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Sample records for susan stevens hummel

  1. Susan Smith

    African Journals Online (AJOL)

    Owner

    Soveel lesers soveel lokmiddele soveel re- sponse kan gelys word om toegang tot die lees van poësie te registreer. 'n Resep om ge- trou of in ontrou na te volg, bestaan nie. Ge- lukkig nie. Susan Smith se (debuut)bundel lok my helaas nie deur die voorblad as vertrek- punt te neem nie. Aan visuele prikkelkrag gaan.

  2. Steven Moffat and Sue Vertue visits CERN

    CERN Multimedia

    Caraban Gonzalez, Noemi

    2016-01-01

    Steven William Moffat, OBE is a Scottish television writer and producer, known for his work as showrunner, writer and producer of the British television series Doctor Who and Sherlock. Susan "Sue" Nicola Vertue is an English television producer, mainly of comedy shows, including Mr. Bean and Coupling.

  3. SUSANS With Polarized Neutrons.

    Science.gov (United States)

    Wagh, Apoorva G; Rakhecha, Veer Chand; Strobl, Makus; Treimer, Wolfgang

    2005-01-01

    Super Ultra-Small Angle Neutron Scattering (SUSANS) studies over wave vector transfers of 10(-4) nm(-1) to 10(-3) nm(-1) afford information on micrometer-size agglomerates in samples. Using a right-angled magnetic air prism, we have achieved a separation of ≈10 arcsec between ≈2 arcsec wide up- and down-spin peaks of 0.54 nm neutrons. The SUSANS instrument has thus been equipped with the polarized neutron option. The samples are placed in a uniform vertical field of 8.8 × 10(4) A/m (1.1 kOe). Several magnetic alloy ribbon samples broaden the up-spin neutron peak significantly over the ±1.3 × 10(-3) nm(-1) range, while leaving the down-spin peak essentially unaltered. Fourier transforms of these SUSANS spectra corrected for the instrument resolution, yield micrometer-range pair distribution functions for up- and down-spin neutrons as well as the nuclear and magnetic scattering length density distributions in the samples.

  4. Susan Flannery lahkub? / Harro Puusild

    Index Scriptorium Estoniae

    Puusild, Harro

    2008-01-01

    Ameerika teleseriaali "Vaprad ja ilusad" Stephanie Forresteri osatäitja Susan Flannery (1943) on seriaalis mänginud algusest peale s.o. 21 aastat. Lisatud intervjuu näitlejatariga. Sama ka Teleleht nr. 15, lk. 8-9 : ill

  5. Stevens-Johnson Syndrome

    Science.gov (United States)

    ... after blisters form If you have Stevens-Johnson syndrome, several days before the rash develops you may experience: Fever Sore mouth and throat Fatigue Cough Burning eyes When to see a doctor Stevens-Johnson ...

  6. Pinkerton's Creator: Steven Kellogg.

    Science.gov (United States)

    Brodie, Carolyn S.

    2002-01-01

    Describes the life of Steven Kellogg, a children's book illustrator and writer. Includes extension ideas for school library media center activities related to his works and presents a selected annotated bibliography in chronological order, videos, and biographical information. (LRW)

  7. Quality assurance when refitting - SUSAN example

    International Nuclear Information System (INIS)

    Gautier, R.

    1992-01-01

    The most important points of quality assurance for the realisation of the SUSAN project (special independent system for the dissipation of post-decay heat) at the Muehleberg nuclear power station are discussed in this article. The periodic controls and function tests which have been performed since August 1989, confirm the quality of the products used

  8. Design package lazy susan for the fuel retrieval system

    International Nuclear Information System (INIS)

    TEDESCHI, D.J.

    1999-01-01

    This is a design package that contains the details for a Lazy Susan style small tool for the Fuel Retrieval System. The Lazy Susan tool is used to help rotate an MCO Fuel Basket when loading it. This document contains requirements, development design information, tests and test reports that pertain to the production of Lazy Susan small tool

  9. Steven Weinberg visits CERN

    CERN Multimedia

    2009-01-01

    Steven Weinberg visiting the ATLAS cavern accompanied by Peter JenniIt was no surprise that the CERN audience arrived early in the Globe of Science and Innovation for the colloquium on 7 July. Nobel laureate Steven Weinberg is one of the major contributors to the Standard Model of particle physics. He received the Nobel Prize for Physics in 1979 for his work on the unified theory of the electromagnetic and weak interactions, one of the essential pillars of the Standard Model. After lunch at CERN and a visit to ATLAS, Weinberg gave a colloquium on "The Quantum Theory of Fields: Effective or Fundamental" to a packed audience. In his talk, he looked at how the use of quantum field theory in particle physics has fluctuated in popularity since Paul Dirac first introduced the approach to describe the interaction of particles with electromagnetic fields in the late 1920s. In particular, he posed the question: Is quantum field theory fundamental or does it a...

  10. Steven Vogel (1940–2015)

    Indian Academy of Sciences (India)

    IAS Admin

    duced in this issue. Steven Vogel was an eminent American biophysicist. ... as unusual and remarkable as his own work. He pre- .... called Reynolds stress, after the scientist who taught us to think in this ... PES Institute of Technology. Campus.

  11. Psychoanalytic Interpretation of Blueberries by Susan Gibb

    Directory of Open Access Journals (Sweden)

    Maya Zalbidea Paniagua

    2014-06-01

    Full Text Available Blueberries (2009 by Susan Gibb, published in the ELO (Electronic Literature Organization, invites the reader to travel inside the protagonist’s mind to discover real and imaginary experiences examining notions of gender, sex, body and identity of a traumatised woman. This article explores the verbal and visual modes in this digital short fiction following semiotic patterns as well as interpreting the psychological states that are expressed through poetical and technological components. A comparative study of the consequences of trauma in the protagonist will be developed including psychoanalytic theories by Sigmund Freud, Jacques Lacan and the feminist psychoanalysts: Melanie Klein and Bracha Ettinger. The reactions of the protagonist will be studied: loss of reality, hallucinations and Electra Complex, as well as the rise of defence mechanisms and her use of the artistic creativity as a healing therapy. The interactivity of the hypermedia, multiple paths and endings will be analyzed as a literary strategy that increases the reader’s capacity of empathizing with the speaker.

  12. Susan Sontag — A Forgotten Mother?

    Directory of Open Access Journals (Sweden)

    Kludia Ziewiec

    2013-01-01

    Full Text Available The article discusses new and republished translations of Susan Sontag’s work, recently launched by the Karakter publishing house: Regarding the Pan of Others, On Photography, and Against Interpretation and Other Essays. The article focuses on the elements of Sontag’s thought that make her a forgotten mother of feminist and gender theoreticians, as well as such influential critics as Michel Foucault and Roland Barthes. The article points out to continuations of Sontag’s thought in contemporary theoretical and social projects, and to the pertinence of her critical observations on theories based on metaphysics of presence: psychoanalysis, Marxism, or hermeneutics. The article also touches upon history of war photography and related war journalism, and upon the ambivalent quality of imaging of the misery of war. It also present historical and cultural circumstances of the development of Sontag’s thought in the intellectual milieu of New York in the 1960s. The discussion recapitulates the main statements of Sontag’s essays, relating them to a wider theoretical context, which is aimed at a reappraisal of the forgotten intelectual in the history of literature.

  13. LX-04 VIOLENCE MEASUREMENTS- STEVEN TESTS IMPACTED BY PROJECTILES SHOT FROM A HOWITZER GUN

    International Nuclear Information System (INIS)

    Chidester, S K; Vandersall, K S; Switzer, L L; Tarver, C M

    2005-01-01

    Characterization of the reaction violence of LX-04 explosive (85% HMX and 15% Viton A by weight) was obtained from Steven Impact Tests performed above the reaction initiation threshold. A 155 mm Howitzer propellant driven gas gun was used to accelerate the Steven Test projectiles in the range of approximately 170-300 m/s to react (ignite) the LX-04 explosive. Blast overpressure gauges, acoustic microphones, and high-speed photography characterized the level of high explosive reaction violence. A detonation in this velocity range was not observed and when comparing these results (and the Susan test results) with that of other HMX based explosives, LX-04 has a more gradual reaction violence slope as the impact velocity increases. The high binder content (15%) of the LX-04 explosive is believed to be the key factor to the lower level of violence

  14. Meet EPA Scientist Susan Yee, Ph.D.

    Science.gov (United States)

    Susan Yee, Ph.D., is an ecologist at EPA's Gulf Ecology Division. She is working on the Puerto Rico Sustainable Communities program, developing decision support tools to evaluate how alternative decisions impact coastal ecosystem goods and services

  15. James Stevens / James Stevens ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Stevens, James

    2006-01-01

    Inglise disainerist James Stevensist (sünd. 1962) ja tema tegevusest. J. Stevens 2000. a. Amsterdamis tehtud intervjuus koos Jon Bainsi ja Kim Bulliga 1995. a. Londonis avatud Interneti-agentuurist Obsolete, 1996-2000 tegutsenud Interneti-kohvikust Backspace, mittekommertsiaalse juhtmeteta nerworki Consume.net rajamisest Londonis

  16. A conversation with Susan Band Horwitz.

    Science.gov (United States)

    Horwitz, Susan Band; Goldman, I David

    2015-01-01

    Susan Band Horwitz is a Distinguished Professor and holds the Falkenstein Chair in Cancer Research at Albert Einstein College of Medicine in New York. She is co-chair of the Department of Molecular Pharmacology and associate director for therapeutics at the Albert Einstein Cancer Center. After graduating from Bryn Mawr College, Dr. Horwitz received her PhD in biochemistry from Brandeis University. She has had a continuing interest in natural products as a source of new drugs for the treatment of cancer. Her most seminal research contribution has been in the development of Taxol(®). Dr. Horwitz and her colleagues made the discovery that Taxol had a unique mechanism of action and suggested that it was a prototype for a new class of antitumor drugs. Although Taxol was an antimitotic agent blocking cells in the metaphase stage of the cell cycle, Dr. Horwitz recognized that Taxol was blocking mitosis in a way different from that of other known agents. Her group demonstrated that the binding site for Taxol was on the β-tubulin subunit. The interaction of Taxol with the β-tubulin subunit resulted in stabilized microtubules, essentially paralyzing the cytoskeleton, thereby preventing cell division. Dr. Horwitz served as president (2002-2003) of the American Association for Cancer Research (AACR). She is a member of the National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, and the American Philosophical Society. She has received numerous honors and awards, including the C. Chester Stock Award from Memorial Sloan Kettering Cancer Center, the Warren Alpert Foundation Prize from Harvard Medical School, the Bristol-Myers Squibb Award for Distinguished Achievement in Cancer Research, the American Cancer Society's Medal of Honor, and the AACR Award for Lifetime Achievement in Cancer Research. The following interview was conducted on January 23, 2014.

  17. Steven Hawking with Robert Aymar

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Steven Hawking is seen meeting with CERN's Director-General, Robert Aymar. Hawking visited CERN between 24 September and 1 October 2006. During his stay he gave two lectures and toured the LHC, which may provide insights into Hawking's most famous area of study, black holes.

  18. Susan swan and the female grotesque Susan swan and the female grotesque

    Directory of Open Access Journals (Sweden)

    Suzana Bornéo Funck

    2008-04-01

    Full Text Available Introduced to readers as “the tallest woman freelance writer in Canada”, Susan Swan belongs to a generation of writers whose experimental, innovative fiction has proved vital in the contemporary project of de/re/constructing narrative practice. Her 1983 novel The Biggest Modern Woman of the World constitutes an excellent example of what critic Linda Hutcheon has termed “historiographic metafiction”—”fiction that is intensely, self-reflexively art, but is also grounded in historical, social, and political realities” (Canadian 13. As a conscious engagement with social and historical contexts, such fiction aims at destabilizing and subverting accepted patterns of belief by reconceptualizing and narrating possible subjectivities. By means of intertextuality, especially parody, it engages in an ideological critique in terms of both sexual and national politics. Introduced to readers as “the tallest woman freelance writer in Canada”, Susan Swan belongs to a generation of writers whose experimental, innovative fiction has proved vital in the contemporary project of de/re/constructing narrative practice. Her 1983 novel The Biggest Modern Woman of the World constitutes an excellent example of what critic Linda Hutcheon has termed “historiographic metafiction”—”fiction that is intensely, self-reflexively art, but is also grounded in historical, social, and political realities” (Canadian 13. As a conscious engagement with social and historical contexts, such fiction aims at destabilizing and subverting accepted patterns of belief by reconceptualizing and narrating possible subjectivities. By means of intertextuality, especially parody, it engages in an ideological critique in terms of both sexual and national politics.

  19. International Literacy Crusader: An Interview with Susan Mandel Glazer

    Science.gov (United States)

    Ambrose, Valerie K.

    2011-01-01

    This article presents an interview with Susan Mandel Glazer, past president of both the International Reading Association and the College Reading Association. Dr. Glazer received her doctorate in education from the University of Pennsylvania and her master of arts from New York University. Her most recent books are "Beyond the Looking Glass:…

  20. Infrared image background modeling based on improved Susan filtering

    Science.gov (United States)

    Yuehua, Xia

    2018-02-01

    When SUSAN filter is used to model the infrared image, the Gaussian filter lacks the ability of direction filtering. After filtering, the edge information of the image cannot be preserved well, so that there are a lot of edge singular points in the difference graph, increase the difficulties of target detection. To solve the above problems, the anisotropy algorithm is introduced in this paper, and the anisotropic Gauss filter is used instead of the Gauss filter in the SUSAN filter operator. Firstly, using anisotropic gradient operator to calculate a point of image's horizontal and vertical gradient, to determine the long axis direction of the filter; Secondly, use the local area of the point and the neighborhood smoothness to calculate the filter length and short axis variance; And then calculate the first-order norm of the difference between the local area of the point's gray-scale and mean, to determine the threshold of the SUSAN filter; Finally, the built SUSAN filter is used to convolution the image to obtain the background image, at the same time, the difference between the background image and the original image is obtained. The experimental results show that the background modeling effect of infrared image is evaluated by Mean Squared Error (MSE), Structural Similarity (SSIM) and local Signal-to-noise Ratio Gain (GSNR). Compared with the traditional filtering algorithm, the improved SUSAN filter has achieved better background modeling effect, which can effectively preserve the edge information in the image, and the dim small target is effectively enhanced in the difference graph, which greatly reduces the false alarm rate of the image.

  1. Resurrecting Absence: Iconic Ghosts in the Poetry of Susan Howe

    Directory of Open Access Journals (Sweden)

    Jessica Wilkinson

    2011-04-01

    Full Text Available The article focuses on the opinions of Susan Howe in her book A Bibliography of the King's Book, Or Eikon Basilike. It cites that Howe's work reflects her evocative visual and verbal landscapes as well as her enthusiasm of leading readers to the obscurities of textual and historical respresentation. It also discusses the strange tyrannical martyrdom of King Charles the First and his publication as well as her understanding of Edward Almack's bibliographical project.

  2. Magnuson-Stevens Fishery Conservation Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Magnuson-Stevens Fishery Conservation and Management Act (MSA) is the primary law governing marine fisheries management in U.S. federal waters. It has since been...

  3. Parallax adjustment algorithm based on Susan-Zernike moments

    Science.gov (United States)

    Deng, Yan; Zhang, Kun; Shen, Xiaoqin; Zhang, Huiyun

    2018-02-01

    Precise parallax detection through definition evaluation and the adjustment of the assembly position of the objective lens or the reticle are important means of eliminating the parallax of the telescope system, so that the imaging screen and the reticle are clearly focused at the same time. An adaptive definition evaluation function based on Susan-Zernike moments is proposed. First, the image is preprocessed by the Susan operator to find the potential boundary edge. Then, the Zernike moments operator is used to determine the exact region of the reticle line with sub-pixel accuracy. The image definition is evaluated only in this related area. The evaluation function consists of the gradient difference calculated by the Zernike moments operator. By adjusting the assembly position of the objective lens, the imaging screen and the reticle will be simultaneously in the state of maximum definition, so the parallax can be eliminated. The experimental results show that the definition evaluation function proposed in this paper has the advantages of good focusing performance, strong anti-interference ability compared with the other commonly used definition evaluation functions.

  4. Stevens-Johnson syndrome after radiotherapy

    International Nuclear Information System (INIS)

    Howell, W.R.; Knight, A.L.; Scruggs, H.J.

    1990-01-01

    We have reported a case of classic Stevens-Johnson syndrome in association with treatment using a cobalt radiation therapy unit. Previous reports of such an association have been extremely rare. At the time of the reaction, the patient's only medications were methyldopa and trichlormethiazide. Other drugs in the thiazide class have been associated with such a reaction. We feel this is an unlikely association in our patient, however, because she had been on trichlormethiazide for a number of years. This report suggests the role of radiotherapy as a rare cause of Stevens-Johnson syndrome. 14 references

  5. Practitioner Profile: An Interview with Susan Bross, AFC®

    Directory of Open Access Journals (Sweden)

    Susan Bross

    2011-04-01

    Full Text Available

    Susan Bross is a nationally accredited financial counselor who established her private practice in 1992. She currently lives in San Rafael, California. She brings a multi-faceted background and a combination of skills to her work. As a financial counselor, she works with individuals, couples, and entrepreneurs throughout the nation to help clients develop a practical and emotionally healthy relationship with money. When asked, she will tell you that she is passionate about her work because it mirrors her own hard-won path with money. Readers of the Journal will find Ms. Bross’s approach to financial therapy inspiring. She teaches simple tools for effortless and sustainable cash flow and money management. She also guides her clients to balanced attitudes and beliefs about money and success.

  6. [The Durkheim Test. Remarks on Susan Leigh Star's Boundary Objects].

    Science.gov (United States)

    Gießmann, Sebastian

    2015-09-01

    The article reconstructs Susan Leigh Star's conceptual work on the notion of 'boundary objects'. It traces the emergence of the concept, beginning with her PhD thesis and its publication as Regions of the Mind in 1989. 'Boundary objects' attempt to represent the distributed, multifold nature of scientific work and its mediations between different 'social worlds'. Being addressed to several 'communities of practice', the term responded to questions from Distributed Artificial Intelligence in Computer Science, Workplace Studies and Computer Supported Cooperative Work (CSCW), and microhistorical approaches inside the growing Science and Technology Studies. Yet the interdisciplinary character and interpretive flexibility of Star’s invention has rarely been noticed as a conceptual tool for media theory. I therefore propose to reconsider Star's 'Durkheim test' for sociotechnical media practices.

  7. Steven Spielberg hädas Peeter Paaniga / Timo Diener

    Index Scriptorium Estoniae

    Diener, Timo

    2004-01-01

    Steven Spielbergi raskused J.M. Barrie "Peeter Paani" ekraniseerimisel, tulemuseks mängufilm "Hook" : Ameerika Ühendriigid 1991. Järgneb 16. aug. 2004, lk. 38 pealkirja all "Rahulolematu Steven Spielberg"

  8. Stevens Johnsons syndrom og toksisk epidermal nekrolyse

    DEFF Research Database (Denmark)

    Kaur-Knudsen, Diljit; Zachariae, Claus; Thomsen, Simon Francis

    2013-01-01

    Stevens-Johnson syndrome and toxic epidermal necrolysis are acute mucocutaneous diseases primarily due to drug intake. The diseases are characterised by the separation of epidermis from dermis which can be life-threatening. Mortality is often caused by sepsis and multiple organ failure. The most...

  9. Thinking about rumination: the scholarly contributions and intellectual legacy of Susan Nolen-Hoeksema.

    Science.gov (United States)

    Lyubomirsky, Sonja; Layous, Kristin; Chancellor, Joseph; Nelson, S Katherine

    2015-01-01

    Our article reviews and celebrates Susan Nolen-Hoeksema's remarkable contributions to psychological and clinical science, focusing on her vast body of theoretical and empirical work and her influence on colleagues and students. Susan spent her career trying to understand how and why a style of regulating emotions called rumination increases vulnerability to depression and exacerbates and perpetuates negative moods. More broadly, we describe research by Susan and her colleagues on the predictors of depression in childhood and adolescence; gender differences in depression and rumination in adolescence and adulthood; roots, correlates, and adverse consequences of ruminative response styles; and rumination as a transdiagnostic risk factor for not only depression but also a host of psychological disorders, including anxiety, substance abuse, and eating disorders. Susan's intellectual legacy is evident in her impressive publication and citation record, the clinical applications of her work, and the flourishing careers of the students she mentored.

  10. Stevens-Johnson Syndrome After Armodafinil Use.

    Science.gov (United States)

    Holfinger, Steven; Roy, Asim; Schmidt, Markus

    2018-05-15

    We present the case of a 21-year-old woman in whom Stevens-Johnson syndrome (SJS) developed after initiation of armodafinil. Although this rare and life-threatening reaction is listed on armodafinil's label, no cases have been reported in the literature. This case, in addition to an update of the drug's label after post-marketing research, both support the link between armodafinil and SJS. Providers should maintain a high clinical suspicion for SJS when starting therapy to minimize associated morbidity and mortality by discontinuing armodafinil at the onset of first symptoms. © 2018 American Academy of Sleep Medicine.

  11. Steven Vogel was an eminent American biophysicist. He made ...

    Indian Academy of Sciences (India)

    Keywords. Steven Vogel, biomechanics, Péclet number, diffusion, advection, transport. Abstract. Steven Vogel was a pinoneer in applying principles of mechanics to diverse living systems. This article first provides a brief overview of his career. It then reviews the concepts of P´eclet number and Reynolds number which are ...

  12. Co-amoxiclav-induced Stevens Johnson Syndrome in a child ...

    African Journals Online (AJOL)

    Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome in children.

  13. Kitybė Susan Hill novelėje ,,The Woman in Black“

    OpenAIRE

    Kučinskaitė, Martyna

    2016-01-01

    Otherness in the Novella by Susan Hill “The Woman in Black” The present BA paper considers the representation of otherness in Susan Hill’s horror novella The Woman in Black (1983). The novella’s story is set in the Victorian England where the main concerns are the ghost of Jennet Humfrye who haunts the village, Crythin Gifford, and the haunted Eel Marsh House. Whenever she is seen by someone in the village, or in the house she haunts, a child dies under mysterious circumstances. The present p...

  14. Binding in the Lazy Susan of the 1 MW TRIGA at the Centro Nuclear de Mexico

    International Nuclear Information System (INIS)

    Sanchez, J.; Mulas, P.; Mariano, G.; Hernandez, R.

    1974-01-01

    Problems with the original Lazy Susan were reported in a previous conference, where the procedure followed for its removal was described. A new Lazy Susan was supplied by the fabricant and it was judged convenient to perform an out-of-core test of the dispositive. A rig was built to produce temperature gradients similar to the ones encountered in the operation at high power levels. After a temperature difference (estimated between 130 o C and 170 o C) between the rotating part and the outside surface was established, the Lazy Susan started to bind. This was reported to the fabricant and it was concluded that a new design was needed and since it would take at least two years before the new unit could be acquired, it was decided to install the Lazy Susan recently supplied. The unit now rotates for approximately 20 minutes when the reactor is operating at 1 MW and then binds. At lower power levels it is operative for longer periods of time. (author)

  15. Teaching Students About Stereotypes, Prejudice, and Discrimination: An Interview with Susan Fiske

    Science.gov (United States)

    Hackney, Amy

    2005-01-01

    Susan T. Fiske is professor of psychology, Princeton University (PhD, Harvard University; honorary doctorate, Universite Catholique de Louvain-la-Neuve, Belgium). She wrote Social Cognition (with Taylor) on how people make sense of each other. Currently, she investigates emotional prejudices (pity, contempt, envy, and pride) at cultural,…

  16. Binding in the Lazy Susan of the 1 MW TRIGA at the Centro Nuclear de Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, J; Mulas, P; Mariano, G; Hernandez, R [Instituto Nacional de Energia Nuclear (Mexico)

    1974-07-01

    Problems with the original Lazy Susan were reported in a previous conference, where the procedure followed for its removal was described. A new Lazy Susan was supplied by the fabricant and it was judged convenient to perform an out-of-core test of the dispositive. A rig was built to produce temperature gradients similar to the ones encountered in the operation at high power levels. After a temperature difference (estimated between 130{sup o}C and 170{sup o}C) between the rotating part and the outside surface was established, the Lazy Susan started to bind. This was reported to the fabricant and it was concluded that a new design was needed and since it would take at least two years before the new unit could be acquired, it was decided to install the Lazy Susan recently supplied. The unit now rotates for approximately 20 minutes when the reactor is operating at 1 MW and then binds. At lower power levels it is operative for longer periods of time. (author)

  17. Re-Establishing Social Studies as a Core Subject: An Interview with Susan Griffin

    Science.gov (United States)

    Griffin, Susan

    2014-01-01

    NCSS Executive Director Susan Griffin was chair of the Task Force of Professional Organizations that worked with the Social Studies Assessment, Curriculum, and Instruction Collaborative (SSACI) of the Council of Chief State School Officers to initiate and guide the development of the "College, Career and Civic Life (C3) Framework for Social…

  18. Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis ...

    African Journals Online (AJOL)

    REVIEW. Introduction. Stevens-Johnson syndrome (SJS) and toxic epidermal ... that affect the skin and mucous membranes. ... Open Access article distributed under the terms of the .... pathogenic components are removed from plasma. The.

  19. Two autographs: Cecile Dewitt and Robert Hawking (for Steven Hawking)

    Science.gov (United States)

    Gaina, Alex

    2007-12-01

    Two autographs given to author by professor Cecile Dewitt and Robert Hawking (the son of Steven Hawking for his father) in 1987 during the Quantum Gravity Seminar in Moscow are presented. The first was given during a visit to Physical Institute of the Academy of sciences of the USSR, where a seminar held in the Theoretical department. the second was given during a lunch with Steven Hawking, Andrei Linde and Robert Hawking at the 2-nd floor of the Conference floor.

  20. Susan And Lucy: Two Outstanding Heroines Of Alan Ayckbourn / Susan ve Lucy: Alan Ayckbourn’un İki Sıradışı Kadın-Kahramanı

    OpenAIRE

    Parlak, Erdinç

    2012-01-01

    Alan Ayckbourn (1939-     ) has an important place among the twentieth century British playwrights. The playwright handles some present-day social problems such as insensitiveness, lack of communication, lack of love, collision, alienation, moral degeneration especially around his heroines. Susan, the protagonist of Woman in Mind, and Lucy, the little heroine in Invisible Friends, are among the outstanding heroines of the playwright. The life experiences of Susan and Lucy reflected from the s...

  1. Detection algorithm of infrared small target based on improved SUSAN operator

    Science.gov (United States)

    Liu, Xingmiao; Wang, Shicheng; Zhao, Jing

    2010-10-01

    The methods of detecting small moving targets in infrared image sequences that contain moving nuisance objects and background noise is analyzed in this paper. A novel infrared small target detection algorithm based on improved SUSAN operator is put forward. The algorithm selects double templates for the infrared small target detection: one size is greater than the small target point size and another size is equal to the small target point size. First, the algorithm uses the big template to calculate the USAN of each pixel in the image and detect the small target, the edge of the image and isolated noise pixels; Then the algorithm uses the another template to calculate the USAN of pixels detected in the first step and improves the principles of SUSAN algorithm based on the characteristics of the small target so that the algorithm can only detect small targets and don't sensitive to the edge pixels of the image and isolated noise pixels. So the interference of the edge of the image and isolate noise points are removed and the candidate target points can be identified; At last, the target is detected by utilizing the continuity and consistency of target movement. The experimental results indicate that the improved SUSAN detection algorithm can quickly and effectively detect the infrared small targets.

  2. Cefepime Associated With Phenytoin Induced Stevens-Johnson Syndrome.

    Science.gov (United States)

    Marco-Del Río, José; Domingo-Chiva, Esther; Cuesta-Montero, Pablo; Valladolid-Walsh, Ana; García-Martínez, Eva María

    We describe a recent case of Stevens-Johnson Syndrome. A 49-year-old man was admitted to the Intensive Care Unit of an Anaesthesia and Resuscitation Department because of a Fournier gangrene that derived in a sepsis, ventilator-associated pneumonia, and renal failure. He was under treatment with cefepime and suffered a generalized status epilepticus, so started treatment with phenytoin. The next day he developed a "maculous cutaneous eruption in trunk and lower limbs" compatible with a Stevens-Johnson Syndrome. Stevens-Johnson Syndrome is a very severe and potentially fatal multiorganic disease, especially when present in critically ill patients, with a strong drug-related etiology, especially with antiepileptic drugs.

  3. Tables of Products of Tensor Operators and Stevens Operators

    DEFF Research Database (Denmark)

    Lindgård, Per-Anker

    1975-01-01

    Numerical tables of products of tensor (Racah) operators, Rl,m(J), and Stevens operators Olm(J), working within a J-multiplet are given as a function of X=J(J+1). Examples of the use of the tables, such as the calculation of commutation relations and thermal averages are given.......Numerical tables of products of tensor (Racah) operators, Rl,m(J), and Stevens operators Olm(J), working within a J-multiplet are given as a function of X=J(J+1). Examples of the use of the tables, such as the calculation of commutation relations and thermal averages are given....

  4. Hummel's Digital Transformation Toward Omnichannel Retailing

    DEFF Research Database (Denmark)

    Hansen, Rina; Sia, Siew Kien

    2015-01-01

    With the phenomenal growth of mobile and social media, many organizations are realizing they need an online presence to reach out to digitally savvy customers. But delivering a seamless customer experience across various online and offline channels is increasingly challenging. This article descri...

  5. Justice John Paul Stevens and the Erotic Boomerang.

    Science.gov (United States)

    Lieberman, Marc

    Justice John Paul Stevens of the United States Supreme Court has ruled on obscenity cases in seven instances since his appointment. His rulings reveal that he regards obscenity as a nuisance rather than as a danger threatening to undermine the nation's morality, that he supports a nationwide standard to adjudicate obscenity cases, and that he…

  6. Risk of nevirapine-associated Stevens-Johnson syndrome among ...

    African Journals Online (AJOL)

    Background. Stevens-Johnson syndrome (SJS) is an acute life-threatening condition often elicited by drugs. The government's indecisiveness in deciding to stop the use of nevirapine (NVP) in HIV-infected pregnant women owing to the increase of SJS among this population group in South Africa prompted this investigation ...

  7. Gamification is broken. An interview with Steven Poole

    Directory of Open Access Journals (Sweden)

    Marco Benoit Carbone

    2012-05-01

    Full Text Available Steven Poole is the author of Trigger Happy (2000. New York, NY: Arcade Publish, Unspeak (2006. New York, NY: Grove Press, and You Aren’t What You Eat (2012. In press. He has written extensively on books, culture, and videogames for The Guardian and other publications.

  8. Award for Distinguished Scientific Contributions: Steven F. Maier

    Science.gov (United States)

    American Psychologist, 2009

    2009-01-01

    Steven F. Maier, winner of the Award for Distinguished Scientific Contributions, is cited for his work in the fields of learned helplessness; cytokines, depressed mood, and cognitive interference; and the brain structures that produce and counteract learned helplessness. In addition to the citation, a biography and selected bibliography of Maier's…

  9. Holokaust Steven Spielbergi pilgu läbi / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2000-01-01

    Oscari võitnud dokumentaalfilm "Need viimased päevad" ("The Last Days") : režissöör James Moll : Tootja Steven Spielbergi loodud Survivors of the Shoah Visual History Foundation : Ameerika Ühendriigid 1999. Filmi esitlusest Eesti Vabariigi Välisministeeriumis

  10. Steven Vogel was an eminent American biophysicist. He made ...

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... Steven Vogel was a pinoneer in applying principles of mechanics to diverse living systems. This article first provides a brief overview of his career. It then reviews the concepts of P´eclet number and Reynolds number which are helpful in appreciating the Classics article by Vogel reproduced in this issue.

  11. Born To Draw: A Profile of Steven Kellogg.

    Science.gov (United States)

    Elleman, Barbara

    2001-01-01

    Presents a profile of Steven Kellogg, an illustrator of children's books. Gives an overview of his career discussing how he got started and broke into the scene. Describes some of the books he has illustrated and relates his experiences with those books. (SG)

  12. Steven MacCall: Winner of LJ's 2010 Teaching Award

    Science.gov (United States)

    Berry, John N., III

    2010-01-01

    This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

  13. Fatal nevirapine-induced Stevens- Johnson syndrome with HIV ...

    African Journals Online (AJOL)

    2014-06-01

    Jun 1, 2014 ... of Stevens-Johnson syndrome highlights the dilemmas and complications that may arise when prescribing multiple medications in HIV-associated ... HIV enters the central nervous system early in the course of HIV ... Affected individuals with SJS/TEN are genetically predisposed to developing severe ...

  14. A New Approach: The Feminist Musicology Studies of Susan McClary and Marcia J. Citron

    Directory of Open Access Journals (Sweden)

    Kimberly Reitsma

    2014-06-01

    Full Text Available One of the currently prevalent analytic approaches in academia is feminist theory and criticism. Its combination with musicology has influenced the field for the past four decades. The goal of the new approach, loosely termed “feminist musicology,” has been to discover, analyze, discuss, and promote the representation of women and the “feminine” essence in various disciplines of music. Today, feminist musicology is highly researched, published in books and journals, and presented as scholarly papers at various musicological conferences around the world. This new approach introduces the ideologies of feminism to the study of music. Susan McClary and Marcia J. Citron are two musicologists who were influenced by these ideologies and have guided the musicological world in this direction of feminist musicology. Both have made serious contributions to the emerging field of feminist musicology. Both researched the ideas of gender musical construction within musical narratives, music as a gendered discourse, and historical and social factors that affected women in music. Although they have met with considerable resistance, Susan McClary and Marcia J. Citron have significantly expanded the scope of musicology through their application of feminist theory.

  15. Stevens-Johnson syndrome associated with antimicrobial agent

    Directory of Open Access Journals (Sweden)

    Ivo Cavalcanti Pita Neto

    2008-01-01

    Full Text Available Among the severe reactions to medications, immune-mediated Mucocutaneous Disorders are widely represented. Steven-Johnson’s syndrome, or great multiform erythema, appears as a systemic disturbance, involving the skin and mucous membranes, and is related to several factors, such as, viral or bacterial infections and particularly the administration of medicines, in general painkillers and antibiotics. The objective of this article is report the onset of ulcerative vesicle –blister lesions in the regions of the lips, gums, tongue and genital mucosa membrane in a 26 year-old patient, a leukoderm man, being treated with sulfamethoxazole trimethoprim for a respiratory infection, after being diagnosed as having the Steven-Johnson syndrome. SSJ1 558187121279.

  16. (REREADING INDEX CARDS: THE ARCHIVIST AS INTERPRETER IN SUSAN PUI SAN LOK'S 'NEWS'

    Directory of Open Access Journals (Sweden)

    Sandra Camacho

    2018-01-01

    Full Text Available Looking at susan pui san lok's projects News (2005 and RoCH (2013, this paper contemplates the notions put forward by Michel-Rolph Trouillot and Jacques Derrida on the power of archivists, not solely as guardians of documents but also as their interpreters. Taking into consideration that photographic and moving image archives present unique difficulties in their cataloguing processes, I examine silences that might be generated by a thematic classification that is not impervious to archivists' biases. Moreover, I consider if the silences created by manual processes of classification and retrieval might be surpassed through digital technologies, or if it is possible that new technologies simply create different types of silencing.

  17. Intermittent large amplitude internal waves observed in Port Susan, Puget Sound

    Science.gov (United States)

    Harris, J. C.; Decker, L.

    2017-07-01

    A previously unreported internal tidal bore, which evolves into solitary internal wave packets, was observed in Port Susan, Puget Sound, and the timing, speed, and amplitude of the waves were measured by CTD and visual observation. Acoustic Doppler current profiler (ADCP) measurements were attempted, but unsuccessful. The waves appear to be generated with the ebb flow along the tidal flats of the Stillaguamish River, and the speed and width of the resulting waves can be predicted from second-order KdV theory. Their eventual dissipation may contribute significantly to surface mixing locally, particularly in comparison with the local dissipation due to the tides. Visually the waves appear in fair weather as a strong foam front, which is less visible the farther they propagate.

  18. An Interview with Susan Conners: An Educator's Observations about Living with and Educating Others about Tourette's Syndrome.

    Science.gov (United States)

    Chamberlain, Steven P.

    2003-01-01

    In this interview with Susan Conners, a middle school French teacher who has lived with Tourette syndrome (TS) since age 6, she discusses her lack of diagnosis until age 36, difficulties in school, why TS should be listed under "Other Health Impaired" in federal legislation, characteristics of TS, and interventions. (Contains…

  19. Lesson Plans for "Not for Ourselves Alone: The Story of Elizabeth Cady Stanton and Susan B. Anthony."

    Science.gov (United States)

    Prososki, Lisa; Krouse, Judith; Harper, Judith E.

    These lesson plans for high school students were developed to accompany the documentary film by Ken Burns and Paul Barnes which tells the story of Elizabeth Cady Stanton and Susan B. Anthony and their lifelong fight for women's rights. In the lessons students write editorials about women's rights around the world today, interview senior citizens…

  20. "I Am Not a Fairy Tale": Contextualizing Sioux Spirituality and Story Traditions in Susan Power's "The Grass Dancer"

    Science.gov (United States)

    Diana, Vanessa Holford

    2009-01-01

    Standing Rock Sioux writer Susan Power's best-selling novel "The Grass Dancer" (1994) includes depictions of the supernatural and spiritual that do not conform to the Judeo-Christian or, in some cases, the atheist or rationalist worldviews of many readers. Power writes of ghost characters and haunted places, communication between the living and…

  1. 78 FR 75676 - Mark W. Dobronski and Susan K. Dobronski-Acquisition of Control Exemption-Adrian & Blissfield...

    Science.gov (United States)

    2013-12-12

    ... Ferrovia, L.L.C. (Ferrovia), also a noncarrier and a limited liability company, which, until very recently... and Susan K. Dobronski--Acquisition of Control Exemption--Adrian & Blissfield Rail Road Company, Charlotte Southern Railroad Company, Detroit Connecting Railroad Company, Lapeer Industrial Railroad Company...

  2. HLA-B Sequencing in Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

    Science.gov (United States)

    2017-03-03

    Stevens -Johnson Syndrome and Toxic Epidermal Necrolysis Brittany L. Lenz, MD, Andrew T. Patterson, MD, Amanda J . Laska, MD, Patrick J . Brown, MD, and...59 MDW/SGVU SUBJECT: Professional Presentation Approval 8 DEC 2016 1. Your paper, entitled HLA-B Sequencing in Patients with Stevens -Johnson...PATIENTS WITH STEVENS -JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROL YSIS 2. FUNDING RECEIVED FOR THIS STUDY? DYES rgj NO FUNDING SOURCE: I I 3. IS THIS

  3. Musical Metaphors in the Poetry of Wallace Stevens

    Directory of Open Access Journals (Sweden)

    Victor Kennedy

    2016-06-01

    Full Text Available Wallace Stevens’s “The Man with the Blue Guitar” (1937 is widely recognized as one of the most important and influential poems of the 20th century. Inspired by Picasso’s painting The Old Guitarist, the poem in turn inspired Michael Tippett’s sonata for solo guitar, “The Blue Guitar” (Tippett 1983 and David Hockney’s The Blue Guitar: Etchings by David Hockney who was inspired by Wallace Stevens who was inspired by Pablo Picasso (Hockney and Stevens 1977. Central to “The Man with the Blue Guitar,” the metaphor of the musical instrument as a transformational symbol of the imagination is common in Stevens’s poems. The structure of “The Man with the Blue Guitar,” according to J. Hillis Miller, is the structure of stream-of-consciousness. Stevens’s poem creates what has been called “the deconstructed moment in modern poetry,” “an attempt to project a spatialized time that can be viewed from the privileged position of a timeless, static moment capable of encompassing a life at a glance” (Jackson 1982. This consciousness, which Derrida refers to as the “trace,” Stevens calls “the evasive movement of language.” The trace is the perception of the absence of meaning after the word or perception has passed, the glimpse of a hidden meaning that immediately vanishes. Stevens’s poem influenced not only other poets, artists and composers; references to and echoes of his ideas and techniques can be seen in popular music and culture well into the 21st century.

  4. Stevens-Johnson syndrome associated with Malarone antimalarial prophylaxis.

    Science.gov (United States)

    Emberger, Michael; Lechner, Arno Michael; Zelger, Bernhard

    2003-07-01

    To the best of our knowledge, Stevens-Johnson syndrome (SJS) has not been reported previously as an adverse reaction to Malarone, which is a combination of atovaquone and proguanil hydrochloride used for antimalarial prophylaxis and therapy. We describe a 65-year-old patient who had SJS with typical clinical and histopathological findings associated with the use of Malarone prophylaxis for malaria. This report should alert physicians to this severe cutaneous reaction, and Malarone should be added to the list of drugs that can potentially cause SJS.

  5. 'Speaking Kleinian': Susan Isaacs as Ursula Wise and the Inter-War Popularisation of Psychoanalysis.

    Science.gov (United States)

    Shapira, Michal

    2017-10-01

    How did the complex concepts of psychoanalysis become popular in early twentieth-century Britain? This article examines the contribution of educator and psychoanalyst Susan Isaacs (1885-1948) to this process, as well as her role as a female expert in the intellectual and medical history of this period. Isaacs was one of the most influential British psychologists of the inter-war era, yet historical research on her work is still limited. The article focuses on her writing as 'Ursula Wise', answering the questions of parents and nursery nurses in the popular journal Nursery World, from 1929 to 1936. Researched in depth for the first time, Isaacs' important magazine columns reveal that her writing was instrumental in disseminating the work of psychoanalyst Melanie Klein in Britain. Moreover, Isaacs' powerful rebuttals to behaviourist, disciplinarian parenting methods helped shift the focus of caregivers to the child's perspective, encouraging them to acknowledge children as independent subjects and future democratic citizens. Like other early psychoanalysts, Isaacs was not an elitist; she was in fact committed to disseminating her ideas as broadly as possible. Isaacs taught British parents and child caregivers to 'speak Kleinian', translating Klein's intellectual ideas into ordinary language and thus enabling their swift integration into popular discourse.

  6. A Journey, the Pain of Others, and Historical Experience: Susan Silas

    Directory of Open Access Journals (Sweden)

    Sendyka, Roma

    2014-12-01

    Full Text Available The author interprets Susan Silas' Helmbrechts walk (1998-2003, a unique series of forty-five photographs and supplementing visual and textual materials collected during the walk along the route of two hundred and twenty-five miles. The walk repeats the route which in 1945 had to undertake women prisoners from the concentration camp in Helmbrechts near Flossenbürg in their death march to Prachatice in Czech Republic. The pictures Silas takes, the people she meets, and finally the trees, the very materiality of the road become the factors of creating her own, individual memory of the event from the past. Silas selects an object from "the margins of the Holocaust" – a forgotten event that she re-presents by reacting to contemporary objects placed along the route of the event. Silas' work offers an opportunity to critically review the concept of memory landscapes (where is memory located in a landscape? and the phenomenon of dark tourism (is following in the footsteps of the prisoners a kind of pilgrimage, tourism, or therapy?. Silas problematises the question of memory, as well as examines different kinds of non-memory. Her camera is directed at locations that can be termed "the non-sites of memory."

  7. The haunting of Susan Lay: servants and mistresses in seventeenth-century England.

    Science.gov (United States)

    Gowing, Laura

    2002-01-01

    At Easter 1650, Susan Lay, a servant in an Essex alehouse, saw the ghost of her mistress, who had been buried three days before. This article explores the history that lay behind her experience: of sexual relationships with both her master and his son, the births and deaths of two bastard children, and beneath it all, a relationship of antagonism, competition, and intimacy with her mistress. It uses this and other legal records to examine the relationship between women in early modern households, arguing that, while antagonisms between women are typically part of effective patriarchies, the domestic life and social structures of mid seventeenth-century England bound servants and mistresses peculiarly tightly together, giving servants licence to dream of replacing their mistresses and mistresses cause to feel threatened by their servants, and making the competitive relations between women functional to patriarchal order. It suggests, finally, that at this moment in time and in this context, seeing a ghost was the best, perhaps the only, way this servant had to tell a suppressed story and stake a claim to a household that had excluded her.

  8. 75 FR 24549 - Merchant Marine Act and Magnuson-Stevens Fishery Conservation and Management Act (Magnuson...

    Science.gov (United States)

    2010-05-05

    ... Management Act (Magnuson-Stevens Act) Provisions; Fishing Vessel, Fishing Facility and Individual Fishing... Fisheries Finance Program (FFP or the Program) provides long-term financing to the commercial fishing and...) lending program, 16 U.S.C. 1855(i)(1). The Magnuson-Stevens Fishery Conservation and Management...

  9. Bárbara Mujica, ed., Shakespeare and the Spanish «Comedia». Translation, Interpretation, Performance. Essays in Honor of Susan L. Fischer

    Directory of Open Access Journals (Sweden)

    Alejandro García-Reidy

    2016-01-01

    Full Text Available Reseña de Bárbara Mujica, ed., Shakespeare and the Spanish «Comedia». Translation, Interpretation, Performance. Essays in Honor of Susan L. Fischer, Bucknell University Press, Lewisburg, 2013, 298 pp. ISBN 9781611485172.

  10. Autoimmune Progesterone Dermatitis Presenting as Stevens-Johnson Syndrome.

    Science.gov (United States)

    Drayer, Sara M; Laufer, Larry R; Farrell, Maureen E

    2017-10-01

    Autoimmune progesterone dermatitis is an uncommon disease presenting with cyclical skin eruptions corresponding with the menstrual cycle luteal phase. Because symptoms are precipitated by rising progesterone levels, treatment relies on hormone suppression. A 22-year-old nulligravid woman presented with symptoms mistaken for Stevens-Johnson syndrome. A cyclic recurrence of her symptoms was noted, and the diagnosis of autoimmune progesterone dermatitis was made by an intradermal progesterone challenge. After 48 months, she remained refractory to medical management and definitive surgical treatment with bilateral oophorectomy was performed. Autoimmune progesterone dermatitis is a challenging diagnosis owing to its rarity and variety of clinical presentations. Treatment centers on suppression of endogenous progesterone and avoidance of exogenous triggers. When these modalities fail, surgical management must be undertaken.

  11. Podróż, cudze cierpienie i doświadczenie historyczne: Susan Silas

    Directory of Open Access Journals (Sweden)

    Sendyka, Roma

    2014-12-01

    Full Text Available Autorka interpretuje pracę Susan Silas Helmbrechts walk (1998-2003, szczególny cykl czterdziestu pięciu zdjęć i dołączonych do nich materiałów wizualnych oraz tekstowych zbudowany podczas przejścia trasy dwustu dwudziestu pięciu mil, które w 1945 roku musiały przebyć kobiety pędzone w marszu śmierci z Helmbrecht koło Flossenbürga do czeskich Prachatic. Wykonywane zdjęcia, napotykani ludzie, w końcu – drzewa, sama materialność drogi stają się czynnikami wytwarzania własnej, indywidualnej pamięci wydarzenia sprzed lat. Silas wybiera szczególny obiekt "z marginesów Zagłady" – zapomniane zdarzenie, które przedstawia obserwując współczesne obiekty położone wzdłuż trasy tego zdarzenia. Praca Silas pozwala przyjrzeć się krytycznie koncepcji memory landscapes (gdzie w krajobrazie umiejscawia się pamięć? i zjawisku dark tourism (czy podążanie śladami więźniarek to pielgrzymka, turystyka czy terapia?. Silas problematyzuje nie tylko kwestię pamięci, bada również rodzaje nie-pamiętania. Jej kamera zostaje zwrócona ku lokalizacjom, które można nazwać "nie-miejscami pamięci".

  12. Treasure Your Exceptions: An Interview with 2017 George Beadle Award Recipient Susan A. Gerbi.

    Science.gov (United States)

    Gerbi, Susan A

    2017-12-01

    THE Genetics Society of America's (GSA) George W. Beadle Award honors individuals who have made outstanding contributions to the community of genetics researchers and who exemplify the qualities of its namesake. The 2017 recipient is Susan A. Gerbi, who has been a prominent leader and advocate for the scientific community. In the course of her research on DNA replication, Gerbi helped develop the method of Replication Initiation Point (RIP) mapping to map replication origins at the nucleotide level, improving resolution by two orders of magnitude. RIP mapping also provides the basis for the now popular use of λ-exonuclease to enrich nascent DNA to map replication origins genome-wide. Gerbi's second area of research on ribosomal RNA revealed a conserved core secondary structure, as well as conserved nucleotide elements (CNEs). Some CNEs are universally conserved, while other CNEs are conserved in all eukaryotes but not in archaea or bacteria, suggesting a eukaryotic function. Intriguingly, the majority of the eukaryotic-specific CNEs line the tunnel of the large ribosomal subunit through which the nascent polypeptide exits. Gerbi has promoted the fly Sciara coprophila as a model organism ever since she used its enormous polytene chromosomes to help develop the method of in situ hybridization during her Ph.D. research in Joe Gall's laboratory. The Gerbi laboratory maintains the Sciara International Stock Center and manages its future, actively spreading Sciara stocks to other laboratories. Gerbi has also served in many leadership roles, working on issues of science policy, women in science, scientific training, and career preparation. This is an abridged version of the interview. The full interview is available on the Genes to Genomes blog, at genestogenomes.org/gerbi. Copyright © 2017 by the Genetics Society of America.

  13. Mycoplasma pneumoniae and atypical Stevens-Johnson syndrome: a case series.

    Science.gov (United States)

    Ravin, Karen A; Rappaport, Lara D; Zuckerbraun, Noel S; Wadowsky, Robert M; Wald, Ellen R; Michaels, Marian M

    2007-04-01

    Mycoplasma pneumoniae is a common cause of community-acquired respiratory illness in the adolescent population. Stevens-Johnson syndrome is an extrapulmonary manifestation that has been associated with M. pneumoniae infections. Three adolescent males presented within a 1-month period with M. pneumoniae respiratory illnesses and severe mucositis but without the classic rash typical of Stevens-Johnson. Diagnosis was facilitated by the use of a polymerase chain reaction-based assay. This case series highlights the potential for M. pneumoniae-associated Stevens-Johnson syndrome to occur without rash and supports the use of polymerase chain reaction for early diagnosis.

  14. Genetics Home Reference: Stevens-Johnson syndrome/toxic epidermal necrolysis

    Science.gov (United States)

    ... Hung SI. Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis. ... 2012 May 29. Citation on PubMed or Free article on PubMed Central More from Genetics Home Reference ...

  15. T. Rapatsikou on  Bart and Ragg’s Wallace Stevens

    Directory of Open Access Journals (Sweden)

    2009-07-01

    Full Text Available Eeckhout, Bart and Edward Ragg, eds. Wallace Stevens Across the Atlantic (Basingstoke and New York: Palgrave Macmillan, 2008. Pp. xvii + 246. ISBN 978-0-230-53584-8.Bart Eeckhout and Edward Ragg’s edited collection of essays entitled Wallace Stevens Across the Atlantic is a diverse, well-informed and excellently conceptualized volume offering fresh insights into Wallace Stevens’ poetry. This book can serve as a good introduction to Wallace Stevens’ oeuvre for the general reader, university s...

  16. Bronchiolitis obliterans in children with Stevens-Johnson syndrome: follow-up with high resolution CT

    International Nuclear Information System (INIS)

    Kim, M.J.; Lee, K.Y.

    1996-01-01

    About one third of children with Stevens-Johnson syndrome have pulmonary involvement. As a consequence of airway epithelial injury, bronchiolitis obliterans can occur in these patients. Two cases of Stevens-Johnson syndrome-associated bronchiolitis obliterans in children were diagnosed and followed by high resolution CT without open lung biopsy. Serial changes of high resolution CT features of bronchiolitis obliterans are discussed and the literature is reviewed. (orig.)

  17. Steven johnsons syndrome and toxic epidermal necrolysis: A review

    Directory of Open Access Journals (Sweden)

    Sri ram Anne

    2014-12-01

    Full Text Available Toxic epidermal necrolysis (TEN and Stevens Johnson Syndrome (SJS are severe adverse cutaneous drug reactions that predominantly involve the skin and mucous membranes. They are characterized by mucocutaneous tenderness and typically hemorrhagic erosions, erythema and more or less severe epidermal detachment presenting as blisters and areas of denuded skin. Drugs are assumed or identified as the main cause of SJS/TEN in most cases, but Mycoplasma pneumoniae and Herpes simplex virus infections are well documented causes alongside rare cases in which the etiology remains unknown. Several drugs are at "high" risk of inducing TEN/SJS including: Allopurinol, Trimethoprim-sulfamethoxazole and other sulfonamide-antibiotics, aminopenicillins, cephalosporins, quinolones, carbamazepine, phenytoin, phenobarbital and NSAID's of the oxicam-type. Differential diagnosis includes linear IgA dermatosis and paraneoplastic pemphigus, pemphigus vulgaris and bullous pemphigoid, acute generalized exanthematous pustulosis (AGEP, disseminated fixed bullous drug eruption and staphyloccocal scalded skin syndrome (SSSS. Due to the high risk of mortality, management of patients with SJS/TEN requires rapid diagnosis, identification and interruption of the culprit drug, specialized supportive care ideally in an intensive care unit, and consideration of immunomodulating agents such as high-dose intravenous immunoglobulin therapy.

  18. Erythema multiforme and Stevens-Johnson syndrome following radiotherapy

    International Nuclear Information System (INIS)

    Yoshitake, Tadamasa; Nakamura, Katsumasa; Shioyama, Yoshiyuki

    2007-01-01

    Erythema multiforme (EM) and Stevens-Johnson syndrome (SJS) are thought to be hypersensitivity syndromes with various causes, and radiotherapy might be one of the causes of these syndromes. We herein report two cases of EM/SJS following radiotherapy. The first case was a 63-year-old woman with breast cancer. At the end of postoperative radiotherapy with 60 Gy, severe pruritic erythema appeared in the irradiated area and spread over the whole body. She was diagnosed with EM by a skin biopsy. The second case was a 77-year-old woman with uterine cervical cancer who underwent postoperative radiotherapy. At a dose of 30.6 Gy, pruritic redness appeared in the irradiated area and the precordial region, and it became widespread rapidly with polymorphic transformation. Although without any histological confirmation, SJS was strongly suspected because of her pruritic conjunctivitis. Because both patients were given medicines during irradiation, radiotherapy may not be the only cause of EM/SJS. However, it should be noted that radiotherapy might trigger EM/SJS. (author)

  19. Susan Loucks-Horsley learning model in light pollution theme: based on a new taxonomy for science education

    International Nuclear Information System (INIS)

    Liliawati, W; Utama, J A; Fauziah, H

    2016-01-01

    The curriculum in Indonesia recommended that science teachers in the elementary and intermediate schools should have interdisciplinary ability in science. However, integrated learning still has not been implemented optimally. This research is designing and applying integrated learning with Susan Loucks-Horsley model in light pollution theme. It can be showed how the student's achievements based on new taxonomy of science education with five domains: knowing and understanding, science process skill, creativity, attitudinal and connecting and applying. This research use mixed methods with concurrent embedded design. The subject is grade 8 of junior high school students in Bandung as many as 27 students. The Instrument have been employed has 28 questions test mastery of concepts, observations sheet and moral dilemma test. The result shows that integrated learning with model Susan Loucks-Horsley is able to increase student's achievement and positive characters on light pollution theme. As the results are the average normalized gain of knowing and understanding domain reach in lower category, the average percentage of science process skill domain reach in good category, the average percentage of creativity and connecting domain reach respectively in good category and attitudinal domain the average percentage is over 75% in moral knowing and moral feeling. (paper)

  20. Susan Loucks-Horsley learning model in light pollution theme: based on a new taxonomy for science education

    Science.gov (United States)

    Liliawati, W.; Utama, J. A.; Fauziah, H.

    2016-08-01

    The curriculum in Indonesia recommended that science teachers in the elementary and intermediate schools should have interdisciplinary ability in science. However, integrated learning still has not been implemented optimally. This research is designing and applying integrated learning with Susan Loucks-Horsley model in light pollution theme. It can be showed how the student's achievements based on new taxonomy of science education with five domains: knowing & understanding, science process skill, creativity, attitudinal and connecting & applying. This research use mixed methods with concurrent embedded design. The subject is grade 8 of junior high school students in Bandung as many as 27 students. The Instrument have been employed has 28 questions test mastery of concepts, observations sheet and moral dilemma test. The result shows that integrated learning with model Susan Loucks-Horsley is able to increase student's achievement and positive characters on light pollution theme. As the results are the average normalized gain of knowing and understanding domain reach in lower category, the average percentage of science process skill domain reach in good category, the average percentage of creativity and connecting domain reach respectively in good category and attitudinal domain the average percentage is over 75% in moral knowing and moral feeling.

  1. Two new tropolonic alkaloids from Colchicum speciosum Steven bulbs

    Directory of Open Access Journals (Sweden)

    S. Tayyeb*

    2017-11-01

    Full Text Available Background and objectives: The genus Colchicum belongs to the family Colchicaceae, which comprises of 19 genera, and 225 species worldwide. They have been recognized for more than 2000 years for their noticeable biological properties. The Colchicum species are well known for presence of tropolonic alkaloids, mainly colchicine. Colchicine, is still the drug of choice for treatment of gout, and is used for the treatment of a number of proinflammatory disorders, such as familial Mediterranean fever, and Behcet’s disease. Clinical studies have proved colchicine to posses potent anti-tumor activity. Colchicum speciosum Steven is an indigenous perennial herbaceous plant widely distributed in northern, central and western regions of Iran.  Methods: In the present study, the phytochemical composition of MeOH extract from bulbs of C. speciosum collected fromSavadkouh region, Iranwas investigated by combination of HPLC-PDA-MS spectrometry and NMR specroscopy. The fractionation of MeOH extract was carried out by partitioning on CH2Cl2, EtOAc and water. Results: The isolation and purification of CH2Cl2 portion by combination of reverse and normal phase chromatography resulted in the isolation, purification and identification of two new tropolonic alkaloids, compounds (1 and (2, as well as two known compound colchicine (3 and demecolcine (4. Their structures were established by extensive spectroscopic methods, including 1D (1H NMR and 2D-NMR (COSY, HSQC and HMBC. The absolute configurations of isolated compounds were established by aid of circular dichroism. Conclusion: Phytochemical investigation of CH2Cl2 extract of C. speciosum by combination of HPLC, column chromatography and hyphenated spectroscopic techniques led to identification two new alkaloids with potential as lead compounds.

  2. Susan Magoffin’s Santa Fe Days in 1846: The Value of Testimony Les journées de Santa Fé en 1846 de Susan Magoffin : la valeur du témoignage

    Directory of Open Access Journals (Sweden)

    Susanne Berthier-Foglar

    2009-11-01

    Full Text Available Susan Magoffin, la jeune épouse d’un commerçant de la piste de Santa Fe, accompagna son mari en 1846 pour un voyage où la caravane suivait de près l’Armée de l’Ouest et pendant lequel elle tint un journal. Cet article traite des 37 jours que dura la pause de la caravane à Santa Fe et aborde plus spécifiquement la façon dont l’auteur appréhendait l’altérité dans un environnement inhabituel et parfois dangereux. Pour apprécier la valeur du témoignage, je combine une analyse du discours avec une évaluation statistique du contenu. La description, parfois naïve, de Santa Fe sous l’occupation américaine illustre les raisons de la guerre contre le Mexique. En tant qu’agent de la destinée manifeste, Susan Magoffin admirait le général Kearny en lui attribuant des qualités surhumaines et en participant à ses efforts de propagande. Alors qu’elle était enracinée dans sa classe et sa culture, elle voyait la population mexicaine et les Amérindiens avec un esprit ouvert bien que ses motifs pour apprendre l’espagnol, ainsi que le métier de commerçante, avaient une fonction plus prosaïque.

  3. Toxic epidermal necrolysis and Stevens-Johnson syndrome

    Directory of Open Access Journals (Sweden)

    French Lars E

    2010-12-01

    Full Text Available Abstract Toxic epidermal necrolysis (TEN and Stevens Johnson Syndrome (SJS are severe adverse cutaneous drug reactions that predominantly involve the skin and mucous membranes. Both are rare, with TEN and SJS affecting approximately 1or 2/1,000,000 annually, and are considered medical emergencies as they are potentially fatal. They are characterized by mucocutaneous tenderness and typically hemorrhagic erosions, erythema and more or less severe epidermal detachment presenting as blisters and areas of denuded skin. Currently, TEN and SJS are considered to be two ends of a spectrum of severe epidermolytic adverse cutaneous drug reactions, differing only by their extent of skin detachment. Drugs are assumed or identified as the main cause of SJS/TEN in most cases, but Mycoplasma pneumoniae and Herpes simplex virus infections are well documented causes alongside rare cases in which the aetiology remains unknown. Several drugs are at "high" risk of inducing TEN/SJS including: Allopurinol, Trimethoprim-sulfamethoxazole and other sulfonamide-antibiotics, aminopenicillins, cephalosporins, quinolones, carbamazepine, phenytoin, phenobarbital and NSAID's of the oxicam-type. Genetic susceptibility to SJS and TEN is likely as exemplified by the strong association observed in Han Chinese between a genetic marker, the human leukocyte antigen HLA-B*1502, and SJS induced by carbamazepine. Diagnosis relies mainly on clinical signs together with the histological analysis of a skin biopsy showing typical full-thickness epidermal necrolysis due to extensive keratinocyte apoptosis. Differential diagnosis includes linear IgA dermatosis and paraneoplastic pemphigus, pemphigus vulgaris and bullous pemphigoid, acute generalized exanthematous pustulosis (AGEP, disseminated fixed bullous drug eruption and staphyloccocal scalded skin syndrome (SSSS. Due to the high risk of mortality, management of patients with SJS/TEN requires rapid diagnosis, evaluation of the prognosis

  4. [Fatal toxic respiratory epitheliolysis. Subacute tracheo-bronchial desquamation in Stevens-Johnson syndrome].

    Science.gov (United States)

    Martin, L; Hazouard, E; Michalak-Provost, S; Maurage, C; Machet, L

    2001-09-01

    Acute bronchial mucosal sloughing related to Toxic Epidermal Necrolysis (Lyell syndrome) is widely reported in literature. On the contrary severe respiratory involvement is rare in post-infectious or toxic Epitheliolysis (Stevens-Johnson syndrome). There is no well-known predictive sign of bronchial epithelium involvement. An 18-year-old patient was admitted for Stevens-Johnson syndrome related to sulfasalazine (salazosulfapyridine). There were no respiratory signs. An acute respiratory failure occurred 36 hours after from admission due to an obstructive and desquamative necrosis of the tracheobronchial epithelium. We purpose that a fiberoptic laryngoscopy should be performed even in non-dyspneic patients suffering from Stevens-Johnson syndrome if hypersecretion is present. Fiberoptic bronchoscopy can be helpful in these cases.

  5. 77 FR 27436 - Stevens Institute of Technology, et al.; Notice of Consolidated Decision on Applications for Duty...

    Science.gov (United States)

    2012-05-10

    ... Number: 12-014. Applicant: California Institute of Technology, Pasadena, CA 91125. Instrument: Nova Nano... DEPARTMENT OF COMMERCE International Trade Administration Stevens Institute of Technology, et al... Constitution Avenue NW, Washington, DC Docket Number: 12-008. Applicant: Stevens Institute of Technology...

  6. 77 FR 69929 - Western Carolina Railway Service Corporation, Steven C. Hawkins and Cheryl R. Hawkins-Continuance...

    Science.gov (United States)

    2012-11-21

    ... Railway Service Corporation, Steven C. Hawkins and Cheryl R. Hawkins--Continuance in Control Exemption--Aiken Railway Company, LLC Western Carolina Railway Service Corporation (WCRS) and Steven C. Hawkins and Cheryl R. Hawkins (the Hawkins) (collectively, Applicants) have filed a verified notice of exemption...

  7. Synthesis of (±)-amathaspiramide F and discovery of an unusual stereocontrolling element for the [2,3]-Stevens rearrangement.

    Science.gov (United States)

    Soheili, Arash; Tambar, Uttam K

    2013-10-04

    A formal total synthesis of (±)-amathaspiramide F through a tandem palladium-catalyzed allylic amination/[2,3]-Stevens rearrangement is reported. The unexpected diastereoselectivity of the [2,3]-Stevens rearrangement was controlled by the substitution patterns of an aromatic ring. This discovery represents a new stereocontrolling element for [2,3]-sigmatropic rearrangements in complex molecular settings.

  8. 78 FR 21114 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-04-09

    ... for Sustainable Fisheries, Northeast Region, NMFS (Assistant Regional Administrator), has made a... University Cooperative Extension of Suffolk County, NY. Regulations under the Magnuson-Stevens Fishery... limits to conduct onboard sampling. This project proposes to evaluate bottom trawl modifications as a...

  9. Stevens-Johnson syndrome in a patient with rheumatoid arthritis during long-term etanercept therapy.

    Science.gov (United States)

    Owczarczyk-Saczonek, Agnieszka; Zdanowska, Natalia; Znajewska-Pander, Aleksandra; Placek, Waldemar

    2016-03-31

    Etanercept and other anti-TNF-alpha agents have been indicated as a therapeutic option in severe drug reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis. Etanercept has been shown to quickly reduce the detachment of the epidermis and shorten healing time. Cases of etanercept-induced severe adverse drug reactions were also described. A 27-year-old woman with a 4-year history of etanercept and sulfasalazine treatment for rheumatoid arthritis was admitted with Stevens-Johnson syndrome. The patient received one dose of an OTC drug containing acetaminophen, phenylephrine and pheniramine two days prior to developing fist mucocutaneous symptoms. The most probable causative agent was paracetamol. Throughout the successful routine therapy of Stevens-Johnson syndrome etanercept therapy was continued. Sulfosalazin administration was stopped and administered again after recovery with no recurrence of the skin and mucosal symptoms. This case indicates that there is no justification for discontinuation of long-term anti-TNF-alpha treatment in patients who develop Stevens- Johnson syndrome / toxic epidermal necrolysis.

  10. 76 FR 11857 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-03-03

    .... The pollock peer-reviewed benchmark stock assessment review (Stock Assessment Workshop, or SAW, 50... overfishing, rebuild overfished stocks, achieve optimum yield (OY), and minimize the economic impact of... Management Act (Magnuson-Stevens Act). This action would revise the biological reference points and stock...

  11. 76 FR 56985 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-09-15

    ... to estimate total haddock catch by the herring midwater trawl fleet in these herring management areas.... 110627355-1539-02] RIN 0648-BB08 Magnuson-Stevens Fishery Conservation and Management Act Provisions... the NE Multispecies Fishery Management Plan (FMP), which increases the haddock incidental catch cap...

  12. 76 FR 43745 - Magnuson-Stevens Fishery Conservation and Management Act (MSA) Provisions; Fisheries of the...

    Science.gov (United States)

    2011-07-21

    ... during the course of the FY. Management uncertainty for the LAGC IFQ fleet is considered very low because... incorporate ACT into the LAGC IFQ fleet allocation, but chose not to apply any management uncertainty buffer... Atmospheric Administration 50 CFR Part 648 Magnuson-Stevens Fishery Conservation and Management Act (MSA...

  13. What Recourse for the Principal Abused by Community Activists? The Case of "Stevens v. Tillman."

    Science.gov (United States)

    Menacker, Julius

    1990-01-01

    "Stevens v. Tillman" illustrates the limited reach of federal law in controversies where community activists use extreme, even illegal, methods to exert their will over objecting school officials. Defamation charges against activists for verbal abuses will apparently be very difficult to sustain, given court views that being called a…

  14. Eliminating cancer stem cells: an interview with CCR’s Steven Hou | Center for Cancer Research

    Science.gov (United States)

    Steven Hou, Ph.D., senior investigator in the Basic Research Laboratory at the Center for Cancer Research describes his latest research that has uncovered potential ways to eliminate cancer stem cells and may offer hope to patients with reoccurring tumors.  Learn more...

  15. Alfred Russel Wallace’s record of his consignments to Samuel Stevens, 1854-1861

    NARCIS (Netherlands)

    Baker, D.B.

    2001-01-01

    An annotated facsimile of those pages of Alfred Russel Wallace’s notebook recording his consignments from the Malay Archipelago to his London agent, Samuel Stevens, is provided. Records of individual consignments are linked with the stages of Wallace’s and Charles Allen’s itineraries to which they

  16. 78 FR 63892 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-10-25

    .../13monkeia.html . Copies of the small entity compliance guide are available at the following internet address... Procedure Act (APA). Pursuant to section 305(c)(3)(B) of the Magnuson-Stevens Act, management measures... APA. Comments and Responses Fifteen comments were received during the public comment period on the...

  17. Steven Spielberg peab oma uut filmi koostööks Stanley Kubrickuga

    Index Scriptorium Estoniae

    2001-01-01

    30. juunil üheaegselt Jaapanis ja USAs esilinastub Steven Spielbergi "Tehisintellekt" ("A.I. Artificial Intelligence"), mille kohta režissöör Tokyos pressikonverentsil väitis, et see on õieti Stanley Kubricku film, kuna põhineb temast järelejäänud 90-leheküljelisel ideeprojektil

  18. 78 FR 38693 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-06-27

    ... Massachusetts, Dartmouth, School for Marine Science and Technology. Regulations under the Magnuson-Stevens..., 978-281-9177. SUPPLEMENTARY INFORMATION: The University of Massachusetts, Dartmouth, School for Marine... preliminary determination that an exempted fishing permit application contains all of the required information...

  19. 78 FR 21913 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-04-12

    ... Massachusetts, Dartmouth, School for Marine Science and Technology. Regulations under the Magnuson-Stevens... preliminary determination that an exempted fishing permit application contains all of the required information....'' Fax: (978) 281-9135. FOR FURTHER INFORMATION CONTACT: Jason Berthiaume, Fishery Management Specialist...

  20. Stevens-Johnson syndrome progressing to toxic epidermal necrolysis with haloperidol and carbamazepine combination

    Directory of Open Access Journals (Sweden)

    Ajay Kumar

    2011-01-01

    Full Text Available Carbamazepine and other anticonvulsants are commoner cause of severe adverse cutaneous drug reactions such as erythema multiforme, toxic epidermal necrolysis (TEN, and Stevens-Johnson syndrome (SJS. We report a case of SJS rapidly progressing to TEN with a combination of haloperidol and carbamazepine in a patient with bipolar affective disorder. The pathophysiological mechanism underlying this reaction is discussed.

  1. 78 FR 32375 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-05-30

    ..., Dartmouth, School for Marine Science and Technology. Regulations under the Magnuson-Stevens Fishery.... SUPPLEMENTARY INFORMATION: The University of Massachusetts, Dartmouth, School for Marine Science and Technology... study and examining the influence of temperature. To facilitate compensation fishing in support of this...

  2. Steven Spielberg's "Amistad": Film as History and the Trivializing of History Teaching.

    Science.gov (United States)

    Butchart, Ronald E.

    1999-01-01

    Asserts that Steven Spielberg's film "Amistad" fictionalizes the overall facts of the case by inaccurately portraying many of the events that occurred. Explains that the myth-making tradition of Hollywood changes the messages derived from the Amistad court case. Critiques the teaching kit that corresponds to the movie. (CMK)

  3. 78 FR 25685 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010

    Science.gov (United States)

    2013-05-02

    .... 111014628-3329-01] RIN 0648-BB54 Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation... implement the provisions of the Shark Conservation Act of 2010 (SCA) and prohibit any person from removing any of the fins of a shark at sea, possessing shark fins on board a fishing vessel unless they are...

  4. 77 FR 16942 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-03-23

    ... Multispecies Fishery Management Plan which was approved on March 8, 2012. This action amends the Northeast Multispecies Fishery Management Plan to explicitly define and facilitate the effective operation of state.... 110901552-20494-02] RIN 0648-BB34 Magnuson-Stevens Fishery Conservation and Management Act Provisions...

  5. Steven Spielberg: My Primary Purpose in Making "Schindler's List" Was for Education.

    Science.gov (United States)

    Feinberg, Stephen; Totten, Samuel

    1995-01-01

    Presents an interview with Steven Spielberg on his goals and methods for making "Schindler's List." Maintains that the important lessons of truth and tolerance will help prevent the Holocaust from happening again. Describes cooperative ventures with educational groups to develop instructional materials associated with the film. (CFR)

  6. ‘Speaking Kleinian’: Susan Isaacs as Ursula Wise and the Inter-War Popularisation of Psychoanalysis

    Science.gov (United States)

    Shapira, Michal

    2017-01-01

    How did the complex concepts of psychoanalysis become popular in early twentieth-century Britain? This article examines the contribution of educator and psychoanalyst Susan Isaacs (1885–1948) to this process, as well as her role as a female expert in the intellectual and medical history of this period. Isaacs was one of the most influential British psychologists of the inter-war era, yet historical research on her work is still limited. The article focuses on her writing as ‘Ursula Wise’, answering the questions of parents and nursery nurses in the popular journal Nursery World, from 1929 to 1936. Researched in depth for the first time, Isaacs’ important magazine columns reveal that her writing was instrumental in disseminating the work of psychoanalyst Melanie Klein in Britain. Moreover, Isaacs’ powerful rebuttals to behaviourist, disciplinarian parenting methods helped shift the focus of caregivers to the child’s perspective, encouraging them to acknowledge children as independent subjects and future democratic citizens. Like other early psychoanalysts, Isaacs was not an elitist; she was in fact committed to disseminating her ideas as broadly as possible. Isaacs taught British parents and child caregivers to ‘speak Kleinian’, translating Klein’s intellectual ideas into ordinary language and thus enabling their swift integration into popular discourse. PMID:28901872

  7. Investigation of Monnose-Binding Lectin gene Polymorphism in Patients with Erythema Multiforme, Stevens-Johnson Syndrome and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome

    Directory of Open Access Journals (Sweden)

    Sevil Toka

    2012-09-01

    Full Text Available Objective: Monnose-Binding lectin (MBL appears to play an important role in the immune system. The genetic polymorphisms in the MBL2 gene can result in a reduction of serum levels, leading to a predisposition to recurrent infection. The aim of this study is to investigate the influence of a polymorphism in codon 54 of the MBL2 gene on the susceptibility to Erythema Multiforme, Stevens-Johnson Syndrome and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome (EM, SJS and SJS/TEN overlap syndrome. Material and Methods: Our study included 64 patients who were clinically and/or histopathologically diagnosed with EM, SJS, and SJS/TEN overlap syndrome and 66 healthy control subjects who were genotyped for the MBL2 gene codon 54 polymorphism using the PCR-RFLP method. For all statistical analyses, the level of significance was set at p<0.05. Results: The prevalence of the B allele was 18% in the EM, SJS and SJS/TEN patient groups and 13% in the control group. No significant differences in allele frequencies of any polymorphism were observed between the patient and control groups, although the B allele was more frequent in the patient groups (p=0.328.Conclusion: Our results provide no evidence of a relationship between MBL2 gene codon 54 polymorphism and the susceptibility to EM, SJS and SJS/TEN overlap syndrome. However, these findings should be confirmed in studies with a larger sample size.

  8. 2012 ARPA-E Energy Innovation Summit: Fireside Chat with Steven Chu and Bill Gates

    Energy Technology Data Exchange (ETDEWEB)

    Chu, Steven; Gates, Bill; Podesta, John

    2012-02-28

    The third annual ARPA-E Energy Innovation Summit was held in Washington D.C. in February, 2012. The event brought together key players from across the energy ecosystem - researchers, entrepreneurs, investors, corporate executives, and government officials - to share ideas for developing and deploying the next generation of energy technologies. This video captures a session called Fireside Chat that featured Steven Chu, the Secretary of Energy, and Bill Gates, Chairman of Microsoft Corporation. The session is moderated by John Podesta, Chair of the Center for American Progress. Energy Secretary Steven Chu and Microsoft Founder and Chairman Bill Gates exchanged ideas about how small businesses and innovators can overcome the challenges that face many startups.

  9. Stevens Johnson Syndrome in a patient undergoing gynaecological brachytherapy: An association or an incident?

    International Nuclear Information System (INIS)

    Ferreira, M. R.; Amado, A.; Jorge, M.; Grillo, I. M.

    2011-01-01

    Background: Stevens Johnson Syndrome and Erythema Multiforme are hypersensitivity skin reactions generally arising in the context of multiple causes. Radiation therapy is considered to be one of these causes, although most reports are hindered by concomitant medications. Aim: The aim of this paper was to present a case of Stevens Johnson Syndrome arising in a patient undergoing gynaecological brachytherapy with an unusual presentation. Case:We describe a case of a 56-year-old woman with endometrial cancer undergoing adjuvant gynaecological radiotherapy. While undergoing a gynaecological brachytherapy boost, she developed bilateral conjunctivitis that progressed to oral mucositis and pruritic erythema with sloughing of the skin on her arms and legs but not the torso or irradiated fields (namely the vaginal mucosa). Conclusion: This case illustrates the association of RT/SJS; however, it also raises the question of patients undergoing RT being more susceptible to SJS as opposed to a direct cause of the disease. (authors)

  10. Concurrence of Stevens-Johnson Syndrome and Bilateral Parotitis after Minocycline Therapy

    Directory of Open Access Journals (Sweden)

    Jimi Yoon

    2010-06-01

    Full Text Available Minocycline is an antibiotic of tetracycline derivatives that is commonly used in the treatment of moderate to severe acne vulgaris. It has been reported to cause rare adverse events from mild cutaneous eruption to severe forms including drug-induced lupus, serum sickness-like reaction, and hypersensitivity reactions, etc. The risks of adverse events attributed to minocycline have not been ascertained reliably and there are concerns about the safety of minocycline which could possibly result in life-threatening events such as the Stevens-Johnson syndrome. Here we demonstrate an unusual case of Stevens-Johnson syndrome in conjunction with bilateral parotitis after the intake of minocycline in a Korean boy suggesting discreet use of the drug.

  11. Síndrome de Stevens-Johnson: Presentación de 1 caso

    Directory of Open Access Journals (Sweden)

    Luisa María Pacheco Álvarez

    2001-12-01

    Full Text Available El síndrome de Stevens-Johnson, es una enfermedad inflamatoria aguda, originada por una hipersensibilidad, que incluye la piel y las membranas mucosas; en una forma mayor pone en peligro la vida del paciente. Puede ser inducida por muchos factores precipitantes, desde los medicamentos hasta una infección. La afección se caracteriza por una súbita erupción morfológicamente variable, acompañada de estomatitis y oftalmia. En este trabajo se presenta un niño de 8 años de edad, con la entidad clínica en forma muy severa, el síndrome de Stevens-Johnson, que involucra manifestaciones cutáneas, oculares y de la mucosa oral, acompañada de otras complicaciones graves, por lo que requirió terapéutica en cuidados intensivos, y se logró una evolución satisfactoria del paciente.Stevens-Johnson syndrome is an acute inflammatory disease caused by a hypersensibility that includes the skin and the mucous membranes and that in a severe form endangers the patient’s life. It may be induced by many precipitating factors, from drugs to infection. The affection is characterized by a sudden morphologically variable rash, accompanied with stomatitis and ophthalmia. An 8-year-old boy suffering from this clinical entity in a very severe form, Stevens-Johnson syndrome, with skin , ocular and oral mucosa manifestations and with other serious complications, is presented in this paper. He had to be treated at the ICU and a satisfactory evolution was attained.

  12. Pediatric Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Halted by Etanercept.

    Science.gov (United States)

    Gavigan, Geneviève M; Kanigsberg, Nordau D; Ramien, Michele L

    2018-02-01

    We report a case of an 11-year-old female with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) overlap, most likely triggered by sulfamethoxazole-trimethoprim, who was treated with the combination of methylprednisolone, cyclosporine, and etanercept. Her condition stabilized and her skin involvement did not progress after the addition of etanercept. To our knowledge, this is the first report of etanercept for pediatric SJS/TEN.

  13. Evaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome

    Directory of Open Access Journals (Sweden)

    Luciana Frizon

    2014-03-01

    Full Text Available OBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome. The information gathered included the patient's sex and age, the duration of disease, the cause of Stevens-Johnson syndrome, and treatments. Scrapings of the inferior conjunctival fornix were performed in both eyes. Fourteen days before scraping, the patients were asked to interrupt all topical medication and start using 0.5% nonpreserved methylcellulose. The microbiological evaluation included microorganism identification and determination of antibiotic sensitivity. RESULTS: Of 22 patients (41 eyes, 14 (64% were females, and eight (36% were males. The mean age was 33.2 years, and the mean duration of disease was 15.6 years. Visual acuity ranged from light perception to 20/25 (1.57 logMar. The treatment received by most patients consisted of tear substitutes, topical antibiotics, and contact lenses. Bacterial identification was positive in 39 eyes (95% and negative in two eyes (5%. Gram-positive cocci accounted for 55.5% of the microorganisms, whereas gram-positive bacilli and gram-negative bacilli accounted for 19% and 25.5%, respectively. Half of the patients (54% had multiple bacterial species in their flora, and only one bacterial species was identified in the other half. Resistant bacteria were isolated from four eyes. The antibiotic sensitivity results for the Streptococcus group showed the lowest sensitivity and the highest microbial resistance identified. CONCLUSION: Patients with Stevens-Johnson syndrome have a diverse conjunctival flora that includes many pathogenic species.

  14. Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome

    OpenAIRE

    Burkhart, Keith K.; Abernethy, Darrell; Jackson, David

    2015-01-01

    Drug features that are associated with Stevens-Johnson syndrome (SJS) have not been fully characterized. A molecular target analysis of the drugs associated with SJS in the FDA Adverse Event Reporting System (FAERS) may contribute to mechanistic insights into SJS pathophysiology. The publicly available version of FAERS was analyzed to identify disproportionality among the molecular targets, metabolizing enzymes, and transporters for drugs associated with SJS. The FAERS in-house version was al...

  15. Stevens-Johnson syndrome following use of metronidazole in a dental patient.

    Science.gov (United States)

    Mazumdar, Goutameswar; Shome, Koushik

    2014-01-01

    Metronidazole alone rarely causes Stevens-Johnson syndrome (SJS). We present a case of an elderly male patient who, following metronidazole use, developed neurological symptoms followed by pain and blisters on both soles, erythema of face and neck, scrotal itching and erosion, and hemorrhagic encrustation around the lips and oral mucous membrane. Initial neurological symptoms followed by mucocutaneous manifestation of SJS following metronidazole use is probably a new presentation of this case.

  16. SU-E-T-540: Volumetric Modulated Total Body Irradiation Using a Rotational Lazy Susan-Like Immobilization System

    International Nuclear Information System (INIS)

    Gu, X; Hrycushko, B; Lee, H; Lamphier, R; Jiang, S; Abdulrahman, R; Timmerman, R

    2014-01-01

    Purpose: Traditional extended SSD total body irradiation (TBI) techniques can be problematic in terms of patient comfort and/or dose uniformity. This work aims to develop a comfortable TBI technique that achieves a uniform dose distribution to the total body while reducing the dose to organs at risk for complications. Methods: To maximize patient comfort, a lazy Susan-like couch top immobilization system which rotates about a pivot point was developed. During CT simulation, a patient is immobilized by a Vac-Lok bag within the body frame. The patient is scanned head-first and then feet-first following 180° rotation of the frame. The two scans are imported into the Pinnacle treatment planning system and concatenated to give a full-body CT dataset. Treatment planning matches multiple isocenter volumetric modulated arc (VMAT) fields of the upper body and multiple isocenter parallel-opposed fields of the lower body. VMAT fields of the torso are optimized to satisfy lung dose constraints while achieving a therapeutic dose to the torso. The multiple isocenter VMAT fields are delivered with an indexed couch, followed by body frame rotation about the pivot point to treat the lower body isocenters. The treatment workflow was simulated with a Rando phantom, and the plan was mapped to a solid water slab phantom for point- and film-dose measurements at multiple locations. Results: The treatment plan of 12Gy over 8 fractions achieved 80.2% coverage of the total body volume within ±10% of the prescription dose. The mean lung dose was 8.1 Gy. All ion chamber measurements were within ±1.7% compared to the calculated point doses. All relative film dosimetry showed at least a 98.0% gamma passing rate using a 3mm/3% passing criteria. Conclusion: The proposed patient comfort-oriented TBI technique provides for a uniform dose distribution within the total body while reducing the dose to the lungs

  17. Comparison of Olive Tipped and Conventional Steven's Cannula for Sub-Tenon Ophthalmic Anesthesia.

    Science.gov (United States)

    Al-Motowa, Saeed; Ahmad, Nauman; Khandekar, Rajiv; Zahoor, Abdul

    2016-01-01

    To compare the efficacy of the olive tipped (OT) cannula to the conventional Steven's cannula for sub-Tenon block (STB) before cataract surgery. This prospective, randomized, double-masked compared STB delivered in cataract surgery patients with an OT cannula or a conventional Steven's cannula (ST). Outcome variables included the akinesia score and lid movement scores at 5 and 10 min. The patient perception of pain during delivery of the STB and surgery were also compared between groups. Surgeon satisfaction with anesthesia was compared between groups. P <0.05 was statistically significant. There were sixty patients in each group. The age between groups was not statistically different ( P = 0.4). The body mass index was higher in the ST group compared to the OT group ( P < 0.001). The akinesia score at 5 and 10 min did not differ between groups ( P = 0.07 and P = 0.6, respectively). The patient perception of pain during STB and surgery were similar between groups ( P = 0.1 and P = 0.06, respectively). There were six patients with mild chemosis and redness in the OT group and 15 patients in the ST group. An OT cannula is equally effective as the conventional Steven's cannula for delivering STB anesthesia before cataract surgery.

  18. Fundamental Flaws In The Derivation Of Stevens' Law For Taste Within Norwich's Entropy Theory of Perception

    International Nuclear Information System (INIS)

    Nizami, Lance

    2010-01-01

    Norwich's Entropy Theory of Perception (1975-present) is a general theory of perception, based on Shannon's Information Theory. Among many bold claims, the Entropy Theory presents a truly astounding result: that Stevens' Law with an Index of 1, an empirical power relation of direct proportionality between perceived taste intensity and stimulus concentration, arises from theory alone. Norwich's theorizing starts with several extraordinary hypotheses. First, 'multiple, parallel receptor-neuron units' without collaterals 'carry essentially the same message to the brain', i.e. the rate-level curves are identical. Second, sensation is proportional to firing rate. Third, firing rate is proportional to the taste receptor's 'resolvable uncertainty'. Fourth, the 'resolvable uncertainty' is obtained from Shannon's Information Theory. Finally, 'resolvable uncertainty' also depends upon the microscopic thermodynamic density fluctuation of the tasted solute. Norwich proves that density fluctuation is density variance, which is proportional to solute concentration, all based on the theory of fluctuations in fluid composition from Tolman's classic physics text, 'The Principles of Statistical Mechanics'. Altogether, according to Norwich, perceived taste intensity is theoretically proportional to solute concentration. Such a universal rule for taste, one that is independent of solute identity, personal physiological differences, and psychophysical task, is truly remarkable and is well-deserving of scrutiny. Norwich's crucial step was the derivation of density variance. That step was meticulously reconstructed here. It transpires that the appropriate fluctuation is Tolman's mean-square fractional density fluctuation, not density variance as used by Norwich. Tolman's algebra yields a 'Stevens Index' of -1 rather than 1. As 'Stevens Index' empirically always exceeds zero, the Index of -1 suggests that it is risky to infer psychophysical laws of sensory response from information theory

  19. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and Treatment With a Biologic: A Case Report.

    Science.gov (United States)

    Chong, Ian; Chao, Alice

    2017-01-01

    One of the most dangerous dermatologic emergencies is Stevens-Johnson Syndrome (SJS)/toxic epidermal necrolysis (TEN). Although a rare disease, it can often lead to significant mortality. In this case report, we present a 77-year-old man who developed a sloughing rash that was secondary to a nonsteroidal anti-inflammatory drug. In addition to the recommended supportive care, the patient was treated with etanercept, a new, less commonly used intervention. We provide a brief review of SJS/TEN. Nonsteroidal anti-inflammatory drugs are a rare cause of SJS/TEN, and additionally, the use of biologics is a novel treatment modality for SJS/TEN.

  20. Low amplitude impact of PBX 9501: Modified Steven spigot gun tests

    Energy Technology Data Exchange (ETDEWEB)

    Idar, D.J.; Lucht, R.A.; Straight, J.W. [and others

    1998-12-01

    Low-velocity mechanical impact and subsequent high explosive (HE) reaction are of concern in credible accident scenarios involving the handling, transport, and storage of nuclear weapons. Using modified Steven spigot gun tests, the authors have investigated the high-explosive violent-reaction (HEVR) potential of PBX 9501 to low-amplitude insult. Reliable modeling predictions require that one identify the relevant parameters and behavioral responses that are key to the reaction mechanism(s) in PBX 9501. Additional efforts have been targeted at identifying relevant differences in the response between baseline and stockpile-aged PBX 9501 to low-velocity impacts.

  1. Tandem catalytic allylic amination and [2,3]-Stevens rearrangement of tertiary amines.

    Science.gov (United States)

    Soheili, Arash; Tambar, Uttam K

    2011-08-24

    We have developed a catalytic allylic amination involving tertiary aminoesters and allylcarbonates, which is the first example of the use of tertiary amines as intermolecular nucleophiles in metal-catalyzed allylic substitution chemistry. This process is employed in a tandem ammonium ylide generation/[2,3]-rearrangement reaction, which formally represents a palladium-catalyzed Stevens rearrangement. Low catalyst loadings and mild reaction conditions are compatible with an unprecedented substrate scope for the ammonium ylide functionality, and products are generated in high yields and diastereoselectivities. Mechanistic studies suggested the reversible formation of an ammonium intermediate.

  2. Guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis: An Indian perspective.

    Science.gov (United States)

    Gupta, Lalit Kumar; Martin, Abhay Mani; Agarwal, Nidheesh; D'Souza, Paschal; Das, Sudip; Kumar, Rajesh; Pande, Sushil; Das, Nilay Kanti; Kumaresan, Muthuvel; Kumar, Piyush; Garg, Anubhav; Singh, Saurabh

    2016-01-01

    Stevens-Johnson syndrome and toxic epidermal necrolysis are severe, life-threatening mucocutaneous adverse drug reactions with a high morbidity and mortality that require immediate medical care. The various immunomodulatory treatments include systemic corticosteroids, cyclosporine, intravenous immunoglobulin, cyclophosphamide, plasmapheresis and tumor necrosis factor-α inhibitors. The ideal therapy of Stevens-Johnson syndrome/toxic epidermal necrolysis still remains a matter of debate as there are only a limited number of studies of good quality comparing the usefulness of different specific treatments. The aim of this article is to comprehensively review the published medical literature and frame management guidelines suitable in the Indian perspective. The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) assigned the task of preparing these guidelines to its special interest group on cutaneous adverse drug reactions. The group performed a comprehensive English language literature search for management options in Stevens-Johnson syndrome/toxic epidermal necrolysis across multiple databases (PubMed, EMBASE, MEDLINE and Cochrane) for keywords (alone and in combination) and MeSH items such as "guidelines," "Stevens-Johnson syndrome," "toxic epidermal necrolysis," "corticosteroids," "intravenous immunoglobulin," "cyclosporine" and "management." The available evidence was evaluated using the strength of recommendation taxonomy and graded using a three-point scale. A draft of clinical recommendations was developed on the best available evidence which was also scrutinized and critically evaluated by the IADVL Academy of Dermatology. Based on the inputs received, this final consensus statement was prepared. A total of 104 articles (meta-analyses, prospective and retrospective studies, reviews [including chapters in books], previous guidelines [including Indian guidelines of 2006] and case series) were critically evaluated and the evidence

  3. Mycoplasma pneumoniae-Induced-Stevens Johnson Syndrome: Rare Occurrence in an Adult Patient

    Directory of Open Access Journals (Sweden)

    Samad Rasul

    2012-01-01

    Full Text Available Stevens-Johnson syndrome (SJS is an uncommon occurrence in Mycoplasma pneumoniae (M. pneumoniae infection (1–5% and has been mainly reported in children and young adults. We present a case of SJS in a 32-year-old male induced by M. pneumoniae infection. This patient presented with fever, cough, and massive occupation of mucus membranes with swelling, erythema, and necrosis accompanied by a generalized cutaneous rash. He clinically responded after treatment with antibiotics and IVIG. SJS is usually a drug-induced condition; however, M. pneumoniae is the commonest infectious cause and should be considered in the differential diagnosis.

  4. Síndrome de Stevens-Johnson: presentación de un caso

    OpenAIRE

    Fernández Brizuela, Ener de Jesús; Morales Díaz, Felicia

    2011-01-01

    Fundamento: el síndrome de Stevens-Johnson, también llamado eritema multiforme mayor, se caracteriza por una serie de lesiones cutáneas de diversa morfología, es una grave lesión en la cual están afectadas al menos dos membranas mucosas y la piel. La patogenia de esta enfermedad es desconocida aunque generalmente se considera que es provocada por una reacción de hipersensibilidad a drogas, infecciones y exposición a sustancias tóxicas. Caso clínico: esta afección fue diagnosticada en un niño ...

  5. Some assembly required: Contributions of Tom Stevens' lab to the V-ATPase field.

    Science.gov (United States)

    Graham, Laurie A; Finnigan, Gregory C; Kane, Patricia M

    2018-06-01

    Tom Stevens' lab has explored the subunit composition and assembly of the yeast V-ATPase for more than 30 years. Early studies helped establish yeast as the predominant model system for study of V-ATPase proton pumps and led to the discovery of protein splicing of the V-ATPase catalytic subunit. The Vma - phenotype, characteristic of loss-of-V-ATPase activity in yeast was key in determining the enzyme's subunit composition via yeast genetics. V-ATPase subunit composition proved to be highly conserved among eukaryotes. Genetic screens for new vma mutants led to identification of a set of dedicated V-ATPase assembly factors and helped unravel the complex pathways for V-ATPase assembly. In later years, exploration of the evolutionary history of several V-ATPase subunits provided new information about the enzyme's structure and function. This review highlights V-ATPase work in the Stevens' lab between 1987 and 2017. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Are steroids effective in toxic epidermal necrolysis and Stevens-Johnson syndrome?

    Directory of Open Access Journals (Sweden)

    Rodrigo Meza

    2017-06-01

    Full Text Available Resumen La necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson son reacciones cutáneas adversas graves a medicamentos e infecciones. Los corticoides se describen como una alternativa terapéutica, sin embargo, su uso es aún controvertido. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en múltiples bases de datos, identificamos cuatro revisiones sistemáticas que en conjunto incluyen once estudios primarios que responden la pregunta de interés. Extrajimos los datos y preparamos una tabla de resumen de los resultados utilizando el método GRADE. Concluimos que no está claro si los corticoides disminuyen la mortalidad o la estadía hospitalaria en la necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson porque la certeza de la evidencia es muy baja.

  7. Review of The Joy of x: A Guided Tour of Math, from One to Infinity by Steven Strogatz

    OpenAIRE

    Michael T. Catalano

    2014-01-01

    Strogatz, Steven. The Joy of x: A Guided Tour of Math, from One to Infinity, (New York, NY, Houghton Mifflin Harcourt, 2012). 316 pp. ISBN 978-0-547-51765-0 The Joy of x: A Guided Tour of Math, from One to Infinity, by Steven Strogatz, is an engaging and example-filled argument for mathematics as a valuable and enjoyable activity. The thirty chapters are divided into six parts, entitled Numbers, Relationships, Shapes, Change, Data, and Frontiers. The discussion ranges from intuitive expl...

  8. 78 FR 36149 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010; Correction

    Science.gov (United States)

    2013-06-17

    .... 111014628-3329-01] RIN 0648-BB54 Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation.... SUMMARY: NMFS published a proposed rule on May 2, 2013, to implement provisions of the Shark Conservation Act of 2010 (SCA) that prohibit any person from removing any of the fins of a shark at sea, possessing...

  9. 78 FR 40687 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010; Extension...

    Science.gov (United States)

    2013-07-08

    .... 111014628-3329-01] RIN 0648-BB54 Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation... period. SUMMARY: NMFS published a proposed rule on May 2, 2013, to implement provisions of the Shark Conservation Act of 2010 (SCA) that prohibit any person from removing any of the fins of a shark at sea...

  10. Erythema multiforme and Stevens-Johnson syndrome in patients receiving cranial irradiation and phenytoin

    International Nuclear Information System (INIS)

    Delattre, J.Y.; Safai, B.; Posner, J.B.

    1988-01-01

    In 15 months we encountered eight patients with intracranial tumors who developed erythema multiforme (EM) or erythema multiforme bullosa (Stevens-Johnson syndrome). All occurred shortly after use of phenytoin (DPH) and brain radiation therapy (WBRT). The clinical picture differed from the classic form of EM in that the erythema began on the scalp and spread to the extremities, progressing in three cases to extensive bullous formation. There were no cases of EM among patients who received either DPH or radiotherapy alone. The combination of DPH, WBRT, and tapering of steroids seems to predispose to EM. The pathogenesis of the disorder is probably immunologic. In the absence of seizures, anticonvulsants should not be given routinely to patients with brain tumors. When anticonvulsants are necessary in patients scheduled for WBRT, DPH may not be the drug of choice

  11. Stevens-Johnson syndrome in patients on phenytoin and cranial radiotherapy

    International Nuclear Information System (INIS)

    Khafaga, Y.M.; Jamshed, A.; Allam, A.A.K.; Ezzat, A.; Gray, A.J.; Schultz, H.; Mourad, W.A.; Al Eisa, A.

    1999-01-01

    The use of phenytoin as a prophylactic anticonvulsant after brain surgery, particularly for brain tumors, is a common practice, regardless of whether the patient has a previous history of convulsions. This treatment policy assumes that the benefits exceed the risks. Four cases are described of adverse reactions of phenytoin during the cocomitant use of cranial radiotherapy. In one patient this proved fatal. There is increasing anecdotal support in the literature for a synergistic effect between phenytoin therapy and cranial radiotherapy that can result in the life-threatening Stevens-Johnson syndrome. While the association is uncommon, four cases within 24 months in one department suggest that the routine use of postoperative phenytoin as a prophylactic anticonvulsant in the absence of a history of seizures may not be warranted, particularly if the patient is to receive cranial radiotherapy. (orig.)

  12. Irradiated fields spared Stevens-Johnson syndrome in a patient undergoing radiotherapy for bone metastases

    International Nuclear Information System (INIS)

    Musio, D.; Parisi, E.; Dionisi, F.

    2009-01-01

    Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe, rare, and life-threatening adverse reactions to medications. Their incidence is approximately two patients per million population per year. Several cases have been reported in the literature in which SJS and TEN have occurred in patients with a neoplasm undergoing radiation therapy and who are taking an anticonvulsant. We report a case of SJS-TEN that developed in a 51-year-old woman with nonresectable non-small-cell lung cancer during treatment with phenobarbital plus radiation therapy for bone metastases but in whom the irradiated areas did not exhibit the SJS skin reaction. To our knowledge, no similar cases have been reported in the literature. (author)

  13. Representations of nurses and individuals in psychological distress in the photographic exhibit USAnatomy, by Steven Klein.

    Science.gov (United States)

    Carvalho, Evanilda Souza de Santana; Araújo, Edna Maria de; Santos, Silvone Santa Bárbara da Silva; Santos, Alexandro Gesner Gomes Dos

    2016-06-01

    Objectives To analyze the representations of the nurse and individual in mental suffering portrayed in the photographic work by Steven Klein, in the USAnatomy exhibit held at the Museum of Sculpture (Museu da escultura) in São Paulo, in 2011. Methods Qualitative study carried out in 2012. Three photographs were submitted to iconographic analysis. The interpretation of the findings was based on theoretical frameworks of Foucault and Bourdieu on power relations. Results The nurse is represented as a sensual, insensitive person, with the power to control and torture while the person in psychological distress is represented as dirty, imprisoned and subjected to an asymmetrical relationship of power with the nurse. Final considerations Relationships of submission and symbolic dominance, in which the person in psychological distress has their body molded by discipline imposed by the nurse. Stereotypes of the image of the nurse oppose the ideology of the profession, which is to ensure the integrity of those being cared for.

  14. Comprehensive approach to ocular consequences of Stevens Johnson Syndrome - the aftermath of a systemic condition.

    Science.gov (United States)

    Iyer, Geetha; Srinivasan, Bhaskar; Agarwal, Shweta; Kamala Muralidharan, Seema; Arumugam, Sumathi

    2014-03-01

    Stevens Johnson Syndrome (SJS) can lead to end stage corneal blindness. This study describes the comprehensive treatment measures and their outcomes in the management of ocular sequelae and complications of SJS. Four hundred sixty-four eyes of 232 patients of SJS who underwent surgical intervention (punctal cautery, mucus membrane grafting for lid margin keratinisation, fornix reconstructive procedures, tectonic procedures, keratoplasty and keratoprosthesis) were studied. It was a non-comparative, retrospective, interventional case series. The primary outcome was the change in the best corrected visual acuity (BCVA). Secondary outcome measures included an improvement in the ocular surface status as indicated by corneal epithelial fluorescein staining and Schirmer's I strip wetting. The BCVA and the ocular surface status improved and/or stabilized in > 70 % of eyes following punctal cautery (n = 160) and > 80 % of eyes following lid margin mucus membrane grafting (n = 238). BCVA improved in 50 % of eyes following fornix reconstructive procedures (n = 24) with COMET (n = 6), in 63.9 % eyes with the Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) lens (n = 36), in 81.8 % of eyes after cataract surgery (n = 22). A BCVA of ≥20/200 was achieved in 72.34 % of eyes following keratoprostheses procedures (n = 47). The mean duration of follow up was 53.3 ± 15.2 months. The ocular sequelae of Stevens Johnson Syndrome can be blinding. They need to be identified and addressed early to retard the continued deterioration of the ocular surface. Our study aims to highlight the problem as well as the importance of comprehensive measures in the management of this potentially blinding disorder.

  15. Endoscopic cyclophotocoagulation in refractory glaucoma after osteo-odonto-keratoprosthesis in Stevens-Johnson syndrome: a case report.

    Science.gov (United States)

    Forlini, Matteo; Adabache-Guel, Tania; Bratu, Adriana; Rossini, Paolo; Mingaine, Mpekethu Sam; Cavallini, Gian Maria; Forlini, Cesare

    2014-01-01

    To report successful treatment of refractive glaucoma in a patient submitted to osteo-odonto-keratoprosthesis surgery for Stevens-Johnson syndrome. An interventional case report. The patient is a 62-year-old Indian man with known Stevens-Johnson syndrome since 1972 secondary to tetracycline therapy, with bilateral dry eye and corneal blindness. He underwent symblepharon release surgery with mucous membrane graft in both eyes. Osteo-odonto-keratoprosthesis surgery was later performed on the left eye. He was submitted to 2 Ahmed valve implants to control secondary glaucoma but visual fields continued to worsen; hence, he underwent endoscopic 140° cyclophotocoagulation with a good control of IOP. Endoscopic cyclophotocoagulation as alternative treatment provides good results in refractory glaucoma after osteo-odonto-keratoprosthesis surgery.

  16. Stevens-Johnson syndrome and toxic epidermal necrolysis: an update on pharmacogenetics studies in drug-induced severe skin reaction.

    Science.gov (United States)

    Rufini, Sara; Ciccacci, Cinzia; Politi, Cristina; Giardina, Emiliano; Novelli, Giuseppe; Borgiani, Paola

    2015-11-01

    Stevens-Johnson syndrome and toxic epidermal necrolysis are severe, life-threatening drug reactions involving skin and membranes mucous, which are associated with significant morbidity and mortality and triggered, especially by drug exposure. Different studies have demonstrated that drug response is a multifactorial character and that the interindividual variability in this response depends on both environmental and genetic factors. The last ones have a relevant significance. In fact, the identification of new specific genetic markers involved in the response to drugs, will be of great utility to establish a more personalized therapeutic approach and to prevent the appearance of these adverse reactions. In this review, we summarize recent progresses in the Pharmacogenetics studies related to Stevens-Johnson syndrome/toxic epidermal necrolysis reporting the major genetic factors identified in the last years as associated with the disease and highlighting the use of some of these genomic variants in the clinical practice.

  17. Stevens - Johnson Syndrome Induced by Combination of Lamotrigine and Valproic Acid in a 9-Year-Old Boy

    LENUS (Irish Health Repository)

    Maduemem, K

    2017-06-01

    We describe the case history of a 9-year-old boy who developed Stevens-Johnson syndrome (SJS) following concomitant use of valproic acid and lamotrigine. He presented with rash and fever several weeks after introduction of lamotrigine, having been on valproic acid for seizure disorder. SJS happens to be one of the rare adverse reactions of antiepilepsy drugs (AED). Management is mainly supportive with care escalation when necessary because of the significant morbidity.

  18. Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus - A Case Report -

    OpenAIRE

    Bae, Hyun Min; Park, Yoo Jung; Kim, Young Hoon; Moon, Dong Eon

    2013-01-01

    Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommen...

  19. Osteo-odonto keratoprosthesis in Stevens-Johnson syndrome: a case report.

    Science.gov (United States)

    Sc, Reddy; I, Tajunisah; T, Tan D

    2011-01-01

    To report a successful osteo-odonto keratoprosthesis (OOKP) procedure in a case of end stage of corneal blindness due to Stevens-Johnson syndrome (SJS). An interventional case report. We describe a 35-year-old Indian woman, a known case of SJS with bilateral dry eyes and corneal blindness (failed corneal graft with vascularised total corneal opacity in the right eye and non-healing corneal ulcer in the left eye). Vision was hand movement only in both eyes. The corneal ulcer healed with medical treatment resulting in vascularised total corneal opacity with no improvement in vision. OOKP was performed in the right eye and the vision was improved from hand movement to 6/6. The same vision was maintained in the right eye at the last follow-up 5 years after surgery. OOKP provides good visual rehabilitation with long-term anatomically stable prosthesis in patients with end-stage of ocular surface disorders and corneal blindness secondary to SJS.

  20. A Tribute to Professor Steven L. Wechsler (1948-2016): The Man and the Scientist.

    Science.gov (United States)

    Nesburn, Anthony B; BenMohamed, Lbachir

    2017-01-01

    Professor Steven L. Wechsler, a world-renowned eye researcher and virologist, passed away unexpectedly on June 12, 2016 at the age of 68. Many scientists came to know Professor Wechsler as a gifted researcher in the field of ocular Herpes Simplex Virus (HSV-1) latency, reactivation, and pathogenesis. Professor Wechsler published over 150 peer-reviewed scientific papers during his career, pushing forward the frontiers of his field eye research. His colleagues would say, 'Steve literally wrote the book on herpes latency and reactivation.' He was the first to show that the HSV-1 latency-associated transcript (LAT) is essential for the HSV-1 high spontaneous reactivation phenotype and that LAT has anti-apoptosis activity. This discovery of LAT's anti-apoptosis activity, which is a key factor in how the LAT gene enhances reactivation, was published in Science in 2000 and created a new paradigm that greatly increased understanding of HSV-1 latency and reactivation. In collaboration with Professor Lbachir BenMohamed, an immunologist, they later demonstrated that LAT also acts as an immune evasion gene. He was a caring scientist who truly enjoyed working and sharing his experience and expertise with young researchers. He will be remembered as a significant pillar within scientific and ocular herpes research communities worldwide. Professor Wechsler's dedication to science, his compassionate character, and wonderful sense of humor were exemplary. We, who were his friends and colleagues, will mourn his passing deeply.

  1. Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report

    Directory of Open Access Journals (Sweden)

    Jayanta Kumar Das

    2011-01-01

    Full Text Available An 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular examinations were not possible due to the symblepharon. B-scan ultrasonography revealed acoustically clear vitreous, normal chorioretinal thickness, and normal optic nerve head, with an attached retina. Conjunctivo-corneal adhesion released by superficial lamellar dissection of the cornea. Ocular surface reconstruction was carried out with a buccal mucous membrane. A bandage contact lens was placed over the cornea followed by the symblepharon ring to prevent further adhesion. The mucosal graft was well taken up along with corneal re-epithelization. Best corrected visual acuity of 20/120 in both sides after 1 month and 20/80 after 3 months was achieved and maintained till the 2.5-year follow-up.

  2. The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China

    Directory of Open Access Journals (Sweden)

    Shang-Chen Yang

    2018-01-01

    Full Text Available Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN are life-threatening disease. However, there are only few epidemiologic studies of SJS/TEN from China. To analyze the clinical characteristics, causality, and outcome of treatment for SJS/TEN in China, we reviewed case reports of patients with SJS/TEN from the China National Knowledge Infrastructure (CNKI and Wanfang database from 2006 to 2016 and patients with SJS/TEN who were admitted to the First Affiliated Hospital of Fujian Medical University during the same period. There were 166 patients enrolled, including 70 SJS, 2 SJS/TEN overlap, and 94 TEN. The most common offending drugs were antibiotics (29.5% and anticonvulsants (24.1%. Carbamazepine, allopurinol, and penicillins were the most common single offending drugs (17.5%, 9.6%, and 7.2%. Chinese patent medicines accounted for 5.4%. There were 76 (45.8% patients receiving systemic steroid and intravenous immunoglobulin (IVIG in combination therapy, especially for TEN (80.3%, and others were treated with systemic steroids alone. Mortality rate of combination treatment comparing with steroid alone in TEN patients had no statistical significance. In conclusion, carbamazepine and allopurinol were the leading causative drugs for SJS/TEN in China. Combination of IVIG and steroids is a common treatment for TEN, but its efficacy in improving mortality needs further investigation.

  3. Contemporary perspectives in aesthetic theory: Steven Connor, Sianne Ngai and the edible world

    Directory of Open Access Journals (Sweden)

    Tom Lee

    2016-07-01

    Full Text Available This article interprets the work of cultural theorists Steven Connor and Sianne Ngai in terms of their efforts to reevaluate certain key presumptions of aesthetic theory that inherits the surprisingly resilient biases of the 18th century, in particular the work of Immanuel Kant and Edmund Burke. Focusing on the work of Ngai and Connor, I think through the implications this recent theory has for the previously peripheral position occupied by gustatory taste and the cultural objects and experiences it implicates. I discuss the possibility that ideas and examples drawn from the work of Connor and Ngai might form the basis for an alternative area of analysis that is better adapted to the peculiarities of gustatory taste and the culinary. In particular, I argue that the visceral element, which tends to accompany gustatory taste, ought to be interpreted in terms of its generative contribution to the creation of concepts through metaphor, rather than as a muddying influence that prevents clarity of discrimination. Similarly, the close relationship between the edible and the domestic is deserving of a more generous reading than is commonly found in aesthetic theory underwritten by the categories of the sublime and the beautiful.

  4. Genetic Markers and Danger Signals in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

    Directory of Open Access Journals (Sweden)

    Wen-Hung Chung

    2010-01-01

    Full Text Available Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN are life-threatening adverse reactions, which could be induced by a variety of drugs. It was proposed that human leukocyte antigen (HLA-restricted presentation of antigens (drugs or their metabolites to T lymphocytes initiates the immune reactions of SJS/ TEN. However, the genetic susceptibility and the exact pathogenesis were not clear until the recent studies. We first identified that HLA-B*1502 is strongly associated with carbamazepine (CBZ-induced SJS/TEN and HLA-B*5801 with allopurinol-SJS/TEN in Han Chinese. The same associations had been validated across different human populations. For the downstream danger signals, Fas-Fas ligand (FasL and perforin/granzyme B had been advocated as cytotoxic mediators for keratinocyte death in SJS/TEN. However, expression levels of these cytotoxic proteins from the skin lesions were too low to explain the distinct and extensive epidermal necrosis. Our recent study identified that the granulysin, a cytotoxic protein released from cytotoxic T cells or natural killer (NK cells, is a key mediator for disseminated keratinocyte death in SJS/TEN. This article aims to provide an overview of both of the genomic and immunologic perspectives of SJS/TEN. These studies give us a better understanding of the immune mechanisms, biomarkers for disease prevention and early diagnosis, as well as providing the therapeutic targets for the treatments of SJS/TEN.

  5. Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome.

    Science.gov (United States)

    Burkhart, Keith K; Abernethy, Darrell; Jackson, David

    2015-06-01

    Drug features that are associated with Stevens-Johnson syndrome (SJS) have not been fully characterized. A molecular target analysis of the drugs associated with SJS in the FDA Adverse Event Reporting System (FAERS) may contribute to mechanistic insights into SJS pathophysiology. The publicly available version of FAERS was analyzed to identify disproportionality among the molecular targets, metabolizing enzymes, and transporters for drugs associated with SJS. The FAERS in-house version was also analyzed for an internal comparison of the drugs most highly associated with SJS. Cyclooxygenases 1 and 2, carbonic anhydrase 2, and sodium channel 2 alpha were identified as disproportionately associated with SJS. Cytochrome P450 (CYPs) 3A4 and 2C9 are disproportionately represented as metabolizing enzymes of the drugs associated with SJS adverse event reports. Multidrug resistance protein 1 (MRP-1), organic anion transporter 1 (OAT1), and PEPT2 were also identified and are highly associated with the transport of these drugs. A detailed review of the molecular targets identifies important roles for these targets in immune response. The association with CYP metabolizing enzymes suggests that reactive metabolites and oxidative stress may have a contributory role. Drug transporters may enhance intracellular tissue concentrations and also have vital physiologic roles that impact keratinocyte proliferation and survival. Data mining FAERS may be used to hypothesize mechanisms for adverse drug events by identifying molecular targets that are highly associated with drug-induced adverse events. The information gained may contribute to systems biology disease models.

  6. Bicycles, Airplanes and Peter Pans: Flying Scenes in Steven Spielberg's Films

    Directory of Open Access Journals (Sweden)

    Emilio Audissino

    2014-10-01

    Full Text Available In Steven Spielberg's cinema the flight is a recurring theme. Flying scenes can be sorted into two classes: those involving a realistic flight – by aircraft – and those involving a magical flight – by supernatural powers. The realistic flight is influenced by the war stories of Spielberg's father – a radio man in U.S. Air-force during WWII – and it is featured in such films as Empire of the Sun (1987, Always (1989, and 1941 (1979. The magical flight is influenced by James M. Barries' character Peter Pan (Peter and Wendy, 1911, which is quoted directly in E.T. the Extraterrestrial (1982 and, above all, in Hook (1991, which is a sequel to Barrie's story. These two types of flying scenes are analysed as to their meanings, compared to the models that influenced them, and surveyed as to their evolution across Spielberg's films. A central case study is the episode The Mission from Amazing Stories (1985, in which the realistic and the magical flights overlap.

  7. A review of current practices and the future for deep well injection in the upper Miocene Stevens sand, Kern County, California

    International Nuclear Information System (INIS)

    Kiser, S.C.; Chenot, D.W.

    1991-01-01

    Waste-water disposal is a major concern of the petroleum business, especially because of complications associated with many produced-water surface-impoundment percolation facilities. In the San Joaquin Valley, California, the current environmental regulations protecting the potentially usable groundwaters are stringent. the Stevens has significant potential as a disposal zone that may offer considerable capacity when the project is designed using proper geologic and engineering studies. The Stevens sands are well known for their oil-producing capabilities, however, not much has been published regarding its suitability as a zone for deep well injection. Conditions that make the Stevens potentially suitable include (1) adequate confinement providing geologic separation from the groundwater sources in the basin, (2) storage capacity, and (3) large areal extent. Because the search for acceptable disposal options is becoming critical, the current class II disposal options is becoming critical, the current class II disposal activities in the Stevens sands were reviewed and the areas offering the greatest future potential were identified. The authors then discuss class II disposal projects in Stevens sands in the West Bellevue and Midway Sunset oil fields and estimate the ultimate basin-wide disposal capacity of the Stevens

  8. Fidelity, Adaptation, and Meta-commentary: The Case of Susan Orlean’s The Orchid Thief and Spike Jonze’s Adaptation

    Directory of Open Access Journals (Sweden)

    Victoria de Zwaan

    2017-12-01

    Full Text Available Abstract Susan Orlean’s The Orchid Thief has raised and defied questions about genre since its appearance in 1998. Though “research” and “facts” are at the foreground of the book, critics have described it by such terms as literary non-fiction, faction, personal journalism, and non-fiction novel because of its strong “literary,” that is narrative, characterological, thematic, and even philosophical, qualities. Struggling to make a faithful adaptation of this “simple” and “beautiful” book “about flowers” for film, Charlie Kaufman, the neurotic and anxious protagonist/screenwriter of Adaptation (2002, a fictionalized avatar of the real-life Charlie Kaufman, works through the wide range of possible generic and narrative adaptive possibilities that the book invites. The series of apparent false starts eventually get resolved, in a desperate attempt at creating closure, by way of the “Hollywood ending” that the screenwriter ostensibly despises and insists he will avoid. This paper engages the complex relationships between these two objects – The Orchid Thief and Adaptation – first, by providing some interpretive analysis of Orlean’s book and its potential adaptive possibilities, and second, by examining what happens to those possibilities in Adaptation. On my argument, the film refracts the book’s concerns into a meditation on the processes of reading, storytelling, and interpretation in the realm of explicit adaptation by way of metafiction, metalepsis, and other techniques associated with experimental narrative.

  9. Topical Treatment for Stevens - Johnson Syndrome and Toxic Epidermal Necrolysis: A Review

    Directory of Open Access Journals (Sweden)

    Schandra Purnamawati

    2016-08-01

    Full Text Available Background: Stevens - Johnson syndrome (SJS and Toxic Epidermal Necrolysis (TEN are currently regarded to be same disease entity which differs only in the extent and severity of epidermal sloughing. Both are potentially life-threatening mucocutaneous immunologic reaction, which are most frequently induced by drug consumption. The epithelial destruction of skin and mucosal membrane can cause both acute as well as chronic/ long term outcomes in term of  late sequelae during the course of the disease. Sequelae often occur during the late phase of SJS/TEN and become a significant problem due its chronicity and severe degree of impairment, which leads to deterioration of quality of life for the patients. This may prevented or decreased in terms of intensity if the patient’s received prompt and sufficient topical therapy, particularly in managing lesions on the mucosa of the eye, oral, and genital. Objective : This review underlines topical therapies which could be delivered for management of mucocutaneous lesions from SJS/ TEN, aimed to prevent late sequelae due to SJS – TEN in order to improve the life quality of SJS – TEN survivors. Conclusion: SJS/ TEN frequently lead to late sequeale which includes skin, ocular, oral, and genital involvement. These sequelaes are often severe and chonic. Thus, may cause significant decrease in quality of life of SJS/TEN survivors. It is therefore most important to detect them early in order to manage them adequately. To date, we still have an impression that the specific sequelae of SJS – TEN are often late diagnosed and insufficiently treated. Finally, we want to emphasize that for mucosal involvement in particular, such as ocular, genital and oral involvement, a careful topical treatment have to be taken into special consideration in order to prevent severe late sequelae. 

  10. Mucosal complications of modified osteo-odonto keratoprosthesis in chronic Stevens-Johnson syndrome.

    Science.gov (United States)

    Basu, Sayan; Pillai, Vinay Sukumara; Sangwan, Virender S

    2013-11-01

    To describe clinical outcomes of complications afflicting the autologous oral mucous membrane graft after modified osteo-odonto keratoprosthesis surgery in chronic Stevens-Johnson syndrome (SJS). Prospective case series. This study included 30 eyes of 30 patients with SJS-induced dry keratinized ocular surfaces; the patients underwent various stages of this procedure between August 2009 and February 2012. Mucosal complications were classified as either necrosis or overgrowth. Mucosal necrosis was managed according to a predesigned algorithm based on timing (pre- and postimplantation) and location (central or peripheral) of necrosis. Cases with mucosal overgrowth underwent mucosal debulking and trimming. Mucosal necrosis developed in 15 (50%) eyes and overgrowth in 4 (13.3%) eyes. Preimplantation necrosis (n = 7) was initially managed conservatively, but 2 eyes required free labial-mucous membrane grafting for persistent corneal exposure. Free labial-mucous membrane grafting was performed in all cases of postimplantation necrosis (n = 10), but 8 eyes required additional tarsal pedicle flaps (n = 6, for peripheral necrosis) or through-the-lid revisions (n = 2, for central necrosis). Debulking and trimming effectively managed all cases of mucosal overgrowth, but 3 eyes required repeat procedures. At 24.1 ± 6.5 months postimplantation, the keratoprosthesis was retained in all eyes, and the probability of maintaining 20/60 or better vision was similar in eyes with or without mucosal necrosis (86 ± 8.8% vs 80 ± 10.3%). Mucosal complications, especially necrosis, occurred commonly following modified osteo-odonto keratoprosthesis surgery in dry keratinized post-SJS eyes. The algorithm-based management approach described in this study was successful in treating these complications, retaining the prosthesis and preserving useful vision. Copyright © 2013 Elsevier Inc. All rights reserved.

  11. Improving mortality outcomes of Stevens Johnson syndrome/toxic epidermal necrolysis: A regional burns centre experience.

    Science.gov (United States)

    Nizamoglu, M; Ward, J A; Frew, Q; Gerrish, H; Martin, N; Shaw, A; Barnes, D; Shelly, O; Philp, B; El-Muttardi, N; Dziewulski, P

    2018-05-01

    Stevens Johnson Syndrome/toxic epidermal necrolysis (SJS/TEN) are rare, potentially fatal desquamative disorders characterised by large areas of partial thickness skin and mucosal loss. The degree of epidermal detachment that occurs has led to SJS/TEN being described as a burn-like condition. These patients benefit from judicious critical care, early debridement and meticulous wound care. This is best undertaken within a multidisciplinary setting led by clinicians experienced in the management of massive skin loss and its sequelae. In this study, we examined the clinical outcomes of SJS/TEN overlap & TEN patients managed by our regional burns service over a 12-year period. We present our treatment model for other burn centres treating SJS/TEN patients. A retrospective case review was performed for all patients with a clinical diagnosis of TEN or SJS/TEN overlap admitted to our paediatric and adult burns centre between June 2004 and December 2016. Patient demographics, percentage total body surface area (%TBSA), mucosal involvement, causation, severity of illness score (SCORTEN), length of stay and survival were appraised with appropriate statistical analysis performed using Graph Pad Prism 7.02 Software. During the study period, 42 patients (M26; F: 16) with TEN (n=32) and SJS/TEN overlap (n=10) were managed within our burns service. Mean %TBSA of cutaneous involvement was 57% (range 10-100%) and mean length of stay (LOS) was 27 days (range 1-144 days). We observed 4 deaths in our series compared to 16 predicted by SCORTEN giving a standardised mortality ratio (SMR) of 24%. Management in our burns service with an aggressive wound care protocol involving debridement of blistered epidermis and wound closure with synthetic and biological dressings seems to have produced benefits in mortality when compared to predicted outcomes. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

  12. Sedimentology of a surficial uranium deposit on North Flodelle Creek, Stevens County, Washington

    International Nuclear Information System (INIS)

    Macke, D.L.; Johnson, S.Y.; Otton, J.K.

    1985-01-01

    Surficial accumulations of uranium (up to 0.2 wt. % U/sub 3/O/sub 8/, dry basis) are currently forming in organic-rich, poorly drained sediments deposited in fluvial-lacustrine environments. Known occurrences are in northeastern Washington, northern Idaho, the Sierra Nevada, the Colorado Front Range, New Hampshire, and several areas in Canada. The first accumulation of this type to be mined is in postglacial sediments of a 10-acre boggy meadow along North Flodelle Creek in Stevens County, Washington. The meadow is flanked by hills of fine- to medium-grained two-mica quartz monzonite that are mantled by glacial drift of late Wisconsin age (about 18,000 to 11,500 yr B.P.). Relatively thick, hummocky deposits of this same glacial drift impede drainage at the lower end of the meadow. Following ice retreat, glacial sediments on the meadow floor were reworked by fluvial processes, and patches of organic-rich sediment may have formed in ice-melt depressions. About 6700 yr B.P., a blanket of Mazama ash from the Crater Lake eruption was deposited in the meadow. Shortly thereafter, a beaver dam across the lower end of the meadow further restricted drainage, and peat and organic mud accumulated in the pond behind the dam. The dam is preserved in the stratigraphic record as a sheet-like body of woody peat (with beaver-gnawed sticks) about 100m wide and 60 cm thick. After the gradual influx of sand and coarse silt had filled the pond, and the beavers had abandoned the site, fluvial deposition was reestablished

  13. Qualidade de vida dos pacientes portadores de síndrome de Stevens-Johnson

    Directory of Open Access Journals (Sweden)

    Nogueira Ruth

    2003-01-01

    Full Text Available OBJETIVO: Avaliar a qualidade de vida dos pacientes portadores de síndrome de Stevens-Johnson. MÉTODOS: Foram avaliados 14 pacientes com SSJ no período de 1998 e 1999 no Setor de Córnea do Departamento de Oftalmologia da UNIFESP. Empregou-se o questionário S. F. 36 - pesquisa em saúde. A pontuação indica melhor condição de saúde. A mesma avaliação foi repetida quatro vezes em intervalo de três meses. RESULTADOS: As médias das médias das 4 avaliações dos 14 pacientes apresentaram importante redução dos seus valores em todos os subitens do S.F. 36 (41,04±22,38 para aspectos físicos, 53,82±22,82 para aspectos sociais, 26,24±22,46 para aspectos emocionais, 34,95±25,45 para capacidade funcional, 42,03±31,85 para dor, 46,33±18,37 para vitalidade, 46,18±24,83 para saúde mental e 50,26±16,29 para saúde geral. CONCLUSÃO: O questionário S.F. 36 representa método adequado de avaliação de aspectos físicos e emocionais em pacientes com baixa de acuidade visual, que nos permitiu detectar comprometimento importante nas funções básicas dos pacientes com SSJ. Mais pacientes com maior tempo de seguimento são necessários para aprimorar a análise de qualidade de vida nesses pacientes e avaliar os efeitos do acompanhamento psicológico.

  14. "If you thought this story sour, sweeten it with your own telling" - a feminist poetics of rewriting in Susan Price's Ghost dance

    Directory of Open Access Journals (Sweden)

    Sanna Lehtonen

    2010-01-01

    Full Text Available The attempts to challenge conventional gendered discourses in children's fantasy have often resulted in feminist rewritings of earlier stories. Ghost dance (1994 by the English author Susan Price is a novel that reflects a specific feminist poetics of rewriting: metafictional passages highlight the constructedness of the narrative and at the end readers are invited to tell their own versions of the story. Moreover, the rewriting freely combines and recontextualises elements from different source texts and reformulates them to create a narrative that challenges conventional discourses of gender. While this poetics has an appeal from a feminist perspective, the play with cross-cultural intertexts and gender becomes more complex when the novel is examined in a postcolonialist framework in relation to ethnicity and the issue of cultural appropriation. Ghost dance is situated in a setting that has a real-world equivalent (Russia, involves characters that are identified with names of real-world ethnic groups (Lapps (Sámi, Russian, and mixes elements from Russian wonder tales, Nordic mythology and an Ojibwe legend. The novel does not aim at historical accuracy in its representations nor is it a direct retelling of any of the pre-texts but combines motifs, themes, names, characters and settings freely from each source. In this textual melting pot, the protagonist Shingebiss is, on one level, a revision of the witch Baba Yaga, but also described as a Lappish shaman with an Ojibwe name. To rewrite gendered discourses, certain elements from the pretexts are chosen and others left out – the question is, then, what effects does this recontextualisation have on the representation of ethnicity? Or, are the feminist rewriting strategies actually a form of cultural appropriation?

  15. Steven E. Miller and Dmitri V. Trenin, eds., The Russian Military: Power and Policy, Cambridge, MA: MIT Press, 2004.

    Directory of Open Access Journals (Sweden)

    Mikhail Tsypkin

    2005-10-01

    Full Text Available The Russian military largely went below the radar of Western interest after the disintegration of the Soviet Union.  More than a decade after the creation of the Armed Forces of the Russian Federation, they have become again the object of interest for scholars – this time, both Western and Russian, as demonstrated by the reviewed volume, whose editors assembled a group of extraordinarily knowledgeable experts from Russia and the West.  In his introduction, Steven Miller explains that the purp...

  16. Stereoselective synthesis of functionalized cyclic amino acid derivatives via a [2,3]-Stevens rearrangement and ring-closing metathesis.

    Science.gov (United States)

    Nash, Aaron; Soheili, Arash; Tambar, Uttam K

    2013-09-20

    Unnatural cyclic amino acids are valuable tools in biomedical research and drug discovery. A two-step stereoselective strategy for converting simple glycine-derived aminoesters into unnatural cyclic amino acid derivatives has been developed. The process includes a palladium-catalyzed tandem allylic amination/[2,3]-Stevens rearrangement followed by a ruthenium-catalyzed ring-closing metathesis. The [2,3]-rearrangement proceeds with high diastereoselectivity through an exo transition state. Oppolzer's chiral auxiliary was utilized to access an enantiopure cyclic amino acid by this approach, which will enable future biological applications.

  17. High Level Human Herpesvirus-6 Viremia Associated with onset of Stevens-Johnson Syndrome: Report of 2 Cases

    Science.gov (United States)

    Peppercorn, Amanda F.; Miller, Melissa B.; Fitzgerald, David; Weber, David J.; Groben, Pamela A.; Cairns, Bruce A.

    2015-01-01

    The pathogenesis of Stevens Johnson Syndrome (SJS) remains obscure but it has been associated with various infectious agents, including members of the Herpes virus family. We present the first report of high level human herpesvirus-6 (HHV-6) viremia at the onset of SJS suggesting a possible new association. This finding supports the need for further investigation into the possible relationship between HHV-6 and SJS which may illuminate the pathogenesis of SJS and bring us closer to achieving enhanced prevention and treatment of this rare disease. PMID:20182379

  18. Ernest Orlando Lawrence Awards Ceremony for 2011 Award Winners (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    International Nuclear Information System (INIS)

    Chu, Steven

    2012-01-01

    The winners for 2011 of the Department of Energy's Ernest Orlando Lawrence Award were recognized in a ceremony held May 21, 2012. Dr. Steven Chu and others spoke of the importance of the accomplishments and the prestigious history of the award. The recipients of the Ernest Orlando Lawrence Award for 2011 are: Riccardo Betti (University of Rochester); Paul C. Canfield (Ames Laboratory); Mark B. Chadwick (Los Alamos National Laboratory); David E. Chavez (Los Alamos National Laboratory); Amit Goyal (Oak Ridge National Laboratory); Thomas P. Guilderson (Lawrence Livermore National Laboratory); Lois Curfman McInnes (Argonne National Laboratory); Bernard Matthew Poelker (Thomas Jeffereson National Accelerator Facility); and Barry F. Smith (Argonne National Laboratory).

  19. Idufirma Silicon Valleyta / Susan Adams

    Index Scriptorium Estoniae

    Adams, Susan

    2014-01-01

    Tarkvarafirma Apprenda toodab teenindusplatvormi tarkvara, mis võimaldab klientidel luua ja hoida käigus uusi mobiilseid ja pilvetehnoloogiapõhiseid rakendusi. Oma töötajatele pakub odavaid elamispindu ja madalaid makse

  20. Honoring the work and life of Leroy C. Stevens. A symposium as part of the International Stem Cell Initiative Workshop.

    Science.gov (United States)

    Graham, Christopher F; Solter, Davor; Gearhart, John D; Nadeau, Joseph H; Knowles, Barbara B

    2016-01-01

    In 2016, a symposium was convened in Leroy C. Stevens' honor, in association with a meeting of the International Stem Cell Initiative (ISCI). ISCI, funded internationally, is composed of a group of ~100 scientists from many countries, under the leadership of Peter Andrews, who have worked together to characterize a significant number of human pluripotent stem cell lines, to monitor their genetic stability and their differentiation into mature cell types and tissues in vitro and in vivo. Those at the ISCI meeting puzzled through one of the thorniest problems in the therapeutic use of the differentiated derivatives of pluripotent stem cells for human therapy; namely, pluripotent stem cells can differentiate into any cell type in the adult organism, but they also have the capacity for unlimited self-renewal, hence if mutated they may have tumorigenic potential. The meeting considered how these cells might become genetically or epigenetically abnormal and how the safety of these cells for human therapeutic uses could be assessed and assured. The symposium was an opportunity to pay tribute to Leroy Stevens and to the basic science origins of this newest aspect of regenerative medicine. It was a time to reflect on the past and on how it can influence the future of our field.

  1. Review of The Joy of x: A Guided Tour of Math, from One to Infinity by Steven Strogatz

    Directory of Open Access Journals (Sweden)

    Michael T. Catalano

    2014-07-01

    Full Text Available Strogatz, Steven. The Joy of x: A Guided Tour of Math, from One to Infinity, (New York, NY, Houghton Mifflin Harcourt, 2012. 316 pp. ISBN 978-0-547-51765-0 The Joy of x: A Guided Tour of Math, from One to Infinity, by Steven Strogatz, is an engaging and example-filled argument for mathematics as a valuable and enjoyable activity. The thirty chapters are divided into six parts, entitled Numbers, Relationships, Shapes, Change, Data, and Frontiers. The discussion ranges from intuitive explanations of basic concepts such as place value, the four arithmetic operations, percentage increase and decrease, and solving equations, to “higher” levels of mathematics such as calculus, probability and statistics, group theory, and the nature of infinity. As in John Allen Paulos’ work, Beyond Numeracy, the chapters are short and punchy, and they can be read independently. While the book is not specifically devoted to numeracy, several chapters, especially those in Part Five on Data, address ideas and examples relevant to quantitative literacy.

  2. Areas of Agreement and Disagreement Regarding Ponderosa Pine and Mixed Conifer Forest Fire Regimes: A Dialogue with Stevens et al.

    Directory of Open Access Journals (Sweden)

    Dennis C Odion

    Full Text Available In a recent PLOS ONE paper, we conducted an evidence-based analysis of current versus historical fire regimes and concluded that traditionally defined reference conditions of low-severity fire regimes for ponderosa pine (Pinus ponderosa and mixed-conifer forests were incomplete, missing considerable variability in forest structure and fire regimes. Stevens et al. (this issue agree that high-severity fire was a component of these forests, but disagree that one of the several sources of evidence, stand age from a large number of forest inventory and analysis (FIA plots across the western USA, support our findings that severe fire played more than a minor role ecologically in these forests. Here we highlight areas of agreement and disagreement about past fire, and analyze the methods Stevens et al. used to assess the FIA stand-age data. We found a major problem with a calculation they used to conclude that the FIA data were not useful for evaluating fire regimes. Their calculation, as well as a narrowing of the definition of high-severity fire from the one we used, leads to a large underestimate of conditions consistent with historical high-severity fire. The FIA stand age data do have limitations but they are consistent with other landscape-inference data sources in supporting a broader paradigm about historical variability of fire in ponderosa and mixed-conifer forests than had been traditionally recognized, as described in our previous PLOS paper.

  3. Areas of Agreement and Disagreement Regarding Ponderosa Pine and Mixed Conifer Forest Fire Regimes: A Dialogue with Stevens et al.

    Science.gov (United States)

    Odion, Dennis C; Hanson, Chad T; Baker, William L; DellaSala, Dominick A; Williams, Mark A

    2016-01-01

    In a recent PLOS ONE paper, we conducted an evidence-based analysis of current versus historical fire regimes and concluded that traditionally defined reference conditions of low-severity fire regimes for ponderosa pine (Pinus ponderosa) and mixed-conifer forests were incomplete, missing considerable variability in forest structure and fire regimes. Stevens et al. (this issue) agree that high-severity fire was a component of these forests, but disagree that one of the several sources of evidence, stand age from a large number of forest inventory and analysis (FIA) plots across the western USA, support our findings that severe fire played more than a minor role ecologically in these forests. Here we highlight areas of agreement and disagreement about past fire, and analyze the methods Stevens et al. used to assess the FIA stand-age data. We found a major problem with a calculation they used to conclude that the FIA data were not useful for evaluating fire regimes. Their calculation, as well as a narrowing of the definition of high-severity fire from the one we used, leads to a large underestimate of conditions consistent with historical high-severity fire. The FIA stand age data do have limitations but they are consistent with other landscape-inference data sources in supporting a broader paradigm about historical variability of fire in ponderosa and mixed-conifer forests than had been traditionally recognized, as described in our previous PLOS paper.

  4. Detection of an ylide intermediate in the electrochemically-induced Stevens rearrangement of an ammonium salt by in situ UV–vis spectroelectrochemistry

    International Nuclear Information System (INIS)

    Capobianco, Amedeo; Caruso, Tonino; Palombi, Laura; Peluso, Andrea

    2013-01-01

    Highlights: ► Mechanistic insights of the electro-induced Stevens rearrangement are provided. ► The reduction of PhCOCH 2 N + (CH 3 ) 2 CH 2 Ph is ascribed to a one-electron transfer process. ► An electrogenerated ammonium ylide has been detected by UV-spectroelectrochemistry. -- Abstract: The electrochemically-induced Stevens rearrangement of 2-(benzyldimethyl)ammonium acetophenone has been investigated by in situ UV–vis spectroelectrochemistry. Voltammetric analysis and absorption spectra recorded during the potentiostatic reduction indicate that the reaction proceeds via a one-electron transfer with a Platinum cathode and generation of an ammonium ylide intermediate

  5. Organizational Heritage and Entrepreneurship: Steven Klepper’s Theories Reflected in the Emergence and Growth of the Plastic Molds Industry in Portugal

    NARCIS (Netherlands)

    Costa, Carla

    2015-01-01

    This paper reviews the history of the emergence of the molds and plastics industries in Portugal, finding that this history fits nicely with the accounts—originally proposed in Steven Klepper’s various works—of new industries emerging from older, related industries, and regional clusters emerging

  6. Från outsiderfilmmakare till etablerad indieregissör : David Lynch, Jim Jarmusch och Steven Soderbergh

    OpenAIRE

    Simberg, Maximilian

    2014-01-01

    Det här arbetet behandlar kreativ frihet och konstnärligt oberoende i filmskapande, utgående från begreppet independent film och regissörerna David Lynch, Jim Jarmusch och Steven Soderbergh. Den centrala frågeställningen är hur det har varit möjligt för en filmkonstnär att uppnå konstnärligt oberoende och samtidigt ha en långlivad och framgångsrik karriär. Arbetets fokus ligger på de tre regissörernas genombrottsfilmer; Eraserhead, Stranger Than Paradise och sex, lies, and videotape, och förs...

  7. Síndrome de Stevens-Johnson e necrólise epidérmica tóxica

    OpenAIRE

    Coelho, Inês Dionísio

    2013-01-01

    Trabalho final de mestrado integrado em Medicina (Dermatologia), apresentado à Faculdade de Medicina da Universidade de Coimbra. A Síndrome de Stevens-Johnson (SSJ) e a necrólise epidérmica tóxica (NET) são reacções mucocutâneas raras consideradas emergências médicas, podendo tornar-se fatais. Constituem dois extremos do mesmo espectro clínico das reacções cutâneas severas adversas a fármacos com necrose epidérmica, diferindo apenas na extensão do descolamento epidérmico. A gra...

  8. Stevens Johnson syndrome, toxic epidermal necrolysis and SJS-TEN overlap: A retrospective study of causative drugs and clinical outcome

    Directory of Open Access Journals (Sweden)

    Sharma Vinod

    2008-01-01

    Full Text Available Background and Aims: Stevens Johnson syndrome (SJS, toxic epidermal necrolysis (TEN and SJS-TEN overlap are serious adverse cutaneous drug reactions. Drugs are often implicated in these reactions. Methods: A retrospective analysis of inpatients′ data with these dermatological diagnoses were carried out for three years, to study the causative drugs, clinical outcome, and mortality in these conditions. Results: Thirty patients (15 TEN, nine SJS-TEN overlap, and six SJS were admitted. In 21 cases, multiple drugs were implicated whereas single drugs were responsible in nine. Anticonvulsants (35.08% were the most commonly implicated drugs followed by antibiotics (33.33% and NSAIDS (24.56%. Twenty-five patients recovered whereas five died (four TEN, one SJS-TEN overlap. Conclusion: Anticonvulsants, antibiotics and NSAIDs were the most frequently implicated drugs. TEN causes higher mortality than both SJS and SJS-TEN overlap.

  9. Association of HLA-BFNx011502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians

    Directory of Open Access Journals (Sweden)

    Mehta Timir

    2009-01-01

    Full Text Available Background: Stevens-Johnson Syndrome (SJS and toxic epidermal necrolysis are severe cutaneous reactions caused by certain drugs, including antiepileptic carbamazepine. A strong association has been reported between human leucocyte antigen (HLA-BFNx011502 and carbamazepine-induced SJS in Han Chinese patients. European studies suggested that HLA-BFNx011502 is not a universal marker but is ethnicity-specific for Asians. Aim: To study the association between HLA-BFNx011502 and carbamazepine-induced SJS in Indian patients. Methods: Eight individuals who fulfilled the diagnostic criteria of SJS induced by carbamazepine were identified and HLA-B molecular typing was performed. HLA-B genotyping was carried out by polymerase chain reaction using sequence-specific primers. Results: Out of eight patients studied for genotype, six patients were found to have the HLA-BFNx011502 allele. Conclusion: This study suggests an association between HLA-BFNx011502 and carbamazepine-induced SJS in Indian patients.

  10. Steven Pinker. The Better Angels of Our Nature. Why violence has declined. Viking Adult, New York, 2011, 832 p.

    OpenAIRE

    Jairo Antonio Melo Flórez

    2011-01-01

    Aunque ya es una tesis bastante aceptada por los historiadores y sociólogos, la posibilidad de que, al contrario de la creencia popular, vivamos en tal vez una de las épocas más pacíficas de la historia es aún controvertida, más aún cuando llega un trabajo de una de las figuras públicas de la academia como es el profesor de Harvard Steven Pinker. Sin embargo, Pinker se había dedicado a psicología cognitiva y ganó fama al presentar al lenguaje como un instinto de la humanidad, y más aún al pre...

  11. Steven Pinker. The Better Angels of Our Nature. Why violence has declined. Viking Adult, New York, 2011, 832 p.

    Directory of Open Access Journals (Sweden)

    Jairo Antonio Melo Flórez

    2011-05-01

    Full Text Available Aunque ya es una tesis bastante aceptada por los historiadores y sociólogos, la posibilidad de que, al contrario de la creencia popular, vivamos en tal vez una de las épocas más pacíficas de la historia es aún controvertida, más aún cuando llega un trabajo de una de las figuras públicas de la academia como es el profesor de Harvard Steven Pinker. Sin embargo, Pinker se había dedicado a psicología cognitiva y ganó fama al presentar al lenguaje como un instinto de la humanidad, y más aún al presentar sus resultados en libros dirigidos al público en general, algo bastante común entre los científicos norteamericanos.

  12. Er gulvet grim og skummel, så ring til Hummel

    DEFF Research Database (Denmark)

    Brügger, Niels

    for at komme med et bud på. Bogen bygger på over 300 slogans, som forfatteren har indsamlet gennem flere år. Niels Brügger er lektor i medievidenskab ved Institut for Informations- og Medievidenskab, Aarhus Universitet. Til daglig forsker han i internettets historie — de sjove slogans er en hobby....

  13. Comparison of the U-233 dog data of Stevens et al. with uranium retention functions in ICRP Publication 30 and a 3-compartment mammillary model for uranium

    International Nuclear Information System (INIS)

    Bernard, S.R.

    1983-01-01

    Stevens measured the distribution, retention, and excretion of U-233 in seven beagles each given a single injection of U-233 citrate [2.8 μCi/kg U-233 (VI) (approx.3 mg/dog)]. These data, when plotted together with results obtained with the ICRP (Pub. 30) retention functions for purposes of comparison, are seen to differ only slightly from the ICRP-30 model. The number of transformations in the body, over a fifty-year period agree within a factor of 2. A three-compartment mammillary model has been parameterized from the data of Stevens by the method of Bernard. Retention in tissues of the body is represented by a linear combination of three compartments. The data plots for the dogs and ICRP-30 model will be presented and discussed together with the three compartment mammillary model for U-233 retention, distribution, and excretion. 3 figs., 2 tabs

  14. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures

    OpenAIRE

    Schneider, Jeremy A.; Cohen, Philip R.

    2017-01-01

    Introduction Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN. Purpose The scientific literature pertaining to SJS and TEN (subsequently referred to as SJS/TEN) is summarized and assessed. In addition, an interventional approach for the clinician is provided. Methods PubMed was searched with the key words: cortic...

  15. Characterization of fish sauce aroma-impact compounds using GC-MS, SPME-Osme-GCO, and Stevens' power law exponents.

    Science.gov (United States)

    Pham, A J; Schilling, M W; Yoon, Y; Kamadia, V V; Marshall, D L

    2008-05-01

    The objectives of this study were to characterize volatile compounds and to determine the characteristic aromas associated with impact compounds in 4 fish sauces using solid-phase micro-extraction, gas chromatography-mass spectrometry, Osme, and gas chromatography olfactometry (SPME-Osme-GCO) coupled with Stevens' Power Law. Compounds were separated using GCMS and GCO and were identified with the mass spectral database, aroma perceived at the sniffing port, retention indices, and verification of compounds by authentic standards in the GCMS and GCO. Aromas that were isolated and present in all 4 fish sauce samples at all concentrations included fishy (trimethylamine), pungent and dirty socks (combination of butanoic, pentanoic, hexanoic, and heptanoic acids), cooked rice and buttery popcorn (2,6-dimethyl pyrazine), and sweet and cotton candy (benzaldehyde). All fish sauces contained the same aromas as determined by GCO and GCMS (verified using authentic standard compounds), but the odor intensity associated with each compound or group of compounds was variable for different fish sauce samples. Stevens' Power Law exponents were also determined using this analytical technique, but exponents were not consistent for the same compounds that were found in all fish sauces. Stevens' Power Law exponents ranged from 0.14 to 0.37, 0.24 to 0.34, 0.09 to 0.21, and 0.10 to 0.35 for dirty socks, fishy, buttery popcorn, and sweet aromas, respectively. This demonstrates that there is variability in Stevens' Power Law exponents for odorants within fish sauce samples.

  16. Q&A with Steven Spencer: Speaker in the Women and STEM Series Talks About How He Became Interested in Studying Psychology, Dissonance, and Stereotype Threat

    OpenAIRE

    Hooker, Courtney

    2011-01-01

    As I talked with Steven Spencer, Professor at the University of Waterloo and a groundbreaking researcher in the field of stereotype threat, I was impressed by his kind demeanor and effective speaking style. He shared information about his academic career, advice for graduate students as well as discussing this research on how to dismantle the negative stereotypes that inhibit women’s progression in science, technology, engineering, and math fields (STEM).

  17. Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN): could retinoids play a causative role?

    Science.gov (United States)

    Mawson, Anthony R; Eriator, Ike; Karre, Sridhar

    2015-01-12

    Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are overlapping manifestations on a spectrum of acute drug-induced conditions associated with severe blistering, skin peeling, and multi-organ damage. TEN is an eruption resembling severe scalding, with ≥30% skin detachment. SJS is a mild form of TEN, characterized histologically by epidermal keratinocyte apoptosis with dermo-epidermal separation and extensive small blisters with <10% body surface skin detachment. The syndrome can be induced by numerous medications and typically occurs 1-4 weeks after the initiation of therapy. Granulysin is found in the lesions of patients with SJS/TEN and plays a significant pathogenic role in the condition, but the overall mechanisms linking medications, granulysin, and disease manifestations remain obscure. This paper reviews evidence suggesting that the different medications implicated in SJS/TEN have the common property of interacting and synergizing with endogenous retinoids (vitamin A and its congeners), in many instances causing the latter to accumulate in and damage the liver, the main storage organ for vitamin A. It is hypothesized that liver damage leads to the spillage of toxic retinoid compounds into the circulation, resulting in an endogenous form of hypervitaminosis A and cytotoxicity with widespread apoptosis, mediated by granulysin and recognized as SJS/TEN. Subject to testing, the model suggests that symptom worsening could be arrested at onset by lowering the concentration of circulating retinoids and/or granulysin via phlebotomy or plasmapheresis or by pharmacological measures to limit their expression.

  18. “Inspired by real events”—Media (and Memory in Steven Spielberg’s MUNICH (2005

    Directory of Open Access Journals (Sweden)

    Thomas Nachreiner

    2016-02-01

    Full Text Available Steven Spielberg’s 2005 film Munich tells the story of an Israeli counter-terrorist team in the aftermath of the hijacking and massacre at the Olympic Games in 1972. The film spawned broad discussion about its historical accuracy and its political standpoint. While criticism primarily focused on the historiographical representation of the actions depicted, this paper analyzes in two steps the genuinely filmic mode of historical representation ofMunich. First, the analysis discusses the interplay of two conflicting narrative strategies that negotiate the character development with the political struggle. And second, analysis focuses on the two formal devices at the core of the narrative conflict: The reflexive framing of television in the depiction of the Munich massacre as a traumatic media event and the excessive transformation of its memory in a series of flashbacks. Such elaboration of the narrative and formal strategies reveals the implicit historiographical structures of the film and suggests that the notion of ‘cultural trauma’ serves as the preferential—but problematic—template in telling the history of terrorism and violence.

  19. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis--A Comprehensive Review and Guide to Therapy. I. Systemic Disease.

    Science.gov (United States)

    Kohanim, Sahar; Palioura, Sotiria; Saeed, Hajirah N; Akpek, Esen K; Amescua, Guillermo; Basu, Sayan; Blomquist, Preston H; Bouchard, Charles S; Dart, John K; Gai, Xiaowu; Gomes, José A P; Gregory, Darren G; Iyer, Geetha; Jacobs, Deborah S; Johnson, Anthony J; Kinoshita, Shigeru; Mantagos, Iason S; Mehta, Jodhbir S; Perez, Victor L; Pflugfelder, Stephen C; Sangwan, Virender S; Sippel, Kimberly C; Sotozono, Chie; Srinivasan, Bhaskar; Tan, Donald T H; Tandon, Radhika; Tseng, Scheffer C G; Ueta, Mayumi; Chodosh, James

    2016-01-01

    The intent of this review is to comprehensively appraise the state of the art with regard to Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), with particular attention to the ocular surface complications and their management. SJS and TEN represent two ends of a spectrum of immune-mediated, dermatobullous disease, characterized in the acute phase by a febrile illness followed by skin and mucous membrane necrosis and detachment. The widespread keratinocyte death seen in SJS/TEN is rapid and irreversible, and even with early and aggressive intervention, morbidity is severe and mortality not uncommon. We have divided this review into two parts. Part I summarizes the epidemiology and immunopathogenesis of SJS/TEN and discusses systemic therapy and its possible benefits. We hope this review will help the ophthalmologist better understand the mechanisms of disease in SJS/TEN and enhance their care of patients with this complex and often debilitating disease. Part II (April 2016 issue) will focus on ophthalmic manifestations. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Síndrome de Stevens Johnson, presentación de un caso en edad pediátrica

    Directory of Open Access Journals (Sweden)

    Maritza Morales Solís

    2015-11-01

    Full Text Available El síndrome de Stevens-Johnson (SSJ es una variante severa del eritema multiforme, consistente en una reacción de hipersensibilización que afecta piel y mucosa, además de otros órganos internos, y que se manifiesta con lesiones en zonas genitales, bucales y cutáneas, es idiopático en el 50% de los casos, generalmente producido por alergia a medicamentos. La muerte sobreviene en el 5-15% de los casos sin tratar. El riesgo de recurrencia es del 37% o más.  Al Hospital Pediátrico Provincial Docente “Mártires de Las Tunas”  fue  traído un niño de seis años  de edad, que tras el uso del Sulfaprín comenzó con lesiones que afectaban la piel y  todas las mucosas, además de toma del estado general. Inmediatamente fue admitido en la Unidad de Cuidados  Intensivos Pediátricos, donde fueron tomadas medidas que incluyeron supresión del agente causal,  corticoterapia endovenosa, antibioticoterapia endovenosa, tratamiento de las lesiones, vigilancia del balance hidromineral y atención oftalmológica, respondiendo favorablemente. Se presenta el caso, por ser una enfermedad poco frecuente y de muy mal pronóstico.

  1. The Pitfalls of Picturing Atlantic Slavery: Steven Spielberg’s Amistad vs Guy Deslauriers’s The Middle Passage

    Directory of Open Access Journals (Sweden)

    Lars Eckstein

    2011-04-01

    On the one hand, the arts are particularly called for in this situation to fill the documentary gaps and silences through acts of experiment and imagination, and they may indeed have a redemptive effect by offering, in Hayden White’s terms, successful ‘emplotments’ of a traumatic past. One the other hand, this redemptive potential simultaneously poses a serious ethical challenge: As Theodor W. Adorno has warned with reference to the Holocaust, it is precisely by making ‘sense’ of human suffering, and by making accessible to the ‘senses’ what is utterly senseless and incomprehensible, that injustice may be done to the victims. In this paper, I will try to illustrate this problematic by looking at two recent films that have attempted to represent the horrors of the middle passage – Steven Spielberg’s canonical Amistad (a terrible failure, in my view, and Guy Deslauriers’ film The Middle Passage [Passage du Milieu]. Based on a script by the Martiniquean novelist and poet Patrick Chamoiseau, the latter example uses an aesthetic approach which may point at a way out of the dilemma outlined above.

  2. Nine years of a single referral center management of Stevens-Johnson syndrome and toxic epidermal necrolysis (Lyell's syndrome).

    Science.gov (United States)

    Monteiro, Diana; Egipto, Paula; Barbosa, Julia; Horta, Ricardo; Amarante, Jose; Silva, Pedro; Silva, Alvaro

    2017-06-01

    Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) corresponds to a rare and acute life-threatening mucocutaneous reactions characterized by extensive necrosis and epidermal detachment. There are no efficacious pharmaceutical interventions proven through large clinical trials. We sought to study clinical cases admitted in our institution in order to determine which drugs and medical comorbidities or treatments impacted the mortality. In a retrospective study over 9 years we evaluated all patients presenting biopsy-proven SJS or TEN for age, gender, total body surface area involved, causing agents, SCORTEN score, blood transfusion, steroid administration, intubation, length of intensive care stay and death rate. Statistical analysis was done using SPSS statistical software. The highest incidence of SJS and TEN was in age group of 71-80 years. Of the 30 patients, 30% died from SJS/TEN, mainly due sepsis. For each subgroup SJS/TEN overlap had the highest mortality. The highest mortality was from antibiotic treatment as causing agent. Step-wise regression analysis identified mechanical ventilation requirement and age over 65 years as mortality high-risk factors. The most crucial interventions are discontinuation of the offending drug and prompt referral to a burn unit, which helps in early diagnosis and decrease mortality in these diseases. When SJS/TEN is caused by antibiotics suspicion of developing fatal sepsis should be high, independently of patients' medical condition.

  3. Inter population variability of frost-resistance in provenances of scot pines (Pinusylvestris L.R. hamata Steven in Turkey

    Directory of Open Access Journals (Sweden)

    Özel Halil Barış

    2016-01-01

    Full Text Available Frost-resistance variability of Scotch pine (Pinus sylvestris L. var. hamata Steven seedlings grown in nurseries conditions, originated from 10 provenances, have been analyzed. The provenances from Black Sea region, Central Anatolian region and Eastern Anatolian region in Turkey have been used in selection of seed zones. The results of frost-resistance tests indicated a strong relationship of implemented freezing degrees with injury degrees of Scotch pine needles and photosynthetic productivities. On the other hand, another significant relationship has been determined between chlorophyll fluorescence and ion leakage methods (r=-0.801. This result shows that those two methods can be safely used in determining the damages due to low temperatures. In frost resistance tests, Scotch pine seedlings from different provenances have been frozen at -10, -20, -30 and -40°C. According to the Duncan test results, it has been determined that damage increased as temperature decreased. The damage level at -10°C implementation is 3.5% which can be tolerated by plants. But when the temperature has been decreased to -20°C, the level of damage has increased to 51.25%. As a result of photosynthetic analyses in this phase, it has been determined that there is a statistically significant relationship between provenances and temperature levels. Under the light of those findings, they have determined that the photosynthetic productivity has significantly decreased at temperatures between -20°C and -40°C. This situation conforms to injury index values determined in this study. As a result of injury index and photosynthetic productivity tests used for determining the damage after frost-resistance tests, it has been determined that the provenances of Amasya-Kunduz, Bolu-Aladağ, Düzce-Yığılca, Samsun-Vezirköprü and Eskişehir-Çatacık are more sensitive to frost than other provenances.

  4. Survey of Nonprescription Medication and Antibiotic Use in Patients with Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Overlap Syndrome

    Directory of Open Access Journals (Sweden)

    Katherine J. Sullivan

    2018-02-01

    Full Text Available Stevens-Johnson syndrome (SJS, toxic epidermal necrolysis (TEN, and overlap syndrome (SJS-TEN are rare, serious skin and mucosa break-down conditions frequently associated with antibiotic use. The role of nonprescription medications alone, or in combination with antibiotics in triggering SJS/TEN, is largely unknown. This study summarized data collected from patient surveys about nonprescription and antibiotic use prior to a SJS/TEN diagnosis. The survey was administered online to members of the U.S. SJS Foundation who had been diagnosed with SJS/TEN or were the parent of a child who had been diagnosed with SJS/TEN. Respondents were asked about nonprescription medications taken within the year before diagnosis, and the approximate point in time before diagnosis that they had taken them. They were also asked about specific prescription medications, including antibiotics, that they took before diagnosis. An estimated 4500 patients received an invitation to complete the survey. 251 patients completed it, resulting in a response rate of 5.6%. The mean age of respondents was 43 years (SD (standard deviation = 17.3 and 70% were female. 32.3% of respondents indicated that a prescription antibiotic triggered their reaction. 14.1% indicated a nonprescription medication had triggered their SJS/TEN, and 18.1% said a nonprescription medication may have triggered their SJS/TEN. 85.5% of respondents said they took a nonprescription medication within three months of their SJS/TEN diagnosis. Of those respondents who reported that an antibiotic triggered their SJS/TEN, 35.2% reported taking a nonprescription medication within the three months prior to their diagnosis. This survey captured valuable information about nonprescription and antibiotic use in SJS/TEN patients. It is important for future studies to estimate the impact of antibiotics on SJS/TEN, and account for nonprescription medication use in that relationship.

  5. Stevens-Johnson syndrome and toxic epidermal necrolysis in childhood-onset systemic lupus erythematosus patients: a multicenter study

    Directory of Open Access Journals (Sweden)

    Ana Paula Sakamoto

    2017-07-01

    Full Text Available Objective: To assess Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN in a large population of childhood-onset systemic lupus erythematosus (cSLE patients. Methods: Multicenter study including 852 cSLE patients followed in Pediatric Rheumatology centers in São Paulo, Brazil. SJS was defined as epidermal detachment below 10% of body surface area (BSA, overlap SJS-TEN 10-30% and TEN greater than 30% of BSA. Results: SJS and TEN was observed in 5/852 (0.6% cSLE female patients, three patients were classified as SJS and two patients were classified as overlap SJS-TEN; TEN was not observed. The mean duration of SJS and overlap SJS-TEN was 15 days (range 7-22 and antibiotics induced four cases. Regarding extra-cutaneous manifestations, hepatomegaly was observed in two cSLE patients, nephritis in two and neuropsychiatric involvement and conjunctivitis were observed respectively in one patient. Hematological involvement included lymphopenia in four, leucopenia in three and thrombocytopenia in two patients. The mean SLEDAI-2K score was 14.8 (range 6-30. Laboratory analysis showed low C3, C4 and/or CH50 in two patients and the presence of anti-dsDNA autoantibody in two patients. One patient had lupus anticoagulant and another one had anticardiolipin IgG. All patients were treated with steroids and four needed additional treatment such as intravenous immunoglobulin in two patients, hydroxychloroquine and azathioprine in two and intravenous cyclophosphamide in one patient. Sepsis was observed in three cSLE patients. Two patients required intensive care and death was observed in one patient. Conclusion: Our study identified SJS and overlap SJS-TEN as rare manifestations of active cSLE associated with severe multisystemic disease, with potentially lethal outcome.

  6. Milliste plaanidega lähed vastu uuele õppeaastale? / Triinu Lepp, Gleb Tšurbanov, Erik Paemurru, Steven Huang...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad hariduskolleegiumi algkooli 3. klassi õpilane Egert, prantsuse lütseumi 12. klassi õpilane Triinu Lepp, Sillamäe kutsekooli 3. kursuse õpilane Gleb Tšurbanov, Tallinna reaalkooli 11. klassi õpilane Erik Paemurru, Toronto Crescenti keskkooli õpilane Steven Huang, kunstiakadeemia muinsuskaitse- ja restaureerimisosakonna õppejõud Jaan Tamm, Tartu Miina Härma gümnaasiumi 2. a klassi õpilane Erki Külaots, Tallinna 21. kooli 11. klassi õpilane Sander Kaur ja Tapa gümnaasiumi 7. klassi õpilane Evelin Orgse

  7. Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital

    OpenAIRE

    Susheera Chatproedprai; Vanvara Wutticharoenwong; Therdpong Tempark; Siriwan Wananukul

    2018-01-01

    Aim. To determine the probable causative factors, clinical features, and treatment outcomes of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS-TEN overlap in children. Methods. A 20-year database review of all children diagnosed with SJS/TEN/SJS-TEN overlap at the King Chulalongkorn Memorial Hospital, Thailand. Results. 36 patients (M : F, 16 : 20) with the mean age of 9.2±4.0 years were identified. There were 20 cases of SJS, 4 cases of SJS-TEN overlap, and 12 cases...

  8. Neutrophil Collagenase, Gelatinase and Myeloperoxidase in Tears of Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid Patients

    Science.gov (United States)

    Arafat, Samer N.; Suelves, Ana M.; Spurr-Michaud, Sandra; Chodosh, James; Foster, C. Stephen; Dohlman, Claes H.; Gipson, Ilene K.

    2013-01-01

    Objective To investigate the levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in tears of patients with Stevens-Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP). Design Prospective non-interventional cohort study. Participants Four SJS patients (7 eyes), 19 OCP patients (37 eyes) and 20 post-phacoemulsification healthy controls (40 eyes). Methods Tear washes were collected from all patients and were analyzed for levels of MMP-2, -3, -7, -8, -9, -12, MPO and TIMP-1 using multi-analyte bead-based enzyme-linked immunosorbent assays (ELISA). Total MMP activity was determined using a fluorimetric assay. Correlation studies were performed between the various analytes within study groups. Main Outcome Measures Levels of MMP-2, -3, -7, -8, -9, -12, MPO and TIMP-1 (in ng/µg protein), total MMP activity (in relative fluorescent units/min/µg protein) in tears, MMP-8/TIMP-1, MMP-9/TIMP-1 ratios and the correlations between MMP-8 and MMP-9 and each MMP and MPO. Results MMP-8, MMP-9 and MPO levels were significantly elevated in SJS and OCP tears (SJS > OCP) when compared to controls. MMP activity was highest in SJS while OCP and controls showed lower and similar activities. TIMP-1 levels were decreased in SJS and OCP when compared to controls with OCP levels reaching significance. MMP-8/TIMP-1 and MMP-9/TIMP-1 ratios were markedly elevated in SJS and OCP tears (SJS > OCP) when compared to controls. Across all study groups, MMP-9 levels correlated strongly with MMP-8 and MPO levels and MMP-8 correlated with MPO but did not reach significance in SJS. There was no relationship between MMP-7 and MPO. Conclusions Since MMP-8 and MPO are produced by inflammatory cells, particularly neutrophils, the correlation data indicate that they may be the common source of elevated enzymes including MMP-9 in SJS and OCP tears. Elevated MMP/TIMP ratios and MMP activity suggest an imbalance in tear MMP regulation

  9. Neutrophil collagenase, gelatinase, and myeloperoxidase in tears of patients with stevens-johnson syndrome and ocular cicatricial pemphigoid.

    Science.gov (United States)

    Arafat, Samer N; Suelves, Ana M; Spurr-Michaud, Sandra; Chodosh, James; Foster, C Stephen; Dohlman, Claes H; Gipson, Ilene K

    2014-01-01

    To investigate the levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in tears of patients with Stevens-Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP). Prospective, noninterventional cohort study. Four SJS patients (7 eyes), 19 OCP patients (37 eyes), and 20 healthy controls who underwent phacoemulsification (40 eyes). Tear washes were collected from all patients and were analyzed for levels of MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MPO, and TIMP-1 using multianalyte bead-based enzyme-linked immunosorbent assays. Total MMP activity was determined using a fluorometric assay. Correlation studies were performed between the various analytes within study groups. Levels of MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MPO, and TIMP-1 (in nanograms per microgram of protein) and total MMP activity (in relative fluorescent units per minute per microgram of protein) in tears; MMP-8-to-TIMP-1 ratio; MMP-9-to-TIMP-1 ratio; and the correlations between MMP-8 and MMP-9 and both MMP and MPO. MMP-8, MMP-9, and MPO levels were elevated significantly in SJS and OCP tears (SJS>OCP) when compared with controls. The MMP activity was highest in SJS patients, whereas OCP patients and controls showed lower and similar activities. The TIMP-1 levels were decreased in SJS and OCP patients when compared with those in controls, with levels in OCP patients reaching significance. The MMP-8-to-TIMP-1 and MMP-9-to-TIMP-1 ratios were markedly elevated in SJS and OCP tears (SJS>OCP) when compared with those of controls. Across all study groups, MMP-9 levels correlated strongly with MMP-8 and MPO levels, and MMP-8 correlated with MPO, but it did not reach significance in SJS patients. There was no relationship between MMP-7 and MPO. Because MMP-8 and MPO are produced by inflammatory cells, particularly neutrophils, the correlation data indicate that they may be the common source of elevated enzymes, including MMP-9

  10. CYP2C19*2 status in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis

    Directory of Open Access Journals (Sweden)

    Laska AJ

    2017-05-01

    Full Text Available Amanda J Laska,1 Marie J Han,1 Josh A Lospinoso,2 Patrick J Brown,1 Thomas M Beachkofsky1 1Department of Dermatology, San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, 2780th Military Intelligence Brigade, Ft Meade, MD, USA Purpose: Genetic polymorphisms have been linked to an increased predisposition to developing certain diseases. For example, patients of Han-Chinese descent carrying the HLA-B*1502 allele are at an increased risk of developing Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN if given carbamazepine. Given the complexity of in vivo drug metabolism, it is plausible that the activity of enzyme systems unrelated to specific drug metabolism may be important. Although multiple biomarkers have been identified in unique ethnic groups, there has yet to be a study investigating the presence of the slow metabolizing allele of CYP2C19, denoted CYP2C19*2, in diverse groups and the risk of developing SJS/TEN. Patients and methods: This study looked into the carrier status of CYP2C19*2, a poor metabolizing variant of CYP2C19, in patients diagnosed with SJS/TEN. We looked at its status in our series as a whole and when patients were divided by ethnicity. Genomic DNA was extracted from formalin-fixed paraffin-embedded tissue of patients with biopsy-proven SJS/TEN and real-time polymerase chain reaction was used to assess for the presence of CYP2C19*2. Results: CYP2C19*2 status was determined in 47 patients. Twenty-nine of these 47 patients had a single medication implicated as causing their disease, and eight of these patients were heterozygous or homozygous for CYP2C19*2. There was insufficient evidence to conclude that the presence of CYP2C19*2 is an independent predictor of risk for developing SJS/TEN in our series as a whole. This analysis also confirmed that the frequency of the CYP2C19*2 polymorphism within the different ethnicities in our series did not vary statistically from reported ethnic

  11. Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women.

    Directory of Open Access Journals (Sweden)

    Lauren Knight

    Full Text Available Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN form a spectrum of a rare and life-threatening cutaneous drug reaction. SJS/TEN in pregnancy poses largely unknown risk factors and outcomes for both the mother and foetus compared to the general population.We conducted a study of consecutive pregnant women admitted to single tertiary referral centre in South Africa with SJS/TEN over a 3 year period. They were all managed by the same medical team using the same protocols. We evaluated their underlying illnesses, offending drugs and the course of pregnancy and outcomes to determine factors influencing maternal and foetal outcomes.We identified twenty-two women who developed SJS/TEN while pregnant, all of them HIV-infected. Their median age was 29 years. The majority 16/22 (73% had SJS, the milder variant of the disease affecting < 10% body surface area. Nevirapine was the offending drug in 21/22 (95% cases. All 22 of the mothers survived with 3/22 (14% developing postpartum sepsis. Pregnancy outcomes were known in 18/22 women and 9/18 (50% babies were delivered by caesarean section. There were 2 foetal deaths at 21 and 31 weeks respectively and both were associated with post-partum sepsis. Postnatal complications occurred in 5 cases, 3 involving the respiratory system and the other two being low birth weight deliveries. Eight placentae and one foetus were sent for histology and none showed macroscopic or microscopic features of SJS/TEN. On follow-up, only 12/20 children were tested for HIV at 6 weeks post-delivery and none of them were HIV-infected. All had received prophylactic ARVs including nevirapine.TEN, the severe form of the disease, was associated with poorer foetal outcomes. SJS/TEN-associated mortality is not increased in HIV-infected pregnant women. Maternal SJS/TEN does not seem to commonly manifest in the foetus.

  12. Purupaljaks / Steven Bertoni

    Index Scriptorium Estoniae

    Bertoni, Steven

    2013-01-01

    Duty Free Shoppersi asutaja Chuck Feeney on oma sihtasutusega Atlantic Philanthropies 30 aasta jooksul annetanud juba üle 6 miljardi dollari toetades erinevaid meditsiini, haridust ning päästeprojekte kogu maailmas, tehes seejuures kõik, et tema isik avalikuks ei tuleks

  13. Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    International Nuclear Information System (INIS)

    Chu, Steven

    2012-01-01

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

  14. Ways of Narrating Memory: Hannah Arendt’s "Eichmann in Jerusalem" and Steven Spielberg’s "Schindler’s List" / Formas de narração da memória: “Eichmann em Israel”, de Hannah Arendt e “A Lista de Schindler”, de Steven Spielberg

    Directory of Open Access Journals (Sweden)

    Wolfgang Heuer

    2012-08-01

    Full Text Available Abstract It is self-evident that events of the past are bound to places and acting people, they are playing a decisive role for memory and history. Meaning and importance of places and actions in the past depend on their contexts and each change inevitably also changes the meaning of the events itself. I would like to demonstrate some of the consequences of such a change by comparing Hannah Arendt’s “Eichmann in Jerusalem“ with Steven Spielberg’s “Schindler’s List“ who decontextualized a factual story and thus changed places and acting people. But before doing this, I would like to emphasize the importance which places and acting people play for memory and history with some perhaps unusual remarks. They refer to the official European history and politics which seem to be marked by the absence of places and acting people.Keywords: Eichmann in Jerusalem, Hannah Arendt, Schindler’s List, Steven SpielbergResumo É autoevidente que acontecimentos do passado estão condicionados a lugares e a pessoas atuantes, que têm papel fundamental na memória e na história. O significado e a importância de lugares e de ações do passado dependem de seu contexto e cada mudança sua inevitavelmente altera também os próprios acontecimentos. Eu gostaria de demonstrar algumas das consequências de tal mudança comparando “Eichmann em Israel”, de Hannah Arendt com “A Lista de Schindler”, de Steven Spielberg, que descontextualizou uma história real e, assim, modificou lugares e pessoas de atuação. Mas antes disso, eu gostaria de enfatizar a importância que lugares e pessoas atuantes têm a memória e na história com alguns comentários talvez inusitados. Eles fazem referência à História oficial e à política da Europa que parecem ser marcados pela ausência de lugares e de pessoas de atuação marcante.Palavras-chaves: Eichmann em Israel, Hannah Arendt, Lista de Schindler, Steven Spielberg

  15. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures.

    Science.gov (United States)

    Schneider, Jeremy A; Cohen, Philip R

    2017-06-01

    Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN. The scientific literature pertaining to SJS and TEN (subsequently referred to as SJS/TEN) is summarized and assessed. In addition, an interventional approach for the clinician is provided. PubMed was searched with the key words: corticosteroids, cyclosporine, etanercept, intravenous immunoglobulin, Stevens-Johnson syndrome, and toxic epidermal necrolysis. The papers generated by the search, and their references, were reviewed. Supportive care is the most universally accepted intervention for SJS/TEN. Specific guidelines differ from the care required for patients with thermal burns. Adjuvant therapies are utilized in most severe cases, but the data are thus far underwhelming and underpowered. Using systemic corticosteroids as sole therapy is not supported. A consensus regarding combined corticosteroids and intravenous immunoglobulin (IVIG) has not been reached. Data regarding IVIG, currently the standard of care for most referral centers, is conflicting. Newer studies regarding cyclosporine and tumor necrosis factor inhibitors are promising, but not powered to provide definitive evidence of efficacy. Data regarding plasmapheresis is equivocal. Thalidomide increases mortality. Clinicians who manage SJS/TEN should seek to employ interventions with the greatest impact on their patients' condition. While supportive care measures may seem an obvious aspect of SJS/TEN patient care, providers should understand that these interventions are imperative and that they differ from the care recommended for other critically ill or burn patients. While adjuvant therapies are frequently discussed and debated for hospitalized patients with SJS/TEN, a standardized management approach is not yet clear based on the current data. Therefore, until further data

  16. Higher-order Zeeman and spin terms in the electron paramagnetic resonance spin Hamiltonian; their description in irreducible form using Cartesian, tesseral spherical tensor and Stevens' operator expressions

    International Nuclear Information System (INIS)

    McGavin, Dennis G; Tennant, W Craighead

    2009-01-01

    In setting up a spin Hamiltonian (SH) to study high-spin Zeeman and high-spin nuclear and/or electronic interactions in electron paramagnetic resonance (EPR) experiments, it is argued that a maximally reduced SH (MRSH) framed in tesseral combinations of spherical tensor operators is necessary. Then, the SH contains only those terms that are necessary and sufficient to describe the particular spin system. The paper proceeds then to obtain interrelationships between the parameters of the MRSH and those of alternative SHs expressed in Cartesian tensor and Stevens operator-equivalent forms. The examples taken, initially, are those of Cartesian and Stevens' expressions for high-spin Zeeman terms of dimension BS 3 and BS 5 . Starting from the well-known decomposition of the general Cartesian tensor of second rank to three irreducible tensors of ranks 0, 1 and 2, the decomposition of Cartesian tensors of ranks 4 and 6 are treated similarly. Next, following a generalization of the tesseral spherical tensor equations, the interrelationships amongst the parameters of the three kinds of expressions, as derived from equivalent SHs, are determined and detailed tables, including all redundancy equations, set out. In each of these cases the lowest symmetry, 1-bar Laue class, is assumed and then examples of relationships for specific higher symmetries derived therefrom. The validity of a spin Hamiltonian containing mixtures of terms from the three expressions is considered in some detail for several specific symmetries, including again the lowest symmetry. Finally, we address the application of some of the relationships derived here to seldom-observed low-symmetry effects in EPR spectra, when high-spin electronic and nuclear interactions are present.

  17. In Conversation with Susan Holtz | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-11-26

    Nov 26, 2010 ... I would say that almost all the practical, on-the-ground progress that is ... on how the integration of different people's perspectives actually happens. ... more and less successful efforts within any one of these approaches.

  18. Susan G. Komen for the Cure

    Science.gov (United States)

    ... de sus senos:Consejos útiles para mujeres El Cancer de Mama y el Medio Ambiente: Preguntas y Respuestas Guía de herramientas de educación sobre el cancer de seno para comunidades hispanas/Latinas About Us ...

  19. Roberts, Dennis C. & Komives, Susan R.

    African Journals Online (AJOL)

    Enhancing Student Learning and Development in Cross-Border Higher ... importance of the integration of students' experience in both the classroom ... practices can be motivated, the diversity in terms of offerings – on institutional and cultural.

  20. Entretien avec Susan Holtz | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    26 nov. 2010 ... À cause des difficultés que pose la convergence des politiques, il semble y avoir un besoin criant d'institutions et de processus nouveaux, voire d'une nouvelle manière d'être culturelle et sociale. À quoi pouvons-nous nous attendre de façon réaliste en ce qui concerne un consensus entre les intervenants, ...

  1. Analysis of Body Constitution of Fifty-two Patients with Stevens-Johnson Syndrome (SJS) Using Kampo Medical Questionnaires: Prediction of SJS based on Body Constitution Using Decision Tree

    OpenAIRE

    大嶋, 繁; 羽鳥, 有紀子; 本間, 精一; 寺澤, 捷年; 齋藤, 侑也; 小林, 大介

    2011-01-01

    Reports have indicated a relationship between adverse drug reaction (ADR) and Human Leukocyte Antigen (HLA) polymorphism and a relationship between Body Constitution (BC) and HLA polymorphism. Thus, a relationship between ADR and BC is suggested. We therefore created a questionnaire (hereinafter “Questionnaire”) to survey the typical BC of Stevens-Johnson Syndrome (SJS) patients to determine how they differ from healthy persons, and studied the relationship between the development of SJS and ...

  2. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working Group.

    Science.gov (United States)

    Maverakis, Emanual; Wang, Elizabeth A; Shinkai, Kanade; Mahasirimongkol, Surakameth; Margolis, David J; Avigan, Mark; Chung, Wen-Hung; Goldman, Jennifer; La Grenade, Lois; Pirmohamed, Munir; Shear, Neil H; Tassaeeyakul, Wichittra; Hoetzenecker, Wolfram; Klaewsongkram, Jettanong; Rerkpattanapipat, Ticha; Manuyakorn, Wiparat; Yasuda, Sally Usdin; Sharon, Victoria R; Sukhov, Andrea; Micheletti, Robert; Struewing, Jeff; French, Lars E; Cheng, Michelle Y

    2017-06-01

    Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are rare, acute, life-threatening dermatologic disorders involving the skin and mucous membranes. Research into these conditions is hampered by a lack of standardization of case reporting and data collection. To establish a standardized case report form to facilitate comparisons and maintain data quality based on an international panel of SJS/TEN experts who performed a Delphi consensus-building exercise. The elements presented for committee scrutiny were adapted from previous case report forms and from PubMed literature searches of highly cited manuscripts pertaining to SJS/TEN. The expert opinions and experience of the members of the consensus group were included in the discussion. Overall, 21 out of 29 experts who were invited to participate in the online Delphi exercise agreed to participate. Surveys at each stage were administered via an online survery software tool. For the first 2 Delphi rounds, results were analyzed using the Interpercentile Range Adjusted for Symmetry method and statements that passed consensus formulated a new case report form. For the third Delphi round, the case report form was presented to the committee, who agreed that it was "appropriate and useful" for documenting cases of SJS/TEN, making it more reliable and valuable for future research endeavors. With the consensus of international experts, a case report form for SJS/TEN has been created to help standardize the collection of patient information in future studies and the documentation of individual cases.

  3. In Silico Risk Assessment of HLA-A*02:06-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Caused by Cold Medicine Ingredients

    Directory of Open Access Journals (Sweden)

    Hideto Isogai

    2013-01-01

    Full Text Available Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN are severe drug hypersensitivities with high mortality. Typical over-the-counter drugs of cold medicines are suggested to be causative. As multiple ingredients are generally contained in cold medicines, it is of particular interest to investigate which ingredients are responsible for SJS/TEN. However, experimental examination of causal relationships between SJS/TEN and a particular drug molecule is not straightforward. Significant association between HLA-A*02:06 and SJS/TEN with severe ocular surface complications has been observed in the Japanese. In the present study, we have undertaken in silico docking simulations between various ingredients contained in cold medicines available in Japan and the HLA-A*02:06 molecule. We use the composite risk index (CRI that is the absolute value of the binding affinity multiplied by the daily dose to assess the potential risk of the adverse reactions. The drugs which have been recognized as causative drugs of SJS/TEN in Japan have revealed relatively high CRI, and the association between SJS/TEN and HLA-A*02:06 has been qualitatively verified. The results have also shown that some drugs whose links to SJS/TEN have not been clinically recognized in Japan show the high CRI and suggested that attention should be paid to their adverse drug reactions.

  4. Fatal Toxic Epidermal Necrolysis Induced by Carbamazepine Treatment in a Patient Who Previously had Carbamazepine-induced Stevens-Johnson Syndrome

    Directory of Open Access Journals (Sweden)

    Li-Yen Huang

    2007-12-01

    Full Text Available Toxic epidermal necrolysis (TEN is a rare but life-threatening skin disease that is most commonly drug-induced. It has recently been suggested that Stevens-Johnson syndrome (SJS belongs to the same group of skin disorders, although it has a lower mortality rate than TEN. We report the case of a 26-year-old male schizophrenic patient with a history of carbamazepine-induced SJS 5 years earlier. At the time of his current admission, he was admitted to our psychiatry department with acute agitation due to schizophrenia. However, the patient and his family denied history of drug allergy. After 3 days of carbamazepine treatment, the patient developed TEN (body surface area > 90%. He was transferred to the burn center, but despite appropriate treatment, including intravenous hydrocortisone 200 mg q6h and being covered with sterile biological material, he died. It is important to note that re-administration of a drug that previously caused SJS may lead to TEN, which has a very high mortality rate.

  5. Síndrome de Stevens-Johnson e Necrólise Epidérmica Tóxica em um hospital do Distrito Federal

    Directory of Open Access Journals (Sweden)

    Mariane Ferreira Barbosa Emerick

    2014-12-01

    Full Text Available Objetivou-se analisar as características demográficas e clínicas dos clientes diagnosticados com Síndrome de Stevens Johnson (SSJ e Necrólise Epidérmica Tóxica (NET, bem como identificar as ações dos profissionais de saúde para o manejo das Reações Adversas a Medicamentos (RAM em um hospital público do Distrito Federal. Pesquisa descritiva, retrospectiva, com abordagem quantitativa. Dados coletados em todos os prontuários de 22 clientes internados de janeiro de 2005 a setembro de 2012. Análise mediante estatística descritiva. Houve aumento gradativo de casos, com maior número nos anos de 2007 e 2012. Dos casos analisados, 9 foram diagnosticados com NET e 7 com SSJ; predominaram as mulheres (14 e a faixa etária de 21 aos 40 anos (10; 21 obtiveram cura. Os fármacos associados a RAM mais frequentes foram os antiepilépticos (10. Observou-se fragilidade nos registros clínicos nos prontuários e nas ações de monitoramento de RAM no serviço estudado.

  6. Response to Dr Stevens' letter ref. Visitisen et al: "Short-term effects of night shift work on breast cancer risk: a cohort study of payroll data"

    DEFF Research Database (Denmark)

    Kolstad, Henrik A; Garde, Anne Helene; Hansen, Åse Marie

    2017-01-01

    We thank Dr Richard Stevens for his comments (1) on our recent article that showed no increased risk of breast cancer following recent night shift work when compared with recent day shift work (2). This finding was based on linkage of day-by-day information on working hours and breast cancer...... incidence data. Results are thus less likely to have been biased by differential misclassification than findings from earlier studies relying on self-report (3). We defined a night shift as ≥3 hours of work between 24:00-05:00 hours and a day shift as ≥3 hours work between 6:00-20:00 hours. This day shift...... definitions of shifts affect the risk of breast cancer, which will be possible using this type of data. We only had information on working hours from 2007 and onwards, and night shift work prior to 2007 could have confounded our analyses towards no effect but only if inversely associated with night shift work...

  7. Response to Dr Stevens' letter ref. Visitisen et al: "Short-term effects of night shift work on breast cancer risk: a cohort study of payroll data".

    Science.gov (United States)

    Kolstad, Henrik A; Garde, Anne Helene; Hansen, Åse Marie; Frydenberg, Morten; Christiansen, Peer; Vistisen, Helene Tilma; Bonde, Jens Peter E

    2017-01-01

    We thank Dr Richard Stevens for his comments (1) on our recent article that showed no increased risk of breast cancer following recent night shift work when compared with recent day shift work (2). This finding was based on linkage of day-by-day information on working hours and breast cancer incidence data. Results are thus less likely to have been biased by differential misclassification than findings from earlier studies relying on self-report (3). We defined a night shift as ≥3 hours of work between 24:00-05:00 hours and a day shift as ≥3 hours work between 6:00-20:00 hours. This day shift definition did not exclude shifts starting before 05:00 or ending after 24:00 hours. However, this affected only 0.02% and 0.3% of all day shifts, respectively. This diminutive misclassification, that is expected to be non-differential, can hardly explain our negative findings. It is suggested that shifts that begin after 07:00 and end before 18:00 would constitute a more sensible baseline comparison group. Since the biological mechanism is not certain, it is not obvious to us if this will be a more appropriate reference than the present. However, we agree that future studies should test how different definitions of shifts affect the risk of breast cancer, which will be possible using this type of data. We only had information on working hours from 2007 and onwards, and night shift work prior to 2007 could have confounded our analyses towards no effect but only if inversely associated with night shift work in 2007 or later. We find this unlikely. Left truncation could also have biased findings towards the null. We therefore supplemented analyses of the total study population with analyses of the one-third of the population with first recorded employment in 2008 or later (the inception population). Even if the mean age was 35.5 years - and many undoubtedly had been working (with and without night shifts) prior to 2008 - this population should be less affected by such

  8. Minor salivary glands and labial mucous membrane graft in the treatment of severe symblepharon and dry eye in patients with Stevens-Johnson syndrome.

    Science.gov (United States)

    Sant' Anna, Ana Estela B P P; Hazarbassanov, Rossen M; de Freitas, Denise; Gomes, José Álvaro P

    2012-02-01

    To evaluate minor salivary glands and labial mucous membrane graft in patients with severe symblepharon and dry eye secondary to Stevens-Johnson syndrome (SJS). A prospective, non-comparative, interventional case series of 19 patients with severe symblepharon and dry eye secondary to SJS who underwent labial mucous membrane and minor salivary glands transplantation. A complete ophthalmic examination including the Schirmer I test was performed prior to and following surgery. All patients had a preoperative Schirmer I test value of zero. Nineteen patients with severe symblepharon and dry eye secondary to SJS were included in the study. There was a statistically significant improvement in the best spectacle-corrected visual acuity in eight patients (t test; p=0.0070). Values obtained in the Schirmer I test improved significantly in 14 eyes (73.7%) 6 months following surgery (χ(2) test; p=0.0094). A statistically significant increase in tear production (Schirmer I test) was found in eyes that received more than 10 glands per graft compared with eyes that received fewer glands (χ(2) test; p=0.0096). Corneal transparency improved significantly in 11 (72.2%) eyes and corneal neovascularisation improved significantly in five eyes (29.4%) (McNemar test; p=0.001 and p=0.0005). The symptoms questionnaire revealed improvement in foreign body sensation in 53.6% of the patients, in photophobia in 50.2% and in pain in 54.8% (Kruskal-Wallis test; p=0.0167). Labial mucous membrane and minor salivary glands transplantation were found to constitute a good option for the treatment of severe symblepharon and dry eye secondary to SJS. This may be considered as a step prior to limbal stem cell and corneal transplantation in these patients.

  9. Stevens-Johnson syndrome and toxic epidermal necrolysis due to anticonvulsants share certain clinical and laboratory features with drug-induced hypersensitivity syndrome, despite differences in cutaneous presentations.

    Science.gov (United States)

    Teraki, Y; Shibuya, M; Izaki, S

    2010-10-01

    Drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (HHV) reactivation. The diagnosis of DIHS is based on the combined presence of these findings. Anticonvulsants are a major cause of DIHS and may also cause Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We examined whether SJS/TEN due to anticonvulsants display similar clinical and laboratory features seen in DIHS. Patients diagnosed with SJS or TEN due to anticonvulsants (n = 8) were examined and their clinical features and laboratory findings were compared with patients with anticonvulsant-related DIHS (n = 6). Seven of the eight patients with SJS/TEN developed symptoms > 3 weeks after starting anticonvulsants. Hepatic dysfunction was present in six patients with SJS/TEN and five patients with DIHS. Leucocytosis and/or eosinophilia was noted in seven patients with SJS/TEN and four patients with DIHS. Only one patient in the SJS/TEN group had atypical lymphocytosis; this was present in four patients with DIHS. Reactivation of HHV-6 was detected in one of the four patients tested in the SJS/TEN group, although it was seen in five of the six patients with DIHS. TSJS/TEN due to anticonvulsants may exhibit some clinical and laboratory features of DIHS. The nature of the cutaneous involvement should be emphasized in the diagnosis of DIHS. © 2009 The Author(s). Journal compilation © 2009 British Association of Dermatologists.

  10. Racial disparities in the risk of Stevens-Johnson Syndrome and toxic epidermal necrolysis as urate-lowering drug adverse events in the United States.

    Science.gov (United States)

    Lu, Na; Rai, Sharan K; Terkeltaub, Robert; Kim, Seoyoung C; Menendez, Mariano E; Choi, Hyon K

    2016-10-01

    HLA-B*5801 allele carriage (a strong determinant of allopurinol hypersensitivity syndrome) varies substantially among races, which may lead to racial disparities in the risk of Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) in the context of urate-lowering drug adverse events (ULDAEs). We examined this hypothesis in a large, racially diverse, and generalizable setting. Using a database representative of US hospitalizations (2009-2013), we investigated the racial distribution of hospitalized SJS/TEN (principal discharge diagnosis) as ULDAEs (ICD-9-CM Classification of External Causes). Our reference groups included the US Census population, US allopurinol users, and ULDAE hospitalizations without SJS/TEN. We identified 606 cases hospitalized for SJS/TEN as ULDAEs (mean age = 68 years; 44% male), among which there was an overrepresentation of Asians (27%) and Blacks (26%), and an underrepresentation of Whites (29%) and Hispanics (% too-low-to-report), compared with the US Census population (5%, 12%, 67%, and 15%, respectively). The hospitalization rate ratios for SJS/TEN among Asians, Blacks, and Whites were 11.9, 5.0, and 1.0 (referent), respectively. These associations persisted using other national referents. According to the NHANES 2009-2012, allopurinol constituted 96.8% of urate-lowering drug use, followed by probenecid (2.1%). These national data indicate that Asians and Blacks have a substantially higher risk of SJS/TEN as ULDAEs than Whites (or Hispanics), correlating well with corresponding frequencies of HLA-B*5801 in the US population (i.e., 7.4%, 4%, 1%, and 1%, respectively). Given its market dominance and established association with SJS/TEN, our findings support the use of vigilance in these minorities when considering allopurinol. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital

    Directory of Open Access Journals (Sweden)

    Susheera Chatproedprai

    2018-01-01

    Full Text Available Aim. To determine the probable causative factors, clinical features, and treatment outcomes of Stevens-Johnson syndrome (SJS, toxic epidermal necrolysis (TEN, and SJS-TEN overlap in children. Methods. A 20-year database review of all children diagnosed with SJS/TEN/SJS-TEN overlap at the King Chulalongkorn Memorial Hospital, Thailand. Results. 36 patients (M : F, 16 : 20 with the mean age of 9.2±4.0 years were identified. There were 20 cases of SJS, 4 cases of SJS-TEN overlap, and 12 cases of TEN. Drugs were the leading cause for the diseases (72.3%; antiepileptics were the most common culprits (36.1%. Cutaneous morphology at presentation was morbilliform rash (83.3%, blister (38.9%, targetoid lesions (25.0%, and purpuric macules (2.8%. Oral mucosa (97.2% and eye (83.3% were the 2 most common mucosal involvements. Majority of the cases (77.8% were treated with systemic corticosteroids, intravenous immunoglobulin, or both. Treatment outcomes between those who received systemic therapy and those who received only supportive care were comparable. Skin and eye were the principal sites of short-term and long-term complications. Conclusions. SJS/TEN are not common but are serious diseases which lead to significant morbidities in children. Early withdrawal of suspicious causes and meticulous supportive care are very important. This study found that the systemic therapy was not superior to supportive care because the treatment outcomes for both groups were comparable.

  12. Genotipificación de HLA-B en pacientes colombianos afectados por el síndrome Stevens-Johnson y la Necrólisis Epidérmica Tóxica

    OpenAIRE

    León Ruiz, Maria Juliana

    2014-01-01

    Las reacciones alérgicas a medicamentos cutáneas severas (RAM) como el Síndrome Stevens Johnson (SJS) y la Necrólisis Epidérmica Tóxica (NET),caracterizadas por exantema, erosión de la piel y las membranas mucosas, flictenas, desprendimiento de la piel secundario a la muerte de queratinocitos y compromiso ocular. Son infrecuentes en la población pero con elevada morbi-mortalidad, se presentan luego de la administración de diferentes fármacos. En Asia se ha asociado el alelo HLA-B*15:02 como m...

  13. Stability of epitheliotrophic factors in autologous serum eye drops from chronic Stevens-Johnson syndrome dry eye compared to non-autoimmune dry eye.

    Science.gov (United States)

    Phasukkijwatana, Nopasak; Lertrit, Patcharee; Liammongkolkul, Sompong; Prabhasawat, Pinnita

    2011-09-01

    To compare the concentrations of epitheliotrophic factors in autologous serum eye drops (ASE) prepared from sera of chronic Stevens-Johnson syndrome (SJS) patients with dry eyes to those prepared from non-autoimmune dry eye controls and to study the stability of the epitheliotrophic factors in different storage conditions. Twenty-percent ASE were prepared from 10 chronic SJS patients with dry eyes and 10 age-matched non-autoimmune dry eye controls. The concentrations of major epitheliotrophic factors comprising epidermal growth factor (EGF), transforming growth factor-beta1 (TGF-β1), transforming growth factor-beta2 (TGF-β2), and fibronectin in those ASE preparations were determined by enzyme-linked immunosorbent assay (ELISA) at baseline and after different storage conditions: at 4 °C for 1 week and 1 month; and at -20 °C for 1, 3 and 6 months. There were no significant differences in the concentrations of EGF, TGF-β1, TGF-β2 and fibronectin in 20% ASE between the SJS and control groups (EGF: 176.9 ± 40.9 vs. 185.5 ± 36.9 pg/mL, TGF-β1: 9.5 ± 2.1 vs. 9.5 ± 1.9 ng/mL, TGF-β2: 55.3 ± 30.0 vs. 63.91 ± 45.6 pg/mL and fibronectin: 70.5 ± 20.2 vs. 62.2 ± 21.3 µg/mL, respectively). These factors were stable at 4 °C for up to 1 month. Storage at -20 °C for up to 6 months resulted in a slight decrease in TGF-β1 (SJS: from 9.5-8.4 ng/mL, p dry eye patients, and that ASE should be sufficiently stable for up to 6 months, if stored properly at -20 °C.

  14. An Interview with Steven Millhauser

    Directory of Open Access Journals (Sweden)

    Étienne Février

    2012-01-01

    Full Text Available Etienne Février : I would like to begin this interview with a question about architecture. Images of architecture appear frequently in your fiction, from Martin Dressler to more recent collections like Dangerous Laughter. In that collection’s “thirteen stories,” we find a tower reaching all the way to heaven, a life-size replica of a town so precise that even the “levels of salt in the saltshakers” match those of the original town, and a series of outwardly expanding domes—covering a house, f...

  15. Hydrogeologic framework, groundwater and surface-water systems, land use, pumpage, and water budget of the Chamokane Creek basin, Stevens County, Washington

    Science.gov (United States)

    Kahle, Sue C.; Taylor, William A.; Lin, Sonja; Sumioka, Steven S.; Olsen, Theresa D.

    2010-01-01

    A study of the water resources of the unconsolidated groundwater system of the Chamokane Creek basin was conducted to determine the hydrogeologic framework, interactions of shallow and deep parts of the groundwater system with each other and the surface-water system, changes in land use and land cover, and water-use estimates. Chamokane Creek basin is a 179 mi2 area that borders and partially overlaps the Spokane Indian Reservation in southern Stevens County in northeastern Washington State. Aquifers within the Chamokane Creek basin are part of a sequence of glaciofluvial and glaciolacustrine sediment that may reach total thicknesses of about 600 ft. In 1979, most of the water rights in the Chamokane Creek basin were adjudicated by the United States District Court requiring regulation in favor of the Spokane Tribe of Indians' senior water right. The Spokane Tribe, the State of Washington, and the United States are concerned about the effects of additional groundwater development within the basin on Chamokane Creek. Information provided by this study will be used to evaluate the effects of potential increases in groundwater withdrawals on groundwater and surface-water resources within the basin. The hydrogeologic framework consists of six hydrogeologic units: The Upper outwash aquifer, the Landslide Unit, the Valley Confining Unit, the Lower Aquifer, the Basalt Unit, and the Bedrock Unit. The Upper outwash aquifer occurs along the valley floors of the study area and consists of sand, gravel, cobbles, boulders, with minor silt and (or) clay interbeds in places. The Lower aquifer is a confined aquifer consisting of sand and gravel that occurs at depth below the Valley confining unit. Median horizontal hydraulic conductivity values for the Upper outwash aquifer, Valley confining unit, Lower aquifer, and Basalt unit were estimated to be 540, 10, 19, and 3.7 ft/d, respectively. Many low-flow stream discharge measurements at sites on Chamokane Creek and its tributaries

  16. L’art du vitrail en France au temps de la reconstruction et de la croissance. Note sur les fonds Hébert-Stevens - Bony conservés aux Archives nationales du monde du travail (Fonds n° 2002 001

    Directory of Open Access Journals (Sweden)

    Christian Hottin

    2009-11-01

    Full Text Available Cet article a pour objet de présenter brièvement le fonds de l’atelier Hébert-Stevens - Bony, entré aux Archives nationales (Archives nationales du monde du travail, Roubaix en 2002

  17. Efficacy of Hummel (Modified Schlumberger Arrays of Vertical Electrical Sounding in Groundwater Exploration: Case Study of Parts of Ibadan Metropolis, Southwestern Nigeria

    Directory of Open Access Journals (Sweden)

    Micheal Oladunjoye

    2015-01-01

    Full Text Available This research compared the interpretation results of the Vertical Electrical Sounding data acquired using the conventional Schlumberger and modified Schlumberger arrays with a view to assessing the effectiveness of the modified Schlumberger arrays of vertical electrical sounding as an alternative to the conventional Schlumberger array at sites with space constraint during groundwater exploration. A total of thirty-seven (37 sounding locations were occupied and one hundred (100 sounding data for both conventional Schlumberger and modified Schlumberger arrays were collected across different rock units within Ibadan metropolis, south-western Nigeria, with electrode spacing (AB/2 ranging from 1 to 75 m. The field data were interpreted qualitatively by curve matching and computer iterative methods. Also, statistical analysis of subsurface units and the coefficient of correlation “R” of the statistical plots of the field data shows the relationship between the different arrays. The raw data plot of the different arrays shows significant similarities while statistical analysis of the geo-electric parameters obtained from the different arrays across varied lithologic units show that strong relationships exist between the different field methods. The coefficient of correlation R with values ranging from 0.7 to 0.99 implies that a good similarity exists between the different field methods employed in this study. Hence, modified Schlumberger arrays can be said to be a good alternative to the conventional Schlumberger array for groundwater exploration especially in urban settings where space constraint is a major challenge.

  18. Contravene, write ... About the pain of others of Susan Sontag

    Directory of Open Access Journals (Sweden)

    Lucía Belén Couso

    2014-08-01

    Full Text Available Regarding the pain of others challenges our knowledge, challenges what is held as true. We appreciate this attitude condensed in the verb “to defy”. We analyze how Sontag develops her hypothesis and, from that point onward, which is the idea of criticism that emerges from the writing of Regarding the pain of others. Our analysis focuses on three of its topics: the reviewing of the ideas about the war that Virginia Woolf establishes on Three Guineas, the discussion of her own text On photography, and the criticism about Sebastião Salgado’s photography.

  19. A polarised SUSANS facility to study magnetic systems

    Indian Academy of Sciences (India)

    The experiment was carried out at the V12b double crystal diffractometer set ... upper pole piece and just below the lower pole piece, within a magnet-grade soft iron 'C'. ... about 3 µm with the up- and 9 µm with the down-spin neutrons.

  20. From Estonian Exile to Executive Office / Susan Frith

    Index Scriptorium Estoniae

    Frith, Susan

    2008-01-01

    Eesti Vabariigi Presidendi Toomas Hendrik Ilvese elukäigust, haridusteest, poliitilistest vaadetest. T. H. Ilves lõpetas Pennsylvania ülikooli psühholoogia alal magistrikraadiga 1978. a. Artiklis on kasutatud telefoniintervjuud presidendiga. T. H. Ilvese kohta avaldavad arvamust ülikoolikaaslane Brian Wandell ja Eesti Rahvuskomitee Ühendriikides endine president Juhan Simonson. Ülevaade artiklist ilmunud ka: Vaba Eesti Sõna, 24. jaan. 2008, lk. 7, 10: Vaga, Airi. Eesti president Toomas H. Ilves Pennsylvania ülikooli ajakirjas

  1. Rene Valner ja Mikk Suursild - lihtsa elu tegelased / Susan Lahesalu

    Index Scriptorium Estoniae

    Lahesalu, Susan

    2007-01-01

    Arhitekt Rene Valner ja Mikk Suursild - tandem nimega UNITe - ehitavad ökonoomseid ja ökoloogilisi looduslikest materjalidest maju. Nende koostöös on valminud ka Peipsi ääres Nina külas 3 põhumaja. Ott Kadariku, Margit Mutso ja Kuido Kartau kommentaarid

  2. Entretien avec Susan Holtz | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    26 nov. 2010 ... ... Centre de recherches pour le développement international comme l'un des ... Toutefois, le discours public sur l'intégration d'objectifs environnementaux et .... très conservatrice des experts du droit commercial international, ...

  3. Interview with Pennsylvania PUC chairman Susan M. Shanaman

    International Nuclear Information System (INIS)

    Utroska, D.

    1981-01-01

    Chairman Shanaman notes that Pennsylvania law justifies the Public Utility Commission (PUC) refusal to charge ratepayers for the cost of Three Mile Island units 1 and 2, neither of which are providing service, because ratepayers are already paying the costs of replacement power. The PUC chairman points to other service territories around the country where rates are kept below national averages because the average income level is low. The Metropolitan Edison Company is seeking Federal relief as well as legislative permission to put TMI-1 back into the rate base in fairness to ratepayers, but the PUC does not see bankruptcy for the utility as an appropriate way to force Federal assistance. The Administration needs to understand the local impact of Federal policies, especially those which are incompatible with state situations. Appropriate involvement includes nuclear waste research and underwriting some of the cleanup costs of onsite accidents that are too large for a single utility to handle. Chairman Shanaman feels that ratepayers should contribute to the insurance premium for future accidents, but not retroactively to support TMI-2. Nuclear power plant construction in the US will not progress until the issues of TMI-2 are resolved

  4. Case Report: Stevens-Johnson syndrome following a single double dosing of nevirapine-containing regimen once in an HIV-infected woman on long-term antiretroviral therapy. [version 1; referees: 1 approved, 2 approved with reservations

    Directory of Open Access Journals (Sweden)

    Betty Kakande

    2015-06-01

    Full Text Available A 31-year old HIV-infected African woman on nevirapine, tenofovir and lamivudine for more than 4 years presented with an 8-day history of symptoms and signs of Stevens-Johnson syndrome. She was on no other medication. Her viral load was undetectable and she had maintained a CD4 count of between 356 and 387cells/mm3 in the preceding 2½ years. She missed her antiretrovirals 10 days before the onset of her symptoms and subsequently doubled her daily dose the following day. She had been on no other medication in the preceding 8 weeks. Her ARVs were stopped and she fully re-epithelialized with the exception of the lips, over the following 10 days. She was started on a daily single tablet of Odimune® (a fixed drug combination antiretroviral containing tenofovir, emtricitabine and efavirenz.   Nevirapine is the most common offender in cases of antiretroviral-associated SJS in published literature. Lamivudine is very rarely implicated while there are no similar reports with tenofovir.  We concluded that nevirapine was by far the most likely offender in this case. Nevirapine toxicity is associated with high CD4 counts, undetectable viral load and high drug plasma level. We postulate that the sudden increase of the plasma levels of nevirapine in a patient with a high CD4 count and undetectable viral load created a perfect storm for the development of SJS in our patient, who had been on the NVP-containing regimen for many years. Clinicians should be aware that severe adverse drug reactions are dynamic and can occur even when the drug has been in use for a long time.

  5. Case Report: Stevens-Johnson syndrome following a single double dosing of nevirapine-containing regimen once in an HIV-infected woman on long-term antiretroviral therapy.

    Science.gov (United States)

    Kakande, Betty; Isaacs, Thuraya; Muloiwa, Rudzani; Dlamini, Sipho; Lehloenya, Rannakoe

    2015-01-01

    A 31-year old HIV-infected African woman on nevirapine, tenofovir and lamivudine for more than 4 years presented with an 8-day history of symptoms and signs of Stevens-Johnson syndrome. She was on no other medication. Her viral load was undetectable and she had maintained a CD4 count of between 356 and 387cells/mm (3) in the preceding 2½ years. She missed her antiretrovirals 10 days before the onset of her symptoms and subsequently doubled her daily dose the following day. She had been on no other medication in the preceding 8 weeks. Her ARVs were stopped and she fully re-epithelialized with the exception of the lips, over the following 10 days. She was started on a daily single tablet of Odimune® (a fixed drug combination antiretroviral containing tenofovir, emtricitabine and efavirenz). Nevirapine is the most common offender in cases of antiretroviral-associated SJS in published literature. Lamivudine is very rarely implicated while there are no similar reports with tenofovir.  We concluded that nevirapine was by far the most likely offender in this case. Nevirapine toxicity is associated with high CD4 counts, undetectable viral load and high drug plasma level. We postulate that the sudden increase of the plasma levels of nevirapine in a patient with a high CD4 count and undetectable viral load created a perfect storm for the development of SJS in our patient, who had been on the NVP-containing regimen for many years. Clinicians should be aware that severe adverse drug reactions are dynamic and can occur even when the drug has been in use for a long time.

  6. Cost-effectiveness analysis of HLA-B*58: 01 genetic testing before initiation of allopurinol therapy to prevent allopurinol-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in a Malaysian population.

    Science.gov (United States)

    Chong, Huey Yi; Lim, Yi Heng; Prawjaeng, Juthamas; Tassaneeyakul, Wichittra; Mohamed, Zahurin; Chaiyakunapruk, Nathorn

    2018-02-01

    Studies found a strong association between allopurinol-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and the HLA-B*58:01 allele. HLA-B*58:01 screening-guided therapy may mitigate the risk of allopurinol-induced SJS/TEN. This study aimed to evaluate the cost-effectiveness of HLA-B*58:01 screening before allopurinol therapy initiation compared with the current practice of no screening for Malaysian patients with chronic gout in whom a hypouricemic agent is indicated. This cost-effectiveness analysis adopted a societal perspective with a lifetime horizon. A decision tree model coupled with Markov models were developed to estimate the costs and outcomes, represented by quality-adjusted life years (QALYs) gained, of three treatment strategies: (a) current practice (allopurinol initiation without HLA-B*58:01 screening); (b) HLA-B*58:01 screening before allopurinol initiation; and (c) alternative treatment (probenecid) without HLA-B*58:01 screening. The model was populated with data from literature review, meta-analysis, and published government documents. Cost values were adjusted for the year 2016, with costs and health outcomes discounted at 3% per annum. A series of sensitivity analysis including probabilistic sensitivity analysis were carried out to determine the robustness of the findings. Both HLA-B*58:01 screening and probenecid prescribing were dominated by current practice. Compared with current practice, HLA-B*58:01 screening resulted in 0.252 QALYs loss per patient at an additional cost of USD 322, whereas probenecid prescribing resulted in 1.928 QALYs loss per patient at an additional cost of USD 2203. One SJS/TEN case would be avoided for every 556 patients screened. At the cost-effectiveness threshold of USD 8695 per QALY, the probability of current practice being the best choice is 99.9%, in contrast with 0.1 and 0% in HLA-B*58:01 screening and probenecid prescribing, respectively. This is because of the low incidence of

  7. 75 FR 57974 - Senior Executive Service Performance Review Board

    Science.gov (United States)

    2010-09-23

    .... Crocetti Jr., Louis D. Cullen, Susan M. Cummiskey, Chris Daitch, William Davis, Delia P. Dayton, Mark de.... Armstrong, Charles R. Ayala, Janice Aytes, Michael L. Bacon, Roxana Baldwin, William D. Baroukh, Nader Barr... Brundage, William Bucella, Donna A. Bucher, Steven P. Buckingham, Patricia A. Burke, Richard Butcher...

  8. Modernismi tõlgendamine jätkub / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2007-01-01

    Rahvusvaheline kunstiajalookonverents "Erinevad modernismid, erinevad avangardid. Kesk- ja Ida-Euroopa kunstiprobleemid pärast Teist maailmasõda" Kumu Kunstimuuseumis 27. ja 28. IX. Esinejad: Irena Buzhinska, David Crowley, Branislav Dmitrijevic, Sirje Helme, Henry Meyric Hughes, Jaak Kangilaski, Liljana Kolesnik, Andres Kurg, Vojtech Lahoda, Steven Mansbach, Pjotr Piotrowski, Stefanie Reetz, Susan E. Reid, Skaidra Trilupaite, Borut Vogelnik

  9. Too Many Choices?

    Science.gov (United States)

    Gardner, Howard

    2002-01-01

    Reviews two books, "The Other Boston Busing Story: What's Won and Lost across the Boundary Line" (Susan E. Eaton) and "Kingdom of Children: Culture and Controversy in the Homeschooling Movement" (Mitchell L. Stevens), which provide revealing perspectives on the experiences of those American families who veture beyond the traditional local school.…

  10. Kamikaze Paksas appoints Borisov / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Leedu presidendi Rolandas Paksase ümber vallandunud skandaali üks võtmeisikuid, Vene kodanik Juri Borissov teatas, et hakkab tööle presidendi ühiskondliku nõunikuna, mõni tund hiljem otsustas president distantseeruda oma valimiskampaania suursponsorist

  11. Paksas declares candidacy amid uncertainty / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Leedu ametieetika peakomisjon otsustas, et ametist tagandatud ekspresident Rolandas Paksas ei saa kolm aastat riigiametites töötada. See otsus võib takistada Paksase kandideerimist ennetähtaegsetel presidendivalimistel. Vt. samas: And here's the competition...

  12. Steven's orbital reduction factor in ionic clusters

    Science.gov (United States)

    Gajek, Z.; Mulak, J.

    1985-11-01

    General expressions for reduction coefficients of matrix elements of angular momentum operator in ionic clusters or molecular systems have been derived. The reduction in this approach results from overlap and covalency effects and plays an important role in the reconciling of magnetic and spectroscopic experimental data. The formulated expressions make possible a phenomenological description of the effect with two independent parameters for typical equidistant clusters. Some detailed calculations also suggest the possibility of a one-parameter description. The results of these calculations for some ionic uranium compounds are presented as an example.

  13. Mayoral controversy resurrects political hostility / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Vilniuse linnapea Arturas Zuokas kuulati üle seoses võimaliku häälteostmisega kohalike omavalitsuste valimistel. A. Zuokas peab ülekuulamise põhjuseks president Rolandas Paksase survet uurimisorganitele

  14. Government promises billions for highways / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Läti transpordiministeerium avaldas riigi teedevõrgu arengukava järgmiseks 25 aastaks, mille kohaselt investeeritakse maanteede ja raudteede ehitusse kuni 18 miljardit litti. Leedu transpordiettevõtjate hinnangul ei ole uued suuremahulised projektid majandusarengu seisukohalt vajalikud

  15. Dr. Steven Chu, Secretary of Energy

    Science.gov (United States)

    addiction to foreign oil, address the global climate crisis and create millions of new jobs. Prior to his , the Korean Academy of Sciences and Technology and numerous other civic and professional organizations

  16. Kindlustushüvitise suuruse määramine kahjukindlustuses läbi kindlustussumma ja kindlustusväärtuse : [bakalaureusetöö] / Hannele Hummel ; Tartu Ülikool, õigusteaduskond ; juhendaja: Age Värv

    Index Scriptorium Estoniae

    Hummel, Hannele

    2010-01-01

    Kahju hüvitamise üldpõhimõtetest kahjukindlustuses, kindlustussumma ja kindlustusväärtuse määramisest kahjukindlustuslepingu sõlmimisel, hüvitise suuruse piiritlemisest kindlustusjuhtumi toimumise korral

  17. 77 FR 73663 - Susan F. Knott; Denial of Hearing; Final Debarment Order

    Science.gov (United States)

    2012-12-11

    ... determination urged (see 21 CFR 12.24(b)). The Chief Scientist has considered Knott's arguments and concludes... be substituted for an approved drug without the knowledge of the patient. As a result, Knott is... thus there was no demonstration or admission of criminal intent or knowledge underlying her conviction...

  18. Nõukogude "kaasaegne stiil" : sotsialistlik modernism = The Soviet "contemporary style" : a socialist modernism / Susan E. Reid

    Index Scriptorium Estoniae

    Reid, Susan E., 1959-

    2009-01-01

    Modernismile lähenemisest nõukogude kunstis. Nõukogude kunstikriitikast ja -praktikast. Kaasaegne stiil sünteesis arhitektuuriga. Nõukogude Palee teostamata projektist Moskvas. 1962. aastal valminud Moskva Pioneeride Paleest kui stalinistliku praktika hülgamise näitest

  19. In Appreciation of Claude Warren and Susan Rose's "William Pengelly's Techniques of Archaeological Excavation"

    Directory of Open Access Journals (Sweden)

    David L. Browman

    1997-11-01

    Full Text Available The short (40 pages pamphlet by Warren and Rose (1994 provides the answer to a complex question regarding credit for an important archaeological methodology, stratigraphic excavation. Let me set the stage for this appreciation. Continuing research on the beginnings of stratigraphic excavations in North America (Browman and Givens 1996, I sought the origins of the idea of actually excavating by strata, rather than post-facto interpretation, seen in North American as early as 1895 in the work of Henry Chapman Mercer, but not really introduced into the repertoire of American techniques until the work of Gamio, Kidder and Nelson between 1911 and 1914. The roots of the latter three seemed to lie with individuals such as Reisner, Boas, Uhle, who in turn seemed to rely on Hugo Obennaier, Gabriel de Mortillet, Marcellin Boule, and perhaps Pitt-Rivers, while Mercer's work could be traced to Boule and Albert Gaudry. Doggedly following back the roots, I found that Chapman (1989 could make a reasonable case that Pitt-Rivers had actually learned of the idea of strati­graphic excavation from Evans, Prestwich, and Lubbock, from the British scientists working with the Upper and Middle Paleolithic excavations during 1858-1868.

  20. Diasporic Reconciliations of Politics, Love and Trauma: Susan Abulhawa's Quest for Identity in "Mornings in Jenin"

    Science.gov (United States)

    Abu-Shomar, Ayman M.

    2015-01-01

    Negotiating human conditions is an emblematic critical impetus of diaspora informed by multiple cultural possibilities practiced through the creation of multiple spaces that cross the realm of the "self" to that of the "other." It offers a locale to cross from the oppressed "self" to an understanding of an oppressor…

  1. Stevens –Johnson syndrome due to nevirapine | Namayanja ...

    African Journals Online (AJOL)

    African Health Sciences. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 5, No 4 (2005) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here ...

  2. Mazeikiu refinery to stay in Yukos' control / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Vene peaprokuratuur andis välja rahvusvahelise vahistamisorderi Mazheikiu Nafta juhatuse esimehe ja Jukose aktsionäri Mihhail Brudno suhtes. Leedu valitsus kaalub võimalikke samme, sealhulgas Mazheikiu Nafta aktsiate tagasiostmist

  3. The Stevens Integrated Maritime Surveillance Forecast System: Expansion and Enhancement

    National Research Council Canada - National Science Library

    Bruno, Michael S; Blumberg, Alan F

    2006-01-01

    .... In the long-term, the observation and modeling systems will be linked in a unique fashion, whereby the model forecast system will be enhanced by data assimilation, and the observing system will...

  4. Commission : Paksas violated oath of office / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2003-01-01

    Leedu presidendi ümber puhkenud skandaali uuriv Seimi erikomisjon leidis, et president Rolandas Paksas oli ja on oma sidemete tõttu haavatav ning see kujutab ohtu riigi julgeolekule. Lisa: Commission conclusions

  5. Utility privatizations raise as many questions as cash / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2003-01-01

    Leedu valitsus seiskab tõenäoliselt elektrijaotusvõrgu Rytu Skirstomieji Tinklai (RTS) erastamise. Teise võrgufirma Vakaru Skirstomieji Tinklai (VST) erastamiskomisjon on palunud konkursil osalejatelt täpsustatud pakkumisi

  6. Steven Hawking to visit Texas A&M in spring

    CERN Multimedia

    Xavier, D

    2002-01-01

    Stephen Hawking will visit Texas A&M University from Feb. 24 to March 21 2003 to participate in the inaugural meeting of the George P. and Cynthia W. Mitchell Institute for Fundamental Physics. This institute will bring several of the world's top physicists to A&M for a month-long exploration of the latest ideas on topics ranging from superstrings to M-theory and supergravity (1/2 page).

  7. Steven Vogel and His Theory of Comparative Biomechanics

    Indian Academy of Sciences (India)

    IAS Admin

    on the development, physiology, and disease of living things. I have a ... Vogel was a prolific writer of popular science articles and books. .... is a new line of thinking here. Even though the .... to make it suitable to teach engineering stu- dents?

  8. Vilnius mayor dragged into corruption scandal / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Vilniuse linnapea Arturas Zuokase suhtes on algatatud kriminaalmenetlus, süüdistuseks koos korporatsiooni Rubicon juhi Andrius Janukonisega altkäemaksu pakkumine linnavolikogu liikmele Vilmantas Dremale linnapea valimiste eel

  9. MEP : Political parties funded by bribes / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Leedu Sotsiaaldemokraatliku Partei liikme, Euroopa Parlamendi saadiku Aloyzas Sakalase hinnangul finantseeritakse Leedu parteisid altkäemaksudest ja korruptsioonis süüdistatavad parlamendiliikmed tegutsesid oma parteide nimel

  10. Ugly details of MP corruption come to light / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Leedu Seimi korruptsioonivastase võitluse komisjon otsustas avalikustada parlamendiliikmete Vytenis Andriukaitise, Vytautas Kvietkauskase ja Arvydas Vidziunase telefonikõnede lindistused, mis tõendavad, et nad võtsid altkäemaksu kontserni Rubicon Group juhilt Andrius Janukoniselt

  11. 75 FR 9531 - Magnuson-Stevens Act Provisions; Correction

    Science.gov (United States)

    2010-03-03

    ... for comment are not required pursuant to 5 U.S.C. 553, or any other law, the analytical requirements..., rod and reel, spear, trap, slurp gun, hand harvest. C. Charter fishery C. Bandit gear, buoy gear..., gillnet, hand harvest, seine, slurp gun, trap, spear, rod and reel, hook and line. 12. Recreational...

  12. Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis ...

    African Journals Online (AJOL)

    illness until research found that morbidity can result from a ... for the widespread keratinocyte necrosis in SJS and TEN.⁷. Granulysin is the most ... Clinical presentation. SJS and ... Burns Intensive Care Unit may be one of the most important.

  13. Report: Paksas scandal raises privacy concerns / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Inimõiguste ekspertide uuring näitab, et nii Leedu presidendi Rolandas Paksase administratsiooni töötajad, presidendi tegevuse uurijad kui ka Leedu ajakirjandus rikkusid mitmeid inimõigusi, eelkõige aga õigust privaatsusele

  14. Zuokas accuses paper of journalistic blackmail / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Vilniuse linnapea, Leedu Liberaaltsentristliku Liidu liider Arturas Zuokas süüdistab ajalehe Respublika peatoimetajat Vitas Tomkust väljapressimises. Ajaleht on avaldanud mitu Zuokase jaoks ebameeldivat artiklit, milles räägitakse tema väidetavatest sidemetest vastuolulise mainega ettevõtjatega

  15. Analysts : no need to panic over prices / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Pärast EL-iga liitumist on Balti riikides hinnad tõusnud keskmiselt 5,7%, pankade hinnangul on oodata ka inflatsiooni kiirenemist. Lisa: Thank you, accession: Consumer Price Index, percent increase, year-on-year

  16. The Stevens Integrated Maritime Surveillance Forecast System: Expansion and Enhancement

    National Research Council Canada - National Science Library

    Bruno, Michael S; Blumberg, Alan F

    2006-01-01

    ... for the real-time assessment of ocean, weather, environmental, and vessel traffic conditions throughout the New York Harbor region, and the forecast of conditions in the near and long-term and under specific threat scenarios...

  17. 04 Stevens & Terblanché - Sustainable agriculture develop…

    African Journals Online (AJOL)

    annaline

    group development and social capital formation. .... This model of group development is therefore a successive-stage theory as it ... learning or development. .... Bandura (1986) stated that group efficacy “ will influence what people will do as a.

  18. Declan FAHY (2015), The New Celebrity Scientists. Out of the Lab and into the Limelight

    OpenAIRE

    Fines-Neuschild, Mirjam

    2016-01-01

    The New Celebrity Scientists est le premier ouvrage de Declan Fahy. Il y fait le portrait de huit scientifiques en suivant leur parcours jusqu’à la célébrité et présente l’influence de leurs propos sur les politiques publiques. De ces huit scientifiques, trois sont physiciens : Stephen Hawking, Brian Greene et Neil de Grasse Tyson. Sont aussi présentés Richard Dawkins, biologiste, Steven Pinker, psychologue cognitiviste, Stephen Jay Gould, paléontologue, Susan Greenfield, pharmacologue, et Ja...

  19. Uncovering Our History, Teaching Primary Sources (Tarihimizi Keşfetme, Birincil Kaynaklarla Öğretim - Susan H. Veccia

    Directory of Open Access Journals (Sweden)

    Duygu Alphan Şentuna

    2014-05-01

    Full Text Available Okul yıllarından bahseden insanların büyük bir çoğunluğu için tarih dersi, not almak için isimlerin ve tarihlerin ezberlendiği, sınavdan sonra ise unutulduğu bir ders olarak hatıralarda yer alır. Günümüzde tarih öğretiminde önemli gelişmeler olmasına rağmen hala derslerde öğretmenlerin isim, tarih ve ders kitabı merkezli bir öğretim izledikleri görülmektedir. Öğrencilerin eleştirel ve tarihsel düşünme becerisi elde etmeleri için ilk önce bilgiye sahip olmaları gerektiği inancı, öğretmenlerin derslerde yenilikçi yöntemlere yeterli zaman ayırmalarını engellemektedir. Bu durum öğrencilerin tarih dersinden soğumalarına ve dersi zaman kaybı olarak görmelerine neden olmaktadır.

  20. Separated by Sex: A Critical Look at Single-Sex Education for Girls (edited by Susan Morse)

    Science.gov (United States)

    Ceraulo, Reviewed By Sandra C.

    1999-05-01

    As Cornelius Riordan states in his round-table paper, "The challenge of effective and equitable schooling in the next century is to overcome the resistance and recalcitrance of youth cultures in and out of school" (p 58). While this is admittedly not a new problem, it is more complex in its modern form and innovative ways to solve it are needed. In an old tradition, one such attempt has been single-sex schools, which have had particular success with the disadvantaged and white females in American society, with the notable involvement of Catholic religious communities. The report does not make clear whether their successes can be reproduced in some modification of the public school format. However, the AAUW report on single-sex schools sheds light on some of the characteristics that make true learning communities out of ordinary schools and on what it takes to reach disadvantaged girls. For these reasons, the AAUW report is good reading for educators at all levels.

  1. Susan Groag Bell, The Lost Tapestries of the City of Ladies. Christine de Pizan’s Renaissance Legacy

    OpenAIRE

    Le Ninan, Claire

    2008-01-01

    Dans ses œuvres didactiques, Christine de Pizan cherche, par divers procédés rhétoriques, à garantir la bonne réception de sa leçon ainsi que la pérennité de son œuvre, de ses idées et de son nom. Pourtant, la réelle influence des textes de Christine sur les princes et princesses de son époque est difficile à mesurer, si ce n’est par les catalogues de bibliothèque qui renseignent sur la présence des manuscrits dans la collection des personnages importants du royaume. De même, il est difficile...

  2. 75 FR 22012 - Endangered and Threatened Wildlife and Plants; 12-Month Finding on a Petition to List Susan's...

    Science.gov (United States)

    2010-04-27

    ... sedimentation associated with intensive livestock grazing can have a profound effect on aquatic... caddisfly's habitat downstream through vegetation removal, erosion, and subsequent downstream sedimentation... tank, then into seven float-controlled livestock tanks to draw the livestock away from riparian areas...

  3. The COlIStruction of the Self: A Developmental Perspective. Susan Harter. New York, NY: Guilford Press, 1999.

    Directory of Open Access Journals (Sweden)

    Sandra Leanne Bosacki

    1999-01-01

    Full Text Available Within the fields of educational and developmental psychology, interest has grown concerning the question of how cognitive and socioemotional processes work together to construct pathways for the self. In particular, researchers and educators have become increasingly interested in the role that the school plays in children's self-development. According to Jerome Bruner, "the single most universal thing about human experience is the phenomenon of the 'Self" (1996, p. 35 and advocates that education is crucial to its formation. However, despite the strong theoretical claims linking a child's sense of self to school experience, there has been a lack of systematic research on the self within the school context.

  4. Karma United

    DEFF Research Database (Denmark)

    Saliev, Kamolidden; Hockerts, Kai

    2013-01-01

    work with the company’s philanthropic activities. Moving on, the case describes the history of hummel and its turnaround in the 1990s from near bankruptcy. The leadership style in hummel International, 'Company Karma', is outlined and links are made to the general concept of corporate social...

  5. 76 FR 16613 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2011-03-24

    ... for Sustainable Fisheries, Northeast Region, NMFS (Assistant Regional Administrator), has made a.... SUPPLEMENTARY INFORMATION: An application for an EFP was submitted by the University of Maryland Eastern Shore (UMES) on February 18, 2011, in support of a project preliminarily selected under the New England and...

  6. 75 FR 58352 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Issuance of an...

    Science.gov (United States)

    2010-09-24

    ... fishing. SUMMARY: The Regional Administrator for Sustainable Fisheries, Northeast Region, NMFS, has issued a revised EFP in support of a drop chain small mesh net study conducted by the University of Rhode... temporarily retained for data collection purposes. Field work for this project began in April 2010, and 8 of...

  7. 75 FR 39178 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2010-07-08

    ..., cowcod, and yelloweye rockfish. Order on Remedy, Dkt. No. 342 (April 29, 2010) (Opinion). The Court held... Order on Remedy, Dkt. No. 342 (April 29, 2010). For darkblotched rockfish, NMFS notes that modifying the...

  8. 77 FR 5492 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2012-02-03

    ... the Atlantic surfclam and ocean quahog Georges Bank Closure Area. This would continue research to... testing to obtain additional data in locations where toxin levels may be higher than were present during the pilot phase of the study. NMFS has made a preliminary determination that the exempted fishing...

  9. 76 FR 65698 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2011-10-24

    ... Atlantic surfclam and ocean quahog Georges Bank Closure Area to continue testing the safety and efficacy of... research project that has been ongoing since 2006. NMS has made a preliminary determination that the...: http://www.nero.noaa.gov/sfd/clams . This project is a pilot program with the goal of determining if...

  10. 78 FR 34039 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-06-06

    ...) Georges Bank winter flounder. Sec. 648.86(l) Zero retention of Atlantic wolffish. Sec. 648.86(o..., fecundity, bioelectrical impedance analysis (BIA), food habits, and genetic research. The yellowtail... (GOM), Georges Bank (GB), Southern New England/Mid-Atlantic (SNE/MA)), or 1,200 fish total from each...

  11. 75 FR 37745 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-06-30

    ... rule; request for comments. SUMMARY: NMFS proposes to open a portion of the Georges Bank (GB) Closed... the presence of toxins known to cause paralytic shellfish poisoning (PSP). The U.S. Food and Drug... these trips to enter the food market. On January 21, 2010, NMFS received a letter from the FDA...

  12. 78 FR 21115 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-04-09

    ... monkfish for sale, but the sampling locations are determined by CCE. To conduct compensation fishing in... as to how the waiver could influence fishing behavior, and if it could increase the likelihood of an... white hake and witch flounder, which would be landed for commercial sale. All catch of Northeast...

  13. 78 FR 38692 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-06-27

    ... the influence of temperature on monkfish distribution and abundance. Regulations under the Magnuson... goal of this study is to investigate the influence of temperature on monkfish distribution and... use standard commercial gear and land monkfish for sale. Monkfish EFPs that waive possession limits...

  14. 77 FR 75057 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-12-19

    ... shell and egg-bearing lobsters. The commenters state that lobster fishing takes place in the southern... fewer dredges and shorter dredge time anticipated in an area of high biomass such as GB. This fishery is... from the three gears being used together in this area. However, because the biomass of surfclams and...

  15. 78 FR 66887 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-11-07

    ... optimum yield. This action would also continue to suspend the minimum shell size for Atlantic surfclams... still above the biomass target reference points. Based on this information, the Council is recommending...

  16. 78 FR 77005 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-12-20

    ... continues to suspend the minimum shell size for Atlantic surfclams for the 2014 fishing year. DATES: This... relatively low fishing mortality, the stock is still above the biomass target reference points. This action...

  17. 76 FR 53833 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-08-30

    ... management measures. * * * * * (c) * * * (1) * * * (ii) Differential trip landing limits and frequency limits based on gear type, closed seasons, and bycatch limits. Trip landing and frequency limits that differ by... Arena South Biogenic Area, Cordell Bank/Biogenic Area, Farallon Islands/Fanny Shoal, Half Moon Bay...

  18. The importance of a lasting impression / Linas Linkevicius ; interv. Steven Paulikas

    Index Scriptorium Estoniae

    Linkevicius, Linas

    2003-01-01

    Leedu kaitseminister Linas Linkevicius räägib rahvusvahelistes rahuvalveoperatsioonides osalemise tähtsusest, Leedu - USA tihedast koostööst ning käimasoleva presidendiskandaali mõjust Leedu rahvusvahelisele mainele

  19. The size of second chambers and European assemblies / Rein Taagepera, Steven P Recchia

    Index Scriptorium Estoniae

    Taagepera, Rein, 1933-

    2002-01-01

    Autorid võrdlevad eri maade esinduskogude kodade suurust ja elanike arvu neis maades ning arutlevad, kui suur kohtade arv peaks olema Euroopa Liidu Nõukogus ja Euroopa Parlamendis. Tabelid, diagrammid

  20. 77 FR 30486 - Confidentiality of Information; Magnuson-Stevens Fishery Conservation and Management...

    Science.gov (United States)

    2012-05-23

    ... information on three types of proposed changes. NMFS begins with proposed changes that concern the expanded... could be disclosed. This interpretation of limited access program would include specific types of... section 402(b)(1)(D). Unless expressly waived by Congress, sovereign immunity precludes state court...

  1. 75 FR 38030 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2010-07-01

    ... disruption to summer fisheries, as no additional restrictions to fishery management measures are necessary at... impacts within the lowered yelloweye rockfish OY in accordance with the court's order; makes routine in...

  2. 77 FR 67973 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2012-11-14

    ... the appropriate [sigma] value the Council chooses a P star (P*) based on its chosen level of risk aversion considering the scientific uncertainties. As the P* value is reduced, the probability of the ABC... additional reduction for scientific uncertainty beyond the sigma value reduction. A lower P* is more risk...

  3. 77 FR 26103 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-05-02

    ... communities, and will provide more flexibility for negotiating annual catches with Canada. 3. Overfishing... overfishing, rebuild overfished stocks, achieve optimum yield, and ensure that management measures are based... established accountability measures (AMs) for the 20 groundfish stocks in order to prevent overfishing of...

  4. 76 FR 12715 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2011-03-08

    ... and marketing evaluation and strategies; and outreach and implementation of the project results. The... devise strategies and means to efficiently harvest the redfish resource in the Gulf of Maine (GOM) while... in terms of their potential effects on results. Sources of variability include: Area fished; seasonal...

  5. Letters of Stone. From Nazi Germany to South Africa. Steven Robins ...

    African Journals Online (AJOL)

    merely hint at the gruesome reality in Nazi Germany. With the hindsight granted to present-day readers, we know the fate that awaited these men and women as an elongated and agonising social death reached its culmination in systematic mass murder. In describing his journeys to Germany,. Poland, Israel and the United ...

  6. 75 FR 81142 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-12-27

    ... and ocean quahogs from the Exclusive Economic Zone to prevent overfishing and to allow harvesting of... appropriate. The fishing quotas must be in compliance with overfishing definitions for each species. In... same ocean quahog overfishing definition. When the two quota amounts (ocean quahog and Maine ocean...

  7. 75 FR 18261 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-04-09

    ... programs for NE multispecies stocks newly classified as being overfished and subject to overfishing; and to... to end overfishing, rebuild overfished regulated NE multispecies and ocean pout stocks, and mitigate... and subject to overfishing, and that stocks currently classified as overfished require additional...

  8. 77 FR 65326 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-10-26

    ... to reduce overfishing occurring on Gulf of Maine cod in anticipation of further action to end overfishing in the 2013 fishing year. DATES: The expiration date of the temporary rule published May 1, 2012..., overfishing of GOM cod while the Council developed a rebuilding plan. In response to the Council request and...

  9. 78 FR 26277 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Biennial Specifications and...

    Science.gov (United States)

    2013-05-06

    ... harvest as intended by the Council in fisheries that are important to coastal communities in a manner that... actions need to be in effect. For the actions to be implemented in this final rule, affording the time... of the Pacific Coast Groundfish FMP goals and objectives of preventing overfishing and rebuilding...

  10. 76 FR 38313 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-06-30

    ... are available, preventing additional harvest in fisheries that are important to coastal communities... document and undergo proposed and final rulemaking before these actions need to be in effect. For the... delay could impair achievement of one of the Pacific Coast Groundfish FMP goals to prevent overfishing...

  11. 77 FR 18176 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-03-27

    ... Analyst, phone: 978-281-9257, fax: 978-281-9135. SUPPLEMENTARY INFORMATION: Background The NE Multispecies... acceptable biological catches (ABCs) and ACLs for regulated species and ocean pout, as well as distributing... (Framework 44) set the ABCs and ACLs for FYs 2010-2012. In 2011, Framework 45 to the NE Multispecies FMP...

  12. 78 FR 32375 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-05-30

    ... 02543-1026, or online at: www.nefsc.noaa.gov/nefsc/publications/ . The revised EFP would exempt vessels.... Category F vessels would be charged monkfish RSA DAS at a higher pro- rated rate of 2.909:1 RSA DAS for... tail-to-whole-weight conversion factor from 3.32 to 2.91, which essentially reduced the whole weight...

  13. 75 FR 65442 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-10-25

    ... increase in biomass and recruitment on Georges Bank and off Long Island, NY. Based on this information, the..., stock recruitment, projected fishing effort and catches, and areas closed to fishing. In June 2010, the... Quahogs \\3\\ 100,000 35,240 100,000 35,240 100,000 35,240 \\1\\ Numerical values are in millions except for...

  14. 78 FR 18187 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-03-25

    ... overfishing and was overfished. A new benchmark assessment (SARC 54) was completed for this stock in June 2012... stock was overfished. Final results from the February 2013 benchmark assessment for white hake are... Management Council (Council) as part of the biennial review process to respond to updated stock information...

  15. 78 FR 26171 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-05-03

    ... adopted an FY 2013 ABC for white hake based on the 2008 benchmark assessment for this stock, which was the... estimate current stock size and fishing mortality, and this model was approved at the last benchmark... hake benchmark stock assessment (SARC 56) was completed in February 2013. The results of the assessment...

  16. 78 FR 19367 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-03-29

    ... assessment for white hake was completed in 2008. A benchmark assessment for this stock was completed in... years (FYs) 2013-2015, including 2013 total allowable catches (TACs) for the three U.S./Canada stocks... management measures for this stock consistent with the proposed rebuilding strategy. This action also...

  17. 76 FR 23041 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-04-25

    ... updated peer-reviewed benchmark stock assessment conducted in July 2010 (Stock Assessment Workshop, or SAW..., including preventing overfishing, rebuilding overfished stocks, achieving optimum yield (OY), and minimizing... revises the biological reference points and stock status for pollock, updates annual catch limits (ACLs...

  18. 78 FR 26117 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-05-03

    ... monitor recruitment, benefits, insurance and taxes; logistical costs associated with deployment; and at..., such as logistical costs generated by deployment, which are outside its statutory obligations under the... measures in Framework 48: A provision for cost- sharing of monitoring costs between the industry and NMFS...

  19. 78 FR 32374 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2013-05-30

    ... surfclam/ocean quahog cage, and would allow project participants to test alternatives to the industry... applicant stated that offloading into cages can be burdensome and dangerous and the extra handling and the... proposed research and have minimal impacts that do not change the scope or impact of the initially approved...

  20. 78 FR 14226 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2013-03-05

    .... Amendment 16 also stated that each sector would develop an at-sea monitoring plan to monitor bycatch across... industry-funded at-sea monitoring program for sector trips targeting redfish with trawl nets with mesh... to have an observer or at-sea monitor on board. Mesh sizes are measured as described at 50 CFR 648.80...

  1. 77 FR 59883 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-10-01

    ... Atmospheric Administration (NOAA), Commerce. ACTION: Proposed rule; request for comments. SUMMARY: NMFS... border between the United States and Canada, the Hague Line, and is a U.S./Canada shared stock. The... promulgate emergency rules or interim measures ``to address the emergency or overfishing.'' (16 U.S.C. 1855(c...

  2. 75 FR 78619 - Shipping Act, Merchant Marine, and Magnuson-Stevens Fishery Conservation and Management Act...

    Science.gov (United States)

    2010-12-16

    ... that boat too much quota to catch. Response: FFP lending decisions and fishery management decisions are... FFP direct lending is subject to the above general credit standards and requirements found in Sec. Sec...) Credit decision. (1) The Program shall issue to approved applicants an AIP letter, which shall describe...

  3. 78 FR 49967 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-08-16

    ..., has been closed to the harvest of surfclams and ocean quahogs since 1990 due to red tide blooms that... surfclams and ocean quahogs since 1990 due to red tide blooms that cause PSP, without resulting in...; Fisheries of the Northeastern United States; Atlantic Surfclam and Ocean Quahog Fishery AGENCY: National...

  4. 77 FR 53164 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-08-31

    ... surfclams and ocean quahogs since 1990 due to red tide blooms that cause paralytic shellfish poisoning (PSP...; Fisheries of the Northeastern United States; Atlantic Surfclam and Ocean Quahog Fishery AGENCY: National... Area to the harvest of Atlantic surfclams and ocean quahogs. The area has been closed since 1990 due to...

  5. 77 FR 64488 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-10-22

    ... closed to the harvest of surfclams and ocean quahogs since 1990 due to red tide blooms that cause...; Atlantic Surfclam and Ocean Quahog Fishery AGENCY: National Marine Fisheries Service (NMFS), National... portion of the Georges Bank Closed Area to the harvest of Atlantic surfclams and ocean quahogs. The full...

  6. Valge Maja ökonomisti ülekuulamine / Austan Goolsbee ; intervjueerinud Steven D. Levitt, Stephen Dubner

    Index Scriptorium Estoniae

    Goolsbee, Austan

    2009-01-01

    Valge Maja ökonomist Austan Goolsbee vastab küsimustele, mis puudutavad riigi keskset kontrolli majanduse üle, maksumäära tõstmist rikkamatel maksumaksjatel, majanduskasvu juhtimist tulevikus, kultuurilisi muutusi, ideaalset maksumäära ning hüperinflatsiooni võimalikkust

  7. 78 FR 53363 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-08-29

    ... accounting concept as described in the FW 50 final rule and outlined in Sec. 648.87(b)(1)(i)(G)(1) through (5... Catch Entitlement (ACE) carryover accounting for FY2014 and beyond. For Sector Operations Plans: A...

  8. 78 FR 25214 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-04-30

    ... longer, which could increase interactions with protected resources and trigger additional management... action is necessary to help mitigate expected adverse economic and social harm resulting from substantial... biological, economic, and social impact analysis for this action are contained in the environmental...

  9. 78 FR 23733 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-04-22

    ..., Newburyport, MA 01950. The FEIS/RIR/IRFA is also accessible via the internet at http://www.nero.nmfs.gov . You... accept anonymous comments (enter ``N/A'' in the required fields if you wish to remain anonymous...

  10. 77 FR 2655 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2012-01-19

    ... or protected information. NMFS will accept anonymous comments (if submitting comments via the Federal Rulemaking portal, enter ``N/A'' in the relevant required fields if you wish to remain anonymous... Access This notice is accessible via the Internet at the Office of the Federal Register's Web site at...

  11. 78 FR 76570 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2013-12-18

    ... voluntarily by the sender will be publicly accessible. NMFS will accept anonymous comments (enter ``N/A'' in the required fields if you wish to remain anonymous). Attachments to electronic comments will be... . SUPPLEMENTARY INFORMATION: Electronic Access This document is accessible via the Internet at the Office of the...

  12. 75 FR 48920 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-08-12

    ... is also accessible via the Internet at http://www.nero.nmfs.gov . You may submit comments, identified... protected information. NMFS will accept anonymous comments (enter N/A in the required fields, if you wish to remain anonymous). You may submit attachments to electronic comments in Microsoft Word, Excel, Word...

  13. 75 FR 21189 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-04-23

    ..../Canada Management Area AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... announces a temporary closure of the Eastern U.S./Canada Area to limited access Northeast (NE) multispecies days-at-sea (DAS) vessels and a prohibition on the harvest, possession, and landing of Georges Bank (GB...

  14. ROBERT VENTURI, DENISE SCOTT BROWN Y STEVEN IZENOUR: LEARNING FROM LAS VEGAS

    Directory of Open Access Journals (Sweden)

    Ignacio Senra Fernández-Miranda

    2013-05-01

    Full Text Available RESUMEN Poco tiene que ver la edición original de 1972 de Learning from las Vegas, the forgotten symbolism of the architectural form, con la edición revisada de 1977, que fue traducida al español y publicada por Gustavo Gili en 1978. El gran formato del libro original (38x28cm se justificaba por la importancia del material gráfico desplegado, un ejercicio de análisis que aspiraba a descubrir nuevas técnicas de representación capaces de reproducir una realidad tan compleja sensorialmente como la de la ciudad de las Vegas. La drástica transformación, impulsada por los propios autores, suponía un abaratamiento y por tanto una mayor difusión del libro, pero sobretodo trataba de acabar con el conflicto entre su crítica al diseño Bauhaus y el diseño Bauhaus tardío del libro original, como señaló la propia Denise Scott Brown en el prologo de la edición revisada de 1977.

  15. Possible Role of Drugs and Herbal Medicines in Stevens-Johnson ...

    African Journals Online (AJOL)

    This paper has reviewed three cases of erythema multiforme major who presented with ocular complications. In one of the cases, the patient became blind because of mismanagement. The precipitating factors in the three patients were a herbal remedy, Fansidar® (Sulfadoxine 500mg; Pyrimethamine 25mg) and ...

  16. 76 FR 79122 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-12-21

    ... (50 CFR part 660, subparts C through G). Changes to current groundfish management measures implemented... Groundfish Fishery Management Measures The State of Washington manages canary and yelloweye rockfish under a... guidelines for canary and/or yelloweye rockfish. During 2011, the Washington State Department of Fish and...

  17. 77 FR 28497 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2012-05-15

    ... decrease in estimated current abundance from the prior assessment. The SRG met in Seattle, Washington, from... that the current modeling approach, which implements a relatively simple base case in the Stock...[deg] N. lat. The 2012 allocations of Pacific Ocean perch, canary rockfish, darkblotched rockfish, and...

  18. 76 FR 54713 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-09-02

    ... final rule and current codified regulations that resulted from incorrect amendatory instructions in the... bag limit is 10 RCG Complex fish per day coastwide. Retention of canary rockfish, yelloweye rockfish...

  19. 75 FR 75417 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2010-12-03

    ... more heavily towards the most recent year, to predict how current management measures will affect the... bycatch rate of co-occurring overfished species, primarily widow rockfish and canary rockfish, in the... initial testing of the jig gear, some additional catch of widow rockfish and canary rockfish is...

  20. 77 FR 22679 - Magnuson-Stevens Act Provisions; Fisheries off West Coast States; Biennial Specifications and...

    Science.gov (United States)

    2012-04-17

    ... (50 CFR part 660, subparts C through G). Changes to current groundfish management measures implemented... indicate that the probability of encountering canary rockfish, darkblotched rockfish, Pacific ocean perch...

  1. 75 FR 59143 - Magnuson-Stevens Fishery Conservation and Management Act; Regional Fishery Management Councils...

    Science.gov (United States)

    2010-09-27

    ... collection-of-information requirements contained in this rule may be submitted to Alan Risenhoover, Director... basis for salary of Council executive directors be put on par with that of NMFS Regional Administrators... broadened and clarified to include any income, grant, or other monetary or in-kind remuneration received by...

  2. 75 FR 34049 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-06-16

    ... as another product form due to processing and/or marketing reasons. The Council further states that... Sec. 648.322(b) of the proposed regulations would have exempted vessels targeting skate that also... sector vessels could increase targeting of skates by these vessels. Response: The Council's Amendment 3...

  3. 78 FR 579 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2013-01-03

    ... would not provide a viable targeting opportunity and will force fishers to target sablefish instead... action to reduce overall targeting of rockfish using hook and line gears, both commercial and... appropriate harvest levels while providing for fishing and marketing opportunities. Ultimately, taking the...

  4. Läbi tantsu kasvame suureks pereks / Steven Toomela, Gert Erik ; interv. Regina Lilleorg

    Index Scriptorium Estoniae

    Toomela, Steven

    2006-01-01

    Vabariikliku noorte tantsijate X suvelaagri lõputööna etendub vabaõhumuusikal "Kaua võib" (stsenarist Rünno Karna, muusika autor ja projektijuht Kalle Erm, kunstnik Rait Potisepp, dirigent Hirvo Surva). Püünsi põhikooli tantsulapsed sellest, mis laagris meeltmööda ja mis mitte. Vastab ka laste õpetaja Hele Pomerants

  5. 75 FR 15684 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2010-03-30

    ... all of the required information and warrants further consideration. Study Fleet projects are managed by the University of Massachusetts Dartmouth School of Marine Science and Technology (SMAST). The EFP... INFORMATION CONTACT: Jason Berthiaume, Fishery Management Specialist, (978) 281-9177. SUPPLEMENTARY...

  6. 76 FR 65181 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2011-10-20

    ... . SUPPLEMENTARY INFORMATION: The School for Marine Science and Technology at the University of Massachusetts... would be conducted by the School for Marine Science and Technology at the University of Massachusetts... preliminary determination that an exempted fishing permit application contains all of the required information...

  7. The Interpretive Constant: the Status of Material Objects in the Poetry of Wallace Stevens

    Directory of Open Access Journals (Sweden)

    Kacper Bartczak

    2012-01-01

    Full Text Available Stevens’s poems grant a curious status to material reality. Famously abstract, they refuse to abandon the realm of the material. Rather, “material reality” is inseparable from “abstract” concepts. Stevens’s position is pragmatist: the status and significance of material objects is founded by the entirely human linguistic/mental activity, which is also an interpretive activity. The poem is a site of initiating this activity. As such, Stevens’s poetics remains in opposition to other aesthetic posi­tions: the linguistic idealism of Mallarmé, the metaphysical realism of Miłosz and Herbert, and the material realism of Ponge and American “objectivists”. While the metaphysical positions tend to overcome the material, the realistic poets will reify it by “taking the side of things”. Stevens’s poetic pragmatism sees no lure in the extra-material, while also refusing to see matter as meaningful in itself, beyond the human interpretive activity.

  8. 77 FR 8780 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2012-02-15

    ... public that NMFS is extending the deadline to join a sector for FY 2012 through April 30, 2012. NMFS is..., Northeast Fishery Sector IV and Sustainable Harvest Sector 3 would operate as private lease-only sectors... require a different scheme for determining each permit's potential sector contribution. Sector vessels are...

  9. 76 FR 23076 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2011-04-25

    ..., fax (978) 281-9135. SUPPLEMENTARY INFORMATION: A proposed rule soliciting public comment on 19 sector... 3, will operate as private lease-only sectors. The Sustainable Harvest Sector 3 has not explicitly... leases among vessels within individual sectors, as well as between vessels in different sectors, was...

  10. 76 FR 28897 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-05-19

    ... TINSS and SS model revealed that: (1) Agreement in fit to the acoustic survey biomass was better between.... During the comment period, NMFS received four letters of comment. The U.S. Department of Interior... from the U.S. and Canadian fisheries; and biomass indices from the Joint U.S.-Canadian acoustic...

  11. Estonians Cast Wary Eye on Russiaþs Energy Empire / Steven Roman

    Index Scriptorium Estoniae

    Roman, Steven

    2006-01-01

    Euroopa, sh Eesti sõltuvus Venemaa energiaressurssidest ja energeetiline julgeolek. Diagramm: Gaasi kasutamine Eestis. Arvamust avaldavad majandus- ja kommunikatsiooniministeeriumi energeetika osakonna juhataja Einari Kisel ja parlamendisaadik Marko Mihkelson

  12. 76 FR 42663 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-07-19

    ... through daily Vessel Monitoring System (VMS) catch reports, as is currently proposed through a regulatory..., transfer, receive, sell, purchase, trade, or barter; or attempt to transfer, receive, sell, purchase, trade, or barter, or sell more than 2,000 lb (907 kg) of Atlantic [[Page 42670

  13. 76 FR 24444 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2011-05-02

    ... and were not sold, bartered or traded. At the time, DAS was the only effort control for the FMP, and... current system does not accurately account for the disposition of fish landed under the ``home consumption... receipt of the TSH report via a back-up system specified by the DSM service provider. While the...

  14. 76 FR 11381 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-03-02

    ... Fishery Management Plan (FMP), are intended to allow fisheries to access more abundant groundfish stocks.... Because of the restructuring, beginning on November 1, 2010, these specifications and management measures... complexity of the biennial specifications and management measures, the need for adequate National...

  15. 75 FR 61102 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2010-10-04

    ... opportunities to harvest available healthy stocks and meet the objective of the Pacific Coast Groundfish FMP to... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration 50 CFR Part 660 [Docket No... Coast Groundfish Fishery; Inseason Adjustments to Fishery Management Measures AGENCY: National Marine...

  16. 77 FR 24634 - Magnuson-Stevens Act Provisions; Fisheries off West Coast States; Biennial Specifications and...

    Science.gov (United States)

    2012-04-25

    ... specifications and management measures for most species of the Pacific Coast groundfish fishery (75 FR 67810... mortality of overfished and target species are the result of management measures designed to achieve, to the... rebuilding of overfished stocks by remaining within their rebuilding ACLs. Limited Entry Fixed Gear Fishery...

  17. 75 FR 15625 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2010-03-30

    ... Multispecies Fishery Management Plan (FMP) and is intended to increase the likelihood of harvesting the total... action is being taken to allow vessels to fully harvest the TACs for transboundary stocks of GB cod... Management Area through April 30, 2010, to facilitate the harvest of the TAC while ensuring that the TAC will...

  18. 76 FR 42577 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2011-07-19

    ... for FYs 2010 and 2011. 7. Multispecies Minimum Fish Sizes and Fillet Provisions The current... (ACE) for the sector in which that vessel participates. Currently, fillets and parts of fish as... limits. That is, the regulations require the weight of fillets or parts of fish to be multiplied by 3 and...

  19. 75 FR 23620 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2010-05-04

    ... based on a linear interpolation of the bycatch rates for widow rockfish from 2006-2009. From the overall... defined by the RFA (although some of these vessels may be affiliated with larger processing companies... processing companies). Tribal trawlers are presumed to be small entities, whereas the Tribes are presumed to...

  20. 77 FR 25623 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-05-01

    ... collaborating with the Council on the development of stock- rebuilding measures over the months to come. The... months and measures would be implemented for the May 1 start of the fishing year. For the cycle leading...

  1. 77 FR 19944 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2012-04-03

    ... its intent to address the rebuilding needs and NMFS anticipates collaborating with the Council on the... for the May 1 start of the fishing year. For the cycle leading into fishing year 2012, the Council and...

  2. 78 FR 16220 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2013-03-14

    ... States; Northeast Multispecies Fishery; 2013 Sector Operations Plans and Contracts and Allocation of Northeast Multispecies Annual Catch Entitlements AGENCY: National Marine Fisheries Service (NMFS), National..., provide allocations of Northeast (NE) multispecies to these sectors, and grant regulatory exemptions. We...

  3. 76 FR 10852 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2011-02-28

    ... States; Northeast Multispecies Fishery; 2011 Sector Operations Plans and Contracts, and Allocation of Northeast Multispecies Annual Catch Entitlements AGENCY: National Marine Fisheries Service (NMFS), National.... SUMMARY: As part of the process for the NMFS Northeast Regional Administrator approval of proposed sector...

  4. 78 FR 41772 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2013-07-11

    ... States; Northeast Multispecies Fishery; Proposed Rule To Allow Northeast Multispecies Sector Vessels.... ADDRESSES: A copy of the accompanying environmental assessment is available from the NMFS Northeast Regional.... SUPPLEMENTARY INFORMATION: Background Amendment 16 to the Northeast Multispecies Fisheries Management Plan...

  5. 78 FR 76077 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2013-12-16

    ... Northeastern United States; Northeast Multispecies Fishery; Final Rule To Allow Northeast Multispecies Sector... allows fishing access for Northeast multispecies sectors to two portions of the Southern New England... of the accompanying environmental assessment is available from the NMFS Northeast Regional Office...

  6. 78 FR 25591 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2013-05-02

    ... States; Northeast Multispecies Fishery; 2013 Sector Operations Plans and Contracts and Allocation of Northeast Multispecies Annual Catch Entitlements AGENCY: National Marine Fisheries Service (NMFS), National... year (FY) 2013, providing allocations of Northeast (NE) multispecies to these sectors, and granting 23...

  7. 75 FR 18113 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2010-04-09

    ... States; Northeast Multispecies Fishery; 2010 Sector Operations Plans and Contracts, and Allocation of Northeast Multispecies Annual Catch Entitlements AGENCY: National Marine Fisheries Service (NMFS), National... approval on a parallel track with Amendment 16 to the Northeast (NE) Multispecies Fishery Management Plan...

  8. Fundamentals of Condensed Matter Physics Marvin L. Cohen and Steven G. Louie

    Energy Technology Data Exchange (ETDEWEB)

    Devanathan, Ram

    2017-06-01

    This graduate level textbook on Condensed Matter Physics is written lucidly by two leading luminaries in this field. The volume draws its material from the graduate course in condensed matter physics that has been offered by the authors for several decades at the University of California, Berkeley. Cohen and Louie have done an admirable job of guiding the reader gradually from elementary concepts to advanced topics. The book is divided into four main parts that have four chapters each. Chapter 1 presents models of solids in terms of interacting atoms, which is appropriate for the ground state, and excitations to describe collective effects. Chapter 2 deals with the properties of electrons in crystalline materials. The authors introduce the Born-Oppenheimer approximation and then proceed to the periodic potential approximation. Chapter 3 discusses energy bands in materials and covers concepts from the free electron model to the tight binding model and periodic boundary conditions. Chapter 4 starts with fixed atomic cores and introduces lattice vibrations, phonons, and the concept of density of states. By the end of this part, the student should have a basic understanding of electrons and phonons in materials. Part II presents electron dynamics and the response of materials to external probes. Chapter 5 covers the effective Hamiltonian approximation and the motion of the electron under a perturbation, such as an external field. The discussion moves to many-electron interactions and the exchange-correlation energy in Chapter 6, the widely-used Density Functional Theory (DFT) in chapter 7, and the dielectric response function in Chapter 8. The next two parts of the book cover advanced topics. Part III begins with a discussion of the response of materials to photons in Chapter 9. Chapter 10 goes into the details of electron-phonon interactions in different materials and introduces the polaron. Chapter 11 presents electron dynamics in a magnetic field and Chapter 12 discusses electrical and thermal transport in materials. Part IV takes the reader further into many body effects, superconductivity, and nanoscale materials. The authors introduce Feynman diagrams and many-body perturbation theory in Chapter 13, theories of superconductivity in Chapter 14, magnetism in Chapter 15, and low dimensional systems in Chapter 16. The first two parts are required reading for the beginner planning to perform DFT calculations. The advanced student interested in conducting research in condensed matter physics will benefit from continuing on to the last two parts. There is a set of problems at the end of each part. The narrative is aided by equations and detailed figures. References at the end of the book direct the reader to relevant books and review articles for each chapter. The inside covers include a periodic table and a useful list of fundamental physical constants. The authors present the underlying mathematics elegantly, which makes the textbook quite readable for those with a good mathematical background. Students lacking a firm footing in math will find the terrain rough after Chapter 1. This field has seen many good undergraduate textbooks including those by Kittel and by Ashcroft and Mermin. This volume fills the need for a rigorous graduate level textbook, and is a required addition to the bookshelf of every condensed matter physicist. Cohen and Louie have brought refreshing clarity to a challenging subject and made it eminently accessible to the motivated student.

  9. 78 FR 43066 - Magnuson-Stevens Act Provisions; National Standard 2-Scientific Information

    Science.gov (United States)

    2013-07-19

    ... definition of BSIA should be avoided due to the dynamic nature of science. Therefore, as recommended by the... impact of this action on current Council peer review practices should be minimal because the peer review..., social and economic impacts of management measures, and sustainability of fishing practices.'' Id. 16 U.S...

  10. 75 FR 65660 - Steven B. Brown, M.D.; Revocation of Registration

    Science.gov (United States)

    2010-10-26

    ... that he was using his relationship as a physician with a patient to divert medication for his own use... a corollary, [it] also bars doctors from peddling to patients who crave the drugs for those... units to patients'' and that he ``received half the dosage units back from the patients after the...

  11. 76 FR 21861 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

    Science.gov (United States)

    2011-04-19

    ... fishery, including a requirement for independent, third-party dockside and at-sea monitoring of sector...; Approved Sector Monitoring Service Providers AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notification of NMFS-approved sector...

  12. When "Emily Dickinson" Met "Steven Spielberg": Assessing Social Information Processing in Literacy Contexts.

    Science.gov (United States)

    Donahue, Mavis L.; Szymanski, Carol M.; Flores, Christine Wujek

    1999-01-01

    Uses current research and theory to frame the peer interactions of "Emily Dickinson," a 16-year-old with oral-language problems and social isolation. Classroom-based assessment revealed an interaction pattern in which Emily used her strong literacy interests and skills to initiate and mediate social interaction with peers, including another gifted…

  13. 76 FR 79612 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-12-22

    ... state-operated permit banks for the purpose of maximizing the fishing opportunities made available by... activity to regain their DAS for that trip, providing another opportunity to profit from the DAS that would... entities. Further, no reductions in profit are expected for any small entities, so the profitability...

  14. 78 FR 48852 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-08-12

    ... envelope, ``Comments on MSB Amendment 14 NOA.'' Fax: (978) 281-9135, Attn: Aja Szumylo. Instructions... compromises the safety of the vessel, (2) mechanical failure prevents the catch from being brought aboard, or... slipping was safety or mechanical failure, would be required to return to port. This aspect of the measure...

  15. 76 FR 17109 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Extension for...

    Science.gov (United States)

    2011-03-28

    ... tagging, and model development to better evaluate the growth and reproductive performance of the... to initial logistical delays and additional time to complete research and funding components of this... study remain consistent with the Atlantic Deep-Sea Red Crab Fishery Management Plan. If approved, the...

  16. 75 FR 67809 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2010-11-03

    ... economic benefits, create individual economic stability, provide full utilization of the trawl sector... taken in the U.S. exclusive economic zone (EEZ) off the coasts of Washington, Oregon, and California... holistic alternatives relative to the biological and socio-economic environment and consistent with the...

  17. 75 FR 67083 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2010-11-01

    ... Research program. The primary objective of this study is to assess the effects of different stressors on... Reflex Action Mortality Predictors (RAMP) under different stressors to assess the discard mortality rates... research landings from the VTRs in their ACE accounting, in addition to the vessel's dealer-recorded...

  18. Sõrve 2008 / Nicholas Wurm, Steven Buchert, Mai Buchert, Sandra Buchert...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    lapsed ja lapsevanemad Austraaliast meenutavad oma viibimist Sõrve lastelaagris: This is a story of a family from Sõrve; Nicholas Wurm - Age 9 (Adelaide); Alan and Debbie Mikkor (Melbourne); Jesse Mikkor's point of view: Age 8; Lauren Mikkor's point of view: Age 13

  19. 76 FR 27507 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2011-05-11

    ... communities. The court upheld the integrated or holistic approach used to develop the harvest levels for all... Amendment 16-4. The Council, continuing the integrated or holistic approach developed in Amendment 16-4 and...:01-cv-00421-JLI. Review of recent catch levels as well as trends in the economic health of the...

  20. 76 FR 16595 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-03-24

    ..., including an adjustment to the overfishing definition, modification of the essential fish habitat (EFH... some IFQ separate from the vessel's LAGC permit; Revision of the essential fish habitat (EFH) closures...

  1. 76 FR 19929 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-04-11

    ..., including: A revision of the overfishing definition (OFD); modification of the essential fish habitat (EFH... by LAGC vessels as they continue to fish would count toward that stock area's sub-ACL for the scallop...: Fishing [[Page 19934

  2. 78 FR 72586 - Magnuson-Stevens Act Provisions; Fisheries off West Coast States; Biennial Specifications and...

    Science.gov (United States)

    2013-12-03

    ... stable trip limit approach for these fisheries will help provide consistency, safety, and predictability... available data. A stable trip limit approach will help provide consistency, safety, and predictability to... exceed, annual catch limits (ACLs) of target species; and to foster the rebuilding of overfished stocks...

  3. 78 FR 54442 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-09-04

    ... developed by the Council to modify the accountability measures for the Atlantic mackerel, Atlantic bluefish... mackerel, butterfish, Atlantic bluefish, summer flounder, scup, black sea bass, golden tilefish, ocean...

  4. 76 FR 60605 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-09-29

    ... Bluefish FMP; Amendment 2 to the Spiny Dogfish FMP; Amendment 15 to the Summer Flounder, Scup, and Black... developing ABC recommendations for the summer flounder, scup, and bluefish stocks. NMFS disagrees that the...

  5. 78 FR 76759 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-12-19

    ... amendment changes the accountability measures for the Atlantic mackerel, Atlantic bluefish, summer flounder... catch Atlantic mackerel, butterfish, Atlantic bluefish, summer flounder, scup, black sea bass, golden... bass and a single-year point estimate from MRIP for the Atlantic bluefish and mackerel fisheries...

  6. 78 FR 57341 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-09-18

    ... amendment proposes to change the accountability measures for the Atlantic mackerel, Atlantic bluefish... mackerel, butterfish, Atlantic bluefish, summer flounder, scup, black sea bass, golden tilefish, ocean.... (Note, Atlantic mackerel and bluefish currently use only a single-year comparison.) The Council also...

  7. 76 FR 35577 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2011-06-17

    ..., the Council decided to amend the Atlantic Mackerel, Squids, and Butterfish; Atlantic Bluefish; Spiny... Bluefish FMP; Amendment 2 to the Spiny Dogfish FMP; Amendment 15 to the Summer Flounder, Scup, and Black... subsequent fishing year. Atlantic Bluefish. The Council's proposed approach for bluefish would establish a...

  8. Iridium concentration and noble gas composition of Cretaceous-Tertiary boundary clay from Stevens Klint, Denmark

    International Nuclear Information System (INIS)

    Osawa, Takahito; Hatsukawa, Yuichi; Nagao, Keisuke; Koizumi, Mitsuo; Oshima, Masumi; Toh, Yosuke; Kimura, Atsushi; Furutaka, Kazuyoshi

    2009-01-01

    The Cretaceous-Tertiary (K-T) boundary about 65 million years ago records a mass extinction event caused by a bolide impact. K-T boundary clay collected from Stevns Klint, Denmark was investigated in this work. Iridium concentrations of eight clays across the K-T boundary were determined using a multiple gamma-ray analysis system after neutron activation. Anomalously high Ir concentrations were detected in five marl samples, with the highest concentration being 29.9 ppb. Four samples were analyzed for all noble gases. NO extraterrestrial Ar, Kr, and Xe were discovered in any of the samples, although most of the 3 He which was detected was extraterrestrial. Solar-like Ne was observed only in the sample SK4, which had an Ir concentration of 14.3 ppb, indicating the presence of micrometeorites. The solar-like Ne clearly did not originate from an asteroid/comet associated with the bolide impact, as that asteroid is thought to have been extremely large. Also, because there was no sign of a high accretion rate of micrometeorites at the boundary it could not be ascertained whether the solar-like Ne was related to a catastrophic event that led to the extinction of the dinosaurs. (author)

  9. 77 FR 10466 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2012-02-22

    ... fishery is managed under an individual fishing quota system. In the mothership sector, catcher vessels deliver to floating processors called motherships. This fishery is managed under a single mothership co-op... fishermen opportunities to sustainably harvest over 90 species of groundfish managed under the FMP. Since...

  10. Kanono refrakcija Antonios Susanos Byatt romane Apsėdimas | Refraction of the Canon in Antonia Susan Byatt’s Novel Possession

    Directory of Open Access Journals (Sweden)

    Regina Rudaitytė

    2005-01-01

    Full Text Available The article focuses on the revision and transformation of the genre of romance, particularly in its 19th century poetical form, actualized in A. S. Byatt’s novel Possession through an enormous intertextual web of references. The major intertext in the novel is Victorian literature and culture on which Byatt concentrates, covering the whole romance canon through intertextual references to Romantic poetry and to the tradition of medieval romances in their Victorian rewritings.The play with the conventions of the genre of romance and its transformations, the pastiches of the Victorian poetry are the main narrative strategies for Byatt to achieve the refraction of the canon – a re-evaluation of the Victorian poetic tradition from the contemporary feminist and poststructuralist perspective.

  11. Susan J. Slaughter, Lora D. Delwiche, The Little SAS Book for Enterprise Guide 4.1 et James B. Davis, Statistics using SAS Enterprise Guide

    OpenAIRE

    2010-01-01

    Le logiciel SAS® (Statistical Analysis System) est un logiciel d’analyse statistique et économétrique de référence en économie industrielle ; il permet de gérer de grandes bases de données informatiques indépendamment de leur format ou de leur plate-forme de résidence, de réaliser quasiment tous les traitements économétriques sur ces données, et de mettre en forme les résultats. Un obstacle à son utilisation a souvent résidé pour beaucoup dans la relative complexité des outils de programmatio...

  12. Interview with a quality leader: Kent Bottles, MD, president of ICSI, on transforming care for the future. Interview by Susan V. White.

    Science.gov (United States)

    Bottles, Kent

    2010-01-01

    Kent Bottles, MD, President of the Institute for Clinical Systems Improvement (ICSI). Dr. Bottles is a board-certified pathologist who specialized in surgical and cyto-pathology. He earned a medical degree from Case Western Reserve University in Ohio. He has extensive experience in integrated healthcare delivery systems, research, academia, commercial laboratories, genomics, proteomics, and management of biotech start-up companies. Dr. Bottles was vice president and chief medical officer of the Iowa Health System. Before that, he served as president and CEO of Grand Rapids Medical Education and Research Center for Health Professions, a multi-institutional consortium of healthcare organizations, and as president of Genomics Repository and chief knowledge officer, Genomics Collaborative Inc. Dr. Bottles has extensive academic experience, serving as Professor and Acting Head, Department of Pathology and Laboratory Medicine at the University of Iowa. He was also the founding medical director of managed care plans for University of Iowa employees. Dr. Bottles has addressed topics ranging from quality and patient safety and disruptive technology to patient-physician relationships and the future of medicine. He has received numerous honors, including the Rodney T. West Literary Achievement Award for the most important article on medical management presented by the American College of Physician Executives. He has broad clinical experience with the University of Iowa and the San Francisco General Hospital, and has been a national leader in changing the practice of pathology and laboratory medicine to meet the challenges of managed care.

  13. Breast cancer patients' perspectives on and use of complementary and alternative medicine: a study by the Susan G. Komen Breast Cancer Foundation.

    Science.gov (United States)

    Astin, John A; Reilly, Colleen; Perkins, Cheryl; Child, Wendy L

    2006-01-01

    The purpose of this study was to examine patterns and predictors of complementary and alternative medicine (CAM) among breast cancer patients. A review of the existing survey literature on CAM use for breast cancer was conducted with a series of eight focus groups (N = 67) to further examine the perspectives of breast cancer patients on CAM. The rates of CAM use varied from 17 to 75%, with a mean of 45%. Vitamins and minerals and herbs were the most frequently cited categories. Users tended to be younger, more educated, and more likely to have used CAM prior to their diagnosis. Focus group data indicate that breast cancer patients use a wide array of CAM for a variety of reasons, including symptom management, improving quality of life, and enhancing immune function. Although women rely on a variety of resources for information, they frequently experience frustration owing to the absence or conflicting nature of such information. Communication with conventional providers about CAM is frequently experienced as either unsupportive or not helpful by many patients. The results point to the value of developing better evidence-based informational resources related to CAM and cancer and the need for physicians to become better educated about CAM and how to communicate more effectively with their breast cancer patients about it.

  14. INDXENDF, Preparation of Visual Catalogue of ENDF Format Data

    International Nuclear Information System (INIS)

    Silva, Orion de O.; Paviotti Corcuera, R.; De Moraes Cunha, M.; Ferreira, P.A.

    1996-01-01

    1 - Description of program or function: This program is a video catalogue for libraries in the ENDF-4, ENDF-5 or ENDF-6 format (Evaluated Nuclear Data File) which can be run on an IBM-PC or compatible computer. This user friendly catalogue is of interest to nuclear and reactor physics researchers. The input is the filename of ENDF data and the two output files contain: i. the list of materials with corresponding laboratory, author and date of evaluation; ii. information about the MF and MT numbers for each material. The program is written in the C language whose capability of providing windows and 'interrupts' along with speed and portability, has been greatly exploited. The system allows output of options (i) and (ii) either on screen, printer or hard disk. 2 - Method of solution: The source code of about 3000 lines was written in C. The routines for windowing were based on the following works: Hummel (1988), Stevens (1989), Lafore (1987), Borland International (1988a, 1988b) and Schildt (1988, 1989). 3 - Restrictions on the complexity of the problem: The executable program occupies about 52 Kb of memory. The extra hard disk space needed depends upon the size of the ENDF/B data file to be processed (e.g. the Activation file contains about 1.3 M-bytes, the General Purpose ENDF/B-VI has four parts, each containing about 12 M-bytes). To run the program the 'datafile' and the executable code '.EXE' file should be on the hard-drive. The program may be run on any IBM/PC or compatible with at least 640 Kb RAM

  15. Personal recommender systems for learners in lifelong learning: requirements, techniques and model

    NARCIS (Netherlands)

    Drachsler, Hendrik; Hummel, Hans; Koper, Rob

    2007-01-01

    Drachsler, H., Hummel, H. G. K., & Koper, R. (2008). Personal recommender systems for learners in lifelong learning: requirements, techniques and model. International Journal of Learning Technology, 3(4), 404-423.

  16. Recommender Systems in Technology Enhanced Learning

    NARCIS (Netherlands)

    Manouselis, Nikos; Drachsler, Hendrik; Vuorikari, Riina; Hummel, Hans; Koper, Rob

    2010-01-01

    Manouselis, N., Drachsler, H., Vuorikari, R., Hummel, H. G. K., & Koper, R. (2011). Recommender Systems in Technology Enhanced Learning. In P. B. Kantor, F. Ricci, L. Rokach, & B. Shapira (Eds.), Recommender Systems Handbook (pp. 387-415). Berlin: Springer.

  17. Educational Modelling Language and Learning Design: new challenges for instructional re-usability and personalized learning

    NARCIS (Netherlands)

    Hummel, Hans; Manderveld, Jocelyn; Tattersall, Colin; Koper, Rob

    2003-01-01

    Published: Hummel, H. G. K., Manderveld, J. M., Tattersall, C.,& Koper, E. J. R. (2004). Educational Modelling Language: new challenges for instructional re-usability and personalized learning. International Journal of Learning Technology, 1, 1, 110-111.

  18. Identifying the Goal, User model and Conditions of Recommender Systems for Formal and Informal Learning

    NARCIS (Netherlands)

    Drachsler, Hendrik; Hummel, Hans; Koper, Rob

    2008-01-01

    Drachsler, H., Hummel, H. G. K., & Koper, R. (2009). Identifying the Goal, User model and Conditions of Recommender Systems for Formal and Informal Learning. Journal of Digital Information, 10(2), 4-24.

  19. Collaboration Scripts for Mastership Skills: Online game about classroom dilemmas in teacher education

    NARCIS (Netherlands)

    Hummel, Hans; Geerts, Walter; Slootmaker, Aad; Kuipers, Aad; Westera, Wim

    2013-01-01

    Hummel, H. G. K., Geerts, W. M., Slootmaker, A., Kuipers, D., & Westera, W. (in press). Collaboration scripts for mastership skills: Online game about classroom dilemmas in teacher Education. Interactive Learning Environments.

  20. Environmental Assessment for Phase 8 of Military Family Housing, Mountain Home Air Force Base, Idaho

    Science.gov (United States)

    2007-03-01

    Hummel as a partner and it is from this late 19th century beginning that the current architectural firm of Hummel Architects in Boise, Idaho was...Georgian/Box style housing units (MHAFB 2005). As currently planned, housing units constructed in the Greenbrier neighborhood would be of a Victorian ...Vernacular style (Figure 3). Architectural characteristics associated with the Victorian Vernacular style include: high pitched gable roofs

  1. Characterization of Fish Sauce Aroma Impact Compounds Using GC-MS, SPME-Osme-GCO, and Stevens' Power Law Exponents

    Science.gov (United States)

    The objectives of this study were to characterize volatile compounds and to determine the characteristic aromas associated with impact compounds in 4 fish sauces using solid-phase micro-extraction, gas chromatography-mass spectrometry, Osme, and gas chromatography olfactometry (SPME-Osme-GCO) couple...

  2. I Am Not Captain Dunsel! A (Former) Head of an Academic Branch Library Replies to Steven Bell

    Science.gov (United States)

    Redalje, Susanne J.

    2009-01-01

    For those unfamiliar with Star Trek, "Dunsel" was a term introduced in the episode titled "The Ultimate Computer." It is a term used by Star Fleet cadets to refer to an entity that serves no useful purpose, in this case a human who has been replaced by a machine. The episode touches on finding the best balance between human and machine to run a…

  3. Pühapäeva hommik : [luuletused] / Wallace Stevens ; tõlk. Hasso Krull, Märt Väljataga

    Index Scriptorium Estoniae

    Stevens, Wallace

    2008-01-01

    Sisu: Pühapäeva hommik ; Peter Quince klahvide ees ; Mozart, 1935 ; Postkaart vulkaanist ; Moodsast luulest ; Paks punane mees loeb ette ; Seesmise armukese viimane üksikõne ; Ühe üksikasja kulg. Elu- ja loomeloolisi andmeid autori kohta lk. 531-532

  4. Kõik ajaplaneerimisjamad on pärit lapsepõlvest! / Steven Berglas ; tõlk. Marko Uibu

    Index Scriptorium Estoniae

    Berglas, Steven

    2005-01-01

    Autori hinnangul aja väärkasutajate probleem ei olegi niivõrd oskamatuses oma aega kasutada, vaid pigem vähene eneseusk ning alateadlik hirm, et tema tööle pannakse mingi hinnang. Neljast ajakasutaja tüübist. Kommenteerib psühhoterapeut Endel Talvik

  5. Steven Bochco could kick Shakespeare’s ass”. The Simpsons’ attack on the Shakespeare myth

    Directory of Open Access Journals (Sweden)

    Maria Elisa Montironi

    2014-07-01

    Full Text Available This paper aims at describing the ways in which the Shakespeare myth is dealt with by The Simpsons, the worldwide successful American sit-com which since 1990 has depicted and reflected upon contemporary society, including its relation to and the institutionalization of literary canons, such as the Shakespearean one. In this investigation, The Simpsons will be considered as a trans-medial phenomenon, including, besides the celebrated sit-com, also the Simpsons based adaptation of Shakespeare’s Macbeth created and performed by Rick Miller (2002, the video games that feature the famous yellow-skinned characters, and the comic book series entitled Simpsons Comics. After a brief theoretical introduction, this paper will illustrate how the Shakespeare myth is de-mythologized through The Simpsons, to be re-mythologized so as to function and be meaningful in our contemporary world. In the conclusion, an attempt will be made to answer the extremely complex question about the political effectiveness of these acts.

  6. 77 FR 65639 - Magnuson-Stevens Act Provisions; Fisheries Off the West Coast States; Pacific Coast Groundfish...

    Science.gov (United States)

    2012-10-30

    ... Information or otherwise sensitive or protected information. NMFS will accept anonymous comments (if... wish to remain anonymous). Attachments to electronic comments will be accepted in Microsoft Word, Excel... INFORMATION: Electronic Access This document is accessible via the Internet at the Office of the Federal...

  7. Steven Charles Curtis, "An Observational Analysis of Successful Junior High/Middle School General Music Teachers." A Review.

    Science.gov (United States)

    Wing, Lizabeth

    1989-01-01

    Reviews a doctoral dissertation that attempts to identify and analyze the behavior of successful middle school music teachers. Describes the instrument developed to measure these behavioral characteristics. Suggests that the videotapes of class sessions may be the most useful portion of the study. (LS)

  8. Brigadier General James Stevens Simmons (1890-1954), Medical Corps, United States Army: a career in preventive medicine.

    Science.gov (United States)

    Marble, Sanders

    2012-02-01

    James Simmons began his career in the US Army as a laboratory officer and his assignments progressed into tropical medicine research. His interests and work evolved into preventive medicine (PM, as the Army termed public health), and he took both a PhD and a Doctorate in Public Health. As the Army's leading PM officer he was appointed head of PM in 1940 and guided the Army's PM effort through World War II. His responsibility ran from gas masks through healthy nutrition and occupational health to an enormous variety of diseases; by the war's end, the breadth and importance of PM was reflected in the Preventive Medicine Division, having fully one-sixth of all military personnel at the Surgeon General's Office. Simmons used his strong professional credentials to tap into civilian medicine for expertise the Army lacked and he established organizations that survive to this day. After retirement, he sought to expand the field of public health and raise another generation of public health physicians.

  9. The Consequences of Disobeying the Patriarchal Values in Niki Caro's North Country and Steven Soderbergh's Erin Brockovich

    OpenAIRE

    Puspa, Jessica; Handojo, Priska Febrinia

    2013-01-01

    This study aims to understand the consequences that Josey Aimes and Erin Brockovich face in disobeying the patriarchal values in North Country and Erin Brockovich. Patriarchal society where Aimes and Brockovich live, demands that the roles of women are as domestic creatures. If they cannot accept their roles, as the consequences, they will be punished by the people who guard the patriarchal values. It can be seen that Aimes and Brockovich are still bound by the patriarchal values which inhibi...

  10. 77 FR 2720 - Proposed Agreement and Covenant Not To Sue for the Colville Post & Poles Superfund Site, Stevens...

    Science.gov (United States)

    2012-01-19

    .... MacDonald, Assistant Regional Counsel, U.S. Environmental Protection Agency, Region 10, 1200 Sixth Avenue, Suite 900, Seattle, Washington 98101; fax: (206) 553-1762; email: MacDonald[email protected] . FOR FURTHER INFORMATION CONTACT: Jennifer G. MacDonald, Assistant Regional Counsel, U.S. Environmental...

  11. Varjatud ajalugu ehk kuidas eksiilkunst kodu leidis = Hidden history, or how an exiled art found a home / Steven Mansbach

    Index Scriptorium Estoniae

    Mansbach, Steven, 1950-

    2009-01-01

    Euroopa 20. saj. kunsti ajaloo õpetamisest Ameerikas. Pärast Teist maailmasõda Ameerikasse emigreerunud kunstiteadlaste tegevusest. Ignoreerivast suhtumisest Ida-Euroopa maade kunsti. Geograafiliste, ajaliste ja kultuuriliste eripärade ületamise vajadusest

  12. Serum insulin-like growth factor (IGF)-I and IGF binding protein-3 in relation to terminal duct lobular unit involution of the normal breast in Caucasian and African American women: The Susan G. Komen Tissue Bank.

    Science.gov (United States)

    Oh, Hannah; Pfeiffer, Ruth M; Falk, Roni T; Horne, Hisani N; Xiang, Jackie; Pollak, Michael; Brinton, Louise A; Storniolo, Anna Maria V; Sherman, Mark E; Gierach, Gretchen L; Figueroa, Jonine D

    2018-02-22

    Lesser degrees of terminal duct lobular unit (TDLU) involution, as reflected by higher numbers of TDLUs and acini/TDLU, are associated with elevated breast cancer risk. In rodent models, the insulin-like growth factor (IGF) system regulates involution of the mammary gland. We examined associations of circulating IGF measures with TDLU involution in normal breast tissues among women without precancerous lesions. Among 715 Caucasian and 283 African American (AA) women who donated normal breast tissue samples to the Komen Tissue Bank between 2009 and 2012 (75% premenopausal), serum concentrations of IGF-I and binding protein (IGFBP)-3 were quantified using enzyme-linked immunosorbent assay. Hematoxilyn and eosin-stained tissue sections were assessed for numbers of TDLUs ("TDLU count"). Zero-inflated Poisson regression models with a robust variance estimator were used to estimate relative risks (RRs) for association of IGF measures (tertiles) with TDLU count by race and menopausal status, adjusting for potential confounders. AA (vs. Caucasian) women had higher age-adjusted mean levels of serum IGF-I (137 vs. 131 ng/mL, p = 0.07) and lower levels of IGFBP-3 (4165 vs. 4684 ng/mL, p IGF-I:IGFBP-3 ratios were associated with higher TDLU count in Caucasian (RR T3vs.T1 =1.33, 95% CI = 1.02-1.75, p-trend = 0.04), but not in AA (RR T3vs.T1 =0.65, 95% CI = 0.42-1.00, p-trend = 0.05), women. Our data suggest a role of the IGF system, particularly IGFBP-3, in TDLU involution of the normal breast, a breast cancer risk factor, among Caucasian and AA women. © 2018 UICC.

  13. The Practice of Nursing Research: Appraisal, Synthesis, and Generation of Evidence - Seventh edition Grove Susan K The Practice of Nursing Research: Appraisal, Synthesis, and Generation of Evidence - Seventh edition 752pp Elsevier 9781455707362 1455707368 [Formula: see text].

    Science.gov (United States)

    2013-04-03

    This classic research text has been updated for nursing students and those in nursing practice. Though a substantial book, it is easy to dip in and out of, covering a wide range of topics from the research process and analysing data to sampling and seeking funding.

  14. Stevens Pond: A postglacial pollen diagram from a small Typha Swamp in Northwestern Minnesota, interpreted from pollen indicators and surface samples

    NARCIS (Netherlands)

    Janssen, C.R.

    1967-01-01

    The pollen assemblages of a core in the coniferhardwood formation in northwestern Minnesota are compared with the floristics of the recent vegetation in the region. Percentage levels of the main tree components have been compared first with those from recent surface samples taken at the same short

  15. Determination of premining geochemical background and delineation of extent of sediment contamination in Blue Creek downstream from Midnite Mine, Stevens County, Washington

    Science.gov (United States)

    Church, Stan E.; Kirschner, Frederick E.; Choate, LaDonna M.; Lamothe, Paul J.; Budahn, James R.; Brown, Zoe Ann

    2008-01-01

    Geochemical and radionuclide studies of sediment recovered from eight core sites in the Blue Creek flood plain and Blue Creek delta downstream in Lake Roosevelt provided a stratigraphic geochemical record of the contamination from uranium mining at the Midnite Mine. Sediment recovered from cores in a wetland immediately downstream from the mine site as well as from sediment catchments in Blue Creek and from cores in the delta in Blue Creek cove provided sufficient data to determine the premining geochemical background for the Midnite Mine tributary drainage. These data provide a geochemical background that includes material eroded from the Midnite Mine site prior to mine development. Premining geochemical background for the Blue Creek basin has also been determined using stream-sediment samples from parts of the Blue Creek, Oyachen Creek, and Sand Creek drainage basins not immediately impacted by mining. Sediment geochemistry showed that premining uranium concentrations in the Midnite Mine tributary immediately downstream of the mine site were strongly elevated relative to the crustal abundance of uranium (2.3 ppm). Cesium-137 (137Cs) data and public records of production at the Midnite Mine site provided age control to document timelines in the sediment from the core immediately downstream from the mine site. Mining at the Midnite Mine site on the Spokane Indian Reservation between 1956 and 1981 resulted in production of more than 10 million pounds of U3O8. Contamination of the sediment by uranium during the mining period is documented from the Midnite Mine along a small tributary to the confluence of Blue Creek, in Blue Creek, and into the Blue Creek delta. During the period of active mining (1956?1981), enrichment of base metals in the sediment of Blue Creek delta was elevated by as much as 4 times the concentration of those same metals prior to mining. Cadmium concentrations were elevated by a factor of 10 and uranium by factors of 16 to 55 times premining geochemical background determined upstream of the mine site. Postmining metal concentrations in sediment are lower than during the mining period, but remain elevated relative to premining geochemical background. Furthermore, the sediment composition of surface sediment in the Blue Creek delta is contaminated. Base-metal contamination by arsenic, cadmium, lead, and zinc in sediment in the delta in Blue Creek cove is dominated by suspended sediment from the Coeur d?Alene mining district. Uranium contamination in surface sediment in the delta of Blue Creek cove extends at least 500 meters downstream from the mouth of Blue Creek as defined by the 1,290-ft elevation boundary between lands administered by the National Park Service and the Spokane Indian Tribe. Comparisons of the premining geochemical background to sediment sampled during the period the mine was in operation, and to the sediment data from the postmining period, are used to delineate the extent of contaminated sediment in Blue Creek cove along the thalweg of Blue Creek into Lake Roosevelt. The extent of contamination out into Lake Roosevelt by mining remains open.

  16. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    International Nuclear Information System (INIS)

    Goyal, Amit

    2012-01-01

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R and D resulted in 7 R and D 100 Awards including the 2010 R and D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  17. Quality of water in an inactive uranium mine and its effects on the quality of water in Blue Creek, Stevens County, Washington, 1984-85. Water Resources Investigation

    International Nuclear Information System (INIS)

    Sumioka, S.S.

    1991-01-01

    The purpose of the report is to present the results of a study done to determine (1) the monthly and annual water budgets and probable variation in runoff for the drainage basin in which the mine is located; (2) if precipitation is the source of low pH water found in pit 3 and the retention pond; (3) the quality of water in pits 3 and 4, the retention pond, streamflow from the basin, Blue Creek upstream and downstream of the point the drainage enters, and near the mouth of Blue Creek; (4) the quality of ground water discharged from the basin into Blue Creek; and (5) the daily mean values of discharge, water temperature, specific conductance, and pH for mine drainage from the basin, Blue Creek upstream and downstream of the mine drainage, and near the mouth of Blue Creek. The report also describes a potential water-quality monitoring program that would allow the determination of annual loads of selected chemical constituents entering Blue Creek from the mine basin and information about the type of ground-water tracers and procedures needed to examine flow paths near the retention pond

  18. Economic strain and perceptions of social cohesion in Europe: does institutional trust matter? / Rhys Andrews, Sebastian Jilke, Steven van de Walle

    Index Scriptorium Estoniae

    Andrews, Rhys

    2014-01-01

    Artikkel analüüsib, kuidas eurooplased tajuvad sotsiaalset ühtekuuluvust, võttes sealjuures arvesse majandussurvet ja institutsionaalset usaldust. Aluseks on Eurobaromeetri uuring vaesusest ja sotsiaalsest tõrjutusest (2010), mis haaras 27 liikmesriiki (sh Eesti)

  19. Stevens Institute SYS-625 Final Paper: Busy Parents Need Extremely Fast, Quality Home-Cooked Dinners That Their Kids Will Eat

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, Carol A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-01-30

    This study provides a modern take on an age-old need: busy parents need extremely fast, high quality home-cooked dinners that their kids will eat. In the past decade, the number of choices that parents have for filling this need have proliferated, largely due to technological advances. Our study proposes to leverage this technology in building a system geared toward decreasing whining in kids and increasing the sanity of their parents.

  20. 75 FR 10793 - FY2010 Supplemental Funding for Brownfields Revolving Loan Fund (RLF) Grantees

    Science.gov (United States)

    2010-03-09

    ... (213) 244- 1850. EPA Region 10, Susan Morales, AK, ID, OR, WA 1200 Sixth Avenue, Suite Morales.Susan...: March 2, 2010. David R. Lloyd, Director, Office of Brownfields and Land Revitalization, Office of Solid...

  1. 76 FR 6087 - Draft Weapons Safety Assessment on the Use of Enhanced Weapons; Notice of Availability and...

    Science.gov (United States)

    2011-02-03

    ...: 301-415-6557; e-mail: [email protected] ; or Susan Bagley, Office of Nuclear Security and Incident...: Susan.Bagley@nrc.gov . SUPPLEMENTARY INFORMATION: On August 8, 2005, President Bush signed into law the...

  2. Effects of cueing and collaboration on the Acquisition of Complex Legal Skills

    NARCIS (Netherlands)

    Hummel, Hans; Paas, Fred; Koper, Rob

    2005-01-01

    Hummel, H. G. K., Paas, F., & Koper, R. (2006). Effects of cueing and collaboration on the Acquisition of Complex Legal Skills. British Journal of Educational Psychology, 76(3), 613-632. [Also availabe at http://hdl.handle.net/1820/1646

  3. Effects of cueing and collaboration on the Acquisition of Complex Legal Skills

    NARCIS (Netherlands)

    Hummel, Hans; Paas, Fred; Koper, Rob

    2008-01-01

    Hummel, H. G. K., Paas, F., & Koper, R. (2006). Effects of cueing and collaboration on the Acquisition of Complex Legal Skills. British Journal of Educational Psychology, 76(3), 613-632. [Also availabe at http://hdl.handle.net/1820/482

  4. Report of the Results of an IMS LEarning Design Expert Workshop

    NARCIS (Netherlands)

    Neumann, Susanne; Klebl, Michael; Griffiths, David; Hernández-Leo, Davinia; De la Fuente-Valentin, Luis; Hummel, Hans; Brouns, Francis; Derntl, Michael; Oberhuemer, Petra

    2009-01-01

    Neumann, S., Klebl, M., Griffiths, D., Hernández-Leo, D., de la Fuente Valentín, L., Hummel, H., Brouns, F., Derntl, M., & Oberhuemer, P. (2010). Report of the Results of an IMS Learning Design Expert Workshop. International Journal Of Emerging Technologies In Learning (IJET), 5(1), pp.

  5. The role of place-based social learning [Chapter 7

    Science.gov (United States)

    Daniel R. Williams

    2017-01-01

    Hummel's observations on the limits of science to inform practice provides a useful starting point for a book chapter devoted to examining post-normal environmental policy where the "facts are uncertain, values in dispute, stakes high, and decisions urgent" (Funtowicz and Ravetz 1993, 739, 744). Central to the argument here is that the integration of...

  6. Rights through making : skills for pervasive ethics

    NARCIS (Netherlands)

    Trotto, A.

    2011-01-01

    This thesis starts with a Manifesto, bold, passionate and ambitious. Goals are set high, as to commit to a major endeavour: how can design contribute to a new civilisation. The first version was written in 2006 in Bertinoro, Italy, where Caroline Hummels, Kees Overbeeke and I were giving a workshop

  7. Potential of variable intake manifolds to reduce CO{sub 2} emissions in part load; Potenziale von Schaltsaugrohren zur CO{sub 2}-Reduktion in der Teillast

    Energy Technology Data Exchange (ETDEWEB)

    Buehl, Heinz; Pietrowski, Herbert [Mann + Hummel GmbH, Ludwigsburg (Germany). Intake Manifolds; Kratzsch, Matthias [IAV GmbH, Berlin (Germany). Fachbereich Ottomotorenentwicklung; Guenther, Michael [IAV GmbH, Chemnitz (Germany). Abt. Verbrennung/Thermodynamik Ottomotoren

    2013-11-01

    Since the introduction of turbochargers the use of variable intake manifolds to increase performance has declined. In addition to influencing the full load characteristics, variable intake manifolds, however, offer advantages in part load. In a joint project, Mann + Hummel and IAV have examined the fuel saving potential of variable intake manifolds with two current gasoline engine concepts in the NEDC. (orig.)

  8. Formation of nanoscale tungsten oxide structures and colouration ...

    Indian Academy of Sciences (India)

    The X-ray diffraction, together with transmission electron microscopic studies have revealed formation of regular polyhedral nanocrystalline ..... For molecular structure and orientation determination, the ... self-similarity within a complicated system. ..... Hummel R I 1997 Handbook of optical properties: Optics of small particles ...

  9. Design Guidelines for Collaboration and Participation with Examples from the LN4LD (Learning Network for Learning Design)

    NARCIS (Netherlands)

    Burgos, Daniel; Hummel, Hans; Tattersall, Colin; Brouns, Francis; Koper, Rob

    2007-01-01

    Burgos, D., Hummel, H. G. K., Tattersall, C., Brouns, F., & Koper, R. (2009). Design Guidelines for Collaboration and Participation with Examples from the LN4LD (Learning Network for Learning Design). In L. Lockyer, S. Bennett, S. Agostinho & B. Harper (Eds.), Handbook of Research on Learning Design

  10. A Computational Account of Children's Analogical Reasoning: Balancing Inhibitory Control in Working Memory and Relational Representation

    Science.gov (United States)

    Morrison, Robert G.; Doumas, Leonidas A. A.; Richland, Lindsey E.

    2011-01-01

    Theories accounting for the development of analogical reasoning tend to emphasize either the centrality of relational knowledge accretion or changes in information processing capability. Simulations in LISA (Hummel & Holyoak, 1997, 2003), a neurally inspired computer model of analogical reasoning, allow us to explore how these factors may…

  11. Scripted collaboration in serious gaming for complex learning: Effects of multiple perspectives when acquiring water management skills

    NARCIS (Netherlands)

    Hummel, Hans; Van Houcke, Jasper; Nadolski, Rob; Van der Hiele, Tony; Kurvers, Hub; Löhr, Ansje

    2010-01-01

    Hummel, H. G. K., Van Houcke, J., Nadolski, R. J., Van der Hiele, T., Kurvers, H., & Löhr, A. (2011). Scripted collaboration in gaming for complex learning: Effects of multiple perspectives when acquiring water management skills. British Journal of Educational Technology, 42(6),

  12. 75 FR 7043 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-16

    ... Valley, AL 01/25/10 01/15/10 Office (Comp). 73343 Convergys, IMG (Wkrs)...... Lake Mary, FL......... 01... Tardy-Conners Group, LLC Monson, ME 01/26/10 01/22/10 (Wkrs). 73360 Mann-Hummel Advanced Louisville, KY...

  13. Perfectionism: A Risk to Self-Harm

    Science.gov (United States)

    Cranab, A. Linsey; Raja, B. William Dharma

    2015-01-01

    Naturally humans strive to do their work. But when it exceeds a limit, it becomes neurotic and also not healthy perfectionism. Perfectionism is always not pleasurable, and people typically confuse their talents and capabilities with their perfectionism. In fact, perfectionism interferes with a person's ability to do well (Hummel, 2000). This paper…

  14. Recommendation strategies for e-learning: preliminary effects of a personal recommender system for lifelong learners

    NARCIS (Netherlands)

    Drachsler, Hendrik; Hummel, Hans; Van den Berg, Bert; Eshuis, Jannes; Berlanga, Adriana; Nadolski, Rob; Waterink, Wim; Boers, Nanda; Koper, Rob

    2007-01-01

    Drachsler, H., Hummel, H. G. K., Van den Berg, B., Eshuis, J., Berlanga, A. J., Nadolski, R. J., Waterink, W., Boers, N., & Koper, R. (2007). Recommendation strategies for e-learning: preliminary effects of personal recommender system for lifelong learners. Unpublished manuscript.

  15. Matter of transformation : designing an alternative tomorrow inspired by phenomenology

    NARCIS (Netherlands)

    Hummels, C.C.M.; Lévy, P.D.

    2013-01-01

    In this month’s cover story, Caroline Hummels and Pierre Lévy propose an alternative, value-based vision for design: Can we create alternative ways to engage with the world based on trusting our senses? Where intuition is as valuable as logic? Where commitment and engagement are valuable assets for

  16. ReMashed – Recommendation Approaches for Mash-Up Personal Learning Environments in Formal and Informal Learning Settings

    NARCIS (Netherlands)

    Drachsler, Hendrik; Pecceu, Dries; Arts, Tanja; Hutten, Edwin; Rutledge, Lloyd; Van Rosmalen, Peter; Hummel, Hans; Koper, Rob

    2009-01-01

    Drachsler, H., Peccau, D., Arts, T., Hutten, E., Rutledge, L., Van Rosmalen, P., Hummel, H. G. K., & Koper, R. (2009). ReMashed – Recommendation Approaches for Mash-Up Personal Learning Environments in Formal and Informal Learning Settings. Presentation at the 2nd Workshop Mash-Up Personal Learning

  17. ReMashed – Recommendation Approaches for Mash-Up Personal Learning Environments in Formal and Informal Learning Settings

    NARCIS (Netherlands)

    Drachsler, Hendrik; Pecceu, Dries; Arts, Tanja; Hutten, Edwin; Rutledge, Lloyd; Van Rosmalen, Peter; Hummel, Hans; Koper, Rob

    2009-01-01

    Drachsler, H., Peccau, D., Arts, T., Hutten, E., Rutledge, L., Van Rosmalen, P., Hummel, H. G. K., & Koper, R. (2009). ReMashed – Recommendation Approaches for Mash-Up Personal Learning Environments in Formal and Informal Learning Settings. In F. Wild, M. Kalz, M. Palmér & D. Müller (Eds.),

  18. Exploring Architectures for Fast and Easy Development of Immersive Learning Scenarios

    NARCIS (Netherlands)

    Nadolski, Rob; Slootmaker, Aad; Hummel, Hans

    2009-01-01

    Nadolski, R. J., Slootmaker, A., & Hummel, H. G. K. (2009). Exploring Architectures for Fast and Easy Development of Immersive Learning Scenarios. Presentation given at Online Educa. December, 3-4, 2009, Berlin, Germany. [For Powerpoint-version of this presentation. Please

  19. Fostering participation in learning networks by using reward systems and face-to-face meetings

    NARCIS (Netherlands)

    Hummel, Hans; Tattersall, Colin; Burgos, Daniel; Brouns, Francis; Koper, Rob

    2006-01-01

    Hummel, H. G. K., Tattersall, C., Burgos, D., Brouns, F. M. R., & Koper, E. J. R. (Submitted). Fostering participation in learning networks by using reward systems and face-to-face meetings. In Proceedings of ICALT 2006 Conference. July 5-7, Kerkrade, The Netherlands

  20. Evaluation of Navy Human Relations Training for Civilian and Military Supervisors and Managers - A Conceptual Framework and a Case Study

    Science.gov (United States)

    1977-05-20

    including: estimate of true gain score; a base-free measure of change obtained by removing Q ^Barbara Hummel-Rossi and Sharon L. Weinberg, "Practical...Commanding Officer 1 Psychological Research Unit Chancery House 485 Bourke Street Melbourne vie 3000 Austrailia Capt. Charles Baldwin Bureau of

  1. Interface design for digital courses

    NARCIS (Netherlands)

    Tabbers, Huib; Kester, Liesbeth; Hummel, Hans; Nadolski, Rob

    2005-01-01

    This text should be referred to as: Tabbers, H., Kester, L., Hummel, H. G. K., & Nadolski, R. J. (2003). Interface design for digital courses. In W. Jochems, J. van Merriënboer, & R. Koper (Eds). Integrated e-learning: implications for pedagogy, technology & organisation (pp. 100-111). London:

  2. The Impact of Discovering Life beyond Earth

    Science.gov (United States)

    Dick, Steven J.

    2016-01-01

    Introduction: astrobiology and society Steven J. Dick; Part I. Motivations and Approaches. How Do We Frame the Problems of Discovery and Impact?: Introduction; 1. Current approaches to finding life beyond earth, and what happens if we do Seth Shostak; 2. The philosophy of astrobiology: the Copernican and Darwinian presuppositions Iris Fry; 3. History, discovery, analogy: three approaches to the impact of discovering life beyond earth Steven J. Dick; 4. Silent impact: why the discovery of extraterrestrial life should be silent Clément Vidal; Part II. Transcending Anthropocentrism. How Do We Move beyond our Own Preconceptions of Life, Intelligence and Culture?: Introduction; 5. The landscape of life Dirk Schulze-Makuch; 6. The landscape of intelligence Lori Marino; 7. Universal biology: assessing universality from a single example Carlos Mariscal; 8. Equating culture, civilization, and moral development in imagining extraterrestrial intelligence: anthropocentric assumptions? John Traphagan; 9. Communicating with the other: infinity, geometry, and universal math and science Douglas Vakoch; Part III. Philosophical, Theological, and Moral Impact. How Do We Comprehend the Cultural Challenges Raised by Discovery?: Introduction; 10. Life, intelligence and the pursuit of value in cosmic evolution Mark Lupisella; 11. 'Klaatu barada nikto' - or, do they really think like us? Michael Ruse; 12. Alien minds Susan Schneider; 13. The moral subject of astrobiology: guideposts for exploring our ethical and political responsibilities towards extraterrestrial life Elspeth Wilson and Carol Cleland; 14. Astrobiology and theology Robin Lovin; 15. Would you baptize an extraterrestrial? Guy Consolmagno, SJ; Part IV. Practical Considerations: How Should Society Prepare for Discovery - and Non-Discovery?: Introduction; 16. Is there anything new about astrobiology and society? Jane Maienschein; 17. Evaluating preparedness for the discovery of extraterrestrial life: considering potential

  3. The role of coarse woody debris in southeastern pine forests; preliminary results from a large-scale experiment.

    Energy Technology Data Exchange (ETDEWEB)

    McCay Timothy, S.; Hanula, James, L.; Loeb, Susan, C.; Lohr, Steven, M.; McMinn, James, W.; Wright-Miley. Bret, D.

    2002-08-01

    McCay, Timothy S., James L. Hanula, Susan C. Loeb, Steven M. Lohr, James W. McMinn, and Bret D. Wright-Miley. 2002. The role of coarse woody debris in southeastern pine forests; preliminary results from a large-scale experiment. 135-144. In: Proceedings of the symposium on the ecology and management of dead wood in western forests. 1999 November 2-4; Reno, NV. Gen. Tech. Rep. PSW-GTR-181. Albany, CA: Pacific Southwest Research Station, Forest Service, U.S. Department of Agriculture 949 p. ABSTRACT: We initiated a long-term experiment involving manipulation of coarse woody debris (CWD) at the Savannah River National Environmental Research Park in the upper Coastal Plain of South Carolina. Each of four 9.3-ha plots in each of four blocks was subject to one of the following treatments: removal of all snags and fallen logs, removal of fallen logs only, felling and girdling to simulate a catastrophic pulse of CWD, and control. Removal treatments were applied in 1996, and the felling or snag-creation treatment will be applied in 2000-2001. Monitoring of invertebrate, herptile, avian, and mammalian assemblages and CWD dynamics began immediately after CWD removal and continues through the present. Removal treatments resulted in a fivefold to tenfold reduction in CWD abundance. To date, significant differences among treatments have only been detected for a few animal taxa. However, preliminary results underscore the benefits of large-scale experiments. This experiment allowed unambiguous tests of hypotheses regarding the effect of CWD abundance on fauna. Coupled with studies of habitat use and trophic interactions, the experimental approach may result in stronger inferences regarding the function of CWD than results obtained through natural history observation or uncontrolled correlative studies.

  4. Staffing an Academic Reference Desk with Librarians is not Cost-effective. A Review of: Ryan, Susan M. “Reference Transactions Analysis: The Cost-effectiveness of Staffing a Traditional Academic Reference Desk.” Journal of Academic Librarianship 34.5 (2008: 389-99.

    Directory of Open Access Journals (Sweden)

    Cari Merkley

    2009-06-01

    Full Text Available Objective – To determine whether it is cost effective to staff an academic reference desk with librarians through an examination of the types of reference questions being asked and the qualifications required to answer them.Design – Content analysis of reference transaction logs and activity-based costing for reference services based on quantitative data derived from the logs.Setting – Stetson University, a private institution in the United States with an FTE of approximately 2500.Subjects – 6959 phone, email, and in-person reference transactions logged at the reference desk by four full-time and two part-time librarians.Methods – This study repurposes data originally collected to determine the frequency with which librarians turned to online versus print sources when responding to questions at the reference desk. Librarians working at the Stetson University library reference desk recorded all reference queries received in person, by phone, or by email for a total of eight months between 2002 and 2006. Data collection took place in two month intervals in fall 2002, spring 2003, spring 2006, and fall 2006. Each question and the sources used to address it were logged by the librarian. Directional questions that were not related to the library’s collections and technical questions dealing with printer or copier mechanical problems were counted, but the specifics of these questions were not recorded. It was felt that these queries would not yield data relevant to the original research question on sources used as they “did not directly relate to an information need” (391. A total of 6959 questions were logged by librarians during the four collection periods. Questions were recorded for only 4431 transactions; the remaining 2528 queries related to printer/copier problems or non-library specific directions and were described as “direction and machine: non- informational” (394. The 4431 recorded questions were then divided into four categories derived by the researcher: look-up (a search for a known item, directional (library-specific orientation to the space and collections, technology (assistance with using library technology and electronic resources, and reference. The category of reference was further subdivided into eight additional categories: catalogue search, citation help, database help, “guide to correct databases,” “personal knowledge or referral,” “quick internet search,” research, and Serials Solutions (392. “Guide to correct databases” referred to advice on the appropriate database to answer a question and serials solutions included questions that could be answered using the Serials Solutions product, such as the availability of a particular journal or article in the collection (392. Questions were assigned to the single most appropriate category by the researcher. Question categories were then mapped to “suggested staffing levels” (396. This determination was made by the researcher, and no details were given as to how the decision was made for each category. The three levels of staffing discussed were librarian, “trained student or staff,” and “well-trained staff/occasional librarian referral” (396. The cost of staffing the reference desk during the eight months captured in this study was calculated by multiplying the hours worked by each librarian by his/her individual average rate of pay across the four data collection periods. Indirect staff costs such as benefits were not included in this calculation. The average cost per reference transaction was determined by dividing the total salary costs by the total number of reference queries during the periods of study. Costs for those categories of questions best addressed by a librarian could then be determined. The actual number of librarians who participated in the study is unclear. The methodology refers to four full-time and two part-time librarians (391. However, later in the article there is reference to five full-time and three part-time librarians rather than the numbers initially stated (396. This may reflect staffing changes during the study period, with the first set of numbers referring to positions rather than individuals, but this cannot be verified with the evidence presented in the article.Main Results – It was determined that most questions asked at the reference desk during the study period could have been addressed by trained student and staff member rather than librarians. Only 11% (784 of questions logged were deemed sufficiently complex by the researcher to require the attention of a librarian. The remaining 6175 transactions (89% of all those logged could most likely be handled by a different staffing complement. According to Ryan, approximately 74% of the reference transactions, including directional, technology, “quick internet,” and known item searching questions could have been answered by “trained student and staff” (396. Questions on catalogue searching, databases, citations, Serial Solutions, and personal knowledge/referrals, representing approximately 15% of all questions, could have been handled by experienced and knowledgeable staff with limited librarian intervention. The complexity of the question was in part judged by the number of sources required to answer it, with most (75% answerable with just one source. The total cost of staffing the reference desk with librarians for the eight months studied was approximately US$49,328.00. A total of 6959 questions were logged during this period, resulting in an average cost of US$7.09 per reference transaction. This cost is approximate, as the exact time spent on each question was not recorded. The cost of answering “non-informational” directional and technical questions was the most significant (396. This category represented 36.3% of all questions received at the reference desk, with a total staffing cost of $17, 919.41 ($7.09 x 2528. “Information-orientated” directional and technology questions followed at 15.4% (US$7,620 and 12.4% (US$6,110.18 respectively (396. According to Ryan, questions in all three categories could be addressed by students and staff. The cost of addressing research questions, the only category requiring librarians, was US$5557.29. Research transactions were greatly outnumbered by directional and technology related questions. An average of 3.6 research questions were asked at the reference desk during the 12 hours it was open each day, compared to 20.8 directional/technical questions.Conclusion – The nature of questions logged at the Stetson University library reference desk suggests that it is inefficient to staff the desk with librarians, given the salary costs of such a staffing model and the fact that librarian’s skills may not be required to answer most of the questions posed. Since the number of questions that need a librarian is so low, Ryan suggests that alternative staffing and service models be considered, so the energies of librarians could be more effectively employed elsewhere in the organization in areas such as information literacy instruction and the development of enhanced web services. It is noted that any reorganization of reference services should be done in concert with user surveys, consultation with staff, and extensive training to prepare staff for new roles. Suggested areas for further research identified by the researcher include the quality of reference transactions in an increasingly online environment.

  5. Online Programs and Geographic Proximity are Key Determinants of Information Professionals’ Interest in Pursuing Post-Master’s Education at the Doctoral Level. A Review of: Powell, Ronald R. and Susan E. Boling. “Post-Master’s Educational Needs of Information Professionals.” Journal of Access Services 3.4 (2005: 29-43.

    Directory of Open Access Journals (Sweden)

    Martha Ingrid Preddie

    2009-03-01

    Full Text Available Objective – To investigate post-master’s educational needs and interests of information professionals.Design – Survey research using print and electronic questionnaires.Setting – The geographic area surrounding Wayne State University in Michigan, United States of America.Subjects – Members of the library associations of Michigan, Ohio, Indiana, and Southwestern Ontario, Canada.Methods – Systematic random samples were derived from the membership lists of the library associations in Ohio, Indiana, and Southwestern Ontario. Paper questionnaires were mailed to those selected. Michigan Library Association’s official policy barred the release of its membership list to researchers. Consequently, announcements of the survey were placed in three successive issues of the Association’s electronic newsletter. Interested members were directed to a website to complete an electronic version of the questionnaire. This option was also extended to members of the other three library associations. The overall research question was investigated through specific questions that sought to ascertain the overall level of interest in professional library and information studies (LIS education, levels of interest in specific types of programs, factors that favoured or deterred enrolment in doctoral programs, as well as the fields of study that were preferred for combination with LIS in doctoral programs. With the exception of demographic type questions (e.g., place of residence and educational qualifications and two questions that required open ended responses, the questionnaire design encompassed questions with Likert scale type responses. Analysis of the responses included descriptive statistics, the use of Pearson chi square to determine statistically significant relationships, and, to a lesser extent, content analysis.Main Results – A total of 270 questionnaires(33% were returned from three populations: Ohio, Indiana, and Ontario. A self-selected sample of 101 members (6% of the Michigan Library Association responded. In general, almost 80% of the respondents admitted some importance to adding to their LIS qualification. However, only 41% felt that this was important or extremely important. From a choice of six educational offerings, namely, continuing education activities, non-degree master’s coursework, a second master’s degree, post-master’s certification, doctoral programs, and other, continuing education activities was the most valued, by 65.5% of the respondents. Participants were asked about their reasons, and the importance of these, for considering or deciding to enrol in an LIS doctoral program. The yearning to acquire knowledge was reported by 69.7% as the major reason, followed by 45.8% of the respondents who cited the wish to increase their income potential. In terms of major factors, prestige received the lowest rating, 21.1%. The time involved (73.8%, cost(66.3%, and distance from the program (63.2% were cited as the major deterrents to enrolling in doctoral programs. When asked about the likelihood of pursuing a doctoral LIS program in combination with business administration, computer science, or without any combination, “not likely” was the most popular choice. Those who were very likely or likely to pursue a joint program totalled approximately 30% of the respondents, while 37% indicated an interest in undertaking a doctorate in LIS only. The most frequent reasons proffered by those who selected “not likely” or “definitely not” for any of the three doctoral offerings included lack of interest, mitigating factors (e.g. time, cost, age, and program location, unfavourable cost/benefit analysis, preference for another area of knowledge,and the view that Ph.D.s were only useful for university faculty. Given the option to name subject areas that they desired to see combined with LIS in a doctoral program, 23 of 101 respondents proposed education, while 19 opted for public administration. A question inviting any other comments on the issue of post-master’s education yielded a predominant desire for “non traditional instruction,” particularly online courses as well as classes held in convenient locations. In terms of relationships between geographic location and factors that influenced interest in enrolling in a doctoral program, the desire “to become a more effective manager,” and “other” were statistically significant. The analysis also revealed a strong positive relationship between willingness to pursue an LIS-only doctoral program and the availability of such a program in geographic proximity. Similarly, there was a strong relationship between willingness to pursue an LIS program in close vicinity and the importance that was given to further LIS education.Conclusion – Online instruction and geographic proximity are key determinants of information professionals’ interest in pursuing post-master’s education at the doctoral level. Continuing education activities, non-degree coursework, and certificate programs are preferred over doctoral LIS programs, despite the finding that the major reason for enrolling in doctoral LIS programs is to fulfill the desire for knowledge acquisition. Schools offering Library and Information Science studies need to explore options for providing distance-education doctoral LIS programs as a means of reversing the current shortage of LIS faculty.

  6. Human Resource Management, 11th Edition International Student Version. By David A. DeCenzo, Stephen P. Robbins and Susan L. Verhulst, Wiley, 2013; 448 Pages. Price £54.99 / €66.00, ISBN 978-1-1183-7971-4

    OpenAIRE

    Shu-Kun Lin

    2013-01-01

    The 11th Edition of Human Resource Management helps students understand and remember concepts through a straightforward and conversational writing style and a wealth of examples to clarify ideas and build interest. The authors provide a strong foundation of essential elements of Human Resource Management (HRM) as well as a clear understanding of how Human Resource Management links with business strategy. Through practical applications, the authors illustrate the importance of employees on eve...

  7. Human Resource Management, 11th Edition International Student Version. By David A. DeCenzo, Stephen P. Robbins and Susan L. Verhulst, Wiley, 2013; 448 Pages. Price £54.99 / €66.00, ISBN 978-1-1183-7971-4

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin

    2013-02-01

    Full Text Available The 11th Edition of Human Resource Management helps students understand and remember concepts through a straightforward and conversational writing style and a wealth of examples to clarify ideas and build interest. The authors provide a strong foundation of essential elements of Human Resource Management (HRM as well as a clear understanding of how Human Resource Management links with business strategy. Through practical applications, the authors illustrate the importance of employees on every level of the organization, helping students understand HRM elements such as recruitment, training, motivation, retention, safety, the legal environment, and how they support successful business strategies.

  8. Response to the Colloquium "The Organisation for Economic Co-Operation and Development's International Early Learning Study: Opening for Debate and Contestation", by Peter Moss, Gunilla Dahlberg, Susan Grieshaber, Susanna Mantovani, Helen May, Alan Pence, Sylvie Rayna, Beth Blue Swadener and Michel Vandenbroeck, "Contemporary Issues in Early Childhood" 17(3)

    Science.gov (United States)

    Mackey, Glynne; Hill, Diti; De Vocht, Lia

    2016-01-01

    In this article, the authors opine that the introduction of an international assessment of children's early learning, such as proposed by the OECD with its planned International Early Learning Study, will shift the emphasis away from pedagogies which focus on that which is meaningful and relevant in children's lives and their learning, to an…

  9. The Need for a Revised Joint Personnel Accounting Doctrine

    Science.gov (United States)

    2011-05-22

    recoveries to field operations for the 11 David R. Graham, Ashley N. Bybee , Susan L. Clark-Sestak, and...Naval War College, 2009), XI-43. 16 David R. Graham, Ashley N. Bybee , Susan L. Clark-Sestak, and Michal S. Finnin, Assessment of DOD Central...Division, 8 June 2005. Graham, David R., Ashley N. Bybee , Susan L. Clark-Sestak, and Michal S. Finnin. Assessment of DOD Central

  10. Process Challenges in Compound Semiconductors.

    Science.gov (United States)

    1988-08-01

    dimension in GaAs quantum well wires and boxes. Appl. Phys. Lett. 49:1275. Cox, H. M., S. G. Hummel, and V. G. Keramidas. 1986. Vapor levitation epitaxy...improved materials, and new device concepts. Many of these involve the fabrication of multilayer structures for quantum well lasers and detectors...dimensions, where quantum effects dominate, has already led to a number of conceptual breakthroughs for new devices and circuits. Such breakthroughs are

  11. 78 FR 29200 - Advisory Committee for the Study of Eastern Europe and the Independent States of the Former...

    Science.gov (United States)

    2013-05-17

    ... advanced graduate training, language training, and postdoctoral research. The committee includes...: April 19, 2013. Susan H. Nelson, Executive Director, Advisory Committee for Study of Eastern Europe and...

  12. 76 FR 65500 - Fisheries of the Exclusive Economic Zone Off Alaska; Recordkeeping and Reporting Requirements...

    Science.gov (United States)

    2011-10-21

    .../seattlelakeunion/location.php . FOR FURTHER INFORMATION CONTACT: Susan Hall, 907-586-7462. SUPPLEMENTARY... workshops will be physically accessible to people with disabilities. Requests for sign language...

  13. 77 FR 24491 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-04-24

    ... Smyrna, Tennessee; James A. Campbell, Nashville, Tennessee; William Kent Coleman, Murfreesboro, Tennessee... River Hills, Wisconsin; David J. Lubar, Fox Point, Wisconsin; Susan Lubar Solvang, and Joan P. Lubar...

  14. 50 CFR 697.25 - Adjustment to management measures.

    Science.gov (United States)

    2010-10-01

    ... of the Magnuson-Stevens Act, or to meet overfishing and rebuilding requirements of the Magnuson... consistent with the national standards of the Magnuson-Stevens Act, or to meet overfishing and rebuilding...

  15. 76 FR 57712 - Performance Review Board Membership

    Science.gov (United States)

    2011-09-16

    ... DEPARTMENT OF COMMERCE Performance Review Board Membership AGENCY: Economics and Statistics... the Performance Review Board (PRB) in accordance with the Economics and Statistics Administration's.... Bostic, Jr., Arnold A. Jackson, Theodore A. Johnson, Steven J. Jost, J. Steven Landefeld, Jennifer Madans...

  16. Cost Recovery Data Set

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Magnuson-Stevens Fishery Conservation and Management Act (Magnuson-Stevens Act) requires NOAA’s National Marine Fisheries Service (NMFS) to collect fees to...

  17. Legitimating clinical research in the study of organizational culture

    OpenAIRE

    Schein, Edgar H.

    1991-01-01

    "Adapted from the text of the Sixteenth Annual Frederick J. Gaudet Lecture, sponsored by the Stevens Chapter of Psi Chi, The National Honor Society in Psychology, Stevens Institute, Hoboken, N.J., April 30, 1991"--P. 1.

  18. 78 FR 8547 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2013-02-06

    ... Prickett (NHGRI), and Steven Rosenberg (NCI). Publication: Prickett TD, et al. Exon capture analysis of G... Steven Rosenberg (NCI) Publication: Prickett TD, et al. Exon capture analysis of G-protein coupled... Steven Rosenberg (NCI) Publication: Cronin JC, et al. Frequent mutations in the MITF pathway in melanoma...

  19. 77 FR 40073 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2012-07-06

    ... Immunotherapy. For collaboration opportunities, please contact Steven A. Rosenberg, M.D., Ph.D. at [email protected], Richard A. Morgan, Steven A. Rosenberg (all of NCI). Intellectual Property: HHS Reference No. E-105-2012/0... contact Steven A. Rosenberg, M.D., Ph.D. at [email protected] . Antagonists of Hyaluronan Signaling for...

  20. Mission Engineering Competencies Technical Report

    Science.gov (United States)

    2018-04-30

    technology has changed history , Apollo lunar program made a staggering contribution to high tech development. Report No. SERC-2018-TR-106...Gregg Vesonder, Stevens Institute of Technology Co-Principal Investigator: Dr. Dinesh Verma, Stevens Institute of Technology Research Team...Stevens Institute of Technology : Dr. Nicole Hutchison, Mr. Sergio Luna, Mr. William Miller, Dr. Hoong Yan See Tao, Dr. Jon

  1. Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects

    NARCIS (Netherlands)

    Peter T. Theunissen; Bruce Beyer; Sonia Beken

    2016-01-01

    And co-authors William J. Breslin, Gregg D. Cappon, Connie L. Chen, Gary Chmielewski, Luc de Schaepdrijver, Brian Enright, Jennifer E. Foreman, Wafa Harrouk, Kok-Wah Hew, Alan M. Hoberman, Julia Y. Hui, Thomas B. Knudsen, Susan B. Laffan, Susan L. Makris, Matthew Martin, Mary Ellen McNerney,

  2. Big Data for Education: Data Mining, Data Analytics, and Web Dashboards. Governance Studies at Brookings

    Science.gov (United States)

    West, Darrell M.

    2012-01-01

    Twelve-year-old Susan took a course designed to improve her reading skills. She read short stories and the teacher would give her and her fellow students a written test every other week measuring vocabulary and reading comprehension. A few days later, Susan's instructor graded the paper and returned her exam. The test showed that she did well on…

  3. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. SEBA SUSAN. Articles written in Sadhana. Volume 41 Issue 12 December 2016 pp 1393-1406. Image coding based on maximum entropy partitioning for identifying improbable intensities related to facial expressions · SEBA SUSAN NANDINI AGGARWAL SHEFALI CHAND AYUSH GUPTA.

  4. 78 FR 16472 - Deposit of Biological Materials

    Science.gov (United States)

    2013-03-15

    ... comment'' in the subject line of the message. Mail: Susan K. Fawcett, Records Officer, Office of the Chief... by FedEx ``Domestic Overnight'' is estimated to be $75. If the shipment requires pick-up by FedEx... responses. Dated: March 12, 2013. Susan K. Fawcett, Records Officer, USPTO, Office of the Chief Information...

  5. 77 FR 31719 - Grading and Inspection, General Specifications for Approved Plants and Standards for Grades of...

    Science.gov (United States)

    2012-05-30

    .... DATES: Effective: June 29, 2012. FOR FURTHER INFORMATION CONTACT: Susan Sausville, Chief, Standardization Branch, Dairy Programs, AMS, USDA, telephone (202) 720- 9382 or email Susan[email protected] before being picked up; however, if the person making the test is unable to get to the farm before the...

  6. Army Cyber Mission Force - Ambitions and Realities

    Science.gov (United States)

    2015-05-21

    London: A & C Black, 2006), 219. 3 Ibid., 227. 4 Susan Pines, Veda Dickerson, and Lori Cates, eds., O*NET Dictionary of Occupational Titles, 2nd ed...Pines, Susan, Veda Dickerson, and Lori Cates. "Experience." In O*NET Dictionary of Occupational Titles

  7. A Comparison of HAART Outcomes between the US Military HIV Natural History Study (NHS) and HIV Atlanta Veterans Affairs Cohort Study (HAVACS)

    Science.gov (United States)

    2013-05-01

    Acknowledgments The IDCRP HIV Working Group includes: Susan Banks, RN, CAPT Mary Bavaro, MD, Ionut Bebu, PhD, Helen Chun, MD, Nancy Crum- Cianflone, MD, MPH...Cathy Decker, MD, Conner Eggleston, LTC Tomas Ferguson, MD, COL Susan Fraser, MD, MAJ Joshua Hartzell, MD, MAJ Joshua Hawley, MD, LTC Gunther Hsue, MD

  8. 76 FR 77206 - Citric Acid and Certain Citrate Salts From the People's Republic of China: Final Results of...

    Science.gov (United States)

    2011-12-12

    ... Memorandum to Susan H. Kuhbach, Office Director, AD/CVD Operations, Office 1, from David Layton..., 2011. \\3\\ See Memorandum to Susan H. Kuhbach, Office Director, AD/CVD Operations, Office 1, from Austin... provision of sulfuric acid for less than adequate remuneration (``LTAR'') for both RZBC and Yixing, and...

  9. 04 Brittan pp 55-77

    African Journals Online (AJOL)

    Tienie

    Brink claims that censorship turns the writer into a “physio- logist” who must ..... her personal awakening in terms that may remind us of Susan du Toit. Like Susan, she is ... language. Once the image of Ben and Melanie is captured on film, it.

  10. The Development of the C3 Framework

    Science.gov (United States)

    Social Education, 2013

    2013-01-01

    Susan Griffin, executive director of NCSS, was chair of the Task Force of Professional Organizations that initiated and guided the development of "The College, Career, and Civic Life (C3) Framework for Social Studies State Standards", which will soon be released. In this interview with "Social Education", Susan explains how the…

  11. A 9-Year-Old Girl Discovers That Her Mother Was Murdered.

    Science.gov (United States)

    Schonfeld, David J; Shekunov, Julia; Jellinek, Michael; Stein, Martin T

    Susan was a 9-year-old girl living with her mother; she had never met her father. Her mother returned one evening from her job as a cocktail waitress and Susan met her at the apartment door to let her know they had run out of cat food. Her mother said she would go and buy some the next morning because it was late and she was tired, but Susan insisted she go out that evening because the cat had not eaten all day. Her mother was fatally shot in the parking lot of the convenience store shortly thereafter; since there was no robbery involved, the police suspected it was someone that she knew. Susan's extended family had her move out of the apartment that evening and relocate to live with her aunt and uncle out-of-state. The transition happened quickly. Susan was unable to return to her apartment to pick up any additional belongings and never returned to say goodbye to her friends. The family decided she was too young to attend the funeral.Susan had trouble fitting in with her aunt and uncle's family; they had 2 children who were 8 and 6 years old, and Susan felt she was being treated like a baby. She resented having a bedtime (her mother allowed her to stay up as late as she wished), and she complained that the work at school was boring and her classmates were childish. When the family went to a festival in town, she left abruptly without telling them, which frightened Susan's aunt and uncle. They wanted to be supportive but felt that she needed more structure than her mother had provided her. Susan's aunt and uncle sought bereavement support for Susan from her pediatrician and parenting advice for themselves.

  12. Proceedings of Patient Reported Outcome Measure’s (PROMs Conference Sheffield 2016: advances in patient reported outcomes research

    Directory of Open Access Journals (Sweden)

    Tim Croudace

    2016-10-01

    Full Text Available Table of contents S1 Using computerized adaptive testing Tim Croudace S2 Well-being: what is it, how does it compare to health and what are the implications of using it to inform health policy John Brazier O1 “Am I going to get better?”—Using PROMs to inform patients about the likely benefit of surgery Nils Gutacker, Andrew Street O2 Identifying Patient Reported Outcome Measures for an electronic Personal Health Record Dan Robotham, Samantha Waterman, Diana Rose, Safarina Satkunanathan, Til Wykes O3 Examining the change process over time qualitatively: transformative learning and response shift Nasrin Nasr, Pamela Enderby O4 Developing a PROM to evaluate self-management in diabetes (HASMID: giving patients a voice Jill Carlton, Donna Rowen, Jackie Elliott, John Brazier, Katherine Stevens, Hasan Basarir, Alex Labeit O5 Development of the Primary Care Outcomes Questionnaire (PCOQ Mairead Murphy, Sandra Hollinghurst, Chris Salisbury O6 Developing the PKEX score- a multimodal assessment tool for patients with shoulder problems Dominic Marley, James Wilson, Amy Barrat, Bibhas Roy O7 Applying multiple imputation to multi-item patient reported outcome measures: advantages and disadvantages of imputing at the item, sub-scale or score level Ines Rombach, Órlaith Burke, Crispin Jenkinson, Alastair Gray, Oliver Rivero-Arias O8 Integrating Patient Reported Outcome Measures (PROMs into routine primary care for patients with multimorbidity: a feasibility study Ian Porter, Jaheeda Gangannagaripalli, Charlotte Bramwell, Jose M. Valderas O9 eRAPID: electronic self-report and management of adverse-events for pelvic radiotherapy (RT patients Patricia Holch, Susan Davidson, Jacki Routledge, Ann Henry, Kevin Franks, Alex Gilbert, Kate Absolom & Galina Velikova O10 Patient reported outcomes (PROMs based recommendation in clinical guidance for the management of chronic conditions in the United Kingdom Ian Porter, Jose M.Valderas O11 Cross-sectional and

  13. Assessment of DoD’s Central Identification Lab and the Feasibility of Increasing Identification Rates

    Science.gov (United States)

    2009-06-01

    Lab and the Feasibility of Increasing Identification Rates David R. Graham Ashley N. Bybee Susan L. Clark-Sestak Michael S. Finnin Approved for public...Feasibility of Increasing Identification Rates David R. Graham Ashley N. Bybee Susan L. Clark-Sestak Michael S. Finnin iii PREFACE This study was...6 . A U TH O R ( S ) 5 d . P R O JE C T N O. David R. Graham, Ashley N. Bybee , Susan L. Clark-Sestak, Michael S. Finnin 5 e . TAS K N O

  14. Glycolipids from the red alga Chondria armata (Kutz.) Okamura

    Digital Repository Service at National Institute of Oceanography (India)

    Al-Fadhli, A.; Wahidullah, S.; DeSouza, L.

    -309. van Hummel H.C. (1975) Chemistry and biosynthesis of plant galactolipids. Fortschr. Chem. Org. Naturst., 32, 267-95. Waugh, R.J., Murphy, R.C. (1996) Mass spectrometric analysis of four regioisomers of F2- isoprostanes formed by free radical... diagnostically important daughter ions at m/z 481, 735 and 761. The ions at m/z 735 and 761 reflect the neutral losses of the sn-1 and sn-2 substituent as free C18:1 and C16:0 carboxylic acid respectively supporting the presence of palmitic and oleic acyl...

  15. TROPHIC RELATIONS OF LADY BEETLES (COLEOPTERA, COCCINELLIDAE OF THE URALS

    Directory of Open Access Journals (Sweden)

    Z. I. Tyumaseva

    2016-05-01

    Full Text Available The article contains the study of the trophic relations of the lady beetles living in the Urals. The study allocates three ecological groups depending on the peculiarities of the beetles and larvae nutrition: phytophages, micetophages, and entomophages-predators. We have revealed 66 species of lady birds-predators and two species-phytophages: Subcoccinella vigintiquatuorpunctata (Linnaeus, 1758 and Bulaea lichatschovii (Hummel, 1827. In the group of obligatory micetophages in the Urals we registered the representatives of the tribe Halyziini, it is Halyzia sedecimguttata (Linnaeus, 1758 and Psyllobora vigintiduopunctata (Linnaeus, 1758.

  16. Proceedings of the SDIO/ONR Pulse Power Meeting (4th) Held in Los Angeles, California on June 20-21, 1991

    Science.gov (United States)

    1991-06-01

    H. Zhao, S.G. Hummel, J.S. Osinski, P.D. Dapkus, H. R. Fetterman , C. W. Myles, and M. A. Gundersen ........... 71 10. Experimental verification of a...member of the technical staff at Ar.e Rosen and Paul Stabile of David Sarnoff Research Center Sandia National Laboratories (SNL), Albuquerque, New...choose a wave- p-i-n diode(6 ) provided by A. Rosen at the length with the photon energy greater than David Sarnoff Research Center. The p-i-n the

  17. 75 FR 36356 - Announcement of Changes to the Membership of the Performance Review Board

    Science.gov (United States)

    2010-06-25

    ..., ITA (new). 4. Edward C. Yang, Senior Director, China Non-Market Economy Compliance Unit, ITA. 5. Joel... Management, OS. Dated: June 18, 2010. Susan Boggs, Director, Office of Staffing, Recruitment and...

  18. 78 FR 19716 - International Consortium of Cardiovascular Registries

    Science.gov (United States)

    2013-04-02

    ... employees) is through Building 1 where routine security check procedures will be performed. For parking and... Internet access should contact Susan Monahan to register ( [email protected] or 301-796-5661...

  19. Sexual Health Concerns in Patients with Cardiovascular Disease

    Science.gov (United States)

    ... Patient Page Sexual Health Concerns in Patients With Cardiovascular Disease Lindsey Rosman , John M. Cahill , Susan L. McCammon , ... and difficulty achieving and maintaining an erection. 2 Cardiovascular disease and its treatment may also affect a man’s ...

  20. Resistance ja Rootsi turvaühiskond / Peeter Linnap

    Index Scriptorium Estoniae

    Linnap, Peeter, 1960-

    2001-01-01

    "Vastupanukunsti" näitus "The Path of Resistance : MoMa meets Moderna" Stockholmi Moodsa Kunsti Muuseumis, kuraatorid Susan Kismaric ja Joshua Siegel. Resistance'i kunsti raames käsitletakse ka nn. poliitilist kunsti

  1. Air Force Follow-On Review. Protecting The Force: Lessons From Fort Hood

    Science.gov (United States)

    2010-01-01

    Demorah Hayes Mrs. Sherry Terrell Ms. Jeanne Shamburger Mr. Andrew Thayer Graphic Designers Mr. Daniel Armstrong Ms. Susan Fair Printing Specialists Ms. Ann Bailey Mrs. Nedra Looney Mrs. Vivian O’Neal

  2. 78 FR 16675 - First Technology Transitions; Policy Task Force Workshop

    Science.gov (United States)

    2013-03-18

    ..., please submit name and company affiliation ahead of time by sending an email to susan[email protected] allow time to go through our security process. Lunch: Attendees may pre-order lunch, to be picked up by...

  3. Is Children's Programming Improving?

    Science.gov (United States)

    Potter, Rosemary Lee

    1979-01-01

    Susan Futterman, a former teacher and early childhood specialist for Action for Children's Television, comments on changing formats for children's programs, as well as on the role of educators in using television as a learning vehicle. (Editor/KC)

  4. 75 FR 15457 - Aquatic Nuisance Species Task Force Meeting

    Science.gov (United States)

    2010-03-29

    ...: http://anstaskforce.gov/meetings.php . FOR FURTHER INFORMATION CONTACT: Susan Mangin, Executive... on the ANS Task Force Web site at: http://anstaskforce.gov/meetings.php . Dated: March 19, 2010...

  5. 77 FR 61019 - Aquatic Nuisance Species Task Force Meeting

    Science.gov (United States)

    2012-10-05

    ...: http://anstaskforce.gov/meetings.php . FOR FURTHER INFORMATION CONTACT: Susan Mangin, Executive... information are on the ANS Task Force Web site at: http://anstaskforce.gov/meetings.php . Accessibility...

  6. 76 FR 15334 - Aquatic Nuisance Species Task Force Meeting

    Science.gov (United States)

    2011-03-21

    ... Task Force Web site at: http://anstaskforce.gov/meetings.php . FOR FURTHER INFORMATION CONTACT: Susan...: http://anstaskforce.gov/meetings.php . Dated: March 14, 2011. Jeffrey Underwood, Acting Assistant...

  7. 76 FR 21741 - Emergency Access Advisory Committee; Announcement of Establishment, and of Members and Co...

    Science.gov (United States)

    2011-04-18

    ... Gallaudet University--Norman Williams Hearing, Speech & Deafness Center--Donna Platt Intrado, Inc.--John... Communications--Kevin Green, alternate Susan Sherwood Vonage Holding Corp.--Brendan Kasper Washington Parish, LA...

  8. Governing how we care: contesting community and defining difference in U.S. public health programs

    National Research Council Canada - National Science Library

    Shaw, Susan J., Dr

    2012-01-01

    .... In Governing How We Care, medical anthropologist Susan Shaw examines the relationship between government and citizens using case studies of needle exchange and Welfare-to-Work programs to illustrate...

  9. 78 FR 57675 - Notice of Passenger Facility Charge Approvals and Disapprovals

    Science.gov (United States)

    2013-09-19

    ... efficient off-road vehicle. DETERMINATION: Disapproved. Each project was determined to not meet the... credits. DECISION DATE: March 20, 2013. FOR FURTHER INFORMATION CONTACT: Susan Moore, Orlando Airports...

  10. Kui sulg ei jookse... / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2003-01-01

    Kuidas stsenarist Charlie Kaufman kirjutas stsenaariumi oma loomevaevadest Susan Orleani raamatu filmiks kirjutamisel : mängufilm "Kuidas kirjutada kassafilmi" ("Adaptation") : režissöör Spike Jonze : Ameerika Ühendriigid 2002

  11. 76 FR 2905 - FY2011 Supplemental Funding for Brownfields Revolving Loan Fund (RLF) Grantees

    Science.gov (United States)

    2011-01-18

    ...- 3364, Fax (415) 972- 3364. EPA Region 10, Susan Morales, AK, ID, OR, WA... 1200 Sixth Avenue, Morales.... Dated: January 10, 2011. David R. Lloyd, Director, Office of Brownfields and Land Revitalization, Office...

  12. Kui kapital veab alt, siis turvaliselt / Aleksander Tsapov

    Index Scriptorium Estoniae

    Tsapov, Aleksander

    2006-01-01

    Kuraatorinäitus "Kapital (see veab meid alt)" Tallinna Kunstihoones. Kuraator Simon Sheikh. Fia-Stina Sandlundi, Katya Sanderi, Oliver Ressleri, Ashley Hunti ja Susan Kelly&Stephen Mortoni töödest näitusel

  13. 75 FR 59209 - Certain Coated Paper Suitable for High-Quality Print Graphics Using Sheet-Fed Presses from...

    Science.gov (United States)

    2010-09-27

    .... Lorentzen, Deputy Assistant Secretary for Import Administration, from Susan Kuhbach, Director, Office 1.... Provision of Standing Timber for Less Than Adequate Remuneration 2. Government Prohibition of Log Exports 3...

  14. 75 FR 46938 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-08-04

    ... Logistics LLC (NVO), 120 S. Woodland Blvd., 216, DeLand, FL 32720, Officers: Dietmar Lutte, Manager Member, (Qualifying Individual), Susan Lutte, Member, Application Type: New NVO License. Bridgeline Logistics..., (Qualifying Individual), Application Type: New OFF License. [[Page 46939

  15. 77 FR 75143 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-12-19

    ... the Year, Excellence in Promoting Cultural and Ethnic Diversity (in honor of Secretary Ronald Brown), Excellence in Business Leadership, and the Susan Snow Cotter Award for Excellence in Ocean and Coastal...

  16. 1. IV avati Tallinna Kunstihoone galeriis šoti videokunstinäitus "Nähtamatud väljad"

    Index Scriptorium Estoniae

    2004-01-01

    Kuraatorid Sarah Felton ja Su Grierson, osalevad kunstnikud Victoria Clare Bernie, Samantha Clark, Maria Doyle, S. Felton, S. Grierson, Belinda Guidi, Anne Bjerge Hansen, Metacorpus, Jane McInally, Rosalind Nashashibi, Susannah Silver ja Susan Sloan

  17. Raamatututvustus / Rein Põder

    Index Scriptorium Estoniae

    Põder, Rein, 1943-

    1995-01-01

    Rousseau, Jean-Jacques. Üksildase uitaja mõtisklused; Hill, Susan. Proua de Winter; Kõrvemaast põhjarannani : Kuusalu kihelkonna kirjanduslik-kodulooline antoloogia / Koost. Helmut Elstrok; Tead.toim. Oskar Kuningas

  18. Foundations of health psychology

    National Research Council Canada - National Science Library

    Friedman, Howard S; Silver, Roxane Cohen

    2007-01-01

    ... and Effective Treatment 9 Adjustment to Chronic Disease: Progress and Promise in Research Annette L. Stanton and Tracey A. Revenson 203 10 Aging and Health 234 Karen S. Rook, Susan T. Charles, and...

  19. 77 FR 51845 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-27

    .... Miska (MN), Susan L. Mosel (WI), Mark T. L. Owings (KS), Jacob D. Oxford (ID), Derek W. Palmer (MA), Robert D. Regavich (NJ), Jack W. Schlichting (MN), Lonnie H. Shere (WA), Craig A. Trimmer (OH), Lisa E...

  20. 76 FR 57036 - Notice of Open Meeting of the Advisory Committee of the Export-Import Bank of the United States...

    Science.gov (United States)

    2011-09-15

    ..., and you may contact Susan Houser to be placed on an attendee list. If any person wishes auxiliary aids (such as a sign language interpreter) or other special accommodations, please contact, prior to...

  1. 75 FR 29759 - Notice of Open Meeting of the Advisory Committee of the Export-Import Bank of the United States...

    Science.gov (United States)

    2010-05-27

    ... building, and you may contact Susan Houser to be placed on an attendee list. If any person wishes auxiliary aids (such as a sign language interpreter) or other special accommodations, please contact, prior to...

  2. Eesti president Toomas H. Ilves Pennsylvania ülikooli ajakirjas / Airi Vaga

    Index Scriptorium Estoniae

    Vaga, Airi, 1940-

    2008-01-01

    University of Pennsylvania ajakirjas "The Pennsylvania Gazette" ilmunud artiklist "From Estonian Exile to Executive Office", autor Susan Frith - järjekordsest võimalusest tutvustada Eestit ja eestlasi USA ülikoolide kaudu

  3. Ämbliku jäljed kivimüüril / Sigrid Saarep

    Index Scriptorium Estoniae

    Saarep, Sigrid, 1963-

    2009-01-01

    Suurbritannia paviljonis 53. Veneetsia kunstibiennaalil esinevad kunstnikud Steve McQueen, John Cale (Wales), Martin Boyce (Šotimaa) ja Susan MacWilliam (Põhja-Iirimaa). Videokunstnik Steve McQueeni filmist "Giardini" (2009)

  4. 77 FR 64794 - Membership of the Economic Development Administration Performance Review Board

    Science.gov (United States)

    2012-10-23

    ... INFORMATION CONTACT: Ronda L. Holbrook, U.S. Department of Commerce, Human Resources Operations Center... Management, Minority Business Development Agency, career. Dated: October 11, 2012. Susan Boggs, Director, Office of Staffing, Recruitment and Classification, Department of Commerce Human Resources Operations...

  5. African Journal of AIDS Research - Vol 13, No 4 (2014)

    African Journals Online (AJOL)

    Clemens Ley, Lloyd Leach, María Rato Barrio, Susan Bassett ... Charles Omondi Olang'o, Erick Nyambedha, Jens Aagaard-Hansen ... Bierhuizen, Arlinda Zango, Nienke Veldhuijzen, Fidelina Cumbe, Paul J Feldblum, Janneke van de Wijgert.

  6. Investigation of manganese homeostasis in dogs with anaemia and ...

    African Journals Online (AJOL)

    Investigation of manganese homeostasis in dogs with anaemia and chronic enteropathy. Marisa da Fonseca Ferreira, Arielle Elizabeth Ann Aylor, Richard John Mellanby, Susan Mary Campbell, Adam George Gow ...

  7. 78 FR 45538 - The Patient Preference Initiative: Incorporating Patient Preference Information Into the Medical...

    Science.gov (United States)

    2013-07-29

    ... beginning at 7 a.m. If you need special accommodations due to a disability, please contact Susan Monahan... within the Total Product Life Cycle regulatory paradigm? In what ways should it not be used? What...

  8. 76 FR 72013 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Notice of Filing of...

    Science.gov (United States)

    2011-11-21

    ...''); Colette J. Irwin-Knott, CIPFA, President, National Association of Independent Public Finance Advisors...''); and Susan Gaffney, Director, Federal Liaison Center, Government Finance Officers Association, dated... principles of trade, to foster cooperation and coordination with persons engaged in regulating, clearing...

  9. AFRICOM: Does Location Matter?

    Science.gov (United States)

    2009-03-01

    Decision Model,” 242-244. 26 Susan Hesse Owen & Mark S. Daskin , “Strategic Facility Location: A Review,” European Journal of Operational Research...Susan Hesse & Mark S. Daskin . “Strategic Facility Location: A Review,” European Journal of Operational Research 111 (1998), 423-447. Paye-Layeleh...ES) N/ A 10. SPONSORING/MONITORING AGENCY REPORT NUMBER 11. SUPPLEMENTARY NOTES The views expressed in this thesis are those of the author and

  10. The NATO SOF Air Wing: A Basing Decision

    Science.gov (United States)

    2012-12-01

    11 Susan Hesse Owen & Mark S. Daskin , “Strategic Facility Location: A Review,” European Journal of Operational Research 111, (1998), 423. 6 the...Journal of Travel Research 45, (2006):167–174. Owen, Susan Hesse and Daskin , Mark S. “Strategic Facility Location: A Review.” European Journal of...WING: A BASING DECISION by James M. Cox December 2012 Thesis Advisor: William Fox Second Reader: Brian Greenshields THIS PAGE

  11. Guilt-Free War: Post-Traumatic Stress and an Ethical Framework for Battlefield Decisions

    Science.gov (United States)

    2015-12-01

    Susan Wolf, “ Moral Obligations and Social Command,” in Metaphysics and the Good: Themes from the Philosophy of Robert Merrihew Adams, edited by...1–18. Wolf, Susan. “ Moral Obligations and Social Command.” In Metaphysics and the Good: Themes from the Philosophy of Robert Merrihew Ad- ams, edited...Analysis of Recent Studies 5 Discussion of Various Approaches to Addressing Moral Injuries 7 Recommendations 17 Conclusion 19 Abbreviations 25

  12. Measuring the Foundation of Homeland Security

    Science.gov (United States)

    2007-03-01

    Pirak Kevin Eack Susan Pyle Chuck Eaneff Joseph Saitta Susan Fernandez Shelly Schechter Helen Fitzpatrick Rick Schwein Jay...multiple disciplines. The scope of this literature review is to cast a broad net and then narrow to specific literature related to Homeland Security...Suez Canal. His successes as a planner, diplomat and promoter made him the most celebrated man in Europe. Because of these successes, De Lesseps

  13. Critical Rare Earths, National Security, and U.S.-China Interactions: A Portfolio Approach to Dysprosium Policy Design

    Science.gov (United States)

    2015-01-01

    from Donald and Susan Rice , both funds which enabled me to focus on the dissertation. I thank Dean Susan Marquis for her dedication to the growth of...quota of 89,2000 tonnes (Table 2.2). The sprawling black market not only prevents Beijing’s efforts to bring the production under its levers to...yttrium are often used for pigmentation for consumer products such as paint and sunglasses. REE-based lasers are used for cosmetic , epidermal, and

  14. Wanna play?

    DEFF Research Database (Denmark)

    Sanderhoff, Merete

    2015-01-01

    Part of the online publication series CODE | WORDS. Technology and Theory in the Museum, edited by Ed Rodley (Peabody Essex Museum), Robert Stein (Dallas Museum of Art) and Susan Cairns (Baltimore Museum of Art)......Part of the online publication series CODE | WORDS. Technology and Theory in the Museum, edited by Ed Rodley (Peabody Essex Museum), Robert Stein (Dallas Museum of Art) and Susan Cairns (Baltimore Museum of Art)...

  15. Possible Regulatory Improvements of the American Housing Finance System

    DEFF Research Database (Denmark)

    Lunde, Jens

    2018-01-01

    Book review of: Susan M. Wachter and Joseph Tracy (eds.): Principles of Housing Finance Reform. PENN—University of Pennsylvania Press, Philadelphia, 282 pp, $65.00s, ISBN: 978-0-8122-4862-3......Book review of: Susan M. Wachter and Joseph Tracy (eds.): Principles of Housing Finance Reform. PENN—University of Pennsylvania Press, Philadelphia, 282 pp, $65.00s, ISBN: 978-0-8122-4862-3...

  16. Characterizing Musculoskeletal Injury among Aeromedical Evacuation Personnel: An Observational Study

    Science.gov (United States)

    2016-09-28

    Jennifer Serres, PhD; Col Susan Dukes, PhD; Molly Wade, MS; Brittany Fouts, MS; Mandy Cowgill, MS; Daniel Pohlman, BS September 2016...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jennifer Serres, Susan Dukes, Molly Wade, Brittany Fouts, Mandy... environment . 2.0 INTRODUCTION Musculoskeletal injuries (MSIs) result from the cumulative trauma associated with repetitive and physically

  17. 78 FR 29612 - Prevailing Rate Systems; Redefinition of the Minneapolis-St. Paul, MN, and Southwestern Wisconsin...

    Science.gov (United States)

    2013-05-21

    ... Renville Rice Sherburne Sibley Stearns Steele Stevens Swift Todd Traverse Wabasha Wadena Waseca Watonwan... Langlade Lincoln Marathon Marinette Menominee Oneida Pepin Portage Price Richland Rusk Shawano Taylor...

  18. 77 FR 67020 - Performance Review Board Appointments

    Science.gov (United States)

    2012-11-08

    ..., Tommy Beck, Richard Belin, Alletta Berrigan, Michael Black, Michael Black, Steven Blanchard, Mary Josie..., Robert Reidenbach, Dennis Reynolds, Michael Rice, Bryan Roberson, Edwin Rountree, Carl Russ, David...

  19. Think Tek Learning Lab, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Steven Winter Associates, Inc. (SWA) proposes to develop a nation-wide informal technology education program that integrates math, science, engineering and...

  20. [Investigation on the interaction between pentadecafluorooctanoic acid and human serum albumin by capillary electrophoresis].

    Science.gov (United States)

    Gu, Yi; Guo, Ming; Lü, Da; Hou, Ping; Yin, Xinxin

    2018-01-08

    Capillary electrophoresis (CE) has been used to establish the analytical method of interaction between pentadecafluorooctanoic acid (PFOA) and human serum albumin (HSA). Under the physiological conditions, the interaction model of PFOA and HSA were constructed. Mobility method, plug-plug kinetic (PPK) method and simplified Hummel-Dreyer method were used to determine the interaction between derivatives and HSA. Non-linear regression, Scatchard equation and Klotz equation were adopted to obtain the interaction parameters. The results showed that all the three methods can be used to analyze the interaction of PFOA-HSA system. According to the interaction parameters, the most suitable CE method is simplified Hummel-Dreyer method while the most suitable theoretical equation is non-linear regression. The binding parameters indicated that the interaction of PFOA-HSA system has only one type of binding sites and the binding is stable. The research results have illustrated the interaction between HSA and PFOA, and provided a beneficial reference for in-depth research of the toxic mechanism of PFOA.