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Sample records for suspicious substances safely

  1. SUSPICIOUS POST

    CERN Multimedia

    Relations with the Host States Service

    2001-01-01

    If you receive a suspicious letter or package in the post, please do not open it and contact the Fire Brigade Tel. 74444. They will contact the CERN Medical Service. This is especially important in today's current situation with regard to the Anthrax scare. For further information, the Permanent Mission of Switzerland to the International Organisations in Geneva recommends the following web sites:   http://www.admin.ch/ch/f/cf/brennpunkt/03.html http://www.who.int/emc-documents/zoonoses/whoemczdi986c.html

  2. Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review.

    Science.gov (United States)

    Soleimani, Vahid; Sahebkar, Amirhossein; Hosseinzadeh, Hossein

    2018-02-26

    Curcumin is the major constituent of turmeric (Curcuma longa). Turmeric has been widely used as a spice in foods and for therapeutic applications such as anti-inflammatory, antihyperlipidemic, and antimicrobial activities. Turmeric and curcumin are nonmutagenic and nongenotoxic. Oral use of turmeric and curcumin did not have reproductive toxicity in animals at certain doses. Studies on human did not show toxic effects, and curcumin was safe at the dose of 6 g/day orally for 4-7 weeks. However, some adverse effects such as gastrointestinal upsets may occur. Moreover, oral bioavailable formulations of curcumin were safe for human at the dose of 500 mg two times in a day for 30 days, but there are still few trials and more studies are needed specially on nanoformulations and it should be discussed in a separate article. In addition, curcumin is known as a generally recognized as safe substance. This review discusses the safety and toxicity of turmeric and curcumin in medicine. Turmeric and curcumin are nontoxic for human especially in oral administration. Turmeric and curcumin are also safe in animals. They are nonmutagenic and are safe in pregnancy in animals but more studies in human are needed. Copyright © 2018 John Wiley & Sons, Ltd.

  3. Code of Practice for the safe transport of radioactive substances 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This Federal Code revises an earlier Code on the same subject issued in 1982 and was formulated under the Environment Protection (Nuclear Codes) Act 1978. The purpose of the Code is to establish uniform safety standards, applicable throughout the Commonwealth of Australia, to provide for the protection of persons and the environment, against any dangers associated with the transport of radioactive substances. The Code uses as a basis the IAEA Regulations for the Safe Transport of Radioactive Materials. This new edition takes into account the 1985 Edition of the Regulations incorporating the 1988 Supplement and provides, furthermore, that radiation protection standards will also be subject to recommendations of the Australian National Health and Medical Research Council [fr

  4. Development of Self-Remediating Packaging for Safe and Secure Transport of Infectious Substances.

    Energy Technology Data Exchange (ETDEWEB)

    Guilinger, Terry Rae; Gaudioso, Jennifer M; Aceto, Donato Gonzalo; Lowe, Kathleen M.; Tucker, Mark D; Salerno, Reynolds Mathewson; Souza, Caroline Ann

    2006-11-01

    As George W. Bush recognized in November 2001, "Infectious diseases make no distinctions among people and recognize no borders." By their very nature, infectious diseases of natural or intentional (bioterrorist) origins are capable of threatening regional health systems and economies. The best mechanism for minimizing the spread and impact of infectious disease is rapid disease detection and diagnosis. For rapid diagnosis to occur, infectious substances (IS) must be transported very quickly to appropriate laboratories, sometimes located across the world. Shipment of IS is problematic since many carriers, concerned about leaking packages, refuse to ship this material. The current packaging does not have any ability to neutralize or kill leaking IS. The technology described here was developed by Sandia National Laboratories to provide a fail-safe packaging system for shipment of IS that will increase the likelihood that critical material can be shipped to appropriate laboratories following a bioterrorism event or the outbreak of an infectious disease. This safe and secure packaging method contains a novel decontaminating material that will kill or neutralize any leaking infectious organisms; this feature will decrease the risk associated with shipping IS, making transport more efficient. 3 DRAFT4

  5. 21 CFR 582.1 - Substances that are generally recognized as safe.

    Science.gov (United States)

    2010-04-01

    ... illustration, the Commissioner regards such common food ingredients as salt, pepper, sugar, vinegar, baking... constitute a finding on the part of the Department that the substance is useful as a supplement to the diet...

  6. Hydrogen fluoride (HF) substance flow analysis for safe and sustainable chemical industry.

    Science.gov (United States)

    Kim, Junbeum; Hwang, Yongwoo; Yoo, Mijin; Chen, Sha; Lee, Ik-Mo

    2017-11-01

    In this study, the chemical substance flow of hydrogen fluoride (hydrofluoric acid, HF) in domestic chemical industries in 2014 was analyzed in order to provide a basic material and information for the establishment of organized management system to ensure safety during HF applications. A total of 44,751 tons of HF was made by four domestic companies (in 2014); import amount was 95,984 tons in 2014 while 21,579 tons of HF was imported in 2005. The export amount of HF was 2180 tons, of which 2074 ton (China, 1422 tons, U.S. 524 tons, and Malaysia, 128 tons) was exported for the manufacturing of semiconductors. Based on the export and import amounts, it can be inferred that HF was used for manufacturing semiconductors. The industries applications of 161,123 tons of HF were as follows: manufacturing of basic inorganic chemical substance (27,937 tons), manufacturing of other chemical products such as detergents (28,208 tons), manufacturing of flat display (24,896 tons), and manufacturing of glass container package (22,002 tons). In this study, an analysis of the chemical substance flow showed that HF was mainly used in the semiconductor industry as well as glass container manufacturing. Combined with other risk management tools and approaches in the chemical industry, the chemical substance flow analysis (CSFA) can be a useful tool and method for assessment and management. The current CSFA results provide useful information for policy making in the chemical industry and national systems. Graphical abstract Hydrogen fluoride chemical substance flows in 2014 in South Korea.

  7. DEET, Active Substance Of Repellent That Effective And Safe For Travelers

    Directory of Open Access Journals (Sweden)

    Made Ika Lestari

    2013-10-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE Increased flow of tourism to the tropics and the changing patterns of vector-borne diseases require increased protection against insects. To prevent transmission of the disease is done several ways that increase self-protection by using mosquito repellent can protect travelers while outdoor activities. One option is active formula mosquito repellent DEET. The purpose of this paper is to determine the best dosage forms for travelers DEET., To determine the effectiveness and safety of DEET and to know the workings of the active ingredient DEET. The method of writing is the literature search through medical journals and articles. From the search was obtained, the most appropriate anti-mosquito travelers to use while on the move outdoors in the dosage form is DEET lotion applied to the skin as the most secure and durable because it does not easily evaporate. Mosquito repellent containing DEET has been proven effective and safe for use in adults, children, and pregnant women, but should still follow the instructions. The workings of the mosquito repellent DEET mosquito dispel is manipulating 1-Octen-3-ol used by mosquitoes to detect human presence. So ORN (olfactory receptor neurons in the mosquitoes can not respond anymore to the maximum, so that people avoid the bites nyamuk. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New

  8. Examination of suspicious objects by virus analysts

    Science.gov (United States)

    Ananin, E. V.; Ananina, I. S.; Nikishova, A. V.

    2018-05-01

    The paper presents data on virus threats urgency. But in order for antiviruses to work properly, all data on new implementations of viruses should be added to its database. For that to be done, all suspicious objects should be investigated. It is a dangerous process and should be done in the virtual system. However, it is not secure for the main system as well. So the diagram of a secure workplace for a virus analyst is proposed. It contains software for its protection. Also all kinds of setting to ensure security of the process of investigating suspicious objects are proposed. The proposed approach allows minimizing risks caused by the virus.

  9. Effect of Educational Program to Encourage Safe Sexual Behaviors Among Addicted Men Refered to Substance Abuse Treatment Centers in Hamadan, Western Iran: Applying the Theory of Planned Behavior

    Directory of Open Access Journals (Sweden)

    Babak Moeini

    2014-06-01

    Full Text Available Introduction: Unsafe sexual behaviors as important risky behaviors can expose individuals and society to dangerous infectious disease such as AIDS and viral hepatitis. Considering the high prevalence of unsafe sexual behaviors, this study aimed to determine the effect of educational programs to encourage safe sexual behaviors among substance abusers referred to substance abuse treatment centers in Hamadan, Western Iran by applying the theory of planned behavior. Materials & Methods: This quasi-experimental study was performed on 104 men substance abusers (52 participants in each of the control and intervention groups referred to substance abuse treatment centers in Hamadan. Data collection tool was a questionnaire containing demographic information and the theory of planned behavior constructs. Before the educational program, questionnaires were completed by both groups. After the pretest in both groups, participants in the intervention group participated in four educational sessions designed based on the theory of planned behavior. Two months after the end of program, posttest was performed. Data was analyzed using independent T-test, chi-square, fisher exact test, McNemar’s test and multiple linear regressions using SPSS-16. Results: After educational intervention, the mean scores of the theory constructs (attitude toward behavior, subjective norms, behavioral control, behavioral intention and behaviors, in the intervention group increased significantly (P<0.05, despite the fact, changes were not significant in the control group. Conclusion: Implementation of educational courses to encourage safe sexual behaviors based on the theory of planned behavior can be beneficial for substance abusers referred to substance abuse treatment centers.

  10. Teaching preschool children to report suspicious packages to adults.

    Science.gov (United States)

    May, Michael E; Shayter, Ashley M; Schmick, Ayla; Barron, Becky; Doherty, Meghan; Johnson, Matthew

    2018-05-16

    Law enforcement agencies stress that public reporting of terror-related crime is the predominant means for disrupting these actions. However, schools may be unprepared because the majority of the populace may not understand the threat of suspicious materials or what to do when they are found on school grounds. The purpose of this study was to systematically teach preschool children to identify and report suspicious packages across three experiments. In the first experiment, we used multiple exemplar training to teach children to identify the characteristics of safe and unsafe packages. In the second experiment, we taught participants to identify the locations where packages should be considered unsafe. Finally, in the third experiment, we used behavioral skills training to teach participants to avoid touching unsafe packages, leave the area where they were located, and report their discovery to an adult. Results suggest the participants quickly developed these skills. Implications for safety skills in young school children are discussed. © 2018 Society for the Experimental Analysis of Behavior.

  11. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Science.gov (United States)

    2010-04-01

    ... of these limited conditions of use, which may include the category of food(s), the technical effect(s... within such limitation(s), including the category of food(s), the functional use(s) of the ingredient... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Substances added directly to human food affirmed as...

  12. 21 CFR 186.1 - Substances added indirectly to human food affirmed as generally recognized as safe (GRAS).

    Science.gov (United States)

    2010-04-01

    ... ingredient, one or more of these limited conditions of use, which may include the category of food-contact...(s), it shall be used in food-contact surfaces only within such limitation(s), including the category... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Substances added indirectly to human food affirmed...

  13. 75 FR 31800 - Substances Generally Recognized as Safe Added to Food for Animals; Notice of Pilot Program

    Science.gov (United States)

    2010-06-04

    ... Cosmetic Act (the act). The 1958 amendment required that, before a new additive could be used in food, its... exemption. FDA has defined ``safe'' as a reasonable certainty in the minds of competent scientists that the... recommendation of an authoritative body such as the National Research Council of the National Academy of Sciences...

  14. A Suspicious Action Detection System Considering Time Series

    Science.gov (United States)

    Kozuka, Noriaki; Kimura, Koji; Hagiwara, Masafumi

    The paper proposes a new system that can detect suspicious actions such as a car break-in and surroundings in an open space parking, based on image processing. The proposed system focuses on three points of “order”, “time”, and “location” of human actions. The proposed system has the following features: it 1) deals time series data flow, 2) estimates human actions and the location, 3) extracts suspicious action detection rules automatically, 4) detects suspicious actions using the suspicious score. We carried out experiments using real image sequences. As a result, we obtained about 7.8% higher estimation rate than the conventional system.

  15. 75 FR 75586 - Confidentiality of Suspicious Activity Reports

    Science.gov (United States)

    2010-12-03

    ...] RIN 1550-AC26 Confidentiality of Suspicious Activity Reports AGENCY: The Office of Thrift Supervision... implementing the Bank Secrecy Act (BSA) governing the confidentiality of a suspicious activity report (SAR) to... corporations regulated by the OTS, to keep certain records and make certain reports that have been determined...

  16. 75 FR 75576 - Confidentiality of Suspicious Activity Reports

    Science.gov (United States)

    2010-12-03

    ...-2010-0019] RIN 1557-AD17 Confidentiality of Suspicious Activity Reports AGENCY: The Office of the... suspicious activity report (SAR) to: clarify the scope of the statutory prohibition on the disclosure by a... institutions, including national banks regulated by the OCC, to keep certain records and make certain reports...

  17. 12 CFR 21.11 - Suspicious Activity Report.

    Science.gov (United States)

    2010-01-01

    ... or a suspicious transaction related to a money laundering activity or a violation of the Bank Secrecy... of suspects. (4) Transactions aggregating $5,000 or more that involve potential money laundering or...

  18. Safe sex

    Science.gov (United States)

    ... sex; Sexually transmitted - safe sex; GC - safe sex; Gonorrhea - safe sex; Herpes - safe sex; HIV - safe sex; ... contact. STIs include: Chlamydia Genital herpes Genital warts Gonorrhea Hepatitis HIV HPV Syphilis STIs are also called ...

  19. Money laundering: correlation between risk assessment and suspicious transactions

    Directory of Open Access Journals (Sweden)

    Sonja Cindori

    2013-06-01

    Full Text Available The risk assessment system was introduced in the Republic of Croatia in 2009, as a result of harmonization with international standards, especially the Directive 2005/60/EC on the prevention of the use of the financial system for the purpose of money laundering and terrorist financing. Risk assessment is an extensive concept which requires not only a legislative framework, but also the application of numerous criteria for its effective implementation in practice. Among these criteria are suspicious transactions, closely related to the assessment of the customer, transaction, product or service.The undeniable contribution of suspicious transactions to the quality of the risk assessment system will be confirmed by a statistical analysis of a number of West and East European countries. A combination of strict, but sufficiently flexible legal provisions governing the system for prevention of money laundering and terrorist financing and a statistical analysis of reported suspicious transactions will lead to conclusions that either support or represent criticism of the efficiency of application of the risk assessment system in practice.The aforementioned statistical analysis will show whether suspicious transactions are a reliable criterion for the risk assessment analysis, and whether they can be considered the only such criterion. There is a possibility that the findings of the analysis will be contradictory to those of some international studies.

  20. Upright stereotactic vacuum-assisted needle biopsy of suspicious breast microcalcification

    International Nuclear Information System (INIS)

    Sim, L. S. J.; Kei, P. L.

    2008-01-01

    Full text: Stereotactic core needle biopsy is a useful technique for evaluation of suspicious breast microcalcifications. Thf development of the 11-G vacuum-assisted biopsy system offers another method of minimally invasive biopsy carried out on a conventional mammography unit. We evaluate its usefulness, efficacy and safety in Asian women.. Vacuum-assisted biopsy was carried out through the lateral approach using an add-on stereotactic device attached to a mammography unit. One hundred and five lesions were sampled in 97 patients. Excisional biopsy was subsequently Carried out for diagnosis of atypical ductal hyperplasia or carcinoma in high-risk patients. Patients with benign diagnosis underwent mammographic follow up. The technical success rate was 97%. An average of 13.5 tissue cores were retrieved for each lesion. The histopathological result obtained from mammotome was benign in 84.8% and malignant in 15.2%. The benign microcalcifications were predominantly fibrocystic change (n = 42)| whereas the malignant microcalcifications included ductal carcinoma in situ (n = 15) and invasive carcinoma (n = 1). Twenty-two patients underwent subsequent open surgical biopsy but no underestimation of disease was seen. Only two patients had vasovagal syncope and three others felt unwell during the biopsy. Nine patients had small haema-1 tomas, which resolved spontaneously. Vacuum-assisted biopsy carried out on an upright stereotactic mammography] unit is a safe and effective method for evaluation of suspicious microcalcifications.

  1. Neural Correlates of Suspiciousness and Interactions with Anxiety during Emotional and Neutral Word Processing

    Directory of Open Access Journals (Sweden)

    Joscelyn E Fisher

    2014-06-01

    Full Text Available Suspiciousness is usually classified as a symptom of psychosis, but it also occurs in depression and anxiety disorders. Though how suspiciousness overlaps with depression is not obvious, suspiciousness does seem to overlap with anxious apprehension and anxious arousal (e.g., verbal iterative processes and vigilance about environmental threat. However, suspiciousness also has unique characteristics (e.g., concern about harm from others and vigilance about social threat. Given that both anxiety and suspiciousness have been associated with abnormalities in emotion processing, it is unclear whether it is the unique characteristics of suspiciousness or the overlap with anxiety that drive abnormalities in emotion processing.. Event-related brain potentials were obtained during an emotion-word Stroop task. Results indicated that suspiciousness interacts with anxious apprehension to modulate initial stimulus perception processes. Suspiciousness is associated with attention to all stimuli regardless of emotion content. In contrast, anxious arousal is associated with a later response to emotion stimuli only. These results suggest that suspiciousness and anxious apprehension share overlapping processes, but suspiciousness alone is associated with a hyperactive early vigilance response. Depression did not interact with suspiciousness to predict response to emotion stimuli. These findings suggest that it may be informative to assess suspiciousness in conjunction with anxiety in order to better understand how these symptoms interact and contribute to dysfunctional emotion processing.

  2. Schizotypy and mindfulness: Magical thinking without suspiciousness characterizes mindfulness meditators

    Directory of Open Access Journals (Sweden)

    Elena Antonova

    2016-09-01

    Full Text Available Despite growing evidence for demonstrated efficacy of mindfulness in various disorders, there is a continuous concern about the relationship between mindfulness practice and psychosis. As schizotypy is part of the psychosis spectrum, we examined the relationship between long-term mindfulness practice and schizotypy in two independent studies. Study 1 included 24 experienced mindfulness practitioners (19 males from the Buddhist tradition (meditators and 24 meditation-naïve individuals (all males. Study 2 consisted of 28 meditators and 28 meditation-naïve individuals (all males. All participants completed the Schizotypal Personality Questionnaire (Raine, 1991, a self-report scale containing 9 subscales (ideas of reference, excessive social anxiety, magical thinking, unusual perceptual experiences, odd/eccentric behavior, no close friends, odd speech, constricted affect, suspiciousness. Participants of study 2 also completed the Five-Facet Mindfulness Questionnaire which assesses observing (Observe, describing (Describe, acting with awareness (Awareness, non-judging of (Non-judgment and non-reactivity to inner experience (Non-reactivity facets of trait mindfulness. In both studies, meditators scored significantly lower on suspiciousness and higher on magical thinking compared to meditation-naïve individuals and showed a trend towards lower scores on excessive social anxiety. Excessive social anxiety correlated negatively with Awareness and Non-judgment; and suspiciousness with Awareness, Non-judgment and Non-reactivity facets across both groups. The two groups did not differ in their total schizotypy score. We conclude that mindfulness practice is not associated with an overall increase in schizotypal traits. Instead, the pattern suggests that mindfulness meditation, particularly with an emphasis on the Awareness, Non-judgment and Non-reactivity aspects, may help to reduce suspiciousness and excessive social anxiety.

  3. About possibility of creation of ecologically pure, safe nuclear power plants on the basis of high-effective resonant neutron interaction with splitting substances

    International Nuclear Information System (INIS)

    Irdyncheyev, L.A.; Malofeyev, A.M.; Frid, E.S.; Abramov, E.P.

    1993-01-01

    Currently the most important problem in nuclear engineering is creation of ecologically pure, safe nuclear power plants in the context of real danger of global ecological pollution of the environment with long-lived fission products and the resultant transuranium nuclides. The problem can be solved by creating nuclear power plants on the basis of high-effective resonant interaction (HERI). Such power plants would provide the total cycle, including nuclear fuel production (Plutonium-239 from Uranium-238), combustion and waste products salvaging by way of transformation of radioactive nuclides into stable isotopes

  4. How safe is safe?

    International Nuclear Information System (INIS)

    Hughes, C.F.; Flood, M.

    1996-01-01

    60 and 70 degree convexo-concave valve. Nine hundred and one valves were implanted in Australia. Twelve strut fractures were reported. Two other patients have been explanted and have demonstrated 'single leg separation'. This particular problem was only investigated when two patients died of a fractured valve in the same hospital on the same day. A retrospective study of all known patients in Australia has shown poor follow up, lack of knowledge and indeed lack of interest in device failure modes. Consequently, the Australian and New Zealand Heart Valve Registry was established to track all implanted valves and to notify physicians of any new information. This is perhaps the first device-specific register in Australia. The safety of individual devices is often not known by manufacturers, regulators and clinicians alike. No follow up is available and large volume long term studies are yet to be implemented for the majority of devices. Without such studies and without mandatory problem reporting, the relative safety of medical devices will continue to be measured by banner headlines, sensational TV 'grabs' and protracted law suits. At present, only schemes such as the Problem Reporting Scheme can tell us (albeit vaguely) 'how safe is safe'

  5. Formulation of attractive toxic sugar bait (ATSB) with safe EPA-exempt substance significantly diminishes the Anopheles sergentii population in a desert oasis.

    Science.gov (United States)

    Revay, Edita E; Schlein, Yosef; Tsabari, Onie; Kravchenko, Vasiliy; Qualls, Whitney; De-Xue, Rui; Beier, John C; Traore, Sekou F; Doumbia, Seydou; Hausmann, Axel; Müller, Günter C

    2015-10-01

    Attractive toxic sugar bait (ATSB) is a highly effective method which targets mosquitoes based on their sugar foraging behavior, by presenting baits of attractive compounds in combination with sugar and oral toxin to local mosquito populations. Environmental concerns and insecticide selection-pressure have prompted investigations of novel, ecologically-harmless substances which can be used as insecticides. This study examined the efficacy of microencapsulated garlic-oil as the oral toxin component of ATSB for controlling Anopheles sergentii populations inhabiting desert-surrounded wetlands in Israel. ATSB solution containing 0.4% encapsulated garlic oil was applied to local vegetation around a streamlet located in the lower Jordan Valley. To determine the propensity of bait ingestion, and assess the potential ecological impact of the method, mosquito and non-target specimens were collected and tested for the presence of natural plant- or attractive sugar bait (ASB)-derived sugars. Over the experimental period, biting-pressure values in the ATSB treatment site decreased by 97.5%, while at the control site, treated with non-toxic ASB, no significant changes were observed. Approximately 70% of the mosquitoes collected before both treatments, as well as those captured following the application of ASB at the control site, were found to have ingested sugar prior to capture. Non-target insects were minimally affected by the treatment when ATSB was applied to foliage of non-flowering plants. Of the non-Diptera species, only 0.7% of the sampled non-target insects were found to have ingested ASB-solution which was applied to green vegetation, compared with 8.5% which have foraged on ASB-derived sugars applied to flowering plants. Conversely, a high proportion of the non-target species belonging to the order Diptera, especially non-biting midges, were found to have ingested foliage-applied ASB, with more than 36% of the specimens collected determined to have foraged on bait

  6. 76 FR 69204 - Anti-Money Laundering Program and Suspicious Activity Reporting Requirements for Housing...

    Science.gov (United States)

    2011-11-08

    ... 1506-AB14 Anti-Money Laundering Program and Suspicious Activity Reporting Requirements for Housing... enterprises as financial institutions for the purpose of requiring them to establish anti-money laundering... organizations to establish anti-money laundering programs and report suspicious activities is intended to help...

  7. 31 CFR 103.21 - Reports by casinos of suspicious transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Reports by casinos of suspicious....21 Reports by casinos of suspicious transactions. (a) General. (1) Every casino shall file with Fin... relevant to a possible violation of law or regulation. A casino may also file with FinCEN, by using the...

  8. Sonographic findings of thyroid cancer initially assessed as no suspicious malignancy

    International Nuclear Information System (INIS)

    Kim, Do Youn; Kang, Seok Seon; Ji, Eun Kyung; Kwon, Tae Hee; Park, Hae Lin; Shim, Jeong Yun

    2008-01-01

    To review the retrospective imaging findings of thyroid cancer initially assessed as no suspicious malignancy. Of 338 nodules confirmed to be thyroid cancer, this study included 38 patients with 39 nodules assessed as no suspicious malignancy on initial sonography. (mean age:39 years, 36 females and 2 males). We evaluated sonographic findings by shape, margin, echogenecity, calcification, cystic degeneration and peripheral hypoechoic rim retrospectively. We analyzed whether sonographic findings were different according to the size (standard:1 cm). The most frequent sonographic findings were avoid to round shape 90%, well-defined smooth margin 64%, hypoechogenecity 54%, no calcification 92%, no cystic degeneration 77% and peripheral hypoechoic rim 56%. Suspicious malignancy findings were taller than wide shape 10%, well-defined spiculated margin 36%, markedly hypoechogenecity 10% and microcalcifications 8%. Isoechogenecity, cystic degeneration and peripheral hypoechoic rim were common in 1 cm more than nodules. Well-defined spiculated margin was common in 1 cm less than nodules. In retrospective, 56% showed no suspicious malignancy finding. Although nodules assessed as no suspicious malignancy on initial US had many retrospectively suspicious malignancy findings, still many nodules showed no suspicious malignancy finding. Suspicious findings were ignored due to equivocal finding in small size, isoechogenecity, cystic degeneration or peripheral hypoechoic rim. We need careful observation

  9. Minimising bias in the forensic evaluation of suspicious paediatric injury.

    Science.gov (United States)

    Skellern, Catherine

    2015-08-01

    In the rules of evidence in all legal jurisdictions, medical experts are required to maintain objectivity when providing opinions. When interpreting medical evidence, doctors must recognise, acknowledge and manage uncertainties to ensure their evidence is reliable to legal decision-makers. Even in the forensic sciences such as DNA analysis, implicit bias has been shown to influence how results are interpreted from cognitive and contextual biases unconsciously operating. In cases involving allegations of child abuse there has been significant exposure in the media, popular magazines, legal journals and in the published medical literature debating the reliability of medical evidence given in these proceedings. In these cases judges have historically been critical of experts they perceived had sacrificed objectivity for advocacy by having an investment in a 'side'. This paper firstly discusses the issue of bias then describes types of cognitive biases identified from psychological research applied to forensic evidence including adversarial bias, context bias, confirmation bias and explains how terminology can influence the communication of opinion. It follows with previously published guidelines of how to reduce the risk of bias compromising objectivity in forensic practices then concludes with my own recommendations of practices that can be used by child protection paediatricians and within an organisation when conducting forensic evaluations of suspicious childhood injury to improve objectivity in formulation of opinion evidence. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  10. SAFE Newsletter

    OpenAIRE

    2013-01-01

    The Center of Excellence SAFE – “Sustainable Architecture for Finance in Europe” – is a cooperation of the Center for Financial Studies and Goethe University Frankfurt. It is funded by the LOEWE initiative of the State of Hessen (Landes-Offensive zur Entwicklung wissenschaftlich-ökonomischer Exzellenz). SAFE brings together more than 40 professors and just as many junior researchers who are all dedicated to conducting research in support of a sustainable financial architecture. The Center has...

  11. Suspiciousness and low self-esteem as predictors of misattributions of anger in schizophrenia spectrum disorders.

    Science.gov (United States)

    Lysaker, Paul Henry; Davis, Louanne Whitman; Tsai, Jack

    2009-04-30

    While it is widely recognized that many with schizophrenia have significant difficulties in correctly identifying the emotions of others, less is known about the causes and correlates of particular forms of misattribution, including mistakenly seeing anger in others. One possibility is that persons with high levels of suspiciousness and low levels of self-esteem are at risk to attribute their poor feelings about themselves to the malice of others. To explore this possibility, we identified 52 persons with a schizophrenia spectrum disorder who made significant numbers of errors on the Bell-Lysaker Emotional Recognition Test. We then performed a cluster analysis based on measures of suspiciousness from the Positive and Negative Syndrome Scale and self-esteem from the Rosenberg Self-Esteem Schedule, and found the following four groups: a) High Suspiciousness/High Self-Esteem; b) Mild Suspiciousness/High Self-Esteem; c) High Suspiciousness/Low Self-Esteem; and d) Minimal Suspiciousness/Low Self-Esteem. Comparisons between groups revealed that as predicted the High Suspiciousness/Low Self-Esteem group made significantly more misattributions of anger than other groups, even when levels of depression were controlled for statistically. Implications for addressing the misattributions of anger in schizophrenia are discussed.

  12. Safe Haven.

    Science.gov (United States)

    Bush, Gail

    2003-01-01

    Discusses school libraries as safe havens for teenagers and considers elements that foster that atmosphere, including the physical environment, lack of judgments, familiarity, leisure, and a welcoming nature. Focuses on the importance of relationships, and taking the time to listen to teens and encourage them. (LRW)

  13. Event-related potential correlates of suspicious thoughts in individuals with schizotypal personality features.

    Science.gov (United States)

    Li, Xue-bing; Huang, Jia; Cheung, Eric F C; Gong, Qi-yong; Chan, Raymond C K

    2011-01-01

    Suspiciousness is a common feature of schizophrenia. However, suspicious thoughts are also commonly experienced by the general population. This study aimed to examine the underlying neural mechanism of suspicious thoughts in individuals with and without schizotypal personality disorder (SPD)-proneness, using an event-related potential (ERP) paradigm. Electroencephalography (EEG) was recorded when the "feeling of being seen through" was evoked in the participants. The findings showed a prominent positive deflection of the difference wave within the time window 250-400 ms after stimuli presentation in both SPD-prone and non-SPD-prone groups. Furthermore, the P3 amplitude was significantly reduced in the SPD-prone group compared to the non-SPD-prone group. The current density analysis also indicated hypoactivity in both frontal and temporal regions in the SPD-prone group, suggesting that the frontotemporal cortical network may play a role in the onset of suspicious thoughts. The P3 of difference wave was inversely correlated with the cognitive-perception factor and the suspiciousness/paranoid ideation trait, which provided preliminary electrophysiological evidence for the association of suspiciousness with SPD features.

  14. Safe Grid

    Science.gov (United States)

    Chow, Edward T.; Stewart, Helen; Korsmeyer, David (Technical Monitor)

    2003-01-01

    The biggest users of GRID technologies came from the science and technology communities. These consist of government, industry and academia (national and international). The NASA GRID is moving into a higher technology readiness level (TRL) today; and as a joint effort among these leaders within government, academia, and industry, the NASA GRID plans to extend availability to enable scientists and engineers across these geographical boundaries collaborate to solve important problems facing the world in the 21 st century. In order to enable NASA programs and missions to use IPG resources for program and mission design, the IPG capabilities needs to be accessible from inside the NASA center networks. However, because different NASA centers maintain different security domains, the GRID penetration across different firewalls is a concern for center security people. This is the reason why some IPG resources are been separated from the NASA center network. Also, because of the center network security and ITAR concerns, the NASA IPG resource owner may not have full control over who can access remotely from outside the NASA center. In order to obtain organizational approval for secured remote access, the IPG infrastructure needs to be adapted to work with the NASA business process. Improvements need to be made before the IPG can be used for NASA program and mission development. The Secured Advanced Federated Environment (SAFE) technology is designed to provide federated security across NASA center and NASA partner's security domains. Instead of one giant center firewall which can be difficult to modify for different GRID applications, the SAFE "micro security domain" provide large number of professionally managed "micro firewalls" that can allow NASA centers to accept remote IPG access without the worry of damaging other center resources. The SAFE policy-driven capability-based federated security mechanism can enable joint organizational and resource owner approved remote

  15. [Identification and management of intra-operative suspicious tissues in 20 transsphenoidal surgery cases].

    Science.gov (United States)

    Liu, Jun-Feng; Ke, Chang-Shu; Chen, Xi; Xu, Yu; Zhang, Hua-Qiu; Chen, Juan; Gan, Chao; Li, Chao-Xi; Lei, Ting

    2013-05-01

    To determine appropriate protocols for the identification and management of intra operative suspicious tissues during transsphenoidal surgery. Clinical data and pathological reports of 20 patients with intra-operative suspicious tissues during transsphenoidal surgeries were analyzed retrospectively. The methods for discriminating between adenoma and normal pituitary tissues were reviewed. The postoperative pathological reports revealed that adenoma and normal pituitary tissues coexisted in 9 samples, while 5 samples were identified as normal pituitary tissues, 2 as adenoma tissues, and 4 as other tissues. Adenomas were distinguished from normal pituitary tissues on the basis of intra-operative appearance, texture, blood supply and possible existence of boundary. If decisions are difficult to made during surgeries from the appearance of the suspicious tissues, pathological examinations are advised as a guidance for the next steps.

  16. Computer aided detection of suspicious regions on digital mammograms : rapid segmentation and feature extraction

    Energy Technology Data Exchange (ETDEWEB)

    Ruggiero, C; Giacomini, M; Sacile, R [DIST - Department of Communication Computer and System Sciences, University of Genova, Via Opera Pia 13, 16145 Genova (Italy); Rosselli Del Turco, M [Centro per lo studio e la prevenzione oncologica, Firenze (Italy)

    1999-12-31

    A method is presented for rapid detection of suspicious regions which consists of two steps. The first step is segmentation based on texture analysis consisting of : histogram equalization, Laws filtering for texture analysis, Gaussian blur and median filtering to enhance differences between tissues in different respects, histogram thresholding to obtain a binary image, logical masking in order to detect regions to be discarded from the analysis, edge detection. This method has been tested on 60 images, obtaining 93% successful detection of suspicious regions. (authors) 4 refs, 9 figs, 1 tabs.

  17. Safe cycling!

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    The HSE Unit will be running a cycling safety campaign at the entrances to CERN's restaurants on 14, 15 and 16 May. Pop along to see if they can persuade you to get back in the saddle!   With summer on its way, you might feel like getting your bike out of winter storage. Well, the HSE Unit has come up with some original ideas to remind you of some of the most basic safety rules. This year, the prevention campaign will be focussing on three themes: "Cyclists and their equipment", "The bicycle on the road", and "Other road users". This is an opportunity to think about the condition of your bike as well as how you ride it. From 14 to 16 May, representatives of the Swiss Office of Accident Prevention and the Touring Club Suisse will join members of the HSE Unit at the entrances to CERN's restaurants to give you advice on safe cycling (see box). They will also be organising three activity stands where you can test your knowle...

  18. Toxic substances alert program

    Science.gov (United States)

    Junod, T. L.

    1978-01-01

    A toxicity profile is provided, of 187 toxic substances procured by NASA Lewis Research Center during a 3 1/2 year period, including 27 known or suspected carcinogens. The goal of the program is to assure that the center's health and safety personnel are aware of the procurement and use of toxic substances and to alert and inform the users of these materials as to the toxic characteristics and the control measures needed to ensure their safe use. The program also provides a continuing record of the toxic substances procured, who procured them, what other toxic substances the user has obtained in the past, and where similar materials have been used elsewhere at the center.

  19. 31 CFR 103.18 - Reports by banks of suspicious transactions.

    Science.gov (United States)

    2010-07-01

    ... violations that require immediate attention, such as, for example, ongoing money laundering schemes, the bank... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Reports by banks of suspicious transactions. 103.18 Section 103.18 Money and Finance: Treasury Regulations Relating to Money and Finance...

  20. 31 CFR 103.15 - Reports by mutual funds of suspicious transactions.

    Science.gov (United States)

    2010-07-01

    ... suspected terrorist financing or ongoing money laundering schemes, a mutual fund shall immediately notify by... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Reports by mutual funds of suspicious transactions. 103.15 Section 103.15 Money and Finance: Treasury Regulations Relating to Money and Finance...

  1. 31 CFR 103.20 - Reports by money services businesses of suspicious transactions.

    Science.gov (United States)

    2010-07-01

    ... immediate attention, such as ongoing money laundering schemes, the money services business shall immediately... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Reports by money services businesses of suspicious transactions. 103.20 Section 103.20 Money and Finance: Treasury Regulations Relating to...

  2. 75 FR 76677 - Financial Crimes Enforcement Network: Anti-Money Laundering Program and Suspicious Activity...

    Science.gov (United States)

    2010-12-09

    ...: Anti-Money Laundering Program and Suspicious Activity Report Filing Requirements for Residential... loan or finance companies for the purpose of requiring them to establish anti-money laundering programs...-money laundering program requirements on financial institutions.\\3\\ The authority of the Secretary to...

  3. 75 FR 75593 - Financial Crimes Enforcement Network; Confidentiality of Suspicious Activity Reports

    Science.gov (United States)

    2010-12-03

    ... continuing effort to increase the efficiency and effectiveness of its anti-money laundering and counter... law or regulation, or a suspicious activity related to money laundering, terrorist financing, or other...). \\3\\ The Annunzio-Wylie Anti-Money Laundering Act of 1992 (the Annunzio-Wylie Act), amended the BSA...

  4. 77 FR 8148 - Anti-Money Laundering Program and Suspicious Activity Report Filing Requirements for Residential...

    Science.gov (United States)

    2012-02-14

    ... 1506-AB02 Anti-Money Laundering Program and Suspicious Activity Report Filing Requirements for... finance companies for the purpose of requiring them to establish anti-money laundering programs and report... Secretary is authorized to impose anti-money laundering (``AML'') program requirements on financial...

  5. Automatic detection of suspicious behavior of pickpockets with track-based features in a shopping mall

    NARCIS (Netherlands)

    Bouma, H.; Baan, J.; Burghouts, G.J.; Eendebak, P.T.; Huis, J.R. van; Dijk, J.; Rest, J.H.C. van

    2014-01-01

    Proactive detection of incidents is required to decrease the cost of security incidents. This paper focusses on the automatic early detection of suspicious behavior of pickpockets with track-based features in a crowded shopping mall. Our method consists of several steps: pedestrian tracking, feature

  6. Clinical experiences with photoacoustic breast imaging: the appearance of suspicious lesions

    NARCIS (Netherlands)

    Heijblom, M.

    2014-01-01

    This thesis describes photoacoustic (PA) imaging of suspicious breast lesions. In PA imaging, the tissue of interest is illuminated by short pulses of laser light, usually in the near infrared (NIR) regime. Upon absorption by primarily the tumor vasculature, the light causes a small temperature

  7. 31 CFR 103.19 - Reports by brokers or dealers in securities of suspicious transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Reports by brokers or dealers in... Reports Required To Be Made § 103.19 Reports by brokers or dealers in securities of suspicious transactions. (a) General. (1) Every broker or dealer in securities within the United States (for purposes of...

  8. 31 CFR 103.17 - Reports by futures commission merchants and introducing brokers in commodities of suspicious...

    Science.gov (United States)

    2010-07-01

    ... merchants and introducing brokers in commodities of suspicious transactions. 103.17 Section 103.17 Money and... merchants and introducing brokers in commodities of suspicious transactions. (a) General—(1) Every futures commission merchant (“FCM”) and introducing broker in commodities (“IB-C”) within the United States shall...

  9. How safe is safe enough?

    International Nuclear Information System (INIS)

    Desnoyers, B.; Chanzy, Y.

    2004-01-01

    The IAEA Regulations for the Safe Transport of Radioactive Material, were historically established with the objective to reduce the probability that persons be exposed to unacceptable doses due to normal operation or accident situations during transport of radioactive material. Based on the International Basic Safety Standards for Protection against Ionizing Radiation (BSS), the definition, which was adopted for an unacceptable dose for an accident situation, is the excess of the maximum dose limits permissible in a single year for the occupational exposure of a worker in the BSS. Concerning the severity of accident situations, it has always be clearly stated that the objective of the tests for demonstrating ability to withstand accident conditions of transport was not to cover every accident condition, but solely most of them. The last available evaluations regarding the rate of accidents which are covered by the standardised accident conditions of transport defined in the IAEA Regulations give a range of about 80%, plus or minus 15% which depends on transport mode and studies. Consequently, slight variations in the capabilities of the packages to meet the specified performance would probably not have significant consequences on the protection level in case of accident. In the assessment of the compliance with the regulations, the tendency of experts, taking advantage of the enhanced performances of computer calculation codes, is to ask more and more calculations, with more and more accuracy, leading to more and more restrictions. Consequently, cost and delay are considerably increased without any evidence of an equivalent effect on the level of protection. This paper will initiate a reflection on the general objectives and principles when implementing the Regulations, in such a way that demonstrations remain cost effective, taking into account evolution of the techniques and a high level of safety

  10. Substance use - prescription drugs

    Science.gov (United States)

    Substance use disorder - prescription drugs; Substance abuse - prescription drugs; Drug abuse - prescription drugs; Drug use - prescription drugs; Narcotics - substance use; Opioid - substance use; Sedative - substance ...

  11. Suspicious Behavior Detection System for an Open Space Parking Based on Recognition of Human Elemental Actions

    Science.gov (United States)

    Inomata, Teppei; Kimura, Kouji; Hagiwara, Masafumi

    Studies for video surveillance applications for preventing various crimes such as stealing and violence have become a hot topic. This paper proposes a new video surveillance system that can detect suspicious behaviors such as a car break-in and vandalization in an open space parking, and that is based on image processing. The proposed system has the following features: it 1)deals time series data flow, 2)recognizes “human elemental actions” using statistic features, and 3)detects suspicious behavior using Subspace method and AdaBoost. We conducted the experiments to test the performance of the proposed system using open space parking scenes. As a result, we obtained about 10.0% for false positive rate, and about 4.6% for false negative rate.

  12. Suspicious amorphous microcalcifications detected on full-field digital mammography: correlation with histopathology

    Directory of Open Access Journals (Sweden)

    Vera Christina Camargo de Siqueira Ferreira

    2018-03-01

    Full Text Available Abstract Objective: To evaluate suspicious amorphous calcifications diagnosed on full-field digital mammography (FFDM and establish correlations with histopathology findings. Materials and Methods: This was a retrospective study of 78 suspicious amorphous calcifications (all classified as BI-RADS® 4 detected on FFDM. Vacuum-assisted breast biopsy (VABB was performed. The histopathological classification of VABB core samples was as follows: pB2 (benign; pB3 (uncertain malignant potential; pB4 (suspicion of malignancy; and pB5 (malignant. Treatment was recommended for pB5 lesions. To rule out malignancy, surgical excision was recommended for pB3 and pB4 lesions. Patients not submitted to surgery were followed for at least 6 months. Results: Among the 78 amorphous calcifications evaluated, the histopathological analysis indicated that 8 (10.3% were malignant/suspicious (6 classified as pB5 and 2 classified as pB4 and 36 (46.2% were benign (classified as pB2. The remaining 34 lesions (43.6% were classified as pB3: 33.3% were precursor lesions (atypical ductal hyperplasia, lobular neoplasia, or flat epithelial atypia and 10.3% were high-risk lesions. For the pB3 lesions, the underestimation rate was zero. Conclusion: The diagnosis of precursor lesions (excluding atypical ductal hyperplasia, which can be pB4 depending on the severity and extent of the lesion should not necessarily be considered indicative of underestimation of malignancy. Suspicious amorphous calcifications correlated more often with precursor lesions than with malignant lesions, at a ratio of 3:1.

  13. Flow detection via sparse frame analysis for suspicious event recognition in infrared imagery

    Science.gov (United States)

    Fernandes, Henrique C.; Batista, Marcos A.; Barcelos, Celia A. Z.; Maldague, Xavier P. V.

    2013-05-01

    It is becoming increasingly evident that intelligent systems are very bene¯cial for society and that the further development of such systems is necessary to continue to improve society's quality of life. One area that has drawn the attention of recent research is the development of automatic surveillance systems. In our work we outline a system capable of monitoring an uncontrolled area (an outside parking lot) using infrared imagery and recognizing suspicious events in this area. The ¯rst step is to identify moving objects and segment them from the scene's background. Our approach is based on a dynamic background-subtraction technique which robustly adapts detection to illumination changes. It is analyzed only regions where movement is occurring, ignoring in°uence of pixels from regions where there is no movement, to segment moving objects. Regions where movement is occurring are identi¯ed using °ow detection via sparse frame analysis. During the tracking process the objects are classi¯ed into two categories: Persons and Vehicles, based on features such as size and velocity. The last step is to recognize suspicious events that may occur in the scene. Since the objects are correctly segmented and classi¯ed it is possible to identify those events using features such as velocity and time spent motionless in one spot. In this paper we recognize the suspicious event suspicion of object(s) theft from inside a parked vehicle at spot X by a person" and results show that the use of °ow detection increases the recognition of this suspicious event from 78:57% to 92:85%.

  14. Suspiciousness perception in dynamic scenes: a comparison of CCTV operators and novices.

    Directory of Open Access Journals (Sweden)

    Christina Jayne Howard

    2013-08-01

    Full Text Available Perception of scenes has typically been investigated by using static or simplified visual displays. How attention is used to perceive and evaluate dynamic, realistic scenes is more poorly understood, in part due to the problem of comparing eye fixations to moving stimuli across observers. When the task and stimulus is common across observers, consistent fixation location can indicate that that region has high goal-based relevance. Here we investigated these issues when an observer has a specific, and naturalistic, task: closed-circuit television (CCTV monitoring. We concurrently recorded eye movements and ratings of perceived suspiciousness as different observers watched the same set of clips from real CCTV footage. Trained CCTV operators showed a greater consistency in fixation location and greater consistency in suspiciousness judgements than untrained observers. Training appears to increase between-operators consistency by learning 'knowing what to look for' in these scenes. We used a novel ‘Dynamic Area of Focus (DAF’ analysis to show that in CCTV monitoring there is a temporal relationship between eye movements and subsequent manual responses, as we have previously found for a sports video watching task. For trained CCTV operators and for untrained observers, manual responses were most highly related to between-observer eye position spread when a temporal lag was introduced between the fixation and response data. Shortly after between-observer eye positions became most similar, observers tended to push the joystick to indicate perceived suspiciousness. Conversely, shortly after between-observer eye positions became dissimilar, observers tended to rate suspiciousness as low. These data provide further support for this DAF method as an important tool for examining goal-directed fixation behaviour when the stimulus is a real moving image.

  15. Automatic detection of suspicious behavior of pickpockets with track-based features in a shopping mall

    OpenAIRE

    Bouma, H.; Baan, J.; Burghouts, G.J.; Eendebak, P.T.; Huis, J.R. van; Dijk, J.; Rest, J.H.C. van

    2014-01-01

    Proactive detection of incidents is required to decrease the cost of security incidents. This paper focusses on the automatic early detection of suspicious behavior of pickpockets with track-based features in a crowded shopping mall. Our method consists of several steps: pedestrian tracking, feature computation and pickpocket recognition. This is challenging because the environment is crowded, people move freely through areas which cannot be covered by a single camera, because the actual snat...

  16. Utilizing Social Media to Further the Nationwide Suspicious Activity Reporting Initiative

    Science.gov (United States)

    2012-09-01

    Initiative NYPD New York Police Department OSINT Open Source Intelligence P2P Peer to Patent SAR Suspicious Activity Report SMS Short Message (or...Media as an Open-Source Intelligence Tool Several government documents outline the use of social media as an Open Source intelligence tool ( OSINT ...social media to be an OSINT tool that federal, state, and local law enforcement agencies should use to develop timely, relevant, and actionable

  17. Surgical resection of highly suspicious pulmonary nodules without a tissue diagnosis

    International Nuclear Information System (INIS)

    Heo, Eun-Young; Lee, Kyung-Won; Jheon, Sanghoon; Lee, Jae-Ho; Lee, Choon-Taek; Yoon, Ho-II

    2011-01-01

    The safety and efficacy of surgical resection of lung nodule without tissue diagnosis is controversial. We evaluated direct surgical resection of highly suspicious pulmonary nodules and the clinical and radiological predictors of malignancy. Retrospective analyses were performed on 113 patients who underwent surgical resection without prior tissue diagnosis for highly suspicious pulmonary nodules. Clinical and radiological characteristics were compared between histologically proven benign and malignant nodules after resection. Total costs, length of hospitalization and waiting time to surgery were compared with those of patients who had tissue diagnosis prior to surgery. Among 280 patients with pulmonary nodules suspicious for lung cancer, 113 (40.4%) underwent operation without prior tissue diagnosis. Lung nodules were diagnosed as malignant in 96 (85%) of the 113 patients. Except for forced expiratory volume in 1 s, clinical characteristics were not significantly different according to the pathologic results. Forty-five (90%) of 50 patients with ground-glass opacity nodules had a malignancy. Mixed ground-glass opacity, bubble lucency, irregular margin and larger size correlated with malignancy in ground-glass opacity nodules (P<0.05). Fifty-one (81%) of 67 patients with solid nodules had a malignancy. Spiculation, pre-contrast attenuation and contrast enhancement significantly correlated with malignancy in solid nodules (P<0.05). Surgical resection without tissue diagnosis significantly decreased total costs, hospital stay and waiting time (P<0.05). Direct surgical resection of highly suspicious pulmonary nodules can be a valid procedure. However, careful patient selection and further investigations are required to justify direct surgical resection. (author)

  18. Role of percent tissue altered on ectasia after LASIK in eyes with suspicious topography.

    Science.gov (United States)

    Santhiago, Marcony R; Smadja, David; Wilson, Steven E; Krueger, Ronald R; Monteiro, Mario L R; Randleman, J Bradley

    2015-04-01

    To investigate the association of the percent tissue altered (PTA) with the occurrence of ectasia after LASIK in eyes with suspicious preoperative corneal topography. This retrospective comparative case-control study compared associations of reported ectasia risk factors in 129 eyes, including 57 eyes with suspicious preoperative Placido-based corneal topography that developed ectasia after LASIK (suspect ectasia group), 32 eyes with suspicious topography that remained stable for at least 3 years after LASIK (suspect control group), and 30 eyes that developed ectasia with bilateral normal topography (normal topography ectasia group). Groups were subdivided based on topographic asymmetry into high- or low-suspect groups. The PTA, preoperative central corneal thickness (CCT), residual stromal bed (RSB), and age (years) were evaluated in univariate and multivariate analyses. Average PTA values for normal topography ectasia (45), low-suspect ectasia (39), high-suspect ectasia (36), low-suspect control (32), and high-suspect control (29) were significantly different from one another in all comparisons (P topography ectasia groups, and CCT was not significantly different between any groups. Stepwise logistic regression revealed the PTA as the most significant independent variable (P topography. Less tissue alteration, or a lower PTA value, was necessary to induce ectasia in eyes with more remarkable signs of topographic abnormality, and PTA provided better discriminative capabilities than RSB for all study populations. Copyright 2015, SLACK Incorporated.

  19. Separating Facts from Fiction: Linguistic Models to Classify Suspicious and Trusted News Posts on Twitter

    Energy Technology Data Exchange (ETDEWEB)

    Volkova, Svitlana; Shaffer, Kyle J.; Jang, Jin Yea; Hodas, Nathan O.

    2017-07-30

    Pew research polls report 62 percent of U.S. adults get news on social media (Gottfried and Shearer, 2016). In a December poll, 64 percent of U.S. adults said that “made-up news” has caused a “great deal of confusion” about the facts of current events (Barthel et al., 2016). Fabricated stories spread in social media, ranging from deliberate propaganda to hoaxes and satire, contributes to this confusion in addition to having serious effects on global stability. In this work we build predictive models to classify 130 thousand news tweets as suspicious or verified, and predict four subtypes of suspicious news – satire, hoaxes, clickbait and propaganda. We demonstrate that neural network models trained on tweet content and social network interactions outperform lexical models. Unlike previous work on deception detection, we find that adding syntax and grammar features to our models decreases performance. Incorporating linguistic features, including bias and subjectivity, improves classification results, however social interaction features are most informative for finer-grained separation between our four types of suspicious news posts.

  20. Angiosonography in suspicious breast lesions with non-diagnostic FNAC: comparison with power Doppler US.

    Science.gov (United States)

    Caumo, F; Carbognin, G; Casarin, A; Pinali, L; Vasori, S; D'Onofrio, M; Pozzi Mucelli, R

    2006-02-01

    The purpose of this study was to evaluate the accuracy of angiosonography in comparison with colour Doppler ultrasound (US) in the discrimination of suspicious breast lesions with nondiagnostic fine-needle aspiration cytology (FNAC). Pre-operative Power Doppler US and angiosonography were prospectively performed in 20 suspicious breast lesions with non-diagnostic FNAC. A second-generation US contrast agent was utilised with a high-frequency transducer and a contrast-specific algorithm (low acoustic pressure CnTI). The enhancement characteristics of all lesions were analysed using qualitative and quantitative parameters obtained from time-intensity curves with the different imaging modalities. The final diagnosis was confirmed at pathology in all cases. Microvessel density (MVD) was assessed in the surgical specimen using CD34. The correct assessment of biological behaviour was achieved in all cases by angiosonography (sensitivity of 100%; specificity of 91%) and colour Doppler US (45% sensitivity; 78% specificity). MVD correlated with the biological behaviour. Angiosonography is more accurate than colour Doppler US in the correct assessment of biological behaviour of suspicious breast lesions.

  1. Traveling Safely with Medicines

    Science.gov (United States)

    ... Medications Safely My Medicine List How to Administer Traveling Safely with Medicines Planes, trains, cars – even boats ... your trip, ask your pharmacist about how to travel safely with your medicines. Make sure that you ...

  2. Diffusion-weighted magnetic resonance imaging in the assessment of ovarian masses with suspicious features: Strengths and challen

    Directory of Open Access Journals (Sweden)

    Sahar Mansour

    2015-12-01

    Conclusion: DWI supported by conventional MRI data can confirm or exclude malignancy in suspicious ovarian masses. The combined analysis of quantitative and qualitative criteria and knowledge of the sequence pitfalls are required.

  3. Safe Handling of Radioisotopes

    International Nuclear Information System (INIS)

    1958-01-01

    Under its Statute the International Atomic Energy Agency is empowered to provide for the application of standards of safety for protection against radiation to its own operations and to operations making use of assistance provided by it or with which it is otherwise directly associated. To this end authorities receiving such assistance are required to observe relevant health and safety measures prescribed by the Agency. As a first step, it has been considered an urgent task to provide users of radioisotopes with a manual of practice for the safe handling of these substances. Such a manual is presented here and represents the first of a series of manuals and codes to be issued by the Agency. It has been prepared after careful consideration of existing national and international codes of radiation safety, by a group of international experts and in consultation with other international bodies. At the same time it is recommended that the manual be taken into account as a basic reference document by Member States of the Agency in the preparation of national health and safety documents covering the use of radioisotopes.

  4. Role of 3D power Doppler ultrasound in the further characterization of suspicious breast masses.

    Science.gov (United States)

    Kupeli, Ali; Kul, Sibel; Eyuboglu, Ilker; Oguz, Sukru; Mungan, Sevdegul

    2016-01-01

    To investigate effectiveness of vascular indices obtained with 3D power Doppler ultrasound in the further characterization of breast masses and prevention of unnecessary biopsies. Between April 2013 and March 2014, 109 patients (age range, 17-85 years; mean age, 47 years) with 117 radiologically or clinically suspicious breast masses were prospectively evaluated with 3DPDUS before biopsy. Mass volume (MV), vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using Virtual Organ Computer-aided Analysis (VOCAL) software and they were correlated with the final diagnosis. Cutoff values of vascular indices were determinated and diagnostic efficacy was calculated with receiver operating curve (ROC) analysis. All vascular indices, age of patients and tumor volume were significantly lower in benign masses compared with malignant ones (p<0.001). AUCs were 0.872, 0.867 and 0.789 for VI, VFI and FI, respectively. The diagnostic efficacy of VI (for cutoff 1.1; 83% sensitivity, 82% specificity and 82% accuracy) and VFI (for cutoff 0.4; 80% sensitivity, 83% specificity and 80% accuracy) were significantly higher than FI (for cutoff 33,9; 73% sensitivity, 69% specificity and 71% accuracy). It was found that with the use of vascular indices of 3DPDUS in the further characterization of suspicious breast masses between 24% to 37% of unnecessary biopsies could have been avoided. The vascular indices obtained with 3DPDUS seem reliable in the further characterization of suspicious breast masses and might be used to decrease unnecessary biopsies. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  5. Phishing suspiciousness in older and younger adults: The role of executive functioning.

    Directory of Open Access Journals (Sweden)

    Brandon E Gavett

    Full Text Available Phishing is the spoofing of Internet websites or emails aimed at tricking users into entering sensitive information, with such goals as financial or identity theft. The current study sought to determine whether age is associated with increased susceptibility to phishing and whether tests of executive functioning can predict phishing susceptibility. A total of 193 cognitively intact participants, 91 younger adults and 102 older adults, were primarily recruited through a Psychology department undergraduate subject pool and a gerontology research registry, respectively. The Executive Functions Module from the Neuropsychological Assessment Battery and the Iowa Gambling Task were the primary cognitive predictors of reported phishing suspiciousness. Other predictors included age group (older vs. younger, sex, education, race, ethnicity, prior knowledge of phishing, prior susceptibility to phishing, and whether or not browsing behaviors were reportedly different in the laboratory setting versus at home. A logistic regression, which accounted for a 22.7% reduction in error variance compared to the null model and predicted phishing suspiciousness with 73.1% (95% CI [66.0, 80.3] accuracy, revealed three statistically significant predictors: the main effect of education (b = 0.58, SE = 0.27 and the interactions of age group with prior awareness of phishing (b = 2.31, SE = 1.12 and performance on the Neuropsychological Assessment Battery Mazes test (b = 0.16, SE = 0.07. Whether or not older adults reported being suspicious of the phishing attacks used in this study was partially explained by educational history and prior phishing knowledge. This suggests that simple educational interventions may be effective in reducing phishing vulnerability. Although one test of executive functioning was found useful for identifying those at risk of phishing susceptibility, four tests were not found to be useful; these results speak to the need for more ecologically valid

  6. Bioactive substances

    Digital Repository Service at National Institute of Oceanography (India)

    Wahidullah, S.

    Chemistry related to certain bioactive molecules, from Indian Ocean Region, developed into drugs or which served as models for the synthesis of more effective bioactive substances or in use in fundamental studies of physiological and biochemical...

  7. Psychotoxic Substances

    Science.gov (United States)

    1964-11-16

    halluci- nations , disturbances of body perception, depersonalization symptoms, and a "psychotic" status. Also with the derivatives, the individual...the substance had also local anesthetic properties. After clinical testing, ibogaine was then used as stimulans for neurasthenics and convalescents1 1 3...con- siderably disturbed by this group of substances. The optic halluci- nations consist to a small extent in scenic proceedings of actions, more

  8. Informing cancer patient based on his type of personality: the suspicious (paranoid) patient.

    Science.gov (United States)

    Kallergis, G

    2013-01-01

    Imparting bad news had always been an unpleasant task for the physician, as shown from ancient years to our days. In the healthcare sector and as far as the cancer patient is concerned, the imparting of bad news is performed by the patient's doctor within a therapeutic relationship of course. The fundamental question is how a therapist could tailor the information to any patient and if "Is it possible to determine who should be told what, when and how ?". The aim of this paper was to describe the suspicious character or type of personality thoroughly so that any physician can make a diagnosis and tailor the information strategy to the patient's needs. As method of research was used the qualitative method through groups with doctors and nurses, while research within groups lasted for 5 years. The degree of informing of the suspicious personality in the range "minimal - small - medium - large - very large" is : the degree of denial varies between large and very large. The degree of informing varies between medium and small and sometimes minimal. Informing the Family: The hardest family to deal with. Pay attention to litigious mania. Avoid confrontation or be drawn into agreeing with the family views.

  9. The value of preoperative ultrasound guided fine-needle aspiration cytology of radiologically suspicious axillary lymph nodes in breast cancer

    Directory of Open Access Journals (Sweden)

    Torill Sauer

    2014-01-01

    Full Text Available Background: Preoperative ultrasound (US and eventually US-guided fine-needle aspiration cytology (FNAC of suspicious axillary lymph nodes (ALN is a standard procedure in the work-up of suspicious breast lesions. Preoperative US FNAC may prevent sentinel node biopsy (SNB procedure in 24-30% of patients with early stage breast carcinoma. The aim of this study was to evaluate the institutional results of this preoperative diagnostic procedure. Materials and Methods: A total of 182 cases of preoperative FNAC of suspicious ALN where retrieved from the pathology files. The results were compared with the final histology and staging. False negative (FN FNAC cases were reviewed and possibly missed metastatic cases (2 were immunostained with the epithelial marker AE1/AE3. Results: There were no false positives, whereas 16 cases were FN. In all but one case the FN′s represented sampling error. Half of the 16 FN cases in this series were macrometastases. Discussion: About 83% of the preoperatively aspirated cases were N+, indicating that a radiologically suspicious ALN has a very high risk of being metastatic. Preoperative US guided FNAC from radiologically suspicious ALN is highly efficient in detecting metastases. Depending on national guidelines, a preoperative, positive ALN FNAC might help to stratify the patients as to SNB and/or ALN dissection.

  10. Thyroid nodules with highly suspicious ultrasonographic features, but with benign cytology on two occasions: is malignancy still possible?

    International Nuclear Information System (INIS)

    Rosario, Pedro Weslley; Calsolari, Maria Regina

    2016-01-01

    There is no information about the frequency of malignancy specifically in the case of thyroid nodules with highly suspicious sonographic features, but with two fine needle aspiration (FNA) showing benign cytology. This was the objective of the study. Subjects and methods: We report the results of 105 patients with thyroid nodules considered 'highly suspicious' according to the ultrasonographic classification of American Thyroid Association, in whom FNA revealed benign cytology on two occasions (interval of 6 months). Results: Thyroidectomy was performed in 11 cases due to desire of the patient or significant growth of the nodule. In these patients, cytology continued to be benign in 9, was non-diagnostic in 1, and suspicious in 1. Histology revealed papillary carcinoma in only one nodule. In patients in whom a third FNA was obtained for this study (n = 94), cytology continued to be benign in 86, became non-diagnostic in 5, indeterminate in 2, and suspicious in 1. The last 8 patients (with non-benign cytology) were submitted to thyroidectomy and histology revealed malignancy in only one nodule. Conclusion: The rate of malignancy found here for nodules with highly suspicious sonographic features, even after two FNA showing benign cytology, was 2%. We believe that in these cases, the continuation of follow-up consisting of ultrasound at intervals of 2 years may still be adequate. (author)

  11. Thyroid nodules with highly suspicious ultrasonographic features, but with benign cytology on two occasions: is malignancy still possible?

    Energy Technology Data Exchange (ETDEWEB)

    Rosario, Pedro Weslley; Calsolari, Maria Regina, E-mail: pedrowsrosario@gmail.com [Santa Casa de Belo Horizonte, MG (Brazil)

    2016-11-01

    There is no information about the frequency of malignancy specifically in the case of thyroid nodules with highly suspicious sonographic features, but with two fine needle aspiration (FNA) showing benign cytology. This was the objective of the study. Subjects and methods: We report the results of 105 patients with thyroid nodules considered 'highly suspicious' according to the ultrasonographic classification of American Thyroid Association, in whom FNA revealed benign cytology on two occasions (interval of 6 months). Results: Thyroidectomy was performed in 11 cases due to desire of the patient or significant growth of the nodule. In these patients, cytology continued to be benign in 9, was non-diagnostic in 1, and suspicious in 1. Histology revealed papillary carcinoma in only one nodule. In patients in whom a third FNA was obtained for this study (n = 94), cytology continued to be benign in 86, became non-diagnostic in 5, indeterminate in 2, and suspicious in 1. The last 8 patients (with non-benign cytology) were submitted to thyroidectomy and histology revealed malignancy in only one nodule. Conclusion: The rate of malignancy found here for nodules with highly suspicious sonographic features, even after two FNA showing benign cytology, was 2%. We believe that in these cases, the continuation of follow-up consisting of ultrasound at intervals of 2 years may still be adequate. (author)

  12. Safe Kids Worldwide

    Science.gov (United States)

    ... Blog Videos Newsletter facebook twitter instagram pinterest gplus youtube Search Menu Why It Matters Who We Are What We Do Find Your Safe Kids Safe Kids Day Main menu Keeping All Kids Safe Safety Tips Get Involved 4 Star Charity Donate Text Burns and Scalds 4 tips ...

  13. "Same Room, Safe Place".

    Science.gov (United States)

    Keene Woods, Nikki

    2017-04-01

    There are many different professional stances on safe sleep and then there is the reality of caring for a newborn. There is a debate among professionals regarding safe sleep recommendations. The continum of recommendations vary from the American Academy of Pediatrics (AAP) Safe Sleep Guidelines to the bed-sharing recommendations from the Mother-Baby Behavioral Sleep Laboratory. The lack of consistent and uniform safe sleep recommendations from health professionals has been confusing for families but has more recently raised a real professional ethical dilemma. Despite years of focused safe sleep community education and interventions, sleep-related infant deaths are on the rise in many communities. This commentary calls for a united safe sleep message from all health professionals to improve health for mothers and infants most at-risk, "Same Room, Safe Place."

  14. Shared Substance

    DEFF Research Database (Denmark)

    Gjerlufsen, Tony; Klokmose, Clemens Nylandsted; Eagan, James

    2011-01-01

    This paper presents a novel middleware for developing flexible interactive multi-surface applications. Using a scenario-based approach, we identify the requirements for this type of applications. We then introduce Substance, a data- oriented framework that decouples functionality from data, and S...

  15. Visualization of suspicious lesions in breast MRI based on intelligent neural systems

    Science.gov (United States)

    Twellmann, Thorsten; Lange, Oliver; Nattkemper, Tim Wilhelm; Meyer-Bäse, Anke

    2006-05-01

    Intelligent medical systems based on supervised and unsupervised artificial neural networks are applied to the automatic visualization and classification of suspicious lesions in breast MRI. These systems represent an important component of future sophisticated computer-aided diagnosis systems and enable the extraction of spatial and temporal features of dynamic MRI data stemming from patients with confirmed lesion diagnosis. By taking into account the heterogenity of the cancerous tissue, these techniques reveal the malignant, benign and normal kinetic signals and and provide a regional subclassification of pathological breast tissue. Intelligent medical systems are expected to have substantial implications in healthcare politics by contributing to the diagnosis of indeterminate breast lesions by non-invasive imaging.

  16. Student Perceptions of Auditor Responses to Evidence of Suspicious Activities: An Experimental Assessment

    Directory of Open Access Journals (Sweden)

    David S Murphy

    2015-12-01

    Full Text Available This study assessed student perceptions of auditor responses to evidence that a client failed to respond appropriately to suspicious activities that could indicate money laundering. Subjects were presented with a series of randomized cases in which partner type (new vs. experienced, firm type (regional vs. international and audit fee materiality (not material, material to the local office only, material to the firm were manipulated asked to indicate their perceptions of the likelihood that an audit partner would discuss such evidence with the client, and the likelihood that the issue would be disclosed by the auditor. Both partner type and audit fee materiality was found to have significant effects on perceived likelihoods.

  17. Computerized classification of suspicious regions in chest radiographs using subregion Hotelling observers

    International Nuclear Information System (INIS)

    Baydush, Alan H.; Catarious, David M. Jr.; Lo, Joseph Y.; Abbey, Craig K.; Floyd, Carey E. Jr.

    2001-01-01

    We propose to investigate the use of subregion Hotelling observers (SRHOs) in conjunction with perceptrons for the computerized classification of suspicious regions in chest radiographs for being nodules requiring follow up. Previously, 239 regions of interest (ROIs), each containing a suspicious lesion with proven classification, were collected. We chose to investigate the use of SRHOs as part of a multilayer classifier to determine the presence of a nodule. Each SRHO incorporates information about signal, background, and noise correlation for classification. For this study, 225 separate Hotelling observers were set up in a grid across each ROI. Each separate observer discriminates an 8 by 8 pixel area. A round robin sampling scheme was used to generate the 225 features, where each feature is the output of the individual observers. These features were then rank ordered by the magnitude of the weights of a perceptron. Once rank ordered, subsets of increasing number of features were selected to be used in another perceptron. This perceptron was trained to minimize mean squared error and the output was a continuous variable representing the likelihood of the region being a nodule. Performance was evaluated by receiver operating characteristic (ROC) analysis and reported as the area under the curve (A Z ). The classifier was optimized by adding additional features until the A Z declined. The optimized subset of observers then were combined using a third perceptron. A subset of 80 features was selected which gave an A Z of 0.972. Additionally, at 98.6% sensitivity, the classifier had a specificity of 71.3% and increased the positive predictive value from 60.7% to 84.1%. Preliminary results suggest that using SRHOs in combination with perceptrons can provide a successful classification scheme for pulmonary nodules. This approach could be incorporated into a larger computer aided detection system for decreasing false positives

  18. Introducing a Model for Suspicious Behaviors Detection in Electronic Banking by Using Decision Tree Algorithms

    Directory of Open Access Journals (Sweden)

    Rohulla Kosari Langari

    2014-02-01

    Full Text Available Change the world through information technology and Internet development, has created competitive knowledge in the field of electronic commerce, lead to increasing in competitive potential among organizations. In this condition The increasing rate of commercial deals developing guaranteed with speed and light quality is due to provide dynamic system of electronic banking until by using modern technology to facilitate electronic business process. Internet banking is enumerate as a potential opportunity the fundamental pillars and determinates of e-banking that in cyber space has been faced with various obstacles and threats. One of this challenge is complete uncertainty in security guarantee of financial transactions also exist of suspicious and unusual behavior with mail fraud for financial abuse. Now various systems because of intelligence mechanical methods and data mining technique has been designed for fraud detection in users’ behaviors and applied in various industrial such as insurance, medicine and banking. Main of article has been recognizing of unusual users behaviors in e-banking system. Therefore, detection behavior user and categories of emerged patterns to paper the conditions for predicting unauthorized penetration and detection of suspicious behavior. Since detection behavior user in internet system has been uncertainty and records of transactions can be useful to understand these movement and therefore among machine method, decision tree technique is considered common tool for classification and prediction, therefore in this research at first has determinate banking effective variable and weight of everything in internet behaviors production and in continuation combining of various behaviors manner draw out such as the model of inductive rules to provide ability recognizing of different behaviors. At least trend of four algorithm Chaid, ex_Chaid, C4.5, C5.0 has compared and evaluated for classification and detection of exist

  19. Safe havens in Europe

    DEFF Research Database (Denmark)

    Paldam, Martin

    2013-01-01

    Eleven safe havens exist in Europe providing offshore banking and low taxes. Ten of these states are very small while Switzerland is moderately small. All 11 countries are richer than their large neighbors. It is shown that causality is from small to safe haven to wealth, and that theoretically...... equilibriums are likely to exist where a certain regulation is substantially lower in a small country than in its big neighbor. This generates a large capital inflow to the safe havens. The pool of funds that may reach the safe havens is shown to be huge. It is far in excess of the absorptive capacity...... of the safe havens, but it still explains, why they are rich. Microstates offer a veil of anonymity to funds passing through, and Switzerland offers safe storage of funds....

  20. Computed tomography is not justified in every pediatric blunt trauma patient with a suspicious mechanism of injury.

    Science.gov (United States)

    Hershkovitz, Yehuda; Zoarets, Itai; Stepansky, Albert; Kozer, Eran; Shapira, Zahar; Klin, Baruch; Halevy, Ariel; Jeroukhimov, Igor

    2014-07-01

    Computed tomography (CT) has become an important tool for the diagnosis of intra-abdominal and chest injuries in patients with blunt trauma. The role of CT in conscious asymptomatic patients with a suspicious mechanism of injury remains controversial. This controversy intensifies in the management of pediatric blunt trauma patients, who are much more susceptible to radiation exposure. The objective of this study was to evaluate the role of abdominal and chest CT imaging in asymptomatic pediatric patients with a suspicious mechanism of injury. Forty-two pediatric patients up to 15 years old were prospectively enrolled. All patients presented with a suspicious mechanism of blunt trauma and multisystem injury. They were neurologically intact and had no signs of injury to the abdomen or chest. Patients underwent CT imaging of the chest and abdomen as part of the initial evaluation. Thirty-one patients (74%) had a normal CT scan. Two patients of 11 with an abnormal CT scan required a change in management and were referred for observation in the Intensive Care Unit. None of the patients required surgical intervention. The routine use of CT in asymptomatic pediatric patients with a suspicious mechanism of blunt trauma injury is not justified. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Are Detox Diets Safe?

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Are Detox Diets Safe? KidsHealth / For Teens / Are Detox Diets ... seguras las dietas de desintoxicación? What Is a Detox Diet? The name sounds reassuring — everyone knows that ...

  2. Chernobyl new safe confinement

    International Nuclear Information System (INIS)

    Dodd, L.

    2011-01-01

    The author presents the new safe confinement that will be commissioned at Unit 4 of the Chernobyl NPP in 2015. The confinement will ensure that Chernobyl Unit 4 will be placed in an environmentally safe condition for at least next 100 years. The article highlights the current work status, future perspectives and the feasibility of confinement concept [ru

  3. Asymptotically Safe Dark Matter

    DEFF Research Database (Denmark)

    Sannino, Francesco; Shoemaker, Ian M.

    2015-01-01

    We introduce a new paradigm for dark matter (DM) interactions in which the interaction strength is asymptotically safe. In models of this type, the coupling strength is small at low energies but increases at higher energies, and asymptotically approaches a finite constant value. The resulting...... searches are the primary ways to constrain or discover asymptotically safe dark matter....

  4. Adaptive Suspicious Prevention for Defending DoS Attacks in SDN-Based Convergent Networks.

    Science.gov (United States)

    Dao, Nhu-Ngoc; Kim, Joongheon; Park, Minho; Cho, Sungrae

    2016-01-01

    The convergent communication network will play an important role as a single platform to unify heterogeneous networks and integrate emerging technologies and existing legacy networks. Although there have been proposed many feasible solutions, they could not become convergent frameworks since they mainly focused on converting functions between various protocols and interfaces in edge networks, and handling functions for multiple services in core networks, e.g., the Multi-protocol Label Switching (MPLS) technique. Software-defined networking (SDN), on the other hand, is expected to be the ideal future for the convergent network since it can provide a controllable, dynamic, and cost-effective network. However, SDN has an original structural vulnerability behind a lot of advantages, which is the centralized control plane. As the brains of the network, a controller manages the whole network, which is attractive to attackers. In this context, we proposes a novel solution called adaptive suspicious prevention (ASP) mechanism to protect the controller from the Denial of Service (DoS) attacks that could incapacitate an SDN. The ASP is integrated with OpenFlow protocol to detect and prevent DoS attacks effectively. Our comprehensive experimental results show that the ASP enhances the resilience of an SDN network against DoS attacks by up to 38%.

  5. 3-T breast magnetic resonance imaging in patients with suspicious microcalcifications on mammography

    Energy Technology Data Exchange (ETDEWEB)

    Stehouwer, B.L.; Merckel, L.G.; Verkooijen, H.M.; Peters, N.H.G.M.; Mali, W.P.T.M.; Veldhuis, W.B.; Bosch, M.A.A.J. van den [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Mann, R.M. [University Medical Center St Radboud, Departement of Radiology, Nijmegen (Netherlands); Duvivier, K.M. [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); VU University Medical Center, Department of Radiology, Amsterdam (Netherlands); Peeters, P.H.M. [University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht (Netherlands)

    2014-03-15

    To investigate the diagnostic value of 3-Tesla (T) breast MRI in patients presenting with microcalcifications on mammography. Between January 2006 and May 2009, 123 patients with mammographically detected BI-RADS 3-5 microcalcifications underwent 3-T breast MRI before undergoing breast biopsy. All MRIs of the histopathologically confirmed index lesions were reviewed by two breast radiologists. The detection rate of invasive carcinoma and ductal carcinoma in situ (DCIS) was evaluated, as well as the added diagnostic value of MRI over mammography and breast ultrasound. At pathology, 40/123 (33 %) lesions proved malignant; 28 (70 %) DCIS and 12 (30 %) invasive carcinoma. Both observers detected all invasive malignancies at MRI, as well as 79 % (observer 1) and 86 % (observer 2) of in situ lesions. MRI in addition to conventional imaging led to a significant increase in area under the receiver operating characteristic (ROC) curve from 0.67 (95 % CI 0.56-0.79) to 0.79 (95 % CI 0.70-0.88, observer 1) and to 0.80 (95 % CI 0.71-0.89, observer 2), respectively. 3-T breast MRI was shown to add significant value to conventional imaging in patients presenting with suspicious microcalcifications on mammography. (orig.)

  6. Automatic detection of suspicious behavior of pickpockets with track-based features in a shopping mall

    Science.gov (United States)

    Bouma, Henri; Baan, Jan; Burghouts, Gertjan J.; Eendebak, Pieter T.; van Huis, Jasper R.; Dijk, Judith; van Rest, Jeroen H. C.

    2014-10-01

    Proactive detection of incidents is required to decrease the cost of security incidents. This paper focusses on the automatic early detection of suspicious behavior of pickpockets with track-based features in a crowded shopping mall. Our method consists of several steps: pedestrian tracking, feature computation and pickpocket recognition. This is challenging because the environment is crowded, people move freely through areas which cannot be covered by a single camera, because the actual snatch is a subtle action, and because collaboration is complex social behavior. We carried out an experiment with more than 20 validated pickpocket incidents. We used a top-down approach to translate expert knowledge in features and rules, and a bottom-up approach to learn discriminating patterns with a classifier. The classifier was used to separate the pickpockets from normal passers-by who are shopping in the mall. We performed a cross validation to train and evaluate our system. In this paper, we describe our method, identify the most valuable features, and analyze the results that were obtained in the experiment. We estimate the quality of these features and the performance of automatic detection of (collaborating) pickpockets. The results show that many of the pickpockets can be detected at a low false alarm rate.

  7. Clinical and diagnostic value of preoperative MR mammography and FDG-PET in suspicious breast lesions

    International Nuclear Information System (INIS)

    Walter, C.; Scheidhauer, K.; Theissen, P.; Scharl, A.; Goering, U.J.; Kugel, H.; Krahe, T.; Pietrzyk, U.

    2003-01-01

    Dynamic enhanced magnetic resonance (MR) mammography and fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) of the breast were directly compared preoperatively in suspicious breast lesions. Forty-two breast lesions in 40 patients were examined with a three-dimensional dynamic MR imaging series and FDG-PET. The MR and PET examinations were evaluated separately and the results were compared with the histological findings. The sensitivity and specificity of each method were calculated. The diagnostic value of both modalities as single diagnostic tool and in combination was investigated. Nineteen malignant and 23 benign breast lesions were proven histologically. Magnetic resonance mammography and FDG-PET showed a sensitivity of 89 and 63%, respectively. The specificity was 74 and 91%, respectively. The combination of both imaging methods decreased the not-required biopsies from 55 to 17%. Only one false-negative finding - a patient pre-treated with chemotherapy - was observed in both methods. The combination of MR mammography and FDG-PET can help to decrease biopsies of benign breast lesions. Because of their high cost, these modalities should only be used in problematic cases to either rule out or to demonstrate malignancy. The best diagnostic strategy is achieved using MR mammography first. If the diagnosis is still questionable, FDG-PET can be performed. (orig.)

  8. Safe Sleep for Babies

    Science.gov (United States)

    ... 5 MB] Read the MMWR Science Clips Safe Sleep for Babies Eliminating hazards Recommend on Facebook Tweet ... Page Problem Every year, there are thousands of sleep-related deaths among babies. View large image and ...

  9. Safe operating envelope

    Energy Technology Data Exchange (ETDEWEB)

    Oliva, N [Ontario Hydro, Toronto, ON (Canada)

    1997-12-01

    Safe Operating Envelope is described representing: The outer bound of plant conditions within which day-to-day plant operation must be maintained in order to comply with regulatory requirements, associated safety design criteria and corporate nuclear safety goals. Figs.

  10. The first safe country

    Directory of Open Access Journals (Sweden)

    Raffaela Puggioni

    2012-06-01

    Full Text Available The Dublin II Regulation makes the first safe country of refuge solelyresponsible for refugees and asylum seekers. In the case of Italy, thefirst responsible country has not been acting responsibly.

  11. Buying & Using Medicine Safely

    Science.gov (United States)

    ... Reducers Safe Daily Use of Aspirin Medication Health Fraud Resources for You FDA Consumer Updates (Drugs) Page ... feeds Follow FDA on Twitter Follow FDA on Facebook View FDA videos on YouTube View FDA photos ...

  12. Karate: Keep It Safe.

    Science.gov (United States)

    Jordan, David

    1981-01-01

    Safety guidelines for each phase of a karate practice session are presented to provide an accident-free and safe environment for teaching karate in a physical education or traditional karate training program. (JMF)

  13. Safe operating envelope

    International Nuclear Information System (INIS)

    Oliva, N.

    1997-01-01

    Safe Operating Envelope is described representing: The outer bound of plant conditions within which day-to-day plant operation must be maintained in order to comply with regulatory requirements, associated safety design criteria and corporate nuclear safety goals. Figs

  14. Safe driving for teens

    Science.gov (United States)

    Driving and teenagers; Teens and safe driving; Automobile safety - teenage drivers ... months before taking friends as passengers. Teenage-related driving deaths occur more often in certain conditions. OTHER SAFETY TIPS FOR TEENS Reckless driving is still a ...

  15. Removing Hair Safely

    Science.gov (United States)

    ... For Consumers Home For Consumers Consumer Updates Removing Hair Safely Share Tweet Linkedin Pin it More sharing ... related to common methods of hair removal. Laser Hair Removal In this method, a laser destroys hair ...

  16. Medications: Using Them Safely

    Science.gov (United States)

    ... to Safely Give Ibuprofen Childproofing and Preventing Household Accidents Medicines for Diabetes Complementary and Alternative Medicine How Do Pain Relievers Work? What Medicines Are and What They Do Medicines ...

  17. DroidSafe

    Science.gov (United States)

    2016-12-01

    Massachusetts Avenue, Build E19-750 Cambridge , MA 02139-4307 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS...Activity objects illustrating the challenges of points-to and information flow analysis...measure how many malicious flows Droid- Safe was able to detect). As these results illustrate , DroidSafe implements an analysis of unprece- dented

  18. Safe biodegradable fluorescent particles

    Science.gov (United States)

    Martin, Sue I [Berkeley, CA; Fergenson, David P [Alamo, CA; Srivastava, Abneesh [Santa Clara, CA; Bogan, Michael J [Dublin, CA; Riot, Vincent J [Oakland, CA; Frank, Matthias [Oakland, CA

    2010-08-24

    A human-safe fluorescence particle that can be used for fluorescence detection instruments or act as a safe simulant for mimicking the fluorescence properties of microorganisms. The particle comprises a non-biological carrier and natural fluorophores encapsulated in the non-biological carrier. By doping biodegradable-polymer drug delivery microspheres with natural or synthetic fluorophores, the desired fluorescence can be attained or biological organisms can be simulated without the associated risks and logistical difficulties of live microorganisms.

  19. Evaluation of a mammographic stereotactic device for localization, fine-needle aspiration cytologic studies, and core biopsy of suspicious lesions

    International Nuclear Information System (INIS)

    Fajardo, L.J.; Davey, G.A.

    1988-01-01

    Mammography-guided interventional breast procedures, such as preoperative localization, fine-needle aspiration cytology (FNAC), and core biopsy of suspicious lesions, require accurate three-dimensional localization. The authors have evaluated a prototype stereotactic mammography device for localizing abnormalities with both phantom and clinical studies. Twenty-six localizations on a phantom were within 0.5 mm +- 0.93 (standard deviation) from the lesions; accuracy in clinical procedures was within 0.6 mm +- 0.8. Procedures are performed an average of 8 minutes faster with this device. They are prospectively evaluating mammography-guided FNAC and core biopsy of suspicious lesions in 100 patients. Results of FNAC performed without the stereotactic device agreed with results of open surgical biopsy in six of eight patients; results of core biopsy agreed in seven of eight

  20. Error in laboratory report data for platelet count assessment in patients suspicious for dengue: a note from observation

    Directory of Open Access Journals (Sweden)

    Somsri Wiwanitkit

    2016-08-01

    Full Text Available Dengue is a common tropical infection that is still a global health threat. An important laboratory parameter for the management of dengue is platelet count. Platelet count is an useful test for diagnosis and following up on dengue. However, errors in laboratory reports can occur. This study is a retrospective analysis on laboratory report data of complete blood count in cases with suspicious dengue in a medical center within 1 month period during the outbreak season on October, 2015. According to the studied period, there were 184 requests for complete blood count for cases suspected for dengue. From those 184 laboratory report records, errors can be seen in 12 reports (6.5%. This study demonstrates that there are considerable high rate of post-analytical errors in laboratory reports. Interestingly, the platelet count in those erroneous reports can be unreliable and ineffective or problematic when it is used for the management of dengue suspicious patients.

  1. Combining PET/CT with serum tumor markers to improve the evaluation of histological type of suspicious lung cancers.

    Science.gov (United States)

    Jiang, Rifeng; Dong, Ximin; Zhu, Wenzhen; Duan, Qing; Xue, Yunjing; Shen, Yanxia; Zhang, Guopeng

    2017-01-01

    Histological type is important for determining the management of patients with suspicious lung cancers. In this study, PET/CT combined with serum tumor markers were used to evaluate the histological type of lung lesions. Patients with suspicious lung cancers underwent 18F-FDG PET/CT and serum tumor markers detection. SUVmax of the tumor and serum levels of tumor markers were acquired. Differences in SUVmax and serum levels of tumor markers among different histological types of lung cancers and between EGFR mutation statues of adenocarcinoma were compared. The diagnostic efficiencies of SUVmax alone, each serum tumor marker alone, combined tumor markers and the combination of both methods were further assessed and compared. SCC had the highest level of SUVmax, followed by SCLC and adenocarcinoma, and benign lesions had a lowest level. CYFRA21-1 and SCC-Ag were significantly higher in SCC, NSE was significantly higher in SCLC (Ptumor marker or SUVmax alone. When combined, the AUC, sensitivity and specificity increased significantly (Ptumor markers (P>0.05 for all). SUVmax and serum tumor markers show values in evaluating the histological types of suspicious lung cancers. When properly combined, the diagnostic efficiency can increase significantly.

  2. Revaluation of breast cytology with pathologist on-site of lesions with suspicious sonographic features

    Energy Technology Data Exchange (ETDEWEB)

    Capalbo, Emanuela, E-mail: emanuelacapalbo@tiscalinet.it [Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano Via Di Rudinì, Milano, 20142 Italy (Italy); Sajadidehkordi, Farideh, E-mail: faridehit@yahoo.it [Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano Via Di Rudinì, Milano, 20142 Italy (Italy); Colombi, Claudio; Ticha, Vladimira; Moretti, Angela, E-mail: info.radiologia@sancarlo.mi.it [Dipartimento di Scienze Diagnostiche, UOC di Radiologia Diagnostica ed Interventistica, A.O San Carlo Borromeo. Via Pio II, 3, 20153 Milano (Italy); Peli, Michela, E-mail: peli.michela@gmail.com [Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano Via Di Rudinì, Milano, 20142 Italy (Italy); Cosentino, Maria, E-mail: maria-cosentino@tiscali.it [Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano Via Di Rudinì, Milano, 20142 Italy (Italy); Lovisatti, Maria, E-mail: marialovisatti@hotmail.com [Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano Via Di Rudinì, Milano, 20142 Italy (Italy); Berti, Elisabetta, E-mail: eliberti@hotmail.it [Dipartimento di Scienze Diagnostiche, UOC di Anatomia Patologica, A.O San Carlo Borromeo. Via Pio II, 3, Milano 20153 (Italy); Cariati, Maurizio, E-mail: info.radiologia@sancarlo.mi.it [Dipartimento di Scienze Diagnostiche, UOC di Radiologia Diagnostica ed Interventistica, A.O San Carlo Borromeo. Via Pio II, 3, 20153 Milano (Italy)

    2013-09-15

    Objective: Evaluating correlation estimation between diagnostic ultrasound (U.S.) of breast lesions and fine needle aspiration cytology (FNAC), and the correlation between cytology and histology (I) of these lesions undergo surgery. Materials and methods: In 2010 we performed 1589 ultrasound breast. We identified 210 suspicious lesions to be subjected to FNAC, which was performed with pathologist on site, and extemporaneous analysis of the sample to assess their appropriateness. We classified the lesions in 5 ultrasound (U) classes according to the criteria defined by Echographic BIRADS Lexicon. The results of cytology were classified in 5 classes (C) according to the guidelines of F.O.N.Ca.M. Then we evaluated the diagnostic correlation between U.S. and FNAC, and between FNAC and Histology. Results: The distribution of lesions in U classes was: 57U2, 55U3, 36U4 and 62U5. The diagnostic concordance between U and FNAC was 96.7%, with a sensitivity of 98%, specificity 93%, negative and positive predictive value respectively of 94.9% and 97.3%, and diagnostic accuracy of 96.6%. The 98 patients with C4-C5 lesions were subjected to surgery and the histology confirmed high-grade malignancy of lesions with a concordance of 99.7%. Conclusions: Having achieved high diagnostic concordance between U and FNAC, and then between FNAC and histology, we may say that the FNAC, less invasive and traumatic for the patient than needle biopsy (CB), may be still a valid method when performed with pathologist on-site to assess the adequacy of the sample taken.

  3. Ultrasound guided core biopsy of suspicious mammographic calcifications using high frequency and power Doppler ultrasound

    International Nuclear Information System (INIS)

    Teh, W.L.; Wilson, A.R.M; Evans, A.J.; Burrell, H.; Pinder, S.E.; Ellis, I.O.

    2000-01-01

    AIM: The pre-operative diagnosis of suspicious mammographic microcalcifications usually requires stereotactic needle biopsy. The aim of this study was to evaluate if high frequency 13 MHz ultrasound (HFUS) and power Doppler (PD) can aid visualization and biopsy of microcalcifications. MATERIALS AND METHODS: Forty-four consecutive patients presenting with microcalcifications without associated mammographic or palpable masses were examined with HFUS and PD. Ultrasound-guided core biopsy (USCB) was performed where possible. Stereotactic biopsy was carried out when US-guided biopsy was unsuccessful. Surgery was performed if a diagnosis of malignancy was made on core biopsy or if the repeat core biopsy was non-diagnostic. RESULTS: Forty-one patients (93%) had ultrasound abnormalities corresponding to mammographic calcification. USCB was performed on 37 patients. In 29/37, USCB obtained a definitive result (78.4%). USCB was non-diagnostic in 4/9 benign (44.4%) and 4/28 (14.3%) malignant lesions biopsied. The complete and absolute sensitivities for malignancy using USCB were 85.7% (24/28) and 81% (23/28), respectively. USCB correctly identified invasive disease in 12/23 (52.2%) cases. There was no significant difference in the presence of abnormal flow on PD between benign and malignant lesions. However, abnormal PD vascularity was present in 43.5% of invasive cancer and was useful in directing successful biopsy in eight cases. CONCLUSION: The combination of high frequency US with PD is useful in the detection and guidance of successful needle biopsy of microcalcifications particularly where there is an invasive focus within larger areas of DCIS. Teh, W.L. (2000)

  4. Fusion of classifiers for REIS-based detection of suspicious breast lesions

    Science.gov (United States)

    Lederman, Dror; Wang, Xingwei; Zheng, Bin; Sumkin, Jules H.; Tublin, Mitchell; Gur, David

    2011-03-01

    After developing a multi-probe resonance-frequency electrical impedance spectroscopy (REIS) system aimed at detecting women with breast abnormalities that may indicate a developing breast cancer, we have been conducting a prospective clinical study to explore the feasibility of applying this REIS system to classify younger women (breast cancer. The system comprises one central probe placed in contact with the nipple, and six additional probes uniformly distributed along an outside circle to be placed in contact with six points on the outer breast skin surface. In this preliminary study, we selected an initial set of 174 examinations on participants that have completed REIS examinations and have clinical status verification. Among these, 66 examinations were recommended for biopsy due to findings of a highly suspicious breast lesion ("positives"), and 108 were determined as negative during imaging based procedures ("negatives"). A set of REIS-based features, extracted using a mirror-matched approach, was computed and fed into five machine learning classifiers. A genetic algorithm was used to select an optimal subset of features for each of the five classifiers. Three fusion rules, namely sum rule, weighted sum rule and weighted median rule, were used to combine the results of the classifiers. Performance evaluation was performed using a leave-one-case-out cross-validation method. The results indicated that REIS may provide a new technology to identify younger women with higher than average risk of having or developing breast cancer. Furthermore, it was shown that fusion rule, such as a weighted median fusion rule and a weighted sum fusion rule may improve performance as compared with the highest performing single classifier.

  5. Malignancy rate of biopsied suspicious bone lesions identified on FDG PET/CT

    Energy Technology Data Exchange (ETDEWEB)

    Adams, Hugo J.A.; Kwee, Thomas C. [University Medical Center Utrecht, Department of Radiology and Nuclear Medicine, Utrecht (Netherlands); Klerk, John M.H. de [Meander Medical Center, Department of Nuclear Medicine, Amersfoort (Netherlands); Heggelman, Ben G.F. [Meander Medical Center, Department of Radiology, Amersfoort (Netherlands); Dubois, Stefan V. [Meander Medical Center, Department of Pathology, Amersfoort (Netherlands)

    2016-07-15

    To determine the malignancy rate of bone lesions identified on FDG PET/CT in patients who have undergone CT-guided biopsy because of the suspicion of malignancy. This single-centre retrospective study spanned eight consecutive years and included all patients who underwent both FDG PET/CT and CT-guided bone biopsy because of the suspicion of malignancy. The positive predictive value (PPV) for malignancy was calculated, and different patient and imaging characteristics were compared between malignant and benign bone lesions. Of 102 included patients with bone lesions that all showed FDG uptake exceeding mediastinal uptake, bone biopsy showed a malignant lesion in 91 patients, yielding a PPV for malignancy of 89.2 % (95 % CI 81.7 - 93.9 %). In the 94 patients with bone lesions that showed FDG uptake exceeding liver uptake, bone biopsy showed a malignant lesion in 83 patients, yielding a PPV for malignancy of 88.3 % (95 % CI 80.1 - 93.5 %). Higher age, bone marrow replacement of the lesion seen on CT, expansion of the lesion seen on CT, and presence of multifocal lesions on FDG PET/CT were significantly more frequent in patients with malignant lesions than in those with benign bone lesions (P = 0.044, P = 0.009, P = 0.015, and P = 0.019, respectively). Furthermore, there was a trend towards a higher incidence of cortical destruction (P = 0.056) and surrounding soft tissue mass (P = 0.063) in patients with malignant bone lesions. The PPV for malignancy of suspicious bone lesions identified on FDG PET/CT is not sufficiently high to justify changes in patient management without histopathological confirmation. Nevertheless, ancillary patient and imaging characteristics may increase the likelihood of a malignant bone lesion. (orig.)

  6. Autofluorescence guided diagnostic evaluation of suspicious oral mucosal lesions: opportunities, limitations, and pitfalls

    Science.gov (United States)

    Vigneswaran, Nadarajah

    2011-03-01

    Wide-filed autofluorescence examination is currently considered as a standard of care for screening and diagnostic evaluation of early neoplastic changes of the skin, cervix, lung, bladder, gastrointestinal tract and oral cavity. Naturally occurring fluorophores within the tissue absorb UV and visible light and can re-emit some of this light at longer wavelengths in the form of fluorescence. This non-invasive tissue autofluorescence imaging is used in optical diagnostics, especially in the early detection of cancer. Usually, malignant transformation is associated with thickening of the epithelium, enhanced cellular density due to increased nuclear cytoplasmic ratio which may attenuate the excitation leading to a decrease in collagen autofluorescence. Hence, dysplastic and cancerous tissues often exhibit decreased blue-green autofluorescence and appear darker compared to uninvolved mucosa. Currently, there are three commercially available devices to examine tissue autofluorescence in the oral cavity. In this study we used the oral cancer screening device IdentafiTM 3000 to examine the tissue reflectance and autofluorescence of PML and confounding lesions of the oral cavity. Wide-field autofluorescence imaging enables rapid inspection of large mucosal surfaces, to aid in recognition of suspicious lesions and may also help in discriminate the PML (class 1) from some of the confounding lesions (class II). However, the presence of inflammation or pigments is also associated with loss of stromal autofluorescence, and may give rise to false-positive results with widefield fluorescence imaging. Clinicians who use these autofluorescence based oral cancer screening devices should be aware about the benign oral mucosal lesions that may give false positivity so that unnecessary patient's anxiety and the need for scalpel biopsy can be eliminated.

  7. Economic Impact of Frozen Section for Thyroid Nodules with "Suspicious for Malignancy" Cytology.

    Science.gov (United States)

    Bollig, Craig A; Gilley, David; Lesko, David; Jorgensen, Jeffrey B; Galloway, Tabitha L; Zitsch, Robert P; Dooley, Laura M

    2018-02-01

    Objective To perform a cost analysis of the routine use of intraoperative frozen section (iFS) among patients undergoing a thyroid lobectomy with "suspicious for malignancy" (SUSP) cytology in the context of the 2015 American Thyroid Association guidelines. Study Design Case series with chart review; cost minimization analysis. Setting Academic. Subjects and Methods Records were reviewed for patients with SUSP cytology who underwent thyroid surgery between 2010 and 2015 in which iFS was utilized. The diagnostic test performance of iFS and the frequency of indicated completion/total thyroidectomies based on the 2015 guidelines were calculated. A cost minimization analysis was performed comparing lobectomy, with and without iFS, and the need for completion thyroidectomy according to costs estimated from 2014 data from Medicare, the Bureau of Labor Statistics, and the Nationwide Inpatient Sample. Results Sixty-five patients met inclusion criteria. The malignancy rate was 61.5%, 45% of which was identified intraoperatively. The specificity and positive predictive value were 100%. The negative predictive value and sensitivity were 83% and 95%, respectively. Completion/total thyroidectomy was indicated for 9% of patients; 83% of these individuals had findings on iFS that would have changed management intraoperatively. Application of the new guidelines would have resulted in a significant reduction in the frequency of conversion to a total thyroidectomy when compared with the actual management (26.1% vs 7.7%, P = .005). Performing routine iFS was the less costly scenario, resulting in a savings of $474 per case. Conclusion For patients with SUSP cytology undergoing lobectomy, routine use of iFS would result in decreased health care utilization.

  8. Full-thickness rectal biopsy in children suspicious for Hirschsprung's disease is safe and yields a low number of insufficient biopsies

    DEFF Research Database (Denmark)

    Bjørn, Niels; Rasmussen, Lars; Qvist, Niels

    2018-01-01

    INTRODUCTION: The diagnosis of Hirschsprung's disease (HD) relies on the histological demonstration of aganglionosis in the bowel wall. Biopsies may be obtained by rectal suction biopsy (RSB) or by transanal full-thickness excision biopsy (FTB). The objective of the present study was to evaluate...... the frequency of complications and inconclusive biopsies after FTB in children referred with suspicion of HD. The secondary objective was to calculate the frequency of proven aganglionosis. METHODS: A retrospective chart review was performed of all patients under the age of 16years who underwent transanal FTB...... during the time period of 2008-2014. RESULTS: A total of 555 patients were included in the review. Inconclusive biopsies were found at the primary biopsy in 35 patients (5.9%). Aganglionosis was found in 12% of the cases. The complication rate was 6.6% (39 patients), 85% of which were classified...

  9. Safeness of radiological machinery

    International Nuclear Information System (INIS)

    Yokoyama, Shun

    1979-01-01

    The human factors affecting the safeness of radiological machinery, which are often very big and complicated machines, are described from the stand point of handling. 20 to 50% of the troubles on equipments seem to be caused by men. This percentage will become even higher in highly developed equipments. Human factors have a great influence on the safeness of radiological equipments. As the human factors, there are sensory factors and knowledge factors as well as psychological factors, and the combination of these factors causes mishandling and danger. Medical services at present are divided in various areas, and consist of the teamwork of the people in various professions. Good human relationship, education and control are highly required to secure the safeness. (Kobatake, H.)

  10. Substance Identification Information from EPA's Substance Registry

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Substance Registry Services (SRS) is the authoritative resource for basic information about substances of interest to the U.S. EPA and its state and tribal...

  11. Keeping Food Safe

    Centers for Disease Control (CDC) Podcasts

    2009-05-27

    This CDC Kidtastics podcast discusses things kids and parents can do to help prevent illness by keeping food safe.  Created: 5/27/2009 by National Center for Zoonotic, Vector-Borne, and Enteric Diseases (NCZVED).   Date Released: 5/27/2009.

  12. Effective and Safe Ships

    DEFF Research Database (Denmark)

    Pedersen, Preben Terndrup; Amdahl, Jørgen; Rutgersson, Olle

    1996-01-01

    A Joint Nordic Research project "Effecive and Safe Ships" is presented. The project is aiming to develop methods and tools for quantitative evaluation fo ship safety. This report is the report of the preliminary phase where the plan for the main project is developed. The objectives of the project...

  13. Are EU Banks Safe?

    NARCIS (Netherlands)

    R.J. Theissen (Roel)

    2013-01-01

    markdownabstract__Abstract__ What exactly are the rules banks are subject to, and are they fit for purpose? These are the two questions addressed in this book ‘Are EU banks safe?’ and its descriptive companion book ‘EU banking supervision’. The full rulebook on banks is difficult to find

  14. The safe home project.

    Science.gov (United States)

    Arphorn, Sara; Jiraniratisai, Sopaphan; Rungtakul, Rungsri; Phutta, Nikom

    2011-12-01

    The Thai Health Promotion Foundation supported the Improvement of Quality of Life of Informal Workers project in Ban Luang District, Amphur Photaram, Ratchaburi Province. There were many informal workers in Ban Luang District. Sweet-crispy fish producers in Ban Luang were the largest group among the sweet-crispy fish producers in Thailand. This project was aimed at improving living and working conditions of informal workers, with a focus on the sweet-crispy fish group. Good practices of improved living and working conditions were used to help informal workers build safe, healthy and productive work environments. These informal workers often worked in substandard conditions and were exposed to various hazards in the working area. These hazards included risk of exposure to hot work environment, ergonomics-related injuries, chemical hazards, electrical hazards etc. Ergonomics problems were commonly in the sweet-crispy fish group. Unnatural postures such as prolonged sitting were performed dominantly. One hundred and fifty informal workers participated in this project. Occupational health volunteers were selected to encourage occupational health and safety in four groups of informal workers in 2009. The occupational health volunteers trained in 2008 were farmers, beauty salon workers and doll makers. The occupational health and safety knowledge is extended to a new informal worker group: sweet-crispy fish producer, in 2009. The occupational health and safety training for sweet-crispy fish group is conducted by occupational health volunteers. The occupational health volunteers increased their skills and knowledge assist in to make safe home and safe community through participatory oriented training. The improvement of living and working condition is conducted by using a modified WISH, Work Improvement for Safe Home, checklist. The plans of improvement were recorded. The informal workers showed improvement mostly on material handling and storage. The safe uses and safe

  15. Image-Guided Transvesicular Drainage of Pelvic Fluid Collections: A Safe and Effective Alternative Approach.

    Science.gov (United States)

    Ayyagari, Raj R; Yeh, Cliff; Arici, Melih; Mojibian, Hamid; Reiner, Eric; Pollak, Jeffrey S

    2016-05-01

    To evaluate the safety and efficacy of percutaneous transvesicular drainage of pathologic pelvic fluid collections, a series of 15 patients who underwent 16 transvesicular drainage catheter placements was retrospectively reviewed. All patients had collections suspicious for infection that were posterior to the bladder or superior to the bladder behind loops of bowel, and were otherwise inaccessible. All 15 collections were percutaneously accessed via the bladder with standard drainage catheters. All collections resolved completely with no complications. Percutaneous transvesicular drainage was a safe and effective technique in this series, and can be considered when no direct percutaneous access routes are available. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

  16. Safe use of nanomaterials

    CERN Multimedia

    2013-01-01

    The use of nanomaterials  is on the increase worldwide, including at CERN. The HSE Unit has established a safety guideline to inform you of the main requirements for the safe handling and disposal of nanomaterials at CERN.   A risk assessment tool has also been developed which guides the user through the process of evaluating the risk for his or her activity. Based on the calculated risk level, the tool provides a list of recommended control measures.   We would therefore like to draw your attention to: Safety Guideline C-0-0-5 - Safe handling and disposal of nanomaterials; and Safety Form C-0-0-2 - Nanomaterial Risk Assessment   You can consult all of CERN’s safety rules and guidelines here. Please contact the HSE Unit for any questions you may have.   The HSE Unit

  17. Plutonium safe handling

    International Nuclear Information System (INIS)

    Tvehlov, Yu.

    2000-01-01

    The abstract, prepared on the basis of materials of the IAEA new leadership on the plutonium safe handling and its storage (the publication no. 9 in the Safety Reports Series), aimed at presenting internationally acknowledged criteria on the radiation danger evaluation and summarizing the experience in the safe management of great quantities of plutonium, accumulated in the nuclear states, is presented. The data on the weapon-class and civil plutonium, the degree of its danger, the measures for provision of its safety, including the data on accident radiation consequences with the fission number 10 18 , are presented. The recommendations, making it possible to eliminate the super- criticality danger, as well as ignition and explosion, to maintain the tightness of the facility, aimed at excluding the radioactive contamination and the possibility of internal irradiation, to provide for the plutonium security, physical protection and to reduce irradiation are given [ru

  18. Comparison of F-18 FDG PET and I-131 whole body scan in diagnosis of suspicious metastatic thyroid carcinoma

    International Nuclear Information System (INIS)

    Seok, Ju Won; Chung, June Key

    2005-01-01

    There are several reports about the usefulness of F-18 FDG PET in thyroid cancer. The aim of this study was to evaluate the effectiveness of F-18 FDG PET and I-131 whole body scan in suspicious metastatic thyroid cancer. There were 46 patients (11 men, 35 women; age range, 18-74yr; mean age, 47.3yr) with suspicious metastatic thyroid cancer after total thyroidectomy who performed FDG PET and I-131 scan. The interval of FDG PET and I-131 scan was within 6 months. An overall clinical evaluation was performed including cytology, thyroglobulin level, sonography, MRI and CT. Metastatic regions were divided into four areas: neck, mediastinum, lung and bone. Among 46 patients, the number of patients, metastatic lesions were detected, totaled 36 (78.3%). Twenty-nine patients (63.0%) were detected by FDG PET and 18 patients (39.1%) were detected by I-131 scan. Twenty-one patients were detected in neck by two methods. Nineteen patients (90.5%) were detected by FDG PET and 7 patients (33.3%) were detected by I-131 scan. Eighteen patients were detected in mediastinum by two methods. Ten patients (55.5%) were detected by FDG PET and 10 patients (55.5%) were detected by I-131 scan. Ten patients were detected in lung by two methods. Nine patients (90.0%) were detected by FDG PET and 3 patients (30.0%) were detected by I-131 scan. Three patients were detected in bone by two methods. Three patients (100%) were detected by FDG PET and 0 patients (0%) were detected by I-131 scan. These data indicate that for detecting metastatic lesions, F-18 FDG PET and I-131 whole body scan may provide complementary information. Thus, the combination of FDG PET and I-131 scan is the method of choice for detecting suspicious metastatic thyroid cancer after total thyroidectomy

  19. [How safe are nanoparticles?].

    Science.gov (United States)

    Lademann, J; Meinke, M; Sterry, W; Patzelt, A

    2009-04-01

    Nanoparticles are experiencing an increasing application in dermatology and cosmetics. In both application areas, the requirements of nanoparticles are in most cases widely different. As a component of sunscreens, the nanoparticles are supposed to remain on the skin surface or in the upper most layers of the stratum corneum to protect the skin against UV-radiation of the sun. Whereas, on the other hand, when particulate substances are used as carrier systems for drugs, they have to cross the skin barrier to reach the target sites within the living tissue. We discuss the perspectives and risks of the topical application of nanoparticles.

  20. Escola segura Safe school

    Directory of Open Access Journals (Sweden)

    Edson Ferreira Liberal

    2005-11-01

    Full Text Available OBJETIVO: Revisão das estratégias para tornar o ambiente escolar seguro. Inicialmente os autores contextualizam a violência e os acidentes no ambiente escolar e fazem recomendações, baseadas em dados da literatura, para a implantação de escolas seguras. FONTE DE DADOS: Artigos publicados entre 1993 e 2005 na base de dados MEDLINE. Dados nacionais epidemiológicos e da literatura também foram pesquisados. SÍNTESE DOS DADOS: Há evidência crescente de que a intervenção tem múltiplos componentes. O foco político é a prática em educação em saúde com o envolvimento de toda a comunidade. O norte dessas intervenções é ajudar estudantes e toda a comunidade a adotar um comportamento seguro e saudável. As escolas estão assumindo um envolvimento crescente na promoção da saúde, prevenção de doenças e prevenção de trauma. Nesse contexto de prevenção de causas externas de morbimortalidade, é importante reconhecer o risco ambiental, locais e comportamentos de risco como favoráveis ao trauma e à violência, além de um novo conceito de acidentes como algo que possa ser evitado. CONCLUSÃO: A implementação da escola segura representa uma nova direção promissora para o trabalho preventivo baseado na escola. É importante notar que uma escola segura deve intervir não meramente na sua estrutura física, mas também torná-la tão segura quanto possível, trabalhando com a comunidade escolar por meio de educação em saúde, discutindo principalmente o comportamento saudável.OBJECTIVE: To review the strategies to make school a safe environment. The paper first addresses the social context of accidents and violence in the school environment, and makes recommendations, based on the literature data, for the implementation of safe schools. SOURCE OF DATA: Articles published between 1993 and 2005 in the MEDLINE database. Brazilian epidemiological and literature data have also been searched. SUMMARY OF THE FINDINGS: There is

  1. Safe motherhood at risk?

    Science.gov (United States)

    Thompson, A

    1996-12-01

    Health professionals' negative attitudes toward clients often exacerbate the problems women face in terms of health status and access to health care. Thus, the health professionals can themselves be obstacles to women seeking the health care they need. A key challenge to midwives, in addition to providing technically competent services, is gaining insight into the people for whom they are responsible so that childbirth traditions are treated with respect and women are offered dignity. Safe motherhood requires intersectoral collaboration. Many innovative approaches to safe motherhood are based on the community's participation in planning services that meet the needs of women. Other approaches are based on decentralization of services. For example, a large university teaching hospital in Lusaka, Zambia, set up birthing centers around the city to take the pressure off the hospital. Midwives head up these centers, which are close to the women's homes. Decentralization of delivery services has improved the physical and emotional outcomes for mothers and newborns. Midwives must be prepared to articulate concerns about inequalities and deficiencies in the health care system in order to persuade the government to change. Women, including midwives, need to form multidisciplinary alliances to work together to effect change. The front-line workers in maternity care are midwives. They should adopt the following strategies to become even more effective in their efforts to make motherhood safer. They should listen to what women say about their needs. They should scale services to a manageable, human scale. They should learn the skills to become politically active advocates. They should work with other midwives, women, leaders, and other professional groups. Motherhood can be safe when women have more control over their own decision making, the education to liberate themselves to make their own decisions, and access to skilled care.

  2. Inherently safe reactors

    International Nuclear Information System (INIS)

    Maartensson, Anders

    1992-01-01

    A rethinking of nuclear reactor safety has created proposals for new designs based on inherent and passive safety principles. Diverging interpretations of these concepts can be found. This article reviews the key features of proposed advanced power reactors. An evaluation is made of the degree of inherent safety for four different designs: the AP-600, the PIUS, the MHTGR and the PRISM. The inherent hazards of today's most common reactor principles are used as reference for the evaluation. It is concluded that claims for the new designs being inherently, naturally or passively safe are not substantiated by experience. (author)

  3. Can positron emission mammography help to identify clinically significant breast cancer in women with suspicious calcifications on mammography?

    Energy Technology Data Exchange (ETDEWEB)

    Bitencourt, Almir G.V.; Lima, Eduardo N.P.; Macedo, Bruna R.C.; Conrado, Jorge L.F.A.; Marques, Elvira F.; Chojniak, Rubens [A C Camargo Cancer Center-Department of Imaging, Sao Paulo, SP (Brazil)

    2017-05-15

    To evaluate the diagnostic accuracy of positron emission mammography (PEM) for identifying malignant lesions in patients with suspicious microcalcifications detected on mammography. A prospective, single-centre study that evaluated 40 patients with suspicious calcifications at mammography and indication for percutaneous or surgical biopsy, with mean age of 56.4 years (range: 28-81 years). Patients who agreed to participate in the study underwent PEM with 18F-fluorodeoxyglucose before the final histological evaluation. PEM findings were compared with mammography and histological findings. Most calcifications (n = 34; 85.0 %) were classified as BIRADS 4. On histology, there were 25 (62.5 %) benign and 15 (37.5 %) malignant lesions, including 11 (27.5 %) ductal carcinoma in situ (DCIS) and 4 (10 %) invasive carcinomas. On subjective analysis, PEM was positive in 15 cases (37.5 %) and most of these cases (n = 14; 93.3 %) were confirmed as malignant on histology. There was one false-positive result, which corresponded to a fibroadenoma, and one false negative, which corresponded to an intermediate-grade DCIS. PEM had a sensitivity of 93.3 %, specificity of 96.0 % and accuracy of 95 %. PEM was able to identify all invasive carcinomas and high-grade DCIS (nuclear grade 3) in the presented sample, suggesting that this method may be useful for further evaluation of patients with suspected microcalcifications. (orig.)

  4. A comparisonof lymphocytic thyroiditis with papillary thyroid carcinoma showing suspicious ultrasonographic findings in a background of heterogeneous parenchyma

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Sang Yu; Shin, Jung Hee; Ko, Eun Young; Hahn, Soo Yeon [Dept. of Radiology, Samsung Medicine Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2015-01-15

    The aim of this study was to compare ultrasonographic features in patients with lymphocytic thyroiditis (LT) and papillary thyroid carcinoma (PTC) having suspicious thyroid nodule(s) in a background of heterogeneous parenchyma and to determine the clinical and radiological predictors of malignancy. We reviewed the cases of 100 patients who underwent ultrasonography between April 2011 and October 2012, and showed suspicious thyroid nodule(s) in a background of heterogeneous parenchyma. Eight patients who did not undergo ultrasonography-guided fineneedle aspiration cytology (FNAC) and 34 cases of follow-up ultrasonography after initial FNAC were excluded. We compared the benign and malignant nodules in terms of their clinical and radiological factors. For the 58 nodules including 31 LTs (53.4%) and 27 PTCs (46.6%), the mean tumor sizes of the two groups were 0.96 cm for LT and 0.97 cm for PTC. A univariate analysis revealed that PTCs were more frequent in patients younger than 45 years and having microcalcifications than was LT. An independent predictor of PTC after adjustment was an age of <45 years. LT mimics malignancy in a background of heterogeneous parenchyma on ultrasonography. A young age of <45 years is the most important predictor of malignancy in this condition.

  5. Safe handling of tritium

    International Nuclear Information System (INIS)

    1991-01-01

    The main objective of this publication is to provide practical guidance and recommendations on operational radiation protection aspects related to the safe handling of tritium in laboratories, industrial-scale nuclear facilities such as heavy-water reactors, tritium removal plants and fission fuel reprocessing plants, and facilities for manufacturing commercial tritium-containing devices and radiochemicals. The requirements of nuclear fusion reactors are not addressed specifically, since there is as yet no tritium handling experience with them. However, much of the material covered is expected to be relevant to them as well. Annex III briefly addresses problems in the comparatively small-scale use of tritium at universities, medical research centres and similar establishments. However, the main subject of this publication is the handling of larger quantities of tritium. Operational aspects include designing for tritium safety, safe handling practice, the selection of tritium-compatible materials and equipment, exposure assessment, monitoring, contamination control and the design and use of personal protective equipment. This publication does not address the technologies involved in tritium control and cleanup of effluents, tritium removal, or immobilization and disposal of tritium wastes, nor does it address the environmental behaviour of tritium. Refs, figs and tabs

  6. Vitamins, Are They Safe?

    Directory of Open Access Journals (Sweden)

    Hadi Hamishehkar

    2016-12-01

    Full Text Available The consumption of a daily multivitamin among people all over the world is dramatically increasing in recent years. Most of the people believe that if vitamins are not effective, at least they are safe. However, the long term health consequences of vitamins consumption are unknown. This study aimed to assess the side effects and possible harmful and detrimental properties of vitamins and to discuss whether vitamins can be used as safe health products or dietary supplements. We performed a MEDLINE/PubMed, EMBASE, Scopus and Google Scholar search and assessed reference lists of the included studies which were published from 1993 through 2015. The studies, with an emphasis on RCTs (randomized controlled clinical trials, were reviewed. As some vitamins such as fat-soluble vitamins (vitamin A, vitamin D, vitamin E, and also some of the water-soluble vitamins like folic acid may cause adverse events and some like vitamin C is widely taken assuming that it has so many benefits and no harm, we included relevant studies with negative or undesired results regarding the effect of these vitamins on health. Our recommendation is that taking high-dose supplements of vitamins A, E, D, C, and folic acid is not always effective for prevention of disease, and it can even be harmful to the health.

  7. Cool and Safe: Multiplicity in Safe Innovation at Unilever

    Science.gov (United States)

    Penders, Bart

    2011-01-01

    This article presents the making of a safe innovation: the application of ice structuring protein (ISP) in edible ices. It argues that safety is not the absence of risk but is an active accomplishment; innovations are not "made safe afterward" but "safe innovations are made". Furthermore, there are multiple safeties to be accomplished in the…

  8. 21 CFR 178.3010 - Adjuvant substances used in the manufacture of foamed plastics.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Adjuvant substances used in the manufacture of... substances used in the manufacture of foamed plastics. The following substances may be safely used as adjuvants in the manufacture of foamed plastics intended for use in contact with food, subject to any...

  9. Safe pill-dispensing.

    Science.gov (United States)

    Testa, Massimiliano; Pollard, John

    2007-01-01

    Each patient is supplied with a smart-card containing a Radio Frequency IDentification (RFID) chip storing a unique identification code. The patient places the Smart-card on a pill-dispenser unit containing an RFID reader. The RFID chip is read and the code sent to a Base-station via a wireless Bluetooth link. A database containing both patient details and treatment information is queried at the Base-station using the RFID as the search key. The patient's treatment data (i.e., drug names, quantities, time, etc.) are retrieved and sent back to the pill-dispenser unit via Bluetooth. Appropriate quantities of the required medications are automatically dispensed, unless the patient has already taken his/her daily dose. Safe, confidential communication and operation is ensured.

  10. A safe workplace

    International Nuclear Information System (INIS)

    Rittsel, Hans; Andersson, Bengt A.

    1993-01-01

    Full text: The video 'A safe workplace' has been produced by ABB Atom in order to create a tool for showing different target audiences that ABB Atom Nuclear Fuel Production Plant is a safe workplace and to 'de-mystify' nuclear fuel production. The main target audiences are visitor groups and employees of the company, but the video also qualifies for use as an information tool for other target groups who ask for a proper explanation of the way nuclear fuel is produced. The summarized content of the video is as follows: All individual steps of the production process are described with focus on the safety, quality and environmental requirements. The first part shows the delivery of UF 6 (uranium hexafluoride) to the plant and the following process for the conversion to UO 2 (uranium dioxide). The conversion method used is wet conversion that includes evaporation, precipitation, filtration, washing, reduction and stabilization. The next part is a description of the fuel pellet manufacture including uranium oxide blending, pellet pressing, sintering, grinding and a final visual inspection. A separate part, describing the manufacture of fuel pellets with a burnable neutron absorber, is included. The third part shows how to produce fuel rods and complete assemblies. Some of the moments of quality supervision that support the entire manufacturing process are also shown. The last part of the video comprises a brief description of the manufacture of fuel channels and other reactor core components like control rods. The video is produced with a Swedish spoken narrative. The playing time is 15 minutes. The video will be delivered with a text printed in English and copies reproduced in the PAL/VHS system may be ordered from ABB Atom Communication Dept. telefax no +4621-11 41 90, at the price of USD 100.- or SEK 750.- each. (author)

  11. Strategies for safe motherhood.

    Science.gov (United States)

    Chatterjee, A

    1995-02-01

    The Safe Motherhood Initiative was launched in 1988 as a global effort to halve maternal mortality and morbidity by the year 2000. The program uses a combination of health and nonhealth strategies to emphasize the need for maternal health services, extend family planning services, and improve the status of women. The maternal mortality rate (per 100,000 live births) is 390 for the world, 20-30 for developed countries, 450 for developing countries, and 420 for Asia. This translates into 308,000 maternal deaths in Asia, of which 100,000 occur in India. The direct causes of maternal mortality include sepsis, hemorrhage, eclampsia, and ruptured uterus. Indirect causes occur when associated medical conditions, such as anemia and jaundice, are exacerbated by pregnancy. Underlying causes are ineffective health services, inadequate obstetric care, unregulated fertility, infections, illiteracy, early marriage, poverty, malnutrition, and ignorance. India's Child Survival and Safe Motherhood Program seeks to achieve immediate improvements by improving health care. Longterm improvements will occur as nutrition, income, education, and the status of women improve. Improvements in health care will occur in through the provision of 1) essential obstetric care for all women (which will be essentially designed for low-risk women), 2) early detection of complications during pregnancy and labor, and 3) emergency services. Services will be provided to pregnant women at their door by field staff, at a first referral hospital, perhaps at maternity villages where high risk cases can be housed in the latter part of their pregnancies, and through the continual accessibility of government vehicles. In addition, family planning services will be improved so that fertility regulation can have its expected beneficial effect on the maternal mortality rate. The professional health organizations in India will also play a vital role in the success of this effort to reduce maternal mortality.

  12. TSCA Chemical Substance Inventory

    Science.gov (United States)

    Section 8 (b) of the Toxic Substances Control Act (TSCA) requires EPA to compile, keep current, and publish a list of each chemical substance that is manufactured or processed in the United States for TSCA uses.

  13. Safe percutaneous suprapubic catheterisation.

    Science.gov (United States)

    Goyal, N K; Goel, A; Sankhwar, S N

    2012-11-01

    We describe our technique of percutaneous suprapubic catheter insertion with special reference to steps that help to avoid common complications of haematuria and catheter misplacement. The procedure is performed using a stainless steel reusable trocar under local infiltrative anaesthesia, usually at the bedside. After clinical confirmation of a full bladder, the trocar is advanced into the bladder through a skin incision. Once the bladder is entered, the obturator is removed and the assistant inserts a Foley catheter followed by rapid balloon inflation. Slight traction is applied to the catheter for about five minutes. Patients with previous lower abdominal surgery, an inadequately distended bladder or acute pelvic trauma do not undergo suprapubic catheterisation using this method. The procedure was performed in 72 men (mean age: 42.4 years, range: 18-78 years) with urinary retention with a palpable bladder. The average duration of the procedure was less than five minutes. No complications were noted in any of the patients. Trocar suprapubic catheter insertion is a safe and effective bedside procedure for emergency bladder drainage and can be performed by resident surgeons. The common complications associated with the procedure can be avoided with a few careful steps.

  14. Making Our Food Safe

    International Nuclear Information System (INIS)

    Madsen, Michael

    2013-01-01

    Full text: As civilization has progressed societies have strived to make food safer; from using fire to cook our food, and boiling our water to make it safe to drink, advances in technology have helped kill microorganisms that can make food unsafe. The FAO/IAEA Joint Division helps provide technical assistance to Member States that want to implement irradiation technology in making their food safer. Food and waterborne diarrhoeal diseases are estimated to kill roughly 2.2 million people annually, of which 1.9 million are children. Irradiating some of the foods we eat can save many of these lives by reducing the risk of food poisoning and killing the organisms that cause disease. Irradiation works by treating food with a small dose of ionizing radiation, this radiation disrupts the bacteria’s DNA and cell membranes structure stopping the organism from reproducing or functioning, but does not make the food radioactive. It can be applied to a variety of foods from spices and seasonings, to fruits and vegetables and is similar to pasteurization, but without the need for high temperatures that might impair food quality. (author)

  15. OPINION: Safe exponential manufacturing

    Science.gov (United States)

    Phoenix, Chris; Drexler, Eric

    2004-08-01

    In 1959, Richard Feynman pointed out that nanometre-scale machines could be built and operated, and that the precision inherent in molecular construction would make it easy to build multiple identical copies. This raised the possibility of exponential manufacturing, in which production systems could rapidly and cheaply increase their productive capacity, which in turn suggested the possibility of destructive runaway self-replication. Early proposals for artificial nanomachinery focused on small self-replicating machines, discussing their potential productivity and their potential destructiveness if abused. In the light of controversy regarding scenarios based on runaway replication (so-called 'grey goo'), a review of current thinking regarding nanotechnology-based manufacturing is in order. Nanotechnology-based fabrication can be thoroughly non-biological and inherently safe: such systems need have no ability to move about, use natural resources, or undergo incremental mutation. Moreover, self-replication is unnecessary: the development and use of highly productive systems of nanomachinery (nanofactories) need not involve the construction of autonomous self-replicating nanomachines. Accordingly, the construction of anything resembling a dangerous self-replicating nanomachine can and should be prohibited. Although advanced nanotechnologies could (with great difficulty and little incentive) be used to build such devices, other concerns present greater problems. Since weapon systems will be both easier to build and more likely to draw investment, the potential for dangerous systems is best considered in the context of military competition and arms control.

  16. Aflatoxins & Safe Storage

    Directory of Open Access Journals (Sweden)

    Philippe eVillers

    2014-04-01

    Full Text Available The paper examines both field experience and research on the prevention of the exponential growth of aflatoxins during multi-month post harvest storage in hot, humid countries. The approach described is the application of modern safe storage methods using flexible, Ultra Hermetic™ structures that create an unbreatheable atmosphere through insect and microorganism respiration alone, without use of chemicals, fumigants, or pumps. Laboratory and field data are cited and specific examples are given describing the uses of Ultra Hermetic storage to prevent the growth of aflatoxins with their significant public health consequences. Also discussed is the presently limited quantitative information on the relative occurrence of excessive levels of aflatoxin (>20 ppb before versus after multi-month storage of such crops as maize, rice and peanuts when under high humidity, high temperature conditions and, consequently, the need for further research to determine the frequency at which excessive aflatoxin levels are reached in the field versus after months of post-harvest storage. The significant work being done to reduce aflatoxin levels in the field is mentioned, as well as its probable implications on post harvest storage. Also described is why, with some crops such as peanuts, using Ultra Hermetic storage may require injection of carbon dioxide or use of an oxygen absorber as an accelerant. The case of peanuts is discussed and experimental data is described.

  17. The added value of contrast enhanced spectral mammography in identification of multiplicity of suspicious lesions in dense breast

    Directory of Open Access Journals (Sweden)

    Amr Farouk Ibrahim Moustafa

    2018-03-01

    Full Text Available Objective: To evaluate the additive value of Contrast Enhanced Spectral Mammography (CESM in the preoperative assessment of malignant lesions in dense breast parenchyma regarding multiplicity. Material and methods: The study included 160 women having heterogeneous dense breast parenchyma (ACR c and d with suspicious lesions identified on sono mammography examination. All patients performed contrast enhanced spectral mammography to confirm or exclude lesion multiplicity. The number of lesions was calculated in the contrast high energy subtraction images with the reference standard being histopathological analysis. Results: Adding CESM to sono-mammography the accuracy in identifying multiple malignant lesion increased from 81.8% accuracy of sono-mammography up to 100% accuracy after adding CESM. Conclusion: Contrast enhanced spectral mammogram showed an added value in the preoperative assessment of breast masses increasing the accuracy of detection of lesions and multiplicity (multifocality and multi-centricity. Keywords: Breast cancer, Contrast enhanced spectral mammogram

  18. The clinical value of bilateral breast MR imaging: is it worth performing on patients showing suspicious microcalcifications on mammography?

    Energy Technology Data Exchange (ETDEWEB)

    Akita, Ayano; Tanimoto, Akihiro; Kuribayashi, Sachio [Keio University, Department of Diagnostic Radiology, School of Medicine, Tokyo (Japan); Jinno, Hiromitsu [Keio University, Department of Surgery, School of Medicine, Tokyo (Japan); Kameyama, Kaori [Keio University, Division of Diagnostic Pathology, School of Medicine, Tokyo (Japan)

    2009-09-15

    The purpose of this study was to evaluate the clinical value of bilateral breast magnetic resonance (MR) imaging (MRI) in patients showing suspicious microcalcifications on mammography and negative ultrasound findings. Fifty patients underwent MRI before stereotactic vacuum-assisted breast biopsy (SVAB). MR findings were classified into five types for interpretation, and types 4 and 5 were considered malignant. SVAB revealed 13 carcinomas and 37 benign lesions. Malignant lesions were more frequently found in cases of positive MRI diagnoses than in negative MRI diagnoses (P < 0.001). Mammography had a sensitivity of 100%, a specificity of 24% and an accuracy of 44%, whereas mammography plus MRI had a sensitivity of 85%, a specificity of 100% and an accuracy of 96%. In the evaluation of mammographically detected microcalcifications, bilateral breast MRI is of good diagnostic value and may alter the indications for SVAB. (orig.)

  19. Anxiety/Depression and Hostility/Suspiciousness in Adolescent Boys: Testing Adherence to Honor Code as Mediator of Callousness and Attachment Insecurity

    Science.gov (United States)

    Somech, Lior Y.; Elizur, Yoel

    2012-01-01

    Research of psychological distress (PD) needs to differentiate between anxiety/depression and hostility/suspiciousness, which are associated with different motivational systems. In this study, structural equation modeling was used to test two hypothesized models for the prediction of each facet of PD. Hypotheses were proposed about the effects of…

  20. SAFE Journal. Volume 35, Number 1, Spring 2007

    Science.gov (United States)

    2007-01-01

    Division Eye Tactical, Inc. - Sales and Marketing Division First Technology Safety Systems, Inc. Fujikura Parachute Co., Ltd. FXC Corporation... markets for environmentally friendly products. The E.PA is considering using Section 6 of the Toxic Substances Control Act (TSCA) to regulate...CH,OH 0,N SAFE Journal - Vol 35(1) - Spring 2007 15 RESEARC H, DEVELOPMENT. TEST & EVALUATION SECTION Figure 2. Preparation of KDNP (1) using a

  1. Detection of suspicious malignant cervical lymph nodes of unknown origin: diagnostic accuracy of ultrasound-guided fine-needle aspiration biopsy with nodal size and central necrosis correlate

    International Nuclear Information System (INIS)

    Lo, C.-P.; Chen, C.-Y.; Chin, S-.C.; Lee, K.-W.; Hsueh, C.-J.; Juan, C.-J.; Kao, H.-W.; Huang, G.-S.

    2007-01-01

    To assess the role of ultrasound-guided fine-needle aspiration biopsy (US-guided FNAB) in the diagnostic workup of suspicious malignant cervical lymph nodes in patients with palpable neck masses and without known primary cancer. The diagnostic accuracy of imaging morphologic criteria, including sizes and central necrosis for assessing suspicious malignant nodes, were also examined. This is a retrospective study of 426 patients with palpable neck masses from an outpatient department evaluated with computed tomography, magnetic resonance imaging, or US. US-guided FNABs were performed in 102 patients with suspicious malignant cervical lymph nodes at a single institution. Cytologically positive lymph nodes (n = 12) were further validated with excisional biopsy. Negative lymph nodes (n = 90) were either excised (n = 10) or followed up by imaging studies for at least one year (n = 80). The diagnostic accuracy of the FNABs along with the imaging findings of nodal sizes and presence of central necrosis, which were classified by a consensus of 2 radiologists, were assessed. Twelve malignant nodes were detected with US-guided FNAB with one false-positive and one false-negative result. The overall sensitivity, specificity, and accuracy for FNAB were 91.7%, 98.9%, and 98.0%. respectively. The sensitivity, specificity, and accuracy were 66.7%, 30.0%, and 34.3% for size criterion and 75.0%, 83.3%, and 82.3% for central necrosis criterion. The size of cervical lymph node does not appear to be an important imaging criterion for assessing suspicious malignant lymph nodes, compared with the criterion of central necrosis. US-guided FNAB is highly specific and sensitive in the diagnostic workup of suspicious malignant cervical lymph nodes in patients without known primary cancers. (author)

  2. Safe Minimum Internal Temperature Chart

    Science.gov (United States)

    ... Internal Temperature Chart Safe steps in food handling, cooking, and storage are essential in preventing foodborne illness. You can't see, smell, or taste harmful bacteria that may cause illness. In every step of food preparation, follow the four guidelines to keep food safe: ...

  3. More than a Safe Space

    Science.gov (United States)

    Sadowski, Michael

    2016-01-01

    Over the past three decades, much of the conversation about LGBTQ students in schools has centered on safety--anti-bullying policies, the "safe space" of gay-straight alliances, and "safe zones" marked by rainbow-colored stickers on classroom doors. In this article, Michael Sadowski argues that it's time to move beyond safety…

  4. Staying Safe in the Water

    Centers for Disease Control (CDC) Podcasts

    In this podcast, Dr. Julie Gilchrist, a pediatrician and medical epidemiologist from CDC’s Injury Center, talks about staying safe in the water. Tips are for all audiences, with a focus on preventing drownings and keeping children safe in and around the pool, lake, or ocean.

  5. Substance use - cocaine

    Science.gov (United States)

    Substance abuse - cocaine; Drug abuse - cocaine; Drug use - cocaine ... thinking clearly Mood and emotional problems, such as aggressive or violent behavior Restlessness and tremors Sleep problems ...

  6. Substance use - phencyclidine (PCP)

    Science.gov (United States)

    PCP; Substance abuse - phencyclidine; Drug abuse - phencyclidine; Drug use - phencyclidine ... a result, you may act strangely or become aggressive and violent. PCP's other harmful effects include: It ...

  7. Safe Anesthesia For Every Tot

    DEFF Research Database (Denmark)

    Weiss, Markus; Vutskits, Laszlo; Hansen, Tom G

    2015-01-01

    PURPOSE OF REVIEW: The term 'safe use of anesthesia in children is ill-defined and requires definition of and focus on the 'safe conduct of pediatric anesthesia'. RECENT FINDINGS: The Safe Anesthesia For Every Tot initiative (www.safetots.org) has been set up during the last year to focus...... on the safe conduct of pediatric anesthesia. This initiative aims to provide guidance on markers of quality anesthesia care. The introduction and implementation of national regulations of 'who, where, when and how' are required and will result in an improved perioperative outcome in vulnerable children....... The improvement of teaching, training, education and supervision of the safe conduct of pediatric anesthesia are the main goals of the safetots.org initiative. SUMMARY: This initiative addresses the well known perioperative risks in young children, perioperative causes for cerebral morbidity as well as gaps...

  8. Stormram 4: An MR Safe Robotic System for Breast Biopsy.

    Science.gov (United States)

    Groenhuis, Vincent; Siepel, Françoise J; Veltman, Jeroen; van Zandwijk, Jordy K; Stramigioli, Stefano

    2018-05-21

    Suspicious lesions in the breast that are only visible on magnetic resonance imaging (MRI) need to be biopsied under MR guidance with high accuracy and efficiency for accurate diagnosis. The aim of this study is to present a novel robotic system, the Stormram 4, and to perform preclinical tests in an MRI environment. Excluding racks and needle, its dimensions are 72 × 51 × 40 mm. The Stormram 4 is driven by two linear and two curved pneumatic stepper motors. The linear motor is capable of exerting 63 N of force at a pressure of 0.65 MPa. In an MRI environment the maximum observed stepping frequency is 30 Hz (unloaded), or 8 Hz when full force is needed. The Stormram 4's mean positioning error is 0.73 ± 0.47 mm in free air, and 1.29 ± 0.59 mm when targeting breast phantoms in MRI. Excluding the off-the-shelf needle, the robot is inherently MR safe. The robot is able to accurately target lesions under MRI guidance, reducing tissue damage and risk of false negatives. These results are promising for clinical experiments, improving the quality of healthcare in the field of MRI-guided breast biopsies.

  9. Radioactive Substances Act 1948

    International Nuclear Information System (INIS)

    1948-01-01

    This Act regulates the use of radioactive substances and radiation producing devices in the United Kingdom. It provides for the control of import, export, sale, supply etc. of such substances and devices and lays down the safety regulations to be complied with when dealing with them. (NEA) [fr

  10. Transport of radioactive substances

    International Nuclear Information System (INIS)

    2014-12-01

    The report on the transport of radioactive substances covers the following topics: facts on radioactive materials transport, safety of the transport of radioactive substances, legal regulations and guidelines: a multiform but consistent system, transport of nuclear fuels, safety during the transport of nuclear fuel, future transport of spent fuel elements and high-level radioactive wastes in Germany.

  11. International conference on safe decommissioning for nuclear activities: Assuring the safe termination of practices involving radioactive materials. Contributed papers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    Thousands of operations involving the use of radioactive substances will end during the current century. While there is considerable regulatory experience in the 'front end' of the regulatory system for practices, the experience at the back end is more limited as fewer practices have actually been terminated. When a practice is terminated because the facility has reached the end of its useful life, action has to betaken to ensure the safe shutdown of the facility and allow the removal of regulatory controls. There are many issues involved in the safe termination of practices. These include setting criteria for the release of material and sites from regulatory control; determining the suitability of the various options for decommissioning nuclear facilities, managing the waste and material released from control (recycling, reuse or disposal), and the eventual remediation of the site. Some countries have put in place regulatory infrastructures and have developed programmes to manage the associated decommissioning and remediation activities. Other countries are at the stage of assessing what is involved in terminating such practices. The purpose of this Conference is to foster an information exchange on the safe an orderly termination of practices that involve the use of radioactive substances, including both decommissioning and environmental remediation, and to promote improved coherence internationally on strategies and criteria for the safe termination of practices.

  12. International conference on safe decommissioning for nuclear activities: Assuring the safe termination of practices involving radioactive materials. Contributed papers

    International Nuclear Information System (INIS)

    2002-01-01

    Thousands of operations involving the use of radioactive substances will end during the current century. While there is considerable regulatory experience in the 'front end' of the regulatory system for practices, the experience at the back end is more limited as fewer practices have actually been terminated. When a practice is terminated because the facility has reached the end of its useful life, action has to betaken to ensure the safe shutdown of the facility and allow the removal of regulatory controls. There are many issues involved in the safe termination of practices. These include setting criteria for the release of material and sites from regulatory control; determining the suitability of the various options for decommissioning nuclear facilities, managing the waste and material released from control (recycling, reuse or disposal), and the eventual remediation of the site. Some countries have put in place regulatory infrastructures and have developed programmes to manage the associated decommissioning and remediation activities. Other countries are at the stage of assessing what is involved in terminating such practices. The purpose of this Conference is to foster an information exchange on the safe an orderly termination of practices that involve the use of radioactive substances, including both decommissioning and environmental remediation, and to promote improved coherence internationally on strategies and criteria for the safe termination of practices

  13. Indoor Tanning Is Not Safe

    Science.gov (United States)

    ... the sun is by using these tips for skin cancer prevention. Indoor tanning is not a safe way to get vitamin ... to previous findings on the association between indoor tanning and skin cancer. Only a small number of people reported ...

  14. Alcohol use and safe drinking

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/001944.htm Alcohol use and safe drinking To use the sharing features on this page, please enable JavaScript. Alcohol use involves drinking beer, wine, or hard liquor. ...

  15. Dukovany NPP - Safely 16 TERA

    International Nuclear Information System (INIS)

    Vlcek, J.

    2008-01-01

    In this presentation increasing of power output of the Dukovany NPP is reviewed. To operate all Dukovany Units safely with the perspective of long-term operation (LTO) of 50 - 60 years it is proposed.

  16. Safe drinking during cancer treatment

    Science.gov (United States)

    ... ency/patientinstructions/000060.htm Drinking water safely during cancer treatment To use the sharing features on this page, please enable JavaScript. During and right after your cancer treatment, your body may not be able to protect ...

  17. Safe handling of radiation sources

    International Nuclear Information System (INIS)

    Abd Nasir Ibrahim; Azali Muhammad; Ab Razak Hamzah; Abd Aziz Mohamed; Mohammad Pauzi Ismail

    2004-01-01

    This chapter discussed the subjects related to the safe handling of radiation sources: type of radiation sources, method of use: transport within premises, transport outside premises; Disposal of Gamma Sources

  18. Towards Safe Robotic Surgical Systems

    DEFF Research Database (Denmark)

    Sloth, Christoffer; Wisniewski, Rafael

    2015-01-01

    a controller for motion compensation in beating-heart surgery, and prove that it is safe, i.e., the surgical tool is kept within an allowable distance and orientation of the heart. We solve the problem by simultaneously finding a control law and a barrier function. The motion compensation system is simulated...... from several initial conditions to demonstrate that the designed control system is safe for every admissible initial condition....

  19. Safe use of ionizing radiations

    Energy Technology Data Exchange (ETDEWEB)

    1973-01-01

    Based on the ''Code of Practice for the protection of persons against ionizing radiations arising from medical and dental use'' (CIS 74-423), this handbook shows how hospital staff can avoid exposing themselves and others to these hazards. It is designed particularly for junior and student nurses. Contents: ionizing radiations, their types and characteristics; their uses and dangers; basic principles in their safe use; safe use in practice; explanation of terms.

  20. Staying Safe in the Water

    Centers for Disease Control (CDC) Podcasts

    2008-05-15

    In this podcast, Dr. Julie Gilchrist, a pediatrician and medical epidemiologist from CDC’s Injury Center, talks about staying safe in the water. Tips are for all audiences, with a focus on preventing drownings and keeping children safe in and around the pool, lake, or ocean.  Created: 5/15/2008 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 5/19/2008.

  1. Pricing hazardous substance emissions

    Energy Technology Data Exchange (ETDEWEB)

    Staring, Knut; Vennemo, Haakon

    1998-12-31

    This report discusses pricing of emissions to air of several harmful substances. It combines ranking indices for environmentally harmful substances with economic valuation data to yield price estimates. The ranking methods are discussed and a relative index established. Given the relative ranking of the substances, they all become valued by assigning a value to one of them, the `anchor` substance, for which lead is selected. Valuations are provided for 19 hazardous substances that are often subject to environmental regulations. They include dioxins, TBT, etc. The study concludes with a discussion of other categories of substances as well as uncertainties and possible refinements. When the valuations are related to CO, NOx, SOx and PM 10, the index system undervalues these pollutants as compared to other studies. The scope is limited to the outdoor environment and does not include global warming and eutrophication. The indices are based on toxicity and so do not apply to CO{sub 2} or other substances that are biologically harmless. The index values are not necessarily valid for all countries and should be considered as preliminary. 18 refs., 6 tabs.

  2. Pricing hazardous substance emissions

    Energy Technology Data Exchange (ETDEWEB)

    Staring, Knut; Vennemo, Haakon

    1997-12-31

    This report discusses pricing of emissions to air of several harmful substances. It combines ranking indices for environmentally harmful substances with economic valuation data to yield price estimates. The ranking methods are discussed and a relative index established. Given the relative ranking of the substances, they all become valued by assigning a value to one of them, the `anchor` substance, for which lead is selected. Valuations are provided for 19 hazardous substances that are often subject to environmental regulations. They include dioxins, TBT, etc. The study concludes with a discussion of other categories of substances as well as uncertainties and possible refinements. When the valuations are related to CO, NOx, SOx and PM 10, the index system undervalues these pollutants as compared to other studies. The scope is limited to the outdoor environment and does not include global warming and eutrophication. The indices are based on toxicity and so do not apply to CO{sub 2} or other substances that are biologically harmless. The index values are not necessarily valid for all countries and should be considered as preliminary. 18 refs., 6 tabs.

  3. [Immunotoxicity and environmental substances].

    Science.gov (United States)

    Teshima, Reiko

    2014-01-01

    A well functioning immune system is essential in maintaining integrity of the organism, and malfunction may have severe health consequences. Environmental substances may pose direct toxicity to components of the immune system, often leading to immunosuppression and resulting reduced resistance to infections and tumors. Alternatively, such substances may be recognized by the immune system in a specific fashion, which may result in allergy and autoimmunity. A proper risk assessment of environmental substances in terms of immunotoxicity is necessary. In this manuscript, I reviewed recent three topics about immunotoxicity: (1) IPCS/WHO Guidance for immunotoxicity risk assessment for chemicals, (2) Intestinal immunotoxicity, and (3) Epicutaneous sensitization of food proteins.

  4. Presence of histopathological premalignant lesions and infection caused by high-risk genotypes of human papillomavirus in patients with suspicious cytological and colposcopy results: A prospective study

    Directory of Open Access Journals (Sweden)

    Golubović Mileta

    2017-01-01

    Full Text Available Background/Aim. In patients with premalignant cervical lesions, human papillomavirus (HPV infection, at any moment, may be spontaneously eliminated, or may persist or transform cervical epithelium from a lower to a higher degree. Due to that, it is necessary to wisely select the patients who are at high risk of cancer development. The aim of the study was to establish the interdependence between a suspicious Papanicolaou (Pap test and colposcopy with the infection caused by high-risk genotypes of human papillomavirus and the presence of premalignant cervical lesions. Methods. This prospective study used cytological, colposcopy, real-time polymerase chain reaction (PCR of high-risk genotypes of human papillomavirus and histopathological analysis of cervical biopsy specimen. Out of 2,578 female patients sent to cytological analyses in Clinical Center of Montenegro, during 2012, 2013 and 2014, the study included 80 women who had to submit their biopsy specimens due to a suspicious Pap test and atypical colposcopy results. Results. In the group of 80 (3.1%; n = 80/2,578 of the selected female patients with suspicious Pap test and colposcopy, 2/3 or 56 (70% of them had cervicitis, and 1/3 or 24 (30% had cervical intraepithelial neoplasia. The most common type in cervical intraepithelial neoplasia was HPV16 in 8 female patients, ie 61.53% out of the number of infected, or 33.33% out of the total number of premalignant lesions. Conclusion. Patients with suspicious Papanicolaou test, colposcopy results and infection which is caused by high-risk HPV infection (HPV 16 in particular often have premalignant cervical lesions. In these cases, histopathological confirmation of lesions is mandatory, since it serves as a definitive diagnostic procedure.

  5. DOES FOOD SAFETY CONFLICT WITH FOOD SECURITY? THE SAFE CONSUMPTION OF FOOD

    OpenAIRE

    Kinsey, Jean D.

    2004-01-01

    This paper concludes by saying no, food safety and security reinforce each other. It combines food safety and food security into the concept of "safe food consumption." Unsafe food consumption occurs when food contains known substances that lead to short or long term illness or death (botulism) and suspect substances that are believed to lead to delayed diseases (pesticides). It also occurs when hunger or over eating contribute to long-term illness and shorter life expectancy. The costs of il...

  6. Subcategorization of Suspicious Breast Lesions (BI-RADS Category 4) According to MRI Criteria: Role of Dynamic Contrast-Enhanced and Diffusion-Weighted Imaging.

    Science.gov (United States)

    Maltez de Almeida, João Ricardo; Gomes, André Boechat; Barros, Thomas Pitangueira; Fahel, Paulo Eduardo; de Seixas Rocha, Mário

    2015-07-01

    The purposes of this study were to investigate whether dynamic contrast-enhanced MRI is adequate for subcategorization of suspicious lesions (BI-RADS category 4) and to evaluate whether use of DWI improves diagnostic performance. The study group was composed of 103 suspicious lesions found in 83 subjects. Patient ages and lesion sizes were compiled, and two radiologists reanalyzed the images; subcategorized the findings as BI-RADS 4A, 4B, or 4C; and calculated apparent diffusion coefficient (ADC) values. The stratified variables were tested by univariate analysis and inserted in two multivariate predictive models, which were used to generate ROC curves and compare AUCs. Positive predictive values (PPVs) for each subcategory and ADC level were calculated, and interobserver agreement was tested. Forty-four (42.7%) suspicious findings proved malignant. Except for age (p = 0.08), all stratified predictor variables were significant in univariate analyses (p BI-RADS 4 subcategory (4A, 0.15; 4B, 0.37; 4C, 0.84). ADC values of 1.10 × 10(-3) mm(2)/s or less had the second highest PPV (0.77). Interobserver agreement was substantial at a kappa value of 0.80 (95% CI, 0.70-0.90; p BI-RADS category 4) can be satisfactorily performed with DCE-MRI and slightly improved when DWI is introduced.

  7. EFFECT OF SUBSTANCE (1)

    African Journals Online (AJOL)

    OF HEALTH OFFICER AND MEDICAL STUDENTS OF JIMMA. UNIVERSITY ... cannabis or marihuana and khat (2, 3). Reports showed that these substances ... mainly through cancer especially lung cancer, of which about 90% of cases are ...

  8. Toxic substances handbook

    Science.gov (United States)

    Junod, T. L.

    1979-01-01

    Handbook, published in conjunction with Toxic Substances Alert Program at NASA Lewis Research Center, profiles 187 toxic chemicals in their relatively pure states and include 27 known or suspected carcinogens.

  9. Active substance from some blue green algal species used as ...

    African Journals Online (AJOL)

    The concept of biological control for health maintenance has received widespread attention during the last few years. Therefore, the main objective of this work was to look for active substances that could be used as antimicrobial agents in an efficient and safe manner. To achieve this target, five different extracts (ethyl ...

  10. Inherently safe light water reactors

    International Nuclear Information System (INIS)

    Ise, Takeharu

    1987-01-01

    Today's large nuclear power reactors of world-wise use have been designed based on the philosophy. It seems that recent less electricity demand rates, higher capital cost and the TMI accident let us acknowledge relative small and simplified nuclear plants with safer features, and that Chernobyl accident in 1983 underlines the needs of intrinsic and passive safety characteristics. In such background, several inherently safe reactor concepts have been presented abroad and domestically. First describing 'Can inherently safe reactors be designed,' then I introduce representative reactor concepts of inherently safe LWRs advocated abroad so far. All of these innovative reactors employ intrinsic and passive features in their design, as follows: (1) PIUS, an acronym for Process Inherent Ultimate Safety, or an integral PWR with passive heat sink and passive shutdown mechanism, advocated by ASEA-ATOM of Sweden. (2) MAP(Minimum Attention Plant), or a self-pressurized, natural circulation integral PWR, promoted by CE Inc. of the U.S. (3) TPS(TRIGA Power System), or a compact PWR with passive heat sink and inherent fuel characteristics of large prompt temperature coefficient, prompted by GA Technologies Inc. of the U.S. (4) PIUS-BWR, or an inherently safe BWR employing passively actuated fluid valves, in competition with PIUS, prompted by ORNL of the U.S. Then, I will describe the domestic trends in Japan and the innovative inherently safe LWRs presented domestically so far. (author)

  11. Qualitative and Semiquantitative Elastography for the Diagnosis of Intermediate Suspicious Thyroid Nodules Based on the 2015 American Thyroid Association Guidelines.

    Science.gov (United States)

    Yang, Bo Ra; Kim, Eun-Kyung; Moon, Hee Jung; Yoon, Jung Hyun; Park, Vivian Y; Kwak, Jin Young

    2018-04-01

    To evaluate qualitative and semiquantitative elastography for the diagnosis of intermediate suspicious thyroid nodules based on the 2015 American Thyroid Association (ATA) guidelines. Through a retrospective search of our institutional database, 746 solid thyroid nodules found on grayscale ultrasonography, strain elastography, and ultrasound-guided fine-needle aspiration between June and November 2009 were collected. Among them, 80 nodules from 80 patients with an intermediate suspicion of malignancy based on the 2015 ATA guidelines that were 10 mm or larger were recruited as the final study nodules. Elastographic findings were categorized according to the criteria of Rago et al (J Clin Endocrinol Metab 2007; 92:2917-2922) and Asteria et al (Thyroid 2008; 18:523-531), and strain ratio values were calculated and recorded. The independent 2-sample t test and χ 2 test (or Fisher exact test) were used to evaluate differences in clinical parameters between benign and malignant thyroid nodules. All variables were compared by univariate and multivariate logistic regression analyses, and odds ratios with 95% confidence intervals were calculated. Of the 80 nodules, 6 (7.5%) were malignant, and 74 (92.5%) were benign. No significant differences were observed in age, sex, nodule size, elasticity score, and strain ratio between benign and malignant nodules. No variables significantly predicted thyroid malignancy on the univariate analysis. On the multivariate logistic regression analysis, there were no independent variables associated with thyroid malignancy, including the elasticity score and strain ratio (all P > .05). Elastographic analysis using the elasticity score and strain ratio has limited ability to characterize the benignity or malignancy of thyroid nodules with an intermediate suspicion of malignancy based on the 2015 ATA guidelines. © 2017 by the American Institute of Ultrasound in Medicine.

  12. Clinical and molecular profile of newborns with confirmed or suspicious congenital adrenal hyperplasia detected after a public screening program implementation.

    Science.gov (United States)

    Kopacek, Cristiane; Prado, Mayara J; da Silva, Claudia M D; de Castro, Simone M; Beltrão, Luciana A; Vargas, Paula R; Grandi, Tarciana; Rossetti, Maria L R; Spritzer, Poli Mara

    2018-04-30

    To describe the results obtained in a neonatal screening program after its implementation and to assess the clinical and molecular profiles of confirmed and suspicious congenital adrenal hyperplasia cases. A cross-sectional study was conducted. Newborns with suspected disease due to high 17-hydroxyprogesterone levels and adjusted for birth weight were selected. Classical congenital adrenal hyperplasia (salt-wasting and simple virilizing forms) was diagnosed by an increase in 17-hydroxyprogesterone levels as confirmed in the retest, clinical evaluation, and genotype determined by SNaPshot and multiplex ligation-dependent probe amplification. After 24 months, 15 classic congenital adrenal hyperplasia cases were diagnosed in a total of 217,965 newborns, with an estimated incidence of 1:14,531. From 132 patients, seven non-classical and 14 heterozygous patients were screened for CYP21A2 mutations, and 96 patients presented false positives with wild type CYP21A2. On retest, increased 17-hydroxyprogesterone levels were found in classical congenital adrenal hyperplasia patients and showed significant correlation with genotype-related classical genital adrenal hyperplasia. The most frequent mutations were IVS2-13A/C>G followed by gene deletion or rearrangement events in the classical form. In non-classical and heterozygous diseases, p.Val282Leu was the most common mutation. The results underscore the effectiveness of congenital adrenal hyperplasia neonatal screening in the public health system and indicate that the adopted strategy was appropriate. The second sample collection along with genotyping of suspected cases helped to properly diagnose both severe and milder cases and delineate them from false positive patients. Copyright © 2018. Published by Elsevier Editora Ltda.

  13. The Usefulness of the Transabdominal Ultrasonography as a Screening Examination in the Evaluation of the Patient with Suspicious Gastric Disease

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Cheol; Shin, Hyeong Cheol; Kim, Hyung Hwan; Park, Seong Jin; Nam, Deok Ho; Bae, Won Kyung; Kim, Il Young; Jeong, Du Shin; Chung, Il Kwun [Soonchunhyang University, Cheonan Hospital, Cheonan (Korea, Republic of)

    2005-03-15

    To evaluate the usefulness of transabdominal ultrasonography as a screening examination in patients with suspicious gastric disease. We selected 141 patients with epigastric pain and who were found to have antral gastric wall thickening of more than 5 mm in transabdominal ultrasonography, and who underwent gastroscopy immediately following the ultrasonography examination, because we suspected that these patients had gastric disease. We measured the full thickness of the five layers of the gastric wall and evaluated the preservation of this five layered structure. We respectively compared the gastric wall thickness and the preservation of gastric layers in 26 normal, 91 gastritis, 12 gastric ulcer, and 12 gastric cancer patients, who were classified based on the gastroscopy results. The mean thicknesses of the gastric wall in the normal, gastritis, gastric ulcer and gastric cancer patients were 5.13{+-}0.14 mm, 6.71{+-}1.33 mm, 8.08{+-}2.80 mm, and 12.45{+-}3.70 mm, respectively. The gastric walls in the gastritis, gastric ulcer and gastric cancer patients were significantly thicker than that in the normal patients (p < 0.01). The gastric wall in the gastric cancer patients was significantly thicker than those in the gastritis and gastric ulcer patients (p < 0.01). However, the difference in the gastric wall thickness between the gastritis and gastric ulcer patients was not statistically significant (p > 0.01). Except for two patients with gastritis and three patients with gastric ulcer, the stratification of the gastric wall was preserved in all of the normal, gastritis and gastric ulcer patients, whereas it was disrupted in all of the patients with gastric cancer. Transabdominal ultrasonography in the fasting state may be a helpful and convenient modality, which can serve as a screening examination in the evaluation of gastric disease. Therefore, careful attention and effort are needed to evaluate the gastric wall during transabdominal ultrasonography

  14. Suspicious breast calcifications undergoing stereotactic biopsy in women ages 70 and over: Breast cancer incidence by BI-RADS descriptors.

    Science.gov (United States)

    Grimm, Lars J; Johnson, David Y; Johnson, Karen S; Baker, Jay A; Soo, Mary Scott; Hwang, E Shelley; Ghate, Sujata V

    2017-06-01

    To determine the malignancy rate overall and for specific BI-RADS descriptors in women ≥70 years who undergo stereotactic biopsy for calcifications. We retrospectively reviewed 14,577 consecutive mammogram reports in 6839 women ≥70 years to collect 231 stereotactic biopsies of calcifications in 215 women. Cases with missing images or histopathology and calcifications associated with masses, distortion, or asymmetries were excluded. Three breast radiologists determined BI-RADS descriptors by majority. Histology, hormone receptor status, and lymph node status were correlated with BI-RADS descriptors. There were 131 (57 %) benign, 22 (10 %) atypia/lobular carcinomas in situ, 55 (24 %) ductal carcinomas in situ (DCIS), and 23 (10 %) invasive diagnoses. Twenty-seven (51 %) DCIS cases were high-grade. Five (22 %) invasive cases were high-grade, two (9 %) were triple-negative, and three (12 %) were node-positive. Malignancy was found in 49 % (50/103) of fine pleomorphic, 50 % (14/28) of fine linear, 25 % (10/40) of amorphous, 20 % (3/15) of round, 3 % (1/36) of coarse heterogeneous, and 0 % (0/9) of dystrophic calcifications. Among women ≥70 years that underwent stereotactic biopsy for calcifications only, we observed a high rate of malignancy. Additionally, coarse heterogeneous calcifications may warrant a probable benign designation. • Cancer rates of biopsied calcifications in women ≥70 years are high • Radiologists should not dismiss suspicious calcifications in older women • Coarse heterogeneous calcifications may warrant a probable benign designation.

  15. Retrospective analysis of suspicious pelvic masses using the Pelvic Mass Index (PMI) scoring system from 2007 to 2014.

    Science.gov (United States)

    Sinha, Anju; Drews, Florian; Lim, Kenneth; Pugh, Neil D

    2016-06-01

    This study aims to validate the accuracy of the Pelvic Mass Index (PMI) by comparing it with Risk of Malignancy Index (RMI) in a large patient cohort. This retrospective study used data of women with ovarian masses collected from 2007 to 2014, referred to the Pelvic Mass Clinic (PMC) at University Hospital of Wales in Cardiff. The locally developed PMI was used to triage patients for surgery, surveillance or discharge. Performance measures for PMI, RMI and CA125 are reported as sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), receiver operating characteristic (ROC) curves and area under the curve (AUC) for premenopausal and postmenopausal women alike. PMI was calculated on 1468 patients of whom 497 underwent surgery, 176 (71.0%) were in the high risk group, 63 (68.0%) intermediate and 258 (23%) amongst low risk women. Compared to RMI, PMI had a higher sensitivity (90.4%) and NPV (96.9%) for the entire cohort, as well as in the premenopausal (88.9%; 97.6%) and postmenopausal (91.5%; 95.6%) subcategories. ROC curves indicated better performance in the total group (AUC 0.823 vs. 0.770) and the premenopausal group (AUC 0.847 vs. 0.728), though AUC in the postmenopausal group was similar (0.779 vs. 0.791) - likely due to increased specificity of CA125 after menopause. Histology revealed PMI significantly outperforms RMI in diagnosing malignancy, missing only 1 compared to 20 cancers. The high sensitivity and NPV of PMI makes it a useful tool in triaging patients with suspicious ovarian masses. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. The Usefulness of the Transabdominal Ultrasonography as a Screening Examination in the Evaluation of the Patient with Suspicious Gastric Disease

    International Nuclear Information System (INIS)

    Kim, Hyun Cheol; Shin, Hyeong Cheol; Kim, Hyung Hwan; Park, Seong Jin; Nam, Deok Ho; Bae, Won Kyung; Kim, Il Young; Jeong, Du Shin; Chung, Il Kwun

    2005-01-01

    To evaluate the usefulness of transabdominal ultrasonography as a screening examination in patients with suspicious gastric disease. We selected 141 patients with epigastric pain and who were found to have antral gastric wall thickening of more than 5 mm in transabdominal ultrasonography, and who underwent gastroscopy immediately following the ultrasonography examination, because we suspected that these patients had gastric disease. We measured the full thickness of the five layers of the gastric wall and evaluated the preservation of this five layered structure. We respectively compared the gastric wall thickness and the preservation of gastric layers in 26 normal, 91 gastritis, 12 gastric ulcer, and 12 gastric cancer patients, who were classified based on the gastroscopy results. The mean thicknesses of the gastric wall in the normal, gastritis, gastric ulcer and gastric cancer patients were 5.13±0.14 mm, 6.71±1.33 mm, 8.08±2.80 mm, and 12.45±3.70 mm, respectively. The gastric walls in the gastritis, gastric ulcer and gastric cancer patients were significantly thicker than that in the normal patients (p 0.01). Except for two patients with gastritis and three patients with gastric ulcer, the stratification of the gastric wall was preserved in all of the normal, gastritis and gastric ulcer patients, whereas it was disrupted in all of the patients with gastric cancer. Transabdominal ultrasonography in the fasting state may be a helpful and convenient modality, which can serve as a screening examination in the evaluation of gastric disease. Therefore, careful attention and effort are needed to evaluate the gastric wall during transabdominal ultrasonography

  17. Code of practice for the design of laboratories using radioactive substances for medical purposes

    International Nuclear Information System (INIS)

    1981-01-01

    This Code has been prepared to supplement the radioactive substances acts and regulations implemented in Australia. It is intended as a guide to safe practices but is not legislation. Areas covered include siting, layout, surface finishes, laboratory furniture and fittings, ventilation, containment and release of airborne effluent and storage of radioactive substances

  18. Prospects for inherently safe reactors

    International Nuclear Information System (INIS)

    Barkenbus, J.N.

    1988-01-01

    Public fears over nuclear safety have led some within the nuclear community to investigate the possibility of producing inherently safe nuclear reactors; that is, reactors that are transparently incapable of producing a core melt. While several promising designs of such reactors have been produced, support for large-scale research and development efforts has not been forthcoming. The prospects for commercialization of inherently safe reactors, therefore, are problematic; possible events such as further nuclear reactor accidents and superpower summits, could alter the present situation significantly. (author)

  19. Is nuclear power safe enough

    Energy Technology Data Exchange (ETDEWEB)

    Andresen, A F [Institutt for Atomenergi, Kjeller (Norway)

    1979-01-01

    The lecture formed a commentary on the report of the Norwegian Government's Commission on Nuclear power Safety which was published in October 1978. It was introductorily pointed out that 'safe' and 'safety' are not in themselves meaningful terms and that the probability of an occurrence is the real measure. The main items in the Commission's report have been core meltdown, releases during reprocessing, waste disposal, plutonium diversion and environmental impacts. The 21 members of the Commission were unanimous in 7 of the 8 chapters. In chapter 2, 'Summary and Conclusions', 3 members dissented from the majority opinion, that, subject to certain conditions, nuclear power was a safe and acceptable source of energy.

  20. Safe and Liquid Mortgage Bonds

    DEFF Research Database (Denmark)

    Dick-Nielsen, Jens; Gyntelberg, Jacob; Lund, Jesper

    This paper shows that strict match pass-through funding of covered bonds provides safe and liquid mortgage bonds. Despite a 30% drop in house prices during the 2008 global crisis Danish mortgage bonds remained as liquid as most European government bonds. The Danish pass-through system effectively...... eliminates credit risk from the investor's perspective. Similar to other safe bonds, funding liquidity becomes the main driver of mortgage bond liquidity and this creates commonality in liquidity across markets and countries. These findings have implications for how to design a robust mortgage bond system...

  1. Safe-haven CDS Premia

    DEFF Research Database (Denmark)

    Klingler, Sven; Lando, David

    We argue that Credit Default Swap (CDS) premia for safe-haven sovereigns, like Germany and the United States, are driven to a large extent by regulatory requirements under which derivatives dealing banks have an incentive to buy CDS to hedge counterparty credit risk of their counterparties. We...

  2. Thermodynamics of asymptotically safe theories

    DEFF Research Database (Denmark)

    Rischke, Dirk H.; Sannino, Francesco

    2015-01-01

    We investigate the thermodynamic properties of a novel class of gauge-Yukawa theories that have recently been shown to be completely asymptotically safe, because their short-distance behaviour is determined by the presence of an interacting fixed point. Not only do all the coupling constants freeze...

  3. How Safe Are Our Libraries?

    Science.gov (United States)

    St. Lifer, Evan

    1994-01-01

    Addresses issues of safety and security in libraries. Topics discussed include keeping library collections safe; patron behavioral problems; factoring loss into the budget; staff theft; access versus security; apathy regarding library crime; a need for a unified security apparatus; preventive measures; staff and patron safety; and a…

  4. Safe disposal of radioactive wastes

    International Nuclear Information System (INIS)

    Hooker, P.; Metcalfe, R.; Milodowski, T.; Holliday, D.

    1997-01-01

    A high degree of international cooperation has characterized the two studies reported here which aim to address whether radioactive waste can be disposed of safely. Using hydrogeochemical and mineralogical surveying techniques earth scientists from the British Geological Survey have sought to identify and characterise suitable disposal sites. Aspects of the studies are explored emphasising their cooperative nature. (UK)

  5. Staying Safe on the Water

    Centers for Disease Control (CDC) Podcasts

    2008-06-05

    In this podcast for all audiences, Dr. Julie Gilchrist from CDC's Injury Center outlines tips for safe boating.  Created: 6/5/2008 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 6/8/2008.

  6. Safe transport of radioactive material

    International Nuclear Information System (INIS)

    1994-01-01

    Delivering radioactive material to where it is needed is a vital service to industry and medicine. Millions of packages are shipped all over the world by all modes of transport. The shipments pass through public places and must meet stringent safety requirements. This video explains how radioactive material is safely transported and describes the rules that carriers and handlers must follow

  7. Working safely with ionising radiation

    International Nuclear Information System (INIS)

    McDowell, D.J.

    1990-01-01

    A small leaflet provides information on working safely with ionizing radiation. Topics covered include the types of radiation, radiological units, external radiation, contamination and internal radiation, methods of protection form radiation, radiation monitors, protective clothing for contamination, personal dosemeters, radiation dose limits for classified workers and finally the Ionising Radiations Regulations 1985. (UK)

  8. Safe handling of radioactive isotopes. Handbook 42

    International Nuclear Information System (INIS)

    1949-09-01

    With the increasing use of radioactive isotopes by industry, the medical profession, and research laboratories, it is essential that certain minimal precautions be taken to protect the users and the public. The recommendations contained in this handbook represent what is believed to be the best available opinions on the subject as of this date. As our experience with radioisotopes broadens, we will undoubtedly be able to improve and strengthen the recommendations for their safe handling and utilization. Through the courtesy of the National Research Council about a year ago, several hundred draft copies of this report were circulated to all leading workers and authorities in the field for comment and criticism. The present handbook embodies all pertinent suggestions received from these people. Further comment will be welcomed by the committee. One of the greatest difficulties encountered in the preparation of this handbook lay in the uncertainty regarding permissible radiation exposure levels - particularly for ingested radioactive materials. The establishment of sound figures for such exposure still remains a problem of high priority for many conditions and radioactive substances. Such figures as are used in this report represent the best available information today. If, in the future, these can be improved upon, appropriate corrections will be issued. The subject will be under continuous study by the two subcommittees mentioned above. The present Handbook has been prepared by the Subcommittee on the Handling of Radioactive Isotopes and Fission Products

  9. Safe Handling of Radioisotopes. 1973 Edition

    International Nuclear Information System (INIS)

    1973-01-01

    Under its Statute the International Atomic Energy Agency is empowered to provide for the application of standards of safety for protection against radiation to its own operations and to operations making use of assistance provided by it or with which it is otherwise directly associated. To this end authorities receiving such assistance are required to observe relevant health and safety measures prescribed by the Agency. As a first step, it was considered an urgent task to provide users of radionuclides with a manual of practice for the safe handling of these substances. The first edition of such a manual was published in 1958 and represented the first of the ''Safety Series'', a series of manuals and codes on health and safety published by the Agency. It was prepared after careful consideration of existing national and international codes of radiation safety by a group of international experts and in consultation with other international bodies. This edition presents the second revision. In response to the suggestion made by some Member States, the term 'radioisotopes' has been changed to 'radionuclides' in the title and, as appropriate, in the text because the term 'radionuclides' includes the radioactive element itself as well as the isotopes. The series of manuals and codes published in the Safety Series and the Technical Reports Series give more complete advice to the user on specialized topics.

  10. Safe handling of radioactive isotopes. Handbook 42

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1949-09-15

    With the increasing use of radioactive isotopes by industry, the medical profession, and research laboratories, it is essential that certain minimal precautions be taken to protect the users and the public. The recommendations contained in this handbook represent what is believed to be the best available opinions on the subject as of this date. As our experience with radioisotopes broadens, we will undoubtedly be able to improve and strengthen the recommendations for their safe handling and utilization. Through the courtesy of the National Research Council about a year ago, several hundred draft copies of this report were circulated to all leading workers and authorities in the field for comment and criticism. The present handbook embodies all pertinent suggestions received from these people. Further comment will be welcomed by the committee. One of the greatest difficulties encountered in the preparation of this handbook lay in the uncertainty regarding permissible radiation exposure levels - particularly for ingested radioactive materials. The establishment of sound figures for such exposure still remains a problem of high priority for many conditions and radioactive substances. Such figures as are used in this report represent the best available information today. If, in the future, these can be improved upon, appropriate corrections will be issued. The subject will be under continuous study by the two subcommittees mentioned above. The present Handbook has been prepared by the Subcommittee on the Handling of Radioactive Isotopes and Fission Products.

  11. A safe radiation environment. Environmental Objective 13

    International Nuclear Information System (INIS)

    1999-01-01

    A safe radiation environment is one of the 15 environmental quality objectives that form the basis for developing a ecologically sustainable society within one generation. These objectives have been adopted by the Swedish parliament, and in the present report, the five different targets for reaching Objective 13 are defined. They are: (by year 2010) 1. The emissions of radioactive substances should be low enough to protect human beings, and the ecological diversity. 2. A generally accepted method for managing and disposing of spent nuclear fuels and radioactive waste should be available, that does not impose any risks for human beings and for the environment. 3. Hazards to the society, human beings or the environment from radiological accidents should be eradicated, or at least severely minimized. 4. Hazards from electromagnetic fields should be understood and, if necessary, actions planned for improving the e-m field environment. 5. The number of skin cancers in year 2020 from solar radiation should not exceed those in year 2000

  12. Substance abuse in anaesthetists.

    Science.gov (United States)

    Garcia-Guasch, Roser; Roigé, Jaume; Padrós, Jaume

    2012-04-01

    Anaesthesiologists have a significantly higher frequency of substance abuse by a factor of nearly 3 when compared with other physicians. This is still a current problem that must be reviewed. Many hypotheses have been formulated to explain why anaesthesiologists appear to be more susceptible to substance abuse than other medical professionals (genetic differences in sensitivity to opioids, stress, the association between chemical dependence and other psychopathology or the second-hand exposure hypothesis). Environmental exposure and sensitization may be an important risk factor in physician addiction. There is a long debate about returning to work for an anaesthetist who has been depending on opioid drugs, and recent debates are discussed. Institutional efforts have been made in many countries and physician health programmes have been developed. As drug abuse among anaesthesiologists has continued, new studies have been conducted to know the theories about susceptibility. Written substance abuse policies and controls must be taken in place and in all countries.

  13. Detection of diffusible substances

    Energy Technology Data Exchange (ETDEWEB)

    Warembourg, M [Lille-1 Univ., 59 - Villeneuve-d' Ascq (France)

    1976-12-01

    The different steps of a radioautographic technique for the detection of diffusible substances are described. Using this radioautographic method, the topographic distribution of estradiol-concentrating neurons was studied in the nervous system and pituitary of the ovariectomized mouse and guinea-pig. A relatively good morphological preservation of structures can be ascertained on sections from unfixed, unembedded tissues prepared at low temperatures and kept-under relatively low humidity. The translocation or extraction of diffusible substances is avoided by directly mounting of frozen sections on dried photographic emulsion. Since no solvent is used, this technique excludes the major sources of diffusion artifacts and permits to be in favourable conditions for the localization of diffusible substances.

  14. Substance abuse and cancer.

    Science.gov (United States)

    Moussas, G I; Papadopoulou, A G

    2017-01-01

    Substance abuse is a health problem with serious psychological and psychiatric dimensions and multiple social and economic consequences. Cancer is a disease that threatens not only life and physical integrity but mental health as well. Oncology patients suffer from mental disorders in high rates, especially from depression and anxiety. The role of substance abuse in the pathogenesis of cancer is studied systematically, since there are research data supporting the mutagenic effects of certain substances. It has been supported that a possible dysregulation of the immune system is linked to the oncogenic processes induced by substances of abuse. Specifically, opioids are the first addictive substances that have been identified as oncogenic factors. However, conflicting results have been offered by experimental animal studies, which showed that opioids, such as morphine, depending on the dosage administered, may not only enhance the process of tumor growth, but also inhibit it. Additionally, research data indicate that the use of cannabis may be associated with cancer, either as an independent factor or in relation to other mutagenics, although it is not yet clear to which extent these effects may be connected to the disease, especially once the consumption of tobacco and alcohol by these patients are taken into account. However, it has been argued that certain cannabinoids may have biological -anticancer- activities which could be used therapeutically without being accompanied by the corresponding 9-tetrahydrocannabinol psychoactive effects. It is well known that alcohol is a risk factor for developing head and neck cancer, and epidemiological studies indicate that the higher the consumption of alcohol, the more mortality due to cancer increases. In addition, it is suggested that there is no safety level for alcohol consumption regarding the risk of developing cancer; that is even a minimum daily consumption is associated with the occurrence of certain types of cancer

  15. Egyptian Environmental Activities and Regulations for Management of Hazardous Substances and Hazardous Wastes

    International Nuclear Information System (INIS)

    El Zarka, M.

    1999-01-01

    A substantial use of hazardous substances is essential to meet the social and economic goals of the community in Egypt. Agrochemicals are being used extensively to increase crop yield. The outdated agrochemicals and their empty containers represent a serious environmental problem. Industrial development in different sectors in Egypt obligates handling of huge amounts of hazardous substances and hazardous wastes. The inappropriate handling of such hazardous substances creates several health and environmental problems. Egypt faces many challenges to control safe handling of such substances and wastes. Several regulations are governing handling of hazardous substances in Egypt. The unified Environmental Law 4 for the year 1994 includes a full chapter on the Management of Hazardous Substances and Hazardous Wastes. National and international activities have been taken to manage hazardous substances and hazardous wastes in an environmental sound manner

  16. Ensuring a Safe Technological Revolution

    Science.gov (United States)

    2016-12-01

    much lower, and the performance gained can dramatically reduce life -cycle costs. Validated cost data are scarce, and accurate AM cost models need to be...reduce costs, minimize obsolescence issues and improve both capability and readi- ness across the entire life cycle of naval systems—including both the...of naval weapon systems. The Navy is actively engaging its various communi- ties to align needs and ensure that AM can be safely acceler- ated and

  17. A National Evaluation of Safe Schools/Healthy Students: Outcomes and Influences

    Science.gov (United States)

    Derzon, James H.; Yu, Ping; Ellis, Bruce; Xiong, Sharon; Arroyo, Carmen; Mannix, Danyelle; Wells, Michael E.; Hill, Gary; Rollison, Julia

    2012-01-01

    The Safe Schools/Healthy Students (SS/HS) Initiative has awarded over $2 billion in grants to more than 350 school districts in partnership with local mental health, law enforcement, and juvenile justice agencies. To estimate the impact of grantee characteristics, grant operations, and near-term outcomes in reducing violence and substance use,…

  18. Symposium--The Safe Schools Healthy Students Initiative: The Evaluation Context in District Wide Initiatives.

    Science.gov (United States)

    Massey, Oliver T.; Armstrong, Kathleen; Lattimore, Pamela; Boroughs, Michael; Tucker, Joan; Santoro, Gina

    This report discusses the outcomes of two studies that investigated the effectiveness of the Safe Schools Healthy Students Initiative (SS/HSI), a federal grant program designed to promote healthy childhood development and prevent violence and substance abuse. The first study, titled "Results of a Longitudinal Study of Disciplinary Referrals…

  19. Transfer pricing and safe harbours

    Directory of Open Access Journals (Sweden)

    Veronika Solilová

    2013-01-01

    Full Text Available Transfer prices are significant for both taxpayers and tax administrations because they determine in large part taxable profits of associated enterprises in different tax jurisdictions. Moreover, in the context of taxation, transfer prices must be complied with the arm’s length principle. However, Multinational Enterprises have been faced daily by conflicting rules and approaches to applying the arm’s length principle, burdensome documentation requirements, inconsistent audit standards and unpredictable competent authority outcomes. Therefore, the Committee on Fiscal Affairs launched another project on the administrative aspects of transfer pricing in 2010. On 16 May 2013 as a partial solution of this project was approved by the OECD Council the Revised Section E on Safe Harbours in Chapter IV of the Transfer Pricing Guidelines for Multinational Enterprises and Tax Authorities. The paper is focused on significant changes of newly approved chapter IV of the Transfer Pricing Guidelines for Multinational Enterprises and Tax Authorities, further on analysis of practice in this area, on advantages and disadvantages of safe harbours for taxpayers and competent authorities with aim to suggest recommendations on use of safe harbours in the Czech Republic.

  20. Yellow substance (gelbstoff)

    International Nuclear Information System (INIS)

    Medina, A.

    1988-04-01

    The different values of the mean slope (S) of the absorption coefficient a(λ) of gelbstoff (yellow substance) for each region under the same hydrological conditions and the correlation between the quantity of absorption (CA) of gelbstoff and sea water parameter is discussed. 12 refs, 6 figs, 3 tabs

  1. Adolescent Substance Abuse.

    Science.gov (United States)

    Thorne, Craig R.; DeBlassie, Richard R.

    1985-01-01

    Cummings (1979), citing evidence from the National Institute of Drug Abuse, reports that one of every eleven adult Americans suffers from a severe addictive problem. Drug addiction is epidemic among teenagers; one of every six teenagers suffers from a severe addictive problem. This paper focuses on adolescent drug/substance abuse. (Author)

  2. Eyes with Suspicious Appearance of the Optic Disc and Normal Intraocular Pressure: Using Clinical and Epidemiological Characteristics to Differentiate Those with and without Glaucoma.

    Directory of Open Access Journals (Sweden)

    Diego T Dias

    Full Text Available Among all glaucoma suspects, eyes with optic nerve head features suspicious or suggestive of early glaucoma are probably those that offer the greatest challenge for clinicians. In contrast with the robust longitudinal data published on ocular hypertension, there is no specific management guideline for these patients. Therefore, evaluating eyes with suspicious optic disc appearance and normal intraocular pressure (IOP, we sought to investigate potential differences in clinical and epidemiological characteristics to differentiate those with normal-tension glaucoma (NTG from those with presumed large physiological optic disc cups (pLPC. In this observational case-control study, we consecutively enrolled individuals with pLPC and NTG. All eyes had vertical cup-to-disc ratio (VCDR≥0.6 and untreated IOP<21 mmHg. Glaucomatous eyes had reproducible visual field defects. Eyes with pLPC required normal visual fields and ≥30 months of follow-up with no evidence of glaucomatous neuropathy. Clinical and epidemiological parameters were compared between groups. Eighty-four individuals with pLPC and 40 NTG patients were included. Regarding our main results, NTG patients were significantly older and with a higher prevalence of Japanese descendants (p<0.01. Not only did pLPC eyes have smaller mean VCDR, but also larger optic discs (p≤0.04. There were no significant differences for gender, central corneal thickness, and spherical equivalent (p≥0.38. Significant odds ratios (OR were found for race (OR = 2.42; for Japanese ancestry, age (OR = 1.05, VCDR (OR = 5.03, and disc size (OR = 0.04; p≤0.04. In conclusion, in patients with suspicious optic disc and normal IOP, those with older age, Japanese ancestry, smaller optic discs, and larger VCDR are more likely to have NTG, and therefore, deserve deeper investigation and closer monitoring.

  3. Fast and Noninvasive Characterization of Suspicious Lesions Detected at Breast Cancer X-Ray Screening: Capability of Diffusion-weighted MR Imaging with MIPs.

    Science.gov (United States)

    Bickelhaupt, Sebastian; Laun, Frederik B; Tesdorff, Jana; Lederer, Wolfgang; Daniel, Heidi; Stieber, Anne; Delorme, Stefan; Schlemmer, Heinz-Peter

    2016-03-01

    To evaluate the ability of a diagnostic abbreviated magnetic resonance (MR) imaging protocol consisting of maximum intensity projections (MIPs) from diffusion-weighted imaging with background suppression (DWIBS) and unenhanced morphologic sequences to help predict the likelihood of malignancy on suspicious screening x-ray mammograms, as compared with an abbreviated contrast material-enhanced MR imaging protocol and a full diagnostic breast MR imaging protocol. This prospective institutional review board-approved study included 50 women (mean age, 57.1 years; range, 50-69 years), who gave informed consent and who had suspicious screening mammograms and an indication for biopsy, from September 2014 to January 2015. Before biopsy, full diagnostic contrast-enhanced MR imaging was performed that included DWIBS (b = 1500 sec/mm(2)). Two abbreviated protocols (APs) based on MIPs were evaluated regarding the potential to exclude malignancy: DWIBS (AP1) and subtraction images from the first postcontrast and the unenhanced series (AP2). Diagnostic indexes of both methods were examined by using the McNemar test and were compared with those of the full diagnostic protocol and histopathologic findings. Twenty-four of 50 participants had a breast carcinoma. With AP1 (DWIBS), the sensitivity was 0.92 (95% confidence interval [CI]: 0.73, 0.98), the specificity was 0.94 (95% CI: 0.77, 0.99), the negative predictive value (NPV) was 0.92 (95% CI: 0.75, 0.99), and the positive predictive value (PPV) was 0.93 (95% CI: 0.75, 0.99). The mean reading time was 29.7 seconds (range, 4.9-110.0 seconds) and was less than 3 seconds (range, 1.2-7.6 seconds) in the absence of suspicious findings on the DWIBS MIPs. With the AP2 protocol, the sensitivity was 0.85 (95% CI: 0.78, 0.95), the specificity was 0.90 (95% CI: 0.72, 0.97), the NPV was 0.87 (95% CI: 0.69, 0.95), the PPV was 0.89 (95% CI: 0.69, 0.97), and the mean reading time was 29.6 seconds (range, 6.0-100.0 seconds). Unenhanced diagnostic

  4. Early experience with multiparametric magnetic resonance imaging-targeted biopsies under visual transrectal ultrasound guidance in patients suspicious for prostate cancer undergoing repeated biopsy

    DEFF Research Database (Denmark)

    Boesen, Lars; Noergaard, Nis; Chabanova, Elizaveta

    2015-01-01

    OBJECTIVES: The purpose of this study was to investigate the detection rate of prostate cancer (PCa) by multiparametric magnetic resonance imaging-targeted biopsies (mp-MRI-bx) in patients with prior negative transrectal ultrasound biopsy (TRUS-bx) sessions without previous experience of this......-RADS) and Likert classification. All underwent repeated TRUS-bx (10 cores) and mp-MRI-bx under visual TRUS guidance of any mp-MRI-suspicious lesion not targeted by systematic TRUS-bx. RESULTS: PCa was found in 39 out of 83 patients (47%) and mp-MRI identified at least one lesion with some degree of suspicion...

  5. Account Deletion Prediction on RuNet: A Case Study of Suspicious Twitter Accounts Active During the Russian-Ukrainian Crisis

    Energy Technology Data Exchange (ETDEWEB)

    Volkova, Svitlana; Bell, Eric B.

    2016-06-17

    Social networks are dynamically changing over time e.g., some accounts are being created and some are being deleted or become private. This ephemerality at both an account level and content level results from a combination of privacy concerns, spam, and deceptive behaviors. In this study we analyze a large dataset of 180,340 accounts active during the Russian-Ukrainian crisis to discover a series of predictive features for the removal or shutdown of a suspicious account. We find that unlike previously reported profile and net- work features, lexical features form the basis for highly accurate prediction of the deletion of an account.

  6. How safe are nuclear plants? How safe should they be?

    International Nuclear Information System (INIS)

    Kouts, H.

    1988-01-01

    It has become customary to think about safety of nuclear plants in terms of risk as defined by the WASH-1400 study that some of the implications for the non-specialist escape our attention. Yet it is known that a rational program to understand safety, to identify unsafe events, and to use this kind of information or analysis to improve safety, requires us to use the methods of quantitative risk assessment. How this process can be made more understandable to a broader group of nontechnical people and how can a wider acceptance of the results of the process be developed have been questions under study and are addressed in this report. These are questions that have been struggled with for some time in the world of nuclear plant safety. The Nuclear Regulatory Commission examined them for several years as it moved toward developing a position on safety goals for nuclear plants, a requirement that had been assigned it by Congress. Opinion was sought from a broad spectrum of individuals, within the field of nuclear power and outside it, on the topic that was popularly called, ''How safe is safe enough?'' Views were solicited on the answer to the question and also on the way the answer should be framed when it was adopted. This report discusses the public policy and its implementation

  7. Aversion substance(s) of the rat coagulating glands

    Science.gov (United States)

    Gawienowski, Anthony M.; Berry, Iver J.; Kennelly, James J.

    1982-01-01

    The aversive substance(s) present in adult male urine were not found in castrate rat urine. Removal of the coagulating glands also resulted in a loss of the aversion compounds. The aversion substances were restored to the urine after androgen treatment of the castrate rats.

  8. Psilocybin for treating substance use disorders?

    Science.gov (United States)

    de Veen, Bas T H; Schellekens, Arnt F A; Verheij, Michel M M; Homberg, Judith R

    2017-02-01

    Evidence based treatment for Substance use disorders (SUD) includes psychotherapy and pharmacotherapy. However, these are only partially effective. Hallucinogens, such as psilocybin, may represent potential new treatment options for SUD. This review provides a summary of (human) studies on the putative therapeutic effects of psilocybin, and discusses the receptor systems, brain regions and cognitive and emotional processes mediating psilocybin's effects. Psilocybin's chemical structure is similar to that of serotonin. Dysregulations in the serotonin system are associated with alterations in stress hormones, such as cortisol, and mood disorders. After psilocybin administration cortisol levels spike and activate the executive control network, with subsequent increased control over emotional processes, and relief of negative thinking and persistent negative emotions. Preliminary data of ongoing alcohol and smoking addiction studies in humans shows promising effects of psilocybin administration on substance use. Importantly, psilocybin has a low risk of toxicity and dependence and can be used safely under controlled clinical conditions. Areas covered: This paper is a narrative review based on the search terms: psilocybin, substance use disorder, addiction, depression, serotonin. Literature on potential efficacy and mechanisms of action of psilocybin in SUD is discussed. Expert commentary: Recent positive findings with psilocybin need confirmation in well-designed placebo controlled randomized trials employing a large sample size.

  9. Small intrinsically safe reactor implications

    International Nuclear Information System (INIS)

    Wakabayashi, Hiroaki

    1985-01-01

    Reviewing the history of nuclear power, it is found that peaceful uses of nuclear power are children of the war-like atom. Importance of special growth in a shielded environment is emphasized to exploit fully the advantages of nuclear power. Nuclear power reactors must be safe for their assimilation into society from the points of view of both technology and social psychology. ISR/ISER is identified as a missing link in the development of nuclear power reactors from this perspective and advocated for international development and utilization, being unleashed from the concerns of politicization, safety, and proliferation

  10. Mifrenz: Safe email for children

    Directory of Open Access Journals (Sweden)

    Tim Hunt

    Full Text Available Products currently available for monitoring children\\'s email usage are either considered to encourage dubious ethical behaviour or are time consuming for parents to administer. This paper describes the development of a new email client application for children called Mifrenz. This new application gives parents the ability to let their children safely use email, with the minimum of intervention. It was developed using mostly free software and also with the desire to provide real first hand programming examples to demonstrate to students.

  11. Type-safe pattern combinators

    DEFF Research Database (Denmark)

    Rhiger, Morten

    2009-01-01

    Macros still haven't made their way into typed higher-order programming languages such as Haskell and Standard ML. Therefore, to extend the expressiveness of Haskell or Standard ML, one must express new linguistic features in terms of functions that fit within the static type systems of these lan...... of these languages. This is particularly challenging when introducing features that span across multiple types and that bind variables. We address this challenge by developing, in a step by step manner, mechanisms for encoding patterns and pattern matching in Haskell in a type-safe way....

  12. Safe Detection System for Hydrogen Leaks

    Energy Technology Data Exchange (ETDEWEB)

    Lieberman, Robert A. [Intelligent Optical Systems, Inc., Torrance, CA (United States); Beshay, Manal [Intelligent Optical Systems, Inc., Torrance, CA (United States)

    2012-02-29

    Hydrogen is an "environmentally friendly" fuel for future transportation and other applications, since it produces only pure ("distilled") water when it is consumed. Thus, hydrogen-powered vehicles are beginning to proliferate, with the total number of such vehicles expected to rise to nearly 100,000 within the next few years. However, hydrogen is also an odorless, colorless, highly flammable gas. Because of this, there is an important need for hydrogen safety monitors that can warn of hazardous conditions in vehicles, storage facilities, and hydrogen production plants. To address this need, IOS has developed a unique intrinsically safe optical hydrogen sensing technology, and has embodied it in detector systems specifically developed for safety applications. The challenge of using light to detect a colorless substance was met by creating chemically-sensitized optical materials whose color changes in the presence of hydrogen. This reversible reaction provides a sensitive, reliable, way of detecting hydrogen and measuring its concentration using light from low-cost LEDs. Hydrogen sensors based on this material were developed in three completely different optical formats: point sensors ("optrodes"), integrated optic sensors ("optical chips"), and optical fibers ("distributed sensors") whose entire length responds to hydrogen. After comparing performance, cost, time-to-market, and relative market need for these sensor types, the project focused on designing a compact optrode-based single-point hydrogen safety monitor. The project ended with the fabrication of fifteen prototype units, and the selection of two specific markets: fuel cell enclosure monitoring, and refueling/storage safety. Final testing and development of control software for these markets await future support.

  13. Mammographic evaluation of suspicious malignant lesions based on ACR(American College of Radiology) breast imaging reporting and data system(BI-RADS)

    International Nuclear Information System (INIS)

    Lee, Jei Hee; Oh, Ki Keun; Chang, So Yong; Kim, Eun Kyung; Kim, Mi Hye

    1999-01-01

    The purpose of this study was to assess the mammographic features and pathologic outcome of category 4 lesions using the Breast Imaging Reporting and Data System(BI-RADS), and to evaluate the significance of final assessment categories. Using BI-RADS, the interpretations of 8,134 mammograms acquired between January 1997 and May 1998 were categorized. From among 161 lesions categorized as '4' ('suspicious abnormality') and pathologically confirmed by surgery or biopsy, we analysed 113, found in 66 patients. The pathologic outcome of these 113 lesions was as follows:infiltrating ductal carcinoma, 17.7%(20/113); DCIS(ductal carcinoma in sitv), 8.0%(9/113); ADH(atypical ductal hyperplasia), 5.3%(6/113); DEH(ductal epithelial hyperplasia), 1.8%(2/113); ductectasia, 0.9%(1/113), FCD(fibrocystic change), 27.4%(31/113); firoadenoma, 7.1%(8/113); stromal fibrosis, 9.7%(11/113); normal parenchyma, 7.1%(8/113); other pathology, 15.0%(17/113). The most frequent mammographic features of BI-RADS category 4 lesions were irregular mass shape(41.2%), spiculated mass margin(52.3%), amorphous calcification(47.3%) and clustered calcification distribution(37.1%). Because category 4 lesions account for about 25.7% of all breast malignancies, mammographic lesions in this category ('suspicious abnormality') should be considered for supplementary study and breast biopsy rather than short-term follow-up. Initial pathologic findings can thus be confirmed

  14. Application of classification trees for the qualitative differentiation of focal liver lesions suspicious for metastasis in gadolinium-EOB-DTPA-enhanced liver MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Schelhorn, J. [Sophien und Hufeland Klinikum, Weimar (Germany). Dept. of Radiology and Nuclear Medicine; Benndorf, M.; Dietzel, M.; Burmeister, H.P.; Kaiser, W.A.; Baltzer, P.A.T. [Jena Univ. (Germany). Inst. of Diagnostic and Interventional Radiology

    2012-09-15

    Purpose: To evaluate the diagnostic accuracy of qualitative descriptors alone and in combination for the classification of focal liver lesions (FLLs) suspicious for metastasis in gadolinium-EOB-DTPA-enhanced liver MR imaging. Materials and Methods: Consecutive patients with clinically suspected liver metastases were eligible for this retrospective investigation. 50 patients met the inclusion criteria. All underwent Gd-EOB-DTPA-enhanced liver MRI (T2w, chemical shift T1w, dynamic T1w). Primary liver malignancies or treated lesions were excluded. All investigations were read by two blinded observers (O1, O2). Both independently identified the presence of lesions and evaluated predefined qualitative lesion descriptors (signal intensities, enhancement pattern and morphology). A reference standard was determined under consideration of all clinical and follow-up information. Statistical analysis besides contingency tables (chi square, kappa statistics) included descriptor combinations using classification trees (CHAID methodology) as well as ROC analysis. Results: In 38 patients, 120 FLLs (52 benign, 68 malignant) were present. 115 (48 benign, 67 malignant) were identified by the observers. The enhancement pattern, relative SI upon T2w and late enhanced T1w images contributed significantly to the differentiation of FLLs. The overall classification accuracy was 91.3 % (O1) and 88.7 % (O2), kappa = 0.902. Conclusion: The combination of qualitative lesion descriptors proposed in this work revealed high diagnostic accuracy and interobserver agreement in the differentiation of focal liver lesions suspicious for metastases using Gd-EOB-DTPA-enhanced liver MRI. (orig.)

  15. A Fast-Track Referral System for Skin Lesions Suspicious of Melanoma: Population-Based Cross-Sectional Study from a Plastic Surgery Center

    Directory of Open Access Journals (Sweden)

    Reem Dina Jarjis

    2016-01-01

    Full Text Available Introduction. To minimize delay between presentation, diagnosis, and treatment of cutaneous melanoma (CM, a national fast-track referral system (FTRS was implemented in Denmark. The aim of this study was to analyze the referral patterns to our department of skin lesions suspicious of melanoma in the FTRS. Methods. Patients referred to the Department of Plastic Surgery and Breast Surgery in Zealand University Hospital were registered prospectively over a 1-year period in 2014. A cross-sectional study was performed analyzing referral patterns, including patient and tumor characteristics. Results. A total of 556 patients were registered as referred to the center in the FTRS for skin lesions suspicious of melanoma. Among these, a total of 312 patients (56.1% were diagnosed with CM. Additionally, 41 (7.4% of the referred patients were diagnosed with in situ melanoma. Conclusion. In total, 353 (63.5% patients had a malignant or premalignant melanocytic skin lesion. When only considering patients who where referred without a biopsy, the diagnostic accuracy for GPs and dermatologists was 29% and 45%, respectively. We suggest that efforts of adequate training for the referring physicians in diagnosing melanocytic skin lesions will increase diagnostic accuracy, leading to larger capacity in secondary care for the required treatment of malignant skin lesions.

  16. Post-clip placement MRI following second-look US-guided core biopsy for suspicious lesions identified on breast MRI

    International Nuclear Information System (INIS)

    Song, Sung Eun; Cho, Nariya; Han, Wonshik

    2017-01-01

    To evaluate whether the post-clip placement MRI following second-look ultrasound (US)-guided core biopsy is useful to confirm the adequate sampling of suspicious lesions identified on breast MRI. Between 2014 and 2016, 31 consecutive women with 34 suspicious lesions that had not been identified on previous mammography or US were detected using MRI. Among them, 26 women with 29 lesions (mean size 1.5 cm, range 0.5-5.8 cm) found by second-look US underwent US-guided biopsy, subsequent clip insertion and post-clip placement MRI. Five women with five lesions that were not found by second-look US underwent MRI-guided biopsy. The technical success rate and lesion characteristics were described. The technical success rate was 96.6% (28/29). One failure case was a benign, 1.1-cm non-mass enhancement. Of the 28 success cases, 23 (82.1%) were masses and 5 (17.9%) were non-mass enhancements; 17 (60.7%) were benign, 4 (14.3%) were high-risk and 7 (25.0%) were malignant lesions. The technical success rate was 100% (28/28) for masses and 83.3% (5/6) for non-mass enhancements. Post-clip placement MRI following US-guided biopsy is useful in confirming the adequate sampling of lesions identified on MRI. This method could be an alternative to MRI-guided biopsy for lesions visible on US. (orig.)

  17. Post-clip placement MRI following second-look US-guided core biopsy for suspicious lesions identified on breast MRI

    Energy Technology Data Exchange (ETDEWEB)

    Song, Sung Eun [Seoul National University Hospital, Department of Radiology, Seoul (Korea, Republic of); Korea University Anam Hospital, Korea University College of Medicine, Department of Radiology, Seoul (Korea, Republic of); Cho, Nariya [Seoul National University Hospital, Department of Radiology, Seoul (Korea, Republic of); Seoul National University College of Medicine, Department of Radiology, Seoul (Korea, Republic of); Seoul National University Medical Research Centre, Institute of Radiation Medicine, Seoul (Korea, Republic of); Han, Wonshik [Seoul National University Hospital, Department of Surgery, Seoul (Korea, Republic of)

    2017-12-15

    To evaluate whether the post-clip placement MRI following second-look ultrasound (US)-guided core biopsy is useful to confirm the adequate sampling of suspicious lesions identified on breast MRI. Between 2014 and 2016, 31 consecutive women with 34 suspicious lesions that had not been identified on previous mammography or US were detected using MRI. Among them, 26 women with 29 lesions (mean size 1.5 cm, range 0.5-5.8 cm) found by second-look US underwent US-guided biopsy, subsequent clip insertion and post-clip placement MRI. Five women with five lesions that were not found by second-look US underwent MRI-guided biopsy. The technical success rate and lesion characteristics were described. The technical success rate was 96.6% (28/29). One failure case was a benign, 1.1-cm non-mass enhancement. Of the 28 success cases, 23 (82.1%) were masses and 5 (17.9%) were non-mass enhancements; 17 (60.7%) were benign, 4 (14.3%) were high-risk and 7 (25.0%) were malignant lesions. The technical success rate was 100% (28/28) for masses and 83.3% (5/6) for non-mass enhancements. Post-clip placement MRI following US-guided biopsy is useful in confirming the adequate sampling of lesions identified on MRI. This method could be an alternative to MRI-guided biopsy for lesions visible on US. (orig.)

  18. Sonographically-guided vacuum-assisted biopsy with digital mammography-guided skin marking of suspicious breast microcalcifications: comparison of outcomes with stereotactic biopsy in Asian women.

    Science.gov (United States)

    Hahn, Soo Yeon; Shin, Jung Hee; Han, Boo-Kyung; Ko, Eun Young

    2011-02-01

    Management of suspicious microcalcifications in very thin breasts is problematic. To evaluate whether sonographically-guided vacuum-assisted biopsy (USVAB) with digital mammography-guided skin marking (DM) for the diagnosis of breast microcalcifications is comparable to stereotactic-guided vacuum-assisted biopsy (SVAB) in Asian women with thin breasts. Retrospective review was performed for 263 consecutive suspicious microcalcification lesions in 261 women who underwent USVAB with DM or SVAB using a prone table between January 2004 and December 2007. SVAB was performed for 190 lesions and USVAB for 73 lesions. Biopsy results were correlated with surgical pathology or followed up for at least 12 months. The diagnostic outcomes of SVAB and USVAB to diagnose microcalcifications were compared. Of 263 lesions, 104 (40%) underwent surgery and 159 (60%) were followed up. SVAB and USVAB groups showed similar final categories or the extent of microcalcifications. US visible lesions were 57 (78%) of 73 at USVAB and 14 (10%) of 140 at SVAB. Of 57 US visible lesions at USVAB, 29 (51%) were not found in initial US but were detectable with the help of DM. Specimen radiographs were negative in 2.1% of lesions at SVAB and in 4.1% at USVAB (p=0.4008). The under-estimation rate and false-negative rate were similar in SVAB and USVAB. US with DM facilitates US visibility of microcalcifications. USVAB with DM can produce acceptable biopsy results, as can SVAB, to diagnose breast microcalcifications in patients with thin breasts.

  19. Pathways to Preventing Substance Use Among Youth in Foster Care.

    Science.gov (United States)

    Kim, Hyoun K; Buchanan, Rohanna; Price, Joseph M

    2017-07-01

    Substance use problems are highly prevalent among youth in foster care. Such problems in adolescence have long-lasting implications for subsequent adjustment throughout adulthood and even across generations. Although several programs have demonstrated positive results in reducing substance use in at-risk youth, few studies have systemically examined how such programs work for foster youth and whether they are effective for both genders. This study examined the efficacy of KEEP SAFE, a family-based and skill-focused program designed to prevent substance use and other related health risking behaviors among youth in foster care. We hypothesized that improving the caregiver-youth relationship would lead to later reductions in youths' involvement with deviant peers, which subsequently would lead to less substance use, and that this mechanism would work comparably for both genders. A sample of 259 youth (154 girls, ages 11-17 years) in foster care and their caregivers participated in a randomized controlled trial and was followed for 18 months post-baseline. Results indicated that the intervention significantly reduced substance use in foster youth at 18 months post-baseline and that the intervention influenced substance use through two processes: youths' improved quality of relationships with caregivers at 6 months post-baseline and fewer associations with deviant peers at 12 months post-baseline. This suggests that these two processes may be fruitful immediate targets in substance use prevention programs for foster youth. We also found little gender differences in direct and mediating effects of the intervention, suggesting KEEP SAFE may be effective for both genders in foster care.

  20. Stroke And Substance Abuse

    OpenAIRE

    A Chitsaz

    2017-01-01

    Introduction: stroke in recreational substance users can be an indirect complication, like endocarditis and cardio embolism in parenteral drug users. With some drug like cocaine, stroke appear to be the result of a direct effect. In young subjects without other risk factors provide persuasive evidence for causality . OPIATES: Heroine is the most abused opiate drug, which is administered by injection, by snorting or by smoking. Stroke affects heroin users by diverse mechanisms,. Injec...

  1. Toxic Substances Control Act

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  2. Safe transport of radioactive material

    International Nuclear Information System (INIS)

    1990-01-01

    Recently the Agency redefined its policy for education and training in radiation safety. The emphasis is now on long-term strategic planning of general education and training programmes. In line with this general policy the Agency's Standing Advisory Group for the Safe Transport of Radioactive Material (SAGSTRAM) in its 7th meeting (April 1989) agreed that increased training activity should be deployed in the area of transport. SAGSTRAM specifically recommended the development of a standard training programme on this subject area, including audio-visual aids, in order to assist Member States in the implementation of the Agency's Regulations for the Safe Transport of Radioactive Material. This training programme should be substantiated by a biennial training course which is thought to be held either as an Interregional or a Regional Course depending on demand. This training manual, issued as a first publication in the Training Course Series, represents the basic text material for future training courses in transport safety. The topic areas covered by this training manual and most of the texts have been developed from the course material used for the 1987 Bristol Interregional Course on Transport Safety. The training manual is intended to give guidance to the lecturers of a course and will be provided to the participants for retention. Refs, figs and tabs

  3. Safe Driving After Propofol Sedation.

    Science.gov (United States)

    Summerlin-Grady, Lee; Austin, Paul N; Gabaldon, Dion A

    2017-10-01

    Propofol is a short-acting medication with fast cognitive and psychomotor recovery. However, patients are usually instructed not to drive a motor vehicle for 24 hours after receiving propofol. The purpose of this article was to review the evidence examining when it is safe to drive after receiving propofol for sedation for diagnostic and surgical procedures. This is a systematic review of the literature. A search of the literature was conducted using Google Scholar, PubMed, and the Cochrane Library for the time period 1990 to 2015. Two randomized controlled trials and two observational studies met the inclusion criteria. Using a simulator, investigators examined driving ability of subjects who received modest doses (about 100 mg) of propofol for endoscopic procedures and surveyed subjects who drove immediately after discharge. There were methodological concerns with the studies such as small sample sizes, modest doses of propofol, and three of the four studies were done in Japan by the same group of investigators limiting generalizability. This limited research suggests that it may be safe for patients to drive sooner than 24 hours after receiving propofol. However, large multicenter trials using heterogenous samples using a range of propofol doses are needed to support an evidence-based revision to the current discharge guidelines for patients receiving propofol. Copyright © 2016 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

  4. Keeping you safe by making machine tools safe

    CERN Multimedia

    2012-01-01

    CERN’s third safety objective for 2012 concerns the safety of equipment - and machine tools in particular.   There are three prerequisites for ensuring that a machine tool can be used safely: ·      the machine tool must comply with Directive 2009/104/EC, ·      the layout of the workshop must be compliant, and ·      everyone who uses the machine tool must be trained. Provided these conditions are met, the workshop head can grant authorisation to use the machine tool. To fulfil this objective, an inventory of the machine tools must be drawn up and the people responsible for them identified. The HSE Unit's Safety Inspection Service produces compliance reports for the machine tools. In order to meet the third objective set by the Director-General, the section has doubled its capacity to carry out inspections: ...

  5. Substance use in pregnancy.

    Science.gov (United States)

    Wong, Suzanne; Ordean, Alice; Kahan, Meldon

    2011-04-01

    To improve awareness and knowledge of problematic substance use in pregnancy and to provide evidence-based recommendations for the management of this challenging clinical issue for all health care providers. This guideline reviews the use of screening tools, general approach to care, and recommendations for clinical management of problematic substance use in pregnancy. Evidence-based recommendations for screening and management of problematic substance use during pregnancy and lactation. Medline, PubMed, CINAHL, and The Cochrane Library were searched for articles published from 1950 using the following key words: substance-related disorders, mass screening, pregnancy complications, pregnancy, prenatal care, cocaine, cannabis, methadone, opioid, tobacco, nicotine, solvents, hallucinogens, and amphetamines. Results were initially restricted to systematic reviews and randomized control trials/controlled clinical trials. A subsequent search for observational studies was also conducted because there are few RCTs in this field of study. Articles were restricted to human studies published in English. Additional articles were located by hand searching through article reference lists. Searches were updated on a regular basis and incorporated in the guideline up to December 2009. Grey (unpublished) literature was also identified through searching the websites of health technology assessment and health technology assessment-related agencies, clinical practice guideline collections, clinical trial registries, and national and international medical specialty societies. The quality of evidence was rated using the criteria described in the Report of the Canadian Task Force on the Preventive Health Care. Recommendations for practice were ranked according to the method described in that report (Table 1). This guideline is intended to increase the knowledge and comfort level of health care providers caring for pregnant women who have substance use disorders. Improved access to

  6. Dementia - keeping safe in the home

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000031.htm Dementia - keeping safe in the home To use the ... make sure the homes of people who have dementia are safe for them. Safety Tips for the ...

  7. Breastfeeding FAQs: Safely Storing Breast Milk

    Science.gov (United States)

    ... Search English Español Breastfeeding FAQs: Safely Storing Breast Milk KidsHealth / For Parents / Breastfeeding FAQs: Safely Storing Breast ... may have. How do I store my breast milk? You can freeze and/or refrigerate your pumped ( ...

  8. Self-medication hypothesis in substance-abusing psychotic patients: Can it help some subjects?

    Directory of Open Access Journals (Sweden)

    Susanta Kumar Padhy

    2016-01-01

    Full Text Available Background and Objectives: The evidence for gself.medication hypothesish (SMH in patients with dual diagnosis psychosis has been conflicting, though largely not supported, recently. But, still can SMH be a beneficial one in some patients with dual diagnosis remains a question. Methods: The study was conducted at Drug De.addiction and Treatment Centre, Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, a Tertiary Care Hospital in India. This cross.sectional comparative study had psychotic patients with substance use disorder as cases and those without substance use disorder as controls. Demographic details, clinical information, and Brief Psychiatric Rating Scale (BPRS scores were ascertained for cases and controls. Cases were additionally administered modified Stated Reasons Scale and modified Perceived Effects Scale. Results: Case and controls were comparable on demographic details and duration of psychotic illness, but cases had significantly lower scores on BPRS. The reasons reported for substance abuse in cases were more often nonhedonistic than hedonistic. Perceived effects of major substances of abuse (alcohol, cannabis, and opioids were different. Alcohol use was associated with perceived decrease in loneliness and cannabis was associated with perceived increase in suspiciousness and delusions. Considerable match was found between reasons for taking the substances and the effects perceived. Interpretation and Conclusions: Incorporating reasons for taking substance and their perceived effects in the treatment regimen would certainly help a subset of such difficult.to.treat patients. India being a low.resource country with a scarcity of experts and specialized dual diagnosis clinics, these findings may have an important implication in the clinical practice.

  9. 21 CFR 582.30 - Natural substances used in conjunction with spices and other natural seasonings and flavorings.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Natural substances used in conjunction with spices... with spices and other natural seasonings and flavorings. Natural substances used in conjunction with spices and other natural seasonings and flavorings that are generally recognized as safe for their...

  10. Working safely with electronics racks

    CERN Document Server

    Simon Baird, HSE Unit Head

    2016-01-01

    Think of CERN and you’ll probably think of particle accelerators and detectors. These are the tools of the trade in particle physics, but behind them are the racks of electronics that include power supplies, control systems and data acquisition networks.   Inside an electronics rack: danger could be lurking if the rack is not powered off. In routine operation, these are no more harmful than the home entertainment system in your living room. But unscrew the cover and it’s a different matter. Even after following appropriate training, and with formal authorisation from your group leader or equivalent to carry out electrical work or any work in the vicinity of electrical hazards, and even with extensive experience of carrying out such operations, it’s important to incorporate safe working practices into your routine. At CERN, before the racks of electronics reach their operational configurations for the accelerators and detectors, they play a vital role in test set-ups ...

  11. Workshop on Developing Safe Software

    International Nuclear Information System (INIS)

    Lawrence, J.D.

    1994-11-01

    The Workshop on Developing Safe Software was held July 22--23, 1992, at the Hotel del Coronado, San Diego, California. The purpose of the workshop was to have four world experts discuss among themselves software safety issues which are of interest to the US Nuclear Regulatory Commission. These issues concern the development of software systems for use in nuclear power plant protection systems. The workshop comprised four sessions. Wednesday morning, July 22, consisted of presentations from each of the four panel members. On Wednesday afternoon, the panel members went through a list of possible software development techniques and commented on them. The Thursday morning, July 23, session consisted of an extended discussion among the panel members and the observers from the NRC. A final session on Thursday afternoon consisted of a discussion among the NRC observers as to what was learned from the workshop

  12. Workshop on developing safe software

    International Nuclear Information System (INIS)

    Lawrence, J.D.

    1992-01-01

    The Workshop on Developing Safe Software was held July 22--23 at the Hotel del Coronado, San Diego, California. The purpose of the workshop was to have four world experts discuss among themselves software safety issues which are of interest to the U. S. Nuclear Regulatory Commission (NRC). These issues concern the development of software systems for use in nuclear power plant protection systems. The workshop comprised four sessions. Wednesday morning, July 22, consisted of presentations from each of the four panel members. On Wednesday afternoon, the panel members went through a list of possible software development techniques and commented on them. The Thursday morning, July 23, session consisted of an extended discussion among the panel members and the observers from the NRC. A final session on Thursday afternoon consisted of a discussion among the NRC observers as to what was teamed from the workshop

  13. The Difference Safe Spaces Make

    Directory of Open Access Journals (Sweden)

    Kendric Coleman

    2016-05-01

    Full Text Available In the last decade, lesbian, gay, bisexual, and transgender (LGBT students have become very visible at Historically Black Colleges and Universities (HBCUs, but this visibility is not reflected in some colleges’ student programs and activities. Only a few notable HBCUs, such as Howard University and Spelman College, have made a concerted effort. Acknowledging that the LGBT community is significant and exists, and fostering such support, comes up against a steep wall of religious tradition and doctrines, and conservative administrations. It is imperative that HBCUs address LGBT issues and create and support a safe space for students to articulate their identity. Meanwhile, many LGBT students on these campuses find voice and understanding in Black scholars and writers such as Audre Lorde’s Zami: A New Spelling of My Name and Charles Michael Smith’s Fighting Words: Personal Essays by Black Gay Men.

  14. Safe Distribution of Declarative Processes

    DEFF Research Database (Denmark)

    Hildebrandt, Thomas; Mukkamala, Raghava Rao; Slaats, Tijs

    2011-01-01

    of projections that covers a DCR Graph that the network of synchronously communicating DCR Graphs given by the projections is bisimilar to the original global process graph. We exemplify the distribution technique on a process identified in a case study of an cross-organizational case management system carried...... process model generalizing labelled prime event structures to a systems model able to finitely represent ω-regular languages. An operational semantics given as a transition semantics between markings of the graph allows DCR Graphs to be conveniently used as both specification and execution model....... The technique for distribution is based on a new general notion of projection of DCR Graphs relative to a subset of labels and events identifying the set of external events that must be communicated from the other processes in the network in order for the distribution to be safe.We prove that for any vector...

  15. Spark-safe power source

    Energy Technology Data Exchange (ETDEWEB)

    Mester, I M; Konushkin, N A; Nevozinskiy, A K; Rubinshteyn, B Sh; Serov, V I; Vasnev, M A

    1981-01-01

    A shortcoming of the known power sources is their low reliability. The purpose of the invention is to improve the reliability of the device. This is achieved because the spark-safe power source is equipped with a by-passing transistor and potentiometer, and also a generator of control interruptions in the circuit, an I-element, first separating transformer, control block, second separating transformer whose secondary winding has a relay winding whose contacts are connected to the load circuit are connected in series. The generator of control separations of the circuit is connected to the base of the by-passing transistor and to the power source outlet, the potentiometer is connected in series to the main thyristor. The middle point of the potentiometer is connected to the second inlet of the I-element.

  16. Safe injection procedures, injection practices, and needlestick ...

    African Journals Online (AJOL)

    Results: Safe injection procedures regarding final waste disposal were sufficiently adopted, while measures regarding disposable injection equipment, waste containers, hand hygiene, as well as injection practices were inadequately carried out. Lack of job aid posters that promote safe injection and safe disposal of ...

  17. Developing Safe Schools Partnerships with Law Enforcement

    Science.gov (United States)

    Rosiak, John

    2009-01-01

    Safe schools are the concern of communities throughout the world. If a school is safe, and if children feel safe, students "are better able to learn. But what are the steps to make" this happen? First, it is important to understand the problem: What are the threats to school safety? These include crime-related behaviors that find their way to…

  18. Safe Handover : Safe Patients - The Electronic Handover System.

    Science.gov (United States)

    Till, Alex; Sall, Hanish; Wilkinson, Jonathan

    2014-01-01

    Failure of effective handover is a major preventable cause of patient harm. We aimed to promote accurate recording of high-quality clinical information using an Electronic Handover System (EHS) that would contribute to a sustainable improvement in effective patient care and safety. Within our hospital the human factors associated with poor communication were compromising patient care and unnecessarily increasing the workload of staff due to the poor quality of handovers. Only half of handovers were understood by the doctors expected to complete them, and more than half of our medical staff felt it posed a risk to patient safety. We created a standardised proforma for handovers that contained specific sub-headings, re-classified patient risk assessments, and aided escalation of care by adding prompts for verbal handover. Sources of miscommunication were removed, accountability for handovers provided, and tasks were re-organised to reduce the workload of staff. Long-term, three-month data showed that each sub-heading achieved at least 80% compliance (an average improvement of approximately 40% for the overall quality of handovers). This translated into 91% of handovers being subjectively clear to junior doctors. 87% of medical staff felt we had reduced a risk to patient safety and 80% felt it increased continuity of care. Without guidance, doctors omit key information required for effective handover. All organisations should consider implementing an electronic handover system as a viable, sustainable and safe solution to handover of care that allows patient safety to remain at the heart of the NHS.

  19. Migrant workers’ occupation and healthcare-seeking preferences for TB-suspicious symptoms and other health problems: a survey among immigrant workers in Songkhla province, southern Thailand

    Directory of Open Access Journals (Sweden)

    Naing Tinzar

    2012-10-01

    Full Text Available Abstract Background Much of the unskilled and semi-skilled workforce in Thailand comprises migrant workers from neighbouring countries. While, in principle, healthcare facilities in the host country are open to those migrants registered with the Ministry of Labour, their actual healthcare-seeking preferences and practices, as well as those of unregistered migrants, are not well documented. This study aimed to describe the patterns of healthcare-seeking behaviours of immigrant workers in Thailand, emphasizing healthcare practices for TB-suspicious symptoms, and to identify the role of occupation and other factors influencing these behaviours. Methods A survey was conducted among 614 immigrant factory workers (FW, rubber tappers (RT and construction workers (CW, in which information was sought on socio-demography, history of illness and related healthcare-seeking behaviour. Mixed effects logistic regression modeling was employed in data analysis. Results Among all three occupations, self-medication was the most common way of dealing with illnesses, including the development of TB-suspicious symptoms, for which inappropriate drugs were used. Only for GI symptoms and obstetric problems did migrant workers commonly seek healthcare at modern healthcare facilities. For GI illness, FW preferred to attend the in-factory clinic and RT a private facility over government facilities owing to the quicker service and greater convenience. For RT, who were generally wealthier, the higher cost of private treatment was not a deterrent. CW preferentially chose a government healthcare facility for their GI problems. For obstetric problems, including delivery, government facilities were utilized by RT and CW, but most FW returned to their home country. After adjusting for confounding, having legal status in the country was associated with overall greater use of government facilities and being female and being married with use of both types of modern healthcare

  20. Safe Handover : Safe Patients – The Electronic Handover System

    Science.gov (United States)

    Till, Alex; Sall, Hanish; Wilkinson, Jonathan

    2014-01-01

    Failure of effective handover is a major preventable cause of patient harm. We aimed to promote accurate recording of high-quality clinical information using an Electronic Handover System (EHS) that would contribute to a sustainable improvement in effective patient care and safety. Within our hospital the human factors associated with poor communication were compromising patient care and unnecessarily increasing the workload of staff due to the poor quality of handovers. Only half of handovers were understood by the doctors expected to complete them, and more than half of our medical staff felt it posed a risk to patient safety. We created a standardised proforma for handovers that contained specific sub-headings, re-classified patient risk assessments, and aided escalation of care by adding prompts for verbal handover. Sources of miscommunication were removed, accountability for handovers provided, and tasks were re-organised to reduce the workload of staff. Long-term, three-month data showed that each sub-heading achieved at least 80% compliance (an average improvement of approximately 40% for the overall quality of handovers). This translated into 91% of handovers being subjectively clear to junior doctors. 87% of medical staff felt we had reduced a risk to patient safety and 80% felt it increased continuity of care. Without guidance, doctors omit key information required for effective handover. All organisations should consider implementing an electronic handover system as a viable, sustainable and safe solution to handover of care that allows patient safety to remain at the heart of the NHS. PMID:26734244

  1. Eye safe laser range finders

    International Nuclear Information System (INIS)

    Snir, M.; Margaliot, M.; Amitzi, A.

    2004-01-01

    During the 1970's, Ruby (Q switched) laser based range finders with a wavelength of 694nm were first used. These lasers operated in a pulse mode within the visible light range and produced a risk for the eye retina. The laser beam striking the macula could damage the eye and might cause blindness. Over the years, Nd:YAG (Q switched) lasers were developed (operating at 1064nm) for range finding and designation uses. The wavelength of these lasers, operating in the near Infra-Red range (invisible), is also focused tightly on the retina. The human eye does not respond to the invisible light so there is no natural protection (eye blink reflex) as in the visible light. The operation of these lasers worldwide, especially when the laser beam is exposed, causes occasional eye accidents. Another risk is stemming from the use of observation systems with a high optical gain, in the laser operation areas, which enlarge the range of risk quite significantly. Therefore, research and development efforts were invested in order to introduce eye safe lasers. One of the solutions for this problem is presented in following document

  2. Working safely with radioactive materials

    International Nuclear Information System (INIS)

    Davies, Wynne

    1993-01-01

    In common with exposure to many other laboratory chemicals, exposure to ionising radiations and to radioactive materials carries a small risk of causing harm. Because of this, there are legal limits to the amount of exposure to ionising radiations at work and special rules for working with radioactive materials. Although radiation protection is a complex subject it is possible to simplify to 10 basic things you should do -the Golden Rules. They are: 1) understand the nature of the hazard and get practical training; 2) plan ahead to minimise time spent handling radioactivity; 3) distance yourself appropriately from sources of radiation; 4) use appropriate shielding for the radiation; 5) contain radioactive materials in defined work areas; 6) wear appropriate protective clothing and dosimeters; 7) monitor the work area frequently for contamination control; 8) follow the local rules and safe ways of working; 9) minimise accumulation of waste and dispose of it by appropriate routes, and 10) after completion of work, monitor, wash, and monitor yourself again. These rules are expanded in this article. (author)

  3. Materials for passively safe reactors

    International Nuclear Information System (INIS)

    Simnad, T.

    1993-01-01

    Future nuclear power capacity will be based on reactor designs that include passive safety features if recent progress in advanced nuclear power developments is realized. There is a high potential for nuclear systems that are smaller and easier to operate than the current generation of reactors, especially when passive or intrinsic characteristics are applied to provide inherent stability of the chain reaction and to minimize the burden on equipment and operating personnel. Taylor, has listed the following common generic technical features as the most important goals for the principal reactor development systems: passive stability, simplification, ruggedness, case of operation, and modularity. Economic competitiveness also depends on standardization and assurance of licensing. The performance of passively safe reactors will be greatly influenced by the successful development of advanced fuels and materials that will provide lower fuel-cycle costs. A dozen new designs of advanced power reactors have been described recently, covering a wide spectrum of reactor types, including pressurized water reactors, boiling water reactors, heavy-water reactors, modular high-temperature gas-cooled reactors (MHTGRs), and fast breeder reactors. These new designs address the need for passive safety features as well as the requirement of economic competitiveness

  4. Safe and green nuclear power

    International Nuclear Information System (INIS)

    Kushwaha, H.S.

    2010-01-01

    Energy development plays an important role in the national economic growth. Presently the per capita consumption of energy in our country is about 750 kWh including captive power generation which is low in comparison to that in the developed countries like USA where it is about 12,000 kWh. As of now the total installed capacity of electricity generation is about 152,148 MW(e) which is drawn from Thermal (65%), Hydel (24%), Nuclear (3%) power plants and Renewables (8%). It is expected that by the end of year 2020, the required installed capacity would be more than 3,00,000 MW(e), if we assume per capita consumption of about 800-1000 kWh for Indian population of well over one billion. To meet the projected power requirement in India, suitable options need to be identified and explored for generation of electricity. For choosing better alternatives various factors such as availability of resources, potential to generate commercial power, economic viability, etc. need to be considered. Besides these factors, an important factor which must be taken into consideration is protection of environment around the operating power stations. This paper attempts to demonstrate that the nuclear power generation is an environmentally benign option for meeting the future requirement of electricity in India. It also discusses the need for creating the public awareness about the safe operations of the nuclear power plants and ionising radiation. (author)

  5. SAFE testing nuclear rockets economically

    International Nuclear Information System (INIS)

    Howe, Steven D.; Travis, Bryan; Zerkle, David K.

    2003-01-01

    Several studies over the past few decades have recognized the need for advanced propulsion to explore the solar system. As early as the 1960s, Werner Von Braun and others recognized the need for a nuclear rocket for sending humans to Mars. The great distances, the intense radiation levels, and the physiological response to zero-gravity all supported the concept of using a nuclear rocket to decrease mission time. These same needs have been recognized in later studies, especially in the Space Exploration Initiative in 1989. One of the key questions that has arisen in later studies, however, is the ability to test a nuclear rocket engine in the current societal environment. Unlike the Rover/NERVA programs in the 1960s, the rocket exhaust can no longer be vented to the open atmosphere. As a consequence, previous studies have examined the feasibility of building a large-scale version of the Nuclear Furnace Scrubber that was demonstrated in 1971. We have investigated an alternative that would deposit the rocket exhaust along with any entrained fission products directly into the ground. The Subsurface Active Filtering of Exhaust, or SAFE, concept would allow variable sized engines to be tested for long times at a modest expense. A system overview, results of preliminary calculations, and cost estimates of proof of concept demonstrations are presented. The results indicate that a nuclear rocket could be tested at the Nevada Test Site for under $20 M

  6. Substance abuse and child maltreatment.

    Science.gov (United States)

    Wells, Kathryn

    2009-04-01

    Pediatricians and other medical providers caring for children need to be aware of the dynamics in the significant relationship between substance abuse and child maltreatment. A caregiver's use and abuse of alcohol, marijuana, heroin, cocaine, methamphetamine, and other drugs place the child at risk in multiple ways. Members of the medical community need to understand these risks because the medical community plays a unique and important role in identifying and caring for these children. Substance abuse includes the abuse of legal drugs as well as the use of illegal drugs. The abuse of legal substances may be just as detrimental to parental functioning as abuse of illicit substances. Many substance abusers are also polysubstance users and the compounded effect of the abuse of multiple substances may be difficult to measure. Often other interrelated social features, such as untreated mental illness, trauma history, and domestic violence, affect these families.

  7. Hazardous substances shipping at inland water harbors

    International Nuclear Information System (INIS)

    Benkovic, Z.

    2009-01-01

    Safety measures and regulations system covering the aspects of fire protection, professional and ecological safety are aimed to create a safe working environment, by detection and remedy of conditions that are potentially hazardous for the well-being of the employees or are leading to certain undesired events. Such unwanted incidents may result in different consequences: operating person's injury, environment pollution or material damage. This study attempts to illustrate the organization of work during hazardous matter loading and unloading at inland water harbors, based on legal provisions and decrees involving safety precautions, and in order to achieve constant enhancement of operating procedure, decreasing thereby the number of work-related injuries and various accidental situations. Fundamental precondition required to prevent possible accidents and to optimize general safety policy is to recognize and control any danger or potential hazard, as well as to be familiar with the legal provisions covering the inland waterway transport of harmful substances.(author)

  8. Transport of nuclear substances in Canada

    Energy Technology Data Exchange (ETDEWEB)

    Faille, S. [Canadian Nuclear Safety Commission, Ottawa, ON (Canada)

    2015-07-01

    CNSC Regulates all Nuclear-related facilities and activities including Uranium mines and mill;, uranium fuel fabrication and processing; nuclear power plants; nuclear substance processing; industrial and medical applications; nuclear research and education; transport; export/import control; security and safeguards and waste management facilities. Our mandate is to protect the health, safety and security of Canadians and the environment, and implement Canada's International commitments on the peaceful use of nuclear energy and disseminate objective scientific, technical and regulatory information to the public. Based on the International Atomic Energy Agency (IAEA) Regulations for the Safe Transport of Radioactive Material, 1996 Edition, Revised and currently being revised to reflect the 2012 edition of the IAEA Regulations.

  9. Transport of nuclear substances in Canada

    International Nuclear Information System (INIS)

    Faille, S.

    2015-01-01

    CNSC Regulates all Nuclear-related facilities and activities including Uranium mines and mill;, uranium fuel fabrication and processing; nuclear power plants; nuclear substance processing; industrial and medical applications; nuclear research and education; transport; export/import control; security and safeguards and waste management facilities. Our mandate is to protect the health, safety and security of Canadians and the environment, and implement Canada's International commitments on the peaceful use of nuclear energy and disseminate objective scientific, technical and regulatory information to the public. Based on the International Atomic Energy Agency (IAEA) Regulations for the Safe Transport of Radioactive Material, 1996 Edition, Revised and currently being revised to reflect the 2012 edition of the IAEA Regulations.

  10. The SafeCOP ECSEL Project: Safe Cooperating Cyber-Physical Systems Using Wireless Communication

    DEFF Research Database (Denmark)

    Pop, Paul; Scholle, Detlef; Hansson, Hans

    2016-01-01

    This paper presents an overview of the ECSEL project entitled "Safe Cooperating Cyber-Physical Systems using Wireless Communication" (SafeCOP), which runs during the period 2016 -- 2019. SafeCOP targets safety-related Cooperating Cyber-Physical Systems (CO-CPS) characterised by use of wireless...... detection of abnormal behaviour, triggering if needed a safe degraded mode. SafeCOP will also develop methods and tools, which will be used to produce safety assurance evidence needed to certify cooperative functions. SafeCOP will extend current wireless technologies to ensure safe and secure cooperation...

  11. Post-clip placement MRI following second-look US-guided core biopsy for suspicious lesions identified on breast MRI.

    Science.gov (United States)

    Song, Sung Eun; Cho, Nariya; Han, Wonshik

    2017-12-01

    To evaluate whether the post-clip placement MRI following second-look ultrasound (US)-guided core biopsy is useful to confirm the adequate sampling of suspicious lesions identified on breast MRI. Between 2014 and 2016, 31 consecutive women with 34 suspicious lesions that had not been identified on previous mammography or US were detected using MRI. Among them, 26 women with 29 lesions (mean size 1.5 cm, range 0.5-5.8 cm) found by second-look US underwent US-guided biopsy, subsequent clip insertion and post-clip placement MRI. Five women with five lesions that were not found by second-look US underwent MRI-guided biopsy. The technical success rate and lesion characteristics were described. The technical success rate was 96.6% (28/29). One failure case was a benign, 1.1-cm non-mass enhancement. Of the 28 success cases, 23 (82.1%) were masses and 5 (17.9%) were non-mass enhancements; 17 (60.7%) were benign, 4 (14.3%) were high-risk and 7 (25.0%) were malignant lesions. The technical success rate was 100% (28/28) for masses and 83.3% (5/6) for non-mass enhancements. Post-clip placement MRI following US-guided biopsy is useful in confirming the adequate sampling of lesions identified on MRI. This method could be an alternative to MRI-guided biopsy for lesions visible on US. • Post-clip MRI is useful for confirming adequate sampling of US-guided biopsy. • Post-clip MRI following US-guided biopsy revealed a 96.6 % technical success rate. • One technical failure case was a benign, 1.1-cm non-mass enhancement. • The technical success rate of US-guided biopsy for non-mass enhancements was 83.3 %.

  12. Mammographic evaluation of suspicious malignant lesions based on ACR(American College of Radiology) breast imaging reporting and data system(BI-RADS)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jei Hee; Oh, Ki Keun; Chang, So Yong; Kim, Eun Kyung; Kim, Mi Hye [Yonsei Univ. College of Medicine, Research Institute of Radiological Science, Yonsei Univ., Seoul (Korea, Republic of)

    1999-12-01

    The purpose of this study was to assess the mammographic features and pathologic outcome of category 4 lesions using the Breast Imaging Reporting and Data System(BI-RADS), and to evaluate the significance of final assessment categories. Using BI-RADS, the interpretations of 8,134 mammograms acquired between January 1997 and May 1998 were categorized. From among 161 lesions categorized as '4' ('suspicious abnormality') and pathologically confirmed by surgery or biopsy, we analysed 113, found in 66 patients. The pathologic outcome of these 113 lesions was as follows:infiltrating ductal carcinoma, 17.7%(20/113); DCIS(ductal carcinoma in sitv), 8.0%(9/113); ADH(atypical ductal hyperplasia), 5.3%(6/113); DEH(ductal epithelial hyperplasia), 1.8%(2/113); ductectasia, 0.9%(1/113), FCD(fibrocystic change), 27.4%(31/113); firoadenoma, 7.1%(8/113); stromal fibrosis, 9.7%(11/113); normal parenchyma, 7.1%(8/113); other pathology, 15.0%(17/113). The most frequent mammographic features of BI-RADS category 4 lesions were irregular mass shape(41.2%), spiculated mass margin(52.3%), amorphous calcification(47.3%) and clustered calcification distribution(37.1%). Because category 4 lesions account for about 25.7% of all breast malignancies, mammographic lesions in this category ('suspicious abnormality') should be considered for supplementary study and breast biopsy rather than short-term follow-up. Initial pathologic findings can thus be confirmed.

  13. "Small intestinal biopsy and anti endomyosial sorologic test in children suspicious for celiac disease: a comparative study in Children Medical Center "

    Directory of Open Access Journals (Sweden)

    F. Mahjoub

    2006-08-01

    Full Text Available Background: Celiac is one the most common causes of malabsorption and is an autoimmune disorder resulting in damage to intestinal epithelial cells by self T lymphocytes. The main culprit is gluten. The aim of our study was to assess the histopathologic findings of patients suspicious to have celiac disease in their first admission and compare them with serologic findings (endomyosial antibody test: EMA. Methods: The study is a prospective descriptional type and 95 patients suspicious to have celiac disease were included who went under upper endoscopy and sampling and also serologic studies. Histopathologic findings were grouped by Marsh classification. Specimens in Marsh stage 0 and 1 were also stained for leukocyte common antigen by immunohistochemistry Results: Ninety five patients, 49 males and 46 females, ranging from 9 months to 17 years (mean: 6.3 ys were included in the study The most common complaint was abdominal pain. EMA test was positive in 43 patients. Most specimens were categorized as Marsh stage IIIA (51 cases by histopatholgic examination, which can be seen in many other conditions. Only 16 patients were categorized as Marsh stage IIIB & IIIC, which are seen in established celiac patients No significant correlation was found between histopathologic and serologic findings. No difference was found between H&E staining and immunohistochemical staining in counting of intra- epithelial lymphocytes. Conclusion: Most of our patients had mild partial villous atrophy which is also seen in many other disorders and also EMA test was negative in this group. It appears that current assessment of celiac disease has many drawbacks and necessity of more specific methods is highly appreciated.

  14. Application of classification trees for the qualitative differentiation of focal liver lesions suspicious for metastasis in gadolinium-EOB-DTPA-enhanced liver MR imaging.

    Science.gov (United States)

    Schelhorn, J; Benndorf, M; Dietzel, M; Burmeister, H P; Kaiser, W A; Baltzer, P A T

    2012-09-01

    To evaluate the diagnostic accuracy of qualitative descriptors alone and in combination for the classification of focal liver lesions (FLLs) suspicious for metastasis in gadolinium-EOB-DTPA-enhanced liver MR imaging. Consecutive patients with clinically suspected liver metastases were eligible for this retrospective investigation. 50 patients met the inclusion criteria. All underwent Gd-EOB-DTPA-enhanced liver MRI (T2w, chemical shift T1w, dynamic T1w). Primary liver malignancies or treated lesions were excluded. All investigations were read by two blinded observers (O1, O2). Both independently identified the presence of lesions and evaluated predefined qualitative lesion descriptors (signal intensities, enhancement pattern and morphology). A reference standard was determined under consideration of all clinical and follow-up information. Statistical analysis besides contingency tables (chi square, kappa statistics) included descriptor combinations using classification trees (CHAID methodology) as well as ROC analysis. In 38 patients, 120 FLLs (52 benign, 68 malignant) were present. 115 (48 benign, 67 malignant) were identified by the observers. The enhancement pattern, relative SI upon T2w and late enhanced T1w images contributed significantly to the differentiation of FLLs. The overall classification accuracy was 91.3 % (O1) and 88.7 % (O2), kappa = 0.902. The combination of qualitative lesion descriptors proposed in this work revealed high diagnostic accuracy and interobserver agreement in the differentiation of focal liver lesions suspicious for metastases using Gd-EOB-DTPA-enhanced liver MRI. © Georg Thieme Verlag KG Stuttgart · New York.

  15. Safe prescribing: a titanic challenge.

    Science.gov (United States)

    Routledge, Philip A

    2012-10-01

    The challenge to achieve safe prescribing merits the adjective 'titanic'. The organisational and human errors leading to poor prescribing (e.g. underprescribing, overprescribing, misprescribing or medication errors) have parallels in the organisational and human errors that led to the loss of the Titanic 100 years ago this year. Prescribing can be adversely affected by communication failures, critical conditions, complacency, corner cutting, callowness and a lack of courage of conviction, all of which were also factors leading to the Titanic tragedy. These issues need to be addressed by a commitment to excellence, the final component of the 'Seven C's'. Optimal prescribing is dependent upon close communication and collaborative working between highly trained health professionals, whose role is to ensure maximum clinical effectiveness, whilst also protecting their patients from avoidable harm. Since humans are prone to error, and the environments in which they work are imperfect, it is not surprising that medication errors are common, occurring more often during the prescribing stage than during dispensing or administration. A commitment to excellence in prescribing includes a continued focus on lifelong learning (including interprofessional learning) in pharmacology and therapeutics. This should be accompanied by improvements in the clinical working environment of prescribers, and the encouragement of a strong safety culture (including reporting of adverse incidents as well as suspected adverse drug reactions whenever appropriate). Finally, members of the clinical team must be prepared to challenge each other, when necessary, to ensure that prescribing combines the highest likelihood of benefit with the lowest potential for harm. © 2012 The Author. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society.

  16. Safe prescribing: a titanic challenge

    Science.gov (United States)

    Routledge, Philip A

    2012-01-01

    The challenge to achieve safe prescribing merits the adjective ‘titanic’. The organisational and human errors leading to poor prescribing (e.g. underprescribing, overprescribing, misprescribing or medication errors) have parallels in the organisational and human errors that led to the loss of the Titanic 100 years ago this year. Prescribing can be adversely affected by communication failures, critical conditions, complacency, corner cutting, callowness and a lack of courage of conviction, all of which were also factors leading to the Titanic tragedy. These issues need to be addressed by a commitment to excellence, the final component of the ‘Seven C's’. Optimal prescribing is dependent upon close communication and collaborative working between highly trained health professionals, whose role is to ensure maximum clinical effectiveness, whilst also protecting their patients from avoidable harm. Since humans are prone to error, and the environments in which they work are imperfect, it is not surprising that medication errors are common, occurring more often during the prescribing stage than during dispensing or administration. A commitment to excellence in prescribing includes a continued focus on lifelong learning (including interprofessional learning) in pharmacology and therapeutics. This should be accompanied by improvements in the clinical working environment of prescribers, and the encouragement of a strong safety culture (including reporting of adverse incidents as well as suspected adverse drug reactions whenever appropriate). Finally, members of the clinical team must be prepared to challenge each other, when necessary, to ensure that prescribing combines the highest likelihood of benefit with the lowest potential for harm. PMID:22738396

  17. Radioactive substance solidifying device

    International Nuclear Information System (INIS)

    Sakoda, Kotaro.

    1979-01-01

    Purpose: To easily solidify radioactive substances adhering to the surfaces of solid wastes without scattering in the circumference by paints, and further to reduce surface contamination concentrations. Constitution: Solid wastes are placed on a hanging plate, and dipped in paints within a paint dipping treatment tank installed at the lower part of a treatment tank by means of a monorail hoist, and the surfaces of said solid wastes are coated with paints, thereby to solidify the radioactivity on the surfaces of the solid wastes. After dipping, the solid wastes are suspended up to a paint spraying tank to dry the paints. After drying, non-contaminated paints are atomized to apply through an atomizing tube onto the solid wastes. After drying the atomized paints, the solid wastes are carried outside the treatment tank by means of the monorail hoist. (Yoshino, Y.)

  18. 75 FR 81536 - Substances Generally Recognized as Safe; Reopening of the Comment Period

    Science.gov (United States)

    2010-12-28

    ... a fundamental truth or proposition on which others depend (Shorter Oxford English Dictionary, 5th... English Dictionary, 5th Edition, 2002); a ``study'' can be defined as the devotion of time and attention...

  19. 76 FR 59247 - Environmental Impact Considerations, Food Additives, and Generally Recognized As Safe Substances...

    Science.gov (United States)

    2011-09-26

    ... agent in the manufacture of silica.'' PART 178--INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND... pale orange or pinkish white powder. * * * * * * * * 0 21. Section 184.1845 is amended by revising the...

  20. Automatic cryogenic liquid level controller is safe for use near combustible substances

    Science.gov (United States)

    Krejsa, M.

    1966-01-01

    Automatic mechanical liquid level controller that is independent of any external power sources is used with safety in the presence of combustibles. A gas filled capillary tube which leads from a pressurized chamber, is inserted into the cryogenic liquid reservoir and becomes a liquid level sensing element or probe.

  1. Landfills as sinks for (hazardous) substances.

    Science.gov (United States)

    Scharff, Heijo

    2012-12-01

    The primary goal of waste regulations is to protect human health and the environment. This requires the removal from the material cycle of those materials that cannot be processed without harm. Policies to promote recycling hold a risk that pollutants are dispersed. Materials have an environmental impact during their entire life cycle from extraction through production, consumption and recycling to disposal. Essentially there are only two routes for pollutants that cannot be rendered harmless: storage in sinks or dispersion into the environment. Many sinks do not contain substances absolutely, but result in slow dispersion. Dispersion leads to exposure and impact to human health and the environment. It is therefore important to assess the impact of the release to the environment. Based on various sources this paper discusses important material flows and their potential impact. This is compared with the intentions and achievements of European environmental and resource policy. The polluter pays principle is being implemented in Europe, but lags behind implementation of waste management regulations. As long as producers are allowed to add hazardous substances to their products and don't take their products back, it is in society's best interest to carefully consider whether recycling or storage in a sink is the better solution. This requires further development of life-cycle assessment tools and harmonization of regulations. In many cases the sink is unavoidable. Landfills as sinks will be needed in the future. Fail-safe design and construction as well as sustainable management of landfills must be further developed.

  2. SAFE/SNAP application to shipboard security

    International Nuclear Information System (INIS)

    Grady, L.M.; Walker, J.L.; Polito, J.

    1981-11-01

    An application of the combined Safeguards Automated Facility Evaluation/Safeguards Network Analysis Procedure (SAFE/SNAP) modeling technique to a physical protection system (PPS) aboard a generic ship is described. This application was performed as an example of how the SAFE and SNAP techniques could be used. Estimates of probability of interruption and neutralization for the example shipboard PPS are provided by SAFE as well as an adversary scenario, which serves as input to SNAP. This adversary scenario is analyzed by SNAP through four cases which incorporate increasingly detailed security force tactics. Comparisons between the results of the SAFE and SNAP analyses are made and conclusions drawn on the validity of each technique. Feedback from SNAP to SAFE is described, and recommendations for upgrading the ship based on the results of the SAFE/SNAP application are also discussed

  3. Safe handling of cytotoxic compounds in a biopharmaceutical environment.

    Science.gov (United States)

    Hensgen, Miriam I; Stump, Bernhard

    2013-01-01

    Handling cytotoxic drugs such as antibody-drug conjugates (ADCs) in a biopharmaceutical environment represents a challenge based on the potency of the compounds. These derivatives are dangerous to humans if they accidentally get in contact with the skin, are inhaled, or are ingested, either as pure compounds in their solid state or as a solution dissolved in a co-solvent. Any contamination of people involved in the manufacturing process has to be avoided. On the other hand, biopharmaceuticals need to be protected simultaneously against any contamination from the manufacturing personnel. Therefore, a tailor-made work environment is mandatory in order to manufacture ADCs. This asks for appropriate technical equipment to keep potential hazardous substances contained. In addition, clearly defined working procedures based on risk assessments as well as proper training for all personnel involved in the manufacturing process are needed to safely handle these highly potent pharmaceuticals.

  4. Stormram 4: An MR Safe Robotic System for Breast Biopsy

    NARCIS (Netherlands)

    Groenhuis, Vincent; Siepel, Françoise Jeanette; Veltman, Jeroen; van Zandwijk, Jordy Kristian; Stramigioli, Stefano

    2018-01-01

    Suspicious lesions in the breast that are only visible on magnetic resonance imaging (MRI) need to be biopsied under MR guidance with high accuracy and efficiency for accurate diagnosis. The aim of this study is to present a novel robotic system, the Stormram 4, and to perform preclinical tests in

  5. Substance Use and Mental Health

    Science.gov (United States)

    ... and Alcohol Tobacco Learn More Substance Use and Mental Health Drugs and Alcohol Did you know that addiction ... Plus – also en Español Treatment Substance Abuse and Mental Health Administration (SAMHSA): SAMHSA’s National Helpline: 1-800-662- ...

  6. Guidelines for safe handling of hazardous drugs: A systematic review.

    Science.gov (United States)

    Bernabeu-Martínez, Mari A; Ramos Merino, Mateo; Santos Gago, Juan M; Álvarez Sabucedo, Luis M; Wanden-Berghe, Carmina; Sanz-Valero, Javier

    2018-01-01

    To review the scientific literature related to the safe handling of hazardous drugs (HDs). Critical analysis of works retrieved from MEDLINE, the Cochrane Library, Scopus, CINHAL, Web of Science and LILACS using the terms "Hazardous Substances", "Antineoplastic Agents" and "Cytostatic Agents", applying "Humans" and "Guidelines" as filters. Date of search: January 2017. In total, 1100 references were retrieved, and from those, 61 documents were selected based on the inclusion and exclusion criteria: 24 (39.3%) documents related to recommendations about HDs; 27 (44.3%) about antineoplastic agents, and 10 (33.3%) about other types of substances (monoclonal antibodies, gene medicine and other chemical and biological agents). In 14 (23.3%) guides, all the stages in the manipulation process involving a risk due to exposure were considered. Only one guide addressed all stages of the handling process of HDs (including stages with and without the risk of exposure). The most described stages were drug preparation (41 guides, 67.2%), staff training and/or patient education (38 guides, 62.3%), and administration (37 guides, 60.7%). No standardized informatics system was found that ensured quality management, traceability and minimization of the risks associated with these drugs. Most of the analysed guidelines limit their recommendations to the manipulation of antineoplastics. The most frequently described activities were preparation, training, and administration. It would be convenient to apply ICTs (Information and Communications Technologies) to manage processes involving HDs in a more complete and simpler fashion.

  7. Virus Alert: Ten Steps to Safe Computing.

    Science.gov (United States)

    Gunter, Glenda A.

    1997-01-01

    Discusses computer viruses and explains how to detect them; discusses virus protection and the need to update antivirus software; and offers 10 safe computing tips, including scanning floppy disks and commercial software, how to safely download files from the Internet, avoiding pirated software copies, and backing up files. (LRW)

  8. Implementation of an Improved Safe Operating Envelope

    International Nuclear Information System (INIS)

    Prime, Robyn; McIntyre, Mark; Reeves, David

    2008-01-01

    This paper is a continuation of the paper presented at IYNC 2004 on 'The Definition of a Safe Operating Envelope'. The current paper concentrates on the implementation process of the Safe Operating Envelope employed at the Point Lepreau Generating Station. (authors)

  9. Creating Safe Spaces for Music Learning

    Science.gov (United States)

    Hendricks, Karin S.; Smith, Tawnya D.; Stanuch, Jennifer

    2014-01-01

    This article offers a practical model for fostering emotionally safe learning environments that instill in music students a positive sense of self-belief, freedom, and purpose. The authors examine the implications for music educators of creating effective learning environments and present recommendations for creating a safe space for learning,…

  10. Implementation of an Improved Safe Operating Envelope

    Energy Technology Data Exchange (ETDEWEB)

    Prime, Robyn; McIntyre, Mark [NB Power Nuclear, P.O. Box 600, Lepreau, NB (Canada); Reeves, David [Atlantic Nuclear Services Ltd., PO Box 1268 Fredericton, NB (Canada)

    2008-07-01

    This paper is a continuation of the paper presented at IYNC 2004 on 'The Definition of a Safe Operating Envelope'. The current paper concentrates on the implementation process of the Safe Operating Envelope employed at the Point Lepreau Generating Station. (authors)

  11. Radioiodination of humic substances

    Energy Technology Data Exchange (ETDEWEB)

    Franke, K.; Kupsch, H. [Inst. of Interdisciplinary Isotope Research, Leipzig (Germany)

    2010-07-01

    The known IODO-GEN trademark -method was adapted for radiolabeling of humic and fulvic acids with {sup 131}I. The water insoluble oxidizing agent 1,3,4,6tetrachloro-3{alpha},6{alpha}-diphenylglycoluril (IODO-GEN trademark) forms an iodous ion species (I{sup +}), which undergoes an electrophilic I/H-substitution on aromatic moieties of the humic and fulvic acids. This method offers mild conditions with a lesser extent of oxidative alterations of the target molecule, accompanied by an easy handling due to the virtual water-insolubility of the oxidizing agent. The method was optimized and different techniques were tested for the purification of the radioiodinated humic material. The yield of the labeling procedure varies between 45 and 75% depending on the provenance of the humic material and the applied purification method. A specific activity up to 40 MBq/mg was achieved. Furthermore, the known inherent photo-susceptibility of the iodinated humic substance and the influence of reducing agents were verified. An additional release of {sup 131}I up to 20% and up to 35%, respectively were observed. (orig.)

  12. Distillation of bituminous substances

    Energy Technology Data Exchange (ETDEWEB)

    du Buisson, M A.B.B.

    1845-06-23

    New and improved methods are described for the distillation of bituminous schistus and other bituminous substances, as well as for the purification, rectification, and preparation necessary for the employment of the productions obtained by such distillation for various useful purposes. This invention consists, first, in the arrangement and construction of furnace or apparatus for the distillation of schistus, and (any) other bituminous rocks. This furnace is made of circular brick-work, and is provided with the requisite number of fires placed round the circumference. The retort is of a conical or funnel shape, and when ready for use, has the appearance of one inverted cone being placed within a larger cone, in such a manner as to leave a space between the two cones for the reception of the schistus. Both cones are capable of being closed at their apexes, and their mouths, which are placed upwards, are connected together, and hermetically closed by a flat ring. The flame draft is caused to impinge against the lower portion of the outer cone and ascending, turns over the upper edge and descends within the inner cone to the mouth of the chimney, which is placed in the interior, and as low as may be convenient. A third cone is so placed within the inner cone as to cause the flame draft, in its descent, to bind against the surface of the retort.

  13. Environmentally safe system for treatment of bio corrosion of ETICS

    Directory of Open Access Journals (Sweden)

    Minarovičová Katarína

    2018-01-01

    Full Text Available Effects of microorganisms on building facades are responsible for aesthetic, bio-geophysical and biogeochemical deterioration. The process of cleaning of contaminated facades involves the removal and eradication of micro flora on the surface of insulation using chemical products, killing cells and eliminating all living mass, including organic ingredients. The removal of bio corrosion coating from ETICS structure by means of chemical and preservative substances (biocides is currently the only effective and most used technology. Uncontrolled leaching of the used biocides is unacceptable. Meantime, new technology for environmentally safe maintenance of ETICS is needed. Scientists have been working on replacement the biocides currently used in facades treatment with eco-friendly biocides that have no negative effects on the environment or human beings. While the eco- treatment will be available, safe dewatering of chemicals being leached from the surface of the facade could be provided by e.g. special drain systems adjusted to the building type, use and age. The paper gives an overview of the problem in context of Slovakia and examples of leaching systems designed for new and renovated buildings.

  14. Segmental resection with primary anastomosis is not always safe in splenic flexure perforation.

    Science.gov (United States)

    Weledji, Elroy P; Mokake, Martin D; Sinju, Motaze

    2016-01-16

    Familial adenomatous polyposis (FAP) is caused by a rare mutation of the adenomatous polyposis coli gene on Chromosome 5q. The risk of colorectal cancer in patients with FAP is nearly 100% and intensive endoscopic surveillance or prophylactic colectomy are mandatory. If extensive endoscopic surveillance is chosen, there is a cumulative risk of perforation and bleeding especially after polypectomy. We discussed the problems and options in the management of the late diagnosis of an iatrogenic perforation of the splenic flexure complicating endoscopic surveillance in FAP. We present a 35-year-old black African man with FAP who sustained a splenic flexure perforation following a colonoscopic polypectomy of a suspicious lesion. He underwent a splenic flexure resection and primary anastomosis that dehisced and the patient benefited from an emergency definitive colectomy and ileorectal anastomosis. Resection with primary anastomosis following iatrogenic perforation of the splenic flexure is not safe because of a high chance of anastomotic dehiscence. Following a late diagnosis in an unstable patient exteriorization of the perforation as a stoma is a better option prior to a definitive prophylactic colectomy.

  15. A method and apparatus for preparing the storage of noxious substances, in particular radioactive substances

    International Nuclear Information System (INIS)

    1974-01-01

    The invention relates to the storage of radioactive substances. It deals with a method for storing a substance, in particular a noxious or radioactive substance, comprising trapping said substance in a solid substance by bombarding said solid substance with ions of the above substance, so that the latter reaches a certain concentration level in the solid substance. This is applicable to the storage of radioactive wastes [fr

  16. Pregnancy and Fish: What's Safe to Eat?

    Science.gov (United States)

    ... or planning to become pregnant. If you regularly eat fish high in mercury, the substance can accumulate in your bloodstream over time. Too much mercury in your bloodstream could damage your baby's developing brain and nervous system. The Food and ...

  17. Alexithymia in Egyptian Substance Abusers.

    Science.gov (United States)

    El Rasheed, Amany Haroun

    2001-03-01

    Alexithymia is thought of as a trait that predisposes to drug abuse. Moreover, it is suggested to be related to type of the substance abused, with the worst-case scenario including a worse prognosis as well as tendency to relapse or even not to seek treatment at all. To address this important subject in Egyptian patients, a sample of 200 Egyptian substance abusers was randomly selected from inpatients in the Institute of Psychiatry, Ain Shams University, Egypt. The study also included 200 group-matched controls. DSM-IV criteria were used for assessment of substance use disorders, and toxicologic urine analysis was used to confirm the substances of abuse. Toronto Alexithymia Scale (TAS)-Arabic version was used for assessment of alexithymia. It was found that alexithymia was significantly more prevalent in the substance use disorders group as compared to healthy controls. It was also found that among the substance use disorders group, alexithymics reported more polysubstance abuse, more opiate use (other than heroin IV), lower numbers of hospitalizations, lower numbers of reported relapses, and a lower tendency to relapse as a result of internal cues compared to patients without alexithymia. Statistically significant associations were also found between alexithymia and more benzodiazepine abuse and nonpersistence in treatment. The results suggest that alexithymia should be targeted in a treatment setting for substance use disorders.

  18. Definition of Substance and Non-substance Addiction.

    Science.gov (United States)

    Zou, Zhiling; Wang, Huijun; d'Oleire Uquillas, Federico; Wang, Xiaomei; Ding, Jianrui; Chen, Hong

    2017-01-01

    Substance addiction (or drug addiction) is a neuropsychiatric disorder characterized by a recurring desire to continue taking the drug despite harmful consequences. Non-substance addiction (or behavioral addiction) covers pathological gambling, food addiction, internet addiction, and mobile phone addiction. Their definition is similar to drug addiction but they differ from each other in specific domains. This review aims to provide a brief overview of past and current definitions of substance and non-substance addiction, and also touches on the topic of diagnosing drug addiction and non-drug addiction, ultimately aiming to further the understanding of the key concepts needed for a foundation to study the biological and psychological underpinnings of addiction disorders.

  19. Agreement Among RTOG Sarcoma Radiation Oncologists in Contouring Suspicious Peritumoral Edema for Preoperative Radiation Therapy of Soft Tissue Sarcoma of the Extremity

    Energy Technology Data Exchange (ETDEWEB)

    Bahig, Houda [Department of Radiation Oncology, Centre Hospitalier de l' Université de Montréal, Montreal, QC (Canada); Roberge, David, E-mail: david.roberge.chum@ssss.gouv.qc.ca [Department of Radiation Oncology, Centre Hospitalier de l' Université de Montréal, Montreal, QC (Canada); Bosch, Walter [Department of Radiation Oncology, Washington University, St Louis, Missouri (United States); Levin, William [Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania (United States); Petersen, Ivy; Haddock, Michael [Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota (United States); Freeman, Carolyn [Division of Radiation Oncology, McGill University Health Centre, Montreal, QC (Canada); DeLaney, Thomas F. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Abrams, Ross A. [Department of Radiation Oncology, Rush University Medical Center, Chicago, Illinois (United States); Indelicato, Danny J. [Department of Radiation Oncology, University of Florida Medical Center, Jacksonville, Florida (United States); Baldini, Elizabeth H. [Department of Radiation Oncology, Brigham and Women' s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts (United States); Hitchcock, Ying [Department of Radiation Oncology, University of Utah Medical Center, Salt Lake City, Utah (United States); Kirsch, David G. [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Kozak, Kevin R. [Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (United States); Wolfson, Aaron [Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida (United States); and others

    2013-06-01

    Purpose: Peritumoral edema may harbor sarcoma cells. The extent of suspicious edema (SE) included in the treatment volume is subject to clinical judgment, balancing the risk of missing tumor cells with excess toxicity. Our goal was to determine variability in SE delineation by sarcoma radiation oncologists (RO). Methods and Materials: Twelve expert ROs were provided with T1 gadolinium and T2-weighted MR images of 10 patients with high-grade extremity soft-tissue sarcoma. Gross tumor volume, clinical target volume (CTV)3cm (3 cm longitudinal and 1.5 cm radial margin), and CTV2cm (2 cm longitudinal and 1 cm radial margin) were contoured by a single observer. Suspicious peritumoral edema, defined as abnormal signal on T2 images, was independently delineated by all 12 ROs. Contouring agreement was analyzed using the simultaneous truth and performance level estimation (STAPLE) algorithm and kappa statistics. Results: The mean volumes of GTV, CTV2cm, and CTV3cm were, respectively, 130 cm{sup 3} (7-413 cm{sup 3}), 280 cm{sup 3} and 360 cm{sup 3}. The mean consensus volume computed using the STAPLE algorithm at 95% confidence interval was 188 cm{sup 3} (24-565 cm{sup 3}) with a substantial overall agreement corrected for chance (mean kappa = 0.71; range: 0.32-0.87). The minimum, maximum, and mean volume of SE (excluding the GTV) were 4, 182, and 58 cm{sup 3} (representing a median of 29% of the GTV volume). The median volume of SE not included in the CTV2cm and in the CTV3cm was 5 and 0.3 cm{sup 3}, respectively. There were 3 large tumors with >30 cm{sup 3} of SE not included in the CTV3cm volume. Conclusion: Despite the fact that SE would empirically seem to be a more subjective volume, a substantial or near-perfect interobserver agreement was observed in SE delineation in most cases with high-grade soft-tissue sarcomas of the extremity. A median of 97% of the consensus SE is within the CTV2cm (99.8% within the CTV3cm). In a minority of cases, however, significant

  20. Agreement among RTOG sarcoma radiation oncologists in contouring suspicious peritumoral edema for preoperative radiation therapy of soft tissue sarcoma of the extremity.

    Science.gov (United States)

    Bahig, Houda; Roberge, David; Bosch, Walter; Levin, William; Petersen, Ivy; Haddock, Michael; Freeman, Carolyn; Delaney, Thomas F; Abrams, Ross A; Indelicato, Danny J; Baldini, Elizabeth H; Hitchcock, Ying; Kirsch, David G; Kozak, Kevin R; Wolfson, Aaron; Wang, Dian

    2013-06-01

    Peritumoral edema may harbor sarcoma cells. The extent of suspicious edema (SE) included in the treatment volume is subject to clinical judgment, balancing the risk of missing tumor cells with excess toxicity. Our goal was to determine variability in SE delineation by sarcoma radiation oncologists (RO). Twelve expert ROs were provided with T1 gadolinium and T2-weighted MR images of 10 patients with high-grade extremity soft-tissue sarcoma. Gross tumor volume, clinical target volume (CTV)3cm (3 cm longitudinal and 1.5 cm radial margin), and CTV2cm (2 cm longitudinal and 1 cm radial margin) were contoured by a single observer. Suspicious peritumoral edema, defined as abnormal signal on T2 images, was independently delineated by all 12 ROs. Contouring agreement was analyzed using the simultaneous truth and performance level estimation (STAPLE) algorithm and kappa statistics. The mean volumes of GTV, CTV2cm, and CTV3cm were, respectively, 130 cm(3) (7-413 cm(3)), 280 cm(3) and 360 cm(3). The mean consensus volume computed using the STAPLE algorithm at 95% confidence interval was 188 cm(3) (24-565 cm(3)) with a substantial overall agreement corrected for chance (mean kappa = 0.71; range: 0.32-0.87). The minimum, maximum, and mean volume of SE (excluding the GTV) were 4, 182, and 58 cm(3) (representing a median of 29% of the GTV volume). The median volume of SE not included in the CTV2cm and in the CTV3cm was 5 and 0.3 cm(3), respectively. There were 3 large tumors with >30 cm(3) of SE not included in the CTV3cm volume. Despite the fact that SE would empirically seem to be a more subjective volume, a substantial or near-perfect interobserver agreement was observed in SE delineation in most cases with high-grade soft-tissue sarcomas of the extremity. A median of 97% of the consensus SE is within the CTV2cm (99.8% within the CTV3cm). In a minority of cases, however, significant expansion of the CTVs is required to cover SE. Copyright © 2013 Elsevier Inc. All rights

  1. Agreement Among RTOG Sarcoma Radiation Oncologists in Contouring Suspicious Peritumoral Edema for Preoperative Radiation Therapy of Soft Tissue Sarcoma of the Extremity

    International Nuclear Information System (INIS)

    Bahig, Houda; Roberge, David; Bosch, Walter; Levin, William; Petersen, Ivy; Haddock, Michael; Freeman, Carolyn; DeLaney, Thomas F.; Abrams, Ross A.; Indelicato, Danny J.; Baldini, Elizabeth H.; Hitchcock, Ying; Kirsch, David G.; Kozak, Kevin R.; Wolfson, Aaron

    2013-01-01

    Purpose: Peritumoral edema may harbor sarcoma cells. The extent of suspicious edema (SE) included in the treatment volume is subject to clinical judgment, balancing the risk of missing tumor cells with excess toxicity. Our goal was to determine variability in SE delineation by sarcoma radiation oncologists (RO). Methods and Materials: Twelve expert ROs were provided with T1 gadolinium and T2-weighted MR images of 10 patients with high-grade extremity soft-tissue sarcoma. Gross tumor volume, clinical target volume (CTV)3cm (3 cm longitudinal and 1.5 cm radial margin), and CTV2cm (2 cm longitudinal and 1 cm radial margin) were contoured by a single observer. Suspicious peritumoral edema, defined as abnormal signal on T2 images, was independently delineated by all 12 ROs. Contouring agreement was analyzed using the simultaneous truth and performance level estimation (STAPLE) algorithm and kappa statistics. Results: The mean volumes of GTV, CTV2cm, and CTV3cm were, respectively, 130 cm 3 (7-413 cm 3 ), 280 cm 3 and 360 cm 3 . The mean consensus volume computed using the STAPLE algorithm at 95% confidence interval was 188 cm 3 (24-565 cm 3 ) with a substantial overall agreement corrected for chance (mean kappa = 0.71; range: 0.32-0.87). The minimum, maximum, and mean volume of SE (excluding the GTV) were 4, 182, and 58 cm 3 (representing a median of 29% of the GTV volume). The median volume of SE not included in the CTV2cm and in the CTV3cm was 5 and 0.3 cm 3 , respectively. There were 3 large tumors with >30 cm 3 of SE not included in the CTV3cm volume. Conclusion: Despite the fact that SE would empirically seem to be a more subjective volume, a substantial or near-perfect interobserver agreement was observed in SE delineation in most cases with high-grade soft-tissue sarcomas of the extremity. A median of 97% of the consensus SE is within the CTV2cm (99.8% within the CTV3cm). In a minority of cases, however, significant expansion of the CTVs is required to cover SE

  2. Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP).

    Science.gov (United States)

    Strickland, Kyle C; Eszlinger, Markus; Paschke, Ralf; Angell, Trevor E; Alexander, Erik K; Marqusee, Ellen; Nehs, Matthew A; Jo, Vickie Y; Lowe, Alarice; Vivero, Marina; Hollowell, Monica; Qian, Xiaohua; Wieczorek, Tad; French, Christopher A; Teot, Lisa A; Cibas, Edmund S; Lindeman, Neal I; Krane, Jeffrey F; Barletta, Justine A

    2018-03-01

    Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is an indolent thyroid tumor characterized by frequent RAS mutations and an absence of the BRAF V600E mutation commonly seen in classical papillary thyroid carcinoma (cPTC). The ability to differentiate potential NIFTP/follicular variant of papillary thyroid carcinoma (FVPTC) from cPTC at the time of fine-needle aspiration (FNA) can facilitate conservative management of NIFTP. The aim of the current study was to investigate how molecular testing may add to cytologic assessment in the pre-operative differentiation of potential NIFTP/FVPTC and cPTC. We had previously evaluated cytologists' ability to prospectively distinguish potential NIFTP/FVPTC from cPTC in a cohort of 56 consecutive FNAs diagnosed as malignant or suspicious for malignancy. We utilized this cohort to perform molecular analysis. Detected molecular abnormalities were stratified into two groups: (1) those supporting malignancy and (2) those supporting a diagnosis of potential NIFTP/FVPTC. The cytologists' characterization of cases and the detected molecular alterations were correlated with the final histologic diagnoses. Molecular testing was performed in 52 (93%) of the 56 cases. For the 37 cases cytologists favored to be cPTC, 31 (84%) had a molecular result that supported malignancy (28 BRAF V600E mutations, 2 NTRK1 fusions, 1 AGK-BRAF fusion). For the 8 cases that were favored to be NIFTP/FVPTC by cytologists, 7 (88%) had a molecular result that supported conservative management (1 NRAS mutation, 6 wild-type result). Seven cases were designated as cytomorphologically indeterminate for NIFTP/FVPTC or cPTC, of which 6 (86%) had a molecular result that would have aided in the pre-operative assessment of potential NIFTP/FVPTC or cPTC/malignancy. These included 3 BRAF V600E mutations in nodules that were cPTC on resection, an HRAS mutation, and a wild-type result in the 2 nodules that were NIFTP, and a TERT promoter

  3. Stroke And Substance Abuse

    Directory of Open Access Journals (Sweden)

    A Chitsaz

    2017-02-01

    Full Text Available Introduction: stroke in recreational substance users can be an indirect complication, like endocarditis and cardio embolism in parenteral drug users. With some drug like cocaine, stroke appear to be the result of a direct effect. In young subjects without other risk factors provide persuasive evidence for causality . OPIATES: Heroine is the most abused opiate drug, which is administered by injection, by snorting or by smoking. Stroke affects heroin users by diverse mechanisms,. Injectors are at risk of infections endocarditis, which carries risk for both ischemic and hemorrhagic stroke. Cerebral or subarachnoid hemorrhage usually occurs after rupture of a septic (mycotic aneurysm. Heroine users can are also at risk for hemorrhagic stroke secondary to liver failure with deranged clotting and to heroin nephropathy with uremia or malignant hypertension. In some heroin users the drug it self is directly causal due to vasculitis, hypersensitivity and immunologic changes. Embolization of foreign material to brain due to mixed of heroine with quinine can cause cerebral embolism. AMPHETAMINE AND other psychostimulants: In abuser of amphetamine hemorrhagic stroke can occur, oral, intravenous, nasal, and inhalational routes of administration have been reported. Most were chronic user, but in several patients, stroke followed a first exposure. Some of amphetamine induced intracranial hemorrhages are secondary to acute hypertension, some to cerebral vacuities, and some to a combination of two. Decongestants and diet pills: Phenylpropanolamine (PPA, an amphetamine – like drug, in decongestants and diet pills, induce acute hypertension, sever headache, psychiatric symptoms, seizures and hemorrhagic stroke. Ephedrine and pseudo ephedrine are present in decongestants and bronchodilators and induce headache, tachyarrhythmia, hypertensive emergency, and hemorrhagic and occlusive stroke. Ecstasy, 3,4 Methylenedioxymethamphetamin (MDMA with amphetamine like can

  4. Guide for the realization of core needle biopsy through stereotaxy in the diagnosis of suspicious breast lesions of malignity

    International Nuclear Information System (INIS)

    Jimenez Zuniga, Jorge Luis

    2012-01-01

    according to the type of radiological image and significantly major when injuries have presented nodules with microcalcifications or increases of density, and has been significantly lower when the form of presentation consist of isolated microcalcifications. The CNB guided by stereotaxy has been a valid technique regardless the type of radiological image that has presented the lesion. The stereotaxy has been a useful method, safe, accurate and almost without complications for the realization of core needle biopsies and preoperative locations, in order to make a diagnosis of the lesion or to obtain histological material for study of receptors in those malignant lesions before neoadjuvant treatment. The elaboration of the protocols for the realization of the breast biopsies, guided by stereotaxy, has been very useful to unify the criteria of the management of breast lesions, both for physicians responsible of the primary care, as well as for specialists responsible of the management, treatment and monitoring of patients [es

  5. InaSAFE applications in disaster preparedness

    Science.gov (United States)

    Pranantyo, Ignatius Ryan; Fadmastuti, Mahardika; Chandra, Fredy

    2015-04-01

    Disaster preparedness activities aim to reduce the impact of disasters by being better prepared to respond when a disaster occurs. In order to better anticipate requirements during a disaster, contingency planning activities can be undertaken prior to a disaster based on a realistic disaster scenario. InaSAFE is a tool that can inform this process. InaSAFE is a free and open source software that estimates the impact to people and infrastructure from potential hazard scenarios. By using InaSAFE, disaster managers can develop scenarios of disaster impacts (people and infrastructures affected) to inform their contingency plan and emergency response operation plan. While InaSAFE provides the software framework exposure data and hazard data are needed as inputs to run this software. Then InaSAFE can be used to forecast the impact of the hazard scenario to the exposure data. InaSAFE outputs include estimates of the number of people, buildings and roads are affected, list of minimum needs (rice and clean water), and response checklist. InaSAFE is developed by Indonesia's National Disaster Management Agency (BNPB) and the Australian Government, through the Australia-Indonesia Facility for Disaster Reduction (AIFDR), in partnership with the World Bank - Global Facility for Disaster Reduction and Recovery (GFDRR). This software has been used in many parts of Indonesia, including Padang, Maumere, Jakarta, and Slamet Mountain for emergency response and contingency planning.

  6. The BMC ACCESS project: the development of a medically enhanced safe haven shelter.

    Science.gov (United States)

    Lincoln, Alisa; Johnson, Peggy; Espejo, Dennis; Plachta-Elliott, Sara; Lester, Peggy; Shanahan, Christopher; Abbott, Susan; Cabral, Howard; Jamanka, Amber; Delman, Jonathan; Kenny, Patty

    2009-10-01

    This paper describes the development and implementation of the Boston Medical Center (BMC) Advanced Clinical Capacity for Engagement, Safety, and Services Project. In October 2002, the BMC Division of Psychiatry became the first such entity to open a Safe Haven shelter for people who are chronically homeless, struggling with severe mental illness, and actively substance abusing. The low-demand Safe Haven model targets the most difficult to reach population and serves as a "portal of entry" to the mental health and addiction service systems. In this paper, the process by which this blended funded, multi-level collaboration, consisting of a medical center, state, city, local, and community-based consumer organizations, was created and is maintained, as well as the clinical model of care is described. Lessons learned from creating the Safe Haven Shelter and the development and implementation of the consumer-informed evaluation are discussed as well as implications for future work with this population.

  7. Ozone-depleting Substances (ODS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This site includes all of the ozone-depleting substances (ODS) recognized by the Montreal Protocol. The data include ozone depletion potentials (ODP), global warming...

  8. Dermal uptake of petroleum substances

    NARCIS (Netherlands)

    Jakasa, Ivone; Kezic, Sanja; Boogaard, Peter J.

    2015-01-01

    Petroleum products are complex substances comprising varying amounts of linear and branched alkanes, alkenes, cycloalkanes, and aromatics which may penetrate the skin at different rates. For proper interpretation of toxic hazard data, understanding their percutaneous absorption is of paramount

  9. Safe actinide disposition in molten salt reactors

    International Nuclear Information System (INIS)

    Gat, U.

    1997-01-01

    Safe molten salt reactors (MSR) can readily accommodate the burning of all fissile actinides. Only minor compromises associated with plutonium are required. The MSRs can dispose safely of actinides and long lived isotopes to result in safer and simpler waste. Disposing of actinides in MSRs does increase the source term of a safety optimized MSR. It is concluded that the burning and transmutation of actinides in MSRs can be done in a safe manner. Development is needed for the processing to handle and separate the actinides. Calculations are needed to establish the neutron economy and the fuel management. 9 refs

  10. Treating Substance-Using Women and Their Children in Public Housing: Preliminary Evaluation Findings.

    Science.gov (United States)

    Metsch, Lisa R.; Wolfe, Harlan P.; Fewell, Rebecca; McCoy, Clyde B.; Elwood, William N.; Wohler-Torres, Brad; Petersen-Baston, Pamela; Haskins, Henry V.

    2001-01-01

    SafePort is a residential substance abuse treatment program within public housing to provide drug treatment to parenting women in Key West, Florida. All family members--women, children, and significant others--receive comprehensive assessments to determine appropriate therapeutic interventions. Preliminary evaluation findings suggest that women…

  11. Substances of very high concern and the transition to a circular economy : An initial inventory

    NARCIS (Netherlands)

    Wassenaar PNH; Janssen N; de Poorter LRM; Bodar CWM; VSP; MSP

    2017-01-01

    Reuse and recycling of products are key elements in a circular economy. This exploratory RIVM study shows that a great number of waste streams may contain various substances of very high concern (ZZS), which may hamper safe recycling options in the Netherlands. RIVM recommends an adequate risk

  12. Jumping to Conclusions Is Associated with Paranoia but Not General Suspiciousness: A Comparison of Two Versions of the Probabilistic Reasoning Paradigm

    Directory of Open Access Journals (Sweden)

    Steffen Moritz

    2012-01-01

    Full Text Available Theoretical models ascribe jumping to conclusions (JTCs a prominent role in the pathogenesis of paranoia. While many earlier studies corroborated this account, some newer investigations have found no or only small associations of the JTC bias with paranoid symptoms. The present study examined whether these inconsistencies in part reflect methodological differences across studies. The study was built upon the psychometric high-risk paradigm. A total of 1899 subjects from the general population took part in an online survey and were administered the Paranoia Checklist as well as one of two different variants of the probabilistic reasoning task: one variant with a traditional instruction (a and one novel variant that combines probability estimates with decision judgments (b. Factor analysis of the Paranoia Checklist yielded an unspecific suspiciousness factor and a psychotic paranoia factor. The latter was significantly associated with scores indicating hasty decision making. Subjects scoring two standard deviations above the mean of the Paranoia Checklist showed an abnormal data-gathering style relative to subjects with normal scores. Findings suggest that the so-called decision threshold parameter is more sensitive than the conventional JTC index. For future research the specific contents of paranoid beliefs deserve more consideration in the investigation of decision making in schizophrenia as JTC seems to be associated with core psychosis-prone features of paranoia only.

  13. Project SAFE. Complexing agents in SFR

    Energy Technology Data Exchange (ETDEWEB)

    Fanger, G.; Skagius, K.; Wiborgh, M. [Kemakta Konsult AB, Stockholm (Sweden)

    2001-01-01

    Low- and intermediate level radioactive waste, produced at Swedish nuclear power plants, will be deposited in an underground repository, SFR. Different substances in the waste or in degradation products emanating from the waste, and chemicals added during the building of cementitious barriers in the repository, may exhibit complexing properties. The complexation of radionuclides with such ligands may increase the mobility of the deposited radionuclides as sorption on the cement phases is decreased and solubility increased. This could lead to an increased leaching of the radionuclides from the repository to the geosphere and biosphere. To be able to evaluate the implications for the function and long-term safety of the repository a study has been performed on complexants in SFR. The study is a part of project SAFE (Safety Assessment of Final Repository for operational Radioactive Waste) at the Swedish Nuclear Fuel and Waste Management Co, SKB. Concentrations of complexants were calculated in different waste types in the repository and compared to critical levels above which radionuclide sorption may be affected. The analysis is based on recent research presented in international and national literature sources. The waste in SFR that may act or give rise to substances with complexing properties mainly consists of cellulose materials, including cement additives used in waste conditioning and backfill grout. The radioactive waste also contains chemicals mainly used in decontamination processes at the nuclear power plants, e.g. EDTA, NTA, gluconate, citric acid and oxalic acid. The calculations performed in this report show that the presence of complexants in SFR may lead to a sorption reduction for some radionuclides in certain waste types. This may have to be considered when performing calculations of the radionuclide transport. Concentration calculations of isosaccharinic acid (ISA), using a degradation yield of 0.1 mole/kg cellulose (2%), showed that the limit above

  14. Project SAFE. Complexing agents in SFR

    International Nuclear Information System (INIS)

    Fanger, G.; Skagius, K.; Wiborgh, M.

    2001-01-01

    Low- and intermediate level radioactive waste, produced at Swedish nuclear power plants, will be deposited in an underground repository, SFR. Different substances in the waste or in degradation products emanating from the waste, and chemicals added during the building of cementitious barriers in the repository, may exhibit complexing properties. The complexation of radionuclides with such ligands may increase the mobility of the deposited radionuclides as sorption on the cement phases is decreased and solubility increased. This could lead to an increased leaching of the radionuclides from the repository to the geosphere and biosphere. To be able to evaluate the implications for the function and long-term safety of the repository a study has been performed on complexants in SFR. The study is a part of project SAFE (Safety Assessment of Final Repository for operational Radioactive Waste) at the Swedish Nuclear Fuel and Waste Management Co, SKB. Concentrations of complexants were calculated in different waste types in the repository and compared to critical levels above which radionuclide sorption may be affected. The analysis is based on recent research presented in international and national literature sources. The waste in SFR that may act or give rise to substances with complexing properties mainly consists of cellulose materials, including cement additives used in waste conditioning and backfill grout. The radioactive waste also contains chemicals mainly used in decontamination processes at the nuclear power plants, e.g. EDTA, NTA, gluconate, citric acid and oxalic acid. The calculations performed in this report show that the presence of complexants in SFR may lead to a sorption reduction for some radionuclides in certain waste types. This may have to be considered when performing calculations of the radionuclide transport. Concentration calculations of isosaccharinic acid (ISA), using a degradation yield of 0.1 mole/kg cellulose (2%), showed that the limit above

  15. Serum Müllerian inhibiting substance levels are lower in premenopausal women with breast precancer and cancer

    Directory of Open Access Journals (Sweden)

    Sticca Robert

    2011-05-01

    Full Text Available Abstract Background In preclinical studies, müllerian inhibiting substance (MIS has a protective affect against breast cancer. Our objective was to determine whether serum MIS concentrations were associated with cancerous or precancerous lesions. Blood from 30 premenopausal women was collected and serum extracted prior to their undergoing breast biopsy to assess a suspicious lesion found on imaging or physical examination. Based on biopsy results, the serum specimens were grouped as cancer (invasive or ductal carcinoma in situ, precancer (atypical hyperplasia or lobular carcinoma in situ, or benign. Findings Serum from women with cancer and precancer (p = .0009 had lower MIS levels than serum from women with benign disease. Conclusion Our findings provide preliminary evidence for MIS being associated with current breast cancer risk, which should be validated in a larger population.

  16. Staying Safe on Social Network Sites

    Science.gov (United States)

    ... Tips Security Tip (ST06-003) Staying Safe on Social Networking Sites Original release date: January 26, 2011 | Last revised: ... so you should take certain precautions. What are social networking sites? Social networking sites, sometimes referred to as "friend- ...

  17. Implicit attitudes towards risky and safe driving

    DEFF Research Database (Denmark)

    Martinussen, Laila Marianne; Sømhovd, Mikael Julius; Møller, Mette

    ; further, self-reports of the intention to drive safely (or not) are socially sensitive. Therefore, we examined automatic preferences towards safe and risky driving with a Go/No-go Association Task (GNAT). The results suggest that (1) implicit attitudes towards driving behavior can be measured reliably...... with the GNAT; (2) implicit attitudes towards safe driving versus towards risky driving may be separable constructs. We propose that research on driving behavior may benefit from routinely including measures of implicit cognition. A practical advantage is a lesser susceptibility to social desirability biases......, compared to self-report methods. Pending replication in future research, the apparent dissociation between implicit attitudes towards safe versus risky driving that we observed may contribute to a greater theoretical understanding of the causes of unsafe and risky driving behavior....

  18. High-Protein Diets: Are They Safe?

    Science.gov (United States)

    Healthy Lifestyle Nutrition and healthy eating Are high-protein diets safe for weight loss? Answers from Katherine ... L.D. For most healthy people, a high-protein diet generally isn't harmful, particularly when followed ...

  19. Safe delivery, Service utilization, Metekel Zone

    African Journals Online (AJOL)

    decision making power of subjects were found to have a statistically significant association with preference of safe delivery ... Studies that focused on maternal mortality and proportion of ...... Anna M, Hannekee M, Frank Odhiambo et.al. Use.

  20. The safe transport of radioactive materials

    International Nuclear Information System (INIS)

    Messenger, W. de L.M.

    1979-02-01

    The hazards of radioactive materials in transport are surveyed. The system whereby they are safely transported between nuclear establishments in the United Kingdom and overseas is outlined. Several popular misconceptions are dealt with. (author)

  1. Layered Safe Motion Planning for Autonomous Vehicles.

    Science.gov (United States)

    1995-09-01

    The major problem addressed by this research is how to plan a safe motion for autonomous vehicles in a two dimensional, rectilinear world. With given start and goal configurations, the planner performs motion planning which

  2. AFSC/REFM: Groundfish SAFE Economic Report

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Groundfish SAFE Economic Report, published annually as a supplement to the Stock Assessment and Fishery Evaluation Reports for Bering Sea and Aleutian Islands...

  3. Think Before You Ink: Are Tattoos Safe?

    Science.gov (United States)

    ... Consumers Consumer Updates Think Before You Ink: Are Tattoos Safe? Share Tweet Linkedin Pin it More sharing ... I be concerned about unsafe practices, or the tattoo ink itself? Both. While you can get serious ...

  4. Safe Eats - Eating Out and Bringing In

    Science.gov (United States)

    ... to stay safe. What's On the Menu? When dining out: Remember that harmful bacteria can be hidden ... above the "danger zone." Remember the 2-Hour Rule : Discard any perishables (foods that can spoil or ...

  5. Safeguards Automated Facility Evaluation (SAFE) methodology

    International Nuclear Information System (INIS)

    Chapman, L.D.; Grady, L.M.; Bennett, H.A.; Sasser, D.W.; Engi, D.

    1978-01-01

    The SAFE procedure is an efficient method of evaluating the physical protection system of a nuclear facility. Since the algorithms used in SAFE for path generation and evaluation are analytical, many paths can be evaluated with a modest investment in computer time. SAFE is easy to use because the information required is well-defined and the interactive nature of this procedure lends itself to straightforward operation. The modular approach that has been taken allows other functionally equivalent modules to be substituted as they become available. The SAFE procedure has broad applications in the nuclear facility safeguards field as well as in the security field in general. Any fixed facility containing valuable materials or components to be protected from theft or sabotage could be analyzed using this same automated evaluation technique

  6. SAFE users manual. Volume 4. Computer programs

    International Nuclear Information System (INIS)

    Grady, L.M.

    1983-06-01

    Documentation for the Safeguards Automated Facility Evaluation (SAFE) computer programs is presented. The documentation is in the form of subprogram trees, program abstracts, flowcharts, and listings. Listings are provided on microfiche

  7. Standards for safe operation of research reactors

    International Nuclear Information System (INIS)

    1996-01-01

    The safety of research reactors is based on many factors such as suitable choice of location, design and construction according to the international standards, it also depends on well trained and qualified operational staff. These standards determine the responsibilities of all who are concerned with the research reactors safe operation, and who are responsible of all related activities in all the administrative and technical stages in a way that insures the safe operation of the reactor

  8. Influencing behaviour for safe working environments

    OpenAIRE

    Boer, de, J. (Johannes); Teeuw, W.B. (Wouter)

    2011-01-01

    Safety at work The objective of the project Safety at Work is to increase safety at the workplace by applying and combining state of the art artefacts from personal protective equipment and ambient intelligence technology. In this state of the art document we focus on the developments with respect to how (persuasive) technology can help to influence behaviour in a natural, automatic way in order to make industrial environments safer. We focus on personal safety, safe environments and safe beh...

  9. Licensing issues for inherently safe fast reactors

    International Nuclear Information System (INIS)

    Kastenberg, W.E.; Lee, S.; Okrent, D.

    1986-01-01

    There has been considerable interest recently in a new generation of liquid metal reactor (LMR) concepts in the US. Some significant changes in regulatory philosophy will be required if the anticipated cost advantages of inherently safe designs are to be achieved. The defense in depth philosophy will need to be significantly re-evaluated in the context of inherently safe reactors. It is the purpose of this paper to begin such a re-evaluation of this regulatory philosophy

  10. Curiosity's Autonomous Surface Safing Behavior Design

    Science.gov (United States)

    Neilson, Tracy A.; Manning, Robert M.

    2013-01-01

    The safing routines on all robotic deep-space vehicles are designed to put the vehicle in a power and thermally safe configuration, enabling communication with the mission operators on Earth. Achieving this goal is made a little more difficult on Curiosity because the power requirements for the core avionics and the telecommunication equipment exceed the capability of the single power source, the Multi-Mission Radioisotope Thermoelectric Generator. This drove the system design to create an operational mode, called "sleep mode", where the vehicle turns off most of the loads in order to charge the two Li-ion batteries. The system must keep the vehicle safe from over-heat and under-heat conditions, battery cell failures, under-voltage conditions, and clock failures, both while the computer is running and while the system is sleeping. The other goal of a safing routine is to communicate. On most spacecraft, this simply involves turning on the receiver and transmitter continuously. For Curiosity, Earth is above the horizon only a part of the day for direct communication to the Earth, and the orbiter overpass opportunities only occur a few times a day. The design must robustly place the Rover in a communicable condition at the correct time. This paper discusses Curiosity's autonomous safing behavior and describes how the vehicle remains power and thermally safe while sleeping, as well as a description of how the Rover communicates with the orbiters and Earth at specific times.

  11. Managing Cassini Safe Mode Attitude at Saturn

    Science.gov (United States)

    Burk, Thomas A.

    2010-01-01

    The Cassini spacecraft was launched on October 15, 1997 and arrived at Saturn on June 30, 2004. It has performed detailed observations and remote sensing of Saturn, its rings, and its satellites since that time. In the event safe mode interrupts normal orbital operations, Cassini has flight software fault protection algorithms to detect, isolate, and recover to a thermally safe and commandable attitude and then wait for further instructions from the ground. But the Saturn environment is complex, and safety hazards change depending on where Cassini is in its orbital trajectory around Saturn. Selecting an appropriate safe mode attitude that insures safe operation in the Saturn environment, including keeping the star tracker field of view clear of bright bodies, while maintaining a quiescent, commandable attitude, is a significant challenge. This paper discusses the Cassini safe table management strategy and the key criteria that must be considered, especially during low altitude flybys of Titan, in deciding what spacecraft attitude should be used in the event of safe mode.

  12. Collection of ministerial circulars on the transport of radioactive substances

    International Nuclear Information System (INIS)

    1977-10-01

    This publication by the CNEN reproduces the full texts of Ministerial Circulars on the transport by road, rail, air and sea of radioactive substances, made in implementation of Act No. 1860 on the peaceful uses of nuclear energy of 1962, as amended by Decree No. 1704 of 1965, laying down that regulatory standards should be elaborated for such transport in accordance with the Euratom basic radiation protection standards and the IAEA Regulations on the Safe Transport of Radioactive Materials. These Circulars are set out in chronological order with reference to the national and international provisions under which they were made. (NEA) [fr

  13. Retrospective Study on the Prevalence and Antibiotic Resistance Pattern of Staphylococcus Aureus and Staphylococcus Epidermidis Among Patients Suspicious of Bacteremia During 2006 - 2011

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Mohaghegh

    2015-05-01

    Full Text Available Background: Staphylococci bacteria cause different diseases, varies from mild skin infections to serious bacteremia. Also they are a major cause of nosocomial and community-acquired infections globally. Staphylococcus aureus and Staphylococcus epidermidis are the two important opportunistic pathogens of the staphylococci that both can cause bacteremia. Objectives: The aim of the present study was to investigate the prevalence and antibiotic resistance pattern of S. aureus and S. epidermidis among blood culture of patients of Ghaem Educational, Research and Treatment Center, Mashhad, Iran, during 6 years (2006 - 2011. Patients and Methods: In this retrospective study, hospital medical records of 28000 patients referred to Ghaem Educational, Research and Treatment Center, Mashhad, Iran, who were suspicious of blood infections during 6 years (2005-2011, were extracted. The patient’s blood culture with staphylococcal growth and their antibiogram results during 2006 - 2011 were collected and studied. Results: Staphylococcus spp. were isolated from 600 (2.14% out of 28000 blood cultures. Furthermore, 420 (70%, 170 (28.3% and 10 (1.7% out of 600 bacterial isolates identified as S. epidermidis, S. aureus and other Staphylococcus spp., respectively. Ampicillin, amoxicillin, cefixime, ceftazidime, penicillin, oxacillin, nalidixic acid and cephepime were the most antibiotics that the isolates were resistant against. Also vancommycin and chloramphenicol were the most effective antibiotics against S. epidermidis and S. aureus, respectively. Conclusions: Prevalence of Staphylococcal bacteremia caused by S. epidermidis is fairly high comparing to S. aureus among patients referred to Ghaem Educational, Research and Treatment Center, Mashhad, Iran. Also the resistance rate of Staphylococcus spp. isolated from blood against commonly used antibiotic is high, but there are some highly sensitive antibiotic against the infection.

  14. Multi-probe-based resonance-frequency electrical impedance spectroscopy for detection of suspicious breast lesions: improving performance using partial ROC optimization

    Science.gov (United States)

    Lederman, Dror; Zheng, Bin; Wang, Xingwei; Wang, Xiao Hui; Gur, David

    2011-03-01

    We have developed a multi-probe resonance-frequency electrical impedance spectroscope (REIS) system to detect breast abnormalities. Based on assessing asymmetry in REIS signals acquired between left and right breasts, we developed several machine learning classifiers to classify younger women (i.e., under 50YO) into two groups of having high and low risk for developing breast cancer. In this study, we investigated a new method to optimize performance based on the area under a selected partial receiver operating characteristic (ROC) curve when optimizing an artificial neural network (ANN), and tested whether it could improve classification performance. From an ongoing prospective study, we selected a dataset of 174 cases for whom we have both REIS signals and diagnostic status verification. The dataset includes 66 "positive" cases recommended for biopsy due to detection of highly suspicious breast lesions and 108 "negative" cases determined by imaging based examinations. A set of REIS-based feature differences, extracted from the two breasts using a mirror-matched approach, was computed and constituted an initial feature pool. Using a leave-one-case-out cross-validation method, we applied a genetic algorithm (GA) to train the ANN with an optimal subset of features. Two optimization criteria were separately used in GA optimization, namely the area under the entire ROC curve (AUC) and the partial area under the ROC curve, up to a predetermined threshold (i.e., 90% specificity). The results showed that although the ANN optimized using the entire AUC yielded higher overall performance (AUC = 0.83 versus 0.76), the ANN optimized using the partial ROC area criterion achieved substantially higher operational performance (i.e., increasing sensitivity level from 28% to 48% at 95% specificity and/ or from 48% to 58% at 90% specificity).

  15. Humic substances in ground waters

    International Nuclear Information System (INIS)

    Paxeus, N.; Allard, B.; Olofsson, U.; Bengtsson, M.

    1986-01-01

    The presence of naturally occurring complexing agents that may enhance the migration of disposed radionuclikes and thus facilitate their uptake by plantsis a problem associated with the underground disposal of radioactive wastes in bedrock. The main purpose of this work is to characterized humic substances from ground water and compare them with humic substances from surface water. The humic materials isolated from ground waters of a borehole in Fjaellveden (Sweden) were characterized by elemental and functional group analyses. Spectroscopic properties, molecular weight distributions as well as acid-base properties of the fulvic and humic fractions were also studied. The ground water humic substances were found to be quite similar in many respects (but not identical) to the Swedish surface water humics concentrated from the Goeta River but appeared to be quite different from the American ground water humics from Biscayne Florida Aquifer or Laramie Fox-Hills in Colorado. The physico-chemical properties of the isolated humic materials are discussed

  16. 76 FR 12719 - Safe Schools/Healthy Students Program; Office of Safe and Drug-Free Schools; Safe Schools/Healthy...

    Science.gov (United States)

    2011-03-08

    ... DEPARTMENT OF EDUCATION Safe Schools/Healthy Students Program; Office of Safe and Drug- Free Schools; Safe Schools/Healthy Students Program; Catalog of Federal Domestic Assistance (CFDA) Numbers: 84... priorities, requirements, and definitions under the Safe Schools/Healthy Students (SS/HS) program. Since...

  17. Process of treating carbonaceous substances

    Energy Technology Data Exchange (ETDEWEB)

    1938-12-16

    A process is described of removing halogens or halogen compounds (or both) from the products which form when carbonaceous substances are treated thermally in the presence of halogens or halogen compounds, consisting of passing the reaction products at the same temperature with a substance able to fix halogens or acid halides through an apparatus included between the receiver and the heat exchanger, which contains, in a relatively restricted space, internal elements obliquely disposed in relation to the direction of the flow, stretched in this direction and constituted preferably of helicoidal passages.

  18. THE CONSEQUENCES OF GLOBALIZATION UPON SAFE TOURISM

    Directory of Open Access Journals (Sweden)

    Svetlana Mihić

    2009-11-01

    Full Text Available Globalization, a phenomenon on the rise, is characterized by the free cross-bor- der movement of individuals, technologies, and capital. It has far- reaching consequen- ces for tourism, too, as it implies travel for leisure and business, and correspondingly, financial transfers between various nation states. Startinf from the status quo in the field, the current paper sets out to analyze the consequences and implications of globalization upon safe tourism and conduct a marketing research into the perceptions of consumers upon Serbia as a safe vacation destination for the purpose of safe tourism. Finally the research results will be presented and several solutions will be provided for improving security in tourism zones

  19. From Safe Systems to Patient Safety

    DEFF Research Database (Denmark)

    Aarts, J.; Nøhr, C.

    2010-01-01

    for the third conference with the theme: The ability to design, implement and evaluate safe, useable and effective systems within complex health care organizations. The theme for this conference was "Designing and Implementing Health IT: from safe systems to patient safety". The contributions have reflected...... and implementation of safe systems and thus contribute to the agenda of patient safety? The contributions demonstrate how the health informatics community has contributed to the performance of significant research and to translating research findings to develop health care delivery and improve patient safety......This volume presents the papers from the fourth International Conference on Information Technology in Health Care: Socio-technical Approaches held in Aalborg, Denmark in June 2010. In 2001 the first conference was held in Rotterdam, The Netherlands with the theme: Sociotechnical' approaches...

  20. Intrinsically Safe and Economical Reactor (ISER)

    International Nuclear Information System (INIS)

    Wakabayashi, Hiroaki; Asahi, Yoshiro

    1991-01-01

    The Intrinsically Safe and Economical Reactor (ISER) is designed based on the principle of a process inherent ultimate safe reactor, PIUS, a so-called inherently safe reactor (ISR). ISER has been developed joingly by the members of the Kanagawa Institute of Technology, the University of Tokyo, the Japan Atomic Energy Research Institute (JAERI) and several industrial firms in Japan. This paper describes the requirements for the next generation of power reactor, the safety design philosphy of ISR and ISER, the controllability of ISER and the results of analyses of some of the design-based accidents (DBA) of ISER, namely station blackout, accidents in which the pressurizer relief valve becomes jammed and stuck in open position and tube breaks in the steam generator. It is concluded that the ISER can ensure a wide range of contraollabitily and fuel integrity for all the analysed DBAs. (orig.)

  1. Inherently safe technologies-chemical and nuclear

    International Nuclear Information System (INIS)

    Weinberg, A.M.

    1984-01-01

    Probabilistic risk assessments show an inverse relationship between the likelihood and the consequences of nuclear and chemical plant accidents, but the Bhopal accident has change public complacency about the safety of chemical plants to such an extent that public confidence is now at the same low level as with nuclear plants. The nuclear industry's response was to strengthen its institutions and improve its technologies, but the public may not be convinced. One solution is to develop reactors which do not depend upon the active intervention of humans of electromechanical devices to deal with emergencies, but which have physical properties that limit the possible temperature and power of a reactor. The Process Inherent Ultimately Safe and the modular High-Temperature Gas-Cooled reactors are two possibilities. the chemical industry needs to develop its own inherently safe design precepts that incorporate smallness, safe processes, and hardening against sabotage. 5 references

  2. Sun Safe Mode Controller Design for LADEE

    Science.gov (United States)

    Fusco, Jesse C.; Swei, Sean S. M.; Nakamura, Robert H.

    2015-01-01

    This paper presents the development of sun safe controllers which are designed to keep the spacecraft power positive and thermally balanced in the event an anomaly is detected. Employed by NASA's Lunar Atmosphere and Dust Environment Explorer (LADEE), the controllers utilize the measured sun vector and the spacecraft body rates for feedback control. To improve the accuracy of sun vector estimation, the least square minimization approach is applied to process the sensor data, which is proven to be effective and accurate. To validate the controllers, the LADEE spacecraft model engaging the sun safe mode was first simulated and then compared with the actual LADEE orbital fight data. The results demonstrated the applicability of the proposed sun safe controllers.

  3. Implications of inherent safe nuclear power system

    International Nuclear Information System (INIS)

    Song, Yo-Taik

    1987-01-01

    The safety of present day nuclear power reactors and research reactors depends on a combination of design features of passive and active systems, and the alert judgement of their operators. A few inherently safe designs of nuclear reactors for power plants are currently under development. In these designs, the passive systems are emphasized, and the active systems are minimized. Also efforts are made to eliminate the potential for human failures that initiate the series of accidents. If a major system fails in these designs, the core is flooded automatically with coolants that flow by gravity, not by mechanical pumps or electromagnetic actuators. Depending on the choice of the coolants--water, liquid metal and helium gas--there are three principal types of inherently safe reactors. In this paper, these inherently safe reactor designs are reviewed and their implications are discussed. Further, future perspectives of their acceptance by nuclear industries are discussed. (author)

  4. The safe transport of radioactive materials

    CERN Document Server

    Gibson, R

    1966-01-01

    The Safe Transport of Radioactive Materials is a handbook that details the safety guidelines in transporting radioactive materials. The title covers the various regulations and policies, along with the safety measures and procedures of radioactive material transport. The text first details the 1963 version of the IAEA regulation for the safe transport of radioactive materials; the regulation covers the classification of radionuclides for transport purposes and the control of external radiation hazards during the transport of radioactive materials. The next chapter deals with concerns in the im

  5. Ergonomics: safe patient handling and mobility.

    Science.gov (United States)

    Hallmark, Beth; Mechan, Patricia; Shores, Lynne

    2015-03-01

    This article reviews and investigates the issues surrounding ergonomics, with a specific focus on safe patient handling and mobility. The health care worker of today faces many challenges, one of which is related to the safety of patients. Safe patient handling and mobility is on the forefront of the movement to improve patient safety. This article reviews the risks associated with patient handling and mobility, and informs the reader of current evidence-based practice relevant to this area of care. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Landscape planning for a safe city

    Directory of Open Access Journals (Sweden)

    M. Ishikawa

    2002-06-01

    Full Text Available To create a safe city free from natural disasters has been one of the important criteria in city planning. Since large cities have suffered from large fires caused by earthquakes, the planning of open spaces to prevent the spread of fires is part of the basic structure of city planning in Japan. Even in the feudal city of Edo, the former name of Tokyo, there had been open spaces to prevent fire disasters along canals and rivers. This paper discusses the historical evolution of open space planning, that we call landscape planning, through the experiences in Tokyo, and clarifies the characteristics and problems for achieving a safe city.

  7. Now, It's Your Turn: How You Can Take Medicine Safely

    Science.gov (United States)

    ... turn Javascript on. Feature: Taking Medicines Safely Now, It's Your Turn: How You Can Take Medicine Safely ... medicine. The pharmacist has filled the prescription. Now it's up to you to take the medicine safely. ...

  8. Substance Abuse and the Family.

    Science.gov (United States)

    Murphy, John P.

    1984-01-01

    Examines the effect that a substance abuser may have on the family system and the maladaptive roles sometimes assumed by family members. Discusses dysfunctional family phases and therapeutic issues and presents 11 guidelines for counselors working with chemically dependent families. (JAC)

  9. Substance Use as Impression Management.

    Science.gov (United States)

    Sharp, Mark J.; Getz, J. Greg

    1996-01-01

    Examines the function of substance use as an impression management tactic. Introductory psychology students (n=377) responded to a survey instrument measuring self-monitoring, perceived success in impression management, interaction anxiety, and self-esteem. Results suggest that alcohol use may serve an impression management function. (JPS)

  10. [Acting out and psychoactive substances: alcohol, drugs, illicit substances].

    Science.gov (United States)

    Gillet, C; Polard, E; Mauduit, N; Allain, H

    2001-01-01

    In humans, some psychotropic agents (alcohol, drugs, illicit substances) have been suggested to play a role in the occurrence of major behavioural disorders, mainly due to the suppression of psychomotor inhibition. Behavioural disinhibition is a physiological mechanism which allows humans to behave appropriately according to a given environmental situation. The behavioural disinhibition induced by either therapeutic dosage or misuse involves the loss of restraint over certain types of social behaviour and may increase the risk of auto or hetero-aggression and acting out. The increased use of psychotropic agents in recent years and the occurrence of unwanted effects are worrying and must be detected and evaluated. The objective of the present study was to establish a causal relationship between psychoactive substance use and occurrence of major behavioural disorders, such as paradoxical rage reactions and suicidal behaviour, based on a literature analysis. It consisted of reviewing reports of drug-induced violent reactions in healthy volunteers and demonstrating, where possible, a cause-effect relationship. Patients with schizophrenia and psychopathic personalities were not included in our study since psychiatric comorbidity could influence behavioural responses. Psychotropic agents included drugs, licit and illicit substances already associated with violence in the past. Many reports used the "Go/No Go test" to evaluate the disinhibiting effect of psychotropic substances; this allows the "cognitive mapping" of drugs. The results suggest that only alcohol, antidepressants, benzodiazepines and cocaïne are related to aggressive behaviour. The best known precipitant of behavioural disinhibition is alcohol, which induces aggressive behaviour. However, there are large differences between individuals, and attentional mechanisms are now recognised as being important in mediating the effects of alcohol. Suicidal tendency as an adverse antidepressant reaction is rare

  11. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas.

    Science.gov (United States)

    Ruckart, Perri Zeitz; Orr, Maureen F; Lanier, Kenneth; Koehler, Allison

    2008-11-15

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

  12. The Formation of Marijuana Risk Perception in a Population of Substance Abusing Patients.

    Science.gov (United States)

    Wilkinson, Samuel T; van Schalkwyk, Gerrit I; Davidson, Larry; D'Souza, Deepak C

    2016-03-01

    Risk perception has been shown to be protective with regard to marijuana use. Notably, the risk perception of marijuana in individuals with substance abuse problems varies significantly from that of the general public. Understanding how risk perception is formed in substance users could explain these differences and help predict the consequences of policy changes. Using this framework, we explored risk perception and its formation in a sample of substance abusing veterans. Semi-structured interviews were conducted with veterans who were receiving treatment for substance abuse. Interviews were recorded digitally, transcribed verbatim, and analyzed using inductive thematic analysis. A prominent perspective among the 31 participants was that marijuana is significantly different from other drugs because it is safe, not addictive, not associated with physical withdrawal, and has less overt behavioral effects than other substances. Many of these participants drew upon their own innocuous experiences with the drug in developing this perspective, more so than information from any other source. A contrasting narrative emphasized marijuana's capacity to cause negative social consequences, act as a gateway to the use of other, more harmful substances, and cause paranoia or worsen psychosis. In conclusion, individual experience with marijuana featured more prominently in informing risk perception than any other source of information. Our results and previous literature suggest that the significant disconnect between the individual experiences of substance users and the current clinical and legal policy towards marijuana may weaken the legitimacy of public policy or the authority of the medical community.

  13. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

    International Nuclear Information System (INIS)

    Ruckart, Perri Zeitz; Orr, Maureen F.; Lanier, Kenneth; Koehler, Allison

    2008-01-01

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews

  14. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

    Energy Technology Data Exchange (ETDEWEB)

    Ruckart, Perri Zeitz [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)], E-mail: afp4@cdc.gov; Orr, Maureen F. [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States); Lanier, Kenneth; Koehler, Allison [Louisiana Department of Health and Hospitals, Office of Public Health, New Orleans, LA (United States)

    2008-11-15

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

  15. How safe are nuclear power plants

    International Nuclear Information System (INIS)

    Danzmann, H.J.

    1976-01-01

    The question 'how safe are nuclear power plants' can be answered differently - it depends on how the term 'safety' is understood. If the 'safety of supply' is left out as a possibility of interpretation, then the alternative views remain: Operational safety in the sense of reliability and safety of personnel and population. (orig.) [de

  16. Safe and Healthy Travel to China

    Centers for Disease Control (CDC) Podcasts

    2008-10-09

    In this podcast, Dr. Phyllis Kozarsky, CDC Travel Medicine expert, discusses what travelers should do to ensure a safe and healthy trip to China.  Created: 10/9/2008 by National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID), Division of Global Migration and Quarantine (DGMQ).   Date Released: 10/9/2008.

  17. Safe Space Oddity: Revisiting Critical Pedagogy

    Science.gov (United States)

    Redmond, Melissa

    2010-01-01

    Inspired by an incident in a social work graduate classroom in which she was a teaching assistant, the author reflects on her commitment to constructivist teaching methods, critical theory, and critical pedagogy. Exploring the educational utility of notions such as public space and safe space, the author employs this personal experience to examine…

  18. Safe reduction rules for weighted treewidth

    NARCIS (Netherlands)

    Eijkhof, F. van den; Bodlaender, H.L.; Koster, A.M.C.A.

    2002-01-01

    Several sets of reductions rules are known for preprocessing a graph when computing its treewidth. In this paper, we give reduction rules for a weighted variant of treewidth, motivated by the analysis of algorithms for probabilistic networks. We present two general reduction rules that are safe for

  19. Safe laparoscopic colorectal surgery performed by trainees

    DEFF Research Database (Denmark)

    Langhoff, Peter Koch; Schultz, Martin; Harvald, Thomas

    2013-01-01

    Laparoscopic surgery for colorectal cancer is safe, but there have been hesitations to implement the technique in all departments. One of the reasons for this may be suboptimal learning possibilities since supervised trainees have not been allowed to do the operations to an adequate extent...

  20. Safe and secure: transportation of radioactive materials

    International Nuclear Information System (INIS)

    Howe, D.

    2015-01-01

    Western Waste Management Facility is Central Transportation Facility for Low and Intermediate waste materials. Transportation support for Stations: Reactor inspection tools and heavy water between stations and reactor components and single bundles of irradiated fuel to AECL-Chalk River for examination. Safety Track Record: 3.2 million kilometres safely travelled and no transportation accident - resulting in a radioactive release.

  1. Using over-the-counter medicines safely

    Science.gov (United States)

    ... about OTC drugs. About OTC Medicines You can buy OTC medicines without a prescription in: Drug stores Grocery stores ... Safely You should: Examine the package before you buy it. Make sure it has not been tampered with. Never use medicine you have bought that does not look the ...

  2. Safe Sleep for Babies PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    This 60 second public service announcement is based on the January 2018 CDC Vital Signs report. Every year, there are about 3,500 sleep-related deaths among U.S. babies. Learn how to create a safe sleep environment for babies.

  3. Stay Safe and Healthy This Winter!

    Centers for Disease Control (CDC) Podcasts

    2010-11-23

    In this podcast for kids, the Kidtastics offer some simple ways to stay safe and healthy during the winter holiday season.  Created: 11/23/2010 by CDC Office of Women’s Health.   Date Released: 11/23/2010.

  4. Safe injection procedures, injection practices, and needlestick ...

    African Journals Online (AJOL)

    Nermine Mohamed Tawfik Foda

    2017-01-10

    Jan 10, 2017 ... Background: Of the estimated 384,000 needle-stick injuries occurring in hospitals each year, 23% occur in surgical settings. This study was conducted to assess safe injection procedures, injection practices, and circumstances contributing to needlestick and sharps injures (NSSIs) in operating rooms.

  5. Disabled Children: The Right to Feel Safe

    Science.gov (United States)

    Mepham, Sarah

    2010-01-01

    This article explores the fundamental right of disabled children to feel safe and be free from bullying, harassment and abuse. The article proposes that, 20 years since the United Nations Convention on the Rights of the Child, disabled children are still facing barriers to securing this right. The article focuses on recent Mencap research that…

  6. School Counselors: Untapped Resources for Safe Schools.

    Science.gov (United States)

    Callahan, Connie J.

    2000-01-01

    Principals should consider redirecting school counselors' responsibilities to include directing safe-school teams; establishing networks to identify at-risk students and violent behavior signs; developing conflict-resolution activities; assessing and counseling misbehaving students; devising crisis- management plans; and helping staff predict and…

  7. How to Keep Your Sleeping Baby Safe

    Science.gov (United States)

    ... first hour. After that, or when the mother needs to sleep or cannot do skin-to-skin, babies should ... Back is Best New Crib Standards: What Parents Need to Know Safe Sleep for Babies (Video) The Healthy Children Show: Sleep ( ...

  8. Education in Safe and Unsafe Spaces

    Science.gov (United States)

    Callan, Eamonn

    2016-01-01

    Recent student demands within the academy for "safe space" have aroused concern about the constraints they might impose on free speech and academic freedom. There are as many kinds of safety as there are threats to the things that human beings might care about. That is why we need to be very clear about the specific threats of which the…

  9. Asymptotically Safe Standard Model via Vectorlike Fermions

    Science.gov (United States)

    Mann, R. B.; Meffe, J. R.; Sannino, F.; Steele, T. G.; Wang, Z. W.; Zhang, C.

    2017-12-01

    We construct asymptotically safe extensions of the standard model by adding gauged vectorlike fermions. Using large number-of-flavor techniques we argue that all gauge couplings, including the hypercharge and, under certain conditions, the Higgs coupling, can achieve an interacting ultraviolet fixed point.

  10. Have a Safe and Healthy Fall

    Centers for Disease Control (CDC) Podcasts

    2010-10-14

    Fall is a great time to try new and healthy activities with your parents! Have a food tasting or a leaf raking contest! Whatever your plans, make sure to have fun and be safe!  Created: 10/14/2010 by CDC Office of Women’s Health.   Date Released: 10/14/2010.

  11. Safe Handling of Radioisotopes. First Edition with Revised Appendix I

    International Nuclear Information System (INIS)

    1966-01-01

    Under its Statute the International Atomic Energy Agency is empowered to provide for the application of standards of safety for protection against radiation to its own operations and to operations making use of assistance provided by it or with which it is otherwise directly associated. To this end authorities receiving such assistance are required to observe relevant health and safety measures prescribed by the Agency. As a first step, it was considered an urgent task to provide users of radioisotopes with a manual of practice for the safe handling of these substances. The first edition of such a manual was published in 1958 and represented the first of the 'Safety Series', a series of manuals and codes on health and safety published by the Agency. It was prepared after careful consideration of existing national and international codes of radiation safety by a group of international experts and in consultation with other international bodies. This edition presents the first revision. It incorporates in the Appendices the latest recommendations of the International Commission on Radiological Protection and extracts from the report of the Committee II of the I.C.R.P. on permissible dose for internal radiation. The Health Physics and Medical Addenda to this Manual, published as No. 2 and No. 3 in the Safety Series in 1960, give more complete advice to the user on specialized topics.

  12. Elaboration of Safe Community Assessment System

    Directory of Open Access Journals (Sweden)

    Birutė Mikulskienė

    2013-08-01

    Full Text Available The paper aims to design an assessment system to monitor and evaluate safety parameters and administrative efforts with the purpose to increase safety in municipalities. The safety monitoring system considered is to be the most important tool for creation and development of safe communities in Lithuania. Several methods were applied to achieve this purpose. In order to determine the role of local government in ensuring the safety of people, property and environment at the local level of a meta-analysis of research reports, the Lithuanian national legislation, strategic planning documents of the state and local government were carried out. Analysis of statistical data, structural analysis, comparative analysis and synthesis methods were used while investigating the areas of safety uncertainty, risk groups, identifying safety risk factors, determining their relationship, and creating a safe community assessment system. A safe community assessment system, which consists of two types of criteria, has been elaborated. The assessment system is based on the multi-level criteria for safety monitoring and the multi-level criteria for the evaluation of municipal activities in the field of building safety. Links between the criteria, peculiarities of their application and advantages in the process of safe community creation and development are analyzed. Design and implementation of the safe community assessment system is one of the most important stages to implement the idea of safe communities. The proposed system integrates a variety of risk areas, the safety achievement criteria are linked to the criteria used in the strategic planning. Periodic assessment of the safety situation using the proposed system ensures possibility to monitor current local safety conditions and assess the changes and the trends. A safe community assessment system is proposed to be used as a tool to unified municipalities safety comprehensiveness and compare safety level in

  13. Elaboration of Safe Community Assessment System

    Directory of Open Access Journals (Sweden)

    Algirdas Astrauskas

    2011-12-01

    Full Text Available The paper aims to design an assessment system to monitor and evaluate safety parameters and administrative efforts with the purpose to increase safety in municipalities. The safety monitoring system considered is to be the most important tool for creation anddevelopment of safe communities in Lithuania. Several methods were applied to achieve this purpose. In order to determine the role of local government in ensuring the safety of people, property and environment at the local level of a meta-analysis of research reports,the Lithuanian national legislation, strategic planning documents of the state and local government were carried out. Analysis of statistical data, structural analysis, comparative analysis and synthesis methods were used while investigating the areas of safety uncertainty, risk groups, identifying safety risk factors, determining their relationship, and creating a safe community assessment system.A safe community assessment system, which consists of two types of criteria, has been elaborated. The assessment system is based on the multi-level criteria for safety monitoring and the multi-level criteria for the evaluation of municipal activities in the field of building safety. Links between the criteria, peculiarities of their application and advantages in the process of safe community creation and development are analyzed.Design and implementation of the safe community assessment system is one of the most important stages to implement the idea of safe communities. The proposed system integrates a variety of risk areas, the safety achievement criteria are linked to the criteria used in thestrategic planning. Periodic assessment of the safety situation using the proposed system ensures possibility to monitor current local safety conditions and assess the changes and the trends. A safe community assessment system is proposed to be used as a tool to unified municipalities safety comprehensiveness and compare safety level in

  14. The pros and cons of safe electronuclear station with accelerator as a driver

    International Nuclear Information System (INIS)

    Svistunov, Yu.A.; Vorogushin, M.F.; Gavrish, Yu.N.; Kudinovich, I.V.; Struev, V.P.

    2001-01-01

    Creation of 200 MW compact safe energetic installation on a base of a high-temperature, gas-cooled,subcritical reactor was discussed in paper. Chain reaction was initiated by the outer neutron flow. It was proposed to obtain such a source by irradiation of different substances with an intensive proton beam from the linac. Now possibilities of such a scheme are considered in more details.Structure of the reactor active zone is discussed. The use of the cyclotron as a driver is considered as an alternative variant. Problems of reliability, radiation safety and cost of installation are taken into account too

  15. The pros and cons of safe electronuclear station with accelerator as a driver

    CERN Document Server

    Svistunov, Y A; Gavrish, Y N; Kudinovich, I V; Struev, V P

    2001-01-01

    Creation of 200 MW compact safe energetic installation on a base of a high-temperature, gas-cooled,subcritical reactor was discussed in paper. Chain reaction was initiated by the outer neutron flow. It was proposed to obtain such a source by irradiation of different substances with an intensive proton beam from the linac. Now possibilities of such a scheme are considered in more details.Structure of the reactor active zone is discussed. The use of the cyclotron as a driver is considered as an alternative variant. Problems of reliability, radiation safety and cost of installation are taken into account too.

  16. ORIGINAL ARTICLES An epidemiological perspective of substance ...

    African Journals Online (AJOL)

    2002-09-06

    Sep 6, 2002 ... advertising linking alcohol with the glamour of sport. This inculcates values that ... of substance use is a useful preventive strategy, hence the importance of ... substance use and associated factors (including age, gender,.

  17. Dual Diagnosis: Substance Abuse and Mental Illness

    Science.gov (United States)

    ... is a term for when someone experiences a mental illness and a substance use disorder simultaneously. Either disorder—substance use or mental illness—can develop first. People experiencing a mental health ...

  18. EPA Linked Open Data: Substance Registry Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — Substance Registry Services (SRS) is the Environmental Protection Agency's (EPA) central system for information about substances that are tracked or regulated by EPA...

  19. Agency for Toxic Substances and Disease Registry

    Science.gov (United States)

    ... Z # Search Form Controls Search The CDC submit Agency for Toxic Substances and Disease Registry Note: Javascript ... gov . Recommend on Facebook Tweet Share Compartir The Agency for Toxic Substances and Disease Registry (ATSDR) , based ...

  20. Abortion Legalization and Adolescent Substance Use

    OpenAIRE

    Charles, Kerwin Kofi; Stephens, Melvin, Jr

    2006-01-01

    We assess whether in utero exposure to legalized abortion in the early 1970's affected individuals' propensities to use controlled substances as adolescents. We exploit the fact that some states legalized abortion before national legalization in 1973 to compare differences in substance use for adolescents across birth cohorts in different states. We find that persons exposed to early legalization were, on average, much less likely to use controlled substances. We also assess how substance use...

  1. Substance Abuse in Aging Population

    Directory of Open Access Journals (Sweden)

    Alireza Jazayeri

    2006-10-01

    Full Text Available substance abuse' specially opiates and prescribed drugs are spreading among the older adults. Most of the time it begins as an attempt to medicate chronic pains, medical conditions and loneliness. In other instances, it simply is the continuation of a problem that begun in young adulthood. But scholars and specialists in both fields of Addiction and Gerontology, rather neglected this fast growing problem, to the extent that we almost have no data on the epidemiology, prevention and treatment modalities among the substance abusing old adults in Iran. This paper reflects the necessity of designing age specific programs to identify and treat this group. Besides, some of the most effictive methods of treatment in other countries are reviewed.

  2. Psychotropic substances in indoor environments.

    Science.gov (United States)

    Cecinato, Angelo; Romagnoli, Paola; Perilli, Mattia; Patriarca, Claudia; Balducci, Catia

    2014-10-01

    The presence of drugs in outdoor air has been established, but few investigations have been conducted indoors. This study focused on psychotropic substances (PSs) at three schools, four homes and one office in Rome, Italy. The indoor drug concentrations and the relationships with the outdoor atmosphere were investigated. The optimised monitoring procedure allowed for the determination of cocaine, cannabinoids and particulate fractions of nicotine and caffeine. In-field experiments were performed during the winter, spring and summer seasons. Psychotropic substances were observed in all indoor locations. The indoor concentrations often exceeded those recorded both outdoors at the same sites and at the atmospheric pollution control network stations, indicating that the drugs were released into the air at the inside sites or were more persistent. During winter, the relative concentrations of cannabinol, cannabidiol and tetrahydrocannabinol depended on site and indoor/outdoor location at the site. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Safeguards Automated Facility Evaluation (SAFE) methodology

    International Nuclear Information System (INIS)

    Chapman, L.D.; Grady, L.M.; Bennett, H.A.; Sasser, D.W.; Engi, D.

    1978-08-01

    An automated approach to facility safeguards effectiveness evaluation has been developed. This automated process, called Safeguards Automated Facility Evaluation (SAFE), consists of a collection of a continuous stream of operational modules for facility characterization, the selection of critical paths, and the evaluation of safeguards effectiveness along these paths. The technique has been implemented on an interactive computer time-sharing system and makes use of computer graphics for the processing and presentation of information. Using this technique, a comprehensive evaluation of a safeguards system can be provided by systematically varying the parameters that characterize the physical protection components of a facility to reflect the perceived adversary attributes and strategy, environmental conditions, and site operational conditions. The SAFE procedure has broad applications in the nuclear facility safeguards field as well as in the security field in general. Any fixed facility containing valuable materials or components to be protected from theft or sabotage could be analyzed using this same automated evaluation technique

  4. Method of safely operating nuclear reactor

    International Nuclear Information System (INIS)

    Ochiai, Kanehiro.

    1976-01-01

    Purpose: To provide a method of safely operating an nuclear reactor, comprising supporting a load applied to a reactor container partly with secondary container facilities thereby reducing the load borne by the reactor container when water is injected into the core to submerge the core in an emergency. Method: In a reactor emergency, water is injected into the reactor core thereby to submerge the core. Further, water is injected into a gap between the reactor container and the secondary container facilities. By the injection of water into the gap between the reactor container and the secondary container facilities a large apparent mass is applied to the reactor container, as a result of which the reactor container undergoes the same vibration as that of the secondary container facilities. Therefore, the load borne by the reactor container itself is reduced and stress at the bottom part of the reactor container is released. This permits the reactor to be operated more safely. (Moriyama, K.)

  5. Safe waste management practices in beryllium facilities

    International Nuclear Information System (INIS)

    Bhat, P.N.; Soundararajan, S.; Sharma, D.N.

    2012-01-01

    Beryllium, an element with the atomic symbol Be, atomic number 4, has very high stiffness to weight ratio and low density. It has good electrical conductive properties with low coefficient of thermal expansion. These properties make the metal beryllium very useful in varied technological endeavours, However, beryllium is recognised as one of the most toxic metals. Revelation of toxic effects of beryllium resulted in institution of stringent health and safety practices in beryllium handling facilities. The waste generated in such facilities may contain traces of beryllium. Any such waste should be treated as toxic waste and suitable safe waste management practices should be adopted. By instituting appropriate waste management practice and through a meticulously incorporated safety measures and continuous surveillance exercised in such facilities, total safety can be ensured. This paper broadly discusses health hazards posed by beryllium and safe methods of management of beryllium bearing wastes. (author)

  6. TOXICOLOGICAL ENDPOINTS OF DOPING SUBSTANCES

    OpenAIRE

    BASARAN, A. Ahmet

    2018-01-01

    Athletes and non athletes weighlifters have tried to gain an unfairadvantage through the use doping substances since ancient times. Dopingsubstances although enhance sports performance, represent a risk to the healthof individuals and violate the sprit of competition. The use of prohibitedperformance enhancing drugs (PED’s) or methods to improve results incompetitive sports is referred as doping. Among the PED’s used areandrogenic-anabolic steroids (AASs), diuretics and masking agents, narkot...

  7. The administration of radioactive substances

    International Nuclear Information System (INIS)

    Bourdillon, P.J.; Godfrey, B.E.; O'Brien, R.

    1983-01-01

    A brief history is given of the evolution of a system to approve the licensing of doctors and dentists to use radioactive medicinal products in man. Currently, the Administration of Radioactive Substances Advisory Committee (ARSAC) is appointed by UK Health Ministers to advise them on the granting, renewal, suspension, revocation and variation of certificates. The type of information requested on the application form for a certificate is outlined. (UK)

  8. Advising Your Elderly Patients Concerning Safe Exercising

    OpenAIRE

    Myers, Anita

    1987-01-01

    With the emergence of physical activity programs geared specifically to senior citizens, family physicians will increasingly be called on to provide advice or approval concerning their patients' suitability for participation. In addition, family physicians have been identified as having a key role to play in the promotion of exercise for sedentary older adults. To assist the family practitioner in advising elderly patients concerning safe exercise patterns, this article discusses the document...

  9. The Safe Transportation of Radioactive Materials

    International Nuclear Information System (INIS)

    Megrahi, Abdulhafeed; Abu-Ali, Giuma; Enhaba; Ahmed

    2008-01-01

    In this paper, we present the essential conditions that should be required for transporting the radioactive materials. We demonstrate the procedure for transporting the radioactive iodine-131 from the Centre of Renewable Energies and Desalination of Water in Tajoura, Libya to Tripoli Medical Center. The safe measures were taken during the process of the transportation of the isotope produced in the centre including dosimetry analysis and the thickness of the container. (author)

  10. Safe handling of plutonium in research laboratories

    International Nuclear Information System (INIS)

    1976-01-01

    The training film illustrates the main basic requirements for the safe handling of small amounts of plutonium. The film is intended not only for people setting up plutonium research laboratories but also for all those who work in existing plutonium research laboratories. It was awarded the first prize in the category ''Protection of Workers'' at the international film festival organized by the 4th World Congress of the International Radiation Protection Association (IRPA) in Paris in April 1977

  11. Procedure of safe handling with cytostatic drugs

    Directory of Open Access Journals (Sweden)

    Kodžo Dragan

    2003-01-01

    Full Text Available Working group for safe handling with cytostatic drugs has been formed by the Ministry of Health, and it consists of professionals from IORS, Federal Bureau of Weights and Measures, Industrial Medicine, Institute of Hematology, Military Medical Academy, and Crown Agents. The aim of this working group is to prepare procedures for safe handling with cytostatic drugs, as well as program for educational seminar for nurses, medical technicians, and pharmaceutical technicians. The procedures will serve as a guide of good practice of oncology health care, and will refer to all actions that health care professionals carry out from the moment of drugs arrival to the pharmacy to the moment of their application. In the first segment of this procedure, general rules are given for working with cytotoxic agents, control for risky exposures, safe system of work, control of working environment, monitoring of the employees' health condition adequate protection in the working environment, protective equipment of the employees (gloves, mask, cap, eyeglasses, shoe covers, coats and chambers for vertical laminary air stream. Storing of cytostatics, procedure in case of accident, and waste handling and removal are also described in this segment. Fifty-three standard operational procedures are described in detail in the second segment. Training scheme for preparation of chemotherapy is given in the third segment - education related to various fields and practical part, which would be carried out through workshops, and at the end of the course participants would pass a test and obtain certificate. After the procedures for safe handling with cytostatics are legally regulated employer will have to provide minimum of protective equipment, special rooms for the drugs dissolving, chambers with laminar airflow, 6 hours working time, rotation of the staff working with drugs dissolving in intervals of every five years, higher efficiency, better health control. In conclusion

  12. Safe Sleep for Babies PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2018-01-09

    This 60 second public service announcement is based on the January 2018 CDC Vital Signs report. Every year, there are about 3,500 sleep-related deaths among U.S. babies. Learn how to create a safe sleep environment for babies.  Created: 1/9/2018 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/9/2018.

  13. Esomeprazole: a safe alternative to lansoprazole allergy?

    Science.gov (United States)

    Kara, Muammer; Tanoglu, Alpaslan; Kutlu, Ali; Sirkeci, Ozgur; Kekilli, Murat

    2014-08-01

    Proton pump inhibitors (PPIs) are widely prescribed drugs in daily practice. Allergic reactions, even small number of anaphylactic reactions to PPIs have been reported. Omeprazole, lansoprazole, pantoprazole, rapeprazol and esomeprazole are classified in the same group. Despite the similarity of biochemical structures among these drugs, presence of cross-reactivity between PPIs is controversial.1,2 In this letter, we present 3 lansoprazole allergy cases, who were prescribed and took esomeprazole safely after allergic reactions to lansoprazole.

  14. Human cloning: can it be made safe?

    Science.gov (United States)

    Rhind, Susan M; Taylor, Jane E; De Sousa, Paul A; King, Tim J; McGarry, Michelle; Wilmut, Ian

    2003-11-01

    There are continued claims of attempts to clone humans using nuclear transfer, despite the serious problems that have been encountered in cloning other mammals. It is known that epigenetic and genetic mechanisms are involved in clone failure, but we still do not know exactly how. Human reproductive cloning is unethical, but the production of cells from cloned embryos could offer many potential benefits. So, can human cloning be made safe?

  15. Iser: an international inherently safe reactor concept

    International Nuclear Information System (INIS)

    Wakabayashi, Hiroaki

    1988-01-01

    Iser is a modular standardised 200-300 MWe power reactor based on the PIUS principle. It differs from PIUS in being simpler, and making full use of existing steel-vessel-based LWR technology. Iser is an inherently safe reactor concept under development in Japan. It is a generic concept, not a patented commodity, and it is expected that an international association to develop the concept will be formed. (U.K.)

  16. SIR - small is safe [in reactor design

    International Nuclear Information System (INIS)

    Hayns, M.

    1989-01-01

    A joint USA-UK venture has been initiated to design a small nuclear reactor which offers low capital cost, greater flexibility and a potentially lower environmental impact. Called Safe Integral Reactor (SIR), the lead unit could be built in the United Kingdom Atomic Energy Authority's (UKAEA's) Winfrith site if the design is accepted by the UK Nuclear Installations Inspectorate (NII). This article describes the 320 MWe reactor unit that is the basis of the design being developed. (author)

  17. Safe handling of plutonium in research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1977-12-31

    The training film illustrates the main basic requirements for the safe handling of small amounts of plutonium. The film is intended not only for people setting up plutonium research laboratories but also for all those who work in existing plutonium research laboratories. It was awarded the first prize in the category ``Protection of Workers`` at the international film festival organized by the 4th World Congress of the International Radiation Protection Association (IRPA) in Paris in April 1977

  18. Managing radioactive waste safely. Engaging Scotland

    International Nuclear Information System (INIS)

    Elrick, D.; Boyes, L.; McCormick, J.

    2002-01-01

    Between January and May 2002 the Scottish Council Foundation undertook a research project to assess 1 the level of public awareness about and interest in engaging the public in decision-making on managing radioactive waste safely in Scotland. This paper presents the main findings from the research that involved 70 people from across Scotland, aged between 14 and over 65 years old, and a literature review of Scottish, UK and international experience in engaging the public

  19. Substance misuse in Aboriginal Australians.

    Science.gov (United States)

    Gracey, M

    1998-01-01

    Australia's Aborigines lived in isolation from the rest of humanity as successful hunter-gatherers for tens of thousands of years. That isolation ended abruptly with British colonization in the late 18th century and was followed by a traumatic 200 years for Aborigines who are now seriously disadvantaged, socio-economically and in terms of their health standards. It has often been assumed that the Aborigines had no access to psychotropic substances before permanent European contact but several pieces of evidence dispute this view. The history of Aboriginal contact with and usage of intoxicating substances, including alcohol, is extremely complex and affected by a maze of restrictive government policies. These interact with a wide range of other Federal and State policies which have changed rapidly since the late 1960s when Aborigines were first granted the franchise; access to unrestricted drinking followed soon afterwards. Today Aborigines suffer disproportionately to other Australians from the physical and social consequences of excess alcohol consumption, tobacco usage, petrol and other solvent sniffing, usage of marijuana, amphetamines, cocaine and heroin, as well as other drugs. The Aboriginal population is dispersed in cities, towns, fringe settlements, rural and remote areas over this vast continent and there are different patterns of drug usage from place to place. This review attempts to synthesize some of this information in order to give an overview to the history, background, current status of substance misuse by Aborigines as well as some strategies being used to try to overcome this serious problem.

  20. Dermal uptake of petroleum substances.

    Science.gov (United States)

    Jakasa, Ivone; Kezic, Sanja; Boogaard, Peter J

    2015-06-01

    Petroleum products are complex substances comprising varying amounts of linear and branched alkanes, alkenes, cycloalkanes, and aromatics which may penetrate the skin at different rates. For proper interpretation of toxic hazard data, understanding their percutaneous absorption is of paramount importance. The extent and significance of dermal absorption of eight petroleum substances, representing different classes of hydrocarbons, was evaluated. Literature data on the steady-state flux and permeability coefficient of these substances were evaluated and compared to those predicted by mathematical models. Reported results spanned over 5-6 orders of magnitude and were largely dependent on experimental conditions in particular on the type of the vehicle used. In general, aromatic hydrocarbons showed higher dermal absorption than more lipophilic aliphatics with similar molecular weight. The results showed high variation and were largely influenced by experimental conditions emphasizing the need of performing the experiments under "in use" scenario. The predictive models overestimated experimental absorption. The overall conclusion is that, based on the observed percutaneous penetration data, dermal exposure to petroleum hydrocarbons, even of aromatics with highest dermal absorption is limited and highly unlikely to be associated with health risks under real use scenarios. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  1. Safe Cooperating Cyber-Physical Systems using Wireless Communication

    DEFF Research Database (Denmark)

    Pop, Paul; Scholle, Detlef; Sljivo, Irfan

    2017-01-01

    This paper presents an overview of the ECSEL project entitled ―Safe Cooperating Cyber-Physical Systems using Wireless Communication‖ (SafeCOP), which runs during the period 2016–2019. SafeCOP targets safety-related Cooperating Cyber-Physical Systems (CO-CPS) characterised by use of wireless...... detection of abnormal behaviour, triggering if needed a safe degraded mode. SafeCOP will also develop methods and tools, which will be used to produce safety assurance evidence needed to certify cooperative functions. SafeCOP will extend current wireless technologies to ensure safe and secure cooperation...

  2. Safe transport of radioactive material. Second edition

    International Nuclear Information System (INIS)

    1991-01-01

    The transport of radioactive material embraces the carriage of radioisotopes for industrial, medical and research uses, and the movement of waste, in addition to consignments of nuclear fuel cycle material. It has been estimated that between eighteen and thirty-eight million package shipments take place each year. On the recommendation of the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM), which enjoys wide representations from the Agency's Member States and international organizations, the Secretariat is preparing a training kit comprising this training manual and complementary visual aids. The kit is intended to be the basis for an extensive course on the subject and can be used in whole or in part for inter-regional, regional and even national training purposes. Member States can thus benefit from the material either through training courses sponsored by the Agency, or, alternatively, organized by themselves. As a step towards achieving that goal, the current training manual was compiled using material from the first Inter-Regional Training Course on the Safe Transport of Radioactive material that was held in co-operation with the Nuclear Power Training Centre of the then Central Electricity Generating Board at Bristol, United Kingdom. This Manual was initially published in 1990. On the recommendation of the Agency's Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM), the Manual has since been expanded and updated in time for the second Inter-Regional Training Course, that will in 1991 similarly be held in Bristol. Refs, figs, tabs

  3. Safe transport of radioactive materials in Egypt

    International Nuclear Information System (INIS)

    El-Shinawy, R.M.K.

    1994-01-01

    In Egypt the national regulations for safe transport of radioactive materials (RAM) are based on the International Atomic Energy Agency (IAEA) regulations. In addition, regulations for the safe transport of these materials through the Suez Canal (SC) were laid down by the Egyptian Atomic Energy Authority (EAEA) and the Suez Canal Authority (SCA). They are continuously updated to meet the increased knowledge and the gained experience. The technical and protective measures taken during transport of RAM through SC are mentioned. Assessment of the impact of transporting radioactive materials through the Suez Canal using the INTERTRAN computer code was carried out in cooperation with IAEA. The transported activities and empty containers, the number of vessels carrying RAM through the canal from 1963 and 1991 and their nationalities are also discussed. The protective measures are mentioned. A review of the present situation of the radioactive wastes storage facilities at the Atomic Energy site at Inshas is given along with the regulation for safe transportation and disposal of radioactive wastes. (Author)

  4. Inherently safe in situ uranium recovery

    International Nuclear Information System (INIS)

    Krumhansl, James Lee; Beauheim, Richard Louis; Brady, Patrick Vane; Arnold, Bill Walter; Kanney, Joseph F.; McKenna, Sean Andrew

    2009-01-01

    Expansion of uranium mining in the United States is a concern to some environmental groups and sovereign Native American Nations. An approach which may alleviate some problems is to develop inherently safe in situ uranium recovery ('ISR') technologies. Current ISR technology relies on chemical extraction of trace levels of uranium from aquifers that, once mined, can still contain dissolved uranium and other trace metals that are a health concern. Existing ISR operations are few in number; however, high uranium prices are driving the industry to consider expanding operations nation-wide. Environmental concerns and enforcement of the new 30 ppb uranium drinking water standard may make opening new mining operations more difficult and costly. Here we propose a technological fix: the development of inherently safe in situ recovery (ISISR) methods. The four central features of an ISISR approach are: (1) New 'green' leachants that break down predictably in the subsurface, leaving uranium, and associated trace metals, in an immobile form; (2) Post-leachant uranium/metals-immobilizing washes that provide a backup decontamination process; (3) An optimized well-field design that increases uranium recovery efficiency and minimizes excursions of contaminated water; and (4) A combined hydrologic/geochemical protocol for designing low-cost post-extraction long-term monitoring. ISISR would bring larger amounts of uranium to the surface, leave fewer toxic metals in the aquifer, and cost less to monitor safely - thus providing a 'win-win-win' solution to all stakeholders.

  5. Substance misuse and substance use disorders in sex offenders: a review

    NARCIS (Netherlands)

    Kraanen, F.L.; Emmelkamp, P.M.G.

    2011-01-01

    Substance abuse has often been associated with committing sex offenses. In this article, the following will be reviewed: 1) studies that assessed substance abuse in sex offenders; 2) differences in substance abuse among different types of sex offenders; 3) differences in substance abuse between sex

  6. 21 CFR 172.510 - Natural flavoring substances and natural substances used in conjunction with flavors.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Natural flavoring substances and natural substances used in conjunction with flavors. 172.510 Section 172.510 Food and Drugs FOOD AND DRUG ADMINISTRATION....510 Natural flavoring substances and natural substances used in conjunction with flavors. Natural...

  7. 21 CFR 182.70 - Substances migrating from cotton and cotton fabrics used in dry food packaging.

    Science.gov (United States)

    2010-04-01

    ... used in dry food packaging. 182.70 Section 182.70 Food and Drugs FOOD AND DRUG ADMINISTRATION... used in dry food packaging. Substances migrating to food from cotton and cotton fabrics used in dry food packaging that are generally recognized as safe for their intended use, within the meaning of...

  8. Autoradiographic localization of substance P receptors using 125I substance P

    International Nuclear Information System (INIS)

    Shults, C.W.; Quirion, R.; Jensen, R.T.; Moody, T.W.; O'Donohue, T.L.; Chase, T.N.

    1982-01-01

    This paper describes a method for localization of substance P receptors in the rat central nervous system using 125 I labeled substance P in an autoradiographic procedure. Particularly high densities of substance P receptors were observed in the olfactory bulb, dentate gyrus, amygdala, superior colliculus, and locus coeruleus. Surprisingly low densities of substance P receptors were found in the substantia nigra pars reticulata, a region which contains high concentrations of substance P

  9. Psychographic Segments of College Females and Males in Relation to Substance Use Behaviors.

    Science.gov (United States)

    Suragh, Tiffany Ashley; Berg, Carla J; Nehl, Eric J

    2013-09-01

    A common commercial marketing segmentation technique is to divide a population into groups based on psychographic characteristics (i.e., attitudes and interests). We used this approach to define segments of female and male college students and examine substance use differences. We administered an online survey to 24,055 students at six colleges in the Southeastern United States (response rate 20.1%, n = 4,840), obtaining complete data from 3,469 participants. We assessed sociodemographics, psychographic factors such as those used by the tobacco industry to define market segments, and substance use (cigarettes, other tobacco products, alcohol, and marijuana). Cluster analysis was conducted among females and males using 15 psychographic measures (sensation seeking, Big Five personality traits, and nine measures adapted from tobacco industry documents), identifying three segments per sex. Safe responsibles were characterized by high levels of agreeableness, conscientiousness, emotional stability, academic achievement, and religious service attendance. Stoic individualists were characterized by low extraversion, sensation seeking, and openness. Thrill-seeking socializers were characterized by high levels of sensation seeking and extraversion. Among females, thrill-seeking socializers were significantly more likely than safe responsibles to have used any substance in the prior 30 days (odds ratio [OR] = 2.04, 95% confidence interval [CI] [1.65, 2.52]; Nagelkerke R 2 = .084). Among males, stoic individualists (OR = 1.50, CI [1.08, 2.08]) and thrill-seeking socializers (OR = 1.53, CI [1.09, 2.13]) were more likely than safe responsibles to have used substances in the past 30 days (Nagelkerke R 2 : .109). Psychographic segmentation can identify young adult subgroups with differing psychographic and substance use profiles and inform health campaigns and messaging targeting youth.

  10. Method for determining immunochemical substances

    International Nuclear Information System (INIS)

    O'connor, J.

    1980-01-01

    Drawing a method for detecting and measuring a predetermined specifically-bindable immunochemical substance in a liquid sample in a cuvette, comprising the steps of: (A) providing, in an immunoassay technique for the liquid sample in said cuvette, a component comprising a suspension of particles which may be agglutinated or insolubilized in relationship to the presence and concentration of the immunochemical substance in the sample; and (B) determining the presence and concentration of the immunochemical substance by measuring the electromagnetic radiation transmission properties of the sample using a calibrated radiation-measuring apparatus, said apparatus comprising: (1) a suitable electromagnetic radiation source capable of providing radiation at wavelengths equal to or less than the mean diameter of said particles; (2) means for concentrating and collimating radiation from the electromagnetic radiation source to form a beam; (3) means for filtering the beam to (I) eliminate radiation having wavelengths greater than the means diameter of the particles and (II) transmit radiation, which radiation has a range, whereby the upper wavelength is equal to or below the mean diameter of the particles, and the range is of at least about 100nm; (4) means for (I) positioning a sample-containing cuvette and for (II) allowing the filtered beam incident on the cuvette to be transmitted through the cuvette and sample, and for (III) receiving a portion of the filtered beam transmitted through the sample at two or more predetermined angles with respect to the beam; and (5) means for detecting and measuring the portion of the beam transmitted at a predetermined angle

  11. Inherently safe passive gas monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Cordaro, Joseph V.; Bellamy, John Stephen; Shuler, James M.; Shull, Davis J.; Leduc, Daniel R.

    2016-09-06

    Generally, the present disclosure is directed to gas monitoring systems that use inductive power transfer to safely power an electrically passive device included within a nuclear material storage container. In particular, the electrically passive device can include an inductive power receiver for receiving inductive power transfer through a wall of the nuclear material storage container. The power received by the inductive power receiver can be used to power one or more sensors included in the device. Thus, the device is not required to include active power generation components such as, for example, a battery, that increase the risk of a spark igniting flammable gases within the container.

  12. Managing radioactive waste safely. Engaging Scotland

    International Nuclear Information System (INIS)

    Elrick, D.; Boyes, L.; McCormick, J.

    2002-01-01

    The report presents findings from a study to explore how best to engage the public and other stakeholders in decision-making processes on the safe management of radioactive waste. Scottish Council Foundation conducted extended focus groups with the Scottish public in 4 locations, as well as group and one-to-one interviews with stakeholders from the nuclear industry, environment non-governmental organisations (NGOs), bodies experienced in using other public engagement methods, Community Planning partners and media reporters. A review of literature on public involvement in radioactive waste issues and public engagement more generally was also conducted

  13. The journey from safe yield to sustainability.

    Science.gov (United States)

    Alley, William M; Leake, Stanley A

    2004-01-01

    Safe-yield concepts historically focused attention on the economic and legal aspects of ground water development. Sustainability concerns have brought environmental aspects more to the forefront and have resulted in a more integrated outlook. Water resources sustainability is not a purely scientific concept, but rather a perspective that can frame scientific analysis. The evolving concept of sustainability presents a challenge to hydrologists to translate complex, and sometimes vague, socioeconomic and political questions into technical questions that can be quantified systematically. Hydrologists can contribute to sustainable water resources management by presenting the longer-term implications of ground water development as an integral part of their analyses.

  14. Safe handling of plutonium: a panel report

    Energy Technology Data Exchange (ETDEWEB)

    1974-01-01

    This guide results from a meeting of a Panel of Experts held by the International Atomic Energy Agency on 8 to 12 November 1971. It is directed to workers in research laboratories handling plutonium in gram amounts. Contents: aspects of the physical and chemical properties of plutonium; metabolic features of plutonium; facility design features for safe handling of plutonium (layout of facility, working zones, decontamination room, etc.); glove boxes; health surveillance (surveillance of environment and supervision of workers); emergencies; organization. Annexes: types of glove boxes; tables; mobile ..cap alpha.. air sampler; aerosol monitor; bio-assay limits of detection; examples of contamination control monitors.

  15. A Safe Protocol for Amalgam Removal

    Directory of Open Access Journals (Sweden)

    Dana G. Colson

    2012-01-01

    Full Text Available Today's environment has different impacts on our body than previous generations. Heavy metals are a growing concern in medicine. Doctors and individuals request the removal of their amalgam (silver mercury restorations due to the high mercury content. A safe protocol to replace the silver mercury filling will ensure that there is minimal if any absorption of materials while being removed. Strong alternative white composite and lab-processed materials are available today to create a healthy and functioning mouth. Preparation of the patient prior to the procedure and after treatment is vital to establish the excretion of the mercury from the body.

  16. Safe 15 Terawatt of Temelin NPP

    International Nuclear Information System (INIS)

    Sula, M.

    2010-01-01

    In this work author presents a project Safe 15 Terawatt realised on the Temelin NPP. This project is one of the eight key projects of the CEZ group, associated in the 'Programme of efficiency'. The project started in June 2007 with long-term goals for horizon of year 2012. The safety indicators will be reached of the first quarter level of world's nuclear power plant - by the end of the first decade. By the end of year 2012 we will have achieved annual production of 15 billion kWh - in the Czech Republic: 15 Terawatt.

  17. Substance Use, Violence, and Antiretroviral Adherence: A Latent Class Analysis of Women Living with HIV in Canada.

    Science.gov (United States)

    Carter, Allison; Roth, Eric Abella; Ding, Erin; Milloy, M-J; Kestler, Mary; Jabbari, Shahab; Webster, Kath; de Pokomandy, Alexandra; Loutfy, Mona; Kaida, Angela

    2018-03-01

    We used latent class analysis to identify substance use patterns for 1363 women living with HIV in Canada and assessed associations with socio-economic marginalization, violence, and sub-optimal adherence to combination antiretroviral therapy (cART). A six-class model was identified consisting of: abstainers (26.3%), Tobacco Users (8.81%), Alcohol Users (31.9%), 'Socially Acceptable' Poly-substance Users (13.9%), Illicit Poly-substance Users (9.81%) and Illicit Poly-substance Users of All Types (9.27%). Multinomial logistic regression showed that women experiencing recent violence had significantly higher odds of membership in all substance use latent classes, relative to Abstainers, while those reporting sub-optimal cART adherence had higher odds of being members of the poly-substance use classes only. Factors significantly associated with Illicit Poly-substance Users of All Types were sexual minority status, lower income, and lower resiliency. Findings underline a need for increased social and structural supports for women who use substances to support them in leading safe and healthy lives with HIV.

  18. Identification of antifungal activity substances on seedborn disease from garlic and taxus extracts

    Energy Technology Data Exchange (ETDEWEB)

    Chung, I.M.; Paik, S.B. [Konkuk University, Seoul (Korea, Republic of)

    1999-02-01

    Antifungal substances were isolated and identified from garlic and taxus extracts to develop safe and broad fungicide. The inhibitory effect of seedborn disease of sesame, pepper, radish, chinese cabbage by formulation of antifungal substances was investigated. The antifungal substance isolated through column chromatography from garlic and taxus extracts was confirmed by GC-MS as allicin (C{sub 6}H{sub 10}OS{sub 2}) and taxol(C{sub 47}H{sub 51}NO{sub 14}) and the quantified content from each extracts by HPLC analysis was 0.62%, 0.29%, respectively. The formulation composed of garlic and taxus extracts controlled effectively the seedborn fungi tested in this study at 10X dilution, but at 100X dilution the inhibitory effect decreased. Phytotoxicity of these formulations did not recognized. 22 refs., 6 figs., 5 tabs.

  19. Waste Issues Associated with the Safe Movement of Hazardous Chemicals

    International Nuclear Information System (INIS)

    Dare, J. H.; Cournoyer, M. E.

    2002-01-01

    Moving hazardous chemicals presents the risk of exposure for workers engaged in the activity and others that might be in the immediate area. Adverse affects are specific to the chemicals and can range from minor skin, eye, or mucous membrane irritation, to burns, respiratory distress, nervous system dysfunction, or even death. A case study is presented where in the interest of waste minimization; original shipping packaging was removed from a glass bottle of nitric acid, while moving corrosive liquid through a security protocol into a Radiological Control Area (RCA). During the transfer, the glass bottle broke. The resulting release of nitric acid possibly exposed 12 employees with one employee being admitted overnight at a hospital for observation. This is a clear example of administrative controls to reduce the generation of suspect radioactive waste being implemented at the expense of employee health. As a result of this event, material handling procedures that assure the safe movement of hazardous chemicals through a security protocol into a radiological control area were developed. Specifically, hazardous material must be transferred using original shipping containers and packaging. While this represents the potential to increase the generation of suspect radioactive waste in a radiological controlled area, arguments are presented that justify this change. Security protocols for accidental releases are also discussed. In summary, the 12th rule of ''Green Chemistry'' (Inherently Safer Chemistry for Accident Prevention) should be followed: the form of a substance used in a chemical process (Movement of Hazardous Chemicals) should be chosen to minimize the potential for chemical accidents, including releases

  20. Waste Issues Associated with the Safe Movement of Hazardous Chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Dare, J. H.; Cournoyer, M. E.

    2002-02-26

    Moving hazardous chemicals presents the risk of exposure for workers engaged in the activity and others that might be in the immediate area. Adverse affects are specific to the chemicals and can range from minor skin, eye, or mucous membrane irritation, to burns, respiratory distress, nervous system dysfunction, or even death. A case study is presented where in the interest of waste minimization; original shipping packaging was removed from a glass bottle of nitric acid, while moving corrosive liquid through a security protocol into a Radiological Control Area (RCA). During the transfer, the glass bottle broke. The resulting release of nitric acid possibly exposed 12 employees with one employee being admitted overnight at a hospital for observation. This is a clear example of administrative controls to reduce the generation of suspect radioactive waste being implemented at the expense of employee health. As a result of this event, material handling procedures that assure the safe movement of hazardous chemicals through a security protocol into a radiological control area were developed. Specifically, hazardous material must be transferred using original shipping containers and packaging. While this represents the potential to increase the generation of suspect radioactive waste in a radiological controlled area, arguments are presented that justify this change. Security protocols for accidental releases are also discussed. In summary, the 12th rule of ''Green Chemistry'' (Inherently Safer Chemistry for Accident Prevention) should be followed: the form of a substance used in a chemical process (Movement of Hazardous Chemicals) should be chosen to minimize the potential for chemical accidents, including releases.

  1. Storage of hazardous substances in bonded warehouses

    International Nuclear Information System (INIS)

    Villalobos Artavia, Beatriz

    2008-01-01

    A variety of special regulations exist in Costa Rica for registration and transport of hazardous substances; these set the requirements for entry into the country and the security of transport units. However, the regulations mentioned no specific rules for storing hazardous substances. Tax deposits have been the initial place where are stored the substances that enter the country.The creation of basic rules that would be regulating the storage of hazardous substances has taken place through the analysis of regulations and national and international laws governing hazardous substances. The regulatory domain that currently exists will be established with a field research in fiscal deposits in the metropolitan area. The storage and security measures that have been used by the personnel handling the substances will be identified to be putting the reality with that the hazardous substances have been handled in tax deposits. A rule base for the storage of hazardous substances in tax deposits can be made, protecting the safety of the environment in which are manipulated and avoiding a possible accident causing a mess around. The rule will have the characteristics of the storage warehouses hazardous substances, such as safety standards, labeling standards, infrastructure features, common storage and transitional measures that must possess and meet all bonded warehouses to store hazardous substances. (author) [es

  2. Prepare to protect: Operating and maintaining a tornado safe room.

    Science.gov (United States)

    Herseth, Andrew; Goldsmith-Grinspoon, Jennifer; Scott, Pataya

    2017-06-01

    Operating and maintaining a tornado safe room can be critical to the effective continuity of business operations because a firm's most valuable asset is its people. This paper describes aspects of operations and maintenance (O&M) for existing tornado safe rooms as well as a few planning and design aspects that affect the ultimate operation of a safe room for situations where a safe room is planned, but not yet constructed. The information is based on several Federal Emergency Management Agency safe room publications that provide guidance on emergency management and operations, as well as the design and construction of tornado safe rooms.

  3. Safe transport of radioactive material. 3. ed

    International Nuclear Information System (INIS)

    2002-01-01

    The IAEA has developed a standardized approach to transport safety training as a means of helping Member States to implement the Transport Regulations. The training manual is an anchor of this standardized approach to training: it contains all the topics presented in the sequential order recommended by the IAEA for the student to gain a thorough understanding of the body of knowledge that is needed to ensure that radioactive material ranked as Class 7 in the United Nations' nomenclature for dangerous goods - is transported safely. The explanations in the text refer, where needed, to the appropriate requirements in the IAEA's Transport Regulations; additional useful information is also provided. Thus, the training manual in addition to the Transport Regulations and their supporting documents is used by the IAEA as the basis for delivering all of its training courses on the safe transport of radioactive material. Enclosed with the training manual is a CD-ROM that contains the text of the manual as well as the visual aids that are used at the IAEA's training courses. The following topics are covered: review of radioactivity and radiation; review of radiation protection principles; regulatory terminology; basic safety concepts: materials and packages; activity limits and material restrictions; selection of optimal package type; test procedures: material and packages; requirements for transport; control of material in transport; fissile material: regulatory requirements and operational aspects; quality assurance; national competent authority; additional regulatory constraints for transport; international liability and insurance; emergency planning and preparedness; training; services provided by the IAEA

  4. Risk management for assuring safe drinking water.

    Science.gov (United States)

    Hrudey, Steve E; Hrudey, Elizabeth J; Pollard, Simon J T

    2006-12-01

    Millions of people die every year around the world from diarrheal diseases much of which is caused by contaminated drinking water. By contrast, drinking water safety is largely taken for granted by many citizens of affluent nations. The ability to drink water that is delivered into households without fear of becoming ill may be one of the key defining characteristics of developed nations in relation to the majority of the world. Yet there is well-documented evidence that disease outbreaks remain a risk that could be better managed and prevented even in affluent nations. A detailed retrospective analysis of more than 70 case studies of disease outbreaks in 15 affluent nations over the past 30 years provides the basis for much of our discussion [Hrudey, S.E. and Hrudey, E.J. Safe Drinking Water--Lessons from Recent Outbreaks in Affluent Nations. London, UK: IWA Publishing; 2004.]. The insights provided can assist in developing a better understanding within the water industry of the causes of drinking water disease outbreaks, so that more effective preventive measures can be adopted by water systems that are vulnerable. This preventive feature lies at the core of risk management for the provision of safe drinking water.

  5. Safe transport of radioactive material. 3. ed

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-12-01

    The IAEA has developed a standardized approach to transport safety training as a means of helping Member States to implement the Transport Regulations. The training manual is an anchor of this standardized approach to training: it contains all the topics presented in the sequential order recommended by the IAEA for the student to gain a thorough understanding of the body of knowledge that is needed to ensure that radioactive material ranked as Class 7 in the United Nations' nomenclature for dangerous goods - is transported safely. The explanations in the text refer, where needed, to the appropriate requirements in the IAEA's Transport Regulations; additional useful information is also provided. Thus, the training manual in addition to the Transport Regulations and their supporting documents is used by the IAEA as the basis for delivering all of its training courses on the safe transport of radioactive material. Enclosed with the training manual is a CD-ROM that contains the text of the manual as well as the visual aids that are used at the IAEA's training courses. The following topics are covered: review of radioactivity and radiation; review of radiation protection principles; regulatory terminology; basic safety concepts: materials and packages; activity limits and material restrictions; selection of optimal package type; test procedures: material and packages; requirements for transport; control of material in transport; fissile material: regulatory requirements and operational aspects; quality assurance; national competent authority; additional regulatory constraints for transport; international liability and insurance; emergency planning and preparedness; training; services provided by the IAEA.

  6. Light water ultra-safe plant concept

    International Nuclear Information System (INIS)

    Klevans, E.

    1989-01-01

    Since the accident at Three Mile Island (TMI), Penn State Nuclear Engineering Department Faculty and Staff have considered various methods to improve already safe reactor designs and public perception of the safety of Nuclear Power. During 1987 and 1988, the Department of Energy provided funds to the Nuclear Engineering Department at Penn State to investigate a plant reconfiguration originated by M.A. Schultz called ''The Light Water Ultra-Safe Plant Concept''. This report presents a final summary of the project with references to several masters' theses and addendum reports for further detail. The two year research effort included design verification with detailed computer simulation of: (a) normal operation characteristics of the unique pressurizing concept, (b) severe transients without loss of coolant, (c) combined primary and secondary system modeling, and (d) small break and large break loss of coolant accidents. Other studies included safety analysis, low power density core design, and control system design to greatly simplify the control room and required operator responses to plant upset conditions. The overall conclusion is that a reconfigured pressurized water reactor can achieve real and perceived safety improvements. Additionally, control system research to produce greatly simplified control rooms and operator requirements should be continued in future projects

  7. The Conceptual Design of Innovative Safe PWR

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Han-Gon [Centural Research Institute, Daejeon (Korea, Republic of); Heo, Sun [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

    2016-10-15

    Most of countries operating NPPs have been performed post-Fukushima improvements as short-term countermeasure to enhance the safety of operating NPPs. Separately, vendors have made efforts on developing passive safety systems as long-term and ultimate countermeasures. AP1000 designed by Westinghouse Electric Company has passive safety systems including the passive emergency core cooling system (PECCS), the passive residual heat removal system (PRHRS), and the passive containment cooling system (PCCS). ESBWR designed by GE-Hitachi also has passive safety systems consisting of the isolation condenser system, the gravity driven cooling system and the PCCS. Other countries including China and Russia have made efforts on developing passive safety systems for enhancing the safety of their plants. In this paper, we summarize the design goals and main design feature of innovative safe PWR, iPOWER which is standing for Innovative Passive Optimized World-wide Economical Reactor, and show the developing status and results of research projects. To mitigate an accident without electric power and enhance the safety level of PWR, the conceptual designs of passive safety system and innovative safe PWR have been performed. It includes the PECCS for core cooling and the PCCS for containment cooling. Now we are performing the small scale and separate effect tests for the PECCS and the PCCS and preparing the integral effect test for the PECCS and real scale test for the PCCS.

  8. Social Influence and Safe Behavior in Manufacturing

    DEFF Research Database (Denmark)

    Hald, Kim Sundtoft

    2018-01-01

    This research presents a model designed to explore the cognitive and social mechanisms that mediate the relationship between organizational safety climate and safety behaviors. Specifically the presented research demonstrates the usefulness of Sussmann and Vecchio (1982) social influence interpre......This research presents a model designed to explore the cognitive and social mechanisms that mediate the relationship between organizational safety climate and safety behaviors. Specifically the presented research demonstrates the usefulness of Sussmann and Vecchio (1982) social influence...... interpretation of worker motivation to understand safety motivation. Survey data was collected from 428 employees in seven factories within the electronics industry in China. The data were analyzed using structural modelling. The results suggest that factory workers with more knowledge about the products...... that the total effects of a factory workers experience with safety and health problems seems to affect safe work behavior negatively, and that this is caused by a decrease in confidence and abilities to work safely. In relation to practical implications the present study demonstrate how manufacturing managers...

  9. Nonspecific abdominal pain is a safe diagnosis.

    Science.gov (United States)

    Pennel, David John Laurie; Goergen, Nina; Driver, Chris P

    2014-11-01

    The aim of this study is to assess if a clinical diagnosis of nonspecific abdominal pain (NSAP) is safe and if patients with this initial diagnosis are likely to require further investigation or surgical intervention. 3323 patients admitted with NSAP from July 1990 to September 2012 utilizing a prospective database of all surgical admissions were included. Readmission over the period of the study and specifically within 30 days of their initial presentation was identified together with any invasive investigation or surgical intervention. 319 children (9.6%) were subsequently readmitted with abdominal pain at some point during the study period. Of these, 78 (2.3%) were readmitted within 30 days. 118 (3.5%) children subsequently had an operation or invasive investigation some point following their initial admission. Of these 33 (0.6%) had the procedure within 3 months of the initial admission. 13 patients had an appendicectomy within 3 months of the initial presentation. Of these histology confirmed appendicitis in 8 patients. This gives an overall incidence of "missed" appendicitis of 0.2 % (8/3323). This study confirms that a clinical diagnosis of nonspecific abdominal pain (NSAP) is safe in a pediatric population and the risk of "missing" appendicitis is only 0.2%. Patients and/or parents can be confidently reassured that the risk of missing organic pathology is very low. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Nuclear hydrogen production and its safe handling

    International Nuclear Information System (INIS)

    Chung, Hongsuk; Paek, Seungwoo; Kim, Kwang-Rag; Ahn, Do-Hee; Lee, Minsoo; Chang, Jong Hwa

    2003-01-01

    An overview of the hydrogen related research presently undertaken at the Korea Atomic Energy Research Institute are presented. These encompass nuclear hydrogen production, hydrogen storage, and the safe handling of hydrogen, High temperature gas-cooled reactors can play a significant role, with respect to large-scale hydrogen production, if used as the provider of high temperature heat in fossil fuel conversion or thermochemical cycles. A variety of potential hydrogen production methods for high temperature gas-cooled reactors were analyzed. They are steam reforming of natural gas, thermochemical cycles, etc. The produced hydrogen should be stored safely. Titanium metal was tested primarily because its hydride has very low dissociation pressures at normal storage temperatures and a high capacity for hydrogen, it is easy to prepare and is non-reactive with air in the expected storage conditions. There could be a number of potential sources of hydrogen evolution risk in a nuclear hydrogen production facility. In order to reduce the deflagration detonation it is necessary to develop hydrogen control methods that are capable of dealing with the hydrogen release rate. A series of experiments were conducted to assess the catalytic recombination characteristics of hydrogen in an air stream using palladium catalysts. (author)

  11. Inherently safe characteristics of nuclear reactors

    International Nuclear Information System (INIS)

    1989-01-01

    This report is based on a detailed study which was carried out by Colenco (a company of the Motor-Columbus Group) on behalf of the Commission of the European Communities (CEC). It presents a summary of this study and concentrates more on the generic issues involved in the subject of inherent safety in nuclear power plants. It is assumed that the reader is reasonably familiar with the design outline of the systems included in the report. The report examines the role of inherent design features in achieving the safety of nuclear power plants as an alternative to the practice, which is largely followed in current reactors, of achieving safety by the addition of engineered safety features. The report examines current reactor systems to identify the extent to which their characteristics are either already inherently safe or, on the other hand, have inherent characteristics that require protective action to be taken. It then considers the advantages of introducing design changes to improve their inherent safety characteristics. Next, it looks at some new reactor types for which claims of inherent safety are made to see to what extent these claims are justified. The general question is then considered whether adoption of the inherently safe reactors would give advantages (by reducing risk in real terms or by improving the public acceptability of nuclear power) which are sufficient to offset the expected high costs and the technical risks associated with any new technology

  12. Is irradiation of food stuffs safe?

    International Nuclear Information System (INIS)

    Maheshwari, Raaz K.; Yadav, Rajesh K.

    2014-01-01

    Many advanced and several developing countries have abundant supplies of fresh, safe and nutritious food stuffs. Yet, despite the many precautions and processes in place to ensure safe food supply, microbial contamination is still a concern. There are a number of food processing tools available that provide additional protection for the food we consume. One very promising tool is food irradiation, which is a process of imparting ionizing energy to food to kill microorganisms. Food irradiation is the process of exposing food to a controlled source of ionising radiation for the purposes of reduction of microbial Ioad, destruction of pathogens, extension of product shelf life, and/or disinfection of produce. The term irradiation often evokes fears of nuclear radioactivity and cancer among consumers. The process seems frightening because it is powerful and invisible. Consequently questions and concerns exist particularly about the safety or wholesomeness of irradiated food. The paper highlights food irradiation as a food safety measure and the issues of concerns for consumers. (author)

  13. Power source with spark-safe outlet

    Energy Technology Data Exchange (ETDEWEB)

    Tsesarenko, N P; Alekhin, A V

    1982-01-01

    The invention refers to the technique of electrical monitoring and control in systems operating in a spark-safe medium (for example, in coal mines). A more accurate area of application is mobile objects with autonomous source of electricity (mine diesel locomotives, battery electric locomotives etc.). The purpose of the invention is to simplify and to improve the reliability of the planned device, and also to expand the area of application for conditions when it is powered from an autonomous generator of direct voltage. This goal is achieved because the power source with spark-safe outlet (the source contains a thyristor of advance disconnection, connected by anode to the delimiting throttle, one outlet of which is connected to the capacitor included between the controlling electrode and the anode of the thyristor, and the capacitor is connected through the resistor parallel to the outlet clamps of the source, while the thyristor of emergency protection connected parallel to the inlet clamps of the power source) is additionally equipped with a current sensor, hercon, transistor key (included in series in the power circuit) and optron, whose emitter is connected parallel to the current sensor connected in series to the inlet of the power source, while the receiver of the optron is connected in a circuit for controlling the thyristor of emergency protection. Hercon is built into the core of the delimiting throttle and is connected to the circuit for controlling the transistor key.

  14. The safe use of radiation sources

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    As a means of promoting safety in the use of radiation sources, as well as encouraging consistency in regulatory control, the IAEA has from time to time organized training courses with the co-operation of Member State governments and organizations, to inform individuals from developing countries with appropriate responsibilities on the provisions for the safe use and regulation of radiation sources. Three such courses on the safe use of radiation sources have been held in both the USA, with the co-operation of the United States Government, and in Dublin, Ireland, with the co-operation of the Irish Government. The Training Course on the Safe Use and Regulation of Radiation Sources has been successfully given to over 77 participants from over 30 countries during the last years. The course is aimed at providing a basis of radiation protection knowledge in all aspects of the uses of radiation and of radiation sources that are used today. It is the intention of this course to provide a systematic enhancement of radioisotope safety in countries with developing radiological programmes through a core group of national authorities. The IAEA's training programmes provide an excellent opportunity for direct contact with lecturers that have extensive experience in resolving issues faced by developing countries and in providing guidance documents useful in addressing their problems. This document uses this collective experience and provides valuable technical information regarding the safety aspects of the uses not only of sealed and unsealed sources of radiation, but also for those machines that produce ionizing radiation. The first of these training courses, 'Safety and Regulation of Unsealed Sources' was held in Dublin, Ireland, June through July 1989 with the co-operation of the Nuclear Energy Board and Trinity College. This was an interregional training course, the participants came from all over the world. The second and third interregional courses, 'Safety and Regulation

  15. The safe use of radiation sources

    International Nuclear Information System (INIS)

    1995-01-01

    As a means of promoting safety in the use of radiation sources, as well as encouraging consistency in regulatory control, the IAEA has from time to time organized training courses with the co-operation of Member State governments and organizations, to inform individuals from developing countries with appropriate responsibilities on the provisions for the safe use and regulation of radiation sources. Three such courses on the safe use of radiation sources have been held in both the USA, with the co-operation of the United States Government, and in Dublin, Ireland, with the co-operation of the Irish Government. The Training Course on the Safe Use and Regulation of Radiation Sources has been successfully given to over 77 participants from over 30 countries during the last years. The course is aimed at providing a basis of radiation protection knowledge in all aspects of the uses of radiation and of radiation sources that are used today. It is the intention of this course to provide a systematic enhancement of radioisotope safety in countries with developing radiological programmes through a core group of national authorities. The IAEA's training programmes provide an excellent opportunity for direct contact with lecturers that have extensive experience in resolving issues faced by developing countries and in providing guidance documents useful in addressing their problems. This document uses this collective experience and provides valuable technical information regarding the safety aspects of the uses not only of sealed and unsealed sources of radiation, but also for those machines that produce ionizing radiation. The first of these training courses, 'Safety and Regulation of Unsealed Sources' was held in Dublin, Ireland, June through July 1989 with the co-operation of the Nuclear Energy Board and Trinity College. This was an interregional training course, the participants came from all over the world. The second and third interregional courses, 'Safety and Regulation

  16. Implementation of the NANoREG Safe-by-Design approach for different nanomaterial applications

    International Nuclear Information System (INIS)

    Micheletti, C; Roman, M; Tedesco, E; Olivato, I; Benetti, F

    2017-01-01

    The Safe-by-Design (SbD) concept is already in use in different industrial sectors as an integral part of the innovation process management. However, the adopted approach is often limited to design solutions aiming at hazard reduction. Safety is not always considered during the innovation process, mainly due to the lack of knowledge (e.g. in small and medium companies, SMEs) and the lack of dialogue between actors along the innovation chain. The net result is that safety is considered only at the end of the innovation process at the market authorization phase, with potential loss of time and money. This is especially valid for manufactured nanomaterials (MNM) for which the regulatory context is not completely developed, and the safety knowledge is not readily available. In order to contribute to a sustainable innovation process in the nanotechnology field by maximising both benefits and safety, the NANoREG project developed a Safe Innovation approach, based on two elements: the Safe-by-Design approach which aims at including risk assessment into all innovation stages; and the Regulatory Preparedness, focused on the dialogue with stakeholders along the innovation chain. In this work we present some examples about the implementation in our Laboratory of this approach for different MNM applications, covering different steps of the innovation chain. The case studies include: the feasibility study of a medical device including substances, for topical application; the testing of two potential nanotech solutions for the consolidation of cultural heritage artifacts; the testing of coatings already on the market for other uses, which was tested as food contact materials (FCM) to evaluate the conformity to food applications. These three examples represent a good opportunity to show the importance of NANoREG SbD and Safe Innovation Approach in general, for developing new nanotechnology-based products, also highlighting the crucial role of EU ProSafe project in promoting this

  17. Implementation of the NANoREG Safe-by-Design approach for different nanomaterial applications

    Science.gov (United States)

    Micheletti, C.; Roman, M.; Tedesco, E.; Olivato, I.; Benetti, F.

    2017-06-01

    The Safe-by-Design (SbD) concept is already in use in different industrial sectors as an integral part of the innovation process management. However, the adopted approach is often limited to design solutions aiming at hazard reduction. Safety is not always considered during the innovation process, mainly due to the lack of knowledge (e.g. in small and medium companies, SMEs) and the lack of dialogue between actors along the innovation chain. The net result is that safety is considered only at the end of the innovation process at the market authorization phase, with potential loss of time and money. This is especially valid for manufactured nanomaterials (MNM) for which the regulatory context is not completely developed, and the safety knowledge is not readily available. In order to contribute to a sustainable innovation process in the nanotechnology field by maximising both benefits and safety, the NANoREG project developed a Safe Innovation approach, based on two elements: the Safe-by-Design approach which aims at including risk assessment into all innovation stages; and the Regulatory Preparedness, focused on the dialogue with stakeholders along the innovation chain. In this work we present some examples about the implementation in our Laboratory of this approach for different MNM applications, covering different steps of the innovation chain. The case studies include: the feasibility study of a medical device including substances, for topical application; the testing of two potential nanotech solutions for the consolidation of cultural heritage artifacts; the testing of coatings already on the market for other uses, which was tested as food contact materials (FCM) to evaluate the conformity to food applications. These three examples represent a good opportunity to show the importance of NANoREG SbD and Safe Innovation Approach in general, for developing new nanotechnology-based products, also highlighting the crucial role of EU ProSafe project in promoting this

  18. Is propolis safe as an alternative medicine?

    Directory of Open Access Journals (Sweden)

    Maria Graça Miguel

    2011-01-01

    Full Text Available Propolis is a resinous substance produced by honeybees as defense against intruders. It has relevant therapeutic properties that have been used since ancient times. Nowadays, propolis is of increasing importance as a therapeutic, alone or included in many medicines and homeopathic products or in cosmetics. Propolis is produced worldwide and honeybees use the flora surrounding their beehives for its production. Therefore its chemical composition may change according to the flora. The phenolic and volatile fractions of propolis have been revised in the present study, as well as some of the biological properties attributed to this natural product. An alert is given about the need to standardize this product, with quality control. This has already been initiated by some authors, mainly in the propolis from the poplar-type. Only this product can constitute a good complementary and alternative medicine under internationally acceptable quality control.

  19. Criteria for safe working with iodine-125

    International Nuclear Information System (INIS)

    Linsley, G.S.

    1977-01-01

    Radio-immunoassay and other saturation assay tests involving the use of iodine-125 are finding wide application for the determination of hormone concentrations in biological fluids. In such tests, iodinations involving concentrations of a milli-curie per micro-litre are common. Iodine-125 presents a problem from the monitoring standpoint because of its low energy photon emission (27 and 35 keV). Iodine is preferentially taken up by the thyroid gland and work involving moderate amounts of radio-iodine may give rise to a significant hazard in an accident situation. The general precautions which should be taken in work with unsealed radioactive substances are briefly summarized, working limits for iodine-125 are identified, and methods of personal protection and monitoring in an emergency situation described. (author)

  20. Regulations for the safe transport of radioactive material

    International Nuclear Information System (INIS)

    1995-01-01

    Regulations and rules for the safe transport of radioactive materials by all kinds of conveyance are offered. Different types of packages and the conditions associated with the methods of safe packaging are given

  1. Safety Case for Safe-store

    International Nuclear Information System (INIS)

    Woollam, Paul B.

    2002-01-01

    Magnox Electric plc (Magnox), a wholly owned subsidiary of BNFL, owns 26 gas-cooled, graphite-moderated units on 11 sites in the UK. Eight units have been permanently shutdown and the remainder will shut this decade in a currently declared closure programme. The first of these reactors went to power in 1952 and the fleet has generated typically 9% of the UK's electricity during the last five decades. In accordance with UK Government policy, BNFL aims for a systematic and progressive reduction in hazards on its decommissioning sites. The end-point of the decommissioning process is that the reactors will be dismantled and their sites de-licensed. This will be done through minimising both the risks to the public, workers and the environment and also the lifetime cost, consistent with world class safety. There will be passive safe storage during deferment periods and it is BNFL's clear intent that the reactors will not be Safe-stored indefinitely. The main hazard associated with any decommissioned nuclear site is the spent fuel. Hence the reactors will be de-fuelled as soon as practicable after shutdown. After this work is complete, Cs-137 contaminated plant (e.g. fuel pools, effluent plant, and drains) will be dismantled when it is no longer needed. All other plant and buildings will also be dismantled when they are no longer needed, except for the reactor buildings which will be put into passive safe storage. Co-60 contaminated plant, such as steam generators, will be dismantled with the reactors. The reactors will be dismantled in a sequenced programme, with a notional start time around 100 years from shutdown. Magnox Electric is ensuring that the reactors and primary circuits on all its sites are well characterised. We have carried out a detailed, peer reviewed hazard identification on the lead site from which we have generated a rolling 25-year basic safety case. We have then searched for cliff edge effects and possible long-term changes to generate the 100-year

  2. National substance use patterns on Twitter.

    Directory of Open Access Journals (Sweden)

    Hsien-Wen Meng

    Full Text Available We examined openly shared substance-related tweets to estimate prevalent sentiment around substance use and identify popular substance use activities. Additionally, we investigated associations between substance-related tweets and business characteristics and demographics at the zip code level.A total of 79,848,992 tweets were collected from 48 states in the continental United States from April 2015-March 2016 through the Twitter API, of which 688,757 were identified as being related to substance use. We implemented a machine learning algorithm (maximum entropy text classifier to estimate sentiment score for each tweet. Zip code level summaries of substance use tweets were created and merged with the 2013 Zip Code Business Patterns and 2010 US Census Data.Quality control analyses with a random subset of tweets yielded excellent agreement rates between computer generated and manually generated labels: 97%, 88%, 86%, 75% for underage engagement in substance use, alcohol, drug, and smoking tweets, respectively. Overall, 34.1% of all substance-related tweets were classified as happy. Alcohol was the most frequently tweeted substance, followed by marijuana. Regression results suggested more convenience stores in a zip code were associated with higher percentages of tweets about alcohol. Larger zip code population size and higher percentages of African Americans and Hispanics were associated with fewer tweets about substance use and underage engagement. Zip code economic disadvantage was associated with fewer alcohol tweets but more drug tweets.The patterns in substance use mentions on Twitter differ by zip code economic and demographic characteristics. Online discussions have great potential to glorify and normalize risky behaviors. Health promotion and underage substance prevention efforts may include interactive social media campaigns to counter the social modeling of risky behaviors.

  3. Substance Use among Adolescent Mothers: A Review.

    Science.gov (United States)

    Chapman, Shawna L Carroll; Wu, Li-Tzy

    2013-05-01

    Maternal substance abuse is a critical problem, and adolescent mothers appear to be at high risk for such behaviors. We review studies on postpartum adolescent substance use to explore the extent of this problem and avenues for new research. Authors screened 1,300 studies, identifying 12 articles on substance use among postpartum adolescent mothers for this review. Adolescent mothers reported greater substance use before pregnancy compared to other adolescent females. Although some adolescents continued substance use during pregnancy, most stopped using only to resume within six months after birth. Comparisons of use to national samples of nulliparous adolescent females showed a higher prevalence of substance use in this population. Substances used often varied by race/ethnicity, with white mothers more likely to smoke cigarettes and use marijuana, and Black mothers more likely than whites to drink and use drugs. Of all identified studies, only one focused on Hispanics. Beliefs about drug use grew less negative as girls transitioned from pregnancy to parenthood. As they transitioned to adulthood, substance use remained prevalent and stable. Psychological distress and low self-esteem appeared to influence continued use. Friends' cigarette smoking predicted early initiation of and persistent smoking, while increased education predicted quitting. Early initiation of substances often predicted problem behaviors. Adolescent mothers are a vulnerable population, implicating use of problem behavior theory or the self-medication hypothesis in future research. Multiple avenues for new studies are needed to help identify effective treatment and intervention for this understudied population.

  4. Humic Substances in waters for supply

    International Nuclear Information System (INIS)

    Camargo Valero, Miller; Cruz Torres, Luis Eduardo

    1999-01-01

    The humic substances make part of the degradation products of the organic matter of the soil and they are incorporate to the superficial waters for the action of laundry that they carry out by the superficial waters. These substances have been recognized as precursors in the formation of the disinfections sub-products, with free chlorine in treatment of drinkable water plants. The disinfections sub-product and the compound organic halogens, they have been classified potentially in human as cancerigenic substances, and therefore the interest in knowing more about the precursors substances, mechanisms of formation of disinfections sub-products, national situation and methods to diminish their formation

  5. Refractory organic substances in the environment

    National Research Council Canada - National Science Library

    Frimmel, F. H

    2002-01-01

    ... and its Quality Control in Fractions of Refractory Organic Substances and the Corresponding Original Water Samples 39 Introduction 39 Description of Analytical Methods 41 Sample Treatment 41 Fl...

  6. Inherently safe in situ uranium recovery

    Science.gov (United States)

    Krumhansl, James L; Brady, Patrick V

    2014-04-29

    An in situ recovery of uranium operation involves circulating reactive fluids through an underground uranium deposit. These fluids contain chemicals that dissolve the uranium ore. Uranium is recovered from the fluids after they are pumped back to the surface. Chemicals used to accomplish this include complexing agents that are organic, readily degradable, and/or have a predictable lifetime in an aquifer. Efficiency is increased through development of organic agents targeted to complexing tetravalent uranium rather than hexavalent uranium. The operation provides for in situ immobilization of some oxy-anion pollutants under oxidizing conditions as well as reducing conditions. The operation also artificially reestablishes reducing conditions on the aquifer after uranium recovery is completed. With the ability to have the impacted aquifer reliably remediated, the uranium recovery operation can be considered inherently safe.

  7. Safe transport of radioactive material. 4. ed

    International Nuclear Information System (INIS)

    2006-01-01

    The IAEA has been publishing Regulations for the Safe Transport of Radioactive Material since 1961. Meeting its statutory obligation to foster the exchange and training of scientists and experts in the field of peaceful uses of atomic energy, the IAEA has developed a standardized approach to transport safety training. This training manual is an anchor of the standardized approach to training. It is a compendium of training modules for courses related to the different aspects of safety of transport of radioactive material. Keeping in view the specific needs of the potential users, the manual includes material that can be used for a variety of training programmes of duration ranging from half-a-day to ten days, for specific audiences such as competent authority personnel, public authorities, emergency response personnel and cargo handlers

  8. Is renewable energy 100% environmentally safe

    International Nuclear Information System (INIS)

    Nasr, Ali Ahmed

    2006-01-01

    Renewable energy (RE) concerned are usually optimistic in introducing RE as environmentally safe resource. This might be reasonably acceptable when compared with conventional energy resources, there should be some side effects however. Those effects, and critics, when considered and possibly avoided, RE sources will be environmentally more acceptable and as a result will be appreciated by consumers. In this paper we try to investigate and point out some of these critics, and negative impacts by examining examples of some RE systems and how different solutions were tackled and partially managed. Through Re resources have advantages over other resources, when environmental issues are considered, there still exists, however, some negative impacts on the environment caused by RE resources. Present study showed that the above mentioned impacts can be reduced to some reasonable level.(Author)

  9. The safe road transport system approach

    Directory of Open Access Journals (Sweden)

    Vollpracht Hans-Joachim

    2016-07-01

    Full Text Available More than 1,24 million people die each year on the worlds roads and between 20 to 50 million suffer from nonfatal injuries. The UN Road Safety Collaboration Meetings under the leadership of WHO developed the Programme for the Decade of Actions for road safety taking nations into the responsibility of improving their accident figures by the five pillars of a national Road Safety Policy, safer Roads, safer Vehicles, safer Road Users and Post Crash Care. It is this Safe System Approach that takes into consideration the land use, infrastructure and transport planning, road user’s abilities and limitations and the close cooperation of all governmental and none governmental stakeholders involved.

  10. Vulnerabilities Classification for Safe Development on Android

    Directory of Open Access Journals (Sweden)

    Ricardo Luis D. M. Ferreira

    2016-06-01

    Full Text Available The global sales market is currently led by devices with the Android operating system. In 2015, more than 1 billion smartphones were sold, of which 81.5% were operated by the Android platform. In 2017, it is estimated that 267.78 billion applications will be downloaded from Google Play. According to Qian, 90% of applications are vulnerable, despite the recommendations of rules and standards for the safe software development. This study presents a classification of vulnerabilities, indicating the vulnerability, the safety aspect defined by the Brazilian Association of Technical Standards (Associação Brasileira de Normas Técnicas - ABNT norm NBR ISO/IEC 27002 which will be violated, which lines of code generate the vulnerability and what should be done to avoid it, and the threat agent used by each of them. This classification allows the identification of possible points of vulnerability, allowing the developer to correct the identified gaps.

  11. An inherently safe power reactor module

    International Nuclear Information System (INIS)

    Salerno, L.N.

    1985-01-01

    General Electric's long participation in liquid metal reactor technology has led to a Power Reactor Inherently Safe Module (PRISM) concept supported by DOE contract DE-AC06-85NE37937. The reactor module is sized to maximize inherent safety features. The small size allows factory fabrication, reducing field construction and field QA/QC labor, and allows safety to be demonstrated in full scale, to support a pre-licensed standard commercial product. The module is small enough to be placed underground, and can be combined with steam and electrical generating equipment to provide a complete electrical power producing plant in the range of 400-1200 MWe. Initial assessments are that the concept has the potential to be economically competitive with existing methods of power production used by the utility industry

  12. Keeping Sealed Radioactive Sources Safe and Secure

    International Nuclear Information System (INIS)

    Potterton, Louise

    2013-01-01

    Radioactive sources are used in a wide variety of devices in medical, industrial, agricultural and research facilities worldwide. These sources, such as cobalt-60 and caesium-137, emit high levels of ionizing radiation, which can treat cancer, measure materials used in industry and sterilize food and medical appliances. Problems may arise when these sources are no longer needed, or if they are damaged or decayed. If these sources are not properly stored they can be a threat to human health and the environment and pose a security risk. Procedures to secure these spent or 'disused' sources are often highly expensive and need specialized assistance. The IAEA helps its States find long term solutions for the safe and secure storage of disused sealed radioactive sources (DSRSs)

  13. Towards Safe Navigation by Formalizing Navigation Rules

    Directory of Open Access Journals (Sweden)

    Arne Kreutzmann

    2013-06-01

    Full Text Available One crucial aspect of safe navigation is to obey all navigation regulations applicable, in particular the collision regulations issued by the International Maritime Organization (IMO Colregs. Therefore, decision support systems for navigation need to respect Colregs and this feature should be verifiably correct. We tackle compliancy of navigation regulations from a perspective of software verification. One common approach is to use formal logic, but it requires to bridge a wide gap between navigation concepts and simple logic. We introduce a novel domain specification language based on a spatio-temporal logic that allows us to overcome this gap. We are able to capture complex navigation concepts in an easily comprehensible representation that can direcly be utilized by various bridge systems and that allows for software verification.

  14. Spark-safe mechanical fluctuation sensor

    Energy Technology Data Exchange (ETDEWEB)

    Retek, S; Galisz, T

    1979-04-20

    The subject of the invention is a mechanical fluctuation sensor in a spark-safe design for use at mines which are dangerous for gas, as an element of different systems for remote control information transfer. The patented sensor of mechanical fluctuations contains: magnetic-induction transformer characterized by the fact that its inert mass consists of a plane permanent magnet placed in the suspended state on springs between 2 coils, which together with their cores are rigidly fixed to the walls of the ferromagnetic vessels. The ends of the coil windings are interconnected, while the beginnings of the windings are lead out with connection to the outlet of the electronic amplifier with binary outlet signal. The electronic amplifier is placed between the transformer in the common ferromagnetic housing which is a screen for protection from the effect of external magnetic fields.

  15. Safe management of radioactive waste in Ghana

    International Nuclear Information System (INIS)

    Glover, E.T.; Fletcher, J.J.

    2000-01-01

    The Ghana Atomic Energy Commission was established in 1963 by an Act of Parliament, Act 204 for the Promotion, Development and Peaceful Application of Nuclear Techniques for the Benefit of Ghana. As in many developing countries the use of nuclear application is growing considerably in importance within the national economy. The Radiation Protection Board was established as the national regulatory authority and empowered by the Radiation Protection Instrument LI 1559 (1993). The above regulations, Act 204 and LI 1559 provided a minimum legal basis for regulatory control of radioactive waste management as it deals with waste management issues in a very general way and is of limited practical use to the waste producer. Hence the National Radioactive Waste Management Centre was established in July 1995 to carry out waste safety operations in Ghana. This paper highlights steps that have been taken to develop a systemic approach for the safe management of radioactive waste in the future and those already in existence. (author)

  16. Safe new reactor for radionuclide production

    International Nuclear Information System (INIS)

    Gray, P.L.

    1995-01-01

    In late 1995, DOE is schedule to announce a new tritium production unit. Near the end of the last NPR (New Production Reactors) program, work was directed towards eliminating risks in current designs and reducing effects of accidents. In the Heavy Water Reactor Program at Savannah River, the coolant was changed from heavy to light water. An alternative, passively safe concept uses a heavy-water-filled, zircaloy reactor calandria near the bottom of a swimming pool; the calandria is supported on a light-water-coolant inlet plenum and has upflow through assemblies in the calandria tubes. The reactor concept eliminates or reduces significantly most design basis and severe accidents that plague other deigns. The proven, current SRS tritium cycle remains intact; production within the US of medical isotopes such as Mo-99 would also be possible

  17. Safe Laser Beam Propagation for Interplanetary Links

    Science.gov (United States)

    Wilson, Keith E.

    2011-01-01

    Ground-to-space laser uplinks to Earth–orbiting satellites and deep space probes serve both as a beacon and an uplink command channel for deep space probes and Earth-orbiting satellites. An acquisition and tracking point design to support a high bandwidth downlink from a 20-cm optical terminal on an orbiting Mars spacecraft typically calls for 2.5 kW of 1030-nm uplink optical power in 40 micro-radians divergent beams.2 The NOHD (nominal ocular hazard distance) of the 1030nm uplink is in excess of 2E5 km, approximately half the distance to the moon. Recognizing the possible threat of high power laser uplinks to the flying public and to sensitive Earth-orbiting satellites, JPL developed a three-tiered system at its Optical Communications Telescope Laboratory (OCTL) to ensure safe laser beam propagation through navigational and near-Earth space.

  18. Microbes safely, effectively bioremediate oil field pits

    International Nuclear Information System (INIS)

    Shaw, B.; Block, C.S.; Mills, C.H.

    1995-01-01

    Natural and augmented bioremediation provides a safe, environmental, fast, and effective solution for removing hydrocarbon stains from soil. In 1992, Amoco sponsored a study with six bioremediation companies, which evaluated 14 different techniques. From this study, Amoco continued using Environmental Protection Co.'s (EPC) microbes for bioremediating more than 145 sites near Farmington, NM. EPC's microbes proved effective on various types of hydrocarbon molecules found in petroleum stained soils from heavy crude and paraffin to volatiles such as BTEX (benzene, toluene, ethylbenzene, xylene) compounds. Controlled laboratory tests have shown that these microbes can digest the hydrocarbon molecules with or without free oxygen present. It is believed that this adaptation gives these microbes their resilience. The paper describes the bioremediation process, environmental advantages, in situ and ex situ bioremediation, goals of bioremediation, temperature effects, time, cost, and example sites that were treated

  19. Safe and Secure Services Based on NGN

    Science.gov (United States)

    Fukazawa, Tomoo; Nisase, Takemi; Kawashima, Masahisa; Hariu, Takeo; Oshima, Yoshihito

    Next Generation Network (NGN), which has been undergoing standardization as it has developed, is expected to create new services that converge the fixed and mobile networks. This paper introduces the basic requirements for NGN in terms of security and explains the standardization activities, in particular, the requirements for the security function described in Y.2701 discussed in ITU-T SG-13. In addition to the basic NGN security function, requirements for NGN authentication are also described from three aspects: security, deployability, and service. As examples of authentication implementation, three profiles-namely, fixed, nomadic, and mobile-are defined in this paper. That is, the “fixed profile” is typically for fixed-line subscribers, the “nomadic profile” basically utilizes WiFi access points, and the “mobile profile” provides ideal NGN mobility for mobile subscribers. All three of these profiles satisfy the requirements from security aspects. The three profiles are compared from the viewpoint of requirements for deployability and service. After showing that none of the three profiles can fulfill all of the requirements, we propose that multiple profiles should be used by NGN providers. As service and application examples, two promising NGN applications are proposed. The first is a strong authentication mechanism that makes Web applications more safe and secure even against password theft. It is based on NGN ID federation function. The second provides an easy peer-to-peer broadband virtual private network service aimed at safe and secure communication for personal/SOHO (small office, home office) users, based on NGN SIP (session initiation protocol) session control.

  20. [Towards safe motherhood. World Health Day].

    Science.gov (United States)

    Plata, M I

    1998-06-01

    The objective of the 'safe motherhood' initiative is to reduce maternal mortality by 50% by the year 2000. A strong policy is needed to permit development of national and international programs. The lifetime risk of death from causes related to complications of pregnancy is estimated at 1/16 in Africa, 1/65 in Asia, 1/130 in Latin America and the Caribbean, 1/1400 in Europe, and 1/3700 in North America. A minimum of 585,000 women die of maternal causes each year, with nearly 90% of the deaths occurring in Asia and Africa. Approximately 50 million women suffer from illnesses related to childbearing. A principal cause of maternal mortality is lack of medical care during labor, delivery, and the postpartum period. Motherhood will become safe if governments, multilateral and bilateral funding agencies, and nongovernmental organizations give it the high priority it requires. Women also die because they lack rights. Their reduced decision-making power and inequitable access to family and social resources prevents them from overcoming barriers to health care. Women die when they begin childbearing at a very young age, yet an estimated 11% of births throughout the world each year are to adolescents. Adolescents have very limited access to family planning, either through legal restrictions or obstacles created by family planning workers. Maternal deaths would be avoided if all births were attended by trained health workers; an estimated 60 million births annually are not. Prevention of unwanted pregnancy and, thus, of the 50 million abortions estimated to take place each year would avoid over 200 maternal deaths each day. Unsafe abortions account for 13% of maternal deaths. The evidence demonstrates that rates of unsafe abortion and abortion mortality are higher where laws are more restrictive.

  1. Safe motherhood -- from advocacy to action.

    Science.gov (United States)

    Tinker, A

    1991-12-01

    Every minute a woman dies from complications related to pregnancy or childbirth. That translates to 500,000 annually, of which, 99% live in developing countries. A woman in Africa has a 1:18 lifetime chance of dying from pregnancy-related causes, compared with a northern European woman who has a 1:10,000 chance. Thus, in 1987 international and regional agencies and national governments started a global program titled the Safe Motherhood Initiative. Its goal is to reduce maternal morbidity and mortality 50% by 2000. The death of a woman during pregnancy or child birth means that her surviving children are much more likely to die. In a bangladesh study it was found that the death of the mother was associated with a 200% increase in mortality for her sons and 350% for her daughters for children up to 10. Family planning is the key, since it is the single best tool of preventing these deaths, by reducing the number of times a woman gets pregnant. Family planning also reduces the number of abortions which are estimated to kill 200,000 women annually in developing countries. Trained midwives who can provide obstetrical emergency assistance will also make a large impact. Risk assessment was once considered very important, but studies have shown that the majority of pregnancy complications develop without being detected. Further, the number of women with risk factors that develop complications is much lower than the number of women who develop complications during pregnancy. So monitoring women with risk factors misses most complications. Regular monitoring and medical examinations are much more effective for preventing complications. Safe motherhood can only be achieved if each program is tailored to the needs of the community. Donor nations are necessary for this program to succeed, but ultimate success rests in the hands of each country. National priorities must be set, resources must be allocated, and programs must be designed to be effective.

  2. 50 CFR 216.91 - Dolphin-safe labeling standards.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Dolphin-safe labeling standards. 216.91... MAMMALS Dolphin Safe Tuna Labeling § 216.91 Dolphin-safe labeling standards. (a) It is a violation of... include on the label of those products the term “dolphin-safe” or any other term or symbol that claims or...

  3. 25 CFR 700.55 - Decent, safe, and sanitary dwelling.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Decent, safe, and sanitary dwelling. 700.55 Section 700... PROCEDURES General Policies and Instructions Definitions § 700.55 Decent, safe, and sanitary dwelling. (a) General. The term decent, safe, and sanitary dwelling means a dwelling which— (1) Meets applicable federal...

  4. Decisions to regulate genotoxic substances

    Energy Technology Data Exchange (ETDEWEB)

    Bengtsson, G

    1988-07-01

    Decisions to regulate genotoxic substances involve trade-offs between various incomparable factors such as risks to human health and other environmental risks, public perceptions, costs and uncertainties. Two different approaches towards these trade-offs are discussed. In one approach, all relevant factors are defined and trade-offs are considered using a general and very elaborate analysis. Cost-benefit analysis is an exponent of this approach. An illustration is given for the regulation of transboundary releases of radioactive materials. The other approach considers what is politically feasible for the time being and seeks a decision with much room for later corrections. Incrementalism is a philosophy in this vein. It is illustrated by reference to the regulation of transboundary air pollution. Weaknesses and strengths of the two approaches are discussed. (author)

  5. Decisions to regulate genotoxic substances

    International Nuclear Information System (INIS)

    Bengtsson, G.

    1988-01-01

    Decisions to regulate genotoxic substances involve trade-offs between various incomparable factors such as risks to human health and other environmental risks, public perceptions, costs and uncertainties. Two different approaches towards these trade-offs are discussed. In one approach, all relevant factors are defined and trade-offs are considered using a general and very elaborate analysis. Cost-benefit analysis is an exponent of this approach. An illustration is given for the regulation of transboundary releases of radioactive materials. The other approach considers what is politically feasible for the time being and seeks a decision with much room for later corrections. Incrementalism is a philosophy in this vein. It is illustrated by reference to the regulation of transboundary air pollution. Weaknesses and strengths of the two approaches are discussed. (author)

  6. Organic substances of bituminous shales

    Energy Technology Data Exchange (ETDEWEB)

    Lanin, V A; Pronina, M V

    1944-01-01

    Samples of Gdov (Estonia) and Volga (Russia) oil shales were oxidized by alkaline permanganate to study the distribution of carbon and the composition of the resulting oxidation products. Gdov shale was rather stable to oxidation and, after 42 hours 61.2 percent of the organic material remained unoxidized. Five hundred hours were required for complete oxidation, and the oxidation products consisted of CO/sub 2/, acetic, oxalic, and succinic acids. The oxidation products from Volga shale consisted of CO/sub 2/, acetic, oxalic, succinic, adipic, phthalic, benzenetricarboxylic, benzenetetracarboxylic, and benzenepentacarboxylic acids. The results indicated that Gdov shale is free of humic substances and is of sapropelic origin, while Volga shale is of sapropelic-humic origin.

  7. Substance abuse precedes Internet addiction.

    Science.gov (United States)

    Lee, Young Sik; Han, Doug Hyun; Kim, Sun Mi; Renshaw, Perry F

    2013-04-01

    The purpose of the current study was to evaluate possible overlapping substance abuse and internet addiction in a large, uniformly sampled population, ranging in age from 13 to 18 years. Participants (N=73,238) in the current study were drawn from the 6th Korea Youth Risk Behavior Web-based Survey (KYRBWS-V) for students from 400 middle schools and 400 high schools in 16 cities within South Korea. Of adolescent internet users, 85.2% were general users (GU), 11.9% were users with potential risk for internet addiction (PR), and 3.0% were users with high risk for internet addiction (HR). There was a difference in the number of students with alcohol drinking among the GU, PR, and HR groups (20.8% vs 23.1% vs 27.4%). There was a difference in the number of students who smoked among the GS, PR, and HR groups (11.7% vs 13.5% vs 20.4%). There was a difference in the number of students with drug use among the GU, PR, and HR groups (1.7% vs 2.0% vs 6.5%). After adjusting for sex, age, stress, depressed mood, and suicidal ideation, smoking may predict a high risk for internet addiction (OR=1.203, p=0.004). In addition, drug use may predict a high risk for internet addiction (OR=2.591, paddiction have vulnerability for addictive behaviors, co-morbid substance abuse should be evaluated and, if found, treated in adolescents with internet addiction. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Peer Substance Use and Homelessness Predicting Substance Abuse from Adolescence Through Early Adulthood

    OpenAIRE

    Tompsett, Carolyn J.; Domoff, Sarah E.; Toro, Paul A.

    2013-01-01

    Adolescents who experience homelessness are at higher risk for abusing substances, and for being exposed to substance-using peers. The current study used a longitudinal design to track substance abuse, affiliation with substance-using peers, and episodes of homelessness among a sample of 223 adolescents who were homeless at thebaseline data collection and 148 adolescents who were housed at baseline. Participants were interviewed at six waves over 6.5 years, covering an age rang...

  9. 75 FR 1734 - Children’s Online Privacy Protection Rule Safe Harbor Proposed Self-Regulatory Guidelines; i-SAFE...

    Science.gov (United States)

    2010-01-13

    ... Proposed Self-Regulatory Guidelines; i-SAFE, Inc. Application for Safe Harbor AGENCY: Federal Trade... for public comment concerning proposed self-regulatory guidelines submitted by i-SAFE, Inc. under the... approval self-regulatory guidelines that would implement the Rule's protections.\\3\\ \\1\\ 64 FR 59888 (1999...

  10. Practical Reason, Another Approach of Safe Action

    International Nuclear Information System (INIS)

    Blazsin, H.; Guarnieri, F.; Martin, C.

    2016-01-01

    Born from the realisation that technology is neither the only source of risk, nor the exclusive solution, the concept of safety culture aimed at reintegrating human action, skills and symbolic productions (representations, beliefs, values, cognitive abilities, etc.) in the preservation of safety. As such it constituted a turning point for risk management and safety studies. Yet, the concept seems to raise more and more questions, both as a concept and as a practical tool (Simard, 2000; Fuchs, 2012; Edwards et al., 2013; Lopez de Castro et al., 2013). Mostly, these questions revolve around the lack of consensus over one shared definition of safety culture; around the idea that a number of its traditionally accepted characteristics, such as its systemic nature, remain to be demonstrated; finally, and maybe most importantly, that its implementation through such management tools as questionnaires, indicators, dashboards, has deprived safety culture of its substance and diverted from its original purpose, i.e., putting humanity back at the heart of safety (Guldenmund, 2007; Karsh, Waterson, Holden, 2013; Reiman, Rollenhagen, 2013). Indeed such tools lead to classify and quantify reality in an attempt at reproducibility, leaving aside the many aspects of human action that do not fit the associated categories as well as its complexity.

  11. Feeling safe during an inpatient hospitalization: a concept analysis.

    Science.gov (United States)

    Mollon, Deene

    2014-08-01

    This paper aims to explore the critical attributes of the concept feeling safe. The safe delivery of care is a high priority; however; it is not really known what it means to the patient to 'feel safe' during an inpatient hospitalization. This analysis explores the topic of safety from the patient's perspective. Concept analysis. The data bases of CINAHL, Medline, PsychInfo and Google Scholar for the years 1995-2012 were searched using the terms safe and feeling safe. The eight-step concept analysis method of Walker and Avant was used to analyse the concept of feeling safe. Uses and defining attributes, as well as identified antecedents, consequences and empirical referents, are presented. Case examples are provided to assist in the understanding of defining attributes. Feeling safe is defined as an emotional state where perceptions of care contribute to a sense of security and freedom from harm. Four attributes were identified: trust, cared for, presence and knowledge. Relationship, environment and suffering are the antecedents of feeling safe, while control, hope and relaxed or calm are the consequences. Empirical referents and early development of a theory of feeling safe are explored. This analysis begins the work of synthesizing qualitative research already completed around the concept of feeling safe by defining the key attributes of the concept. Support for the importance of developing patient-centred models of care and creating positive environments where patients receive high-quality care and feel safe is provided. © 2014 John Wiley & Sons Ltd.

  12. Teaching Resiliency Theory to Substance Abuse Counselors

    Science.gov (United States)

    Ward, Kelly

    2003-01-01

    Resiliency is the ability to cope in the face of adversity. One protective factor that promotes resiliency in substance-abusing dysfunctional families is family rituals and traditions. Social workers and substance abuse counselors can teach family members how to instill resiliency in their families and themselves through rituals and traditions. To…

  13. Substance Abuse and the American Woman.

    Science.gov (United States)

    Columbia Univ., New York, NY. National Center on Addiction and Substance Abuse.

    The first comprehensive assessment of substance abuse and women, this report arose from an analysis of more than 1,700 scientific and technical articles, surveys, government reports and books. Results show that American women are closing the gap with men in that they are increasingly likely to abuse substances at the same rate as men. Findings…

  14. National Toxic Substance Incidents Program (NTSIP)

    Centers for Disease Control (CDC) Podcasts

    2011-02-03

    This podcast gives an overview of the three components of the National Toxic Substance Incidents Program: state surveillance, national database, and response teams.  Created: 2/3/2011 by Agency for Toxic Substances and Disease Registry.   Date Released: 2/3/2011.

  15. Factors Influencing Substance Abuse among Undergraduate ...

    African Journals Online (AJOL)

    The study investigated the factors influencing substance abuse amongundergraduate students in Osun State; Nigeria. A sample of 1, 200undergraduate students were randomly selected from three tertiaryinstitution in Osun State. Factors Influencing Substance Abuse Questionnaire (FISA) was developed by the researcher ...

  16. Determinants of psychoactive substance use among incarcerated ...

    African Journals Online (AJOL)

    The average age of first use was 12.6 ± 5.9 years. The prevalence of lifetime and current use of any substance was 88.0% and 64.3% respectively. Prior arrest, being sexually active and family drug use significantly (p<0.05) predicted lifetime use of any substance while being raised in a monogamous family was protective.

  17. CHANGES IN STRUCTURE AND CONTENT HUMIC SUBSTANCES

    Directory of Open Access Journals (Sweden)

    Maroš SIROTIAK

    2016-06-01

    Full Text Available The paper deals with the process of thermal degradation of humic substances in soil samples exposed to increased temperature. To determine the basic properties of humic substances, humic and fulvic acids are used conventional fractionation chemical laboratory methods. To determine changes in the chemical structure, the method of use of FT-IR ATR spectroscopy technique.

  18. Contextual Factors in Adolescent Substance Use.

    Science.gov (United States)

    Hochhauser, Mark; And Others

    Research on adolescent substance use has focused on prevalence and incidence; however, contextual factors have been largely ignored. A survey of 155 adolescents from a Minneapolis suburb was conducted to assess contextual factors affecting adolescent substance use. Subjects reported their use of alcohol, cigarettes, and marihuana with respect to…

  19. Perceptions of Elders' Substance Abuse and Resilience

    Science.gov (United States)

    Kane, Michael N.; Green, Diane

    2009-01-01

    Human service students' (social work, criminal justice, public administration, psychology) were surveyed (N = 242). Their perceptions about older persons' resilience and recovery from substance abuse were investigated. Overall, respondents did not agree that treating older persons for a substance abuse problem was wasteful of resources or older…

  20. Moving On: Young People and Substance Abuse

    Science.gov (United States)

    Daley, Kathryn; Chamberlain, Chris

    2009-01-01

    To help explain why some young people move from recreational drug use to substance abuse, twelve in-depth interviews were conducted with young people who had experienced problematic substance use. The data were supplemented by statistical data on 111 young people. The researchers found a variety of "structural" factors that help explain…

  1. Perception of Nigerian healthcare professionals about substance ...

    African Journals Online (AJOL)

    Results: Excess workload/stress of work was perceived as the most common reason for abusing drugs. Overall, substance abuse was perceived as a mental health problem. However, those that abuse substances more readily perceived it as a habit problem rather than a mental health challenge. Moreover, there was lower ...

  2. Physical harm due to chronic substance use

    NARCIS (Netherlands)

    van Amsterdam, Jan; Pennings, Ed; Brunt, Tibor; van den Brink, Wim

    2013-01-01

    Chronic use at high dose of illicit drugs, alcohol and tobacco is associated with physical disease. The relative physical harm of these substances has not been described before, but will benefit the guiding of policy measures about licit and illicit substances. The physical harm of 19 addictive

  3. Safe affordable fission engine (SAFE 30) module conductivity test thermal model correlation

    International Nuclear Information System (INIS)

    Roman, Jose

    2001-01-01

    The SAFE 30 is a simple, robust space fission power system that is comprised of several independent modules. Each module contains 4 fuel tubes bonded to a central heatpipe. Fission energy is conducted from the fuel tubes to the heatpipe, which in turn transfers the energy to a power conversion system. This paper benchmarks a thermal model of the SAFE 30 with actual test data from simulated SAFE 30 module tests. Two 'dummy' SAFE 30 modules were fabricated - each consisted of 4 1-inch dia. tubes (simulating the fuel tubes) bonded to a central '1' dia. tube (simulating the heatpipe). In the first module the fuel tubes were simply brazed to the heatpipe along the line of contact (leaving void space in the interstices), and in the second module the tubes and heatpipe were brazed via tri-cusps that completely fill the interstices between the tubes. In these tests, fission energy is simulated by placing resistance heaters within each of the 4 fuel tubes. The tests were conducted in a vacuum chamber in 4 configurations: tri-cusps filled with and without an outer insulation wrap, and no tri-cusps with and without an outer insulation wrap. The baseline SAFE 30 configuration uses the brazed tri-cusps. During the tests, the power applied to the heaters was varied in a stepwise fashion, until a steady-state temperature profile was reached. These temperature levels varied between 773 K and 1073 K. To benchmark the thermal model, the input energy and chamber surface temperature were used as boundary conditions for the model. The analytical results from the nodes at the same location as the test thermocouples were plotted again test data to determinate the accuracy of the analysis. The unknown variables on the analysis are the radiation emissivity of the pipe and chamber and the radiation view factor between the module and the chamber. A correlation was determined using a parametric analysis by varying the surface emissivity and view factor until a good match was reached. This

  4. Substance abuse: medical and slang terminology.

    Science.gov (United States)

    Hamid, Humera; El-Mallakh, Rif S; Vandeveir, Keith

    2005-03-01

    Substance abuse is among one of the major problems plaguing our society. It has come to the attention of several healthcare professionals that a communication gap exists between themselves and substance abusers. Most of the time the substance abusers are only familiar with the slang terms of abused substances, a terminology that medical professionals are usually unaware of. This paper is an attempt to close that communication gap, allowing health care professionals to understand the slang terminology that their patients use, thus enabling them to make appropriate treatment decisions. In addition, the article presents some key features (including active ingredient, pharmacological classification, medical use, abuse form, usage method, combinations used, effects sought, long-term possible effects, and detectability in urine) of the most commonly abused substances.

  5. Conceptual design of inherently safe integral reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. I.; Chang, M. H.; Lee, D. J. and others

    1999-03-01

    The design concept of a 300 MWt inherently safe integral reactor(ISIR) for the propulsion of extra large and superhigh speed container ship was developed in this report. The scope and contents of this report are as follows : 1. The state of the art of the technology for ship-mounted reactor 2. Design requirements for ISIR 3. Fuel and core design 4. Conceptual design of fluid system 5. Conceptual design of reactor vessel assembly and primary components 6. Performance analyses and safety analyses. Installation of two ISIRs with total thermal power of 600MWt and efficiency of 21% is capable of generating shaft power of 126,000kW which is sufficient to power a container ship of 8,000TEU with 30knot cruise speed. Larger and speedier ship can be considered by installing 4 ISIRs. Even though the ISIR was developed for ship propulsion, it can be used also for a multi-purpose nuclear power plant for electricity generation, local heating, or seawater desalination by mounting on a movable floating barge. (author)

  6. Safe Handling of Radioisotopes. Health Physics Addendum

    International Nuclear Information System (INIS)

    Appleton, G.J.; Krishnamoorthy, P.N.

    1960-01-01

    The International Atomic Energy Agency published in 1958 a Manual entitled ''Safe Handling of Radioisotopes'' (Safety Series No. 1 - STI/PUB/1), based on the work of an international panel convened by the Agency. As recommended by that panel and approved by the Agency's Board of Governors, this Addendum has now been prepared, primarily as a supplement to the Manual. It contains technical information necessary for the implementation of the controls given in the Manual. In addition, it is intended to serve as a brief introduction to the technical problems encountered in radiological protection work and to the methods of resolving them. As in the case of the Manual itself, the information given in this Addendum is particularly relevant to the problems encountered by the small user of radioisotopes. Although the basic principles set forth in it apply to all work with radiation sources, the Addendum is not intended to serve as a radiological protection manual for use in reactor installations or large-scale nuclear industry, where more specialized techniques and information are required.

  7. SGLT2 inhibitors: are they safe?

    Science.gov (United States)

    Filippas-Ntekouan, Sebastian; Filippatos, Theodosios D; Elisaf, Moses S

    2018-01-01

    Sodium-glucose linked transporter type 2 (SGLT2) inhibitors are a relatively new class of antidiabetic drugs with positive cardiovascular and kidney effects. The aim of this review is to present the safety issues associated with SGLT2 inhibitors. Urogenital infections are the most frequently encountered adverse events, although tend to be mild to moderate and are easily manageable with standard treatment. Although no increased acute kidney injury risk was evident in the major trials, the mechanism of action of these drugs requires caution when they are administered in patients with extracellular volume depletion or with drugs affecting renal hemodynamics. Canagliflozin raised the risk of amputations and the rate of fractures in the CANVAS trial, although more data are necessary before drawing definite conclusions. The risk of euglycemic diabetic ketoacidosis seems to be minimal when the drugs are prescribed properly. Regarding other adverse events, SGLT2 inhibitors do not increase the risk of hypoglycemia even when co-administered with insulin, but a decrease in the dose of sulphonylureas may be needed. The available data do not point to a causative role of SGLT2 inhibitors on malignancy risk, however, these drugs should be used with caution in patients with known hematuria or history of bladder cancer. SGLT2 inhibitors seem to be safe and effective in the treatment of diabetes but more studies are required to assess their long-term safety.

  8. How to Observe the Sun Safely

    CERN Document Server

    Macdonald, Lee

    2012-01-01

    How to Observe the Sun Safely, Second Edition gives all the basic information and advice the amateur astronomer needs to get started in observing our own ever-fascinating star. Unlike many other astronomical objects, you do not need a large telescope or expensive equipment to observe the Sun. And it is possible to take excellent pictures of the Sun with today's low-cost digital cameras! This book surveys what is visible on the Sun and then describes how to record solar features and measure solar activity levels. There is also an account of how to use H-alpha and Calcium-K filters to observe and record prominences and other features of the solar chromosphere, the Sun's inner atmosphere. Because we are just entering a period of high activity on the Sun, following a long, quiet period, this is a great time to get involved with solar observing. Still emphasizing safety first, this Second Edition reflects recent and exciting advances in solar observing equipment. Chapters 6 through 8 have been completely revised ...

  9. Safe Handling of Radioisotopes. Health Physics Addendum

    Energy Technology Data Exchange (ETDEWEB)

    Appleton, G J; Krishnamoorthy, P N

    1960-07-15

    The International Atomic Energy Agency published in 1958 a Manual entitled ''Safe Handling of Radioisotopes'' (Safety Series No. 1 - STI/PUB/1), based on the work of an international panel convened by the Agency. As recommended by that panel and approved by the Agency's Board of Governors, this Addendum has now been prepared, primarily as a supplement to the Manual. It contains technical information necessary for the implementation of the controls given in the Manual. In addition, it is intended to serve as a brief introduction to the technical problems encountered in radiological protection work and to the methods of resolving them. As in the case of the Manual itself, the information given in this Addendum is particularly relevant to the problems encountered by the small user of radioisotopes. Although the basic principles set forth in it apply to all work with radiation sources, the Addendum is not intended to serve as a radiological protection manual for use in reactor installations or large-scale nuclear industry, where more specialized techniques and information are required.

  10. Safe design of protective structures of tunnels

    International Nuclear Information System (INIS)

    Farahat, M.A.Z.

    2011-01-01

    This research aims to explain how to use a tunnel, constructed from reinforced concrete, passes under a river to protect some people. The computer code is used (MCNP) (the transfer photon and neutron) at this model for such tunnel which passes under a river to account attenuation of both neutrons and gamma rays passing through the river water, clay, soil and reinforced concrete wall layers ,the last one (thickness 40 cm)constructed the tunnel construction. And to account the dose inside the tunnel, and to account neutron dose, gamma dose, prompt gamma dose, total gamma dose and total (neutron + gamma) dose estimated by μSv/h. At different depths from the earth surface layer depths 100 cm, 250 cm, 500 cm, 750 cm , 1000 cm, 1300 cm, 1700 cm, 1900 cm, 2020 cm, 2500 cm). And then account these doses for three cases which are a nuclear bomb its intensity 20 kt, another bomb its intensity 100 kt, and the last one its intensity is 1000 kt. This research aims to account the required safe depth to protect some people in this tunnel, passing under a river from the dangerous effects of neutron and gamma rays, emitted from the nuclear bomb.

  11. Is percutaneous nephrolithotomy in solitary kidneys safe?

    Science.gov (United States)

    Wong, Kathie Alexina; Sahai, Arun; Patel, Amit; Thomas, Kay; Bultitude, Matthew; Glass, Jonathan

    2013-11-01

    To review our experience from a high volume stone center with a focus on efficacy, safety, and renal function. Stones requiring percutaneous nephrolithotomy (PCNL) in patients with solitary kidneys can pose significant anxiety to the urologist. Limited data are available in published reports in this setting. A comprehensive retrospective review of medical records was performed on patients who underwent PCNL and had a solitary kidney or a single functioning renal unit. Data were collected on patient demographics, stone burden, outcomes, complications, and renal function. Of 378 PCNLs performed between January 2003 and September 2011, 22 were performed in 17 patients with a single functioning kidney. Three procedures were performed in a transplanted kidney. In those with solitary calculus, the longest mean length and stone surface area were 37 mm and 825 mm(2), respectively. Stone-free rate was 59%. Auxiliary procedures were required in 6 cases, resulting in a stone-free rate of 77%. Median inpatient stay was 4 days. Serum creatinine values improved from 144 to 126 umol/L before and after the procedure and mean estimated glomerular filtration rate improved similarly from 51 to 59 mls/minute, respectively. Blood transfusion was required in 1 patient, sepsis developed in 3, and 2 patients required a stent for obstruction. PCNL in solitary kidneys is safe with an acceptable complication rate if performed in a high volume center. Outcomes are good, although auxiliary procedures may be necessary. Renal function remains stable or improves after procedure. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. IRCAD recommendation on safe laparoscopic cholecystectomy.

    Science.gov (United States)

    Conrad, Claudius; Wakabayashi, Go; Asbun, Horacio J; Dallemagne, Bernard; Demartines, Nicolas; Diana, Michele; Fuks, David; Giménez, Mariano Eduardo; Goumard, Claire; Kaneko, Hironori; Memeo, Riccardo; Resende, Alexandre; Scatton, Olivier; Schneck, Anne-Sophie; Soubrane, Olivier; Tanabe, Minoru; van den Bos, Jacqueline; Weiss, Helmut; Yamamoto, Masakazu; Marescaux, Jacques; Pessaux, Patrick

    2017-11-01

    An expert recommendation conference was conducted to identify factors associated with adverse events during laparoscopic cholecystectomy (LC) with the goal of deriving expert recommendations for the reduction of biliary and vascular injury. Nineteen hepato-pancreato-biliary (HPB) surgeons from high-volume surgery centers in six countries comprised the Research Institute Against Cancer of the Digestive System (IRCAD) Recommendations Group. Systematic search of PubMed, Cochrane, and Embase was conducted. Using nominal group technique, structured group meetings were held to identify key items for safer LC. Consensus was achieved when 80% of respondents ranked an item as 1 or 2 (Likert scale 1-4). Seventy-one IRCAD HPB course participants assessed the expert recommendations which were compared to responses of 37 general surgery course participants. The IRCAD recommendations were structured in seven statements. The key topics included exposure of the operative field, appropriate use of energy device and establishment of the critical view of safety (CVS), systematic preoperative imaging, cholangiogram and alternative techniques, role of partial and dome-down (fundus-first) cholecystectomy. Highest consensus was achieved on the importance of the CVS as well as dome-down technique and partial cholecystectomy as alternative techniques. The put forward IRCAD recommendations may help to promote safe surgical practice of LC and initiate specific training to avoid adverse events. © 2017 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

  13. Safe transport of radioactive material. Second edition

    International Nuclear Information System (INIS)

    1996-01-01

    In 1991, the International Atomic Energy Agency published Training Course Series No. 1 (TCS-1), a training manual that provides in 20 chapters a detailed discussion of the background, philosophy, technical bases and requirements and implementation aspects of the Regulations for the Safe Transport of Radioactive Material. The Transport Regulations are widely implemented by the IAEA's Member States and are also used as the bases for radioactive material transport requirements of modal organisations such as the International Maritime Organization and the International Civil Aviation Organization. This document is a supplement of TCS-1 to provide additional material in the form of learning aids and new exercises, that have been developed with the use of TCS-1 at succeeding IAEA training courses. The learning aids in the first part of the supplement are hitherto unpublished material that provide detailed guidance useful in solving the exercises presented in the second part. Solutions to the exercises are on field at the IAEA Secretariat and are available by arrangement to lectures presenting IAEA training courses. 4 refs, 1 fig., 6 tabs

  14. Bike to work safely (follow-up)

    CERN Document Server

    Simon Baird, HSE Unit Head

    2016-01-01

    Following a recent article about safe cycling (see here), the Bulletin received a request for more details on the type of accidents that are reported.   An analysis of the 38 accidents involving bicycles reported this year up to the end of August reveals that the most common single cause of accidents is slippery surfaces: ice, snow, water and gravel, so the message here is to take extra care, particularly when cycling in bad weather. The second item on the list is obstacles of various kinds: collisions with kerbs, potholes and even the transition from roads to cycle paths. The lesson here is to pay close attention to the surface you’re cycling over, and if you do spot a pothole, even if it does not lead to an accident, report it so that it can be repaired. It’s also worth remembering that you’re more likely to avoid coming off your bike if you keep your hands on the handlebars. The third highest cause is collisions with other vehicles, and here there are lessons for ...

  15. Distributed Programming via Safe Closure Passing

    Directory of Open Access Journals (Sweden)

    Philipp Haller

    2016-02-01

    Full Text Available Programming systems incorporating aspects of functional programming, e.g., higher-order functions, are becoming increasingly popular for large-scale distributed programming. New frameworks such as Apache Spark leverage functional techniques to provide high-level, declarative APIs for in-memory data analytics, often outperforming traditional "big data" frameworks like Hadoop MapReduce. However, widely-used programming models remain rather ad-hoc; aspects such as implementation trade-offs, static typing, and semantics are not yet well-understood. We present a new asynchronous programming model that has at its core several principles facilitating functional processing of distributed data. The emphasis of our model is on simplicity, performance, and expressiveness. The primary means of communication is by passing functions (closures to distributed, immutable data. To ensure safe and efficient distribution of closures, our model leverages both syntactic and type-based restrictions. We report on a prototype implementation in Scala. Finally, we present preliminary experimental results evaluating the performance impact of a static, type-based optimization of serialization.

  16. Can the Ignalina NPP be safe?

    International Nuclear Information System (INIS)

    Kutas, S.

    1999-01-01

    Many countries started using nuclear power before Lithuania, the IAEA and NEA were established and have been functioning efficiently, numerous conventions have been signed that control nuclear activities, nuclear safety regulations and standards have been set. Lithuania which is striving to integrate into the West European structures and to become a member of the 'club' of the world's nuclear states, has become a full and equal member of the IAEA and recognises its recommendations. Furthermore, it has signed or joined international conventions and is doing its best to introduce the practice of controlling nuclear safety applied in western countries. Nuclear safety cannot be taken as something finite that does not change. The requirements of nuclear and radiation safety are continuously redefined taking into consideration scientific discoveries and inventions as well as technical progress. Safety assurance can be the only criterion that should determine whether the nuclear power plant can be operated in Lithuania. The safety analysis report confirmed that the Ignalina NPP can be safely operated until the channel-graphite gap closes. The experiments conducted to date have convincingly shown that by the year 2000 the gap will not close in any of the fuel channels of unit 1. It can be hoped that the submitted studies, analyses and assessments will confirm that the Ignalina NPP meets Lithuania's nuclear safety requirements that have been drawn up in compliance with the recommendations of IAEA

  17. Safe Handling of Radioisotopes. Medical Addendum

    International Nuclear Information System (INIS)

    Hercik, F.; Jammet, H.

    1960-01-01

    The International Atomic Energy Agency published in 1958 a Manual entitled ''Safe Handling of Radioisotopes'' (Safety Series No. 1 - STI/PUB/1), based on the work of an international panel convened by the Agency. As recommended by that panel and approved by the Agency's Board of Governors, this Addendum has now been prepared, primarily as a supplement to the Manual. It contains information necessary to medical officers concerned with the implementation of the controls given in the Manual. In addition, it is intended to serve as a brief introduction to the medical problems encountered in radiological protection work and to the methods of resolving them. As in the case of the Manual itself, the information given in this Addendum is particularly relevant to the problems encountered by the small user of radioisotopes. Although the basic principles set forth in it apply to all work with radiation sources, the Addendum is not intended to serve as a radiological protection manual for use in reactor installations or large-scale nuclear industry, where more specialized techniques and information are required.

  18. CarbonSAFE Illinois - Macon County

    Energy Technology Data Exchange (ETDEWEB)

    Whittaker, Steve [University of Illinois; Illinois State Geological Survey

    2017-08-03

    CarbonSAFE Illinois is a a Feasibility study to develop an established geologic storage complex in Macon County, Illinois, for commercial-scale storage of industrially sourced CO2. Feasibility activities are focused on the Mt. Simon Storage Complex; a step-out well will be drilled near existing storage sites (i.e., the Midwest Geological Sequestration Consortium’s Illinois Basin – Decatur Project and the Illinois Industrial Carbon Capture and Storage Project) to further establish commercial viability of this complex and to evaluate EOR potential in a co-located oil-field trend. The Archer Daniels Midland facility (ethanol plant), City Water, Light, and Power in Springfield, Illinois (coal-fired power station), and other regional industries are potential sources of anthropogenic CO2 for storage at this complex. Site feasibility will be evaluated through drilling results, static and dynamic modeling, and quantitative risk assessment. Both studies will entail stakeholder engagement, consideration of infrastructure requirements, existing policy, and business models. Project data will help calibrate the National Risk Assessment Partnership (NRAP) Toolkit to better understand the risks of commercial-scale carbon storage.

  19. Ultra Safe And Secure Blasting System

    Energy Technology Data Exchange (ETDEWEB)

    Hart, M M

    2009-07-27

    The Ultra is a blasting system that is designed for special applications where the risk and consequences of unauthorized demolition or blasting are so great that the use of an extraordinarily safe and secure blasting system is justified. Such a blasting system would be connected and logically welded together through digital code-linking as part of the blasting system set-up and initialization process. The Ultra's security is so robust that it will defeat the people who designed and built the components in any attempt at unauthorized detonation. Anyone attempting to gain unauthorized control of the system by substituting components or tapping into communications lines will be thwarted in their inability to provide encrypted authentication. Authentication occurs through the use of codes that are generated by the system during initialization code-linking and the codes remain unknown to anyone, including the authorized operator. Once code-linked, a closed system has been created. The system requires all components connected as they were during initialization as well as a unique code entered by the operator for function and blasting.

  20. Evaluation of efalizumab using safe psoriasis control

    Directory of Open Access Journals (Sweden)

    Henninger Eric

    2006-09-01

    Full Text Available Abstract Background Safe Psoriasis Control (SPC is an important comprehensive measure that is validated for the assessment of benefit:risk of psoriasis treatments, combining efficacy, quality of life, and safety measures. The objective of this analysis was to assess the benefit:risk of efalizumab, a novel biologic agent indicated for the treatment of moderate-to-severe plaque psoriasis, by applying the SPC to data from randomized, placebo-controlled clinical studies of efalizumab. Methods SPC was applied to week 12 data from four placebo-controlled, Phase III studies: three retrospective and one prospective, the latter including a cohort of "high-need" patients for whom existing therapies were inadequate or unsuitable. Results In the retrospective analysis, 39.4% of patients achieved SPC after 12 weeks of treatment with efalizumab, compared with 10.4% for placebo. In the prospective analysis, 34.3% of patients achieved SPC after 12 weeks of treatment with efalizumab, compared with 7.3% on placebo. Among high-need patients, 33.0% achieved SPC, compared with 3.4% on placebo. Conclusion Efalizumab has a favorable benefit:risk profile using the comprehensive outcome measure SPC.

  1. Safe Care to Knee Injuries in Athletes

    Directory of Open Access Journals (Sweden)

    Gerardo Águila Tejeda

    2013-04-01

    Full Text Available Background: the guarantee of sporting success lies in the appropriate functioning of the musculoskeletal system, given that its vulnerability hinders the performance of each athlete. Being timely is critical to provide safe care to the affections of knee; late diagnosis in this system may lead to the development of complications and hinder sport practice. Objective: to characterize knee injuries in athletes of the sport system in the province of Cienfuegos.Methods: an observational, quantitative and qualitative, longitudinal and retrospective study was conducted. It included 104 athletes who attended the Traumatology Consultation from 2009 to 2011, presenting different types of knee injuries in various stages of training. Variables such as age, sex, sport, site of injury, stage of training, kilocalories consumed, type of training, quality of equipment and diagnosis were analyzed. The procedure used consists of a comprehensive review of case notes and medical records of all patients that attended consultation during the period analyzed, from which the necessary data was collected. Interviews with coaches and technical staff were carried out as well. Results: knee injuries occur in all ages of athletes, with a slight predominance of males. Highest frequencies are those of the ligament and meniscus, with the highest incidence in athletics, volleyball and judo. Conservative treatment predominated.Conclusions: knee injuries require a timely treatment in order to achieve athlete's success and safety.

  2. Safe nuclear power for the Third World

    International Nuclear Information System (INIS)

    Johnson, W.R.; Lyon, C.F.; Redick, J.R.

    1989-01-01

    It is clear that using nuclear power for the generation of electricity is one way of reducing the emissions of CO 2 and other gases that contribute to the greenhouse effect. Equally clear is the fact that the reduction can be magnified by converting domestic, commercial, and industrial power-consuming activities from the direct use of fossil fuel sources to electrical energy. A major area for future progress in limiting CO 2 emissions is in the Third World, where population growth and expectations for a higher social and economic standard of living portend vast increases in future energy use. A number of problems come to mind as one contemplates the widespread expansion of nuclear energy use into the Third World. The authors propose a method involving the marriage of two currently evolving concepts by which nuclear electrical generation can be expanded throughout the world in a manner that will address these problems. The idea is to form multinational independent electric generating companies, or nuclear electric companies (NECs), that would design, build, operate, and service a standardized fleet of nuclear power plants. The plants would be of the Integral Fast Reactor (IFR) design, now under development at Argonne National Laboratory, and, in particular, a commercial conceptualization of the IFR sponsored by General Electric Company, the Power Reactor Inherently Safe Module (PRISM)

  3. The safe transport of radioactive materials

    International Nuclear Information System (INIS)

    Swindell, G.E.

    1975-01-01

    In the course of transport by road, rail, sea and air, consignments of radioactive material are in close proximity to ordinary members of the public and in most cases they are loaded and unloaded by transport workers who have no special training or experience in the handling of radioactive substances. The materials being transported cover a wide variety - ranging from small batches of short-lived radionuclides used in medical practice which can be transported in small sealed lead pots in cardboard boxes, to large, extremely radioactive consignments of irradiated nuclear fuel in flasks weighing many tons. With the growing development of nuclear power programmes the transport of irradiated fuel is likely to increase markedly. It is clear that unless adequate regulations concerning the design and assembly of the packages containing these materials are precisely set down and strictly carried out, there would be a high probability that some of the radioactive contents would be released, leading to contamination of other transported goods and the general environment, and to the delivery of a radiation dose to the transport workers and the public. An additional requirement is that the transport should proceed smoothly and without delay. This is particularly important for radioactive materials of short half-life, which would lose significant amounts of their total activity in unnecessary delays at international boundaries. Therefore, it is essential that the regulations are also enforced, to ensure that the radioactive material is contained and the surrounding radiation level reduced to a value which poses no threat to other sensitive goods such as photographic film, or to transport workers and other passengers. These regulations should be as uniform as possible on an international basis, so that consignments can move freely from one country to another with as little delay as possible at the frontiers. (author)

  4. USING THE SAFE SYSTEM APPROACH TO KEEP OLDER DRIVERS SAFELY MOBILE

    Directory of Open Access Journals (Sweden)

    Jim LANGFORD

    2006-01-01

    Full Text Available In 2003, Australian road transport jurisdictions collectively accepted that the greatest road safety gains would be achieved through adopting a Safe System approach, derived from Sweden's Vision Zero and the Netherlands' Sustainable Safety strategies. A key objective of all three approaches is to manage vehicles, the road infrastructure, speeds, road users and the interactions between these components, to ensure that in the event of crashes, crash energies will remain at levels that minimize the probability of death and serious injury. Older drivers pose a particular challenge to the Safe System approach, given particularly their greater physical frailty, their driving patterns and for some at least, their reduced fitness to drive. This paper has analyzed the so-called ‘older driver problem’ and identified a number of key factors underpinning their crash levels, for which countermeasures can be identified and implemented within a Safe System framework. The recommended countermeasures consist of: (1 safer roads, through a series of design improvements particularly governing urban intersections; (2 safer vehicles, through both the promotion of crashworthiness as a critical consideration when purchasing a vehicle and the wide use of developed and developing ITS technologies; (3 safer speeds especially at intersections; and (4 safer road users, through both improved assessment procedures to identify the minority of older drivers with reduced fitness to drive and educational efforts to encourage safer driving habits particularly but not only through self-regulation.

  5. MR-guided preoperative localization and percutaneous core biopsy of suspicious breast lesions - experience on the vertically open 0.5 T system

    International Nuclear Information System (INIS)

    Schneider, J.P.; Schulz, T.; Rueger, S.; Schmidt, F.; Kahn, T.; Leinung, S.; Briest, S.

    2002-01-01

    Purpose. To evaluate the feasibility of performing breast interventions in a vertically open 0.5 T MR system (SIGNA SP/i, GE Medical Systems). To develop fitted equipment and to establish preoperative wire localization and percutaneous breast core biopsy as clinical routine procedures. Patients and methods. Initially, we applied a localization method with the patient placed in a sitting position in 31 cases using a single loop coil and a self-developed fixation device. Subsequently, 46 wire localizations and 28 percutaneous core biopsies were carried out in prone patient position using an open breast coil with an integrated biopsy device. The used instruments were either MR-compatible (18 G biopsy needle and localization wire, 14 G coaxial needle, prototype of a 16 G double-shoot gun) or MR-safe (double-shoot gun with 16 G needle). Results. After biopsy we found the needle tip (18 G for a wire localization and 14 G for a percutaneous core biopsy, respectively) placed either within or close to the lesions ( [de

  6. Flask for highly radioactive substances

    International Nuclear Information System (INIS)

    1980-01-01

    The flask for highly radioactive substances described in this invention comprises a thick steel cylinder with leak proof closures at both ends and made up of several coaxial rings in rolled sheet steel, fitted into each other and welded to each other along their edges. The inner ring is preferably in sheet steel with a lining on its internal side, for instance a stainless steel lining. Likewise the outer ring is preferably in sheet steel with a covering on its outer side. The cylindrical body of the flask is welded by its lower end to a forged steel bottom and by its upper end to a forged steel ring. The bottom can also be made with several partitions. This forged steel ring has an inside peripheral shoulder and the upper end of the flask is closed in a leak proof manner by an initial forged steel plus resting on this shoulder and bolted to it and by a second plug bolted to the free end of this ring [fr

  7. Safe Management Of Fast Reactors: Towards Sustainability

    International Nuclear Information System (INIS)

    Dreimanis, Andrejs

    2015-01-01

    An interdisciplinary systemic approach to socio-technical optimization of nuclear energy management is proposed, by recognizing a) the rising requirements to nuclear safety being realized using fast reactors (FR), b) the actuality to maintain and educate qualified workforce for fast reactors, c) the reactor safety and public awareness as the keystones for improving attitude to implement novel reactors. Knowledge management and informational support firstly is needed in: 1) technical issues: a) nuclear energy safety and reliability, b) to develop safe and economic technologies; 2) societal issues: a) general nuclear awareness, b) personnel education and training, c) reliable staff renascence, public education, stakeholder involvement, e).risk management. The key methodology - the principles being capable to manage knowledge and information issues: 1) a self-organization concept, 2) the principle of the requisite variety. As a primary source of growth of internal variety is considered information and knowledge. Following questions are analyzed indicating the ways of further development: a) threats in peaceful use of nuclear energy, b) basic features of nuclear risks, including terrorism, c) human resource development: basic tasks and instruments, d) safety improvements in technologies, e) advanced research and nuclear awareness improvement There is shown: public education, social learning and the use of mass media are efficient mechanisms forming a knowledge-creating community thereby reasoning to facilitate solution of key socio-technical nuclear issues: a) public acceptance of novel nuclear objects, b) promotion of adequate risk perception, and c) elevation of nuclear safety level and adequate risk management resulting in energetic and ecological sustainability. (author)

  8. Ultrasonic Detectors Safely Identify Dangerous, Costly Leaks

    Science.gov (United States)

    2013-01-01

    In 1990, NASA grounded its space shuttle fleet. The reason: leaks detected in the hydrogen fuel systems of the Space Shuttles Atlantis and Columbia. Unless the sources of the leaks could be identified and fixed, the shuttles would not be safe to fly. To help locate the existing leaks and check for others, Kennedy Space Center engineers used portable ultrasonic detectors to scan the fuel systems. As a gas or liquid escapes from a leak, the resulting turbulence creates ultrasonic noise, explains Gary Mohr, president of Elmsford, New York-based UE Systems Inc., a long-time leader in ultrasonic detector technologies. "In lay terms, the leak is like a dog whistle, and the detector is like the dog ear." Because the ultrasound emissions from a leak are highly localized, they can be used not only to identify the presence of a leak but also to help pinpoint a leak s location. The NASA engineers employed UE s detectors to examine the shuttle fuel tanks and solid rocket boosters, but encountered difficulty with the devices limited range-certain areas of the shuttle proved difficult or unsafe to scan up close. To remedy the problem, the engineers created a long-range attachment for the detectors, similar to "a zoom lens on a camera," Mohr says. "If you are on the ground, and the leak is 50 feet away, the detector would now give you the same impression as if you were only 25 feet away." The enhancement also had the effect of reducing background noise, allowing for a clearer, more precise detection of a leak s location.

  9. Safe management of spent radiation source

    International Nuclear Information System (INIS)

    Kosako, Toshiso; Sugiura, Nobuyuki; Valdezco, E.M.; Choi, Kwang-Sub

    2003-01-01

    Presented are 8 investigation reports concerning the safe management of spent radiation source (SRS) during the current 2 years. Four reports from Japan are: Scheme for SRS management (approach and present status of the SRS management and consideration toward solving problems); Current International Atomic Energy Agency (IAEA) activities related to safety of radiation sources (Chronology of action plan development, Outline of revised action plan, and Asian regional activities); Current status of SRS management in Japan (Regulation system, Obligations of licensed users, Regulatory system on sealed sources, Status in the incidents on sources occurred, Incident of source loss, and Incidents of orphan sources); and SRS management system in Japan (Current status of using of sealed sources, collection system of SRS-Japan Radioisotope Association (JRIA) services, and Disposal of SRS). Four reports from the Asian countries also concern the current statuses of SRS management in the Philippine (Radioactive waste sources, Waste management strategies, Conditioning of Ra sources, Ra project action plan, as low as reasonably achievable (ALARA) program, Dose assessment, Regulations on radioactive waste, Action plan on the safety and security of sources, IAEA Regional Demonstration Centers, and sitting studies for a near surface disposal facility); Thailand (Current status of using sealed sources, Inventory of SRS, and Current topics of SRS management); Indonesia (Principles of management of radiation sources, Legislative framework of SRS management practices, Regulatory on SRS, management of sealed SRS, management hurdles, and reported incidents); and Korea (Regulatory frame work, Collection systems of SRS, Radioisotope waste generation, Radiation exposure incident, and Scrap monitoring system). (N.I.)

  10. Proceedings of TopSafe 2008 Transactions

    International Nuclear Information System (INIS)

    2008-01-01

    The aim of the conference is to provide a forum for addressing the current status and future perspectives with regards to safety at nuclear installations worldwide. Previous TopSafe editions took place in Budapest (1995) and Valencia (1998). The conference is directed at a broad range of experts in the area of nuclear safety, including professionals from the different disciplines involved in the safety of nuclear power plants, installations in other parts of the fuel cycle, and research reactors. It is aimed at professionals coming from the research organisations, universities, vendors, operators, regulatory bodies as well as policy makers. Top level representatives of the Countries that are constructing new nuclear power plants are invited. Regulators of all individual Countries with nuclear programme are expected to contribute the Conference. The topics of the conference are: Safety Issues of Operating Power Plants PWR and BWR, CANDU, WWER, RBMK; Application of European Utilities Requirements; Probabilistic and Deterministic Analysis; Shutdown Safety; Advances in Safety: Analysis Codes and Techniques; Severe Accidents Management; International Safety Studies; Emergency Planning; Risk Informed Application and Licensing; Regulatory Safety Requirements; Ageing and Life Extension; Power Upgrades and Relevant Topics; Management of Safety and Quality; Safety Culture and Self Assessment; Political and Public Perception of Nuclear Energy; Nuclear Power Plant Security; Safety Issues of Future Power Plants-Near term deployment reactors (EPR, SWR1000, AP1000, ESBWR, SBWR, ACR-1000) and Generation IV reactors; Safety Issues of Research Reactors (pool type and others); Fuel Cycle Facilities Safety-Uranium mining and conversion, enrichment and fuel production, reprocessing and transmutation, waste disposal. (authors)

  11. Organic Substances from Unconventional Oil and Gas Production in Shale

    Science.gov (United States)

    Orem, W. H.; Varonka, M.; Crosby, L.; Schell, T.; Bates, A.; Engle, M.

    2014-12-01

    composition of shale formation water, and that some injected organic substances are retained on the shale and slowly released. Thus, appropriate safe disposal of produced water is needed long into production. Changes in organic substances in formation water may impact microbial communities. Current work is focused on UOG production in the Permian Basin, Texas.

  12. Substance Abuse Among Blacks Across the Diaspora.

    Science.gov (United States)

    Lacey, Krim K; Mouzon, Dawne M; Govia, Ishtar O; Matusko, Niki; Forsythe-Brown, Ivy; Abelson, Jamie M; Jackson, James S

    2016-07-28

    Lower rates of substance abuse are found among Black Americans compared to Whites, but little is known about differences in substance abuse across ethnic groups within the black population. We examined prevalence rates of substance abuse among Blacks across three geographic regions (US, Jamaica, Guyana). The study also sought to ascertain whether length of time, national context and major depressive episodes (MDE) were associated with substance abuse. We utilized three different data sources based upon probability samples collected in three different countries. The samples included 3,570 African Americans and 1,621 US Caribbean Black adults from the 2001-2003 National Survey of American Life (NSAL). An additional 1,142 Guyanese Blacks and 1,176 Jamaican Blacks living in the Caribbean region were included from the 2005 NSAL replication extension study, Family Connections Across Generations and Nations (FCGN). Mental disorders were based upon DSM-IV criteria. For the analysis, we used descriptive statistics, chi-square, and multivariate logistic regression analytic procedures. Prevalence of substance abuse varied by national context, with higher rates among Blacks within the United States compared to the Caribbean region. Rates of substance abuse were lower overall for women, but differ across cohorts by nativity and length of time in the United States, and in association with major depressive episode. The study highlights the need for further examination of how substance abuse disparities between US-based and Caribbean-based populations may become manifested.

  13. Substance use and motivation: a longitudinal perspective.

    Science.gov (United States)

    Korcha, Rachael A; Polcin, Douglas L; Bond, Jason C; Lapp, William M; Galloway, Gantt

    2011-01-01

    Motivation to change substance use behavior is an important component of the recovery process that has usually been studied at entry into treatment. Less studied, but equally important, is the measurement of motivation over time and the role motivation plays in subsequent substance use. The present study sought to examine longitudinal motivation toward sobriety among residents of sober living houses. Sober living residents (n = 167) were followed at 6-month intervals over an 18-month period and assessed for motivation and substance use outcomes at each study interview. Motivation was measured using the costs and benefits subscales of the Alcohol and Drug Consequences Questionnaire (ADCQ) and substance use outcomes included the Addiction Severity Index (ASI) alcohol scale, ASI drug scale, and peak density of substance use (number of days of most use in a month). Participants reported higher benefits than costs of sobriety or cutting down substance use at every study time point. Using lagged generalized estimating equation models, the ADCQ costs predicted increased severity for alcohol, drugs, and peak density, whereas the benefits subscale predicted decreased drug and peak density. Longitudinal measurement of motivation can be a useful clinical tool to understand later substance use problems. Given the mixed findings from prior studies on the effects of baseline motivation, a shift toward examining longitudinal measures of motivation at proximal and temporal intervals is indicated.

  14. Ozone depleting substances management inventory system

    Directory of Open Access Journals (Sweden)

    Felix Ivan Romero Rodríguez

    2018-02-01

    Full Text Available Context: The care of the ozone layer is an activity that contributes to the planet's environmental stability. For this reason, the Montreal Protocol is created to control the emission of substances that deplete the ozone layer and reduce its production from an organizational point of view. However, it is also necessary to have control of those that are already circulating and those present in the equipment that cannot be replaced yet because of the context of the companies that keep it. Generally, the control mechanisms for classifying the type of substances, equipment and companies that own them, are carried in physical files, spreadsheets and text documents, which makes it difficult to control and manage the data stored in them. Method: The objective of this research is to computerize the process of control of substances that deplete the ozone layer. An evaluation and description of all process to manage Ozone-Depleting Substances (ODS, and its alternatives, is done. For computerization, the agile development methodology SCRUM is used, and for the technological solution tools and free open source technologies are used. Result: As a result of the research, a computer tool was developed that automates the process of control and management of substances that exhaust the ozone layer and its alternatives. Conclusions: The developed computer tool allows to control and manage the ozone-depleting substances and the equipment that use them. It also manages the substances that arise as alternatives to be used for the protection of the ozone layer.

  15. Safe havens in Europe: Switzerland and the ten dwarfs

    Directory of Open Access Journals (Sweden)

    Martin Paldam

    2013-12-01

    Full Text Available Eleven safe havens exist in Europe providing offshore banking and low taxes. Ten of these states are very small while Switzerland is moderately small. All 11countries are richer than their large neighbors. It is shown that causality is from small to safe haven towealth, and that theoretically equilibriums are likely to exist where a certain regulation is substantially lower in a small country than in its big neighbor. This generates a large capital inflow to the safe havens. The pool of funds that may reach the safe havens is shown to be huge. It is far in excess of the absorptive capacity of the safe havens, but it still explains, why they are rich. Microstates offer a veil of anonymity to funds passing through, and Switzerland offers safe storage of funds.

  16. [Adolescent substance use and family problems].

    Science.gov (United States)

    Malbergier, André; Cardoso, Luciana Roberta Donola; Amaral, Ricardo Abrantes do

    2012-04-01

    This study aimed to evaluate the association between substance use (alcohol, tobacco, and illicit drugs) and family problems among 965 adolescents from 50 public schools in two cities in São Paulo State, Brazil, in 2007. The Drug Use Screening Inventory (DUSI) was used for data collection. Use of alcohol, tobacco, and illicit drugs was associated with a negative assessment of the family relationship, lack of monitoring/support, and psychoactive substance use by family members (p illicit drugs had more family problems than those who did not consume any substance (p illicit drugs (p illicit drug use.

  17. Advances on functional neuroimaging in substance misuse

    International Nuclear Information System (INIS)

    Lv Rongbin; Liu Xingdang; Han Mei

    2009-01-01

    Over the past decade, functional neuroimaging has contributed greatly to our knowledge about the neuropharmacology of substance misuse in man. In this review, discussed the application and the progress of the positron emission tomography, single photon emission computed tomography and functional magnetic resonance imaging in the substance misuse. After reading some papers, found that the dopamine transporter was significantly decreased in the brain of subjects with heroin abuse. Also observed a significant decrease of regional cerebral blood flow in bilateral cerebral frontal lobes, temporal lobes, the insula and the ipsilateral basal nuclei in substance misuse subjects. Taken together, functional images will lead the direction in future research formedication development of addiction treatment. (authors)

  18. Continuum mechanics of single-substance bodies

    CERN Document Server

    Eringen, A Cemal

    1975-01-01

    Continuum Physics, Volume II: Continuum Mechanics of Single-Substance Bodies discusses the continuum mechanics of bodies constituted by a single substance, providing a thorough and precise presentation of exact theories that have evolved during the past years. This book consists of three parts-basic principles, constitutive equations for simple materials, and methods of solution. Part I of this publication is devoted to a discussion of basic principles irrespective of material geometry and constitution that are valid for all kinds of substances, including composites. The geometrical notions, k

  19. Former substance users working as counselors

    DEFF Research Database (Denmark)

    Hecksher, Dorte

    2007-01-01

    All helping professionals risk participation in "dual relationships". But in the case of former substance users working as counselors, specific dilemmas and problems are accentuated. A qualitative analysis highlights some of the ethical and personal dilemmas faced by these counselors. The data...... is derived from an interview study initiated in 2000 in Denmark on former substance users with 4 -8 years of abstinence. Through an analysis of interview data from a larger group of former substance users, it became evident that those working as counselors experienced specific dilemmas and problems...

  20. A Privacy Analysis of Google and Yandex Safe Browsing

    OpenAIRE

    Gerbet , Thomas; Kumar , Amrit; Lauradoux , Cédric

    2015-01-01

    Google and Yandex Safe Browsing are popular services included in many webbrowsers to prevent users from visiting phishing or malware website links. If Safe Browsing servicesprotect their users from losing private information, they also require that their servers receivebrowsing information on the very same users. In this paper, we present an analysis of Googleand Yandex Safe Browsing services from a privacy perspective. We quantify the privacy providedby these services by analyzing the possib...