WorldWideScience

Sample records for susceptibility signal dropout

  1. Dynamic Education Signaling with Dropout, Second Version

    OpenAIRE

    Francesc Dilme; Fei Li

    2012-01-01

    We study students' dropout behavior and its consequences in a dynamic signaling model. Workers pay an education cost per unit of time and cannot commit to a fixed education length. Workers face an exogenous dropout risk before graduation. Since low-productivity students' cost is high, pooling with early dropouts helps them to avoid a high education cost. In equilibrium, low-productivity students choose to endogenously drop out over time, so the productivity of students in college increases al...

  2. Dynamic Education Signaling with Dropout Risk, Third Version

    OpenAIRE

    Francesc Dilme; Fei Li

    2013-01-01

    This paper analyzes a dynamic education signaling model with dropout risk. Workers pay an education cost per unit of time and face an exogenous dropout risk before graduation. Since low-productivity workers’ cost of education is high, pooling with early dropouts helps them avoid a high education cost. In equilibrium, low-productivity workers choose to endoge- nously drop out over time, so the productivity of workers in college increases as the education process progresses. We find that the ex...

  3. Designing hyperbolic secant excitation pulses to reduce signal dropout in gradient-echo echo-planar imaging.

    Science.gov (United States)

    Wastling, Stephen J; Barker, Gareth J

    2015-09-01

    To design hyperbolic secant (HS) excitation pulses to reduce signal dropout in the orbitofrontal and inferior temporal regions in gradient-echo echo-planar imaging (GE-EPI) for functional MRI (fMRI) applications. An algorithm based on Bloch simulations optimizes the HS pulse parameters needed to give the desired signal response across the range of susceptibility gradients observed in the human head (approximately ±250 μT·m(-1) ). The impact of the HS pulse on the signal, temporal signal-to-noise ratio, blood oxygen level-dependent (BOLD) sensitivity, and ability to detect resting state BOLD signal changes was assessed in six healthy male volunteers at 3T. The optimized HS pulse (μ = 4.25, β = 3040 Hz, A0 = 12.3 μT, Δf = 4598 Hz) had a near uniform signal response for through-plane susceptibility gradients in the range ±250 μT·m(-1) . Signal, temporal signal-to-noise ratio, BOLD sensitivity, and the detectability of resting state networks were all partially recovered in the orbitofrontal and inferior temporal regions; however, there were signal losses of up to 50% in regions of homogeneous field (and signal loss from in-plane susceptibility gradients remained). The HS pulse reduced signal dropout and could be used to acquire task and resting state fMRI data without loss of spatial coverage or temporal resolution. © 2014 Wiley Periodicals, Inc.

  4. School dropout susceptibility mapping with fuzzy logic – a study in the District of Purulia, India

    Directory of Open Access Journals (Sweden)

    Mukunda Mishra

    2017-05-01

    Full Text Available Multi-input prediction models are gradually finding their places in the arena of social and economic sciences to assess, locate and address the complicated socio-economic issues arising around the globe. These models treat the problems as the output aroused from a complex interaction between a range of variables linked with physical, socio-cultural, economic as well as ambient political systems. The discussion on dropout from the education system belongs to the core of the educational researchers. The researchers within this domain are attempting to develop the ‘tools and techniques’ for efficiently demarcating the space with a given degree of susceptibility. The scope is to drop out and examine the internal functions of the interactive variables associated with the process. In the present study, we try to apply the fuzzy logic in mapping the spatial variation of the susceptibility of school dropout in the district of Purulia, a backwards district in India regarding achieved level of human development. The training datasets for building the fuzzy model based on the available secondary data from different reports published by the Government and a range of primary data collected through a socio-economic survey. The model output is an index, namely the Index of Susceptibility of School Drop Out (ISDO which reflects the levels of susceptibility to school dropout at different parts of the study area. The proposed model should allow the success within the larger social and economic system.

  5. Restoring susceptibility induced MRI signal loss in rat brain at 9.4 T: A step towards whole brain functional connectivity imaging.

    Directory of Open Access Journals (Sweden)

    Rupeng Li

    Full Text Available The aural cavity magnetic susceptibility artifact leads to significant echo planar imaging (EPI signal dropout in rat deep brain that limits acquisition of functional connectivity fcMRI data. In this study, we provide a method that recovers much of the EPI signal in deep brain. Needle puncture introduction of a liquid-phase fluorocarbon into the middle ear allows acquisition of rat fcMRI data without signal dropout. We demonstrate that with seeds chosen from previously unavailable areas, including the amygdala and the insular cortex, we are able to acquire large scale networks, including the limbic system. This tool allows EPI-based neuroscience and pharmaceutical research in rat brain using fcMRI that was previously not feasible.

  6. Phase processing for quantitative susceptibility mapping of regions with large susceptibility and lack of signal.

    Science.gov (United States)

    Fortier, Véronique; Levesque, Ives R

    2017-11-11

    Phase processing impacts the accuracy of quantitative susceptibility mapping (QSM). Techniques for phase unwrapping and background removal have been proposed and demonstrated mostly in brain. In this work, phase processing was evaluated in the context of large susceptibility variations (Δχ) and negligible signal, in particular for susceptibility estimation using the iterative phase replacement (IPR) algorithm. Continuous Laplacian, region-growing, and quality-guided unwrapping were evaluated. For background removal, Laplacian boundary value (LBV), projection onto dipole fields (PDF), sophisticated harmonic artifact reduction for phase data (SHARP), variable-kernel sophisticated harmonic artifact reduction for phase data (V-SHARP), regularization enabled sophisticated harmonic artifact reduction for phase data (RESHARP), and 3D quadratic polynomial field removal were studied. Each algorithm was quantitatively evaluated in simulation and qualitatively in vivo. Additionally, IPR-QSM maps were produced to evaluate the impact of phase processing on the susceptibility in the context of large Δχ with negligible signal. Quality-guided unwrapping was the most accurate technique, whereas continuous Laplacian performed poorly in this context. All background removal algorithms tested resulted in important phase inaccuracies, suggesting that techniques used for brain do not translate well to situations where large Δχ and no or low signal are expected. LBV produced the smallest errors, followed closely by PDF. Results suggest that quality-guided unwrapping should be preferred, with PDF or LBV for background removal, for QSM in regions with large Δχ and negligible signal. This reduces the susceptibility inaccuracy introduced by phase processing. Accurate background removal remains an open question. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  7. Oscillation of Angiogenesis and Vascular Dropout in Progressive Human Vascular Disease. [Vascular Pattern as Useful Read-Out of Complex Molecular Signaling

    Science.gov (United States)

    Parsons-Wingerter, Patricia

    2010-01-01

    When analyzed by VESsel GENeration Analysis (VESGEN) software, vascular patterns provide useful integrative read-outs of complex, interacting molecular signaling pathways. Using VESGEN, we recently discovered and published our innovative, surprising findings that angiogenesis oscillated with vascular dropout throughout progression of diabetic retinopathy, a blinding vascular disease. Our findings provide a potential paradigm shift in the current prevailing view on progression and treatment of this disease, and a new early-stage window of regenerative therapeutic opportunities. The findings also suggest that angiogenesis may oscillate with vascular disease in a homeostatic-like manner during early stages of other inflammatory progressive diseases such as cancer and coronary vascular disease.

  8. Purification and Concentration of PCR Products Leads to Increased Signal intensities with Fewer Allelic Drop-Outs and Artifacts

    DEFF Research Database (Denmark)

    Maria Irlund Pedersen, Line; Stangegaard, Michael; Mogensen, Helle Smidt

    2011-01-01

    Capillary electrophoresis of amplified DNA isolated from trace evidence samples occasionally results in inadequate STR-profiles due to artifacts caused by e.g. primers and dNTPs. Removal of artifacts by purification and subsequent concentration of the PCR products may increase the sensitivity...... and the quality of the DNA profiles without re-amplification of the sample. We have validated and implemented an automated method to purify and 2-fold concentrate PCR products resulting in allelic peaks with higher intensity (a median height across all loci from 130 to 404 RFU), fewer allelic dropouts...... and a reduced number of artifacts compared to both an increase in injection time and increase in the number of amplification cycles....

  9. Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

    Directory of Open Access Journals (Sweden)

    Kelly M. Shepardson

    2016-05-01

    Full Text Available Bacterial superinfections are a primary cause of death during influenza pandemics and epidemics. Type I interferon (IFN signaling contributes to increased susceptibility of mice to bacterial superinfection around day 7 post-influenza A virus (IAV infection. Here we demonstrate that the reduced susceptibility to methicillin-resistant Staphylococcus aureus (MRSA at day 3 post-IAV infection, which we previously reported was due to interleukin-13 (IL-13/IFN-γ responses, is also dependent on type I IFN signaling and its subsequent requirement for protective IL-13 production. We found, through utilization of blocking antibodies, that reduced susceptibility to MRSA at day 3 post-IAV infection was IFN-β dependent, whereas the increased susceptibility at day 7 was IFN-α dependent. IFN-β signaling early in IAV infection was required for MRSA clearance, whereas IFN-α signaling late in infection was not, though it did mediate increased susceptibility to MRSA at that time. Type I IFN receptor (IFNAR signaling in CD11c+ and Ly6G+ cells was required for the observed reduced susceptibility at day 3 post-IAV infection. Depletion of Ly6G+ cells in mice in which IFNAR signaling was either blocked or deleted indicated that Ly6G+ cells were responsible for the IFNAR signaling-dependent susceptibility to MRSA superinfection at day 7 post-IAV infection. Thus, during IAV infection, the temporal differences in type I IFN signaling increased bactericidal activity of both CD11c+ and Ly6G+ cells at day 3 and reduced effector function of Ly6G+ cells at day 7. The temporal differential outcomes induced by IFN-β (day 3 and IFN-α (day 7 signaling through the same IFNAR resulted in differential susceptibility to MRSA at 3 and 7 days post-IAV infection.

  10. TGF-β signaling alterations and susceptibility to colorectal cancer

    OpenAIRE

    Xu, Yanfei; Pasche, Boris

    2007-01-01

    In 2006, more than 55 000 patients died of colorectal cancer in the US, accounting for ∼10% of all cancer deaths. Despite significant progress in screening combined with the development of novel effective therapies, colorectal cancer ranks second to lung cancer as a cause of cancer death. Twin studies indicate that 35% of all colorectal cancers are inherited, but high-penetrance tumor susceptibility genes only account for ∼3–6% of all cases. The remainder of the unexplained familial risk is p...

  11. Dropout Phenomena at Universities

    DEFF Research Database (Denmark)

    Larsen, Michael Søgaard; Kornbeck, Kasper Pihl; Kristensen, Rune

    Dropout from university studies comprises a number of complex phenomena with serious complex consequences and profound political attention. Further analysis of the field is, therefore, warranted. Such an analysis is offered here as a systematic review which gives answers based on the best possible...... evidence found in the research field comprised by the three review questions to be addressed. The aims of this systematic review can, thus, be summarized like this: Which answers can be offered from research in relation to the following questions: What is dropout from university studies? Why do...... such dropout phenomena occur at universities? What can be done by the universities to prevent or reduce such dropout phenomena?...

  12. Electromagnetic Compatibility Testing for Conducted Susceptibility Along Interconnecting Signal Lines. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Ewing, P. D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wood, R. T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Korsah, K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Shourbaji, A. A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wilson, T. L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Beets, B. M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2002-07-31

    This document presents recommendations and the associated technical basis for addressing the effects of conducted electromagnetic interference (EMI) and radio-frequency interference (RFI) along interconnecting signal lines in safety-related instrumentation and control (I&C) systems. Oak Ridge National Laboratory has been engaged in assisting the U.S. Nuclear Regulatory Commission Office of Nuclear Regulatory Research in developing the technical basis for regulatory guidance on EMIIRFI immunity and power surge withstand capability (SWC). Previous research efforts have provided recommendations on (1) electromagnetic compatibility design and installation practices, (2) the endorsement of EMI/RFI and SWC test criteria and test methods, (3) the determination of ambient electromagnetic conditions at nuclear power plants, and (4) the development of recommended electromagnetic operating envelopes applicable to locations where safety-related I&C systems will be installed. The current research focuses on the susceptibility of l&C systems to conducted EMIIRFI along interconnecting signal lines. Coverage of signal line susceptibility was identified as an open issue in previous research on establishing the technical basis for EMIIRFI and SWC in safety-related I&C systems. Research results provided in this report will be used to establish the technical basis for endorsing U.S. Department of Defense and European Committee for Electrotechnical Standardization test criteria and test methods that address signal-line susceptibility. In addition, recommendations on operating envelopes are presented based on available technical information.

  13. [Dropout behavior during inpatient psychotherapy ].

    Science.gov (United States)

    Martens, Ute; Rempel, Irene; Zipfel, Stephan; Enck, Paul; Teufel, Martin

    2014-01-01

    Dropouts result in far-reaching consequences for the individual patient, fellow patients, therapists, and the clinic. This study was aimed at early identification of patients with a dropout risk. Data from patients of the Department of Psychosomatic Medicine and Psychotherapy of the Medical University Clinic of Tübingen (Germany) were analyzed retrospectively in a case-control study (matched). Differences in the results of various questionnaires (SCL-90-R, IIP-D, SF-36) regarding reasons for dropout and sociodemographic data were analyzed. A total of 59 dropouts, 50 females and 9 males, were included. They were split into 28 early dropouts and 31 late dropouts. The data were compared between early and late dropouts and control group. Early dropouts were significantly younger than late dropouts; they tended to live with their parents or on their own, and suffered more frequently from eating disorders. Late dropouts lived together with partners and suffered from somatoform disorders more frequently than early dropouts. The reasons given for dropout did not differ between the groups. No differences between dropouts and the controls were found with respect to psychopathology (SCL- 90-R) and quality of life (SF-36). Late dropouts did show significantly lower scores on the scale "autocracy/dominance" than the controls (IIP). Therapy dropout is a multifactorial occurrence. It is generally not predictable, though it may be predicted with different instruments on the basis of a diagnosis, especially with respect to interpersonal behavior patterns. In further studies, targeted interventions should be developed and tested which enable procedures to minimize the risk of dropout and to achieve complete treatment according to patients' intentions.

  14. Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis.

    Science.gov (United States)

    Xia, Tianli; Konno, Hiroyasu; Barber, Glen N

    2016-11-15

    The innate immunoregulator STING stimulates cytokine production in response to the presence of cytosolic DNA, which can arise following DNA damage. Extrinsic STING signaling is also needed for antigen-presenting cells to stimulate antitumor T-cell immunity. Here, we show that STING signaling is recurrently suppressed in melanoma cells, where this event may enable immune escape after DNA damage. Mechanistically, STING signaling was suppressed most frequently by epigenetic silencing of either STING or the cyclic GMP-AMP synthase, which generates STING-activating cyclic dinucleotides after binding cytosolic DNA species. Loss of STING function rendered melanoma cells unable to produce type I IFN and other immune cytokines after exposure to cytosolic DNA species. Consequently, such cells were highly susceptible to infection with DNA viruses including HSV1, a variant of which is being developed presently as a therapeutic oncolytic virus [talimogene laherparepvec (T-VEC)]. Our findings provide insight into the basis for susceptibility to viral oncolysis by agents such as HSV1. Cancer Res; 76(22); 6747-59. ©2016 AACR. ©2016 American Association for Cancer Research.

  15. High School Dropouts in California

    Science.gov (United States)

    Lucile Packard Foundation for Children's Health, 2011

    2011-01-01

    Kidsdata.org shows the California Department of Education's adjusted four-year derived dropout rate, which reflects the estimated percentage of public high school dropouts over four years based on a single year's data, and the grade 9-12 dropout count. Data also are provided by race/ethnicity. This paper presents the statistics on high school…

  16. Pathogen-triggered ethylene signaling mediates systemic-induced susceptibility to herbivory in Arabidopsis.

    Science.gov (United States)

    Groen, Simon C; Whiteman, Noah K; Bahrami, Adam K; Wilczek, Amity M; Cui, Jianping; Russell, Jacob A; Cibrian-Jaramillo, Angelica; Butler, Ian A; Rana, Jignasha D; Huang, Guo-Hua; Bush, Jenifer; Ausubel, Frederick M; Pierce, Naomi E

    2013-11-01

    Multicellular eukaryotic organisms are attacked by numerous parasites from diverse phyla, often simultaneously or sequentially. An outstanding question in these interactions is how hosts integrate signals induced by the attack of different parasites. We used a model system comprised of the plant host Arabidopsis thaliana, the hemibiotrophic bacterial phytopathogen Pseudomonas syringae, and herbivorous larvae of the moth Trichoplusia ni (cabbage looper) to characterize mechanisms involved in systemic-induced susceptibility (SIS) to T. ni herbivory caused by prior infection by virulent P. syringae. We uncovered a complex multilayered induction mechanism for SIS to herbivory. In this mechanism, antiherbivore defenses that depend on signaling via (1) the jasmonic acid-isoleucine conjugate (JA-Ile) and (2) other octadecanoids are suppressed by microbe-associated molecular pattern-triggered salicylic acid (SA) signaling and infection-triggered ethylene signaling, respectively. SIS to herbivory is, in turn, counteracted by a combination of the bacterial JA-Ile mimic coronatine and type III virulence-associated effectors. Our results show that SIS to herbivory involves more than antagonistic signaling between SA and JA-Ile and provide insight into the unexpectedly complex mechanisms behind a seemingly simple trade-off in plant defense against multiple enemies.

  17. Dropouts and Training.

    Science.gov (United States)

    Sullivan, Terry

    1984-01-01

    Exploring the uses of human capital theory to an analysis of effective adult education, the author tests several hypotheses. Focusing on teacher characteristics, he examines whether trained teachers are better than untrained and whether dropout rates are affected by adult education teacher training. (SK)

  18. Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics.

    Science.gov (United States)

    Dorhoi, Anca; Yeremeev, Vladimir; Nouailles, Geraldine; Weiner, January; Jörg, Sabine; Heinemann, Ellen; Oberbeck-Müller, Dagmar; Knaul, Julia K; Vogelzang, Alexis; Reece, Stephen T; Hahnke, Karin; Mollenkopf, Hans-Joachim; Brinkmann, Volker; Kaufmann, Stefan H E

    2014-08-01

    General interest in the biological functions of IFN type I in Mycobacterium tuberculosis (Mtb) infection increased after the recent identification of a distinct IFN gene expression signature in tuberculosis (TB) patients. Here, we demonstrate that TB-susceptible mice lacking the receptor for IFN I (IFNAR1) were protected from death upon aerogenic infection with Mtb. Using this experimental model to mimic primary progressive pulmonary TB, we dissected the immune processes affected by IFN I. IFNAR1 signaling did not affect T-cell responses, but markedly altered migration of inflammatory monocytes and neutrophils to the lung. This process was orchestrated by IFNAR1 expressed on both immune and tissue-resident radioresistant cells. IFNAR1-driven TB susceptibility was initiated by augmented Mtb replication and in situ death events, along with CXCL5/CXCL1-driven accumulation of neutrophils in alveoli, followed by the discrete compartmentalization of Mtb in lung phagocytes. Early depletion of neutrophils rescued TB-susceptible mice to levels observed in mice lacking IFNAR1. We conclude that IFN I alters early innate events at the site of Mtb invasion leading to fatal immunopathology. These data furnish a mechanistic explanation for the detrimental role of IFN I in pulmonary TB and form a basis for understanding the complex roles of IFN I in chronic inflammation. © 2014 The Authors. European Journal of Immunology published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.

    Science.gov (United States)

    Elks, Philip M; Brizee, Sabrina; van der Vaart, Michiel; Walmsley, Sarah R; van Eeden, Fredericus J; Renshaw, Stephen A; Meijer, Annemarie H

    2013-01-01

    Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and develop a niche permissive for proliferation and dissemination. Understanding of the pathogenesis of mycobacterial infections such as tuberculosis (TB) remains limited, especially for early infection and for reactivation of latent infection. Signaling via hypoxia inducible factor α (HIF-α) transcription factors has previously been implicated in leukocyte activation and host defence. We have previously shown that hypoxic signaling via stabilization of Hif-1α prolongs the functionality of leukocytes in the innate immune response to injury. We sought to manipulate Hif-α signaling in a well-established Mycobacterium marinum (Mm) zebrafish model of TB to investigate effects on the host's ability to combat mycobacterial infection. Stabilization of host Hif-1α, both pharmacologically and genetically, at early stages of Mm infection was able to reduce the bacterial burden of infected larvae. Increasing Hif-1α signaling enhanced levels of reactive nitrogen species (RNS) in neutrophils prior to infection and was able to reduce larval mycobacterial burden. Conversely, decreasing Hif-2α signaling enhanced RNS levels and reduced bacterial burden, demonstrating that Hif-1α and Hif-2α have opposing effects on host susceptibility to mycobacterial infection. The antimicrobial effect of Hif-1α stabilization, and Hif-2α reduction, were demonstrated to be dependent on inducible nitric oxide synthase (iNOS) signaling at early stages of infection. Our findings indicate that induction of leukocyte iNOS by stabilizing Hif-1α, or reducing Hif-2α, aids the host during early stages of Mm infection. Stabilization of Hif-1α therefore represents a potential target for therapeutic

  20. Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.

    Directory of Open Access Journals (Sweden)

    Philip M Elks

    Full Text Available Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb, becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and develop a niche permissive for proliferation and dissemination. Understanding of the pathogenesis of mycobacterial infections such as tuberculosis (TB remains limited, especially for early infection and for reactivation of latent infection. Signaling via hypoxia inducible factor α (HIF-α transcription factors has previously been implicated in leukocyte activation and host defence. We have previously shown that hypoxic signaling via stabilization of Hif-1α prolongs the functionality of leukocytes in the innate immune response to injury. We sought to manipulate Hif-α signaling in a well-established Mycobacterium marinum (Mm zebrafish model of TB to investigate effects on the host's ability to combat mycobacterial infection. Stabilization of host Hif-1α, both pharmacologically and genetically, at early stages of Mm infection was able to reduce the bacterial burden of infected larvae. Increasing Hif-1α signaling enhanced levels of reactive nitrogen species (RNS in neutrophils prior to infection and was able to reduce larval mycobacterial burden. Conversely, decreasing Hif-2α signaling enhanced RNS levels and reduced bacterial burden, demonstrating that Hif-1α and Hif-2α have opposing effects on host susceptibility to mycobacterial infection. The antimicrobial effect of Hif-1α stabilization, and Hif-2α reduction, were demonstrated to be dependent on inducible nitric oxide synthase (iNOS signaling at early stages of infection. Our findings indicate that induction of leukocyte iNOS by stabilizing Hif-1α, or reducing Hif-2α, aids the host during early stages of Mm infection. Stabilization of Hif-1α therefore represents a potential target for

  1. AtWRKY22 promotes susceptibility to aphids and modulates salicylic acid and jasmonic acid signalling.

    Science.gov (United States)

    Kloth, Karen J; Wiegers, Gerrie L; Busscher-Lange, Jacqueline; van Haarst, Jan C; Kruijer, Willem; Bouwmeester, Harro J; Dicke, Marcel; Jongsma, Maarten A

    2016-05-01

    Aphids induce many transcriptional perturbations in their host plants, but the signalling cascades responsible and the effects on plant resistance are largely unknown. Through a genome-wide association (GWA) mapping study in Arabidopsis thaliana, we identified WRKY22 as a candidate gene associated with feeding behaviour of the green peach aphid, Myzus persicae The transcription factor WRKY22 is known to be involved in pathogen-triggered immunity, and WRKY22 gene expression has been shown to be induced by aphids. Assessment of aphid population development and feeding behaviour on knockout mutants and overexpression lines showed that WRKY22 increases susceptibility to M. persicae via a mesophyll-located mechanism. mRNA sequencing analysis of aphid-infested wrky22 knockout plants revealed the up-regulation of genes involved in salicylic acid (SA) signalling and down-regulation of genes involved in plant growth and cell-wall loosening. In addition, mechanostimulation of knockout plants by clip cages up-regulated jasmonic acid (JA)-responsive genes, resulting in substantial negative JA-SA crosstalk. Based on this and previous studies, WRKY22 is considered to modulate the interplay between the SA and JA pathways in response to a wide range of biotic and abiotic stimuli. Its induction by aphids and its role in suppressing SA and JA signalling make WRKY22 a potential target for aphids to manipulate host plant defences. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  2. AtWRKY22 promotes susceptibility to aphids and modulates salicylic acid and jasmonic acid signalling

    Science.gov (United States)

    Kloth, Karen J.; Wiegers, Gerrie L.; Busscher-Lange, Jacqueline; van Haarst, Jan C.; Kruijer, Willem; Bouwmeester, Harro J.; Dicke, Marcel; Jongsma, Maarten A.

    2016-01-01

    Aphids induce many transcriptional perturbations in their host plants, but the signalling cascades responsible and the effects on plant resistance are largely unknown. Through a genome-wide association (GWA) mapping study in Arabidopsis thaliana, we identified WRKY22 as a candidate gene associated with feeding behaviour of the green peach aphid, Myzus persicae. The transcription factor WRKY22 is known to be involved in pathogen-triggered immunity, and WRKY22 gene expression has been shown to be induced by aphids. Assessment of aphid population development and feeding behaviour on knockout mutants and overexpression lines showed that WRKY22 increases susceptibility to M. persicae via a mesophyll-located mechanism. mRNA sequencing analysis of aphid-infested wrky22 knockout plants revealed the up-regulation of genes involved in salicylic acid (SA) signalling and down-regulation of genes involved in plant growth and cell-wall loosening. In addition, mechanostimulation of knockout plants by clip cages up-regulated jasmonic acid (JA)-responsive genes, resulting in substantial negative JA–SA crosstalk. Based on this and previous studies, WRKY22 is considered to modulate the interplay between the SA and JA pathways in response to a wide range of biotic and abiotic stimuli. Its induction by aphids and its role in suppressing SA and JA signalling make WRKY22 a potential target for aphids to manipulate host plant defences. PMID:27107291

  3. The School Dropout: Causes, Effects and Solutions.

    Science.gov (United States)

    Cinal, Terry Lynn

    This document reviews the literature on elementary and secondary school dropouts and notes the effects and possible solutions to the dropout problem. Statistical findings about dropouts from the 1960's to the present are presented along with methods of predicting who the dropouts will be. Dropout characteristics, including psychological, social,…

  4. Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice.

    Science.gov (United States)

    Dorfman, Mauricio D; Krull, Jordan E; Douglass, John D; Fasnacht, Rachael; Lara-Lince, Fernando; Meek, Thomas H; Shi, Xiaogang; Damian, Vincent; Nguyen, Hong T; Matsen, Miles E; Morton, Gregory J; Thaler, Joshua P

    2017-02-22

    Female mice are less susceptible to the negative metabolic consequences of high-fat diet feeding than male mice, for reasons that are incompletely understood. Here we identify sex-specific differences in hypothalamic microglial activation via the CX3CL1-CX3CR1 pathway that mediate the resistance of female mice to diet-induced obesity. Female mice fed a high-fat diet maintain CX3CL1-CX3CR1 levels while male mice show reductions in both ligand and receptor expression. Female Cx3cr1 knockout mice develop 'male-like' hypothalamic microglial accumulation and activation, accompanied by a marked increase in their susceptibility to diet-induced obesity. Conversely, increasing brain CX3CL1 levels in male mice through central pharmacological administration or virally mediated hypothalamic overexpression converts them to a 'female-like' metabolic phenotype with reduced microglial activation and body-weight gain. These data implicate sex differences in microglial activation in the modulation of energy homeostasis and identify CX3CR1 signalling as a potential therapeutic target for the treatment of obesity.

  5. Jasmonate signalling drives time-of-day differences in susceptibility of Arabidopsis to the fungal pathogen Botrytis cinerea.

    Science.gov (United States)

    Ingle, Robert A; Stoker, Claire; Stone, Wendy; Adams, Nicolette; Smith, Rob; Grant, Murray; Carré, Isabelle; Roden, Laura C; Denby, Katherine J

    2015-12-01

    The circadian clock, an internal time-keeping mechanism, allows plants to anticipate regular changes in the environment, such as light and dark, and biotic challenges such as pathogens and herbivores. Here, we demonstrate that the plant circadian clock influences susceptibility to the necrotrophic fungal pathogen, Botrytis cinerea. Arabidopsis plants show differential susceptibility to B. cinerea depending on the time of day of inoculation. Decreased susceptibility after inoculation at dawn compared with night persists under constant light conditions and is disrupted in dysfunctional clock mutants, demonstrating the role of the plant clock in driving time-of-day susceptibility to B. cinerea. The decreased susceptibility to B. cinerea following inoculation at subjective dawn was associated with faster transcriptional reprogramming of the defence response with gating of infection-responsive genes apparent. Direct target genes of core clock regulators were enriched among the transcription factors that responded more rapidly to infection at subjective dawn than subjective night, suggesting an influence of the clock on the defence-signalling network. In addition, jasmonate signalling plays a crucial role in the rhythmic susceptibility of Arabidopsis to B. cinerea with the enhanced susceptibility to this pathogen at subjective night lost in a jaz6 mutant. © 2015 The Authors The Plant Journal published by Society for Experimental Biology and John Wiley & Sons Ltd.

  6. Dropout in vocational education

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    For the last ten years drop out of vocational education has increased strongly in Denmark. Only half of the students, who take up a vocational programme on upper secondary level, complete it. Like in other European countries the low completion rates has caused considerable alarm on the political...... level (Lamb and Markussen 2011). Continuing high dropout rates will make it very hard for the government to reach its target for educational completion, and the government has launched a series of measures to increase retention including the obligation for all colleges to make plans for retention...

  7. Antagonism between phytohormone signalling underlies the variation in disease susceptibility of tomato plants under elevated CO2

    Science.gov (United States)

    Zhang, Shuai; Li, Xin; Sun, Zenghui; Shao, Shujun; Hu, Lingfei; Ye, Meng; Zhou, Yanhong; Xia, Xiaojian; Yu, Jingquan; Shi, Kai

    2015-01-01

    Increasing CO2 concentrations ([CO2]) have the potential to disrupt plant–pathogen interactions in natural and agricultural ecosystems, but the research in this area has often produced conflicting results. Variations in phytohormone salicylic acid (SA) and jasmonic acid (JA) signalling could be associated with variations in the responses of pathogens to plants grown under elevated [CO2]. In this study, interactions between tomato plants and three pathogens with different infection strategies were compared. Elevated [CO2] generally favoured SA biosynthesis and signalling but repressed the JA pathway. The exposure of plants to elevated [CO2] revealed a lower incidence and severity of disease caused by tobacco mosaic virus (TMV) and by Pseudomonas syringae, whereas plant susceptibility to necrotrophic Botrytis cinerea increased. The elevated [CO2]-induced and basal resistance to TMV and P. syringae were completely abolished in plants in which the SA signalling pathway nonexpressor of pathogenesis-related genes 1 (NPR1) had been silenced or in transgenic plants defective in SA biosynthesis. In contrast, under both ambient and elevated [CO2], the susceptibility to B. cinerea highly increased in plants in which the JA signalling pathway proteinase inhibitors (PI) gene had been silenced or in a mutant affected in JA biosynthesis. However, plants affected in SA signalling remained less susceptible to this disease. These findings highlight the modulated antagonistic relationship between SA and JA that contributes to the variation in disease susceptibility under elevated [CO2]. This information will be critical for investigating how elevated CO2 may affect plant defence and the dynamics between plants and pathogens in both agricultural and natural ecosystems. PMID:25657213

  8. Drop-out probabilities of IrisPlex SNP alleles

    DEFF Research Database (Denmark)

    Andersen, Jeppe Dyrberg; Tvedebrink, Torben; Mogensen, Helle Smidt

    2013-01-01

    In certain crime cases, information about a perpetrator's phenotype, including eye colour, may be a valuable tool if no DNA profile of any suspect or individual in the DNA database matches the DNA profile found at the crime scene. Often, the available DNA material is sparse and allelic drop......-out when the amount of DNA was greater than 125 pg for 29 cycles of PCR and greater than 62 pg for 30 cycles of PCR. With the use of a logistic regression model, we estimated the allele specific probability of drop-out in heterozygote systems based on the signal strength of the observed allele...

  9. Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study.

    Science.gov (United States)

    Endo, Hironobu; Sekiguchi, Kenji; Shimada, Hitoshi; Ueda, Takehiro; Kowa, Hisatomo; Kanda, Fumio; Toda, Tatsushi

    2018-03-01

    There is no reliable objective indicator for upper motor neuron dysfunction in amyotrophic lateral sclerosis (ALS). To determine the clinical significance and potential utility of magnetic resonance (MR) signals, we investigated the relationship between clinical symptoms and susceptibility changes in the motor cortex measured using susceptibility-weighted MR imaging taken by readily available 3-T MRI in clinical practice. Twenty-four ALS patients and 14 control subjects underwent 3-T MR T1-weighted imaging and susceptibility-weighted MR imaging with the principles of echo-shifting with a train of observations (PRESTO) sequence. We analysed relationships between relative susceptibility changes in the motor cortex assessed using voxel-based analysis (VBA) and clinical scores, including upper motor neuron score, ALS functional rating scale revised score, and Medical Research Council sum score on physical examination. Patients with ALS exhibited significantly lower signal intensity in the precentral gyrus on susceptibility-weighted MR imaging compared with controls. Clinical scores were significantly correlated with susceptibility changes. Importantly, the extent of the susceptibility changes in the bilateral precentral gyri was significantly correlated with upper motor neuron scores. The results of our pilot study using VBA indicated that low signal intensity in motor cortex on susceptibility-weighted MR imaging may correspond to clinical symptoms, particularly upper motor neuron dysfunction. Susceptibility-weighted MR imaging may be a useful diagnostic tool as an objective indicator of upper motor neuron dysfunction.

  10. Tomato susceptibility to root-knot nematodes requires an intact jasmonic Acid signaling pathway

    Science.gov (United States)

    Response of tomato (Solanum lycopersicum) to root-knot nematode (RKN; Meloidogyne spp.) infection was monitored using TOM1 cDNA microarray with resistant (‘Motelle’; Mi-1) and susceptible (‘Moneymaker’; mi) tomato at 24 h after RKN infection. The array analysis identified 1497 genes and 750 genes d...

  11. High School Dropouts: Causes, Consequences, and Cure. Fastback 242.

    Science.gov (United States)

    Grossnickle, Donald R.

    This booklet addresses the issue of high school dropouts. The dropout problem is briefly reviewed and dropout statistics are presented. A section on identifying the dropout lists early warning signs of potential dropouts and examines reasons for dropping out. Seven profiles of dropouts are included which provide personal insights, describe…

  12. Prenatal ethanol exposure increases osteoarthritis susceptibility in female rat offspring by programming a low-functioning IGF-1 signaling pathway

    Science.gov (United States)

    Ni, Qubo; Tan, Yang; Zhang, Xianrong; Luo, Hanwen; Deng, Yu; Magdalou, Jacques; Chen, Liaobin; Wang, Hui

    2015-10-01

    Epidemiological evidence indicates that osteoarthritis (OA) and prenatal ethanol exposure (PEE) are both associated with low birth weight but possible causal interrelationships have not been investigated. To investigate the effects of PEE on the susceptibility to OA in adult rats that experienced intrauterine growth retardation (IUGR), and to explore potential intrauterine mechanisms, we established the rat model of IUGR by PEE and dexamethasone, and the female fetus and 24-week-old adult offspring subjected to strenuous running for 6 weeks were sacrificed. Knee joints were collected from fetuses and adult offspring for histochemistry, immunohistochemistry and qPCR assays. Histological analyses and the Mankin score revealed increased cartilage destruction and accelerated OA progression in adult offspring from the PEE group compared to the control group. Immunohistochemistry showed reduced expression of insulin-like growth factor-1 (IGF-1) signaling pathway components. Furthermore, fetuses in the PEE group experienced IUGR but exhibited a higher postnatal growth rate. The expression of many IGF-1 signaling components was downregulated, which coincided with reduced amounts of type II collagen in the epiphyseal cartilage of fetuses in the PEE group. These results suggest that PEE enhances the susceptibility to OA in female adult rat offspring by down-regulating IGF-1 signaling and retarding articular cartilage development.

  13. Evidence on Dropout Phenomena at Universities

    DEFF Research Database (Denmark)

    Larsen, Malene Rode; Sommersel, Hanna Bjørnøy; Larsen, Michael Søgaard

    This publication is an excerpt from the full technical report ‘Dropout Phenomena at Universities: What is Dropout? Why does Dropout Occur? What Can be Done by the Universities to Prevent or Reduce it? A systematic review’, which was completed in April 2013. The purpose of this excerpt is to present...... the knowledge we have on dropout phenomena at European universities in a short, precise and comprehensible form to allow readers to orient themselves on the subject in a more readable manner....

  14. Dropout Study, 1993-94. Evaluation Report.

    Science.gov (United States)

    Claus, Richard N.; Quimper, Barry E.

    The School District of the City of Saginaw (Michigan) has annually reported on the rate and nature of the dropout population; this dropout report is the fourth edition of the State defined generation of dropout reports. Two hundred twenty-four, or 8% of Saginaw's 2,805 students in grades 9-12, voluntarily terminated their high school education…

  15. High School Dropout and Teen Childbearing

    Science.gov (United States)

    Marcotte, Dave E.

    2013-01-01

    Understanding the relationship between high school dropout and teen childbearing is complicated because both are affected by a variety of difficult to control factors. In this paper, I use panel data on aggregate dropout and fertility rates by age for all fifty states to develop insight by instrumenting for dropout using information on state…

  16. San Diego's High School Dropout Crisis

    Science.gov (United States)

    Wilson, James C.

    2012-01-01

    This article highlights San Diego's dropout problem and how much it's costing the city and the state. Most San Diegans do not realize the enormous impact high school dropouts on their city. The California Dropout Research Project, located at the University of California at Santa Barbara, has estimated the lifetime cost of one class or cohort of…

  17. Primary Education and Dropout in Nepal

    Science.gov (United States)

    Devkota, Shree Prasad; Bagale, Shiba

    2015-01-01

    This article tries to highlight the dropout rate of primary education of Nepal. The main essence of the article is to explore the situation of dropout of primary education. There are several programs and policies to reduce the dropout, out of the school children and so on but still there are several issues that are left behind. Educational budget…

  18. Connecting Dropouts to Career Pathways

    Science.gov (United States)

    Saddler, Sterling; Tyler, Tiffany G.; Maldonado, Cecilia; Cleveland, Roger; Thompson, Lisa K.

    2011-01-01

    There is a critical need to identify solutions to the unemployment of high school dropouts. When a student prematurely leaves school, the economic, social, and political impacts result in negative consequences for the individual and the community. Of the nearly 2.2 million students who drop out of high school every year in the United States,…

  19. Immunization Dropout Rates: Some Issues

    African Journals Online (AJOL)

    vaccination from BCG ‑ Measles first dose has a distinct advantage. DTP1–DTP3 dropout rate measures the ability of the immunization system to reach a child multiple times with the same antigen(s).[3] It also measures the same delivery system multiple times; thereby giving insight into factors that may hinder caregivers to ...

  20. Arabidopsis thaliana resistance to fusarium oxysporum 2 implicates tyrosine-sulfated peptide signaling in susceptibility and resistance to root infection.

    Directory of Open Access Journals (Sweden)

    Yunping Shen

    2013-05-01

    Full Text Available In the plant Arabidopsis thaliana, multiple quantitative trait loci (QTLs, including RFO2, account for the strong resistance of accession Columbia-0 (Col-0 and relative susceptibility of Taynuilt-0 (Ty-0 to the vascular wilt fungus Fusarium oxysporum forma specialis matthioli. We find that RFO2 corresponds to diversity in receptor-like protein (RLP genes. In Col-0, there is a tandem pair of RLP genes: RFO2/At1g17250 confers resistance while RLP2 does not. In Ty-0, the highly diverged RFO2 locus has one RLP gene conferring weaker resistance. While the endogenous RFO2 makes a modest contribution to resistance, transgenic RFO2 provides strong pathogen-specific resistance. The extracellular leucine-rich repeats (eLRRs in RFO2 and RLP2 are interchangeable for resistance and remarkably similar to eLRRs in the receptor-like kinase PSY1R, which perceives tyrosine-sulfated peptide PSY1. Reduced infection in psy1r and mutants of related phytosulfokine (PSK receptor genes PSKR1 and PSKR2 shows that tyrosine-sulfated peptide signaling promotes susceptibility. The related eLRRs in RFO2 and PSY1R are not interchangeable; and expression of the RLP nPcR, in which eLRRs in RFO2 are replaced with eLRRs in PSY1R, results in constitutive resistance. Counterintuitively, PSY1 signaling suppresses nPcR because psy1r nPcR is lethal. The fact that PSK signaling does not similarly affect nPcR argues that PSY1 signaling directly downregulates the expression of nPcR. Our results support a speculative but intriguing model to explain RFO2's role in resistance. We propose that F. oxysporum produces an effector that inhibits the normal negative feedback regulation of PSY1R, which stabilizes PSY1 signaling and induces susceptibility. However, RFO2, acting as a decoy receptor for PSY1R, is also stabilized by the effector and instead induces host immunity. Overall, the quantitative resistance of RFO2 is reminiscent of the better-studied monogenic resistance traits.

  1. Bone quantitative susceptibility mapping using a chemical species-specific R2* signal model with ultrashort and conventional echo data.

    Science.gov (United States)

    Dimov, Alexey V; Liu, Zhe; Spincemaille, Pascal; Prince, Martin R; Du, Jiang; Wang, Yi

    2017-03-05

    To develop quantitative susceptibility mapping (QSM) of bone using an ultrashort echo time (UTE) gradient echo (GRE) sequence for signal acquisition and a bone-specific effective transverse relaxation rate ( R2*) to model water-fat MR signals for field mapping. Three-dimensional radial UTE data (echo times ≥ 40 μs) was acquired on a 3 Tesla scanner and fitted with a bone-specific signal model to map the chemical species and susceptibility field. Experiments were performed ex vivo on a porcine hoof and in vivo on healthy human subjects (n = 7). For water-fat separation, a bone-specific model assigning R2* decay mostly to water was compared with the standard models that assigned the same decay for both fat and water. In the ex vivo experiment, bone QSM was correlated with CT. Compared with standard models, the bone-specific R2* method significantly reduced errors in the fat fraction within the cortical bone in all tested data sets, leading to reduced artifacts in QSM. Good correlation was found between bone CT and QSM values in the porcine hoof (R(2)  = 0.77). Bone QSM was successfully generated in all subjects. The QSM of bone is feasible using UTE with a conventional echo time GRE acquisition and a bone-specific R2* signal model. Magn Reson Med 000:000-000, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  2. Sensory perception of food and insulin-like signals influence seizure susceptibility.

    Directory of Open Access Journals (Sweden)

    Todd R Gruninger

    2008-07-01

    Full Text Available Food deprivation is known to affect physiology and behavior. Changes that occur could be the result of the organism's monitoring of internal and external nutrient availability. In C. elegans, male mating is dependent on food availability; food-deprived males mate with lower efficiency compared to their well-fed counterparts, suggesting that the mating circuit is repressed in low-food environments. This behavioral response could be mediated by sensory neurons exposed to the environment or by internal metabolic cues. We demonstrated that food-deprivation negatively regulates sex-muscle excitability through the activity of chemosensory neurons and insulin-like signaling. Specifically, we found that the repressive effects of food deprivation on the mating circuit can be partially blocked by placing males on inedible food, E. coli that can be sensed but not eaten. We determined that the olfactory AWC neurons actively suppress sex-muscle excitability in response to food deprivation. In addition, we demonstrated that loss of insulin-like receptor (DAF-2 signaling in the sex muscles blocks the ability of food deprivation to suppress the mating circuit. During low-food conditions, we propose that increased activity by specific olfactory neurons (AWCs leads to the release of neuroendocrine signals, including insulin-like ligands. Insulin-like receptor signaling in the sex muscles then reduces cell excitability via activation of downstream molecules, including PLC-gamma and CaMKII.

  3. Work environment and school dropout

    DEFF Research Database (Denmark)

    Hansen, Claus D.; Andersen, Johan Hviid; Lund, Thomas

    Aim The aim of this presentation is to examine the possible impact of work environment (and especially psychosocial work environment) on school dropout. The questions raised are: to what extent do psychosocial work environment and especially the social relations between young apprentices...... and their colleagues and managers play a role in dropping out of upper secondary education? Methods A cohort of 3058 adolescents born in 1989 and a cohort of approximately 2000 young adults born in 1983 are used to examine the associations between work environment and subsequent dropout in upper secondary educational...... indicated that ‘being treated badly by superior’ was part of the reason for doing so. Further analyses show that reporting repetitive and monotonous work tasks increases the risk of dropping out (OR: 1.74) and that reporting bad working climate at ones work place increases the risk of considering...

  4. Basal-subtype and MEK-Pl3K feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

    Energy Technology Data Exchange (ETDEWEB)

    Mirzoeva, Olga K.; Das, Debopriya; Heiser, Laura M.; Bhattacharya, Sanchita; Siwak, Doris; Gendelman, Rina; Bayani, Nora; Wang, Nicholas J.; Neve, Richard M.; Knight, Zachary; Feiler, Heidi S.; Gascard, Philippe; Parvin, Bahram; Spellman, Paul T.; Shokat, Kevan M.; Wyrobek, Andrew J.; Bissell, Mina J.; McCormick, Frank; Kuo, Wen-Lin; Mills, Gordon B.; Gray, Joe W.; Korn, W. Michael

    2009-01-23

    Specific inhibitors of MEK have been developed that efficiently inhibit the oncogenic RAF-MEK-ERK pathway. We employed a systems-based approach to identify breast cancer subtypes particularly susceptible to MEK inhibitors and to understand molecular mechanisms conferring resistance to such compounds. Basal-type breast cancer cells were found to be particularly susceptible to growth-inhibition by small-molecule MEK inhibitors. Activation of the PI3 kinase pathway in response to MEK inhibition through a negative MEK-EGFR-PI3 kinase feedback loop was found to limit efficacy. Interruption of this feedback mechanism by targeting MEK and PI3 kinase produced synergistic effects, including induction of apoptosis and, in some cell lines, cell cycle arrest and protection from apoptosis induced by proapoptotic agents. These findings enhance our understanding of the interconnectivity of oncogenic signal transduction circuits and have implications for the design of future clinical trials of MEK inhibitors in breast cancer by guiding patient selection and suggesting rational combination therapies.

  5. Genetic consequences of habitat fragmentation in plant populations: susceptible signals in plant traits and methodological approaches.

    Science.gov (United States)

    Aguilar, Ramiro; Quesada, Mauricio; Ashworth, Lorena; Herrerias-Diego, Yvonne; Lobo, Jorge

    2008-12-01

    Conservation of genetic diversity, one of the three main forms of biodiversity, is a fundamental concern in conservation biology as it provides the raw material for evolutionary change and thus the potential to adapt to changing environments. By means of meta-analyses, we tested the generality of the hypotheses that habitat fragmentation affects genetic diversity of plant populations and that certain life history and ecological traits of plants can determine differential susceptibility to genetic erosion in fragmented habitats. Additionally, we assessed whether certain methodological approaches used by authors influence the ability to detect fragmentation effects on plant genetic diversity. We found overall large and negative effects of fragmentation on genetic diversity and outcrossing rates but no effects on inbreeding coefficients. Significant increases in inbreeding coefficient in fragmented habitats were only observed in studies analyzing progenies. The mating system and the rarity status of plants explained the highest proportion of variation in the effect sizes among species. The age of the fragment was also decisive in explaining variability among effect sizes: the larger the number of generations elapsed in fragmentation conditions, the larger the negative magnitude of effect sizes on heterozygosity. Our results also suggest that fragmentation is shifting mating patterns towards increased selfing. We conclude that current conservation efforts in fragmented habitats should be focused on common or recently rare species and mainly outcrossing species and outline important issues that need to be addressed in future research on this area.

  6. Two-component signal transduction system SaeRS is involved in competence and penicillin susceptibility in Staphylococcus epidermidis.

    Science.gov (United States)

    Lou, Qiang; Ma, Yuanfang; Qu, Di

    2016-04-01

    Staphylococcus epidermidis, which is a causative pathogen of nosocomial infection, expresses its virulent traits such as biofilm and autolysis regulated by two-component signal transduction system SaeRS. In this study, the S. epidermidis SaeRS was identified to negatively regulate the expression of genes involved in competence (comF, murF), cytolysis (lrgA), and autolysis (lytS) by DNA microarray or real-time RT-PCR analysis. In addition, saeRS mutant showed increased competence and higher susceptibility to antibiotics such as penicillin and oxacillin than the wild-type strain. The study will be helpful for understanding the characterization of the SaeRS in S. epidermidis. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus.

    Science.gov (United States)

    Demirci, F Yesim; Wang, Xingbin; Morris, David L; Feingold, Eleanor; Bernatsky, Sasha; Pineau, Christian; Clarke, Ann; Ramsey-Goldman, Rosalind; Manzi, Susan; Vyse, Timothy J; Kamboh, M I

    2017-06-01

    A major systemic lupus erythematosus (SLE) susceptibility locus lies within a common inversion polymorphism region (encompassing 3.8 - 4.5  Mb) located at 8p23. Initially implicated genes included FAM167A-BLK and XKR6, of which BLK received major attention due to its known role in B-cell biology. Recently, additional SLE risk carried in non-inverted background was also reported. In this case -control study, we further investigated the 'extended' 8p23 locus (~ 4  Mb) where we observed multiple SLE signals and assessed these signals for their relation to the inversion affecting this region. The study involved a North American discovery data set (~ 1200  subjects) and a replication data set (> 10 000  subjects) comprising European-descent individuals. Meta-analysis of 8p23 SNPs, with p data sets, identified 51 genome-wide significant SNPs (p signals (XKR6-FAM167A-BLK subregion), our results also revealed two 'new' SLE signals, including SGK223-CLDN23-MFHAS1 (6.06 × 10-9 ≤ meta p ≤ 4.88 × 10-8) and CTSB (meta p = 4.87 × 10-8) subregions that are located > 2 Mb upstream and ~ 0.3  Mb downstream from previously reported signals. Functional assessment of relevant SNPs indicated putative cis-effects on the expression of various genes at 8p23. Additional analyses in discovery sample, where the inversion genotypes were inferred, replicated the association of non-inverted status with SLE risk and suggested that a number of SLE risk alleles are predominantly carried in non-inverted background. Our results implicate multiple (known+novel) SLE signals/genes at the extended 8p23 locus, beyond previously reported signals/genes, and suggest that this broad locus contributes to SLE risk through the effects of multiple genes/pathways. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Noncognitive Skills, School Achievements and Educational Dropout

    OpenAIRE

    Katja Coneus; Johannes Gernandt; Marianne Saam

    2011-01-01

    We analyse the determinants of dropout from secondary and vocational education in Germany using data on 17- to 21-year-olds from the Socio-Economic Panel from 2000 to 2007. Beyond the role of classical variables like family background and school achievements, we examine the effect of noncognitive skills. At constant school grades, noncognitive skills reduce the risk of becoming an educational dropout. The influence of school achievements on the dropout probability tends to decrease and the in...

  9. Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

    Directory of Open Access Journals (Sweden)

    Shun Lu

    Full Text Available Interferon (IFN signaling has been suggested to play an important role in colorectal carcinogenesis. Our study aimed to examine potentially functional genetic variants in interferon regulatory factor 3 (IRF3, IRF5, IRF7, type I and type II IFN and their receptor genes with respect to colorectal cancer (CRC risk and clinical outcome. Altogether 74 single nucleotide polymorphisms (SNPs were covered by the 34 SNPs genotyped in a hospital-based case-control study of 1327 CRC cases and 758 healthy controls from the Czech Republic. We also analyzed these SNPs in relation to overall survival and event-free survival in a subgroup of 483 patients. Seven SNPs in IFNA1, IFNA13, IFNA21, IFNK, IFNAR1 and IFNGR1 were associated with CRC risk. After multiple testing correction, the associations with the SNPs rs2856968 (IFNAR1 and rs2234711 (IFNGR1 remained formally significant (P = 0.0015 and P<0.0001, respectively. Multivariable survival analyses showed that the SNP rs6475526 (IFNA7/IFNA14 was associated with overall survival of the patients (P = 0.041 and event-free survival among patients without distant metastasis at the time of diagnosis, P = 0.034. The hazard ratios (HRs for rs6475526 remained statistically significant even after adjustment for age, gender, grade and stage (P = 0.029 and P = 0.036, respectively, suggesting that rs6475526 is an independent prognostic marker for CRC. Our data suggest that genetic variation in the IFN signaling pathway genes may play a role in the etiology and survival of CRC and further studies are warranted.

  10. Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

    Science.gov (United States)

    Lu, Shun; Pardini, Barbara; Cheng, Bowang; Naccarati, Alessio; Huhn, Stefanie; Vymetalkova, Veronika; Vodickova, Ludmila; Buchler, Thomas; Hemminki, Kari; Vodicka, Pavel; Försti, Asta

    2014-01-01

    Interferon (IFN) signaling has been suggested to play an important role in colorectal carcinogenesis. Our study aimed to examine potentially functional genetic variants in interferon regulatory factor 3 (IRF3), IRF5, IRF7, type I and type II IFN and their receptor genes with respect to colorectal cancer (CRC) risk and clinical outcome. Altogether 74 single nucleotide polymorphisms (SNPs) were covered by the 34 SNPs genotyped in a hospital-based case-control study of 1327 CRC cases and 758 healthy controls from the Czech Republic. We also analyzed these SNPs in relation to overall survival and event-free survival in a subgroup of 483 patients. Seven SNPs in IFNA1, IFNA13, IFNA21, IFNK, IFNAR1 and IFNGR1 were associated with CRC risk. After multiple testing correction, the associations with the SNPs rs2856968 (IFNAR1) and rs2234711 (IFNGR1) remained formally significant (P = 0.0015 and P<0.0001, respectively). Multivariable survival analyses showed that the SNP rs6475526 (IFNA7/IFNA14) was associated with overall survival of the patients (P = 0.041 and event-free survival among patients without distant metastasis at the time of diagnosis, P = 0.034). The hazard ratios (HRs) for rs6475526 remained statistically significant even after adjustment for age, gender, grade and stage (P = 0.029 and P = 0.036, respectively), suggesting that rs6475526 is an independent prognostic marker for CRC. Our data suggest that genetic variation in the IFN signaling pathway genes may play a role in the etiology and survival of CRC and further studies are warranted.

  11. Factors associated with dropout in medical education: a literature review

    DEFF Research Database (Denmark)

    O'Neill, Lotte Dyhrberg; Wallstedt, Birgitta; Eika, Berit

    2011-01-01

    Medical school dropout may have negative consequences for society, patients, the profession, schools and dropouts. To our knowledge, the literature dealing with dropout from medical school has never been systematically and critically appraised....

  12. Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels.

    Science.gov (United States)

    Ruiz, Henry H; Chi, Tiffany; Shin, Andrew C; Lindtner, Claudia; Hsieh, Wilson; Ehrlich, Michelle; Gandy, Sam; Buettner, Christoph

    2016-08-01

    Epidemiologic studies have demonstrated an association between diabetes and dementia. Insulin signaling within the brain, in particular within the hypothalamus regulates carbohydrate, lipid, and branched chain amino acid (BCAA) metabolism in peripheral organs such as the liver and adipose tissue. We hypothesized that cerebral amyloidosis impairs central nervous system control of metabolism through disruption of insulin signaling in the hypothalamus, which dysregulates glucose and BCAA homeostasis resulting in increased susceptibility to diabetes. We examined whether APP/PS1 mice exhibit increased susceptibility to aging or high-fat diet (HFD)-induced metabolic impairment using metabolic phenotyping and insulin-signaling studies. APP/PS1 mice were more susceptible to high-fat feeding and aging-induced metabolic dysregulation including disrupted BCAA homeostasis and exhibited impaired hypothalamic insulin signaling. Our data suggest that AD pathology increases susceptibility to diabetes due to impaired hypothalamic insulin signaling, and that plasma BCAA levels could serve as a biomarker of hypothalamic insulin action in patients with AD. Copyright © 2016 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

  13. Factors predicting dropout in student nursing assistants

    DEFF Research Database (Denmark)

    Svensson, Annemarie Lyng; Strøyer, Jesper; Ebbehøj, Niels Erik

    2008-01-01

    BACKGROUND: The dropout rate among student nursing assistants (NAs) in Danish health and social care education is high at >20%. AIMS: To explore if recent low back pain (LBP) history is a predictor of dropout among NA students, taking into account conventional risk factors for LBP, general health...

  14. Revisiting Primary School Dropout in Rural Cambodia

    Science.gov (United States)

    No, Fata; Sam, Chanphirun; Hirakawa, Yukiko

    2012-01-01

    Previous studies on school dropout in Cambodia often used data from subjects after they already dropped out or statistics from education-related institutions. Using data from children in two rural provinces before they dropped out, this study examines four main factors in order to identify their influence on primary school dropout in Cambodia.…

  15. Detection of intratumoral susceptibility signals using T2*-weighted gradient echo MRI in patients with clear cell renal cell carcinoma.

    Directory of Open Access Journals (Sweden)

    Shengnan Yu

    Full Text Available OBJECTIVE: To retrospectively evaluate whether T2*-weighted imaging can be used to grade clear cell renal cell carcinomas (ccRCC based on intratumoral susceptibility signals (ISSs. MATERIALS AND METHODS: MR imaging from 37 patients with pathologically-proven ccRCCs was evaluated. ISSs on T2*WI were classified as linear or conglomerated linear structures (type I and dot-like or patchy foci (type II. Two radiologists assessed the likelihood of the presence of ISS, dominant structure of ISS and ratio of ISS area to tumor area. Results were analyzed by nonparametric Mann-Whitney test. RESULTS: ISSs were seen in all patients except for four patients with low-grade ccRCCs and two patients with high-grade ccRCCs. There was no significant difference of the likelihood of the presence of ISS between low- and high-grade ccRCCs. More type I ISSs and less type II ISSs were predictive of low-grade tumors, whereas more conspicuity type II ISSs correlated with higher occurrence of high-grade tumors (P<0.05. The ratio of ISS area to tumor area was also significantly higher for the high-grade group (1.27±0.79 than that for the low-grade group (0.81±0.40 (P<0.05. CONCLUSION: ISSs on T2*-weighted gradient-echo MR images can help grade ccRCCs before operations.

  16. Detection of intratumoral susceptibility signals using T2*-weighted gradient echo MRI in patients with clear cell renal cell carcinoma.

    Science.gov (United States)

    Yu, Shengnan; Qiu, Jianguo; Zhang, Jinggang; Pan, Liang; Xing, Shijun; Zhang, Lijun

    2013-01-01

    To retrospectively evaluate whether T2*-weighted imaging can be used to grade clear cell renal cell carcinomas (ccRCC) based on intratumoral susceptibility signals (ISSs). MR imaging from 37 patients with pathologically-proven ccRCCs was evaluated. ISSs on T2*WI were classified as linear or conglomerated linear structures (type I) and dot-like or patchy foci (type II). Two radiologists assessed the likelihood of the presence of ISS, dominant structure of ISS and ratio of ISS area to tumor area. Results were analyzed by nonparametric Mann-Whitney test. ISSs were seen in all patients except for four patients with low-grade ccRCCs and two patients with high-grade ccRCCs. There was no significant difference of the likelihood of the presence of ISS between low- and high-grade ccRCCs. More type I ISSs and less type II ISSs were predictive of low-grade tumors, whereas more conspicuity type II ISSs correlated with higher occurrence of high-grade tumors (PISSs on T2*-weighted gradient-echo MR images can help grade ccRCCs before operations.

  17. Improving Signal-to-Noise Ratio in Susceptibility Weighted Imaging: A Novel Multicomponent Non-Local Approach.

    Directory of Open Access Journals (Sweden)

    Pasquale Borrelli

    Full Text Available In susceptibility-weighted imaging (SWI, the high resolution required to obtain a proper contrast generation leads to a reduced signal-to-noise ratio (SNR. The application of a denoising filter to produce images with higher SNR and still preserve small structures from excessive blurring is therefore extremely desirable. However, as the distributions of magnitude and phase noise may introduce biases during image restoration, the application of a denoising filter is non-trivial. Taking advantage of the potential multispectral nature of MR images, a multicomponent approach using a Non-Local Means (MNLM denoising filter may perform better than a component-by-component image restoration method. Here we present a new MNLM-based method (Multicomponent-Imaginary-Real-SWI, hereafter MIR-SWI to produce SWI images with high SNR and improved conspicuity. Both qualitative and quantitative comparisons of MIR-SWI with the original SWI scheme and previously proposed SWI restoring pipelines showed that MIR-SWI fared consistently better than the other approaches. Noise removal with MIR-SWI also provided improvement in contrast-to-noise ratio (CNR and vessel conspicuity at higher factors of phase mask multiplications than the one suggested in the literature for SWI vessel imaging. We conclude that a proper handling of noise in the complex MR dataset may lead to improved image quality for SWI data.

  18. Predicting Psychotherapy Dropouts: A Multilevel Approach.

    Science.gov (United States)

    Kegel, Alexander F; Flückiger, Christoph

    2015-01-01

    The role of therapeutic processes in predicting premature termination of psychotherapy has been a particular focus of recent research. The purpose of this study was to contrast outpatients who completed therapy and those who dropped out with respect to their self-reported in-session experiences of self-esteem, mastery, clarification and the therapeutic alliance. The 296 patients with mixed disorders were treated with an integrative form of cognitive-behavioural therapy without pre-determined time limit (M = 20.2 sessions). Multilevel analyses indicated that patients who did not completetreatment reported, on average, lower levels of self-esteem, mastery and clarification and lower ratings of their therapeutic alliance in treatment in contrast to patients who completed therapy. Patient-reported change in self-esteem experiences over the course of treatment turned out to be the strongest predictor of dropout from psychotherapy or successful completion. When dropout occurred before the average treatment length was reached, patients reported fewer clarifying experiences as early as the first session and their ratings of the therapeutic alliance were characterized by an absence of positive development. Both of these aspects seem to be involved in patients' decisions to leave treatment early. The findings underscore the importance of the therapeutic process in understanding the mechanisms behind treatment dropout. Analyses data from 296 patients at a private outpatient clinic in a routine practice setting (CBT). Completer/dropout definition: presence or absence of measurement battery at post-assessment. Focuses on change in therapy processes by investigating post-session reports. Finds that positive changes in self-esteem experiences is the most robust predictor of dropout, followed by ratings of clarification experiences and the global alliance. In line with recent dropout research, these process indicators might help to detect therapeutic situations that are

  19. The reasons of dropout of sport in Hong Kong school athletes

    OpenAIRE

    Hassan, Abdul-Rahman; Lam, Michael Huen Sum; Ku, Susanna; Li, William Ho Cheung; Lee, Ka Yiu; Ho, Eva; Flint, Stuart W.; Wong, Anthony Siu Wo

    2017-01-01

    Dropout of sport is an issue in sport and public health domains. The aim of this study was to identify the potential dropout reasons of school athletes and to examine if their perception of dropout was affected by the previous dropout experience. There were 50 subjects who were divided into two groups based on their previous dropout experience (Dropout Group=22, No Dropout Group=28). They filled a questionnaire about potential dropout reasons of the current sport. Coach and teammates were two...

  20. Involvement of salicylic acid, ethylene and jasmonic acid signalling pathways in the susceptibility of tomato to Fusarium oxysporum

    NARCIS (Netherlands)

    Di, X.; Gomila, J.; Takken, F.L.W.

    Phytohormones, such as salicylic acid (SA), ethylene (ET) and jasmonic acid (JA), play key roles in plant defence following pathogen attack. The involvement of these hormones in susceptibility following Fusarium oxysporum (Fo) infection has mostly been studied in Arabidopsis thaliana. However, Fo

  1. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

    DEFF Research Database (Denmark)

    Amin Al Olama, Ali; Dadaev, Tokhir; Hazelett, Dennis J

    2015-01-01

    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancest...

  2. Jasmonate signalling drives time-of-day differences in susceptibility of Arabidopsis to the fungal pathogen Botrytis cinerea

    NARCIS (Netherlands)

    Ingle, R.A.; Stoker, C.; Stone, W.; Adams, N.; Smith, R.W.; Grant, M.; Carré, I.; Roden, L.C.; Denby, K.J.

    2015-01-01

    The circadian clock, an internal timekeeping mechanism, allows plants to anticipate regular changes in the environment, such as light and dark, and biotic challenges such as pathogens and herbivores. Here, we demonstrate that the plant circadian clock influences susceptibility to the necrotrophic

  3. Puertorriquenos En Chicago: El Problema Educativo Del Dropout

    Science.gov (United States)

    Lucas, Isidro

    1974-01-01

    Article written in Spanish. Defines the term "dropout," discusses the characteristics and motivations of Puerto Rican school dropouts in Chicago, and outlines the problems in educating them. (Author/RJ)

  4. The Annual Dropout Report 1986-87. OEA Evaluation Report.

    Science.gov (United States)

    Collins, Carla; Gampert, Richard

    Examination of dropout trends in New York City for 1986-87 reveals the following: (1) the annual dropout rate was 7.3 percent for the high schools, and 8.3 percent system-wide; (2) the estimated four-year dropout rate was 26.3 percent for the high schools, and 29.2 percent system-wide; (3) the 1986-87 four-year high school dropout rate was 6.2…

  5. Construction and validation of students' dropout scale | Fehintola ...

    African Journals Online (AJOL)

    This study constructed and validated a measure for students' dropout from secondary school programme. The Students' Dropout Scale (SDS) is a 25-items instrument developed according to the frame work of the social sciences literature on concepts of dropout. Descriptive survey research design was employed.

  6. Adjustment of High School Dropouts in Closed Religious Communities

    Science.gov (United States)

    Itzhaki, Yael; Itzhaky, Haya; Yablon, Yaacov B.

    2018-01-01

    Background: While extensive research has been done on high-school dropouts' adjustment, there is little data on dropouts from closed religious communities. Objective: This study examines the contribution of personal and social resources to the adjustment of high school dropouts in Ultraorthodox Jewish communities in Israel. Method: Using a…

  7. Oregon's High School Dropouts: Examining the Economic and Social Costs

    Science.gov (United States)

    House, Emily Anne

    2010-01-01

    This analysis presents the public costs of high school dropouts in Oregon. It examines how dropouts in the state dramatically impact state finances through reduced tax revenues, increased Medicaid costs, and high incarceration rates. This study describes how much high school dropouts cost Oregon's tax-payers each year, and how much could be saved…

  8. Do Employment Subsidies Reduce Early Apprenticeship Dropout?

    Science.gov (United States)

    Fries, Jan; Göbel, Christian; Maier, Michael F.

    2014-01-01

    We evaluate the effect of the Apprenticeship Bonus, an employment subsidy programme, on early apprenticeship dropout. Eligibility for the programme is restricted to school leavers who have actively looked for an apprenticeship to start immediately after leaving school, but were unsuccessful in finding one. Our analysis is based on rich survey data…

  9. Utah Drop-Out Drug Use Questionnaire.

    Science.gov (United States)

    Governor's Citizen Advisory Committee on Drugs, Salt Lake City, UT.

    This questionnaire assesses drug use practices in high school drop-outs. The 79 items (multiple choice or apply/not apply) are concerned with demographic data and use, use history, reasons for use/nonuse, attitudes toward drugs, availability of drugs, and drug information with respect to narcotics, amphetamines, LSD, Marijuana, and barbiturates.…

  10. Parental Background and University Dropout in Italy

    Science.gov (United States)

    Aina, Carmen

    2013-01-01

    Using longitudinal data drawn from the European Community Household Panel, this paper examines Italian university entry and dropout rates in the context of specific parental and family characteristics. We are interested in the effects of the household's cultural and financial conditions on shaping investment in tertiary education and its failure,…

  11. Dropout Prevention: An EPI Research Brief

    Science.gov (United States)

    Johnston, J. Howard

    2010-01-01

    Tons of paper and thousands of gallons of ink, not to mention countless digits and bytes, have been devoted to the study of dropouts--much of it focused on the causes of dropping out of school and the complex factors that contribute to that decision. Despite the intensity of this investigation, little has changed, except that the consequences of…

  12. Causes of Student Absenteeism and School Dropouts

    Science.gov (United States)

    Sahin, Seyma; Arseven, Zeynep; Kiliç, Abdurrahman

    2016-01-01

    The aim of the study is to investigate the causes of student absenteeism and school dropouts at primary, secondary and high school level in Düzce Province and to develop suggestions for solving these problems. A "case study" design, which is one of the qualitative research approaches, was used in this study. The study group consisted of…

  13. Predicting secondary school dropout among South African ...

    African Journals Online (AJOL)

    Education is one of the strongest predictors of health worldwide. In South Africa, school dropout is a crisis where by Grade 12, only 52% of the age appropriate population remain enrolled. Survival analysis was used to identify the risk of dropping out of secondary school for male and female adolescents and examine the ...

  14. High School Dropout: The Students' Perspective

    National Research Council Canada - National Science Library

    Francesca Salvà-Mut; Miquel F Oliver-Trobat; Rubén Comas-Forgas

    2014-01-01

      This study addresses the problem of high school dropout in Spain. It aims to gain a more profound understanding of the reasons and processes that lead to students leaving school, based on the point of view of the teenagers themselves...

  15. Selected determinants may account for dropout risks among medical students

    DEFF Research Database (Denmark)

    Mørcke, Anne Mette; O'Neill, Lotte; Kjeldsen, Inge Trads

    2012-01-01

    INTRODUCTION: The dropout level from the Danish medical schools is high, but we have only little insight into this problem. The purpose of this study was to qualify the ongoing discussions concerning dropout. MATERIAL AND METHODS: In this retrospective cohort study, relevant variables were....... CONCLUSION: The dropout rate has been decreasing during the past decade. Young people considering studying medicine could be advised to choose natural science subjects in high school, and a number of research questions concerning preparedness for medical school are worth pursuing. Leave or very low grades...... during their first year. The type of admission exam was a strong predictor of dropout in the pre-admission model, whereas previous higher education protected against dropout. Obtaining leave was a very strong predictor of dropout in the post-admission model, whereas high grades protected against dropout...

  16. Learning Analytics focused on student behavior. Case study: dropout in distance learning institutions

    Directory of Open Access Journals (Sweden)

    Jose Aguilar

    2017-04-01

    Full Text Available Normally, Learning Analytics (LA can be focused on the analysis of the learning process or the student behavior. In this paper is analyzed the use of LA in the context of distance learning universities, particularly focuses on the students’ behavior. We propose to use a new concept, called "Autonomic Cycle of Learning Analysis Tasks", which defines a set of tasks of LA, whose common objective is to achieve an improvement in the process under study. In this paper, we develop the "Autonomic Cycle of LA Tasks" to analyze the dropout in distance learning institutions. We use a business intelligence methodology in order to develop the "Autonomic Cycle of LA Tasks" for the analysis of the dropout in distance learning. The Autonomic Cycle identifies factors that influence the decision of a student to abandon their studies, predicts the potentially susceptible students to abandon their university studies, and define a motivational pattern for these students.

  17. Effect of activation of canonical Wnt signaling by the Wnt-3a protein on the susceptibility of PC12 cells to oxidative and apoptotic insults

    Directory of Open Access Journals (Sweden)

    E.M. Kawamoto

    2012-01-01

    Full Text Available Wnt proteins are involved in tissue development and their signaling pathways play an important role during embryogenesis. Wnt signaling can promote cell survival, which is beneficial for neurons, but could also lead to tumor development in different tissues. The present study investigated the effects of a Wnt protein on the susceptibility of a neural tumor cell line (PC12 cells to the cytotoxic compounds ferrous sulfate (10 mM, staurosporine (100 and 500 nM, 3-nitropropionic acid (5 mM, and amyloid β-peptide (Aβ25-35; 50 µM. Cells (1 x 10(6 cells/mL were treated with the Wnt-3a recombinant peptide (200 ng/mL for 24 h before exposure to toxic insults. The Wnt-3a protein partially protected PC12 cells, with a 6-15% increase in cell viability in the presence of toxic agents, similar to the effect measured using the MTT and lactate dehydrogenase cell viability assays. The Wnt-3a protein increased protein expression of β-catenin by 52% compared to control. These findings suggest that Wnt signaling can protect neural cells against apoptosis induced by toxic agents, which are relevant to the pathogenesis of Alzheimer’s and Huntington’s diseases.

  18. Effect of activation of canonical Wnt signaling by the Wnt-3a protein on the susceptibility of PC12 cells to oxidative and apoptotic insults

    Energy Technology Data Exchange (ETDEWEB)

    Kawamoto, E.M. [Departamento de Farmacologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP (Brazil); Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD (United States); Gleichmann, M. [Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD (United States); Yshii, L.M.; Sá Lima, L. de [Departamento de Farmacologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP (Brazil); Mattson, M.P. [Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD (United States); Scavone, C. [Departamento de Farmacologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP (Brazil)

    2011-11-25

    Wnt proteins are involved in tissue development and their signaling pathways play an important role during embryogenesis. Wnt signaling can promote cell survival, which is beneficial for neurons, but could also lead to tumor development in different tissues. The present study investigated the effects of a Wnt protein on the susceptibility of a neural tumor cell line (PC12 cells) to the cytotoxic compounds ferrous sulfate (10 mM), staurosporine (100 and 500 nM), 3-nitropropionic acid (5 mM), and amyloid β-peptide (Aβ{sub 25-35}; 50 µM). Cells (1 × 10{sup 6} cells/mL) were treated with the Wnt-3a recombinant peptide (200 ng/mL) for 24 h before exposure to toxic insults. The Wnt-3a protein partially protected PC12 cells, with a 6-15% increase in cell viability in the presence of toxic agents, similar to the effect measured using the MTT and lactate dehydrogenase cell viability assays. The Wnt-3a protein increased protein expression of β-catenin by 52% compared to control. These findings suggest that Wnt signaling can protect neural cells against apoptosis induced by toxic agents, which are relevant to the pathogenesis of Alzheimer's and Huntington's diseases.

  19. Effect of genetic variation in microRNA binding site in WNT1-inducible signaling pathway protein 1 gene on oral squamous cell carcinoma susceptibility.

    Directory of Open Access Journals (Sweden)

    Hon-Kit Lau

    Full Text Available Oral squamous cell carcinoma (OSCC, which is the most common head and neck cancer, accounts for 1%-2% of all human malignancies and is characterized by poor prognosis and reduced survival rates. WNT1-inducible signaling pathway protein 1 (WISP1, a cysteine-rich protein belonging to the Cyr61, CTGF, Nov (CCN family of matricellular proteins, has many developmental functions and may be involved in carcinogenesis. This study investigated WISP1 single-nucleotide polymorphisms (SNPs to elucidate OSCC susceptibility and clinicopathologic characteristics.Real-time polymerase chain reaction was used to analyze 6 SNPs of WISP1 in 900 OSCC patients and 1200 cancer-free controls. The results showed that WISP1 rs2929970 polymorphism carriers with at least one G allele were susceptible to OSCC. Moreover, compared with smokers, non-smoker patients with higher frequencies of WISP1 rs2929970 (AG + GG variants had a late stage (stages III and IV and a large tumor size. In addition, OSCC patients who were betel quid chewers and carried WISP1 rs16893344 (CT + TT variants had a low risk of lymph node metastasis.Our results demonstrate that a joint effect of WISP1 rs2929970 with smoking as well as WISP1 rs16893344 with betel nut chewing causally contributes to the occurrence of OSCC. WISP1 polymorphism may serve as a marker or a therapeutic target in OSCC.

  20. Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia

    Directory of Open Access Journals (Sweden)

    McGinnis Ralph

    2007-06-01

    Full Text Available Abstract Background Evidence of genetic association between the NRG1 (Neuregulin-1 gene and schizophrenia is now well-documented. Furthermore, several recent reports suggest association between schizophrenia and single-nucleotide polymorphisms (SNPs in ERBB4, one of the receptors for Neuregulin-1. In this study, we have extended the previously published associations by investigating the involvement of all eight genes from the ERBB and NRG families for association with schizophrenia. Methods Eight genes from the ERBB and NRG families were tested for association to schizophrenia using a collection of 396 cases and 1,342 blood bank controls ascertained from Aberdeen, UK. A total of 365 SNPs were tested. Association testing of both alleles and genotypes was carried out using the fast Fisher's Exact Test (FET. To understand better the nature of the associations, all pairs of SNPs separated by ≥ 0.5 cM with at least nominal evidence of association (P Results 42 out of 365 tested SNPs in the eight genes from the ERBB and NRG gene families were significantly associated with schizophrenia (P Conclusion These new findings suggest that observed associations between NRG1 and schizophrenia may be mediated through functional interaction not just with ERBB4, but with other members of the NRG and ERBB families. There is evidence that genetic interaction among these loci may increase susceptibility to schizophrenia.

  1. Ski overexpression in skeletal muscle modulates genetic programs that control susceptibility to diet-induced obesity and insulin signaling.

    Science.gov (United States)

    Diaz, Marianne; Martel, Nick; Fitzsimmons, Rebecca L; Eriksson, Natalie A; Cowin, Gary J; Thomas, Gethin P; Cao, Kim-Anh Lê; Muscat, George E O; Leong, Gary M

    2012-11-01

    Transgenic mice overexpressing chicken Ski (c-Ski) have marked decrease in adipose mass with skeletal muscle hypertrophy. Recent evidence indicates a role for c-Ski in lipogenesis and energy expenditure. In the present study, wild type (WT) and c-Ski mice were challenged on a high-fat (HF) diet to determine whether c-Ski mice were resistant to diet-induced obesity. During the HF feeding WT mice gained significantly more weight than chow-fed animals, while c-Ski mice were partially resistant to the effects of the HF diet on weight. Body composition analysis confirmed the decreased adipose mass in c-Ski mice compared to WT mice. c-Ski mice possess a similar metabolic rate and level of food consumption to WT littermates, despite lower activity levels and on chow diet show mild glucose intolerance relative to WT littermates. On HF diet, glucose tolerance surprisingly remained unchanged in c-Ski mice, while it became worse in WT mice. Skeletal muscle of c-Ski mice exhibit impaired insulin-stimulated Akt phosphorylation and glucose uptake. In concordance, gene expression profiling of skeletal muscle of chow and HF-fed mice indicated that Ski suppresses gene expression associated with insulin signaling and glucose uptake and alters gene pathways involved in myogenesis and adipogenesis. In conclusion, c-Ski mice are partially resistant to diet-induced obesity and display aberrant insulin signaling and glucose homeostasis which is associated with alterations in gene expression that inhibit lipogenesis and insulin signaling. These results suggest Ski plays a major role in skeletal muscle metabolism and adipogenesis and hence influences risk of obesity and diabetes.

  2. Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.

    Science.gov (United States)

    Chirieleison, Steven M; Marsh, Rebecca A; Kumar, Prathna; Rathkey, Joseph K; Dubyak, George R; Abbott, Derek W

    2017-06-09

    The X-linked inhibitor of apoptosis (XIAP) protein has been identified as a key genetic driver of two distinct inflammatory disorders, X-linked lymphoproliferative syndrome 2 (XLP-2) and very-early-onset inflammatory bowel disease (VEO-IBD). Molecularly, the role of XIAP mutations in the pathogenesis of these disorders is unclear. Recent work has consistently shown XIAP to be critical for signaling downstream of the Crohn's disease susceptibility protein nucleotide-binding oligomerization domain-containing 2 (NOD2); however, the reported effects of XLP-2 and VEO-IBD XIAP mutations on cell death have been inconsistent. In this manuscript, we describe a CRISPR-mediated genetic system for cells of the myeloid lineage in which XIAP alleles can be replaced with disease-associated XIAP variants expressed at endogenous levels to simultaneously study inflammation-related cell death and NOD2 signaling. We show that, consistent with previous studies, NOD2 signaling is critically dependent on the BIR2 domain of XIAP. We further used this system to reconcile the aforementioned inconsistent XIAP cell death data to show that XLP-2 and VEO-IBD XIAP mutations that exhibit a loss-of-function NOD2 phenotype also lower the threshold for inflammatory cell death. Last, we identified and studied three novel patient XIAP mutations and used this system to characterize NOD2 and cell death phenotypes driven by XIAP. The results of this work support the role of XIAP in mediating NOD2 signaling while reconciling the role of XLP-2 and VEO-IBD XIAP mutations in inflammatory cell death and provide a set of tools and framework to rapidly test newly discovered XIAP variants. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. High School Dropout Experiences: A Social Capital Perspective

    OpenAIRE

    Drewry, Julie Anne

    2007-01-01

    The purpose of this study was to record and analyze students' experiences with dropping out of high school within a social capital framework. Discussing the stories of high school dropouts provided valuable information related to the root causes of dropout behaviors in a social capital context. This information can be used to develop programs designed to increase social capital in schools, families, and communities, which can contribute to a decrease in dropout behaviors. This phenomenol...

  4. Noncognitive Skills, School Achievements and Educational Dropout (Revised Version)

    OpenAIRE

    Coneus, Katja; Gernandt, Johannes; Saam, Marianne

    2010-01-01

    We analyse the determinants of dropout from secondary and vocational education in Germany using data from the Socio-Economic Panel from 2000 to 2007. In addition to the role of classical variables like family background and school achievements, we examine the effect of noncognitive skills. Both, better school grades and higher noncognitive skills reduce the risk of becoming an educational dropout. The influence of school achievements on the dropout probability tends to decrease and the influe...

  5. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

    Science.gov (United States)

    Day, Felix R; Ruth, Katherine S; Thompson, Deborah J; Lunetta, Kathryn L; Pervjakova, Natalia; Chasman, Daniel I; Stolk, Lisette; Finucane, Hilary K; Sulem, Patrick; Bulik-Sullivan, Brendan; Esko, Tõnu; Johnson, Andrew D; Elks, Cathy E; Franceschini, Nora; He, Chunyan; Altmaier, Elisabeth; Brody, Jennifer A; Franke, Lude L; Huffman, Jennifer E; Keller, Margaux F; McArdle, Patrick F; Nutile, Teresa; Porcu, Eleonora; Robino, Antonietta; Rose, Lynda M; Schick, Ursula M; Smith, Jennifer A; Teumer, Alexander; Traglia, Michela; Vuckovic, Dragana; Yao, Jie; Zhao, Wei; Albrecht, Eva; Amin, Najaf; Corre, Tanguy; Hottenga, Jouke-Jan; Mangino, Massimo; Smith, Albert V; Tanaka, Toshiko; Abecasis, Goncalo; Andrulis, Irene L; Anton-Culver, Hoda; Antoniou, Antonis C; Arndt, Volker; Arnold, Alice M; Barbieri, Caterina; Beckmann, Matthias W; Beeghly-Fadiel, Alicia; Benitez, Javier; Bernstein, Leslie; Bielinski, Suzette J; Blomqvist, Carl; Boerwinkle, Eric; Bogdanova, Natalia V; Bojesen, Stig E; Bolla, Manjeet K; Borresen-Dale, Anne-Lise; Boutin, Thibaud S; Brauch, Hiltrud; Brenner, Hermann; Brüning, Thomas; Burwinkel, Barbara; Campbell, Archie; Campbell, Harry; Chanock, Stephen J; Chapman, J Ross; Chen, Yii-Der Ida; Chenevix-Trench, Georgia; Couch, Fergus J; Coviello, Andrea D; Cox, Angela; Czene, Kamila; Darabi, Hatef; De Vivo, Immaculata; Demerath, Ellen W; Dennis, Joe; Devilee, Peter; Dörk, Thilo; Dos-Santos-Silva, Isabel; Dunning, Alison M; Eicher, John D; Fasching, Peter A; Faul, Jessica D; Figueroa, Jonine; Flesch-Janys, Dieter; Gandin, Ilaria; Garcia, Melissa E; García-Closas, Montserrat; Giles, Graham G; Girotto, Giorgia G; Goldberg, Mark S; González-Neira, Anna; Goodarzi, Mark O; Grove, Megan L; Gudbjartsson, Daniel F; Guénel, Pascal; Guo, Xiuqing; Haiman, Christopher A; Hall, Per; Hamann, Ute; Henderson, Brian E; Hocking, Lynne J; Hofman, Albert; Homuth, Georg; Hooning, Maartje J; Hopper, John L; Hu, Frank B; Huang, Jinyan; Humphreys, Keith; Hunter, David J; Jakubowska, Anna; Jones, Samuel E; Kabisch, Maria; Karasik, David; Knight, Julia A; Kolcic, Ivana; Kooperberg, Charles; Kosma, Veli-Matti; Kriebel, Jennifer; Kristensen, Vessela; Lambrechts, Diether; Langenberg, Claudia; Li, Jingmei; Li, Xin; Lindström, Sara; Liu, Yongmei; Luan, Jian'an; Lubinski, Jan; Mägi, Reedik; Mannermaa, Arto; Manz, Judith; Margolin, Sara; Marten, Jonathan; Martin, Nicholas G; Masciullo, Corrado; Meindl, Alfons; Michailidou, Kyriaki; Mihailov, Evelin; Milani, Lili; Milne, Roger L; Müller-Nurasyid, Martina; Nalls, Michael; Neale, Ben M; Nevanlinna, Heli; Neven, Patrick; Newman, Anne B; Nordestgaard, Børge G; Olson, Janet E; Padmanabhan, Sandosh; Peterlongo, Paolo; Peters, Ulrike; Petersmann, Astrid; Peto, Julian; Pharoah, Paul D P; Pirastu, Nicola N; Pirie, Ailith; Pistis, Giorgio; Polasek, Ozren; Porteous, David; Psaty, Bruce M; Pylkäs, Katri; Radice, Paolo; Raffel, Leslie J; Rivadeneira, Fernando; Rudan, Igor; Rudolph, Anja; Ruggiero, Daniela; Sala, Cinzia F; Sanna, Serena; Sawyer, Elinor J; Schlessinger, David; Schmidt, Marjanka K; Schmidt, Frank; Schmutzler, Rita K; Schoemaker, Minouk J; Scott, Robert A; Seynaeve, Caroline M; Simard, Jacques; Sorice, Rossella; Southey, Melissa C; Stöckl, Doris; Strauch, Konstantin; Swerdlow, Anthony; Taylor, Kent D; Thorsteinsdottir, Unnur; Toland, Amanda E; Tomlinson, Ian; Truong, Thérèse; Tryggvadottir, Laufey; Turner, Stephen T; Vozzi, Diego; Wang, Qin; Wellons, Melissa; Willemsen, Gonneke; Wilson, James F; Winqvist, Robert; Wolffenbuttel, Bruce B H R; Wright, Alan F; Yannoukakos, Drakoulis; Zemunik, Tatijana; Zheng, Wei; Zygmunt, Marek; Bergmann, Sven; Boomsma, Dorret I; Buring, Julie E; Ferrucci, Luigi; Montgomery, Grant W; Gudnason, Vilmundur; Spector, Tim D; van Duijn, Cornelia M; Alizadeh, Behrooz Z; Ciullo, Marina; Crisponi, Laura; Easton, Douglas F; Gasparini, Paolo P; Gieger, Christian; Harris, Tamara B; Hayward, Caroline; Kardia, Sharon L R; Kraft, Peter; McKnight, Barbara; Metspalu, Andres; Morrison, Alanna C; Reiner, Alex P; Ridker, Paul M; Rotter, Jerome I; Toniolo, Daniela; Uitterlinden, André G; Ulivi, Sheila; Völzke, Henry; Wareham, Nicholas J; Weir, David R; Yerges-Armstrong, Laura M; Price, Alkes L; Stefansson, Kari; Visser, Jenny A; Ong, Ken K; Chang-Claude, Jenny; Murabito, Joanne M; Perry, John R B; Murray, Anna

    2015-11-01

    Menopause timing has a substantial impact on infertility and risk of disease, including breast cancer, but the underlying mechanisms are poorly understood. We report a dual strategy in ∼70,000 women to identify common and low-frequency protein-coding variation associated with age at natural menopause (ANM). We identified 44 regions with common variants, including two regions harboring additional rare missense alleles of large effect. We found enrichment of signals in or near genes involved in delayed puberty, highlighting the first molecular links between the onset and end of reproductive lifespan. Pathway analyses identified major association with DNA damage response (DDR) genes, including the first common coding variant in BRCA1 associated with any complex trait. Mendelian randomization analyses supported a causal effect of later ANM on breast cancer risk (∼6% increase in risk per year; P = 3 × 10(-14)), likely mediated by prolonged sex hormone exposure rather than DDR mechanisms.

  6. Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Science.gov (United States)

    Lunetta, Kathryn L.; Pervjakova, Natalia; Chasman, Daniel I.; Stolk, Lisette; Finucane, Hilary K.; Sulem, Patrick; Bulik-Sullivan, Brendan; Esko, Tõnu; Johnson, Andrew D.; Elks, Cathy E.; Franceschini, Nora; He, Chunyan; Altmaier, Elisabeth; Brody, Jennifer A.; Franke, Lude L.; Huffman, Jennifer E.; Keller, Margaux F.; McArdle, Patrick F.; Nutile, Teresa; Porcu, Eleonora; Robino, Antonietta; Rose, Lynda M.; Schick, Ursula M.; Smith, Jennifer A.; Teumer, Alexander; Traglia, Michela; Vuckovic, Dragana; Yao, Jie; Zhao, Wei; Albrecht, Eva; Amin, Najaf; Corre, Tanguy; Hottenga, Jouke-Jan; Mangino, Massimo; Smith, Albert V.; Tanaka, Toshiko; Abecasis, Goncalo; Andrulis, Irene L.; Anton-Culver, Hoda; Antoniou, Antonis C.; Arndt, Volker; Arnold, Alice M.; Barbieri, Caterina; Beckmann, Matthias W.; Beeghly-Fadiel, Alicia; Benitez, Javier; Bernstein, Leslie; Bielinski, Suzette J.; Blomqvist, Carl; Boerwinkle, Eric; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; Borresen-Dale, Anne-Lise; Boutin, Thibaud S; Brauch, Hiltrud; Brenner, Hermann; Brüning, Thomas; Burwinkel, Barbara; Campbell, Archie; Campbell, Harry; Chanock, Stephen J.; Chapman, J. Ross; Chen, Yii-Der Ida; Chenevix-Trench, Georgia; Couch, Fergus J.; Coviello, Andrea D.; Cox, Angela; Czene, Kamila; Darabi, Hatef; De Vivo, Immaculata; Demerath, Ellen W.; Dennis, Joe; Devilee, Peter; Dörk, Thilo; dos-Santos-Silva, Isabel; Dunning, Alison M.; Eicher, John D.; Fasching, Peter A.; Faul, Jessica D.; Figueroa, Jonine; Flesch-Janys, Dieter; Gandin, Ilaria; Garcia, Melissa E.; García-Closas, Montserrat; Giles, Graham G.; Girotto, Giorgia G.; Goldberg, Mark S.; González-Neira, Anna; Goodarzi, Mark O.; Grove, Megan L.; Gudbjartsson, Daniel F.; Guénel, Pascal; Guo, Xiuqing; Haiman, Christopher A.; Hall, Per; Hamann, Ute; Henderson, Brian E.; Hocking, Lynne J.; Hofman, Albert; Homuth, Georg; Hooning, Maartje J.; Hopper, John L.; Hu, Frank B.; Huang, Jinyan; Humphreys, Keith; Hunter, David J.; Jakubowska, Anna; Jones, Samuel E.; Kabisch, Maria; Karasik, David; Knight, Julia A.; Kolcic, Ivana; Kooperberg, Charles; Kosma, Veli-Matti; Kriebel, Jennifer; Kristensen, Vessela; Lambrechts, Diether; Langenberg, Claudia; Li, Jingmei; Li, Xin; Lindström, Sara; Liu, Yongmei; Luan, Jian’an; Lubinski, Jan; Mägi, Reedik; Mannermaa, Arto; Manz, Judith; Margolin, Sara; Marten, Jonathan; Martin, Nicholas G.; Masciullo, Corrado; Meindl, Alfons; Michailidou, Kyriaki; Mihailov, Evelin; Milani, Lili; Milne, Roger L.; Müller-Nurasyid, Martina; Nalls, Michael; Neale, Ben M.; Nevanlinna, Heli; Neven, Patrick; Newman, Anne B.; Nordestgaard, Børge G.; Olson, Janet E.; Padmanabhan, Sandosh; Peterlongo, Paolo; Peters, Ulrike; Petersmann, Astrid; Peto, Julian; Pharoah, Paul D.P.; Pirastu, Nicola N.; Pirie, Ailith; Pistis, Giorgio; Polasek, Ozren; Porteous, David; Psaty, Bruce M.; Pylkäs, Katri; Radice, Paolo; Raffel, Leslie J.; Rivadeneira, Fernando; Rudan, Igor; Rudolph, Anja; Ruggiero, Daniela; Sala, Cinzia F.; Sanna, Serena; Sawyer, Elinor J.; Schlessinger, David; Schmidt, Marjanka K.; Schmidt, Frank; Schmutzler, Rita K.; Schoemaker, Minouk J.; Scott, Robert A.; Seynaeve, Caroline M.; Simard, Jacques; Sorice, Rossella; Southey, Melissa C.; Stöckl, Doris; Strauch, Konstantin; Swerdlow, Anthony; Taylor, Kent D.; Thorsteinsdottir, Unnur; Toland, Amanda E.; Tomlinson, Ian; Truong, Thérèse; Tryggvadottir, Laufey; Turner, Stephen T.; Vozzi, Diego; Wang, Qin; Wellons, Melissa; Willemsen, Gonneke; Wilson, James F.; Winqvist, Robert; Wolffenbuttel, Bruce B.H.R.; Wright, Alan F.; Yannoukakos, Drakoulis; Zemunik, Tatijana; Zheng, Wei; Zygmunt, Marek; Bergmann, Sven; Boomsma, Dorret I.; Buring, Julie E.; Ferrucci, Luigi; Montgomery, Grant W.; Gudnason, Vilmundur; Spector, Tim D.; van Duijn, Cornelia M; Alizadeh, Behrooz Z.; Ciullo, Marina; Crisponi, Laura; Easton, Douglas F.; Gasparini, Paolo P.; Gieger, Christian; Harris, Tamara B.; Hayward, Caroline; Kardia, Sharon L.R.; Kraft, Peter; McKnight, Barbara; Metspalu, Andres; Morrison, Alanna C.; Reiner, Alex P.; Ridker, Paul M.; Rotter, Jerome I.; Toniolo, Daniela; Uitterlinden, André G.; Ulivi, Sheila; Völzke, Henry; Wareham, Nicholas J.; Weir, David R.; Yerges-Armstrong, Laura M.; Price, Alkes L.; Stefansson, Kari; Visser, Jenny A.; Ong, Ken K.; Chang-Claude, Jenny; Murabito, Joanne M.; Perry, John R.B.; Murray, Anna

    2015-01-01

    Menopause timing has a substantial impact on infertility and risk of disease, including breast cancer, but the underlying mechanisms are poorly understood. We report a dual strategy in ~70,000 women to identify common and low-frequency protein-coding variation associated with age at natural menopause (ANM). We identified 44 regions with common variants, including two harbouring additional rare missense alleles of large effect. We found enrichment of signals in/near genes involved in delayed puberty, highlighting the first molecular links between the onset and end of reproductive lifespan. Pathway analyses revealed a major association with DNA damage-response (DDR) genes, including the first common coding variant in BRCA1 associated with any complex trait. Mendelian randomisation analyses supported a causal effect of later ANM on breast cancer risk (~6% risk increase per-year, P=3×10−14), likely mediated by prolonged sex hormone exposure, rather than DDR mechanisms. PMID:26414677

  7. Dropout in VET – institutional selection and social exclusion

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    Dropout – institutional selection and social exclusion For the last ten years dropout of vocational education has increased strongly in Denmark. The questions addressed in this paper are why and how dropout in VET takes place. The objective is to provide more detailed and qualified knowledge...... of the complex processes of dropping out. The present study is part of a large national research project on retention in VET. The paper aims to understand dropout as a result of the interplay of students’ agentic actions and social interactions and the opportunities for participation afforded by the colleges...

  8. Effect of magnetic susceptibility contrast medium on myocardial signal intensity with fast gradient-recalled echo and spin-echo MR imaging: initial experience in humans.

    Science.gov (United States)

    Sakuma, H; O'Sullivan, M; Lucas, J; Wendland, M F; Saeed, M; Dulce, M C; Watson, A; Bleyl, K L; LaFrance, N D; Higgins, C B

    1994-01-01

    To show the effect of dysprosium diethylenetriaminepentaacetic acid bis-methylamine injection on the images of normal human myocardium. T2-sensitive fast gradient-recalled echo (GRE) (repetition time [TR], 10.8 msec; echo time [TE], 4.2 msec) and spin-echo (SE) (TR, three RR intervals; TE, 60 msec) magnetic resonance (MR) imaging with driven equilibrium-preparation pulse was used to produce T2 contrast material enhancement. The contrast agent was injected into 12 healthy subjects at doses of 0.05, 0.1, 0.2, 0.4, and 0.6 mmol/kg. Driven equilibrium-prepared GRE images showed a transient decrease of myocardial signal intensity at doses of 0.2-0.6 mmol/kg. Postcontrast T2-weighted SE images showed a myocardial signal attenuation (30%-45% decrease) at a dose of 0.4 mmol/kg or higher. Dynamic MR imaging with a magnetic susceptibility contrast medium can be used to monitor the first pass of contrast media through human myocardium with a conventional MR imager and a fast GRE sequence.

  9. Dropout from Outpatient Mental Health Care in the United States

    Science.gov (United States)

    Olfson, Mark; Mojtabai, Ramin; Sampson, Nancy A.; Hwang, Irving; Kessler, Ronald C.

    2009-01-01

    Objectives Although mental health treatment dropout is common, patterns and predictors of dropout are poorly understood. This study explores patterns and predictors of mental health treatment dropout in a nationally representative sample. Methods Data come from the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey. Respondents in mental health treatment in the 12 months (n=1,664) before interview were asked about dropout defined as quitting treatment before the provider wanted. Cross-tabulation and discrete-time survival analyses were used to identify predictors. Results Approximately one-fifth (22.4%) of patients quit treatment prematurely. The highest dropout rate was from the general medical sector (31.6%) and the lowest was from psychiatrists (15.1%). Dropout rates were intermediate in the human service sector (19.7%) and among patients seen by non-psychiatrist mental health professionals (18.9%). Over 70% of all dropout occurred after the first or second visits. Mental health insurance was associated with low odds of dropout (0.6, 0.4–0.9). Psychiatric comorbidity was associated with a trend towards dropout. Several patient characteristics differentially predicted dropout across treatment sectors and in early and later phases of treatment. Conclusions Roughly one-fifth of adults in mental health treatment each year drop out before completing the recommended course of treatment. Dropout is most common in the general medical sector and varies by patient characteristics across treatment sectors. Interventions focused on high-risk patients and sectors will likely be required to reduce the high proportion of patients who prematurely terminate treatment. PMID:19564219

  10. Drop-out from a psychodynamic group psychotherapy outpatient unit.

    Science.gov (United States)

    Jensen, Hans Henrik; Mortensen, Erik Lykke; Lotz, Martin

    2014-11-01

    BACKGROUND. Drop-out from psychotherapy is common and represents a considerable problem in clinical practice and research. Aim. To explore pre-treatment predictors of early and late drop-out from psychodynamic group therapy in a public outpatient unit for non-psychotic disorders in Denmark. Methods. Naturalistic design including 329 patients, the majority with mood, neurotic and personality disorders referred to 39-session group therapy. Predictors were socio-demographic and clinical variables, self-reported symptoms (Symptom Check List-90-Revised) and personality style (Millon Clinical Multiaxial Inventory-II). Drop-out was classified into early and late premature termination excluding patients who dropped out for external reasons. Results. Drop-out comprised 20.6% (68 patients) of the sample. Logistic regression revealed social functioning, vocational training, alcohol problems and antisocial behavior to be related to drop-out. However, early drop-outs had prominent agoraphobic symptoms, lower interpersonal sensitivity and compulsive personality features, and late drop-outs cognitive and somatic anxiety symptoms and antisocial personality features. Clinical and psychological variables accounted for the major part of variance in predictions of drop-out, which ranged from 15.6% to 19.5% (Nagelkerke Pseudo R-Square). Conclusion. Social functioning was consistently associated with drop-out, but personality characteristics and anxiety symptoms differentiated between early and late drop-out. Failure to discriminate between stages of premature termination may explain some of the inconsistencies in the drop-out literature. Clinical implications. Before selection of patients to time-limited psychodynamic groups, self-reported symptoms should be thoroughly considered. Patients with agoraphobic symptoms should be offered alternative treatment. Awareness of and motivation to work with interpersonal issues may be essential for compliance with group therapy.

  11. Use of Holland's Vocational Theory with Potential High School Dropouts

    Science.gov (United States)

    Cunningham, Claude H.; And Others

    1977-01-01

    The construct validity for potential high school dropouts (N=252) of Holland's theory of vocational choice as measured by the Vocational Preference Inventory (VPI) was studied. Results indicate Holland's theory is appropriate for potential high school dropouts and by implication, for other high school students. (Author)

  12. Dropout from exercise programs for seniors: A prospective cohort study

    NARCIS (Netherlands)

    Stiggelbout, M.; Hopman-Rock, M.; Tak, E.; Lechner, L.; Mechelen, W. van

    2005-01-01

    This study examines dropout incidence, moment of dropout, and switching behavior in organized exercise programs for seniors in the Netherlands, as determined in a prospective cohort study (with baseline measurements at the start of the exercise program and follow-up after 6 months; N = 1,725,

  13. Higher Standards, More Dropouts? Evidence Within and across Time.

    Science.gov (United States)

    Lillard, Dean R.; DeCicca, Philip P.

    2001-01-01

    Investigates whether state course graduation requirements affect high-school dropout decisions, using aggregate data on dropout rates, individual data from two time periods, and aggregate data on high-school completion rates over 15 years. Results strongly suggest that state-mandated minimum course requirements cause students to drop out.…

  14. Aggressive Students and High School Dropout: An Event History Analysis

    Science.gov (United States)

    Orozco, Steven R.

    2016-01-01

    Aggressive students often struggle in multiple domains of their school functioning and are at increased risk for high school dropout. Research has identified a variety of warning flags which are strong predictors of high school dropout. While it is known that aggressive students exhibit many of these warning flags, there is little research which…

  15. Tennessee's High School Dropouts: Examining the Fiscal Consequences

    Science.gov (United States)

    D'Andrea, Christian

    2010-01-01

    High school dropouts adversely impact the state of Tennessee each year--financially and socially. Dropouts' lower incomes, high unemployment rates, increased need for medical care, and higher propensity for incarceration create a virtual vortex that consumes Tennesseans' tax dollars at a vicious rate. Hundreds of millions of dollars are spent on…

  16. Leadership and dropout prevention : strategies for school principals

    OpenAIRE

    2012-01-01

    D.Ed. The objective of this study is to explore and describe the viewpoints of rural black secondary school principals concerning their leadership responsibilities with regard to the prevention of dropout; to develop strategies for secondary school principals with regard to their leadership role in preventing school dropout and to describe guidelines for the implementation of the strategies

  17. Occupational Constraints and Opportunities Faced by School Dropouts

    Science.gov (United States)

    Kim, Kyung-Nyun

    2015-01-01

    This study investigated the relation between building human capital of former dropouts and their occupational standing and the interaction effects with individual characteristics. By applying the growth curve model, this study highlighted the factors that lead high school dropouts to enhance their occupational standing. An increment in the work…

  18. School Dropout Indicators, Trends, and Interventions for School Counselors

    Science.gov (United States)

    Dockery, Donna J.

    2012-01-01

    School counselors are expected to develop programs that promote academic success for all students, including those at risk for dropping out of school. Knowledge of key indicators of potential dropouts and current trends in dropout prevention research may assist school counselors in better understanding this complex issue. Implementing recommended…

  19. Parenting practices and school dropout: a longitudinal study.

    Science.gov (United States)

    Blondal, Kristjana S; Adalbjarnardottir, Sigrun

    2009-01-01

    Adolescents' perceptions of parenting style and parental involvement in their education were examined longitudinally and related to school dropout among Icelandic youth (N = 427). Results indicated that adolescents who, at age 14, characterized their parents as authoritative (showing acceptance and supervision) were more likely to have completed upper secondary school by age 22 than adolescents from non-authoritative families, controlling for adolescents' gender, socioeconomic status (SES), temperament, and parental involvement. Parenting style seems to more strongly predict school dropout than parental involvement. Further, parenting style may moderate the relationship between parental involvement and dropout, but not in all groups; only in authoritative families does parental involvement decrease the likelihood of school dropout. Furthermore, even after controlling for previous academic achievement, adolescents from authoritative families were less likely to drop out than adolescents from authoritarian and neglectful families. These findings emphasize the importance of encouraging quality parent-child relationships in order to reduce the likelihood of school dropout.

  20. Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility.

    Science.gov (United States)

    Lascorz, Jesús; Försti, Asta; Chen, Bowang; Buch, Stephan; Steinke, Verena; Rahner, Nils; Holinski-Feder, Elke; Morak, Monika; Schackert, Hans K; Görgens, Heike; Schulmann, Karsten; Goecke, Timm; Kloor, Matthias; Engel, Cristoph; Büttner, Reinhard; Kunkel, Nelli; Weires, Marianne; Hoffmeister, Michael; Pardini, Barbara; Naccarati, Alessio; Vodickova, Ludmila; Novotny, Jan; Schreiber, Stefan; Krawczak, Michael; Bröring, Clemens D; Völzke, Henry; Schafmayer, Clemens; Vodicka, Pavel; Chang-Claude, Jenny; Brenner, Hermann; Burwinkel, Barbara; Propping, Peter; Hampe, Jochen; Hemminki, Kari

    2010-09-01

    Genetic susceptibility accounts for approximately 35% of all colorectal cancer (CRC). Ten common low-risk variants contributing to CRC risk have been identified through genome-wide association studies (GWASs). In our GWAS, 610 664 genotyped single-nucleotide polymorphisms (SNPs) passed the quality control filtering in 371 German familial CRC patients and 1263 controls, and replication studies were conducted in four additional case-control sets (4915 cases and 5607 controls). Known risk loci at 8q24.21 and 11q23 were confirmed, and a previously unreported association, rs12701937, located between the genes GLI3 (GLI family zinc finger 3) and INHBA (inhibin, beta A) [P = 1.1 x 10(-3), odds ratio (OR) 1.14, 95% confidence interval (CI) 1.05-1.23, dominant model in the combined cohort], was identified. The association was stronger in familial cases compared with unselected cases (P = 2.0 x 10(-4), OR 1.36, 95% CI 1.16-1.60, dominant model). Two other unreported SNPs, rs6038071, 40 kb upstream of CSNK2A1 (casein kinase 2, alpha 1 polypeptide) and an intronic marker in MYO3A (myosin IIIA), rs11014993, associated with CRC only in the familial CRC cases (P = 2.5 x 10(-3), recessive model, and P = 2.7 x 10(-4), dominant model). Three software tools successfully pointed to the overrepresentation of genes related to the mitogen-activated protein kinase (MAPK) signalling pathways among the 1340 most strongly associated markers from the GWAS (allelic P value < 10(-3)). The risk of CRC increased significantly with an increasing number of risk alleles in seven genes involved in MAPK signalling events (P(trend) = 2.2 x 10(-16), OR(per allele) = 1.34, 95% CI 1.11-1.61).

  1. Dropouts and Social Determinants of Health; Policy for the Prevention of School Dropout, Qualitative Study of the Causes and Interventions

    Directory of Open Access Journals (Sweden)

    Maryam Rahbari

    2014-01-01

    Conclusions: The present study, with the presentation of statistical documents specifically of the current problem of school dropouts in all levels of the Iranian society has been determined and aside from identifying the causes and factors affecting school dropouts, provision of strategies in three levels of prevention to combat this problem has been addressed.

  2. Accelerated mapping of magnetic susceptibility using 3D planes-on-a-paddlewheel (POP) EPI at ultra-high field strength.

    Science.gov (United States)

    Stäb, Daniel; Bollmann, Steffen; Langkammer, Christian; Bredies, Kristian; Barth, Markus

    2017-04-01

    With the advent of ultra-high field MRI scanners in clinical research, susceptibility based MRI has recently gained increasing interest because of its potential to assess subtle tissue changes underlying neurological pathologies/disorders. Conventional, but rather slow, three-dimensional (3D) spoiled gradient-echo (GRE) sequences are typically employed to assess the susceptibility of tissue. 3D echo-planar imaging (EPI) represents a fast alternative but generally comes with echo-time restrictions, geometrical distortions and signal dropouts that can become severe at ultra-high fields. In this work we assess quantitative susceptibility mapping (QSM) at 7 T using non-Cartesian 3D EPI with a planes-on-a-paddlewheel (POP) trajectory, which is created by rotating a standard EPI readout train around its own phase encoding axis. We show that the threefold accelerated non-Cartesian 3D POP EPI sequence enables very fast, whole brain susceptibility mapping at an isotropic resolution of 1 mm and that the high image quality has sufficient signal-to-noise ratio in the phase data for reliable QSM processing. The susceptibility maps obtained were comparable with regard to QSM values and geometric distortions to those calculated from a conventional 4 min 3D GRE scan using the same QSM processing pipeline. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  3. Causes of Student Absenteeism and School Dropouts

    Directory of Open Access Journals (Sweden)

    Şeyma Şahin

    2016-01-01

    Full Text Available The aim of the study is to investigate the causes of student absenteeism and school dropouts at primary, secondary and high school level in Düzce Province and to develop suggestions for solving these problems. A “case study” design, which is one of the qualitative research approaches, was used in this study. The study group consisted of 64 school principals working at primary, secondary and high schools in the province center and districts of Düzce. A semi-structured interview form consisting of nine questions was used as the data collection tool. The collected data was analyzed by content analysis method. 15 main themes were formed under five categories. Certain suggestions were developed based on the findings obtained as the result of the study.

  4. Patterns and Factors of High School Dropout Risks of Racial and Linguistic Groups

    Science.gov (United States)

    Kim, Sunha; Chang, Mido; Singh, Kusum; Allen, Katherine R.

    2015-01-01

    This study examined the dropout trajectories of racial and linguistic minority students and explored the effects of students' contextual factors on their high school dropout risks. Our motivation was to identify the dropout patterns of Black, Hispanic, and Hispanic English language learner (ELL) students, who have comparatively high dropout rates,…

  5. Model-Free Adaptive Control Algorithm with Data Dropout Compensation

    Directory of Open Access Journals (Sweden)

    Xuhui Bu

    2012-01-01

    Full Text Available The convergence of model-free adaptive control (MFAC algorithm can be guaranteed when the system is subject to measurement data dropout. The system output convergent speed gets slower as dropout rate increases. This paper proposes a MFAC algorithm with data compensation. The missing data is first estimated using the dynamical linearization method, and then the estimated value is introduced to update control input. The convergence analysis of the proposed MFAC algorithm is given, and the effectiveness is also validated by simulations. It is shown that the proposed algorithm can compensate the effect of the data dropout, and the better output performance can be obtained.

  6. Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

    NARCIS (Netherlands)

    Zhang, Mingfeng; Wang, Zhaoming; Obazee, Ofure; Jia, Jinping; Childs, Erica J; Hoskins, Jason; Figlioli, Gisella; Mocci, Evelina; Collins, Irene; Chung, Charles C; Hautman, Christopher; Arslan, Alan A; Beane-Freeman, Laura; Bracci, Paige M; Buring, Julie; Duell, Eric J; Gallinger, Steven; Giles, Graham G; Goodman, Gary E; Goodman, Phyllis J; Kamineni, Aruna; Kolonel, Laurence N; Kulke, Matthew H; Malats, Núria; Olson, Sara H; Sesso, Howard D; Visvanathan, Kala; White, Emily; Zheng, Wei; Abnet, Christian C; Albanes, Demetrius; Andreotti, Gabriella; Brais, Lauren; Bueno-de-Mesquita, H Bas; Basso, Daniela; Berndt, Sonja I; Boutron-Ruault, Marie-Christine; Bijlsma, Maarten F; Brenner, Hermann; Burdette, Laurie; Campa, Daniele; Caporaso, Neil E; Capurso, Gabriele; Cavestro, Giulia Martina; Cotterchio, Michelle; Costello, Eithne; Elena, Joanne; Boggi, Ugo; Gaziano, J Michael; Gazouli, Maria; Giovannucci, Edward L; Goggins, Michael; Gross, Myron; Haiman, Christopher A; Hassan, Manal; Helzlsouer, Kathy J; Hu, Nan; Hunter, David J; Iskierka-Jazdzewska, Elzbieta; Jenab, Mazda; Kaaks, Rudolf; Key, Timothy J; Khaw, Kay-Tee; Klein, Eric A; Kogevinas, Manolis; Krogh, Vittorio; Kupcinskas, Juozas; Kurtz, Robert C; Landi, Maria T; Landi, Stefano; Le Marchand, Loic; Mambrini, Andrea; Mannisto, Satu; Milne, Roger L; Neale, Rachel E; Oberg, Ann L; Panico, Salvatore; Patel, Alpa V; Peeters, Petra H M; Peters, Ulrike; Pezzilli, Raffaele; Porta, Miquel; Purdue, Mark; Quiros, J Ramón; Riboli, Elio; Rothman, Nathaniel; Scarpa, Aldo; Scelo, Ghislaine; Shu, Xiao-Ou; Silverman, Debra T; Soucek, Pavel; Strobel, Oliver; Sund, Malin; Małecka-Panas, Ewa; Taylor, Philip R; Tavano, Francesca; Travis, Ruth C; Thornquist, Mark; Tjønneland, Anne; Tobias, Geoffrey S; Trichopoulos, Dimitrios; Vashist, Yogesh; Vodicka, Pavel; Wactawski-Wende, Jean; Wentzensen, Nicolas; Yu, Herbert; Yu, Kai; Zeleniuch-Jacquotte, Anne; Kooperberg, Charles; Risch, Harvey A; Jacobs, Eric J; Li, Donghui; Fuchs, Charles; Hoover, Robert; Hartge, Patricia; Chanock, Stephen J; Petersen, Gloria M; Stolzenberg-Solomon, Rachael S; Wolpin, Brian M; Kraft, Peter; Klein, Alison P; Canzian, Federico; Amundadottir, Laufey T

    2016-01-01

    Genome-wide association studies (GWAS) have identified common pancreatic cancer susceptibility variants at 13 chromosomal loci in individuals of European descent. To identify new susceptibility variants, we performed imputation based on 1000 Genomes (1000G) Project data and association analysis

  7. Unconditionally Stable Low Dropout Regulators for Extreme Environments Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We have developed a low dropout (LDO) regulator using a patented MESFET transistor technology that can be manufactured in commercial CMOS foundries with no changes...

  8. Socioeconomic differences in school dropout among young adults

    DEFF Research Database (Denmark)

    Winding, Trine Nøhr; Andersen, Johan Hviid

    2015-01-01

    Background School dropout in adolescence is an important social determinant of health inequality in a lifetime perspective. It is commonly accepted that parental background factors are associated with later dropout, but to what extent social relations mediate this association is not yet fully...... understood. Aim: To investigate the effect of social relations on the association between parental socioeconomic position and school dropout in the Danish youth cohort Vestliv. Methods This prospective study used data from questionnaires in 2004 and 2007 and register data in 2004 and 2010. The study...... between parental socioeconomic position and dropout at age 21, taking into account effects of social relations at age 15 and 18. Results A large proportion of young people were having problems with social relations at age 15 and 18. In general, social relations were strongly related to not completing...

  9. Student engagement and its relationship with early high school dropout.

    Science.gov (United States)

    Archambault, Isabelle; Janosz, Michel; Fallu, Jean-Sébastien; Pagani, Linda S

    2009-06-01

    Although the concept of school engagement figures prominently in most school dropout theories, there has been little empirical research conducted on its nature and course and, more importantly, the association with dropout. Information on the natural development of school engagement would greatly benefit those interested in preventing student alienation during adolescence. Using a longitudinal sample of 11,827 French-Canadian high school students, we tested behavioral, affective, cognitive indices of engagement both separately and as a global construct. We then assessed their contribution as prospective predictors of school dropout using factor analysis and structural equation modeling. Global engagement reliably predicted school dropout. Among its three specific dimensions, only behavioral engagement made a significant contribution in the prediction equation. Our findings confirm the robustness of the overall multidimensional construct of school engagement, which reflects both cognitive and psychosocial characteristics, and underscore the importance attributed to basic participation and compliance issues in reliably estimating risk of not completing basic schooling during adolescence.

  10. Influence of mental disorders on school dropout in Mexico.

    Science.gov (United States)

    Borges, Guilherme; Medina Mora-Icaza, María Elena; Benjet, Corina; Lee, Sing; Lane, Michael; Breslau, Joshua

    2011-11-01

    To study the impact of mental disorders on failure in educational attainment in Mexico. Diagnoses and age of onset for each of 16 DSM-IV disorders were assessed through retrospective self-reports with the Composite International Diagnostic Instrument (CIDI) during fieldwork in 2001-2002. Survival analysis was used to examine associations between early onset DSM-IV/CIDI disorders and subsequent school dropout or failure to reach educational milestones. More than one of two Mexicans did not complete secondary education. More than one-third of those who finished secondary education did not enter college, and one of four students who entered college did not graduate. Impulse control disorders and substance use disorders were associated with higher risk for school dropout, secondary school dropout and to a lesser degree failure to enter college. Anxiety disorders were associated with lower risk for school dropout, especially secondary school dropout and, to a lesser degree, primary school dropout. The heterogeneity of results found in Mexico may be due to the effect of mental disorders being diminished or masked by the much greater effect of economic hardship and low cultural expectations for educational achievement. Future research should inquire deeper into possible reasons for the better performance of students with anxiety disorders in developing countries.

  11. Lysophosphatidylcholine enhances susceptibility in signaling pathway against pathogen infection through biphasic production of reactive oxygen species and ethylene in tobacco plants.

    Science.gov (United States)

    Wi, Soo Jin; Seo, So yeon; Cho, Kyoungwon; Nam, Myung Hee; Park, Ky Young

    2014-08-01

    It was previously reported that the amounts of lysophosphatidylcholines (lysoPCs), which are naturally occurring bioactive lipid molecules, significantly increase following pathogen inoculation, as determined using ultraperformance liquid chromatography-quadrupole-time of flight/mass spectrometry analyses. Here, real-time quantitative RT-PCR was performed for the phospholipase A2 (PLA2) genes, Nt1PLA2 and Nt2PLA2, which are responsible for LysoPCs generation. The transcription level of Nt2PLA2 in pathogen-infected tobacco plants transiently peaked at 1h and 36 h, whereas induction of Nt1PLA2 transcription peaked at 36 h. A prominent biphasic ROS accumulation in lysoPC (C18:1(9Z))-treated tobacco leaves was also observed. Transcription of NtRbohD, a gene member of NADPH oxidase, showed biphasic kinetics upon lysoPC 18:1 treatment, as evidenced by an early transient peak in phase I at 1h and a massive peak in phase II at 12h. Each increase in NtACS2 and NtACS4 transcription, gene members of the ACC synthase family, was followed by biphasic peaks of ethylene production after lysoPC 18:1 treatment. This suggested that lysoPC (C18:1)-induced ethylene production was regulated at the transcriptional level of time-dependent gene members. LysoPC 18:1 treatment also rapidly induced cell damage. LysoPC 18:1-induced cell death was almost completely abrogated in ROS generation-impaired transgenic plants (rbohD-as and rbohF-as), ethylene production-impaired transgenic plants (CAS-AS and CAO-AS), and ethylene signaling-impaired transgenic plants (Ein3-AS), respectively. Taken together, pathogen-induced lysoPCs enhance pathogen susceptibility accompanied by ROS and ethylene biosynthesis, resulting in chlorophyll degradation and cell death. Expression of PR genes (PR1-a, PR-3, and PR-4b) and LOX3 was strongly induced in lysoPC 18:1-treated leaves, indicating the involvement of lysoPC 18:1 in the defense response. However, lysoPC 18:1 treatment eventually resulted in cell death, as

  12. Review of GEM Radiation Belt Dropout and Buildup Challenges

    Science.gov (United States)

    Tu, Weichao; Li, Wen; Morley, Steve; Albert, Jay

    2017-04-01

    In Summer 2015 the US NSF GEM (Geospace Environment Modeling) focus group named "Quantitative Assessment of Radiation Belt Modeling" started the "RB dropout" and "RB buildup" challenges, focused on quantitative modeling of the radiation belt buildups and dropouts. This is a community effort which includes selecting challenge events, gathering model inputs that are required to model the radiation belt dynamics during these events (e.g., various magnetospheric waves, plasmapause and density models, electron phase space density data), simulating the challenge events using different types of radiation belt models, and validating the model results by comparison to in situ observations of radiation belt electrons (from Van Allen Probes, THEMIS, GOES, LANL/GEO, etc). The goal is to quantitatively assess the relative importance of various acceleration, transport, and loss processes in the observed radiation belt dropouts and buildups. Since 2015, the community has selected four "challenge" events under four different categories: "storm-time enhancements", "non-storm enhancements", "storm-time dropouts", and "non-storm dropouts". Model inputs and data for each selected event have been coordinated and shared within the community to establish a common basis for simulations and testing. Modelers within and outside US with different types of radiation belt models (diffusion-type, diffusion-convection-type, test particle codes, etc.) have participated in our challenge and shared their simulation results and comparison with spacecraft measurements. Significant progress has been made in quantitative modeling of the radiation belt buildups and dropouts as well as accessing the modeling with new measures of model performance. In this presentation, I will review the activities from our "RB dropout" and "RB buildup" challenges and the progresses achieved in understanding radiation belt physics and improving model validation and verification.

  13. Dropouts and social determinants of health; policy for the prevention of school dropout, qualitative study of the causes and interventions.

    Science.gov (United States)

    Rahbari, Maryam; Hajnaghizadeh, Fatemeh; Damari, Behzad; Adhami, Behzad

    2014-11-01

    Indicators of the level of education are the most important parameters influencing each country's development. Social indicators considered to be a determinant of one's health consists of two constituents namely; (1) Rate of students enrolled in elementary, guidance, secondary and higher education and (2) the rate of adult literacy. This study is aimed to evaluate the situation of school dropouts in Iran, their causes, and appropriate interventions. Data were collected through literature review (including published researches and analysis of documents), focus group discussions with the presence of experts from (Department of Community Health, Academy of Medical Sciences) and interviews with stakeholders then these data were classified and presented in three sections namely; current situation, causes and solutions. Results showed that Iran's current situation in terms of school dropouts is unsatisfactory in comparison to developed countries and in some countries in the region. Influencing factors for school dropouts were classified into (1) Individual factors such as intellectual disability and behavioral disorders (2) group factors such as peer groups, family problems and children's reduced interests in school and (3) major factors such as educational system and the changes of value, economic, cultural, and political issues. The present study, with the presentation of statistical documents specifically of the current problem of school dropouts in all levels of the Iranian society has been determined and aside from identifying the causes and factors affecting school dropouts, provision of strategies in three levels of prevention to combat this problem has been addressed.

  14. Suicidality, school dropout, and reading problems among adolescents.

    Science.gov (United States)

    Daniel, Stephanie S; Walsh, Adam K; Goldston, David B; Arnold, Elizabeth M; Reboussin, Beth A; Wood, Frank B

    2006-01-01

    The purpose of this study was to examine the risk of suicidal ideation and suicide attempts and school dropout among youth with poor reading in comparison to youth with typical reading (n = 188) recruited from public schools at the age of 15. In a prospective naturalistic study, youth and parents participated in repeated research assessments to obtain information about suicide ideation and attempts, psychiatric and sociodemographic variables, and school dropout. Youth with poor reading ability were more likely to experience suicidal ideation or attempts and more likely to drop out of school than youth with typical reading, even after controlling for sociodemographic and psychiatric variables. Suicidality and school dropout were strongly associated with each other. Prevention efforts should focus on better understanding the relationship between these outcomes, as well as on the developmental paths leading up to these behaviors among youth with reading difficulties.

  15. Exploring the Impacts of Ordinary Laboratory Alterations During Forensic DNA Processing on Peak Height Variation, Thresholds, and Probability of Dropout.

    Science.gov (United States)

    Rowan, Kayleigh E; Wellner, Genevieve A; Grgicak, Catherine M

    2016-01-01

    Impacts of validation design on DNA signal were explored, and the level of variation introduced by injection, capillary changes, amplification, and kit lot was surveyed by examining a set of replicate samples ranging in mass from 0.25 to 0.008 ng. The variations in peak height, heterozygous balance, dropout probabilities, and baseline noise were compared using common statistical techniques. Data indicate that amplification is the source of the majority of the variation observed in the peak heights, followed by capillary lots. The use of different amplification kit lots did not introduce variability into the peak heights, heterozygous balance, dropout, or baseline. Thus, if data from case samples run over a significant time period are not available during validation, the validation must be designed to, at a minimum, include the amplification of multiple samples of varying quantity, with known genotype, amplified and run over an extended period of time using multiple pipettes and capillaries. © 2015 American Academy of Forensic Sciences.

  16. Why Wait? Early Determinants of School Dropout in Preventive Pediatric Primary Care: e0142315

    National Research Council Canada - National Science Library

    Marie-José Theunissen; Hans Bosma; Petra Verdonk; Frans Feron

    2015-01-01

    ... process towards school dropout as a multidimensional, life-course phenomenon. The aim is to find signs of heightened risks of school dropout as early as possible which will eventually help public health workers in reducing these risks...

  17. A Semiparametric Marginalized Model for Longitudinal Data with Informative Dropout

    Directory of Open Access Journals (Sweden)

    Mengling Liu

    2012-01-01

    Full Text Available We propose a marginalized joint-modeling approach for marginal inference on the association between longitudinal responses and covariates when longitudinal measurements are subject to informative dropouts. The proposed model is motivated by the idea of linking longitudinal responses and dropout times by latent variables while focusing on marginal inferences. We develop a simple inference procedure based on a series of estimating equations, and the resulting estimators are consistent and asymptotically normal with a sandwich-type covariance matrix ready to be estimated by the usual plug-in rule. The performance of our approach is evaluated through simulations and illustrated with a renal disease data application.

  18. Back-dropout Transfer Learning for Action Recognition

    DEFF Research Database (Denmark)

    Ren, Huamin; Kanhabua, Nattiya; Møgelmose, Andreas

    2018-01-01

    transfer learning being a promising approach, it is still an open question how to adapt the model learned from the source dataset to the target dataset. One big challenge is to prevent the impact of category bias on classification performance. Dataset bias exists when two images from the same category......, but from different datasets, are not classified as the same. To address this problem, we propose a transfer learning algorithm which takes advantage of misclassified images and applies back-dropout strategy to punish errors. We call this Negative Back-dropout Transfer Learning (NB-TL). Experimental results...

  19. The Annual Dropout Report 1987-88. OREA Report. Accountability Section Report.

    Science.gov (United States)

    Opperman, Prudence; Gampert, Richard D.

    Examination of dropout trends in New York City for 1987-88 reveals the following: (1) the annual dropout rate was 7.5 percent for the high schools, and 8.4 percent system-wide; (2) the estimated 4-year dropout rate was 26.8 percent for the high schools, and 29.7 percent system-wide; (3) the 1987-88 4-year high school dropout rate was 5.7…

  20. Therapeutic relationship and dropout in youth mental health care with ethnic minority children and adolescents

    NARCIS (Netherlands)

    de Haan, A.M.; Boon, A.E.; de Jong, J.T.V.M.; Geluk, C.A.M.L.; Vermeiren, R.R.J.M.

    2014-01-01

    Background Dropout in youth psychotherapy is high, especially for ethnic minority patients. An important determinant of dropout is the quality of the therapeutic relationship. This study evaluated the association between the therapeutic relationship and dropout in therapy with ethnic minority youth.

  1. The impact of community schools on student dropout in pre-vocational education

    NARCIS (Netherlands)

    Heers, M.; van Klaveren, C.; Groot, W.; Maassen van den Brink, H.

    2014-01-01

    Dropout prevention is highly ranked on the political agenda in many countries. It remains unclear, however, how dropout can be effectively reduced, as many different factors determine student dropout. Community schools recognize this and aim to modernize education such that it better accommodates

  2. The impact of community schools on student dropout in pre-vocational education

    NARCIS (Netherlands)

    Heers, M.; van Klaveren, C.; Groot, W.; Maassen van den Brink, H.

    2012-01-01

    Dropout prevention is highly ranked on the political agenda in many countries. It remains unclear, however, how dropout can be effectively reduced, as many different factors are determining student dropout. Community schools recognize this and modernize education such that it better accommodates

  3. Is Drop-Out from University Dependent on National Culture and Policy? The Case of Denmark

    Science.gov (United States)

    Troelsen, Rie; Laursen, Per F.

    2014-01-01

    National cultures are known to influence educational institutions and practices in many ways. It therefore seems reasonable to assume that drop-out from university is also influenced by differences in national cultures. In this article, we compare drop-out from Danish universities with drop-out from European universities. Based on Danish national…

  4. Texas School Dropout Survey: A Report to the 69th Legislature, State of Texas.

    Science.gov (United States)

    Texas State Dept. of Community Affairs, Austin. Training and Employment Development Div.

    As a response to legislative demands, the Texas School Dropout Survey described in this document attempted to identify the magnitude of the dropout problem, regional characteristics or causes of the problem, costs associated with dropping out, and programs currently available for serving the dropout population. Twenty-four major findings of the…

  5. Tracking Drop-out Students in Palestinian Refugee Camps in Lebanon

    Science.gov (United States)

    Al-Hroub, Anies

    2015-01-01

    This research paper examines the perceptions of students on the school drop-out problem in Palestinian refugee camps in Lebanon regarding (a) the social and economic causes associated with the phenomenon of school drop-out; (b) the educational policies and practices used in UNRWA schools and their relationship to student drop-out; and (c) the role…

  6. 20 CFR 664.310 - When is dropout status determined, particularly for youth attending alternative schools?

    Science.gov (United States)

    2010-04-01

    ... INVESTMENT ACT Out-of-School Youth § 664.310 When is dropout status determined, particularly for youth attending alternative schools? A school dropout is defined as an individual who is no longer attending any... dropout status is determined at the time of registration. A youth attending an alternative school at the...

  7. Exploring the Impact of Career Mentoring on High School Dropout: A Qualitative Phenomenological Investigation

    Science.gov (United States)

    Raffington Ameir, Caroline

    2012-01-01

    According to Department of Education reports on public high school dropout rates for 2009, a national average of 44.3% of dropouts left their secondary school education in the 11th and 12th grades. The majority of school dropouts attributed the reason for dropping out of school to boredom. High social and economic costs associated with dropping…

  8. Hidden School Dropout among Immigrant Students: A Cross-Sectional Study

    Science.gov (United States)

    Makarova, Elena; Herzog, Walter

    2013-01-01

    Actual school dropout among immigrant youth has been addressed in a number of studies, but research on hidden school dropout among immigrant students is rare. Thus, the objective of this paper is to analyze hidden school dropout among primary school students with an immigrant background. The analyses were performed using survey data of 1186…

  9. The reasons of dropout of sport in Hong Kong school athletes.

    Science.gov (United States)

    Hassan, Abdul-Rahman; Lam, Michael Huen Sum; Ku, Susanna; Li, William Ho Cheung; Lee, Ka Yiu; Ho, Eva; Flint, Stuart W; Wong, Anthony Siu Wo

    2017-05-16

    Dropout of sport is an issue in sport and public health domains. The aim of this study was to identify the potential dropout reasons of school athletes and to examine if their perception of dropout was affected by the previous dropout experience. There were 50 subjects who were divided into two groups based on their previous dropout experience (Dropout Group=22, No Dropout Group=28). They filled a questionnaire about potential dropout reasons of the current sport. Coach and teammates were two predominated reasons of dropout; Influence of parent and training seemed to affect the termination of the sport to a lesser extent. Moreover, the perception of social value and lost focus were significantly different between two groups. Character of coach and teammates affect the engagement of training in school athletes. However, the parental influence had less influence than expected. Training intensity played little role as the dropout reason. Previous experience of dropout had an impact of potential dropout reasons on their current sport training.

  10. Personal and Social Contributors to Dropout Risk for Undergraduate Students

    Science.gov (United States)

    McGaha, Valerie; Fitzpatrick, Jacki

    2005-01-01

    The purpose of the present study was to examine how personal characteristics (e.g., loneliness, interpersonal competence) and social characteristics (e.g., marginality) contributed to dropout risk among undergraduate students. The respondents (n=127 undergraduates) completed a questionnaire packet to assess all of the variables. Regression…

  11. Predictors of lifestyle intervention outcome and dropout: the SLIM study

    NARCIS (Netherlands)

    Roumen, C.; Feskens, E.J.M.; Corpeleijn, E.; Mensink, M.R.; Saris, W.H.M.; Blaak, E.E.

    2011-01-01

    Original Article European Journal of Clinical Nutrition (2011) 65, 1141–1147; doi:10.1038/ejcn.2011.74; published online 18 May 2011 Predictors of lifestyle intervention outcome and dropout: the SLIM study C Roumen1, E J M Feskens2, E Corpeleijn1, M Mensink2, W H M Saris1 and E E Blaak1 1Department

  12. Predictors of lifestyle intervention outcome and dropout : the SLIM study

    NARCIS (Netherlands)

    Roumen, C; Feskens, E J M; Corpeleijn, E; Mensink, M; Saris, W H M; Blaak, E E

    2011-01-01

    BACKGROUND/OBJECTIVES: To evaluate the effect of a 4.1-year (range 3-6 years) lifestyle intervention according to general public health recommendations on glucose tolerance and dropout in a Dutch population with impaired glucose tolerance (IGT). SUBJECTS/METHODS: In the Study on Lifestyle

  13. Teacher professionalisation and dropout rates in adult education

    DEFF Research Database (Denmark)

    Wahlgren, Bjarne; Mariager-Anderson, Kristina

    2015-01-01

    in by the teachers, interviews with the teachers, and by the teachers’ written logbooks. The preliminary conclusion is that it is the general attitude in the teacher groups towards the importance of improving retention that is of significance for the documented effects on the drop-out rates....

  14. Access, pass, throughput and dropout rates: Review of a problem ...

    African Journals Online (AJOL)

    Access, pass, throughput and dropout rates: Review of a problem-based learning BPharm curriculum at a previously disadvantaged university in South Africa. ... Access, pass and throughput rates, and failure to complete the course, were determined for a cohort of students (n=458). Results. All applications from 1999 to ...

  15. Repeated retention or dropout? Disputing Hobson's choice in South ...

    African Journals Online (AJOL)

    South Africa, like many developing countries, is heavily burdened by high dropout and unemployment rates and an undersupply of skilled workers. Grade retention is a common practice when learners do not meet the specific requirements – especially in countries with limited socio-economic resources. In South Africa, 52% ...

  16. A comparison of outer electron radiation belt dropouts during solar ...

    Indian Academy of Sciences (India)

    Energetic electrons are trapped in the Earth's radiation belts which occupy a toroidal region between 3 and 7 RE above the Earth's surface. Rapid loss of electrons from the radiation belts is known as dropouts. The source and loss mechanisms regulating the radiation belts population are not yet understood entirely, ...

  17. The Challenge for Career Development: Preventing Special Education Dropouts.

    Science.gov (United States)

    Razeghi, Jane A.

    1996-01-01

    Discusses characteristics and behavior patterns of students with disabilities who are most likely to drop out. Explores the impact of educational reform's emphasis on academics and on preparing all student with disabilities for employment and independent living, and identifies strategies to overcome the special education dropout problem. (CR)

  18. Comparison of urban and rural dropout rates of distance students ...

    African Journals Online (AJOL)

    As a country, it also has a history of forced location and the withholding of resources, including quality education, from certain rural areas. This study investigates, the effect of urbanisation (of the area in which a student resides) on the dropout rate of distance students in an introductory taxation course. Using Kember's ...

  19. The Rural Dropout Problem: An Invisible Achievement Gap

    Science.gov (United States)

    Johnson, Jerry; Strange, Marty; Madden, Karen

    2010-01-01

    This report reviews high school dropout rates and related factors in rural high schools throughout 15 Southern and Southwestern states. These schools are in districts that are among the 800 rural districts with the highest student poverty rate nationally. Seventy-seven percent of the "Rural 800" districts and 87 percent of the students in them are…

  20. Allelic drop-out probabilities estimated by logistic regression

    DEFF Research Database (Denmark)

    Tvedebrink, Torben; Eriksen, Poul Svante; Asplund, Maria

    2012-01-01

    We discuss the model for estimating drop-out probabilities presented by Tvedebrink et al. [7] and the concerns, that have been raised. The criticism of the model has demonstrated that the model is not perfect. However, the model is very useful for advanced forensic genetic work, where allelic dro...

  1. DIMENSIONS OF BASIC SCHOOL DROPOUTS IN RURAL GHANA ...

    African Journals Online (AJOL)

    MR PRINCE

    Indian hemp”. Such children normally leave home and instead of going to school they secretly join their friends, who may be school dropouts themselves but are now what is commonly re- ferred to as “station boys”. These boys are nor-.

  2. Immunization Dropout Rates in Ihe, Awgu Local Government Area ...

    African Journals Online (AJOL)

    Background: Immunization against childhood diseases is one of the most important ways of preventing childhood morbidity and mortality. Aims: The objective of this study is to review the dropout rates of immunization of children in a health center using a single dose of diphtheria‑pertussis‑tetanus (DPT1) and three doses of ...

  3. Final Evaluation Report on the Texarkana Dropout Prevention Program.

    Science.gov (United States)

    Andrew, Dean C.; Roberts, Lawrence H.

    The Texarkana Dropout Prevention Program is an educational innovation in which (1) a private company was placed under contract to set up special, remedial instruction in the public schools, and (2) the company was to be paid according to the results produced under a performance contract. Dorsett Educational Systems operated six rapid learning…

  4. 70001: From Soaps to Hopes for School Dropouts.

    Science.gov (United States)

    Sizemore, Donna Lynn

    1985-01-01

    Describes the activities and achievements of Broome County Catholic Youth Organization 70001, a unique program for economically disadvantaged youth and high school dropouts, which offers preemployment training, educational upgrading, motivational activities, and job placement assistance. Explains the benefits for the young participants, community,…

  5. Factors Affecting Students' Enrolment and Dropout at The Open ...

    African Journals Online (AJOL)

    Identified dropout problems were related to social, personal, financial, academic, students support services and cultural factors. It is recommended that raising ... OUT should upgrade to College level, the Regional centres and decentralize them to District levels with the help from the Government. Females need to be ...

  6. Trend And Causes Of Female Students Dropout From Teacher ...

    African Journals Online (AJOL)

    This article examines the state of female students' enrollment and dismissal rate and major factors that cause them to dropout from the higher learning institutions. Data were collected from the drop out students, instructors, gender officers and guidance and counseling office of the University through questionnaires, interview ...

  7. A retrospective transversal study of enlargement and college dropout

    OpenAIRE

    Cabrera, Lidia; Bethencourt Benítez, José Tomás; Miriam GONZÁLEZ AFONSO; Pedro ÁLVAREZ PÉREZ

    2006-01-01

    At present leaving and prolonging studies constitutes a serious problem at the university level. This report pre-sents the results of a retrospective transversal study which purpose was to identify risk factors related with dropout. The methodology design used can be for help

  8. Causes of Dropouts among CAMFED Bursary Supported School ...

    African Journals Online (AJOL)

    The study investigated the causes of dropouts among students under the CAMFED (Campaign for Female Education) Bursary programme. The target population of the study was 53 secondary schools in all 5 clusters in Buhera district of Manicaland province in Zimbabwe. One cluster, Chirozva, out of five clusters was ...

  9. Dropout and Violence Needs Assessment: A Follow-up Study

    Science.gov (United States)

    Miltich, Aimee P.; Hunt, Mary Helen; Meyers, Joel

    2004-01-01

    The current study investigated a needs assessment survey designed to measure perceptions of causes of dropout and school violence and related interventions. The needs assessment was conceptualized as a first step to be taken by schools to facilitate program planning, school-based implementation and acceptability of programs designed to prevent…

  10. A Case Study into the Causes of School Dropout

    Science.gov (United States)

    Chirtes, Gabriela

    2010-01-01

    School dropout leads to failure in social integration, and as a result greatly diminishes a person's chances to achieve personal success in legally accepted fields of activity. The prevention and reduction of this phenomenon are extremely difficult to achieve due to the high complexity of its causes. Research that has been carried out into this…

  11. The Societal Benefits and Costs of School Dropout Recovery

    Directory of Open Access Journals (Sweden)

    James S. Catterall

    2011-01-01

    Full Text Available This article reports an analysis of the societal benefits and costs of recovering school dropouts. Successful recovery is defined by subsequent graduation from high school. The analysis is based on established estimates of the societal costs of dropping out including reduced government tax collections and higher social costs of welfare, healthcare, and crime. These potential costs are cast as benefits when a dropout is recovered. A large dropout recovery program provides the setting for the analysis. Rigorous attention is given to accurate estimation of the number of students who would not have graduated without the program in the year assessed and to the induced public costs of their continued education. Estimated benefits are weighed against the total annual public costs of the program, which operates in 65 school centers and commands an annual budget of about $70 million. The estimated benefit-cost ratio for this program is 3 to 1, a figure comparable to benefit-cost ratio estimates reported in studies of dropout prevention. The sensitivity of this conclusion to specific assumptions within the analysis is discussed.

  12. Grade Repetition and Primary School Dropout in Uganda

    Science.gov (United States)

    Kabay, Sarah

    2016-01-01

    Research on education in low-income countries rarely focuses on grade repetition. When addressed, repetition is typically presented along with early school dropout as the "wasting" of educational resources. Simplifying grade repetition in this way often fails to recognize significant methodological concerns and also overlooks the unique…

  13. Rural and Urban High School Dropout Rates: Are They Different?

    Science.gov (United States)

    Jordan, Jeffrey L.; Kostandini, Genti; Mykerezi, Elton

    2012-01-01

    This study estimates the high school dropout rate in rural and urban areas, the determinants of dropping out, and whether the differences in graduation rates have changed over time. We use geocoded data from two nationally representative panel household surveys (NLSY 97 and NLSY 79) and a novel methodology that corrects for biases in graduation…

  14. Reasons for School Dropout in Vocational High School

    Science.gov (United States)

    Polat, Selda

    2014-01-01

    This study aims to discuss the causative factors that lead to vocational high schools dropout by referring to the opinions of the students who did leave the school. A qualitative phenomenological research method has been designed and adopted. The study group consisted of 19 children and young adults (15-24 years old) who continue their education…

  15. Montana's High School Dropouts: Examining the Fiscal Consequences. State Research

    Science.gov (United States)

    Stuit, David A.; Springer, Jeffrey A.

    2010-01-01

    This report analyzes the economic and social costs of the high school dropout problem in Montana from the perspective of a state taxpayer. The majority of the authors' analysis considers the consequences of this problem in terms of labor market, tax revenue, and public service costs. In quantifying these costs, the authors seek to inform public…

  16. The School Counselor's Role in School Dropout Prevention

    Science.gov (United States)

    White, Susan Williams; Kelly, F. Donald

    2010-01-01

    The role of the school counselor has undergone numerous revisions over the past few decades. The current emphasis on accountability and academic performance of students has forced counselors to scrutinize their role in promoting students' academic success and school completion. In this article, the authors review the problem of school dropout from…

  17. Understanding the Mechanism behind Maternal Imprisonment and Adolescent School Dropout

    Science.gov (United States)

    Cho, Rosa M.

    2011-01-01

    This study empirically tested 3 mechanisms commonly suggested to disadvantage youths whose mothers are incarcerated in prison. An event history analysis of school dropout was conducted on a sample of 6,008 adolescents in a large city created by merging several Illinois state administrative data. Findings revealed that adolescents are indeed at…

  18. Authoritative School Climate and High School Dropout Rates

    Science.gov (United States)

    Jia, Yuane; Konold, Timothy R.; Cornell, Dewey

    2016-01-01

    This study tested the association between school-wide measures of an authoritative school climate and high school dropout rates in a statewide sample of 315 high schools. Regression models at the school level of analysis used teacher and student measures of disciplinary structure, student support, and academic expectations to predict overall high…

  19. Children's educational completion rates and dropouts in the context ...

    African Journals Online (AJOL)

    Using a young Lives project data3, a combination of quantitative and qualitative method was used to analyse the determinants of school completion/dropout of children from primary education. A Cox box proportional hazard model was used to analyse the survival of children in primary education. The findings have ...

  20. Differential Developmental Pathways of High School Dropouts and Graduates

    Science.gov (United States)

    Hickman, Gregory P.; Bartholomew, Mitchell; Mathwig, Jennifer; Heinrich, Randy S.

    2008-01-01

    The authors examined the developmental pathways between high school graduates and dropouts. The authors obtained official school data via a random sample of 119 students enrolled across 4 cohorts. The authors postulated 2 research questions: (a) Do differences exist in the developmental pathways of high school graduates in comparison with high…

  1. California's High School Dropouts: Examining the Fiscal Consequences

    Science.gov (United States)

    Stuit, David A.; Springer, Jeffrey A.

    2010-01-01

    This report analyzes the economic and social costs of the high school dropout problem in California from the perspective of a state taxpayer. The authors' analysis considers the consequences of this problem in terms of labor market, tax revenue, public health, and incarceration costs. The authors' quantification of these costs reveals the sizeable…

  2. Emotional variables, dropout and academic performance in Spanish nursing students.

    Science.gov (United States)

    Roso-Bas, Fátima; Pades Jiménez, Antonia; García-Buades, Esther

    2016-02-01

    The dropout of university studies is a main concern in many countries, also for Health Sciences degrees. The reviews on dropout in all university degrees as well as nursing generally show multidimensional causes with factors related both to institutional and students' characteristics. Regarding the personal variables of students, researchers have focused on financial, family and personality features. Far less attention has been devoted to emotional variables. This study aims to explore whether individual variables of the emotional domain such as perceived emotional intelligence, dispositional optimism/pessimism and depressive rumination are related and/or can predict students' intention to dropout and academic performance. Using a cross-correlational approach, data were obtained from a sample of 144 nursing students. Students with a pessimistic disposition revealed a greater tendency to drop out. The remaining variables correlated significantly with pessimism but had no predictive value on dropout. Our results suggest that students with low levels of emotional clarity and repair and high depressive rumination have pessimistic expectations, so they are more likely to leave studies. No significant results were found in relation to academic performance. We conclude with an identification of strategies to increase retention and academic success. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. A comparison of outer electron radiation belt dropouts during solar ...

    Indian Academy of Sciences (India)

    O Ogunjobi

    2017-06-06

    Jun 6, 2017 ... study identifies radiation belt electron dropouts which are ultimately triggered when solar wind stream interfaces (SI) arrived at ... (Plasmapause); indicating a combination of electron cyclotron harmonic (ECH) and whistler mode waves as the contributing ... density known as the slot (Van-Allen 1959). Elec-.

  4. Drop-out from parenting training programmes: a retrospective study ...

    African Journals Online (AJOL)

    Objective:Parent training programmes are a well-established treatment approach for children and adolescents with disruptive behaviour disorders. However, dropout from treatment is a common problem that confounds research on the efficacy of this approach, and wastes important mental health resources. This study ...

  5. Immunization Dropout Rates in Ihe, Awgu Local Government Area ...

    African Journals Online (AJOL)

    of them lived in rural China, India, Indonesia or Nigeria.[17]. The dropout rates obtained in this study are very minimal. These low levels can be explained. It is seen that these villagers. Figure 1: A graphical representation of immunization coverage rate over 1 year period. Table 1: Immunization coverage using DPT. Month.

  6. Dropout Prevention Initiatives for Malaysian Indigenous Orang Asli Children

    Science.gov (United States)

    Nor, Sharifah Md; Roslan, Samsilah; Mohamed, Aminuddin; Hassan, Kamaruddin Hj. Abu; Ali, Mohamad Azhar Mat; Manaf, Jaimah Abdul

    2011-01-01

    This paper discusses dropout prevention initiatives by the Malaysian government for the disadvantaged indigenous Orang Asli people in the rural villages of Peninsular Malaysia. The roles of the Ministry of Education (MOE) as well as the Institutes of Teacher Education (ITEs) are highlighted pertaining to efforts at improving the quality of…

  7. A fast transient response low dropout regulator with current control methodology

    Energy Technology Data Exchange (ETDEWEB)

    Ma Zhuo; Guo Yang; Duan Zhikui; Xie Lunguo; Chen Jihua; Yu Jinshan, E-mail: guoyang@nudt.edu.cn [School of Computer, National University of Defense Technology, Changsha 410073 (China)

    2011-08-15

    A transient performance optimized CCL-LDO regulator is proposed. In the CCL-LDO, the control method of the charge pump phase-locked loop is adopted. A current control loop has the feedback signal and reference current to be compared, and then a loop filter generates the gate voltage of the power MOSFET by integrating the error current. The CCL-LDO has the optimized damping coefficient and natural resonant frequency, while its output voltage can be sub-1-V and is not restricted by the reference voltage. With a 1 {mu}F decoupling capacitor, the experimental results based on a 0.13 {mu}m CMOS process show that the output voltage is 1.0 V; when the workload changes from 100 {mu}A to 100 mA transiently, the stable dropout is 4.25 mV, the settling time is 8.2 {mu}s and the undershoot is 5.11 mV; when the workload changes from 100 mA to 100 {mu}A transiently, the stable dropout is 4.25 mV, the settling time is 23.3 {mu}s and the overshoot is 6.21 mV. The PSRR value is more than -95 dB. Most of the attributes of the CCL-LDO are improved rapidly with a FOM value of 0.0097.

  8. Predictors of school dropout among adolescents in Puerto Rico.

    Science.gov (United States)

    Calderón, José M; Robles, Rafaela R; Reyes, Juan C; Matos, Tomás D; Negrón, Juan L; Cruz, Miguel A

    2009-12-01

    This research aims to understand the circumstances associated with school dropout in a cohort of Puerto Rican adolescents. The study collected data from adolescents and their parents. Information related to school dropout among adolescents was obtained from the second year follow-up data from the longitudinal study funded by NIDA "Risky Families Embedded in Risky Environments" (Grant No. R01 DA 15301). Data was collected employing a self-administered and a face-to-face interview protocol. Prediction of school dropout was assessed throughout adolescent characteristics, family background, school experiences and behaviors. During the second follow-up, two years after the baseline assessment, approximately 6.2% of the adolescents reported dropping out from school. Logistic regression analysis indicates that older adolescents (OR = 6.6, 1.37-31.67), whose mother used drugs during pregnancy (OR = 4.9, 1.31-17.91), who reported high rates of absenteeism (OR = 4.8, 1.63-14.13), high school grade retention (OR = 3.7, 1.14-12.05), and attended school where teachers were attacked or wounded by students (O R =7.0, 1.44-34.17) were more likely to dropout of school. : These findings emphasize the need to further understand the effects of different elements of adolescents' environment such as family and school. It has been posited that dropping out of school is a process whose characteristics can be detected long before it occurs. The fact that students who dropout are more likely to report skip classes and grade retention can be relevant elements in prevention and early intervention for teachers and other school personnel.

  9. Predicting dropout in outpatient dialectical behavior therapy with patients with borderline personality disorder receiving psychiatric disability.

    Science.gov (United States)

    Landes, Sara J; Chalker, Samantha A; Comtois, Katherine Anne

    2016-01-01

    Rates of treatment dropout in outpatient Dialectical Behavior Therapy (DBT) in the community can be as high as 24 % to 58 %, making dropout a great concern. The primary purpose of this article was to examine predictors of dropout from DBT in a community mental health setting. Participants were 56 consumers with borderline personality disorder (BPD) who were psychiatrically disabled participating in a larger feasibility trial of Dialectical Behavior Therapy- Accepting the Challenges of Exiting the System. The following variables were examined to see whether they predicted dropout in DBT: age, education level, baseline level of distress, baseline level of non-acceptance of emotional responses, and skills module in which a consumer started DBT skills group. These variables were chosen based on known predictors of dropout in consumers with BPD and in DBT, as well as an interest in what naturally occurring variables might impact dropout. The dropout rate in this sample was 51.8 %. Results of the logistic regression show that younger age, higher levels of baseline distress, and a higher level of baseline non-acceptance of emotional responses were significantly associated with dropout. The DBT skills module in which an individual started group did not predict dropout. The implications of these findings are that knowledge of consumer age and pretreatment levels of distress and non-acceptance of emotional responses can impact providers' choice of commitment and treatment strategies to reduce dropout. Future research should examine these strategies, as well as the impact of predictor variables on outcome and reasons for dropout.

  10. The Relation of Dropout Prevention Programs in West Virginia Schools to Dropout Rates and Principal Perceptions of Effectiveness

    Science.gov (United States)

    Cline, Vicky Callison

    2016-01-01

    This study used non-experimental survey research to gather data on the kinds of dropout prevention programs in place in West Virginia high schools in 2014-15 and to evaluate their effectiveness based on possible relationships between principals' perceptions of the programs and graduation rates. The study focused on nine of 15 effective strategies…

  11. Folk High Schools and Dropouts from Upper Secondary School: Effects of Non-Academic Investments in Dropouts

    Science.gov (United States)

    Borgen, Solveig T.; Borgen, Nicolai T.

    2015-01-01

    High dropout rates from upper secondary school are related to substantial societal costs, and are hence a major policy concern. The Norwegian folk high schools provide a non-academic education in an intimate and nurturing environment where interpersonal and social skills are emphasised, and where individuals grow in sense of self-esteem and sense…

  12. DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/?-catenin signaling

    OpenAIRE

    Martin, Pierre-Marie; Stanley, Robert E.; Ross, Adam P.; Freitas, Andiara E.; Moyer, Caitlin E.; Brumback, Audrey C.; Iafrati, Jillian; Stapornwongkul, Kristina S.; Dominguez, Sky; Kivimäe, Saul; Mulligan, Kimberly A.; Pirooznia, Mehdi; McCombie, W. Richard; Potash, James B.; Zandi, Peter P.

    2016-01-01

    Mice lacking DIX domain containing-1 (DIXDC1), an intracellular Wnt/β-catenin signal pathway protein, have abnormal measures of anxiety, depression and social behavior. Pyramidal neurons in these animals’ brains have reduced dendritic spines and glutamatergic synapses. Treatment with lithium or a Glycogen Synthase Kinase-3 (GSK3) inhibitor corrects behavioral and neurodevelopmental phenotypes in these animals. Analysis of DIXDC1 in over 9,000 cases of autism, bipolar disorder and schizophreni...

  13. Physical exercise in treatment of AUDs – a dropout study

    DEFF Research Database (Denmark)

    Sari, Sengül; Roessler, Kirsten Kaya

    understanding of lived lives of dropouts from The Healthy Lifestyle Study, a qualitative interview study was conducted. Objective: This interview study aims to gain better understanding of and more in depth knowledge about how alcohol patients experience, think and feel about physical exercise when...... they are in treatment for alcohol use disorders. Methods: 15 semi structured interviews conducted with dropout patients from the Healthy Lifestyle Study. An interview guide with a phenomenological approach has been used. The interviews are taped and transcribed. Interpretative reading and systematic coding will be used...... as analytical tools. Results: We are in the process of analyzing, why results will be presented at the conference. Discussion: Patients drop out from intervention studies for several reasons. In this study we will categorize different types of reasons. Furthermore we will gain knowledge about how patients...

  14. Data-driven system to predict academic grades and dropout

    Science.gov (United States)

    Rovira, Sergi; Puertas, Eloi

    2017-01-01

    Nowadays, the role of a tutor is more important than ever to prevent students dropout and improve their academic performance. This work proposes a data-driven system to extract relevant information hidden in the student academic data and, thus, help tutors to offer their pupils a more proactive personal guidance. In particular, our system, based on machine learning techniques, makes predictions of dropout intention and courses grades of students, as well as personalized course recommendations. Moreover, we present different visualizations which help in the interpretation of the results. In the experimental validation, we show that the system obtains promising results with data from the degree studies in Law, Computer Science and Mathematics of the Universitat de Barcelona. PMID:28196078

  15. New Approach to reduce High School Dropout Rates

    Directory of Open Access Journals (Sweden)

    Mauricio Cristhian Portillo-Torres

    2015-05-01

    Full Text Available From 2006 to 2014, the Ministry of Public Education of Costa Rica implemented four strategic actions to reduce high school dropout rates. The main purpose of these actions was to promote student participation and student identification with their school. Studies prepared by the Ministry of Education and the Comptroller of the Republic were revised to assess the impact of these actions. The result of these actions does not show an actual decrease in the number of students who leave high school. Therefore, a more holistic view is necessary to ensure the students’ stay. This review suggests using use the concept of student engagement and applying a three tier system-wide dropout preventive actions: universal, targeted and intensive.

  16. GENDER STEREOTYPES IN THE SCHOOL DROPOUT: CASE EL FUERTE, SINALOA

    Directory of Open Access Journals (Sweden)

    Rosalva Ruíz-Ramírez

    2014-07-01

    Full Text Available Gender stereotypes are accepted preconceptions of what should be a man and a woman. Affect all areas of life, in the relationships that stablished in the family and the school. Within education, these stereotypes are reflected in the access, retention and completion of education degrees, as well as the area of study that preferred the women and men. They also have different effects on the causes of dropout depending on the gender to which they belong. This article aims to show the influence of gender stereotypes on dropout students and high school students in rural areas, specifically in three schools located in the municipality of El Fuerte, Sinaloa, the academic unit (AU San Blas and its extensions La Constancia and Las Higueras of Los Natoches. The results were obtained through a wider investigation in 2013.

  17. Back-dropout Transfer Learning for Action Recognition

    DEFF Research Database (Denmark)

    Ren, Huamin; Kanhabua, Nattiya; Møgelmose, Andreas

    2017-01-01

    Transfer learning aims at adapting a model learned from source dataset to target dataset. It is a beneficial approach especially when annotating on the target dataset is expensive or infeasible. Transfer learning has demonstrated its powerful learning capabilities in various vision tasks. Despite...... transfer learning being a promising approach, it is still an open question how to adapt the model learned from the source dataset to the target dataset. One big challenge is to prevent the impact of category bias on classification performance. Dataset bias exists when two images from the same category......, but from different datasets, are not classified as the same. To address this problem, we propose a transfer learning algorithm which takes advantage of misclassified images and applies back-dropout strategy to punish errors. We call this Negative Back-dropout Transfer Learning (NB-TL). Experimental results...

  18. The Return to College: Selection Bias and Dropout Risk

    OpenAIRE

    Hendricks, Lutz; Leukhina, Oksana

    2014-01-01

    We study two long-standing questions: (i) What part of the measured return to education is due to selection? (ii) The ex post return to schooling is higher than the return to most financial assets. How large are the contributions of various frictions to the "high" return to schooling? We focus in particular on the roles of college dropout risk, borrowing constraints, and learning about ability. We develop and calibrate a model of school choice. Key model features are: (i) ability heterogeneit...

  19. A multinomial logit model of college stopout and dropout behavior

    OpenAIRE

    Stratton, Leslie Sundt; O'Toole, Dennis M.; James N. Wetzel

    2005-01-01

    Studies of college attrition typically assume that all attrition is permanent. We use data from the 1990/94 Beginning Postsecondary Survey to distinguish between long-term dropout and short-term stopout behavior in order to test that assumption. We find significant differences between those who stop out and those who drop out in the first year. Failure to recognize these differences biases the results of standard attrition models and hence may cause policy makers to pursue inappropriate polic...

  20. College Enrollment, Dropouts and Option Value of Education

    OpenAIRE

    Nicholas Trachter; Ali Ozdagli

    2008-01-01

    Psychic costs are the most important component of the papers that are trying to match empirical facts related with college enrollment and dropout decisions of high school graduates. The absense of psychic cost requires very high levels of risk aversion to duplicate the same facts. However, psychic costs lack any economic meaning and treated as an obscure idiosyncratic component of utility function in influential papers such as Keane and Wolpin (1997) and Carneiro, Hansen, Heckman (2003). In t...

  1. Marijuana Use and High School Dropout: The Influence of Unobservables

    OpenAIRE

    McCaffrey, Daniel F.; Rosalie Liccardo Pacula; Bing Han; Phyllis Ellickson

    2010-01-01

    In this study we reconsider the relationship between heavy and persistent marijuana use and high school dropout status using a unique prospective panel study of over 4500 7th grade students from South Dakota who are followed up through high school. Propensity score weighting is used to adjust for baseline differences that are found to exist before marijuana initiation occurs (7th grade). Weighted logistic regression incorporating these propensity score weights is then used to examine the exte...

  2. Risk Psychosocial Factors to School Dropout and Early Teenage Pregnancy

    Directory of Open Access Journals (Sweden)

    Fabián Antonio Dávila Ramírez

    2016-01-01

    Full Text Available To explore the frequency and weight that psychosocial risk factors predispose to outcomes of early pregnancy and scholar dropout, a descriptive review was conducted. Materials and Meth­ods: A search and review of the results reported by observational studies in the PubMed data­base indexed from July 27, 2010 until July 25, 2013 was performed, restricting the search to studies in humans, Spanish or English written, not made in countries in Africa or Asia. Search was widened to LILACS database for the years 2006 to 2013 for Latinamerican countries. For inclusion, all case-control studies comparing different types of interventions and psychosocial risk factors in adolescents were eligible. Results: The review suggests violence experienced dur­ing adolescence, sexual abuse, belonging to a low socioeconomic status, low self-esteem, eating behavior disorders, smoking, alcoholism and drug addiction, mental disorders, early initiation of sex, poor family ties, lack of access to information, and resources for family planning as main psychosocial factors related to early pregnancy and scholar dropout in adolescents. Conclusions: Both risk factors associated with pregnancy and scholar dropout were described, and interven­tions targeting the described risk factors could potentially contribute to the reduction of these outcomes were described.

  3. Academic dropout or academic success: a model for prediction.

    Science.gov (United States)

    Kegel-Flom, P

    1986-09-01

    Why do some students who qualify for admission to optometry school become academic dropouts while others succeed? This question was addressed in a study which compared the admission records of 21 academic dropouts from three classes at the University of Houston College of Optometry (UHCO) with 269 retained students. Academic dropouts were found to have significantly lower preoptometry grades, lower Optometry College Admission Test (OCAT) scores, attended less competitive (i.e., less selective) undergraduate institutions, scored lower on the California Psychological Inventory (CPI), and were older than retained students. When these differentiating admission variables, excepting age, were applied to a new entering class, prediction of subsequent academic dismissal or serious academic difficulty was highly accurate. However, it was found that such prediction must take into account not only areas of weakness, i.e., academic and psychological factors which place a student at risk, but also areas of strength which give the student an advantage. For all students, regardless of age, sex, or ethnic origin, it was the ratio of "advantage" factors to "risk" factors which gave the most valid prediction of academic success or failure.

  4. A case study into the causes of school dropout

    Directory of Open Access Journals (Sweden)

    Gabriela Chirteş

    2010-01-01

    Full Text Available School dropout leads to failure in social integration, and as a result greatly diminishes aperson’s chances to achieve personal success in legally accepted fields of activity. The preventionand reduction of this phenomenon are extremely difficult to achieve due to the high complexity ofits causes. Research that has been carried out into this problem leads to the conclusion that therehas been an increase in the number of students facing school adjustment problems and it alsoattempts to answer the question whether there has been a real increase in the number of dropouts orif the situation should be put down to a series of very different and complex factors.A just identification and analysis of these factors would help reveal the action to be taken andeventually lead to a decrease and prevention of school dropout.Apart from the ineffectiveness of social policies in our country, a successful result of such anintervention would be the result of the joint efforts of a multi-curricular approach, involvement ofsocial institutions and team work.

  5. Dropout of a multidisciplinary treatment program for women with fibromyalgia

    Directory of Open Access Journals (Sweden)

    Tatiana Rehder Gonçalves

    2010-03-01

    Full Text Available Objective: To evaluate the dropout of a multidisciplinary treatment program in fibromyalgia (FM. Methods: An observational study conducted during the period of April 2000 to December 2005, including 133 women with fibromyalgia, participating in a multidisciplinary treatment program. Those who had left the treatment for two weeks or more were classified as inactive and contacted by telephone to record the reasons for their noncompliance, which were divided into four groups: 1 Family; 2 Occupations; 3 Medical; 4 Other Reasons. Results: When collecting data, 92 (69.4% women were considered inactive. There was no significant difference between noncompliance before and after six months of treatment. Of the total number of inactive women, 54 (40.8% participants left for medical reasons, 30 (22.6% for other reasons, 26 (19.4% for family reasons and 23 (17.2% due to occupation. There was no statistical difference between the motives of dropout according to the length of stay in the program (p> 0.05. Conclusion: We conclude that the multidisciplinary program for women with fibromyalgia had high levels of noncompliance, half of them occurred in the first six months. Among the main reasons reported for dropout, the medical reasons were more frequent.

  6. DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling.

    Science.gov (United States)

    Martin, P-M; Stanley, R E; Ross, A P; Freitas, A E; Moyer, C E; Brumback, A C; Iafrati, J; Stapornwongkul, K S; Dominguez, S; Kivimäe, S; Mulligan, K A; Pirooznia, M; McCombie, W R; Potash, J B; Zandi, P P; Purcell, S M; Sanders, S J; Zuo, Y; Sohal, V S; Cheyette, B N R

    2016-10-18

    Mice lacking DIX domain containing-1 (DIXDC1), an intracellular Wnt/β-catenin signal pathway protein, have abnormal measures of anxiety, depression and social behavior. Pyramidal neurons in these animals' brains have reduced dendritic spines and glutamatergic synapses. Treatment with lithium or a glycogen synthase kinase-3 (GSK3) inhibitor corrects behavioral and neurodevelopmental phenotypes in these animals. Analysis of DIXDC1 in over 9000 cases of autism, bipolar disorder and schizophrenia reveals higher rates of rare inherited sequence-disrupting single-nucleotide variants (SNVs) in these individuals compared with psychiatrically unaffected controls. Many of these SNVs alter Wnt/β-catenin signaling activity of the neurally predominant DIXDC1 isoform; a subset that hyperactivate this pathway cause dominant neurodevelopmental effects. We propose that rare missense SNVs in DIXDC1 contribute to psychiatric pathogenesis by reducing spine and glutamatergic synapse density downstream of GSK3 in the Wnt/β-catenin pathway.Molecular Psychiatry advance online publication, 18 October 2016; doi:10.1038/mp.2016.184.

  7. Dropouts and Social Determinants of Health; Policy for the Prevention of School Dropout, Qualitative Study of the Causes and Interventions

    OpenAIRE

    Rahbari, Maryam; Hajnaghizadeh, Fatemeh; Damari, Behzad; Adhami, Behzad

    2014-01-01

    Background: Indicators of the level of education are the most important parameters influencing each country′s development. Social indicators considered to be a determinant of one′s health consists of two constituents namely; (1) Rate of students enrolled in elementary, guidance, secondary and higher education and (2) the rate of adult literacy. This study is aimed to evaluate the situation of school dropouts in Iran, their causes, and appropriate interventions. Methods: Data were collecte...

  8. Risk Factors for School Dropout in a Sample of Juvenile Offenders.

    Science.gov (United States)

    Fernández-Suárez, Asunción; Herrero, Juan; Pérez, Beatriz; Juarros-Basterretxea, Joel; Rodríguez-Díaz, Francisco J

    2016-01-01

    Backgrounds: The high rates of school dropout worldwide and their relevance highlight the need for a close study of its causes and consequences. Literature has suggested that school dropout might be explained by multiple causes at different levels (individual, family, school, and neighborhood). The aim of the current study is to examine the relation between individual (defiant attitude, irresponsibility, alcohol abuse, and illegal drugs use), family (educational figure absent and parental monitoring), school factors (truancy and school conflict) and school dropout. Method: Judicial files of all juvenile offenders (218 males and 46 females) with a judicial penal measure in Asturias (Spain) in the year 2012 were examined. Multivariate logistic regression analyses were performed to estimate the relationships between school dropout and individual, family and school variables. Results: As for the individual characteristics, results showed that school dropouts were more irresponsible than non-dropouts. Also they had higher rates of illegal drug use and alcohol abuse. Moreover, lack of parental monitoring emerged as a key predictive factor of school dropout, beyond the type of family structure in terms of the presence of both or only one educational figure. Finally, school factors did not show a significant relationship to school dropout. Conclusions : These findings indicate that school dropout is a multidimensional process. School and family policies that emphasize the role of parental monitoring and prevent alcohol and substance abuse are recommended.

  9. Risk Factors for School Dropout in a Sample of Juvenile Offenders

    Science.gov (United States)

    Fernández-Suárez, Asunción; Herrero, Juan; Pérez, Beatriz; Juarros-Basterretxea, Joel; Rodríguez-Díaz, Francisco J.

    2016-01-01

    Backgrounds: The high rates of school dropout worldwide and their relevance highlight the need for a close study of its causes and consequences. Literature has suggested that school dropout might be explained by multiple causes at different levels (individual, family, school, and neighborhood). The aim of the current study is to examine the relation between individual (defiant attitude, irresponsibility, alcohol abuse, and illegal drugs use), family (educational figure absent and parental monitoring), school factors (truancy and school conflict) and school dropout. Method: Judicial files of all juvenile offenders (218 males and 46 females) with a judicial penal measure in Asturias (Spain) in the year 2012 were examined. Multivariate logistic regression analyses were performed to estimate the relationships between school dropout and individual, family and school variables. Results: As for the individual characteristics, results showed that school dropouts were more irresponsible than non-dropouts. Also they had higher rates of illegal drug use and alcohol abuse. Moreover, lack of parental monitoring emerged as a key predictive factor of school dropout, beyond the type of family structure in terms of the presence of both or only one educational figure. Finally, school factors did not show a significant relationship to school dropout. Conclusions: These findings indicate that school dropout is a multidimensional process. School and family policies that emphasize the role of parental monitoring and prevent alcohol and substance abuse are recommended. PMID:28082934

  10. The effect of Deficient Muscarinic Signaling on Commonly Reported Biochemical Effects in Schizophrenia and Convergence with Genetic Susceptibility Loci in explaining symptom dimensions of psychosis.

    Directory of Open Access Journals (Sweden)

    Costa eVakalopoulos

    2014-12-01

    Full Text Available With the advent of DSM 5 criticism has generally centred on a lack of biological validity of the diagnostic criteria. Part of the problem in describing a nosology of psychosis is the tacit assumption of multiple genetic causes each with an incremental loading on the clinical picture that fails to differentiate a clear underlying pathophysiology of high impact. The aim of this paper is to consolidate a primary theory of deficient muscarinic signalling underlying key clinical features of schizophrenia and its regulation by several important genetic associations including neuregulin, DISC and dysbindin. Secondary reductions in markers for GABAergic function and changes in the levels of interneuron calcium binding proteins parvalbumin and calbindin can be attributed to dysfunctional muscarinic transduction. A parallel association exists for cytokine production. The convergent pathway hypothesis is likewise used to model dopaminergic and glutamatergic theories of schizophrenia. The negative symptom dimension is correlated with dysfunction of Akt and ERK transduction, a major point of convergence. The present paradigm predicts the importance of a recent finding of a deletion in a copy number variant of PLCB1 and its potential use if replicated, as one of the first testable biological markers differentiating schizophrenia from bipolar disorder and further subtyping of schizophrenia into deficit and non-deficit. Potential limitations of PLCB1 as a prospective marker are also discussed.

  11. Alternative education programmes and middle school dropout in Honduras

    Science.gov (United States)

    Marshall, Jeffery H.; Aguilar, Claudia R.; Alas, Mario; Castellanos, Renán Rápalo; Castro, Levi; Enamorado, Ramón; Fonseca, Esther

    2014-05-01

    Honduras has made steady progress in expanding post-primary school coverage in recent years, but many rural communities still do not provide a middle (lower secondary) school. As a result, Honduras has implemented a number of middle school alternative programmes designed to meet the needs of at-risk populations throughout the country. This article analyses dropout in three of the four main alternative lower secondary school programmes in Honduras over a three-year period for a cohort of roughly 5,500 students. The results show that these programmes are indeed reaching a vulnerable population in the country, but dropout rates are generally very high - upwards of 50 per cent in some cases - between Grades 7 and 9. Furthermore, even in the control school comparison samples made up of formal lower secondary schools, about 25 per cent of children leave school between Grades 7 and 9. The authors' analysis includes propensity score matching (PSM) methods that make more focused comparisons between students in alternative programmes and control samples. These results show that dropout rates in alternative programmes are not much different than in control schools, and only significant in one programme comparison, when taking into account family background characteristics like socioeconomic status (SES). Multivariate analysis within alternative programme samples finds that attrition is lower in those learning centres which have adopted key features of formal schools, such as university-educated teachers. The results highlight the tremendous variation in the alternative middle school sector in terms of programme features, school quality and student outcomes, as well as the challenges of expanding this sector to meet the growing demand for lower secondary schooling in Honduras.

  12. GENDER STEREOTYPES IN THE SCHOOL DROPOUT: CASE EL FUERTE, SINALOA

    OpenAIRE

    Rosalva Ruíz-Ramírez; María del Rosario Ayala-Carrillo; Emma Zapata-Martelo

    2014-01-01

    Gender stereotypes are accepted preconceptions of what should be a man and a woman. Affect all areas of life, in the relationships that stablished in the family and the school. Within education, these stereotypes are reflected in the access, retention and completion of education degrees, as well as the area of study that preferred the women and men. They also have different effects on the causes of dropout depending on the gender to which they belong. This article aims to show the influence o...

  13. Finishing high school: alternative pathways and dropout recovery.

    Science.gov (United States)

    Tyler, John H; Lofstrom, Magnus

    2009-01-01

    John Tyler and Magnus Lofstrom take a close look at the problems posed when students do not complete high school. The authors begin by discussing the ongoing, sometimes heated, debate over how prevalent the dropout problem is. They note that one important reason for discrepancies in reported dropout rates is whether holders of the General Educational Development (GED) credential are counted as high school graduates. The authors also consider the availability of appropriate student data. The overall national dropout rate appears to be between 22 and 25 percent, but the rate is higher among black and Hispanic students, and it has not changed much in recent decades. Tyler and Lofstrom conclude that schools are apparently doing about as well now as they were forty years ago in terms of graduating students. But the increasingly competitive pressures associated with a global economy make education ever more important in determining personal and national well-being. A student's decision to drop out of school, say the authors, is affected by a number of complex factors and is often the culmination of a long process of disengagement from school. That decision, not surprisingly, carries great cost to both the student and society. Individual costs include lower earnings, higher likelihood of unemployment, and greater likelihood of health problems. Because minority and low-income students are significantly more likely than well-to-do white students to drop out of school, the individual costs fall unevenly across groups. Societal costs include loss of tax revenue, higher spending on public assistance, and higher crime rates. Tyler and Lofstrom go on to survey research on programs designed to reduce the chances of students' dropping out. Although the research base on this question is not strong, they say, close mentoring and monitoring of students appear to be critical components of successful programs. Other dropout-prevention approaches associated with success are family

  14. Alaskan Native High School Dropouts: A Report Prepared for Project ANNA.

    Science.gov (United States)

    Jacobson, Desa

    Presented is a summary of the Alaskan Native high school dropouts. The data collected on 180 Native Alaskan high school dropouts was taken from the regional dormitories at Nome, Kodiak, Bethel and Boarding Home programs in Anchorage, Tok, Fairbanks, Dillingham, and Ketchikan. Students who terminated for academic reasons, failed to attend school,…

  15. Teachers' Opinions of Student Dropout from Formal Music Education Centres of the Canary Islands

    Science.gov (United States)

    Lorenzo Socorro, Sonia; Escandell Bermúdez, María Olga; Castro Sánchez, José Juan

    2016-01-01

    One hundred and eighty-five teachers were surveyed to determine their opinion of student dropout from formal music centres in the Canary Islands. The goal of the study was to investigate the causes of dropout and strategies to prevent it. Teachers' opinions were collected by means of a questionnaire. The influence of the environment on the…

  16. Predicting Different Types of School Dropouts: A Typological Approach with Two Longitudinal Samples.

    Science.gov (United States)

    Janosz, Michel; Le Blanc, Marc; Boulerice, Bernard; Tremblay, Richard E.

    2000-01-01

    Explores the heuristic value of a typological approach for preventing and studying school dropout. Empirically builds a typology of dropouts based on individual school experiences, tests the typology's reliability by replicating the classification with two different longitudinal samples, and examines the typology's predictive and discriminant…

  17. Electron–Ion Intensity Dropouts in Gradual Solar Energetic Particle Events during Solar Cycle 23

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Lun C., E-mail: ltan@umd.edu [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States)

    2017-09-01

    Since the field-line mixing model of Giacalone et al. suggests that ion dropouts cannot happen in the “gradual” solar energetic particle (SEP) event because of the large size of the particle source region in the event, the observational evidence of ion dropouts in the gradual SEP event should challenge the model. We have searched for the presence of ion dropouts in the gradual SEP event during solar cycle 23. From 10 SEP events the synchronized occurrence of ion and electron dropouts is identified in 12 periods. Our main observational facts, including the mean width of electron–ion dropout periods being consistent with the solar wind correlation scale, during the dropout period the dominance of the slab turbulence component and the enhanced turbulence power parallel to the mean magnetic field, and the ion gyroradius dependence of the edge steepness in dropout periods, are all in support of the solar wind turbulence origin of dropout events. Also, our observation indicates that a wide longitude distribution of SEP events could be due to the increase of slab turbulence fraction with the increased longitude distance from the flare-associated active region.

  18. Meta-Analyses of Ethnic Match as a Predictor of Dropout, Utilization, and Level of Functioning.

    Science.gov (United States)

    Maramba, Gloria Gia; Hall, Gordon C. Nagayama

    2002-01-01

    Meta-analyses were performed on seven studies of ethnic match and psychotherapy. Results reveal a small dropout and utilization effect sizes, indicating that ethnic match is not a significant clinical predictor of decreasing dropout after the first session or increasing number of sessions attended. (Contains references and tables.) (GCP)

  19. Another Way out: The Impact of Juvenile Arrests on High School Dropout

    Science.gov (United States)

    Hirschfield, Paul

    2009-01-01

    This article suggests that contact with the legal system increased school dropout in a Chicago sample of 4,844 inner-city students. According to multilevel multivariate logistic models, students who were first arrested during the 9th or 10th grade were six to eight times more likely than were nonarrested students ever to dropout of high school and…

  20. Basic school dropout in Ghana: a case study of the Amansie West ...

    African Journals Online (AJOL)

    In view of the increasing cost of education the persistent phenomenon of school dropout has become a constant worry to all stakeholders. The focus of this paper was to assess the trend of basic school dropout in Amansie West, a predominantly rural district in Ghana and to further determine the main causes and policy ...

  1. A Tripartite Perspective of Social Capital and Its Access by High School Dropouts

    Science.gov (United States)

    Drewry, Julie A.; Burge, Penny L.; Driscoll, Lisa G.

    2010-01-01

    The purpose of this phenomenological study was to document and analyze students' experiences with dropping out of high school, using a social capital framework. Examining the stories of high school dropouts provided valuable information related to the root causes of dropout behaviors. The context of this study was a high school in an urban school…

  2. Dimensions Of Basic School Dropouts In Rural Ghana: The Case Of ...

    African Journals Online (AJOL)

    The objective of this paper was to investigate the various dimensions of basic school dropouts in rural Ghana using the Asutifi district as a case study. The analysis of data (both quantitative and qualitative) gathered from several stakeholders of basic education in the district, revealed that the causes of school dropout were ...

  3. Changing Pattern and Process of High School Dropouts between 1980s and 2000s

    Science.gov (United States)

    Suh, Suhyun; Suh, Jingyo

    2011-01-01

    There has been a general decline in the dropout rate and an increase in the high school completion rate over the last three decades. This research investigates causes for the decline in the dropout rate over the periods using decomposition analysis. Traditional cross-section analysis was inadequate to perform this task. Using the two cohort…

  4. An Examination of Compulsory School Attendance Ages and High School Dropout and Completion

    Science.gov (United States)

    Landis, Rebecca N.; Reschly, Amy L.

    2011-01-01

    An increasingly popular, but underresearched, initiative aimed at reducing high school dropout is raising the compulsory school attendance age. This study used a national data set from academic years 2001-02 to 2005-06 to examine the grade level at which students drop out, rates of dropout over time, and high school completion by state, region of…

  5. Evaluation of a Public Awareness Campaign to Prevent High School Dropout.

    Science.gov (United States)

    Babinski, Leslie M; Corra, Ashley J; Gifford, Elizabeth J

    2016-08-01

    Many advocacy organizations devote time and resources to increasing community awareness and educating the public in an effort to gain support for their issue. One such effort, the Dropout Prevention Campaign by America's Promise Alliance, aimed to increase the visibility of the high school dropout problem and mobilize the community to take action. The objective of this paper is to evaluate the framing of the Dropout Prevention Campaign in television news media. To evaluate this campaign, television news coverage about high school dropout in 12 U.S. communities (N = 982) was examined. A content analysis of news transcripts was conducted and coded to determine the definition of the problem, the reasons for dropout and the possible solutions. Findings indicated that the high school dropout problem was most often framed (30 % of news segments) in terms of the economic and societal implications for the community. Individual student factors as well as broader societal influences were frequently discussed as possible reasons for dropout. The most commonly mentioned solutions were school-based interventions. News segments that mentioned America's Promise Alliance were more likely to frame the issue as a crisis and to use statistics to illustrate that point. Solutions that were more likely to appear in America's Promise segments promoted community and cross-sector involvement, consistent with the messages promoted by the Dropout Prevention Campaign. The findings suggest that a media content analysis can be an effective framework for analyzing a prevention campaign.

  6. The Meaning of School from Dropout's View Point (A Phenomenological Study)

    Science.gov (United States)

    Habibi; Setiawan, Cally

    2017-01-01

    Student dropouts are complex problems in Indonesia. Some of the dropouts living in rural areas have migrated to the large cities. It contributes to the child labor growth which is already one the major problems in Indonesia. Knowledge about the meaning of school from their perspective could be helpful for policy and programs related to dropout…

  7. Why Wait? Early Determinants of School Dropout in Preventive Pediatric Primary Care

    NARCIS (Netherlands)

    Theunissen, M.J.; Bosma, H.; Verdonk, P.; Feron, F.

    2015-01-01

    Background To answer the question of what bio-psychosocial determinants in infancy, early and middle childhood, and adolescence predict school drop-out in young adulthood, we approached the complex process towards school dropout as a multidimensional, life-course phenomenon. The aim is to find signs

  8. Switching Schools: Revisiting the Relationship between School Mobility and High School Dropout

    Science.gov (United States)

    Gasper, Joseph; DeLuca, Stefanie; Estacion, Angela

    2012-01-01

    Youth who switch schools are more likely to demonstrate a wide array of negative behavioral and educational outcomes, including dropping out of high school. However, whether switching schools actually puts youth at risk for dropout is uncertain, since youth who switch schools are similar to dropouts in their levels of prior school achievement and…

  9. An Overview of School Dropout in Central America: Unresolved Issues and New Challenges for Education Progress

    Science.gov (United States)

    Adelman, Melissa A.; Székely, Miguel

    2017-01-01

    School dropout is a growing concern in Central America, and in Latin America as a whole, because of its consequences for economic productivity, the inclusiveness of growth, social cohesion, and increasing youth risks. This paper utilizes more than two decades of household survey data to construct a systematic overview of school dropout at the…

  10. Dropout in the lower tracks of Dutch secondary education : Predictor variables and variation among schools

    NARCIS (Netherlands)

    Luyten, H; Bosker, R.J.; Dekkers, H; Derks, A

    2003-01-01

    This study analyses the data from a large-scale longitudinal investigation into the effect of both school and student characteristics on the dropout rate for students in lower secondary education in The Netherlands. Dropout rates were found to vary significantly between schools, but only a single

  11. Oregon's High School Dropouts: Examining the Economic and Social Costs. Research Brief

    Science.gov (United States)

    Foundation for Educational Choice, 2010

    2010-01-01

    The Foundation for Educational Choice recently commissioned a new study to examine the economic and social costs of Oregon's high school dropouts. Emily House, the study's author, analyzed how dropouts in the state dramatically impact state finances through reduced tax revenues, increased Medicaid costs, and high incarceration rates. House's study…

  12. Extracurricular Participation, "At-Risk" Status, and the High School Dropout Decision

    Science.gov (United States)

    Crispin, Laura M.

    2017-01-01

    I estimate the effect of extracurricular participation on the high school dropout decision with a particular focus on at-risk students. Using a sample of tenth grade students from the National Education Longitudinal Study of 1988, I jointly estimate the dropout and participation decisions (including extracurricular offerings per student), and…

  13. Stressors and Turning Points in High School and Dropout: A Stress Process, Life Course Framework

    Science.gov (United States)

    Dupéré, Véronique; Leventhal, Tama; Dion, Eric; Crosnoe, Robert; Archambault, Isabelle; Janosz, Michel

    2015-01-01

    High school dropout is commonly seen as the result of a long-term process of failure and disengagement. As useful as it is, this view has obscured the heterogeneity of pathways leading to dropout. Research suggests, for instance, that some students leave school not as a result of protracted difficulties but in response to situations that emerge…

  14. Keeping Students on Track to Graduate: A Synthesis of School Dropout Trends, Prevention, and Intervention Initiatives

    Science.gov (United States)

    Ecker-Lyster, Meghan; Niileksela, Christopher

    2016-01-01

    This article reviews the literature on dropout trends, prevention, and intervention initiatives for school-aged children. Theoretical and consequential trends are highlighted to offer educators a perspective in which to view the dropout problem. This article also examines current trends in prevention and intervention initiatives aimed at reducing…

  15. Predicting Dropout Using Student- and School-Level Factors: An Ecological Perspective

    Science.gov (United States)

    Wood, Laura; Kiperman, Sarah; Esch, Rachel C.; Leroux, Audrey J.; Truscott, Stephen D.

    2017-01-01

    High school dropout has been associated with negative outcomes, including increased rates of unemployment, incarceration, and mortality. Dropout rates vary significantly depending on individual and environmental factors. The purpose of our study was to use an ecological perspective to concurrently explore student- and school-level predictors…

  16. Evidence That Classroom-Based Behavioral Interventions Reduce Pregnancy-Related School Dropout among Nairobi Adolescents

    Science.gov (United States)

    Sarnquist, Clea; Sinclair, Jake; Omondi Mboya, Benjamin; Langat, Nickson; Paiva, Lee; Halpern-Felsher, Bonnie; Golden, Neville H.; Maldonado, Yvonne A.; Baiocchi, Michael T.

    2017-01-01

    Purpose: To evaluate the effect of behavioral, empowerment-focused interventions on the incidence of pregnancy-related school dropout among girls in Nairobi's informal settlements. Method: Retrospective data on pregnancy-related school dropout from two cohorts were analyzed using a matched-pairs quasi-experimental design. The primary outcome was…

  17. Factors associated with dropout from treatment for eating disorders: a comprehensive literature review

    Directory of Open Access Journals (Sweden)

    Tomba Elena

    2009-10-01

    Full Text Available Abstract Background Dropout (DO is common in the treatment of eating disorders (EDs, but the reasons for this phenomenon remain unclear. This study is an extensive review of the literature regarding DO predictors in EDs. Methods All papers in PubMed, PsycINFO and Cochrane Library (1980-2009 were considered. Methodological issues and detailed results were analysed for each paper. After selection according to inclusion criteria, 26 studies were reviewed. Results The dropout rates ranged from 20.2% to 51% (inpatient and from 29% to 73% (outpatient. Predictors of dropout were inconsistent due to methodological flaws and limited sample sizes. There is no evidence that baseline ED clinical severity, psychiatric comorbidity or treatment issues affect dropout. The most consistent predictor is the binge-purging subtype of anorexia nervosa. Good evidence exists that two psychological traits (high maturity fear and impulsivity and two personality dimensions (low self-directedness, low cooperativeness are related to dropout. Conclusion Implications for clinical practice and areas for further research are discussed. Particularly, these results highlight the need for a shared definition of dropout in the treatment of eating disorders for both inpatient and outpatient settings. Moreover, the assessment of personality dimensions (impulse control, self-efficacy, maturity fear and others as liability factors for dropout seems an important issue for creating specific strategies to reduce the dropout phenomenon in eating disorders.

  18. Factors associated with dropout from treatment for eating disorders: a comprehensive literature review.

    Science.gov (United States)

    Fassino, Secondo; Pierò, Andrea; Tomba, Elena; Abbate-Daga, Giovanni

    2009-10-09

    Dropout (DO) is common in the treatment of eating disorders (EDs), but the reasons for this phenomenon remain unclear. This study is an extensive review of the literature regarding DO predictors in EDs. All papers in PubMed, PsycINFO and Cochrane Library (1980-2009) were considered. Methodological issues and detailed results were analysed for each paper. After selection according to inclusion criteria, 26 studies were reviewed. The dropout rates ranged from 20.2% to 51% (inpatient) and from 29% to 73% (outpatient). Predictors of dropout were inconsistent due to methodological flaws and limited sample sizes. There is no evidence that baseline ED clinical severity, psychiatric comorbidity or treatment issues affect dropout. The most consistent predictor is the binge-purging subtype of anorexia nervosa. Good evidence exists that two psychological traits (high maturity fear and impulsivity) and two personality dimensions (low self-directedness, low cooperativeness) are related to dropout. Implications for clinical practice and areas for further research are discussed. Particularly, these results highlight the need for a shared definition of dropout in the treatment of eating disorders for both inpatient and outpatient settings. Moreover, the assessment of personality dimensions (impulse control, self-efficacy, maturity fear and others) as liability factors for dropout seems an important issue for creating specific strategies to reduce the dropout phenomenon in eating disorders.

  19. Leadership to Success: A Study of the Leadership Behaviors of Dropout Recovery Program Leaders

    Science.gov (United States)

    Turner, William S.

    2010-01-01

    Little is known about the leadership practices and behaviors of the building leaders of dropout recovery schools and how these behaviors correlate with the ability of their student population to pass state-required standardized tests. This study analyzed the responses of 8 building leaders of dropout recovery schools regarding their leadership…

  20. The American Indian High School Dropout Rate: A Matter of Style?

    Science.gov (United States)

    Backes, John S.

    1993-01-01

    The Gregorc Style Delineator was administered to 358 graduates and dropouts from 2 matched, racially homogeneous white and Chippewa high schools in Minnesota. Dominant learning styles were abstract random for all Chippewa subjects and concrete sequential for all whites. No significant differences were found between Chippewa graduates and dropouts.…

  1. Treatment Dropout in Web-Based Cognitive Behavioral Therapy for Patients with Eating Disorders.

    NARCIS (Netherlands)

    ter Huurne, E.D.; Postel, Marloes Gerda; de Haan, H.A.; van der Palen, Jacobus Adrianus Maria; de Jong, C.A.

    2017-01-01

    Treatment dropout is an important concern in eating disorder treatments as it has negative implications for patients’ outcome, clinicians’ motivation, and research studies. Our main objective was to conduct an exploratory study on treatment dropout in a two-part web-based cognitive behavioral

  2. Treatment dropout in web-based cognitive behavioral therapy for patients with eating disorders

    NARCIS (Netherlands)

    Huurne, E.D. ter; Postel, M.G.; Haan, H.A. de; Palen, J.A.M. van der; Jong, C.A.J. de

    2017-01-01

    Treatment dropout is an important concern in eating disorder treatments as it has negative implications for patients' outcome, clinicians’ motivation, and research studies. Our main objective was to conduct an exploratory study on treatment dropout in a two-part web-based cognitive behavioral

  3. A Systematic Review of Dropout from Organized Sport among Children and Youth

    Science.gov (United States)

    Crane, Jeff; Temple, Viviene

    2015-01-01

    Leisure constraints theory was used as a framework to systematically review factors associated with dropout of organized sport among children and adolescents. Keyword searches for the population, context and construct of interest (i.e. dropout) identified articles from the entire contents of the following databases: Academic Search Complete, ERIC,…

  4. Investigating the Impact of Financial Aid on Student Dropout Risks: Racial and Ethnic Differences

    Science.gov (United States)

    Chen, Rong; DesJardins, Stephen L.

    2010-01-01

    This study focuses on the differences in college student dropout behavior among racial/ethnic groups. We employ event history methods and data from the Beginning Postsecondary Students (BPS) and National Postsecondary Student Aid Study (NPSAS) surveys to investigate how financial aid may differentially influence dropout risks among these student…

  5. Longitudinal drop-out and weighting against its bias.

    Science.gov (United States)

    Schmidt, Steffen C E; Woll, Alexander

    2017-12-08

    The bias caused by drop-out is an important factor in large population-based epidemiological studies. Many studies account for it by weighting their longitudinal data, but to date there is no detailed final approach for how to conduct these weights. In this study we describe the observed longitudinal bias and a three-step longitudinal weighting approach used for the longitudinal data in the MoMo baseline (N = 4528, 4-17 years) and wave 1 study with 2807 (62%) participants between 2003 and 2012. The most meaningful drop-out predictors were socioeconomic status of the household, socioeconomic characteristics of the mother and daily TV usage. Weighting reduced the bias between the longitudinal participants and the baseline sample, and also increased variance by 5% to 35% with a final weighting efficiency of 41.67%. We conclude that a weighting procedure is important to reduce longitudinal bias in health-oriented epidemiological studies and suggest identifying the most influencing variables in the first step, then use logistic regression modeling to calculate the inverse of the probability of participation in the second step, and finally trim and standardize the weights in the third step.

  6. Shifting problems and shifting policies to reduce student drop-out

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    2016-01-01

    vocational programmes. Consequently, lowering the drop-out rate is high on a policy maker’s agenda. This chapter examines the education policies designed to reduce the prevalence of drop-out in Denmark’s vocational system. First, the chapter reviews the international research on the phenomenon of drop......-out, as well as the policies that have been implemented in pursuit of improving student retention. The review identifies two pervasive ways in which the drop-out problem has been framed in both policy and research. The first locates the drop-out problem with individual students, while the second locates...... the problem with the educational system. This study of Danish vocational education policy examines both (i) how student attrition has been framed in different periods, and (ii) the solutions that have been prescribed in accordance with shifting conceptualisations of early school leaving. The author’s inquiry...

  7. Program specific admission testing and dropout for sports science students: a prospective cohort study

    DEFF Research Database (Denmark)

    O'Neill, Lotte; Christensen, Mette Krogh; Vonsild, Maria Cecilie

    2014-01-01

    Recent research in medical education suggests that program specific admission testing could have a protective effect against early dropout. Little is known about the effect of program specific admission testing on dropout in other areas of higher education. The aim of this paper was to examine if......-based admission. This result may fit with elements of previous dropout theory, student-environment fit theory and perhaps also with self-efficacy theory....... was multivariate logistic regression and predictors examined were: admission group (grade-based or admission tested) as well as educational and socio-demographic variables. The outcome was dropout within 2 years of study start. Admission testing offered superior protection against dropout compared to grade...

  8. A Comparative Study of Dropout Rates and Causes for Two Different Distance Education Courses

    Directory of Open Access Journals (Sweden)

    Christos Pierrakeas

    2004-08-01

    Full Text Available This paper reports the results of a survey conducted to examine the root causes leading to student dropout at a Greek distance education university. Data was gathered from two different courses – an undergraduate course leading to a Bachelors degree in Informatics (characterized by high dropout rates, and a postgraduate course leading to a Masters degree in education (characterized by low dropout rates. A comparative analysis of these two different courses revealed important similarities in dropout percentages and the reasons cited by students for dropping out. Our analysis also revealed important differences as well. This paper presents the results of a survey designed to investigate the relationship between dropout with intrinsic (student-related factors such as sickness, work/ school conflict etc., and extrinsic (institutional-related factors such as study methods and materials, educational approach, and tutor influence.

  9. Switching Schools: Reconsidering the Relationship Between School Mobility and High School Dropout.

    Science.gov (United States)

    Gasper, Joseph; DeLuca, Stefanie; Estacion, Angela

    2012-06-01

    Youth who switch schools are more likely to demonstrate a wide array of negative behavioral and educational outcomes, including dropping out of high school. However, whether switching schools actually puts youth at risk for dropout is uncertain, since youth who switch schools are similar to dropouts in their levels of prior school achievement and engagement, which suggests that switching schools may be part of the same long-term developmental process of disengagement that leads to dropping out. Using data from the National Longitudinal Survey of Youth 1997, this study uses propensity score matching to pair youth who switched high schools with similar youth who stayed in the same school. We find that while over half the association between switching schools and dropout is explained by observed characteristics prior to 9 th grade, switching schools is still associated with dropout. Moreover, the relationship between switching schools and dropout varies depending on a youth's propensity for switching schools.

  10. Switching Schools: Reconsidering the Relationship Between School Mobility and High School Dropout

    Science.gov (United States)

    Gasper, Joseph; DeLuca, Stefanie; Estacion, Angela

    2014-01-01

    Youth who switch schools are more likely to demonstrate a wide array of negative behavioral and educational outcomes, including dropping out of high school. However, whether switching schools actually puts youth at risk for dropout is uncertain, since youth who switch schools are similar to dropouts in their levels of prior school achievement and engagement, which suggests that switching schools may be part of the same long-term developmental process of disengagement that leads to dropping out. Using data from the National Longitudinal Survey of Youth 1997, this study uses propensity score matching to pair youth who switched high schools with similar youth who stayed in the same school. We find that while over half the association between switching schools and dropout is explained by observed characteristics prior to 9th grade, switching schools is still associated with dropout. Moreover, the relationship between switching schools and dropout varies depending on a youth's propensity for switching schools. PMID:25554706

  11. A Point Mutation in Suppressor of Cytokine Signalling 2 (Socs2) Increases the Susceptibility to Inflammation of the Mammary Gland while Associated with Higher Body Weight and Size and Higher Milk Production in a Sheep Model.

    Science.gov (United States)

    Rupp, Rachel; Senin, Pavel; Sarry, Julien; Allain, Charlotte; Tasca, Christian; Ligat, Laeticia; Portes, David; Woloszyn, Florent; Bouchez, Olivier; Tabouret, Guillaume; Lebastard, Mathieu; Caubet, Cécile; Foucras, Gilles; Tosser-Klopp, Gwenola

    2015-12-01

    Mastitis is an infectious disease mainly caused by bacteria invading the mammary gland. Genetic control of susceptibility to mastitis has been widely evidenced in dairy ruminants, but the genetic basis and underlying mechanisms are still largely unknown. We describe the discovery, fine mapping and functional characterization of a genetic variant associated with elevated milk leukocytes count, or SCC, as a proxy for mastitis. After implementing genome-wide association studies, we identified a major QTL associated with SCC on ovine chromosome 3. Fine mapping of the region, using full sequencing with 12X coverage in three animals, provided one strong candidate SNP that mapped to the coding sequence of a highly conserved gene, suppressor of cytokine signalling 2 (Socs2). The frequency of the SNP associated with increased SCC was 21.7% and the Socs2 genotype explained 12% of the variance of the trait. The point mutation induces the p.R96C substitution in the SH2 functional domain of SOCS2 i.e. the binding site of the protein to various ligands, as well-established for the growth hormone receptor GHR. Using surface plasmon resonance we showed that the p.R96C point mutation completely abrogates SOCS2 binding affinity for the phosphopeptide of GHR. Additionally, the size, weight and milk production in p.R96C homozygote sheep, were significantly increased by 24%, 18%, and 4.4%, respectively, when compared to wild type sheep, supporting the view that the point mutation causes a loss of SOCS2 functional activity. Altogether these results provide strong evidence for a causal mutation controlling SCC in sheep and highlight the major role of SOCS2 as a tradeoff between the host's inflammatory response to mammary infections, and body growth and milk production, which are all mediated by the JAK/STAT signaling pathway.

  12. A Point Mutation in Suppressor of Cytokine Signalling 2 (Socs2 Increases the Susceptibility to Inflammation of the Mammary Gland while Associated with Higher Body Weight and Size and Higher Milk Production in a Sheep Model.

    Directory of Open Access Journals (Sweden)

    Rachel Rupp

    2015-12-01

    Full Text Available Mastitis is an infectious disease mainly caused by bacteria invading the mammary gland. Genetic control of susceptibility to mastitis has been widely evidenced in dairy ruminants, but the genetic basis and underlying mechanisms are still largely unknown. We describe the discovery, fine mapping and functional characterization of a genetic variant associated with elevated milk leukocytes count, or SCC, as a proxy for mastitis. After implementing genome-wide association studies, we identified a major QTL associated with SCC on ovine chromosome 3. Fine mapping of the region, using full sequencing with 12X coverage in three animals, provided one strong candidate SNP that mapped to the coding sequence of a highly conserved gene, suppressor of cytokine signalling 2 (Socs2. The frequency of the SNP associated with increased SCC was 21.7% and the Socs2 genotype explained 12% of the variance of the trait. The point mutation induces the p.R96C substitution in the SH2 functional domain of SOCS2 i.e. the binding site of the protein to various ligands, as well-established for the growth hormone receptor GHR. Using surface plasmon resonance we showed that the p.R96C point mutation completely abrogates SOCS2 binding affinity for the phosphopeptide of GHR. Additionally, the size, weight and milk production in p.R96C homozygote sheep, were significantly increased by 24%, 18%, and 4.4%, respectively, when compared to wild type sheep, supporting the view that the point mutation causes a loss of SOCS2 functional activity. Altogether these results provide strong evidence for a causal mutation controlling SCC in sheep and highlight the major role of SOCS2 as a tradeoff between the host's inflammatory response to mammary infections, and body growth and milk production, which are all mediated by the JAK/STAT signaling pathway.

  13. The analysis of longitudinal quality of life measures with informative drop-out : A pattern mixture approach

    NARCIS (Netherlands)

    Post, W.J.; Buijs, C.; Stolk, R.P.; de Vries, E.G.E.; le Cessie, S.

    The analysis of longitudinal health-related quality of life measures (HRQOL) can be seriously hampered due to informative drop-out. Random effects models assume Missing At Random and do not take into account informative drop-out. We therefore aim to correct the bias due to informative drop-out.

  14. Six Pillars of Effective Dropout Prevention and Recovery: An Assessment of Current State Policy and How to Improve It

    Science.gov (United States)

    Almeida, Cheryl; Steinberg, Adria; Santos, Janet; Le, Cecilia

    2010-01-01

    Solving America's dropout crisis requires immediate, drastic action. Intractable as the dropout problem may seem, recognition of its magnitude has created an environment ripe for action. Most notably, federal regulations adopted in 2008 require states to use more accurate ways of counting dropouts and holding districts and schools more accountable…

  15. School Dropouts or Pushouts? Overcoming Barriers for the Right to Education. CREATE Pathways to Access. Research Monograph No. 40

    Science.gov (United States)

    Reddy, Anugula N.; Sinha, Shantha

    2010-01-01

    Persistently high dropout rates are one of the biggest challenges to fulfilling the right to education in India. This paper attempts to assess the magnitude of the problem of dropout. The paper critically reviews the evidence on some of the commonly cited reasons for dropout, including poverty, limited to access to credit, child labour, and…

  16. Dropout is a problem in lifestyle intervention programs for overweight and obese infertile women : a systematic review

    NARCIS (Netherlands)

    Mutsaerts, M. A. Q.; Kuchenbecker, W. K. H.; Mol, B. W.; Land, J. A.; Hoek, A.

    What are the dropout rates in lifestyle intervention programs (LIPs) for overweight and obese infertile women and can intervention- or patient-related baseline factors associated with dropout be identified in these women? The median dropout rate was 24 in overweight and obese infertile women who

  17. Keeping Count of All and Losing Count of a Few: The Construction of the High School Dropout Rate

    Science.gov (United States)

    Henry, Shana Elizabeth

    2012-01-01

    The quality of the construction of the high school dropout rate is the policy issue investigated in this dissertation. This qualitative dissertation explores the constructs necessary to create a high school dropout rate and seeks to unearth complexities in the construction of the high school dropout rate. Every single year, approximately 1.2…

  18. [Differential aspects of treatment dropout risk in cocaine dependent patients with and without personality disorders].

    Science.gov (United States)

    Martínez-González, José Miguel; Albein-Urios, Natalia; Verdejo-García, Antonio; Lozano-Rojas, Oscar

    2014-01-01

    The aim of this study was to examine the link between psychosocial adjustment, impulsivity and comorbid Axis II psychopathology, and the risk of treatment dropout in cocaine dependent patients. The sample consisted of 95 cocaine dependent participants, 53.7% of whom had been diagnosed with Axis II personality disorders. We utilised a descriptive methodology, which allowed us to examine correlations between the different variables, group differences in these variables, and their ability to predict different dimensions associated with the risk of dropout. Results show that the risk of dropout during the first two months of treatment is not associated with the existence of comorbid personality disorders. With regard to the cognitive profiles of personality disorders, we show that the antisocial profile is associated with higher risk of dropout. The profile of patients at higher risk of treatment dropout is characterised by lower levels of perceived quality of life and elevated levels of impulsivity, especially the experience of strong impulses under positive affect. Therefore, the presence of psychological dimensions tightly associated with emotions, affects and subjective feelings are the more relevant to estimate the risk of treatment dropout in cocaine dependent patients. This study stresses the variables that need to be specifically addressed during early phases of cocaine addiction treatment, since they are associated with higher risk of treatment dropout.

  19. Medical school dropout--testing at admission versus selection by highest grades as predictors.

    Science.gov (United States)

    O'Neill, Lotte; Hartvigsen, Jan; Wallstedt, Birgitta; Korsholm, Lars; Eika, Berit

    2011-11-01

    Very few studies have reported on the effect of admission tests on medical school dropout. The main aim of this study was to evaluate the predictive validity of non-grade-based admission testing versus grade-based admission relative to subsequent dropout. This prospective cohort study followed six cohorts of medical students admitted to the medical school at the University of Southern Denmark during 2002-2007 (n=1544). Half of the students were admitted based on their prior achievement of highest grades (Strategy 1) and the other half took a composite non-grade-based admission test (Strategy 2). Educational as well as social predictor variables (doctor-parent, origin, parenthood, parents living together, parent on benefit, university-educated parents) were also examined. The outcome of interest was students' dropout status at 2 years after admission. Multivariate logistic regression analysis was used to model dropout. Strategy 2 (admission test) students had a lower relative risk for dropping out of medical school within 2 years of admission (odds ratio 0.56, 95% confidence interval 0.39-0.80). Only the admission strategy, the type of qualifying examination and the priority given to the programme on the national application forms contributed significantly to the dropout model. Social variables did not predict dropout and neither did Strategy 2 admission test scores. Selection by admission testing appeared to have an independent, protective effect on dropout in this setting. © Blackwell Publishing Ltd 2011.

  20. [A Cross-sectional Study of School dropout in adolescents: National Mental Health Survey Colombia 2015].

    Science.gov (United States)

    Gómez-Restrepo, Carlos; Padilla Muñoz, Andrea; Rincón, Carlos Javier

    2016-12-01

    School dropout in adolescents can have negative consequences, not only for the individual and the family, but also for the society. To identify the characteristics associated with the occurrence of this event might contribute to the planning of a prevention strategy. To evaluate the relationship between the individual and home characteristics and school dropout in adolescents from 12 to 17 years old in Colombia. A cross sectional study was conducted from information taken from the results obtained in the 2015 National Mental Health Survey. A study was made of the relationship between the individual and home characteristics and school dropout in adolescents from 12 to 17 years old RESULTS: A higher percentage of school dropouts was found in the older adolescents, females, and those who have children. Among the home characteristics, it was observed that those homes with more than two people, located in rural area, or that are classified as poor, have an increased percentage of school dropout adolescents. Strategies for which the main goal is to prevent school dropout should consider populations with higher prevalence of out-of-school adolescents (female, homes in rural area, or household poverty). Preventive actions of adolescent pregnancy might contribute to reduce the school dropout rate. Copyright © 2016 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  1. School factors related to dropout from primary and secondary education in Serbia: A qualitative research

    Directory of Open Access Journals (Sweden)

    Simić Nataša

    2017-01-01

    Full Text Available Dropping out of educational system is a serious individual, familial, educational and social problem. It is a complex process influenced by a large number of factors. Nevertheless, it is a phenomenon that takes place in school, and different school factors can serve as risk or protective factors. Dropout rates in Serbia are still high. One way to improve the educational system and ensure equal education for every child is to reduce dropout rates from primary and secondary education. As part of a larger study, the goal of this research was to investigate and identify key school factors related to dropout from primary and secondary schools in Serbia. The research was conducted in 8 primary and 13 secondary schools from 17 municipalities with high dropout rates. In order to hear voices from different actors in the educational system, qualitative research was conducted, involving interviews and focus groups with teachers, school principals, school psychologists, counsellors, pedagogical assistants, parents and students. Following the analysis, several school factors highly related to dropout were singled out. Low quality (individualisation of teaching, lack of learning and emotional support and lack of positive teacher-student relationships proved to have the greatest influence on student dropout. On the other hand, our results indicate that student and parent participation in school life is underused as a resource for dropout prevention. These factors are described and their impact in Serbian context explained. The results are discussed in the light of similar findings from previous research.

  2. An Imputation Model for Dropouts in Unemployment Data

    Directory of Open Access Journals (Sweden)

    Nilsson Petra

    2016-09-01

    Full Text Available Incomplete unemployment data is a fundamental problem when evaluating labour market policies in several countries. Many unemployment spells end for unknown reasons; in the Swedish Public Employment Service’s register as many as 20 percent. This leads to an ambiguity regarding destination states (employment, unemployment, retired, etc.. According to complete combined administrative data, the employment rate among dropouts was close to 50 for the years 1992 to 2006, but from 2007 the employment rate has dropped to 40 or less. This article explores an imputation approach. We investigate imputation models estimated both on survey data from 2005/2006 and on complete combined administrative data from 2005/2006 and 2011/2012. The models are evaluated in terms of their ability to make correct predictions. The models have relatively high predictive power.

  3. Control group design, contamination and drop-out in exercise oncology trials: a systematic review.

    Science.gov (United States)

    Steins Bisschop, Charlotte N; Courneya, Kerry S; Velthuis, Miranda J; Monninkhof, Evelyn M; Jones, Lee W; Friedenreich, Christine; van der Wall, Elsken; Peeters, Petra H M; May, Anne M

    2015-01-01

    Important considerations for exercise trials in cancer patients are contamination and differential drop-out among the control group members that might jeopardize the internal validity. This systematic review provides an overview of different control groups design characteristics of exercise-oncology trials and explores the association with contamination and drop-out rates. Randomized controlled exercise-oncology trials from two Cochrane reviews were included. Additionally, a computer-aided search using Medline (Pubmed), Embase and CINAHL was conducted after completion date of the Cochrane reviews. Eligible studies were classified according to three control group design characteristics: the exercise instruction given to controls before start of the study (exercise allowed or not); and the intervention the control group was offered during (any (e.g., education sessions or telephone contacts) or none) or after (any (e.g., cross-over or exercise instruction) or none) the intervention period. Contamination (yes or no) and excess drop-out rates (i.e., drop-out rate of the control group minus the drop-out rate exercise group) were described according to the three design characteristics of the control group and according to the combinations of these three characteristics; so we additionally made subgroups based on combinations of type and timing of instructions received. 40 exercise-oncology trials were included based on pre-specified eligibility criteria. The lowest contamination (7.1% of studies) and low drop-out rates (excess drop-out rate -4.7±9.2) were found in control groups offered an intervention after the intervention period. When control groups were offered an intervention both during and after the intervention period, contamination (0%) and excess drop-out rates (-10.0±12.8%) were even lower. Control groups receiving an intervention during and after the study intervention period have lower contamination and drop-out rates. The present findings can be

  4. Adolescent use of school-based health centers and high school dropout.

    Science.gov (United States)

    Kerns, Suzanne E U; Pullmann, Michael D; Walker, Sarah Cusworth; Lyon, Aaron R; Cosgrove, T J; Bruns, Eric J

    2011-07-01

    To determine the association between use of school-based health centers (SBHCs) and school dropout. Quasi-experimental longitudinal analysis of a retrospective student cohort, with SBHC use as the independent variable. We statistically controlled for dropout risk and used propensity score regression adjustment to control for several factors associated with SBHC use. Integrated database from an urban public school district (academic outcomes) and department of public health (SBHC use). District-enrolled students in their first semester of ninth grade in 2005 (N = 3334), followed up through their anticipated on-time graduation semester of 12th grade in 2009. Students were divided into 4 groups: never used (47%); low use (23%); moderate use (20%); and high users (10%). Time to nongraduation (described as dropout). Low to moderate SBHC use (0.125-2.5 visits per semester) was associated with a 33% reduction in dropout compared with non-SBHC users. The high-use group (>2.5 visits per semester) did not have dropout rates that differed from nonusers. For SBHC users who did drop out, dropout occurred approximately 1 semester later than nonusers. Exploratory analyses revealed that the association between SBHC use and prevention of dropout was greatest for higher-risk students. This study found an association between low to moderate SBHC use and reductions in dropout for high school students in an urban school district, especially for students at higher risk for dropout. This study supports the theory that benefits of SBHCs extend beyond managing physical and mental health needs to include academic outcomes.

  5. Predicting Dropout from Intensive Outpatient Cognitive Behavioural Therapy for Binge Eating Disorder Using Pre-treatment Characteristics: A Naturalistic Study.

    Science.gov (United States)

    Vroling, Maartje S; Wiersma, Femke E; Lammers, Mirjam W; Noorthoorn, Eric O

    2016-11-01

    Dropout rates in binge eating disorder (BED) treatment are high (17-30%), and predictors of dropout are unknown. Participants were 376 patients following an intensive outpatient cognitive behavioural therapy programme for BED, 82 of whom (21.8%) dropped out of treatment. An exploratory logistic regression was performed using eating disorder variables, general psychopathology, personality and demographics to identify predictors of dropout. Binge eating pathology, preoccupations with eating, shape and weight, social adjustment, agreeableness, and social embedding appeared to be significant predictors of dropout. Also, education showed an association to dropout. This is one of the first studies investigating pre-treatment predictors for dropout in BED treatment. The total explained variance of the prediction model was low, yet the model correctly classified 80.6% of cases, which is comparable to other dropout studies in eating disorders. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

  6. Addition by Subtraction: The Relation Between Dropout Rates and School-Level Academic Achievement

    Science.gov (United States)

    GLENNIE, ELIZABETH; BONNEAU, KARA; VANDELLEN, MICHELLE; DODGE, KENNETH A.

    2013-01-01

    Background/Context Efforts to improve student achievement should increase graduation rates. However, work investigating the effects of student-level accountability has consistently demonstrated that increases in the standards for high school graduation are correlated with increases in dropout rates. The most favored explanation for this finding is that high-stakes testing policies that mandate grade repetition and high school exit exams may be the tipping point for students who are already struggling academically. These extra demands may, in fact, push students out of school. Purpose/Objective/Focus This article examines two hypotheses regarding the relation between school-level accountability and dropout rates. The first posits that improvements in school performance lead to improved success for everyone. If school-level accountability systems improve a school for all students, then the proportion of students performing at grade level increases, and the dropout rate decreases. The second hypothesis posits that schools facing pressure to improve their overall accountability score may pursue this increase at the cost of other student outcomes, including dropout rate. Research Design Our approach focuses on the dynamic relation between school-level academic achievement and dropout rates over time—that is, between one year’s achievement and the subsequent year’s dropout rate, and vice versa. This article employs longitudinal data of records on all students in North Carolina public schools over an 8-year period. Analyses employ fixed-effects models clustering schools and districts within years and controls each year for school size, percentage of students who were free/reduced-price lunch eligible, percentage of students who are ethnic minorities, and locale. Findings/Results This study finds partial evidence that improvements in school-level academic performance will lead to improvements (i.e., decreases) in school-level dropout rates. Schools with improved

  7. Addition by Subtraction: The Relation Between Dropout Rates and School-Level Academic Achievement.

    Science.gov (United States)

    Glennie, Elizabeth; Bonneau, Kara; Vandellen, Michelle; Dodge, Kenneth A

    2012-01-01

    Efforts to improve student achievement should increase graduation rates. However, work investigating the effects of student-level accountability has consistently demonstrated that increases in the standards for high school graduation are correlated with increases in dropout rates. The most favored explanation for this finding is that high-stakes testing policies that mandate grade repetition and high school exit exams may be the tipping point for students who are already struggling academically. These extra demands may, in fact, push students out of school. This article examines two hypotheses regarding the relation between school-level accountability and dropout rates. The first posits that improvements in school performance lead to improved success for everyone. If school-level accountability systems improve a school for all students, then the proportion of students performing at grade level increases, and the dropout rate decreases. The second hypothesis posits that schools facing pressure to improve their overall accountability score may pursue this increase at the cost of other student outcomes, including dropout rate. Our approach focuses on the dynamic relation between school-level academic achievement and dropout rates over time-that is, between one year's achievement and the subsequent year's dropout rate, and vice versa. This article employs longitudinal data of records on all students in North Carolina public schools over an 8-year period. Analyses employ fixed-effects models clustering schools and districts within years and controls each year for school size, percentage of students who were free/reduced-price lunch eligible, percentage of students who are ethnic minorities, and locale. This study finds partial evidence that improvements in school-level academic performance will lead to improvements (i.e., decreases) in school-level dropout rates. Schools with improved performance saw decreased dropout rates following these successes. However, we find

  8. Dynamic Output Feedback Control for Nonlinear Networked Control Systems with Random Packet Dropout and Random Delay

    Directory of Open Access Journals (Sweden)

    Shuiqing Yu

    2013-01-01

    Full Text Available This paper investigates the dynamic output feedback control for nonlinear networked control systems with both random packet dropout and random delay. Random packet dropout and random delay are modeled as two independent random variables. An observer-based dynamic output feedback controller is designed based upon the Lyapunov theory. The quantitative relationship of the dropout rate, transition probability matrix, and nonlinear level is derived by solving a set of linear matrix inequalities. Finally, an example is presented to illustrate the effectiveness of the proposed method.

  9. Genome-Wide Linkage Scan for Prostate Cancer Susceptibility in Finland: Evidence for a Novel Locus on 2q37.3 and confirmation of signal on 17q21-q22

    Science.gov (United States)

    Cropp, Cheryl D.; Simpson, Claire L; Wahlfors, Tiina; Ha, Nati; George, Asha; Jones, MaryPat S.; Harper, Ursula; Ponciano-Jackson, Damaris; Green, Tiffany A.; Tammela, Teuvo L. J.; Bailey-Wilson, Joan; Schleutker, Johanna

    2011-01-01

    Genome-wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes. Linkage studies performed in different ethnic backgrounds and populations have been somewhat disparate, resulting in multiple, often irreproducible signals because of genetic heterogeneity and high sporadic background of the disease. Our first genome-wide linkage study and subsequent fine-mapping study of Finnish hereditary prostate cancer (HPC) families gave evidence of linkage to one region. Here, we conducted subsequent scans with microsatellites and SNPs in a total of 69 Finnish HPC families. GENEHUNTER-PLUS was used for parametric and non-parametric analyses. Our microsatellite genome-wide linkage study provided evidence of linkage to 17q12-q23, with a heterogeneity LOD (HLOD) score of 3.14 in a total of 54 of the 69 families. Genome-wide SNP analysis of 59 of the 69 families gave a highest HLOD score of 3.40 at 2q37.3 under a dominant high penetrance model. Analyzing all 69 families by combining microsatellite and SNP maps also yielded HLOD scores of > 3.3 in two regions (2q37.3 and 17q12-q21.3). These significant linkage peaks on chromosome 2 and 17 confirm previous linkage evidence of a locus on 17q from other populations and provide a basis for continued research into genetic factors involved in PRCA. Fine-mapping analysis of these regions is ongoing and candidate genes at linked loci are currently under analysis. PMID:21207418

  10. Genome-wide linkage scan for prostate cancer susceptibility in Finland: evidence for a novel locus on 2q37.3 and confirmation of signal on 17q21-q22.

    Science.gov (United States)

    Cropp, Cheryl D; Simpson, Claire L; Wahlfors, Tiina; Ha, Nati; George, Asha; Jones, MaryPat S; Harper, Ursula; Ponciano-Jackson, Damaris; Green, Tiffany A; Tammela, Teuvo L J; Bailey-Wilson, Joan; Schleutker, Johanna

    2011-11-15

    Genome-wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes. Linkage studies performed in different ethnic backgrounds and populations have been somewhat disparate, resulting in multiple, often irreproducible signals because of genetic heterogeneity and high sporadic background of the disease. Our first genome-wide linkage study and subsequent fine-mapping study of Finnish hereditary prostate cancer (HPC) families gave evidence of linkage to one region. Here, we conducted subsequent scans with microsatellites and SNPs in a total of 69 Finnish HPC families. GENEHUNTER-PLUS was used for parametric and nonparametric analyses. Our microsatellite genome-wide linkage study provided evidence of linkage to 17q12-q23, with a heterogeneity LOD (HLOD) score of 3.14 in a total of 54 of the 69 families. Genome-wide SNP analysis of 59 of the 69 families gave a highest HLOD score of 3.40 at 2q37.3 under a dominant high penetrance model. Analyzing all 69 families by combining microsatellite and SNP maps also yielded HLOD scores of > 3.3 in two regions (2q37.3 and 17q12-q21.3). These significant linkage peaks on chromosome 2 and 17 confirm previous linkage evidence of a locus on 17q from other populations and provide a basis for continued research into genetic factors involved in PRCA. Fine-mapping analysis of these regions is ongoing and candidate genes at linked loci are currently under analysis. Copyright © 2011 UICC.

  11. Prediction of Student Dropout in E-Learning Program Through the Use of Machine Learning Method

    Directory of Open Access Journals (Sweden)

    Mingjie Tan

    2015-02-01

    Full Text Available The high rate of dropout is a serious problem in E-learning program. Thus it has received extensive concern from the education administrators and researchers. Predicting the potential dropout students is a workable solution to prevent dropout. Based on the analysis of related literature, this study selected student’s personal characteristic and academic performance as input attributions. Prediction models were developed using Artificial Neural Network (ANN, Decision Tree (DT and Bayesian Networks (BNs. A large sample of 62375 students was utilized in the procedures of model training and testing. The results of each model were presented in confusion matrix, and analyzed by calculating the rates of accuracy, precision, recall, and F-measure. The results suggested all of the three machine learning methods were effective in student dropout prediction, and DT presented a better performance. Finally, some suggestions were made for considerable future research.

  12. ENHANCED PREDICTION OF STUDENT DROPOUTS USING FUZZY INFERENCE SYSTEM AND LOGISTIC REGRESSION

    Directory of Open Access Journals (Sweden)

    A. Saranya

    2016-01-01

    Full Text Available Predicting college and school dropouts is a major problem in educational system and has complicated challenge due to data imbalance and multi dimensionality, which can affect the low performance of students. In this paper, we have collected different database from various colleges, among these 500 best real attributes are identified in order to identify the factor that affecting dropout students using neural based classification algorithm and different mining technique are implemented for data processing. We also propose a Dropout Prediction Algorithm (DPA using fuzzy logic and Logistic Regression based inference system because the weighted average will improve the performance of whole system. We are experimented our proposed work with all other classification systems and documented as the best outcomes. The aggregated data is given to the decision trees for better dropout prediction. The accuracy of overall system 98.6% it shows the proposed work depicts efficient prediction.

  13. The new dropout challenge: bridging gaps among students, parents, and teachers.

    Science.gov (United States)

    Bridgeland, John M

    2010-01-01

    Interview and survey data reveal significant disconnects among the insights and perspectives of dropouts, parents, teachers, and administrators on the causes and solutions to the dropout challenge. Many educators, for example, do not see boredom as a factor for most dropouts, while young people who drop out see it as the central cause. The author argues that if these disconnects are not more fully understood and bridged, they will continue to set back efforts to keep more students in school and on track to graduate ready for postsecondary education. Models for how communities can engage these constituencies in productive dialogue and transformative action are included in reports and in Grad Nation, a guidebook that helps communities tackle their dropout crises.

  14. No-shows, drop-outs and completers in psychotherapeutic treatment

    DEFF Research Database (Denmark)

    Fenger, Morten Munthe; Mortensen, Erik Lykke; Poulsen, Stig Bernt

    2011-01-01

    A primary challenge in mental health services is a high rate of non-attendance (i.e. no-show and drop-out) for patients referred to treatment for psychiatric disorders.......A primary challenge in mental health services is a high rate of non-attendance (i.e. no-show and drop-out) for patients referred to treatment for psychiatric disorders....

  15. Reducing dropout among traumatized alcohol patients in detoxification treatment : A pilot intervention study

    OpenAIRE

    Odenwald, Michael; Semrau, Peter

    2012-01-01

    Dropout rates from detoxification treatment are high. We tested whether high trauma event load was related to a higher dropout from alcohol detoxification. Furthermore, we studied the feasibility and effects of a short psychoeducational tool to increase retention among traumatized alcohol in-patients. Retention and treatment length were compared between treatment as usual (TAU) and standard therapy plus a psychoeducational group intervention on alcohol drinking related to stress and trauma (P...

  16. Patterns, Consequences, and Possible Causes of Dropout in Upper Secondary Education in Mexico

    Directory of Open Access Journals (Sweden)

    Raja Bentaouet Kattan

    2015-01-01

    Full Text Available The present study provides a detailed analysis of upper secondary education dropout patterns in Mexico, exploring its consequences and possible causes. To perform the analysis we combine different databases and statistical methods ranging from the use of surveys with information on specific individuals to data aggregated at the municipal and state level. The main value added is the simultaneous analysis of the influence of individual-family, community, and macroaggregate factors, on school dropout in the country.

  17. Bayesian informative dropout model for longitudinal binary data with random effects using conditional and joint modeling approaches.

    Science.gov (United States)

    Chan, Jennifer S K

    2016-05-01

    Dropouts are common in longitudinal study. If the dropout probability depends on the missing observations at or after dropout, this type of dropout is called informative (or nonignorable) dropout (ID). Failure to accommodate such dropout mechanism into the model will bias the parameter estimates. We propose a conditional autoregressive model for longitudinal binary data with an ID model such that the probabilities of positive outcomes as well as the drop-out indicator in each occasion are logit linear in some covariates and outcomes. This model adopting a marginal model for outcomes and a conditional model for dropouts is called a selection model. To allow for the heterogeneity and clustering effects, the outcome model is extended to incorporate mixture and random effects. Lastly, the model is further extended to a novel model that models the outcome and dropout jointly such that their dependency is formulated through an odds ratio function. Parameters are estimated by a Bayesian approach implemented using the user-friendly Bayesian software WinBUGS. A methadone clinic dataset is analyzed to illustrate the proposed models. Result shows that the treatment time effect is still significant but weaker after allowing for an ID process in the data. Finally the effect of drop-out on parameter estimates is evaluated through simulation studies. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. PROXIMAL AND DISTAL FACTORS ASSOCIATED WITH DROPOUT VERSUS MAINTAINED PARTICIPATION IN ORGANIZED SPORT

    Directory of Open Access Journals (Sweden)

    Julie C.S. Boiché

    2009-03-01

    Full Text Available The purpose of this study was to investigate a large number of determinants of sport dropout among French adolescents, in order to reveal proximal and distal factors of dropout. 261 current and 106 dropout athletes (M = 14.6 participated to the study. The data were collected by a questionnaire assessing demographic information, athletes' perceptions on their experience, their parents, teammates and coach. t-tests revealed that current and former athletes were distinct on numerous variables. A discriminant function analysis showed three proximal predictors of sport dropout (perceived value of the activity, satisfaction, parents' investment. Subsequent regression analyses showed that perceived value was positively predicted by perceived competence, the value of the activity for teammates, coach's investment, and negatively by conflicts of interest and goal conflict with teammates; satisfaction was positively predicted by the coach's mastery climate, but negatively predicted by conflicts of interest and goal conflict with teammates and with the coach; parents investment was negatively predicted by the goal conflicts with them. This study permitted to discriminate between proximal and more distal psychological antecedents of the dropout behaviour. It brings information relative to the possible targets of interventions aiming at preventing dropout from organized sport

  19. Predictors of drop-out in an Internet study of men who have sex with men.

    Science.gov (United States)

    Jain, Amit; Ross, Michael W

    2008-10-01

    Researchers have suggested the rising use of Internet to look for sexual partners is an important contributor to the resurgence in the incidence of sexually transmitted diseases (STDs) and HIV among men who have sex with men (MSM). Web-based samples of this population reflect good geographical diversity for research, but a high drop-out rate creates a significant potential for bias, misrepresentation of population, and misinterpretation of data. This study aims to describe the demographics of an Internet sample of MSM and the differences between the completers and drop-outs. We analyzed data obtained from a cross-sectional study using an online self-administered questionnaire for males, 18 years or older, who were current U.S. residents, and who had sex with men. Of 850 eligible participants, 404 (47.5%) were labeled as drop-outs. The completers and drop-outs differed significantly in age, education, country of birth, health insurance, time spent on Internet, location of computer access, types of sites visited, profile information, last homosexual experience, methods used to determine safety of partners, and type of sexual activities on real meets. Almost half of the participants dropped out before completion. Although the two groups did not differ in many of the items, high drop-out rates are a threat to the validity of such data. Drop-out constitutes a significant bias in Internet sexuality research and must be considered while interpreting the results of such studies.

  20. Therapist effects on dropout from a college counseling center practice research network.

    Science.gov (United States)

    Xiao, Henry; Castonguay, Louis G; Janis, Rebecca A; Youn, Soo Jeong; Hayes, Jeffrey A; Locke, Benjamin D

    2017-07-01

    Dropout has been a pervasive and costly problem in psychotherapy, particularly for college counseling centers. The present study examined potential predictors of dropout using a large data set (N = 10,147 clients, 481 therapists) that was gathered through a college counseling center practice research network as a replication and extension of recent findings regarding therapist effects on dropout. The final model resulted in a dropout rate of 15.9% and a therapist effect of 9.51% on dropout variance. Therapist demographic variables were investigated, though none were found to be significant. Variables found to be predictive of increased likelihood of dropping out included higher levels of general presenting concerns, alcohol-related distress, and current financial stress. Ultimately, this study showed that therapists may play an important role in the likelihood of client dropout, and that additional research should be conducted to identify additional predictors, particularly at the therapist and center level. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Baseline Motivation Type as a Predictor of Dropout in a Healthy Eating Text Messaging Program.

    Science.gov (United States)

    Coa, Kisha; Patrick, Heather

    2016-09-29

    Growing evidence suggests that text messaging programs are effective in facilitating health behavior change. However, high dropout rates limit the potential effectiveness of these programs. This paper describes patterns of early dropout in the HealthyYou text (HYTxt) program, with a focus on the impact of baseline motivation quality on dropout, as characterized by Self-Determination Theory (SDT). This analysis included 193 users of HYTxt, a diet and physical activity text messaging intervention developed by the US National Cancer Institute. Descriptive statistics were computed, and logistic regression models were run to examine the association between baseline motivation type and early program dropout. Overall, 43.0% (83/193) of users dropped out of the program; of these, 65.1% (54/83; 28.0% of all users) did so within the first 2 weeks. Users with higher autonomous motivation had significantly lower odds of dropping out within the first 2 weeks. A one unit increase in autonomous motivation was associated with lower odds (odds ratio 0.44, 95% CI 0.24-0.81) of early dropout, which persisted after adjusting for level of controlled motivation. Applying SDT-based strategies to enhance autonomous motivation might reduce early dropout rates, which can improve program exposure and effectiveness.

  2. Relationship of dropout and psychopathology in a high school sample in Mexico.

    Science.gov (United States)

    Chalita, Pablo J; Palacios, Lino; Cortes, Jose F; Landeros-Weisenberger, Angeli; Panza, Kaitlyn E; Bloch, Michael H

    2012-01-01

    School dropout has significant consequences for both individuals and societies. Only 21% of adults in Mexico achieve the equivalent of a high school education. We examined the relationship between school dropout and self-reported psychiatric symptoms in a middle school in a suburb of Mexico City. We used binomial logistic regression to examine the odds ratio (OR) of school dropout associated with students' self-reported psychopathology. Two-hundred thirty-seven students participated in the study. Psychosis [OR = 8.0 (95% confidence interval, CI: 1.7-37.2)], depression [OR = 4.7 (95% CI: 2.2-9.7)], tic disorders [OR = 3.7 (95% CI: 1.4-9.5)], ADHD [OR = 3.2 (95% CI: 1.5-6.4)], and social phobia [OR = 2.6 (95% CI: 1.2-5.8)] were associated with increased risk of school dropout after controlling for age and gender as covariates. Our study suggested that students' self-reported psychopathology is associated with increased school dropout in Mexico. ADHD and depression may be particularly useful childhood psychiatric disorders to target with public health interventions because they explain the greatest amount of the variance in school dropout of child psychiatric disorders.

  3. Local Access to Family Planning Services and Female High School Dropout Rates.

    Science.gov (United States)

    Hicks-Courant, Katherine; Schwartz, Aaron L

    2016-04-01

    To assess whether geographic access to family planning services is associated with a reduced female high school dropout rate. We conducted a retrospective cross-sectional study. We merged the location of Planned Parenthood and Title X clinics with microdata from the 2012-2013 American Community Surveys. The association between female high school dropout rates and local clinic access was assessed using nearest-neighbor matching estimation. Models included various covariates to account for sociodemographic differences across communities and male high school dropout rates to account for unmeasured community characteristics affecting educational outcomes. Our sample included 284,910 16- to 22-year-old females. The presence of a Planned Parenthood clinic was associated with a decrease (4.08% compared with 4.83%; relative risk ratio 0.84, Pschool dropout rates. This association was consistent across several model specifications. The presence of a Title X clinic was associated with a decrease (4.79% compared with 5.07%; relative risk ratio 0.94, P=.03) in female high school dropout rates, an association that did not remain significant across model specifications. Local access to Planned Parenthood is associated with lower high school dropout rates in young women.

  4. [Prediction and Prevention of Dropouts in Vocational Retraining].

    Science.gov (United States)

    Baumann, R

    2016-06-01

    Principal objective: To verify if a psychological intervention targeting individuals with high resignation tendency prevents dropouts in vocational retraining. For individuals with high resignation tendency a high risk of dropping out was assumed under regular conditions. Data was collected at 2 adult education institutes. At the beginning of vocational training the occupational inventory Work-related Behaviour and Experience Patterns (AVEM) was used. The questionnaire allows to classify 4 types of coping behaviour. G: healthy-ambitious, S: unambitious, A: excessively ambitious, B: resigned. Using a quasi-experimental design, the effect of resilience building was verified by comparing a treatment group with a control group. Control group was offered the usual treatment of the education institute. The treatment group was additionally offered two individual meetings and a work-related group treatment focussing on coping behaviour. Given a very high resignation tendency in both groups, dropping out of rehabilitation was less frequent in the treatment group. Other individuals tended to drop out more frequently, but this is not statistically significant. The study shows that work-related resilience building helps to minimize risk of dropping out of vocational rehabilitation in the case of extremely resigned coping behaviour. © Georg Thieme Verlag KG Stuttgart · New York.

  5. Bariatric surgery insurance requirements independently predict surgery dropout.

    Science.gov (United States)

    Love, Kaitlin M; Mehaffey, J Hunter; Safavian, Dana; Schirmer, Bruce; Malin, Steven K; Hallowell, Peter T; Kirby, Jennifer L

    2017-05-01

    Many insurance companies have considerable prebariatric surgery requirements despite a lack of evidence for improved clinical outcomes. The hypothesis of this study is that insurance-specific requirements will be associated with a decreased progression to surgery and increased delay in time to surgery. Retrospective data collection was performed for patients undergoing bariatric surgery evaluation from 2010-2015. Patients who underwent surgery (SGY; n = 827; mean body mass index [BMI] 49.1) were compared with those who did not (no-SGY; n = 648; mean BMI: 49.4). Univariate and multivariate analysis were performed to identify specific co-morbidity and insurance specific predictors of surgical dropout and time to surgery. A total of 1475 patients using 12 major insurance payors were included. Univariate analysis found insurance requirements associated with surgical drop out included longer median diet duration (no-SGY = 6 mo; SGY = 3 mo; Prequirement (odds ratio [OR] .88, Prequirements were associated with lack of patient progression to surgery in this study. In addition, delays in surgery were associated with preoperative weight gain. Although prospective and multicenter studies are needed, these findings have major policy implications suggesting insurance requirements may need to be reconsidered to improve medical care. Copyright © 2017 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  6. Hospital admissions and school dropout: a retrospective cohort study of the 'selection hypothesis'.

    Science.gov (United States)

    van Heesch, Mirjam M J; Bosma, Hans; Traag, Tanja; Otten, Ferdy

    2012-08-01

    School dropout is an important predictor of poor health and of high relevance for public health (in accord with the 'causation hypothesis'). Rather than examining how dropout affects health, we set out to examine how poor health might affect school dropout (in accord with the 'selection hypothesis'). Hospital admissions are potentially indicative of more serious disease and might be expected to result in learning backlogs. Longitudinal data of the Dutch Secondary Education Pupil Cohort 1993 (VOCL'93) and the National Medical Registration (LMR) were combined. The study population consisted of 16,239 pupils who were followed from first grade at secondary school until they left fulltime education. Pupils were monitored regarding both their educational careers and their hospital admissions. Nine percent had a hospital admission and 10% became a school dropout. Hospital admissions were only predictive of later school dropout for pupils starting in the highest type of secondary education (pre-university education) [OR 1.54 (95% CI 1.05-2.26)], not for pupils with lower educational levels. Pre-university pupils who had been hospitalized for more than 9 days [OR 2.34 (95% CI 1.08-5.09)] or who were hospitalized more than three times [OR 4.20 (95% CI 1.75-10.04)] had particularly heightened odds of school dropout. Our findings further support the 'selection hypothesis' and confirm the relevance of dropout for public health. Public health workers and educational professionals should probably aim at intensified monitoring of children who have been hospitalized and simultaneously aim at improving accessibility to (higher quality) education in the hospital.

  7. Enhanced low-template DNA analysis conditions and investigation of allele dropout patterns.

    Science.gov (United States)

    Hedell, Ronny; Dufva, Charlotte; Ansell, Ricky; Mostad, Petter; Hedman, Johannes

    2015-01-01

    Forensic DNA analysis applying PCR enables profiling of minute biological samples. Enhanced analysis conditions can be applied to further push the limit of detection, coming with the risk of visualising artefacts and allele imbalances. We have evaluated the consecutive increase of PCR cycles from 30 to 35 to investigate the limitations of low-template (LT) DNA analysis, applying the short tandem repeat (STR) analysis kit PowerPlex ESX 16. Mock crime scene DNA extracts of four different quantities (from around 8-84 pg) were tested. All PCR products were analysed using 5, 10 and 20 capillary electrophoresis (CE) injection seconds. Bayesian models describing allele dropout patterns, allele peak heights and heterozygote balance were developed to assess the overall improvements in EPG quality with altered PCR/CE settings. The models were also used to evaluate the impact of amplicon length, STR marker and fluorescent label on the risk for allele dropout. The allele dropout probability decreased for each PCR cycle increment from 30 to 33 PCR cycles. Irrespective of DNA amount, the dropout probability was not affected by further increasing the number of PCR cycles. For the 42 and 84 pg samples, mainly complete DNA profiles were generated applying 32 PCR cycles. For the 8 and 17 pg samples, the allele dropouts decreased from 100% using 30 cycles to about 75% and 20%, respectively. The results for 33, 34 and 35 PCR cycles indicated that heterozygote balance and stutter ratio were mainly affected by DNA amount, and not directly by PCR cycle number and CE injection settings. We found 32 and 33 PCR cycles with 10 CE injection seconds to be optimal, as 34 and 35 PCR cycles did not improve allele detection and also included CE saturation problems. We find allele dropout probability differences between several STR markers. Markers labelled with the fluorescent dyes CXR-ET (red in electropherogram) and TMR-ET (shown as black) generally have higher dropout risks compared with those

  8. Socioeconomic differences in school dropout among young adults: the role of social relations.

    Science.gov (United States)

    Winding, Trine Nøhr; Andersen, Johan Hviid

    2015-10-15

    School dropout in adolescence is an important social determinant of health inequality in a lifetime perspective. It is commonly accepted that parental background factors are associated with later dropout, but to what extent social relations mediate this association is not yet fully understood. To investigate the effect of social relations on the association between parental socioeconomic position and school dropout in the Danish youth cohort Vestliv. This prospective study used data from questionnaires in 2004 and 2007 and register data in 2004 and 2010. The study population consisted of 3,054 persons born in 1989. Information on dropout was dichotomised into those who had completed a secondary education/were still attending one and those who had dropped out/had never attended a secondary education. Logistic regression analyses were used to investigate associations between parental socioeconomic position and dropout at age 21, taking into account effects of social relations at age 15 and 18. A large proportion of young people were having problems with social relations at age 15 and 18. In general, social relations were strongly related to not completing a secondary education, especially among girls. For instance, 18-year-old girls finding family conflicts difficult to handle had a 2.6-fold increased risk of not completing a secondary education. Young people from low socioeconomic position families had approximately a 3-fold higher risk of not completing a secondary education compared to young people from high position families, and the estimates did not change greatly after adjustment for social relations with family or friends. Poor relations with teachers and classmates at age 18 explained a substantial part of the association between income and dropout among both girls and boys. The study confirmed a social gradient in completion of secondary education. Despite the fact that poor social relations at age 15 and 18 were related to dropout at age 21, social

  9. Modeling the Magnetopause Shadowing Loss during the October 2012 Dropout Event

    Science.gov (United States)

    Tu, Weichao; Cunningham, Gregory

    2017-04-01

    The relativistic electron flux in Earth's outer radiation belt are observed to drop by orders of magnitude on timescales of a few hours, which is called radiation belt dropouts. Where do the electrons go during the dropouts? This is one of the most important outstanding questions in radiation belt studies. Radiation belt electrons can be lost either by precipitation into the atmosphere or by transport across the magnetopause into interplanetary space. The latter mechanism is called magnetopause shadowing, usually combined with outward radial diffusion of electrons due to the sharp radial gradient it creates. In order to quantify the relative contribution of these two mechanisms to radiation belt dropout, we performed an event study on the October 2012 dropout event observed by Van Allen Probes. First, the precipitating MeV electrons observed by multiple NOAA POES satellites at low altitude did not show evidence of enhanced precipitation during the dropout, which suggested that precipitation was not the dominant loss mechanism for the event. Then, in order to simulate the magnetopause shadowing loss and outward radial diffusion during the dropout, we applied a radial diffusion model with electron lifetimes on the order of electron drift periods outside the last closed drift shell. In addition, realistic and event-specific inputs of radial diffusion coefficients (DLL) and last closed drift shell (LCDS) were implemented in the model. Specifically, we used the new DLL developed by Cunningham [JGR 2016] which were estimated in realistic TS04 [Tsyganenko and Sitnov, JGR 2005] storm time magnetic field model and included physical K (2nd adiabatic invariant) or pitch angle dependence. Event-specific LCDS traced in TS04 model with realistic K dependence was also implemented. Our simulation results showed that these event-specific inputs are critical to explain the electron dropout during the event. The new DLL greatly improved the model performance at low L* regions (L*<3

  10. Stereotype confirmation concerns predict dropout from cognitive behavioral therapy for social anxiety disorder.

    Science.gov (United States)

    Johnson, Suzanne; Price, Matthew; Mehta, Natasha; Anderson, Page L

    2014-08-19

    There are high attrition rates observed in efficacy studies for social anxiety disorder, and research has not identified consistent nor theoretically meaningful predictors of dropout. Pre-treatment symptom severity and demographic factors, such as age and gender, are sometimes predictive of dropout. The current study examines a theoretically meaningful predictor of attrition based on experiences associated with social group membership rather than differences between social group categories--fear of confirming stereotypes. This is a secondary data analysis of a randomized controlled trial comparing two cognitive behavioral treatments for social anxiety disorder: virtual reality exposure therapy and exposure group therapy. Participants (N = 74) with a primary diagnosis of social anxiety disorder who were eligible to participate in the parent study and who self-identified as either "African American" (n = 31) or "Caucasian" (n = 43) completed standardized self-report measures of stereotype confirmation concerns (SCC) and social anxiety symptoms as part of a pre-treatment assessment battery. Hierarchical logistic regression showed that greater stereotype confirmation concerns were associated with higher dropout from therapy--race, age, gender, and pre-treatment symptom severity were not. Group treatment also was associated with higher dropout. These findings urge further research on theoretically meaningful predictors of attrition and highlight the importance of addressing cultural variables, such as the experience of stereotype confirmation concerns, during treatment of social anxiety to minimize dropout from therapy.

  11. Modeling and Output Feedback Control of Networked Control Systems with Both Time Delays; and Packet Dropouts

    Directory of Open Access Journals (Sweden)

    Li Qiu

    2013-01-01

    Full Text Available This paper is concerned with the problem of modeling and output feedback controller design for a class of discrete-time networked control systems (NCSs with time delays and packet dropouts. A Markovian jumping method is proposed to deal with random time delays and packet dropouts. Different from the previous studies on the issue, the characteristics of networked communication delays and packet dropouts can be truly reflected by the unified model; namely, both sensor-to-controller (S-C and controller-to-actuator (C-A time delays, and packet dropouts are modeled and their history behavior is described by multiple Markov chains. The resulting closed-loop system is described by a new Markovian jump linear system (MJLS with Markov delays model. Based on Lyapunov stability theory and linear matrix inequality (LMI method, sufficient conditions of the stochastic stability and output feedback controller design method for NCSs with random time delays and packet dropouts are presented. A numerical example is given to illustrate the effectiveness of the proposed method.

  12. Relationship between Self-Reported Psychopathology and Future Dropout in a Mexican School

    Directory of Open Access Journals (Sweden)

    Pablo J Chalita

    2012-03-01

    Full Text Available School dropout has significant consequences for both individuals and societies. Only 21% of adults in Mexico achieve the equivalent of a high school education. We examined the relationship between school dropout and self-reported psychiatric symptoms in a middle school in a suburb of Mexico City. We used binomial logistic regression to examine the odd ratio of school dropout associated with student’s self-reported psychopathology. Two-hundred thirty seven students participated in the study. Psychosis (Odds Ratio (OR=8.0 (95% Confidence Interval (CI: 1.7-37.2, depression (OR=4.7 (95% CI: 2.2-9.7, tic disorders (OR=3.7 (95%CI: 1.4-9.5, ADHD (OR=3.2 (95%CI:1.5-6.4, and social phobia (OR=2.6 (95%CI: 1.2-5.8 were associated with increased risk of school dropout after controlling for age and gender as covariates. Our study suggested that students’ self-reported psychopathology is associated with increased school dropout in Mexico.

  13. Gender, Success, and Drop-Out during a Resistance Exercise Program in Community Dwelling Old Adults

    Directory of Open Access Journals (Sweden)

    O. G. Geirsdottir

    2017-01-01

    Full Text Available Background. Resistance exercise training can be effective against sarcopenia. We identified predictors of drop-out and compared physical outcomes between men and women after such training. Methods. Subjects (N=236, 73.7±5.7 years participated in a 12-week resistance exercise program. Outcome variables were measured at baseline and endpoint. Results. Drop-out was 11.9% and not significantly different between genders. Drop-outs were significantly older and had poorer strength and physical function in comparison to completers. Anthropometrics, QoL, and cognitive function were not related to drop-out. According to multivariate analysis, gait speed and physical activity were the strongest predictors of drop-out. After the training, gains in lean mass or appendicular muscle were significantly higher in men than women; however relative gains in appendicular muscle as well as absolute improvements in strength and function were similar in men and women, respectively. Conclusions. Participants who drop out are older, have poorer physical function, and are less physically active. Old women do not drop out more frequently than men and show meaningful improvements in relevant outcomes similar to men after such a training program. The trial is registered at the US National Library of Medicine (NCT01074879.

  14. Drop-out during a randomized trial with adolescents with intellectual disability was associated with participant burden, while drop-out at study exit was associated with carer and household characteristics.

    Science.gov (United States)

    Ware, Robert S; McPherson, Lyn; Lennox, Nicholas G

    2017-12-01

    People with intellectual disability are difficult to retain in longitudinal studies. Research on determinants of study retention for individual-carer dyads, and their reasons for drop-out, are limited. To investigate characteristics associated with drop-out, and to investigate whether characteristics varied by stage of drop-out. Data are from an Australian randomized trial with adolescents with intellectual disability living in the community. Characteristics of both the adolescent and their nominated carer were collected at baseline. Carers were sent an exit questionnaire approximately two years after enrolment. Baseline information was available for 566 adolescents: 72(13.0%) withdrew during the study, and 96(17.3%) didn't return exit questionnaires. Characteristics associated with drop-out during the study were being in the intervention group, the carer being younger, and the carer not being one of the adolescent's parents. Characteristics associated with withdrawal at exit were carer having lower education and carer having lower socioeconomic status. No adolescent characteristic was associated with drop-out. Characteristics of drop-outs weren't related to the adolescent and differed according to timing. Drop-out during the study was associated with study burden, whereas characteristics of drop-outs at exit interview were associated with lower social position. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. What predicts outcome, response, and drop-out in CBT of depressive adults? a naturalistic study.

    Science.gov (United States)

    Schindler, Amrei; Hiller, Wolfgang; Witthöft, Michael

    2013-05-01

    The efficacy of CBT for unipolar depressive disorders is well established, yet not all patients improve or tolerate treatment. To identify factors associated with symptomatic outcome, response, and drop-out in depressive patients under naturalistic CBT. 193 patients with major depression or dysthymia were tested. Sociodemographic and clinical variables were entered as predictors in hierarchical regression analyses. A higher degree of pretreatment depression, early improvement, and completion of therapy were identified as predictors for symptomatic change and response. Drop-out was predicted by concurrent personality disorder, less positive outcome expectancies, and by failure to improve early in treatment. Our results highlight the importance of early response to predict improvement in routine CBT. Attempts to refine the quality of treatment programs should focus on avoiding premature termination (drop-out) and consider motivational factors in more depth. Routinely administered standardized assessments would enhance symptom monitoring and help to identify persons at risk of not improving under therapy.

  16. Medical school dropout - testing at admission versus selection by highest grades as predictors

    DEFF Research Database (Denmark)

    O'Neill, Lotte Dyhrberg; Hartvigsen, Jan; Wallstedt, Birgitta

    2011-01-01

    Medical Education 2011: 45: 1111-1120 Context  Very few studies have reported on the effect of admission tests on medical school dropout. The main aim of this study was to evaluate the predictive validity of non-grade-based admission testing versus grade-based admission relative to subsequent...... dropout. Methods  This prospective cohort study followed six cohorts of medical students admitted to the medical school at the University of Southern Denmark during 2002-2007 (n = 1544). Half of the students were admitted based on their prior achievement of highest grades (Strategy 1) and the other half...... years after admission. Multivariate logistic regression analysis was used to model dropout. Results  Strategy 2 (admission test) students had a lower relative risk for dropping out of medical school within 2 years of admission (odds ratio 0.56, 95% confidence interval 0.39-0.80). Only the admission...

  17. Towards peer education prevention of school dropout: An exploratory analysis of an action-research study

    Directory of Open Access Journals (Sweden)

    Colucci Gabriella

    2017-01-01

    Full Text Available This paper presents the exploratory analysis of an action-research into dropout prevention in an Italian secondary school. By taking into account the representations of teachers, students and parents, different activities of peer education have been implemented during the school year in a city of Sardinia in order to promote school success. The study is based on a mixed-methods design, including focus groups with teachers, students and parents, as well as classroom observations. The action-research consists of different interventions: firstly, the participants’ representations of school dropout have been collected; then, a specific program of peer education has been proposed through activities of role-playing, simulations, brainstorming, and improvement of life skills (during training meetings with the participants. Thereafter, the action-research has been qualitatively analysed, with the findings indicating possible directions of re-creating school practices that could have potential benefits in preventing dropout.

  18. Dynamic Average Consensus and Consensusability of General Linear Multiagent Systems with Random Packet Dropout

    Directory of Open Access Journals (Sweden)

    Wen-Min Zhou

    2013-01-01

    Full Text Available This paper is concerned with the consensus problem of general linear discrete-time multiagent systems (MASs with random packet dropout that happens during information exchange between agents. The packet dropout phenomenon is characterized as being a Bernoulli random process. A distributed consensus protocol with weighted graph is proposed to address the packet dropout phenomenon. Through introducing a new disagreement vector, a new framework is established to solve the consensus problem. Based on the control theory, the perturbation argument, and the matrix theory, the necessary and sufficient condition for MASs to reach mean-square consensus is derived in terms of stability of an array of low-dimensional matrices. Moreover, mean-square consensusable conditions with regard to network topology and agent dynamic structure are also provided. Finally, the effectiveness of the theoretical results is demonstrated through an illustrative example.

  19. Susceptibility to malignant hyperthermia

    NARCIS (Netherlands)

    Snoeck, Marcus Matheus Johannes

    2004-01-01

    In this thesis the author studied the diagnostic procedures for susceptibility to malignant hyperthermia (MH), with special emphasis upon refining the biological diagnostic test and improving protocols and guidelines for investigation of MH susceptibility. MH is a pharmacogenetic disease of skeletal

  20. Simulations of Lateral Transport and Dropout Structure of Energetic Particles from Impulsive Solar Flares

    Science.gov (United States)

    Matthaeus, W. H.; Ruffolo, D. J.; Tooprakai, P.; Seripienlert, A.; Chuychai, P.

    2016-12-01

    We simulate trajectories of energetic particles from impulsive solar flares for 2D+slab models of magnetic turbulence in spherical geometry to study dropout features, i.e., sharp, repeated changes in the particle density, and the particles' lateral transport. Among random-phase realizations of 2D turbulence, a spherical harmonic expansion can generate homogeneous turbulence over a sphere, but a 2D fast Fourier transform (FFT) locally mapped onto the lateral coordinates in the region of interest is much faster computationally, and we show that the results are qualitatively similar. We then use the 2D FFT field as input to a 2D MHD simulation, which dynamically generates realistic features of turbulence such as coherent structures. The magnetic field lines and particles spread non-diffusively (ballistically) to a patchy distribution reaching up to 25° from the injection longitude and latitude at r 1 AU. This dropout pattern in field line trajectories has sharper features in the case of the more realistic 2D MHD model, in better qualitative agreement with observations. The initial dropout pattern in particle trajectories is relatively insensitive to particle energy, though the energy affects the pattern's evolution with time. We make predictions for future observations of solar particles near the Sun (e.g., at 0.25 AU), for which we expect a sharp pulse of outgoing particles along the dropout pattern, followed by backscattering that first remains close to the dropout pattern and later exhibits cross-field transport to a distribution that is more diffusive, yet mostly contained within the dropout pattern found at greater distances. Partially supported by the Thailand Research Fund (Grants BRG5880009 and RTA5980003), the U.S. NSF (AGS-1063439), NASA (NNX14AI63G & NNX15AB88G), and the Solar Probe Plus/ISIS project.

  1. Did the 18 Drinking Age Promote High School Dropout? Implications for Current Policy.

    Science.gov (United States)

    Plunk, Andrew D; Agrawal, Arpana; Tate, William F; Cavazos-Rehg, Patricia; Bierut, Laura J; Grucza, Richard A

    2015-09-01

    Disagreement exists over whether permissive minimum legal drinking age (MLDA) laws affected underage adolescents (e.g., those age 17 years with the MLDA of 18). We used MLDA changes during the 1970s and 1980s as a natural experiment to investigate how underage exposure to permissive MLDA affected high school dropout. MLDA exposure was added to two data sets: (a) the 5% public use microdata samples of the 1990 and 2000 censuses (n = 3,671,075), and (b) a combined data set based on the 1991-1992 National Longitudinal Alcohol Epidemiological Survey (NLAES) and the 2001-2002 National Epidemiological Survey on Alcohol and Related Conditions (NESARC; n = 16,331). We used logistic regression to model different thresholds of MLDA on high school dropout. We also estimated models conditioned on demographic variables and familial risk of developing alcohol problems. Only the MLDA of 18 predicted high school dropout. Exposure was associated with 4% and 13% higher odds of high school dropout for the census and NLAES/NESARC samples, respectively. We noted greater impact on women (5%-18%), Blacks (5%-19%), and Hispanics (6%). Self-report of parental alcohol problems was associated with 40% higher odds, which equals a 4.14-point increase in dropout rate for that population. The MLDA of 18 likely had a large impact on high school dropout rates, suggesting that the presence of legal-aged peers in a high school setting increased access to alcohol for younger students. Our results also suggest that policy can promote less dangerous drinking behavior even when familial risk of alcohol use disorders is high.

  2. Quantifying the Precipitation Loss of Radiation Belt Electrons During a Rapid Dropout Event

    Science.gov (United States)

    Pham, K. H.; Tu, W.; Xiang, Z.

    2017-10-01

    Relativistic electron flux in the radiation belt can drop by orders of magnitude within the timespan of hours. In this study, we used the drift-diffusion model that includes azimuthal drift and pitch angle diffusion of electrons to simulate low-altitude electron distribution observed by POES/MetOp satellites for rapid radiation belt electron dropout event occurring on 1 May 2013. The event shows fast dropout of MeV energy electrons at L > 4 over a few hours, observed by the Van Allen Probes mission. By simulating the electron distributions observed by multiple POES satellites, we resolve the precipitation loss with both high spatial and temporal resolutions and a range of energies. We estimate the pitch angle diffusion coefficients as a function of energy, pitch angle, and L-shell and calculate corresponding electron lifetimes during the event. The simulation results show fast electron precipitation loss at L > 4 during the electron dropout, with estimated electron lifetimes on the order of half an hour for MeV energies. The electron loss rate shows strong energy dependence with faster loss at higher energies, which suggest that this dropout event is dominated by quick and localized scattering process that prefers higher energy electrons. The improved temporal and spatial resolutions of electron precipitation rates provided by multiple low-altitude observations can resolve fast-varying electron loss during rapid electron dropouts (over a few hours), which occur too fast for a single low-altitude satellite. The capability of estimating the fast-varying electron lifetimes during rapid dropout events is an important step in improving radiation belt model accuracy.

  3. Did the 18 Drinking Age Promote High School Dropout? Implications for Current Policy

    Science.gov (United States)

    Plunk, Andrew D.; Agrawal, Arpana; Tate, William F.; Cavazos-Rehg, Patricia; Bierut, Laura J.; Grucza, Richard A.

    2015-01-01

    Objective: Disagreement exists over whether permissive minimum legal drinking age (MLDA) laws affected underage adolescents (e.g., those age 17 years with the MLDA of 18). We used MLDA changes during the 1970s and 1980s as a natural experiment to investigate how underage exposure to permissive MLDA affected high school dropout. Method: MLDA exposure was added to two data sets: (a) the 5% public use microdata samples of the 1990 and 2000 censuses (n = 3,671,075), and (b) a combined data set based on the 1991–1992 National Longitudinal Alcohol Epidemiological Survey (NLAES) and the 2001–2002 National Epidemiological Survey on Alcohol and Related Conditions (NESARC; n = 16,331). We used logistic regression to model different thresholds of MLDA on high school dropout. We also estimated models conditioned on demographic variables and familial risk of developing alcohol problems. Results: Only the MLDA of 18 predicted high school dropout. Exposure was associated with 4% and 13% higher odds of high school dropout for the census and NLAES/NESARC samples, respectively. We noted greater impact on women (5%–18%), Blacks (5%–19%), and Hispanics (6%). Self-report of parental alcohol problems was associated with 40% higher odds, which equals a 4.14-point increase in dropout rate for that population. Conclusions: The MLDA of 18 likely had a large impact on high school dropout rates, suggesting that the presence of legal-aged peers in a high school setting increased access to alcohol for younger students. Our results also suggest that policy can promote less dangerous drinking behavior even when familial risk of alcohol use disorders is high. PMID:26402348

  4. A Systematic Review and Meta-Analysis Estimating the Expected Dropout Rates in Randomized Controlled Trials on Yoga Interventions

    Directory of Open Access Journals (Sweden)

    Holger Cramer

    2016-01-01

    Full Text Available A reasonable estimation of expected dropout rates is vital for adequate sample size calculations in randomized controlled trials (RCTs. Underestimating expected dropouts rates increases the risk of false negative results while overestimating rates results in overly large sample sizes, raising both ethical and economic issues. To estimate expected dropout rates in RCTs on yoga interventions, MEDLINE/PubMed, Scopus, IndMED, and the Cochrane Library were searched through February 2014; a total of 168 RCTs were meta-analyzed. Overall dropout rate was 11.42% (95% confidence interval [CI] = 10.11%, 12.73% in the yoga groups; rates were comparable in usual care and psychological control groups and were slightly higher in exercise control groups (rate = 14.53%; 95% CI = 11.56%, 17.50%; odds ratio = 0.82; 95% CI = 0.68, 0.98; p=0.03. For RCTs with durations above 12 weeks, dropout rates in yoga groups increased to 15.23% (95% CI = 11.79%, 18.68%. The upper border of 95% CIs for dropout rates commonly was below 20% regardless of study origin, health condition, gender, age groups, and intervention characteristics; however, it exceeded 40% for studies on HIV patients or heterogeneous age groups. In conclusion, dropout rates can be expected to be less than 15 to 20% for most RCTs on yoga interventions. Yet dropout rates beyond 40% are possible depending on the participants’ sociodemographic and health condition.

  5. The Influence of Computer Technology Learning Program on Attitudes toward Computers and Self-Esteem among Arab Dropout Youth.

    Science.gov (United States)

    Romi, Shlomo; Zoabi, Houssien

    2003-01-01

    Describes a study that examined the attitudes of Arab dropout youth in Israel toward the use of computer technology and the influence of this use on their self-esteem. Results supported the assumptions that exposure to computer technology would change the attitudes of dropout adolescents toward computers to positive ones. (Contains 43 references.)…

  6. Predicting dropout from intensive outpatient cognitive behavioural therapy for binge eating disorder using pre-treatment characteristics: A naturalistic study

    NARCIS (Netherlands)

    Vroling, M.S.; Wiersma, F.E.; Lammers, M.W.; Noorthoorn, E.O.

    2016-01-01

    Background: Dropout rates in binge eating disorder (BED) treatment are high (17-30%), and predictors of dropout are unknown. Method: Participants were 376 patients following an intensive outpatient cognitive behavioural therapy programme for BED, 82 of whom (21.8%) dropped out of treatment. An

  7. Are Barbie and Ken too cool for school? A case-control study on the relation between gender and dropout

    NARCIS (Netherlands)

    Theunissen, M.J.; de Man, I.; Verdonk, P.; Bosma, H.; Feron, F.

    2015-01-01

    Background: As school dropout is an important public health problem that needs to be addressed, we set out to examine whether and how, beyond the well-known effects of sex, gender beliefs and self-reported masculinity and femininity are related to school dropout. Methods: The study used a

  8. A Multidimensional Model of School Dropout from an 8-Year Longitudinal Study in a General High School Population

    Science.gov (United States)

    Fortin, Laurier; Marcotte, Diane; Diallo, Thierno; Potvin, Pierre; Royer, Egide

    2013-01-01

    This study tests an empirical multidimensional model of school dropout, using data collected in the first year of an 8-year longitudinal study, with first year high school students aged 12-13 years. Structural equation modeling analyses show that five personal, family, and school latent factors together contribute to school dropout identified at…

  9. A Competing Risks Survival Analysis of High School Dropout and Graduation: A Two-Stage Model Specification Approach

    Science.gov (United States)

    Yang, Fan

    2017-01-01

    There has been a wealth of research conducted on the high school dropouts spanning several decades. It is estimated that compared with those who complete high school, the average high school dropout costs the economy approximately $250,000 more over his or her lifetime in terms of lower tax contributions, higher reliance on Medicaid and Medicare,…

  10. Academic Fatalism: Applying Durkheim's Fatalistic Suicide Typology to Student Drop-Out and the Climate of Higher Education

    Science.gov (United States)

    Godor, Brian P.

    2017-01-01

    Student drop-out remains a critical issue facing educational professionals. For higher education, the vast research in the past 40 years has been influenced by the work of Tinto and his model of student persistence. In this model are several elements that have proven to sharpen the focus of student drop-out research such as the concept of…

  11. SPECTROSCOPIC CONFIRMATION OF THREE z-DROPOUT GALAXIES AT z = 6.844-7.213: DEMOGRAPHICS OF Ly{alpha} EMISSION IN z {approx} 7 GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Ono, Yoshiaki; Shimasaku, Kazuhiro; Nakajima, Kimihiko, E-mail: ono@astron.s.u-tokyo.ac.jp [Department of Astronomy, Graduate School of Science, University of Tokyo, Tokyo 113-0033 (Japan); Ouchi, Masami [Institute for Cosmic Ray Research, University of Tokyo, Kashiwa 277-8582 (Japan); Mobasher, Bahram; Nayyeri, Hooshang [Department of Physics and Astronomy, University of California, Riverside, CA 92521 (United States); Dickinson, Mark; Kartaltepe, Jeyhan S. [National Optical Astronomical Observatories, Tucson, AZ 85719 (United States); Penner, Kyle [Department of Astronomy, University of Arizona, Tucson, AZ 85721 (United States); Weiner, Benjamin J. [Steward Observatory, University of Arizona, Tucson, AZ 85721 (United States); Stern, Daniel [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Kashikawa, Nobunari [Optical and Infrared Astronomy Division, National Astronomical Observatory of Japan, Tokyo 181-8588 (Japan); Spinrad, Hyron [Department of Astronomy, University of California, Berkeley, CA 94720 (United States)

    2012-01-10

    We present the results of our ultra-deep Keck/DEIMOS spectroscopy of z-dropout galaxies in the Subaru Deep Field and Great Observatories Origins Deep Survey's northern field. For 3 out of 11 objects, we detect an emission line at {approx}1 {mu}m with a signal-to-noise ratio of {approx}10. The lines show asymmetric profiles with high weighted skewness values, consistent with being Ly{alpha}, yielding redshifts of z = 7.213, 6.965, and 6.844. Specifically, we confirm the z = 7.213 object in two independent DEIMOS runs with different spectroscopic configurations. The z = 6.965 object is a known Ly{alpha} emitter, IOK-1, for which our improved spectrum at a higher resolution yields a robust skewness measurement. The three z-dropouts have Ly{alpha} fluxes of 3 Multiplication-Sign 10{sup -17} erg s{sup -1} cm{sup -2} and rest-frame equivalent widths EW{sup Ly{alpha}}{sub 0} = 33-43 A. Based on the largest spectroscopic sample of 43 z-dropouts, which is the combination of our and previous data, we find that the fraction of Ly{alpha}-emitting galaxies (EW{sup Ly{alpha}}{sub 0} > 25 A) is low at z {approx} 7; 17% {+-} 10% and 24% {+-} 12% for bright (M{sub UV} {approx_equal} -21) and faint (M{sub UV} {approx_equal} -19.5) galaxies, respectively. The fractions of Ly{alpha}-emitting galaxies drop from z {approx} 6 to 7 and the amplitude of the drop is larger for faint galaxies than for bright galaxies. These two pieces of evidence would indicate that the neutral hydrogen fraction of the intergalactic medium increases from z {approx} 6 to 7 and that the reionization proceeds from high- to low-density environments, as suggested by an inside-out reionization model.

  12. Reducing dropout of contact lens wear with Biotrue multipurpose solution

    Directory of Open Access Journals (Sweden)

    Rah MJ

    2014-01-01

    week. Keywords: multipurpose solution, contact lens, dropout

  13. Impact of dropout of female volunteer community health workers: An exploration in Dhaka urban slums

    Directory of Open Access Journals (Sweden)

    Alam Khurshid

    2012-08-01

    Full Text Available Abstract Background The model of volunteer community health workers (CHWs is a common approach to serving the poor communities in developing countries. BRAC, a large NGO in Bangladesh, is a pioneer in this area, has been using female CHWs as core workers in its community-based health programs since 1977. After 25 years of implementing of the CHW model in rural areas, BRAC has begun using female CHWs in urban slums through a community-based maternal health intervention. However, BRAC experiences high dropout rates among CHWs suggesting a need to better understand the impact of their dropout which would help to reduce dropout and increase program sustainability. The main objective of the study was to estimate impact of dropout of volunteer CHWs from both BRAC and community perspectives. Also, we estimated cost of possible strategies to reduce dropout and compared whether these costs were more or less than the costs borne by BRAC and the community. Methods We used the ‘ingredient approach’ to estimate the cost of recruiting and training of CHWs and the so-called ‘friction cost approach’ to estimate the cost of replacement of CHWs after adapting. Finally, we estimated forgone services in the community due to CHW dropout applying the concept of the friction period. Results In 2009, average cost per regular CHW was US$ 59.28 which was US$ 60.04 for an ad-hoc CHW if a CHW participated a three-week basic training, a one-day refresher training, one incentive day and worked for a month in the community after recruitment. One month absence of a CHW with standard performance in the community meant substantial forgone health services like health education, antenatal visits, deliveries, referrals of complicated cases, and distribution of drugs and health commodities. However, with an additional investment of US$ 121 yearly per CHW BRAC could save another US$ 60 invested an ad-hoc CHW plus forgone services in the community. Conclusion Although CHWs

  14. Why Wait? Early Determinants of School Dropout in Preventive Pediatric Primary Care.

    Directory of Open Access Journals (Sweden)

    Marie-José Theunissen

    Full Text Available To answer the question of what bio-psychosocial determinants in infancy, early and middle childhood, and adolescence predict school drop-out in young adulthood, we approached the complex process towards school dropout as a multidimensional, life-course phenomenon. The aim is to find signs of heightened risks of school dropout as early as possible which will eventually help public health workers in reducing these risks.In a case-control design, we used data from both the Preventive Pediatric Primary Care (PPPC files (that contain information from birth onwards and additional questionnaires filled out by 529 youngsters, aged 18-23 years, and living in the South-east of the Netherlands. We first conducted univariate logistic regression analyses with school-dropout as the dependent variable. Backward and forward stepwise analyses with the significant variables were done with variables pertaining to the 0 to 4 year period. Remaining significant variables were forced into the next model and subsequently variables pertaining to respectively the 4 to 8, 8 to 12 and 12 to 16 year period were introduced in a stepwise analysis. All analyses were cross-validated in an exploratory and confirmatory random half of the sample.One parent families and families with a non-Western background less often attended the health examinations of the PPPC and such less attendance was related to school dropout. The birth of a sibling (OR 0.63, 95% CI 0.43-0.93 in infancy and self-efficacy (OR 0.53, 95% CI 0.38-0.74 in adolescence decreased the odds of school dropout; externalizing behavior (OR 2.81, 95% CI 1.53-5.14 in middle childhood and (sickness absence (OR 5.62, 95% CI 2.18-14.52 in adolescence increased the risks.To prevent school dropout, PPPC professionals should not wait until imminent dropout, but should identify and tackle risk factors as early as possible and actively approach youngsters who withdraw from public health care.

  15. Deep Retinal Layer Microvasculature Dropout Detected by the Optical Coherence Tomography Angiography in Glaucoma.

    Science.gov (United States)

    Suh, Min Hee; Zangwill, Linda M; Manalastas, Patricia Isabel C; Belghith, Akram; Yarmohammadi, Adeleh; Medeiros, Felipe A; Diniz-Filho, Alberto; Saunders, Luke J; Weinreb, Robert N

    2016-12-01

    To investigate factors associated with dropout of the parapapillary deep retinal layer microvasculature assessed by optical coherence tomography angiography (OCTA) in glaucomatous eyes. Cross-sectional study. Seventy-one eyes from 71 primary open-angle glaucoma (POAG) patients with β-zone parapapillary atrophy (βPPA) enrolled in the Diagnostic Innovations in Glaucoma Study. Parapapillary deep-layer microvasculature dropout was defined as a complete loss of the microvasculature located within the deep retinal layer of the βPPA from OCTA-derived optic nerve head vessel density maps by standardized qualitative assessment. Circumpapillary vessel density (cpVD) within the retinal nerve fiber layer (RNFL) also was calculated using OCTA. Choroidal thickness and presence of focal lamina cribrosa (LC) defects were determined using swept-source optical coherence tomography. Presence of parapapillary deep-layer microvasculature dropout. Parameters including age, systolic and diastolic blood pressure, axial length, intraocular pressure, disc hemorrhage, cpVD, visual field (VF) mean deviation (MD), focal LC defects βPPA area, and choroidal thickness were analyzed. Parapapillary deep-layer microvasculature dropout was detected in 37 POAG eyes (52.1%). Eyes with microvasculature dropout had a higher prevalence of LC defects (70.3% vs. 32.4%), lower cpVD (52.7% vs. 58.8%), worse VF MD (-9.06 dB vs. -3.83 dB), thinner total choroidal thickness (126.5 μm vs. 169.1 μm), longer axial length (24.7 mm vs. 24.0 mm), larger βPPA (1.2 mm2 vs. 0.76 mm2), and lower diastolic blood pressure (74.7 mmHg vs. 81.7 mmHg) than those without dropout (P microvasculature dropout in glaucomatous eyes. Longitudinal studies are required to elucidate the temporal relationship between parapapillary deep-layer microvasculature dropout and systemic and ocular factors. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  16. An Explorative Analysis of Children’s Dropouts from Rural Schools of Pakistan

    OpenAIRE

    Muhammad Mehar AKRAM

    2011-01-01

    The purpose of this paper is to present an explorative analysis about the causes of children’s high proportion of drop-outs from rural schools of Pakistan. For this purpose, simple random sampling technique was used by taking a sample size of 120 respondents from six villages of the rural areas of district Jhang, Pakistan in 2010. The major objectives of the said research were to investigate the socio-economic hurdles of the drop-outs of children from schools, to find out the attitude of pare...

  17. Ability, Parental Valuation of Education and the High School Dropout Decision

    DEFF Research Database (Denmark)

    Foley, Kelly; Gallipoli, Giovanni; Green, David

    that teenage boys with two parents who are themselves high school dropouts have a 16% chance of dropping out, compared to a dropout rate of less than 1% for boys whose parents both have a university degree. We examine the channels through which this socio-economic gradient arises using an extended version......We use a large, rich Canadian micro-level dataset to examine the channels through which family socio-economic status and unobservable characteristics a ect children's decisions to drop out of high school. First, we document the strength of observable socio-economic factors: our data suggest...

  18. Why Wait? Early Determinants of School Dropout in Preventive Pediatric Primary Care.

    Science.gov (United States)

    Theunissen, Marie-José; Bosma, Hans; Verdonk, Petra; Feron, Frans

    2015-01-01

    To answer the question of what bio-psychosocial determinants in infancy, early and middle childhood, and adolescence predict school drop-out in young adulthood, we approached the complex process towards school dropout as a multidimensional, life-course phenomenon. The aim is to find signs of heightened risks of school dropout as early as possible which will eventually help public health workers in reducing these risks. In a case-control design, we used data from both the Preventive Pediatric Primary Care (PPPC) files (that contain information from birth onwards) and additional questionnaires filled out by 529 youngsters, aged 18-23 years, and living in the South-east of the Netherlands. We first conducted univariate logistic regression analyses with school-dropout as the dependent variable. Backward and forward stepwise analyses with the significant variables were done with variables pertaining to the 0 to 4 year period. Remaining significant variables were forced into the next model and subsequently variables pertaining to respectively the 4 to 8, 8 to 12 and 12 to 16 year period were introduced in a stepwise analysis. All analyses were cross-validated in an exploratory and confirmatory random half of the sample. One parent families and families with a non-Western background less often attended the health examinations of the PPPC and such less attendance was related to school dropout. The birth of a sibling (OR 0.63, 95% CI 0.43-0.93) in infancy and self-efficacy (OR 0.53, 95% CI 0.38-0.74) in adolescence decreased the odds of school dropout; externalizing behavior (OR 2.81, 95% CI 1.53-5.14) in middle childhood and (sickness) absence (OR 5.62, 95% CI 2.18-14.52) in adolescence increased the risks. To prevent school dropout, PPPC professionals should not wait until imminent dropout, but should identify and tackle risk factors as early as possible and actively approach youngsters who withdraw from public health care.

  19. Estimating the probability of allelic drop-out of STR alleles in forensic genetics

    DEFF Research Database (Denmark)

    Tvedebrink, Torben; Eriksen, Poul Svante; Mogensen, Helle Smidt

    2009-01-01

    In crime cases with available DNA evidence, the amount of DNA is often sparse due to the setting of the crime. In such cases, allelic drop-out of one or more true alleles in STR typing is possible. We present a statistical model for estimating the per locus and overall probability of allelic drop......-out using the results of all STR loci in the case sample as reference. The methodology of logistic regression is appropriate for this analysis, and we demonstrate how to incorporate this in a forensic genetic framework....

  20. Medical school dropout - testing at admission versus selection by highest grades as predictors

    OpenAIRE

    O?Neill, Lotte Dyhrberg; Hartvigsen, Jan; Wallstedt, Birgitta; Korsholm, Lars; Eika, Berit

    2011-01-01

    Medical Education 2011: 45: 1111-1120 Context  Very few studies have reported on the effect of admission tests on medical school dropout. The main aim of this study was to evaluate the predictive validity of non-grade-based admission testing versus grade-based admission relative to subsequent dropout. Methods  This prospective cohort study followed six cohorts of medical students admitted to the medical school at the University of Southern Denmark during 2002-2007 (n = 1544). Half of the stud...

  1. Segmentation of intracranial arterial calcification with deeply supervised residual dropout networks

    DEFF Research Database (Denmark)

    Bortsova, Gerda; van Tulder, Gijs; Dubost, Florian

    2017-01-01

    convolutional neural network that we extend with two regularization techniques. Firstly, we use deep supervision to encourage discriminative features in the hidden layers. Secondly, we augment the network with skip connections, as in the recently developed ResNet, and dropout layers, inserted in a way that skip...... connections circumvent them. We investigate the effect of skip connections and dropout. In addition, we propose a simple problem-specific modification of the network objective function that restricts the focus to the most important image regions and simplifies the optimization. We train and validate our model...

  2. An exploration of students’ own explanations about dropout in vocational education in a danish context

    DEFF Research Database (Denmark)

    Tanggaard, Lene

    2013-01-01

    is considered in terms of two very different, but intersecting broad explanations voiced by students themselves: (1) as something created in educational institutions in various situations, such as when teachers spend more time and resources on the more affluent, quick-witted and clever students or when......The present paper addresses the phenomenon of student dropout from vocational education in Denmark. It does so by addressing the need to critically discuss the term ‘drop-out’ taking the perspective of students’ own reflections on the topic. The empirical findings indicate that dropout...... interviews with students in eight different basic vocational educational courses in Denmark....

  3. Explaining the Rise in Danish Vocational Education System Dropouts: The Effect of a Youth Unemployment Program

    DEFF Research Database (Denmark)

    Munk, Martin D.; Park, Do-Yeun

    This project focuses on the impact of Denmark’s Youth Unemployment Program(YUP) enacted in late 1990s on the rise in VET dropout rates. The Youth Unemployment Program targeted unemployed, low-educated youth to strengthen the employment possibilities and to motivate for them to undertake...... an education. If the Youth Unemployment Program incentivized less capable/ambitious students to enter vocational education, it would increase the dropout rates via selection. This project investigates whether the program had an effect on the population characteristics of incoming VET students and the resulting...

  4. Allelic Dropout in the ENG Gene, Affecting the Results of Genetic Testing in Hereditary Hemorrhagic Telangiectasia

    DEFF Research Database (Denmark)

    Tørring, Pernille M; Kjeldsen, A.D.; Ousager, L.B.

    2012-01-01

    Background: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal-dominant vascular disorder with three disease-causing genes identified to date: ENG, ACVRL1, and SMAD4. We report an HHT patient with allelic dropout that on routine sequence analysis for a known mutation in the family (c.817......-3T>G in ENG) initially seemed to be homozygous for the mutation. Aim: To explore the possibility of allelic dropout causing a false result in this patient. Methods: Mutation analysis of additional family members was performed and haplotype analysis carried out. New primers were designed to reveal...

  5. I want to quit education: a longitudinal study of stress and optimism as predictors of school dropout intention.

    Science.gov (United States)

    Eicher, Véronique; Staerklé, Christian; Clémence, Alain

    2014-10-01

    Prior research on school dropout has often focused on stable person- and institution-level variables. In this research, we investigate longitudinally perceived stress and optimism as predictors of dropout intentions over a period of four years, and distinguish between stable and temporary predictors of dropout intentions. Findings based on a nationally representative sample of 16-20 year-olds in Switzerland (N = 4312) show that both average levels of stress and optimism as well as annually varying levels of stress and optimism affect dropout intentions. Additionally, results show that optimism buffers the negative impact of annually varying stress (i.e., years with more stress than usual), but not of stable levels of stress (i.e., stress over four years). The implications of the results are discussed according to a dynamic and preventive approach of school dropout. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  6. Direct and Indirect Pathways From Adverse Childhood Experiences to High School Dropout Among High-Risk Adolescents.

    Science.gov (United States)

    Morrow, Anne S; Villodas, Miguel T

    2017-07-24

    Adverse childhood experiences (ACEs) are associated with an increased risk for school dropout. This study examined pathways from childhood adversity to school dropout through academic, behavioral, emotional, and social pathways. Data were collected prospectively from 728 adolescents and their caregivers who participated in the Longitudinal Studies of Child Abuse and Neglect and from child protective services records. Path analyses revealed a direct association between ACEs and dropout, as well as indirect effects through poor reading achievement and elevated externalizing problems. ACEs were associated with elevated internalizing problems, which were negatively associated with dropout. However, ACEs were not associated with peer influences. Implications of the identified mechanisms in the ACEs and school dropout association for future preventive interventions are discussed. © 2017 The Authors. Journal of Research on Adolescence © 2017 Society for Research on Adolescence.

  7. The early identification of risk factors on the pathway to school dropout in the SIODO study: a sequential mixed-methods study

    NARCIS (Netherlands)

    Theunissen, J.A.M.; Griensven, I.A.N.v.; Verdonk, P.; Feron, F.; Bosma, H.

    2012-01-01

    Background: School dropout is a persisting problem with major socioeconomic consequences. Although poor health probably contributes to pathways leading to school dropout and health is likely negatively affected by dropout, these issues are relatively absent on the public health agenda. This

  8. Factors associated with non-participation and drop-out in a lifestyle intervention for workers with an elevated risk of cardiovascular disease

    NARCIS (Netherlands)

    Groeneveld, Iris F.; Proper, Karin I.; van der Beek, Allard J.; Hildebrandt, Vincent H.; van Mechelen, Willem

    2009-01-01

    Non-response and drop-out are problems that are commonly encountered in health promotion trials. Understanding the health-related characteristics of non-participants and drop-outs and the reasons for non-participation and drop-out may be beneficial for future intervention trials. Male construction

  9. Factors associated with non-participation and drop-out in a lifestyle intervention for workers with an elevated risk of cardiovascular disease

    NARCIS (Netherlands)

    Groeneveld, I.F.; Proper, K.I.; Beek, A.J. van der; Hildebrandt, V.H.; Mechelen, W. van

    2009-01-01

    Background: Non-response and drop-out are problems that are commonly encountered in health promotion trials. Understanding the health-related characteristics of non-participants and drop-outs and the reasons for non-participation and drop-out may be beneficial for future intervention trials.

  10. Adolescent health and high school dropout: a prospective cohort study of 9000 Norwegian adolescents (the Young-HUNT).

    Science.gov (United States)

    De Ridder, Karin A A; Pape, Kristine; Johnsen, Roar; Holmen, Turid Lingaas; Westin, Steinar; Bjørngaard, Johan Håkon

    2013-01-01

    High school dropout is of major concern in the western world. Our aims were to estimate the risk of school dropout in adolescents following chronic somatic disease, somatic symptoms, psychological distress, concentration difficulties, insomnia or overweight and to assess to which extent the family contributes to the association between health and school dropout. A population of 8950 school-attending adolescents (13-21 years) rated their health in the Young-HUNT 1 Study (90% response rate) in 1995-1997. High school dropout or completion, was defined with the Norwegian National Education Database in the calendar year the participant turned 24 years old. Parental socioeconomic status was defined by using linkages to the National Education Database, the National Insurance Administration and the HUNT2 Survey. We used logistic regression to estimate odds ratios and risk differences of high school dropout, both in the whole population and among siblings within families differentially exposed to health problems. All explored health dimensions were strongly associated with high school dropout. In models adjusted for parental socioeconomic status, the risk differences of school dropout according to health exposures varied between 3.6% (95% CI 1.7 to 5.5) for having ≥ 1 somatic disease versus none and 11.7% (6.3 to 17.0) for being obese versus normal weight. The results from the analyses comparing differentially exposed siblings, confirmed these results with the exception of weaker associations for somatic diseases and psychological distress. School dropout was strongly clustered within families (family level conditional intraclass correlation 0.42). Adolescent health problems are markers for high school dropout, independent of parental socioeconomic status. Although school dropout it strongly related to family-level factors, also siblings with poor health have reduced opportunity to complete high school compared to healthy siblings. Public health policy should focus on

  11. Adolescent health and high school dropout: a prospective cohort study of 9000 Norwegian adolescents (the Young-HUNT.

    Directory of Open Access Journals (Sweden)

    Karin A A De Ridder

    Full Text Available BACKGROUND: High school dropout is of major concern in the western world. Our aims were to estimate the risk of school dropout in adolescents following chronic somatic disease, somatic symptoms, psychological distress, concentration difficulties, insomnia or overweight and to assess to which extent the family contributes to the association between health and school dropout. METHODS: A population of 8950 school-attending adolescents (13-21 years rated their health in the Young-HUNT 1 Study (90% response rate in 1995-1997. High school dropout or completion, was defined with the Norwegian National Education Database in the calendar year the participant turned 24 years old. Parental socioeconomic status was defined by using linkages to the National Education Database, the National Insurance Administration and the HUNT2 Survey. We used logistic regression to estimate odds ratios and risk differences of high school dropout, both in the whole population and among siblings within families differentially exposed to health problems. RESULTS: All explored health dimensions were strongly associated with high school dropout. In models adjusted for parental socioeconomic status, the risk differences of school dropout according to health exposures varied between 3.6% (95% CI 1.7 to 5.5 for having ≥ 1 somatic disease versus none and 11.7% (6.3 to 17.0 for being obese versus normal weight. The results from the analyses comparing differentially exposed siblings, confirmed these results with the exception of weaker associations for somatic diseases and psychological distress. School dropout was strongly clustered within families (family level conditional intraclass correlation 0.42. CONCLUSIONS: Adolescent health problems are markers for high school dropout, independent of parental socioeconomic status. Although school dropout it strongly related to family-level factors, also siblings with poor health have reduced opportunity to complete high school compared to

  12. CORONAL SOURCES, ELEMENTAL FRACTIONATION, AND RELEASE MECHANISMS OF HEAVY ION DROPOUTS IN THE SOLAR WIND

    Energy Technology Data Exchange (ETDEWEB)

    Weberg, Micah J. [PhD Candidate in Space Science, Department of Atmospheric, Oceanic, and Space Sciences, University of Michigan, 2134A Space Research Building, 2455 Hayward Street, Ann Arbor, MI 48109-2143, USA. (United States); Lepri, Susan T. [Associate Professor, Department of Atmospheric, Oceanic, and Space Sciences, University of Michigan, 2429 Space Research Building, 2455 Hayward Street, Ann Arbor, MI 48109-2143, USA. (United States); Zurbuchen, Thomas H., E-mail: mjweberg@umich.edu, E-mail: slepri@umich.edu, E-mail: thomasz@umich.edu [Professor, Space Science and Aerospace Engineering, Associate Dean for Entrepreneurship Senior Counselor of Entrepreneurship Education, Department of Atmospheric, Oceanic, and Space Sciences, University of Michigan, 2431 Space Research Building, 2455 Hayward Street, Ann Arbor, MI 48109-2143, USA. (United States)

    2015-03-10

    The elemental abundances of heavy ions (masses larger than He) in the solar wind provide information about physical processes occurring in the corona. Additionally, the charge state distributions of these heavy ions are sensitive to the temperature profiles of their respective source regions in the corona. Heavy ion dropouts are a relatively new class of solar wind events identified by both elemental and ionic charge state distributions. We have shown that their origins lie in large, closed coronal loops where processes such as gravitational settling dominate and can cause a mass-dependent fractionation pattern. In this study we consider and attempt to answer three fundamental questions concerning heavy ion dropouts: (1) 'where are the source loops located in the large-scale corona?'; (2) 'how does the interplay between coronal processes influence the end elemental abundances?'; and (3) 'what are the most probable release mechanisms'? We begin by analyzing the temporal and spatial variability of heavy ion dropouts and their correlation with heliospheric plasma and magnetic structures. Next we investigate the ordering of the elements inside dropouts with respect to mass, ionic charge state, and first ionization potential. Finally, we discuss these results in the context of the prevailing solar wind theories and the processes they posit that may be responsible for the release of coronal plasma into interplanetary space.

  13. LED Current Balance Using a Variable Voltage Regulator with Low Dropout vDS Control

    Directory of Open Access Journals (Sweden)

    Hung-I Hsieh

    2017-02-01

    Full Text Available A cost-effective light-emitting diode (LED current balance strategy using a variable voltage regulator (VVR with low dropout vDS control is proposed. This can regulate the multiple metal-oxide-semiconductor field-effect transistors (MOSFETs of the linear current regulators (LCR, maintaining low dropout vDS on the flat vGS-characteristic curves and making all drain currents almost the same. Simple group LCRs respectively loaded with a string LED are employed to implement the theme. The voltage VVdc from a VVR is synthesized by a string LED voltage NvD, source voltage vR, and a specified low dropout vDS = VQ. The VVdc updates instantly, through the control loop of the master LCR, which means that all slave MOSFETs have almost the same biases on their flat vGS-characteristic curves. This leads to all of the string LED currents being equal to each other, producing an almost even luminance. An experimental setup with microchip control is built to verify the estimations. Experimental results show that the luminance of all of the string LEDs are almost equal to one another, with a maximum deviation below 1% during a wide dimming range, while keeping all vDS of the MOSFETs at a low dropout voltage, as expected.

  14. Resistances to Scientific Knowledge Production of Comparative Measurements of Dropout and Completion in European Higher Education

    Science.gov (United States)

    Carlhed, Carina

    2017-01-01

    The article is a critical sociological analysis of current transnational practices on creating comparable measurements of dropout and completion in higher education and the consequences for the conditions of scientific knowledge production on the topic. The analysis revolves around questions of epistemological, methodological and symbolic types…

  15. Dropout Prevention in Middle and High Schools: From Research to Practice

    Science.gov (United States)

    Wilkins, Julia; Bost, Loujeania Williams

    2016-01-01

    Based on work with state and local education agencies in dropout prevention for students with disabilities, successful research-based interventions are described along with details of how these interventions have been implemented in middle and high schools across the country. The interventions that have helped students with disabilities graduate…

  16. Ethnic minority youth in youth mental health care : utilization and dropout

    NARCIS (Netherlands)

    Haan, Anna Marte de

    2014-01-01

    This thesis focuses on differences between ethnic groups in youth mental health care (YMHC). Three subjects are elaborated: utilization of YMHC, given diagnoses in YMHC, and premature termination (dropout) of therapy in YMHC. The utilization of YMHC services is unequally distributed over different

  17. Can Social-Emotional Learning Reduce School Dropout in Developing Countries?

    Science.gov (United States)

    Wang, Huan; Chu, James; Loyalka, Prashant; Xin, Tao; Shi, Yaojiang; Qu, Qinghe; Yang, Chu

    2016-01-01

    An alarming number of students drop out of junior high school in developing countries. In this study, we examine the impacts of providing a social-emotional learning (SEL) program on the dropout behavior and learning anxiety of students in the first two years of junior high. We do so by analyzing data from a randomized controlled trial involving…

  18. Pseudo-empirical Likelihood-Based Method Using Calibration for Longitudinal Data with Drop-Out.

    Science.gov (United States)

    Chen, Baojiang; Zhou, Xiao-Hua; Chan, Kwun Chuen Gary

    2015-01-01

    In observational studies, interest mainly lies in estimation of the population-level relationship between the explanatory variables and dependent variables, and the estimation is often undertaken using a sample of longitudinal data. In some situations, the longitudinal data sample features biases and loss of estimation efficiency due to non-random drop-out. However, inclusion of population-level information can increase estimation efficiency. In this paper we propose an empirical likelihood-based method to incorporate population-level information in a longitudinal study with drop-out. The population-level information is incorporated via constraints on functions of the parameters, and non-random drop-out bias is corrected by using a weighted generalized estimating equations method. We provide a three-step estimation procedure that makes computation easier. Some commonly used methods are compared in simulation studies, which demonstrate that our proposed method can correct the non-random drop-out bias and increase the estimation efficiency, especially for small sample size or when the missing proportion is high. In some situations, the efficiency improvement is substantial. Finally, we apply this method to an Alzheimer's disease study.

  19. Patterns of Drug Use among Mexican-American Potential School Dropouts.

    Science.gov (United States)

    Bruno, James E.; Doscher, Lynn

    1979-01-01

    Studies a sample of Mexican-American students identified as potential dropouts and finds drug use is widespread. Cigarettes, marijuana, and alcohol are used by the majority of students. "Social" drugs are used more often. Students do not think that general drug use causes social problems; however, girls' attitudes differ from boys'. (Author/BEF)

  20. Joint partially linear model for longitudinal data with informative drop-outs.

    Science.gov (United States)

    Kim, Sehee; Zeng, Donglin; Taylor, Jeremy M G

    2017-03-01

    In biomedical research, a steep rise or decline in longitudinal biomarkers may indicate latent disease progression, which may subsequently cause patients to drop out of the study. Ignoring the informative drop-out can cause bias in estimation of the longitudinal model. In such cases, a full parametric specification may be insufficient to capture the complicated pattern of the longitudinal biomarkers. For these types of longitudinal data with the issue of informative drop-outs, we develop a joint partially linear model, with an aim to find the trajectory of the longitudinal biomarker. Specifically, an arbitrary function of time along with linear fixed and random covariate effects is proposed in the model for the biomarker, while a flexible semiparametric transformation model is used to describe the drop-out mechanism. Advantages of this semiparametric joint modeling approach are the following: 1) it provides an easier interpretation, compared to standard nonparametric regression models, and 2) it is a natural way to control for common (observable and unobservable) prognostic factors that may affect both the longitudinal trajectory and the drop-out process. We describe a sieve maximum likelihood estimation procedure using the EM algorithm, where the Akaike information criterion (AIC) and Bayesian information criterion (BIC) are considered to select the number of knots. We show that the proposed estimators achieve desirable asymptotic properties through empirical process theory. The proposed methods are evaluated by simulation studies and applied to prostate cancer data. © 2016, The International Biometric Society.

  1. The Association between Financial Aid Availability and the College Dropout Rates in Colombia

    Science.gov (United States)

    Melguizo, Tatiana; Torres, Fabio Sanchez; Jaime, Haider

    2011-01-01

    The main objective of this study is to estimate the association between financial aid and college dropout rates of postsecondary students in Colombia. We use a unique dataset from the Colombian Ministry of Education that includes all enrolled college students in the country between 1998 and 2008. Logistic regression is used to identify the…

  2. Can countertransference at the early stage of trauma care predict patient dropout of psychiatric treatment?

    Science.gov (United States)

    Silveira Júnior, Erico de Moura; Polanczyk, Guilherme Vanoni; Hauck, Simone; Eizirik, Cláudio Laks; Ceitlin, Lúcia Helena Freitas

    2011-12-01

    To investigate the association between feelings of countertransference (CT) at the early psychiatric care provided to trauma victims and treatment outcome. The Assessment of Countertransference Scale was used to access CT after the first medical appointment. Fifty psychiatric residents cared for 131 trauma victims of whom 83% were women, aged 15 to 64 years. Patients had been consecutively selected over 4 years. Were evaluated the clinical and demographic characteristics of patients and the correlation with the therapists' CT feelings. Patients were followed-up during treatment to verify the association between initial CT and treatment outcome, defined as discharge and dropout. The median number of appointments was 5 [4; 8], absences 1 [0; 1], and the dropout rate was 34.4%. Both groups, namely the discharge group and the dropout group, shared similar clinical and demographic characteristics. A multivariate analysis identified that patients with a reported history of childhood trauma were 61% less likely to dropout from treatment than patients with no reported history of childhood trauma (OR = 0.39, p = 0.039, CI95% 0.16-0.95). There was no association between initial CT and treatment outcome. In this sample, CT in the initial care of trauma victims was not associated with treatment outcome. Further studies should assess changes in CT during treatment, and how such changes impact treatment outcome.

  3. Technologies for a content and language integrated approach to dropout problems in Higher Education

    NARCIS (Netherlands)

    Marjolein Simons; Dr. Hajer Maaike; Ton Koenraad; Rintse van der Werf

    2006-01-01

    This paper reports on CATS (2006-2007), a project initiated by the Research Centre ‘Teaching in Multicultural Schools’, that addresses language related dropout problems of both native and non-native speakers of Dutch in higher education. The project’s main objective is to develop a model for the

  4. Accelerating the Learning of Low-Achieving Students: The Transformation of a Dropout

    Science.gov (United States)

    Finnan, Christine; Chasin, Gene

    2007-01-01

    Anthony, a stocky, muscular, young African American man with a smile that exudes warmth and enthusiasm, chose a path taken by far too many of his peers: he became a high school dropout. He started down this path long before he entered his urban high school in Wisconsin in 1997. Throughout his years in school, he had never been pushed to excel, and…

  5. Predicting Dropout Student: An Application of Data Mining Methods in an Online Education Program

    Science.gov (United States)

    Yukselturk, Erman; Ozekes, Serhat; Turel, Yalin Kilic

    2014-01-01

    This study examined the prediction of dropouts through data mining approaches in an online program. The subject of the study was selected from a total of 189 students who registered to the online Information Technologies Certificate Program in 2007-2009. The data was collected through online questionnaires (Demographic Survey, Online Technologies…

  6. Academic Mentoring and Dropout Prevention for Students in Math, Science and Technology

    Science.gov (United States)

    Larose, Simon; Cyrenne, Diane; Garceau, Odette; Harvey, Marylou; Guay, Frederic; Godin, Fanny; Tarabulsy, George M; Deschenes, Claire

    2011-01-01

    In this study, we examined the impact of a new academic mentoring program aimed at preventing student dropout in math, science and technology. The MIRES program entails bimonthly meetings between students entering college and university students completing their undergraduate degree in science and engineering. A randomized pretest-posttest control…

  7. The Impact of Child Labor and School Dropout on Human Capital: Gender Differences in Mexico.

    Science.gov (United States)

    Knaul, Felicia Marie

    This chapter, Chapter 2 in "the Economics of Gender in Mexico," uses retrospective household survey data from Mexico to assess the long-term impacts of school dropout and of working early in life, in terms of adult labor market returns. Through these data, it is possible to link adult wages to the ages at which individuals started…

  8. Predicting School Dropout and Adolescent Sexual Behavior in Offspring of Depressed and Nondepressed Mothers

    Science.gov (United States)

    Bohon, Cara; Garber, Judy; Horowitz, Jason L.

    2007-01-01

    Objective: To examine predictors of school dropout and adolescent sexual behavior in offspring of depressed and nondepressed mothers. Possible moderators of the relation between maternal depression and these outcomes also were explored. Method: Participants were 240 mothers and adolescents assessed annually from 6th through 12th grade. Interviews…

  9. The Effects of the Introduction of Bachelor Degrees on College Enrollment and Dropout Rates

    Science.gov (United States)

    Horstschräer, Julia; Sprietsma, Maresa

    2015-01-01

    We estimate the short-term effects of the introduction of the Bachelor degree system in Germany, a change in degree regulations such that students need less time to earn a first degree, on college enrollment and dropout rates. We use variation in the timing of the reform at the university department level to identify the effects of the reform…

  10. Refining success and dropout in massive open online courses based on the intention–behaviour gap

    NARCIS (Netherlands)

    Henderikx, Maartje; Kreijns, Karel; Kalz, Marco

    2017-01-01

    In this paper we present an alternative typology for determining success and dropout in massive open online courses (MOOCs). This typology takes the perspectives of MOOC-takers into account and is based on the their intentions and subsequent behaviour. An explorative study using two MOOCs was

  11. Dumping Ground or Effective Alternative: Dropout Prevention Programs in Urban Schools.

    Science.gov (United States)

    Groth, Cori

    1998-01-01

    An alternative dropout-prevention program is examined from the students' perspectives. Findings from interviews and observations suggest that the program is effective in keeping the students in school but does little to help the students develop daily living and social skills. Policy implications are discussed and suggestions for future research…

  12. High school dropouts in emerging adulthood: substance use, mental health problems, and crime.

    Science.gov (United States)

    Maynard, Brandy R; Salas-Wright, Christopher P; Vaughn, Michael G

    2015-04-01

    This study examined the distribution of substance use, mental health, and criminal behavior among dropouts derived from a nationally representative sample of 18-25 year old (N = 19,312) emerging adults in the United States. Using public-use data from the 2010 National Survey on Drug Use and Health, this study employed multiple logistic regression with adjustments for complex survey sampling and compared high school dropouts with graduates with respect to substance use, mental health, and criminal behavior. After controlling for the effects of age, gender, race/ethnicity, family income, receipt of government assistance, employment status, and metropolitan population density, dropouts were more likely to meet criteria for nicotine dependence and report daily cigarette use, and more likely to report having attempted suicide in the previous year, been arrested for larceny, assault, drug possession or drug sales relative to their high school graduate counterparts. The findings of this study provide important insights and an initial epidemiologic portrait of mental health, substance use, and criminal behaviors of dropouts during emerging adulthood.

  13. Allelic drop-out probabilities estimated by logistic regression--Further considerations and practical implementation

    DEFF Research Database (Denmark)

    Tvedebrink, Torben; Eriksen, Poul Svante; Asplund, Maria

    2012-01-01

    We discuss the model for estimating drop-out probabilities presented by Tvedebrink et al. [7] and the concerns, that have been raised. The criticism of the model has demonstrated that the model is not perfect. However, the model is very useful for advanced forensic genetic work, where allelic dro...

  14. Comparison of Different LGM-Based Methods with MAR and MNAR Dropout Data

    Directory of Open Access Journals (Sweden)

    Meijuan Li

    2017-05-01

    Full Text Available The missing not at random (MNAR mechanism may bias parameter estimates and even distort study results. This study compared the maximum likelihood (ML selection model based on missing at random (MAR mechanism and the Diggle–Kenward selection model based on MNAR mechanism for handling missing data through a Monte Carlo simulation study. Four factors were considered, including the missingness mechanism, the dropout rate, the distribution shape (i.e., skewness and kurtosis, and the sample size. The results indicated that: (1 Under the MAR mechanism, the Diggle–Kenward selection model yielded similar estimation results with the ML approach; Under the MNAR mechanism, the results of ML approach were underestimated, especially for the intercept mean and intercept slope (μi and μs. (2 Under the MAR mechanism, the 95% CP of the Diggle–Kenward selection model was lower than that of the ML method; Under the MNAR mechanism, the 95% CP for the two methods were both under the desired level of 95%, but the Diggle–Kenward selection model yielded much higher coverage probabilities than the ML method. (3 The Diggle–Kenward selection model was easier to be influenced by the non-normal degree of target variable's distribution than the ML approach. The level of dropout rate was the major factor affecting the parameter estimation precision, and the dropout rate-induced difference of two methods can be ignored only when the dropout rate falls below 10%.

  15. Socio-ecological predictors of participation and dropout in organised sports during childhood.

    Science.gov (United States)

    Vella, Stewart A; Cliff, Dylan P; Okely, Anthony D

    2014-05-13

    The purpose of this study was to explore the socio-ecological determinants of participation and dropout in organised sports in a nationally-representative sample of Australian children. Data were drawn from Waves 3 and 4 of the Longitudinal Study of Australian Children. In total, 4042 children aged 8.25 (SD = 0.44) years at baseline were included, with 24-months between Waves. Socio-ecological predictors were reported by parents and teachers, while cognitive and health measures were assessed by trained professionals. All predictors were assessed at age 8, and used to predict participation and dropout by age 10. Seven variables at age 8 were shown to positively predict participation in organised sports at age 10. These included: sex (boy); fewer people in household; higher household income; main language spoken at home (English); higher parental education; child taken to a sporting event; and, access to a specialist PE teacher during primary school. Four variables predicted dropout from organised sports by age 10: lower household income; main language spoken at home (non-English); lower parental education; and, child not taken to a sporting event. The interplay between child sex, socioeconomic indicators, and parental support is important in predicting children's participation in organised sports. Multilevel and multicomponent interventions to promote participation and prevent dropout should be underpinned by the Socio-Ecological Model and targeted to high risk populations using multiple levels of risk.

  16. Predictors of dropout from internet-based self-help cognitive behavioral therapy for insomnia.

    Science.gov (United States)

    Yeung, Wing-Fai; Chung, Ka-Fai; Ho, Fiona Yan-Yee; Ho, Lai-Ming

    2015-10-01

    Dropout from self-help cognitive-behavioral therapy for insomnia (CBT-I) potentially diminishes therapeutic effect and poses clinical concern. We analyzed the characteristics of subjects who did not complete a 6-week internet-based CBT-I program. Receiver operator characteristics (ROC) analysis was used to identify potential variables and cutoff for predicting dropout among 207 participants with self-report insomnia 3 or more nights per week for at least 3 months randomly assigned to self-help CBT-I with telephone support (n = 103) and self-help CBT-I (n = 104). Seventy-two participants (34.4%) did not complete all 6 sessions, while 42 of the 72 (56.9%) dropped out prior to the fourth session. Significant predictors of non-completion are total sleep time (TST) ≥ 6.82 h, Hospital Anxiety and Depression Scale depression score ≥ 9 and Insomnia Severity Index score self-help CBT-I, in contrast to shorter TST as a predictor in 2 studies of face-to-face CBT-I, while greater severity of depression predicts dropout in both this study and a study of face-to-face CBT-I. Strategies for minimizing dropout from internet-based CBT-I are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Family Background and University Dropouts during the Crisis: The Case of Italy

    Science.gov (United States)

    Ghignoni, Emanuela

    2017-01-01

    The Italian university system has long been characterised by high non-completion rates, though aggregate data show a slight reduction of dropouts in recent years. The most straightforward theoretical explanation for this lies in the lowering opportunity cost of studying due to the financial and economic crisis. Nonetheless, this interpretation is…

  18. Disentangling the Weight of School Dropout Predictors: A Test on Two Longitudinal Samples.

    Science.gov (United States)

    Janosz, Michel; LeBlanc, Marc; Boulerice, Bernard; Tremblay, Richard E.

    1997-01-01

    Predictors of school dropout and their stability over time were studied in 791 white French-speaking Canadian students aged 12 to 16 years in 1974 and 791 similar students in 1985 through self-administered questionnaires. School, family, behavioral, social, and personality variables predicted dropping out in both samples, and these predictors were…

  19. Prevention of School Dropout through the Reduction of Disruptive Behaviors and School Failure in Elementary School.

    Science.gov (United States)

    Vitaro, Frank; Brendgen, Mara; Tremblay, Richard E.

    1999-01-01

    Reports the effects of a preventive intervention program on dropping out of school in a sample of disruptive boys from low socioeconomic status. Results show that the program had an indirect effect on later school dropout problems through its impact on grade retention/special education placement. The reduction of grade retention/special classroom…

  20. Children's educational completion rates and dropouts in the context of Ethiopia's national poverty reduction strategy

    NARCIS (Netherlands)

    Woldehanna, T.

    2008-01-01

    Using a young Lives project data, a combination of quantitative and qualitative method was used to analyse the determinants of school completion/dropout of children from primary education. A Cox box proportional hazard model was used analyse the survival of children in primary education. The

  1. Dropout rates in couples undergoing in vitro fertilization and intrauterine insemination

    NARCIS (Netherlands)

    Bensdorp, Alexandra J.; Tjon-Kon-Fat, Raissa; Verhoeve, Harold; Koks, Carolien; Hompes, Peter; Hoek, Annemieke; de Bruin, Jan Peter; Cohlen, Ben; Hoozemans, Diederik; Broekmans, Frank; van Bomme, Peter; Smeenk, Jesper; Mol, Ben W. J.; van der Veen, Fulco; van Wely, Madelon

    2016-01-01

    Objective: To compare dropout rates in couples undergoing conventional in vitro fertilization with single embryo transfer (IVF-SET), in vitro fertilization in a modified natural cycle (IVF-MNC) or intrauterine insemination with ovarian stimulation (IUI-OS). Study design: Secondary analysis of a

  2. Discriminating Factors between Completers of and Dropouts from Online Learning Courses

    Science.gov (United States)

    Lee, Youngju; Choi, Jaeho; Kim, Taehyun

    2013-01-01

    This study examined the differences between persistent and dropout students enrolled in an online course with five factors: support from family and work, academic locus of control, academic self-efficacy, time and environment management skills, and metacognitive self-regulation skills. Moreover, this study investigated the most significant factors…

  3. Do GED Recipients Differ from Graduates and School Dropouts?: Findings from an Inner-City Cohort

    Science.gov (United States)

    Ou, Suh-Ruu

    2008-01-01

    The differences in income, crime, health, mental health, and substance use among high school dropouts, GED recipients, and high school graduates are investigated. The study sample is drawn from the Chicago Longitudinal Study (CLS), an ongoing investigation of a panel of low-income minority children who grew up in the inner city. After controlling…

  4. Dropout Prediction in E-Learning Courses through the Combination of Machine Learning Techniques

    Science.gov (United States)

    Lykourentzou, Ioanna; Giannoukos, Ioannis; Nikolopoulos, Vassilis; Mpardis, George; Loumos, Vassili

    2009-01-01

    In this paper, a dropout prediction method for e-learning courses, based on three popular machine learning techniques and detailed student data, is proposed. The machine learning techniques used are feed-forward neural networks, support vector machines and probabilistic ensemble simplified fuzzy ARTMAP. Since a single technique may fail to…

  5. Socio-ecological predictors of participation and dropout in organised sports during childhood

    Science.gov (United States)

    2014-01-01

    Background The purpose of this study was to explore the socio-ecological determinants of participation and dropout in organised sports in a nationally-representative sample of Australian children. Methods Data were drawn from Waves 3 and 4 of the Longitudinal Study of Australian Children. In total, 4042 children aged 8.25 (SD = 0.44) years at baseline were included, with 24-months between Waves. Socio-ecological predictors were reported by parents and teachers, while cognitive and health measures were assessed by trained professionals. All predictors were assessed at age 8, and used to predict participation and dropout by age 10. Results Seven variables at age 8 were shown to positively predict participation in organised sports at age 10. These included: sex (boy); fewer people in household; higher household income; main language spoken at home (English); higher parental education; child taken to a sporting event; and, access to a specialist PE teacher during primary school. Four variables predicted dropout from organised sports by age 10: lower household income; main language spoken at home (non-English); lower parental education; and, child not taken to a sporting event. Conclusions The interplay between child sex, socioeconomic indicators, and parental support is important in predicting children’s participation in organised sports. Multilevel and multicomponent interventions to promote participation and prevent dropout should be underpinned by the Socio-Ecological Model and targeted to high risk populations using multiple levels of risk. PMID:24885978

  6. Refining Success and Dropout in MOOCs Based on the Intention-Behaviour Gap

    NARCIS (Netherlands)

    Henderikx, Maartje; Kreijns, Karel; Kalz, Marco

    2016-01-01

    Currently success measurement of MOOCs is certificate- and completion-centric and fails to take student intention into account. This results in high dropout rates of 90-95%. While this view of success has been critiqued by the research community, no suitable alternative has yet been developed. This

  7. Institutional Characteristics and College Student Dropout Risks: A Multilevel Event History Analysis

    Science.gov (United States)

    Chen, Rong

    2012-01-01

    In the past two decades, although access to higher education for American students has improved, student persistence in 4-year institutions is far from assured. There have been a number of research studies on student persistence/dropout in higher education, but most have focused on the characteristics and behavior of students as illustrated by the…

  8. Preventing Dropouts: The Important Role of Afterschool. Afterschool Alert. Issue Brief No. 60

    Science.gov (United States)

    Afterschool Alliance, 2013

    2013-01-01

    Over the last decade, high school dropout rates have declined to single digits nationally. However, the U.S. only ranks 22nd in high school graduation rates and 14th in college attainment among industrialized countries. Furthermore, graduation gaps persist among students from lower socioeconomic backgrounds and minority racial groups. Reducing…

  9. A Comparative Analysis of the Causes of Primary School Dropout in ...

    African Journals Online (AJOL)

    This study sought to compare the causes of school dropout in a commercial farm setting and an urban setting. The sample for the study consisted of forty teachers (twenty from each setting) drawn from two urban schools and three commercial farm schools, twenty parents/ caregivers (ten from each setting), forty pupils ...

  10. Do School Budgets Matter? The Effect of Budget Referenda on Student Dropout Rates

    Science.gov (United States)

    Lee, Kyung-Gon; Polachek, Solomon W.

    2018-01-01

    This paper analyzes how changes in school expenditures affect dropout rates based on data from 466 school districts in New York during the 2003/04 to the 2007/08 school years. Past traditional regression approaches show mixed results in part because school expenditures are likely endogenous, so that one cannot disentangle cause and effect. The…

  11. Determining Relationships between Predictive Factors of High School Dropout and Student Engagement

    Science.gov (United States)

    Meagher, Jennifer L.

    2010-01-01

    Over the past several years, educational leaders and researchers have tried to find the causes for high school dropout. Studies have shown that both demographic and student factors have contributed to placing a student at risk for dropping out of high school. Most of the studies, however, have been conducted in urban or suburban settings.…

  12. Why Did the Black-White Dropout Gap Widen in the 2000s?

    Science.gov (United States)

    Suh, Suhyun; Malchow, Ashley; Suh, Jingyo

    2014-01-01

    This research investigates causes of the widening Black-White gap in dropout rates during the 2000s using two cohorts of National Longitudinal Surveys of Youth, NLSY79 and NLSY97. The authors found four factors which contributed to the widening of the Black-White gap: school suspension policies, peer impact, fatherless households, and the…

  13. The Effects of Runaway-Homeless Episodes on High School Dropout

    Science.gov (United States)

    Aratani, Yumiko; Cooper, Janice L.

    2015-01-01

    This article uses data from the National Longitudinal Survey of Youth 1997 to examine the relationship between running away from home between the ages of 12 and 14 and dropping from high school among youth. Propensity score matching was conducted in estimating the effect of running away on high school dropout while controlling for confounding…

  14. The long-term effects of school dropout and GED attainment on substance use disorders.

    Science.gov (United States)

    Reingle Gonzalez, Jennifer M; Salas-Wright, Christopher P; Connell, Nadine M; Jetelina, Katelyn K; Clipper, Stephen J; Businelle, Michael S

    2016-01-01

    Epidemiologic research suggests that 14% of the population do not complete high school, and dropout has been linked to mental health conditions, substance use, chronic health problems, and criminal behavior. Few studies have assessed whether attainment of the general education development (GED) credential is protective from substance use. To assess the long-term outcomes of school dropout and GED attainment on past year substance use disorders, age of onset, and current smoking status. Longitudinal data were included for lifetime substance users who participated in the National Epidemiological Survey on Alcohol and Related Conditions (Waves I and II). Eligible participants (N=30,608) were classified as having completed high school, dropped out of high school and did not complete a GED, or completed GED at Wave I. Survey logistic regression analyses were used to determine whether high school graduation status was associated with substance use disorders and smoking at Wave II. Multivariate results suggest that participants who dropped out of high school (OR=1.53; pschool graduates. High school dropouts were also more likely to be current smokers (OR=1.88; pschool dropouts have higher long-term rates of marijuana use disorder and smoking in adulthood than graduates. Attainment of a GED does not appear to be protective from marijuana use disorders in adulthood. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  15. School Dropout, Problem Behaviour and Poor Academic Achievement: A Longitudinal View of Portuguese Male Offenders

    Science.gov (United States)

    Beatriz Saraiva, A.; Pereira, Beatriz O.; Zamith-Cruz, Judite

    2011-01-01

    This study examines school dropouts from the perspective of male adults themselves through interviews with offenders currently serving sentences. Participants were 10 Portuguese male inmates, between the ages of 19 and 46 years of age, incarcerated in two prison facilities on the Azores. Qualitative and interpretative methods were carried out…

  16. Longitudinal Examination of Aggression and Study Skills from Middle to High School: Implications for Dropout Prevention

    Science.gov (United States)

    Orpinas, Pamela; Raczynski, Katherine; Hsieh, Hsien-Lin; Nahapetyan, Lusine; Horne, Arthur M.

    2018-01-01

    Background: High school completion provides health and economic benefits. The purpose of this study is to describe dropout rates based on longitudinal trajectories of aggression and study skills using teacher ratings. Methods: The sample consisted of 620 randomly selected sixth graders. Every year from Grade 6 to 12, a teacher completed a…

  17. Relationships between Parenting Practices, Social Engagement, Academic Competency, and High School Dropout

    Science.gov (United States)

    Bedrossian, Alfred

    2017-01-01

    The purpose of this study was to investigate the relationships between parenting practices, social engagement, academic competency, and high school dropout. The study revealed students whose parents practiced Reactive Communication along with students that exhibited Truancy and Disciplinary Issues were more likely to drop out. Conversely, students…

  18. Rebound in Dropout Rates as a Result of Rural School Consolidation

    Science.gov (United States)

    Haibo, Yu

    2013-01-01

    Rural school consolidation has significantly changed the landscape of rural education in China. Based on a study carried out in nine provinces, this article analyzes the effect of this policy initiative. It has led to increased school dropout rates in rural schools.

  19. A systematic review of the relationship between high school dropout and substance use.

    Science.gov (United States)

    Townsend, Loraine; Flisher, Alan J; King, Gary

    2007-12-01

    A systematic review of peer-reviewed, empirical literature published between 1990 and 2006 was undertaken to determine whether existing research could provide evidence, and a deeper understanding of the relationship between dropping out of high school and the use of substances such as tobacco, alcohol, cannabis/marijuana and other illicit drugs. Forty-six articles were reviewed. The review describes the heterogeneity of theoretical frameworks employed, as well as the limited ability of any one to adequately explain the relationship between high school dropout and substance use. A refinement of the many confounding and mediating variables into coherent conceptual categories would aid more robust theory building and theory integration. In spite of differences in dropout definitions and diverse measures of substance use across studies, the main findings point to a largely consistent relationship between dropping out of high school and substance use. However, socially disadvantaged and poor persons, dropouts, and drug users are over-represented in some of the loss to follow-up groups in longitudinal studies surveyed. More rigorous mechanisms to retain participants in longitudinal studies should be employed. Suggestions for future research include comparisons between urban and rural populations, employing qualitative research methods, and research in developing countries, which have the least favourable school outcomes and a dearth of research on high school dropout.

  20. School Dropout Pattern among Senior Secondary Schools in Delta State, Nigeria

    Science.gov (United States)

    Ajaja, O. Patrick

    2012-01-01

    The major purpose of this study was to determine the pattern of dropout among secondary school students in Delta State. To guide this study, 7 research questions were asked and answered, 3 hypotheses stated and tested at 0.05 level of significance. The design of study was ex post facto using the past school attendance registers as the major…

  1. The Effects of Transitional Challenges on Ninth-Grade School Dropouts

    Science.gov (United States)

    Jones, Merlene Leona

    2017-01-01

    The high dropout rate of the United States Virgin Islands school district's ninth-grade students is a major educational problem and the catalyst for a myriad of social problems. Ninth grade academies and extended school day intervention programs have benefited only the academically prepared students. This qualitative case study examined educators'…

  2. Salient Predictors of School Dropout among Secondary Students with Learning Disabilities

    Science.gov (United States)

    Doren, Bonnie; Murray, Christopher; Gau, Jeff M.

    2014-01-01

    The purpose of this study was to identify the unique contributions of a comprehensive set of predictors and the most salient predictors of school dropout among a nationally representative sample of students with learning disabilities (LD). A comprehensive set of theoretically and empirically relevant factors was selected for examination. Analyses…

  3. High School Dropout, Graduation, and Completion Rates: Better Data, Better Measures, Better Decisions

    Science.gov (United States)

    Hauser, Robert M., Ed.; Koenig, Judith Anderson, Ed.

    2011-01-01

    High school graduation and dropout rates have long been used as indicators of educational system productivity and effectiveness and of social and economic well being. While determining these rates may seem like a straightforward task, their calculation is in fact quite complicated. How does one count a student who leaves a regular high school but…

  4. Adolescent behavioral, affective, and cognitive engagement in school: relationship to dropout.

    Science.gov (United States)

    Archambault, Isabelle; Janosz, Michel; Morizot, Julien; Pagani, Linda

    2009-09-01

    High school dropout represents an important public health issue. This study assessed the 3 distinct dimensions of student engagement in high school and examined the relationships between the nature and course of such experiences and later dropout. We administered questionnaires to 13,330 students (44.7% boys) from 69 high schools in the province of Quebec (Canada). During 3 consecutive high school years, students reported their behavioral, emotional, and cognitive engagement to school. Information on later dropout status was obtained through official records. Although many adolescents remained highly engaged in high school, one third reported changes, especially decreases in rule compliance, interest in school, and willingness to learn. Students reporting low engagement or important decrements in behavioral investment from the beginning of high school presented higher risks of later dropout. School-based interventions should address the multiple facets of high school experiences to help adolescents successfully complete their basic schooling. Creating a positive social-emotional learning environment promises better adolescent achievement and, in turn, will contribute to a healthier lifestyle.

  5. Predicting Secondary School Dropout among South African Adolescents: A Survival Analysis Approach

    Science.gov (United States)

    Weybright, Elizabeth H.; Caldwell, Linda L.; Xie, Hui; Wegner, Lisa; Smith, Edward A.

    2017-01-01

    Education is one of the strongest predictors of health worldwide. In South Africa, school dropout is a crisis where by Grade 12, only 52% of the age appropriate population remain enrolled. Survival analysis was used to identify the risk of dropping out of secondary school for male and female adolescents and examine the influence of substance use…

  6. A meta-analysis of the effects of dropout prevention programs on school absenteeism.

    Science.gov (United States)

    Tanner-Smith, Emily E; Wilson, Sandra Jo

    2013-10-01

    This study reports findings from a systematic review and meta-analysis of literature examining the effects of school dropout prevention and intervention programs on students' school absenteeism outcomes. The meta-analysis synthesized 74 effect sizes measuring posttest differences in school absenteeism outcomes for youth enrolled in dropout prevention programs relative to a comparison group. Although results from randomized controlled trials indicated significant beneficial program effects, findings from quasi-experimental studies indicated no significant beneficial or detrimental effects. Examination of study characteristics suggested that dropout programs may have beneficial effects on school absenteeism among primarily male samples, and younger samples. Although no single type of intervention program was consistently more effective than others, vocational oriented and supplemental academic training programs showed some promise. However, the inconsistency in results and the possibility of small study bias mean the quality of evidence in this literature is low; at this time there is not enough evidence to conclude that dropout prevention programs have a universal impact on youth's school absenteeism outcomes.

  7. Primary and Secondary Education in Morocco: From Access to School into Generalization to Dropout

    Science.gov (United States)

    Mansouri, Zoulal; Moumine, Mohamed El Amine

    2017-01-01

    This article provides an overview of school wastage, namely repetition and dropout in primary and secondary schools in Morocco. It describes how this phenomenon has progressed since school was implemented in the 1960s. It shows that the fundamental principles of the education system established in the aftermath of Morocco?s independence in 1956…

  8. The Reasons of School Dropouts in Higher Education: Babaeski Vocational College Case

    Science.gov (United States)

    Can, Ertug; Aktas, Fatma Oya; Arpacioglu, Isil Tuzun

    2017-01-01

    In Turkey, nearly 400.000 higher education students have left university education in the last 3 years. This figure is an indication of a negative situation. Turkey is in the first place in terms of school dropout rates within the European Higher Education Area (EHEA). After completing primary and secondary education and passing the necessary…

  9. School Persistence in the Wake of War: Wartime Experiences, Reintegration Supports, and Dropout in Sierra Leone

    Science.gov (United States)

    Zuilkowski, Stephanie Simmons; Betancourt, Theresa S.

    2014-01-01

    This article examines the relationship of wartime experience and reintegration supports to students' risk of school dropout. It draws on longitudinal, mixed-methods data collected among children and youth in Sierra Leone from 2002 through 2008. The study finds that family financial support and perceived social support are positively associated…

  10. ACE/SWICS OBSERVATIONS OF HEAVY ION DROPOUTS WITHIN THE SOLAR WIND

    Energy Technology Data Exchange (ETDEWEB)

    Weberg, Micah J. [PhD Candidate in Space and Planetary Physics, 2435 Space Research Building, 2455 Hayward Street, Ann Arbor, MI 48109-2143, USA. (United States); Zurbuchen, Thomas H. [Professor, Space Science and Aerospace Engineering, Associate Dean for Entrepreneurship, 2429 Space Research Building, 2455 Hayward Street, Ann Arbor, MI 48109-2143, USA. (United States); Lepri, Susan T., E-mail: mjweberg@umich.edu, E-mail: thomasz@umich.edu, E-mail: slepri@umich.edu [Associate Research Scientist, 2417 Space Research Building, 2455 Hayward Street, Ann Arbor, MI 48109-2143, USA. (United States)

    2012-11-20

    We present the first in situ observations of heavy ion dropouts within the slow solar wind, observed for select elements ranging from helium to iron. For iron, these dropouts manifest themselves as depletions of the Fe/H ratio by factors up to {approx}25. The events often exhibit mass-dependent fractionation and are contained in slow, unsteady wind found within a few days from known stream interfaces. We propose that such dropouts are evidence of gravitational settling within large coronal loops, which later undergo interchange reconnection and become source regions of slow, unsteady wind. Previously, spectroscopic studies by Raymond et al. in 1997 (and later Feldman et al. in 1999) have yielded strong evidence for gravitational settling within these loops. However, their expected in situ signature plasma with heavy elements fractionated by mass was not observed prior to this study. Using data from the SWICS instrument on board the Advanced Composition Explorer (ACE), we investigate the composition of the solar wind within these dropouts and explore long term trends over most of a solar cycle.

  11. School Expulsions, Suspensions, and Dropouts: Understanding the Issues. Hot Topics Series.

    Science.gov (United States)

    Gallegos, Arnold, Ed.

    This collection of papers examines the causal and contextual issues surrounding the emerging rash of student expulsions, suspensions, and dropouts; discusses legal restrictions that school personnel must consider when establishing and implementing student codes of conduct; and presents promising programs and practices to reduce the number of…

  12. Factors influencing high dropout rates of girl child from education: A ...

    African Journals Online (AJOL)

    ... and mothers, achieving gender equality and empowerment of women, curbing the spread of HIV and AIDS and other diseases and improving environmental sustainability. The objectives of the study were to assess the magnitude of school dropout and identify factors influencing this tendency in the North West province.

  13. Drop-out from a drug treatment clinic and associated reasons.

    Science.gov (United States)

    Hoseinie, Leila; Gholami, Zhaleh; Shadloo, Behrang; Mokri, Azarakhsh; Amin-Esmaeili, Masoumeh; Rahimi-Movaghar, Afarin

    2017-05-01

    The aim of this study was to assess drop-out rates and associated reasons among patients at the Iranian National Center for Addiction Studies (INCAS) clinic. In a one-year period (April 2014 to March 2015), all patients with drug dependence who had been referred for treatment and attended for a first assessment were included in this study (N=242). Those who received treatment were followed until March 2016. Survival analysis showed that 70.2% had dropped out from treatment. Log rank test showed that treatment drop-out rates differed between the different approaches used (P < 0.001), with the lowest slope inbuprenorphine maintenance treatment and the highest in the detoxification programme. Drop-out rates within the first three months was 62% (SE= 0.05) and 82.4% (SE=0.03) for opioids and stimulants dependence, respectively. Analyses were performed using SPSS (Version 21.0) and STATA software, (version 13.0). From the patients' perspective, motivational inconsistencies were considered as the main reason for not starting or leaving treatment. The findings of this study could give service providers a better grasp of drop-out rates and the associated reasons.

  14. Is Obesity Associated with School Dropout? Key Developmental and Ethnic Differences

    Science.gov (United States)

    Lanza, H. Isabella; Huang, David Y. C.

    2015-01-01

    Background: We aimed to expand the literature on child obesity and school outcomes by examining associations between obesity and high school dropout, including the role of obesity onset and duration as well as ethnicity. Methods: Data on 5066 children obtained between 1986 and 2010 from the child cohort of the 1979 National Longitudinal Study of…

  15. Re-Examining Participatory Research in Dropout Prevention Planning in Urban Communities

    Science.gov (United States)

    Irby, Decoteau; Mawhinney, Lynnette; Thomas, Kristopher

    2013-01-01

    This paper explores the concept of what a community-based participatory dropout prevention planning process might entail. Specifically, it looks at a year-long research project that brought together formerly incarcerated school non-completers, researchers, and local policy-makers (stakeholders) to address low high-school completion rates in the…

  16. Dropout Rates, Student Momentum, and Course Walls: A New Tool for Distance Education Designers

    Science.gov (United States)

    Christensen, Steven S.; Spackman, Jonathan S.

    2017-01-01

    This paper explores a new tool for instructional designers. By calculating and graphing the Student Momentum Indicator (M) for 196 university-level online courses and by employing the constant comparative method within the grounded theory framework, eight distinct graph shapes emerged as meaningful categories of dropout behavior. Several of the…

  17. A Meta-Analysis of Dropout Prevention Outcomes and Strategies. A Technical Report

    Science.gov (United States)

    Chappell, Shanan L.; O'Connor, Patrick; Withington, Cairen; Stegelin, Dolores A.

    2015-01-01

    Almost from the start of the public schools system in America, students have been leaving school without high school diplomas. However, the dropout issue did not rise to the level of significance it has today until the early 1980s, when social pressures, along with business leaders, leveraged their influence on educators to address the dropout…

  18. A Reason To Stay in School: What Educators Can Do To Reduce Dropout Rates.

    Science.gov (United States)

    Presson, Alice; Bottoms, Gene

    The Southern Regional Education Board (SREB) and the Center on Education and Training for Employment (CETE) at Ohio State University worked with six schools (two comprehensive high schools, two high schools served by an area vocational center, an area vocational center, and a junior high school) in the SREB region to keep potential dropouts in…

  19. Higher Education Drop-out in Spain--Particular Case of Universities in Galicia

    Science.gov (United States)

    Arce, Maria Elena; Crespo, Barbara; Míguez-Álvarez, Carla

    2015-01-01

    The existence of a high university dropout rate in Spain is undeniable. Data shows that approximately one out of five students drop out from college. During the economic expansion period (2001-2007) more students abandoned their studies than during the crisis period (2007-2011). This situation also affects unemployment rates due to the fact that…

  20. Dropout rates in couples undergoing in vitro fertilization and intrauterine insemination

    NARCIS (Netherlands)

    Bensdorp, Alexandra J.; Tjon-Kon-Fat, Raissa; Verhoeve, Harold; Koks, Carolien; Hompes, Peter; Hoek, Annemieke; de Bruin, Jan Peter; Cohlen, Ben; Hoozemans, Diederik; Broekmans, Frank; van Bomme, Peter; Smeenk, Jesper; Mol, Ben W J; van der Veen, Fulco; van Wely, Madelon

    2016-01-01

    Objective To compare dropout rates in couples undergoing conventional in vitro fertilization with single embryo transfer (IVF-SET), in vitro fertilization in a modified natural cycle (IVF-MNC) or intrauterine insemination with ovarian stimulation (IUI-OS). Study design Secondary analysis of a

  1. Development of a Program to Reduce Dropout Rates of Pregnant and Parenting Teens.

    Science.gov (United States)

    Pollack, Andrew M.

    1987-01-01

    Describes a program to reduce the dropout rate for pregnant and parenting teens at York Vocational-Technical School (Pennsylvania) for the second semester of 1985-86. One successful feature was a "caring class" providing information about pregnancy, childcare, nutrition, and other subjects. The program retained most of its enrollees. Includes 1…

  2. Treatment planning: A key milestone to prevent treatment dropout in adolescents with borderline personality disorder.

    Science.gov (United States)

    Desrosiers, Lyne; Saint-Jean, Micheline; Breton, Jean-Jacques

    2015-06-01

    The aim of this study was to gain a broader appreciation of processes involved in treatment dropout in adolescents with borderline personality disorder (BPD). A constructivist grounded theory was chosen using a multiple-case research design with three embedded levels of analysis (adolescent, parent, and care setting). Theoretical sampling and the different stages of analysis specific to grounded theory were performed according to the iterative process of constant comparative analysis. Twelve cases were examined (nine dropouts among adolescents with BPD and for the purpose of falsification, one dropout of suicidal adolescent without BPD and two completed treatments among adolescents with BPD). To document the cases, three groups of informants were recruited (adolescents, parents, and therapists involved in the treatment) and 34 interviews were conducted. Psychological characteristics, perception of mental illness and mental health care, and help-seeking context were the specific treatment dropout vulnerabilities identified in adolescents with BPD and in their parents. However, their disengagement became an issue only when care-setting response--including mitigation of accessibility problems, adaptation of services to needs of adolescents with BPD, preparation for treatment, and concern for clinicians' disposition to treat--was ill-suited to these treatment dropout vulnerabilities. Treatment planning proves to be a key milestone to properly engage adolescents with BPD and their parent. Systematic assessment of treatment dropout vulnerabilities before the intervention plan is laid out could foster better-suited responses of the care setting thus decreasing the incidence of treatment discontinuation in adolescents with BPD. Treatment dropout vulnerabilities specific to adolescents with BPD and their parents can be detected before the beginning of treatment. Premature treatment termination may be prevented if the care setting considers these vulnerabilities at treatment

  3. Comparison of treatment effect across varying severities of meibomian gland dropout.

    Science.gov (United States)

    Turnbull, Philip R K; Misra, Stuti L; Craig, Jennifer P

    2017-09-30

    Better understanding of the pathophysiology of meibomian gland dysfunction (MGD) has provided the opportunity to develop treatments which could be tailored for specific presentations of MGD. This study sought to directly compare treatment effectiveness for three current therapies across differing levels of MG dropout. Subjects (n=81), grouped by infrared meibography dropout proportions, into either no (control), mild, or pronounced MG dropout, were randomised to receive treatment with a latent heat device (n=25), liposomal spray (n=28), or heated warm compress (n=28). A battery of tear film measures was performed, pre- and post-application of treatment, and compared by treatment type and MG severity. Symptoms correlated with MG dropout proportions (r=0.618, p<0.001). Following treatment, non-invasive tear breakup time improved (p=0.010), independent of treatment type (p=0.131). The improvement was significant only in the pronounced MGD group (+4.32 ±1.15s, p=0.008), however, following treatment, the mild group was no longer distinct from the control group (p=0.843). Lipid layer grade (LLG) also improved following treatment (p<0.009), but again was not specific to treatment type (p=0.349). All three severity groups showed an improvement in LLG, with 49.3% of participants showing an improvement of at least one grade, and none showing decreased LLG. Increased LLG across all three treatment groups suggests that all methods increase meibum outflow to the tear film, resulting in a thicker lipid layer after treatment. These results suggest that all three treatments are effective in improving tear film quality, independent of MGD severity based either on symptoms or based on gland dropout. Copyright © 2017 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

  4. Study the Precipitation of Radiation Belt Electrons during the Rapid Dropout Events

    Science.gov (United States)

    Tu, W.; Cunningham, G.; Li, X.; Chen, Y.

    2015-12-01

    During the main phase of storms, the relativistic electron flux in the radiation belt can drop by orders of magnitude on timescales of a few hours. Where do the electrons go? This is one of the most important outstanding questions in radiation belt studies. Radiation belt electrons can be lost either by transport across the magnetopause into interplanetary space or by precipitation into the atmosphere. In this work we first conduct a survey of the MeV electron dropouts using the Van Allen Probes data in conjunction with the low-altitude measurements of precipitating electrons by 6 NOAA/POES satellites. The dropout events are categorized into three types: precipitation-loss dominant, outward radial diffusion dominant, or with contributions from both mechanisms. The survey results suggest the relative importance of precipitation and outward radial diffusion to the fast dropouts of radiation belt electrons, and their extent in L-shell and electron energy. Then, for specific events identified as dominated by precipitation loss, we use the Drift-Diffusion model, which includes the effects of azimuthal drift and pitch angle diffusion, to simulate both the electron dropout observed by Van Allen Probes and the distributions of drift-loss-cone electrons observed by multiple low-earth-orbit satellites (6 POES and the Colorado Student Space Weather Experiment). The model quantifies the electron precipitation loss and pitch angle diffusion coefficient, Dxx, with high temporal and spatial resolution. Finally, by comparing the Dxx derived from the model with those estimated from the quasi-linear theory using wave data from Van Allen Probes and other event-specific wave models, we are able to test the validity of quasi-linear theory and seek direct evidence of the wave-particle interactions during the dropouts.

  5. Relative age-related participation and dropout trends in German youth sports clubs.

    Science.gov (United States)

    Wattie, Nick; Tietjens, Maike; Cobley, Stephen; Schorer, Jörg; Baker, Joseph; Kurz, Dietrich

    2014-01-01

    Relative age describes a youth's age within their age group cohort. Compared to relatively younger peers, relatively older youth in an annual age group cohort have been found more likely to be selected to sports teams, and to receive higher grades in education. This study examined the influence of youth sport participants' relative age on participation and dropout. Using data from the 1995 German Youth Sport Survey (N total=2612), comparisons (stratified by gender and sport type) were made between the relative age of current and former participants. Analyses also considered the type of school youths were enrolled in while exploring the influence of relative age on sport participations. No relative age effects for dropout emerged among males in team or individual sport contexts. Female dropouts were more likely to be relatively older (Q1, OR adjusted: 0.52, 95% CI: 0.34-0.80; Q2, OR adjusted: 0.55, 95% CI: 0.36-0.84; Q3, OR adjusted: 0.59, 95% CI: 0.39-0.89), an effect that was mirrored among 'artistic' sport participants. Boys and girls in schools that were for children of higher academic proficiency were more likely to be currently participating in sport. Findings suggest that relative age-related dropout effects may be context sensitive and different for males and females. For the most part, relative age did not appear to have any relationship with dropout in this sample, with some notable exceptions for females. Overall, factors such as the type of school youths were enrolled in appear to be a more salient influence on sport participation than relative age.

  6. Mixed effects logistic regression models for longitudinal binary response data with informative drop-out.

    Science.gov (United States)

    Ten Have, T R; Kunselman, A R; Pulkstenis, E P; Landis, J R

    1998-03-01

    A shared parameter model with logistic link is presented for longitudinal binary response data to accommodate informative drop-out. The model consists of observed longitudinal and missing response components that share random effects parameters. To our knowledge, this is the first presentation of such a model for longitudinal binary response data. Comparisons are made to an approximate conditional logit model in terms of a clinical trial dataset and simulations. The naive mixed effects logit model that does not account for informative drop-out is also compared. The simulation-based differences among the models with respect to coverage of confidence intervals, bias, and mean squared error (MSE) depend on at least two factors: whether an effect is a between- or within-subject effect and the amount of between-subject variation as exhibited by variance components of the random effects distributions. When the shared parameter model holds, the approximate conditional model provides confidence intervals with good coverage for within-cluster factors but not for between-cluster factors. The converse is true for the naive model. Under a different drop-out mechanism, when the probability of drop-out is dependent only on the current unobserved observation, all three models behave similarly by providing between-subject confidence intervals with good coverage and comparable MSE and bias but poor within-subject confidence intervals, MSE, and bias. The naive model does more poorly with respect to the within-subject effects than do the shared parameter and approximate conditional models. The data analysis, which entails a comparison of two pain relievers and a placebo with respect to pain relief, conforms to the simulation results based on the shared parameter model but not on the simulation based on the outcome-driven drop-out process. This comparison between the data analysis and simulation results may provide evidence that the shared parameter model holds for the pain data.

  7. Revisiting the Link Between Depression Symptoms and High School Dropout: Timing of Exposure Matters.

    Science.gov (United States)

    Dupéré, Véronique; Dion, Eric; Nault-Brière, Frédéric; Archambault, Isabelle; Leventhal, Tama; Lesage, Alain

    2018-02-01

    Recent reviews concluded that past depression symptoms are not independently associated with high school dropout, a conclusion that could induce schools with high dropout rates and limited resources to consider depression screening, prevention, and treatment as low-priority. Even if past symptoms are not associated with dropout, however, it is possible that recent symptoms are. The goal of this study was to examine this hypothesis. In 12 disadvantaged high schools in Montreal (Canada), all students at least 14 years of age were first screened between 2012 and 2015 (N screened  = 6,773). Students who dropped out of school afterward (according to school records) were then invited for interviews about their mental health in the past year. Also interviewed were matched controls with similar risk profiles but who remained in school, along with average not at-risk schoolmates (N interviewed  = 545). Interviews were conducted by trained graduate students. Almost one dropout out of four had clinically significant depressive symptoms in the 3 months before leaving school. Adolescents with recent symptoms had an odd of dropping out more than twice as high as their peers without such symptoms (adjusted odds ratio = 2.17; 95% confidence interval = 1.14-4.12). In line with previous findings, adolescents who had recovered from earlier symptoms were not particularly at risk. These findings suggest that to improve disadvantaged youths' educational outcomes, investments in comprehensive mental health services are needed in schools struggling with high dropout rates, the very places where adolescents with unmet mental health needs tend to concentrate. Copyright © 2017 The Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  8. Couple Therapy with Veterans: Early Improvements and Predictors of Early Dropout.

    Science.gov (United States)

    Fischer, Melanie S; Bhatia, Vickie; Baddeley, Jenna L; Al-Jabari, Rawya; Libet, Julian

    2017-07-28

    Family services within Veterans Affairs Medical Centers fulfill an important role in addressing relationship distress among Veterans, which is highly prevalent and comorbid with psychopathology. However, even for evidence-based couple therapies, effectiveness is weaker compared to controlled studies, maybe because many Veteran couples drop out early and do not reach the "active" treatment stage after the 3-4 session assessment. In order to improve outcomes, it is critical to identify couples at high risk for early dropout, and understand whether couples may benefit from the assessment as an intervention. The current study examined (a) demographics, treatment delivery mode, relationship satisfaction, and psychological symptoms as predictors of dropout during and immediately following the assessment phase, and (b) changes in relationship satisfaction during assessment. 174 couples completed questionnaires during routine intake procedures. The main analyses focused on 140 male Veterans and their female civilian partners; 36.43% dropped out during the assessment phase and 24.74% of the remaining couples immediately following the first treatment session. More severe depressive symptoms in non-Veteran partners were associated with dropout during assessment. Relationship satisfaction improved significantly during the assessment phase for couples who did not drop out, with larger gains for non-Veteran partners. No demographics or treatment delivery mode were associated with dropout. Although more research is needed on engaging couples at risk for early dropout and maximizing early benefits, the findings suggest that clinicians should attend to the civilian partner's and Veteran's depressive symptoms at intake and consider the assessment part of active treatment. © 2017 Family Process Institute.

  9. Non-attendance and drop-out in cardiac rehabilitation among patients with ischaemic heart disease.

    Science.gov (United States)

    Mikkelsen, Tatsiana; Korsgaard Thomsen, Kristian; Tchijevitch, Olga

    2014-10-01

    Previous studies have shown drop-out from cardiac rehabilitation (CR) to have prognostic influence on morbidity and mortality among patients with ischaemic heart disease (IHD). We aimed to identify and clarify patients' reasons for non-attendance and drop-out from CR. A total of 872 consecutive patients with acute myocardial infarction and/or after percutaneous coronary intervention or coronary artery bypass surgery were asked by conventional mail to fill in a self-completion questionnaire on their choice of post-hospital CR and their reasons for drop-out or for non-attendance. Age, employment and marital status had a statistically significant influence on the overall course of CR. Younger age, affiliation with the labour market and living alone were related to a higher drop-out from CR in univariate analysis. We found no evidence of a gender difference among the patients who withdrew. Lack of time was stated as the prevailing reason for non-attendance and withdrawal from CR programmes among employed patients and in people aged 65 years or younger. Patients above 75 years of age asked for additional differentiation of exercise levels; currently two levels are offered. Or they found CR meaningless given their physical condition or their overall life situation. In patients with IHD, age, marital status and employment status play a role in the patient's attendance or drop out from CR. Different physical conditions, lack of time, too great a distance from residence to hospital, transport problems and lack of understanding of the benefits of CR explain why patients refuse to participate in or drop-out from CR. supported by grant from The Danish Ministry of Health. not relevant.

  10. Dropout rates in medical students at one school before and after the installation of admission tests in Austria.

    Science.gov (United States)

    Reibnegger, Gilbert; Caluba, Hans-Christian; Ithaler, Daniel; Manhal, Simone; Neges, Heide Maria; Smolle, Josef

    2011-08-01

    Admission to medical studies in Austria since academic year 2005-2006 has been regulated by admission tests. At the Medical University of Graz, an admission test focusing on secondary-school-level knowledge in natural sciences has been used for this purpose. The impact of this important change on dropout rates of female versus male students and older versus younger students is reported. All 2,860 students admitted to the human medicine diploma program at the Medical University of Graz from academic years 2002-2003 to 2008-2009 were included. Nonparametric and semiparametric survival analysis techniques were employed to compare cumulative probability of dropout between demographic groups. Cumulative probability of dropout was significantly reduced in students selected by active admission procedure versus those admitted openly (P dropout were higher for females (P dropout hazard is highest during the second year of study. The introduction of admission testing significantly decreased the cumulative probability for dropout. In openly admitted students a significantly higher risk for dropout was found in female students and in older students, whereas no such effects can be detected after admission testing. Future research should focus on the sex dependence, with the aim of improving success rates among female applicants on the admission tests.

  11. Are Barbie and Ken too cool for school? A case-control study on the relation between gender and dropout.

    Science.gov (United States)

    Theunissen, Marie-José; de Man, Inge; Verdonk, Petra; Bosma, Hans; Feron, Frans

    2015-02-01

    As school dropout is an important public health problem that needs to be addressed, we set out to examine whether and how, beyond the well-known effects of sex, gender beliefs and self-reported masculinity and femininity are related to school dropout. The study used a case-control design, consisting of 330 dropout cases and 330 controls still attending school. The respondents, aged between 18 and 23 years, living in the south-east of the Netherlands, were sent a self-administered questionnaire. Separate logistic regression analyses for the male and female participants were used to explore the relation between dropout and gender, controlling for sociodemographic determinants. As indicated by significant curvilinearity, young women were less likely to drop out when they occupied an intermediate positions on the gender variables. Odds of dropout were elevated among highly masculine women (odds ratio = 2.1, 95% confidence interval: 1.1-4.1), and, as indicated by significant interactions, also among highly masculine men with strong normative masculine beliefs and in feminine men who simultaneously considered themselves low on masculinity. Beyond sex, gender is important in the explanation of school dropout. To prevent dropout, public health professionals should assess, monitor and intervene on the basis of gender characteristics. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  12. Dropout from exercise randomized controlled trials among people with depression: A meta-analysis and meta regression.

    Science.gov (United States)

    Stubbs, Brendon; Vancampfort, Davy; Rosenbaum, Simon; Ward, Philip B; Richards, Justin; Soundy, Andrew; Veronese, Nicola; Solmi, Marco; Schuch, Felipe B

    2016-01-15

    Exercise has established efficacy in improving depressive symptoms. Dropouts from randomized controlled trials (RCT's) pose a threat to the validity of this evidence base, with dropout rates varying across studies. We conducted a systematic review and meta-analysis to investigate the prevalence and predictors of dropout rates among adults with depression participating in exercise RCT's. Three authors identified RCT's from a recent Cochrane review and conducted updated searches of major electronic databases from 01/2013 to 08/2015. We included RCT's of exercise interventions in people with depression (including major depressive disorder (MDD) and depressive symptoms) that reported dropout rates. A random effects meta-analysis and meta regression were conducted. Overall, 40 RCT's were included reporting dropout rates across 52 exercise interventions including 1720 people with depression (49.1 years (range=19-76 years), 72% female (range=0-100)). The trim and fill adjusted prevalence of dropout across all studies was 18.1% (95%CI=15.0-21.8%) and 17.2% (95%CI=13.5-21.7, N=31) in MDD only. In MDD participants, higher baseline depressive symptoms (β=0.0409, 95%CI=0.0809-0.0009, P=0.04) predicted greater dropout, whilst supervised interventions delivered by physiotherapists (β=-1.2029, 95%CI=-2.0967 to -0.3091, p=0.008) and exercise physiologists (β=-1.3396, 95%CI=-2.4478 to -0.2313, p=0.01) predicted lower dropout. A comparative meta-analysis (N=29) established dropout was lower in exercise than control conditions (OR=0.642, 95%CI=0.43-0.95, p=0.02). Exercise is well tolerated by people with depression and drop out in RCT's is lower than control conditions. Thus, exercise is a feasible treatment, in particular when delivered by healthcare professionals with specific training in exercise prescription. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Effect of child marriage on girls' school dropout in Nepal: Analysis of data from the Multiple Indicator Cluster Survey 2014

    Science.gov (United States)

    Sekine, Kazutaka; Hodgkin, Marian Ellen

    2017-01-01

    School dropout and child marriage are interrelated outcomes that have an enormous impact on adolescent girls. However, the literature reveals gaps in the empirical evidence on the link between child marriage and the dropout of girls from school. This study identifies the ‘tipping point’ school grades in Nepal when the risk of dropout due to marriage is highest, measures the effect of child marriage on girls’ school dropout rates, and assesses associated risk factors. Weighted percentages were calculated to examine the grades at highest risk and the distribution of reasons for discontinuing school. Using the Nepal Multiple Indicator Cluster Survey (MICS) 2014 data, we estimated the effect of marriage on school attendance and dropout among girls aged 15–17 by constructing logistic regression models. A multivariate logistic regression model was used to assess risk factors of school dropout due to child marriage. It was found that early marriage is the most common reason given for leaving school. Overall, the risk of school dropout due to marriage heightens after girls complete the fifth or sixth grade. The risk of girls’ dropping out peaks in the seventh and eighth grades and remains noteworthy in the ninth and tenth grades. Married girls in Nepal are 10 times more likely to drop out than their unmarried peers. Little or no education of the household head, belonging to the Kirat religion, and membership of a traditionally disadvantaged social class each elevate the risk of school dropout due to early marriage. The findings underscore the need to delay girl’s marriage so as to reduce girls’ school dropout in Nepal. School-based programmes aimed at preventing child marriage should target girls from the fifth grade because they are at increased risk of dropping out, as well as prioritizing girls from disadvantaged groups. PMID:28727793

  14. Effect of child marriage on girls' school dropout in Nepal: Analysis of data from the Multiple Indicator Cluster Survey 2014.

    Directory of Open Access Journals (Sweden)

    Kazutaka Sekine

    Full Text Available School dropout and child marriage are interrelated outcomes that have an enormous impact on adolescent girls. However, the literature reveals gaps in the empirical evidence on the link between child marriage and the dropout of girls from school. This study identifies the 'tipping point' school grades in Nepal when the risk of dropout due to marriage is highest, measures the effect of child marriage on girls' school dropout rates, and assesses associated risk factors. Weighted percentages were calculated to examine the grades at highest risk and the distribution of reasons for discontinuing school. Using the Nepal Multiple Indicator Cluster Survey (MICS 2014 data, we estimated the effect of marriage on school attendance and dropout among girls aged 15-17 by constructing logistic regression models. A multivariate logistic regression model was used to assess risk factors of school dropout due to child marriage. It was found that early marriage is the most common reason given for leaving school. Overall, the risk of school dropout due to marriage heightens after girls complete the fifth or sixth grade. The risk of girls' dropping out peaks in the seventh and eighth grades and remains noteworthy in the ninth and tenth grades. Married girls in Nepal are 10 times more likely to drop out than their unmarried peers. Little or no education of the household head, belonging to the Kirat religion, and membership of a traditionally disadvantaged social class each elevate the risk of school dropout due to early marriage. The findings underscore the need to delay girl's marriage so as to reduce girls' school dropout in Nepal. School-based programmes aimed at preventing child marriage should target girls from the fifth grade because they are at increased risk of dropping out, as well as prioritizing girls from disadvantaged groups.

  15. Effect of child marriage on girls' school dropout in Nepal: Analysis of data from the Multiple Indicator Cluster Survey 2014.

    Science.gov (United States)

    Sekine, Kazutaka; Hodgkin, Marian Ellen

    2017-01-01

    School dropout and child marriage are interrelated outcomes that have an enormous impact on adolescent girls. However, the literature reveals gaps in the empirical evidence on the link between child marriage and the dropout of girls from school. This study identifies the 'tipping point' school grades in Nepal when the risk of dropout due to marriage is highest, measures the effect of child marriage on girls' school dropout rates, and assesses associated risk factors. Weighted percentages were calculated to examine the grades at highest risk and the distribution of reasons for discontinuing school. Using the Nepal Multiple Indicator Cluster Survey (MICS) 2014 data, we estimated the effect of marriage on school attendance and dropout among girls aged 15-17 by constructing logistic regression models. A multivariate logistic regression model was used to assess risk factors of school dropout due to child marriage. It was found that early marriage is the most common reason given for leaving school. Overall, the risk of school dropout due to marriage heightens after girls complete the fifth or sixth grade. The risk of girls' dropping out peaks in the seventh and eighth grades and remains noteworthy in the ninth and tenth grades. Married girls in Nepal are 10 times more likely to drop out than their unmarried peers. Little or no education of the household head, belonging to the Kirat religion, and membership of a traditionally disadvantaged social class each elevate the risk of school dropout due to early marriage. The findings underscore the need to delay girl's marriage so as to reduce girls' school dropout in Nepal. School-based programmes aimed at preventing child marriage should target girls from the fifth grade because they are at increased risk of dropping out, as well as prioritizing girls from disadvantaged groups.

  16. Accommodating informative dropout and death: a joint modelling approach for longitudinal and semi-competing risks data.

    Science.gov (United States)

    Li, Qiuju; Su, Li

    2018-01-01

    Both dropout and death can truncate observation of a longitudinal outcome. Since extrapolation beyond death is often not appropriate, it is desirable to obtain the longitudinal outcome profile of a population given being alive. We propose a new likelihood-based approach to accommodating informative dropout and death by jointly modelling the longitudinal outcome and semi-competing event times of dropout and death, with an important feature that the conditional longitudinal profile of being alive can be conveniently obtained in a closed form. We use proposed methods to estimate different longitudinal profiles of CD4 count for patients from the HIV Epidemiology Research Study.

  17. Program specific admission testing and dropout for sports science students: a prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Lotte Dyhrberg O'Neill

    2014-09-01

    Full Text Available Recent research in medical education suggests that program specific admission testing could have a protective effect against early dropout. Little is known about the effect of program specific admission testing on dropout in other areas of higher education. The aim of this paper was to examine if admission strategy was also independently associated with dropout for sports science students in a university setting. The study design was a prospective cohort study with a 2 year follow-up. The population was 449 sports science students admitted to a university in the years 2002-2007. The analysis used was multivariate logistic regression and the predictors examined were: admission group (grade-based or admission tested as well as educational and socio-demographic variables. The outcome was dropout within 2 years of study start. Admission testing offered superior protection against dropout compared to grade-based admission. This result may fit with elements of previous dropout theory, student-environment fit theory and perhaps also with self-efficacy theory. Nyere forskning inden for medicinsk uddannelse indikerer at uddannelsesspecifikke optagelsesprøver kan have en beskyttende effekt i forhold til tidligt studiefrafald, men for andre universitetsuddannelser end Medicin synes denne sammenhæng endnu ikke at være blevet grundigt belyst. Formålet med dette studie var derfor at undersøge, om optagelsesprøver også beskyttede mod tidligt frafald blandt idrætsstuderende på universitetet. Studiedesignet var et prospektivt kohortestudie med to års opfølgning. Populationen var 449 idrætsstuderende, som blev optaget på Syddansk Universitet i årene 2002-2007. Data blev analyseret med multivariat logistisk regression, og følgende typer af prædiktorer for frafald blev undersøgt: Optagelseskvote (kvote 1 eller kvote 2 udprøvede, andre uddannelsesrelaterede variable samt udvalgte socio-demografiske variable. Effektmålet var studiestatus (frafaldet

  18. [Model of Engagement and Dropout for Adolescents with Borderline Personality Disorder].

    Science.gov (United States)

    Desrosiers, Lyne; Saint-Jean, Micheline; Laporte, Lise

    Objectives More than half of suicidal adolescents, a large proportion of which manifest borderline personality disorder (BPD), drop out from treatment. The consequences of their premature termination are cause for concern given the recurrence of their suicidal attempts and that they present elevated risk for major mental disorders during adulthood. The study sought to gain a broader appreciation of processes involved in the treatment dropout among adolescents with BPD.Method A constructivist grounded theory was chosen using a multiple-case research design. Twelve cases were examined. Three groups of informants were recruited (adolescents, parents, and therapists involved in the treatment) and 34 interviews were conducted to document the cases. Theoretical sampling and the different stages of analysis specific to grounded theory were performed according to the iterative process of constant comparative analysis.Results Various dropout vulnerabilities specific to adolescents with BPD and their parents, including psychological characteristics, help-seeking context and perception of mental illness and mental healthcare were identified. Care-setting response including management of accessibility problems, adaptation of services to needs of adolescents with BPD, preparation for treatment, and consideration for the health professional's disposition to treat were also found to be determinant to their engagement to treatment. The processes of disengagement from treatment have also been specified. Negative perceptions regarding treatment, clinicians and receiving treatment have been shown to generate emotional activation. The aforementioned lead to counterproductive attitudes that evolve into outright disengagement behaviours. In this context, responses from the care-setting, such as an insufficient regulation of the engagement, therapeutic faux pas and paradoxical demands, precipitate premature treatment termination. Finally, the processes involved in the abandonment of

  19. School Dropout and Associated Factors Among Omani Children with Attention-Deficit Hyperactivity Disorder: A Cross-Sectional Study.

    Science.gov (United States)

    Mirza, Hassan; Roberts, Emmert; Al-Belushi, Mohammed; Al-Salti, Humaid; Al-Hosni, Amira; Jeyaseelan, Lakshmanan; Al-Adawi, Samir

    Despite the rising incidence of attention-deficit hyperactivity disorder (ADHD), there is a dearth of studies examining the rate of school dropout and its correlates in non-Western populations. Medical records were scrutinized to identify Omani children diagnosed with ADHD from 2006 to 2014 in a tertiary care hospital in Oman. The persistence of ADHD symptoms, school performance and dropout, as well as sociodemographic characteristics were examined. Three hundred sixty-seven children fulfilled the diagnosis of ADHD based on Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) (DSM-IV) criteria and 16.6% of them had dropped out of school. School dropout was associated with poor school performance, comorbid conduct disorder, and parental divorce. This study from Oman concurs with existing literature that school dropout is common among children with ADHD. Concerted efforts are needed to mitigate this trend. Management strategies should incorporate the treatment of comorbid conduct disorder.

  20. Parent-child attachment, academic performance and the process of high-school dropout: a narrative review.

    Science.gov (United States)

    Ramsdal, Gro; Bergvik, Svein; Wynn, Rolf

    2015-01-01

    Poor academic performance is a strong predictor of school dropout. Researchers have tried to disentangle variables influencing academic performance. However, studies on preschool and early care variables are seldom examined when explaining the school dropout process. We reviewed the literature on the relationship between caregiver-child attachment and academic performance, including attachment studies from preschool years, seeking out potential contributions to academic performance and the dropout process. The review was organized according to a model of four main mediating hypotheses: the attachment-teaching hypothesis, the social network hypothesis, the attachment-cooperation hypothesis, and the attachment self-regulation hypothesis. The results of the review are summed up in a model. There is some support for all four hypotheses. The review indicates that attachment and early care contribute substantially to dropout and graduation processes. Mediation effects should be given far more attention in future research.

  1. Quantitative Susceptibility Mapping in Cerebral Cavernous Malformations: Clinical Correlations.

    Science.gov (United States)

    Tan, H; Zhang, L; Mikati, A G; Girard, R; Khanna, O; Fam, M D; Liu, T; Wang, Y; Edelman, R R; Christoforidis, G; Awad, I A

    2016-07-01

    Quantitative susceptibility mapping has been shown to assess iron content in cerebral cavernous malformations. In this study, our aim was to correlate lesional iron deposition assessed by quantitative susceptibility mapping with clinical and disease features in patients with cerebral cavernous malformations. Patients underwent routine clinical scans in addition to quantitative susceptibility mapping on 3T systems. Data from 105 patients met the inclusion criteria. Cerebral cavernous malformation lesions identified on susceptibility maps were cross-verified by T2-weighted images and differentiated on the basis of prior overt hemorrhage. Mean susceptibility per cerebral cavernous malformation lesion (χ̄lesion) was measured to correlate with lesion volume, age at scanning, and hemorrhagic history. Temporal rates of change in χ̄lesion were evaluated in 33 patients. Average χ̄lesion per patient was positively correlated with patient age at scanning (P cavernous malformation lesions with prior overt hemorrhages exhibited higher χ̄lesion than those without (P cavernous malformation lesions, higher mean quantitative susceptibility mapping signal in hemorrhagic lesions, and minimum longitudinal quantitative susceptibility mapping signal change in clinically stable lesions. Quantitative susceptibility mapping has the potential to be a novel imaging biomarker supplementing conventional imaging in cerebral cavernous malformations. The clinical significance of such measures merits further study. © 2016 by American Journal of Neuroradiology.

  2. Genetic susceptibility of periodontitis

    NARCIS (Netherlands)

    Laine, M.L.; Crielaard, W.; Loos, B.G.

    2012-01-01

    In this systematic review, we explore and summarize the peer-reviewed literature on putative genetic risk factors for susceptibility to aggressive and chronic periodontitis. A comprehensive literature search on the PubMed database was performed using the keywords ‘periodontitis’ or ‘periodontal

  3. Fourie susceptible.pmd

    African Journals Online (AJOL)

    Prof. Adipala Ekwamu

    a number of cultivars exhibited field resistance to halo blight and bacterial brown spot, all cultivars were more or less susceptible to .... Cerillos. Alubia. I. 91. 57. Kranskop. Red speckled sugar. II. 97. 63. OPS-RS1. Red speckled sugar. II. 96. 63. OPS-RS2. Red speckled sugar. I. 100. 61. OPS-RS3. Red speckled sugar. II. 97.

  4. Predictors of response and drop-out during intensive dialectical behavior therapy.

    Science.gov (United States)

    Perroud, Nader; Uher, Rudolf; Dieben, Karen; Nicastro, Rosetta; Huguelet, Philippe

    2010-10-01

    The purpose of this study was to examine the effectiveness, and predictors of response and drop-out during a four-week course of intensive dialectical behavior therapy (I-DBT) in 447 outpatients suffering from borderline personality disorder (BPD), over a 10-year period. Assessments included a diagnostic interview, the International Personality Disorder Examination Screening Questionnaire, the Beck Depression Inventory, and the Beck Hopelessness Scale. Among these participants, 103 started a second course of treatment. In agreement with previous reports, I-DBT was effective in reducing levels of depression and hopelessness with a trend of increasing effectiveness over the study period. High schizoid scores and low narcissistic score predicted poor response. Treatment completion rate was high, and low education predicted dropout. A discussion on the usefulness of a second course of treatment should be held with patients and staff as it was not effective in reducing depression and hopelessness.

  5. Dropout dynamics in pulsed quantum dot lasers due to mode jumping

    Energy Technology Data Exchange (ETDEWEB)

    Sokolovskii, G. S.; Dudelev, V. V.; Deryagin, A. G.; Novikov, I. I.; Maximov, M. V.; Ustinov, V. M.; Kuchinskii, V. I. [Ioffe Physical-Technical Institute, St. Petersburg (Russian Federation); Viktorov, E. A. [National Research University of Information Technologies, Mechanics and Optics, Saint Petersburg (Russian Federation); Optique Nonlinéaire Théorique, Campus Plaine CP 231, 1050 Bruxelles (Belgium); Applied Physics Research Group (APHY), Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels (Belgium); Abusaa, M. [Applied Physics Research Group (APHY), Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels (Belgium); Arab American University, Jenin, Palestine (Country Unknown); Danckaert, J. [Applied Physics Research Group (APHY), Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels (Belgium); Kolykhalova, E. D. [St. Petersburg State Electrotechnical University “LETI,” St. Petersburg (Russian Federation); Soboleva, K. K. [St. Petersburg State Polytechnical University, St. Petersburg (Russian Federation); Zhukov, A. E. [Academic University, St. Petersburg (Russian Federation); Sibbett, W. [University of St. Andrews, St. Andrews (United Kingdom); Rafailov, E. U. [Aston Institute of Photonic Technologies, Aston University, Birmingham (United Kingdom); Erneux, T. [Optique Nonlinéaire Théorique, Campus Plaine CP 231, 1050 Bruxelles (Belgium)

    2015-06-29

    We examine the response of a pulse pumped quantum dot laser both experimentally and numerically. As the maximum of the pump pulse comes closer to the excited-state threshold, the output pulse shape becomes unstable and leads to dropouts. We conjecture that these instabilities result from an increase of the linewidth enhancement factor α as the pump parameter comes close to the excitated state threshold. In order to analyze the dynamical mechanism of the dropout, we consider two cases for which the laser exhibits either a jump to a different single mode or a jump to fast intensity oscillations. The origin of these two instabilities is clarified by a combined analytical and numerical bifurcation diagram of the steady state intensity modes.

  6. H∞ Networked Cascade Control System Design for Turboshaft Engines with Random Packet Dropouts

    Directory of Open Access Journals (Sweden)

    Xiaofeng Liu

    2017-01-01

    Full Text Available The distributed control architecture becomes more and more important in future gas turbine engine control systems, in which the sensors and actuators will be connected to the controllers via a network. Therefore, the control problem of network-enabled high-performance distributed engine control (DEC has come to play an important role in modern gas turbine control systems, while, due to the properties of the network, the packet dropouts must be considered. This study introduces a distributed control system architecture based on a networked cascade control system (NCCS. Typical turboshaft engine distributed controllers are designed based on the NCCS framework with H∞ state feedback under random packet dropouts. The sufficient robust stable conditions are derived via the Lyapunov stability theory and linear matrix inequality approach. Simulations illustrate the effectiveness of the presented method.

  7. Outer Radiation Belt Dropout Dynamics Following the Arrival of Two Interplanetary Coronal Mass Ejections

    Science.gov (United States)

    Alves, L. R.; Da Silva, L. A.; Souza, V. M.; Sibeck, D. G.; Jauer, P. R.; Vieira, L. E. A.; Walsh, B. M.; Silveira, M. V. D.; Marchezi, J. P.; Rockenbach, M.; hide

    2016-01-01

    Magnetopause shadowing and wave-particle interactions are recognized as the two primary mechanisms for losses of electrons from the outer radiation belt. We investigate these mechanisms, sing satellite observations both in interplanetary space and within the magnetosphere and particle drift modeling. Two interplanetary shocks sheaths impinged upon the magnetopause causing a relativistic electron flux dropout. The magnetic cloud (C) and interplanetary structure sunward of the MC had primarily northward magnetic field, perhaps leading to a concomitant lack of substorm activity and a 10 day long quiescent period. The arrival of two shocks caused an unusual electron flux dropout. Test-particle simulations have shown 2 to 5 MeV energy, equatorially mirroring electrons with initial values of L 5.5can be lost to the magnetosheath via magnetopause shadowing alone. For electron losses at lower L-shells, coherent chorus wave-driven pitch angle scattering and ULF wave-driven radial transport have been shownto be viable mechanisms.

  8. Is ADHD a Risk Factor for High School Dropout? A Controlled Study.

    Science.gov (United States)

    Fried, Ronna; Petty, Carter; Faraone, Stephen V; Hyder, Laran L; Day, Helen; Biederman, Joseph

    2016-05-01

    This study examined whether ADHD was an independent contributor to grade retention when adjusting for IQ, learning disorders, and social class. Outcome data was from participants in studies at Massachusetts General Hospital (n= 404 ADHD,n= 349 controls) who underwent psychiatric interviews, socioeconomic status measures, and IQ testing. 28% of individuals with ADHD repeated a grade compared with 7% of controls (pschool dropout or repeated grade. An interaction effect of ADHD and gender was also found with females with ADHD having a higher risk ratio for repeated grade/dropout compared with males with ADHD. Participants with ADHD were significantly more likely to repeat a grade, adjusting for all other variables indicating the critical importance of early identification of ADHD to help mitigate adverse educational outcomes. © The Author(s) 2013.

  9. How can we strengthen students’ social relations in order to reduce school dropout?

    DEFF Research Database (Denmark)

    Ingholt, Liselotte; Sørensen, Betina Bang; Andersen, Susan

    2015-01-01

    was performed to investigate the specific relationships between the social environment within the schools and the institutional structures in order to analyse reasons for school dropout and their relation to well-being, cigarette smoking and substance use. METHODS: The development study was based......BACKGROUND: This article describes the rationale and contents of an intervention program aimed at strengthening students' social relations in order to reduce dropout from vocational schools in Denmark. Taking its theoretical cue from the concept of 'social participation', a qualitative study...... additional qualitative interviews and four group interviews were conducted with students 16-25 years old. RESULTS: The qualitative data collection resulted in seven major themes to be addressed in the intervention: social relations, sole focus on professional skills, institutionalized individualization...

  10. Factors associated with non-participation and dropout among cancer patients in a cluster-randomised controlled trial.

    Science.gov (United States)

    Roick, J; Danker, H; Kersting, A; Briest, S; Dietrich, A; Dietz, A; Einenkel, J; Papsdorf, K; Lordick, F; Meixensberger, J; Mössner, J; Niederwieser, D; Prietzel, T; Schiefke, F; Stolzenburg, J-U; Wirtz, H; Singer, S

    2018-01-01

    We investigated the impact of demographic and disease related factors on non-participation and dropout in a cluster-randomised behavioural trial in cancer patients with measurements taken between hospitalisation and 6 months thereafter. The percentages of non-participation and dropout were documented at each time point. Factors considered to be potentially related with non-participation and dropout were as follows: age, sex, marital status, education, income, employment status, tumour site and stage of disease. Of 1,338 eligible patients, 24% declined participation at baseline. Non-participation was higher in older patients (Odds Ratio [OR] 2.1, CI: 0.6-0.9) and those with advanced disease (OR 2.0, CI: 0.1-1.3). Dropout by 6 months was 25%. Dropout was more frequent with increased age (OR 2.8, CI: 0.8-1.2), advanced disease (OR 3.0, CI: 1.0-1.2), being married (OR 2.4, CI 0.7-1.1) and less frequent with university education (OR 0.4, CI -1.3 to -0.8) and middle income (OR 0.4, CI -0.9 to -0.7). When planning clinical trials, it is important to be aware of patient groups at high risk of non-participation or dropout, for example older patients or those with advanced disease. Trial designs should consider their special needs to increase their rate of participation. © 2017 John Wiley & Sons Ltd.

  11. Predictors of Dropout by Female Obese Patients Treated with a Group Cognitive Behavioral Therapy to Promote Weight Loss

    Directory of Open Access Journals (Sweden)

    Ryoko Sawamoto

    2016-01-01

    Full Text Available Objective: To investigate predictors of dropout from a group cognitive behavioral therapy (CBT intervention for overweight or obese women. Methods: 119 overweight and obese Japanese women aged 25-65 years who attended an outpatient weight loss intervention were followed throughout the 7-month weight loss phase. Somatic characteristics, socioeconomic status, obesity-related diseases, diet and exercise habits, and psychological variables (depression, anxiety, self-esteem, alexithymia, parenting style, perfectionism, and eating attitude were assessed at baseline. Significant variables, extracted by univariate statistical analysis, were then used as independent variables in a stepwise multiple logistic regression analysis with dropout as the dependent variable. Results: 90 participants completed the weight loss phase, giving a dropout rate of 24.4%. The multiple logistic regression analysis demonstrated that compared to completers the dropouts had significantly stronger body shape concern, tended to not have jobs, perceived their mothers to be less caring, and were more disorganized in temperament. Of all these factors, the best predictor of dropout was shape concern. Conclusion: Shape concern, job condition, parenting care, and organization predicted dropout from the group CBT weight loss intervention for overweight or obese Japanese women.

  12. Predictors of Dropout by Female Obese Patients Treated with a Group Cognitive Behavioral Therapy to Promote Weight Loss.

    Science.gov (United States)

    Sawamoto, Ryoko; Nozaki, Takehiro; Furukawa, Tomokazu; Tanahashi, Tokusei; Morita, Chihiro; Hata, Tomokazu; Komaki, Gen; Sudo, Nobuyuki

    2016-01-01

    To investigate predictors of dropout from a group cognitive behavioral therapy (CBT) intervention for overweight or obese women. 119 overweight and obese Japanese women aged 25-65 years who attended an outpatient weight loss intervention were followed throughout the 7-month weight loss phase. Somatic characteristics, socioeconomic status, obesity-related diseases, diet and exercise habits, and psychological variables (depression, anxiety, self-esteem, alexithymia, parenting style, perfectionism, and eating attitude) were assessed at baseline. Significant variables, extracted by univariate statistical analysis, were then used as independent variables in a stepwise multiple logistic regression analysis with dropout as the dependent variable. 90 participants completed the weight loss phase, giving a dropout rate of 24.4%. The multiple logistic regression analysis demonstrated that compared to completers the dropouts had significantly stronger body shape concern, tended to not have jobs, perceived their mothers to be less caring, and were more disorganized in temperament. Of all these factors, the best predictor of dropout was shape concern. Shape concern, job condition, parenting care, and organization predicted dropout from the group CBT weight loss intervention for overweight or obese Japanese women. © 2016 S. Karger GmbH, Freiburg.

  13. School disengagement as a predictor of dropout, delinquency, and problem substance use during adolescence and early adulthood.

    Science.gov (United States)

    Henry, Kimberly L; Knight, Kelly E; Thornberry, Terence P

    2012-02-01

    Over the past 5 years, a great deal of attention has been paid to the development of early warning systems for dropout prevention. These warning systems use a set of indicators based on official school records to identify youth at risk for dropout and then appropriately target intervention. The current study builds on this work by assessing the extent to which a school disengagement warning index predicts not only dropout but also other problem behaviors during middle adolescence, late adolescence, and early adulthood. Data from the Rochester Youth Development Study (N = 911, 73% male, 68% African American, and 17% Latino) were used to examine the effects of a school disengagement warning index based on official 8th and 9th grade school records on subsequent dropout, as well as serious delinquency, official offending, and problem substance use during middle adolescence, late adolescence, and early adulthood. Results indicate that the school disengagement warning index is robustly related to dropout as well as serious problem behaviors across the three developmental stages, even after controlling for important potential confounders. High school dropout mediates the effect of the warning index on serious problem behaviors in early adulthood.

  14. Modeling dropout from adverse event data: impact of dosing regimens across pregabalin trials in the treatment of generalized anxiety disorder.

    Science.gov (United States)

    Lalovic, Bojan; Hutmacher, Matt; Frame, Bill; Miller, Raymond

    2011-05-01

    Dizziness represents a major determinant of dropout in the treatment of generalized anxiety disorder with pregabalin. Titration (dose escalation) regimens based on clinical judgment were implemented to mitigate this adverse event and reduce patient dropout across clinical trials. Dropout is an important treatment failure endpoint, which can be analyzed using time-to-event models that incorporate daily dosing or other time-varying information. A parametric discrete-time dropout model with daily dizziness severity score as a covariate afforded a systematic, model-based assessment of titration dosing strategies, with model predictions evaluated against corresponding nonparametric estimates. A Gompertz hazard function adequately described the decreasing dropout hazard over time for individuals with severe or moderate dizziness and a lower, constant hazard for individuals reporting no dizziness or mild dizziness. Predictive performance of the model was adequate based on external validation with an independent trial and other goodness-of-fit criteria. Prospective simulations highlight the utility of this approach in reducing dropout based on examination of untested titration scenarios for future generalized anxiety disorder or other trials.

  15. A SURVEY ON STUDENT\\'S OPINION ABOUT EFFECTIVE FACTORS FOR ACADEMIC DROPOUT IN SHAHID SADOUGHI UNIVERSITY

    Directory of Open Access Journals (Sweden)

    T Salimi

    2007-07-01

    Full Text Available Introduction: University's students are faced with a lot of problems such as dropout. There are many factors to happen and by destroyed. Aim of this study was to determine the student's opinions about most effective factors for academic dropout in Shahid Sadoughi University. Methods: This is a descriptive – analytic study. In total 40 students who had dropped out and 60 students who had not dropout, in their academic curriculum, were enrolled in the study. A questionnaire contains questions related to the demographic & effective features, which completed by each student. Results: There was a significant difference between two groups for age, marriage status, condition level at the entry time (p=0.000 from statically point of view in the age , The marriage status , quota ( p=0.000 , who the students live with ( p=0.004 ,and crisis in family ( p=0.04 . The students that dropout were often older, married, with specific quota, live with roommates, and with crisis in family. These students were often boys and dropped out in special courses. The opinions of dropped out students about the importance effective factors for academic dropout were faraway from family, lack of program, be employed, inappropriate questions of examinations, shortage of time examinations, diseases, and less motivation. Conclusion: According to the results of this study and other related studies, it is recommended that the heads of educational units increase their attention to importance effective factors for academic dropout, including married students with specific quota and the roommates situation.

  16. Psychosocial risk and protective factors of secondary school dropout in Luxembourg: the protocol of an exploratory case-control study

    Directory of Open Access Journals (Sweden)

    Lair Marie-Lise

    2011-07-01

    Full Text Available Abstract Background In Luxembourg, the extensive phenomenon of school dropout is a prime policy concern in the light of individual, social and economic consequences. Although the authorities report an overall decrease of the national dropout rate, the proportion of early school leavers who remain without any specific occupation is still alarming. Therefore, this study intends a shift of focus from system-inherent to individual factors, including mental health and family correlates, to provide a more comprehensive analysis of the dropout phenomenon. Methods/Design The objectives of this study are to investigate the type and prevalence of psychiatric disorders among school dropouts and to compare the findings with those by a matched control group of regularly enrolled students. Furthermore, family variables and socioeconomic status will be analysed, as they are factors likely to interfere with both educational attainment and mental health. A trained psychologist will use structured interviews and self-report forms to investigate for mental health issues, information on schooling, socioeconomic situation and family life. Controls will be matched for gender, age, school type and educational grade. Discussion As school dropouts face a serious risk of long term professional and social marginalization, there is an evident need for action. Identifying psychosocial risk and protective factors of school dropout will deliver solid insight on how to conceive public health strategies for young people who may need a more customized support to carry out their academic potential. Trial registration ClinicalTrials.gov Identifier: NCT01354236

  17. Quantifying the effect of magnetopause shadowing on electron radiation belt dropouts

    Directory of Open Access Journals (Sweden)

    Y. Yu

    2013-11-01

    Full Text Available Energetic radiation belt electron fluxes can undergo sudden dropouts in response to different solar wind drivers. Many physical processes contribute to the electron flux dropout, but their respective roles in the net electron depletion remain a fundamental puzzle. Some previous studies have qualitatively examined the importance of magnetopause shadowing in the sudden dropouts either from observations or from simulations. While it is difficult to directly measure the electron flux loss into the solar wind, radial diffusion codes with a fixed boundary location (commonly utilized in the literature are not able to explicitly account for magnetopause shadowing. The exact percentage of its contribution has therefore not yet been resolved. To overcome these limitations and to determine the exact contribution in percentage, we carry out radial diffusion simulations with the magnetopause shadowing effect explicitly accounted for during a superposed solar wind stream interface passage, and quantify the relative contribution of the magnetopause shadowing coupled with outward radial diffusion by comparing with GPS-observed total flux dropout. Results indicate that during high-speed solar wind stream events, which are typically preceded by enhanced dynamic pressure and hence a compressed magnetosphere, magnetopause shadowing coupled with the outward radial diffusion can explain about 60–99% of the main-phase radiation belt electron depletion near the geosynchronous orbit. While the outer region (L* > 5 can nearly be explained by the above coupled mechanism, additional loss mechanisms are needed to fully explain the energetic electron loss for the inner region (L* ≤ 5. While this conclusion confirms earlier studies, our quantification study demonstrates its relative importance with respect to other mechanisms at different locations.

  18. Early school dropouts in developing countries: An integer approach to guide intervention. The case of Uruguay

    OpenAIRE

    Rossana Patrón

    2008-01-01

    Are early leavers from the education system irrational or ill informed? They might be, but this approach shows that with underperforming education sectors – typical in developing countries – early dropout may be perfectly rational and well informed, even in the absence of liquidity constraints. This paper provides an integer approach to guide intervention in developing countries, though there are no clear-cut policies. Long-term measures should be aimed at improving the productivity of the ac...

  19. Programs and policies to assist high school dropouts in the transition to adulthood.

    Science.gov (United States)

    Bloom, Dan

    2010-01-01

    Dan Bloom of MDRC examines policies and programs designed to help high school dropouts improve their educational attainment and labor market outcomes. So called "second-chance" programs, he says, have long provided some combination of education, training, employment, counseling, and social services. But the research record on their effectiveness is fairly thin, he says, and the results are mixed. Bloom describes eleven employment- or education-focused programs serving high school dropouts that have been rigorously evaluated over the past thirty years. Some relied heavily on paid work experience, while others focused more on job training or education. Some programs, especially those that offered paid work opportunities, generated significant increases in employment or earnings in the short term, but none of the studies that followed participants for more than a couple of years found lasting improvements in economic outcomes. Nevertheless, the findings provide an important foundation on which to build. Because of the high individual and social costs of ignoring high school dropouts, the argument for investing more public funds in services, systems, and research for these young people is strong. The paucity of conclusive evidence, however, makes it hard to know how to direct resources and magnifies the importance of ensuring that all new initiatives provide for rigorous evaluation of their impacts. Bloom concludes with recommendations for policy and research aimed at building on current efforts to expand and improve effective programs for dropouts while simultaneously developing and testing new approaches that might be more effective and strengthening local systems to support vulnerable young people. He stresses the importance of identifying and disseminating strategies to engage young people who are more seriously disconnected and unlikely to join programs. A recurring theme is that providing young people with opportunities for paid work may be useful both as an

  20. Impact of Dupoto-e-Maa education project on dropout rate and academic performance

    Directory of Open Access Journals (Sweden)

    James B. Ouda

    2016-09-01

    Conclusion: The study recommended that there is need to increase the number of non-governmental organisations modelled around the Dupoto-e-Maa education project so as to reduce dropout rate and improve pupil academic performance. The findings could also inform government policy in terms of recruitment and placement of teachers in schools in arid and semi-arid lands. Project funding could be increased to improve visibility and sustainability of project activities.

  1. Shooting for the Stars and Failing: College Dropout and Self-Esteem

    OpenAIRE

    Peter Hoeschler; Uschi Backes-Gellner

    2014-01-01

    We investigate the relationship between unfulfilled educational aspirations and self-esteem. Classifications of education relying on completed years of schooling or degree attainment are not able to distinguish between college dropouts with unfulfilled aspirations and graduates with fulfilled aspirations. To separate the two groups, we develop a classification of education combining the highest type of college enrolled in (aspiration) and the highest degree obtained (realization of aspiration...

  2. Why Tenth Graders Fail to Finish High School: A Dropout Typology Latent Class Analysis

    Science.gov (United States)

    Bowers, Alex J.; Sprott, Ryan

    2012-01-01

    A large percentage of the students who drop out of K-12 schools in the United States do so at the end of high school, at some point after grade 10. Yet little is known about the differences between types of students who drop out near the end of high school. The purpose of this study is to examine a typology of high school dropouts from a large…

  3. The impact of drop-out in cardiac rehabilitation on outcome among coronary artery disease patients.

    Science.gov (United States)

    Pardaens, Sofie; Willems, Anne-Marie; Clays, Els; Baert, Anneleen; Vanderheyden, Marc; Verstreken, Sofie; Du Bois, Inge; Vervloet, Delphine; De Sutter, Johan

    2017-09-01

    Background The effect of adherence to cardiac rehabilitation (CR) on outcome is not clear. Therefore, we aimed to assess the impact of drop-out for non-medical reasons of CR on event-free survival in coronary artery disease (CAD). Methods A total of 876 patients who attended CR after acute coronary syndrome (ACS), percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) were included. Drop-out was defined as attending ≤50% of the training sessions. A combined endpoint of all-cause mortality and rehospitalization for a cardiovascular event was used to specify event-free survival. Differences in clinical characteristics were assessed and parameters with p dropped out before finishing half of the program. Patients who withdrew prematurely had a risk twice as high for a cardiovascular event or death (hazard ratio 1.92, 95% confidence interval 1.28-2.90) than those who attended more than half of the sessions. Both ACS (2.36, 1.47-3.58) and PCI (2.20, 1.22-3.96), as primary indicators for CR, were associated with an adverse outcome and also a prior history of chronic heart failure (CHF) remained negatively associated with event-free survival (3.67, 1.24-10.91). Finally, the presence of hyperlipidemia was independently related to a worse outcome (1.48, 1.02-2.16). Conclusions Drop-out for non-medical reasons was independently associated with a negative outcome in CAD. Therefore, underlying factors for drop-out should gain more attention in future research and should be taken into account when organizing CR.

  4. Gamblers' habits: empirical evidence on the behavior of regulars, newcomers and dropouts.

    Science.gov (United States)

    Fiedler, Ingo

    2013-06-01

    Electronic gambling offers the opportunity to analyze huge and unbiased data sets of automatically recorded actual gambling behavior. This study refers to data on 2,127,887 poker playing identities from the Online Poker Database of the University of Hamburg (OPD-UHH) to analyze three subgroups of gamblers: regulars, newcomers, and dropouts. Their gambling habits over 6 months are analyzed in total, as well as over time. Regulars show a much higher involvement than non-regulars and increase their playing volume slightly over the observation period. Newcomers have a lower involvement than non-newcomers and most of them decrease their playing volume over time. Still, there is a small group of newcomers which increases their playing volume sharply and is, hence, very interesting for the industry as well as for the early prevention of pathological gambling. Dropouts have a higher gambling involvement than newcomers but play less than players who have not stopped stop gambling. Most dropouts also show a decreasing playing volume before dropping out. An analysis of the correlations between different variables of gambling habits shows that most of them reinforce each other, for example: gamblers with a higher total playing time tend to play at more tables simultaneously. Only playing frequency is a moderating variable of gambling involvement.

  5. Sudden declines in intelligence in old age predict death and dropout from longitudinal studies.

    Science.gov (United States)

    Rabbitt, Patrick; Lunn, Mary; Wong, Danny; Cobain, Mark

    2008-07-01

    It is well known that approaching death accelerates cognitive decline. The converse issue, that is, the question of whether rapid declines in cognitive ability are risk factors for imminent death, has not been investigated. Every 4 years between 1983 and 2003, we gave 1,414 healthy community residents who were aged between 49 and 93 years the Heim AH4-1 test of fluid intelligence. A modified Andersen-Gill model evaluated AH4-1 scores at entry to the study and changes in scores between successive quadrennial test sessions as risk factors for death and dropout. Deaths, dropouts, age, gender, occupational categories, and recruitment cohorts were also taken into account. Participants with lower AH4-1 scores on entry were significantly more likely to die or to drop out. At all ages and levels of baseline intelligence, the risks of deaths and dropouts further increased if test scores fell by 10%, and again increased if they fell by 20% during 4-year intervals between successive assessments.

  6. Personality dimensions and treatment drop-outs among eating disorder patients treated with cognitive behavior therapy.

    Science.gov (United States)

    Dalle Grave, Riccardo; Calugi, Simona; Brambilla, Francesca; Marchesini, Giulio

    2008-04-15

    Premature, unilateral interruption of inpatient treatment of eating disorders (ED) is a key factor limiting success. We evaluated the role of personality dimensions (temperament and character) in predicting drop-out in 145 consecutive ED inpatients (133 females) who entered cognitive behavior therapy. Baseline assessment included anthropometry, the Eating Disorder Examination, the Beck Depression Inventory, the State-Trait Anxiety Inventory, and the Temperament and Character Inventory (TCI). Treatment was based on the new transdiagnostic cognitive behavior theory of ED, adapted for an inpatient setting; it was manual-based and lasted 20 weeks (13, inpatients; 7, residential day hospital). Thirty-four patients (23.4%) discontinued treatment. Drop-outs had a lower level of education, a higher prevalence of separation or divorce in the family, and lower scores on the TCI Persistence scale. After correction for age, gender and body-mass index, scores on the Persistence scale continued to be significantly related to drop-out, and the association was confirmed by Kaplan-Meier analysis. Eating disorder patients with low Persistence scores are significantly less likely to complete inpatient treatment.

  7. Understanding the Mechanisms of Radiation Belt Dropouts Observed by Van Allen Probes

    Science.gov (United States)

    Xiang, Zheng; Tu, Weichao; Li, Xinlin; Ni, Binbin; Morley, S. K.; Baker, D. N.

    2017-10-01

    To achieve a better understanding of the dominant loss mechanisms for the rapid dropouts of radiation belt electrons, three distinct radiation belt dropout events observed by Van Allen Probes are comprehensively investigated. For each event, observations of the pitch angle distribution of electron fluxes and electromagnetic ion cyclotron (EMIC) waves are analyzed to determine the effects of atmospheric precipitation loss due to pitch angle scattering induced by EMIC waves. Last closed drift shells (LCDS) and magnetopause standoff position are obtained to evaluate the effects of magnetopause shadowing loss. Evolution of electron phase space density (PSD) versus L* profiles and the μ and K (first and second adiabatic invariants) dependence of the electron PSD drops are calculated to further analyze the dominant loss mechanisms at different L*. Our findings suggest that these radiation belt dropouts can be classified into distinct classes in terms of dominant loss mechanisms: magnetopause shadowing dominant, EMIC wave scattering dominant, and combination of both mechanisms. Different from previous understanding, our results show that magnetopause shadowing can deplete electrons at L* 4. Compared to the magnetopause standoff position, it is more reliable to use LCDS to evaluate the impact of magnetopause shadowing. The evolution of electron PSD versus L* profile and the μ, K dependence of electron PSD drops can provide critical and credible clues regarding the mechanisms responsible for electron losses at different L* over the outer radiation belt.

  8. El problema del abandono de los estudios universitarios. [The dropout problem in university study

    Directory of Open Access Journals (Sweden)

    Lidia Cabrera

    2006-07-01

    Full Text Available This article focuses on the dropout of university students, which in some cases can be as high as 50%. This study presents and analyses the dropout rates that are found in several Spanish universities. Using the results of national and international studies as background and the findings from our own investigation, we present a theoretical framework that identifies the definition of dropouts, the causes, the explanatory models and solutions used to understand this issue. The article concludes by presenting a critical perspective of university learning in relation to the social role that universities represent, and addresses the actual processes of change, particularly in light of the European convergence. En este artículo se analiza el fenómeno problemático del abandono de los estudios universitarios, que alcanza hasta el 50% en algunas titulaciones. Para ello, partimos de la presentación y análisis de los porcentajes de abandono de distintas universidades españolas. Posteriormente, al amparo de distintos estudios nacionales e internacionales, y nuestros resultados de investigación, elaboramos un perfil teórico que contempla: definición, causas, modelos explicativos y soluciones. Finalmente, ofrecemos una perspectiva crítica de la enseñanza universitaria, en relación al papel social que esta representa, y en relación a los actuales procesos de cambio, sobre todo el proceso de convergencia europea.

  9. Predictors of Relapse and Dropout During a 12-Week Relapse Prevention Program for Methamphetamine Users.

    Science.gov (United States)

    Chen, Yi-Chih; Chen, Chih-Ken; Wang, Liang-Jen

    2015-01-01

    In this research, the possible neuropsychological predictors of relapse and dropout of group cognitive behavioral therapy (CBT) for methamphetamine (MA) users were explored. Participants were 42 MA users sentenced by the judicial system to take part in an out-patient relapse prevention program for MA abuse and dependence that employs a CBT model once a week over the course of 12 weeks. Baseline neuropsychological functions were evaluated with the Conners' Continuous Performance Test, Wisconsin Card Sorting Test, Iowa Gambling Task, and Barratt Impulsiveness Scale. All participants had to submit to urine drug tests every week. Of the 42 participants, 69.0% had a MA positive urine screening result at least once throughout the program (relapse), while 40.5% dropped out of the treatment program prior to its completion. Short duration of MA abstinence at baseline and poor attention predicted relapse. Predictors of dropout included being unmarried and having risky decision making. Findings may be helpful for clinicians, who can screen for the aforementioned risk factors and provide strategies for high-risk patients to help prevent relapse and dropout among MA users in treatment programs.

  10. Genetic Susceptibility to Atherosclerosis

    Directory of Open Access Journals (Sweden)

    Sanja Kovacic

    2012-01-01

    Full Text Available Atherosclerosis is a complex multifocal arterial disease involving interactions of multiple genetic and environmental factors. Advances in techniques of molecular genetics have revealed that genetic ground significantly influences susceptibility to atherosclerotic vascular diseases. Besides further investigations of monogenetic diseases, candidate genes, genetic polymorphisms, and susceptibility loci associated with atherosclerotic diseases have been identified in recent years, and their number is rapidly increasing. This paper discusses main genetic investigations fields associated with human atherosclerotic vascular diseases. The paper concludes with a discussion of the directions and implications of future genetic research in arteriosclerosis with an emphasis on prospective prediction from an early age of individuals who are predisposed to develop premature atherosclerosis as well as to facilitate the discovery of novel drug targets.

  11. Obesity treatment in elderly outpatients: predictors of efficacy and drop-out.

    Science.gov (United States)

    Busetto, L; Mazza, M; Salvalaio, S; De Stefano, F; Marangon, M; Calò, E; Sampietro, S; Enzi, G

    2009-01-01

    Obesity is increasing in the elderly and it is associated with an increased risk of medical complications, decline in physical function and disability. Very few studies specifically evaluated the outcome of obesity treatment in the aging patients. Aim of this work is therefore the evaluation of the efficacy of medical therapy in a group of obese patients >or=65 years old. The study has been performed on the clinical records of obese outpatients treated at the medical branch of the Unit for Medical and Surgical Therapy of Obesity at the University of Padova. Patients were recruited from January 1st, 2001 to June 30th, 2006 in order to have patients with at least one year of potential follow-up. In particular two groups were enrolled: 100 patients >or=65 years old and 200 patients treatment outcome were compared. Mean age of the elderly patients was 69.1+/-3.7 years (range 65-80 years). We did not find any significant difference between elderly and adult patients in the sex distribution (female patients 76% in the elderly group and 72% in the adult group; p=0.276) and in the severity of overweight (body mass index: 37.8+/-6.0 kg/m2 in the elderly; 37.2+/-6.3 kg/m2 in adults; p=0.425). The elderly group was characterized by a higher incidence of comorbidities and a lower incidence of eating behavior disorders at baseline. No significant differences in the dietary prescription were found, whereas physical activity was prescribed in 27/100 elderly patients (27%) and in 97/200 (48%) adults patients (ptreatment. In elderly patients still in active treatment after 12 months, only 5/28 (18%) patients reached the specified goal, whereas in adult patients still in treatment, 18/47 (38%) patients reached the goal (page at baseline, female sex, and lower body mass index were found to be the only significant predictors of 10% weight loss in logistic regression. In our experience, drop-out rate after 12 months was similar in adults (77%) and in older patients (72%). In a

  12. Marijuana Usage and Hypnotic Susceptibility

    Science.gov (United States)

    Franzini, Louis R.; McDonald, Roy D.

    1973-01-01

    Anonymous self-reported drug usage data and hypnotic susceptibility scores were obtained from 282 college students. Frequent marijuana users (more than 10 times) showed greater susceptibility to hypnosis than nonusers. (Author)

  13. Factors associated with non-participation and drop-out in a lifestyle intervention for workers with an elevated risk of cardiovascular disease

    OpenAIRE

    Groeneveld, I.F.; Proper, K.I.; Beek, A.J. van der; Hildebrandt, V.H.; Mechelen, W. van

    2009-01-01

    Abstract Background Non-response and drop-out are problems that are commonly encountered in health promotion trials. Understanding the health-related characteristics of non-participants and drop-outs and the reasons for non-participation and drop-out may be beneficial for future intervention trials. Methods Male construction workers with an elevated risk of cardiovascular disease (CVD) were invited to participate in a lifestyle intervention study. In order to investigate the associations betw...

  14. Social quotas, affirmative actions, and dropout in the Business field: empirical analysis in a Brazilian federal university

    Directory of Open Access Journals (Sweden)

    Larissa Couto Campos

    Full Text Available ABSTRACT Rawls' Justice Theory establishes that a fair society must allow less advantaged people to have access to the benefits of social cooperation. In this line of thought, the affirmative actions established by Law 12,711/2012 aim at promoting inclusive education in Higher Education. Evaluating the performance of affirmative actions, specifically their impact on the dropout level, has been a theme of debate in scientific literature. Besides representing a personal frustration, dropout is associated with significant academic, social, and economic losses. In this context, this research aims at analyzing whether the adoption of affirmative actions, as established by Law 12,711/2012, affects the dropout rates of students in Accounting Sciences and other courses in the Business field. The study was conducted through documentary research in a Brazilian public Higher Education institution (HEI. The results of binomial analysis showed that out of the 2,418 students who entered in the first semester of 2013, 520 (22% dropped out from university until the end of the first semester of 2014. It was found that the dropout rate among entrants in the Business field, either through broad competition or using the system of quotas, was 29%. In the course of Accounting Sciences, the dropout rate among entrants admitted through broad competition was 25% and using the system of quotas it was 23%. Contrary to other investigations, this study found that there is no statistical difference between the dropout rates among entrants in the Business and Accounting Sciences fields through broad competition and quotas, suggesting that affirmative actions do not affect significantly the dropout rates.

  15. An alternative parameterization of the general linear mixture model for longitudinal data with non-ignorable drop-outs.

    Science.gov (United States)

    Fitzmaurice, G M; Laird, N M; Shneyer, L

    2001-04-15

    This paper considers the mixture model methodology for handling non-ignorable drop-outs in longitudinal studies with continuous outcomes. Recently, Hogan and Laird have developed a mixture model for non-ignorable drop-outs which is a standard linear mixed effects model except that the parameters which characterize change over time depend also upon time of drop-out. That is, the mean response is linear in time, other covariates and drop-out time, and their interactions. One of the key attractions of the mixture modelling approach to drop-outs is that it is relatively easy to explore the sensitivity of results to model specification. However, the main drawback of mixture models is that the parameters that are ordinarily of interest are not immediately available, but require marginalization of the distribution of outcome over drop-out times. Furthermore, although a linear model is assumed for the conditional mean of the outcome vector given time of drop out, after marginalization, the unconditional mean of the outcome vector is not, in general, linear in the regression parameters. As a result, it is not possible to parsimoniously describe the effects of covariates on the marginal distribution of the outcome in terms of regression coefficients. The need to explicitly average over the distribution of the drop-out times and the absence of regression coefficients that describe the effects of covariates on the outcome are two unappealing features of the mixture modelling approach. In this paper we describe a particular parameterization of the general linear mixture model that circumvents both of these problems. Copyright 2001 John Wiley & Sons, Ltd.

  16. Quantifying Precipitation Loss of Radiation Belt Electrons during Storm-time and Non-Storm-Time Dropouts

    Science.gov (United States)

    Pham, K. H.; Tu, W.

    2016-12-01

    Relativistic electron flux in the radiation belt can drop by orders of magnitude within the timespan of a few hours. Studies of dropout events during geomagnetic storms are popular but relativistic electron flux dropouts are not always coupled to geomagnetic storms and can occur without the presence of one. In this study, we will be using a Drift-Diffusion model to simulate two contrasting radiation belt dropout events, both of which are GEM challenge events. The first event during 24 September 2013 is a non-storm time dropout event that has a Dst electron flux dropout occurs across all energies. Unlike the first event, the second event during 01 June 2013 has a Dst electrons that are less than 700 keV saw an enhancement while MeV electrons saw strong depletion. We use the Drift-Diffusion model, which includes the effects of azimuthal drift and pitch angle diffusion, to quantify the electron precipitation loss for both of these events. By simulating the low-altitude electron distributions observed by 6 NOAA/POES satellites, we resolve the precipitation loss with both high spatial and temporal resolution and at a range of energies. The estimated pitch angle diffusion rates from the model are then compared with in situ wave measurements from Van Allen Probes to uncover the underlying wave-particle-interaction mechanisms that are responsible for the fast electron precipitation. Comparing the resolved precipitation loss with the observed electron dropouts at high altitudes, our results will suggest the relative role of electron precipitation loss and outward radial diffusion to the radiation belt dropouts during storm and non-storm times, in addition to its energy and L dependence.

  17. The therapeutic alliance and therapist adherence as predictors of dropout from cognitive therapy for depression when combined with antidepressant medication.

    Science.gov (United States)

    Cooper, Andrew A; Strunk, Daniel R; Ryan, Elizabeth T; DeRubeis, Robert J; Hollon, Steven D; Gallop, Robert

    2016-03-01

    Previous psychotherapy research has examined the therapeutic alliance and therapist adherence as correlates or predictors of symptom change. While some initial evidence suggests the alliance is associated with risk of dropout in cognitive behavioral treatment for depression, evidence of such relations has been limited to date. We examined the relation of these psychotherapy process variables and dropout in the context of cognitive therapy for depression when provided in combination with pharmacotherapy. Patients were randomized to the CT plus pharmacotherapy condition of a clinical trial for chronic or recurrent depression. Consistent with the spirit of personalized medicine, patients were treated until they met remission and recovery criteria (or reached the maximum allowable time in the study). In a sample of 176 patients, we examined observer-rated alliance and therapist adherence in the first three CT sessions as potential predictors of treatment dropout. The therapeutic alliance and one facet of therapist adherence (i.e., Behavioral Methods/Homework) predicted reduced odds of dropout. Therapist use of Negotiating/Structuring predicted greater likelihood of dropout, but only when other variables were included in the model. Process ratings were not available for concurrent pharmacotherapy sessions. A minority of patients did not have session recordings available. Results are consistent with the possibility that the therapeutic alliance and therapists' focus on homework and behavioral methods promote treatment retention in combined treatment for depression. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Paradise lost or paradise regained? Changes in admission system affect academic performance and drop-out rates of medical students.

    Science.gov (United States)

    Kraft, Hans Georg; Lamina, Claudia; Kluckner, Thomas; Wild, Christoph; Prodinger, Wolfgang M

    2013-05-01

    The Austrian State medical universities had to change their admission system in 2005. Until this year admission to medical studies was unrestricted. Innsbruck Medical University chose the Eignungstest für das Medizinstudium in der Schweiz (EMS) aptitude test for admission testing. Did the implementation of a selection process affect the academic performance and drop-out rates of students according to gender? Two groups of students were compared: 'open admission' (2002-2004), and 'selected' (2006-2009). Academic performance was tested according to results in the final exams after year 1 (SIP 1; SIP, summative integrierte Prüfung) and after year 3 (SIP 3). Drop-out rates were recorded using the registration system of the university. Both, male and female 'selected' students had a higher passing rate regarding SIP 1 and they passed SIP 1 in shorter time and using fewer attempts than the open admission group. The percentage in passing SIP 3 did not change due to change in admission. The drop-out rates were significantly reduced for male and female students. 'Unselected' female students had a significantly higher drop-out ratio than 'unselected' male counterparts. After EMS testing, the drop-out ratios of female and male students were not significantly different. Selected applicants were more able and better motivated to study medicine.

  19. A package of interventions to reduce school dropout in public schools in a developing country. A feasibility study.

    Science.gov (United States)

    Graeff-Martins, Ana Soledade; Oswald, Sylvia; Comassetto, Júlia Obst; Kieling, Christian; Gonçalves, Renata Rocha; Rohde, Luis Augusto

    2006-12-01

    School dropout rates are staggeringly high in developing countries, even for elementary school children. This study aims to assess the feasibility and initial efficacy of a package of interventions tailored to reduce school dropout in public schools in an urban city in Brazil. Two public schools with similar high rates of dropout in elementary grades were selected. In one of them, a package of universal preventive interventions was implemented during a school year, including two workshops with teachers, five informative letters to parents, three meetings with parents at school, a telephone helpline at school, and a 1-day cognitive intervention. For children who stayed ten consecutive days out of school without reason, mental health assessment and referral to mental health services in the community were offered. In the second school, no intervention was implemented. After this 1-year intervention, there were significant differences between the two schools in rates of both dropout (P school, 18 (45%) youths returned to school after intervention among the 40 at-risk students. Moderate engagement of school staff was the main logistic problem. Our findings suggest that programs combining universal primary preventive strategies and interventions focused on at-risk students can be implemented and useful in developing countries to reduce school dropout.

  20. Magnetic susceptibilities of minerals

    Science.gov (United States)

    Rosenblum, Sam; Brownfield, I.K.

    2000-01-01

    Magnetic separation of minerals is a topic that is seldom reported in the literature for two reasons. First, separation data generally are byproducts of other projects; and second, this study requires a large amount of patience and is unusually tedious. Indeed, we suspect that most minerals probably are never investigated for this property. These data are timesaving for mineralogists who concentrate mono-mineralic fractions for chemical analysis, age dating, and for other purposes. The data can certainly be used in the ore-beneficiation industries. In some instances, magnetic-susceptibility data may help in mineral identification, where other information is insufficient. In past studies of magnetic separation of minerals, (Gaudin and Spedden, 1943; Tille and Kirkpatrick, 1956; Rosenblum, 1958; Rubinstein and others, 1958; Flinter, 1959; Hess, 1959; Baker, 1962; Meric and Peyre, 1963; Rojas and others, 1965; and Duchesne, 1966), the emphasis has been on the ferromagnetic and paramagnetic ranges of extraction. For readers interested in the history of magnetic separation of minerals, Krumbein and Pettijohn (1938, p. 344-346) indicated nine references back to 1848. The primary purpose of this paper is to report the magnetic-susceptibility data on as many minerals as possible, similar to tables of hardness, specific gravity, refractive indices, and other basic physical properties of minerals. A secondary purpose is to demonstrate that the total and best extraction ranges are influenced by the chemistry of the minerals. The following notes are offered to help avoid problems in separating a desired mineral concentrate from mixtures of mineral grains.

  1. Alcohol increases hypnotic susceptibility.

    Science.gov (United States)

    Semmens-Wheeler, Rebecca; Dienes, Zoltán; Duka, Theodora

    2013-09-01

    One approach to hypnosis suggests that for hypnotic experience to occur frontal lobe activity must be attenuated. For example, cold control theory posits that a lack of awareness of intentions is responsible for the experience of involuntariness and/or the subjective reality of hypnotic suggestions. The mid-dorso-lateral prefrontal cortex and the ACC are candidate regions for such awareness. Alcohol impairs frontal lobe executive function. This study examined whether alcohol affects hypnotisability. We administered 0.8 mg/kg of alcohol or a placebo to 32 medium susceptible participants. They were subsequently hypnotised and given hypnotic suggestions. All participants believed they had received some alcohol. Participants in the alcohol condition were more susceptible to hypnotic suggestions than participants in the placebo condition. Impaired frontal lobe activity facilitates hypnotic responding, which supports theories postulating that attenuation of executive function facilitates hypnotic response, and contradicts theories postulating that hypnotic response involves enhanced inhibitory, attentional or other executive function. Copyright © 2013. Published by Elsevier Inc.

  2. Diet and weight loss therapy dropout in bariatric patients: retrospective cohort in Lima, Peru

    Directory of Open Access Journals (Sweden)

    Monica Giacchetti-Vega

    2017-04-01

    Full Text Available Introduction: The aims of this study were to determine the proportion of patients who meet international recommendations for bariatric surgery and to assess the association between weight loss and dropout rate during diet therapy. Methods: Retrospective cohort study performed using data from clinical records of patients who underwent sleeve gastrectomy in a private clinic of Lima, Peru. Two outcomes were evaluated, eligibility for bariatric surgery according to international recommendations (BMI ≥40 kg/m2 or ≥35 kg/m2 with comorbidities and abandonment before and after starting nutritional management (no nutritional assessment after 60 days from the previous visit without achieving ideal BMI. The exposure was the percentage of weight lost in the first five weeks after surgery split into <10% and ≥10%. Poisson regression was used and relative risks and 95% confidence intervals (95%CI were calculated. Results: Data from 423 medical records of bariatric patients, mean age 39.2 years (±12.3, 294 (69.5% women, were analyzed. Only 117 (27.7% patients met international recommendations for bariatric surgery. Before starting nutritional management, 48/117 (41% abandoned treatment, whereas an additional 29/69 (42.0% abandoned before six months of nutritional management. Patient losing ≥10% of weight in the first month had 90% lower risk (RR = 0.10, 95% CI 0.01-0.68 of nutritional therapy dropout compared to those who lost <10% of weight, controlling for sex and age. Conclusions: A great proportion of patients undergoing bariatric surgery did not meet the international criteria. A greater loss of weight during the first month was associated a lower dropout rate during nutritional therapy.

  3. Correlates of pre-treatment drop-out among persons with marijuana dependence.

    Science.gov (United States)

    Vendetti, Janice; McRee, Bonnie; Miller, Michael; Christiansen, Kenneth; Herrell, James

    2002-12-01

    Our objective was to identify client characteristics and other factors associated with pre-treatment drop-out by people with marijuana dependence. Data from the Marijuana Treatment Project's screening assessment were used to examine correlates of pre-treatment drop-out. Information from all eligible study participants (n = 813) (i.e. those who were interested in receiving treatment for their marijuana dependence and were determined to be eligible for the randomized treatment efficacy trial) was used to examine differences between the 450 participants who initiated treatment (by enrolling in the trial) and the 363 individuals who declined enrollment. The study was conducted at three community-based outpatient treatment facilities in Farmington, CT, Seattle, WA and Miami, FL. The information gathered in the screening interview included demographic characteristics, residential stability variables, employment and education history and referral source. Substance use variables included the number of days and the number of times per day marijuana was used, self-perceived dependence on marijuana, alcohol or other drugs, other drug use history and current treatment (i.e. substance abuse, medical, psychiatric) situation. Stepwise logistic regression was conducted to confirm variables associated with treatment initiation in bivariate analyses. Pre-treatment drop-out was associated with being younger, unmarried, unemployed, less educated and Asian American or Native American. It was also associated with self-perceived dependence on marijuana and use of other drugs. By recognizing demographic and substance use factors that may serve as barriers for individuals accessing treatment for marijuana dependence, clinicians may target clients with these characteristics proactively to encourage treatment initiation and subsequent attendance.

  4. School motivation and high school dropout: the mediating role of educational expectation.

    Science.gov (United States)

    Fan, Weihua; Wolters, Christopher A

    2014-03-01

    A good deal of evidence indicates that students' motivational beliefs and attitudes play a critical role in their academic success. Research studies on how motivational factors may help determine whether students remain in high school or drop out, however, are relatively few. More specifically, there is a lack of research examining the dynamics of whether students' motivational beliefs from earlier in high school might be used to predict their status as a dropout in their final year. The aim of the present study was to examine the mediating role of students' educational expectations in linking students' school motivation to their dropout status by utilizing a nationally representative dataset. The present study used data from the Educational Longitudinal Study of 2002 (ELS: 2002). The final sample consisted of 16,194 students, with approximately 54% White, 13% Black, 16% Hispanic, and 10% Asian students, and the rest were Native American, Hawaiian, multiracial, or of other races. Structural equation modelling was employed to conduct the mediational analysis. The results of the present study demonstrated that the relationships between student ability beliefs in math and English and student behaviour of dropping out were fully mediated by students' educational expectations. The results also revealed that student intrinsic value in math and English had significant indirect relations with student behaviour of leaving school through students' educational expectations. The results of this study suggest that explanations for student dropout status that rely solely on students' social background and school behaviours without considering their motivation are incomplete. The study expands the extant research by showing possible pathways that motivate students to persist in high school. These pathways are specifically rooted in students' ability beliefs and intrinsic interest in learning through their relationships with students' expectations for their education. © 2012 The

  5. Cigarette Smoking Trajectories From Sixth to Twelfth Grade: Associated Substance Use and High School Dropout.

    Science.gov (United States)

    Orpinas, Pamela; Lacy, Beth; Nahapetyan, Lusine; Dube, Shanta R; Song, Xiao

    2016-02-01

    The purpose of this longitudinal study was to identify distinct trajectories of cigarette smoking from sixth to twelfth grade and to characterize these trajectories by use of other drugs and high school dropout. The diverse sample for this analysis consisted of a cohort of 611 students from Northeast Georgia who participated in the Healthy Teens Longitudinal Study (2003-2009). Students completed seven yearly assessments from sixth through twelfth grade. We used semi-parametric, group-based modeling to identify groups of students whose smoking behavior followed a similar progression over time. Current smoking (past 30 day) increased from 6.9% among sixth graders to 28.8% among twelfth graders. Four developmental trajectories of cigarette smoking were identified: Abstainers/Sporadic Users (71.5% of the sample), Late Starters (11.3%), Experimenters (9.0%), and Continuous Users (8.2%). The Abstainer/Sporadic User trajectory was composed of two distinct groups: those who never reported any tobacco use (True Abstainers) and those who reported sporadic, low-level use (Sporadic Users). The True Abstainers reported significantly less use of alcohol and other drugs and lower dropout rates than students in all other trajectories, and Sporadic Users had worse outcomes than True Abstainers. Experimenters and Continuous Users reported the highest drug use. Over one-third of Late Starters (35.8%) and almost half of Continuous Users (44.4%) dropped out of high school. Cigarette smoking was associated with behavioral and academic problems. Results support early and continuous interventions to reduce use of tobacco and other drugs and prevent high school dropout. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Comparison of personal, social and academic variables related to University Dropout and Persistence

    Directory of Open Access Journals (Sweden)

    Ana B. Bernardo

    2016-10-01

    Full Text Available Dropping out of university has serious consequences not only for the student who drops out but also for the institution and society as a whole. Although this phenomenon has been widely studied, there is a need for broader knowledge of the context in which it occurs. Yet research on the subject often focuses on variables that, although they affect drop-out rates, lie beyond a university's control. This makes it hard to come up with effective preventive measures. That is why a northern Spanish university has undertaken a ex post facto holistic research study on 1,311 freshmen (2008/9, 2009/10 and 2010/11 cohorts. The study falls within the framework of the ALFA-GUIA European Project and focuses on those drop-out factors where there is scope for taking remedial measures. This research explored the possible relationship of degree dropout and different categories of variables: variables related to the educational stage prior to university entry (path to entry university and main reason for degree choice, variables related to integration and coexistence at university (social integration, academic integration, relationships with teachers/ peers and value of the living environment financial status and performance during university studies (in terms ofcompliance with the program, time devoted to study, use of study techniques and class attendance. Descriptive, correlational and variance analyses were conducted to discover which of these variables really distinguish those students who drop out from their peers who complete their studies. Results highlight the influence of vocation as main reason for degree choice, path to university entry, financial independency, social and academic adaptation, time devoted to study, use of study techniques and program compliance in the studied phenomenon.

  7. Patient Profile of Drop-Outs From a Pulmonary Rehabilitation Program.

    Science.gov (United States)

    Almadana Pacheco, Virginia; Pavón Masa, María; Gómez-Bastero Fernández, Ana Paulina; Muñiz Rodríguez, Ana Mirian; Tallón Moreno, Rodrigo; Montemayor Rubio, Teodoro

    2017-05-01

    While the benefits of pulmonary rehabilitation programs (PR) in COPD have been demonstrated, poor adherence, related with worse clinical outcomes, is common. The purpose of this study was to examine causes for drop-out during a 12-week multidisciplinary pulmonary rehabilitation program and to investigate the characteristics of patients with poor adherence, with special emphasis on functional and clinical characteristics. A prospective study was performed between February and November 2015in 83 COPD patients enrolled in an outpatient program of 36 strength +resistance training sessions. Ambulances were provided to facilitate access to the clinic. Patients were divided into: adherent (A) (attended at least 70% of the program) or non-adherent (NA) (at least one session). A total of 83 patients were evaluated and 26 excluded; 15.7% refused to participate. The drop-out rate was 38.5%. The main causes were low motivation and transport problems. Lower forced vital capacity (NA, 58.9% vs A, 67.8%; P=.03), worse results on submaximal exercise test (NA, 6.2minutes vs A, 9.2minutes; P=.02), in total distance walked (NA, 42.6 vs A, 56.5; P=.03) and VO2 in ml/min/kg (NA, 11.4 vs A, 13.6; P=.03) and in ml/min (NA, 839 vs A, 1020; P=.04) were found in the non-adherent group. This group also showed higher use of oral steroids (NA, 23.8% vs A, 2.9%; P=.01). More than 1/3 of patients leave programs. The main causes are related to motivation and transport. The patients who dropout are those with worse functional tests, more exacerbations, steroids and smoking habit. Copyright © 2016 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. New Governance: Pitfalls of Activation Policies for Young Migrant Dropouts in the Netherlands

    Directory of Open Access Journals (Sweden)

    Debby Gerritsen

    2011-12-01

    Full Text Available Migrant youth are at a disadvantage in the Netherlands when it comes to schooling and work: many drop out of school and are unemployed. We will use concepts of new governance to discuss the complexities surrounding the execution of policies to reintegrate dropouts back into school or the labour market from the perspectives of professionals (street level bureaucrats working in activation programmes. The results show that cooperation is difficult. The most difficult youngsters are beyond the reach of most policy initiatives. Furthermore, many professionals perceive educational requirements as unrealistic for some youngsters. Finally, new requirements for employability may stigmatize youngsters as unwilling and unmotivated.

  9. Impact of Dupoto-e-Maa education project on dropout rate and academic performance

    Directory of Open Access Journals (Sweden)

    James B. Ouda

    2016-06-01

    Full Text Available Background: A study conducted in the Kajiado Central District of Kenya in 2006 showed that there was a high dropout rate among primary schoolgoing children and that their academic performance was poor. The Dupoto-e-Maa education project was implemented in 2007 to address issues related to drop out rate and academic performance.Objectives: The evaluation therefore investigated the extent to which the project had influenced dropout rate and academic performance in the public primary schools in Kajiado Central District.Method: The evaluation adopted a mixed methods approach: cross-sectional survey and case study designs. The benefit of the approach is the richness of information obtained through triangulation. The respondents included head teachers, school management committees, teachers, pupils, quality assurance and standards officer and project staff. A sample size of 183 respondents was selected using purposive sampling and stratified random sampling procedures. Head teachers of the sampled schools participated as key informants. The instruments of data collection included questionnaires, an interview guide, a document analysis guide, a focus group discussion guide and an observation guide. Results: The findings indicate that the Dupoto-e-Maa education project had influenced dropout rates. The direction of the findings seems to suggest that academic performance trends are unpredictable since fluctuations are evident, though the programme could have encountered some challenges that may have limited its achievement on this variable.Conclusion: The study recommended that there is need to increase the number of non-governmental organisations modelled around the Dupoto-e-Maa education project so as to reduce dropout rate and improve pupil academic performance. The findings could also inform government policy in terms of recruitment and placement of teachers in schools in arid and semi-arid lands. Project funding could be increased

  10. Segmentation of intracranial arterial calcification with deeply supervised residual dropout networks

    DEFF Research Database (Denmark)

    Bortsova, Gerda; van Tulder, Gijs; Dubost, Florian

    2017-01-01

    convolutional neural network that we extend with two regularization techniques. Firstly, we use deep supervision to encourage discriminative features in the hidden layers. Secondly, we augment the network with skip connections, as in the recently developed ResNet, and dropout layers, inserted in a way that skip...... using 882 CT scans and test on 1,000. Our regularization techniques and objective improve the average Dice score by 7.1%, yielding an average Dice of 76.2% and 97.7% correlation between predicted ICAC volumes and manual annotations....

  11. A dropout-regularised neural network for mapping arsenic enrichment in SW England using MXNet

    OpenAIRE

    Kirkwood, Charlie

    2016-01-01

    This poster applies a dropout-regularised artifical neural network, constructed in the MXNet framework, to map arsenic enrichment in south west England. The network models the relationships between arsenic (as a centred log-ratio from XRF analyses of 3395 stream sediment samples) and high resolution geophysical data. The resultant model, trained to optimal accuracy using early stopping, achieves an R2 of 0.7 on held-out test data - a promising level of accuracy for predictions in a complex hy...

  12. Policy and participant perspectives on the drop-out problem in secondary education

    DEFF Research Database (Denmark)

    Rasmussen, Annette; Rasmussen, Palle

    In this paper we compare the way the drop-out problem in secondary education is constructed in Danish official and public policy discourse with the way it is experiences and interpreted by young people trying to get an education. As regards the student's perspective we will use interviews...... with students in production schools. This is an interim form of schooling for young people who have for some reason not entered secondary education directly but are still trying to find their way into (most often) vocational education....

  13. Fractal-Based Oscillation of Macular Arteriogenesis and Dropout During Progressive Diabetic Retinopathy

    Science.gov (United States)

    Radharkrishnan, Krishnan; Kaiser, Peter K.

    2011-01-01

    By both fractal (D1) and branching (Lv) analysis, macular arterial density oscillated with progression from mild NPDR to PDR. Results are consistent with out study reported recently for the entire arterial and venous branching trees within 50 degree FAs by VESGEN generational branching analysis. Current and previous results are important for advances in early-stage regenerative DR therapies, for which reversal of DR progression to a normal vessel density may be possible. For example, potential use of regenerative angiogenesis stimulators to reverse vascular dropout during mild and severe NPDR is not indicated for treatment of moderate NPDR.

  14. Robust Fault-Tolerant Control for Uncertain Networked Control Systems with State-Delay and Random Data Packet Dropout

    Directory of Open Access Journals (Sweden)

    Xiaomei Qi

    2012-01-01

    Full Text Available A robust fault-tolerant controller design problem for networked control system (NCS with random packet dropout in both sensor-to-controller link and controller-to-actuator link is investigated. A novel stochastic NCS model with state-delay, model uncertainty, disturbance, probabilistic sensor failure, and actuator failure is proposed. The random packet dropout, sensor failures, and actuator failures are characterized by a binary random variable. The sufficient condition for asymptotical mean-square stability of NCS is derived and the closed-loop NCS satisfies H∞ performance constraints caused by the random packet dropout and disturbance. The fault-tolerant controller is designed by solving a linear matrix inequality. A numerical example is presented to illustrate the effectiveness of the proposed method.

  15. A mixed methods investigation of dropout among talented young dancers: findings from the UK Centres for Advanced Training.

    Science.gov (United States)

    Walker, Imogen J; Nordin-Bates, Sanna M; Redding, Emma

    2012-01-01

    The aim of this study was to understand reasons for dropout from a dance-talent program in the UK, using a mixed methods design. In-depth interviews were conducted with ten dropout students to explore the influencing factors in their decision to leave the program. In order to triangulate these findings, reasons for dropout were then examined from descriptive records of 147 young dancers who had withdrawn from the talent program over a four-year period. Overall, the most frequently cited reasons for dropping out were conflicting demands, change in aspirations, course content, difficulty making friends, and lost passion. Injury, financial factors, low perceived competence, and teacher behavior emerged as minor reasons. Intervention strategies that focus on changes in course content may be the easiest to implement and most effective means to enhance student retention.

  16. Graphene susceptibility in Holstein model

    Energy Technology Data Exchange (ETDEWEB)

    Mousavi, Hamze, E-mail: hamze.mousavi@gmail.co [Department of Physics, Razi University, Kermanshah (Iran, Islamic Republic of); Nano Science and Nano Technology Research Center, Razi University, Kermanshah (Iran, Islamic Republic of)

    2011-06-15

    We study the effects of the electron-phonon interaction on the temperature dependence of the orbital magnetic susceptibility of monolayer graphene. We use the linear response theory and Green's function formalism within the Holstein Hamiltonian model. The results show that the effects of the electron-phonon interaction on the susceptibility of graphene sheet have different behaviors in two temperature regions. In the low temperature region, susceptibility increases when the electron-phonon coupling strength increases. On the other hand, the susceptibility reduces with increasing the electron-phonon coupling strength in the high temperature region. - Highlights: Effect of electron-phonon interaction on the susceptibility of graphene is studied. Linear response theory and Green's function technique in Holstein model are used. Effect of electron-phonon on susceptibility has different behaviors in two temperature regions.

  17. Internet-based motivation program for women with eating disorders: eating disorder pathology and depressive mood predict dropout.

    Science.gov (United States)

    von Brachel, Ruth; Hötzel, Katrin; Hirschfeld, Gerrit; Rieger, Elizabeth; Schmidt, Ulrike; Kosfelder, Joachim; Hechler, Tanja; Schulte, Dietmar; Vocks, Silja

    2014-03-31

    One of the main problems of Internet-delivered interventions for a range of disorders is the high dropout rate, yet little is known about the factors associated with this. We recently developed and tested a Web-based 6-session program to enhance motivation to change for women with anorexia nervosa, bulimia nervosa, or related subthreshold eating pathology. The aim of the present study was to identify predictors of dropout from this Web program. A total of 179 women took part in the study. We used survival analyses (Cox regression) to investigate the predictive effect of eating disorder pathology (assessed by the Eating Disorders Examination-Questionnaire; EDE-Q), depressive mood (Hopkins Symptom Checklist), motivation to change (University of Rhode Island Change Assessment Scale; URICA), and participants' age at dropout. To identify predictors, we used the least absolute shrinkage and selection operator (LASSO) method. The dropout rate was 50.8% (91/179) and was equally distributed across the 6 treatment sessions. The LASSO analysis revealed that higher scores on the Shape Concerns subscale of the EDE-Q, a higher frequency of binge eating episodes and vomiting, as well as higher depression scores significantly increased the probability of dropout. However, we did not find any effect of the URICA or age on dropout. Women with more severe eating disorder pathology and depressive mood had a higher likelihood of dropping out from a Web-based motivational enhancement program. Interventions such as ours need to address the specific needs of women with more severe eating disorder pathology and depressive mood and offer them additional support to prevent them from prematurely discontinuing treatment.

  18. Topological susceptibility from slabs

    Energy Technology Data Exchange (ETDEWEB)

    Bietenholz, Wolfgang [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, A.P. 70-543, Distrito Federal, C.P. 04510 (Mexico); Forcrand, Philippe de [Institute for Theoretical Physics, ETH Zürich,CH-8093 Zürich (Switzerland); CERN, Physics Department, TH Unit, CH-1211 Geneva 23 (Switzerland); Gerber, Urs [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, A.P. 70-543, Distrito Federal, C.P. 04510 (Mexico); Instituto de Física y Matemáticas, Universidad Michoacana de San Nicolás de Hidalgo,Edificio C-3, Apdo. Postal 2-82, Morelia, Michoacán, C.P. 58040 (Mexico)

    2015-12-14

    In quantum field theories with topological sectors, a non-perturbative quantity of interest is the topological susceptibility χ{sub t}. In principle it seems straightforward to measure χ{sub t} by means of Monte Carlo simulations. However, for local update algorithms and fine lattice spacings, this tends to be difficult, since the Monte Carlo history rarely changes the topological sector. Here we test a method to measure χ{sub t} even if data from only one sector are available. It is based on the topological charges in sub-volumes, which we denote as slabs. Assuming a Gaussian distribution of these charges, this method enables the evaluation of χ{sub t}, as we demonstrate with numerical results for non-linear σ-models.

  19. Topological Susceptibility from Slabs

    CERN Document Server

    Bietenholz, Wolfgang; Gerber, Urs

    2015-01-01

    In quantum field theories with topological sectors, a non-perturbative quantity of interest is the topological susceptibility chi_t. In principle it seems straightforward to measure chi_t by means of Monte Carlo simulations. However, for local update algorithms and fine lattice spacings, this tends to be difficult, since the Monte Carlo history rarely changes the topological sector. Here we test a method to measure chi_t even if data from only one sector are available. It is based on the topological charges in sub-volumes, which we denote as slabs. Assuming a Gaussian distribution of these charges, this method enables the evaluation of chi_t, as we demonstrate with numerical results for non-linear sigma-models.

  20. Predictors of treatment dropout in self-guided web-based interventions for depression : An 'individual patient data' meta-analysis

    NARCIS (Netherlands)

    Karyotaki, E.; Kleiboer, A.; Smit, F.; Turner, D. T.; Pastor, A. M.; Andersson, G.; Berger, T.; Botella, C.; Breton, J. M.; Carlbring, P.; Christensen, H.; de Graaf, E.; Griffiths, K.; Donker, T.; Farrer, L.; Huibers, M. J. H.; Lenndin, J.; Mackinnon, A.; Meyer, B.; Moritz, S.; Riper, H.; Spek, V.; Vernmark, K.; Cuijpers, P.

    2015-01-01

    It is well known that web-based interventions can be effective treatments for depression. However, dropout rates in web-based interventions are typically high, especially in self-guided web-based interventions. Rigorous empirical evidence regarding factors influencing dropout in self-guided

  1. Analysis of the Socio-Economic Factors That Contribute to Children School Dropout in Artisanal Small-Scale Gold Mining Communities of Tanzania

    Science.gov (United States)

    Ouma, Dora Harrison; Ting, Zuo; Pesha, John Chrisostom

    2017-01-01

    In Tanzania, education has been earmarked as a priority area to stimulate socioeconomic development, however; the increasing number of school dropout cases is posing a huge hindrance to achieving this goal. To establish the major causes of school dropouts, this paper investigated different factors that explain the phenomena with special focus on…

  2. The Impact of the Correlation between the No Child Left Behind Act's High Stakes Testing and the High Drop-Out Rates of Minority Students

    Science.gov (United States)

    Walden, Lavada M.; Kritsonis, William Allan

    2008-01-01

    The author looks at critical dialogue surrounding the causes for the alarming high numbers of high school dropouts in states that use high stakes standardized testing mandated by the No Child Left Behind Act, and investigates the perceived correlations between high stakes testing and high numbers of high school dropouts of minority students.

  3. Trends in High School Dropout and Completion Rates in the United States: 1972-2012. Compendium Report. NCES 2015-015

    Science.gov (United States)

    Stark, Patrick; Noel, Amber M.

    2015-01-01

    This report builds upon a series of National Center for Education Statistics (NCES) reports on high school dropout and completion rates that began in 1988. It presents estimates of rates in 2012, provides data about trends in dropout and completion rates over the last four decades (1972-2012), and examines the characteristics of high school…

  4. Trends in High School Dropout and Completion Rates in the United States: 1972-2008. Compendium Report. NCES 2011-012

    Science.gov (United States)

    Chapman, Chris; Laird, Jennifer; KewalRamani, Angelina

    2010-01-01

    This report builds upon a series of National Center for Education Statistics (NCES) reports on high school dropout and completion rates that began in 1988. It presents estimates of rates in 2008, provides data about trends in dropout and completion rates over the last three and a half decades (1972-2008), and examines the characteristics of high…

  5. Novel disease susceptibility factors for fungal necrotrophic pathogens in Arabidopsis.

    Directory of Open Access Journals (Sweden)

    Albor Dobón

    2015-04-01

    Full Text Available Host cells use an intricate signaling system to respond to invasions by pathogenic microorganisms. Although several signaling components of disease resistance against necrotrophic fungal pathogens have been identified, our understanding for how molecular components and host processes contribute to plant disease susceptibility is rather sparse. Here, we identified four transcription factors (TFs from Arabidopsis that limit pathogen spread. Arabidopsis mutants defective in any of these TFs displayed increased disease susceptibility to Botrytis cinerea and Plectosphaerella cucumerina, and a general activation of non-immune host processes that contribute to plant disease susceptibility. Transcriptome analyses revealed that the mutants share a common transcriptional signature of 77 up-regulated genes. We characterized several of the up-regulated genes that encode peptides with a secretion signal, which we named PROVIR (for provirulence factors. Forward and reverse genetic analyses revealed that many of the PROVIRs are important for disease susceptibility of the host to fungal necrotrophs. The TFs and PROVIRs identified in our work thus represent novel genetic determinants for plant disease susceptibility to necrotrophic fungal pathogens.

  6. Mental health and school dropout across educational levels and genders: a 4.8-year follow-up study.

    Science.gov (United States)

    Hjorth, Cathrine F; Bilgrav, Line; Frandsen, Louise Sjørslev; Overgaard, Charlotte; Torp-Pedersen, Christian; Nielsen, Berit; Bøggild, Henrik

    2016-09-15

    Education is a key determinant of future employment and income prospects of young people. Poor mental health is common among young people and is related to risk of dropping out of school (dropout). Educational level and gender might play a role in the association, which remains to be studied. Mental health was measured in 3146 Danish inhabitants aged 16-29 years using the 12-Item Short-Form Health Survey and examined across genders and educational levels. For students, educational level at baseline was used; for young people who were not enrolled in school at baseline (non-students), the highest achieved educational level was used. The risk of dropout in students was investigated in administrative registers over a 4.8-year period (1(st) March 2010-31(th) December 2014). Odds ratios (OR) and 95 % confidence intervals (CI) were calculated for mental health and in relation to dropout in logistic regression models, adjusting for age, gender, educational level, parental education, parental income and ethnicity. Poor mental health was present in 24 % (n = 753) of the participants, 29 % (n = 468) in females and 19 % (n = 285) in males (p Dropout occurred in 8 % (n = 124) of the students. Poor mental health was associated to dropout in vocational (OR = 1.8, CI = 1.0-3.2) and higher education (OR = 2.0, CI = 1.0-4.2). For males in higher education, poor mental health was a predictor of dropout (OR = 5.2, CI = 1.6-17.3), which was not seen females in higher education (OR = 1.2, CI = 0.5-3.1). Poor mental health was significantly associated to dropout among students in vocational and higher education. Males in higher education had five times the risk of dropout when reporting poor mental health, while no such association was found for females.

  7. Information Management Processes for Extraction of Student Dropout Indicators in Courses in Distance Mode

    Directory of Open Access Journals (Sweden)

    Renata Maria Abrantes Baracho

    2016-04-01

    Full Text Available This research addresses the use of information management processes in order to extract student dropout indicators in distance mode courses. Distance education in Brazil aims to facilitate access to information. The MEC (Ministry of Education announced, in the second semester of 2013, that the main obstacles faced by institutions offering courses in this mode were students dropping out and the resistance of both educators and students to this mode. The research used a mixed methodology, qualitative and quantitative, to obtain student dropout indicators. The factors found and validated in this research were: the lack of interest from students, insufficient training in the use of the virtual learning environment for students, structural problems in the schools that were chosen to offer the course, students without e-mail, incoherent answers to activities to the course, lack of knowledge on the part of the student when using the computer tool. The scenario considered was a course offered in distance mode called Aluno Integrado (Integrated Student

  8. Dropout Rates and Response Times of an Occupation Search Tree in a Web Survey

    Directory of Open Access Journals (Sweden)

    Tijdens Kea

    2014-03-01

    Full Text Available Occupation is key in socioeconomic research. As in other survey modes, most web surveys use an open-ended question for occupation, though the absence of interviewers elicits unidentifiable or aggregated responses. Unlike other modes, web surveys can use a search tree with an occupation database. They are hardly ever used, but this may change due to technical advancements. This article evaluates a three-step search tree with 1,700 occupational titles, used in the 2010 multilingual WageIndicator web survey for UK, Belgium and Netherlands (22,990 observations. Dropout rates are high; in Step 1 due to unemployed respondents judging the question not to be adequate, and in Step 3 due to search tree item length. Median response times are substantial due to search tree item length, dropout in the next step and invalid occupations ticked. Overall the validity of the occupation data is rather good, 1.7-7.5% of the respondents completing the search tree have ticked an invalid occupation.

  9. Associations between reasons to attend and late-high school dropout.

    Science.gov (United States)

    Abar, Beau; Abar, Caitlin C; Lippold, Melissa; Powers, Christopher J; Manning, Alice E

    2012-12-01

    This study addressed (1) whether there were unique profiles of student self-reported reasons for attending school among 10(th) graders, (2) whether these profiles were differentially associated with late high-school dropout, and (3) whether parent characteristics differed across profiles. Using data from the Educational Longitudinal Study of 2002 (N = 15,362), five latent classes were found. The first class (49%) reported intrinsic, identified/introjected, and external motivations for attending school. The second class (32%) attended for identified/introjected and external reasons, while the third class (11%) reported intrinsic and identified/introjected reasons. The final two classes reported only identified/introjected (5%) or external (4%) motivations. Individuals in the identified/introjected and external classes were at greatest risk of dropping out between 10(th) and 12(th) grade. A host of parenting characteristics differed across class, with students in the intrinsic-identified/introjected-external class displaying the most favorable pattern of results. Implications for dropout prevention and academic promotion programs are discussed.

  10. Migrants referring to the Bologna Transcultural Psychiatric Team: reasons for drop-out.

    Science.gov (United States)

    Tarricone, Ilaria; Atti, Anna Rita; Braca, Mauro; Pompei, Graziano; Morri, Michela; Poggi, Francesca; Melega, Saverio; Stivanello, Elisa; Tonti, Lorenza; Nolet, Maria; Berardi, Domenico

    2011-11-01

    Recent immigrants face various difficulties in adjusting to western countries and show a high prevalence of mental disorders. Access to a culturally appropriate community mental health centre (CMHC) is crucial for immigrants (Bhui et al., 2007). The Bologna West Transcultural Psychiatric Team (BoTPT, Tarricone et al., 2009) is one of the first projects in Italy that prioritizes cultural competence care. This paper aims to evaluate the effectiveness of this service and to describe what characteristics of patient and psychiatric intervention are related to 'drop-out'. All migrants who consecutively attended the BoTPT between 1 July 1999 and 30 June 2008 were included and evaluated at first contact and again six months later. After six months we followed up 162 patients; 32 (17.9%) of these had interrupted treatment. Non-Asian origin, a recent history of migration and not receiving social intervention were the strongest predictors of drop-out cases. Psychiatric consultation services to migrants could be made more effective by enhancing: (a) cultural competence, through cultural mediator involvement; and (b) social support from the first psychiatric contact. These two characteristics of psychiatric consultation could be developed from resources ordinarily present in the context of a CMHC and could then become a cost-effective strategy for addressing mental health needs among first-generation immigrants.

  11. Radial diffusion simulations of the 20 September 2007 radiation belt dropout

    Directory of Open Access Journals (Sweden)

    J. Albert

    2014-08-01

    Full Text Available This is a study of a dropout of radiation belt electrons, associated with an isolated solar wind density pulse on 20 September 2007, as seen by the solid-state telescopes (SST detectors on THEMIS (Time History of Events and Macroscale Interactions during Substorms. Omnidirectional fluxes were converted to phase space density at constant invariants M = 700 MeV G−1 and K = 0.014 RE G1/2, with the assumption of local pitch angle α ≈ 80° and using the T04 magnetic field model. The last closed drift shell, which was calculated throughout the time interval, never came within the simulation outer boundary of L* = 6. It is found, using several different models for diffusion rates, that radial diffusion alone only allows the data-driven, time-dependent boundary values at Lmax = 6 and Lmin = 3.7 to propagate a few tenths of an RE during the simulation; far too slow to account for the dropout observed over the broad range of L* = 4–5.5. Pitch angle diffusion via resonant interactions with several types of waves (chorus, electromagnetic ion cyclotron waves, and plasmaspheric and plume hiss also seems problematic, for several reasons which are discussed.

  12. The peculiarities of ICT students‘ drop-out because of academic arrears

    Directory of Open Access Journals (Sweden)

    Saulius Preidys

    2015-09-01

    Full Text Available Lack of ICT specialists is a big problem in Lithuania for many years. Even ICT specialists are prepared both by universities and colleges, need of those specialists is increasing every year. Students’ enrolment to the ICT related study programmes is increasing a little every year, but only around 51% of them complete their studies. There are very different reasons of students drop-out: health problems, characteristics of personality (lack of responsibility, self-doubts, etc., socio-economic factors, organisation of study process (Barkauskaitė & Gudžinskienė 2006. In this article a different approach is used to academic arrears – using statistical calculations, academic arrears of students of Vilnius University, Faculty of Mathematics and Informatics from 1991 till 2012 are analysed. At the end of the article, justification of a theoretical model is presented, using which students’ drop-out peculiarities in different study programmes can be observed.DOI: 10.15181/csat.v3i2.1114

  13. Fast DCNN based on FWT, intelligent dropout and layer skipping for image retrieval.

    Science.gov (United States)

    ElAdel, Asma; Zaied, Mourad; Amar, Chokri Ben

    2017-11-01

    Deep Convolutional Neural Network (DCNN) can be marked as a powerful tool for object and image classification and retrieval. However, the training stage of such networks is highly consuming in terms of storage space and time. Also, the optimization is still a challenging subject. In this paper, we propose a fast DCNN based on Fast Wavelet Transform (FWT), intelligent dropout and layer skipping. The proposed approach led to improve the image retrieval accuracy as well as the searching time. This was possible thanks to three key advantages: First, the rapid way to compute the features using FWT. Second, the proposed intelligent dropout method is based on whether or not a unit is efficiently and not randomly selected. Third, it is possible to classify the image using efficient units of earlier layer(s) and skipping all the subsequent hidden layers directly to the output layer. Our experiments were performed on CIFAR-10 and MNIST datasets and the obtained results are very promising. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. High school dropout and long-term sickness and disability in young adulthood: a prospective propensity score stratified cohort study (the Young-HUNT study).

    Science.gov (United States)

    De Ridder, Karin A A; Pape, Kristine; Cuypers, Koenraad; Johnsen, Roar; Holmen, Turid Lingaas; Westin, Steinar; Bjørngaard, Johan Håkon

    2013-10-09

    High school dropout and long-term sickness absence/disability pension in young adulthood are strongly associated. We investigated whether common risk factors in adolescence may confound this association. Data from 6612 school-attending adolescents (13-20 years old) participating in the Norwegian Young-HUNT1 Survey (1995-1997) was linked to long-term sickness absence or disability pension from age 24-29 years old, recorded in the Norwegian Labour and Welfare Organisation registers (1998-2008). We used logistic regression to estimate risk differences of sickness or disability for school dropouts versus completers, adjusting for health, health-related behaviours, psychosocial factors, school problems, and parental socioeconomic position. In addition, we stratified the regression models of sickness and disability following dropout across the quintiles of the propensity score for high school dropout. The crude absolute risk difference for long-term sickness or disability for a school dropout compared to a completer was 0.21% or 21% points (95% confidence interval (CI), 17 to 24). The adjusted risk difference was reduced to 15% points (95% CI, 12 to 19). Overall, high school dropout increased the risk for sickness or disability regardless of the risk factor level present for high school dropout. High school dropouts have a strongly increased risk for sickness and disability in young adulthood across all quintiles of the propensity score for dropout, i.e. independent of own health, family and socioeconomic factors in adolescence. These findings reveal the importance of early prevention of dropout where possible, combined with increased attention to labour market integration and targeted support for those who fail to complete school.

  15. Factors associated with non-participation and drop-out in a lifestyle intervention for workers with an elevated risk of cardiovascular disease.

    Science.gov (United States)

    Groeneveld, Iris F; Proper, Karin I; van der Beek, Allard J; Hildebrandt, Vincent H; van Mechelen, Willem

    2009-12-01

    Non-response and drop-out are problems that are commonly encountered in health promotion trials. Understanding the health-related characteristics of non-participants and drop-outs and the reasons for non-participation and drop-out may be beneficial for future intervention trials. Male construction workers with an elevated risk of cardiovascular disease (CVD) were invited to participate in a lifestyle intervention study. In order to investigate the associations between participation and CVD risk factors, and drop-out and CVD risk factors, crude and multiple logistic regression analyses were performed. The reasons for non-participation and drop-out were assessed qualitatively. 20% of the workers who were invited decided to participate; 8.6% of the participants dropped out before the first follow-up measurement. The main reasons for non-participation were 'no interest', 'current (para-)medical treatment', and 'feeling healthy', and for drop-out they were 'lack of motivation', 'current (para-)medical treatment', and 'disappointment'. Participants were 4.2 years older, had a higher blood pressure, higher total cholesterol, and lower HDL cholesterol than non-participants, and were more likely to report 'tiredness and/or stress' and 'chest pain and/or shortness of breath'. After adjusting for age, most risk factors were not significantly associated with participation. Drop-outs were 4.6 years younger than those who completed the study. The prevalence of smoking was higher among non-participants and drop-outs. Participants had a worse CVD risk profile than non-participants, mainly because of the difference in age. Non-participants and drop-outs were younger and more likely to be smokers. The main reasons for non-participation and drop-out were health-related. Investigators in the field of health promotion should be encouraged to share comparable information. Current Controlled Trials ISRCTN60545588.

  16. Role of magnetic susceptibility weighted imaging in evaluation of ...

    African Journals Online (AJOL)

    Introduction: Susceptibility-weighted imaging (SWI) is a new method in MR imaging. SWI detects the signal loss created by disturbance of a homogeneous magnetic field; these disturbances can be caused by paramagnetic, ferromagnetic, or diamagnetic substances. There are many neurologic conditions that can benefit ...

  17. Microwave susceptibility experiments

    Energy Technology Data Exchange (ETDEWEB)

    McConaghy, C.

    1984-05-29

    In certain experimental environments, systems can be affected or damaged by microwave pulses. I have conducted tests at LLNL to understand the phenomenology of microwave susceptibility of system components and subsystem components. To date, my experiments have concentrated on bipolar transistors, similar to what might be used in discrete analog circuits, and on CMOS RAM chips, which might be used in a computer memory system. I observed a decrease in failure energies for both the transistor and the integrated curcuit as I shortened the microwave pulse width. An S band (2.86 GHz) transmit/receive (T/R) tube has also been tested both at S band and at X band (8.16 GHz). The S band pulse had limitations in rise-time from zero power, which had an effect on the amount of power that could be transmitted through the T/R tube, as much as 0.7% of the incident power passed through the tube. All tests were conducted in closed-waveguide or coax test-fixtures, in contrast to the anechoic chambers utilized by other experimenters. I have used both S band and X band Klystron generators. For very high power (greater than 1 MW), I used an additional pulse-compression cavity at S band. Other subsystem components such as an X band mixer and an X band T/R tube will be tested in the future. 8 references.

  18. [Antimicrobial susceptibility cumulative reports].

    Science.gov (United States)

    Canut-Blasco, Andrés; Calvo, Jorge; Rodríguez-Díaz, Juan Carlos; Martínez-Martínez, Luis

    2016-10-01

    Cumulative reports on antimicrobial susceptibility tests data are important for selecting empirical treatments, as an educational tool in programs on antimicrobial use, and for establishing breakpoints defining clinical categories. These reports should be based on data validated by clinical microbiologists using diagnostic samples (not surveillance samples). In order to avoid a bias derived from including several isolates obtained from the same patient, it is recommended that, for a defined period, only the first isolate is counted. A minimal number of isolates per species should be presented: a figure of >=30 isolates is statistically acceptable. The report is usually presented in a table format where, for each cell, information on clinically relevant microorganisms-antimicrobial agents is presented. Depending on particular needs, multiple tables showing data related to patients, samples, services or special pathogens can be prepared. Copyright © 2015 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  19. Signal Words

    Science.gov (United States)

    SIGNAL WORDS TOPIC FACT SHEET NPIC fact sheets are designed to answer questions that are commonly asked by the ... making decisions about pesticide use. What are Signal Words? Signal words are found on pesticide product labels, ...

  20. Are low back pain and low physical capacity risk indicators for dropout among recently qualified eldercare workers?

    DEFF Research Database (Denmark)

    Faber, Anne; Giver, Hanne; Strøyer, Jesper

    2010-01-01

    BACKGROUND: A high job turnover and dropout among eldercare workers has led to a significant shortage of qualified manpower in the Danish eldercare sector. OBJECTIVES: The predictive effect of some non-work-related causes for leaving the eldercare sector 2 years after qualification, physical capa...

  1. Dropouts and Compliance in Exercise Interventions Targeting Bone Mineral Density in Adults: A Meta-Analysis of Randomized Controlled Trials

    Directory of Open Access Journals (Sweden)

    George A. Kelley

    2013-01-01

    Full Text Available Background. Dropouts and compliance to exercise interventions targeting bone mineral density (BMD in adults are not well established. The purpose of this study was to address that gap. Methods. Meta-analysis of randomized controlled exercise intervention trials in adults ≥18 years of age. The primary outcomes were dropouts in the exercise and control groups as well as compliance to the exercise interventions. A random-effects model was used to pool results. Moderator analyses were conducted using mixed-effects ANOVA-like models and metaregression. Statistical significance was set at . Results. Thirty-six studies representing 3,297 participants (1,855 exercise, 1,442 control were included. Dropout rates in the exercise and control groups averaged 20.9% (95% CI 16.7%–25.9% and 15.9% (11.8%–21.1% while compliance to exercise was 76.3% (71.7%–80.3%. For both exercise and control groups, greater dropout rates were associated with studies conducted in the USA versus other countries, females versus males, premenopausal versus postmenopausal women, younger versus older participants, longer studies (controls only, and high- versus moderate-intensity training (exercisers only. Greater compliance to exercise was associated with being female, home- or facility-based exercise versus both, and shorter studies. Conclusion. These findings provide important information for researchers and practitioners with respect to exercise programs targeting BMD in adults.

  2. Case report: a successful LipiFlow treatment of a single case of meibomian gland dysfunction and dropout.

    Science.gov (United States)

    Korb, Donald R; Blackie, Caroline A

    2013-05-01

    The aim of this study was to investigate whether a single case of meibomian gland dysfunction (MGD), with significant MG dropout resulting in evaporative dry eye, could be effectively treated with the LipiFlow (a new Food and Drug Administration-approved thermodynamic pulsatile treatment). A 39-year-old white woman experienced severe dry eye symptoms because of MGD with considerable MG dropout resulting in evaporative dry eye. Standardized diagnostic MG expression and meibography led to the tentative diagnosis of nonobvious MGD (only 1 functional MG on each lower lid) and MG dropout (∼50% of the lower lid MGs were missing with the remaining MGs being severely truncated). The patient underwent a single 12-min LipiFlow treatment per eye and returned for follow-up at 1 and 7 months posttreatment. The LipiFlow treatment increased the number of functional lower lid MGs from 1 to 5 glands OD and 1 to 7 glands OS at 1 month with slight regression at 7 months (4 OD and 4 OS); increased fluorescein break-up time from 4 to 7 sec OD and 4 to 9 sec OS at both 1 and 7 months; and decreased symptom scores by approximately 50% at 1 month and approximately 75% at 7 months. These results demonstrate the effectiveness of the LipiFlow in restoring MG function and improving ocular comfort even in this particular case of significant MG dropout and MG truncation.

  3. Thinking, Fast and Slow? Some Field Experiments to Reduce Crime and Dropout in Chicago. NBER Working Paper 21178

    Science.gov (United States)

    Heller, Sara B.; Shah, Anuj K.; Guryan, Jonathan; Ludwig, Jens; Mullainathan, Sendhil; Pollack, Harold A.

    2015-01-01

    We present the results of three large-scale randomized controlled trials (RCTs) carried out in Chicago, testing interventions to reduce crime and dropout by changing the decision-making of economically disadvantaged youth. We study a program called Becoming a Man (BAM), developed by the non-profit Youth Guidance, in two RCTs implemented in 2009-10…

  4. The Peer Relations of Dropouts: A Comparative Study of At-Risk and Not At-Risk Youths.

    Science.gov (United States)

    Ellenbogen, Stephen; Chamberland, Claire

    1997-01-01

    Compared the characteristics of friends, the environments of the friendship network, and the nature of peer relations of students (N=191) at-risk and not at risk of leaving high school. Results indicate that at risk students had more dropout friends, more working friends, fewer school friends, and fewer same-sex friends. (RJM)

  5. Teachers' Views on the Impact of Teacher-Student Relationships on School Dropout: A Bourdieusian Analysis of Misrecognition

    Science.gov (United States)

    Nairz-Wirth, Erna; Feldmann, Klaus

    2017-01-01

    Drawing on Pierre Bourdieu's relational theory this paper shows that many teachers misrecognize the impact of teacher-student relationships on school dropout. The study is based on a series of 60 semi-structured interviews with teachers from Austrian secondary schools. The analysis of the empirical data reveals that many teachers attribute school…

  6. School Dropout Prevention: What Arts-Based Community and Out-of-School-Time Programs Can Contribute

    Science.gov (United States)

    Charmaraman, Linda; Hall, Georgia

    2011-01-01

    Out-of-school-time programs, especially arts-based programs, can be critical players in a community's efforts to prevent school dropout. This research review suggests the following approaches for arts-based programs: (1) recruitment and retention of target populations with multiple risk factors; (2) long-term skill development that engages youth…

  7. Ablation therapy in containing extension of hepatocellular carcinoma: a simulative analysis of dropout from the waiting list for liver transplantation.

    Science.gov (United States)

    Yamashiki, Noriyo; Tateishi, Ryosuke; Yoshida, Haruhiko; Shiina, Shuichiro; Teratani, Takuma; Sato, Shinpei; Mine, Norio; Kondo, Yuji; Kawabe, Takao; Omata, Masao

    2005-05-01

    The dropout from the waiting list for liver transplantation among patients with hepatocellular carcinoma (HCC) is reportedly as high as 12% to 40% per year, mostly due to tumor progression. Considering the scarcity of donor organs, it would be beneficial if we could retain them within the Milan criteria with a bridging therapy. We retrospectively analyzed the prognosis of 288 HCC patients with relatively preserved liver function we treated with ablation therapy between 1997 and 2001, concentrating on whether they subsequently remained in the criteria, and analyzed the risk factors of dropout with Cox proportional hazards model. During a median follow-up period of 39 months (range, 1-86 months), 33 (11%) died without tumor progression, while 85 (30%) dropped out due to tumor progression. The overall dropout rate was 9.0% and 32.8% at 1 and 3 years, respectively, and that due to tumor progression was 6.2% and 23.0%. Cox regression analysis indicated that a high serum level of alpha-fetoprotein or des-gamma-carboxy prothrombin, and a tumor size exceeding 3 cm in diameter affected the dropout due to tumor progression, while low albumin concentration was a risk factor of death independently of tumor progression. In conclusion, local ablation therapy for HCC was effective in containing the tumor progression within the Milan criteria in selected patients.

  8. Perceived Academic Control and Academic Emotions Predict Undergraduate University Student Success: Examining Effects on Dropout Intention and Achievement.

    Science.gov (United States)

    Respondek, Lisa; Seufert, Tina; Stupnisky, Robert; Nett, Ulrike E

    2017-01-01

    The present study addressed concerns over the high risk of university students' academic failure. It examined how perceived academic control and academic emotions predict undergraduate students' academic success, conceptualized as both low dropout intention and high achievement (indicated by GPA). A cross-sectional survey was administered to 883 undergraduate students across all disciplines of a German STEM orientated university. The study additionally compared freshman students (N = 597) vs. second-year students (N = 286). Using structural equation modeling, for the overall sample of undergraduate students we found that perceived academic control positively predicted enjoyment and achievement, as well as negatively predicted boredom and anxiety. The prediction of dropout intention by perceived academic control was fully mediated via anxiety. When taking perceived academic control into account, we found no specific impact of enjoyment or boredom on the intention to dropout and no specific impact of all three academic emotions on achievement. The multi-group analysis showed, however, that perceived academic control, enjoyment, and boredom among second-year students had a direct relationship with dropout intention. A major contribution of the present study was demonstrating the important roles of perceived academic control and anxiety in undergraduate students' academic success. Concerning corresponding institutional support and future research, the results suggested distinguishing incoming from advanced undergraduate students.

  9. Significance of personality disorders in the face of drop-outs from psychiatric hospitalizations. The case of selected psychiatric units.

    Science.gov (United States)

    Biała, Maja; Kiejna, Andrzej

    2017-06-18

    The World Health Organization's estimations indicate that about 50% of patients in well-developed countries may not adhere to long-term therapies. In the field of psychiatry, drop-outs from psychiatric treatment are particularly important. Personality disorders are a significant part of this sphere. The aim of this research was to empirically verify the hypothesis regarding the relation between comorbid personality disorders and drop-outs from treatment among patients of psychiatric wards. This study was a prospective cohort study. 110 patients, hospitalized in 3 different psychiatric wards, were included. Personality disorders were assessed with the Structured Clinical Interview For DSM-IV Personality Disorders (SCID-II). The research was financed by the Polish National Science Center (DEC-2011/01/N/NZ5/05364). The response rate was 89.1%. 72.56% of patients suffered from personality disorders (SCID-II) (among them the most prevalent were: personality disorder - not otherwise specified - 40.7% and borderline personality disorder - 12.38%; 22.95% of patients dropped out from treatment). However, occurrence of personality disorders was not relevant for those drop-outs. On the other hand, relationships at the level of certain criteria of borderline personality disorders and passive-aggressive personality have been revealed. These relationships became stronger when considered from the perspective of differences in the organization of treatment at individual wards. Some personality disorders may play an important role in drop-outs from psychiatric treatment. Presented results require further research.

  10. Perceived Academic Control and Academic Emotions Predict Undergraduate University Student Success: Examining Effects on Dropout Intention and Achievement

    Science.gov (United States)

    Respondek, Lisa; Seufert, Tina; Stupnisky, Robert; Nett, Ulrike E.

    2017-01-01

    The present study addressed concerns over the high risk of university students' academic failure. It examined how perceived academic control and academic emotions predict undergraduate students' academic success, conceptualized as both low dropout intention and high achievement (indicated by GPA). A cross-sectional survey was administered to 883 undergraduate students across all disciplines of a German STEM orientated university. The study additionally compared freshman students (N = 597) vs. second-year students (N = 286). Using structural equation modeling, for the overall sample of undergraduate students we found that perceived academic control positively predicted enjoyment and achievement, as well as negatively predicted boredom and anxiety. The prediction of dropout intention by perceived academic control was fully mediated via anxiety. When taking perceived academic control into account, we found no specific impact of enjoyment or boredom on the intention to dropout and no specific impact of all three academic emotions on achievement. The multi-group analysis showed, however, that perceived academic control, enjoyment, and boredom among second-year students had a direct relationship with dropout intention. A major contribution of the present study was demonstrating the important roles of perceived academic control and anxiety in undergraduate students' academic success. Concerning corresponding institutional support and future research, the results suggested distinguishing incoming from advanced undergraduate students. PMID:28326043

  11. Capacitor-Free, Low Drop-Out Linear Regulator in a 180 nm CMOS for Hearing Aids

    DEFF Research Database (Denmark)

    Yosef-Hay, Yoni; Llimos Muntal, Pere; Larsen, Dennis Øland

    2016-01-01

    This paper presents a capacitor-free low dropout (LDO) linear regulator based on a new dual loop topology. The regulator utilizes the feedback loops to satisfy the challenges for hearing aid devices, which include fast transient performance and small voltage spikes under rapid load-current changes...

  12. Trajectories of Prosocial Behavior and Physical Aggression in Middle Childhood: Links to Adolescent School Dropout and Physical Violence

    Science.gov (United States)

    Kokko, Katja; Tremblay, Richard E.; Lacourse, Eric; Nagin, Daniel S.; Vitaro, Frank

    2006-01-01

    Trajectories of prosocial behavior and physical aggression between 6 and 12 years of age were identified for a sample (N=1,025) of males. The trajectories were then used to predict school dropout and physical violence at age 17. Using a group-based semi-parametric method, two trajectories of prosociality (low and moderate declining) and three…

  13. One Foot out the School Door? Interpreting the Risk for Dropout upon the Transition to Post-Secondary Vocational Education

    Science.gov (United States)

    Elffers, Louise

    2012-01-01

    Many students drop out in the first year after a school transition. Most commonly used indicators of an increased risk for dropout reveal little of the mechanisms that push or pull students out of school. In this study, we look at the association of a set of common risk indicators with students' supportive resources and school experiences upon the…

  14. An Analysis of the Impact of Socio-Economic Disadvantage and School Quality on the Probability of School Dropout

    Science.gov (United States)

    Mahuteau, S.; Mavromaras, K.

    2014-01-01

    This paper combines the Australian Programme for International Student Assessment (PISA) micro-level data with its longitudinal continuation, the Longitudinal Survey of Australian Youth data, to measure the association between individual PISA scores and early school dropouts. We use multilevel modelling to distinguish between student and school…

  15. Theory of Planned Behavior: Sensitivity and Specificity in Predicting Graduation and Drop-Out among College and University Students?

    Science.gov (United States)

    Fichten, Catherine S.; Amsel, Rhonda; Jorgensen, Mary; Nguyen, Mai Nhu; Budd, Jillian; King, Laura; Jorgensen, Shirley; Asuncion, Jennison

    2016-01-01

    We examined sensitivity and specificity when using the three theory of planned behavior (TPB) scales (Perceived Behavioral Control, Subjective Norms, Attitude) to predict graduation and drop-out in a longitudinal study of 252 college and university students with disabilities and in a separate cross-sectional study of a random sample of 1380…

  16. Predicting Dropout from a Residential Programme for Adolescent Sexual Abusers Using Pre-Treatment Variables and Implications for Recidivism

    Science.gov (United States)

    Edwards, Rachel; Beech, Anthony; Bishopp, Daz; Erikson, Matt; Friendship, Caroline; Charlesworth, Lucy

    2005-01-01

    This study addresses the prediction that dropout from a UK specialized residential treatment program for adolescent sexual abusers can be determined from pre-treatment variables. Participants were 49 adolescents aged 12-16 years, who had sexually abused children, peers/adults or both. Of the variables examined, 25 showed a significant association…

  17. Analysis of Factors Causing Poor Passing Rates and High Dropout Rates among Primary School Girls in Malawi

    Science.gov (United States)

    Mzuza, Maureen Kapute; Yudong, Yang; Kapute, Fanuel

    2014-01-01

    Factors that cause poor examination passing rates and high dropout rates among primary school girls in Malawi were analysed. First hand data was collected by conducting a survey in all the three regions of Malawi. The respondents to the questionnaire were girls (402) who are repeating the last class in primary schools (Standard 8), primary school…

  18. Characteristics and Education Outcomes of Utah High School Dropouts Who Re-Enrolled. REL 2017-206

    Science.gov (United States)

    Barrat, Vanessa X.; Berliner, BethAnn

    2016-01-01

    Numerous studies over the past two decades have examined the prevalence, causes, predictors, and prevention of high school dropout, but comparatively little is known about students who drop out and later re-enroll. This study contributes to an emerging body of research on re-enrollees that challenges the perception that when students drop out,…

  19. The Swedish physical activity and fitness cohort born in 1958 - dropout analysis and overview at 36-year follow-up.

    Science.gov (United States)

    Aasa, U; Lundell, S; Barnekow-Bergkvist, M; Jansson, E; Westerståhl, M

    2017-04-01

    The main aim of the Swedish physical activity and fitness cohort study (SPAF-1958) was to describe physical fitness, physical activity, health, and lifestyle across part of the lifespan, and to assess the influences on these factors from the environment, personal factors, and genetics. There is inevitable dropout from longitudinal studies, and it may be systematic. The aim of this first paper of the second follow-up of SPAF-1958 was to provide a dropout analysis to consider to what extent the participants, at 52 years of age, remain a representative sample of the original adolescent study population. Additional aims were to provide an overview of the study protocol and the ongoing study population. Ongoing study participants in SPAF born in 1958 were, at the second follow-up at the age of 52, still representative of the study cohort in terms of sex, adolescent geographical area, upper secondary school program, adolescent body composition, muscular strength, and muscular endurance. However, a higher physical activity and, among women, a higher aerobic capacity in adolescence decreased the risk for dropout. It is important when interpreting results from longitudinal studies to adjust for the systematic dropout that could bias the conclusions drawn from the results. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. Correlates of school dropout and absenteeism among adolescent girls from marginalized community in north Karnataka, south India.

    Science.gov (United States)

    Prakash, Ravi; Beattie, Tara; Javalkar, Prakash; Bhattacharjee, Parinita; Ramanaik, Satyanarayana; Thalinja, Raghavendra; Murthy, Srikanta; Davey, Calum; Blanchard, James; Watts, Charlotte; Collumbien, Martine; Moses, Stephen; Heise, Lori; Isac, Shajy

    2017-12-01

    Secondary education among lower caste adolescent girls living in rural Karnataka, South India, is characterized by high rates of school drop-out and absenteeism. A cross-sectional baseline survey (N=2275) was conducted in 2014 as part of a cluster-randomized control trial among adolescent girls (13-14 year) and their families from marginalized communities in two districts of north Karnataka. Bivariate and multivariate logistic regression models were used. Overall, 8.7% girls reported secondary school dropout and 8.1% reported frequent absenteeism (past month). In adjusted analyses, economic factors (household poverty; girls' work-related migration), social norms and practices (child marriage; value of girls' education), and school-related factors (poor learning environment and bullying/harassment at school) were associated with an increased odds of school dropout and absenteeism. Interventions aiming to increase secondary school retention among marginalized girls may require a multi-level approach, with synergistic components that address social, structural and economic determinants of school absenteeism and dropout. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.