Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

International Nuclear Information System (INIS)

Sanità, Patrizia; Capulli, Mattia; Teti, Anna; Galatioto, Giuseppe Paradiso; Vicentini, Carlo; Chiarugi, Paola; Bologna, Mauro; Angelucci, Adriano

2014-01-01

Cancer cell adopts peculiar metabolic strategies aimed to sustain the continuous proliferation in an environment characterized by relevant fluctuations in oxygen and nutrient levels. Monocarboxylate transporters MCT1 and MCT4 can drive such adaptation permitting the transport across plasma membrane of different monocarboxylic acids involved in energy metabolism. Role of MCTs in tumor-stroma metabolic relationship was investigated in vitro and in vivo using transformed prostate epithelial cells, carcinoma cell lines and normal fibroblasts. Moreover prostate tissues from carcinoma and benign hypertrophy cases were analyzed for individuating clinical-pathological implications of MCT1 and MCT4 expression. Transformed prostate epithelial (TPE) and prostate cancer (PCa) cells express both MCT1 and MCT4 and demonstrated variable dependence on aerobic glycolysis for maintaining their proliferative rate. In glucose-restriction the presence of L-lactate determined, after 24 h of treatment, in PCa cells the up-regulation of MCT1 and of cytochrome c oxidase subunit I (COX1), and reduced the activation of AMP-activated protein kinase respect to untreated cells. The blockade of MCT1 function, performed by si RNA silencing, determined an appreciable antiproliferative effect when L-lactate was utilized as energetic fuel. Accordingly L-lactate released by high glycolytic human diploid fibroblasts WI-38 sustained survival and growth of TPE and PCa cells in low glucose culture medium. In parallel, the treatment with conditioned medium from PCa cells was sufficient to induce glycolytic metabolism in WI-38 cells, with upregulation of HIF-1a and MCT4. Co-injection of PCa cells with high glycolytic WI-38 fibroblasts determined an impressive increase in tumor growth rate in a xenograft model that was abrogated by MCT1 silencing in PCa cells. The possible interplay based on L-lactate shuttle between tumor and stroma was confirmed also in human PCa tissue where we observed a positive

Catalytic mechanisms of direct pyrrole synthesis via dehydrogenative coupling mediated by PNP-Ir or PNN-Ru pincer complexes: Crucial role of proton-transfer shuttles in the PNP-Ir system

KAUST Repository

Qu, Shuanglin

2014-04-02

Kempe et al. and Milstein et al. have recently advanced the dehydrogenative coupling methodology to synthesize pyrroles from secondary alcohols (e.g., 3) and β-amino alcohols (e.g., 4), using PNP-Ir (1) and PNN-Ru (2) pincer complexes, respectively. We herein present a DFT study to characterize the catalytic mechanism of these reactions. After precatalyst activation to give active 1A/2A, the transformation proceeds via four stages: 1A/2A-catalyzed alcohol (3) dehydrogenation to give ketone (11), base-facilitated C-N coupling of 11 and 4 to form an imine-alcohol intermediate (18), base-promoted cyclization of 18, and catalyst regeneration via H2 release from 1R/2R. For alcohol dehydrogenations, the bifunctional double hydrogen-transfer pathway is more favorable than that via β-hydride elimination. Generally, proton-transfer (H-transfer) shuttles facilitate various H-transfer processes in both systems. Notwithstanding, H-transfer shuttles play a much more crucial role in the PNP-Ir system than in the PNN-Ru system. Without H-transfer shuttles, the key barriers up to 45.9 kcal/mol in PNP-Ir system are too high to be accessible, while the corresponding barriers (<32.0 kcal/mol) in PNN-Ru system are not unreachable. Another significant difference between the two systems is that the addition of alcohol to 1A giving an alkoxo complex is endergonic by 8.1 kcal/mol, whereas the addition to 2A is exergonic by 8.9 kcal/mol. The thermodynamic difference could be the main reason for PNP-Ir system requiring lower catalyst loading than the PNN-Ru system. We discuss how the differences are resulted in terms of electronic and geometric structures of the catalysts and how to use the features in catalyst development. © 2014 American Chemical Society.

Data acquisition system for a proton imaging apparatus

CERN Document Server

Sipala, V; Bruzzi, M; Bucciolini, M; Candiano, G; Capineri, L; Cirrone, G A P; Civinini, C; Cuttone, G; Lo Presti, D; Marrazzo, L; Mazzaglia, E; Menichelli, D; Randazzo, N; Talamonti, C; Tesi, M; Valentini, S

2009-01-01

New developments in the proton-therapy field for cancer treatments, leaded Italian physics researchers to realize a proton imaging apparatus consisting of a silicon microstrip tracker to reconstruct the proton trajectories and a calorimeter to measure their residual energy. For clinical requirements, the detectors used and the data acquisition system should be able to sustain about 1 MHz proton rate. The tracker read-out, using an ASICs developed by the collaboration, acquires the signals detector and sends data in parallel to an FPGA. The YAG:Ce calorimeter generates also the global trigger. The data acquisition system and the results obtained in the calibration phase are presented and discussed.

Properties and applications of perovskite proton conductors

Directory of Open Access Journals (Sweden)

Eduardo Caetano Camilo de Souza

2010-09-01

Full Text Available A brief overview is given of the main types and principles of solid-state proton conductors with perovskite structure. Their properties are summarized in terms of the defect chemistry, proton transport and chemical stability. A good understanding of these subjects allows the manufacturing of compounds with the desired electrical properties, for application in renewable and sustainable energy devices. A few trends and highlights of the scientific advances are given for some classes of protonic conductors. Recent results and future prospect about these compounds are also evaluated. The high proton conductivity of barium cerate and zirconate based electrolytes lately reported in the literature has taken these compounds to a highlight position among the most studied conductor ceramic materials.

History of Space Shuttle Rendezvous

Science.gov (United States)

Goodman, John L.

2011-01-01

This technical history is intended to provide a technical audience with an introduction to the rendezvous and proximity operations history of the Space Shuttle Program. It details the programmatic constraints and technical challenges encountered during shuttle development in the 1970s and over thirty years of shuttle missions. An overview of rendezvous and proximity operations on many shuttle missions is provided, as well as how some shuttle rendezvous and proximity operations systems and flight techniques evolved to meet new programmatic objectives. This revised edition provides additional information on Mercury, Gemini, Apollo, Skylab, and Apollo/Soyuz. Some chapters on the Space Shuttle have been updated and expanded. Four special focus chapters have been added to provide more detailed information on shuttle rendezvous. A chapter on the STS-39 mission of April/May 1991 describes the most complex deploy/retrieve mission flown by the shuttle. Another chapter focuses on the Hubble Space Telescope servicing missions. A third chapter gives the reader a detailed look at the February 2010 STS-130 mission to the International Space Station. The fourth chapter answers the question why rendezvous was not completely automated on the Gemini, Apollo, and Space Shuttle vehicles.

CERN Shuttles - Enlarged Regular Shuttle Services as from 8/02/2010

CERN Multimedia

2010-01-01

As of Monday 8 February 2010, please note the enhancement of the regular shuttle services: - with now two shuttles dedicated to the transportation within and between both CERN sites, Meyrin and Prevessin with bus stop at more buildings - To and from the Geneva airport every hour (from building 500) to complement the TPG bus Y For timetable details, please click here: http://gs-dep.web.cern.ch/gs-dep/groups/sem/ls/RegularShuttleTimetable_Feb2010.htm GS-SEM

Space Shuttle Rudder Speed Brake Actuator-A Case Study Probabilistic Fatigue Life and Reliability Analysis

Science.gov (United States)

Oswald, Fred B.; Savage, Michael; Zaretsky, Erwin V.

2015-01-01

The U.S. Space Shuttle fleet was originally intended to have a life of 100 flights for each vehicle, lasting over a 10-year period, with minimal scheduled maintenance or inspection. The first space shuttle flight was that of the Space Shuttle Columbia (OV-102), launched April 12, 1981. The disaster that destroyed Columbia occurred on its 28th flight, February 1, 2003, nearly 22 years after its first launch. In order to minimize risk of losing another Space Shuttle, a probabilistic life and reliability analysis was conducted for the Space Shuttle rudder/speed brake actuators to determine the number of flights the actuators could sustain. A life and reliability assessment of the actuator gears was performed in two stages: a contact stress fatigue model and a gear tooth bending fatigue model. For the contact stress analysis, the Lundberg-Palmgren bearing life theory was expanded to include gear-surface pitting for the actuator as a system. The mission spectrum of the Space Shuttle rudder/speed brake actuator was combined into equivalent effective hinge moment loads including an actuator input preload for the contact stress fatigue and tooth bending fatigue models. Gear system reliabilities are reported for both models and their combination. Reliability of the actuator bearings was analyzed separately, based on data provided by the actuator manufacturer. As a result of the analysis, the reliability of one half of a single actuator was calculated to be 98.6 percent for 12 flights. Accordingly, each actuator was subsequently limited to 12 flights before removal from service in the Space Shuttle.

Sustainable, Reliable Mission-Systems Architecture

Science.gov (United States)

O'Neil, Graham; Orr, James K.; Watson, Steve

2007-01-01

A mission-systems architecture, based on a highly modular infrastructure utilizing: open-standards hardware and software interfaces as the enabling technology is essential for affordable and sustainable space exploration programs. This mission-systems architecture requires (a) robust communication between heterogeneous system, (b) high reliability, (c) minimal mission-to-mission reconfiguration, (d) affordable development, system integration, and verification of systems, and (e) minimal sustaining engineering. This paper proposes such an architecture. Lessons learned from the Space Shuttle program and Earthbound complex engineered system are applied to define the model. Technology projections reaching out 5 years are mde to refine model details.

Shuttle Discovery Landing at Edwards

Science.gov (United States)

1989-01-01

The STS-29 Space Shuttle Discovery mission lands at NASA's then Ames-Dryden Flight Research Facility, Edwards AFB, California, early Saturday morning, 18 March 1989. Touchdown was at 6:35:49 a.m. PST and wheel stop was at 6:36:40 a.m. on runway 22. Controllers chose the concrete runway for the landing in order to make tests of braking and nosewheel steering. The STS-29 mission was very successful, completing the launch of a Tracking and Data Relay communications satellite, as well as a range of scientific experiments. Discovery's five-man crew was led by Commander Michael L. Coats, and included pilot John E. Blaha and mission specialists James P. Bagian, Robert C. Springer, and James F. Buchli. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout

Space Shuttle - A personal view

Science.gov (United States)

Mark, H.

1977-01-01

A typical flight profile for the Space Shuttle is reviewed, and the operation of the Spacelab, as well as deployment of a satellite from the Shuttle, is considered. Selection of crews for a Space Shuttle mission, which may include as many as four payload specialists, is also discussed. Since medical requirements and flight training standards need not be as high for payload specialists as for the three members of the flight crew, the Shuttle may provide an opportunity for many scientists to perform experiments in space. Investigations of the critical opalescence of fluids and laser holography are proposed for Shuttle missions; X-ray astronomy is another likely candidate for inclusion in the program.

High energy protons application for radiotherapy of the esophagus affected with cancer

International Nuclear Information System (INIS)

Ruderman, A.I.; Astrakhan, B.V.; Kulakov, G.A.; Makarova, G.V.; Zhuravleva, N.T.

1975-01-01

As in radiation therapy of tumours located elsewhere, local radiation treatment of an esophagus tumour is often aggravated by the development, after some time, of a trophic ulcer as a result of decreased regenerative ability of the irradiated sound tissues and also of newly formed hystostructures which have replaced the destroyed tumorous tissue. It has been established that the number of complications increases with the total focal dose, but at the same time (up to a certain point) the number of local curings increases as well. Some promise was shown by high-energy protons with their physical advantages unique for radiation therapy, such as the strictly controlled free path length of particles in the tissues, the presence of the Bragg peak, the absence of lateral scattering, i.e. features which permit of a high dose in the target with a minimum injury to the sound tissues surrounding the tumour. Proton therapy of esophagus cancer was carried out by two techniques, static and shuttle-rotary. The results of proton therapy of esophagus cancer indicate that the use of high-energy protons for treating esophagus cancer holds promise

Food packages for Space Shuttle

Science.gov (United States)

Fohey, M. F.; Sauer, R. L.; Westover, J. B.; Rockafeller, E. F.

1978-01-01

The paper reviews food packaging techniques used in space flight missions and describes the system developed for the Space Shuttle. Attention is directed to bite-size food cubes used in Gemini, Gemini rehydratable food packages, Apollo spoon-bowl rehydratable packages, thermostabilized flex pouch for Apollo, tear-top commercial food cans used in Skylab, polyethylene beverage containers, Skylab rehydratable food package, Space Shuttle food package configuration, duck-bill septum rehydration device, and a drinking/dispensing nozzle for Space Shuttle liquids. Constraints and testing of packaging is considered, a comparison of food package materials is presented, and typical Shuttle foods and beverages are listed.

TDRSS S-shuttle unique receiver equipment

Science.gov (United States)

Weinberg, A.; Schwartz, J. J.; Spearing, R.

1985-01-01

Beginning with STS-9, the Tracking and Date Relay Satellite system (TDRSS) will start providing S- and Ku-band communications and tracking support to the Space Shuttle and its payloads. The most significant element of this support takes place at the TDRSS White Sands Ground Terminal, which processes the Shuttle return link S- and Ku-band signals. While Ku-band hardware available to other TDRSS users is also applied to Ku-Shuttle, stringent S-Shuttle link margins have precluded the application of the standard TDRSS S-band processing equipment to S-Shuttle. It was therfore found necessary to develop a unique S-Shuttle Receiver that embodies state-of-the-art digital technology and processing techniques. This receiver, developed by Motorola, Inc., enhances link margins by 1.5 dB relative to the standard S-band equipment and its bit error rate performance is within a few tenths of a dB of theory. An overview description of the Space Shuttle Receiver Equipment (SSRE) is presented which includes the presentation of block diagrams and salient design features. Selected, measured performance results are also presented.

PREFACE: Transport phenomena in proton conducting media Transport phenomena in proton conducting media

Science.gov (United States)

Eikerling, Michael

2011-06-01

Proton transport phenomena are of paramount importance for acid-base chemistry, energy transduction in biological organisms, corrosion processes, and energy conversion in electrochemical systems such as polymer electrolyte fuel cells. The relevance for such a plethora of materials and systems, and the ever-lasting fascination with the highly concerted nature of underlying processes drive research across disciplines in chemistry, biology, physics and chemical engineering. A proton never travels alone. Proton motion is strongly correlated with its environment, usually comprised of an electrolyte and a solid or soft host material. For the transport in nature's most benign proton solvent and shuttle, water that is, insights from ab initio simulations, matured over the last 15 years, have furnished molecular details of the structural diffusion mechanism of protons. Excess proton movement in water consists of sequences of Eigen-Zundel-Eigen transitions, triggered by hydrogen bond breaking and making in the surrounding water network. Nowadays, there is little debate about the validity of this mechanism in water, which bears a stunning resemblance to the basic mechanistic picture put forward by de Grotthuss in 1806. While strong coupling of an excess proton with degrees of freedom of solvent and host materials facilitates proton motion, this coupling also creates negative synergies. In general, proton mobility in biomaterials and electrochemical proton conducting media is highly sensitive to the abundance and structure of the proton solvent. In polymer electrolyte membranes, in which protons are bound to move in nano-sized water-channels, evaporation of water or local membrane dehydration due to electro-osmotic coupling are well-known phenomena that could dramatically diminish proton conductivity. Contributions in this special issue address various vital aspects of the concerted nature of proton motion and they elucidate important structural and dynamic effects of solvent

In vivo evidence of TonB shuttling between the cytoplasmic and outer membrane in Escherichia coli.

Science.gov (United States)

Larsen, Ray A; Letain, Tracy E; Postle, Kathleen

2003-07-01

Gram-negative bacteria are able to convert potential energy inherent in the proton gradient of the cytoplasmic membrane into active nutrient transport across the outer membrane. The transduction of energy is mediated by TonB protein. Previous studies suggest a model in which TonB makes sequential and cyclic contact with proteins in each membrane, a process called shuttling. A key feature of shuttling is that the amino-terminal signal anchor must quit its association with the cytoplasmic membrane, and TonB becomes associated solely with the outer membrane. However, the initial studies did not exclude the possibility that TonB was artifactually pulled from the cytoplasmic membrane by the fractionation process. To resolve this ambiguity, we devised a method to test whether the extreme TonB amino-terminus, located in the cytoplasm, ever became accessible to the cys-specific, cytoplasmic membrane-impermeant molecule, Oregon Green(R) 488 maleimide (OGM) in vivo. A full-length TonB and a truncated TonB were modified to carry a sole cysteine at position 3. Both full-length TonB and truncated TonB (consisting of the amino-terminal two-thirds) achieved identical conformations in the cytoplasmic membrane, as determined by their abilities to cross-link to the cytoplasmic membrane protein ExbB and their abilities to respond conformationally to the presence or absence of proton motive force. Full-length TonB could be amino-terminally labelled in vivo, suggesting that it was periplasmically exposed. In contrast, truncated TonB, which did not associate with the outer membrane, was not specifically labelled in vivo. The truncated TonB also acted as a control for leakage of OGM across the cytoplasmic membrane. Further, the extent of labelling for full-length TonB correlated roughly with the proportion of TonB found at the outer membrane. These findings suggest that TonB does indeed disengage from the cytoplasmic membrane during energy transduction and shuttle to the outer membrane.

Chemical Shuttle Additives in Lithium Ion Batteries

Energy Technology Data Exchange (ETDEWEB)

Patterson, Mary

2013-03-31

The goals of this program were to discover and implement a redox shuttle that is compatible with large format lithium ion cells utilizing LiNi{sub 1/3}Mn{sub 1/3}Co{sub 1/3}O{sub 2} (NMC) cathode material and to understand the mechanism of redox shuttle action. Many redox shuttles, both commercially available and experimental, were tested and much fundamental information regarding the mechanism of redox shuttle action was discovered. In particular, studies surrounding the mechanism of the reduction of the oxidized redox shuttle at the carbon anode surface were particularly revealing. The initial redox shuttle candidate, namely 2-(pentafluorophenyl)-tetrafluoro-1,3,2-benzodioxaborole (BDB) supplied by Argonne National Laboratory (ANL, Lemont, Illinois), did not effectively protect cells containing NMC cathodes from overcharge. The ANL-RS2 redox shuttle molecule, namely 1,4-bis(2-methoxyethoxy)-2,5-di-tert-butyl-benzene, which is a derivative of the commercially successful redox shuttle 2,5-di-tert-butyl-1,4-dimethoxybenzene (DDB, 3M, St. Paul, Minnesota), is an effective redox shuttle for cells employing LiFePO{sub 4} (LFP) cathode material. The main advantage of ANL-RS2 over DDB is its larger solubility in electrolyte; however, ANL-RS2 is not as stable as DDB. This shuttle also may be effectively used to rebalance cells in strings that utilize LFP cathodes. The shuttle is compatible with both LTO and graphite anode materials although the cell with graphite degrades faster than the cell with LTO, possibly because of a reaction with the SEI layer. The degradation products of redox shuttle ANL-RS2 were positively identified. Commercially available redox shuttles Li{sub 2}B{sub 12}F{sub 12} (Air Products, Allentown, Pennsylvania and Showa Denko, Japan) and DDB were evaluated and were found to be stable and effective redox shuttles at low C-rates. The Li{sub 2}B{sub 12}F{sub 12} is suitable for lithium ion cells utilizing a high voltage cathode (potential that is higher

Self-sustained oscillations in nanoelectromechanical systems induced by Kondo resonance

International Nuclear Information System (INIS)

Song, Taegeun; Kiselev, Mikhail N; Kikoin, Konstantin; Shekhter, Robert I; Gorelik, Leonid Y

2014-01-01

We investigate the instability and dynamical properties of nanoelectromechanical systems represented by a single-electron device containing movable quantum dots attached to a vibrating cantilever via asymmetric tunnel contacts. The Kondo resonance in electron tunneling between the source and shuttle facilitates self-sustained oscillations originating from the strong coupling of mechanical and electronic/spin degrees of freedom. We analyze a stability diagram for the two-channel Kondo shuttling regime due to limitations given by the electromotive force acting on a moving shuttle, and find that the saturation oscillation amplitude is associated with the retardation effect of the Kondo cloud. The results shed light on possible ways to experimentally realize the Kondo-cloud dynamical probe by using high mechanical dissipation tunability as well as supersensitive detection of mechanical displacement

Self-sustained oscillations in nanoelectromechanical systems induced by Kondo resonance

Science.gov (United States)

Song, Taegeun; Kiselev, Mikhail N.; Kikoin, Konstantin; Shekhter, Robert I.; Gorelik, Leonid Y.

2014-03-01

We investigate the instability and dynamical properties of nanoelectromechanical systems represented by a single-electron device containing movable quantum dots attached to a vibrating cantilever via asymmetric tunnel contacts. The Kondo resonance in electron tunneling between the source and shuttle facilitates self-sustained oscillations originating from the strong coupling of mechanical and electronic/spin degrees of freedom. We analyze a stability diagram for the two-channel Kondo shuttling regime due to limitations given by the electromotive force acting on a moving shuttle, and find that the saturation oscillation amplitude is associated with the retardation effect of the Kondo cloud. The results shed light on possible ways to experimentally realize the Kondo-cloud dynamical probe by using high mechanical dissipation tunability as well as supersensitive detection of mechanical displacement.

CERN Shuttles - NEW Regular Shuttle Services as from 11/01/2010

CERN Document Server

GS Department

2010-01-01

As of Monday 11 January a new regular shuttle service (from Monday to Friday) will be available to facilitate transportation: Within and between both CERN sites, Meyrin and Prevessin; To and from the following LHC points: ATLAS, ALICE, CMS, LHCb. For further details, please consult the timetable for this service. We should also like to take this opportunity to encourage you to use the new regular TPG Y bus service rather than the special on-demand CERN transport service to and from Geneva Airport whenever possible. The TPG buses run from 06:00 to 00:30. For further details, please consult the TPG timetable. Please do not hesitate to give us your feedback on the shuttle services: e-mail to veronique.marchal@cern.ch. In case of problems with the shuttles, please contact 75411. GS-SEM Group Infrastructure and General Services Department

Proton-air and proton-proton cross sections

Directory of Open Access Journals (Sweden)

Ulrich Ralf

2013-06-01

Full Text Available Different attempts to measure hadronic cross sections with cosmic ray data are reviewed. The major results are compared to each other and the differences in the corresponding analyses are discussed. Besides some important differences, it is crucial to see that all analyses are based on the same fundamental relation of longitudinal air shower development to the observed fluctuation of experimental observables. Furthermore, the relation of the measured proton-air to the more fundamental proton-proton cross section is discussed. The current global picture combines hadronic proton-proton cross section data from accelerator and cosmic ray measurements and indicates a good consistency with predictions of models up to the highest energies.

Distinguishing Two Ammonium and Triazolium Sites of Interaction in a Three-Station [2]Rotaxane Molecular Shuttle.

Science.gov (United States)

Waelès, Philip; Fournel-Marotte, Karine; Coutrot, Frédéric

2017-08-25

This paper reports on the synthesis of a tri-stable [2]rotaxane molecular shuttle, in which the motion of the macrocycle is triggered by either selective protonation/deprotonation or specific carbamoylation/decarbamoylation of an alkylbenzylamine. The threaded axle is surrounded by a dibenzo[24]crown[8] (DB24C8) macrocycle and contains three sites of different binding affinities towards the macrocycle. An N-methyltriazolium moiety acts as a molecular station that has weak affinity for the DB24C8 macrocycle and is located in the centre of the molecular axle. Two other molecular stations, arylammonium and alkylbenzylammonium moieties, sit on either side of the triazolium moiety along the molecular axle and have stronger affinities for the DB24C8 macrocycle. These two ammonium moieties are covalently linked to two different stopper groups at each extremity of the thread: a tert-butylphenyl group and a substituted DB24C8 unit. Owing to steric hindrance, the former does not allow any π-π stacking interactions with the encircling DB24C8 macrocycle, whereas the latter residue does; therefore, this allows the discrimination of the two ammonium stations by the surrounding DB24C8 macrocycle in the fully protonated state. In the deprotonated state, the contrasting reactivity of the amine functional groups, as either a base or a nucleophile, allows for selective reactions that trigger the controlled shuttling of the macrocycle around the three molecular stations. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

NASA Contingency Shuttle Crew Support (CSCS) Medical Operations

Science.gov (United States)

Adams, Adrien

2010-01-01

The genesis of the space shuttle began in the 1930's when Eugene Sanger came up with the idea of a recyclable rocket plane that could carry a crew of people. The very first Shuttle to enter space was the Shuttle "Columbia" which launched on April 12 of 1981. Not only was "Columbia" the first Shuttle to be launched, but was also the first to utilize solid fuel rockets for U.S. manned flight. The primary objectives given to "Columbia" were to check out the overall Shuttle system, accomplish a safe ascent into orbit, and to return back to earth for a safe landing. Subsequent to its first flight Columbia flew 27 more missions but on February 1st, 2003 after a highly successful 16 day mission, the Columbia, STS-107 mission, ended in tragedy. With all Shuttle flight successes come failures such as the fatal in-flight accident of STS 107. As a result of the STS 107 accident, and other close-calls, the NASA Space Shuttle Program developed contingency procedures for a rescue mission by another Shuttle if an on-orbit repair was not possible. A rescue mission would be considered for a situation where a Shuttle and the crew were not in immediate danger, but, was unable to return to Earth or land safely. For Shuttle missions to the International Space Station (ISS), plans were developed so the Shuttle crew would remain on board ISS for an extended period of time until rescued by a "rescue" Shuttle. The damaged Shuttle would subsequently be de-orbited unmanned. During the period when the ISS Crew and Shuttle crew are on board simultaneously multiple issues would need to be worked including, but not limited to: crew diet, exercise, psychological support, workload, and ground contingency support

Metal-free aqueous redox capacitor via proton rocking-chair system in an organic-based couple

Science.gov (United States)

Tomai, Takaaki; Mitani, Satoshi; Komatsu, Daiki; Kawaguchi, Yuji; Honma, Itaru

2014-01-01

Safe and inexpensive energy storage devices with long cycle lifetimes and high power and energy densities are mandatory for the development of electrical power grids that connect with renewable energy sources. In this study, we demonstrated metal-free aqueous redox capacitors using couples comprising low-molecular-weight organic compounds. In addition to the electric double layer formation, proton insertion/extraction reactions between a couple consisting of inexpensive quinones/hydroquinones contributed to the energy storage. This energy storage mechanism, in which protons are shuttled back and forth between two electrodes upon charge and discharge, can be regarded as a proton rocking-chair system. The fabricated capacitor showed a large capacity (>20 Wh/kg), even in the applied potential range between 0–1 V, and high power capability (>5 A/g). The support of the organic compounds in nanoporous carbon facilitated the efficient use of the organic compounds with a lifetime of thousands of cycles. PMID:24395117

Proton-proton bremsstrahlung

International Nuclear Information System (INIS)

Fearing, H.W.

1990-01-01

We summarize some of the information about the nucleon-nucleon force which has been obtained by comparing recent calculations of proton-proton bremsstrahlung with cross section and analyzing power data from the new TRIUMF bremsstrahlung experiment. Some comments are made as to how these results can be extended to neutron-proton bremsstrahlung. (Author) 17 refs., 6 figs

Teledyne Energy Systems, Inc., Proton Exchange Member (PEM) Fuel Cell Engineering Model Powerplant. Test Report: Initial Benchmark Tests in the Original Orientation

Science.gov (United States)

Loyselle, Patricia; Prokopius, Kevin

2011-01-01

Proton Exchange Membrane (PEM) fuel cell technology is the leading candidate to replace the alkaline fuel cell technology, currently used on the Shuttle, for future space missions. During a 5-yr development program, a PEM fuel cell powerplant was developed. This report details the initial performance evaluation test results of the powerplant.

Protein proton-proton dynamics from amide proton spin flip rates

International Nuclear Information System (INIS)

Weaver, Daniel S.; Zuiderweg, Erik R. P.

2009-01-01

Residue-specific amide proton spin-flip rates K were measured for peptide-free and peptide-bound calmodulin. K approximates the sum of NOE build-up rates between the amide proton and all other protons. This work outlines the theory of multi-proton relaxation, cross relaxation and cross correlation, and how to approximate it with a simple model based on a variable number of equidistant protons. This model is used to extract the sums of K-rates from the experimental data. Error in K is estimated using bootstrap methodology. We define a parameter Q as the ratio of experimental K-rates to theoretical K-rates, where the theoretical K-rates are computed from atomic coordinates. Q is 1 in the case of no local motion, but decreases to values as low as 0.5 with increasing domination of sidechain protons of the same residue to the amide proton flips. This establishes Q as a monotonous measure of local dynamics of the proton network surrounding the amide protons. The method is applied to the study of proton dynamics in Ca 2+ -saturated calmodulin, both free in solution and bound to smMLCK peptide. The mean Q is 0.81 ± 0.02 for free calmodulin and 0.88 ± 0.02 for peptide-bound calmodulin. This novel methodology thus reveals the presence of significant interproton disorder in this protein, while the increase in Q indicates rigidification of the proton network upon peptide binding, confirming the known high entropic cost of this process

Quantum Shuttle in Phase Space

DEFF Research Database (Denmark)

Novotny, Tomas; Donarini, Andrea; Jauho, Antti-Pekka

2003-01-01

Abstract: We present a quantum theory of the shuttle instability in electronic transport through a nanostructure with a mechanical degree of freedom. A phase space formulation in terms of the Wigner function allows us to identify a crossover from the tunneling to the shuttling regime, thus...

Upgrading the Space Shuttle.

Science.gov (United States)

1999-01-01

Motors, Honda , Toyota , and Nissan ). By learning from and applying the technologies developed elsewhere, NASA could greatly leverage its funding for...assessing risks to the shuttle. The committee believes that this tool has the potential to be very helpful in assessing and comparing the impact of...environmental regulations). Figure 2-2 shows how the S&PU budget compared to the total shuttle budget during four different years since 1985

Dextromethorphan inhibition of voltage-gated proton currents in BV2 microglial cells.

Science.gov (United States)

Song, Jin-Ho; Yeh, Jay Z

2012-05-10

Dextromethorphan, an antitussive drug, has a neuroprotective property as evidenced by its inhibition of microglial production of pro-inflammatory cytokines and reactive oxygen species. The microglial activation requires NADPH oxidase activity, which is sustained by voltage-gated proton channels in microglia as they dissipate an intracellular acid buildup. In the present study, we examined the effect of dextromethorphan on proton currents in microglial BV2 cells. Dextromethorphan reversibly inhibited proton currents with an IC(50) value of 51.7 μM at an intracellular/extracellular pH gradient of 5.5/7.3. Dextromethorphan did not change the reversal potential or the voltage dependence of the gating. Dextrorphan and 3-hydroxymorphinan, major metabolites of dextromethorphan, and dextromethorphan methiodide were ineffective in inhibiting proton currents. The results indicate that dextromethorphan inhibition of proton currents would suppress NADPH oxidase activity and, eventually, microglial activation. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Space Shuttle critical function audit

Science.gov (United States)

Sacks, Ivan J.; Dipol, John; Su, Paul

1990-01-01

A large fault-tolerance model of the main propulsion system of the US space shuttle has been developed. This model is being used to identify single components and pairs of components that will cause loss of shuttle critical functions. In addition, this model is the basis for risk quantification of the shuttle. The process used to develop and analyze the model is digraph matrix analysis (DMA). The DMA modeling and analysis process is accessed via a graphics-based computer user interface. This interface provides coupled display of the integrated system schematics, the digraph models, the component database, and the results of the fault tolerance and risk analyses.

Brand-new signage for the CERN shuttles

CERN Multimedia

Roberto Cantoni

2010-01-01

If, after reading the title of this article, you're striving to remember what the signs for the CERN shuttles look like, then you just hit the nail on the head: we bet that only a few people can actually do so. In order to make it easier for CERN users to move around the CERN sites, a graphic restyling of the shuttle signage has been implemented. You will start to see the new timetables in the coming days.   Larisa Kuchina, a graphic designer in the Communication Group, restyled the shuttle signage to make it more visible and intelligible. “I was inspired by the very clear and user friendly interface of the Geneva Public Transport system (TPG)”, explains Larisa. “Each timetable will also include the corresponding shuttle route. We will soon introduce new road signs for shuttle stops to make sure they are visible from a distance”. There are currently four shuttle lines, serving 28,000 passengers since February 2010: two of them operate between Meyrin and Pr...

Space Shuttle Endeavour launch

Science.gov (United States)

1992-01-01

A smooth countdown culminated in a picture-perfect launch as the Space Shuttle Endeavour (STS-47) climbed skyward atop a ladder of billowing smoke. Primary payload for the plarned seven-day flight was Spacelab-J science laboratory. The second flight of Endeavour marks a number of historic firsts: the first space flight of an African-American woman, the first Japanese citizen to fly on a Space Shuttle, and the first married couple to fly in space.

Space Shuttle Main Engine Public Test Firing

Science.gov (United States)

2000-01-01

A new NASA Space Shuttle Main Engine (SSME) roars to the approval of more than 2,000 people who came to John C. Stennis Space Center in Hancock County, Miss., on July 25 for a flight-certification test of the SSME Block II configuration. The engine, a new and significantly upgraded shuttle engine, was delivered to NASA's Kennedy Space Center in Florida for use on future shuttle missions. Spectators were able to experience the 'shake, rattle and roar' of the engine, which ran for 520 seconds - the length of time it takes a shuttle to reach orbit.

Current Noise Spectrum of a Quantum Shuttle

DEFF Research Database (Denmark)

Flindt, Christian; Novotny, T.; Jauho, Antti-Pekka

2005-01-01

We present a method for calculating the full current noise spectrum S(omega) for the class of nano-electromechanical systems (NEMS) that can be described by a Markovian generalized master equation. As a specific example we apply the method to a quantum shuttle. The noise spectrum of the shuttle has...... peaks at integer multiples of the mechanical frequency, which is slightly renormalized. The renormalization explains a previously observed small deviation of the shuttle Current compared to the expected value given by the product of the natural mechanical frequency and the electron charge. For a certain...... parameter range the quantum shuttle exhibits a coexistence regime, where the charges are transported by two different mechanisms: Shuttling and sequential tunneling. In our previous studies we showed that characteristic features in the zero-frequency noise could be quantitatively understood as a slow...

Nanoparticle shuttle memory

Science.gov (United States)

Zettl, Alex Karlwalter [Kensington, CA

2012-03-06

A device for storing data using nanoparticle shuttle memory having a nanotube. The nanotube has a first end and a second end. A first electrode is electrically connected to the first end of the nanotube. A second electrode is electrically connected to the second end of the nanotube. The nanotube has an enclosed nanoparticle shuttle. A switched voltage source is electrically connected to the first electrode and the second electrode, whereby a voltage may be controllably applied across the nanotube. A resistance meter is also connected to the first electrode and the second electrode, whereby the electrical resistance across the nanotube can be determined.

Intelligent Shuttle Management and Routing Algorithm

Science.gov (United States)

Thomas, Toshen M.; Subashanthini, S.

2017-11-01

Nowadays, most of the big Universities and campuses have Shuttle cabs running in them to cater the transportational needs of the students and faculties. While some shuttle services ask for a meagre sum to be paid for the usage, no digital payment system is onboard these vehicles to go truly cashless. Even more troublesome is the fact that sometimes during the day, some of these cabs run with bare number of passengers, which can result in unwanted budget loss to the shuttle operator. The main purpose of this paper is to create a system with two types of applications: A web portal and an Android app, to digitize the Shuttle cab industry. This system can be used for digital cashless payment feature, tracking passengers, tracking cabs and more importantly, manage the number of shuttle cabs in every route to maximize profit. This project is built upon an ASP.NET website connected to a cloud service along with an Android app that tracks and reads the passengers ID using an attached barcode reader along with the current GPS coordinates, and sends these data to the cloud for processing using the phone’s internet connectivity.

Shuttle on-orbit contamination and environmental effects

Science.gov (United States)

Leger, L. J.; Jacobs, S.; Ehlers, H. K. F.; Miller, E.

1985-01-01

Ensuring the compatibility of the space shuttle system with payloads and payload measurements is discussed. An extensive set of quantitative requirements and goals was developed and implemented by the space shuttle program management. The performance of the Shuttle system as measured by these requirements and goals was assessed partly through the use of the induced environment contamination monitor on Shuttle flights 2, 3, and 4. Contamination levels are low and generally within the requirements and goals established. Additional data from near-term payloads and already planned contamination measurements will complete the environment definition and allow for the development of contamination avoidance procedures as necessary for any payload.

Use of PRA in Shuttle Decision Making Process

Science.gov (United States)

Boyer, Roger L.; Hamlin, Teri L.

2010-01-01

How do you use PRA to support an operating program? This presentation will explore how the Shuttle Program Management has used the Shuttle PRA in its decision making process. It will reveal how the PRA has evolved from a tool used to evaluate Shuttle upgrades like Electric Auxiliary Power Unit (EAPU) to a tool that supports Flight Readiness Reviews (FRR) and real-time flight decisions. Specific examples of Shuttle Program decisions that have used the Shuttle PRA as input will be provided including how it was used in the Hubble Space Telescope (HST) manifest decision. It will discuss the importance of providing management with a clear presentation of the analysis, applicable assumptions and limitations, along with estimates of the uncertainty. This presentation will show how the use of PRA by the Shuttle Program has evolved overtime and how it has been used in the decision making process providing specific examples.

Neutrons and sustainable energy research

International Nuclear Information System (INIS)

Peterson, V.

2009-01-01

Full text: Neutron scattering is essential for the study of sustainable energy materials, including the areas of hydrogen research (such as its separation, storage, and use in fuel-cells) and energy transport (such as fuel-cell and battery materials). Researchers at the Bragg Institute address critical questions in sustainable energy research, with researchers providing a source of expertise for external collaborators, specialist analysis equipment, and acting as a point of contact for the study of sustainable energy materials using neutron scattering. Some recent examples of sustainable energy materials research using neutron scattering will be presented. These examples include the storage of energy, in the form of hydrogen through a study of its location in and interaction with new porous hydrogen storage materials [1-3] and in battery materials through in-situ studies of structure during charge-discharge cycling, and use of energy in fuel cells by studying proton diffusion through fuel cell membranes.

Steady equilibrium of a cylindrically symmetric plasma sustained by fueling

International Nuclear Information System (INIS)

Tomita, Yukihiro; Momota, Hiromu

1993-01-01

By introducing a novel and natural method to obtain a steady equilibrium, it is shown that a pressure gradient produced by the particle injection or resultant diamagnetic current can sustain only an equilibrium of a diffused linear pinch. For an extremely elongated FRC where magnetic field vanishes at a certain point, a seed current is needed to sustain configuration in a steady state equilibrium. A directed flow of fusion produced protons forms a seed current and consequently it sustains a steady FRC equilibrium by fueling only once D- 3 He burning takes place. Effects of anomalous transports on the sustainment are discussed. (author)

Shuttle Columbia Post-landing Tow - with Reflection in Water

Science.gov (United States)

1982-01-01

A rare rain allowed this reflection of the Space Shuttle Columbia as it was towed 16 Nov. 1982, to the Shuttle Processing Area at NASA's Ames-Dryden Flight Research Facility (from 1976 to 1981 and after 1994, the Dryden Flight Research Center), Edwards, California, following its fifth flight in space. Columbia was launched on mission STS-5 11 Nov. 1982, and landed at Edwards Air Force Base on concrete runway 22. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines withtwo solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the mission. They are then removed after the Space Shuttle returns to Earth and can be reused on future flights. Some of these orbital laboratories, like the Spacelab, provide facilities for several specialists to conduct experiments in such fields as medicine, astronomy, and materials

Proton radiography to improve proton therapy treatment

NARCIS (Netherlands)

Takatsu, J.; van der Graaf, E. R.; van Goethem, Marc-Jan; van Beuzekom, M.; Klaver, T.; Visser, Jan; Brandenburg, S.; Biegun, A. K.

The quality of cancer treatment with protons critically depends on an accurate prediction of the proton stopping powers for the tissues traversed by the protons. Today, treatment planning in proton radiotherapy is based on stopping power calculations from densities of X-ray Computed Tomography (CT)

Proton radioactivity from proton-rich nuclei

International Nuclear Information System (INIS)

Guzman, F.; Goncalves, M.; Tavares, O.A.P.; Duarte, S.B.; Garcia, F.; Rodriguez, O.

1999-03-01

Half-lives for proton emission from proton-rich nuclei have been calculated by using the effective liquid drop model of heavy-particle decay of nuclei. It is shown that this model is able to offer results or spontaneous proton-emission half-life-values in excellent agreement with the existing experimental data. Predictions of half-life-values for other possible proton-emission cases are present for null orbital angular momentum. (author)

Redox shuttles for safer lithium-ion batteries

International Nuclear Information System (INIS)

Chen, Zonghai; Qin, Yan; Amine, Khalil

2009-01-01

Overcharge protection is not only critical for preventing the thermal runaway of lithium-ion batteries during operation, but also important for automatic capacity balancing during battery manufacturing and repair. A redox shuttle is an electrolyte additive that can be used as intrinsic overcharge protection mechanism to enhance the safety characteristics of lithium-ion batteries. The advances on stable redox shuttles are briefly reviewed. Fundamental studies for designing stable redox shuttles are also discussed.

Enhanced Proton Conductivity in Y-Doped BaZrO3 via Strain Engineering.

Science.gov (United States)

Fluri, Aline; Marcolongo, Aris; Roddatis, Vladimir; Wokaun, Alexander; Pergolesi, Daniele; Marzari, Nicola; Lippert, Thomas

2017-12-01

The effects of stress-induced lattice distortions (strain) on the conductivity of Y-doped BaZrO 3 , a high-temperature proton conductor with key technological applications for sustainable electrochemical energy conversion, are studied. Highly ordered epitaxial thin films are grown in different strain states while monitoring the stress generation and evolution in situ. Enhanced proton conductivity due to lower activation energies is discovered under controlled conditions of tensile strain. In particular, a twofold increased conductivity is measured at 200 °C along a 0.7% tensile strained lattice. This is at variance with conclusions coming from force-field simulations or the static calculations of diffusion barriers. Here, extensive first-principles molecular dynamic simulations of proton diffusivity in the proton-trapping regime are therefore performed and found to agree with the experiments. The simulations highlight that compressive strain confines protons in planes parallel to the substrate, while tensile strain boosts diffusivity in the perpendicular direction, with the net result that the overall conductivity is enhanced. It is indeed the presence of the dopant and the proton-trapping effect that makes tensile strain favorable for proton conduction.

Shuttle Ku-band bent-pipe implementation considerations. [for Space Shuttle digital communication systems

Science.gov (United States)

Batson, B. H.; Seyl, J. W.; Huth, G. K.

1977-01-01

This paper describes an approach for relay of data-modulated subcarriers from Shuttle payloads through the Shuttle Ku-band communications subsystem (and subsequently through a tracking and data relay satellite system to a ground terminal). The novelty is that a channel originally provided for baseband digital data is shown to be suitable for this purpose; the resulting transmission scheme is referred to as a narrowband bent-pipe scheme. Test results demonstrating the validity of the narrowband bent-pipe mode are presented, and limitations on system performance are described.

Proton Radiography to Improve Proton Radiotherapy : Simulation Study at Different Proton Beam Energies

NARCIS (Netherlands)

Biegun, Aleksandra; Takatsu, Jun; van Goethem, Marc-Jan; van der Graaf, Emiel; van Beuzekom, Martin; Visser, Jan; Brandenburg, Sijtze

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have systematic uncertainties in the calculated proton range in a

Shot noise of a quantum shuttle

DEFF Research Database (Denmark)

Novotny, Tomas; Donarini, Andrea; Flindt, Christian

2004-01-01

We formulate a theory for shot noise in quantum nanoelectromechanical systems. As a specific example, the theory is applied to a quantum shuttle, and the zero-frequency noise, measured by the Fano factor F, is computed. F reaches very low values (Fsimilar or equal to10(-2)) in the shuttling regim...

Proton solvation and proton transfer in chemical and electrochemical processes

International Nuclear Information System (INIS)

Lengyel, S.; Conway, B.E.

1983-01-01

This chapter examines the proton solvation and characterization of the H 3 O + ion, proton transfer in chemical ionization processes in solution, continuous proton transfer in conductance processes, and proton transfer in electrode processes. Topics considered include the condition of the proton in solution, the molecular structure of the H 3 O + ion, thermodynamics of proton solvation, overall hydration energy of the proton, hydration of H 3 O + , deuteron solvation, partial molal entropy and volume and the entropy of proton hydration, proton solvation in alcoholic solutions, analogies to electrons in semiconductors, continuous proton transfer in conductance, definition and phenomenology of the unusual mobility of the proton in solution, solvent structure changes in relation to anomalous proton mobility, the kinetics of the proton-transfer event, theories of abnormal proton conductance, and the general theory of the contribution of transfer reactions to overall transport processes

Protons and how they are transported by proton pumps

DEFF Research Database (Denmark)

Buch-Pedersen, Morten Jeppe; Pedersen, Bjørn Panyella; Nissen, Poul

2008-01-01

molecular components that allow the plasma membrane proton H(+)-ATPase to carry out proton transport against large membrane potentials. When divergent proton pumps such as the plasma membrane H(+)-ATPase, bacteriorhodopsin, and F(O)F(1) ATP synthase are compared, unifying mechanistic premises for biological...... proton pumps emerge. Most notably, the minimal pumping apparatus of all pumps consists of a central proton acceptor/donor, a positively charged residue to control pK (a) changes of the proton acceptor/donor, and bound water molecules to facilitate rapid proton transport along proton wires....

CERN Shuttles – TRAM arrival – Two additional shuttles as from 2 May 2011

CERN Document Server

General Infrastructure Services Department

2011-01-01

With the TRAM’s arrival at CERN and to facilitate mobility inside CERN, the GS Department is reinforcing CERN's shuttle services and will provide users with two additional shuttles from/to Building 33 (CERN Reception) as from Monday 2 May: Circuit No. 5: serving the Meyrin site (approx. every 15 minutes) •\tfrom 7·30 to 9·15 •\tfrom 11·30 to 13·28 (serving restaurants Nos.1 and 2) •\tfrom 16·30 to 18·35   Circuit No. 6: serving the Prevessin site (approx. every 20 minutes) •\tfrom 7·30 to 9·10 •\tfrom 11·30 to 13·28 (serving restaurants Nos. 1, 2 and 3) •\tfrom 16·30 to 18·23 For further details, please consult the timetable for these circuits at the following url: http://gs-dep.web.cern.ch/gs-dep/groups/SEM/ls/ShuttleService/ Please do not hesitate to give us your feedback...

STS-62 Space Shuttle mission report

Science.gov (United States)

Fricke, Robert W., Jr.

1994-01-01

The STS-62 Space Shuttle Program Mission Report summarizes the Payload activities as well as the Orbiter, External Tank (ET), Solid Rocket Booster (SRB), Redesigned Solid Rocket Motor (RSRM), and the Space Shuttle main engine (SSHE) systems performance during the sixty-first flight of the Space Shuttle Program and sixteenth flight of the Orbiter vehicle Columbia (OV-102). In addition to the Orbiter, the flight vehicle consisted of an ET designated as ET-62; three SSME's which were designated as serial numbers 2031, 2109, and 2029 in positions 1, 2, and 3, respectively; and two SRB's which were designated BI-064. The RSRM's that were installed in each SRB were designated as 360L036A (lightweight) for the left SRB, and 36OWO36B (welterweight) for the right SRB. This STS-62 Space Shuttle Program Mission Report fulfills the Space Shuttle Program requirement as documented in NSTS 07700, Volume 8, Appendix E. That document requires that each major organizational element supporting the Program report the results of its hardware evaluation and mission performance plus identify all related in-flight anomalies. The primary objectives of the STS-62 mission were to perform the operations of the United States Microgravity Payload-2 (USMP-2) and the Office of Aeronautics and Space Technology-2 (OAST-2) payload. The secondary objectives of this flight were to perform the operations of the Dexterous End Effector (DEE), the Shuttle Solar Backscatter Ultraviolet/A (SSBUV/A), the Limited Duration Space Environment Candidate Material Exposure (LDCE), the Advanced Protein Crystal Growth (APCG), the Physiological Systems Experiments (PSE), the Commercial Protein Crystal Growth (CPCG), the Commercial Generic Bioprocessing Apparatus (CGBA), the Middeck Zero-Gravity Dynamics Experiment (MODE), the Bioreactor Demonstration System (BDS), the Air Force Maui Optical Site Calibration Test (AMOS), and the Auroral Photography Experiment (APE-B).

Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

Energy Technology Data Exchange (ETDEWEB)

Henry, Rowan M; Caplan, David; Pomes, Regis [Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, M5G 1X8 (Canada); Fadda, Elisa, E-mail: pomes@sickkids.ca [Department of Chemistry, University of Galway (Ireland)

2011-06-15

Cytochrome c oxidase, the terminal enzyme of the respiratory chain, utilizes the reduction of dioxygen into water to pump protons across the mitochondrial inner membrane. The principal pathway of proton uptake into the enzyme, the D channel, is a 2.5 nm long channel-like cavity named after a conserved, negatively charged aspartic acid (D) residue thought to help recruiting protons to its entrance (D132 in the first subunit of the S. sphaeroides enzyme). The single-point mutation of D132 to asparagine (N), a neutral residue, abolishes enzyme activity. Conversely, replacing conserved N139, one-third into the D channel, by D, induces a decoupled phenotype, whereby oxygen reduction proceeds but not proton pumping. Intriguingly, the double mutant D132N/N139D, which conserves the charge of the D channel, restores the wild-type phenotype. We use molecular dynamics simulations and electrostatic calculations to examine the structural and physical basis for the coupling of proton pumping and oxygen chemistry in single and double N139D mutants. The potential of mean force for the conformational isomerization of N139 and N139D side chains reveals the presence of three rotamers, one of which faces the channel entrance. This out-facing conformer is metastable in the wild-type and in the N139D single mutant, but predominant in the double mutant thanks to the loss of electrostatic repulsion with the carboxylate group of D132. The effects of mutations and conformational isomerization on the pKa of E286, an essential proton-shuttling residue located at the top of the D channel, are shown to be consistent with the electrostatic control of proton pumping proposed recently (Fadda et al 2008 Biochim. Biophys. Acta 1777 277-84). Taken together, these results suggest that preserving the spatial distribution of charges at the entrance of the D channel is necessary to guarantee both the uptake and the relay of protons to the active site of the enzyme. These findings highlight the interplay

Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

International Nuclear Information System (INIS)

Henry, Rowan M; Caplan, David; Pomes, Regis; Fadda, Elisa

2011-01-01

Cytochrome c oxidase, the terminal enzyme of the respiratory chain, utilizes the reduction of dioxygen into water to pump protons across the mitochondrial inner membrane. The principal pathway of proton uptake into the enzyme, the D channel, is a 2.5 nm long channel-like cavity named after a conserved, negatively charged aspartic acid (D) residue thought to help recruiting protons to its entrance (D132 in the first subunit of the S. sphaeroides enzyme). The single-point mutation of D132 to asparagine (N), a neutral residue, abolishes enzyme activity. Conversely, replacing conserved N139, one-third into the D channel, by D, induces a decoupled phenotype, whereby oxygen reduction proceeds but not proton pumping. Intriguingly, the double mutant D132N/N139D, which conserves the charge of the D channel, restores the wild-type phenotype. We use molecular dynamics simulations and electrostatic calculations to examine the structural and physical basis for the coupling of proton pumping and oxygen chemistry in single and double N139D mutants. The potential of mean force for the conformational isomerization of N139 and N139D side chains reveals the presence of three rotamers, one of which faces the channel entrance. This out-facing conformer is metastable in the wild-type and in the N139D single mutant, but predominant in the double mutant thanks to the loss of electrostatic repulsion with the carboxylate group of D132. The effects of mutations and conformational isomerization on the pKa of E286, an essential proton-shuttling residue located at the top of the D channel, are shown to be consistent with the electrostatic control of proton pumping proposed recently (Fadda et al 2008 Biochim. Biophys. Acta 1777 277-84). Taken together, these results suggest that preserving the spatial distribution of charges at the entrance of the D channel is necessary to guarantee both the uptake and the relay of protons to the active site of the enzyme. These findings highlight the interplay

Molecular basis of proton uptake in single and double mutants of cytochrome c oxidase

Science.gov (United States)

Henry, Rowan M.; Caplan, David; Fadda, Elisa; Pomès, Régis

2011-06-01

Cytochrome c oxidase, the terminal enzyme of the respiratory chain, utilizes the reduction of dioxygen into water to pump protons across the mitochondrial inner membrane. The principal pathway of proton uptake into the enzyme, the D channel, is a 2.5 nm long channel-like cavity named after a conserved, negatively charged aspartic acid (D) residue thought to help recruiting protons to its entrance (D132 in the first subunit of the S. sphaeroides enzyme). The single-point mutation of D132 to asparagine (N), a neutral residue, abolishes enzyme activity. Conversely, replacing conserved N139, one-third into the D channel, by D, induces a decoupled phenotype, whereby oxygen reduction proceeds but not proton pumping. Intriguingly, the double mutant D132N/N139D, which conserves the charge of the D channel, restores the wild-type phenotype. We use molecular dynamics simulations and electrostatic calculations to examine the structural and physical basis for the coupling of proton pumping and oxygen chemistry in single and double N139D mutants. The potential of mean force for the conformational isomerization of N139 and N139D side chains reveals the presence of three rotamers, one of which faces the channel entrance. This out-facing conformer is metastable in the wild-type and in the N139D single mutant, but predominant in the double mutant thanks to the loss of electrostatic repulsion with the carboxylate group of D132. The effects of mutations and conformational isomerization on the pKa of E286, an essential proton-shuttling residue located at the top of the D channel, are shown to be consistent with the electrostatic control of proton pumping proposed recently (Fadda et al 2008 Biochim. Biophys. Acta 1777 277-84). Taken together, these results suggest that preserving the spatial distribution of charges at the entrance of the D channel is necessary to guarantee both the uptake and the relay of protons to the active site of the enzyme. These findings highlight the interplay

Space Shuttle Underside Astronaut Communications Performance Evaluation

Science.gov (United States)

Hwu, Shian U.; Dobbins, Justin A.; Loh, Yin-Chung; Kroll, Quin D.; Sham, Catherine C.

2005-01-01

The Space Shuttle Ultra High Frequency (UHF) communications system is planned to provide Radio Frequency (RF) coverage for astronauts working underside of the Space Shuttle Orbiter (SSO) for thermal tile inspection and repairing. This study is to assess the Space Shuttle UHF communication performance for astronauts in the shadow region without line-of-sight (LOS) to the Space Shuttle and Space Station UHF antennas. To insure the RF coverage performance at anticipated astronaut worksites, the link margin between the UHF antennas and Extravehicular Activity (EVA) Astronauts with significant vehicle structure blockage was analyzed. A series of near-field measurements were performed using the NASA/JSC Anechoic Chamber Antenna test facilities. Computational investigations were also performed using the electromagnetic modeling techniques. The computer simulation tool based on the Geometrical Theory of Diffraction (GTD) was used to compute the signal strengths. The signal strength was obtained by computing the reflected and diffracted fields along the propagation paths between the transmitting and receiving antennas. Based on the results obtained in this study, RF coverage for UHF communication links was determined for the anticipated astronaut worksite in the shadow region underneath the Space Shuttle.

Shuttle requests

CERN Multimedia

2007-01-01

Please note that starting from 1 March 2007, the shuttle requests: for official visits or bidders' conferences on the CERN site; towards/from the airport or central Geneva; for long distances, shall be made via Fm.Support@cern.ch or by calling 77777. The radio taxi will still be reachable at 76969. TS/FM Group

Probabilistic Analysis of Space Shuttle Body Flap Actuator Ball Bearings

Science.gov (United States)

Oswald, Fred B.; Jett, Timothy R.; Predmore, Roamer E.; Zaretsky, Erwin V.

2008-01-01

A probabilistic analysis, using the 2-parameter Weibull-Johnson method, was performed on experimental life test data from space shuttle actuator bearings. Experiments were performed on a test rig under simulated conditions to determine the life and failure mechanism of the grease lubricated bearings that support the input shaft of the space shuttle body flap actuators. The failure mechanism was wear that can cause loss of bearing preload. These tests established life and reliability data for both shuttle flight and ground operation. Test data were used to estimate the failure rate and reliability as a function of the number of shuttle missions flown. The Weibull analysis of the test data for the four actuators on one shuttle, each with a 2-bearing shaft assembly, established a reliability level of 96.9 percent for a life of 12 missions. A probabilistic system analysis for four shuttles, each of which has four actuators, predicts a single bearing failure in one actuator of one shuttle after 22 missions (a total of 88 missions for a 4-shuttle fleet). This prediction is comparable with actual shuttle flight history in which a single actuator bearing was found to have failed by wear at 20 missions.

Changes to the shuttle circuits

CERN Multimedia

GS Department

2011-01-01

To fit with passengers expectation, there will be some changes to the shuttle circuits as from Monday 10 October. See details on http://cern.ch/ShuttleService (on line on 7 October). Circuit No. 5 is cancelled as circuit No. 1 also stops at Bldg. 33. In order to guarantee shorter travel times, circuit No. 1 will circulate on Meyrin site only and circuit No. 2, with departures from Bldg. 33 and 500, on Prévessin site only. Site Services Section

Proton decay: spectroscopic probe beyond the proton drip line

International Nuclear Information System (INIS)

Seweryniak, D; Davids, C N; Robinson, A; Woods, P J; Blank, B; Carpenter, M P; Davinson, T; Freeman, S J; Hammond, N; Hoteling, N; Janssens, R V F; Khoo, T L; Liu, Z; Mukherjee, G; Shergur, J; Sinha, S; Sonzogni, A A; Walters, W B; Woehr, A

2005-01-01

Proton decay has been transformed in recent years from an exotic phenomenon into a powerful spectroscopic tool. The frontiers of experimental and theoretical proton-decay studies will be reviewed. Different aspects of proton decay will be illustrated with recent results on the deformed proton emitter 135 Tb, the odd-odd deformed proton emitter 130 Eu, the complex fine structure in the odd-odd 146 Tm nucleus and on excited states in the transitional proton emitter 145 Tm

A Shuttle Derived Vehicle launch system

Science.gov (United States)

Tewell, J. R.; Buell, D. N.; Ewing, E. S.

1982-01-01

This paper describes a Shuttle Derived Vehicle (SDV) launch system presently being studied for the NASA by Martin Marietta Aerospace which capitalizes on existing Shuttle hardware elements to provide increased accommodations for payload weight, payload volume, or both. The SDV configuration utilizes the existing solid rocket boosters, external tank and the Space Shuttle main engines but replaces the manned orbiter with an unmanned, remotely controlled cargo carrier. This cargo carrier substitution more than doubles the performance capability of the orbiter system and is realistically achievable for minimal cost. The advantages of the SDV are presented in terms of performance and economics. Based on these considerations, it is concluded that an unmanned SDV offers a most attractive complement to the present Space Transportation System.

Proton imaging apparatus for proton therapy application

International Nuclear Information System (INIS)

Sipala, V.; Lo Presti, D.; Brianzi, M.; Civinini, C.; Bruzzi, M.; Scaringella, M.; Talamonti, C.; Bucciolini, M.; Cirrone, G.A.P.; Cuttone, G.; Randazzo, N.; Stancampiano, C.; Tesi, M.

2011-01-01

Radiotherapy with protons, due to the physical properties of these particles, offers several advantages for cancer therapy as compared to the traditional radiotherapy and photons. In the clinical use of proton beams, a p CT (Proton Computer Tomography) apparatus can contribute to improve the accuracy of the patient positioning and dose distribution calculation. In this paper a p CT apparatus built by the Prima (Proton Imaging) Italian Collaboration will be presented and the preliminary results will be discussed.

Quantum mechanical models for the Fermi shuttle

Science.gov (United States)

Sternberg, James; Ovchinnikov, S. Yu.; Macek, J. H.

2009-05-01

Although the Fermi shuttle was originally proposed as an explanation for highly energetic cosmic rays, it is also a mechanism for the production of high energy electrons in atomic collisions [1]. The Fermi shuttle is usually thought of as a classical effect and most models of this process rely on classical or semi-classical approximations. In this work we explore several quantum mechanical models for ion-atom collisions and examine the evidence for the Fermi shuttle in these models. [4pt] [1] B. Sulik, Cs. Koncz, K. Tok'esi, A. Orb'an, and D. Ber'enyi, Phys Rev. Lett. 88 073201 (2002)

Fundamental plant biology enabled by the space shuttle.

Science.gov (United States)

Paul, Anna-Lisa; Wheeler, Ray M; Levine, Howard G; Ferl, Robert J

2013-01-01

The relationship between fundamental plant biology and space biology was especially synergistic in the era of the Space Shuttle. While all terrestrial organisms are influenced by gravity, the impact of gravity as a tropic stimulus in plants has been a topic of formal study for more than a century. And while plants were parts of early space biology payloads, it was not until the advent of the Space Shuttle that the science of plant space biology enjoyed expansion that truly enabled controlled, fundamental experiments that removed gravity from the equation. The Space Shuttle presented a science platform that provided regular science flights with dedicated plant growth hardware and crew trained in inflight plant manipulations. Part of the impetus for plant biology experiments in space was the realization that plants could be important parts of bioregenerative life support on long missions, recycling water, air, and nutrients for the human crew. However, a large part of the impetus was that the Space Shuttle enabled fundamental plant science essentially in a microgravity environment. Experiments during the Space Shuttle era produced key science insights on biological adaptation to spaceflight and especially plant growth and tropisms. In this review, we present an overview of plant science in the Space Shuttle era with an emphasis on experiments dealing with fundamental plant growth in microgravity. This review discusses general conclusions from the study of plant spaceflight biology enabled by the Space Shuttle by providing historical context and reviews of select experiments that exemplify plant space biology science.

Measurement of small-angle antiproton-proton and proton-proton elastic scattering at the CERN intersecting storage rings

NARCIS (Netherlands)

Amos, N.; Block, M.M.; Bobbink, G.J.; Botje, M.A.J.; Favart, D.; Leroy, C.; Linde, F.; Lipnik, P.; Matheys, J-P.; Miller, D.

1985-01-01

Antiproton-proton and proton-proton small-angle elastic scattering was measured for centre-of-mass energies at the CERN Intersectung Storage Rings. In addition, proton-proton elastic scattering was measured at . Using the optical theorem, total cross sections are obtained with an accuracy of about

Shuttle SBUV (SSBUV) Solar Spectral Irradiance V008

Data.gov (United States)

National Aeronautics and Space Administration — The Shuttle Solar Backscatter Ultraviolet (SSBUV) level-2 irradiance data are available for eight space shuttle missions flown between 1989 and 1996. SSBUV, a...

AMS gets lift on space shuttle Discovery

CERN Multimedia

2009-01-01

AMS-02, the CERN-recognized experiment that will seek dark matter, missing matter and antimatter in Space aboard the International Space Station (ISS), has recently got the green light to be part of the STS-134 NASA mission in 2010. Installation of AMS detectors in the Prévessin experiment hall.In a recent press release, NASA announced that the last or last-but-one mission of the Space Shuttle programme would be the one that will deliver AMS, the Alpha Magnetic Spectrometer, to the International Space Station. The Space Shuttle Discovery is due to lift off in July 2010 from Kennedy Space Center and its mission will include the installation of AMS to the exterior of the space station, using both the shuttle and station arms. "It wasn’t easy to get a lift on the Space Shuttle from the Bush administration," says professor Samuel Ting, spokesperson of the experiment, "since during his administration all the funds for space research w...

The space shuttle program technologies and accomplishments

CERN Document Server

Sivolella, Davide

2017-01-01

This book tells the story of the Space Shuttle in its many different roles as orbital launch platform, orbital workshop, and science and technology laboratory. It focuses on the technology designed and developed to support the missions of the Space Shuttle program. Each mission is examined, from both the technical and managerial viewpoints. Although outwardly identical, the capabilities of the orbiters in the late years of the program were quite different from those in 1981. Sivolella traces the various improvements and modifications made to the shuttle over the years as part of each mission story. Technically accurate but with a pleasing narrative style and simple explanations of complex engineering concepts, the book provides details of many lesser known concepts, some developed but never flown, and commemorates the ingenuity of NASA and its partners in making each Space Shuttle mission push the boundaries of what we can accomplish in space. Using press kits, original papers, newspaper and magazine articles...

Shuttle sonic boom - Technology and predictions. [environmental impact

Science.gov (United States)

Holloway, P. F.; Wilhold, G. A.; Jones, J. H.; Garcia, F., Jr.; Hicks, R. M.

1973-01-01

Because the shuttle differs significantly in both geometric and operational characteristics from conventional supersonic aircraft, estimation of sonic boom characteristics required a new technology base. The prediction procedures thus developed are reviewed. Flight measurements obtained for both the ascent and entry phases of the Apollo 15 and 16 and for the ascent phase only of the Apollo 17 missions are presented which verify the techniques established for application to shuttle. Results of extensive analysis of the sonic boom overpressure characteristics completed to date are presented which indicate that this factor of the shuttle's environmental impact is predictable, localized, of short duration and acceptable. Efforts are continuing to define the shuttle sonic boom characteristics to a fine level of detail based on the final system design.

Electron shuttles in biotechnology.

Science.gov (United States)

Watanabe, Kazuya; Manefield, Mike; Lee, Matthew; Kouzuma, Atsushi

2009-12-01

Electron-shuttling compounds (electron shuttles [ESs], or redox mediators) are essential components in intracellular electron transfer, while microbes also utilize self-produced and naturally present ESs for extracellular electron transfer. These compounds assist in microbial energy metabolism by facilitating electron transfer between microbes, from electron-donating substances to microbes, and/or from microbes to electron-accepting substances. Artificially supplemented ESs can create new routes of electron flow in the microbial energy metabolism, thereby opening up new possibilities for the application of microbes to biotechnology processes. Typical examples of such processes include halogenated-organics bioremediation, azo-dye decolorization, and microbial fuel cells. Herein we suggest that ESs can be applied widely to create new microbial biotechnology processes.

On proton CT reconstruction using MVCT-converted virtual proton projections

Energy Technology Data Exchange (ETDEWEB)

Wang Dongxu; Mackie, T. Rockwell; Tome, Wolfgang A. [Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705 and Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 (United States); Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705 and Morgridge Institute of Research, University of Wisconsin, Madison, Wisconsin 53715 (United States); Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705 and Oncophysics Institute, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461 (United States)

2012-06-15

Purpose: To describe a novel methodology of converting megavoltage x-ray projections into virtual proton projections that are otherwise missing due to the proton range limit. These converted virtual proton projections can be used in the reconstruction of proton computed tomography (pCT). Methods: Relations exist between proton projections and multispectral megavoltage x-ray projections for human tissue. Based on these relations, these tissues can be categorized into: (a) adipose tissue; (b) nonadipose soft tissues; and (c) bone. These three tissue categories can be visibly identified on a regular megavoltage x-ray computed tomography (MVCT) image. With an MVCT image and its projection data available, the x-ray projections through heterogeneous anatomy can be converted to the corresponding proton projections using predetermined calibration curves for individual materials, aided by a coarse segmentation on the x-ray CT image. To show the feasibility of this approach, mathematical simulations were carried out. The converted proton projections, plotted on a proton sinogram, were compared to the simulated ground truth. Proton stopping power images were reconstructed using either the virtual proton projections only or a blend of physically available proton projections and virtual proton projections that make up for those missing due to the range limit. These images were compared to a reference image reconstructed from theoretically calculated proton projections. Results: The converted virtual projections had an uncertainty of {+-}0.8% compared to the calculated ground truth. Proton stopping power images reconstructed using a blend of converted virtual projections (48%) and physically available projections (52%) had an uncertainty of {+-}0.86% compared with that reconstructed from theoretically calculated projections. Reconstruction solely from converted virtual proton projections had an uncertainty of {+-}1.1% compared with that reconstructed from theoretical projections

On proton CT reconstruction using MVCT-converted virtual proton projections

International Nuclear Information System (INIS)

Wang Dongxu; Mackie, T. Rockwell; Tomé, Wolfgang A.

2012-01-01

Purpose: To describe a novel methodology of converting megavoltage x-ray projections into virtual proton projections that are otherwise missing due to the proton range limit. These converted virtual proton projections can be used in the reconstruction of proton computed tomography (pCT). Methods: Relations exist between proton projections and multispectral megavoltage x-ray projections for human tissue. Based on these relations, these tissues can be categorized into: (a) adipose tissue; (b) nonadipose soft tissues; and (c) bone. These three tissue categories can be visibly identified on a regular megavoltage x-ray computed tomography (MVCT) image. With an MVCT image and its projection data available, the x-ray projections through heterogeneous anatomy can be converted to the corresponding proton projections using predetermined calibration curves for individual materials, aided by a coarse segmentation on the x-ray CT image. To show the feasibility of this approach, mathematical simulations were carried out. The converted proton projections, plotted on a proton sinogram, were compared to the simulated ground truth. Proton stopping power images were reconstructed using either the virtual proton projections only or a blend of physically available proton projections and virtual proton projections that make up for those missing due to the range limit. These images were compared to a reference image reconstructed from theoretically calculated proton projections. Results: The converted virtual projections had an uncertainty of ±0.8% compared to the calculated ground truth. Proton stopping power images reconstructed using a blend of converted virtual projections (48%) and physically available projections (52%) had an uncertainty of ±0.86% compared with that reconstructed from theoretically calculated projections. Reconstruction solely from converted virtual proton projections had an uncertainty of ±1.1% compared with that reconstructed from theoretical projections. If

DIMETHYL ETHER (DME)-FUELED SHUTTLE BUS DEMONSTRATION PROJECT

Energy Technology Data Exchange (ETDEWEB)

Elana M. Chapman; Shirish Bhide; Jennifer Stefanik; Howard Glunt; Andre L. Boehman; Allen Homan; David Klinikowski

2003-04-01

The objectives of this research and demonstration program are to convert a campus shuttle bus to operation on dimethyl ether, a potential ultra-clean alternative diesel fuel. To accomplish this objective, this project includes laboratory evaluation of a fuel conversion strategy, as well as, field demonstration of the DME-fueled shuttle bus. Since DME is a fuel with no lubricity (i.e., it does not possess the lubricating quality of diesel fuel), conventional fuel delivery and fuel injection systems are not compatible with dimethylether. Therefore, to operate a diesel engine on DME one must develop a fuel-tolerant injection system, or find a way to provide the necessary lubricity to the DME. In this project, they have chosen the latter strategy in order to achieve the objective with minimal need to modify the engine. The strategy is to blend DME with diesel fuel, to obtain the necessary lubricity to protect the fuel injection system and to achieve low emissions. The bulk of the efforts over the past year were focused on the conversion of the campus shuttle bus. This process, started in August 2001, took until April 2002 to complete. The process culminated in an event to celebrate the launching of the shuttle bus on DME-diesel operation on April 19, 2002. The design of the system on the shuttle bus was patterned after the system developed in the engine laboratory, but also was subjected to a rigorous failure modes effects analysis with help from Dr. James Hansel of Air Products. The result of this FMEA was the addition of layers of redundancy and over-pressure protection to the system on the shuttle bus. The system became operation in February 2002. Preliminary emissions tests and basic operation of the shuttle bus took place at the Pennsylvania Transportation institute's test track facility near the University Park airport. After modification and optimization of the system on the bus, operation on the campus shuttle route began in early June 2002. However, the

Revised estimates for ozone reduction by shuttle operation

Science.gov (United States)

Potter, A. E.

1978-01-01

Previous calculations by five different modeling groups of the effect of space shuttle operations on the ozone layer yielded an estimate of 0.2 percent ozone reduction for the Northern Hemisphere at 60 launches per year. Since these calculations were made, the accepted rate constant for the reaction between hydroperoxyl and nitric oxide to yield hydroxyl and nitrogen dioxide, HO2 + NO yields OH + NO2, was revised upward by more than an order of magnitude, with a resultant increase in the predicted ozone reduction for chlorofluoromethanes by a factor of approximately 2. New calculations of the shuttle effect were made with use of the new rate constant data, again by five different modeling groups. The new value of the shuttle effect on the ozone layer was found to be 0.25 percent. The increase resulting from the revised rate constant is considerably less for space shuttle operations than for chlorofluoromethane production, because the new rate constant also increases the calculated rate of downward transport of shuttle exhaust products out of the stratosphere.

Selective Nitrate Recognition by a Halogen‐Bonding Four‐Station [3]Rotaxane Molecular Shuttle

Science.gov (United States)

Barendt, Timothy A.; Docker, Andrew; Marques, Igor; Félix, Vítor

2016-01-01

Abstract The synthesis of the first halogen bonding [3]rotaxane host system containing a bis‐iodo triazolium‐bis‐naphthalene diimide four station axle component is reported. Proton NMR anion binding titration experiments revealed the halogen bonding rotaxane is selective for nitrate over the more basic acetate, hydrogen carbonate and dihydrogen phosphate oxoanions and chloride, and exhibits enhanced recognition of anions relative to a hydrogen bonding analogue. This elaborate interlocked anion receptor functions via a novel dynamic pincer mechanism where upon nitrate anion binding, both macrocycles shuttle from the naphthalene diimide stations at the periphery of the axle to the central halogen bonding iodo‐triazolium station anion recognition sites to form a unique 1:1 stoichiometric nitrate anion–rotaxane sandwich complex. Molecular dynamics simulations carried out on the nitrate and chloride halogen bonding [3]rotaxane complexes corroborate the 1H NMR anion binding results. PMID:27436297

DIMETHYL ETHER (DME)-FUELED SHUTTLE BUS DEMONSTRATION PROJECT

Energy Technology Data Exchange (ETDEWEB)

Elana M. Chapman; Shirish Bhide; Jennifer Stefanik; Howard Glunt; Andre L. Boehman; Allen Homan; David Klinikowski

2003-04-01

The objectives of this research and demonstration program are to convert a campus shuttle bus to operation on dimethyl ether, a potential ultra-clean alternative diesel fuel. To accomplish this objective, this project includes laboratory evaluation of a fuel conversion strategy, as well as, field demonstration of the DME-fueled shuttle bus. Since DME is a fuel with no lubricity (i.e., it does not possess the lubricating quality of diesel fuel), conventional fuel delivery and fuel injection systems are not compatible with dimethyl ether. Therefore, to operate a diesel engine on DME one must develop a fuel-tolerant injection system, or find a way to provide the necessary lubricity to the DME. In this project, they have chosen the latter strategy in order to achieve the objective with minimal need to modify the engine. Their strategy is to blend DME with diesel fuel, to obtain the necessary lubricity to protect the fuel injection system and to achieve low emissions. The bulk of the efforts over the past year were focused on the conversion of the campus shuttle bus. This process, started in August 2001, took until April 2002 to complete. The process culminated in an event to celebrate the launching of the shuttle bus on DME-diesel operation on April 19, 2002. The design of the system on the shuttle bus was patterned after the system developed in the engine laboratory, but also was subjected to a rigorous failure modes effects analysis (FMEA, referred to by Air Products as a ''HAZOP'' analysis) with help from Dr. James Hansel of Air Products. The result of this FMEA was the addition of layers of redundancy and over-pressure protection to the system on the shuttle bus. The system became operational in February 2002. Preliminary emissions tests and basic operation of the shuttle bus took place at the Pennsylvania Transportation Institute's test track facility near the University Park airport. After modification and optimization of the system on

Shuttle bus services quality assessment Tangerang Selatan toward smart city

Science.gov (United States)

Fassa, Ferdinand; Sitorus, Fredy Jhon Philip; Adikesuma, Tri Nugraha

2017-11-01

Around the world, shuttle bus operation played the significant role to accommodate transportation for commuting bus passengers. Shuttle Bus services in cities are provided by various bus agencies with kinds of own specific purposes. For instance, at Tangerang Selatan, Indonesia, it was said that shuttle bus In Trans Bintaro is run and operated by private bus companies hire by Bintaro developer. The aim of this research is to identify factors of satisfaction of shuttle bus service in Kota Tangerang Selatan, Indonesia. Several factors are used to analyze sums of 20 parameters performance indicators of Shuttle Bus. A face to face interview using a questionnaire (N=200) was used to collect data on October and March 2017. Likert and diagram Cartesian were used to model the all the parameters. This research succeeded in finding some categories of Shuttle bus service attributes such as accessibility, comfort, and safety. Users agreed that eight indicators in shuttle bus have the excellent achievement, while three indicators on performance remain low and should receive more attention especially punctuality of the bus.

Shuttle/TDRSS modelling and link simulation study

Science.gov (United States)

Braun, W. R.; Mckenzie, T. M.; Biederman, L.; Lindsey, W. C.

1979-01-01

A Shuttle/TDRSS S-band and Ku-band link simulation package called LinCsim was developed for the evaluation of link performance for specific Shuttle signal designs. The link models were described in detail and the transmitter distortion parameters or user constraints were carefully defined. The overall link degradation (excluding hardware degradations) relative to an ideal BPSK channel were given for various sets of user constraint values. The performance sensitivity to each individual user constraint was then illustrated. The effect of excessive Spacelab clock jitter on the return link BER performance was also investigated as was the problem of subcarrier recovery for the K-band Shuttle return link signal.

Optimal Wafer Cutting in Shuttle Layout Problems

DEFF Research Database (Denmark)

Nisted, Lasse; Pisinger, David; Altman, Avri

2011-01-01

. The shuttle layout problem is frequently solved in two phases: first, a floorplan of the shuttle is generated. Then, a cutting plan is found which minimizes the overall number of wafers needed to satisfy the demand of each die type. Since some die types require special production technologies, only compatible...

Astronaut exposure to space radiation - Space Shuttle experience

International Nuclear Information System (INIS)

Atwell, W.

1990-01-01

Space Shuttle astronauts are exposed to both the trapped radiation and the galactic cosmic radiation environments. In addition, the sun periodically emits high-energy particles which could pose a serious threat to flight crews. NASA adheres to federal regulations and recommended exposure limits for radiation protection and has established a radiological health and risk assessment program. Using models of the space radiation environment, a Shuttle shielding model, and an anatomical human model, crew exposure estimates are made for each Shuttle flight. The various models are reviewed. Dosimeters are worn by each astronaut and are flown at several fixed locations to obtain inflight measurements. The dosimetry complement is discussed in detail. A comparison between the premission calculations and measurements is presented. Extrapolation of Shuttle experience to long-duration exposure is explored. 14 refs

Shuttle Transportation System Case-Study Development

Science.gov (United States)

Ransom, Khadijah

2012-01-01

A case-study collection was developed for NASA's Space Shuttle Program. Using lessons learned and documented by NASA KSC engineers, analysts, and contractors, decades of information related to processing and launching the Space Shuttle was gathered into a single database. The goal was to provide educators with an alternative means to teach real-world engineering processes and to enhance critical thinking, decision making, and problem solving skills. Suggested formats were created to assist both external educators and internal NASA employees to develop and contribute their own case-study reports to share with other educators and students. Via group project, class discussion, or open-ended research format, students will be introduced to the unique decision making process related to Shuttle missions and development. Teaching notes, images, and related documents will be made accessible to the public for presentation of Space Shuttle reports. Lessons investigated included the engine cutoff (ECO) sensor anomaly which occurred during mission STS-114. Students will be presented with general mission infom1ation as well as an explanation of ECO sensors. The project will conclude with the design of a website that allows for distribution of information to the public as well as case-study report submissions from other educators online.

Electrolytic conductivity-the hopping mechanism of the proton and beyond

International Nuclear Information System (INIS)

Gileadi, E.; Kirowa-Eisner, E.

2006-01-01

The hopping mechanism of electrolytic conductivity is analyzed, employing mixtures of two solvents: one that sustains the hopping mechanism and the other that does not inhibit it directly, but interferes with it by diluting the solvent that sustains hopping. Measurement of the equivalent conductivity shows that the excess proton conductivities of H 3 O + and OH - increases with increasing temperature, although the number of hydrogen bonds is known to decrease. In mixtures of acetonitrile with water, proton hopping does not start until a threshold concentration of about 20 vol.% water has been reached, while no such threshold concentration is observed upon addition of methanol to acetonitrile. It is concluded that in the former the proton is transferred to a cluster of water molecules, which can be formed only if there is enough water in the solvent mixture. This observation leads to the concept of mono-water, which is the state of water molecules when they constitute a small minority in the solvent mixtures, as opposed to bulk water, which consists of clusters of variable sizes. Systems in which a hopping mechanism of heavy ions has been observed include Br - /Br 2 and I - /I 2 . In these cases the triple ions Br 3 - and I 3 - , respectively are formed, and serve as the mediators for the transfer of the simple halogen ion. A very large increase of conductivity was observed upon solidification of the Br - /Br 3 - system, probably caused by favorable linear alignment of ions in the solid. The conductivity of acidified methanol decreases upon addition of water, because the affinity of the proton to water is higher than to methanol, thus water can act as a scavenger for protons. This behavior exemplifies a general observation, namely that conductivity by hopping can only occur when the Gibbs energy of the system does not change significantly following ion transfer; otherwise the ions would be trapped in the more stable state, hindering further propagation by hopping

Liquid Hydrogen Consumption During Space Shuttle Program

Science.gov (United States)

Partridge, Jonathan K.

2011-01-01

This slide presentation reviews the issue of liquid hydrogen consumption and the points of its loss in prior to the shuttle launch. It traces the movement of the fuel from the purchase to the on-board quantity and the loss that results in 54.6 of the purchased quantity being on board the Shuttle.

The Rules and Functions of Nucleocytoplasmic Shuttling Proteins.

Science.gov (United States)

Fu, Xuekun; Liang, Chao; Li, Fangfei; Wang, Luyao; Wu, Xiaoqiu; Lu, Aiping; Xiao, Guozhi; Zhang, Ge

2018-05-12

Biological macromolecules are the basis of life activities. There is a separation of spatial dimension between DNA replication and RNA biogenesis, and protein synthesis, which is an interesting phenomenon. The former occurs in the cell nucleus, while the latter in the cytoplasm. The separation requires protein to transport across the nuclear envelope to realize a variety of biological functions. Nucleocytoplasmic transport of protein including import to the nucleus and export to the cytoplasm is a complicated process that requires involvement and interaction of many proteins. In recent years, many studies have found that proteins constantly shuttle between the cytoplasm and the nucleus. These shuttling proteins play a crucial role as transport carriers and signal transduction regulators within cells. In this review, we describe the mechanism of nucleocytoplasmic transport of shuttling proteins and summarize some important diseases related shuttling proteins.

AI mass spectrometers for space shuttle health monitoring

Science.gov (United States)

Adams, F. W.

1991-01-01

The facility Hazardous Gas Detection System (HGDS) at Kennedy Space Center (KSC) is a mass spectrometer based gas analyzer. Two instruments make up the HGDS, which is installed in a prime/backup arrangement, with the option of using both analyzers on the same sample line, or on two different lines simultaneously. It is used for monitoring the Shuttle during fuel loading, countdown, and drainback, if necessary. The use of complex instruments, operated over many shifts, has caused problems in tracking the status of the ground support equipment (GSE) and the vehicle. A requirement for overall system reliability has been a major force in the development of Shuttle GSE, and is the ultimate driver in the choice to pursue artificial intelligence (AI) techniques for Shuttle and Advanced Launch System (ALS) mass spectrometer systems. Shuttle applications of AI are detailed.

The flights before the flight - An overview of shuttle astronaut training

Science.gov (United States)

Sims, John T.; Sterling, Michael R.

1989-01-01

Space shuttle astronaut training is centered at NASA's Johnson Space Center in Houston, Texas. Each astronaut receives many different types of training from many sources. This training includes simulator training in the Shuttle Mission Simulator, in-flight simulator training in the Shuttle Training Aircraft, Extravehicular Activity training in the Weightless Environment Training Facility and a variety of lectures and briefings. Once the training program is completed each shuttle flight crew is well-prepared to perform the normal operations required for their flight and deal with any shuttle system malfunctions that might occur.

Shuttle Repair Tools Automate Vehicle Maintenance

Science.gov (United States)

2013-01-01

Successfully building, flying, and maintaining the space shuttles was an immensely complex job that required a high level of detailed, precise engineering. After each shuttle landed, it entered a maintenance, repair, and overhaul (MRO) phase. Each system was thoroughly checked and tested, and worn or damaged parts replaced, before the shuttle was rolled out for its next mission. During the MRO period, workers needed to record exactly what needed replacing and why, as well as follow precise guidelines and procedures in making their repairs. That meant traceability, and with it lots of paperwork. In 2007, the number of reports generated during electrical system repairs was getting out of hand-placing among the top three systems in terms of paperwork volume. Repair specialists at Kennedy Space Center were unhappy spending so much time at a desk and so little time actually working on the shuttle. "Engineers weren't spending their time doing technical work," says Joseph Schuh, an electrical engineer at Kennedy. "Instead, they were busy with repetitive, time-consuming processes that, while important in their own right, provided a low return on time invested." The strain of such inefficiency was bad enough that slow electrical repairs jeopardized rollout on several occasions. Knowing there had to be a way to streamline operations, Kennedy asked Martin Belson, a project manager with 30 years experience as an aerospace contractor, to co-lead a team in developing software that would reduce the effort required to document shuttle repairs. The result was System Maintenance Automated Repair Tasks (SMART) software. SMART is a tool for aggregating and applying information on every aspect of repairs, from procedures and instructions to a vehicle s troubleshooting history. Drawing on that data, SMART largely automates the processes of generating repair instructions and post-repair paperwork. In the case of the space shuttle, this meant that SMART had 30 years worth of operations

CERN Shuttle

CERN Multimedia

General Infrastructure Services Department

2011-01-01

As of Monday 21 February, a new schedule will come into effect for the Airport Shuttle (circuit No. 4) at the end of the afternoon: Last departure at 7:00 pm from Main Buildig, (Bldg. 500) to Airport (instead of 5:10 p.m.); Last departure from Airport to CERN, Main Buildig, (Bldg. 500), at 7:30 p.m. (instead of 5:40 p.m.). Group GS-IS

An Opportunistic Wireless Charging System Design for an On-Demand Shuttle Service: Preprint

Energy Technology Data Exchange (ETDEWEB)

Doubleday, Kate; Meintz, Andrew; Markel, Tony

2016-08-01

System right-sizing is critical to implementation of in-motion wireless power transfer (WPT) for electric vehicles. This study introduces a modeling tool, WPTSim, which uses one-second speed, location, and road grade data from an on-demand employee shuttle in operation to simulate the incorporation of WPT at fine granularity. Vehicle power and state of charge are simulated over the drive cycle to evaluate potential system designs. The required battery capacity is determined based on the rated power at a variable number of charging locations. Adding just one WPT location can more than halve the battery capacity needed. Many configurations are capable of being self sustaining with WPT, while others benefit from supplemental stationary charging.

Macro Level Simulation Model Of Space Shuttle Processing

Science.gov (United States)

2000-01-01

The contents include: 1) Space Shuttle Processing Simulation Model; 2) Knowledge Acquisition; 3) Simulation Input Analysis; 4) Model Applications in Current Shuttle Environment; and 5) Model Applications for Future Reusable Launch Vehicles (RLV's). This paper is presented in viewgraph form.

STS-61 Space Shuttle mission report

Science.gov (United States)

Fricke, Robert W., Jr.

1994-02-01

The STS-61 Space Shuttle Program Mission Report summarizes the Hubble Space Telescope (HST) servicing mission as well as the Orbiter, External Tank (ET), Solid Rocket Booster (SRB), Redesigned Solid Rocket Motor (RSRM), and the Space Shuttle main engine (SSME) systems performance during the fifty-ninth flight of the Space Shuttle Program and fifth flight of the Orbiter vehicle Endeavour (OV-105). In addition to the Orbiter, the flight vehicle consisted of an ET designated as ET-60; three SSME's which were designated as serial numbers 2019, 2033, and 2017 in positions 1, 2, and 3, respectively; and two SRB's which were designated BI-063. The RSRM's that were installed in each SRB were designated as 360L023A (lightweight) for the left SRB, and 360L023B (lightweight) for the right SRB. This STS-61 Space Shuttle Program Mission Report fulfills the Space Shuttle Program requirement as documented in NSTS 07700, Volume 8, Appendix E. That document requires that each major organizational element supporting the Program report the results of its hardware evaluation and mission performance plus identify all related in-flight anomalies. The primary objective of the STS-61 mission was to perform the first on-orbit servicing of the Hubble Space Telescope. The servicing tasks included the installation of new solar arrays, replacement of the Wide Field/Planetary Camera I (WF/PC I) with WF/PC II, replacement of the High Speed Photometer (HSP) with the Corrective Optics Space Telescope Axial Replacement (COSTAR), replacement of rate sensing units (RSU's) and electronic control units (ECU's), installation of new magnetic sensing systems and fuse plugs, and the repair of the Goddard High Resolution Spectrometer (GHRS). Secondary objectives were to perform the requirements of the IMAX Cargo Bay Camera (ICBC), the IMAX Camera, and the Air Force Maui Optical Site (AMOS) Calibration Test.

Proton therapy

International Nuclear Information System (INIS)

Smith, Alfred R

2006-01-01

Proton therapy has become a subject of considerable interest in the radiation oncology community and it is expected that there will be a substantial growth in proton treatment facilities during the next decade. I was asked to write a historical review of proton therapy based on my personal experiences, which have all occurred in the United States, so therefore I have a somewhat parochial point of view. Space requirements did not permit me to mention all of the existing proton therapy facilities or the names of all of those who have contributed to proton therapy. (review)

Proton-proton bremsstrahlung in a relativistic covariant model

NARCIS (Netherlands)

Martinus, Gerard Henk

1998-01-01

Proton-proton bremsstrahlung is one of the simplest processes involving the half off-shell NN interaction. Since protons are equally-charged particles with the same mass, electric-dipole radiation is suppressed and higher-order effects play an important role. Thus it is possible to get information

Wings In Orbit: Scientific and Engineering Legacies of the Space Shuttle

Science.gov (United States)

Hale, N. Wayne (Editor); Lulla, Kamlesh (Editor); Lane, Helen W. (Editor); Chapline, Gail (Editor)

2010-01-01

This Space Shuttle book project reviews Wings In Orbit-scientific and engineering legacies of the Space Shuttle. The contents include: 1) Magnificent Flying Machine-A Cathedral to Technology; 2) The Historical Legacy; 3) The Shuttle and its Operations; 4) Engineering Innovations; 5) Major Scientific Discoveries; 6) Social, Cultural, and Educational Legacies; 7) Commercial Aerospace Industries and Spin-offs; and 8) The Shuttle continuum, Role of Human Spaceflight.

Proton-Proton and Proton-Antiproton Colliders

CERN Document Server

Scandale, Walter

2014-01-01

In the last five decades, proton–proton and proton–antiproton colliders have been the most powerful tools for high energy physics investigations. They have also deeply catalyzed innovation in accelerator physics and technology. Among the large number of proposed colliders, only four have really succeeded in becoming operational: the ISR, the SppbarS, the Tevatron and the LHC. Another hadron collider, RHIC, originally conceived for ion–ion collisions, has also been operated part-time with polarized protons. Although a vast literature documenting them is available, this paper is intended to provide a quick synthesis of their main features and key performance.

Dynamics of Anti-Proton -- Protons and Anti-Proton -- Nucleus Reactions

CERN Document Server

Galoyan, A; Uzhinsky, V

2016-01-01

A short review of simulation results of anti-proton-proton and anti-proton-nucleus interactions within the framework of Geant4 FTF (Fritiof) model is presented. The model uses the main assumptions of the Quark-Gluon-String Model or Dual Parton Model. The model assumes production and fragmentation of quark-anti-quark and diquark-anti-diquark strings in the mentioned interactions. Key ingredients of the model are cross sections of string creation processes and an usage of the LUND string fragmentation algorithm. They allow one to satisfactory describe a large set of experimental data, especially, a strange particle production, Lambda hyperons and K mesons.

Stennis Holds Last Planned Space Shuttle Engine Test

Science.gov (United States)

2009-01-01

With 520 seconds of shake, rattle and roar on July 29, 2009 NASA's John C. Stennis Space Center marked the end of an era for testing the space shuttle main engines that have powered the nation's Space Shuttle Program for nearly three decades.

Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes?

Science.gov (United States)

Rothman, Douglas L; De Feyter, Henk M; Maciejewski, Paul K; Behar, Kevin L

2012-11-01

The high in vivo flux of the glutamate/glutamine cycle puts a strong demand on the return of ammonia released by phosphate activated glutaminase from the neurons to the astrocytes in order to maintain nitrogen balance. In this paper we review several amino acid shuttles that have been proposed for balancing the nitrogen flows between neurons and astrocytes in the glutamate/glutamine cycle. All of these cycles depend on the directionality of glutamate dehydrogenase, catalyzing reductive glutamate synthesis (forward reaction) in the neuron in order to capture the ammonia released by phosphate activated glutaminase, while catalyzing oxidative deamination of glutamate (reverse reaction) in the astrocytes to release ammonia for glutamine synthesis. Reanalysis of results from in vivo experiments using (13)N and (15)N labeled ammonia and (15)N leucine in rats suggests that the maximum flux of the alanine/lactate or branched chain amino acid/branched chain amino acid transaminase shuttles between neurons and astrocytes are approximately 3-5 times lower than would be required to account for the ammonia transfer from neurons to astrocytes needed for glutamine synthesis (amide nitrogen) to sustain the glutamate/glutamine cycle. However, in the rat brain both the total ammonia fixation rate by glutamate dehydrogenase and the total branched chain amino acid transaminase activity are sufficient to support a branched chain amino acid/branched chain keto acid shuttle, as proposed by Hutson and coworkers, which would support the de novo synthesis of glutamine in the astrocyte to replace the ~20 % of neurotransmitter glutamate that is oxidized. A higher fraction of the nitrogen needs of total glutamate neurotransmitter cycling could be supported by hybrid cycles in which glutamate and tricarboxylic acid cycle intermediates act as a nitrogen shuttle. A limitation of all in vivo studies in animals conducted to date is that none have shown transfer of nitrogen for glutamine amide

A low earth orbit dynamic model for the proton anisotropy validation

Science.gov (United States)

Badavi, Francis F.

2011-11-01

Ionizing radiation measurements at low earth orbit (LEO) form the ideal tool for the experimental validation of radiation environmental models, nuclear transport code algorithms and nuclear reaction cross sections. Indeed, prior measurements on the space transportation system (STS; shuttle) have provided vital information impacting both the environmental models and the nuclear transport code development by requiring dynamic models of the LEO environment. Previous studies using computer aided design (CAD) models of the international space station (ISS) have demonstrated that the dosimetric prediction for a spacecraft at LEO requires the description of an environmental model with accurate anisotropic as well as dynamic behavior. This paper describes such a model for the trapped proton. The described model is a component of a suite of codes collectively named GEORAD (GEOmagnetic RADiation) which computes cutoff rigidity, trapped proton and trapped electron environments. The web version of GEORAD is named OLTARIS (On-line Tool for the Assessment of Radiation in Space). GEORAD suite is applicable to radiation environment prediction at LEO, medium earth orbit (MEO) and geosynchronous earth orbit (GEO) at quiet solar periods. GEORAD interest is in the study of long term effect of the trapped environment and therefore it does not account for any short term external field contribution due to solar activity. With the concentration of the paper on the LEO protons only, the paper presents the validation of the trapped proton model within GEORAD with reported measurements from the compact environment anomaly sensor (CEASE) science instrument package, flown onboard the tri-service experiment-5 (TSX-5) satellite during the period of June 2000 to July 2006. The spin stabilized satellite was flown in a 410 × 1710 km, 69° inclination elliptical orbit, allowing it to be exposed to a broad range of the LEO regime. The paper puts particular emphasize on the validation of the

Selective Nitrate Recognition by a Halogen-Bonding Four-Station [3]Rotaxane Molecular Shuttle.

Science.gov (United States)

Barendt, Timothy A; Docker, Andrew; Marques, Igor; Félix, Vítor; Beer, Paul D

2016-09-05

The synthesis of the first halogen bonding [3]rotaxane host system containing a bis-iodo triazolium-bis-naphthalene diimide four station axle component is reported. Proton NMR anion binding titration experiments revealed the halogen bonding rotaxane is selective for nitrate over the more basic acetate, hydrogen carbonate and dihydrogen phosphate oxoanions and chloride, and exhibits enhanced recognition of anions relative to a hydrogen bonding analogue. This elaborate interlocked anion receptor functions via a novel dynamic pincer mechanism where upon nitrate anion binding, both macrocycles shuttle from the naphthalene diimide stations at the periphery of the axle to the central halogen bonding iodo-triazolium station anion recognition sites to form a unique 1:1 stoichiometric nitrate anion-rotaxane sandwich complex. Molecular dynamics simulations carried out on the nitrate and chloride halogen bonding [3]rotaxane complexes corroborate the (1) H NMR anion binding results. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Shuttles set for US Gulf lift off

Energy Technology Data Exchange (ETDEWEB)

DeLuca, Marshall

2002-09-01

The author reports on discussions with two US companies about plans for using shuttle tankers to transport oil from platforms in the Gulf of Mexico to US ports as an alternative to pipeline networks. This follows approval by the US Minerals Management Service for FPSOs in the Gulf. The companies are American Shuttle Tankers and Conoco-owned Seahorse Shuttling and Technology. Because the vessels will enter US ports and operate in US waters, they must conform with the US Jones Act: they must be US-built, US-flagged and manned by US crews. They must also be double-hulled. This increases cost and reduces market opportunities for the vessels outside the US. The article also considers the use of articulated tug barges as another option. (UK)

The Shuttle Cost and Price model

Science.gov (United States)

Leary, Katherine; Stone, Barbara

1983-01-01

The Shuttle Cost and Price (SCP) model was developed as a tool to assist in evaluating major aspects of Shuttle operations that have direct and indirect economic consequences. It incorporates the major aspects of NASA Pricing Policy and corresponds to the NASA definition of STS operating costs. An overview of the SCP model is presented and the cost model portion of SCP is described in detail. Selected recent applications of the SCP model to NASA Pricing Policy issues are presented.

Theoretical Analysis of Proton Relays in Electrochemical Proton-Coupled Electron Transfer

International Nuclear Information System (INIS)

Auer, Benjamin; Fernandez, Laura; Hammes-Schiffer, Sharon

2011-01-01

The coupling of long-range electron transfer to proton transport over multiple sites plays a vital role in many biological and chemical processes. Recently a molecule with a hydrogen-bond relay inserted between the proton donor and acceptor sites in a proton-coupled electron transfer (PCET) system was studied electrochemically. The standard rate constants and kinetic isotope effects (KIEs) were measured experimentally for this system and a related single proton transfer system. In the present paper, these systems are studied theoretically using vibronically nonadiabatic rate constant expressions for electrochemical PCET. Application of this approach to proton relays requires the calculation of multidimensional proton vibrational wavefunctions and incorporation of multiple proton donor-acceptor motions. The calculated KIEs and relative standard rate constants for the single and double proton transfer systems are in agreement with the experimental data. The calculations indicate that the standard rate constant is lower for the double proton transfer system because of the smaller overlap integral between the ground state reduced and oxidized proton vibrational wavefunctions for this system, resulting in greater contributions from excited electron-proton vibronic states with higher free energy barriers. The decrease in proton donor-acceptor distances due to thermal fluctuations and the contributions from excited electron-proton vibronic states play important roles in proton relay systems. The theory suggests that the PCET rate constant may be increased by decreasing the equilibrium proton donor-acceptor distances or modifying the thermal motions of the molecule to facilitate the concurrent decrease of these distances. The submission of this journal article in ERIA is a requirement of the EFRC subcontract with Pennsylvania State University collaborators to get publications to OSTI.

Proton: the particle.

Science.gov (United States)

Suit, Herman

2013-11-01

The purpose of this article is to review briefly the nature of protons: creation at the Big Bang, abundance, physical characteristics, internal components, and life span. Several particle discoveries by proton as the experimental tool are considered. Protons play important roles in science, medicine, and industry. This article was prompted by my experience in the curative treatment of cancer patients by protons and my interest in the nature of protons as particles. The latter has been stimulated by many discussions with particle physicists and reading related books and journals. Protons in our universe number ≈10(80). Protons were created at 10(-6) -1 second after the Big Bang at ≈1.37 × 10(10) years beforethe present. Proton life span has been experimentally determined to be ≥10(34) years; that is, the age of the universe is 10(-24)th of the minimum life span of a proton. The abundance of the elements is hydrogen, ≈74%; helium, ≈24%; and heavier atoms, ≈2%. Accordingly, protons are the dominant baryonic subatomic particle in the universe because ≈87% are protons. They are in each atom in our universe and thus involved in virtually every activity of matter in the visible universe, including life on our planet. Protons were discovered in 1919. In 1968, they were determined to be composed of even smaller particles, principally quarks and gluons. Protons have been the experimental tool in the discoveries of quarks (charm, bottom, and top), bosons (W(+), W(-), Z(0), and Higgs), antiprotons, and antineutrons. Industrial applications of protons are numerous and important. Additionally, protons are well appreciated in medicine for their role in radiation oncology and in magnetic resonance imaging. Protons are the dominant baryonic subatomic particle in the visible universe, comprising ≈87% of the particle mass. They are present in each atom of our universe and thus a participant in every activity involving matter. Copyright © 2013 Elsevier Inc. All

Proton: The Particle

Energy Technology Data Exchange (ETDEWEB)

Suit, Herman

2013-11-01

The purpose of this article is to review briefly the nature of protons: creation at the Big Bang, abundance, physical characteristics, internal components, and life span. Several particle discoveries by proton as the experimental tool are considered. Protons play important roles in science, medicine, and industry. This article was prompted by my experience in the curative treatment of cancer patients by protons and my interest in the nature of protons as particles. The latter has been stimulated by many discussions with particle physicists and reading related books and journals. Protons in our universe number ≈10{sup 80}. Protons were created at 10{sup −6} –1 second after the Big Bang at ≈1.37 × 10{sup 10} years beforethe present. Proton life span has been experimentally determined to be ≥10{sup 34} years; that is, the age of the universe is 10{sup −24}th of the minimum life span of a proton. The abundance of the elements is hydrogen, ≈74%; helium, ≈24%; and heavier atoms, ≈2%. Accordingly, protons are the dominant baryonic subatomic particle in the universe because ≈87% are protons. They are in each atom in our universe and thus involved in virtually every activity of matter in the visible universe, including life on our planet. Protons were discovered in 1919. In 1968, they were determined to be composed of even smaller particles, principally quarks and gluons. Protons have been the experimental tool in the discoveries of quarks (charm, bottom, and top), bosons (W{sup +}, W{sup −}, Z{sup 0}, and Higgs), antiprotons, and antineutrons. Industrial applications of protons are numerous and important. Additionally, protons are well appreciated in medicine for their role in radiation oncology and in magnetic resonance imaging. Protons are the dominant baryonic subatomic particle in the visible universe, comprising ≈87% of the particle mass. They are present in each atom of our universe and thus a participant in every activity involving matter.

Antiproton-proton and proton-proton elastic scattering at 100 and 200 GeV/c

International Nuclear Information System (INIS)

Kaplan, D.H.; Karchin, P.; Orear, J.; Kalbach, R.M.; Krueger, K.W.; Pifer, A.E.; Baker, W.F.; Eartly, D.P.; Klinger, J.S.; Lennox, A.J.; Rubinstein, R.; McHugh, S.F.

1982-01-01

Antiproton-proton elastic scattering has been measured at 100 GeV/c for 0.5 2 and at 200 GeV/c for 0.9 2 . The data show that the -tapprox. =1.4 (GeV/c) 2 dip recently observed at 50 GeV/c persists to higher incident momenta. Proton-proton measurements made at the same beam momenta show similar structure

Proton decay theory

International Nuclear Information System (INIS)

Marciano, W.J.

1983-01-01

Topics include minimal SU(5) predictions, gauge boson mediated proton decay, uncertainties in tau/sub p/, Higgs scalar effects, proton decay via Higgs scalars, supersymmetric SU(5), dimension 5 operators and proton decay, and Higgs scalars and proton decay

High throughput study of fuel cell proton exchange membranes: Poly(vinylidene fluoride)/acrylic polyelectrolyte blends and nanocomposites with zirconium

Science.gov (United States)

Zapata B., Pedro Jose

Sustainability is perhaps one of the most heard buzzwords in the post-20 th century society; nevertheless, it is not without a reason. Our present practices for energy supply are largely unsustainable if we consider their environmental and social impact. In view of this unfavorable panorama, alternative sustainable energy sources and conversion approaches have acquired noteworthy significance in recent years. Among these, proton exchange membrane fuel cells (PEMFCs) are being considered as a pivotal building block in the transition towards a sustainable energy economy in the 21st century. The polyelectrolyte membrane or proton exchange membrane (PEM) is a vital component, as well as a performance-limiting factor, of the PEMFC. Consequently, the development of high-performance PEM materials is of utmost importance for the advance of the PEMFC field. In this work, alternative PEM materials based on semi-interpenetrated networks from blends of poly(vinyledene fluoride) (PVDF) (inert phase) and sulfonated crosslinked acrylic polyelectrolytes (PE) (proton-conducting phase), as well as tri-phase PVDF/PE/zirconium-based composites, are studied. To alleviate the burden resulting from the vast number of possible combinations of the different precursors utilized in the preparation of the membranes (PVDF: 5x, PE: 2x, Nanoparticle: 3x), custom high-throughput (HT) screening systems have been developed for their characterization. By coupling the data spaces obtained via these systems with the appropriate statistical and data analysis tools it was found that, despite not being directly involved in the proton transport process, the inert PVDF phase plays a major role on proton conductivity. Particularly, a univocal inverse correlation between the PVDF crystalline characteristics (i.e., crystallinity and crystallite size) and melt viscosity, and membrane proton conductivity was discovered. Membranes based on highly crystalline and viscous PVDF homopolymers exhibited reduced proton

Meals in orbit. [Space Shuttle food service planning

Science.gov (United States)

1980-01-01

Space foods which will be available to the Space Shuttle crew are discussed in view of the research and development of proper nutrition in space that began with the pastelike tube meals of the Mercury and Gemini astronauts. The variety of food types proposed for the Space Shuttle crew which include thermostabilized, intermediate moisture, rehydratable, irradiated, freeze-dried and natural forms are shown to be a result of the successive improvements in the Apollo, Skylab and Apollo Soyuz test project flights. The Space Shuttle crew will also benefit from an increase of caloric content (3,000 cal./day), the convenience of a real oven and a comfortable dining and kitchen area.

Baryon production in proton-proton collisions

International Nuclear Information System (INIS)

Liu, F.M.; Werner, K.

2002-01-01

Motivated by the recent rapidity spectra of baryons and antibaryons in pp collisions at 158 GeV and the Ω-bar/Ω ratio discussion, we reviewed string formation mechanism and some string models. This investigation told us how color strings are formed in ultrarelativistic proton-proton collisions

Quarkonium production in high energy proton-proton and proton-nucleus collisions

International Nuclear Information System (INIS)

Conesa del Valle, Z.; Corcella, G.; Fleuret, F.; Ferreiro, E.G.; Kartvelishvili, V.; Kopeliovich, B.; Lansberg, J.P.; Lourenco, C.; Martinez, G.; Papadimitriou, V.; Satz, H.; Scomparin, E.; Ullrich, T.; Teryaev, O.; Vogt, R.; Wang, J.X.

2011-01-01

We present a brief overview of the most relevant current issues related to quarkonium production in high energy proton-proton and proton-nucleus collisions along with some perspectives. After reviewing recent experimental and theoretical results on quarkonium production in pp and pA collisions, we discuss the emerging field of polarisation studies. Afterwards, we report on issues related to heavy-quark production, both in pp and pA collisions, complemented by AA collisions. To put the work in broader perpectives, we emphasize the need for new observables to investigate the quarkonium production mechanisms and reiterate the qualities that make quarkonia a unique tool for many investigations in particle and nuclear physics.

Holography on the NASA Space Shuttle

Science.gov (United States)

Wuerker, R. F.; Heflinger, L. O.; Flannery, J. V.; Kassel, A.; Rollauer, A. M.

1980-01-01

The SL-3 flight on the Space Shuttle will carry a 25 mW He-Ne laser holographic recorder for recording the solution growth of triglycine sulfate (TGS) crystals under low-zero gravity conditions. Three hundred holograms (two orthogonal views) will be taken (on SO-253 film) of each growth experiment. Processing and analysis (i.e., reconstructed imagery, holographic schlieren, reverse reference beam microscopy, and stored beam interferometry) of the holographic records will be done at NASA/MSFC. Other uses of the recorder on the Shuttle have been proposed.

The use of the Space Shuttle for land remote sensing

Science.gov (United States)

Thome, P. G.

1982-01-01

The use of the Space Shuttle for land remote sensing will grow significantly during the 1980's. The main use will be for general land cover and geological mapping purposes by worldwide users employing specialized sensors such as: high resolution film systems, synthetic aperture radars, and multispectral visible/IR electronic linear array scanners. Because these type sensors have low Space Shuttle load factors, the user's preference will be for shared flights. With this strong preference and given the present prognosis for Space Shuttle flight frequency as a function of orbit inclination, the strongest demand will be for 57 deg orbits. However, significant use will be made of lower inclination orbits. Compared with freeflying satellites, Space Shuttle mission investment requirements will be significantly lower. The use of the Space Shuttle for testing R and D land remote sensors will replace the free-flying satellites for most test programs.

Use of Probabilistic Risk Assessment in Shuttle Decision Making Process

Science.gov (United States)

Boyer, Roger L.; Hamlin, Teri, L.

2011-01-01

This slide presentation reviews the use of Probabilistic Risk Assessment (PRA) to assist in the decision making for the shuttle design and operation. Probabilistic Risk Assessment (PRA) is a comprehensive, structured, and disciplined approach to identifying and analyzing risk in complex systems and/or processes that seeks answers to three basic questions: (i.e., what can go wrong? what is the likelihood of these occurring? and what are the consequences that could result if these occur?) The purpose of the Shuttle PRA (SPRA) is to provide a useful risk management tool for the Space Shuttle Program (SSP) to identify strengths and possible weaknesses in the Shuttle design and operation. SPRA was initially developed to support upgrade decisions, but has evolved into a tool that supports Flight Readiness Reviews (FRR) and near real-time flight decisions. Examples of the use of PRA for the shuttle are reviewed.

A Sustainable, Reliable Mission-Systems Architecture that Supports a System of Systems Approach to Space Exploration

Science.gov (United States)

Watson, Steve; Orr, Jim; O'Neil, Graham

2004-01-01

A mission-systems architecture based on a highly modular "systems of systems" infrastructure utilizing open-standards hardware and software interfaces as the enabling technology is absolutely essential for an affordable and sustainable space exploration program. This architecture requires (a) robust communication between heterogeneous systems, (b) high reliability, (c) minimal mission-to-mission reconfiguration, (d) affordable development, system integration, and verification of systems, and (e) minimum sustaining engineering. This paper proposes such an architecture. Lessons learned from the space shuttle program are applied to help define and refine the model.

The underlying event in proton-proton collisions

Energy Technology Data Exchange (ETDEWEB)

Bechtel, F.

2009-05-15

In this thesis, studies of the underlying event in proton-proton collisions at a center-of-mass energy of {radical}(s) = 10 TeV are presented. Crucial ingredient to underlying event models are multiple parton-parton scatters in single proton-proton collisions. The feasibility of measuring the underlying event was investigated with the Compact Muon Solenoid (CMS) detector at the Large Hadron Collider (LHC) using charged particles and charged-particle jets. Systematic uncertainties of the underlying event measurement due to detector misalignment and imperfect track reconstruction are found to be negligible after {integral}Ldt=1 pb{sup -1} of data are available. Different model predictions are compared with each other using fully simulated Monte Carlo samples. It is found, that distinct models differ strongly enough to tell them apart with early data. (orig.)

Space Shuttle GN and C Development History and Evolution

Science.gov (United States)

Zimpfer, Douglas; Hattis, Phil; Ruppert, John; Gavert, Don

2011-01-01

Completion of the final Space Shuttle flight marks the end of a significant era in Human Spaceflight. Developed in the 1970 s, first launched in 1981, the Space Shuttle embodies many significant engineering achievements. One of these is the development and operation of the first extensive fly-by-wire human space transportation Guidance, Navigation and Control (GN&C) System. Development of the Space Shuttle GN&C represented first time inclusions of modern techniques for electronics, software, algorithms, systems and management in a complex system. Numerous technical design trades and lessons learned continue to drive current vehicle development. For example, the Space Shuttle GN&C system incorporated redundant systems, complex algorithms and flight software rigorously verified through integrated vehicle simulations and avionics integration testing techniques. Over the past thirty years, the Shuttle GN&C continued to go through a series of upgrades to improve safety, performance and to enable the complex flight operations required for assembly of the international space station. Upgrades to the GN&C ranged from the addition of nose wheel steering to modifications that extend capabilities to control of the large flexible configurations while being docked to the Space Station. This paper provides a history of the development and evolution of the Space Shuttle GN&C system. Emphasis is placed on key architecture decisions, design trades and the lessons learned for future complex space transportation system developments. Finally, some of the interesting flight operations experience is provided to inform future developers of flight experiences.

MUSE: Measuring the proton radius with muon-proton scattering

Energy Technology Data Exchange (ETDEWEB)

Bernauer, Jan Christopher [Massachusetts Institute of Technology, Cambridge (United States)

2014-07-01

The proton radius has been measured so far using electron-proton scattering, electronic Hydrogen spectroscopy and muonic Hydrogen spectroscopy, the latter producing a much more accurate, but seven sigma different, result, leading to the now famous proton radius puzzle. The MUSE collaboration aims to complete the set of measurements by using muon scattering to determine the proton radius and to shed light on possible explanations of the discrepancy. The talk gives an overview of the experiment motivation and design and a status report on the progress.

Proton therapy device

International Nuclear Information System (INIS)

Tronc, D.

1994-01-01

The invention concerns a proton therapy device using a proton linear accelerator which produces a proton beam with high energies and intensities. The invention lies in actual fact that the proton beam which is produced by the linear accelerator is deflected from 270 deg in its plan by a deflecting magnetic device towards a patient support including a bed the longitudinal axis of which is parallel to the proton beam leaving the linear accelerator. The patient support and the deflecting device turn together around the proton beam axis while the bed stays in an horizontal position. The invention applies to radiotherapy. 6 refs., 5 figs

A Dynamic Risk Model for Evaluation of Space Shuttle Abort Scenarios

Science.gov (United States)

Henderson, Edward M.; Maggio, Gaspare; Elrada, Hassan A.; Yazdpour, Sabrina J.

2003-01-01

The Space Shuttle is an advanced manned launch system with a respectable history of service and a demonstrated level of safety. Recent studies have shown that the Space Shuttle has a relatively low probability of having a failure that is instantaneously catastrophic during nominal flight as compared with many US and international launch systems. However, since the Space Shuttle is a manned. system, a number of mission abort contingencies exist to primarily ensure the safety of the crew during off-nominal situations and to attempt to maintain the integrity of the Orbiter. As the Space Shuttle ascends to orbit it transverses various intact abort regions evaluated and planned before the flight to ensure that the Space Shuttle Orbiter, along with its crew, may be returned intact either to the original launch site, a transoceanic landing site, or returned from a substandard orbit. An intact abort may be initiated due to a number of system failures but the highest likelihood and most challenging abort scenarios are initiated by a premature shutdown of a Space Shuttle Main Engine (SSME). The potential consequences of such a shutdown vary as a function of a number of mission parameters but all of them may be related to mission time for a specific mission profile. This paper focuses on the Dynamic Abort Risk Evaluation (DARE) model process, applications, and its capability to evaluate the risk of Loss Of Vehicle (LOV) due to the complex systems interactions that occur during Space Shuttle intact abort scenarios. In addition, the paper will examine which of the Space Shuttle subsystems are critical to ensuring a successful return of the Space Shuttle Orbiter and crew from such a situation.

Proton relays in anomalous carbocations dictate spectroscopy, stability, and mechanisms: case studies on C2H5+ and C3H3.

Science.gov (United States)

Sager, LeeAnn M; Iyengar, Srinivasan S

2017-10-18

We present a detailed analysis of the anomalous carbocations: C 2 H 5 + and C 3 H 3 + . This work involves (a) probing electronic structural properties, (b) ab initio dynamics simulations over a range of internal energies, (c) analysis of reduced dimensional potential surfaces directed along selected conformational transition pathways, (d) dynamically averaged vibrational spectra computed from ab initio dynamics trajectories, and (e) two-dimensional time-frequency analysis to probe conformational dynamics. Key findings are as follows: (i) as noted in our previous study on C 2 H 3 + , it appears that these non-classical carbocations are stabilized by delocalized nuclear frameworks and "proton shuttles". We analyze this nuclear delocalization and find critical parallels between conformational changes in C 2 H 3 + , C 2 H 5 + , and C 3 H 3 + . (ii) The vibrational signatures of C 2 H 5 + are dominated by the "bridge-proton" conformation, but also show critical contributions from the "classical" configuration, which is a transition state at almost all levels of theory. This result is further substantiated through two-dimensional time-frequency analysis and is at odds with earlier explanations of the experimental spectra, where frequencies close to the classical region were thought to arise from an impurity. While this is still possible, our results here indicate an additional (perhaps more likely) explanation that involves the "classical" isomer. (iii) Finally, in the case of C 3 H 3 + our explanation of the experimental result includes the presence of multiple, namely, "cyclic", "straight", and propargyl, configurations. Proton shuttles and nuclear delocalization, reminiscent of those seen in the case of C 2 H 3 + , were seen all through and have a critical role in all our observations.

Delayed protons and properties of proton-rich nuclei

International Nuclear Information System (INIS)

Karnaukhov, V.A.

1976-01-01

The object of the investigation is to study the properties of proton-rich nuclei. The emphasis in the proposed survey is made on investigations in the range of Z > 50. Measurement of the total energy in emission of delayed protons (DP) enables one to determine the difference between the masses of initial and final isotopes. The statistical model of the DP emission is used for describing the proton spectrum. A comparison of the DP experimental and theoretical spectra shows that the presence of local resonances in the strength functions of the β dacay is rather a rule than an exception. Studies into the fine structure of the proton spectra supply information of the density of nuclei considerably removed from the β-stability line at the excitation energies of 3-7 MeV. The aproaches for retrieval of nuclear information with the aid of proton radiators developed so far can serve as a good basis for systematic investigation over a wide range of A and Z

Space shuttle program: Shuttle Avionics Integration Laboratory. Volume 7: Logistics management plan

Science.gov (United States)

1974-01-01

The logistics management plan for the shuttle avionics integration laboratory defines the organization, disciplines, and methodology for managing and controlling logistics support. Those elements requiring management include maintainability and reliability, maintenance planning, support and test equipment, supply support, transportation and handling, technical data, facilities, personnel and training, funding, and management data.

Predictions of diffractive cross sections in proton-proton collisions

Energy Technology Data Exchange (ETDEWEB)

Goulianos, Konstantin [Rockefeller University, 1230 York Avenue, New York, NY 10065 (United States)

2013-04-15

We review our pre-LHC predictions of the total, elastic, total-inelastic, and diffractive components of proton-proton cross sections at high energies, expressed in the form of unitarized expressions based on a special parton-model approach to diffraction employing inclusive proton parton distribution functions and QCD color factors and compare with recent LHC results.

Spherical proton emitters

International Nuclear Information System (INIS)

Berg, S.; Semmes, P.B.; Nazarewicz, W.

1997-01-01

Various theoretical approaches to proton emission from spherical nuclei are investigated, and it is found that all the methods employed give very similar results. The calculated decay widths are found to be qualitatively insensitive to the parameters of the proton-nucleus potential, i.e., changing the potential parameters over a fairly large range typically changes the decay width by no more than a factor of ∼3. Proton half-lives of observed heavy proton emitters are, in general, well reproduced by spherical calculations with the spectroscopic factors calculated in the independent quasiparticle approximation. The quantitative agreement with experimental data obtained in our study requires that the parameters of the proton-nucleus potential be chosen carefully. It also suggests that deformed proton emitters will provide invaluable spectroscopic information on the angular momentum decomposition of single-proton orbitals in deformed nuclei. copyright 1997 The American Physical Society

Proton therapy physics

CERN Document Server

2012-01-01

Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also exami...

Proceedings of the Space Shuttle Environmental Assessment Workshop on Stratospheric Effects

Science.gov (United States)

Potter, A. E. (Compiler)

1977-01-01

Various aspects of the potential environmental impact of space shuttle exhaust are explored. Topics include: (1) increased ultraviolet radiation levels in the biosphere due to destruction of atmospheric ozone; (2) climatic changes due to aerosol particles affecting the planetary albedo; (3) space shuttle propellants (including alternate formulations); and (4) measurement of space shuttle exhaust products.

Synchronizing a single-electron shuttle to an external drive

Science.gov (United States)

Moeckel, Michael J.; Southworth, Darren R.; Weig, Eva M.; Marquardt, Florian

2014-04-01

The nanomechanical single-electron shuttle is a resonant system in which a suspended metallic island oscillates between and impacts at two electrodes. This setup holds promise for one-by-one electron transport and the establishment of an absolute current standard. While the charge transported per oscillation by the nanoscale island will be quantized in the Coulomb blockade regime, the frequency of such a shuttle depends sensitively on many parameters, leading to drift and noise. Instead of considering the nonlinearities introduced by the impact events as a nuisance, here we propose to exploit the resulting nonlinear dynamics to realize a highly precise oscillation frequency via synchronization of the shuttle self-oscillations to an external signal. We link the established phenomenological description of synchronization based on the Adler equation to the microscopic nonlinear dynamics of the electron shuttle by calculating the effective Adler constant analytically in terms of the microscopic parameters.

Synchronizing a single-electron shuttle to an external drive

International Nuclear Information System (INIS)

Moeckel, Michael J; Southworth, Darren R; Weig, Eva M; Marquardt, Florian

2014-01-01

The nanomechanical single-electron shuttle is a resonant system in which a suspended metallic island oscillates between and impacts at two electrodes. This setup holds promise for one-by-one electron transport and the establishment of an absolute current standard. While the charge transported per oscillation by the nanoscale island will be quantized in the Coulomb blockade regime, the frequency of such a shuttle depends sensitively on many parameters, leading to drift and noise. Instead of considering the nonlinearities introduced by the impact events as a nuisance, here we propose to exploit the resulting nonlinear dynamics to realize a highly precise oscillation frequency via synchronization of the shuttle self-oscillations to an external signal. We link the established phenomenological description of synchronization based on the Adler equation to the microscopic nonlinear dynamics of the electron shuttle by calculating the effective Adler constant analytically in terms of the microscopic parameters

Aboard the Space Shuttle.

Science.gov (United States)

Steinberg, Florence S.

This 32-page pamphlet contains color photographs and detailed diagrams which illustrate general descriptive comments about living conditions aboard the space shuttle. Described are details of the launch, the cabin, the condition of weightlessness, food, sleep, exercise, atmosphere, personal hygiene, medicine, going EVA (extra-vehicular activity),…

Mobile Christian - shuttle flight

Science.gov (United States)

2009-01-01

Erin Whittle, 14, (seated) and Brianna Johnson, 14, look on as Louis Stork, 13, attempts a simulated landing of a space shuttle at StenniSphere. The young people were part of a group from Mobile Christian School in Mobile, Ala., that visited StenniSphere on April 21.

Elastic proton-proton scattering at RHIC

Energy Technology Data Exchange (ETDEWEB)

Yip, K.

2011-09-03

Here we describe elastic proton+proton (p+p) scattering measurements at RHIC in p+p collisions with a special optics run of {beta}* {approx} 21 m at STAR, at the center-of-mass energy {radical}s = 200 GeV during the last week of the RHIC 2009 run. We present preliminary results of single and double spin asymmetries.

A CGC/saturation approach for angular correlations in proton-proton scattering

Energy Technology Data Exchange (ETDEWEB)

Gotsman, E. [Tel Aviv University, Department of Particle Physics, School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Science, Tel Aviv (Israel); Levin, E. [Tel Aviv University, Department of Particle Physics, School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Science, Tel Aviv (Israel); Universidad Tecnica Federico Santa Maria, Departamento de Fisica, Valparaiso (Chile); Centro Cientifico-Tecnologico de Valparaiso, Valparaiso (Chile); Potashnikova, I. [Universidad Tecnica Federico Santa Maria, Departamento de Fisica, Valparaiso (Chile); Centro Cientifico-Tecnologico de Valparaiso, Valparaiso (Chile)

2017-09-15

We generalized our model for the description of hard processes, and calculate the value of the azimuthal angular correlations (Fourier harmonics v{sub n}), for proton-proton scattering. The energy and multiplicity independence, as well as the value of v{sub n}, turns out to be in accord with the experimental data, or slightly larger. Therefore, before making extreme assumptions on proton-proton collisions, such as the production of a quark-gluon plasma in large multiplicity events, we need to understand how these affect the Bose-Einstein correlations, which have to be taken into account since the Bose-Einstein correlations are able to describe the angular correlations in proton-proton collisions, without including final state interactions. (orig.)

Proton-proton elastic scattering measurements at COSY

Energy Technology Data Exchange (ETDEWEB)

Bagdasarian, Zara [Forschungszentrum Juelich, Juelich (Germany); Tbilisi State University, Tbilisi (Georgia); Collaboration: ANKE-Collaboration

2014-07-01

To construct the reliable phase shift analysis (PSA) that can successfully describe the nucleon-nucleon (NN) interaction it is necessary to measure variety of experimental observables for both proton-proton (pp) and neutron-proton (np) elastic scattering. The polarized beams and targets at COSY-ANKE facility allow a substantial contribution to the existing database. The experiment was carried out in April 2013 at ANKE using a transversely polarized proton beam incident on an unpolarized hydrogen cluster target. Six beam energies of T{sub p}=0.8,1.6,1.8,2.0,2.2,2.4 GeV were used. The aim of this talk is to present the preliminary results for the analyzing power (A{sub y}) for the pp elastic scattering in the so-far unexplored 5 <θ{sub cm}<30 angular range. Our measurements are also compared to the world data and current partial wave solutions.

Correlations associated with small angle protons produced in proton- proton collisions at 31 GeV total energy

CERN Document Server

Albrow, M G; Barber, D P; Bogaerts, A; Bosnjakovic, B; Brooks, J R; Clegg, A B; Erné, F C; Gee, C N P; Locke, D H; Loebinger, F K; Murphy, P G; Rudge, A; Sens, Johannes C

1973-01-01

High energy inelastic protons with x=2 p/sub L//s/sup 1/2/>0.99 observed in 15.3/15.3 GeV proton-proton collisions at the CERN ISR are accompanied by particles whose angular distribution is confined to a narrow cone in the opposite direction. In contrast, lower energy protons (0.72

Proton-proton reaction rates at extreme energies

International Nuclear Information System (INIS)

Nagano, Motohiko

1993-01-01

Results on proton-antiproton reaction rates (total cross-section) at collision energies of 1.8 TeV from experiments at Fermilab have suggested a lower rate of increase with energy compared to the extrapolation based on results previously obtained at CERN's proton-antiproton collider (CERN Courier, October 1991). Now an independent estimate of the values for the proton-proton total cross-section for collision energies from 5 to 30 TeV has been provided by the analysis of cosmic ray shower data collected over ten years at the Akeno Observatory operated by the Institute for Cosmic Ray Research of University of Tokyo. These results are based on the inelastic cross-section for collisions of cosmic ray protons with air nuclei at energies in the range10 16-18 eV. A new extensive air shower experiment was started at Akeno, 150 km west of Tokyo, in 1979 with a large array of detectors, both on the ground and under a 1-metre concrete absorber. This measured the total numbers of electrons and muons of energies above 1GeV for individual showers with much better accuracy than before. Data collection was almost continuous for ten years without any change in the triggering criteria for showers above10 16 eV. The mean free path for proton-air nuclei collisions has been determined from the zenith angle of the observed frequency of air showers which have the same effective path length for development in the atmosphere and the same primary energy

Directional control-response compatibility of joystick steered shuttle cars.

Science.gov (United States)

Burgess-Limerick, Robin; Zupanc, Christine M; Wallis, Guy

2012-01-01

Shuttle cars are an unusual class of vehicle operated in underground coal mines, sometimes in close proximity to pedestrians and steering errors may have very serious consequences. A directional control-response incompatibility has previously been described in shuttle cars which are controlled using a steering wheel oriented perpendicular to the direction of travel. Some other shuttle car operators are seated perpendicular to the direction of travel and steer the car via a seat mounted joystick. A virtual simulation was utilised to determine whether the steering arrangement in these vehicles maintains directional control-response compatibility. Twenty-four participants were randomly assigned to either a condition corresponding to this design (consistent direction), or a condition in which the directional steering response was reversed while driving in-bye (visual field compatible). Significantly less accurate steering performance was exhibited by the consistent direction group during the in-bye trials only. Shuttle cars which provide the joystick steering mechanism described here require operators to accommodate alternating compatible and incompatible directional control-response relationships with each change of car direction. A virtual simulation of an underground coal shuttle car demonstrates that the design incorporates a directional control-response incompatibility when driving the vehicle in one direction. This design increases the probability of operator error, with potential adverse safety and productivity consequences.

Study of proton radioactivities

Energy Technology Data Exchange (ETDEWEB)

Davids, C.N.; Back, B.B.; Henderson, D.J. [and others

1995-08-01

About a dozen nuclei are currently known to accomplish their radioactive decay by emitting a proton. These nuclei are situated far from the valley of stability, and mark the very limits of existence for proton-rich nuclei: the proton drip line. A new 39-ms proton radioactivity was observed following the bombardment of a {sup 96}Ru target by a beam of 420-MeV {sup 78}Kr. Using the double-sided Si strip detector implantation system at the FMA, a proton group having an energy of 1.05 MeV was observed, correlated with the implantation of ions having mass 167. The subsequent daughter decay was identified as {sup 166}Os by its characteristic alpha decay, and therefore the proton emitter is assigned to the {sup 167}Ir nucleus. Further analysis showed that a second weak proton group from the same nucleus is present, indicating an isomeric state. Two other proton emitters were discovered recently at the FMA: {sup 171}Au and {sup 185}Bi, which is the heaviest known proton radioactivity. The measured decay energies and half-lives will enable the angular momentum of the emitted protons to be determined, thus providing spectroscopic information on nuclei that are beyond the proton drip line. In addition, the decay energy yields the mass of the nucleus, providing a sensitive test of mass models in this extremely proton-rich region of the chart of the nuclides. Additional searches for proton emitters will be conducted in the future, in order to extend our knowledge of the location of the proton drip line.

Space Shuttle Orbiter Endeavour STS-47 Launch

Science.gov (United States)

1992-01-01

A smooth countdown culminated in a picture-perfect launch as the Space Shuttle Orbiter Endeavour (STS-47) climbed skyward atop a ladder of billowing smoke on September 12, 1992. The primary payload for the plarned seven-day flight was the Spacelab-J science laboratory. The second flight of Endeavour marks a number of historic firsts: the first space flight of an African-American woman, the first Japanese citizen to fly on a Space Shuttle, and the first married couple to fly in space.

Parametric Model for Astrophysical Proton-Proton Interactions and Applications

Energy Technology Data Exchange (ETDEWEB)

Karlsson, Niklas [KTH Royal Institute of Technology, Stockholm (Sweden)

2007-01-01

Observations of gamma-rays have been made from celestial sources such as active galaxies, gamma-ray bursts and supernova remnants as well as the Galactic ridge. The study of gamma rays can provide information about production mechanisms and cosmic-ray acceleration. In the high-energy regime, one of the dominant mechanisms for gamma-ray production is the decay of neutral pions produced in interactions of ultra-relativistic cosmic-ray nuclei and interstellar matter. Presented here is a parametric model for calculations of inclusive cross sections and transverse momentum distributions for secondary particles--gamma rays, e^±, v_e, $\\bar{v}$_e, v_μ and $\\bar{μ}$_e--produced in proton-proton interactions. This parametric model is derived on the proton-proton interaction model proposed by Kamae et al.; it includes the diffraction dissociation process, Feynman-scaling violation and the logarithmically rising inelastic proton-proton cross section. To improve fidelity to experimental data for lower energies, two baryon resonance excitation processes were added; one representing the Δ(1232) and the other multiple resonances with masses around 1600 MeV/c². The model predicts the power-law spectral index for all secondary particle to be about 0.05 lower in absolute value than that of the incident proton and their inclusive cross sections to be larger than those predicted by previous models based on the Feynman-scaling hypothesis. The applications of the presented model in astrophysics are plentiful. It has been implemented into the Galprop code to calculate the contribution due to pion decays in the Galactic plane. The model has also been used to estimate the cosmic-ray flux in the Large Magellanic Cloud based on HI, CO and gamma-ray observations. The transverse momentum distributions enable calculations when the proton distribution is anisotropic. It is shown that the gamma-ray spectrum and flux due to a

Search for Sphalerons in Proton-Proton Collisions

CERN Document Server

Ellis, John

2016-04-14

In a recent paper, Tye and Wong (TW) have argued that sphaleron-induced transitions in high-energy proton-proton collisions should be enhanced compared to previous calculations, based on a construction of a Bloch wave function in the periodic sphaleron potential and the corresponding pass band structure. Here we convolute the calculations of TW with parton distribution functions and simulations of final states to explore the signatures of sphaleron transitions at the LHC and possible future colliders. We calculate the increase of sphaleron transition rates in proton-proton collisions at centre-of-mass energies of 13/14/33/100 TeV for different sphaleron barrier heights, while recognising that the rates have large overall uncertainties. We use a simulation to show that LHC searches for microscopic black holes should have good efficiency for detecting sphaleron-induced final states, and discuss their experimental signatures and observability in Run 2 of the LHC and beyond. We recast the early ATLAS Run-2 search...

From 2D to 3D: Proton Radiography and Proton CT in proton therapy: A simulation study

NARCIS (Netherlands)

Takatsu, J.; van der Graaf, E.R.; van Goethem, M.-J.; Brandenburg, S.; Biegun, Aleksandra

(1) Purpose In order to reduce the uncertainty in translation of the X-ray Computed Tomography (CT) image into a map of proton stopping powers (3-4% and even up to 10% in regions containing bones [1-8]), proton radiography is being studied as an alternative imaging technique in proton therapy. We

Vibrational spectroscopy on protons and deuterons in proton conducting perovskites

DEFF Research Database (Denmark)

Glerup, M.; Poulsen, F.W.; Berg, R.W.

2002-01-01

A short review of IR-spectroscopy on protons in perovskite structure oxides is given. The nature of possible proton sites, libration and combination tones and degree of hydrogen bonding is emphasised. Three new spectroscopic experiments and/or interpretations are presented. An IR-microscopy exper......A short review of IR-spectroscopy on protons in perovskite structure oxides is given. The nature of possible proton sites, libration and combination tones and degree of hydrogen bonding is emphasised. Three new spectroscopic experiments and/or interpretations are presented. An IR...

Inhibition of hepatitis B virus replication with linear DNA sequences expressing antiviral micro-RNA shuttles

Energy Technology Data Exchange (ETDEWEB)

Chattopadhyay, Saket; Ely, Abdullah; Bloom, Kristie; Weinberg, Marc S. [Antiviral Gene Therapy Research Unit, University of the Witwatersrand (South Africa); Arbuthnot, Patrick, E-mail: Patrick.Arbuthnot@wits.ac.za [Antiviral Gene Therapy Research Unit, University of the Witwatersrand (South Africa)

2009-11-20

RNA interference (RNAi) may be harnessed to inhibit viral gene expression and this approach is being developed to counter chronic infection with hepatitis B virus (HBV). Compared to synthetic RNAi activators, DNA expression cassettes that generate silencing sequences have advantages of sustained efficacy and ease of propagation in plasmid DNA (pDNA). However, the large size of pDNAs and inclusion of sequences conferring antibiotic resistance and immunostimulation limit delivery efficiency and safety. To develop use of alternative DNA templates that may be applied for therapeutic gene silencing, we assessed the usefulness of PCR-generated linear expression cassettes that produce anti-HBV micro-RNA (miR) shuttles. We found that silencing of HBV markers of replication was efficient (>75%) in cell culture and in vivo. miR shuttles were processed to form anti-HBV guide strands and there was no evidence of induction of the interferon response. Modification of terminal sequences to include flanking human adenoviral type-5 inverted terminal repeats was easily achieved and did not compromise silencing efficacy. These linear DNA sequences should have utility in the development of gene silencing applications where modifications of terminal elements with elimination of potentially harmful and non-essential sequences are required.

Inhibition of hepatitis B virus replication with linear DNA sequences expressing antiviral micro-RNA shuttles

International Nuclear Information System (INIS)

Chattopadhyay, Saket; Ely, Abdullah; Bloom, Kristie; Weinberg, Marc S.; Arbuthnot, Patrick

2009-01-01

RNA interference (RNAi) may be harnessed to inhibit viral gene expression and this approach is being developed to counter chronic infection with hepatitis B virus (HBV). Compared to synthetic RNAi activators, DNA expression cassettes that generate silencing sequences have advantages of sustained efficacy and ease of propagation in plasmid DNA (pDNA). However, the large size of pDNAs and inclusion of sequences conferring antibiotic resistance and immunostimulation limit delivery efficiency and safety. To develop use of alternative DNA templates that may be applied for therapeutic gene silencing, we assessed the usefulness of PCR-generated linear expression cassettes that produce anti-HBV micro-RNA (miR) shuttles. We found that silencing of HBV markers of replication was efficient (>75%) in cell culture and in vivo. miR shuttles were processed to form anti-HBV guide strands and there was no evidence of induction of the interferon response. Modification of terminal sequences to include flanking human adenoviral type-5 inverted terminal repeats was easily achieved and did not compromise silencing efficacy. These linear DNA sequences should have utility in the development of gene silencing applications where modifications of terminal elements with elimination of potentially harmful and non-essential sequences are required.

'Secret' Shuttle payloads revealed

Science.gov (United States)

Powell, Joel W.

1993-05-01

A secret military payload carried by the orbiter Discovery launched on January 24 1985 is discussed. Secondary payloads on the military Shuttle flights are briefly reviewed. Most of the military middeck experiments were sponsored by the Space Test Program established at the Pentagon to oversee all Defense Department space research projects.

Steam electrolysis by solid oxide electrolysis cells (SOECs) with proton-conducting oxides

KAUST Repository

Bi, Lei; Boulfrad, Samir; Traversa, Enrico

2014-01-01

Energy crisis and environmental problems caused by the conventional combustion of fossil fuels boost the development of renewable and sustainable energies. H2 is regarded as a clean fuel for many applications and it also serves as an energy carrier for many renewable energy sources, such as solar and wind power. Among all the technologies for H2 production, steam electrolysis by solid oxide electrolysis cells (SOECs) has attracted much attention due to its high efficiency and low environmental impact, provided that the needed electrical power is generated from renewable sources. However, the deployment of SOECs based on conventional oxygen-ion conductors is limited by several issues, such as high operating temperature, hydrogen purification from water, and electrode stability. To avoid these problems, proton-conducting oxides are proposed as electrolyte materials for SOECs. This review paper provides a broad overview of the research progresses made for proton-conducting SOECs, summarizing the past work and finding the problems for the development of proton-conducting SOECs, as well as pointing out potential development directions.

Steam electrolysis by solid oxide electrolysis cells (SOECs) with proton-conducting oxides.

Science.gov (United States)

Bi, Lei; Boulfrad, Samir; Traversa, Enrico

2014-12-21

Energy crisis and environmental problems caused by the conventional combustion of fossil fuels boost the development of renewable and sustainable energies. H2 is regarded as a clean fuel for many applications and it also serves as an energy carrier for many renewable energy sources, such as solar and wind power. Among all the technologies for H2 production, steam electrolysis by solid oxide electrolysis cells (SOECs) has attracted much attention due to its high efficiency and low environmental impact, provided that the needed electrical power is generated from renewable sources. However, the deployment of SOECs based on conventional oxygen-ion conductors is limited by several issues, such as high operating temperature, hydrogen purification from water, and electrode stability. To avoid these problems, proton-conducting oxides are proposed as electrolyte materials for SOECs. This review paper provides a broad overview of the research progresses made for proton-conducting SOECs, summarizing the past work and finding the problems for the development of proton-conducting SOECs, as well as pointing out potential development directions.

Redox shuttles for overcharge protection of lithium batteries

Science.gov (United States)

Amine, Khalil; Chen, Zonghai; Wang, Qingzheng

2010-12-14

The present invention is generally related to electrolytes containing novel redox shuttles for overcharge protection of lithium-ion batteries. The redox shuttles are capable of thousands hours of overcharge tolerance and have a redox potential at about 3-5.5 V vs. Li and particularly about 4.4-4.8 V vs. Li. Accordingly, in one aspect the invention provides electrolytes comprising an alkali metal salt; a polar aprotic solvent; and a redox shuttle additive that is an aromatic compound having at least one aromatic ring with four or more electronegative substituents, two or more oxygen atoms bonded to the aromatic ring, and no hydrogen atoms bonded to the aromatic ring; and wherein the electrolyte solution is substantially non-aqueous. Further there are provided electrochemical devices employing the electrolyte and methods of making the electrolyte.

NASA Shuttle Logistics Depot (NSLD) - The application of ATE

Science.gov (United States)

Simpkins, Lorenz G.; Jenkins, Henry C.; Mauceri, A. Jack

1990-01-01

The concept of the NASA Shuttle Logistics Depot (NSLD) developed for the Space Shuttle Orbiter Program is described. The function of the NSLD at Cape Canaveral is to perform the acceptance and diagnostic testing of the Shuttle's space-rated line-replaceable units and shop-replaceable units (SRUs). The NSLD includes a comprehensive electronic automatic test station, program development stations, and assorted manufacturing support equipment (including thermal and vibration test equipment, special test equipment, and a card SRU test system). The depot activities also include the establishment of the functions for manufacturing of mechanical parts, soldering, welding, painting, clean room operation, procurement, and subcontract management.

Ecological Impacts of the Space Shuttle Program at John F. Kennedy Space Center, Florida

Science.gov (United States)

Hall, Carlton R.; Schmalzer, Paul A.; Breininger, David R.; Duncan, Brean W.; Drese, John H.; Scheidt, Doug A.; Lowers, Russ H.; Reyier, Eric A.; Holloway-Adkins, Karen G.; Oddy, Donna M.;

Shuttle Planning for Link Closures in Urban Public Transport Networks

DEFF Research Database (Denmark)

van der Hurk, Evelien; Koutsopoulos, Haris N.; Wilson, Nigel

2016-01-01

Urban public transport systems must periodically close certain links for maintenance, which can have significant effects on the service provided to passengers. In practice, the effects of closures are mitigated by replacing the closed links with a simple shuttle service. However, alternative...... cost, which includes transfers and frequency-dependent waiting time costs. This model is applied to a shuttle design problem based on a real-world case study of the Massachusetts Bay Transportation Authority network of Boston, Massachusetts. The results show that additional shuttle routes can reduce...

Muscular soreness following prolonged intermittent high-intensity shuttle running.

Science.gov (United States)

Thompson, D; Nicholas, C W; Williams, C

1999-05-01

The aim of this study was to examine the impact of prolonged intermittent high-intensity shuttle running on soreness and markers of muscle damage. Sixteen males took part in the study, half of whom were assigned to a running group and half to a resting control group. The exercise protocol involved 90 min of intermittent shuttle running and walking (Loughborough Intermittent Shuttle Test: LIST), reflecting the activity pattern found in multiple-sprint sports such as soccer. Immediately after exercise, there was a significant increase (P < 0.05) in serum activities of creatine kinase and aspartate aminotransferase, and values remained above baseline for 48 h (P < 0.05). Median peak activities of creatine kinase and aspartate aminotransferase occurred 24 h post-exercise and were 774 and 43 U x l(-1), respectively. The intensity of general muscle soreness, and in the specific muscles investigated, was greater than baseline for 72 h after the shuttle test (P < 0.05), peaking 24-48 h post-exercise (P < 0.05). Muscle soreness was not correlated with either creatine kinase or aspartate aminotransferase activity. Soreness was most frequently reported in the hamstrings. Neither soreness nor serum enzyme activity changed in the controls over the 4 day observation period. It appears that unaccustomed performance of prolonged intermittent shuttle running produces a significant increase in both soreness and markers of muscle damage.

Review of inelastic proton-proton reactions

CERN Document Server

Morrison, Douglas Robert Ogston

1973-01-01

The most important new results on inelastic proton-proton scattering obtained with the new machines, I.S.R. and N.A.L., are: (1) The inelastic cross-section increases monotonically with energy from threshold to 1500 GeV/c. Above 6 GeV/c the energy variation has a s /sup +0.04/ behaviour. (2) Scaling is observed at I.S.R. energies in pion production. Confirmation is obtained of the hypothesis of limiting fragmentation. (3) The results are in general, consistent with the two-component model-one class of events being produced by diffraction dissociation and the other by a short-range-order process (e.g. the multiperipheral model). (4) There are indications that the protons have a granular structure; this from observation of secondaries of large transverse momenta. (33 refs).

Core characteristics on a hybrid type fast reactor system combined with proton accelerator

International Nuclear Information System (INIS)

Kowata, Yasuki; Otsubo, Akira

1997-06-01

In our study on a hybrid fast reactor system, we have investigated it from the view point of transmutation ability of trans-uranium (TRU) nuclide making the most effective use of special features (controllability, hard neutron spectrum) of the system. It is proved that a proton beam is superior in generation of neutrons compared with an electron beam. Therefore a proton accelerator using spallation reaction with a target nucleus has an advantage to transmutation of TRU than an electron one. A fast reactor is expected to primarily have a merit that the reactor can be operated for a long term without employment of highly enriched plutonium fuel by using external neutron source such as the proton accelerator. Namely, the system has a desirable characteristic of being possible to self-sustained fissile plutonium. Consequently in the present report, core characteristics of the system were roughly studied by analyses using 2D-BURN code. The possibility of self-sustained fuel was investigated from the burnup and neutronic calculation in a cylindrical core with 300w/cc of power density without considering a target material region for the accelerator. For a reference core of which the height and the radius are both 100 cm, there is a fair prospect that a long term reactor operation is possible with subsequent refueling of natural uranium, if the medium enriched (around 10wt%) uranium or plutonium fuels are fully loaded in the initial core. More precise analyses will be planed in a later fiscal year. (author)

A concise guide to sustainable PEMFCs: recent advances in improving both oxygen reduction catalysts and proton exchange membranes.

Science.gov (United States)

Scofield, Megan E; Liu, Haiqing; Wong, Stanislaus S

2015-08-21

The rising interest in fuel cell vehicle technology (FCV) has engendered a growing need and realization to develop rational chemical strategies to create highly efficient, durable, and cost-effective fuel cells. Specifically, technical limitations associated with the major constituent components of the basic proton exchange membrane fuel cell (PEMFC), namely the cathode catalyst and the proton exchange membrane (PEM), have proven to be particularly demanding to overcome. Therefore, research trends within the community in recent years have focused on (i) accelerating the sluggish kinetics of the catalyst at the cathode and (ii) minimizing overall Pt content, while simultaneously (a) maximizing activity and durability as well as (b) increasing membrane proton conductivity without causing any concomitant loss in either stability or as a result of damage due to flooding. In this light, as an example, high temperature PEMFCs offer a promising avenue to improve the overall efficiency and marketability of fuel cell technology. In this Critical Review, recent advances in optimizing both cathode materials and PEMs as well as the future and peculiar challenges associated with each of these systems will be discussed.

Electron Cloud Simulations of a Proton Storage Ring Using Cold Proton Bunches

International Nuclear Information System (INIS)

Sato, Y.; Holmes, Jeffrey A.; Lee, S.Y.; Macek, R.

2008-01-01

Using the ORBIT code we study the sensitivity of electron cloud properties with respect to different proton beam profiles, the secondary electron yield (SEY) parameter, and the proton loss rate. Our model uses a cold proton bunch to generate primary electrons and electromagnetic field for electron cloud dynamics. We study the dependence of the prompt and swept electron signals vs the bunch charge and the recovery of electron clouds after sweeping on the beam loss rate and the SEY. The simulation results are compared with the experimental data measured at the proton storage ring at the Los Alamos National Laboratory. Our simulations indicate that the fractional proton loss rate in the field-free straight section may be an exponential function of proton beam charge and may also be lower than the averaged fractional proton loss rate over the whole ring.

Study on the proton-induced X-ray emission(PIXE) using external proton beam

Energy Technology Data Exchange (ETDEWEB)

Yoon, M. Y.; Yoon, J. C.; Park, K. J. [Seoul Natioanl University, Seoul (Korea, Republic of)

2008-04-15

We intend to develop a system that can extract a proton beam into air for a qualitative, and quantitative PIXE analysis up to ppm(percent per million) composition. When such an R and D is accomplished, first it is possible to get equipped with a system for PIXE and PIGmE, second, it is possible to contribute to an academic progress by the study for physical properties of matter through an nuclear science methods when the comparison between the measurement and the calculated quantities, and third, it is possible to contribute to a multi-disciplinary researches by the measurements of the samples for which it is hard to get the SRM for the samples. We intend to develop methods to measure the beam current for an air-borne proton beam, and to minimize the energy and current loss of the beam. We intend to acquire a set of PIXE data for rare-earth metals and transient metals, to form a basic database for the analysis for various samples for which it is hard to get the SRM. Developed PIXE beamline can extract the beam diameter up to 5mm, and beam intensity in the range 0.5nA to 10nA variable. sustaining the vacuum better than 10{sup -6} mtorr. Necessary detection system and methodology are complete. As the application of the present research achievements, we studied the analysis of aerosol composition, the appraisal of the cultural heritages, and a feasibility study for a proton beam writing. It is expected to become possible to analyse the compositions of the gems, the elemental compositions of the food, the discrimination of the traditional ink and the modern ink on the documents, the evaluation of the documents by the analysis of the elemental composition of the stamps, The analysis of the paper with respect to the date and the quality, the analysis of the color, and the core bored samples

Current-current interaction picture for proton-proton scattering

International Nuclear Information System (INIS)

Clarke, D.J.; Lo, S.Y.

1979-01-01

The authors propose that color current - color current interaction is reponsible for small angle elastic proton proton scattering at asymptotic energy. Excellent fits are obtained for all data above 12 GeV/c which covers twelve orders of magnitude

A History of Space Shuttle Main Engine (SSME) Redline Limits Management

Science.gov (United States)

Arnold, Thomas M.

2011-01-01

The Space Shuttle Main Engine (SSME) has several "redlines", which are operational limits designated to preclude a catastrophic shutdown of the SSME. The Space Shuttle Orbiter utilizes a combination of hardware and software to enable or disable the automated redline shutdown capability. The Space Shuttle is launched with the automated SSME redline limits enabled, but there are many scenarios which may result in the manual disabling of the software by the onboard crew. The operational philosophy for manually enabling and disabling the redline limits software has evolved continuously throughout the history of the Space Shuttle Program, due to events such as SSME hardware changes and updates to Space Shuttle contingency abort software. In this paper, the evolution of SSME redline limits management will be fully reviewed, including the operational scenarios which call for manual intervention, and the events that triggered changes to the philosophy. Following this review, improvements to the management of redline limits for future spacecraft will be proposed.

Nanotechnology for environmentally sustainable electromobility

Science.gov (United States)

Ellingsen, Linda Ager-Wick; Hung, Christine Roxanne; Majeau-Bettez, Guillaume; Singh, Bhawna; Chen, Zhongwei; Whittingham, M. Stanley; Strømman, Anders Hammer

2016-12-01

Electric vehicles (EVs) powered by lithium-ion batteries (LIBs) or proton exchange membrane hydrogen fuel cells (PEMFCs) offer important potential climate change mitigation effects when combined with clean energy sources. The development of novel nanomaterials may bring about the next wave of technical improvements for LIBs and PEMFCs. If the next generation of EVs is to lead to not only reduced emissions during use but also environmentally sustainable production chains, the research on nanomaterials for LIBs and PEMFCs should be guided by a life-cycle perspective. In this Analysis, we describe an environmental life-cycle screening framework tailored to assess nanomaterials for electromobility. By applying this framework, we offer an early evaluation of the most promising nanomaterials for LIBs and PEMFCs and their potential contributions to the environmental sustainability of EV life cycles. Potential environmental trade-offs and gaps in nanomaterials research are identified to provide guidance for future nanomaterial developments for electromobility.

Surface proton transport of fully protonated poly(aspartic acid) thin films on quartz substrates

Energy Technology Data Exchange (ETDEWEB)

Nagao, Yuki, E-mail: ynagao@jaist.ac.jp; Kubo, Takahiro

2014-12-30

Graphical abstract: - Highlights: • Proton transport of fully protonated poly(aspartic acid) thin film was investigated. • The thin film structure differed greatly from the partially protonated one. • Proton transport occurs on the surface, not inside of the thin film. • This result contributes to biological transport systems such as bacteriorhodopsin. - Abstract: Thin film structure and the proton transport property of fully protonated poly(aspartic acid) (P-Asp100) have been investigated. An earlier study assessed partially protonated poly(aspartic acid), highly oriented thin film structure and enhancement of the internal proton transport. In this study of P-Asp100, IR p-polarized multiple-angle incidence resolution (P-MAIR) spectra were measured to investigate the thin film structure. The obtained thin films, with thicknesses of 120–670 nm, had no oriented structure. Relative humidity dependence of the resistance, proton conductivity, and normalized resistance were examined to ascertain the proton transport property of P-Asp100 thin films. The obtained data showed that the proton transport of P-Asp100 thin films might occur on the surface, not inside of the thin film. This phenomenon might be related with the proton transport of the biological system.

Surface proton transport of fully protonated poly(aspartic acid) thin films on quartz substrates

International Nuclear Information System (INIS)

Nagao, Yuki; Kubo, Takahiro

2014-01-01

Graphical abstract: - Highlights: • Proton transport of fully protonated poly(aspartic acid) thin film was investigated. • The thin film structure differed greatly from the partially protonated one. • Proton transport occurs on the surface, not inside of the thin film. • This result contributes to biological transport systems such as bacteriorhodopsin. - Abstract: Thin film structure and the proton transport property of fully protonated poly(aspartic acid) (P-Asp100) have been investigated. An earlier study assessed partially protonated poly(aspartic acid), highly oriented thin film structure and enhancement of the internal proton transport. In this study of P-Asp100, IR p-polarized multiple-angle incidence resolution (P-MAIR) spectra were measured to investigate the thin film structure. The obtained thin films, with thicknesses of 120–670 nm, had no oriented structure. Relative humidity dependence of the resistance, proton conductivity, and normalized resistance were examined to ascertain the proton transport property of P-Asp100 thin films. The obtained data showed that the proton transport of P-Asp100 thin films might occur on the surface, not inside of the thin film. This phenomenon might be related with the proton transport of the biological system

Proton-proton bremsstrahlung towards the elastic limit

Science.gov (United States)

Mahjour-Shafiei, M.; Amir-Ahmadi, H. R.; Bacelar, J. C. S.; Castelijns, R.; Ermisch, K.; van Garderen, E.; Gašparić, I.; Harakeh, M. N.; Kalantar-Nayestanaki, N.; Kiš, M.; Löhner, H.

2005-05-01

In oder to study proton-proton bremsstrahlung moving towards the elastic limit, a detection system, consisting of Plastic-ball and SALAD, was set up and an experiment at 190 MeV incident beam energy was performed. Here, the experimental setup and the data analysis procedure along with some results obtained in the measurement are discussed.

Proton-proton bremsstrahlung towards the elastic limit

International Nuclear Information System (INIS)

Mahjour-Shafiei, M.; Amir-Ahmadi, H.R.; Bacelar, J.C.S.; Castelijns, R.; Ermisch, K.; Garderen, E. van; Harakeh, M.N.; Kalantar-Nayestanaki, N.; Kis, M.; Loehner, H.; Gasparic, I.

2005-01-01

In oder to study proton-proton bremsstrahlung moving towards the elastic limit, a detection system, consisting of Plastic-ball and SALAD, was set up and an experiment at 190 MeV incident beam energy was performed. Here, the experimental setup and the data analysis procedure along with some results obtained in the measurement are discussed

Report of the Space Shuttle Management Independent Review Team

Science.gov (United States)

1995-02-01

At the request of the NASA Administrator a team was formed to review the Space Shuttle Program and propose a new management system that could significantly reduce operating costs. Composed of a group of people with broad and extensive experience in spaceflight and related areas, the team received briefings from the NASA organizations and most of the supporting contractors involved in the Shuttle Program. In addition, a number of chief executives from the supporting contractors provided advice and suggestions. The team found that the present management system has functioned reasonably well despite its diffuse structure. The team also determined that the shuttle has become a mature and reliable system, and--in terms of a manned rocket-propelled space launch system--is about as safe as today's technology will provide. In addition, NASA has reduced shuttle operating costs by about 25 percent over the past 3 years. The program, however, remains in a quasi-development mode and yearly costs remain higher than required. Given the current NASA-contractor structure and incentives, it is difficult to establish cost reduction as a primary goal and implement changes to achieve efficiencies. As a result, the team sought to create a management structure and associated environment that enables and motivates the Program to further reduce operational costs. Accordingly, the review team concluded that the NASA Space Shuttle Program should (1) establish a clear set of program goals, placing a greater emphasis on cost-efficient operations and user-friendly payload integration; (2) redefine the management structure, separating development and operations and disengaging NASA from the daily operation of the space shuttle; and (3) provide the necessary environment and conditions within the program to pursue these goals.

Shuttle Topography Data Inform Solar Power Analysis

Science.gov (United States)

2013-01-01

The next time you flip on a light switch, there s a chance that you could be benefitting from data originally acquired during the Space Shuttle Program. An effort spearheaded by Jet Propulsion Laboratory (JPL) and the National Geospatial-Intelligence Agency (NGA) in 2000 put together the first near-global elevation map of the Earth ever assembled, which has found use in everything from 3D terrain maps to models that inform solar power production. For the project, called the Shuttle Radar Topography Mission (SRTM), engineers at JPL designed a 60-meter mast that was fitted onto Shuttle Endeavour. Once deployed in space, an antenna attached to the end of the mast worked in combination with another antenna on the shuttle to simultaneously collect data from two perspectives. Just as having two eyes makes depth perception possible, the SRTM data sets could be combined to form an accurate picture of the Earth s surface elevations, the first hight-detail, near-global elevation map ever assembled. What made SRTM unique was not just its surface mapping capabilities but the completeness of the data it acquired. Over the course of 11 days, the shuttle orbited the Earth nearly 180 times, covering everything between the 60deg north and 54deg south latitudes, or roughly 80 percent of the world s total landmass. Of that targeted land area, 95 percent was mapped at least twice, and 24 percent was mapped at least four times. Following several years of processing, NASA released the data to the public in partnership with NGA. Robert Crippen, a member of the SRTM science team, says that the data have proven useful in a variety of fields. "Satellites have produced vast amounts of remote sensing data, which over the years have been mostly two-dimensional. But the Earth s surface is three-dimensional. Detailed topographic data give us the means to visualize and analyze remote sensing data in their natural three-dimensional structure, facilitating a greater understanding of the features

Proton-proton and deuteron-deuteron correlations in interactions of relativistic helium nuclei with protons

International Nuclear Information System (INIS)

Galazka-Friedman, J.; Sobczak, T.; Stepaniak, J.; Zielinski, I.P.; Bano, M.; Hlavacova, J.; Martinska, G.; Patocka, J.; Seman, M.; Sandor, L.; Urban, J.

1993-01-01

The reactions 4 Hep→pp+X, 3 Hep→pp+X and 4 Hep→ddp have been investigated and the correlation function has been measured for protons and deuterons with small relative momenta. Strong positive correlation has been observed for protons related mainly to the final state interactions in 1 S 0 state. The root mean square radius of the proton source calculated from the correlation function has been found to be equal to (1.7±0.3) fm and (2.1±0.3) fm for 4 He and 3 He respectively. It agrees with the known radii of these nuclei. (orig.)

Tracing the transition of a macro electron shuttle into nonlinear response

Energy Technology Data Exchange (ETDEWEB)

Kim, Chulki [Sensor System Research Center, Korea Institute of Science and Technology, Seoul 136791 (Korea, Republic of); Prada, Marta [I. Institut für Theoretische Physik, Universität Hamburg, Jungiusstr. 9, Hamburg 20355 (Germany); Qin, Hua [Key Laboratory of Nanodevices, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 398 Ruoshui Road, Industrial Park, Suzhou City, Jiangsu 215123 (China); Kim, Hyun-Seok [Division of Electronics and Electrical Engineering, Dongguk University-Seoul, 100715 Seoul (Korea, Republic of); Blick, Robert H., E-mail: rblick@physnet.uni-hamburg.de [Department of Physics, University of Wisconsin-Madison, 1150 University Avenue, Madison, Wisconsin-53706 (United States); Center for Hybrid Nanostructures, Universität Hamburg, Jungiusstr. 11c, Hamburg 20355 (Germany); Department of Electrical and Computer Engineering, University of Wisconsin-Madison, 1415 Engineering Dr. Madison, Wisconsin-53706 (United States)

2015-02-09

We present a study on a macroscopic electron shuttle in the transition from linear to nonlinear response. The shuttle consists of a classical mechanical pendulum situated between two capacitor plates. The metallic pendulum enables mechanical transfer of electrons between the plates, hence allowing to directly trace electron shuttling in the time domain. By applying a high voltage to the plates, we drive the system into a controlled nonlinear response, where we observe period doubling.

Schedule and complex motion of shuttle bus induced by periodic inflow of passengers

Science.gov (United States)

Nagatani, Takashi; Naito, Yuichi

2011-09-01

We have studied the dynamic behavior of a bus in the shuttle bus transportation with a periodic inflow. A bus schedule is closely related to the dynamics. We present the modified circle map model for the dynamics of the shuttle bus. The motion of the shuttle bus depends on the loading parameter and the inflow period. The shuttle bus displays the periodic, quasi-periodic, and chaotic motions with varying both loading parameter and inflow rate.

Pair angular correlations for pions, kaons and protons in proton-proton collisions in ALICE

CERN Document Server

Zaborowska, Anna

2014-01-01

This thesis presents the correlation functions in $\\Delta\\eta\\, \\Delta\\phi$ space for pairs of pions, kaons and protons. The studies were carried out on the set of proton-proton collisions at the centre-of-mass energy $\\sqrt{s}$ = 7 TeV, obtained in ALICE, A Large Ion Collider Experiment at CERN, the European Organization for Nuclear Research. The analysis was performed for two charge combinations (like-sign pairs and unlike-sign pairs) as well as for three multiplicity ranges. Angular correlations are a rich source of information about the elementary particles behaviour. They result in from the interplay of numerous effects, including resonances’ decays, Coulomb interactions and energy and momentum conservation. In case of identical particles quantum statistics needs to be taken into account. Moreover, particles differ in terms of quark content. Kaons, carrying the strange quark obey the strangeness conservation law. In the production of protons baryon number must be conserved. These features are reflected...

Aerospace News: Space Shuttle Commemoration. Volume 2, No. 7

Science.gov (United States)

2011-01-01

The complex space shuttle design was comprised of four components: the external tank, two solid rocket boosters (SRB), and the orbiter vehicle. Six orbiters were used during the life of the program. In order of introduction into the fleet, they were: Enterprise (a test vehicle), Columbia, Challenger, Discovery, Atlantis and Endeavour. The space shuttle had the unique ability to launch into orbit, perform on-orbit tasks, return to earth and land on a runway. It was an orbiting laboratory, International Space Station crew delivery and supply replenisher, satellite launcher and payload delivery vehicle, all in one. Except for the external tank, all components of the space shuttle were designed to be reusable for many flights. ATK s reusable solid rocket motors (RSRM) were designed to be flown, recovered, and the metal components reused 20 times. Following each space shuttle launch, the SRBs would parachute into the ocean and be recovered by the Liberty Star and Freedom Star recovery ships. The recovered boosters would then be received at the Cape Canaveral Air Force Station Hangar AF facility for disassembly and engineering post-flight evaluation. At Hangar AF, the RSRM field joints were demated and the segments prepared to be returned to Utah by railcar. The segments were then shipped to ATK s facilities in Clearfield for additional evaluation prior to washout, disassembly and refurbishment. Later the refurbished metal components would be transported to ATK s Promontory facilities to begin a new cycle. ATK s RSRMs were manufactured in Promontory, Utah. During the Space Shuttle Program, ATK supported NASA s Marshall Space Flight Center whose responsibility was for all propulsion elements on the program, including the main engines and solid rocket motors. On launch day for the space shuttle, ATK s Launch Site Operations employees at Kennedy Space Center (KSC) provided lead engineering support for ground operations and NASA s chief engineer. It was ATK s responsibility

Linking the space shuttle and space stations early docking technologies from concept to implementation

CERN Document Server

Shayler, David J

2017-01-01

How could the newly authorized space shuttle help in the U.S. quest to build a large research station in Earth orbit? As a means of transporting goods, the shuttle could help supply the parts to the station. But how would the two entitles be physically linked? Docking technologies had to constantly evolve as the designs of the early space stations changed. It was hoped the shuttle would make missions to the Russian Salyut and American Skylab stations, but these were postponed until the Mir station became available, while plans for getting a new U. S. space station underway were stalled. In Linking the Space Shuttle and Space Stations, the author delves into the rich history of the Space Shuttle and its connection to these early space stations, culminating in the nine missions to dock the shuttle to Mir. By 1998, after nearly three decades of planning and operations, shuttle missions to Mir had resulted in: • A proven system to link up the space shuttle to a space station • Equipment and hands-on experienc...

2009 Space Shuttle Probabilistic Risk Assessment Overview

Science.gov (United States)

Hamlin, Teri L.; Canga, Michael A.; Boyer, Roger L.; Thigpen, Eric B.

2010-01-01

Loss of a Space Shuttle during flight has severe consequences, including loss of a significant national asset; loss of national confidence and pride; and, most importantly, loss of human life. The Shuttle Probabilistic Risk Assessment (SPRA) is used to identify risk contributors and their significance; thus, assisting management in determining how to reduce risk. In 2006, an overview of the SPRA Iteration 2.1 was presented at PSAM 8 [1]. Like all successful PRAs, the SPRA is a living PRA and has undergone revisions since PSAM 8. The latest revision to the SPRA is Iteration 3. 1, and it will not be the last as the Shuttle program progresses and more is learned. This paper discusses the SPRA scope, overall methodology, and results, as well as provides risk insights. The scope, assumptions, uncertainties, and limitations of this assessment provide risk-informed perspective to aid management s decision-making process. In addition, this paper compares the Iteration 3.1 analysis and results to the Iteration 2.1 analysis and results presented at PSAM 8.

Shuttle Planning for Link Closures in Urban Public Transport Networks

NARCIS (Netherlands)

van der Hurk, E.; Koutsopoulos, H.; Wilson, N.H.M.; Kroon, L.G.; Maroti, G.

2016-01-01

Urban public transport systems must periodically close certain links for maintenance, which can have significant effects on the service provided to passengers. In practice, the effects of closures are mitigated by replacing the closed links with a simple shuttle service. However, alternative shuttle

Dynamical localization of two electrons in triple-quantum-dot shuttles

International Nuclear Information System (INIS)

Qu, Jinxian; Duan, Suqing; Yang, Ning

2012-01-01

The dynamical localization phenomena in two-electron quantum-dot shuttles driven by an ac field have been investigated and analyzed by the Floquet theory. The dynamical localization occurs near the anti-crossings in Floquet eigenenergy spectrum. The oscillation of the quantum-dot shuttles may increase the possibility of the dynamical localization. Especially, even if the two electrons are initialized in two neighbor dots, they can be localized there for appropriate intensity of the driven field. The studies may help the understanding of dynamical localization in electron shuttles and expand the application potential of nanoelectromechanical devices. -- Highlights: ► The dynamical localization in electron shuttle is studied by Floquet theory. ► There is a relation between quasi-energy anti-crossings and dynamical localization. ► The oscillation of quantum dot increases the dynamical localization. ► Even the electrons are initialized in different dots, the localization can occur.

A Comparison Between Orion Automated and Space Shuttle Rendezvous Techniques

Science.gov (United States)

Ruiz, Jose O,; Hart, Jeremy

2010-01-01

The Orion spacecraft will replace the space shuttle and will be the first human spacecraft since the Apollo program to leave low earth orbit. This vehicle will serve as the cornerstone of a complete space transportation system with a myriad of mission requirements necessitating rendezvous to multiple vehicles in earth orbit, around the moon and eventually beyond . These goals will require a complex and robust vehicle that is, significantly different from both the space shuttle and the command module of the Apollo program. Historically, orbit operations have been accomplished with heavy reliance on ground support and manual crew reconfiguration and monitoring. One major difference with Orion is that automation will be incorporated as a key element of the man-vehicle system. The automated system will consist of software devoted to transitioning between events based on a master timeline. This effectively adds a layer of high level sequencing that moves control of the vehicle from one phase to the next. This type of automated control is not entirely new to spacecraft since the shuttle uses a version of this during ascent and entry operations. During shuttle orbit operations however many of the software modes and hardware switches must be manually configured through the use of printed procedures and instructions voiced from the ground. The goal of the automation scheme on Orion is to extend high level automation to all flight phases. The move towards automation represents a large shift from current space shuttle operations, and so these new systems will be adopted gradually via various safeguards. These include features such as authority-to-proceed, manual down modes, and functional inhibits. This paper describes the contrast between the manual and ground approach of the space shuttle and the proposed automation of the Orion vehicle. I will introduce typical orbit operations that are common to all rendezvous missions and go on to describe the current Orion automation

Seismic excitation by space shuttles

Science.gov (United States)

Kanamori, H.; Mori, J.; Sturtevant, B.; Anderson, D.L.; Heaton, T.

1992-01-01

Shock waves generated by the space shuttles Columbia (August 13, 1989), Atlantis (April 11, 1991) and Discovery (September 18, 1991) on their return to Edwards Air Force Base, California, were recorded by TERRAscope (Caltech's broadband seismic network), the Caltech-U.S.G.S Southern California Seismic Network (SCSN), and the University of Southern California (USC) Los Angeles Basin Seismic Network. The spatial pattern of the arrival times exhibits hyperbolic shock fronts from which the path, velocity and altitude of the space shuttle could be determined. The shock wave was acoustically coupled to the ground, converted to a seismic wave, and recorded clearly at the broadband TERRAscope stations. The acoustic coupling occurred very differently depending on the conditions of the Earth's surface surrounding the station. For a seismic station located on hard bedrock, the shock wave (N wave) was clearly recorded with little distortion. Aside from the N wave, very little acoustic coupling of the shock wave energy to the ground occurred at these sites. The observed N wave record was used to estimate the overpressure of the shock wave accurately; a pressure change of 0.5 to 2.2 mbars was obtained. For a seismic station located close to the ocean or soft sedimentary basins, a significant amount of shock wave energy was transferred to the ground through acoustic coupling of the shock wave and the oceanic Rayleigh wave. A distinct topography such as a mountain range was found effective to couple the shock wave energy to the ground. Shock wave energy was also coupled to the ground very effectively through large man made structures such as high rise buildings and offshore oil drilling platforms. For the space shuttle Columbia, in particular, a distinct pulse having a period of about 2 to 3 seconds was observed, 12.5 s before the shock wave, with a broadband seismograph in Pasadena. This pulse was probably excited by the high rise buildings in downtown Los Angeles which were

Proton Fast Ignition

International Nuclear Information System (INIS)

Key, M H; Freeman, R R; Hatchett, S P; MacKinnon, A J; Patel, P K; Snavely, R A; Stephens, R B

2006-04-01

Fast ignition (FI) by a laser generated ballistically focused proton beam is a more recently proposed alternative to the original concept of FI by a laser generated beam of relativistic electrons. It has potential advantages in less complex energy transport into dense plasma. Recent successful target heating experiments motivate further investigation of the feasibility of proton fast ignition. The concept, the physics and characteristics of the proton beams, the recent experimental work on focusing of the beams and heating of solid targets and the overall prospects for proton FI are discussed

Development of a prototype specialist shuttle vehicle for chipped woodfuel

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-06-01

This report gives details of a project to develop and test a specialist chip shuttle vehicle for conveying woodchips out of the forest with the aim of reducing the cost of woodfuel production. The design objectives are described and include the need to allow easy transfer of the chips from the chipper to the shuttle and on into haulage units, good performance and manoeuvrability on and off roads, and high-tip capacity. Estimates of the improved production and reduced woodfuel production costs are discussed along with the anticipated satisfactory operation of the chipper-shuttle combination in a forestry site.

Modal Testing of Seven Shuttle Cargo Elements for Space Station

Science.gov (United States)

Kappus, Kathy O.; Driskill, Timothy C.; Parks, Russel A.; Patterson, Alan (Technical Monitor)

2001-01-01

From December 1996 to May 2001, the Modal and Control Dynamics Team at NASA's Marshall Space Flight Center (MSFC) conducted modal tests on seven large elements of the International Space Station. Each of these elements has been or will be launched as a Space Shuttle payload for transport to the International Space Station (ISS). Like other Shuttle payloads, modal testing of these elements was required for verification of the finite element models used in coupled loads analyses for launch and landing. The seven modal tests included three modules - Node, Laboratory, and Airlock, and four truss segments - P6, P3/P4, S1/P1, and P5. Each element was installed and tested in the Shuttle Payload Modal Test Bed at MSFC. This unique facility can accommodate any Shuttle cargo element for modal test qualification. Flexure assemblies were utilized at each Shuttle-to-payload interface to simulate a constrained boundary in the load carrying degrees of freedom. For each element, multiple-input, multiple-output burst random modal testing was the primary approach with controlled input sine sweeps for linearity assessments. The accelerometer channel counts ranged from 252 channels to 1251 channels. An overview of these tests, as well as some lessons learned, will be provided in this paper.

Schedule and complex motion of shuttle bus induced by periodic inflow of passengers

International Nuclear Information System (INIS)

Nagatani, Takashi; Naito, Yuichi

2011-01-01

We have studied the dynamic behavior of a bus in the shuttle bus transportation with a periodic inflow. A bus schedule is closely related to the dynamics. We present the modified circle map model for the dynamics of the shuttle bus. The motion of the shuttle bus depends on the loading parameter and the inflow period. The shuttle bus displays the periodic, quasi-periodic, and chaotic motions with varying both loading parameter and inflow rate. -- Highlights: → We studied the dynamic behavior of a bus in the shuttle bus transportation. → We presented the modified circle map model for the bus schedule. → We clarified the dependence of the tour time on both loading parameter and inflow period.

Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes

Science.gov (United States)

Pettersen, H. E. S.; Alme, J.; Biegun, A.; van den Brink, A.; Chaar, M.; Fehlker, D.; Meric, I.; Odland, O. H.; Peitzmann, T.; Rocco, E.; Ullaland, K.; Wang, H.; Yang, S.; Zhang, C.; Röhrich, D.

2017-07-01

Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue introduces range uncertainties of the order of 2-3% of the range, uncertainties that are contributing to an increase of the necessary planning margins added to the target volume in a patient. Imaging methods and modalities, such as Dual Energy CT and proton CT, have come into consideration in the pursuit of obtaining an as good as possible estimate of the proton stopping power. In this study, a Digital Tracking Calorimeter is benchmarked for proof-of-concept for proton CT purposes. The Digital Tracking Calorimeter was originally designed for the reconstruction of high-energy electromagnetic showers for the ALICE-FoCal project. The presented prototype forms the basis for a proton CT system using a single technology for tracking and calorimetry. This advantage simplifies the setup and reduces the cost of a proton CT system assembly, and it is a unique feature of the Digital Tracking Calorimeter concept. Data from the AGORFIRM beamline at KVI-CART in Groningen in the Netherlands and Monte Carlo simulation results are used to in order to develop a tracking algorithm for the estimation of the residual ranges of a high number of concurrent proton tracks. High energy protons traversing the detector leave a track through the sensor layers. These tracks are spread out through charge diffusion processes. A charge diffusion model is applied for acquisition of estimates of the deposited energy of the protons in each sensor layer by using the size of the charge diffused area. A model fit of the Bragg Curve is applied to each reconstructed track and through this, estimating the residual range of each proton. The range of the individual protons can at present be estimated with a resolution of 4%. The readout system for this prototype is able to

Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes

Energy Technology Data Exchange (ETDEWEB)

Pettersen, H.E.S., E-mail: helge.pettersen@helse-bergen.no [Department of Oncology and Medical Physics, Haukeland University Hospital, Postbox 1400, 5021 Bergen (Norway); Department of Physics and Technology, University of Bergen, Postbox 7803, 5020 Bergen (Norway); Alme, J. [Department of Physics and Technology, University of Bergen, Postbox 7803, 5020 Bergen (Norway); Biegun, A. [Kernfysisch Versneller Instituut, University of Groningen, NL-9747 AA Groningen (Netherlands); Brink, A. van den [Nikhef, Utrecht University, Postbox 41882, 1009 DB Amsterdam (Netherlands); Chaar, M.; Fehlker, D. [Department of Physics and Technology, University of Bergen, Postbox 7803, 5020 Bergen (Norway); Meric, I. [Department of Electrical Engineering, Bergen University College, Postbox 7030, 5020 Bergen (Norway); Odland, O.H. [Department of Oncology and Medical Physics, Haukeland University Hospital, Postbox 1400, 5021 Bergen (Norway); Peitzmann, T.; Rocco, E. [Nikhef, Utrecht University, Postbox 41882, 1009 DB Amsterdam (Netherlands); Ullaland, K. [Department of Physics and Technology, University of Bergen, Postbox 7803, 5020 Bergen (Norway); Wang, H. [Nikhef, Utrecht University, Postbox 41882, 1009 DB Amsterdam (Netherlands); Yang, S. [Department of Physics and Technology, University of Bergen, Postbox 7803, 5020 Bergen (Norway); Zhang, C. [Nikhef, Utrecht University, Postbox 41882, 1009 DB Amsterdam (Netherlands); Röhrich, D. [Department of Physics and Technology, University of Bergen, Postbox 7803, 5020 Bergen (Norway)

2017-07-11

Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue introduces range uncertainties of the order of 2–3% of the range, uncertainties that are contributing to an increase of the necessary planning margins added to the target volume in a patient. Imaging methods and modalities, such as Dual Energy CT and proton CT, have come into consideration in the pursuit of obtaining an as good as possible estimate of the proton stopping power. In this study, a Digital Tracking Calorimeter is benchmarked for proof-of-concept for proton CT purposes. The Digital Tracking Calorimeter was originally designed for the reconstruction of high-energy electromagnetic showers for the ALICE-FoCal project. The presented prototype forms the basis for a proton CT system using a single technology for tracking and calorimetry. This advantage simplifies the setup and reduces the cost of a proton CT system assembly, and it is a unique feature of the Digital Tracking Calorimeter concept. Data from the AGORFIRM beamline at KVI-CART in Groningen in the Netherlands and Monte Carlo simulation results are used to in order to develop a tracking algorithm for the estimation of the residual ranges of a high number of concurrent proton tracks. High energy protons traversing the detector leave a track through the sensor layers. These tracks are spread out through charge diffusion processes. A charge diffusion model is applied for acquisition of estimates of the deposited energy of the protons in each sensor layer by using the size of the charge diffused area. A model fit of the Bragg Curve is applied to each reconstructed track and through this, estimating the residual range of each proton. The range of the individual protons can at present be estimated with a resolution of 4%. The readout system for this prototype is able to

Two-proton radioactivity in proton-rich fp shell nuclei at high spin

Energy Technology Data Exchange (ETDEWEB)

Aggarwal, Mamta [Nuclear Science Centre, Aruna Asaf Ali Marg, Post Box 10502, New Delhi 110067 (India)

2006-07-15

Two-proton radioactivity in extremely proton-rich fp shell nuclei at high spins is investigated in a theoretical framework. Separation energy and entropy fluctuate with spin and hence affect the location of the proton drip line.

Two-proton radioactivity in proton-rich fp shell nuclei at high spin

International Nuclear Information System (INIS)

Aggarwal, Mamta

2006-01-01

Two-proton radioactivity in extremely proton-rich fp shell nuclei at high spins is investigated in a theoretical framework. Separation energy and entropy fluctuate with spin and hence affect the location of the proton drip line

Surface chloride salt formation on Space Shuttle exhaust alumina

Science.gov (United States)

Cofer, W. R., III; Pellett, G. L.; Sebacher, D. I.; Wakelyn, N. T.

1984-01-01

Aluminum oxide samples from the exhaust of Space Shuttle launches STS-1, STS-4, STS-5, and STS-6 were collected from surfaces on or around the launch pad complex and chemically analyzed. The results indicate that the particulate solid-propellant rocket motor (SRM) alumina was heavily chlorided. Concentrations of water-soluble aluminum (III) ion were large, suggesting that the surface of the SRM alumina particles was rendered soluble by prior reactions with HCl and H2O in the SRM exhaust cloud. These results suggest that Space Shuttle exhaust alumina particles are good sites for nucleation and condensation of atmospheric water. Laboratory experiments conducted at 220 C suggest that partial surface chloriding of alumina may occur in hot Space Shuttle exhaust plumes.

The influence of the Coulomb-distortion effect on proton-proton observables

International Nuclear Information System (INIS)

Plessas, W.; Mathelitsch, L.

1980-01-01

The effect of the Coulomb distortion of the strong interaction is studied on the basis of nucleon-nucleon observables. In particular, cross sections, polarizations, spin-correlation parameters, and spin-transfer coefficients are considered for proton-proton as well as neutron-neutron scattering at laboratory kinetic energies Esub(Lab) = 10, 20, and 50 MeV. The calculations are performed for the meson-theoretical PARIS potential, the nonlocal separable GRAZ potential and also using the Arndt-Hackman-Roper parametrization of proton-proton scattering phase shifts. Important conclusions are drawn with respect to phenomenological phase-shift analyses. (Auth.)

Proton-proton Scattering Above 3 GeV/c

Energy Technology Data Exchange (ETDEWEB)

A. Sibirtsev, J. Haidenbauer, H.-W. Hammer S. Krewald ,Ulf-G. Meissner

2010-01-01

A large set of data on proton-proton differential cross sections, analyzing powers and the double-polarization parameter A{sub NN} is analyzed employing the Regge formalism. We find that the data available at proton beam momenta from 3 GeV/c to 50 GeV/c exhibit features that are very well in line with the general characteristics of Regge phenomenology and can be described with a model that includes the {rho}, {omega}, f{sub 2}, and a{sub 2} trajectories and single-Pomeron exchange. Additional data, specifically for spin-dependent observables at forward angles, would be very helpful for testing and refining our Regge model.

High intensity proton accelerator and its application (Proton Engineering Center)

International Nuclear Information System (INIS)

Tanaka, Shun-ichi

1995-01-01

A plan called PROTON ENGINEERING CENTER has been proposed in JAERI. The center is a complex composed of research facilities and a beam shape and storage ring based on a proton linac with an energy of 1.5 GeV and an average current of 10 mA. The research facilities planned are OMEGA·Nuclear Energy Development Facility, Neutron Facility for Material Irradiation, Nuclear Data Experiment Facility, Neutron Factory, Meson Factory, Spallation Radioisotope Beam Facility, and Medium Energy Experiment Facility, where high intensity proton beam and secondary particle beams such as neutrons, π-mesons, muons, and unstable isotopes originated from the protons are available for promoting the innovative research of nuclear energy and basic science and technology. (author)

Inter- and intra-annular proton exchange in gaseous benzylbenzenium ions (protonated diphenylmethane)

OpenAIRE

Kuck, Dietmar; Bäther, Wolfgang

1986-01-01

Two distinct proton exchange reactions occur in metastable gaseous benzylbenzenium ions, generated by isobutane chemical ionization of diphenylmethane and four deuterium-labelled analogues. Whereas the proton ring-walk at the benzenium moiety is fast giving rise to a completely random intraannular proton exchange, the interannular proton exchange is surprisingly slow and competes with the elimination of benzene. A kinetic isotope effect of kH/kD= 5 has been determined for the interannular pro...

Relativistic total and differential cross section proton--proton electron--positron pair production calculation

International Nuclear Information System (INIS)

Rubinstein, J.E.

1976-01-01

Circle Feynman diagrams for a specific permutation of variables along with their corresponding algebraic expressions are presented to evaluate [H] 2 for proton-proton electron-positron pair production. A Monte Carlo integration technique is introduced and is used to set up the multiple integral expression for the total pair production cross section. The technique is first applied to the Compton scattering problem and then to an arbitrary multiple integral. The relativistic total cross section for proton-proton electron-positron pair production was calculated for eight different values of incident proton energy. A variety of differential cross sections were calculated for the above energies. Angular differential cross section distributions are presented for the electron, positron, and proton. Invariant mass differential cross section distributions are done both with and without the presence of [H] 2 . Both WGHT and log 10 (TOTAL) distributions were also obtained. The general behavioral trends of the total and differential cross sections for proton-proton electron-positron pair production are presented. The range of validity for this calculation is from 0 to about 200 MeV

Surface proton transport of fully protonated poly(aspartic acid) thin films on quartz substrates

Science.gov (United States)

Nagao, Yuki; Kubo, Takahiro

2014-12-01

Thin film structure and the proton transport property of fully protonated poly(aspartic acid) (P-Asp100) have been investigated. An earlier study assessed partially protonated poly(aspartic acid), highly oriented thin film structure and enhancement of the internal proton transport. In this study of P-Asp100, IR p-polarized multiple-angle incidence resolution (P-MAIR) spectra were measured to investigate the thin film structure. The obtained thin films, with thicknesses of 120-670 nm, had no oriented structure. Relative humidity dependence of the resistance, proton conductivity, and normalized resistance were examined to ascertain the proton transport property of P-Asp100 thin films. The obtained data showed that the proton transport of P-Asp100 thin films might occur on the surface, not inside of the thin film. This phenomenon might be related with the proton transport of the biological system.

Quantitative risk analysis of a space shuttle subsystem

International Nuclear Information System (INIS)

Frank, M.V.

1989-01-01

This paper reports that in an attempt to investigate methods for risk management other than qualitative analysis techniques, NASA has funded pilot study quantitative risk analyses for space shuttle subsystems. The authors performed one such study of two shuttle subsystems with McDonnell Douglas Astronautics Company. The subsystems were the auxiliary power units (APU) on the orbiter, and the hydraulic power units on the solid rocket booster. The technology and results of the APU study are presented in this paper. Drawing from a rich in-flight database as well as from a wealth of tests and analyses, the study quantitatively assessed the risk of APU-initiated scenarios on the shuttle during all phases of a flight mission. Damage states of interest were loss of crew/vehicle, aborted mission, and launch scrub. A quantitative risk analysis approach to deciding on important items for risk management was contrasted with the current NASA failure mode and effects analysis/critical item list approach

Shuttle Orbiter Active Thermal Control Subsystem design and flight experience

Science.gov (United States)

Bond, Timothy A.; Metcalf, Jordan L.; Asuncion, Carmelo

1991-01-01

The paper examines the design of the Space Shuttle Orbiter Active Thermal Control Subsystem (ATCS) constructed for providing the vehicle and payload cooling during all phases of a mission and during ground turnaround operations. The operation of the Shuttle ATCS and some of the problems encountered during the first 39 flights of the Shuttle program are described, with special attention given to the major problems encountered with the degradation of the Freon flow rate on the Orbiter Columbia, the Flash Evaporator Subsystem mission anomalies which occurred on STS-26 and STS-34, and problems encountered with the Ammonia Boiler Subsystem. The causes and the resolutions of these problems are discussed.

Impact of shuttle environment on prelaunch handling of nickel-hydrogen batteries

Science.gov (United States)

Green, R. S.

1986-01-01

Deployment of the American Satellite Company 1 spacecraft for the Space Shuttle Discovery in August 1985 set a new milestone in nickel-hydrogen battery technology. This communications satellite is equipped with two 35 Ah nickel-hydrogen batteries and it is the first such satellite launched into orbit via the Space Shuttle. The prelaunch activities, combined with the environmental constraints onboard the Shuttle, led to the development of a new battery handling procedure. An outline of the prelaunch activities, with particular attention to battery charging, is presented.

PS proton source

CERN Multimedia

1959-01-01

The first proton source used at CERN's Proton Synchrotron (PS) which started operation in 1959. This is CERN's oldest accelerator still functioning today (2018). It is part of the accelerator chain that supplies proton beams to the Large Hadron Collider. The source is a Thonemann type. In order to extract and accelerate the protons at high energy, a high frequency electrical field is used (140Mhz). The field is transmitted by a coil around a discharge tube in order to maintain the gas hydrogen in an ionised state. An electrical field pulse, in the order of 15kV, is then applied via an impulse transformer between anode and cathode of the discharge tube. The electrons and protons of the plasma formed in the ionised gas in the tube, are then separated. Currents in the order of 200mA during 100 microseconds have benn obtained with this type of source.

The Evolution of the Rendezvous Profile During the Space Shuttle Program

Science.gov (United States)

Summa, William R.

2010-01-01

The rendezvous and proximity operations approach design techniques for space shuttle missions has changed significantly during the life of the program in response to new requirements that were not part of the original mission design. The flexibility of the shuttle onboard systems design and the mission planning process has allowed the program to meet these requirements. The design of the space shuttle and the shift from docking to grappling with a robotic ann prevented use of legacy Apollo rendezvous techniques. Over the life of the shuttle program the rendezvous profile has evolved due to several factors, including lowering propellant consumption and increasing flexibility in mission planning. Many of the spacecraft that the shuttle rendezvoused with had unique requirements that drove the creation of mission-unique proximity operations. The dockings to the Russian Mir space station and International Space Station (ISS) required further evolution of rendezvous and proximity operations techniques and additional sensors to enhance crew situational awareness. After the Columbia accident, a Rendezvous Pitch Maneuver (RPM) was added to allow tile photography from ISS. Lessons learned from these rendezvous design changes are applicable to future vehicle designs and operations concepts.

Correlation of Space Shuttle Landing Performance with Post-Flight Cardiovascular Dysfunction

Science.gov (United States)

McCluskey, R.

2004-01-01

Introduction: Microgravity induces cardiovascular adaptations resulting in orthostatic intolerance on re-exposure to normal gravity. Orthostasis could interfere with performance of complex tasks during the re-entry phase of Shuttle landings. This study correlated measures of Shuttle landing performance with post-flight indicators of orthostatic intolerance. Methods: Relevant Shuttle landing performance parameters routinely recorded at touchdown by NASA included downrange and crossrange distances, airspeed, and vertical speed. Measures of cardiovascular changes were calculated from operational stand tests performed in the immediate post-flight period on mission commanders from STS-41 to STS-66. Stand test data analyzed included maximum standing heart rate, mean increase in maximum heart rate, minimum standing systolic blood pressure, and mean decrease in standing systolic blood pressure. Pearson correlation coefficients were calculated with the null hypothesis that there was no statistically significant linear correlation between stand test results and Shuttle landing performance. A correlation coefficient? 0.5 with a pcorrelations between landing performance and measures of post-flight cardiovascular dysfunction. Discussion: There was no evidence that post-flight cardiovascular stand test data correlated with Shuttle landing performance. This implies that variations in landing performance were not due to space flight-induced orthostatic intolerance.

First Extraction of Transversity from a Global Analysis of Electron-Proton and Proton-Proton Data

Science.gov (United States)

Radici, Marco; Bacchetta, Alessandro

2018-05-01

We present the first extraction of the transversity distribution in the framework of collinear factorization based on the global analysis of pion-pair production in deep-inelastic scattering and in proton-proton collisions with a transversely polarized proton. The extraction relies on the knowledge of dihadron fragmentation functions, which are taken from the analysis of electron-positron annihilation data. For the first time, the transversity is extracted from a global analysis similar to what is usually done for the spin-averaged and helicity distributions. The knowledge of transversity is important for, among other things, detecting possible signals of new physics in high-precision low-energy experiments.

NASA study backs SSTO, urges shuttle phaseout

Science.gov (United States)

Asker, James R.

1994-03-01

A brief discusion of a Congressionally ordered NASA study on how to meet future US Government space launch needs is presented. Three options were examined: (1) improvement ofthe Space Shuttle; (2) development of expendable launch vehicles (ELVs); and (3) development of a single-stage-to-orbit (SSTO), manned vehicle that is reusable with advanced technology. After examining the three options, it was determined that the most economical approach to space access through the year 2030 would be to develop the SSTO vehicle and phase out Space Shuttle operations within 15 years and ELVs within 20 years. Other aspects of the study's findings are briefly covered.

Radiation dosimetry for the space shuttle program

International Nuclear Information System (INIS)

Jones, K.L.; Richmond, R.G.; Cash, B.L.

1985-01-01

Radiation measurements aboard the Space Shuttle are made to record crew doses for medical records, to verify analytical shielding calculations used in dose predictions and to provide dosimetry support for radiation sensitive payloads and experiments. Low cost systems utilizing thermoluminescent dosimeters, nuclear track detectors and activation foils have been developed to fulfill these requirements. Emphasis has been placed on mission planning and dose prediction. As a result, crew doses both inside the orbiter and during extra-vehicular activities have been reasonable low. Brief descriptions of the space radiation environment, dose prediction models, and radiation measurement systems are provided, along with a summary of the results for the first fourteen Shuttle flights

Proton transfer events in GFP.

Science.gov (United States)

Di Donato, Mariangela; van Wilderen, Luuk J G W; Van Stokkum, Ivo H M; Stuart, Thomas Cohen; Kennis, John T M; Hellingwerf, Klaas J; van Grondelle, Rienk; Groot, Marie Louise

2011-09-28

Proton transfer is one of the most important elementary processes in biology. Green fluorescent protein (GFP) serves as an important model system to elucidate the mechanistic details of this reaction, because in GFP proton transfer can be induced by light absorption. Illumination initiates proton transfer through a 'proton-wire', formed by the chromophore (the proton donor), water molecule W22, Ser205 and Glu222 (the acceptor), on a picosecond time scale. To obtain a more refined view of this process, we have used a combined approach of time resolved mid-infrared spectroscopy and visible pump-dump-probe spectroscopy to resolve with atomic resolution how and how fast protons move through this wire. Our results indicate that absorption of light by GFP induces in 3 ps (10 ps in D(2)O) a shift of the equilibrium positions of all protons in the H-bonded network, leading to a partial protonation of Glu222 and to a so-called low barrier hydrogen bond (LBHB) for the chromophore's proton, giving rise to dual emission at 475 and 508 nm. This state is followed by a repositioning of the protons on the wire in 10 ps (80 ps in D(2)O), ultimately forming the fully deprotonated chromophore and protonated Glu222.

Effects of thruster firings on the shuttle's plasma and electric field environment

International Nuclear Information System (INIS)

Machuzak, J.S.; Burke, W.J.; Retterer, J.M.; Hunton, D.E.; Jasperse, J.R.; Smiddy, M.

1993-01-01

Simultaneous plasma and AC/DC electric field measurements taken during the space shuttle mission STS-4 at times of prolonged thruster firings are analyzed and cross correlated. Depending on the orientation of the shuttle's velocity vector to the magnetic field, ion densities and electric field wave spectra were enhanced or decreased. The systematic picture of interactions within the shuttle's plasma/neutral gas environment of Cairns and Gurnett (1991b) is confirmed and extended. Waves are excited by outgassed and thruster-ejected molecules that ionize in close proximity to the shuttle. On time scales significantly less than an ion gyroperiod, the newly created ions act as beams in the background plasma. These beams are sources of VLF waves that propagate near the shuttle and intensify during thruster firings. Plasma density depletions and/or the shuttle's geometry may hinder wave detection in the payload bay. A modified two-stream analysis indicates that beam components propagating at large angles to the magnetic field are unstable to the growth of lower hybrid waves. The beam-excited, lower hybrid waves heat some electrons to sufficient energies to produce impact ionization. Empirical evidence for other wave-growth mechanisms outside the lower-hybrid band is presented. 42 refs., 15 figs., 3 tabs

Large-Scale Liquid Hydrogen Tank Rapid Chill and Fill Testing for the Advanced Shuttle Upper Stage Concept

Science.gov (United States)

Flachbart, R. H.; Hedayat, A.; Holt, K. A.; Sims, J.; Johnson, E. F.; Hastings, L. J.; Lak, T.

2013-01-01

Cryogenic upper stages in the Space Shuttle program were prohibited primarily due to a safety risk of a 'return to launch site' abort. An upper stage concept addressed this concern by proposing that the stage be launched empty and filled using shuttle external tank residuals after the atmospheric pressure could no longer sustain an explosion. However, only about 5 minutes was allowed for tank fill. Liquid hydrogen testing was conducted within a near-ambient environment using the multipurpose hydrogen test bed 638.5 ft3 (18m3) cylindrical tank with a spray bar mounted longitudinally inside. Although the tank was filled within 5 minutes, chilldown of the tank structure was incomplete, and excessive tank pressures occurred upon vent valve closure. Elevated tank wall temperatures below the liquid level were clearly characteristic of film boiling. The test results have substantial implications for on-orbit cryogen transfer since the formation of a vapor film would be much less inhibited due to the reduced gravity. However, the heavy tank walls could become an asset in normal gravity testing for on-orbit transfer, i.e., if film boiling in a nonflight weight tank can be inhibited in normal gravity, then analytical modeling anchored with the data could be applied to reduced gravity environments with increased confidence.

Sparse-view proton computed tomography using modulated proton beams

Energy Technology Data Exchange (ETDEWEB)

Lee, Jiseoc; Kim, Changhwan; Cho, Seungryong, E-mail: scho@kaist.ac.kr [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejon 305-701 (Korea, Republic of); Min, Byungjun [Department of Radiation Oncology, Kangbuk Samsung Hospital, 110–746 (Korea, Republic of); Kwak, Jungwon [Department of Radiation Oncology, Asan Medical Center, 138–736 (Korea, Republic of); Park, Seyjoon; Lee, Se Byeong [Proton Therapy Center, National Cancer Center, 410–769 (Korea, Republic of); Park, Sungyong [Proton Therapy Center, McLaren Cancer Institute, Flint, Michigan 48532 (United States)

2015-02-15

Purpose: Proton imaging that uses a modulated proton beam and an intensity detector allows a relatively fast image acquisition compared to the imaging approach based on a trajectory tracking detector. In addition, it requires a relatively simple implementation in a conventional proton therapy equipment. The model of geometric straight ray assumed in conventional computed tomography (CT) image reconstruction is however challenged by multiple-Coulomb scattering and energy straggling in the proton imaging. Radiation dose to the patient is another important issue that has to be taken care of for practical applications. In this work, the authors have investigated iterative image reconstructions after a deconvolution of the sparsely view-sampled data to address these issues in proton CT. Methods: Proton projection images were acquired using the modulated proton beams and the EBT2 film as an intensity detector. Four electron-density cylinders representing normal soft tissues and bone were used as imaged object and scanned at 40 views that are equally separated over 360°. Digitized film images were converted to water-equivalent thickness by use of an empirically derived conversion curve. For improving the image quality, a deconvolution-based image deblurring with an empirically acquired point spread function was employed. They have implemented iterative image reconstruction algorithms such as adaptive steepest descent-projection onto convex sets (ASD-POCS), superiorization method–projection onto convex sets (SM-POCS), superiorization method–expectation maximization (SM-EM), and expectation maximization-total variation minimization (EM-TV). Performance of the four image reconstruction algorithms was analyzed and compared quantitatively via contrast-to-noise ratio (CNR) and root-mean-square-error (RMSE). Results: Objects of higher electron density have been reconstructed more accurately than those of lower density objects. The bone, for example, has been reconstructed

Inelastic and diffraction dissociation cross-sections in proton-proton collisions with ALICE

CERN Multimedia

CERN. Geneva

2012-01-01

ALICE results on proton-proton inelastic and diffractive cross-section measurements performed at $\\sqrt{s}$ = 0.9 TeV, 2.76 TeV and 7 TeV are presented. The relative rates of single- and double- diffractive processes are measured by studying properties of gaps in the pseudorapidity distribution of charged particles. ALICE trigger efficiencies are determined for various classes of events, using a detector simulation validated with experimental data. The results are presented together with earlier measurements at proton-antiproton and proton-proton colliders at lower energies and with the measurements by other LHC experiments. Predictions by different theoretical models are compared to the data. We will also discuss the main theoretical problems in the field and present some of the recent developments.

Polarized proton beams

International Nuclear Information System (INIS)

Roser, T.

1995-01-01

The acceleration of polarized proton beams in circular accelerators is complicated by the presence of numerous depolarizing spin resonances. Careful and tedious minimization of polarization loss at each of these resonances allowed acceleration of polarized proton beams up to 22 GeV. It has been the hope that Siberian Snakes, which are local spin rotators inserted into ring accelerators, would eliminate these resonances and allow acceleration of polarized beams with the same ease and efficiency that is now routine for unpolarized beams. First tests at IUCF with a full Siberian Snake showed that the spin dynamics with a Snake can be understood in detail. The author now has results of the first tests of a partial Siberian Snake at the AGS, accelerating polarized protons to an energy of about 25 GeV. These successful tests of storage and acceleration of polarized proton beams open up new possibilities such as stored polarized beams for internal target experiments and high energy polarized proton colliders

Space Shuttle and Hypersonic Entry

Science.gov (United States)

Campbell, Charles H.; Gerstenmaier, William H.

2014-01-01

Fifty years of human spaceflight have been characterized by the aerospace operations of the Soyuz, of the Space Shuttle and, more recently, of the Shenzhou. The lessons learned of this past half decade are important and very significant. Particularly interesting is the scenario that is downstream from the retiring of the Space Shuttle. A number of initiatives are, in fact, emerging from in the aftermath of the decision to terminate the Shuttle program. What is more and more evident is that a new era is approaching: the era of the commercial usage and of the commercial exploitation of space. It is probably fair to say, that this is the likely one of the new frontiers of expansion of the world economy. To make a comparison, in the last 30 years our economies have been characterized by the digital technologies, with examples ranging from computers, to cellular phones, to the satellites themselves. Similarly, the next 30 years are likely to be characterized by an exponential increase of usage of extra atmospheric resources, as a result of more economic and efficient way to access space, with aerospace transportation becoming accessible to commercial investments. We are witnessing the first steps of the transportation of future generation that will drastically decrease travel time on our Planet, and significantly enlarge travel envelope including at least the low Earth orbits. The Steve Jobs or the Bill Gates of the past few decades are being replaced by the aggressive and enthusiastic energy of new entrepreneurs. It is also interesting to note that we are now focusing on the aerospace band, that lies on top of the aeronautical shell, and below the low Earth orbits. It would be a mistake to consider this as a known envelope based on the evidences of the flights of Soyuz, Shuttle and Shenzhou. Actually, our comprehension of the possible hypersonic flight regimes is bounded within really limited envelopes. The achievement of a full understanding of the hypersonic flight

WE-EF-303-09: Proton-Acoustic Range Verification in Proton Therapy

Energy Technology Data Exchange (ETDEWEB)

Ahmad, M; Xing, L [Stanford University School of Medicine, Stanford, CA (United States); Xiang, L [University of Oklahoma (OK), Norman, OK (United States)

2015-06-15

Purpose: We investigated proton-acoustic signals detection for range verification with current ultrasound instruments in typical clinical scenarios. Using simulations that included a realistic noise model, we determined the theoretical minimum dose required to generate detectable proton-acoustic signals. Methods: An analytical model was used to calculate the dose distributions and local pressure rise (per proton) for beams of different energy (100 and 160 MeV) and spot widths (1, 5, and 10 mm) in a water phantom. The acoustic waves propagating from the Bragg peak were modeled by the general 3D pressure wave equation and convolved with Gaussian kernels to simulate various proton pulse widths (0.1 – 10 ms). A realistic PZT ultrasound transducer (5 cm diameter) was simulated with a Butterworth band-pass filter, and ii) randomly generated noise based on a model of thermal noise in the transducer. The signal-to-noise ratio was calculated, determining the minimum number of protons and dose required per pulse. The maximum spatial resolution was also estimated from the signal spectrum. Results: The calculated noise in the transducer was 12–28 mPa, depending on the transducer center frequency (70–380 kHz). The minimum number of protons were on the order of 0.6–6 million per pulse, leading to 3–110 mGy dose per pulse at the Bragg peak, depending on the spot size. The acoustic signal consisted of lower frequencies for wider pulses, leading to lower noise levels, but also worse spatial resolution. The resolution was 1-mm for a 0.1-µs pulse width, but increased to 5-mm for a 10-µs pulse width. Conclusion: We have established minimum dose detection limits for proton-acoustic range validation. These limits correspond to a best case scenario with a large detector with no losses and only detector thermal noise. Feasible proton-acoustic range detection will require at least 10{sup 7} protons per pulse and pulse widths ≤ 1-µs.

Space Shuttle Communications Coverage Analysis for Thermal Tile Inspection

Science.gov (United States)

Kroll, Quin D.; Hwu, Shian U.; Upanavage, Matthew; Boster, John P.; Chavez, Mark A.

2009-01-01

The space shuttle ultra-high frequency Space-to-Space Communication System has to provide adequate communication coverage for astronauts who are performing thermal tile inspection and repair on the underside of the space shuttle orbiter (SSO). Careful planning and quantitative assessment are necessary to ensure successful system operations and mission safety in this work environment. This study assesses communication systems performance for astronauts who are working in the underside, non-line-of-sight shadow region on the space shuttle. All of the space shuttle and International Space Station (ISS) transmitting antennas are blocked by the SSO structure. To ensure communication coverage at planned inspection worksites, the signal strength and link margin between the SSO/ISS antennas and the extravehicular activity astronauts, whose line-of-sight is blocked by vehicle structure, was analyzed. Investigations were performed using rigorous computational electromagnetic modeling techniques. Signal strength was obtained by computing the reflected and diffracted fields along the signal propagation paths between transmitting and receiving antennas. Radio frequency (RF) coverage was determined for thermal tile inspection and repair missions using the results of this computation. Analysis results from this paper are important in formulating the limits on reliable communication range and RF coverage at planned underside inspection and repair worksites.

HAL/S programmer's guide. [for space shuttle program

Science.gov (United States)

Newbold, P. M.; Hotz, R. L.

1974-01-01

This programming language was developed for the flight software of the NASA space shuttle program. HAL/S is intended to satisfy virtually all of the flight software requirements of the space shuttle. To achieve this, HAL/s incorporates a wide range of features, including applications-oriented data types and organizations, real time control mechanisms, and constructs for systems programming tasks. As the name indicates, HAL/S is a dialect of the original HAL language previously developed. Changes have been incorporated to simplify syntax, curb excessive generality, or facilitate flight code emission.

Shuttle performance enhancement using an uprated OMS engine

Science.gov (United States)

Mallini, Charles J.; Boyd, William C.

1988-01-01

The NASA Space Shuttle's Orbital Maneuvering Engine (OME) has been investigated as the basis for an enhancement of Shuttle operational flexibility. The Johnson Space Center has given attention to an upgrading of the OME through the use of a gas generator-driven turbopump to raise engine specific impulse. Hardware tests have demonstrated the projected performance gains, which will yield an enhanced, intact ascent-abort capability, as well an an improved on-orbit payload and altitude capability. Attention is given to the application of these capabilities to the Hubble Space Telescope's deployment.

Proton computed tomography

International Nuclear Information System (INIS)

Hanson, K.M.

1978-01-01

The use of protons or other heavy charged particles instead of x rays in computed tomography (CT) is explored. The results of an experimental implementation of proton CT are presented. High quality CT reconstructions are obtained at an average dose reduction factor compared with an EMI 5005 x-ray scanner of 10:1 for a 30-cm-diameter phantom and 3.5:1 for a 20-cm diameter. The spatial resolution is limited by multiple Coulomb scattering to about 3.7 mm FWHM. Further studies are planned in which proton and x-ray images of fresh human specimens will be compared. Design considerations indicate that a clinically useful proton CT scanner is eminently feasible

Correlated stopping, proton clusters and higher order proton cumulants

Energy Technology Data Exchange (ETDEWEB)

Bzdak, Adam [AGH University of Science and Technology, Faculty of Physics and Applied Computer Science, Krakow (Poland); Koch, Volker [Lawrence Berkeley National Laboratory, Nuclear Science Division, Berkeley, CA (United States); Skokov, Vladimir [RIKEN/BNL, Brookhaven National Laboratory, Upton, NY (United States)

2017-05-15

We investigate possible effects of correlations between stopped nucleons on higher order proton cumulants at low energy heavy-ion collisions. We find that fluctuations of the number of wounded nucleons N{sub part} lead to rather nontrivial dependence of the correlations on the centrality; however, this effect is too small to explain the large and positive four-proton correlations found in the preliminary data collected by the STAR collaboration at √(s) = 7.7 GeV. We further demonstrate that, by taking into account additional proton clustering, we are able to qualitatively reproduce the preliminary experimental data. We speculate that this clustering may originate either from collective/multi-collision stopping which is expected to be effective at lower energies or from a possible first-order phase transition, or from (attractive) final state interactions. To test these ideas we propose to measure a mixed multi-particle correlation between stopped protons and a produced particle (e.g. pion, antiproton). (orig.)

Proton-90Zr interaction at sub-coulomb proton energies

International Nuclear Information System (INIS)

Laird, C.E.; Flynn, D.; Hershberger, R.L.; Gabbard, F.

1985-01-01

Measurements have been made of proton elastic scattering differential cross sections for proton scattering at 135 0 and 165 0 from 2 to 7 MeV, of inelastic scattering cross sections for proton scattering from 3.9 to 5.7 MeV, and of the radiative capture cross sections from 1.9 to 5.7 MeV detecting primary and cascade gamma rays. Optical potentials with Hauser-Feshbach and coupled-channel models have been used to analyze the data. This analysis yields an energy dependent absorptive potential of W = 2.63+.73 whose mean value of 5 MeV at E/sub p/ = 4 MeV is consistent with previously reported, but anomalously small values. The diffuseness of the real potential is .54 fm, which is consistent with values found for 92 Zr and 94 Zr. The adopted model values are used to deduce a total proton strength function which displays the features of both the 3s and the 3p single particle resonances

Proton beam therapy how protons are revolutionizing cancer treatment

CERN Document Server

Yajnik, Santosh

2013-01-01

Proton beam therapy is an emerging technology with promise of revolutionizing the treatment of cancer. While nearly half of all patients diagnosed with cancer in the US receive radiation therapy, the majority is delivered via electron accelerators, where photons are used to irradiate cancerous tissue. Because of the physical properties of photon beams, photons may deposit energy along their entire path length through the body. On the other hand, a proton beam directed at a tumor travels in a straight trajectory towards its target, gives off most of its energy at a defined depth called the Bragg peak, and then stops. While photons often deposit more energy within the healthy tissues of the body than within the cancer itself, protons can deposit most of their cancer-killing energy within the area of the tumor. As a result, in the properly selected patients, proton beam therapy has the ability to improve cure rates by increasing the dose delivered to the tumor and simultaneously reduce side-effects by decreasing...

Space Shuttle Probabilistic Risk Assessment (SPRA) Iteration 3.2

Science.gov (United States)

Boyer, Roger L.

2010-01-01

The Shuttle is a very reliable vehicle in comparison with other launch systems. Much of the risk posed by Shuttle operations is related to fundamental aspects of the spacecraft design and the environments in which it operates. It is unlikely that significant design improvements can be implemented to address these risks prior to the end of the Shuttle program. The model will continue to be used to identify possible emerging risk drivers and allow management to make risk-informed decisions on future missions. Potential uses of the SPRA in the future include: - Calculate risk impact of various mission contingencies (e.g. late inspection, crew rescue, etc.). - Assessing the risk impact of various trade studies (e.g. flow control valves). - Support risk analysis on mission specific events, such as in flight anomalies. - Serve as a guiding star and data source for future NASA programs.

Proton-rich nuclear statistical equilibrium

International Nuclear Information System (INIS)

Seitenzahl, I.R.; Timmes, F.X.; Marin-Lafleche, A.; Brown, E.; Magkotsios, G.; Truran, J.

2008-01-01

Proton-rich material in a state of nuclear statistical equilibrium (NSE) is one of the least studied regimes of nucleosynthesis. One reason for this is that after hydrogen burning, stellar evolution proceeds at conditions of an equal number of neutrons and protons or at a slight degree of neutron-richness. Proton-rich nucleosynthesis in stars tends to occur only when hydrogen-rich material that accretes onto a white dwarf or a neutron star explodes, or when neutrino interactions in the winds from a nascent proto-neutron star or collapsar disk drive the matter proton-rich prior to or during the nucleosynthesis. In this Letter we solve the NSE equations for a range of proton-rich thermodynamic conditions. We show that cold proton-rich NSE is qualitatively different from neutron-rich NSE. Instead of being dominated by the Fe-peak nuclei with the largest binding energy per nucleon that have a proton-to-nucleon ratio close to the prescribed electron fraction, NSE for proton-rich material near freezeout temperature is mainly composed of 56Ni and free protons. Previous results of nuclear reaction network calculations rely on this nonintuitive high-proton abundance, which this Letter explains. We show how the differences and especially the large fraction of free protons arises from the minimization of the free energy as a result of a delicate competition between the entropy and nuclear binding energy.

Measurement of the inelastic proton-proton cross section with the ATLAS detector

Energy Technology Data Exchange (ETDEWEB)

Zenis, Tibor [Comenius University Bratislava (Slovakia); Collaboration: ATLAS Collaboration

2013-04-15

A measurement of the inelastic proton-proton cross-section at centre-of-mass energy of Central diffraction in proton-proton collisions at {radical}(s) = 7TeV using the ATLAS detector at the Large Hadron Collider is presented. Events are selected by requiring hits in scintillator counters mounted in the forward region of the ATLAS detector and the dataset corresponding to an integrated luminosity of 20{mu}b{sup -1}. In addition, the total cross-section is studied as a function of the rapidity gap size measured with the inner detector and calorimetry.

NASTRAN analysis of the 1/8-scale space shuttle dynamic model

Science.gov (United States)

Bernstein, M.; Mason, P. W.; Zalesak, J.; Gregory, D. J.; Levy, A.

1973-01-01

The space shuttle configuration has more complex structural dynamic characteristics than previous launch vehicles primarily because of the high model density at low frequencies and the high degree of coupling between the lateral and longitudinal motions. An accurate analytical representation of these characteristics is a primary means for treating structural dynamics problems during the design phase of the shuttle program. The 1/8-scale model program was developed to explore the adequacy of available analytical modeling technology and to provide the means for investigating problems which are more readily treated experimentally. The basic objectives of the 1/8-scale model program are: (1) to provide early verification of analytical modeling procedures on a shuttle-like structure, (2) to demonstrate important vehicle dynamic characteristics of a typical shuttle design, (3) to disclose any previously unanticipated structural dynamic characteristics, and (4) to provide for development and demonstration of cost effective prototype testing procedures.

ISABELLE: a proposal for construction of a proton--proton storage accelerator facility

International Nuclear Information System (INIS)

1976-05-01

The construction of an Intersecting Storage Accelerator Facility (ISA or ISABELLE) at Brookhaven National Laboratory is proposed. ISABELLE will permit the exploration of proton-proton collisions at center-of-mass energies continuously variable from 60 to 400 GeV and with luminosities of 10 32 to 10 33 cm -2 sec -1 over the entire range. An overview of the physics potential of this machine is given, covering the production of charged and neutral intermediate vector bosons, the hadron production at high transverse momentum, searches for new, massive particles, and the energy dependence of the strong interactions. The facility consists of two interlaced rings of superconducting magnets in a common tunnel about 3 km in circumference. The proton beams will collide at eight intersection regions where particle detectors will be arranged for studying the collision processes. Protons of approximately 30 GeV from the AGS will be accumulated to obtain the design current of 10A prior to acceleration to final energy. The design and performance of existing full-size superconducting dipoles and quadrupoles is described. The conceptual design of the accelerator systems and the conventional structures and buildings is presented. A preliminary cost estimate and construction schedule are given. Possible future options such as proton-antiproton, proton-deuteron and electron-proton collisions are discussed

SU-E-J-63: Feasibility Study of Proton Digital Tomosynthesis in Proton Beam Therapy.

Science.gov (United States)

Min, B; Kwak, J; Lee, J; Cho, S; Park, S; Yoo, S; Chung, K; Cho, S; Lim, Y; Shin, D; Lee, S; Kim, J

2012-06-01

We investigated the feasibility of proton tomosynthesis as daily positioning of patients and compared the results with photon tomosynthesis as an alternative to conventional portal imaging or on-board cone-beam computed tomography. Dedicated photon-like proton beam using the passively scattered proton beams by the cyclotron was generated for proton imaging. The eleven projections were acquired over 30 degree with 3 degree increment in order to investigate the performance of proton tomosynthesis. The cylinder blocks and resolution phantom were used to evaluate imaging performance. Resolution phantom of a cylinder of diameter 12 cm was used to investigate the reconstructed imaging characteristics. Electron density cylinder blocks with diameter of 28 mm and height of 70 mm were employed to assess the imaging quality. The solid water, breast, bone, adipose, lung, muscle, and liver, which were tissue equivalent inserts, were positioned around the resolution phantom. The images were reconstructed by projection onto convex sets (POCS) algorithm and total variation minimization (TVM) methods. The Gafchromic EBT films were utilized for measuring the photon-like proton beams as a proton detector. In addition, the photon tomosynthesis images were obtained for a comparison with proton tomosynthesis images. The same angular sampling data were acquired for both proton and photon tomosynthesis. In the resolution phantom image obtained proton tomosynthesis, down to 1.6 mm diameter rods were resolved visually, although the separation between adjacent rods was less distinct. In contrast, down to 1.2 mm diameter rods were resolved visually in the reconstructed image obtained photon tomosynthesis. Both proton and photon tomosynthesis images were similar in intensities of different density blocks. Our results demonstrated that proton tomosynthesis could make it possible to provide comparable tomography imaging to photon tomosynthesis for positioning as determined by manual registration

Proton-proton elastic scattering at ultrahigh energies

Energy Technology Data Exchange (ETDEWEB)

Saleem, M.; Shaukat, M.A.; Fazal-e-Aleem (University of the Punjab, Lahore (Pakistan). Dept. of Physics)

1981-05-30

Recent experimental results on proton-proton elastic scattering at high energies are discussed in the context of the comments by Chou and Yang. There does not appear to be any tendency that the experimental results would agree with the predictions of the geometrical model even at ultrahigh energies. The angular distribution structure as described by using the dipole pomeron is consistent with the experimental data at presently available high energies and predicts results quite different from the geometrical model.

Two proton decay in 12O

International Nuclear Information System (INIS)

Kumawat, M.; Singh, U.K.; Jain, S.K.; Saxena, G.; Kaushik, M.; Aggarwal, Mamta

2017-01-01

Two-proton radioactivity was observed experimentally in the decay of 45 Fe, 54 Zn and 48 Ni. From then many theoretical studies of one and two-proton radioactivity have been carried out within the framework of different models including RMF+BCS approach for medium mass region. Towards light mass region proton-proton correlations were observed in two-proton decay of 19 Mg and 16 Ne. Recently, different mechanism of two-proton emission from proton-rich nuclei 23 Al and 22 Mg has been investigated and transition from direct to sequential two-proton decay in sd shell nuclei is observed. Encouraged with these recent studies of two proton emission in light mass nuclei, we have applied our RMF+BCS approach for the study of two proton emission in light mass region and in this paper we present our result of two proton emission in 12 O

Moving protons with pendant amines: proton mobility in a nickel catalyst for oxidation of hydrogen.

Science.gov (United States)

O'Hagan, Molly; Shaw, Wendy J; Raugei, Simone; Chen, Shentan; Yang, Jenny Y; Kilgore, Uriah J; DuBois, Daniel L; Bullock, R Morris

2011-09-14

Proton transport is ubiquitous in chemical and biological processes, including the reduction of dioxygen to water, the reduction of CO(2) to formate, and the production/oxidation of hydrogen. In this work we describe intramolecular proton transfer between Ni and positioned pendant amines for the hydrogen oxidation electrocatalyst [Ni(P(Cy)(2)N(Bn)(2)H)(2)](2+) (P(Cy)(2)N(Bn)(2) = 1,5-dibenzyl-3,7-dicyclohexyl-1,5-diaza-3,7-diphosphacyclooctane). Rate constants are determined by variable-temperature one-dimensional NMR techniques and two-dimensional EXSY experiments. Computational studies provide insight into the details of the proton movement and energetics of these complexes. Intramolecular proton exchange processes are observed for two of the three experimentally observable isomers of the doubly protonated Ni(0) complex, [Ni(P(Cy)(2)N(Bn)(2)H)(2)](2+), which have N-H bonds but no Ni-H bonds. For these two isomers, with pendant amines positioned endo to the Ni, the rate constants for proton exchange range from 10(4) to 10(5) s(-1) at 25 °C, depending on isomer and solvent. No exchange is observed for protons on pendant amines positioned exo to the Ni. Analysis of the exchange as a function of temperature provides a barrier for proton exchange of ΔG(‡) = 11-12 kcal/mol for both isomers, with little dependence on solvent. Density functional theory calculations and molecular dynamics simulations support the experimental observations, suggesting metal-mediated intramolecular proton transfers between nitrogen atoms, with chair-to-boat isomerizations as the rate-limiting steps. Because of the fast rate of proton movement, this catalyst may be considered a metal center surrounded by a cloud of exchanging protons. The high intramolecular proton mobility provides information directly pertinent to the ability of pendant amines to accelerate proton transfers during catalysis of hydrogen oxidation. These results may also have broader implications for proton movement in

Proton Radiography with CR-39 by Using the Protons from High Power Femto-second Laser System

International Nuclear Information System (INIS)

Choi, Chang Il; Lee, Dong Hoon; Kang, Byoung Hwi; Kim, Yong Kyun; Choi, Il Woo; Ko, Do Kyeong; Lee, Jong Min

2008-01-01

Proton radiography techniques are useful to obtain a high quality image of a thin object, because protons travel straight in matter. Generation of the high energy proton using conventional accelerator costs high and requires large accelerating facility. But proton radiography using high power femto-second(10-15 second) laser has been interested, because it can generate high energy protons at lower price than the conventional accelerator like a cyclotron. For this study, we used the CR-39 SSNTD (Solid State Nuclear Track Detector) as the proton radiography screen. Commonly, CR-39 is used to detect the tracks of energetic charged particles. Incident energetic charged particles left latent tracks in the CR-39, in the form of broken molecular chains and free radicals. These latent tracks show high chemical reactivity. After chemical etching with the caustic alkali solution such as NaOH or KOH, tracks are appeared to forms of hole. If protons with various energies enter the two targets with another thickness, number of protons passed through the target per unit area is different each other. Using this feature of protons, we can a proton radiographic image with CR-39. We studied proton radiography with CR-39 by using energetic protons from high power femto-second laser and evaluated potentiality of femto-second laser as new energetic proton generator for radiography

Proton permeation of lipid bilayers.

Science.gov (United States)

Deamer, D W

1987-10-01

Proton permeation of the lipid bilayer barrier has two unique features. First, permeability coefficients measured at neutral pH ranges are six to seven orders of magnitude greater than expected from knowledge of other monovalent cations. Second, proton conductance across planar lipid bilayers varies at most by a factor of 10 when pH is varied from near 1 to near 11. Two mechanisms have been proposed to account for this anomalous behavior: proton conductance related to contaminants of lipid bilayers, and proton translocation along transient hydrogen-bonded chains (tHBC) of associated water molecules in the membrane. The weight of evidence suggests that trace contaminants may contribute to proton conductance across planar lipid membranes at certain pH ranges, but cannot account for the anomalous proton flux in liposome systems. Two new results will be reported here which were designed to test the tHBC model. These include measurements of relative proton/potassium permeability in the gramicidin channel, and plots of proton flux against the magnitude of pH gradients. (1) The relative permeabilities of protons and potassium through the gramicidin channel, which contains a single strand of hydrogen-bonded water molecules, were found to differ by at least four orders of magnitude when measured at neutral pH ranges. This result demonstrates that a hydrogen-bonded chain of water molecules can provide substantial discrimination between protons and other cations. It was also possible to calculate that if approximately 7% of bilayer water was present in a transient configuration similar to that of the gramicidin channel, it could account for the measured proton flux. (2) The plot of proton conductance against pH gradient across liposome membranes was superlinear, a result that is consistent with one of three alternative tHBC models for proton conductance described by Nagle elsewhere in this volume.

Space Shuttle dosimetry measurements with RME-III

International Nuclear Information System (INIS)

Hardy, K.A.; Golightly, M.J.; Hardy, A.C.; Atwell, W.; Quam, W.

1991-10-01

A description of the radiation monitoring equipment (RME-III) dosimetry instrument and the results obtained from six Space Shuttle flights are presented. The RME-III is a self-contained, active (real-time), portable dosimeter system developed for the USAF and adapted for utilization in measuring the ionizing radiation environment on the Space Shuttle. This instrument was developed to incorporate the capabilities of two earlier radiation instruments into a single unit and to minimize crew interaction times with longer battery life and expanded memory capacity. Flight data has demonstrated that the RME-III can be used to accurately assess dose from various sources of exposure, such as that encountered in the complex radiation environment of space

Proton beam characterization by proton-induced acoustic emission: simulation studies

International Nuclear Information System (INIS)

Jones, K C; Witztum, A; Avery, S; Sehgal, C M

2014-01-01

Due to their Bragg peak, proton beams are capable of delivering a targeted dose of radiation to a narrow volume, but range uncertainties currently limit their accuracy. One promising beam characterization technique, protoacoustic range verification, measures the acoustic emission generated by the proton beam. We simulated the pressure waves generated by proton radiation passing through water. We observed that the proton-induced acoustic signal consists of two peaks, labeled α and γ, with two originating sources. The α acoustic peak is generated by the pre-Bragg peak heated region whereas the source of the γ acoustic peak is the proton Bragg peak. The arrival time of the α and γ peaks at a transducer reveals the distance from the beam propagation axis and Bragg peak center, respectively. The maximum pressure is not observed directly above the Bragg peak due to interference of the acoustic signals. Range verification based on the arrival times is shown to be more effective than determining the Bragg peak position based on pressure amplitudes. The temporal width of the α and γ peaks are linearly proportional to the beam diameter and Bragg peak width, respectively. The temporal separation between compression and rarefaction peaks is proportional to the spill time width. The pressure wave expected from a spread out Bragg peak dose is characterized. The simulations also show that acoustic monitoring can verify the proton beam dose distribution and range by characterizing the Bragg peak position to within ∼1 mm. (paper)

Generalized z-scaling in proton-proton collisions at high energies

International Nuclear Information System (INIS)

Zborovsky, I.; Tokarev, M.

2006-01-01

New generalization of z-scaling in inclusive particle production is proposed. The scaling variable z is a fractal measure which depends on kinematical characteristics of the underlying subprocess expressed in terms of the momentum fractions x 1 and x 2 of the incoming protons. In the generalized approach, the x 1 and x 2 are functions of the momentum fractions y a and y b of the scattered and recoil constituents carried out by the inclusive particle and recoil object, respectively. The scaling function ψ(z) for charged and identified hadrons produced in proton-proton collisions is constructed. The fractal dimensions and heat capacity of the produced medium entering definition of the z are established to obtain energy, angular and multiplicity independence of the ψ(z). The scheme allows unique description of data on inclusive cross sections of charged particles, pions, kaons, antiprotons, and lambdas at high energies. The obtained results are of interest to use z-scaling as a tool for searching for new physics phenomena of particle production in high transverse momentum and high multiplicity region at the proton-proton colliders RHIC and LHC

Proton-proton, anti-proton-anti-proton, proton-anti-proton correlations in Au+Au collisions measured by STAR at RHIC

International Nuclear Information System (INIS)

Gos, H.P.

2007-01-01

The analysis of two-particle correlations provides a powerful tool to study the properties of hot and dense matter created in heavy-ion collisions at ultra-relativistic energies. Applied to identical and non-identical hadron pairs, it makes the study of space-time evolution of the source in femtoscopic scale possible. Baryon femtoscopy allows extraction of the radii of produced sources which can be compared to those deduced from identical pion studies, providing complete information about the source characteristics. In this paper we present the correlation functions obtained for identical and non-identical baryon pairs of protons and anti-protons. The data were collected recently in Au+Au collisions at √(s NN )=62 GeV and √(s NN )=200 GeV by the STAR detector at the RHIC accelerator. We introduce corrections to the baryon-baryon correlations taking into account: residual correlations from weak decays, particle identification probability and the fraction of primary baryons. Finally we compare our results to theoretical predictions. (orig.)

Solar proton fluxes since 1956

International Nuclear Information System (INIS)

Reedy, R.C.

1977-01-01

The fluxes of protons emitted during solar flares since 1956 were evaluated. The depth-versus-activity profiles of 56 Co in several lunar rocks are consistent with the solar-proton fluxes detected by experiments on several satellites. Only about 20% of the solar-proton-induced activities of 22 Na and 55 Fe in lunar rocks from early Apollo missions were produced by protons emitted from the sun during solar cycle 20 (1965--1975). The depth-versus-activity data for these radionuclides in several lunar rocks were used to determine the fluxes of protons during solar cycle 19 (1954--1964). The average proton fluxes for cycle 19 are about five times those for both the last million years and for cycle 20. These solar-proton flux variations correlate with changes in sunspot activity

External proton and Li beams; Haces externos de protones y litios

Energy Technology Data Exchange (ETDEWEB)

Schuff, Juan A; Burlon, Alejandro A; Debray, Mario E; Kesque, Jose M; Kreiner, Andres J; Stoliar, Pablo A; Naab, Fabian; Ozafran, Mabel J; Vazquez, Monica E [Comision Nacional de Energia Atomica, General San Martin (Argentina). Dept. de Fisica; Policastro, Lucia L; Duran, Hebe; Molinari, Beatriz L; O' Connor, Silvia E; Saint-Martin, Maria L.G.; Palmieri, Monica; Bernaola, Omar A; Opezzo, Oscar J [Comision Nacional de Energia Atomica, General San Martin (Argentina). Dept. de Radiobiologia; Mazal, A; Favaudon, F; Henry, Y [Institut Curie, 75 - Paris (France); Perez de la Hoz, A.; Somacal, Hector; Valda, Alejandro; Canevas, S; Ruffolo, M; Tasat, D R [Universidad Nacional de General San Martin, Villa Ballester (Argentina). Escuela de Ciencia y Tecnologia; Davidson, Miguel; Davidson, Jorge [Buenos Aires Univ. (Argentina). Dept. de Fisica; Delacroix, S; Nauraye, C; Brune, E; Gautier, C; Habrand, J L [Centre de Protontherapie, 91 - Orsay (France); Muhlmann, M C [Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires (Argentina)

2000-07-01

In the frame of a feasibility study to introduce proton therapy in Argentina in a collaborative agreement between the Physics and Radiobiology Departments of the National Atomic Energy Commission or Argentina and the Centre de Protontherapie de Orsay, France, external proton and Li beams were produced at the TANDAR accelerator in Buenos Aires. The specific aim of this work was to start radiobiology studies on cell cultures and small laboratory animals. In particular we seek to determine here the relative biological effectiveness, RBE, for proton and Li beams as a function of energy for different tumor and normal cell lines. The 24 MeV proton beam was diffused using a 25 {mu}m gold foil and extracted through a Kapton window to obtain a homogeneous field (constant to 95%) of about 7 cm in diameter. Measurements were carried out with quasi-monoenergetic beams (of 20.2 {+-} 0.07 MeV, 2.9 {+-} 0.10 MeV y 1.5 {+-} 0.1 MeV for protons and 21.4 {+-} 0.4 MeV for Lithium). Proton fluence and Bragg peaks were measured. The dose delivered in each case was monitored on-line with a calibrated transmission ionization chamber. Three cell lines PDV, PDVC 57 and V 79 (as a reference) were irradiated with {gamma}-rays, proton and lithium beams with linear energy transfer (LET) from 2 to 100 keV/{mu}m. RBE values in the range of 1.2-5.9 were obtained. In addition preliminary studies on chromosomal aberrations and viability of alveolar macrophages were carried out. (author)

Proton-proton elastic scattering at ultrahigh energies

International Nuclear Information System (INIS)

Saleem, M.; Shaukat, M.A.; Fazal-e-Aleem

1981-01-01

Recent experimental results on proton-proton elastic scattering at high energies are discussed in the context of the comments by Chou and Yang. There does not appear to be any tendency that the experimental results would agree with the predictions of the geometrical model even at ultrahigh energies. The angular distribution structure as described by using the dipole pomeron is consistent with the experimental data at presently available high energies and predicts results quite different from the geometrical model. (author)

Assembling and supplying the ISS the space shuttle fulfills its mission

CERN Document Server

Shayler, David J

2017-01-01

The creation and utilization of the International Space Station (ISS) is a milestone in space exploration. But without the Space Shuttle, it would have remained an impossible dream. Assembling and Supplying the ISS is the story of how, between 1998 and 2011, the Shuttle became the platform which enabled the construction and continued operation of the primary scientific research facility in Earth orbit. Fulfilling an objective it had been designed to complete decades before, 37 Shuttle missions carried the majority of the hardware needed to build the ISS and then acted as a ferry and supply train for early resident crews to the station. Building upon the decades of development and experience described in the companion volume Linking the Space Shuttle and Space Stations: Early Docking Technologies from Concept to Implementation, this book explores • a purpose-built hardware processing facility • challenging spacewalking objectives • extensive robotic operations • undocking a unmanned orbiter The experie...

To orbit and back again how the space shuttle flew in space

CERN Document Server

Sivolella, Davide

2014-01-01

The question may be simple, but the answer is not as easy to give. This book describes the structures and systems used each time the Shuttle was launched, and then follows an imaginary mission, explaining how those structures and systems were used in orbital operations and the return to Earth. Details of how anomalous events were dealt with on individual missions are also provided, as are the recollections of those who built and flew the Shuttle. Highly illustrated with many diagrams, photographs and technical drawings, To Orbit and Back Again • focuses on the engineering aspects of the Shuttle • describes the systems and subsystems in clear, non-technical terms • brings to the fore the design work behind the Space Shuttle and the mission itself.    .

On Distributions of Emission Sources and Speed-of-Sound in Proton-Proton (Proton-Antiproton Collisions

Directory of Open Access Journals (Sweden)

Li-Na Gao

2015-01-01

Full Text Available The revised (three-source Landau hydrodynamic model is used in this paper to study the (pseudorapidity distributions of charged particles produced in proton-proton and proton-antiproton collisions at high energies. The central source is assumed to contribute with a Gaussian function which covers the rapidity distribution region as wide as possible. The target and projectile sources are assumed to emit isotropically particles in their respective rest frames. The model calculations obtained with a Monte Carlo method are fitted to the experimental data over an energy range from 0.2 to 13 TeV. The values of the squared speed-of-sound parameter in different collisions are then extracted from the width of the rapidity distributions.

Molecular mechanism of voltage sensing in voltage-gated proton channels

Science.gov (United States)

Rebolledo, Santiago; Perez, Marta E.

2013-01-01

Voltage-gated proton (Hv) channels play an essential role in phagocytic cells by generating a hyperpolarizing proton current that electrically compensates for the depolarizing current generated by the NADPH oxidase during the respiratory burst, thereby ensuring a sustained production of reactive oxygen species by the NADPH oxidase in phagocytes to neutralize engulfed bacteria. Despite the importance of the voltage-dependent Hv current, it is at present unclear which residues in Hv channels are responsible for the voltage activation. Here we show that individual neutralizations of three charged residues in the fourth transmembrane domain, S4, all reduce the voltage dependence of activation. In addition, we show that the middle S4 charged residue moves from a position accessible from the cytosolic solution to a position accessible from the extracellular solution, suggesting that this residue moves across most of the membrane electric field during voltage activation of Hv channels. Our results show for the first time that the charge movement of these three S4 charges accounts for almost all of the measured gating charge in Hv channels. PMID:23401575

Evaluation of the Induced Activity in Air by the External Proton Beam in the Target Room of the Proton Accelerator Facility of Proton Engineering Frontier Project

International Nuclear Information System (INIS)

Lee, Cheol Woo; Lee, Young Ouk; Cho, Young Sik; Ahn, So Hyun

2007-01-01

One of the radiological concerns is the worker's exposure level and the concentration of the radionuclides in the air after shutdown, for the safety analysis on the proton accelerator facility. Although, the primary radiation source is the protons accelerated up to design value, all of the radio-nuclide is produced from the secondary neutron and photon induced reaction in air. Because, the protons don't penetrate the acceleration equipment like the DTL tank wall or BTL wall, secondary neutrons or photons are only in the air in the accelerator tunnel building because of the short range of the proton in the materials. But, for the case of the target rooms, external proton beams are occasionally used in the various experiments. When these external proton beams travel through air from the end of the beam transport line to the target, they interact directly with air and produce activation products from the proton induced reaction. The external proton beam will be used in the target rooms in the accelerator facility of the Proton Accelerator Frontier Project (PEFP). In this study, interaction characteristics of the external proton beam with air and induced activity in air from the direct interaction of the proton beam were evaluated

Space Shuttle Status News Conference

Science.gov (United States)

2005-01-01

Richard Gilbech, External Tank "Tiger Team" Lead, begins this space shuttle news conference with detailing the two major objectives of the team. The objectives include: 1) Finding the root cause of the foam loss on STS-114; and 2) Near and long term improvements for the external tank. Wayne Hale, Space Shuttle Program Manager, presents a chart to explain the external tank foam loss during STS-114. He gives a possible launch date for STS-121 after there has been a repair to the foam on the External Tank. He further discusses the changes that need to be made to the surrounding areas of the plant in New Orleans, due to Hurricane Katrina. Bill Gerstemaier, NASA Associate Administrator for Space Operations, elaborates on the testing of the external tank foam loss. The discussion ends with questions from the news media about a fix for the foam, replacement of the tiles, foam loss avoidance, the root cause of foam loss and a possible date for a new external tank to be shipped to NASA Kennedy Space Center.

Proton beam characterization in the experimental room of the Trento Proton Therapy facility

Science.gov (United States)

Tommasino, F.; Rovituso, M.; Fabiano, S.; Piffer, S.; Manea, C.; Lorentini, S.; Lanzone, S.; Wang, Z.; Pasini, M.; Burger, W. J.; La Tessa, C.; Scifoni, E.; Schwarz, M.; Durante, M.

2017-10-01

As proton therapy is becoming an established treatment methodology for cancer patients, the number of proton centres is gradually growing worldwide. The economical effort for building these facilities is motivated by the clinical aspects, but might be also supported by the potential relevance for the research community. Experiments with high-energy protons are needed not only for medical physics applications, but represent also an essential part of activities dedicated to detector development, space research, radiation hardness tests, as well as of fundamental research in nuclear and particle physics. Here we present the characterization of the beam line installed in the experimental room of the Trento Proton Therapy Centre (Italy). Measurements of beam spot size and envelope, range verification and proton flux were performed in the energy range between 70 and 228 MeV. Methods for reducing the proton flux from typical treatments values of 106-109 particles/s down to 101-105 particles/s were also investigated. These data confirm that a proton beam produced in a clinical centre build by a commercial company can be exploited for a broad spectrum of experimental activities. The results presented here will be used as a reference for future experiments.

Transverse Single-Spin Asymmetries in Proton-Proton Collisions at the AFTER@LHC Experiment

Directory of Open Access Journals (Sweden)

K. Kanazawa

2015-01-01

Full Text Available We present results for transverse single-spin asymmetries in proton-proton collisions at kinematics relevant for AFTER, a proposed fixed-target experiment at the Large Hadron Collider. These include predictions for pion, jet, and direct photon production from analytical formulas already available in the literature. We also discuss specific measurements that will benefit from the higher luminosity of AFTER, which could help resolve an almost 40-year puzzle of what causes transverse single-spin asymmetries in proton-proton collisions.

Launch Vehicle Demonstrator Using Shuttle Assets

Science.gov (United States)

Threet, Grady E., Jr.; Creech, Dennis M.; Philips, Alan D.; Water, Eric D.

2011-01-01

The Marshall Space Flight Center Advanced Concepts Office (ACO) has the leading role for NASA s preliminary conceptual launch vehicle design and performance analysis. Over the past several years the ACO Earth-to-Orbit Team has evaluated thousands of launch vehicle concept variations for a multitude of studies including agency-wide efforts such as the Exploration Systems Architecture Study (ESAS), Constellation, Heavy Lift Launch Vehicle (HLLV), Heavy Lift Propulsion Technology (HLPT), Human Exploration Framework Team (HEFT), and Space Launch System (SLS). NASA plans to continue human space exploration and space station utilization. Launch vehicles used for heavy lift cargo and crew will be needed. One of the current leading concepts for future heavy lift capability is an inline one and a half stage concept using solid rocket boosters (SRB) and based on current Shuttle technology and elements. Potentially, the quickest and most cost-effective path towards an operational vehicle of this configuration is to make use of a demonstrator vehicle fabricated from existing shuttle assets and relying upon the existing STS launch infrastructure. Such a demonstrator would yield valuable proof-of-concept data and would provide a working test platform allowing for validated systems integration. Using shuttle hardware such as existing RS-25D engines and partial MPS, propellant tanks derived from the External Tank (ET) design and tooling, and four-segment SRB s could reduce the associated upfront development costs and schedule when compared to a concept that would rely on new propulsion technology and engine designs. There are potentially several other additional benefits to this demonstrator concept. Since a concept of this type would be based on man-rated flight proven hardware components, this demonstrator has the potential to evolve into the first iteration of heavy lift crew or cargo and serve as a baseline for block upgrades. This vehicle could also serve as a demonstration

The EDDA experiment: proton-proton elastic scattering excitation functions at intermediate energies

International Nuclear Information System (INIS)

Hinterberher, F.

1996-01-01

The EDDA experiment is designed to provide a high precision measurement of proton-proton elastic scattering excitation functions ranging from 0.5 to 2.5 GeV of (lab) incident kinetic energy. It is an internal target experiment utilizing the proton beam of the cooler synchrotron COSY operated by KFA Juelich. The excitation functions are measured during the acceleration ramp of COSY. (author)

Proton storage rings

International Nuclear Information System (INIS)

Rau, R.R.

1978-04-01

A discussion is given of proton storage ring beam dynamic characteristics. Topics considered include: (1) beam energy; (2) beam luminosity; (3) limits on beam current; (4) beam site; (5) crossing angle; (6) beam--beam interaction; (7) longitudinal instability; (8) effects of scattering processes; (9) beam production; and (10) high magnetic fields. Much of the discussion is related to the design parameters of ISABELLE, a 400 x 400 GeV proton---proton intersecting storage accelerator to be built at Brookhaven National Laboratory

Shuttle Experimental Radar for Geological Exploration (SERGE) project: Field work relating to the Shuttle Experimental Radar A (SIR-A) in Brazil (phase 2)

Science.gov (United States)

Balieiro, M. G.; Martini, P. R.; Dossantos, J. R.; Demattos, J. T.

1984-01-01

The ground observations undertaken over the northern position of Minas Gerais State, and part of Distrito Federal from 7 to 12 December 1982, along the Space Shuttle 2 flying orbit 22 of November 1981 are described. Field data related mostly with lithology, geological structures and forest cover, and specific geomorphological and pedological aspects were collected. Ground data are applied to evaluate the SIR-A Experiment, developed in the Space Shuttle-2 mission for natural resources mapping and prospecting.

Space shuttle operations integration plan

Science.gov (United States)

1975-01-01

The Operations Integration Plan is presented, which is to provide functional definition of the activities necessary to develop and integrate shuttle operating plans and facilities to support flight, flight control, and operations. It identifies the major tasks, the organizations responsible, their interrelationships, the sequence of activities and interfaces, and the resultant products related to operations integration.

The measurement of proton stopping power using proton-cone-beam computed tomography

International Nuclear Information System (INIS)

Zygmanski, P.; Rabin, M.S.Z.; Gall, K.P.; Rosenthal, S.J.

2000-01-01

A cone-beam computed tomography (CT) system utilizing a proton beam has been developed and tested. The cone beam is produced by scattering a 160 MeV proton beam with a modifier that results in a signal in the detector system, which decreases monotonically with depth in the medium. The detector system consists of a Gd 2 O 2 S:Tb intensifying screen viewed by a cooled CCD camera. The Feldkamp-Davis-Kress cone-beam reconstruction algorithm is applied to the projection data to obtain the CT voxel data representing proton stopping power. The system described is capable of reconstructing data over a 16x16x16cm 3 volume into 512x512x512 voxels. A spatial and contrast resolution phantom was scanned to determine the performance of the system. Spatial resolution is significantly degraded by multiple Coulomb scattering effects. Comparison of the reconstructed proton CT values with x-ray CT derived proton stopping powers shows that there may be some advantage to obtaining stopping powers directly with proton CT. The system described suggests a possible practical method of obtaining this measurement in vivo. (author)

Proton position near QB and coupling of electron and proton transfer in photosynthesis

International Nuclear Information System (INIS)

Belousov, R V; Poltev, S V; Kukushkin, A K

2003-01-01

We have calculated the energy levels and wavefunctions of a proton in a histidine (His)-plastoquinone (PQ) system in the reaction centre (RC) of photosystem 2 of higher plants and the RC of purple bacteria for different redox states of PQ Q B . For oxidized Q B , the proton is located near His. For once-reduced PQ, it is positioned in the middle between the nitrogen of His and the oxygen of PQ. For twofold-reduced PQ, the proton is localized near the oxygen of PQ. Using the values of total energy of the system in these states, we have also estimated the frequency of proton oscillations. On the basis of these results we propose a hypothesis about the coupling of electron-proton transfer

Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes

NARCIS (Netherlands)

Pettersen, H. E. S.; Alme, J.; Biegun, A.; van den Brink, A.; Chaar, M.; Fehlker, D.; Meric, I.; Odland, O. H.; Peitzmann, T.; Rocco, E.; Ullaland, K.; Wang, H.; Yang, S.; Zhang, C.; Rohrich, D.

2017-01-01

Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue introduces range uncertainties of the order of 2-3% of the

[Why proton therapy? And how?

Science.gov (United States)

Thariat, Juliette; Habrand, Jean Louis; Lesueur, Paul; Chaikh, Abdulhamid; Kammerer, Emmanuel; Lecomte, Delphine; Batalla, Alain; Balosso, Jacques; Tessonnier, Thomas

2018-03-01

Proton therapy is a radiotherapy, based on the use of protons, charged subatomic particles that stop at a given depth depending on their initial energy (pristine Bragg peak), avoiding any output beam, unlike the photons used in most of the other modalities of radiotherapy. Proton therapy has been used for 60 years, but has only become ubiquitous in the last decade because of recent major advances in particle accelerator technology. This article reviews the history of clinical implementation of protons, the nature of the technological advances that now allows its expansion at a lower cost. It also addresses the technical and physical specificities of proton therapy and the clinical situations for which proton therapy may be relevant but requires evidence. Different proton therapy techniques are possible. These are explained in terms of their clinical potential by explaining the current terminology (such as cyclotrons, synchrotrons or synchrocyclotrons, using superconducting magnets, fixed line or arm rotary with passive diffusion delivery or active by scanning) in basic words. The requirements associated with proton therapy are increased due to the precision of the depth dose deposit. The learning curve of proton therapy requires that clinical indications be prioritized according to their associated uncertainties (such as range uncertainties and movement in lung tumors). Many clinical indications potentially fall under proton therapy ultimately. Clinical strategies are explained in a paralleled manuscript. Copyright © 2018 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

PROTON MICROSCOPY AT FAIR

International Nuclear Information System (INIS)

Merrill, F. E.; Mariam, F. G.; Golubev, A. A.; Turtikov, V. I.; Varentsov, D.

2009-01-01

Proton radiography was invented in the 1990's at Los Alamos National Laboratory (LANL) as a diagnostic to study dynamic material properties under extreme pressures, strain and strain rate. Since this time hundreds of dynamic proton radiography experiments have been performed at LANL and a facility has been commissioned at the Institute for Theoretical and Experimental Physics (ITEP) in Russia for similar applications in dynamic material studies. Recently an international effort has investigated a new proton radiography capability for the study of dynamic material properties at the Facility for Anti-proton and Ion Research (FAIR) located in Darmstadt, Germany. This new Proton microscope for FAIR(PRIOR) will provide radiographic imaging of dynamic systems with unprecedented spatial, temporal and density resolution, resulting in a window for understanding dynamic material properties at new length scales. It is also proposed to install the PRIOR system at the GSI Helmholtzzentrum fuer Schwerionenforschung before installation at FAIR for dynamic experiments with different drivers including high explosives, pulsed power and lasers. The design of the proton microscope and expected radiographic performance is presented.

Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes

NARCIS (Netherlands)

Pettersen, H. E.S.; Alme, J.; Biegun, A.; van den Brink, A.; Chaar, M.; Fehlker, D.; Meric, I.; Odland, O. H.; Peitzmann, T.; Rocco, E.; Ullaland, K.; Wang, H.; Yang, S.; Zhang, C.; Röhrich, D.

2017-01-01

Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue introduces range uncertainties of the order of 2–3% of the

Neutron spectrum and dose-equivalent in shuttle flights during solar maximum

Energy Technology Data Exchange (ETDEWEB)

Keith, J E; Badhwar, G D; Lindstrom, D J [National Aeronautics and Space Administration, Houston, TX (United States). Lyndon B. Johnson Space Center

1992-01-01

This paper presents unambiguous measurements of the spectrum of neutrons found in spacecraft during spaceflight. The neutron spectrum was measured from thermal energies to about 10 MeV using a completely passive system of metal foils as neutron detectors. These foils were exposed to the neutron flux bare, covered by thermal neutron absorbers (Gd) and inside moderators (Bonner spheres). This set of detectors was flown on three U.S. Space Shuttle flights, STS-28, STS-36 and STS-31, during the solar maximum. We show that the measurements of the radioactivity of these foils lead to a differential neutron energy spectrum in all three flights that can be represented by a power law, J(E){approx equal}E{sup -0.765} neutrons cm{sup -2} day {sup -1} MeV{sup -1}. We also show that the measurements are even better represented by a linear combination of the terrestrial neutron albedo and a spectrum of neutrons locally produced in a aluminium by protons, computed by a previous author. We use both approximations to the neutron spectrum to produce a worst case and most probable case for the neutron spectra and the resulting dose-equivalents, computed using ICRP-51 neutron fluence-dose conversion tables. We compare these to the skin dose-equivalents due to charged particles during the same flights. (author).

First-ever evening public engine test of a Space Shuttle Main Engine

Science.gov (United States)

2001-01-01

Thousands of people watch the first-ever evening public engine test of a Space Shuttle Main Engine at NASA's John C. Stennis Space Center. The spectacular test marked Stennis Space Center's 20th anniversary celebration of the first Space Shuttle mission.

Proton radioactivity: the case for 53m Co proton-emitter isomer

International Nuclear Information System (INIS)

Tavares, O.A.P.; Medeiros, E.L.

2010-01-01

The partial proton emission half-life for 53m Co unstable isomer is re-examined in the framework of a semiempirical model based on tunneling through a Coulomb-plus centrifugal- plus-overlapping potential barrier within the spherical nucleus approximation. It is shown that the known measured half-life value of 17 s is compatible with a large prolate shape for 53m Co proton emitter and a high angular momentum ι = 11 assigned to the proton transition to the ground-state of 52 Fe. (author)

Ambiguities of the phase analysis of the proton-proton scattering amplitude

International Nuclear Information System (INIS)

Grebenyuk, O.G.; Shklyarevskij, G.M.

1980-01-01

Ambiguities of the phase analysis of the proton-proton scattering amplitude are analysed. It is shown that for five measurements of polarization parameters sets there are ambiguities similar to the Gersten ambiguities in the phase analysis of πN scattering. A problem on additional experiments needed to eliminate these ambiguities is investigated. It is shown that for this purpose it suffices to measure three total cross sections with polarized and nonpolarized protons, thus determining the imaginary parts of amplitudes at THETA=0 and polarization parameters

Study on patient-induced radioactivity during proton treatment in hengjian proton medical facility.

Science.gov (United States)

Wu, Qingbiao; Wang, Qingbin; Liang, Tianjiao; Zhang, Gang; Ma, Yinglin; Chen, Yu; Ye, Rong; Liu, Qiongyao; Wang, Yufei; Wang, Huaibao

2016-09-01

At present, increasingly more proton medical facilities have been established globally for better curative effect and less side effect in tumor treatment. Compared with electron and photon, proton delivers more energy and dose at its end of range (Bragg peak), and has less lateral scattering for its much larger mass. However, proton is much easier to produce neutron and induced radioactivity, which makes radiation protection for proton accelerators more difficult than for electron accelerators. This study focuses on the problem of patient-induced radioactivity during proton treatment, which has been ignored for years. However, we confirmed it is a vital factor for radiation protection to both patient escort and positioning technician, by FLUKA's simulation and activation formula calculation of Hengjian Proton Medical Facility (HJPMF), whose energy ranges from 130 to 230MeV. Furthermore, new formulas for calculating the activity buildup process of periodic irradiation were derived and used to study the relationship between saturation degree and half-life of nuclides. Finally, suggestions are put forward to lessen the radiation hazard from patient-induced radioactivity. Copyright © 2016 Elsevier Ltd. All rights reserved.

Experimental determination of the complete spin structure for anti-proton + proton -> anti-\\Lambda + \\Lambda at anti-proton beam momentum of 1.637 GeV/c

CERN Document Server

Paschke, K.D.; Berdoz, A.; Franklin, G.B.; Khaustov, P.; Meyer, C.A.; Bradtke, C.; Gehring, R.; Goertz, S.; Harmsen, J.; Meier, A.; Meyer, W.; Radtke, E.; Reicherz, G.; Dutz, H.; Pluckthun, M.; Schoch, B.; Dennert, H.; Eyrich, W.; Hauffe, J.; Metzger, A.; Moosburger, M.; Stinzing, F.; Wirth, St.; Fischer, H.; Franz, J.; Heinsius, F.H.; Kriegler, E.; Schmitt, H.; Bunker, B.; Hertzog, D.; Jones, T.; Tayloe, R.; Broders, R.; Geyer, R.; Kilian, K.; Oelert, W.; Rohrich, K.; Sachs, K.; Sefzick, T.; Bassalleck, B.; Eilerts, S.; Fields, D.E.; Kingsberry, P.; Lowe, J.; Stotzer, R.; Johansson, T.; Pomp, S.; Wirth, St.

2006-01-01

The reaction anti-proton + proton -> anti-\\Lambda + \\Lambda -> anti-proton + \\pi^+ + proton + \\pi^- has been measured with high statistics at anti-proton beam momentum of 1.637 GeV/c. The use of a transversely-polarized frozen-spin target combined with the self-analyzing property of \\Lambda/anti-\\Lambda decay allows access to unprecedented information on the spin structure of the interaction. The most general spin-scattering matrix can be written in terms of eleven real parameters for each bin of scattering angle, each of these parameters is determined with reasonable precision. From these results all conceivable spin-correlations are determined with inherent self-consistency. Good agreement is found with the few previously existing measurements of spin observables in anti-proton + proton -> anti-\\Lambda + \\Lambda near this energy. Existing theoretical models do not give good predictions for those spin-observables that had not been previously measured.

Hydroxy protons as structural probes to reveal hydrogen bonding properties of polyols in aqueous solution by NMR spectroscopy

Science.gov (United States)

Oruc, Gizem; Varnali, Tereza; Bekiroglu, Somer

2018-05-01

The solution properties of ethylene glycol (ethane-1,2-diol), glycerol (propane-1,2,3-triol), erythritol ((2R,3S)-butane-1,2,3,4-tetraol), D-xylitol ((2R,3r,4S)-pentane-1,2,3,4,5-pentaol), D-mannitol ((2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol), and D-sorbitol ((2S,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol), constituting a subgroup of polyalcohols/polyols of maximum six carbon atoms have been investigated using 1H NMR chemical shifts, coupling constants, temperature coefficients, and chemical exchange rates of hydroxy protons in aqueous medium. Relative within a molecule, minimum two-fold difference in rate of exchange values and higher temperature dependence of chemical shifts of the hydroxy protons on terminal carbon atoms confirm that sustainable hydrogen bonding interactions is accentuated for the hydroxyl groups on secondary carbons. Compared to the primary carbons i.e. terminal ones, the hydroxy protons on second and third carbon atoms exhibit much lower rate of exchange and smaller temperature coefficients, indicating that they are further involved in transient hydrogen bonding interactions. Scalar 3JOH,CH-couplings ranging between 3.9 and 7.2 Hz imply that the hydroxyl groups are practically in free rotation regime. Examination of the chemical shift differences with respect to the shift of glycol hydroxy proton reveals that the disparity between terminal and inner hydroxyl groups disclosed by the exchange rates and temperature coefficients is sustained with the exception of 0.003 and 0.053 ppm for O(3)H of mannitol and O(5)H of sorbitol respectively. The experimental findings have been augmented by quantum chemical calculations targeting theoretical NMR chemical shifts, as well as the conformational analysis of the structures.

Functional Requirements for Onboard Management of Space Shuttle Consumables. Volume 2

Science.gov (United States)

Graf, P. J.; Herwig, H. A.; Neel, L. W.

1973-01-01

This report documents the results of the study "Functional Requirements for Onboard Management of Space Shuttle Consumables." The study was conducted for the Mission Planning and Analysis Division of the NASA Lyndon B. Johnson Space Center, Houston, Texas, between 3 July 1972 and 16 November 1973. The overall study program objective was two-fold. The first objective was to define a generalized consumable management concept which is applicable to advanced spacecraft. The second objective was to develop a specific consumables management concept for the Space Shuttle vehicle and to generate the functional requirements for the onboard portion of that concept. Consumables management is the process of controlling or influencing the usage of expendable materials involved in vehicle subsystem operation. The report consists of two volumes. Volume I presents a description of the study activities related to general approaches for developing consumable management, concepts for advanced spacecraft applications, and functional requirements for a Shuttle consumables management concept. Volume II presents a detailed description of the onboard consumables management concept proposed for use on the Space Shuttle.

Quarkonium production in high energyproton-proton and proton-nucleus collisions

Energy Technology Data Exchange (ETDEWEB)

del Valle, Z C; Corcella, G; Fleuret, F; Ferreiro, E G; Kartvelishvili, V; Kopeliovich, B; Lansberg, J P; Lourenco, C; Martinez, G; Papadimitriou, V; Satz, H; Scomparin, E; Ullrich, T; Teryaev, O; Vogt, R; Wang, J X

2011-03-14

We present a brief overview of the most relevant current issues related to quarkonium production in high energy proton-proton and proton-nucleus collisions along with some perspectives. After reviewing recent experimental and theoretical results on quarkonium production in pp and pA collisions, we discuss the emerging field of polarization studies. Afterwards, we report on issues related to heavy-quark production, both in pp and pA collisions, complemented by AA collisions. To put the work in broader perpectives, we emphasize the need for new observables to investigate the quarkonium production mechanisms and reiterate the qualities that make quarkonia a unique tool for many investigations in particle and nuclear physics.

Protonation of pyridine. Vol. 2

Energy Technology Data Exchange (ETDEWEB)

Zahran, N F; Ghoniem, H; Helal, A I [Physics Dept., Nuclear Research Center, AEA., Cairo, (Egypt); Rasheed, N [Nuclear Material Authority, Cairo, (Egypt)

1996-03-01

Field ionization mass spectra of pyridine is measured using 10{mu}m activated wire. protonation of pyridine, is observed as an intense peak in the mass spectra. Charge distribution of pyridine molecule is calculated using the modified neglect of diatomic overlap (MNDO) technique, and consequently proton attachment is proposed to be on the nitrogen atom. Temperature dependence of (M+H){sup +} ion is investigated and discussed. MNDO calculations of the protonated species are done, and the proton affinity of pyridine molecule is estimated. Time dependence of the field ionization process of pyridine and protonated ions are observed and discussed. 5 figs.

Influence of substitution of the proton donor and proton acceptor abilities of molecules. 1. The development method of definition proton donor and proton acceptor abilities A-H containing molecules

International Nuclear Information System (INIS)

Nurulloev, M.; Narziev, B.N.; Islomov, Z.; Fayzieva, M.

2005-01-01

The influence of nature of the assistant is investigated in work, it is quantity and a site on proton donor and proton acceptor abilities. A-H containing organic connections and ways, of definition of these abilities are developed by the method, of IR spectroscopy. It is developed model and it offered a technique of definition of these abilities. It is shown that the proton donor and proton acceptor is abilities of molecules as constants, are one of individual physical and chemical characteristics A-H of containing organic connections. These sizes determine the abilities of molecules, to form the intermolecular hydrogen connections, disabilities of the H-complexes formed in condensed, environments concerning to the non replaced molecule

Expected proton signal sizes in the PRaVDA Range Telescope for proton Computed Tomography

International Nuclear Information System (INIS)

Price, T.; Parker, D.J.; Green, S.; Esposito, M.; Waltham, C.; Allinson, N.M.; Poludniowski, G.; Evans, P.; Taylor, J.; Manolopoulos, S.; Anaxagoras, T.; Nieto-Camero, J.

2015-01-01

Proton radiotherapy has demonstrated benefits in the treatment of certain cancers. Accurate measurements of the proton stopping powers in body tissues are required in order to fully optimise the delivery of such treaments. The PRaVDA Consortium is developing a novel, fully solid state device to measure these stopping powers. The PRaVDA Range Telescope (RT), uses a stack of 24 CMOS Active Pixel Sensors (APS) to measure the residual proton energy after the patient. We present here the ability of the CMOS sensors to detect changes in the signal sizes as the proton traverses the RT, compare the results with theory, and discuss the implications of these results on the reconstruction of proton tracks

A detection system for very low-energy protons from {beta}-delayed proton decay

Energy Technology Data Exchange (ETDEWEB)

Spiridon, A.; Pollacco, E.; Trache, L.; Simmons, E.; McCleskey, M.; Roeder, B. T.; Tribble, R. E.; Pascovici, G.; Riallot, M.; Mols, J. P.; Kebbiri, M. [Cyclotron Institute, Texas A and M University, College Station, TX 77843-3366 (United States); CEA/IRFU Saclay, Gif-sur-Yvette (France); Cyclotron Institute, Texas A and M University, College Station, TX 77843-3366 (United States); Institut fuer Kernphysik der Universitaet zu Koeln, D-50937 Koeln (Germany); CEA/IRFU Saclay, Gif-sur-Yvette (France)

2012-11-20

We have recently developed a gas based detection system called AstroBox, motivated by nuclear astrophysics studies. The goal was to detect very low-energy protons from {beta}-delayed p-decay with reduced beta background and improved energy resolution. The detector was tested using the {beta}-delayed proton-emitter 23Al previously studied with a set-up based on thin double-sided Si strip detectors. The proton spectrum obtained with AstroBox showed no beta background down to {approx}80 keV. The low energy (206 keV, 267 keV) proton peaks were positively identified, well separated, and the resolution was improved.

A detection system for very low-energy protons from β-delayed proton decay

International Nuclear Information System (INIS)

Spiridon, A.; Pollacco, E.; Trache, L.; Simmons, E.; McCleskey, M.; Roeder, B. T.; Tribble, R. E.; Pascovici, G.; Riallot, M.; Mols, J. P.; Kebbiri, M.

2012-01-01

We have recently developed a gas based detection system called AstroBox, motivated by nuclear astrophysics studies. The goal was to detect very low-energy protons from β-delayed p-decay with reduced beta background and improved energy resolution. The detector was tested using the β-delayed proton-emitter 23Al previously studied with a set-up based on thin double-sided Si strip detectors. The proton spectrum obtained with AstroBox showed no beta background down to ∼80 keV. The low energy (206 keV, 267 keV) proton peaks were positively identified, well separated, and the resolution was improved.

Modeling the Proton Radiation Belt With Van Allen Probes Relativistic Electron-Proton Telescope Data

Science.gov (United States)

Selesnick, R. S.; Baker, D. N.; Kanekal, S. G.; Hoxie, V. C.; Li, X.

2018-01-01

An empirical model of the proton radiation belt is constructed from data taken during 2013-2017 by the Relativistic Electron-Proton Telescopes on the Van Allen Probes satellites. The model intensity is a function of time, kinetic energy in the range 18-600 MeV, equatorial pitch angle, and L shell of proton guiding centers. Data are selected, on the basis of energy deposits in each of the nine silicon detectors, to reduce background caused by hard proton energy spectra at low L. Instrument response functions are computed by Monte Carlo integration, using simulated proton paths through a simplified structural model, to account for energy loss in shielding material for protons outside the nominal field of view. Overlap of energy channels, their wide angular response, and changing satellite orientation require the model dependencies on all three independent variables be determined simultaneously. This is done by least squares minimization with a customized steepest descent algorithm. Model uncertainty accounts for statistical data error and systematic error in the simulated instrument response. A proton energy spectrum is also computed from data taken during the 8 January 2014 solar event, to illustrate methods for the simpler case of an isotropic and homogeneous model distribution. Radiation belt and solar proton results are compared to intensities computed with a simplified, on-axis response that can provide a good approximation under limited circumstances.

A contribution towards establishing more comfortable space weather to cope with increased human space passengers for ISS shuttles

Science.gov (United States)

Kalu, A.

Space Weather is a specialized scienctific descipline in Meteorology which has recently emerged from man's continued research efforts to create a familiar spacecraft environment which is physiologically stable and life sustaining for astronauts and human passengers in distant space travels. As the population of human passengers in space shuttles rapidly increases, corresponding research on sustained micro-climate of spacecrafts is considered necessary and timely. This is because existing information is not meant for a large population in spacecrafts. The paper therefore discusses the role of meteorology (specifically micrometeorology) in relation to internal communication, spacecraft instrumentation and physiologic comfort of astronauts and space passengers (the later may not necessarily be trained astronauts, but merely business men or tourist space travellers for business transactions in the International Space Station (ISS)). It is recognized that me eorology which is a fundamental science amongt multidiscplinary sciences has been found to be vital in space travels and communication. Space weather therefore appears in slightly different format where temperature and humidity changes and variability within the spacecraft exert very significant influences on the efficiency of astronauts and the effectiveness of the various delicate instrument gadgets aimed at reducing the frequency of computer failures and malfunction of other instruments on which safety of the spacecraft depends. Apart from the engineering and technological problems which space scientists must have to overcome when human population in space shuttles increases as we now expect, based on evidence from successful missions to ISS, the maint enace of physiologic comfort state of astronauts, which, as far as scientifically possible, should be as near as possible to their Earth-Atmosphere condition. This is one of the most important and also most difficult conditions to attain. It demands a mor e

Proposal for construction of a proton--proton storage accelerator facility (Isabelle)

International Nuclear Information System (INIS)

1975-06-01

A proposal is made for the construction of proton storage rings at the Brookhaven Alternating Gradient Synchrotron (AGS) using superconducting magnets for which much of the technology has already been developed. This proton-proton colliding beam facility, ''ISABELLE,'' will provide large increases in both the center-of-mass energy and the luminosity, key machine parameters for high energy physics. The physics potential and the general description of the facility are discussed in detail, and the physical plant layout, a cost estimate and schedule, and future options are given.(U.S.)

A new impact picture for low and high energy proton-proton elastic scattering

International Nuclear Information System (INIS)

Bourrely, C.; Soffer, J.; Wu, Tai Tsun

1978-05-01

The impact picture that was used several years ago to predict the increase of total and integrated differential cross sections at high energies was improved significantly. The major improvements consist of the following: (1) the dependence of the Pomeron term on the momentum transfer is taken from a modified version of the relation between matter distribution and charge distribution; (2) Regge backgrounds are properly taken into account; and (3) a simple non-trivial form is used for the hadronic matter current in the proton. For proton-proton elastic scattering, the phenomenological differential cross section is in good agreement with the experimental data in the laboratory momentum range of 14 GeV/c to 2000 GeV/c, and is predicted for ISABELLE energy. Because of the third improvement, predictions are obtained for both polarization and R parameters for proton-proton elastic scattering

Space Shuttle main engine product improvement

Science.gov (United States)

Lucci, A. D.; Klatt, F. P.

1985-01-01

The current design of the Space Shuttle Main Engine has passed 11 certification cycles, amassed approximately a quarter million seconds of engine test time in 1200 tests and successfully launched the Space Shuttle 17 times of 51 engine launches through May 1985. Building on this extensive background, two development programs are underway at Rocketdyne to improve the flow of hot gas through the powerhead and evaluate the changes to increase the performance margins in the engine. These two programs, called Phase II+ and Technology Test Bed Precursor program are described. Phase II+ develops a two-tube hot-gas manifold that improves the component environment. The Precursor program will evaluate a larger throat main combustion chamber, conduct combustion stability testing of a baffleless main injector, fabricate an experimental weld-free heat exchanger tube, fabricate and test a high pressure oxidizer turbopump with an improved inlet, and develop and test methods for reducing temperature transients at start and shutdown.

Orbital Fitness: An Overview of Space Shuttle Cardiopulmonary Exercise Physiology Findings

Science.gov (United States)

Moore, Alan D.

2011-01-01

Limited observations regarding the cardiopulmonary responses to aerobic exercise had been conducted during short-duration spaceflight before the Space Shuttle program. This presentation focuses on the findings regarding changes observed in the cardiopulmonary exercise responses during and following Shuttle flights. During flight, maximum oxygen uptake (VO2max) remained unchanged as did the maximum work rate achievable during cycle exercise testing conducted during the last full flight day. Immediately following flight, the ubiquitous finding, confirmed by investigations conducted during the Spacelab Life Sciences missions 1 and 2 and by NASA Detailed Supplemental Objective studies, indicated that VO2max was reduced; however, the reduction in VO2max was transient and returned to preflight levels within 7 days following return. Studies regarding the influence of aerobic exercise countermeasures performed during flight on postflight performance were mostly limited to the examination of the heart rate (HR) response to submaximal exercise testing on landing day. These studies revealed that exercise HR was elevated in individuals who performed little to no exercise during their missions as compared to individuals who performed regular exercise. In addition, astronauts who performed little to no aerobic exercise during flight demonstrated an increased HR and lowered pulse pressure response to the standard stand test on landing day, indicating a decrease in orthostatic function in these individuals. With regard to exercise modality, four devices were examined during the Shuttle era: two treadmills, a cycle ergometer, and a rowing device. Although there were limited investigations regarding the use of these devices for exercise training aboard the Shuttle, there was no clear consensus reached regarding which proved to be a "superior" device. Each device had a unique operational or physiologic limitation associated with its use. In conclusion, exercise research conducted

Proton gradients and proton-dependent transport processes in the chloroplast

Directory of Open Access Journals (Sweden)

Ricarda eHöhner

2016-02-01

Full Text Available Proton gradients are fundamental to chloroplast function. Across thylakoid membranes, the light induced proton gradient is essential for ATP synthesis. As a result of proton pumping into the thylakoid lumen, an alkaline stromal pH develops, which is required for full activation of pH-dependent Calvin Benson cycle enzymes. This implies that a pH gradient between the cytosol (pH 7 and the stroma (pH 8 is established upon illumination. To maintain this pH gradient chloroplasts actively extrude protons. More than 30 years ago it was already established that these proton fluxes are electrically counterbalanced by Mg2+, K+ or Cl- fluxes, but only recently the first transport systems that regulate the pH gradient were identified. Notably several (Na+,K+/H+ antiporter systems where identified, that play a role in pH gradient regulation, ion homeostasis, osmoregulation, or coupling of secondary active transport. The established pH gradients are important to drive uptake of essential ions and solutes, but not many transporters involved have been identified to date. In this mini review we summarize the current status in the field and the open questions that need to be addressed in order to understand how pH gradients are maintained, how this is interconnected with other transport processes and what this means for chloroplast function.

Electron - proton colliders

International Nuclear Information System (INIS)

Wiik, B.H.

1985-01-01

Electron-proton storage rings allow us to study the interaction between the two basic constituents of matter, electrons and quarks at very short distances. Such machines were first discussed in connection with the ISR but the idea was abandoned because of the anticipated low counting rate. The interest in electron-proton storage rings was rekindeled by the discovery of large pointlike cross sections in lepton-hardon interactions and several/sup 2-15/ projects have been discussed during the past decade. However, despite a glorious past, which includes the discovery of quarks and neutral currents, and a multitude of proposals no electron-proton storage ring has ever been built. What we might learn by studying electron-proton collisions at high energies is discussed. After some brief comments on present proposals the proposed DESY ep project HERA is described as an example of how to realize such a machine

Shuttle requests

CERN Multimedia

2007-01-01

Please note that, to improve the service we provide, a new telephone number - 72500 - has been set up for all shuttle requests concerning: journeys within the CERN site, i.e. official visits or bidders' conferences; journeys to or from the airport or city centre; long-distance journeys. However, it will still be possible to submit requests in writing to Fm.Support@cern. The radio taxi can also still be reached on 76969. The TS/FM group would also like to inform you that details of all light logistics services (transport of persons, distribution and collection of parcels up to 1 tonne, distribution and collection of mail) can be found on the group's website: http://ts-dep.web.cern.ch/ts-dep/groups/fm/fm.htm TS/FM Group 160239

Probing the Spin Structure of the Proton Using Polarized Proton-Proton Collisions and the Production of W Bosons

Energy Technology Data Exchange (ETDEWEB)

Beaumier, Michael J. [Univ. of California, Riverside, CA (United States)

2016-08-01

This thesis discusses the process of extracting the longitudinal asymmetry, A$W±\\atop{L}$ describing W → μ production in forward kinematic regimes. This asymmetry is used to constrain our understanding of the polarized parton distribution functions characterizing $\\bar{u}$ and $\\bar{d}$ sea quarks in the proton. This asymmetry will be used to constrain the overall contribution of the sea-quarks to the total proton spin. The asymmetry is evaluated over the pseudorapidity range of the PHENIX Muon Arms, 2.1 < |η| 2.6, for longitudinally polarized proton-proton collisions at 510 GeV √s. In particular, I will discuss the statistical methods used to characterize real muonic W decays and the various background processes is presented, including a discussion of likelihood event selection and the Extended Unbinned Maximum Likelihood t. These statistical methods serve estimate the yields of W muonic decays, which are used to calculate the longitudinal asymmetry.

Journal of Proton Therapy

Directory of Open Access Journals (Sweden)

Editorial Office

2015-01-01

Full Text Available Journal of Proton Therapy (JPT is an international open access, peer-reviewed journal, which publishes original research, technical reports, reviews, case reports, editorials, and other materials on proton therapy with focus on radiation oncology, medical physics, medical dosimetry, and radiation therapy.No article processing/submission feeNo publication feePeer-review completion within 3-6 weeksImmediate publication after the completion of final author proofreadDOI assignment for each published articleFree access to published articles for all readers without any access barriers or subscriptionThe views and opinions expressed in articles are those of the author/s and do not necessarily reflect the policies of the Journal of Proton Therapy.Authors are encouraged to submit articles for publication in the inaugural issue of the Journal of Proton Therapy by online or email to editor@protonjournal.comOfficial Website of Journal of Proton Therapy: http://www.protonjournal.org/

Energizing porters by proton-motive force.

Science.gov (United States)

Nelson, N

1994-11-01

It is generally accepted that the chemistry of water was the most crucial determinant in shaping life on earth. Among the more important chemical features of water is its dissociation into protons and hydroxyl ions. The presence of relatively high proton concentrations in the ambient solution resulted in the evolution of proton pumps during the dawn of life on earth. These proton pumps maintained neutral pH inside the cells and generated electrochemical gradients of protons (proton-motive force) across their membranes. The existence of proton-motive force enabled the evolution of porters driven by it that are most probably among the more primitive porters in the world. The directionality of the substrate transport by the porters could be to both sides of the membranes because they can serve as proton symporters or antiporters. One of the most important subjects of this meeting is the mechanism by which proton-motive and other ion-motive forces drive the transport processes through porters. Is there a common mechanism of action for all proton-driven porters? Is there some common partial reaction by which we can identify the way that porters are energized by proton-motive force? Is there a common coupling between proton movement and uptake or secretion of certain molecules? Even a partial answer to one of these questions would advance our knowledge... or confusion. As my mentor Efraim Racker used to say: 'If you are not totally confused you do not understand the issue'.

Shuttle operations era planning for flight operations

Science.gov (United States)

Holt, J. D.; Beckman, D. A.

1984-01-01

The Space Transportation System (STS) provides routine access to space for a wide range of customers in which cargos vary from single payloads on dedicated flights to multiple payloads that share Shuttle resources. This paper describes the flight operations planning process from payload introduction through flight assignment to execution of the payload objectives and the changes that have been introduced to improve that process. Particular attention is given to the factors that influence the amount of preflight preparation necessary to satisfy customer requirements. The partnership between the STS operations team and the customer is described in terms of their functions and responsibilities in the development of a flight plan. A description of the Mission Control Center (MCC) and payload support capabilities completes the overview of Shuttle flight operations.

Shuttle Kit Freezer Refrigeration Unit Conceptual Design

Science.gov (United States)

Copeland, R. J.

1975-01-01

The refrigerated food/medical sample storage compartment as a kit to the space shuttle orbiter is examined. To maintain the -10 F in the freezer kit, an active refrigeration unit is required, and an air cooled Stirling Cycle refrigerator was selected. The freezer kit contains two subsystems, the refrigeration unit, and the storage volume. The freezer must provide two basic capabilities in one unit. One requirement is to store 215 lbs of food which is consumed in a 30-day period by 7 people. The other requirement is to store 128.3 lbs of medical samples consisting of both urine and feces. The unit can be mounted on the lower deck of the shuttle cabin, and will occupy four standard payload module compartments on the forward bulkhead. The freezer contains four storage compartments.

Image Analysis Based on Soft Computing and Applied on Space Shuttle During the Liftoff Process

Science.gov (United States)

Dominquez, Jesus A.; Klinko, Steve J.

2007-01-01

Imaging techniques based on Soft Computing (SC) and developed at Kennedy Space Center (KSC) have been implemented on a variety of prototype applications related to the safety operation of the Space Shuttle during the liftoff process. These SC-based prototype applications include detection and tracking of moving Foreign Objects Debris (FOD) during the Space Shuttle liftoff, visual anomaly detection on slidewires used in the emergency egress system for the Space Shuttle at the laJlIlch pad, and visual detection of distant birds approaching the Space Shuttle launch pad. This SC-based image analysis capability developed at KSC was also used to analyze images acquired during the accident of the Space Shuttle Columbia and estimate the trajectory and velocity of the foam that caused the accident.

Rapid urbanization and the need for sustainable transportation policies in Jakarta

Science.gov (United States)

Rukmana, D.

2018-03-01

Not only is Jakarta the largest metropolitan area in Southeast Asia, it is the also one of the most dynamic, though beset with most of the urban problems experienced in twenty-first century Southeast Asia. Batavia, colonial capital of the Netherland Indies in the first half of the 20th century was a small urban area of approximately 150,000 residents. In the second half, Batavia became Jakarta, the 28 million megacity capital of independent Indonesia. Among many urban problems, one major problem plagued Jakarta in the last two decades is traffic congestions. This paper discusses the extent to which rapid urbanization in Jakarta has contributed to the need for sustainable transportation policies in Jakarta. The development of MRT could be viable solutions to alleviate the acute traffic jams in Jakarta. Jakarta will need to implement other innovative sustainable transportation policies including promoting active live through more walking and bicycling, carpool matching services, shuttle services, telecommuting and downzoning in downtown areas.

Study of proton and 2 protons emission from light neutron deficient nuclei around A=20

International Nuclear Information System (INIS)

Zerguerras, T.

2001-09-01

Proton and two proton emission from light neutron deficient nuclei around A=20 have been studied. A radioactive beam of 18 Ne, 17 F and 20 Mg, produced at the Grand Accelerateur National d'Ions Lourds by fragmentation of a 24 Mg primary beam at 95 MeV/A, bombarded a 9 Be target to form unbound states. Proton(s) and nuclei from the decay were detected respectively in the MUST array and the SPEG spectrometer. From energy and angle measurements, the invariant mass of the decaying nucleus could be reconstructed. Double coincidence events between a proton and 17 F, 16 O, 15 O, 14 O and 18 Ne were registered to obtain excitation energy spectra of 18 Ne, 17 F, 16 F, 15 F et 19 Na. Generally, the masses measures are in agreement with previous experiments. In the case of 18 Ne, excitation energy and angular distributions agree well with the predictions of a break up model calculation. From 17 Ne proton coincidences, a first experimental measurement of the ground state mass excess of 18 Na has been obtained and yields 24,19(0,15)MeV. Two proton emission from 17 Ne and 18 Ne excited states and the 19 Mg ground state was studied through triple coincidences between two proton and 15 O, 16 O and 17 Ne respectively. In the first case, the proton-proton relative angle distribution in the center of mass has been compared with model calculation. Sequential emission from excited states of 17 Ne, above the proton emission threshold, through 16 F is dominant but a 2 He decay channel could not be excluded. No 2 He emission from the 1.288 MeV 17 Ne state, or from the 6.15 MeV 18 Ne state has been observed. Only one coincidence event between 17 Ne and two proton was registered, the value of the one neutron stripping reaction cross section of 20 Mg being much lower than predicted. (author)

Beam-Beam Effects in the SPS Proton-Anti Proton Collider

CERN Document Server

Cornelis, K.

2014-01-01

During the proton-anti proton collider run several experiments were carried out in order to understand the effect of the beam-beam interaction on backgrounds and lifetimes. In this talk a selection of these experiments will be presented. From these experiments, the importance of relative beam sizes and tune ripple could be demonstrated.

Research study on antiskid braking systems for the space shuttle

Science.gov (United States)

Auselmi, J. A.; Weinberg, L. W.; Yurczyk, R. F.; Nelson, W. G.

1973-01-01

A research project to investigate antiskid braking systems for the space shuttle vehicle was conducted. System from the Concorde, Boeing 747, Boeing 737, and Lockheed L-1011 were investigated. The characteristics of the Boeing 737 system which caused it to be selected are described. Other subjects which were investigated are: (1) trade studies of brake control concepts, (2) redundancy requirements trade study, (3) laboratory evaluation of antiskid systems, and (4) space shuttle hardware criteria.

Restrained Proton Indicator in Combined Quantum-Mechanics/Molecular-Mechanics Dynamics Simulations of Proton Transfer through a Carbon Nanotube.

Science.gov (United States)

Duster, Adam W; Lin, Hai

2017-09-14

Recently, a collective variable "proton indicator" was purposed for tracking an excess proton solvated in bulk water in molecular dynamics simulations. In this work, we demonstrate the feasibility of utilizing the position of this proton indicator as a reaction coordinate to model an excess proton migrating through a hydrophobic carbon nanotube in combined quantum-mechanics/molecular-mechanics simulations. Our results indicate that applying a harmonic restraint to the proton indicator in the bulk solvent near the nanotube pore entrance leads to the recruitment of water molecules into the pore. This is consistent with an earlier study that employed a multistate empirical valence bond potential and a different representation (center of excess charge) of the proton. We attribute this water recruitment to the delocalized nature of the solvated proton, which prefers to be in high-dielectric bulk solvent. While water recruitment into the pore is considered an artifact in the present simulations (because of the artificially imposed restraint on the proton), if the proton were naturally restrained, it could assist in building water wires prior to proton transfer through the pore. The potential of mean force for a proton translocation through the water-filled pore was computed by umbrella sampling, where the bias potentials were applied to the proton indicator. The free energy curve and barrier heights agree reasonably with those in the literature. The results suggest that the proton indicator can be used as a reaction coordinate in simulations of proton transport in confined environments.

Proton therapy

International Nuclear Information System (INIS)

Jongen, Y.

1995-01-01

Ideal radiotherapy deposits a large amount of energy in the tumour volume, and none in the surrounding healthy tissues. Proton therapy comes closer to this goal because of a greater concentration of dose, well defined proton ranges and points of energy release which are precisely known - the Bragg peak1. In the past, the development of clinical proton therapy has been hampered by complexity, size, and cost. To be clinically effective, energies of several hundred MeV are required; these were previously unavailable for hospital installations, and pioneering institutions had to work with complex, inadequate equipment originally intended for nuclear physics research. Recently a number of specialist organizations and commercial companies have been working on dedicated systems for proton therapy. One, IBA of Belgium, has equipment for inhouse hospital operation which encompasses a complete therapy centre, delivered as a turnkey package and incorporating a compact, automated, higher energy cyclotron with isocentric gantries. Their system will be installed at Massachusetts General Hospital, Boston. The proton therapy system comprises: - a 235 MeV isochronous cyclotron to deliver beams of up to 1.5 microamps, but with a hardware limitation to restrict the maximum possible dose; - variable energy beam (235 to 70 MeV ) with energy spread and emittance verification; - a beam transport and switching system to connect the exit of the energy selection system to the entrances of a number of gantries and fixed beamlines. Along the beam transport system, the beam characteristics are monitored with non-interceptive multiwire ionization chambers for automatic tuning; - gantries fitted with nozzles and beamline elements for beam control; both beam scattering and beam wobbling techniques are available for shaping the beam;

Fractional Consumption of Liquid Hydrogen and Liquid Oxygen During the Space Shuttle Program

Science.gov (United States)

Partridge, Jonathan K.

2011-01-01

The Space Shuttle uses the propellants, liquid hydrogen and liquid oxygen, to meet part of the propulsion requirements from ground to orbit. The Kennedy Space Center procured over 25 million kilograms of liquid hydrogen and over 250 million kilograms of liquid oxygen during the 3D-year Space Shuttle Program. Because of the cryogenic nature of the propellants, approximately 55% of the total purchased liquid hydrogen and 30% of the total purchased liquid oxygen were used in the Space Shuttle Main Engines. The balance of the propellants were vaporized during operations for various purposes. This paper dissects the total consumption of liqUid hydrogen and liqUid oxygen and determines the fraction attributable to each of the various processing and launch operations that occurred during the entire Space Shuttle Program at the Kennedy Space Center.

Sustained delivery of plasmid DNA from polymeric scaffolds for tissue engineering.

Science.gov (United States)

Storrie, Hannah; Mooney, David J

2006-07-07

The encapsulation of DNA into polymeric depot systems can be used to spatially and temporally control DNA release, leading to a sustained, local delivery of therapeutic factors for tissue regeneration. Prior to encapsulation, DNA may be condensed with cationic polymers to decrease particle size, protect DNA from degradation, promote interaction with cell membranes, and facilitate endosomal release via the proton sponge effect. DNA has been encapsulated with either natural or synthetic polymers to form micro- and nanospheres, porous scaffolds and hydrogels for sustained DNA release and the polymer physical and chemical properties have been shown to influence transfection efficiency. Polymeric depot systems have been applied for bone, skin, and nerve regeneration as well as therapeutic angiogenesis, indicating the broad applicability of these systems for tissue engineering.

Correlations between high momentum particles in proton-proton collisions at high energies

International Nuclear Information System (INIS)

Bobbink, G.J.

1981-01-01

This thesis describes an experiment performed at the CERN Intersecting Storage Rings. The experiment studies the reaction p+p→h 1 +h 2 +X at two centre-of-mass energies, √s=44.7 GeV and √s=62.3 GeV. Two of the outgoing particles (h 1 and h 2 ) are detected in opposite c.m.s. hemispheres at small polar angles with respect to the direction of two incident protons. The remaining particles produced (X) are not detected. The hadrons hsub(i) are identified mesons (π + , π - , K + , K - ) or baryons (p, Λ) with relatively large longitudinal psub(L) and small transverse momentum psub(T). The aim of the experiment is twofold. The first aim is to study whether the momentum distributions of the fast particles hsub(i) are correlated and thereby to constrain the possible interaction mechanisms responsible for the production of high psub(L), low psub(T) particles. The second aim is to establish to what extent the production of pions and kaons in inclusive proton-proton collisions (e.g. p+p→π+X, X=all other particles) resembles the production of pions and kaons in diffractive proton-proton collisions (e.g. p+p→p+π+X, in which the final-state proton has a momentum close to its maximum possible value). (Auth.)

Medical Proton Accelerator Project

International Nuclear Information System (INIS)

Comsan, M.N.H.

2008-01-01

A project for a medical proton accelerator for cancer treatment is outlined. The project is motivated by the need for a precise modality for cancer curing especially in children. Proton therapy is known by its superior radiation and biological effectiveness as compared to photon or electron therapy. With 26 proton and 3 heavy-ion therapy complexes operating worldwide only one (p) exists in South Africa, and none in south Asia and the Middle East. The accelerator of choice should provide protons with energy 75 MeV for eye treatment and 250 MeV for body treatment. Four treatment rooms are suggested: two with isocentric gantries, one with fixed beams and one for development. Passive scanning is recommended. The project can serve Middle East and North Africa with ∼ 400 million populations. The annual capacity of the project is estimated as 1,100 to be compared with expected radiation cases eligible for proton cancer treatment of not less than 200,000

Impact parameter analysis of proton-proton elastic and inelastic interactions at 360 GeV/c

International Nuclear Information System (INIS)

Banerjee, S.; Ragavan, R.; Bailly, J

1987-01-01

Data obtained with the European Hybrid Spectrometer on the proton-proton elastic scattering at 360 GeV/c are presented. The differential cross sections of elastic and inelastic pp-interactions are studied as a function of the impact parameter. The results are compared to those obtained at other energies. They are interpreted in the framework of a simple geometrical Monte-Carlo model of inelastic collisions considering protons as composite particles having a definite effective radius with valence quarks inside. The shape of the inelastic overlap function is well reproduced for both pp- and π + p-interactions. The effective radii of the proton and pion as well as of the valence quarks are estimated for inelastic interactions. The model calculations indicate an increase of the effective radii both of protons and valence quarks and an increase of the proton opacity with increasing energy

Feasibility analysis of cislunar flight using the Shuttle Orbiter

Science.gov (United States)

Haynes, Davy A.

1991-01-01

A first order orbital mechanics analysis was conducted to examine the possibility of utilizing the Space Shuttle Orbiter to perform payload delivery missions to lunar orbit. In the analysis, the earth orbit of departure was constrained to be that of Space Station Freedom. Furthermore, no enhancements of the Orbiter's thermal protection system were assumed. Therefore, earth orbit insertion maneuvers were constrained to be all propulsive. Only minimal constraints were placed on the lunar orbits and no consideration was given to possible landing sites for lunar surface payloads. The various phases and maneuvers of the mission are discussed for both a conventional (Apollo type) and an unconventional mission profile. The velocity impulses needed, and the propellant masses required are presented for all of the mission maneuvers. Maximum payload capabilities were determined for both of the mission profiles examined. In addition, other issues relating to the feasibility of such lunar shuttle missions are discussed. The results of the analysis indicate that the Shuttle Orbiter would be a poor vehicle for payload delivery missions to lunar orbit.

Violent collisions of spinning protons

Energy Technology Data Exchange (ETDEWEB)

Krisch, A.D. [Michigan Univ., Spin Physics Center, Ann Arbor, MI (United States)

2005-07-01

The author draws the history of polarized proton beams that has relied on experiments that took place in different accelerators like ZGS (zero gradient synchrotron, Argonne), AGS (Brookhaven) and Fermilab from 1973 till today. The first studies of the behavior and spin-manipulation of polarized protons helped in developing polarized beams around the world: Brookhaven now has 200 GeV polarized protons in the RHIC collider, perhaps someday the 7 TeV LHC at CERN might have polarized protons.

Proton-counting radiography for proton therapy: a proof of principle using CMOS APS technology

International Nuclear Information System (INIS)

Poludniowski, G; Esposito, M; Evans, P M; Allinson, N M; Anaxagoras, T; Green, S; Parker, D J; Price, T; Manolopoulos, S; Nieto-Camero, J

2014-01-01

Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography applications such as computed tomography (CT), the water-equivalent-path-length that each proton has travelled through an imaged object must be inferred. Typically, scintillator-based technology has been used in various energy/range telescope designs. Here we propose a very different alternative of using radiation-hard CMOS active pixel sensor technology. The ability of such a sensor to resolve the passage of individual protons in a therapy beam has not been previously shown. Here, such capability is demonstrated using a 36 MeV cyclotron beam (University of Birmingham Cyclotron, Birmingham, UK) and a 200 MeV clinical radiotherapy beam (iThemba LABS, Cape Town, SA). The feasibility of tracking individual protons through multiple CMOS layers is also demonstrated using a two-layer stack of sensors. The chief advantages of this solution are the spatial discrimination of events intrinsic to pixelated sensors, combined with the potential provision of information on both the range and residual energy of a proton. The challenges in developing a practical system are discussed. (paper)

Proton-counting radiography for proton therapy: a proof of principle using CMOS APS technology.

Science.gov (United States)

Poludniowski, G; Allinson, N M; Anaxagoras, T; Esposito, M; Green, S; Manolopoulos, S; Nieto-Camero, J; Parker, D J; Price, T; Evans, P M

2014-06-07

Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography applications such as computed tomography (CT), the water-equivalent-path-length that each proton has travelled through an imaged object must be inferred. Typically, scintillator-based technology has been used in various energy/range telescope designs. Here we propose a very different alternative of using radiation-hard CMOS active pixel sensor technology. The ability of such a sensor to resolve the passage of individual protons in a therapy beam has not been previously shown. Here, such capability is demonstrated using a 36 MeV cyclotron beam (University of Birmingham Cyclotron, Birmingham, UK) and a 200 MeV clinical radiotherapy beam (iThemba LABS, Cape Town, SA). The feasibility of tracking individual protons through multiple CMOS layers is also demonstrated using a two-layer stack of sensors. The chief advantages of this solution are the spatial discrimination of events intrinsic to pixelated sensors, combined with the potential provision of information on both the range and residual energy of a proton. The challenges in developing a practical system are discussed.

Concept for a Future Super Proton-Proton Collider

Energy Technology Data Exchange (ETDEWEB)

Tang, Jingyu; et al.

2015-07-12

Following the discovery of the Higgs boson at LHC, new large colliders are being studied by the international high-energy community to explore Higgs physics in detail and new physics beyond the Standard Model. In China, a two-stage circular collider project CEPC-SPPC is proposed, with the first stage CEPC (Circular Electron Positron Collier, a so-called Higgs factory) focused on Higgs physics, and the second stage SPPC (Super Proton-Proton Collider) focused on new physics beyond the Standard Model. This paper discusses this second stage.

Concept for a Future Super Proton-Proton Collider

CERN Document Server

Tang, Jingyu; Chai, Weiping; Chen, Fusan; Chen, Nian; Chou, Weiren; Dong, Haiyi; Gao, Jie; Han, Tao; Leng, Yongbin; Li, Guangrui; Gupta, Ramesh; Li, Peng; Li, Zhihui; Liu, Baiqi; Liu, Yudong; Lou, Xinchou; Luo, Qing; Malamud, Ernie; Mao, Lijun; Palmer, Robert B.; Peng, Quanling; Peng, Yuemei; Ruan, Manqi; Sabbi, GianLuca; Su, Feng; Su, Shufang; Stratakis, Diktys; Sun, Baogeng; Wang, Meifen; Wang, Jie; Wang, Liantao; Wang, Xiangqi; Wang, Yifang; Wang, Yong; Xiao, Ming; Xing, Qingzhi; Xu, Qingjin; Xu, Hongliang; Xu, Wei; Witte, Holger; Yan, Yingbing; Yang, Yongliang; Yang, Jiancheng; Yuan, Youjin; Zhang, Bo; Zhang, Yuhong; Zheng, Shuxin; Zhu, Kun; Zhu, Zian; Zou, Ye

2015-01-01

Following the discovery of the Higgs boson at LHC, new large colliders are being studied by the international high-energy community to explore Higgs physics in detail and new physics beyond the Standard Model. In China, a two-stage circular collider project CEPC-SPPC is proposed, with the first stage CEPC (Circular Electron Positron Collier, a so-called Higgs factory) focused on Higgs physics, and the second stage SPPC (Super Proton-Proton Collider) focused on new physics beyond the Standard Model. This paper discusses this second stage.

Parity Non-Conservation in Proton-Proton Elastic Scattering

International Nuclear Information System (INIS)

Brown, V.R.; B.F. Gibson; J.A. Carlson; R. Schiavilla

2002-01-01

The parity non-conserving longitudinal asymmetry in proton-proton (pp) elastic scattering is calculated in the lab-energy range 0-350 MeV using contemporary, realistic strong-interaction potentials combined with a weak-interaction potential comprised of rho- and omega-meson exchanges as exemplified by the DDH model. Values for the rho- and omega-meson coupling constants, h rho rho rho and h rho rho omega , are determined from comparison with the measured asymmetries at 13.6 MeV, 45 MeV, and 221 MeV

Microdosimetry measurements with the RME-III on the space shuttle

International Nuclear Information System (INIS)

Hardy, K.; Golightly, M.J.; Atwell, W.; Quam, W.

1994-01-01

Since December 1988 (STS-27) the USAF Armstrong Laboratory, in conjunction with the NASA Space Radiation Analysis Group, has been conducting microdosimetry measurements on selected high-altitude, high-inclination Space Shuttle mission with the RME-III. The RME-III is a portable, self-contained, active dosimeter system featuring a three-channel tissue equivalent proportional counter (TEPC) which measures particle fluence and computes dose and dose equivalent at operator selected time intervals. The total accumulated absorbed dose and dose equivalent are displayed real time, while the data and the time of the interval dose readings are stored in memory modules for later analysis. Analysis of the time-resolved data permits correlation of the radiation exposure with geographic position, altitude, and spacecraft shielding and orientation. The RME-III has flown on 15 Shuttle missions to date and measurements are in good agreement with other dosimetry measurements made on the Shuttle

Protonic decay of oriented nuclei

International Nuclear Information System (INIS)

Kadmensky, S.G.

2002-01-01

On the basis of the multiparticle theory of protonic decay, the angular distributions of protons emitted by oriented spherical and deformed nuclei in the laboratory frame and in the internal coordinate frame of deformed parent nuclei are constructed with allowance for symmetry with respect to time inversion. It is shown that, because of the deep-subbarrier character of protonic decay, the adiabatic approximation is not applicable to describing the angular distributions of protons emitted by oriented deformed nuclei and that the angular distribution of protons in the laboratory frame does not coincide with that in the internal coordinate frame. It is demonstrated that these angular distributions coincide only if the adiabatic and the semiclassical approximation are simultaneously valid

Ultrafast laser driven micro-lens to focus and energy select MeV protons

International Nuclear Information System (INIS)

Toncian, Toma

2008-05-01

A technique for simultaneous focusing and energy selection of high-current, MeV proton beams using radial, transient electric fields (10 7 -10 10 V/m) triggered on the inner wall of a hollow micro-cylinder by an intense, sub-picosecond laser-pulse is presented. Due to the transient nature of the radial focusing field, the proposed method allows selection of a desired range out of the spectrum of the poly-energetic proton beam. This technique addresses current drawbacks of laser-accelerated proton beams, i.e. their broad spectrum and divergence at the source. This thesis presents both experimental and computational studies that led to the understanding of the physical processes driving the micro-lens. After an one side irradiation of a hollow metallic cylinder a radial electric field develops inside the cylinder. Hot electrons generated by the interaction between laser pulse and cylinder wall spread inside the cylinder generating a plasma at the wall. This plasma expands into vacuum and sustains an electric field that acts as a collecting lens on a proton beam propagating axially through the cylinder. Both focusing and the reduction of the intrinsic beam divergence from 20 deg to.3 deg for a narrow spectral range was demonstrated. By sub-aperturing the beam a narrow spectral range (δε/ε < 3%) was selected from the poly-energetic beam. The micro-lens properties are tunable allowing for optimization towards applications. Optical probing techniques and proton imaging were employed to study the spacial and temporal evolution of the field and revealed a complex physical scenario of the rise and decay of the radial electric field. Each aspect studied experimentally is interpreted using 2D PIC and ray tracing simulations. A very good agreement between the experimental and computational data is found. The PIC simulations are used to upscale the demonstrated micro-lens capabilities to the focusing of a 270 MeV proton beam, an energy relevant for medical applications such

Ultrafast laser driven micro-lens to focus and energy select MeV protons

Energy Technology Data Exchange (ETDEWEB)

Toncian, Toma

2008-05-15

A technique for simultaneous focusing and energy selection of high-current, MeV proton beams using radial, transient electric fields (10{sup 7}-10{sup 10} V/m) triggered on the inner wall of a hollow micro-cylinder by an intense, sub-picosecond laser-pulse is presented. Due to the transient nature of the radial focusing field, the proposed method allows selection of a desired range out of the spectrum of the poly-energetic proton beam. This technique addresses current drawbacks of laser-accelerated proton beams, i.e. their broad spectrum and divergence at the source. This thesis presents both experimental and computational studies that led to the understanding of the physical processes driving the micro-lens. After an one side irradiation of a hollow metallic cylinder a radial electric field develops inside the cylinder. Hot electrons generated by the interaction between laser pulse and cylinder wall spread inside the cylinder generating a plasma at the wall. This plasma expands into vacuum and sustains an electric field that acts as a collecting lens on a proton beam propagating axially through the cylinder. Both focusing and the reduction of the intrinsic beam divergence from 20 deg to.3 deg for a narrow spectral range was demonstrated. By sub-aperturing the beam a narrow spectral range ({delta}{epsilon}/{epsilon} < 3%) was selected from the poly-energetic beam. The micro-lens properties are tunable allowing for optimization towards applications. Optical probing techniques and proton imaging were employed to study the spacial and temporal evolution of the field and revealed a complex physical scenario of the rise and decay of the radial electric field. Each aspect studied experimentally is interpreted using 2D PIC and ray tracing simulations. A very good agreement between the experimental and computational data is found. The PIC simulations are used to upscale the demonstrated micro-lens capabilities to the focusing of a 270 MeV proton beam, an energy relevant

Proton transfer events in GFP

NARCIS (Netherlands)

Di Donato, M.; van Wilderen, L.J.G.W.; van Stokkum, I.H.M.; Cohen Stuart, T.A.; Kennis, J.T.M.; Hellingwerf, K.J.; van Grondelle, R.; Groot, M.L.

2011-01-01

Proton transfer is one of the most important elementary processes in biology. Green fluorescent protein (GFP) serves as an important model system to elucidate the mechanistic details of this reaction, because in GFP proton transfer can be induced by light absorption. Illumination initiates proton

Pauli principle in the soft-photon approach to proton-proton bremsstrahlung

NARCIS (Netherlands)

Liou, MK; Timmermans, R; Gibson, BF

1996-01-01

A relativistic and manifestly gauge-invariant soft-photon amplitude, which is consistent with the soft-photon theorem and satisfies the Pauli principle, is derived for the proton-proton bremsstrahlung process. This soft-photon amplitude is the first two-u-two-t special amplitude to satisfy all

Measurements of low energy observables in proton-proton collisions with the ATLAS Detector.

CERN Document Server

Myska, Miroslav; The ATLAS collaboration

2017-01-01

Low energy phenomena have been studied in detail at the LHC, providing important input for improving models of non-perturbative QCD effects. The ATLAS collaboration has performed several new measurements in this sector: We present charged-particle distributions sensitive to the underlying event, measured by the ATLAS detector in proton--proton collisions at a centre-of-mass energy of 13 TeV. The results are corrected for detector effects and compared to predictions from various Monte Carlo generators. ATLAS has also studied the correlated hadron production. In particular, an analysis of the momentum difference between charged hadrons in high–energy proton–proton collisions is performed and the results are compared to the predictions of a helical QCD string fragmentation model. New results in forward physics are expected to be available soon. We close this presentation with the measurement of the exclusive "\\gamma\\gamma \\rightarrow \\mu^{+}\\mu^{-}" production in proton-proton collisions at a center-of-mass ...

Proton Conductive Channel Optimization in Methanol Resistive Hybrid Hyperbranched Polyamide Proton Exchange Membrane

Directory of Open Access Journals (Sweden)

Liying Ma

2017-12-01

Full Text Available Based on a previously developed polyamide proton conductive macromolecule, the nano-scale structure of the self-assembled proton conductive channels (PCCs is adjusted via enlarging the nano-scale pore size within the macromolecules. Hyperbranched polyamide macromolecules with different size are synthesized from different monomers to tune the nano-scale pore size within the macromolecules, and a series of hybrid membranes are prepared from these two micromoles to optimize the PCC structure in the proton exchange membrane. The optimized membrane exhibits methanol permeability low to 2.2 × 10−7 cm2/s, while the proton conductivity of the hybrid membrane can reach 0.25 S/cm at 80 °C, which was much higher than the value of the Nafion 117 membrane (0.192 S/cm. By considering the mechanical, dimensional, and the thermal properties, the hybrid hyperbranched polyamide proton exchange membrane (PEM exhibits promising application potential in direct methanol fuel cells (DMFC.

Exceptional power density and stability at intermediate temperatures in protonic ceramic fuel cells

Science.gov (United States)

Choi, Sihyuk; Kucharczyk, Chris J.; Liang, Yangang; Zhang, Xiaohang; Takeuchi, Ichiro; Ji, Ho-Il; Haile, Sossina M.

2018-03-01

Over the past several years, important strides have been made in demonstrating protonic ceramic fuel cells (PCFCs). Such fuel cells offer the potential of environmentally sustainable and cost-effective electric power generation. However, their power outputs have lagged behind predictions based on their high electrolyte conductivities. Here we overcome PCFC performance and stability challenges by employing a high-activity cathode, PrBa0.5Sr0.5Co1.5Fe0.5O5+δ (PBSCF), in combination with a chemically stable electrolyte, BaZr0.4Ce0.4Y0.1Yb0.1O3 (BZCYYb4411). We deposit a thin dense interlayer film of the cathode material onto the electrolyte surface to mitigate contact resistance, an approach which is made possible by the proton permeability of PBSCF. The peak power densities of the resulting fuel cells exceed 500 mW cm-2 at 500 °C, while also offering exceptional, long-term stability under CO2.

Space shuttle booster multi-engine base flow analysis

Science.gov (United States)

Tang, H. H.; Gardiner, C. R.; Anderson, W. A.; Navickas, J.

1972-01-01

A comprehensive review of currently available techniques pertinent to several prominent aspects of the base thermal problem of the space shuttle booster is given along with a brief review of experimental results. A tractable engineering analysis, capable of predicting the power-on base pressure, base heating, and other base thermal environmental conditions, such as base gas temperature, is presented and used for an analysis of various space shuttle booster configurations. The analysis consists of a rational combination of theoretical treatments of the prominent flow interaction phenomena in the base region. These theories consider jet mixing, plume flow, axisymmetric flow effects, base injection, recirculating flow dynamics, and various modes of heat transfer. Such effects as initial boundary layer expansion at the nozzle lip, reattachment, recompression, choked vent flow, and nonisoenergetic mixing processes are included in the analysis. A unified method was developed and programmed to numerically obtain compatible solutions for the various flow field components in both flight and ground test conditions. Preliminary prediction for a 12-engine space shuttle booster base thermal environment was obtained for a typical trajectory history. Theoretical predictions were also obtained for some clustered-engine experimental conditions. Results indicate good agreement between the data and theoretical predicitons.

Proton Beam Writing

International Nuclear Information System (INIS)

Rajta, I.; Szilasi, S.Z.; Csige, I.; Baradacs, E.

2005-01-01

Complete text of publication follows. Refractive index depth profile in PMMA due to proton irradiation Proton Beam Writing has been successfully used to create buried channel waveguides in PMMA, which suggested that proton irradiation increases the refractive index. To investigate this effect, PMMA samples were irradiated by 1.7-2.1 MeV proton beam. Spectroscopic Ellipsometry has been used to investigate the depth profile of the refractive index. An increase of the refractive index was observed in the order of 0.01, which is approximately one order of magnitude higher than the detection limit. The highest increase of the refractive index occurs at the end of range, i.e. we found a good correlation with the Bragg curve of the energy loss. Hardness changes in PMMA due to proton beam micromachining As protons penetrate a target material and lose their energy according to the Bragg curve, the energy loss is different at different depths. This causes depth-dependent changes of some physical properties in the target material (e.g. refractive index, hardness). In order to characterize the changes of hardness and other mechanical properties as a function of beam penetration depth, systematic investigations have been performed on PMMA, the most common resist material used in proton beam micromachining. Silicon check valve made by proton beam micromachining The possible application of Proton Beam Micromachining (PBM) has been demonstrated by a few authors for creating 3D Si microstructures. In this work we present alternative methods for the formation of a simple a non-return valve for microfluidic applications. Two different approaches have been applied, in both cases we exploited characteristic features of the PBM technique and the selective formation and dissolution of porous Si over the implantation damaged areas. In the first case we implanted 10 μm thick cantilever-type membrane of the valve normally to the crystal surface and at 30-60 degrees to the sidewalls of the

Aspects of the fundamental theory of proton-proton scattering

CERN Document Server

Martin, A

1973-01-01

After recalling the existence of a high energy bound on proton-proton total cross-sections, the author discusses the various phenomena which occur when these cross-sections rise and especially when they have the qualitative behaviour of the bound: rising elastic cross- sections, shrinking diffraction peak, validity of the Pomeranchuk theorem for total and elastic cross-sections, existence of a positive real part of the forward amplitude at high energies. (16 refs).

Selection of jets produced in 13TeV proton-proton collisions with the ATLAS detector

CERN Document Server

The ATLAS collaboration

2015-01-01

Quality criteria for the selection of reconstructed anti-$k_t$ jets with $R = 0.4$ in the ATLAS detector are described. The study is based on data recorded in June 2015 by the ATLAS experiment in $\\sqrt{s}$ = 13 TeV protonâproton collisions at the Large Hadron Collider, with a total integrated luminosity of 6.4 pb$^{−1}$. Two selection criteria are introduced. The Loose selection is designed to provide an efficiency of selecting jets from proton-proton collisions above 99.5% (99.9%) for $p_T>$ 20 (100) GeV to be used in most ATLAS physics analyses. A tighter set of selection cuts, called Tight, is designed to further reject background jets for analyses sensitive to non-collision backgrounds with an efficiency of selecting jets from proton-proton collisions above 95% (99.5%) for $p_T>$ 20 (100) GeV.

Conceptual design of proton beam window

International Nuclear Information System (INIS)

Teraoku, Takuji; Kaminaga, Masanori; Terada, Atsuhiko; Ishikura, Syuichi; Kinoshita, Hidetaka; Hino, Ryutaro

2001-01-01

In a MW-scale neutron scattering facility coupled with a high-intensity proton accelerator, a proton beam window is installed as the boundary between a high vacuum region of the proton beam transport line and a helium environment around the target assembly working as a neutron source. The window is cooled by water so as to remove high volumetric heat generated by the proton beam. A concept of the flat-type proton beam window consisting of two plates of 3 mm thick was proposed, which was found to be feasible under the proton beam power of 5 MW through thermal-hydraulic and structural strength analyses. (authors)

Large-sub(pT) production of single and double photons in proton-proton and pion-proton collisions

International Nuclear Information System (INIS)

Berger, E.L.; Argonne National Lab., IL; Braaten, E.; Field, R.D.

1984-01-01

Quantum chromodynamic (QCD) predictions are made for the large transverse momentum production of single and double photons in proton-proton, proton-antiproton, and pion-proton collisions. In π - p collisions at center-of-mass energy W=27.4 GeV and psub(T)=4.0 GeV, it is estimated that about 0.3% of the 90 0 single photon triggers will be balanced on the 'away-side' by a single photon with roughly the same transverse momentum. In π + p collisions this fraction drops to about 0.09%. These fractions increase with psub(T). In addition to the pure QED annihilation term qanti q -> γγ, it is found that the QCD-induced subprocess gg -> γγ provides an important source of double photons. Photon bremsstrahlung contributions are also examined. Experimental study of the systematics of single and double photon production in hadron-hadron collisions will provide information on the size of the strong interaction coupling constant, αsub(s)(Q), and on the charges of the quarks. Knowledge of the gluon distributions within hadrons and of the effective transverse momentum of partons in hadrons can also be gained. (orig.)

Behavioral Health and Performance Operations During the Space Shuttle Program

Science.gov (United States)

Beven, G.; Holland, A.; Moomaw, R.; Sipes, W.; Vander Ark, S.

2011-01-01

Prior to the Columbia STS 107 disaster in 2003, the Johnson Space Center s Behavioral Health and Performance Group (BHP) became involved in Space Shuttle Operations on an as needed basis, occasionally acting as a consultant and primarily addressing crew-crew personality conflicts. The BHP group also assisted with astronaut selection at every selection cycle beginning in 1991. Following STS 107, an event that spawned an increased need of behavioral health support to STS crew members and their dependents, BHP services to the Space Shuttle Program were enhanced beginning with the STS 114 Return to Flight mission in 2005. These services included the presence of BHP personnel at STS launches and landings for contingency support, a BHP briefing to the entire STS crew at L-11 months, a private preflight meeting with the STS Commander at L-9 months, and the presence of a BHP consultant at the L-1.5 month Family Support Office briefing to crew and family members. The later development of an annual behavioral health assessment of all active astronauts also augmented BHP s Space Shuttle Program specific services, allowing for private meetings with all STS crew members before and after each mission. The components of each facet of these BHP Space Shuttle Program support services will be presented, along with valuable lessons learned, and with recommendations for BHP involvement in future short duration space missions

When the proton becomes larger

CERN Multimedia

CERN Bulletin

2011-01-01

The TOTEM experiment at the LHC has just confirmed that, at high energy, protons behave as if they were becoming larger. In more technical terms, their total cross-section – a parameter linked to the proton-proton interaction probability – increases with energy. This phenomenon, expected from previous measurements performed at much lower energy, has now been confirmed for the first time at the LHC’s unprecedented energy.   One arm of a TOTEM T2 detector during its installation at interaction point 5. A composite particle like the proton is a complex system that in no way resembles a static Lego construction: sub-components move inside and interactions keep the whole thing together, but in a very dynamic way. This partly explains why even the very common proton can still be hiding secrets about its nature, decades after its discovery. One way of studying the inner properties of protons is to observe how they interact with each other, which, in technical terms, i...

Proton and carbon ion therapy

CERN Document Server

Lomax, Tony

2013-01-01

Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art...

Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling.

Science.gov (United States)

Zeng, Wei-Zheng; Liu, Di-Shi; Liu, Lu; She, Liang; Wu, Long-Jun; Xu, Tian-Le

2015-09-15

Extracellular transients of pH alterations likely mediate signal transduction in the nervous system. Neuronal acid-sensing ion channels (ASICs) act as sensors for extracellular protons, but the mechanism underlying ASIC activation remains largely unknown. Here, we show that, following activation of a light-activated proton pump, Archaerhodopsin-3 (Arch), proton transients induced ASIC currents in both neurons and HEK293T cells co-expressing ASIC1a channels. Using chimera proteins that bridge Arch and ASIC1a by a glycine/serine linker, we found that successful coupling occurred within 15 nm distance. Furthermore, two-cell sniffer patch recording revealed that regulated release of protons through either Arch or voltage-gated proton channel Hv1 activated neighbouring cells expressing ASIC1a channels. Finally, computational modelling predicted the peak proton concentration at the intercellular interface to be at pH 6.7, which is acidic enough to activate ASICs in vivo. Our results highlight the pathophysiological role of proton signalling in the nervous system.

New timetable for a Regular morning and evening shuttle

CERN Multimedia

TS Department

2008-01-01

Starting from 31 March 2008, for one month, a new timetable for a regular morning and evening shuttle serving LHC Points 2 and 5 will be put in place. You can find all the corresponding details on the FM group WEB page: http://ts-dep.web.cern.ch/ts-dep/groups/fm/logistique/shuttle_timetable.htm Please note that during April, all other requests for transport from Meyrin and Prévessin to the LHC Points via tel. 76969 during the day (between 8:30 and 17:30) will not be met. TS/FM group Tel. 160239

New timetable for a morning and evening regular shuttle

CERN Multimedia

TS Department

2008-01-01

Starting from the 31st of March 2008 and for one month, a new timetable for a morning and evening regular shuttle serving LHC Points 2 and 5, will be put in place. You can find all the corresponding details in the FM group WEB page http://ts-dep.web.cern.ch/ts-dep/groups/fm/logistique/shuttle_timetable.htm Please note that during April, every other request of transfer from Meyrin and Prevessin towards LHC Points reaching the 76969 during the day (between 8:30 and 17:30) will not be satisfied. TS/FM group 160239

Grooming the Shuttle for cost-effective access to space

Science.gov (United States)

Moore, J. W.

1985-01-01

An assessment is made of the performance of the Space Shuttle-based Space Transportation System (STS) from the initial flights in 1981 to the present, which has involved the launching of 12 satellites and the retrieval of two. It is expected that the STS will soon be able to schedule 24 routine missions/year, upon the achievement of full operational status for the full fleet of four Space Shuttles and the completion of support facilities at both the Kennedy Space Center and Vandenberg Air Force Base. The prospects for space industrialization efforts based on STS are noted.

ATLAS proton-proton event containing four muons

CERN Multimedia

ATLAS Collaboration

2011-01-01

An event with four identified muons from a proton-proton collision in ATLAS. This event is consistent with coming from two Z particles decaying: both Z particles decay to two muons each. Such events are produced by Standard Model processes without Higgs particles. They are also a possible signature for Higgs particle production, but many events must be analysed together in order to tell if there is a Higgs signal. This view is a zoom into the central part of the detector. The four muons are picked out as red tracks. Other tracks and deposits of energy in the calorimeters are shown in yellow.

Polarized proton collider at RHIC

International Nuclear Information System (INIS)

Alekseev, I.; Allgower, C.; Bai, M.; Batygin, Y.; Bozano, L.; Brown, K.; Bunce, G.; Cameron, P.; Courant, E.; Erin, S.; Escallier, J.; Fischer, W.; Gupta, R.; Hatanaka, K.; Huang, H.; Imai, K.; Ishihara, M.; Jain, A.; Lehrach, A.; Kanavets, V.; Katayama, T.; Kawaguchi, T.; Kelly, E.; Kurita, K.; Lee, S.Y.; Luccio, A.; MacKay, W.W.; Mahler, G.; Makdisi, Y.; Mariam, F.; McGahern, W.; Morgan, G.; Muratore, J.; Okamura, M.; Peggs, S.; Pilat, F.; Ptitsin, V.; Ratner, L.; Roser, T.; Saito, N.; Satoh, H.; Shatunov, Y.; Spinka, H.; Syphers, M.; Tepikian, S.; Tominaka, T.; Tsoupas, N.; Underwood, D.; Vasiliev, A.; Wanderer, P.; Willen, E.; Wu, H.; Yokosawa, A.; Zelenski, A.N.

2003-01-01

In addition to heavy ion collisions (RHIC Design Manual, Brookhaven National Laboratory), RHIC will also collide intense beams of polarized protons (I. Alekseev, et al., Design Manual Polarized Proton Collider at RHIC, Brookhaven National Laboratory, 1998, reaching transverse energies where the protons scatter as beams of polarized quarks and gluons. The study of high energy polarized protons beams has been a long term part of the program at BNL with the development of polarized beams in the Booster and AGS rings for fixed target experiments. We have extended this capability to the RHIC machine. In this paper we describe the design and methods for achieving collisions of both longitudinal and transverse polarized protons in RHIC at energies up to √s=500 GeV

Proton Radiography (pRad)

Data.gov (United States)

Federal Laboratory Consortium — The proton radiography project has used 800 MeV protons provided by the LANSCE accelerator facility at LANL, to diagnose more than 300 dynamic experiments in support...

Comparison of dynamical aspects of nonadiabatic electron, proton, and proton-coupled electron transfer reactions

International Nuclear Information System (INIS)

Hatcher, Elizabeth; Soudackov, Alexander; Hammes-Schiffer, Sharon

2005-01-01

The dynamical aspects of a model proton-coupled electron transfer (PCET) reaction in solution are analyzed with molecular dynamics simulations. The rate for nonadiabatic PCET is expressed in terms of a time-dependent probability flux correlation function. The impact of the proton donor-acceptor and solvent dynamics on the probability flux is examined. The dynamical behavior of the probability flux correlation function is dominated by a solvent damping term that depends on the energy gap correlation function. The proton donor-acceptor motion does not impact the dynamical behavior of the probability flux correlation function but does influence the magnitude of the rate. The approximations previously invoked for the calculation of PCET rates are tested. The effects of solvent damping on the proton donor-acceptor vibrational motion are found to be negligible, and the short-time solvent approximation, in which only equilibrium fluctuations of the solvent are considered, is determined to be valid for these types of reactions. The analysis of PCET reactions is compared to previous analyses of single electron and proton transfer reactions. The dynamical behavior is qualitatively similar for all three types of reactions, but the time scale of the decay of the probability flux correlation function is significantly longer for single proton transfer than for PCET and single electron transfer due to a smaller solvent reorganization energy for proton transfer

Proton Conductivity of Proton Exchange Membrane Synergistically Promoted by Different Functionalized Metal-Organic Frameworks.

Science.gov (United States)

Rao, Zhuang; Tang, Beibei; Wu, Peiyi

2017-07-12

In this study, two functionalized metal-organic frameworks (MOFs), UiO-66-SO 3 H and UiO-66-NH 2 , were synthesized. Then, different composite proton exchange membranes (PEMs) were prepared by single doping and codoping of these two MOFs, respectively. It was found that codoping of these two MOFs with suitable sizes was more conducive to the proton conductivity enhancement of the composite PEM. A synergistic effect between these two MOFs led to the the formation of more consecutive hydration channels in the composite PEM. It further greatly promoted the proton conductivity of the composite PEM. The proton conductivity of the codoped PEM reached up to 0.256 S/cm under 90 °C, 95% RH, which was ∼1.17 times higher than that of the recast Nafion (0.118 S/cm). Besides, the methanol permeability of the codoped PEM was prominently decreased owing to the methanol trapping effect of the pores of these two MOFs. Meanwhile, the high water and thermal stabilities of these two MOFs were beneficial to the high proton conductivity stability of the codoped PEM under high humidity and high temperature. The proton conductivity of the codoped PEM was almost unchanged throughout 3000 min of testing under 90 °C, 95% RH. This work provides a valuable reference for designing different functionalized MOFs to synergistically promote the proton conductivities of PEMs.

Proton radioactivity: the case for {sup 53m} Co proton-emitter isomer

Energy Technology Data Exchange (ETDEWEB)

Tavares, O.A.P.; Medeiros, E.L., E-mail: emil@cbpf.b

2010-07-01

The partial proton emission half-life for {sup 53m}Co unstable isomer is re-examined in the framework of a semiempirical model based on tunneling through a Coulomb-plus centrifugal- plus-overlapping potential barrier within the spherical nucleus approximation. It is shown that the known measured half-life value of 17 s is compatible with a large prolate shape for {sup 53m}Co proton emitter and a high angular momentum {iota} = 11 assigned to the proton transition to the ground-state of {sup 52}Fe. (author)

Proton radiography using highpower femtosecond laser

International Nuclear Information System (INIS)

Choi, Chang Il

2010-08-01

A femtosecond laser emits pulses whose width is between few and few hundreds femtoseconds (10 -15 s). The production mechanism of the high energy protons generated by the femtosecond laser is not clear so far, but the technologies have been improving. The applications using the generated protons are the proton therapy, proton radiography, nuclear physics, security inspection, and so on. Especially in the radiography, the laser-generated protons are very useful to obtain high quality images of thin objects, because protons are able to penetrate an object following an almost straight path and give a depth distribution information of various elements in a subject. Since the laser-driven protons require lower cost and smaller facility than accelerator-based protons, the radiography using laser-driven protons have been of interest. In this research, we have performed the radiography experiments by using protons generated by the 100 TW titanium sapphire femtosecond laser facility of Advanced Photonics Research Institute (APRI) of Gwangju Institute of Science Technology (GIST). A CR-39 Solid State Nuclear Track Detector (SSNTD) has been used as radiography screen. The radiography digital images have been obtained by using an optical microscope and a CCD camera. Modulation Transfer Function (MTF) has been derived from analyzing the obtained images, and the spatial resolution of the images have been evaluated. And, we have performed the radiography experiments of monoenergetic proton from the Tandem Van de Graaff accelerator of Korea Institute of Geoscience and Mineral Resources (KIGAM). We have obtained and compared the radiography images from other proton production methods which are the laser and the accelerator, respectively. And also, we have found out the optimized chemical etching condition, in order to improve the spatial resolution of the radiography images. Finally, the evaluated maximum spatial resolution of the images are 2.09 μm

Proton energy and scattering angle radiographs to improve proton treatment planning : a Monte Carlo study

NARCIS (Netherlands)

Biegun, Aleksandra; Takatsu, Jun; Nakaji, Taku; van Goethem, Marc-Jan; van der Graaf, Emiel; Koffeman, E.; Visser, Jan; Brandenburg, Sijtze

2016-01-01

The novel proton radiography imaging technique has a large potential to be used in direct measurement of the proton energy loss (proton stopping power, PSP) in various tissues in the patient. The uncertainty of PSPs, currently obtained from translation of X-ray Computed Tomography (xCT) images,

Experimental and theoretical study of two-proton and proton-deuteron correlations at very small relative momenta

International Nuclear Information System (INIS)

Martin, Lilian

1993-01-01

In this research thesis, the author first reports the analysis of light particle correlations by two theoretical approaches. The first one is the classical approximation of correlations: formulation, characteristics of the emitter nucleus and initial conditions, construction of the correlation function with notably the comparison with experimental proton-proton and proton-deuteron correlation functions measured in the 40 Ar + 108 Ag at 44 MeV/nucleon. The second one is the quantum approach of correlations: formulations, predictions of the quantum model with the same comparison as above. The second part addresses the measurement and analysis of the proton-proton correlation function at very small relative momenta: presentation of the studied reaction, description of the experiment (sensors, magnetic spectrometer, event recording), analysis of protons detected within the spectrometer) [fr

Shuttle Lesson Learned - Toxicology

Science.gov (United States)

James, John T.

2010-01-01

This is a script for a video about toxicology and the space shuttle. The first segment is deals with dust in the space vehicle. The next segment will be about archival samples. Then we'll look at real time on-board analyzers that give us a lot of capability in terms of monitoring for combustion products and the ability to monitor volatile organics on the station. Finally we will look at other issues that are about setting limits and dealing with ground based lessons that pertain to toxicology.

Influence of proton scattering angles on the energy radiograph in proton radiotherapy : A simulation study

NARCIS (Netherlands)

Biegun, A.K.; Takatsu, J.; van Beuzekom, M.; van der Graaf, E.R.; van Goethem, M-J.; Klaver, T.; Visser, J.; Brandenburg, S.

2015-01-01

The treatment quality of cancer patients with a proton beam critically depends on accurate predictions of proton stopping powers. Uncertainties in proton range that occur from translation of an X-ray CT patient image, of typical 3–4% or more, lead to necessary enlargements of contours around the

Correlation between the pionization region and the fragmentation region in high energy proton-proton collisions

CERN Document Server

Albrow, M G; Barber, D P; Bogaerts, A; Bosnjakovic, B; Brooks, J R; Clegg, A B; Erné, F C; Gee, C N P; Locke, D H; Loebinger, F K; Murphy, P G; Rudge, A; Sens, Johannes C

1973-01-01

Measurements are reported of two-particle correlations in high energy proton-proton collisions with one particle in the pionization region and the other a proton in the fragmentation region. The correlation function is independent of x of the fragmentation proton for 0.55

Deep-inelastic electron-proton diffraction

International Nuclear Information System (INIS)

Dainton, J.B.

1995-11-01

Recent measurements by the H1 collaboration at HERA of the cross section for deep-inelastic electron-proton scattering in which the proton interacts with minimal energy transfer and limited 4-momentum transfer squared are presented in the form of the contribution F 2 D(3) to the proton structure function F 2 . By parametrising the cross section phenomenologically in terms of a leading effective Regge pole exchange and comparing the result with a similar parametrisation of hadronic pp physics, the proton interaction is demonstrated to be dominantly of a diffractive nature. The quantitative interpretation of the parametrisation in terms of the properties of an effective leading Regge pole exchange, the pomeron (IP), shows that there is no evidence for a 'harder' BFKL-motivated IP in such deep-inelastic proton diffraction. The total contribution of proton diffraction to deep-inelastic electron-proton scattering is measured to be ∝10% and to be rather insensitive to Bjorken-x and Q 2 . A first measurement of the partonic structure of diffractive exchange is presented. It is shown to be readily interpreted in terms of the exchange of gluons, and to suggest that the bulk of diffractive momentum transfer is carried by a leading gluon. (orig.)

Platelet injectors for Space Shuttle orbit maneuvering engine

Science.gov (United States)

Kahl, R. C.; Labotz, R. J.; Bassham, L. B.

1974-01-01

The Space Shuttle Orbit Maneuvering Subsystem Rocket Engine employs a platelet element injector concept. This injector has demonstrated 316-sec vacuum specific impulse performance under simulated altitude conditions when tested with a milled slot/electroformed nickel close-out regenerative chamber and a full 71 area ratio nozzle. To date, over 300 altitude engine tests and 300 stability bomb tests have demonstrated stable, erosion free operation with this concept to test durations of 150 seconds. The injector and chamber also meet the reusable requirements of the shuttle with a cycle life capability in excess of 1000 cycles. An extensive altitude restart program has also demonstrated OMS-engine operation over large variations in the burn and coast times with helium saturated propellants.

A Shuttle Upper Atmosphere Mass Spectrometer /SUMS/ experiment

Science.gov (United States)

Blanchard, R. C.; Duckett, R. J.; Hinson, E. W.

1982-01-01

A magnetic mass spectrometer is currently being adapted to the Space Shuttle Orbiter to provide repeated high altitude atmosphere data to support in situ rarefied flow aerodynamics research, i.e., in the high velocity, low density flight regime. The experiment, called Shuttle Upper Atmosphere Mass Spectrometer (SUMS), is the first attempt to design mass spectrometer equipment for flight vehicle aerodynamic data extraction. The SUMS experiment will provide total freestream atmospheric quantitites, principally total mass density, above altitudes at which conventional pressure measurements are valid. Experiment concepts, the expected flight profile, tradeoffs in the design of the total system and flight data reduction plans are discussed. Development plans are based upon a SUMS first flight after the Orbiter initial development flights.

Flight results of attitude matching between Space Shuttle and Inertial Upper Stage (IUS) navigation systems

Science.gov (United States)

Treder, Alfred J.; Meldahl, Keith L.

The recorded histories of Shuttle/Orbiter attitude and Inertial Upper Stage (IUS) attitude have been analyzed for all joint flights of the IUS in the Orbiter. This database was studied to determine the behavior of relative alignment between the IUS and Shuttle navigation systems. It is found that the overall accuracy of physical alignment has a Shuttle Orbiter bias component less than 5 arcmin/axis and a short-term stability upper bound of 0.5 arcmin/axis, both at 1 sigma. Summaries of the experienced physical and inertial alginment offsets are shown in this paper, together with alignment variation data, illustrated with some flight histories. Also included is a table of candidate values for some error source groups in an Orbiter/IUS attitude errror model. Experience indicates that the Shuttle is much more accurate and stable as an orbiting launch platform than has so far been advertised. This information will be valuable for future Shuttle payloads, especially those (such as the Aeroassisted Flight Experiment) which carry their own inertial navigation systems, and which could update or initialize their attitude determination systems using the Shuttle as the reference.

Study of proton and 2 protons emission from light neutron deficient nuclei around A=20; Etude de l'emission proton et de deux protons dans les noyaux legers deficients en neutrons de la region A=20

Energy Technology Data Exchange (ETDEWEB)

Zerguerras, T

2001-09-01

Proton and two proton emission from light neutron deficient nuclei around A=20 have been studied. A radioactive beam of {sup 18}Ne, {sup 17}F and {sup 20}Mg, produced at the Grand Accelerateur National d'Ions Lourds by fragmentation of a {sup 24}Mg primary beam at 95 MeV/A, bombarded a {sup 9}Be target to form unbound states. Proton(s) and nuclei from the decay were detected respectively in the MUST array and the SPEG spectrometer. From energy and angle measurements, the invariant mass of the decaying nucleus could be reconstructed. Double coincidence events between a proton and {sup 17}F, {sup 16}O, {sup 15}O, {sup 14}O and {sup 18}Ne were registered to obtain excitation energy spectra of {sup 18}Ne, {sup 17}F, {sup 16}F, {sup 15}F et {sup 19}Na. Generally, the masses measures are in agreement with previous experiments. In the case of {sup 18}Ne, excitation energy and angular distributions agree well with the predictions of a break up model calculation. From {sup 17}Ne proton coincidences, a first experimental measurement of the ground state mass excess of {sup 18}Na has been obtained and yields 24,19(0,15)MeV. Two proton emission from {sup 17}Ne and {sup 18}Ne excited states and the {sup 19}Mg ground state was studied through triple coincidences between two proton and {sup 15}O, {sup 16}O and {sup 17}Ne respectively. In the first case, the proton-proton relative angle distribution in the center of mass has been compared with model calculation. Sequential emission from excited states of {sup 17}Ne, above the proton emission threshold, through {sup 16}F is dominant but a {sup 2}He decay channel could not be excluded. No {sup 2}He emission from the 1.288 MeV {sup 17}Ne state, or from the 6.15 MeV {sup 18}Ne state has been observed. Only one coincidence event between {sup 17}Ne and two proton was registered, the value of the one neutron stripping reaction cross section of {sup 20}Mg being much lower than predicted. (author)

ACTS/TOS after release from Shuttle Discovery

Science.gov (United States)

1993-01-01

The Advanced Communications Technology Satellite (ACTS) with its Transfer Orbit Stage (TOS) is backdropped over the blue ocean following its release from the Earth-orbiting Space Shuttle Discovery. ACTS/TOS deploy was the first major task performed on the almost ten-day mission.

ACCELERATION OF POLARIZED PROTONS AT RHIC

International Nuclear Information System (INIS)

HUANG, H.

2002-01-01

Relativistic Heavy Ion Collider (RHIC) ended its second year of operation in January 2002 with five weeks of polarized proton collisions. Polarized protons were successfully injected in both RHIC rings and maintained polarization during acceleration up to 100 GeV per ring using two Siberian snakes in each ring. This is the first time that polarized protons have been accelerated to 100 GeV. The machine performance and accomplishments during the polarized proton run will be reviewed. The plans for the next polarized proton run will be outlined

Characterization of Space Shuttle Thermal Protection System (TPS) Materials for Return-to-Flight following the Shuttle Columbia Accident Investigation

Science.gov (United States)

Wingard, Doug

2006-01-01

During the Space Shuttle Columbia Accident Investigation, it was determined that a large chunk of polyurethane insulating foam (= 1.67 lbs) on the External Tank (ET) came loose during Columbia's ascent on 2-1-03. The foam piece struck some of the protective Reinforced Carbon-Carbon (RCC) panels on the leading edge of Columbia's left wing in the mid-wing area. This impact damaged Columbia to the extent that upon re-entry to Earth, superheGed air approaching 3,000 F caused the vehicle to break up, killing all seven astronauts on board. A paper after the Columbia Accident Investigation highlighted thermal analysis testing performed on External Tank TPS materials (1). These materials included BX-250 (now BX-265) rigid polyurethane foam and SLA-561 Super Lightweight Ablator (highly-filled silicone rubber). The large chunk of foam from Columbia originated fiom the left bipod ramp of the ET. The foam in this ramp area was hand-sprayed over the SLA material and various fittings, allowed to dry, and manually shaved into a ramp shape. In Return-to-Flight (RTF) efforts following Columbia, the decision was made to remove the foam in the bipod ramp areas. During RTF efforts, further thermal analysis testing was performed on BX-265 foam by DSC and DMA. Flat panels of foam about 2-in. thick were sprayed on ET tank material (aluminum alloys). The DSC testing showed that foam material very close to the metal substrate cured more slowly than bulk foam material. All of the foam used on the ET is considered fully cured about 21 days after it is sprayed. The RTF culminated in the successful launch of Space Shuttle Discovery on 7-26-05. Although the flight was a success, there was another serious incident of foam loss fiom the ET during Shuttle ascent. This time, a rather large chunk of BX-265 foam (= 0.9 lbs) came loose from the liquid hydrogen (LH2) PAL ramp, although the foam did not strike the Shuttle Orbiter containing the crew. DMA testing was performed on foam samples taken fiom

Structural Continuum Modeling of Space Shuttle External Tank Foam Insulation

Science.gov (United States)

Steeve, Brian; Ayala, Sam; Purlee, T. Eric; Shaw, Phillip

2006-01-01

This document is a viewgraph presentation reporting on work in modeling the foam insulation of the Space Shuttle External Tank. An analytical understanding of foam mechanics is required to design against structural failure. The Space Shuttle External Tank is covered primarily with closed cell foam to: Prevent ice, Protect structure from ascent aerodynamic and engine plume heating, and Delay break-up during re-entry. It is important that the foam does not shed unacceptable debris during ascent environment. Therefore a modeling of the foam insulation was undertaken.

Apparatus for proton radiography

International Nuclear Information System (INIS)

Martin, R.L.

1976-01-01

An apparatus for effecting diagnostic proton radiography of patients in hospitals comprises a source of negative hydrogen ions, a synchrotron for accelerating the negative hydrogen ions to a predetermined energy, a plurality of stations for stripping extraction of a radiography beam of protons, means for sweeping the extracted beam to cover a target, and means for measuring the residual range, residual energy, or percentage transmission of protons that pass through the target. The combination of information identifying the position of the beam with information about particles traversing the subject and the back absorber is performed with the aid of a computer to provide a proton radiograph of the subject. In an alternate embodiment of the invention, a back absorber comprises a plurality of scintillators which are coupled to detectors. 10 claims, 7 drawing figures

Measurement of the analysing power of elastic proton-proton scattering at 582 MeV

International Nuclear Information System (INIS)

Berdoz, A.; Favier, B.; Foroughi, F.; Weddigen, C.

1984-01-01

The authors have measured the analysing power of elastic proton-proton scattering at 582 MeV for 14 angles from 20 to 80 0 CM. The angular range was limited to >20 0 by the energy loss of the recoil protons. The experiment was performed at the PM1 beam line at SIN. A beam intensity of about 10 8 particles s -1 was used. (Auth.)

Sodium and Proton Effects on Inward Proton Transport through Na/K Pumps

Science.gov (United States)

Mitchell, Travis J.; Zugarramurdi, Camila; Olivera, J. Fernando; Gatto, Craig; Artigas, Pablo

2014-01-01

The Na/K pump hydrolyzes ATP to export three intracellular Na (Nai) as it imports two extracellular K (Ko) across animal plasma membranes. Within the protein, two ion-binding sites (sites I and II) can reciprocally bind Na or K, but a third site (site III) exclusively binds Na in a voltage-dependent fashion. In the absence of Nao and Ko, the pump passively imports protons, generating an inward current (IH). To elucidate the mechanisms of IH, we used voltage-clamp techniques to investigate the [H]o, [Na]o, and voltage dependence of IH in Na/K pumps from ventricular myocytes and in ouabain-resistant pumps expressed in Xenopus oocytes. Lowering pHo revealed that Ho both activates IH (in a voltage-dependent manner) and inhibits it (in a voltage-independent manner) by binding to different sites. Nao effects depend on pHo; at pHo where no Ho inhibition is observed, Nao inhibits IH at all concentrations, but when applied at pHo that inhibits pump-mediated current, low [Na]o activates IH and high [Na]o inhibits it. Our results demonstrate that IH is a property inherent to Na/K pumps, not linked to the oocyte expression environment, explains differences in the characteristics of IH previously reported in the literature, and supports a model in which 1), protons leak through site III; 2), binding of two Na or two protons to sites I and II inhibits proton transport; and 3), pumps with mixed Na/proton occupancy of sites I and II remain permeable to protons. PMID:24940773

Quality verification for respiratory gated proton therapy

International Nuclear Information System (INIS)

Kim, Eun Sook; Jang, Yo Jong; Park, Ji Yeon; Kang, Dong Yun; Yeom, Doo Seok

2013-01-01

To verify accuracy of respiratory gated proton therapy by measuring and analyzing proton beam delivered when respiratory gated proton therapy is being performed in our institute. The plan data of 3 patients who took respiratory gated proton therapy were used to deliver proton beam from proton therapy system. The manufactured moving phantom was used to apply respiratory gating system to reproduce proton beam which was partially irradiated. The key characteristics of proton beam, range, spreat-out Bragg peak (SOBP) and output factor were measured 5 times and the same categories were measured in the continuous proton beam which was not performed with respiratory gating system. Multi-layer ionization chamber was used to measure range and SOBP, and Scanditronix Wellhofer and farmer chamber was used to measure output factor. The average ranges of 3 patients (A, B, C), who had taken respiratory gated proton therapy or not, were (A) 7.226, 7.230, (B) 12.216, 12.220 and (C) 19.918, 19.920 g/cm 2 and average SOBP were (A) 4.950, 4.940, (B) 6.496, 6.512 and (C) 8.486, 8.490 g/cm 2 . And average output factor were (A) 0.985, 0.984 (B) 1.026, 1.027 and (C) 1.138, 1.136 cGy/MU. The differences of average range were -0.004, -0.004, -0.002 g/cm 2 , that of SOBP were 0.010, -0.016, -0.004 g/cm 2 and that of output factor were 0.001, -0.001, 0.002 cGy/MU. It is observed that the range, SOBP and output factor of proton beam delivered when respiratory gated proton therapy is being performed have the same beam quality with no significant difference compared to the proton beam which was continuously irradiated. Therefore, this study verified the quality of proton beam delivered when respiratory gated proton therapy and confirmed the accuracy of proton therapy using this

Space Shuttle Program Primary Avionics Software System (PASS) Success Legacy - Quality and Reliability Date

Science.gov (United States)

Orr, James K.; Peltier, Daryl

2010-01-01

Thsi slide presentation reviews the avionics software system on board the space shuttle, with particular emphasis on the quality and reliability. The Primary Avionics Software System (PASS) provides automatic and fly-by-wire control of critical shuttle systems which executes in redundant computers. Charts given show the number of space shuttle flights vs time, PASS's development history, and other charts that point to the reliability of the system's development. The reliability of the system is also compared to predicted reliability.

A self-discharge model of Lithium-Sulfur batteries based on direct shuttle current measurement

DEFF Research Database (Denmark)

Knap, Vaclav; Stroe, Daniel Loan; Swierczynski, Maciej Jozef

2016-01-01

. A simple but comprehensive mathematical model of the Li-S battery cell self-discharge based on the shuttle current was developed and is presented. The shuttle current values for the model parameterization were obtained from the direct shuttle current measurements. Furthermore, the battery cell depth......-of-discharge values were recomputed in order to account for the influence of the self-discharge and provide a higher accuracy of the model. Finally, the derived model was successfully validated against laboratory experiments at various conditions....

Hubble Servicing Challenges Drive Innovation of Shuttle Rendezvous Techniques

Science.gov (United States)

Goodman, John L.; Walker, Stephen R.

2009-01-01

Hubble Space Telescope (HST) servicing, performed by Space Shuttle crews, has contributed to what is arguably one of the most successful astronomy missions ever flown. Both nominal and contingency proximity operations techniques were developed to enable successful servicing, while lowering the risk of damage to HST systems, and improve crew safety. Influencing the development of these techniques were the challenges presented by plume impingement and HST performance anomalies. The design of both the HST and the Space Shuttle was completed before the potential of HST contamination and structural damage by shuttle RCS jet plume impingement was fully understood. Relative navigation during proximity operations has been challenging, as HST was not equipped with relative navigation aids. Since HST reached orbit in 1990, proximity operations design for servicing missions has evolved as insight into plume contamination and dynamic pressure has improved and new relative navigation tools have become available. Servicing missions have provided NASA with opportunities to gain insight into servicing mission design and development of nominal and contingency procedures. The HST servicing experiences and lessons learned are applicable to other programs that perform on-orbit servicing and rendezvous, both human and robotic.

Space Shuttle Atlantis is on Launch Pad 39B

Science.gov (United States)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Atop the mobile launcher platform, Space Shuttle Atlantis arrives on Launch Pad 39B after rollout from the Vehicle Assembly Building. Seen on either side of the orbiters tail are the tail service masts. They support the fluid, gas and electrical requirements of the orbiters liquid oxygen and liquid hydrogen aft umbilicals. The Shuttle is targeted for launch no earlier than July 12 on mission STS-104, the 10th flight to the International Space Station. The payload on the 11- day mission is the Joint Airlock Module, which will allow astronauts and cosmonauts in residence on the Station to perform future spacewalks without the presence of a Space Shuttle. The module, which comprises a crew lock and an equipment lock, will be connected to the starboard (right) side of Node 1 Unity. Atlantis will also carry oxygen and nitrogen storage tanks, vital to operation of the Joint Airlock, on a Spacelab Logistics Double Pallet in the payload bay. The tanks, to be installed on the perimeter of the Joint Module during the missions spacewalks, will support future spacewalk operations and experiments plus augment the resupply system for the Stations Service Module.

Shuttling single metal atom into and out of a metal nanoparticle.

Science.gov (United States)

Wang, Shuxin; Abroshan, Hadi; Liu, Chong; Luo, Tian-Yi; Zhu, Manzhou; Kim, Hyung J; Rosi, Nathaniel L; Jin, Rongchao

2017-10-10

It has long been a challenge to dope metal nanoparticles with a specific number of heterometal atoms at specific positions. This becomes even more challenging if the heterometal belongs to the same group as the host metal because of the high tendency of forming a distribution of alloy nanoparticles with different numbers of dopants due to the similarities of metals in outmost electron configuration. Herein we report a new strategy for shuttling a single Ag or Cu atom into a centrally hollow, rod-shaped Au 24 nanoparticle, forming AgAu 24 and CuAu 24 nanoparticles in a highly controllable manner. Through a combined approach of experiment and theory, we explain the shuttling pathways of single dopants into and out of the nanoparticles. This study shows that the single dopant is shuttled into the hollow Au 24 nanoparticle either through the apex or side entry, while shuttling a metal atom out of the Au 25 to form the Au 24 nanoparticle occurs mainly through the side entry.Doping a metal nanocluster with heteroatoms dramatically changes its properties, but it remains difficult to dope with single-atom control. Here, the authors devise a strategy to dope single atoms of Ag or Cu into hollow Au nanoclusters, creating precise alloy nanoparticles atom-by-atom.

Proton emission from high spin states of proton rich excited 94Ag

International Nuclear Information System (INIS)

Aggarwal, Mamta

2008-01-01

Recent observation of direct 1P and 2P decay of 21 + isomer in proton rich 94 Ag has led to the present theoretical investigation of proton radioactivity from 94 Ag in ground state and excited state and it's dependence on the structural transitions

WE-D-BRB-00: Basics of Proton Therapy

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

The goal of this session is to review the physics of proton therapy, treatment planning techniques, and the use of volumetric imaging in proton therapy. The course material covers the physics of proton interaction with matter and physical characteristics of clinical proton beams. It will provide information on proton delivery systems and beam delivery techniques for double scattering (DS), uniform scanning (US), and pencil beam scanning (PBS). The session covers the treatment planning strategies used in DS, US, and PBS for various anatomical sites, methods to address uncertainties in proton therapy and uncertainty mitigation to generate robust treatment plans. It introduces the audience to the current status of image guided proton therapy and clinical applications of CBCT for proton therapy. It outlines the importance of volumetric imaging in proton therapy. Learning Objectives: Gain knowledge in proton therapy physics, and treatment planning for proton therapy including intensity modulated proton therapy. The current state of volumetric image guidance equipment in proton therapy. Clinical applications of CBCT and its advantage over orthogonal imaging for proton therapy. B. Teo, B.K Teo had received travel funds from IBA in 2015.

WE-D-BRB-00: Basics of Proton Therapy

International Nuclear Information System (INIS)

2016-01-01

The goal of this session is to review the physics of proton therapy, treatment planning techniques, and the use of volumetric imaging in proton therapy. The course material covers the physics of proton interaction with matter and physical characteristics of clinical proton beams. It will provide information on proton delivery systems and beam delivery techniques for double scattering (DS), uniform scanning (US), and pencil beam scanning (PBS). The session covers the treatment planning strategies used in DS, US, and PBS for various anatomical sites, methods to address uncertainties in proton therapy and uncertainty mitigation to generate robust treatment plans. It introduces the audience to the current status of image guided proton therapy and clinical applications of CBCT for proton therapy. It outlines the importance of volumetric imaging in proton therapy. Learning Objectives: Gain knowledge in proton therapy physics, and treatment planning for proton therapy including intensity modulated proton therapy. The current state of volumetric image guidance equipment in proton therapy. Clinical applications of CBCT and its advantage over orthogonal imaging for proton therapy. B. Teo, B.K Teo had received travel funds from IBA in 2015.

Golden Jubilee photos: ISR - The first proton-proton interactions

CERN Document Server

2004-01-01

At the inauguration ceremony for the Intersecting Storage Rings (ISR) on 16 October 1971, the man in charge of their construction, Kjell Johnsen, presented the "key" to the machine to Edoardo Amaldi, President of Council. Seated on the stage with them for this symbolic event were Victor Weisskopf, Marcel Antonioz, Willy Jentschke (seen on the left of the photo) and Werner Heisenberg (on the far right). On 27 January that year, in a world premier, signals produced by proton-proton collisions had been observed at the ISR. The protons, supplied by the PS, were injected into two identical rings, each measuring 300 metres in diameter, and collided head on at the 8 points where the rings intersected. The installation, which remained in operation until 1984, gave physicists access to a wide range of energies for hadron physics, hitherto restricted to the data from cosmic ray studies. The many technological challenges that were met at the ISR, in the fields of vacuum technology and stochastic cooling for instance,...

Space Shuttle Orbiter logistics - Managing in a dynamic environment

Science.gov (United States)

Renfroe, Michael B.; Bradshaw, Kimberly

1990-01-01

The importance and methods of monitoring logistics vital signs, logistics data sources and acquisition, and converting data into useful management information are presented. With the launch and landing site for the Shuttle Orbiter project at the Kennedy Space Center now totally responsible for its own supportability posture, it is imperative that logistics resource requirements and management be continually monitored and reassessed. Detailed graphs and data concerning various aspects of logistics activities including objectives, inventory operating levels, customer environment, and data sources are provided. Finally, some lessons learned from the Shuttle Orbiter project and logistics options which should be considered by other space programs are discussed.

PEMBELAJARAN LARI CEPAT DENGAN MENGGUNAKAN MODIFIKASI SHUTTLE RUN

Directory of Open Access Journals (Sweden)

Suharjo

2015-09-01

Full Text Available The purpose of this study was to determine "Is Modified Shuttle Run can improve learning outcomes Elementary School fifth grade students Cenggini 02 Subdistrict Balapulang Tegal 2014". This research method is a class action research by using two cycles, each cycle consisting of four stages, namely planning, tindakkan, observation and action planning refleksi..Pada second cycle associated with the results achieved in the first cycle acts as an improvement efforts of the cycle. The subjects of this study were fifth grade students of elementary Negri Cenggini 02. Research conducted includes three domains, namely affective, cognitive and psychomotor addition to the observations made during the process of the learning process takes place. The results showed the affective, cognitive and psychomotor well categorized shows that the learning outcomes quick run using a modified shuttle run a positive impact as seen on mastery learning outcomes of students who exceed the predetermined KKM 75 In the first cycle the average value of students 75 , 71 in the second cycle the average value of 78.60 students, mastery learning in the first cycle reaches 64.29%, while in the second cycle reaches 92.86% mastery learning .mean mastery learning students has increased by 28.57%. It is concluded that learning to run faster by using a modified shuttle run has a positive effect, which can increase student interest and motivation to learn.

Optimization of Proton CT Detector System and Image Reconstruction Algorithm for On-Line Proton Therapy.

Directory of Open Access Journals (Sweden)

Chae Young Lee

Full Text Available The purposes of this study were to optimize a proton computed tomography system (pCT for proton range verification and to confirm the pCT image reconstruction algorithm based on projection images generated with optimized parameters. For this purpose, we developed a new pCT scanner using the Geometry and Tracking (GEANT 4.9.6 simulation toolkit. GEANT4 simulations were performed to optimize the geometric parameters representing the detector thickness and the distance between the detectors for pCT. The system consisted of four silicon strip detectors for particle tracking and a calorimeter to measure the residual energies of the individual protons. The optimized pCT system design was then adjusted to ensure that the solution to a CS-based convex optimization problem would converge to yield the desired pCT images after a reasonable number of iterative corrections. In particular, we used a total variation-based formulation that has been useful in exploiting prior knowledge about the minimal variations of proton attenuation characteristics in the human body. Examinations performed using our CS algorithm showed that high-quality pCT images could be reconstructed using sets of 72 projections within 20 iterations and without any streaks or noise, which can be caused by under-sampling and proton starvation. Moreover, the images yielded by this CS algorithm were found to be of higher quality than those obtained using other reconstruction algorithms. The optimized pCT scanner system demonstrated the potential to perform high-quality pCT during on-line image-guided proton therapy, without increasing the imaging dose, by applying our CS based proton CT reconstruction algorithm. Further, we make our optimized detector system and CS-based proton CT reconstruction algorithm potentially useful in on-line proton therapy.

Proton therapy in Australia

International Nuclear Information System (INIS)

Jackson, M.

2000-01-01

Full text: Proton therapy has been in use since 1954 and over 25,000 patients have been treated worldwide. Until recently most patients were treated at physics research facilities but with the development of more compact and reliable accelerators it is now possible to realistically plan for proton therapy in an Australian hospital. The Australian National Proton Project has been formed to look at the feasibility of a facility which would be primarily for patient treatment but would also be suitable for research and commercial applications. A detailed report will be produced by the end of the year. The initial clinical experience was mainly with small tumours and other lesions close to critical organs. Large numbers of eye tumours have also been treated. Protons have a well-defined role in these situations and are now being used in the treatment of more common cancers. With the development of hospital-based facilities, over 2,500 patients with prostate cancer have been treated using a simple technique which gives results at least as good as radical surgery, external beam radiotherapy or brachytherapy. Importantly, the incidence of severe complications is very low. There are encouraging results in many disease sites including lung, liver, soft tissue sarcomas and oesophagus. As proton therapy becomes more widely available, randomised trials comparing it with conventional radiotherapy or Intensity Modulated Radiation Therapy (IMRT) will be possible. In most situations the use of protons will enable a higher dose to be given safely but in situations where local control rates are already satisfactory, protons are expected to produce less complications than conventional treatment. The initial costs of a proton facility are high but the recurrent costs are similar to other forms of high technology radiotherapy. . Simple treatment techniques with only a few fields are usually possible and proton therapy avoids the high integral doses associated with IMRT. This reduction in

Observation of correlation between two fast protons in proton-nucleus interactions at 640 MeV

International Nuclear Information System (INIS)

Komarov, V.I.; Kosarev, G.E.

1978-01-01

The measurements have been performed to observe correlations between backward emitted protons (BEP) and forward outgoing protons from quasi-free scattering of the incident proton of 640 MeV on a nucleons pair [pN] within Be, C, Al, Cu and Pb nucleus at the angles 12 deg and 122 deg: p 0 + pN → p 1 + N + p 3 . Here p 1 is a proton detected in coincidence with BEP p 3 and N is a nucleon unobserved under the conditions of this experiment. The differential cross sections for the BEP of energies from 50 to 145 MeV have been measured in coincidence with forward outgoing protons (255 to 330 MeV) by scintillation counter method. The inclusive BEP spectra have been explained by the quasi-elastic backscattering on clusters which do not break up during the interaction. The calculated distribution are remarkably narrower than the experimental anes. The measurements point out that the discussed production of two fast protons is observable with all the targets and the cross section per target nucleon decreases with increasing the target mass number

Multicavity proton cyclotron accelerator

Directory of Open Access Journals (Sweden)

J. L. Hirshfield

2002-08-01

Full Text Available A mechanism for acceleration of protons is described, in which energy gain occurs near cyclotron resonance as protons drift through a sequence of rotating-mode TE_{111} cylindrical cavities in a strong nearly uniform axial magnetic field. Cavity resonance frequencies decrease in sequence from one another with a fixed frequency interval Δf between cavities, so that synchronism can be maintained between the rf fields and proton bunches injected at intervals of 1/Δf. An example is presented in which a 122 mA, 1 MeV proton beam is accelerated to 961 MeV using a cascade of eight cavities in an 8.1 T magnetic field, with the first cavity resonant at 120 MHz and with Δf=8 MHz. Average acceleration gradient exceeds 40 MV/m, average effective shunt impedance is 223 MΩ/m, but maximum surface field in the cavities does not exceed 7.2 MV/m. These features occur because protons make many orbital turns in each cavity and thus experience acceleration from each cavity field many times. Longitudinal and transverse stability appear to be intrinsic properties of the acceleration mechanism, and an example to illustrate this is presented. This acceleration concept could be developed into a proton accelerator for a high-power neutron spallation source, such as that required for transmutation of nuclear waste or driving a subcritical fission burner, provided a number of significant practical issues can be addressed.

Space Shuttle: Human Capital Challenges Require Management Attention

National Research Council Canada - National Science Library

2000-01-01

.... NASA budget data shows that, since 1995, shuttle workforce levels have decreased from about 3,000 to about 1,800 full time equivalent employees NASA based its downsizing efforts on optimistic programmatic assumptions...

Space Shuttle Launch Probability Analysis: Understanding History so We Can Predict the Future

Science.gov (United States)

Cates, Grant R.

2014-01-01

The Space Shuttle was launched 135 times and nearly half of those launches required 2 or more launch attempts. The Space Shuttle launch countdown historical data of 250 launch attempts provides a wealth of data that is important to analyze for strictly historical purposes as well as for use in predicting future launch vehicle launch countdown performance. This paper provides a statistical analysis of all Space Shuttle launch attempts including the empirical probability of launch on any given attempt and the cumulative probability of launch relative to the planned launch date at the start of the initial launch countdown. This information can be used to facilitate launch probability predictions of future launch vehicles such as NASA's Space Shuttle derived SLS. Understanding the cumulative probability of launch is particularly important for missions to Mars since the launch opportunities are relatively short in duration and one must wait for 2 years before a subsequent attempt can begin.

Study of proton and 2 protons emission from light neutron deficient nuclei around A=20; Etude de l'emission proton et de deux protons dans les noyaux legers deficients en neutrons de la region A=20

Energy Technology Data Exchange (ETDEWEB)

Zerguerras, T

2001-09-01

Proton and two proton emission from light neutron deficient nuclei around A=20 have been studied. A radioactive beam of {sup 18}Ne, {sup 17}F and {sup 20}Mg, produced at the Grand Accelerateur National d'Ions Lourds by fragmentation of a {sup 24}Mg primary beam at 95 MeV/A, bombarded a {sup 9}Be target to form unbound states. Proton(s) and nuclei from the decay were detected respectively in the MUST array and the SPEG spectrometer. From energy and angle measurements, the invariant mass of the decaying nucleus could be reconstructed. Double coincidence events between a proton and {sup 17}F, {sup 16}O, {sup 15}O, {sup 14}O and {sup 18}Ne were registered to obtain excitation energy spectra of {sup 18}Ne, {sup 17}F, {sup 16}F, {sup 15}F et {sup 19}Na. Generally, the masses measures are in agreement with previous experiments. In the case of {sup 18}Ne, excitation energy and angular distributions agree well with the predictions of a break up model calculation. From {sup 17}Ne proton coincidences, a first experimental measurement of the ground state mass excess of {sup 18}Na has been obtained and yields 24,19(0,15)MeV. Two proton emission from {sup 17}Ne and {sup 18}Ne excited states and the {sup 19}Mg ground state was studied through triple coincidences between two proton and {sup 15}O, {sup 16}O and {sup 17}Ne respectively. In the first case, the proton-proton relative angle distribution in the center of mass has been compared with model calculation. Sequential emission from excited states of {sup 17}Ne, above the proton emission threshold, through {sup 16}F is dominant but a {sup 2}He decay channel could not be excluded. No {sup 2}He emission from the 1.288 MeV {sup 17}Ne state, or from the 6.15 MeV {sup 18}Ne state has been observed. Only one coincidence event between {sup 17}Ne and two proton was registered, the value of the one neutron stripping reaction cross section of {sup 20}Mg being much lower than predicted. (author)

ATLAS proton-proton event containing two high energy photons

CERN Multimedia

ATLAS Collaboration

2011-01-01

An event where two energetic photons ("gammas") are produced in a proton-proton collision in ATLAS. Many events of this type are produced by well-understood Standard Model processes ("backgrounds") which do not involve Higgs particles. A small excess of events of this type with similar masses could indicate evidence for Higgs particle production, but any specific event is most likely to be from the background. The photons are indicated, in the different projections and views, by the clusters of energy shown in yellow.

DOD Residential Proton Exchange Membrane (PEM) Fuel Cell Demonstration Program. Volume 2. Summary of Fiscal Year 2001-2003 Projects

Science.gov (United States)

2005-09-01

produced many of the Beatles 1970s recordings. This facility was selected to host the UK PEM demonstration project from a selection of four potential sites...funded the Department of Defense (DOD) Residential PEM Demonstration Project to demonstrate domestically-produced, residential Proton Exchange Membrane...PEM) fuel cells at DOD Facilities. The objectives were to: (1) assess PEM fuel cells’ role in supporting sustainability at military installations

Photometric analysis of a space shuttle water venting

Science.gov (United States)

Viereck, R. A.; Murad, E.; Pike, C. P.; Kofsky, I. L.; Trowbridge, C. A.; Rall, D. L. A.; Satayesh, A.; Berk, A.; Elgin, J. B.

1991-01-01

Presented here is a preliminary interpretation of a recent experiment conducted on Space Shuttle Discovery (Mission STS 29) in which a stream of liquid supply water was vented into space at twilight. The data consist of video images of the sunlight-scattering water/ice particle cloud that formed, taken by visible light-sensitive intensified cameras both onboard the spacecraft and at the AMOS ground station near the trajectory's nadir. This experiment was undertaken to study the phenomenology of water columns injected into the low-Earth orbital environment, and to provide information about the lifetime of ice particles that may recontact Space Shuttle orbits later. The findings about the composition of the cloud have relevance to ionospheric plasma depletion experiments and to the dynamics of the interaction of orbiting spacecraft with the environment.

Space Shuttle Program (SSP) Dual Docked Operations (DDO)

Science.gov (United States)

Sills, Joel W., Jr.; Bruno, Erica E.

2016-01-01

This document describes the concept definition, studies, and analysis results generated by the Space Shuttle Program (SSP), International Space Station (ISS) Program (ISSP), and Mission Operations Directorate for implementing Dual Docked Operations (DDO) during mated Orbiter/ISS missions. This work was performed over a number of years. Due to the ever increasing visiting vehicle traffic to and from the ISS, it became apparent to both the ISSP and the SSP that there would arise occasions where conflicts between a visiting vehicle docking and/or undocking could overlap with a planned Space Shuttle launch and/or during docked operations. This potential conflict provided the genesis for evaluating risk mitigations to gain maximum flexibility for managing potential visiting vehicle traffic to and from the ISS and to maximize launch and landing opportunities for all visiting vehicles.

Evaluation of anaerobic capacity in soccer players using a maximal shuttle run test

Directory of Open Access Journals (Sweden)

Alexandre Gomes de Almeida

2009-01-01

Full Text Available http://dx.doi.org/10.5007/1980-0037.2009v11n1p88   The aim of this study was to investigate whether a 300-m shuttle run test predicts anaerobic capacity, expressed as mean power output in the Wingate test, in a group of professional soccer players. Twenty-one soccer players (21 ± 2 years; 76.8 ± 7.0 kg; 179.8 ± 6.7 cm from a first division team of the São Paulo Soccer Federation participated in the study. In the first session, the players were submitted to the Wingate test for the determination of relative peak power output, relative mean power output and fatigue index. In the second session, the players underwent a shuttle run test which consisted of a maximum sprint of 20 m at the highest speed possible until completing a distance of 300 m. The total run time and mean velocity over the 20 m (V20m were recorded. Blood samples were collected before and after the 300-m shuttle run test for the determination of lactate concentration ([LAC]. Pearson’s correlation between the Wingate and 300-m shuttle run test variables showed that only relative mean power output was significantly correlated with total run time (r = - 0.75 and V20m (r = 0.72. [LAC] showed a significant increase (p < 0.05 when comparing the values obtained before (2.1 ± 1.0 mM and after (14.3 ± 2.4 mM the shuttle run test. In conclusion, this study demonstrated that the 300-m shuttle run test can predict anaerobic capacity in professional soccer players.

Space shuttle configuration accounting functional design specification

Science.gov (United States)

1974-01-01

An analysis is presented of the requirements for an on-line automated system which must be capable of tracking the status of requirements and engineering changes and of providing accurate and timely records. The functional design specification provides the definition, description, and character length of the required data elements and the interrelationship of data elements to adequately track, display, and report the status of active configuration changes. As changes to the space shuttle program levels II and III configuration are proposed, evaluated, and dispositioned, it is the function of the configuration management office to maintain records regarding changes to the baseline and to track and report the status of those changes. The configuration accounting system will consist of a combination of computers, computer terminals, software, and procedures, all of which are designed to store, retrieve, display, and process information required to track proposed and proved engineering changes to maintain baseline documentation of the space shuttle program levels II and III.

Study of the proton-proton interaction involving a πO production

International Nuclear Information System (INIS)

Reposeur, T.

1989-01-01

The proton-proton inelastic interaction, giving a neutral single pion, is studied. The reaction with two protons and one pi-zero in the final state for incident kinetic energies ranging from 480-560 MeV in 20 MeV steps is studied. It is necessary to develop a neutral pion spectrometer to detect in coincidence the two gammas of the decaying pi-zero. The detector has a good selectivity for neutral pion detection, and quantitative measurements require an accurate simulation of its response. The experiment shows that it is possible to measure the non resonant partial cross section. The relative accuracy on the total cross sections allows to search for a few percent effect. An isovector narrow dibaryonic resonance in that energy range, is suggested [fr

Polarized Proton Collisions at RHIC

CERN Document Server

Bai, Mei; Alekseev, Igor G; Alessi, James; Beebe-Wang, Joanne; Blaskiewicz, Michael; Bravar, Alessandro; Brennan, Joseph M; Bruno, Donald; Bunce, Gerry; Butler, John J; Cameron, Peter; Connolly, Roger; De Long, Joseph; Drees, Angelika; Fischer, Wolfram; Ganetis, George; Gardner, Chris J; Glenn, Joseph; Hayes, Thomas; Hseuh Hsiao Chaun; Huang, Haixin; Ingrassia, Peter; Iriso, Ubaldo; Laster, Jonathan S; Lee, Roger C; Luccio, Alfredo U; Luo, Yun; MacKay, William W; Makdisi, Yousef; Marr, Gregory J; Marusic, Al; McIntyre, Gary; Michnoff, Robert; Montag, Christoph; Morris, John; Nicoletti, Tony; Oddo, Peter; Oerter, Brian; Osamu, Jinnouchi; Pilat, Fulvia Caterina; Ptitsyn, Vadim; Roser, Thomas; Satogata, Todd; Smith, Kevin T; Svirida, Dima; Tepikian, Steven; Tomas, Rogelio; Trbojevic, Dejan; Tsoupas, Nicholaos; Tuozzolo, Joseph; Vetter, Kurt; Wilinski, Michelle; Zaltsman, Alex; Zelenski, Anatoli; Zeno, Keith; Zhang, S Y

2005-01-01

The Relativistic Heavy Ion Collider~(RHIC) provides not only collisions of ions but also collisions of polarized protons. In a circular accelerator, the polarization of polarized proton beam can be partially or fully lost when a spin depolarizing resonance is encountered. To preserve the beam polarization during acceleration, two full Siberian snakes were employed in RHIC to avoid depolarizing resonances. In 2003, polarized proton beams were accelerated to 100~GeV and collided in RHIC. Beams were brought into collisions with longitudinal polarization at the experiments STAR and PHENIX by using spin rotators. RHIC polarized proton run experience demonstrates that optimizing polarization transmission efficiency and improving luminosity performance are significant challenges. Currently, the luminosity lifetime in RHIC is limited by the beam-beam effect. The current state of RHIC polarized proton program, including its dedicated physics run in 2005 and efforts to optimize luminosity production in beam-beam limite...

Proton conduction in biopolymer exopolysaccharide succinoglycan

Energy Technology Data Exchange (ETDEWEB)

Kweon, Jin Jung [Department of Physics, Korea University, Seoul 136-713 (Korea, Republic of); National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida 32310 (United States); Lee, Kyu Won; Kim, Hyojung; Lee, Cheol Eui, E-mail: rscel@korea.ac.kr [Department of Physics, Korea University, Seoul 136-713 (Korea, Republic of); Jung, Seunho [Department of Bioscience and Biotechnology and UBITA, Konkuk University, Seoul 143-701 (Korea, Republic of); Kwon, Chanho [Naraebio Research Laboratories, 177 Dangha-ri, Bongdam-eup, Hawseong-si 445-892 (Korea, Republic of)

2014-07-07

Protonic currents play a vital role in electrical signalling in living systems. It has been suggested that succinoglycan plays a specific role in alfalfa root nodule development, presumably acting as the signaling molecules. In this regard, charge transport and proton dynamics in the biopolymer exopolysaccharide succinoglycan have been studied by means of electrical measurements and nuclear magnetic resonance (NMR) spectroscopy. In particular, a dielectric dispersion in the system has revealed that the electrical conduction is protonic rather electronic. Besides, our laboratory- and rotating-frame {sup 1}H NMR measurements have elucidated the nature of the protonic conduction, activation of the protonic motion being associated with a glass transition.

Recent Shuttle Post Flight MMOD Inspection Highlights

Science.gov (United States)

Hyed, James L.; Christiansen, Eric L.; Lear, Dana M.; Herrin, Jason S.

2009-01-01

Post flight inspections on the Space Shuttle Atlantis conducted after the STS-11.5 mission revealed a 0.11 inch (2.8 mm) hole in the outer face sheet of the starboard payload bay door radiator panel #4. The payload bay door radiators in this region are 0.5 inch (12.7 mm) thick aluminum honeycomb with 0.011 in (0.279 mm) thick aluminum face sheets topped with 0.005 in (0.127 mm) silver-Teflon tape. Inner face sheet damage included a 0.267 in (6.78 mm) long through crack with measureable deformation in the area of 0.2 in (5.1 mm). There was also a 0.031 in (0.787 nun) diameter hole in the rear face sheet. A large approximately l in (25 mm) diameter region of honeycomb was also destroyed. Since the radiators are located on the inside of the shuttle payload bay doors which are closed during ascent and reentry, the damage could only have occurred during the on-orbit portion of the mission. During the August 2007 STS-118 mission to the International Space Station, a micro-meteoroid or orbital debris (MMOD) particle impacted and completely penetrated one of shuttle Endeavour's radiator panels and the underlying thermal control system (TCS) blanket, leaving deposits on (but no damage to) the payload bay door. While it is not unusual for shuttle orbiters to be impacted by small MMOD particles, the damage from this impact is larger than any previously seen on the shuttle radiator panels. One of the largest impacts ever observed on a crew module window occurred during the November 2008 STS-126 mission to the International Space Station. Damage to the window was documented by the crew on orbit. Post flight inspection revealed a 0.4 in (10.8 mm) crater in the window pane, with a depth of 0.03 in (0.76 mm). The window pane was replaced due to the damage caused by this impact. Analysis performed on residue contained in dental mold impressions taken of the site indicated that a meteoroid particle produced this large damage site. The post flight inspection after the subsequent

Heme biomolecule as redox mediator and oxygen shuttle for efficient charging of lithium-oxygen batteries

Science.gov (United States)

Ryu, Won-Hee; Gittleson, Forrest S.; Thomsen, Julianne M.; Li, Jinyang; Schwab, Mark J.; Brudvig, Gary W.; Taylor, André D.

2016-01-01

One of the greatest challenges with lithium-oxygen batteries involves identifying catalysts that facilitate the growth and evolution of cathode species on an oxygen electrode. Heterogeneous solid catalysts cannot adequately address the problematic overpotentials when the surfaces become passivated. However, there exists a class of biomolecules which have been designed by nature to guide complex solution-based oxygen chemistries. Here, we show that the heme molecule, a common porphyrin cofactor in blood, can function as a soluble redox catalyst and oxygen shuttle for efficient oxygen evolution in non-aqueous Li-O2 batteries. The heme's oxygen binding capability facilitates battery recharge by accepting and releasing dissociated oxygen species while benefiting charge transfer with the cathode. We reveal the chemical change of heme redox molecules where synergy exists with the electrolyte species. This study brings focus to the rational design of solution-based catalysts and suggests a sustainable cross-link between biomolecules and advanced energy storage. PMID:27759005

Polarized proton colliders

International Nuclear Information System (INIS)

Roser, T.

1995-01-01

High energy polarized beam collisions will open up the unique physics opportunities of studying spin effects in hard processes. This will allow the study of the spin structure of the proton and also the verification of the many well documented expectations of spin effects in perturbative QCD and parity violation in W and Z production. Proposals for polarized proton acceleration for several high energy colliders have been developed. A partial Siberian Snake in the AGS has recently been successfully tested and full Siberian Snakes, spin rotators, and polarimeters for RHIC are being developed to make the acceleration of polarized beams to 250 GeV possible. This allows for the unique possibility of colliding two 250 GeV polarized proton beams at luminosities of up to 2 x 10 32 cm -2 s -1

Study on proton spin flip in scattering by Ti and Fe nuclei

International Nuclear Information System (INIS)

Korbetskij, E.V.; Prokopenko, V.S.; Sklyarenko, V.D.; Chernievskij, V.K.; Shustov, A.V.

1981-01-01

Spin-orbital effects and mechanisms of inelastic scattering of protons with energy of 6.9 MeV by sup(14, 48)Ti and sup(54, 56, 58)Fe are studied by the analysis of experimental results within the framework of the method of coupled channels. Simultaneously angular dependences of cross sections of elastic and inelastic (two first 2 + levels) scatterings and a probability of spin flip of proton at inelastic scattering are analysed. Experimental data were used for analysis, obtained in the given work, as well as the data published earlier. Targets are used in experiment which are in the form of self-sustaining fine (1-2 mg cm -2 ) films, enriched with corresponding isotope. Cross section determination error is 8% in the average. Obtained angular dependences of spin flip probability for sup(54, 56)Fe at Esub(p)=6.9 MeV are very similar in form and close in value to analogous at Esub(p)= 6 MeV, and differ greatly for 56 Fe at Esub(p)=5.88 MeV. Angular distributions of spin flip probabilities of protons from sup(54, 56)Fe (ppsub(1)) reaction at energies of 10, 11 and 12 MeV show the sufficient energy dependence of their shape and value. Experimental data are described satisfactorily witohin the framework of the cupled channel method namely - differential cross sections of elastic and inelastic scattering and angular dependences of the probability of spin flip at the interaction of protons with 6.9 MeV energy with sup(46, 48)Ti and sup(54, 56, 58)Fe nuclei. Difficulties, appearing in the description of cross sections of elastic scattering in case of sup(46, 48)Ti and of inelastic one for 56 Fe show that indirect processes are of importance in the present energy range and they should be taken into consideration [ru

Embedding of Hollow Polymer Microspheres with Hydrophilic Shell in Nafion Matrix as Proton and Water Micro-Reservoir

Directory of Open Access Journals (Sweden)

Zhaolin Liu

2012-08-01

Full Text Available Assimilating hydrophilic hollow polymer spheres (HPS into Nafion matrix by a loading of 0.5 wt % led to a restructured hydrophilic channel, composed of the pendant sulfonic acid groups (–SO₃H and the imbedded hydrophilic hollow spheres. The tiny hydrophilic hollow chamber was critical to retaining moisture and facilitating proton transfer in the composite membranes. To obtain such a tiny cavity structure, the synthesis included selective generation of a hydrophilic polymer shell on silica microsphere template and the subsequent removal of the template by etching. The hydrophilic HPS (100–200 nm possessed two different spherical shells, the styrenic network with pendant sulfonic acid groups and with methacrylic acid groups, respectively. By behaving as microreservoirs of water, the hydrophilic HPS promoted the Grotthus mechanism and, hence, enhanced proton transport efficiency through the inter-sphere path. In addition, the HPS with the –SO₃H borne shell played a more effective role than those with the –CO₂H borne shell in augmenting proton transport, in particular under low humidity or at medium temperatures. Single H₂-PEMFC test at 70 °C using dry H₂/O₂ further verified the impactful role of hydrophilic HPS in sustaining higher proton flux as compared to pristine Nafion membrane.

ATLAS Forward Proton Detector

CERN Document Server

Grieco, Chiara; The ATLAS collaboration

2018-01-01

The aim of the ATLAS Forward Proton (AFP) detector system is the measurement of protons scattered diffractively or electromagnetically at very small angles. The full two-arm setup was installed during the 2016/2017 EYETS. This allows measurements of processes with two forward protons: central diffraction, exclusive production, and two-photon processes. In 2017, AFP participated in the ATLAS high-luminosity data taking on the day-by-day basis. In addition, several special runs with reduced luminosity were taken. The poster will present the AFP detectors and the lessons learned from the last year operation and some performance from 2016 and 2017.

Microscopic study of proton emission from heavy nuclei

International Nuclear Information System (INIS)

Sahu, B.B.; Patra, S.K.; Agarwalla, S.K.

2011-01-01

In recent years many theoretical calculations have been employed to explain the observed lifetimes of proton radioactivity and alpha decay processes in the region of proton rich nuclei. These data are very promising for the analysis of possible irregularities in the structure of these proton-rich nuclei. They are also of great interest in rapid proton capture processes. Some new results for proton radioactivity in this region of proton-rich nuclei have indicated that the proton emission mode is rather competitive with the alpha decay one. In the energy domain of radioactivity, proton can be considered as a point charge having highest probability of being present in the parent nucleus

LHC Report: Ions cross protons

CERN Multimedia

Reyes Alemany Fernandez for the LHC team

2013-01-01

The LHC starts the New Year facing a new challenge: proton-lead collisions in the last month before the shutdown in mid-February.    The first stable beams were achieved on 20 January with 13 individual bunches per beam. In the next fill, the first bunch-trains were injected and stable beams were achieved with 96 proton on 120 ion bunches.  This fill was very important because we were able to study the so-called moving long-range beam-beam encounters. Long-range encounters, which are also seen in proton-proton runs, occur when the bunches in the two beams “see” each other as they travel in the same vacuum chamber at either side of the experiments.  The situation becomes more complicated with proton-lead ions because the two species have different revolution times (until the frequencies are locked at top energy- see “Cogging exercises”) and thus these encounters move. We found that this effect does not cause significant beam losses...

Proton beam monitor chamber calibration

International Nuclear Information System (INIS)

Gomà, C; Meer, D; Safai, S; Lorentini, S

2014-01-01

The first goal of this paper is to clarify the reference conditions for the reference dosimetry of clinical proton beams. A clear distinction is made between proton beam delivery systems which should be calibrated with a spread-out Bragg peak field and those that should be calibrated with a (pseudo-)monoenergetic proton beam. For the latter, this paper also compares two independent dosimetry techniques to calibrate the beam monitor chambers: absolute dosimetry (of the number of protons exiting the nozzle) with a Faraday cup and reference dosimetry (i.e. determination of the absorbed dose to water under IAEA TRS-398 reference conditions) with an ionization chamber. To compare the two techniques, Monte Carlo simulations were performed to convert dose-to-water to proton fluence. A good agreement was found between the Faraday cup technique and the reference dosimetry with a plane-parallel ionization chamber. The differences—of the order of 3%—were found to be within the uncertainty of the comparison. For cylindrical ionization chambers, however, the agreement was only possible when positioning the effective point of measurement of the chamber at the reference measurement depth—i.e. not complying with IAEA TRS-398 recommendations. In conclusion, for cylindrical ionization chambers, IAEA TRS-398 reference conditions for monoenergetic proton beams led to a systematic error in the determination of the absorbed dose to water, especially relevant for low-energy proton beams. To overcome this problem, the effective point of measurement of cylindrical ionization chambers should be taken into account when positioning the reference point of the chamber. Within the current IAEA TRS-398 recommendations, it seems advisable to use plane-parallel ionization chambers—rather than cylindrical chambers—for the reference dosimetry of pseudo-monoenergetic proton beams. (paper)

Proton drip-line studies at HRIBF

International Nuclear Information System (INIS)

Rykaczewski, K.P.; Batchelder, J.C.; Bingham, C.R.; Bryan, R.E.; Davinson, T.; Woods, P.J.; Ginter, T.N.; Hamilton, J. H.; Gross, C.J.; Grzywacz, R.; Janas, Z.; Karny, M.; MacDonald, B.D.; McConnell, J.W.; Toth, K.S.; Piechaczek, A.; Zganjar, E.F.; Szerypo, J.; Walters, W. B.

2000-01-01

Proton radioactivity studies performed at the Holifield Radioactive Ion Beam Facility (HFBR) within the last few years are reviewed. The discovery of five new proton radioactivities 140 Ho, 141m Ho, 145 Tm, 150m Lu and 151m Lu is presented together with a recent observation of fine structure in proton emission from 146gs,m Tm. These proton emitters were produced by means of fusion-evaporation reactions and studied with the HFBR Recoil Mass Separator and detection system based on a Double-sided Silicon Strip Detector. For 113 Cs and 151 Lu, the studies of level structure were extended beyond the proton-emitting states via the measurements with a clover array Clarion using Recoil Decay Tagging

Shuttling of G protein subunits between the plasma membrane and intracellular membranes.

Science.gov (United States)

Chisari, Mariangela; Saini, Deepak Kumar; Kalyanaraman, Vani; Gautam, Narasimhan

2007-08-17

Heterotrimeric G proteins (alphabetagamma) mediate the majority of signaling pathways in mammalian cells. It is long held that G protein function is localized to the plasma membrane. Here we examined the spatiotemporal dynamics of G protein localization using fluorescence recovery after photobleaching, fluorescence loss in photobleaching, and a photoswitchable fluorescent protein, Dronpa. Unexpectedly, G protein subunits shuttle rapidly (t1/2 plasma membrane and intracellular membranes. We show that consistent with such shuttling, G proteins constitutively reside in endomembranes. Furthermore, we show that shuttling is inhibited by 2-bromopalmitate. Thus, contrary to present thought, G proteins do not reside permanently on the plasma membrane but are constantly testing the cytoplasmic surfaces of the plasma membrane and endomembranes to maintain G protein pools in intracellular membranes to establish direct communication between receptors and endomembranes.

High-energy proton irradiation of C57Bl6 mice under hindlimb unloading

Science.gov (United States)

Mendonca, Marc; Todd, Paul; Orschell, Christie; Chin-Sinex, Helen; Farr, Jonathan; Klein, Susan; Sokol, Paul

2012-07-01

Solar proton events (SPEs) pose substantial risk for crewmembers on deep space missions. It has been shown that low gravity and ionizing radiation both produce transient anemia and immunodeficiencies. We utilized the C57Bl/6 based hindlimb suspension model to investigate the consequences of hindlimb-unloading induced immune suppression on the sensitivity to whole body irradiation with modulated 208 MeV protons. Eight-week old C57Bl/6 female mice were conditioned by hindlimb-unloading. Serial CBC and hematocrit assays by HEMAVET were accumulated for the hindlimb-unloaded mice and parallel control animals subjected to identical conditions without unloading. One week of hindlimb-unloading resulted in a persistent, statistically significant 10% reduction in RBC count and a persistent, statistically significant 35% drop in lymphocyte count. This inhibition is consistent with published observations of low Earth orbit flown mice and with crewmember blood analyses. In our experiments the cell count suppression was sustained for the entire six-week period of observation and persisted for at least 7 days beyond the period of active hindlimb-unloading. C57Bl/6 mice were also irradiated with 208 MeV Spread Out Bragg Peak (SOBP) protons at the Midwest Proton Radiotherapy Institute at the Indiana University Cyclotron Facility. We found that at 8.5 Gy hindlimb-unloaded mice were significantly more radiation sensitive with 35 lethalities out of 51 mice versus 15 out of 45 control (non-suspended) mice within 30 days of receiving 8.5 Gy of SOBP protons (p =0.001). Both control and hindlimb-unloaded stocktickerCBC analyses of 8.5 Gy proton irradiated and control mice by HEMAVET demonstrated severe reductions in WBC counts (Lymphocytes and PMNs) by day 2 post-irradiation, followed a week to ten days later by reductions in platelets, and then reductions in RBCs about 2 weeks post-irradiation. Recovery of all blood components commenced by three weeks post-irradiation. CBC analyses of 8

Proton radioactivity lifetimes using Skyrme interactions

International Nuclear Information System (INIS)

Routray, T.R.; Tripathy, S.K.; Mishra, Abhishek; Basu, D.N.

2011-01-01

The phenomena of proton radioactivity is recent and has been possible with the advent of the radioactive ion beams facilities. The neutron deficient nuclei lying above the proton drip line has positive Q values for protons and are spontaneous proton emitters. This limits the possibilities of the creation of ever more exotic nuclei in the proton rich side of the β stability valley. Limited number of works have been done in calculating the half lives of proton emitting nuclei using different models. But calculation of lifetimes of the proton emitting nuclei using Skyrme interaction has not yet been reported. More than 110 Skyrme sets are available, constructed for different purposes, all having the common feature of giving finite nuclei ground state properties and saturation conditions in nuclear matter. Skyrme sets constructed in the late 90's, particularly the construction of SLy sets and others Skyrme sets developed thereafter, have additional care in constraining the parameters for applications to nuclear matter under extreme conditions. Stone et al. have analyzed the Skyrme sets on the basis of available constraints and have sorted out finally 27 Skyrmes sets which can be admitted for calculation of isospin rich dense nuclear matter. The objective of the work is to examine the predictions of the Skyrme sets on the half lives of the proton emitters

Measurement of pion, kaon and proton production in proton-proton collisions at $\\sqrt{s}$ = 7 TeV

CERN Document Server

Adam, Jaroslav; Aggarwal, Madan Mohan; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Neelima; Ahammed, Zubayer; Ahmed, Ijaz; Ahn, Sang Un; Aimo, Ilaria; Aiola, Salvatore; Ajaz, Muhammad; Akindinov, Alexander; Alam, Sk Noor; Aleksandrov, Dmitry; Alessandro, Bruno; Alexandre, Didier; Alfaro Molina, Jose Ruben; Alici, Andrea; Alkin, Anton; Alme, Johan; Alt, Torsten; Altinpinar, Sedat; Altsybeev, Igor; Alves Garcia Prado, Caio; Andrei, Cristian; Andronic, Anton; Anguelov, Venelin; Anielski, Jonas; Anticic, Tome; Antinori, Federico; Antonioli, Pietro; Aphecetche, Laurent Bernard; Appelshaeuser, Harald; Arcelli, Silvia; Armesto Perez, Nestor; Arnaldi, Roberta; Aronsson, Tomas; Arsene, Ionut Cristian; Arslandok, Mesut; Augustinus, Andre; Averbeck, Ralf Peter; Azmi, Mohd Danish; Bach, Matthias Jakob; Badala, Angela; Baek, Yong Wook; Bagnasco, Stefano; Bailhache, Raphaelle Marie; Bala, Renu; Baldisseri, Alberto; Ball, Markus; Baltasar Dos Santos Pedrosa, Fernando; Baral, Rama Chandra; Barbano, Anastasia Maria; Barbera, Roberto; Barile, Francesco; Barnafoldi, Gergely Gabor; Barnby, Lee Stuart; Ramillien Barret, Valerie; Bartalini, Paolo; Bartke, Jerzy Gustaw; Bartsch, Esther; Basile, Maurizio; Bastid, Nicole; Basu, Sumit; Bathen, Bastian; Batigne, Guillaume; Batista Camejo, Arianna; Batyunya, Boris; Batzing, Paul Christoph; Bearden, Ian Gardner; Beck, Hans; Bedda, Cristina; Behera, Nirbhay Kumar; Belikov, Iouri; Bellini, Francesca; Bello Martinez, Hector; Bellwied, Rene; Belmont Iii, Ronald John; Belmont Moreno, Ernesto; Belyaev, Vladimir; Bencedi, Gyula; Beole, Stefania; Berceanu, Ionela; Bercuci, Alexandru; Berdnikov, Yaroslav; Berenyi, Daniel; Bertens, Redmer Alexander; Berzano, Dario; Betev, Latchezar; Bhasin, Anju; Bhat, Inayat Rasool; Bhati, Ashok Kumar; Bhattacharjee, Buddhadeb; Bhom, Jihyun; Bianchi, Livio; Bianchi, Nicola; Bianchin, Chiara; Bielcik, Jaroslav; Bielcikova, Jana; Bilandzic, Ante; Biswas, Saikat; Bjelogrlic, Sandro; Blanco, Fernando; Blau, Dmitry; Blume, Christoph; Bock, Friederike; Bogdanov, Alexey; Boggild, Hans; Boldizsar, Laszlo; Bombara, Marek; Book, Julian Heinz; Borel, Herve; Borissov, Alexander; Borri, Marcello; Bossu, Francesco; Botje, Michiel; Botta, Elena; Boettger, Stefan; Braun-Munzinger, Peter; Bregant, Marco; Breitner, Timo Gunther; Broker, Theo Alexander; Browning, Tyler Allen; Broz, Michal; Brucken, Erik Jens; Bruna, Elena; Bruno, Giuseppe Eugenio; Budnikov, Dmitry; Buesching, Henner; Bufalino, Stefania; Buncic, Predrag; Busch, Oliver; Buthelezi, Edith Zinhle; Buxton, Jesse Thomas; Caffarri, Davide; Cai, Xu; Caines, Helen Louise; Calero Diaz, Liliet; Caliva, Alberto; Calvo Villar, Ernesto; Camerini, Paolo; Carena, Francesco; Carena, Wisla; Castillo Castellanos, Javier Ernesto; Castro, Andrew John; Casula, Ester Anna Rita; Cavicchioli, Costanza; Ceballos Sanchez, Cesar; Cepila, Jan; Cerello, Piergiorgio; Chang, Beomsu; Chapeland, Sylvain; Chartier, Marielle; Charvet, Jean-Luc Fernand; Chattopadhyay, Subhasis; Chattopadhyay, Sukalyan; Chelnokov, Volodymyr; Cherney, Michael Gerard; Cheshkov, Cvetan Valeriev; Cheynis, Brigitte; Chibante Barroso, Vasco Miguel; Dobrigkeit Chinellato, David; Chochula, Peter; Choi, Kyungeon; Chojnacki, Marek; Choudhury, Subikash; Christakoglou, Panagiotis; Christensen, Christian Holm; Christiansen, Peter; Chujo, Tatsuya; Chung, Suh-Urk; Cicalo, Corrado; Cifarelli, Luisa; Cindolo, Federico; Cleymans, Jean Willy Andre; Colamaria, Fabio Filippo; Colella, Domenico; Collu, Alberto; Colocci, Manuel; Conesa Balbastre, Gustavo; Conesa Del Valle, Zaida; Connors, Megan Elizabeth; Contreras Nuno, Jesus Guillermo; Cormier, Thomas Michael; Corrales Morales, Yasser; Cortes Maldonado, Ismael; Cortese, Pietro; Cosentino, Mauro Rogerio; Costa, Filippo; Crochet, Philippe; Cruz Albino, Rigoberto; Cuautle Flores, Eleazar; Cunqueiro Mendez, Leticia; Dahms, Torsten; Dainese, Andrea; Danu, Andrea; Das, Debasish; Das, Indranil; Das, Supriya; Dash, Ajay Kumar; Dash, Sadhana; De, Sudipan; De Caro, Annalisa; De Cataldo, Giacinto; De Cuveland, Jan; De Falco, Alessandro; De Gruttola, Daniele; De Marco, Nora; De Pasquale, Salvatore; Deisting, Alexander; Deloff, Andrzej; Denes, Ervin Sandor; D'Erasmo, Ginevra; Di Bari, Domenico; Di Mauro, Antonio; Di Nezza, Pasquale; Diaz Corchero, Miguel Angel; Dietel, Thomas; Dillenseger, Pascal; Divia, Roberto; Djuvsland, Oeystein; Dobrin, Alexandru Florin; Dobrowolski, Tadeusz Antoni; Domenicis Gimenez, Diogenes; Donigus, Benjamin; Dordic, Olja; Dubey, Anand Kumar; Dubla, Andrea; Ducroux, Laurent; Dupieux, Pascal; Ehlers Iii, Raymond James; Elia, Domenico; Engel, Heiko; Erazmus, Barbara Ewa; Erhardt, Filip; Eschweiler, Dominic; Espagnon, Bruno; Estienne, Magali Danielle; Esumi, Shinichi; Eum, Jongsik; Evans, David; Evdokimov, Sergey; Eyyubova, Gyulnara; Fabbietti, Laura; Fabris, Daniela; Faivre, Julien; Fantoni, Alessandra; Fasel, Markus; Feldkamp, Linus; Felea, Daniel; Feliciello, Alessandro; Feofilov, Grigorii; Ferencei, Jozef; Fernandez Tellez, Arturo; Gonzalez Ferreiro, Elena; Ferretti, Alessandro; Festanti, Andrea; Figiel, Jan; Araujo Silva Figueredo, Marcel; Filchagin, Sergey; Finogeev, Dmitry; Fionda, Fiorella; Fiore, Enrichetta Maria; Floris, Michele; Foertsch, Siegfried Valentin; Foka, Panagiota; Fokin, Sergey; Fragiacomo, Enrico; Francescon, Andrea; Frankenfeld, Ulrich Michael; Fuchs, Ulrich; Furget, Christophe; Furs, Artur; Fusco Girard, Mario; Gaardhoeje, Jens Joergen; Gagliardi, Martino; Gago Medina, Alberto Martin; Gallio, Mauro; Gangadharan, Dhevan Raja; Ganoti, Paraskevi; Gao, Chaosong; Garabatos Cuadrado, Jose; Garcia-Solis, Edmundo Javier; Gargiulo, Corrado; Gasik, Piotr Jan; Germain, Marie; Gheata, Andrei George; Gheata, Mihaela; Ghosh, Premomoy; Ghosh, Sanjay Kumar; Gianotti, Paola; Giubellino, Paolo; Giubilato, Piero; Gladysz-Dziadus, Ewa; Glassel, Peter; Gomez Ramirez, Andres; Gonzalez Zamora, Pedro; Gorbunov, Sergey; Gorlich, Lidia Maria; Gotovac, Sven; Grabski, Varlen; Graczykowski, Lukasz Kamil; Grelli, Alessandro; Grigoras, Alina Gabriela; Grigoras, Costin; Grigoryev, Vladislav; Grigoryan, Ara; Grigoryan, Smbat; Grynyov, Borys; Grion, Nevio; Grosse-Oetringhaus, Jan Fiete; Grossiord, Jean-Yves; Grosso, Raffaele; Guber, Fedor; Guernane, Rachid; Guerzoni, Barbara; Gulbrandsen, Kristjan Herlache; Gulkanyan, Hrant; Gunji, Taku; Gupta, Anik; Gupta, Ramni; Haake, Rudiger; Haaland, Oystein Senneset; Hadjidakis, Cynthia Marie; Haiduc, Maria; Hamagaki, Hideki; Hamar, Gergoe; Hanratty, Luke David; Hansen, Alexander; Harris, John William; Hartmann, Helvi; Harton, Austin Vincent; Hatzifotiadou, Despina; Hayashi, Shinichi; Heckel, Stefan Thomas; Heide, Markus Ansgar; Helstrup, Haavard; Herghelegiu, Andrei Ionut; Herrera Corral, Gerardo Antonio; Hess, Benjamin Andreas; Hetland, Kristin Fanebust; Hilden, Timo Eero; Hillemanns, Hartmut; Hippolyte, Boris; Hristov, Peter Zahariev; Huang, Meidana; Humanic, Thomas; Hussain, Nur; Hussain, Tahir; Hutter, Dirk; Hwang, Dae Sung; Ilkaev, Radiy; Ilkiv, Iryna; Inaba, Motoi; Ionita, Costin; Ippolitov, Mikhail; Irfan, Muhammad; Ivanov, Marian; Ivanov, Vladimir; Izucheev, Vladimir; Jacobs, Peter Martin; Jahnke, Cristiane; Jang, Haeng Jin; Janik, Malgorzata Anna; Pahula Hewage, Sandun; Jena, Chitrasen; Jena, Satyajit; Jimenez Bustamante, Raul Tonatiuh; Jones, Peter Graham; Jung, Hyungtaik; Jusko, Anton; Kadyshevskiy, Vladimir; Kalinak, Peter; Kalweit, Alexander Philipp; Kamin, Jason Adrian; Kang, Ju Hwan; Kaplin, Vladimir; Kar, Somnath; Karasu Uysal, Ayben; Karavichev, Oleg; Karavicheva, Tatiana; Karpechev, Evgeny; Kebschull, Udo Wolfgang; Keidel, Ralf; Keijdener, Darius Laurens; Keil, Markus; Khan, Kamal; Khan, Mohammed Mohisin; Khan, Palash; Khan, Shuaib Ahmad; Khanzadeev, Alexei; Kharlov, Yury; Kileng, Bjarte; Kim, Beomkyu; Kim, Do Won; Kim, Dong Jo; Kim, Hyeonjoong; Kim, Jinsook; Kim, Mimae; Kim, Minwoo; Kim, Se Yong; Kim, Taesoo; Kirsch, Stefan; Kisel, Ivan; Kiselev, Sergey; Kisiel, Adam Ryszard; Kiss, Gabor; Klay, Jennifer Lynn; Klein, Carsten; Klein, Jochen; Klein-Boesing, Christian; Kluge, Alexander; Knichel, Michael Linus; Knospe, Anders Garritt; Kobayashi, Taiyo; Kobdaj, Chinorat; Kofarago, Monika; Kohler, Markus Konrad; Kollegger, Thorsten; Kolozhvari, Anatoly; Kondratev, Valerii; Kondratyeva, Natalia; Kondratyuk, Evgeny; Konevskikh, Artem; Kouzinopoulos, Charalampos; Kovalenko, Oleksandr; Kovalenko, Vladimir; Kowalski, Marek; Kox, Serge; Koyithatta Meethaleveedu, Greeshma; Kral, Jiri; Kralik, Ivan; Kravcakova, Adela; Krelina, Michal; Kretz, Matthias; Krivda, Marian; Krizek, Filip; Kryshen, Evgeny; Krzewicki, Mikolaj; Kubera, Andrew Michael; Kucera, Vit; Kucheryaev, Yury; Kugathasan, Thanushan; Kuhn, Christian Claude; Kuijer, Paulus Gerardus; Kulakov, Igor; Kumar, Jitendra; Kurashvili, Podist; Kurepin, Alexander; Kurepin, Alexey; Kuryakin, Alexey; Kushpil, Svetlana; Kweon, Min Jung; Kwon, Youngil; La Pointe, Sarah Louise; La Rocca, Paola; Lagana Fernandes, Caio; Lakomov, Igor; Langoy, Rune; Lara Martinez, Camilo Ernesto; Lardeux, Antoine Xavier; Lattuca, Alessandra; Laudi, Elisa; Lea, Ramona; Leardini, Lucia; Lee, Graham Richard; Lee, Seongjoo; Legrand, Iosif; Lehnert, Joerg Walter; Lemmon, Roy Crawford; Lenti, Vito; Leogrande, Emilia; Leon Monzon, Ildefonso; Leoncino, Marco; Levai, Peter; Li, Shuang; Li, Xiaomei; Lien, Jorgen Andre; Lietava, Roman; Lindal, Svein; Lindenstruth, Volker; Lippmann, Christian; Lisa, Michael Annan; Ljunggren, Hans Martin; Lodato, Davide Francesco; Lonne, Per-Ivar; Loggins, Vera Renee; Loginov, Vitaly; Loizides, Constantinos; Lokesh, Kumar; Lopez, Xavier Bernard; Lopez Torres, Ernesto; Lowe, Andrew John; Lu, Xianguo; Luettig, Philipp Johannes; Lunardon, Marcello; Luparello, Grazia; Maevskaya, Alla; Mager, Magnus; Mahajan, Sanjay; Mahmood, Sohail Musa; Maire, Antonin; Majka, Richard Daniel; Malaev, Mikhail; Maldonado Cervantes, Ivonne Alicia; Malinina, Liudmila; Mal'Kevich, Dmitry; Malzacher, Peter; Mamonov, Alexander; Manceau, Loic Henri Antoine; Manko, Vladislav; Manso, Franck; Manzari, Vito; Marchisone, Massimiliano; Mares, Jiri; Margagliotti, Giacomo Vito; Margotti, Anselmo; Margutti, Jacopo; Marin, Ana Maria; Markert, Christina; Marquard, Marco; Martin, Nicole Alice; Martin Blanco, Javier; Martinengo, Paolo; Martinez Hernandez, Mario Ivan; Martinez-Garcia, Gines; Martinez Pedreira, Miguel; Martynov, Yevgen; Mas, Alexis Jean-Michel; Masciocchi, Silvia; Masera, Massimo; Masoni, Alberto; Massacrier, Laure Marie; Mastroserio, Annalisa; Masui, Hiroshi; Matyja, Adam Tomasz; Mayer, Christoph; Mazer, Joel Anthony; Mazzoni, Alessandra Maria; Mcdonald, Daniel; Meddi, Franco; Menchaca-Rocha, Arturo Alejandro; Meninno, Elisa; Mercado-Perez, Jorge; Meres, Michal; Miake, Yasuo; Mieskolainen, Matti Mikael; Mikhaylov, Konstantin; Milano, Leonardo; Milosevic, Jovan; Minervini, Lazzaro Manlio; Mischke, Andre; Mishra, Aditya Nath; Miskowiec, Dariusz Czeslaw; Mitra, Jubin; Mitu, Ciprian Mihai; Mohammadi, Naghmeh; Mohanty, Bedangadas; Molnar, Levente; Montano Zetina, Luis Manuel; Montes Prado, Esther; Morando, Maurizio; Moreira De Godoy, Denise Aparecida; Moretto, Sandra; Morreale, Astrid; Morsch, Andreas; Muccifora, Valeria; Mudnic, Eugen; Muhlheim, Daniel Michael; Muhuri, Sanjib; Mukherjee, Maitreyee; Muller, Hans; Mulligan, James Declan; Gameiro Munhoz, Marcelo; Murray, Sean; Musa, Luciano; Musinsky, Jan; Nandi, Basanta Kumar; Nania, Rosario; Nappi, Eugenio; Naru, Muhammad Umair; Nattrass, Christine; Nayak, Kishora; Nayak, Tapan Kumar; Nazarenko, Sergey; Nedosekin, Alexander; Nellen, Lukas; Ng, Fabian; Nicassio, Maria; Niculescu, Mihai; Niedziela, Jeremi; Nielsen, Borge Svane; Nikolaev, Sergey; Nikulin, Sergey; Nikulin, Vladimir; Noferini, Francesco; Nomokonov, Petr; Nooren, Gerardus; Norman, Jaime; Nyanin, Alexander; Nystrand, Joakim Ingemar; Oeschler, Helmut Oskar; Oh, Saehanseul; Oh, Sun Kun; Ohlson, Alice Elisabeth; Okatan, Ali; Okubo, Tsubasa; Olah, Laszlo; Oleniacz, Janusz; Oliveira Da Silva, Antonio Carlos; Oliver, Michael Henry; Onderwaater, Jacobus; Oppedisano, Chiara; Ortiz Velasquez, Antonio; Oskarsson, Anders Nils Erik; Otwinowski, Jacek Tomasz; Oyama, Ken; Ozdemir, Mahmut; Pachmayer, Yvonne Chiara; Pagano, Paola; Paic, Guy; Pajares Vales, Carlos; Pal, Susanta Kumar; Pan, Jinjin; Pant, Divyash; Papikyan, Vardanush; Pappalardo, Giuseppe; Pareek, Pooja; Park, Woojin; Parmar, Sonia; Passfeld, Annika; Paticchio, Vincenzo; Paul, Biswarup; Pawlak, Tomasz Jan; Peitzmann, Thomas; Pereira Da Costa, Hugo Denis Antonio; Pereira De Oliveira Filho, Elienos; Peresunko, Dmitry Yurevich; Perez Lara, Carlos Eugenio; Peskov, Vladimir; Pestov, Yury; Petracek, Vojtech; Petrov, Viacheslav; Petrovici, Mihai; Petta, Catia; Piano, Stefano; Pikna, Miroslav; Pillot, Philippe; Pinazza, Ombretta; Pinsky, Lawrence; Piyarathna, Danthasinghe; Ploskon, Mateusz Andrzej; Planinic, Mirko; Pluta, Jan Marian; Pochybova, Sona; Podesta Lerma, Pedro Luis Manuel; Poghosyan, Martin; Polishchuk, Boris; Poljak, Nikola; Poonsawat, Wanchaloem; Pop, Amalia; Porteboeuf, Sarah Julie; Porter, R Jefferson; Pospisil, Jan; Prasad, Sidharth Kumar; Preghenella, Roberto; Prino, Francesco; Pruneau, Claude Andre; Pshenichnov, Igor; Puccio, Maximiliano; Puddu, Giovanna; Pujahari, Prabhat Ranjan; Punin, Valery; Putschke, Jorn Henning; Qvigstad, Henrik; Rachevski, Alexandre; Raha, Sibaji; Rajput, Sonia; Rak, Jan; Rakotozafindrabe, Andry Malala; Ramello, Luciano; Raniwala, Rashmi; Raniwala, Sudhir; Rasanen, Sami Sakari; Rascanu, Bogdan Theodor; Rathee, Deepika; Razazi, Vahedeh; Read, Kenneth Francis; Real, Jean-Sebastien; Redlich, Krzysztof; Reed, Rosi Jan; Rehman, Attiq Ur; Reichelt, Patrick Simon; Reicher, Martijn; Reidt, Felix; Ren, Xiaowen; Renfordt, Rainer Arno Ernst; Reolon, Anna Rita; Reshetin, Andrey; Rettig, Felix Vincenz; Revol, Jean-Pierre; Reygers, Klaus Johannes; Riabov, Viktor; Ricci, Renato Angelo; Richert, Tuva Ora Herenui; Richter, Matthias Rudolph; Riedler, Petra; Riegler, Werner; Riggi, Francesco; Ristea, Catalin-Lucian; Rivetti, Angelo; Rocco, Elena; Rodriguez Cahuantzi, Mario; Rodriguez Manso, Alis; Roeed, Ketil; Rogochaya, Elena; Rohr, David Michael; Roehrich, Dieter; Romita, Rosa; Ronchetti, Federico; Ronflette, Lucile; Rosnet, Philippe; Rossi, Andrea; Roukoutakis, Filimon; Roy, Ankhi; Roy, Christelle Sophie; Roy, Pradip Kumar; Rubio Montero, Antonio Juan; Rui, Rinaldo; Russo, Riccardo; Ryabinkin, Evgeny; Ryabov, Yury; Rybicki, Andrzej; Sadovskiy, Sergey; Safarik, Karel; Sahlmuller, Baldo; Sahoo, Pragati; Sahoo, Raghunath; Sahoo, Sarita; Sahu, Pradip Kumar; Saini, Jogender; Sakai, Shingo; Saleh, Mohammad Ahmad; Salgado Lopez, Carlos Alberto; Salzwedel, Jai Samuel Nielsen; Sambyal, Sanjeev Singh; Samsonov, Vladimir; Sanchez Castro, Xitzel; Sandor, Ladislav; Sandoval, Andres; Sano, Masato; Santagati, Gianluca; Sarkar, Debojit; Scapparone, Eugenio; Scarlassara, Fernando; Scharenberg, Rolf Paul; Schiaua, Claudiu Cornel; Schicker, Rainer Martin; Schmidt, Christian Joachim; Schmidt, Hans Rudolf; Schuchmann, Simone; Schukraft, Jurgen; Schulc, Martin; Schuster, Tim Robin; Schutz, Yves Roland; Schwarz, Kilian Eberhard; Schweda, Kai Oliver; Scioli, Gilda; Scomparin, Enrico; Scott, Rebecca Michelle; Seeder, Karin Soraya; Seger, Janet Elizabeth; Sekiguchi, Yuko; Selyuzhenkov, Ilya; Senosi, Kgotlaesele; Seo, Jeewon; Serradilla Rodriguez, Eulogio; Sevcenco, Adrian; Shabanov, Arseniy; Shabetai, Alexandre; Shadura, Oksana; Shahoyan, Ruben; Shangaraev, Artem; Sharma, Ankita; Sharma, Natasha; Shigaki, Kenta; Shtejer Diaz, Katherin; Sibiryak, Yury; Siddhanta, Sabyasachi; Sielewicz, Krzysztof Marek; Siemiarczuk, Teodor; Silvermyr, David Olle Rickard; Silvestre, Catherine Micaela; Simatovic, Goran; Simonetti, Giuseppe; Singaraju, Rama Narayana; Singh, Ranbir; Singha, Subhash; Singhal, Vikas; Sinha, Bikash; Sarkar - Sinha, Tinku; Sitar, Branislav; Sitta, Mario; Skaali, Bernhard; Slupecki, Maciej; Smirnov, Nikolai; Snellings, Raimond; Snellman, Tomas Wilhelm; Soegaard, Carsten; Soltz, Ron Ariel; Song, Jihye; Song, Myunggeun; Song, Zixuan; Soramel, Francesca; Sorensen, Soren Pontoppidan; Spacek, Michal; Spiriti, Eleuterio; Sputowska, Iwona Anna; Spyropoulou-Stassinaki, Martha; Srivastava, Brijesh Kumar; Stachel, Johanna; Stan, Ionel; Stefanek, Grzegorz; Steinpreis, Matthew Donald; Stenlund, Evert Anders; Steyn, Gideon Francois; Stiller, Johannes Hendrik; Stocco, Diego; Strmen, Peter; Alarcon Do Passo Suaide, Alexandre; Sugitate, Toru; Suire, Christophe Pierre; Suleymanov, Mais Kazim Oglu; Sultanov, Rishat; Sumbera, Michal; Symons, Timothy; Szabo, Alexander; Szanto De Toledo, Alejandro; Szarka, Imrich; Szczepankiewicz, Adam; Szymanski, Maciej Pawel; Takahashi, Jun; Tanaka, Naoto; Tangaro, Marco-Antonio; Tapia Takaki, Daniel Jesus; Tarantola Peloni, Attilio; Tariq, Mohammad; Tarzila, Madalina-Gabriela; Tauro, Arturo; Tejeda Munoz, Guillermo; Telesca, Adriana; Terasaki, Kohei; Terrevoli, Cristina; Teyssier, Boris; Thaeder, Jochen Mathias; Thomas, Deepa; Tieulent, Raphael Noel; Timmins, Anthony Robert; Toia, Alberica; Trogolo, Stefano; Trubnikov, Victor; Trzaska, Wladyslaw Henryk; Tsuji, Tomoya; Tumkin, Alexandr; Turrisi, Rosario; Tveter, Trine Spedstad; Ullaland, Kjetil; Uras, Antonio; Usai, Gianluca; Utrobicic, Antonija; Vajzer, Michal; Vala, Martin; Valencia Palomo, Lizardo; Vallero, Sara; Van Der Maarel, Jasper; Van Hoorne, Jacobus Willem; Van Leeuwen, Marco; Vanat, Tomas; Vande Vyvre, Pierre; Varga, Dezso; Diozcora Vargas Trevino, Aurora; Vargyas, Marton; Varma, Raghava; Vasileiou, Maria; Vasiliev, Andrey; Vauthier, Astrid; Vechernin, Vladimir; Veen, Annelies Marianne; Veldhoen, Misha; Velure, Arild; Venaruzzo, Massimo; Vercellin, Ermanno; Vergara Limon, Sergio; Vernet, Renaud; Verweij, Marta; Vickovic, Linda; Viesti, Giuseppe; Viinikainen, Jussi Samuli; Vilakazi, Zabulon; Villalobos Baillie, Orlando; Vinogradov, Alexander; Vinogradov, Leonid; Vinogradov, Yury; Virgili, Tiziano; Vislavicius, Vytautas; Viyogi, Yogendra; Vodopyanov, Alexander; Volkl, Martin Andreas; Voloshin, Kirill; Voloshin, Sergey; Volpe, Giacomo; Von Haller, Barthelemy; Vorobyev, Ivan; Vranic, Danilo; Vrlakova, Janka; Vulpescu, Bogdan; Vyushin, Alexey; Wagner, Boris; Wagner, Jan; Wang, Hongkai; Wang, Mengliang; Wang, Yifei; Watanabe, Daisuke; Weber, Michael; Weber, Steffen Georg; Wessels, Johannes Peter; Westerhoff, Uwe; Wiechula, Jens; Wikne, Jon; Wilde, Martin Rudolf; Wilk, Grzegorz Andrzej; Wilkinson, Jeremy John; Williams, Crispin; Windelband, Bernd Stefan; Winn, Michael Andreas; Yaldo, Chris G; Yamaguchi, Yorito; Yang, Hongyan; Yang, Ping; Yano, Satoshi; Yasnopolskiy, Stanislav; Yin, Zhongbao; Yokohama, Hiroki; Yoo, In-Kwon; Yurchenko, Volodymyr; Yushmanov, Igor; Zaborowska, Anna; Zaccolo, Valentina; Zaman, Ali; Zampolli, Chiara; Correia Zanoli, Henrique Jose; Zaporozhets, Sergey; Zarochentsev, Andrey; Zavada, Petr; Zavyalov, Nikolay; Zbroszczyk, Hanna Paulina; Zgura, Sorin Ion; Zhalov, Mikhail; Zhang, Haitao; Zhang, Xiaoming; Zhang, Yonghong; Zhao, Chengxin; Zhigareva, Natalia; Zhou, Daicui; Zhou, You; Zhou, Zhuo; Zhu, Hongsheng; Zhu, Jianhui; Zhu, Xiangrong; Zichichi, Antonino; Zimmermann, Alice; Zimmermann, Markus Bernhard; Zinovjev, Gennady; Zyzak, Maksym

2015-05-27

The measurement of primary $\\pi^{\\pm}$, K$^{\\pm}$, p and $\\overline{p}$ production at mid-rapidity ($|y| <$ 0.5) in proton-proton collisions at $\\sqrt{s} = 7$ TeV performed with ALICE (A Large Ion Collider Experiment) at the Large Hadron Collider (LHC) is reported. Particle identification is performed using the specific ionization energy loss and time-of-flight information, the ring-imaging Cherenkov technique and the kink-topology identification of weak decays of charged kaons. Transverse momentum spectra are measured from 0.1 up to 3 GeV/$c$ for pions, from 0.2 up to 6 GeV/$c$ for kaons and from 0.3 up to 6 GeV/$c$ for protons. The measured spectra and particle ratios are compared with QCD-inspired models, tuned to reproduce also the earlier measurements performed at the LHC. Furthermore, the integrated particle yields and ratios as well as the average transverse momenta are compared with results at lower collision energies.

Mission Operations Directorate - Success Legacy of the Space Shuttle Program (Overview of the Evolution and Success Stories from MOD During the Space Shuttle program)

Science.gov (United States)

Azbell, Jim A.

2011-01-01

In support of the Space Shuttle Program, as well as NASA's other human space flight programs, the Mission Operations Directorate (MOD) at the Johnson Space Center has become the world leader in human spaceflight operations. From the earliest programs - Mercury, Gemini, Apollo - through Skylab, Shuttle, ISS, and our Exploration initiatives, MOD and its predecessors have pioneered ops concepts and emphasized a history of mission leadership which has added value, maximized mission success, and built on continual improvement of the capabilities to become more efficient and effective. This paper provides specific examples that illustrate how MOD's focus on building and contributing value with diverse teams has been key to their successes both with the US space industry and the broader international community. This paper will discuss specific examples for the Plan, Train, Fly, and Facilities aspects within MOD. This paper also provides a discussion of the joint civil servant/contractor environment and the relative badge-less society within MOD. Several Shuttle mission related examples have also been included that encompass all of the aforementioned MOD elements and attributes, and are used to show significant MOD successes within the Shuttle Program. These examples include the STS-49 Intelsat recovery and repair, the (post-Columbia accident) TPS inspection process and the associated R-Bar Pitch Maneuver for ISS missions, and the STS-400 rescue mission preparation efforts for the Hubble Space Telescope repair mission. Since their beginning, MOD has consistently demonstrated their ability to evolve and respond to an ever changing environment, effectively prepare for the expected and successfully respond to the unexpected, and develop leaders, expertise, and a culture that has led to mission and Program success.

Spectroscopic factor and proton formation probability for the d3/2 proton emitter 151mLu

Directory of Open Access Journals (Sweden)

F. Wang

2017-07-01

Full Text Available The quenching of the experimental spectroscopic factor for proton emission from the short-lived d3/2 isomeric state in 151mLu was a long-standing problem. In the present work, proton emission from this isomer has been reinvestigated in an experiment at the Accelerator Laboratory of the University of Jyväskylä. The proton-decay energy and half-life of this isomer were measured to be 1295(5 keV and 15.4(8 μs, respectively, in agreement with another recent study. These new experimental data can resolve the discrepancy in the spectroscopic factor calculated using the spherical WKB approximation. Using the R-matrix approach it is found that the proton formation probability indicates no significant hindrance for the proton decay of 151mLu.

Fusion proton diagnostic for the C-2 field reversed configurationa)

Science.gov (United States)

Magee, R. M.; Clary, R.; Korepanov, S.; Smirnov, A.; Garate, E.; Knapp, K.; Tkachev, A.

2014-11-01

Measurements of the flux of fusion products from high temperature plasmas provide valuable insights into the ion energy distribution, as the fusion reaction rate is a very sensitive function of ion energy. In C-2, where field reversed configuration plasmas are formed by the collision of two compact toroids and partially sustained by high power neutral beam injection [M. Binderbauer et al., Phys. Rev. Lett. 105, 045003 (2010); M. Tuszewski et al., Phys. Rev. Lett. 108, 255008 (2012)], measurements of DD fusion neutron flux are used to diagnose ion temperature and study fast ion confinement and dynamics. In this paper, we will describe the development of a new 3 MeV proton detector that will complement existing neutron detectors. The detector is a large area (50 cm2), partially depleted, ion implanted silicon diode operated in a pulse counting regime. While the scintillator-based neutron detectors allow for high time resolution measurements (˜100 kHz), they have no spatial or energy resolution. The proton detector will provide 10 cm spatial resolution, allowing us to determine if the axial distribution of fast ions is consistent with classical fast ion theory or whether anomalous scattering mechanisms are active. We will describe in detail the diagnostic design and present initial data from a neutral beam test chamber.

The UV-VIS optical environment of the shuttle

Science.gov (United States)

Torr, M. R.

1985-01-01

During the Spacelab 1 shuttle mission, spectroscopic measurements were made of the atmospheric emissions over a broad wavelength range extending from the extreme ultraviolet to the near infrared. Those measurements were made under a variety of vehicle attitude and sunlight conditions. Superimposed on such spectra would be any features associated with the induced vehicle environment and its interaction with solar photons and the ambient neutral atmosphere and plasma. Various anomalies and unexpected features in the spectra from the perspective of possible shuttle-induced origins are discussed. The data indicate a dramatic cleanup of the vehicle environment over the course of the 10-day mission, a strong non-atmospheric red continuum underlying the spectra at night and at large angles to the velocity vector, and a variety of molecular band distributions which are not explained by the present understanding of the atmosphere.

The Space Shuttle and expendable launch systems - A U.S. commercial customer perspective

Science.gov (United States)

Savage, M.; Chagnon, R.

1985-10-01

The development of space transportation systems for commercial satellite launches is reviewed. A comparison of the Ariane system with the Space Shuttle is presented. The performance capability, reliability, and availability of the two systems are analyzed; the Ariane 4 is capable of launching payloads of 1900-4200 kg into transfer orbits and is better positioned than the Shuttle to handle commercial payloads greater than 1900 kg. The insurance costs, and spacecraft and launcher integration complexity for the two systems are discussed. The launch cost and postponement penalties are studied. NASA's launch cost is based on the length or mass of the payload multiplied by the fixed Shuttle cost, with Ariane attempting to keep prices $1-3 million lower, in order to be competitive with the Shuttle. NASA offers one free postponement and penalties as high as 55 percent; Ariane's penalties range from 6-18 percent of the launch price. The need for lower prices, an easier integration process, customer convience, and less severe postponement and reflight policies in order for the space transportation systems to be commercially useful, is discussed.

Local Equation of State for Protons, and Implications for Proton Heating in the Solar Wind.

Science.gov (United States)

Zaslavsky, A.; Maksimovic, M.; Kasper, J. C.

2017-12-01

The solar wind protons temperature is observed to decrease with distance to the Sun at a slower rate than expected from an adiabatic expansion law: the protons are therefore said to be heated. This observation raises the question of the evaluation of the heating rate, and the question of the heat source.These questions have been investigated by previous authors by gathering proton data on various distances to the Sun, using spacecraft as Helios or Ulysses, and then computing the radial derivative of the proton temperature in order to obtain a heating rate from the internal energy equation. The problem of such an approach is the computation of the radial derivative of the temperature profile, for which uncertainties are very large, given the dispersion of the temperatures measured at a given distance.An alternative approach, that we develop in this paper, consists in looking for an equation of state that links locally the pressure (or temperature) to the mass density. If such a relation exists then one can evaluate the proton heating rate on a local basis, without having any space derivative to compute.Here we use several years of STEREO and WIND proton data to search for polytropic equation of state. We show that such relationships are indeed a good approximation in given solar wind's velocity intervals and deduce the associated protons heating rates as a function of solar wind's speed. The obtained heating rates are shown to scale from around 1 kW/kg in the slow wind to around 10 kW/kg in the fast wind, in remarkable agreement with the rate of energy observed by previous authors to cascade in solar wind's MHD turbulence at 1 AU. These results therefore support the idea of proton turbulent heating in the solar wind.

The PIREX proton irradiation facility

Energy Technology Data Exchange (ETDEWEB)

Victoria, M. [Association EURATOM, Villigen (Switzerland)

1995-10-01

The proton Irradiation Experiment (PIREX) is a materials irradiation facility installed in a beam line of the 590 MeV proton accelerator at the Paul Scherrer Institute. Its main purpose is the testing of candidate materials for fusion reactor components. Protons of this energy produce simultaneously displacement damage and spallation products, amongst them helium and can therefore simulate any possible synergistic effects of damage and helium, that would be produced by the fusion neutrons.

The PIREX proton irradiation facility

International Nuclear Information System (INIS)

Victoria, M.

1995-01-01

The proton Irradiation Experiment (PIREX) is a materials irradiation facility installed in a beam line of the 590 MeV proton accelerator at the Paul Scherrer Institute. Its main purpose is the testing of candidate materials for fusion reactor components. Protons of this energy produce simultaneously displacement damage and spallation products, amongst them helium and can therefore simulate any possible synergistic effects of damage and helium, that would be produced by the fusion neutrons

Sea Quarks in the Proton

Directory of Open Access Journals (Sweden)

Reimer Paul E

2016-01-01

Full Text Available The proton is a composite particle in which the binding force is responsible for the majority of its mass. To understand this structure, the distributions and origins of the quark-antiquark pairs produced by the strong force must be measured. The SeaQuest collaboration is using the Drell-Yan process to elucidate antiquark distributions in the proton and to study their modification when the proton is held within a nucleus.

HAL/S programmer's guide. [for space shuttle project

Science.gov (United States)

Newbold, P. M.; Hotz, R. L.

1974-01-01

The structure and symbology of the HAL/S programming language are described; this language is to be used among the flight software for the space shuttle project. The data declaration, input/output statements, and replace statements are also discussed.

Feasibility of proton-activated implantable markers for proton range verification using PET

Science.gov (United States)

Cho, Jongmin; Ibbott, Geoffrey; Gillin, Michael; Gonzalez-Lepera, Carlos; Titt, Uwe; Paganetti, Harald; Kerr, Matthew; Mawlawi, Osama

2013-11-01

Proton beam range verification using positron emission tomography (PET) currently relies on proton activation of tissue, the products of which decay with a short half-life and necessitate an on-site PET scanner. Tissue activation is, however, negligible near the distal dose fall-off region of the proton beam range due to their high interaction energy thresholds. Therefore Monte Carlo simulation is often supplemented for comparison with measurement; however, this also may be associated with systematic and statistical uncertainties. Therefore, we sought to test the feasibility of using long-lived proton-activated external materials that are inserted or infused into the target volume for more accurate proton beam range verification that could be performed at an off-site PET scanner. We irradiated samples of ≥98% 18O-enriched water, natural Cu foils, and >97% 68Zn-enriched foils as candidate materials, along with samples of tissue-equivalent materials including 16O water, heptane (C7H16), and polycarbonate (C16H14O3)n, at four depths (ranging from 100% to 3% of center of modulation (COM) dose) along the distal fall-off of a modulated 160 MeV proton beam. Samples were irradiated either directly or after being embedded in Plastic Water® or balsa wood. We then measured the activity of the samples using PET imaging for 20 or 30 min after various delay times. Measured activities of candidate materials were up to 100 times greater than those of the tissue-equivalent materials at the four distal dose fall-off depths. The differences between candidate materials and tissue-equivalent materials became more apparent after longer delays between irradiation and PET imaging, due to the longer half-lives of the candidate materials. Furthermore, the activation of the candidate materials closely mimicked the distal dose fall-off with offsets of 1 to 2 mm. Also, signals from the foils were clearly visible compared to the background from the activated Plastic Water® and balsa wood

Giving Protons a Boost

CERN Multimedia

2004-01-01

The first of LHC's superconducting radio-frequency cavity modules has passed its final test at full power in the test area of building SM18. These modules carry an oscillating electric field that will accelerate protons around the LHC ring and help maintain the stability of the proton beams.

External proton and Li beams

International Nuclear Information System (INIS)

Schuff, Juan A.; Burlon, Alejandro A.; Debray, Mario E.; Kesque, Jose M.; Kreiner, Andres J.; Stoliar, Pablo A.; Naab, Fabian; Ozafran, Mabel J.; Vazquez, Monica E.; Perez de la Hoz, A.; Somacal, Hector; Valda, Alejandro; Canevas, S.; Ruffolo, M.; Tasat, D.R.; Muhlmann, M. C.

2000-01-01

In the frame of a feasibility study to introduce proton therapy in Argentina in a collaborative agreement between the Physics and Radiobiology Departments of the National Atomic Energy Commission or Argentina and the Centre de Protontherapie de Orsay, France, external proton and Li beams were produced at the TANDAR accelerator in Buenos Aires. The specific aim of this work was to start radiobiology studies on cell cultures and small laboratory animals. In particular we seek to determine here the relative biological effectiveness, RBE, for proton and Li beams as a function of energy for different tumor and normal cell lines. The 24 MeV proton beam was diffused using a 25 μm gold foil and extracted through a Kapton window to obtain a homogeneous field (constant to 95%) of about 7 cm in diameter. Measurements were carried out with quasi-monoenergetic beams (of 20.2 ± 0.07 MeV, 2.9 ± 0.10 MeV y 1.5 ± 0.1 MeV for protons and 21.4 ± 0.4 MeV for Lithium). Proton fluence and Bragg peaks were measured. The dose delivered in each case was monitored on-line with a calibrated transmission ionization chamber. Three cell lines PDV, PDVC 57 and V 79 (as a reference) were irradiated with γ-rays, proton and lithium beams with linear energy transfer (LET) from 2 to 100 keV/μm. RBE values in the range of 1.2-5.9 were obtained. In addition preliminary studies on chromosomal aberrations and viability of alveolar macrophages were carried out. (author)

Photoproduction of vector mesons in proton-proton ultraperipheral collisions at the CERN Large Hadron Collider

Science.gov (United States)

Xie, Ya-Ping; Chen, Xurong

2018-05-01

Photoproduction of vector mesons is computed with dipole model in proton-proton ultraperipheral collisions (UPCs) at the CERN Large Hadron Collider (LHC). The dipole model framework is employed in the calculations of vector mesons production in diffractive processes. Parameters of the bCGC model are refitted with the latest inclusive deep inelastic scattering experimental data. Employing the bCGC model and boosted Gaussian light-cone wave function for vector mesons, we obtain the prediction of rapidity distributions of J/ψ and ψ(2s) mesons in proton-proton ultraperipheral collisions at the LHC. The predictions give a good description of the experimental data of LHCb. Predictions of ϕ and ω mesons are also evaluated in this paper.

An experiment for Shuttle aerodynamic force coefficient determination from inflight dynamical and atmospheric measurements

Science.gov (United States)

Compton, H. R.; Blanchard, R. C.; Walberg, G. D.

1978-01-01

A two-phase experiment is proposed which utilizes the Shuttle Orbiter and its unique series of repeated entries into the earth's atmosphere as an airborne in situ aerodynamic testing laboratory. The objective of the experiment is to determine static aerodynamic force coefficients, first of the orbiter, and later of various entry configurations throughout the high speed flight regime, including the transition from free molecule to continuum fluid flow. The objective will be accomplished through analysis of inflight measurements from both shuttle-borne and shuttle-launched instrumented packages. Results are presented to demonstrate the feasibility of such an experiment.

Cost prediction model for various payloads and instruments for the Space Shuttle Orbiter

Science.gov (United States)

Hoffman, F. E.

1984-01-01

The following cost parameters of the space shuttle were undertaken: (1) to develop a cost prediction model for various payload classes of instruments and experiments for the Space Shuttle Orbiter; and (2) to show the implications of various payload classes on the cost of: reliability analysis, quality assurance, environmental design requirements, documentation, parts selection, and other reliability enhancing activities.

STS-26 MS Hilmers on fixed based (FB) shuttle mission simulator (SMS) middeck

Science.gov (United States)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) David C. Hilmers prepares to ascend a ladder representing the interdeck access hatch from the shuttle middeck to the flight deck. The STS-26 crew is training in the fixed base (FB) shuttle mission simulator (SMS) located in JSC Mission Simulation and Training Facility Bldg 5.

Charm production in proton-proton collisions at the LHC with the ALICE detector

CERN Document Server

Rossi, Andrea

The ALICE experiment at CERN will study the medium formed in very high energy lead-lead collisions at the LHC. According to the Quantum Chromo Dynamics theory of the strong interaction, a phase transition to a state where quarks and gluons are not confined into hadrons (Quark-Gluon Plasma) can occur in these collisions. Heavy quarks (charm and beauty) are produced in hard scattering processes in the first stages of the collisions. While travelling through the medium they can lose energy by means of gluon radiation. This affects the momentum spectra of the hadrons produced in the subsequent hadronization. To study the energy loss mechanism and its dependence on the parton nature (quark/gluon) and mass (light/heavy quark), hadron momentum spectra observed in heavy-ion collisions are compared to the same spectra observed in proton-proton collisions, where the formation of a thermalized medium is not expected. In this thesis, the measurement of charm production in proton-proton collisions via the exclusive recons...

Space Shuttle 750 psi Helium Regulator Application on Mars Science Laboratory Propulsion

Science.gov (United States)

Mizukami, Masashi; Yankura, George; Rust, Thomas; Anderson, John R.; Dien, Anthony; Garda, Hoshang; Bezer, Mary Ann; Johnson, David; Arndt, Scott

2009-01-01

The Mars Science Laboratory (MSL) is NASA's next major mission to Mars, to be launched in September 2009. It is a nuclear powered rover designed for a long duration mission, with an extensive suite of science instruments. The descent and landing uses a unique 'skycrane' concept, where a rocket-powered descent stage decelerates the vehicle, hovers over the ground, lowers the rover to the ground on a bridle, then flies a safe distance away for disposal. This descent stage uses a regulated hydrazine propulsion system. Performance requirements for the pressure regulator were very demanding, with a wide range of flow rates and tight regulated pressure band. These indicated that a piloted regulator would be needed, which are notoriously complex, and time available for development was short. Coincidentally, it was found that the helium regulator used in the Space Shuttle Orbiter main propulsion system came very close to meeting MSL requirements. However, the type was out of production, and fabricating new units would incur long lead times and technical risk. Therefore, the Space Shuttle program graciously furnished three units for use by MSL. Minor modifications were made, and the units were carefully tuned to MSL requirements. Some of the personnel involved had built and tested the original shuttle units. Delta qualification for MSL application was successfully conducted on one of the units. A pyrovalve slam start and shock test was conducted. Dynamic performance analyses for the new application were conducted, using sophisticated tools developed for Shuttle. Because the MSL regulator is a refurbished Shuttle flight regulator, it will be the only part of MSL which has physically already been in space.

The effect of flavin electron shuttles in microbial fuel cells current production

Energy Technology Data Exchange (ETDEWEB)

Velasquez-Orta, Sharon B. [Newcastle Univ., Newcastle upon Tyne (United Kingdom). School of Civil Engineering and Geosciences; Newcastle Univ., Newcastle upon Tyne (United Kingdom). School of Chemical Engineering and Advanced Materials; Head, Ian M.; Curtis, Thomas P. [Newcastle Univ., Newcastle upon Tyne (United Kingdom). School of Civil Engineering and Geosciences; Scott, Keith [Newcastle Univ., Newcastle upon Tyne (United Kingdom). School of Chemical Engineering and Advanced Materials; Lloyd, Jonathan R.; Canstein, Harald von [Manchester Univ. (United Kingdom). School of Earth, Atmospheric and Environmental Sciences

2010-02-15

The effect of electron shuttles on electron transfer to microbial fuel cell (MFC) anodes was studied in systems where direct contact with the anode was precluded. MFCs were inoculated with Shewanella cells, and flavins used as the electron shuttling compound. In MFCs with no added electron shuttles, flavin concentrations monitored in the MFCs' bulk liquid increased continuously with FMN as the predominant flavin. The maximum concentrations were 0.6 {mu}M for flavin mononucleotide and 0.2 {mu}M for riboflavin. In MFCs with added flavins, micro-molar concentrations were shown to increase current and power output. The peak current was at least four times higher in MFCs with high concentrations of flavins (4.5-5.5 {mu}M) than in MFCs with low concentrations (0.2-0.6 {mu}M). Although high power outputs (around 150 mW/m{sup 2}) were achieved in MFCs with high concentrations of flavins, a Clostridium-like bacterium along with other reactor limitations affected overall coulombic efficiencies (CE) obtained, achieving a maximum CE of 13%. Electron shuttle compounds (flavins) permitted bacteria to utilise a remote electron acceptor (anode) that was not accessible to the cells allowing current production until the electron donor (lactate) was consumed. (orig.)

Search for proton decay: introduction

International Nuclear Information System (INIS)

Goldhaber, M.

1984-01-01

In interpreting contained events observed in various proton decay detectors one can sometimes postulate, though usually not unambiguously, a potential decay mode of the proton, called a candidate. It is called a candidate, because for any individual event it is not possible to exclude the possibility that it is instead due to cosmic ray background, chiefly atmospheric neutrinos. Some consistency checks are proposed which could help establish proton decay, if it does occur in the presently accessible lifetime window

Triple parton scatterings in high-energy proton-proton collisions arXiv

CERN Document Server

d'Enterria, David

2017-01-01

A generic expression to compute triple parton scattering cross sections in high-energy proton-proton (pp) collisions is presented as a function of the corresponding single parton cross sections and the transverse parton profile of the proton encoded in an effective parameter σeff,TPS. The value of σeff,TPS is closely related to the similar effective cross section that characterizes double parton scatterings, and amounts to σeff,TPS=12.5±4.5  mb. Estimates for triple charm (cc¯) and bottom (bb¯) production in pp collisions at LHC and FCC energies are presented based on next-to-next-to-leading-order perturbative calculations for single cc¯, bb¯ cross sections. At s≈100  TeV, about 15% of the pp collisions produce three cc¯ pairs from three different parton-parton scatterings.

Cyclic Dipeptide Shuttles as a Novel Skin Penetration Enhancement Approach: Preliminary Evaluation with Diclofenac

Science.gov (United States)

Namjoshi, Sarika; Giralt, Ernest; Benson, Heather

2016-01-01

This study demonstrates the effectiveness of a peptide shuttle in delivering diclofenac into and through human epidermis. Diclofenac was conjugated to a novel phenylalanyl-N-methyl-naphthalenylalanine-derived diketopiperazine (DKP) shuttle and to TAT (a classical cell penetrating peptide), and topically applied to human epidermis in vitro. DKP and TAT effectively permeated into and through human epidermis. When conjugated to diclofenac, both DKP and TAT enhanced delivery into and through human epidermis, though DKP was significantly more effective. Penetration of diclofenac through human epidermis (to receptor) was increased by conjugation to the peptide shuttle and cell penetrating peptide with enhancement of 6x by DKP-diclofenac and 3x by TAT-diclofenac. In addition, the amount of diclofenac retained within the epidermis was significantly increased by peptide conjugation. COX-2 inhibition activity of diclofenac was retained when conjugated to DKP. Our study suggests that the peptide shuttle approach may offer a new strategy for targeted delivery of small therapeutic and diagnostic molecules to the skin. PMID:27548780

Study on patient-induced radioactivity during proton treatment in hengjian proton medical facility

International Nuclear Information System (INIS)

Wu, Qingbiao; Wang, Qingbin; Liang, Tianjiao; Zhang, Gang; Ma, Yinglin; Chen, Yu; Ye, Rong; Liu, Qiongyao; Wang, Yufei; Wang, Huaibao

2016-01-01

At present, increasingly more proton medical facilities have been established globally for better curative effect and less side effect in tumor treatment. Compared with electron and photon, proton delivers more energy and dose at its end of range (Bragg peak), and has less lateral scattering for its much larger mass. However, proton is much easier to produce neutron and induced radioactivity, which makes radiation protection for proton accelerators more difficult than for electron accelerators. This study focuses on the problem of patient-induced radioactivity during proton treatment, which has been ignored for years. However, we confirmed it is a vital factor for radiation protection to both patient escort and positioning technician, by FLUKA’s simulation and activation formula calculation of Hengjian Proton Medical Facility (HJPMF), whose energy ranges from 130 to 230 MeV. Furthermore, new formulas for calculating the activity buildup process of periodic irradiation were derived and used to study the relationship between saturation degree and half-life of nuclides. Finally, suggestions are put forward to lessen the radiation hazard from patient-induced radioactivity. - Highlights: • A detailed study on patient-induced radioactivity was conducted by adopting Monte Carlo code FLUKA and activation formula. • New formulas for calculating the activity build-up process of periodic irradiation were derived and extensively studied. • Patient induced radioactivity, which has been ignored for years, is confirmed as a vital factor for radiation protection. • The induced radioactivity from single short-time treatment and long-time running (saturation) were studied and compared. • Some suggestions on how to reduce the hazard of patient’s induced radioactivity were given.

WE-D-BRB-01: Basic Physics of Proton Therapy

Energy Technology Data Exchange (ETDEWEB)

Arjomandy, B. [McLaren Cancer Institute (United States)

2016-06-15

The goal of this session is to review the physics of proton therapy, treatment planning techniques, and the use of volumetric imaging in proton therapy. The course material covers the physics of proton interaction with matter and physical characteristics of clinical proton beams. It will provide information on proton delivery systems and beam delivery techniques for double scattering (DS), uniform scanning (US), and pencil beam scanning (PBS). The session covers the treatment planning strategies used in DS, US, and PBS for various anatomical sites, methods to address uncertainties in proton therapy and uncertainty mitigation to generate robust treatment plans. It introduces the audience to the current status of image guided proton therapy and clinical applications of CBCT for proton therapy. It outlines the importance of volumetric imaging in proton therapy. Learning Objectives: Gain knowledge in proton therapy physics, and treatment planning for proton therapy including intensity modulated proton therapy. The current state of volumetric image guidance equipment in proton therapy. Clinical applications of CBCT and its advantage over orthogonal imaging for proton therapy. B. Teo, B.K Teo had received travel funds from IBA in 2015.

WE-D-BRB-01: Basic Physics of Proton Therapy

International Nuclear Information System (INIS)

Arjomandy, B.

2016-01-01

The goal of this session is to review the physics of proton therapy, treatment planning techniques, and the use of volumetric imaging in proton therapy. The course material covers the physics of proton interaction with matter and physical characteristics of clinical proton beams. It will provide information on proton delivery systems and beam delivery techniques for double scattering (DS), uniform scanning (US), and pencil beam scanning (PBS). The session covers the treatment planning strategies used in DS, US, and PBS for various anatomical sites, methods to address uncertainties in proton therapy and uncertainty mitigation to generate robust treatment plans. It introduces the audience to the current status of image guided proton therapy and clinical applications of CBCT for proton therapy. It outlines the importance of volumetric imaging in proton therapy. Learning Objectives: Gain knowledge in proton therapy physics, and treatment planning for proton therapy including intensity modulated proton therapy. The current state of volumetric image guidance equipment in proton therapy. Clinical applications of CBCT and its advantage over orthogonal imaging for proton therapy. B. Teo, B.K Teo had received travel funds from IBA in 2015.

Proton-beam radiation therapy dosimetry standardization

International Nuclear Information System (INIS)

Gall, K.P.

1995-01-01

Beams of protons have been used for radiation therapy applications for over 40 years. In the last decade the number of facilities treating patients and the total number of patients being treated has begun go grow rapidly. Due to the limited and experimental nature of the early programs, dosimetry protocols tended to be locally defined. With the publication of the AAPM Task Group 20 report open-quotes Protocol for Dosimetry of Heavy Charged Particlesclose quotes and the open-quotes European Code of Practice for Proton-Beam Dosimetryclose quotes the practice of determining dose in proton-beam therapy was somewhat unified. The ICRU has also recently commissioned a report on recommendations for proton-beam dosimetry. There have been three main methods of determining proton dose; the Faraday cup technique, the ionization chamber technique, and the calorimeter technique. For practical reasons the ionization chamber technique has become the most widely used. However, due to large errors in basic parameters (e.g., W-value) is also has a large uncertainty for absolute dose. It has been proposed that the development of water calorimeter absorbed dose standards would reduce the uncertainty in absolute proton dose as well as the relative dose between megavoltage X-ray beams and proton beams. The advantages and disadvantages are discussed

On the Significance of the Upcoming Large Hadron Collider Proton-Proton Cross Section Data

Directory of Open Access Journals (Sweden)

Comay E.

2010-04-01

Full Text Available The relevance of the Regular Charge-Monopole Theory to the proton structure is described. The discussion relies on classicalelectrodynamics and its associated quantum mechanics. Few experimental data are used as a clue to the specific structure of baryons. This basis provides an explanation for the shape of the graph of the pre-LHC proton-proton cross section data. These data also enable a description of the significance of the expected LHC cross section measurements which will be known soon. Problematic QCD issues are pointed out.

Progresses in proton radioactivity studies

Energy Technology Data Exchange (ETDEWEB)

Ferreira, L. S., E-mail: flidia@ist.utl.pt [Center of Physics and Engineering of Advanced Materials, CeFEMA and Departamento de Física, Instituto Superior Técnico, Universidade de Lisboa, Avenida Rovisco Pais, P1049-001 Lisbon (Portugal); Maglione, E. [Dipartimento di Fisica e Astronomia “G. Galilei”, Via Marzolo 8, I-35131 Padova, Italy and Istituto Nazionale di Fisica Nucleare, Padova (Italy)

2016-07-07

In the present talk, we will discuss recent progresses in the theoretical study of proton radioactivity and their impact on the present understanding of nuclear structure at the extremes of proton stability.

Space Shuttle Guidance, Navigation, and Rendezvous Knowledge Capture Reports. Revision 1

Science.gov (United States)

Goodman, John L.

2011-01-01

This document is a catalog and readers guide to lessons learned, experience, and technical history reports, as well as compilation volumes prepared by United Space Alliance personnel for the NASA/Johnson Space Center (JSC) Flight Dynamics Division.1 It is intended to make it easier for future generations of engineers to locate knowledge capture documentation from the Shuttle Program. The first chapter covers observations on documentation quality and research challenges encountered during the Space Shuttle and Orion programs. The second chapter covers the knowledge capture approach used to create many of the reports covered in this document. These chapters are intended to provide future flight programs with insight that could be used to formulate knowledge capture and management strategies. The following chapters contain descriptions of each knowledge capture report. The majority of the reports concern the Space Shuttle. Three are included that were written in support of the Orion Program. Most of the reports were written from the years 2001 to 2011. Lessons learned reports concern primarily the shuttle Global Positioning System (GPS) upgrade and the knowledge capture process. Experience reports on navigation and rendezvous provide examples of how challenges were overcome and how best practices were identified and applied. Some reports are of a more technical history nature covering navigation and rendezvous. They provide an overview of mission activities and the evolution of operations concepts and trajectory design. The lessons learned, experience, and history reports would be considered secondary sources by historians and archivists.

Definition of Life Sciences laboratories for shuttle/Spacelab. Volume 1: Executive summary

Science.gov (United States)

1975-01-01

Research requirements and the laboratories needed to support a Life Sciences research program during the shuttle/Spacelab era were investigated. A common operational research equipment inventory was developed to support a comprehensive but flexible Life Sciences program. Candidate laboratories and operational schedules were defined and evaluated in terms of accomodation with the Spacelab and overall program planning. Results provide a firm foundation for the initiation of a life science program for the shuttle era.

Microscopic models for proton transfer in water and strongly hydrogen-bonded complexes with a single-well proton potential

DEFF Research Database (Denmark)

Kuznetsov, A.M.; Ulstrup, Jens

2004-01-01

A new mechanism and formalism for proton transfer in donor-acceptor complexes with long hydrogen bonds introduced recently [1], is applied to a proton transfer in liquid water. "Structural diffusion" of hydroxonium ions is regarded as totally adiabatic process, with synchronous hindered translation...... of two closest water molecules to and from the reaction complex as crucial steps. The water molecules induce a "gated" shift of the proton from the donor to the acceptor in the double-well potential with simultaneous breaking/formation of hydrogen bonds between these molecules and the proton donor...... and acceptor. The short-range and long-range proton transfer as "structural diffusion" of Zundel complexes is also considered. The theoretical formalism is illustrated with the use of Morse, exponential, and harmonic molecular potentials. This approach is extended to proton transfer in strongly hydrogen...

High temperature proton exchange membranes prepared from epoxycyclohexylethyltrimethoxysilane and amino trimethylene phosphonic acid as anhydrous proton conductors

International Nuclear Information System (INIS)

Chen, Cheng; Shen, Chunhui; Kong, Gengjin; Gao, Shanjun

2013-01-01

High temperature anhydrous proton exchange membranes based on phosphonic acid were prepared from epoxycyclohexylethyltrimethoxysilane (EHTMS) and amino trimethylene phosphonic acid (ATMP) by sol–gel process. The structures and properties of membranes with different phosphonic acid content were extensively characterized by FTIR, TG-DSC and XRD. Their proton conductivity under dry condition was also investigated under different temperature. The results show that the proton conductivity of the prepared membranes strongly depends on temperature, and the proton conductivity ranges from 8.81 × 10 −5 S cm −1 at 20 °C to 4.65 × 10 −2 S cm −1 at 140 °C under anhydrous condition. It indicates that the increasing temperature is favorable for congregating of the grafted–PO 3 H 2 and increasing of the proton mobility. In addition, from the results of AFM images, it was confirmed that the continuous distribution of phosphonic acid groups is favorable for the formation of the proton transport channel, which can significantly enhance the proton conductivity of the membranes. Highlights: ► Hybrid membranes of Epoxycyclohexylethyltrimethoxysilane and Amino trimethylene phosphonic acid. ► The proton conductivity is 4.65 × 10 −2 S cm −1 at 140 °C under anhydrous condition. ► Continuous uniform distributions of phosphonic acid groups can be observed by AFM. ► There could be hydrogen bond network within high temperature membranes

High temperature proton exchange membranes prepared from epoxycyclohexylethyltrimethoxysilane and amino trimethylene phosphonic acid as anhydrous proton conductors

Energy Technology Data Exchange (ETDEWEB)

Chen, Cheng [Department of Polymer Materials and Engineering, School of Material Science and Engineering, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan 430070 (China); Shen, Chunhui, E-mail: shenchunhui@whut.edu.cn [Department of Polymer Materials and Engineering, School of Material Science and Engineering, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan 430070 (China); Kong, Gengjin; Gao, Shanjun [Department of Polymer Materials and Engineering, School of Material Science and Engineering, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan 430070 (China)

2013-06-15

High temperature anhydrous proton exchange membranes based on phosphonic acid were prepared from epoxycyclohexylethyltrimethoxysilane (EHTMS) and amino trimethylene phosphonic acid (ATMP) by sol–gel process. The structures and properties of membranes with different phosphonic acid content were extensively characterized by FTIR, TG-DSC and XRD. Their proton conductivity under dry condition was also investigated under different temperature. The results show that the proton conductivity of the prepared membranes strongly depends on temperature, and the proton conductivity ranges from 8.81 × 10{sup −5} S cm{sup −1} at 20 °C to 4.65 × 10{sup −2} S cm{sup −1} at 140 °C under anhydrous condition. It indicates that the increasing temperature is favorable for congregating of the grafted–PO{sub 3}H{sub 2} and increasing of the proton mobility. In addition, from the results of AFM images, it was confirmed that the continuous distribution of phosphonic acid groups is favorable for the formation of the proton transport channel, which can significantly enhance the proton conductivity of the membranes. Highlights: ► Hybrid membranes of Epoxycyclohexylethyltrimethoxysilane and Amino trimethylene phosphonic acid. ► The proton conductivity is 4.65 × 10{sup −2} S cm{sup −1} at 140 °C under anhydrous condition. ► Continuous uniform distributions of phosphonic acid groups can be observed by AFM. ► There could be hydrogen bond network within high temperature membranes.

Measuring the contribution of low Bjorken-x gluons to the proton spin with polarized proton-proton collisions

Science.gov (United States)

Wolin, Scott Justin

The PHENIX experiment is one of two detectors located at the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory in Upton, NY. Understanding the spin structure of the proton is a central goal at RHIC, the only polarized proton-on-proton collider in existence. The PHENIX spin program has two primary objectives. The first is to improve the constraints on the polarized parton distributions of the anti-u and anti-d quarks within the proton. The second objective is to improve the constraint on the gluon spin contribution to the proton spin, DeltaG. The focus of this thesis is the second objective. PHENIX experiment has been successful at providing the first meaningful constraints on DeltaG, along with STAR, the other detector located at RHIC. These constraints have, in fact, eliminated the extreme scenarios for gluon polarization through measurements of the double spin asymmetry, ALL, between the cross section of like and unlike sign helicity pp interactions. ALL measurements can be performed with a variety of final states at PHENIX. Until 2009, these final states were only measured for pseudo-rapidities of |eta| Piston Calorimeter (MPC) was installed in 2006 and 2007 at forward rapidity, 3.1 < |eta| < 3.9, with the intention of giving PHENIX the ability to constrain Delta g(x) for x < 0.05. Following this, an electronics upgrade to the MPC will be described which enables the selection of events with two hadrons detected in the MPC. This requirement favors gluons at even lower x than the single hadron event selection. The di-hadron measurement that this upgrade makes possible will allow PHENIX to produce an ALL measurement that constrains Deltag(x) in the range of 5 x 10-4 < x < 0.01. Finally, we discuss the most important systematic uncertainty common to all ALL measurements which arises from the determination of the relative luminosity. A precision ALLL measurement requires measuring the final state yield from the portions of the proton beams that

Proton irradiation effects on organic polymers

International Nuclear Information System (INIS)

Seguchi, T.; Sasuga, T.; Kawakami, W.; Hagiwara, M.; Kohno, I.; Kamitsubo, H.

1987-01-01

Organic polymer films(100 μm thickness) of polyethylene, polypropylene, polyethyleneterephtalate, and polyethersulfone were irradiated by protons of 8 MeV using a cyclotron, and their radiation effects were investigated by the changes of mechanical properties. In order to irradiate protons uniformly over wide area of polymer films, specimens were scanned during proton irradiation using a special apparatus. The absorbed dose was measured by CTA and RCD film dosimeters, and can be determined that 1 μC/cm 2 of 8 MeV proton fluence is equivalent to 54 kGy. For polyethylene and polypropylene, there was no significant difference between proton and electron irradiation for same doses. However, for polyethersulfone the decay of mechanical property was observed to be less than that of irradiation by electron. (author)

Separation of the Shuttle Columbia's external fuel tank

Science.gov (United States)

1981-01-01

Separation of the Shuttle Columbia's external fuel tank (ET), photographed by a camera in the umbilical bay. Camera was able to record the underside of the tank as the orbiter toward its earth-orbital mission and the fuel tank fell toward the earth.

International aerospace engineering: NASA shuttle and European Spacelab

Science.gov (United States)

Bilstein, R. E.

1981-01-01

NASA negotiations and contractual arrangements involving European space research organizations' participation in manned space operations and efforts in building Spacelab for the U.S. Reusable Space Shuttle are discussed. Some of the diplomatic and technical collaboration involved in the international effort is reviewed.

AstroBox: A novel detection system for very low-energy protons from β-delayed proton decay

Energy Technology Data Exchange (ETDEWEB)

Pollacco, E., E-mail: epollacco@cea.fr [IRFU, CEA Saclay, Gif-sur-Yvette (France); Trache, L. [Cyclotron Institute, Texas A and M University, College Station, TX 77843-3366 (United States); National Institute of Physics and Nuclear Engineering, Bucharest-Magurele, RO-077125 (Romania); Simmons, E.; Spiridon, A.; McCleskey, M. [Cyclotron Institute, Texas A and M University, College Station, TX 77843-3366 (United States); Roeder, B.T., E-mail: broeder@comp.tamu.edu [Cyclotron Institute, Texas A and M University, College Station, TX 77843-3366 (United States); Saastamoinen, A.; Tribble, R.E. [Cyclotron Institute, Texas A and M University, College Station, TX 77843-3366 (United States); Pascovici, G. [National Institute of Physics and Nuclear Engineering, Bucharest-Magurele, RO-077125 (Romania); Kebbiri, M.; Mols, J.P.; Raillot, M. [IRFU, CEA Saclay, Gif-sur-Yvette (France)

2013-09-21

An instrument, AstroBox, has been developed to perform low energy proton spectroscopy from β-delayed proton emitters of interest to astrophysics studies. Energetic precursor nuclei are identified and stopped in the gas volume of the detector. The subsequent β or β-proton decay traces ionized paths in the gas. The ionization electrons are drifted in an electric field and are amplified with a Micro Pattern Gas Amplifier Detector (MPGAD). The system was tested in-beam using the β-delayed proton-emitter {sup 23}Al, which was produced with the p({sup 24}Mg,{sup 23}Al)2n reaction and separated with the Momentum Achromat Recoil Spectrometer (MARS) at the Cyclotron Institute at Texas A and M University. Off-beam proton spectra have essentially no β background down to ∼100keV and have a resolution of ∼15keV (fwhm) for proton-decay lines at E{sub p}=197 and 255 keV. Lines with βp-branching as low as 0.02% are observed. In addition, the device also gives good mass and charge resolution for energetic heavy ions measured in-beam.

Final Results of Shuttle MMOD Impact Database

Science.gov (United States)

Hyde, J. L.; Christiansen, E. L.; Lear, D. M.

2015-01-01

The Shuttle Hypervelocity Impact Database documents damage features on each Orbiter thought to be from micrometeoroids (MM) or orbital debris (OD). Data is divided into tables for crew module windows, payload bay door radiators and thermal protection systems along with other miscellaneous regions. The combined number of records in the database is nearly 3000. Each database record provides impact feature dimensions, location on the vehicle and relevant mission information. Additional detail on the type and size of particle that produced the damage site is provided when sampling data and definitive spectroscopic analysis results are available. Guidelines are described which were used in determining whether impact damage is from micrometeoroid or orbital debris impact based on the findings from scanning electron microscopy chemical analysis. Relationships assumed when converting from observed feature sizes in different shuttle materials to particle sizes will be presented. A small number of significant impacts on the windows, radiators and wing leading edge will be highlighted and discussed in detail, including the hypervelocity impact testing performed to estimate particle sizes that produced the damage.

Principles and practice of proton beam therapy

CERN Document Server

Das, Indra J

2015-01-01

Commissioned by The American Association of Physicists in Medicine (AAPM) for their June 2015 Summer School, this is the first AAPM monograph printed in full color. Proton therapy has been used in radiation therapy for over 70 years, but within the last decade its use in clinics has grown exponentially. This book fills in the proton therapy gap by focusing on the physics of proton therapy, including beam production, proton interactions, biology, dosimetry, treatment planning, quality assurance, commissioning, motion management, and uncertainties. Chapters are written by the world's leading medical physicists who work at the pioneering proton treatment centers around the globe. They share their understandings after years of experience treating thousands of patients. Case studies involving specific cancer treatments show that there is some art to proton therapy as well as state-of-the-art science. Even though the focus lies on proton therapy, the content provided is also valuable to heavy charged particle th...

Space shuttle orbiter guidance, naviagation and control software functional requirements: Horizontal flight operations

Science.gov (United States)

1972-01-01

The shuttle GN&C software functions for horizontal flight operations are defined. Software functional requirements are grouped into two categories: first horizontal flight requirements and full mission horizontal flight requirements. The document privides the intial step in the shuttle GN&C software design process. It also serves as a management tool to identify analyses which are required to define requirements.

Can molecular diffusion explain Space Shuttle plume spreading?

Science.gov (United States)

Meier, R. R.; Plane, John M. C.; Stevens, Michael H.; Paxton, L. J.; Christensen, A. B.; Crowley, G.

2010-04-01

The satellite-borne Global Ultraviolet Imager (GUVI) has produced more than 20 images of NASA Space Shuttle main engine plumes in the lower thermosphere. These reveal atomic hydrogen and, by inference, water vapor transport over hemispherical-scale distances with speeds much faster than expected from models of thermospheric wind motions. Furthermore, the hydrogen plumes expand rapidly. We find rates that exceed the horizontal diffusion speed at nominal plume altitudes of 104-112 km. Kelley et al. (2009) have proposed a 2-D turbulence mechanism to explain the observed spreading rates (and rapid advection) of the plumes. But upon further investigation, we conclude that H atom diffusion can indeed account for the observed expansion rates by recognizing that vertical diffusion quickly conveys atoms to higher altitudes where horizontal diffusion is much more rapid. We also find evidence for H atom production directly during the Shuttle's main engine burn.

Acceleration of polarized proton beams

International Nuclear Information System (INIS)

Roser, T.

1998-01-01

The acceleration of polarized beams in circular accelerators is complicated by the numerous depolarizing spin resonances. Using a partial Siberian snake and a rf dipole that ensure stable adiabatic spin motion during acceleration has made it possible to accelerate polarized protons to 25 GeV at the Brookhaven AGS. Full Siberian snakes are being developed for RHIC to make the acceleration of polarized protons to 250 GeV possible. A similar scheme is being studied for the 800 GeV HERA proton accelerator

Ring current proton decay by charge exchange

Science.gov (United States)

Smith, P. H.; Hoffman, R. A.; Fritz, T.

1975-01-01

Explorer 45 measurements during the recovery phase of a moderate magnetic storm have confirmed that the charge exchange decay mechanism can account for the decay of the storm-time proton ring current. Data from the moderate magnetic storm of 24 February 1972 was selected for study since a symmetrical ring current had developed and effects due to asymmetric ring current losses could be eliminated. It was found that after the initial rapid decay of the proton flux, the equatorially mirroring protons in the energy range 5 to 30 keV decayed throughout the L-value range of 3.5 to 5.0 at the charge exchange decay rate calculated by Liemohn. After several days of decay, the proton fluxes reached a lower limit where an apparent equilibrium was maintained, between weak particle source mechanisms and the loss mechanisms, until fresh protons were injected into the ring current region during substorms. While other proton loss mechanisms may also be operating, the results indicate that charge exchange can entirely account for the storm-time proton ring current decay, and that this mechanism must be considered in all studies involving the loss of proton ring current particles.

Search for Sphalerons in Proton-Proton Collisions

CERN Document Server

Satco, Daria

2017-01-01

In view of new possibilities becoming more realistic with FCC design and of recent promising results regarding $(B+L)$-violating processes detection we concentrated our research on generation and analysis of sphaleron transitions. The existence of instanton and sphaleron solutions which are associated with transitions between different vacuum states is well known since 1980s. However first calculations of instanton rate killed any hope to detect them even at very high energies while the calculation of sphaleron transitions rate is a tricky problem which continue being widely discussed. In our research we used HERBVI package to generate baryon- and lepton-number violating processes in proton-proton collisions at typical energies 14, 33, 40 and 100 TeV in order to estimate the upper limit on the sphaleron cross-section. We considered the background processes and determined the zero background regions.

Prompt double J/ψ production in proton-proton collisions at the LHC

International Nuclear Information System (INIS)

Baranov, S.P.; Rezaeian, Amir H.

2015-11-01

We provide a detailed study of prompt double J/ψ production within the non-relativistic QCD (NRQCD) framework in proton-proton collisions at the LHC.We confront the recent LHC data with the results obtained at leading-order (LO) in the NRQCD framework within two approaches of the collinear factorization and the k T -factorization. We show that the LHCb data can be fairly described within the k T -factorized LO NRQCD, while the collinearly factorized LO NRQCD significantly overshoots the LHCb data at low J/ψ-pair invariant mass. We show that the LO NRQCD formalism cannot describe the recent CMS data, with about one order of magnitude discrepancy. If the CMS data are confirmed, this indicates rather large higher-order corrections for prompt double J/ψ production. We provide various predictions which can further test the NRQCD-based approach at the LHC in a kinematic region that LO contributions dominate. We also investigate long-range in rapidity double J/ψ correlations. We found no evidence of a ridge-like structure for double J/ψ production in proton-proton collisions at the LHC up to subleading α 6 s accuracy.

Measuring the Weak Charge of the Proton via Elastic Electron-Proton Scattering

Energy Technology Data Exchange (ETDEWEB)

Jones, Donald C. [Univ. of Virginia, Charlottesville, VA (United States)

2015-10-01

The Qweak experiment which ran in Hall C at Jefferson Lab in Newport News, VA, and completed data taking in May 2012, measured the weak charge of the proton Q^p_W via elastic electron-proton scattering. Longitudinally polarized electrons were scattered from an unpolarized liquid hydrogen target. The helicity of the electron beam was flipped at approximately 1 kHz between left and right spin states. The Standard Model predicts a small parity-violating asymmetry of scattering rates between right and left helicity states due to the weak interaction. An initial result using 4% of the data was published in October 2013 [1] with a measured parity-violating asymmetry of -279 ± 35(stat) ± 31 (syst) ppb. This asymmetry, along with other data from parity-violating electron scattering experiments, provided the world's first determination of the weak charge of the proton. The weak charge of the proton was found to be ^p_W = 0.064 ± 0.012, in good agreement with the Standard Model prediction of ^p_W(SM) = 0.0708 ± 0.0003[2].

Interaction Region for a 100 TeV Proton-Proton Collider

CERN Document Server

Martin, R; Dalena, B

2015-01-01

As part of its post-LHC high energy physics program, CERN is conducting a study for a new proton-proton collider, FCC-hh, running at center-of-mass energies of up to 100 TeV, pushing the energy frontier of fundamental physics to a new limit. At a circumference of 80-100 km, this machine is planned to use the same tunnel as FCC-ee, a proposed 90-350 GeV high luminosity electron-positron collider. This paper presents the design progress and technical challenges for the interaction region of FCC-hh.

Radiotherapy : proton therapy

International Nuclear Information System (INIS)

1991-01-01

The first phase of proton therapy at the National Accelerator Centre will be the development of a 200 MeV small-field horizontal beam radioneurosurgical facility in the south treatment vault. A progressive expansion of this facility is planned. The patient support and positioning system has been designed and developed by the Departments of Mechanical Engineering and Surveying of the University of Cape Town to ensure the accurate positioning in the proton beam of the lesion to be treated. The basic components of the system are an adjustable chair, a series of video cameras and two computers. The specifications for the proton therapy interlock system require that the inputs to and the outputs from the system be similar to those of the neutron therapy system. Additional facilities such as a full diagnostic system which would assist the operators in the event of an error will also be provided. Dosimeters are required for beam monitoring, for monitor calibration and for determining dose distributions. Several designs of transmission ionization chambers for beam monitoring have been designed and tested, while several types of ionization chambers and diodes have been used for the dose distribution measurements. To facilitate the comparison of measured ranges and energy losses of proton beams in the various materials with tabled values, simple empirical approximations, which are sufficiently accurate for most applications, have been used. 10 refs., 10 fig., 4 tabs

DIMETHYL ETHER (DME)-FUELED SHUTTLE BUS DEMONSTRATION PROJECT

Energy Technology Data Exchange (ETDEWEB)

Elana M. Chapman; Shirish Bhide; Jennifer Stefanik; Andre L. Boehman; David Klinikowski

2003-04-01

The objectives of this research and demonstration program are to convert a campus shuttle bus to operation on dimethyl ether, a potential ultra-clean alternative diesel fuel. To accomplish this objective, this project includes laboratory evaluation of a fuel conversion strategy, as well as, field demonstration of the DME-fueled shuttle bus. Since DME is a fuel with no lubricity (i.e., it does not possess the lubricating quality of diesel fuel), conventional fuel delivery and fuel injection systems are not compatible with dimethyl ether. Therefore, to operate a diesel engine on DME one must develop a fuel-tolerant injection system, or find a way to provide the necessary lubricity to the DME. In this project, they have chosen the latter strategy in order to achieve the objective with minimal need to modify the engine. The strategy is to blend DME with diesel fuel, to obtain the necessary lubricity to protect the fuel injection system and to achieve low emissions. The laboratory studies have included work with a Navistar V-8 turbodiesel engine, demonstration of engine operation on DME-diesel blends and instrumentation for evaluating fuel properties. The field studies have involved performance, efficiency and emissions measurements with the Champion Motorcoach ''Defender'' shuttle bus which will be converted to DME-fueling. The results include baseline emissions, performance and combustion measurements on the Navistar engine for operation on a federal low sulfur diesel fuel (300 ppm S). Most recently, they have completed engine combustion studies on DME-diesel blends up to 30 wt% DME addition.

Development of disease animal models using proton beam

International Nuclear Information System (INIS)

Nam, K. H.; Kim, E. K.; Kim, H. R.; Seo, Y. W.

2010-03-01

To identify proper proton beam dose for mutant mouse development, total 7 times of proton beam were performed. There are too low incidence of mutation in pup mouse which were derived embryos radiated by 1Gy proton beam. Some mutation could be identified in pup mice which were derived embryos radiated by 1.5-2.5Gy proton beam. Mouse embryos irradiated with 1-10Gy of proton beam were inhibited in their in vitro development to 2 cell stage. There was no pups born from embryos which were irradiated with proton beam over 3 Gy. Early mouse development were greatly inhibited by proton beam irradiation of over 10Gy when cultured in vitro. In conclusion, it is efficient to irradiate mouse embryo with 1.5-2.5Gy of proton beam for development of mutant mice

Measurement of pion, kaon and proton production in proton-proton collisions at [Formula: see text] TeV.

Science.gov (United States)

Adam, J; Adamová, D; Aggarwal, M M; Rinella, G Aglieri; Agnello, M; Agrawal, N; Ahammed, Z; Ahmed, I; Ahn, S U; Aimo, I; Aiola, S; Ajaz, M; Akindinov, A; Alam, S N; Aleksandrov, D; Alessandro, B; Alexandre, D; Molina, R Alfaro; Alici, A; Alkin, A; Alme, J; Alt, T; Altinpinar, S; Altsybeev, I; Prado, C Alves Garcia; Andrei, C; Andronic, A; Anguelov, V; Anielski, J; Antičić, T; Antinori, F; Antonioli, P; Aphecetche, L; Appelshäuser, H; Arcelli, S; Armesto, N; Arnaldi, R; Aronsson, T; Arsene, I C; Arslandok, M; Augustinus, A; Averbeck, R; Azmi, M D; Bach, M; Badalà, A; Baek, Y W; Bagnasco, S; Bailhache, R; Bala, R; Baldisseri, A; Ball, M; Pedrosa, F Baltasar Dos Santos; Baral, R C; Barbano, A M; Barbera, R; Barile, F; Barnaföldi, G G; Barnby, L S; Barret, V; Bartalini, P; Bartke, J; Bartsch, E; Basile, M; Bastid, N; Basu, S; Bathen, B; Batigne, G; Camejo, A Batista; Batyunya, B; Batzing, P C; Bearden, I G; Beck, H; Bedda, C; Behera, N K; Belikov, I; Bellini, F; Martinez, H Bello; Bellwied, R; Belmont, R; Belmont-Moreno, E; Belyaev, V; Bencedi, G; Beole, S; Berceanu, I; Bercuci, A; Berdnikov, Y; Berenyi, D; Bertens, R A; Berzano, D; Betev, L; Bhasin, A; Bhat, I R; Bhati, A K; Bhattacharjee, B; Bhom, J; Bianchi, L; Bianchi, N; Bianchin, C; Bielčík, J; Bielčíková, J; Bilandzic, A; Biswas, S; Bjelogrlic, S; Blanco, F; Blau, D; Blume, C; Bock, F; Bogdanov, A; Bøggild, H; Boldizsár, L; Bombara, M; Book, J; Borel, H; Borissov, A; Borri, M; Bossú, F; Botje, M; Botta, E; Böttger, S; Braun-Munzinger, P; Bregant, M; Breitner, T; Broker, T A; Browning, T A; Broz, M; Brucken, E J; Bruna, E; Bruno, G E; Budnikov, D; Buesching, H; Bufalino, S; Buncic, P; Busch, O; Buthelezi, Z; Buxton, J T; Caffarri, D; Cai, X; Caines, H; Diaz, L Calero; Caliva, A; Villar, E Calvo; Camerini, P; Carena, F; Carena, W; Castellanos, J Castillo; Castro, A J; Casula, E A R; Cavicchioli, C; Sanchez, C Ceballos; Cepila, J; Cerello, P; Chang, B; Chapeland, S; Chartier, M; Charvet, J L; Chattopadhyay, S; Chattopadhyay, S; Chelnokov, V; Cherney, M; Cheshkov, C; Cheynis, B; Barroso, V Chibante; Chinellato, D D; Chochula, P; Choi, K; Chojnacki, M; Choudhury, S; Christakoglou, P; Christensen, C H; Christiansen, P; Chujo, T; Chung, S U; Cicalo, C; Cifarelli, L; Cindolo, F; Cleymans, J; Colamaria, F; Colella, D; Collu, A; Colocci, M; Balbastre, G Conesa; Valle, Z Conesa Del; Connors, M E; Contreras, J G; Cormier, T M; Morales, Y Corrales; Maldonado, I Cortés; Cortese, P; Cosentino, M R; Costa, F; Crochet, P; Albino, R Cruz; Cuautle, E; Cunqueiro, L; Dahms, T; Dainese, A; Danu, A; Das, D; Das, I; Das, S; Dash, A; Dash, S; De, S; Caro, A De; Cataldo, G de; Cuveland, J de; Falco, A De; Gruttola, D De; Marco, N De; Pasquale, S De; Deisting, A; Deloff, A; Dénes, E; D'Erasmo, G; Bari, D Di; Mauro, A Di; Nezza, P Di; Corchero, M A Diaz; Dietel, T; Dillenseger, P; Divià, R; Djuvsland, Ø; Dobrin, A; Dobrowolski, T; Gimenez, D Domenicis; Dönigus, B; Dordic, O; Dubey, A K; Dubla, A; Ducroux, L; Dupieux, P; Ehlers, R J; Elia, D; Engel, H; Erazmus, B; Erhardt, F; Eschweiler, D; Espagnon, B; Estienne, M; Esumi, S; Eum, J; Evans, D; Evdokimov, S; Eyyubova, G; Fabbietti, L; Fabris, D; Faivre, J; Fantoni, A; Fasel, M; Feldkamp, L; Felea, D; Feliciello, A; Feofilov, G; Ferencei, J; Téllez, A Fernández; Ferreiro, E G; Ferretti, A; Festanti, A; Figiel, J; Figueredo, M A S; Filchagin, S; Finogeev, D; Fionda, F M; Fiore, E M; Fleck, M G; Floris, M; Foertsch, S; Foka, P; Fokin, S; Fragiacomo, E; Francescon, A; Frankenfeld, U; Fuchs, U; Furget, C; Furs, A; Girard, M Fusco; Gaardhøje, J J; Gagliardi, M; Gago, A M; Gallio, M; Gangadharan, D R; Ganoti, P; Gao, C; Garabatos, C; Garcia-Solis, E; Gargiulo, C; Gasik, P; Germain, M; Gheata, A; Gheata, M; Ghosh, P; Ghosh, S K; Gianotti, P; Giubellino, P; Giubilato, P; Dziadus, E Gladysz; Glässel, P; Ramirez, A Gomez; Zamora, P González; Gorbunov, S; Görlich, L; Gotovac, S; Grabski, V; Graczykowski, L K; Grelli, A; Grigoras, A; Grigoras, C; Grigoriev, V; Grigoryan, A; Grigoryan, S; Grinyov, B; Grion, N; Grosse-Oetringhaus, J F; Grossiord, J-Y; Grosso, R; Guber, F; Guernane, R; Guerzoni, B; Gulbrandsen, K; Gulkanyan, H; Gunji, T; Gupta, A; Gupta, R; Haake, R; Haaland, Ø; Hadjidakis, C; Haiduc, M; Hamagaki, H; Hamar, G; Hanratty, L D; Hansen, A; Harris, J W; Hartmann, H; Harton, A; Hatzifotiadou, D; Hayashi, S; Heckel, S T; Heide, M; Helstrup, H; Herghelegiu, A; Corral, G Herrera; Hess, B A; Hetland, K F; Hilden, T E; Hillemanns, H; Hippolyte, B; Hristov, P; Huang, M; Humanic, T J; Hussain, N; Hussain, T; Hutter, D; Hwang, D S; Ilkaev, R; Ilkiv, I; Inaba, M; Ionita, C; Ippolitov, M; Irfan, M; Ivanov, M; Ivanov, V; Izucheev, V; Jacobs, P M; Jahnke, C; Jang, H J; Janik, M A; Jayarathna, P H S Y; Jena, C; Jena, S; Bustamante, R T Jimenez; Jones, P G; Jung, H; Jusko, A; Kalinak, P; Kalweit, A; Kamin, J; Kang, J H; Kaplin, V; Kar, S; Uysal, A Karasu; Karavichev, O; Karavicheva, T; Karpechev, E; Kebschull, U; Keidel, R; Keijdener, D L D; Keil, M; Khan, K H; Khan, M M; Khan, P; Khan, S A; Khanzadeev, A; Kharlov, Y; Kileng, B; Kim, B; Kim, D W; Kim, D J; Kim, H; Kim, J S; Kim, M; Kim, M; Kim, S; Kim, T; Kirsch, S; Kisel, I; Kiselev, S; Kisiel, A; Kiss, G; Klay, J L; Klein, C; Klein, J; Klein-Bösing, C; Kluge, A; Knichel, M L; Knospe, A G; Kobayashi, T; Kobdaj, C; Kofarago, M; Köhler, M K; Kollegger, T; Kolojvari, A; Kondratiev, V; Kondratyeva, N; Kondratyuk, E; Konevskikh, A; Kouzinopoulos, C; Kovalenko, O; Kovalenko, V; Kowalski, M; Kox, S; Meethaleveedu, G Koyithatta; Kral, J; Králik, I; Kravčáková, A; Krelina, M; Kretz, M; Krivda, M; Krizek, F; Kryshen, E; Krzewicki, M; Kubera, A M; Kučera, V; Kucheriaev, Y; Kugathasan, T; Kuhn, C; Kuijer, P G; Kulakov, I; Kumar, J; Kumar, L; Kurashvili, P; Kurepin, A; Kurepin, A B; Kuryakin, A; Kushpil, S; Kweon, M J; Kwon, Y; Pointe, S L La; Rocca, P La; Fernandes, C Lagana; Lakomov, I; Langoy, R; Lara, C; Lardeux, A; Lattuca, A; Laudi, E; Lea, R; Leardini, L; Lee, G R; Lee, S; Legrand, I; Lehnert, J; Lemmon, R C; Lenti, V; Leogrande, E; Monzón, I León; Leoncino, M; Lévai, P; Li, S; Li, X; Lien, J; Lietava, R; Lindal, S; Lindenstruth, V; Lippmann, C; Lisa, M A; Ljunggren, H M; Lodato, D F; Loenne, P I; Loggins, V R; Loginov, V; Loizides, C; Lopez, X; Torres, E López; Lowe, A; Lu, X-G; Luettig, P; Lunardon, M; Luparello, G; Maevskaya, A; Mager, M; Mahajan, S; Mahmood, S M; Maire, A; Majka, R D; Malaev, M; Cervantes, I Maldonado; Malinina, L; Mal'Kevich, D; Malzacher, P; Mamonov, A; Manceau, L; Manko, V; Manso, F; Manzari, V; Marchisone, M; Mareš, J; Margagliotti, G V; Margotti, A; Margutti, J; Marín, A; Markert, C; Marquard, M; Martin, N A; Blanco, J Martin; Martinengo, P; Martínez, M I; Martínez García, G; Pedreira, M Martinez; Martynov, Y; Mas, A; Masciocchi, S; Masera, M; Masoni, A; Massacrier, L; Mastroserio, A; Masui, H; Matyja, A; Mayer, C; Mazer, J; Mazzoni, M A; Mcdonald, D; Meddi, F; Menchaca-Rocha, A; Meninno, E; Pérez, J Mercado; Meres, M; Miake, Y; Mieskolainen, M M; Mikhaylov, K; Milano, L; Milosevic, J; Minervini, L M; Mischke, A; Mishra, A N; Miśkowiec, D; Mitra, J; Mitu, C M; Mohammadi, N; Mohanty, B; Molnar, L; Zetina, L Montaño; Montes, E; Morando, M; Godoy, D A Moreira De; Moretto, S; Morreale, A; Morsch, A; Muccifora, V; Mudnic, E; Mühlheim, D; Muhuri, S; Mukherjee, M; Müller, H; Mulligan, J D; Munhoz, M G; Murray, S; Musa, L; Musinsky, J; Nandi, B K; Nania, R; Nappi, E; Naru, M U; Nattrass, C; Nayak, K; Nayak, T K; Nazarenko, S; Nedosekin, A; Nellen, L; Ng, F; Nicassio, M; Niculescu, M; Niedziela, J; Nielsen, B S; Nikolaev, S; Nikulin, S; Nikulin, V; Noferini, F; Nomokonov, P; Nooren, G; Norman, J; Nyanin, A; Nystrand, J; Oeschler, H; Oh, S; Oh, S K; Ohlson, A; Okatan, A; Okubo, T; Olah, L; Oleniacz, J; Silva, A C Oliveira Da; Oliver, M H; Onderwaater, J; Oppedisano, C; Velasquez, A Ortiz; Oskarsson, A; Otwinowski, J; Oyama, K; Ozdemir, M; Pachmayer, Y; Pagano, P; Paić, G; Pajares, C; Pal, S K; Pan, J; Pandey, A K; Pant, D; Papikyan, V; Pappalardo, G S; Pareek, P; Park, W J; Parmar, S; Passfeld, A; Paticchio, V; Paul, B; Pawlak, T; Peitzmann, T; Costa, H Pereira Da; Filho, E Pereira De Oliveira; Peresunko, D; Lara, C E Pérez; Peskov, V; Pestov, Y; Petráček, V; Petrov, V; Petrovici, M; Petta, C; Piano, S; Pikna, M; Pillot, P; Pinazza, O; Pinsky, L; Piyarathna, D B; Płoskoń, M; Planinic, M; Pluta, J; Pochybova, S; Podesta-Lerma, P L M; Poghosyan, M G; Polichtchouk, B; Poljak, N; Poonsawat, W; Pop, A; Porteboeuf-Houssais, S; Porter, J; Pospisil, J; Prasad, S K; Preghenella, R; Prino, F; Pruneau, C A; Pshenichnov, I; Puccio, M; Puddu, G; Pujahari, P; Punin, V; Putschke, J; Qvigstad, H; Rachevski, A; Raha, S; Rajput, S; Rak, J; Rakotozafindrabe, A; Ramello, L; Raniwala, R; Raniwala, S; Räsänen, S S; Rascanu, B T; Rathee, D; Razazi, V; Read, K F; Real, J S; Redlich, K; Reed, R J; Rehman, A; Reichelt, P; Reicher, M; Reidt, F; Ren, X; Renfordt, R; Reolon, A R; Reshetin, A; Rettig, F; Revol, J-P; Reygers, K; Riabov, V; Ricci, R A; Richert, T; Richter, M; Riedler, P; Riegler, W; Riggi, F; Ristea, C; Rivetti, A; Rocco, E; Cahuantzi, M Rodríguez; Manso, A Rodriguez; Røed, K; Rogochaya, E; Rohr, D; Röhrich, D; Romita, R; Ronchetti, F; Ronflette, L; Rosnet, P; Rossi, A; Roukoutakis, F; Roy, A; Roy, C; Roy, P; Montero, A J Rubio; Rui, R; Russo, R; Ryabinkin, E; Ryabov, Y; Rybicki, A; Sadovsky, S; Šafařík, K; Sahlmuller, B; Sahoo, P; Sahoo, R; Sahoo, S; Sahu, P K; Saini, J; Sakai, S; Saleh, M A; Salgado, C A; Salzwedel, J; Sambyal, S; Samsonov, V; Castro, X Sanchez; Šándor, L; Sandoval, A; Sano, M; Santagati, G; Sarkar, D; Scapparone, E; Scarlassara, F; Scharenberg, R P; Schiaua, C; Schicker, R; Schmidt, C; Schmidt, H R; Schuchmann, S; Schukraft, J; Schulc, M; Schuster, T; Schutz, Y; Schwarz, K; Schweda, K; Scioli, G; Scomparin, E; Scott, R; Seeder, K S; Seger, J E; Sekiguchi, Y; Selyuzhenkov, I; Senosi, K; Seo, J; Serradilla, E; Sevcenco, A; Shabanov, A; Shabetai, A; Shadura, O; Shahoyan, R; Shangaraev, A; Sharma, A; Sharma, N; Shigaki, K; Shtejer, K; Sibiriak, Y; Siddhanta, S; Sielewicz, K M; Siemiarczuk, T; Silvermyr, D; Silvestre, C; Simatovic, G; Simonetti, G; Singaraju, R; Singh, R; Singha, S; Singhal, V; Sinha, B C; Sinha, T; Sitar, B; Sitta, M; Skaali, T B; Slupecki, M; Smirnov, N; Snellings, R J M; Snellman, T W; Søgaard, C; Soltz, R; Song, J; Song, M; Song, Z; Soramel, F; Sorensen, S; Spacek, M; Spiriti, E; Sputowska, I; Stassinaki, M Spyropoulou; Srivastava, B K; Stachel, J; Stan, I; Stefanek, G; Steinpreis, M; Stenlund, E; Steyn, G; Stiller, J H; Stocco, D; Strmen, P; Suaide, A A P; Sugitate, T; Suire, C; Suleymanov, M; Sultanov, R; Šumbera, M; Symons, T J M; Szabo, A; Toledo, A Szanto de; Szarka, I; Szczepankiewicz, A; Szymanski, M; Takahashi, J; Tanaka, N; Tangaro, M A; Takaki, J D Tapia; Peloni, A Tarantola; Tariq, M; Tarzila, M G; Tauro, A; Muñoz, G Tejeda; Telesca, A; Terasaki, K; Terrevoli, C; Teyssier, B; Thäder, J; Thomas, D; Tieulent, R; Timmins, A R; Toia, A; Trogolo, S; Trubnikov, V; Trzaska, W H; Tsuji, T; Tumkin, A; Turrisi, R; Tveter, T S; Ullaland, K; Uras, A; Usai, G L; Utrobicic, A; Vajzer, M; Vala, M; Palomo, L Valencia; Vallero, S; Maarel, J Van Der; Hoorne, J W Van; Leeuwen, M van; Vanat, T; Vyvre, P Vande; Varga, D; Vargas, A; Vargyas, M; Varma, R; Vasileiou, M; Vasiliev, A; Vauthier, A; Vechernin, V; Veen, A M; Veldhoen, M; Velure, A; Venaruzzo, M; Vercellin, E; Limón, S Vergara; Vernet, R; Verweij, M; Vickovic, L; Viesti, G; Viinikainen, J; Vilakazi, Z; Baillie, O Villalobos; Vinogradov, A; Vinogradov, L; Vinogradov, Y; Virgili, T; Vislavicius, V; Viyogi, Y P; Vodopyanov, A; Völkl, M A; Voloshin, K; Voloshin, S A; Volpe, G; Haller, B von; Vorobyev, I; Vranic, D; Vrláková, J; Vulpescu, B; Vyushin, A; Wagner, B; Wagner, J; Wang, H; Wang, M; Wang, Y; Watanabe, D; Weber, M; Weber, S G; Wessels, J P; Westerhoff, U; Wiechula, J; Wikne, J; Wilde, M; Wilk, G; Wilkinson, J; Williams, M C S; Windelband, B; Winn, M; Yaldo, C G; Yamaguchi, Y; Yang, H; Yang, P; Yano, S; Yasnopolskiy, S; Yin, Z; Yokoyama, H; Yoo, I-K; Yurchenko, V; Yushmanov, I; Zaborowska, A; Zaccolo, V; Zaman, A; Zampolli, C; Zanoli, H J C; Zaporozhets, S; Zarochentsev, A; Závada, P; Zaviyalov, N; Zbroszczyk, H; Zgura, I S; Zhalov, M; Zhang, H; Zhang, X; Zhang, Y; Zhao, C; Zhigareva, N; Zhou, D; Zhou, Y; Zhou, Z; Zhu, H; Zhu, J; Zhu, X; Zichichi, A; Zimmermann, A; Zimmermann, M B; Zinovjev, G; Zyzak, M

The measurement of primary [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] production at mid-rapidity ([Formula: see text] 0.5) in proton-proton collisions at [Formula: see text][Formula: see text] 7 TeV performed with a large ion collider experiment at the large hadron collider (LHC) is reported. Particle identification is performed using the specific ionisation energy-loss and time-of-flight information, the ring-imaging Cherenkov technique and the kink-topology identification of weak decays of charged kaons. Transverse momentum spectra are measured from 0.1 up to 3 GeV/[Formula: see text] for pions, from 0.2 up to 6 GeV/[Formula: see text] for kaons and from 0.3 up to 6 GeV/[Formula: see text] for protons. The measured spectra and particle ratios are compared with quantum chromodynamics-inspired models, tuned to reproduce also the earlier measurements performed at the LHC. Furthermore, the integrated particle yields and ratios as well as the average transverse momenta are compared with results at lower collision energies.

Which Way is Up? Lessons Learned from Space Shuttle Sensorimotor Research

Science.gov (United States)

Wood, S. J.; Reschke, M. F.; Harm, D. L.; Paloski, W. H.; Bloomberg, J. J.

2011-01-01

The Space Shuttle Program provided the opportunity to examine sensorimotor adaptation to space flight in unprecedented numbers of astronauts, including many over multiple missions. Space motion sickness (SMS) severity was highly variable across crewmembers. SMS generally lasted 2-3 days in-flight with approximately 1/3 of crewmembers experiencing moderate to severe symptoms, and decreased incidence in repeat flyers. While SMS has proven difficult to predict from susceptibility to terrestrial analogs, symptoms were alleviated by medications, restriction of early activities, maintaining familiar orientation with respect to the visual environment and maintaining contact cues. Adaptive changes were also reflected by the oculomotor and perceptual disturbances experienced early inflight and by the perceptual and motor coordination problems experienced during re-entry and landing. According to crew self-reports, systematic head movements performed during reentry, as long as paced within one's threshold for motion tolerance, facilitated the early readaptation process. The Shuttle provided early postflight crew access to document the initial performance decrements and time course of recovery. These early postflight measurements were critical to inform the program of risks associated with extending the duration of Shuttle missions. Neurological postflight deficits were documented using a standardized subjective rating by flight surgeons. Computerized dynamic posturography was also implemented as a quantitative means of assessing sensorimotor function to support crew return-to-duty assessments. Towards the end of the Shuttle Program, more emphasis has been placed on mapping physiological changes to functional performance. Future commercial flights will benefit from pre-mission training including exposures to launch and entry G transitions and sensorimotor adaptability assessments. While SMS medication usage will continue to be refined, non-pharmacological countermeasures (e

Theoretical study of parity violating asymmetry in proton-proton (pp) scattering

International Nuclear Information System (INIS)

Singh, S.K.; Sajjad Athar, M.; Waris, Atiya

2000-01-01

Measurements of parity violating asymmetries in the pp scattering and proton-nucleus scattering with polarised protons provide a very useful tool to study the interplay of weak and strong interactions between the nucleons and within the nucleus. In order to understand these processes in terms of the conventional nucleon-nucleon interaction models, new experiments at the intermediate energies of 221 and 450 MeV and in the higher energy of multi GeV range are to be carried out

The clinical case for proton beam therapy

International Nuclear Information System (INIS)

Foote, Robert L; Haddock, Michael G; Yan, Elizabeth; Laack, Nadia N; Arndt, Carola A S

2012-01-01

Over the past 20 years, several proton beam treatment programs have been implemented throughout the United States. Increasingly, the number of new programs under development is growing. Proton beam therapy has the potential for improving tumor control and survival through dose escalation. It also has potential for reducing harm to normal organs through dose reduction. However, proton beam therapy is more costly than conventional x-ray therapy. This increased cost may be offset by improved function, improved quality of life, and reduced costs related to treating the late effects of therapy. Clinical research opportunities are abundant to determine which patients will gain the most benefit from proton beam therapy. We review the clinical case for proton beam therapy. Proton beam therapy is a technically advanced and promising form of radiation therapy

On the proton decay

International Nuclear Information System (INIS)

Fonda, L.; Ghirardi, G.C.; Weber, T.

1983-07-01

The problem of the proton decay is considered taking into account that in actual experiments there is an interaction of the proton with its environment which could imply an increase of its theoretical lifetime. It is seen that, by application of the time-energy uncertainty relation, no prolongation of the lifetime is obtained in this case. (author)

Exercise counteracts aging-related memory impairment: a potential role for the astrocytic metabolic shuttle

Directory of Open Access Journals (Sweden)

Sheng-Feng eTsai

2016-03-01

Full Text Available Age-related cognitive impairment has become one of the most common health threats in many countries. The biological substrate of cognition is the interconnection of neurons to form complex information processing networks. Experience-based alterations in the activities of these information processing networks lead to neuroadaptation, which is physically represented at the cellular level as synaptic plasticity. Although synaptic plasticity is known to be affected by aging, the underlying molecular mechanisms are not well described. Astrocytes, a glial cell type that is infrequently investigated in cognitive science, have emerged as energy suppliers which are necessary for meeting the abundant energy demand resulting from glutamatergic synaptic activity. Moreover, the concerted action of an astrocyte-neuron metabolic shuttle is essential for cognitive function; whereas, energetic incoordination between astrocytes and neurons may contribute to cognitive impairment. Whether altered function of the astrocyte-neuron metabolic shuttle links aging to reduced synaptic plasticity is unexplored. However, accumulated evidence documents significant beneficial effects of long-term, regular exercise on cognition and synaptic plasticity. Furthermore, exercise increases the effectiveness of astrocyte-neuron metabolic shuttle by upregulation of astrocytic lactate transporter levels. This review summarizes previous findings related to the neuronal activity-dependent astrocyte-neuron metabolic shuttle. Moreover, we discuss how aging and exercise may shape the astrocyte-neuron metabolic shuttle in cognition-associated brain areas.

DFT studies on proton-ethylene collisions

International Nuclear Information System (INIS)

Wang Zhiping; Zhang Fengshou; Wang Jing

2012-01-01

In the framework of the time-dependent local-density approximation (TDLDA)which applied to valence electrons, coupled non-adiabatically to molecular dynamics of ions, the microscopic mechanisms of collisions between energetic protons and ethylene are studied. Not only the amount of energy lost of the projectile, but also the electron and vibration excitations of the target are identified. In addition, the influences of the collision orientation on the energy loss of the proton and excitation dynamics of ethylene are discussed. It is found that the ionization is enhanced and more electrons are captured by the proton when the proton with the impact energy less than 250 eV moves perpendicularly to the molecular plane. A strong relation between the proton energy lost and the impact orientation is obtained when the impact energy is larger than 250 eV. (authors)

Scattering of intermediate energy protons

International Nuclear Information System (INIS)

Chaumeaux, Alain.

1980-06-01

The scattering of 1 GeV protons appears to be a powerful means of investigating nuclear matter. We worked with SPESI and the formalism of Kerman-Mc Manus and Thaler. The amplitude of nucleon-nucleon scattering was studied as were the aspects of 1 GeV proton scattering (multiple scattering, absorption, spin-orbit coupling, N-N amplitude, KMT-Glauber comparison, second order effects). The results of proton scattering on 16 O, the isotopes of calcium, 58 Ni, 90 Zr and 208 Pb are given [fr

Studies of isolated photons in proton-proton collisions with the EMCAL calorimeter of the ALICE experiment

International Nuclear Information System (INIS)

Ichou, R.

2010-10-01

Prompt photons produced in the hard initial parton-parton scatterings in high-energy proton-proton collisions - such as those at the CERN Large Hadron Collider (LHC) - are an excellent tool to study perturbative Quantum Chromodynamics. In particular, high transverse-momentum (p T ) photons provide crucial information on the parton distribution functions (PDFs) of the proton. Experimentally, in order to measure prompt photons, one needs first to get rid of various other photon sources, especially those from the large background due to π 0 decays. The electromagnetic calorimeter (EMCAL) of the ALICE (A Large Ion Collider Experiment) experiment at the LHC covers the central rapidities and provides improved capabilities to measure high-p T photons in ALICE. We present here studies of photon production in high-energy proton-proton collisions, as well as a complete analysis of their measurement with the EMCAL detector, giving details in particular on the methods developed to separate them from the π 0 decay photons with the help of isolation cuts. (author)

On the model-dependence of the relation between minimum-bias and inelastic proton-proton cross sections

International Nuclear Information System (INIS)

Ostapchenko, S.

2011-01-01

The model-dependence of the relation between the inelastic and various minimum-bias proton-proton cross sections is analyzed, paying a special attention to the sensitivity of minimum-bias triggers to diffractive collisions. Concentrating on the trigger selections of the ATLAS experiment, the measured cross sections are compared to predictions of a number of hadronic Monte Carlo models used in the cosmic ray field. It is demonstrated that the ATLAS results are able to discriminate between different models and between certain theoretical approaches for soft multi-particle production. On the other hand, the strong model-dependence of the selection efficiency of the minimum-bias triggers prevents one from inferring high mass diffraction rate from the discussed data. Moreover, the measured cross sections prove to be insensitive to the production of low mass diffractive states in proton-proton collisions. Consequently, a reliable determination of the total inelastic cross section requires forward proton tracking by a dedicated experiment.

Artificial Neural Network Test Support Development for the Space Shuttle PRCS Thrusters

Science.gov (United States)

Lehr, Mark E.

2005-01-01

A significant anomaly, Fuel Valve Pilot Seal Extrusion, is affecting the Shuttle Primary Reaction Control System (PRCS) Thrusters, and has caused 79 to fail. To help address this problem, a Shuttle PRCS Thruster Process Evaluation Team (TPET) was formed. The White Sands Test Facility (WSTF) and Boeing members of the TPET have identified many discrete valve current trace characteristics that are predictive of the problem. However, these are difficult and time consuming to identify and trend by manual analysis. Based on this exhaustive analysis over months, 22 thrusters previously delivered by the Depot were identified as high risk for flight failures. Although these had only recently been installed, they had to be removed from Shuttles OV103 and OV104 for reprocessing, by directive of the Shuttle Project Office. The resulting impact of the thruster removal, replacement, and valve replacement was significant (months of work and hundreds of thousands of dollars). Much of this could have been saved had the proposed Neural Network (NN) tool described in this paper been in place. In addition to the significant benefits to the Shuttle indicated above, the development and implementation of this type of testing will be the genesis for potential Quality improvements across many areas of WSTF test data analysis and will be shared with other NASA centers. Future tests can be designed to incorporate engineering experience via Artificial Neural Nets (ANN) into depot level acceptance of hardware. Additionally, results were shared with a NASA Engineering and Safety Center (NESC) Super Problem Response Team (SPRT). There was extensive interest voiced among many different personnel from several centers. There are potential spin-offs of this effort that can be directly applied to other data acquisition systems as well as vehicle health management for current and future flight vehicles.