Large neutrino mixings in MSSM and SUSY GUTs: Democratic approach

International Nuclear Information System (INIS)

Shafi, Qaisar; Tavartkiladze, Zurab

2003-01-01

We show how, with aid from a U (1) flavor symmetry, the hierarchical structure in the charged fermion sector and a democratic approach for neutrinos that yields large solar and atmospheric neutrino mixings can be simultaneously realized in the MSSM framework. In SU(5), due to the unified multiplets, we encounter difficulties. Namely, democracy for the neutrinos leads to a wrong hierarchical pattern for charged fermion masses and mixings. We discuss how this is overcome in flipped SU(5). We then proceed to an example based on 5D SUSY SU(5) GUT in which the neutrino democracy idea can be realized. A crucial role is played by bulk states, the so-called 'copies', which are split by compactifying the fifth dimension on an S(1)/Z2 x Z'2 orbifold

Unification of SUSY breaking and GUT breaking

Energy Technology Data Exchange (ETDEWEB)

Kobayashi, Tatsuo [Department of Physics, Hokkaido University,Sapporo 060-0810 (Japan); Omura, Yuji [Department of Physics, Nagoya University,Nagoya 464-8602 (Japan)

2015-02-18

We build explicit supersymmetric unification models where grand unified gauge symmetry breaking and supersymmetry (SUSY) breaking are caused by the same sector. Besides, the SM-charged particles are also predicted by the symmetry breaking sector, and they give the soft SUSY breaking terms through the so-called gauge mediation. We investigate the mass spectrums in an explicit model with SU(5) and additional gauge groups, and discuss its phenomenological aspects. Especially, nonzero A-term and B-term are generated at one-loop level according to the mediation via the vector superfields, so that the electro-weak symmetry breaking and 125 GeV Higgs mass may be achieved by the large B-term and A-term even if the stop mass is around 1 TeV.

Hadronic EDMs in SUSY SU(5) GUTs with right-handed neutrinos

International Nuclear Information System (INIS)

Hisano, Junji; Kakizaki, Mitsuru; Nagai, Minoru; Shimizu, Yasuhiro

2004-01-01

We discuss hadronic EDM constraints on the neutrino sector in the SUSY SU(5) GUT with the right-handed neutrinos. The hadronic EDMs are sensitive to the right-handed down-type squark mixings, especially between the second and third generations and between the first and third ones, compared with the other low-energy hadronic observables, and the flavor mixings are induced by the neutrino Yukawa interaction. The current experimental bound of the neutron EDM may imply that the right-handed tau neutrino mass is smaller than about 10 14 GeV in the minimal supergravity scenario, and it may be improved furthermore in future experiments, such as the deuteron EDM measurement

Testing GUTs: where do monopoles fit

International Nuclear Information System (INIS)

Ellis, J.

1982-10-01

The report shows why the inadequacies of the standard model of elementary particles impel some theorists toward embedding the strong, weak and electromagnetic interactions in a simple GUT group, and explains why the grand unification scale and hence the GUM (Grand Unified Monopoles) mass are expected to be so large (greater than or equal to 10 14 GeV). It goes on to describe some model GUTs, notably minimal SU(5) and supersymmetric (susy) GUTs. The grand unified analogues of generalized Cabibbo mixing angles are introduced relevant to the prediction of baryon decay modes in different theories as well as to the Decay modes catalyzed by GUMs. Phenomenologies of conventional and susy GUTs are contrasted including the potential increase in the grand unification scale as well as possible different baryon decay modes in susy GUTs. The phenomenology of GUMs is discussed, principally their ability to catalyze baryon decays. Some of the astrophysical and cosmological constraints on GUMs, GUMs, which make it difficult to imagine ever seeing a GUM and may impose serious restrictions on GUT model-building via their behavior in the very early universe are introduced. Finally, the reasons why GUMs are crucial aspects and tests of GUTs are summarized

Reach of the Fermilab Tevatron and CERN LHC for gaugino mediated SUSY breaking models

International Nuclear Information System (INIS)

Baer, Howard; Belyaev, Alexander; Krupovnickas, Tadas; Tata, Xerxes

2002-01-01

In supersymmetric models with gaugino mediated SUSY breaking (gMSB), it is assumed that SUSY breaking on a hidden brane is communicated to the visible brane via gauge superfields which propagate in the bulk. This leads to GUT models where the common gaugino mass m 1/2 is the only soft SUSY breaking term to receive contributions at the tree level. To obtain a viable phenomenology, it is assumed that the gaugino mass is induced at some scale M c beyond the GUT scale, and that additional renormalization group running takes place between M c and M GUT as in a SUSY GUT. We assume an SU(5) SUSY GUT above the GUT scale, and compute the SUSY particle spectrum expected in models with gMSB. We use the Monte Carlo program ISAJET to simulate signals within the gMSB model, and compute the SUSY reach including cuts and triggers appropriate to Fermilab Tevatron and CERN LHC experiments. We find no reach for SUSY by the Tevatron collider in the trilepton channel. At the CERN LHC, values of m 1/2 =1000 (1160) GeV can be probed with 10 (100) fb -1 of integrated luminosity, corresponding to a reach in terms of m g-tilde of 2150 (2500) GeV. The gMSB model and MSUGRA can likely only be differentiated at a linear e + e - collider with sufficient energy to produce sleptons and charginos

Predictions from a flavour GUT model combined with a SUSY breaking sector

Science.gov (United States)

Antusch, Stefan; Hohl, Christian

2017-10-01

We discuss how flavour GUT models in the context of supergravity can be completed with a simple SUSY breaking sector, such that the flavour-dependent (non-universal) soft breaking terms can be calculated. As an example, we discuss a model based on an SU(5) GUT symmetry and A 4 family symmetry, plus additional discrete "shaping symmetries" and a ℤ 4 R symmetry. We calculate the soft terms and identify the relevant high scale input parameters, and investigate the resulting predictions for the low scale observables, such as flavour violating processes, the sparticle spectrum and the dark matter relic density.

Building GUTs from strings

International Nuclear Information System (INIS)

Aldazabal, G.; Ibanez, L.E.; Uranga, A.M.

1996-01-01

We study in detail the structure of Grand Unified Theories derived as the low-energy limit of orbifold four-dimensional strings. To this aim, new techniques for building level-two symmetric orbifold theories are presented. New classes of GUTs in the context of symmetric orbifolds are then constructed. The method of permutation modding is further explored and SO(10) GUTs with both 45- or 54-plets are obtained. SU(5) models are also found through this method. It is shown that, in the context of symmetric orbifold SO(10) GUTs, only a single GUT Higgs, either a 54 or a 45, can be present and it always resides in an order-two untwisted sector. Very restrictive results also hold in the case of SU(5). General properties and selection rules for string GUTs are described. Some of these selection rules forbid the presence of some particular GUT-Higgs couplings which are sometimes used in SUSY-GUT model building. Some semi-realistic string GUT examples are presented and their properties briefly discussed. (orig.)

Towards a complete Δ(27) × SO(10) GUT of flavour

Science.gov (United States)

Björkeroth, Fredrik

2017-09-01

We propose a renormalisable model based on Δ(27) family symmetry with an SO(10) grand unified theory (GUT) leading to a novel form of spontaneous geometrical CP violation. The symmetries are broken close to the GUT breaking scale to yield the minimal supersymmetric standard model with standard R-parity. Low-scale Yukawa structure is dictated by the coupling of matter to Δ(27) antitriplets \\bar φ whose vacuum expectation values are aligned in the CSD3 directions by the superpotential. Light physical Majorana neutrinos masses emerge from the seesaw mechanism within SO(10). The model predicts a normal neutrino mass hierarchy with the best-fit lightest neutrino mass m 1 ∼ 0.3 meV, CP-violating oscillation phase δl ≈ 280° and the remaining neutrino parameters all within 1σ of their best-fit experimental values.

A realistic extension of gauge-mediated SUSY-breaking model with superconformal hidden sector

International Nuclear Information System (INIS)

Asano, Masaki; Hisano, Junji; Okada, Takashi; Sugiyama, Shohei

2009-01-01

The sequestering of supersymmetry (SUSY) breaking parameters, which is induced by superconformal hidden sector, is one of the solutions for the μ/B μ problem in gauge-mediated SUSY-breaking scenario. However, it is found that the minimal messenger model does not derive the correct electroweak symmetry breaking. In this Letter we present a model which has the coupling of the messengers with the SO(10) GUT-symmetry breaking Higgs fields. The model is one of the realistic extensions of the gauge mediation model with superconformal hidden sector. It is shown that the extension is applicable for a broad range of conformality breaking scale

D-term contributions and CEDM constraints in E6 × SU(2)F × U(1)A SUSY GUT model

Science.gov (United States)

Shigekami, Yoshihiro

2017-11-01

We focus on E6 × SU(2)F × U(1)A supersymmetric (SUSY) grand unified theory (GUT) model. In this model, realistic Yukawa hierarchies and mixings are realized by introducing all allowed interactions with 𝓞(1) coefficients. Moreover, we can take stop mass is smaller than the other sfermion masses. This type of spectrum called by natural SUSY type sfermion mass spectrum can suppress the SUSY contributions to flavor changing neutral current (FCNC) and stabilize weak scale at the same time. However, light stop predicts large up quark CEDM and stop contributions are not decoupled. Since there is Kobayashi-Maskawa phase, stop contributions to the up quark CEDM is severely constrained even if all SUSY breaking parameters and Higgsino mass parameter μ are real. In this model, real up Yukawa couplings are realized at the GUT scale because of spontaneous CP violation. Therefore CEDM bounds are satisfied, although up Yukawa couplings are complex at the SUSY scale through the renormalization equation group effects. We calculated the CEDMs and found that EDM constraints can be satisfied even if stop mass is 𝓞(1) TeV. In addition, we investigate the size of D-terms in this model. Since these D-term contributions is flavor dependent, the degeneracy of sfermion mass spectrum is destroyed and the size of D-term is strongly constrained by FCNCs when SUSY breaking scale is the weak scale. However, SUSY breaking scale is larger than 1 TeV in order to obtain 125 GeV Higgs mass, and therefore sizable D-term contribution is allowed. Furthermore, we obtained the non-trivial prediction for the difference of squared sfermion mass.

Primordial cosmological inflation versus local supersymmetry breaking in SUSY GUTs coupled to N = 1 supergravity

International Nuclear Information System (INIS)

Gato, B.; Leon, J.; Ramon-Medrano, M.

1984-01-01

We present a model for a SUSY GUT coupled to N=1 supergravity in which local supersymmetry breaks down in the gauge singlet sector. The constraints for the model to be physically acceptable are incompatible with inflation. The simultaneous breaking of local supersymmetry and gauge symmetry is proposed as a good prospect for inflation. (orig.)

Flipped SO(10) model

Energy Technology Data Exchange (ETDEWEB)

Maekawa, Nobuhiro; Yamashita, Toshifumi

2003-08-14

This Letter demonstrates that, as in flipped SU(5) models, doublet-triplet splitting is accomplished by a missing partner mechanism in flipped SO(10) models. The gauge group SO(10){sub F}xU(1){sub V'{sub F}} includes SU(2){sub E} gauge symmetry, which plays an important role in solving the supersymmetric (SUSY) flavor problem by introducing non-abelian horizontal gauge symmetry and anomalous U(1){sub A} gauge symmetry. The gauge group can be broken into the standard model gauge group by VEVs of only spinor fields; such models may be easier to derive than E{sub 6} models from superstring theory.

Viable and testable SUSY GUTs with Yukawa unification the case of split trilinears

CERN Document Server

Guadagnoli, Diego; Straub, David M

2009-01-01

We explore general SUSY GUT models with exact third-generation Yukawa unification, but where the requirement of universal soft terms at the GUT scale is relaxed. We consider the scenario in which the breaking of universality inherits from the Yukawa couplings, i.e. is of minimal flavor violating (MFV) type. In particular, the MFV principle allows for a splitting between the up-type and the down-type soft trilinear couplings. We explore the viability of this trilinear splitting scenario by means of a fitting procedure to electroweak observables, quark masses as well as flavor-changing neutral current processes. Phenomenological viability singles out one main scenario. This scenario is characterized by a sizable splitting between the trilinear soft terms and a large mu term. Remarkably, this scenario does not invoke a partial decoupling of the sparticle spectrum, as in the case of universal soft terms, but instead it requires part of the spectrum, notably the lightest stop, the gluino and the lightest charginos...

Ten dimensional SO(10) G.U.T. models with dynamical symmetry breaking

International Nuclear Information System (INIS)

Hanlon, B.E.; Joshi, G.C.

1993-01-01

To date, considerations on SO (10) models within Coset Space Dimensional Reduction (CSDR) have been diagonalized to the standard model or rely upon imaginative applications of Wilson lines so as to avoid the problem of the nonexistence of an intermediate Higgs mechanism. However, there is an alternative approach involving four fermion condensates, breaking symmetries by a dynamical mechanism. Indeed, dynamical symmetry breaking has been the direction taken in some SU(5) models within this framework in order to avoid the problems of electroweak symmetry breaking at the compactification scale. This paper presents realistic models which utilize this mechanism. It is shown that the appropriate fermionic representations can emerge from CSDR and the construction of such condensates within the constraints of this scheme is presented. By introducing discrete symmetries onto the internal manifold a strong breaking of the SO(10) G.U.T. is produced and, more importantly, eliminate Higgs fields of geometrical origin. 31 refs

Where is SUSY?

CERN Multimedia

Antonella Del Rosso

2012-01-01

Recent information from the LHC experiments, the relatively low mass of the new boson and other data coming from experiments looking for dark matter worldwide are placing new constraints on the existence of supersymmetry (SUSY). However, there is a large community of scientists that still believes that SUSY particles are out there. Like lost keys at night, perhaps we have been looking for SUSY under the wrong lamp-posts…   Can you work out this rebus? Source: Caroline Duc. So far, SUSY is “just” a theoretical physics model, which could solve problems beyond the Standard Model by accounting for dark matter and other phenomena in the Universe. However, SUSY has not been spotted so far, and might be hiding because of features different from what physicists previously expected. “Currently, there is no evidence for SUSY, but neither has any experimental data ruled it out. Many searches have focused on simplified versions of the theory but, given the recen...

Hilltop supernatural inflation and SUSY unified models

International Nuclear Information System (INIS)

Kohri, Kazunori; Lim, C.S.; Lin, Chia-Min; Mimura, Yukihiro

2014-01-01

In this paper, we consider high scale (100TeV) supersymmetry (SUSY) breaking and realize the idea of hilltop supernatural inflation in concrete particle physics models based on flipped-SU(5)and Pati-Salam models in the framework of supersymmetric grand unified theories (SUSY GUTs). The inflaton can be a flat direction including right-handed sneutrino and the waterfall field is a GUT Higgs. The spectral index is n s = 0.96 which fits very well with recent data by PLANCK satellite. There is no both thermal and non-thermal gravitino problems. Non-thermal leptogenesis can be resulted from the decay of right-handed sneutrino which plays (part of) the role of inflaton

Hilltop supernatural inflation and SUSY unified models

Science.gov (United States)

Kohri, Kazunori; Lim, C. S.; Lin, Chia-Min; Mimura, Yukihiro

2014-01-01

In this paper, we consider high scale (100TeV) supersymmetry (SUSY) breaking and realize the idea of hilltop supernatural inflation in concrete particle physics models based on flipped-SU(5)and Pati-Salam models in the framework of supersymmetric grand unified theories (SUSY GUTs). The inflaton can be a flat direction including right-handed sneutrino and the waterfall field is a GUT Higgs. The spectral index is ns = 0.96 which fits very well with recent data by PLANCK satellite. There is no both thermal and non-thermal gravitino problems. Non-thermal leptogenesis can be resulted from the decay of right-handed sneutrino which plays (part of) the role of inflaton.

Hilltop supernatural inflation and SUSY unified models

Energy Technology Data Exchange (ETDEWEB)

Kohri, Kazunori [Cosmophysics Group, Theory Center, IPNS KEK, and The Graduate University for Advanced Studies (Sokendai), 1-1 Oho, Tsukuba, 305-0801 (Japan); Lim, C.S. [Department of Mathematics, Tokyo Woman' s Christian University, Tokyo, 167-8585 (Japan); Lin, Chia-Min [Department of Physics, Chuo University, Bunkyo-ku, Tokyo, 112 (Japan); Mimura, Yukihiro, E-mail: kohri@post.kek.jp, E-mail: lim@lab.twcu.ac.jp, E-mail: lin@chuo-u.ac.jp, E-mail: mimura@hep1.phys.ntu.edu.tw [Department of Physics, National Taiwan University, Taipei, 10617 Taiwan (China)

2014-01-01

In this paper, we consider high scale (100TeV) supersymmetry (SUSY) breaking and realize the idea of hilltop supernatural inflation in concrete particle physics models based on flipped-SU(5)and Pati-Salam models in the framework of supersymmetric grand unified theories (SUSY GUTs). The inflaton can be a flat direction including right-handed sneutrino and the waterfall field is a GUT Higgs. The spectral index is n{sub s} = 0.96 which fits very well with recent data by PLANCK satellite. There is no both thermal and non-thermal gravitino problems. Non-thermal leptogenesis can be resulted from the decay of right-handed sneutrino which plays (part of) the role of inflaton.

Examining a renormalizable supersymmetric SO(10) model

Energy Technology Data Exchange (ETDEWEB)

Chen, Zhi-Yong; Zhang, Da-Xin [Peking University, School of Physics and State Key Laboratory of Nuclear Physics and Technology, Beijing (China)

2017-10-15

We examine a renormalizable SUSY SO(10) model without fine-tuning. We show how to construct MSSM doublets and to predict proton decay. We find that in the minimal set of Yukawa couplings the model is consistent with the experiments, while including 120{sub H} to fit the data there are inconsistencies. (orig.)

Hadronic EDM constraints on orbifold GUTs

International Nuclear Information System (INIS)

Hisano, Junji; Kakizaki, Mitsuru; Nagai, Minoru

2005-01-01

We point out that the null results of the hadronic electric dipole moment (EDM) searches constrain orbifold grand unified theories (GUTs), where the GUT symmetry and supersymmetry (SUSY) are both broken by boundary conditions in extra dimensions and it leads to rich fermion and sfermion flavor structures. A marginal chromoelectric dipole moment (CEDM) of the up quark is induced by the misalignment between the CP violating left- and right-handed up-type squark mixings, in contrast to the conventional four-dimensional SUSY GUTs. The up quark CEDM constraint is found to be as strong as those from charged lepton flavor violation (LFV) searches. The interplay between future EDM and LFV experiments will probe the structures of the GUTs and the SUSY breaking mediation mechanism

F-theory, GUTs, and the weak scale

International Nuclear Information System (INIS)

Heckman, Jonathan J.; Vafa, Cumrun

2009-01-01

In this paper we study a deformation of gauge mediated supersymmetry breaking in a class of local F-theory GUT models where the scale of supersymmetry breaking determines the value of the μ term. Geometrically correlating these two scales constrains the soft SUSY breaking parameters of the MSSM. In this scenario, the hidden SUSY breaking sector involves an anomalous U(1) Peccei-Quinn symmetry which forbids bare μ and Bμ terms. This sector typically breaks supersymmetry at the desired range of energy scales through a simple stringy hybrid of a Fayet and Polonyi model. A variant of the Giudice-Masiero mechanism generates the value μ ∼ 10 2 -10 3 GeV when the hidden sector scale of supersymmetry breaking is F 1/2 ∼ 10 8.5 GeV. Further, the Bμ problem is solved due to the mild hierarchy between the GUT scale and Planck scale. These models relate SUSY breaking with the QCD axion, and solve the strong CP problem through an axion with decay constant f a ∼ M GUT cμ/Λ, where Λ ∼ 10 5 GeV is the characteristic scale of gaugino mass unification in gauge mediated models, and the ratio μ/Λ ∼ M GUT /M pl ∼ 10 -3 . We find f a ∼ 10 12 GeV, which is near the high end of the phenomenologically viable window. Here, the axino is the goldstino mode which is eaten by the gravitino. The gravitino is the LSP with a mass of about 10 1 -10 2 MeV, and a bino-like neutralino is (typically) the NLSP with mass of about 10 2 -10 3 GeV. Compatibility with electroweak symmetry breaking also determines the value of tanβ ∼ 30±7.

Threshold corrections to dimension-six proton decay operators in non-minimal SUSY SU(5 GUTs

Directory of Open Access Journals (Sweden)

Borut Bajc

2016-09-01

Full Text Available We calculate the high and low scale threshold corrections to the D=6 proton decay mode in supersymmetric SU(5 grand unified theories with higher-dimensional representation Higgs multiplets. In particular, we focus on a missing-partner model in which the grand unified group is spontaneously broken by the 75-dimensional Higgs multiplet and the doublet–triplet splitting problem is solved. We find that in the missing-partner model the D=6 proton decay rate gets suppressed by about 60%, mainly due to the threshold effect at the GUT scale, while the SUSY-scale threshold corrections are found to be less prominent when sfermions are heavy.

GUTs and supersymmetric GUTs in the very early universe

International Nuclear Information System (INIS)

Ellis, J.

1983-01-01

This talk is intended as background material for many of the other talks treating the possible applications of GUTs to the very early universe. It starts with a review of the present theoretical and phenomenological status of GUTs and then goes on to raise some new issues for their prospective cosmological applications which arise in supersymmetric (susy) GUTs. (author)

Non-universal gaugino mass GUT models in the light of dark matter and LHC constraints

International Nuclear Information System (INIS)

Chakrabortty, Joydeep; Mohanty, Subhendra; Rao, Soumya

2014-01-01

We perform a comprehensive study of SU(5), SO(10) and E(6) supersymmetric GUT models where the gaugino masses are generated through the F-term breaking vacuum expectation values of the non-singlet scalar fields. In these models the gauginos are non-universal at the GUT scale unlike in the mSUGRA scenario. We discuss the properties of the LSP which is stable and a viable candidate for cold dark matter. We look for the GUT scale parameter space that leads to the the lightest SM like Higgs mass in the range of 122–127 GeV compatible with the observations at ATLAS and CMS, the relic density in the allowed range of WMAP-PLANCK and compatible with other constraints from colliders and direct detection experiments. We scan universal scalar (m 0 G ), trilinear coupling A 0 and SU(3) C gaugino mass (M 3 G ) as the independent free parameters for these models. Based on the gaugino mass ratios at the GUT scale, we classify 25 SUSY GUT models and find that of these only 13 models satisfy the dark matter and collider constraints. Out of these 13 models there is only one model where there is a sizeable SUSY contribution to muon (g−2)

Flipped SO(10)

Energy Technology Data Exchange (ETDEWEB)

Tamvakis, K.

1988-01-28

We construct an N=1 supersymmetric SO(10) GUT broken down to SU(3)c x SU(2)/sub L/ x U(1)/sub ..gamma../ with an intermediate flipped SU(5) x U(1)/sub chi/ gauge symmetry. A solution to the triplet-doublet mass-splitting problem is proposed in terms of a non-minimal missing-partner mechanism.

Natural SUSY dark matter model

International Nuclear Information System (INIS)

Mohanty, Subhendra; Rao, Soumya; Roy, D.P.

2013-01-01

The most natural region of cosmologically compatible dark matter relic density in terms of low fine-tuning in a minimal supersymmetric standard model with nonuniversal gaugino masses is the so called bulk annihilation region. We study this region in a simple and predictive SUSY- GUT model of nonuniversal gaugino masses, where the latter transform as a combination of singlet plus a nonsinglet representation of the GUTgroup SU(5). The model prediction for the direct dark matter detection rates is well below the present CDMS and XENON100 limits, but within the reach of a future 1Ton XENON experiment. The most interesting and robust model prediction is an indirect detection signal of hard positron events, which resembles closely the shape of the observed positron spectrum from the PAMELA experiment. (author)

SUSY Without Prejudice

International Nuclear Information System (INIS)

Berger, C.

2008-01-01

We begin an exploration of the physics associated with the general CP-conserving MSSM with Minimal Flavor Violation, the pMSSM. The 19 soft SUSY breaking parameters in this scenario are chosen so as to satisfy all existing experimental and theoretical constraints assuming that the WIMP is a thermal relic, i.e., the lightest neutralino. We scan this parameter space twice using both flat and log priors for the soft SUSY breaking mass parameters and compare the results which yield similar conclusions. Detailed constraints from both LEP and the Tevatron searches play a particularly important role in obtaining our final model samples. We find that the pMSSM leads to a much broader set of predictions for the properties of the SUSY partners as well as for a number of experimental observables than those found in any of the conventional SUSY breaking scenarios such as mSUGRA. This set of models can easily lead to atypical expectations for SUSY signals at the LHC

A non Supersymmetric SO(10) Grand Unified Model for All the Physics below $M_{GUT}$

CERN Document Server

Altarelli, Guido

2013-01-01

We present a renormalizable non supersymmetric Grand Unified SO(10) model which, at the price of a large fine tuning, is compatible with all compelling phenomenological requirements below the unification scale and thus realizes a minimal extension of the SM, unified in SO(10) and describing all known physics below $M_{GUT}$. These requirements include coupling unification at a large enough scale to be compatible with the bounds on proton decay; a Yukawa sector in agreement with all the data on quark and lepton masses and mixings and with leptogenesis as the origin of the baryon asymmetry of the Universe; an axion arising from the Higgs sector of the model, suitable to solve the strong CP problem and to account for the observed amount of Dark Matter. The above constraints imposed by the data are very stringent and single out a particular breaking chain with the Pati-Salam group at an intermediate scale $M_I\\sim10^{11}$ GeV.

Toward the realistic three-generation model in the (2,0) heterotic string compactification

International Nuclear Information System (INIS)

Asatryan, H.M.; Murayama, A.

1992-01-01

In this paper, the three generation models with SUSY SO(10) or SU(5) GUTs derived from the (2,0) compactification of E 8 x E' 8 heterotic string, the massless matter field spectra at the GUT scale M X and the breaking directions of GUT symmetries are discussed. A pseudo-left-right symmetric Pati-Salam model is naturally deduced in the SUSY SO(10) GUT and shown to have an interesting property, M x ≅ M P1 , M R ≅ 10 10 GeV and M S ( the scale of superpartner masses) ≅ 10 4 GeV, as a result of the renormalization group equation analysis using the new precise LEP data

Antisymmetric Higgs representation in SO(10) for neutrinos

International Nuclear Information System (INIS)

Oshimo, Noriyuki

2002-01-01

A model based on SO(10) grand unified theory (GUT) and supersymmetry is presented to describe phenomena observed for neutrinos. The large mixing angles among different generations, together with the small masses, are attributed to the Higgs boson structure at the GUT energy scale. Quantitative discussions of these observables are given, taking into account their energy evolution

Likelihood analysis of supersymmetric SU(5) GUTs

Energy Technology Data Exchange (ETDEWEB)

Bagnaschi, E.; Weiglein, G. [DESY, Hamburg (Germany); Costa, J.C.; Buchmueller, O.; Citron, M.; Richards, A.; De Vries, K.J. [Imperial College, High Energy Physics Group, Blackett Laboratory, London (United Kingdom); Sakurai, K. [University of Durham, Science Laboratories, Department of Physics, Institute for Particle Physics Phenomenology, Durham (United Kingdom); University of Warsaw, Faculty of Physics, Institute of Theoretical Physics, Warsaw (Poland); Borsato, M.; Chobanova, V.; Lucio, M.; Martinez Santos, D. [Universidade de Santiago de Compostela, Santiago de Compostela (Spain); Cavanaugh, R. [Fermi National Accelerator Laboratory, Batavia, IL (United States); University of Illinois at Chicago, Physics Department, Chicago, IL (United States); Roeck, A. de [CERN, Experimental Physics Department, Geneva (Switzerland); Antwerp University, Wilrijk (Belgium); Dolan, M.J. [University of Melbourne, ARC Centre of Excellence for Particle Physics at the Terascale, School of Physics, Parkville (Australia); Ellis, J.R. [King' s College London, Theoretical Particle Physics and Cosmology Group, Department of Physics, London (United Kingdom); Theoretical Physics Department, CERN, Geneva 23 (Switzerland); Flaecher, H. [University of Bristol, H.H. Wills Physics Laboratory, Bristol (United Kingdom); Heinemeyer, S. [Campus of International Excellence UAM+CSIC, Cantoblanco, Madrid (Spain); Instituto de Fisica Teorica UAM-CSIC, Madrid (Spain); Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain); Isidori, G. [Universitaet Zuerich, Physik-Institut, Zurich (Switzerland); Olive, K.A. [University of Minnesota, William I. Fine Theoretical Physics Institute, School of Physics and Astronomy, Minneapolis, MN (United States)

2017-02-15

We perform a likelihood analysis of the constraints from accelerator experiments and astrophysical observations on supersymmetric (SUSY) models with SU(5) boundary conditions on soft SUSY-breaking parameters at the GUT scale. The parameter space of the models studied has seven parameters: a universal gaugino mass m{sub 1/2}, distinct masses for the scalar partners of matter fermions in five- and ten-dimensional representations of SU(5), m{sub 5} and m{sub 10}, and for the 5 and anti 5 Higgs representations m{sub H{sub u}} and m{sub H{sub d}}, a universal trilinear soft SUSY-breaking parameter A{sub 0}, and the ratio of Higgs vevs tan β. In addition to previous constraints from direct sparticle searches, low-energy and flavour observables, we incorporate constraints based on preliminary results from 13 TeV LHC searches for jets + E{sub T} events and long-lived particles, as well as the latest PandaX-II and LUX searches for direct Dark Matter detection. In addition to previously identified mechanisms for bringing the supersymmetric relic density into the range allowed by cosmology, we identify a novel u{sub R}/c{sub R} - χ{sup 0}{sub 1} coannihilation mechanism that appears in the supersymmetric SU(5) GUT model and discuss the role of ν{sub τ} coannihilation. We find complementarity between the prospects for direct Dark Matter detection and SUSY searches at the LHC. (orig.)

Likelihood analysis of supersymmetric SU(5) GUTs

Energy Technology Data Exchange (ETDEWEB)

Bagnaschi, E. [DESY, Hamburg (Germany); Costa, J.C. [Imperial College, London (United Kingdom). Blackett Lab.; Sakurai, K. [Durham Univ. (United Kingdom). Inst. for Particle Physics Phenomonology; Warsaw Univ. (Poland). Inst. of Theoretical Physics; Collaboration: MasterCode Collaboration; and others

2016-10-15

We perform a likelihood analysis of the constraints from accelerator experiments and astrophysical observations on supersymmetric (SUSY) models with SU(5) boundary conditions on soft SUSY-breaking parameters at the GUT scale. The parameter space of the models studied has 7 parameters: a universal gaugino mass m{sub 1/2}, distinct masses for the scalar partners of matter fermions in five- and ten-dimensional representations of SU(5), m{sub 5} and m{sub 10}, and for the 5 and anti 5 Higgs representations m{sub H{sub u}} and m{sub H{sub d}}, a universal trilinear soft SUSY-breaking parameter A{sub 0}, and the ratio of Higgs vevs tan β. In addition to previous constraints from direct sparticle searches, low-energy and avour observables, we incorporate constraints based on preliminary results from 13 TeV LHC searches for jets+E{sub T} events and long-lived particles, as well as the latest PandaX-II and LUX searches for direct Dark Matter detection. In addition to previously-identified mechanisms for bringing the supersymmetric relic density into the range allowed by cosmology, we identify a novel u{sub R}/c{sub R}-χ{sup 0}{sub 1} coannihilation mechanism that appears in the supersymmetric SU(5) GUT model and discuss the role of ν{sub T} coannihilation. We find complementarity between the prospects for direct Dark Matter detection and SUSY searches at the LHC.

FlexibleSUSY-A spectrum generator generator for supersymmetric models

Science.gov (United States)

Athron, Peter; Park, Jae-hyeon; Stöckinger, Dominik; Voigt, Alexander

2015-05-01

We introduce FlexibleSUSY, a Mathematica and C++ package, which generates a fast, precise C++ spectrum generator for any SUSY model specified by the user. The generated code is designed with both speed and modularity in mind, making it easy to adapt and extend with new features. The model is specified by supplying the superpotential, gauge structure and particle content in a SARAH model file; specific boundary conditions e.g. at the GUT, weak or intermediate scales are defined in a separate FlexibleSUSY model file. From these model files, FlexibleSUSY generates C++ code for self-energies, tadpole corrections, renormalization group equations (RGEs) and electroweak symmetry breaking (EWSB) conditions and combines them with numerical routines for solving the RGEs and EWSB conditions simultaneously. The resulting spectrum generator is then able to solve for the spectrum of the model, including loop-corrected pole masses, consistent with user specified boundary conditions. The modular structure of the generated code allows for individual components to be replaced with an alternative if available. FlexibleSUSY has been carefully designed to grow as alternative solvers and calculators are added. Predefined models include the MSSM, NMSSM, E6SSM, USSM, R-symmetric models and models with right-handed neutrinos.

Quark and lepton masses at the GUT scale including supersymmetric threshold corrections

International Nuclear Information System (INIS)

Antusch, S.; Spinrath, M.

2008-01-01

We investigate the effect of supersymmetric (SUSY) threshold corrections on the values of the running quark and charged lepton masses at the grand unified theory (GUT) scale within the large tanβ regime of the minimal supersymmetric standard model. In addition to the typically dominant SUSY QCD contributions for the quarks, we also include the electroweak contributions for quarks and leptons and show that they can have significant effects. We provide the GUT scale ranges of quark and charged lepton Yukawa couplings as well as of the ratios m μ /m s , m e /m d , y τ /y b and y t /y b for three example ranges of SUSY parameters. We discuss how the enlarged ranges due to threshold effects might open up new possibilities for constructing GUT models of fermion masses and mixings.

SUSY meets her twin

Energy Technology Data Exchange (ETDEWEB)

Katz, Andrey [Theory Division, CERN,CH-1211 Geneva 23 (Switzerland); Département de Physique Théorique and Center for Astroparticle Physics (CAP),Université de Genève,24 quai Ansermet, CH-1211 Genève 4 (Switzerland); Mariotti, Alberto [Theoretische Natuurkunde and IIHE/ELEM, Vrije Universiteit Brussel,and International Solvay Institutes,Pleinlaan 2, B-1050 Brussels (Belgium); Pokorski, Stefan [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,ul. Pasteura 5, PL-02-093 Warsaw (Poland); Redigolo, Diego [Raymond and Beverly Sackler School of Physics and Astronomy, Tel-Aviv University,Tel-Aviv 69978 (Israel); Department of Particle Physics and Astrophysics, Weizmann Institute of Science,Rehovot 7610001 (Israel); Ziegler, Robert [Institute for Theoretical Particle Physics (TTP), Karlsruhe Institute of Technology,Engesserstraße 7, D-76128 Karlsruhe (Germany)

2017-01-31

We investigate the general structure of mirror symmetry breaking in the Twin Higgs scenario. We show, using the IR effective theory, that a significant gain in fine tuning can be achieved if the symmetry is broken hardly. We emphasize that weakly coupled UV completions can naturally accommodate this scenario. We analyze SUSY UV completions and present a simple Twin SUSY model with a tuning of around 10% and colored superpartners as heavy as 2 TeV. The collider signatures of general Twin SUSY models are discussed with a focus on the extended Higgs sectors.

Likelihood Analysis of Supersymmetric SU(5) GUTs

CERN Document Server

Bagnaschi, E.

2017-01-01

We perform a likelihood analysis of the constraints from accelerator experiments and astrophysical observations on supersymmetric (SUSY) models with SU(5) boundary conditions on soft SUSY-breaking parameters at the GUT scale. The parameter space of the models studied has 7 parameters: a universal gaugino mass $m_{1/2}$, distinct masses for the scalar partners of matter fermions in five- and ten-dimensional representations of SU(5), $m_5$ and $m_{10}$, and for the $\\mathbf{5}$ and $\\mathbf{\\bar 5}$ Higgs representations $m_{H_u}$ and $m_{H_d}$, a universal trilinear soft SUSY-breaking parameter $A_0$, and the ratio of Higgs vevs $\\tan \\beta$. In addition to previous constraints from direct sparticle searches, low-energy and flavour observables, we incorporate constraints based on preliminary results from 13 TeV LHC searches for jets + MET events and long-lived particles, as well as the latest PandaX-II and LUX searches for direct Dark Matter detection. In addition to previously-identified mechanisms for bringi...

Superstring-inspired SO(10) GUT model with intermediate scale

Science.gov (United States)

Sasaki, Ken

1987-12-01

A new mechanism is proposed for the mixing of Weinberg-Salam Higgs fields in superstring-inspired SO(10) models with no SO(10) singlet fields. The higher-dimensional terms in the superpotential can generate both Higgs field mixing and a small mass for the physical neutrino. I would like to thank Professor C. Iso for hospitality extended to me at the Tokyo Institute of Technology.

Spontaneous SUSY breaking without R symmetry in supergravity

Science.gov (United States)

Maekawa, Nobuhiro; Omura, Yuji; Shigekami, Yoshihiro; Yoshida, Manabu

2018-03-01

We discuss spontaneous supersymmetry (SUSY) breaking in a model with an anomalous U (1 )A symmetry. In this model, the size of the each term in the superpotential is controlled by the U (1 )A charge assignment and SUSY is spontaneously broken via the Fayet-Iliopoulos of U (1 )A at the metastable vacuum. In the global SUSY analysis, the gaugino masses become much smaller than the sfermion masses, because an approximate R symmetry appears at the SUSY breaking vacuum. In this paper, we show that gaugino masses can be as large as gravitino mass, taking the supergravity effect into consideration. This is because the R symmetry is not imposed so that the constant term in the superpotential, which is irrelevant to the global SUSY analysis, largely contributes to the soft SUSY breaking terms in the supergravity. As the mediation mechanism, we introduce the contributions of the field not charged under U (1 )A and the moduli field to cancel the anomaly of U (1 )A. We comment on the application of our SUSY breaking scenario to the grand unified theory.

Signatures of non-universal soft breaking sfermion masses at Hadron colliders

International Nuclear Information System (INIS)

Datta, Amitava; Datta, Aseshkrishna; Parida, M.K.

1997-12-01

We identify several mass patterns, within the framework of N = 1 SUGRA with nonuniversal soft breaking masses for the sfermions, which may significantly alter SUSY signals and the current squark-gluino mass limits from the Tevatron. These effects are illustrated in a SO(10) SUSY GUT with an intermediate mass scale, but the conclusions are also valid in SUSU SO(10) models with grand deserts. (author)

New GUT predictions for mτ/mb and mμ/ms

International Nuclear Information System (INIS)

Antusch, Stefan

2010-01-01

Group theoretical factors from GUT symmetry breaking can lead to predictions for the ratios of quark and lepton masses (or Yukawa couplings) at the unification scale. Due to supersymmetric (SUSY) threshold corrections the viability of such predictions can depend strongly on the SUSY parameters. For three common minimal SUSY breaking scenarios with anomaly, gauge and gravity mediation we discuss which GUT scale ratios m e /m d m μ /m s , y τ /y b and y t /y b are allowed when phenomenological constraints from electroweak precision observables, B physics, (g - 2) μ , mass-limits on sparticles from direct searches as well as, optionally, constraints from the observed dark matter density are taken into account. We derive possible new predictions for the GUT scale mass ratios and compare them with the phenomenologically allowed ranges. We find that new GUT scale predictions such as m μ /m s = 9/2 or 6 and y τ /y b = 3/2 or 2 are often favoured compared to the ubiquitous relations m μ /m s = 3 or y τ /y b = 1. The talk is based on the results obtained in Refs. [1, 2].

Neutrino mixing and masses in SO(10) GUTs with hidden sector and flavor symmetries

Energy Technology Data Exchange (ETDEWEB)

Chu, Xiaoyong [International Centre for Theoretical Physics,Strada Costiera 11, I-34100 Trieste (Italy); Smirnov, Alexei Yu. [Max-Planck-Institute for Nuclear Physics,Saupfercheckweg 1, D-69117 Heidelberg (Germany); International Centre for Theoretical Physics,Strada Costiera 11, I-34100 Trieste (Italy)

2016-05-23

We consider the neutrino masses and mixing in the framework of SO(10) GUTs with hidden sector consisting of fermionic and bosonic SO(10) singlets and flavor symmetries. The framework allows to disentangle the CKM physics responsible for the CKM mixing and different mass hierarchies of quarks and leptons and the neutrino new physics which produces smallness of neutrino masses and large lepton mixing. The framework leads naturally to the relation U{sub PMNS}∼V{sub CKM}{sup †}U{sub 0}, where structure of U{sub 0} is determined by the flavor symmetry. The key feature of the framework is that apart from the Dirac mass matrices m{sub D}, the portal mass matrix M{sub D} and the mass matrix of singlets M{sub S} are also involved in generation of the lepton mixing. This opens up new possibilities to realize the flavor symmetries and explain the data. Using A{sub 4}×Z{sub 4} as the flavor group, we systematically explore the flavor structures which can be obtained in this framework depending on field content and symmetry assignments. We formulate additional conditions which lead to U{sub 0}∼U{sub TBM} or U{sub BM}. They include (i) equality (in general, proportionality) of the singlet flavons couplings, (ii) equality of their VEVs; (iii) correlation between VEVs of singlets and triplet, (iv) certain VEV alignment of flavon triplet(s). These features can follow from additional symmetries or be remnants of further unification. Phenomenologically viable schemes with minimal flavon content and minimal number of couplings are constructed.

Kepribadian Dan Komunikasi Susi Pudjiastuti Dalam Membentuk Personal Branding

Directory of Open Access Journals (Sweden)

Stevani

2017-07-01

Full Text Available The life story of Susi Pudjiastuti is admired by many people for her hard work, until becoming successful by having so much company in the field of aviation and fisheries. Susi Pudjiastuti is also well known to the public for his work in the ministry. Good performance makes Susi Pudjiastuti popular among Jokowi's working cabinet. Currently, the Brand Name in humans is personal branding which is the trend of the formation of self-image and the creation of good perception from others to us. This research will discuss about personality, communication and personal branding Susi Pudjiastuti with qualitative research method. Good personality makes Susi Pudjiastuti has the ability to communicate well and liked by the community. Personality and communication can form a personal branding Susi Pudjiastuti a natural. By exposing the personality and communication of Susi Pudjiastuti in forming personal branding, then people will realize the importance of personality and Communication in forming a natural personal branding. Kisah hidup Susi Pudjiastuti banyak dikagumi oleh banyak orang atas kerja kerasnya hingga menjadi sukses dengan memiliki banyak perusahaan di bidang penerbangan dan perikanan. Susi Pudjiastuti juga dikenal baik oleh masyarakat akan kinerjanya dalam bekerja di kementerian. Kinerja yang baik menjadikan Susi Pudjiastuti popular diantara kabinet kerja Jokowi. Saat ini, Sebutan merek pada manusia adalah personal branding yang merupakan trend dari pembentukan pencitraan diri dan penciptaan persepsi yang baik dari orang lain kepada kita. Penelitian ini akan membahas mengenai kepribadian, komunikasi serta personal branding Susi Pudjiastuti dengan metode penelitian kualitatif. Kepribadian yang baik menjadikan Susi Pudjiastuti memiliki kemampuan berkomunikasi dengan baik dan disenangi oleh masyarakat. Kepribadian dan komunikasi tersebut dapat membentuk personal branding Susi Pudjiastuti yang alami. Dengan memaparkan kepribadian dan komunikasi Susi

New hierarchy in GUTs based on SU(n,1)/SU(n)U(1) SUGRA

International Nuclear Information System (INIS)

Hayashi, M.J.; Murayama, Akihiro

1985-01-01

Grand unified theories (GUTs) in the framework of SU(n, 1)/SU(n) x U(1) supergravity are discussed which naturally generate a new hierarchy, Msub(P) (Planck mass): Msub(X) (GUT scale):msub(3/2) (gravitino mass):m (explicit supersymmetry breaking scale)=1:epsilon:epsilon 3 :epsilon 5 α(Msub(X)) with Msub(P) as the only input mass scale. The SUSY breaking scale m is expected to be fixed radiatively as mproportionalMsub(W), i.e., epsilonproportional10 -3 . Our method would be applicable to any GUT based on SU(n, 1)/SU(n) x U(1) supergravity. (orig.)

Squarks and sleptons between branes and bulk. Gaugino meditation and gravitino dark matter in an SO(10) orbifold GUT

Energy Technology Data Exchange (ETDEWEB)

Kersten, J.

2006-05-15

We study gaugino-mediated supersymmetry breaking in a six-dimensional SO(10) orbifold GUT model where quarks and leptons are mixtures of brane and bulk fields. The couplings of bulk matter fields to the supersymmetry breaking brane field have to be suppressed in order to avoid large FCNCs. We derive bounds on the soft supersymmetry breaking parameters and calculate the superparticle mass spectrum. If the gravitino is the LSP, the {tau}{sub 1} or the {nu}{sub {tau}}{sub L} turns out to be the NLSP, with characteristic signatures at future colliders and in cosmology. (Orig.)

New minimal SO(10) GUT: A theory for all epochs

Indian Academy of Sciences (India)

[16,17] and are also reported in these proceedings in the contributions of Ila Garg and ..... maintaining realism in the fermion and GUT SSB sector and accounting for low- and .... a lily already well enamelled: as maintained by these authors.

Status of SUSY searches at the LHC (including SUSY Higgs bosons)

CERN Document Server

Marshall, Zach; The ATLAS collaboration

2017-01-01

We review the status of SUSY searches at the LHC, including searches for SUSY Higgs Bosons. ATLAS and CMS have both prepared a large number of search results on the full 2015+2016 dataset, pushing the bounds on SUSY further than ever before.

A continuous family of realistic SUSY SU(5) GUTs

Energy Technology Data Exchange (ETDEWEB)

Bajc, Borut, E-mail: borut.bajc@ijs.si [J. Stefan Institute, Jamova cesta 39, 1000, Ljubljana (Slovenia)

2016-06-21

It is shown that the minimal renormalizable supersymmetric SU(5) is still realistic providing the supersymmetric scale is at least few tens of TeV or large R-parity violating terms are considered. In the first case the vacuum is metastable, and different consistency constraints can give a bounded allowed region in the tan β − m{sub susy} plane. In the second case the mass eigenstate electron (down quark) is a linear combination of the original electron (down quark) and Higgsino (heavy colour triplet), and the mass ratio of bino and wino is determined. Both limits lead to light gravitino dark matter.

SUSY: Quo Vadis?

International Nuclear Information System (INIS)

Ross, G.G.

2014-01-01

Given that there is currently no direct evidence for supersymmetric particles at the LHC it is timely to re-evaluate the need for low scale supersymmetry and to ask whether it is likely to be discoverable by the LHC running at its full energy. We review the status of simple SUSY extensions of the Standard Model in the light of the Higgs discovery and the non-observation of evidence for SUSY at the LHC. The need for large radiative corrections to drive the Higgs mass up to 126 GeV and for the coloured SUSY states to be heavy to explain their non-observation introduces a little hierarchy problem and we discuss how to quantify the associated fine tuning. The requirement of low fine tuning requires non-minimal SUSY extensions and we discuss the nature and phenomenology of models which still have perfectly acceptable low fine tuning. A brief discussion of SUSY flavour-changing and CP-violation problems and their resolution is presented. (orig.)

Probes of Yukawa unification in supersymmetric SO(10) models

Energy Technology Data Exchange (ETDEWEB)

Westhoff, Susanne

2009-10-23

This work is composed as follows: In Chapter 1, the disposed reader is made familiar with the foundations of flavourphysics and Grand Unification, including group-theoretical aspects of SO(10). In Chapter 2, we introduce a specific supersymmetric GUT model based on SO(10) and designed to probe down-quark-lepton Yukawa unification. Within this framework we explore the effects of large atmospheric neutrino mixing in bottom-strange transitions on the mass difference and CP phase in B{sub s}- anti B{sub s} meson mixing. Chapter 3 is devoted to corrections to Yukawa unification. We derive constraints on Yukawa corrections for light fermions from K- anti K and B{sub d}- anti B {sub d} mixing. As an application we study implications of neutrino mixing effects in CP-violating K and B{sub d} observables on the unitrity triangle. Finally, in Chapter 4, we discuss effects of large tan {beta} in B{yields}(D){tau}{nu} decays with respect to their potential to discover charged Higgs bosons and to discriminate between different GUT models of flavour.

SUSY Unparticle and Conformal Sequestering

Energy Technology Data Exchange (ETDEWEB)

Nakayama, Yu; Nakayama, Yu

2007-07-17

We investigate unparticle physics with supersymmetry (SUSY). The SUSY breaking effects due to the gravity mediation induce soft masses for the SUSY unparticles and hence break the conformal invariance. The unparticle physics observable in near future experiments is only consistent if the SUSY breakingeffects from the hidden sector to the standard model sector are dominated by the gauge mediation, or if the SUSY breaking effects to the unparticle sector are sufficiently sequestered. We argue that the natural realization of the latter possibility is the conformal sequestering scenario.

Stable SUSY breaking model with O(10) eV gravitino from combined D-term gauge mediation and U(1)' mediation

International Nuclear Information System (INIS)

Nakayama, Yu

2008-01-01

We show a calculable example of stable supersymmetry (SUSY) breaking models with O(10) eV gravitino mass based on the combination of D-term gauge mediation and U(1)' mediation. A potential problem of the negative mass squared for the SUSY standard model (SSM) sfermions in the D-term gauge mediation is solved by the contribution from the U(1)' mediation. On the other hand, the splitting between the SSM gauginos and sfermions in the U(1)' mediation is circumvented by the contributions from the D-term gauge mediation. Since the U(1)' mediation does not introduce any new SUSY vacua, we achieve a completely stable model under thermal effects. Our model, therefore, has no cosmological difficulty

Searches for SUSY at LHC

International Nuclear Information System (INIS)

Kharchilava, A.

1997-01-01

One of the main motivations of experiments at the LHC is to search for SUSY particles. The talk is based on recent analyses, performed by CMS Collaboration, within the framework of the Supergravity motivated minimal SUSY extension of the Standard Model. The emphasis is put on leptonic channels. The strategies for obtaining experimental signatures for strongly and weakly interacting sparticles productions, as well as examples of determination of SUSY masses and model parameters are discussed. The domain of parameter space where SUSY can be discovered is investigated. Results show, that if SUSY is of relevance at Electro-Weak scale it could hardly escape detection at LHC. (author)

R-symmetry violation in N=2 SUSY

International Nuclear Information System (INIS)

Volkov, G.G.; Maslikov, A.A.

1990-01-01

The present paper discusses the spontaneous R-symmetry violation in the N=2 SUSY SU(4)xU(1) model with soft SUSY breaking terms preserving finiteness. (In this case an invisible axion appears). In particular, the mechanism producting a light photino mass up to some GeV is suggested. In R-odd version of this model the mechanisms of enhancement of the neutrino decay is discussed. 10 refs.; 3 figs

A note on local GUT models in F-theory

International Nuclear Information System (INIS)

Chen, C.-M.; Chung, Y.-C.

2010-01-01

We construct non-minimal GUT local models in the F-theory configuration. The gauge group on the bulk G S is one rank higher than the GUT gauge group. The line bundles on the curves are nontrivial to break G S down to the GUT gauge groups. We demonstrate examples of SU(5) GUT from G S =SU(6) and G S =SO(10), the flipped SU(5) from G S =SO(10), and the SO(10) GUT from G S =SO(12) and G S =E 6 . We obtain complete GUT matter spectra and couplings, with minimum exotic matter contents. GUT gauge group breaking to MSSM is achievable by instanton configurations.

Lepton flavor violation from supersymmetric grand unified theories: Where do we stand for MEG, PRISM/PRIME, and a super flavor factory

International Nuclear Information System (INIS)

Calibbi, L.; Faccia, A.; Masiero, A.; Vempati, S. K.

2006-01-01

We analyze the complementarity between lepton flavor violation (LFV) and LHC experiments in probing the supersymmetric (SUSY) grand unified theories (GUT) when neutrinos get a mass via the seesaw mechanism. Our analysis is performed in an SO(10) framework, where at least one neutrino Yukawa coupling is necessarily as large as the top Yukawa coupling. Our study thoroughly takes into account the whole renormalization group running, including the GUT and the right-handed neutrino mass scales, as well as the running of the observable neutrino spectrum. We find that the upcoming (MEG, SuperKEKB) and future (PRISM/PRIME, super flavor factory) LFV experiments will be able to test such SUSY framework for SUSY masses to be explored at the LHC and, in some cases, even beyond the LHC sensitivity reach

Naturalness, SUSY heavy higgses and flavor constraints

CERN Multimedia

CERN. Geneva

2014-01-01

I will demonstrate that supersymmetric (SUSY) higgses provide an important diagnostic for electroweak naturalness in the SUSY paradigm. I first review the naturalness problem of the Standard Model (SM) and SUSY as one of its most promising solutions. I study the masses of heavy Higgses in SUSY theories under broad assumptions, and show how they are constrained by their role in Electroweak symmetry breaking. I then show how Flavor Physics severely constrains large parts of SUSY parameter space, otherwise favored by naturalness. If SUSY Higgses are not discovered at relatively low mass during the next LHC run, this tension will further increase, disfavoring naturalness from SUSY.

Extended tree-level gauge mediation

DEFF Research Database (Denmark)

Monaco, M.; Nardecchia, M.; Romanino, A.

2011-01-01

Tree-level gauge mediation (TGM) is a scenario of SUSY breaking in which the tree-level exchange of heavy (possibly GUT) vector fields generates flavor-universal sfermion masses. In this work we extend this framework to the case of E(6) that is the natural extension of the minimal case studied so...... if the gauge group does not contain SU(5). If SUSY breaking is mediated purely by the U(1) generator that commutes with SO(10) we obtain universal sfermion masses and thus can derive the CMSSM boundary conditions in a novel scenario....

Muon g−2 in anomaly mediated SUSY breaking

International Nuclear Information System (INIS)

Chowdhury, Debtosh; Yokozaki, Norimi

2015-01-01

Motivated by two experimental facts, the muon g−2 anomaly and the observed Higgs boson mass around 125 GeV, we propose a simple model of anomaly mediation, which can be seen as a generalization of mixed modulus-anomaly mediation. In our model, the discrepancy of the muon g−2 and the Higgs boson mass around 125 GeV are easily accommodated. The required mass splitting between the strongly and weakly interacting SUSY particles are naturally achieved by the contribution from anomaly mediation. This model is easily consistent with SU(5) or SO(10) grand unified theory.

Muon g−2 in anomaly mediated SUSY breaking

Energy Technology Data Exchange (ETDEWEB)

Chowdhury, Debtosh; Yokozaki, Norimi [Istituto Nazionale di Fisica Nucleare, Sezione di Roma,Piazzale Aldo Moro 2, I-00185 Rome (Italy)

2015-08-24

Motivated by two experimental facts, the muon g−2 anomaly and the observed Higgs boson mass around 125 GeV, we propose a simple model of anomaly mediation, which can be seen as a generalization of mixed modulus-anomaly mediation. In our model, the discrepancy of the muon g−2 and the Higgs boson mass around 125 GeV are easily accommodated. The required mass splitting between the strongly and weakly interacting SUSY particles are naturally achieved by the contribution from anomaly mediation. This model is easily consistent with SU(5) or SO(10) grand unified theory.

Impact of the muon anomalous magnetic moment on supersymmetric models

International Nuclear Information System (INIS)

Baer, Howard; Balazs, Csaba; Ferrandis, Javier; Tata, Xerxes

2001-01-01

The recent measurement of a μ =(g μ -2)/2 by the E821 Collaboration at Brookhaven deviates from the quoted standard model (SM) central value prediction by 2.6σ. The difference between SM theory and experiment may be easily accounted for in a variety of particle physics models employing weak scale supersymmetry (SUSY). Other supersymmetric models are distinctly disfavored. We evaluate a μ for various supersymmetric models, including minimal supergravity, Yukawa unified SO(10) SUSY GUT's, models with inverted mass hierarchies, models with nonuniversal gaugino masses, gauge mediated SUSY breaking models, anomaly-mediated SUSY breaking models and models with gaugino mediated SUSY breaking. Models with Yukawa coupling unification or multi-TeV first and second generation scalars are disfavored by the a μ measurement

A new family symmetry for SO(10) GUTs

International Nuclear Information System (INIS)

King, Stephen F.; Luhn, Christoph

2009-01-01

We argue that the projective special linear group PSL 2 (7), also known as Σ(168), has unique features which make it the most suitable discrete family symmetry for describing quark and lepton masses and mixing in the framework of SO(10) type unified models. In such models flavon fields in the sextet representation of PSL 2 (7) play a crucial role both in obtaining tri-bimaximal neutrino mixing as well as in generating the third family charged fermion Yukawa couplings. In preparation for physical applications, we derive the triplet representation of PSL 2 (7) in the basis S,T,U,V where S,T,U are the familiar triplet generators of S 4 in the diagonal charged lepton basis where T is diagonal. We also derive an analogous basis for the real sextet representation and identify the vacuum alignments which lead to tri-bimaximal neutrino mixing and large third family charged fermion Yukawa couplings.

Renormalization group running of fermion observables in an extended non-supersymmetric SO(10) model

Energy Technology Data Exchange (ETDEWEB)

Meloni, Davide [Dipartimento di Matematica e Fisica, Università di Roma Tre,Via della Vasca Navale 84, 00146 Rome (Italy); Ohlsson, Tommy; Riad, Stella [Department of Physics, School of Engineering Sciences,KTH Royal Institute of Technology - AlbaNova University Center,Roslagstullsbacken 21, 106 91 Stockholm (Sweden)

2017-03-08

We investigate the renormalization group evolution of fermion masses, mixings and quartic scalar Higgs self-couplings in an extended non-supersymmetric SO(10) model, where the Higgs sector contains the 10{sub H}, 120{sub H}, and 126{sub H} representations. The group SO(10) is spontaneously broken at the GUT scale to the Pati-Salam group and subsequently to the Standard Model (SM) at an intermediate scale M{sub I}. We explicitly take into account the effects of the change of gauge groups in the evolution. In particular, we derive the renormalization group equations for the different Yukawa couplings. We find that the computed physical fermion observables can be successfully matched to the experimental measured values at the electroweak scale. Using the same Yukawa couplings at the GUT scale, the measured values of the fermion observables cannot be reproduced with a SM-like evolution, leading to differences in the numerical values up to around 80%. Furthermore, a similar evolution can be performed for a minimal SO(10) model, where the Higgs sector consists of the 10{sub H} and 126{sub H} representations only, showing an equally good potential to describe the low-energy fermion observables. Finally, for both the extended and the minimal SO(10) models, we present predictions for the three Dirac and Majorana CP-violating phases as well as three effective neutrino mass parameters.

SUSY Searches at ATLAS

CERN Document Server

Mamuzic, Judita; The ATLAS collaboration

2017-01-01

Supersymmetry (SUSY) is considered one of the best motivated extensions of the Standard Model. It postulates a fundamental symmetry between fermions and bosons, and introduces a set of new supersymmetric particles at the electroweak scale. It addresses the hierarchy and naturalness problem, gives a solution to the gauge coupling unification, and offers a cold dark matter candidate. Different aspects of SUSY searches, using strong, electroweak, third generation production, and R-parity violation and long lived particles are being studied at the LHC. An overview of most recent SUSY searches results using the 13 TeV ATLAS RUN2 data will be presented.

The Higgs boson mass and SUSY spectra in 10D SYM theory with magnetized extra dimensions

Directory of Open Access Journals (Sweden)

Hiroyuki Abe

2014-11-01

Full Text Available We study the Higgs boson mass and the spectrum of supersymmetric (SUSY particles in the well-motivated particle physics model derived from a ten-dimensional supersymmetric Yang–Mills theory compactified on three factorizable tori with magnetic fluxes. This model was proposed in a previous work, where the flavor structures of the standard model including the realistic Yukawa hierarchies are obtained from non-hierarchical input parameters on the magnetized background. Assuming moduli- and anomaly-mediated contributions dominate the soft SUSY breaking terms, we study the precise SUSY spectra and analyze the Higgs boson mass in this mode, which are compared with the latest experimental data.

SUSY naturalness without prejudice

CERN Document Server

Ghilencea, D M

2014-01-01

Unlike the Standard Model (SM), supersymmetric models stabilize the electroweak (EW) scale $v$ at the quantum level and {\\it predict} that $v$ is a function of the TeV-valued SUSY parameters ($\\gamma_\\alpha$) of the UV Lagrangian. We show that the (inverse of the) covariance matrix of the model in the basis of these parameters and the usual deviation $\\delta\\chi^2$ (from $\\chi^2_{min}$ of a model) automatically encode information about the "traditional" EW fine-tuning measuring this stability, {\\it provided that} the EW scale $v\\sim m_Z$ is indeed regarded as a function $v=v(\\gamma)$. It is known that large EW fine-tuning may signal an incomplete theory of soft terms and can be reduced when relations among $\\gamma_\\alpha$ exist (due to GUT symmetries, etc). The global correlation coefficient of this matrix can help one investigate if such relations are present. An upper bound on the usual EW fine-tuning measure ("in quadrature") emerges from the analysis of the $\\delta\\chi^2$ and the s-standard deviation conf...

Radiative see-saw formula in nonsupersymmetric SO (10) with dark ...

Indian Academy of Sciences (India)

In the absence of supersymmetry, we show how experimentally verifiable radiative see-saw formula of Ma type is realized in non-SUSY (10) while fulfilling the twin objectives: precision gauge coupling unification and dark matter. This model is expected to have a dramatic impact on neutrino physics, dark matter and all ...

Testing SUSY

CERN Document Server

Cassel, S; Ross, G G

2010-01-01

If SUSY provides a solution to the hierarchy problem then supersymmetric states should not be too heavy. This requirement is quantified by the Barbieri-Giudice fine tuning measure that provides a quantitative test of SUSY as a solution to the hierarchy problem. The measure is useful in correlating the impact of the various experimental measurements relevant to the search for supersymmetry and also in identifying the most sensitive measurements for testing SUSY. In this paper we apply the measure to the CMSSM, computing it to two-loop order and taking account of current experimental limits and the constraint on dark matter abundance. Using this we determine the present limits on the CMSSM parameter space and identify the measurements at the LHC that are most significant in covering the remaining parameter space. Without imposing the LEP Higgs mass bound we show that the smallest fine tuning (1:14.5) consistent with a saturation of the relic density within the 1$\\sigma$ WMAP bounds corresponds to a Higgs mass o...

SUSY Searches at ATLAS and CMS

CERN Document Server

Urquijo, P; The ATLAS collaboration

2009-01-01

We review the current strategies to search for Supersymmetry (SUSY) with the ATLAS and CMS detectors at the LHC. The early data discovery potential will be presented for search channels based on missing transverse momentum from undetected neutralinos and multiple high transverse momentum jets. We describe the search for models of gauge-mediated SUSY breaking for which the next to lightest SUSY particle is a neutralino that decays into a photon and gravitino. Examples of measurement techniques that probe the SUSY mass scale in the first data, through reconstruction of kinematic endpoints, are also shown.

B-L mediated SUSY breaking with radiative B-L symmetry breaking

International Nuclear Information System (INIS)

Kikuchi, Tatsuru; Kubo, Takayuki

2008-01-01

We explore a mechanism of radiative B-L symmetry breaking in analogous to the radiative electroweak symmetry breaking. The breaking scale of B-L symmetry is related to the neutrino masses through the see-saw mechanism. Once we incorporate the U(1) B-L gauge symmetry in SUSY models, the U(1) B-L gaugino, Z-tilde B-L appears, and it can mediate the SUSY breaking (Z-prime mediated SUSY breaking) at around the scale of 10 6 GeV. Then we find a links between the neutrino mass (more precisly the see-saw or B-L scale of order 10 6 GeV) and the Z-prime mediated SUSY breaking scale. It is also very interesting that the gluino at the weak scale becomes relatively light, and almost compressed mass spectra for the gaugino sector can be realized in this scenario, which is very interesting in scope of the LHC.

Can the ''doublet-triplet splitting'' problem be solved without doublet-triplet splitting?

International Nuclear Information System (INIS)

Dvali, G.R.

1992-03-01

We consider a new possible mechanism for the natural solution of the doublet-triplet splitting problem in SUSY GUTs. In contrast to the usually discussed scenarios, in our case the GUT symmetry breaking does not provide any splitting between the Higgs doublet and the triplet masses. The weak doublet and its colour triplet partner both remain light, but the triplet automatically occurs decoupled from the quark and lepton superfields and cannot induce proton decay. The advantage of the above scenarios is the absence at the GUT scale of the baryon number violating the tree level d = 5 and d = 6 operators via the colour-triple exchange. It is shown that in flipped SU(5) GUT they do not appear at any scale. In the SO(10) model, such operators can be induced after SUSY breaking but are strongly suppressed. (author). 22 refs, 2 figs

Susy and Such

International Nuclear Information System (INIS)

Dawson, S.

1997-01-01

In these lectures, the author discusses the theoretical motivation for supersymmetric theories and introduce the minimal low energy effective supersymmetric theory, (MSSM). I consider only the MSSM and its simplest grand unified extension here. Some of the other possible low-energy SUSY models are summarized. The particles and their interactions are examined in detail in the next sections and a grand unified SUSY model presented which gives additional motivation for pursuing supersymmetric theories

Simplified SUSY at the ILC

International Nuclear Information System (INIS)

Berggren, Mikael

2013-08-01

At the ILC, one has the possibility to search for SUSY in an model-independent way: The corner-stone of SUSY is that sparticles couple as particles. This is independent of the mechanism responsible for SUSY breaking. Any model will have one Lightest SUSY Particle (LSP), and one Next to Lightest SUSY Particle (NLSP). In models with conserved R-parity, the NLSP must decay solely to the LSP and the SM partner of the NLSP. Therefore, studying NLSP production and decay can be regarded as a ''simplified model without simplification'': Any SUSY model will have such a process. The NLSP could be any sparticle: a slepton, an electroweak-ino, or even a squark. However, since there are only a finite number of sparticles, one can systematically search for signals of all possible NLSP:s. This way, the entire space of models that have a kinematically reachable NLSP can be covered. For any NLSP, the ''worst case'' can be determined, since the SUSY principle allows to calculate the cross-section once the NLSP nature and mass are given. The region in the LSP-NLSP mass-plane where the ''worst case'' could be discovered or excluded experimentally can be found by estimating background and efficiency at each point in the plane. From experience at LEP, it is expected that the lower signal-to background ratio will indeed be found for models with conserved R-parity. In this document, we show that at the ILC, such a program is possible, as it was at LEP. No loop-holes are left, even for difficult or non-standard cases: whatever the NLSP is it will be detectable.

Simplified SUSY at the ILC

Energy Technology Data Exchange (ETDEWEB)

Berggren, Mikael

2013-08-15

At the ILC, one has the possibility to search for SUSY in an model-independent way: The corner-stone of SUSY is that sparticles couple as particles. This is independent of the mechanism responsible for SUSY breaking. Any model will have one Lightest SUSY Particle (LSP), and one Next to Lightest SUSY Particle (NLSP). In models with conserved R-parity, the NLSP must decay solely to the LSP and the SM partner of the NLSP. Therefore, studying NLSP production and decay can be regarded as a ''simplified model without simplification'': Any SUSY model will have such a process. The NLSP could be any sparticle: a slepton, an electroweak-ino, or even a squark. However, since there are only a finite number of sparticles, one can systematically search for signals of all possible NLSP:s. This way, the entire space of models that have a kinematically reachable NLSP can be covered. For any NLSP, the ''worst case'' can be determined, since the SUSY principle allows to calculate the cross-section once the NLSP nature and mass are given. The region in the LSP-NLSP mass-plane where the ''worst case'' could be discovered or excluded experimentally can be found by estimating background and efficiency at each point in the plane. From experience at LEP, it is expected that the lower signal-to background ratio will indeed be found for models with conserved R-parity. In this document, we show that at the ILC, such a program is possible, as it was at LEP. No loop-holes are left, even for difficult or non-standard cases: whatever the NLSP is it will be detectable.

Cornering natural SUSY at LHC Run II and beyond

Science.gov (United States)

Buckley, Matthew R.; Feld, David; Macaluso, Sebastian; Monteux, Angelo; Shih, David

2017-08-01

We derive the latest constraints on various simplified models of natural SUSY with light higgsinos, stops and gluinos, using a detailed and comprehensive reinterpretation of the most recent 13 TeV ATLAS and CMS searches with ˜ 15 fb-1 of data. We discuss the implications of these constraints for fine-tuning of the electroweak scale. While the most "vanilla" version of SUSY (the MSSM with R-parity and flavor-degenerate sfermions) with 10% fine-tuning is ruled out by the current constraints, models with decoupled valence squarks or reduced missing energy can still be fully natural. However, in all of these models, the mediation scale must be extremely low ( model-building directions for natural SUSY that are motivated by this work.

RPV SUSY searches at ATLAS and CMS

CERN Document Server

Pettersson, Nora Emilia; The ATLAS collaboration

2015-01-01

Experimental searches for Supersymmetry (SUSY) at the Large Hadronic Collider (LHC) often assume R-Parity Conservation (RPC) to avoid proton decay. A consequence RPC is that it implies a stable SUSY-particle that cannot decay. The search strategies are strongly based on the hypothesize of weakly interacting massive particles escaping without detection - yielding missing transverse energy (MET) to the collision events. It is vital to explore all possibilities considering that no observation of SUSY has been made and that strong exclusions already have been placed on RPC-SUSY scenarios. Introducing individually baryon- and lepton-number violating couplings in R-Parity Violating (RPV) models would avoid rapid proton decay. The strong mass and cross-section exclusion set for RPC-SUSY are weaken if RPV couplings are allowed in the SUSY Lagrangian - as these standard searches lose sensitivity due to less expected MET. This talk aims to summarise a few of the experimental searches for both prompt and long-lived RPV ...

Neutrino masses from SUSY breaking in radiative seesaw models

International Nuclear Information System (INIS)

Figueiredo, Antonio J.R.

2015-01-01

Radiatively generated neutrino masses (m ν ) are proportional to supersymmetry (SUSY) breaking, as a result of the SUSY non-renormalisation theorem. In this work, we investigate the space of SUSY radiative seesaw models with regard to their dependence on SUSY breaking (SUSY). In addition to contributions from sources of SUSY that are involved in electroweak symmetry breaking (SUSY EWSB contributions), and which are manifest from left angle F H † right angle = μ left angle anti H right angle ≠ 0 and left angle D right angle = g sum H left angle H † x H H right angle ≠ 0, radiatively generated m ν can also receive contributions from SUSY sources that are unrelated to EWSB (SUSY EWS contributions). We point out that recent literature overlooks pure-SUSY EWSB contributions (∝ μ/M) that can arise at the same order of perturbation theory as the leading order contribution from SUSY EWS . We show that there exist realistic radiative seesaw models in which the leading order contribution to m ν is proportional to SUSY EWS . To our knowledge no model with such a feature exists in the literature. We give a complete description of the simplest model topologies and their leading dependence on SUSY. We show that in one-loop realisations LLHH operators are suppressed by at least μ m soft /M 3 or m soft 2 /M 3 . We construct a model example based on a oneloop type-II seesaw. An interesting aspect of these models lies in the fact that the scale of soft-SUSY effects generating the leading order m ν can be quite small without conflicting with lower limits on the mass of new particles. (orig.)

Radiative breaking scenario for the GUT gauge symmetry

International Nuclear Information System (INIS)

Fukuyama, T.; Kikuchi, T.

2006-01-01

The origin of the grand unified theory (GUT) scale from the top-down perspective is explored. The GUT gauge symmetry is broken by the renormalization group effects, which is an extension of the radiative electroweak symmetry breaking scenario to the GUT models. That is, in the same way as the origin of the electroweak scale, the GUT scale is generated from the Planck scale through the radiative corrections to the soft supersymmetry breaking mass parameters. This mechanism is applied to a perturbative SO(10) GUT model, recently proposed by us. In the SO(10) model, the relation between the GUT scale and the Planck scale can naturally be realized by using order-one coupling constants. (orig.)

Recent SUSY results in ATLAS

CERN Document Server

Mamuzic, Judita; The ATLAS collaboration

2018-01-01

Supersymmetry (SUSY) is considered one of the best motivated extensions of the Standard Model. It postulates a fundamental symmetry between fermions and bosons, and introduces a set of new supersymmetric particles at the electroweak scale. It addresses the hierarchy and natu- ralness problem, gives a solution to the gauge couplings unification, and offers a cold dark matter candidate. Different aspects of SUSY searches, using strong, electroweak, third generation production, R-parity violation models, and long lived particles are being studied at the LHC. An overview of most recent results in SUSY searches using Run 2 ATLAS data, at 13 TeV with 36.1 fb−1 of integrated luminosity, was presented.

Higgs, Binos and Gluinos: Split Susy within Reach

Energy Technology Data Exchange (ETDEWEB)

Alves, Daniele S.M.; Izaguirre, Eder; /SLAC /Stanford U., Phys. Dept.; Wacker, Jay G.; /SLAC /Stanford U., ITP

2012-09-14

Recent results from the LHC for the Higgs boson with mass between 142 GeV {approx}< m{sub h{sup 0}} {approx}< 147 GeV points to PeV-scale Split Supersymmetry. This article explores the consequences of a Higgs mass in this range and possible discovery modes for Split Susy. Moderate lifetime gluinos, with decay lengths in the 25 {micro}m to 10 yr range, are its imminent smoking gun signature. The 7TeV LHC will be sensitive to the moderately lived gluinos and trilepton signatures from direct electroweakino production. Moreover, the dark matter abundance may be obtained from annihilation through an s-channel Higgs resonance, with the LSP almost purely bino and mass m{sub {chi}{sub 1}{sup 0}} {approx_equal} 70 GeV. The Higgs resonance region of Split Susy has visible signatures in dark matter direct and indirect detection and electric dipole moment experiments. If the anomalies go away, the majority of Split Susy parameter space will be excluded.

Natural SUSY endures

Energy Technology Data Exchange (ETDEWEB)

Papucci, Michele; Ruderman, Joshua T. [Lawrence Berkeley National Laboratory, CA (United States). Theoretical Physics Group; California Univ., Berkeley, CA (United States). Dept. of Physics; Weiler, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); European Organization for Nuclear Research, Geneva (Switzerland). Theoretical Physics Div.

2011-10-31

The first 1 fb{sup -1} of LHC searches have set impressive limits on new colored particles decaying to missing energy. We address the implication of these searches for naturalness in supersymmetry (SUSY). General bottom-up considerations of natural electroweak symmetry breaking show that higgsinos, stops, and the gluino should not be too far above the weak scale. The rest of the spectrum, including the squarks of the first two generations, can be heavier and beyond the current LHC reach. We have used collider simulations to determine the limits that all of the 1 fb{sup -1} searches pose on higgsinos, stops, and the gluino. We find that stops and the left-handed sbottom are starting to be constrained and must be heavier than about 200-300 GeV when decaying to higgsinos. The gluino must be heavier than about 600-800 GeV when it decays to stops and sbottoms. While these findings point toward scenarios with a lighter third generation split from the other squarks, we do find that moderately-tuned regions remain, where the gluino is just above 1 TeV and all the squarks are degenerate and light. Among all the searches, jets plus missing energy and same-sign dileptons often provide the most powerful probes of natural SUSY. Overall, our results indicate that natural SUSY has survived the first 1 fb{sup -1} of data. The LHC is now on the brink of exploring the most interesting region of SUSY parameter space. (orig.)

Yukawa unification in moduli-dominant SUSY breaking

International Nuclear Information System (INIS)

Khalil, S.; Tatsuo Kobayashi

1997-07-01

We study Yukawa in string models with moduli-dominant SUSY breaking. This type of SUSY breaking in general leads to non-universal soft masses, i.e. soft scalar masses and gaugino masses. Such non-universality is important for phenomenological aspects of Yukawa unification, i.e., successful electroweak breaking, SUSY corrections to the bottom mass and the branching ratio of b → sγ. We show three regions in the whole parameter space which lead to successful electroweak breaking and allow small SUSY corrections to the bottom mass. For these three regions we investigated the b → sγ decay and mass spectra. (author). 26 refs, 6 figs

Kaehler geometry and SUSY mechanics

International Nuclear Information System (INIS)

Bellucci, Stefano; Nersessian, Armen

2001-01-01

We present two examples of SUSY mechanics related with Kaehler geometry. The first system is the N = 4 supersymmetric one-dimensional sigma-model proposed in hep-th/0101065. Another system is the N = 2 SUSY mechanics whose phase space is the external algebra of an arbitrary Kaehler manifold. The relation of these models with antisymplectic geometry is discussed

On SUSY inspired minimal lepton number violation

International Nuclear Information System (INIS)

Chkareuli, J.L.; Gogoladze, I.G.; Green, M.G.; Hutchroft, D.E.; Kobakhidze, A.B.

2000-03-01

A minimal lepton number violation (LNV) is proposed which could naturally appear in SUSY theories, if Yukawa and LNV couplings had a common origin. According to this idea properly implemented into MSSM with an additional abelian flavor symmetry the prototype LNV appears due to a mixing of leptons with superheavy Higgs doublet mediating Yukawa couplings. As a result, all significant physical manifestations of LNV reduce to those of the effective trilinear couplings LLE-bar and LQD-bar aligned, by magnitude and orientation in a flavor space, with the down fermion (charged lepton and down quark) effective Yukawa couplings, while the effective bilinear terms appear generically suppressed relative to an ordinary μ-term of MSSM. Detailed phenomenology of the model related to the flavor-changing processes both in quark and lepton sectors, radiatively induced neutrino masses and decays of the LSP is presented. Remarkably, the model can straightforwardly be extended to a Grand Unified framework and an explicit example with SU(7) GUT is thoroughly discussed. (author)

SUSY naturalness without prejudice

Science.gov (United States)

Ghilencea, D. M.

2014-05-01

Unlike the Standard Model (SM), supersymmetric models stabilize the electroweak (EW) scale v at the quantum level and predict that v is a function of the TeV-valued SUSY parameters (γα) of the UV Lagrangian. We show that the (inverse of the) covariance matrix of the model in the basis of these parameters and the usual deviation δχ2 (from χmin2 of a model) automatically encode information about the "traditional" EW fine-tuning measuring this stability, provided that the EW scale v ˜mZ is indeed regarded as a function v =v(γ). It is known that large EW fine-tuning may signal an incomplete theory of soft terms and can be reduced when relations among γα exist (due to GUT symmetries, etc.). The global correlation coefficient of this matrix can help one investigate if such relations are present. An upper bound on the usual EW fine-tuning measure ("in quadrature") emerges from the analysis of the δχ2 and the s-standard deviation confidence interval by using v =v(γ) and the theoretical approximation (loop order) considered for the calculation of the observables. This upper bound avoids subjective criteria for the "acceptable" level of EW fine-tuning for which the model is still "natural."

Implications for new physics from fine-tuning arguments 1. Application to SUSY and seesaw cases

International Nuclear Information System (INIS)

Alberto Casas, J.; Hidalgo, Irene; Espinosa, Jose R.

2004-01-01

We revisit the standard argument to estimate the scale of new physics (NP) beyond the SM, based on the sensitivity of the Higgs mass to quadratic divergences. Although this argument is arguably naive, the corresponding estimate, Λ SM SM . One can obtain more precise implications from fine-tuning arguments in specific examples of NP. Here we consider SUSY and right-handed (seesaw) neutrinos. SUSY is a typical example for which the previous general estimate is indeed conservative: the MSSM is fine-tuned a few %, even for soft masses of a few hundred GeV. In contrast, other SUSY scenarios, in particular those with low-scale SUSY breaking, can easily saturate the general bound on Λ SM . The seesaw mechanism requires large fine-tuning if M R > or approx.10 7 GeV, unless there is additional NP (SUSY being a favourite option). (author)

Peccei-Quinn invariant singlet extended SUSY with anomalous U(1) gauge symmetry

Energy Technology Data Exchange (ETDEWEB)

Im, Sang Hui; Seo, Min-Seok [Center for Theoretical Physics of the Universe, Institute for Basic Science (IBS),Daejeon 305-811 (Korea, Republic of)

2015-05-13

Recent discovery of the SM-like Higgs boson with m{sub h}≃125 GeV motivates an extension of the minimal supersymmetric standard model (MSSM), which involves a singlet Higgs superfield with a sizable Yukawa coupling to the doublet Higgs superfields. We examine such singlet-extended SUSY models with a Peccei-Quinn (PQ) symmetry that originates from an anomalous U(1){sub A} gauge symmetry. We focus on the specific scheme that the PQ symmetry is spontaneously broken at an intermediate scale v{sub PQ}∼√(m{sub SUSY}M{sub Pl}) by an interplay between Planck scale suppressed operators and tachyonic soft scalar mass m{sub SUSY}∼√(D{sub A}) induced dominantly by the U(1){sub A}D-term D{sub A}. This scheme also results in spontaneous SUSY breaking in the PQ sector, generating the gaugino masses M{sub 1/2}∼√(D{sub A}) when it is transmitted to the MSSM sector by the conventional gauge mediation mechanism. As a result, the MSSM soft parameters in this scheme are induced mostly by the U(1){sub A}D-term and the gauge mediated SUSY breaking from the PQ sector, so that the sparticle masses can be near the present experimental bounds without causing the SUSY flavor problem. The scheme is severely constrained by the condition that a phenomenologically viable form of the low energy operators of the singlet and doublet Higgs superfields is generated by the PQ breaking sector in a way similar to the Kim-Nilles solution of the μ problem, and the resulting Higgs mass parameters allow the electroweak symmetry breaking with small tan β. We find two minimal models with two singlet Higgs superfields, satisfying this condition with a relatively simple form of the PQ breaking sector, and briefly discuss some phenomenological aspects of the model.

Optimization of Markov chains for a SUSY fitter: Fittino

Energy Technology Data Exchange (ETDEWEB)

Prudent, Xavier [IKTP, Technische Universitaet, Dresden (Germany); Bechtle, Philip [DESY, Hamburg (Germany); Desch, Klaus; Wienemann, Peter [Universitaet Bonn (Germany)

2010-07-01

A Markov chains is a ''random walk'' algorithm which allows an efficient scan of a given profile and the search of the absolute minimum, even when this profil suffers from the presence of many secondary minima. This property makes them particularly suited to the study of Supersymmetry (SUSY) models, where minima have to be found in up-to 18-dimensional space for the general MSSM. Hence the SUSY fitter ''Fittino'' uses a Metropolis*Hastings Markov chain in a frequentist interpretation to study the impact of current low -energy measurements, as well as expected measurements from LHC and ILC, on the SUSY parameter space. The expected properties of an optimal Markov chain should be the independence of final results with respect to the starting point and a fast convergence. These two points can be achieved by optimizing the width of the proposal distribution, that is the ''average step length'' between two links in the chain. We developped an algorithm for the optimization of the proposal width, by modifying iteratively the width so that the rejection rate be around fifty percent. This optimization leads to a starting point independent chain as well as a faster convergence.

SUSY Without Prejudice at Linear Colliders

International Nuclear Information System (INIS)

Rizzo, T.

2008-01-01

We explore the physics of the general CP-conserving MSSM with Minimal Flavor Violation, the pMSSM. The 19 soft SUSY breaking parameters are chosen so to satisfy all existing experimental and theoretical constraints assuming that the WIMP is the lightest neutralino. We scan this parameter space twice using both flat and log priors and compare the results which yield similar conclusions. Constraints from both LEP and the Tevatron play an important role in obtaining our final model samples. Implications for future TeV-scale e + e - linear colliders (LC) are discussed

Lifshitz-sector mediated SUSY breaking

OpenAIRE

Pospelov, MaximDepartment of Physics and Astronomy, University of Victoria, Victoria, BC, V8P 5C2, Canada; Tamarit, Carlos(Perimeter Institute for Theoretical Physics, Waterloo, ON, N2L 2Y5, Canada)

2014-01-01

We propose a novel mechanism of SUSY breaking by coupling a Lorentz-invariant supersymmetric matter sector to non-supersymmetric gravitational interactions with Lifshitz scaling. The improved UV properties of Lifshitz propagators moderate the otherwise uncontrollable ultraviolet divergences induced by gravitational loops. This ensures that both the amount of induced Lorentz violation and SUSY breaking in the matter sector are controlled by $ {{{\\Lambda_{\\mathrm{HL}}^2}} \\left/ {{M_P^2}} \\righ...

SUSY particles

CERN Document Server

Nath, Pran

1994-01-01

Analysis of the SUSY spectrum in supergravity unified models is given under the naturalness criterion that the universal scalar mass (m_0) and the gluino mass (m_{\\tilde g}) satisfy the constraint m_0, m_{\\tilde g} less than or equal to 1 TeV. The SUSY spectrum is analysed in four different scenarios: (1) minimal supergravity models ignoring proton decay from dimension five operators, (2) imposing proton stability constraint in supergravity models with SU(5) type embedding which allow proton decay via dimension five operators, (3) with inclusion of dark matter constraints in models of type (1), and (4) with inclusion of dark matter constraint in models of type (2). It is found that there is a very strong upper limit on the light chargino mass in models of type (4), i.e., the light chargino mass is less than or equals 120 GeV.

Status of the SUSY Les Houches Accord II Project

International Nuclear Information System (INIS)

Allanch, B.C.; Balazs, C.; Belanger, G.; Boudjema, F.; Choudhury, D.; Desch, K.; Ellwanger, U.; Gambino, P.; Godbole, R.; Guasch, J.; Guchait, M.; Heinemeyer, S.; Hugonie, C.; Hurth, T.; Kraml, S.; Lykken, J.; Mangano, M.; Moortgat, F.; Moretti, S.; Penaranda, S.; Porod, W.; Fermilab

2005-01-01

Supersymmetric (SUSY) spectrum generators, decay packages, Monte-Carlo programs, dark matter evaluators, and SUSY fitting programs often need to communicate in the process of an analysis. The SUSY Les Houches Accord provides a common interface that conveys spectral and decay information between the various packages. Here, we propose extensions of the conventions of the first SUSY Les Houches Accord to include various generalizations: violation of CP, R-parity and flavor as well as the simplest next-to-minimal supersymmetric standard model (NMSSM)

R-Parity Violating SUSY Results from ATLAS and CMS

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00360876; The ATLAS collaboration

2016-01-01

Experimental searches for Supersymmetry (SUSY) at the Large Hadronic Collider (LHC) often assume R-Parity Conservation (RPC) to avoid proton decay. A consequence of RPC is that it implies the existence of a stable SUSY-particle that cannot decay. The search strategies are strongly based on the hypothesize of weakly interacting massive particles escaping without detection - yielding missing transverse energy (MET) to the collision events. It is vital to explore all possibilities considering that no observation of SUSY has been made and that strong exclusions already have been placed on RPC-SUSY scenarios. Introducing individually baryon- and lepton-number violating couplings in R-Parity Violating (RPV) models would avoid rapid proton decay. The strong mass and cross-section exclusion set for RPC-SUSY are weaken if RPV couplings are allowed in the SUSY Lagrangian - as these standard searches lose sensitivity due to less expected MET. A summarization a few of the experimental searches for both prompt and long-li...

Search for non-standard SUSY signatures in CMS

International Nuclear Information System (INIS)

Teyssier, Daniel

2008-01-01

New studies of the CMS collaboration are presented on the sensitivity to searches for non-standard signatures of particular SUSY scenarios. These signatures include non-pointing photons as well as pairs of prompt photons as expected GMSB SUSY models, as well as heavy stable charged particles produced in split supersymmetry models, long lived staus from GMSB SUSY and long lived stops in other SUSY scenarios. Detailed detector simulation is used for the study, and all relevant Standard Model background and detector effects that can mimic these special signatures are included. It is shown that with already with less than 100 pb -1 the CMS sensitivity will probe an interesting as yet by data unexplored parameter range of these models.

Lifshitz-sector mediated SUSY breaking

International Nuclear Information System (INIS)

Pospelov, Maxim; Tamarit, Carlos

2014-01-01

We propose a novel mechanism of SUSY breaking by coupling a Lorentz-invariant supersymmetric matter sector to non-supersymmetric gravitational interactions with Lifshitz scaling. The improved UV properties of Lifshitz propagators moderate the otherwise uncontrollable ultraviolet divergences induced by gravitational loops. This ensures that both the amount of induced Lorentz violation and SUSY breaking in the matter sector are controlled by Λ HL 2 /M P 2 , the ratio of the Hořava-Lifshitz cross-over scale Λ HL to the Planck scale M P . This ratio can be kept very small, providing a novel way of explicitly breaking supersymmetry without reintroducing fine-tuning. We illustrate our idea by considering a model of scalar gravity with Hořava-Lifshitz scaling coupled to a supersymmetric Wess-Zumino matter sector, in which we compute the two-loop SUSY breaking corrections to the masses of the light scalars due to the gravitational interactions and the heavy fields

Results from GRACE/SUSY at one-loop

Indian Academy of Sciences (India)

We report the recent development on the SUSY calculations with the help of GRACE system. GRACE/SUSY/1LOOP is the computer code which can generate Feynman diagrams in the MSSM automatically and compute one-loop amplitudes in the numerical way. We present new results of various two-body decay widths ...

Supersymmetry Searches in GUT Models with Non-Universal Scalar Masses

CERN Document Server

Cannoni, M.; Gómez, M.E.; Lola, S.; Ruiz de Austri, R.

2016-03-22

We study SO(10), SU(5) and flipped SU(5) GUT models with non-universal soft supersymmetry-breaking scalar masses, exploring how they are constrained by LHC supersymmetry searches and cold dark matter experiments, and how they can be probed and distinguished in future experiments. We find characteristic differences between the various GUT scenarios, particularly in the coannihilation region, which is very sensitive to changes of parameters. For example, the flipped SU(5) GUT predict the possibility of $\\tilde{t}_1-\\chi$ coannihilation, which is absent in the regions of the SO(10) and SU(5) GUT parameter spaces that we study. We use the relic density predictions in different models to determine upper bounds for the neutralino masses, and we find large differences between different GUT models in the sparticle spectra for the same LSP mass, leading to direct connections of distinctive possible experimental measurements with the structure of the GUT group. We find that future LHC searches for generic missing $E_T$...

Searches for Electroweak SUSY by ATLAS and CMS

CERN Document Server

Khoo, Teng Jian; The ATLAS collaboration

2018-01-01

While strongly-produced SUSY and third-generation squark searches have already breached the TeV mass range, direct production of electroweak gauginos is less tightly constrained. New searches are presented, showcasing novel strategies for filling in the gaps in sensitivity to electroweak SUSY at ATLAS and CMS.

Electroweak SUSY production searches at ATLAS and CMS

CERN Document Server

Flowerdew, M; The ATLAS collaboration

2014-01-01

The discovery of weak-scale supersymmetric (SUSY) particles is one of the primary goals of the Large Hadron Collider experiments. Depending on the mechanism of SUSY breaking, it could be that strongly interacting squarks and gluinos are too massive to produce at the LHC. In this case, the primary SUSY production mode is of charginos, neutralinos and sleptons, mediated by electroweak interactions. However, the experimental signatures for discovery vary widely, depending on the mass hierarchy, SUSY particle mixing parameters and conservation/violation of R-parity, necessitating a large and complex suite of experimental search strategies. These strategies include searching for events with multiple charged leptons, photons, reconstructed higgs bosons or new long-lived particles. In this presentation, the latest ATLAS and CMS search results in these channels are presented, based mainly on $20~$fb$^{-1}$ of $pp$ collisions at $\\sqrt{s} = 8~$TeV collected in 2012. The resulting constraints on the parameter spaces of...

EW SUSY production searches at ATLAS and CMS

CERN Document Server

Flowerdew, MJ; The ATLAS collaboration

2014-01-01

The discovery of weak-scale supersymmetric (SUSY) particles is one of the primary goals of the Large Hadron Collider experiments. Depending on the mechanism of SUSY breaking, it could be that strongly interacting squarks and gluinos are too massive to produce at the LHC. In this case, the primary SUSY production mode is of charginos, neutralinos and sleptons, mediated by electroweak interactions. However, the experimental signatures for discovery vary widely, depending on the mass hierarchy, SUSY particle mixing parameters and conservation/violation of R-parity, necessitating a large and complex suite of experimental search strategies. These strategies include searching for events with multiple charged leptons, photons, reconstructed higgs bosons or new long-lived particles. In this presentation, the latest ATLAS and CMS search results in these channels are presented, based mainly on 20 fb$^{-1}$ of pp collisions at $\\sqrt{s} = 8$ TeV collected in 2012. The resulting constraints on the parameter spaces of var...

Prospects for axion detection in natural SUSY with mixed axion-higgsino dark matter: back to invisible?

Energy Technology Data Exchange (ETDEWEB)

Bae, Kyu Jung [Center for Theoretical Physics of the Universe, Institute for Basic Science (IBS), Daejeon 34051 (Korea, Republic of); Baer, Howard; Serce, Hasan, E-mail: kyujungbae@ibs.re.kr, E-mail: baer@nhn.ou.edu, E-mail: serce@ou.edu [Department of Physics and Astronomy, University of Oklahoma, Norman, OK 73019 (United States)

2017-06-01

Under the expectation that nature is natural, we extend the Standard Model to include SUSY to stabilize the electroweak sector and PQ symmetry to stabilize the QCD sector. Then natural SUSY arises from a Kim-Nilles solution to the SUSY μ problem which allows for a little hierarchy where μ∼ f {sub a} {sup 2}/ M {sub P} {sub ∼} 100−300 GeV while the SUSY particle mass scale m {sub SUSY}∼ 1−10 TeV >> μ. Dark matter then consists of two particles: a higgsino-like WIMP and a SUSY DFSZ axion. The range of allowed axion mass values m {sub a} depends on the mixed axion-higgsino relic density. The range of m {sub a} is actually restricted in this case by limits on WIMPs from direct and indirect detection experiments. We plot the expected axion detection rate at microwave cavity experiments. The axion-photon-photon coupling is severely diminished by charged higgsino contributions to the anomalous coupling. In this case, the axion may retreat, at least temporarily, back into the regime of near invisibility. From our results, we urge new ideas for techniques which probe both deeper and more broadly into axion coupling versus axion mass parameter space.

What is a natural SUSY scenario?

Energy Technology Data Exchange (ETDEWEB)

Casas, J. Alberto; Moreno, Jesús M.; Robles, Sandra; Rolbiecki, Krzysztof [Instituto de Física Teórica, IFT-UAM/CSIC, Universidad Autónoma de Madrid,Cantoblanco, 28049 Madrid (Spain); Zaldívar, Bryan [Service de Physique Théorique, Université Libre de Bruxelles,Boulevard du Triomphe, CP225, 1050 Brussels (Belgium)

2015-06-11

The idea of “Natural SUSY', understood as a supersymmetric scenario where the fine-tuning is as mild as possible, is a reasonable guide to explore supersymmetric phenomenology. In this paper, we re-examine this issue in the context of the MSSM including several improvements, such as the mixing of the fine-tuning conditions for different soft terms and the presence of potential extra fine-tunings that must be combined with the electroweak one. We give tables and plots that allow to easily evaluate the fine-tuning and the corresponding naturalness bounds for any theoretical model defined at any high-energy (HE) scale. Then, we analyze in detail the complete fine-tuning bounds for the unconstrained MSSM, defined at any HE scale. We show that Natural SUSY does not demand light stops. Actually, an average stop mass below 800 GeV is disfavored, though one of the stops might be very light. Regarding phenomenology, the most stringent upper bound from naturalness is the one on the gluino mass, which typically sets the present level fine-tuning at O(1%). However, this result presents a strong dependence on the HE scale. E.g. if the latter is 10{sup 7} GeV the level of fine-tuning is ∼ four times less severe. Finally, the most robust result of Natural SUSY is by far that Higgsinos should be rather light, certainly below 700 GeV for a fine-tuning of O(1%) or milder. Incidentally, this upper bound is not far from ≃1 TeV, which is the value required if dark matter is made of Higgsinos.

Early universe cosmology. In supersymmetric extensions of the standard model

International Nuclear Information System (INIS)

Baumann, Jochen Peter

2012-01-01

In this thesis we investigate possible connections between cosmological inflation and leptogenesis on the one side and particle physics on the other side. We work in supersymmetric extensions of the Standard Model. A key role is played by the right-handed sneutrino, the superpartner of the right-handed neutrino involved in the type I seesaw mechanism. We study a combined model of inflation and non-thermal leptogenesis that is a simple extension of the Minimal Supersymmetric Standard Model (MSSM) with conserved R-parity, where we add three right-handed neutrino super fields. The inflaton direction is given by the imaginary components of the corresponding scalar component fields, which are protected from the supergravity (SUGRA) η-problem by a shift symmetry in the Kaehler potential. We discuss the model first in a globally supersymmetric (SUSY) and then in a supergravity context and compute the inflationary predictions of the model. We also study reheating and non-thermal leptogenesis in this model. A numerical simulation shows that shortly after the waterfall phase transition that ends inflation, the universe is dominated by right-handed sneutrinos and their out-of-equilibrium decay can produce the desired matter-antimatter asymmetry. Using a simplified time-averaged description, we derive analytical expressions for the model predictions. Combining the results from inflation and leptogenesis allows us to constrain the allowed parameter space from two different directions, with implications for low energy neutrino physics. As a second thread of investigation, we discuss a generalisation of the inflationary model discussed above to include gauge non-singlet fields as inflatons. This is motivated by the fact that in left-right symmetric, supersymmetric Grand Unified Theories (SUSY GUTs), like SUSY Pati-Salam unification or SUSY SO(10) GUTs, the righthanded (s)neutrino is an indispensable ingredient and does not have to be put in by hand as in the MSSM. We discuss the

Early universe cosmology. In supersymmetric extensions of the standard model

Energy Technology Data Exchange (ETDEWEB)

Baumann, Jochen Peter

2012-03-19

In this thesis we investigate possible connections between cosmological inflation and leptogenesis on the one side and particle physics on the other side. We work in supersymmetric extensions of the Standard Model. A key role is played by the right-handed sneutrino, the superpartner of the right-handed neutrino involved in the type I seesaw mechanism. We study a combined model of inflation and non-thermal leptogenesis that is a simple extension of the Minimal Supersymmetric Standard Model (MSSM) with conserved R-parity, where we add three right-handed neutrino super fields. The inflaton direction is given by the imaginary components of the corresponding scalar component fields, which are protected from the supergravity (SUGRA) {eta}-problem by a shift symmetry in the Kaehler potential. We discuss the model first in a globally supersymmetric (SUSY) and then in a supergravity context and compute the inflationary predictions of the model. We also study reheating and non-thermal leptogenesis in this model. A numerical simulation shows that shortly after the waterfall phase transition that ends inflation, the universe is dominated by right-handed sneutrinos and their out-of-equilibrium decay can produce the desired matter-antimatter asymmetry. Using a simplified time-averaged description, we derive analytical expressions for the model predictions. Combining the results from inflation and leptogenesis allows us to constrain the allowed parameter space from two different directions, with implications for low energy neutrino physics. As a second thread of investigation, we discuss a generalisation of the inflationary model discussed above to include gauge non-singlet fields as inflatons. This is motivated by the fact that in left-right symmetric, supersymmetric Grand Unified Theories (SUSY GUTs), like SUSY Pati-Salam unification or SUSY SO(10) GUTs, the righthanded (s)neutrino is an indispensable ingredient and does not have to be put in by hand as in the MSSM. We discuss

Results from GRACE/SUSY at one-loop

International Nuclear Information System (INIS)

Fujimoto, J.; Ishikawa, T.; Kurihara, Y.; Jimbo, M.; Yasui, Y.; Kaneko, T.; Kon, T.; Kuroda, M.; Shimizu, Y.

2007-01-01

We report the recent development on the SUSY calculations with the help of GRACE system. GRACE/SUSY/1LOOP is the computer code which can generate Feynman diagrams in the MSSM automatically and compute one-loop amplitudes in the numerical way. We present new results of various two-body widths and chargino pair production at ILC (international linear collider) at one-loop level. (author)

The pMSSM10 after LHC Run 1

International Nuclear Information System (INIS)

De Vries, K.J.; Buchmueller, O.

2015-04-01

We present a frequentist analysis of the parameter space of the pMSSM10, in which the following 10 soft SUSY-breaking parameters are specified independently at the mean scalar top mass scale M SUSY ≡√(m t 1 m t 2 ): the gaugino masses M 1,2,3 , the 1st-and 2nd-generation squark masses m q 1 =m q 2 , the third-generation squark mass m q 3 , a common slepton mass M l and a common trilinear mixing parameter A, the Higgs mixing parameter μ, the pseudoscalar Higgs mass M A and tan β. We use the MultiNest sampling algorithm with ∝1.2 x 10 9 points to sample the pMSSM10 parameter space. A dedicated study shows that the sensitivities to strongly-interacting SUSY masses of ATLAS and CMS searches for jets, leptons+E T signals depend only weakly on many of the other pMSSM10 parameters. With the aid of the Atom and Scorpion codes, we also implement the LHC searches for EW-interacting sparticles and light stops, so as to confront the pMSSM10 parameter space with all relevant SUSY searches. In addition, our analysis includes Higgs mass and rate measurements using the HiggsSignals code, SUSY Higgs exclusion bounds, the measurements B-physics observables, EW precision observables, the CDM density and searches for spin-independent DM scattering. We show that the pMSSM10 is able to provide a SUSY interpretation of (g-2) μ , unlike the CMSSM, NUHM1 and NUHM2. As a result, we find (omitting Higgs rates) that the minimum χ 2 /d.o.f.=20.5/18 in the pMSSM10, corresponding to a χ 2 probability of 30.8 %, to be compared with χ 2 /d.o.f.=32.8/24(31.1/23)(30.3/22) in the CMSSM (NUHM1) (NUHM2). We display 1-dimensional likelihood functions for SUSY masses, and show that they may be significantly lighter in the pMSSM10 than in the CMSSM, NUHM1 and NUHM2. We discuss the discovery potential of future LHC runs, e + e - colliders and direct detection experiments.

SUSY searches with the ATLAS detector

CERN Document Server

Ventura, Andrea; The ATLAS collaboration

2016-01-01

Despite the absence of experimental evidence, weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. This talk summarises recent ATLAS results for searches for supersymmetric (SUSY) particles, with focus on those obtained using proton-proton collisions at a centre of mass energy of 13 TeV. Strong production in both R-Parity conserving and R-Parity violating SUSY scenarios are considered. The searches involved final states including jets, missing transverse momentum, light leptons, as well as long-lived particle signatures.

Proton decay in the super-world

International Nuclear Information System (INIS)

Raby, S.

1986-01-01

Predictions are elaborated for nucleon decay in supersymmetric grand unified theories (SUSY GUT's). A minimal SU 5 SUSY GUT is described, as well as SU 5 breaking. The low energy theory and breaking of supersymmetry are discussed. It is concluded that nucleon decay in SUSY GUT's would be dominated by p → K + anti nu/sub μ/ and n → K 0 anti nu/sub μ/. There are ranges in parameter space for which other decay modes may be significant or may even dominate, it is found. It is noted that minimal SUSY GUT's typically predict a value of sin 2 θ/sub w/ of order .233. 20 refs., 7 figs

High scale parity invariance as a solution to the SUSY CP problem ...

Indian Academy of Sciences (India)

scale SUSY ДК model provides a solution to the CP problems of the MSSM. A minimal version of this .... the renormalizable seesaw model so that К-parity conservation remains automatic. Pramana – J. Phys., Vol ... from the Planck scale to ЪК in the squark sector is to split the third generation squarks slightly from the first two ...

Flavour symmetries and SUSY soft breaking in the LHC era

International Nuclear Information System (INIS)

Vives, O

2008-01-01

The so-called supersymmetric flavour problem does not exist in isolation to the Standard Model flavour problem. We show that a realistic flavour symmetry can simultaneously solve both problems without ad hoc modifications of the SUSY model. Furthermore, departures from the SM expectations in these models can be used to discriminate among different possibilities. In particular we present the expected values for the electron EDM in a flavour model solving the supersymmetric flavour and CP problems

The pMSSM10 after LHC Run 1

CERN Document Server

de Vries, K.J.; Buchmueller, O.; Cavanaugh, R.; Citron, M.; De Roeck, A.; Dolan, M.J.; Ellis, J.R.; Flächer, H.; Heinemeyer, S.; Isidori, G.; Malik, S.; Marrouche, J.; Martinez Santos, D.; Olive, K.A.; Sakurai, K.; Weiglein, G.

2015-01-01

We present a frequentist analysis of the parameter space of the pMSSM10, in which the following 10 soft SUSY-breaking parameters are specified independently at the mean scalar top mass scale Msusy = Sqrt[M_stop1 M_stop2]: the gaugino masses M_{1,2,3}, the 1st-and 2nd-generation squark masses M_squ1 = M_squ2, the third-generation squark mass M_squ3, a common slepton mass M_slep and a common trilinear mixing parameter A, the Higgs mixing parameter mu, the pseudoscalar Higgs mass M_A and tan beta. We use the MultiNest sampling algorithm with 1.2 x 10^9 points to sample the pMSSM10 parameter space. A dedicated study shows that the sensitivities to strongly-interacting SUSY masses of ATLAS and CMS searches for jets, leptons + MET signals depend only weakly on many of the other pMSSM10 parameters. With the aid of the Atom and Scorpion codes, we also implement the LHC searches for EW-interacting sparticles and light stops, so as to confront the pMSSM10 parameter space with all relevant SUSY searches. In addition, ou...

Noncommutative GUTs, Standard Model and C,P,T

International Nuclear Information System (INIS)

Aschieri, P.; Jurco, B.; Schupp, P.; Wess, J.

2003-01-01

Noncommutative Yang-Mills theories are sensitive to the choice of the representation that enters in the gauge kinetic term. We constrain this ambiguity by considering grand unified theories. We find that at first order in the noncommutativity parameter θ, SU(5) is not truly a unified theory, while SO(10) has a unique noncommutative generalization. In view of these results we discuss the noncommutative SM theory that is compatible with SO(10) GUT and find that there are no modifications to the SM gauge kinetic term at lowest order in θ. We study in detail the reality, Hermiticity and C,P,T properties of the Seiberg-Witten map and of the resulting effective actions expanded in ordinary fields. We find that in models of GUTs (or compatible with GUTs) right-handed fermions and left-handed ones appear with opposite Seiberg-Witten map

Noncommutative GUTs, Standard Model and C,P,T

Energy Technology Data Exchange (ETDEWEB)

Aschieri, P. E-mail: aschieri@theorie.physik.uni-muenchen.de; Jurco, B. E-mail: jurco@theorie.physik.uni-muenchen.de; Schupp, P. E-mail: p.schupp@iu-bremen.de; Wess, J. E-mail: wess@theorie.physik.uni-muenchen.de

2003-02-17

Noncommutative Yang-Mills theories are sensitive to the choice of the representation that enters in the gauge kinetic term. We constrain this ambiguity by considering grand unified theories. We find that at first order in the noncommutativity parameter {theta}, SU(5) is not truly a unified theory, while SO(10) has a unique noncommutative generalization. In view of these results we discuss the noncommutative SM theory that is compatible with SO(10) GUT and find that there are no modifications to the SM gauge kinetic term at lowest order in {theta}. We study in detail the reality, Hermiticity and C,P,T properties of the Seiberg-Witten map and of the resulting effective actions expanded in ordinary fields. We find that in models of GUTs (or compatible with GUTs) right-handed fermions and left-handed ones appear with opposite Seiberg-Witten map.

Electric dipole moments from spontaneous CP violation in SU(3)-flavoured SUSY

International Nuclear Information System (INIS)

Jones Perez, J

2009-01-01

The SUSY flavour problem is deeply related to the origin of flavour and hence to the origin of the SM Yukawa couplings themselves. Since all CP-violation in the SM is restricted to the flavour sector, it is possible that the SUSY CP problem is related to the origin of flavour as well. In this work, we present three variations of an SU(3) flavour model with spontaneous CP violation. Such models explain the hierarchy in the fermion masses and mixings, and predict the structure of the flavoured soft SUSY breaking terms. In such a situation, both SUSY flavour and CP problems do not exist. We use electric dipole moments and lepton flavour violation processes to distinguish between these models, and place constraints on the SUSY parameter space.

The hyperbolic step potential: Anti-bound states, SUSY partners and Wigner time delays

Energy Technology Data Exchange (ETDEWEB)

Gadella, M. [Departamento de Física Teórica, Atómica y Óptica and IMUVA, Universidad de Valladolid, E-47011 Valladolid (Spain); Kuru, Ş. [Department of Physics, Faculty of Science, Ankara University, 06100 Ankara (Turkey); Negro, J., E-mail: jnegro@fta.uva.es [Departamento de Física Teórica, Atómica y Óptica and IMUVA, Universidad de Valladolid, E-47011 Valladolid (Spain)

2017-04-15

We study the scattering produced by a one dimensional hyperbolic step potential, which is exactly solvable and shows an unusual interest because of its asymmetric character. The analytic continuation of the scattering matrix in the momentum representation has a branch cut and an infinite number of simple poles on the negative imaginary axis which are related with the so called anti-bound states. This model does not show resonances. Using the wave functions of the anti-bound states, we obtain supersymmetric (SUSY) partners which are the series of Rosen–Morse II potentials. We have computed the Wigner reflection and transmission time delays for the hyperbolic step and such SUSY partners. Our results show that the more bound states a partner Hamiltonian has the smaller is the time delay. We also have evaluated time delays for the hyperbolic step potential in the classical case and have obtained striking similitudes with the quantum case. - Highlights: • The scattering matrix of hyperbolic step potential is studied. • The scattering matrix has a branch cut and an infinite number of poles. • The poles are associated to anti-bound states. • Susy partners using antibound states are computed. • Wigner time delays for the hyperbolic step and partner potentials are compared.

SUSY Search at LHC

CERN Document Server

Xu, Da; The ATLAS collaboration

2018-01-01

Despite the absence of experimental evidence, weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. This talk gives an overview of the most recent SUSY searches in ATLAS and CMS experiments using 13 TeV ATLAS Run2 data.

SUSY/non-SUSY duality in U(N gauge model with partially broken N=2 supersymmetry

Directory of Open Access Journals (Sweden)

Kazunobu Maruyoshi

2009-03-01

Full Text Available We study the vacuum structure of the U(N gauge model with partially broken N=2 supersymmetry. From the analysis of the classical vacua of this model, we point out that in addition to the ordinary N=1 supersymmetric vacua, there are vacua with negative gauge coupling constants, which preserve another N=1 supersymmetry. These latter vacua can be analyzed by using SUSY/non-SUSY duality which is recently proposed by Aganagic, Beem, Seo and Vafa. A dual description of these in UV is U(N gauge theory where the supersymmetry is broken by spurion superfields. Following them, we see that there are supersymmetry preserving vacua as well as supersymmetry breaking vacua of low energy effective theory.

Supersymmetry searches in GUT models with non-universal scalar masses

Energy Technology Data Exchange (ETDEWEB)

Cannoni, M.; Gómez, M.E. [Departamento de Física Aplicada, Facultad de Ciencias Experimentales, Universidad de Huelva, 21071 Huelva (Spain); Ellis, J. [Theoretical Particle Physics and Cosmology Group, Physics Department, King' s College London, London WC2R 2LS (United Kingdom); Lola, S. [Department of Physics, University of Patras, 26500 Patras (Greece); De Austri, R. Ruiz, E-mail: mirco.cannoni@dfa.uhu.es, E-mail: John.Ellis@cern.ch, E-mail: mario.gomez@dfa.uhu.es, E-mail: magda@physics.upatras.gr, E-mail: rruiz@ific.uv.es [Instituto de Física Corpuscular, IFIC-UV/CSIC, Valencia (Spain)

2016-03-01

We study SO(10), SU(5) and flipped SU(5) GUT models with non-universal soft supersymmetry-breaking scalar masses, exploring how they are constrained by LHC supersymmetry searches and cold dark matter experiments, and how they can be probed and distinguished in future experiments. We find characteristic differences between the various GUT scenarios, particularly in the coannihilation region, which is very sensitive to changes of parameters. For example, the flipped SU(5) GUT predicts the possibility of ∼t{sub 1}−χ coannihilation, which is absent in the regions of the SO(10) and SU(5) GUT parameter spaces that we study. We use the relic density predictions in different models to determine upper bounds for the neutralino masses, and we find large differences between different GUT models in the sparticle spectra for the same LSP mass, leading to direct connections of distinctive possible experimental measurements with the structure of the GUT group. We find that future LHC searches for generic missing E{sub T}, charginos and stops will be able to constrain the different GUT models in complementary ways, as will the Xenon 1 ton and Darwin dark matter scattering experiments and future FERMI or CTA γ-ray searches.

We still love SUSY

Energy Technology Data Exchange (ETDEWEB)

Anon.

1992-11-15

Supersymmetry, affectionately known as SUSY, is still the darling of theoretical particle physics. Invented some 20 years ago, the charismatic idea really took off at the beginning of the 1980s. At the time, a workshop at CERN reflected the youthful enthusiasm for these new ideas.

We still love SUSY

International Nuclear Information System (INIS)

Anon.

1992-01-01

Supersymmetry, affectionately known as SUSY, is still the darling of theoretical particle physics. Invented some 20 years ago, the charismatic idea really took off at the beginning of the 1980s. At the time, a workshop at CERN reflected the youthful enthusiasm for these new ideas

Hydrogen-antihydrogen oscillations: Signature of intermediate mass scales in GUTs

Directory of Open Access Journals (Sweden)

Uptal Sarkar

1983-01-01

Full Text Available Hydrogen-antihydrogen oscillations and the double nucleon decay (pp, np and nn into two antileptons are discussed in the context of SO(10, E(6 and SU(16 GUTs. It is shown that the intermediate mass scales of the GUTs concerned govern the amplitude of these processes which are found to compete with the other baryon nonconserving processes in SU(16 GUT.

Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

Index Scriptorium Estoniae

Maimets, Andri, 1979-

2003-01-01

Concordia Ülikooli rektor Mart Susi esitas kohtule avalduse, milles taotleb ülikooli pidanud Concordia Varahalduse OÜ pankroti väljakuulutamist. Vt. samas: Mari-Ann Susi õigustas ülikooli raha kasutamist

Non-linear way to supersymmetry and N-extended SUSY

International Nuclear Information System (INIS)

Akulov, V.

2001-01-01

In this report I give a short historical review of some of the first steps that were done towards the invention of SUSY by the Kharkov team headed by D. Volkov. This article is dedicated to the memory of Prof. Yuri Golfand, whose ideas of SUSY inspired the most active developments in High Energy Physics over thirty years

Analytical Solution of Dirac Equation for q-Deformed Hyperbolic Manning-Rosen Potential in D Dimensions using SUSY QM and its Thermodynamics Application

International Nuclear Information System (INIS)

Cari, C; Suparmi, A; Yunianto, M; Pratiwi, B N

2016-01-01

The Dirac equation of q-deformed hyperbolic Manning Rosen potential in D dimension was solved by using Supersymmetric Quantum Mechanics (SUSY QM). The D dimensional relativistic energy spectra were obtained by using SUSY QM and shape invariant properties and D dimensional wave functions of q-deformed hyperbolic Manning Rosen potential were obtained by using the SUSY raising and lowering operators. In the nonrelativistic limit, the relativistic energy spectra for exact spin symmetry case reduced into nonrelativistic energy spectra and so for the wave functions. In the classical regime, the partition function, the vibrational specific heat, and the vibrational mean energy of some diatomic molecules were calculated from the non-relativistic energy spectra with the help of error function and imaginary error function. (paper)

Post LHC8 SUSY benchmark points for ILC physics

International Nuclear Information System (INIS)

Baer, Howard; List, Jenny

2013-07-01

We re-evaluate prospects for supersymmetry at the proposed International Linear e + e - Collider (ILC) in light of the first two years of serious data taking at LHC: LHC7 with ∝5 fb -1 of pp collisions at √(s)=7 TeV and LHC8 with ∝20 fb -1 at √(s)=8 TeV. Strong new limits from LHC8 SUSY searches, along with the discovery of a Higgs boson with m h ≅125 GeV, suggest a paradigm shift from previously popular models to ones with new and compelling signatures. After a review of the current status of supersymmetry, we present a variety of new ILC benchmark models, including: natural SUSY, radiatively-driven natural SUSY (RNS), NUHM2 with low m A , a focus point case from mSUGRA/CMSSM, non-universal gaugino mass (NUGM) model, τ-coannihilation, Kallosh-Linde/spread SUSY model, mixed gauge-gravity mediation, normal scalar mass hierarchy (NMH), and one example with the recently discovered Higgs boson being the heavy CP-even state H. While all these models at present elude the latest LHC8 limits, they do offer intriguing case study possibilities for ILC operating at √(s)≅ 0.25-1 TeV. The benchmark points also present a view of the widely diverse SUSY phenomena which might still be expected in the post LHC8 era at both LHC and ILC.

Post LHC8 SUSY benchmark points for ILC physics

Energy Technology Data Exchange (ETDEWEB)

Baer, Howard [Oklahoma Univ., Norman, OK (United States); List, Jenny [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

2013-07-15

We re-evaluate prospects for supersymmetry at the proposed International Linear e{sup +}e{sup -} Collider (ILC) in light of the first two years of serious data taking at LHC: LHC7 with {proportional_to}5 fb{sup -1} of pp collisions at {radical}(s)=7 TeV and LHC8 with {proportional_to}20 fb{sup -1} at {radical}(s)=8 TeV. Strong new limits from LHC8 SUSY searches, along with the discovery of a Higgs boson with m{sub h}{approx_equal}125 GeV, suggest a paradigm shift from previously popular models to ones with new and compelling signatures. After a review of the current status of supersymmetry, we present a variety of new ILC benchmark models, including: natural SUSY, radiatively-driven natural SUSY (RNS), NUHM2 with low m{sub A}, a focus point case from mSUGRA/CMSSM, non-universal gaugino mass (NUGM) model, {tau}-coannihilation, Kallosh-Linde/spread SUSY model, mixed gauge-gravity mediation, normal scalar mass hierarchy (NMH), and one example with the recently discovered Higgs boson being the heavy CP-even state H. While all these models at present elude the latest LHC8 limits, they do offer intriguing case study possibilities for ILC operating at {radical}(s){approx_equal} 0.25-1 TeV. The benchmark points also present a view of the widely diverse SUSY phenomena which might still be expected in the post LHC8 era at both LHC and ILC.

SUSY long-lived massive particles. Detection and physics at the LHC

International Nuclear Information System (INIS)

Ambrosiano, S.; Mele, B.; Nisati, A.; Petrarca, S.; Polesello, G.; Rimoldi, A.; Salvini, G.

2001-01-01

It was drawn a possible scenario for the observation of massive long-lived charged particles at the LHC detector ATLAS. The required flexibility of the detector triggers and of the identification and reconstruction systems are discussed. As an example, it was focused on the measurement of the mass and lifetime of long-lived charged sleptons predicted in the framework of supersymmetric models with gauge-mediated supersymmetry (SUSY) breaking. In this case the next-to-lightest SUSY particle can be the light scalar partner of the tau lepton (τ 1 ), possibly decaying slowly into a gravitino. A wide region of the SUSY parameters space was explored. The accessible range and precision on the measurement of the SUSY breaking scale parameter of √ F achievable with a counting method are assessed [it

Latest news on SUSY from the ATLAS experiment

CERN Multimedia

CERN. Geneva

2016-01-01

Despite the absence of experimental evidence, weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. This talk reports the latest ATLAS results for searches for supersymmetric (SUSY) particles, obtained with 13 to 18 fb-1 of 13 TeV data. Weak and strong production in both R-Parity conserving and R-Parity violating SUSY scenarios are considered. The searches involved final states including jets, missing transverse momentum, light leptons, taus or photons.

Post LHC7 SUSY benchmark points for ILC physics

Energy Technology Data Exchange (ETDEWEB)

Baer, Howard [Oklahoma Univ., Norman, OK (United States); List, Jenny [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

2012-05-15

We re-evaluate prospects for supersymmetry at the proposed International Linear e{sup +}e{sup -} Collider (ILC) in light of the first year of serious data taking at LHC with {radical}(s)=7 TeV and {proportional_to}5 fb{sup -1} of pp collisions (LHC7). Strong new limits from LHC SUSY searches, along with a hint of a Higgs boson signal around m{sub h}{proportional_to}125 GeV, suggest a paradigm shift from previously popular models to ones with new and compelling signatures. We present a variety of new ILC benchmark models, including: natural SUSY, hidden SUSY, NUHM2 with low m{sub A}, non-universal gaugino mass (NUGM) model, pMSSM, Kallosh-Linde model, Bruemmer-Buchmueller model, normal scalar mass hierarchy (NMH) plus one surviving case from mSUGRA/CMSSM in the far focus point region. While all these models at present elude the latest LHC limits, they do offer intriguing case study possibilities for ILC operating at {radical}(s){proportional_to}0.25-1 TeV, and present a view of some of the diverse SUSY phenomena which might be expected at both LHC and ILC in the post LHC7 era.

Post LHC7 SUSY benchmark points for ILC physics

International Nuclear Information System (INIS)

Baer, Howard; List, Jenny

2012-05-01

We re-evaluate prospects for supersymmetry at the proposed International Linear e + e - Collider (ILC) in light of the first year of serious data taking at LHC with √(s)=7 TeV and ∝5 fb -1 of pp collisions (LHC7). Strong new limits from LHC SUSY searches, along with a hint of a Higgs boson signal around m h ∝125 GeV, suggest a paradigm shift from previously popular models to ones with new and compelling signatures. We present a variety of new ILC benchmark models, including: natural SUSY, hidden SUSY, NUHM2 with low m A , non-universal gaugino mass (NUGM) model, pMSSM, Kallosh-Linde model, Bruemmer-Buchmueller model, normal scalar mass hierarchy (NMH) plus one surviving case from mSUGRA/CMSSM in the far focus point region. While all these models at present elude the latest LHC limits, they do offer intriguing case study possibilities for ILC operating at √(s)∝0.25-1 TeV, and present a view of some of the diverse SUSY phenomena which might be expected at both LHC and ILC in the post LHC7 era.

METing SUSY on the Z peak

Energy Technology Data Exchange (ETDEWEB)

Barenboim, G.; Bernabeu, J.; Vives, O. [Universitat de Valencia, Departament de Fisica Teorica, Burjassot (Spain); Universitat de Valencia-CSIC, Parc Cientific U.V., IFIC, Paterna (Spain); Mitsou, V.A.; Romero, E. [Universitat de Valencia-CSIC, Parc Cientific U.V., IFIC, Paterna (Spain)

2016-02-15

Recently the ATLAS experiment announced a 3 σ excess at the Z-peak consisting of 29 pairs of leptons together with two or more jets, E{sub T}{sup miss} > 225 GeV and HT > 600 GeV, to be compared with 10.6 ± 3.2 expected lepton pairs in the Standard Model. No excess outside the Z-peak was observed. By trying to explain this signal with SUSY we find that only relatively light gluinos, m{sub g} or similar 400 GeV decaying predominantly to Z-boson plus a light gravitino, such that nearly every gluino produces at least one Z-boson in its decay chain, could reproduce the excess. We construct an explicit general gauge mediation model able to reproduce the observed signal overcoming all the experimental limits. Needless to say, more sophisticated models could also reproduce the signal, however, any model would have to exhibit the following features: light gluinos, or heavy particles with a strong production cross section, producing at least one Z-boson in its decay chain. The implications of our findings for the Run II at LHC with the scaling on the Z peak, as well as for the direct search of gluinos and other SUSY particles, are pointed out. (orig.)

METing SUSY on the Z peak

International Nuclear Information System (INIS)

Barenboim, G.; Bernabeu, J.; Vives, O.; Mitsou, V.A.; Romero, E.

2016-01-01

Recently the ATLAS experiment announced a 3 σ excess at the Z-peak consisting of 29 pairs of leptons together with two or more jets, E T miss > 225 GeV and HT > 600 GeV, to be compared with 10.6 ± 3.2 expected lepton pairs in the Standard Model. No excess outside the Z-peak was observed. By trying to explain this signal with SUSY we find that only relatively light gluinos, m g or similar 400 GeV decaying predominantly to Z-boson plus a light gravitino, such that nearly every gluino produces at least one Z-boson in its decay chain, could reproduce the excess. We construct an explicit general gauge mediation model able to reproduce the observed signal overcoming all the experimental limits. Needless to say, more sophisticated models could also reproduce the signal, however, any model would have to exhibit the following features: light gluinos, or heavy particles with a strong production cross section, producing at least one Z-boson in its decay chain. The implications of our findings for the Run II at LHC with the scaling on the Z peak, as well as for the direct search of gluinos and other SUSY particles, are pointed out. (orig.)

Possible constraints on SUSY-model parameters from direct dark matter search

International Nuclear Information System (INIS)

Bednyakov, V.A.; Kovalenko, S.G.

1993-01-01

We consider the SUSY-model neutralino as a dominant Dark Matter particle in the galactic halo and investigate some general issues of direct DM searches via elastic neutralino-nucleus scattering. On the basis of conventional assumptions about the nuclear and nucleon structure, without referring to a specific SUSY-model, we prove that it is impossible in principle to extract more than three constrains on fundamental SUSY-model parameters from the direct Dark Matter searches. Three types of Dark Matter detector probing different groups of parameters are recognized. 21 refs., 1 tab

Non-universal SUSY breaking, hierarchy and squark degeneracty

International Nuclear Information System (INIS)

Murayama, Hitoshi.

1995-01-01

I discuss non-trivial effects in the soft SUSY breaking terms which appear when one integrates out heavy fields. The effects exist only when the SUSY breaking terms are non-universal. They may spoil (1) the hierarchy between the weak and high-energy scales, or (2) degeneracy among the squark masses even in the presense of a horizontal symmetry. I argue, in the end, that such new effects may be useful in probing physics at high-energy scales from TeV-scale experiments

The supersymmetric flavour problem in 5D GUTs and its consequences for LHC phenomenology

International Nuclear Information System (INIS)

Bruemmer, F.; Fichet, S.; Kraml, S.

2011-09-01

We study supersymmetric models with a GUT-sized extra dimension, where both the Higgs fields and the SUSY breaking hidden sector are localized on a 4D brane. Exponential wave function profiles of the matter fields give rise to hierarchical structures in the Yukawa couplings and soft terms. Such structures can naturally explain hierarchical fermion masses and mixings, while at the same time alleviating the supersymmetric flavour problem. We discuss two sources of supersymmetry breaking, radion mediation and brane fields, and perform a detailed numerical analysis, thoroughly taking into account the proliferation of unknown O(1) coefficients that occurs in this class of models. It turns out that additional assumptions on supersymmetry breaking are necessary to evade the stringent experimental bounds on lepton flavour violation. The favourable regions of parameter space are then examined with regards to their LHC phenomenology. They generically feature heavy gluinos and squarks beyond current bounds. Lepton flavour violation in SUSY cascade decays can give interesting signatures. (orig.)

The supersymmetric flavour problem in 5D GUTs and its consequences for LHC phenomenology

Energy Technology Data Exchange (ETDEWEB)

Bruemmer, F. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Fichet, S.; Kraml, S. [CNRS/IN2P3, Grenoble (France). Lab. de Physique Subatomique et de Cosmologie

2011-09-15

We study supersymmetric models with a GUT-sized extra dimension, where both the Higgs fields and the SUSY breaking hidden sector are localized on a 4D brane. Exponential wave function profiles of the matter fields give rise to hierarchical structures in the Yukawa couplings and soft terms. Such structures can naturally explain hierarchical fermion masses and mixings, while at the same time alleviating the supersymmetric flavour problem. We discuss two sources of supersymmetry breaking, radion mediation and brane fields, and perform a detailed numerical analysis, thoroughly taking into account the proliferation of unknown O(1) coefficients that occurs in this class of models. It turns out that additional assumptions on supersymmetry breaking are necessary to evade the stringent experimental bounds on lepton flavour violation. The favourable regions of parameter space are then examined with regards to their LHC phenomenology. They generically feature heavy gluinos and squarks beyond current bounds. Lepton flavour violation in SUSY cascade decays can give interesting signatures. (orig.)

Naturalness in low-scale SUSY models and "non-linear" MSSM

CERN Document Server

Antoniadis, I; Ghilencea, D M

2014-01-01

In MSSM models with various boundary conditions for the soft breaking terms (m_{soft}) and for a higgs mass of 126 GeV, there is a (minimal) electroweak fine-tuning Delta\\approx 800 to 1000 for the constrained MSSM and Delta\\approx 500 for non-universal gaugino masses. These values, often regarded as unacceptably large, may indicate a problem of supersymmetry (SUSY) breaking, rather than of SUSY itself. A minimal modification of these models is to lower the SUSY breaking scale in the hidden sector (\\sqrt f) to few TeV, which we show to restore naturalness to more acceptable levels Delta\\approx 80 for the most conservative case of low tan_beta and ultraviolet boundary conditions as in the constrained MSSM. This is done without introducing additional fields in the visible sector, unlike other models that attempt to reduce Delta. In the present case Delta is reduced due to additional (effective) quartic higgs couplings proportional to the ratio m_{soft}/(\\sqrt f) of the visible to the hidden sector SUSY breaking...

Sneutrino driven GUT inflation in supergravity

International Nuclear Information System (INIS)

Gonzalo, Tomás E.; Heurtier, Lucien; Moursy, Ahmad

2017-01-01

In this paper, we embed the model of flipped GUT sneutrino inflation — in a flipped SU(5) or SO(10) set up — developed by Ellis et al. in a supergravity framework. The GUT symmetry is broken by a waterfall which could happen at early or late stage of the inflationary period. The full field dynamics is thus studied in detail and these two main inflationary configurations are exposed, whose cosmological predictions are both in agreement with recent astrophysical measurements. The model has an interesting feature where the inflaton has natural decay channels to the MSSM particles allowed by the GUT gauge symmetry. Hence it can account for the reheating after the inflationary epoch.

Sneutrino driven GUT inflation in supergravity

Science.gov (United States)

Gonzalo, Tomás E.; Heurtier, Lucien; Moursy, Ahmad

2017-06-01

In this paper, we embed the model of flipped GUT sneutrino inflation — in a flipped SU(5) or SO(10) set up — developed by Ellis et al. in a supergravity framework. The GUT symmetry is broken by a waterfall which could happen at early or late stage of the inflationary period. The full field dynamics is thus studied in detail and these two main inflationary configurations are exposed, whose cosmological predictions are both in agreement with recent astrophysical measurements. The model has an interesting feature where the inflaton has natural decay channels to the MSSM particles allowed by the GUT gauge symmetry. Hence it can account for the reheating after the inflationary epoch.

A Bottom-Up Approach to SUSY Analyses

Energy Technology Data Exchange (ETDEWEB)

Horn, Claus; /SLAC

2011-11-11

This paper proposes a new way to do event generation and analysis in searches for new physics at the LHC. An abstract notation is used to describe the new particles on a level which better corresponds to detector resolution of LHC experiments. In this way the SUSY discovery space can be decomposed into a small number of eigenmodes each with only a few parameters, which allows to investigate the SUSY parameter space in a model-independent way. By focusing on the experimental observables for each process investigated the Bottom-Up Approach allows to systematically study the boarders of the experimental efficiencies and thus to extend the sensitivity for new physics.

Leptogenesis scenarios for natural SUSY with mixed axion-higgsino dark matter

International Nuclear Information System (INIS)

Bae, Kyu Jung; Baer, Howard; Serce, Hasan; Zhang, Yi-Fan

2016-01-01

Supersymmetric models with radiatively-driven electroweak naturalness require light higgsinos of mass ∼ 100–300 GeV . Naturalness in the QCD sector is invoked via the Peccei-Quinn (PQ) axion leading to mixed axion-higgsino dark matter. The SUSY DFSZ axion model provides a solution to the SUSY μ problem and the Little Hierarchy μ|| m 3/2 may emerge as a consequence of a mismatch between PQ and hidden sector mass scales. The traditional gravitino problem is now augmented by the axino and saxion problems, since these latter particles can also contribute to overproduction of WIMPs or dark radiation, or violation of BBN constraints. We compute regions of the T R vs. m 3/2 plane allowed by BBN, dark matter and dark radiation constraints for various PQ scale choices f a . These regions are compared to the values needed for thermal leptogenesis, non-thermal leptogenesis, oscillating sneutrino leptogenesis and Affleck-Dine leptogenesis. The latter three are allowed in wide regions of parameter space for PQ scale f a∼  10 10 –10 12 GeV which is also favored by naturalness: f a  ∼ √μM P /λ μ  ∼ 10 10 –10 12 GeV . These f a values correspond to axion masses somewhat above the projected ADMX search regions

Neutrino oscillations in a predictive SUSY GUT

International Nuclear Information System (INIS)

Blazek, T.; Raby, S.; Tobe, K.

1999-01-01

In this paper we present a predictive SO(10) supersymmetric grand unified theory with the family symmetry U(2)xU(1) which has several nice features. We are able to fit fermion masses and mixing angles, including recent neutrino data, with nine parameters in the charged fermion sector and four in the neutrino sector. The family symmetry plays a preeminent role. (i) The model is ''natural''--we include all terms allowed by the symmetry. It restricts the number of arbitrary parameters and enforces many zeros in the effective mass matrices. (ii) Family symmetry breaking from U(2)xU(1)→U(1)→ nothing generates the family hierarchy. It also constrains squark and slepton mass matrices, thus ameliorating flavor violation resulting from squark and slepton loop contributions. (iii) It naturally gives large angle ν μ -ν τ mixing describing atmospheric neutrino oscillation data and small angle ν e -ν s mixing, consistent with the small mixing angle Mikheyev-Smirnov-Wolfenstein (MSW) solution to solar neutrino data. (iv) Finally, in this paper we assume minimal family symmetry-breaking vacuum expectation values (VEV's). As a result we cannot obtain a three neutrino solution to both atmospheric and solar neutrino oscillations. In addition, the solution discussed here cannot fit liquid scintillation neutrino detector (LSND) data even though this solution requires a sterile neutrino ν s . It is important to note, however, that with nonminimal family symmetry-breaking VEV's, a three neutrino solution is possible with the small mixing angle MSW solution to solar neutrino data and large angle ν μ -ν τ mixing describing atmospheric neutrino oscillation data. In the four neutrino case, nonminimal family VEV's may also permit a solution for LSND. The results with nonminimal family breaking are still under investigation and will be reported in a future paper. (c) 1999 The American Physical Society

GUTs, SUSY GUTs and SUPER GUTs

International Nuclear Information System (INIS)

Gaillard, M.K.

1982-07-01

We review the motivations for extending grand unified theories with particular emphasis on supersymmetry and its phenomenological and cosmological fallout, and comment on the relevance of quantum gravity. 67 references

Supersymmetric SO(10) models inspired by deconstruction

International Nuclear Information System (INIS)

Huang Chaoshang; Jiang Jing; Li Tianjun

2004-01-01

We consider 4-dimensional N=1 supersymmetric SO(10) models inspired by deconstruction of 5-dimensional N=1 supersymmetric orbifold SO(10) models and high-dimensional non-supersymmetric SO(10) models with Wilson line gauge symmetry breaking. We discuss the SO(10)xSO(10) models with bi-fundamental link fields where the gauge symmetry can be broken down to the Pati-Salam, SU(5)xU(1), flipped SU(5)xU(1)' or the Standard Model like gauge symmetry. We also propose an SO(10)xSO(6)xSO(4) model with bi-fundamental link fields where the gauge symmetry is broken down to the Pati-Salam gauge symmetry, and an SO(10)xSO(10) model with bi-spinor link fields where the gauge symmetry is broken down to the flipped SU(5)xU(1)' gauge symmetry. In these two models, the Pati-Salam and flipped SU(5)xU(1)' gauge symmetry can be further broken down to the Standard Model gauge symmetry, the doublet-triplet splittings can be obtained by the missing partner mechanism, and the proton decay problem can be solved. We also study the gauge coupling unification. We briefly comment on the interesting variation models with gauge groups SO(10)xSO(6) and SO(10)xflippedSU(5)xU(1)' in which the proton decay problem can be solved

Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

Index Scriptorium Estoniae

Maimets, Andri

2003-01-01

Concordia Ülikooli rektori kohast loobunud Mart Susi ning prorektori ametikohalt lahkunud Mari-Ann Susi taotlevad neile kuuluvat ülikooli pidanud miljonivõlgades firma pankrotti. Hiljuti loodi õppejõududest, tudengitest js töötajatest mittetulundusühing Concordia Akadeemiline Ühisus (CAU), selle nõukogu esimees on Hagi Šein

Neutrino oscillations from discrete non-Abelian family symmetries

International Nuclear Information System (INIS)

Schmaltz, M.

1995-01-01

I disuss a SUSY GUT model with a non-Abelian discrete family symmetry that explains the observed hierarchical pattern of quark and lepton masses. This SO(10)xΔ(75) model predicts modified quadratic seesaw neutrino masses and mixing angles which are interesting for three reasons: (i) they offer a solution to the solar neutrino problem, (ii) the τ neutrino has the right mass for a cosmologically interesting hot dark matter candidate, and (iii) they suggest a positive result for the ν μ →ν τ oscillation searches by the CHORUS and NOMAD Collaborations. However, the model shares some problems with many other predictive GUT models of quark and lepton masses. The predictions from well-known mass and angle relations, such as the relation λ b GUT =λ τ GUT , fail in many cases. Attempts to correct these relations seem to lead to rather contrived models

Coupling between scattering channels with SUSY transformations for equal thresholds

International Nuclear Information System (INIS)

Pupasov, Andrey M; Samsonov, Boris F; Sparenberg, Jean-Marc; Baye, Daniel

2009-01-01

Supersymmetric (SUSY) transformations of the multichannel Schroedinger equation with equal thresholds and arbitrary partial waves in all channels are studied. The structures of the transformation function and the superpotential are analysed. Relations between Jost and scattering matrices of superpartner potentials are obtained. In particular, we show that a special type of SUSY transformation allows us to introduce a coupling between scattering channels starting from a potential with an uncoupled scattering matrix. The possibility for this coupling to be trivial is discussed. We show that the transformation introduces bound and virtual states with a definite degeneracy at the factorization energy. A detailed study of the potential and scattering matrices is given for the 2 x 2 case. The possibility of inverting coupled-channel scattering data by such a SUSY transformation is demonstrated by several examples (s-s, s-p and s-d partial waves)

Towards the natural gauge mediation

Energy Technology Data Exchange (ETDEWEB)

Ding, Ran [Center for High-Energy Physics, Peking University,Beijing, 100871 (China); Li, Tianjun [State Key Laboratory of Theoretical Physics andKavli Institute for Theoretical Physics, China (KITPC), Institute of Theoretical Physics,Chinese Academy of Sciences, Beijing 100190 (China); School of Physical Electronics, University of Electronic Science and Technology of China,Chengdu 610054 (China); Wang, Liucheng [Bartol Research Institute, Department of Physics and Astronomy,University of Delaware, Newark, DE 19716 (United States); Zhu, Bin [State Key Laboratory of Theoretical Physics andKavli Institute for Theoretical Physics, China (KITPC), Institute of Theoretical Physics,Chinese Academy of Sciences, Beijing 100190 (China); Institute of Physics Chinese Academy of sciences,Beijing 100190 (China)

2015-10-23

The sweet spot supersymmetry (SUSY) solves the μ/B{sub μ} problem in the Minimal Supersymmetric Standard Model (MSSM) with gauge mediated SUSY breaking (GMSB) via the generalized Giudice-Masiero (GM) mechanism where only the μ-term and soft Higgs masses are generated at the unification scale of the Grand Unified Theory (GUT) due to the approximate PQ symmetry. Because all the other SUSY breaking soft terms are generated via the GMSB below the GUT scale, there exists SUSY electroweak (EW) fine-tuning problem to explain the 125 GeV Higgs boson mass due to small trilinear soft term. Thus, to explain the Higgs boson mass, we propose the GMSB with both the generalized GM mechanism and Higgs-messenger interactions. The renormalization group equations are runnings from the GUT scale down to EW scale. So the EW symmetry breaking can be realized easier. We can keep the gauge coupling unification and solution to the flavor problem in the GMSB, as well as solve the μ/B{sub μ}-problem. Moreover, there are only five free parameters in our model. So we can determine the characteristic low energy spectra and explore its distinct phenomenology. The fine-tuning measure can be as low as 100. For some benchmark points, the stop mass can be as low as 1.7 TeV while the glunio mass is around 2.5 TeV. The gravitino dark matter can come from a thermal production with the correct relic density and be consistent with the thermal leptogenesis. Because gluino and stop can be relatively light in our model, how to search for such GMSB at the upcoming run II of the LHC experiment could be very interesting.

Split-Family SUSY, U(2)^5 Flavour Symmetry and Neutrino Physics

CERN Document Server

Jones-Pérez, Joel

2014-01-01

In split-family SUSY, one can use a U(2)^3 symmetry to protect flavour observables in the quark sector from SUSY contributions. However, attempts to extend this procedure to the lepton sector by using an analogous U(2)^5 symmetry fail to reproduce the neutrino data without introducing some form of fine-tuning. In this work, we solve this problem by shifting the U(2)^2 symmetry acting on leptons towards the second and third generations. This allows neutrino data to be reproduced without much difficulties, as well as protecting the leptonic flavour observables from SUSY. Key signatures are a $\\mu\\to e\\gamma$ branching ratio possibly observable in the near future, as well as having selectrons as the lightest sleptons.

SUSY WT identity in a lattice formulation of 2D N=(2,2) SYM

International Nuclear Information System (INIS)

Kadoh, Daisuke; Suzuki, Hiroshi

2010-01-01

We address some issues relating to a supersymmetric (SUSY) Ward-Takahashi (WT) identity in Sugino's lattice formulation of two-dimensional (2D) N=(2,2)SU(k) supersymmetric Yang-Mills theory (SYM). A perturbative argument shows that the SUSY WT identity in the continuum theory is reproduced in the continuum limit without any operator renormalization/mixing and tuning of lattice parameters. As application of the lattice SUSY WT identity, we show that a prescription for the Hamiltonian density in this lattice formulation, proposed by Kanamori, Sugino and Suzuki, is justified also from a perspective of an operator algebra among correctly-normalized supercurrents. We explicitly confirm the SUSY WT identity in the continuum limit to the first nontrivial order in a semi-perturbative expansion.

Decoupling limit and throat geometry of non-susy D3 brane

Energy Technology Data Exchange (ETDEWEB)

Nayek, Kuntal, E-mail: kuntal.nayek@saha.ac.in; Roy, Shibaji, E-mail: shibaji.roy@saha.ac.in

2017-03-10

Recently it has been shown by us that, like BPS Dp branes, bulk gravity gets decoupled from the brane even for the non-susy Dp branes of type II string theories indicating a possible extension of AdS/CFT correspondence for the non-supersymmetric case. In that work, the decoupling of gravity on the non-susy Dp branes has been shown numerically for the general case as well as analytically for some special case. Here we discuss the decoupling limit and the throat geometry of the non-susy D3 brane when the charge associated with the brane is very large. We show that in the decoupling limit the throat geometry of the non-susy D3 brane, under appropriate coordinate change, reduces to the Constable–Myers solution and thus confirming that this solution is indeed the holographic dual of a (non-gravitational) gauge theory discussed there. We also show that when one of the parameters of the solution takes a specific value, it reduces, under another coordinate change, to the five-dimensional solution obtained by Csaki and Reece, again confirming its gauge theory interpretation.

Neutrino oscillations from discrete non-Abelian family symmetries

International Nuclear Information System (INIS)

Schmaltz, M.

1994-11-01

The author discusses a SUSY-GUT model with a non-Abelian discrete family symmetry that explains the observed hierarchical pattern of quark and lepton masses. This SO(10) x Δ(75) model predicts modified quadratic seesaw neutrino masses and mixing angles which are interesting for three reasons: (1) they offer a solution to the solar neutrino problem, (2) the tau neutrino has the right mass for a cosmologically interesting hot dark matter candidate, and (3) they suggest a positive result for the ν μ → ν τ oscillation searches by the CHORUS and NOMAD collaborations. However, the model shares some problems with many other predictive GUT models of quark and lepton masses. Well-known and once successful mass and angle relations, such as the SU(5) relation λ b GUT = λ t GUT , are found to be in conflict with the current experimental status. Attempts to correct these relations seem to lead to rather contrived models

SLAM, a Mathematica interface for SUSY spectrum generators

International Nuclear Information System (INIS)

Marquard, Peter; Zerf, Nikolai

2013-09-01

We present and publish a Mathematica package, which can be used to automatically obtain any numerical MSSM input parameter from SUSY spectrum generators, which follow the SLHA standard, like SPheno, SOFTSUSY or Suspect. The package enables a very comfortable way of numerical evaluations within the MSSM using Mathematica. It implements easy to use predefined high scale and low scale scenarios like mSUGRA or m h max and if needed enables the user to directly specify the input required by the spectrum generators. In addition it supports an automatic saving and loading of SUSY spectra to and from a SQL data base, avoiding the rerun of a spectrum generator for a known spectrum.

Heavy colored SUSY partners from deflected anomaly mediation

Energy Technology Data Exchange (ETDEWEB)

Wang, Fei [Department of Physics and Engineering, Zhengzhou University,Zhengzhou 450000 (China); State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Academia Sinica,Beijing 100190 (China); Wang, Wenyu [Institute of Theoretical Physics, College of Applied Science, Beijing University of Technology,Beijing 100124 (China); Yang, Jin Min; Zhang, Yang [State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Academia Sinica,Beijing 100190 (China)

2015-07-27

We propose a deflected anomaly mediation scenario from SUSY QCD which can lead to both positive and negative deflection parameters (there is a smooth transition between these two deflection parameter regions by adjusting certain couplings). Such a scenario can naturally give a SUSY spectrum in which all the colored sparticles are heavy while the sleptons are light. As a result, the discrepancy between the Brookheaven g{sub μ}−2 experiment and LHC data can be reconciled in this scenario. We also find that the parameter space for explaining the g{sub μ}−2 anomaly at 1σ level can be fully covered by the future LUX-ZEPLIN 7.2 Ton experiment.

SLAM, a Mathematica interface for SUSY spectrum generators

Energy Technology Data Exchange (ETDEWEB)

Marquard, Peter [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Zerf, Nikolai [Alberta Univ., Edmonton, AB (Canada). Dept. of Physics

2013-09-15

We present and publish a Mathematica package, which can be used to automatically obtain any numerical MSSM input parameter from SUSY spectrum generators, which follow the SLHA standard, like SPheno, SOFTSUSY or Suspect. The package enables a very comfortable way of numerical evaluations within the MSSM using Mathematica. It implements easy to use predefined high scale and low scale scenarios like mSUGRA or m{sub h}{sup max} and if needed enables the user to directly specify the input required by the spectrum generators. In addition it supports an automatic saving and loading of SUSY spectra to and from a SQL data base, avoiding the rerun of a spectrum generator for a known spectrum.

Roadmap of left-right models based on GUTs

Science.gov (United States)

Chakrabortty, Joydeep; Maji, Rinku; Patra, Sunando Kumar; Srivastava, Tripurari; Mohanty, Subhendra

2018-05-01

We perform a detailed study of the grand unified theories S O (10 ) and E (6 ) with left-right intermediate gauge symmetries of the form S U (N )L⊗S U (N )R⊗G . Proton decay lifetime constrains the unification scale to be ≳1016 GeV and, as discussed in this paper, unwanted cosmological relics can be evaded if the intermediate symmetry scale is ≳1012 GeV . With these conditions, we study the renormalization group evolution of the gauge couplings and do a comparative analysis of all possible left-right models where unification can occur. Both the D-parity conserved and broken scenarios as well as the supersymmetric (SUSY) and nonsupersymmetric (non-SUSY) versions are considered. In addition to the fermion and scalar representations at each stage of the symmetry breaking, contributing to the β functions, we list the intermediate left-right groups that successfully meet these requirements. We make use of the dimension-5 kinetic mixing effective operators for achieving unification and large intermediate scale. A significant result in the supersymmetric case is that to achieve successful unification for some breaking patterns, the scale of SUSY breaking needs to be at least a few TeV. In some of these cases, the intermediate scale can be as low as ˜1012 GeV , for the SUSY scale to be ˜30 TeV . This has important consequences in the collider searches for SUSY particles and phenomenology of the lightest neutralino as dark matter.

SUSY method for the three-dimensional Schrödinger equation with effective mass

International Nuclear Information System (INIS)

Ioffe, M.V.; Kolevatova, E.V.; Nishnianidze, D.N.

2016-01-01

Highlights: • SUSY intertwining relations for the 3-dim Schrödinger equation with effective mass were studied. • The general solution of these intertwining relations with first order supercharges was obtained. • Four different options for parameters values were considered separately to find the mass functions and partner potentials. - Abstract: The three-dimensional Schrödinger equation with a position-dependent (effective) mass is studied in the framework of Supersymmetrical (SUSY) Quantum Mechanics. The general solution of SUSY intertwining relations with first order supercharges is obtained without any preliminary constraints. Several forms of coefficient functions of the supercharges are investigated and analytical expressions for the mass function and partner potentials are found. As usual for SUSY Quantum Mechanics with nonsingular superpotentials, the spectra of intertwined Hamiltonians coincide up to zero modes of supercharges, and the corresponding wave functions are connected by intertwining relations. All models are partially integrable by construction: each of them has at least one second order symmetry operator.

Constraints of chromoelectric dipole moments to natural SUSY type sfermion spectrum

Science.gov (United States)

Maekawa, Nobuhiro; Muramatsu, Yu; Shigekami, Yoshihiro

2017-06-01

We investigate the lower bounds of sfermion masses from the constraints of chromoelectric dipole moments (CEDMs) in the natural SUSY-type sfermion mass spectrum, in which stop mass mt ˜ is much smaller than the other sfermion masses m0. The natural SUSY-type sfermion mass spectrum has been studied since the supersymmetric (SUSY) flavor-changing neutral currents (FCNC) are suppressed because of large sfermion masses of the first two generations, and the weak scale is stabilized because of the light stop. However, this type of sfermion mass spectrum is severely constrained by CEDM, because the light stop contributions to the up quark CEDM are not decoupled in the limit m0→∞ , while the down quark CEDM is decoupled in the limit. It is important that the constraints are severe even if SUSY-breaking parameters (and Higgsino mass) are taken to be real because complex diagonalizing matrices of Yukawa matrices, which are from complex Yukawa couplings, generate nonvanishing C P phases in off-diagonal elements of sfermion mass matrices. We calculate the CEDM of up and down quarks numerically in the minimal SUSY standard model, and give the lower bounds for stop mass and the other sfermion masses. We show that the lower bound of stop mass becomes 7 TeV to satisfy the CEDM constraints from Hg EDM. The result is not acceptable if the weak scale stability is considered seriously. We show that if the up-type Yukawa couplings are taken to be real at the grand unification scale, the CEDM constraints are satisfied even if mt ˜˜1 TeV .

On Bimaximal Neutrino Mixing and GUT's

CERN Document Server

Altarelli, Guido; Meloni, Davide

2015-04-21

We briefly discuss the present status of models of neutrino mixing. Among the existing viable options we review the virtues of Bimaximal Mixing (that could be implemented by an $S_4$ discrete symmetry), corrected by terms arising from the charged lepton mass diagonalization. In particular in a GUT formulation the property of quark lepton "weak" complementarity can be naturally realized. We discuss in some detail two new versions of particular GUT models, one based on $SU(5)$ and one on $SO(10)$ and the associated phenomenology. We compare these approaches based on symmetry to models based on chance, like Anarchy or $U(1)_{FN}$.

Long-lived and compressed SUSY searches at CMS and ATLAS

CERN Document Server

Barlow, Nick; The ATLAS collaboration

2015-01-01

Two challenging scenarios for SUSY searches at the LHC are when there are small mass differences between particles in the decay chain ("compressed" spectra) and where the SUSY particles have a non-negligible lifetime. The compressed case can be addressed by looking at events containing Initial State Radiation (ISR), while long-lifetimes can give rise to a wide range of possible detector signatures. This talk describes these diverse and interesting searches, performed by the ATLAS and CMS collaborations on the Run 1 LHC data.

SUGRA-GUT motivated SUSY search in the dielectron channel at D0

International Nuclear Information System (INIS)

1996-09-01

In this paper we present a search for events consistent with the production and decay of supersymmetric particles in the Supergravity- GUT framework in the D null detector at Fermilab. We examine the 1994-95 Run 1B data for events containing two or more electrons, two or more jets, and a substantial missing transverse energy. This is complementary to the search in the canonical jets and missing transverse energy channel. We observe 2 events in 92.9 pb -1 or the Run 1B data consistent with the estimated total background contribution of 3.0 ± 1.3 events from the Standard Model. The non- observation of excess events has been interpreted as an excluded region on the two-dimensional m 0 - m 1/2 plane

GUT model hierarchies from intersecting branes

International Nuclear Information System (INIS)

Kokorelis, Christos

2002-01-01

By employing D6-branes intersecting at angles in D=4 type I strings, we construct three generation models with minimal structure, based on the group SU(4) C xSU(2) L xSU(2) R . The models are non-supersymmetric, even though SUSY is unbroken in the bulk, and contain at low energy the standard model spectrum augmented by an extra anomaly free global U(1) symmetry, with no extra matter and/or extra gauge group factors. Baryon number is gauged and its anomalies are cancelled through a generalized Green-Schwarz mechanism. We also show that multibrane wrappings correspond to a trivial redefinition of the surviving global U(1) at low energies. There are no colour triplet couplings to mediate proton decay, while a heavy mass for the right handed neutrinos can be generated through the see-saw mechanism. The mass relation m e =m d at the GUT scale is recovered. The presence of the right handed neutrino in the see-saw mechanism, suggests that the string scale should be of the same order as the GUT scale and at least an order of magnitude above the mass of the right handed neutrino, effectively placing the string scale above 2-3 TeV, independently of the presence of the left handed neutrino. (author)

Soft see-saw: Radiative origin of neutrino masses in SUSY theories

Directory of Open Access Journals (Sweden)

Luka Megrelidze

2017-01-01

Full Text Available Radiative neutrino mass generation within supersymmetric (SUSY construction is studied. The mechanism is considered where the lepton number violation is originating from the soft SUSY breaking terms. This requires MSSM extensions with states around the TeV scale. We present several explicit realizations based on extensions either by MSSM singlet or SU(2w triplet states. Besides some novelties of the proposed scenarios, various phenomenological implications are also discussed.

Supergravity theories

International Nuclear Information System (INIS)

Uehara, S.

1985-01-01

Of all supergravity theories, the maximal, i.e., N = 8 in 4-dimension or N = 1 in 11-dimension, theory should perform the unification since it owns the highest degree of symmetry. As to the N = 1 in d = 11 theory, it has been investigated how to compactify to the d = 4 theories. From the phenomenological point of view, local SUSY GUTs, i.e., N = 1 SUSY GUTs with soft breaking terms, have been studied from various angles. The structures of extended supergravity theories are less understood than those of N = 1 supergravity theories, and matter couplings in N = 2 extended supergravity theories are under investigation. The harmonic superspace was recently proposed which may be useful to investigate the quantum effects of extended supersymmetry and supergravity theories. As to the so-called Kaluza-Klein supergravity, there is another possibility. (Mori, K.)

Towards N = 2 SUSY homogeneous quantum cosmology; Einstein-Yang-Mills systems

International Nuclear Information System (INIS)

Donets, E.E.; Tentyukov, M.N.; Tsulaya, M.M.

1998-01-01

The application of N = 2 supersymmetric Quantum Mechanics for the quantization of homogeneous systems coupled with gravity is discussed. Starting with the superfield formulation of N = 2 SUSY sigma-model, Hermitian self-adjoint expressions for quantum Hamiltonians and Lagrangians for any signature of a sigma-model metric are obtained. This approach is then applied to coupled SU (2) Einstein-Yang-Mills (EYM) systems in axially-symmetric Bianchi - I,II,VIII, IX, Kantowski-Sachs and closed Friedmann-Robertson-Walker cosmological models. It is shown that all these models admit the embedding into N = 2 SUSY sigma-model with the explicit expressions for superpotentials, being direct sums of gravitational and Yang-Mills (YM) parts. In addition, YM parts of superpotentials exactly coincide with the corresponding Chern-Simons terms. The spontaneous SUSY breaking, caused by YM instantons in EYM systems is discussed in a number of examples

Holographic entanglement entropy and entanglement thermodynamics of 'black' non-susy D3 brane

Science.gov (United States)

Bhattacharya, Aranya; Roy, Shibaji

2018-06-01

Like BPS D3 brane, the non-supersymmetric (non-susy) D3 brane of type IIB string theory is also known to have a decoupling limit and leads to a non-supersymmetric AdS/CFT correspondence. The throat geometry in this case represents a QFT which is neither conformal nor supersymmetric. The 'black' version of the non-susy D3 brane in the decoupling limit describes a QFT at finite temperature. Here we first compute the entanglement entropy for small subsystem of such QFT from the decoupled geometry of 'black' non-susy D3 brane using holographic technique. Then we study the entanglement thermodynamics for the weakly excited states of this QFT from the asymptotically AdS geometry of the decoupled 'black' non-susy D3 brane. We observe that for small subsystem this background indeed satisfies a first law like relation with a universal (entanglement) temperature inversely proportional to the size of the subsystem and an (entanglement) pressure normal to the entangling surface. Finally we show how the entanglement entropy makes a cross-over to the thermal entropy at high temperature.

Implications of low and high energy measurements on SUSY models

Energy Technology Data Exchange (ETDEWEB)

Jegerlehner, Fred [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik

2012-04-15

New Physics searches at the LHC have increased significantly lower bounds on unknown particle masses. This increases quite dramatically the tension in the interpretation of the data: low energy precision data which are predicted accurately by the SM (LEP observables like M{sub W} or loop induced rare processes like B {yields}X{sub s}{gamma} or B{sub s}{yields}{mu}{sup +}{mu}{sup -}) and quantities exhibiting an observed discrepancy between SM theory and experiment, most significantly found for the muon g-2 seem to be in conflict now. (g-2){sub {mu}} appears to be the most precisely understood observable which at the same time reveals a 3-4 {sigma} deviation between theory and experiment and thus requires a significant new physics contribution. The hints for a Higgs of mass about 125 GeV, which is precisely what SUSY extensions of the SM predict, seem to provide a strong indication for SUSY. At the same time it brings into serious trouble the interpretation of the (g-2){sub {mu}} deviation as a SUSY contribution.

Search for SUSY in the AMSB scenario with the DELPHI detector

CERN Document Server

Abdallah, J.; Adam, W.; Adzic, P.; Albrecht, T.; Alderweireld, T.; Alemany-Fernandez, R.; Allmendinger, T.; Allport, P.P.; Amaldi, U.; Amapane, N.; Amato, S.; Anashkin, E.; Andreazza, A.; Andringa, S.; Anjos, N.; Antilogus, P.; Apel, W.D.; Arnoud, Y.; Ask, S.; Asman, B.; Augustin, J.E.; Augustinus, A.; Baillon, P.; Ballestrero, A.; Bambade, P.; Barbier, R.; Bardin, D.; Barker, G.; Baroncelli, A.; Battaglia, M.; Baubillier, M.; Becks, K.H.; Begalli, M.; Behrmann, A.; Ben-Haim, E.; Benekos, N.; Benvenuti, A.; Berat, C.; Berggren, M.; Berntzon, L.; Bertrand, D.; Besancon, M.; Besson, N.; Bloch, D.; Blom, M.; Bluj, M.; Bonesini, M.; Boonekamp, M.; Booth, P.S.L.; Borisov, G.; Botner, O.; Bouquet, B.; Bowcock, T.J.V.; Boyko, I.; Bracko, M.; Brenner, R.; Brodet, E.; Bruckman, P.; Brunet, J.M.; Bugge, L.; Buschmann, P.; Calvi, M.; Camporesi, T.; Canale, V.; Carena, F.; Castro, Nuno Filipe; Cavallo, F.; Chapkin, M.; Charpentier, Ph.; Checchia, P.; Chierici, R.; Chliapnikov, P.; Chudoba, J.; Chung, S.U.; Cieslik, K.; Collins, P.; Contri, R.; Cosme, G.; Cossutti, F.; Costa, M.J.; Crennell, D.; Cuevas, J.; D'Hondt, J.; Dalmau, J.; da Silva, T.; Da Silva, W.; Della Ricca, G.; De Angelis, A.; De Boer, W.; De Clercq, C.; De Lotto, B.; De Maria, N.; De Min, A.; de Paula, L.; Di Ciaccio, L.; Di Simone, A.; Doroba, K.; Drees, J.; Dris, M.; Eigen, G.; Ekelof, T.; Ellert, M.; Elsing, M.; Espirito Santo, M.C.; Fanourakis, G.; Fassouliotis, D.; Feindt, M.; Fernandez, J.; Ferrer, A.; Ferro, F.; Flagmeyer, U.; Foeth, H.; Fokitis, E.; Fulda-Quenzer, F.; Fuster, J.; Gandelman, M.; Garcia, C.; Gavillet, Ph.; Gazis, Evangelos; Gokieli, R.; Golob, B.; Gomez-Ceballos, G.; Goncalves, P.; Graziani, E.; Grosdidier, G.; Grzelak, K.; Guy, J.; Haag, C.; Hallgren, A.; Hamacher, K.; Hamilton, K.; Haug, S.; Hauler, F.; Hedberg, V.; Hennecke, M.; Herr, H.; Hoffman, J.; Holmgren, S.O.; Holt, P.J.; Houlden, M.A.; Hultqvist, K.; Jackson, John Neil; Jarlskog, G.; Jarry, P.; Jeans, D.; Johansson, Erik Karl; Johansson, P.D.; Jonsson, P.; Joram, C.; Jungermann, L.; Kapusta, Frederic; Katsanevas, S.; Katsoufis, E.; Kernel, G.; Kersevan, B.P.; Kerzel, U.; Kiiskinen, A.; King, B.T.; Kjaer, N.J.; Kluit, P.; Kokkinias, P.; Kourkoumelis, C.; Kouznetsov, O.; Krumstein, Z.; Kucharczyk, M.; Lamsa, J.; Leder, G.; Ledroit, Fabienne; Leinonen, L.; Leitner, R.; Lemonne, J.; Lepeltier, V.; Lesiak, T.; Liebig, W.; Liko, D.; Lipniacka, A.; Lopes, J.H.; Lopez, J.M.; Loukas, D.; Lutz, P.; Lyons, L.; MacNaughton, J.; Malek, A.; Maltezos, S.; Mandl, F.; Marco, J.; Marco, R.; Marechal, B.; Margoni, M.; Marin, J.C.; Mariotti, C.; Markou, A.; Martinez-Rivero, C.; Masik, J.; Mastroyiannopoulos, N.; Matorras, F.; Matteuzzi, C.; Mazzucato, F.; Mazzucato, M.; McNulty, R.; Meroni, C.; Migliore, E.; Mitaroff, W.; Mjoernmark, U.; Moa, T.; Moch, M.; Monig, Klaus; Monge, R.; Montenegro, J.; Moraes, D.; Moreno, S.; Morettini, P.; Mueller, U.; Muenich, K.; Mulders, M.; Mundim, L.; Murray, W.; Muryn, B.; Myatt, G.; Myklebust, T.; Nassiakou, M.; Navarria, F.; Nawrocki, K.; Nicolaidou, R.; Nikolenko, M.; Oblakowska-Mucha, A.; Obraztsov, V.; Olshevski, A.; Onofre, A.; Orava, R.; Osterberg, K.; Ouraou, A.; Oyanguren, A.; Paganoni, M.; Paiano, S.; Palacios, J.P.; Palka, H.; Papadopoulou, Th.D.; Pape, L.; Parkes, C.; Parodi, F.; Parzefall, U.; Passeri, A.; Passon, O.; Peralta, L.; Perepelitsa, V.; Perrotta, A.; Petrolini, A.; Piedra, J.; Pieri, L.; Pierre, F.; Pimenta, M.; Piotto, E.; Podobnik, T.; Poireau, V.; Pol, M.E.; Polok, G.; Poropat, P.; Pozdniakov, V.; Pukhaeva, N.; Pullia, A.; Rames, J.; Ramler, L.; Read, Alexander L.; Rebecchi, P.; Rehn, J.; Reid, D.; Reinhardt, R.; Renton, P.; Richard, F.; Ridky, J.; Rivero, M.; Rodriguez, D.; Romero, A.; Ronchese, P.; Roudeau, P.; Rovelli, T.; Ruhlmann-Kleider, V.; Ryabtchikov, D.; Sadovsky, A.; Salmi, L.; Salt, J.; Savoy-Navarro, A.; Schwickerath, U.; Segar, A.; Sekulin, R.; Siebel, M.; Sisakian, A.; Smadja, G.; Smirnova, O.; Sokolov, A.; Sopczak, A.; Sosnowski, R.; Spassov, T.; Stanitzki, M.; Stocchi, A.; Strauss, J.; Stugu, B.; Szczekowski, M.; Szeptycka, M.; Szumlak, T.; Tabarelli, T.; Taffard, A.C.; Tegenfeldt, F.; Timmermans, Jan; Tkatchev, L.; Tobin, M.; Todorovova, S.; Tome, B.; Tonazzo, A.; Tortosa, P.; Travnicek, P.; Treille, D.; Tristram, G.; Trochimczuk, M.; Troncon, C.; Turluer, M.L.; Tyapkin, I.A.; Tyapkin, P.; Tzamarias, S.; Uvarov, V.; Valenti, G.; Van Dam, Piet; Van Eldik, J.; Van Lysebetten, A.; van Remortel, N.; Van Vulpen, I.; Vegni, G.; Veloso, F.; Venus, W.; Verdier, P.; Verzi, V.; Vilanova, D.; Vitale, L.; Vrba, V.; Wahlen, H.; Washbrook, A.J.; Weiser, C.; Wicke, D.; Wickens, J.; Wilkinson, G.; Winter, M.; Witek, M.; Yushchenko, O.; Zalewska, A.; Zalewski, P.; Zavrtanik, D.; Zhuravlov, V.; Zimine, N.I.; Zintchenko, A.; Zupan, M.

2004-01-01

The DELPHI experiment at the LEP e+e- collider collected almost 700 pb^-1 at centre-of-mass energies above the Z0 mass pole and up to 208 GeV. Those data were used to search for SUSY in the Anomaly Mediated SUSY Breaking (AMSB) scenario with a flavour independent common sfermion mass parameter. The searches covered several possible signatures experimentally accessible at LEP, with either the neutralino, the sneutrino or the stau being the Lightest Supersymmetric Particle (LSP). They included: the search for nearly mass-degenerate chargino and neutralino, which is a typical feature of AMSB; the search for Standard-Model-like or invisibly decaying Higgs boson; the search for stable staus; the search for cascade decays of SUSY particles resulting in the LSP and a low multiplicity final state containing neutrinos. No evidence of a signal was found, and thus constraints were set in the space of the parameters of the model.

The SUSY oscillator from local geometry: Dynamics and coherent states

International Nuclear Information System (INIS)

Thienel, H.P.

1994-01-01

The choice of a coordinate chart on an analytical R n (R a n ) provides a representation of the n-dimensional SUSY oscillator. The corresponding Hilbert space is Cartan's exterior algebra endowed with a suitable scalar product. The exterior derivative gives rise to the algebra of the n-dimensional SUSY oscillator. Its euclidean dynamics is an inherent consequence of the geometry imposed by the Lie derivative generating the dilations, i.e. evolution of the quantum system corresponds to parametrization of a sequence of charts by euclidean time. Coherent states emerge as a natural structure related to the Lie derivative generating the translations. (orig.)

Precision natural SUSY at CEPC, FCC-ee, and ILC

International Nuclear Information System (INIS)

Fan, JiJi; Reece, Matthew; Wang, Lian-Tao

2015-01-01

Testing the idea of naturalness is and will continue to be one of the most important goals of high energy physics experiments. It will play a central role in the physics program of future colliders. In this paper, we present projections of the reach of natural SUSY at future lepton colliders: CEPC, FCC-ee and ILC. We focus on the observables which give the strongest reach, the electroweak precision observables (for left-handed stops), and Higgs to gluon and photon decay rates (for both left- and right-handed stops). There is a “blind spot” when the stop mixing parameter X t is approximately equal to the average stop mass. We argue that in natural scenarios, bounds on the heavy Higgs bosons from tree-level mixing effects that modify the hbb̄ coupling together with bounds from b→sγ play a complementary role in probing the blind spot region. For specific natural SUSY scenarios such as folded SUSY in which the top partners do not carry Standard Model color charges, electroweak precision observables could be the most sensitive probe. In all the scenarios discussed in this paper, the combined set of precision measurements will probe down to a few percent in fine-tuning.

Deletion analysis of susy-sl promoter for the identification of optimal promoter sequence

International Nuclear Information System (INIS)

Bacha, S.; Khatoon, A.; Asif, M.; Bshir, A.

2015-01-01

The promoter region of sucrose synthase (susy-Sl) was identified and isolated from tomato. The 5? deletion analysis was carried out for the identification of minimum optimal promoter. Transgenic lines of Arabidopsis thaliana were developed by floral dip method incorporating various promoter deletion cassettes controlling GUS reporter gene. GUS assay of transgenic tissues indicated that full length susy-Sl promoter and its deletion mutants were constitutively expressed in vegetative and floral tissues of A. thaliana. The expression was observed in roots, shoots and flowers of A. thaliana. Analysis of 5? deletion series of susy-Sl promoter showed that a minimum of 679 bp fragment of the promoter was sufficient to drive expression of GUS reporter gene in the major tissues of transgenic A. thaliana. (author)

Yukawa sector of minimal SO(10) unification

Energy Technology Data Exchange (ETDEWEB)

Babu, K.S. [Department of Physics, Oklahoma State University,Stillwater, OK, 74078 (United States); Bajc, Borut [Jožef Stefan Institute,Ljubljana, 1000 (Slovenia); Saad, Shaikh [Department of Physics, Oklahoma State University,Stillwater, OK, 74078 (United States)

2017-02-28

We show that in SO(10) models, a Yukawa sector consisting of a real 10{sub H}, a real 120{sub H} and a complex 126{sub H} of Higgs fields can provide a realistic fit to all fermion masses and mixings, including the neutrino sector. Although the group theory of SO(10) demands that the 10{sub H} and 120{sub H} be real, most constructions complexify these fields and impose symmetries exterior to SO(10) to achieve predictivity. The proposed new framework with real10{sub H} and real120{sub H} relies only on SO(10) gauge symmetry, and yet has a limited number of Yukawa parameters. Our analysis shows that while there are restrictions on the observables, a good fit to the entire fermion spectrum can be realized. Unification of gauge couplings is achieved with an intermediate scale Pati-Salam gauge symmetry. Proton decay branching ratios are calculable, with the leading decay modes being p→ν̄π{sup +} and p→e{sup +}π{sup 0}.

Vast antimatter regions and SUSY-condensate baryogenesis

International Nuclear Information System (INIS)

Kirilova, D.; Panayotova, M.; Valchanov, T.

2002-10-01

Natural and abundant creation of antimatter in the Universe in a SUSY baryogenesis model is described. The scenario predicts vast quantities of antimatter, corresponding to galaxy and galaxy cluster scales, separated from the matter ones by baryonically empty voids. Observational constraints on such antimatter regions are discussed. (author)

Search for Higgs Bosons in SUSY Cascades in CMS and Dark Matter with Non-universal Gaugino Masses

CERN Document Server

Huitu, Katri; Laamanen, Jari; Lehti, Sami; Roy, Sourov; Salminen, Tapio

2008-01-01

In grand unified theories (GUT), non-universal boundary conditions for the gaugino masses may arise at the unification scale, and affect the observability of the neutral MSSM Higgs bosons (h/H/A) at the LHC. The implications of such non-universal gaugino masses are investigated for the Higgs boson production in the SUSY cascade decay chain gluino --> squark quark, squark --> neutralino_2 quark, neutralino_2 --> neutralino_1 h/H/A, h/H/A --> b b-bar produced in pp interactions. In the singlet representation with universal gaugino masses only the light Higgs boson can be produced in this cascade with the parameter region of interest for us, while with non-universal gaugino masses heavy neutral MSSM Higgs boson production may dominate. The allowed parameter space in the light of the WMAP constraints on the cold dark matter relic density is investigated in the above scenarios for gaugino mass parameters. We also demonstrate that combination of representations can give the required amount of dark matter in any poi...

The fine-tuning cost of the likelihood in SUSY models

International Nuclear Information System (INIS)

Ghilencea, D.M.; Ross, G.G.

2013-01-01

In SUSY models, the fine-tuning of the electroweak (EW) scale with respect to their parameters γ i ={m 0 ,m 1/2 ,μ 0 ,A 0 ,B 0 ,…} and the maximal likelihood L to fit the experimental data are usually regarded as two different problems. We show that, if one regards the EW minimum conditions as constraints that fix the EW scale, this commonly held view is not correct and that the likelihood contains all the information about fine-tuning. In this case we show that the corrected likelihood is equal to the ratio L/Δ of the usual likelihood L and the traditional fine-tuning measure Δ of the EW scale. A similar result is obtained for the integrated likelihood over the set {γ i }, that can be written as a surface integral of the ratio L/Δ, with the surface in γ i space determined by the EW minimum constraints. As a result, a large likelihood actually demands a large ratio L/Δ or equivalently, a small χ new 2 =χ old 2 +2lnΔ. This shows the fine-tuning cost to the likelihood (χ new 2 ) of the EW scale stability enforced by SUSY, that is ignored in data fits. A good χ new 2 /d.o.f.≈1 thus demands SUSY models have a fine-tuning amount Δ≪exp(d.o.f./2), which provides a model-independent criterion for acceptable fine-tuning. If this criterion is not met, one can thus rule out SUSY models without a further χ 2 /d.o.f. analysis. Numerical methods to fit the data can easily be adapted to account for this effect.

Study of SUSY particles properties at the future International Linear Collider with the International Large Detector

International Nuclear Information System (INIS)

Wichmann, K.

2009-01-01

Recently, Letters of Intent (LoI) for experiments at the International Linear Collider (ILC) have been submitted. Among the three proposals is the International Large Detector (ILD) concept which is at the focus of these studies. From various subjects addressed in the LoI, a wide spectrum of studies of SUSY particle properties is presented here. Most of them are benchmark reactions for the ILC and can be used both in physics studies and in work on detector design and optimization, respectively. All studies were performed with a full detector simulation using GEANT4, which is a great improvement compared to the previous results with much less detailed, so called f ast , simulation (SIMDET). The importance of this improved simulation is reflected in the results. The presented analyzes have been chosen to be the most challenging for the detector to study its performance and guide the detector development. Additionally an important problem of unavoidable beam induced backgrounds at linear colliders is addressed and ways of reducing its impact on physics studies are shown for an example SUSY analysis. (author)

SUSI 62 A ROBUST AND SAFE PARACHUTE UAV WITH LONG FLIGHT TIME AND GOOD PAYLOAD

Directory of Open Access Journals (Sweden)

H. P. Thamm

2012-09-01

Full Text Available In many research areas in the geo-sciences (erosion, land use, land cover change, etc. or applications (e.g. forest management, mining, land management etc. there is a demand for remote sensing images of a very high spatial and temporal resolution. Due to the high costs of classic aerial photo campaigns, the use of a UAV is a promising option for obtaining the desired remote sensed information at the time it is needed. However, the UAV must be easy to operate, safe, robust and should have a high payload and long flight time. For that purpose, the parachute UAV SUSI 62 was developed. It consists of a steel frame with a powerful 62 cm3 2- stroke engine and a parachute wing. The frame can be easily disassembled for transportation or to replace parts. On the frame there is a gimbal mounted sensor carrier where different sensors, standard SLR cameras and/or multi-spectral and thermal sensors can be mounted. Due to the design of the parachute, the SUSI 62 is very easy to control. Two different parachute sizes are available for different wind speed conditions. The SUSI 62 has a payload of up to 8 kg providing options to use different sensors at the same time or to extend flight duration. The SUSI 62 needs a runway of between 10 m and 50 m, depending on the wind conditions. The maximum flight speed is approximately 50 km/h. It can be operated in a wind speed of up to 6 m/s. The design of the system utilising a parachute UAV makes it comparatively safe as a failure of the electronics or the remote control only results in the UAV coming to the ground at a slow speed. The video signal from the camera, the GPS coordinates and other flight parameters are transmitted to the ground station in real time. An autopilot is available, which guarantees that the area of investigation is covered at the desired resolution and overlap. The robustly designed SUSI 62 has been used successfully in Europe, Africa and Australia for scientific projects and also for

Neutrino physics and the flavor problem

International Nuclear Information System (INIS)

King, S. F.; Peddie, I. N. R.

2004-01-01

We consider the problem of trying to understand the recently measured neutrino data simultaneously with understanding the hierarchical form of quark and charged-lepton Yukawa matrices. We summarize the data that a successful model of neutrino mass must predict, and then move on to attempting to do so in the context of spontaneously broken 'family' symmetries. We consider first an abelian U(1) family symmetry, which appears in the context of a type-I string model. Then we consider a model based on a non-abelian SU(3) F , which is the maximal family group consistent with an SO(10) GUT. In this case, the symmetry is more constraining, and is examined in the context of SUSY field theory.

Prospects for R-Parity Conserving SUSY searches at the LHC

CERN Document Server

Genest, Marie-Helene

2009-01-01

We review the current strategies to search for generic SUSY models with R-parity conservation in the ATLAS and CMS detectors at the LHC. The discovery reach in early data will be presented for the different search channels based on missing transverse momentum from undetected neutralinos and multiple jets. We will also describe the search for models of gauge-mediated supersymmetry breaking for which the NLSP is a neutralino decaying to a photon and a gravitino. Finally, we will present recent work on techniques used to reconstruct the decays of SUSY particles at the LHC in early data, based on the selection of final-state exclusive decay chains.

Reconstruction of tau leptons and prospects for SUSY in ATLAS

International Nuclear Information System (INIS)

Zendler, Carolin

2010-01-01

Final states with tau leptons may play a special role among the broad variety of signatures for the production of supersymmetric particles at the LHC. The algorithms for tau reconstruction and identification are discussed, which are essential ingredients to reject the huge background from QCD processes. The status of analyses of SUSY tau lepton final states within the ATLAS experiment at the LHC are presented, which range from a study of semi-inclusive discovery prospects to more exclusive processes with two tau leptons from χ-tilde 2 0 decays and their implications for the determination of SUSY parameters. Also, the prospects for exploiting tau lepton polarization are discussed.

Impact of physical properties at very high energy scales on the superparticle mass spectrum

International Nuclear Information System (INIS)

Baer, H.; Diaz, M.; Quintana, P.; Tata, X.

2000-01-01

We survey a variety of proposals for new physics at high scales that serve to relate the multitude of soft supersymmetry breaking parameters of the MSSM. We focus on models where the new physics results in non-universal soft parameters, in sharp contrast with the usually assumed mSUGRA framework. These include (i) SU(5) and SO(10) grand unified (GUT) models, (ii) the MSSM plus a right-handed neutrino, (iii) models with effective supersymmetry, (iv) models with anomaly-mediated SUSY breaking and gaugino mediated SUSY breaking, (v) models with non-universal soft terms due to string dynamics, and (vi) models based on M-theory. We outline the physics behind these models, point out some distinctive features of the weak scale sparticle spectrum, and allude to implications for collider experiments. To facilitate future studies, for each of these scenarios, we describe how collider events can be generated using the program ISAJET. Our hope is that detailed studies of a variety of alternatives will help point to the physics underlying SUSY breaking and how this is mediated to the observable sector, once sparticles are discovered and their properties measured. (author)

SUSY breaking mediation mechanisms and (g-2)μ, B→Xsγ, B→Xsl+l- and Bs→μ+μ-

International Nuclear Information System (INIS)

Baek, Seungwon; Ko, P.; Song, Wan Young

2003-01-01

We show that there are qualitative differences in correlations among (g-2)μ, B→X s γ, B→X l + l - and B s →μ + μ - in various SUSY breaking mediation mechanisms: minimal supergravity (mSUGRA), gauge mediation (GMSB), anomaly mediation (AMSB), guagino mediation (g-tildeMSB), weakly and strongly interacting string theories, and D brane models. After imposing the direct search limits on the Higgs boson and SUSY particle search limits and B→X s γ branching ratio, we find all the scenarios can accommodate the aμ≡(g-2)μ/2 in the range of (a few tens) x 10 -10 , and predict that the branching ratio for B→X s l + l - can differ from the standard model (SM) prediction by ±20% but no more. On the other hand, the B s →μ + μ - is sensitive to the SUSY breaking mediation mechanisms through the pseudoscalar and stop masses (m A and mt-tilde 1 ), and the stop mixing angle. In the GMSB with a small messenger number, the AMSB, the g-tildeMSB and the noscale scenarios, one finds that B(B s →μ + μ - ) -8 , which is below the search limit at the Tevatron Run II. Only the mSUGRA or string inspired models can generate a large branching ratio for this decay. (author)

Identifying fake leptons in ATLAS while hunting SUSY in 8 TeV proton-proton collisions

CERN Document Server

Gillam, Thomas P S

For several theoretically and experimentally motivated reasons, super- symmetry (SUSY) has for some time been identified as an interesting candidate for a theory of fundamental particle physics beyond the Stan- dard Model. The ATLAS collaboration, of which I am a member, possess a detector emplaced in the Large Hadron Collider experiment at CERN. If SUSY does in fact describe our universe, then it is hoped that evidence of it will be visible in data collected in the ATLAS detector. I present an analysis looking for a particular signature that could indicate the presence of SUSY; events containing two like-charge leptons (e or μ). This signature benefits from having both low Standard Model backgrounds as well as potential to observe several SUSY scenarios, par- ticularly those involving strong production processes. These include pair production of squarks and gluinos. The latter of these are particularly relevant for the analysis presented herein since gluinos are Majorana fermions; hence they can decay to...

On a generalized Dirac oscillator interaction for the nonrelativistic limit 3 D generalized SUSY model oscillator Hamiltonian of Celka and Hussin

International Nuclear Information System (INIS)

Jayaraman, Jambunatha; Lima Rodrigues, R. de

1994-01-01

In the context of the 3 D generalized SUSY model oscillator Hamiltonian of Celka and Hussin (CH), a generalized Dirac oscillator interaction is studied, that leads, in the non-relativistic limit considered for both signs of energy, to the CH's generalized 3 D SUSY oscillator. The relevance of this interaction to the CH's SUSY model and the SUSY breaking dependent on the Wigner parameter is brought out. (author). 6 refs

The BSM-AI project: SUSY-AI-generalizing LHC limits on supersymmetry with machine learning

Energy Technology Data Exchange (ETDEWEB)

Caron, Sascha [Radboud Universiteit, Institute for Mathematics, Astro- and Particle Physics IMAPP, Nijmegen (Netherlands); Nikhef, Amsterdam (Netherlands); Kim, Jong Soo [UAM/CSIC, Instituto de Fisica Teorica, Madrid (Spain); Rolbiecki, Krzysztof [UAM/CSIC, Instituto de Fisica Teorica, Madrid (Spain); University of Warsaw, Faculty of Physics, Warsaw (Poland); Ruiz de Austri, Roberto [IFIC-UV/CSIC, Instituto de Fisica Corpuscular, Valencia (Spain); Stienen, Bob [Radboud Universiteit, Institute for Mathematics, Astro- and Particle Physics IMAPP, Nijmegen (Netherlands)

2017-04-15

A key research question at the Large Hadron Collider is the test of models of new physics. Testing if a particular parameter set of such a model is excluded by LHC data is a challenge: it requires time consuming generation of scattering events, simulation of the detector response, event reconstruction, cross section calculations and analysis code to test against several hundred signal regions defined by the ATLAS and CMS experiments. In the BSM-AI project we approach this challenge with a new idea. A machine learning tool is devised to predict within a fraction of a millisecond if a model is excluded or not directly from the model parameters. A first example is SUSY-AI, trained on the phenomenological supersymmetric standard model (pMSSM). About 300, 000 pMSSM model sets - each tested against 200 signal regions by ATLAS - have been used to train and validate SUSY-AI. The code is currently able to reproduce the ATLAS exclusion regions in 19 dimensions with an accuracy of at least 93%. It has been validated further within the constrained MSSM and the minimal natural supersymmetric model, again showing high accuracy. SUSY-AI and its future BSM derivatives will help to solve the problem of recasting LHC results for any model of new physics. SUSY-AI can be downloaded from http://susyai.hepforge.org/. An on-line interface to the program for quick testing purposes can be found at http://www.susy-ai.org/. (orig.)

The BSM-AI project: SUSY-AI-generalizing LHC limits on supersymmetry with machine learning

International Nuclear Information System (INIS)

Caron, Sascha; Kim, Jong Soo; Rolbiecki, Krzysztof; Ruiz de Austri, Roberto; Stienen, Bob

2017-01-01

A key research question at the Large Hadron Collider is the test of models of new physics. Testing if a particular parameter set of such a model is excluded by LHC data is a challenge: it requires time consuming generation of scattering events, simulation of the detector response, event reconstruction, cross section calculations and analysis code to test against several hundred signal regions defined by the ATLAS and CMS experiments. In the BSM-AI project we approach this challenge with a new idea. A machine learning tool is devised to predict within a fraction of a millisecond if a model is excluded or not directly from the model parameters. A first example is SUSY-AI, trained on the phenomenological supersymmetric standard model (pMSSM). About 300, 000 pMSSM model sets - each tested against 200 signal regions by ATLAS - have been used to train and validate SUSY-AI. The code is currently able to reproduce the ATLAS exclusion regions in 19 dimensions with an accuracy of at least 93%. It has been validated further within the constrained MSSM and the minimal natural supersymmetric model, again showing high accuracy. SUSY-AI and its future BSM derivatives will help to solve the problem of recasting LHC results for any model of new physics. SUSY-AI can be downloaded from http://susyai.hepforge.org/. An on-line interface to the program for quick testing purposes can be found at http://www.susy-ai.org/. (orig.)

Prospects for SUSY discovery based on inclusive searches with the ATLAS detector

International Nuclear Information System (INIS)

Ventura, Andrea

2009-01-01

The search for Supersymmetry (SUSY) among the possible scenarios of new physics is one of the most relevant goals of the ATLAS experiment running at CERN's Large Hadron Collider. In the present work the expected prospects for discovering SUSY with the ATLAS detector are reviewed, in particular for the first fb -1 of collected integrated luminosity. All studies and results reported here are based on inclusive search analyses realized with Monte Carlo signal and background data simulated through the ATLAS apparatus.

Recent results on SUSY searches from CMS

CERN Multimedia

CERN. Geneva

2013-01-01

The latest results on searches for Supersymmetry from CMS are reviewed. We present searches for direct stop production, searches in final states with four W bosons and multiple b-quarks, and searches for R-Parity violating SUSY. The results use up to 20/fb of data from the 8 TeV LHC run of 2012.

GUTs on Compact Type IIB Orientifolds

Energy Technology Data Exchange (ETDEWEB)

Blumenhagen, Ralph; /Munich, Max Planck Inst.; Braun, Volker; /Dublin Inst.; Grimm, Thomas W.; /Bonn U.; Weigand, Timo; /SLAC

2008-12-01

We systematically analyze globally consistent SU(5) GUT models on intersecting D7-branes in genuine Calabi-Yau orientifolds with O3- and O7-planes. Beyond the well-known tadpole and K-theory cancellation conditions there exist a number of additional subtle but quite restrictive constraints. For the realization of SU(5) GUTs with gauge symmetry breaking via U(1)Y flux we present two classes of suitable Calabi-Yau manifolds defined via del Pezzo transitions of the elliptically fibred hypersurface P{sub 1,1,1,6,9}[18] and of the Quintic P{sub 1,1,1,1,1}[5], respectively. To define an orientifold projection we classify all involutions on del Pezzo surfaces. We work out the model building prospects of these geometries and present five globally consistent string GUT models in detail, including a 3-generation SU(5) model with no exotics whatsoever. We also realize other phenomenological features such as the 10 10 5{sub H} Yukawa coupling and comment on the possibility of moduli stabilization, where we find an entire new set of so-called swiss-cheese type Calabi-Yau manifolds. It is expected that both the general constrained structure and the concrete models lift to F-theory vacua on compact Calabi-Yau fourfolds.

Concordia elas tuleviku arvelt / Mart Susi ; interv. Krister Kivi

Index Scriptorium Estoniae

Susi, Mart, 1965-

2003-01-01

Ilmunud ka: Infopress 21. märts nr. 12 lk. 30-31. Concordia Ülikooli rektor Mart Susi räägib kooli senisest juhtimisest ning asjaoludest, mis on põhjustanud pankroti. Tabel: Concordia kronoloogia

An SO(10) × SO(10)' model for common origin of neutrino masses, ordinary and dark matter-antimatter asymmetries

International Nuclear Information System (INIS)

Gu, Pei-Hong

2014-01-01

We propose an SO(10) × SO(10)' model to simultaneously realize a seesaw for Dirac neutrino masses and a leptogenesis for ordinary and dark matter-antimatter asymmetries. A (16 × 1-bar 6-bar ') H scalar crossing the SO(10) and SO(10)' sectors plays an essential role in this seesaw-leptogenesis scenario. As a result of lepton number conservation, the lightest dark nucleon as the dark matter particle should have a determined mass around 15 GeV to explain the comparable fractions of ordinary and dark matter in the present universe. The (16 × 1-bar 6-bar ') H scalar also mediates a U(1) em × U(1)' em kinetic mixing after the ordinary and dark left-right symmetry breaking so that we can expect a dark nucleon scattering in direct detection experiments and/or a dark nucleon decay in indirect detection experiments. Furthermore, we can impose a softly broken mirror symmetry to simplify the parameter choice

Initial conditions for inflation and the energy scale of SUSY-breaking from the (nearly) gaussian sky

CERN Document Server

Álvarez-Gaumé, Luis; Jimenez, Raul

We show how general initial conditions for small field inflation can be obtained in multi-field models. This is provided by non-linear angular friction terms in the inflaton that provide a phase of non-slow-roll inflation before the slow-roll inflation phase. This in turn provides a natural mechanism to star small-field slow-roll at nearly zero velocity for arbitrary initial conditions. We also show that there is a relation between the scale of SUSY breaking sqrt (f) and the amount of non-gaussian fluctuations generated by the inflaton. In particular, we show that in the local non-gaussian shape there exists the relation sqrt (f) = 10^{13} GeV sqrt (f_NL). With current observational limits from Planck, and adopting the minimum amount of non-gaussian fluctuations allowed by single-field inflation, this provides a very tight constraint for the SUSY breaking energy scale sqrt (f) = 3-7 x 10^{13} GeV at 95% confidence. Further limits, or detection, from next year's Planck polarisation data will further tighten th...

High-frequency spectral ultrasound imaging (SUSI) visualizes early post-traumatic heterotopic ossification (HO) in a mouse model.

Science.gov (United States)

Ranganathan, Kavitha; Hong, Xiaowei; Cholok, David; Habbouche, Joe; Priest, Caitlin; Breuler, Christopher; Chung, Michael; Li, John; Kaura, Arminder; Hsieh, Hsiao Hsin Sung; Butts, Jonathan; Ucer, Serra; Schwartz, Ean; Buchman, Steven R; Stegemann, Jan P; Deng, Cheri X; Levi, Benjamin

2018-04-01

Early treatment of heterotopic ossification (HO) is currently limited by delayed diagnosis due to limited visualization at early time points. In this study, we validate the use of spectral ultrasound imaging (SUSI) in an animal model to detect HO as early as one week after burn tenotomy. Concurrent SUSI, micro CT, and histology at 1, 2, 4, and 9weeks post-injury were used to follow the progression of HO after an Achilles tenotomy and 30% total body surface area burn (n=3-5 limbs per time point). To compare the use of SUSI in different types of injury models, mice (n=5 per group) underwent either burn/tenotomy or skin incision injury and were imaged using a 55MHz probe on VisualSonics VEVO 770 system at one week post injury to evaluate the ability of SUSI to distinguish between edema and HO. Average acoustic concentration (AAC) and average scatterer diameter (ASD) were calculated for each ultrasound image frame. Micro CT was used to calculate the total volume of HO. Histology was used to confirm bone formation. Using SUSI, HO was visualized as early as 1week after injury. HO was visualized earliest by 4weeks after injury by micro CT. The average acoustic concentration of HO was 33% more than that of the control limb (n=5). Spectroscopic foci of HO present at 1week that persisted throughout all time points correlated with the HO present at 9weeks on micro CT imaging. SUSI visualizes HO as early as one week after injury in an animal model. SUSI represents a new imaging modality with promise for early diagnosis of HO. Copyright © 2018 Elsevier Inc. All rights reserved.

Cosmological constant in SUGRA models with Planck scale SUSY breaking and degenerate vacua

International Nuclear Information System (INIS)

Froggatt, C.D.; Nevzorov, R.; Nielsen, H.B.; Thomas, A.W.

2014-01-01

The empirical mass of the Higgs boson suggests small to vanishing values of the quartic Higgs self-coupling and the corresponding beta function at the Planck scale, leading to degenerate vacua. This leads us to suggest that the measured value of the cosmological constant can originate from supergravity (SUGRA) models with degenerate vacua. This scenario is realised if there are at least three exactly degenerate vacua. In the first vacuum, associated with the physical one, local supersymmetry (SUSY) is broken near the Planck scale while the breakdown of the SU(2) W ×U(1) Y symmetry takes place at the electroweak (EW) scale. In the second vacuum local SUSY breaking is induced by gaugino condensation at a scale which is just slightly lower than Λ QCD in the physical vacuum. Finally, in the third vacuum local SUSY and EW symmetry are broken near the Planck scale

SUSY formalism for the symmetric double well potential

Indian Academy of Sciences (India)

symmetric double well potential barrier we have obtained a class of exactly solvable potentials subject to moving boundary condition. The eigenstates are also obtained by the same technique. Keywords. SUSY; moving boundary condition; exactly solvable; symmetric double well; NH3 molecule. PACS Nos 02.30.Ik; 03.50.

Understanding the gut microbiome of dairy calves: Opportunities to improve early-life gut health.

Science.gov (United States)

Malmuthuge, Nilusha; Guan, Le Luo

2017-07-01

Early gut microbiota plays a vital role in the long-term health of the host. However, understanding of these microbiota is very limited in livestock species, especially in dairy calves. Neonatal calves are highly susceptible to enteric infections, one of the major causes of calf death, so approaches to improving gut health and overall calf health are needed. An increasing number of studies are exploring the microbial composition of the gut, the mucosal immune system, and early dietary interventions to improve the health of dairy calves, revealing possibilities for effectively reducing the susceptibility of calves to enteric infections while promoting growth. Still, comprehensive understanding of the effect of dietary interventions on gut microbiota-one of the key aspects of gut health-is lacking. Such knowledge may provide in-depth understanding of the mechanisms behind functional changes in response to dietary interventions. Understanding of host-microbial interactions with dietary interventions and the role of the gut microbiota during pathogenesis at the site of infection in early life is vital for designing effective tools and techniques to improve calf gut health. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

An SO(10) × SO(10)' model for common origin of neutrino masses, ordinary and dark matter-antimatter asymmetries

Energy Technology Data Exchange (ETDEWEB)

Gu, Pei-Hong, E-mail: peihong.gu@sjtu.edu.cn [Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240 (China)

2014-12-01

We propose an SO(10) × SO(10)' model to simultaneously realize a seesaw for Dirac neutrino masses and a leptogenesis for ordinary and dark matter-antimatter asymmetries. A (16 × 1-bar 6-bar '){sub H} scalar crossing the SO(10) and SO(10)' sectors plays an essential role in this seesaw-leptogenesis scenario. As a result of lepton number conservation, the lightest dark nucleon as the dark matter particle should have a determined mass around 15 GeV to explain the comparable fractions of ordinary and dark matter in the present universe. The (16 × 1-bar 6-bar '){sub H} scalar also mediates a U(1){sub em} × U(1)'{sub em} kinetic mixing after the ordinary and dark left-right symmetry breaking so that we can expect a dark nucleon scattering in direct detection experiments and/or a dark nucleon decay in indirect detection experiments. Furthermore, we can impose a softly broken mirror symmetry to simplify the parameter choice.

Neutrino mixing in SO(10)

International Nuclear Information System (INIS)

Milton, K.; Hama, S.; Nandi, S.; Tanaka, K.

1980-01-01

Neutrino mixing angles were computed in terms of upquark mass ratios in a grand unified field theory based on the gauge group SO(10) supplemented by a discrete symmetry. Only large ν/sub μ/ - ν/sub tau/ mixing were found

Prospects for R-Parity Conserving SUSY searches at the LHC

CERN Document Server

The ATLAS collaboration

2009-01-01

The talk reviews the current strategies to search for generic SUSY models with R-parity conservation in the ATLAS and CMS detectors at the LHC. The discovery reach in early data is presented for different search channels based on missing transverse momentum from undetected neutralinos and multiple jets. The talk will also describe the search for models of gauge-mediated supersymmetry breaking for which the NLSP is a neutralino decaying to a photon and a gravitino. In this scenario, the search strategy exploits the distinct signature of a non-pointing photon. Finally, we present recent work on techniques used to reconstruct the decays of SUSY particles at the LHC in early data, based on the selection of final-state exclusive decay chains.

Flop transitions in cuprate and color superconductors: From SO(5) to SO(10) unification?

Energy Technology Data Exchange (ETDEWEB)

Chandrasekharan, S.; Chudnovsky, V.; Schlittgen, B.; Wiese, U.-J

2001-03-01

The phase diagrams of cuprate superconductors and of QCD at non-zero baryon chemical potential are qualitatively similar. The Neel phase of the cuprates corresponds to the chirally broken phase of QCD, and the high-temperature superconducting phase corresponds to the color superconducting phase. In the SO(5) theory for the cuprates the SO(3){sub s} spin rotational symmetry and the U(1){sub em} gauge symmetry of electromagnetism are dynamically unified. This suggests that the SU(2){sub L} x SU(2){sub R} x U(1){sub B} chiral symmetry of QCD and the SU(3){sub c} color gauge symmetry may get unified to SO(10). Dynamical enhancement of symmetry from SO(2){sub s} x Z(2) to SO(3){sub s} is known to occur in anisotropic antiferromagnets. In these systems the staggered magnetization flops from an easy 3-axis into the 12-plane at a critical value of the external magnetic field. Similarly, the phase transitions in the SO(5) and SO(10) models are flop transitions of a 'superspin'. Despite this fact, a renormalization group flow analysis in 4 -- {epsilon} dimensions indicates that a point with full SO(5) or SO(10) symmetry exists neither in the cuprates nor in QCD.

Flop transitions in cuprate and color superconductors: From SO(5) to SO(10) unification?

International Nuclear Information System (INIS)

Chandrasekharan, S.; Chudnovsky, V.; Schlittgen, B.; Wiese, U.-J.

2001-01-01

The phase diagrams of cuprate superconductors and of QCD at non-zero baryon chemical potential are qualitatively similar. The Neel phase of the cuprates corresponds to the chirally broken phase of QCD, and the high-temperature superconducting phase corresponds to the color superconducting phase. In the SO(5) theory for the cuprates the SO(3) s spin rotational symmetry and the U(1) em gauge symmetry of electromagnetism are dynamically unified. This suggests that the SU(2) L x SU(2) R x U(1) B chiral symmetry of QCD and the SU(3) c color gauge symmetry may get unified to SO(10). Dynamical enhancement of symmetry from SO(2) s x Z(2) to SO(3) s is known to occur in anisotropic antiferromagnets. In these systems the staggered magnetization flops from an easy 3-axis into the 12-plane at a critical value of the external magnetic field. Similarly, the phase transitions in the SO(5) and SO(10) models are flop transitions of a 'superspin'. Despite this fact, a renormalization group flow analysis in 4 -- ε dimensions indicates that a point with full SO(5) or SO(10) symmetry exists neither in the cuprates nor in QCD

SUSY see-saw and NMSO(10)GUT inflation after BICEP2

Indian Academy of Sciences (India)

2016-01-13

Jan 13, 2016 ... Recently, BICEP2, a telescope mounted at the south pole for background imaging of cosmic extragalatic polarization claimed the detection of the signal of primordial gravitational waves. The gravitational waves active during the inflationary epoch produce polarization in cosmic microwave background.

Ok, so who wants to colonise my gut? - Overview of Probiotics in ...

African Journals Online (AJOL)

(6) Be able to interact or to send signals to the immune cells by .... colonization and persistence within, and (8) stimulation of innate immune response (by unknown ... with gut-associated lymphoid tissue (GALT) respond in an unusual.

SO(10) - Grand unification and fermion masses

International Nuclear Information System (INIS)

Oezer, A.D.

2005-01-01

In this work, we study SO(10) grand unification in its full extent by using different explicit matrix representations which exhibit the structure of SO(10) in a very transparent way. Our approach consists mainly of two stages: We derive the explicit expressions of the mass-eigenvalues and mass-eigenstates of the physical gauge bosons from a mass squared-matrix that contains all the information about the mixing parameters among the gauge fields and the phases which are sources for CP violation. In the light of this analysis, we derive the explicit expressions for the interaction Lagrangians of the charged currents, the neutral currents and the charged and colored currents in SO(10). We present explicit expressions of the vector and axial-vector couplings of the two neutral currents in SO(10). We show how the baryon, lepton and baryon minus lepton number violating processes and their explicit CP violating phases are accommodated in the SO(10) theory. The Higgs potential that we use to implement in the Higgs mechanism is constructed in a most general fashion through a careful study of the Higgs fields of SO(10), where we give special emphasis on illustrating the explicit matrix representation of these Higgs fields. The potential part of the Higgs Lagrangian will give us the properties of the minimum of the vacuum, and the kinetic part will give us the mass-squared matrix of the gauge bosons via spontaneous symmetry breakdown. The same Higgs multiplets will be coupled to fermions through a democratic Yukawa matrix. Thereby, we derive explicit expressions for the fermion masses of the third family including Majorana and Dirac masses for neutrinos. We introduce a flavor-eigenbasis for neutrinos and find the mass-eigenstates and mass-eigenvalues of the neutrinos. Explicit expressions for CP violation in the neutrino sector are obtained. In the second stage of our work, we evaluate all the above mentioned quantities. In addition, we present the values of the physical

Two Higgs doublets in SO(10) model

International Nuclear Information System (INIS)

Asatryan, G.M.

1989-01-01

An SO(10) grand unification model is suggested with two light Higgs doublets, whose vacuum expectation values are connected with the SU(2) L xU(1) Y electroweak group breaking. Taking into account the naturality condition associated with absence of flavor changing neutral currents, a certain form of the quark mass matrices. As a result, the proton lifetime in the SO(10) model turns to be strongly restrained

Extraction of the Susy and Higgs parameters

International Nuclear Information System (INIS)

Adam-Bourdarios, Claire

2010-01-01

If supersymmetry is discovered by the next generation of collider experiments, it will be crucial to determine its fundamental high-scale parameters. Three scenarios have been recently investigated by the SFitter collaboration : the case where the LHC 'only' measures a light Higgs like signal, the case where SUSY signal are discovered at the LHC, and the dream scenario, where LHC and ILC measurements can be combined.

Futility of high-precision SO(10) calculations

International Nuclear Information System (INIS)

Dixit, V.V.; Sher, M.

1989-01-01

In grand unified models, there are a large number of scalar bosons with masses of the order of the unification scale. Since the masses could be an order of magnitude or so above or below the vector-boson masses, they will affect the beta functions and thus low-energy predictions; the lack of knowledge of the masses translates into an uncertainty in these predictions. Although the effect is very small for a single scalar field, SO(10) models have hundreds of such fields, leading to very large uncertainties. We analyze this effect in SO(10) models with intermediate scales, and show that all such models have an additional uncertainty which can be as large as 4 orders of magnitude in the proton lifetime and as large as a factor of 0.02 in sin 2 θ w . In models with 210-dimensional representations, the weak mixing angle is uncertain by as much as 0.06. As a result, we argue that precise calculations in SO(10) models with intermediate scales may not be possible

Analytic properties of high energy production amplitudes in N=4 SUSY

International Nuclear Information System (INIS)

Lipatov, L.N.; Hamburg Univ.

2010-08-01

We investigate analytic properties of the six point planar amplitude in N=4 SUSY at the multi-Regge kinematics for final state particles. For inelastic processes the Steinmann relations play an important role because they give a possibility to fix the phase structure of the Regge pole and Mandelstam cut contributions. The analyticity and factorization constraints allow us to reproduce the two-loop correction to the 6- point BDS amplitude in N=4 SUSY obtained earlier in the leading logarithmic approximation with the use of the s-channel unitarity. The cut contribution has the Moebius invariant form in the transverse momentum subspace. The exponentiation hypothesis for the amplitude in the multi-Regge kinematics is also investigated in LLA. (orig.)

Analytic properties of high energy production amplitudes in N=4 SUSY

Energy Technology Data Exchange (ETDEWEB)

Lipatov, L.N. [St. Petersburg Inst. of Nuclear Physics, Gatchina (Russian Federation); Hamburg Univ. (Germany). 1. Inst. fuer Theoretische Physik

2010-08-15

We investigate analytic properties of the six point planar amplitude in N=4 SUSY at the multi-Regge kinematics for final state particles. For inelastic processes the Steinmann relations play an important role because they give a possibility to fix the phase structure of the Regge pole and Mandelstam cut contributions. The analyticity and factorization constraints allow us to reproduce the two-loop correction to the 6- point BDS amplitude in N=4 SUSY obtained earlier in the leading logarithmic approximation with the use of the s-channel unitarity. The cut contribution has the Moebius invariant form in the transverse momentum subspace. The exponentiation hypothesis for the amplitude in the multi-Regge kinematics is also investigated in LLA. (orig.)

Overview of SUSY results from the ATLAS experiment

Directory of Open Access Journals (Sweden)

Federico Brazzale Simone

2014-04-01

Full Text Available The search for Supersymmetric extensions of the Standard Model (SUSY remains a hot topic in high energy phisycs in the light of the discovery of the Higgs boson with mass of 125 GeV. Supersymmetric particles can cancel out the quadratically-divergent loop corrections to the Higgs boson mass and can explain presence of Dark Matter in the Universe. Moreover, SUSY can unify the gauge couplings of the Standard Model at high energy scales. Under certain theoretical assumptions, some of the super-symmetric particles are preferred to be lighter than one TeV and their discovery can thus be accessible at the LHC. The recent results from searches for Supersymmetry with the ATLAS experiment which utilized up to 21 fb−1 of proton-proton collisions at a center of mass energy of 8 TeV are presented. These searches are focused on inclusive production of squarks and gluinos, on production of third generations squarks, and on electroweak production of charginos and neutralinos. Searches for long-lived particles and R-parity violation are also summarized in the document.

Flipped GUT inflation

Energy Technology Data Exchange (ETDEWEB)

Ellis, John [Theoretical Particle Physics and Cosmology Group, Department of Physics, King’s College London, Strand, London WC2R 2LS (United Kingdom); Theory Division, CERN, Route de Meyrin 385, 1217 Meyrin (Switzerland); Gonzalo, Tomás E.; Harz, Julia; Huang, Wei-Chih [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom)

2015-03-23

We analyse the prospects for constructing hybrid models of inflation that provide a dynamical realisation of the apparent closeness between the supersymmetric GUT scale and the possible scale of cosmological inflation. In the first place, we consider models based on the flipped SU(5)×U(1) gauge group, which has no magnetic monopoles. In one model, the inflaton is identified with a sneutrino field, and in the other model it is a gauge singlet. In both cases we find regions of the model parameter spaces that are compatible with the experimental magnitudes of the scalar perturbations, A{sub s}, and the tilt in the scalar perturbation spectrum, n{sub s}, as well as with an indicative upper limit on the tensor-to-scalar perturbation ratio, r. We also discuss embeddings of these models into SO(10), which is broken at a higher scale so that its monopoles are inflated away.

Flipped GUT inflation

Energy Technology Data Exchange (ETDEWEB)

Ellis, John [Theoretical Particle Physics and Cosmology Group, Department of Physics, King' s College London, Strand, London WC2R 2LS (United Kingdom); Gonzalo, Tomás E.; Harz, Julia; Huang, Wei-Chih, E-mail: john.ellis@cern.ch, E-mail: tomas.gonzalo.11@ucl.ac.uk, E-mail: j.harz@ucl.ac.uk, E-mail: wei-chih.huang@ucl.ac.uk [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom)

2015-03-01

We analyse the prospects for constructing hybrid models of inflation that provide a dynamical realisation of the apparent closeness between the supersymmetric GUT scale and the possible scale of cosmological inflation. In the first place, we consider models based on the flipped SU(5)×U(1) gauge group, which has no magnetic monopoles. In one model, the inflaton is identified with a sneutrino field, and in the other model it is a gauge singlet. In both cases we find regions of the model parameter spaces that are compatible with the experimental magnitudes of the scalar perturbations, A{sub s}, and the tilt in the scalar perturbation spectrum, n{sub s}, as well as with an indicative upper limit on the tensor-to-scalar perturbation ratio, r. We also discuss embeddings of these models into SO(10), which is broken at a higher scale so that its monopoles are inflated away.

Flipped GUT Inflation

CERN Document Server

Ellis, John; Harz, Julia; Huang, Wei-Chih

2015-01-01

We analyse the prospects for constructing hybrid models of inflation that provide a dynamical realisation of the apparent closeness between the supersymmetric GUT scale and the possible scale of cosmological inflation. In the first place, we consider models based on the flipped SU(5)$\\times$U(1) gauge group, which has no magnetic monopoles. In one model, the inflaton is identified with a sneutrino field, and in the other model it is a gauge singlet. In both cases we find regions of the model parameter spaces that are compatible with the experimental magnitudes of the scalar perturbations, $A_s$, and the tilt in the scalar perturbation spectrum, $n_s$, as well as with an indicative upper limit on the tensor-to-scalar perturbation ratio, $r$. We also discuss embeddings of these models into SO(10), which is broken at a higher scale so that its monopoles are inflated away.

Searching for vortex solutions in graphene within an N=2 SUSY framework

International Nuclear Information System (INIS)

Abreu, Everton M.C.; Assis, Leonardo P.G. de; Helayel-Neto, Jose Abdalla; Nogueira, Alvaro L.M.A.; Paschoal, Ricardo C.

2011-01-01

Full text: In a recent work, we proposed an N=1-D=3 supersymmetric (SUSY) extension of Jackiw's et al. chiral gauge theory for graphene. As a first approach, we explored the idea that the chiral gauge formulation for Dirac fermions in graphene could be a sector of a wider SUSY theoretical setup, namely, the N=1 π 3 -QED. As a matter of fact, adding a superpotential operator to the N=1 π 3 -QED prescription, properly endowed with the constitutive chiral gauge and discrete symmetries that prevail in Jackiw's proposal, allows for the recognition of the Yukawa-like terms, along with spontaneous symmetry breaking configurations and corresponding non-null mass eigenvalues to the physical degrees of freedom. However, the additional requirement of invariance under a global phase transformation (GPT), meant to be associated to the electric charge, severely constrains the superpotential, leading to the exclusion of the sector that contains Jackiw's operators. As we proceed to investigate how the GP symmetry could be accommodated in a SUSY formulation, in the work of Ref. [E.M.C. Abreu, M.A. De Andrade, L.P.G. de Assis, J.A. Helayel-Neto, A.L.M.A. Nogueira and R.C. Paschoal, N=2-D=3 Supersymmetry and the Electric Charge in Graphene] we assess the straightforward N=1-generalization of Jackiw-Pi's chiral gauge theory, obtained at the cost of adding an extra superfield to the original SUSY-π 3 -QED field content. Moreover, we are able to construct an N=2-D=3 further extension of the chiral gauge theory for electrons in graphene. Such an N=2 SUSY framework provides an algebraic structure rich enough to imply a set of equations that minimizes the energy functional, namely, the well-known Bogomol'nyi equations. In this work, by taking the action of one of the supersymmetry charges to be trivial, we obtain the proper set of Bogomol'nyi equations. We finally impose a vortex-like trial solution, as we wish to discuss the resulting non-perturbative spectrum of the present N=2 setup

Searching for vortex solutions in graphene within an N=2 SUSY framework

Energy Technology Data Exchange (ETDEWEB)

Abreu, Everton M.C. [Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropedica, RJ (Brazil). Dept. de Fisica; Andrade, Marco A. de [Universidade do Estado do Rio de Janeiro (UERJ), Resende, RJ (Brazil); Grupo de Fisica Teorica Jose Leite Lopes (GFT-JLL), Petropolis, RJ (Brazil); Assis, Leonardo P.G. de [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Helayel-Neto, Jose Abdalla [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Grupo de Fisica Teorica Jose Leite Lopes (GFT-JLL), Petropolis, RJ (Brazil); Nogueira, Alvaro L.M.A.; Paschoal, Ricardo C. [Centro Federal de Educacao Tecnologica Celso Suckow da Fonseca (CEFET/RJ), Rio de Janeiro, RJ (Brazil); Grupo de Fisica Teorica Jose Leite Lopes (GFT-JLL), Petropolis, RJ (Brazil)

2011-07-01

Full text: In a recent work, we proposed an N=1-D=3 supersymmetric (SUSY) extension of Jackiw's et al. chiral gauge theory for graphene. As a first approach, we explored the idea that the chiral gauge formulation for Dirac fermions in graphene could be a sector of a wider SUSY theoretical setup, namely, the N=1 {pi}{sub 3}-QED. As a matter of fact, adding a superpotential operator to the N=1 {pi}{sub 3}-QED prescription, properly endowed with the constitutive chiral gauge and discrete symmetries that prevail in Jackiw's proposal, allows for the recognition of the Yukawa-like terms, along with spontaneous symmetry breaking configurations and corresponding non-null mass eigenvalues to the physical degrees of freedom. However, the additional requirement of invariance under a global phase transformation (GPT), meant to be associated to the electric charge, severely constrains the superpotential, leading to the exclusion of the sector that contains Jackiw's operators. As we proceed to investigate how the GP symmetry could be accommodated in a SUSY formulation, in the work of Ref. [E.M.C. Abreu, M.A. De Andrade, L.P.G. de Assis, J.A. Helayel-Neto, A.L.M.A. Nogueira and R.C. Paschoal, N=2-D=3 Supersymmetry and the Electric Charge in Graphene] we assess the straightforward N=1-generalization of Jackiw-Pi's chiral gauge theory, obtained at the cost of adding an extra superfield to the original SUSY-{pi}{sub 3}-QED field content. Moreover, we are able to construct an N=2-D=3 further extension of the chiral gauge theory for electrons in graphene. Such an N=2 SUSY framework provides an algebraic structure rich enough to imply a set of equations that minimizes the energy functional, namely, the well-known Bogomol'nyi equations. In this work, by taking the action of one of the supersymmetry charges to be trivial, we obtain the proper set of Bogomol'nyi equations. We finally impose a vortex-like trial solution, as we wish to discuss the resulting non

Phenomenological analysis of supersymmetric σ-models on coset spaces SO(10)/U(5) and E6/[SO(10)xU(1)

International Nuclear Information System (INIS)

Nyawelo, T.S.

2004-12-01

We discuss some phenomenological aspects of gauged supersymmetric σ-models on homogeneous coset-spaces E 6 /[SO(10)xU(1)] and SO(10)/U(5) which are some of the most interesting for phenomenology. We investigate in detail the vacuum configurations of these models, and study the resulting consequences for supersymmetry breaking and breaking of the internal symmetry. Some supersymmetric minima for both models with gauged full isometry groups E 6 and SO(10) are physically problematic as the Kaehler metric becomes singular ad hence the kinetic terms of the Goldstone boson multiplets vanish. This leads us to introduce recently proposed soft supersymmetry-breaking mass terms which displace the minimum away from the singulax point. A non-singular Kaehler metric breaks the linear subgroup SO(10)xU(1) of the E 6 model spontaneously. The particle spectrum of all these different models is computed. (author)

On the diversity of gauge mediation: footprints of dynamical SUSY breaking

International Nuclear Information System (INIS)

Abel, Steven; Jaeckel, Joerg; Khoze, Valentin V.; Matos, Luis

2009-01-01

Recent progress in realising dynamical supersymmetry breaking allows the construction of simple and calculable models of gauge mediation. We discuss the phenomenology of the particularly minimal case in which the mediation is direct, and show that there are generic new and striking predictions. These include new particles with masses comparable to those of the Standard Model superpartners, associated with the pseudo-Goldstone modes of the dynamical SUSY breaking sector. Consequently there is an unavoidable departure from the MSSM. In addition the gaugino masses are typically significantly lighter than the sfermions, and their mass ratios can be different from the pattern dictated by the gauge couplings in standard (i.e. explicit) gauge mediation. We investigate these features in two distinct realisations of the dynamical SUSY breaking sector.

SUSY searches at $\\sqrt{s}=13$ TeV with two same-sign leptons or three leptons, jets and $E_T^{miss}$ at the ATLAS detector - Background estimation and latest analysis results.

CERN Document Server

Tornambe, Peter; The ATLAS collaboration

2017-01-01

Supersymmetry (SUSY) is one of the most studied theories to extend the Standard Model (SM) beyond the electroweak scale. If R-parity is conserved, SUSY particles are produced in pairs and the lightest supersymmetric particle (LSP), which is typically the lightest neutrino $\\tilde{\\chi}_1^0$, is stable. In many models the LSP can be a suitable candidate for dark matter. This poster presents a search for supersymmetric phenomena in final states with two leptons (electrons or muons) of the same electric charge or three leptons, jets and missing transverse energy. While the same-sign or three leptons signature is present in many SUSY scenarios, SM processes leading to such events have very small cross-sections. Therefore, this analysis benefits from a small SM background in the signal regions leading to a good sensitivity especially in SUSY scenarios with compressed mass spectra or in which the R-parity is not conserved. Except from the prompt production of same-sign lepton pairs or three leptons, the main source...

Interpretation of Higgs and Susy searches in MSUGRA and GMSB Models

International Nuclear Information System (INIS)

Vivie, J.B. de

1999-10-01

HIGGS and SUSY searches performed by the ALEPH Experiment at LEP are interpreted in the framework of two constrained R-parity conserving models: Minimal Supergravity and minimal Gauge Mediated Supersymmetry Breaking. (author)

Albumin infusion after reperfusion prevents gut ischemia-reperfusion-induced gut-associated lymphoid tissue atrophy.

Science.gov (United States)

Ikezawa, Fumie; Fukatsu, Kazuhiko; Moriya, Tomoyuki; Maeshima, Yoshinori; Okamoto, Koichi; Hara, Etsuko; Hiraide, Hoshio; Compher, Charlene W

2006-01-01

Our recent study clarified that gut ischemia-reperfusion (I/R) causes gut-associated lymphoid tissue (GALT) mass atrophy, a possible mechanism for increased morbidity of infectious complications after severe surgical insults. Because albumin administration reportedly reduces hemorrhagic shock-induced lung injury, we hypothesized that albumin treatment prevents GALT atrophy due to gut I/R. Male mice (n = 37) were randomized to albumin, normal saline, and sham groups. All groups underwent jugular vein catheter insertion. The albumin and normal saline groups underwent 75-minute occlusion of the superior mesenteric artery. During gut ischemia, all mice received normal saline infusions at 1.0 mL/h. The albumin group was given 5% bovine serum albumin in normal saline at 1.0 mL/h for 60 minutes after reperfusion, whereas the normal saline group received 0.9% sodium chloride at 1.0 mL/h. The sham group underwent laparotomy only. Mice were killed on day 1 or 7, and the entire small intestine was harvested. GALT lymphocytes were isolated and counted. Their phenotypes (alphabetaTCR, gammadeltaTCR, CD4, CD8, B220) were determined by flow cytometry. On day 1, the gut I/R groups showed significantly lower total lymphocyte and B cell numbers in Peyer's patches and the lamina propria than the sham group. However, the albumin infusion partially but significantly restored these cell numbers. On day 7, there were no significant differences in any of the parameters measured among the 3 groups. Albumin infusion after a gut ischemic insult may maintain gut immunity by preventing GALT atrophy.

SUSY searches in early CMS data

International Nuclear Information System (INIS)

Tricomi, A

2008-01-01

In the first year of data taking at LHC, the CMS experiment expects to collect about 1 fb -1 of data, which make possible the first searches for new phenomena. All such searches require however the measurement of the SM background and a detailed understanding of the detector performance, reconstruction algorithms and triggering. The CMS efforts are hence addressed to designing a realistic analysis plan in preparation to the data taking. In this paper, the CMS perspectives and analysis strategies for Supersymmetry (SUSY) discovery with early data are presented

Gut dysbiosis and detection of "live gut bacteria" in blood of Japanese patients with type 2 diabetes.

Science.gov (United States)

Sato, Junko; Kanazawa, Akio; Ikeda, Fuki; Yoshihara, Tomoaki; Goto, Hiromasa; Abe, Hiroko; Komiya, Koji; Kawaguchi, Minako; Shimizu, Tomoaki; Ogihara, Takeshi; Tamura, Yoshifumi; Sakurai, Yuko; Yamamoto, Risako; Mita, Tomoya; Fujitani, Yoshio; Fukuda, Hiroshi; Nomoto, Koji; Takahashi, Takuya; Asahara, Takashi; Hirose, Takahisa; Nagata, Satoru; Yamashiro, Yuichiro; Watada, Hirotaka

2014-08-01

Mounting evidence indicates that the gut microbiota are an important modifier of obesity and diabetes. However, so far there is no information on gut microbiota and "live gut bacteria" in the systemic circulation of Japanese patients with type 2 diabetes. Using a sensitive reverse transcription-quantitative PCR (RT-qPCR) method, we determined the composition of fecal gut microbiota in 50 Japanese patients with type 2 diabetes and 50 control subjects, and its association with various clinical parameters, including inflammatory markers. We also analyzed the presence of gut bacteria in blood samples. The counts of the Clostridium coccoides group, Atopobium cluster, and Prevotella (obligate anaerobes) were significantly lower (P blood at a significantly higher rate in diabetic patients than in control subjects (28% vs. 4%, P type 2 diabetes as assessed by RT-qPCR. The high rate of gut bacteria in the circulation suggests translocation of bacteria from the gut to the bloodstream. © 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Effective Lagrangians for SUSY QCD with properties seen in perturbation theory

International Nuclear Information System (INIS)

Sharatchandra, H.S.

1984-06-01

We construct effective Lagrangians for supersymmetric QCD which properly incorporate the relevant Ward identities and possess features encountered in perturbation theory. This shows that the unusual scenarios, proposed for SUSY QCD, are not necessary. (author)

Neutrino mass from M theory SO(10)

International Nuclear Information System (INIS)

Acharya, Bobby S.; Bożek, Krzysztof; Romão, Miguel Crispim; King, Stephen F.; Pongkitivanichkul, Chakrit

2016-01-01

We study the origin of neutrino mass from SO(10) arising from M Theory compactified on a G_2-manifold. This is linked to the problem of the breaking of the extra U(1) gauge group, in the SU(5)×U(1) subgroup of SO(10), which we show can achieved via a (generalised) Kolda-Martin mechanism. The resulting neutrino masses arise from a combination of the seesaw mechanism and induced R-parity breaking contributions. The rather complicated neutrino mass matrix is analysed for one neutrino family and it is shown how phenomenologically acceptable neutrino masses can emerge.

Neutrino mass from M theory SO(10)

Energy Technology Data Exchange (ETDEWEB)

Acharya, Bobby S. [Department of Physics, King’s College,WC2R 2LS, London (United Kingdom); International Centre for Theoretical Physics,I-34151 Trieste (Italy); Bożek, Krzysztof [Department of Physics, King’s College,WC2R 2LS, London (United Kingdom); Romão, Miguel Crispim; King, Stephen F. [School of Physics and Astronomy, University of Southampton,SO17 1BJ, Southampton (United Kingdom); Pongkitivanichkul, Chakrit [Department of Physics, King’s College,WC2R 2LS, London (United Kingdom)

2016-11-29

We study the origin of neutrino mass from SO(10) arising from M Theory compactified on a G{sub 2}-manifold. This is linked to the problem of the breaking of the extra U(1) gauge group, in the SU(5)×U(1) subgroup of SO(10), which we show can achieved via a (generalised) Kolda-Martin mechanism. The resulting neutrino masses arise from a combination of the seesaw mechanism and induced R-parity breaking contributions. The rather complicated neutrino mass matrix is analysed for one neutrino family and it is shown how phenomenologically acceptable neutrino masses can emerge.

Probing the Higgs sector of high-scale SUSY-breaking models at the Tevatron

Energy Technology Data Exchange (ETDEWEB)

Carena, Marcela [Fermi National Accelerator Laboratory, Batavia, IL (United States); Chicago Univ., Chicago, IL (United States). Enrico Fermi Inst.; Draper, Patrick [Chicago Univ., Chicago, IL (United States). Enrico Fermi Inst.; Heinemeyer, Sven [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain); Liu, Tao [Chicago Univ., Chicago, IL (United States). Enrico Fermi Inst.; California Univ., Santa Barbara, CA (United States). Dept. of Physics; Wagner, Carlos E.M. [Chicago Univ., Chicago, IL (United States). Enrico Fermi Inst.; Argonne National Laboratory, Argonne, IL (United States). HEP Div.; Chicago Univ., Chicago, IL (United States). KICP and Dept. of Physics; Weiglein, Georg [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

2010-12-15

A canonical signature of the Minimal Supersymmetric Standard Model (MSSM) is the presence of a neutral Higgs boson with mass bounded from above by about 135 GeV and Standard Model (SM)-like couplings to the electroweak gauge bosons. In this note we investigate the reach of the Tevatron collider for the MSSM Higgs sector parameter space associated with a variety of high-scale minimal models of supersymmetry (SUSY)-breaking, including the Constrained MSSM (CMSSM), minimal Gauge Mediated SUSY-breaking (mGMSB), and minimal Anomaly Mediated SUSY-breaking (mAMSB). We find that the Tevatron can provide strong constraints on these models via Higgs boson searches. Considering a simple projection for the efficiency improvements in the Tevatron analyses, we find that with an integrated luminosity of 16 fb{sup -1} per detector and an efficiency improvement of 20% compared to the present situation, these models could be probed essentially over their entire ranges of validity. With 40% analysis improvements and 16 fb{sup -1}, our projection shows that evidence at the 3{sigma} level for the light Higgs boson could be expected in extended regions of parameter space. (orig.)

Probing the Higgs sector of high-scale SUSY-breaking models at the Tevatron

International Nuclear Information System (INIS)

Carena, Marcela; Liu, Tao

2010-12-01

A canonical signature of the Minimal Supersymmetric Standard Model (MSSM) is the presence of a neutral Higgs boson with mass bounded from above by about 135 GeV and Standard Model (SM)-like couplings to the electroweak gauge bosons. In this note we investigate the reach of the Tevatron collider for the MSSM Higgs sector parameter space associated with a variety of high-scale minimal models of supersymmetry (SUSY)-breaking, including the Constrained MSSM (CMSSM), minimal Gauge Mediated SUSY-breaking (mGMSB), and minimal Anomaly Mediated SUSY-breaking (mAMSB). We find that the Tevatron can provide strong constraints on these models via Higgs boson searches. Considering a simple projection for the efficiency improvements in the Tevatron analyses, we find that with an integrated luminosity of 16 fb -1 per detector and an efficiency improvement of 20% compared to the present situation, these models could be probed essentially over their entire ranges of validity. With 40% analysis improvements and 16 fb -1 , our projection shows that evidence at the 3σ level for the light Higgs boson could be expected in extended regions of parameter space. (orig.)

Determination of excited states of quantum systems by finite difference time domain method (FDTD) with supersymmetric quantum mechanics (SUSY-QM)

Energy Technology Data Exchange (ETDEWEB)

Sudiarta, I. Wayan; Angraini, Lily Maysari, E-mail: lilyangraini@unram.ac.id [Physics Study Program, University of Mataram, Jln. Majapahit 62 Mataram, NTB (Indonesia)

2016-04-19

We have applied the finite difference time domain (FDTD) method with the supersymmetric quantum mechanics (SUSY-QM) procedure to determine excited energies of one dimensional quantum systems. The theoretical basis of FDTD, SUSY-QM, a numerical algorithm and an illustrative example for a particle in a one dimensional square-well potential were given in this paper. It was shown that the numerical results were in excellent agreement with theoretical results. Numerical errors produced by the SUSY-QM procedure was due to errors in estimations of superpotentials and supersymmetric partner potentials.

Non-simplified SUSY. {tau}-coannihilation at LHC and ILC

Energy Technology Data Exchange (ETDEWEB)

Berggren, M.; Cakir, A.; Krueger, D.; List, J.; Lobanov, A.; Melzer-Pellmann, I.A.

2013-07-15

Simplified models have become a widely used and important tool to cover the more diverse phenomenology beyond constrained SUSY models. However, they come with a substantial number of caveats themselves, and great care needs to be taken when drawing conclusions from limits based on the simplified approach. To illustrate this issue with a concrete example, we examine the applicability of simplified model results to a series of full SUSY model points which all feature a small {tau} -LSP mass difference, and are compatible with electroweak and flavor precision observables as well as current LHC results. Various channels have been studied using the Snowmass Combined LHC detector implementation in the Delphes simulation package, as well as the Letter of Intent or Technical Design Report simulations of the ILD detector concept at the ILC. We investigated both the LHC and ILC capabilities for discovery, separation and identification of all parts of the spectrum. While parts of the spectrum would be discovered at the LHC, there is substantial room for further discoveries and property determination at the ILC.

Low-scale SUSY breaking and the (s)goldstino physics

CERN Document Server

Antoniadis, I.

2013-01-01

For a 4D N=1 supersymmetric model with a low SUSY breaking scale (f) and general Kahler potential K(Phi^i,Phi_j^*) and superpotential W(Phi^i) we study, in an effective theory approach, the relation of the goldstino superfield to the (Ferrara-Zumino) superconformal symmetry breaking chiral superfield X. In the presence of more sources of supersymmetry breaking, we verify the conjecture that the goldstino superfield is the (infrared) limit of X for zero-momentum and Lambda->\\infty. (Lambda is the effective cut-off scale). We then study the constraint X^2=0, which in the one-field case is known to decouple a massive sgoldstino and thus provide an effective superfield description of the Akulov-Volkov action for the goldstino. In the presence of additional fields that contribute to SUSY breaking we identify conditions for which X^2=0 remains valid, in the effective theory below a large but finite sgoldstino mass. The conditions ensure that the effective expansion (in 1/Lambda) of the initial Lagrangian is not in ...

SUSY-hierarchy of one-dimensional reflectionless potentials

International Nuclear Information System (INIS)

Maydanyuk, Sergei P.

2005-01-01

A class of one-dimensional reflectionless potentials is studied. It is found that all possible types of the reflectionless potentials can be combined into one SUSY-hierarchy with a constant potential. An approach for determination of a general form of the reflectionless potential on the basis of construction of such a hierarchy by the recurrent method is proposed. A general integral form of interdependence between superpotentials with neighboring numbers of this hierarchy, opening a possibility to find new reflectionless potentials, is found and has a simple analytical view. It is supposed that any possible type of the reflectionless potential can be expressed through finite number of elementary functions (unlike some presentations of the reflectionless potentials, which are constructed on the basis of soliton solutions or are shape invariant in one or many steps with involving scaling of parameters, and are expressed through series). An analysis of absolute transparency existence for the potential which has the inverse power dependence on space coordinate (and here tunneling is possible), i.e., which has the form V (x) = ± α/ vertical bar x-x 0 vertical bar n (where α and x 0 are constants, n is natural number), is fulfilled. It is shown that such a potential can be reflectionless at n = 2 only. A SUSY-hierarchy of the inverse power reflectionless potentials is constructed. Isospectral expansions of this hierarchy are analyzed

Discrete symmetries in the heterotic-string landscape

International Nuclear Information System (INIS)

Athanasopoulos, P

2015-01-01

We describe a new type of discrete symmetry that relates heterotic-string models. It is based on the spectral flow operator which normally acts within a general N = (2, 2) model and we use this operator to construct a map between N = (2, 0) models. The landscape of N = (2, 0) models is of particular interest among all heterotic-string models for two important reasons: Firstly, N =1 spacetime SUSY requires (2, 0) superconformal invariance and secondly, models with the well motivated by the Standard Model SO(10) unification structure are of this type. This idea was inspired by a new discrete symmetry in the space of fermionic ℤ 2 × ℤ 2 heterotic-string models that exchanges the spinors and vectors of the SO(10) GUT group, dubbed spinor-vector duality. We will describe how to generalize this to arbitrary internal rational Conformal Field Theories. (paper)

Discrete symmetries in the heterotic-string landscape

Science.gov (United States)

Athanasopoulos, P.

2015-07-01

We describe a new type of discrete symmetry that relates heterotic-string models. It is based on the spectral flow operator which normally acts within a general N = (2, 2) model and we use this operator to construct a map between N = (2, 0) models. The landscape of N = (2, 0) models is of particular interest among all heterotic-string models for two important reasons: Firstly, N =1 spacetime SUSY requires (2, 0) superconformal invariance and secondly, models with the well motivated by the Standard Model SO(10) unification structure are of this type. This idea was inspired by a new discrete symmetry in the space of fermionic ℤ2 × ℤ2 heterotic-string models that exchanges the spinors and vectors of the SO(10) GUT group, dubbed spinor-vector duality. We will describe how to generalize this to arbitrary internal rational Conformal Field Theories.

Radiative natural SUSY spectrum from deflected AMSB scenario with messenger-matter interactions

Energy Technology Data Exchange (ETDEWEB)

Wang, Fei [School of Physics, Zhengzhou University,Zhengzhou 450000 (China); State Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100080 (China); Yang, Jin Min [State Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100080 (China); Department of Physics, Tohoku University,Sendai 980-8578 (Japan); Zhang, Yang [State Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100080 (China)

2016-04-29

A radiative natural SUSY spectrum are proposed in the deflected anomaly mediation scenario with general messenger-matter interactions. Due to the contributions from the new interactions, positive slepton masses as well as a large |A{sub t}| term can naturally be obtained with either sign of deflection parameter and few messenger species (thus avoid the possible Landau pole problem). In this scenario, in contrast to the ordinary (radiative) natural SUSY scenario with under-abundance of dark matter (DM), the DM can be the mixed bino-higgsino and have the right relic density. The 125 GeV Higgs mass can also be easily obtained in our scenario. The majority of low EW fine tuning points can be covered by the XENON-1T direct detection experiments.

Mandelstam cuts and light-like Wilson loops in N=4 SUSY

Energy Technology Data Exchange (ETDEWEB)

Lipatov, L.N. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; St. Petersburg Inst. of Nuclear Physics, Gatchina (Russian Federation); Prygarin, A. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

2010-08-15

We perform an analytic continuation of the two-loop remainder function for the six-point planar MHV amplitude in N=4 SUSY, found by Goncharov, Spradlin, Vergu and Volovich from the light-like Wilson loop representation. The remainder function is continued into a physical region, where all but two energy invariants are negative. It turns out to be pure imaginary in the multi-Regge kinematics, which is in an agreement with the predictions based on the Steinmann relations for the Regge poles and Mandelstam cut contributions. The leading term reproduces correctly the expression calculated by one of the authors in the BFKL approach, while the subleading term presents a result, that was not yet found with the use of the unitarity techniques. This supports the applicability of the Wilson loop approach to the planar MHV amplitudes in N=4 SUSY. (orig.)

Mandelstam cuts and light-like Wilson loops in N=4 SUSY

International Nuclear Information System (INIS)

Lipatov, L.N.; Prygarin, A.

2010-08-01

We perform an analytic continuation of the two-loop remainder function for the six-point planar MHV amplitude in N=4 SUSY, found by Goncharov, Spradlin, Vergu and Volovich from the light-like Wilson loop representation. The remainder function is continued into a physical region, where all but two energy invariants are negative. It turns out to be pure imaginary in the multi-Regge kinematics, which is in an agreement with the predictions based on the Steinmann relations for the Regge poles and Mandelstam cut contributions. The leading term reproduces correctly the expression calculated by one of the authors in the BFKL approach, while the subleading term presents a result, that was not yet found with the use of the unitarity techniques. This supports the applicability of the Wilson loop approach to the planar MHV amplitudes in N=4 SUSY. (orig.)

Leptogenesis as an origin of hot dark matter and baryon asymmetry in the E6 inspired SUSY models

Science.gov (United States)

Nevzorov, R.

2018-04-01

We explore leptogenesis within the E6 inspired U (1) extension of the MSSM in which exact custodial symmetry forbids tree-level flavour-changing transitions and the most dangerous baryon and lepton number violating operators. This supersymmetric (SUSY) model involves extra exotic matter beyond the MSSM. In the simplest phenomenologically viable scenarios the lightest exotic fermions are neutral and stable. These states should be substantially lighter than 1eV forming hot dark matter in the Universe. The low-energy effective Lagrangian of the SUSY model under consideration possesses an approximate global U(1)E symmetry associated with the exotic states. The U(1)E symmetry is explicitly broken because of the interactions between the right-handed neutrino superfields and exotic matter supermultiplets. As a consequence the decays of the lightest right-handed neutrino/sneutrino give rise to both U(1)E and U(1) B - L asymmetries. When all right-handed neutrino/sneutrino are relatively light ∼106-107GeV the appropriate amount of the baryon asymmetry can be induced via these decays if the Yukawa couplings of the lightest right-handed neutrino superfields to the exotic matter supermultiplets vary between ∼10-4-10-3.

Gauge hierarchy in an SO(10) supersymmetric grand unified model

International Nuclear Information System (INIS)

Zhiyong, Z.

1982-01-01

An SO(10) supersymmetric grand unified model is constructed in which the gauge hierarchy problem may be solved. Using Higgs superfields belonging to the SO(10) representations 16, 10 and 54, it is found that if SO(10) is broken down to SU(3)sub(c)xSU(2)sub(L)xU(1) via SO(6)xSO(4)approximately equal to SU(4)sub(c)xSU(2)sub(L)xSU(2)sub(R) at unification mass scales without supersymmetry breaking, the gauge hierarchy puzzle might be carried away. It is also shown that the colour-triplet Higgs, which mediates proton decay, is superheavy by an incredibly accurate, but 'natural' adjustment of parameters in the potential. (author)

LEP constraints on grand unified theories

International Nuclear Information System (INIS)

Sarkar, Utpal

1993-01-01

Recent developments on grand unified theories (GUTs) in the context of the LEP measurements of the coupling constants are reviewed. The three coupling constants at the electroweak scale have been measured at LEP quite precisely. One can allow these couplings to evolve with energy following the renormalization group equations for the various groups and find out whether all the coupling constants meet at any energy. It was pointed out that the minimal SU(5) grand unified theory fails to satisfy this test. However, various extensions of the theory are still allowed. These extensions include (i) supersymmetric SU(5) GUT, with some arbitrariness in the susy breaking scale arising from the threshold corrections, (ii) non-susy SU(5) GUTs with additional fermions as well as Higgs multiplets, which has masses of the order of TeV, and (iii) non-renormalizable effect of gravity with a fine tuned relation among the coupling constants at the unification energy. The LEP results also constrain GUTs with an intermediate symmetry breaking scale. By adjusting the intermediate symmetry breaking scale, one usually can have unification, but these theories get constrained. For example, the left-right symmetric theories coming from GUTs can be broken only at energies higher than about ∼10 10 GeV. This implies that if right handed gauge bosons are found at energies lower than this scale, then that will rule out the possibility of grand unification. Another recent interesting development on the subject, namely, low energy unification, is discussed in this context. All the coupling constants are unified at energies of the order of ∼10 8 GeV when they are embedded in an SU(15)GUT, with some particular symmetry breaking pattern. But even in this case the results of the intermediate symmetry breaking scale remain unchanged. (author). 16 refs., 3 figs

Higgs scalar in the grand desert with observable proton lifetime in SU(5) and small neutrino masses in SO(10)

International Nuclear Information System (INIS)

Kynshi, M.L.; Parida, M.K.

1993-01-01

We find that the presence of a real scalar in the grand desert transforming as ζ(3,0,8) under SU(2) L xU(1) Y xSU(3) C ensures the agreement of the GUT predictions with the data from CERN LEP and proton lifetime (τ p ). The mass of ζ is predicted to be close to the Peccei-Quinn symmetry-breaking scale. The computation of the threshold effects in SU(5) with Higgs representations 24, 5, and 75 shows that the maximum allowed τ p for reasonable superheavy Higgs boson masses is accessible to experimental tests at low energies. The additional predictions in SO(10) are small neutrino masses compatible with solutions to the solar-neutrino problem and the dark matter of the Universe

Benchmark models, planes lines and points for future SUSY searches at the LHC

International Nuclear Information System (INIS)

AbdusSalam, S.S.; Allanach, B.C.; Dreiner, H.K.

2012-03-01

We define benchmark models for SUSY searches at the LHC, including the CMSSM, NUHM, mGMSB, mAMSB, MM-AMSB and p19MSSM, as well as models with R-parity violation and the NMSSM. Within the parameter spaces of these models, we propose benchmark subspaces, including planes, lines and points along them. The planes may be useful for presenting results of the experimental searches in different SUSY scenarios, while the specific benchmark points may serve for more detailed detector performance tests and comparisons. We also describe algorithms for defining suitable benchmark points along the proposed lines in the parameter spaces, and we define a few benchmark points motivated by recent fits to existing experimental data.

Benchmark models, planes lines and points for future SUSY searches at the LHC

Energy Technology Data Exchange (ETDEWEB)

AbdusSalam, S.S. [The Abdus Salam International Centre for Theoretical Physics, Trieste (Italy); Allanach, B.C. [Cambridge Univ. (United Kingdom). Dept. of Applied Mathematics and Theoretical Physics; Dreiner, H.K. [Bonn Univ. (DE). Bethe Center for Theoretical Physics and Physikalisches Inst.] (and others)

2012-03-15

We define benchmark models for SUSY searches at the LHC, including the CMSSM, NUHM, mGMSB, mAMSB, MM-AMSB and p19MSSM, as well as models with R-parity violation and the NMSSM. Within the parameter spaces of these models, we propose benchmark subspaces, including planes, lines and points along them. The planes may be useful for presenting results of the experimental searches in different SUSY scenarios, while the specific benchmark points may serve for more detailed detector performance tests and comparisons. We also describe algorithms for defining suitable benchmark points along the proposed lines in the parameter spaces, and we define a few benchmark points motivated by recent fits to existing experimental data.

Benchmark Models, Planes, Lines and Points for Future SUSY Searches at the LHC

CERN Document Server

AbdusSalam, S S; Dreiner, H K; Ellis, J; Ellwanger, U; Gunion, J; Heinemeyer, S; Krämer, M; Mangano, M L; Olive, K A; Rogerson, S; Roszkowski, L; Schlaffer, M; Weiglein, G

2011-01-01

We define benchmark models for SUSY searches at the LHC, including the CMSSM, NUHM, mGMSB, mAMSB, MM-AMSB and p19MSSM, as well as models with R-parity violation and the NMSSM. Within the parameter spaces of these models, we propose benchmark subspaces, including planes, lines and points along them. The planes may be useful for presenting results of the experimental searches in different SUSY scenarios, while the specific benchmark points may serve for more detailed detector performance tests and comparisons. We also describe algorithms for defining suitable benchmark points along the proposed lines in the parameter spaces, and we define a few benchmark points motivated by recent fits to existing experimental data.

Constraints on GUTS with Coleman-Weinberg symmetry breaking

International Nuclear Information System (INIS)

Sher, M.A.

1981-01-01

A popular assumption introduced by Coleman and Weinberg is that the elementary Higgs scalars of a gauge theory are massless at the tree level; the symmetry breakdown is then entirely due to quantum radiative corrections. In grand unified theories (GUTS), this assumption becomes particularly attractive. Many GUTS have intermediate mass scales [scales of symmetry breaking between baryon number generation and SU(2) x U(1) breaking], and it is attractive to apply the Coleman-Weinberg assumption to all stages of symmetry breaking after baryon number generation. In this paper, it is shown that most such GUTS are phenomenologically unacceptable. The reason is that as the universe cools, at each scale of symmetry breaking there will be a phase transition; if the symmetry is broken a la Coleman-Weinberg, this transition is strongly first order and thus generates entropy, decreasing the previously generated baryon number to entropy ratio by a large, and perhaps unacceptable amount. The entropy generated in a general intermediate mass scale transition is calculated, and the severe constraints that any Coleman-Weinberg-type GUT with intermediate mass scales must satisfy (in order to avoid excessive entropy generation) are found. Turning to specific models, it is shown that all intermediate mass scale transitions associated with SO(10) do not satisfy these constraints; the Coleman-Weinberg form of these transitions is inconsistent with cosmological observations and is thus phenomenologically unacceptable. (orig.)

Search for compressed SUSY scenarios with the ATLAS detector

CERN Document Server

Maurer, Julien; The ATLAS collaboration

2017-01-01

Scenarios where multiple SUSY states are nearly degenerate in mass produce soft decay products, and they represent an experimental challenge for ATLAS. This talk presents recent results of analyses explicitly targeting such “compressed” scenarios with a variety of experimental techniques. All results make use of proton-proton collisions collected at a centre of mass of 13 TeV with the ATLAS detector.

A human gut phage catalog correlates the gut phageome with type 2 diabetes.

Science.gov (United States)

Ma, Yingfei; You, Xiaoyan; Mai, Guoqin; Tokuyasu, Taku; Liu, Chenli

2018-02-01

Substantial efforts have been made to link the gut bacterial community to many complex human diseases. Nevertheless, the gut phages are often neglected. In this study, we used multiple bioinformatic methods to catalog gut phages from whole-community metagenomic sequencing data of fecal samples collected from both type II diabetes (T2D) patients (n = 71) and normal Chinese adults (n = 74). The definition of phage operational taxonomic units (pOTUs) and identification of large phage scaffolds (n = 2567, ≥ 10 k) revealed a comprehensive human gut phageome with a substantial number of novel sequences encoding genes that were unrelated to those in known phages. Interestingly, we observed a significant increase in the number of gut phages in the T2D group and, in particular, identified 7 pOTUs specific to T2D. This finding was further validated in an independent dataset of 116 T2D and 109 control samples. Co-occurrence/exclusion analysis of the bacterial genera and pOTUs identified a complex core interaction between bacteria and phages in the human gut ecosystem, suggesting that the significant alterations of the gut phageome cannot be explained simply by co-variation with the altered bacterial hosts. Alterations in the gut bacterial community have been linked to the chronic disease T2D, but the role of gut phages therein is not well understood. This is the first study to identify a T2D-specific gut phageome, indicating the existence of other mechanisms that might govern the gut phageome in T2D patients. These findings suggest the importance of the phageome in T2D risk, which warrants further investigation.

Functional Comparison of Bacteria from the Human Gut and Closely Related Non-Gut Bacteria Reveals the Importance of Conjugation and a Paucity of Motility and Chemotaxis Functions in the Gut Environment.

Science.gov (United States)

Dobrijevic, Dragana; Abraham, Anne-Laure; Jamet, Alexandre; Maguin, Emmanuelle; van de Guchte, Maarten

2016-01-01

The human GI tract is a complex and still poorly understood environment, inhabited by one of the densest microbial communities on earth. The gut microbiota is shaped by millennia of evolution to co-exist with the host in commensal or symbiotic relationships. Members of the gut microbiota perform specific molecular functions important in the human gut environment. This can be illustrated by the presence of a highly expanded repertoire of proteins involved in carbohydrate metabolism, in phase with the large diversity of polysaccharides originating from the diet or from the host itself that can be encountered in this environment. In order to identify other bacterial functions that are important in the human gut environment, we investigated the distribution of functional groups of proteins in a group of human gut bacteria and their close non-gut relatives. Complementary to earlier global comparisons between different ecosystems, this approach should allow a closer focus on a group of functions directly related to the gut environment while avoiding functions related to taxonomically divergent microbiota composition, which may or may not be relevant for gut homeostasis. We identified several functions that are overrepresented in the human gut bacteria which had not been recognized in a global approach. The observed under-representation of certain other functions may be equally important for gut homeostasis. Together, these analyses provide us with new information about this environment so critical to our health and well-being.

Functional Comparison of Bacteria from the Human Gut and Closely Related Non-Gut Bacteria Reveals the Importance of Conjugation and a Paucity of Motility and Chemotaxis Functions in the Gut Environment.

Directory of Open Access Journals (Sweden)

Dragana Dobrijevic

Full Text Available The human GI tract is a complex and still poorly understood environment, inhabited by one of the densest microbial communities on earth. The gut microbiota is shaped by millennia of evolution to co-exist with the host in commensal or symbiotic relationships. Members of the gut microbiota perform specific molecular functions important in the human gut environment. This can be illustrated by the presence of a highly expanded repertoire of proteins involved in carbohydrate metabolism, in phase with the large diversity of polysaccharides originating from the diet or from the host itself that can be encountered in this environment. In order to identify other bacterial functions that are important in the human gut environment, we investigated the distribution of functional groups of proteins in a group of human gut bacteria and their close non-gut relatives. Complementary to earlier global comparisons between different ecosystems, this approach should allow a closer focus on a group of functions directly related to the gut environment while avoiding functions related to taxonomically divergent microbiota composition, which may or may not be relevant for gut homeostasis. We identified several functions that are overrepresented in the human gut bacteria which had not been recognized in a global approach. The observed under-representation of certain other functions may be equally important for gut homeostasis. Together, these analyses provide us with new information about this environment so critical to our health and well-being.

Interplay of LFV and slepton mass splittings at the LHC as a probe of the SUSY seesaw

CERN Document Server

Abada, A; Romao, J C; Teixeira, A M

2010-01-01

We study the impact of a type-I SUSY seesaw concerning lepton flavour violation (LFV) both at low-energies and at the LHC. The study of the di-lepton invariant mass distribution at the LHC allows to reconstruct some of the masses of the different sparticles involved in a decay chain. In particular, the combination with other observables renders feasible the reconstruction of the masses of the intermediate sleptons involved in $ \\chi_2^0\\to \\tilde \\ell \\,\\ell \\to \\ell \\,\\ell\\,\\chi_1^0$ decays. Slepton mass splittings can be either interpreted as a signal of non-universality in the SUSY soft breaking-terms (signalling a deviation from constrained scenarios as the cMSSM) or as being due to the violation of lepton flavour. In the latter case, in addition to these high-energy processes, one expects further low-energy manifestations of LFV such as radiative and three-body lepton decays. Under the assumption of a type-I seesaw as the source of neutrino masses and mixings, all these LFV observables are related. Worki...

Precision LEP data, supersymmetric GUTs and string unification

International Nuclear Information System (INIS)

Ellis, J.; Kelley, S.; Nanopoulos, D.V.; Houston Area Research Center

1990-01-01

The precision of sin 2 θ w MS (m Z ) extracted from LEP data (0.233±0.001) confirms the prediction of minimal supersymmetric GUTs (0.235±0.004) within the errors of about 2%. Moreover, supersymmetric GUTs with three generations and a heavy top quark also predict m b =5.2±0.3 GeV in perfect agreement with potential model estimates (5.0±0.2 GeV). String unification would require that the effective grand unification scale m GUT be no larger than the effective string unification scale m SU , which is indeed consistent with the LEP data, which indicate m GUT ≅ 2x10 16 GeV in a minimal supersymmetric GUT, compared with the theoretical estimate m SU ≅ 10 17 GeV. Specific choices of the string model moduli could enforce m GUT =m SU even in minimal supersymmetric GUTs, whilst non-minimal supersymmetric GUTs can reconcile the successful predictions of sin 2 θ w with m GUT = m SU for generic values of the moduli, but tend to have m b too large. (orig.)

Multislice ct in gut related pathologies

International Nuclear Information System (INIS)

Nadeem, A.; Shaukat, A.; Ahmad, M.W.; Amin, Y.

2007-01-01

The objective of this study is to evaluate the effectiveness of Multislice CT in Gut related pathologies. 50 consecutive patients, referred from surgical and medical departments, with gut pathology suspicion were scanned in this respect on Toshiba MSCT 4 slice Aquilion. Patients were. 100 ml iodinated non ionic IV contrast was given. Preferably water was used as oral contrast and oral iodinated contrast was used only in selective cases. As a result, 33 patients showed positive response and 17 were normal; 23 were females and 10 were males. We found following pathologies Acute Appendicitis 10, Diverticulitis 02, Inflammatory Bowel Disease 03, Small Bowel Obstruction 04, Malignant Gut masses 08, Omental Implants 05, Perforation (Duodenal) 01. It is thus concluded that MDCT has a definite role in gut pathologies especially when the ultrasound is negative. (author)

Natural gauge hierarchy in SO(10)

International Nuclear Information System (INIS)

Babu, K.S.; Barr, S.M.

1994-01-01

It is shown that a natural gauge hierarchy and doublet-triplet splitting can be achieved in SO(10) using the Dimopoulos-Wilczek mechanism. Artificial cancellations (fine-tuning) and arbitrary forms of the superpotential are avoided, the superpotential being the most general compatible with a symmetry. It is shown by example that the Dimopoulos-Wilczek mechanism can be protected against the effects of higher-dimension operators possibly induced by Planck-scale physics. Natural implementation of the mechanisms leads to an automatic Peccei-Quinn symmetry. The same local symmetries that would protect the gauge hierarchy against Planck-scale effects tend to protect the axion also. How realistic quark and lepton masses might arise in this framework is discussed. It is shown how the theory may remain perturbative up to the Planck scale. It is also argued that ''weak suppression'' of proton decay can be implemented more economically than can ''strong suppression,'' offering some grounds to hope [in the context of SO(10)] that proton decay could be seen at SuperKamiokande

Search for compressed SUSY scenarios with the ATLAS detector

CERN Document Server

Maurer, Julien; The ATLAS collaboration

2017-01-01

Scenarios where multiple SUSY states are nearly degenerate in mass produce soft decay products, and they represent an experimental challenge for ATLAS. This contribution presented recent results of analyses explicitly targeting such ``compressed'' scenarios with a variety of experimental techniques. All results made use of proton-proton collisions collected at a centre-of-mass energy of 13 TeV with the ATLAS detector at the LHC.

SUSY Flat Directions - to get a VEV or not?

International Nuclear Information System (INIS)

Basboell, Anders

2010-01-01

We investigate the potential of SUSY flat directions (FDs). Large FD vacuum expectation values (VEVs) can delay thermalisation and solve the gravitino problem--if FDs decay perturbatively. This depends on how many and which directions get the VEVs. Recently the decay of the FDs have been studied with the VEVs as input. Here we look at how the VEVs come about--statistically and analytically.

Diminution of the gut resistome after a gut microbiota-targeted dietary intervention in obese children.

Science.gov (United States)

Wu, Guojun; Zhang, Chenhong; Wang, Jing; Zhang, Feng; Wang, Ruirui; Shen, Jian; Wang, Linghua; Pang, Xiaoyan; Zhang, Xiaojun; Zhao, Liping; Zhang, Menghui

2016-04-05

The gut microbiome represents an important reservoir of antibiotic resistance genes (ARGs). Effective methods are urgently needed for managing the gut resistome to fight against the antibiotic resistance threat. In this study, we show that a gut microbiota-targeted dietary intervention, which shifts the dominant fermentation of gut bacteria from protein to carbohydrate, significantly diminished the gut resistome and alleviated metabolic syndrome in obese children. Of the non-redundant metagenomic gene catalog of ~2 × 10(6) microbial genes, 399 ARGs were identified in 131 gene types and conferred resistance to 47 antibiotics. Both the richness and diversity of the gut resistome were significantly reduced after the intervention. A total of 201 of the 399 ARGs were carried in 120 co-abundance gene groups (CAGs) directly binned from the gene catalog across both pre-and post-intervention samples. The intervention significantly reduced several CAGs in Klebsiella, Enterobacter and Escherichia, which were the major hubs for multiple resistance gene types. Thus, dietary intervention may become a potentially effective method for diminishing the gut resistome.

Hilkka Punainen & Susi : mediakasvatuksellisen iPad-kirjan suunnittelu

OpenAIRE

Kontiola, Sanna

2012-01-01

Opinnäytetyön tavoitteena oli tehdä mediakasvatuksellinen iPad-kirja "Hilkka Punainen & Susi", jota voitaisiin käyttää kirjastoissa, kouluissa ja kotona mediakasvatuksen apuvälineenä. Mediakasvatus ei ole ainoastaan medioiden ja välineiden käyttötaidon opettelua, vaan myös sellaisten turvataitojen opettelua, joiden tarkoituksena on parantaa lasten taitoja selviytyä uhkaavissa tilanteissa ja ohjata heitä turvautumaan luotettaviin aikuisiin. Teoksella on useita mediakasvatuksellisia tasoja. Teo...

No-scale SUGRA SO(10) Inflation

Indian Academy of Sciences (India)

Ila Garg

2017-10-09

Oct 9, 2017 ... In the present work, we study inflation in a renormal- izable grand unified theory based on the SO(10) gauge group with no-scale SUGRA. In this paper ..... This work was done in collaboration with Subhendra. Mohanty and is based on paper [29]. References. [1] A A Starobinsky, Phys. Lett. B 91, 99 (1980).

Neutrino masses and the unification of the SO(10) families

International Nuclear Information System (INIS)

Maalampi, J.; Enqvist, K.

1980-01-01

We show that the unification of the SO(10) families in SO(10+m) group can offer a solution to the neutrino mass problem. For simplicity we have restricted our analysis to SO(11), which contains - aside from generation mixing -the main novel feature of the theories of this kind: fermions that couple by V+A charged weak currents. (author)

Bose-fermi symmetries and SUSY in nuclei

International Nuclear Information System (INIS)

Casten, R.F.

1986-01-01

Most of the comparison with theory has compared energy levels and we have seen many beautiful examples of one-to-one level correspondences, sometimes supported with a few B(E2) values. However, what we really need to check, the author thinks, is the structural correspondence, to make sure these levels really correspond to each other, and that the energy level agreement is not just accidental; for that we need to look at transfer reactions, and more B(E2)'s. This brings up the very important question of the transfer operator. The author hopes that its importance can be seen in recent cases where a few B(E2)'s for a few transfer strengths have substantially changed the correspondence between theoretical and experimental levels even though the overall energy level agreement is neither better or worse. So it's clearly sensitive to that question. Also cases have been seen now where several different supergroups have been applied to the same regions, U(6/4) and U(6/20) for example, to the mass 130 region, and so the question of the single-particle spaces and the single-particle energies is an important one. The question of microscopic understanding of the parameters and the interactions, these bose-fermi symmetries is important since it probes the underlying physical basis. And finally there have be some very interesting, what the author calls ''exotic'' extensions of bose-fermi symmetry ideas presented at this meeting. One is the extension to odd-odd nuclei, another is the generalized SUSY extension that can apply to transition regions, and this is the interesting beta decay calculations of Dobes that were reported yesterday, and probably some others the author has missed

A flipped SO(10) model from Z{sub 6}-I orbifold

Energy Technology Data Exchange (ETDEWEB)

Shimojo, Masafumi [Fukui National Coll. of Technology, Sabae (Japan)

1994-08-01

We look for flipped SO(10) and flipped SU(5) models obtained from heterotic superstrings compactified on Z{sub 6}-I orbifold with one Wilson line. We obtain twelve/fifteen independent Wilson lines which give SO(10)/SU(5) models. While we cannot construct an SU(5) model whose sum of X-charge vanishes, we find only one chiral and modular anomaly-free spectrum with three generations of sixteen dimensional representations of SU(10) which may be matter fields. For the SO(10) model, we derive effective Yukawa couplings and examine the structure of mass matrices. We also comment on the breaking mechanism of the gauge group SO(10).

Lepton mixing and cancellation of the Dirac mass hierarchy in SO(10) GUTs with flavor symmetries T7 and Σ(81)

International Nuclear Information System (INIS)

Hagedorn, Claudia; Schmidt, Michael A.; Smirnov, Alexei Yu.

2009-01-01

In SO(10) grand unified theories the hierarchy which is present in the Dirac mass term of the neutrinos is generically as strong as the one in the up-type quark mass term. We propose a mechanism to partially or completely cancel this hierarchy in the light neutrino mass matrix in the seesaw context. The two main ingredients of the cancellation mechanism are the existence of three fermionic gauge singlets and of a discrete flavor symmetry G f which is broken at a higher scale than SO(10). Two realizations of the cancellation mechanism are presented. The realization based on the Frobenius group T 7 ≅Z 7 xZ 3 leads to a partial cancellation of the hierarchy and relates maximal 2-3 lepton mixing with the geometric hierarchy of the up-quark masses. In the realization with the group Σ(81) the cancellation is complete and tribimaximal lepton mixing is reproduced at the lowest order. In both cases, to fully accommodate the leptonic data we take into account additional effects such as effects of higher-dimensional operators involving more than one flavon. The heavy neutral fermion mass spectra are considered. For both realizations we analyze the flavon potential at the renormalizable level as well as ways to generate the Cabibbo angle.

Bremsstrahlung and Ion Beam Current Measurements with SuSI ECR Ion Source

International Nuclear Information System (INIS)

Ropponen, T.

2012-01-01

This series of slides presents: the Superconducting Source for Ions (SuSI), the X-ray measurement setup, the different collimation schemes, the flat B operation versus B(min) operation, and the impact of tuning ∇B while keeping fixed field profile

On the chirality of the SM and the fermion content of GUTs

Directory of Open Access Journals (Sweden)

Renato M. Fonseca

2015-08-01

Full Text Available The Standard Model (SM is a chiral theory, where right- and left-handed fermion fields transform differently under the gauge group. Extra fermions, if they do exist, need to be heavy otherwise they would have already been observed. With no complex mechanisms at work, such as confining interactions or extra-dimensions, this can only be achieved if every extra right-handed fermion comes paired with a left-handed one transforming in the same way under the Standard Model gauge group, otherwise the new states would only get a mass after electroweak symmetry breaking, which would necessarily be small (∼100 GeV. Such a simple requirement severely constrains the fermion content of Grand Unified Theories (GUTs. It is known for example that three copies of the representations 5¯+10 of SU(5 or three copies of the 16 of SO(10 can reproduce the Standard Model's chirality, but how unique are these arrangements? In a systematic way, this paper looks at the possibility of having non-standard mixtures of fermion GUT representations yielding the correct Standard Model chirality. Family unification is possible with large special unitary groups — for example, the 171 representation of SU(19 may decompose as 3(16+120+3(1 under SO(10.

The vacuum of the minimal nonsupersymmetric SO(10) unification

International Nuclear Information System (INIS)

Bertolini, Stefano; Di Luzio, Luca; Malinsky, Michal

2010-01-01

We study a class of nonsupersymmetric SO(10) grand-unified scenarios where the first stage of the symmetry breaking is driven by the vacuum expectation values of the 45-dimensional adjoint representation. Three-decade-old results claim that such a Higgs setting may lead exclusively to the flipped SU(5) x U(1) intermediate stage. We show that this conclusion is actually an artifact of the tree-level potential. The study of the accidental global symmetries emerging in various limits of the scalar potential offers a simple understanding of the tree-level result and a rationale for the drastic impact of quantum corrections. We scrutinize in detail the simplest and paradigmatic case of the 45 H +16 H Higgs sector triggering the breaking of SO(10) to the standard electroweak model. We show that the minimization of the one-loop effective potential allows for intermediate SU(4) C x SU(2) L x U(1) R and SU(3) c x SU(2) L x SU(2) R x U(1) B-L symmetric stages as well. These are the options favored by gauge unification. Our results, that apply whenever the SO(10) breaking is triggered by H >, open the path for hunting the simplest realistic scenario of nonsupersymmetric SO(10) grand unification.

Second Z in SO(10)

International Nuclear Information System (INIS)

Robinett, R.W.; Rosner, J.L.

1982-01-01

Models based on SO(10) are presented in which a second Z (''Z 2 '') can have a mass as low as 230 GeV/c 2 without appreciably distorting the lower-energy picture. In such models the lightest Z(''Z 1 '') is very close to the predicted mass in the standard picture, 1 greater than or equal to M(Z 1 )/M(Z 0 ) greater than or equal to 0.98. The major constraint preventing M(Z 2 ) from being even lower comes from experiments on parity violation in heavy atoms. Other properties of Z 2 , and ways to discover it, are discussed

New two-dimensional integrable quantum models from SUSY intertwining

International Nuclear Information System (INIS)

Ioffe, M V; Negro, J; Nieto, L M; Nishnianidze, D N

2006-01-01

Supersymmetrical intertwining relations of second order in the derivatives are investigated for the case of supercharges with deformed hyperbolic metric g ik = diag(1, - a 2 ). Several classes of particular solutions of these relations are found. The corresponding Hamiltonians do not allow the conventional separation of variables, but they commute with symmetry operators of fourth order in momenta. For some of these models the specific SUSY procedure of separation of variables is applied

Fine-tuning implications for complementary dark matter and LHC SUSY searches

CERN Document Server

Cassel, S; Kraml, S; Lessa, A; Ross, G G

2011-01-01

The requirement that SUSY should solve the hierarchy problem without undue fine-tuning imposes severe constraints on the new supersymmetric states. With the MSSM spectrum and soft SUSY breaking originating from universal scalar and gaugino masses at the Grand Unification scale, we show that the low-fine-tuned regions fall into two classes that will require complementary collider and dark matter searches to explore in the near future. The first class has relatively light gluinos or squarks which should be found by the LHC in its first run. We identify the multijet plus E_T^miss signal as the optimal channel and determine the discovery potential in the first run. The second class has heavier gluinos and squarks but the LSP has a significant Higgsino component and should be seen by the next generation of direct dark matter detection experiments. The combined information from the 7 TeV LHC run and the next generation of direct detection experiments can test almost all of the CMSSM parameter space consistent with ...

A low energy dynamical SUSY breaking scenario motivated from superstring derived unification

CERN Document Server

Faraggi, Alon E.

1996-01-01

Recently there has been a resurgence of interest in gauge mediated dynamical supersymmetry breaking scenarios. I investigate how low energy dynamical SUSY breaking may arise from superstring models. In a three generation string derived model I propose that the unbroken hidden non--Abelian gauge group at the string scale is SU(3)_H with matter multiplets. Due to the small gauge content of the hidden gauge group the supersymmetry breaking scale may be consistent with the dynamical SUSY breaking scenarios. The messenger states are obtained in the superstring model from sectors which arise due to the ``Wilson--line'' breaking of the unifying non--Abelian gauge symmetry. An important property of the string motivated messenger states is the absence of superpotential terms with the Standard Model states. The stringy symmetries therefore forbid the flavor changing processes which may arise due to couplings between the messenger sector states and the Standard Model states. Motivated from the problem of string gauge co...

Searching for the standard model in the string landscape: SUSY GUTs

International Nuclear Information System (INIS)

Raby, Stuart

2011-01-01

The standard model is the theory describing all observational data from the highest energies to the largest distances. (There is, however, one caveat: additional forms of energy, not part of the standard model, known as dark matter and dark energy must be included in order to describe the Universe at galactic scales and larger.) High energies refers to physics at the highest energy particle accelerators, including CERN's LEP II (which ceased operation in 2000 to begin construction of the Large Hadron Collider now in operation) and Fermilab's Tevatron, as well as to the energies obtained in particle jets created in so-called active galactic nuclei scattered throughout the visible Universe. Some of these extra-galactic particles bombard our own Earth in the form of cosmic rays, or super-energetic protons which scatter off nucei in the upper atmosphere. String theory is, on the other hand, an unfinished theoretical construct which attempts to describe all matter and their interactions in terms of the harmonic oscillations of open and/or closed strings. It is regarded as unfinished since at present it is a collection of ideas, tied together by powerful consistency conditions, called dualities, with the ultimate goal of finding the completed string theory. At the moment we only have descriptions which are valid in different mutually exclusive limits with names such as type I, IIA, IIB, heterotic, M and F theory. The string landscape has been described in the pages of many scholarly and popular works. It is perhaps best understood as the collection of possible solutions to the string equations; albeit these solutions look totally different in the different limiting descriptions. What do we know about the string landscape? We know that there are such a large number of possible solutions that the only way to represent this number is as 10 500 or a 1 followed by 500 zeros. Note that this is not a precise value since the uncertainty is given by a number just as large

Gauge-mediated supersymmetry breaking in string compactifications

International Nuclear Information System (INIS)

Diaconescu, Duiliu-Emanuel; Florea, Bogdan; Kachru, Shamit; Svrcek, Peter

2006-01-01

We provide string theory examples where a toy model of a SUSY GUT or the MSSM is embedded in a compactification along with a gauge sector which dynamically breaks supersymmetry. We argue that by changing microscopic details of the model (such as precise choices of flux), one can arrange for the dominant mediation mechanism transmitting SUSY breaking to the Standard Model to be either gravity mediation or gauge mediation. Systematic improvement of such examples may lead to top-down models incorporating a solution to the SUSY flavor problem

Gut

DEFF Research Database (Denmark)

Muscogiuri, Giovanna; Balercia, Giancarlo; Barrea, Luigi

2017-01-01

The gut regulates glucose and energy homeostasis; thus, the presence of ingested nutrients into the gut activates sensing mechanisms that affect both glucose homeostasis and regulate food intake. Increasing evidence suggest that gut may also play a key role in the pathogenesis of type 2 diabetes...... which may be related to both the intestinal microbiological profile and patterns of gut hormones secretion. Intestinal microbiota includes trillions of microorganisms but its composition and function may be adversely affected in type 2 diabetes. The intestinal microbiota may be responsible...... metabolism. Thus, the aim of this manuscript is to review the current evidence on the role of the gut in the pathogenesis of type 2 diabetes, taking into account both hormonal and microbiological aspects....

No-scale SUGRA SO(10) inflation

International Nuclear Information System (INIS)

Garg, Ila

2017-01-01

We show that a renormalizable theory based on gauge group SO(10) and Higgs system 10⊕210⊕126⊕126 with no scale supergravity can lead to a Starobinsky kind of potential for inflation. Successful inflation is possible in cases where the potential during inflation corresponds to SU(3)_C×SU(2)_L×SU(2)_R×U(1)_B_−_L, SU(5)×U(1) and flipped SU(5) × U(1) symmetries with suitable choice of superpotential parameters. The reheating in such a scenario can occur via non-perturbative decay of inflaton, i.e. through ‘preheating’. After the end of reheating, when Universe cools down, the finite-temperature potential can have a minimum which corresponds to MSSM. (author)

Diet strongly influences the gut microbiota of surgeonfishes

KAUST Repository

Miyake, Sou

2015-01-20

Intestinal tracts are among the most densely populated microbial ecosystems. Gut microbiota and their influence on the host have been well characterized in terrestrial vertebrates but much less so in fish. This is especially true for coral reef fishes, which are among the most abundant groups of vertebrates on earth. Surgeonfishes (family: Acanthuridae) are part of a large and diverse family of reef fish that display a wide range of feeding behaviours, which in turn has a strong impact on the reef ecology. Here, we studied the composition of the gut microbiota of nine surgeonfish and three nonsurgeonfish species from the Red Sea. High-throughput pyrosequencing results showed that members of the phylum Firmicutes, especially of the genus Epulopiscium, were dominant in the gut microbiota of seven surgeonfishes. Even so, there were large inter- and intraspecies differences in the diversity of surgeonfish microbiota. Replicates of the same host species shared only a small number of operational taxonomic units (OTUs), although these accounted for most of the sequences. There was a statistically significant correlation between the phylogeny of the host and their gut microbiota, but the two were not completely congruent. Notably, the gut microbiota of three nonsurgeonfish species clustered with some surgeonfish species. The microbiota of the macro- and microalgavores was distinct, while the microbiota of the others (carnivores, omnivores and detritivores) seemed to be transient and dynamic. Despite some anomalies, both host phylogeny and diet were important drivers for the intestinal microbial community structure of surgeonfishes from the Red Sea. © 2014 John Wiley & Sons Ltd.

N=2 extended supersymmetric GUTs

International Nuclear Information System (INIS)

Fayet, P.

1984-01-01

We construct N = 2 extended SUSY GUTs which provide a general association between massive spin-1 gauge bosons, spin-1/2 inos and spin-0 Higgs bosons. The corresponding gauge hypermultiplets are of four different types, while leptons and quarks are associated with mirror and spin-0 partners. The anticommutators of the two supersymmetry generators provide two spin-0 symmetry generators Zsub(s) and Zsub(p), which do not commute. Their field-independent parts and do commute, however, and appear as central charges in the symmetry algebra of the spontaneously broken gauge theory. These central charges and are linear combinations of global symmetry generators with grand unification generators such as the weak hypercharge (but not the electrical charge). They survive the electroweak symmetry breaking. They do not vanish for massive gauge hypermultiplets of types II and III, which verify M 2 = 2 + 2 > 0 and M 2 > 2 + 2 > 0, respectively. The formula M 2 approx.= 2 + 2 determines the mass spectrum on the grand unification scale, up to electroweak corrections. Finally, we indicate how our mass relations can be interpreted in a 5- or 6-dimensional formalism, the central charges appearing as the extra components of the covariant momentum along the compact fifth or sixth dimensions; and how to evaluate the grand unification mass msub(x) in terms of the lengths of the latter (msub(x)approx.=(h/2π)/Lsub(5(6))c). (orig./HSI)

Heterotic SO(32) model building in four dimensions

International Nuclear Information System (INIS)

Choi, K.S.; Groot Nibbelink, S.; Minnesota Univ., Minneapolis, MN; Trapletti, M.

2004-10-01

Four dimensional heterotic SO(32) orbifold models are classified systematically with model building applications in mind. We obtain all Z 3 , Z 7 and Z 2N models based on vectorial gauge shifts. The resulting gauge groups are reminiscent of those of type-I model building, as they always take the form SO(2n 0 ) x U(n 1 ) x.. x U(n N-1 ) x SO(2n N ). The complete twisted spectrum is determined simultaneously for all orbifold models in a parametric way depending on n 0 ,.., n N , rather than on a model by model basis. This reveals interesting patterns in the twisted states: They are always built out of vectors and anti-symmetric tensors of the U(n) groups, and either vectors or spinors of the SO(2n) groups. Our results may shed additional light on the S-duality between heterotic and type-I strings in four dimensions. As a spin-off we obtain an SO(10) GUT model with four generations from the Z 4 orbifold. (orig.)

Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis

DEFF Research Database (Denmark)

Kalaitzakis, Evangelos; Sadik, Riadh; Holst, Jens Juul

2008-01-01

BACKGROUND & AIMS: Liver cirrhosis is associated with increased prevalence of gastrointestinal symptoms, insulin resistance, and altered gut transit. We aimed to assess the prevalence of gut transit abnormalities in patients with cirrhosis, compared with healthy controls, and to evaluate the rela......BACKGROUND & AIMS: Liver cirrhosis is associated with increased prevalence of gastrointestinal symptoms, insulin resistance, and altered gut transit. We aimed to assess the prevalence of gut transit abnormalities in patients with cirrhosis, compared with healthy controls, and to evaluate...... the relation of gut transit with gastrointestinal symptoms and postprandial glucose and hormone profiles. METHODS: Half gastric emptying, small bowel residence, and colonic filling times were measured with a validated radiologic procedure in 42 consecutive patients with cirrhosis. In a subgroup of 25 patients......, gastrointestinal symptoms were evaluated by using a validated questionnaire and a caloric satiation test. Postprandial glucose, insulin, leptin, ghrelin, glucagon-like peptide 1, and PYY responses were also studied. Eighty-three healthy subjects served as controls for the transit studies and 10 for the hormone...

The structure of GUT breaking by orbifolding

International Nuclear Information System (INIS)

Hebecker, Arthur; March-Russell, John

2002-01-01

Recently, an attractive model of GUT breaking has been proposed in which a 5-dimensional supersymmetric SU(5) gauge theory on an S 1 /(Z 2 xZ 2 ') orbifold is broken down to the 4d MSSM by SU(5)-violating boundary conditions. Motivated by this construction and several related realistic models, we investigate the general structure of orbifolds in the effective field theory context, and of this orbifold symmetry breaking mechanism in particular. An analysis of the group theoretic structure of orbifold breaking is performed. This depends upon the existence of appropriate inner and outer automorphisms of the Lie algebra, and we show that a reduction of the rank of the GUT group is possible. Some aspects of larger GUT theories based on SO(10) and E 6 are discussed. We explore the possibilities of defining the theory directly on a space with boundaries and breaking the gauge symmetry by more general consistently chosen boundary conditions for the fields. Furthermore, we derive the relation of orbifold breaking with the familiar mechanism of Wilson line breaking, finding a one-to-one correspondence, both conceptually and technically. Finally, we analyse the consistency of orbifold models in the effective field theory context, emphasizing the necessity for self-adjoint extensions of the Hamiltonian and other conserved operators, and especially the highly restrictive anomaly cancellation conditions that apply if the bulk theory lives in more than 5 dimensions

Electroweak contributions to SUSY particle production processes at the LHC

International Nuclear Information System (INIS)

Mirabella, Edoardo

2009-01-01

In this thesis we have computed the electroweak contributions of O(α s α), O(α 2 ) and O(α s 2 ) to three different classes of processes leading to the hadronic production of the SUSY partners of quarks and gluons, i.e. squarks and gluinos. The theoretical framework is the Minimal Supersymmetric extension of the Standard Model, the MSSM. The three processes are gluino pair production, diagonal squark-antisquark and associated squark-gluino production.

Feed additives shift gut microbiota and enrich antibiotic resistance in swine gut.

Science.gov (United States)

Zhao, Yi; Su, Jian-Qiang; An, Xin-Li; Huang, Fu-Yi; Rensing, Christopher; Brandt, Kristian Koefoed; Zhu, Yong-Guan

2018-04-15

Antibiotic resistance genes (ARGs) are emerging environmental contaminants posing a threat to public health. Antibiotics and metals are widely used as feed additives and could consequently affect ARGs in swine gut. In this study, high-throughput quantitative polymerase chain reaction (HT-qPCR) based ARG chip and next-generation 16S rRNA gene amplicon sequencing data were analyzed using multiple statistical approaches to profile the antibiotic resistome and investigate its linkages to antibiotics and metals used as feed additives and to the microbial community composition in freshly collected swine manure samples from three large-scale Chinese pig farms. A total of 146 ARGs and up to 1.3×10 10 total ARG copies per gram of swine feces were detected. ARGs conferring resistance to aminoglycoside, macrolide-lincosamide-streptogramin B (MLSB) and tetracycline were dominant in pig gut. Total abundance of ARGs was positively correlated with in-feed antibiotics, microbial biomass and abundance of mobile genetic elements (MGEs) (Padditives and community composition (16.5%). These results suggest that increased levels of in-feed additives could aggravate the enrichment of ARGs and MGEs in swine gut. Copyright © 2017 Elsevier B.V. All rights reserved.

Symmetry breaking of SO(10) and constraints on Higgs potential, (1)

International Nuclear Information System (INIS)

Yasue, Masaki.

1980-08-01

The symmetry breaking of SO(10) is studied in the tree approximation of the potential for an adjoint (45) representation and a spinorial (16) representation. The potential can break SO(10) down to SU(3)sub(c) x SU(2)sub(L) x U(1). It is not allowed to break SO(10) down to SU(3)sub(c) x U(1)sub(em) via SU(3)sub(c) x SU(2)sub(L) x U(1) even in the presence of a cubic (16) (16*) (45) coupling. Instead, SU(3) x U(1) comes from SU(4) x U(1). The masses for the physical Higgs scalars are calculated in SU(3)sub(c) x SU(2)sub(L) x U(1). The dynamically allowed region of the vacuum expectation values of the (45) is found to be strongly restricted. As a result, SO(6) and SO(4) cannot show up in the course of the breaking. (author)

The impact of the postnatal gut microbiota on animal models

DEFF Research Database (Denmark)

Hansen, Axel Jacob Kornerup; Ejsing-Duun, Maria; Aasted, Bent

2007-01-01

Quality control of laboratory animals has been mostly concentrated on eliminating and securing the absence of specific infections, but event barrier bred laboratory animals harbour a huge number of gut bacteria. There is scientific evidence that the nature of the gut microbiota especially in early...... correlated to factors related to early exposure to microorganisms, e.g. the so-called hygiene hypothesis claims that the increasing human incidence of allergy. T1D, RA and IBD may be due to the lack of such exposure. It is possible today by various molecular techniques to profile the gut microbiota...

Standard coupling unification in SO(10), hybrid seesaw neutrino mass and leptogenesis, dark matter, and proton lifetime predictions

Energy Technology Data Exchange (ETDEWEB)

Parida, M.K.; Nayak, Bidyut Prava; Satpathy, Rajesh [Centre of Excellence in Theoretical and Mathematical Sciences,Siksha ‘O’ Anusandhan University,Khandagiri Square, Bhubaneswar 751030 (India); Awasthi, Ram Lal [Indian Institute of Science Education and Research,Knowledge City, Sector 81, SAS Nagar, Manauli 140306 (India)

2017-04-12

We discuss gauge coupling unification of SU(3){sub C}×SU(2){sub L}×U(1){sub Y} descending directly from non-supersymmetric SO(10) while providing solutions to the three outstanding problems of the standard model: neutrino masses, dark matter, and the baryon asymmetry of the universe. Conservation of matter parity as gauged discrete symmetry for the stability and identification of dark matter in the model calls for high-scale spontaneous symmetry breaking through 126{sub H} Higgs representation. This naturally leads to the hybrid seesaw formula for neutrino masses mediated by heavy scalar triplet and right-handed neutrinos. Being quadratic in the Majorana coupling, the seesaw formula predicts two distinct patterns of right-handed neutrino masses, one hierarchical and another not so hierarchical (or compact), when fitted with the neutrino oscillation data. Predictions of the baryon asymmetry via leptogenesis are investigated through the decays of both the patterns of RHν masses. A complete flavor analysis has been carried out to compute CP-asymmetries including washouts and solutions to Boltzmann equations have been utilised to predict the baryon asymmetry. The additional contribution to vertex correction mediated by the heavy left-handed triplet scalar is noted to contribute as dominantly as other Feynman diagrams. We have found successful predictions of the baryon asymmetry for both the patterns of right-handed neutrino masses. The SU(2){sub L} triplet fermionic dark matter at the TeV scale carrying even matter parity is naturally embedded into the non-standard fermionic representation 45{sub F} of SO(10). In addition to the triplet scalar and the triplet fermion, the model needs a nonstandard color octet fermion of mass ∼5×10{sup 7} GeV to achieve precision gauge coupling unification at the GUT mass scale M{sub U}{sup 0}=10{sup 15.56} GeV. Threshold corrections due to superheavy components of 126{sub H} and other representations are estimated and found to be

The toric SO(10) F-theory landscape

International Nuclear Information System (INIS)

Buchmuller, W.; Dierigl, M.; Oehlmann, P.K.; Ruehle, F.

2017-09-01

Supergravity theories in more than four dimensions with grand unified gauge symmetries are an important intermediate step towards the ultraviolet completion of the Standard Model in string theory. Using toric geometry, we classify and analyze six-dimensional F-theory vacua with gauge group SO(10) taking into account Mordell-Weil U(1) and discrete gauge factors. We determine the full matter spectrum of these models, including charged and neutral SO(10) singlets. Based solely on the geometry, we compute all matter multiplicities and confirm the cancellation of gauge and gravitational anomalies independent of the base space. Particular emphasis is put on symmetry enhancements at the loci of matter fields and to the frequent appearance of superconformal points. They are linked to non-toric Kaehler deformations which contribute to the counting of degrees of freedom. We compute the anomaly coefficients for these theories as well by using a base-independent blow-up procedure and superconformal matter transitions. Finally, we identify six-dimensional supergravity models which can yield the Standard Model with high-scale supersymmetry by further compactification to four dimensions in an Abelian flux background.

The toric SO(10) F-theory landscape

Energy Technology Data Exchange (ETDEWEB)

Buchmuller, W.; Dierigl, M.; Oehlmann, P.K. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Ruehle, F. [Oxford Univ. (United Kingdom). Rudolf Peierls Centre for Theoretical Physics

2017-09-15

Supergravity theories in more than four dimensions with grand unified gauge symmetries are an important intermediate step towards the ultraviolet completion of the Standard Model in string theory. Using toric geometry, we classify and analyze six-dimensional F-theory vacua with gauge group SO(10) taking into account Mordell-Weil U(1) and discrete gauge factors. We determine the full matter spectrum of these models, including charged and neutral SO(10) singlets. Based solely on the geometry, we compute all matter multiplicities and confirm the cancellation of gauge and gravitational anomalies independent of the base space. Particular emphasis is put on symmetry enhancements at the loci of matter fields and to the frequent appearance of superconformal points. They are linked to non-toric Kaehler deformations which contribute to the counting of degrees of freedom. We compute the anomaly coefficients for these theories as well by using a base-independent blow-up procedure and superconformal matter transitions. Finally, we identify six-dimensional supergravity models which can yield the Standard Model with high-scale supersymmetry by further compactification to four dimensions in an Abelian flux background.

Generalized Jaynes-Cummings Hamiltonians by shape-invariant hierarchies and their SUSY partners

International Nuclear Information System (INIS)

Hussin, V; Kuru, S; Negro, J

2006-01-01

A generalization of the matrix Jaynes-Cummings model in the rotating wave approximation is proposed by means of the shape-invariant hierarchies of scalar factorized Hamiltonians. A class of Darboux transformations (sometimes called SUSY transformations in this context) suitable for these generalized Jaynes-Cummings models is constructed. Finally one example is worked out using the methods developed

Early-life gut microbiome and egg allergy.

Science.gov (United States)

Fazlollahi, M; Chun, Y; Grishin, A; Wood, R A; Burks, A W; Dawson, P; Jones, S M; Leung, D Y M; Sampson, H A; Sicherer, S H; Bunyavanich, S

2018-07-01

Gut microbiota may play a role in egg allergy. We sought to examine the association between early-life gut microbiota and egg allergy. We studied 141 children with egg allergy and controls from the multicenter Consortium of Food Allergy Research study. At enrollment (age 3 to 16 months), fecal samples were collected, and clinical evaluation, egg-specific IgE measurement, and egg skin prick test were performed. Gut microbiome was profiled by 16S rRNA sequencing. Analyses for the primary outcome of egg allergy at enrollment, and the secondary outcomes of egg sensitization at enrollment and resolution of egg allergy by age 8 years, were performed using Quantitative Insights into Microbial Ecology, Phylogenetic Investigation of Communities by Reconstruction of Unobserved States, and Statistical Analysis of Metagenomic Profiles. Compared to controls, increased alpha diversity and distinct taxa (PERMANOVA P = 5.0 × 10 -4 ) characterized the early-life gut microbiome of children with egg allergy. Genera from the Lachnospiraceae, Streptococcaceae, and Leuconostocaceae families were differentially abundant in children with egg allergy. Predicted metagenome functional analyses showed differential purine metabolism by the gut microbiota of egg-allergic subjects (Kruskal-Wallis P adj  = 0.021). Greater gut microbiome diversity and genera from Lachnospiraceae and Ruminococcaceae were associated with egg sensitization (PERMANOVA P = 5.0 × 10 -4 ). Among those with egg allergy, there was no association between early-life gut microbiota and egg allergy resolution by age 8 years. The distinct early-life gut microbiota in egg-allergic and egg-sensitized children identified by our study may point to targets for preventive or therapeutic intervention. © 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Bacterial Impact on the Gut Metabolome

DEFF Research Database (Denmark)

Sulek, Karolina; Wilcks, Andrea; Licht, Tine Rask

During the last decade, it has become evident that the complex ecosystem of mi-crobes inhabiting the human gut plays an important role for human health. An in-creasing number of publications have shown that the composition and activity of our intestinal microbiota affects a number of different so...

Electroweak contributions to SUSY particle production processes at the LHC

Energy Technology Data Exchange (ETDEWEB)

Mirabella, Edoardo

2009-07-22

In this thesis we have computed the electroweak contributions of O({alpha}{sub s}{alpha}), O({alpha}{sup 2}) and O({alpha}{sub s}{sup 2}) to three different classes of processes leading to the hadronic production of the SUSY partners of quarks and gluons, i.e. squarks and gluinos. The theoretical framework is the Minimal Supersymmetric extension of the Standard Model, the MSSM. The three processes are gluino pair production, diagonal squark-antisquark and associated squark-gluino production.

Direct gauge mediation of uplifted metastable supersymmetry breaking in supergravity

International Nuclear Information System (INIS)

Maru, Nobuhito

2010-01-01

We propose a direct gauge mediation model based on an uplifted metastable supersymmetry (SUSY) breaking coupled to supergravity. A constant superpotential plays an essential role to fix the moduli as well as breaking SUSY and R symmetry and the cancellation of the cosmological constant. Gaugino masses are generated at leading order of SUSY breaking scale, and comparable to the sfermion masses as in the ordinary gauge mediation. The Landau pole problem for QCD coupling can be easily solved since more than half of messengers become superheavy, which are heavier than the grand unified theory (GUT) scale.

A comment on the quark mixing in the supersymmetric SU(4)xO(4) GUT model

International Nuclear Information System (INIS)

Ranfone, S.

1992-08-01

The SU(4) x O(4) and the ''flipped'' SU(5) x U(1) models seem to be the only possible Grand Universal Theories (GUT's) derivable from string theories with Kac-Moody level K=1. Naively, the SU(4) x O(4) model, at least in its minimal GUT version, is characterized by the lack of any mixing in the quark sector. In this ''Comment'' we show that, although some mixing may be generated as a consequence of large vacuum-expectation-values for the scalar partners of the right-handed neutrinos, it turns out to be too small by several orders of magnitude, in net contrast with our experimental information concerning the Cabibbo mixing. Our result, which therefore rules out the minimal SU(4) x O(4) GUT model, also applies to ''flipped'' SU(5) x U(1) in the case of the embedding in SO(10). (Author)

Finite N=1 SUSY gauge field theories

International Nuclear Information System (INIS)

Kazakov, D.I.

1986-01-01

The authors give a detailed description of the method to construct finite N=1 SUSY gauge field theories in the framework of N=1 superfields within dimensional regularization. The finiteness of all Green functions is based on supersymmetry and gauge invariance and is achieved by a proper choice of matter content of the theory and Yukawa couplings in the form Y i =f i (ε)g, where g is the gauge coupling, and the function f i (ε) is regular at ε=0 and is calculated in perturbation theory. Necessary and sufficient conditions for finiteness are determined already in the one-loop approximation. The correspondence with an earlier proposed approach to construct finite theories based on aigenvalue solutions of renormalization-group equations is established

Search for Nucleon Decays in Super-Kamiokande

International Nuclear Information System (INIS)

Miura, Makoto

2010-01-01

Grand Unified Theories (GUTs) is motivated by merging of the coupling constants of the strong, weak, and electromagnetic forces at a large energy scale (∼10 16 GeV), which is out of the reach of accelerators. One of the other general features of GUTs is that they allow lepton and baryon number violations and they predict instability of nucleons. Then nucleon decay experiments are the direct probe for GUTs. The Super-Kamiokande (SK) is a water Cherenkov detector which keeps running to detect nucleon decays with large mass. There are no other nucleon decay detectors which have as long exposure as SK. The results of nucleon decay search based on 173 kton year (1996-2008) will be presented in the conference.The favored decay mode in GUTs based on SU(5) symmetry is p→e + π 0 . On the other hand, p→ν K + is favored by SUSY GUTs model. Those two modes will be mainly discussed. (authors)

Gut Microbiota-brain Axis

Institute of Scientific and Technical Information of China (English)

Hong-Xing Wang; Yu-Ping Wang

2016-01-01

Objective:To systematically review the updated information about the gut microbiota-brain axis.Data Sources:All articles about gut microbiota-brain axis published up to July 18,2016,were identified through a literature search on PubMed,ScienceDirect,and Web of Science,with the keywords of"gut microbiota","gut-brain axis",and "neuroscience".Study Selection:All relevant articles on gut microbiota and gut-brain axis were included and carefully reviewed,with no limitation of study design.Results:It is well-recognized that gut microbiota affects the brain's physiological,behavioral,and cognitive functions although its precise mechanism has not yet been fully understood.Gut microbiota-brain axis may include gut microbiota and their metabolic products,enteric nervous system,sympathetic and parasympathetic branches within the autonomic nervous system,neural-immune system,neuroendocrine system,and central nervous system.Moreover,there may be five communication routes between gut microbiota and brain,including the gut-brain's neural network,neuroendocrine-hypothalamic-pituitary-adrenal axis,gut immune system,some neurotransmitters and neural regulators synthesized by gut bacteria,and barrier paths including intestinal mucosal barrier and blood-brain barrier.The microbiome is used to define the composition and functional characteristics of gut microbiota,and metagenomics is an appropriate technique to characterize gut microbiota.Conclusions:Gut microbiota-brain axis refers to a bidirectional information network between the gut microbiota and the brain,which may provide a new way to protect the brain in the near future.

SUSY-QCD corrections to Higgs boson production at hadron colliders

International Nuclear Information System (INIS)

Djouadi, A.; Spira, M.

1999-12-01

We analyze the next-to-leading order SUSY-QCD corrections to the production of Higgs particles at hadron colliders in supersymmetric extensions of the standard model. Besides the standard QCD corrections due to gluon exchange and emission, genuine supersymmetric corrections due to the virtual exchange of squarks and gluinos are present. At both the Tevatron and the LHC, these corrections are found to be small in the Higgs-strahlung, Drell-Yan-like Higgs pair production and vector boson fusion processes. (orig.)

A Layman's guide to SUSY GUTs

CERN Document Server

López, Jorge L; Zichichi, A

1994-01-01

The determination of the most straightforward evidence for the existence of the Superworld requires a guide for non-experts (especially experimental physicists) for them to make their own judgement on the value of such predictions. For this purpose we review the most basic results of Super-Grand unification in a simple and clear way. We focus the attention on two specific models and their predictions. These two models represent an example of a direct comparison between a traditional unified-theory and a string-inspired approach to the solution of the many open problems of the Standard Model. We emphasize that viable models must satisfy {\\em all} available experimental constraints and be as simple as theoretically possible. The two well defined supergravity models, $SU(5)$ and $SU(5)\\times U(1)$, can be described in terms of only a few parameters (five and three respectively) instead of the more than twenty needed in the MSSM model, \\ie, the Minimal Supersymmetric extension of the Standard Model. A case of spe...

Rencontres de Moriond QCD 2012: Searches for Dark Matter, SUSY and other exotic particles

CERN Multimedia

CERN Bulletin

2012-01-01

The fact that SUSY and other new physics signals do not seem to hide in “obvious” places is bringing a healthy excitement to Moriond. Yesterday’s presentations confirmed that, with the 2012 LHC data, experiments will concentrate on searches for exotic particles that might decay into yet unexplored modes. In the meantime, they are setting unprecedented boundaries to regions where new particles (not just SUSY) could exist. The limits of what particle accelerators can bring to enlighten the mystery of Dark Matter were also presented and discussed.   Each bar on the picture represents a decay channel that the ATLAS Collaboration (top) and the CMS Collaborations (bottom) have analysed.  The value indicated on the scale (or on the relevant bar) defines the maximum mass that the particle in that search cannot have. Not knowing what kind of new physics we should really expect, and given the fact that it does not seem to be hiding in any of the obvious places, e...

Neutralino Dark Matter in non-universal and non-minimal SUSY

International Nuclear Information System (INIS)

King, S.F.

2010-01-01

We discuss neutralino dark matter in non-universal SUSY including the NUHM, SU(5) with non-universal gauginos. In the MSSM we argue from naturalness that non-universal soft mass parameters are preferred, with non-universal gaugino masses enabling supernatural dark matter beyond the MSSM, we also discuss neutralino dark matter in the U SSM and E 6 SSM. In the E 6 SSM a light neutralino LSP coming from the inert Higgsino and singlino sector is unavoidable and makes an attractive dark matter candidate.

Polymers in the gut compress the colonic mucus hydrogel.

Science.gov (United States)

Datta, Sujit S; Preska Steinberg, Asher; Ismagilov, Rustem F

2016-06-28

Colonic mucus is a key biological hydrogel that protects the gut from infection and physical damage and mediates host-microbe interactions and drug delivery. However, little is known about how its structure is influenced by materials it comes into contact with regularly. For example, the gut abounds in polymers such as dietary fibers or administered therapeutics, yet whether such polymers interact with the mucus hydrogel, and if so, how, remains unclear. Although several biological processes have been identified as potential regulators of mucus structure, the polymeric composition of the gut environment has been ignored. Here, we demonstrate that gut polymers do in fact regulate mucus hydrogel structure, and that polymer-mucus interactions can be described using a thermodynamic model based on Flory-Huggins solution theory. We found that both dietary and therapeutic polymers dramatically compressed murine colonic mucus ex vivo and in vivo. This behavior depended strongly on both polymer concentration and molecular weight, in agreement with the predictions of our thermodynamic model. Moreover, exposure to polymer-rich luminal fluid from germ-free mice strongly compressed the mucus hydrogel, whereas exposure to luminal fluid from specific-pathogen-free mice-whose microbiota degrade gut polymers-did not; this suggests that gut microbes modulate mucus structure by degrading polymers. These findings highlight the role of mucus as a responsive biomaterial, and reveal a mechanism of mucus restructuring that must be integrated into the design and interpretation of studies involving therapeutic polymers, dietary fibers, and fiber-degrading gut microbes.

External meeting: UNIVERSITE DE GENEVE

CERN Multimedia

2007-01-01

Ecole de physique Département de physique nucléaire et corspusculaire 24, Quai Ernest-Ansermet 1211 GENEVE 4 Tél: (022) 379 62 73 Fax: (022) 379 69 92 Wednesday 13th June 2007 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium A sensitive test of supersymmetric-GUT theories: the MEG experiment at PSI by Prof. A. Baldini, INFN, Pisa The μ -> e gamma decay, which is absent in the Standard Model, is instead foreseen to occur in supersymmetric grand unified theories (SUSY-GUT) with a branching ratio which should be detectable by the MEG experiment. In this seminar the SUSY-GUT predictions for the μ -> e gamma decay rate and the connection with neutrino oscillations will be illustrated. The status of the MEG experiment will be described and the foreseen experimental sensitivity to the μ -> e gamma decay will be shown. Information : http://dpnc.unige.ch/seminaire/annonce.html Organizer : J.-S. Graulich

[Gut microbiota: Description, role and pathophysiologic implications].

Science.gov (United States)

Landman, C; Quévrain, E

2016-06-01

The human gut contains 10(14) bacteria and many other micro-organisms such as Archaea, viruses and fungi. Studying the gut microbiota showed how this entity participates to gut physiology and beyond this to human health, as a real "hidden organ". In this review, we aimed to bring information about gut microbiota, its structure, its roles and its implication in human pathology. After bacterial colonization in infant, intestinal microbial composition is unique for each individual although more than 95% can be assigned to four major phyla. The use of culture independent methods and more recently the development of high throughput sequencing allowed to depict precisely gut microbiota structure and diversity as well as its alteration in diseases. Gut microbiota is implicated in the maturation of the host immune system and in many fundamental metabolic pathways including sugars and proteins fermentation and metabolism of bile acids and xenobiotics. Imbalance of gut microbial populations or dysbiosis has important functional consequences and is implicated in many digestive diseases (inflammatory bowel diseases, colorectal cancer, etc.) but also in obesity and autism. These observations have led to a surge of studies exploring therapeutics which aims to restore gut microbiota equilibrium such as probiotics or fecal microbiota transplantation. But recent research also investigates biological activity of microbial products which could lead to interesting therapeutics leads. Copyright © 2015 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

Prospects for (non-SUSY) new physics with first LHC data

International Nuclear Information System (INIS)

Butterworth, Jonathan

2007-01-01

The ATLAS and CMS experiments will take first data soon. I consider here the prospects for new physics (excluding SUSY) with a few fb -1 of data. This means processes with signal cross sections of a few 100 fb or less, with clear and fairly simple signatures--precision comparison of data to Standard Model tails will take longer, needing more luminosity and very good understanding of detector calibrations, resolutions and trigger efficiencies. The approach I take here is signature rather than model based, but examples of models will be given

Extension of the SUSY Les Houches Accord 2 for see-saw mechanisms

International Nuclear Information System (INIS)

Basso, L.; Belyaev, A.; Chowdhury, D.; Ghosh, D.K.; Hirsch, M.; Khalil, S.; Moretti, S.; O'Leary, B.; Porod, W.; Staub, F.

2012-01-01

The SUSY Les Houches Accord (SLHA) 2 extended the first SLHA to include various generalisations of the Minimal Supersymmetric Standard Model (MSSM) as well as its simplest next-to-minimal version. Here, we propose further extensions to it, to include the most general and well-established see-saw descriptions (types I/II/III, inverse, and linear) in both an effective and a simple gauged extension of the MSSM framework. (authors)

Squark and slepton masses as probes of supersymmetric SO(10) unification

Energy Technology Data Exchange (ETDEWEB)

Balasubramanian Ananthanarayan; P. N. Pandita

2003-09-01

We carry out a detailed analysis of the non-universal supersymmetry breaking scalar masses arising in SO(10) supersymmetric unification. By considering patterns of squark and slepton masses, we show that a set of sum rules for the sfermion masses is independent of the manner in which SO(10) breaks. We discuss the reasons for this remarkable result. The phenomenology arising from such non-universality is shown to be practically unaffected by the symmetry breaking pattern.

SUSY S4×SU(5) revisited

International Nuclear Information System (INIS)

Hagedorn, Claudia; King, Stephen F.; Luhn, Christoph

2012-01-01

Following the recent results from Daya Bay and RENO, which measure the lepton mixing angle θ 13 l ≈0.15, we revisit a supersymmetric (SUSY) S 4 ×SU(5) model, which predicts tri-bimaximal (TB) mixing in the neutrino sector with θ 13 l being too small in its original version. We show that introducing one additional S 4 singlet flavon into the model gives rise to a sizable θ 13 l via an operator which leads to the breaking of one of the two Z 2 symmetries preserved in the neutrino sector at leading order (LO). The results of the original model for fermion masses, quark mixing and the solar mixing angle are maintained to good precision. The atmospheric and solar mixing angle deviations from TB mixing are subject to simple sum rule bounds.

Search for SUSY with two same-sign leptons or three leptons and jets at $\\sqrt{s} = 13 \\text{ TeV}$ with the ATLAS Detector

CERN Document Server

Liu, Yang; The ATLAS collaboration

2017-01-01

Supersymmetry (SUSY) is a well motivated extension of the Standard Model (SM) that postulates the existence of a superpartner for each SM particle. A search for strongly produced SUSY particles decaying to a pair of two isolated \\textbf{same-sign leptons (SS)} or \\textbf{three leptons (3L)} has been carried out using the complete data set collected by the ATLAS experiment in 2015-16 at 13 TeV ($36.5 fb^{-1}$). The analysis benefits from a low SM background and uses looser kinematic requirements compared to other beyond the SM (BSM) searches which increases its sensitivity to scenarios with small mass differences between the SUSY particles, or in which R-parity is not conserved. The results are interpreted in the context of \\textbf{R-parity conserving (RPC)} or \\textbf{R-parity violating (RPV)} simplified signal models

Embracing the gut microbiota: the new frontier for inflammatory and infectious diseases

Science.gov (United States)

van den Elsen, Lieke WJ; Poyntz, Hazel C; Weyrich, Laura S; Young, Wayne; Forbes-Blom, Elizabeth E

2017-01-01

The gut microbiota provides essential signals for the development and appropriate function of the immune system. Through this critical contribution to immune fitness, the gut microbiota has a key role in health and disease. Recent advances in the technological applications to study microbial communities and their functions have contributed to a rapid increase in host–microbiota research. Although it still remains difficult to define a so-called ‘normal' or ‘healthy' microbial composition, alterations in the gut microbiota have been shown to influence the susceptibility of the host to different diseases. Current translational research combined with recent technological and computational advances have enabled in-depth study of the link between microbial composition and immune function, addressing the interplay between the gut microbiota and immune responses. As such, beneficial modulation of the gut microbiota is a promising clinical target for many prevalent diseases including inflammatory bowel disease, metabolic abnormalities such as obesity, reduced insulin sensitivity and low-grade inflammation, allergy and protective immunity against infections. PMID:28197336

New minimal SO(10) GUT: A theory for all epochs

Indian Academy of Sciences (India)

2016-01-07

Jan 7, 2016 ... Measurable or near measurable level of tensor perturbations – and thus large inflaton mass scale – may be accommodated within the NMSGUT by supersymmetric see-saw inflation based on an LHN flat direction inflaton if the Higgs component contains contributions from heavy Higgs components.

GUTs without guts

Energy Technology Data Exchange (ETDEWEB)

Gato-Rivera, B. [NIKHEF Theory Group, Science Park 105, 1098 XG Amsterdam (Netherlands); Instituto de Física Fundamental, IFF-CSIC, Serrano 123, Madrid 28006 (Spain); Schellekens, A.N., E-mail: t58@nikhef.nl [NIKHEF Theory Group, Science Park 105, 1098 XG Amsterdam (Netherlands); Instituto de Física Fundamental, IFF-CSIC, Serrano 123, Madrid 28006 (Spain); IMAPP, Radboud Universiteit, Nijmegen (Netherlands)

2014-06-15

The structure of a Standard Model family is derived in a class of brane models with a U(M)×U(N) factor, from two mildly anthropic requirements: a massless photon and a universe that does not turn into a plasma of massless charged particles. If we choose M=3 and N=2, the only option is shown to be the Standard Model with an undetermined number of families. We do not assume the U(1) embedding, charge quantization, family repetition, nor the fermion representations; all of these features are derived, assuming a doublet Higgs. With a slightly stronger assumption even the Higgs representation is determined. We also consider a more general class, requiring an asymptotically free strong SU(M) (with M⩾3) interaction from the first factor and an electromagnetic U(1) embedded in both factors. We allow Higgs symmetry breaking of the U(N)×U(1) flavor group by at most one Higgs boson in any representation, combined with any allowed chiral symmetry breaking by SU(M). For M=3 there is a large number of solutions with an unbroken U(1). In all of these, “quarks” have third-integral charges and color singlets have integer charges in comparison to leptons. Hence Standard Model charge quantization holds for any N. Only for N=2 these models allow an SU(5) GUT extension, but this extension offers no advantages whatsoever for understanding the Standard Model; it only causes complications, such as the doublet–triplet splitting problem. Although all these models have a massless photon, all except the Standard Model are ruled out by the second anthropic requirement. In this class of brane models the Standard Model is realized as a GUT with its intestines removed, to keep only the good parts: a GUT without guts.

GUTs without guts

International Nuclear Information System (INIS)

Gato-Rivera, B.; Schellekens, A.N.

2014-01-01

The structure of a Standard Model family is derived in a class of brane models with a U(M)×U(N) factor, from two mildly anthropic requirements: a massless photon and a universe that does not turn into a plasma of massless charged particles. If we choose M=3 and N=2, the only option is shown to be the Standard Model with an undetermined number of families. We do not assume the U(1) embedding, charge quantization, family repetition, nor the fermion representations; all of these features are derived, assuming a doublet Higgs. With a slightly stronger assumption even the Higgs representation is determined. We also consider a more general class, requiring an asymptotically free strong SU(M) (with M⩾3) interaction from the first factor and an electromagnetic U(1) embedded in both factors. We allow Higgs symmetry breaking of the U(N)×U(1) flavor group by at most one Higgs boson in any representation, combined with any allowed chiral symmetry breaking by SU(M). For M=3 there is a large number of solutions with an unbroken U(1). In all of these, “quarks” have third-integral charges and color singlets have integer charges in comparison to leptons. Hence Standard Model charge quantization holds for any N. Only for N=2 these models allow an SU(5) GUT extension, but this extension offers no advantages whatsoever for understanding the Standard Model; it only causes complications, such as the doublet–triplet splitting problem. Although all these models have a massless photon, all except the Standard Model are ruled out by the second anthropic requirement. In this class of brane models the Standard Model is realized as a GUT with its intestines removed, to keep only the good parts: a GUT without guts

Mind-altering with the gut: Modulation of the gut-brain axis with probiotics.

Science.gov (United States)

Kim, Namhee; Yun, Misun; Oh, Young Joon; Choi, Hak-Jong

2018-03-01

It is increasingly evident that bidirectional interactions exist among the gastrointestinal tract, the enteric nervous system, and the central nervous system. Recent preclinical and clinical trials have shown that gut microbiota plays an important role in these gut-brain interactions. Furthermore, alterations in gut microbiota composition may be associated with pathogenesis of various neurological disorders, including stress, autism, depression, Parkinson's disease, and Alzheimer's disease. Therefore, the concepts of the microbiota-gut-brain axis is emerging. Here, we review the role of gut microbiota in bidirectional interactions between the gut and the brain, including neural, immune-mediated, and metabolic mechanisms. We highlight recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders via the gut-brain axis.

Control of lupus nephritis by changes of gut microbiota.

Science.gov (United States)

Mu, Qinghui; Zhang, Husen; Liao, Xiaofeng; Lin, Kaisen; Liu, Hualan; Edwards, Michael R; Ahmed, S Ansar; Yuan, Ruoxi; Li, Liwu; Cecere, Thomas E; Branson, David B; Kirby, Jay L; Goswami, Poorna; Leeth, Caroline M; Read, Kaitlin A; Oestreich, Kenneth J; Vieson, Miranda D; Reilly, Christopher M; Luo, Xin M

2017-07-11

Systemic lupus erythematosus, characterized by persistent inflammation, is a complex autoimmune disorder with no known cure. Immunosuppressants used in treatment put patients at a higher risk of infections. New knowledge of disease modulators, such as symbiotic bacteria, can enable fine-tuning of parts of the immune system, rather than suppressing it altogether. Dysbiosis of gut microbiota promotes autoimmune disorders that damage extraintestinal organs. Here we report a role of gut microbiota in the pathogenesis of renal dysfunction in lupus. Using a classical model of lupus nephritis, MRL/lpr, we found a marked depletion of Lactobacillales in the gut microbiota. Increasing Lactobacillales in the gut improved renal function of these mice and prolonged their survival. We used a mixture of 5 Lactobacillus strains (Lactobacillus oris, Lactobacillus rhamnosus, Lactobacillus reuteri, Lactobacillus johnsonii, and Lactobacillus gasseri), but L. reuteri and an uncultured Lactobacillus sp. accounted for most of the observed effects. Further studies revealed that MRL/lpr mice possessed a "leaky" gut, which was reversed by increased Lactobacillus colonization. Lactobacillus treatment contributed to an anti-inflammatory environment by decreasing IL-6 and increasing IL-10 production in the gut. In the circulation, Lactobacillus treatment increased IL-10 and decreased IgG2a that is considered to be a major immune deposit in the kidney of MRL/lpr mice. Inside the kidney, Lactobacillus treatment also skewed the Treg-Th17 balance towards a Treg phenotype. These beneficial effects were present in female and castrated male mice, but not in intact males, suggesting that the gut microbiota controls lupus nephritis in a sex hormone-dependent manner. This work demonstrates essential mechanisms on how changes of the gut microbiota regulate lupus-associated immune responses in mice. Future studies are warranted to determine if these results can be replicated in human subjects.

The human gut resistome.

Science.gov (United States)

van Schaik, Willem

2015-06-05

In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain. The human gut contains a densely populated microbial ecosystem, termed the gut microbiota, which offers ample opportunities for the horizontal transfer of genetic material, including antibiotic resistance genes. Recent technological advances allow microbiota-wide studies into the diversity and dynamics of the antibiotic resistance genes that are harboured by the gut microbiota ('the gut resistome'). Genes conferring resistance to antibiotics are ubiquitously present among the gut microbiota of humans and most resistance genes are harboured by strictly anaerobic gut commensals. The horizontal transfer of genetic material, including antibiotic resistance genes, through conjugation and transduction is a frequent event in the gut microbiota, but mostly involves non-pathogenic gut commensals as these dominate the microbiota of healthy individuals. Resistance gene transfer from commensals to gut-dwelling opportunistic pathogens appears to be a relatively rare event but may contribute to the emergence of multi-drug resistant strains, as is illustrated by the vancomycin resistance determinants that are shared by anaerobic gut commensals and the nosocomial pathogen Enterococcus faecium.

SUSY field theories in higher dimensions and integrable spin chains

International Nuclear Information System (INIS)

Gorsky, A.; Gukov, S.; Mironov, A.

1998-01-01

Five- and six-dimensional SUSY gauge theories, with one or two compactified directions, are discussed. The 5d theories with the matter hypermultiplets in the fundamental representation are associated with the twisted XXZ spin chain, while the group product case with bi-fundamental matter corresponds to the higher rank spin chains. The Riemann surfaces for 6d theories with fundamental matter and two compact directions are proposed to correspond to the XYZ spin chain based on the Sklyanin algebra. We also discuss the obtained results within the brane and geometrical engineering frameworks and explain the relation to the toric diagrams. (orig.)

GUTs and exceptional branes in F-theory - II. Experimental predictions

International Nuclear Information System (INIS)

Beasley, Chris; Heckman, Jonathan J.; Vafa, Cumrun

2009-01-01

We consider realizations of GUT models in F-theory. Adopting a bottom up approach, the assumption that the dynamics of the GUT model can in principle decouple from Planck scale physics leads to a surprisingly predictive framework. An internal U(1) hypercharge flux Higgses the GUT group directly to the MSSM or to a flipped GUT model, a mechanism unavailable in heterotic models. This new ingredient automatically addresses a number of puzzles present in traditional GUT models. The internal U(1) hyperflux allows us to solve the doublet-triplet splitting problem, and explains the qualitative features of the distorted GUT mass relations for lighter generations due to the Aharanov-Bohm effect. These models typically come with nearly exact global symmetries which prevent bare μ terms and also forbid dangerous baryon number violating operators. Strong curvature around our brane leads to a repulsion mechanism for Landau wave functions for neutral fields. This leads to large hierarchies of the form exp(-c/ε 2γ ) where c and γ are order one parameters and ε ∼ α GUT -1 M GUT /M pl . This effect can simultaneously generate a viably small μ term as well as an acceptable Dirac neutrino mass on the order of 0.5 x 10 -2±0.5 eV. In another scenario, we find a modified seesaw mechanism which predicts that the light neutrinos have masses in the expected range while the Majorana mass term for the heavy neutrinos is ∼ 3 x 10 12±1.5 GeV. Communicating supersymmetry breaking to the MSSM can be elegantly realized through gauge mediation. In one scenario, the same repulsion mechanism also leads to messenger masses which are naturally much lighter than the GUT scale.

Gut microbiota’s effect on mental health: The gut-brain axis

Directory of Open Access Journals (Sweden)

Megan Clapp

2017-09-01

Full Text Available The bidirectional communication between the central nervous system and gut microbiota, referred to as the gut-brain-axis, has been of significant interest in recent years. Increasing evidence has associated gut microbiota to both gastrointestinal and extragastrointestinal diseases. Dysbiosis and inflammation of the gut have been linked to causing several mental illnesses including anxiety and depression, which are prevalent in society today. Probiotics have the ability to restore normal microbial balance, and therefore have a potential role in the treatment and prevention of anxiety and depression. This review aims to discuss the development of the gut microbiota, the linkage of dysbiosis to anxiety and depression, and possible applications of probiotics to reduce symptoms.

Top-down approach to unified supergravity models

International Nuclear Information System (INIS)

Hempfling, R.

1994-03-01

We introduce a new approach for studying unified supergravity models. In this approach all the parameters of the grand unified theory (GUT) are fixed by imposing the corresponding number of low energy observables. This determines the remaining particle spectrum whose dependence on the low energy observables can now be investigated. We also include some SUSY threshold corrections that have previously been neglected. In particular the SUSY threshold corrections to the fermion masses can have a significant impact on the Yukawa coupling unification. (orig.)

Tail gut cyst.

Science.gov (United States)

Rao, G Mallikarjuna; Haricharan, P; Ramanujacharyulu, S; Reddy, K Lakshmi

2002-01-01

The tail gut is a blind extension of the hindgut into the tail fold just distal to the cloacal membrane. Remnants of this structure may form tail gut cyst. We report a 14-year-old girl with tail gut cyst that presented as acute abdomen. The patient recovered after cyst excision.

Beyond gut feelings: how the gut microbiota regulates blood pressure.

Science.gov (United States)

Marques, Francine Z; Mackay, Charles R; Kaye, David M

2018-01-01

Hypertension is the leading risk factor for heart disease and stroke, and is estimated to cause 9.4 million deaths globally every year. The pathogenesis of hypertension is complex, but lifestyle factors such as diet are important contributors to the disease. High dietary intake of fruit and vegetables is associated with reduced blood pressure and lower cardiovascular mortality. A critical relationship between dietary intake and the composition of the gut microbiota has been described in the literature, and a growing body of evidence supports the role of the gut microbiota in the regulation of blood pressure. In this Review, we describe the mechanisms by which the gut microbiota and its metabolites, including short-chain fatty acids, trimethylamine N-oxide, and lipopolysaccharides, act on downstream cellular targets to prevent or contribute to the pathogenesis of hypertension. These effects have a direct influence on tissues such as the kidney, the endothelium, and the heart. Finally, we consider the role of the gut microbiota in resistant hypertension, the possible intergenerational effect of the gut microbiota on blood pressure regulation, and the promising therapeutic potential of gut microbiota modification to improve health and prevent disease.

Dendritic cells in oral tolerance in the gut.

Science.gov (United States)

Rescigno, Maria

2011-09-01

Oral tolerance is a process that allows generation of systemic unresponsiveness to food antigens. Hence if the same antigen is introduced systemically even under immunogenic conditions it does not induce immune responsiveness. Dendritic cells (DCs) have been identified as essential players in this process. DCs in the gut are located in a strategic position as they can interact directly with luminal antigens or indirectly after their transcytosis across epithelial cells. DCs can then migrate to associated lymphoid tissues to induce tolerance. Antigen presenting cells in the gut are specialized in function and have divided their labour so that there are cells capable to migrate to the draining mesenteric lymph node for induction of T regulatory cells, while other subsets are resident and are required to enforce tolerance locally in the gut after food antigen exposure. In this review, I shall summarize the characteristics of antigen presenting cells in the gut and their involvement in oral tolerance induction. In addition, I will also emphasize that tolerance to food allergens may be contributed by plasmacytoid DCs in the liver that participate to the elimination or anergy of allergen-specific CD8 T cells. Hence specialized functions are associated to different subsets of antigen presenting cells and different organs. © 2011 Blackwell Publishing Ltd.

Gut metabolome meets microbiome

DEFF Research Database (Denmark)

Lamichhane, Santosh; Sen, Partho; Dickens, Alex M

2018-01-01

It is well established that gut microbes and their metabolic products regulate host metabolism. The interactions between the host and its gut microbiota are highly dynamic and complex. In this review we present and discuss the metabolomic strategies to study the gut microbial ecosystem. We...... highlight the metabolic profiling approaches to study faecal samples aimed at deciphering the metabolic product derived from gut microbiota. We also discuss how metabolomics data can be integrated with metagenomics data derived from gut microbiota and how such approaches may lead to better understanding...

Metabolomic insights into the intricate gut microbial–host interaction in the development of obesity and type 2 diabetes

Directory of Open Access Journals (Sweden)

Magali ePalau-Rodriguez

2015-10-01

Full Text Available Gut microbiota has recently been proposed as a crucial environmental factor in the development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its contribution in the modulation of several processes including host energy metabolism, gut epithelial permeability, gut peptide hormone secretion and host inflammatory state. Since the symbiotic interaction between the gut microbiota and the host is essentially reflected in specific metabolic signatures, much expectation is placed on the application of metabolomic approaches to unveil the key mechanisms linking the gut microbiota composition and activity with disease development. The present review aims to summarize the gut microbial-host co-metabolites identified so far by targeted and untargeted metabolomic studies in humans, in association with impaired glucose homeostasis and/or obesity. An alteration of the co-metabolism of bile acids, branched fatty acids, choline, vitamins (i.e. niacin, purines and phenolic compounds has been associated so far with the obese or diabese phenotype, in respect to healthy controls. Furthermore, anti-diabetic treatments such as metformin and sulfonylurea have been observed to modulate the gut microbiota or at least their metabolic profiles, thereby potentially affecting insulin resistance through indirect mechanisms still unknown. Despite the scarcity of the metabolomic studies currently available on the microbial-host crosstalk, the data-driven results largely confirmed findings independently obtained from in vitro and animal model studies, putting forward the mechanisms underlying the implication of a dysfunctional gut microbiota in the development of metabolic disorders.

Yukawa couplings in SO(10) heterotic M-theory vacua

International Nuclear Information System (INIS)

Faraggi, Alon E.; Garavuso, Richard S.

2003-01-01

We demonstrate the existence of a class of N=1 supersymmetric nonperturbative vacua of Horava-Witten M-theory compactified on a torus fibered Calabi-Yau 3-fold Z with first homotopy group π 1 (Z)=Z 2 , having the following properties: (1) SO(10) grand unification group, (2) net number of three generations of chiral fermions in the observable sector, and (3) potentially viable matter Yukawa couplings. These vacua correspond to semistable holomorphic vector bundles V Z over Z having structure group SU(4) C , and generically contain M5-branes in the bulk space. The nontrivial first homotopy group allows Wilson line breaking of the SO(10) symmetry. Additionally, we propose how the 11-dimensional Horava-Witten M-theory framework may be used to extend the perturbative calculation of the top quark Yukawa coupling in the realistic free-fermionic models to the nonperturbative regime. The basic argument being that the relevant coupling couples twisted-twisted-untwisted states and can be calculated at the level of the Z 2 xZ 2 orbifold without resorting to the full three generation models

Order and anarchy hand in hand in 5D SO(10)

International Nuclear Information System (INIS)

Vicino, D

2015-01-01

A mechanism to generate flavour hierarchy via 5D wave-function localization is revisited in the context of SO(10) grand unified theory. In an extra-dimension compactified on an orbifold, fermions (living in the same 16 representation of SO(10)) result having exponential zero-modes profiles, localized around one of the brane. The breaking of SO(10) down to SU(5) × U(1) x provides the key parameter that distinguishes the profiles of the different SU(5) components inside the same 16 representation. Utilizing a suitable set of scalar fields, a predictive model for fermion masses and mixing is constructed and shown to be viable with the current data through a detailed numerical analysis. The scalar field content of the model is also suitable to solve the doublet-triplet splitting problem through the missing partner mechanism. All the Yukawa couplings in the model are anarchical and of order unity, while the hierarchies among different fermions result only from zero-mode profiles. The naturalness of Anarchical Yukawa couplings is studied, showing a preference for a normal ordered neutrino spectrum; predictions for various observables in the lepton sector are also derived. (paper)

Diet, gut microbiota and cognition.

Science.gov (United States)

Proctor, Cicely; Thiennimitr, Parameth; Chattipakorn, Nipon; Chattipakorn, Siriporn C

2017-02-01

The consumption of a diet high in fat and sugar can lead to the development of obesity, type 2 diabetes mellitus (T2DM), cardiovascular disease and cognitive decline. In the human gut, the trillions of harmless microorganisms harboured in the host's gastrointestinal tract are called the 'gut microbiota'. Consumption of a diet high in fat and sugar changes the healthy microbiota composition which leads to an imbalanced microbial population in the gut, a phenomenon known as "gut dysbiosis". It has been shown that certain types of gut microbiota are linked to the pathogenesis of obesity. In addition, long-term consumption of a high fat diet is associated with cognitive decline. It has recently been proposed that the gut microbiota is part of a mechanistic link between the consumption of a high fat diet and the impaired cognition of an individual, termed "microbiota-gut-brain axis". In this complex relationship between the gut, the brain and the gut microbiota, there are several types of gut microbiota and host mechanisms involved. Most of these mechanisms are still poorly understood. Therefore, this review comprehensively summarizes the current evidence from mainly in vivo (rodent and human) studies of the relationship between diet, gut microbiota and cognition. The possible mechanisms that the diet and the gut microbiota have on cognition are also presented and discussed.

Searching for the standard model in the string landscape: SUSY GUTs

Science.gov (United States)

Raby, Stuart

2011-03-01

The standard model is the theory describing all observational data from the highest energies to the largest distances. (There is, however, one caveat: additional forms of energy, not part of the standard model, known as dark matter and dark energy must be included in order to describe the Universe at galactic scales and larger.) High energies refers to physics at the highest energy particle accelerators, including CERN's LEP II (which ceased operation in 2000 to begin construction of the Large Hadron Collider now in operation) and Fermilab's Tevatron, as well as to the energies obtained in particle jets created in so-called active galactic nuclei scattered throughout the visible Universe. Some of these extra-galactic particles bombard our own Earth in the form of cosmic rays, or super-energetic protons which scatter off nucei in the upper atmosphere. String theory is, on the other hand, an unfinished theoretical construct which attempts to describe all matter and their interactions in terms of the harmonic oscillations of open and/or closed strings. It is regarded as unfinished since at present it is a collection of ideas, tied together by powerful consistency conditions, called dualities, with the ultimate goal of finding the completed string theory. At the moment we only have descriptions which are valid in different mutually exclusive limits with names such as type I, IIA, IIB, heterotic, M and F theory. The string landscape has been described in the pages of many scholarly and popular works. It is perhaps best understood as the collection of possible solutions to the string equations; albeit these solutions look totally different in the different limiting descriptions. What do we know about the string landscape? We know that there are such a large number of possible solutions that the only way to represent this number is as 10500 or a 1 followed by 500 zeros. Note that this is not a precise value since the uncertainty is given by a number just as large

Effects of dietary amines on the gut and its vasculature.

Science.gov (United States)

Broadley, Kenneth J; Akhtar Anwar, M; Herbert, Amy A; Fehler, Martina; Jones, Elen M; Davies, Wyn E; Kidd, Emma J; Ford, William R

2009-06-01

Trace amines, including tyramine and beta-phenylethylamine (beta-PEA), are constituents of many foods including chocolate, cheeses and wines and are generated by so-called 'friendly' bacteria such as Lactobacillus, Lactococcus and Enterococcus species, which are found in probiotics. We therefore examined whether these dietary amines could exert pharmacological effects on the gut and its vasculature. In the present study we examined the effects of tyramine and beta-PEA on the contractile activity of guinea-pig and rat ileum and upon the isolated mesenteric vasculature and other blood vessels. Traditionally, these amines are regarded as sympathomimetic amines, exerting effects through the release of noradrenaline from sympathetic nerve endings, which should relax the gut. A secondary aim was therefore to confirm this mechanism of action. However, contractile effects were observed in the gut and these were independent of noradrenaline, acetylcholine, histamine and serotonin receptors. They were therefore probably due to the recently described trace amine-associated receptors. These amines relaxed the mesenteric vasculature. In contrast, the aorta and coronary arteries were constricted, a response that was also independent of a sympathomimetic action. From these results, we propose that after ingestion, trace amines could stimulate the gut and improve intestinal blood flow. Restriction of blood flow elsewhere diverts blood to the gut to aid digestion. Thus, trace amines in the diet may promote the digestive process through stimulation of the gut and improved gastrointestinal circulation.

GUTs in type IIB orientifold compactifications

International Nuclear Information System (INIS)

Blumenhagen, Ralph; Braun, Volker; Grimm, Thomas W.; Weigand, Timo

2009-01-01

We systematically analyse globally consistent SU(5) GUT models on intersecting D7-branes in genuine Calabi-Yau orientifolds with O3- and O7-planes. Beyond the well-known tadpole and K-theory cancellation conditions there exist a number of additional subtle but quite restrictive constraints. For the realisation of SU(5) GUTs with gauge symmetry breaking via U(1) Y flux we present two classes of suitable Calabi-Yau manifolds defined via del Pezzo transitions of the elliptically fibred hypersurface P 1,1,1,6,9 [18] and of the Quintic P 1,1,1,1,1 [5], respectively. To define an orientifold projection we classify all involutions on del Pezzo surfaces. We work out the model building prospects of these geometries and present five globally consistent string GUT models in detail, including a 3-generation SU(5) model with no exotics whatsoever. We also realise other phenomenological features such as the 10105 H Yukawa coupling and comment on the possibility of moduli stabilisation, where we find an entire new set of so-called swiss-cheese type Calabi-Yau manifolds. It is expected that both the general constrained structure and the concrete models lift to F-theory vacua on compact Calabi-Yau fourfolds.

SUSY-hierarchy of one-dimensional reflectionless potentials

CERN Document Server

Maydanyuk, Sergei P

2004-01-01

A class of one-dimensional reflectionless potentials, an absolute transparency of which is concerned with their belonging to one SUSY-hierarchy with a constant potential, is studied. An approach for determination of a general form of the reflectionless potential on the basis of construction of such a hierarchy by the recurrent method is proposed. A general form of interdependence between superpotentials with neighboring numbers of this hierarchy, opening a possibility to find new reflectionless potentials, have a simple analytical view and are expressed through finite number of elementary functions (unlike some reflectionless potentials, which are constructed on the basis of soliton solutions or are shape invariant in one or many steps with involving scaling of parameters, and are expressed through series), is obtained. An analysis of absolute transparency existence for the potential which has the inverse power dependence on space coordinate (and here tunneling is possible), i.e. which has the form $V(x) = \\p...

High Energy Theory: Task B and Task L. Progress report

International Nuclear Information System (INIS)

1994-01-01

Research areas briefly covered in this report include semi-leptonic and non-leptonic B- and D-decays, CP violation, lattice gauge theory, light cone field theory, supersymmetry, fermion mass matrices, superstrings derived SUSY GUTs, neutrino physics and cosmology

Constrained Sypersymmetric Flipped SU (5) GUT Phenomenology

Energy Technology Data Exchange (ETDEWEB)

Ellis, John; /CERN /King' s Coll. London; Mustafayev, Azar; /Minnesota U., Theor. Phys. Inst.; Olive, Keith A.; /Minnesota U., Theor. Phys. Inst. /Minnesota U. /Stanford U., Phys. Dept. /SLAC

2011-08-12

We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, Min, above the GUT scale, M{sub GUT}. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino {chi} and the lighter stau {tilde {tau}}{sub 1} is sensitive to M{sub in}, as is the relationship between m{sub {chi}} and the masses of the heavier Higgs bosons A,H. For these reasons, prominent features in generic (m{sub 1/2}, m{sub 0}) planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to Min, as we illustrate for several cases with tan {beta} = 10 and 55. However, these features do not necessarily disappear at large Min, unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses.

Constrained supersymmetric flipped SU(5) GUT phenomenology

Energy Technology Data Exchange (ETDEWEB)

Ellis, John [CERN, TH Division, PH Department, Geneva 23 (Switzerland); King' s College London, Theoretical Physics and Cosmology Group, Department of Physics, London (United Kingdom); Mustafayev, Azar [University of Minnesota, William I. Fine Theoretical Physics Institute, Minneapolis, MN (United States); Olive, Keith A. [University of Minnesota, William I. Fine Theoretical Physics Institute, Minneapolis, MN (United States); Stanford University, Department of Physics and SLAC, Palo Alto, CA (United States)

2011-07-15

We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, M{sub in}, above the GUT scale, M{sub GUT}. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino {chi} and the lighter stau {tau}{sub 1} is sensitive to M{sub in}, as is the relationship between m{sub {chi}} and the masses of the heavier Higgs bosons A,H. For these reasons, prominent features in generic (m{sub 1/2},m{sub 0}) planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to M{sub in}, as we illustrate for several cases with tan {beta}=10 and 55. However, these features do not necessarily disappear at large M{sub in}, unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses. (orig.)

Constrained supersymmetric flipped SU(5) GUT phenomenology

International Nuclear Information System (INIS)

Ellis, John; Mustafayev, Azar; Olive, Keith A.

2011-01-01

We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, M in , above the GUT scale, M GUT . We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino χ and the lighter stau τ 1 is sensitive to M in , as is the relationship between m χ and the masses of the heavier Higgs bosons A,H. For these reasons, prominent features in generic (m 1/2 ,m 0 ) planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to M in , as we illustrate for several cases with tan β=10 and 55. However, these features do not necessarily disappear at large M in , unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses. (orig.)

The diagnosis and treatment of non-occlusive gut ischaemia

International Nuclear Information System (INIS)

Schindler, G.; Bruch, H.P.; Wuerzburg Univ.

1991-01-01

Non-occlusive gut ischaemia is a disease of advanced age. Its causes are reduced cardiac output or shock, facilitated by digitalis, adrenaline, ergotamine and diuretics. The persisting microcirculation and development of gut necrois leads to an increase in certain serum enzymes, such as lactate, LDH and CK-NB. The early application of mesenteric angiography using a DSA technique reveals four grades of under-perfusion. Early and correct diagnosis of the disease should lead to intra-arterial treatment with prostaglandin. In 10 out of 42 cases, conservative therapy led to re-perfusion of the gut. (orig.) [de

Diet shapes the gut microbiota of the omnivorous cockroach Blattella germanica.

Science.gov (United States)

Pérez-Cobas, Ana Elena; Maiques, Elisa; Angelova, Alexandra; Carrasco, Purificación; Moya, Andrés; Latorre, Amparo

2015-04-01

The gut microbiota of insects contributes positively to the physiology of its host mainly by participating in food digestion, protecting against pathogens, or provisioning vitamins or amino acids, but the dynamics of this complex ecosystem is not well understood so far. In this study, we have characterized the gut microbiota of the omnivorous cockroach Blattella germanica by pyrosequencing the hypervariable regions V1-V3 of the 16S rRNA gene of the whole bacterial community. Three diets differing in the protein content (0, 24 and 50%) were tested at two time points in lab-reared individuals. In addition, the gut microbiota of wild adult cockroaches was also analyzed. In contrast to the high microbial richness described on the studied samples, only few species are shared by wild and lab-reared cockroaches, constituting the bacterial core in the gut of B. germanica. Overall, we found that the gut microbiota of B. germanica is highly dynamic as the bacterial composition was reassembled in a diet-specific manner over a short time span, with no-protein diet promoting high diversity, although the highest diversity was found in the wild cockroaches analyzed. We discuss how the flexibility of the gut microbiota is probably due to its omnivorous life style and varied diets. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Comparative metagenomic analysis of plasmid encoded functions in the human gut microbiome

Directory of Open Access Journals (Sweden)

Marchesi Julian R

2010-01-01

Full Text Available Abstract Background Little is known regarding the pool of mobile genetic elements associated with the human gut microbiome. In this study we employed the culture independent TRACA system to isolate novel plasmids from the human gut microbiota, and a comparative metagenomic analysis to investigate the distribution and relative abundance of functions encoded by these plasmids in the human gut microbiome. Results Novel plasmids were acquired from the human gut microbiome, and homologous nucleotide sequences with high identity (>90% to two plasmids (pTRACA10 and pTRACA22 were identified in the multiple human gut microbiomes analysed here. However, no homologous nucleotide sequences to these plasmids were identified in the murine gut or environmental metagenomes. Functions encoded by the plasmids pTRACA10 and pTRACA22 were found to be more prevalent in the human gut microbiome when compared to microbial communities from other environments. Among the most prevalent functions identified was a putative RelBE toxin-antitoxin (TA addiction module, and subsequent analysis revealed that this was most closely related to putative TA modules from gut associated bacteria belonging to the Firmicutes. A broad phylogenetic distribution of RelE toxin genes was observed in gut associated bacterial species (Firmicutes, Bacteroidetes, Actinobacteria and Proteobacteria, but no RelE homologues were identified in gut associated archaeal species. We also provide indirect evidence for the horizontal transfer of these genes between bacterial species belonging to disparate phylogenetic divisions, namely Gram negative Proteobacteria and Gram positive species from the Firmicutes division. Conclusions The application of a culture independent system to capture novel plasmids from the human gut mobile metagenome, coupled with subsequent comparative metagenomic analysis, highlighted the unexpected prevalence of plasmid encoded functions in the gut microbial ecosystem. In

Gut Protozoa: Friends or Foes of the Human Gut Microbiota?

Science.gov (United States)

Chabé, Magali; Lokmer, Ana; Ségurel, Laure

2017-12-01

The importance of the gut microbiota for human health has sparked a strong interest in the study of the factors that shape its composition and diversity. Despite the growing evidence suggesting that helminths and protozoa significantly interact with gut bacteria, gut microbiome studies remain mostly focused on prokaryotes and on populations living in industrialized countries that typically have a low parasite burden. We argue that protozoa, like helminths, represent an important factor to take into account when studying the gut microbiome, and that their presence - especially considering their long coevolutionary history with humans - may be beneficial. From this perspective, we examine the relationship between the protozoa and their hosts, as well as their relevance for public health. Copyright © 2017 Elsevier Ltd. All rights reserved.

Cosmological implications of a class of SO(10) models

International Nuclear Information System (INIS)

Mangano, G.; Rosa, L.

1996-01-01

The cosmological implications of a class of SO(10) models are discussed. In particular we show how a good prediction for neutrino masses is obtained in order to fit with the MSW mechanism to explain the solar neutrino flux deficit and with the predicted amount of the dark matter hot component. A possible scenario for baryogenesis is also considered. (orig.)

Towards realistic D=6, N=2 Kaluza-Klein supergravity on coset E7/SO(12)xSp(1) with chiral fermions

International Nuclear Information System (INIS)

Koh, I.G.; Nishino, H.

1984-08-01

An SO(10) GUT model with realistic left-handed chiral 16sub(tilde) fermions is obtained from the D=6, N=2 supergravity with matter and gauge couplings on the scalar coset E 7 /SO(12)xSp(1). The six dimensions compactify into (four-dimensional Minkowski space-time) x (two sphere S 2 ) by a monopole on S 2 without any fine-tuning for the four-dimensional cosmological constant. The monopole charge n (when positive) directly gives the number of generations of quarks and leptons. (author)

Gut microbiota and obesity.

Science.gov (United States)

Gérard, Philippe

2016-01-01

The human intestine harbors a complex bacterial community called the gut microbiota. This microbiota is specific to each individual despite the existence of several bacterial species shared by the majority of adults. The influence of the gut microbiota in human health and disease has been revealed in the recent years. Particularly, the use of germ-free animals and microbiota transplant showed that the gut microbiota may play a causal role in the development of obesity and associated metabolic disorders, and lead to identification of several mechanisms. In humans, differences in microbiota composition, functional genes and metabolic activities are observed between obese and lean individuals suggesting a contribution of the gut microbiota to these phenotypes. Finally, the evidence linking gut bacteria to host metabolism could allow the development of new therapeutic strategies based on gut microbiota modulation to treat or prevent obesity.

SUSY-QCD corrections to the (co)annihilation of neutralino dark matter within the MSSM

Energy Technology Data Exchange (ETDEWEB)

Meinecke, Moritz

2015-06-15

Based on experimental observations, it is nowadays assumed that a large component of the matter content in the universe is comprised of so-called cold dark matter. Furthermore, latest measurements of the temperature fluctuations of the cosmic microwave background provided an estimation of the dark matter relic density at a measurement error of one percent (concerning the experimental 1σ-error). The lightest neutralino χ 0{sub 1}, a particle which subsumes under the phenomenologically interesting category of weakly interacting massive particles, is a viable dark matter candidate for many supersymmetric (SUSY) models whose relic density Ω{sub χ} {sub 0{sub 1}} happens to lie quite naturally within the experimentally favored ballpark of dark matter. The high experimental precision can be used to constrain the SUSY parameter space to its cosmologically favored regions and to pin down phenomenologically interesting scenarios. However, to actually benefit from this progress on the experimental side it is also mandatory to minimize the theoretical uncertainties. An important quantity within the calculation of the neutralino relic density is the thermally averaged sum over different annihilation and coannihilation cross sections of the neutralino and further supersymmetric particles. It is now assumed and also partly proven that these cross sections can be subject to large loop corrections which can even shift the associated Ω{sub χ} {sub 0{sub 1}} by a factor larger than the current experimental error. However, most of these corrections are yet unknown. In this thesis, we calculate higher-order corrections for some of the most important (co)annihilation channels both within the framework of the R-parity conserving Minimal Supersymmetric Standard Model (MSSM) and investigate their impact on the final neutralino relic density Ω{sub χ} {sub 0{sub 1}}. More precisely, this work provides the full O(α{sub s}) corrections of supersymmetric quantum chromodynamics (SUSY

Dynamical symmetry breakdown in SU(5) and SO(10)

International Nuclear Information System (INIS)

Shellard, R.C.

1983-09-01

Some restrictions imposed upon Grand Unified Theories by dynamical symmetry breakdown are examined. It is observed in particular, that theories with SU(5) as symmetry group, with 3 or more fermion families undergo dynamical symmetry breakdown, and some of the fermions will acquire mass at the Grand Unified scale. On the other hand, the SO(10) group, with 3 families is free from this problem. (Author) [pt

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis

Energy Technology Data Exchange (ETDEWEB)

Goto, Tsuyoshi, E-mail: tgoto@kais.kyoto-u.ac.jp [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Research Unit for Physiological Chemistry, The Center for the Promotion of Interdisciplinary Education and Research, Kyoto University (Japan); Kim, Young-Il; Furuzono, Tomoya [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Takahashi, Nobuyuki [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Research Unit for Physiological Chemistry, The Center for the Promotion of Interdisciplinary Education and Research, Kyoto University (Japan); Yamakuni, Kanae; Yang, Ha-Eun; Li, Yongjia [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Ohue, Ryuji [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Research Unit for Physiological Chemistry, The Center for the Promotion of Interdisciplinary Education and Research, Kyoto University (Japan); Nomura, Wataru [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Sugawara, Tatsuya [Laboratory of Marine Bioproducts Technology, Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502 (Japan); Yu, Rina [Department of Food Science and Nutrition, University of Ulsan, Ulsan 680-749 (Korea, Republic of); Kitamura, Nahoko [Laboratory of Fermentation Physiology and Applied Microbiology, Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502 (Japan); and others

2015-04-17

Our previous study has shown that gut lactic acid bacteria generate various kinds of fatty acids from polyunsaturated fatty acids such as linoleic acid (LA). In this study, we investigated the effects of LA and LA-derived fatty acids on the activation of peroxisome proliferator-activated receptors (PPARs) which regulate whole-body energy metabolism. None of the fatty acids activated PPARδ, whereas almost all activated PPARα in luciferase assays. Two fatty acids potently activated PPARγ, a master regulator of adipocyte differentiation, with 10-oxo-12(Z)-octadecenoic acid (KetoA) having the most potency. In 3T3-L1 cells, KetoA induced adipocyte differentiation via the activation of PPARγ, and increased adiponectin production and insulin-stimulated glucose uptake. These findings suggest that fatty acids, including KetoA, generated in gut by lactic acid bacteria may be involved in the regulation of host energy metabolism. - Highlights: • Most LA-derived fatty acids from gut lactic acid bacteria potently activated PPARα. • Among tested fatty acids, KetoA and KetoC significantly activated PPARγ. • KetoA induced adipocyte differentiation via the activation of PPARγ. • KetoA enhanced adiponectin production and glucose uptake during adipogenesis.

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis

International Nuclear Information System (INIS)

Goto, Tsuyoshi; Kim, Young-Il; Furuzono, Tomoya; Takahashi, Nobuyuki; Yamakuni, Kanae; Yang, Ha-Eun; Li, Yongjia; Ohue, Ryuji; Nomura, Wataru; Sugawara, Tatsuya; Yu, Rina; Kitamura, Nahoko

2015-01-01

Our previous study has shown that gut lactic acid bacteria generate various kinds of fatty acids from polyunsaturated fatty acids such as linoleic acid (LA). In this study, we investigated the effects of LA and LA-derived fatty acids on the activation of peroxisome proliferator-activated receptors (PPARs) which regulate whole-body energy metabolism. None of the fatty acids activated PPARδ, whereas almost all activated PPARα in luciferase assays. Two fatty acids potently activated PPARγ, a master regulator of adipocyte differentiation, with 10-oxo-12(Z)-octadecenoic acid (KetoA) having the most potency. In 3T3-L1 cells, KetoA induced adipocyte differentiation via the activation of PPARγ, and increased adiponectin production and insulin-stimulated glucose uptake. These findings suggest that fatty acids, including KetoA, generated in gut by lactic acid bacteria may be involved in the regulation of host energy metabolism. - Highlights: • Most LA-derived fatty acids from gut lactic acid bacteria potently activated PPARα. • Among tested fatty acids, KetoA and KetoC significantly activated PPARγ. • KetoA induced adipocyte differentiation via the activation of PPARγ. • KetoA enhanced adiponectin production and glucose uptake during adipogenesis

Flipped version of the supersymmetric strongly coupled preon model

Energy Technology Data Exchange (ETDEWEB)

Fajfer, S. (Institut za Fiziku, University of Sarajevo, Sarajevo, (Yugoslavia)); Milekovic, M.; Tadic, D. (Zavod za Teorijsku Fiziku, Prirodoslovno-Matematicki Fakultet, University of Zagreb, Croatia, (Yugoslavia))

1989-12-01

In the supersymmetric SU(5) (SUSY SU(5)) composite model (which was described in an earlier paper) the fermion mass terms can be easily constructed. The SUSY SU(5){direct product}U(1), i.e., flipped, composite model possesses a completely analogous composite-particle spectrum. However, in that model one cannot construct a renormalizable superpotential which would generate fermion mass terms. This contrasts with the standard noncomposite grand unified theories (GUT's) in which both the Georgi-Glashow electrical charge embedding and its flipped counterpart lead to the renormalizable theories.

SO(10) supersymmetric grand unified theories

Science.gov (United States)

Dermisek, Radovan

The origin of the fermion mass hierarchy is one of the most challenging problems in elementary particle physics. In the standard model fermion masses and mixing angles are free parameters. Supersymmetric grand unified theories provide a beautiful framework for physics beyond the standard model. In addition to gauge coupling unification these theories provide relations between quark and lepton masses within families, and with additional family symmetry the hierarchy between families can be generated. We present a predictive SO(10) supersymmetric grand unified model with D 3 x U(1) family symmetry. The hierarchy in fermion masses is generated by the family symmetry breaking D 3 x U(1) → ZN → nothing. This model fits the low energy data in the charged fermion sector quite well. We discuss the prediction of this model for the proton lifetime in light of recent SuperKamiokande results and present a clear picture of the allowed spectra of supersymmetric particles. Finally, the detailed discussion of the Yukawa coupling unification of the third generation particles is provided. We find a narrow region is consistent with t, b, tau Yukawa unification for mu > 0 (suggested by b → sgamma and the anomalous magnetic moment of the muon) with A0 ˜ -1.9m16, m10 ˜ 1.4m16, m16 ≳ 1200 GeV and mu, M1/2 ˜ 100--500 GeV. Demanding Yukawa unification thus makes definite predictions for Higgs and sparticle masses.

One-loop stabilization of the fuzzy four-sphere via softly broken SUSY

Energy Technology Data Exchange (ETDEWEB)

Steinacker, Harold C. [Faculty of Physics, University of Vienna,Boltzmanngasse 5, A-1090 Vienna (Austria)

2015-12-17

We describe a stabilization mechanism for fuzzy S{sub N}{sup 4} in the Euclidean IIB matrix model due to vacuum energy in the presence of a positive mass term. The one-loop effective potential for the radius contains an attractive contribution attributed to supergravity, while the mass term induces a repulsive contribution for small radius due to SUSY breaking. This leads to a stabilization of the radius. The mechanism should be pertinent to recent results on the genesis of 3+1-dimensional space-time in the Minkowskian IIB model.

Testing SUSY at the LHC: Electroweak and Dark matter fine tuning at two-loop order

CERN Document Server

Cassel, S; Ross, G G

2010-01-01

In the framework of the Constrained Minimal Supersymmetric Standard Model (CMSSM) we evaluate the electroweak fine tuning measure that provides a quantitative test of supersymmetry as a solution to the hierarchy problem. Taking account of current experimental constraints we compute the fine tuning at two-loop order and determine the limits on the CMSSM parameter space and the measurements at the LHC most relevant in covering it. Without imposing the LEPII bound on the Higgs mass, it is shown that the fine tuning computed at two-loop has a minimum $\\Delta=8.8$ corresponding to a Higgs mass $m_h=114\\pm 2$ GeV. Adding the constraint that the SUSY dark matter relic density should be within present bounds we find $\\Delta=15$ corresponding to $m_h=114.7\\pm 2$ GeV and this rises to $\\Delta=17.8$ ($m_h=115.9\\pm 2$ GeV) for SUSY dark matter abundance within 3$\\sigma$ of the WMAP constraint. We extend the analysis to include the contribution of dark matter fine tuning. In this case the overall fine tuning and Higgs mas...

The "Gut Feeling": Breaking Down the Role of Gut Microbiome in Multiple Sclerosis.

Science.gov (United States)

Freedman, Samantha N; Shahi, Shailesh K; Mangalam, Ashutosh K

2018-01-01

Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system with unknown etiology. Recently, the gut microbiota has emerged as a potential factor in the development of MS, with a number of studies having shown that patients with MS exhibit gut dysbiosis. The gut microbiota helps the host remain healthy by regulating various functions, including food metabolism, energy homeostasis, maintenance of the intestinal barrier, inhibition of colonization by pathogenic organisms, and shaping of both mucosal and systemic immune responses. Alteration of the gut microbiota, and subsequent changes in its metabolic network that perturb this homeostasis, may lead to intestinal and systemic disorders such as MS. Here we discuss the findings of recent MS microbiome studies and potential mechanisms through which gut microbiota can predispose to, or protect against, MS. These findings highlight the need of an improved understanding of the interactions between the microbiota and host for developing therapies based on gut commensals with which to treat MS.

Gut microbiome and bone.

Science.gov (United States)

Ibáñez, Lidia; Rouleau, Matthieu; Wakkach, Abdelilah; Blin-Wakkach, Claudine

2018-04-11

The gut microbiome is now viewed as a tissue that interacts bidirectionally with the gastrointestinal, immune, endocrine and nervous systems, affecting the cellular responses in numerous organs. Evidence is accumulating of gut microbiome involvement in a growing number of pathophysiological processes, many of which are linked to inflammatory responses. More specifically, data acquired over the last decade point to effects of the gut microbiome on bone mass regulation and on the development of bone diseases (such as osteoporosis) and of inflammatory joint diseases characterized by bone loss. Mice lacking a gut microbiome have bone mass alteration that can be reversed by gut recolonization. Changes in the gut microbiome composition have been reported in mice with estrogen-deficiency osteoporosis and have also been found in a few studies in humans. Probiotic therapy decreases bone loss in estrogen-deficient animals. The effect of the gut microbiome on bone tissue involves complex mechanisms including modulation of CD4 + T cell activation, control of osteoclastogenic cytokine production and modifications in hormone levels. This complexity may contribute to explain the discrepancies observed betwwen some studies whose results vary depending on the age, gender, genetic background and treatment duration. Further elucidation of the mechanisms involved is needed. However, the available data hold promise that gut microbiome manipulation may prove of interest in the management of bone diseases. Copyright © 2018 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

Mart Susi müüb Concordia ülikooli hüvanguks Kolu mõisa / Sigrid Laev

Index Scriptorium Estoniae

Laev, Sigrid

2003-01-01

Concordia ülikooli rektor Mart Susi pani müüki endale kuuluva Kolu mõisa, et sellest saadava rahaga katta ülikooli vajadusi. Tallinna Pedagoogikaülikool on Concordia ostmisest huvitatud. Concordia ülikooli tudengid on teinud üleskutse ühinemiseks, et kooli tuleviku suhtes kaasa rääkida

Radiation and Gut

International Nuclear Information System (INIS)

Potten, C.S.; Hendry, J.H.

1995-08-01

Texts on gut with reference to radiation (or other cytotoxic and carcinogenic agents) consist of primary research papers, review articles, or books which are now very out-of-date. With this in mind, the present book was conceived. Here, with chapters by experts in the field, we cover the basic structure and cell replacement process in the gut, the physical situation relevant for gut radiation exposure and a description of some of the techniques used to study radiation effects, in particular the clonal regeneration assay that assesses stem cell functional capacity. Chapters comprehensively cover the effects of radiation in experimental animal model systems and clinical experiences. The effects of radiation on the supportive tissue of the gut is also reviewed. The special radiation situation involving ingested radionuclides is reviewed and the most important late response-carcinogenesis-within the gut is considered. This book follows a volume on 'Radiation and Skin' (1985) and another on 'Radiation and Bone Marrow' is in preparation. The present volume is intended to cover the anatomy and renewal characteristics of the gut, and its response in terms of carcinogenicity and tissue injury in mammalian species including in particular man. The book is expected to be useful to students and teachers in these topics, as well as clinical oncologists (radiotherapists) and medical oncologists, and industrial health personnel. 70 figs., 20 tabs., 869 refs

Comparative gut physiology symposium: The microbe-gut-brain axis

Science.gov (United States)

The Comparative Gut Physiology Symposium titled “The Microbe-Gut-Brain Axis” was held at the Joint Annual Meeting of the American Society of Animal Science and the American Dairy Science Association on Thursday, July 21, 2016, in Salt Lake City Utah. The goal of the symposium was to present basic r...

Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

DEFF Research Database (Denmark)

Mikkelsen, Kristian H; Frost, Morten; Bahl, Martin Iain

2015-01-01

The gut microbiota has been designated as an active regulator of glucose metabolism and metabolic phenotype in a number of animal and human observational studies. We evaluated the effect of removing as many bacteria as possible by antibiotics on postprandial physiology in healthy humans. Meal tests...... tolerance, insulin secretion or plasma lipid concentrations were found. Apart from an acute and reversible increase in peptide YY secretion, no changes were observed in postprandial gut hormone release. As evaluated by selective cultivation of gut bacteria, a broad-spectrum 4-day antibiotics course...... with vancomycin, gentamycin and meropenem induced shifts in gut microbiota composition that had no clinically relevant short or long-term effects on metabolic variables in healthy glucose-tolerant males. clinicaltrials.gov NCT01633762....

Energy analysis of four dimensional extended hyperbolic Scarf I plus three dimensional separable trigonometric noncentral potentials using SUSY QM approach

International Nuclear Information System (INIS)

Suparmi, A.; Cari, C.; Deta, U. A.; Handhika, J.

2016-01-01

The non-relativistic energies and wave functions of extended hyperbolic Scarf I plus separable non-central shape invariant potential in four dimensions are investigated using Supersymmetric Quantum Mechanics (SUSY QM) Approach. The three dimensional separable non-central shape invariant angular potential consists of trigonometric Scarf II, Manning Rosen and Poschl-Teller potentials. The four dimensional Schrodinger equation with separable shape invariant non-central potential is reduced into four one dimensional Schrodinger equations through variable separation method. By using SUSY QM, the non-relativistic energies and radial wave functions are obtained from radial Schrodinger equation, the orbital quantum numbers and angular wave functions are obtained from angular Schrodinger equations. The extended potential means there is perturbation terms in potential and cause the decrease in energy spectra of Scarf I potential. (paper)

Early-life gut bacteria associate with IL-4-, IL-10- and IFN-γ production at two years of age.

Directory of Open Access Journals (Sweden)

Maria A Johansson

Full Text Available Microbial exposure early in life influences immune maturation and potentially also the development of immune-mediated disease. Here we studied early-life gut colonization in relation to cytokine responses at two years of age. Fecal samples were collected from infants during the first two months of life. DNA was extracted from the fecal samples and Bifidobacterium (B. adolescentis, B. breve, B. bifidum, a group of lactobacilli (L. casei, L. paracasei and L. rhamnosus as well as Staphylococcus (S. aureus were detected with real time PCR. Peripheral mononuclear cells were stimulated with phytohaemagglutinin (PHA and numbers of IL-4-, IL-10- and IFN-γ secreting cells were evaluated using ELISpot. We further stimulated peripheral blood mononuclear cells with bacterial supernatants in vitro and assessed the IL-4-, IL-10- and IFN-γ inducing capacity by flow cytometry and ELISA. Early S. aureus colonization associated with higher numbers of IL-4- (p = 0.022 and IL-10 (p = 0.016 producing cells at two years of age. In contrast to colonization with S. aureus alone, co-colonization with lactobacilli associated with suppression of IL-4- (p = 0.004, IL-10- (p = 0.004 and IFN-γ (p = 0.034 secreting cells. In vitro stimulations of mononuclear cells with bacterial supernatants supported a suppressive role of L. rhamnosus GG on S. aureus-induced cytokine responses. We demonstrate that the early gut colonization pattern associates with the PHA-induced cytokine profile at two years of age and our in vitro findings support that specific bacterial species influence the T helper cell subsets. This suggests that dysbiosis in the early microbiota may modulate the risk of developing inflammatory conditions like allergy.

Cyanide sulphur transferase from the gut and body segments of ...

African Journals Online (AJOL)

Our results show total rhodanese activities of 1434.50 RU and 2274.28 RU and specific activities of 108.01 RUmg-1 and 83.1901 RUmg-1 in the gut and body segments of H. africanus respectively. The optimum temperature of 25 °C and optimum pH of 10.5 were obtained for both the gut and body segments enzymes.

Supersimplicity: a Remarkable High Energy SUSY Property

International Nuclear Information System (INIS)

Gounaris, G.J.; Renard, F.M.

2011-01-01

It is known that for any 2-to-2 process in MSSM, only the helicity conserving (HC) amplitudes survive asymptotically. Studying many such processes, at the 1-loop Electroweak (EW) order, it is found that their high energy HC amplitudes are determined by just three forms: a log-squared function of the ratio of two of the (s, t, u) variables, to which a π 2 is added; and two Sudakov-like ln- and ln 2 -terms accompanied by respective mass-dependent constants. Apart from a possible additional residual constant (which is also discussed), these HC amplitudes, may be expressed as linear combinations of the above three forms, with coefficients being rational functions of the (s, t, u) variables. This 1-loop property, called supersimplicity, is of course claimed for the 2-to-2 processes considered; but no violating examples are known at present. For ug → dW, supersimplicity is found to be a very good approximation at LHC energies, provided the SUSY scale is not too high. SM processes are also discussed, and their differences are explored. (authors)

Gut microbiota and metabolic syndrome.

Science.gov (United States)

Festi, Davide; Schiumerini, Ramona; Eusebi, Leonardo Henry; Marasco, Giovanni; Taddia, Martina; Colecchia, Antonio

2014-11-21

Gut microbiota exerts a significant role in the pathogenesis of the metabolic syndrome, as confirmed by studies conducted both on humans and animal models. Gut microbial composition and functions are strongly influenced by diet. This complex intestinal "superorganism" seems to affect host metabolic balance modulating energy absorption, gut motility, appetite, glucose and lipid metabolism, as well as hepatic fatty storage. An impairment of the fine balance between gut microbes and host's immune system could culminate in the intestinal translocation of bacterial fragments and the development of "metabolic endotoxemia", leading to systemic inflammation and insulin resistance. Diet induced weight-loss and bariatric surgery promote significant changes of gut microbial composition, that seem to affect the success, or the inefficacy, of treatment strategies. Manipulation of gut microbiota through the administration of prebiotics or probiotics could reduce intestinal low grade inflammation and improve gut barrier integrity, thus, ameliorating metabolic balance and promoting weight loss. However, further evidence is needed to better understand their clinical impact and therapeutic use.

SUSY searches in events with two opposite-sign same-flavor leptons, jets and MET with the CMS detector

CERN Document Server

Schulte, Jan-Frederik

2017-01-01

Searches for Supersymmetry (SUSY) in events with two opposite-sign same-flavour leptons offer sensitivity to the production of sleptons or Z bosons in the cascade decays of initially produced heavy SUSY particles. In the considered models, this signature is accompanied by the presence of several jets and high missing transverse energy. Analysing their respective datasets recorded at √ s = 8 TeV, the ATLAS and CMS collaborations previously reported deviations from the pre- dicted Standard Model backgrounds in this final state, with significances between 2.6 and 3.0 σ . However, these excesses had been observed in different regions of the dilepton invariant mass. The dataset recorded with the CMS detector at √ s = 13 TeV in 2015, corresponding to 2.3 fb − 1 , offers the opportunity to substantiate or refute these interesting hints for new phenomena. Unfor- tunately, no significant deviation from the background estimates are observed in either of the two selections which had shown excesses in the √ s = ...

Lactobacillus paracasei HII01, xylooligosaccharides, and synbiotics reduce gut disturbance in obese rats.

Science.gov (United States)

Thiennimitr, Parameth; Yasom, Sakawdaurn; Tunapong, Wannipa; Chunchai, Titikorn; Wanchai, Keerati; Pongchaidecha, Anchalee; Lungkaphin, Anusorn; Sirilun, Sasithorn; Chaiyasut, Chaiyavat; Chattipakorn, Nipon; Chattipakorn, Siriporn C

2018-03-20

The beneficial effects of pro-, pre-, and synbiotics on obesity with insulin resistance have been reported previously. However, the strain-specific effect of probiotics and the combination with various types of prebiotic fiber yield controversial outcomes and limit clinical applications. Our previous study demonstrated that the probiotic Lactobacillus paracasei (L. paracasei) HII01, prebiotic xylooligosaccharide (XOS), and synbiotics share similar efficacy in attenuating cardiac mitochondrial dysfunction in obese-insulin resistant rats. Nonetheless, the roles of HII01 and XOS on gut dysbiosis and gut inflammation under obese-insulin resistant conditions have not yet, to our knowledge, been investigated. Our hypothesis was that pro-, pre-, and synbiotics improve the metabolic parameters in obese-insulin resistant rats by reducing gut dysbiosis and gut inflammation. Male Wistar rats were fed with either a normal or high-fat diet that contained 19.77% and 59.28% energy from fat, respectively, for 12 wk. Then, the high-fat diet rats were fed daily with a 10 8 colony forming unit of the probiotic HII01, 10% prebiotic XOS, and synbiotics for 12 wk. The metabolic parameters, serum lipopolysaccharide levels, fecal Firmicutes/Bacteroidetes ratios, levels of Enterobacteriaceae, Bifidobacteria, and gut proinflammatory cytokine gene expression were quantified. The consumption of probiotic L. paracasei HII01, prebiotic XOS, and synbiotics for 12 wk led to a decrease in metabolic endotoxemia, gut dysbiosis (a reduction in the Firmicutes/Bacteroidetes ratio and Enterobacteriaceae), and gut inflammation in obese-insulin resistant rats. Pro-, pre-, and synbiotics reduced gut dysbiosis and gut inflammation, which lead to improvements in metabolic dysfunction in obese-insulin resistant rats. Copyright © 2018 Elsevier Inc. All rights reserved.

Gut Microbiota and Body Weight – A Review

Directory of Open Access Journals (Sweden)

Ioana Duca

2018-05-01

Full Text Available The link between gut microbiota and insulin resistance has an important clinical impact, people affected by dysbiosis having a predisposition for developing: obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, cancers, cardiovascular, neurodegenerative and psychiatric diseases. Dysbiosis may lead through chronic inflammation to obesity and metabolic syndrome. We carried out a systematic review of the studies dedicated to the role of gut microbiota in weight gain and obesity. A systematic literature search of recent data published in electronic databases, was performed, using as search phrase: "gut microbiome and body weight and obesity". Studies that contained no data about the influence of gut microbiota changes on obesity were excluded. Western diet, antibiotic use in childhood, excessive maternal pre-pregnancy weight, Cesarean delivery, and testosterone deficiency are triggers of the alteration of microbiota and subsequently the appearance of obesity. Predominance of Firmicutes and anaerobic genera, changes in the mycobiome and viral intestinal population are implied in the etiology of obesity. Prebiotics, polyphenols, different herbs, medication (antidiabetics, calcium, physical exercise, rich fibre intake and bariatric surgery are the most important therapeutic options. Personalized dietary treatments, antiviral agents and mycobiome manipulation would represent the new target in treating obesity. Any change of the quantitative and qualitative composition of microbiota has influence on the components of metabolic syndrome, so any management strategy for the treatment or prevention of obesity in children and adulthood should have the microbiome as target.

Electron and muon electric dipoles in supersymmetric scenarios

CERN Document Server

Romanino, Andrea; Romanino, Andrea; Strumia, Alessandro

2002-01-01

We study if a sizeable muon electric dipole can arise in supersymmetric frameworks able to account for the tight experimental bounds on sfermion masses, like an appropriate flavor symmetry, or like a flavor-blind mechanism of SUSY breaking (in presence of radiative corrections charchteristic of GUT models, or due to Yukawa couplings of neutrinos in see-saw models). In some cases it is possible to evade the naive scaling d_mu/d_e = m_mu/m_e and obtain a d_mu as large as 10^{-22--23} e cm. In most cases d_mu is around 10^{-24--25} e cm and (d_mu/d_e)/(m_mu/m_e) is only slightly different from one: this ratio contains interesting informations on the source of the dipoles and on the texture of the lepton Yukawa matrix. We also update GUT predictions for mu --> e gamma and related processes.

The neutrino masses in SO(10) grand unified theory

International Nuclear Information System (INIS)

Leontaris, G.K.; Vergados, J.D.; Ioannina Univ.

1987-01-01

The neutrino masses and mixing are investigated in an SO(10) model in which the ten-dimensional and 126-dimensional representations are allowed to obtain vacuum expectation values. The parameters specifying the heavy Majorana neutrino mass matrix are constrained from the cosmological bound of light neutrino masses and the limits from ν μ ↔ ν τ oscillations. The implications of our model on 0ν-ββ decay and muon-number violating processes are explored. (orig.)

Calculation of the single lepton SUSY analysis limits in the cMSSM m0-m1/2 plane

CERN Document Server

Megas, Efstathios

2014-01-01

The goal of the summer student project was the calculation of the single lepton SUSY analysis limits in the cMSSM $m_0$-$m_{1/2}$ plane. To this end, the analysis code, the production of the ntuples and a familarization with the higgs combination tool was needed.

Human gut microbiota plays a role in the metabolism of drugs.

Science.gov (United States)

Jourova, Lenka; Anzenbacher, Pavel; Anzenbacherova, Eva

2016-09-01

The gut microbiome, an aggregate genome of trillions of microorganisms residing in the human gastrointestinal tract, is now known to play a critical role in human health and predisposition to disease. It is also involved in the biotransformation of xenobiotics and several recent studies have shown that the gut microbiota can affect the pharmacokinetics of orally taken drugs with implications for their oral bioavailability. Review of Pubmed, Web of Science and Science Direct databases for the years 1957-2016. Recent studies make it clear that the human gut microbiota can play a major role in the metabolism of xenobiotics and, the stability and oral bioavailability of drugs. Over the past 50 years, more than 30 drugs have been identified as a substrate for intestinal bacteria. Questions concerning the impact of the gut microbiota on drug metabolism, remain unanswered or only partially answered, namely (i) what are the molecular mechanisms and which bacterial species are involved? (ii) What is the impact of host genotype and environmental factors on the composition and function of the gut microbiota, (iii) To what extent is the composition of the intestinal microbiome stable, transmissible, and resilient to perturbation? (iv) Has past exposure to a given drug any impact on future microbial response, and, if so, for how long? Answering such questions should be an integral part of pharmaceutical research and personalised health care.

Operator analysis for quark and lepton masses in SO(10)

International Nuclear Information System (INIS)

Hall, L.J.

1993-01-01

A sequence of simple assumptions leads to a supersymmetric SO(10) theory with 8 predictions in addition to sin 2 θ: tanβ,M t ,kV cb ,M s M s /M d ,M d ,V ub and the amount of CP violation J. These predictions are presented, together with experiments which will test them

Non-universal gaugino masses and fine tuning implications for SUSY searches in the MSSM and the GNMSSM

CERN Document Server

Kaminska, Anna; Schmidt-Hoberg, Kai

2013-01-01

For the case of the MSSM and the most general form of the NMSSM (GNMSSM) we determine the reduction in the fine tuning that follows from allowing gaugino masses to be non-degenerate at the unification scale, taking account of the LHC8 bounds on SUSY masses, the Higgs mass bound, gauge coupling unification and the requirement of an acceptable dark matter density. We show that low-fine tuned points fall in the region of gaugino mass ratios predicted by specific unified and string models. For the case of the MSSM the minimum fine tuning is still large, approximately 1:60 allowing for a 3 GeV uncertainty in the Higgs mass (1:500 for the central value), but for the GNMSSM it is below 1:20. We find that the spectrum of SUSY states corresponding to the low-fine tuned points in the GNMSSM is often compressed, weakening the LHC bounds on coloured states. The prospect for testing the remaining low-fine-tuned regions at LHC14 is discussed.

Non-universal gaugino masses and fine tuning implications for SUSY searches in the MSSM and the GNMSSM

Energy Technology Data Exchange (ETDEWEB)

Kaminska, Anna [Oxford Univ. (United Kingdom). Centre for Theoretical Physics; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Ross, Graham G. [Oxford Univ. (United Kingdom). Centre for Theoretical Physics; Schmidt-Hoberg, Kai [European Lab. for Particle Physics (CERN), Geneva (Switzerland)

2013-08-15

For the case of the MSSM and the most general form of the NMSSM (GNMSSM) we determine the reduction in the fine tuning that follows from allowing gaugino masses to be non-degenerate at the unification scale, taking account of the LHC8 bounds on SUSY masses, the Higgs mass bound, gauge coupling unification and the requirement of an acceptable dark matter density. We show that low-fine tuned points fall in the region of gaugino mass ratios predicted by specific unified and string models. For the case of the MSSM the minimum fine tuning is still large, approximately 1:60 allowing for a 3 GeV uncertainty in the Higgs mass (1:500 for the central value), but for the GNMSSM it is below 1:20. We find that the spectrum of SUSY states corresponding to the low-fine tuned points in the GNMSSM is often compressed, weakening the LHC bounds on coloured states. The prospect for testing the remaining low-fine-tuned regions at LHC14 is discussed.

[Gut microbiome and psyche: paradigm shift in the concept of brain-gut axis].

Science.gov (United States)

Konturek, Peter C; Zopf, Yurdagül

2016-05-25

The concept of the brain-gut axis describes the communication between the central and enteric nervous system. The exchange of information takes place in both directions. The great advances in molecular medicine in recent years led to the discovery of an enormous number of microorganisms in the intestine (gut microbiome), which greatly affect the function of the brain-gut axis. Overview Numerous studies indicate that the dysfunction of the brain-gut axis could lead to both inflammatory and functional diseases of the gastrointestinal tract. Moreover, it was shown that a faulty composition of the gut microbiota in childhood influences the maturation of the central nervous system and thus may favor the development of mental disorders such as autism, depression, or other. An exact causal relationship between psyche and microbiome must be clarified by further studies in order to find new therapeutic options.

Complex coevolutionary history of symbiotic Bacteroidales bacteria of various protists in the gut of termites

Science.gov (United States)

Noda, Satoko; Hongoh, Yuichi; Sato, Tomoyuki; Ohkuma, Moriya

2009-01-01

Background The microbial community in the gut of termites is responsible for the efficient decomposition of recalcitrant lignocellulose. Prominent features of this community are its complexity and the associations of prokaryotes with the cells of cellulolytic flagellated protists. Bacteria in the order Bacteroidales are involved in associations with a wide variety of gut protist species as either intracellular endosymbionts or surface-attached ectosymbionts. In particular, ectosymbionts exhibit distinct morphological patterns of the associations. Therefore, these Bacteroidales symbionts provide an opportunity to investigate not only the coevolutionary relationships with the host protists and their morphological evolution but also how symbiotic associations between prokaryotes and eukaryotes occur and evolve within a complex symbiotic community. Results Molecular phylogeny of 31 taxa of Bacteroidales symbionts from 17 protist genera in 10 families was examined based on 16S rRNA gene sequences. Their localization, morphology, and specificity were also examined by fluorescent in situ hybridizations. Although a monophyletic grouping of the ectosymbionts occurred in three related protist families, the symbionts of different protist genera were usually dispersed among several phylogenetic clusters unique to termite-gut bacteria. Similar morphologies of the associations occurred in multiple lineages of the symbionts. Nevertheless, the symbionts of congeneric protist species were closely related to one another, and in most cases, each host species harbored a unique Bacteroidales species. The endosymbionts were distantly related to the ectosymbionts examined so far. Conclusion The coevolutionary history of gut protists and their associated Bacteroidales symbionts is complex. We suggest multiple independent acquisitions of the Bacteroidales symbionts by different protist genera from a pool of diverse bacteria in the gut community. In this sense, the gut could serve as a

Phenomenology of GUT-less Supersymmetry Breaking

CERN Document Server

Ellis, Jonathan Richard; Sandick, Pearl

2007-01-01

We study models in which supersymmetry breaking appears at an intermediate scale, M_{in}, below the GUT scale. We assume that the soft supersymmetry-breaking parameters of the MSSM are universal at M_{in}, and analyze the morphology of the constraints from cosmology and collider experiments on the allowed regions of parameter space as M_{in} is reduced from the GUT scale. We present separate analyses of the (m_{1/2},m_0) planes for tan(beta)=10 and tan(beta)=50, as well as a discussion of non-zero trilinear couplings, A_0. Specific scenarios where the gaugino and scalar masses appear to be universal below the GUT scale have been found in mirage-mediation models, which we also address here. We demand that the lightest neutralino be the LSP, and that the relic neutralino density not conflict with measurements by WMAP and other observations. At moderate values of M_{in}, we find that the allowed regions of the (m_{1/2},m_0) plane are squeezed by the requirements of electroweak symmetry breaking and that the ligh...

Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

DEFF Research Database (Denmark)

Mikkelsen, Kristian H; Frost, Morten; Bahl, Martin Iain

2015-01-01

The gut microbiota has been designated as an active regulator of glucose metabolism and metabolic phenotype in a number of animal and human observational studies. We evaluated the effect of removing as many bacteria as possible by antibiotics on postprandial physiology in healthy humans. Meal tests...... with measurements of postprandial glucose tolerance and postprandial release of insulin and gut hormones were performed before, immediately after and 6 weeks after a 4-day, broad-spectrum, per oral antibiotic cocktail (vancomycin 500 mg, gentamycin 40 mg and meropenem 500 mg once-daily) in a group of 12 lean...... and glucose tolerant males. Faecal samples were collected for culture-based assessment of changes in gut microbiota composition. Acute and dramatic reductions in the abundance of a representative set of gut bacteria was seen immediately following the antibiotic course, but no changes in postprandial glucose...

Gut-Brain Axis and Behavior.

Science.gov (United States)

Martin, Clair R; Mayer, Emeran A

2017-01-01

In the last 5 years, interest in the interactions among the gut microbiome, brain, and behavior has exploded. Preclinical evidence supports a role of the gut microbiome in behavioral responses associated with pain, emotion, social interactions, and food intake. Limited, but growing, clinical evidence comes primarily from associations of gut microbial composition and function to behavioral and clinical features and brain structure and function. Converging evidence suggests that the brain and the gut microbiota are in bidirectional communication. Observed dysbiotic states in depression, chronic stress, and autism may reflect altered brain signaling to the gut, while altered gut microbial signaling to the brain may play a role in reinforcing brain alterations. On the other hand, primary dysbiotic states due to Western diets may signal to the brain, altering ingestive behavior. While studies performed in patients with depression and rodent models generated by fecal microbial transfer from such patients suggest causation, evidence for an influence of acute gut microbial alterations on human behavioral and clinical parameters is lacking. Only recently has an open-label microbial transfer therapy in children with autism tentatively validated the gut microbiota as a therapeutic target. The translational potential of preclinical findings remains unclear without further clinical investigation. © 2017 Nestec Ltd., Vevey/S. Karger AG, Basel.

Metagenomic Surveys of Gut Microbiota

Directory of Open Access Journals (Sweden)

Rahul Shubhra Mandal

2015-06-01

Full Text Available Gut microbiota of higher vertebrates is host-specific. The number and diversity of the organisms residing within the gut ecosystem are defined by physiological and environmental factors, such as host genotype, habitat, and diet. Recently, culture-independent sequencing techniques have added a new dimension to the study of gut microbiota and the challenge to analyze the large volume of sequencing data is increasingly addressed by the development of novel computational tools and methods. Interestingly, gut microbiota maintains a constant relative abundance at operational taxonomic unit (OTU levels and altered bacterial abundance has been associated with complex diseases such as symptomatic atherosclerosis, type 2 diabetes, obesity, and colorectal cancer. Therefore, the study of gut microbial population has emerged as an important field of research in order to ultimately achieve better health. In addition, there is a spontaneous, non-linear, and dynamic interaction among different bacterial species residing in the gut. Thus, predicting the influence of perturbed microbe–microbe interaction network on health can aid in developing novel therapeutics. Here, we summarize the population abundance of gut microbiota and its variation in different clinical states, computational tools available to analyze the pyrosequencing data, and gut microbe–microbe interaction networks.

SUSY non-Abelian gauge models: exact beta function from one loop of perturbation theory

International Nuclear Information System (INIS)

Shifman, M.A.; Vajnshtejn, A.I.; Zakharov, V.I.

1985-01-01

The method for calculating the exact β function (to all orders in the coupling constant) proposed earlier in supersymmetric electrodynamics is extended. The starting point is the observation that the low-energy effective action is exhausted by one loop provided that the theory is regularized supersymmetrically both in the ultraviolet and infrared domains in four dimensions. The Pouli-Villars method of the ultraviolet regularization is used. Two methods for the infrared regularization are considered. The first one - quantization in a box with a finite volume L 3 - is universally applicable to anygauge theory. The second method is based on the effective Higgs mechanism for mass generation and requires the presence of certain matter superfields in the lagrangian. Within this method the necessary condition is the existence of flat directions, so called valeys, along which the vacuum energy vanishes. The theory is quantized near epsilon non-vanishing value of the scalar field from the bottom of the valley. After calculating the one-loop effective action one and the same exact expression is obtained for the β function within the both approaches, and it also coincides with our earlier result extracted from instanton calculus. A few remarks on the problem of anomalies in SUSY gauge theories are presented

Neutrino masses in the flipped SU(5) x U(1) and the SU(4) x O(4) GUT models

Energy Technology Data Exchange (ETDEWEB)

Ranfone, S.; Papageorgiu, E.

1992-03-01

We classify the different neutrino-mass pattern arising in string-inspired Grand Universal Theory (GUT) and supersymmetric GUT models based on the flipped SU(5)xU(1) and the SU(4)xO(4) gauge groups. Phenomenologically interesting spectra are obtained through the interplay of the two seesaw mechanisms present, with typical neutrino masses {approx}10{sup -3} eV in the supersymmetric GUT models and of order 0.1 - 10 KeV in the ordinary GUTs. (author).

Neutrino masses in the flipped SU(5)xU(1) and the SU(4)xO(4) GUT models

Energy Technology Data Exchange (ETDEWEB)

Papageorgiu, E.; Ranfone, S. (Rutherford Appleton Lab., Chilton (United Kingdom))

1992-05-21

We classify the different neutrino-mass patterns arising in string-inspired GUT and supersymmetric GUT models based on the flipped SU(5)xU(1) and the SU(4)xO(4) gauge groups. Phenomenologically interesting spectra are obtained through the interplay of the two seesaw mechanisms present, with typical neutrino masses {proportional to}10{sup -3} eV in the supersymmetric GUT models and of order 0.1-10 keV in the ordinary GUTs. (orig.).

Carbohydrates and the human gut microbiota.

Science.gov (United States)

Chassard, Christophe; Lacroix, Christophe

2013-07-01

Due to its scale and its important role in maintaining health, the gut microbiota can be considered as a 'new organ' inside the human body. Many complex carbohydrates are degraded and fermented by the human gut microbiota in the large intestine to both yield basic energy salvage and impact gut health through produced metabolites. This review will focus on the gut microbes and microbial mechanisms responsible for polysaccharides degradation and fermentation in the large intestine. Gut microbes and bacterial metabolites impact the host at many levels, including modulation of inflammation, and glucose and lipid metabolisms. A complex relationship occurs in the intestine between the human gut microbiota, diet and the host. Research on carbohydrates and gut microbiota composition and functionality is fast developing and will open opportunities for prevention and treatment of obesity, diabetes and other related metabolic disorders through manipulation of the gut ecosystem.

The human gut microbiome and its dysfunctions through the meta-omics prism.

Science.gov (United States)

Mondot, Stanislas; Lepage, Patricia

2016-05-01

The microorganisms inhabiting the human gut are abundant (10(14) cells) and diverse (approximately 500 species per individual). It is now acknowledged that the microbiota has coevolved with its host to achieve a symbiotic relationship, leading to physiological homeostasis. The gut microbiota ensures vital functions, such as food digestibility, maturation of the host immune system, and protection against pathogens. Over the last few decades, the gut microbiota has also been associated with numerous diseases, such as inflammatory bowel disease, irritable bowel syndrome, obesity, and metabolic diseases. In most of these pathologies, a microbial dysbiosis has been found, indicating shifts in the taxonomic composition of the gut microbiota and changes in its functionality. Our understanding of the influence of the gut microbiota on human health is still growing. Working with microorganisms residing in the gut is challenging since most of them are anaerobic and a vast majority (approximately 75%) are uncultivable to date. Recently, a wide range of new approaches (meta-omics) has been developed to bypass the uncultivability and reveal the intricate mechanisms that sustain gut microbial homeostasis. After a brief description of these approaches (metagenomics, metatranscriptomics, metaproteomics, and metabolomics), this review will discuss the importance of considering the gut microbiome as a structured ecosystem and the use of meta-omics to decipher dysfunctions of the gut microbiome in diseases. © 2016 New York Academy of Sciences.

Influence of feeding thermally peroxidized soybean oil on growth performance, digestibility, and gut integrity in finishing pigs.

Science.gov (United States)

Overholt, Martin F; Dilger, Anna C; Boler, Dustin D; Kerr, Brian J

2018-05-26

Consumption of peroxidized lipids has been shown to reduce pig performance and energy and lipid digestibility. Objectives of the current study were to evaluate the effect of feeding soybean oil (SO) with different levels of peroxidation on growth performance, lipid, N, and GE digestibility, plasma Trp, and gut integrity in finishing pigs. Fifty-six barrows (46.7 ± 5.1 kg initial BW) were randomly assigned to one of four diets in each of two dietary phases, containing either 10% fresh SO (22.5 °C) or thermally processed SO (45 °C for 288 h, 90 °C for 72 h, or 180 °C for 6 h), each infused with of 15 L/min of air. Peroxide values were 2.0, 17.4, 123.6, and 19.4 mEq/kg; 2,4-decadienal values were 2.07, 1.90, 912.15, and 915.49 mg/kg; and 4-hydroxynonenal concentrations were 0.66, 1.49, 170.48, and 82.80 mg/kg, for the 22.5, 45, 90, and 180 °C processed SO, respectively. Pigs were individually housed and fed ad libitum for 81 d to measure growth performance, including a metabolism period to collect urine and feces for determination of GE, lipid, N digestibility, and N retention. Following the last day of fecal and urine collection when pigs were in the metabolism crates, lactulose and mannitol were fed and subsequently measured in the urine to evaluate gut permeability, while markers of oxidative stress were evaluated in plasma, urine, and liver. There were no differences observed in ADFI (P = 0.91), but average daily gain (ADG) and gain:feed G:F were decreased in pigs fed 90 °C SO diet (P ≤ 0.07) compared to pigs fed the other SO diets. Pigs fed the 90 and 180 °C SO had the lowest (P = 0.05) DE as a % of GE compared to pigs fed the 22.5 °C SO, with pigs fed the 45 °C SO being intermediate. Lipid digestibility was similarly affected (P = 0.01) as energy digestibility, but ME as a % of DE was not affected by dietary treatment (P = 0.16). There were no effects of lipid peroxidation on N digested, N retained, or the urinary lactulose:mannitol ratio (P ≥ 0

Polystyrene microplastics induce microbiota dysbiosis and inflammation in the gut of adult zebrafish.

Science.gov (United States)

Jin, Yuanxiang; Xia, Jizhou; Pan, Zihong; Yang, Jiajing; Wang, Wenchao; Fu, Zhengwei

2018-04-01

Microplastic (MP) are environmental pollutants and have the potential to cause varying degrees of aquatic toxicity. In this study, the effects on gut microbiota of adult male zebrafish exposed for 14 days to 100 and 1000 μg/L of two sizes of polystyrene MP were evaluated. Both 0.5 and 50 μm-diameter spherical polystyrene MP increased the volume of mucus in the gut at a concentration of 1000 μg/L (about 1.456 × 10 10 particles/L for 0.5 μm and 1.456 × 10 4 particles/L for 50 μm). At the phylum level, the abundance of Bacteroidetes and Proteobacteria decreased significantly and the abundance of Firmicutes increased significantly in the gut after 14-day exposure to 1000 μg/L of both sizes of polystyrene MP. In addition, high throughput sequencing of the 16S rRNA gene V3-V4 region revealed a significant change in the richness and diversity of microbiota in the gut of polystyrene MP-exposed zebrafish. A more in depth analysis, at the genus level, revealed that a total of 29 gut microbes identified by operational taxonomic unit (OTU) analysis were significantly changed in both 0.5 and 50 μm-diameter polystyrene MP-treated groups. Moreover, it was observed that 0.5 μm polystyrene MP not only increased mRNA levels of IL1α, IL1β and IFN but also their protein levels in the gut, indicating that inflammation occurred after polystyrene MP exposure. Our findings suggest that polystyrene MP could induce microbiota dysbiosis and inflammation in the gut of adult zebrafish. Copyright © 2017 Elsevier Ltd. All rights reserved.

Dark Matter in the MSSM

Energy Technology Data Exchange (ETDEWEB)

Cotta, R.C.; Gainer, J.S.; Hewett, J.L.; Rizzo, T.G.; /SLAC

2009-04-07

We have recently examined a large number of points in the parameter space of the phenomenological MSSM, the 19-dimensional parameter space of the CP-conserving MSSM with Minimal Flavor Violation. We determined whether each of these points satisfied existing experimental and theoretical constraints. This analysis provides insight into general features of the MSSM without reference to a particular SUSY breaking scenario or any other assumptions at the GUT scale. This study opens up new possibilities for SUSY phenomenology both in colliders and in astrophysical experiments. Here we shall discuss the implications of this analysis relevant to the study of dark matter.

The Challenge of Determining SUSY Parameters in Focus-Point-Inspired Cases

CERN Document Server

Rolbiecki, K.; Kalinowski, J.; Moortgat-Pick, G.

2006-01-01

We discuss the potential of combined LHC and ILC experiments for SUSY searches in a difficult region of the parameter space, in which all sfermion masses are above the TeV scale. Precision analyses of cross sections of light chargino production and forward--backward asymmetries of decay leptons and hadrons at the ILC, together with mass information on \\tilde{\\chi}^0_2 and squarks from the LHC, allow us to fit rather precisely the underlying fundamental gaugino/higgsino MSSM parameters and to constrain the masses of the heavy virtual sparticles. For such analyses the complete spin correlations between the production and decay processes have to be taken into account. We also took into account expected experimental uncertainties.

PySLHA: a Pythonic interface to SUSY Les Houches accord data

International Nuclear Information System (INIS)

Buckley, Andy

2015-01-01

This paper describes the PySLHA package, a Python language module and program collection for reading, writing and visualising SUSY model data in the SLHA format. PySLHA can read and write SLHA data in a very general way, including the official SLHA2 extension and user customisations, and with arbitrarily deep indexing of data block entries and a dedicated, intuitive interface for particle data and decay information. The draft SLHA3 XSECTION feature is also fully supported. PySLHA can additionally read and write the legacy ISAWIG model format, and provides format conversion scripts. A publication-quality mass spectrum and decay chain plotting tool, slhaplot, is included in the package. (orig.)

On the vacuum of the minimal nonsupersymmetric SO(10) unification

CERN Document Server

Bertolini, Stefano; Malinsky, Michal

2010-01-01

We study a class of nonsupersymmetric SO(10) grand unified scenarios where the first stage of the symmetry breaking is driven by the vacuum expectation values of the 45-dimensional adjoint representation. Three decade old results claim that such a Higgs setting may lead exclusively to the flipped SU(5) x U(1) intermediate stage. We show that this conclusion is actually an artifact of the tree level potential. The study of the accidental global symmetries emerging in various limits of the scalar potential offers a simple understanding of the tree level result and a rationale for the drastic impact of quantum corrections. We scrutinize in detail the simplest and paradigmatic case of the 45_{H} + 16_{H} Higgs sector triggering the breaking of SO(10) to the standard electroweak model. We show that the minimization of the one-loop effective potential allows for intermediate SU(4)_C x SU(2)_L x U(1)_R and SU(3)_c x SU(2)_L x SU(2)_R x U(1)_{B-L} symmetric stages as well. These are the options favoured by gauge unif...

The gut microbiota and host health

NARCIS (Netherlands)

Marchesi, Julian R.; Adams, David H.; Fava, Francesca; Hermes, Gerben D.A.; Hirschfield, Gideon M.; Hold, Georgina; Quraishi, Mohammed N.; Kinross, James; Smidt, Hauke; Tuohy, Kieran M.; Thomas, Linda V.; Zoetendal, Erwin G.; Hart, Ailsa

2016-01-01

Over the last 10-15 years, our understanding of the composition and functions of the human gut microbiota has increased exponentially. To a large extent, this has been due to new 'omic' technologies that have facilitated large-scale analysis of the genetic and metabolic profile of this microbial

Direct SUSY dark matter detection-theoretical rates due to the spin

International Nuclear Information System (INIS)

Vergados, J D

2004-01-01

The recent WMAP data have confirmed that exotic dark matter together with the vacuum energy (cosmological constant) dominate in the flat Universe. Thus direct dark matter detection, consisting of detecting the recoiling nucleus, is central to particle physics and cosmology. Supersymmetry provides a natural dark matter candidate, the lightest supersymmetric particle (LSP). The relevant cross sections arise out of two mechanisms: (i) the coherent mode, due to the scalar interaction and (ii) the spin contribution arising from the axial current. In this paper we will focus on the spin contribution, which is expected to dominate for light targets. For both modes it is possible to obtain detectable rates, but in most models the expected rates are much lower than the present experimental goals. So one should exploit two characteristic signatures of the reaction, namely the modulation effect and in directional experiments the correlation of the event rates with the sun's motion. In standard non-directional experiments the modulation is small, less than 2 per cent. In the case of the directional event rates we would like to suggest that the experiments exploit two features of the process, which are essentially independent of the SUSY model employed, namely: (1) the forward-backward asymmetry, with respect to the sun's direction of motion, is very large and (2) the modulation is much larger, especially if the observation is made in a plane perpendicular to the sun's velocity. In this case the difference between maximum and minimum can be larger than 40 per cent and the phase of the earth at the maximum is direction dependent

Gut Microbiome and Infant Health: Brain-Gut-Microbiota Axis and Host Genetic Factors.

Science.gov (United States)

Cong, Xiaomei; Xu, Wanli; Romisher, Rachael; Poveda, Samantha; Forte, Shaina; Starkweather, Angela; Henderson, Wendy A

2016-09-01

The development of the neonatal gut microbiome is influenced by multiple factors, such as delivery mode, feeding, medication use, hospital environment, early life stress, and genetics. The dysbiosis of gut microbiota persists during infancy, especially in high-risk preterm infants who experience lengthy stays in the Neonatal intensive care unit (NICU). Infant microbiome evolutionary trajectory is essentially parallel with the host (infant) neurodevelopmental process and growth. The role of the gut microbiome, the brain-gut signaling system, and its interaction with the host genetics have been shown to be related to both short and long term infant health and bio-behavioral development. The investigation of potential dysbiosis patterns in early childhood is still lacking and few studies have addressed this host-microbiome co-developmental process. Further research spanning a variety of fields of study is needed to focus on the mechanisms of brain-gut-microbiota signaling system and the dynamic host-microbial interaction in the regulation of health, stress and development in human newborns.

Exploring flavor structure of supersymmetry breaking at B factories

International Nuclear Information System (INIS)

Goto, Toru; Shindou, Tetsuo; Tanaka, Minoru; Okada, Yasuhiro; Shimizu, Yasuhiro

2003-01-01

We investigate flavor physics at present and future B factories in order to distinguish supersymmetric models. We evaluate CP asymmetries in various B decay modes, Δm Bd , Δm Bs , and ε K in three supersymmetric models, i.e. the minimal supergravity, the SU(5) SUSY GUT with right handed neutrinos, and a supersymmetric model with U(2) flavor symmetry. The allowed regions of Δm Bs /Δm Bd and CP asymmetries in B → J/ψK S and b → sγ are different for the three models so that it is possible to distinguish the three models by precise determinations of these observables in near future experiments. (author)

Grand Unification as a Bridge Between String Theory and Phenomenology

Energy Technology Data Exchange (ETDEWEB)

Pati, Jogesh C.

2006-06-09

In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2){sub L} x SU(2){sub R} x SU(4){sup c} or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in {mu} {yields} e{gamma}, {tau} {yields} {mu}{gamma}, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

Grand Unification as a Bridge Between String Theory and Phenomenology

Science.gov (United States)

Pati, Jogesh C.

In the first part of this paper, we explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity — be it string/M-theory or a reincarnation — this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2)L × SU(2)R × SU(4)c or SO(10) symmetry in 4D in explaining (i) observed neutrino oscillations, (ii) baryogenesis via leptogenesis, and (iii) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in μ → eγ, τ → μγ, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M-theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

Grand Unification as a Bridge Between String Theory and Phenomenology

International Nuclear Information System (INIS)

Pati, J

2006-01-01

In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2) L x SU(2) R x SU(4) c or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in μ → eγ, τ → μγ, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88.

Science.gov (United States)

Larsson, Erik; Tremaroli, Valentina; Lee, Ying Shiuan; Koren, Omry; Nookaew, Intawat; Fricker, Ashwana; Nielsen, Jens; Ley, Ruth E; Bäckhed, Fredrik

2012-08-01

The gut microbiota has profound effects on host physiology but local host-microbial interactions in the gut are only poorly characterised and are likely to vary from the sparsely colonised duodenum to the densely colonised colon. Microorganisms are recognised by pattern recognition receptors such as Toll-like receptors, which signal through the adaptor molecule MyD88. To identify host responses induced by gut microbiota along the length of the gut and whether these required MyD88, transcriptional profiles of duodenum, jejunum, ileum and colon were compared from germ-free and conventionally raised wild-type and Myd88-/- mice. The gut microbial ecology was assessed by 454-based pyrosequencing and viruses were analysed by PCR. The gut microbiota modulated the expression of a large set of genes in the small intestine and fewer genes in the colon but surprisingly few microbiota-regulated genes required MyD88 signalling. However, MyD88 was essential for microbiota-induced colonic expression of the antimicrobial genes Reg3β and Reg3γ in the epithelium, and Myd88 deficiency was associated with both a shift in bacterial diversity and a greater proportion of segmented filamentous bacteria in the small intestine. In addition, conventionally raised Myd88-/- mice had increased expression of antiviral genes in the colon, which correlated with norovirus infection in the colonic epithelium. This study provides a detailed description of tissue-specific host transcriptional responses to the normal gut microbiota along the length of the gut and demonstrates that the absence of MyD88 alters gut microbial ecology.

String flipped SO(10) model from Z4 orbifold

International Nuclear Information System (INIS)

Sato, H.; Shimojo, M.

1993-01-01

We search all possible string grand-unified-theory models obtained from heterotic superstrings compactified on a Z 4 orbifold with one Wilson line. It is shown that there is an essentially unique anomaly-free flipped SO(10) model with three generations plus one mirror conjugate generation of matter fields. We derive effective Yukawa interactions and examine the structure of mass matrices as well as a possible scenario of string coupling unification. The four-generation Z 4 orbifold model is a phenomenologically viable model beyond the minimal supersymmetric standard one

Some features of SUSY breaking in N=2 supergravity

International Nuclear Information System (INIS)

Cecotti, S.; Giradello, L.; Porrati, M.

1984-08-01

We discuss some features of SUSY breaking in N=2 Supergravity. Firstly, we show that in a general N=2 Sugra model (constructed according to the tensor calculus) all stationary points of the potential, at Λ=0, are fully supersymmetric if the compensating multiplet is not gauged. Thus a viable super-Higgs effect in N=2 supergravity can occur only in the presence of a Fayet-Iliopoulos term. Then we present an explicit model with two scales of breaking in anti-de Sitter space. Moreover, the ratio of the two gravitino masses is sliding i.e. not determined by the classical potential. In the extreme situation one of the gravitino mass equals √-Λ/3, and thus we have partial super-Higgs (in AdS space). The cosmological constant may be arranged to an arbitrary small value while keeping the mass of the heavy gravitino constant. (author)

Gut Homeostasis, Microbial Dysbiosis, and Opioids.

Science.gov (United States)

Wang, Fuyuan; Roy, Sabita

2017-01-01

Gut homeostasis plays an important role in maintaining animal and human health. The disruption of gut homeostasis has been shown to be associated with multiple diseases. The mutually beneficial relationship between the gut microbiota and the host has been demonstrated to maintain homeostasis of the mucosal immunity and preserve the integrity of the gut epithelial barrier. Currently, rapid progress in the understanding of the host-microbial interaction has redefined toxicological pathology of opioids and their pharmacokinetics. However, it is unclear how opioids modulate the gut microbiome and metabolome. Our study, showing opioid modulation of gut homeostasis in mice, suggests that medical interventions to ameliorate the consequences of drug use/abuse will provide potential therapeutic and diagnostic strategies for opioid-modulated intestinal infections. The study of morphine's modulation of the gut microbiome and metabolome will shed light on the toxicological pathology of opioids and its role in the susceptibility to infectious diseases.

Acromyrmex Leaf-Cutting Ants Have Simple Gut Microbiota with Nitrogen-Fixing Potential.

Science.gov (United States)

Sapountzis, Panagiotis; Zhukova, Mariya; Hansen, Lars H; Sørensen, Søren J; Schiøtt, Morten; Boomsma, Jacobus J

2015-08-15

Ants and termites have independently evolved obligate fungus-farming mutualisms, but their gardening procedures are fundamentally different, as the termites predigest their plant substrate whereas the ants deposit it directly on the fungus garden. Fungus-growing termites retained diverse gut microbiota, but bacterial gut communities in fungus-growing leaf-cutting ants have not been investigated, so it is unknown whether and how they are specialized on an exclusively fungal diet. Here we characterized the gut bacterial community of Panamanian Acromyrmex species, which are dominated by only four bacterial taxa: Wolbachia, Rhizobiales, and two Entomoplasmatales taxa. We show that the Entomoplasmatales can be both intracellular and extracellular across different gut tissues, Wolbachia is mainly but not exclusively intracellular, and the Rhizobiales species is strictly extracellular and confined to the gut lumen, where it forms biofilms along the hindgut cuticle supported by an adhesive matrix of polysaccharides. Tetracycline diets eliminated the Entomoplasmatales symbionts but hardly affected Wolbachia and only moderately reduced the Rhizobiales, suggesting that the latter are protected by the biofilm matrix. We show that the Rhizobiales symbiont produces bacterial NifH proteins that have been associated with the fixation of nitrogen, suggesting that these compartmentalized hindgut symbionts alleviate nutritional constraints emanating from an exclusive fungus garden diet reared on a substrate of leaves. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Multijet Background Estimation For SUSY Searches And Particle Flow Offline Reconstruction Using The ATLAS Detector At The LHC

CERN Document Server

AUTHOR|(SzGeCERN)731691

This thesis describes the jet smearing method, a data-driven technique for estimating the multijet background to Supersymmetry (SUSY) searches using the ATLAS detector at the Large Hadron Collider (LHC). The final 2011 and 2012 “ATLAS jets, missing transverse energy and zero leptons analysis” searches for SUSY are also documented. These analyses used the full ATLAS 2011 4.7 fb^{-1} $\\sqrt{s}$ = 7 TeV and 2012 20.3 fb$^{-1}$ $\\sqrt{s}$ = 8 TeV data sets. No statistically significant excess was found in either of these analyses; therefore, 95% C.L. mass exclusion limits were set on the mSUGRA/CMSSM m$_{0}$-m$_{1/2}$ and $m_{\\tilde{q}}$-$m_{\\tilde{g}}$ mass planes, and the simplified squark-gluino-neutralino pMSSM model. The jet smearing method was used in these analyses to estimate the multijet distributions of the Signal, Validation and Control Regions and also to calculate the multijet background Transfer Factors. This thesis also describes the missing transverse energy (E$_{miss}^{T}$ ) performance studi...

Susy-QCD corrections to neutrlino pair production in association with a jet

Energy Technology Data Exchange (ETDEWEB)

Cullen, Gavin [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Greiner, Nicolas; Heinrich, Gudrun [Max-Planck-Institut fuer Physik, Muenchen (Germany)

2012-12-15

We present the NLO Susy-QCD corrections to the production of a pair of the lightest neutralinos plus one jet at the LHC, appearing as a monojet signature in combination with missing energy. We fully include all non-resonant diagrams, i.e. we do not assume that production and decay factorise. We derive a parameter point based on the p19MSSM which is compatible with current experimental bounds and show distributions based on missing transverse energy and jet observables. Our results are produced with the program GoSam for automated one-loop calculations in combination with MadDipole/- MadGraph for the real radiation part.

Search for SUperSYmmetry (SUSY) in Opposite Sign (OS) di-lepton final states with Parked Data collected at $\\sqrt{s}$ = 8 TeV using the CMS detector

CERN Document Server

Bhattacharya, Saptaparna

2015-01-01

The Large Hadron Collider (LHC) has had a very successful data-taking phase with Run 1. After the discovery of the Higgs, confirming the predictions of the Standard Model (SM), the focus is on finding new physics, especially in the context of supersymmetry (SUSY). One of the potential hiding places of natural SUSY is in models with compressed spectra, that is, models where the mass difference between the parent SUSY particle and the Lightest Supersymmetric Particle (LSP) is small. Such signals are characterized by low transverse momentum (p${_T}$) objects, low hadronic activity and missing transverse energy (MET). In this analysis, we focus on di-lepton final states, specifically in the low p${_T}$ regime. We use 7.4 fb$^{-1}$ of parked data collected at $\\sqrt{s}$ = 8 TeV. The analysis is enabled by the use of triggers that place no restrictions on the di-lepton p${_T}$, instead relying on methods like Initial State Radiation (ISR) tagging by triggering on a high p${_T}$ photon, to reduce the trigger rate....

Interaction between gut immunity and polysaccharides.

Science.gov (United States)

Huang, Xiaojun; Nie, Shaoping; Xie, Mingyong

2017-09-22

The human gut is colonized with a vast and diverse microbial ecosystem, and these bacteria play fundamental roles in the well being of our bodies. Gut-associated lymphoid tissues, the largest mucosal immune system, should never be overlooked for their profound effect in maintaining the host immunity. Therefore, we discussed the relationship between gut immunity and host health, primarily from two aspects: the homeostasis of gut microbiota, and the function of gut-associated lymphoid tissues. Polysaccharides, widely concerned as bioactive macromolecules in recent centuries, have been proved to benefit the intestinal health. Dietary polysaccharides can improve the ratio of probiotics, regulate the intestinal microenvironment like decreasing the gut pH, and stimulate the macrophages or lymphocytes in gut tissues to fight against diseases like cancer. Based on various experimental and clinical evidence, the impacts of dietary polysaccharides on intestinal health are summarized, in order to reveal the possible immunomodulatory mechanisms of polysaccharides.

Supersymmetric seesaw inflection

International Nuclear Information System (INIS)

Aulakh, Charanjit S.; Garg, Ila

2013-01-01

We showed that Supersymmetric Unified theories which explain small neutrino masses via renormalizable Type-I-see-saw mechanism can also support slow roll inflection point inflation. In such a scenario inflation occurs along a MSSM D-flat direction associated with gauge invariant combination of Higgs, slepton and right handed sneutrino. The scale of inflation is set by right handed neutrino mass M υc ∼10 6 10 12 GeV and inflation parameters are determined in terms of Dirac and Majorana couplings responsible for neutrino masses. The fine tuning conditions to have effective slow roll inflation are determined in terms of superpotential parameters (Dirac and Majorana couplings). This is in contrast to MSSM or Dirac neutrino inflection scenarios where fine tuning conditions are on soft Susy breaking parameters. In our case M υc ≫ M Susy , so soft Susy breaking parameters have hardly any role to play in fine tuning. The fine tuning conditions are thus radiatively stable due to nonrenormalization theorems. Reheating occurs via instant preheating which dumps all the inflation energy into MSSM degrees of freedom giving a high reheat temperature T rh ≅ M υc 10 6 GeV ∼ 10 1l 10 15 GeV. We also examined how this scenario can be embedded in realistic New Minimal Supersymmetric SO(10) Grand Unified Theory. (author)

Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease.

Science.gov (United States)

Mangalam, Ashutosh; Shahi, Shailesh K; Luckey, David; Karau, Melissa; Marietta, Eric; Luo, Ningling; Choung, Rok Seon; Ju, Josephine; Sompallae, Ramakrishna; Gibson-Corley, Katherine; Patel, Robin; Rodriguez, Moses; David, Chella; Taneja, Veena; Murray, Joseph

2017-08-08

The human gut is colonized by a large number of microorganisms (∼10 13 bacteria) that support various physiologic functions. A perturbation in the healthy gut microbiome might lead to the development of inflammatory diseases, such as multiple sclerosis (MS). Therefore, gut commensals might provide promising therapeutic options for treating MS and other diseases. We report the identification of human gut-derived commensal bacteria, Prevotella histicola, which can suppress experimental autoimmune encephalomyelitis (EAE) in a human leukocyte antigen (HLA) class II transgenic mouse model. P. histicola suppresses disease through the modulation of systemic immune responses. P. histicola challenge led to a decrease in pro-inflammatory Th1 and Th17 cells and an increase in the frequencies of CD4 + FoxP3 + regulatory T cells, tolerogenic dendritic cells, and suppressive macrophages. Our study provides evidence that the administration of gut commensals may regulate a systemic immune response and may, therefore, have a possible role in treatment strategies for MS. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis.

Science.gov (United States)

Goto, Tsuyoshi; Kim, Young-Il; Furuzono, Tomoya; Takahashi, Nobuyuki; Yamakuni, Kanae; Yang, Ha-Eun; Li, Yongjia; Ohue, Ryuji; Nomura, Wataru; Sugawara, Tatsuya; Yu, Rina; Kitamura, Nahoko; Park, Si-Bum; Kishino, Shigenobu; Ogawa, Jun; Kawada, Teruo

2015-04-17

Our previous study has shown that gut lactic acid bacteria generate various kinds of fatty acids from polyunsaturated fatty acids such as linoleic acid (LA). In this study, we investigated the effects of LA and LA-derived fatty acids on the activation of peroxisome proliferator-activated receptors (PPARs) which regulate whole-body energy metabolism. None of the fatty acids activated PPARδ, whereas almost all activated PPARα in luciferase assays. Two fatty acids potently activated PPARγ, a master regulator of adipocyte differentiation, with 10-oxo-12(Z)-octadecenoic acid (KetoA) having the most potency. In 3T3-L1 cells, KetoA induced adipocyte differentiation via the activation of PPARγ, and increased adiponectin production and insulin-stimulated glucose uptake. These findings suggest that fatty acids, including KetoA, generated in gut by lactic acid bacteria may be involved in the regulation of host energy metabolism. Copyright © 2015 Elsevier Inc. All rights reserved.

Impact of human milk bacteria and oligosaccharides on neonatal gut microbiota establishment and gut health.

Science.gov (United States)

Jost, Ted; Lacroix, Christophe; Braegger, Christian; Chassard, Christophe

2015-07-01

Neonatal gut microbiota establishment represents a crucial stage for gut maturation, metabolic and immunologic programming, and consequently short- and long-term health status. Human milk beneficially influences this process due to its dynamic profile of age-adapted nutrients and bioactive components and by providing commensal maternal bacteria to the neonatal gut. These include Lactobacillus spp., as well as obligate anaerobes such as Bifidobacterium spp., which may originate from the maternal gut via an enteromammary pathway as a novel form of mother-neonate communication. Additionally, human milk harbors a broad range of oligosaccharides that promote the growth and activity of specific bacterial populations, in particular, Bifidobacterium and Bacteroides spp. This review focuses on the diversity and origin of human milk bacteria, as well as on milk oligosaccharides that influence neonatal gut microbiota establishment. This knowledge can be used to develop infant formulae that more closely mimic nature's model and sustain a healthy gut microbiota. © The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

First Foods and Gut Microbes

DEFF Research Database (Denmark)

Laursen, Martin Frederik; Bahl, Martin Iain; Michaelsen, Kim F.

2017-01-01

, are generally recognized to be of particular importance for the healthy development of children. While dietary changes are known to affect the adult gut microbiota, there is a gap in our knowledge on how the introduction of new dietary components into the diet of infants/young children affects the gut...... microbiota development. This perspective paper summarizes the currently very few studies addressing the effects of complementary diet on gut microbiota, and highlights the recent finding that transition to family foods greatly impacts the development of gut microbial diversity. Further, we discuss potential......(breast/formula). Consequently, the neonatal period and early infancy has attracted much attention. However, after this first period the gut microbial composition continues to develop until the age of 3 years, and these 1st years have been designated "a window of opportunity" for microbial modulation. The beginning and end...

Hh pathway expression in human gut tissues and in inflammatory gut diseases

NARCIS (Netherlands)

Nielsen, Corinne M.; Williams, Jerrell; van den Brink, Gijs R.; Lauwers, Gregory Y.; Roberts, Drucilla J.

2004-01-01

Sonic hedgehog (Shh) directs early gut patterning via epithelial-mesenchymal signaling and remains expressed in endoderm-derived tissues into the adult period. In human adult gut epithelium SHH/SHH expression is strongest in basal layers, which suggests that SHH may function in the maintenance of

Alternation of Gut Microbiota in Patients with Pulmonary Tuberculosis

Directory of Open Access Journals (Sweden)

Mei Luo

2017-11-01

Full Text Available One-third of the world's population has been infected with Mycobacterium tuberculosis (M. tuberculosis, a primary pathogen of the mammalian respiratory system, while about 10% of latent infections progress to active tuberculosis (TB, indicating that host and environmental factors may determine the outcomes such as infection clearance/persistence and treatment prognosis. The gut microbiota is essential for development of host immunity, defense, nutrition and metabolic homeostasis. Thus, the pattern of gut microbiota may contribute to M. tuberculosis infection and prognosis. In current study we characterized the differences in gut bacterial communities in new tuberculosis patients (NTB, recurrent tuberculosis patients (RTB, and healthy control. The abundance-based coverage estimator (ACE showed the diversity index of the gut microbiota in the patients with recurrent tuberculosis was increased significantly compared with healthy controls (p < 0.05. At the phyla level, Actinobacteria and Proteobacteria, which contain many pathogenic species, were significantly enriched in the feces RTB patients. Conversely, phylum Bacteroidetes, containing a variety of beneficial commensal organisms, was reduced in the patients with the recurrent tuberculosis compared to healthy controls. The Gram-negative genus Prevotella of oral origin from phylum of Bacteroidetes and genus Lachnospira from phylum of Firmicutes were significantly decreased in both the new and recurrent TB patient groups, compared with the healthy control group (p < 0.05. We also found that there was a positive correlation between the gut microbiota and peripheral CD4+ T cell counts in the patients. This study, for the first time, showed associations between gut microbiota with tuberculosis and its clinical outcomes. Maintaining eubiosis, namely homeostasis of gut microbiota, may be beneficial for host recovery and prevention of recurrence of M. tuberculosis infection.

Complete Cubic and Quartic Couplings of 16 and $\\bar{16}$ in SO(10) Unification

CERN Document Server

Syed, R M; Nath, Pran; Syed, Raza M.

2001-01-01

A recently derived basic theorem on the decomposition of SO(2N) vertices is used to obtain a complete analytic determination of all SO(10) invariant cubic superpotential couplings involving $16_{\\pm}$ semispinors of SO(10) chirality $\\pm$ and tensor representations. In addition to the superpotential couplings computed previously using the basic theorem involving the 10, 120 and $\\bar{126}$ tensor representations we compute here couplings involving the 1, 45 and 210 dimensional tensor representations, i.e., we compute the $\\bar{16}_{\\mp}16_{\\pm}1$,$\\bar{16}_{\\mp}16_{\\pm}45$ and $\\bar{16}_{\\mp}16_{\\pm}210$ Higgs couplings in the superpotential. A complete determination of dimension five operators in the superpotential arising from the mediation of the 1, 45 and 210 dimensional representations is also given. The vector couplings $\\bar{16}_{\\pm}16_{\\pm}1$, $\\bar{16}_{\\pm}16_{\\pm}45$ and $\\bar{16}_{\\pm}16_{\\pm}210$ are also analyzed. The role of large tensor representations and the possible application of results ...

Gut-associated lymphoid tissue, gut microbes and susceptibility to experimental autoimmune encephalomyelitis.

Science.gov (United States)

Stanisavljević, S; Lukić, J; Momčilović, M; Miljković, M; Jevtić, B; Kojić, M; Golić, N; Mostarica Stojković, M; Miljković, D

2016-06-01

Gut microbiota and gut-associated lymphoid tissue have been increasingly appreciated as important players in pathogenesis of various autoimmune diseases, including multiple sclerosis. Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis that can be induced with an injection of spinal cord homogenate emulsified in complete Freund's adjuvant in Dark Agouti (DA) rats, but not in Albino Oxford (AO) rats. In this study, mesenteric lymph nodes (MLN), Peyer's patches (PP) and gut microbiota were analysed in these two rat strains. There was higher proportion of CD4(+) T cells and regulatory T cells in non-immunised DA rats in comparison to AO rats. Also, DA rat MLN and PP cells were higher producers of pro-inflammatory cytokines interferon-γ and interleukin-17. Finally, microbial analyses showed that uncultivated species of Turicibacter and Atopostipes genus were exclusively present in AO rats, in faeces and intestinal tissue, respectively. Thus, it is clear that in comparison of an EAE-susceptible with an EAE-resistant strain of rats, various discrepancies at the level of gut associated lymphoid tissue, as well as at the level of gut microbiota can be observed. Future studies should determine if the differences have functional significance for EAE pathogenesis.

Diphoton resonance in F-theory inspired flipped SO(10)

Energy Technology Data Exchange (ETDEWEB)

Leontaris, George K. [Ioannina University, Physics Department, Theory Division, Ioannina (Greece); Shafi, Qaisar [University of Delaware, Department of Physics and Astronomy, Bartol Research Institute, Newark, DE (United States)

2016-10-15

Motivated by the di-photon excess at 750 GeV reported by the ATLAS and CMS experiments, we present an F-theory inspired flipped SO(10) model embedded in E{sub 6}. The low energy spectrum includes the three MSSM chiral families, vector-like colour triplets, several pairs of charged SU(2){sub L} singlet fields (E{sup c}, anti E{sup c}), as well as MSSM singlets, one or more of which could contribute to the di-photon resonance. A total decay width in the multi-GeV range can arise from couplings involving the singlet and MSSM fields. (orig.)

Microbial diversity and digestive enzyme activities in the gut of earthworms found in sawmill industries in Abeokuta, Nigeria

Directory of Open Access Journals (Sweden)

Bamidele Julius A.

2014-09-01

Full Text Available The growing demand for wood has resulted in large volumes of wood wastes that are daily released to the soil from the activities of sawmills in South-Western Nigeria. In an attempt to setup a bioremediation model for sawdust, this study therefore aimed at evaluating microbial diversity, and the level of digestive enzymes in the gut of earthworms (Eudrilus eugeniae, Libyodrilus violaceous and Hyperiodrilus africanus of sawmill origin. Four major sawmills located in Abeokuta (7o9’12” N - 3o19’35” E, namely Lafenwa, Sapon, Isale-Ake and Kotopo sawmills were used for this study. The arboretum of the Federal University of Agriculture, Abeokuta was used as control. Gut microbial analysis was carried out using the pour-plate method while digestive enzyme activities in the earthworm guts were done by the spectrophotometric method. Higher microbial counts (28.5±0.1x10³-97.0±0.1x10³cfu for bacteria and 7.0±0.1x10³-96.0±0.1x10³cfu for fungi and microbial diversity were recorded in the gut of earthworms of the sawmill locations than those of the control site (17.5±0.1x10³cfu for bacteria and 4.5±0.1x10³cfu for fungi. Streptococcus mutans and Proteus spp.were common in the gut of E. eugeniae, and L. violaceous from the study sawmills, while Streptococcus mutans were also identified in H. africanus, but absent in the gut of E. eugeniae from the control site. Cellulase (48.67±0.02mg/g and lipase (1.81±0.01mg/g activities were significantly higher (p<0.05 in the gut of earthworms from the control site than those of the study sawmills. Furthermore, amylase (α and β activity was highest in the gut of earthworms from the sawmills. Variations observed in the gut microbial and digestive enzyme activities of earthworms from the study sawmills as compared to the control site suggests that earthworms, especially E. eugeniae, could be a better organism for use as bioremediator of wood wastes. Rev. Biol. Trop. 62 (3: 1241-1249. Epub 2014 September

Role of the normal gut microbiota.

Science.gov (United States)

Jandhyala, Sai Manasa; Talukdar, Rupjyoti; Subramanyam, Chivkula; Vuyyuru, Harish; Sasikala, Mitnala; Nageshwar Reddy, D

2015-08-07

Relation between the gut microbiota and human health is being increasingly recognised. It is now well established that a healthy gut flora is largely responsible for overall health of the host. The normal human gut microbiota comprises of two major phyla, namely Bacteroidetes and Firmicutes. Though the gut microbiota in an infant appears haphazard, it starts resembling the adult flora by the age of 3 years. Nevertheless, there exist temporal and spatial variations in the microbial distribution from esophagus to the rectum all along the individual's life span. Developments in genome sequencing technologies and bioinformatics have now enabled scientists to study these microorganisms and their function and microbe-host interactions in an elaborate manner both in health and disease. The normal gut microbiota imparts specific function in host nutrient metabolism, xenobiotic and drug metabolism, maintenance of structural integrity of the gut mucosal barrier, immunomodulation, and protection against pathogens. Several factors play a role in shaping the normal gut microbiota. They include (1) the mode of delivery (vaginal or caesarean); (2) diet during infancy (breast milk or formula feeds) and adulthood (vegan based or meat based); and (3) use of antibiotics or antibiotic like molecules that are derived from the environment or the gut commensal community. A major concern of antibiotic use is the long-term alteration of the normal healthy gut microbiota and horizontal transfer of resistance genes that could result in reservoir of organisms with a multidrug resistant gene pool.

Supersymmetric GUTs and cosmology

International Nuclear Information System (INIS)

Lazarides, G.; Shafi, Q.

1982-06-01

By examining the behaviour of supersymmetric GUTs in the very early universe we find two classes of realistic models. In one of them supersymmetry is broken at or near the superheavy GUT scale. The cosmological implications of such models are expected to be similar to those of nonsupersymmetric GUTs. In the second class of models, the superheavy GUT scale is related to the supersymmetry breaking scale a la Witten. Two types of cosmological scenarios appear possible in this case, either with or without an intermediate (new) inflationary phase. They can be experimentally distinguished, since the former predicts an absence and the latter an observable number density of superheavy monopoles. A mechanism for generating baryon asymmetry in such models is pointed out. Further constraint on model building appears if global R invariance is employed to resolve the strong CP problem. (author)

The Gut Microbiota in Host Metabolism and Pathogen Challenges

DEFF Research Database (Denmark)

Holm, Jacob Bak

The human microbiota consists of a complex community of microbial cells that live on and inside each person in a close relationship with their host. The majority of the microbial cells are harboured by the gastro intestinal tract where 10-100 trillion bacteria reside. The microbiota is a dynamic...... community where both composition and function can be affected by changes in the local environment. With the microbiota containing ~150 times more genes than the human host, the microbiota provides a large modifiable “secondary genome” (metagenome). Within the last decade, changes in the gut microbiota...... composition has indeed been established as a factor contributing to the health of the host. Therefore, being able to understand, control and modify the gut microbiota is a promising way of improving health. The following thesis is based on four different projects investigating the murine gut microbiota...

Flavour and collider interplay for SUSY at LHC7

International Nuclear Information System (INIS)

Calibbi, L.; Hodgkinson, R.N.; Vives, O.; Jones Perez, J.; Masiero, A.

2012-01-01

The current 7 TeV run of the LHC experiment shall be able to probe gluino and squark masses up to values larger than 1 TeV. Assuming that hints for SUSY are found in the jets plus missing energy channel by the end of a 5 fb -1 run, we explore the flavour constraints on three models with a CMSSM-like spectrum: the CMSSM itself, a seesaw extension of the CMSSM, and Flavoured CMSSM. In particular, we focus on decays that might have been measured by the time the run is concluded, such as B s →μμ and μ→e γ. We also analyse constraints imposed by neutral meson bounds and electric dipole moments. The interplay between collider and flavour experiments is explored through the use of three benchmark scenarios, finding the flavour feedback useful in order to determine the model parameters and to test the consistency of the different models. (orig.)

N-anti N oscillation in SO(10) and SU(6) supersymmetric grand unified models

International Nuclear Information System (INIS)

Fujimoto, Y.; Zhiyong, Z.

1982-06-01

N-anti N oscillation in SO(10) and SU(6) S.G.U.M. is considered. We find a new type of diagram leading to a faster oscillation rate than in non-supersymmetric case. It is also noted that in SO(10) S.G.U.M. with intermediate SU(4)sub(C)xSU(2)sub(L)xSU(2)sub(R) symmetry N-anti N oscillation would be highly suppressed, which may not necessarily be the case for SU(6) S.G.U.M. (author)

Marked seasonal variation in the wild mouse gut microbiota.

Science.gov (United States)

Maurice, Corinne F; Knowles, Sarah C L; Ladau, Joshua; Pollard, Katherine S; Fenton, Andy; Pedersen, Amy B; Turnbaugh, Peter J

2015-11-01

Recent studies have provided an unprecedented view of the microbial communities colonizing captive mice; yet the host and environmental factors that shape the rodent gut microbiota in their natural habitat remain largely unexplored. Here, we present results from a 2-year 16 S ribosomal RNA gene sequencing-based survey of wild wood mice (Apodemus sylvaticus) in two nearby woodlands. Similar to other mammals, wild mice were colonized by 10 bacterial phyla and dominated by the Firmicutes, Bacteroidetes and Proteobacteria. Within the Firmicutes, the Lactobacillus genus was most abundant. Putative bacterial pathogens were widespread and often abundant members of the wild mouse gut microbiota. Among a suite of extrinsic (environmental) and intrinsic (host-related) factors examined, seasonal changes dominated in driving qualitative and quantitative differences in the gut microbiota. In both years examined, we observed a strong seasonal shift in gut microbial community structure, potentially due to the transition from an insect- to a seed-based diet. This involved decreased levels of Lactobacillus, and increased levels of Alistipes (Bacteroidetes phylum) and Helicobacter. We also detected more subtle but statistically significant associations between the gut microbiota and biogeography, sex, reproductive status and co-colonization with enteric nematodes. These results suggest that environmental factors have a major role in shaping temporal variations in microbial community structure within natural populations.

GUT Scale Fermion Mass Ratios

International Nuclear Information System (INIS)

Spinrath, Martin

2014-01-01

We present a series of recent works related to group theoretical factors from GUT symmetry breaking which lead to predictions for the ratios of quark and lepton Yukawa couplings at the unification scale. New predictions for the GUT scale ratios y μ /y s , y τ /y b and y t /y b in particular are shown and compared to experimental data. For this comparison it is important to include possibly large supersymmetric threshold corrections. Due to this reason the structure of the fermion masses at the GUT scale depends on TeV scale physics and makes GUT scale physics testable at the LHC. We also discuss how this new predictions might lead to predictions for mixing angles by discussing the example of the recently measured last missing leptonic mixing angle θ 13 making this new class of GUT models also testable in neutrino experiments

Gut Microbiota and Metabolic Disorders

Directory of Open Access Journals (Sweden)

Kyu Yeon Hur

2015-06-01

Full Text Available Gut microbiota plays critical physiological roles in the energy extraction and in the control of local or systemic immunity. Gut microbiota and its disturbance also appear to be involved in the pathogenesis of diverse diseases including metabolic disorders, gastrointestinal diseases, cancer, etc. In the metabolic point of view, gut microbiota can modulate lipid accumulation, lipopolysaccharide content and the production of short-chain fatty acids that affect food intake, inflammatory tone, or insulin signaling. Several strategies have been developed to change gut microbiota such as prebiotics, probiotics, certain antidiabetic drugs or fecal microbiota transplantation, which have diverse effects on body metabolism and on the development of metabolic disorders.

Finding viable models in SUSY parameter spaces with signal specific discovery potential

Science.gov (United States)

Burgess, Thomas; Lindroos, Jan Øye; Lipniacka, Anna; Sandaker, Heidi

2013-08-01

Recent results from ATLAS giving a Higgs mass of 125.5 GeV, further constrain already highly constrained supersymmetric models such as pMSSM or CMSSM/mSUGRA. As a consequence, finding potentially discoverable and non-excluded regions of model parameter space is becoming increasingly difficult. Several groups have invested large effort in studying the consequences of Higgs mass bounds, upper limits on rare B-meson decays, and limits on relic dark matter density on constrained models, aiming at predicting superpartner masses, and establishing likelihood of SUSY models compared to that of the Standard Model vis-á-vis experimental data. In this paper a framework for efficient search for discoverable, non-excluded regions of different SUSY spaces giving specific experimental signature of interest is presented. The method employs an improved Markov Chain Monte Carlo (MCMC) scheme exploiting an iteratively updated likelihood function to guide search for viable models. Existing experimental and theoretical bounds as well as the LHC discovery potential are taken into account. This includes recent bounds on relic dark matter density, the Higgs sector and rare B-mesons decays. A clustering algorithm is applied to classify selected models according to expected phenomenology enabling automated choice of experimental benchmarks and regions to be used for optimizing searches. The aim is to provide experimentalist with a viable tool helping to target experimental signatures to search for, once a class of models of interest is established. As an example a search for viable CMSSM models with τ-lepton signatures observable with the 2012 LHC data set is presented. In the search 105209 unique models were probed. From these, ten reference benchmark points covering different ranges of phenomenological observables at the LHC were selected.

SadA-Expressing Staphylococci in the Human Gut Show Increased Cell Adherence and Internalization

Directory of Open Access Journals (Sweden)

Arif Luqman

2018-01-01

Full Text Available Summary: A subgroup of biogenic amines, the so-called trace amines (TAs, are produced by mammals and bacteria and can act as neuromodulators. In the genus Staphylococcus, certain species are capable of producing TAs through the activity of staphylococcal aromatic amino acid decarboxylase (SadA. SadA decarboxylates aromatic amino acids to produce TAs, as well as dihydroxy phenylalanine and 5-hydroxytryptophan to thus produce the neurotransmitters dopamine and serotonin. SadA-expressing staphylococci were prevalent in the gut of most probands, where they are part of the human intestinal microflora. Furthermore, sadA-expressing staphylococci showed increased adherence to HT-29 cells and 2- to 3-fold increased internalization. Internalization and adherence was also increased in a sadA mutant in the presence of tryptamine. The α2-adrenergic receptor is required for enhanced adherence and internalization. Thus, staphylococci in the gut might contribute to gut activity and intestinal colonization. : Luqman et al. examine the sadA gene and argue that it contributes to TAs. They found that neuromodulator-producing staphylococci were present in the gut of most probands. The produced neuromodulators enhanced the adherence and internalization of staphylococci to cells in culture. Keywords: adherence, aromatic amino acid decarboxylase, gut microbiota, internalization, neuromodulator, neurotransmitter, staphylococcus

SU(7) GUT and evasion of the survival hypothesis

International Nuclear Information System (INIS)

Umemura, I.; Yamamoto, K.

1981-01-01

Characteristic features of an SU(7) GUT are discussed, in which the fundamental representation 7 consists of SU(5)'5 and its two singlets with charge q = +-1/2. The so-called survival hypothesis for fermions is naturally evaded by a kind of electric charge conservation due to q = +-1/2, and a brief comment on the suppression of the νsub(e) mass is given also. (orig.)

The gut microbiota in type 2 diabetes

DEFF Research Database (Denmark)

Nielsen, Trine; Allin, Kristine Højgaard; Pedersen, Oluf

2016-01-01

The exploration of the gut microbiota has intensified within the past decade with the introduction of cultivation-independent methods. By investigation of the gut bacterial genes, our understanding of the compositional and functional capability of the gut microbiome has increased. It is now widely...... recognized that the gut microbiota has profound effect on host metabolism and recently changes in the gut microbiota have been associated with type 2 diabetes. Animal models and human studies have linked changes in the gut microbiota to the induction of low-grade inflammation, altered immune response......, and changes in lipid and glucose metabolism. Several factors have been identified that might affect the healthy microbiota, potentially inducing a dysbiotic microbiota associated with a disease state. This increased understanding of the gut microbiota might potentially contribute to targeted intervention...

SU(2) symmetry and degeneracy from SUSY QM of a neutron in the magnetic field of a linear current

International Nuclear Information System (INIS)

Martinez, D.; Granados, V.D.; Mota, R.D.

2006-01-01

From SUSY ladder operators in momentum space of a neutron in the magnetic field of a linear current, we construct 2x2 matrix operators that together with the z-component of the total angular momentum satisfy the su(2) Lie algebra. We use this fact to explain the degeneracy of the energy spectrum

Testing SO(10)-inspired leptogenesis with low energy neutrino experiments

CERN Document Server

Di Bari, Pasquale

2011-01-01

We extend the results of a previous analysis of ours showing that, when both heavy and light flavour effects are taken into account, successful minimal (type I + thermal) leptogenesis with SO(10)-inspired relations is possible. Barring fine tuned choices of the parameters, these relations enforce a hierarchical RH neutrino mass spectrum that results into a final asymmetry dominantly produced by the next-to-lightest RH neutrino decays (N_2 dominated leptogenesis). We present the constraints on the whole set of low energy neutrino parameters. Allowing a small misalignment between the Dirac basis and the charged lepton basis as in the quark sector, the allowed regions enlarge and the lower bound on the reheating temperature gets relaxed to values as low as ~ 10^10 GeV. It is confirmed that for normal ordering (NO) there are two allowed ranges of values for the lightest neutrino mass: m_1 \\simeq (1-5)\\times 10^-3 eV and m_1\\simeq (0.03-0.1) eV. For m_1\\lesssim 0.01 eV the allowed region in the plane theta_13-thet...

Proton pump inhibitors affect the gut microbiome

NARCIS (Netherlands)

Imhann, Floris; Bonder, Marc Jan; Vich Vila, Arnau; Fu, Jingyuan; Mujagic, Zlatan; Vork, Lisa; Feenstra, Ettje T.; Jankipersadsing, Soesma A; Cenit, Maria Carmen; Harmsen, Hermie J M; Dijkstra, Gerard; Franke, Lude; Xavier, Ramnik J; Jonkers, Daisy; Wijmenga, Cisca; Weersma, Rinse K; Zhernakova, Alexandra

BACKGROUND AND AIMS: Proton pump inhibitors (PPIs) are among the top 10 most widely used drugs in the world. PPI use has been associated with an increased risk of enteric infections, most notably Clostridium difficile. The gut microbiome plays an important role in enteric infections, by resisting or

Early Life Experience and Gut Microbiome: The Brain-Gut-Microbiota Signaling System.

Science.gov (United States)

Cong, Xiaomei; Henderson, Wendy A; Graf, Joerg; McGrath, Jacqueline M

2015-10-01

Over the past decades, advances in neonatal care have led to substantial increases in survival among preterm infants. With these gains, recent concerns have focused on increases in neurodevelopment morbidity related to the interplay between stressful early life experiences and the immature neuroimmune systems. This interplay between these complex mechanisms is often described as the brain-gut signaling system. The role of the gut microbiome and the brain-gut signaling system have been found to be remarkably related to both short- and long-term stress and health. Recent evidence supports that microbial species, ligands, and/or products within the developing intestine play a key role in early programming of the central nervous system and regulation of the intestinal innate immunity. The purpose of this state-of-the-science review is to explore the supporting evidence demonstrating the importance of the brain-gut-microbiota axis in regulation of early life experience. We also discuss the role of gut microbiome in modulating stress and pain responses in high-risk infants. A conceptual framework has been developed to illustrate the regulation mechanisms involved in early life experience. The science in this area is just beginning to be uncovered; having a fundamental understanding of these relationships will be important as new discoveries continue to change our thinking, leading potentially to changes in practice and targeted interventions.

Antibiotics as deep modulators of gut microbiota: between good and evil.

Science.gov (United States)

Ianiro, Gianluca; Tilg, Herbert; Gasbarrini, Antonio

2016-11-01

The recent increase in our knowledge of human gut microbiota has changed our view on antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially harmful drugs, as their abuse appears to play a role in the pathogenesis of several disorders associated with microbiota impairment (eg, Clostridium difficile infection or metabolic disorders). Both drug-related factors (such as antibiotic class, timing of exposure or route of administration) and host-related factors appear to influence the alterations of human gut microbiota produced by antibiotics. Nevertheless, antibiotics are nowadays considered a reliable therapy for some non-communicable disorders, including IBS or hepatic encephalopathy. Moreover, some antibiotics can also act positively on gut microbiota, providing a so-called 'eubiotic' effect, by increasing abundance of beneficial bacteria. Therefore, antibiotics appear to change, for better or worse, the nature of several disorders, including IBS, IBD, metabolic disorders or liver disease. This reviews aims to address the potential of antibiotics in the development of major non-communicable disorders associated with the alteration of gut microbiota and on newly discovered therapeutic avenues of antibiotics beyond the cure of infectious diseases. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Complete cubic and quartic couplings of 16 and 16-bar in SO(10) unification

International Nuclear Information System (INIS)

Nath, Pran; Syed, Raza M.

2001-01-01

A recently derived basic theorem on the decomposition of SO(2N) vertices is used to obtain a complete analytic determination of all SO(10)-invariant cubic superpotential couplings involving 16 ± semispinors of SO(10) chirality ± and tensor representations. In addition to the superpotential couplings computed previously using the basic theorem involving the 10, 120 and 126-bar tensor representations we compute here couplings involving the 1-, 45- and 210-dimensional tensor representations, i.e., we compute the 16-bar -+ 16 ± 1, 16-bar -+ 16 ± 45 and 16-bar -+ 16 ± 210 Higgs couplings in the superpotential. A complete determination of dimension five operators in the superpotential arising from the mediation of the 1-, 45- and 210-dimensional representations is also given. The vector couplings 16-bar ± 16 ± 1, 16-bar ± 16 ± 45 and 16-bar ± 16 ± 210 are also analyzed. The role of large tensor representations and the possible application of results derived here in model building are discussed

Search for beyond standard model physics (non-SUSY) in final states with photons at the Tevatron

Energy Technology Data Exchange (ETDEWEB)

Palencia, Jose Enrique; /Fermilab

2009-01-01

We present the results of searches for non-standard model phenomena in photon final states. These searches use data from integrated luminosities of {approx} 1-4 fb{sup -1} of p{bar p} collisions at {radical}s = 1.96 TeV, collected with the CDF and D0 detectors at the Fermilab Tevatron. No significant excess in data has been observed. We report limits on the parameters of several BSM models (excluding SUSY) for events containing photons.

A tick gut protein with fibronectin III domains aids Borrelia burgdorferi congregation to the gut during transmission

NARCIS (Netherlands)

Narasimhan, Sukanya; Coumou, Jeroen; Schuijt, Tim J.; Boder, Eric; Hovius, Joppe W.; Fikrig, Erol

2014-01-01

Borrelia burgdorferi transmission to the vertebrate host commences with growth of the spirochete in the tick gut and migration from the gut to the salivary glands. This complex process, involving intimate interactions of the spirochete with the gut epithelium, is pivotal to transmission. We utilized

Gut microbiota sustains hematopoiesis

DEFF Research Database (Denmark)

Theilgaard-Mönch, Kim

2017-01-01

In this issue of Blood, Josefsdottir et al provide substantial evidence that commensal gut microbes regulate and sustain normal steady-state hematopoiesis.1......In this issue of Blood, Josefsdottir et al provide substantial evidence that commensal gut microbes regulate and sustain normal steady-state hematopoiesis.1...

New Higgs Inflation in a No-Scale Supersymmetric SU(5) GUT

CERN Document Server

Ellis, John; Xianyu, Zhong-Zhi

2015-01-01

Higgs inflation is attractive because it identifies the inflaton with the electroweak Higgs boson. In this work, we construct a new class of supersymmetric Higgs inflationary models in the no-scale supergravity with an SU(5) GUT group. Extending the no-scale Kahler potential and SU(5) GUT superpotential, we derive a generic potential for Higgs inflation that includes the quadratic monomial potential and a Starobinsky-type potential as special limits. This type of models can accommodate a wide range of the tensor-to-scalar ratio $r = O(10^{-3}-10^{-1})$, as well as a scalar spectral index $n_s \\sim 0.96$.

Gut microbiome and its role in cardiovascular diseases.

Science.gov (United States)

Ahmadmehrabi, Shadi; Tang, W H Wilson

2017-11-01

In recent years, an interest in intestinal microbiota-host interactions has increased due to many findings about the impact of gut bacteria on human health and disease. Dysbiosis, a change in the composition of the gut microbiota, has been associated with much pathology, including cardiovascular diseases (CVD). This article will review normal functions of the gut microbiome, its link to CVD, and potential therapeutic interventions. The recently discovered contribution of gut microbiota-derived molecules in the development of heart disease and its risk factors has significantly increased attention towards the connection between our gut and heart. The gut microbiome is virtually an endocrine organ, arguably the largest, capable of contributing to and reacting to circulating signaling molecules within the host. Gut microbiota-host interactions occur through many pathways, including trimethylamine-N-oxide and short-chain fatty acids. These molecules and others have been linked to much pathology including chronic kidney disease, atherosclerosis, and hypertension. Although our understanding of gut microbiota-host interactions has increased recently; many questions remain about the mechanistic links between the gut microbiome and CVD. With further research, we may one day be able to add gut microbiota profiles as an assessable risk factor for CVD and target therapies towards the gut microbiota.

Search for GUT magnetic monopoles and nuclearites with the MACRO experiment

CERN Document Server

Ambrosio, M; Auriemma, G; Bakari, D; Baldini, A; Barbarino, G C; Barish, B C; Battistoni, G; Becherini, Y; Bellotti, R; Bemporad, C; Bernardini, P; Bilokon, H; Bloise, C; Bower, C; Brigida, M; Bussino, S; Cafagna, F; Calicchio, M; Campana, D; Carboni, M; Caruso, R; Cecchini, S; Cei, F; Chiarella, V; Chiarusi, T; Choudhary, B C; Coutu, S; Cozzi, M; De Cataldo, G; De Marzo, C; De Mitri, I; De Vincenzi, M; Dekhissi, H; Derkaoui, J; Di Credico, A; Erriquez, O; Favuzzi, C; Forti, C; Fusco, P; Giacomelli, G; Giannini, G; Giglietto, N; Giorgini, M; Grassi, M; Grillo, A; Guarino, F; Gustavino, C; Habig, A; Hanson, K; Heinz, R; Katsavounidis, E; Katsavounidis, I; Kearns, E; Kim, H; Kumar, A; Kyriazopoulou, S; Lamanna, E; Lane, C; Larocci, E; Levin, D S; Lipari, P; Longley, N P; Longo, M J; Loparco, F; Maarou, F; Mancarella, G; Mandrioli, G; Manzoor, S; Margiotta, A; Marini, A; Martello, D; Marzari-Chiesa, A; Matteuzzi, D; Mazziotta, M N; Michael, D G; Monacelli, P; Montaruli, T; Monteno, M; Mufson, S; Musser, J; Nicolò, D; Nolty, R; Orth, C; Osteria, G; Palamara, O; Patera, V; Patrizii, L; Pazzi, R; Peck, C W; Perrone, L; Petrera, S; Pistilli, P; Popa, V; Rainó, A; Reynoldson, J; Ronga, F; Rrhioua, A; Satriano, C; Scapparone, E; Scholberg, K; Sciubba, A; Serra, P; Sioli, M; Sirri, G; Sitta, M; Spinelli, P; Spinetti, M; Spurio, M; Steinberg, R; Stone, J L; Sulak, L R; Surdo, A; Tarle, G; Togo, V; Vakili, M; Walter, C W; Webb, R; 10.1016/S1350-4487(03)00140-9

2003-01-01

We present the final results obtained by the MACRO experiment in the search for GUT magnetic monopoles and nuclearites. Several searches were performed with different subdetectors, i.e. scintillation counters, limited streamer tubes and nuclear track detectors. No magnetic monopole or nuclearite candidates were found. The MACRO upper limit to the local flux of GUT magnetic monopoles is at the level of 1.4*10/sup -16/ cm/sup -2/s/sup -1/sr/sup -1/.

Hybrid inflation exit through tunneling

International Nuclear Information System (INIS)

Garbrecht, Bjoern; Konstandin, Thomas

2007-01-01

For hybrid inflationary potentials, we derive the tunneling rate from field configurations along the flat direction towards the waterfall regime. This process competes with the classically rolling evolution of the scalar fields and needs to be strongly subdominant for phenomenologically viable models. Tunneling may exclude models with a mass scale below 10 12 GeV, but can be suppressed by small values of the coupling constants. We find that tunneling is negligible for those models, which do not require fine tuning in order to cancel radiative corrections, in particular for GUT-scale SUSY inflation. In contrast, electroweak scale hybrid inflation is not viable, unless the inflaton-waterfall field coupling is smaller than approximately 10 -11

33 CFR 117.537 - Townsend Gut.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Townsend Gut. 117.537 Section 117... OPERATION REGULATIONS Specific Requirements Maine § 117.537 Townsend Gut. The draw of the Southport (SR27) Bridge, at mile 0.7, across Townsend Gut between Boothbay Harbor and Southport, Maine shall open on...

Microbial diversity and digestive enzyme activities in the gut of earthworms found in sawmill industries in Abeokuta, Nigeria.

Science.gov (United States)

Bamidele, Julius A; Idowu, Adewunmi B; Ademolu, Kehinde O; Atayese, Adijat O

2014-09-01

The growing demand for wood has resulted in large volumes of wood wastes that are daily released to the soil from the activities of sawmills in South-Western Nigeria. In an attempt to setup a bioremediation model for sawdust, this study therefore aimed at evaluating microbial diversity, and the level of digestive enzymes in the gut of earthworms (Eudrilus eugeniae, Libyodrilus violaceous and Hyperiodrilus africanus) of sawmill origin. Four major sawmills located in Abeokuta (7°9'12" N- 3°19'35" E), namely Lafenwa, Sapon, Isale-Ake and Kotopo sawmills were used for this study. The arboretum of the Federal University of Agriculture, Abeokuta was used as control. Gut microbial analysis was carried out using the pour-plate method while digestive enzyme activities in the earthworm guts were done by the spectrophotometric method. Higher microbial counts (28.5 ± 0.1 x 10(3)-97.0 ± 0.1 x 10(3) cfu for bacteria and 7.0 ± 0.1x 10(3)-96.0 ± 0.1 x 10(3) cfu for fungi) and microbial diversity were recorded in the gut of earthworms of the sawmill locations than those of the control site (17.5 ± 0.1 x10(3) cfu for bacteria and 4.5 ± 0.1 x 10(3) cfu for fungi). Streptococcus mutans and Proteus spp. were common in the gut of E. eugeniae, and L. violaceous from the study sawmills, while Streptococcus mutans were also identified in H. africanus, but absent in the gut of E. eugeniae from the control site. Cellulase (48.67 ± 0.02 mg/g) and lipase (1.81 ± 0.01 mg/g) activities were significantly higher (p earthworms from the control site than those of the study sawmills. Furthermore, amylase (α and β) activity was highest in the gut of earthworms from the sawmills. Variations observed in the gut microbial and digestive enzyme activities of earthworms from the study sawmills as compared to the control site suggests that earthworms, especially E. eugeniae, could be a better organism for use as bioremediator of wood wastes.

How gut transcriptional function of Drosophila melanogaster varies with the presence and composition of the gut microbiota.

Science.gov (United States)

Bost, Alyssa; Franzenburg, Soeren; Adair, Karen L; Martinson, Vincent G; Loeb, Greg; Douglas, Angela E

2018-04-01

Despite evidence from laboratory experiments that perturbation of the gut microbiota affects many traits of the animal host, our understanding of the effect of variation in microbiota composition on animals in natural populations is very limited. The core purpose of this study on the fruit fly Drosophila melanogaster was to identify the impact of natural variation in the taxonomic composition of gut bacterial communities on host traits, with the gut transcriptome as a molecular index of microbiota-responsive host traits. Use of the gut transcriptome was validated by demonstrating significant transcriptional differences between the guts of laboratory flies colonized with bacteria and maintained under axenic conditions. Wild Drosophila from six field collections made over two years had gut bacterial communities of diverse composition, dominated to varying extents by Acetobacteraceae and Enterobacteriaceae. The gut transcriptomes also varied among collections and differed markedly from those of laboratory flies. However, no overall relationship between variation in the wild fly transcriptome and taxonomic composition of the gut microbiota was evident at all taxonomic scales of bacteria tested for both individual fly genes and functional categories in Gene Ontology. We conclude that the interaction between microbiota composition and host functional traits may be confounded by uncontrolled variation in both ecological circumstance and host traits (e.g., genotype, age physiological condition) under natural conditions, and that microbiota effects on host traits identified in the laboratory should, therefore, be extrapolated to field population with great caution. © 2017 John Wiley & Sons Ltd.

Gut immunity in Lepidopteran insects.

Science.gov (United States)

Wu, Kai; Yang, Bing; Huang, Wuren; Dobens, Leonard; Song, Hongsheng; Ling, Erjun

2016-11-01

Lepidopteran insects constitute one of the largest fractions of animals on earth, but are considered pests in their relationship with man. Key to the success of this order of insects is its ability to digest food and absorb nutrition, which takes place in the midgut. Because environmental microorganisms can easily enter Lepidopteran guts during feeding, the innate immune response guards against pathogenic bacteria, virus and microsporidia that can be devoured with food. Gut immune responses are complicated by both resident gut microbiota and the surrounding peritrophic membrane and are distinct from immune responses in the body cavity, which depend on the function of the fat body and hemocytes. Due to their relevance to agricultural production, studies of Lepidopteran insect midgut and immunity are receiving more attention, and here we summarize gut structures and functions, and discuss how these confer immunity against different microorganisms. It is expected that increased knowledge of Lepidopteran gut immunity may be utilized for pest biological control in the future. Copyright © 2016 Elsevier Ltd. All rights reserved.

Automated calculation of sinθ{sub W} and M{sub W} from muon decay within FlexibleSUSY

Energy Technology Data Exchange (ETDEWEB)

Bach, Markus; Stoeckinger, Dominik [IKTP, TU Dresden (Germany); Voigt, Alexander [DESY, Hamburg (Germany)

2016-07-01

The spectrum generator generator FlexibleSUSY can be utilized to investigate a variety of supersymmetric and non-supersymmetric models. We present an implementation which calculates the weak mixing angle from the precisely measured muon decay, especially taking vertex and box diagram corrections of the respective model into account. This framework also offers a prediction of the W boson mass which can be compared to the experimental value and thus used to exclude parameter regions.

Broad spectrum antibiotic enrofloxacin modulates contact sensitivity through gut microbiota in a murine model.

Science.gov (United States)

Strzępa, Anna; Majewska-Szczepanik, Monika; Lobo, Francis M; Wen, Li; Szczepanik, Marian

2017-07-01

Medical advances in the field of infection therapy have led to an increasing use of antibiotics, which, apart from eliminating pathogens, also partially eliminate naturally existing commensal bacteria. It has become increasingly clear that less exposure to microbiota early in life may contribute to the observed rise in "immune-mediated" diseases, including autoimmunity and allergy. We sought to test whether the change of gut microbiota with the broad spectrum antibiotic enrofloxacin will modulate contact sensitivity (CS) in mice. Natural gut microbiota were modified by oral treatment with enrofloxacin prior to sensitization with trinitrophenyl chloride followed by CS testing. Finally, adoptive cell transfers were performed to characterize the regulatory cells that are induced by microbiota modification. Oral treatment with enrofloxacin suppresses CS and production of anti-trinitrophenyl chloride IgG1 antibodies. Adoptive transfer experiments show that antibiotic administration favors induction of regulatory cells that suppress CS. Flow cytometry and adoptive transfer of purified cells show that antibiotic-induced suppression of CS is mediated by TCR αβ + CD4 + CD25 + FoxP3 + Treg, CD19 + B220 + CD5 + IL-10 + , IL-10 + Tr1, and IL-10 + TCR γδ + cells. Treatment with the antibiotic induces dysbiosis characterized by increased proportion of Clostridium coccoides (cluster XIVa), C coccoides-Eubacterium rectale (cluster XIVab), Bacteroidetes, and Bifidobacterium spp, but decreased segmented filamentous bacteria. Transfer of antibiotic-modified gut microbiota inhibits CS, but this response can be restored through oral transfer of control gut bacteria to antibiotic-treated animals. Oral treatment with a broad spectrum antibiotic modifies gut microbiota composition and promotes anti-inflammatory response, suggesting that manipulation of gut microbiota can be a powerful tool to modulate the course of CS. Copyright © 2017 American Academy of Allergy, Asthma & Immunology

Healthy human gut phageome.

Science.gov (United States)

Manrique, Pilar; Bolduc, Benjamin; Walk, Seth T; van der Oost, John; de Vos, Willem M; Young, Mark J

2016-09-13

The role of bacteriophages in influencing the structure and function of the healthy human gut microbiome is unknown. With few exceptions, previous studies have found a high level of heterogeneity in bacteriophages from healthy individuals. To better estimate and identify the shared phageome of humans, we analyzed a deep DNA sequence dataset of active bacteriophages and available metagenomic datasets of the gut bacteriophage community from healthy individuals. We found 23 shared bacteriophages in more than one-half of 64 healthy individuals from around the world. These shared bacteriophages were found in a significantly smaller percentage of individuals with gastrointestinal/irritable bowel disease. A network analysis identified 44 bacteriophage groups of which 9 (20%) were shared in more than one-half of all 64 individuals. These results provide strong evidence of a healthy gut phageome (HGP) in humans. The bacteriophage community in the human gut is a mixture of three classes: a set of core bacteriophages shared among more than one-half of all people, a common set of bacteriophages found in 20-50% of individuals, and a set of bacteriophages that are either rarely shared or unique to a person. We propose that the core and common bacteriophage communities are globally distributed and comprise the HGP, which plays an important role in maintaining gut microbiome structure/function and thereby contributes significantly to human health.

Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota.

Science.gov (United States)

Peterson, C T; Sharma, V; Elmén, L; Peterson, S N

2015-03-01

The distal gut harbours ∼10(13) bacteria, representing the most densely populated ecosystem known. The functional diversity expressed by these communities is enormous and relatively unexplored. The past decade of research has unveiled the profound influence that the resident microbial populations bestow to host immunity and metabolism. The evolution of these communities from birth generates a highly adapted and highly personalized microbiota that is stable in healthy individuals. Immune homeostasis is achieved and maintained due in part to the extensive interplay between the gut microbiota and host mucosal immune system. Imbalances of gut microbiota may lead to a number of pathologies such as obesity, type I and type II diabetes, inflammatory bowel disease (IBD), colorectal cancer (CRC) and inflammaging/immunosenscence in the elderly. In-depth understanding of the underlying mechanisms that control homeostasis and dysbiosis of the gut microbiota represents an important step in our ability to reliably modulate the gut microbiota with positive clinical outcomes. The potential of microbiome-based therapeutics to treat epidemic human disease is of great interest. New therapeutic paradigms, including second-generation personalized probiotics, prebiotics, narrow spectrum antibiotic treatment and faecal microbiome transplantation, may provide safer and natural alternatives to traditional clinical interventions for chronic diseases. This review discusses host-microbiota homeostasis, consequences of its perturbation and the associated challenges in therapeutic developments that lie ahead. © 2014 British Society for Immunology.

Brain Gut Microbiome Interactions and Functional Bowel Disorders