Croatia, Serbia, Macedonia, Albania, Bosnia & Herzegovina and the UK (Asim Kurjak, Milivoj Boranić, Doncho Donev, Osman Sinanović, Miro Jakovljević, Enver Zerem, Dejan Milošević, Silva Dobrić, Srećko Gajović, Izet Mašić, Armen Yuri Gasparyan, Šekib Sokolović, Nermin Salkić, Selma Uzunović, Admir Kurtčehajić, Edin Begić and Floreta Kurti). Each presentation had a take-home message for novice and seasoned authors, encountering numerous problems in non-Anglophone research environment. Lecturers, who were internationally recognized editors of regional journals, generously shared their experience of adhering to the best ethical guidance. Elegant presentations by Srećko Gajović (Editor-in-Chief of the Croatian Medical Journal) and Armen Yuri Gasparyan (past Chief Editor of the European Science Editing) showcased their accomplishments that strengthened ties between authors from all over the world. Gasparyan reflected on educational resources of editorial associations, such as the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE), and called not just to declare the adherence to, but also to enforce their ethical guidance in daily practice. Editors of Medical Archives, Croatian Medica Journal, Vojnosanitetski Pregled, Psychiatria Danubina, Acta Informatica Medica, Materia Socio-Medica, The Donald School Journal of Ultrasound in Obstretics

  15. Quantum Field Theory, Revised Edition

    Science.gov (United States)

    Mandl, F.; Shaw, G.

    1994-01-01

    Quantum Field Theory Revised Edition F. Mandl and G. Shaw, Department of Theoretical Physics, The Schuster Laboratory, The University, Manchester, UK When this book first appeared in 1984, only a handful of W± and Z° bosons had been observed and the experimental investigation of high energy electro-weak interactions was in its infancy. Nowadays, W± bosons and especially Z° bosons can be produced by the thousand and the study of their properties is a precise science. We have revised the text of the later chapters to incorporate these developments and discuss their implications. We have also taken this opportunity to update the references throughout and to make some improvements in the treatment of dimen-sional regularization. Finally, we have corrected some minor errors and are grateful to various people for pointing these out. This book is designed as a short and simple introduction to quantum field theory for students beginning research in theoretical and experimental physics. The three main objectives are to explain the basic physics and formalism of quantum field theory, to make the reader fully proficient in theory calculations using Feynman diagrams, and to introduce the reader to gauge theories, which play such a central role in elementary particle physics. The theory is applied to quantum electrodynamics (QED), where quantum field theory had its early triumphs, and to weak interactions where the standard electro-weak theory has had many impressive successes. The treatment is based on the canonical quantization method, because readers will be familiar with this, because it brings out lucidly the connection between invariance and conservation laws, and because it leads directly to the Feynman diagram techniques which are so important in many branches of physics. In order to help inexperienced research students grasp the meaning of the theory and learn to handle it confidently, the mathematical formalism is developed from first principles, its physical

  16. Introduction to nuclear science, second edition

    CERN Document Server

    Bryan, Jeff C.

    2013-01-01

    This book was written to provide students who have limited backgrounds in the physical sciences and math with an accessible textbook on nuclear science. Expanding on the foundation of the bestselling first edition, Introduction to Nuclear Science, Second Edition provides a clear and complete introduction to nuclear chemistry and physics, from basic concepts to nuclear power and medical applications. Incorporating suggestions from professors using this book for their courses, the author has created a new text that is approximately 60 percent larger and more comprehensive and flexible than the first.New to This Edition: Thorough review of nuclear forensics, radiology, gamma cameras, and decay through proton or neutron emission More detailed explanations of the necessary mathematics A chapter on dosimetry of radiation fields Expanded discussion of applications, introduced earlier in the text More in-depth coverage of nuclear reactors, including a new chapter examining more reactor types, their safety systems,...

  17. Ethical and regulatory aspects of genome editing.

    Science.gov (United States)

    Kohn, Donald B; Porteus, Matthew H; Scharenberg, Andrew M

    2016-05-26

    Gene editing is a rapidly developing area of biotechnology in which the nucleotide sequence of the genome of living cells is precisely changed. The use of genome-editing technologies to modify various types of blood cells, including hematopoietic stem cells, has emerged as an important field of therapeutic development for hematopoietic disease. Although these technologies offer the potential for generation of transformative therapies for patients suffering from myriad disorders of hematopoiesis, their application for therapeutic modification of primary human cells is still in its infancy. Consequently, development of ethical and regulatory frameworks that ensure their safe and effective use is an increasingly important consideration. Here, we review a number of issues that have the potential to impact the clinical implementation of genome-editing technologies, and suggest paths forward for resolving them such that new therapies can be safely and rapidly translated to the clinic. © 2016 by The American Society of Hematology.

  18. JICST Thesaurus : Compilation of the 1987 Edition

    Science.gov (United States)

    Saito, Kazuo; Sakagami, Yasuhiko; Totsuka, Takayuki; Okano, Hiroyuki; Shirayama, Kunihiko; Gomibuchi, Takeshi

    We had requests such as enlargement of terms to be covered in the Thesaurus, description of term history and so on through the questionnaires to JOIS users specifically conducted on the occasion of preparing 1987 edition of JICST Thesaurus. Based on them the following measures were taken : addition of new terms by referring natural words stored in JICST database, addition of some Chinese characters used for it, addition of priority data among synonyms and others, and improvement of term relations by using English translated Japanese keywords. How the Thesaurus was edited, and measures against problems associated with editing are described. Necessity of the routine maintenance and subjects to be solved from now on are also described.

  19. RNA Editing and Its Molecular Mechanism in Plant Organelles

    Science.gov (United States)

    Ichinose, Mizuho; Sugita, Mamoru

    2016-01-01

    RNA editing by cytidine (C) to uridine (U) conversions is widespread in plant mitochondria and chloroplasts. In some plant taxa, “reverse” U-to-C editing also occurs. However, to date, no instance of RNA editing has yet been reported in green algae and the complex thalloid liverworts. RNA editing may have evolved in early land plants 450 million years ago. However, in some plant species, including the liverwort, Marchantia polymorpha, editing may have been lost during evolution. Most RNA editing events can restore the evolutionarily conserved amino acid residues in mRNAs or create translation start and stop codons. Therefore, RNA editing is an essential process to maintain genetic information at the RNA level. Individual RNA editing sites are recognized by plant-specific pentatricopeptide repeat (PPR) proteins that are encoded in the nuclear genome. These PPR proteins are characterized by repeat elements that bind specifically to RNA sequences upstream of target editing sites. In flowering plants, non-PPR proteins also participate in multiple RNA editing events as auxiliary factors. C-to-U editing can be explained by cytidine deamination. The proteins discovered to date are important factors for RNA editing but a bona fide RNA editing enzyme has yet to be identified. PMID:28025543

  20. RNA Editing and Its Molecular Mechanism in Plant Organelles.

    Science.gov (United States)

    Ichinose, Mizuho; Sugita, Mamoru

    2016-12-23

    RNA editing by cytidine (C) to uridine (U) conversions is widespread in plant mitochondria and chloroplasts. In some plant taxa, "reverse" U-to-C editing also occurs. However, to date, no instance of RNA editing has yet been reported in green algae and the complex thalloid liverworts. RNA editing may have evolved in early land plants 450 million years ago. However, in some plant species, including the liverwort, Marchantia polymorpha, editing may have been lost during evolution. Most RNA editing events can restore the evolutionarily conserved amino acid residues in mRNAs or create translation start and stop codons. Therefore, RNA editing is an essential process to maintain genetic information at the RNA level. Individual RNA editing sites are recognized by plant-specific pentatricopeptide repeat (PPR) proteins that are encoded in the nuclear genome. These PPR proteins are characterized by repeat elements that bind specifically to RNA sequences upstream of target editing sites. In flowering plants, non-PPR proteins also participate in multiple RNA editing events as auxiliary factors. C-to-U editing can be explained by cytidine deamination. The proteins discovered to date are important factors for RNA editing but a bona fide RNA editing enzyme has yet to be identified.

  1. Spatial Hadamard encoding of J-edited spectroscopy using slice-selective editing pulses.

    Science.gov (United States)

    Chan, Kimberly L; Oeltzschner, Georg; Schär, Michael; Barker, Peter B; Edden, Richard A E

    2017-05-01

    A new approach for simultaneous dual-voxel J-difference spectral editing is described, which uses spatially selective spectral-editing pulses and Hadamard encoding. A theoretical framework for spatial Hadamard editing and reconstruction for parallel acquisition (SHERPA) was developed, applying gradient pulses during the frequency-selective editing pulses. Spectral simulations were performed for either one (gamma-aminobutyric acid, GABA) or two molecules (glutathione and lactate) simultaneously detected in two voxels. The method was tested in a two-compartment GABA phantom, and finally applied to the left and right hemispheres of 10 normal control subjects, scanned at 3 T. SHERPA was successfully implemented at 3 T and gave results in close agreement with conventional MEGA-PRESS scans in both the phantom and in vivo experiments. Simulations for GABA editing for (3 cm)3 voxels in the left and right hemispheres suggest that both editing efficiency losses and contamination between voxels are about 2%. Compared with conventional single-voxel single-metabolite J-difference editing, two- or fourfold acceleration is possible without significant loss of SNR using the SHERPA method. Unlike some other dual-voxel methods, the method can be used with single-channel receiver coils, and there is no SNR loss due to unfavorable receive-coil geometry factors. Copyright © 2017 John Wiley & Sons, Ltd.

  2. Introductory Nuclear Physics, 2nd Edition

    Science.gov (United States)

    Wong, Samuel S. M.

    1998-08-01

    A comprehensive, unified treatment of present-day nuclear physics-the fresh edition of a classic text/reference. "A fine and thoroughly up-to-date textbook on nuclear physics . . . most welcome." -Physics Today (on the First Edition). What sets Introductory Nuclear Physics apart from other books on the subject is its presentation of nuclear physics as an integral part of modern physics. Placing the discipline within a broad historical and scientific context, it makes important connections to other fields such as elementary particle physics and astrophysics. Now fully revised and updated, this Second Edition explores the changing directions in nuclear physics, emphasizing new developments and current research-from superdeformation to quark-gluon plasma. Author Samuel S.M. Wong preserves those areas that established the First Edition as a standard text in university physics departments, focusing on what is exciting about the discipline and providing a concise, thorough, and accessible treatment of the fundamental aspects of nuclear properties. In this new edition, Professor Wong: * Includes a chapter on heavy-ion reactions-from high-spin states to quark-gluon plasma * Adds a new chapter on nuclear astrophysics * Relates observed nuclear properties to the underlying nuclear interaction and the symmetry principles governing subatomic particles * Regroups material and appendices to make the text easier to use * Lists Internet links to essential databases and research projects * Features end-of-chapter exercises using real-world data. Introductory Nuclear Physics, Second Edition is an ideal text for courses in nuclear physics at the senior undergraduate or first-year graduate level. It is also an important resource for scientists and engineers working with nuclei, for astrophysicists and particle physicists, and for anyone wishing to learn more about trends in the field.

  3. Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.

    Science.gov (United States)

    Vallecillo-Viejo, Isabel C; Liscovitch-Brauer, Noa; Montiel-Gonzalez, Maria Fernanda; Eisenberg, Eli; Rosenthal, Joshua J C

    2017-11-03

    Site-directed RNA editing (SDRE) is a general strategy for making targeted base changes in RNA molecules. Although the approach is relatively new, several groups, including our own, have been working on its development. The basic strategy has been to couple the catalytic domain of an adenosine (A) to inosine (I) RNA editing enzyme to a guide RNA that is used for targeting. Although highly efficient on-target editing has been reported, off-target events have not been rigorously quantified. In this report we target premature termination codons (PTCs) in messages encoding both a fluorescent reporter protein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein transiently transfected into human epithelial cells. We demonstrate that while on-target editing is efficient, off-target editing is extensive, both within the targeted message and across the entire transcriptome of the transfected cells. By redirecting the editing enzymes from the cytoplasm to the nucleus, off-target editing is reduced without compromising the on-target editing efficiency. The addition of the E488Q mutation to the editing enzymes, a common strategy for increasing on-target editing efficiency, causes a tremendous increase in off-target editing. These results underscore the need to reduce promiscuity in current approaches to SDRE.

  4. Transportation Energy Data Book, Edition 19

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.C.

    1999-09-01

    The Transportation Energy Data Book: Edition 19 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Transportation Technologies in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (http://www-cta.ornl.gov/data/tedb.htm).

  5. Current and future editing reagent delivery systems for plant genome editing.

    Science.gov (United States)

    Ran, Yidong; Liang, Zhen; Gao, Caixia

    2017-05-01

    Many genome editing tools have been developed and new ones are anticipated; some have been extensively applied in plant genetics, biotechnology and breeding, especially the CRISPR/Cas9 system. These technologies have opened up a new era for crop improvement due to their precise editing of user-specified sequences related to agronomic traits. In this review, we will focus on an update of recent developments in the methodologies of editing reagent delivery, and consider the pros and cons of current delivery systems. Finally, we will reflect on possible future directions.

  6. Shielded Metal Arc Welding and Carbon Arc Cutting--Air. Teacher Edition [and] Student Edition [and] Student Workbook. Third Edition.

    Science.gov (United States)

    Harper, Eddie; Knapp, John

    This document contains the teacher and student texts and student workbook for a secondary-level course in shielded metal arc welding (SMAW) and carbon arc cutting that consists of units on the following topics: SMAW safety; SMAW equipment, applications, and techniques; hardfacing; and carbon arc cutting--air. The teacher edition includes the…

  7. Genes (including RNA editing information) - RMG | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available t tested T: transcribed N: not transcribed Editing site Editing site N: not transcribed Previous reports on ...editing sites Previous reports on editing sites Strand Strand S: sense A: antisense exon1 start Start positi

  8. RNA Editing and Drug Discovery for Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Wei-Hsuan Huang

    2013-01-01

    Full Text Available RNA editing is vital to provide the RNA and protein complexity to regulate the gene expression. Correct RNA editing maintains the cell function and organism development. Imbalance of the RNA editing machinery may lead to diseases and cancers. Recently, RNA editing has been recognized as a target for drug discovery although few studies targeting RNA editing for disease and cancer therapy were reported in the field of natural products. Therefore, RNA editing may be a potential target for therapeutic natural products. In this review, we provide a literature overview of the biological functions of RNA editing on gene expression, diseases, cancers, and drugs. The bioinformatics resources of RNA editing were also summarized.

  9. Direct Visual Editing of Node Attributes in Graphs

    Directory of Open Access Journals (Sweden)

    Christian Eichner

    2016-10-01

    Full Text Available There are many expressive visualization techniques for analyzing graphs. Yet, there is only little research on how existing visual representations can be employed to support data editing. An increasingly relevant task when working with graphs is the editing of node attributes. We propose an integrated visualize-and-edit approach to editing attribute values via direct interaction with the visual representation. The visualize part is based on node-link diagrams paired with attribute-dependent layouts. The edit part is as easy as moving nodes via drag-and-drop gestures. We present dedicated interaction techniques for editing quantitative as well as qualitative attribute data values. The benefit of our novel integrated approach is that one can directly edit the data while the visualization constantly provides feedback on the implications of the data modifications. Preliminary user feedback indicates that our integrated approach can be a useful complement to standard non-visual editing via external tools.

  10. An RNA editing fingerprint of cancer stem cell reprogramming

    National Research Council Canada - National Science Library

    Crews, Leslie A; Jiang, Qingfei; Zipeto, Maria A; Lazzari, Elisa; Court, Angela C; Ali, Shawn; Barrett, Christian L; Frazer, Kelly A; Jamieson, Catriona Hm

    2015-01-01

    .... The objectives of this study were to validate RNA editing of a subset of cancer stem cell-associated transcripts, and to develop a quantitative RNA editing fingerprint assay for rapid detection...

  11. Editörden Veda

    Directory of Open Access Journals (Sweden)

    Serpil Salaçin

    2000-04-01

    ştirenler. Kendine göre oıtak düşünce ve yürek ürünü olan dergiyi asılsız ve haksız yorumlayanlar. Ama tüm zorlukların üstesinden gelindiğini düşünüyorum. Bu nedenle benim kişisel olarak baştan beri üstlenmeyi düşündüğüm görevimin tamamlandığını düşünüyorum. Aşağıda bir kaç gün önce derneğimiz başkanlığına gönderdiğim görevden affım ile ilgili mektubu bu derneğin üyeleri olarak sizlerin de öğrenmeye hakkınız olduğunu düşünerek sizlerle paylaşmak istiyorum. Adli Tıp Uzmanları Derneği Başkanlığına, Sayın Prof. Dr. Gürsel Çetin, 26.03.2001 Derneğimizin kuruluşundan bu yana meslektaşlarımızın özverileri ile üretilenlere katkıda bulunmak hepimiz için görev olarak algılanıp yerine getirilmeye çalışıldı. Bu etkinlikler içinde bu alanın bilimsel üretimlerini paylaşabileceği, danışmanlı olarak çalışabilecek bir derginin oluşturulması fikri de derneğimizin bir etkinliğinde sizin de bildiğiniz koşullarda ortaya atıldı. Benimsendi. Bu üretimin gerçekleştirilmesinde görev verilenlerden de biri de bendim. Çıkarılacak derginin editörlük görevini bana vermiştiniz. Bana duyulan güvene ve verilmiş olan bu göreve teşekkür ediyorum. Adli Tıp Bülteni, ismi ile eldeki sınırlı olanaklarla rengi, kapağı, amblemi, formatı ile bir grup özverili arkadaşımızla birlikte doğdu. (ISSN 1300-865X kaydını aldı. Ben bu görevi bir meslek misyonu olarak gerçekleştirmeye çalıştım. Ulusal ve uluslar arası danışma kurulunun oluşturulmasında edindiğim uluslararası ilişkileri devreye sokarak bu kurulların zenginleştirilmesine çalıştım. Birlikte çalıştığımız arkadaşlarımızın her birinin özverileri ile dergi yazım kuralları, gelen makalelerin kaydı, danışmanlara gönderilmesi, danışman ve yazar arasındaki yazışmaların gerçekleştirilmesi, her sayının içeriği ve makale dışı yazı düzenlemeleri, sîzlerin de yakından bildiği bir

  12. [The Korean and Japanese editions of the Korean medical book-Dongyi Baojian].

    Science.gov (United States)

    Kim, Nam-I

    2011-03-01

    From 1613, Dongyi Baojian (written by Huh Joon) has been published in more than 30 editions in Korea, China and Japan. There are 13 kinds of editions in Korea-movable type edition in the Kuichou year; block printed Lingying edition in the Jihai year; the first Lingying edition in Jiaxu year; the edited Lingying edition in the Jiaxu year and the Wanying reprint edition in the Jiaxu year. There are 2 kinds of editions in Japan-the first edition in the Xiangbao period and the reprint edition in the Kuanzheng period.

  13. Dynamic landscape and regulation of RNA editing in mammals.

    Science.gov (United States)

    Tan, Meng How; Li, Qin; Shanmugam, Raghuvaran; Piskol, Robert; Kohler, Jennefer; Young, Amy N; Liu, Kaiwen Ivy; Zhang, Rui; Ramaswami, Gokul; Ariyoshi, Kentaro; Gupte, Ankita; Keegan, Liam P; George, Cyril X; Ramu, Avinash; Huang, Ni; Pollina, Elizabeth A; Leeman, Dena S; Rustighi, Alessandra; Goh, Y P Sharon; Chawla, Ajay; Del Sal, Giannino; Peltz, Gary; Brunet, Anne; Conrad, Donald F; Samuel, Charles E; O'Connell, Mary A; Walkley, Carl R; Nishikura, Kazuko; Li, Jin Billy

    2017-10-11

    Adenosine-to-inosine (A-to-I) RNA editing is a conserved post-transcriptional mechanism mediated by ADAR enzymes that diversifies the transcriptome by altering selected nucleotides in RNA molecules. Although many editing sites have recently been discovered, the extent to which most sites are edited and how the editing is regulated in different biological contexts are not fully understood. Here we report dynamic spatiotemporal patterns and new regulators of RNA editing, discovered through an extensive profiling of A-to-I RNA editing in 8,551 human samples (representing 53 body sites from 552 individuals) from the Genotype-Tissue Expression (GTEx) project and in hundreds of other primate and mouse samples. We show that editing levels in non-repetitive coding regions vary more between tissues than editing levels in repetitive regions. Globally, ADAR1 is the primary editor of repetitive sites and ADAR2 is the primary editor of non-repetitive coding sites, whereas the catalytically inactive ADAR3 predominantly acts as an inhibitor of editing. Cross-species analysis of RNA editing in several tissues revealed that species, rather than tissue type, is the primary determinant of editing levels, suggesting stronger cis-directed regulation of RNA editing for most sites, although the small set of conserved coding sites is under stronger trans-regulation. In addition, we curated an extensive set of ADAR1 and ADAR2 targets and showed that many editing sites display distinct tissue-specific regulation by the ADAR enzymes in vivo. Further analysis of the GTEx data revealed several potential regulators of editing, such as AIMP2, which reduces editing in muscles by enhancing the degradation of the ADAR proteins. Collectively, our work provides insights into the complex cis- and trans-regulation of A-to-I editing.

  14. 45 CFR 73.735-705 - Writing and editing.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Writing and editing. 73.735-705 Section 73.735-705... Outside Activities § 73.735-705 Writing and editing. (a) Employees are encouraged to engage in outside writing and editing whether or not done for compensation, when such activity is not otherwise prohibited...

  15. Soil Carbon Sequestration and the Greenhouse Effect (2nd Edition)

    Science.gov (United States)

    This volume is a second edition of the book “Soil Carbon Sequestration and The Greenhouse Effect”. The first edition was published in 2001 as SSSA Special Publ. #57. The present edition is an update of the concepts, processes, properties, practices and the supporting data. All chapters are new co...

  16. Human Resources Administration: A School-Based Perspective. Fourth Edition

    Science.gov (United States)

    Smith, Richard

    2009-01-01

    Enhanced and updated, this Fourth Edition of Richard E. Smith's highly successful text examines the growing role of the principal in planning, hiring, staff development, supervision, and other human resource functions. The Fourth Edition includes new sections on ethics, induction, and the role of the mentor teacher. This edition also introduces…

  17. Human germline gene editing: Recommendations of ESHG and ESHRE

    NARCIS (Netherlands)

    de Wert, Guido; Pennings, Guido; Clarke, Angus; Eichenlaub-Ritter, Ursula; van El, Carla G.; Forzano, Francesca; Goddijn, Mariëtte; Heindryckx, Björn; Howard, Heidi C.; Radojkovic, Dragica; Rial-Sebbag, Emmanuelle; Tarlatzis, Basil C.; Cornel, Martina C.

    2018-01-01

    Technological developments in gene editing raise high expectations for clinical applications, first of all for somatic gene editing but in theory also for germline gene editing (GLGE). GLGE is currently not allowed in many countries. This makes clinical applications in these countries impossible

  18. Alternative Splicing of STAT3 Is Affected by RNA Editing.

    Science.gov (United States)

    Goldberg, Lior; Abutbul-Amitai, Mor; Paret, Gideon; Nevo-Caspi, Yael

    2017-05-01

    A-to-I RNA editing, carried out by adenosine deaminase acting on RNA (ADAR) enzymes, is an epigenetic phenomenon of posttranscriptional modifications on pre-mRNA. RNA editing in intronic sequences may influence alternative splicing of flanking exons. We have previously shown that conditions that induce editing result in elevated expression of signal transducer and activator of transcription 3 (STAT3), preferentially the alternatively-spliced STAT3β isoform. Mechanisms regulating alternative splicing of STAT3 have not been elucidated. STAT3 undergoes A-to-I RNA editing in an intron residing in proximity to the alternatively spliced exon. We hypothesized that RNA editing plays a role in regulating alternative splicing toward STAT3β. In this study we extend our observation connecting RNA editing to the preferential induction of STAT3β expression. We study the involvement of ADAR1 in STAT3 editing and reveal the connection between editing and alternative splicing of STAT3. Deferoaxamine treatment caused the induction in STAT3 RNA editing and STAT3β expression. Silencing ADAR1 caused a decrease in STAT3 editing and expression with a preferential decrease in STAT3β. Cells transfected with a mutated minigene showed preferential splicing toward the STAT3β transcript. Editing in the STAT3 intron is performed by ADAR1 and affects STAT3 alternative splicing. These results suggest that RNA editing is one of the molecular mechanisms regulating the expression of STAT3β.

  19. Adenosine to Inosine editing frequency controlled by splicing efficiency.

    Science.gov (United States)

    Licht, Konstantin; Kapoor, Utkarsh; Mayrhofer, Elisa; Jantsch, Michael F

    2016-07-27

    Alternative splicing and adenosine to inosine (A to I) RNA-editing are major factors leading to co- and post-transcriptional modification of genetic information. Both, A to I editing and splicing occur in the nucleus. As editing sites are frequently defined by exon-intron basepairing, mRNA splicing efficiency should affect editing levels. Moreover, splicing rates affect nuclear retention and will therefore also influence the exposure of pre-mRNAs to the editing-competent nuclear environment. Here, we systematically test the influence of splice rates on RNA-editing using reporter genes but also endogenous substrates. We demonstrate for the first time that the extent of editing is controlled by splicing kinetics when editing is guided by intronic elements. In contrast, editing sites that are exclusively defined by exonic structures are almost unaffected by the splicing efficiency of nearby introns. In addition, we show that editing levels in pre- and mature mRNAs do not match. This phenomenon can in part be explained by the editing state of an RNA influencing its splicing rate but also by the binding of the editing enzyme ADAR that interferes with splicing. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  20. Genome-wide identification of RNA editing in hepatocellular carcinoma.

    Science.gov (United States)

    Kang, Lin; Liu, Xiaoqiao; Gong, Zhoulin; Zheng, Hancheng; Wang, Jun; Li, Yingrui; Yang, Huanming; Hardwick, James; Dai, Hongyue; Poon, Ronnie T P; Lee, Nikki P; Mao, Mao; Peng, Zhiyu; Chen, Ronghua

    2015-02-01

    We did whole-transcriptome sequencing and whole-genome sequencing on nine pairs of Hepatocellular carcinoma (HCC) tumors and matched adjacent tissues to identify RNA editing events. We identified mean 26,982 editing sites with mean 89.5% canonical A→G edits in each sample using an improved bioinformatics pipeline. The editing rate was significantly higher in tumors than adjacent normal tissues. Comparing the difference between tumor and normal tissues of each patient, we found 7 non-synonymous tissue specific editing events including 4 tumor-specific edits and 3 normal-specific edits in the coding region, as well as 292 edits varying in editing degree. The significant expression changes of 150 genes associated with RNA editing were found in tumors, with 3 of the 4 most significant genes being cancer related. Our results show that editing might be related to higher gene expression. These findings indicate that RNA editing modification may play an important role in the development of HCC. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Editing modifies the GABA(A) receptor subunit alpha3

    DEFF Research Database (Denmark)

    Ohlson, Johan; Pedersen, Jakob Skou; Haussler, David

    2007-01-01

    Adenosine to inosine (A-to-I) pre-mRNA editing by the ADAR enzyme family has the potential to increase the variety of the proteome. This editing by adenosine deamination is essential in mammals for a functional brain. To detect novel substrates for A-to-I editing we have used an experimental meth...

  2. School Leadership: Handbook for Excellence. Second Edition.

    Science.gov (United States)

    Smith, Stuart C., Ed.; Piele, Philip K., Ed.

    Recognizing the importance of good leadership to the achievement of educational excellence, the second edition of this handbook synthesizes a large body of school leadership literature and explores the subject from three perspectives: the person, the structure, and the skills. Part I examines characteristics of today's educational leaders;…

  3. The NMC Horizon Report: 2013 Museum Edition

    Science.gov (United States)

    Johnson, L.; Adams Becker, S.; Freeman, A.

    2013-01-01

    The "NMC Horizon Report: 2013 Museum Edition," is a co-production with the Marcus Institute for Digital Education in the Arts (MIDEA), and examines six emerging technologies for their potential impact on and use in education and interpretation within the museum environment: BYOD (Bring Your Own Device), crowdsourcing, electronic…

  4. The Landscape of Qualitative Research. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna, Ed.

    2007-01-01

    This book, the first volume of the paperback versions of the "The SAGE Handbook of Qualitative Research, Third Edition," takes a look at the field from a broadly theoretical perspective, and is composed of the Handbook's Parts I ("Locating the Field"), II ("Major Paradigms and Perspectives"), and VI ("The Future of Qualitative Research"). "The…

  5. Handbook of Qualitative Research. Second Edition.

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna S., Ed.

    This handbook's second edition represents the state of the art for the theory and practice of qualitative inquiry. It features eight new topics, including autoethnography, critical race theory, applied ethnography, queer theory, and "testimonio"every chapter in the handbook has been thoroughly revised and updated. The book…

  6. Collecting and Interpreting Qualitative Materials. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna, Ed.

    2007-01-01

    This book is the third volume of the paperback versions of "The SAGE Handbook of Qualitative Research, Third Edition." This portion of the handbook considers the tasks of collecting, analyzing, and interpreting empirical materials, and comprises the Handbook's Parts IV ("Methods of Collecting and Analyzing Empirical Materials") and V ("The Art and…

  7. School Law: Cases and Concepts. Seventh Edition.

    Science.gov (United States)

    LaMorte, Michael W.

    This book examines the sizable body of school law that outlines legally defensible decisions. A substantial part of it contains edited, reported, and verbatim decisions. Historical perspective is provided, as well as specific case and statutory law. Chapter 1 discusses sources of law for educators, state school board policies, attorneys-general…

  8. Regression Analysis by Example. 5th Edition

    Science.gov (United States)

    Chatterjee, Samprit; Hadi, Ali S.

    2012-01-01

    Regression analysis is a conceptually simple method for investigating relationships among variables. Carrying out a successful application of regression analysis, however, requires a balance of theoretical results, empirical rules, and subjective judgment. "Regression Analysis by Example, Fifth Edition" has been expanded and thoroughly…

  9. The Technique of Television Production. Revised Edition.

    Science.gov (United States)

    Millerson, Gerald

    In discussing the technical aspects of television production, this book covers both equipment and techniques used in these areas: camera, lighting, sound, settings, and make-up. Composition of images according to camera movement, placement of subjects, editing, and aural composition are also covered. Steps in the technical planning of a telecast…

  10. Genome Editing in Sugarcane: Challenges ahead

    Directory of Open Access Journals (Sweden)

    Chakravarthi Mohan

    2016-10-01

    Full Text Available Genome editing opens new and unique opportunities for researchers to enhance crop production. Until 2013, the zinc finger nucleases (ZFNs and transcription activator-like effector nucleases (TALENs were the key tools used for genome editing applications. The advent of RNA-guided engineered nucleases - the type II clustered regularly interspaced short palindromic repeat (CRISPR/Cas9 (CRISPR-associated system from Streptococcus pyogenes holds great potential since it is simple, effective and more versatile than ZFNs and TALENs. CRISPR/Cas9 system has already been successfully employed in several crop plants. Use of these techniques is in its infant stage in sugarcane. Jung and Altpeter (2016 have reported TALEN mediated approach for the first time to reduce lignin content in sugarcane to make it amenable for biofuel production. This is so far the only report describing genome editing in sugarcane. Large genome size, polyploidy, low transformation efficiency, transgene silencing and lack of high throughput screening techniques are certainly great challenges for genome editing in sugarcane which would be discussed in detail in this review.

  11. CRISPR-Cas9 gene editing

    NARCIS (Netherlands)

    Oude Blenke, Erik; Evers, Martijn J.W.; Mastrobattista, Enrico; Oost, van der John

    2016-01-01

    The CRISPR-Cas9 gene editing system has taken the biomedical science field by storm, initiating rumors about future Nobel Prizes and heating up a fierce patent war, but also making significant scientific impact. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with

  12. Precision genome editing in the CRISPR era.

    Science.gov (United States)

    Salsman, Jayme; Dellaire, Graham

    2017-04-01

    With the introduction of precision genome editing using CRISPR-Cas9 technology, we have entered a new era of genetic engineering and gene therapy. With RNA-guided endonucleases, such as Cas9, it is possible to engineer DNA double strand breaks (DSB) at specific genomic loci. DSB repair by the error-prone non-homologous end-joining (NHEJ) pathway can disrupt a target gene by generating insertions and deletions. Alternatively, Cas9-mediated DSBs can be repaired by homology-directed repair (HDR) using an homologous DNA repair template, thus allowing precise gene editing by incorporating genetic changes into the repair template. HDR can introduce gene sequences for protein epitope tags, delete genes, make point mutations, or alter enhancer and promoter activities. In anticipation of adapting this technology for gene therapy in human somatic cells, much focus has been placed on increasing the fidelity of CRISPR-Cas9 and increasing HDR efficiency to improve precision genome editing. In this review, we will discuss applications of CRISPR technology for gene inactivation and genome editing with a focus on approaches to enhancing CRISPR-Cas9-mediated HDR for the generation of cell and animal models, and conclude with a discussion of recent advances and challenges towards the application of this technology for gene therapy in humans.

  13. Researching Society and Culture. Third Edition

    Science.gov (United States)

    Seale, Clive, Ed.

    2012-01-01

    Clear, coherent and trusted, this book is the perfect guide to the main social research methods in use today. The much anticipated Third Edition of Clive Seale's bestselling title further expands its coverage to provide an authoritative introduction to all of the social research methods used to analyze qualitative and quantitative data. Written by…

  14. A DESCRIPTIVE INDONESIAN GRAMMAR--PRELIMINARY EDITION.

    Science.gov (United States)

    DYEN, ISIDORE

    THIS PRELIMINARY EDITION COMPRISES A DESCRIPTIVE GRAMMAR OF INDONESIAN (BAHASA INDONESIA), THE OFFICIAL LANGUAGE OF THE REPUBLIC OF INDONESIA. THE THREE SECTIONS--PHONOLOGY, SYNTAX, AND MORPHOLOGY--PRESENT A COMPREHENSIVE LINGUISTIC ANALYSIS OF INDONESIAN, WITH OCCASIONAL CONTRASTIVE REFERENCE TO MALAY, JAVANESE, SUNDANESE, AND SUMATRAN. THIS…

  15. ISEE : An Intuitive Sound Editing Environment

    NARCIS (Netherlands)

    Vertegaal, R.P.H.; Bonis, E.

    1994-01-01

    This article presents ISEE, an intuitive sound editing environment, as a general sound synthesis model based on expert auditory perception and cognition of musical instruments. It discusses the backgrounds of current synthesizer user interface design and related timbre space research. Of the three

  16. European Code against Cancer 4th Edition

    DEFF Research Database (Denmark)

    Friis, Søren; Kesminiene, Ausrele; Espina, Carolina

    2015-01-01

    were given for carcinogenic drugs and medical radiation in the 4th edition of European Code against Cancer. It is crucial that the application of these measures relies on medical expertise and thorough benefit-risk evaluation. This also pertains to cancer-preventive drugs, and self-medication...

  17. Efficient Communication Protocols for Deciding Edit Distance

    DEFF Research Database (Denmark)

    Jowhari, Hossein

    2012-01-01

    In this paper we present two communication protocols on computing edit distance. In our first result, we give a one-way protocol for the following Document Exchange problem. Namely given x ∈ Σn to Alice and y ∈ Σn to Bob and integer k to both, Alice sends a message to Bob so that he learns x...... or truthfully reports that the edit distance between x and y is greater than k. For this problem, we give a randomized protocol in which Alice transmits at most O ˜ (klog 2 n) bits and each party’s time complexity is O ˜ (nlogn+k 2 log 2 n) . Our second result is a simultaneous protocol for edit distance over...... permutations. Here Alice and Bob both send a message to a third party (the referee) who does not have access to the input strings. Given the messages, the referee decides if the edit distance between x and y is at most k or not. For this problem we give a protocol in which Alice and Bob run a O...

  18. Ladybugs of South Dakota, 2nd edition

    Science.gov (United States)

    Images of the 80 species of Coccinellidae, commonly known as lady beetles, that occur in South Dakota are presented in taxonomic order. The second edition updates information, including the addition of a species new to South Dakota. Information on each species includes genus-species name, sub-fami...

  19. International guide to the circus. - 2015 edition

    NARCIS (Netherlands)

    Huey, R.; Albrecht, E.; Belbahri, N.; Brunsdale, M.; Christian, J.; Garcia, J.; Giarola, A.; Jando, D.; Lehmann, R.; Marier, F.; Nieminen, K.; Parkinson, G.; Pierce, R.D.; Revolledo Cárdenas, J.; Rodenhuis, W.; Serena, A.; Schlotfeldt, A.; Shaina, C.; Shrake, P.; Simon, M.; St. Leon, M.; Stone, C.; Cooper, J.; Tamaoki, V.; Winkler, G.

    2015-01-01

    An easy-to-read publication defining 100 key circus terms translated in nine languages. The 2015 edition has been re-created in a smaller "pocket" version, 44 pages in length and weighing 63 grams per book. Additional images have been added to illustrate terms and each book is sold complete with a

  20. ETC 408/508: Technical Editing

    Science.gov (United States)

    Charlton, Michael

    2013-01-01

    The course will focus on the role of the editor in organizational settings, including creating successful writer/editor collaboration. Students will gain practice in editing documents for grammar, syntax, organization, style, emphasis, document design, graphics, and user-centered design. The course will provide an introduction to technology for…