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Sample records for sustainable proton shuttle

  1. Proton shuttles and phosphatase activity in soluble epoxide hydrolase.

    Science.gov (United States)

    De Vivo, Marco; Ensing, Bernd; Dal Peraro, Matteo; Gomez, German A; Christianson, David W; Klein, Michael L

    2007-01-17

    Recently, a novel metal Mg2+-dependent phosphatase activity has been discovered in the N-terminal domain of the soluble epoxide hydrolase (sEH), opening a new branch of fatty acid metabolism and providing an additional site for drug targeting. Importantly, the sEH N-terminal fold belongs to the haloacid dehalogenase (HAD) superfamily, which comprises a vast majority of phosphotransferases. Herein, we present the results of a computational study of the sEH phosphatase activity, which includes classical molecular dynamics (MD) simulations and mixed quantum mechanical/molecular mechanics (QM/MM) calculations. On the basis of experimental results, a two-step mechanism has been proposed and herein investigated: (1) phosphoenzyme intermediate formation and (2) phosphoenzyme intermediate hydrolysis. Building on our earlier work, we now provide a detailed description of the reaction mechanism for the whole catalytic cycle along with its free energy profile. The present computations suggest metaphosphate-like transition states for these phosphoryl transfers. They also reveal that the enzyme promotes water deprotonation and facilitates shuttling of protons via a metal-ligand connecting water bridge (WB). These WB-mediated proton shuttles are crucial for the activation of the solvent nucleophile and for the stabilization of the leaving group. Moreover, due to the conservation of structural features in the N-terminal catalytic site of sEH and other members of the HAD superfamily, we suggest a generalization of our findings to these other metal-dependent phosphatases.

  2. Proton Exchange Membrane (PEM) fuel Cell for Space Shuttle

    Science.gov (United States)

    Hoffman, William C., III; Vasquez, Arturo; Lazaroff, Scott M.; Downey, Michael G.

    1999-01-01

    Development of a PEM fuel cell powerplant (PFCP) for use in the Space Shuttle offers multiple benefits to NASA. A PFCP with a longer design life than is delivered currently from the alkaline fuel will reduce Space Shuttle Program maintenance costs. A PFCP compatible with zero-gravity can be adapted for future NASA transportation and exploration programs. Also, the commercial PEM fuel cell industry ensures a competitive environment for select powerplant components. Conceptual designs of the Space Shuttle PFCP have resulted in identification of key technical areas requiring resolution prior to development of a flight system. Those technical areas include characterization of PEM fuel cell stack durability under operational conditions and water management both within and external to the stack. Resolution of the above issues is necessary to adequately control development, production, and maintenance costs for a PFCP.

  3. Polarity governed selective amplification of through plane proton shuttling in proton exchange membrane fuel cells.

    Science.gov (United States)

    Gautam, Manu; Chattanahalli Devendrachari, Mruthyunjayachari; Thimmappa, Ravikumar; Raja Kottaichamy, Alagar; Pottachola Shafi, Shahid; Gaikwad, Pramod; Makri Nimbegondi Kotresh, Harish; Ottakam Thotiyl, Musthafa

    2017-03-15

    Graphene oxide (GO) anisotropically conducts protons with directional dominance of in plane ionic transport (σ IP) over the through plane (σ TP). In a typical H 2 -O 2 fuel cell, since the proton conduction occurs through the plane during its generation at the fuel electrode, it is indeed inevitable to selectively accelerate GO's σ TP for advancement towards a potential fuel cell membrane. We successfully achieved ∼7 times selective amplification of GO's σ TP by tuning the polarity of the dopant molecule in its nanoporous matrix. The coexistence of strongly non-polar and polar domains in the dopant demonstrated a synergistic effect towards σ TP with the former decreasing the number of water molecules coordinated to protons by ∼3 times, diminishing the effects of electroosmotic drag exerted on ionic movements, and the latter selectively accelerating σ TP across the catalytic layers by bridging the individual GO planes via extensive host guest H-bonding interactions. When they are decoupled, the dopant with mainly non-polar or polar features only marginally enhances the σ TP, revealing that polarity factors contribute to fuel cell relevant transport properties of GO membranes only when they coexist. Fuel cell polarization and kinetic analyses revealed that these multitask dopants increased the fuel cell performance metrics of the power and current densities by ∼3 times compared to the pure GO membranes, suggesting that the functional group factors of the dopants are of utmost importance in GO-based proton exchange membrane fuel cells.

  4. Experimental and Computational Study of an Unexpected Iron-Catalyzed Carboetherification by Cooperative Metal and Ligand Substrate Interaction and Proton Shuttling

    KAUST Repository

    El-Sepelgy, Osama

    2017-09-26

    An iron-catalyzed cycloisomerization of allenols to deoxygenated pyranose glycals has been developed. Combined experimental and computational studies show that the iron complex exhibits a dual catalytic role in that the non-innocent cyclopentadienone ligand acts as proton shuttle by initial hydrogen abstraction from the alcohol and by facilitating protonation and deprotonation events in the isomerization and demetalation steps. Molecular orbital analysis provides insight into the unexpected and selective formation of the 3,4-dihydro-2H-pyran.

  5. Proton Shuttling and Reaction Paths in Dissociative Electron Attachment to o- and p-Tetrafluorohydroquinone, an Experimental and Theoretical Study.

    Science.gov (United States)

    Ómarsson, Benedikt; Bjornsson, Ragnar; Ingólfsson, Oddur

    2017-08-03

    Here we present a combined experimental and theoretical study on the fragmentation of o- and p-tetrafluorohydroquinone upon low energy electron attachment. Despite an identical ring-skeleton and identical functional groups in these constitutional isomers, they show distinctly different fragmentation patterns, a phenomenon that cannot be explained by distinct resonances or different thermochemistry. Using high-level quantum chemical calculations with the computationally affordable domain localized pair natural orbital approach, DLPNO-CCSD(T), we are able to provide a complete and accurate description of the respective reaction dynamics, revealing proton shuttling and transition states for competing channels as the explanation for the different behavior of these isomers. The results represent a "schoolbook example" of how the combination of experiment and modern high-level theory may today provide a thorough understanding of complex reaction dynamics by computationally affordable means.

  6. Shuttle Shortfalls and Lessons Learned for the Sustainment of Human Space Exploration

    Science.gov (United States)

    Zapata, Edgar; Levack, Daniel J. H.; Rhodes, Russell E.; Robinson, John W.

    2009-01-01

    Much debate and national soul searching has taken place over the value of the Space Shuttle which first flew in 1981 and which is currently scheduled to be retired in 2010. Originally developed post-Saturn Apollo to emphasize affordability and safety, the reusable Space Shuttle instead came to be perceived as economically unsustainable and lacking the technology maturity to assure safe, routine access to low earth orbit (LEO). After the loss of two crews, aboard Challenger and Columbia, followed by the decision to retire the system in 2010, it is critical that this three decades worth of human space flight experience be well understood. Understanding of the past is imperative to further those goals for which the Space Shuttle was a stepping-stone in the advancement of knowledge. There was significant reduction in life cycle costs between the Saturn Apollo and the Space Shuttle. However, the advancement in life cycle cost reduction from Saturn Apollo to the Space Shuttle fell far short of its goal. This paper will explore the reasons for this shortfall. Shortfalls and lessons learned can be categorized as related to design factors, at the architecture, element and sub-system levels, as well as to programmatic factors, in terms of goals, requirements, management and organization. Additionally, no review of the Space Shuttle program and attempt to take away key lessons would be complete without a strategic review. That is, how do national space goals drive future space transportation development strategies? The lessons of the Space Shuttle are invaluable in all respects - technical, as in design, program-wise, as in organizational approach and goal setting, and strategically, within the context of the generational march toward an expanded human presence in space. Beyond lessons though (and the innumerable papers, anecdotes and opinions published on this topic) this paper traces tangible, achievable steps, derived from the Space Shuttle program experience, that must be

  7. A self-sustained, complete and miniaturized methanol fuel processor for proton exchange membrane fuel cell

    Science.gov (United States)

    Yang, Mei; Jiao, Fengjun; Li, Shulian; Li, Hengqiang; Chen, Guangwen

    2015-08-01

    A self-sustained, complete and miniaturized methanol fuel processor has been developed based on modular integration and microreactor technology. The fuel processor is comprised of one methanol oxidative reformer, one methanol combustor and one two-stage CO preferential oxidation unit. Microchannel heat exchanger is employed to recover heat from hot stream, miniaturize system size and thus achieve high energy utilization efficiency. By optimized thermal management and proper operation parameter control, the fuel processor can start up in 10 min at room temperature without external heating. A self-sustained state is achieved with H2 production rate of 0.99 Nm3 h-1 and extremely low CO content below 25 ppm. This amount of H2 is sufficient to supply a 1 kWe proton exchange membrane fuel cell. The corresponding thermal efficiency of whole processor is higher than 86%. The size and weight of the assembled reactors integrated with microchannel heat exchangers are 1.4 L and 5.3 kg, respectively, demonstrating a very compact construction of the fuel processor.

  8. Electrocatalytic Water Oxidation by a Water-Soluble Copper(II) Complex with a Copper-Bound Carbonate Group Acting as a Potential Proton Shuttle.

    Science.gov (United States)

    Chen, Fangfang; Wang, Ni; Lei, Haitao; Guo, Dingyi; Liu, Hongfei; Zhang, Zongyao; Zhang, Wei; Lai, Wenzhen; Cao, Rui

    2017-11-06

    Water-soluble copper(II) complexes of the dianionic tridentate pincer ligand N,N'-2,6-dimethylphenyl-2,6-pyridinedicarboxamidate (L) are catalysts for water oxidation. In [L-Cu II -DMF] (1, DMF = dimethylformamide) and [L-Cu II -OAc] - (2, OAc = acetate), ligand L binds Cu II through three N atoms, which define an equatorial plane. The fourth coordination site of the equatorial plane is occupied by DMF in 1 and by OAc - in 2. These two complexes can electrocatalyze water oxidation to evolve O 2 in 0.1 M pH 10 carbonate buffer. Spectroscopic, titration, and crystallographic studies show that both 1 and 2 undergo ligand exchange when they are dissolved in carbonate buffer to give [L-Cu II -CO 3 H] - (3). Complex 3 has a similar structure as those of 1 and 2 except for having a carbonate group at the fourth equatorial position. A catalytic cycle for water oxidation by 3 is proposed based on experimental and theoretical results. The two-electron oxidized form of 3 is the catalytically active species for water oxidation. Importantly, for these two oxidation events, the calculated potential values of E p,a = 1.01 and 1.59 V vs normal hydrogen electrode (NHE) agree well with the experimental values of E p,a = 0.93 and 1.51 V vs NHE in pH 10 carbonate buffer. The potential difference between the two oxidation events is 0.58 V for both experimental and calculated results. With computational evidence, this Cu-bound carbonate group may act as a proton shuttle to remove protons for water activation, a key role resembling intramolecular bases as reported previously.

  9. Sustainable power generation in microbial fuel cells using bicarbonate buffer and proton transfer mechanisms.

    Science.gov (United States)

    Fan, Yanzhen; Hu, Hongqiang; Liu, Hong

    2007-12-01

    Phosphate buffer solution has been commonly used in MFC studiesto maintain a suitable pH for electricity-generating bacteria and/or to increase the solution conductivity. However, addition of a high concentration of phosphate buffer in MFCs could be expensive, especially for wastewater treatment. In this study, the performances of MFCs with cloth electrode assemblies (CEA) were evaluated using bicarbonate buffer solutions. A maximum power density of 1550 W/m3 (2770 mW/ m2) was obtained at a current density of 0.99 mA/cm2 using a pH 9 bicarbonate buffer solution. Such a power density was 38.6% higher than that using a pH 7 phosphate buffer at the same concentration of 0.2 M. Based on the quantitative comparison of free proton transfer rates, diffusion rates of pH buffer species, and the current generated, a facilitated proton transfer mechanism was proposed for MFCs in the presence of the pH buffers. The excellent performance of MFCs using bicarbonate as pH buffer and proton carrier indicates that bicarbonate buffer could be served as a low-cost and effective pH buffer for practical applications, especially for wastewater treatment.

  10. Catalytic mechanisms of direct pyrrole synthesis via dehydrogenative coupling mediated by PNP-Ir or PNN-Ru pincer complexes: Crucial role of proton-transfer shuttles in the PNP-Ir system

    KAUST Repository

    Qu, Shuanglin

    2014-04-02

    Kempe et al. and Milstein et al. have recently advanced the dehydrogenative coupling methodology to synthesize pyrroles from secondary alcohols (e.g., 3) and β-amino alcohols (e.g., 4), using PNP-Ir (1) and PNN-Ru (2) pincer complexes, respectively. We herein present a DFT study to characterize the catalytic mechanism of these reactions. After precatalyst activation to give active 1A/2A, the transformation proceeds via four stages: 1A/2A-catalyzed alcohol (3) dehydrogenation to give ketone (11), base-facilitated C-N coupling of 11 and 4 to form an imine-alcohol intermediate (18), base-promoted cyclization of 18, and catalyst regeneration via H2 release from 1R/2R. For alcohol dehydrogenations, the bifunctional double hydrogen-transfer pathway is more favorable than that via β-hydride elimination. Generally, proton-transfer (H-transfer) shuttles facilitate various H-transfer processes in both systems. Notwithstanding, H-transfer shuttles play a much more crucial role in the PNP-Ir system than in the PNN-Ru system. Without H-transfer shuttles, the key barriers up to 45.9 kcal/mol in PNP-Ir system are too high to be accessible, while the corresponding barriers (<32.0 kcal/mol) in PNN-Ru system are not unreachable. Another significant difference between the two systems is that the addition of alcohol to 1A giving an alkoxo complex is endergonic by 8.1 kcal/mol, whereas the addition to 2A is exergonic by 8.9 kcal/mol. The thermodynamic difference could be the main reason for PNP-Ir system requiring lower catalyst loading than the PNN-Ru system. We discuss how the differences are resulted in terms of electronic and geometric structures of the catalysts and how to use the features in catalyst development. © 2014 American Chemical Society.

  11. Deficits in Sustained Attention and Changes in Dopaminergic Protein Levels following Exposure to Proton Radiation Are Related to Basal Dopaminergic Function.

    Directory of Open Access Journals (Sweden)

    Catherine M Davis

    Full Text Available The current report assessed the effects of low-level proton irradiation in inbred adult male Fischer 344 and Lewis rats performing an analog of the human Psychomotor Vigilance Test (PVT, commonly utilized as an object risk assessment tool to quantify fatigue and sustained attention in laboratory, clinical, and operational settings. These strains were used to determine if genetic differences in dopaminergic function would impact radiation-induced deficits in sustained attention. Exposure to head-only proton irradiation (25 or 100 cGy disrupted rPVT performance in a strain-specific manner, with 25 cGy-exposed Fischer 344 rats displaying the most severe deficits in sustained attention (i.e., decreased accuracy and increased premature responding; Lewis rats did not display behavioral deficits following radiation. Fischer 344 rats displayed greater tyrosine hydroxylase and dopamine transporter levels in the frontal cortex compared to the Lewis rats, even though radiation exposure increased both of these proteins in the Lewis rats only. Tyrosine hydroxylase was decreased in the parietal cortex of both rat strains following radiation exposure, regardless of proton dose. Strain-specific cytokine changes were also found in the frontal cortex, with the Lewis rats displaying increased levels of putative neurotrophic cytokines (e.g., CNTF. These data support the hypothesis that basal dopaminergic function impacts the severity of radiation-induced deficits in sustained attention.

  12. Shuttle requests

    CERN Multimedia

    2007-01-01

    Please note that starting from 1 March 2007, the shuttle requests: for official visits or bidders' conferences on the CERN site; towards/from the airport or central Geneva; for long distances, shall be made via Fm.Support@cern.ch or by calling 77777. The radio taxi will still be reachable at 76969. TS/FM Group

  13. CERN Shuttle

    CERN Document Server

    General Infrastructure Services Department

    2011-01-01

    As of Monday 21 February, a new schedule will come into effect for the Airport Shuttle (circuit No. 4) at the end of the afternoon: Last departure at 7:00 pm from Main Buildig, (Bldg. 500) to Airport (instead of 5:10 p.m.); Last departure from Airport to CERN, Main Buildig, (Bldg. 500), at 7:30 p.m. (instead of 5:40 p.m.). Group GS-IS

  14. Shuttle requests

    CERN Multimedia

    2007-01-01

    Please note that, to improve the service we provide, a new telephone number - 72500 - has been set up for all shuttle requests concerning: journeys within the CERN site, i.e. official visits or bidders' conferences; journeys to or from the airport or city centre; long-distance journeys. However, it will still be possible to submit requests in writing to Fm.Support@cern. The radio taxi can also still be reached on 76969. The TS/FM group would also like to inform you that details of all light logistics services (transport of persons, distribution and collection of parcels up to 1 tonne, distribution and collection of mail) can be found on the group's website: http://ts-dep.web.cern.ch/ts-dep/groups/fm/fm.htm TS/FM Group 160239

  15. Proton therapy

    Science.gov (United States)

    Proton beam therapy; Cancer - proton therapy; Radiation therapy - proton therapy; Prostate cancer - proton therapy ... that use x-rays to destroy cancer cells, proton therapy uses a beam of special particles called ...

  16. Extended findings of Brain Metabolite Normalization in MA-Dependent Subjects Across Sustained Abstinence: A Proton MRS Study

    Science.gov (United States)

    Salo, Ruth; Buonocore, Michael H.; Leamon, Martin; Natsuaki, Yutaka; Waters, Christy; Moore, Charles D.; Galloway, Gantt P.; Nordahl, Thomas E.

    2010-01-01

    Objective The goal of the present study was to extend our previous findings on long-term methamphetamine (MA) use and drug abstinence on brain metabolite levels in an expanded group of MA-dependent individuals. Methods Seventeen MA abusers with sustained drug abstinence (1 year to 5 years), 30 MA abusers with short-term drug abstinence (1 month to 6 months) and 24 non-substance using controls were studied using MR spectroscopy (MRS). MRS measures of NAA/Cr, Cho/Cr and Cho/NAA were obtained in the anterior cingulate cortex (ACC) and in the primary visual cortex (PVC). Results ACC-Cho/NAA values were abnormally high in the short-term abstinent group compared to controls [F(1,52)=18.76, p<0.0001]. No differences were observed between controls and the long-term abstinent group [F(1,39)=0.97, p=0.97]. New evidence of lower ACC-NAA/Cr levels were observed in the short-term abstinent MA abusers compared to controls [F(1,52)=23.05, p<0.0001] and long-term abstinent MA abusers [F(1,45)=7.06, p=0.01]. No differences were observed between long-term abstinent MA abusers and controls [F(1,39)=0.48, p=0.49]. Conclusions The new findings of relative NAA/Cr normalization across periods of abstinence suggest that adaptive changes following cessation of MA abuse may be broader than initially thought. These changes may contribute to some degree of normalization of neuronal function in the ACC. PMID:20739127

  17. Protons and how they are transported by proton pumps

    DEFF Research Database (Denmark)

    Buch-Pedersen, Morten Jeppe; Pedersen, Bjørn Panyella; Nissen, Poul

    2008-01-01

    The very high mobility of protons in aqueous solutions demands special features of membrane proton transporters to sustain efficient yet regulated proton transport across biological membranes. By the use of the chemical energy of ATP, plasma-membrane-embedded ATPases extrude protons from cells...... of plants and fungi to generate electrochemical proton gradients. The recently published crystal structure of a plasma membrane H(+)-ATPase contributes to our knowledge about the mechanism of these essential enzymes. Taking the biochemical and structural data together, we are now able to describe the basic...... molecular components that allow the plasma membrane proton H(+)-ATPase to carry out proton transport against large membrane potentials. When divergent proton pumps such as the plasma membrane H(+)-ATPase, bacteriorhodopsin, and F(O)F(1) ATP synthase are compared, unifying mechanistic premises for biological...

  18. Protons and how they are transported by proton pumps.

    Science.gov (United States)

    Buch-Pedersen, M J; Pedersen, B P; Veierskov, B; Nissen, P; Palmgren, M G

    2009-01-01

    The very high mobility of protons in aqueous solutions demands special features of membrane proton transporters to sustain efficient yet regulated proton transport across biological membranes. By the use of the chemical energy of ATP, plasma-membrane-embedded ATPases extrude protons from cells of plants and fungi to generate electrochemical proton gradients. The recently published crystal structure of a plasma membrane H(+)-ATPase contributes to our knowledge about the mechanism of these essential enzymes. Taking the biochemical and structural data together, we are now able to describe the basic molecular components that allow the plasma membrane proton H(+)-ATPase to carry out proton transport against large membrane potentials. When divergent proton pumps such as the plasma membrane H(+)-ATPase, bacteriorhodopsin, and F(O)F(1) ATP synthase are compared, unifying mechanistic premises for biological proton pumps emerge. Most notably, the minimal pumping apparatus of all pumps consists of a central proton acceptor/donor, a positively charged residue to control pK(a) changes of the proton acceptor/donor, and bound water molecules to facilitate rapid proton transport along proton wires.

  19. Shuttle Wastewater Solution Characterization

    Science.gov (United States)

    Adam, Niklas; Pham, Chau

    2011-01-01

    During the 31st shuttle mission to the International Space Station, STS-129, there was a clogging event in the shuttle wastewater tank. A routine wastewater dump was performed during the mission and before the dump was completed, degraded flow was observed. In order to complete the wastewater dump, flow had to be rerouted around the dump filter. As a result, a basic chemical and microbial investigation was performed to understand the shuttle wastewater system and perform mitigation tasks to prevent another blockage. Testing continued on the remaining shuttle flights wastewater and wastewater tank cleaning solutions. The results of the analyses and the effect of the mitigation steps are detailed in this paper.

  20. Space Shuttle-Illustration

    Science.gov (United States)

    2001-01-01

    The Space Shuttle represented an entirely new generation of space vehicles, the world's first reusable spacecraft. Unlike earlier expendable rockets, the Shuttle was designed to be launched over and over again and would serve as a system for ferrying payloads and persornel to and from Earth orbit. The Shuttle's major components are the orbiter spacecraft; the three main engines, with a combined thrust of more than 1.2 million pounds; the huge external tank (ET) that feeds the liquid hydrogen fuel and liquid oxygen oxidizer to the three main engines; and the two solid rocket boosters (SRB's), with their combined thrust of some 5.8 million pounds, that provide most of the power for the first two minutes of flight. Crucially involved with the Space Shuttle program virtually from its inception, the Marshall Space Flight Center (MSFC) played a leading role in the design, development, testing, and fabrication of many major Shuttle propulsion components. The MSFC was assigned responsibility for developing the Shuttle orbiter's high-performance main engines, the most complex rocket engines ever built. The MSFC was also responsible for developing the Shuttle's massive ET and the solid rocket motors and boosters.

  1. Enhancement of proton conductance by mutations of the selectivity filter of aquaporin-1

    DEFF Research Database (Denmark)

    Li, Hui; Chen, Hanning; Steinbronn, Christina

    2011-01-01

    mechanism, a model "classical" charge localized hydronium cation that exhibits no Grotthuss shuttling, and a sodium cation. The hydrated excess proton was simulated using a specialized multi-state molecular dynamics method including a proper physical treatment of the proton shuttling and charge defect...

  2. Space Shuttle Abort Evolution

    Science.gov (United States)

    Henderson, Edward M.; Nguyen, Tri X.

    2011-01-01

    This paper documents some of the evolutionary steps in developing a rigorous Space Shuttle launch abort capability. The paper addresses the abort strategy during the design and development and how it evolved during Shuttle flight operations. The Space Shuttle Program made numerous adjustments in both the flight hardware and software as the knowledge of the actual flight environment grew. When failures occurred, corrections and improvements were made to avoid a reoccurrence and to provide added capability for crew survival. Finally some lessons learned are summarized for future human launch vehicle designers to consider.

  3. Protons in near earth orbit

    CERN Document Server

    Alcaraz, J; Alpat, B; Ambrosi, G; Anderhub, H; Ao, L; Arefev, A; Azzarello, P; Babucci, E; Baldini, L; Basile, M; Barancourt, D; Barão, F; Barbier, G; Barreira, G; Battiston, R; Becker, R; Becker, U; Bellagamba, L; Béné, P; Berdugo, J; Berges, P; Bertucci, B; Biland, A; Bizzaglia, S; Blasko, S; Bölla, G; Boschini, M; Bourquin, Maurice; Bruni, G; Buénerd, M; Burger, J D; Burger, W J; Cai, X D; Cavalletti, R; Camps, C; Cannarsa, P; Capell, M; Casadei, D; Casaus, J; Castellini, G; Chang, Y H; Chen, H F; Chen, H S; Chen, Z G; Chernoplekov, N A; Chiarini, A; Tzi Hong Chiueh; Chuang, Y L; Cindolo, F; Commichau, V; Contin, A; Cotta-Ramusino, A; Crespo, P; Cristinziani, M; Da Cunha, J P; Dai, T S; Deus, J D; Dinu, N; Djambazov, L; D'Antone, I; Dong, Z R; Emonet, P; Engelberg, J; Eppling, F J; Eronen, T; Esposito, G; Extermann, Pierre; Favier, Jean; Feng, C C; Fiandrini, E; Finelli, F; Fisher, P H; Flaminio, R; Flügge, G; Fouque, N; Galaktionov, Yu; Gervasi, M; Giusti, P; Grandi, D; Gu, W Q; Hangarter, K; Hasan, A; Hermel, V; Hofer, H; Huang, M A; Hungerford, W; Ionica, M; Ionica, R; Jongmanns, M; Karlamaa, K; Karpinski, W; Kenney, G; Kenny, J; Kim, W; Klimentov, A; Kossakowski, R; Koutsenko, V F; Laborie, G; Laitinen, T; Lamanna, G; Laurenti, G; Lebedev, A; Lee, S C; Levi, G; Levchenko, P M; Liu, C L; Liu Hong Tao; Lolli, M; Lopes, I; Lu, G; Lü, Y S; Lübelsmeyer, K; Luckey, D; Lustermann, W; Maña, C; Margotti, A; Massera, F; Mayet, F; McNeil, R R; Meillon, B; Menichelli, M; Mezzanotte, F; Mezzenga, R; Mihul, A; Molinari, G; Mourão, A M; Mujunen, A; Palmonari, F; Pancaldi, G; Papi, A; Park, I H; Pauluzzi, M; Pauss, Felicitas; Perrin, E; Pesci, A; Pevsner, A; Pilastrini, R; Pimenta, M; Plyaskin, V; Pozhidaev, V; Postema, H; Postolache, V; Prati, E; Produit, N; Rancoita, P G; Rapin, D; Raupach, F; Recupero, S; Ren, D; Ren, Z; Ribordy, M; Richeux, J P; Riihonen, E; Ritakari, J; Röser, U; Roissin, C; Sagdeev, R; Santos, D; Sartorelli, G; Schultz von Dratzig, A; Schwering, G; Seo, E S; Shoutko, V; Shoumilov, E; Siedling, R; Son, D; Song, T; Steuer, M; Sun, G S; Suter, H; Tang, X W; Ting, Samuel C C; Ting, S M; Tornikoski, M; Torromeo, G; Torsti, J; Trümper, J E; Ulbricht, J; Urpo, S; Usoskin, I; Valtonen, E; Van den Hirtz, J; Velcea, F; Velikhov, E P; Verlaat, B; Vetlitskii, I; Vezzu, F; Vialle, J P; Viertel, Gert M; Vitè, Davide F; Von Gunten, H P; Waldmeier-Wicki, S; Wallraff, W; Wang, B C; Wang, J Z; Wang, Y H; Wiik, K; Williams, C; Wu, S X; Xia, P C; Yan, J L; Yan Lu Guang; Yang, C G; Yang, M; Ye Shu Wei; Yeh, P; Xu, Z Z; Zhang, H Y; Zhang, Z P; Zhao, D X; Zhu, G Y; Zhu, W Z; Zhuang, H L; Zichichi, A

    2000-01-01

    The proton spectrum in the kinetic energy range 0.1 to 200 GeV was measuredby the Alpha Magnetic Spectrometer (AMS) during space shuttle flight STS-91 atan altitude of 380 km. Above the geomagnetic cutoff the observed spectrum isparameterized by a power law. Below the geomagnetic cutoff a substantial secondspectrum was observed concentrated at equatorial latitudes with a flux ~ 70m^-2 sec^-1 sr^-1. Most of these second spectrum protons follow a complicatedtrajectory and originate from a restricted geographic region.

  4. Shuttle Inventory Management

    Science.gov (United States)

    1983-01-01

    Inventory Management System (SIMS) consists of series of integrated support programs providing supply support for both Shuttle program and Kennedy Space Center base opeations SIMS controls all supply activities and requirements from single point. Programs written in COBOL.

  5. Space Shuttle: The Renewed Promise.

    Science.gov (United States)

    McAleer, Neil

    This booklet describes the history of the space shuttle, especially after the Challenger accident. Topics include: (1) "Introduction"; (2) "Return to Flight: The Recovery"; (3) "Space Shuttle Chronology"; (4) "Examples of Other Modifications on Shuttle's Major Systems"; (5) "Space Shuttle Recovery…

  6. Stretching the Shuttle

    Science.gov (United States)

    Furniss, Tim

    1992-05-01

    A review is presented of the modifications incorporated in the Shuttle Columbia to extend its duration and capabilities in preparation for this extended-duration orbiter (EDO) to fly missions of up to 16 days. Attention is given to the evolution of the program that has changed the Shuttle from a space truck on nominal seven-day sorties to a versatile vehicle that can perform as a space laboratory. Consideration is given to the provision of more electrical power and life support supplies and equipment, the CRYO wafer pallet, advanced general-purpose computers, and an improved radar-altimeter.

  7. Nanoparticle shuttle memory

    Science.gov (United States)

    Zettl, Alex Karlwalter [Kensington, CA

    2012-03-06

    A device for storing data using nanoparticle shuttle memory having a nanotube. The nanotube has a first end and a second end. A first electrode is electrically connected to the first end of the nanotube. A second electrode is electrically connected to the second end of the nanotube. The nanotube has an enclosed nanoparticle shuttle. A switched voltage source is electrically connected to the first electrode and the second electrode, whereby a voltage may be controllably applied across the nanotube. A resistance meter is also connected to the first electrode and the second electrode, whereby the electrical resistance across the nanotube can be determined.

  8. Protonated nitrosamide

    DEFF Research Database (Denmark)

    Egsgaard, H.; Carlsen, L.; Øgaard Madsen, J.

    1994-01-01

    The protonated nitrosamide, NH3NO+, has been generated by chemical ionization mass spectrometry. Although a direct search for this species in ammonia flames has proved negative, fast proton transfer to major flame constituents is supported experimentally as well as by MO calculations....

  9. Proton Therapy

    Science.gov (United States)

    ... therapy is one of the most precise and advanced forms of radiation treatment available. How Proton Therapy is Delivered The patient is positioned on a table with a head frame or face mask covering the head. As the cyclotron smashes atoms, the protons released are directed toward ...

  10. Hydrated Excess Protons Can Create Their Own Water Wires.

    Science.gov (United States)

    Peng, Yuxing; Swanson, Jessica M J; Kang, Seung-gu; Zhou, Ruhong; Voth, Gregory A

    2015-07-23

    Grotthuss shuttling of an excess proton charge defect through hydrogen bonded water networks has long been the focus of theoretical and experimental studies. In this work we show that there is a related process in which water molecules move ("shuttle") through a hydrated excess proton charge defect in order to wet the path ahead for subsequent proton charge migration. This process is illustrated through reactive molecular dynamics simulations of proton transport through a hydrophobic nanotube, which penetrates through a hydrophobic region. Surprisingly, before the proton enters the nanotube, it starts "shooting" water molecules into the otherwise dry space via Grotthuss shuttling, effectively creating its own water wire where none existed before. As the proton enters the nanotube (by 2-3 Å), it completes the solvation process, transitioning the nanotube to the fully wet state. By contrast, other monatomic cations (e.g., K(+)) have just the opposite effect, by blocking the wetting process and making the nanotube even drier. As the dry nanotube gradually becomes wet when the proton charge defect enters it, the free energy barrier of proton permeation through the tube via Grotthuss shuttling drops significantly. This finding suggests that an important wetting mechanism may influence proton translocation in biological systems, i.e., one in which protons "create" their own water structures (water "wires") in hydrophobic spaces (e.g., protein pores) before migrating through them. An existing water wire, e.g., one seen in an X-ray crystal structure or MD simulations without an explicit excess proton, is therefore not a requirement for protons to transport through hydrophobic spaces.

  11. Mobile Christian - shuttle flight

    Science.gov (United States)

    2009-01-01

    Erin Whittle, 14, (seated) and Brianna Johnson, 14, look on as Louis Stork, 13, attempts a simulated landing of a space shuttle at StenniSphere. The young people were part of a group from Mobile Christian School in Mobile, Ala., that visited StenniSphere on April 21.

  12. Proton interrogation

    Energy Technology Data Exchange (ETDEWEB)

    Morris, Christopher L [Los Alamos National Laboratory

    2008-01-01

    Energetic proton beams may provide an attractive alternative when compared to electromagnetic and neutron beams for active interrogation of nuclear threats because: they have large fission cross sections, long mean free paths and high penetration, and proton beams can be manipulated with magnetic optics. We have measured time-dependent cross sections for delayed neutrons and gamma-rays using the 800 MeV proton beam from the Los Alamos Neutron Science Center for a set of bare and shielded targets. The results show significant signals from both unshielded and shielded nuclear materials. Results will be presented.

  13. Shuttle freezer conceptual design

    Science.gov (United States)

    Proctor, B. W.; Russell, D. J.

    1975-01-01

    A conceptual design for a kit freezer for operation onboard shuttle was developed. The freezer features a self-contained unit which can be mounted in the orbiter crew compartment and is capable of storing food at launch and returning with medical samples. Packaging schemes were investigated to provide the optimum storage capacity with a minimum weight and volume penalty. Several types of refrigeration systems were evaluated to select one which would offer the most efficient performance and lowest hazard of safety to the crew. Detailed performance data on the selected, Stirling cycle principled refrigeration unit were developed to validate the feasibility of its application to this freezer. Thermal analyses were performed to determine the adequacy of the thermal insulation to maintain the desired storage temperature with the design cooling capacity. Stress analyses were made to insure the design structure integrity could be maintained over the shuttle flight regime. A proposed prototype freezer development plan is presented.

  14. The Launch Processing System for Space Shuttle.

    Science.gov (United States)

    Springer, D. A.

    1973-01-01

    In order to reduce costs and accelerate vehicle turnaround, a single automated system will be developed to support shuttle launch site operations, replacing a multiplicity of systems used in previous programs. The Launch Processing System will provide real-time control, data analysis, and information display for the checkout, servicing, launch, landing, and refurbishment of the launch vehicles, payloads, and all ground support systems. It will also provide real-time and historical data retrieval for management and sustaining engineering (test records and procedures, logistics, configuration control, scheduling, etc.).

  15. Shuttle Lesson Learned - Toxicology

    Science.gov (United States)

    James, John T.

    2010-01-01

    This is a script for a video about toxicology and the space shuttle. The first segment is deals with dust in the space vehicle. The next segment will be about archival samples. Then we'll look at real time on-board analyzers that give us a lot of capability in terms of monitoring for combustion products and the ability to monitor volatile organics on the station. Finally we will look at other issues that are about setting limits and dealing with ground based lessons that pertain to toxicology.

  16. Stereochemistry-Dependent Proton Conduction in Proton Exchange Membrane Fuel Cells.

    Science.gov (United States)

    Thimmappa, Ravikumar; Devendrachari, Mruthyunjayachari Chattanahalli; Kottaichamy, Alagar Raja; Tiwari, Omshanker; Gaikwad, Pramod; Paswan, Bhuneshwar; Thotiyl, Musthafa Ottakam

    2016-01-12

    Graphene oxide (GO) is impermeable to H2 and O2 fuels while permitting H(+) shuttling, making it a potential candidate for proton exchange membrane fuel cells (PEMFC), albeit with a large anisotropy in their proton transport having a dominant in plane (σIP) contribution over the through plane (σTP). If GO-based membranes are ever to succeed in PEMFC, it inevitably should have a dominant through-plane proton shuttling capability (σTP), as it is the direction in which proton gets transported in a real fuel-cell configuration. Here we show that anisotropy in proton conduction in GO-based fuel cell membranes can be brought down by selectively tuning the geometric arrangement of functional groups around the dopant molecules. The results show that cis isomer causes a selective amplification of through-plane proton transport, σTP, pointing to a very strong geometry angle in ionic conduction. Intercalation of cis isomer causes significant expansion of GO (001) planes involved in σTP transport due to their mutual H-bonding interaction and efficient bridging of individual GO planes, bringing down the activation energy required for σTP, suggesting the dominance of a Grotthuss-type mechanism. This isomer-governed amplification of through-plane proton shuttling resulted in the overall boosting of fuel-cell performance, and it underlines that geometrical factors should be given prime consideration while selecting dopant molecules for bringing down the anisotropy in proton conduction and enhancing the fuel-cell performance in GO-based PEMFC.

  17. Representative shuttle evaporative heat sink

    Science.gov (United States)

    Hixon, C. W.

    1978-01-01

    The design, fabrication, and testing of a representative shuttle evaporative heat sink (RSEHS) system which vaporizes an expendable fluid to provide cooling for the shuttle heat transport fluid loop is reported. The optimized RSEHS minimum weight design meets or exceeds the shuttle flash evaporator system requirements. A cold trap which cryo-pumps flash evaporator exhaust water from the CSD vacuum chamber test facility to prevent water contamination of the chamber pumping equipment is also described.

  18. Quantum Shuttle in Phase Space

    DEFF Research Database (Denmark)

    Novotny, Tomas; Donarini, Andrea; Jauho, Antti-Pekka

    2003-01-01

    Abstract: We present a quantum theory of the shuttle instability in electronic transport through a nanostructure with a mechanical degree of freedom. A phase space formulation in terms of the Wigner function allows us to identify a crossover from the tunneling to the shuttling regime, thus...... extending the previously found classical results to the quantum domain. Further, a new dynamical regime is discovered, where the shuttling is driven exclusively by the quantum noise....

  19. LSRA with Shuttle main gear

    Science.gov (United States)

    1993-01-01

    A space shuttle landing gear system is visible between the two main landing gear components on this NASA CV-990, modified as a Landing Systems Research Aircraft. The space shuttle landing gear test unit, operated by a high-pressure hydraulic system, allowed engineers to assess and document the performance of space shuttle main and nose landing gear systems, tires and wheel assemblies, plus braking and nose wheel steering performance.

  20. Food packages for Space Shuttle

    Science.gov (United States)

    Fohey, M. F.; Sauer, R. L.; Westover, J. B.; Rockafeller, E. F.

    1978-01-01

    The paper reviews food packaging techniques used in space flight missions and describes the system developed for the Space Shuttle. Attention is directed to bite-size food cubes used in Gemini, Gemini rehydratable food packages, Apollo spoon-bowl rehydratable packages, thermostabilized flex pouch for Apollo, tear-top commercial food cans used in Skylab, polyethylene beverage containers, Skylab rehydratable food package, Space Shuttle food package configuration, duck-bill septum rehydration device, and a drinking/dispensing nozzle for Space Shuttle liquids. Constraints and testing of packaging is considered, a comparison of food package materials is presented, and typical Shuttle foods and beverages are listed.

  1. Lower Choline-Containing Metabolites/Creatine (Cr Rise and Failure to Sustain NAA/Cr Levels in the Dorsolateral Prefrontal Cortex Are Associated with Depressive Episode Recurrence under Maintenance Therapy: A Proton Magnetic Resonance Spectroscopy Retrospective Cohort Study

    Directory of Open Access Journals (Sweden)

    Neven Henigsberg

    2017-12-01

    Full Text Available BackgroundThe aim of this study was to evaluate the relationship between changes in proton magnetic resonance spectroscopy (1H-MRS parameters at the start of the index episode recovery phase and at recurrence in patients with recurrent depression who were treated with prolonged maintenance therapy.Methods1H-MRS parameters were analyzed in 48 patients with recurrent depression who required maintenance therapy with antidepressant medication prescribed by a psychiatrist and who continued with the same antidepressant during the maintenance phase, either to recurrence of depression, completion of the 10-year observation period, or the start of the withdrawal phase (tapering-off antidepressant. N-acetylaspartate (NAA, choline-containing metabolites (Cho, creatine (Cr, and glutamine/glutamate were measured at the start of the recovery phase and 6 months later.ResultsRecurrent depressive episodes occurred in 20 patients. These individuals had a smaller increase in Cho/Cr after the beginning of the recovery phase compared to the non-recurrent patient group and also exhibited a decreased NAA/Cr ratio.ConclusionSustainable NAA and increased Cho levels at the onset of the recovery phase of the index episode are early markers of antidepressant effectiveness associated with a lower risk of major depressive disorder recurrence. The NAA and Cho changes in the non-recurrent group may be attributable to increased brain resilience, contrary to the transient temporal effect observed in subjects who experienced a depressive episode.

  2. Space Shuttle Glider. Educational Brief.

    Science.gov (United States)

    National Aeronautics and Space Administration, Washington, DC.

    Space Shuttle Glider is a scale model of the U.S. Space Shuttle orbiter. The airplane-like orbiter usually remains in Earth orbit for up to two weeks at a time. It normally carries a six- to seven-person crew which includes the mission commander, pilot, and several mission and/or payload specialists who have specialized training associated with…

  3. Proton scaling

    Energy Technology Data Exchange (ETDEWEB)

    Canavan, Gregory H [Los Alamos National Laboratory

    2009-01-01

    This note presents analytic estimates of the performance of proton beams in remote surveillance for nuclear materials. The analysis partitions the analysis into the eight steps used by a companion note: (1) Air scattering, (2) Neutron production in the ship and cargo, (3) Target detection probability, (4) Signal produced by target, (5) Attenuation of signal by ship and cargo, (6) Attenuation of signal by air, (7) Geometric dilution, and (8) Detector Efficiency. The above analyses indicate that the dominant air scattering and loss mechanisms for particle remote sensing are calculable with reliable and accepted tools. They make it clear that the conversion of proton beams into neutron sources rapidly goes to completion in all but thinnest targets, which means that proton interrogation is for all purposes executed by neutrons. Diffusion models and limiting approximations to them are simple and credible - apart from uncertainty over the cross sections to be used in them - and uncertainty over the structure of the vessels investigated. Multiplication is essentially unknown, in part because it depends on the details of the target and its shielding, which are unlikely to be known in advance. Attenuation of neutron fluxes on the way out are more complicated due to geometry, the spectrum of fission neutrons, and the details of their slowing down during egress. The attenuation by air is large but less uncertain. Detectors and technology are better known. The overall convolution of these effects lead to large but arguably tolerable levels of attenuation of input beams and output signals. That is particularly the case for small, mobile sensors, which can more than compensate for size with proximity to operate reliably while remaining below flux limits. Overall, the estimates used here appear to be of adequate accuracy for decisions. That assessment is strengthened by their agreement with companion calculations.

  4. Shuttle electrical environment

    Science.gov (United States)

    Smiddy, M.; Sullivan, W. P.; Girouard, D.; Anderson, P. B.

    1985-01-01

    Part of an AFGL payload flown on the STS-4 mission consisted of experiments to measure in-situ electric fields, electron densities, and vehicle charging. During this flight some 11 hours of data were acquired ranging from 5 minute snapshots up to continuous half-orbits. These experiments are described and results presented for such vehicle induced events as a main engine burn, thruster firings and water dumps in addition to undisturbed periods. The main characteristic of all the vehicle induced events is shown to be an enhancement in the low frequency noise (less than 2 kHz), in both the electrostatic and electron irregularity (delta N/N) spectra. The non-event results indicate that the electrostatic broadband emissions show a white noise characteristic in the low frequency range up to 2 kHz at an amplitude of 10 db above the shuttle design specification limit, falling below that limit above 10 kHz. The vehicle potential remained within the range of -3 to +1 volt throughout the flight which exhibits normal behavior for a satellite in a low equatorial orbit.

  5. Observation of the exhaust plume from the space shuttle main engines using the microwave limb sounder

    Directory of Open Access Journals (Sweden)

    H. C. Pumphrey

    2011-01-01

    Full Text Available A space shuttle launch deposits 700 tonnes of water in the atmosphere. Some of this water is released into the upper mesosphere and lower thermosphere where it may be directly detected by a limb sounding satellite instrument. We report measurements of water vapour plumes from shuttle launches made by the Microwave Limb Sounder (MLS on the Aura satellite. Approximately 50%–65% of shuttle launches are detected by MLS. The signal appears at a similar level across the upper 10 km of the MLS limb scan, suggesting that the bulk of the observed water is above the top of the scan. Only a small fraction at best of smaller launches (Ariane 5, Proton are detected. We conclude that the sensitivity of MLS is only just great enough to detect a shuttle sized launch, but that a suitably designed instrument of the same general type could detect the exhausts from a large proportion of heavy-lift launches.

  6. Physics Results From Alpha Magnetic Spectrometer 1998 Shuttle Flight

    CERN Document Server

    Huang, Ming-Huey A.

    2001-01-01

    The Alpha Magnetic Spectrometer (AMS) is a particle detector designed to detect antimatter. During the 10-day test flight on the space shuttle in June 1998, AMS detected $10^8$ events. Upon analysis, no antimatter was found and the antimatter limit was reduced to $1.1\\times10^{-6}$. The proton spectrum shows some differences with the cosmic ray flux used in atmospheric neutrino simulation. A large amount of protons, positrons, and electrons were found below the geomagnetic rigidity cutoff. The energy of these particles are as high as several GeV, one order of magnitude higher than any previously measured energy in radiation belts. These particles also exhibit many interesting features. This paper reviews the results in the four published papers of the AMS collaboration and provides explanation for some features of the albedo particles.

  7. Proton movies

    CERN Multimedia

    2009-01-01

    A humorous short film made by three secondary school students received an award at a Geneva film festival. Even without millions of dollars or Hollywood stars at your disposal, it is still possible to make a good science fiction film about CERN. That is what three students from the Collège Madame de Staël in Carouge, near Geneva, demonstrated. For their amateur short film on the LHC, they were commended by the jury of the video and multimedia festival for schools organised by the "Media in education" service of the Canton of Geneva’s Public Education Department. The film is a spoof of a television news report on the LHC start-up. In sequences full of humour and imagination, the reporter conducts interviews with a very serious "Professor Sairne", some protons preparing for their voyage and even the neutrons that were rejected by the LHC. "We got the idea of making a film about CERN at the end of the summer," explains Lucinda Päsche, one of the three students. "We did o...

  8. Anomalous Surface Diffusion of Protons on Lipid Membranes

    Science.gov (United States)

    Wolf, Maarten G.; Grubmüller, Helmut; Groenhof, Gerrit

    2014-01-01

    The cellular energy machinery depends on the presence and properties of protons at or in the vicinity of lipid membranes. To asses the energetics and mobility of a proton near a membrane, we simulated an excess proton near a solvated DMPC bilayer at 323 K, using a recently developed method to include the Grotthuss proton shuttling mechanism in classical molecular dynamics simulations. We obtained a proton surface affinity of −13.0 ± 0.5 kJ mol−1. The proton interacted strongly with both lipid headgroup and linker carbonyl oxygens. Furthermore, the surface diffusion of the proton was anomalous, with a subdiffusive regime over the first few nanoseconds, followed by a superdiffusive regime. The time- and distance dependence of the proton surface diffusion coefficient within these regimes may also resolve discrepancies between previously reported diffusion coefficients. Our simulations show that the proton anomalous surface diffusion originates from restricted diffusion in two different surface-bound states, interrupted by the occasional bulk-mediated long-range surface diffusion. Although only a DMPC membrane was considered in this work, we speculate that the restrictive character of the on-surface diffusion is highly sensitive to the specific membrane conditions, which can alter the relative contributions of the surface and bulk pathways to the overall diffusion process. Finally, we discuss the implications of our findings for the energy machinery. PMID:24988343

  9. Changes to the shuttle circuits

    CERN Multimedia

    GS Department

    2011-01-01

    To fit with passengers expectation, there will be some changes to the shuttle circuits as from Monday 10 October. See details on http://cern.ch/ShuttleService (on line on 7 October). Circuit No. 5 is cancelled as circuit No. 1 also stops at Bldg. 33. In order to guarantee shorter travel times, circuit No. 1 will circulate on Meyrin site only and circuit No. 2, with departures from Bldg. 33 and 500, on Prévessin site only. Site Services Section

  10. Proton-air and proton-proton cross sections

    Directory of Open Access Journals (Sweden)

    Ulrich Ralf

    2013-06-01

    Full Text Available Different attempts to measure hadronic cross sections with cosmic ray data are reviewed. The major results are compared to each other and the differences in the corresponding analyses are discussed. Besides some important differences, it is crucial to see that all analyses are based on the same fundamental relation of longitudinal air shower development to the observed fluctuation of experimental observables. Furthermore, the relation of the measured proton-air to the more fundamental proton-proton cross section is discussed. The current global picture combines hadronic proton-proton cross section data from accelerator and cosmic ray measurements and indicates a good consistency with predictions of models up to the highest energies.

  11. Properties and applications of perovskite proton conductors

    Directory of Open Access Journals (Sweden)

    Eduardo Caetano Camilo de Souza

    2010-09-01

    Full Text Available A brief overview is given of the main types and principles of solid-state proton conductors with perovskite structure. Their properties are summarized in terms of the defect chemistry, proton transport and chemical stability. A good understanding of these subjects allows the manufacturing of compounds with the desired electrical properties, for application in renewable and sustainable energy devices. A few trends and highlights of the scientific advances are given for some classes of protonic conductors. Recent results and future prospect about these compounds are also evaluated. The high proton conductivity of barium cerate and zirconate based electrolytes lately reported in the literature has taken these compounds to a highlight position among the most studied conductor ceramic materials.

  12. Data acquisition system for a proton imaging apparatus

    CERN Document Server

    Sipala, V; Bruzzi, M; Bucciolini, M; Candiano, G; Capineri, L; Cirrone, G A P; Civinini, C; Cuttone, G; Lo Presti, D; Marrazzo, L; Mazzaglia, E; Menichelli, D; Randazzo, N; Talamonti, C; Tesi, M; Valentini, S

    2009-01-01

    New developments in the proton-therapy field for cancer treatments, leaded Italian physics researchers to realize a proton imaging apparatus consisting of a silicon microstrip tracker to reconstruct the proton trajectories and a calorimeter to measure their residual energy. For clinical requirements, the detectors used and the data acquisition system should be able to sustain about 1 MHz proton rate. The tracker read-out, using an ASICs developed by the collaboration, acquires the signals detector and sends data in parallel to an FPGA. The YAG:Ce calorimeter generates also the global trigger. The data acquisition system and the results obtained in the calibration phase are presented and discussed.

  13. Proton pump inhibitors

    Science.gov (United States)

    Proton pump inhibitors (PPIs) are medicines that work by reducing the amount of stomach acid made by glands in ... Proton pump inhibitors are used to: Relieve symptoms of acid reflux, or gastroesophageal reflux disease (GERD). This is a ...

  14. Proton: The Particle

    Energy Technology Data Exchange (ETDEWEB)

    Suit, Herman

    2013-11-01

    The purpose of this article is to review briefly the nature of protons: creation at the Big Bang, abundance, physical characteristics, internal components, and life span. Several particle discoveries by proton as the experimental tool are considered. Protons play important roles in science, medicine, and industry. This article was prompted by my experience in the curative treatment of cancer patients by protons and my interest in the nature of protons as particles. The latter has been stimulated by many discussions with particle physicists and reading related books and journals. Protons in our universe number ≈10{sup 80}. Protons were created at 10{sup −6} –1 second after the Big Bang at ≈1.37 × 10{sup 10} years beforethe present. Proton life span has been experimentally determined to be ≥10{sup 34} years; that is, the age of the universe is 10{sup −24}th of the minimum life span of a proton. The abundance of the elements is hydrogen, ≈74%; helium, ≈24%; and heavier atoms, ≈2%. Accordingly, protons are the dominant baryonic subatomic particle in the universe because ≈87% are protons. They are in each atom in our universe and thus involved in virtually every activity of matter in the visible universe, including life on our planet. Protons were discovered in 1919. In 1968, they were determined to be composed of even smaller particles, principally quarks and gluons. Protons have been the experimental tool in the discoveries of quarks (charm, bottom, and top), bosons (W{sup +}, W{sup −}, Z{sup 0}, and Higgs), antiprotons, and antineutrons. Industrial applications of protons are numerous and important. Additionally, protons are well appreciated in medicine for their role in radiation oncology and in magnetic resonance imaging. Protons are the dominant baryonic subatomic particle in the visible universe, comprising ≈87% of the particle mass. They are present in each atom of our universe and thus a participant in every activity involving matter.

  15. Proton: the particle.

    Science.gov (United States)

    Suit, Herman

    2013-11-01

    The purpose of this article is to review briefly the nature of protons: creation at the Big Bang, abundance, physical characteristics, internal components, and life span. Several particle discoveries by proton as the experimental tool are considered. Protons play important roles in science, medicine, and industry. This article was prompted by my experience in the curative treatment of cancer patients by protons and my interest in the nature of protons as particles. The latter has been stimulated by many discussions with particle physicists and reading related books and journals. Protons in our universe number ≈10(80). Protons were created at 10(-6) -1 second after the Big Bang at ≈1.37 × 10(10) years beforethe present. Proton life span has been experimentally determined to be ≥10(34) years; that is, the age of the universe is 10(-24)th of the minimum life span of a proton. The abundance of the elements is hydrogen, ≈74%; helium, ≈24%; and heavier atoms, ≈2%. Accordingly, protons are the dominant baryonic subatomic particle in the universe because ≈87% are protons. They are in each atom in our universe and thus involved in virtually every activity of matter in the visible universe, including life on our planet. Protons were discovered in 1919. In 1968, they were determined to be composed of even smaller particles, principally quarks and gluons. Protons have been the experimental tool in the discoveries of quarks (charm, bottom, and top), bosons (W(+), W(-), Z(0), and Higgs), antiprotons, and antineutrons. Industrial applications of protons are numerous and important. Additionally, protons are well appreciated in medicine for their role in radiation oncology and in magnetic resonance imaging. Protons are the dominant baryonic subatomic particle in the visible universe, comprising ≈87% of the particle mass. They are present in each atom of our universe and thus a participant in every activity involving matter. Copyright © 2013 Elsevier Inc. All

  16. Digital coding of Shuttle TV

    Science.gov (United States)

    Habibi, A.; Batson, B.

    1976-01-01

    Space Shuttle will be using a field-sequential color television system for the first few missions, but the present plans are to switch to a NTSC color TV system for future missions. The field-sequential color TV system uses a modified black and white camera, producing a TV signal with a digital bandwidth of about 60 Mbps. This article discusses the characteristics of the Shuttle TV systems and proposes a bandwidth-compression technique for the field-sequential color TV system that could operate at 13 Mbps to produce a high-fidelity signal. The proposed bandwidth-compression technique is based on a two-dimensional DPCM system that utilizes temporal, spectral, and spatial correlation inherent in the field-sequential color TV imagery. The proposed system requires about 60 watts and less than 200 integrated circuits.

  17. Space Shuttle Corrosion Protection Performance

    Science.gov (United States)

    Curtis, Cris E.

    2007-01-01

    The reusable Manned Space Shuttle has been flying into Space and returning to earth for more than 25 years. The launch pad environment can be corrosive to metallic substrates and the Space Shuttles are exposed to this environment when preparing for launch. The Orbiter has been in service well past its design life of 10 years or 100 missions. As part of the aging vehicle assessment one question under evaluation is how the thermal protection system and aging protective coatings are performing to insure structural integrity. The assessment of this cost resources and time. The information is invaluable when minimizing risk to the safety of Astronauts and Vehicle. This paper will outline a strategic sampling plan and some operational improvements made by the Orbiter Structures team and Corrosion Control Review Board.

  18. Nucleocytoplasmic shuttling of transcription factors

    DEFF Research Database (Denmark)

    Cartwright, P; Helin, K

    2000-01-01

    To elicit the transcriptional response following intra- or extracellular stimuli, the signals need to be transmitted to their site of action within the nucleus. The nucleocytoplasmic shuttling of transcription factors is a mechanism mediating this process. The activation and inactivation of the t......To elicit the transcriptional response following intra- or extracellular stimuli, the signals need to be transmitted to their site of action within the nucleus. The nucleocytoplasmic shuttling of transcription factors is a mechanism mediating this process. The activation and inactivation...... transcription factor families are regulated by similar mechanisms, there are several differences that allow for the specific activation of each transcription factor. This review discusses the general import and export pathways found to be common amongst many different transcription factors, and highlights...... a select group of transcription factors that demonstrate the diversity displayed in their mode of activation and inactivation....

  19. Shuttle Radar Topography Mission (SRTM)

    Science.gov (United States)

    ,

    2009-01-01

    Under an agreement with the National Aeronautics and Space Administration (NASA) and the Department of Defense's National Geospatial-Intelligence Agency (NGA), the U.S. Geological Survey (USGS) is distributing elevation data from the Shuttle Radar Topography Mission (SRTM). The SRTM is a joint project of NASA and NGA to map the Earth's land surface in three dimensions at an unprecedented level of detail. As part of space shuttle Endeavour's flight during February 11-22, 2000, the SRTM successfully collected data over 80 percent of the Earth's land surface for most of the area between latitudes 60 degrees north and 56 degrees south. The SRTM hardware included the Spaceborne Imaging Radar-C (SIR-C) and X-band Synthetic Aperture Radar (X-SAR) systems that had flown twice previously on other space shuttle missions. The SRTM data were collected with a technique known as interferometry that allows image data from dual radar antennas to be processed for the extraction of ground heights.

  20. Space Shuttle Star Tracker Challenges

    Science.gov (United States)

    Herrera, Linda M.

    2010-01-01

    The space shuttle fleet of avionics was originally designed in the 1970's. Many of the subsystems have been upgraded and replaced, however some original hardware continues to fly. Not only fly, but has proven to be the best design available to perform its designated task. The shuttle star tracker system is currently flying as a mixture of old and new designs, each with a unique purpose to fill for the mission. Orbiter missions have tackled many varied missions in space over the years. As the orbiters began flying to the International Space Station (ISS), new challenges were discovered and overcome as new trusses and modules were added. For the star tracker subsystem, the growing ISS posed an unusual problem, bright light. With two star trackers on board, the 1970's vintage image dissector tube (IDT) star trackers track the ISS, while the new solid state design is used for dim star tracking. This presentation focuses on the challenges and solutions used to ensure star trackers can complete the shuttle missions successfully. Topics include KSC team and industry partner methods used to correct pressurized case failures and track system performance.

  1. Proton therapy physics

    CERN Document Server

    2012-01-01

    Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also exami...

  2. PREFACE: Transport phenomena in proton conducting media Transport phenomena in proton conducting media

    Science.gov (United States)

    Eikerling, Michael

    2011-06-01

    Proton transport phenomena are of paramount importance for acid-base chemistry, energy transduction in biological organisms, corrosion processes, and energy conversion in electrochemical systems such as polymer electrolyte fuel cells. The relevance for such a plethora of materials and systems, and the ever-lasting fascination with the highly concerted nature of underlying processes drive research across disciplines in chemistry, biology, physics and chemical engineering. A proton never travels alone. Proton motion is strongly correlated with its environment, usually comprised of an electrolyte and a solid or soft host material. For the transport in nature's most benign proton solvent and shuttle, water that is, insights from ab initio simulations, matured over the last 15 years, have furnished molecular details of the structural diffusion mechanism of protons. Excess proton movement in water consists of sequences of Eigen-Zundel-Eigen transitions, triggered by hydrogen bond breaking and making in the surrounding water network. Nowadays, there is little debate about the validity of this mechanism in water, which bears a stunning resemblance to the basic mechanistic picture put forward by de Grotthuss in 1806. While strong coupling of an excess proton with degrees of freedom of solvent and host materials facilitates proton motion, this coupling also creates negative synergies. In general, proton mobility in biomaterials and electrochemical proton conducting media is highly sensitive to the abundance and structure of the proton solvent. In polymer electrolyte membranes, in which protons are bound to move in nano-sized water-channels, evaporation of water or local membrane dehydration due to electro-osmotic coupling are well-known phenomena that could dramatically diminish proton conductivity. Contributions in this special issue address various vital aspects of the concerted nature of proton motion and they elucidate important structural and dynamic effects of solvent

  3. Space Shuttle and Hypersonic Entry

    Science.gov (United States)

    Campbell, Charles H.; Gerstenmaier, William H.

    2014-01-01

    Fifty years of human spaceflight have been characterized by the aerospace operations of the Soyuz, of the Space Shuttle and, more recently, of the Shenzhou. The lessons learned of this past half decade are important and very significant. Particularly interesting is the scenario that is downstream from the retiring of the Space Shuttle. A number of initiatives are, in fact, emerging from in the aftermath of the decision to terminate the Shuttle program. What is more and more evident is that a new era is approaching: the era of the commercial usage and of the commercial exploitation of space. It is probably fair to say, that this is the likely one of the new frontiers of expansion of the world economy. To make a comparison, in the last 30 years our economies have been characterized by the digital technologies, with examples ranging from computers, to cellular phones, to the satellites themselves. Similarly, the next 30 years are likely to be characterized by an exponential increase of usage of extra atmospheric resources, as a result of more economic and efficient way to access space, with aerospace transportation becoming accessible to commercial investments. We are witnessing the first steps of the transportation of future generation that will drastically decrease travel time on our Planet, and significantly enlarge travel envelope including at least the low Earth orbits. The Steve Jobs or the Bill Gates of the past few decades are being replaced by the aggressive and enthusiastic energy of new entrepreneurs. It is also interesting to note that we are now focusing on the aerospace band, that lies on top of the aeronautical shell, and below the low Earth orbits. It would be a mistake to consider this as a known envelope based on the evidences of the flights of Soyuz, Shuttle and Shenzhou. Actually, our comprehension of the possible hypersonic flight regimes is bounded within really limited envelopes. The achievement of a full understanding of the hypersonic flight

  4. Proton-Proton and Proton-Antiproton Colliders

    CERN Document Server

    Scandale, Walter

    2014-01-01

    In the last five decades, proton–proton and proton–antiproton colliders have been the most powerful tools for high energy physics investigations. They have also deeply catalyzed innovation in accelerator physics and technology. Among the large number of proposed colliders, only four have really succeeded in becoming operational: the ISR, the SppbarS, the Tevatron and the LHC. Another hadron collider, RHIC, originally conceived for ion–ion collisions, has also been operated part-time with polarized protons. Although a vast literature documenting them is available, this paper is intended to provide a quick synthesis of their main features and key performance.

  5. Death of the TonB shuttle hypothesis

    Directory of Open Access Journals (Sweden)

    Michael George Gresock

    2011-10-01

    Full Text Available A complex of ExbB, ExbD, and TonB transduces cytoplasmic membrane (CM proton motive force (pmf to outer membrane (OM transporters so that large, scarce, and important nutrients can be released into the periplasmic space for subsequent transport across the CM. TonB is the component that interacts with the OM transporters and enables ligand transport, and several mechanical models and a shuttle model explain how TonB might work. In the mechanical models, TonB remains attached to the CM during energy transduction, while in the shuttle model the TonB N terminus leaves the CM to deliver conformationally stored potential energy to OM transporters. Previous efforts to test the shuttle model by anchoring TonB to the CM by fusion to a large globular cytoplasmic protein have been hampered by the proteolytic susceptibility of the fusion constructs. Here we confirm that GFP-TonB, tested in a previous study by another laboratory, again gave rise to full-length TonB and slightly larger potentially shuttleable fragments that prevented unambiguous interpretation of the data. Recently, we discovered that a fusion of the Vibrio cholerae ToxR cytoplasmic domain to the N terminus of TonB was proteolytically stable. ToxR-TonB was able to be completely converted into a proteinase K-resistant conformation in response to loss of pmf in spheroplasts and exhibited an ability to form a pmf-dependent formaldehyde crosslink to ExbD, both indicators of its location in the CM. Most importantly, ToxR-TonB had the same relative specific activity as wild-type TonB. Taken together, these results provide the first conclusive evidence that TonB does not shuttle during energy transduction. The interpretations of our previous study, which concluded that TonB shuttled in vivo, were complicated by the fact that the probe used in those studies, Oregon Green® 488 maleimide, was permeant to the CM and could label proteins, including a TonB ∆TMD derivative, confined exclusively to the

  6. Anisotropic amplification of proton transport in proton exchange membrane fuel cells

    Science.gov (United States)

    Thimmappa, Ravikumar; Fawaz, Mohammed; Devendrachari, Mruthyunjayachari Chattanahalli; Gautam, Manu; Kottaichamy, Alagar Raja; Shafi, Shahid Pottachola; Thotiyl, Musthafa Ottakam

    2017-07-01

    Though graphene oxide (GO) membrane shuttles protons under humid conditions, it suffer severe disintegration and anhydrous conditions lead to abysmal ionic conductivity. The trade-off between mechanical integrity and ionic conductivity challenge the amplification of GO's ionic transport under anhydrous conditions. We show anisotropic amplification of GO's ionic transport with a selective amplification of in plane contribution under anhydrous conditions by doping it with a plant extract, phytic acid (PA). The hygroscopic nature of PA stabilized interlayer water molecules and peculiar geometry of sbnd OH functionalities around saturated hydrocarbon ring anisotropically enhanced ionic transport amplifying the fuel cell performance metrics.

  7. Electromagnetic Compatibility for the Space Shuttle

    Science.gov (United States)

    Scully, Robert C.

    2004-01-01

    This slide presentation reviews the Space Shuttle electromagnetic compatibility (EMC). It includes an overview of the design of the shuttle with the areas that are of concern for the electromagnetic compatibility. It includes discussion of classical electromagnetic interference (EMI) and the work performed to control the electromagnetic interference. Another area of interest is electrostatic charging and the threat of electrostatic discharge and the attempts to reduce damage to the Shuttle from these possible hazards. The issue of electrical bonding is als reviewed. Lastly the presentation reviews the work performed to protect the shuttle from lightning, both in flight and on the ground.

  8. Shot noise of a quantum shuttle

    DEFF Research Database (Denmark)

    Novotny, Tomas; Donarini, Andrea; Flindt, Christian

    2004-01-01

    We formulate a theory for shot noise in quantum nanoelectromechanical systems. As a specific example, the theory is applied to a quantum shuttle, and the zero-frequency noise, measured by the Fano factor F, is computed. F reaches very low values (Fsimilar or equal to10(-2)) in the shuttling regime...... even in the quantum limit, confirming that shuttling is universally a low noise phenomenon. In approaching the semiclassical limit, the Fano factor shows a giant enhancement (Fsimilar or equal to10(2)) at the shuttling threshold, consistent with predictions based on phase-space representations...

  9. Protons in Jupiter's Magnetosphere

    Science.gov (United States)

    Bodisch, K. M.; Bagenal, F.; Dougherty, L.

    2016-12-01

    The solar wind, the icy moons and Jupiter's ionosphere are all potential sources of protons found in the Jovian magnetosphere. In an attempt to quantify the relative importance of these different sources we explore the spatial distribution of density and temperature of the protons in Jupiter's magnetosphere. Through re-analysis of Voyager 1 and 2 Plasma Science (PLS) data obtained between 4 and 40 RJ we produce temperature and density profiles of protons in those regions. By combining profiles of protons and heavy ions (under the assumption of anisotropic Maxwellian distributions) we extrapolate the ion densities along the magnetic field to create global maps of proton density and temperature. Using these models of plasma distributions in the Jovian magnetosphere we predict the proton conditions likely encountered by the Juno spacecraft along its trajectory.

  10. The proton radius puzzle

    Science.gov (United States)

    Paz, Gil

    2017-09-01

    In 2010 the proton charge radius was extracted for the first time from muonic hydrogen, a bound state of a muon and a proton. The value obtained was five standard deviations away from the regular hydrogen extraction. Taken at face value, this might be an indication of a new force in nature coupling to muons, but not to electrons. It also forces to reexamine our understanding of the structure of the proton. In this talk I will describe an ongoing theoretical research effort that seeks to address and resolve this ''proton radius puzzle''. In particular, I will present a reevaluation of the proton structure effects, correcting 40 years of such calculations, and the development of new effective field theoretical tools that would allow to directly connect muonic hydrogen and muon-proton scattering.

  11. Shuttle onboard IMU alignment methods

    Science.gov (United States)

    Henderson, D. M.

    1976-01-01

    The current approach to the shuttle IMU alignment is based solely on the Apollo Deterministic Method. This method is simple, fast, reliable and provides an accurate estimate for the present cluster to mean of 1,950 transformation matrix. If four or more star sightings are available, the application of least squares analysis can be utilized. The least squares method offers the next level of sophistication to the IMU alignment solution. The least squares method studied shows that a more accurate estimate for the misalignment angles is computed, and the IMU drift rates are a free by-product of the analysis. Core storage requirements are considerably more; estimated 20 to 30 times the core required for the Apollo Deterministic Method. The least squares method offers an intermediate solution utilizing as much data that is available without a complete statistical analysis as in Kalman filtering.

  12. Shuttle Spacelab Core Equipment Freezer

    Science.gov (United States)

    Copeland, R. J.

    1977-01-01

    This paper describes the preliminary design of a Shuttle Spacelab Core Equipment Freezer. The unit will provide the capability to freeze and store many experiment specimens. Two models of the unit are planned. One model provides storage at -70 C; the other model will provide -70 C storage, a freeze dry capability, storage at a selectable temperature in the range of 0 C to -70 C, and means of maintaining close temperature tolerances. In addition an exchanger loop will be available at 4 C for cooling of a centrifuge and a remote storage compartment. A test tube holder, a dish holder and thermal capacitors for rapid freezing of large specimens will also be provided. A Stirling Cycle was selected as the active refrigerator for minimum cost and weight.

  13. Space Shuttle Orbiter-Illustration

    Science.gov (United States)

    2001-01-01

    This illustration is an orbiter cutaway view with callouts. The orbiter is both the brains and heart of the Space Transportation System (STS). About the same size and weight as a DC-9 aircraft, the orbiter contains the pressurized crew compartment (which can normally carry up to seven crew members), the huge cargo bay, and the three main engines mounted on its aft end. There are three levels to the crew cabin. Uppermost is the flight deck where the commander and the pilot control the mission. The middeck is where the gallery, toilet, sleep stations, and storage and experiment lockers are found for the basic needs of weightless daily living. Also located in the middeck is the airlock hatch into the cargo bay and space beyond. It is through this hatch and airlock that astronauts go to don their spacesuits and marned maneuvering units in preparation for extravehicular activities, more popularly known as spacewalks. The Space Shuttle's cargo bay is adaptable to hundreds of tasks. Large enough to accommodate a tour bus (60 x 15 feet or 18.3 x 4.6 meters), the cargo bay carries satellites, spacecraft, and spacelab scientific laboratories to and from Earth orbit. It is also a work station for astronauts to repair satellites, a foundation from which to erect space structures, and a hold for retrieved satellites to be returned to Earth. Thermal tile insulation and blankets (also known as the thermal protection system or TPS) cover the underbelly, bottom of the wings, and other heat-bearing surfaces of the orbiter to protect it during its fiery reentry into the Earth's atmosphere. The Shuttle's 24,000 individual tiles are made primarily of pure-sand silicate fibers, mixed with a ceramic binder. The solid rocket boosters (SRB's) are designed as an in-house Marshall Space Flight Center project, with United Space Boosters as the assembly and refurbishment contractor. The solid rocket motor (SRM) is provided by the Morton Thiokol Corporation.

  14. The Shuttle Radar Topography Mission

    Science.gov (United States)

    Farr, T. G.; Kobrick, M.

    2001-12-01

    The Shuttle Radar Topography Mission (SRTM), which flew successfully aboard Endeavour in February 2000, is a cooperative project between NASA, the National Imagery and Mapping Agency, and the German and Italian Space Agencies. The mission was designed to use a single-pass radar interferometer to produce a digital elevation model of the Earth's land surface between about 60 degrees north and 56 degrees south latitude. The DEM will have 30 m horizontal resolution and better than 15 m vertical errors. Two ortho-rectified C-band image mosaics are also planned. Data processing will be completed by the end of 2002. SRTM used a modification of the radar instrument that comprised the Spaceborne Radar Laboratory that flew twice on the Shuttle Endeavour in 1994. To collect the interferometric data, a 60 m mast, additional C-band antenna, and improved tracking and navigation devices were added. A second X-band antenna was also added by the German Space Agency, and produced higher resolution topographic measurements in strips nested within the full, C-band coverage. First results indicate that the radars and ancillary instruments worked very well. Data played back to the ground during the flight were processed to DEMs and products released hours after acquisition. An extensive program for calibration and verification of the SRTM data is now underway. When complete later this year, systematic processing of the data will begin, with final products emerging a continent at a time. Products will be transferred to the US Geological Survey's EROS Data Center for civilian archive and distribution. NIMA will handle Department of Defense distribution. * Work performed under contract to NASA.

  15. Space Shuttle RTOS Bayesian Network

    Science.gov (United States)

    Morris, A. Terry; Beling, Peter A.

    2001-01-01

    With shrinking budgets and the requirements to increase reliability and operational life of the existing orbiter fleet, NASA has proposed various upgrades for the Space Shuttle that are consistent with national space policy. The cockpit avionics upgrade (CAU), a high priority item, has been selected as the next major upgrade. The primary functions of cockpit avionics include flight control, guidance and navigation, communication, and orbiter landing support. Secondary functions include the provision of operational services for non-avionics systems such as data handling for the payloads and caution and warning alerts to the crew. Recently, a process to selection the optimal commercial-off-the-shelf (COTS) real-time operating system (RTOS) for the CAU was conducted by United Space Alliance (USA) Corporation, which is a joint venture between Boeing and Lockheed Martin, the prime contractor for space shuttle operations. In order to independently assess the RTOS selection, NASA has used the Bayesian network-based scoring methodology described in this paper. Our two-stage methodology addresses the issue of RTOS acceptability by incorporating functional, performance and non-functional software measures related to reliability, interoperability, certifiability, efficiency, correctness, business, legal, product history, cost and life cycle. The first stage of the methodology involves obtaining scores for the various measures using a Bayesian network. The Bayesian network incorporates the causal relationships between the various and often competing measures of interest while also assisting the inherently complex decision analysis process with its ability to reason under uncertainty. The structure and selection of prior probabilities for the network is extracted from experts in the field of real-time operating systems. Scores for the various measures are computed using Bayesian probability. In the second stage, multi-criteria trade-off analyses are performed between the scores

  16. Liquid Hydrogen Consumption During Space Shuttle Program

    Science.gov (United States)

    Partridge, Jonathan K.

    2011-01-01

    This slide presentation reviews the issue of liquid hydrogen consumption and the points of its loss in prior to the shuttle launch. It traces the movement of the fuel from the purchase to the on-board quantity and the loss that results in 54.6 of the purchased quantity being on board the Shuttle.

  17. Shuttle Entry Imaging Using Infrared Thermography

    Science.gov (United States)

    Horvath, Thomas; Berry, Scott; Alter, Stephen; Blanchard, Robert; Schwartz, Richard; Ross, Martin; Tack, Steve

    2007-01-01

    During the Columbia Accident Investigation, imaging teams supporting debris shedding analysis were hampered by poor entry image quality and the general lack of information on optical signatures associated with a nominal Shuttle entry. After the accident, recommendations were made to NASA management to develop and maintain a state-of-the-art imagery database for Shuttle engineering performance assessments and to improve entry imaging capability to support anomaly and contingency analysis during a mission. As a result, the Space Shuttle Program sponsored an observation campaign to qualitatively characterize a nominal Shuttle entry over the widest possible Mach number range. The initial objectives focused on an assessment of capability to identify/resolve debris liberated from the Shuttle during entry, characterization of potential anomalous events associated with RCS jet firings and unusual phenomenon associated with the plasma trail. The aeroheating technical community viewed the Space Shuttle Program sponsored activity as an opportunity to influence the observation objectives and incrementally demonstrate key elements of a quantitative spatially resolved temperature measurement capability over a series of flights. One long-term desire of the Shuttle engineering community is to calibrate boundary layer transition prediction methodologies that are presently part of the Shuttle damage assessment process using flight data provided by a controlled Shuttle flight experiment. Quantitative global imaging may offer a complementary method of data collection to more traditional methods such as surface thermocouples. This paper reviews the process used by the engineering community to influence data collection methods and analysis of global infrared images of the Shuttle obtained during hypersonic entry. Emphasis is placed upon airborne imaging assets sponsored by the Shuttle program during Return to Flight. Visual and IR entry imagery were obtained with available airborne

  18. Giving Protons a Boost

    CERN Multimedia

    2004-01-01

    The first of LHC's superconducting radio-frequency cavity modules has passed its final test at full power in the test area of building SM18. These modules carry an oscillating electric field that will accelerate protons around the LHC ring and help maintain the stability of the proton beams.

  19. Current Noise Spectrum of a Quantum Shuttle

    DEFF Research Database (Denmark)

    Flindt, Christian; Novotny, T.; Jauho, Antti-Pekka

    2005-01-01

    peaks at integer multiples of the mechanical frequency, which is slightly renormalized. The renormalization explains a previously observed small deviation of the shuttle Current compared to the expected value given by the product of the natural mechanical frequency and the electron charge. For a certain......We present a method for calculating the full current noise spectrum S(omega) for the class of nano-electromechanical systems (NEMS) that can be described by a Markovian generalized master equation. As a specific example we apply the method to a quantum shuttle. The noise spectrum of the shuttle has...... parameter range the quantum shuttle exhibits a coexistence regime, where the charges are transported by two different mechanisms: Shuttling and sequential tunneling. In our previous studies we showed that characteristic features in the zero-frequency noise could be quantitatively understood as a slow...

  20. Chemical Shuttle Additives in Lithium Ion Batteries

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, Mary

    2013-03-31

    The goals of this program were to discover and implement a redox shuttle that is compatible with large format lithium ion cells utilizing LiNi{sub 1/3}Mn{sub 1/3}Co{sub 1/3}O{sub 2} (NMC) cathode material and to understand the mechanism of redox shuttle action. Many redox shuttles, both commercially available and experimental, were tested and much fundamental information regarding the mechanism of redox shuttle action was discovered. In particular, studies surrounding the mechanism of the reduction of the oxidized redox shuttle at the carbon anode surface were particularly revealing. The initial redox shuttle candidate, namely 2-(pentafluorophenyl)-tetrafluoro-1,3,2-benzodioxaborole (BDB) supplied by Argonne National Laboratory (ANL, Lemont, Illinois), did not effectively protect cells containing NMC cathodes from overcharge. The ANL-RS2 redox shuttle molecule, namely 1,4-bis(2-methoxyethoxy)-2,5-di-tert-butyl-benzene, which is a derivative of the commercially successful redox shuttle 2,5-di-tert-butyl-1,4-dimethoxybenzene (DDB, 3M, St. Paul, Minnesota), is an effective redox shuttle for cells employing LiFePO{sub 4} (LFP) cathode material. The main advantage of ANL-RS2 over DDB is its larger solubility in electrolyte; however, ANL-RS2 is not as stable as DDB. This shuttle also may be effectively used to rebalance cells in strings that utilize LFP cathodes. The shuttle is compatible with both LTO and graphite anode materials although the cell with graphite degrades faster than the cell with LTO, possibly because of a reaction with the SEI layer. The degradation products of redox shuttle ANL-RS2 were positively identified. Commercially available redox shuttles Li{sub 2}B{sub 12}F{sub 12} (Air Products, Allentown, Pennsylvania and Showa Denko, Japan) and DDB were evaluated and were found to be stable and effective redox shuttles at low C-rates. The Li{sub 2}B{sub 12}F{sub 12} is suitable for lithium ion cells utilizing a high voltage cathode (potential that is higher

  1. Sustainable Food & Sustainable Economics

    OpenAIRE

    Alvarez, Mavis Dora

    2012-01-01

    Cuba today is immersed in a very intense process of perfecting its agricultural production structures with the goal of making them more efficient and sustainable in their economic administration and in their social and environmental management. Agricultural cooperatives in Cuba have the responsibility of producing on 73% of the country's farmland. Their contributions are decisive to developing agricultural production and to ensuring more and better food for the population, in addition to redu...

  2. Proton-Proton Physics with ALICE

    CERN Document Server

    Grosse-Oetringhaus, J F

    2008-01-01

    The goal of the ALICE experiment at LHC is to study strongly interacting matter at high energy densities as well as the signatures and properties of the quark-gluon plasma. This goal manifests itself in a rich physics program. Although ALICE will mainly study heavy-ion collisions, a dedicated program will concentrate on proton-proton physics. The first part will introduce the ALICE experiment from a pp measurement's point of view. Two unique properties are its low pT cut-off and the excellent PID capabilities. The various topics of the proton-proton physics program, which will allow a close scrutiny of existing theoretical models, will be described. Furthermore, the interpretation of measurements of heavy-ion collisions necessitates the comparison to measurements of pp collisions. The second part will concentrate on the day-1 physics program of ALICE. At startup, neither the LHC luminosity nor its energy will have their nominal values. Furthermore, the ALICE detector is in the process of being aligned and cal...

  3. Advantages of a round-body shuttle

    Science.gov (United States)

    Arrington, James P.; Wells, William L.; Lepsch, Roger A., Jr.; Huffman, Jarrett K.; Macconochie, Ian O.

    1989-01-01

    A cylindrical fuselage cross-section SSTOV representing the design generation beyond the current NASA Space Shuttle has been projected capable of reducing the cost of payload delivery to orbit while increasing mission scope. Due to its intrinsically greater wetted-area and structural weight efficiencies, this cylindrical vehicle would carry 40 percent greater payload than the Space Shuttle system despite a 20-percent lower gross liftoff weight. A LOX/hydrocarbon fuel combination would be employed during the early portion of flight, thereupon shifting to LOX/hydrogen. The cylindrical SSTOV would have eight times the volume of the Space Shuttle Orbiter.

  4. Lorentz contracted proton

    Energy Technology Data Exchange (ETDEWEB)

    Fierro, D. Bedoya; Kelkar, N.G.; Nowakowski, M. [Dept. de Fisica, Universidad de los Andes, Cra. 1E No. 18A-10, Santafe de Bogota (Colombia)

    2015-09-30

    The proton charge and magnetization density distributions can be related to the well known Sachs electromagnetic form factors G{sub E,M}(/emph {q}{sup 2}) through Fourier transforms, only in the Breit frame. The Breit frame however moves with relativistic velocities in the Lab and a Lorentz boost must be applied before extracting the static properties of the proton from the corresponding densities. Apart from this, the Fourier transform relating the densities and form factors is inherently a non-relativistic expression. We show that the relativistic corrections to it can be obtained by extending the standard Breit equation to higher orders in its 1/c{sup 2} expansion. We find that the inclusion of the above corrections reduces the size of the proton as determined from electron proton scattering data by about 4%.

  5. Inauguration of Proton Synchrotron

    CERN Multimedia

    1960-01-01

    On 5 February 1960, the Proton Synchrotron (PS) was formally inaugurated. The great Danish physicist, Niels Bohr, releases a bottle of champagne against a shielding block to launch the PS on its voyage in physics.

  6. Proton computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, K.M.

    1978-01-01

    The use of protons or other heavy charged particles instead of x rays in computed tomography (CT) is explored. The results of an experimental implementation of proton CT are presented. High quality CT reconstructions are obtained at an average dose reduction factor compared with an EMI 5005 x-ray scanner of 10:1 for a 30-cm-diameter phantom and 3.5:1 for a 20-cm diameter. The spatial resolution is limited by multiple Coulomb scattering to about 3.7 mm FWHM. Further studies are planned in which proton and x-ray images of fresh human specimens will be compared. Design considerations indicate that a clinically useful proton CT scanner is eminently feasible.

  7. Plant proton pumps

    DEFF Research Database (Denmark)

    Gaxiola, Roberto A.; Palmgren, Michael Gjedde; Schumacher, Karin

    2007-01-01

    Chemiosmotic circuits of plant cells are driven by proton (H+) gradients that mediate secondary active transport of compounds across plasma and endosomal membranes. Furthermore, regulation of endosomal acidification is critical for endocytic and secretory pathways. For plants to react...

  8. Jovian proton aurora

    Science.gov (United States)

    Heaps, M. G.; Edgar, B. C.; Green, A. E. S.

    1975-01-01

    Auroral and polar cap emissions in a model Jovian atmosphere are determined for proton precipitation. The incident protons, which are characterized by representative spectra, are degraded in energy by applying the continuous slowing down approximation. All secondary and higher generation electrons are assumed to be absorbed locally and their contributions to the total emissions are included. Volume emission rates are calculated from the total direct excitation rates with corrections for cascading applied. Results show that most molecular hydrogen and helium emissions for polar cap precipitation are below the ambient dayglow values. Charge capture by precipitating protons is an important source of Lyman alpha and Balmer alpha emissions and offers a key to the detection of large fluxes of low energy protons.

  9. Proton conduction in phosphatidylethanolamine.

    Science.gov (United States)

    Murase, N; Gonda, K; Kagami, I; Koga, S

    1977-08-01

    The dc conductivity of polycrystalline phosphatidylethanolamine (PE) was measured in the temperature range 60-120 degrees C. Since no conclusive evidence had so far been obtained for the presence of proteon conduction in this phospholipid, hydrogen gas was shown in the present experiment to evolve during the electrolysis in its premelted state between 91 and 124 degrees C. In this temperature range molecules assume rotation around the molecular axes and proton conduction of the Grotthus type takes place possibly along two chains of intermolecular hydrogen bonds running in parallel. Zwitter-ions behave cooperatively as proton donors and acceptors in transferring proton from molecule and molecule via the hydrogen bond networks. This efficient push-pull way of proton transferring seems to account for the fact that no polarization was observed in the dc conduction experiments. The amount of devolved gas appears to be not exactly in accordance with Faraday's law and discussions are made on possible causes for this slight deviation.

  10. The Proton Radius Puzzle

    Directory of Open Access Journals (Sweden)

    Downie E. J.

    2016-01-01

    Full Text Available The proton radius puzzle is the difference between the proton radius as measured with electron scattering and in the excitation spectrum of atomic hydrogen, and that measured with muonic hydrogen spectroscopy. Since the inception of the proton radius puzzle in 2010 by the measurement of Pohl et al.[1], many possible resolutions to the puzzle have been postulated, but, to date, none has been generally accepted. New data are therefore necessary to resolve the issue. We briefly review the puzzle, the proposed solutions, and the new electron scattering and spectroscopy experiments planned and underway. We then introduce the MUSE experiment, which seeks to resolve the puzzle by simultaneously measuring elastic electron and muon scattering on the proton, in both charge states, thereby providing new information to the puzzle. MUSE addresses issues of two-photon effects, lepton universality and, possibly, new physics, while providing simultaneous form factor, and therefore radius, measurements with both muons and electrons.

  11. Nucleocytoplasmic Shuttling of Influenza A Virus Proteins

    Directory of Open Access Journals (Sweden)

    Jing Li

    2015-05-01

    Full Text Available Influenza viruses transcribe and replicate their genomes in the nuclei of infected host cells. The viral ribonucleoprotein (vRNP complex of influenza virus is the essential genetic unit of the virus. The viral proteins play important roles in multiple processes, including virus structural maintenance, mediating nucleocytoplasmic shuttling of the vRNP complex, virus particle assembly, and budding. Nucleocytoplasmic shuttling of viral proteins occurs throughout the entire virus life cycle. This review mainly focuses on matrix protein (M1, nucleoprotein (NP, nonstructural protein (NS1, and nuclear export protein (NEP, summarizing the mechanisms of their nucleocytoplasmic shuttling and the regulation of virus replication through their phosphorylation to further understand the regulation of nucleocytoplasmic shuttling in host adaptation of the viruses.

  12. The space shuttle program: a policy failure?

    Science.gov (United States)

    Logsdon, J M

    1986-05-30

    The 5 January 1972 announcement by President Richard Nixon that the United States would develop during the 1970's a new space transportation system-the space shuttle-has had fundamental impacts on the character of U.S. space activities. In retrospect, it can be argued that the shuttle design chosen was destined to fail to meet many of the policy objectives established for the system; the shuttle's problems in serving as the primary launch vehicle for the United States and in providing routine and cost-effective space transportation are in large part a result of the ways in which compromises were made in the 1971-72 period in order to gain White House and congressional approval to proceed with the program. The decision to develop a space shuttle is an example of a poor quality national commitment to a major technological undertaking.

  13. Space Shuttle Atlantis after RSS rollback

    Science.gov (United States)

    2001-01-01

    On Launch Pad 39A, the Rotating Service Structure has rolled back to reveal Space Shuttle Atlantis poised for launch. Atlantis is carrying the U.S. Laboratory Destiny, a key module in the growth of the International Space Station. Destiny will be attached to the Unity node on the Space Station using the Shuttle's robotic arm. Three spacewalks are required to complete the planned construction work during the 11-day mission. Launch is targeted for 6:11 p.m. EST and the planned landing at KSC Feb. 18 about 1:39 p.m. This mission marks the seventh Shuttle flight to the Space Station, the 23rd flight of Atlantis and the 102nd flight overall in NASA's Space Shuttle program.

  14. The space shuttle program technologies and accomplishments

    CERN Document Server

    Sivolella, Davide

    2017-01-01

    This book tells the story of the Space Shuttle in its many different roles as orbital launch platform, orbital workshop, and science and technology laboratory. It focuses on the technology designed and developed to support the missions of the Space Shuttle program. Each mission is examined, from both the technical and managerial viewpoints. Although outwardly identical, the capabilities of the orbiters in the late years of the program were quite different from those in 1981. Sivolella traces the various improvements and modifications made to the shuttle over the years as part of each mission story. Technically accurate but with a pleasing narrative style and simple explanations of complex engineering concepts, the book provides details of many lesser known concepts, some developed but never flown, and commemorates the ingenuity of NASA and its partners in making each Space Shuttle mission push the boundaries of what we can accomplish in space. Using press kits, original papers, newspaper and magazine articles...

  15. CERN Shuttles - Enlarged Regular Shuttle Services as from 8/02/2010

    CERN Multimedia

    2010-01-01

    As of Monday 8 February 2010, please note the enhancement of the regular shuttle services: - with now two shuttles dedicated to the transportation within and between both CERN sites, Meyrin and Prevessin with bus stop at more buildings - To and from the Geneva airport every hour (from building 500) to complement the TPG bus Y For timetable details, please click here: http://gs-dep.web.cern.ch/gs-dep/groups/sem/ls/RegularShuttleTimetable_Feb2010.htm GS-SEM

  16. Multicavity proton cyclotron accelerator

    Directory of Open Access Journals (Sweden)

    J. L. Hirshfield

    2002-08-01

    Full Text Available A mechanism for acceleration of protons is described, in which energy gain occurs near cyclotron resonance as protons drift through a sequence of rotating-mode TE_{111} cylindrical cavities in a strong nearly uniform axial magnetic field. Cavity resonance frequencies decrease in sequence from one another with a fixed frequency interval Δf between cavities, so that synchronism can be maintained between the rf fields and proton bunches injected at intervals of 1/Δf. An example is presented in which a 122 mA, 1 MeV proton beam is accelerated to 961 MeV using a cascade of eight cavities in an 8.1 T magnetic field, with the first cavity resonant at 120 MHz and with Δf=8 MHz. Average acceleration gradient exceeds 40 MV/m, average effective shunt impedance is 223 MΩ/m, but maximum surface field in the cavities does not exceed 7.2 MV/m. These features occur because protons make many orbital turns in each cavity and thus experience acceleration from each cavity field many times. Longitudinal and transverse stability appear to be intrinsic properties of the acceleration mechanism, and an example to illustrate this is presented. This acceleration concept could be developed into a proton accelerator for a high-power neutron spallation source, such as that required for transmutation of nuclear waste or driving a subcritical fission burner, provided a number of significant practical issues can be addressed.

  17. Cosmonaut Krikalev Views Approaching Space Shuttle Atlantis

    Science.gov (United States)

    2001-01-01

    Cosmonaut Sergei K. Krikalev, flight engineer for Expedition One, is positioned by a porthole aboard the Zvezda Service Module of the International Space Station (ISS) as the Space Shuttle Atlantis approaches for docking to begin several days of joint activities between the two crews. Visible through the window are the crew cabin and forward section of the Shuttle amidst scattered clouds above the Western Pacific. The aft part of the cargo bay stowing the Destiny Laboratory is not visible in this scene.

  18. The physics of proton therapy

    OpenAIRE

    Newhauser, Wayne D; ZHANG, Rui

    2015-01-01

    The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy. This article reviews the basic aspects of the physics of proton therapy, including proton interaction mechanisms, proton transport calculations, the determination of dose from therapeutic and stray radiations, and shielding design. The article discusses underlying processes a...

  19. Space Shuttle Rudder Speed Brake Actuator-A Case Study Probabilistic Fatigue Life and Reliability Analysis

    Science.gov (United States)

    Oswald, Fred B.; Savage, Michael; Zaretsky, Erwin V.

    2015-01-01

    The U.S. Space Shuttle fleet was originally intended to have a life of 100 flights for each vehicle, lasting over a 10-year period, with minimal scheduled maintenance or inspection. The first space shuttle flight was that of the Space Shuttle Columbia (OV-102), launched April 12, 1981. The disaster that destroyed Columbia occurred on its 28th flight, February 1, 2003, nearly 22 years after its first launch. In order to minimize risk of losing another Space Shuttle, a probabilistic life and reliability analysis was conducted for the Space Shuttle rudder/speed brake actuators to determine the number of flights the actuators could sustain. A life and reliability assessment of the actuator gears was performed in two stages: a contact stress fatigue model and a gear tooth bending fatigue model. For the contact stress analysis, the Lundberg-Palmgren bearing life theory was expanded to include gear-surface pitting for the actuator as a system. The mission spectrum of the Space Shuttle rudder/speed brake actuator was combined into equivalent effective hinge moment loads including an actuator input preload for the contact stress fatigue and tooth bending fatigue models. Gear system reliabilities are reported for both models and their combination. Reliability of the actuator bearings was analyzed separately, based on data provided by the actuator manufacturer. As a result of the analysis, the reliability of one half of a single actuator was calculated to be 98.6 percent for 12 flights. Accordingly, each actuator was subsequently limited to 12 flights before removal from service in the Space Shuttle.

  20. Sustainable agriculture

    National Research Council Canada - National Science Library

    Lichtfouse, Eric

    2009-01-01

    ... : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 9 Part I CLIMATE CHANGE Soils and Sustainable Agriculture: A Review : : : : : : : : : : : : : : : : : : : : : : : : : : Rattan Lal 15 Soils and Food Sufficiency...

  1. Sustainable Marketing

    NARCIS (Netherlands)

    Dam, van Y.K.

    2017-01-01

    In this article, three different conceptions of sustainable marketing are discussed and compared. These different conceptions are referred to as social, green, and critical sustainable marketing. Social sustainable marketing follows the logic of demand-driven marketing management and places the

  2. Electrostatic models of electron-driven proton transfer across a lipid membrane

    Energy Technology Data Exchange (ETDEWEB)

    Smirnov, Anatoly Yu; Nori, Franco [Advanced Science Institute, RIKEN, Wako-shi, Saitama, 351-0198 (Japan); Mourokh, Lev G [Department of Physics, Queens College, The City University of New York, Flushing, NY 11367 (United States)

    2011-06-15

    We present two models for electron-driven uphill proton transport across lipid membranes, with the electron energy converted to the proton gradient via the electrostatic interaction. In the first model, associated with the cytochrome c oxidase complex in the inner mitochondria membranes, the electrostatic coupling to the site occupied by an electron lowers the energy level of the proton-binding site, making proton transfer possible. In the second model, roughly describing the redox loop in a nitrate respiration of E. coli bacteria, an electron displaces a proton from the negative side of the membrane to a shuttle, which subsequently diffuses across the membrane and unloads the proton to its positive side. We show that both models can be described by the same approach, which can be significantly simplified if the system is separated into several clusters, with strong Coulomb interaction inside each cluster and weak transfer couplings between them. We derive and solve the equations of motion for the electron and proton creation/annihilation operators, taking into account the appropriate Coulomb terms, tunnel couplings, and the interaction with the environment. For the second model, these equations of motion are solved jointly with a Langevin-type equation for the shuttle position. We obtain expressions for the electron and proton currents and determine their dependence on the electron and proton voltage build-ups, on-site charging energies, reorganization energies, temperature, and other system parameters. We show that the quantum yield in our models can be up to 100% and the power-conversion efficiency can reach 35%.

  3. Journal of Proton Therapy

    Directory of Open Access Journals (Sweden)

    Editorial Office

    2015-01-01

    Full Text Available Journal of Proton Therapy (JPT is an international open access, peer-reviewed journal, which publishes original research, technical reports, reviews, case reports, editorials, and other materials on proton therapy with focus on radiation oncology, medical physics, medical dosimetry, and radiation therapy.No article processing/submission feeNo publication feePeer-review completion within 3-6 weeksImmediate publication after the completion of final author proofreadDOI assignment for each published articleFree access to published articles for all readers without any access barriers or subscriptionThe views and opinions expressed in articles are those of the author/s and do not necessarily reflect the policies of the Journal of Proton Therapy.Authors are encouraged to submit articles for publication in the inaugural issue of the Journal of Proton Therapy by online or email to editor@protonjournal.comOfficial Website of Journal of Proton Therapy: http://www.protonjournal.org/

  4. Proton relativistic model; Modelo relativistico do proton

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Wilson Roberto Barbosa de

    1995-12-31

    In this dissertation, we present a model for the nucleon, which is composed by three relativistic quarks interacting through a contract force. The nucleon wave-function was obtained from the Faddeev equation in the null-plane. The covariance of the model under kinematical null-plane boots is discussed. The electric proton form-factor, calculated from the Faddeev wave-function, was in agreement with the data for low-momentum transfers and described qualitatively the asymptotic region for momentum transfers around 2 GeV. (author) 42 refs., 22 figs., 1 tab.

  5. Success Legacy of the Space Shuttle Program: Changes in Shuttle Post Challenger and Columbia

    Science.gov (United States)

    Jarrell, George

    2010-01-01

    This slide presentation reviews the legacy of successes in the space shuttle program particularly with regards to the changes in the culture of NASA's organization after the Challenger and Columbia accidents and some of the changes to the shuttles that were made manifest as a result of the accidents..

  6. The physics of proton therapy.

    Science.gov (United States)

    Newhauser, Wayne D; Zhang, Rui

    2015-04-21

    The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy. This article reviews the basic aspects of the physics of proton therapy, including proton interaction mechanisms, proton transport calculations, the determination of dose from therapeutic and stray radiations, and shielding design. The article discusses underlying processes as well as selected practical experimental and theoretical methods. We conclude by briefly speculating on possible future areas of research of relevance to the physics of proton therapy.

  7. The physics of proton therapy

    Science.gov (United States)

    Newhauser, Wayne D.; Zhang, Rui

    2015-04-01

    The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy. This article reviews the basic aspects of the physics of proton therapy, including proton interaction mechanisms, proton transport calculations, the determination of dose from therapeutic and stray radiations, and shielding design. The article discusses underlying processes as well as selected practical experimental and theoretical methods. We conclude by briefly speculating on possible future areas of research of relevance to the physics of proton therapy.

  8. Space Shuttle Solid Rocket Booster Debris Assessment

    Science.gov (United States)

    Kendall, Kristin; Kanner, Howard; Yu, Weiping

    2006-01-01

    The Space Shuttle Columbia Accident revealed a fundamental problem of the Space Shuttle Program regarding debris. Prior to the tragedy, the Space Shuttle requirement stated that no debris should be liberated that would jeopardize the flight crew and/or mission success. When the accident investigation determined that a large piece of foam debris was the primary cause of the loss of the shuttle and crew, it became apparent that the risk and scope of - damage that could be caused by certain types of debris, especially - ice and foam, were not fully understood. There was no clear understanding of the materials that could become debris, the path the debris might take during flight, the structures the debris might impact or the damage the impact might cause. In addition to supporting the primary NASA and USA goal of returning the Space Shuttle to flight by understanding the SRB debris environment and capability to withstand that environment, the SRB debris assessment project was divided into four primary tasks that were required to be completed to support the RTF goal. These tasks were (1) debris environment definition, (2) impact testing, (3) model correlation and (4) hardware evaluation. Additionally, the project aligned with USA's corporate goals of safety, customer satisfaction, professional development and fiscal accountability.

  9. Space Shuttle Underside Astronaut Communications Performance Evaluation

    Science.gov (United States)

    Hwu, Shian U.; Dobbins, Justin A.; Loh, Yin-Chung; Kroll, Quin D.; Sham, Catherine C.

    2005-01-01

    The Space Shuttle Ultra High Frequency (UHF) communications system is planned to provide Radio Frequency (RF) coverage for astronauts working underside of the Space Shuttle Orbiter (SSO) for thermal tile inspection and repairing. This study is to assess the Space Shuttle UHF communication performance for astronauts in the shadow region without line-of-sight (LOS) to the Space Shuttle and Space Station UHF antennas. To insure the RF coverage performance at anticipated astronaut worksites, the link margin between the UHF antennas and Extravehicular Activity (EVA) Astronauts with significant vehicle structure blockage was analyzed. A series of near-field measurements were performed using the NASA/JSC Anechoic Chamber Antenna test facilities. Computational investigations were also performed using the electromagnetic modeling techniques. The computer simulation tool based on the Geometrical Theory of Diffraction (GTD) was used to compute the signal strengths. The signal strength was obtained by computing the reflected and diffracted fields along the propagation paths between the transmitting and receiving antennas. Based on the results obtained in this study, RF coverage for UHF communication links was determined for the anticipated astronaut worksite in the shadow region underneath the Space Shuttle.

  10. Intelligent Shuttle Management and Routing Algorithm

    Science.gov (United States)

    Thomas, Toshen M.; Subashanthini, S.

    2017-11-01

    Nowadays, most of the big Universities and campuses have Shuttle cabs running in them to cater the transportational needs of the students and faculties. While some shuttle services ask for a meagre sum to be paid for the usage, no digital payment system is onboard these vehicles to go truly cashless. Even more troublesome is the fact that sometimes during the day, some of these cabs run with bare number of passengers, which can result in unwanted budget loss to the shuttle operator. The main purpose of this paper is to create a system with two types of applications: A web portal and an Android app, to digitize the Shuttle cab industry. This system can be used for digital cashless payment feature, tracking passengers, tracking cabs and more importantly, manage the number of shuttle cabs in every route to maximize profit. This project is built upon an ASP.NET website connected to a cloud service along with an Android app that tracks and reads the passengers ID using an attached barcode reader along with the current GPS coordinates, and sends these data to the cloud for processing using the phone’s internet connectivity.

  11. Recent space shuttle observations of the South Atlantic anomaly and the radiation belt models

    Science.gov (United States)

    Konradi, A.; Badhwar, G. D.; Braby, L. A.

    1994-01-01

    Active ingredients consisting of Tissue Equivalent Proportional Counter (TEPC) and a Proton and Heavy Ion Detector (PHIDE) have been carried on a number of Space Shuttle flights. These instruments have allowed us to map out parts of the South Atlantic Particle Anomaly (SAA) and to compare some of it's features with predictions of the AP-8 energetic proton flux models. We have observed that consistent with the generally observed westward drift of the surface features of the terrestial magnetic field of the SAA has moved west by about 6.9 degrees longitude between the epoch year 1970 of the AP-8 solar maximum model and the Space Shuttle observations made twenty years later. However, calculations indicate that except for relatively brief periods following very large magnetic storms the SAA seems to occupy the same position in L-space as in 1970. After the great storm of 24 March 1991 reconfiguration of the inner radiation belt and/or proton injection into the inner belt, a second energetic proton belt was observed to form at approximately equal to 2. As confirmed by a subsequent flight observations, this belt was shown to persist at least for six months. Our measurements also indicate an upward shift in the L location of the primary belt from L = 1.4 to L = 1.5. In addition we confirm through direct real time observations the existence and the approximate magnitude of the East-West effect. If the need exists for improved and updated radiation belt models in the Space Station era, these observations point out the specific features that should be considered and incorporated when this task is undertaken.

  12. Proton tunneling in solids

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, J.

    1998-10-01

    The tunneling rate of the proton and its isotopes between interstitial sites in solids is studied theoretically. The phonons and/or the electrons in the solid have two effects on the tunneling phenomenon. First, they suppress the transfer integral between two neighbouring states. Second, they give rise to a finite lifetime of the proton state. Usually the second effect is large and the tunneling probability per unit time (tunneling rate) can be defined. In some cases, however, a coherent tunneling is expected and actually observed. (author)

  13. A New Era of Space Shuttle

    Directory of Open Access Journals (Sweden)

    Sun Kyu Kim

    1985-06-01

    Full Text Available The U.S. Space Shuttle represents the beginning of a new era in transportation and is the critical element in the industrialization of the near-Earth-space. Most of its flights are dedicated to reducing costs of launching commercial satellites. However, it provides a microgravity environment for processing unique and improved materials which is generating great interest in both civilian and military sectors. The space shuttle is also the necessary step in establishing a permanent space station which could host materials analysis laboratories and commercial processing facilities. This paper reviews the different elements of the space shuttle transportation system, a typical mission scenario, and discusses current activities in materials processing in space.

  14. Orbital impacts and the space shuttle windshield

    Science.gov (United States)

    Edelstein, Karen S.

    1995-06-01

    The Space Transportation System (STS) fleet has flown more than sixty missions over the fourteen years since its first flight. As a result of encounters with on-orbit particulates (space debris and micrometeoroids), 177 impact features (chips) have been found on the STS outer windows (through STS-65). Forty-five of the damages were large enough to warrant replacement of the window. NASA's orbital operations and vehicle inspection procedures have chnaged over the history of the shuttle program, in response to concerns about the orbital environment and the cost of maintaining the space shuttle. These programmatic issues will be discussed, including safety concerns, maintenance issues, inspection procedures, and flight rule changes. Examples of orbital debris impacts to the shuttle windows will be provided. There will also be a brief discussion of the impact properties of glass and what design changes have been considered to improve the impact properties of the windows.

  15. Shuttle Case Study Collection Website Development

    Science.gov (United States)

    Ransom, Khadijah S.; Johnson, Grace K.

    2012-01-01

    As a continuation from summer 2012, the Shuttle Case Study Collection has been developed using lessons learned documented by NASA engineers, analysts, and contractors. Decades of information related to processing and launching the Space Shuttle is gathered into a single database to provide educators with an alternative means to teach real-world engineering processes. The goal is to provide additional engineering materials that enhance critical thinking, decision making, and problem solving skills. During this second phase of the project, the Shuttle Case Study Collection website was developed. Extensive HTML coding to link downloadable documents, videos, and images was required, as was training to learn NASA's Content Management System (CMS) for website design. As the final stage of the collection development, the website is designed to allow for distribution of information to the public as well as for case study report submissions from other educators online.

  16. Space Shuttle Pinhole Formation Mechanism Studies

    Science.gov (United States)

    Jacobson, Nathan S.

    1998-01-01

    Pinholes have been observed to form on the wing leading edge of the space shuttle after about 10-15 flights. In this report we expand upon previous observations by Christensen (1) that these pinholes often form along cracks and are associated with a locally zinc-rich area. The zinc appears to come from weathering and peeling paint on the launch structure. Three types of experimental examinations are performed to understand this issue further: (A) Detailed microstructural examination of actual shuttle pinholes (B) Mass spectrometric studies of coupons containing, actual shuttle pinholes and (C) Laboratory furnace studies of ZnO/SiC reactions and ZnO/SiC protected carbon/carbon reaction. On basis of these observations we present a detailed mechanism of pinhole formation due to formation of a corrosive ZnO-Na-2-O-SiO2 ternary glass, which flows into existing cracks and enlarges them.

  17. Sustainable Disruptions

    DEFF Research Database (Denmark)

    Friis, Silje Alberthe Kamille; Kjær, Lykke Bloch

    2016-01-01

    Since 2012 the Sustainable Disruptions (SD) project at the Laboratory for Sustainability at Design School Kolding (DK) has developed and tested a set of design thinking tools, specifically targeting the barriers to economically, socially, and environmentally sustainable business development....... The tools have been applied in practice in collaboration with 11 small and medium sized companies (SMEs). The study investigates these approaches to further understand how design thinking can contribute to sustainable transition in a business context. The study and the findings are relevant to organizations...... invested in the issue of sustainable business development, in particular the leaders and employees of SMEs, but also to design education seeking new ways to consciously handle and teach the complexity inherent in sustainable transformation. Findings indicate that the SD design thinking approach contributes...

  18. Proton Radiography (pRad)

    Data.gov (United States)

    Federal Laboratory Consortium — The proton radiography project has used 800 MeV protons provided by the LANSCE accelerator facility at LANL, to diagnose more than 300 dynamic experiments in support...

  19. Proton therapy in clinical practice

    Science.gov (United States)

    Liu, Hui; Chang, Joe Y.

    2011-01-01

    Radiation dose escalation and acceleration improves local control but also increases toxicity. Proton radiation is an emerging therapy for localized cancers that is being sought with increasing frequency by patients. Compared with photon therapy, proton therapy spares more critical structures due to its unique physics. The physical properties of a proton beam make it ideal for clinical applications. By modulating the Bragg peak of protons in energy and time, a conformal radiation dose with or without intensity modulation can be delivered to the target while sparing the surrounding normal tissues. Thus, proton therapy is ideal when organ preservation is a priority. However, protons are more sensitive to organ motion and anatomy changes compared with photons. In this article, we review practical issues of proton therapy, describe its image-guided treatment planning and delivery, discuss clinical outcome for cancer patients, and suggest challenges and the future development of proton therapy. PMID:21527064

  20. STS-62 Space Shuttle mission report

    Science.gov (United States)

    Fricke, Robert W., Jr.

    1994-05-01

    The STS-62 Space Shuttle Program Mission Report summarizes the Payload activities as well as the Orbiter, External Tank (ET), Solid Rocket Booster (SRB), Redesigned Solid Rocket Motor (RSRM), and the Space Shuttle main engine (SSHE) systems performance during the sixty-first flight of the Space Shuttle Program and sixteenth flight of the Orbiter vehicle Columbia (OV-102). In addition to the Orbiter, the flight vehicle consisted of an ET designated as ET-62; three SSME's which were designated as serial numbers 2031, 2109, and 2029 in positions 1, 2, and 3, respectively; and two SRB's which were designated BI-064. The RSRM's that were installed in each SRB were designated as 360L036A (lightweight) for the left SRB, and 36OWO36B (welterweight) for the right SRB. This STS-62 Space Shuttle Program Mission Report fulfills the Space Shuttle Program requirement as documented in NSTS 07700, Volume 8, Appendix E. That document requires that each major organizational element supporting the Program report the results of its hardware evaluation and mission performance plus identify all related in-flight anomalies. The primary objectives of the STS-62 mission were to perform the operations of the United States Microgravity Payload-2 (USMP-2) and the Office of Aeronautics and Space Technology-2 (OAST-2) payload. The secondary objectives of this flight were to perform the operations of the Dexterous End Effector (DEE), the Shuttle Solar Backscatter Ultraviolet/A (SSBUV/A), the Limited Duration Space Environment Candidate Material Exposure (LDCE), the Advanced Protein Crystal Growth (APCG), the Physiological Systems Experiments (PSE), the Commercial Protein Crystal Growth (CPCG), the Commercial Generic Bioprocessing Apparatus (CGBA), the Middeck Zero-Gravity Dynamics Experiment (MODE), the Bioreactor Demonstration System (BDS), the Air Force Maui Optical Site Calibration Test (AMOS), and the Auroral Photography Experiment (APE-B).

  1. Computational sustainability

    CERN Document Server

    Kersting, Kristian; Morik, Katharina

    2016-01-01

    The book at hand gives an overview of the state of the art research in Computational Sustainability as well as case studies of different application scenarios. This covers topics such as renewable energy supply, energy storage and e-mobility, efficiency in data centers and networks, sustainable food and water supply, sustainable health, industrial production and quality, etc. The book describes computational methods and possible application scenarios.

  2. Sustainable transformation

    DEFF Research Database (Denmark)

    Andersen, Nicolai Bo

    This paper is about sustainable transformation with a particular focus on listed buildings. It is based on the notion that sustainability is not just a question of energy conditions, but also about the building being robust. Robust architecture means that the building can be maintained and rebuilt...... theoretical lenses. It is proposed that three parameters concerning the ꞌtransformabilityꞌ of the building can contribute to a more nuanced understanding of sustainable transformation: technical aspects, programmatic requirements and narrative value. It is proposed that the concept of ꞌsustainable...

  3. Protons Trigger Mitochondrial Flashes.

    Science.gov (United States)

    Wang, Xianhua; Zhang, Xing; Huang, Zhanglong; Wu, Di; Liu, Beibei; Zhang, Rufeng; Yin, Rongkang; Hou, Tingting; Jian, Chongshu; Xu, Jiejia; Zhao, Yan; Wang, Yanru; Gao, Feng; Cheng, Heping

    2016-07-26

    Emerging evidence indicates that mitochondrial flashes (mitoflashes) are highly conserved elemental mitochondrial signaling events. However, which signal controls their ignition and how they are integrated with other mitochondrial signals and functions remain elusive. In this study, we aimed to further delineate the signal components of the mitoflash and determine the mitoflash trigger mechanism. Using multiple biosensors and chemical probes as well as label-free autofluorescence, we found that the mitoflash reflects chemical and electrical excitation at the single-organelle level, comprising bursting superoxide production, oxidative redox shift, and matrix alkalinization as well as transient membrane depolarization. Both electroneutral H(+)/K(+) or H(+)/Na(+) antiport and matrix proton uncaging elicited immediate and robust mitoflash responses over a broad dynamic range in cardiomyocytes and HeLa cells. However, charge-uncompensated proton transport, which depolarizes mitochondria, caused the opposite effect, and steady matrix acidification mildly inhibited mitoflashes. Based on a numerical simulation, we estimated a mean proton lifetime of 1.42 ns and diffusion distance of 2.06 nm in the matrix. We conclude that nanodomain protons act as a novel, to our knowledge, trigger of mitoflashes in energized mitochondria. This finding suggests that mitoflash genesis is functionally and mechanistically integrated with mitochondrial energy metabolism. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  4. Proton-pump inhibitors

    African Journals Online (AJOL)

    Proton-pump inhibitors (PPIs) work by binding irreversibly to the. H+/K+-ATPase pump of the parietal cell, leading to inhibition of acid production in approximately 70% of active pumps.1The result is a dramatic increase in gastric pH mitigating the deleterious effects of acid in gastro-oesophageal reflux disease (GORD) and.

  5. Proton transfer events in GFP

    NARCIS (Netherlands)

    Di Donato, M.; van Wilderen, L.J.; van Stokkum, I.H.M.; Stuart, T. C.; Kennis, J.T.M.; Hellingwerf, K.J.; van Grondelle, R.; Groot, M.L.

    2011-01-01

    Proton transfer is one of the most important elementary processes in biology. Green fluorescent protein (GFP) serves as an important model system to elucidate the mechanistic details of this reaction, because in GFP proton transfer can be induced by light absorption. Illumination initiates proton

  6. Proton radiography for clinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Talamonti, C., E-mail: cinzia.talamonti@unifi.i [Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, v.le Morgagni 85, I-50134 Firenze (Italy); INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Azienda Ospedaliero-Universitaria Careggi, v.le Morgagni 85, I-50134 Firenze (Italy); Reggioli, V. [Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, v.le Morgagni 85, I-50134 Firenze (Italy); Bruzzi, M. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Dipartimento di Energetica, Universita degli Studi di Firenze, via S. Marta 3, I-50139 Firenze (Italy); Bucciolini, M. [Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, v.le Morgagni 85, I-50134 Firenze (Italy); INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Azienda Ospedaliero-Universitaria Careggi, v.le Morgagni 85, I-50134 Firenze (Italy); Civinini, C. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Marrazzo, L. [Azienda Ospedaliero-Universitaria Careggi, v.le Morgagni 85, I-50134 Firenze (Italy); Menichelli, D. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Finland) (Italy); Dipartimento di Energetica, Universita degli Studi di Firenze, via S. Marta 3, I-50139 Firenze (Italy); Pallotta, S. [Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, v.le Morgagni 85, I-50134 Firenze (Italy); INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Azienda Ospedaliero-Universitaria Careggi, v.le Morgagni 85, I-50134 Firenze (Italy); Randazzo, N. [INFN, sezione di Catania, via S. Sofia 64, I-95123 Catania (Italy); Sipala, V. [INFN, sezione di Catania, via S. Sofia 64, I-95123 Catania (Italy); Dipartimento di Fisica, Universita degli Studi di Catania, via S. Sofia 64, I-95123 Catania (Italy)

    2010-01-11

    Proton imaging is not yet applied as a clinical routine, although its advantages have been demonstrated. In the context of quality assurance in proton therapy, proton images can be used to verify the correct positioning of the patient and to control the range of protons. Proton computed tomography (pCT) is a 3D imaging method appropriate for planning and verification of proton radiation treatments, because it allows evaluating the distributions of proton stopping power within the tissues and can be directly utilized when the patient is in the actual treatment position. The aim of the PRoton IMAging experiment, supported by INFN, and the PRIN 2006 project, supported by MIUR, is to realize a proton computed radiography (pCR) prototype for reconstruction of proton images from a single projection in order to validate the technique with pre-clinical studies and, eventually, to conceive the configuration of a complete pCT system. A preliminary experiment performed at the 250 MeV proton synchrotron of Loma Linda University Medical Center (LLUMC) allowed acquisition of experimental data before the completion of PRIMA project's prototype. In this paper, the results of the LLUMC experiment are reported and the reconstruction of proton images of two phantoms is discussed.

  7. Proton radiography and tomography with application to proton therapy

    Science.gov (United States)

    Allinson, N M; Evans, P M

    2015-01-01

    Proton radiography and tomography have long promised benefit for proton therapy. Their first suggestion was in the early 1960s and the first published proton radiographs and CT images appeared in the late 1960s and 1970s, respectively. More than just providing anatomical images, proton transmission imaging provides the potential for the more accurate estimation of stopping-power ratio inside a patient and hence improved treatment planning and verification. With the recent explosion in growth of clinical proton therapy facilities, the time is perhaps ripe for the imaging modality to come to the fore. Yet many technical challenges remain to be solved before proton CT scanners become commonplace in the clinic. Research and development in this field is currently more active than at any time with several prototype designs emerging. This review introduces the principles of proton radiography and tomography, their historical developments, the raft of modern prototype systems and the primary design issues. PMID:26043157

  8. Sustainable Transportation

    DEFF Research Database (Denmark)

    Hall, Ralph P.; Gudmundsson, Henrik; Marsden, Greg

    2014-01-01

    that relate to the construction and maintenance of transportation infrastructure and the operation or use of the different transportation modes. The concept of sustainable transportation emerged in response to these concerns as part of the broader notion of sustainable development. Given the transportation...

  9. Sustaining dairy

    NARCIS (Netherlands)

    Villarreal Herrera, Georgina

    2017-01-01

    Dairy in Europe has undergone many changes in the last few years—the abolition of milk production quotas being a fundamental one. This study explores these changes in relation to the sustained social and environmental viability of the sector and how dairy processors' sustainability

  10. Sustainable Universities

    DEFF Research Database (Denmark)

    Grindsted, Thomas Skou

    2011-01-01

    . Declarations tend to have impact on three trends. Firstly, there is emerging international consensus on the university’s role and function in relation to sustainable development; secondly, the emergence of national legislation, and thirdly, an emerging international competition to be leader in sustainable...... campus performance....

  11. Sustainable Transition

    DEFF Research Database (Denmark)

    Hansen, Ole Erik; Søndergård, Bent

    2014-01-01

    of agendas/vision, technologies, actors and institutions in the emergent design of an urban mobility system based on an electric car sharing system. Why. Designing for sustainability is a fundamental challenge for future design practices; designers have to obtain an ability to contribute to sustainable...

  12. Sustainable Learning

    Science.gov (United States)

    Cadwell, Louise; Dillon, Robert

    2011-01-01

    Green schools have moved into a new era that focuses on building a culture of sustainability in every aspect of learning in schools. In the early stages of sustainability education, the focus was on recycling and turning off the lights. Now, students and adults together are moving into the areas of advocacy and action that are based on a deep…

  13. Observations and predictions of secondary neutrons on space shuttle and aircraft

    Science.gov (United States)

    Truscott, P. R.; Dyer, C. S.; Evans, H. E.; Sims, A. J.; Peerless, C. L.; Knight, P. R.; Cosby, M.; Flatman, J. C.; Comber, C.; Hammond, N. D. A.

    The Cosmic Radiation Effects and Activation Monitor has flown on six Shuttle flights between September 1991 and February 1995 covering the full range of inclinations as well as altitudes between 220 and 570 km, while a version has flown at supersonic altitudes on Concorde between 1988 and 1992 and at subsonic altitudes on a SAS Boeing 767 between May and August 1993. The Shuttle flights have included passive packages in addition to the active cosmic ray monitor which comprises an array of pin diodes. These are positioned at a number of locations to investigate the influence of shielding and local materials. Use of both metal activation foils and scintillator crystals enables neutron fluences to be inferred from the induced radioactivity which is observed on return to Earth. Supporting radiation transport calculations are performed to predict secondary neutron spectra and the energy deposition due o nuclear reactions in silicon pin diodes and the induced radioactivity in the various scintillator crystals. The wide variety of orbital and atmospheric locations enables investigation of the influence of shielding on cosmic ray, trapped proton and solar flare proton spectra.

  14. AMS gets lift on space shuttle Discovery

    CERN Multimedia

    2009-01-01

    AMS-02, the CERN-recognized experiment that will seek dark matter, missing matter and antimatter in Space aboard the International Space Station (ISS), has recently got the green light to be part of the STS-134 NASA mission in 2010. Installation of AMS detectors in the Prévessin experiment hall.In a recent press release, NASA announced that the last or last-but-one mission of the Space Shuttle programme would be the one that will deliver AMS, the Alpha Magnetic Spectrometer, to the International Space Station. The Space Shuttle Discovery is due to lift off in July 2010 from Kennedy Space Center and its mission will include the installation of AMS to the exterior of the space station, using both the shuttle and station arms. "It wasn’t easy to get a lift on the Space Shuttle from the Bush administration," says professor Samuel Ting, spokesperson of the experiment, "since during his administration all the funds for space research w...

  15. Shuttle Transportation System Case-Study Development

    Science.gov (United States)

    Ransom, Khadijah

    2012-01-01

    A case-study collection was developed for NASA's Space Shuttle Program. Using lessons learned and documented by NASA KSC engineers, analysts, and contractors, decades of information related to processing and launching the Space Shuttle was gathered into a single database. The goal was to provide educators with an alternative means to teach real-world engineering processes and to enhance critical thinking, decision making, and problem solving skills. Suggested formats were created to assist both external educators and internal NASA employees to develop and contribute their own case-study reports to share with other educators and students. Via group project, class discussion, or open-ended research format, students will be introduced to the unique decision making process related to Shuttle missions and development. Teaching notes, images, and related documents will be made accessible to the public for presentation of Space Shuttle reports. Lessons investigated included the engine cutoff (ECO) sensor anomaly which occurred during mission STS-114. Students will be presented with general mission infom1ation as well as an explanation of ECO sensors. The project will conclude with the design of a website that allows for distribution of information to the public as well as case-study report submissions from other educators online.

  16. Current and Current Fluctuations in Quantum Shuttles

    DEFF Research Database (Denmark)

    Jauho, Antti-Pekka; Flindt, Christian; Novotny, Tomas

    2005-01-01

    We review the properties of electron shuttles, i.e., nanoelectromechanical devices that transport electrons one by one by utilizing a combination of electronic and mechanical degrees of freedom. We focus on the extreme quantum limit, where the mechanical motion is quantized. We introduce the main...

  17. Shuttle Operational Test and Scientific Investigations

    Science.gov (United States)

    Stonesifer, J. C.

    1985-01-01

    The Detailed Test Objectives (DTOs) originated as a test or measurement made to verify the function of a vehicle system for certification of a vehicle system. The Detailed Supplementary Objectives (DSOs) are a demonstration or test which has a lower priority than a DTO. The criteria for inclusion on space shuttle mission is discussed.

  18. Shuttle Imaging Radar Survey Mission C

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Spaceborne Imaging Radar-C (SIR-C) was part of an imaging radar system that was flown on board two Space Shuttle flights (9 - 20 April, 1994 and 30 September - 11...

  19. Laser contouring of Space Shuttle tiles

    Science.gov (United States)

    Bishop, P. J.; Minardi, A.; He, Mingli; Shelton, Bret

    Straight through and partial cuts were made in fibrous silicon-based ceramic insulation materials (used on the Space Shuttle) to determine the feasibility of laser machining. Experimental results were accumulated from over 800 exposures to determine the belt conditions for cutting. Laser intensity, feedrate, and other parameters were varied to determine conditions for cutting and are discussed in the paper.

  20. Antideuteron production in proton-proton and proton-nucleus collisions

    OpenAIRE

    Duperray, R. P.; K. V. Protasov; Voronin, A. Yu.(P.N. Lebedev Physical Institute, 53 Leninsky Prospekt, 117924 Moscow, Russia)

    2002-01-01

    The experimental data of the antideuteron production in proton-proton and proton-nucleus collisions are analyzed within a simple model based on the diagrammatic approach to the coalescence model. This model is shown to be able to reproduce most of existing data without any additional parameter.

  1. Shuttle Repair Tools Automate Vehicle Maintenance

    Science.gov (United States)

    2013-01-01

    Successfully building, flying, and maintaining the space shuttles was an immensely complex job that required a high level of detailed, precise engineering. After each shuttle landed, it entered a maintenance, repair, and overhaul (MRO) phase. Each system was thoroughly checked and tested, and worn or damaged parts replaced, before the shuttle was rolled out for its next mission. During the MRO period, workers needed to record exactly what needed replacing and why, as well as follow precise guidelines and procedures in making their repairs. That meant traceability, and with it lots of paperwork. In 2007, the number of reports generated during electrical system repairs was getting out of hand-placing among the top three systems in terms of paperwork volume. Repair specialists at Kennedy Space Center were unhappy spending so much time at a desk and so little time actually working on the shuttle. "Engineers weren't spending their time doing technical work," says Joseph Schuh, an electrical engineer at Kennedy. "Instead, they were busy with repetitive, time-consuming processes that, while important in their own right, provided a low return on time invested." The strain of such inefficiency was bad enough that slow electrical repairs jeopardized rollout on several occasions. Knowing there had to be a way to streamline operations, Kennedy asked Martin Belson, a project manager with 30 years experience as an aerospace contractor, to co-lead a team in developing software that would reduce the effort required to document shuttle repairs. The result was System Maintenance Automated Repair Tasks (SMART) software. SMART is a tool for aggregating and applying information on every aspect of repairs, from procedures and instructions to a vehicle s troubleshooting history. Drawing on that data, SMART largely automates the processes of generating repair instructions and post-repair paperwork. In the case of the space shuttle, this meant that SMART had 30 years worth of operations

  2. Rockwell International art concept view on proposed Shuttle payloads

    Science.gov (United States)

    1982-01-01

    Rockwell International art concept view on proposed Shuttle payloads. View is of the Solar Max Mission. The shuttle is in orbit with the remote manipulator system (RMS) grappling the satellite into place.

  3. Shuttle SBUV (SSBUV) Solar Spectral Irradiance V008

    Data.gov (United States)

    National Aeronautics and Space Administration — The Shuttle Solar Backscatter Ultraviolet (SSBUV) level-2 irradiance data are available for eight space shuttle missions flown between 1989 and 1996. SSBUV, a...

  4. Semiconductor surface physics research in the Space Shuttle orbit

    Energy Technology Data Exchange (ETDEWEB)

    Lindau, I.; Spicer, W.E.

    1977-11-01

    The prospects for surface physics research on semiconductors with the Space Shuttle are summarized. The effect of residual gases and solar radiation outside the Shuttle on the semiconductor-surface electronic properties are assessed.

  5. Proton conduction in water ices under an electric field.

    Science.gov (United States)

    Cassone, Giuseppe; Giaquinta, Paolo V; Saija, Franz; Saitta, A Marco

    2014-04-24

    We report on a first-principles study of the effects produced by a static electric field on proton conduction in ordinary hexagonal ice (phase Ih) and in its proton-ordered counterpart (phase XI). We performed ab initio molecular dynamics simulations of both phases and investigated the effects produced by the field on the structure of the material, with particular attention paid to the phenomenon of proton transfer. We observed that in ice Ih molecules start to dissociate for field intensities around 0.25 V/Å, as in liquid water, whereas fields stronger than 0.36 V/Å are needed to induce a permanent proton flow. In contrast, in ice XI, electric fields as intense as 0.22 V/Å are already able to induce and sustain, through correlated proton jumps, an ionic current; this behavior suggests, somewhat counterintuitively, that the ordering of protons favors the autoprotolysis phenomenon. However, the same is not true for static conductivities. In fact, both crystalline phases show an ohmic behavior in the conduction regime, but the conductivity of ice Ih turns out to be larger than that of ice XI. We finally discuss the qualitative and quantitative importance of the conspicuous concentration of ionic defects generated by intense electric fields in determining the value of the conductivity, also through a comparison with the experimental data available for saline ices.

  6. Operation of the preclinical head scanner for proton CT

    Energy Technology Data Exchange (ETDEWEB)

    Sadrozinski, H.F.-W., E-mail: hartmut@ucsc.edu [SCIPP, U.C. Santa Cruz, Santa Cruz, CA 95064 (United States); Geoghegan, T.; Harvey, E.; Johnson, R.P.; Plautz, T.E.; Zatserklyaniy, A. [SCIPP, U.C. Santa Cruz, Santa Cruz, CA 95064 (United States); Bashkirov, V.; Hurley, R.F.; Piersimoni, P.; Schulte, R.W. [Division of Radiation Research, Loma Linda University, Loma Linda, CA 92354 (United States); Karbasi, P.; Schubert, K.E.; Schultze, B. [School of Engineering and Computer Science, Baylor University, Waco, TX 76798 (United States); Giacometti, V. [Center for Medical Radiation Physics, University of Wollongong, NSW (Australia)

    2016-09-21

    We report on the operation and performance tests of a preclinical head scanner developed for proton computed tomography (pCT). After extensive preclinical testing, pCT is intended to be employed in support of proton therapy treatment planning and pre-treatment verification in patients undergoing particle-beam therapy. In order to assess the performance of the scanner, we have performed CT scans with 200 MeV protons from both the synchrotron of the Loma Linda University Medical Center (LLUMC) and the cyclotron of the Northwestern Medicine Chicago Proton Center (NMCPC). The very high sustained rate of data acquisition, exceeding one million protons per second, allowed a full 360° scan to be completed in less than 7 min. The reconstruction of various phantoms verified accurate reconstruction of the proton relative stopping power (RSP) and the spatial resolution in a variety of materials. The dose for an image with better than 1% uncertainty in the RSP is found to be close to 1 mGy.

  7. Proton therapy in the clinic.

    Science.gov (United States)

    DeLaney, Thomas F

    2011-01-01

    The clinical advantage for proton radiotherapy over photon approaches is the marked reduction in integral dose to the patient, due to the absence of exit dose beyond the proton Bragg peak. The integral dose with protons is approximately 60% lower than that with any external beam photon technique. Pediatric patients, because of their developing normal tissues and anticipated length of remaining life, are likely to have the maximum clinical gain with the use of protons. Proton therapy may also allow treatment of some adult tumors to much more effective doses, because of normal tissue sparing distal to the tumor. Currently, the most commonly available proton treatment technology uses 3D conformal approaches based on (a) distal range modulation, (b) passive scattering of the proton beam in its x- and y-axes, and (c) lateral beam-shaping. It is anticipated that magnetic pencil beam scanning will become the dominant mode of proton delivery in the future, which will lower neutron scatter associated with passively scattered beam lines, reduce the need for expensive beam-shaping devices, and allow intensity-modulated proton radiotherapy. Proton treatment plans are more sensitive to variations in tumor size and normal tissue changes over the course of treatment than photon plans, and it is expected that adaptive radiation therapy will be increasingly important for proton therapy as well. While impressive treatment results have been reported with protons, their cost is higher than for photon IMRT. Hence, protons should ideally be employed for anatomic sites and tumors not well treated with photons. While protons appear cost-effective for pediatric tumors, their cost-effectiveness for treatment of some adult tumors, such as prostate cancer, is uncertain. Comparative studies have been proposed or are in progress to more rigorously assess their value for a variety of sites. The utility of proton therapy will be enhanced by technological developments that reduce its cost

  8. Fast proton decay

    Science.gov (United States)

    Li, Tianjun; Nanopoulos, Dimitri V.; Walker, Joel W.

    2010-10-01

    We consider proton decay in the testable flipped SU(5)×U(1)X models with TeV-scale vector-like particles which can be realized in free fermionic string constructions and F-theory model building. We significantly improve upon the determination of light threshold effects from prior studies, and perform a fresh calculation of the second loop for the process p→eπ from the heavy gauge boson exchange. The cumulative result is comparatively fast proton decay, with a majority of the most plausible parameter space within reach of the future Hyper-Kamiokande and DUSEL experiments. Because the TeV-scale vector-like particles can be produced at the LHC, we predict a strong correlation between the most exciting particle physics experiments of the coming decade.

  9. The proton radius puzzle

    Science.gov (United States)

    Antognini, A.; Amaro, F. D.; Biraben, F.; Cardoso, J. M. R.; Covita, D. S.; Dax, A.; Dhawan, S.; Fernandes, L. M. P.; Giesen, A.; Graf, T.; Hänsch, T. W.; Indelicato, P.; Julien, L.; Kao, C.-Y.; Knowles, P.; Kottmann, F.; Le Bigot, E.-O.; Liu, Y.-W.; Lopes, J. A. M.; Ludhova, L.; Monteiro, C. M. B.; Mulhauser, F.; Nebel, T.; Nez, F.; Rabinowitz, P.; dos Santos, J. M. F.; Schaller, L. A.; Schuhmann, K.; Schwob, C.; Taqqu, D.; Veloso, J. F. C. A.; Pohl, R.

    2011-09-01

    By means of pulsed laser spectroscopy applied to muonic hydrogen (μ- p) we have measured the 2SF = 11/2 - 2PF = 23/2 transition frequency to be 49881.88(76) GHz [1]. By comparing this measurement with its theoretical prediction [2, 3, 4, 5, 6, 7] based on bound-state QED we have determined a proton radius value of rp = 0.84184(67) fm. This new value differs by 5.0 standard deviations from the COD ATA value of 0.8768(69) fm [8], and 3 standard deviation from the e-p scattering results of 0.897(18) fm [9]. The observed discrepancy may arise from a computational mistake of the energy levels in μp or H, or a fundamental problem in bound-state QED, an unknown effect related to the proton or the muon, or an experimental error.

  10. Pion, Kaon, Proton and Antiproton Production in Proton-Proton Collisions

    Science.gov (United States)

    Norbury, John W.; Blattnig, Steve R.

    2008-01-01

    Inclusive pion, kaon, proton, and antiproton production from proton-proton collisions is studied at a variety of proton energies. Various available parameterizations of Lorentz-invariant differential cross sections as a function of transverse momentum and rapidity are compared with experimental data. The Badhwar and Alper parameterizations are moderately satisfactory for charged pion production. The Badhwar parameterization provides the best fit for charged kaon production. For proton production, the Alper parameterization is best, and for antiproton production the Carey parameterization works best. However, no parameterization is able to fully account for all the data.

  11. Proton conducting cerate ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, G.W.; Pederson, L.R.; Armstrong, T.R.; Bates, J.L.; Weber, W.J. [Pacific Northwest Lab., Richland, WA (United States)

    1995-08-01

    Cerate perovskites of the general formula AM{sub x}Ce{sub 1-x}O{sub 3-{delta}}, where A = Sr or Ba and where M = Gd, Nd, Y, Yb or other rare earth dopant, are known to conduct a protonic current. Such materials may be useful as the electrolyte in a solid oxide fuel cell operating at intermediate temperatures, as an electrochemical hydrogen separation membrane, or as a hydrogen sensor. Conduction mechanisms in these materials were evaluated using dc cyclic voltammetry and mass spectrometry, allowing currents and activation energies for proton, electron, and oxygen ion contributions to the total current to be determined. For SrYb{sub 0.05}Ce{sub 0.95}O{sub 3-{delta}}, one of the best and most environmentally stable compositions, proton conduction followed two different mechanisms: a low temperature process, characterized by an activation energy of 0.42{+-}0.04 eV, and a high temperature process, characterized by an activation energy of 1.38{+-}0.13 eV. It is believed that the low temperature process is dominated by grain boundary conduction while bulk conduction is responsible for the high temperature process. The activation energy for oxygen ion conduction (0.97{+-}0.10 eV) agrees well with other oxygen conductors, while that for electronic conduction, 0.90{+-}0.09 eV, is affected by a temperature-dependent electron carrier concentration. Evaluated by direct measurement of mass flux through a dense ceramic with an applied dc field, oxygen ions were determined to be the majority charge carrier except at the lowest temperatures, followed by electrons and then protons.

  12. Heavy quarks in proton

    CERN Document Server

    AUTHOR|(SzGeCERN)655637

    The measurement of prompt photon associated with a b jet in proton-proton interactions can provide us insight into the inner structure of proton. This is because precision of determination of parton distribution functions of b quark and gluon can be increased by such a measurement. The measurement of cross-section of prompt photon associated with a b jet (process $pp\\longrightarrow \\gamma + b + X$) at $\\sqrt{s}$= 8 TeV with the ATLAS detector is presented. Full 8 TeV dataset collected by ATLAS during the year 2012 was used in this analysis. Corresponding integrated luminosity is 20.3 $fb^{-1}$. Fiducial differential cross-section as a function of photon transverse momentum at particle level was extracted from data and compared with the prediction of leading order event generator Pythia 8. Cross-section extracted from data is normalised independently on the Monte Carlo prediction. Values of data distribution lie above Monte Carlo values. The difference can be explained by presence of higher order effects not ...

  13. Economic analysis of the space shuttle system, volume 1

    Science.gov (United States)

    1972-01-01

    An economic analysis of the space shuttle system is presented. The analysis is based on economic benefits, recurring costs, non-recurring costs, and ecomomic tradeoff functions. The most economic space shuttle configuration is determined on the basis of: (1) objectives of reusable space transportation system, (2) various space transportation systems considered and (3) alternative space shuttle systems.

  14. Sustainable consumption

    DEFF Research Database (Denmark)

    Prothero, Andrea; Dobscha, Susan; Freund, Jim

    2011-01-01

    This essay explores sustainable consumption and considers possible roles for marketing and consumer researchers and public policy makers in addressing the many sustainability challenges that pervade our planet. Future research approaches to this interdisciplinary topic need to be comprehensive...... and systematic and will benefit from a variety of different perspectives. There are a number of opportunities for future research, and three areas are explored in detail. First, the essay considers the inconsistency between the attitudes and behaviors of consumers with respect to sustainability; next, the agenda...... is broadened to explore the role of individual citizens in society; and finally, a macro institutional approach to fostering sustainability is explored. Each of these areas is examined in detail and possible research avenues and public policy initiatives are considered within each of these separate...

  15. Stabilizing Sustainability

    DEFF Research Database (Denmark)

    Reitan Andersen, Kirsti

    The publication of the Brundtland Report in 1987 put the topic of sustainable development on the political and corporate agenda. Defining sustainable development as “a development that meets the needs of the future without compromising the ability of future generations to meet their own needs......” (WCED, 1987, p. 43), the Report also put a positive spin on the issue of sustainability by upholding capitalist beliefs in the possibility of infinite growth in a world of finite resources. While growth has delivered benefits, however, it has done so unequally and unsustainably. This thesis focuses...... on the textile and fashion industry, one of the world’s most polluting industries and an industry to some degree notorious for leading the ‘race to the bottom’ in global labour standards. Despite being faced with increasing demands to practise sustainability, most textile and fashion companies continue to fail...

  16. Sustainability reporting

    NARCIS (Netherlands)

    Kolk, A.

    2005-01-01

    This article gives an overview of developments in sustainability (also sometimes labelled corporate social responsibility) reporting. The article will first briefly indicate how accountability on social and environmental issues started, already in the 1970s when social reports were published.

  17. Sustainable Cities

    DEFF Research Database (Denmark)

    Georg, Susse; Garza de Linde, Gabriela Lucía

    Judging from the number of communities and cities striving or claiming to be sustainable and how often eco-development is invoked as the means for urban regeneration, it appears that sustainable and eco-development have become “the leading paradigm within urban development” (Whitehead 2003......), urban design competitions are understudied mechanisms for bringing about field level changes. Drawing on actor network theory, this paper examines how urban design competitions may bring about changes within the professional field through the use of intermediaries such as a sustainable planning....../assessment tool. The context for our study is urban regeneration in one Danish city, which had been suffering from industrial decline and which is currently investing in establishing a “sustainable city”. Based on this case study we explore how the insights and inspiration evoked in working with the tool...

  18. Sustainable responsibilities?

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    2015-01-01

    This working paper analyzes the conceptions of corporate responsibility for sustainable development in EU policies on CSR. The notion of corporate responsibility has until recently been limited to economical and legal responsibilities. Based on this narrow conception of corporate responsibility.......e. a combination of destruction and construction, this chapter will deconstruct conceptions of responsibility for sustainable development in these EU documents on CSR. A deconstructive conceptual analysis involves destructing dominant interpretations of a text and allowing for constructions of alternative...... such as sustainability actually means, but on what the concept says and does not say. A deconstructive analysis of EU policies on CSR, then, pinpoints that such policies are sites of conceptual struggles. This kind of analysis is suitable for studying conceptions of corporate responsibility for sustainable development...

  19. Agriculture: Sustainability

    Science.gov (United States)

    Sustainability creates and maintains the conditions under which humans and nature can exist in productive harmony, that permit fulfilling the food, feed, and fiber needs of our country and the social, economic and other requirements.

  20. [Why proton therapy? And how?

    Science.gov (United States)

    Thariat, Juliette; Habrand, Jean Louis; Lesueur, Paul; Chaikh, Abdulhamid; Kammerer, Emmanuel; Lecomte, Delphine; Batalla, Alain; Balosso, Jacques; Tessonnier, Thomas

    2018-02-05

    Proton therapy is a radiotherapy, based on the use of protons, charged subatomic particles that stop at a given depth depending on their initial energy (pristine Bragg peak), avoiding any output beam, unlike the photons used in most of the other modalities of radiotherapy. Proton therapy has been used for 60 years, but has only become ubiquitous in the last decade because of recent major advances in particle accelerator technology. This article reviews the history of clinical implementation of protons, the nature of the technological advances that now allows its expansion at a lower cost. It also addresses the technical and physical specificities of proton therapy and the clinical situations for which proton therapy may be relevant but requires evidence. Different proton therapy techniques are possible. These are explained in terms of their clinical potential by explaining the current terminology (such as cyclotrons, synchrotrons or synchrocyclotrons, using superconducting magnets, fixed line or arm rotary with passive diffusion delivery or active by scanning) in basic words. The requirements associated with proton therapy are increased due to the precision of the depth dose deposit. The learning curve of proton therapy requires that clinical indications be prioritized according to their associated uncertainties (such as range uncertainties and movement in lung tumors). Many clinical indications potentially fall under proton therapy ultimately. Clinical strategies are explained in a paralleled manuscript. Copyright © 2018 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  1. Sustainable, Reliable Mission-Systems Architecture

    Science.gov (United States)

    O'Neil, Graham; Orr, James K.; Watson, Steve

    2007-01-01

    A mission-systems architecture, based on a highly modular infrastructure utilizing: open-standards hardware and software interfaces as the enabling technology is essential for affordable and sustainable space exploration programs. This mission-systems architecture requires (a) robust communication between heterogeneous system, (b) high reliability, (c) minimal mission-to-mission reconfiguration, (d) affordable development, system integration, and verification of systems, and (e) minimal sustaining engineering. This paper proposes such an architecture. Lessons learned from the Space Shuttle program and Earthbound complex engineered system are applied to define the model. Technology projections reaching out 5 years are mde to refine model details.

  2. Sustainable finance

    OpenAIRE

    Boersma-de Jong, Margreet F.

    2012-01-01

    Presentation for Springschool of Strategy, University of Groningen, 10 October 2012. The role of CSR is to stimulate ethical behaviour, and as a result, mutual trust in society. Advantage of CSR for the company and the evolution of CSR. From CSR to Sustainable Finance: how does CSR influence Sustainable Business Administration & Management Accounting, Financial Leadership and what is the importance of CSR in the financial sector

  3. Proton Radiography Imager:Generates Synthetic Proton Radiographs

    Energy Technology Data Exchange (ETDEWEB)

    2017-09-12

    ProRad is a computer program that is used to generate synthetic images of proton (or other charged particles) radiographs. The proton radiographs arc images that arc obtained by sending energetic protons (or electrons or positrons, for example) through 11 plasma where electric and/or magnetic fields alter the particles trajectory, Dnd the variations me imaged on RC film, image plate, or equivalent

  4. SUSTAINABLE TRANSPORTATION

    Directory of Open Access Journals (Sweden)

    Linda STEG

    2007-01-01

    Full Text Available This paper discusses possible contributions of psychologists to sustainable transportation. It is argued that in order to reach sustainable transportation, among others, behaviour changes of individual car users are needed. As transport policies will be more effective if they target important antecedents of travel behaviour, first, factors influencing such behaviour are discussed. It is argued that car use is very attractive and sometimes even necessary for many different reasons. This implies that a combination of policies is called for, each targeting different factors that support car use and hinder the use of more sustainable modes of transport. Next, the paper elaborates on policy strategies that may be employed to achieve sustainable transportation by changing car use. Increasing the attractiveness of sustainable transport modes by means of pull measures seems not sufficient to reduce the level of car use. Besides, car use should be made less attractive by means of push measures to force drivers to reconsider their travel behaviour. The acceptability of such policies may be increased by clearly communicating the aim of these policies, and the expected positive consequences (e.g., less congestion, improved environmental quality. Moreover, possible negative effects for individual freedom may be compensated by implementing additional policies aimed at facilitating the use of sustainable transport modes.

  5. Sustainable markets for sustainable energy

    Energy Technology Data Exchange (ETDEWEB)

    Millan, J.; Smyser, C.

    1997-12-01

    The author discusses how the Inter-American Development Bank (IDB) is involved in sustainable energy development. It presently has 50 loans and grants for non conventional renewable energy projects and ten grants for efficiency programs for $600 and $17 million respectively, representing 100 MW of power. The IDB is concerned with how to create a sustainable market for sustainable energy projects. The IDB is trying to work with government, private sector, NGOs, trading allies, credit sources, and regulators to find proper roles for such projects. He discusses how the IDB is working to expand its vision and objectives in renewable energy projects in Central and South America.

  6. Differential Cross Sections for Proton-Proton Elastic Scattering

    Science.gov (United States)

    Norman, Ryan B.; Dick, Frank; Norbury, John W.; Blattnig, Steve R.

    2009-01-01

    Proton-proton elastic scattering is investigated within the framework of the one pion exchange model in an attempt to model nucleon-nucleon interactions spanning the large range of energies important to cosmic ray shielding. A quantum field theoretic calculation is used to compute both differential and total cross sections. A scalar theory is then presented and compared to the one pion exchange model. The theoretical cross sections are compared to proton-proton scattering data to determine the validity of the models.

  7. Thermal protection optimization for the space shuttle.

    Science.gov (United States)

    Garcia, F., Jr.; Fowler, W. T.

    1972-01-01

    This paper discusses optimal entry trajectories for the space shuttle that minimize the weight of an entry thermal protection system. The analysis was made using mathematical models of two types of thermal protection systems that were under consideration for the space shuttle: a metallic thermal protection system, and a reusable surface insulation thermal protection system. Optimal entries were generated using maximum orbiter nose temperature as a parameter. Thermal protection system weights were computed for both fixed and variable angles of attack using three-dimensional entry trajectories. Results indicated that variable angle-of-attack entries require less thermal protection system weight than entries at a constant angle of attack (35 deg) for both systems considered. Results also showed that 95 to 99 per cent of the thermal protection system weight requirement resulted from flight regimes in which the flow was still laminar.

  8. STS-76 liftoff - aft end of shuttle

    Science.gov (United States)

    1996-01-01

    The chase to catch up with the Russian Space Station Mir gets under way with an on-time liftoff, as the Space Shuttle Atlantis hurtles skyward from Launch Pad 39B at 3:13:04 a.m. EST, March 22. On board for Mission STS-76 -- also the 76th Shuttle flight - - are a crew of six: Mission Commander Kevin P. Chilton; Pilot Richard A. Searfoss; Payload Commander Ronald M. Sega; and Mission Specialists Michael Richard 'Rich' Clifford, Linda M. Godwin, and Shannon W. Lucid. During the course of the planned nine-day flight, Atlantis will rendezvous and dock with Mir for athe third time. Lucid will transfer to the station for an approximately four-and-a-half month stay, becoming the first American woman to live on Mir. In addition, Godwin and Clifford will perform an extravehicular activity later in the mission, the first around the mated Atlantis-Mir assembly.

  9. Shuttle Earth Views, 1994. Part 3

    Science.gov (United States)

    1995-01-01

    In this third part of a four-part video compilation of Space Shuttle Earth views, various geographical areas are shown, including both land and water masses. The views cover South America, Asia (North Vietnam, Laos, Cambodia, China, Malaysia, Thailand, Java, various islands, Burma, Philippines, Taiwan, Guam), New Guinea, Australia, Morocco, Southern Europe (Spain, Portugal, Algeria, Italy, Sicily, Greece, Former Republic of Yugoslavia, Tunisia), and parts of the Middle East (Libya, Saudi Arabia, Egypt, Israel, Jordan, Sinai, Cyprus, Lebanon, Iraq), the Pacific Ocean, the Atlantic Ocean, the Indian Ocean, and the Mediterranean, Dead, Coral, Tyrrhenian, Adriatic, Ionian, Red, South China, Mindanao, Arafura, Sulu, Java, and China Seas. Each film clip has a heading that names the shuttle and the geographical location of the footage.

  10. A VLF transmitter on the Space Shuttle

    Science.gov (United States)

    Inan, U. S.; Bell, T. F.; Helliwell, R. A.; Katsufrakis, K. P.

    The use of space-borne transmitters for the study of interactions of energetic radiation belt particles and coherent plasma waves in the earth's magnetosphere has been considered. The proposed Space Shuttle/Space Lab system would provide a useful VLF transmitter platform since it can lift the required large payloads into orbit, erect long antennas, supply the electrical power required, and provide real-time control. A study is conducted of the power budget of such a VLF transmitter in an attempt to assess the feasibility of the experiment. It is found that a 1-10 kW transmitter placed on the Space Shuttle/Space Lab system can inject from one watt to up to a few kilowatts of wave power into the whistler mode. Recent results of ground-based VLF wave-injection experiments show that such power levels would be more than enough for initiating nonlinear wave growth and amplification and emission triggering in the magnetosphere.

  11. Shuttle Kit Freezer Refrigeration Unit Conceptual Design

    Science.gov (United States)

    Copeland, R. J.

    1975-01-01

    The refrigerated food/medical sample storage compartment as a kit to the space shuttle orbiter is examined. To maintain the -10 F in the freezer kit, an active refrigeration unit is required, and an air cooled Stirling Cycle refrigerator was selected. The freezer kit contains two subsystems, the refrigeration unit, and the storage volume. The freezer must provide two basic capabilities in one unit. One requirement is to store 215 lbs of food which is consumed in a 30-day period by 7 people. The other requirement is to store 128.3 lbs of medical samples consisting of both urine and feces. The unit can be mounted on the lower deck of the shuttle cabin, and will occupy four standard payload module compartments on the forward bulkhead. The freezer contains four storage compartments.

  12. Space Shuttle security policies and programs

    Science.gov (United States)

    Keith, E. L.

    1985-01-01

    The Space Shuttle vehicle consists of the orbiter, external tank, and two solid rocket boosters. In dealing with security two major protective categories are considered, taking into account resource protection and information protection. A review is provided of four basic programs which have to be satisfied. Aspects of science and technology transfer are discussed. The restrictions for the transfer of science and technology information are covered under various NASA Management Instructions (NMI's). There were two major events which influenced the protection of sensitive and private information on the Space Shuttle program. The first event was a manned space flight accident, while the second was the enactment of a congressional bill to establish the rights of privacy. Attention is also given to national resource protection and national defense classified operations.

  13. Optimal Wafer Cutting in Shuttle Layout Problems

    DEFF Research Database (Denmark)

    Nisted, Lasse; Pisinger, David; Altman, Avri

    2011-01-01

    . The shuttle layout problem is frequently solved in two phases: first, a floorplan of the shuttle is generated. Then, a cutting plan is found which minimizes the overall number of wafers needed to satisfy the demand of each die type. Since some die types require special production technologies, only compatible...... dies can be cut from a given wafer, and each cutting plan must respect various constraints on where the cuts may be placed. We present an exact algorithm for solving the minimum cutting plan problem, given a floorplan of the dies. The algorithm is based on delayed column generation, where the pricing...... problem becomes a maximum vertex-weighted clique problem in which each clique consists of cutting compatible dies. The resulting branch-and-price algorithm is able to solve realistic cutting problems to optimality in a couple of seconds....

  14. Measurement of small-angle antiproton-proton and proton-proton elastic scattering at the CERN intersecting storage rings

    NARCIS (Netherlands)

    Amos, N.; Block, M.M.; Bobbink, G.J.; Botje, M.A.J.; Favart, D.; Leroy, C.; Linde, F.; Lipnik, P.; Matheys, J-P.; Miller, D.

    1985-01-01

    Antiproton-proton and proton-proton small-angle elastic scattering was measured for centre-of-mass energies at the CERN Intersectung Storage Rings. In addition, proton-proton elastic scattering was measured at . Using the optical theorem, total cross sections are obtained with an accuracy of about

  15. Conjugate gradient optimization programs for shuttle reentry

    Science.gov (United States)

    Powers, W. F.; Jacobson, R. A.; Leonard, D. A.

    1972-01-01

    Two computer programs for shuttle reentry trajectory optimization are listed and described. Both programs use the conjugate gradient method as the optimization procedure. The Phase 1 Program is developed in cartesian coordinates for a rotating spherical earth, and crossrange, downrange, maximum deceleration, total heating, and terminal speed, altitude, and flight path angle are included in the performance index. The programs make extensive use of subroutines so that they may be easily adapted to other atmospheric trajectory optimization problems.

  16. Shuttle Engine Designs Revolutionize Solar Power

    Science.gov (United States)

    2014-01-01

    The Space Shuttle Main Engine was built under contract to Marshall Space Flight Center by Rocketdyne, now part of Pratt & Whitney Rocketdyne (PWR). PWR applied its NASA experience to solar power technology and licensed the technology to Santa Monica, California-based SolarReserve. The company now develops concentrating solar power projects, including a plant in Nevada that has created 4,300 jobs during construction.

  17. Physics controversies in proton therapy.

    Science.gov (United States)

    Engelsman, Martijn; Schwarz, Marco; Dong, Lei

    2013-04-01

    The physical characteristics of proton beams are appealing for cancer therapy. The rapid increase in operational and planned proton therapy facilities may suggest that this technology is a "plug-and-play" valuable addition to the arsenal of the radiation oncologist and medical physicist. In reality, the technology is still evolving, so planning and delivery of proton therapy in patients face many practical challenges. This review article discusses the current status of proton therapy treatment planning and delivery techniques, indicates current limitations in dealing with range uncertainties, and proposes possible developments for proton therapy and supplementary technology to try to realize the actual potential of proton therapy. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Proton and carbon ion therapy

    CERN Document Server

    Lomax, Tony

    2013-01-01

    Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art...

  19. Proton Upset Monte Carlo Simulation

    Science.gov (United States)

    O'Neill, Patrick M.; Kouba, Coy K.; Foster, Charles C.

    2009-01-01

    The Proton Upset Monte Carlo Simulation (PROPSET) program calculates the frequency of on-orbit upsets in computer chips (for given orbits such as Low Earth Orbit, Lunar Orbit, and the like) from proton bombardment based on the results of heavy ion testing alone. The software simulates the bombardment of modern microelectronic components (computer chips) with high-energy (.200 MeV) protons. The nuclear interaction of the proton with the silicon of the chip is modeled and nuclear fragments from this interaction are tracked using Monte Carlo techniques to produce statistically accurate predictions.

  20. Microbiological Lessons Learned from the Space Shuttle

    Science.gov (United States)

    Pierson, Duane L.; Ott, C. Mark; Bruce, Rebekah; Castro, Victoria A.; Mehta, Satish K.

    2011-01-01

    After 30 years of being the centerpiece of NASA s human spacecraft, the Space Shuttle will retire. This highly successful program provided many valuable lessons for the International Space Station (ISS) and future spacecraft. Major microbiological risks to crewmembers include food, water, air, surfaces, payloads, animals, other crewmembers, and ground support personnel. Adverse effects of microorganisms are varied and can jeopardize crew health and safety, spacecraft systems, and mission objectives. Engineering practices and operational procedures can minimize the negative effects of microorganisms. To minimize problems associated with microorganisms, appropriate steps must begin in the design phase of new spacecraft or space habitats. Spacecraft design must include requirements to control accumulation of water including humidity, leaks, and condensate on surfaces. Materials used in habitable volumes must not contribute to microbial growth. Use of appropriate materials and the implementation of robust housekeeping that utilizes periodic cleaning and disinfection will prevent high levels of microbial growth on surfaces. Air filtration can ensure low levels of bioaerosols and particulates in the breathing air. The use of physical and chemical steps to disinfect drinking water coupled with filtration can provide safe drinking water. Thorough preflight examination of flight crews, consumables, and the environment can greatly reduce pathogens in spacecraft. The advances in knowledge of living and working onboard the Space Shuttle formed the foundation for environmental microbiology requirements and operations for the International Space Station (ISS) and future spacecraft. Research conducted during the Space Shuttle Program resulted in an improved understanding of the effects of spaceflight on human physiology, microbial properties, and specifically the host-microbe interactions. Host-microbe interactions are substantially affected by spaceflight. Astronaut immune

  1. Shuttle Topography Data Inform Solar Power Analysis

    Science.gov (United States)

    2013-01-01

    The next time you flip on a light switch, there s a chance that you could be benefitting from data originally acquired during the Space Shuttle Program. An effort spearheaded by Jet Propulsion Laboratory (JPL) and the National Geospatial-Intelligence Agency (NGA) in 2000 put together the first near-global elevation map of the Earth ever assembled, which has found use in everything from 3D terrain maps to models that inform solar power production. For the project, called the Shuttle Radar Topography Mission (SRTM), engineers at JPL designed a 60-meter mast that was fitted onto Shuttle Endeavour. Once deployed in space, an antenna attached to the end of the mast worked in combination with another antenna on the shuttle to simultaneously collect data from two perspectives. Just as having two eyes makes depth perception possible, the SRTM data sets could be combined to form an accurate picture of the Earth s surface elevations, the first hight-detail, near-global elevation map ever assembled. What made SRTM unique was not just its surface mapping capabilities but the completeness of the data it acquired. Over the course of 11 days, the shuttle orbited the Earth nearly 180 times, covering everything between the 60deg north and 54deg south latitudes, or roughly 80 percent of the world s total landmass. Of that targeted land area, 95 percent was mapped at least twice, and 24 percent was mapped at least four times. Following several years of processing, NASA released the data to the public in partnership with NGA. Robert Crippen, a member of the SRTM science team, says that the data have proven useful in a variety of fields. "Satellites have produced vast amounts of remote sensing data, which over the years have been mostly two-dimensional. But the Earth s surface is three-dimensional. Detailed topographic data give us the means to visualize and analyze remote sensing data in their natural three-dimensional structure, facilitating a greater understanding of the features

  2. Roundtabling Sustainability

    DEFF Research Database (Denmark)

    Ponte, Stefano

    2014-01-01

    The willingness of public authority to delegate social and environmental regulation to the private sector has varied from sector to sector, but has often led to the establishment of ‘voluntary’ standards and certifications on sustainability. Many of these have taken the form of ‘stewardship...... councils’ and ‘sustainability roundtables’ and have been designed around a set of institutional features seeking to establish legitimacy, fend off possible criticism, and ‘sell’ certifications to potential users. The concept of ‘roundtabling’ emphasizes the fitting a variety of commodity......-specific sustainability situations into a form that not only ‘hears more voices’ (as in ‘multi-stakeholder’), but also portrays to give them equal standing at the table of negotiations (roundtable), thus raising higher expectations on accountability, transparency and inclusiveness. In this article, I examine to what...

  3. Vibrational spectroscopy on protons and deuterons in proton conducting perovskites

    DEFF Research Database (Denmark)

    Glerup, M.; Poulsen, F.W.; Berg, R.W.

    2002-01-01

    A short review of IR-spectroscopy on protons in perovskite structure oxides is given. The nature of possible proton sites, libration and combination tones and degree of hydrogen bonding is emphasised. Three new spectroscopic experiments and/or interpretations are presented. An IR-microscopy exper...

  4. Effects of relativity in proton-proton bremsstrahlung

    NARCIS (Netherlands)

    Martinus, G.H.; Scholten, O.; Tjon, J.A.

    1997-01-01

    We investigate the influence of negative-energy states in proton-proton bremsstrahlung in a fully relativistic framework using the T matrix of Fleischer and Tjon. The contribution from negative-energy states in the single-scattering diagrams is shown to be large, indicating that relativistic effects

  5. Proton-proton virtual bremsstrahlung in a relativistic covariant model

    NARCIS (Netherlands)

    Martinus, GH; Scholten, O; Tjon, J

    1999-01-01

    Lepton-pair production (virtual bremsstrahlung) in proton-proton scattering is investigated using a relativistic covariant model. The effects of negative-energy slates and two-body currents are studied. These are shown to have large effects in some particular structure functions, even at the

  6. Electromagnetic off-shell effects in proton-proton bremsstrahlung

    NARCIS (Netherlands)

    Kondratyuk, S.A.; Martinus, G.H.; Scholten, O.

    1998-01-01

    We study the influence of the off-shell structure of the nucleon electromagnetic vertex on proton-proton bermsstrahlung observables. Realistic choices for the off-shell behavior are found to have considerable influences on observables such as cross sections and analyzing powers. The rescattering

  7. [Proton imaging applications for proton therapy: state of the art].

    Science.gov (United States)

    Amblard, R; Floquet, V; Angellier, G; Hannoun-Lévi, J M; Hérault, J

    2015-04-01

    Proton therapy allows a highly precise tumour volume irradiation with a low dose delivered to the healthy tissues. The steep dose gradients observed and the high treatment conformity require a precise knowledge of the proton range in matter and the target volume position relative to the beam. Thus, proton imaging allows an improvement of the treatment accuracy, and thereby, in treatment quality. Initially suggested in 1963, radiographic imaging with proton is still not used in clinical routine. The principal difficulty is the lack of spatial resolution, induced by the multiple Coulomb scattering of protons with nuclei. Moreover, its realization for all clinical locations requires relatively high energies that are previously not considered for clinical routine. Abandoned for some time in favor of X-ray technologies, research into new imaging methods using protons is back in the news because of the increase of proton radiation therapy centers in the world. This article exhibits a non-exhaustive state of the art in proton imaging. Copyright © 2015 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

  8. Slope analysis for elastic proton-proton and proton-antiproton scattering

    OpenAIRE

    Okorokov, V. A.

    2008-01-01

    The diffraction slope parameter is investigated for elastic proton-proton and proton-antiproton scattering based on the all available experimental data at intermediate square of momentum transfer in the main. Energy dependence of the elastic diffraction slope is approximated by various analytic functions in a model-independent fashion. The expanded standard logarithmic approximations allow to describe experimental slopes in all available energy range at qualitative level reasonably. Various f...

  9. Sustainability Evaluation.

    Science.gov (United States)

    Stichnothe, Heinz

    2017-03-17

    The long-term substitution of fossil resources can only be achieved through a bio-based economy, with biorefineries and bio-based products playing a major role. However, it is important to assess the implications of the transition to a bio-based economy. Life cycle-based sustainability assessment is probably the most suitable approach to quantify impacts and to identify trade-offs at multiple levels. The extended utilisation of biomass can cause land use change and affect food security of the most vulnerable people throughout the world. Although this is mainly a political issue and governments should be responsible, the responsibility is shifted to companies producing biofuels and other bio-based products. Organic wastes and lignocellulosic biomass are considered to be the preferred feedstock for the production of bio-based products. However, it is unlikely that a bio-based economy can rely only on organic wastes and lignocellulosic biomass.It is crucial to identify potential problems related to socio-economic and environmental issues. Currently there are many approaches to the sustainability of bio-based products, both quantitative and qualitative. However, results of different calculation methods are not necessarily comparable and can cause confusion among decision-makers, stakeholders and the public.Hence, a harmonised, globally agreed approach would be the best solution to secure sustainable biomass/biofuels/bio-based chemicals production and trade, and to avoid indirect effects (e.g. indirect land use change). However, there is still a long way to go.Generally, the selection of suitable indicators that serve the purpose of sustainability assessment is very context-specific. Therefore, it is recommended to use a flexible and modular approach that can be adapted to various purposes. A conceptual model for the selection of sustainability indicators is provided that facilitates identifying suitable sustainability indicators based on relevance and significance in a

  10. CERN Shuttles - NEW Regular Shuttle Services as from 11/01/2010

    CERN Multimedia

    GS Department

    2010-01-01

    As of Monday 11 January a new regular shuttle service (from Monday to Friday) will be available to facilitate transportation: Within and between both CERN sites, Meyrin and Prevessin; To and from the following LHC points: ATLAS, ALICE, CMS, LHCb. For further details, please consult the timetable for this service. We should also like to take this opportunity to encourage you to use the new regular TPG Y bus service rather than the special on-demand CERN transport service to and from Geneva Airport whenever possible. The TPG buses run from 06:00 to 00:30. For further details, please consult the TPG timetable. Please do not hesitate to give us your feedback on the shuttle services: e-mail to veronique.marchal@cern.ch. In case of problems with the shuttles, please contact 75411. GS-SEM Group Infrastructure and General Services Department

  11. Transverse spin effects in proton-proton scattering and $Q \\bar Q$ production

    OpenAIRE

    Goloskokov, S. V.

    2002-01-01

    We discuss transverse spin effects caused by the spin-flip part of the Pomeron coupling with the proton. The predicted spin asymmetries in proton-proton scattering and QQ production in proton-proton and lepton-proton reactions are not small and can be studied in future polarized experiments.

  12. Proton minibeam radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Girst, Stefanie

    2016-03-08

    The risk of developing adverse side effects in the normal tissue after radiotherapy is often limiting for the dose that can be applied to the tumor. Proton minibeam radiotherapy, a spatially fractionated radiotherapy method using sub-millimeter proton beams, similar to grid therapy or microbeam radiation radiotherapy (MRT) using X-rays, has recently been invented at the ion microprobe SNAKE in Munich. The aim of this new concept is to minimize normal tissue injuries in the entrance channel and especially in the skin by irradiating only a small percentage of the cells in the total irradiation field, while maintaining tumor control via a homogeneous dose in the tumor, just like in conventional broad beam radiotherapy. This can be achieved by optimizing minibeam sizes and distances according to the prevailing tumor size and depth such that after widening of the minibeams due to proton interactions in the tissue, the overlapping minibeams produce a homogeneous dose distribution throughout the tumor. The aim of this work was to elucidate the prospects of minibeam radiation therapy compared to conventional homogeneous broad beam radiotherapy in theory and in experimental studies at the ion microprobe SNAKE. Treatment plans for model tumors of different sizes and depths were created using the planning software LAPCERR, to elaborate suitable minibeam sizes and distances for the individual tumors. Radiotherapy-relevant inter-beam distances required to obtain a homogeneous dose in the target volume were found to be in the millimeter range. First experiments using proton minibeams of only 10 μm and 50 μm size (termed microchannels in the corresponding publication Zlobinskaya et al. 2013) and therapy-conform larger dimensions of 100 μm and 180 μm were performed in the artificial human in-vitro skin model EpiDermFT trademark (MatTek). The corresponding inter-beam distances were 500 μm, 1mm and 1.8 mm, respectively, leading to irradiation of only a few percent of the cells

  13. Proton transport in carbonic anhydrase: Insights from molecular simulation.

    Science.gov (United States)

    Maupin, C Mark; Voth, Gregory A

    2010-02-01

    This article reviews the insights gained from molecular simulations of human carbonic anhydrase II (HCA II) utilizing non-reactive and reactive force fields. The simulations with a reactive force field explore protein transfer and transport via Grotthuss shuttling, while the non-reactive simulations probe the larger conformational dynamics that underpin the various contributions to the rate-limiting proton transfer event. Specific attention is given to the orientational stability of the His64 group and the characteristics of the active site water cluster, in an effort to determine both of their impact on the maximal catalytic rate. The explicit proton transfer and transport events are described by the multistate empirical valence bond (MS-EVB) method, as are alternative pathways for the excess proton charge defect to enter/leave the active site. The simulation results are interpreted in light of experimental results on the wild-type enzyme and various site-specific mutations of HCA II in order to better elucidate the key factors that contribute to its exceptional efficiency. Copyright 2009 Elsevier B.V. All rights reserved.

  14. [FeFe]hydrogenase mimics for proton reduction catalysis: Supramolecular proton reduction catalysts with appended redox-active and proton-responsive ligands towards application in a molecular artificial leaf

    OpenAIRE

    Becker, R

    2016-01-01

    Hydrogen gas is a viable, sustainable alternative to fossil fuels, but only when produced from sustainable resources such as water and sunlight. Devices that can perform the photocatalytic splitting of water are colloquially called ‘artificial leaves’ and should contain at least a light-absorbing entity and water splitting catalysts. In this thesis, molecular catalysts are studied that mimic the all-iron hydrogenase enzyme which can convert electrons and protons into dihydrogen. Two main func...

  15. Proton therapy - Present and future.

    Science.gov (United States)

    Mohan, Radhe; Grosshans, David

    2017-01-15

    In principle, proton therapy offers a substantial clinical advantage over conventional photon therapy. This is because of the unique depth-dose characteristics of protons, which can be exploited to achieve significant reductions in normal tissue doses proximal and distal to the target volume. These may, in turn, allow escalation of tumor doses and greater sparing of normal tissues, thus potentially improving local control and survival while at the same time reducing toxicity and improving quality of life. Protons, accelerated to therapeutic energies ranging from 70 to 250MeV, typically with a cyclotron or a synchrotron, are transported to the treatment room where they enter the treatment head mounted on a rotating gantry. The initial thin beams of protons are spread laterally and longitudinally and shaped appropriately to deliver treatments. Spreading and shaping can be achieved by electro-mechanical means to treat the patients with "passively-scattered proton therapy" (PSPT) or using magnetic scanning of thin "beamlets" of protons of a sequence of initial energies. The latter technique can be used to treat patients with optimized intensity modulated proton therapy (IMPT), the most powerful proton modality. Despite the high potential of proton therapy, the clinical evidence supporting the broad use of protons is mixed. It is generally acknowledged that proton therapy is safe, effective and recommended for many types of pediatric cancers, ocular melanomas, chordomas and chondrosarcomas. Although promising results have been and continue to be reported for many other types of cancers, they are based on small studies. Considering the high cost of establishing and operating proton therapy centers, questions have been raised about their cost effectiveness. General consensus is that there is a need to conduct randomized trials and/or collect outcomes data in multi-institutional registries to unequivocally demonstrate the advantage of protons. Treatment planning and plan

  16. Sustainable Soesterkwartier

    NARCIS (Netherlands)

    Abrahams, H.; Goosen, H.; Jong, de F.; Sickmann, J.; Prins, D.

    2010-01-01

    The municipality of Amersfoort wants to construct an endurable and sustainable eco-town in the Soesterkwartier neighbourhood, by taking future climate change into account. The impact of climate change at the location of the proposed eco-town was studied by a literature review.

  17. Sustainable agriculture

    International Development Research Centre (IDRC) Digital Library (Canada)

    New farming techniques, better food security. Since 1970, IDRC-supported research has introduced sustainable agricultural practices to farmers and communities across the devel- oping world. The result: higher productivity, less poverty, greater food security, and a healthier environment. Opportunities grow on trees in ...

  18. Sustainable Development

    African Journals Online (AJOL)

    Tsegai Berhane Ghebretekle

    Abstract. This article examines the concept of sustainable development after the Post-. 2015 Paris Climate Change Agreement with particular emphasis on Ethiopia. Various African countries are vulnerable to climate change, as is evidenced by recent droughts. Ethiopia is selected as a case study in light of its pace in.

  19. Sustainable machining

    CERN Document Server

    2017-01-01

    This book provides an overview on current sustainable machining. Its chapters cover the concept in economic, social and environmental dimensions. It provides the reader with proper ways to handle several pollutants produced during the machining process. The book is useful on both undergraduate and postgraduate levels and it is of interest to all those working with manufacturing and machining technology.

  20. Architecture Sustainability

    NARCIS (Netherlands)

    Avgeriou, Paris; Stal, Michael; Hilliard, Rich

    2013-01-01

    Software architecture is the foundation of software system development, encompassing a system's architects' and stakeholders' strategic decisions. A special issue of IEEE Software is intended to raise awareness of architecture sustainability issues and increase interest and work in the area. The

  1. Sustainability reporting

    NARCIS (Netherlands)

    Kolk, A.

    2005-01-01

    This article gives an overview of developments in sustainability (also sometimes labelled corporate social responsibility) reporting. It The article will first briefly indicate how accountability on social and environmental issues started, already in the 1970s when social reports were published.

  2. Exergy sustainability.

    Energy Technology Data Exchange (ETDEWEB)

    Robinett, Rush D. III (.; ); Wilson, David Gerald; Reed, Alfred W.

    2006-05-01

    Exergy is the elixir of life. Exergy is that portion of energy available to do work. Elixir is defined as a substance held capable of prolonging life indefinitely, which implies sustainability of life. In terms of mathematics and engineering, exergy sustainability is defined as the continuous compensation of irreversible entropy production in an open system with an impedance and capacity-matched persistent exergy source. Irreversible and nonequilibrium thermodynamic concepts are combined with self-organizing systems theories as well as nonlinear control and stability analyses to explain this definition. In particular, this paper provides a missing link in the analysis of self-organizing systems: a tie between irreversible thermodynamics and Hamiltonian systems. As a result of this work, the concept of ''on the edge of chaos'' is formulated as a set of necessary and sufficient conditions for stability and performance of sustainable systems. This interplay between exergy rate and irreversible entropy production rate can be described as Yin and Yang control: the dialectic synthesis of opposing power flows. In addition, exergy is shown to be a fundamental driver and necessary input for sustainable systems, since exergy input in the form of power is a single point of failure for self-organizing, adaptable systems.

  3. Sustainable processing

    DEFF Research Database (Denmark)

    Kristensen, Niels Heine

    2004-01-01

    Kristensen_NH and_Beck A: Sustainable processing. In Otto Schmid, Alexander Beck and Ursula Kretzschmar (Editors) (2004): Underlying Principles in Organic and "Low-Input Food" Processing - Literature Survey. Research Institute of Organic Agriculture FiBL, CH-5070 Frick, Switzerland. ISBN 3-906081-58-3...

  4. Sustainable finance

    NARCIS (Netherlands)

    dr. Margreet F. Boersma-de Jong

    2012-01-01

    Presentation for Springschool of Strategy, University of Groningen, 10 October 2012. The role of CSR is to stimulate ethical behaviour, and as a result, mutual trust in society. Advantage of CSR for the company and the evolution of CSR. From CSR to Sustainable Finance: how does CSR influence

  5. Transgenerational effects of proton beam irradiation on Caenorhabditis elegans germline apoptosis.

    Science.gov (United States)

    Min, Hyemin; Sung, Minhee; Son, Miseol; Kawasaki, Ichiro; Shim, Yhong-Hee

    2017-08-26

    When treating cancer using radiation therapy, it is critical to increase patient survival rates and to reduce side effects. In this respect, proton beam radiation treatment performs better than other radiation treatments because of its high target specificity. However, complications still remain after proton beam radiation treatment. Among them, the risk to progeny after irradiation of their parents is a major concern. In this study, we analyzed the transgenerational effects of proton beam irradiation using the model organism Caenorhabditis. elegans. We found that germline apoptosis increased after proton beam irradiation and its effects were sustained transgenerationally. Moreover, we identified that a germline-specific histone methyltransferase component, SET-2, has a critical role in transmitting the transgenerational effect on germline apoptosis to the next generation after proton beam irradiation. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Teledyne Energy Systems, Inc., Proton Exchange Member (PEM) Fuel Cell Engineering Model Powerplant. Test Report: Initial Benchmark Tests in the Original Orientation

    Science.gov (United States)

    Loyselle, Patricia; Prokopius, Kevin

    2011-01-01

    Proton Exchange Membrane (PEM) fuel cell technology is the leading candidate to replace the alkaline fuel cell technology, currently used on the Shuttle, for future space missions. During a 5-yr development program, a PEM fuel cell powerplant was developed. This report details the initial performance evaluation test results of the powerplant.

  7. Nanotechnology for environmentally sustainable electromobility

    Science.gov (United States)

    Ellingsen, Linda Ager-Wick; Hung, Christine Roxanne; Majeau-Bettez, Guillaume; Singh, Bhawna; Chen, Zhongwei; Whittingham, M. Stanley; Strømman, Anders Hammer

    2016-12-01

    Electric vehicles (EVs) powered by lithium-ion batteries (LIBs) or proton exchange membrane hydrogen fuel cells (PEMFCs) offer important potential climate change mitigation effects when combined with clean energy sources. The development of novel nanomaterials may bring about the next wave of technical improvements for LIBs and PEMFCs. If the next generation of EVs is to lead to not only reduced emissions during use but also environmentally sustainable production chains, the research on nanomaterials for LIBs and PEMFCs should be guided by a life-cycle perspective. In this Analysis, we describe an environmental life-cycle screening framework tailored to assess nanomaterials for electromobility. By applying this framework, we offer an early evaluation of the most promising nanomaterials for LIBs and PEMFCs and their potential contributions to the environmental sustainability of EV life cycles. Potential environmental trade-offs and gaps in nanomaterials research are identified to provide guidance for future nanomaterial developments for electromobility.

  8. Polarized proton collider at RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Alekseev, I.; Allgower, C.; Bai, M.; Batygin, Y.; Bozano, L.; Brown, K.; Bunce, G.; Cameron, P.; Courant, E.; Erin, S.; Escallier, J.; Fischer, W.; Gupta, R.; Hatanaka, K.; Huang, H.; Imai, K.; Ishihara, M.; Jain, A.; Lehrach, A.; Kanavets, V.; Katayama, T.; Kawaguchi, T.; Kelly, E.; Kurita, K.; Lee, S.Y.; Luccio, A.; MacKay, W.W. E-mail: mackay@bnl.govhttp://www.rhichome.bnl.gov/People/waldowaldo@bnl.gov; Mahler, G.; Makdisi, Y.; Mariam, F.; McGahern, W.; Morgan, G.; Muratore, J.; Okamura, M.; Peggs, S.; Pilat, F.; Ptitsin, V.; Ratner, L.; Roser, T.; Saito, N.; Satoh, H.; Shatunov, Y.; Spinka, H.; Syphers, M.; Tepikian, S.; Tominaka, T.; Tsoupas, N.; Underwood, D.; Vasiliev, A.; Wanderer, P.; Willen, E.; Wu, H.; Yokosawa, A.; Zelenski, A.N

    2003-03-01

    In addition to heavy ion collisions (RHIC Design Manual, Brookhaven National Laboratory), RHIC will also collide intense beams of polarized protons (I. Alekseev, et al., Design Manual Polarized Proton Collider at RHIC, Brookhaven National Laboratory, 1998, reaching transverse energies where the protons scatter as beams of polarized quarks and gluons. The study of high energy polarized protons beams has been a long term part of the program at BNL with the development of polarized beams in the Booster and AGS rings for fixed target experiments. We have extended this capability to the RHIC machine. In this paper we describe the design and methods for achieving collisions of both longitudinal and transverse polarized protons in RHIC at energies up to {radical}s=500 GeV.

  9. Polarized Proton Collisions at RHIC

    CERN Document Server

    Bai, Mei; Alekseev, Igor G; Alessi, James; Beebe-Wang, Joanne; Blaskiewicz, Michael; Bravar, Alessandro; Brennan, Joseph M; Bruno, Donald; Bunce, Gerry; Butler, John J; Cameron, Peter; Connolly, Roger; De Long, Joseph; Drees, Angelika; Fischer, Wolfram; Ganetis, George; Gardner, Chris J; Glenn, Joseph; Hayes, Thomas; Hseuh Hsiao Chaun; Huang, Haixin; Ingrassia, Peter; Iriso, Ubaldo; Laster, Jonathan S; Lee, Roger C; Luccio, Alfredo U; Luo, Yun; MacKay, William W; Makdisi, Yousef; Marr, Gregory J; Marusic, Al; McIntyre, Gary; Michnoff, Robert; Montag, Christoph; Morris, John; Nicoletti, Tony; Oddo, Peter; Oerter, Brian; Osamu, Jinnouchi; Pilat, Fulvia Caterina; Ptitsyn, Vadim; Roser, Thomas; Satogata, Todd; Smith, Kevin T; Svirida, Dima; Tepikian, Steven; Tomas, Rogelio; Trbojevic, Dejan; Tsoupas, Nicholaos; Tuozzolo, Joseph; Vetter, Kurt; Wilinski, Michelle; Zaltsman, Alex; Zelenski, Anatoli; Zeno, Keith; Zhang, S Y

    2005-01-01

    The Relativistic Heavy Ion Collider~(RHIC) provides not only collisions of ions but also collisions of polarized protons. In a circular accelerator, the polarization of polarized proton beam can be partially or fully lost when a spin depolarizing resonance is encountered. To preserve the beam polarization during acceleration, two full Siberian snakes were employed in RHIC to avoid depolarizing resonances. In 2003, polarized proton beams were accelerated to 100~GeV and collided in RHIC. Beams were brought into collisions with longitudinal polarization at the experiments STAR and PHENIX by using spin rotators. RHIC polarized proton run experience demonstrates that optimizing polarization transmission efficiency and improving luminosity performance are significant challenges. Currently, the luminosity lifetime in RHIC is limited by the beam-beam effect. The current state of RHIC polarized proton program, including its dedicated physics run in 2005 and efforts to optimize luminosity production in beam-beam limite...

  10. Redox shuttles for lithium ion batteries

    Science.gov (United States)

    Weng, Wei; Zhang, Zhengcheng; Amine, Khalil

    2014-11-04

    Compounds may have general Formula IVA or IVB. ##STR00001## where, R.sup.8, R.sup.9, R.sup.10, and R.sup.11 are each independently selected from H, F, Cl, Br, CN, NO.sub.2, alkyl, haloalkyl, and alkoxy groups; X and Y are each independently O, S, N, or P; and Z' is a linkage between X and Y. Such compounds may be used as redox shuttles in electrolytes for use in electrochemical cells, batteries and electronic devices.

  11. The first plants to fly on Shuttle

    Science.gov (United States)

    Brown, A. H.; Chapman, D. K.

    1982-01-01

    The methods and results are presented concerning experiments using the first plants to make a journey for scientific purposes in earth orbit on board Space Shuttles 2 and 3. These experiments were conducted in order to validate the culture system planned for use in a Spacelab-1 experiment involving the growth and kinetics of sunflower seedlings. The experimental flight package is described and the preparation steps taken prior to the flights are discussed. The conditions to which the plants were exposed during the flights are examined in detail, focusing on the temperature profile and the gravitational forces during reentry to landing.

  12. Shuttle payload vibroacoustic test plan evaluation

    Science.gov (United States)

    Stahle, C. V.; Gongloff, H. R.; Young, J. P.; Keegan, W. B.

    1977-01-01

    Statistical decision theory is used to evaluate seven alternate vibro-acoustic test plans for Space Shuttle payloads; test plans include component, subassembly and payload testing and combinations of component and assembly testing. The optimum test levels and the expected cost are determined for each test plan. By including all of the direct cost associated with each test plan and the probabilistic costs due to ground test and flight failures, the test plans which minimize project cost are determined. The lowest cost approach eliminates component testing and maintains flight vibration reliability by performing subassembly tests at a relatively high acoustic level.

  13. Advanced automation in space shuttle mission control

    Science.gov (United States)

    Heindel, Troy A.; Rasmussen, Arthur N.; Mcfarland, Robert Z.

    1991-01-01

    The Real Time Data System (RTDS) Project was undertaken in 1987 to introduce new concepts and technologies for advanced automation into the Mission Control Center environment at NASA's Johnson Space Center. The project's emphasis is on producing advanced near-operational prototype systems that are developed using a rapid, interactive method and are used by flight controllers during actual Shuttle missions. In most cases the prototype applications have been of such quality and utility that they have been converted to production status. A key ingredient has been an integrated team of software engineers and flight controllers working together to quickly evolve the demonstration systems.

  14. Space Shuttle Orbiter Structures and Mechanisms

    Science.gov (United States)

    Gilmore, Adam L.; Estes, Lynda R.; Eilers, James A.; Logan, Jeffrey S.; Evernden, Brent A.; Decker, William S.; Hagen, Jeffrey D.; Davis, Robert E.; Broughton, James K.; Campbell, Carlisle C.; hide

    2011-01-01

    The Space Shuttle Orbiter has performed exceptionally well over its 30 years of flight experience. Among the many factors behind this success were robust, yet carefully monitored, structural and mechanical systems. From highlighting key aspects of the design to illustrating lessons learned from the operation of this complex system, this paper will attempt to educate the reader on why some subsystems operated flawlessly and why specific vulnerabilities were exposed in others. Specific areas to be covered will be the following: high level configuration overview, primary and secondary structure, mechanical systems ranging from landing gear to the docking system, and windows.

  15. Space shuttle SRM field joint: Review paper

    OpenAIRE

    S. Mohammad Gharouni; Hamid M. Panahiha; Jafar Eskandari Jam

    2014-01-01

    Due to Challenger space shuttle accident in 1986, significant research has been done concerning structural behavior of field joints in solid rocket boosters (SRB). The structural deformations between the clevis inner leg and the tang (male-to-female parts of joint), the sealing of the O-ring to prevent the hot gas in joints, has been neglected causing the failure of the vehicle. Redesigning the field joint in SRB engine by accurate analysis of dynamic and thermal loads and by design of insula...

  16. Recent Shuttle Post Flight MMOD Inspection Highlights

    Science.gov (United States)

    Hyde, James L.; Christiansen, Eric L.; Lear, Dana M.; Herrin, Jason S.

    2010-01-01

    Four significant micro-meteoroid orbital debris (MMOD) impact events on the shuttle are documented: two perforations of the payload bay door radiator sandwich panel along with craters in a crew module window and a wing leading edge reinforced carbon-carbon panel. Results from Scanning Electron Microscope/Energy-Dispersive x-ray Spectroscopy (SEM/EDS) analysis of impact residue are provided in an attempt to identify the source of each impact. Particle sizes that could produce the observed damage are discussed, along with hypervelocity impact testing on representative samples conducted to simulate the impact event.

  17. Space Shuttle Orbiter windshield bird impact analysis

    Science.gov (United States)

    Edelstein, Karen S.; McCarty, Robert E.

    The NASA Space Shuttle Orbiter's windshield employs three glass panes separated by air gaps. The brittleness of the glass offers much less birdstrike energy-absorption capability than the laminated polycarbonate windshields of more conventional aircraft; attention must accordingly be given to the risk of catastrophic bird impact, and to methods of strike prevention that address bird populations around landing sites rather than the modification of the window's design. Bird populations' direct reduction, as well as careful scheduling of Orbiter landing times, are suggested as viable alternatives. The question of birdstrike-resistant glass windshield design for hypersonic aerospacecraft is discussed.

  18. Close-up of LSRA Shuttle main gear

    Science.gov (United States)

    1993-01-01

    A space shuttle landing gear system is clearly seen between the two main landing gear components on this NASA CV-990, modified as a Landing Systems Research Aircraft. The space shuttle landing gear test unit, operated by a high-pressure hydraulic system, allowed engineers to assess and document the performance of space shuttle main and nose landing gear systems, tires and wheel assemblies, plus braking and nose wheel steering performance. The series of 155 test missions for the space shuttle program, conducted at NASA's Dryden Flight Research Center, Edwards, California, provided extensive data about the life and endurance of the shuttle tire systems and helped raise the shuttle crosswind landing limits at Kennedy.

  19. Space shuttle program: Shuttle Avionics Integration Laboratory. Volume 7: Logistics management plan

    Science.gov (United States)

    1974-01-01

    The logistics management plan for the shuttle avionics integration laboratory defines the organization, disciplines, and methodology for managing and controlling logistics support. Those elements requiring management include maintainability and reliability, maintenance planning, support and test equipment, supply support, transportation and handling, technical data, facilities, personnel and training, funding, and management data.

  20. SUSTAINABLE CORPORATE AND SUSTAINABLE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    DORU CÎRNU

    2017-06-01

    Full Text Available In recent decades, the image of the international business environment has changed significantly. Studies conducted by UNCTAD shows that corporate phenomenon developments in the world economy is growing. Without claiming to present an exhaustive topic so vast we tried to capture some "facets" of sustainable development from the perspective of multinational corporations, given the expansion of these economic entities and strengthening their power in the global economy. We present more negative aspects of the actions of multinational corporations in terms of sustainable development, it is very important to know both sides of the coin, which will not only help transnational giants including release. Based on issues such as corporate social responsibility, environmental pollution and workers' rights, we sought to counter official statements. The conclusion is that these economic entities are real forces that can not be ignored in today's world and the obvious problem of sustainable development can not be addressed independently of the phenomenon, context we also identified some possible solutions to conflict of corporations and essence of the concept of sustainable development.

  1. Sustainable Consumption

    DEFF Research Database (Denmark)

    Røpke, Inge

    2015-01-01

    in wider social, economic and technological frameworks is emphasised. In particular, the chapter is inspired by practice theory and transition theory. First, various trends in consumption are outlined to highlight some of the challenges for sustainability transitions. Then, it is discussed how consumption...... patterns are shaped over time and what should be considered in sustainability strategies. While discussions on consumption often take their point of departure in the perspective of the individual and then zoom to the wider context, the present approach is the opposite. The outline starts with the basic...... biophysical, distributional and economic conditions for high consumption in rich countries and then zooms in on the coevolution of provision systems and consumption, and how consumption is shaped by practices and projects in everyday life. Furthermore, the paper discusses whether and how transition...

  2. Sustainable Buildings

    DEFF Research Database (Denmark)

    Tommerup, Henrik M.; Elle, Morten

    The scientific community agrees that: all countries must drastically and rapidly reduce their CO2 emissions and that energy efficient houses play a decisive role in this. The general attitude at the workshop on Sustainable Buildings was that we face large and serious climate change problems that ...... that need urgent action. The built environment is an obvious area to put effort into because of the large and cost-effective energy saving potential and potential for Renewable Energy-based supply systems for buildings.......The scientific community agrees that: all countries must drastically and rapidly reduce their CO2 emissions and that energy efficient houses play a decisive role in this. The general attitude at the workshop on Sustainable Buildings was that we face large and serious climate change problems...

  3. STS-81 Shuttle Atlantis clears the tower

    Science.gov (United States)

    1997-01-01

    Like a rising sun lighting up the night, the Space Shuttle Atlantis soars from Launch Pad 39B at 4:27:23 a.m. EST Jan. 12 on its way to dock with the Mir space station for the fifth time. The 10-day mission will feature the transfer of Mission Specialist Jerry Linenger to Mir to replace astronaut John Blaha, who has been on the orbital laboratory since Sept. 19, 1996. The other STS-81 crew members include Mission Commander Michael A. Baker; Pilot Brent W. Jett, Jr.; and Mission Specialists John M. Grunsfeld, Peter J. K. 'Jeff' Wisoff and Marsha S. Ivins. During the five-day docking operations, the Shuttle and Mir crews will conduct risk mitigation, human life science, microgravity and materials processing experiments that will provide data for the design, development and operation of the International Space Station. The primary payload is the SPACEHAB-DM double module that will provide space for more than 2,000 pounds of hardware, food and water that will be transferred into the Russian space station.The SPACEHAB will also be used to return experiment samples from the Mir to Earth for analysis and for microgravity experiments during the mission.

  4. Final Results of Shuttle MMOD Impact Database

    Science.gov (United States)

    Hyde, J. L.; Christiansen, E. L.; Lear, D. M.

    2015-01-01

    The Shuttle Hypervelocity Impact Database documents damage features on each Orbiter thought to be from micrometeoroids (MM) or orbital debris (OD). Data is divided into tables for crew module windows, payload bay door radiators and thermal protection systems along with other miscellaneous regions. The combined number of records in the database is nearly 3000. Each database record provides impact feature dimensions, location on the vehicle and relevant mission information. Additional detail on the type and size of particle that produced the damage site is provided when sampling data and definitive spectroscopic analysis results are available. Guidelines are described which were used in determining whether impact damage is from micrometeoroid or orbital debris impact based on the findings from scanning electron microscopy chemical analysis. Relationships assumed when converting from observed feature sizes in different shuttle materials to particle sizes will be presented. A small number of significant impacts on the windows, radiators and wing leading edge will be highlighted and discussed in detail, including the hypervelocity impact testing performed to estimate particle sizes that produced the damage.

  5. Shuttle orbiter with telescoping main propulsion unit and payload

    Science.gov (United States)

    MacConochie, Ian O.

    1993-03-01

    An improved Space Shuttle with variable internal volume is provided. The Space Shuttle Orbiter includes a telescoping main propulsion unit. This main propulsion unit contains the main rocket engines and fuel tanks and telescopes into the Space Shuttle. A variable cavity is located between this unit and the crew compartment. Accordingly, the positioning of the telescoping main propulsion unit determines the volume of the variable cavity. Thus, the volume of the variable length of the entire Space Shuttle may be increased or decreased to achieve desired configurations for optimal storage. In one embodiment of the invention, the payload also telescopes within the variable cavity.

  6. Recent Shuttle Post Flight MMOD Inspection Highlights

    Science.gov (United States)

    Hyed, James L.; Christiansen, Eric L.; Lear, Dana M.; Herrin, Jason S.

    2009-01-01

    Post flight inspections on the Space Shuttle Atlantis conducted after the STS-11.5 mission revealed a 0.11 inch (2.8 mm) hole in the outer face sheet of the starboard payload bay door radiator panel #4. The payload bay door radiators in this region are 0.5 inch (12.7 mm) thick aluminum honeycomb with 0.011 in (0.279 mm) thick aluminum face sheets topped with 0.005 in (0.127 mm) silver-Teflon tape. Inner face sheet damage included a 0.267 in (6.78 mm) long through crack with measureable deformation in the area of 0.2 in (5.1 mm). There was also a 0.031 in (0.787 nun) diameter hole in the rear face sheet. A large approximately l in (25 mm) diameter region of honeycomb was also destroyed. Since the radiators are located on the inside of the shuttle payload bay doors which are closed during ascent and reentry, the damage could only have occurred during the on-orbit portion of the mission. During the August 2007 STS-118 mission to the International Space Station, a micro-meteoroid or orbital debris (MMOD) particle impacted and completely penetrated one of shuttle Endeavour's radiator panels and the underlying thermal control system (TCS) blanket, leaving deposits on (but no damage to) the payload bay door. While it is not unusual for shuttle orbiters to be impacted by small MMOD particles, the damage from this impact is larger than any previously seen on the shuttle radiator panels. One of the largest impacts ever observed on a crew module window occurred during the November 2008 STS-126 mission to the International Space Station. Damage to the window was documented by the crew on orbit. Post flight inspection revealed a 0.4 in (10.8 mm) crater in the window pane, with a depth of 0.03 in (0.76 mm). The window pane was replaced due to the damage caused by this impact. Analysis performed on residue contained in dental mold impressions taken of the site indicated that a meteoroid particle produced this large damage site. The post flight inspection after the subsequent

  7. The underlying event in proton-proton collisions

    Energy Technology Data Exchange (ETDEWEB)

    Bechtel, F.

    2009-05-15

    In this thesis, studies of the underlying event in proton-proton collisions at a center-of-mass energy of {radical}(s) = 10 TeV are presented. Crucial ingredient to underlying event models are multiple parton-parton scatters in single proton-proton collisions. The feasibility of measuring the underlying event was investigated with the Compact Muon Solenoid (CMS) detector at the Large Hadron Collider (LHC) using charged particles and charged-particle jets. Systematic uncertainties of the underlying event measurement due to detector misalignment and imperfect track reconstruction are found to be negligible after {integral}Ldt=1 pb{sup -1} of data are available. Different model predictions are compared with each other using fully simulated Monte Carlo samples. It is found, that distinct models differ strongly enough to tell them apart with early data. (orig.)

  8. The proton-proton scattering without Coulomb force renormalization

    Directory of Open Access Journals (Sweden)

    Glöckle W.

    2010-04-01

    Full Text Available We demonstrate numerically that proton-proton (pp scattering observables can be determined directly by standard short range methods using a screened pp Coulomb force without renormalization. We numerically investigate solutions of the 3-dimensional Lippmann-Schwinger (LS equation for an exponentially screened Coulomb potential. For the limit of large screening radii we confirm analytically predicted properties for off-shell, half-shell and on-shell elements of the Coulomb t-matrix.

  9. Proton-pumping mechanism of cytochrome c oxidase: A kinetic master-equation approach

    Science.gov (United States)

    Kim, Young C.; Hummer, Gerhard

    2011-01-01

    Cytochrome c oxidase (CcO) is an efficient energy transducer that reduces oxygen to water and converts the released chemical energy into an electrochemical membrane potential. As a true proton pump, CcO translocates protons across the membrane against this potential. Based on a wealth of experiments and calculations, an increasingly detailed picture of the reaction intermediates in the redox cycle has emerged. However, the fundamental mechanism of proton pumping coupled to redox chemistry remains largely unresolved. Here we examine and extend a kinetic master-equation approach to gain insight into redox-coupled proton pumping in CcO. Basic principles of the CcO proton pump emerge from an analysis of the simplest kinetic models that retain essential elements of the experimentally determined structure, energetics, and kinetics, and that satisfy fundamental physical principles. The master-equation models allow us to address the question of how pumping can be achieved in a system in which all reaction steps are reversible. Whereas proton pumping does not require the direct modulation of microscopic reaction barriers, such kinetic gating greatly increases the pumping efficiency. Further efficiency gains can be achieved by partially decoupling the proton uptake pathway from the ative-site region. Such a mechanism is consistent with the proposed Glu valve, in which the side chain of a key glutamic acid shuttles between the D channel and the active-site region. We also show that the models predict only small proton leaks even in the absence of turnover. The design principles identified here for CcO provide a blueprint for novel biology-inspired fuel cells, and the master-equation formulation should prove useful also for other molecular machines. PMID:21946020

  10. Proton radiography to improve proton radiotherapy: Simulation study at different proton beam energies

    CERN Document Server

    Biegun, A K; van Goethem, M-J; van der Graaf, E R; van Beuzekom, M; Visser, J; Brandenburg, S

    2016-01-01

    To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have systematic uncertainties in the calculated proton range in a patient of typically 3-4\\% and even up to 10\\% in region containing bone~\\cite{USchneider1995,USchneider1996,WSchneider2000,GCirrone2007,HPaganetti2012,TPlautz2014,GLandry2013,JSchuemann2014}. As a consequence, part of a tumor may receive no dose, or a very high dose can be delivered in healthy ti\\-ssues and organs at risks~(e.g. brain stem)~\\cite{ACKnopf2013}. A transmission radiograph of high-energy protons measuring proton stopping powers directly will allow to reduce these uncertainties, and thus improve the quality of treatment. The best way to obtain a sufficiently accurate radiograph is by tracking individual protons traversing the phantom (patient)~\\cite{GCirrone2007,TPlautz2014,VSipala2013}. In our simulations ...

  11. Mission Possible: BioMedical Experiments on the Space Shuttle

    Science.gov (United States)

    Bopp, E.; Kreutzberg, K.

    2011-01-01

    Biomedical research, both applied and basic, was conducted on every Shuttle mission from 1981 to 2011. The Space Shuttle Program enabled NASA investigators and researchers from around the world to address fundamental issues concerning living and working effectively in space. Operationally focused occupational health investigations and tests were given priority by the Shuttle crew and Shuttle Program management for the resolution of acute health issues caused by the rigors of spaceflight. The challenges of research on the Shuttle included: limited up and return mass, limited power, limited crew time, and requirements for containment of hazards. The sheer capacity of the Shuttle for crew and equipment was unsurpassed by any other launch and entry vehicle and the Shuttle Program provided more opportunity for human research than any program before or since. To take advantage of this opportunity, life sciences research programs learned how to: streamline the complicated process of integrating experiments aboard the Shuttle, design experiments and hardware within operational constraints, and integrate requirements between different experiments and with operational countermeasures. We learned how to take advantage of commercial-off-the-shelf hardware and developed a hardware certification process with the flexibility to allow for design changes between flights. We learned the importance of end-to-end testing for experiment hardware with humans-in-the-loop. Most importantly, we learned that the Shuttle Program provided an excellent platform for conducting human research and for developing the systems that are now used to optimize research on the International Space Station. This presentation will include a review of the types of experiments and medical tests flown on the Shuttle and the processes that were used to manifest and conduct the experiments. Learning Objective: This paper provides a description of the challenges related to launching and implementing biomedical

  12. Legacy of Biomedical Research During the Space Shuttle Program

    Science.gov (United States)

    Hayes, Judith C.

    2011-01-01

    The Space Shuttle Program provided many opportunities to study the role of spaceflight on human life for over 30 years and represented the longest and largest US human spaceflight program. Outcomes of the research were understanding the effect of spaceflight on human physiology and performance, countermeasures, operational protocols, and hardware. The Shuttle flights were relatively short, Biomedical research was conducted on the Space Shuttle using various vehicle resources. Specially constructed pressurized laboratories called Spacelab and SPACEHAB housed many laboratory instruments to accomplish experiments in the Shuttle s large payload bay. In addition to these laboratory flights, nearly every mission had dedicated human life science research experiments conducted in the Shuttle middeck. Most Shuttle astronauts participated in some life sciences research experiments either as test subjects or test operators. While middeck experiments resulted in a low sample per mission compared to many Earth-based studies, this participation allowed investigators to have repetition of tests over the years on successive Shuttle flights. In addition, as a prelude to the International Space Station (ISS), NASA used the Space Shuttle as a platform for assessing future ISS hardware systems and procedures. The purpose of this panel is to provide an understanding of science integration activities required to implement Shuttle research, review biomedical research, characterize countermeasures developed for Shuttle and ISS as well as discuss lessons learned that may support commercial crew endeavors. Panel topics include research integration, cardiovascular physiology, neurosciences, skeletal muscle, and exercise physiology. Learning Objective: The panel provides an overview from the Space Shuttle Program regarding research integration, scientific results, lessons learned from biomedical research and countermeasure development.

  13. SUSTAINABLE CHEMISTRY FOR SUSTAINABLE INDUSTRY

    Directory of Open Access Journals (Sweden)

    G. Rizzuto

    2015-01-01

    Full Text Available Foundry Alfe Chem is an industrial reality working in the field of lubrication and chemical auxiliaries for industrial processes, which falls within the framework of the emerging and increasingly important «green chemistry». The goal of the company is to develop products that are more environmentally friendly by using raw materials from renewable sources; specifically, Foundry Alfe Chem has a program of self-sustainability that contemplates, for the foreseeable future, the direct production of renewable raw materials. The company has developed a new dedicated product line, Olitema, whose purpose is to offer highly technological solutions with complete environmental sustainability. In this context, Foundry Alfe CHEM has created a new product which represents a breakthrough in the class of HFC hydraulic fluids: Ecosafe Plus is a biodegradable fire-resistant hydraulic fluid with high engineering and technological performances, high environmental sustainability and the best security guarantees in workplaces. Its formulation is glycols-free, and it allows for easier disposal of the exhausted fluid, compared to a traditional water/ glycol-based HFC hydraulic fluid. For what concern the technological properties, Ecosafe Plus has been tested by accredited laboratories with tribological trials (4 Ball wear test ASTM D 4172, Ball on disc test ASTM 6425, Brugger test DIN 51347, Vickers test ASTM D 2882, with elastomer compatibility test (ASTM D 471 and biodegradability test (OECD 310 F.

  14. Proton Radiotherapy for Pediatric Sarcoma

    Directory of Open Access Journals (Sweden)

    Matthew M. Ladra

    2014-01-01

    Full Text Available Pediatric sarcomas represent a distinct group of pathologies, with approximately 900 new cases per year in the United States alone. Radiotherapy plays an integral role in the local control of these tumors, which often arise adjacent to critical structures and growing organs. The physical properties of proton beam radiotherapy provide a distinct advantage over standard photon radiation by eliminating excess dose deposited beyond the target volume, thereby reducing both the dose of radiation delivered to non-target structures as well as the total radiation dose delivered to a patient. Dosimetric studies comparing proton plans to IMRT and 3D conformal radiation have demonstrated the superiority of protons in numerous pediatric malignancies and data on long-term clinical outcomes and toxicity is emerging. In this article, we review the existing clinical and dosimetric data regarding the use of proton beam radiation in malignant bone and soft tissue sarcomas.

  15. Protonation Equilibrium of Linear Homopolyacids

    Directory of Open Access Journals (Sweden)

    Požar J.

    2015-07-01

    Full Text Available The paper presents a short summary of investigations dealing with protonation equilibrium of linear homopolyacids, in particularly those of high charge density. Apart from the review of experimental results which can be found in the literature, a brief description of theoretical models used in processing the dependence of protonation constants on monomer dissociation degree and ionic strength is given (cylindrical model based on Poisson-Boltzmann equation, cylindrical Stern model, the models according to Ising, Högfeldt, Mandel and Katchalsky. The applicability of these models regarding the polyion charge density, electrolyte concentration and counterion type is discussed. The results of Monte Carlo simulations of protonation equilibrium are also briefly mentioned. In addition, frequently encountered errors connected with calibration of of glass electrode and the related unreliability of determined protonation constants are pointed out.

  16. Proton Football European Championship 2016

    CERN Multimedia

    2016-01-01

    Check out the European championship of proton football 2016 at CERN. Produced by: CERN Audiovisual Productions Service Director: Jacques Fichet Editor: Jacques Fichet Music : Burnt of Jingle Punks You can follow us on:

  17. Sustainable Procurement

    DEFF Research Database (Denmark)

    Telles, Pedro; Ølykke, Grith Skovgaard

    2017-01-01

    and within it how sustainable requirements have increased the level of compliance required, particularly regulatory compliance. Compliance was already present in previous EU public procurement frameworks, but its extent on Directive 2014/24/EU leads the authors to consider the current legal framework...... as subject to substantial regulatory compliance obligations external to the process of procurement. In short, procurement has been transformed in a way to enforce regulatory obligations that are not intrinsic to the process of buying. This leads to the conclusion that questions such as the cost and trade...

  18. Kaon photoproduction off proton

    Directory of Open Access Journals (Sweden)

    Skoupil Dalibor

    2016-01-01

    Full Text Available We have recently constructed our version of the Regge-plus-resonance (RPR model and two variants of an isobar model for photoproduction of kaons on the proton, utilizing new experimental data from CLAS, LEPS, and GRAAL collaborations for adjusting free parameters of the models. Higher-spin nucleon (3/2 and 5/2 and hyperon (3/2 resonances were included using the consistent formalism by Pascalutsa and found to play an important role in data description. The set of chosen nucleon resonances in our new isobar models agrees well with the set of the most probable contributing states determined in the Bayesian analysis with the RPR model whilst only 6 out of 10 N*’s selected in the RPR fit of ours overlap with the nucleon resonant states in the Bayesian analysis. Results of two versions of the isobar model are compared to the new version of the RPR model and experimental data in the third-resonance region and their properties are discussed. We place an emphasis on the choice of resonances, the predictions in the forward- and backward-angle region as well as the choice of the hadron form factor.

  19. Parametric Model for Astrophysical Proton-Proton Interactions and Applications

    Energy Technology Data Exchange (ETDEWEB)

    Karlsson, Niklas [KTH Royal Institute of Technology, Stockholm (Sweden)

    2007-01-01

    Observations of gamma-rays have been made from celestial sources such as active galaxies, gamma-ray bursts and supernova remnants as well as the Galactic ridge. The study of gamma rays can provide information about production mechanisms and cosmic-ray acceleration. In the high-energy regime, one of the dominant mechanisms for gamma-ray production is the decay of neutral pions produced in interactions of ultra-relativistic cosmic-ray nuclei and interstellar matter. Presented here is a parametric model for calculations of inclusive cross sections and transverse momentum distributions for secondary particles--gamma rays, e±, ve, $\\bar{v}$e, vμ and $\\bar{μ}$e--produced in proton-proton interactions. This parametric model is derived on the proton-proton interaction model proposed by Kamae et al.; it includes the diffraction dissociation process, Feynman-scaling violation and the logarithmically rising inelastic proton-proton cross section. To improve fidelity to experimental data for lower energies, two baryon resonance excitation processes were added; one representing the Δ(1232) and the other multiple resonances with masses around 1600 MeV/c2. The model predicts the power-law spectral index for all secondary particle to be about 0.05 lower in absolute value than that of the incident proton and their inclusive cross sections to be larger than those predicted by previous models based on the Feynman-scaling hypothesis. The applications of the presented model in astrophysics are plentiful. It has been implemented into the Galprop code to calculate the contribution due to pion decays in the Galactic plane. The model has also been used to estimate the cosmic-ray flux in the Large Magellanic Cloud based on HI, CO and gamma-ray observations. The transverse momentum distributions enable calculations when the proton distribution is anisotropic. It is shown that the gamma-ray spectrum and flux due to a

  20. Proton Structure and PHENIX Experiment

    OpenAIRE

    Qiu, Jian-Wei

    2015-01-01

    We briefly summarize the important and critical roles that PHENIX Experiment has played in determining the proton's internal structure in terms of quarks and gluons, and their dynamics. Some pioneering measurements by PHENIX Experiment on the motion and polarization of quarks and gluons, as well as their correlations inside a fast moving proton are presented. Some future opportunities and potentials of PHENIX Experiment are also discussed.

  1. Voltage-gated Proton Channels

    Science.gov (United States)

    DeCoursey, Thomas E.

    2014-01-01

    Voltage-gated proton channels, HV1, have vaulted from the realm of the esoteric into the forefront of a central question facing ion channel biophysicists, namely the mechanism by which voltage-dependent gating occurs. This transformation is the result of several factors. Identification of the gene in 2006 revealed that proton channels are homologues of the voltage-sensing domain of most other voltage-gated ion channels. Unique, or at least eccentric, properties of proton channels include dimeric architecture with dual conduction pathways, perfect proton selectivity, a single-channel conductance ~103 smaller than most ion channels, voltage-dependent gating that is strongly modulated by the pH gradient, ΔpH, and potent inhibition by Zn2+ (in many species) but an absence of other potent inhibitors. The recent identification of HV1 in three unicellular marine plankton species has dramatically expanded the phylogenetic family tree. Interest in proton channels in their own right has increased as important physiological roles have been identified in many cells. Proton channels trigger the bioluminescent flash of dinoflagellates, facilitate calcification by coccolithophores, regulate pH-dependent processes in eggs and sperm during fertilization, secrete acid to control the pH of airway fluids, facilitate histamine secretion by basophils, and play a signaling role in facilitating B-cell receptor mediated responses in B lymphocytes. The most elaborate and best-established functions occur in phagocytes, where proton channels optimize the activity of NADPH oxidase, an important producer of reactive oxygen species. Proton efflux mediated by HV1 balances the charge translocated across the membrane by electrons through NADPH oxidase, minimizes changes in cytoplasmic and phagosomal pH, limits osmotic swelling of the phagosome, and provides substrate H+ for the production of H2O2 and HOCl, reactive oxygen species crucial to killing pathogens. PMID:23798303

  2. Sustainable consumption and marketing

    NARCIS (Netherlands)

    Dam, van Y.K.

    2016-01-01

    Sustainable development in global food markets is hindered by the discrepancy between positive consumer attitudes towards sustainable development or sustainability and the lack of corresponding sustainable consumption by a majority of consumers. Apparently for many (light user) consumers the

  3. Comprehensive Shuttle Foam Debris Reduction Strategies

    Science.gov (United States)

    Semmes, Edmund B.

    2007-01-01

    The Columbia Accident Investigation Board (CAIB) was clear in its assessment of the loss of the Space Shuttle Columbia on February 3, 2003. Foam liberated from the External Tank (ET) impacting the brittle wing leading edge (WLE) of the orbiter causing the vehicle to disintegrate upon re-entry. Naturally, the CAB pointed out numerous issues affecting this exact outcome in hopes of correcting systems of systems failures any one of which might have altered the outcome. However, Discovery s recent return to flight (RTF) illustrates the primacy of erosion of foam and the risk of future undesirable outcomes. It is obvious that the original RTF focused approach to this problem was not equal to a comprehensive foam debris reduction activity consistent with the high national value of the Space Shuttle assets. The root cause is really very simple when looking at the spray-on foam insulation for the entire ET as part of the structure (e.g., actual stresses > materials allowable) rather than as some sort of sizehime limited ablator. This step is paramount to accepting the CAB recommendation of eliminating debris or in meeting any level of requirements due to the fundamental processes ensuring structural materials maintain their integrity. Significant effort has been expended to identify root cause of the foam debris In-Flight Anomaly (FA) of STS-114. Absent verifiable location specific data pre-launch (T-0) and in-flight, only a most probable cause can be identified. Indeed, the literature researched corroborates NASNTM-2004-2 13238 disturbing description of ill defined materials characterization, variable supplier constituents and foam processing irregularities. Also, foam is sensitive to age and the exposed environment making baseline comparisons difficult without event driven data. Conventional engineering processes account for such naturally occurring variability by always maintaining positive margins. Success in a negative margin range is not consistently achieved

  4. Shuttle payload minimum cost vibroacoustic tests

    Science.gov (United States)

    Stahle, C. V.; Gongloff, H. R.; Young, J. P.; Keegan, W. B.

    1977-01-01

    This paper is directed toward the development of the methodology needed to evaluate cost effective vibroacoustic test plans for Shuttle Spacelab payloads. Statistical decision theory is used to quantitatively evaluate seven alternate test plans by deriving optimum test levels and the expected cost for each multiple mission payload considered. The results indicate that minimum costs can vary by as much as $6 million for the various test plans. The lowest cost approach eliminates component testing and maintains flight vibration reliability by performing subassembly tests at a relatively high acoustic level. Test plans using system testing or combinations of component and assembly level testing are attractive alternatives. Component testing alone is shown not to be cost effective.

  5. Space shuttle crew training at CERN

    CERN Multimedia

    Paola Catapano

    From 13 to 16 October, the crew of NASA Space Shuttle mission STS-134 came to CERN for a special physics training programme. Invited here by Samuel Ting, they will deliver the Alpha Magnetic Spectrometer (AMS) detector to the International Space Station (ISS).   The STS134 crew in the Lodge at the Aiguille du Midi wearing CERN fleeces. From left to right: Captain Mark Kelly, US Navy; Pilot Gregory Johnson, USAF ret.; Mission Specialist Andrew Feustel; Mission Specialist Mike Fincke, USAF, Mission Specialist Gregory Chamitoff and Mission Specialist Roberto Vittori, ESA and Italian Air Force. Headed by Commander Mark Kelly, a US Navy captain, the crew included pilot Gregory Johnson, a US Air Force (USAF) colonel, and mission specialists Mike Fincke (also a USAF Colonel), Andrew Feustel, and Gregory Chamitoff of NASA, as well as Colonel Roberto Vittori of the European Space Agency (ESA). Two flight directors, Gary Horlache and Derek Hassmann of NASA, and the engineer responsible for the Ext...

  6. Heat pipe applications for the space shuttle.

    Science.gov (United States)

    Tawil, M.; Alario, J.; Prager, R.; Bullock, R.

    1972-01-01

    Discussion of six specific applications for heat pipe (HP) devices on the space shuttle. These applications were chosen from 27 concepts formulated as part of a study to evaluate the potential benefits associated with HP use. The formulation process is briefly described along with the applications which evolved. The bulk of the discussion deals with the 'top' six - namely, HP radiators for waste heat rejection, an HP augmented cold rail, an HP circuit for electronic equipment cooling, modular heat sink for control of remote packages, an HP temperature control for compartments, and air-cooled equipment racks. The philosophy, physical design details, and performance data are presented for each concept along with a comparison with the baseline design where applicable.

  7. Collins named First Woman Shuttle Commander

    Science.gov (United States)

    Showstack, Randy

    Just a few hours after NASA revealed that there is water ice on the Moon, U.S. First Lady Hillary Rodham Clinton introduced Air Force Lieutenant Colonel Eileen Collins to a packed auditorium at Dunbar Senior High School in Washington, D.C., as the first woman who will command a NASA space shuttle mission. With students at this school, which is noted for its pre-engineering program, cheering, Clinton said that Collins' selection “is one big step forward for women and one giant step for humanity.” Clinton added, “It doesn't matter if you are a boy or a girl, you can be an astronaut or a pilot, if you get a first-rate education in math and science.”

  8. Space Shuttle food galley design concept

    Science.gov (United States)

    Heidelbaugh, N. D.; Smith, M. C.; Fischer, R.; Cooper, B.

    1974-01-01

    A food galley has been designed for the crew compartment of the NASA Space Shuttle Orbiter. The rationale for the definition of this design was based upon assignment of priorities to each functional element of the total food system. Principle priority categories were assigned in the following order: food quality, nutrition, food packaging, menu acceptance, meal preparation efficiency, total system weight, total system volume, and total power requirements. Hence, the galley was designed using an 'inside-out' approach which first considered the food and related biological functions and subsequently proceeded 'outward' from the food to encompass supporting hardware. The resulting galley is an optimal design incorporating appropriate priorities for trade-offs between biological and engineering constraints. This design approach is offered as a model for the design of life support systems.

  9. Dynamics of gradient formation by intracellular shuttling

    Energy Technology Data Exchange (ETDEWEB)

    Berezhkovskii, Alexander M. [Mathematical and Statistical Computing Laboratory, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20892 (United States); Shvartsman, Stanislav Y. [Department of Chemical and Biological Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544 (United States)

    2015-08-21

    A number of important cellular functions rely on the formation of intracellular protein concentration gradients. Experimental studies discovered a number of mechanisms for the formation of such gradients. One of the mechanisms relies on the intracellular shuttling of a protein that interconverts between the two states with different diffusivities, under the action of two enzymes, one of which is localized to the plasma membrane, whereas the second is uniformly distributed in the cytoplasm. Recent work reported an analytical solution for the steady state gradient in this mechanism, obtained in the framework of a one-dimensional reaction-diffusion model. Here, we study the dynamics in this model and derive analytical expressions for the Laplace transforms of the time-dependent concentration profiles in terms of elementary transcendental functions. Inverting these transforms numerically, one can obtain time-dependent concentration profiles of the two forms of the protein.

  10. Echocardiographic evaluation of Space Shuttle crewmembers

    Science.gov (United States)

    Bungo, M. W.; Goldwater, D. J.; Popp, R. L.; Sandler, H.

    1987-01-01

    Echocardiographic measurements of left ventricular volume were obtained from 17 members of four Space Shuttle crews before and after 5- to 8-day space flights. Measurements obtained 1 h after landing indicated increases in the heart rate (HR), mean arterial pressure, and systemic vascular resistance values. On the other hand, the end-diastolic volume index (EDVI) fell 17 ml/sq m, and the stroke volume index (SVI) fell 15 ml/sq m. Measurements taken 1-2 weeks later demonstrated that the HR values returned to normal, but the EDVI and SVI values remained significantly below preflight levels, despite the ability of the subjects to ambulate and exercise. The results indicate that a space flight induces significant changes in heart volume affecting the left-ventricle function. It is suggested that the prolonged recovery period is related to the high level of aerobic conditioning in these subjects.

  11. Subjective Sleep Experience During Shuttle Missions

    Science.gov (United States)

    Whitmire, Alexandra; Slack, Kelley; Locke, James; Patterson, Holly; Faulk, Jeremy; Keeton, Kathryn; Leveton, Lauren

    2012-01-01

    It is now known that for many astronauts, sleep is reduced in spaceflight. Given that sleep is intimately tied to performance, safety, health, and well being, it is important to characterize factors that hinder sleep in space, so countermeasures can be implemented. Lessons learned from current spaceflight can be used to inform the development of space habitats and mitigation strategies for future exploration missions. The purpose of this study was to implement a survey and one-on-one interviews to capture Shuttle flyers' subjective assessment of the factors that interfered with a "good nights sleep" during their missions. Strategies that crewmembers reported using to improve their sleep quality during spaceflight were also discussed. Highlights from the interview data are presented here.

  12. Generation of proton aurora by magnetosonic waves.

    Science.gov (United States)

    Xiao, Fuliang; Zong, Qiugang; Wang, Yongfu; He, Zhaoguo; Su, Zhenpeng; Yang, Chang; Zhou, Qinghua

    2014-06-05

    Earth's proton aurora occurs over a broad MLT region and is produced by the precipitation of low-energy (2-10 keV) plasmasheet protons. Proton precipitation can alter chemical compositions of the atmosphere, linking solar activity with global climate variability. Previous studies proposed that electromagnetic ion cyclotron waves can resonate with protons, producing proton scattering precipitation. A long-outstanding question still remains whether there is another mechanism responsible for the proton aurora. Here, by performing satellite data analysis and diffusion equation calculations, we show that fast magnetosonic waves can produce trapped proton scattering that yields proton aurora. This provides a new insight into the mechanism of proton aurora. Furthermore, a ray-tracing study demonstrates that magnetosonic wave propagates over a broad MLT region, consistent with the global distribution of proton aurora.

  13. When the proton becomes larger

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    The TOTEM experiment at the LHC has just confirmed that, at high energy, protons behave as if they were becoming larger. In more technical terms, their total cross-section – a parameter linked to the proton-proton interaction probability – increases with energy. This phenomenon, expected from previous measurements performed at much lower energy, has now been confirmed for the first time at the LHC’s unprecedented energy.   One arm of a TOTEM T2 detector during its installation at interaction point 5. A composite particle like the proton is a complex system that in no way resembles a static Lego construction: sub-components move inside and interactions keep the whole thing together, but in a very dynamic way. This partly explains why even the very common proton can still be hiding secrets about its nature, decades after its discovery. One way of studying the inner properties of protons is to observe how they interact with each other, which, in technical terms, i...

  14. Stennis Holds Last Planned Space Shuttle Engine Test

    Science.gov (United States)

    2009-01-01

    With 520 seconds of shake, rattle and roar on July 29, 2009 NASA's John C. Stennis Space Center marked the end of an era for testing the space shuttle main engines that have powered the nation's Space Shuttle Program for nearly three decades.

  15. Astronaut Linda Godwin uses Shuttle Amateur Radio Experiment

    Science.gov (United States)

    1994-01-01

    Onboard the Space Shuttle Endeavour, Astronaut Linda M. Godwin uses the Shuttle Amateur Radio Experiment (SAREX). The payload commander, as well as several other STS-59 crew members, spent some off-duty time using the amateur radio experiment to communicate with 'Hams' and students on Earth.

  16. 14 CFR 1214.802 - Relationship to Shuttle policy.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Relationship to Shuttle policy. 1214.802 Section 1214.802 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for Spacelab Services § 1214.802 Relationship to Shuttle policy. Except as specifically noted, the...

  17. SR proteins: To shuttle or not to shuttle, that is the question.

    Science.gov (United States)

    Hammarskjold, Marie-Louise; Rekosh, David

    2017-07-03

    Serine- and arginine-rich proteins play important roles in splicing, nuclear export, and translation. In this issue, Botti et al. (2017. J. Cell Biol https://doi.org/10.1083/jcb.201610051) show that SRSF2 and SRSF5, previously thought to be nuclear, shuttle with messenger RNA to the cytoplasm in pluripotent P19 cells, but not in differentiated cells. © 2017 Hammarskjold and Rekosh.

  18. Proton-driven sucrose symport and antiport are provided by the vacuolar transporters SUC4 and TMT1/2.

    Science.gov (United States)

    Schulz, Alexander; Beyhl, Diana; Marten, Irene; Wormit, Alexandra; Neuhaus, Ekkehard; Poschet, Gernot; Büttner, Michael; Schneider, Sabine; Sauer, Norbert; Hedrich, Rainer

    2011-10-01

    The vacuolar membrane is involved in solute uptake into and release from the vacuole, which is the largest plant organelle. In addition to inorganic ions and metabolites, large quantities of protons and sugars are shuttled across this membrane. Current models suggest that the proton gradient across the membrane drives the accumulation and/or release of sugars. Recent studies have associated AtSUC4 with the vacuolar membrane. Some members of the SUC family are plasma membrane proton/sucrose symporters. In addition, the sugar transporters TMT1 and TMT2, which are localized to the vacuolar membrane, have been suggested to function in proton-driven glucose antiport. Here we used the patch-clamp technique to monitor carrier-mediated sucrose transport by AtSUC4 and AtTMTs in intact Arabidopsis thaliana mesophyll vacuoles. In the whole-vacuole configuration with wild-type material, cytosolic sucrose-induced proton currents were associated with a proton/sucrose antiport mechanism. To identify the related transporter on one hand, and to enable the recording of symporter-mediated currents on the other hand, we electrophysiologically characterized vacuolar proteins recognized by Arabidopsis mutants of partially impaired sugar compartmentation. To our surprise, the intrinsic sucrose/proton antiporter activity was greatly reduced when vacuoles were isolated from plants lacking the monosaccharide transporter AtTMT1/TMT2. Transient expression of AtSUC4 in this mutant background resulted in proton/sucrose symport activity. From these studies, we conclude that, in the natural environment within the Arabidopsis cell, AtSUC4 most likely catalyses proton-coupled sucrose export from the vacuole. However, TMT1/2 probably represents a proton-coupled antiporter capable of high-capacity loading of glucose and sucrose into the vacuole. © 2011 The Authors. The Plant Journal © 2011 Blackwell Publishing Ltd.

  19. CERN Shuttles – TRAM arrival – Two additional shuttles as from 2 May 2011

    CERN Multimedia

    General Infrastructure Services Department

    2011-01-01

    With the TRAM’s arrival at CERN and to facilitate mobility inside CERN, the GS Department is reinforcing CERN's shuttle services and will provide users with two additional shuttles from/to Building 33 (CERN Reception) as from Monday 2 May: Circuit No. 5: serving the Meyrin site (approx. every 15 minutes) •\tfrom 7·30 to 9·15 •\tfrom 11·30 to 13·28 (serving restaurants Nos.1 and 2) •\tfrom 16·30 to 18·35   Circuit No. 6: serving the Prevessin site (approx. every 20 minutes) •\tfrom 7·30 to 9·10 •\tfrom 11·30 to 13·28 (serving restaurants Nos. 1, 2 and 3) •\tfrom 16·30 to 18·23 For further details, please consult the timetable for these circuits at the following url: http://gs-dep.web.cern.ch/gs-dep/groups/SEM/ls/ShuttleService/ Please do not hesitate to give us your feedback...

  20. Sparse-view proton computed tomography using modulated proton beams

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jiseoc; Kim, Changhwan; Cho, Seungryong, E-mail: scho@kaist.ac.kr [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejon 305-701 (Korea, Republic of); Min, Byungjun [Department of Radiation Oncology, Kangbuk Samsung Hospital, 110–746 (Korea, Republic of); Kwak, Jungwon [Department of Radiation Oncology, Asan Medical Center, 138–736 (Korea, Republic of); Park, Seyjoon; Lee, Se Byeong [Proton Therapy Center, National Cancer Center, 410–769 (Korea, Republic of); Park, Sungyong [Proton Therapy Center, McLaren Cancer Institute, Flint, Michigan 48532 (United States)

    2015-02-15

    Purpose: Proton imaging that uses a modulated proton beam and an intensity detector allows a relatively fast image acquisition compared to the imaging approach based on a trajectory tracking detector. In addition, it requires a relatively simple implementation in a conventional proton therapy equipment. The model of geometric straight ray assumed in conventional computed tomography (CT) image reconstruction is however challenged by multiple-Coulomb scattering and energy straggling in the proton imaging. Radiation dose to the patient is another important issue that has to be taken care of for practical applications. In this work, the authors have investigated iterative image reconstructions after a deconvolution of the sparsely view-sampled data to address these issues in proton CT. Methods: Proton projection images were acquired using the modulated proton beams and the EBT2 film as an intensity detector. Four electron-density cylinders representing normal soft tissues and bone were used as imaged object and scanned at 40 views that are equally separated over 360°. Digitized film images were converted to water-equivalent thickness by use of an empirically derived conversion curve. For improving the image quality, a deconvolution-based image deblurring with an empirically acquired point spread function was employed. They have implemented iterative image reconstruction algorithms such as adaptive steepest descent-projection onto convex sets (ASD-POCS), superiorization method–projection onto convex sets (SM-POCS), superiorization method–expectation maximization (SM-EM), and expectation maximization-total variation minimization (EM-TV). Performance of the four image reconstruction algorithms was analyzed and compared quantitatively via contrast-to-noise ratio (CNR) and root-mean-square-error (RMSE). Results: Objects of higher electron density have been reconstructed more accurately than those of lower density objects. The bone, for example, has been reconstructed

  1. Virtual Sustainability

    Directory of Open Access Journals (Sweden)

    William Sims Bainbridge

    2010-09-01

    Full Text Available In four ways, massively multiplayer online role-playing games may serve as tools for advancing sustainability goals, and as laboratories for developing alternatives to current social arrangements that have implications for the natural environment. First, by moving conspicuous consumption and other usually costly status competitions into virtual environments, these virtual worlds might reduce the need for physical resources. Second, they provide training that could prepare individuals to be teleworkers, and develop or demonstrate methods for using information technology to replace much transportation technology, notably in commuting. Third, virtual worlds and online games build international cooperation, even blending national cultures, thereby inching us toward not only the world consciousness needed for international agreements about the environment, but also toward non-spatial government that cuts across archaic nationalisms. Finally, realizing the potential social benefits of this new technology may urge us to reconsider a number of traditional societal institutions.

  2. Sustainability; Sustentabilidade

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-10-15

    This chapter analyses the production chain of ethanol, considering the impacts on the quality of the air, water supplies, soil occupation and biodiversity, and the efforts for the soil preservation. It is pointed out the activities of the production cycle and use of bio ethanol due to great uncertainties as far the environmental impacts is concerning and that will deserve more attention in future evaluations. At same time, the chapter highlights another activities where the present acknowledge is sufficient to assure the control and/or prediction of consequences of the desired intervention on the environment media to accommodate the sugar and ethanol production expansion. The consideration is not conservative but to promote the sustainable development.

  3. Sustainability Science Needs Sustainable Data!

    Science.gov (United States)

    Downs, R. R.; Chen, R. S.

    2013-12-01

    Sustainability science (SS) is an 'emerging field of research dealing with the interactions between natural and social systems, and with how those interactions affect the challenge of sustainability: meeting the needs of present and future generations while substantially reducing poverty and conserving the planet's life support systems' (Kates, 2011; Clark, 2007). Bettencourt & Kaur (2011) identified more than 20,000 scientific papers published on SS topics since the 1980s with more than 35,000 distinct authors. They estimated that the field is currently growing exponentially, with the number of authors doubling approximately every 8 years. These scholars are undoubtedly using and generating a vast quantity and variety of data and information for both SS research and applications. Unfortunately we know little about what data the SS community is actually using, and whether or not the data that SS scholars generate are being preserved for future use. Moreover, since much SS research is conducted by cross-disciplinary, multi-institutional teams, often scattered around the world, there could well be increased risks of data loss, reduced data quality, inadequate documentation, and poor long-term access and usability. Capabilities and processes therefore need to be established today to support continual, reliable, and efficient preservation of and access to SS data in the future, especially so that they can be reused in conjunction with future data and for new studies not conceived in the original data collection activities. Today's long-term data stewardship challenges include establishing sustainable data governance to facilitate continuing management, selecting data to ensure that limited resources are focused on high priority SS data holdings, securing sufficient rights to allow unforeseen uses, and preparing data to enable use by future communities whose specific research and information needs are not yet known. Adopting sustainable models for archival

  4. Water and proton transport properties of hexafluorinated sulfonated poly(arylenethioethersulfone) copolymers for applications to proton exchange membrane fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Khalfan, Amish N.; Sanchez, Luz M.; Kodiweera, Chandana; Greenbaum, Steve G. [Hunter College of the City University of New York, Physics Department, 695 Park Avenue, New York, NY 10021 (United States); Bai, Zongwu [University of Dayton Research Institute, University of Dayton, 300 College Park Drive, Dayton, OH 45469 (United States); Dang, Thuy D. [Air Force Research Laboratory/MLBP, Material and Manufacturing Directorate, Wright-Patterson Air Force Base, OH 45433 (United States)

    2007-11-15

    In the present study, we examine the water and proton transport properties of hexafluorinated sulfonated poly(arylenethioethersulfone) (6F-SPTES) copolymer membranes for applications to proton exchange membrane fuel cells (PEMFCs). The 6F-SPTES copolymer membranes build upon the structures of previously studied sulfonated poly(arylenethioethersulfone) (SPTES) copolymer membranes to include CF{sub 3} functional groups in efforts to strengthen water retention and extend membrane performance at elevated temperatures (above 120 C). The 6F-SPTES copolymer membranes sustain higher water self-diffusion and greater proton conductivities than the commercial Nafion {sup registered} membrane. Water diffusion studies of the 6F-SPTES copolymer membranes using the pulsed-field gradient spin-echo NMR technique reveal, however, the fluorinated membranes to be somewhat unfavorable over their non-fluorinated counterparts as high temperature membranes. In addition, proton conductivity measurements of the fluorinated membranes up to 85 C show comparable results with the non-fluorinated SPTES membranes. (author)

  5. Proton-proton Scattering Above 3 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    A. Sibirtsev, J. Haidenbauer, H.-W. Hammer S. Krewald ,Ulf-G. Meissner

    2010-01-01

    A large set of data on proton-proton differential cross sections, analyzing powers and the double-polarization parameter A{sub NN} is analyzed employing the Regge formalism. We find that the data available at proton beam momenta from 3 GeV/c to 50 GeV/c exhibit features that are very well in line with the general characteristics of Regge phenomenology and can be described with a model that includes the {rho}, {omega}, f{sub 2}, and a{sub 2} trajectories and single-Pomeron exchange. Additional data, specifically for spin-dependent observables at forward angles, would be very helpful for testing and refining our Regge model.

  6. A simple solution of the proton crisis

    CERN Document Server

    Pankovic, Vladan

    2014-01-01

    In this work we suggest a simple theoretical model of the proton able to effectively solve proton spin crisis. Within domain of applicability of this simple model proton consists only of two u quarks and one d quarks (two of which have spin opposite to proton and one identical to proton) and one neutral vector phi meson (with spin two times larger than proton spin and directed identically to proton spin). This model is in full agreement not only with existing DIS experiments, but also with spin and electric charge conservation as well as in a satisfactory agreement with rest mass-energy conservation (since phi meson mass is close to proton rest mass). Our model opens an interesting possibility of the solution of the quarks and leptons families problem (proton is not an absolutely non-strange particle, but only a particle with almost totally effectively hidden strange).

  7. Elucidation of the proton transport mechanism in human carbonic anhydrase II.

    Science.gov (United States)

    Maupin, C Mark; McKenna, Robert; Silverman, David N; Voth, Gregory A

    2009-06-10

    Human carbonic anhydrase II (HCA II) is one of the fastest known enzymes, which utilizes a rate-limiting proton transport (PT) step in its enzymatic reaction. To evaluate the PT event at an atomistic level, the multistate empirical valence bond (MS-EVB) method has been utilized in this work. It is observed that the PT event in HCA II exploits a transient active site water cluster to transport the excess proton between the catalytic zinc-bound water/hydroxide and the proton shuttling residue, His64. This PT event is found to be dependent on the enzyme's ability to form and stabilize the active site water cluster in addition to its ability to orient His64 in a favorable conformation. Evaluation of the PT free energy barrier for different orientations of His64 reveals this residue's vital role as a proton transporter and elucidates its direct effect on the barrier to PT through the active site water. It is suggested that the rate-limiting step oscillates between the active site water PT event to His64 and the de/protonation of His64 depending on the exogenous buffer concentration and the orientation of His64. In the absence of a PT acceptor/donor at position 64, it is found that the excess proton will utilize one of three distinct paths to enter/leave the active site. This latter result not only allows for an increased understanding of how enzymes capitalize on the protein/solvent interface to guide excess protons to/from areas of interest, it also provides valuable insight into the chemical rescue experiments on HCA II mutants.

  8. Nucleocytoplasmic shuttling activity of ataxin-3.

    Directory of Open Access Journals (Sweden)

    Sandra Macedo-Ribeiro

    2009-06-01

    Full Text Available Spinocerebellar ataxia type-3, also known as Machado-Joseph Disease (MJD, is one of many inherited neurodegenerative disorders caused by polyglutamine-encoding CAG repeat expansions in otherwise unrelated genes. Disease protein misfolding and aggregation, often within the nucleus of affected neurons, characterize polyglutamine disorders. Several evidences have implicated the nucleus as the primary site of pathogenesis for MJD. However, the molecular determinants for the nucleocytoplasmic transport of human ataxin-3 (Atx3, the protein which is mutated in patients with MJD, are not characterized. In order to characterize the nuclear shuttling activity of Atx3, we performed yeast nuclear import assays and found that Atx3 is actively imported into the nucleus, by means of a classical nuclear localizing sequence formed by a cluster of lysine and arginine residues. On the other hand, when active nuclear export was inhibited using leptomycin B, a specific inhibitor of the nuclear export receptor CRM1, both endogenous Atx3 and transfected GFP-Atx3 accumulated inside the nucleus of a subpopulation of COS-7 cells, whereas both proteins are normally predominant in the cytoplasm. Additionally, using a Rev(1.4-GFP nuclear export assay, we performed an extensive analysis of six putative aliphatic nuclear export motifs identified in Atx3 amino acid sequence. Although none of the tested peptide sequences were found to drive nuclear export when isolated, we have successfully mapped the region of Atx3 responsible for its CRM1-independent nuclear export activity. Curiously, the N-terminal Josephin domain alone is exported into the cytoplasm, but the nuclear export activity of Atx3 is significantly enhanced in a longer construct that is truncated after the two ubiquitin interaction motifs, upstream from the polyQ tract. Our data show that Atx3 is actively imported to and exported from the cell nucleus, and that its nuclear export activity is dependent on a motif

  9. Measurement of Cosmic Ray and Trapped Proton LET Spectra on the STS-95 HOST Mission

    Science.gov (United States)

    Stassinopoulos, E. G.; Barth, J. L.; Stauffer, C. A.

    2017-08-01

    This paper reports on in situ measurements of the linear energy transfer spectra of galactic cosmic rays and their progeny and of trapped Van Allen belt protons as recorded by a pulse height analyzer (PHA) radiation spectrometer which flew on the STS-95 DISCOVERY mission on the Hubble Orbital Systems Test cradle. The shuttle was launched on October 29, 1998 and had a mission duration of 8.5 days during the minimum phase of the solar activity cycle. The orbit of the STS-95 was about 550 km altitude and 28.5° inclination. Close agreement was seen between radiation environment model predictions and the measurements of the PHA. Agreement is obtained by considering the directionality of the radiation interacting with the shuttle structure.

  10. LHC Report: Ions cross protons

    CERN Multimedia

    Reyes Alemany Fernandez for the LHC team

    2013-01-01

    The LHC starts the New Year facing a new challenge: proton-lead collisions in the last month before the shutdown in mid-February.    The first stable beams were achieved on 20 January with 13 individual bunches per beam. In the next fill, the first bunch-trains were injected and stable beams were achieved with 96 proton on 120 ion bunches.  This fill was very important because we were able to study the so-called moving long-range beam-beam encounters. Long-range encounters, which are also seen in proton-proton runs, occur when the bunches in the two beams “see” each other as they travel in the same vacuum chamber at either side of the experiments.  The situation becomes more complicated with proton-lead ions because the two species have different revolution times (until the frequencies are locked at top energy- see “Cogging exercises”) and thus these encounters move. We found that this effect does not cause significant beam losses...

  11. Towards a proton imaging system

    Energy Technology Data Exchange (ETDEWEB)

    Civinini, C., E-mail: Carlo.Civinini@fi.infn.i [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Brianzi, M. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Bruzzi, M. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Dipartimento di Energetica, Universita degli Studi di Firenze, via S. Marta 3, I-50139 Firenze (Italy); Bucciolini, M. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, v.le Morgagni 85, I-50134 Firenze (Italy); Candiano, G. [INFN, Laboratori Nazionali del Sud, via S. Sofia 62, I-95123 Catania (Italy); Capineri, L. [Dipartimento di Elettronica e Telecomunicazioni, Universita degli Studi di Firenze, via S. Marta 3, I-50139 Firenze (Italy); Cirrone, G.A.P.; Cuttone, G. [INFN, Laboratori Nazionali del Sud, via S. Sofia 62, I-95123 Catania (Italy); Lo Presti, D. [Dipartimento di Fisica, Universita degli Studi di Catania, via S. Sofia 64, I-95123 Catania (Italy); INFN, sezione di Catania, via S. Sofia 64, I-95123 Catania (Italy); Marrazzo, L. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, v.le Morgagni 85, I-50134 Firenze (Italy); Mazzaglia, E. [INFN, Laboratori Nazionali del Sud, via S. Sofia 62, I-95123 Catania (Italy); Menichelli, D.; Pieri, S. [INFN, sezione di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Finland) (Italy); Dipartimento di Energetica, Universita degli Studi di Firenze, via S. Marta 3, I-50139 Firenze (Italy); Randazzo, N. [INFN, sezione di Catania, via S. Sofia 64, I-95123 Catania (Italy); Sipala, V. [Dipartimento di Fisica, Universita degli Studi di Catania, via S. Sofia 64, I-95123 Catania (Italy); INFN, sezione di Catania, via S. Sofia 64, I-95123 Catania (Italy)

    2010-11-01

    Hadron therapy for tumor treatment is nowadays used in several medical centres. The main advantage in using protons or light ions beams is the possibility of tightly shaping the radiation dose to the target volume. Presently the spatial accuracy of the therapy is limited by the uncertainty in stopping power distribution, which is derived, for each treatment, from the photon attenuation coefficients measured by X-ray tomography. A direct measurement of the stopping powers will help in reducing this uncertainty. This can be achieved by using a proton beam and a detection system able to reconstruct a tomography image of the patient. As a first step towards such a system an apparatus able to perform a proton transmission radiography (pCR) has been designed. It consists of a silicon microstrip tracker, measuring proton trajectories, and a YAG:Ce calorimeter to determine the particle residual energy. Proton beam and laboratory tests have been performed on the system components prototypes: the main results will be shown and discussed.

  12. The Structure of the Proton

    Science.gov (United States)

    Chambers, E. E.; Hofstadter, R.

    1956-04-01

    The structure and size of the proton have been studied by means of the methods of high-energy electron scattering. The elastic scattering of electrons from protons in polyethylene has been investigated at the following energies in the laboratory system: 200, 300, 400, 500, 550 Mev. The range of laboratory angles examined has been 30 degrees to 135 degrees. At the largest angles and the highest energy, the cross section for scattering shows a deviation below that expected from a point proton by a factor of about nine. The magnitude and variation with angle of the deviations determine a structure factor for the proton, and thereby determine the size and shape of the charge and magnetic-moment distributions within the proton. An interpretation, consistent at all energies and angles and agreeing with earlier results from this laboratory, fixes the rms radius at 0.77 {plus or minus} 0.10 x 10{sup -13} cm for each of the charge and moment distributions. The shape of the density function is not far from a Gaussian with rms radius 0.70 x 10{sup -13} cm or an exponential with rms radius 0.80 x 10 {sup -13} cm. An equivalent interpretation of the experiments would ascribe the apparent size to a breakdown of the Coulomb law and the conventional theory of electromagnetism.

  13. Fundamental plant biology enabled by the space shuttle.

    Science.gov (United States)

    Paul, Anna-Lisa; Wheeler, Ray M; Levine, Howard G; Ferl, Robert J

    2013-01-01

    The relationship between fundamental plant biology and space biology was especially synergistic in the era of the Space Shuttle. While all terrestrial organisms are influenced by gravity, the impact of gravity as a tropic stimulus in plants has been a topic of formal study for more than a century. And while plants were parts of early space biology payloads, it was not until the advent of the Space Shuttle that the science of plant space biology enjoyed expansion that truly enabled controlled, fundamental experiments that removed gravity from the equation. The Space Shuttle presented a science platform that provided regular science flights with dedicated plant growth hardware and crew trained in inflight plant manipulations. Part of the impetus for plant biology experiments in space was the realization that plants could be important parts of bioregenerative life support on long missions, recycling water, air, and nutrients for the human crew. However, a large part of the impetus was that the Space Shuttle enabled fundamental plant science essentially in a microgravity environment. Experiments during the Space Shuttle era produced key science insights on biological adaptation to spaceflight and especially plant growth and tropisms. In this review, we present an overview of plant science in the Space Shuttle era with an emphasis on experiments dealing with fundamental plant growth in microgravity. This review discusses general conclusions from the study of plant spaceflight biology enabled by the Space Shuttle by providing historical context and reviews of select experiments that exemplify plant space biology science.

  14. Shuttle bus services quality assessment Tangerang Selatan toward smart city

    Science.gov (United States)

    Fassa, Ferdinand; Sitorus, Fredy Jhon Philip; Adikesuma, Tri Nugraha

    2017-11-01

    Around the world, shuttle bus operation played the significant role to accommodate transportation for commuting bus passengers. Shuttle Bus services in cities are provided by various bus agencies with kinds of own specific purposes. For instance, at Tangerang Selatan, Indonesia, it was said that shuttle bus In Trans Bintaro is run and operated by private bus companies hire by Bintaro developer. The aim of this research is to identify factors of satisfaction of shuttle bus service in Kota Tangerang Selatan, Indonesia. Several factors are used to analyze sums of 20 parameters performance indicators of Shuttle Bus. A face to face interview using a questionnaire (N=200) was used to collect data on October and March 2017. Likert and diagram Cartesian were used to model the all the parameters. This research succeeded in finding some categories of Shuttle bus service attributes such as accessibility, comfort, and safety. Users agreed that eight indicators in shuttle bus have the excellent achievement, while three indicators on performance remain low and should receive more attention especially punctuality of the bus.

  15. ATLAS proton-proton event containing four muons

    CERN Multimedia

    ATLAS Collaboration

    2011-01-01

    An event with four identified muons from a proton-proton collision in ATLAS. This event is consistent with coming from two Z particles decaying: both Z particles decay to two muons each. Such events are produced by Standard Model processes without Higgs particles. They are also a possible signature for Higgs particle production, but many events must be analysed together in order to tell if there is a Higgs signal. This view is a zoom into the central part of the detector. The four muons are picked out as red tracks. Other tracks and deposits of energy in the calorimeters are shown in yellow.

  16. Concept for a Future Super Proton-Proton Collider

    CERN Document Server

    Tang, Jingyu; Chai, Weiping; Chen, Fusan; Chen, Nian; Chou, Weiren; Dong, Haiyi; Gao, Jie; Han, Tao; Leng, Yongbin; Li, Guangrui; Gupta, Ramesh; Li, Peng; Li, Zhihui; Liu, Baiqi; Liu, Yudong; Lou, Xinchou; Luo, Qing; Malamud, Ernie; Mao, Lijun; Palmer, Robert B.; Peng, Quanling; Peng, Yuemei; Ruan, Manqi; Sabbi, GianLuca; Su, Feng; Su, Shufang; Stratakis, Diktys; Sun, Baogeng; Wang, Meifen; Wang, Jie; Wang, Liantao; Wang, Xiangqi; Wang, Yifang; Wang, Yong; Xiao, Ming; Xing, Qingzhi; Xu, Qingjin; Xu, Hongliang; Xu, Wei; Witte, Holger; Yan, Yingbing; Yang, Yongliang; Yang, Jiancheng; Yuan, Youjin; Zhang, Bo; Zhang, Yuhong; Zheng, Shuxin; Zhu, Kun; Zhu, Zian; Zou, Ye

    2015-01-01

    Following the discovery of the Higgs boson at LHC, new large colliders are being studied by the international high-energy community to explore Higgs physics in detail and new physics beyond the Standard Model. In China, a two-stage circular collider project CEPC-SPPC is proposed, with the first stage CEPC (Circular Electron Positron Collier, a so-called Higgs factory) focused on Higgs physics, and the second stage SPPC (Super Proton-Proton Collider) focused on new physics beyond the Standard Model. This paper discusses this second stage.

  17. Concept for a Future Super Proton-Proton Collider

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Jingyu; et al.

    2015-07-12

    Following the discovery of the Higgs boson at LHC, new large colliders are being studied by the international high-energy community to explore Higgs physics in detail and new physics beyond the Standard Model. In China, a two-stage circular collider project CEPC-SPPC is proposed, with the first stage CEPC (Circular Electron Positron Collier, a so-called Higgs factory) focused on Higgs physics, and the second stage SPPC (Super Proton-Proton Collider) focused on new physics beyond the Standard Model. This paper discusses this second stage.

  18. ATLAS proton-proton event containing two high energy photons

    CERN Multimedia

    ATLAS Collaboration

    2011-01-01

    An event where two energetic photons ("gammas") are produced in a proton-proton collision in ATLAS. Many events of this type are produced by well-understood Standard Model processes ("backgrounds") which do not involve Higgs particles. A small excess of events of this type with similar masses could indicate evidence for Higgs particle production, but any specific event is most likely to be from the background. The photons are indicated, in the different projections and views, by the clusters of energy shown in yellow.

  19. Ecological Impacts of the Space Shuttle Program at John F. Kennedy Space Center, Florida

    Science.gov (United States)

    Hall, Carlton R.; Schmalzer, Paul A.; Breininger, David R.; Duncan, Brean W.; Drese, John H.; Scheidt, Doug A.; Lowers, Russ H.; Reyier, Eric A.; Holloway-Adkins, Karen G.; Oddy, Donna M.; hide

    2014-01-01

    The Space Shuttle Program was one of NASAs first major undertakings to fall under the environmental impact analysis and documentation requirements of the National Environmental Policy Act of 1969 (NEPA). Space Shuttle Program activities at John F. Kennedy Space Center (KSC) and the associated Merritt Island National Wildlife Refuge (MINWR) contributed directly and indirectly to both negative and positive ecological trends in the region through the long-term, stable expenditure of resources over the 40 year program life cycle. These expenditures provided support to regional growth and development in conjunction with other sources that altered land use patterns, eliminated and modified habitats, and contributed to cultural eutrophication of the Indian River Lagoon. At KSC, most Space Shuttle Program related actions were conducted in previously developed facilities and industrial areas with the exception of the construction of the shuttle landing facility (SLF) and the space station processing facility (SSPF). Launch and operations impacts were minimal as a result of the low annual launch rate. The majority of concerns identified during the NEPA process such as potential weather modification, acid rain off site, and local climate change did not occur. Launch impacts from deposition of HCl and particulates were assimilated as a result of the high buffering capacity of the system and low launch and loading rates. Metals deposition from exhaust deposition did not display acute impacts. Sub-lethal effects are being investigated as part of the Resource Conservation and Recovery Act (RCRA) regulatory process. Major positive Space Shuttle Program effects were derived from the adequate resources available at the Center to implement the numerous environmental laws and regulations designed to enhance the quality of the environment and minimize impacts from human activities. This included reduced discharges of domestic and industrial wastewater, creation of stormwater management

  20. New space shuttles; Les enfants de la navette

    Energy Technology Data Exchange (ETDEWEB)

    Ollive, L.

    1999-03-01

    The American space shuttle is the only reusable satellite launcher of today. Several new projects of spatial planes or helicopter rockets are being studied. The Venture Star, planned to replace the shuttle by 2012, is a spatial plane whose prototype named X-33 will have its first flight in summer 2000. The Venture Star will allow a sharp decrease in launching costs: 12000 francs/Kg instead of 10 times as much for the shuttle, the carrying capacity will be 18 tons and the global investment will reach 10 milliard francs. Other projects such as Roton or Astroliner are also briefly presented. (A.C.)

  1. Development of a prototype specialist shuttle vehicle for chipped woodfuel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-06-01

    This report gives details of a project to develop and test a specialist chip shuttle vehicle for conveying woodchips out of the forest with the aim of reducing the cost of woodfuel production. The design objectives are described and include the need to allow easy transfer of the chips from the chipper to the shuttle and on into haulage units, good performance and manoeuvrability on and off roads, and high-tip capacity. Estimates of the improved production and reduced woodfuel production costs are discussed along with the anticipated satisfactory operation of the chipper-shuttle combination in a forestry site.

  2. Shuttle-Mir, CD-ROM Supplement

    Science.gov (United States)

    Morgan, Clay; Launius, Roger (Technical Monitor)

    2001-01-01

    This CD-ROM is a companion to an illustrated history book with the same title. This multi-media, searchable CD includes the full text and images in the book, as well as additional material. Interviews, photographs, and biographies of the U.S. Astronauts, cosmonauts, and team members for the Shuttle-Mir Program are available. STS Mission Summaries for each mission involved can be viewed, including launch and landing details, crew lists, and mission highlights. Photographs and videos from each mission are included, as well as diagrams of different spacecraft, and computer-generated animations of the Mir deorbit, collision, and flyaround. Additional documents include mission status reports, published documents, news releases, personal letters, and oral histories. The experiments carried out on Mir are described, highlighting combustion and fluid physics research, life in microgravity, and research of the development of the solar system. The focus on improving space technology and planning for the International Space Station is explained. The main features of the book itself include: (1) Training and Operations; (2) Long Duration Psychology; (3) Bilingual Blues; and (4) Earth Observations.

  3. H2O2 space shuttle APU

    Science.gov (United States)

    1975-01-01

    A cryogenic H2-O2 auxiliary power unit (APU) was developed and successfully demonstrated. It has potential application as a minimum weight alternate to the space shuttle baseline APU because of its (1) low specific propellant consumption and (2) heat sink capabilities that reduce the amount of expendable evaporants. A reference system was designed with the necessary heat exchangers, combustor, turbine-gearbox, valves, and electronic controls to provide 400 shp to two aircraft hydraulic pumps. Development testing was carried out first on the combustor and control valves. This was followed by development of the control subsystem including the controller, the hydrogen and oxygen control valves, the combustor, and a turbine simulator. The complete APU system was hot tested for 10 hr with ambient and cryogenic propellants. Demonstrated at 95 percent of design power was 2.25 lb/hp-hr. At 10 percent design power, specific propellant consumption was 4 lb/hp-hr with space simulated exhaust and 5.2 lb/hp-hr with ambient exhaust. A 10 percent specific propellant consumption improvement is possible with some seal modifications. It was demonstrated that APU power levels could be changed by several hundred horsepower in less than 100 msec without exceeding allowable turbine inlet temperatures or turbine speed.

  4. Shuttle-Data-Tape XML Translator

    Science.gov (United States)

    Barry, Matthew R.; Osborne, Richard N.

    2005-01-01

    JSDTImport is a computer program for translating native Shuttle Data Tape (SDT) files from American Standard Code for Information Interchange (ASCII) format into databases in other formats. JSDTImport solves the problem of organizing the SDT content, affording flexibility to enable users to choose how to store the information in a database to better support client and server applications. JSDTImport can be dynamically configured by use of a simple Extensible Markup Language (XML) file. JSDTImport uses this XML file to define how each record and field will be parsed, its layout and definition, and how the resulting database will be structured. JSDTImport also includes a client application programming interface (API) layer that provides abstraction for the data-querying process. The API enables a user to specify the search criteria to apply in gathering all the data relevant to a query. The API can be used to organize the SDT content and translate into a native XML database. The XML format is structured into efficient sections, enabling excellent query performance by use of the XPath query language. Optionally, the content can be translated into a Structured Query Language (SQL) database for fast, reliable SQL queries on standard database server computers.

  5. Space shuttle heat pipe thermal control systems

    Science.gov (United States)

    Alario, J.

    1973-01-01

    Heat pipe (HP) thermal control systems designed for possible space shuttle applications were built and tested under this program. They are: (1) a HP augmented cold rail, (2) a HP/phase change material (PCM) modular heat sink and (3) a HP radiating panel for compartment temperature control. The HP augmented cold rail is similar to a standard two-passage fluid cold rail except that it contains an integral, centrally located HP throughout its length. The central HP core helps to increase the local power density capability by spreading concentrated heat inputs over the entire rail. The HP/PCM modular heat sink system consists of a diode HP connected in series to a standard HP that has a PCM canister attached to its mid-section. It is designed to connect a heat source to a structural heat sink during normal operation, and to automatically decouple from it and sink to the PCM whenever structural temperatures are too high. The HP radiating panel is designed to conductively couple the panel feeder HPs directly to a fluid line that serves as a source of waste heat. It is a simple strap-on type of system that requires no internal or external line modifications to distribute the heat to a large radiating area.

  6. Space shuttle SRM field joint: Review paper

    Directory of Open Access Journals (Sweden)

    S. Mohammad Gharouni

    2014-09-01

    Full Text Available Due to Challenger space shuttle accident in 1986, significant research has been done concerning structural behavior of field joints in solid rocket boosters (SRB. The structural deformations between the clevis inner leg and the tang (male-to-female parts of joint, the sealing of the O-ring to prevent the hot gas in joints, has been neglected causing the failure of the vehicle. Redesigning the field joint in SRB engine by accurate analysis of dynamic and thermal loads and by design of insulator and good O-ring, the leakiness of combustion hot gases was eliminated. Some parts of field joint such as capture feature (CF and its third O-ring, J-leg insulator and shim were added to redesigned field joint. Also, some adjustments in sealing system and pins were done to promote the efficiency of the field joint. Due to different experimental analysis on assembled field joints with default imperfections, redesigned joints operated well. These redesigned field joints are commonly used in aerospace and mechanical structures. This paper investigates the original and the redesigned field joints with additional explanations of different parts of the redesigned joints.

  7. IMPORTANT NOTICE: Cancellation of shuttle Circuit 3

    CERN Document Server

    2013-01-01

    Circuit 3 of the CERN Shuttle Service (Point 5), which has served CMS since the start of LS1, will be cancelled with effect from Tuesday 16 April. This decision has been taken in consultation with CMS, as the circuit was seldom used.   In response to increasing demand for Circuit 1 - Meyrin and feedback from passengers, the two Circuit 3 journeys will be switched to Circuit 1 – Meyrin (see new timetable below): Mornings: Four journeys instead of three. Circuit 1 now starts at 8:10 (instead of 8:19 a.m.) and runs until 9:27 a.m. (instead of 9:16 a.m.). Lunchtimes: Five journeys in place between 12:10 p.m. and 1:47 p.m. Evenings: Circuit starts at 5:23 p.m. (instead of 5:03 p.m.) and ends at 6:20 p.m. at Building 33. Please note that the circuit will depart from Building 13 instead of Building 33.  

  8. Sustainable Scientists

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Evan

    2008-12-31

    Scientists are front and center in quantifying and solving environmental problems. Yet, as a spate of recent news articles in scientific journals point out, much can be done to enhance sustainability within the scientific enterprise itself, particularly by trimming the energy use associated with research facilities and the equipment therein (i,ii,iii, iv). Sponsors of research unwittingly spend on the order of $10 billion each year on energy in the U.S. alone, and the underlying inefficiencies drain funds from the research enterprise while causing 80 MT CO2-equivalent greenhouse-gas emissions (see Box). These are significant sums considering the opportunity costs in terms of the amount of additional research that could be funded and emissions that could be reduced if the underlying energy was used more efficiently. By following commercially proven best practices in facility design and operation, scientists--and the sponsors of science--can cost-effectively halve these costs, while doing their part to put society on alow-carbon diet.

  9. Proton aurora and substorm intensifications

    Energy Technology Data Exchange (ETDEWEB)

    Samson, J.C.; Xu, B.; Lyons, L.R.; Newell, P.T.; Creutzberg, F.

    1993-10-01

    Ground based measurements from the CANOPUS array of meridian scanning photometers and precipitating ion and electron data from the DMSP F9 satellite show that the electron arc which brightens to initiate substorm intensifications is formed within a region of intense proton precipitation that is well equatorward (approximately four to six degrees) of the nightside open-closed field line boundary. The precipitating protons are from a population that is energized via earthward convection from the magnetotail into the dipolar region of the magnetosphere and may play an important role in the formation of the electron arcs leading to substorm intensifications on dipole-like field lines.

  10. Proton aurora and substorm intensifications

    Energy Technology Data Exchange (ETDEWEB)

    Samson, J.C.; Lyons, L.R.; Newell, P.T.; Creutzberg, F.; Xu, B. (Alberta Univ., Edmonton (Canada) Aerospace Corp., Space and Environmental Technology Center, Los Angeles, CA (United States) Johns Hopkins Univ., Laurel, MD (United States) National Research Council of Canada, Herzberg Inst. of Astrophysics, Ottawa (Canada) Canadian Network for Space Research, Edmonton (Canada))

    1992-11-01

    Ground based measurements from the CANOPUS array of meridian scanning photometers and precipitating ion and electron data from the DMSP F9 satellite show that the electron arc which brightens to initiate substorms intensifications is formed within a region of intense proton precipitation that is well equatorward (about 4-6 deg) of the nightside open-closed field line boundary. The precipitating protons are from a population that is energized via Earthward convection from the magnetotail into the dipolar region of the magnetosphere and may play an important role in the formation of the electron arcs leading to substorm intensifications on dipolelike field lines. 12 refs.

  11. Proton exchange membrane fuel cells

    CERN Document Server

    Qi, Zhigang

    2013-01-01

    Preface Proton Exchange Membrane Fuel CellsFuel CellsTypes of Fuel CellsAdvantages of Fuel CellsProton Exchange Membrane Fuel CellsMembraneCatalystCatalyst LayerGas Diffusion MediumMicroporous LayerMembrane Electrode AssemblyPlateSingle CellStackSystemCell Voltage Monitoring Module (CVM)Fuel Supply Module (FSM)Air Supply Module (ASM)Exhaust Management Module (EMM)Heat Management Module (HMM)Water Management Module (WMM)Internal Power Supply Module (IPM)Power Conditioning Module (PCM)Communications Module (COM)Controls Module (CM)SummaryThermodynamics and KineticsTheoretical EfficiencyVoltagePo

  12. Proton-antiproton collider physics

    CERN Document Server

    Altarelli, Guido

    1989-01-01

    This volume reviews the physics studied at the CERN proton-antiproton collider during its first phase of operation, from the first physics run in 1981 to the last one at the end of 1985. The volume consists of a series of review articles written by physicists who are actively involved with the collider research program. The first article describes the proton-antiproton collider facility itself, including the antiproton source and its principle of operation based on stochastic cooling. The subsequent six articles deal with the various physics subjects studied at the collider. Each article descr

  13. Sustainable agriculture - selected papers

    OpenAIRE

    Krasowicz, Stanisław; Wrzaszcz, Wioletta; Zegar, Jozef St.

    2007-01-01

    The concept of research on socially sustainable agriculture. Features of sustainable agriculture. Sustainability of private farms in the light of selected criteria. Subsistence agricultural holdings and the sustainable development of agriculture. Sustainable farms in the light of the FADN data. Description of organic holdings in Poland.

  14. Search for Sphalerons in Proton-Proton Collisions

    CERN Document Server

    Ellis, John

    2016-04-14

    In a recent paper, Tye and Wong (TW) have argued that sphaleron-induced transitions in high-energy proton-proton collisions should be enhanced compared to previous calculations, based on a construction of a Bloch wave function in the periodic sphaleron potential and the corresponding pass band structure. Here we convolute the calculations of TW with parton distribution functions and simulations of final states to explore the signatures of sphaleron transitions at the LHC and possible future colliders. We calculate the increase of sphaleron transition rates in proton-proton collisions at centre-of-mass energies of 13/14/33/100 TeV for different sphaleron barrier heights, while recognising that the rates have large overall uncertainties. We use a simulation to show that LHC searches for microscopic black holes should have good efficiency for detecting sphaleron-induced final states, and discuss their experimental signatures and observability in Run 2 of the LHC and beyond. We recast the early ATLAS Run-2 search...

  15. Proton beam therapy how protons are revolutionizing cancer treatment

    CERN Document Server

    Yajnik, Santosh

    2013-01-01

    Proton beam therapy is an emerging technology with promise of revolutionizing the treatment of cancer. While nearly half of all patients diagnosed with cancer in the US receive radiation therapy, the majority is delivered via electron accelerators, where photons are used to irradiate cancerous tissue. Because of the physical properties of photon beams, photons may deposit energy along their entire path length through the body. On the other hand, a proton beam directed at a tumor travels in a straight trajectory towards its target, gives off most of its energy at a defined depth called the Bragg peak, and then stops. While photons often deposit more energy within the healthy tissues of the body than within the cancer itself, protons can deposit most of their cancer-killing energy within the area of the tumor. As a result, in the properly selected patients, proton beam therapy has the ability to improve cure rates by increasing the dose delivered to the tumor and simultaneously reduce side-effects by decreasing...

  16. Concerted hydrogen-bond dynamics in the transport mechanism of the hydrated proton: a first-principles molecular dynamics study.

    Science.gov (United States)

    Berkelbach, Timothy C; Lee, Hee-Seung; Tuckerman, Mark E

    2009-12-04

    First-principles molecular dynamics calculations performed in a fully converged basis set are used to reveal new details about the mechanism of the anomalous proton-transport process in water, a fundamental question dating back over 200 years. By separating actual structural diffusion from simple rattling events, wherein a proton shuttles forth and back in a hydrogen bond, it is found that the former are driven by a concerted mechanism in which hydronium begins to accept a hydrogen bond from a donor water molecule while the proton-receiving water molecule simultaneously loses one of its acceptor hydrogen bonds. The kinetics of the process are found to be in good agreement with recent experiments.

  17. Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

    Energy Technology Data Exchange (ETDEWEB)

    Henry, Rowan M; Caplan, David; Pomes, Regis [Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, M5G 1X8 (Canada); Fadda, Elisa, E-mail: pomes@sickkids.ca [Department of Chemistry, University of Galway (Ireland)

    2011-06-15

    Cytochrome c oxidase, the terminal enzyme of the respiratory chain, utilizes the reduction of dioxygen into water to pump protons across the mitochondrial inner membrane. The principal pathway of proton uptake into the enzyme, the D channel, is a 2.5 nm long channel-like cavity named after a conserved, negatively charged aspartic acid (D) residue thought to help recruiting protons to its entrance (D132 in the first subunit of the S. sphaeroides enzyme). The single-point mutation of D132 to asparagine (N), a neutral residue, abolishes enzyme activity. Conversely, replacing conserved N139, one-third into the D channel, by D, induces a decoupled phenotype, whereby oxygen reduction proceeds but not proton pumping. Intriguingly, the double mutant D132N/N139D, which conserves the charge of the D channel, restores the wild-type phenotype. We use molecular dynamics simulations and electrostatic calculations to examine the structural and physical basis for the coupling of proton pumping and oxygen chemistry in single and double N139D mutants. The potential of mean force for the conformational isomerization of N139 and N139D side chains reveals the presence of three rotamers, one of which faces the channel entrance. This out-facing conformer is metastable in the wild-type and in the N139D single mutant, but predominant in the double mutant thanks to the loss of electrostatic repulsion with the carboxylate group of D132. The effects of mutations and conformational isomerization on the pKa of E286, an essential proton-shuttling residue located at the top of the D channel, are shown to be consistent with the electrostatic control of proton pumping proposed recently (Fadda et al 2008 Biochim. Biophys. Acta 1777 277-84). Taken together, these results suggest that preserving the spatial distribution of charges at the entrance of the D channel is necessary to guarantee both the uptake and the relay of protons to the active site of the enzyme. These findings highlight the interplay

  18. Sustainable NREL - Site Sustainability Plan FY 2015

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-01-01

    NREL's Site Sustainability Plan FY 2015 reports on sustainability plans for the lab for the year 2015 based on Executive Order Goals and provides the status on planned actions cited in the FY 2014 report.

  19. Study of space shuttle environmental control and life support problems

    Science.gov (United States)

    Dibble, K. P.; Riley, F. E.

    1971-01-01

    Four problem areas were treated: (1) cargo module environmental control and life support systems; (2) space shuttle/space station interfaces; (3) thermal control considerations for payloads; and (4) feasibility of improving system reusability.

  20. Vibroacoustic testing of Space Shuttle thermal protection system panels

    Science.gov (United States)

    Rucker, C. E.; Mixson, J. S.

    1976-01-01

    The modes and acoustic responses of two panels representing Space Shuttle thermal protection panels were investigated. The panels consisted of flat aluminum sheet stiffened longitudinally with hat-section stringers and corrugated supporting panels representing Shuttle ring frame bulkheads. In addition, one panel had 24 tiles of LI900 silica thermal insulation material and a strain isolator pad bonded to the face sheet. Both panels were found to have approximately eight modal frequencies in the 60 to 500 Hz range, where Shuttle acoustic loads are expected to be high. The strain response to a progressive acoustic wave representing a Shuttle spectrum was characterized by the occurrence of larger strains in the direction normal to the stringers than in the direction parallel to the stringers; three modes in the 100 to 400 Hz range contributed significantly to the strain response.

  1. Time-resolved vibrational spectroscopy of a molecular shuttle.

    Science.gov (United States)

    Panman, Matthijs R; Bodis, Pavol; Shaw, Danny J; Bakker, Bert H; Newton, Arthur C; Kay, Euan R; Leigh, David A; Buma, Wybren Jan; Brouwer, Albert M; Woutersen, Sander

    2012-02-14

    Time-resolved vibrational spectroscopy is used to investigate the inter-component motion of an ultraviolet-triggered two-station molecular shuttle. The operation cycle of this molecular shuttle involves several intermediate species, which are observable in the amide I and amide II regions of the mid-IR spectrum. Using ab initio calculations on specific parts of the rotaxane, and by comparing the transient spectra of the normal rotaxane with that of the N-deuterated version, we can assign the observed vibrational modes of each species occurring during the shuttling cycle in an unambiguous way. The complete time- and frequency-dependent data set is analyzed using singular value decomposition (SVD). Using a kinetic model to describe the time-dependent concentrations of the transient species, we derive the absorption spectra associated with each stage in the operation cycle of the molecular shuttle, including the recombination of the charged species.

  2. Mississippi National River and Recreation Area : shuttle market analysis

    Science.gov (United States)

    2015-05-05

    This report summarizes the results of marketing interviews conducted with National Park Service units operating shuttle services similar to what is being considered for the Mississippi National River and Recreation Area. The report includes lessons l...

  3. JSC amateur radio enthusiasts view video transmission to Shuttle

    Science.gov (United States)

    1985-01-01

    JSC amateur radio enthusiasts and the wives of shuttle astronauts Gordon Fullerton and Anthony England look at monitors showing the faces of the astronauts' wives which were transmitted from earth to space.

  4. Space Shuttle Main Propulsion System Anomaly Detection: A Case Study

    Data.gov (United States)

    National Aeronautics and Space Administration — The space shuttle main engine (SSME) is part of the Main Propnlsion System (MPS) which is an extremely complex system containing several sub-systems and components,...

  5. Catalytic Production of Olefin Block Copolymers via Chain Shuttling Polymerization

    National Research Council Canada - National Science Library

    Daniel J. Arriola; Edmund M. Carnahan; Phillip D. Hustad; Roger L. Kuhlman; Timothy T. Wenzel

    2006-01-01

    ...-olefin to ethylene in the two types of blocks. The system uses a chain shuttling agent to transfer growing chains between two distinct catalysts with different monomer selectivities in a single polymerization reactor...

  6. Analysis of the accuracy of Shuttle Radar Topography Mission ...

    Indian Academy of Sciences (India)

    DTM; SRTM. Abstract. The Shuttle Radar Topography Mission (SRTM) carried out in February 2000 has provided near global topographic data that has been widely used in many fields of earth sciences. The mission goal of an absolute vertical ...

  7. Space Shuttle Mission 41-C Official crew photo

    Science.gov (United States)

    1983-01-01

    Space Shuttle Mission 41-C Official crew photo. From left to right: Robert Crippen, crew commander; Terry Hart, mission specialist; James van Hoften, mission specialist; George Nelson, mission specialist; and Francis (Dick) Scobee, pilot.

  8. Quarkonium production in high energy proton-proton and proton-nucleus collisions

    CERN Document Server

    Conesa del Valle, Z; Fleuret, F; Ferreiro, E G; Kartvelishvili, V; Kopeliovich, B Z; Lansberg, J P; Lourenço, C; Martinez, G; Papadimitriou, V; Satz, H; Scomparin, E; Ullrich, T; Teryaev, O; Vogt, R; Wang, J X

    2011-01-01

    We present a brief overview of the most relevant current issues related to quarkonium production in high energy proton-proton and proton-nucleus collisions along with some perspectives. After reviewing recent experimental and theoretical results on quarkonium production in pp and pA collisions, we discuss the emerging field of polarisation studies. Thereafter, we report on issues related to heavy-quark production, both in pp and pA collisions, complemented by AA collisions. To put the work in a broader perspective, we emphasize the need for new observables to investigate quarkonium production mechanisms and reiterate the qualities that make quarkonia a unique tool for many investigations in particle and nuclear physics.

  9. Quarkonium production in high energy proton-proton and proton-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Conesa del Valle, Z. [Institut Pluridisciplinaire Hubert Curien (IPHC), Universite de Strasbourg, CNRS-IN2P3, Strasbourg (France); European Organization for Nuclear Research (CERN), Geneva (Switzerland); Corcella, G. [INFN, Laboratori Nazionali di Frascati, Via E.Fermi 40, I-00044, Frascati (Italy); Fleuret, F. [LLR, Ecole polytechnique, CNRS/IN2P3, Palaiseau (France); Ferreiro, E.G. [Departamento de Fisica de Particulas and IGFAE, Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Kartvelishvili, V. [Lancaster University, Lancaster LA1 4YB,United Kingdom (United Kingdom); Kopeliovich, B. [Departamento de Fisica Universidad Tecnica Federico Santa Maria, Instituto de Estudios Avanzados en Ciencias e Ingenieria and Centro, Cientifico-Tecnologico de Valparaiso, Casilla 110-V, Valparaiso (Chile); Lansberg, J.P. [IPNO, Universite Paris-Sud 11, CNRS/IN2P3, F-91406 Orsay (France); Lourenco, C. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Martinez, G. [SUBATECH, Ecole des Mines de Nantes, Universite de Nantes, CNRS-IN2P3, Nantes (France); Papadimitriou, V. [Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, Illinois, 60510, U.S.A (United States); Satz, H. [Fakultaet fuer Physik, Universitaet Bielefeld (Germany); Scomparin, E. [INFN Torino, Via P. Giuria 1, Torino, I-10125 (Italy); Ullrich, T. [Brookhaven National Laboratory, Upton, New York 11973 (United States); Teryaev, O. [Bogoliubov Laboratory of Theoretical Physics, JINR, Dubna 141980 (Russian Federation); Vogt, R. [Physics Divsion, Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States); Physics Department, University of California at Davis, Davis, CA 95616 (United States); Wang, J.X. [Institute of High Energy Physics, Chinese Academy of Sciences, P.O. Box 918(4), Beijing, 100049 (China)

    2011-05-15

    We present a brief overview of the most relevant current issues related to quarkonium production in high energy proton-proton and proton-nucleus collisions along with some perspectives. After reviewing recent experimental and theoretical results on quarkonium production in pp and pA collisions, we discuss the emerging field of polarisation studies. Afterwards, we report on issues related to heavy-quark production, both in pp and pA collisions, complemented by AA collisions. To put the work in broader perpectives, we emphasize the need for new observables to investigate the quarkonium production mechanisms and reiterate the qualities that make quarkonia a unique tool for many investigations in particle and nuclear physics.

  10. ASACUSA Anti-protonic Helium_Final

    CERN Multimedia

    CERN Audiovisual Production Service; CERN AD; Paola Catapano; Julien Ordan, Arzur Catel; Paola Catapano; ASACUSA COLLABORATION

    2016-01-01

    Latest precision measurement of the mass of the proton and the anti proton though the production of antiprotonic helium by the ASACUSA experiment at CERN's antimatter factory, with a beam from the Antiproton Decelerator

  11. Determining the mechanism of cusp proton aurora.

    Science.gov (United States)

    Xiao, Fuliang; Zong, Qiugang; Su, Zhenpeng; Yang, Chang; He, Zhaoguo; Wang, Yongfu; Gao, Zhonglei

    2013-01-01

    Earth's cusp proton aurora occurs near the prenoon and is primarily produced by the precipitation of solar energetic (2-10 keV) protons. Cusp auroral precipitation provides a direct source of energy for the high-latitude dayside upper atmosphere, contributing to chemical composition change and global climate variability. Previous studies have indicated that magnetic reconnection allows solar energetic protons to cross the magnetopause and enter the cusp region, producing cusp auroral precipitation. However, energetic protons are easily trapped in the cusp region due to a minimum magnetic field existing there. Hence, the mechanism of cusp proton aurora has remained a significant challenge for tens of years. Based on the satellite data and calculations of diffusion equation, we demonstrate that EMIC waves can yield the trapped proton scattering that causes cusp proton aurora. This moves forward a step toward identifying the generation mechanism of cusp proton aurora.

  12. Polarized protons and parity violating asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Trueman, T.L.

    1984-01-01

    The potential for utilizing parity violating effects, associated with polarized protons, to study the standard model, proton structure, and new physics at the SPS Collider is summarized. 24 references.

  13. Identifying involvement of Lys251/Asp252 pair in electron transfer and associated proton transfer at the quinone reduction site of Rhodobacter capsulatus cytochrome bc1.

    Science.gov (United States)

    Kuleta, Patryk; Sarewicz, Marcin; Postila, Pekka; Róg, Tomasz; Osyczka, Artur

    2016-10-01

    Describing dynamics of proton transfers in proteins is challenging, but crucial for understanding processes which use them for biological functions. In cytochrome bc1, one of the key enzymes of respiration or photosynthesis, proton transfers engage in oxidation of quinol (QH2) and reduction of quinone (Q) taking place at two distinct catalytic sites. Here we evaluated by site-directed mutagenesis the contribution of Lys251/Asp252 pair (bacterial numbering) in electron transfers and associated with it proton uptake to the quinone reduction site (Qi site). We showed that the absence of protonable group at position 251 or 252 significantly changes the equilibrium levels of electronic reactions including the Qi-site mediated oxidation of heme bH, reverse reduction of heme bH by quinol and heme bH/Qi semiquinone equilibrium. This implicates the role of H-bonding network in binding of quinone/semiquinone and defining thermodynamic properties of Q/SQ/QH2 triad. The Lys251/Asp252 proton path is disabled only when both protonable groups are removed. With just one protonable residue from this pair, the entrance of protons to the catalytic site is sustained, albeit at lower rates, indicating that protons can travel through parallel routes, possibly involving water molecules. This shows that proton paths display engineering tolerance for change as long as all the elements available for functional cooperation secure efficient proton delivery to the catalytic site. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  14. Smart drugs: green shuttle or real drug?

    Science.gov (United States)

    Cornara, L; Borghesi, B; Canali, C; Andrenacci, M; Basso, M; Federici, S; Labra, M

    2013-11-01

    We have combined morphological, molecular, and chemical techniques in order to identify the plant and chemical composition of some last-generation smart drugs, present on the market under the following names: Jungle Mistic Incense, B-52, Blendz, and Kratom 10x. Micromorphological analyses of botanical fragments allowed identification of epidermal cells, stomata, trichomes, starch, crystals, and pollen. DNA barcoding was carried out by the plastidial gene rbcL and the spacer trnH-psbA as universal markers. The combination of morphological and molecular data revealed a mixture of plants from different families, including aromatic species, viz., Lamiaceae and Turneraceae. GC-MS and LC-MS analyses on ethanol or methanol extracts showed the presence of synthetic cannabinoids, including JWH-250 in Jungle, JWH-122 in B-52, and JWH-073 and JWH-018 in Blendz. In Kratom 10x, only the indole alkaloid mitragynine was detected. All the identified synthetic cannabinoids, apart from mitragynine, are under the restriction of law in Italy (TU 309/90). Synthetic cannabinoid crystals were also identified by scanning electron microscopy and energy dispersive X-ray spectroscopy, which also detected other foreign organic chemicals, probably preservatives or antimycotics. In Kratom only leaf fragments from Mitragyna speciosa, containing the alkaloid mitragynine, were found. In the remaining products, aromatic plant species have mainly the role of hiding synthetic cannabinoids, thus acting as a "green shuttle" rather than as real drugs. Such a multidisciplinary approach is proposed as a method for the identification of herbal blends of uncertain composition, which are widely marketed in "headshops" and on the Internet, and represent a serious hazard to public health.

  15. Latent Virus Reactivation in Space Shuttle Astronauts

    Science.gov (United States)

    Mehta, S. K.; Crucian, B. E.; Stowe, R. P.; Sams, C.; Castro, V. A.; Pierson, D. L.

    2011-01-01

    Latent virus reactivation was measured in 17 astronauts (16 male and 1 female) before, during, and after short-duration Space Shuttle missions. Blood, urine, and saliva samples were collected 2-4 months before launch, 10 days before launch (L-10), 2-3 hours after landing (R+0), 3 days after landing (R+14), and 120 days after landing (R+120). Epstein-Barr virus (EBV) DNA was measured in these samples by quantitative polymerase chain reaction. Varicella-zoster virus (VZV) DNA was measured in the 381 saliva samples and cytomegalovirus (CMV) DNA in the 66 urine samples collected from these subjects. Fourteen astronauts shed EBV DNA in 21% of their saliva samples before, during, and after flight, and 7 astronauts shed VZV in 7.4% of their samples during and after flight. It was interesting that shedding of both EBV and VZV increased during the flight phase relative to before or after flight. In the case of CMV, 32% of urine samples from 8 subjects contained DNA of this virus. In normal healthy control subjects, EBV shedding was found in 3% and VZV and CMV were found in less than 1% of the samples. The circadian rhythm of salivary cortisol measured before, during, and after space flight did not show any significant difference between flight phases. These data show that increased reactivation of latent herpes viruses may be associated with decreased immune system function, which has been reported in earlier studies as well as in these same subjects (data not reported here).

  16. Sustainability in Transport Planning

    DEFF Research Database (Denmark)

    Gudmundsson, Henrik; Greve, Carsten

    Contribution to session J: Joint University Sustainability Initiatives. This session will provide an inspiring overview of interdisciplinary research and teaching activities on sustainability bridging DTU, KU, and CBS, and introduce the joint collaboration Copenhagen Sustainability Initiative (COSI...

  17. Sustainability : Politics and governance

    NARCIS (Netherlands)

    Heinrichs, Harald; Biermann, Frank

    2016-01-01

    he article gives an overview of global sustainability policy and politics. It is shown how international policy making on sustainable development has progressed from environmental policy toward recent approaches of Earth system governance. Key challenges of international sustainability politics are

  18. Low-Energy Proton Testing Methodology

    Science.gov (United States)

    Pellish, Jonathan A.; Marshall, Paul W.; Heidel, David F.; Schwank, James R.; Shaneyfelt, Marty R.; Xapsos, M.A.; Ladbury, Raymond L.; LaBel, Kenneth A.; Berg, Melanie; Kim, Hak S.; hide

    2009-01-01

    Use of low-energy protons and high-energy light ions is becoming necessary to investigate current-generation SEU thresholds. Systematic errors can dominate measurements made with low-energy protons. Range and energy straggling contribute to systematic error. Low-energy proton testing is not a step-and-repeat process. Low-energy protons and high-energy light ions can be used to measure SEU cross section of single sensitive features; important for simulation.

  19. Textiles and clothing sustainability sustainable technologies

    CERN Document Server

    2017-01-01

    This is the first book to deal with the innovative technologies in the field of textiles and clothing sustainability. It details a number of sustainable and innovative technologies and highlights their implications in the clothing sector. There are currently various measures to achieve sustainability in the textiles and the clothing industry, including innovations in the manufacturing stage, which is the crux of this book.

  20. Dilepton and double-photon production in proton-proton scattering at 190 MeV

    NARCIS (Netherlands)

    Caplar, R.; Bacelar, J.C.S; Castelijns, R.J.J.; Ermisch, K.; Gasparic, I.; Harakeh, M.N.; Kalantar-Nayestanaki, N.; Kis, M.; Löhner, H.; Mahjour Shafiei, M.

    2004-01-01

    The first high-statistics measurement of dilepton and double-photon yields in proton-proton scattering below the pion threshold has been performed. The data obtained allow a detailed study of off-shell effects in the proton-proton interaction.

  1. TOTEM: The experiment to measure the total proton-proton cross section at LHC

    OpenAIRE

    Lami, Stefano

    2006-01-01

    The current large uncertainty on the extrapolation of the proton-proton total cross section at the LHC energy will be resolved by the precise measurement by the TOTEM experiment. Its accurate studies on the basic properties of proton-proton collisions at the maximum accelerator energy could provide a significant contribution to the understanding of cosmic ray physics.

  2. Playing with Protons CREATIONS Demonstrator

    CERN Multimedia

    Alexopoulos, Angelos

    2017-01-01

    This document describes Playing with Protons, a CMS education initiative that seeks to enhance teachers’ pedagogical practice with creative, hands-on methodologies through which 10-12 year old students can, in turn, get engaged effectively with science, technology and innovation.

  3. Proton irradiation for hepatocellular carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Matsuzaki, Yasushi; Chiba, Shunya [Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine; Tanaka, Naomi

    1999-02-01

    A curative effect of high dose proton irradiation for hepatoma was investigated. In cases of single nodular type HCC, radiation field was limited to tumor, and in cases of multi nodular type HCC, irradiation was also fractionated. An average dose of radiation was 4 Gy/time, average times were 16, and an average total dose was 72 Gy. Tumor size reduction rate at 6 months after proton irradiation (123 cases) was CR (17.9%), PR (52.0%), NC (29.3%) and PD (0.8%). And the reduction rate of tumor size in monotherapy cases was 100% (after 3 weeks), 96% (after 1 year) and 88% (after 2 years). The local control rate was 99.1% (after 1 year) and 91.4% (after 3-5 years). AFP value significantly decreased from 571.0{+-}1266.6 ng/ml before radiation to 145.4{+-}346.3 ng/ml after radiation (p<0.0005). The recurrence after radiation occurred more at outside of radiation field, significantly. Indication basis of proton irradiation was showed in this article. Because selective radiation is possible, the proton irradiation should be optimum therapy in specific carcinomas of deep organ. (K.H.)

  4. Emerging technologies in proton therapy

    NARCIS (Netherlands)

    Schippers, Jacobus M.; Lomax, Antony J.

    An increasing number of proton therapy facilities are being planned and built at hospital based centers. Most facilities are employing traditional dose delivery methods. A second generation of dose application techniques, based on pencil beam scanning, is slowly being introduced into the

  5. Proton pump inhibitors and gastroenteritis

    NARCIS (Netherlands)

    R.J. Hassing (Robert); A. Verbon (Annelies); H. de Visser (Herman); A. Hofman (Albert); B.H.Ch. Stricker (Bruno)

    2016-01-01

    textabstractAn association between proton pump inhibitor (PPI) therapy and bacterial gastroenteritis has been suggested as well as contradicted. The aim of this study was to examine the association between the use of PPIs and occurrence of bacterial gastroenteritis in the prospective Rotterdam

  6. High current polarized proton sources

    Energy Technology Data Exchange (ETDEWEB)

    Alessi, J.G.

    1988-01-01

    Polarized proton sources are now being used more frequently on linacs. In pulsed operation up to 10 mA of /rvec H//sup +/ and 0.4 mA of /rvec H//sup /minus// have been produced. The present status of these sources, and developments to reach even higher intensities, are reviewed. 39 refs., 1 tab.

  7. Proton radiation therapy in Canada

    Energy Technology Data Exchange (ETDEWEB)

    Grein, E.; Duzenli, C.; Pickles, T.; Ma, R.; Paton, K.; Kwa, W.; Harrison, R.; Blackmore, E. [BC Cancer Agency, Vancouver, British Columbia (Canada); TRIUMF, Vancouver, British Columbia (Canada)

    2002-04-01

    The development, commissioning, and implementation of the first Canadian Proton Radiation Therapy facility at TRIUMF in British Columbia is described. This was a collaborative project by the cyclotron physicists and staff at TRIUMF, the medical physicists and radiation oncologists of the Cancer Agency and the ocular oncology physicians of the Eye Care Center at Vancouver Hospital. (author)

  8. Brand-new signage for the CERN shuttles

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    If, after reading the title of this article, you're striving to remember what the signs for the CERN shuttles look like, then you just hit the nail on the head: we bet that only a few people can actually do so. In order to make it easier for CERN users to move around the CERN sites, a graphic restyling of the shuttle signage has been implemented. You will start to see the new timetables in the coming days.   Larisa Kuchina, a graphic designer in the Communication Group, restyled the shuttle signage to make it more visible and intelligible. “I was inspired by the very clear and user friendly interface of the Geneva Public Transport system (TPG)”, explains Larisa. “Each timetable will also include the corresponding shuttle route. We will soon introduce new road signs for shuttle stops to make sure they are visible from a distance”. There are currently four shuttle lines, serving 28,000 passengers since February 2010: two of them operate between Meyrin and Pr...

  9. A progressive shuttle run test to estimate maximal oxygen uptake.

    Science.gov (United States)

    Ramsbottom, R; Brewer, J; Williams, C

    1988-12-01

    The purpose of the present study was to examine the validity of using a 20 m progressive shuttle run test to estimate maximal oxygen uptake. Running ability was described as the final level attained on the shuttle run test and as time on a 5 km run. Maximal oxygen uptake (VO2 max) was determined directly for seventy-four volunteers (36 men, 38 women) who also completed the shuttle run test. Maximal oxygen uptake values were 58.5 +/- 7.0 and 47.4 +/- 6.1 ml.kg-1.min-1 for the men and women respectively (mean +/- SD, P less than 0.01). The levels attained on the shuttle run test were 12.6 +/- 1.5 (men) and 9.6 +/- 1.8 (women; P less than 0.01). The correlation between VO2 max and shuttle level was 0.92. The correlation between VO2 max and the 5 km run was -0.94 and the correlation between both field tests was -0.96. The results of this study suggest that a progressive shuttle run test provides a valid estimate of VO2 max and indicates 5 km running potential in active men and women.

  10. Proton Testing: Opportunities, Pitfalls and Puzzles

    Science.gov (United States)

    Ladbury, Raymond

    2017-01-01

    Although proton SEE testing can place constraints on some heavy-ion SEE susceptibilities, it is important to quantify residual risk that protons may not reveal all SEE susceptibilities in a system. We examine the relative strengths and limitations of proton and heavy-ion SEE testing and how these may be affected by technology scaling and high-Z materials in the device.

  11. Shrink-wrapping water to conduct protons

    Science.gov (United States)

    Shimizu, George K. H.

    2017-11-01

    For proton-conducting metal-organic frameworks (MOFs) to find application as the electrolyte in proton-exchange membrane fuel cells, materials with better stability and conductivity are required. Now, a structurally flexible MOF that is also highly stable is demonstrated to possess high proton conductivity over a range of humidities.

  12. Inhibition of hepatitis B virus replication with linear DNA sequences expressing antiviral micro-RNA shuttles

    Energy Technology Data Exchange (ETDEWEB)

    Chattopadhyay, Saket; Ely, Abdullah; Bloom, Kristie; Weinberg, Marc S. [Antiviral Gene Therapy Research Unit, University of the Witwatersrand (South Africa); Arbuthnot, Patrick, E-mail: Patrick.Arbuthnot@wits.ac.za [Antiviral Gene Therapy Research Unit, University of the Witwatersrand (South Africa)

    2009-11-20

    RNA interference (RNAi) may be harnessed to inhibit viral gene expression and this approach is being developed to counter chronic infection with hepatitis B virus (HBV). Compared to synthetic RNAi activators, DNA expression cassettes that generate silencing sequences have advantages of sustained efficacy and ease of propagation in plasmid DNA (pDNA). However, the large size of pDNAs and inclusion of sequences conferring antibiotic resistance and immunostimulation limit delivery efficiency and safety. To develop use of alternative DNA templates that may be applied for therapeutic gene silencing, we assessed the usefulness of PCR-generated linear expression cassettes that produce anti-HBV micro-RNA (miR) shuttles. We found that silencing of HBV markers of replication was efficient (>75%) in cell culture and in vivo. miR shuttles were processed to form anti-HBV guide strands and there was no evidence of induction of the interferon response. Modification of terminal sequences to include flanking human adenoviral type-5 inverted terminal repeats was easily achieved and did not compromise silencing efficacy. These linear DNA sequences should have utility in the development of gene silencing applications where modifications of terminal elements with elimination of potentially harmful and non-essential sequences are required.

  13. Pair angular correlations for pions, kaons and protons in proton-proton collisions in ALICE

    CERN Document Server

    Zaborowska, Anna

    2014-01-01

    This thesis presents the correlation functions in $\\Delta\\eta\\, \\Delta\\phi$ space for pairs of pions, kaons and protons. The studies were carried out on the set of proton-proton collisions at the centre-of-mass energy $\\sqrt{s}$ = 7 TeV, obtained in ALICE, A Large Ion Collider Experiment at CERN, the European Organization for Nuclear Research. The analysis was performed for two charge combinations (like-sign pairs and unlike-sign pairs) as well as for three multiplicity ranges. Angular correlations are a rich source of information about the elementary particles behaviour. They result in from the interplay of numerous effects, including resonances’ decays, Coulomb interactions and energy and momentum conservation. In case of identical particles quantum statistics needs to be taken into account. Moreover, particles differ in terms of quark content. Kaons, carrying the strange quark obey the strangeness conservation law. In the production of protons baryon number must be conserved. These features are reflected...

  14. Dielectron production in proton-proton collisions with ALICE

    CERN Document Server

    Koehler, Markus K

    Ultrarelativistic hadron collisions, such as delivered since a couple of years at the Large Hadron Collider (LHC), provide new insights into the properties of strongly interacting matter at high temperatures and densities, which is expected to have existed a few of a millionth seconds after the big bang. Electromagnetic probes, such as leptons and photons, are emitted during the entire collision. Since they do not undergo strong interactions, they reflect the entire evolution of the collision.\\\\ Pairs of leptons, so called dileptons, have the advantage compared to real photons, that they do not only carry momentum, but also have a non-zero invariant mass. The invariant mass spectrum of dileptons is a superposition of several components and allows to address different characteristics of the medium.\\\\ To understand dielectron production in heavy-ion collisions, reference measurements in proton-proton (pp) collisions are necessary. pp collisions reflect the vacuum contribution of the particles produced in heavy-...

  15. Proton-Proton Elastic Scattering Excitation Functions at Intermediate Energies

    Science.gov (United States)

    Albers, D.; Bisplinghoff, J.; Bollmann, R.; Büßer, K.; Cloth, P.; Daniel, R.; Diehl, O.; Dohrmann, F.; Engelhardt, H. P.; Ernst, J.; Eversheim, P. D.; Gasthuber, M.; Gebel, R.; Greiff, J.; Groß, A.; Groß-Hardt, R.; Heider, S.; Heine, A.; Hinterberger, F.; Igelbrink, M.; Jahn, R.; Jeske, M.; Lahr, U.; Langkau, R.; Lindlein, J.; Maier, R.; Maschuw, R.; Mayer-Kuckuk, T.; Mosel, F.; Müller, M.; Münstermann, M.; Prasuhn, D.; Rohdjeß, H.; Rosendaal, D.; Roß, U.; von Rossen, P.; Scheid, H.; Schirm, N.; Schulz-Rojahn, M.; Schwandt, F.; Schwarz, V.; Scobel, W.; Sterzenbach, G.; Trelle, H. J.; Wellinghausen, A.; Wiedmann, W.; Woller, K.; Ziegler, R.

    1997-03-01

    Excitation functions of proton-proton elastic scattering cross sections have been measured in narrow steps for projectile momenta pp (energies Tp) from 1100 to 3300 MeV/c (500 to 2500 MeV) in the angular range 35°<=Θc.m.<=90° with a detector providing ΔΘc.m.~1.4° resolution. Measurements have been performed continuously during projectile acceleration in the cooler synchrotron COSY with an internal CH2 fiber target, taking particular care to monitor luminosity as a function of Tp. The advantages of this experimental technique are demonstrated, and the excitation functions obtained are compared to existing cross section data. No evidence for narrow structures was found.

  16. Proton-Proton Elastic Scattering Excitation Functions at Intermediate Energies

    Energy Technology Data Exchange (ETDEWEB)

    Bisplinghoff, J.; Daniel, R.; Diehl, O.; Engelhardt, H.; Ernst, J.; Eversheim, P.; Gro-Hardt, R.; Heider, S.; Heine, A.; Hinterberger, F.; Jahn, R.; Jeske, M.; Lahr, U.; Maschuw, R.; Mayer-Kuckuk, T.; Mosel, F.; Rohdje, H.; Rosendaal, D.; Ro, U.; Scheid, H.; Schulz-Rojahn, M.; Schwandt, F.; Schwarz, V.; Trelle, H.; Wiedmann, W.; Ziegler, R. [Inst.fuer Strahlen- und Kernphysik, Universitaet Bonn, D-53115 Bonn (Germany); Albers, D.; Bollmann, R.; Bueer, K.; Dohrmann, F.; Gasthuber, M.; Greiff, J.; Gro, A.; Igelbrink, M.; Langkau, R.; Lindlein, J.; Mueller, M.; Muenstermann, M.; Schirm, N.; Scobel, W.; Wellinghausen, A.; Woller, K. [I. Inst.fuer Experimentalphysik, Universitaet Hamburg, D-22761 Hamburg (Germany); Cloth, P.; Gebel, R.; Maier, R.; Prasuhn, D.; von Rossen, P.; Sterzenbach, G. [Inst.fuer Kernphysik, KFA Juelich, Juelich (Germany)

    1997-03-01

    Excitation functions of proton-proton elastic scattering cross sections have been measured in narrow steps for projectile momenta p{sub p} (energies T{sub p}) from 1100 to 3300MeV/c (500 to 2500MeV) in the angular range 35{degree}{le}{Theta}{sub c.m.}{le}90{degree} with a detector providing {Delta}{Theta}{sub c.m.}{approx}1.4{degree} resolution. Measurements have been performed continuously during projectile acceleration in the cooler synchrotron COSY with an internal CH{sub 2} fiber target, taking particular care to monitor luminosity as a function of T{sub p}. The advantages of this experimental technique are demonstrated, and the excitation functions obtained are compared to existing cross section data. No evidence for narrow structures was found. {copyright} {ital 1997} {ital The American Physical Society}

  17. Search for Sphalerons in Proton-Proton Collisions

    CERN Document Server

    Satco, Daria

    2017-01-01

    In view of new possibilities becoming more realistic with FCC design and of recent promising results regarding $(B+L)$-violating processes detection we concentrated our research on generation and analysis of sphaleron transitions. The existence of instanton and sphaleron solutions which are associated with transitions between different vacuum states is well known since 1980s. However first calculations of instanton rate killed any hope to detect them even at very high energies while the calculation of sphaleron transitions rate is a tricky problem which continue being widely discussed. In our research we used HERBVI package to generate baryon- and lepton-number violating processes in proton-proton collisions at typical energies 14, 33, 40 and 100 TeV in order to estimate the upper limit on the sphaleron cross-section. We considered the background processes and determined the zero background regions.

  18. Proton radiation damage in optical filter glass

    Science.gov (United States)

    Grillot, Patrick N.; Rosenberg, William J.

    1989-01-01

    Samples of Schott BG-39 and Hoya CM-500 blue-green filter glass were subjected to proton radiation to determine their acceptability for spaceflight. Initial testing done with 2.7 MeV protons showed negligible change in optical transmittance with doses as high as 5.2 x 10 to the 14th protons per sq cm. Irradiation with protons of energy up to 63 MeV caused a significant reduction in transmittance in the Schott samples at doses of 5.3 x 10 to the 12th protons per sq cm, while negligible change occurred in the Hoya samples.

  19. Proton conduction in biopolymer exopolysaccharide succinoglycan

    Energy Technology Data Exchange (ETDEWEB)

    Kweon, Jin Jung [Department of Physics, Korea University, Seoul 136-713 (Korea, Republic of); National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida 32310 (United States); Lee, Kyu Won; Kim, Hyojung; Lee, Cheol Eui, E-mail: rscel@korea.ac.kr [Department of Physics, Korea University, Seoul 136-713 (Korea, Republic of); Jung, Seunho [Department of Bioscience and Biotechnology and UBITA, Konkuk University, Seoul 143-701 (Korea, Republic of); Kwon, Chanho [Naraebio Research Laboratories, 177 Dangha-ri, Bongdam-eup, Hawseong-si 445-892 (Korea, Republic of)

    2014-07-07

    Protonic currents play a vital role in electrical signalling in living systems. It has been suggested that succinoglycan plays a specific role in alfalfa root nodule development, presumably acting as the signaling molecules. In this regard, charge transport and proton dynamics in the biopolymer exopolysaccharide succinoglycan have been studied by means of electrical measurements and nuclear magnetic resonance (NMR) spectroscopy. In particular, a dielectric dispersion in the system has revealed that the electrical conduction is protonic rather electronic. Besides, our laboratory- and rotating-frame {sup 1}H NMR measurements have elucidated the nature of the protonic conduction, activation of the protonic motion being associated with a glass transition.

  20. Microscopic dynamics of a base protonation

    Science.gov (United States)

    Knudsgaard, Bjørn; Petersen, Christian; Thøgersen, Jan; Keiding, Søren Rud; Jensen, Svend J. Knak

    2008-10-01

    The protonation of the base peroxynitrite in aqueous solution is investigated by way of the Car-Parrinello molecular dynamics technique. It is found that the protonation proceeds through an increase in the vibration amplitude of the hydrogen bond between the base and the hydronium ion. When the amplitude gets sufficiently large a proton may oscillate a few times between the base and the hydronium ion before it remains as part of peroxynitrous acid. The start of the protonation requires a certain orientation of the hydrogen bond. The estimated protonation time agrees well with the one obtained from femtosecond UV experiments.

  1. Loss of protons in thin absorbers

    CERN Document Server

    Renberg, P U; Measday, D F; Pepin, M; Serre, Claude; Schwaller, P

    1972-01-01

    Proton losses due to nuclear inelastic interactions have been measured in Al and Cu absorbers of thicknesses less than half the proton range, for incident proton energies of 250 and 560 MeV. It is shown that the data can be used to obtain absorption corrections in proton counter telescopes for other energies in this energy interval. The absorption correction would be found from the loss calculated from the proton reaction cross-sections by multiplying by an experimentally determined ratio which is given by the present measurement. (5 refs).

  2. An Opportunistic Wireless Charging System Design for an On-Demand Shuttle Service: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Doubleday, Kate; Meintz, Andrew; Markel, Tony

    2016-08-01

    System right-sizing is critical to implementation of in-motion wireless power transfer (WPT) for electric vehicles. This study introduces a modeling tool, WPTSim, which uses one-second speed, location, and road grade data from an on-demand employee shuttle in operation to simulate the incorporation of WPT at fine granularity. Vehicle power and state of charge are simulated over the drive cycle to evaluate potential system designs. The required battery capacity is determined based on the rated power at a variable number of charging locations. Adding just one WPT location can more than halve the battery capacity needed. Many configurations are capable of being self sustaining with WPT, while others benefit from supplemental stationary charging.

  3. Principles and practice of proton beam therapy

    CERN Document Server

    Das, Indra J

    2015-01-01

    Commissioned by The American Association of Physicists in Medicine (AAPM) for their June 2015 Summer School, this is the first AAPM monograph printed in full color. Proton therapy has been used in radiation therapy for over 70 years, but within the last decade its use in clinics has grown exponentially. This book fills in the proton therapy gap by focusing on the physics of proton therapy, including beam production, proton interactions, biology, dosimetry, treatment planning, quality assurance, commissioning, motion management, and uncertainties. Chapters are written by the world's leading medical physicists who work at the pioneering proton treatment centers around the globe. They share their understandings after years of experience treating thousands of patients. Case studies involving specific cancer treatments show that there is some art to proton therapy as well as state-of-the-art science. Even though the focus lies on proton therapy, the content provided is also valuable to heavy charged particle th...

  4. Very energetic protons in Saturn's radiation belt

    Science.gov (United States)

    Fillius, W.; Mcilwain, C.

    1980-01-01

    Very energetic protons are trapped in the inner Saturnian radiation belt. The University of California at San Diego instrument on Pioneer 11 has definitely identified protons of energy greater than 80 MeV on channel M3 and has tentatively detected protons of energy greater than 600 MeV on channel C3. The spatial distribution of the protons is distinct from that of the trapped electrons, the main difference being that the protons are strongly absorbed by the innermost moons and that the electrons are not. The source strength for injecting protons by the decay of cosmic ray albedo neutrons generated in the rings of Saturn has been estimated. The required proton lifetime is approximately 20 years.

  5. Assessing sustainable remediation frameworks using sustainability principles.

    Science.gov (United States)

    Ridsdale, D Reanne; Noble, Bram F

    2016-12-15

    The remediation industry has grown exponentially in recent decades. International organizations of practitioners and remediation experts have developed several frameworks for integrating sustainability into remediation projects; however, there has been limited attention to how sustainability is approached and operationalized in sustainable remediation frameworks and practices - or whether sustainability plays any meaningful role at all in sustainable remediation. This paper examines how sustainability is represented in remediation frameworks and the guidance provided for practical application. Seven broad sustainability principles and review criteria are proposed and applied to a sample of six international remediation frameworks. Not all review criteria were equally satisfied and none of the frameworks fully met all criteria; however, the best performing frameworks were those identified as sustainability remediation frameworks. Intra-generational equity was addressed by all frameworks. Integrating social, economic and biophysical components beyond triple-bottom-line indicators was explicitly addressed only by the sustainable remediation frameworks. No frameworks provided principle- or rule-based guidance for dealing with trade-offs in sustainability decisions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Organizing for Sustainability

    Science.gov (United States)

    Brown, William M.; Hamburger, Michael W.

    2012-01-01

    A successful campus sustainability effort catalyzes broad engagement of the campus community and integration of sustainability principles into the academic and operational components of campus life. Although many universities have embraced sustainability as a new core value, others have been more sluggish in adopting sustainability principles to…

  7. Technology and sustainability

    NARCIS (Netherlands)

    Kroeze, C.; Boersema, J.J.; Tellegen, E.; Cremers, A.

    2011-01-01

    In ten essays, this book addresses a broad range of issues related to the interplay of sustainability and technology. How do population growth and technology relate to sustainable development? Can globalization be reconciled with sustainable development? Is sustainability a subjective or an

  8. Action Research for Sustainability

    DEFF Research Database (Denmark)

    Egmose, Jonas

    by analysing processes of social learning. The book addresses the need to move towards sustainability at societal level as a democratic challenge questioning the way we live on planet earth. By conceptualising sustain-ability as an immanent and emergent ability of ecological and social life, continuously...... to renew itself without eroding its own foundation of existence, it argues that since sustainability cannot be invented but only supported (or eroded) by science, we need to reframe science in the role of sustaining sustain-ability. Through analyses of a three year action research programme, aiming...

  9. Sustainable Investment. Literature Overview

    Energy Technology Data Exchange (ETDEWEB)

    Weda, J.; Kerste, M.; Rosenboom, N.

    2010-08-15

    Corporate Social Responsibility (CSR), or sustainability at the company level, entails incorporating ecological (environmental stakeholders) and social aspects (stakeholders other than shareholders and environmental stakeholders) when doing business. Socially Responsible Investment (SRI) concerns sustainability at the investment, fund or portfolio level and involves screening the sustainability of companies before investing in them. This report highlights leading literature and empirical findings on 'sustainable investment', amongst others addressing the economic rationale for CSR and SRI. This report is part of a set of SEO-reports on finance and sustainability. The other reports deal with: Financing the Transition to Sustainable Energy; Carbon Trading; Innovations in financing environmental and social sustainability.

  10. Proton Radiography at Los Alamos

    Energy Technology Data Exchange (ETDEWEB)

    Saunders, Alexander [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-28

    The proton radiography (pRad) facility at Los Alamos National Lab uses high energy protons to acquire multiple frame flash radiographic sequences at megahertz speeds: that is, it can make movies of the inside of explosions as they happen. The facility is primarily used to study the damage to and failure of metals subjected to the shock forces of high explosives as well as to study the detonation of the explosives themselves. Applications include improving our understanding of the underlying physical processes that drive the performance of the nuclear weapons in the United States stockpile and developing novel armor technologies in collaboration with the Army Research Lab. The principle and techniques of pRad will be described, and examples of some recent results will be shown.

  11. Proton affinities of hydrated molecules

    Science.gov (United States)

    Valadbeigi, Younes

    2016-09-01

    Proton affinities (PA) of non-hydrated, M, and hydrated forms, M(H2O)1,2,3, of 20 organic molecules including alcohols, ethers, aldehydes, ketones and amines were calculated by the B3LYP/6-311++G(d,p) method. For homogeneous families, linear correlations were observed between PAs of the M(H2O)1,2,3 and the PAs of the non-hydrated molecules. Also, the absolute values of the hydration enthalpies of the protonated molecules decreased linearly with the PAs. The correlation functions predicted that for an amine with PA amine with PA > 1100 kJ/mol the PA(M(H2O)) is smaller than the PA.

  12. DIMETHYL ETHER (DME)-FUELED SHUTTLE BUS DEMONSTRATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Elana M. Chapman; Shirish Bhide; Jennifer Stefanik; Howard Glunt; Andre L. Boehman; Allen Homan; David Klinikowski

    2003-04-01

    The objectives of this research and demonstration program are to convert a campus shuttle bus to operation on dimethyl ether, a potential ultra-clean alternative diesel fuel. To accomplish this objective, this project includes laboratory evaluation of a fuel conversion strategy, as well as, field demonstration of the DME-fueled shuttle bus. Since DME is a fuel with no lubricity (i.e., it does not possess the lubricating quality of diesel fuel), conventional fuel delivery and fuel injection systems are not compatible with dimethyl ether. Therefore, to operate a diesel engine on DME one must develop a fuel-tolerant injection system, or find a way to provide the necessary lubricity to the DME. In this project, they have chosen the latter strategy in order to achieve the objective with minimal need to modify the engine. Their strategy is to blend DME with diesel fuel, to obtain the necessary lubricity to protect the fuel injection system and to achieve low emissions. The bulk of the efforts over the past year were focused on the conversion of the campus shuttle bus. This process, started in August 2001, took until April 2002 to complete. The process culminated in an event to celebrate the launching of the shuttle bus on DME-diesel operation on April 19, 2002. The design of the system on the shuttle bus was patterned after the system developed in the engine laboratory, but also was subjected to a rigorous failure modes effects analysis (FMEA, referred to by Air Products as a ''HAZOP'' analysis) with help from Dr. James Hansel of Air Products. The result of this FMEA was the addition of layers of redundancy and over-pressure protection to the system on the shuttle bus. The system became operational in February 2002. Preliminary emissions tests and basic operation of the shuttle bus took place at the Pennsylvania Transportation Institute's test track facility near the University Park airport. After modification and optimization of the system on

  13. Proton Resonance Spectroscopy -- Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Shriner, Jr., J. F. [Tennessee Technological Univ., Cookeville, TN (United States)

    2009-07-27

    This report summarizes work supported by the DOE Grant DE-FG02-96ER40990 during its duration from June 1996 to May 2009. Topics studied include (1) statistical descriptions of nuclear levels and measurements of proton resonances relevant to such descriptions, including measurements toward a complete level scheme for 30P, (2) the development of methods to estimate the missing fraction of levels in a given measurement, and (3) measurements at HRIBF relevant to nuclear astrophysics.

  14. Proton Therapy for Thoracoabdominal Tumors

    Science.gov (United States)

    Sakurai, Hideyuki; Okumura, Toshiyuki; Sugahara, Shinji; Nakayama, Hidetsugu; Tokuuye, Koichi

    In advanced-stage disease of certain thoracoabdominal tumors, proton therapy (PT) with concurrent chemotherapy may be an option to reduce side effects. Several technological developments, including a respiratory gating system and implantation of fiducial markers for image guided radiation therapy (IGRT), are necessary for the treatment in thoracoabdominal tumors. In this chapter, the role of PT for tumors of the lung, the esophagus, and liver are discussed.

  15. Proton Pump Inhibitors and Gastritis

    OpenAIRE

    Suzuki, Masayuki; Suzuki, Hidekazu; Hibi, Toshifumi

    2008-01-01

    Proton pump inhibitors (PPIs) are novel compounds that strongly inhibit the H+/K+-ATPase in the gastric parietal cells to cause profound suppression of acid secretion. Acid-generating ATPase, also known as vacuolar-type ATPase, is located in the lysozomes of leukocytes and osteoclasts and its activity is also reportedly influenced by treatment with PPIs. This concept is supported by the results of studies using autoradiography in which 3H-Lansoprazole uptake sites were clearly detected in the...

  16. Modal Testing of Seven Shuttle Cargo Elements for Space Station

    Science.gov (United States)

    Kappus, Kathy O.; Driskill, Timothy C.; Parks, Russel A.; Patterson, Alan (Technical Monitor)

    2001-01-01

    From December 1996 to May 2001, the Modal and Control Dynamics Team at NASA's Marshall Space Flight Center (MSFC) conducted modal tests on seven large elements of the International Space Station. Each of these elements has been or will be launched as a Space Shuttle payload for transport to the International Space Station (ISS). Like other Shuttle payloads, modal testing of these elements was required for verification of the finite element models used in coupled loads analyses for launch and landing. The seven modal tests included three modules - Node, Laboratory, and Airlock, and four truss segments - P6, P3/P4, S1/P1, and P5. Each element was installed and tested in the Shuttle Payload Modal Test Bed at MSFC. This unique facility can accommodate any Shuttle cargo element for modal test qualification. Flexure assemblies were utilized at each Shuttle-to-payload interface to simulate a constrained boundary in the load carrying degrees of freedom. For each element, multiple-input, multiple-output burst random modal testing was the primary approach with controlled input sine sweeps for linearity assessments. The accelerometer channel counts ranged from 252 channels to 1251 channels. An overview of these tests, as well as some lessons learned, will be provided in this paper.

  17. Revised estimates for ozone reduction by shuttle operation

    Science.gov (United States)

    Potter, A. E.

    1978-01-01

    Previous calculations by five different modeling groups of the effect of space shuttle operations on the ozone layer yielded an estimate of 0.2 percent ozone reduction for the Northern Hemisphere at 60 launches per year. Since these calculations were made, the accepted rate constant for the reaction between hydroperoxyl and nitric oxide to yield hydroxyl and nitrogen dioxide, HO2 + NO yields OH + NO2, was revised upward by more than an order of magnitude, with a resultant increase in the predicted ozone reduction for chlorofluoromethanes by a factor of approximately 2. New calculations of the shuttle effect were made with use of the new rate constant data, again by five different modeling groups. The new value of the shuttle effect on the ozone layer was found to be 0.25 percent. The increase resulting from the revised rate constant is considerably less for space shuttle operations than for chlorofluoromethane production, because the new rate constant also increases the calculated rate of downward transport of shuttle exhaust products out of the stratosphere.

  18. STS-98 Space Shuttle Atlantis after RSS rollback

    Science.gov (United States)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. -- This closeup reveals Space Shuttle Atlantis after rollback of the Rotating Service Structure. Extended to the side of Atlantis is the orbiter access arm, with the White Room at its end. The White Room provides entry for the crew into Atlantis'''s cockpit. Below Atlantis, on either side of the tail, are the tail service masts. They support the fluid, gas and electrical requirements of the orbiter'''s liquid oxygen and liquid hydrogen aft T-0 umbilicals. Atlantis is carrying the U.S. Laboratory Destiny, a key module in the growth of the International Space Station. Destiny will be attached to the Unity node on the Space Station using the Shuttle'''s robotic arm. Three spacewalks are required to complete the planned construction work during the 11-day mission. Launch is targeted for 6:11 p.m. EST and the planned landing at KSC Feb. 18 about 1:39 p.m. This mission marks the seventh Shuttle flight to the Space Station, the 23rd flight of Atlantis and the 102nd flight overall in NASA'''s Space Shuttle program.

  19. High-Intensity Proton Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Jay L. Hirshfield

    2011-12-27

    Analysis is presented for an eight-cavity proton cyclotron accelerator that could have advantages as compared with other accelerators because of its potentially high acceleration gradient. The high gradient is possible since protons orbit in a sequence of TE111 rotating mode cavities of equally diminishing frequencies with path lengths during acceleration that greatly exceed the cavity lengths. As the cavities operate at sequential harmonics of a basic repetition frequency, phase synchronism can be maintained over a relatively wide injection phase window without undue beam emittance growth. It is shown that use of radial vanes can allow cavity designs with significantly smaller radii, as compared with simple cylindrical cavities. Preliminary beam transport studies show that acceptable extraction and focusing of a proton beam after cyclic motion in this accelerator should be possible. Progress is also reported on design and tests of a four-cavity electron counterpart accelerator for experiments to study effects on beam quality arising from variations injection phase window width. This device is powered by four 500-MW pulsed amplifiers at 1500, 1800, 2100, and 2400 MHz that provide phase synchronous outputs, since they are driven from a with harmonics derived from a phase-locked 300 MHz source.

  20. Solid-state proton conductors

    Energy Technology Data Exchange (ETDEWEB)

    Jewulski, J.R.; Osif, T.L.; Remick, R.J.

    1990-12-01

    The purpose of this program was to survey the field of solid-state proton conductors (SSPC), identify conductors that could be used to develop solid-state fuel cells suitable for use with coal derived fuel gases, and begin the experimental research required for the development of these fuel cells. This document covers the following topics: the history of developments and current status of the SSPC, including a review of proton conducting electrolyte structures, the current status of the medium temperature SSPC development, electrodes for moderate temperature (SSPC) fuel cell, basic material and measurement techniques applicable for SSPC development, modeling and optimization studies. Correlation and optimization studies, to include correlation studies on proton conduction and oxide cathode optimization for the SSPC fuel cell. Experiments with the SSPC fuel cells including the fabrication of the electrolyte disks, apparatus for conducting measurements, the strontium-cerium based electrolyte, the barium-cerium based electrolyte with solid foil electrodes, the barium-cerium based electrolyte with porous electrodes, and conduction mechanisms. 164 refs., 27 figs., 13 tabs.

  1. One-proton halo in 26P and two-proton halo in 27S

    Science.gov (United States)

    Ren, Zhongzhou; Chen, Baoqiu; Ma, Zhongyu; Xu, Gongou

    1996-02-01

    Proton-drip-line nuclei 26P and 27S are studied in the nonlinear relativistic mean-field theory. Calculations show that the mean-square radius of protons in the 2s1/2 state is approximately 18-20 fm2 which is abnormally large as compared with the mean-square radii of proton, neutron, and matter distributions, giving a strong evidence for proton halos in 26P and 27S. This indicates that the size of proton halos is as large as that of neutron halos although there exists the Coulomb barrier in proton-drip-line nuclei.

  2. Transport-Relevant Protein Conformational Dynamics and Water Dynamics on Multiple Timescales in an Archetypal Proton Channel - Insights from Solid-State NMR.

    Science.gov (United States)

    Mandala, Venkata; Gelenter, Martin D; Hong, Mei

    2018-01-05

    The influenza M2 protein forms a tetrameric proton channel that conducts protons from the acidic endosome into the virion by shuttling protons between water and a transmembrane histidine. Previous NMR studies have shown that this histidine protonates and deprotonates on the microsecond timescale. However, M2's proton conduction rate is 10 - 1000 s-1, more than two orders of magnitude slower than the histidine-water proton-exchange rate. M2 is also known to be conformationally plastic. To address the disparity between the functional timescale and the timescales of protein conformational dynamics and water dynamics, we have now investigated a W41F mutant of the M2 transmembrane domain using solid-state NMR. 13C chemical shifts of the membrane-bound peptide indicate the presence of two distinct tetramer conformations, whose concentrations depend exclusively on pH and hence the charge-state distribution of the tetramers. High-temperature 2D correlation spectra indicate that these two conformations interconvert at a rate of ~400 s-1 when the +2 and +3 charge states dominate, which gives the first experimental evidence of protein conformational motion on the transport timescale. Protein 13C-detected water 1H T2 relaxation measurements show that channel water relaxes an order of magnitude faster than bulk water and membrane-associated water, indicating that channel water undergoes nanosecond motion in a pH-independent fashion. These results connect motions on three timescales to explain M2's proton-conduction mechanism: picosecond-to-nanosecond motions of water molecules facilitate proton Grotthuss hopping, microsecond motions of the histidine sidechain allow water-histidine proton transfer, while millisecond motions of the entire four-helix bundle constitute the rate-limiting step, dictating the number of protons released into the virion.

  3. Space operations center: Shuttle interaction study extension, executive summary

    Science.gov (United States)

    1982-01-01

    The Space Operations Center (SOC) is conceived as a permanent facility in low Earth orbit incorporating capabilities for space systems construction; space vehicle assembly, launching, recovery and servicing; and the servicing of co-orbiting satellites. The Shuttle Transportation System is an integral element of the SOC concept. It will transport the various elements of the SOC into space and support the assembly operation. Subsequently, it will regularly service the SOC with crew rotations, crew supplies, construction materials, construction equipment and components, space vehicle elements, and propellants and spare parts. The implications to the SOC as a consequence of the Shuttle supporting operations are analyzed. Programmatic influences associated with propellant deliveries, spacecraft servicing, and total shuttle flight operations are addressed.

  4. Redox shuttles for overcharge protection of lithium batteries

    Science.gov (United States)

    Amine, Khalil; Chen, Zonghai; Wang, Qingzheng

    2010-12-14

    The present invention is generally related to electrolytes containing novel redox shuttles for overcharge protection of lithium-ion batteries. The redox shuttles are capable of thousands hours of overcharge tolerance and have a redox potential at about 3-5.5 V vs. Li and particularly about 4.4-4.8 V vs. Li. Accordingly, in one aspect the invention provides electrolytes comprising an alkali metal salt; a polar aprotic solvent; and a redox shuttle additive that is an aromatic compound having at least one aromatic ring with four or more electronegative substituents, two or more oxygen atoms bonded to the aromatic ring, and no hydrogen atoms bonded to the aromatic ring; and wherein the electrolyte solution is substantially non-aqueous. Further there are provided electrochemical devices employing the electrolyte and methods of making the electrolyte.

  5. Investigations of Shuttle Main Landing Gear Door Environmental Seals

    Science.gov (United States)

    Finkbeiner, Joshua; Dunlap, Pat; Steinetz, Bruce; DeMango, Jeff; Newswander, Daniel

    2005-01-01

    The environmental seals for the main landing gear doors of the Shuttle Orbiters were raised by the Columbia Accident Investigation Board as a potential safety concern. Inspections of seals installed on the Shuttle Discovery revealed that they were permanently deformed and no longer met certified seal compression requirements. Replacement of the seals led to the inability to fully close the main landing gear doors. Johnson Space Center requested that Glenn Research Center conduct tests on the main landing gear door environmental seals to assist in installing the seals in a manner to allow the main landing gear doors to fully close. Further testing was conducted to fill out the seal performance database. Results from the testing indicated that the method of bonding the seals was important in reducing seal loads on the main landing gear doors. Also, the replacement seals installed in Shuttle Discovery were found to have leakage performance sufficient to meet the certification requirements.

  6. Shuttle Planning for Link Closures in Urban Public Transport Networks

    DEFF Research Database (Denmark)

    van der Hurk, Evelien; Koutsopoulos, Haris N.; Wilson, Nigel

    2016-01-01

    cost, which includes transfers and frequency-dependent waiting time costs. This model is applied to a shuttle design problem based on a real-world case study of the Massachusetts Bay Transportation Authority network of Boston, Massachusetts. The results show that additional shuttle routes can reduce......Urban public transport systems must periodically close certain links for maintenance, which can have significant effects on the service provided to passengers. In practice, the effects of closures are mitigated by replacing the closed links with a simple shuttle service. However, alternative...... passenger delay compared to the standard industry practice, while also distributing delay more equally over passengers, at the same operating budget. The results are robust under different assumptions about passenger route choice behavior. Computational experiments show that the proposed formulation...

  7. NASDA aquatic animal experiment facilities for space shuttle and ISS

    Science.gov (United States)

    Uchida, Satoko; Masukawa, Mitsuyo; Kamigaichi, Shigeki

    National Space Development Agency of Japan (NASDA) has developed aquatic animal experiment facilities for NASA Space Shuttle use. Vestibular Function Experiment Unit (VFEU) was firstly designed and developed for physiological research using carp in Spacelab-J (SL-J, STS-47) mission. It was modified as Aquatic Animal Experiment Unit (AAEU) to accommodate small aquatic animals, such as medaka and newt, for second International Microgravity Laboratory (IML-2, STS-65) mission. Then, VFEU was improved to accommodate marine fish and to perform neurobiological experiment for Neurolab (STS-90) and STS-95 missions. We have also developed and used water purification system which was adapted to each facility. Based on these experiences of Space Shuttle missions, we are studying to develop advanced aquatic animal experiment facility for both Space Shuttle and International Space Station (ISS).

  8. Report of the Space Shuttle Management Independent Review Team

    Science.gov (United States)

    1995-01-01

    At the request of the NASA Administrator a team was formed to review the Space Shuttle Program and propose a new management system that could significantly reduce operating costs. Composed of a group of people with broad and extensive experience in spaceflight and related areas, the team received briefings from the NASA organizations and most of the supporting contractors involved in the Shuttle Program. In addition, a number of chief executives from the supporting contractors provided advice and suggestions. The team found that the present management system has functioned reasonably well despite its diffuse structure. The team also determined that the shuttle has become a mature and reliable system, and--in terms of a manned rocket-propelled space launch system--is about as safe as today's technology will provide. In addition, NASA has reduced shuttle operating costs by about 25 percent over the past 3 years. The program, however, remains in a quasi-development mode and yearly costs remain higher than required. Given the current NASA-contractor structure and incentives, it is difficult to establish cost reduction as a primary goal and implement changes to achieve efficiencies. As a result, the team sought to create a management structure and associated environment that enables and motivates the Program to further reduce operational costs. Accordingly, the review team concluded that the NASA Space Shuttle Program should (1) establish a clear set of program goals, placing a greater emphasis on cost-efficient operations and user-friendly payload integration; (2) redefine the management structure, separating development and operations and disengaging NASA from the daily operation of the space shuttle; and (3) provide the necessary environment and conditions within the program to pursue these goals.

  9. Action Research for Sustainability

    DEFF Research Database (Denmark)

    Egmose, Jonas

    How can action research further new research orientations towards sustainability? This book, empirically situated in the field of upstream public engagement, involving local residents, researchers and practitioners in bottom-up processes deliberating on urban sustainability, answers this question...... by analysing processes of social learning. The book addresses the need to move towards sustainability at societal level as a democratic challenge questioning the way we live on planet earth. By conceptualising sustain-ability as an immanent and emergent ability of ecological and social life, continuously...... to renew itself without eroding its own foundation of existence, it argues that since sustainability cannot be invented but only supported (or eroded) by science, we need to reframe science in the role of sustaining sustain-ability. Through analyses of a three year action research programme, aiming...

  10. Orbit transfer operations for the Space Shuttle era

    Science.gov (United States)

    Davis, H. P.

    1979-01-01

    Orbit transfer operations are reviewed relative to the objectives, operational factors, and crew model concepts of future mission requirements. The review is based on studies presently underway and on projected needs and goals of the Space Shuttle era. Numerous tradeoff studies and further analyses are needed before the best form of the manned geostationary vehicle becomes fixed. However, the Shuttle can provide the necessary low-orbit logistics service for dispatching manned geostationary missions on as frequent a schedule as will be needed to serve the advanced geostationary satellites of the near future.

  11. Space shuttle launch vehicle aerodynamic uncertainties: Lessons learned

    Science.gov (United States)

    Hamilton, J. T.

    1983-01-01

    The chronological development and evolution of an uncertainties model which defines the complex interdependency and interaction of the individual Space Shuttle element and component uncertainties for the launch vehicle are presented. Emphasis is placed on user requirements which dictated certain concessions, simplifications, and assumptions in the analytical model. The use of the uncertainty model in the vehicle design process and flight planning support is discussed. The terminology and justification associated with tolerances as opposed to variations are also presented. Comparisons of and conclusions drawn from flight minus predicted data and uncertainties are given. Lessons learned from the Space Shuttle program concerning aerodynamic uncertainties are examined.

  12. HAL/S programmer's guide. [for space shuttle program

    Science.gov (United States)

    Newbold, P. M.; Hotz, R. L.

    1974-01-01

    This programming language was developed for the flight software of the NASA space shuttle program. HAL/S is intended to satisfy virtually all of the flight software requirements of the space shuttle. To achieve this, HAL/s incorporates a wide range of features, including applications-oriented data types and organizations, real time control mechanisms, and constructs for systems programming tasks. As the name indicates, HAL/S is a dialect of the original HAL language previously developed. Changes have been incorporated to simplify syntax, curb excessive generality, or facilitate flight code emission.

  13. Space shuttle safety - A hybrid vehicle breeds new problems.

    Science.gov (United States)

    Pinkel, I. I.

    1971-01-01

    Discussion of a few novel problems raised by the design and flight plan of the space shuttle and by the dangerous cargos it might carry. Among the problems cited are those connected with the inspection of the bearings of the propellant turbopumps, particularly those of the hydrogen pump, for evidence of spalling, as well as problems arising in the inspection of the high-temperature parts of the combustor and turbine section of the airbreathing turbofan for shuttle booster and orbiter, and problems resulting from the possibility of fire hazard due to spontaneous ignition of fuel vapor in the fuel tank vapor space.

  14. New timetable for a Regular morning and evening shuttle

    CERN Multimedia

    TS Department

    2008-01-01

    Starting from 31 March 2008, for one month, a new timetable for a regular morning and evening shuttle serving LHC Points 2 and 5 will be put in place. You can find all the corresponding details on the FM group WEB page: http://ts-dep.web.cern.ch/ts-dep/groups/fm/logistique/shuttle_timetable.htm Please note that during April, all other requests for transport from Meyrin and Prévessin to the LHC Points via tel. 76969 during the day (between 8:30 and 17:30) will not be met. TS/FM group Tel. 160239

  15. New timetable for a morning and evening regular shuttle

    CERN Multimedia

    TS Department

    2008-01-01

    Starting from the 31st of March 2008 and for one month, a new timetable for a morning and evening regular shuttle serving LHC Points 2 and 5, will be put in place. You can find all the corresponding details in the FM group WEB page http://ts-dep.web.cern.ch/ts-dep/groups/fm/logistique/shuttle_timetable.htm Please note that during April, every other request of transfer from Meyrin and Prevessin towards LHC Points reaching the 76969 during the day (between 8:30 and 17:30) will not be satisfied. TS/FM group 160239

  16. Space Shuttle Orbiter logistics - Managing in a dynamic environment

    Science.gov (United States)

    Renfroe, Michael B.; Bradshaw, Kimberly

    1990-01-01

    The importance and methods of monitoring logistics vital signs, logistics data sources and acquisition, and converting data into useful management information are presented. With the launch and landing site for the Shuttle Orbiter project at the Kennedy Space Center now totally responsible for its own supportability posture, it is imperative that logistics resource requirements and management be continually monitored and reassessed. Detailed graphs and data concerning various aspects of logistics activities including objectives, inventory operating levels, customer environment, and data sources are provided. Finally, some lessons learned from the Shuttle Orbiter project and logistics options which should be considered by other space programs are discussed.

  17. Sustaining Rural Communities through Sustainable Agriculture.

    Science.gov (United States)

    Ikerd, John

    A 5-year collaborative project between Missouri, Michigan State, and Nebraska Universities to provide new opportunities for rural community self-development through sustainable agriculture had mixed results. This happened because community members did not understand the principles of sustainability, and because the extension education system was…

  18. The ATLAS Forward Proton Detector (AFP)

    Science.gov (United States)

    Grinstein, S.; AFP Collaboration

    2016-04-01

    The ATLAS Forward Proton (AFP) detector will identify events in which one or two protons emerge intact from the proton-proton collisions at the LHC. Tracking and timing detectors will be placed 2-3 mm from the beam, 210 m away from the ATLAS interaction point. The silicon-based tracker will provide momentum measurement, while the time of flight system is used to reduce the background from multiple proton-proton collisions. The study of soft and hard diffractive events at low luminosities (μ ≈ 1) is the core of the AFP physics program. This paper presents an overview of the project with particular emphasis on the qualification of the pixel and timing systems.

  19. The clinical case for proton beam therapy

    Directory of Open Access Journals (Sweden)

    Foote Robert L

    2012-10-01

    Full Text Available Abstract Over the past 20 years, several proton beam treatment programs have been implemented throughout the United States. Increasingly, the number of new programs under development is growing. Proton beam therapy has the potential for improving tumor control and survival through dose escalation. It also has potential for reducing harm to normal organs through dose reduction. However, proton beam therapy is more costly than conventional x-ray therapy. This increased cost may be offset by improved function, improved quality of life, and reduced costs related to treating the late effects of therapy. Clinical research opportunities are abundant to determine which patients will gain the most benefit from proton beam therapy. We review the clinical case for proton beam therapy. Summary sentence Proton beam therapy is a technically advanced and promising form of radiation therapy.

  20. A Comparison Between Orion Automated and Space Shuttle Rendezvous Techniques

    Science.gov (United States)

    Ruiz, Jose O,; Hart, Jeremy

    2010-01-01

    The Orion spacecraft will replace the space shuttle and will be the first human spacecraft since the Apollo program to leave low earth orbit. This vehicle will serve as the cornerstone of a complete space transportation system with a myriad of mission requirements necessitating rendezvous to multiple vehicles in earth orbit, around the moon and eventually beyond . These goals will require a complex and robust vehicle that is, significantly different from both the space shuttle and the command module of the Apollo program. Historically, orbit operations have been accomplished with heavy reliance on ground support and manual crew reconfiguration and monitoring. One major difference with Orion is that automation will be incorporated as a key element of the man-vehicle system. The automated system will consist of software devoted to transitioning between events based on a master timeline. This effectively adds a layer of high level sequencing that moves control of the vehicle from one phase to the next. This type of automated control is not entirely new to spacecraft since the shuttle uses a version of this during ascent and entry operations. During shuttle orbit operations however many of the software modes and hardware switches must be manually configured through the use of printed procedures and instructions voiced from the ground. The goal of the automation scheme on Orion is to extend high level automation to all flight phases. The move towards automation represents a large shift from current space shuttle operations, and so these new systems will be adopted gradually via various safeguards. These include features such as authority-to-proceed, manual down modes, and functional inhibits. This paper describes the contrast between the manual and ground approach of the space shuttle and the proposed automation of the Orion vehicle. I will introduce typical orbit operations that are common to all rendezvous missions and go on to describe the current Orion automation

  1. Statistical analysis of SAMPEX PET proton measurements

    CERN Document Server

    Pierrard, V; Heynderickx, D; Kruglanski, M; Looper, M; Blake, B; Mewaldt, D

    2000-01-01

    We present a statistical study of the distributions of proton counts from the Proton-Electron Telescope aboard the low-altitude polar satellite SAMPEX. Our statistical analysis shows that histograms of observed proton counts are generally distributed according to Poisson distributions but are sometimes quite different. The observed departures from Poisson distributions can be attributed to variations of the average flux or to the non-constancy of the detector lifetimes.

  2. Sustainable Marketing : The Importance of Being a Sustainable Business

    OpenAIRE

    Reutlinger, Janina

    2012-01-01

    This thesis deals with sustainable marketing, as well as the necessity for more sustainability. The purpose of this thesis was to determine the importance of sustainable marketing for companies. The theoretical part is divided into sustainability and sustainable marketing. Sustainability covers current issues and sustainable development, which form a background for a better understanding of sustainable marketing. Sustainable marketing includes a definition of the concept, as well as susta...

  3. Very Forward proton-proton interactions with the LHCf detector

    CERN Document Server

    Tricomi, Alessia

    2013-01-01

    The LHCf experiment has been designed to precisely measure very forward neutral particle spectra produced in proton-proton collisions at LHC up to an energy of 14 TeV in the center of mass system. These measurements are of fundamental importance to calibrate the Monte Carlo models widely used in the high energy cosmic ray (HECR) field, up to an equivalent laboratory energy of the order of 1017 eV. In 2009-2010 the experiment has completed the p-p data taking at sqrt{s} = 0.9 TeV and sqrt{s}=7 TeV and the detectors have later on been removed from the tunnel region, when the LHC luminosity increased above 1030 cm-2s-1. In this paper the most up-to-date results on the inclusive photon spectra and the pi0 spectra measured by LHCf are reported. Comparison of these spectra with the model expectations and the impact on high energy cosmic ray (HECR) Physics are discussed. In addition, perspectives for future analyses as well as the program for the next data taking period, in particular the foreseen data taking in p-P...

  4. ππ Production in Proton-Proton Collisions

    Science.gov (United States)

    Skorodko, T.; Bashkanov, M.; Bogoslowsky, D.; Calén, H.; Cappellaro, F.; Clement, H.; Demiroers, L.; Ekström, C.; Fransson, K.; Greiff, J.; Gustafsson, L.; Höistad, B.; Ivanov, G.; Jacewicz, M.; Jiganov, E.; Johansson, T.; Kaskulov, M. M.; Keleta, S.; Khakimova, O.; Koch, I.; Kren, F.; Kullander, S.; Kupść, A.; Kuznetsov, A.; Marciniewski, P.; Meier, R.; Morosov, B.; Oelert, W.; Pauly, C.; Petukhov, Y.; Povtorejko, A.; Ruber, R. J. M. Y.; Schwick, A.; Scobel, W.; Shafigullin, R.; Shwartz, B.; Sopov, V.; Stepaniak, J.; Tchernyshev, V.; Thörngren-Engblom, P.; Tikhomirov, V.; Turowiecki, A.; Wagner, G. J.; Wolke, M.; Yamamoto, A.; Zabierowski, J.; Złomanćzuk, J.

    At CELSIUS-WASA the two-pion production in proton-proton collisisons has been measured exclusively from threshold up to the energy regime, where both of the collision partners are expected to be excited to the Δ state. The measurements constitute the first kinematically complete data samples of solid statistics in this energy range. Most of the data have been obtained for the π+π- and π0π0channels. Whereas at near-threshold energies the differential distributions can be succesfully explained by chiral dynamics and Roper excitation, respectively, the data for the π+π- channel in the ΔΔ region can be described only, if the special configuration (ΔΔ)0+ is assumed. The data for the π0π0 channel moreover exhibit a low-mass enhancement in the π0π0 invariant mass spectrum, which is reminiscent of the ABC-effect found in double-pionic fusion to light nuclei.

  5. Transverse relaxation of scalar-coupled protons.

    Science.gov (United States)

    Segawa, Takuya F; Baishya, Bikash; Bodenhausen, Geoffrey

    2010-10-25

    In a preliminary communication (B. Baishya, T. F. Segawa, G. Bodenhausen, J. Am. Chem. Soc. 2009, 131, 17538-17539), we recently demonstrated that it is possible to obtain clean echo decays of protons in biomolecules despite the presence of homonuclear scalar couplings. These unmodulated decays allow one to determine apparent transverse relaxation rates R(2) (app) of individual protons. Herein, we report the observation of R(2) (app) for three methyl protons, four amide H(N) protons, and all 11 backbone H(α) protons in cyclosporin A. If the proton resonances overlap, their R(2) (app) rates can be measured by transferring their magnetization to neighboring (13)C nuclei, which are less prone to overlap. The R(2) (app) rates of protons attached to (13)C are faster than those attached to (12)C because of (13)C-(1)H dipolar interactions. The differences of these rates allow the determination of local correlation functions. Backbone H(N) and H(α) protons that have fast decay rates R(2) (app) also feature fast longitudinal relaxation rates R(1) and intense NOESY cross peaks that are typical of crowded environments. Variations of R(2) (app) rates of backbone H(α) protons in similar amino acids reflect differences in local environments.

  6. Nuclear interaction cross sections for proton radiotherapy

    CERN Document Server

    Chadwick, M B; Arendse, G J; Cowley, A A; Richter, W A; Lawrie, J J; Newman, R T; Pilcher, J V; Smit, F D; Steyn, G F; Koen, J W; Stander, J A

    1999-01-01

    Model calculations of proton-induced nuclear reaction cross sections are described for biologically-important targets. Measurements made at the National Accelerator Centre are presented for double-differential proton, deuteron, triton, helium-3 and alpha particle spectra, for 150 and 200 MeV protons incident on C, N, and O. These data are needed for Monte Carlo simulations of radiation transport and absorbed dose in proton therapy. Data relevant to the use of positron emission tomography to locate the Bragg peak are also described.

  7. Saturating Cronin effect in ultrarelativistic proton-nucleus collisions

    OpenAIRE

    Papp, Gabor; Levai, Peter; Fai, George

    1999-01-01

    Pion and photon production cross sections are analyzed in proton-proton and proton-nucleus collisions at energies 20 GeV < s^1/2 < 60 GeV. We separate the proton-proton and nuclear contributions to transverse-momentum broadening and suggest a new mechanism for the nuclear enhancement in the high transverse-momentum region.

  8. Storage ring proton EDM experiment

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    sensitivity of 10^-29 e-cm.  The strength of the method originates from the fact that there are high intensity polarized proton beams available and the fact that the so-called geometric phase systematic error background cancels with clock-wise and counter-clock-wise storage possible in electric rings. The ultimate sensitivity of the method is 10^-30 e-cm. At this level it will either detect a non-zero EDM or it will eliminate electro-weak baryogenesis.

  9. SNS Proton Beam Window Disposal

    Science.gov (United States)

    Popova, Irina; Gallmeier, Franz X.; Trotter, Steven

    2017-09-01

    In order to support the disposal of the proton beam window assembly of the Spallation Neutron Source beamline to the target station, waste classification analyses are performed. The window has a limited life-time due to radiation-induced material damage. Analyses include calculation of the radionuclide inventory and shielding analyses for the transport package/container to ensure that the container is compliant with the transportation and waste management regulations. In order to automate this procedure and minimize manual work a script in Perl language was written.

  10. SNS Proton Beam Window Disposal

    Directory of Open Access Journals (Sweden)

    Popova Irina

    2017-01-01

    Full Text Available In order to support the disposal of the proton beam window assembly of the Spallation Neutron Source beamline to the target station, waste classification analyses are performed. The window has a limited life-time due to radiation-induced material damage. Analyses include calculation of the radionuclide inventory and shielding analyses for the transport package/container to ensure that the container is compliant with the transportation and waste management regulations. In order to automate this procedure and minimize manual work a script in Perl language was written.

  11. Proton beam therapy control system

    Science.gov (United States)

    Baumann, Michael A.; Beloussov, Alexandre V.; Bakir, Julide; Armon, Deganit; Olsen, Howard B.; Salem, Dana

    2010-09-21

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  12. Action Research for Sustainability

    DEFF Research Database (Denmark)

    Egmose, Jonas

    Analysing processes of social learning this work addresses how action research can further new research orientations towards sustainability. Empirically situated in the field of upstream public engagement, involving local residents, researchers and practitioners in bottom-up processes deliberating...... on urban sustainability the need to move towards sustainability at societal level is conceptualised as a democratic challenge questioning the way we live on planet earth. By understanding sustainability as an immanent and emergent ability of ecological and social life, continuously to renew itself without...... eroding its own foundation of existence, it argues that since sustainability cannot be invented but only supported (or eroded) by science, we need to reframe science in the role of sustaining sustain-ability. Through analyses of a three year action research programme, aiming to provide local citizens...

  13. Handbook of sustainable engineering

    CERN Document Server

    Lee, Kun-Mo

    2013-01-01

    "The efficient utilization of energy, sustainable use of natural resources, and large-scale adoption of sustainable technologies is the key to a sustainable future. The Handbook of Sustainable Engineering provides tools that will help us achieve these goals". Nobel Prize Winner Dr. R.K. Pauchauri, Chairman, UN Intergovernmental Panel on Climate Change As global society confronts the challenges of diminishing resources, ecological degradation, and climate change, engineers play a crucial role designing and building technologies and products that fulfil our needs for utility and sustainability. The Handbook of Sustainable Engineering equips readers with the context and the best practices derived from both academic research and practical examples of successful implementations of sustainable technical solutions. The handbook’s content revolves around the two themes, new ways of thinking and new business models, including sustainable production, products, service systems and consumption while addressing key asse...

  14. FORUM: Is Ecotourism Sustainable?

    Science.gov (United States)

    Wall

    1997-07-01

    / It is legitimate to ask whether and in what form tourism might contribute to sustainable development. This is not the same as sustainable tourism which, as a single-sector approach to development, may overlook important linkages with other sectors. If tourism is to contribute to sustainable development, then it must be economically viable, ecologically sensitive and culturally appropriate. Ecotourism is often advocated as being a sustainable form of tourism but imprecision in terminology clouds basic issues and there are strong economic, ecological, and cultural reasons for believing that, even in its purest forms, ecotourism is likely to present substantial challenges to destination areas, particularly if it competes for scarce resources and displaces existing uses and users. Sustainable tourism and ecotourism are not synonyms, many forms of ecotourism may not be sustainable, and if ecotourism is to contribute to sustainable development, then careful planning and management will be required.KEY WORDS: Ecotourism; Sustainable development; Development; Tourism

  15. Livestock biodiversity and sustainability

    NARCIS (Netherlands)

    Hoffmann, I.

    2011-01-01

    Sustainable development equally includes environmental protection including biodiversity, economic growth and social equity, both within and between generations. The paper first reviews different aspects related to the sustainable use of livestock biodiversity and property regimes that influence

  16. Sustainable Public Bids

    Directory of Open Access Journals (Sweden)

    Gil César Costa de Paula

    2016-06-01

    Full Text Available In this article we will discuss the issue of sustainability in public procurement, given that the government in Brazil is constituted as a great promoter of economic development and needs to adapt its acquisitions worldwide sustainability agenda.

  17. Theoretical study on conformation dynamics of three-station molecular shuttle in different environments and its influence on NMR chemical shifts and binding interactions.

    Science.gov (United States)

    Liu, Pingying; Li, Wei; Liu, Li; Wang, Leyong; Ma, Jing

    2014-10-02

    Microscopic information on conformational flexibility and macrocycle-thread binding interactions is helpful in rational design of novel multistation molecular shuttles with interesting topology and functions. Molecular dynamics (MD) was applied to simulate conformational changes of thread and macrocycle of a three-station molecular shuttle in different chemical environments (vacuum, CD3CN-CDCl3 solution, and crystal). In contrast with the highly distorted thread conformation in the gas phase and nonpolar CDCl3 solution, the solvated thread in CD3CN-CDCl3 (1:1) mix solvents exhibited a relatively rigid structure. Experimental observations of preferential binding at the protonated dibenzylammonium group (station I) were rationalized by quantum chemical calculations of macrocycle-thread binding energies at three different stations. The orthogonality of site-specific binding interactions at three different stations was also revealed by the nearly constant binding energy obtained at each specific recognition center with the replacement of different neighboring groups and terminal stoppers on the thread. Conformational flexibility has little effect on NMR signals of binding sites, but for some protons that are close to the solvent molecules in the first solvent shell, their chemical shifts are sensitive to the local electrostatic environment caused by nearby solvents. In crystal, π stacking induced evident upfield shifts of NMR signals in comparison with the isolated monomer.

  18. Influence of proton scattering angles on the energy radiograph in proton radiotherapy : A simulation study

    NARCIS (Netherlands)

    Biegun, A.K.; Takatsu, J.; van Beuzekom, M.; van der Graaf, E.R.; van Goethem, M-J.; Klaver, T.; Visser, J.; Brandenburg, S.

    2015-01-01

    The treatment quality of cancer patients with a proton beam critically depends on accurate predictions of proton stopping powers. Uncertainties in proton range that occur from translation of an X-ray CT patient image, of typical 3–4% or more, lead to necessary enlargements of contours around the

  19. Proton energy and scattering angle radiographs to improve proton treatment planning : a Monte Carlo study

    NARCIS (Netherlands)

    Biegun, Aleksandra; Takatsu, Jun; Nakaji, Taku; van Goethem, Marc-Jan; van der Graaf, Emiel; Koffeman, E.; Visser, Jan; Brandenburg, Sijtze

    2016-01-01

    The novel proton radiography imaging technique has a large potential to be used in direct measurement of the proton energy loss (proton stopping power, PSP) in various tissues in the patient. The uncertainty of PSPs, currently obtained from translation of X-ray Computed Tomography (xCT) images,

  20. Shuttle Diplomacy and Conflict Management: A Critical Analysis ...

    African Journals Online (AJOL)

    Given the often intractable nature of conflicts and the incidence of dysfunctional conflicts, warring parties continue with their destructive debate, repeating their non-negotiable positions and evil intent. This paper therefore argues for the need to revisit the existing mechanisms of shuttle diplomacy with a view to canvassing a ...

  1. Load control system. [for space shuttle external tank ground tests

    Science.gov (United States)

    Grosse, J. C.

    1977-01-01

    The load control system developed for the shuttle external structural tests is described. The system consists of a load programming/display module, and a load control module along with the following hydraulic system components: servo valves, dump valves, hydraulic system components, and servo valve manifold blocks. One load programming/display subsystem can support multiple load control subsystem modules.

  2. Applying reliability models to the maintenance of Space Shuttle software

    Science.gov (United States)

    Schneidewind, Norman F.

    1992-01-01

    Software reliability models provide the software manager with a powerful tool for predicting, controlling, and assessing the reliability of software during maintenance. We show how a reliability model can be effectively employed for reliability prediction and the development of maintenance strategies using the Space Shuttle Primary Avionics Software Subsystem as an example.

  3. Shuttle Program Information Management System (SPIMS) data base

    Science.gov (United States)

    1983-01-01

    The Shuttle Program Information Management System (SPIMS) is a computerized data base operations system. The central computer is the CDC 170-730 located at Johnson Space Center (JSC), Houston, Texas. There are several applications which have been developed and supported by SPIMS. A brief description is given.

  4. Accuracy analysis of the 2014–2015 Global Shuttle Radar ...

    Indian Academy of Sciences (India)

    Global Shuttle Radar Topography Mission (SRTM) data products have been widely used in EarthSciences without an estimation of their accuracy and reliability even though large outliers exist in them.The global 1 arc-sec, 30 m resolution, SRTM C-Band (C-30) data collected in February 2000 has beenrecently released ...

  5. The Flight of the Space Shuttle "Discovery" (STS-119)

    Science.gov (United States)

    Stinner, Arthur; Metz, Don

    2010-01-01

    This article is intended to model the ascent of the space shuttle for high school teachers and students. It provides a background for a sufficiently comprehensive description of the physics (kinematics and dynamics) of the March 16, 2009, "Discovery" launch. Our data are based on a comprehensive spreadsheet kindly sent to us by Bill Harwood, the…

  6. Design and Development of the Space Shuttle Tail Service Masts

    Science.gov (United States)

    Dandage, S. R.; Herman, N. A.; Godfrey, S. E.; Uda, R. T.

    1977-01-01

    The successful launch of a space shuttle vehicle depends on the proper operation of two tail service masts (TSMs). Reliable TSM operation is assured through a comprehensive design, development, and testing program. The results of the concept verification test (CVT) and the resulting impact on prototype TSM design are presented. The design criteria are outlined, and the proposed prototype TSM tests are described.

  7. Development of a waste collection system for the space shuttle.

    Science.gov (United States)

    Behrend, A. F., Jr.; Swider, J. E., Jr.

    1972-01-01

    The development of a waste collection system to accommodate both male and female crew members for the space shuttle is discussed. The waste collection system, with emphasis on the collection and transfer of urine, is described. Human-interface requirements, zero-gravity influences and effects, and operational considerations required for total system design are discussed.

  8. New timetable for the CERN Shuttle service 2015

    CERN Document Server

    2014-01-01

    Due to the reduction of operational budgets, please note that as from 5 January 2015: Circuit 1 (Meyrin) will not run during lunch; Circuit 2 (Prévessin) will run two more times each day; Circuit 6 will no longer run.   For more information: http://cern.ch/ShuttleService.   Departmental Administrative Office

  9. Indicators for environmental sustainability

    DEFF Research Database (Denmark)

    Dong, Yan; Hauschild, Michael Zwicky

    2017-01-01

    . In this study, we reviewed indicators applied in life cycle assessment (LCA), planetary boundary framework (PB), and Sustainable Development Goals (SDGs) developed under United Nation. The aim is to 1) identify their applications and relevant decision context; 2) Review their indicators and categorize them......Decision making on sustainable consumption and production requires scientifically based information on sustainability. Different environmental sustainability targets exist for specific decision problems. To observe how well these targets are met, relevant environmental indicators are needed...

  10. Aerospace News: Space Shuttle Commemoration. Volume 2, No. 7

    Science.gov (United States)

    2011-01-01

    The complex space shuttle design was comprised of four components: the external tank, two solid rocket boosters (SRB), and the orbiter vehicle. Six orbiters were used during the life of the program. In order of introduction into the fleet, they were: Enterprise (a test vehicle), Columbia, Challenger, Discovery, Atlantis and Endeavour. The space shuttle had the unique ability to launch into orbit, perform on-orbit tasks, return to earth and land on a runway. It was an orbiting laboratory, International Space Station crew delivery and supply replenisher, satellite launcher and payload delivery vehicle, all in one. Except for the external tank, all components of the space shuttle were designed to be reusable for many flights. ATK s reusable solid rocket motors (RSRM) were designed to be flown, recovered, and the metal components reused 20 times. Following each space shuttle launch, the SRBs would parachute into the ocean and be recovered by the Liberty Star and Freedom Star recovery ships. The recovered boosters would then be received at the Cape Canaveral Air Force Station Hangar AF facility for disassembly and engineering post-flight evaluation. At Hangar AF, the RSRM field joints were demated and the segments prepared to be returned to Utah by railcar. The segments were then shipped to ATK s facilities in Clearfield for additional evaluation prior to washout, disassembly and refurbishment. Later the refurbished metal components would be transported to ATK s Promontory facilities to begin a new cycle. ATK s RSRMs were manufactured in Promontory, Utah. During the Space Shuttle Program, ATK supported NASA s Marshall Space Flight Center whose responsibility was for all propulsion elements on the program, including the main engines and solid rocket motors. On launch day for the space shuttle, ATK s Launch Site Operations employees at Kennedy Space Center (KSC) provided lead engineering support for ground operations and NASA s chief engineer. It was ATK s responsibility

  11. Sustainable Learning Organizations

    Science.gov (United States)

    Velazquez, Luis E.; Esquer, Javier; Munguia, Nora E.; Moure-Eraso, Rafael

    2011-01-01

    Purpose: The purpose of this paper is to debate how companies may better become a sustainable learning organization by offering the most used and insightful concepts of sustainability. Design/methodology/approach: Through literature review, learning organization and sustainability perspectives are explored and compared. Findings: Learning…

  12. Measuring Educational Sustainability

    Science.gov (United States)

    Selvanathan, Rani G.

    2013-01-01

    There are many definitions that are attributable to the meaning of sustainability. Sustainability can be viewed as long-lasting, effective result of a project, venture, action, or investment without consuming additional future resources. Because of the wide nature of its applicability, a universal measure of sustainability is hard to come by. This…

  13. ORNL Annual Sustainability Report

    Energy Technology Data Exchange (ETDEWEB)

    Lapsa, Melissa Voss [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nichols, Teresa A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-02-01

    As described in this report, we have made substantial progress across the 25 roadmaps of the Sustainable Campus Initiative. The report also outlines our plans to continue integrating sustainable practices into the planning, execution, and evaluation of all ORNL activities. We appreciate your interest in our journey to sustainability, and we welcome your comments, questions, and suggestions.

  14. Toward sustainable logistics

    NARCIS (Netherlands)

    Soysal, Mehmet; Bloemhof-Ruwaard, Jacqueline M.

    2017-01-01

    The fast evolution of sustainability leads to the development of a new fast-growing concept called sustainable logistics management. This research addresses recent business trends and challenges in logistics and their implications for sustainable logistics management. Additionally, we discuss policy

  15. LCA and Sustainability

    DEFF Research Database (Denmark)

    Moltesen, Andreas; Bjørn, Anders

    2017-01-01

    LCA is often presented as a sustainability assessment tool. This chapter analyses the relationship between LCA and sustainability. This is done by first outlining the history of the sustainability concept, which gained momentum with the Brundtland Commission’s report ‘Our Common Future report ’ i...

  16. Lean maturity, lean sustainability

    DEFF Research Database (Denmark)

    Jørgensen, Frances; Matthiesen, Rikke; Nielsen, Jacob

    2007-01-01

    Although lean is rapidly growing in popularity, its implementation is far from problem free and companies may experience difficulties sustaining long term success. In this paper, it is suggested that sustainable lean requires attention to both performance improvement and capability development...... that support lean capability development and consequently, lean sustainability....

  17. Food sustainability: diverging interpretations

    NARCIS (Netherlands)

    Aiking, H.; de Boer, J.

    2004-01-01

    The concept of sustainability in general and food sustainability, in particular, entails many aspects and many interpretations. During a conference on food sustainability a broad, multidisciplinary picture was painted and many key issues were dealt with, from ecology, economy and society. In

  18. Transferring Education for Sustainability

    Science.gov (United States)

    Gafoor, Kunnathodi Abdul; Umer Farooque, T. K.

    2013-01-01

    Sustainability stands for sustaining the past, meeting needs of the present without compromising the ability to meet future needs. It should meet the individual and social needs, present and future needs local and global needs. A sustainable education that meets this requirements surely be a transferable education; an education that transfers from…

  19. Sustainability: An Overview.

    Science.gov (United States)

    Wormsley, W. E.

    1990-01-01

    This article introduces a group of six papers on sustainability of programs for visually handicapped persons in developing countries. Sustainability is discussed from an anthropological perspective, noting the importance of a social soundness analysis and a social impact assessment, enemies of sustainability, and the need for broad local input in…

  20. Sustainability in logistics practice

    NARCIS (Netherlands)

    Hans-Heinrich Glöckner; Reinder Pieters; Stef Weijers

    2009-01-01

    This conceptual paper wants to emphasis the use of the concept of sustainability within logistics and especially transportation. While working on a new tool to help companies develop sustainable European networks, we discovered that we want to use a specific concept of sustainability: People, planet

  1. Charged-Particle Multiplicity Distributions over Wide Pseudorapidity Range in Proton-Proton and Proton-Lead Collisions with ALICE

    DEFF Research Database (Denmark)

    Zaccolo, Valentina

    The charged–particle distribution (P(Nch) as a function of Nch), producedin high energy collisions between protons (pp) and between protons and heavynucleus (pPb), depends on the fundamental processes, which lead to the formationof the observed particles. In particular, the so–called multiplicity...

  2. Measurement of pion, kaon and proton production in proton-proton collisions at root s=7 TeV

    NARCIS (Netherlands)

    Adam, J.; Adamova, D.; Aggarwal, M. M.; Rinella, G. Aglieri; Agnello, M.; Agrawal, N.; Ahammed, Z.; Ahmed, I.; Ahn, S. U.; Aimo, I.; Aiola, S.; Ajaz, M.; Akindinov, A.; Alam, S. N.; Aleksandrov, D.; Alessandro, B.; Alexandre, D.; Molina, R. Alfaro; Alici, A.; Alkin, A.; Alme, J.; Alt, T.; Altinpinar, S.; Altsybeev, I.; Prado, C. Alves Garcia; Andrei, C.; Andronic, A.; Anguelov, V.; Anielski, J.; Anticic, T.; Antinori, F.; Antonioli, P.; Aphecetche, L.; Appelshaeuser, H.; Arcelli, S.; Armesto, N.; Arnaldi, R.; Aronsson, T.; Arsene, I. C.; Arslandok, M.; Augustinus, A.; Averbeck, R.; Azmi, M. D.; Bach, M.; Badala, A.; Baek, Y. W.; Bagnasco, S.; Bailhache, R.; Bala, R.; Baldisseri, A.; Ball, M.; Pedrosa, F. Baltasar Dos Santos; Baral, R. C.; Barbano, A. M.; Barbera, R.; Barile, F.; Barnafoeldi, G. G.; Barnby, L. S.; Barret, V.; Bartalini, P.; Bartke, J.; Bartsch, E.; Basile, M.; Bastid, N.; Basu, S.; Bathen, B.; Batigne, G.; Camejo, A. Batista; Batyunya, B.; Batzing, P. C.; Bearden, I. G.; Beck, H.; Bedda, C.; Behera, N. K.; Belikov, I.; Bellini, F.; Martinez, H. Bello; Bellwied, R.; Belmont, R.; Belmont-Moreno, E.; Belyaev, V.; Bencedi, G.; Beole, S.; Berceanu, I.; Bercuci, A.; Berdnikov, Y.; Berenyi, D.; Bertens, R. A.; Berzano, D.; Betev, L.; Bhasin, A.; Bhat, I. R.; Bhati, A. K.; Bhattacharjee, B.; Bhom, J.; Bianchi, L.; Bianchi, N.; Bianchin, C.; Bielcik, J.; Bielcikova, J.; Bilandzic, A.; Biswas, S.; Bjelogrlic, S.; Blanco, F.; Blau, D.; Blume, C.; Bock, F.; Bogdanov, A.; Boggild, H.; Boldizsar, L.; Bombara, M.; Book, J.; Borel, H.; Borissov, A.; Borri, M.; Bossu, F.; Botje, M.; Botta, E.; Boettger, S.; Braun-Munzinger, P.; Bregant, M.; Breitner, T.; Broker, T. A.; Browning, T. A.; Broz, M.; Brucken, E. J.; Bruna, E.; Bruno, G. E.; Budnikov, D.; Buesching, H.; Bufalino, S.; Buncic, P.; Busch, O.; Buthelezi, Z.; Buxton, J. T.; Caffarri, D.; Cai, X.; Caines, H.; Diaz, L. Calero; Caliva, A.; Villar, E. Calvo; Camerini, P.; Carena, F.; Carena, W.; Castellanos, J. Castillo; Castro, A. J.; Casula, E. A. R.; Cavicchioli, C.; Sanchez, C. Ceballos; Cepila, J.; Cerello, P.; Chang, B.; Chapeland, S.; Chartier, M.; Charvet, J. L.; Chattopadhyay, S.; Chattopadhyay, S.; Chelnokov, V.; Cherney, M.; Cheshkov, C.; Cheynis, B.; Barroso, V. Chibante; Chinellato, D. D.; Chochula, P.; Choi, K.; Chojnacki, M.; Choudhury, S.; Christakoglou, P.; Christensen, C. H.; Christiansen, P.; Chujo, T.; Chung, S. U.; Cicalo, C.; Cifarelli, L.; Cindolo, F.; Cleymans, J.; Colamaria, F.; Colella, D.; Collu, A.; Colocci, M.; Balbastre, G. Conesa; del Valle, Z. Conesa; Connors, M. E.; Contreras, J. G.; Cormier, T. M.; Morales, Y. Corrales; Maldonado, I. Cortes; Cortese, P.; Cosentino, M. R.; Costa, F.; Crochet, P.; Albino, R. Cruz; Cuautle, E.; Cunqueiro, L.; Dahms, T.; Dainese, A.; Danu, A.; Das, D.; Das, I.; Das, S.; Dash, A.; Dash, S.; De, S.; De Caro, A.; de Cataldo, G.; de Cuveland, J.; De Falco, A.; De Gruttola, D.; De Marco, N.; De Pasquale, S.; Deisting, A.; Deloff, A.; Denes, E.; D'Erasmo, G.; Di Bari, D.; Di Mauro, A.; Di Nezza, P.; Diaz Corchero, M. A.; Dietel, T.; Dillenseger, P.; Divia, R.; Djuvsland, O.; Dobrin, A.; Dobrowolski, T.; Domenicis Gimenez, D.; Dnigus, B.; Dordic, O.; Dubey, A. K.; Dubla, A.; Ducroux, L.; Dupieux, P.; Ehlers, R. J.; Elia, D.; Engel, H.; Erazmus, B.; Erhardt, F.; Eschweiler, D.; Espagnon, B.; Estienne, M.; Esumi, S.; Eum, J.; Evans, D.; Evdokimov, S.; Eyyubova, G.; Fabbietti, L.; Fabris, D.; Faivre, J.; Fantoni, A.; Fasel, M.; Feldkamp, L.; Felea, D.; Feliciello, A.; Feofilov, G.; Ferencei, J.; Fernandez Tellez, A.; Ferreiro, E. G.; Ferretti, A.; Festanti, A.; Figiel, J.; Figueredo, M. A. S.; Filchagin, S.; Finogeev, D.; Fionda, F. M.; Fiore, E. M.; Fleck, M. G.; Floris, M.; Foertsch, S.; Foka, P.; Fokin, S.; Fragiacomo, E.; Francescon, A.; Frankenfeld, U.; Fuchs, U.; Furget, C.; Furs, A.; Girard, M. Fusco; Gaardhoje, J. J.; Gagliardi, M.; Gago, A. M.; Gallio, M.; Gangadharan, D. R.; Ganoti, P.; Gao, C.; Garabatos, C.; Garcia-Solis, E.; Gargiulo, C.; Gasik, P.; Germain, M.; Gheata, A.; Gheata, M.; Ghosh, P.; Ghosh, S. K.; Gianotti, P.; Giubellino, P.; Giubilato, P.; Dziadus, E. Gladysz; Glaessel, P.; Ramirez, A. Gomez; Gonzalez Zamora, P.; Gorbunov, S.; Goerlich, L.; Gotovac, S.; Grabski, V.; Graczykowski, L. K.; Grelli, A.; Grigoras, A.; Grigoras, C.; Grigoriev, V.; Grigoryan, A.; Grigoryan, S.; Grinyov, B.; Grion, N.; Grosse-Oetringhaus, J. F.; Grossiord, J. -Y.; Grosso, R.; Guber, F.; Guernane, R.; Guerzoni, B.; Gulbrandsen, K.; Gulkanyan, H.; Gunji, T.; Gupta, A.; Gupta, R.; Haake, R.; Haaland, O.; Hadjidakis, C.; Haiduc, M.; Hamagaki, H.; Hamar, G.; Hanratty, L. D.; Hansen, A.; Harris, J. W.; Hartmann, H.; Harton, A.; Hatzifotiadou, D.; Hayashi, S.; Heckel, S. T.; Heide, M.; Helstrup, H.; Herghelegiu, A.; Herrera Corral, G.; Hess, B. A.; Hetland, K. F.; Hilden, T. E.; Hillemanns, H.; Hippolyte, B.; Hristov, P.; Huang, M.; Humanic, T. J.; Hussain, N.; Hussain, T.; Hutter, D.; Hwang, D. S.; Ilkaev, R.; Ilkiv, I.; Inaba, M.; Ionita, C.; Ippolitov, M.; Irfan, M.; Ivanov, M.; Ivanov, V.; Izucheev, V.; Jacobs, P. M.; Jahnke, C.; Jang, H. J.; Janik, M. A.; Jayarathna, P. H. S. Y.; Jena, C.; Jena, S.; Jimenez Bustamante, R. T.; Jones, P. G.; Jung, H.; Jusko, A.; Kalinak, P.; Kalweit, A.; Kamin, J.; Kang, J. H.; Kaplin, V.; Kar, S.; Uysal, A. Karasu; Karavichev, O.; Karavicheva, T.; Karpechev, E.; Kebschull, U.; Keidel, R.; Keijdener, D. L. D.; Keil, M.; Khan, K. H.; Khan, M. M.; Khan, P.; Khan, S. A.; Khanzadeev, A.; Kharlov, Y.; Kileng, B.; Kim, B.; Kim, D. W.; Kim, D. J.; Kim, H.; Kim, J. S.; Kim, M.; Kim, M.; Kim, S.; Kim, T.; Kirsch, S.; Kisel, I.; Kiselev, S.; Kisiel, A.; Kiss, G.; Klay, J. L.; Klein, C.; Klein, J.; Klein-Boesing, C.; Kluge, A.; Knichel, M. L.; Knospe, A. G.; Kobayashi, T.; Kobdaj, C.; Kofarago, M.; Koehler, M. K.; Kollegger, T.; Kolojvari, A.; Kondratiev, V.; Kondratyeva, N.; Kondratyuk, E.; Konevskikh, A.; Kouzinopoulos, C.; Kovalenko, O.; Kovalenko, V.; Kowalski, M.; Kox, S.; Meethaleveedu, G. Koyithatta; Kral, J.; Kralik, I.; Kravcakova, A.; Krelina, M.; Kretz, M.; Krivda, M.; Krizek, F.; Kryshen, E.; Krzewicki, M.; Kubera, A. M.; Kucera, V.; Kucheriaev, Y.; Kugathasan, T.; Kuhn, C.; Kuijer, P. G.; Kulakov, I.; Kumar, J.; Kumar, L.; Kurashvili, P.; Kurepin, A.; Kurepin, A. B.; Kuryakin, A.; Kushpil, S.; Kweon, M. J.; Kwon, Y.; La Pointe, S. L.; La Rocca, P.; Lagana Fernandes, C.; Lakomov, I.; Langoy, R.; Lara, C.; Lardeux, A.; Lattuca, A.; Laudi, E.; Lea, R.; Leardini, L.; Lee, G. R.; Lee, S.; Legrand, I.; Lehnert, J.; Lemmon, R. C.; Lenti, V.; Leogrande, E.; Monzon, I. Leon; Leoncino, M.; Levai, P.; Li, S.; Li, X.; Lien, J.; Lietava, R.; Lindal, S.; Lindenstruth, V.; Lippmann, C.; Lisa, M. A.; Ljunggren, H. M.; Lodato, D. F.; Loenne, P. I.; Loggins, V. R.; Loginov, V.; Loizides, C.; Lopez, X.; Lopez Torres, E.; Lowe, A.; Lu, X. -G.; Luettig, P.; Lunardon, M.; Luparello, G.; Maevskaya, A.; Mager, M.; Mahajan, S.; Mahmood, S. M.; Maire, A.; Majka, R. D.; Malaev, M.; Maldonado Cervantes, I.; Malinina, L.; Mal'Kevich, D.; Malzacher, P.; Mamonov, A.; Manceau, L.; Manko, V.; Manso, F.; Manzari, V.; Marchisone, M.; Mares, J.; Margagliotti, G. V.; Margotti, A.; Margutti, J.; Marin, A.; Markert, C.; Marquard, M.; Martin, N. A.; Blanco, J. Martin; Martinengo, P.; Martinez, M. I.; Garcia, G. Martinez; Pedreira, M. Martinez; Martynov, Y.; Mas, A.; Masciocchi, S.; Masera, M.; Masoni, A.; Massacrier, L.; Mastroserio, A.; Masui, H.; Matyja, A.; Mayer, C.; Mazer, J.; Mazzoni, M. A.; Mcdonald, D.; Meddi, F.; Menchaca-Rocha, A.; Meninno, E.; Perez, J. Mercado; Meres, M.; Miake, Y.; Mieskolainen, M. M.; Mikhaylov, K.; Milano, L.; Milosevic, J.; Minervini, L. M.; Mischke, A.; Mishra, A. N.; Miskowiec, D.; Mitra, J.; Mitu, C. M.; Mohammadi, N.; Mohanty, B.; Molnar, L.; Montano Zetina, L.; Montes, E.; Morando, M.; De Godoy, D. A. Moreira; Moretto, S.; Morreale, A.; Morsch, A.; Muccifora, V.; Mudnic, E.; Muehlheim, D.; Muhuri, S.; Mukherjee, M.; Mueller, H.; Mulligan, J. D.; Munhoz, M. G.; Murray, S.; Musa, L.; Musinsky, J.; Nandi, B. K.; Nania, R.; Nappi, E.; Naru, M. U.; Nattrass, C.; Nayak, K.; Nayak, T. K.; Nazarenko, S.; Nedosekin, A.; Nellen, L.; Ng, F.; Nicassio, M.; Niculescu, M.; Niedziela, J.; Nielsen, B. S.; Nikolaev, S.; Nikulin, S.; Nikulin, V.; Noferini, F.; Nomokonov, P.; Nooren, G.; Norman, J.; Nyanin, A.; Nystrand, J.; Oeschler, H.; Oh, S.; Oh, S. K.; Ohlson, A.; Okatan, A.; Okubo, T.; Olah, L.; Oleniacz, J.; Oliveira Da Silva, A. C.; Oliver, M. H.; Onderwaater, J.; Oppedisano, C.; Ortiz Velasquez, A.; Oskarsson, A.; Otwinowski, J.; Oyama, K.; Ozdemir, M.; Pachmayer, Y.; Pagano, P.; Paic, G.; Pajares, C.; Pal, S. K.; Pan, J.; Pandey, A. K.; Pant, D.; Papikyan, V.; Pappalardo, G. S.; Pareek, P.; Park, W. J.; Parmar, S.; Passfeld, A.; Paticchio, V.; Paul, B.; Pawlak, T.; Peitzmann, T.; Da Costa, H. Pereira; Pereira De Oliveira Filho, E.; Peresunko, D.; Lara, C. E. Perez; Peskov, V.; Pestov, Y.; Petracek, V.; Petrov, V.; Petrovici, M.; Petta, C.; Piano, S.; Pikna, M.; Pillot, P.; Pinazza, O.; Pinsky, L.; Piyarathna, D. B.; Ploskon, M.; Planinic, M.; Pluta, J.; Pochybova, S.; Podesta-Lerma, P. L. M.; Poghosyan, M. G.; Polichtchouk, B.; Poljak, N.; Poonsawat, W.; Pop, A.; Porteboeuf-Houssais, S.; Porter, J.; Pospisil, J.; Prasad, S. K.; Preghenella, R.; Prino, F.; Pruneau, C. A.; Pshenichnov, I.; Puccio, M.; Puddu, G.; Pujahari, P.; Punin, V.; Putschke, J.; Qvigstad, H.; Rachevski, A.; Raha, S.; Rajput, S.; Rak, J.; Rakotozafindrabe, A.; Ramello, L.; Raniwala, R.; Raniwala, S.; Rasanen, S. S.; Rascanu, B. T.; Rathee, D.; Razazi, V.; Read, K. F.; Real, J. S.; Redlich, K.; Reed, R. J.; Rehman, A.; Reichelt, P.; Reicher, M.; Reidt, F.; Ren, X.; Renfordt, R.; Reolon, A. R.; Reshetin, A.; Rettig, F.; Revol, J. -P.; Reygers, K.; Riabov, V.; Ricci, R. A.; Richert, T.; Richter, M.; Riedler, P.; Riegler, W.; Riggi, F.; Ristea, C.; Rivetti, A.; Rocco, E.; Rodriguez Cahuantzi, M.; Manso, A. Rodriguez; Roed, K.; Rogochaya, E.; Rohr, D.; Roehrich, D.; Romita, R.; Ronchetti, F.; Ronflette, L.; Rosnet, P.; Rossi, A.; Roukoutakis, F.; Roy, A.; Roy, C.; Roy, P.; Rubio Montero, A. J.; Rui, R.; Russo, R.; Ryabinkin, E.; Ryabov, Y.; Rybicki, A.; Sadovsky, S.; Safarik, K.; Sahlmuller, B.; Sahoo, P.; Sahoo, R.; Sahoo, S.; Sahu, P. K.; Saini, J.; Sakai, S.; Saleh, M. A.; Salgado, C. A.; Salzwedel, J.; Sambyal, S.; Samsonov, V.; Castro, X. Sanchez; Sandor, L.; Sandoval, A.; Sano, M.; Santagati, G.; Sarkar, D.; Scapparone, E.; Scarlassara, F.; Scharenberg, R. P.; Schiaua, C.; Schicker, R.; Schmidt, C.; Schmidt, H. R.; Schuchmann, S.; Schukraft, J.; Schulc, M.; Schuster, T.; Schutz, Y.; Schwarz, K.; Schweda, K.; Scioli, G.; Scomparin, E.; Scott, R.; Seeder, K. S.; Seger, J. E.; Sekiguchi, Y.; Selyuzhenkov, I.; Senosi, K.; Seo, J.; Serradilla, E.; Sevcenco, A.; Shabanov, A.; Shabetai, A.; Shadura, O.; Shahoyan, R.; Shangaraev, A.; Sharma, A.; Sharma, N.; Shigaki, K.; Shtejer, K.; Sibiriak, Y.; Siddhanta, S.; Sielewicz, K. M.; Siemiarczuk, T.; Silvermyr, D.; Silvestre, C.; Simatovic, G.; Simonetti, G.; Singaraju, R.; Singh, R.; Singha, S.; Singhal, V.; Sinha, B. C.; Sinha, T.; Sitar, B.; Sitta, M.; Skaali, T. B.; Slupecki, M.; Smirnov, N.; Snellings, R. J. M.; Snellman, T. W.; Sogaard, C.; Soltz, R.; Song, J.; Song, M.; Song, Z.; Soramel, F.; Sorensen, S.; Spacek, M.; Spiriti, E.; Sputowska, I.; Stassinaki, M. Spyropoulou; Srivastava, B. K.; Stachel, J.; Stan, I.; Stefanek, G.; Steinpreis, M.; Stenlund, E.; Steyn, G.; Stiller, J. H.; Stocco, D.; Strmen, P.; Suaide, A. A. P.; Sugitate, T.; Suire, C.; Suleymanov, M.; Sultanov, R.; Sumbera, M.; Symons, T. J. M.; Szabo, A.; De Toledo, A. Szanto; Szarka, I.; Szczepankiewicz, A.; Szymanski, M.; Takahashi, J.; Tanaka, N.; Tangaro, M. A.; Takaki, J. D. Tapia; Peloni, A. Tarantola; Tariq, M.; Tarzila, M. G.; Tauro, A.; Munoz, G. Tejeda; Telesca, A.; Terasaki, K.; Terrevoli, C.; Teyssier, B.; Thaeder, J.; Thomas, D.; Tieulent, R.; Timmins, A. R.; Toia, A.; Trogolo, S.; Trubnikov, V.; Trzaska, W. H.; Tsuji, T.; Tumkin, A.; Turrisi, R.; Tveter, T. S.; Ullaland, K.; Uras, A.; Usai, G. L.; Utrobicic, A.; Vajzer, M.; Vala, M.; Palomo, L. Valencia; Vallero, S.; Van der Maarel, J.; Van Hoorne, J. W.; Van Leeuwen, M.; Vanat, T.; Vyvre, P. Vande; Varga, D.; Vargas, A.; Vargyas, M.; Varma, R.; Vasileiou, M.; Vasiliev, A.; Vauthier, A.; Vechernin, V.; Veen, A. M.; Veldhoen, M.; Velure, A.; Venaruzzo, M.; Vercellin, E.; Limon, S. Vergara; Vernet, R.; Verweij, M.; Vickovic, L.; Viesti, G.; Viinikainen, J.; Vilakazi, Z.; Baillie, O. Villalobos; Vinogradov, A.; Vinogradov, L.; Vinogradov, Y.; Virgili, T.; Vislavicius, V.; Viyogi, Y. P.; Vodopyanov, A.; Vlkl, M. A.; Voloshin, K.; Voloshin, S. A.; Volpe, G.; Von Haller, B.; Vorobyev, I.; Vranic, D.; Vrlakova, J.; Vulpescu, B.; Vyushin, A.; Wagner, B.; Wagner, J.; Wang, H.; Wang, M.; Wang, Y.; Watanabe, D.; Weber, M.; Weber, S. G.; Wessels, J. P.; Westerhoff, U.; Wiechula, J.; Wikne, J.; Wilde, M.; Wilk, G.; Wilkinson, J.; Williams, M. C. S.; Windelband, B.; Winn, M.; Yaldo, C. G.; Yamaguchi, Y.; Yang, H.; Yang, P.; Yano, S.; Yasnopolskiy, S.; Yin, Z.; Yokoyama, H.; Yoo, I. -K.; Yurchenko, V.; Yushmanov, I.; Zaborowska, A.; Zaccolo, V.; Zaman, A.; Zampolli, C.; Zanoli, H. J. C.; Zaporozhets, S.; Zarochentsev, A.; Zavada, P.; Zaviyalov, N.; Zbroszczyk, H.; Zgura, I. S.; Zhalov, M.; Zhang, H.; Zhang, X.; Zhang, Y.; Zhao, C.; Zhigareva, N.; Zhou, D.; Zhou, Y.; Zhou, Z.; Zhu, H.; Zhu, J.; Zhu, X.; Zichichi, A.; Zimmermann, A.; Zimmermann, M. B.; Zinovjev, G.; Zyzak, M.

    2015-01-01

    The measurement of primary pi(+/-), K-+/-, p and (p) over bar production at mid-rapidity (|y| <0.5) in proton-proton collisions at root s = 7 TeV performed with a large ion collider experiment at the large hadron collider (LHC) is reported. Particle identification is performed using the specific

  3. Proton pump inhibitors and osteoporosis

    DEFF Research Database (Denmark)

    Andersen, Bjarne Nesgaard; Johansen, Per Birger; Abrahamsen, Bo

    2016-01-01

    PURPOSE OF REVIEW: The purpose of the review is to provide an update on recent advances in the evidence based on proton pump inhibitors (PPI) as a possible cause of osteoporosis and osteoporotic fractures. This review focuses, in particular, on new studies published in the last 18 months and a di......PURPOSE OF REVIEW: The purpose of the review is to provide an update on recent advances in the evidence based on proton pump inhibitors (PPI) as a possible cause of osteoporosis and osteoporotic fractures. This review focuses, in particular, on new studies published in the last 18 months...... and a discussion of these findings and how this has influenced our understanding of this association, the clinical impact and the underlying pathophysiology. RECENT FINDINGS: New studies have further strengthened existing evidence linking use of PPIs to osteoporosis. Short-term use does not appear to pose a lower...... risk than long-term use. There is a continued lack of conclusive studies identifying the pathogenesis. Direct effects on calcium absorption or on osteoblast or osteoclast action cannot at present plausibly explain the mechanism. SUMMARY: The use of PPIs is a risk factor for development of osteoporosis...

  4. The ATLAS Forward Proton Programme

    CERN Document Server

    Trzebinski, M; The ATLAS collaboration

    2012-01-01

    The ATLAS Forward Proton Programme - talk for the Low-x 2012 Meeting Quartic anomalous couplings measurement at μ = 46 and a total luminosity of 300 fb−1 is possible. The full AFP simulation in presence of pile-up confirms the gain in sensitivity between one and two orders of magnitude with respect to the standard (non-AFP) ATLAS methods. The use of the AFP allows reaching the values expected in Higgs-less or extra-dimension models. The production of exclusive dijet for μ = 23 and a total luminosity of 40 fb−1 the measurement is possible and interesting due to the huge model uncertainties at present level of the theory understanding. The measurement of the W asymmetry in a specific configuration at low μ allows to get a decisive understanding on the diffractive exchange. For all physics cases, AFP capabilities in terms of proton tagging and timing resolution are key and unique features unprecedented sensitivity to quartic anomalous coupling or novel QCD measurements.

  5. Legacy of Environmental Research During the Space Shuttle Program

    Science.gov (United States)

    Lane, Helen W.

    2011-01-01

    The Space Shuttle Program provided many opportunities to study the role of spaceflight on human life for over the last 30 years and represents the longest and largest U.S. human spaceflight program. Risks to crewmembers were included in the research areas of nutrition, microbiology, toxicology, radiation, and sleep quality. To better understand the Shuttle environment, Crew Health Care System was developed. As part of this system, the Environmental Health Subsystem was developed to monitor the atmosphere for gaseous contaminants and microbial contamination levels and to monitor water quality and radiation. This program expended a great deal of effort in studying and mitigating risks related to contaminations due to food, water, air, surfaces, crewmembers, and payloads including those with animals. As the Shuttle had limited stowage space and food selection, the development of nutritional requirements for crewmembers was imperative. As the Shuttle was a reusable vehicle, microbial contamination was of great concern. The development of monitoring instruments that could withstand the space environment took several years and many variations to come up with a suitable instrument. Research with space radiation provided an improved understanding of the various sources of ionizing radiation and the development of monitoring instrumentation for space weather and the human exposure within the orbiter's cabin. Space toxicology matured to include the management of offgassing products that could pollute the crewmembers air quality. The Shuttle Program implemented a 5-level toxicity rating system and developed new monitoring instrumentation to detect toxic compounds. The environment of space caused circadian desynchrony, sleep deficiency, and fatigue leading to much research and major emphasis on countermeasures. Outcomes of the research in these areas were countermeasures, operational protocols, and hardware. Learning Objectives: This symposium will provide an overview of the

  6. Shuttle measured contaminant environment and modeling for payloads. Preliminary assessment of the space telescope environment in the shuttle bay

    Science.gov (United States)

    Scialdone, J. J.

    1983-01-01

    A baseline gaseous and particulate environment of the Shuttle bay was developed based on the various measurements which were made during the first four flights of the Shuttle. The environment is described by the time dependent pressure, density, scattered molecular fluxes, the column densities and including the transient effects of water dumps, engine firings and opening and closing of the bay doors. The particulate conditions in the ambient and on surfaces were predicted as a function of the mission time based on the available data. This basic Shuttle environment when combined with the outgassing and the particulate contributions of the payloads, can provide a description of the environment of a payload in the Shuttle bay. As an example of this application, the environment of the Space Telescope in the bay, which may be representative of the environment of several payloads, was derived. Among the many findings obtained in the process of modeling the environment, one is that the payloads environment in the bay is not substantially different or more objectionable than the self-generated environment of a large payload or spacecraft. It is, however, more severe during ground facilities operations, the first 15 to 20 hours of the flight, during and for a short period after ater was dumped overboard, and the reaction control engines are being fired.

  7. LCA and Sustainability

    DEFF Research Database (Denmark)

    Moltesen, Andreas; Bjørn, Anders

    2017-01-01

    LCA is often presented as a sustainability assessment tool. This chapter analyses the relationship between LCA and sustainability. This is done by first outlining the history of the sustainability concept, which gained momentum with the Brundtland Commission’s report ‘Our Common Future report...... is then demonstrated, and the strategy of LCA to achieving environmental protection, namely to guide the reduction of environmental impacts per delivery of a function, is explained. The attempt to broaden the scope of LCA, beyond environmental protection, by so-called life cycle sustainability assessment (LCSA......) is outlined. Finally, the limitations of LCA in guiding a sustainable development are discussed....

  8. Centroid theory of transverse electron-proton two-stream instability in a long proton bunch

    Directory of Open Access Journals (Sweden)

    Tai-Sen F. Wang

    2003-01-01

    Full Text Available This paper presents an analytical investigation of the transverse electron-proton (e-p two-stream instability in a proton bunch propagating through a stationary electron background. The equations of motion, including damping effects, are derived for the centroids of the proton beam and the electron cloud by considering Lorentzian and Gaussian frequency spreads for the particles. For a Lorentzian frequency distribution, we derive the asymptotic solution of the coupled linear centroid equations in the time domain and study the e-p instability in proton bunches with nonuniform line densities. Examples are given for both uniform and parabolic proton line densities.

  9. Wings In Orbit: Scientific and Engineering Legacies of the Space Shuttle

    Science.gov (United States)

    Hale, N. Wayne (Editor); Lulla, Kamlesh (Editor); Lane, Helen W. (Editor); Chapline, Gail (Editor)

    2010-01-01

    This Space Shuttle book project reviews Wings In Orbit-scientific and engineering legacies of the Space Shuttle. The contents include: 1) Magnificent Flying Machine-A Cathedral to Technology; 2) The Historical Legacy; 3) The Shuttle and its Operations; 4) Engineering Innovations; 5) Major Scientific Discoveries; 6) Social, Cultural, and Educational Legacies; 7) Commercial Aerospace Industries and Spin-offs; and 8) The Shuttle continuum, Role of Human Spaceflight.

  10. Sensitivity of Space Shuttle Weight and Cost to Structure Subsystem Weights

    Science.gov (United States)

    Wedge, T. E.; Williamson, R. P.

    1973-01-01

    Quantitative relationships between changes in space shuttle weights and costs with changes in weight of various portions of space shuttle structural subsystems are investigated. These sensitivity relationships, as they apply at each of three points in the development program (preliminary design phase, detail design phase, and test/operational phase) have been established for five typical space shuttle designs, each of which was responsive to the missions in the NASA Shuttle RFP, and one design was that selected by NASA.

  11. From sustainable buildings to sustainable business

    OpenAIRE

    Mia Andelin

    2012-01-01

    The United Nations Environment Program (UNEP) Sustainable Buildings & Climate Initiative reports that buildings are responsible for more than 40 percent of global energy use and over one third of global greenhouse gas (GHG) emissions. The construction and real estate sector has the potential to play a significant role in the response to climate change. During the latest years the increase in attention to sustainability and green building by planners, developers, and investors has been remarka...

  12. The quark fraction of the proton spin

    Energy Technology Data Exchange (ETDEWEB)

    Mandula, J.E. (Department of Energy, Washington, DC (United States). Div. of High Energy Physics)

    1992-05-01

    We report on a lattice QCD estimate of the fraction of the proton spin that the quark spin is responsible for. The estimate is arrived at by means of a lattice QCD simulation of the polarized proton matrix element of the anomaly, F[sub [mu][nu

  13. Physics at an upgraded Fermilab proton driver

    Energy Technology Data Exchange (ETDEWEB)

    Geer, S.; /Fermilab

    2005-07-01

    In 2004 the Fermilab Long Range Planning Committee identified a new high intensity Proton Driver as an attractive option for the future, primarily motivated by the recent exciting developments in neutrino physics. Over the last few months a physics study has developed the physics case for the Fermilab Proton Driver. The potential physics opportunities are discussed.

  14. LHC Availability 2017: Standard Proton Physics

    CERN Document Server

    Todd, Benjamin; Apollonio, Andrea; Walsh, David John; CERN. Geneva. ATS Department

    2017-01-01

    This document summarises the LHC machine availability for the period from restart to the end of standard proton physics in 2017. This covers the whole standard proton physics production period. This note has been produced and ratified by the Availability Working Group which has complied fault information for the period in question using the Accelerator Fault Tracker.

  15. Proton Therapy Research and Treatment Center

    Energy Technology Data Exchange (ETDEWEB)

    Goodnight, J.E. Jr. (University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center); Alonso, J.R. (Lawrence Berkeley Lab., CA (United States))

    1992-05-01

    This Grant proposal outlines the steps that will be undertaken to bring the UC Davis Proton Therapy Research and Treatment, known locally as the Proton Therapy Facility (PTF), through its design and construction phases. This application concentrates on the design phase of the PTF project.

  16. Electron and proton transport by NADPH oxidases

    Science.gov (United States)

    Demaurex, Nicolas; Petheö, Gábor L

    2005-01-01

    The NADPH oxidase is the main weapon of phagocytic white blood cells that are the first line of defence of our body against invading pathogens, and patients lacking a functional oxidase suffer from severe and recurrent infections. The oxidase is a multisubunit enzyme complex that transports electrons from cytoplasmic NADPH to molecular oxygen in order to generate superoxide free radicals. Electron transport across the plasma membrane is electrogenic and is associated with the flux of protons through voltage-activated proton channels. Both proton and electron currents can be recorded with the patch-clamp technique, but whether the oxidase is a proton channel or a proton channel modulator remains controversial. Recently, we have used the inside–out configuration of the patch-clamp technique to record proton and electron currents in excised patches. This approach allows us to measure the oxidase activity under very controlled conditions, and has provided new information about the enzymatic activity of the oxidase and its coupling to proton channels. In this chapter I will discuss how the unique characteristics of the electron and proton currents associated with the redox activity of the NADPH oxidase have extended our knowledge about the thermodynamics and the physiological regulation of this remarkable enzyme. PMID:16321802

  17. Proton radioactivity with analytically solvable potential

    Indian Academy of Sciences (India)

    been carried out to study the proton radioactivity from proton-rich nuclei [2]. The existing theoretical studies can be classified into two broad categories. In the first category different theoretical approaches are based on quantum mechanical foun- dation such as transmission through a potential barrier [3], distorted wave Born.

  18. Configuration Manual Polarized Proton Collider at RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Alekseev, I.; Allgower, C.; Bai, M.; Batygin, Y.; Bozano, L.; Brown, K.; Bunce, G.; Cameron, P.; Courant, E.; Erin, S.; Escallier, J.; Fischer, W.; Gupta, R.; Hatanka, K.; Huang, H.; Imai, K.; Ishihara, M.; Jain, A.; Kanavets, V.; Katayama, T.; Kawaguchi, T.; Kelly, E.; Kurita, K.; Lee, S. Y.; Luccio, A.; MacKay, W. W.; Mahler, G.; Makdisi, Y.; Mariam, F.; McGahern, W.; Morgan, G.; Muratore, J.; Okamura, M.; Peggs, S.; Pilat, F.; Ptitsin, V.; Ratner, L.; Roser, T.; Saito, N.; Satoh, H.; Shatunov, Y.; Spinka, H.; Svirida, D.; Syphers, M.; Tepikian, S.; Tominaka, T.; Tsoupas, N.; Underwood, D.; Vasiliev, A.; Wanderer, P.; Willen, E.; Wu, H.; Yokosawa, A.; Zelenski, A.

    2006-01-01

    In this report we present our design to accelerate and store polarized protons in RHIC, with the level of polarization, luminosity, and control of systematic errors required by the approved RHIC spin physics program. We provide an overview of the physics to be studied using RHIC with polarized proton beams, and a brief description of the accelerator systems required for the project.

  19. CONFIGURATION MANUAL POLARIZED PROTON COLLIDER AT RHIC.

    Energy Technology Data Exchange (ETDEWEB)

    ROSER,T.; MACKAY,W.W.; ALEKSEEV,I.; BAI,M.; BROWN,K.; BUNCE,G.; CAMERON,P.; COURANT,E.; ET AL.

    2001-03-01

    In this report, the authors present their design to accelerate and store polarized protons in RHIC, with the level of polarization, luminosity, and control of systematic errors required by the approved RHIC spin physics program. They provide an overview of the physics to be studied using RHIC with polarized proton beams, and a brief description of the accelerator systems required for the project.

  20. [Interaction between clopidogrel and proton pump inhibitors

    NARCIS (Netherlands)

    Harmsze, A.M.; Boer, A. de; Boot, H.; Deneer, V.H.; Heringa, M.; Mol, P.G.; Schalekamp, T.; Verduijn, M.M.; Verheugt, F.W.A.; Comte, M. le

    2011-01-01

    The drug interaction between proton pump inhibitors and clopidogrel has been the subject of much study in recent years. Contradictory results regarding the effect of proton pump inhibitors on platelet reactivity and on clinical outcome in clopidogrel-treated patients have been reported in

  1. Action Research for Sustainability

    DEFF Research Database (Denmark)

    Egmose, Jonas

    to renew itself without eroding its own foundation of existence, it argues that since sustainability cannot be invented but only supported (or eroded) by science, we need to reframe science in the role of sustaining sustain-ability. Through analyses of a three year action research programme, aiming...... to provide local citizens with a greater say in the future of urban sustainability research, this book shows how action research can make important methodological contributions to processes of social learning between citizens and scientists by enabling free spaces in peoples everyday life and within academia......How can action research further new research orientations towards sustainability? This book, empirically situated in the field of upstream public engagement, involving local residents, researchers and practitioners in bottom-up processes deliberating on urban sustainability, answers this question...

  2. Action Research for Sustainability

    DEFF Research Database (Denmark)

    Egmose, Jonas

    to provide local citizens with a greater say in the future of urban sustainability research, this book shows how action research can make important methodological contributions to processes of social learning between citizens and scientists by enabling free spaces in peoples everyday life and within academia...... to renew itself without eroding its own foundation of existence, it argues that since sustainability cannot be invented but only supported (or eroded) by science, we need to reframe science in the role of sustaining sustain-ability. Through analyses of a three year action research programme, aiming......How can action research further new research orientations towards sustainability? This book, empirically situated in the field of upstream public engagement, involving local residents, researchers and practitioners in bottom-up processes deliberating on urban sustainability, answers this question...

  3. Sustainability in Business

    DEFF Research Database (Denmark)

    Tollin, Karin; Vej, Jesper

    2012-01-01

    How do companies integrate sustainability into their strategy and practices, and what factors explain their approach? In this paper a typology of sustainability strategies is presented as well as a conceptual framework relating sustainability at the company level to the functional level...... of marketing. The central contribution of the typology is a strategic and managerial view on sustainability. Furthermore, the typology shows that sustainability in business is enacted from different areas of competences and fields in the literature (e.g. supply chain management, corporate branding, value...... creation, product innovation and business model innovation). The empirical basis for the typology is an exploratory study of managers' mindsets about sustainability as strategy. Ten top managers involved with integrating sustainability within their companies have been interviewed. In order to reveal...

  4. Fur and Sustainability

    DEFF Research Database (Denmark)

    Skjold, Else; Csaba, Fabian

    2016-01-01

    This paper explores the notion of deeper luxury, which insists that 'real' luxury should involve sustainable practices in the production and consumption of luxury goods. It traces historical and recent developments in the field of fur, to understand the implications, uncertainties and ambiguities...... of luxury’s confrontation with sustainability. Considering fur in relation to future standards for luxury products, we raise questions about moral problematisation and justification of luxury in terms of sustainability. We first examine the encounter of luxury with sustainability and explain...... the significance of the notion of ‘deeper luxury’. After taking stock of the impact of sustainability on luxury and various directions in which sustainable luxury is evolving, we discuss concepts of sustainable development in relation to the history of moral problematisation of luxury. This leads to the case...

  5. Electron injection by relativistic protons in active galactic nuclei

    Science.gov (United States)

    Sikora, Marek; Kirk, John G.; Begelman, Mitchell C.; Schneider, Peter

    1987-01-01

    It is shown that protons with Lorentz factors larger than about 1,000,000 are cooled very rapidly by collisions with soft photons in the environment of an AGN. If the energy distribution of accelerated protons is sufficiently flat, then most of the energy contained in relativistic protons will be transformed to pairs, and then to radiation. Under these conditions, proton cooling due to p-gamma interactions is much more important than energy losses due to inelastic proton-proton collisions.

  6. Health and sustainability.

    Science.gov (United States)

    Kjӕrgård, Bente; Land, Birgit; Bransholm Pedersen, Kirsten

    2014-09-01

    In the present article, we explore how sustainable development strategies and health promotion strategies can be bridged. The concept of the 'duality of structure' is taken as our starting point for understanding the linkages between health promotion and sustainable development, and for uncovering the structural properties or conditions which either enable or constrain sustainable public health initiatives. We argue that strategies towards health promotion are not sufficiently integrated with strategies for sustainable development, and thus political strategies aimed at solving health problems or sustainability problems may cause new, undesired and unforeseen environmental or health problems. First, we explore how the relation between health and sustainability is articulated in international policy documents. Next, we develop a model for understanding the relation between health promotion and sustainability. Third, we use examples from agriculture and food production to illustrate that health and sustainability are mutually enabling and constraining. We conclude that while the renewed focus on food security and food inequalities has brought the health and sustainability dimensions of the food system onto the political agenda, the conceptualization of duality between health and sustainability could be a new platform for a critical and theoretical stance towards the market-oriented food system strategy. Thinking along the lines of duality means that the integration of health promotion strategies and sustainable development strategies cannot be based on an approach to integration in which either health or sustainability is given precedence over the other. From a duality perspective, integration means conceiving sustainability from a health perspective and health from a sustainability perspective. © The Author (2013). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Track Reconstruction and the Proton Radius Puzzle

    Science.gov (United States)

    Clark, Steven; Cline, Ethan; Gilman, Ron; MUSE Collaboration

    2017-09-01

    In 2010, Pohl et al. measured the proton charge radius to be 0.84184(67) fm using muonic hydrogen spectroscopy. This value differs about 5 σ from the CODATA proton radius from measurements with electrons. Other experiments with muons and electrons have confirmed the difference and the discrepancy has been termed the `Proton Radius Puzzle.' Currently there are no explanations for the puzzle. The MUon proton Scattering Experiment (MUSE) will make a significant measurement of the proton radius with muon scattering for the first time. The experiment tracks elastic scattering of electrons and muons off of liquid hydrogen. Particle tracks are reconstructed with track fitting software GenFit. Using a simulation of MUSE, GenFit has been determined to be proficient at track reconstruction. This project has been supported by funding from National Science Foundation Grant PHY-1560077.

  8. Proton conducting ceramic membranes for hydrogen separation

    Energy Technology Data Exchange (ETDEWEB)

    Elangovan, S [South Jordan, UT; Nair, Balakrishnan G [Sandy, UT; Small, Troy [Midvale, UT; Heck, Brian [Salt Lake City, UT

    2011-09-06

    A multi-phase proton conducting material comprising a proton-conducting ceramic phase and a stabilizing ceramic phase. Under the presence of a partial pressure gradient of hydrogen across the membrane or under the influence of an electrical potential, a membrane fabricated with this material selectively transports hydrogen ions through the proton conducting phase, which results in ultrahigh purity hydrogen permeation through the membrane. The stabilizing ceramic phase may be substantially structurally and chemically identical to at least one product of a reaction between the proton conducting phase and at least one expected gas under operating conditions of a membrane fabricated using the material. In a barium cerate-based proton conducting membrane, one stabilizing phase is ceria.

  9. Status of the Proton Engineering Frontier Project

    CERN Document Server

    Choi Byung Ho

    2005-01-01

    The Proton Engineering Frontier Project (PEFP) approved and launched by the Korean government in July 2002 includes a 100MeV proton linear accelerator development and a program for its utilization. The first phase of the project, running from 2002 to 2005, was the design of a 100MeV proton linear accelerator and a part of development to 20 MeV. This consists of a 50 keV proton injector, a 3 MeV radio frequency quadrupole (RFQ), and a 20MeV drift tube linac (DTL). The 50 keV injector and the 3 MeV RFQ has been installed and tested, and the 20 MeV DTL is being assembled and tuned for beam tests. At the same time, the utilization programs using the proton beam have been planned, and some are now under way. The status and progress of the project are reported in detail.

  10. A self-discharge model of Lithium-Sulfur batteries based on direct shuttle current measurement

    DEFF Research Database (Denmark)

    Knap, Vaclav; Stroe, Daniel Loan; Swierczynski, Maciej Jozef

    2016-01-01

    . A simple but comprehensive mathematical model of the Li-S battery cell self-discharge based on the shuttle current was developed and is presented. The shuttle current values for the model parameterization were obtained from the direct shuttle current measurements. Furthermore, the battery cell depth...

  11. Requirements for carnitine shuttle-mediated translocation of mitochondrial acetyl moieties to the yeast cytosol

    NARCIS (Netherlands)

    van Rossum, Harmen M.; Kozak, B.U.; Niemeijer, M.S.; Dykstra, James C.; Luttik, M.A.H.; Daran, J.G.; van Maris, A.J.A.; Pronk, J.T.

    2016-01-01

    In many eukaryotes, the carnitine shuttle plays a key role in intracellular transport of acyl moieties. Fatty acidgrown Saccharomyces cerevisiae cells employ this shuttle to translocate acetyl units into their mitochondria. Mechanistically, the carnitine shuttle should be reversible, but previous

  12. High density scintillating glass proton imaging detector

    Science.gov (United States)

    Wilkinson, C. J.; Goranson, K.; Turney, A.; Xie, Q.; Tillman, I. J.; Thune, Z. L.; Dong, A.; Pritchett, D.; McInally, W.; Potter, A.; Wang, D.; Akgun, U.

    2017-03-01

    In recent years, proton therapy has achieved remarkable precision in delivering doses to cancerous cells while avoiding healthy tissue. However, in order to utilize this high precision treatment, greater accuracy in patient positioning is needed. An accepted approximate uncertainty of +/-3% exists in the current practice of proton therapy due to conversions between x-ray and proton stopping power. The use of protons in imaging would eliminate this source of error and lessen the radiation exposure of the patient. To this end, this study focuses on developing a novel proton-imaging detector built with high-density glass scintillator. The model described herein contains a compact homogeneous proton calorimeter composed of scintillating, high density glass as the active medium. The unique geometry of this detector allows for the measurement of both the position and residual energy of protons, eliminating the need for a separate set of position trackers in the system. Average position and energy of a pencil beam of 106 protons is used to reconstruct the image rather than by analyzing individual proton data. Simplicity and efficiency were major objectives in this model in order to present an imaging technique that is compact, cost-effective, and precise, as well as practical for a clinical setting with pencil-beam scanning proton therapy equipment. In this work, the development of novel high-density glass scintillator and the unique conceptual design of the imager are discussed; a proof-of-principle Monte Carlo simulation study is performed; preliminary two-dimensional images reconstructed from the Geant4 simulation are presented.

  13. Parametric trade studies on a Shuttle 2 launch system architecture

    Science.gov (United States)

    Stanley, Douglas O.; Talay, Theodore A.; Lepsch, Roger A.; Morris, W. Douglas; Naftel, J. Christopher; Cruz, Christopher I.

    1991-01-01

    A series of trade studies are presented on a complementary architecture of launch vehicles as a part of a study often referred to as Shuttle-2. The results of the trade studies performed on the vehicles of a reference Shuttle-2 mixed fleet architecture have provided an increased understanding of the relative importance of each of the major vehicle parameters. As a result of trades on the reference booster-orbiter configuration with a methane booster, the study showed that 60 percent of the total liftoff thrust should be on the booster and 40 percent on the orbiter. It was also found that the liftoff thrust to weight ratio (T/W) on the booster-orbiter should be 1.3. This leads to a low dry weight and still provides enough thrust to allow the design of a heavy lift architecture. As a result of another trade study, the dry weight of the reference booster-orbiter was chosen for a variety of operational considerations. Other trade studies on the booster-orbiter demonstrate that the cross feeding of propellant during boost phase is desirable and that engine-out capability from launch to orbit is worth the performance penalty. Technology assumptions made during the Shuttle-2 design were shown to be approx. equivalent to a 25 percent across the board weight reduction over the Space Shuttle technology. The vehicles of the Shuttle-2 architecture were also sized for a wide variety of payloads and missions to different orbits. Many of these same parametric trades were also performed on completely liquid hydrogen fueled fully reusable concepts. If a booster-orbiter is designed using liquid hydrogen engines on both the booster and orbiter, the total vehicle dry weight is only 3.0 percent higher than the reference dual-fuel booster-orbiter, and the gross weight is 3.8 percent less. For this booster-orbiter vehicle, a liftoff T/W of 1.3, a thrust of about 60 percent on the booster, and a Mach staging number of 3 all proved to be desirable. This modest dry weight increase for a

  14. A modified incremental shuttle run test for the determination of peak shuttle running speed and the prediction of maximal oxygen uptake.

    Science.gov (United States)

    Wilkinson, D M; Fallowfield, J L; Myers, S D

    1999-05-01

    The aim of this study was to determine the incidence of subject drop-out on a multi-stage shuttle run test and a modified incremental shuttle run test in which speed was increased by 0.014 m x s(-1) every 20-m shuttle to avoid the need for verbal speed cues. Analysis of the multi-stage shuttle run test with 208 elite female netball players and 381 elite male lacrosse players found that 13 (+/-3) players stopped after the first shuttle of each new level, in comparison with 5 (+/-2) players on any other shuttle. No obvious drop-out pattern was observed on the incremental shuttle run test with 273 male and 79 female undergraduate students. The mean difference between a test-retest condition (n = 20) for peak shuttle running speed (-0.03+/-0.01 m x s(-1)) and maximal heart rate (0.4+/-0.1 beats x min(-1)) on the incremental test showed no bias (P > 0.05). The 95% absolute confidence limits of agreement were+/-0.11 m x s(-1) for peak shuttle running speed and+/-5 beats min(-1) for maximal heart rate. The relationship (n = 27) between peak shuttle running speed on the incremental shuttle run test (4.22+/-0.14 m x s(-1)) and VO2max (59.0+/-1.7 ml kg(-1) x min(-1)) was r= 0.91 (Prun test may influence subject drop-out. The incremental shuttle run test shows no obvious drop-out patten and provides a valid estimate of VO2max.

  15. Proton induced luminescence of minerals

    Energy Technology Data Exchange (ETDEWEB)

    Calvo del Castillo, H.; Millan, A.; Calderon, T. [Depto. Geologia y Geoquimica, Universidad Autonoma de Madrid, Ctra. Colmenar, km. 15, 28049, Madrid (Spain); Beneitez, P. [Departamento Quimica Fisica Aplicada, Universidad Autonoma de Madrid Cantoblanco, Madrid (Spain); Ruvalcaba S, J.L. [lFUNAM, Circuito de la lnvestigacion Cientifica s/n, Ciudad Universitaria, 04510 Mexico D.F. (Mexico)

    2008-07-01

    This paper presents a summary of Ionoluminescence (IL) for several minerals commonly found in jewellery pieces and/or artefacts of historical interest. Samples including silicates and non-silicates (native elements, halide, oxide, carbonate and phosphate groups) have been excited with a 1.8 MeV proton beam, and IL spectra in the range of 200- 900 nm have been collected for each one using a fiber optic coupled spectrometer. Light emissions have been related to Cr{sup 3+}, Mn{sup 2+} and Pr{sup 3+} ions, as well as intrinsic defects in these minerals. Results show the potential of IL for impurity characterization with high detection limits, local symmetry studies, and the study of the origin of minerals. (Author)

  16. [What is sustainability science?].

    Science.gov (United States)

    Wu, Jian-Guo; Guo, Xiao-Chuan; Yang, Jie; Qian, Gui-Xia; Niu, Jian-Ming; Liang, Cun-Zhu; Zhang, Qing; Li, Ang

    2014-01-01

    Sustainability is the theme of our time and also the grandest challenge to humanity. Since the 1970s, the term, sustainable development, has frequently appeared in the scientific literature, governmental documents, media promotions for public goods, and commercial advertisements. However, the science that provides the theoretical foundation and practical guidance for sustainable development--sustainability science--only began to emerge in the beginning of the 21st century. Nevertheless, the field has rapidly developed in depth and expanded in scope during the past decade, with its core concepts and research methods coalescing. China, as the most populous country in the world and home to the philosophical root of sustainability science-the unity of man and nature, is obligated to take upon the challenge of our time, to facilitate global sustainability while pursuing the Chinese Dream, and to play a leading role in the development of sustainability science. Toward this grandiose goal, this paper presents the first Chinese introduction to sustainability science, which discusses its basic concepts, research questions, and future directions. Sustainability science is the study of the dynamic relationship between humans and the environment, particularly focusing on the vulnerability, robustness, resilience, and stability of the coupled human-environment system. It is a transdisciplinary science that integrates natural sciences with humanities and social sciences. It hinges on the environment-economy-society nexus, and merges basic and applied research. The key components of sustainability often change with time, place, and culture, and thus sustainability science needs to emphasize multi-scale studies in space and time, with emphasis on landscapes and regions over a horizon of 50 to 100 years. It needs to focus on the relationship between ecosystem services and human well-being, as influenced by biodiversity and ecosystem processes as well as climate change, land use

  17. decolonising sustainability: subverting and appropriating

    African Journals Online (AJOL)

    magnitude for environmental education. We can speak of sustainable development, sustainable economies, sustainable democracy, a sustainable world order, and sustainable modes of health maintenance, but when we turn to spiritual matters we are faced with the black hole of green· politics: what constitutes sustainable.

  18. The UV-VIS optical environment of the shuttle

    Science.gov (United States)

    Torr, M. R.

    1985-01-01

    During the Spacelab 1 shuttle mission, spectroscopic measurements were made of the atmospheric emissions over a broad wavelength range extending from the extreme ultraviolet to the near infrared. Those measurements were made under a variety of vehicle attitude and sunlight conditions. Superimposed on such spectra would be any features associated with the induced vehicle environment and its interaction with solar photons and the ambient neutral atmosphere and plasma. Various anomalies and unexpected features in the spectra from the perspective of possible shuttle-induced origins are discussed. The data indicate a dramatic cleanup of the vehicle environment over the course of the 10-day mission, a strong non-atmospheric red continuum underlying the spectra at night and at large angles to the velocity vector, and a variety of molecular band distributions which are not explained by the present understanding of the atmosphere.

  19. Mass-driver reaction engine as Shuttle upper-stage

    Science.gov (United States)

    Oneill, G. K.

    1977-01-01

    Optimization has been carried out on the design of a mass-driver intended for upgrading the Shuttle to geosynchronous and lunar-orbit capability. The machine accelerates 2,100 tons/yr of external tankage, in 14-gram segments, to exhaust velocities of 8,000-10,000 m/s. The resulting reaction force raises 1,700 tons/yr. of Shuttle payloads to high orbit, in two round trips. Exhaust velocity and thrust can be optimized for each mission segment. For a mission requiring an exhaust velocity of 8,000 m/sec, thrust is 560 newtons, power is 2.9 megawatts, and efficiency is 75%. Total electrical component mass including power supplies and waste-heat radiators is 89 tons. To insure that reaction mass does not constitute a hazard, segments may be in the form of powder, electrostatically dispersed after acceleration, and/or thrust may be vectored.

  20. Operational safety of FPSOs shuttle tanker collision risk summary report

    Energy Technology Data Exchange (ETDEWEB)

    Vinnem, J.E.

    2003-07-01

    This report presents a summary of some of the observations and recommendations made in the research project' Operational Safety of FPS0s financed by Esso Norge AS/ExxonMobil Upstream Research Company, Health and Safety Executive and Statoil, and with Navion ASA as a Technology Sponsor. The project is carried out jointly by NTNU and SINTEF, with Department of Marine Technology, NTNU as project responsible. The overall scope of the research project is to develop methodologies for risk assessment of FPSO vessels with particular emphasis on analysis of operational aspects. The scope of the last phase has on the other hand been to analyse in detail, using the previously developed approach, the collision risk between the FPSO and its shuttle tanker, during all phases of off-loading operations. This summary report is focused on the analysis of collision risk between the shuttle tanker and the FPSO. (author)

  1. Effects of radiation environment on reusable nuclear shuttle system

    Science.gov (United States)

    Lane, A. G.

    1972-01-01

    Parametric tradeoff analyses of a wide spectrum of alternate tank configurations to minimize both primary and secondary, direct and scattered radiation sources emanating from the NERVA are reported. The analytical approach utilizing point kernel techniques is described and detailed data are presented on the magnitude of neutron/gamma doses for different locations. Single-tank configurations utilizing smaller cone angles and end cap radii were found to minimize integral radiation levels, hence, stage shielding-weight penalties for shuttle missions. Hybrid configurations employing an upper tank with a reduced cone angle and end cap radius result in low integral payload doses primarily due to the increased separation distance caused by the elongation of the larger capacity upper tank. A preliminary radiation damage assessment is discussed of possible reusable nuclear shuttle materials, components, and subsystems, and the possible effects of the radiation environment on various phases of RNS mission operations.

  2. Flight Experiment Verification of Shuttle Boundary Layer Transition Prediction Tool

    Science.gov (United States)

    Berry, Scott A.; Berger, Karen T.; Horvath, Thomas J.; Wood, William A.

    2016-01-01

    Boundary layer transition at hypersonic conditions is critical to the design of future high-speed aircraft and spacecraft. Accurate methods to predict transition would directly impact the aerothermodynamic environments used to size a hypersonic vehicle's thermal protection system. A transition prediction tool, based on wind tunnel derived discrete roughness correlations, was developed and implemented for the Space Shuttle return-to-flight program. This tool was also used to design a boundary layer transition flight experiment in order to assess correlation uncertainties, particularly with regard to high Mach-number transition and tunnel-to-flight scaling. A review is provided of the results obtained from the flight experiment in order to evaluate the transition prediction tool implemented for the Shuttle program.

  3. OSS-1 - A pathfinder mission for space science on Shuttle

    Science.gov (United States)

    Neupert, W. M.

    1983-01-01

    On the third Shuttle flight (STS-3), the Orbiter carried a payload of nine scientific instruments. The payload was designated OSS-1 because the program was originaly managed by the Office of Space Science. The OSS-1 objectives are discussed, taking into account the Plasma Diagnostics Package, a study concerned with vehicle charging and potential, the Thermal Canister Experiment, the Solar Flare X-ray Polarimeter, the Solar Ultraviolet Spectral Irradiance Monitor, the study of the influence of weightlessness on lignification in developing plant seedlings, the Microabrasion Foil Experiment, the Contamination Monitor Package, and a study of the characteristics of the Shuttle/Spacelab induced atmosphere. The OSS-1 payload was launched on STS-3 on March 22, 1982.

  4. SMART SUSTAINABLE ISLANDS VS SMART SUSTAINABLE CITIES

    Directory of Open Access Journals (Sweden)

    D. N. Pantazis

    2017-09-01

    Full Text Available This paper has several aims: a the presentation of a critical analysis of the terms “smart sustainable cities” and “smart sustainable islands” b the presentation of a number of principles towards to the development methodological framework of concepts and actions, in a form of a manual and actions guide, for the smartification and sustainability of islands. This kind of master plan is divided in thematic sectors (key factors which concern the insular municipalities c the creation of an island’s smartification and sustainability index d the first steps towards the creation of a portal for the presentation of our smartification actions manual, together with relative resources, smart applications examples, and, in the near future the first results of our index application in a number of Greek islands and e the presentation of some proposals of possible actions towards their sustainable development and smartification for the municipalities - islands of Paros and Antiparos in Greece, as case studies.

  5. Self-sustained oscillations in nanoelectromechanical systems induced by Kondo resonance

    Science.gov (United States)

    Song, Taegeun; Kiselev, Mikhail N.; Kikoin, Konstantin; Shekhter, Robert I.; Gorelik, Leonid Y.

    2014-03-01

    We investigate the instability and dynamical properties of nanoelectromechanical systems represented by a single-electron device containing movable quantum dots attached to a vibrating cantilever via asymmetric tunnel contacts. The Kondo resonance in electron tunneling between the source and shuttle facilitates self-sustained oscillations originating from the strong coupling of mechanical and electronic/spin degrees of freedom. We analyze a stability diagram for the two-channel Kondo shuttling regime due to limitations given by the electromotive force acting on a moving shuttle, and find that the saturation oscillation amplitude is associated with the retardation effect of the Kondo cloud. The results shed light on possible ways to experimentally realize the Kondo-cloud dynamical probe by using high mechanical dissipation tunability as well as supersensitive detection of mechanical displacement.

  6. STS-70 Space Shuttle Mission Report - September 1995

    Science.gov (United States)

    Fricke, Robert W., Jr.

    1995-01-01

    The STS-70 Space Shuttle Program Mission Report summarizes the Payload activities as well as the Orbiter, External Tank (ET), Solid Rocket Booster (SRB), Reusable Solid Rocket Motor (RSRM), and the Space Shuttle main engine (SSME) systems performance during the seventieth flight of the Space Shuttle Program, the forty-fifth flight since the return-to-flight, and the twenty-first flight of the Orbiter Discovery (OV-103). In addition to the Orbiter, the flight vehicle consisted of an ET that was designated ET-71; three SSMEs that were designated as serial numbers 2036, 2019, and 2017 in positions 1, 2, and 3, respectively; and two SRBs that were designated 81-073. The RSRMs, designated RSRM-44, were installed in each SRB and were designated as 36OL044A for the left SRB, and 36OL044B for the right SRB. The primary objective of this flight was to deploy the Tracking and Data Relay Satellite-G/Inertial Upper Stage (TDRS-G/IUS). The secondary objectives were to fulfill the requirements of the Physiological and Anatomical Rodent Experiment/National Institutes of Health-Rodents (PARE/NIH-R); Bioreactor Demonstration System (BDS); Commercial Protein Crystal Growth (CPCG) experiment; Space Tissue Loss/National Institutes of Health - Cells (STL/NIH-C) experiment; Biological Research in Canisters (BRIC) experiment; Shuttle Amateur Radio Experiment-2 (SAREX-2); Visual Function Tester-4 (VFT-4); Hand-Held, Earth-Oriented, Real-Time, Cooperative, User-Friendly Location-Targeting and Environmental System (HERCULES); Microencapsulation in Space-B (MIS-B) experiment; Window Experiment (WINDEX); Radiation Monitoring Equipment-3 (RME-3); and the Military Applications of Ship Tracks (MAST) payload.

  7. Modular heat pipe radiators for enhanced Shuttle mission capabilities

    Science.gov (United States)

    Alario, J.; Haslett, R.

    1979-01-01

    Current heat pipe radiator technology is reviewed and the results from three state-of-the-art hardware programs are summarized. Heat pipe radiators are shown to be an improvement over all-fluid loop panels for long duration space missions, when micrometeoroid survivability is important. Finally, several heat pipe radiator design concepts are presented which would enhance Shuttle mission capabilities by either extending mission life and/or augmenting heat rejection capability.

  8. RF environment survey of Space Shuttle related EEE frequency bands

    Science.gov (United States)

    Simpson, J.; Prigel, B.; Postelle, J.

    1977-01-01

    Radio frequency assignments within the continental United States in frequency bands between 121 MHz abd 65 GHz were surveyed and analyzed in order to determine current utilization of anticipated frequency bands for the shuttle borne electromagnetic environment experiment. Data from both government and nongovernment files were used. Results are presented in both narrative form and in histograms which show the total number of unclassified assignments versus frequency and total assigned power versus frequency.

  9. On the wings of a dream: The Space Shuttle

    Science.gov (United States)

    1988-01-01

    Described are the organization and some of the interests and missions of NASA, the Space Transportation System, the Space Shuttle orbiter Enterprise, astronaut training and clothing, being launched into space, living and working in weightlessness, extravehicular activity, and the return from space to Earth. The various aspects of living in space are treated in considerable detail. This includes how the astronauts prepare food, how they eat and drink, how they sleep, exercise, change clothes and handle personal hygiene when in space.

  10. Food and medical sample freezer kit concept for Shuttle

    Science.gov (United States)

    Copeland, R. J.; Jaax, J. R.; Proctor, B. W.

    1977-01-01

    A variety of food and storage of samples can be provided by a Space Shuttle Orbiter Freezer Kit. The proposed concept is an integrated package consisting of four -23 C (-10 F) storage compartments and a Stirling cycle refrigeration unit. The Stirling cycle mechanical refrigeration was selected over alternative systems for superior efficiency and safety. The trade-offs and a conceptual design of the system are presented.

  11. Shuttle Tethered Aerothermodynamics Research Facilty (STARFAC) instrumentation requirements

    Science.gov (United States)

    Wood, G. M.; Siemers, P. M.; Carlomagno, G. M.; Hoffman, J.

    1986-01-01

    The instrumentation requirements for the Shuttle Tethered Aerothermodynamic Research Facility (STARFAC) are presented. The typical physical properties of the terrestrial atmosphere are given along with representative atmospheric daytime ion concentrations and the equilibrium and nonequilibrium gas property comparison from a point away from a wall. STARFAC science and engineering measurements are given as are the TSS free stream gas analysis. The potential nonintrusive measurement techniques for hypersonic boundary layer research are outlined along with the quantitative physical measurement methods for aerothermodynamic studies.

  12. Oxidation resistant carbon-carbon composite for Space Shuttle application.

    Science.gov (United States)

    Rogers, D. C.; Seeger, J. W.; Shuford, D. M.

    1973-01-01

    An oxidation resistant carbon-carbon composite has been developed for use on the NASA Space Shuttle Orbiter Vehicle which can function on the high temperature surfaces to satisfy the 100 mission reuse capability requirement. This paper describes the design requirements, materials and processes developed, and the successful testing of simulated full-scale prototype hardware. Materials considerations are illustrated, including strength and oxidation testing, along with physical property determinations, characterizing the material over the predicted temperature range of use.

  13. Space shuttle contamination due to backflow from control motor exhaust

    Science.gov (United States)

    Robertson, S. J.; Chan, S. T. K.; Lee, A. L.

    1976-01-01

    Spacecraft contamination of the space shuttle orbiter and accompanying Spacelab payloads is studied. The scattering of molecules from the vernier engines and flash evaporator nozzle after impingement on the orbiter wing surfaces, and the backflow of molecules out of the flash evaporator nozzle plume flow field due to intermolecular collisions in the plume are the problems discussed. A method was formulated for dealing with these problems, and detailed results are given.

  14. The Digital Space Shuttle, 3D Graphics, and Knowledge Management

    Science.gov (United States)

    Gomez, Julian E.; Keller, Paul J.

    2003-01-01

    The Digital Shuttle is a knowledge management project that seeks to define symbiotic relationships between 3D graphics and formal knowledge representations (ontologies). 3D graphics provides geometric and visual content, in 2D and 3D CAD forms, and the capability to display systems knowledge. Because the data is so heterogeneous, and the interrelated data structures are complex, 3D graphics combined with ontologies provides mechanisms for navigating the data and visualizing relationships.

  15. A Shuttle based laser system for space communication

    Science.gov (United States)

    Fitzmaurice, Michael W.; Bruno, Ronald C.

    1988-01-01

    A key element of NASA-Goddard's plan for future laser space communications is the Space Shuttle-based Laser Technology Experiments Facility (LTEF), which will be designed to communicate with a cooperative laser system under development for the Advanced Communication Technology Satellite (ACTS) and will conduct a comprehensive set of acquisition, tracking, and communication experiments. Attention is presently given to the challenges faced by designers in achieving LTEF acquisition of the ACTS downlink beacon laser.

  16. Sustainable Building Operation

    DEFF Research Database (Denmark)

    Jensen, Jesper Ole

    2009-01-01

    Energy-savings in the existing building stock have becomes a main goal in national and international policies. Often focus is on building-renovations, whereas the potential of sustainable building operation to a large extent has been neglected. Nevertheless, international research as well...... as practical experiences from Danish housing estates indicates that there are large potentials for energy savings by focusing on the operation of the buildings. We suggest that in order to achieve sustainability in the existing housing, renovation and operations should be seen as integrated parts...... and that sustainable building operation can pave the way for sustainable building renovation. This paper discusses the use of sustainability building operation in Danish housing estates: Which tools, methods and technologies is being used, where are the barriers and where are the potentials? We define sustainable...

  17. Health and Sustainability

    DEFF Research Database (Denmark)

    Land, Birgit; Pedersen, Kirsten Bransholm; Kjærgård, Bente

    2014-01-01

    In the present article, we explore how sustainable development strategies and health promotion strategies can be bridged. The concept of the ‘duality of structure’ is taken as our starting point for understanding the linkages between health promotion and sustainable development, and for uncovering...... the structural properties or conditions which either enable or constrain sustainable public health initiatives. We argue that strategies towards health promotion are not sufficiently integrated with strategies for sustainable development, and thus political strategies aimed at solving health problems...... or sustainability problems may cause new, undesired and unforeseen environmental or health problems. First, we explore how the relation between health and sustainability is articulated in international policy documents. Next, we develop a model for understanding the relation between health promotion...

  18. Sustainability and Entrepreneurial Action

    DEFF Research Database (Denmark)

    Korsgaard, Steffen T.; Anderson, Alistair

    Abstract Objectives - This paper explores how entrepreneurial action can lead to environmental sustainability. It builds on the assumption that the creation of sustainble practices is one of the most important challenges facing the global society, and that entrepreneurial action is a vital...... instrument in the pursuit of sustainability.  Prior Work - Extant literature identifies two main approaches to sustainable entrepreneurship. (i) traditional exploitation of environmentally relevant opportunities and (ii) institutional entrepreneurship creating opportunities. We identify a novel form......: resource oriented sustainable entrepreneurial action.  Approach - The paper uses a case study approach to build deeper theoretical knowledge of environmentally sustainable entrepreneurship.  Results - The paper identifies and analyses a distinct form of sustainable entrepreneurship -  resource oriented...

  19. At Home with Sustainability

    DEFF Research Database (Denmark)

    Hale, Lara

    2018-01-01

    of default rules in subconscious decision-making, this research finds that, ultimately, awareness drives the demand necessary for the creation of sustainable consumption. Whereas direct appeal to individuals has a disappointing level of influence on sustainability choices, it is understood that green......-fuel-based energy. To act otherwise requires additional effort and is less likely. Motivated by a need to understand how defaults might bridge standards and sustainable consumption, I investigate how organizational processes potentially lead from standardized green default rules to individual awareness that can...... spread and facilitate sustainable consumption. This paper examines the Active House sustainable building demonstrations in Europe in order to understand how (1) communications and market creation and (2) responsible, user-centered experimentation are organized to move from defaults to sustainable...

  20. ICT innovations for sustainability

    CERN Document Server

    Aebischer, Bernard

    2015-01-01

    ICT Innovations for Sustainability is an investigation of how information and communication technology can contribute to sustainable development. It presents clear definitions of sustainability, suggesting conceptual frameworks for the positive and negative effects of ICT on sustainable development. It reviews methods of assessing the direct and indirect impact of ICT systems on energy and materials demand, and examines the results of such assessments. In addition, it investigates ICT-based approaches to supporting sustainable patterns of production and consumption, analyzing them at various levels of abstraction – from end-user devices, Internet infrastructure, user behavior, and social practices to macro-economic indicators.   Combining approaches from Computer Science, Information Systems, Human-Computer Interaction, Economics, and Environmental Sciences, the book presents a new, holistic perspective on ICT for Sustainability (ICT4S). It is an indispensable resource for anyone working in the area of ICT...

  1. Sustainability and substitutability.

    Science.gov (United States)

    Fenichel, Eli P; Zhao, Jinhua

    2015-02-01

    Developing a quantitative science of sustainability requires bridging mathematical concepts from fields contributing to sustainability science. The concept of substitutability is central to sustainability but is defined differently by different fields. Specifically, economics tends to define substitutability as a marginal concept while fields such as ecology tend to focus on limiting behaviors. We explain how to reconcile these different views. We develop a model where investments can be made in knowledge to increase the elasticity of substitution. We explore the set of sustainable and optimal trajectories for natural capital extraction and built and knowledge capital accumulation. Investments in substitutability through knowledge stock accumulation affect the value of natural capital. Results suggest that investing in the knowledge stock, which can enhance substitutability, is critical to desirable sustainable outcomes. This result is robust even when natural capital is not managed optimally. This leads us to conclude that investments in the knowledge stock are of first order importance for sustainability.

  2. Sustainable Concrete Technology

    Directory of Open Access Journals (Sweden)

    Sim J.

    2015-12-01

    Full Text Available The growing concern over global warming and significant ecological changes requires sustainable development in all fields of science and technology. Concrete not only consumes huge amount of energy and natural sources, but also emits large amount of CO2, mainly due to the production of cement. It is evident that such large amount of concrete production has put significant impact on the energy, resource, environment, and ecology of the society. Hence, how to develop the concrete technology in a sustainable way has become a significant issue. In this paper, some of Korean researches for sustainable development of concrete are presented. These are sustainable strengthening for deteriorated concrete structure, sustainable reinforcement of new concrete structure, sustainable concrete using recycled aggregate and supplementary cementing materials and finally application of each technique to precast concrete.

  3. Dielectron production in proton-proton collisions with ALICE

    Energy Technology Data Exchange (ETDEWEB)

    Koehler, Markus Konrad

    2015-10-01

    Ultrarelativistic hadron collisions, such as delivered since a couple of years at the Large Hadron Collider (LHC), provide new insights into the properties of strongly interacting matter at high temperatures and densities, which is expected to have existed a few of a millionth seconds after the big bang. Electromagnetic probes, such as leptons and photons, are emitted during the entire collision. Since they do not undergo strong interactions, they reflect the entire evolution of the collision. Pairs of leptons, so called dileptons, have the advantage compared to real photons, that they do not only carry momentum, but also have a non-zero invariant mass. The invariant mass spectrum of dileptons is a superposition of several components and allows to address different characteristics of the medium. To understand dielectron production in heavy-ion collisions, reference measurements in proton-proton (pp) collisions are necessary. pp collisions reflect the vacuum contribution of the particles produced in heavy-ion collisions. The analysis of pp collisions is an essential step towards the extraction of medium influences on the vector meson spectral functions and the thermal radiation in heavy-ion collisions. In this thesis, the production of electron-positron pairs (dielectrons) in pp collisions at a collision energy of 7 TeV in the ALICE central barrel is analysed. ALICE has unique particle identification capabilities at low momentum. Electrons and positrons are identified with a high purity and combined to pairs. The invariant mass distribution of dielectrons is corrected for detector effects and the selection criteria in the analysis with Monte Carlo simulations. The dielectron invariant mass spectrum of known hadronic sources is calculated based on the cross sections measured in other decay channels using the known decay kinematics. This so called hadronic cocktail represents the dielectron spectrum at the moment of kinematic freeze-out and can be compared to the

  4. Proton induced defect formation in quartz glasses

    Energy Technology Data Exchange (ETDEWEB)

    Gulamova, R.R.; Gasanov, E.M.; Alimov, R. [Uzbekian AS, Tashkent (Uzbekistan). Inst. of Nuclear Physics

    1996-12-31

    The contributions of ionization energy losses and elastic collisions to radiation induced defect formation along the proton track were considered in quartz glasses irradiated by protons with different energies. It is shown that on a larger part of the proton track the color and luminescence center formation by means of recharging of the native defects is due to the ionization energy losses. Generation of structural defects like displaced atoms and their vacancies by elastic collisions with protons and recoil atoms dominates for proton energies < 5 MeV. At proton energies > 10 MeV the color and luminescence center formation due to ionization energy losses prevails, and generation of the alumina-alkaline centers, causing an increase of the optical absorption at 550 nm and the thermoluminescence peak at 360 C and a band at 460 nm, occurs. At the proton energies E{sub p} < 10 MeV generation of the displaced atoms and their vacancies by elastic collisions dominates, leading to an increase of the E{prime}-centers and to the destruction and transformation of the alumina-alkaline centers.

  5. Absolute proton affinity of some polyguanides

    Science.gov (United States)

    Maksic; Kovacevic

    2000-06-02

    The problem of the absolute proton affinity (APA) of some polyguanides is addressed by the MP2(fc)/6-311+G//HF/6-31G theoretical model. It is shown that the linear chain polyguanides exhibit increased basicity as a function of the number of guanide subunits. However, the saturation effect yields an asymptotic APA value of 254 kcal/mol. Branched polyguanides on the other hand have higher APAs than their linear counterparts. The largest proton affinity is found in a doubly bifurcated heptaguanide, being as high as 285 kcal/mol, thus potentially representing one of the strongest organic bases. Finally, it is found that all polyguanides protonate at imino nitrogen atoms, since they are apparently susceptible the most to the proton attack. The origin of their very high intrinsic basicity is traced down to a dramatic increase in the resonance interaction of the corresponding conjugate bases. For instance, the increase in the resonance energy in the protonated guanidine is estimated to be in a range of 24-27 kcal/mol, which is higher than the aromatic stabilization in benzene. The proton affinity of some polycyclic guanides including Schwesinger proton sponge and porphine is briefly discussed.

  6. Nerve Conduction Through Dendrites via Proton Hopping.

    Science.gov (United States)

    Kier, Lemont B

    2017-01-01

    In our previous studies of nerve conduction conducted by proton hopping, we have considered the axon, soma, synapse and the nodes of Ranvier. The role of proton hopping described the passage of information through each of these units of a typical nerve system. The synapse projects information from the axon to the dendrite and their associated spines. We have invoked the passage of protons via a hopping mechanism to illustrate the continuum of the impulse through the system, via the soma following the dendrites. This is proposed to be a continuum invoked by the proton hopping method. With the proposal of the activity through the dendrites, via proton hopping, a complete model of the nerve function is invoked. At each step to the way, a water pathway is present and is invoked in the proposed model as the carrier of the message via proton hopping. The importance of the dendrites is evident by the presence of a vast number of spines, each possessing the possibility to carry unique messages through the nervous system. With this model of the role of dendrites, functioning with the presence of proton hopping, a complete model of the nerve system is presented. The validity of this model will be available for further studies and models to assess it's validity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  7. Hubble Servicing Challenges Drive Innovation of Shuttle Rendezvous Techniques

    Science.gov (United States)

    Goodman, John L.; Walker, Stephen R.

    2009-01-01

    Hubble Space Telescope (HST) servicing, performed by Space Shuttle crews, has contributed to what is arguably one of the most successful astronomy missions ever flown. Both nominal and contingency proximity operations techniques were developed to enable successful servicing, while lowering the risk of damage to HST systems, and improve crew safety. Influencing the development of these techniques were the challenges presented by plume impingement and HST performance anomalies. The design of both the HST and the Space Shuttle was completed before the potential of HST contamination and structural damage by shuttle RCS jet plume impingement was fully understood. Relative navigation during proximity operations has been challenging, as HST was not equipped with relative navigation aids. Since HST reached orbit in 1990, proximity operations design for servicing missions has evolved as insight into plume contamination and dynamic pressure has improved and new relative navigation tools have become available. Servicing missions have provided NASA with opportunities to gain insight into servicing mission design and development of nominal and contingency procedures. The HST servicing experiences and lessons learned are applicable to other programs that perform on-orbit servicing and rendezvous, both human and robotic.

  8. Space Shuttle Meteoroid and Orbital Debris Threat Assessment Procedure

    Science.gov (United States)

    Hyde, J.; Christiansen, E.

    Prior to each shuttle mission, Meteoroid and orbital Debris (M/OD) threat assessments are performed to determine the critical penetration risk for the orbiter vehicle, the radiator tube leak risk &the window replacement risk. Mission parameters, such as vehicle attitude, exposure time and altitude are used as inputs for the assessment. The assessments are performed using the BUMPER computer code at the NASA/JSC Hypervelocity Impact Technology Facility (HITF). An M/OD risk analysis is typically performed in support of orbiter Cargo Integration Reviews (CIR) and Flight Readiness Reviews (FRR). Three types of M/OD risk are assessed. The most important involves the calculation of "critical" penetration risk, defined as penetrations that may result in the catastrophic loss of vehicle and crew. Critical failure criteria have been established though detailed engineering evaluations by NASA and Boeing. The radiator assessment is concerned with premature end-of- mission due to loss of a coolant loop. The window assessment is a postflight maintenance and logistics issue. The result s are provided to the Space Shuttle Vehicle Engineering Office (MV) the Space and Life Science Directorate (SA) at JSC. This paper will document the inputs used in the critical penetration analysis for CIR, FRR, and post-flight assessments, it will also serve as a reference for the Space Shuttle Orbiter finite element model (FEM) surface property definitions that are used in M/OD threat assessments.

  9. Status of Thermal NDT of Space Shuttle Materials at NASA

    Science.gov (United States)

    Cramer, K. Elliott; Winfree, William P.; Hodges, Kenneth; Koshti, Ajay; Ryan, Daniel; Reinhardt, Walter W.

    2007-01-01

    Since the Space Shuttle Columbia accident, NASA has focused on improving advanced NDE techniques for the Reinforced Carbon-Carbon (RCC) panels that comprise the orbiter s wing leading edge and nose cap. Various nondestructive inspection techniques have been used in the examination of the RCC, but thermography has emerged as an effective inspection alternative to more traditional methods. Thermography is a non-contact inspection method as compared to ultrasonic techniques which typically require the use of a coupling medium between the transducer and material. Like radiographic techniques, thermography can inspect large areas, but has the advantage of minimal safety concerns and the ability for single-sided measurements. Details of the analysis technique that has been developed to allow insitu inspection of a majority of shuttle RCC components is discussed. Additionally, validation testing, performed to quantify the performance of the system, will be discussed. Finally, the results of applying this technology to the Space Shuttle Discovery after its return from the STS-114 mission in July 2005 are discussed.

  10. PEMBELAJARAN LARI CEPAT DENGAN MENGGUNAKAN MODIFIKASI SHUTTLE RUN

    Directory of Open Access Journals (Sweden)

    Suharjo

    2015-09-01

    Full Text Available The purpose of this study was to determine "Is Modified Shuttle Run can improve learning outcomes Elementary School fifth grade students Cenggini 02 Subdistrict Balapulang Tegal 2014". This research method is a class action research by using two cycles, each cycle consisting of four stages, namely planning, tindakkan, observation and action planning refleksi..Pada second cycle associated with the results achieved in the first cycle acts as an improvement efforts of the cycle. The subjects of this study were fifth grade students of elementary Negri Cenggini 02. Research conducted includes three domains, namely affective, cognitive and psychomotor addition to the observations made during the process of the learning process takes place. The results showed the affective, cognitive and psychomotor well categorized shows that the learning outcomes quick run using a modified shuttle run a positive impact as seen on mastery learning outcomes of students who exceed the predetermined KKM 75 In the first cycle the average value of students 75 , 71 in the second cycle the average value of 78.60 students, mastery learning in the first cycle reaches 64.29%, while in the second cycle reaches 92.86% mastery learning .mean mastery learning students has increased by 28.57%. It is concluded that learning to run faster by using a modified shuttle run has a positive effect, which can increase student interest and motivation to learn.

  11. Animation graphic interface for the space shuttle onboard computer

    Science.gov (United States)

    Wike, Jeffrey; Griffith, Paul

    1989-01-01

    Graphics interfaces designed to operate on space qualified hardware challenge software designers to display complex information under processing power and physical size constraints. Under contract to Johnson Space Center, MICROEXPERT Systems is currently constructing an intelligent interface for the LASER DOCKING SENSOR (LDS) flight experiment. Part of this interface is a graphic animation display for Rendezvous and Proximity Operations. The displays have been designed in consultation with Shuttle astronauts. The displays show multiple views of a satellite relative to the shuttle, coupled with numeric attitude information. The graphics are generated using position data received by the Shuttle Payload and General Support Computer (PGSC) from the Laser Docking Sensor. Some of the design considerations include crew member preferences in graphic data representation, single versus multiple window displays, mission tailoring of graphic displays, realistic 3D images versus generic icon representations of real objects, the physical relationship of the observers to the graphic display, how numeric or textual information should interface with graphic data, in what frame of reference objects should be portrayed, recognizing conditions of display information-overload, and screen format and placement consistency.

  12. Space Shuttle Day-of-Launch Trajectory Design and Verification

    Science.gov (United States)

    Harrington, Brian E.

    2010-01-01

    A top priority of any launch vehicle is to insert as much mass into the desired orbit as possible. This requirement must be traded against vehicle capability in terms of dynamic control, thermal constraints, and structural margins. The vehicle is certified to a specific structural envelope which will yield certain performance characteristics of mass to orbit. Some envelopes cannot be certified generically and must be checked with each mission design. The most sensitive envelopes require an assessment on the day-of-launch. To further minimize vehicle loads while maximizing vehicle performance, a day-of-launch trajectory can be designed. This design is optimized according to that day s wind and atmospheric conditions, which will increase the probability of launch. The day-of-launch trajectory verification is critical to the vehicle's safety. The Day-Of-Launch I-Load Uplink (DOLILU) is the process by which the Space Shuttle Program redesigns the vehicle steering commands to fit that day's environmental conditions and then rigorously verifies the integrated vehicle trajectory's loads, controls, and performance. The Shuttle methodology is very similar to other United States unmanned launch vehicles. By extension, this method would be similar to the methods employed for any future NASA launch vehicles. This presentation will provide an overview of the Shuttle's day-of-launch trajectory optimization and verification as an example of a more generic application of dayof- launch design and validation.

  13. Coordinating "Execute" Data for ISS and Space Shuttle

    Science.gov (United States)

    Whitney, Greg; Melendrez, David; Hadlock, Jason

    2010-01-01

    The Joint Execute Package Development and Integration tool is a Web utility program that provides an integrated capability to generate and manage messages and execute package data for members of a space shuttle and the International Space Station (ISS). (An execute package consists of flight plans, short-term plans, procedure updates, data needed to operate the space-shuttle and ISS systems, in-flight maintenance procedures, inventory-stowage data, software upgrades, flight notes, scripts for publicized events, and other instructions.) This program is a third-generation "execute"-package Web tool, built on experience gained from two programs used previously to support realtime operations. This program provides integration and synchronization between the space-shuttle and ISS teams during joint operations. Hundreds of messages per week must be uplinked as "joint" messages; that is, messages for crewmembers of both spacecraft. The program includes configuration-management components that ensure that the same message goes to both crews and spacecraft, effectively eliminating the potential for error in manual direction of messages. The program also controls the format and layout of the crews Web pages, ensuring consistency between uplinks. If the crews Web pages were edited manually, hyperlink and formatting errors would be common.

  14. Sustainable fashion: New approaches

    OpenAIRE

    Niinimäki, Kirsi

    2013-01-01

    This publication is intended to be used as a source of inspiration for designers and companies, and all stakeholders whose interest lies in the area of sustainable fashion. While the strategies for sustainability are complex and approaches are many, this publication presents only a few ways to approach sustainable fashion. I hope the publication offers inspiration on how to make positive change in current practices and how to effect new mindsets, creating transformative fashion. Theoretica...

  15. Education for sustainable development

    DEFF Research Database (Denmark)

    Breiting, Søren

    2009-01-01

     An introduction to the idea of sustainable development (SD) and education for sustainable development (ESD) with reference to the international Decade for Education for Sustainable Development . The chapter includes a focus on conflicting interests between present and future generations related...... to the use of natural resources and other matters, and how that kind of issues can be dealt with in education as ESD....

  16. A highly sustainable house

    OpenAIRE

    Cordero, Raúl; Mercader-Moyano, Pilar (Coordinador)

    2017-01-01

    A sustainable house is capable of generating and self-sustaining energy by itself to function autonomously, that is to say, without depending on external supply networks. That is possible by supplying the internal energy consumption through renewable energy. This work describes and analyzes the construction of a sustainable house in Paute, Ecuador. The goal of this house was to achieve selfsustainability in several aspects such as construction techniques, creative and functi...

  17. Sustainability Assessment Circle

    OpenAIRE

    Schlör, H.; Hake, J.-Fr.

    2015-01-01

    Since the nineteen seventies, science and society have been discussing the worldwide ecological, economic, and social problems caused by industrialization and globalization. Sustainable development is perceived as a strategy for coping with these problems. The Rio +20 conference in 2012 confirmed the sustainability concept and introduced the green economy and the life cycle sustainable assessment as its implementation and operationalization strategy and tool.In the following, we will demonstr...

  18. Investigation of Proton Focusing and Conversion Efficiency for Proton Fast Ignition

    Science.gov (United States)

    Bartal, Teresa Jean

    Recent advances in generating high energy (> 50 MeV) protons from intense laser-matter interactions has opened up new areas of research, with applications in radiography, high energy density physics, and ion-proton beam fast ignition (FI). The ability to focus the proton beam has made these applications more attractive. Fast ignition (FI) is an evolved concept of conventional inertial confinement fusion (ICF). In proton FI, a collimated beam of protons is used to deliver the necessary ignition energy to the compressed Deuterium-Tritium (DT) fuel capsule instead of the original concept of a beam composed of relativistic electrons. In cone-guided FI, a cone is embedded into the side of the fuel capsule where the proton source foil is placed within the cone. The cone provides a clear path to the dense core and protects the proton source foil from radiation during the compression of the capsule. The proton source foil is a segment of a hemispherical shell target used to help focus the proton beam to the core to spark ignition. The viability of proton FI requires focusing of the generated proton beam to a 40 mum spot at the compressed fuel and a laser to proton conversion efficiency of ˜15%. Here, proton focusing and the laser to proton conversion efficiency are investigated using flat foils and hemispherical shell targets. Experiments were conducted on the 200 TW short pulse laser at Los Alamos Laboratory. The 1053 nm laser pulse delivered 70--80 J on target in 500--600 fs focused by an f/8 parabolic mirror. The generated proton beam from the target was examined by placing a mesh downstream of the target, which the proton beam would pass though and then imaged with a pack of radiochromic film (RCF). A 3D ray-tracing technique was developed to determine the focal position and focal spot size of the generated proton beam by tracing the proton trajectories from the image of the mesh collected by the RCF back through the mesh to the central axis. The focal position

  19. Sustainability assessment and complementarity

    Directory of Open Access Journals (Sweden)

    Hugo F. Alrøe

    2016-03-01

    Full Text Available Sustainability assessments bring together different perspectives that pertain to sustainability to produce overall assessments, and a wealth of approaches and tools have been developed in the past decades. However, two major problems remain. The problem of integration concerns the surplus of possibilities for integration; different tools produce different assessments. The problem of implementation concerns the barrier between assessment and transformation; assessments do not lead to the expected changes in practice. We aim to analyze issues of complementarity in sustainability assessment and transformation as a key to better handling the problems of integration and implementation. Based on a generalization of Niels Bohr's complementarity from quantum mechanics, we have identified two forms of complementarity in sustainability assessment, observer stance complementarity and value complementarity. Unlike many other problems of sustainability assessment, complementarity is of a fundamental character connected to the very conditions for observation. Therefore, complementarity cannot be overcome methodologically, only handled better or worse. Science is essential to the societal goal of sustainability, but these issues of complementarity impede the constructive role of science in the transition to more sustainable structures and practices in food systems. The agencies of sustainability assessment and transformation need to be acutely aware of the importance of different perspectives and values and the complementarities that may be connected to these differences. An improved understanding of complementarity can help to better recognize and handle issues of complementarity. These deliberations have relevance not only for sustainability assessment, but more generally for transdisciplinary research on wicked problems.

  20. Predicting Sustainable Work Behavior

    DEFF Research Database (Denmark)

    Hald, Kim Sundtoft

    2013-01-01

    . Employee characteristics and general attitudes towards safety and work condition are included in the extended model. A survey was handed out to 654 employees in Chinese factories. This research contributes by demonstrating how employee- characteristics and general attitudes towards safety and work...... condition influence their sustainable work behavior. A new definition of sustainable work behavior is proposed.......Sustainable work behavior is an important issue for operations managers – it has implications for most outcomes of OM. This research explores the antecedents of sustainable work behavior. It revisits and extends the sociotechnical model developed by Brown et al. (2000) on predicting safe behavior...