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Sample records for survived challenge passed

  1. Survival Rates of Juvenile Salmonids Passing Through the Bonneville Dam and Spillway in 2008

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R.; Weiland, Mark A.; Faber, Derrek M.; Deng, Zhiqun; Johnson, Gary E.; Hughes, James S.; Zimmerman, Shon A.; Monter, Tyrell J.; Cushing, Aaron W.; Wilberding, Matthew C.; Durham, Robin E.; Townsend, R. L.; Skalski, J. R.; Buchanan, Rebecca A.; Kim, Jina; Fischer, Eric S.; Meyer, Matthew M.; McComas, Roy L.; Everett, Jason

    2009-12-28

    This report describes a 2008 acoustic telemetry survival study conducted by the Pacific Northwest National Laboratory for the Portland District of the U.S. Army Corps of Engineers. The study estimated the survival of juvenile Chinook salmon and steelhead passing Bonneville Dam (BON) and its spillway. Of particular interest was the relative survival of smolts detected passing through end spill bays 1-3 and 16-18, which had deep flow deflectors immediately downstream of spill gates, versus survival of smolts passing middle spill bays 4-15, which had shallow flow deflectors.

  2. Survival of Juvenile Chinook Salmon Passing the Bonneville Dam Spillway in 2007

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R.; Weiland, Mark A.; Hughes, James S.; Zimmerman, Shon A.; Durham, Robin E.; Fischer, Eric S.; Kim, Jina; Townsend, R. L.; Skalski, J. R.; Buchanan, Rebecca A.; McComas, Roy L.

    2008-12-01

    The U.S. Army Corps of Engineers Portland District (CENWP) funds numerous evaluations of fish passage and survival on the Columbia River. In 2007, the CENWP asked Pacific Northwest National Laboratory to conduct an acoustic telemetry study to estimate the survival of juvenile Chinook salmon passing the spillway at Bonneville Dam. This report documents the study results which are intended to be used to improve the conditions juvenile anadromous fish experience when passing through the dams that the Corps operates on the river.

  3. Survival and Passage of Juvenile Chinook Salmon and Steelhead Passing through Bonneville Dam, 2011

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Batten, G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cushing, Aaron W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kim, Jin A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Gary E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Skalski, J. R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Townsend, Richard L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Seaburg, Adam [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weiland, Mark A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Woodley, Christa M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hughes, James S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carlson, Thomas J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carpenter, Scott M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Zhiqun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Etherington, D. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fischer, Eric S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fu, Tao [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Greiner, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hennen, Matthew J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Martinez, Jayson J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mitchell, T. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rayamajhi, Bishes [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zimmerman, Shon A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-02-15

    Pacific Northwest National Laboratory (PNNL) and subcontractors conducted an acoustic-telemetry study of juvenile salmonid fish passage and survival at Bonneville Dam in 2011. The study was conducted to assess the readiness of the monitoring system for official compliance studies under the 2008 Biological Opinion and Fish Accords and to assess performance measures including route-specific fish passage proportions, travel times, and survival based upon a virtual/paired-release model. The study relied on releases of live Juvenile Salmon Acoustic Telemetry System tagged smolts in the Columbia River and used acoustic telemetry to evaluate the approach, passage, and survival of passing juvenile salmon using a virtual release, paired reference release survival model. This study supports the U.S. Army Corps of Engineers’ continual effort to improve conditions for juvenile anadromous fish passing through Columbia River dams.

  4. Survival and Passage of Juvenile Chinook Salmon and Steelhead Passing through Bonneville Dam, 2010

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R.; Weiland, Mark A.; Hughes, James S.; Woodley, Christa M.; Deng, Zhiqun; Carlson, Thomas J.; Kim, Jin A.; Royer, Ida M.; Batten, George W.; Cushing, Aaron W.; Carpenter, Scott M.; Etherington, D. J.; Faber, Derrek M.; Fischer, Eric S.; Fu, Tao; Hennen, Matthew J.; Mitchell, Tyler; Monter, Tyrell J.; Skalski, John R.; Townsend, Richard L.; Zimmerman, Shon A.

    2011-12-01

    Pacific Northwest National Laboratory (PNNL) and subcontractors conducted an acoustic-telemetry study of juvenile salmonid fish passage and survival at Bonneville Dam in 2010. The study was conducted to assess the readiness of the monitoring system for official compliance studies under the 2008 Biological Opinion and Fish Accords and to assess performance measures including route-specific fish passage proportions, travel times, and survival based upon a single-release model. This also was the last year of evaluation of effects of a behavioral guidance device installed in the Powerhouse 2 forebay. The study relied on releases of live Juvenile Salmon Acoustic Telemetry System tagged smolts in the Columbia River and used acoustic telemetry to evaluate the approach, passage, and survival of passing juvenile salmon. This study supports the U.S. Army Corps of Engineers continual effort to improve conditions for juvenile anadromous fish passing through Columbia River dams.

  5. Survival and Passage of Juvenile Chinook Salmon and Steelhead Passing Through Bonneville Dam, 2010

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R.; Weiland, Mark A.; Hughes, James S.; Woodley, Christa M.; Deng, Zhiqun; Carlson, Thomas J.; Kim, Jin A.; Royer, Ida M.; Batten, George W.; Cushing, Aaron W.; Carpenter, Scott M.; Etherington, D. J.; Faber, Derrek M.; Fischer, Eric S.; Fu, Tao; Hennen, Matthew J.; Mitchell, T. D.; Monter, Tyrell J.; Skalski, J. R.; Townsend, Richard L.; Zimmerman, Shon A.

    2012-09-01

    Pacific Northwest National Laboratory (PNNL) and subcontractors conducted an acoustic-telemetry study of juvenile salmonid fish passage and survival at Bonneville Dam in 2010. The study was conducted to assess the readiness of the monitoring system for official compliance studies under the 2008 Biological Opinion and Fish Accords and to assess performance measures including route-specific fish passage proportions, travel times, and survival based upon a single-release model. This also was the last year of evaluation of effects of a behavioral guidance device installed in the Powerhouse 2 forebay. The study relied on releases of live Juvenile Salmon Acoustic Telemetry System tagged smolts in the Columbia River and used acoustic telemetry to evaluate the approach, passage, and survival of passing juvenile salmon. This study supports the U.S. Army Corps of Engineers continual effort to improve conditions for juvenile anadromous fish passing through Columbia River dams.

  6. Estimates for the probability of survival of electrons in passing through a radiator

    International Nuclear Information System (INIS)

    Loos, J.

    1977-01-01

    Some calculations on the survival of electrons passing through various radiator thicknesses are tabulated. The results of these calculations should serve as a guide for expected attenuation of electrons in the beam when various Pb radiators are inserted

  7. Challenges in the estimation of Net SURvival: The CENSUR working survival group.

    Science.gov (United States)

    Giorgi, R

    2016-10-01

    Net survival, the survival probability that would be observed, in a hypothetical world, where the cancer of interest would be the only possible cause of death, is a key indicator in population-based cancer studies. Accounting for mortality due to other causes, it allows cross-country comparisons or trends analysis and provides a useful indicator for public health decision-making. The objective of this study was to show how the creation and formalization of a network comprising established research teams, which already had substantial and complementary experience in both cancer survival analysis and methodological development, make it possible to meet challenges and thus provide more adequate tools, to improve the quality and the comparability of cancer survival data, and to promote methodological transfers in areas of emerging interest. The Challenges in the Estimation of Net SURvival (CENSUR) working survival group is composed of international researchers highly skilled in biostatistics, methodology, and epidemiology, from different research organizations in France, the United Kingdom, Italy, Slovenia, and Canada, and involved in French (FRANCIM) and European (EUROCARE) cancer registry networks. The expected advantages are an interdisciplinary, international, synergistic network capable of addressing problems in public health, for decision-makers at different levels; tools for those in charge of net survival analyses; a common methodology that makes unbiased cross-national comparisons of cancer survival feasible; transfer of methods for net survival estimations to other specific applications (clinical research, occupational epidemiology); and dissemination of results during an international training course. The formalization of the international CENSUR working survival group was motivated by a need felt by scientists conducting population-based cancer research to discuss, develop, and monitor implementation of a common methodology to analyze net survival in order

  8. Challenges in conducting post-authorisation safety studies (PASS): A vaccine manufacturer's view.

    Science.gov (United States)

    Cohet, Catherine; Rosillon, Dominique; Willame, Corinne; Haguinet, Francois; Marenne, Marie-Noëlle; Fontaine, Sandrine; Buyse, Hubert; Bauchau, Vincent; Baril, Laurence

    2017-05-25

    Post-authorisation safety studies (PASS) of vaccines assess or quantify the risk of adverse events following immunisation that were not identified or could not be estimated pre-licensure. The aim of this perspective paper is to describe the authors' experience in the design and conduct of twelve PASS that contributed to the evaluation of the benefit-risk of vaccines in real-world settings. We describe challenges and learnings from selected PASS of rotavirus, malaria, influenza, human papillomavirus and measles-mumps-rubella-varicella vaccines that assessed or identified potential or theoretical risks, which may lead to changes to risk management plans and/or to label updates. Study settings include the use of large healthcare databases and de novo data collection. PASS methodology is influenced by the background incidence of the outcome of interest, vaccine uptake, availability and quality of data sources, identification of the at-risk population and of suitable comparators, availability of validated case definitions, and the frequent need for case ascertainment in large databases. Challenges include the requirement for valid exposure and outcome data, identification of, and access to, adequate data sources, and mitigating limitations including bias and confounding. Assessing feasibility is becoming a key step to confirm that study objectives can be met in a timely manner. PASS provide critical information for regulators, public health agencies, vaccine manufacturers and ultimately, individuals. Collaborative approaches and synergistic efforts between vaccine manufacturers and key stakeholders, such as regulatory and public health agencies, are needed to facilitate access to data, and to drive optimal study design and implementation, with the aim of generating robust evidence. Copyright © 2017 GSK Biologicals SA. Published by Elsevier Ltd.. All rights reserved.

  9. Survival of microbial cultures on mineral while passing dense layers of the atmosphere

    Science.gov (United States)

    Viacheslav, Ilyin; Novikova, Nataliya; Deshevaya, Elena; Polikarpov, Nikolay; Slobodkin, Alexander; Gavrilov, Sergey; Ionov, Viktor; Morozova, Julia

    The purpose of the experiment is to study the possibility of extremophilic microorganisms survival in meteorite-like mineral while passing through the dense layers of the atmosphere. For this purpose cultures of bacteria were placed into the holes made in basalt pieces fixed to the outer wall of the spacecraft Bion M1. Control: similar materials placed in the outer container, prevented from overheating in the dense layers of the atmosphere by lid. In the flight experiment five strains of thermophilic bacteria and 2 strains of hyperthermophilic archaea from the collection of the Institute of Microbiology, RAS were used. In addition, microorganisms were selected from the collection of the Institute of Biomedical Problems, isolated from the environment objects of ISS: 10 fungal cultures and a culture of bacteria Bacillus pumilus. For thermophiles and hyperthermophiles the ability to redox interactions with minerals is considered as a priority physiological property. Ability of thermophiles to anaerobic growth also meets the conditions of the experiment - testing cell survival of microorganisms in the conditions of extraterrestrial space and ancient anaerobic atmosphere of the Earth. After 30-days flight in orbit control all spore-forming microorganisms have been successfully survived. Hyperthermophilic archaea growth in all control was significantly less intensive. Meanwhile, in one experimental samples there was obtained signs of survival of spore forming bacteria culture Carboxydocella ferrireducens. However, the maximum concentration of cells was 2 orders of magnitude below the values characteristic of an actively growing culture of the microorganism. Due to damage of holes in the stone, this result was obtained only in one replicate and for final prove of survival of C. ferrireducens when returning through the dense layers of the atmosphere it is necessary to repeat the experiment It should be noted that an important indicator of the possibility of survival of C

  10. Analyses of potential factors affecting survival of juvenile salmonids volitionally passing through turbines at McNary and John Day Dams, Columbia River

    Science.gov (United States)

    Beeman, John; Hansel, Hal; Perry, Russell; Hockersmith, Eric; Sandford, Ben

    2011-01-01

    This report describes analyses of data from radio- or acoustic-tagged juvenile salmonids passing through hydro-dam turbines to determine factors affecting fish survival. The data were collected during a series of studies designed to estimate passage and survival probabilities at McNary (2002-09) and John Day (2002-03) Dams on the Columbia River during controlled experiments of structures or operations at spillways. Relatively few tagged fish passed turbines in any single study, but sample sizes generally were adequate for our analyses when data were combined from studies using common methods over a series of years. We used information-theoretic methods to evaluate biological, operational, and group covariates by creating models fitting linear (all covariates) or curvilinear (operational covariates only) functions to the data. Biological covariates included tag burden, weight, and water temperature; operational covariates included spill percentage, total discharge, hydraulic head, and turbine unit discharge; and group covariates included year, treatment, and photoperiod. Several interactions between the variables also were considered. Support of covariates by the data was assessed by comparing the Akaike Information Criterion of competing models. The analyses were conducted because there was a lack of information about factors affecting survival of fish passing turbines volitionally and the data were available from past studies. The depth of acclimation, tag size relative to fish size (tag burden), turbine unit discharge, and area of entry into the turbine intake have been shown to affect turbine passage survival of juvenile salmonids in other studies. This study indicates that turbine passage survival of the study fish was primarily affected by biological covariates rather than operational covariates. A negative effect of tag burden was strongly supported in data from yearling Chinook salmon at John Day and McNary dams, but not for subyearling Chinook salmon or

  11. Pathological and immunological responses associated with differential survival of Chinook salmon following Renibacterium salmoninarum challenge

    Science.gov (United States)

    Metzger, David C.; Elliott, Diane G.; Wargo, Andrew; Park, Linda K.; Purcell, Maureen K.

    2010-01-01

    Chinook salmon Oncorhynchus tshawytscha are highly susceptible to Renibacterium salmoninarum, the causative agent of bacterial kidney disease (BKD). Previously we demonstrated that introduced Chinook salmon from Lake Michigan, Wisconsin (WI), USA, have higher survival following R. salmoninarum challenge relative to the progenitor stock from Green River, Washington, USA. In the present study, we investigated the pathological and immunological responses that are associated with differential survival in the 2 Chinook salmon stocks following intra-peritoneal R. salmoninarum challenge of 2 different cohort years (2003 and 2005). Histological evaluation revealed delayed appearance of severe granulomatous lesions in the kidney and lower overall prevalence of membranous glomerulopathy in the higher surviving WI stock. The higher survival WI stock had a lower bacterial load at 28 d post-infection, as measured by reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR). However, at all other time points, bacterial load levels were similar despite higher mortality in the more susceptible Green River stock, suggesting the possibility that the stocks may differ in their tolerance to infection by the bacterium. Interferon-γ, inducible nitric oxide synthase (iNOS), Mx-1, and transferrin gene expression were up-regulated in both stocks following challenge. A trend of higher iNOS gene expression at later time points (≥28 d post-infection) was observed in the lower surviving Green River stock, suggesting the possibility that higher iNOS expression may contribute to greater pathology in that stock.

  12. Fabrication of seamless calandria tubes by cold pilgering route using 3-pass and 2-pass schedules

    Science.gov (United States)

    Saibaba, N.

    2008-12-01

    Calandria tube is a large diameter, extremely thin walled zirconium alloy tube which has diameter to wall thickness ratio as high as 90-95. Such tubes are conventionally produced by the 'welded route', which involves extrusion of slabs followed by a series of hot and cold rolling passes, intermediate anneals, press forming of sheets into circular shape and closing the gap by TIG welding. Though pilgering is a well established process for the fabrication of seamless tubes, production of extremely thin walled tubes offers several challenges during pilgering. Nuclear fuel complex (NFC), Hyderabad, has successfully developed a process for the production of Zircaloy-4 calandria tubes by adopting the 'seamless route' which involves hot extrusion of mother blanks followed by three-pass pilgering or two-pass pilgering schedules. This paper deals with standardization of the seamless route processes for fabrication of calandria tubes, comparison between the tubes produced by 2-pass and 3-pass pilgering schedules, role of ultrasonic test charts for control of process parameters, development of new testing methods for burst testing and other properties.

  13. Fabrication of seamless calandria tubes by cold pilgering route using 3-pass and 2-pass schedules

    International Nuclear Information System (INIS)

    Saibaba, N.

    2008-01-01

    Calandria tube is a large diameter, extremely thin walled zirconium alloy tube which has diameter to wall thickness ratio as high as 90-95. Such tubes are conventionally produced by the 'welded route', which involves extrusion of slabs followed by a series of hot and cold rolling passes, intermediate anneals, press forming of sheets into circular shape and closing the gap by TIG welding. Though pilgering is a well established process for the fabrication of seamless tubes, production of extremely thin walled tubes offers several challenges during pilgering. Nuclear fuel complex (NFC), Hyderabad, has successfully developed a process for the production of Zircaloy-4 calandria tubes by adopting the 'seamless route' which involves hot extrusion of mother blanks followed by three-pass pilgering or two-pass pilgering schedules. This paper deals with standardization of the seamless route processes for fabrication of calandria tubes, comparison between the tubes produced by 2-pass and 3-pass pilgering schedules, role of ultrasonic test charts for control of process parameters, development of new testing methods for burst testing and other properties

  14. Loss of European silver eel passing a hydropower station

    DEFF Research Database (Denmark)

    Pedersen, Michael Ingemann; Jepsen, Niels; Aarestrup, Kim

    2012-01-01

    The aim of this study was to assess escapement success of silver eels, Anguilla anguilla (L.), in a lowland river while passing a reservoir and a hydropower station. It was hypothesized that passage success would be lowest at the hydropower station and that survival and migration speed would...... that within the study period, only 23% of the tagged eels reached the tidal limit, mainly due to difficulties in passing the hydropower dam. With such high loss-rates, the escapement goals set in the management plan cannot be achieved...

  15. A multi-year analysis of passage and survival at McNary Dam, 2004-09

    Science.gov (United States)

    Adams, Noah S.; Walker, C.E.; Perry, R.W.

    2011-01-01

    We analyzed 6 years (2004–09) of passage and survival data collected at McNary Dam to determine how dam operations and environmental conditions affect passage and survival of juvenile salmonids. A multinomial logistic regression was used to examine how environmental variables and dam operations relate to passage behavior of juvenile salmonids at McNary Dam. We used the Cormack-Jolly-Seber release-recapture model to determine how the survival of juvenile salmonids passing through McNary Dam relates to environmental variables and dam operations. Total project discharge and the proportion of flow passing the spillway typically had a positive effect on survival for all species and routes. As the proportion of water through the spillway increased, the number of fish passing the spillway increased, as did overall survival. Additionally, survival generally was higher at night. There was no meaningful difference in survival for fish that passed through the north or south portions of the spillway or powerhouse. Similarly, there was no difference in survival for fish released in the north, middle, or south portions of the tailrace. For subyearling Chinook salmon migrating during the summer season, increased temperatures had a drastic effect on passage and survival. As temperature increased, survival of subyearling Chinook salmon decreased through all passage routes and the number of fish that passed through the turbines increased. During years when the temporary spillway weirs (TSWs) were installed, passage through the spillway increased for spring migrants. However, due to the changes made in the location of the TSW between years and the potential effect of other confounding environmental conditions, it is not certain if the increase in spillway passage was due solely to the presence of the TSWs. The TSWs appeared to improve forebay survival during years when they were operated.

  16. Passing the Bond Issue (with Related Video)

    Science.gov (United States)

    Erickson, Paul W.

    2011-01-01

    When a bond referendum comes around for a school district, it often is the culmination of years of planning, strategizing and communicating to the public. Especially in these economic times, passing a building referendum is challenging. Complete transparency among the superintendent, school board and community is essential to communicate the…

  17. Survival of Five Strains of Shiga Toxigenic Escherichia coli in a Sausage Fermentation Model and Subsequent Sensitivity to Stress from Gastric Acid and Intestinal Fluid

    Directory of Open Access Journals (Sweden)

    Tone Mari Rode

    2017-01-01

    Full Text Available The ability of foodborne pathogens to exhibit adaptive responses to stressful conditions in foods may enhance their survival when passing through the gastrointestinal system. We aimed to determine whether Escherichia coli surviving stresses encountered during a model dry-fermented sausage (DFS production process exhibit enhanced tolerance and survival in an in vitro gastrointestinal model. Salami sausage batters spiked with five E. coli isolates, including enterohaemorrhagic E. coli strains isolated from different DFS outbreaks, were fermented in a model DFS process (20°C, 21 days. Control batters spiked with the same strains were stored at 4°C for the same period. Samples from matured model sausages and controls were thereafter exposed to an in vitro digestion challenge. Gastric exposure (pH 3 resulted in considerably reduced survival of the E. coli strains that had undergone the model DFS process. This reduction continued after entering intestinal challenge (pH 8, but growth resumed after 120 min. When subjected to gastric challenge for 120 min, E. coli that had undergone the DFS process showed about 2.3 log10⁡​ lower survival compared with those kept in sausage batter at 4°C. Our results indicated that E. coli strains surviving a model DFS process exhibited reduced tolerance to subsequent gastric challenge at low pH.

  18. Recombinant M. bovis BCG expressing the PLD protein promotes survival in mice challenged with a C. pseudotuberculosis virulent strain.

    Science.gov (United States)

    Leal, Karen Silva; de Oliveira Silva, Mara Thais; de Fátima Silva Rezende, Andréa; Bezerra, Francisco Silvestre Brilhante; Begnini, Karine; Seixas, Fabiana; Collares, Tiago; Dellagostin, Odir; Portela, Ricardo Wagner; de Carvalho Azevedo, Vasco Ariston; Borsuk, Sibele

    2018-06-14

    The aim of this study was to evaluate the survival of mice inoculated with M. bovis BCG Pasteur recombinant expressing the PLD protein and challenged with a C. pseudotuberculosis virulent strain. Four groups were immunized with a sterile 0.9% saline solution (G1), 10 6  CFU of M. bovis BCG Pasteur (G2), 10 6  CFU of M. bovis BCG/pld (G3) or 10 6  CFU of M. bovis BCG/pld with a booster with rPLD (G4) and challenged with 10 4 CFU of C. pseudotuberculosis MIC-6 strain. The highest survival rate of 88% was observed in G4, followed by 77% in G3 and 66% in G2. A significant statistical difference was observed in the levels of cytokines IFN-γ and IL-10 in vaccinated groups (G3 and G4) when compared with the control group (G1) (p < 0.05). The results seem promising as the recombinant vaccine elicited a cellular immune response and provided significant survival after a high virulent challenge. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Future-based Static Analysis of Message Passing Programs

    Directory of Open Access Journals (Sweden)

    Wytse Oortwijn

    2016-06-01

    Full Text Available Message passing is widely used in industry to develop programs consisting of several distributed communicating components. Developing functionally correct message passing software is very challenging due to the concurrent nature of message exchanges. Nonetheless, many safety-critical applications rely on the message passing paradigm, including air traffic control systems and emergency services, which makes proving their correctness crucial. We focus on the modular verification of MPI programs by statically verifying concrete Java code. We use separation logic to reason about local correctness and define abstractions of the communication protocol in the process algebra used by mCRL2. We call these abstractions futures as they predict how components will interact during program execution. We establish a provable link between futures and program code and analyse the abstract futures via model checking to prove global correctness. Finally, we verify a leader election protocol to demonstrate our approach.

  20. Factors Affecting Route Selection and Survival of Steelhead Kelts at Snake River Dams in 2012 and 2013

    Energy Technology Data Exchange (ETDEWEB)

    Harnish, Ryan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Colotelo, Alison HA [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Xinya [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ham, Kenneth D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Zhiqun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-12-01

    In 2012 and 2013, Pacific Northwest National Laboratory conducted a study that summarized the passage proportions and route-specific survival rates of steelhead kelts that passed through Federal Columbia River Power System (FCRPS) dams. To accomplish this, a total of 811 steelhead kelts were tagged with Juvenile Salmon Acoustic Telemetry System (JSATS) transmitters. Acoustic receivers, both autonomous and cabled, were deployed throughout the FCRPS to monitor the downstream movements of tagged-kelts. Kelts were also tagged with Passive Integrated Transponder tags to monitor passage through juvenile bypass systems and detect returning fish. The current study evaluated data collected in 2012 and 2013 to identify individual, behavioral, environmental and dam operation variables that were related to passage and survival of steelhead kelts that passed through FCRPS dams. Bayesian model averaging of multivariable logistic regression models was used to identify the environmental, temporal, operational, individual, and behavioral variables that had the highest probability of influencing the route of passage and the route-specific survival probabilities for kelts that passed Lower Granite (LGR), Little Goose (LGS), and Lower Monumental (LMN) dams in 2012 and 2013. The posterior probabilities of the best models for predicting route of passage ranged from 0.106 for traditional spill at LMN to 0.720 for turbine passage at LGS. Generally, the behavior (depth and near-dam searching activity) of kelts in the forebay appeared to have the greatest influence on their route of passage. Shallower-migrating kelts had a higher probability of passing via the weir and deeper-migrating kelts had a higher probability of passing via the JBS and turbines than other routes. Kelts that displayed a higher level of near-dam searching activity had a higher probability of passing via the spillway weir and those that did less near-dam searching had a higher probability of passing via the JBS and

  1. Fish pass assessment by remote control: a novel framework for quantifying the hydraulics at fish pass entrances

    Science.gov (United States)

    Kriechbaumer, Thomas; Blackburn, Kim; Gill, Andrew; Breckon, Toby; Everard, Nick; Wright, Ros; Rivas Casado, Monica

    2014-05-01

    may distract fish away from fish pass entrances. The initial steps of the framework development have focused on the challenge of precise spatial data referencing in areas with limited sky view to navigation satellites. Platform tracking with a motorised Total Station, various satellite-based positioning solutions and simultaneous localisation and mapping (SLAM) based on stereo images have been tested. The effect of errors in spatial data referencing on ADCP-derived maps of flow features and bathymetry will be quantified through simultaneous deployment of these navigation technologies and the ADCP. This will inform the selection of a cost-effective platform positioning system in practice. Further steps will cover the quantification of uncertainties in ADCP data caused by highly turbulent flows and the identification of suitable ADCP data sampling strategies at fish passes. The final framework for fish pass assessment can contribute to an improved understanding of the interaction of fish and the complex hydraulic river environment.

  2. INVESTIGATION OF SINGLE-PASS/DOUBLE-PASS TECHNIQUES ON FRICTION STIR WELDING OF ALUMINIUM

    Directory of Open Access Journals (Sweden)

    N.A.A. Sathari

    2014-12-01

    Full Text Available The aim of this research is to study the effects of single-pass/ double-pass techniques on friction stir welding of aluminium. Two pieces of AA1100 with a thickness of 6.0 mm were friction stir welded using a CNC milling machine at rotational speeds of 1400 rpm, 1600 rpm and 1800 rpm respectively for single-pass and double-pass. Microstructure observations of the welded area were studied using an optical microscope. The specimens were tested by using a tensile test and Vickers hardness test to evaluate their mechanical properties. The results indicated that, at low rotational speed, defects such as ‘surface lack of fill’ and tunnels in the welded area contributed to a decrease in mechanical properties. Welded specimens using double-pass techniques show increasing values of tensile strength and hardness. From this investigation it is found that the best parameters of FSW welded aluminium AA1100 plate were those using double-pass techniques that produce mechanically sound joints with a hardness of 56.38 HV and 108 MPa strength at 1800 rpm compared to the single-pass technique. Friction stir welding, single-pass/ double-pass techniques, AA1100, microstructure, mechanical properties.

  3. Passing and Catching in Rugby.

    Science.gov (United States)

    Namudu, Mike M.

    This booklet contains the fundamentals for rugby at the primary school level. It deals primarily with passing and catching the ball. It contains instructions on (1) holding the ball for passing, (2) passing the ball to the left--standing, (3) passing the ball to the left--running, (4) making a switch pass, (5) the scrum half's normal pass, (6) the…

  4. Impact of carbon cost on wholesale electricity price: A note on price pass-through issues

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Wook [Korea Southern Power Co., 167, Samsung-dong, Gangnam-gu, Seoul 135-791 (Korea); Chattopadhyay, Deb [Saha International, Level 26, 385 Bourke Street, Melbourne, VIC 3000 (Australia); Park, Jong-bae [Electrical Engineering Department, Konkuk University, 1 Hwayang-dong, Kwanggin-gu, Seoul 143-701 (Korea)

    2010-08-15

    Carbon costs - either in the form of a carbon tax or through permit prices in an emissions trading scheme - would ultimately be reflected in higher electricity prices. Carbon cost ''pass-through'' is critical to the survival of existing coal generation assets and has been discussed widely as a measure of business impact in the electricity industry. This paper sets out in a structured way the factors that determine price pass-through and why this may differ greatly across different systems. Although the basic concept of price pass-through is simple, a clear understanding of the underlying factors is critical to developing insights on how carbon cost would impact on existing coal generation businesses. It is shown that pass-through can vary drastically if the underlying dispatch potential of generators varies significantly across alternative emissions reduction scenarios. It can also vary depending on the availability of competing cleaner forms of generation. Pass-through as a measure of business performance is, therefore, hard to generalize across different circumstances and should be interpreted carefully. (author)

  5. CMOS-based carbon nanotube pass-transistor logic integrated circuits

    Science.gov (United States)

    Ding, Li; Zhang, Zhiyong; Liang, Shibo; Pei, Tian; Wang, Sheng; Li, Yan; Zhou, Weiwei; Liu, Jie; Peng, Lian-Mao

    2012-01-01

    Field-effect transistors based on carbon nanotubes have been shown to be faster and less energy consuming than their silicon counterparts. However, ensuring these advantages are maintained for integrated circuits is a challenge. Here we demonstrate that a significant reduction in the use of field-effect transistors can be achieved by constructing carbon nanotube-based integrated circuits based on a pass-transistor logic configuration, rather than a complementary metal-oxide semiconductor configuration. Logic gates are constructed on individual carbon nanotubes via a doping-free approach and with a single power supply at voltages as low as 0.4 V. The pass-transistor logic configurarion provides a significant simplification of the carbon nanotube-based circuit design, a higher potential circuit speed and a significant reduction in power consumption. In particular, a full adder, which requires a total of 28 field-effect transistors to construct in the usual complementary metal-oxide semiconductor circuit, uses only three pairs of n- and p-field-effect transistors in the pass-transistor logic configuration. PMID:22334080

  6. Effect of dietary supplementation with butyrate and probiotic on the survival of Pacific white shrimp after challenge with Vibrio alginolyticus

    Directory of Open Access Journals (Sweden)

    Norha Constanza Bolívar Ramírez

    Full Text Available ABSTRACT This study evaluated the performance, immunology, and survival of the Pacific white shrimp Litopenaeus vannamei to experimental challenge to Vibrio alginolyticus based on the use of the probiotic Lactobacillus plantarum and the combined use of probiotic and butyrate. Four different diets resulted from the addition of additives: butyrate, probiotic, butyrate + probiotic, and control (no additives. The attractiveness of the diets was assessed by the percentage of positive choices and rejections, using a dual-choice Y-maze format aquarium. The shrimps were fed during four weeks and performance parameters, intestinal microbiota, and immunological parameters were all evaluated. Subsequently, the shrimps were challenged with V. alginolyticus and after 48 h, survival and immunological parameters were evaluated. The results showed increased attractiveness and intake, but only with diets supplemented with sodium butyrate. However, other diets were not rejected. No difference in performance or immunological parameters was observed among the different diets. Also, among the treatments, no difference in Vibrio spp., or total heterotrophic bacteria counts, was found in the intestinal tract. However, the lactic acid bacteria count was higher in the intestinal tract of shrimps fed diets supplemented with probiotic. After bacterial challenge, shrimp fed all diets had a greater survival when compared with the control group. Lactobacillus plantarum and sodium butyrate increase the resistance of shrimp to infection with V. alginolyticus, but do so without affecting performance, immunological parameters, or Vibrio spp., and total heterotrophic bacteria counts in the intestinal tract.

  7. Multi-pass spectroscopic ellipsometry

    International Nuclear Information System (INIS)

    Stehle, Jean-Louis; Samartzis, Peter C.; Stamataki, Katerina; Piel, Jean-Philippe; Katsoprinakis, George E.; Papadakis, Vassilis; Schimowski, Xavier; Rakitzis, T. Peter; Loppinet, Benoit

    2014-01-01

    Spectroscopic ellipsometry is an established technique, particularly useful for thickness measurements of thin films. It measures polarization rotation after a single reflection of a beam of light on the measured substrate at a given incidence angle. In this paper, we report the development of multi-pass spectroscopic ellipsometry where the light beam reflects multiple times on the sample. We have investigated both theoretically and experimentally the effect of sample reflectivity, number of reflections (passes), angles of incidence and detector dynamic range on ellipsometric observables tanΨ and cosΔ. The multiple pass approach provides increased sensitivity to small changes in Ψ and Δ, opening the way for single measurement determination of optical thickness T, refractive index n and absorption coefficient k of thin films, a significant improvement over the existing techniques. Based on our results, we discuss the strengths, the weaknesses and possible applications of this technique. - Highlights: • We present multi-pass spectroscopic ellipsometry (MPSE), a multi-pass approach to ellipsometry. • Different detectors, samples, angles of incidence and number of passes were tested. • N passes improve polarization ratio sensitivity to the power of N. • N reflections improve phase shift sensitivity by a factor of N. • MPSE can significantly improve thickness measurements in thin films

  8. Five days of successful oral alimentation for hospitalized patients based upon passing the Yale Swallow Protocol.

    Science.gov (United States)

    Leder, Steven B; Suiter, Debra M

    2014-09-01

    This study aimed to determine the success of oral alimentation and patient retention rate 1 to 5 days after passing the Yale Swallow Protocol. Participants were 200 consecutive acute care inpatients referred for swallow assessment. Inclusion criteria were adequate cognitive abilities to participate safely, completing an oral mechanism examination, and passing the 3-ounce water swallow challenge. Exclusion criteria were altered mental status, failing the 3-ounce challenge, preadmission dysphagia, head-of-bed restrictions alimentation and retention rate. All patients who remained medically and neurologically stable drank thin liquids and ate successfully 1 to 5 days after passing the protocol. Mean (SD) volume of liquid ingested per day was 474.2 (435.5) cc. Patient retention declined steadily from day of testing (n = 200) through post-testing day 5 (n = 95). Passing the Yale Swallow Protocol allowed for initial determination of aspiration risk followed by successful oral alimentation for 1 to 5 days in medically and neurologically stable acute care hospitalized patients and without the need for instrumental dysphagia testing. The decline in patient retention was expected because of increasingly rapid transit through the acute care setting, which often renders longer follow-up problematic. © The Author(s) 2014.

  9. Passage and survival probabilities of juvenile Chinook salmon at Cougar Dam, Oregon, 2012

    Science.gov (United States)

    Beeman, John W.; Evans, Scott D.; Haner, Philip V.; Hansel, Hal C.; Hansen, Amy C.; Smith, Collin D.; Sprando, Jamie M.

    2014-01-01

    This report describes studies of juvenile-salmon dam passage and apparent survival at Cougar Dam, Oregon, during two operating conditions in 2012. Cougar Dam is a 158-meter tall rock-fill dam used primarily for flood control, and passes water through a temperature control tower to either a powerhouse penstock or to a regulating outlet (RO). The temperature control tower has moveable weir gates to enable water of different elevations and temperatures to be drawn through the dam to control water temperatures downstream. A series of studies of downstream dam passage of juvenile salmonids were begun after the National Oceanic and Atmospheric Administration determined that Cougar Dam was impacting the viability of anadromous fish stocks. The primary objectives of the studies described in this report were to estimate the route-specific fish passage probabilities at the dam and to estimate the survival probabilities of fish passing through the RO. The first set of dam operating conditions, studied in November, consisted of (1) a mean reservoir elevation of 1,589 feet, (2) water entering the temperature control tower through the weir gates, (3) most water routed through the turbines during the day and through the RO during the night, and (4) mean RO gate openings of 1.2 feet during the day and 3.2 feet during the night. The second set of dam operating conditions, studied in December, consisted of (1) a mean reservoir elevation of 1,507 ft, (2) water entering the temperature control tower through the RO bypass, (3) all water passing through the RO, and (4) mean RO gate openings of 7.3 feet during the day and 7.5 feet during the night. The studies were based on juvenile Chinook salmon (Oncorhynchus tshawytscha) surgically implanted with radio transmitters and passive integrated transponder (PIT) tags. Inferences about general dam passage percentage and timing of volitional migrants were based on surface-acclimated fish released in the reservoir. Dam passage and apparent

  10. Ultrastructural evaluation of multiple pass low energy versus single pass high energy radio-frequency treatment.

    Science.gov (United States)

    Kist, David; Burns, A Jay; Sanner, Roth; Counters, Jeff; Zelickson, Brian

    2006-02-01

    The radio-frequency (RF) device is a system capable of volumetric heating of the mid to deep dermis and selective heating of the fibrous septa strands and fascia layer. Clinically, these effects promote dermal collagen production, and tightening of these deep subcutaneous structures. A new technique of using multiple low energy passes has been described which results in lower patient discomfort and fewer side effects. This technique has also been anecdotally described as giving more reproducible and reliable clinical results of tissue tightening and contouring. This study will compare ultrastructural changes in collagen between a single pass high energy versus up to five passes of a multiple pass lower energy treatment. Three subjects were consented and treated in the preauricular region with the RF device using single or multiple passes (three or five) in the same 1.5 cm(2) treatment area with a slight delay between passes to allow tissue cooling. Biopsies from each treatment region and a control biopsy were taken immediately, 24 hours or 6 months post treatment for electron microscopic examination of the 0-1 mm and 1-2 mm levels. Sections of tissue 1 mm x 1 mm x 80 nm were examined with an RCA EMU-4 Transmission Electron Microscope. Twenty sections from 6 blocks from each 1 mm depth were examined by 2 blinded observers. The morphology and degree of collagen change in relation to area examined was compared to the control tissue, and estimated using a quantitative scale. Ultrastructural examination of tissue showed that an increased amount of collagen fibril changes with increasing passes at energies of 97 J (three passes) and 122 J (five passes), respectively. The changes seen after five multiple passes were similar to those detected after much more painful single pass high-energy treatments. This ultrastructural study shows changes in collagen fibril morphology with an increased effect demonstrated at greater depths of the skin with multiple low-fluence passes

  11. TPG bus passes

    CERN Multimedia

    Staff Association

    2013-01-01

    The CERN Staff Association will stop selling TPG bus passes. All active and retired members of the CERN personnel will be able to purchase Unireso bus passes from the CERN Hostel - Building 39 (Meyrin site) from 1st February 2013. For more information: https://cds.cern.ch/journal/CERNBulletin/2013/04/Announcements/1505279?ln=en

  12. WebPASS Explorer (HR Personnel Management)

    Data.gov (United States)

    US Agency for International Development — WebPass Explorer (WebPASS Framework): USAID is partnering with DoS in the implementation of their WebPass Post Personnel (PS) Module. WebPassPS does not replace...

  13. "Which pass is better?" Novel approaches to assess passing effectiveness in elite soccer.

    Science.gov (United States)

    Rein, Robert; Raabe, Dominik; Memmert, Daniel

    2017-10-01

    Passing behaviour is a key property of successful performance in team sports. Previous investigations however have mainly focused on notational measurements like total passing frequencies which provide little information about what actually constitutes successful passing behaviour. Consequently, this has hampered the transfer of research findings into applied settings. Here we present two novel approaches to assess passing effectiveness in elite soccer by evaluating their effects on majority situations and space control in front of the goal. Majority situations are assessed by calculating the number of defenders between the ball carrier and the goal. Control of space is estimated using Voronoi-diagrams based on the player's positions on the pitch. Both methods were applied to position data from 103 German First division games from the 2011/2012, 2012/2013 and 2014/2015 seasons using a big data approach. The results show that both measures are significantly related to successful game play with respect to the number of goals scored and to the probability of winning a game. The results further show that on average passes from the mid-field into the attacking area are most effective. The presented passing efficiency measures thereby offer new opportunities for future applications in soccer and other sports disciplines whilst maintaining practical relevance with respect to tactical training regimes or game performances analysis. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Design and analysis methods for fish survival experiments based on release-recapture

    National Research Council Canada - National Science Library

    Burnham, Kenneth P

    1987-01-01

    .... The application of the methods developed here is more general, however, as it includes experiments to estimate survival of fish as they pass over spillways or through bypass systems and several dams...

  15. Pass it On – The Path is the Goal

    Directory of Open Access Journals (Sweden)

    Kempf, Petra

    2013-10-01

    Full Text Available Our history is infused with human movement – a phenomenon that has given rise to an imperative relationship between the subject, the environment, and the journeys that unfold while moving. Passing through space is therefore one of the oldest and most practiced forms of human movement. One of our great challenges, however, is the communication and documentation of that experience. This article explores the unfolding of place through the act of mapping by employing storytelling as a means of recording our movements.

  16. Survival after burn in a sub-Saharan burn unit: Challenges and opportunities

    Science.gov (United States)

    Tyson, Anna F.; Boschini, Laura P.; Kiser, Michelle M.; Samuel, Jonathan C.; Mjuweni, Steven N.; Cairns, Bruce A.; Charles, Anthony G.

    2013-01-01

    Background Burns are among the most devastating of all injuries and a major global public health crisis, particularly in sub-Saharan Africa. In developed countries, aggressive management of burns continues to lower overall mortality and increase lethal total body surface area (TBSA) at which 50% of patients die (LA50). However, lack of resources and inadequate infrastructure significantly impede such improvements in developing countries. Methods This study is a retrospective analysis of patients admitted to the burn center at Kamuzu Central Hospital in Lilongwe, Malawi between June 2011 and December 2012. We collected information including patient age, gender, date of admission, mechanism of injury, time to presentation to hospital, total body surface area (TBSA) burn, comorbidities, date and type of operative procedures, date of discharge, length of hospital stay, and survival. We then performed bivariate analysis and logistic regression to identify characteristics associated with increased mortality. Results A total of 454 patients were admitted during the study period with a median age of 4 years (range 0.5 months to 79 years). Of these patients, 53% were male. The overall mean TBSA was 18.5%, and average TBSA increased with age—17% for 0–18 year olds, 24% for 19–60 year olds, and 41% for patients over 60 years old. Scald and flame burns were the commonest mechanisms, 52% and 41% respectively, and flame burns were associated with higher mortality. Overall survival in this population was 82%; however survival reduced with increasing age categories (84% in patients 0–18 years old, 79% in patients 19–60 years old, and 36% in patients older than 60 years). TBSA remained the strongest predictor of mortality after adjusting for age and mechanism of burn. The LA50 for this population was 39% TBSA. Discussion Our data reiterate that burn in Malawi is largely a pediatric disease and that the high burn mortality and relatively low LA50 have modestly improved

  17. Evaluation of Behavioral Guidance Structure on Juvenile Salmonid Passage and Survival at Bonneville Dam in 2009

    Energy Technology Data Exchange (ETDEWEB)

    Faber, Derrek M.; Ploskey, Gene R.; Weiland, Mark A.; Deng, Zhiqun; Hughes, James S.; Kim, Jin A.; Fu, Tao; Fischer, Eric S.; Monter, Tyrell J.; Skalski, J. R.

    2011-03-01

    Pacific Northwest National Laboratory (PNNL) conducted an acoustic-telemetry study at Bonneville Dam in 2009 to evaluate the effects of a behavioral guidance structure (BGS) in the Bonneville Dam second powerhouse forebay on fish passage and survival through the second powerhouse (B2), the dam as a whole, and through the first powerhouse and spillway combined. The BGS was deployed to increase the survival of fish passing through B2 by increasing the percentage of outmigrating smolts entering the B2 Corner Collector (B2CC)—a surface flow outlet known to be a relatively benign route for downstream passage at this dam. The study relied on releases of live Juvenile Salmon Acoustic Telemetry System tagged smolts in the Columbia River and used acoustic telemetry to evaluate the approach, passage, and survival of passing juvenile salmon. Study results indicated that having turbine 11 in service is important for providing flow conditions that are comparable to those observed in pre-BGS years (2004 and 2005) and in 2008. This study supports the U.S. Army Corps of Engineers continual effort to improve conditions for juvenile anadromous fish passing through Columbia River dams.

  18. Photoacoustic Soot Spectrometer (PASS) Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Dubey, M [Los Alamos National Laboratory; Springston, S [Brookhaven National Laboratory; Koontz, A [Pacific Northwest National Laboratory; Aiken, A [Los Alamos National Laboratory

    2013-01-17

    The photoacoustic soot spectrometer (PASS) measures light absorption by aerosol particles. As the particles pass through a laser beam, the absorbed energy heats the particles and in turn the surrounding air, which sets off a pressure wave that can be detected by a microphone. The PASS instruments deployed by ARM can also simultaneously measure the scattered laser light at three wavelengths and therefore provide a direct measure of the single-scattering albedo. The Operator Manual for the PASS-3100 is included here with the permission of Droplet Measurement Technologies, the instrument’s manufacturer.

  19. Academic Training: Surviving in space: the challenges of a manned mission to Mars

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2005-2006 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 26, 27, 28 October from 11:00 to 12:00 - Main Auditorium, bldg. 500 Surviving in space: the challenges of a manned mission to Mars by L. S. Pinsky / Univ. Houston, USA Program : Lecture I: Understanding the Space Radiation Environment Lecture II: Dosimetry and the Effects of the Exposure of Human Tissue to Heavily Ionizing Radiation Lecture III: Modelling the Interaction of the Space Radiation in Spacecraft & Humans, and Assessing the Risks on a Mission to Mars... ENSEIGNEMENT ACADEMIQUE ACADEMIC TRAINING Françoise Benz 73127 academic.training@cern.ch If you wish to participate in one of the following courses, please tell to your supervisor and apply electronically from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Departmental Secretariat or from your DTO (Departmental Training Officer). Applications will be accepted in the order ...

  20. 26 CFR 20.2056(b)-4 - Marital deduction; valuation of interest passing to surviving spouse.

    Science.gov (United States)

    2010-04-01

    ... surviving spouse. (a) In general. The value, for the purpose of the marital deduction, of any deductible... expenses could include executor commissions and attorney fees (except to the extent of commissions or fees... executor properly makes an election under section 2056(b)(7) to treat as qualified terminable interest...

  1. The challenge in treating locally recurrent T3-4 nasopharyngeal carcinoma: the survival benefit and severe late toxicities of re-irradiation with intensity-modulated radiotherapy.

    Science.gov (United States)

    Tian, Yun-Ming; Huang, Wei-Zeng; Yuan, Xia; Bai, Li; Zhao, Chong; Han, Fei

    2017-06-27

    Effective treatments for patients with advanced locally recurrent nasopharyngeal carcinoma (NPC) are limited. This investigation was to determine the potential benefits from re-irradiation by intensity-modulated radiotherapy (IMRT) on survival and the effects of severe late toxicities. A retrospective study was conducted in 245 patients diagnosed with locally recurrent T3-T4 NPC who had undergone re-irradiation with IMRT. Follow-up data was colletedand factors associated with survival and severe late toxicities were analyzed. The 5-year local-regional failure-free survival, distant failure-free survival and overall survival rates were 60.9%, 78.3% and 27.5%, respectively. The presence of severe late complications, recurrent T4 disease and gross tumor volume >30 cm3 were associated with poor survival. The incidences of mucosal necrosis, temporal lobe necrosis, cranial neuropathy and trismus were 22.0%, 14.6%, 27.0% and 14.6% respectively. Re-irradiation with IMRT is an effective choice in patients with locally recurrent T3-T4 NPC. However, the survival benefits can be partly offset by severe late complications and optimum treatments in these patients remain a challenge.

  2. Possibilities of the fish pass restoration

    Science.gov (United States)

    Čubanová, Lea

    2018-03-01

    According to the new elaborated methodology of the Ministry of Environment of the Slovak Republic: Identification of the appropriate fish pass types according to water body typology (2015) each barrier on the river must be passable. On the barriers or structures without fish passes new ones should be design and built and on some water structures with existed but nonfunctional fish passes must be realized reconstruction or restoration of such objects. Assessment should be done in terms of the existing migratory fish fauna and hydraulic conditions. Fish fauna requirements resulting from the ichthyological research of the river section with barrier. Hydraulic conditions must than fulfil these requirements inside the fish pass body.

  3. WebPASS ICASS (HR Personnel Management)

    Data.gov (United States)

    US Agency for International Development — WebPASS Joint Administrative Support Platforms Post Administrative Software Suite - U.S. Department of State Executive Officers application suite. Web.PASS is the...

  4. An experimental evaluation of multi-pass solar air heaters

    Energy Technology Data Exchange (ETDEWEB)

    Satcunanathan, S.; Persad, P.

    1980-12-01

    Three collectors of identical dimensions but operating in the single-pass, two-pass and three-pass modes were tested simultaneously under ambient conditions. It was found that the two-pass air heater was consistently better than the single-pass air heater over the day for the range of mass flow rates considered. It was also found that at a mass flow rate of 0.0095 kg s/sup -1/ m/sup -2/, the thermal performances of the two-pass and three-pass collectors were identical, but at higher flow rates the two-pass collector was superior to the three-pass collector, the superiority decreasing with increasing mass flow rate.

  5. Message passing for quantified Boolean formulas

    International Nuclear Information System (INIS)

    Zhang, Pan; Ramezanpour, Abolfazl; Zecchina, Riccardo; Zdeborová, Lenka

    2012-01-01

    We introduce two types of message passing algorithms for quantified Boolean formulas (QBF). The first type is a message passing based heuristics that can prove unsatisfiability of the QBF by assigning the universal variables in such a way that the remaining formula is unsatisfiable. In the second type, we use message passing to guide branching heuristics of a Davis–Putnam–Logemann–Loveland (DPLL) complete solver. Numerical experiments show that on random QBFs our branching heuristics give robust exponential efficiency gain with respect to state-of-the-art solvers. We also manage to solve some previously unsolved benchmarks from the QBFLIB library. Apart from this, our study sheds light on using message passing in small systems and as subroutines in complete solvers

  6. Oil price pass-through into inflation

    International Nuclear Information System (INIS)

    Chen, Shiu-Sheng

    2009-01-01

    This paper uses data from 19 industrialized countries to investigate oil price pass-through into inflation across countries and over time. A time-varying pass-through coefficient is estimated and the determinants of the recent declining effects of oil shocks on inflation are investigated. The appreciation of the domestic currency, a more active monetary policy in response to inflation, and a higher degree of trade openness are found to explain the decline in oil price pass-through. (author)

  7. Iterative deblending of simultaneous-source data using a coherency-pass shaping operator

    Science.gov (United States)

    Zu, Shaohuan; Zhou, Hui; Mao, Weijian; Zhang, Dong; Li, Chao; Pan, Xiao; Chen, Yangkang

    2017-10-01

    Simultaneous-source acquisition helps greatly boost an economic saving, while it brings an unprecedented challenge of removing the crosstalk interference in the recorded seismic data. In this paper, we propose a novel iterative method to separate the simultaneous source data based on a coherency-pass shaping operator. The coherency-pass filter is used to constrain the model, that is, the unblended data to be estimated, in the shaping regularization framework. In the simultaneous source survey, the incoherent interference from adjacent shots greatly increases the rank of the frequency domain Hankel matrix that is formed from the blended record. Thus, the method based on rank reduction is capable of separating the blended record to some extent. However, the shortcoming is that it may cause residual noise when there is strong blending interference. We propose to cascade the rank reduction and thresholding operators to deal with this issue. In the initial iterations, we adopt a small rank to severely separate the blended interference and a large thresholding value as strong constraints to remove the residual noise in the time domain. In the later iterations, since more and more events have been recovered, we weaken the constraint by increasing the rank and shrinking the threshold to recover weak events and to guarantee the convergence. In this way, the combined rank reduction and thresholding strategy acts as a coherency-pass filter, which only passes the coherent high-amplitude component after rank reduction instead of passing both signal and noise in traditional rank reduction based approaches. Two synthetic examples are tested to demonstrate the performance of the proposed method. In addition, the application on two field data sets (common receiver gathers and stacked profiles) further validate the effectiveness of the proposed method.

  8. Genetic architecture of rainbow trout survival from egg to adult

    NARCIS (Netherlands)

    Vehvilainen, H.; Kause, A.; Quiton, C.; Kuukka-Anttila, H.; Koskinen, H.; Paananen, T.

    2010-01-01

    Survival from birth to a reproductive adult is a challenge that only robust individuals resistant to a variety of mortality factors will overcome. To assess whether survival traits share genetic architecture throughout the life cycle, we estimated genetic correlations for survival within fingerling

  9. Beyond survival: Challenges facing South African automotive component exporters

    Directory of Open Access Journals (Sweden)

    M. J. Naude

    2006-12-01

    Full Text Available Purpose and Objective: The South African automotive component industry faces huge challenges in a very competitive global market. The primary focus of this research article is to determine the challenges facing exporters within this industry with special reference to selected sub-sectors. The challenges are approached from a supply chain perspective only. Problem Investigated: The research problem of this study was to identify these unique challenges and ascertain whether the implementation of a 'philosophy of continuous improvement' could be used as a strategic tool to address the challenges they face in the market. Methodology: This study included a combination of literature review, interviews with managers in the selected sub-groups and questionnaires sent out to determine the challenges facing automotive component exporters. In order to test the content validity and the reliability of the questionnaire, a pilot study was conducted at two organisations that are the main suppliers of automotive filters for passenger vehicles. The non-probability convenience sample technique was used to select the sample and consisted of selected sub-sectors that contribute 64,1% of the total value of automotive component exports in South Africa. Out of twenty-seven questionnaires sent out, twenty (74% response rate were duly completed by the respondents and returned to the researcher. Findings: South Africa faces unique challenges and these are listed and ranked according to priority from most to least important as follows: 1. The reduction of production costs; 2. R/US$ exchange rate effect on the respondent's export sales and profit margin; 3. Exchange rate fluctuations; 4. Threats to the local automotive component market; and 5. Increased competition by way of manufactured imports being sold in the South African market. Value of Research: The study provides recommendations that can be used within the automotive component industry.

  10. Nanomechanical characterization by double-pass force-distance mapping

    Energy Technology Data Exchange (ETDEWEB)

    Dagdas, Yavuz S; Tekinay, Ayse B; Guler, Mustafa O; Dana, Aykutlu [UNAM Institute of Materials Science and Nanotechnology, Bilkent University, 06800 Ankara (Turkey); Necip Aslan, M, E-mail: aykutlu@unam.bilkent.edu.tr [Department of Physics, Istanbul Technical University, Istanbul (Turkey)

    2011-07-22

    We demonstrate high speed force-distance mapping using a double-pass scheme. The topography is measured in tapping mode in the first pass and this information is used in the second pass to move the tip over the sample. In the second pass, the cantilever dither signal is turned off and the sample is vibrated. Rapid (few kHz frequency) force-distance curves can be recorded with small peak interaction force, and can be processed into an image. Such a double-pass measurement eliminates the need for feedback during force-distance measurements. The method is demonstrated on self-assembled peptidic nanofibers.

  11. Nanomechanical characterization by double-pass force-distance mapping

    International Nuclear Information System (INIS)

    Dagdas, Yavuz S; Tekinay, Ayse B; Guler, Mustafa O; Dana, Aykutlu; Necip Aslan, M

    2011-01-01

    We demonstrate high speed force-distance mapping using a double-pass scheme. The topography is measured in tapping mode in the first pass and this information is used in the second pass to move the tip over the sample. In the second pass, the cantilever dither signal is turned off and the sample is vibrated. Rapid (few kHz frequency) force-distance curves can be recorded with small peak interaction force, and can be processed into an image. Such a double-pass measurement eliminates the need for feedback during force-distance measurements. The method is demonstrated on self-assembled peptidic nanofibers.

  12. Operational slack and venture survival

    OpenAIRE

    Azadegan, Arash; Patel, Pankaj; Parida, Vinit

    2013-01-01

    Slack can act as a double-edged sword. While it can buffer against environmental threats to help ensure business continuity, slack canalso be costly and reduce profitability. In this study, we focus on operational slack, the form related to the firm’s production processes. We investigate the role of operational slack on firm survival during its venture stage, when its survival is significantly challenged by environmental threats. Specifically, we explore how change in three types of environme...

  13. Spanish validation of the Premorbid Adjustment Scale (PAS-S).

    Science.gov (United States)

    Barajas, Ana; Ochoa, Susana; Baños, Iris; Dolz, Montse; Villalta-Gil, Victoria; Vilaplana, Miriam; Autonell, Jaume; Sánchez, Bernardo; Cervilla, Jorge A; Foix, Alexandrina; Obiols, Jordi E; Haro, Josep Maria; Usall, Judith

    2013-02-01

    The Premorbid Adjustment Scale (PAS) has been the most widely used scale to quantify premorbid status in schizophrenia, coming to be regarded as the gold standard of retrospective assessment instruments. To examine the psychometric properties of the Spanish version of the PAS (PAS-S). Retrospective study of 140 individuals experiencing a first episode of psychosis (n=77) and individuals who have schizophrenia (n=63), both adult and adolescent patients. Data were collected through a socio-demographic questionnaire and a battery of instruments which includes the following scales: PAS-S, PANSS, LSP, GAF and DAS-sv. The Cronbach's alpha was performed to assess the internal consistency of PAS-S. Pearson's correlations were performed to assess the convergent and discriminant validity. The Cronbach's alpha of the PAS-S scale was 0.85. The correlation between social PAS-S and total PAS-S was 0.85 (p<0.001); while for academic PAS-S and total PAS-S it was 0.53 (p<0.001). Significant correlations were observed between all the scores of each age period evaluated across the PAS-S scale, with a significance value less than 0.001. There was a relationship between negative symptoms and social PAS-S (0.20, p<0.05) and total PAS-S (0.22, p<0.05), but not with academic PAS-S. However, there was a correlation between academic PAS-S and general subscale of the PANSS (0.19, p<0.05). Social PAS-S was related to disability measures (DAS-sv); and academic PAS-S showed discriminant validity with most of the variables of social functioning. PAS-S did not show association with the total LSP scale (discriminant validity). The Spanish version of the Premorbid Adjustment Scale showed appropriate psychometric properties in patients experiencing a first episode of psychosis and who have a chronic evolution of the illness. Moreover, each domain of the PAS-S (social and academic premorbid functioning) showed a differential relationship to other characteristics such as psychotic symptoms, disability

  14. The impact of avoiding cardiopulmonary by-pass during coronary artery bypass surgery in elderly patients: the Danish On-pump Off-pump Randomisation Study (DOORS)

    DEFF Research Database (Denmark)

    Houlind, Kim; Kjeldsen, Bo Juul; Madsen, Susanne Nørgaard

    2009-01-01

    BACKGROUND: Coronary Artery Bypass Graft operation for ischemic heart disease provides improved quality of life and, in some patients, prolonged survival. Concern has, however, been raised about complications that may be related to the use of cardiopulmonary by-pass (CPB) and aortic cross......-clamping. It has been hypothesized that when coronary artery by-pass grafting is performed without the use of CPB, the rate of serious complications is reduced. METHODS/DESIGN: The trial is designed as an open, randomized, controlled, clinical trial with blinded assessment of end-points. Patients at or above 70...... years of age, referred for surgical myocardial revascularisation, are included and randomised to receive coronary artery by-pass grafting either with or without the use of CPB and aortic cross-clamping. Follow-up is performed by clinical, biochemical, electrocardiographic, and angiographic data...

  15. Performance of a surface bypass structure to enhance juvenile steelhead passage and survival at Lower Granite Dam, Washington

    Science.gov (United States)

    Adams, Noah S.; Plumb, John M.; Perry, Russell W.; Rondorf, Dennis W.

    2014-01-01

    An integral part of efforts to recover stocks of Pacific salmon Oncorhynchus spp. and steelhead O. mykiss in Pacific Northwest rivers is to increase passage efficacy and survival of juveniles past hydroelectric dams. As part of this effort, we evaluated the efficacy of a prototype surface bypass structure, the removable spillway weir (RSW), installed in a spillbay at Lower Granite Dam, Washington, on the Snake River during 2002, 2003, 2005, and 2006. Radio-tagged juvenile steelhead were released upstream from the dam and their route of passage through the turbines, juvenile bypass, spillway, or RSW was recorded. The RSW was operated in an on-or-off condition and passed 3–13% of the total discharge at the dam when it was on. Poisson rate models were fit to the passage counts of hatchery- and natural-origin juvenile steelhead to predict the probability of fish passing the dam. Main-effect predictor variables were RSW operation, diel period, day of the year, proportion of flow passed by the spillway, and total discharge at the dam. The combined fish passage through the RSW and spillway was 55–85% during the day and 37–61% during the night. The proportion of steelhead passing through nonturbine routes was 95% when the RSW was on during the day. The ratio of the proportion of steelhead passed to the proportion of water passing the RSW was from 6.3:1 to 10.0:1 during the day and from 2.7:1 to 5.2:1 during the night. Steelhead passing through the RSW exited the tailrace about 15 min faster than fish passing through the spillway. Mark–recapture single-release survival estimates for steelhead passing the RSW ranged from 0.95 to 1.00. The RSW appeared to be an effective bypass structure compared with other routes of fish passage at the dam.

  16. Influence of welding passes on grain orientation – The example of a multi-pass V-weld

    International Nuclear Information System (INIS)

    Ye, Jing; Moysan, Joseph; Song, Sung-Jin; Kim, Hak-Joon; Chassignole, Bertrand; Gueudré, Cécile; Dupond, Olivier

    2012-01-01

    The accurate modelling of grain orientations in a weld is important, when accurate ultrasonic test predictions of a welded assembly are needed. To achieve this objective, Electricité de France (EDF) and the Laboratoire de Caractérisation Non Destructive (LCND) have developed a dedicated code, which makes use of information recorded in the welding procedure. Among the welding parameters recorded, although the order in which the welding passes are made is of primary importance in the welding process, this information is not always well known or accurately described. In the present paper we analyse in greater detail the influence of the order of welding passes, using data obtained from the Centre for Advanced Non Destructive Evaluation (CANDE), derived from a dissimilar metal weld (DMW) with buttering. Comparisons are made using grain orientation measurements on a macrograph. - Highlights: ► Influence of welding process on grain structure is studied using the MINA model. ► For the first time the importance of a slight slope of the layers is evaluated. ► Two orders of passes are compared for the modelling approach. ► A major effect is observed due to a change in the order of passes.

  17. Penetrators for delivering Scientific equipment to minor bodies by flying-pass missions.

    Science.gov (United States)

    Bagrov, Alexander; Martynov, Maxim; Pichkhadze, Konstantin M.; Dolgopolov, Vladimir; Sysoev, Valentin

    Many space missions are planned to have close encounters with Solar system minor bodies as a pass-fly. Short time of such close encounters were effectively used for photographing of these bodies, i.e. for distant investigations only because of large velocities of the encounter. We propose to use high-velocity penetrators to provide contact investigations of the minor bodies in situ. These devices were designed by Lavochkin Association for lunar missions. They were designed for long lived scientific equipment to be placed under surface up to depth 2...3 m. Penetrators could survive under 500 g shock, so the contact velocity was from 90 to 250 m/s, so each of them had booster engine to decelerate orbital velocity. As flying-pass velocity near minor body can be more then 10 km/s, penetrators would hit target at speed above 1 km/s and successfully bear 1500 g. To do so we propose to fulfill whole internal space inside penetrator with distilled water and froze it to temperature - 80°C or lower. At this temperature water ice is as hard as steel, so penetrator will plunge into target like armour-piercing shell. After landing protective ice will be evaporated (particularly due to heating from collision) and all sensitive mechanics will be set free.

  18. Passing the baton

    CERN Multimedia

    2011-01-01

    It was not only in South Korea that batons were being passed last week. While the cream of the world’s athletes were competing in the World Athletics Championships, the cream of the world’s accelerator scientists were on their way to San Sebastian in Spain for the International Particle Accelerator Conference.  One of them was carrying a rather special baton for a handover of a different kind.   When Fermilab’s Vladimir Shiltsev handed the high-energy frontier baton to CERN’s Mike Lamont on Tuesday, it marked the end of an era: a time to look back on the phenomenal contribution the Tevatron has made to particle physics over its 25-year operational lifetime, and the great contribution Fermilab has made over that period to global collaboration in particle physics. There’s always a lot of emotion involved in passing the baton. In athletics, it’s the triumph of wining or the heartbreak of losing. But for this special baton, the...

  19. Analysis of Biomechanical Structure and Passing Techniques in Basketball

    OpenAIRE

    Ricardo E. Izzo; Luca Russo

    2011-01-01

    The basketball is a complex sport, which these days has become increasingly linked to its’ psychophysical aspects rather than to the technical ones. Therefore, it is important to make a through study of the passing techniques from the point of view of the type of the pass and its’ biomechanics. From the point of view of the type of the used passes, the most used is the two-handed chest pass with a frequency of 39.9%. This is followed, in terms of frequency, by one-handed passes – the baseball...

  20. Message Passing Framework for Globally Interconnected Clusters

    International Nuclear Information System (INIS)

    Hafeez, M; Riaz, N; Asghar, S; Malik, U A; Rehman, A

    2011-01-01

    In prevailing technology trends it is apparent that the network requirements and technologies will advance in future. Therefore the need of High Performance Computing (HPC) based implementation for interconnecting clusters is comprehensible for scalability of clusters. Grid computing provides global infrastructure of interconnecting clusters consisting of dispersed computing resources over Internet. On the other hand the leading model for HPC programming is Message Passing Interface (MPI). As compared to Grid computing, MPI is better suited for solving most of the complex computational problems. MPI itself is restricted to a single cluster. It does not support message passing over the internet to use the computing resources of different clusters in an optimal way. We propose a model that provides message passing capabilities between parallel applications over the internet. The proposed model is based on Architecture for Java Universal Message Passing (A-JUMP) framework and Enterprise Service Bus (ESB) named as High Performance Computing Bus. The HPC Bus is built using ActiveMQ. HPC Bus is responsible for communication and message passing in an asynchronous manner. Asynchronous mode of communication offers an assurance for message delivery as well as a fault tolerance mechanism for message passing. The idea presented in this paper effectively utilizes wide-area intercluster networks. It also provides scheduling, dynamic resource discovery and allocation, and sub-clustering of resources for different jobs. Performance analysis and comparison study of the proposed framework with P2P-MPI are also presented in this paper.

  1. Geometrical influences on multi-pass laser forming

    International Nuclear Information System (INIS)

    Edwardson, S P; Abed, E; Bartkowiak, K; Dearden, G; Watkins, K G

    2006-01-01

    Laser forming (LF) offers the industrial promise of controlled shaping of metallic and non-metallic components for prototyping, the correction of design shape or distortion and precision adjustment applications. The potential process advantages include precise incremental adjustment, flexibility of application and no mechanical 'spring-back' effect. To date there has been a considerable amount of work carried out on two-dimensional LF, using multi-pass straight line scan strategies to produce a reasonably controlled bend angle in a number of materials, including aerospace alloys. A key area, however, where there is a limited understanding, is the variation in bend angle per pass during multi-pass LF along a single irradiation track; in particular, the decrease in bend angle per pass after many irradiations for a given set of process parameters. Understanding this is essential if the process is to be fully controlled in a manufacturing environment. The research presented in this paper highlights the current theories as to why this occurs and proposes a further reason based on the geometrical effects of the component deformation, which in turn influences the process parameters per pass. This theory is confirmed through empirical analysis of the 2D LF process

  2. Partition function expansion on region graphs and message-passing equations

    International Nuclear Information System (INIS)

    Zhou, Haijun; Wang, Chuang; Xiao, Jing-Qing; Bi, Zedong

    2011-01-01

    Disordered and frustrated graphical systems are ubiquitous in physics, biology, and information science. For models on complete graphs or random graphs, deep understanding has been achieved through the mean-field replica and cavity methods. But finite-dimensional 'real' systems remain very challenging because of the abundance of short loops and strong local correlations. A statistical mechanics theory is constructed in this paper for finite-dimensional models based on the mathematical framework of the partition function expansion and the concept of region graphs. Rigorous expressions for the free energy and grand free energy are derived. Message-passing equations on the region graph, such as belief propagation and survey propagation, are also derived rigorously. (letter)

  3. Gain claming in single-pass and double-pass L-band erbium-doped fiber amplifiers

    International Nuclear Information System (INIS)

    Harun, S.W.; Ahmad, H.

    2004-01-01

    Gain clamping is demonstrated in single-pass and double-pass long wavelength band erbium-doped fiber amplifiers. A C/L-band wavelength division multiplexing coupler is used in single-pass system to generate a laser at 1566 nm. The gain for the amplifier is clamped at 15.5 dB with gain variation of less than 0.2 dB from input signal power of -40 to -14 dBm with almost negligible noise figure penalty. However, the flatness of gain spectrum is slightly degraded due to the un-optimisation of erbium-doped fiber length. The advantage of this configuration is that the oscillating light does not appear at the output of the amplifier. A highly efficient gain-clamped long wavelength band erbium-doped fiber amplifiers with improved noise figure characteristic is demonstrated by simply adding a broadband conventional band fiber Bragg grating in double pass system. The combination of the fiber Bragg grating and optical circulator has created laser in the cavity for gain clamping. By adjusting the power combination of pumps 1 and 2, the clamped gain level can be controlled. The amplifier gain is clamped at 28.1 dB from -40 to -25 dBm with gain variation of less than 0.5 dB by setting the pumps 1 and 2 at 59.5 and 50.6 mW, respectively. The gain is also flat from 1574 nm to 1604 nm with gain variation of less than 3 dB. The corresponding noise figure varies from 5.6 to 7.6 dB, which is 0.8 to 2.6 dB reduced compared to those of unclamped amplifier (Authors)

  4. Global variations in cancer survival. Study Group on Cancer Survival in Developing Countries.

    Science.gov (United States)

    Sankaranarayanan, R; Swaminathan, R; Black, R J

    1996-12-15

    Population-based cancer registries from Algeria, China, Costa Rica, Cuba, India, the Philippines, and Thailand are collaborating with the International Agency for Research on Cancer in a study of cancer survival in developing countries. Comparisons with the SEER program results of the National Cancer Institute in the United States, and the EUROCARE study of survival in European countries revealed considerable differences in the survival of patients with certain tumors associated with intensive chemotherapeutic treatment regimes (Hodgkin's disease and testicular tumors), more modest differences in the survival of patients with tumors for which early diagnosis and treatment confer an improved prognosis (carcinomas of the large bowel, breast, and cervix), and only slight differences for tumors associated with poor prognosis (carcinomas of the stomach, pancreas, and lung). With limited resources to meet the challenge of the increasing incidence of cancer expected in the next few decades, health authorities in developing countries should be aware of the importance of investing in a range of cancer control activities, including primary prevention and early detection programs as well as treatment.

  5. Survival and Passage of Yearling and Subyearling Chinook Salmon and Juvenile Steelhead at McNary Dam, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, James S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weiland, Mark A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Woodley, Christa M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ploskey, Gene R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carpenter, Scott M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hennen, Matthew J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fischer, Eric S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Batton, George [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carlson, Thomas J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cushing, Aaron W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Zhiqun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Etherington, D. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fu, Tao [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Greiner, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ingraham, John M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kim, Jin A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Xi [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Martinez, Jayson J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mitchell, T. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rayamajhi, Bishes [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Seaburg, Adam [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Skalski, J. R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Townsend, Richard L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wagner, Katie A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zimmerman, Shon A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-12-23

    The study was designed to evaluate the passage and survival of yearling and subyearling Chinook salmon and juvenile steelhead at McNary Dam as stipulated by the 2008 Biological Opinion and Fish Accords and to assess performance measures including route-specific fish passage proportions, travel times, and survival based upon a virtual/paired-release model. This study supports the USACE’s continual effort to improve conditions for juvenile anadromous fish passing through Columbia River dams.

  6. Tracking progress towards equitable child survival in a Nicaraguan community: neonatal mortality challenges to meet the MDG 4

    Directory of Open Access Journals (Sweden)

    Persson Lars-Åke

    2011-06-01

    Full Text Available Abstract Background Nicaragua has made progress in the reduction of the under-five mortality since 1980s. Data for the national trends indicate that this poor Central American country is on track to reach the Millennium Development Goal-4 by 2015. Despite this progress, neonatal mortality has not showed same progress. The aim of this study is to analyse trends and social differentials in neonatal and under-five mortality in a Nicaraguan community from 1970 to 2005. Methods Two linked community-based reproductive surveys in 1993 and 2002 followed by a health and demographic surveillance system providing information on all births and child deaths in urban and rural areas of León municipality, Nicaragua. A total of 49 972 live births were registered. Results A rapid reduction in under-five mortality was observed during the late 1970s (from 103 deaths/1000 live births and the 1980s, followed by a gradual decline to the level of 23 deaths/1000 live births in 2005. This community is on track for the Millennium Development Goal 4 for improved child survival. However, neonatal mortality increased lately in spite of a good coverage of skilled assistance at delivery. After some years in the 1990s with a very small gap in neonatal survival between children of mothers of different educational levels this divide is increasing. Conclusions After the reduction of high under-five mortality that coincided with improved equity in survival in this Nicaraguan community, the current challenge is the neonatal mortality where questions of an equitable perinatal care of good quality must be addressed.

  7. Retail Bank Interest Rate Pass-Through; Is Chile Atypical?

    OpenAIRE

    Alessandro Rebucci; Marco A Espinosa-Vega

    2003-01-01

    This paper investigates empirically the pass-through of money market interest rates to retail banking interest rates in Chile, the United States, Canada, Australia, New Zealand, and five European countries. Overall, Chile's pass-through does not appear atypical. Based on a standard error-correction model, we find that, as in most countries considered, Chile's measured pass-through is incomplete. But Chile's pass-through is also faster than in many other countries considered and is comparable ...

  8. North Texas Sediment Budget: Sabine Pass to San Luis Pass

    Science.gov (United States)

    2006-09-01

    concrete units have been placed over sand-filled fabric tube . .......................................33 Figure 28. Sand-filled fabric tubes protecting...system UTM Zone 15, NAD 83 Longshore drift directions King (in preparation) Based on wave hindcast statistics and limited buoy data Rollover Pass...along with descriptions of the jetties and limited geographic coordinate data1 (Figure 18). The original velum or Mylar sheets from which the report

  9. When will I succeed in my first-year diploma? Survival analysis in Dutch higher education

    NARCIS (Netherlands)

    Bruinsma, Marjon; Jansen, Ellen P. W. A.

    2009-01-01

    The goal of this study was to illustrate survival analysis with higher education data and gain insight into a limited set of factors that predict when students passed their first-year examination at a Dutch university. Study participants consisted of 565 first-year students in four departments. Data

  10. Analysis of Biomechanical Structure and Passing Techniques in Basketball

    Directory of Open Access Journals (Sweden)

    Ricardo E. Izzo

    2011-06-01

    Full Text Available The basketball is a complex sport, which these days has become increasingly linked to its’ psychophysical aspects rather than to the technical ones. Therefore, it is important to make a through study of the passing techniques from the point of view of the type of the pass and its’ biomechanics. From the point of view of the type of the used passes, the most used is the two-handed chest pass with a frequency of 39.9%. This is followed, in terms of frequency, by one-handed passes – the baseball, with 20.9 % – and by the two-handed over the head pass, with 18.2 %, and finally, one- or two-handed indirect passes (bounces, with 11.2 % and 9.8 %. Considering the most used pass in basketball, from the biomechanical point of view, the muscles involved in the correct movement consider all the muscles of the upper extremity, adding also the shoulder muscles as well as the body fixators (abdominals, hip flexors, knee extensors, and dorsal flexors of the foot. The technical and conditional analysis considers the throwing speed, the throw height and the air resistance. In conclusion, the aim of this study is to give some guidelines to improve the mechanical execution of the movements in training, without neglecting the importance of the harmony of the movements themselves.

  11. Genetic susceptibility to and presence of endogenous avian leukosis viruses impose no significant impact on survival days of chickens challenged with very virulent plus Marek's disease virus

    Science.gov (United States)

    Chicks of distinct genotypes at the tumor virus B locus (TVB) in combination with presence or absence of endogenous avian leukosis virus ev21 gene in their genomes were examined for survival day patterns after challenge with very virulent plus Marek’s disease virus (vv+MDV) in three consecutive tria...

  12. Study of the characteristics of forced homogeneous turbulence using band-pass Fourier filtering

    Energy Technology Data Exchange (ETDEWEB)

    Kareem, Waleed Abdel [Suez Canal University, Suez (Egypt)

    2012-03-15

    Simulations of forced homogeneous isotropic turbulence with resolutions of 128{sup 3} and 256{sup 3} using the Lattice Boltzmann method are carried out. The multi-scale vortical structures are identified using the band-pass Fourier cutoff filtering. Three fields at each simulation are extracted and their characteristics are studied. The vortical structures are visualized using the Q-identification method. A new lattice segmentation scheme to identify the central axes of the vortical structures is introduced. The central points of each vortex are identified and they are connected using the direction cosines technique. Results show that the Q-spectrum of the fine scale field survives at low and high wave-numbers. However, the large and intermediate Q-spectra survives till wave-numbers less than or equal to twice the used velocity cutoff wave-numbers. It is found that the extracted central axes clearly resemble the corresponding vortical structures at each scale. Using the central axes scheme, the radii and lengths of the vortical structures at each scale are determined and compared. It is also found that the radii of the identified vortical structures at each scale in both simulations are of the order of several times the Kolmogorov microscales.

  13. Migratory Behavior and Survival of Juvenile Salmonids in the Lower Columbia River and Estuary in 2009

    Energy Technology Data Exchange (ETDEWEB)

    McMichael, Geoffrey A.; Harnish, Ryan A.; Bellgraph, Brian J.; Carter, Jessica A.; Ham, Kenneth D.; Titzler, P. Scott; Hughes, Michael S.

    2010-08-01

    The study reported herein was funded as part of the Anadromous Fish Evaluation Program, which is managed by the U.S. Army Corps of Engineers (USACE). The Anadromous Fish Evaluation Program study code is EST P 02 01: A Study of Salmonid Survival and Behavior through the Columbia River Estuary Using Acoustic Tags. The study was conducted by the Pacific Northwest National Laboratory (PNNL) and National Oceanic and Atmospheric Administration (NOAA) Fisheries for the USACE Portland District. Estimated survival of acoustic-tagged juvenile Chinook salmon and steelhead through the lower Columbia River and estuary in 2009 was lowest in the final 50 km of the estuary. Probability of survival was relatively high (>0.90) for yearling and subyearling Chinook salmon from the Bonneville Dam forebay (rkm 236) to Three-tree Point (rkm 49.6). Survival of juvenile Chinook salmon declined sharply through the lower 50 km of the estuary. Acoustic-tagged steelhead smolts did not survive as well as juvenile Chinook salmon between Bonneville Dam and the mouth of the Columbia River. Steelhead survival began to decline farther upstream (at rkm 86) relative to that of the Chinook salmon stocks. Subyearling Chinook salmon survival decreased markedly as the season progressed. It remains to be determined whether later migrating subyearling Chinook salmon are suffering increasing mortality as the season progresses or whether some portion of the apparent loss is due to fish extending their freshwater residence. This study provided the first glimpse into what promises to be a very informative way to learn more about how juvenile salmonid passage experiences through the FCRPS may influence their subsequent survival after passing Bonneville Dam. New information regarding the influence of migration pathway through the lower 50 km of the Columbia River estuary on probability of survival of juvenile salmonids, combined with increased understanding regarding the foraging distances and time periods of

  14. Mouse myocardial first-pass perfusion MR imaging

    NARCIS (Netherlands)

    Coolen, Bram F.; Moonen, Rik P. M.; Paulis, Leonie E. M.; Geelen, Tessa; Nicolay, Klaas; Strijkers, Gustav J.

    2010-01-01

    A first-pass myocardial perfusion sequence for mouse cardiac MRI is presented. A segmented ECG-triggered acquisition combined with parallel imaging acceleration was used to capture the first pass of a Gd-DTPA bolus through the mouse heart with a temporal resolution of 300-400 msec. The method was

  15. Mouse myocardial first-pass perfusion MR imaging

    NARCIS (Netherlands)

    Coolen, B.F.; Moonen, R.P.M.; Paulis, L.E.M.; Geelen, T.; Nicolay, K.; Strijkers, G.J.

    2010-01-01

    A first-pass myocardial perfusion sequence for mouse cardiac MRI is presented. A segmented ECG-triggered acquisition combined with parallel imaging acceleration was used to capture the first pass of a Gd-DTPA bolus through the mouse heart with a temporal resolution of 300–400 msec. The method was

  16. 12 CFR 560.32 - Pass-through investments.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Pass-through investments. 560.32 Section 560.32 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY LENDING AND INVESTMENT Lending and Investment Powers for Federal Savings Associations § 560.32 Pass-through investments. (a) A...

  17. Dietary Administration of Yeast β 1,3 1,6 Glucan on Immunity and Survival Rate of White Indian Shrimp, Fennerpenaeus indicus Challenged with White Spot Syndrome Disease

    Directory of Open Access Journals (Sweden)

    Babak Ghaednia

    2012-01-01

    Full Text Available The potency of dietary β 1,3 1,6 glucan (BG, derived from Saccharomyces cerevisiae, in stimulating the non-specific immunity of white Indian shrimp, Fennerpenaeus indicus (Milne-Edwards, 1837 and improving its resistance to white spot syndrome disease were investigated. F. indicus (11.32±1.20 g were fed for 20 days on a series of treatment diets containing graded levels of BG (blank control, 0 as control, 2, 10, 20 g kg-1 feed and were then challenged by injection of WSSV virus. Total haemocyte count (THC, total plasma protein (TPP, phagocytic activity (PA and Bacterial Clearance activity (BC were measured at days 0, 7, 14, 21 after BG feeding, and shrimp survival rate was also recorded daily after challenge. THC, TPP, PA and BC of the 10 and 20 g kg-1 BG treatments were significantly higher (P<0.05 by day 14 than control and 2 g kg-1 treatment shrimp. Survival rate of shrimp fed with the diet containing 10 and 20 g kg-1 BG after 21 days, were 53.32±5.77 and 48.32±5.77%, respectively. Accordingly, oral administration of BG at an optimal level of 10 g kg-1 diet for 20 days efficaciously stimulate the immune defense and improve the survival rate of WSV-infected F. indicus.

  18. Pass-Through to Import Prices: Evidence from Developing Countries

    OpenAIRE

    Miguel Fuentes

    2007-01-01

    In this paper I study the pass-through of nominal exchange rate changes to the price of imported goods in four developing countries. The results indicate that 75% of changes in the exchange rate are passed-through to the domestic currency price of imported goods within one quarter. Complete pass-through is attained within one year. There is no evidence that exchange rate pass-through to the price of imported goods has declined over time even in those countries that have managed to reduce infl...

  19. Maximum Neutral Buoyancy Depth of Juvenile Chinook Salmon: Implications for Survival during Hydroturbine Passage

    Energy Technology Data Exchange (ETDEWEB)

    Pflugrath, Brett D.; Brown, Richard S.; Carlson, Thomas J.

    2012-03-01

    This study investigated the maximum depth at which juvenile Chinook salmon Oncorhynchus tshawytscha can acclimate by attaining neutral buoyancy. Depth of neutral buoyancy is dependent upon the volume of gas within the swim bladder, which greatly influences the occurrence of injuries to fish passing through hydroturbines. We used two methods to obtain maximum swim bladder volumes that were transformed into depth estimations - the increased excess mass test (IEMT) and the swim bladder rupture test (SBRT). In the IEMT, weights were surgically added to the fishes exterior, requiring the fish to increase swim bladder volume in order to remain neutrally buoyant. SBRT entailed removing and artificially increasing swim bladder volume through decompression. From these tests, we estimate the maximum acclimation depth for juvenile Chinook salmon is a median of 6.7m (range = 4.6-11.6 m). These findings have important implications to survival estimates, studies using tags, hydropower operations, and survival of juvenile salmon that pass through large Kaplan turbines typical of those found within the Columbia and Snake River hydropower system.

  20. 36 CFR 13.918 - Sable Pass Wildlife Viewing Area.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Sable Pass Wildlife Viewing... Preserve General Provisions § 13.918 Sable Pass Wildlife Viewing Area. (a) Entry into the Sable Pass Wildlife Viewing Area is prohibited from May 1 to September 30 unless authorized by the Superintendent. (b...

  1. Time-varying exchange rate pass-through: experiences of some industrial countries

    OpenAIRE

    Toshitaka Sekine

    2006-01-01

    This paper estimates exchange rate pass-through of six major industrial countries using a time-varying parameter with stochastic volatility model. Exchange rate pass-through is divided into impacts of exchange rate fluctuations to import prices (first-stage pass-through) and those of import price movements to consumer prices (second-stage pass-through). The paper finds that both stages of pass-through have declined over time for all the sample countries. The decline in second-stage pass-throu...

  2. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2002-01-01

    We present a new transformation of call-by-value lambdaterms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Because it operates in one pass, it directly yields compact CPS programs that are comparable to what one would...... write by hand. Because it is compositional, it allows proofs by structural induction. Because it is first-order, reasoning about it does not require the use of a logical relation. This new CPS transformation connects two separate lines of research. It has already been used to state a new and simpler...... correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  3. DC-pass filter design with notch filters superposition for CPW rectenna at low power level

    Science.gov (United States)

    Rivière, J.; Douyère, A.; Alicalapa, F.; Luk, J.-D. Lan Sun

    2016-03-01

    In this paper the challenging coplanar waveguide direct current (DC) pass filter is designed, analysed, fabricated and measured. As the ground plane and the conductive line are etched on the same plane, this technology allows the connection of series and shunt elements to the active devices without via holes through the substrate. Indeed, this study presents the first step in the optimization of a complete rectenna in coplanar waveguide (CPW) technology: key element of a radio frequency (RF) energy harvesting system. The measurement of the proposed filter shows good performance in the rejection of F0=2.45 GHz and F1=4.9 GHz. Additionally, a harmonic balance (HB) simulation of the complete rectenna is performed and shows a maximum RF-to-DC conversion efficiency of 37% with the studied DC-pass filter for an input power of 10 µW at 2.45 GHz.

  4. Survival Estimates for the Passage of Juvenile Salmonids through Snake River Dams and Reservoirs, 1994 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Muir, William D.

    1995-02-01

    In 1994, the National Marine Fisheries Service and the University of Washington completed the second year of a multi-year study to estimate survival of juvenile salmonids (Oncorhynchus spp.) passing through the dams and reservoirs of the Snake River. Actively migrating smolts were collected at selected locations above, at, and below Lower Granite Dam, tagged with passive integrated transponder (PIT) tags, and released to continue their downstream migration. Survival estimates were calculated using the Single-Release, Modified Single-Release, and Paired-Release Models.

  5. A message-passing approach to random constraint satisfaction problems with growing domains

    International Nuclear Information System (INIS)

    Zhao, Chunyan; Zheng, Zhiming; Zhou, Haijun; Xu, Ke

    2011-01-01

    Message-passing algorithms based on belief propagation (BP) are implemented on a random constraint satisfaction problem (CSP) referred to as model RB, which is a prototype of hard random CSPs with growing domain size. In model RB, the number of candidate discrete values (the domain size) of each variable increases polynomially with the variable number N of the problem formula. Although the satisfiability threshold of model RB is exactly known, finding solutions for a single problem formula is quite challenging and attempts have been limited to cases of N ∼ 10 2 . In this paper, we propose two different kinds of message-passing algorithms guided by BP for this problem. Numerical simulations demonstrate that these algorithms allow us to find a solution for random formulas of model RB with constraint tightness slightly less than p cr , the threshold value for the satisfiability phase transition. To evaluate the performance of these algorithms, we also provide a local search algorithm (random walk) as a comparison. Besides this, the simulated time dependence of the problem size N and the entropy of the variables for growing domain size are discussed

  6. Attributes of Candidates Passing the ABS Certifying Examination on the First Attempt-Program Directors׳ Perspective.

    Science.gov (United States)

    Sheikh, Mohd Raashid; Hulme, Michael

    2016-01-01

    The American Board of Surgery Certifying Examination (CE) is a pivotal event in a surgeon's career development, as it is the last challenge before achieving Board certification. First-time pass rate on the CE is one of the key metrics of surgery residency programs. The overall pass rate on the CE has declined significantly in recent years. The goal of this study was the identification of attributes of general surgery residents that are associated with passing the CE at the first attempt. The modified Delphi process was used to survey general surgery program directors. The study was conducted in 2 rounds in the interest of time available for surgical education research fellowship project. All 259 program directors were contacted in each round of surveys. In all, 49 (19%) responded to the first round and 54 (21%) responded to the second round of survey. The characteristics of a successful resident on CE include confidence, self-motivation, sound knowledge base, strong performance on the Board's training examination (American Board of Surgery In-Training Examination), and mock orals, and good communication skills. Postgraduate years 4 and 5 are the most likely resident levels at which failure could be predicted. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  7. Integrated Cu-based TM-pass polarizer using CMOS technology platform

    KAUST Repository

    Ng, Tien Khee; Khan, Mohammed Zahed Mustafa; Ooi, Boon S.

    2010-01-01

    A transverse-magnetic-pass (TM-pass) copper (Cu) polarizer is proposed and analyzed using the previously published two-dimensional Method-of-Lines beam-propagation model. The proposed polarizer exhibits a simulated high-pass filter characteristics

  8. Relation of intracellular cyclic AMP to the shape of mammalian cell survival curves

    International Nuclear Information System (INIS)

    Lehnert, S.

    1975-01-01

    Results of experiments with V79 cells growing in tissue culture indicate that the reproductive survival of cells following irradiation is influenced by the level of intracellular 3', 5'-cyclic adenosine monophosphate (cyclic AMP) at the time of irradiation. Cells containing high levels of cyclic AMP induced by treatments with drugs show a characteristic survival curve in which the extent of the shoulder is increased so that the survival after low doses is enhanced. The exponential slope or D 0 , however, is decreased so that at high doses the survival of cells containing high levels of cyclic AMP may be less than that of controls. Naturally occurring changes in radiosensitivity such as those observed as cells pass through the division cycle, may also be related to parallel changes in cyclic AMP concentration occurring during the cycle. Injection of mice with compounds producing elevated cyclic AMP prior to whole-body irradiation increases survival at seven days post-irradiation. The shape of the survival curve for intestinal stem cells in these mice differs from that of the control in having an increased extrapolation number; no change in D 0 is observed in this in vivo situation. (author)

  9. Double-pass quantum volume hologram

    International Nuclear Information System (INIS)

    Vasilyev, Denis V.; Sokolov, Ivan V.

    2011-01-01

    We propose a scheme for parallel, spatially multimode quantum memory for light. The scheme is based on the propagation in different directions of a quantum signal wave and strong classical reference wave, like in a classical volume hologram and the previously proposed quantum volume hologram [D. V. Vasilyev et al., Phys. Rev. A 81, 020302(R) (2010)]. The medium for the hologram consists of a spatially extended ensemble of cold spin-polarized atoms. In the absence of the collective spin rotation during the interaction, two passes of light for both storage and retrieval are required, and therefore the present scheme can be called a double-pass quantum volume hologram. The scheme is less sensitive to diffraction and therefore is capable of achieving a higher density of storage of spatial modes as compared to the previously proposed thin quantum hologram [D. V. Vasilyev et al., Phys. Rev. A 77, 020302(R) (2008)], which also requires two passes of light for both storage and retrieval. However, the present scheme allows one to achieve a good memory performance with a lower optical depth of the atomic sample as compared to the quantum volume hologram. A quantum hologram capable of storing entangled images can become an important ingredient in quantum information processing and quantum imaging.

  10. Notes on basis band-pass circuits; Notes sur les circuits de base passe-bande

    Energy Technology Data Exchange (ETDEWEB)

    Ailloud, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-07-01

    Resistor load amplifier stages, basic band-pass RC networks, conventional single-tuned circuits, have the same transfer function. Common properties and differences because diverse magnitude of parameters with proposed problems are exposed. Next the case of several cascaded stages (or networks) is examined when there is no reaction ones to another. (author) [French] Les etages amplificateurs a resistances, les circuits passe-bande RC elementaires, le circuit resonnant classique possedent la meme fonction de transfert. On fait ressortir les proprietes communes et les differences de comportement dues aux ordres de grandeur qu'il est possible de donner aux parametres en fonction des problemes a resoudre. On examine ensuite le cas de plusieurs etages (ou de plusieurs circuits) en cascade lorsqu'ils ne reagissent pas les uns sur les autres. (auteur)

  11. Modeling drivers' passing duration and distance in a virtual environment

    Directory of Open Access Journals (Sweden)

    Haneen Farah

    2013-07-01

    The main contribution of this paper is in the empirical models developed for passing duration and distance which highlights the factors that affect drivers' passing behavior and can be used to enhance the passing models in simulation programs.

  12. Survival tactics within thermally-challenging roosts: heat tolerance ...

    African Journals Online (AJOL)

    Microclimates were thermally challenging, being very hot (>40°C) for several hours daily in summer and autumn, and cold (<10°C) for much of the night in winter Thermal preference tests revealed that the bats actively selected temperature zones (35°- 42°C) in which basal metabolic rate could be maintained, and above the ...

  13. BRAZILIAN EDUCATION AND SURVIVAL STRATEGIES OF CAPITALISM

    Directory of Open Access Journals (Sweden)

    Adriana Almeida Sales de Melo

    2012-06-01

    Full Text Available In discussing the theme Imperialism, Crisis and education, the essay points out aspects of our historical totality in relation to recent crises through which it passed capitalism, and its relationship to changes in Brazilian educational policies. Education remains at the heart of development projects, as a producer of knowledge, as well as guiding the processes of social conformation. They also discussed the aftermath of the crisis: the rise of social inequality and the increase of labor exploitation. Make clear our project of society and education, as resistance movements to the survival of capitalism is a necessity in building movements of counter-hegemony.

  14. Estimating the Exchange Rate Pass-Through to Prices in Mexico

    OpenAIRE

    Josué Fernando Cortés Espada

    2013-01-01

    This paper estimates the magnitude of the exchange rate pass-through to consumer prices in Mexico. Moreover, it analyzes if the pass-through dynamics have changed in recent years. In particular, it uses a methodology that generates results consistent with the hierarchy implicit in the cpi. The results suggest that the exchange rate pass-through to the general price level is low and not statistically significant. However, the pass-through is positive and significant for goods prices. Furthermo...

  15. Teaching Strategies for the Forearm Pass in Volleyball

    Science.gov (United States)

    Casebolt, Kevin; Zhang, Peng; Brett, Christine

    2014-01-01

    This article shares teaching strategies for the forearm pass in the game of volleyball and identifies how they will help students improve their performance and development of forearm passing skills. The article also provides an assessment rubric to facilitate student understanding of the skill.

  16. Calculation of trajectory parameters of long pass in basketball.

    Directory of Open Access Journals (Sweden)

    Charikova K.M.

    2011-08-01

    Full Text Available Values of a ball's flight trajectory parameters depending on a distance of long pass, a corner of a ball's start and height of a throwing point are submitted in article. Coordinates of reference points installation for training to long pass with an optimum trajectory of a ball's flight are designed. Requirements to simulators design are determined. Corners of ball's long pass performance in various game situations are recommended.

  17. ICRF heating of passing ions in TMX-U

    International Nuclear Information System (INIS)

    Molvik, A.W.; Dimonte, G.; Barter, J.; Campbell, R.; Cummins, W.F.; Falabella, S.; Ferguson, S.W.; Poulsen, P.

    1986-04-01

    By placing ion-cyclotron resonant frequency (ICRF) antennas on both sides of a midplane gas-feed system in the central cell of the Tandem Mirror Experiment-Upgrade (TMX-U), our results have improved in the following areas: (a) The end losses out both ends show a factor of 3 to 4 increase in passing-ion temperatures and a factor of 2 to 3 decrease in passing-ion densities. (b) The passing-ion heating is consistent with Monte Carlo predictions. (c) The plasma density can be sustained by ICRF plus gas fueling as observed on other experiments

  18. An empirical study of exchange rate pass-through in China

    Directory of Open Access Journals (Sweden)

    Jin Xiaowen

    2012-01-01

    Full Text Available This paper seeks to estimate exchange rate pass-through in China and investigate its relationship with monetary policy. Linear and VAR models are applied to analyze robustness. The linear model shows that, over the long run, a 1% appreciation of NEER causes a decline in the CPI inflation rate of 0.132% and PPI inflation rate of 0.495%. The VAR model supports the results of the linear model, suggesting a fairly low CPI pass-through and relatively higher PPI pass-through. Furthermore, this paper finds that, with the fixed exchange rate regime, CPI pass-through remains higher. The exchange rate regimes influence on CPI pass through, combined with the fact that appreciation diminishes inflation, suggests that the Chinese government could pursue a more flexible exchange rate policy. In addition, reasons for low exchange rate pass-through for CPI are analyzed. The analysis considers price control, basket and weight of Chinese price indices, distribution cost, and imported and non-tradable share of inputs.

  19. Inclusive Education in Thailand: Practices and Challenges

    Science.gov (United States)

    Vorapanya, Sermsap; Dunlap, Diane

    2014-01-01

    In 2008, Thailand passed legislation on the educational provisions for students with disabilities to mandate the implementation of inclusive education. This article provides a historical overview of special education in Thailand and the emergence of inclusive education as it moves from policy to practice. To further identify the challenges faced…

  20. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2001-01-01

    We present a new transformation of λ-terms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Previous CPS transformations only enjoyed two out of the three properties of being first-order, one-pass, and compositional......, but the new transformation enjoys all three properties. It is proved correct directly by structural induction over source terms instead of indirectly with a colon translation, as in Plotkin's original proof. Similarly, it makes it possible to reason about CPS-transformed terms by structural induction over...... source terms, directly.The new CPS transformation connects separately published approaches to the CPS transformation. It has already been used to state a new and simpler correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  1. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2003-01-01

    We present a new transformation of λ-terms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Previous CPS transformations only enjoyed two out of the three properties of being first-order, one-pass, and compositional......, but the new transformation enjoys all three properties. It is proved correct directly by structural induction over source terms instead of indirectly with a colon translation, as in Plotkin's original proof. Similarly, it makes it possible to reason about CPS-transformed terms by structural induction over...... source terms, directly.The new CPS transformation connects separately published approaches to the CPS transformation. It has already been used to state a new and simpler correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  2. Improving fish survival through turbines

    International Nuclear Information System (INIS)

    Ferguson, J.W.

    1993-01-01

    Much of what is known about fish passage through hydroturbines has been developed by studying migratory species of fish passing through large Kaplan turbine units. A review of the literature on previous fish passage research presented in the accompanying story illustrates that studies have focused on determining mortality levels, rather than identifying the causal mechanism involved. There is a need for understanding how turbine designs could be altered to improve fish passage conditions, how to retrofit existing units, and how proposed hydro plant operational changes may affect fish survival. The US Army Corps of Engineers has developed a research program to define biologically based engineering criteria for improving fish passage conditions. Turbine designs incorporating these criteria can be evaluated for their effects on fish survival, engineering issues, costs, and power production. The research program has the following objectives: To gain a thorough knowledge of the mechanisms of fish mortality; To define the biological sensitivities of key fish species to these mechanisms of mortality; To develop new turbine design criteria to reduce fish mortality; To construct prototype turbine designs, and to test these designs for fish passage, hydro-mechanical operation, and power production; and To identify construction and power costs associated with new turbine designs

  3. Static thermo-optic instability in double-pass fiber amplifiers

    DEFF Research Database (Denmark)

    Lægsgaard, Jesper

    2016-01-01

    A coupled-mode formalism, earlier used to describe transverse mode instabilities in single-pass optical fiber amplifiers, is extended to the case of double-pass amplifiers. Contrary to the single-pass case, it is shown that the thermo-optic nonlinearity can couple light at the same frequency...... between the LP01 and LP11 modes, leading to a static deformation of the output beam profile. This novel phenomenon is caused by the interaction of light propagating in either direction with thermo-optic index perturbations caused by light propagating in the opposite direction. The threshold power...... for the static deformation is found to be several times lower than what is typically found for the dynamic modal instabilities observed in single-pass amplifiers. (C) 2016 Optical Society of America...

  4. Effect of passing vessels on a moored ship

    Energy Technology Data Exchange (ETDEWEB)

    Lean, G H; Price, W A

    1977-11-01

    The effect of passing vessels on a moored ship was investigated by a series of model tests carried out at the Hydraulics Research Station for the Esso Petroleum Co. Ltd., transportation department in connection with their oil jetty at Milford Haven. A main conclusion was that the forces appeared to be due to the pressure gradients associated with the pattern of flow that accompanies the passing ship rather than with the wave system. Slack lines are to be avoided, and some relief in maximum line loads can be achieved by increasing the pretension. The results included the effects of passing vessel speed and ship clearance and draft.

  5. The Pass-Through of Exchange Rate Changes to Import Prices

    OpenAIRE

    Ketelsen, Uwe; Kortelainen, Mika

    1996-01-01

    In this paper we analyze the empirical relevance of exchange rate pass-through for Finland, Sweden and Denmark during the period 1980–1994. Further, we attempt to determine if there has been a structural change in the pass-through relationship in the1990s. We find that about half the changes in exchange rates and world prices are passed through to import prices within one year, and three-quarters of such changes are passed through to import prices in two years. Moreover, there are no major di...

  6. TRT Barrel milestones passed

    CERN Multimedia

    Ogren, H

    2004-01-01

    The barrel TRT detector passed three significant milestones this spring. The Barrel Support Structure (BSS) was completed and moved to the SR-1 building on February 24th. On March 12th the first module passed the quality assurance testing in Building 154 and was transported to the assembly site in the SR-1 building for barrel assembly. Then on April 21st the final production module that had been scanned at Hampton University was shipped to CERN. TRT Barrel Module Production The production of the full complement of barrel modules (96 plus 9 total spares) is now complete. This has been a five-year effort by Duke University, Hampton University, and Indiana University. Actual construction of the modules in the United States was completed in the first part of 2004. The production crews at each of the sites in the United States have now completed their missions. They are shown in the following pictures. Duke University: Production crew with the final completed module. Indiana University: Module producti...

  7. PASS Student Leader and Mentor Roles: A Tertiary Leadership Pathway

    Science.gov (United States)

    Skalicky, Jane; Caney, Annaliese

    2010-01-01

    In relation to developing leadership skills during tertiary studies, this paper considers the leadership pathway afforded by a Peer Assisted Study Sessions (PASS) program which includes the traditional PASS Leader role and a more senior PASS Mentor role. Data was collected using a structured survey with open-ended questions designed to capture the…

  8. Regenerative beam breakup in multi-pass electron accelerators

    International Nuclear Information System (INIS)

    Vetter, A.M. Jr.

    1980-01-01

    Important electron coincidence experiments in the 1 to 2 GeV range require electron beams of high intensity and high duty factor. To provide such beams, multi-pass electron accelerator systems are being developed at many laboratories. The beam current in multi-pass electron machines is limited by bean breakup which arises from interaction of the electron beam with deflection modes of the accelerator structure. Achieving high beam intensity (50 to 100 μA) will require detailed understanding and careful control of beam breakup phenomena, and is the subject of this thesis. The TM 11 -like traveling wave theory is applied to obtain a physical understanding of beam-mode interactions and the principles of focussing in simple two-pass systems, and is used as a basis for general studies of the dependence of starting current on accelerator parameters in systems of many passes. The concepts developed are applied in analyzing beam breakup in the superconducting recyclotron at Stanford. Measurements of beam interactions with selected breakup modes are incorporated in a simple model in order to estimate relative strengths of breakup modes and to predict starting currents in five-pass operation. The improvement over these predicted currents required in order to obtain 50 to 100 μA beams is shown to be achievable with a combination of increased breakup mode loading and improved beam optics

  9. Statistics of Epidemics in Networks by Passing Messages

    Science.gov (United States)

    Shrestha, Munik Kumar

    Epidemic processes are common out-of-equilibrium phenomena of broad interdisciplinary interest. In this thesis, we show how message-passing approach can be a helpful tool for simulating epidemic models in disordered medium like networks, and in particular for estimating the probability that a given node will become infectious at a particular time. The sort of dynamics we consider are stochastic, where randomness can arise from the stochastic events or from the randomness of network structures. As in belief propagation, variables or messages in message-passing approach are defined on the directed edges of a network. However, unlike belief propagation, where the posterior distributions are updated according to Bayes' rule, in message-passing approach we write differential equations for the messages over time. It takes correlations between neighboring nodes into account while preventing causal signals from backtracking to their immediate source, and thus avoids "echo chamber effects" where a pair of adjacent nodes each amplify the probability that the other is infectious. In our first results, we develop a message-passing approach to threshold models of behavior popular in sociology. These are models, first proposed by Granovetter, where individuals have to hear about a trend or behavior from some number of neighbors before adopting it themselves. In thermodynamic limit of large random networks, we provide an exact analytic scheme while calculating the time dependence of the probabilities and thus learning about the whole dynamics of bootstrap percolation, which is a simple model known in statistical physics for exhibiting discontinuous phase transition. As an application, we apply a similar model to financial networks, studying when bankruptcies spread due to the sudden devaluation of shared assets in overlapping portfolios. We predict that although diversification may be good for individual institutions, it can create dangerous systemic effects, and as a result

  10. Optimal Cluster Mill Pass Scheduling With an Accurate and Rapid New Strip Crown Model

    International Nuclear Information System (INIS)

    Malik, Arif S.; Grandhi, Ramana V.; Zipf, Mark E.

    2007-01-01

    Besides the requirement to roll coiled sheet at high levels of productivity, the optimal pass scheduling of cluster-type reversing cold mills presents the added challenge of assigning mill parameters that facilitate the best possible strip flatness. The pressures of intense global competition, and the requirements for increasingly thinner, higher quality specialty sheet products that are more difficult to roll, continue to force metal producers to commission innovative flatness-control technologies. This means that during the on-line computerized set-up of rolling mills, the mathematical model should not only determine the minimum total number of passes and maximum rolling speed, it should simultaneously optimize the pass-schedule so that desired flatness is assured, either by manual or automated means. In many cases today, however, on-line prediction of strip crown and corresponding flatness for the complex cluster-type rolling mills is typically addressed either by trial and error, by approximate deflection models for equivalent vertical roll-stacks, or by non-physical pattern recognition style models. The abundance of the aforementioned methods is largely due to the complexity of cluster-type mill configurations and the lack of deflection models with sufficient accuracy and speed for on-line use. Without adequate assignment of the pass-schedule set-up parameters, it may be difficult or impossible to achieve the required strip flatness. In this paper, we demonstrate optimization of cluster mill pass-schedules using a new accurate and rapid strip crown model. This pass-schedule optimization includes computations of the predicted strip thickness profile to validate mathematical constraints. In contrast to many of the existing methods for on-line prediction of strip crown and flatness on cluster mills, the demonstrated method requires minimal prior tuning and no extensive training with collected mill data. To rapidly and accurately solve the multi-contact problem

  11. Small Numbers, Big Challenges: Adolescent and Young Adult Cancer Incidence and Survival in New Zealand.

    Science.gov (United States)

    Ballantine, Kirsten R; Watson, Heidi; Macfarlane, Scott; Winstanley, Mark; Corbett, Robin P; Spearing, Ruth; Stevanovic, Vladimir; Yi, Ma; Sullivan, Michael J

    2017-06-01

    This study was undertaken to determine cancer survival and describe the unique spectrum of cancers diagnosed among New Zealand's adolescents and young adult (AYA) population. Registrations for 1606 15-24 year olds diagnosed with a new primary malignant tumor between 2000 and 2009 were obtained from the New Zealand Cancer Registry and classified according to AYA diagnostic group and subgroup, age, sex, and prioritized ethnicity. Age-standardized incidence rates (IRs) per million person years and 5-year relative survival ratios were calculated. Cancer incidence was 228.6 per million for adolescents aged 15-19 years and 325.7 per million for young adults aged 20-24 years. Overall IRs were consistent across all ethnic groups but there were unique ethnic differences by tumor group including a higher incidence of bone tumors, carcinoma of the gastrointestinal tract, and gonadal germ cell tumors among Maori, a higher incidence of leukemia among Pacific peoples, and a higher incidence of melanoma among non-Maori/non-Pacific peoples. Five-year relative survival for adolescents (75.1%) and AYA overall (80.6%) appeared poorer than had been achieved in other high-income countries. Maori (69.5%) and Pacific (71.3%) AYA had lower 5-year survival compared to non-Maori/non-Pacific peoples (84.2%). The survival disparities observed require further investigation to identify and address the causes of these inferior outcomes. The newly established AYA Cancer Network Aotearoa has been tasked with improving cancer survival and care and ensuring equality of access for New Zealand AYAs with cancer.

  12. Applicability estimation of flowmeter logging for detecting hydraulic pass

    International Nuclear Information System (INIS)

    Miyakawa, Kimio; Tanaka, Yasuji; Tanaka, Kazuhiro

    1997-01-01

    Estimation of the hydraulic pass governing hydrogeological structure contributes significantly to the siting HLW repository. Flowmeter logging can detect hydraulic passes by measuring vertical flow velocity of groundwater in the borehole. We reviewed application of this logging in situ. The hydraulic pass was detected with combination of ambient flow logging, with pumping and/or injecting induced flow logging. This application showed that the flowmeter logging detected hydraulic passes conveniently and accurately compared with other hydraulic tests. Hydraulic conductivity by using flowmeter logging was assessed above 10 -6 m/sec and within one order from comparison with injection packer tests. We suggest that appropriate application of the flowmeter logging for the siting is conducted before hydraulic tests because test sections and monitoring sections are decided rationally for procurement of quantitative hydraulic data. (author)

  13. Integrated Cu-based TM-pass polarizer using CMOS technology platform

    KAUST Repository

    Ng, Tien Khee

    2010-01-01

    A transverse-magnetic-pass (TM-pass) copper (Cu) polarizer is proposed and analyzed using the previously published two-dimensional Method-of-Lines beam-propagation model. The proposed polarizer exhibits a simulated high-pass filter characteristics, with TM0 and TE0 mode transmissivity of >70% and <5%, respectively, in the wavelength regime of 1.2-1.6 μm. The polarization extinction ratio (PER) given by 10 log10 (PTM0)/(PTE0) is +11.5 dB across the high-pass wavelength regime. To the best of the authors\\' knowledge, we report here the smallest footprint CMOS-platform compatible TM-polarizer.

  14. 77 FR 31725 - Safety Zone; Belle Pass Dredge Operations, Belle Pass, Mile Marker 1.0 to Mile Marker (−0.2...

    Science.gov (United States)

    2012-05-30

    ... Environmental Health Risks and Safety Risks. This rule is not an economically significant rule and does not create an environmental risk to health or risk to safety that may disproportionately affect children. 11...-AA00 Safety Zone; Belle Pass Dredge Operations, Belle Pass, Mile Marker 1.0 to Mile Marker (-0.2), Port...

  15. Challenging a dogma: five-year survival does not equal cure in all colorectal cancer patients.

    Science.gov (United States)

    Abdel-Rahman, Omar

    2018-02-01

    The current study tried to evaluate the factors affecting 10- to 20- years' survival among long term survivors (>5 years) of colorectal cancer (CRC). Surveillance, Epidemiology and End Results (SEER) database (1988-2008) was queried through SEER*Stat program.Univariate probability of overall and cancer-specific survival was determined and the difference between groups was examined. Multivariate analysis for factors affecting overall and cancer-specific survival was also conducted. Among node positive patients (Dukes C), 34% of the deaths beyond 5 years can be attributed to CRC; while among M1 patients, 63% of the deaths beyond 5 years can be attributed to CRC. The following factors were predictors of better overall survival in multivariate analysis: younger age, white race (versus black race), female gender, Right colon location (versus rectal location), earlier stage and surgery (P <0.0001 for all parameters). Similarly, the following factors were predictors of better cancer-specific survival in multivariate analysis: younger age, white race (versus black race), female gender, Right colon location (versus left colon and rectal locations), earlier stage and surgery (P <0.0001 for all parameters). Among node positive long-term CRC survivors, more than one third of all deaths can be attributed to CRC.

  16. Growth, nonspecific immune characteristics, and survival upon challenge with Vibrio harveyi in Pacific white shrimp (Litopenaeus vannamei) raised on diets containing algal meal.

    Science.gov (United States)

    Nonwachai, Thasanee; Purivirojkul, Watchariya; Limsuwan, Chalor; Chuchird, Niti; Velasco, Mario; Dhar, Arun K

    2010-08-01

    A 70-day growth trial was conducted with postlarvae 12 (PL12) Pacific white shrimp (Litopenaeus vannamei) to study the suitability of soybean meal and oil originating from a single-celled microorganism (thraustochytrid) as fishmeal and fish oil substitutes in practical diets for L. vannamei. The growth, survival rate and immune characteristics were evaluated. Seven experimental diets were designed with soybean meal used as the primary protein source; each formulation contained 33% crude protein and 8% lipid. Fish oil was completely substituted with 3% soybean oil and meals originating from single-celled heterotrophs rich in docosahexaenoic acid (DHA) and arachidonic acid (ARA) were added at different concentrations. A commercial shrimp feed was used as the control diet. The final weights and survival rates of the shrimp were not significantly different among all treatments. However, shrimp raised on diets supplemented with marine algal meals rich in DHA and ARA showed significant improvement in immune parameters, such as total hemocyte count, phenoloxidase activity, superoxide dismutase activity, and bactericidal activity. Additionally, the survival rate after challenge with Vibrio harveyi was increased. These findings demonstrated that substitution of thraustochytrid-derived meals as an alternative to fish-based ingredients in shrimp diets provided similar growth rates while increasing the immune parameters and providing vibriosis resistance. Copyright 2010 Elsevier Ltd. All rights reserved.

  17. Acoustic Telemetry Studies of Juvenile Chinook Salmon Survival at the Lower Columbia Projects in 2006

    Energy Technology Data Exchange (ETDEWEB)

    Ploskey, Gene R.; Weiland, Mark A.; Hughes, James S.; Zimmerman, Shon A.; Durham, Robin E.; Fischer, Eric S.; Kim, Jina; Townsend, Richard L.; Skalski, John R.; McComas, Roy L.

    2008-02-01

    The Portland District of the U.S. Army Corps of Engineers contracted with the Pacific Northwest National Laboratory (PNNL) to conduct three studies using acoustic telemetry to estimate detection probabilities and survival of juvenile Chinook salmon at three hydropower projects on the lower Columbia River. The primary goals were to estimate detection and survival probabilities based on sampling with JSATS equipment, assess the feasibility of using JSATS for survival studies, and estimate sample sizes needed to obtain a desired level of precision in future studies. The 2006 JSATS arrays usually performed as well or better than radio telemetry arrays in the JDA and TDA tailwaters, and underperformed radio arrays in the BON tailwater, particularly in spring. Most of the probabilities of detection on at least one of all arrays in a tailwater exceeded 80% for each method, which was sufficient to provide confidence in survival estimates. The probability of detection on one of three arrays includes survival and detection probabilities because fish may die or pass all three arrays undetected but alive.

  18. Technological Challenges for High-Brightness Photo-Injectors

    CERN Multimedia

    Suberlucq, Guy

    2004-01-01

    Many applications, from linear colliders to free-electron lasers, passing through light sources and many other electron sources, require high brightness electron beams, usually produced by photo-injectors. Because certain parameters of these applications differ by several orders of magnitude, various solutions were implemented for the design and construction of the three main parts of the photo-injectors: lasers, photocathodes and guns. This paper summarizes the different requirements, how they lead to technological challenges and how R&D programs try to overcome these challenges. Some examples of state-of-the-art parts are presented.

  19. Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data.

    Science.gov (United States)

    Guinney, Justin; Wang, Tao; Laajala, Teemu D; Winner, Kimberly Kanigel; Bare, J Christopher; Neto, Elias Chaibub; Khan, Suleiman A; Peddinti, Gopal; Airola, Antti; Pahikkala, Tapio; Mirtti, Tuomas; Yu, Thomas; Bot, Brian M; Shen, Liji; Abdallah, Kald; Norman, Thea; Friend, Stephen; Stolovitzky, Gustavo; Soule, Howard; Sweeney, Christopher J; Ryan, Charles J; Scher, Howard I; Sartor, Oliver; Xie, Yang; Aittokallio, Tero; Zhou, Fang Liz; Costello, James C

    2017-01-01

    Improvements to prognostic models in metastatic castration-resistant prostate cancer have the potential to augment clinical trial design and guide treatment strategies. In partnership with Project Data Sphere, a not-for-profit initiative allowing data from cancer clinical trials to be shared broadly with researchers, we designed an open-data, crowdsourced, DREAM (Dialogue for Reverse Engineering Assessments and Methods) challenge to not only identify a better prognostic model for prediction of survival in patients with metastatic castration-resistant prostate cancer but also engage a community of international data scientists to study this disease. Data from the comparator arms of four phase 3 clinical trials in first-line metastatic castration-resistant prostate cancer were obtained from Project Data Sphere, comprising 476 patients treated with docetaxel and prednisone from the ASCENT2 trial, 526 patients treated with docetaxel, prednisone, and placebo in the MAINSAIL trial, 598 patients treated with docetaxel, prednisone or prednisolone, and placebo in the VENICE trial, and 470 patients treated with docetaxel and placebo in the ENTHUSE 33 trial. Datasets consisting of more than 150 clinical variables were curated centrally, including demographics, laboratory values, medical history, lesion sites, and previous treatments. Data from ASCENT2, MAINSAIL, and VENICE were released publicly to be used as training data to predict the outcome of interest-namely, overall survival. Clinical data were also released for ENTHUSE 33, but data for outcome variables (overall survival and event status) were hidden from the challenge participants so that ENTHUSE 33 could be used for independent validation. Methods were evaluated using the integrated time-dependent area under the curve (iAUC). The reference model, based on eight clinical variables and a penalised Cox proportional-hazards model, was used to compare method performance. Further validation was done using data from a

  20. Acoustic Telemetry Evaluation of Juvenile Salmonid Passage and Survival at John Day Dam with Emphasis on the Prototype Surface Flow Outlet, 2008

    Energy Technology Data Exchange (ETDEWEB)

    Weiland, Mark A.; Ploskey, Gene R.; Hughes, James S.; Deng, Zhiqun; Fu, Tao; Monter, Tyrell J.; Johnson, Gary E.; Khan, Fenton; Wilberding, Matthew C.; Cushing, Aaron W.; Zimmerman, Shon A.; Faber, Derrek M.; Durham, Robin E.; Townsend, Richard L.; Skalski, John R.; Kim, Jina; Fischer, Eric S.; Meyer, Matthew M.

    2009-12-01

    The main purpose of the study was to evaluate the performance of Top Spill Weirs installed at two spillbays at John Day Dam and evaluate the effectiveness of these surface flow outlets at attracting juvenile salmon away from the powerhouse and reducing turbine passage. The Juvenile Salmonid Acoustic Telemetry System (JSATS) was used to estimate survival of juvenile salmonids passing the dam and also for calculating performance metrics used to evaluate the efficiency and effectiveness of the dam at passing juvenile salmonids.

  1. Right Ventricular Ejection Fraction using ECG-Gated First Pass Cardioangiography

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Young Hee; Lee, Hae Giu; Lee, Sung Yong; Park, Suk Min; Chung, Soo Kyo; Yim, Jeong Ik; Bahk, Yong Whee; Shinn, Kyung Sub; Kim, Young Gyun; Kwon, Soon Seog [Catholic University College of Medicine, Seoul (Korea, Republic of)

    1993-03-15

    Radionuclide cardioangiography has been widely applied and has played major roles in moninvasive assessment of cardiac function. Three techniques, first-pass gated first and gated equilibrium methods have commonly been used to evaluate right ventricular ejection fraction which usually abnormal in the patients with cardiopulmonary disease. It has been known that the gated first pass method is most accurate method among the three techniques in assessment of fight ventricular ejection fraction. The radionuclide right ventricular ejection fraction values were determined in 13 normal subjects and in 15 patients with chronic obstructive pulmonary disease by the gated first pass method and compared with those of the first pass method because there has been no published data of fight ejection fraction by the gated first pass method were compared with the defects from the pulmonary function test performed in the patients with chronic obstructive pulmomary disease. The results were as follows; 1) The values of fight ventricular ejection fraction by the gated first pass method were 50.1 +- 6.1% in normal subjects and 38.5 +- 8.5 in the patients with chronic obstructive pulmonary disease. There was statistically significant difference between the right ventricular ejection fraction of each of the two groups (p<0.05) 2) The right ventricular ejection fraction by the gated first pass method was not linearly correlated ith FEV{sub 1}, VC. DLCO. and FVC as well as P{sub a}O2 and P{sub a}CO2 of the patients with chronic obstructive pulmonary disease. We concluded that right ventricular ejection fraction by the gated first pass method using radionuclide cardioangiography may be useful in clinical assessment of the right ventricular function.

  2. Blind sensor calibration using approximate message passing

    International Nuclear Information System (INIS)

    Schülke, Christophe; Caltagirone, Francesco; Zdeborová, Lenka

    2015-01-01

    The ubiquity of approximately sparse data has led a variety of communities to take great interest in compressed sensing algorithms. Although these are very successful and well understood for linear measurements with additive noise, applying them to real data can be problematic if imperfect sensing devices introduce deviations from this ideal signal acquisition process, caused by sensor decalibration or failure. We propose a message passing algorithm called calibration approximate message passing (Cal-AMP) that can treat a variety of such sensor-induced imperfections. In addition to deriving the general form of the algorithm, we numerically investigate two particular settings. In the first, a fraction of the sensors is faulty, giving readings unrelated to the signal. In the second, sensors are decalibrated and each one introduces a different multiplicative gain to the measurements. Cal-AMP shares the scalability of approximate message passing, allowing us to treat large sized instances of these problems, and experimentally exhibits a phase transition between domains of success and failure. (paper)

  3. Linear Fixed-Field Multi-Pass Arcs for Recirculating Linear Accelerators

    International Nuclear Information System (INIS)

    Morozov, V.S.; Bogacz, S.A.; Roblin, Y.R.; Beard, K.B.

    2012-01-01

    Recirculating Linear Accelerators (RLA's) provide a compact and efficient way of accelerating particle beams to medium and high energies by reusing the same linac for multiple passes. In the conventional scheme, after each pass, the different energy beams coming out of the linac are separated and directed into appropriate arcs for recirculation, with each pass requiring a separate fixed-energy arc. In this paper we present a concept of an RLA return arc based on linear combined-function magnets, in which two and potentially more consecutive passes with very different energies are transported through the same string of magnets. By adjusting the dipole and quadrupole components of the constituting linear combined-function magnets, the arc is designed to be achromatic and to have zero initial and final reference orbit offsets for all transported beam energies. We demonstrate the concept by developing a design for a droplet-shaped return arc for a dog-bone RLA capable of transporting two beam passes with momenta different by a factor of two. We present the results of tracking simulations of the two passes and lay out the path to end-to-end design and simulation of a complete dog-bone RLA.

  4. Saudi sands, SCUDS, and survival.

    Science.gov (United States)

    Glendon, M P

    1993-01-01

    SCUD attacks were one of many challenges this pediatric nurse practitioner (NP) and Air Force Reserve flight nurse faced daily during Desert Shield and Desert Storm. Providing nursing care to sick and injured patients on board a C141 transport plane en route from Saudi Arabia to Germany was her primary responsibility. Additionally, many hours were spent filling sandbags, attending in-service classes, and practicing putting on a gas mask and protective suit. Although the war has been over for almost 3 years, the effects are long lasting. The author was able to use her wartime experience positively to gain insight into survival in today's violent society. As violence increases, NPs must reshape their focus and educate their clients about survival.

  5. A Population Study of Golden Eagles in the Altamont Pass Wind Resource Area: Population Trend Analysis, 1994-1997

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, W. G.; Jackman, R. E.; Hunt, T. L.; Driscoll, D. E.; Culp, L.

    1999-07-20

    The wind industry has annually reported 28-43 turbine blade strike casualties of golden eagles in the Altamont Pass Wind Resource Area, and many more carcasses have doubtless gone unnoticed. Because this species is especially sensitive to adult survival rate changes, we focused upon estimating the demographic trend of the population. In aerial surveys, we monitored survival within a sample of 179 radio-tagged eagles over a four-year period. We also obtained data on territory occupancy and reproduction of about 65 eagle pairs residing in the area. Of 61 recorded deaths of radio-tagged eagles during the four-year investigation, 23 (38%) were caused by wind turbine blade strikes. Additional fatalities were unrecorded because blade strikes sometimes destroy radio transmitters. Annual survival was estimated at 0.7867 (SE=0.0263) for non-territorial eagles and 0.8964 (SE=0.0371) for territorial ones. Annual reproduction was 0.64 (SE=0.08) young per territorial pair (0.25 per female). These parameters were used to estimate population growth rates under different modeling frameworks. At present, there are indications that a reserve of non-breeding adults still exists, i.e., there is an annual territorial reoccupancy rate of 100% and a low incidence (3%) of subadults as members of breeding pairs.

  6. A Population Study of Golden Eagles in the Altamont Pass Wind Resource Area: Population Trend Analysis, 1994-1997

    International Nuclear Information System (INIS)

    Predatory Bird Research Group Long Marine Laboratory

    1999-01-01

    The wind industry has annually reported 28-43 turbine blade strike casualties of golden eagles in the Altamont Pass Wind Resource Area, and many more carcasses have doubtless gone unnoticed. Because this species is especially sensitive to adult survival rate changes, we focused upon estimating the demographic trend of the population. In aerial surveys, we monitored survival within a sample of 179 radio-tagged eagles over a four-year period. We also obtained data on territory occupancy and reproduction of about 65 eagle pairs residing in the area. Of 61 recorded deaths of radio-tagged eagles during the four-year investigation, 23 (38%) were caused by wind turbine blade strikes. Additional fatalities were unrecorded because blade strikes sometimes destroy radio transmitters. Annual survival was estimated at 0.7867 (SE=0.0263) for non-territorial eagles and 0.8964 (SE=0.0371) for territorial ones. Annual reproduction was 0.64 (SE=0.08) young per territorial pair (0.25 per female). These parameters were used to estimate population growth rates under different modeling frameworks. At present, there are indications that a reserve of non-breeding adults still exists, i.e., there is an annual territorial re-occupancy rate of 100% and a low incidence (3%) of sub-adults as members of breeding pairs

  7. Setting pass scores for clinical skills assessment.

    Science.gov (United States)

    Liu, Min; Liu, Keh-Min

    2008-12-01

    In a clinical skills assessment, the decision to pass or fail an examinee should be based on the test content or on the examinees' performance. The process of deciding a pass score is known as setting a standard of the examination. This requires a properly selected panel of expert judges and a suitable standard setting method, which best fits the purpose of the examination. Six standard setting methods that are often used in clinical skills assessment are described to provide an overview of the standard setting process.

  8. Pass-fail grading: laying the foundation for self-regulated learning.

    Science.gov (United States)

    White, Casey B; Fantone, Joseph C

    2010-10-01

    Traditionally, medical schools have tended to make assumptions that students will "automatically" engage in self-education effectively after graduation and subsequent training in residency and fellowships. In reality, the majority of medical graduates out in practice feel unprepared for learning on their own. Many medical schools are now adopting strategies and pedagogies to help students become self-regulating learners. Along with these changes in practices and pedagogy, many schools are eliminating a cornerstone of extrinsic motivation: discriminating grades. To study the effects of the switch from discriminating to pass-fail grading in the second year of medical school, we compared internal and external assessments and evaluations for a second-year class with a discriminating grading scale (Honors, High Pass, Pass, Fail) and for a second-year class with a pass-fail grading scale. Of the measures we compared (MCATs, GPAs, means on second-year examinations, USMLE Step 1 scores, residency placement, in which there were no statistically significant changes), the only statistically significant decreases (lower performance with pass fail) were found in two of the second-year courses. Performance in one other course also improved significantly. Pass-fail grading can meet several important intended outcomes, including "leveling the playing field" for incoming students with different academic backgrounds, reducing competition and fostering collaboration among members of a class, more time for extracurricular interests and personal activities. Pass-fail grading also reduces competition and supports collaboration, and fosters intrinsic motivation, which is key to self-regulated, lifelong learning.

  9. Introduction to SURPH.1 analysis of release-recapture data for survival studies

    International Nuclear Information System (INIS)

    Smith, S.G.; Skalski, J.R.; Schlechte, J.W.; Hoffmann, A.; Cassen, V.

    1994-12-01

    Program SURPH is the culmination of several years of research to develop a comprehensive computer program to analyze survival studies of fish and wildlife populations. Development of this software was motivated by the advent of the PIT-tag (Passive Integrated Transponder) technology that permits the detection of salmonid smolt as they pass through hydroelectric facilities on the Snake and Columbia Rivers in the Pacific Northwest. Repeated detections of individually tagged smolt and analysis of their capture-histories permits estimates of downriver survival probabilities. Eventual installation of detection facilities at adult fish ladders will also permit estimation of ocean survival and upstream survival of returning salmon using the statistical methods incorporated in SURPH.1. However, the utility of SURPH.1 far exceeds solely the analysis of salmonid tagging studies. Release-recapture and radiotelemetry studies from a wide range of terrestrial and aquatic species have been analyzed using SURPH.1 to estimate discrete time survival probabilities and investigate survival relationships. The interactive computing environment of SURPH.1 was specifically developed to allow researchers to investigate the relationship between survival and capture processes and environmental, experimental and individual-based covariates. Program SURPH.1 represents a significant advancement in the ability of ecologists to investigate the interplay between morphologic, genetic, environmental and anthropogenic factors on the survival of wild species. It is hoped that this better understanding of risk factors affecting survival will lead to greater appreciation of the intricacies of nature and to improvements in the management of wild resources. This technical report is an introduction to SURPH.1 and provides a user guide for both the UNIX and MS-Windows reg-sign applications of the SURPH software

  10. Pass-through of exchange rates and tariffs in Greek-US tobacco trade

    OpenAIRE

    Rezitis, Anthony N.; Brown, A. Blake

    1999-01-01

    The paper examines the extent to which exchange rate and unit tariff changes are passed-through in US import prices of unmanufactured Greek oriental tobacco. The results indicate partial pass-through of exchange rates and tariffs. Exchange rate pass-through is about 0.272 and tariff pass-through about 0.185. One possible reason for the partial pass-through is oligopoly in tobacco exporting. Oligopoly would imply that depreciation of the drachma relative to the US dollar benefits tobacco expor...

  11. Realisation of low-voltage square-root-domain all-pass filters

    Directory of Open Access Journals (Sweden)

    Farooq A. Khanday

    2013-10-01

    Full Text Available Novel l ow-voltage first-order and second-order square-root-domain all-pass filters derived systematically by means of transfer function decomposition and state -space synthesis techniques are proposed. The employment of only a few geometric-mean cells and grounded capacitors permits the circuits to absorb shunt parasitic capacitances, which is desirable for production in monolithic form . The circuits enjoy the features of electronic adjustment of frequency characteristics, wider dynamic range and low-voltage environment operation. The filters are employed to design high-order all-pass filters using cascade approach. First-order low-pass and second-order band-pass filters, being the inherited building blocks of the proposed low-order all-pass filters are also discussed. The behaviour of the filters is evaluated through simulations using Taiwan semiconductor manufacturing company 0.25 μm level-3 complementary metal oxide semiconductor process parameters, where the most important performance factors are considered.

  12. Le survivant sans le syndrome Schreber

    Directory of Open Access Journals (Sweden)

    Richard Figuier

    2006-09-01

    Full Text Available On a pensé la catastrophe, mais a-t-on suffisamment pensé la survivance et la figure du survivant ? Ce n'est pas un hasard si celle-ci est au centre de Masse et puissance, oeuvre dans laquelle Canetti interroge la « mauvaise » survivance responsable de la poursuite de la logique de guerre. Mais où trouver la « bonne » ? Revenir de la catastrophe ne suffit pas pour être un « survivant authentique », selon l'expression de Kafka. Il faut avoir dépassé, avec Primo Levi et Robert Antelme, l'opposition de la vie comme croissance continue et de la mort comme son horrible contraire, par le don, dans la pauvreté solidaire, de cette vie retrouvée.Hemos reflexionado acerca de la catástrofe, pero ¿hemos meditado lo suficiente sobre la supervivencia y el superviviente? No es una coincidencia si el superviviente es el tema principal de Masse et puissance, obra en la cual Canetti analiza la «mala» supervivencia responsable de la persistencia de la lógica de guerra ¿Dónde sin embargo podemos encontrar la «buena» supervivencia? Superar la catástrofe no es suficiente para ser un «auténtico superviviente», según Kafka. Es fundamental ir más allá, con Primo Levi y Robert Antelme, de la oposición entre la vida, como crecimiento continuo, y la muerte, como su espantoso contrario, mediante la donación de forma solidaria de esta vida reencontrada.Disaster is the theme of many studies, but what about survival and of the figure of the survivor? This issue is central in Mass and power, work in which Canetti questions the “bad” survival, responsible for the continuation of the logic of war. But is there any “good” survival? Coming back from the catastrophe is not enough to be an “authentic survivor”, according to Kafka’s expression. To achieve this, it is necessary to have exceeded, with PrimoLevi and Robert Antelme, the opposition of life as a continuous growth and of death as its horrible opposite, by the gift, in a

  13. Exchange rate pass-through in Switzerland: Evidence from vector autoregressions

    OpenAIRE

    Jonas Stulz

    2007-01-01

    This study investigates the pass-through of exchange rate and import price shocks to different aggregated prices in Switzerland. The baseline analysis is carried out with recursively identified vector autoregressive (VAR) models. The data set comprises monthly observations, and pass-through effects are quantified by means of impulse response functions. Evidence shows that the exchange rate pass-through to import prices is substantial (although incomplete), but only moderate to total consumer ...

  14. Exchange rate pass-through and the role of international distribution channels

    OpenAIRE

    Desiraju, Ramarao; Shrikhande, Milind

    1996-01-01

    Manufacturers selling in foreign markets often do not completely pass on the effects of fluctuations in exchange rates to the prices of their products. Our paper addresses this puzzle and studies the effects of the international distribution channel on exchange rate pass-through. We develop an exchange rate pass-through model that takes into account the role of an intermediary between a domestic manufacturer and its consumers in a foreign market. We find that the magnitude of the pass-through...

  15. Setting Pass Scores for Clinical Skills Assessment

    Directory of Open Access Journals (Sweden)

    Min Liu

    2008-12-01

    Full Text Available In a clinical skills assessment, the decision to pass or fail an examinee should be based on the test content or on the examinees' performance. The process of deciding a pass score is known as setting a standard of the examination. This requires a properly selected panel of expert judges and a suitable standard setting method, which best fits the purpose of the examination. Six standard setting methods that are often used in clinical skills assessment are described to provide an overview of the standard setting process.

  16. Single beam pass migmacell method and apparatus

    International Nuclear Information System (INIS)

    Maglich, B.C.; Nering, J.E.; Mazarakis, M.G.; Miller, R.A.

    1976-01-01

    The invention provides improvements in migmacell apparatus and method by dispensing with the need for metastable confinement of injected molecular ions for multiple precession periods. Injected molecular ions undergo a 'single pass' through the reaction volume. By preconditioning the injected beam such that it contains a population distribution of molecules in higher vibrational states than in the case of a normal distribution, injected molecules in the single pass exper-ience collisionless dissociation in the migmacell under magnetic influence, i.e., so-called Lorentz dissociation. Dissociationions then form atomic migma

  17. Security analysis and improvements to the PsychoPass method.

    Science.gov (United States)

    Brumen, Bostjan; Heričko, Marjan; Rozman, Ivan; Hölbl, Marko

    2013-08-13

    In a recent paper, Pietro Cipresso et al proposed the PsychoPass method, a simple way to create strong passwords that are easy to remember. However, the method has some security issues that need to be addressed. To perform a security analysis on the PsychoPass method and outline the limitations of and possible improvements to the method. We used the brute force analysis and dictionary attack analysis of the PsychoPass method to outline its weaknesses. The first issue with the Psychopass method is that it requires the password reproduction on the same keyboard layout as was used to generate the password. The second issue is a security weakness: although the produced password is 24 characters long, the password is still weak. We elaborate on the weakness and propose a solution that produces strong passwords. The proposed version first requires the use of the SHIFT and ALT-GR keys in combination with other keys, and second, the keys need to be 1-2 distances apart. The proposed improved PsychoPass method yields passwords that can be broken only in hundreds of years based on current computing powers. The proposed PsychoPass method requires 10 keys, as opposed to 20 keys in the original method, for comparable password strength.

  18. Validation of the one pass measure for motivational interviewing competence.

    Science.gov (United States)

    McMaster, Fiona; Resnicow, Ken

    2015-04-01

    This paper examines the psychometric properties of the OnePass coding system: a new, user-friendly tool for evaluating practitioner competence in motivational interviewing (MI). We provide data on reliability and validity with the current gold-standard: Motivational Interviewing Treatment Integrity tool (MITI). We compared scores from 27 videotaped MI sessions performed by student counselors trained in MI and simulated patients using both OnePass and MITI, with three different raters for each tool. Reliability was estimated using intra-class coefficients (ICCs), and validity was assessed using Pearson's r. OnePass had high levels of inter-rater reliability with 19/23 items found from substantial to almost perfect agreement. Taking the pair of scores with the highest inter-rater reliability on the MITI, the concurrent validity between the two measures ranged from moderate to high. Validity was highest for evocation, autonomy, direction and empathy. OnePass appears to have good inter-rater reliability while capturing similar dimensions of MI as the MITI. Despite the moderate concurrent validity with the MITI, the OnePass shows promise in evaluating both traditional and novel interpretations of MI. OnePass may be a useful tool for developing and improving practitioner competence in MI where access to MITI coders is limited. Copyright © 2015. Published by Elsevier Ireland Ltd.

  19. Adaptation, growth and survival of tilapia (Oreochromis niloticus) in Bafgh brackish water

    OpenAIRE

    Sarsangi, A.H.; Mohammadi, M.; Mashaii, N.; Rajabipou, F.; Bitaraf, A.; Askari, H.M.; Moazedi, J.; Nezamabadi, H.; Hosseinzadeh Sahafi, H.

    2012-01-01

    An experiment was conducted to evaluate the possibility of adaptation, growth and survival of Nile tilapia (Oreochromis niloticus) with 0.3g initial weight and red tilapia (Oreochromis sp.) with 0.7g initial weight in underground brackish water. Fry of Nile tilapia and red tilapia imported from Indonesia and after passing larviculture (25g) were examined separately in fiber glass tank by two replicate. Fish were fed at a restricted feeding program according to standard table during the light ...

  20. The Challenges Facing Accounting Education: The Nigerian ...

    African Journals Online (AJOL)

    The need of the accounting profession to effectively and continuously meet new challenges confronting it and adapt its services to changing conditions and circumstances has become a necessity to the survival of the profession and the society. The challenges confronting the accountant on his role to the society at large in a ...

  1. Time variation in European carbon pass-through rates in electricity futures prices

    International Nuclear Information System (INIS)

    Huisman, Ronald; Kiliç, Mehtap

    2015-01-01

    The European Union Emissions Trading Scheme is a means to price emission allowances. Electricity market prices should reflect these market prices of emission allowances as they are a cost factor for power producers. The pass-through rate is the fraction of the emission allowance price that is passed through to electricity market prices. It is often measured and presented as an average or a fixed estimate over some time period. However, we expect that the pass-through rates should actually vary over time as electricity supply curves reflect the marginal costs of different producers that differ in emission intensity. We apply a Kalman Filter approach to observe pass-through rates in Germany and U.K. and find strong support for time varying instead of fixed pass-through rates. Although policy makers are interested in the impact of a policy on average, our results indicate that one needs to be careful with the time-frame over which pass-through rates are measured for policy evaluation, as an incorrect chosen evaluation period could cause an under- or overestimation of the pass-through rate. In addition, our model helps to provide policy makers with insight in the development of pass-through rates when market circumstances change with respect to power production. - Highlights: • We analyse the time-variation of the emission pass-through rate in power prices. • We examine historical futures prices for Germany and the U.K. • We test the hypothesis by using the Kalman Filter methodology. • Strong support is found that pass-through rates vary over time. • The chosen time-frame for pass-through rates is important for policy evaluation.

  2. Contact conditions in skin-pass rolling

    DEFF Research Database (Denmark)

    Kijima, Hideo; Bay, Niels

    2007-01-01

    The special contact conditions in skin-pass rolling of steel strip is analysed by studying plane strain upsetting of thin sheet with low reduction applying long narrow tools and dry friction conditions. An extended sticking region is estimated by an elasto-plastic FEM analysis of the plane strain...... upsetting. This sticking region causes a highly inhomogeneous elasto-plastic deformation with large influence of work-hardening and friction. A numerical analysis of skin-pass rolling shows the same contact conditions, i.e. an extended sticking region around the center of the contact zone. The calculated...... size of the sticking region with varying contact length and pressure/reduction is experimentally verified by plane strain upsetting tests measuring the local surface deformation of the work pieces after unloading....

  3. Upaya Meningkatkan Kemampuan Passing Bawah Bola Voli Pada

    OpenAIRE

    Irawan, Dedi

    2017-01-01

    This research uses research "Classroom Action Research" (Classroom Action Research) with variables: Improved Passing Down volleyball through media modified rubber ball. Subjects in this study were fifth grade students of State Elementary School 23 Palus Hulu subdistrict Belimbing Melawi totaling 28 students. This research technique using test and measurement, a test with a grating instrument measuring learning outcomes passing down the volleyball game. Analysis of data using percentages. Thes...

  4. A COMPARATIVE STUDY RELATING PASS BETWEEN MALE AND FEMALE BASKETBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Antonios THEOHAROPOULOS

    2010-04-01

    Full Text Available The main goal of this research is to examine the importance of different kind of passes through their frequency of appearance and success that male and female basketball players execute in Greek championships.The sample consisted of male and female teams of Thessaloniki - Greece. The 1st group consisted of male teams (18 from different divisions while the 2nd group consisted of female teams (10. Data collection was based on personal observation by a research team, who registries the kind of passes that took place either from the sampleteam or the opposite teams. The passes that were registered are: behind the back, chest, overhead, push, hand with hand, bounce and baseball pass. The analysis of variance (Anova in types of passes was formed, based on the factor “sex” (male-female. Specifically the comparisons were made between: a the total number of eachpass b their successful number c their frequency of appearance d and their total successful percentage. The results indicate that statistically significant differences exist between the two sexes, concerning the total number, the successful number and the percentages of success for the most used passes in Greek basketball. The analysis indicates that male and female basketball players tend to use different kind of passes during activity.

  5. 9 CFR 310.6 - Carcasses and parts passed for cooking; marking.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses and parts passed for cooking... INSPECTION AND CERTIFICATION POST-MORTEM INSPECTION § 310.6 Carcasses and parts passed for cooking; marking. Carcasses and parts passed for cooking shall be marked conspicuously on the surface tissues thereof by a...

  6. The Double Burden of Malnutrition in Countries Passing through the Economic Transition.

    Science.gov (United States)

    Prentice, Andrew M

    2018-01-01

    Undernutrition in both its acute and chronic forms (wasting and stunting) is strongly inversely correlated with the wealth of nations. Consequently, as many low- and middle-income countries (LMICs) achieve economic advancement and pass through the so-called "nutrition transition," their rates of undernutrition decline. Many countries successfully achieved the Millennium Development Goal of halving undernutrition and whole continents have been transformed in recent decades. The exception is Africa where the slower rates of decline in the prevalence of undernutrition has been overtaken by population growth so that the absolute number of stunted children is rising. In many regions, economic transition is causing a rapid increase in the number of overweight and obese people. The rapidity of this rise is such that many nations bear the simultaneous burdens of under- and overnutrition; termed the "double burden" of malnutrition. This double burden, accompanied as it is by the unfinished agenda of high levels of infectious diseases, is crippling the health systems of many LMICs and thus requires urgent attention. Although the prognosis looks threatening for many poor countries, they have the advantage of being able to learn from the mistakes made by other nations that have passed through the transition before them. Concerted action across many arms of government would achieve huge future dividends in health and wealth for any nations that can grasp the challenge. © 2018 S. Karger AG, Basel.

  7. Statistical variability and confidence intervals for planar dose QA pass rates

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, Daniel W.; Nelms, Benjamin E.; Attwood, Kristopher; Kumaraswamy, Lalith; Podgorsak, Matthew B. [Department of Physics, State University of New York at Buffalo, Buffalo, New York 14260 (United States) and Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263 (United States); Canis Lupus LLC, Merrimac, Wisconsin 53561 (United States); Department of Biostatistics, Roswell Park Cancer Institute, Buffalo, New York 14263 (United States); Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263 (United States); Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263 (United States); Department of Molecular and Cellular Biophysics and Biochemistry, Roswell Park Cancer Institute, Buffalo, New York 14263 (United States) and Department of Physiology and Biophysics, State University of New York at Buffalo, Buffalo, New York 14214 (United States)

    2011-11-15

    Purpose: The most common metric for comparing measured to calculated dose, such as for pretreatment quality assurance of intensity-modulated photon fields, is a pass rate (%) generated using percent difference (%Diff), distance-to-agreement (DTA), or some combination of the two (e.g., gamma evaluation). For many dosimeters, the grid of analyzed points corresponds to an array with a low areal density of point detectors. In these cases, the pass rates for any given comparison criteria are not absolute but exhibit statistical variability that is a function, in part, on the detector sampling geometry. In this work, the authors analyze the statistics of various methods commonly used to calculate pass rates and propose methods for establishing confidence intervals for pass rates obtained with low-density arrays. Methods: Dose planes were acquired for 25 prostate and 79 head and neck intensity-modulated fields via diode array and electronic portal imaging device (EPID), and matching calculated dose planes were created via a commercial treatment planning system. Pass rates for each dose plane pair (both centered to the beam central axis) were calculated with several common comparison methods: %Diff/DTA composite analysis and gamma evaluation, using absolute dose comparison with both local and global normalization. Specialized software was designed to selectively sample the measured EPID response (very high data density) down to discrete points to simulate low-density measurements. The software was used to realign the simulated detector grid at many simulated positions with respect to the beam central axis, thereby altering the low-density sampled grid. Simulations were repeated with 100 positional iterations using a 1 detector/cm{sup 2} uniform grid, a 2 detector/cm{sup 2} uniform grid, and similar random detector grids. For each simulation, %/DTA composite pass rates were calculated with various %Diff/DTA criteria and for both local and global %Diff normalization

  8. Survivable pulse power space radiator

    Science.gov (United States)

    Mims, James; Buden, David; Williams, Kenneth

    1989-01-01

    A thermal radiator system is described for use on an outer space vehicle, which must survive a long period of nonuse and then radiate large amounts of heat for a limited period of time. The radiator includes groups of radiator panels that are pivotally connected in tandem, so that they can be moved to deployed configuration wherein the panels lie largely coplanar, and to a stowed configuration wherein the panels lie in a stack to resist micrometeorite damage. The panels are mounted on a boom which separates a hot power source from a payload. While the panels are stowed, warm fluid passes through their arteries to keep them warm enough to maintain the coolant in a liquid state and avoid embrittlement of material. The panels can be stored in a largely cylindrical shell, with panels progressively further from the boom being of progressively shorter length.

  9. Approach, passage, and survival of juvenile salmonids at Little Goose Dam, Washington: Post-construction evaluation of a temporary spillway weir, 2009

    Science.gov (United States)

    Beeman, J.W.; Braatz, A.C.; Hansel, H.C.; Fielding, S.D.; Haner, P.V.; Hansen, G.S.; Shurtleff, D.J.; Sprando, J.M.; Rondorf, D.W.

    2010-01-01

    This report describes a study of dam passage and survival of radio-tagged juvenile salmonids after installation of a temporary spillway weir (TSW) at Little Goose Dam, Washington, in 2009. The purpose of the study was to document fish passage and survival when the dam was operated with the TSW in place. Spillway weirs are one of several methods used to improve downstream passage of juvenile salmonids. Each spillway weir design is based on the concept of providing an overflow weir with a depth more similar to the natural migration depth of juvenile salmonids than conventional spill bays. Little Goose Dam was the last of the four lower Snake River dams to have a spillway weir installed. This was the first year that some form of surface passage device was operating at all Snake River and Columbia River dams between Lewiston, Idaho, and the Columbia River estuary. The study design stipulated that a total of 30 percent of the river discharge would continuously be passed over the TSW and the conventional spill bays, and this percentage was achieved. The TSW also was to be operated at the 'low crest' elevation during the spring and the 'high crest' elevation during the summer, but the TSW was only operated at the low crest elevation during this study. Behavior, passage, and survival of spring and summer juvenile salmonid migrants passing through Little Goose Dam were examined using radio telemetry. Survival was estimated using the Route Specific Survival Model (RSSM) by releasing tagged fish near Central Ferry State Park 21 kilometers upstream of the dam and in the tailrace approximately 0.5 kilometer downstream of the dam. From April 18 to May 21, 2009, 1,520 yearling Chinook salmon (Oncorhynchus tshawytscha) and 1,517 juvenile steelhead (O. mykiss) were radio tagged and released. From June 6 to July 5, 2009, 4,251 subyearling Chinook salmon (O. tshawytscha) were radio tagged and released. Release dates of subyearling Chinook salmon were selected to avoid 'reservoir

  10. A prototype for the PASS Permanent All Sky Survey

    Science.gov (United States)

    Deeg, H. J.; Alonso, R.; Belmonte, J. A.; Horne, K.; Alsubai, K.; Collier Cameron, A.; Doyle, L. R.

    2004-10-01

    A prototype system for the Permanent All Sky Survey (PASS) project is presented. PASS is a continuous photometric survey of the entire celestial sphere with a high temporal resolution. Its major objectives are the detection of all giant-planet transits (with periods up to some weeks) across stars up to mag 10.5, and to deliver continuously photometry that is useful for the study of any variable stars. The prototype is based on CCD cameras with short focal length optics on a fixed mount. A small dome to house it at Teide Observatory, Tenerife, is currently being constructed. A placement at the antarctic Dome C is also being considered. The prototype will be used for a feasibility study of PASS, to define the best observing strategies, and to perform a detailed characterization of the capabilities and scope of the survey. Afterwards, a first partial sky surveying will be started with it. That first survey may be able to detect transiting planets during its first few hundred hours of operation. It will also deliver a data set around which software modules dealing with the various scientific objectives of PASS will be developed. The PASS project is still in its early phase and teams interested in specific scientific objectives, in providing technical expertise, or in participating with own observations are invited to collaborate.

  11. A survival programme

    International Nuclear Information System (INIS)

    Vester, F.

    1978-01-01

    The book is a non-speculative information source on ecological problems and their possible solutions. It is a 'programme' from a twofold point of view: it determines political and scientific-technological objectives and it transfers knowledge by mental steps with techniques of programmed instruction. Thus emphasis is laid on detailed problems, especially by conscionsly challenged redundancies, and, on the other hand, a greater context is presented. Selected facts are examined under their different aspects, interactions and control circuits are described. Each chapter will speak for itself after the introduction has been read but is related to other chapters by cross references, illustrative material, a glossary and a comprehensive list of references. The 'Survival Programme' is a realistic and challenging discussion with the problem of 'Ecology in the Industrial Age'. It adresses scientists from various disciplines but also offers itself as a compendium to laymen in search of information, members of citizens initiatives and responsible representants of the political and industrial world. (orig./HP) [de

  12. Terrorismihirm sunnib muretsema kalleid mikrokiibiga passe / Andrus Karnau

    Index Scriptorium Estoniae

    Karnau, Andrus

    2005-01-01

    Alates 1. septembrist 2006 peavad kõik EL-i liikmesriigid hakkama väljastama mikrokiibiga varustatud passe, mille hinnaks võib kujuneda kuni 1000 krooni ja kehtivus lüheneb viiele aastale. Mikrokiip sisaldab inimese biomeetrilisi andmeid - esialgu vaid näokujutist, alates 2008. aastast näpujälgi ning hiljem ka andmeid silmaiirise ja juuksevärvi kohta. Lisa: Biomeetriline pass peidab intiimseid isikuandmeid. Kommenteerib Kohtuekspertiisi ja Kriminalistika Keskuse infojuht Aivar Pau

  13. Survival and prognostic factors at time of diagnosis in high-grade appendicular osteosarcoma

    DEFF Research Database (Denmark)

    Colding-Rasmussen, Thomas; Thorn, Andrea Pohly; Horstmann, Peter

    2018-01-01

    BACKGROUND: Survival of patients with high-grade osteosarcoma (HOS), the most common primary bone cancer, has not improved significantly the last 30 years and the disease remains a major challenge. The purpose of this study is to evaluate survival in relation to prognostic factors at time of diag...

  14. Monitoring of Juvenile Subyearling Chinook Salmon Survival and Passage at John Day Dam, Summer 2010

    Energy Technology Data Exchange (ETDEWEB)

    Weiland, Mark A.; Ploskey, Gene R.; Hughes, James S.; Woodley, Christa M.; Deng, Zhiqun; Carlson, Thomas J.; Skalski, J. R.; Townsend, Richard L.

    2012-11-15

    The purpose of this study was to evaluate dam passage survival of subyearling Chinook salmon (Oncorhynchus tshawytscha; CH0) at John Day Dam (JDA) during summer 2010. This study was conducted by researchers from the Pacific Northwest National Laboratory (PNNL) in collaboration with the Pacific States Marine Fisheries Commission (PSMFC) and the University of Washington (UW). The study was designed to estimate the effects of 30% and 40% spill treatment levels on single release survival rates of CH0 passing through two reaches: (1) the dam, and 40 km of tailwater, (2) the forebay, dam, and 40 km of tailwater. The study also estimated additional passage performance measures which are stipulated in the Columbia Basin Fish Accords.

  15. A field evaluation of an external and neutrally buoyant acoustic transmitter for juvenile salmon: implications for estimating hydroturbine passage survival.

    Directory of Open Access Journals (Sweden)

    Richard S Brown

    Full Text Available Turbine-passed fish are exposed to rapid decreases in pressure which can cause barotrauma. The presence of an implanted telemetry tag increases the likelihood of injury or death from exposure to pressure changes, thus potentially biasing studies evaluating survival of turbine-passed fish. Therefore, a neutrally buoyant externally attached tag was developed to eliminate this bias in turbine passage studies. This new tag was designed not to add excess mass in water or take up space in the coelom, having an effective tag burden of zero with the goal of reducing pressure related biases to turbine survival studies. To determine if this new tag affects fish performance or susceptibility to predation, it was evaluated in the field relative to internally implanted acoustic transmitters (JSATS; Juvenile Salmon Acoustic Telemetry System used widely for survival studies of juvenile salmonids. Survival and travel time through the study reach was compared between fish with either tag type in an area of high predation in the Snake and Columbia rivers, Washington. An additional group of fish affixed with neutrally-buoyant dummy external tags were implanted with passive integrated transponder (PIT tags and recovered further downstream to assess external tag retention and injury. There were no significant differences in survival to the first detection site, 12 river kilometers (rkm downstream of release. Travel times were also similar between groups. Conversely, externally-tagged fish had reduced survival (or elevated tag loss to the second detection site, 65 rkm downstream. In addition, the retention study revealed that tag loss was first observed in fish recaptured approximately 9 days after release. Results suggest that this new tag may be viable for short term (<8 days single-dam turbine-passage studies and under these situations, may alleviate the turbine passage-related bias encountered when using internal tags, however further research is needed to

  16. A field evaluation of an external and neutrally buoyant acoustic transmitter for juvenile salmon: implications for estimating hydroturbine passage survival.

    Science.gov (United States)

    Brown, Richard S; Deng, Z Daniel; Cook, Katrina V; Pflugrath, Brett D; Li, Xinya; Fu, Tao; Martinez, Jayson J; Li, Huidong; Trumbo, Bradly A; Ahmann, Martin L; Seaburg, Adam G

    2013-01-01

    Turbine-passed fish are exposed to rapid decreases in pressure which can cause barotrauma. The presence of an implanted telemetry tag increases the likelihood of injury or death from exposure to pressure changes, thus potentially biasing studies evaluating survival of turbine-passed fish. Therefore, a neutrally buoyant externally attached tag was developed to eliminate this bias in turbine passage studies. This new tag was designed not to add excess mass in water or take up space in the coelom, having an effective tag burden of zero with the goal of reducing pressure related biases to turbine survival studies. To determine if this new tag affects fish performance or susceptibility to predation, it was evaluated in the field relative to internally implanted acoustic transmitters (JSATS; Juvenile Salmon Acoustic Telemetry System) used widely for survival studies of juvenile salmonids. Survival and travel time through the study reach was compared between fish with either tag type in an area of high predation in the Snake and Columbia rivers, Washington. An additional group of fish affixed with neutrally-buoyant dummy external tags were implanted with passive integrated transponder (PIT) tags and recovered further downstream to assess external tag retention and injury. There were no significant differences in survival to the first detection site, 12 river kilometers (rkm) downstream of release. Travel times were also similar between groups. Conversely, externally-tagged fish had reduced survival (or elevated tag loss) to the second detection site, 65 rkm downstream. In addition, the retention study revealed that tag loss was first observed in fish recaptured approximately 9 days after release. Results suggest that this new tag may be viable for short term (<8 days) single-dam turbine-passage studies and under these situations, may alleviate the turbine passage-related bias encountered when using internal tags, however further research is needed to confirm this.

  17. Linking behavior, physiology, and survival of Atlantic Salmon smolts during estuary migration

    Science.gov (United States)

    Stich, Daniel S.; Zydlewski, Gayle B.; Kocik, John F.; Zydlewski, Joseph D.

    2015-01-01

    Decreased marine survival is identified as a component driver of continued declines of Atlantic Salmon Salmo salar. However, estimates of marine mortality often incorporate loss incurred during estuary migration that may be mechanistically distinct from factors affecting marine mortality. We examined movements and survival of 941 smolts (141 wild and 800 hatchery-reared fish) released in freshwater during passage through the Penobscot River estuary, Maine, from 2005 to 2013. We related trends in estuary arrival date, movement rate, and survival to fish characteristics, migratory history, and environmental conditions in the estuary. Fish that experienced the warmest thermal history arrived in the estuary 8 d earlier than those experiencing the coolest thermal history during development. Estuary arrival date was 10 d later for fish experiencing high flow than for fish experiencing low flow. Fish released furthest upstream arrived in the estuary 3 d later than those stocked further downstream but moved 0.5 km/h faster through the estuary. Temporally, movement rate and survival in the estuary both peaked in mid-May. Spatially, movement rate and survival both decreased from freshwater to the ocean. Wild smolts arrived in the estuary later than hatchery fish, but we observed no change in movement rate or survival attributable to rearing history. Fish with the highest gill Na+, K+-ATPase activity incurred 25% lower mortality through the estuary than fish with the lowest gill Na+, K+-ATPase activity. Smolt survival decreased (by up to 40%) with the increasing number of dams passed (ranging from two to nine) during freshwater migration. These results underscore the importance of physiological preparedness on performance and the delayed, indirect effects of dams on survival of Atlantic Salmon smolts during estuary migration, ultimately affecting marine survival estimates.

  18. [Is survival enough? Challenges of the integration of health and well-being in the third world].

    Science.gov (United States)

    Brachet-Márquez, V

    1992-01-01

    In this paper the paths taken by developing countries to improve the health and well-being of their populations in a context of diminishing resources is discussed. Emphasis is placed on Latin American countries and the objective is to clarify the changing nature of the relationship between health and social well-being in the 1970s and 1980s. In the second part of the paper three viable and different political scenarios to confront this problem are presented: 1) survival without well-being; 2) survival and eradication of extreme poverty, and 3) survival, eradication of extreme poverty, and selective reconversion of the poor.

  19. 9 CFR 381.79 - Passing of carcasses and parts.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Passing of carcasses and parts. 381.79 Section 381.79 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Carcasses and Parts § 381.79 Passing of carcasses and parts. Each carcass and all organs and other parts of...

  20. An Empirical Study of Exchange Rate Pass-Through in China

    OpenAIRE

    Xiaowen Jin

    2012-01-01

    This paper seeks to estimate exchange rate pass-through in China and investigate its relationship with monetary policy. Linear and VAR models are applied to analyze robustness. The linear model shows that, over the long run, a 1% appreciation of NEER causes a decline in the CPI inflation rate of 0.132% and PPI inflation rate of 0.495%. The VAR model supports the results of the linear model, suggesting a fairly low CPI pass-through and relatively higher PPI pass-through. Furthermore, thi...

  1. SURVIVAL ANALYSIS AND LENGTH-BIASED SAMPLING

    Directory of Open Access Journals (Sweden)

    Masoud Asgharian

    2010-12-01

    Full Text Available When survival data are colleted as part of a prevalent cohort study, the recruited cases have already experienced their initiating event. These prevalent cases are then followed for a fixed period of time at the end of which the subjects will either have failed or have been censored. When interests lies in estimating the survival distribution, from onset, of subjects with the disease, one must take into account that the survival times of the cases in a prevalent cohort study are left truncated. When it is possible to assume that there has not been any epidemic of the disease over the past period of time that covers the onset times of the subjects, one may assume that the underlying incidence process that generates the initiating event times is a stationary Poisson process. Under such assumption, the survival times of the recruited subjects are called “lengthbiased”. I discuss the challenges one is faced with in analyzing these type of data. To address the theoretical aspects of the work, I present asymptotic results for the NPMLE of the length-biased as well as the unbiased survival distribution. I also discuss estimating the unbiased survival function using only the follow-up time. This addresses the case that the onset times are either unknown or known with uncertainty. Some of our most recent work and open questions will be presented. These include some aspects of analysis of covariates, strong approximation, functional LIL and density estimation under length-biased sampling with right censoring. The results will be illustrated with survival data from patients with dementia, collected as part of the Canadian Study of Health and Aging (CSHA.

  2. The effect of adding fish oil to parenteral nutrition on hepatic mononuclear cell function and survival after intraportal bacterial challenge in mice.

    Science.gov (United States)

    Moriya, Tomoyuki; Fukatsu, Kazuhiko; Maeshima, Yoshinori; Ikezawa, Fumie; Hashiguchi, Yojiro; Saitoh, Daizoh; Miyazaki, Masaru; Hase, Kazuo; Yamamoto, Junji

    2012-05-01

    Parenteral nutrition (PN) is indispensable for meeting caloric and substrate needs of patients who cannot receive adequate amounts of enteral nutrition; however, PN impairs hepatic immunity. We examined the effects of ω-3 and -6 polyunsaturated fatty acids, added individually to fat-free PN, on hepatic immunity in a murine model. We focused on serum liver enzymes, cytokine production, histopathology, and the outcomes after intraportal bacterial challenge. Male Institute of Cancer Research mice were randomized into 4 groups; ad libitum chow (CHOW), fat-free PN (FF-PN), PN + fish oil (FO-PN), or PN + safflower oil (SO-PN). After the mice had been fed for 5 days, hepatic mononuclear cells (MNCs) were isolated. The number of MNCs was counted and cytokine production (tumor necrosis factor [TNF]-α and interleukin [IL]-10) by hepatic MNCs in response to lipopolysaccharide (LPS) was measured. Blood samples were analyzed for hepatobiliary biochemical parameters. Moreover, 1.0 × 10(7) pseudomonas aeruginosa were delivered by intraportal injection. Survival and histology were examined. Hepatic MNC numbers were significantly less in the FO-PN and FF-PN than in the CHOW group, whereas the SO-PN group showed moderate recovery of hepatic MNC numbers. The CHOW, FO-PN, and SO-PN groups showed LPS dose-dependent increases in TNF-α levels. These increases were blunted in the FF-PN group. IL-10 levels were increased LPS dose-dependently in the CHOW and FO-PN groups, but no marked changes were observed with LPS stimulation in the SO-PN and FF-PN groups. Plasma levels of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase were significantly greater in the FF-PN than in the FO- and SO-PN and CHOW groups. The FO-PN group showed significantly improved survival compared with the SO-PN and FF-PN groups, showing essentially no morphologic hepatic abnormalities. Addition of fish oil to PN was advantageous in terms of reversing PN-induced deterioration of hepatic

  3. Safety analysis of passing maneuvers using extreme value theory

    Directory of Open Access Journals (Sweden)

    Haneen Farah

    2017-04-01

    The results indicate that this is a promising approach for safety evaluation. On-going work of the authors will attempt to generalize this method to other safety measures related to passing maneuvers, test it for the detailed analysis of the effect of demographic factors on passing maneuvers' crash probability and for its usefulness in a traffic simulation environment.

  4. Low-sensitivity active filter realization using a complex all-pass filter

    Science.gov (United States)

    Regalia, Phillip A.; Mitra, Sanjit K.

    1987-04-01

    A wide class of continuous-time transfer functions may be implemented as the parallel combination of two all-pass filters, including Butterworth, Chebyshev, and elliptic low-pass approximations of odd order. Here, the realization of even-order low-pass classical approximations is considered, and it is shown that they may be decomposed in terms of complex all-pass functions. A systematic realization approach, based on scattering domain simulation (i.e., wave active filters), allows for a low-sensitivity active filter implementation. Further insight into the low-sensitivity property is gained by connecting the insertion loss of doubly terminated antimetric networks with the imaginary return loss of complex lossless networks.

  5. An estimation of the exchange rate pass-through to prices in Mexico

    OpenAIRE

    Josué Fernando Cortés Espada

    2013-01-01

    This paper estimates the magnitude of the exchange rate pass-through to consumer prices in Mexico. Moreover, it analyzes if the pass-through dynamics have changed in recent years. In particular, it uses a methodology that generates results consistent with the hierarchy implicit in the CPI. The results suggest that the exchange rate pass-through to the general price level is low and not statistically significant. However, the pass-through is positive and significant for goods prices. Furthermo...

  6. Genome-wide association study of prostate cancer-specific survival

    DEFF Research Database (Denmark)

    Szulkin, Robert; Karlsson, Robert; Whitington, Thomas

    2015-01-01

    BACKGROUND: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical. METHODS: We performed a genome-wide survival analysis of cause-specific death in 24,...

  7. Developing a scalable modeling architecture for studying survivability technologies

    Science.gov (United States)

    Mohammad, Syed; Bounker, Paul; Mason, James; Brister, Jason; Shady, Dan; Tucker, David

    2006-05-01

    To facilitate interoperability of models in a scalable environment, and provide a relevant virtual environment in which Survivability technologies can be evaluated, the US Army Research Development and Engineering Command (RDECOM) Modeling Architecture for Technology Research and Experimentation (MATREX) Science and Technology Objective (STO) program has initiated the Survivability Thread which will seek to address some of the many technical and programmatic challenges associated with the effort. In coordination with different Thread customers, such as the Survivability branches of various Army labs, a collaborative group has been formed to define the requirements for the simulation environment that would in turn provide them a value-added tool for assessing models and gauge system-level performance relevant to Future Combat Systems (FCS) and the Survivability requirements of other burgeoning programs. An initial set of customer requirements has been generated in coordination with the RDECOM Survivability IPT lead, through the Survivability Technology Area at RDECOM Tank-automotive Research Development and Engineering Center (TARDEC, Warren, MI). The results of this project are aimed at a culminating experiment and demonstration scheduled for September, 2006, which will include a multitude of components from within RDECOM and provide the framework for future experiments to support Survivability research. This paper details the components with which the MATREX Survivability Thread was created and executed, and provides insight into the capabilities currently demanded by the Survivability faculty within RDECOM.

  8. Determining the Optimal Number of Core Needle Biopsy Passes for Molecular Diagnostics.

    Science.gov (United States)

    Hoang, Nam S; Ge, Benjamin H; Pan, Lorraine Y; Ozawa, Michael G; Kong, Christina S; Louie, John D; Shah, Rajesh P

    2018-03-01

    The number of core biopsy passes required for adequate next-generation sequencing is impacted by needle cut, needle gauge, and the type of tissue involved. This study evaluates diagnostic adequacy of core needle lung biopsies based on number of passes and provides guidelines for other tissues based on simulated biopsies in ex vivo porcine organ tissues. The rate of diagnostic adequacy for pathology and molecular testing from lung biopsy procedures was measured for eight operators pre-implementation (September 2012-October 2013) and post-implementation (December 2013-April 2014) of a standard protocol using 20-gauge side-cut needles for ten core biopsy passes at a single academic hospital. Biopsy pass volume was then estimated in ex vivo porcine muscle, liver, and kidney using side-cut devices at 16, 18, and 20 gauge and end-cut devices at 16 and 18 gauge to estimate minimum number of passes required for adequate molecular testing. Molecular diagnostic adequacy increased from 69% (pre-implementation period) to 92% (post-implementation period) (p < 0.001) for lung biopsies. In porcine models, both 16-gauge end-cut and side-cut devices require one pass to reach the validated volume threshold to ensure 99% adequacy for molecular characterization, while 18- and 20-gauge devices require 2-5 passes depending on needle cut and tissue type. Use of 20-gauge side-cut core biopsy needles requires a significant number of passes to ensure diagnostic adequacy for molecular testing across all tissue types. To ensure diagnostic adequacy for molecular testing, 16- and 18-gauge needles require markedly fewer passes.

  9. Own-Brand and Cross-Brand Retail Pass-Through

    OpenAIRE

    David Besanko; Jean-Pierre Dubé; Sachin Gupta

    2005-01-01

    In this paper we describe the pass-through behavior of a major U.S. supermarket chain for 78 products across 11 categories. Our data set includes retail prices and wholesale prices for stores in 15 retail price zones for a one-year period. For the empirical model, we use a reduced-form approach that focuses directly on equilibrium prices as a function of exogenous supply- and demand-shifting variables. The reduced-form approach enables us to identify the theoretical pass-through rate without ...

  10. Generalizing Galileo's Passe-Dix Game

    Science.gov (United States)

    Hombas, Vassilios

    2012-01-01

    This article shows a generalization of Galileo's "passe-dix" game. The game was born following one of Galileo's [G. Galileo, "Sopra le Scoperte dei Dadi" (Galileo, Opere, Firenze, Barbera, Vol. 8). Translated by E.H. Thorne, 1898, pp. 591-594] explanations on a paradox that occurred in the experiment of tossing three fair "six-sided" dice.…

  11. Two-pass greedy regular expression parsing

    DEFF Research Database (Denmark)

    Grathwohl, Niels Bjørn Bugge; Henglein, Fritz; Nielsen, Lasse

    2013-01-01

    We present new algorithms for producing greedy parses for regular expressions (REs) in a semi-streaming fashion. Our lean-log algorithm executes in time O(mn) for REs of size m and input strings of size n and outputs a compact bit-coded parse tree representation. It improves on previous algorithms...... by: operating in only 2 passes; using only O(m) words of random-access memory (independent of n); requiring only kn bits of sequentially written and read log storage, where k ... and not requiring it to be stored at all. Previous RE parsing algorithms do not scale linearly with input size, or require substantially more log storage and employ 3 passes where the first consists of reversing the input, or do not or are not known to produce a greedy parse. The performance of our unoptimized C...

  12. Analysis of CMOS Compatible Cu-Based TM-Pass Optical Polarizer

    KAUST Repository

    Ng, Tien Khee

    2012-02-10

    A transverse-magnetic-pass (TM-pass) optical polarizer based on Cu complementary metal-oxide-semiconductor technology platform is proposed and analyzed using the 2-D method-of-lines numerical model. In designing the optimum configuration for the polarizer, it was found that the metal-insulator-metal (MIM) polarizer structure is superior compared to the insulator-metal-insulator polarizer structure due to its higher polarization extinction ratio (PER) and low insertion loss. An optimized MIM TM-pass polarizer exhibits simulated long wavelength pass filter characteristics of > ?1.2 ?m, with fundamental TM 0 and TE 0 mode transmissivity of >70% and <5%, respectively, and with PER ?11.5 dB in the wavelength range of 1.2-1.6 ?m. The subwavelength and submicrometer features of this TM-polarizer are potentially suitable for compact and low power photonics integrated circuit implementation on silicon-based substrates. © 1989-2012 IEEE.

  13. Bacillus sp. LT3 improves the survival of gnotobiotic brine shrimp (Artemia franciscana) larvae challenged with Vibrio campbellii by enhancing the innate immune response and by decreasing the activity of shrimp-associated vibrios.

    Science.gov (United States)

    Niu, Yufeng; Defoirdt, Tom; Baruah, Kartik; Van de Wiele, Tom; Dong, Shuanglin; Bossier, Peter

    2014-10-10

    Bacteria belonging to the genus Bacillus are amongst the most intensively studied group of bacteria for use as probiotics in aquaculture. However, the exact mechanism of action of these bacteria is often not well described, and the microbiota that are naturally present in cultures of test organisms often compromise the interpretation of the results. The present study aimed to evaluate the putative probiotic effect of Bacillus sp. LT3 in a model system with gnotobiotic brine shrimp Artemia franciscana larvae. The strain significantly increased the survival of brine shrimp larvae challenged with Vibrio campbellii when administered 6h before the challenge. Under these conditions, LT3 was able to colonize the brine shrimp gastrointestinal tract and to decrease the in vivo pathogen activity as indicated by the bioluminescence of the V. campbellii associated with brine shrimp larvae. In order to investigate the effect of the Bacillus strain on the innate immune system of the brine shrimp larvae, prophenoloxidase and transglutaminase mRNA levels were monitored, while heat shock protein 70 mRNA levels were measured as an indicator of physiological stress. Interestingly, 12h after challenge, the prophenoloxidase mRNA level in the larvae pre-treated with LT3 and challenged with V. campbellii was approximately 8-fold higher than in the other treatments. Further, a decreased mRNA level of transglutaminase gene and heat shock protein 70 gene suggested that pretreatment with LT3 results in less stress and tissue damage in the brine shrimp larvae upon V. campbellii challenge. These results indicated that Bacillus sp. LT3 could improve the survival of brine shrimp larvae when challenged with pathogenic V. campbellii, both by decreasing the in vivo activity of the pathogen and by priming the innate immune response through activating the prophenoloxidase system. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. How to pass higher English colour

    CERN Document Server

    Bridges, Ann

    2009-01-01

    How to Pass is the Number 1 revision series for Scottish qualifications across the three examination levels of Standard Grade, Intermediate and Higher! Second editions of the books present all of the material in full colour for the first time.

  15. JEMMRLA - Electron Model of a Muon RLA with Multi-pass Arcs

    Energy Technology Data Exchange (ETDEWEB)

    Bogacz, Slawomir Alex; Krafft, Geoffrey A.; Morozov, Vasiliy S.; Roblin, Yves R.

    2013-06-01

    We propose a demonstration experiment for a new concept of a 'dogbone' RLA with multi-pass return arcs -- JEMMRLA (Jlab Electron Model of Muon RLA). Such an RLA with linear-field multi-pass arcs was introduced for rapid acceleration of muons for the next generation of Muon Facilities. It allows for efficient use of expensive RF while the multi-pass arc design based on linear combined-function magnets exhibits a number of advantages over separate-arc or pulsed-arc designs. Here we describe a test of this concept by scaling a GeV scale muon design for electrons. Scaling muon momenta by the muon-to-electron mass ratio leads to a scheme, in which a 4.5 MeV electron beam is injected in the middle of a 3 MeV/pass linac with two double-pass return arcs and is accelerated to 18 MeV in 4.5 passes. All spatial dimensions including the orbit distortion are scaled by a factor of 7.5, which arises from scaling the 200 MHz muon RF to a readily available 1.5 GHz. The hardware requirements are not very demanding making it straightforward to implement. Such an RLA may have applications going beyond muon acceleration: in medical isotope production, radiation cancer therapy and homeland security.

  16. Performance of single-pass and by-pass multi-step multi-soil-layering systems for low-(C/N)-ratio polluted river water treatment.

    Science.gov (United States)

    Wei, Cai-Jie; Wu, Wei-Zhong

    2018-09-01

    Two kinds of hybrid two-step multi-soil-layering (MSL) systems loaded with different filter medias (zeolite-ceramsite MSL-1 and ceramsite-red clay MSL-2) were set-up for the low-(C/N)-ratio polluted river water treatment. A long-term pollutant removal performance of these two kinds of MSL systems was evaluated for 214 days. By-pass was employed in MSL systems to evaluate its effect on nitrogen removal enhancement. Zeolite-ceramsite single-pass MSL-1 system owns outstanding ammonia removal capability (24 g NH 4 + -Nm -2 d -1 ), 3 times higher than MSL-2 without zeolite under low aeration rate condition (0.8 × 10 4  L m -2 .h -1 ). Aeration rate up to 1.6 × 10 4  L m -2 .h -1 well satisfied the requirement of complete nitrification in first unit of both two MSLs. However, weak denitrification in second unit was commonly observed. By-pass of 50% influent into second unit can improve about 20% TN removal rate for both MSL-1 and MSL-2. Complete nitrification and denitrification was achieved in by-pass MSL systems after addition of carbon source with the resulting C/N ratio up to 2.5. The characters of biofilms distributed in different sections inside MSL-1 system well illustrated the nitrogen removal mechanism inside MSL systems. Two kinds of MSLs are both promising as an appealing nitrifying biofilm reactor. Recirculation can be considered further for by-pass MSL-2 system to ensure a complete ammonia removal. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. 26 CFR 20.2056A-1 - Restrictions on allowance of marital deduction if surviving spouse is not a United States citizen.

    Science.gov (United States)

    2010-04-01

    ... tax marital deduction is not allowed for property passing to or for the benefit of a surviving spouse..., inheritance, or gift taxes, the amendments made by section 5033 of the Technical and Miscellaneous Revenue Act... inconsistent with the provisions of such treaty relating to estate, inheritance, or gift tax marital deductions...

  18. Visualization of mcr mRNA in a methanogen by fluorescence in situ hybridization with an oligonucleotide probe and two-pass tyramide signal amplification (two-pass TSA-FISH).

    Science.gov (United States)

    Kubota, Kengo; Ohashi, Akiyoshi; Imachi, Hiroyuki; Harada, Hideki

    2006-09-01

    Two-pass tyramide signal amplification-fluorescence in situ hybridization (two-pass TSA-FISH) with a horseradish peroxidase (HRP)-labeled oligonucleotide probe was applied to detect prokaryotic mRNA. In this study, mRNA of a key enzyme for methanogenesis, methyl coenzyme M reductase (mcr), in Methanococcus vannielii was targeted. Applicability of mRNA-targeted probes to in situ hybridization was verified by Clone-FISH. It was observed that sensitivity of two-pass TSA-FISH was significantly higher than that of TSA-FISH, which was further increased by the addition of dextran sulphate in TSA working solution. Signals from two-pass TSA-FISH were more reliable compared to the weak, spotty signals yielded by TSA-FISH.

  19. Kaempferol and Chrysin Synergies to Improve Septic Mice Survival.

    Science.gov (United States)

    Harasstani, Omar A; Tham, Chau Ling; Israf, Daud A

    2017-01-06

    Previously, we reported the role of synergy between two flavonoids-namely, chrysin and kaempferol-in inhibiting the secretion of a few major proinflammatory mediators such as tumor necrosis factor -alpha (TNF-α), prostaglandin E₂ (PGE₂) , and nitric oxide (NO) from lipopolysaccharide (LPS)-induced RAW 264.7 cells. The present study aims to evaluate the effects of this combination on a murine model of polymicrobial sepsis induced by cecal ligation and puncture (CLP). Severe sepsis was induced in male ICR mice ( n = 7) via the CLP procedure. The effects of chrysin and kaempferol combination treatment on septic mice were investigated using a 7-day survival study. The levels of key proinflammatory mediators and markers-such as aspartate aminotransferase (AST), TNF-α, and NO-in the sera samples of the septic mice were determined via ELISA and fluorescence determination at different time point intervals post-CLP challenge. Liver tissue samples from septic mice were harvested to measure myeloperoxidase (MPO) levels using a spectrophotometer. Moreover, intraperitoneal fluid (IPF) bacterial clearance and total leukocyte count were also assessed to detect any antibacterial effects exerted by chrysin and kaempferol, individually and in combination. Kaempferol treatment improved the survival rate of CLP-challenged mice by up to 16%. During this treatment, kaempferol expressed antibacterial, antiapoptotic and antioxidant activities through the attenuation of bacterial forming units, AST and NO levels, and increased polymorphonuclear leukocyte (PMN) count in the IPF. On the other hand, the chrysin treatment significantly reduced serum TNF-α levels. However, it failed to significantly improve the survival rate of the CLP-challenged mice. Subsequently, the kaempferol/chrysin combination treatment significantly improved the overall 7-day survival rate by 2-fold-up to 29%. Kaempferol and chrysin revealed some synergistic effects by acting individually upon multiple

  20. Message passing with parallel queue traversal

    Science.gov (United States)

    Underwood, Keith D [Albuquerque, NM; Brightwell, Ronald B [Albuquerque, NM; Hemmert, K Scott [Albuquerque, NM

    2012-05-01

    In message passing implementations, associative matching structures are used to permit list entries to be searched in parallel fashion, thereby avoiding the delay of linear list traversal. List management capabilities are provided to support list entry turnover semantics and priority ordering semantics.

  1. The Cushing OK Crude Oil Futures Price Pass - Through to New York Harbor Reformulated RBOB Regular Gasoline Futures Price

    Directory of Open Access Journals (Sweden)

    Chu V. Nguyen

    2017-04-01

    Full Text Available This study utilizes an Autoregressive Distributed Lag model to investigate the nature of crude oil futures price pass-through since 2006. The empirical results reveal a very high but incomplete short-run pass-through rate from the crude oil futures price to the gasoline futures price of 0.849298 with a corresponding negative long-run pass-through rate of -0.2440894. These empirical findings suggest that traders in the U.S. oil and gasoline futures markets overreact to fluctuations in the crude oil futures price as evidenced by subsequent corrections made over the sample period. The result of the bounds test for a long-term relationship between these two futures prices is inconclusive. The empirical findings further suggest that U.S. futures market traders considered futures prices of gasoline three weeks earlier in determining the current trading price while taking only one week to respond completely to the shock in the crude oil futures price.  The empirical findings of this investigation may address the core elements of the price dynamics of the crude oil and gasoline futures markets and advance inquiry into assessment tools that could manage a very complex market challenge, especially for policy makers in countries with transitional economies in Eastern Europe, Caucasus and Central Asia.

  2. A multi-year analysis of spillway survival for juvenile salmonids as a function of spill bay operations at McNary Dam, Washington and Oregon, 2004-09

    Science.gov (United States)

    Adams, Noah S.; Hansel, Hal C.; Perry, Russell W.; Evans, Scott D.

    2012-01-01

    We analyzed 6 years (2004-09) of passage and survival data collected at McNary Dam to examine how spill bay operations affect survival of juvenile salmonids passing through the spillway at McNary Dam. We also examined the relations between spill bay operations and survival through the juvenile fish bypass in an attempt to determine if survival through the bypass is influenced by spill bay operations. We used a Cormack-Jolly-Seber release-recapture model (CJS model) to determine how the survival of juvenile salmonids passing through McNary Dam relates to spill bay operations. Results of these analyses, while not designed to yield predictive models, can be used to help develop dam-operation strategies that optimize juvenile salmonid survival. For example, increasing total discharge typically had a positive effect on both spillway and bypass survival for all species except sockeye salmon (Oncorhynchus nerka). Likewise, an increase in spill bay discharge improved spillway survival for yearling Chinook salmon (Oncorhynchus tshawytscha), and an increase in spillway discharge positively affected spillway survival for juvenile steelhead (Oncorhynchus mykiss). The strong linear relation between increased spill and increased survival indicates that increasing the amount of water through the spillway is one strategy that could be used to improve spillway survival for yearling Chinook salmon and juvenile steelhead. However, increased spill did not improve spillway survival for subyearling Chinook salmon and sockeye salmon. Our results indicate that a uniform spill pattern would provide the highest spillway survival and bypass survival for subyearling Chinook salmon. Conversely, a predominantly south spill pattern provided the highest spillway survival for yearling Chinook salmon and juvenile steelhead. Although spill pattern was not a factor for spillway survival of sockeye salmon, spill bay operations that optimize passage through the north and south spill bays maximized

  3. Derivation of Oscillators from Biquadratic Band Pass Filters Using Circuit Transformations

    Directory of Open Access Journals (Sweden)

    Hung-Yu Wang

    2014-09-01

    Full Text Available Network transformations are the techniques to obtain new functional schemes from available circuits. They are systematic methodologies, since each transformation technique can be applied to many circuits to obtain the desired functions or characteristics. A convenient network transformation method, exploiting different circuit transformations, for deriving linear sinusoidal oscillators from biquadratic band pass filters is proposed. This method with generality can be applied to any band pass filter. The oscillation frequency of the new obtained oscillator is identical to the center frequency of the original band pass filter, and the useful properties of the selected band pass filter can be retained. Two examples are illustrated to confirm the feasibility of the proposed approach. The workability of the obtained oscillators is verified with PSPICE simulations.

  4. Delay Bound: Fractal Traffic Passes through Network Servers

    Directory of Open Access Journals (Sweden)

    Ming Li

    2013-01-01

    Full Text Available Delay analysis plays a role in real-time systems in computer communication networks. This paper gives our results in the aspect of delay analysis of fractal traffic passing through servers. There are three contributions presented in this paper. First, we will explain the reasons why conventional theory of queuing systems ceases in the general sense when arrival traffic is fractal. Then, we will propose a concise method of delay computation for hard real-time systems as shown in this paper. Finally, the delay computation of fractal traffic passing through severs is presented.

  5. Serial killers, spiders and cybersex: Social and survival information bias in the transmission of urban legends.

    Science.gov (United States)

    Stubbersfield, Joseph M; Tehrani, Jamshid J; Flynn, Emma G

    2015-05-01

    This study uses urban legends to examine the effects of the social information bias and survival information bias on cultural transmission across three phases of transmission: the choose-to-receive phase, the encode-and-retrieve phase, and the choose-to-transmit phase. In line with previous research into content biases, a linear transmission chain design with 60 participants aged 18-52 was used to examine the encode-and-retrieve phase, while participants were asked to rank their interest in reading the story behind a headline and passing a story on for the other two phases. Legends which contained social information (Social Type), legends which contained survival information (Survival Type), and legends which contained both forms of information (Combined Type) were all recalled with significantly greater accuracy than control material, while Social and Combined Type legends were recalled with significantly greater accuracy than Survival Type legends. In another study with 30 participants aged 18-22, no significant differences were found between legend types in either the choose-to-receive phase or the choose-to-transmit phase. © 2014 The British Psychological Society.

  6. Setting and validating the pass/fail score for the NBDHE.

    Science.gov (United States)

    Tsai, Tsung-Hsun; Dixon, Barbara Leatherman

    2013-04-01

    This report describes the overall process used for setting the pass/fail score for the National Board Dental Hygiene Examination (NBDHE). The Objective Standard Setting (OSS) method was used for setting the pass/fail score for the NBDHE. The OSS method requires a panel of experts to determine the criterion items and proportion of these items that minimally competent candidates would answer correctly, the percentage of mastery and the confidence level of the error band. A panel of 11 experts was selected by the Joint Commission on National Dental Examinations (Joint Commission). Panel members represented geographic distribution across the U.S. and had the following characteristics: full-time dental hygiene practitioners with experience in areas of preventive, periodontal, geriatric and special needs care, and full-time dental hygiene educators with experience in areas of scientific basis for dental hygiene practice, provision of clinical dental hygiene services and community health/research principles. Utilizing the expert panel's judgments, the pass/fail score was set and then the score scale was established using the Rasch measurement model. Statistical and psychometric analysis shows the actual failure rate and the OSS failure rate are reasonably consistent (2.4% vs. 2.8%). The analysis also showed the lowest error of measurement, an index of the precision at the pass/fail score point and that the highest reliability (0.97) are achieved at the pass/fail score point. The pass/fail score is a valid guide for making decisions about candidates for dental hygiene licensure. This new standard was reviewed and approved by the Joint Commission and was implemented beginning in 2011.

  7. The Physical Therapy and Society Summit (PASS) Meeting: observations and opportunities.

    Science.gov (United States)

    Kigin, Colleen M; Rodgers, Mary M; Wolf, Steven L

    2010-11-01

    The construct of delivering high-quality and cost-effective health care is in flux, and the profession must strategically plan how to meet the needs of society. In 2006, the House of Delegates of the American Physical Therapy Association passed a motion to convene a summit on "how physical therapists can meet current, evolving, and future societal health care needs." The Physical Therapy and Society Summit (PASS) meeting on February 27-28, 2009, in Leesburg, Virginia, sent a clear message that for physical therapists to be effective and thrive in the health care environment of the future, a paradigm shift is required. During the PASS meeting, participants reframed our traditional focus on the physical therapist and the patient/client (consumer) to one in which physical therapists are an integral part of a collaborative, multidisciplinary health care team with the health care consumer as its focus. The PASS Steering Committee recognized that some of the opportunities that surfaced during the PASS meeting may be disruptive or may not be within the profession's present strategic or tactical plans. Thus, adopting a framework that helps to establish the need for change that is provocative and potentially disruptive to our present care delivery, yet prioritizes opportunities, is a critical and essential step. Each of us in the physical therapy profession must take on post-PASS roles and responsibilities to accomplish the systemic change that is so intimately intertwined with our destiny. This article offers a perspective of the dynamic dialogue and suggestions that emerged from the PASS event, providing further opportunities for discussion and action within our profession.

  8. The thermal performance of the two-pass, two-glass-cover solar air heater

    Energy Technology Data Exchange (ETDEWEB)

    Persad, P.; Sateunanathan, S.

    1983-08-01

    Analytic models are developed for the performance prediction of a two-glass-cover solar air heater operated in both the single-pass and two-pass modes. It is shown that the two-pass mode of operation is superior to the single-pass mode of operation over the range of collector inlet temperatures considered. This is seen to be mainly due to the fact that, in the two-pass mode of operation, the outer glass cover is cooled by the working fluid, thereby reducing the top losses. It is also shown that the performance in the two-pass mode of operation is independent of length, over the range of collector lengths considered, and that a critical plate spacing, dependent on the temperature level of operation of the collector, is indicated. Predicted values of performance are in good agreement with experimental results.

  9. Reversible wavelet filter banks with side informationless spatially adaptive low-pass filters

    Science.gov (United States)

    Abhayaratne, Charith

    2011-07-01

    Wavelet transforms that have an adaptive low-pass filter are useful in applications that require the signal singularities, sharp transitions, and image edges to be left intact in the low-pass signal. In scalable image coding, the spatial resolution scalability is achieved by reconstructing the low-pass signal subband, which corresponds to the desired resolution level, and discarding other high-frequency wavelet subbands. In such applications, it is vital to have low-pass subbands that are not affected by smoothing artifacts associated with low-pass filtering. We present the mathematical framework for achieving 1-D wavelet transforms that have a spatially adaptive low-pass filter (SALP) using the prediction-first lifting scheme. The adaptivity decisions are computed using the wavelet coefficients, and no bookkeeping is required for the perfect reconstruction. Then, 2-D wavelet transforms that have a spatially adaptive low-pass filter are designed by extending the 1-D SALP framework. Because the 2-D polyphase decompositions are used in this case, the 2-D adaptivity decisions are made nonseparable as opposed to the separable 2-D realization using 1-D transforms. We present examples using the 2-D 5/3 wavelet transform and their lossless image coding and scalable decoding performances in terms of quality and resolution scalability. The proposed 2-D-SALP scheme results in better performance compared to the existing adaptive update lifting schemes.

  10. The effect of radiotherapy on dysphagia and survival in patients with esophageal cancer

    International Nuclear Information System (INIS)

    Caspers, R.J.L.; Leer, J.W.H.; Welvaart, K.; Verkes, R.J.; Hermans, J.

    1988-01-01

    A group of 127 patients with esophageal cancer treated with radiotherapy at different dose levels was retrospectively analysed. It was found that 70.5% of the patients showed improvement of dysphagia and that 54% remained palliated with respect to food passage until their death. The two major prognostic variables with respect to the palliative effect on dysphagia as well as survival were the passage score and the radiation dose. Patients with severe dysphagia (PASS 0 or 1) had a median actuarial DFI and SURV of 3.7 and 6.4 months, respectively, in contrast to 16.0 and 8.7 months for patients who were able to use (semi)solid food (PASS 2 or 3). The median actuarial DFI and SURV of patients treated with a relatively low dose (less than 50 Gy in 5 weeks) were 2.5 and 4.8 months, respectively, compared to 10.1 and 8.3 months, respectively, for patients treated with a relatively high dose. 17 refs.; 4 figs.; 7 tabs

  11. Current Challenges in Cancer Treatment.

    Science.gov (United States)

    Zugazagoitia, Jon; Guedes, Cristiano; Ponce, Santiago; Ferrer, Irene; Molina-Pinelo, Sonia; Paz-Ares, Luis

    2016-07-01

    In this review, we highlight the current concepts and discuss some of the current challenges and future prospects in cancer therapy. We frequently use the example of lung cancer. We conducted a nonsystematic PubMed search, selecting the most comprehensive and relevant research articles, clinical trials, translational papers, and review articles on precision oncology and immuno-oncology. Papers were prioritized and selected based on their originality and potential clinical applicability. Two major revolutions have changed cancer treatment paradigms in the past few years: targeting actionable alterations in oncogene-driven cancers and immuno-oncology. Important challenges are still ongoing in both fields of cancer therapy. On the one hand, druggable genomic alterations are diverse and represent only small subsets of patients in certain tumor types, which limits testing their clinical impact in biomarker-driven clinical trials. Next-generation sequencing technologies are increasingly being implemented for molecular prescreening in clinical research, but issues regarding clinical interpretation of large genomic data make their wide clinical use difficult. Further, dealing with tumor heterogeneity and acquired resistance is probably the main limitation for the success of precision oncology. On the other hand, long-term survival benefits with immune checkpoint inhibitors (anti-programmed death cell protein-1/programmed death cell ligand-1[PD-1/L1] and anti-cytotoxic T lymphocyte antigen-4 monoclonal antibodies) are restricted to a minority of patients, and no predictive markers are yet robustly validated that could help us recognize these subsets and optimize treatment delivery and selection. To achieve long-term survival benefits, drug combinations targeting several molecular alterations or cancer hallmarks might be needed. This will probably be one of the most challenging but promising precision cancer treatment strategies in the future. Targeting single molecular

  12. TREsPASS Book 3: Creative Engagements

    NARCIS (Netherlands)

    Coles-Kemp, Lizzie; Hall, Peter

    2016-01-01

    In this book we examine the role that creative security engagements have played in the TREsPASS project. These engagements are part of a wider creative securities approach that explores the contributions that social practices make to protection of data and information. Our most popular creative

  13. Speech overlap detection in a two-pass speaker diarization system

    NARCIS (Netherlands)

    Huijbregts, M.A.H.; Leeuwen, D.A. van; Jong, F. M. G de

    2009-01-01

    In this paper we present the two-pass speaker diarization system that we developed for the NIST RT09s evaluation. In the first pass of our system a model for speech overlap detection is gen- erated automatically. This model is used in two ways to reduce the diarization errors due to overlapping

  14. Speech overlap detection in a two-pass speaker diarization system

    NARCIS (Netherlands)

    Huijbregts, M.; Leeuwen, D.A. van; Jong, F.M.G. de

    2009-01-01

    In this paper we present the two-pass speaker diarization system that we developed for the NIST RT09s evaluation. In the first pass of our system a model for speech overlap detection is generated automatically. This model is used in two ways to reduce the diarization errors due to overlapping

  15. EXPERIMENTAL CHALLENGE STUDY OF FV3-LIKE RANAVIRUS INFECTION IN PREVIOUSLY FV3-LIKE RANAVIRUS INFECTED EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA) TO ASSESS INFECTION AND SURVIVAL.

    Science.gov (United States)

    Hausmann, Jennifer C; Wack, Allison N; Allender, Matthew C; Cranfield, Mike R; Murphy, Kevin J; Barrett, Kevin; Romero, Jennell L; Wellehan, James F X; Blum, Stella A; Zink, M Christine; Bronson, Ellen

    2015-12-01

    The Maryland Zoo in Baltimore experienced an outbreak of Frog virus-3 (FV3)-like ranavirus during the summer of 2011, during which 14 of 27 (52%) of its captive eastern box turtles (Terrapene carolina carolina) survived. To assess survival, immunity, and viral shedding, an experimental challenge study was performed in which the surviving, previously infected turtles were reinfected with the outbreak strain of FV3-like ranavirus. Seven turtles were inoculated with virus intramuscularly and four control turtles received saline intramuscularly. The turtles were monitored for 8 wk with blood and oral swabs collected for quantitative polymerase chain reaction (qPCR). During that time, one of seven (14%) inoculated turtles and none of the controls (0%) died; there was no significant difference in survival. Clinical signs of the inoculated turtles, except for the turtle that died, were mild compared to the original outbreak. Quantitative PCR for FV3-like ranavirus on blood and oral swabs was positive for all inoculated turtles and negative for all controls. The turtle that died had intracytoplasmic inclusion bodies in multiple organs. Three inoculated and two control turtles were euthanized at the end of the study. No inclusion bodies were present in any of the organs. Quantitative PCR detected FV3-like ranavirus in the spleen of a control turtle, which suggested persistence of the virus. The surviving five turtles were qPCR-negative for FV3-like ranavirus from blood and oral swabs after brumation. Quantitative PCR for Terrapene herpesvirus 1 found no association between ranavirus infection and herpesvirus loads. In conclusion, previously infected eastern box turtles can be reinfected with the same strain of FV3-like ranavirus and show mild to no clinical signs but can shed the virus from the oral cavity.

  16. Pass-through of Change in Policy Interest Rate to Market Rates

    OpenAIRE

    M. Idrees Khawaja; Sajawal Khan

    2008-01-01

    This paper examines the pass through of the change in policy interest rate of the central bank of Pakistan to market interest rates. The market rates examined include KIBOR, six month deposit rate and weighted average lending rate. More or less complete pass-through of the change in policy rate to KIBOR is observed within one month. However, the magnitude of change in policy rate to deposit and lending rate is not only low but is slow as well. The pass-through to the weighted average lending ...

  17. Effects of multi-pass arc welding on mechanical properties of carbon steel C25 plate

    International Nuclear Information System (INIS)

    Adedayo, S.M.; Babatunde, A.S.

    2013-01-01

    The effects of multi-pass welding on mechanical properties of C25 carbon steel plate were examined. Mild steel plate workpieces of 90 x 55 mm 2 area and 10 mm thickness with a 30 degrees vee weld-grooves were subjected to single and multi-pass welding. Toughness, hardness and tensile tests of single and multi-pass welds were conducted. Toughness values of the welds under double pass welds were higher than both single pass and unwelded alloy, at respective maximum values of 2464, 2342 and 2170 kN/m. Hardness values were reduced under double pass relative to single pass welding with both being lower than the value for unwelded alloy; the values were 40.5, 43.2 and 48.5 Rs respectively at 12 mm from the weld line. The tensile strength of 347 N/mm 2 under multi-pass weld was higher than single pass weld with value of 314 N/mm 2 . Therefore, the temperature distribution and apparent pre-heating during multi-pass welding increased the toughness and tensile strength of the weldments, but reduced the hardness. (au)

  18. A Message-Passing Hardware/Software Cosimulation Environment for Reconfigurable Computing Systems

    Directory of Open Access Journals (Sweden)

    Manuel Saldaña

    2009-01-01

    Full Text Available High-performance reconfigurable computers (HPRCs provide a mix of standard processors and FPGAs to collectively accelerate applications. This introduces new design challenges, such as the need for portable programming models across HPRCs and system-level verification tools. To address the need for cosimulating a complete heterogeneous application using both software and hardware in an HPRC, we have created a tool called the Message-passing Simulation Framework (MSF. We have used it to simulate and develop an interface enabling an MPI-based approach to exchange data between X86 processors and hardware engines inside FPGAs. The MSF can also be used as an application development tool that enables multiple FPGAs in simulation to exchange messages amongst themselves and with X86 processors. As an example, we simulate a LINPACK benchmark hardware core using an Intel-FSB-Xilinx-FPGA platform to quickly prototype the hardware, to test the communications. and to verify the benchmark results.

  19. Exposure to bacterial signals does not alter pea aphids' survival upon a second challenge or investment in production of winged offspring.

    Directory of Open Access Journals (Sweden)

    Bas ter Braak

    Full Text Available Pea aphids have an obligate nutritional symbiosis with the bacteria Buchneraaphidicola and frequently also harbor one or more facultative symbionts. Aphids are also susceptible to bacterial pathogen infections, and it has been suggested that aphids have a limited immune response towards such pathogen infections compared to other, more well-studied insects. However, aphids do possess at least some of the genes known to be involved in bacterial immune responses in other insects, and immune-competent hemocytes. One possibility is that immune priming with microbial elicitors could stimulate immune protection against subsequent bacterial infections, as has been observed in several other insect systems. To address this hypothesis we challenged aphids with bacterial immune elicitors twenty-four hours prior to live bacterial pathogen infections and then compared their survival rates to aphids that were not pre-exposed to bacterial signals. Using two aphid genotypes, we found no evidence for immune protection conferred by immune priming during infections with either Serratia marcescens or with Escherichia coli. Immune priming was not altered by the presence of facultative, beneficial symbionts in the aphids. In the absence of inducible immune protection, aphids may allocate energy towards other defense traits, including production of offspring with wings that could escape deteriorating conditions. To test this, we monitored the ratio of winged to unwinged offspring produced by adult mothers of a single clone that had been exposed to bacterial immune elicitors, to live E. coli infections or to no challenge. We found no correlation between immune challenge and winged offspring production, suggesting that this mechanism of defense, which functions upon exposure to fungal pathogens, is not central to aphid responses to bacterial infections.

  20. Stream capture to form Red Pass, northern Soda Mountains, California

    Science.gov (United States)

    Miller, David; Mahan, Shannon

    2014-01-01

    Red Pass, a narrow cut through the Soda Mountains important for prehistoric and early historic travelers, is quite young geologically. Its history of downcutting to capture streams west of the Soda Mountains, thereby draining much of eastern Fort Irwin, is told by the contrast in alluvial fan sediments on either side of the pass. Old alluvial fan deposits (>500 ka) were shed westward off an intact ridge of the Soda Mountains but by middle Pleistocene time, intermediate-age alluvial fan deposits (~100 ka) were laid down by streams flowing east through the pass into Silurian Valley. The pass was probably formed by stream capture driven by high levels of groundwater on the west side. This is evidenced by widespread wetland deposits west of the Soda Mountains. Sapping and spring discharge into Silurian Valley over millennia formed a low divide in the mountains that eventually was overtopped and incised by a stream. Lessons include the importance of groundwater levels for stream capture and the relatively youthful appearance of this ~100-200 ka feature in the slowly changing Mojave Desert landscape.

  1. Survival without sequelae after prolonged cardiopulmonary resuscitation after electric shock.

    Science.gov (United States)

    Motawea, Mohamad; Al-Kenany, Al-Sayed; Hosny, Mostafa; Aglan, Omar; Samy, Mohamad; Al-Abd, Mohamed

    2016-03-01

    "Electrical shock is the physiological reaction or injury caused by electric current passing through the human body. It occurs upon contact of a human body part with any source of electricity that causes a sufficient current through the skin, muscles, or hair causing undesirable effects ranging from simple burns to death." Ventricular fibrillation is believed to be the most common cause of death after electrical shock. "The ideal duration of cardiac resuscitation is unknown. Typically prolonged cardiopulmonary resuscitation is associated with poor neurologic outcomes and reduced long term survival. No consensus statement has been made and traditionally efforts are usually terminated after 15-30 minutes." The case under discussion seems worthy of the somewhat detailed description given. It is for a young man who survived after 65 minutes after electrical shock (ES) after prolonged high-quality cardiopulmonary resuscitation (CPR), multiple defibrillations, and artificial ventilation without any sequelae. Early start of adequate chest compressions and close adherence to advanced cardiac life support protocols played a vital role in successful CPR.

  2. Bank Consolidation in Nigeria: Marketing Implications and Challenges for the Surviving Banks

    OpenAIRE

    IE Ernest

    2012-01-01

    The purpose of this paper is to explore the marketing implications of the Nigerian bank consolidation with a view to theorizing the marketing challenges which Third World countries wishing to embark on the same exercise should watch out for. The research used secondary data sources to expose the status of marketing in the pre-consolidation era and goes further to put forward the marketing implications and challenges of the exercise. Delivery of quality services, repositioning of brand identi...

  3. Experimental evidence for multi-pass extraction with a bent crystal

    CERN Document Server

    Dehning, Bernd; Fidecaro, Giuseppe; Gyr, Marcel; Herr, Werner; Klem, J T; Scandale, Walter; Vuagnin, G; Weisse, E; Weisz, S; Møller, S P; Uggerhøj, Erik; Freund, A; Hustache, R; Carboni, G; Bussa, M P; Tosello, F

    1996-01-01

    The feasibility of extracting particles from the halo of a circulating proton beam using a bent silicon crystal has been demonstrated experimentally at the SPS for a beam energy of 120 GeV. Presently studies are conducted to understand the extraction mechanisms and the measured efficiencies. In particular the contribution of multi-pass extraction, where the particles can pass through the crystal many times before being channelled and extracted, is investigated. In a recent experiment, using a crystal especially fabricated with a finite amorphous layer on its surface, it has been proven that multi-pass extraction plays an important role. The experiment is described and the implication for further studies are discussed.

  4. Pass-through of crude oil prices at different stages in Turkey

    Directory of Open Access Journals (Sweden)

    Fatih Akçelik

    2016-03-01

    Full Text Available This paper examines the degree of oil price pass-through to domestic prices at different stages of supply chain in Turkey. Our results, based on vector autoregressive models, point out that the pass-through to domestic motor fuel prices is considerably fast as expected and just one third of a change in crude oil prices is reflected to the motor fuel prices due to the high share of taxes on retail prices. On the other hand, it is shown that impact of oil prices on transport services takes a longer time compared to other domestic prices. Over the 2004–2014 period, estimates suggest that a 10% permanent change in the international crude oil prices is associated with a 0.42 percentage points change in consumer inflation at the end of one year. The final accumulated pass-through to consumer inflation reaches 0.50 percentage points. Moreover, the pass-through to producer prices is nearly twice as much as that to consumer prices. Findings also provide some evidence for a strengthening in oil price pass-through to consumer inflation over time, which might reflect the growing natural gas intensity of the economy.

  5. Passing particle toroidal precession induced by electric field in a tokamak

    International Nuclear Information System (INIS)

    Andreev, V. V.; Ilgisonis, V. I.; Sorokina, E. A.

    2013-01-01

    Characteristics of a rotation of passing particles in a tokamak with radial electric field are calculated. The expression for time-averaged toroidal velocity of the passing particle induced by the electric field is derived. The electric-field-induced additive to the toroidal velocity of the passing particle appears to be much smaller than the velocity of the electric drift calculated for the poloidal magnetic field typical for the trapped particle. This quantity can even have the different sign depending on the azimuthal position of the particle starting point. The unified approach for the calculation of the bounce period and of the time-averaged toroidal velocity of both trapped and passing particles in the whole volume of plasma column is presented. The results are obtained analytically and are confirmed by 3D numerical calculations of the trajectories of charged particles

  6. Passing particle toroidal precession induced by electric field in a tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, V. V. [Peoples' Friendship University of Russia, Ordzhonikidze St. 3, Moscow 117198 (Russian Federation); Ilgisonis, V. I.; Sorokina, E. A. [Peoples' Friendship University of Russia, Ordzhonikidze St. 3, Moscow 117198 (Russian Federation); NRC “Kurchatov Institute”, Kurchatov Sq. 1, Moscow 123182 (Russian Federation)

    2013-12-15

    Characteristics of a rotation of passing particles in a tokamak with radial electric field are calculated. The expression for time-averaged toroidal velocity of the passing particle induced by the electric field is derived. The electric-field-induced additive to the toroidal velocity of the passing particle appears to be much smaller than the velocity of the electric drift calculated for the poloidal magnetic field typical for the trapped particle. This quantity can even have the different sign depending on the azimuthal position of the particle starting point. The unified approach for the calculation of the bounce period and of the time-averaged toroidal velocity of both trapped and passing particles in the whole volume of plasma column is presented. The results are obtained analytically and are confirmed by 3D numerical calculations of the trajectories of charged particles.

  7. Incorporating Pass-Phrase Dependent Background Models for Text-Dependent Speaker verification

    DEFF Research Database (Denmark)

    Sarkar, Achintya Kumar; Tan, Zheng-Hua

    2018-01-01

    -dependent. We show that the proposed method significantly reduces the error rates of text-dependent speaker verification for the non-target types: target-wrong and impostor-wrong while it maintains comparable TD-SV performance when impostors speak a correct utterance with respect to the conventional system......In this paper, we propose pass-phrase dependent background models (PBMs) for text-dependent (TD) speaker verification (SV) to integrate the pass-phrase identification process into the conventional TD-SV system, where a PBM is derived from a text-independent background model through adaptation using...... the utterances of a particular pass-phrase. During training, pass-phrase specific target speaker models are derived from the particular PBM using the training data for the respective target model. While testing, the best PBM is first selected for the test utterance in the maximum likelihood (ML) sense...

  8. Talent in Female Gymnastics: a Survival Analysis Based upon Performance Characteristics.

    Science.gov (United States)

    Pion, J; Lenoir, M; Vandorpe, B; Segers, V

    2015-11-01

    This study investigated the link between the anthropometric, physical and motor characteristics assessed during talent identification and dropout in young female gymnasts. 3 cohorts of female gymnasts (n=243; 6-9 years) completed a test battery for talent identification. Performance-levels were monitored over 5 years of competition. Kaplan-Meier and Cox Proportional Hazards analyses were conducted to determine the survival rate and the characteristics that influence dropout respectively. Kaplan-Meier analysis indicated that only 18% of the female gymnasts that passed the baseline talent identification test survived at the highest competition level 5 years later. The Cox Proportional Hazards Model indicated that gymnasts with a score in the best quartile for a specific characteristic significantly increased chances of survival by 45-129%. These characteristics being: basic motor skills (129%), shoulder strength (96%), leg strength (53%) and 3 gross motor coordination items (45-73%). These results suggest that tests batteries commonly used for talent identification in young female gymnasts may also provide valuable insights into future dropout. Therefore, multidimensional test batteries deserve a prominent place in the selection process. The individual test results should encourage trainers to invest in an early development of basic physical and motor characteristics to prevent attrition. © Georg Thieme Verlag KG Stuttgart · New York.

  9. Shaping decisions in volleyball An ecological approach to decision-making in volleyball passing

    NARCIS (Netherlands)

    Barsingerhorn, Annemiek D.; Zaal, Frank T. J. M.; De Poel, Harjo J.; Pepping, Gert-Jan

    2013-01-01

    To extend research on decision-making in sport we addressed the choices volleyball-players are faced with in a simple volleyball pass-return task. We manipulated the distance that eight experienced volleyball players had to cover for successful ball passing, and mapped their passing technique (i.e.,

  10. Passage survival of juvenile steelhead, coho salmon, and Chinook salmon in Lake Scanewa and at Cowlitz Falls Dam, Cowlitz River, Washington, 2010–16

    Science.gov (United States)

    Liedtke, Theresa L.; Kock, Tobias J.; Hurst, William

    2018-04-03

    ) released upstream of Cowlitz Falls Dam moved downstream and passed the project; the remaining fish either remained upstream of the dam (37 percent) or were collected (11 percent). In 2015 and 2016, collection efficiencies at Cowlitz Falls Dam were abnormally high for juvenile steelhead and coho salmon, which resulted in few fish passing the dam. Seven percent of the tagged steelhead (40 fish) and 4 percent of the tagged coho salmon (18 fish) released upstream of the dam eventually passed the project, but these low numbers of fish precluded the estimation of meaningful survival estimates. Dam passage survival probability estimates for juvenile Chinook salmon were 0.828 in 2013 and 0.861 in 2014, lower than previously reported for turbine-specific passage Cowlitz Falls Dam.

  11. Pass-band reconfigurable spoof surface plasmon polaritons

    Science.gov (United States)

    Zhang, Hao Chi; He, Pei Hang; Gao, Xinxin; Tang, Wen Xuan; Cui, Tie Jun

    2018-04-01

    In this paper, we introduce a new scheme to construct the band-pass tunable filter based on the band-pass reconfigurable spoof surface plasmon polaritons (SPPs), whose cut-off frequencies at both sides of the passband can be tuned through changing the direct current (DC) bias of varactors. Compared to traditional technology (e.g. microstrip filters), the spoof SPP structure can provide more tight field confinement and more significant field enhancement, which is extremely valuable for many system applications. In order to achieve this scheme, we proposed a specially designed SPP filter integrated with varactors and DC bias feeding structure to support the spoof SPP passband reconfiguration. Furthermore, the full-wave simulated result verifies the outstanding performance on both efficiency and reconfiguration, which has the potential to be widely used in advanced intelligent systems.

  12. Complete hazard ranking to analyze right-censored data: An ALS survival study.

    Science.gov (United States)

    Huang, Zhengnan; Zhang, Hongjiu; Boss, Jonathan; Goutman, Stephen A; Mukherjee, Bhramar; Dinov, Ivo D; Guan, Yuanfang

    2017-12-01

    Survival analysis represents an important outcome measure in clinical research and clinical trials; further, survival ranking may offer additional advantages in clinical trials. In this study, we developed GuanRank, a non-parametric ranking-based technique to transform patients' survival data into a linear space of hazard ranks. The transformation enables the utilization of machine learning base-learners including Gaussian process regression, Lasso, and random forest on survival data. The method was submitted to the DREAM Amyotrophic Lateral Sclerosis (ALS) Stratification Challenge. Ranked first place, the model gave more accurate ranking predictions on the PRO-ACT ALS dataset in comparison to Cox proportional hazard model. By utilizing right-censored data in its training process, the method demonstrated its state-of-the-art predictive power in ALS survival ranking. Its feature selection identified multiple important factors, some of which conflicts with previous studies.

  13. PENGATURAN PASSING OFF DALAM PENGGUNAAN DOMAIN NAME TERKAIT DENGAN MEREK

    Directory of Open Access Journals (Sweden)

    Herti Yunita Putri

    2016-09-01

    Full Text Available In cyber world we often hear about domain name’s term. Domain name is a unique name to identify the server computer’s name like a web server or email server on a computer network or Internet. Passing off also make causes confusion in using merk from a famous brand or merk on the goods and services. Selected domain name in the internet media often creates the similar domain name with the other parties. This similar domain name are often used by people who are not responsible to take advantages of the domain name for themself. This can be caused by the presence of competition from Internet media business. This things called passing off. This research is a normative juridical research with a qualitative analysis. The legal materials include primary legal, secondary law and tertiary legal materials. Collection technique applied is literary study. Legal materials were analyzed to see the argument implementation of the definition of merk, the definition of domain name, definition of passing off, passing off in use related by merk and domain name and the rules of law in Indonesia related by merk, domain name and passing off. Big wishes in the future it can assist as a basic reference and legal considerations which are useful in Indonesian law practice. There are two passing off related to the merk and domain name, called Crybersquatting and Tiposquatting. Domain name rules are not regulated clearly in merk regulation named Act No. 15 of 2001. It regulated in PP 24 Year 1993 about The Class List of Goods or Services In Merk, Telecommunications are included in the goods or services in merk. Domain name are regulated in UDRP (Uniform Dispute Resolution Policy with competent institutions called ICANN (Internet Corporation for Assigned Names and Numbers. Dalam dunia maya (cyber world, kita sering mendengar istilah domain name. Domain name adalah nama unik yang diberikan untuk mengidentifikasi nama server komputer seperti web server atau email server di

  14. Introduction: Mirrors of Passing

    DEFF Research Database (Denmark)

    Seebach, Sophie Hooge; Willerslev, Rane

    How is death, time, and materiality interconnected? How to approach an understanding of the world of the dead? In this introduction, we seek to understand how the experience of material decay, of the death of those around us, makes us aware of the passing of time. Through the literary lens of Neil...... Gaiman’s The Graveyard Book, we explore how the world of the dead and the world of the living can intersect; how time and materiality shifts and changes depending on who experiences it. These revelations, based on fiction, provide a mirror through which the reader can experience the varied chapters...

  15. EXIT Chart Analysis of Binary Message-Passing Decoders

    DEFF Research Database (Denmark)

    Lechner, Gottfried; Pedersen, Troels; Kramer, Gerhard

    2007-01-01

    Binary message-passing decoders for LDPC codes are analyzed using EXIT charts. For the analysis, the variable node decoder performs all computations in the L-value domain. For the special case of a hard decision channel, this leads to the well know Gallager B algorithm, while the analysis can...... be extended to channels with larger output alphabets. By increasing the output alphabet from hard decisions to four symbols, a gain of more than 1.0 dB is achieved using optimized codes. For this code optimization, the mixing property of EXIT functions has to be modified to the case of binary message......-passing decoders....

  16. Standard setting in medical education: fundamental concepts and emerging challenges.

    Science.gov (United States)

    Mortaz Hejri, Sara; Jalili, Mohammad

    2014-01-01

    The process of determining the minimum pass level to separate the competent students from those who do not perform well enough is called standard setting. A large number of methods are widely used to set cut-scores for both written and clinical examinations. There are some challenging issues pertaining to any standard setting procedure. Ignoring these concerns would result in a large dispute regarding the credibility and defensibility of the method. The goal of this review is to provide a basic understanding of the key concepts and challenges in standard setting and to suggest some recommendations to overcome the challenging issues for educators and policymakers who are dealing with decision-making in this field.

  17. Double Pass 595?nm pulsed dye laser at a 6 minute interval for the treatment of port-wine stains is not more effective than single pass

    NARCIS (Netherlands)

    Peters, M. A. D.; van Drooge, A. M.; Wolkerstorfer, A.; van Gemert, M. J. C.; van der Veen, J. P. W.; Bos, J. D.; Beek, J. F.

    2012-01-01

    Background Pulsed dye laser (PDL) is the first choice for treatment of port wine stains (PWS). However, outcome is highly variable and only a few patients achieve complete clearance. The objective of the study was to compare efficacy and safety of single pass PDL with double pass PDL at a 6 minute

  18. Comparison of cryogenic low-pass filters

    Science.gov (United States)

    Thalmann, M.; Pernau, H.-F.; Strunk, C.; Scheer, E.; Pietsch, T.

    2017-11-01

    Low-temperature electronic transport measurements with high energy resolution require both effective low-pass filtering of high-frequency input noise and an optimized thermalization of the electronic system of the experiment. In recent years, elaborate filter designs have been developed for cryogenic low-level measurements, driven by the growing interest in fundamental quantum-physical phenomena at energy scales corresponding to temperatures in the few millikelvin regime. However, a single filter concept is often insufficient to thermalize the electronic system to the cryogenic bath and eliminate spurious high frequency noise. Moreover, the available concepts often provide inadequate filtering to operate at temperatures below 10 mK, which are routinely available now in dilution cryogenic systems. Herein we provide a comprehensive analysis of commonly used filter types, introduce a novel compact filter type based on ferrite compounds optimized for the frequency range above 20 GHz, and develop an improved filtering scheme providing adaptable broad-band low-pass characteristic for cryogenic low-level and quantum measurement applications at temperatures down to few millikelvin.

  19. Comparison of cryogenic low-pass filters.

    Science.gov (United States)

    Thalmann, M; Pernau, H-F; Strunk, C; Scheer, E; Pietsch, T

    2017-11-01

    Low-temperature electronic transport measurements with high energy resolution require both effective low-pass filtering of high-frequency input noise and an optimized thermalization of the electronic system of the experiment. In recent years, elaborate filter designs have been developed for cryogenic low-level measurements, driven by the growing interest in fundamental quantum-physical phenomena at energy scales corresponding to temperatures in the few millikelvin regime. However, a single filter concept is often insufficient to thermalize the electronic system to the cryogenic bath and eliminate spurious high frequency noise. Moreover, the available concepts often provide inadequate filtering to operate at temperatures below 10 mK, which are routinely available now in dilution cryogenic systems. Herein we provide a comprehensive analysis of commonly used filter types, introduce a novel compact filter type based on ferrite compounds optimized for the frequency range above 20 GHz, and develop an improved filtering scheme providing adaptable broad-band low-pass characteristic for cryogenic low-level and quantum measurement applications at temperatures down to few millikelvin.

  20. Modelling modulation perception : modulation low-pass filter or modulation filter bank?

    NARCIS (Netherlands)

    Dau, T.; Kollmeier, B.; Kohlrausch, A.G.

    1995-01-01

    In current models of modulation perception, the stimuli are first filtered and nonlinearly transformed (mostly half-wave rectified). In order to model the low-pass characteristic of measured modulation transfer functions, the next stage in the models is a first-order low-pass filter with a typical

  1. High frequency fishbone driven by passing energetic ions in tokamak plasmas

    Science.gov (United States)

    Wang, Feng; Yu, L. M.; Fu, G. Y.; Shen, Wei

    2017-05-01

    High frequency fishbone instability driven by passing energetic ions was first reported in the Princeton beta experiment with tangential neutral-beam-injection (Heidbrink et al 1986 Phys. Rev. Lett. 57 835-8). It could play an important role for ITER-like burning plasmas, where α particles are mostly passing particles. In this work, a generalized energetic ion distribution function and finite drift orbit width effect are considered to improve the theoretical model for passing particle driving fishbone instability. For purely passing energetic ions with zero drift orbit width, the kinetic energy δ {{W}k} is derived analytically. The derived analytic expression is more accurate as compared to the result of previous work (Wang 2001 Phys. Rev. Lett. 86 5286-8). For a generalized energetic ion distribution function, the fishbone dispersion relation is derived and is solved numerically. Numerical results show that broad and off-axis beam density profiles can significantly increase the beam ion beta threshold {βc} for instability and decrease mode frequency.

  2. Topical perfluorodecalin resolves immediate whitening reactions and allows rapid effective multiple pass treatment of tattoos.

    Science.gov (United States)

    Reddy, Kavitha K; Brauer, Jeremy A; Anolik, Robert; Bernstein, Leonard; Brightman, Lori; Hale, Elizabeth; Karen, Julie; Weiss, Elliot; Geronemus, Roy G

    2013-02-01

    Laser tattoo removal using multiple passes per session, with each pass delivered after spontaneous resolution of whitening, improves tattoo fading in a 60-minute treatment time. Our objective was to evaluate the safety and efficacy of topical perfluorodecalin (PFD) in facilitating rapid effective multiple-pass tattoo removal. In a randomized, controlled study using Q-switched ruby or Nd:YAG laser, 22 previously treated tattoos were treated with 3 passes using PFD to resolve whitening after each pass ("R0 method"). In previously untreated symmetric tattoos, seven were treated over half of the tattoo with the R20 method, and the opposite half with 4 passes using PFD (R0 method); two were treated over half with a single pass and the opposite half with 4 passes using PFD (R0 method); and six treated over half with a single pass followed by PFD and the opposite half with a single pass alone. Blinded dermatologists rated tattoo fading at 1-3 months. Optical coherence tomography (OCT) imaging of whitening was performed in two tattoos. Topical PFD clinically resolved immediate whitening reactions within a mean 5 seconds (range 3-10 seconds). Tattoos treated with the R0 method demonstrated excellent fading in an average total treatment time of 5 minutes. Tattoo areas treated with the R0 method demonstrated equal fading compared to the R20 method, and improved fading compared to a single pass method. OCT imaging of whitening demonstrated epidermal and dermal hyper-reflective "bubbles" that dissipated until absent at 9-10 minutes after PFD application, and at 20 minutes without intervention. Multiple-pass tattoo removal using PFD to deliver rapid sequential passes (R0 method) appears equally effective as the R20 method, in a total treatment time averaging 5 minutes, and more effective than single pass treatment. OCT-visualized whitening-associated "bubbles," upon treatment with PFD, resolve twice as rapidly as spontaneous resolution. Copyright © 2012 Wiley

  3. The Swedish Blood Pass project.

    Science.gov (United States)

    Berglund, B; Ekblom, B; Ekblom, E; Berglund, L; Kallner, A; Reinebo, P; Lindeberg, S

    2007-06-01

    Manipulation of the blood's oxygen carrying capacity (CaO(2)) through reinfusion of red blood cells, injections of recombinant erythropoietin or by other means results in an increased maximal oxygen uptake and concomitantly enhanced endurance performance. Therefore, there is a need to establish a system--"A Blood Pass"--through which such illegal and unethical methods can be detected. Venous blood samples were taken under standardized conditions from 47 male and female Swedish national and international elite endurance athletes four times during the athletic year of the individual sport (beginning and end of the preparation period and at the beginning and during peak performance in the competition period). In these samples, different hematological values were determined. ON(hes) and OFF(hre) values were calculated according to the formula of Gore et al. A questionnaire regarding training at altitude, alcohol use and other important factors for hematological status was answered by the athletes. There were some individual variations comparing hematological values obtained at different times of the athletic year or at the same time in the athletic year but in different years. However, the median values of all individual hematological, ON(hes) and OFF(hre), values taken at the beginning and the end of the preparation or at the beginning and the end of the competition period, respectively, as well as median values for the preparation and competition periods in the respective sport, were all within the 95% confidence limit (CI) of each comparison. It must be mentioned that there was no gender difference in this respect. This study shows that even if there are some individual variations in different hematological values between different sampling times in the athletic year, median values of important hematological factors are stable over time. It must be emphasized that for each blood sample, the 95% CI in each athlete will be increasingly narrower. The conclusion is that

  4. A swath across the great divide: Kelp forests across the Samalga Pass biogeographic break

    Science.gov (United States)

    Konar, Brenda H.; Edwards, Matthew S.; Bland, Aaron; Metzger, Jacob; Ravelo, Alexandra; Traiger, Sarah; Weitzman, Ben P.

    2017-01-01

    Biogeographic breaks are often described as locations where a large number of species reach their geographic range limits. Samalga Pass, in the eastern Aleutian Archipelago, is a known biogeographic break for the spatial distribution of several species of offshore-pelagic communities, including numerous species of cold-water corals, zooplankton, fish, marine mammals, and seabirds. However, it remains unclear whether Samalga Pass also serves as a biogeographic break for nearshore benthic communities. The occurrence of biogeographic breaks across multiple habitats has not often been described. In this study, we examined if the biogeographic break for offshore-pelagic communities applies to nearshore kelp forests. To examine whether Samalga Pass serves as a biogeographic break for kelp forest communities, this study compared abundance, biomass and percent bottom cover of species associated with kelp forests on either side of the pass. We observed marked differences in kelp forest community structure, with some species reaching their geographic range limits on the opposing sides of the pass. In particular, the habitat-forming kelp Nereocystis luetkeana, and the predatory sea stars Pycnopodia helianthoides and Orthasterias koehleri all occurred on the eastern side of Samalga Pass but were not observed west of the pass. In contrast, the sea star Leptasterias camtschatica dispar was observed only on the western side of the pass. We also observed differences in overall abundance and biomass of numerous associated fish, invertebrate and macroalgal species on opposing sides of the pass. We conclude that Samalga Pass is important biogeographic break for kelp forest communities in the Aleutian Archipelago and may demark the geographic range limits of several ecologically important species.

  5. Migratory Behavior and Survival of Juvenile Salmonids in the Lower Columbia River, Estuary, and Plume in 2010

    Energy Technology Data Exchange (ETDEWEB)

    McMichael, Geoffrey A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Harnish, Ryan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Skalski, John R. [Univ. of Washington, Seattle, WA (United States); Deters, Katherine A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ham, Kenneth D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Townsend, Richard L. [Univ. of Washington, Seattle, WA (United States); Titzler, P. Scott [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hughes, Michael S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kim, Jin A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Trott, Donna M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2011-09-01

    Uncertainty regarding the migratory behavior and survival of juvenile salmonids passing through the lower Columbia River and estuary after negotiating dams on the Federal Columbia River Power System (FCRPS) prompted the development and application of the Juvenile Salmon Acoustic Telemetry System (JSATS). The JSATS has been used to investigate the survival of juvenile salmonid smolts between Bonneville Dam (river kilometer (rkm) 236) and the mouth of the Columbia River annually since 2004. In 2010, a total of 12,214 juvenile salmonids were implanted with both a passive integrated transponder (PIT) and a JSATS acoustic transmitter. Using detection information from JSATS receiver arrays deployed on dams and in the river, estuary, and plume, the survival probability of yearling Chinook salmon and steelhead smolts tagged at John Day Dam was estimated form multiple reaches between rkm 153 and 8.3 during the spring. During summer, the survival probability of subyearling Chinook salmon was estimated for the same reaches. In addition, the influence of routes of passage (e.g., surface spill, deep spill, turbine, juvenile bypass system) through the lower three dams on the Columbia River (John Day, The Dalles, and Bonneville) on juvenile salmonid smolt survival probability from the dams to rkm 153 and then between rkm 153 and 8.3 was examined to increase understanding of the immediate and latent effects of dam passage on juvenile salmon survival. Similar to previous findings, survival probability was relatively high (>0.95) for most groups of juvenile salmonids from the Bonneville Dam tailrace to about rkm 50. Downstream of rkm 50 the survival probability of all species and run types we examined decreased markedly. Steelhead smolts suffered the highest mortality in this lower portion of the Columbia River estuary, with only an estimated 60% of the tagged fish surviving to the mouth of the river. In contrast, yearling and subyearling Chinook salmon smolts survived to the mouth

  6. Note-Taking and Secondary Students with Learning Disabilities: Challenges and Solutions

    Science.gov (United States)

    Boyle, Joseph R.

    2012-01-01

    As more secondary students with learning disabilities (LD) enroll in advanced content-area classes and are expected to pass state exams, they are faced with the challenge of mastering difficult concepts and abstract vocabulary while learning content. Once in these classes, students must learn from lectures that move at a quick pace, record…

  7. Complete hazard ranking to analyze right-censored data: An ALS survival study.

    Directory of Open Access Journals (Sweden)

    Zhengnan Huang

    2017-12-01

    Full Text Available Survival analysis represents an important outcome measure in clinical research and clinical trials; further, survival ranking may offer additional advantages in clinical trials. In this study, we developed GuanRank, a non-parametric ranking-based technique to transform patients' survival data into a linear space of hazard ranks. The transformation enables the utilization of machine learning base-learners including Gaussian process regression, Lasso, and random forest on survival data. The method was submitted to the DREAM Amyotrophic Lateral Sclerosis (ALS Stratification Challenge. Ranked first place, the model gave more accurate ranking predictions on the PRO-ACT ALS dataset in comparison to Cox proportional hazard model. By utilizing right-censored data in its training process, the method demonstrated its state-of-the-art predictive power in ALS survival ranking. Its feature selection identified multiple important factors, some of which conflicts with previous studies.

  8. The serial message-passing schedule for LDPC decoding algorithms

    Science.gov (United States)

    Liu, Mingshan; Liu, Shanshan; Zhou, Yuan; Jiang, Xue

    2015-12-01

    The conventional message-passing schedule for LDPC decoding algorithms is the so-called flooding schedule. It has the disadvantage that the updated messages cannot be used until next iteration, thus reducing the convergence speed . In this case, the Layered Decoding algorithm (LBP) based on serial message-passing schedule is proposed. In this paper the decoding principle of LBP algorithm is briefly introduced, and then proposed its two improved algorithms, the grouped serial decoding algorithm (Grouped LBP) and the semi-serial decoding algorithm .They can improve LBP algorithm's decoding speed while maintaining a good decoding performance.

  9. Interpretation of surface-water circulation, Aransas Pass, Texas, using Landsat imagery

    Science.gov (United States)

    Finley, R. J.; Baumgardner, R. W., Jr.

    1980-01-01

    The development of plumes of turbid surface water in the vicinity of Aransas Pass, Texas has been analyzed using Landsat imagery. The shape and extent of plumes present in the Gulf of Mexico is dependent on the wind regime and astronomical tide prior to and at the time of satellite overpass. The best developed plumes are evident when brisk northerly winds resuspend bay-bottom muds and flow through Aransas Pass is increased by wind stress. Seaward diversion of nearshore waters by the inlet jetties was also observed. A knowledge of surface-water circulation through Aransas Pass under various wind conditions is potentially valuable for monitoring suspended and surface pollutants

  10. Creep Deformation and Rupture Behavior of Single- and Dual-Pass 316LN Stainless-Steel-Activated TIG Weld Joints

    Science.gov (United States)

    Vijayanand, V. D.; Vasudevan, M.; Ganesan, V.; Parameswaran, P.; Laha, K.; Bhaduri, A. K.

    2016-06-01

    Creep deformation and rupture behavior of single-pass and dual-pass 316LN stainless steel (SS) weld joints fabricated by an autogenous activated tungsten inert gas welding process have been assessed by performing metallography, hardness, and conventional and impression creep tests. The fusion zone of the single-pass joint consisted of columnar zones adjacent to base metals with a central equiaxed zone, which have been modified extensively by the thermal cycle of the second pass in the dual-pass joint. The equiaxed zone in the single-pass joint, as well as in the second pass of the dual-pass joint, displayed the lowest hardness in the joints. In the dual-pass joint, the equiaxed zone of the first pass had hardness comparable to the columnar zone. The hardness variations in the joints influenced the creep deformation. The equiaxed and columnar zone in the first pass of the dual-pass joint was more creep resistant than that of the second pass. Both joints possessed lower creep rupture life than the base metal. However, the creep rupture life of the dual-pass joint was about twofolds more than that of the single-pass joint. Creep failure in the single-pass joint occurred in the central equiaxed fusion zone, whereas creep cavitation that originated in the second pass was blocked at the weld pass interface. The additional interface and strength variation between two passes in the dual-pass joint provides more restraint to creep deformation and crack propagation in the fusion zone, resulting in an increase in the creep rupture life of the dual-pass joint over the single-pass joint. Furthermore, the differences in content, morphology, and distribution of delta ferrite in the fusion zone of the joints favors more creep cavitation resistance in the dual-pass joint over the single-pass joint with the enhancement of creep rupture life.

  11. The Role of Leadership in Surviving a School Shooting

    Science.gov (United States)

    Brown, Carleton H.

    2018-01-01

    At a small rural middle school in the southern United States, two students murdered a teacher, four students, and injured 10 during a shooting spree. This case represents the lived experiences of a school principal, counselor, and community that survived the deadly rampage. The case highlights the challenges that school leaders may face such as…

  12. The force on an object passing through a magnetic fluid seal

    CERN Document Server

    Morton, G

    2002-01-01

    Forces on solid objects passed through a magnetic liquid plug in a tube are measured. A simple one-dimensional model is developed based on hydrostatic and magnetic pressures. The results demonstrate its potential to be used to separate two fluids while allowing solids to pass from one fluid to the other.

  13. Sand transport in a two pass internal cooling duct with rib turbulators

    International Nuclear Information System (INIS)

    Singh, Sukhjinder; Tafti, Danesh; Reagle, Colin; Delimont, Jacob; Ng, Wing; Ekkad, Srinath

    2014-01-01

    Highlights: • Highest particle impingement observed in the bend and first quarter of 2nd pass. • Average particle impingement per pitch is 28% higher in the second pass. • Rib faces are by far the most susceptible to particle impingement. • Particle impingement is sensitive to particle size. • Particle impingement is sensitive to wall collision model used. - Abstract: Jet engines often operate under dirty conditions where large amounts of particulate matter can be ingested, especially, sand, ash and dirt. Particulate matter in different engine components can lead to degradation in performance. The focus of this study is to investigate the sand transport and deposition in the internal cooling passages of turbine blades. A two pass stationary square duct with rib turbulators subjected to sand ingestion is studied using Large Eddy Simulations (LES). Each pass has ribs on two opposite walls and aligned normal to the main flow direction. The rib pitch to rib height (P/e) is 9.28, the rib height to channel hydraulic diameter (e/D h ) is 0.0625 and calculations have been carried out for a bulk Reynolds number of 25,000. Particle sizes in the range 0.5–25 μm are considered, with the same size distribution as found in Arizona Road Dust (medium). Large Eddy Simulation (LES) with a wall-model is used to model the flow and sand particles are modeled using a discrete Lagrangian framework. Results quantify the distribution of particle impingement density on all surfaces. Highest particle impingement density is found in the first quarter section of the second pass after the 180° turn, where the recorded impingement is more than twice that of any other region. It is also found that the average particle impingement per pitch is 28% higher in the second pass than the first pass. Results show lower particle tendency to impact the region immediately behind the rib in the first pass compared to the second pass where particle impingement is more uniform in the region

  14. Nerve Growth Factor in Cancer Cell Death and Survival

    International Nuclear Information System (INIS)

    Molloy, Niamh H.; Read, Danielle E.; Gorman, Adrienne M.

    2011-01-01

    One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we review the growing literature which shows that neurotrophins contribute to pro-survival signaling in many different types of cancer. In particular, nerve growth factor, the archetypal neurotrophin, has been shown to play a role in tumorigenesis over the past decade. Nerve growth factor mediates its effects through its two cognate receptors, TrkA, a receptor tyrosine kinase and p75 NTR , a member of the death receptor superfamily. Depending on the tumor origin, pro-survival signaling can be mediated by TrkA receptors or by p75 NTR . For example, in breast cancer the aberrant expression of nerve growth factor stimulates proliferative signaling through TrkA and pro-survival signaling through p75 NTR . This latter signaling through p75 NTR promotes increased resistance to the induction of cell death by chemotherapeutic treatments. In contrast, in prostate cells the p75 NTR mediates cell death and prevents metastasis. In prostate cancer, expression of this receptor is lost, which contributes to tumor progression by allowing cells to survive, proliferate and metastasize. This review focuses on our current knowledge of neurotrophin signaling in cancer, with a particular emphasis on nerve growth factor regulation of cell death and survival in cancer

  15. Robust detection of heart beats in multimodal records using slope- and peak-sensitive band-pass filters.

    Science.gov (United States)

    Pangerc, Urška; Jager, Franc

    2015-08-01

    In this work, we present the development, architecture and evaluation of a new and robust heart beat detector in multimodal records. The detector uses electrocardiogram (ECG) signals, and/or pulsatile (P) signals, such as: blood pressure, artery blood pressure and pulmonary artery pressure, if present. The base approach behind the architecture of the detector is collecting signal energy (differentiating and low-pass filtering, squaring, integrating). To calculate the detection and noise functions, simple and fast slope- and peak-sensitive band-pass digital filters were designed. By using morphological smoothing, the detection functions were further improved and noise intervals were estimated. The detector looks for possible pacemaker heart rate patterns and repairs the ECG signals and detection functions. Heart beats are detected in each of the ECG and P signals in two steps: a repetitive learning phase and a follow-up detecting phase. The detected heart beat positions from the ECG signals are merged into a single stream of detected ECG heart beat positions. The merged ECG heart beat positions and detected heart beat positions from the P signals are verified for their regularity regarding the expected heart rate. The detected heart beat positions of a P signal with the best match to the merged ECG heart beat positions are selected for mapping into the noise and no-signal intervals of the record. The overall evaluation scores in terms of average sensitivity and positive predictive values obtained on databases that are freely available on the Physionet website were as follows: the MIT-BIH Arrhythmia database (99.91%), the MGH/MF Waveform database (95.14%), the augmented training set of the follow-up phase of the PhysioNet/Computing in Cardiology Challenge 2014 (97.67%), and the Challenge test set (93.64%).

  16. Energy analysis and improvement potential of finned double-pass solar collector

    International Nuclear Information System (INIS)

    Fudholi, Ahmad; Sopian, Kamaruzzaman; Othman, Mohd Yusof; Ruslan, Mohd Hafidz; Bakhtyar, B.

    2013-01-01

    Highlights: • The developed steady state model predicting the thermal performance of double-pass solar collectors is presented. • The main objective of this paper is to analyze the energy and exergy of finned double-pass solar collector. • A new mathematical model, solution procedure, and test results are presented. • The thermal performances and improvement potential of the double-pass solar collectors are discussed. - Abstract: Steady state energy balance equations for the finned double-pass solar collector have been developed. These equations were solved using the matrix inversion method. The predicted results were in agreement with the results obtained from the experiments. The predictions and experiments were observed at the mass flow rate ranging between 0.03 kg/s and 0.1 kg/s, and solar radiation ranging between 400 W/m 2 and 800 W/m 2 . The effects of mass flow rates and solar radiation levels on energy efficiency, exergy efficiency and the improvement potential have been observed. The optimum energy efficiency is approximately 77%, which was observed at the mass flow rate of 0.09 kg/s. The optical efficiency of the finned double-pass solar collector is approximately 70–80%. The exergy efficiency is approximately 15–28% and improvement potential of 740–1070 W for a solar radiation of 425–790 W/m 2

  17. Low-pass sequencing for microbial comparative genomics

    Directory of Open Access Journals (Sweden)

    Kennedy Sean

    2004-01-01

    Full Text Available Abstract Background We studied four extremely halophilic archaea by low-pass shotgun sequencing: (1 the metabolically versatile Haloarcula marismortui; (2 the non-pigmented Natrialba asiatica; (3 the psychrophile Halorubrum lacusprofundi and (4 the Dead Sea isolate Halobaculum gomorrense. Approximately one thousand single pass genomic sequences per genome were obtained. The data were analyzed by comparative genomic analyses using the completed Halobacterium sp. NRC-1 genome as a reference. Low-pass shotgun sequencing is a simple, inexpensive, and rapid approach that can readily be performed on any cultured microbe. Results As expected, the four archaeal halophiles analyzed exhibit both bacterial and eukaryotic characteristics as well as uniquely archaeal traits. All five halophiles exhibit greater than sixty percent GC content and low isoelectric points (pI for their predicted proteins. Multiple insertion sequence (IS elements, often involved in genome rearrangements, were identified in H. lacusprofundi and H. marismortui. The core biological functions that govern cellular and genetic mechanisms of H. sp. NRC-1 appear to be conserved in these four other halophiles. Multiple TATA box binding protein (TBP and transcription factor IIB (TFB homologs were identified from most of the four shotgunned halophiles. The reconstructed molecular tree of all five halophiles shows a large divergence between these species, but with the closest relationship being between H. sp. NRC-1 and H. lacusprofundi. Conclusion Despite the diverse habitats of these species, all five halophiles share (1 high GC content and (2 low protein isoelectric points, which are characteristics associated with environmental exposure to UV radiation and hypersalinity, respectively. Identification of multiple IS elements in the genome of H. lacusprofundi and H. marismortui suggest that genome structure and dynamic genome reorganization might be similar to that previously observed in the

  18. Quality of life of cancer patients - definition, stages of survival and factors of influence

    International Nuclear Information System (INIS)

    Yaneva, M.

    2005-01-01

    The aim of the review is to represent the state of assessment of quality of life of cancer patients in the investigation of different authors. It is important to know the basic ideas of quality of life during the complex treatment of cancer patients, in order to choose such methods that will lead to an improvement of their living. The definition of the concept 'quality of life', the stages that patients pass and the influencing factors should be familiar to the therapists. Today patients live longer after a complex treatment - it is important how and what challenges they are facing together with their relatives and the medical staff. The attempts to define and measure the quality of life of cancer patients date from the last ten years. This is a social demand to get such medical care, which should be at a certain level leading not only to a longer survival but this life to be of a higher quality. The patients' perceptions and preferences concerning quality of life must be given greater emphasis in cancer treatment decision making which will better his state after a competent explanation of therapists. A quality of life of every patient is as an individual problem as a part of the social health. A classification of the problem of quality of life will enlarge the oncological therapeutic concept

  19. [Immunogenicity and protective efficacy of pertactin recombinants against Bordetella bronchiseptica challenge].

    Science.gov (United States)

    Zhao, Zhanqin; Wang, Chen; Xue, Yun; Ding, Ke; Zhang, Chunjie; Cheng, Xiangchao; Li, Yinju; Liu, Yichen; Wu, Tingcai

    2010-09-01

    In this study we showed the immunogenicity and protective efficacy of five pertactin recombinants against Bordetella bronchiseptica (Bb) challenge. The complete coding sequence (2040 bp) of the prn gene (PRN) and its fragments,5'-terminal 1173 bp fragment (PN),3'-terminal 867 bp fragment (PC), two copies of region I (654 bp; PR I) in PN, and 2 copies of region II (678 bp; PR II) in PC, were separately cloned into the prokaryotic expression vector pGEX-KG, and expressed in the Eschierichia coli BL21 (DE3) using induction by isopropyl-beta-D-thiogalactopyranoside. The recombinant proteins were named GST-PRN, GST-PN, GST-PC, GST-2PR I and GST-2PR II. All five recombinant proteins showed immunological reactivity in the Western-blot analysis. Mice, immunized subcutaneously with two doses of the purified proteins mixed with an equal volume of Freund's adjuvant,produced robust PRN-specific IgG antibody levels. When challenged, 6 of 9 mice in GST-2PR I group and all 9 mice in the other groups survived intranasal challenge with three times the 50% lethal dose (LD50) of virulent Bb HH0809. After challenge with 10 LD50 7/9,3/9,6/9,1/10 and 6/10 of the mice survived. Furthermore, complete protection against intraperitoneal (i.p.) challenge with 10 LD50 of HH0809 was observed in mice that were injected i.p. with 0.5 ml rabbit anti-GST-PRN, GST-PN,GST-PC or GST-2PR II serum. Only 1 of 10 mice survived in the group of mice that received anti-GST-2PR I, and no survivors were noted in the group of mice that received PRN-absorbed rabbit antiserum (0/5). In this study,we showed that all of five pertactin recombinants had differential immunogenicity and protective efficacy against Bb challenge. Mice immunized with GST-PC had better survival against fatal Bb challenge than did those immunized with GST-PN. In addition, GST-2PR II and GST-2PR I provided the similar results These data may have implications for the development of safe and efficacious subunit vaccines for the prevention of

  20. A novel square-root domain realization of first order all-pass filter

    OpenAIRE

    ÖLMEZ, Sinem; ÇAM, Uğur

    2010-01-01

    In this paper, a new square-root domain, first order, all-pass filter based on the MOSFET square law is presented. The proposed filter is designed by using nonlinear mapping on the state variables of a state space description of the transfer function. To the best knowledge of the authors, the filter is the first square-root domain first order all-pass structure designed by using state space synthesis method in the literature. The center frequency of the all-pass filter is not only a...

  1. Standardized Testing Practices: Effect on Graduation and NCLEX® Pass Rates.

    Science.gov (United States)

    Randolph, Pamela K

    The use standardized testing in pre-licensure nursing programs has been accompanied by conflicting reports of effective practices. The purpose of this project was to describe standardized testing practices in one states' nursing programs and discover if the use of a cut score or oversight of remediation had any effect on (a) first time NCLEX® pass rates, (b) on-time graduation (OTG) or (c) the combination of (a) and (b). Administrators of 38 nursing programs in one Southwest state were sent surveys; surveys were returned by 34 programs (89%). Survey responses were compared to each program's NCLEX pass rate and on-time graduation rate; t-tests were conducted for significant differences associated with a required minimum score (cut score) and oversight of remediation. There were no significant differences in NCLEX pass or on-time graduation rates related to establishment of a cut score. There was a significant difference when the NCLEX pass rate and on-time graduation rate were combined (Outcome Index "OI") with significantly higher program outcomes (P=.02.) for programs without cut-scores. There were no differences associated with faculty oversight of remediation. The results of this study do not support establishment of a cut-score when implementing a standardized testing. Copyright © 2016. Published by Elsevier Inc.

  2. Fuel-element failures in Hanford single-pass reactors 1944--1971

    Energy Technology Data Exchange (ETDEWEB)

    Gydesen, S.P.

    1993-07-01

    The primary objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation dose that individuals could have received as a result of emissions since 1944 from the US Department of Energy`s (DOE) Hanford Site near Richland, Washington. To estimate the doses, the staff of the Source Terms Task use operating information from historical documents to approximate the radioactive emissions. One source of radioactive emissions to the Columbia River came from leaks in the aluminum cladding of the uranium metal fuel elements in single-pass reactors. The purpose of this letter report is to provide photocopies of the documents that recorded these failures. The data from these documents will be used by the Source Terms Task to determine the contribution of single-pass reactor fuel-element failures to the radioactivity of the reactor effluent from 1944 through 1971. Each referenced fuel-element failure occurring in the Hanford single-pass reactors is addressed. The first recorded failure was in 1948, the last in 1970. No records of fuel-element failures were found in documents prior to 1948. Data on the approximately 2000 failures which occurred during the 28 years (1944--1971) of Hanford single-pass reactor operations are provided in this report.

  3. Breast cancer data analysis for survivability studies and prediction.

    Science.gov (United States)

    Shukla, Nagesh; Hagenbuchner, Markus; Win, Khin Than; Yang, Jack

    2018-03-01

    Breast cancer is the most common cancer affecting females worldwide. Breast cancer survivability prediction is challenging and a complex research task. Existing approaches engage statistical methods or supervised machine learning to assess/predict the survival prospects of patients. The main objectives of this paper is to develop a robust data analytical model which can assist in (i) a better understanding of breast cancer survivability in presence of missing data, (ii) providing better insights into factors associated with patient survivability, and (iii) establishing cohorts of patients that share similar properties. Unsupervised data mining methods viz. the self-organising map (SOM) and density-based spatial clustering of applications with noise (DBSCAN) is used to create patient cohort clusters. These clusters, with associated patterns, were used to train multilayer perceptron (MLP) model for improved patient survivability analysis. A large dataset available from SEER program is used in this study to identify patterns associated with the survivability of breast cancer patients. Information gain was computed for the purpose of variable selection. All of these methods are data-driven and require little (if any) input from users or experts. SOM consolidated patients into cohorts of patients with similar properties. From this, DBSCAN identified and extracted nine cohorts (clusters). It is found that patients in each of the nine clusters have different survivability time. The separation of patients into clusters improved the overall survival prediction accuracy based on MLP and revealed intricate conditions that affect the accuracy of a prediction. A new, entirely data driven approach based on unsupervised learning methods improves understanding and helps identify patterns associated with the survivability of patient. The results of the analysis can be used to segment the historical patient data into clusters or subsets, which share common variable values and

  4. Challenges of the 21st Century Ghanaian Universities | Braimah ...

    African Journals Online (AJOL)

    After going through a period of higher educational reforms, Ghanaian public Universities are now being challenged to determine their future survival. ... Information and Communication Technology, Changing Student Mix, Quality Enhancement ...

  5. Soil Moisture Active and Passive (SMAP) White-Painted Expanded Polystyrene (EPS) Radome Survivability Test

    Science.gov (United States)

    Mikhaylov, Rebecca; Kwack, Eug; Stegman, Matthew; Dawson, Douglas; Hoffman, Pamela

    2015-01-01

    NASA's SMAP Mission launched in January 2015 into a 685 km near-polar, sun-synchronous orbit. The SMAP instrument architecture incorporates an L-band radar and radiometer which share a common feedhorn and mesh reflector. The instrument rotates about the nadir axis at approximately 15 rpm, thereby providing a conically scanning wide swath antenna beam that is capable of achieving global coverage within three days. The radiometer and its associated electronics have tight thermal stability requirements in order to meet the required surface emittance measurement precision from space. Maintaining the thermal stabilities is quite challenging because the radiometer is located on a spinning platform that can either be in full sunlight or eclipse, and thus exposed to a highly transient environment. Stability requirements were met by integrating a light-weight Expanded Polystyrene (EPS) radome into the design to prevent solar illumination of the feed horn interior. The radome was painted white since the thermo-optical properties of bare sunlit EPS degrade rapidly over the three-year mission. Milling of the EPS and solvent within the white paint created cavities on the EPS surface which may introduce localized hot spots possibly violating the EPS glass transition temperature of 96degC and leading to structural integrity concerns. A three-day thermal test was conducted in a vacuum chamber to verify survivability of the radome during a simulated non-spin fault condition at end of mission. A portable solar simulator illuminated the test article and the beam irradiance was kept nearly constant during the entire 50 hour test, except during the first hour which simulated the expected 79degC on-orbit surface temperature of the radome. The test article survived based on the established pass criteria for three separate metrics: dimensional, optical property, and color. If any hot spots exist locally, they did not cause any observable permanent deformation when compared to pre- and

  6. Number of Migration Scenarios Passing through each HUC

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forest dwelling neotropical migratory birds require intact forested stopovers during migration. The number of paths that pass through a HUC highlight that huc's...

  7. Affordances shape pass kick behavior in association football : effects of distance and social context

    NARCIS (Netherlands)

    Pepping, Gert-Jan; Heijmerikx, Johan; de Poel, Harjo J.

    2011-01-01

    A prerequisite for accurate passing in association football is that a player perceives the affordances, that is, the opportunities for action, of a given situation. The present study examined how affordances shape passing in association football by comparing the performance of pass-kicks in two task

  8. A novel SFG structure for C-T high-pass filters

    OpenAIRE

    Nielsen, Ivan Riis

    1993-01-01

    A signal flow graph (SFG) structure for simulating passive high-pass ladder filters, called the incremental integration structure, is proposed. The structure requires the use of integrators with nonintegrating inputs, and an implementation based on the MOSFET-C technique is discussed. The incremental integration structure is compared to the leapfrog and direct SFG simulation structures. Leapfrog high-pass filters are relatively simple and show good noise properties, but they are based on diff...

  9. The Procalcitonin And Survival Study (PASS) – A Randomised multi-center investigator-initiated trial to investigate whether daily measurements biomarker Procalcitonin and pro-active diagnostic and therapeutic responses to abnormal Procalcitonin levels, can improve survival in intensive care unit patients. Calculated sample size (target population): 1000 patients

    Science.gov (United States)

    Jensen, Jens-Ulrik; Lundgren, Bettina; Hein, Lars; Mohr, Thomas; Petersen, Pernille L; Andersen, Lasse H; Lauritsen, Anne Ø; Hougaard, Sine; Mantoni, Teit; Bømler, Bonnie; Thornberg, Klaus J; Thormar, Katrin; Løken, Jesper; Steensen, Morten; Carl, Peder; Petersen, J Asger; Tousi, Hamid; Søe-Jensen, Peter; Bestle, Morten; Hestad, Søren; Andersen, Mads H; Fjeldborg, Paul; Larsen, Kim M; Rossau, Charlotte; Thomsen, Carsten B; Østergaard, Christian; Kjær, Jesper; Grarup, Jesper; Lundgren, Jens D

    2008-01-01

    Background Sepsis and complications to sepsis are major causes of mortality in critically ill patients. Rapid treatment of sepsis is of crucial importance for survival of patients. The infectious status of the critically ill patient is often difficult to assess because symptoms cannot be expressed and signs may present atypically. The established biological markers of inflammation (leucocytes, C-reactive protein) may often be influenced by other parameters than infection, and may be unacceptably slowly released after progression of an infection. At the same time, lack of a relevant antimicrobial therapy in an early course of infection may be fatal for the patient. Specific and rapid markers of bacterial infection have been sought for use in these patients. Methods Multi-centre randomized controlled interventional trial. Powered for superiority and non-inferiority on all measured end points. Complies with, "Good Clinical Practice" (ICH-GCP Guideline (CPMP/ICH/135/95, Directive 2001/20/EC)). Inclusion: 1) Age ≥ 18 years of age, 2) Admitted to the participating intensive care units, 3) Signed written informed consent. Exclusion: 1) Known hyper-bilirubinaemia. or hypertriglyceridaemia, 2) Likely that safety is compromised by blood sampling, 3) Pregnant or breast feeding. Computerized Randomisation: Two arms (1:1), n = 500 per arm: Arm 1: standard of care. Arm 2: standard of care and Procalcitonin guided diagnostics and treatment of infection. Primary Trial Objective: To address whether daily Procalcitonin measurements and immediate diagnostic and therapeutic response on day-to-day changes in procalcitonin can reduce the mortality of critically ill patients. Discussion For the first time ever, a mortality-endpoint, large scale randomized controlled trial with a biomarker-guided strategy compared to the best standard of care, is conducted in an Intensive care setting. Results will, with a high statistical power answer the question: Can the survival of critically ill

  10. The Procalcitonin And Survival Study (PASS – A Randomised multi-center investigator-initiated trial to investigate whether daily measurements biomarker Procalcitonin and pro-active diagnostic and therapeutic responses to abnormal Procalcitonin levels, can improve survival in intensive care unit patients. Calculated sample size (target population: 1000 patients

    Directory of Open Access Journals (Sweden)

    Fjeldborg Paul

    2008-07-01

    Full Text Available Abstract Background Sepsis and complications to sepsis are major causes of mortality in critically ill patients. Rapid treatment of sepsis is of crucial importance for survival of patients. The infectious status of the critically ill patient is often difficult to assess because symptoms cannot be expressed and signs may present atypically. The established biological markers of inflammation (leucocytes, C-reactive protein may often be influenced by other parameters than infection, and may be unacceptably slowly released after progression of an infection. At the same time, lack of a relevant antimicrobial therapy in an early course of infection may be fatal for the patient. Specific and rapid markers of bacterial infection have been sought for use in these patients. Methods Multi-centre randomized controlled interventional trial. Powered for superiority and non-inferiority on all measured end points. Complies with, "Good Clinical Practice" (ICH-GCP Guideline (CPMP/ICH/135/95, Directive 2001/20/EC. Inclusion: 1 Age ≥ 18 years of age, 2 Admitted to the participating intensive care units, 3 Signed written informed consent. Exclusion: 1 Known hyper-bilirubinaemia. or hypertriglyceridaemia, 2 Likely that safety is compromised by blood sampling, 3 Pregnant or breast feeding. Computerized Randomisation: Two arms (1:1, n = 500 per arm: Arm 1: standard of care. Arm 2: standard of care and Procalcitonin guided diagnostics and treatment of infection. Primary Trial Objective: To address whether daily Procalcitonin measurements and immediate diagnostic and therapeutic response on day-to-day changes in procalcitonin can reduce the mortality of critically ill patients. Discussion For the first time ever, a mortality-endpoint, large scale randomized controlled trial with a biomarker-guided strategy compared to the best standard of care, is conducted in an Intensive care setting. Results will, with a high statistical power answer the question: Can the survival

  11. CT-guided core biopsy of malignant lung lesions: how many needle passes are needed?

    International Nuclear Information System (INIS)

    Lim, Chaehun; Han, Dae Hee; Lee, Kyo Young; Kim, Young Kyoon; Ko, Jeong Min

    2013-01-01

    The study aims to determine the number of needle pass in the CT-guided core needle biopsy (CNB) in making a diagnosis of pulmonary malignancy. A total of 434 CNB records were retrospectively reviewed. The specimen obtained from each needle pass was put in a formalin container and then labelled for separate histopathological reporting. The patients were divided into five groups according to the total number of needle passes (n=1, n=2, n=3, n=4 and n≥5). In each of the groups 2–4, it was analysed how many needle passes are required before a plateau in diagnostic yield is achieved. CNB produced 283 true-positive and 23 false-negative diagnosis of malignancy. Cumulative sensitivity significantly (P<0.05) increased between the first and second as well as the second and the third (if done) needle passes, but not between the third and fourth ones. Three coaxial needle passes might be optimal in the diagnosis of lung malignancy.

  12. Passing excellence

    Science.gov (United States)

    Tsoupikova, Daria

    2007-02-01

    This paper describes the research and development of a virtual reality visualization project "Passing excellence" about the world famous architectural ensemble "Kizhi". The Kizhi Pogost is located on an island in Lake Onega in northern Karelia in Russia. It is an authentic museum of an ancient wood building tradition which presents a unique artistic achievement. This ensemble preserves a concentration of masterpieces of the Russian heritage and is included in the List of Most Endangered Sites of the World Monuments Watch protected by World Heritage List of UNESCO. The project strives to create a unique virtual observation of the dynamics of the architectural changes of the museum area beginning from the 15th Century up to the 21st Century. The visualization is being created to restore the original architecture of Kizhi island based on the detailed photographs, architectural and geometric measurements, textural data, video surveys and resources from the Kizhi State Open-Air Museum archives. The project is being developed using Electro, an application development environment for the tiled display high-resolution graphics visualization system and can be shown on the virtual reality systems such as the GeoWall TM and the C-Wall.

  13. Parallel imaging for first-pass myocardial perfusion

    NARCIS (Netherlands)

    Irwan, Roy; Lubbers, Daniel D.; van der Vleuten, Pieter A.; Kappert, Peter; Gotte, Marco J. W.; Sijens, Paul E.

    Two parallel imaging methods used for first-pass myocardial perfusion imaging were compared in terms of signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and image artifacts. One used adaptive Time-adaptive SENSitivity Encoding (TSENSE) and the other used GeneRalized Autocalibrating

  14. An outlook on comparison of hybrid welds of different root pass and ...

    Indian Academy of Sciences (India)

    Pritesh Prajapati

    2018-05-11

    May 11, 2018 ... pass and filler pass of flux cored arc welding and gas metal arc welding were acquired. The comparative ... [2], GMAW-plasma welding [3], laser welding-gas tung- sten arc welding ..... by optical emission spectroscopy. Plasma ...

  15. Poly-β-hydroxybutyrate (PHB) accumulating Bacillus spp. improve the survival, growth and robustness of Penaeus monodon (Fabricius, 1798) postlarvae.

    Science.gov (United States)

    Laranja, Joseph Leopoldo Q; Ludevese-Pascual, Gladys L; Amar, Edgar C; Sorgeloos, Patrick; Bossier, Peter; De Schryver, Peter

    2014-10-10

    Low larval survival resulting from suboptimal culture conditions and luminous vibriosis poses a major problem for the larviculture of penaeid shrimp. In this study, a poly-β-hydroxybutyrate (PHB) accumulating mixed bacterial culture (mBC; 48.5% PHB on cell dry weight) and two PHB accumulating bacterial isolates, Bacillus sp. JL47 (54.7% PHB on cell dry weight) and Bacillus sp. JL1 (45.5% PHB on cell dry weight), were obtained from a Philippine shrimp culture pond and investigated for their capacity to improve growth, survival and robustness of Penaeus monodon postlarvae (PL). Shrimp PL1 and shrimp PL30 were provided with the PHB containing bacterial cultures in the feed for 30 days followed by, respectively, a challenge with pathogenic Vibrio campbellii and exposure to a lethal dose of ammonia. Prior to the pathogenic challenge or ammonia stress, growth and survival were higher for shrimp receiving the PHB accumulating bacteria as compared to shrimp receiving diets without bacterial additions. After exposure to the pathogenic challenge the shrimp fed PHB accumulating bacteria showed a higher survival as compared to non-treated shrimp, suggesting an increase in robustness for the shrimp. Similar effects were observed when shrimp PL30 were provided with the PHB accumulating bacterial cultures during a challenge with pathogenic V. campbellii through the water. The survival of shrimp exposed to lethal ammonia stress showed no significant difference between PHB accumulating bacteria-fed shrimp and non-PHB treated shrimp. The data illustrate that bacilli capable of accumulating PHB can provide beneficial effects to P. monodon post-larvae during culture in terms of growth performance, survival and resistance against pathogenic infection and ammonia stress. Further investigations are required to verify the PHB effect of the bacterial cultures on the shrimp. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Economic consequences of extra by-passes in district heating networks. Investment-, running- and maintenance costs

    International Nuclear Information System (INIS)

    Herbert, P.

    1995-02-01

    For various reasons, extra by-passes are installed in district heating networks to ensure a high flow temperature when the water circulation is insufficient. By 'extra by-pass' we here mean a connection between the distribution pipe and the return pipe. This study mainly deals with extra by-passes to prevent freezing. The estimation of the extra by-pass costs is based on the district heating rates. Our assumption is that an extra by-pass can be regarded as a substation in the district heating network, with regard to the demand for the water flow, heat and power. The reason is the difficulty to obtain available facts to estimate the real costs concerning extra by-passes. Therefore, the method can not claim that the information about the costs is exact but gives an indication of the size of them. The valves in an extra by-pass can be set more or less open. We assume that manual valves in extra by-passes are wide open. Thermostatic valves are, however, assumed to be adjusted in order to cause a very small water flow. 2 refs, 16 figs, 9 tabs, 6 appendices

  17. IMPACT OF THE REPEATED TRACTOR PASSES ON SOME PHYSICAL PROPERTIES OF SILTY LOAM SOIL

    Directory of Open Access Journals (Sweden)

    Dubravko Filipović

    2011-12-01

    Full Text Available The aim of this paper was to quantify soil compaction induced by tractor traffic on untilled wet silty loam soil (Mollic Fluvisol. Changes in penetration resistance, bulk density and total porosity were measured for detecting the soil compaction. Treatments include ten passes of a four-wheel drive tractor with the engine power of 54.0 kW and weight of 3560 kg (1580 kg on the front axle and 1980 kg on the rear axle, 2.41 m distance between axles. The tyres on the tractor were cross-ply, front 11.2-24 and rear 16.9-30, with the inflation pressure of 160 kPa and 100 kPa, respectively. The speed of tractor during passes over experimental plots was 5.0 km h-1. In comparison to control, each tractor pass induced an increase in soil penetration resistance at all depths, and the average increment ratios, determined as the average of all layers, were 9.8, 18.5 and 26.1% after one, five and ten passes, respectively. The bulk density also increased with number of tractor passes, but with less percentage increasing. The increment ratios comparison to the control were 3.6, 9.5 and 12.9% after one, five and ten passes, respectively. The total porosity decreased with the number of passes, and the decrement ratios were 4.5, 16.5 and 20.8% after one, five and ten passes, respectively.

  18. Theoretic derivation of directed acyclic subgraph algorithm and comparisons with message passing algorithm

    Science.gov (United States)

    Ha, Jeongmok; Jeong, Hong

    2016-07-01

    This study investigates the directed acyclic subgraph (DAS) algorithm, which is used to solve discrete labeling problems much more rapidly than other Markov-random-field-based inference methods but at a competitive accuracy. However, the mechanism by which the DAS algorithm simultaneously achieves competitive accuracy and fast execution speed, has not been elucidated by a theoretical derivation. We analyze the DAS algorithm by comparing it with a message passing algorithm. Graphical models, inference methods, and energy-minimization frameworks are compared between DAS and message passing algorithms. Moreover, the performances of DAS and other message passing methods [sum-product belief propagation (BP), max-product BP, and tree-reweighted message passing] are experimentally compared.

  19. Effect of probiotic supplemented diet on marine shrimp survival after challenge with Vibrio harveyi Efeito do uso de dieta suplementada com o probiótico sobre a sobrevivência de camarões marinhos após o desafio com Vibrio harveyi

    OpenAIRE

    F.N. Vieira; C.C. Buglione; J.P.L. Mouriño; A. Jatobá; M.L. Martins; D.D. Schleder; E.R. Andreatta; M.A. Barraco; L.A. Vinatea

    2010-01-01

    The effect of a Lactobacillus plantarum-supplemented diet on shrimp growth, digestive tract bacterial microbiota, survival, and some hemato-immunological parameters after an experimental challenge with Vibrio harveyi was studied. No difference (P>0.05) was observed in shrimp survival (80±6%) and final weight (6.63±0.56g) after 60 days feeding trial. Total bacteria count and Vibrio spp. count in the digestive tract were not diferent (P>0.05) until day 40, but they were lower (P0.05) than the c...

  20. Battle of Kasserine Pass: Defeat is a Matter of Scale

    Science.gov (United States)

    2016-05-26

    a ga inst Germany in World War II ; some historians even go so far as to anticipate defeat in the first battles of all major Ameri can wars. Martin ...the battle of Kasserine Pass prove the conventional wisdom that America is doomed to defeat in its first battles? Martin Blumenson, a prominent...Much study of the battle of Kasserine Pass has been done since Martin Blumenson wrote the original history in 1966. The ULTRA and MAGIC intercepts

  1. Transient analysis of the double pass photovoltaic thermal solar collector

    International Nuclear Information System (INIS)

    Alfegi, Ebrahim M.; Sopian, Kamaruzzaman; Abakr, Yousif A.

    2006-01-01

    A mathematical model of a double pass photovoltaic thermal (PV/T) solar collector is reported in this work. It is composed of five couple unsteady nonlinear partial differential equations which are solved by using Gear implicit numerical scheme. That model was validated against experimental data and was found to accurately predict the temperature of the circulated air as well as the temperature distribution of every static elements in a two-pass PV/T solar collector.(Author)

  2. Somalia: supporting the child survival agenda when routine health service is broken.

    Science.gov (United States)

    Mirza, Imran Raza; Kamadjeu, Raoul; Assegid, Kebede; Mulugeta, Abraham

    2012-03-01

    Somalia, one of the most unstable countries in the world, has been without a permanent government for nearly 2 decades. With a health system in total disarray, coverage of basic health interventions remains low and, maternal and child mortality is among the highest in the world. Health partners jointly outlined an integrated package of critical child survival interventions to be delivered through a population-based delivery strategy known as Child Health Days (CHDs), to reduce child mortality. Using this strategy, key child survival interventions are delivered to the community with an objective of reaching children Somalia every 6 months. Through this strategy, immunization services were reached in remote areas, and coverage disparity between the urban and rural areas was reduced from 17% (42% urban and 25% rural) to 10% (50% urban and 60% rural). In addition, infants were reached with a third dose of diphtheria-pertussis-tetanus vaccine, achieving 51% coverage during 2009 and 66% in 2010. This paper summarizes the challenges of scaling up child interventions in the troubled context of Somalia by reviewing the planning, implementation, and achievements of CHDs as well as reflecting on challenges for the future of child survival in Somalia.

  3. Wavenumber-domain separation of rail contribution to pass-by noise

    Science.gov (United States)

    Zea, Elias; Manzari, Luca; Squicciarini, Giacomo; Feng, Leping; Thompson, David; Arteaga, Ines Lopez

    2017-11-01

    In order to counteract the problem of railway noise and its environmental impact, passing trains in Europe must be tested in accordance to a noise legislation that demands the quantification of the noise generated by the vehicle alone. However, for frequencies between about 500 Hz and 1600 Hz, it has been found that a significant part of the measured noise is generated by the rail, which behaves like a distributed source and radiates plane waves as a result of the contact with the train's wheels. Thus the need arises for separating the rail contribution to the pass-by noise in that particular frequency range. To this end, the present paper introduces a wavenumber-domain filtering technique, referred to as wave signature extraction, which requires a line microphone array parallel to the rail, and two accelerometers on the rail in the vertical and lateral direction. The novel contributions of this research are: (i) the introduction and application of wavenumber (or plane-wave) filters to pass-by data measured with a microphone array located in the near-field of the rail, and (ii) the design of such filters without prior information of the structural properties of the rail. The latter is achieved by recording the array pressure, as well as the rail vibrations with the accelerometers, before and after the train pass-by. The performance of the proposed method is investigated with a set of pass-by measurements performed in Germany. The results seem to be promising when compared to reference data from TWINS, and the largest discrepancies occur above 1600 Hz and are attributed to plane waves radiated by the rail that so far have not been accounted for in the design of the filters.

  4. Relationship between internal medicine program board examination pass rates, accreditation standards, and program size.

    Science.gov (United States)

    Falcone, John L; Gonzalo, Jed D

    2014-01-19

    To determine Internal Medicine residency program compliance with the Accreditation Council for Graduate Medical Education 80% pass-rate standard and the correlation between residency program size and performance on the American Board of Internal Medicine Certifying Examination. Using a cross-sectional study design from 2010-2012 American Board of Internal Medicine Certifying Examination data of all Internal Medicine residency pro-grams, comparisons were made between program pass rates to the Accreditation Council for Graduate Medical Education pass-rate standard. To assess the correlation between program size and performance, a Spearman's rho was calculated. To evaluate program size and its relationship to the pass-rate standard, receiver operative characteristic curves were calculated. Of 372 Internal Medicine residency programs, 276 programs (74%) achieved a pass rate of =80%, surpassing the Accreditation Council for Graduate Medical Education minimum standard. A weak correlation was found between residency program size and pass rate for the three-year period (p=0.19, pInternal Medicine residency programs complied with Accreditation Council for Graduate Medical Education pass-rate standards, a quarter of the programs failed to meet this requirement. Program size is positively but weakly associated with American Board of Internal Medicine Certifying Examination performance, suggesting other unidentified variables significantly contribute to program performance.

  5. Relative survival of juvenile chinook salmon (Oncorhynchus tshawyischa) through a Bonneville dam on the Columbia River

    International Nuclear Information System (INIS)

    Ferguson, J.

    1993-01-01

    The Bonneville Dam second powerhouse bypass system for juvenile salmon has one 6.1-m submersible travelling screen in each intake of all eight turbines, for a total of 24 screens. These screens set up a hydraulic cushion that deflects juvenile salmon away from the turbine intakes and into vertical bulkhead slots, from which they exit by their own volition into a collection gallery that travels the length of the powerhouse to a dewatering station and the outlet. A multiple-year evaluation was conducted on the comparative survival of subyearling chinook salmon through various passage modes at the dam. Using this information, operational scenarios could then be formulated to provide additional juvenile protection while meeting power system demands. In the summer, the juvenile salmon that passed through the bypass system had significantly lower survival rates than upper and lower turbine, spillway, and downstream control groups. Predation by northern squawfish (Ptychocheilus oregonensis) was suspected to have been the cause of high mortalities among bypassed fish. No significant differences existed between survival rates of upper and lower turbine groups. 7 refs., 2 figs., 1 tab

  6. Use of first-pass radionuclide angiography for evaluating left-sided heart regurgitation

    International Nuclear Information System (INIS)

    Mantel, J.; Freidin, M.; Willens, H.; Rubenfire, M.; Bahl, R.; Ruskin, R.; Cascade, P.

    1986-01-01

    The first-pass radionuclide technique can be used to evaluate valvular regurgitation. Sixty-three patients were studied with cardiac catheterization and first-pass radionuclide angiography. The degree of regurgitation by cardiac catheterization was evaluated by using a ranking scale of 0-4, where 4 is severe regurgitation. The results were as follows: for nine patients, rank = 0, and percentage of regurgitation (mean +- SD) = 3.6 +- 5; for five patients, rank = 1 and percentage regurgitation = 15.8 +- 3; for 13 patients, rank = 2 and percentage regurgitation = 28.5 +- 14; for 16 patients, rank = 3 and percentage regurgitation = 41.5 +- 10; and for 19 patients, rank = 4 and percentage regurgitation 54.9 +- 13. A correlation coefficient of .90 between cardiac catheterization and the first-pass technique was calculated. The authors conclude that first-pass radionuclide angiography can quantitate valvular regurgitation and accurately differentiate between no, minimal, moderate, and severe valvular regurgitation

  7. High peak-power kilohertz laser system employing single-stage multi-pass amplification

    Science.gov (United States)

    Shan, Bing; Wang, Chun; Chang, Zenghu

    2006-05-23

    The present invention describes a technique for achieving high peak power output in a laser employing single-stage, multi-pass amplification. High gain is achieved by employing a very small "seed" beam diameter in gain medium, and maintaining the small beam diameter for multiple high-gain pre-amplification passes through a pumped gain medium, then leading the beam out of the amplifier cavity, changing the beam diameter and sending it back to the amplifier cavity for additional, high-power amplification passes through the gain medium. In these power amplification passes, the beam diameter in gain medium is increased and carefully matched to the pump laser's beam diameter for high efficiency extraction of energy from the pumped gain medium. A method of "grooming" the beam by means of a far-field spatial filter in the process of changing the beam size within the single-stage amplifier is also described.

  8. Caffeine-enhanced survival of radiation-sensitive, repair-deficient Chinese hamster cells

    International Nuclear Information System (INIS)

    Utsumi, H.; Elkind, M.M.

    1983-01-01

    A clone of V79 Chinese hamster cells (V79-AL162/S-10) with unique properties has been isolated after a challenge of parental cells (V79-AL162) with 1 mM ouabain. Compared with parental cells, or with other clones isolated after the ouabain challenge, these cells form smaller colonies, are more sensitive to both x rays and fission-spectrum neutrons, and respond atypically to a postirradiation treatment with caffeine. Their enhanced response to x rays results mainly from a large reduction in the shoulder of their survival curve, probably because in late S phase, the most resistant phase in the cell cycle, the survival curve of these cells has a reduced shoulder width. Caffeine, and to a lesser extent theophylline, added to the colony-forming medium immediately after exposure appreciably increases the width of the shoulder of these sensitive cells, whereas caffeine has the opposite effect on the response of normal V79 cells. Thus the unique response of the V79-AL162/S-10 cells to a radiation posttreatment with caffeine (increased survival) results from a net increase in their ability to repair damage that is otherwise lethal; caffeine treatment ordinarly prevents normal V79 cells from repairing damage that is only potentially lethal

  9. Energy savings from transit passes : an evaluation of the University at Buffalo NFTA transit pass program for students, faculty, and staff.

    Science.gov (United States)

    2014-04-01

    The University Transportation Research Center Region 2 supported a study entitled Connections Beyond Campus: An Evaluation of the Niagara Frontier Transportation : Authority University at Buffalo Transit Pass Program. Unlimited Access t...

  10. Ultra-compact Higher-Order-Mode Pass Filter in a Silicon Waveguide

    DEFF Research Database (Denmark)

    Guan, Xiaowei; Frandsen, Lars Hagedorn; Ding, Yunhong

    2015-01-01

    An 3.7 μm long higher-order-mode pass filter with an extinction ratio larger than 20 dB is demonstrated in a 1D corrugated silicon multimode waveguide......An 3.7 μm long higher-order-mode pass filter with an extinction ratio larger than 20 dB is demonstrated in a 1D corrugated silicon multimode waveguide...

  11. Continuum Mechanical Modelling of Skin-pass Rolling

    DEFF Research Database (Denmark)

    Kijima, Hideo; Bay, Niels

    2007-01-01

    The special contact conditions in skin-pass rolling of steel strip is analyzed by studying plane strain upsetting of thin sheet with low reduction applying long narrow tools and dry friction conditions. An extended sticking region is estimated by an elasto-plastic FEM analysis of the plane strain...

  12. Using Silence to "Pass": Embodiment and Interactional Categorization in a Diasporic Context

    Science.gov (United States)

    Wagner, Lauren

    2015-01-01

    This article posits that "passing" is a manipulation of ambiguously embodied characteristics, linguistic practice, and ratification by other speakers. I explore discourses and practices of "passing" by post-migrant generation, diasporically-resident Moroccans who seek to be unmarked by migration when bargaining in Moroccan…

  13. Nerve Growth Factor in Cancer Cell Death and Survival

    Energy Technology Data Exchange (ETDEWEB)

    Molloy, Niamh H.; Read, Danielle E.; Gorman, Adrienne M., E-mail: adrienne.gorman@nuigalway.ie [Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway (Ireland)

    2011-02-01

    One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we review the growing literature which shows that neurotrophins contribute to pro-survival signaling in many different types of cancer. In particular, nerve growth factor, the archetypal neurotrophin, has been shown to play a role in tumorigenesis over the past decade. Nerve growth factor mediates its effects through its two cognate receptors, TrkA, a receptor tyrosine kinase and p75{sup NTR}, a member of the death receptor superfamily. Depending on the tumor origin, pro-survival signaling can be mediated by TrkA receptors or by p75{sup NTR}. For example, in breast cancer the aberrant expression of nerve growth factor stimulates proliferative signaling through TrkA and pro-survival signaling through p75{sup NTR}. This latter signaling through p75{sup NTR} promotes increased resistance to the induction of cell death by chemotherapeutic treatments. In contrast, in prostate cells the p75{sup NTR} mediates cell death and prevents metastasis. In prostate cancer, expression of this receptor is lost, which contributes to tumor progression by allowing cells to survive, proliferate and metastasize. This review focuses on our current knowledge of neurotrophin signaling in cancer, with a particular emphasis on nerve growth factor regulation of cell death and survival in cancer.

  14. Challenge testing of gametes to enhance their viability

    DEFF Research Database (Denmark)

    Callesen, Henrik

    2010-01-01

    of survival mechanism that enables them to come through the process. The details of the mechanism remain unknown but, if identified, it could have immense potential as a new way to improve the viability of embryos produced by ART. However, few publications describe systematic ways to challenge test gametes...... and then to use the results as a basis for improving gamete viability. Furthermore, new methods to monitor the reactions of gametes to such challenge tests are needed. In the present review, these two issues are discussed, as are some of the conditions necessary before a challenge test protocol can be part...

  15. Stress Effects in Channel Catfish (Ictalurus punctatus) Fry on Pond Survival

    Science.gov (United States)

    Results from previous studies suggested that channel catfish (Ictalurus punctatus) fry that were housed in very high traffic areas from hatch until reaching 9 g in size were able to survive experimental challenge with Edwardsiella ictaluri better than siblings who were hatched and raised in very low...

  16. A distributed lumped active all-pass network configuration.

    Science.gov (United States)

    Huelsman, L. P.; Raghunath, S.

    1972-01-01

    In this correspondence a new and interesting distributed lumped active network configuration that realizes an all-pass network function is described. A design chart for determining the values of the network elements is included.

  17. The relationships between rugby ground pass accuracy and ...

    African Journals Online (AJOL)

    Kathryn van Boom

    2 Department of Physiotherapy, School of Therapeutic Sciences, Faculty of. Health Sciences ... upper body kinematics of the players, specifically the rotations of the torso and ..... relationships between the body movements and pass accuracy ...

  18. Latent Toxicity of Endothall to Anadromous Salmonids During Seawater Challenge.

    Science.gov (United States)

    Courter, Lauren A; Garrison, Thomas M; Courter, Ian I

    2016-05-01

    Limited evidence exists on the latent effects of toxicant exposure on the seawater adaptability of anadromous salmon and steelhead. It is unclear whether such an effect exists for the widely used and relatively non-toxic herbicide endothall. Coho salmon, Oncorhynchus kisutch (coho), Chinook salmon, O. tshawytscha (Chinook), and anadromous rainbow trout, O. mykiss (steelhead) were subjected to a 10-day seawater challenge following freshwater treatments [0-12 mg acid equivalent (a.e)./L at 96 h]. Mean survival resulted in 82 % (n = 225), 84 % (n = 133), 90 % (n = 73) and 59 % (n = 147) survival for 0, 3-5, 6-8, and 9-12 mg a.e./L, respectively. Our results indicate a lower toxicity threshold compared with previously reported acute toxicity results, but higher compared with previous seawater challenge studies. We demonstrate the utility of the seawater challenge assay to accurately define toxic effects of pesticides on salmonids with complex life-histories.

  19. Incentive Pass-through for Residential Solar Systems in California

    Energy Technology Data Exchange (ETDEWEB)

    Dong, C. G. [Univ. of Texas, Austin, TX (United States); Wiser, Ryan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rai, Varun [Univ. of Texas, Austin, TX (United States)

    2014-10-01

    The deployment of solar photovoltaic (PV) systems has grown rapidly over the last decade, partly because of various government incentives. In the United States, among the largest and longest-running incentives have been those established in California. Building on past research, this report addresses the still-unanswered question: to what degree have the direct PV incentives in California been passed through from installers to consumers? This report helps address this question by carefully examining the residential PV market in California (excluding a certain class of third-party-owned PV systems) and applying both a structural-modeling approach and a reduced-form regression analysis to estimate the incentive pass-through rate. The results suggest an average pass-through rate of direct incentives of nearly 100%, though with regional differences among California counties. While these results could have multiple explanations, they suggest a relatively competitive market and well-functioning subsidy program. Further analysis is required to determine whether similar results broadly apply to other states, to other customer segments, to all third-party-owned PV systems, or to all forms of financial incentives for solar (considering not only direct state subsidies, but also utility electric bill savings and federal tax incentives).

  20. Tropical field performance of dual-pass PV tray dryer

    Science.gov (United States)

    Iskandar, A. Noor; Ya'acob, M. E.; Anuar, M. S.

    2017-09-01

    Solar Photovoltaic technology has become the preferable solution in many countries around the globe to solve the ever increasing energy demand of the consumers. In line with the consumer need, food processing technology has huge potentials of integration with the renewable energy resources especially in drying process which consumes the highest electricity loads. Traditionally, the solar dryer technology was applied in agriculture and food industries utilizing the sun's energy for drying process, but this is highly dependable on the weather condition and surrounding factors. This work shares some field performance of the new design of portable dual-pass PV tray dryer for drying crops in an enclosed system. The dual-pass PV tray dryer encompass a lightweight aluminium box structure with dimensions of 1.1m (L) x 0.6m (W) x 0.2m (H) and can hold a load capacity of 300g - 3kg of crop depending on the types of the crops. Experiments of field performance monitoring were conducted in October -November 2016 which justifies a considerable reduction in time and crops quality improvement when using the dual-pass PV tray dryer as compared to direct-sun drying.

  1. Effectiveness of PETTLEP imager on performance of passing skill in volleyball.

    Science.gov (United States)

    Afrouzeh, M; Sohrabi, E; Haghkhan, A; Rowshani, F; Goharrokhi, S

    2015-01-01

    This study was conducted to compare the effectiveness of PETTLEP-based imagery, and traditional imagery interventions, on performance of passing skill in volleyball. 36 beginners male volleyball players (Mage =13.5 years, SD=0.55 years) with 5-6 months practice experience were randomly assigned to one of three groups: physical practice + PETTLEP imagery (PP+PI) (N.=15), physical practice + traditional imagery (N.=15), and physical practice only (PP; N.=15). Subjects in the PP+PI group applied the seven components of PETTLEP imagery training; whereas subjects in the PP+TI engaged in a relaxation session before imagery and used response laden motor imagery scripts. The two groups completed 15 minutes of imagery training followed immediately by 13 minutes of "passing" practice three times per week. The PP group completed only 13 minutes of "passing" practice three times per week. Each group performed its respective tasks for 7 weeks. A pre-test took place during the first practice session in which "passing" was assessed. After the 7-week practice program, a post-test took place followed by a retention test, one "no-practice" week later. All groups improved significantly (Pvolleyball when combined with physical practice.

  2. PENINGKATAN HASIL BELAJAR PASSING SEPAK BOLA MELALUI PERMAINAN PEMBURU BINATANG

    Directory of Open Access Journals (Sweden)

    Agung Setiawan

    2015-10-01

    Full Text Available The purpose of this study was to determine the learning outcome approach passing through playing soccer Beast Hunter on fourth grade students of SD Negeri Batuagung 1 Balapulang District of Tegal 2014. This study was conducted in PTK SD Negeri Batuagung 1 Balapulang District of Tegal, the samples in this study were fourth graders, amounting to 24 students. This research method is Classroom Action Research. This study uses 2 cycles. The results showed that the learning outcomes passing football played by using the approach of animals hunters have a positive impact as seen on mastery learning outcomes of students who exceed the predetermined KKM 75 has increased the mastery learning in the first cycle reaches 70.83%, while the second cycle mastery learning reaches 95.83%. It is concluded that learning football passing play tracker approach has a positive impact, which can improve learning outcomes, interest and motivation to learn.

  3. A double-pass interferometer for measurement of dimensional changes

    International Nuclear Information System (INIS)

    Ren, Dongmei; Lawton, K M; Miller, J A

    2008-01-01

    A double-pass interferometer was developed for measuring dimensional changes of materials in a nanoscale absolute interferometric dilatometer. This interferometer realized the double-ended measurement of a sample using a single-detection double-pass interference system. The nearly balanced design, in which the measurement beam and the reference beam have equal optical path lengths except for the path difference caused by the sample itself, makes this interferometer have high stability, which is verified by the measurement of a quasi-zero-length sample. The preliminary experiments and uncertainty analysis show that this interferometer should be able to measure dimensional changes with characteristic uncertainty at the nanometer level

  4. Survival of juvenile chinook salmon and coho salmon in the Roza Dam fish bypass and in downstream reaches of the Yakima River, Washington, 2016

    Science.gov (United States)

    Kock, Tobias J.; Perry, Russell W.; Hansen, Amy C.

    2016-12-22

    Estimates of juvenile salmon survival are important data for fishery managers in the Yakima River Basin. Radiotelemetry studies during 2012–14 showed that tagged juvenile Chinook salmon (Oncorhynchus tshawytscha) that passed through the fish bypass at Roza Dam had lower survival than fish that passed through other routes at the dam. That study also identified flow-survival relationships in the reaches between the Roza Dam tailrace and Sunnyside Dam. During 2012–14, survival also was estimated through reaches downstream of Sunnyside Dam, but generally, sample sizes were low and the estimates were imprecise. In 2016, we conducted an evaluation using acoustic cameras and acoustic telemetry to build on information collected during the previous study. The goal of the 2016 research was to identify areas where mortality occurs in the fish bypass at Roza Dam, and to estimate reach-specific survival in reaches downstream of the dam. The 2016 study included juvenile Chinook salmon and coho salmon (O. kisutch).Three acoustic cameras were used to observe fish behavior (1) near the entrances to the fish bypass, (2) at a midway point in the fish bypass (convergence vault), and (3) at the bypass outfall. In total, 504 hours of acoustic camera footage was collected at these locations. We determined that smolt-sized fish (95–170 millimeters [mm]) were present in the highest proportions at each location, but predator-sized fish (greater than 250 mm) also were present at each site. Fish presence generally peaked during nighttime hours and crepuscular periods, and was low during daytime hours. In the convergence vault, smolt-sized fish exhibited holding behavior patterns, which may explain why some fish delayed while passing through the bypass.Some of the acoustic-tagged fish were delayed in the fish bypass following release, but there was no evidence to suggest that they experienced higher mortality than fish that were released at the bypass outfall or downstream of the dam

  5. Survival associated pathway identification with group Lp penalized global AUC maximization

    Directory of Open Access Journals (Sweden)

    Liu Zhenqiu

    2010-08-01

    Full Text Available Abstract It has been demonstrated that genes in a cell do not act independently. They interact with one another to complete certain biological processes or to implement certain molecular functions. How to incorporate biological pathways or functional groups into the model and identify survival associated gene pathways is still a challenging problem. In this paper, we propose a novel iterative gradient based method for survival analysis with group Lp penalized global AUC summary maximization. Unlike LASSO, Lp (p 1. We first extend Lp for individual gene identification to group Lp penalty for pathway selection, and then develop a novel iterative gradient algorithm for penalized global AUC summary maximization (IGGAUCS. This method incorporates the genetic pathways into global AUC summary maximization and identifies survival associated pathways instead of individual genes. The tuning parameters are determined using 10-fold cross validation with training data only. The prediction performance is evaluated using test data. We apply the proposed method to survival outcome analysis with gene expression profile and identify multiple pathways simultaneously. Experimental results with simulation and gene expression data demonstrate that the proposed procedures can be used for identifying important biological pathways that are related to survival phenotype and for building a parsimonious model for predicting the survival times.

  6. Survival estimates for the passage of juvenile salmonids through Snake River dams and reservoirs, 1996. Annual report

    International Nuclear Information System (INIS)

    Smith, S.G.; Muir, W.D.; Hockersmith, E.E.; Achord, S.; Eppard, M.B.; Ruehle, T.E.; Williams, J.G.

    1998-02-01

    In 1996, the National Marine Fisheries Service and the University of Washington completed the fourth year of a multi-year study to estimate survival of juvenile salmonids (Oncorhynchus spp.) passing through dams and reservoirs on the Snake River. Actively migrating smolts were collected near the head of Lower Granite Reservoir and at Lower Granite Dam, tagged with passive integrated transponder (PIT) tags, and released to continue their downstream migration. Individual smolts were subsequently detected at PIT-tag detection facilities at Lower Granite, Little Goose, Lower Monumental, McNary, John Day and Bonneville Dams. Survival estimates were calculated using the Single-Release (SR) and Paired-Release (PR) Models. Timing of releases of tagged hatchery steelhead (O. mykiss) from the head of Lower Granite Reservoir and yearling chinook salmon (O. tshawytscha) from Lower Granite Dam in 1996 spanned the major portion of their juvenile migrations. Specific research objectives in 1996 were to (1) estimate reach and project survival in the Snake River using the Single-Release and Paired-Release Models throughout the yearling chinook salmon and steelhead migrations, (2) evaluate the performance of the survival-estimation models under prevailing operational and environmental conditions in the Snake River, and (3) synthesize results from the 4 years of the study to investigate relationships between survival probabilities, travel times, and environmental factors such as flow levels and water temperature

  7. Survival Estimates for the Passage of Juvenile Salmonids through Snake River Dams and Reservoirs, 1996 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Steven G.

    1998-02-01

    In 1996, the National Marine Fisheries Service and the University of Washington completed the fourth year of a multi-year study to estimate survival of juvenile salmonids (Oncorhynchus spp.) passing through dams and reservoirs on the Snake River. Actively migrating smolts were collected near the head of Lower Granite Reservoir and at Lower Granite Dam, tagged with passive integrated transponder (PIT) tags, and released to continue their downstream migration. Individual smolts were subsequently detected at PIT-tag detection facilities at Lower Granite, Little Goose, Lower Monumental, McNary, John Day and Bonneville Dams. Survival estimates were calculated using the Single-Release (SR) and Paired-Release (PR) Models. Timing of releases of tagged hatchery steelhead (O. mykiss) from the head of Lower Granite Reservoir and yearling chinook salmon (O. tshawytscha) from Lower Granite Dam in 1996 spanned the major portion of their juvenile migrations. Specific research objectives in 1996 were to (1) estimate reach and project survival in the Snake River using the Single-Release and Paired-Release Models throughout the yearling chinook salmon and steelhead migrations, (2) evaluate the performance of the survival-estimation models under prevailing operational and environmental conditions in the Snake River, and (3) synthesize results from the 4 years of the study to investigate relationships between survival probabilities, travel times, and environmental factors such as flow levels and water temperature.

  8. Succession and survival in psychotherapy organizations.

    Science.gov (United States)

    Khaleelee, Olya

    2008-11-01

    This paper examines the world of psychotherapy by applying a systemic and psychodynamic understanding of the family business as a way of understanding the dilemmas and challenges of leadership succession. Oedipal factors are explored as an important theme within the succession process. This exploration is set within the context of what function psychotherapy has performed in society over the last thirty years. The hypothesis is that the first generation of leaders aimed to provide containment for the individual citizen at a time of failed dependency in society. The suggestion is that this gave way to the primary task for the second generation, which has been to focus on the therapist in training. The challenge for the third generation is to develop a meaningful role for psychotherapy today and to ensure survival at a time when other shorter therapies such as CBT are gaining ascendancy over longer term psychoanalytic psychotherapy.

  9. The New Evangelisation and Adult Religious Education in Slovenia: Challenges and Possibilities

    Science.gov (United States)

    Stegu, Tadej

    2015-01-01

    The Catholic Church in Slovenia is facing the challenge of the new evangelisation in the area of religious education which, at present, is mainly confined to the parish catechesis. She recognises the urgent need to pass from the religious education of children to adult catechesis. The latter is already being implemented in various forms by a…

  10. A survivability model for ejection of green compacts in powder metallurgy technology

    Directory of Open Access Journals (Sweden)

    Payman Ahi

    2012-01-01

    Full Text Available Reliability and quality assurance have become major considerations in the design and manufacture of today’s parts and products. Survivability of green compact using powder metallurgy technology is considered as one of the major quality attributes in manufacturing systems today. During powder metallurgy (PM production, the compaction conditions and behavior of the metal powder dictate the stress and density distribution in the green compact prior to sintering. These parameters greatly influence the mechanical properties and overall strength of the final component. In order to improve these properties, higher compaction pressures are usually employed, which make unloading and ejection of green compacts more challenging, especially for the powder-compacted parts with relatively complicated shapes. This study looked at a mathematical survivability model concerning green compact characteristics in PM technology and the stress-strength failure model in reliability engineering. This model depicts the relationship between mechanical loads (stress during ejection, experimentally determined green strength and survivability of green compact. The resulting survivability is the probability that a green compact survives during and after ejection. This survivability model can be used as an efficient tool for selecting the appropriate parameters for the process planning stage in PM technology. A case study is presented here in order to demonstrate the application of the proposed survivability model.

  11. Ghrelin as a Survival Hormone.

    Science.gov (United States)

    Mani, Bharath K; Zigman, Jeffrey M

    2017-12-01

    Ghrelin administration induces food intake and body weight gain. Based on these actions, the ghrelin system was initially proposed as an antiobesity target. Subsequent studies using genetic mouse models have raised doubts about the role of the endogenous ghrelin system in mediating body weight homeostasis or obesity. However, this is not to say that the endogenous ghrelin system is not important metabolically or otherwise. Here we review an emerging concept in which the endogenous ghrelin system serves an essential function during extreme nutritional and psychological challenges to defend blood glucose, protect body weight, avoid exaggerated depression, and ultimately allow survival. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Analysis and Design of Binary Message-Passing Decoders

    DEFF Research Database (Denmark)

    Lechner, Gottfried; Pedersen, Troels; Kramer, Gerhard

    2012-01-01

    Binary message-passing decoders for low-density parity-check (LDPC) codes are studied by using extrinsic information transfer (EXIT) charts. The channel delivers hard or soft decisions and the variable node decoder performs all computations in the L-value domain. A hard decision channel results...... message-passing decoders. Finally, it is shown that errors on cycles consisting only of degree two and three variable nodes cannot be corrected and a necessary and sufficient condition for the existence of a cycle-free subgraph is derived....... in the well-know Gallager B algorithm, and increasing the output alphabet from hard decisions to two bits yields a gain of more than 1.0 dB in the required signal to noise ratio when using optimized codes. The code optimization requires adapting the mixing property of EXIT functions to the case of binary...

  13. Manuscripts as Evidence for the use of Classics in Education, c. 800–1200: Estimating the Randomness of Survival

    Directory of Open Access Journals (Sweden)

    Jaakko Tahkokallio

    2017-06-01

    Full Text Available Are the surviving copies of schooltexts representative of what was popularly used in schools in the medieval period? In other words, was the survival of these manuscripts a random or selective process? To approach this question, this article presents a series of comparisons between the numbers of manuscripts of different schooltexts. It demonstrates that the most popular schooltexts all survive in very similar numbers from each century, and that the typical number of copies varies from one century to another. The easiest explanation for such a survival pattern is to assume that the texts were produced in equal numbers and passed through a relatively random filter of losses. The article seeks to test this intuitive explanation by using a simple probability mathematical experiment. In addition, the article analyses how the numbers of surviving manuscripts relate to entries in medieval book lists and medieval library catalogues. This examination supports the interpretation that the survival of schooltexts was a relatively random process. In addition, comparison between medieval book lists and extant manuscripts advocates caution in using the book lists as evidence for the popularity of texts in the medieval centuries. Even though the catalogues provide snapshots of specific historical situations, this paper concludes that the mass of extant books is more likely to give us a realistic picture of the contemporary popularity of texts.

  14. Passage Distribution and Federal Columbia River Power System Survival for Steelhead Kelts Tagged Above and at Lower Granite Dam, Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Colotelo, Alison HA; Harnish, Ryan A.; Jones, Bryan W.; Hanson, Amanda C.; Trott, Donna M.; Greiner, Michael J.; McMichael, Geoffrey A.; Ham, Kenneth D.; Deng, Zhiqun; Brown, Richard S.; Weiland, Mark A.; Li, X.; Fu, Tao

    2014-03-28

    Steelhead (Oncorhynchus mykiss) populations have declined throughout their range in the last century and many populations, including those of the Snake River Basin are listed under the Endangered Species Act of 1973. The reasons for their decline are many and complex, but include habitat loss and degradation, overharvesting, and dam construction. The 2008 Biological Opinion calls for an increase in the abundance of female steelhead through an increase in iteroparity (i.e., repeat spawning) and this can be realized through a combination of reconditioning and in-river survival of migrating kelts. The goal of this study is to provide the data necessary to inform fisheries managers and dam operators of Snake River kelt migration patterns, survival, and routes of dam passage. Steelhead kelts (n = 487) were captured and implanted with acoustic transmitters and passive integrated transponder (PIT)-tags at the Lower Granite Dam (LGR) Juvenile Fish Facility and at weirs located in tributaries of the Snake and Clearwater rivers upstream of LGR. Kelts were monitored as they moved downstream through the Federal Columbia River Power System (FCRPS) by 15 autonomous and 3 cabled acoustic receiver arrays. Cabled receiver arrays deployed on the dam faces allowed for three-dimensional tracking of fish as they approached the dam face and were used to determine the route of dam passage. Overall, 27.3% of the kelts tagged in this study successfully migrated to Martin Bluff (rkm 126, as measured from the mouth of the Columbia River), which is located downstream of all FCRPS dams. Within individual river reaches, survival per kilometer estimates ranged from 0.958 to 0.999; the lowest estimates were observed in the immediate forebay of FCRPS dams. Steelhead kelts tagged in this study passed over the spillway routes (spillway weirs, traditional spill bays) in greater proportions and survived at higher rates compared to the few fish passed through powerhouse routes (turbines and juvenile

  15. Passage Distribution and Federal Columbia River Power System Survival for Steelhead Kelts Tagged Above and at Lower Granite Dam, Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Colotelo, Alison H.A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Harnish, Ryan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jones, Bryan W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hanson, Amanda C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Trott, Donna M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Greiner, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mcmichael, Geoffrey A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ham, Kenneth D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Zhiqun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Brown, Richard S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weiland, Mark A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Xinya [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fu, Tao [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-12-15

    Steelhead (Oncorhynchus mykiss) populations have declined throughout their range in the last century and many populations, including those of the Snake River Basin are listed under the Endangered Species Act of 1973. The reasons for their decline are many and complex, but include habitat loss and degradation, overharvesting, and dam construction. The 2008 Biological Opinion calls for an increase in the abundance of female steelhead through an increase in iteroparity (i.e., repeat spawning) and this can be realized through a combination of reconditioning and in-river survival of migrating kelts. The goal of this study is to provide the data necessary to inform fisheries managers and dam operators of Snake River kelt migration patterns, survival, and routes of dam passage. Steelhead kelts (n = 487) were captured and implanted with acoustic transmitters and passive integrated transponder (PIT)-tags at the Lower Granite Dam (LGR) Juvenile Fish Facility and at weirs located in tributaries of the Snake and Clearwater rivers upstream of LGR. Kelts were monitored as they moved downstream through the Federal Columbia River Power System (FCRPS) by 15 autonomous and 3 cabled acoustic receiver arrays. Cabled receiver arrays deployed on the dam faces allowed for three-dimensional tracking of fish as they approached the dam face and were used to determine the route of dam passage. Overall, 27.3% of the kelts tagged in this study successfully migrated to Martin Bluff (rkm 126, as measured from the mouth of the Columbia River), which is located downstream of all FCRPS dams. Within individual river reaches, survival per kilometer estimates ranged from 0.958 to 0.999; the lowest estimates were observed in the immediate forebay of FCRPS dams. Steelhead kelts tagged in this study passed over the spillway routes (spillway weirs, traditional spill bays) in greater proportions and survived at higher rates compared to the few fish passed through powerhouse routes (turbines and juvenile

  16. Galantamine is a novel post-exposure therapeutic against lethal VX challenge

    International Nuclear Information System (INIS)

    Hilmas, Corey J.; Poole, Melissa J.; Finneran, Kathryn; Clark, Matthew G.; Williams, Patrick T.

    2009-01-01

    The ability of galantamine hydrobromide (GAL HBr) treatment to antagonize O-ethyl-S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX)-induced lethality, impairment of muscle tension, and electroencephalographic (EEG) changes was assessed in guinea pigs. Guinea pigs were challenged with 16.8 μg/kg VX (2LD50). One min after challenge, animals were administered 0.5 mg/kg atropine sulfate (ATR) and 25 mg/kg pyridine-2-aldoxime methochloride (2-PAM). In addition, guinea pigs were given 0, 1, 2, 4, 8 or 10 mg/kg GAL as a post-exposure treatment immediately prior to ATR and 2-PAM. Animals were either monitored for 24-h survival, scheduled for electroencephalography (EEG) recording, or euthanized 60 min later for measurement of indirectly-elicited muscle tension in the hemidiaphragm. Post-exposure GAL therapy produced a dose-dependent increase in survival from lethal VX challenge. Optimal clinical benefits were observed in the presence of 10 mg/kg GAL, which led to 100% survival of VX-challenged guinea pigs. Based on muscle physiology studies, GAL post-exposure treatment protected the guinea pig diaphragm, the major effector muscle of respiration, from fatigue, tetanic fade, and muscular paralysis. Protection against the paralyzing effects of VX was dose-dependent. In EEG studies, GAL did not alter seizure onset for all doses tested. At the highest dose tested (10 mg/kg), GAL decreased seizure duration when administered as a post-exposure treatment 1 min after VX. GAL also reduced the high correlation associated between seizure activity and lethality after 2LD50 VX challenge. GAL may have additional benefits both centrally and peripherally that are unrelated to its established mechanism as a reversible acetylcholinesterase inhibitor (AChEI).

  17. Pass-transistor asynchronous sequential circuits

    Science.gov (United States)

    Whitaker, Sterling R.; Maki, Gary K.

    1989-01-01

    Design methods for asynchronous sequential pass-transistor circuits, which result in circuits that are hazard- and critical-race-free and which have added degrees of freedom for the input signals, are discussed. The design procedures are straightforward and easy to implement. Two single-transition-time state assignment methods are presented, and hardware bounds for each are established. A surprising result is that the hardware realizations for each next state variable and output variable is identical for a given flow table. Thus, a state machine with N states and M outputs can be constructed using a single layout replicated N + M times.

  18. TM-pass polarizer based on multilayer graphene polymer waveguide

    Science.gov (United States)

    Cai, Ke-su; Li, Yue-e.; Wei, Wen-jing; Mu, Xi-jiao; Ma, A.-ning; Wang, Zhong; Song, Dan-ming

    2018-05-01

    A TM-pass polarizer based on multilayer graphene polymer waveguide is proposed and theoretically analyzed. The mode properties, the extinction ratio, the insertion loss and the bandwidth are also discussed. The results show that a TM-pass polarizer, which only guides the TM mode, can be achieved by multilayer graphene polymer waveguide. With length of 150 μm, the proposed polarizer can achieve extinction ratio of 33 dB and insertion loss of 0.5 dB at optical wavelength of 1.55 μm. This device has an excellent performance, including large extinction ratio and low insertion loss within the spectral range from 1.45 μm to 1.6 μm.

  19. EXCHANGE RATE PASS-THROUGH, IMPORT PRICES AND INFLATION UNDER STRUCTURAL BREAKS

    Directory of Open Access Journals (Sweden)

    Arintoko Arintoko

    2011-09-01

    Full Text Available This research estimates the exchange rate pass-through (ERPT into import prices by applying an extension of the basic model of ERPT on Indonesia. It estimates models of cointegration and error-correction mechanism (ECM, with and without structural breaks. It uses the techniques of Zivot-Andrews and of Gregory-Hansen to test for structural breaks and cointegration with the structural breaks, respectively. The results show that with the control variables, inflation affects import prices and lower the pass-through for short term, in a condition of free floating exchange rate. In the short term, with the inclusion of structural breaks, significant inflation affects import prices and lowers the ERPT coefficient.  Keywords:    Exchange rate pass-through, inflation, structural breaks, cointegration, error-correction mechanismJEL classification numbers: C22, C32, E31, F41

  20. 9 CFR 312.3 - Official marks and devices to identify inspected and passed equine products.

    Science.gov (United States)

    2010-01-01

    ... inspected and passed equine products. 312.3 Section 312.3 Animals and Animal Products FOOD SAFETY AND... § 312.3 Official marks and devices to identify inspected and passed equine products. (a) The official... § 317.2 of this subchapter to identify inspected and passed mule and other (nonhorse) equine carcasses...

  1. Estimating natural recharge in San Gorgonio Pass watersheds, California, 1913–2012

    Science.gov (United States)

    Hevesi, Joseph A.; Christensen, Allen H.

    2015-12-21

    A daily precipitation-runoff model was developed to estimate spatially and temporally distributed recharge for groundwater basins in the San Gorgonio Pass area, southern California. The recharge estimates are needed to define transient boundary conditions for a groundwater-flow model being developed to evaluate the effects of pumping and climate on the long-term availability of groundwater. The area defined for estimating recharge is referred to as the San Gorgonio Pass watershed model (SGPWM) and includes three watersheds: San Timoteo Creek, Potrero Creek, and San Gorgonio River. The SGPWM was developed by using the U.S. Geological Survey INFILtration version 3.0 (INFILv3) model code used in previous studies of recharge in the southern California region, including the San Gorgonio Pass area. The SGPWM uses a 150-meter gridded discretization of the area of interest in order to account for spatial variability in climate and watershed characteristics. The high degree of spatial variability in climate and watershed characteristics in the San Gorgonio Pass area is caused, in part, by the high relief and rugged topography of the area.

  2. Multiple pass and multiple layer friction stir welding and material enhancement processes

    Science.gov (United States)

    Feng, Zhili [Knoxville, TN; David, Stan A [Knoxville, TN; Frederick, David Alan [Harriman, TN

    2010-07-27

    Processes for friction stir welding, typically for comparatively thick plate materials using multiple passes and multiple layers of a friction stir welding tool. In some embodiments a first portion of a fabrication preform and a second portion of the fabrication preform are placed adjacent to each other to form a joint, and there may be a groove adjacent the joint. The joint is welded and then, where a groove exists, a filler may be disposed in the groove, and the seams between the filler and the first and second portions of the fabrication preform may be friction stir welded. In some embodiments two portions of a fabrication preform are abutted to form a joint, where the joint may, for example, be a lap joint, a bevel joint or a butt joint. In some embodiments a plurality of passes of a friction stir welding tool may be used, with some passes welding from one side of a fabrication preform and other passes welding from the other side of the fabrication preform.

  3. A novel SFG structure for C-T high-pass filters

    DEFF Research Database (Denmark)

    Nielsen, Ivan Riis

    1993-01-01

    A signal flow graph (SFG) structure for simulating passive high-pass ladder filters, called the incremental integration structure, is proposed. The structure requires the use of integrators with nonintegrating inputs, and an implementation based on the MOSFET-C technique is discussed. The increme......A signal flow graph (SFG) structure for simulating passive high-pass ladder filters, called the incremental integration structure, is proposed. The structure requires the use of integrators with nonintegrating inputs, and an implementation based on the MOSFET-C technique is discussed....... The incremental integration structure is compared to the leapfrog and direct SFG simulation structures. Leapfrog high-pass filters are relatively simple and show good noise properties, but they are based on differentiators and thus stability problems exist. The direct SFG simulation method is based on integrators...... and has good stability properties, but it leads to a relatively high circuit complexity and a high noise level. However, the incremental integration structure inherits the low-noise properties of the leapfrog structure and the good stability of the direct SFG simulation method. A sixth-order elliptic high...

  4. Double Pass 595 nm Pulsed Dye Laser Does Not Enhance the Efficacy of Port Wine Stains Compared with Single Pass: A Randomized Comparison with Histological Examination.

    Science.gov (United States)

    Yu, Wenxin; Zhu, Jiafang; Wang, Lizhen; Qiu, Yajing; Chen, Yijie; Yang, Xi; Chang, Lei; Ma, Gang; Lin, Xiaoxi

    2018-03-27

    To compare the efficacy and safety of double-pass pulsed dye laser (DWL) and single-pass PDL (SWL) in treating virgin port wine stain (PWS). The increase in the extent of vascular damage attributed to the use of double-pass techniques for PWS remains inconclusive. A prospective, side-by-side comparison with a histological study for virgin PWS is still lacking. Twenty-one patients (11 flat PWS, 10 hypertrophic PWS) with untreated PWS underwent 3 treatments at 2-month intervals. Each PWS was divided into three treatment sites: SWL, DWL, and untreated control. Chromametric and visual evaluation of the efficacy and evaluation of side effects were conducted 3 months after final treatment. Biopsies were taken at the treated sites immediately posttreatment. Chromametric and visual evaluation suggested that DWL sites showed no significant improvement compared with SWL (p > 0.05) in treating PWS. The mean depth of photothermal damage to the vessels was limited to a maximum of 0.36-0.41 mm in both SWL and DWL sides. Permanent side effects were not observed in any patients. Double-pass PDL does not enhance PWS clearance. To improve the clearance of PWS lesions, either the depth of laser penetration should be increased or greater photothermal damage to vessels should be generated.

  5. The challenges and possibilities of public access defibrillation

    NARCIS (Netherlands)

    Ringh, Mattias; Hollenberg, Jacob; Palsgaard-Moeller, Thea; Svensson, Leif; Rosenqvist, Mårten; Lippert, Freddy K.; Wissenberg, Mads; Malta Hansen, Carolina; Claesson, Andreas; Viereck, Soren; Zijlstra, Jolande A.; Koster, Rudolph W.; Herlitz, Johan; Blom, Marieke T.; Kramer-Johansen, Jo; Tan, Hanno L.; Beesems, Steffie; Hulleman, Michiel; Olasveengen, Theresa M.; Folke, Fredrik

    2018-01-01

    Out-of-hospital cardiac arrest (OHCA) is a major health problem that affects approximately four hundred and thousand patients annually in the United States alone. It is a major challenge for the emergency medical system as decreased survival rates are directly proportional to the time delay from

  6. Survival analysis

    International Nuclear Information System (INIS)

    Badwe, R.A.

    1999-01-01

    The primary endpoint in the majority of the studies has been either disease recurrence or death. This kind of analysis requires a special method since all patients in the study experience the endpoint. The standard method for estimating such survival distribution is Kaplan Meier method. The survival function is defined as the proportion of individuals who survive beyond certain time. Multi-variate comparison for survival has been carried out with Cox's proportional hazard model

  7. Track-stitching using graphical models and message passing

    CSIR Research Space (South Africa)

    Van der Merwe, LJ

    2013-07-01

    Full Text Available In order to stitch tracks together, two tasks are required, namely tracking and track stitching. In this study track stitching is performed using a graphical model and message passing (belief propagation) approach. Tracks are modelled as nodes in a...

  8. Survival Estimates for the Passage of Juvenile Chinook Salmon through Snake River Dams and Reservoirs, 1993 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Iwamoto, Robert N.; Sandford, Benjamin P.; McIntyre, Kenneth W.

    1994-04-01

    A pilot study was conducted to estimate survival of hatchery-reared yearling chinook salmon through dams and reservoirs on the Snake River. The goals of the study were to: (1) field test and evaluate the Single-Release, Modified-Single-Release, and Paired-Release Models for the estimation of survival probabilities through sections of a river and hydroelectric projects; (2) identify operational and logistical constraints to the execution of these models; and (3) determine the usefulness of the models in providing estimates of survival probabilities. Field testing indicated that the numbers of hatchery-reared yearling chinook salmon needed for accurate survival estimates could be collected at different areas with available gear and methods. For the primary evaluation, seven replicates of 830 to 1,442 hatchery-reared yearling chinook salmon were purse-seined from Lower Granite Reservoir, PIT tagged, and released near Nisqually John boat landing (River Kilometer 726). Secondary releases of PIT-tagged smolts were made at Lower Granite Dam to estimate survival of fish passing through turbines and after detection in the bypass system. Similar secondary releases were made at Little Goose Dam, but with additional releases through the spillway. Based on the success of the 1993 pilot study, the authors believe that the Single-Release and Paired-Release Models will provide accurate estimates of juvenile salmonid passage survival for individual river sections, reservoirs, and hydroelectric projects in the Columbia and Snake Rivers.

  9. Survival estimates for the passage of juvenile chinook salmon through Snake River dams and reservoirs. Annual report 1993

    International Nuclear Information System (INIS)

    Iwamoto, R.N.; Muir, W.D.; Sandford, B.P.; McIntyre, K.W.; Frost, D.A.; Williams, J.G.; Smith, S.G.; Skalski, J.R.

    1994-04-01

    A pilot study was conducted to estimate survival of hatchery-reared yearling chinook salmon through dams and reservoirs on the Snake River. The goals of the study were to: (1) field test and evaluate the Single-Release, Modified-Single-Release, and Paired-Release Models for the estimation of survival probabilities through sections of a river and hydroelectric projects; (2) identify operational and logistical constraints to the execution of these models; and (3) determine the usefulness of the models in providing estimates of survival probabilities. Field testing indicated that the numbers of hatchery-reared yearling chinook salmon needed for accurate survival estimates could be collected at different areas with available gear and methods. For the primary evaluation, seven replicates of 830 to 1,442 hatchery-reared yearling chinook salmon were purse-seined from Lower Granite Reservoir, PIT tagged, and released near Nisqually John boat landing (River Kilometer 726). Secondary releases of PIT-tagged smolts were made at Lower Granite Dam to estimate survival of fish passing through turbines and after detection in the bypass system. Similar secondary releases were made at Little Goose Dam, but with additional releases through the spillway. Based on the success of the 1993 pilot study, the authors believe that the Single-Release and Paired-Release Models will provide accurate estimates of juvenile salmonid passage survival for individual river sections, reservoirs, and hydroelectric projects in the Columbia and Snake Rivers

  10. Multiparametric analysis of magnetic resonance images for glioma grading and patient survival time prediction

    International Nuclear Information System (INIS)

    Garzon, Benjamin; Emblem, Kyrre E.; Mouridsen, Kim; Nedregaard, Baard; Due-Toennessen, Paulina; Nome, Terje; Hald, John K.; Bjoernerud, Atle; Haaberg, Asta K.; Kvinnsland, Yngve

    2011-01-01

    Background. A systematic comparison of magnetic resonance imaging (MRI) options for glioma diagnosis is lacking. Purpose. To investigate multiple MR-derived image features with respect to diagnostic accuracy in tumor grading and survival prediction in glioma patients. Material and Methods. T1 pre- and post-contrast, T2 and dynamic susceptibility contrast scans of 74 glioma patients with histologically confirmed grade were acquired. For each patient, a set of statistical features was obtained from the parametric maps derived from the original images, in a region-of-interest encompassing the tumor volume. A forward stepwise selection procedure was used to find the best combinations of features for grade prediction with a cross-validated logistic model and survival time prediction with a cox proportional-hazards regression. Results. Presence/absence of enhancement paired with kurtosis of the FM (first moment of the first-pass curve) was the feature combination that best predicted tumor grade (grade II vs. grade III-IV; median AUC 0.96), with the main contribution being due to the first of the features. A lower predictive value (median AUC = 0.82) was obtained when grade IV tumors were excluded. Presence/absence of enhancement alone was the best predictor for survival time, and the regression was significant (P < 0.0001). Conclusion. Presence/absence of enhancement, reflecting transendothelial leakage, was the feature with highest predictive value for grade and survival time in glioma patients

  11. Multiparametric analysis of magnetic resonance images for glioma grading and patient survival time prediction

    Energy Technology Data Exchange (ETDEWEB)

    Garzon, Benjamin (Dept. of Circulation and Medical Imaging, NTNU, Trondheim (Norway)), email: benjamin.garzon@ntnu.no; Emblem, Kyrre E. (The Interventional Center, Rikshospitalet, Oslo Univ. Hospital, Oslo (Norway); Dept. of Radiology, MGH-HST AA Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston (United States)); Mouridsen, Kim (Center of Functionally Integrative Neuroscience, Aarhus Univ., Aarhus (Denmark)); Nedregaard, Baard; Due-Toennessen, Paulina; Nome, Terje; Hald, John K. (Dept. of Radiology and Nuclear Medicine, Rikshospitalet, Oslo Univ. Hospital, Oslo (Norway)); Bjoernerud, Atle (The Interventional Center, Rikshospitalet, Oslo Univ. Hospital, Oslo (Norway)); Haaberg, Asta K. (Dept. of Circulation and Medical Imaging, NTNU, Trondheim (Norway); Dept. of Medical Imaging, St Olav' s Hospital, Trondheim (Norway)); Kvinnsland, Yngve (NordicImagingLab, Bergen (Norway))

    2011-11-15

    Background. A systematic comparison of magnetic resonance imaging (MRI) options for glioma diagnosis is lacking. Purpose. To investigate multiple MR-derived image features with respect to diagnostic accuracy in tumor grading and survival prediction in glioma patients. Material and Methods. T1 pre- and post-contrast, T2 and dynamic susceptibility contrast scans of 74 glioma patients with histologically confirmed grade were acquired. For each patient, a set of statistical features was obtained from the parametric maps derived from the original images, in a region-of-interest encompassing the tumor volume. A forward stepwise selection procedure was used to find the best combinations of features for grade prediction with a cross-validated logistic model and survival time prediction with a cox proportional-hazards regression. Results. Presence/absence of enhancement paired with kurtosis of the FM (first moment of the first-pass curve) was the feature combination that best predicted tumor grade (grade II vs. grade III-IV; median AUC 0.96), with the main contribution being due to the first of the features. A lower predictive value (median AUC = 0.82) was obtained when grade IV tumors were excluded. Presence/absence of enhancement alone was the best predictor for survival time, and the regression was significant (P < 0.0001). Conclusion. Presence/absence of enhancement, reflecting transendothelial leakage, was the feature with highest predictive value for grade and survival time in glioma patients

  12. Number of Migration Scenarios Passing through each HUC (future)

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forest dwelling neotropical migratory birds require intact forested stopovers during migration. The number of paths that pass through a HUC highlight that huc's...

  13. Vehicle dynamic effects in the course of passing over turnouts

    Directory of Open Access Journals (Sweden)

    Zelenka J.

    2007-11-01

    Full Text Available For the quantification of vehicle dynamic effects at passing over turnouts at a higher speed there was developed a methodology for evaluating of acceleration measured on vehicle axle boxes in the year 2003. The methodology is based on statistical evaluation of lateral and vertical acceleration measured values at passing over both critical parts of a turnout (tongue, frog. The created methodology was used for investigation of vehicle dynamic effects by running at speed up to 230 km/h in the year 2004 in terms of high speed tests of tilting-body unit class 680 CD. There was found relatively high values of dynamic effects already at a speed 160 km/h. In terms of tilting-body unit class 680 tests at a higher speed in curves of chosen track lines of 1st and 2nd corridor of Czech Railways there was carried out also verification of curved turnouts state according to methodology mentioned above with a view to possibility of speed increasing at curved throats of chosen stations. Lateral vehicle dynamic effects at passing over a curved turnout frog area were evaluated. There were carried out simulation calculations of vehicle passing over a turnout based on measured geometric parameters of wheelset as well as chosen turnouts. Results of the calculations were compared with measurements. The increased vehicle dynamic effects found in pulsed beats character influence negatively the turnouts part (not only wheel contacting parts as well as operating life all unsuspended parts of vehicles.

  14. Evaluating low pass filters on SPECT reconstructed cardiac orientation estimation

    Science.gov (United States)

    Dwivedi, Shekhar

    2009-02-01

    Low pass filters can affect the quality of clinical SPECT images by smoothing. Appropriate filter and parameter selection leads to optimum smoothing that leads to a better quantification followed by correct diagnosis and accurate interpretation by the physician. This study aims at evaluating the low pass filters on SPECT reconstruction algorithms. Criteria for evaluating the filters are estimating the SPECT reconstructed cardiac azimuth and elevation angle. Low pass filters studied are butterworth, gaussian, hamming, hanning and parzen. Experiments are conducted using three reconstruction algorithms, FBP (filtered back projection), MLEM (maximum likelihood expectation maximization) and OSEM (ordered subsets expectation maximization), on four gated cardiac patient projections (two patients with stress and rest projections). Each filter is applied with varying cutoff and order for each reconstruction algorithm (only butterworth used for MLEM and OSEM). The azimuth and elevation angles are calculated from the reconstructed volume and the variation observed in the angles with varying filter parameters is reported. Our results demonstrate that behavior of hamming, hanning and parzen filter (used with FBP) with varying cutoff is similar for all the datasets. Butterworth filter (cutoff > 0.4) behaves in a similar fashion for all the datasets using all the algorithms whereas with OSEM for a cutoff < 0.4, it fails to generate cardiac orientation due to oversmoothing, and gives an unstable response with FBP and MLEM. This study on evaluating effect of low pass filter cutoff and order on cardiac orientation using three different reconstruction algorithms provides an interesting insight into optimal selection of filter parameters.

  15. Rethinking plant functional types in Earth System Models: pan-tropical analysis of tree survival across environmental gradients

    Science.gov (United States)

    Johnson, D. J.; Needham, J.; Xu, C.; Davies, S. J.; Bunyavejchewin, S.; Giardina, C. P.; Condit, R.; Cordell, S.; Litton, C. M.; Hubbell, S.; Kassim, A. R. B.; Shawn, L. K. Y.; Nasardin, M. B.; Ong, P.; Ostertag, R.; Sack, L.; Tan, S. K. S.; Yap, S.; McDowell, N. G.; McMahon, S.

    2016-12-01

    Terrestrial carbon cycling is a function of the growth and survival of trees. Current model representations of tree growth and survival at a global scale rely on coarse plant functional traits that are parameterized very generally. In view of the large biodiversity in the tropical forests, it is important that we account for the functional diversity in order to better predict tropical forest responses to future climate changes. Several next generation Earth System Models are moving towards a size-structured, trait-based approach to modelling vegetation globally, but the challenge of which and how many traits are necessary to capture forest complexity remains. Additionally, the challenge of collecting sufficient trait data to describe the vast species richness of tropical forests is enormous. We propose a more fundamental approach to these problems by characterizing forests by their patterns of survival. We expect our approach to distill real-world tree survival into a reasonable number of functional types. Using 10 large-area tropical forest plots that span geographic, edaphic and climatic gradients, we model tree survival as a function of tree size for hundreds of species. We found surprisingly few categories of size-survival functions emerge. This indicates some fundamental strategies at play across diverse forests to constrain the range of possible size-survival functions. Initial cluster analysis indicates that four to eight functional forms are necessary to describe variation in size-survival relations. Temporal variation in size-survival functions can be related to local environmental variation, allowing us to parameterize how demographically similar groups of species respond to perturbations in the ecosystem. We believe this methodology will yield a synthetic approach to classifying forest systems that will greatly reduce uncertainty and complexity in global vegetation models.

  16. Candida albicans survival and biofilm formation under starvation conditions.

    Science.gov (United States)

    Ning, Y; Hu, X; Ling, J; Du, Y; Liu, J; Liu, H; Peng, Z

    2013-01-01

    To investigate the survival and biofilm formation capacity of Candida albicans in starvation and under anaerobic conditions. Candida albicans growth and survival were monitored in vitro for up to 8 months. Fungal suspensions from late exponential, stationary and starvation phases were incubated on human dentine, polystyrene and glass slides. Scanning electron microscopy (SEM) was used to observe the process of biofilm formation. 2,3-bis(2-Methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxyanilide inner salt (XTT) reduction assay was performed to quantify the biofilm formation capability, and confocal laser scanning microscopy (CLSM) was used to study and make semi-quantitative comparisons of the ultrastructure of biofilms formed on human dentine. 'XTT bioactivity' and 'COMSTAT results' were analysed by two-way analysis of variance (ANOVA) and one-way ANOVA, respectively. Candida albicans survived for over six months. SEM demonstrated that starving C. albicans produced mature biofilms on different substrata. C. albicans of the same growth phase incubated on human dentine displayed significantly higher biofilm formation capability than on polystyrene or glass slides (P roughness coefficient and surface/volume ratio (P < 0.05). Candida albicans cells can survive and form biofilms in anaerobic and nutrient-limited conditions and may pose a treatment challenge. © 2012 International Endodontic Journal.

  17. ICRF heating of passing ions in a thermal barrier tandem mirror

    International Nuclear Information System (INIS)

    Molvik, A.W.; Dimonte, G.; Campbell, R.; Barter, J.; Cummins, W.F.; Falabella, S.; Poulsen, P.

    1985-05-01

    Ion heating is used in the central cells of tandem mirrors to reduce the collisional trapping of passing ions in the end cell thermal barriers. In this paper, we reevaluate ICRF heating of the TMX-U central cell in two limits. The first we term isotropic, because we impose the condition that ions heated in the perpendicular direction be confined for at least one 90 0 scattering time, thereby heating the passing ions. The second we call anisotropic heating. It uses higher ICRF power to mirror trap a majority of the ions near the midplane, thereby reducing the density and collisionality of passing ions. Anisotropic heating has the advantage of increasing with ICRF power, whereas isotropic heating is limited by ion collisionality. Both techniques require gas fueling near the central cell midplane, with an ion cyclotron resonance toward each end cell to heat the cold ions

  18. The Effects on Soccer Passing Skills When Warming Up with Two Different Sized Soccer Balls

    Science.gov (United States)

    Burcak, Keskin

    2015-01-01

    The purpose of the present research is studying the effects of warm-up with two different sizes of balls on passing skills. Loughborough Soccer Passing Test (LSPT) was conducted on 28 non-elite football players, who participated in the present research for 10 training days. LSPT is a passing skill protocol established on completing 16 passes…

  19. Common pass decentered annular ring resonator

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, D. A.; Waite, T. R.

    1985-04-30

    An optical resonator having an annular cylindrical gain region for use in a chemical laser or the like in which two ring-shaped mirrors having substantially conical reflecting surfaces are spaced apart along a common axis of revolution of the respective conical surfaces. A central conical mirror reflects incident light directed along said axis radially outwardly to the reflecting surface of a first one of the ring-shaped mirrors. The radial light rays are reflected by the first ring mirror to the second ring mirror within an annular cylindrical volume concentric with said common axis and forming a gain region. Light rays impinging on the second ring mirror are reflected to diametrically opposite points on the same conical mirror surfaces and back to the first ring mirror through the same annular cylindrical volume. The return rays are then reflected by the conical mirror surface of the first ring mirror back to the central conical mirror. The mirror surfaces are angled such that the return rays are reflected back along the common axis by the central mirror in a concentric annular cylindrical volume. A scraper mirror having a central opening centered on said axis and an offset opening reflects all but the rays passing through the two openings in an output beam. The rays passing through the second opening are reflected back through the first opening to provide feedback.

  20. Performance and cost benefits analysis of double-pass solar collector with and without fins

    International Nuclear Information System (INIS)

    Fudholi, Ahmad; Sopian, Kamaruzzaman; Ruslan, Mohd Hafidz; Othman, Mohd Yusof

    2013-01-01

    Highlights: • The thermal performances and cost analysis of the double-pass solar collector with and without fins absorber were discussed. • The theoretical and experimental study on the double-pass solar air collector with and without fins absorber was conducted. • The ratio of AC/AEG or the cost benefit ratio was presented. • The double-pass solar collector with fins absorber is more cost-effective compared to without fins absorber. - Abstract: The performance and cost benefit analysis of double-pass solar collector with and without fins have been conducted. The theoretical model using steady state analysis has been developed and compared with the experimental results. The performance curves of the double-pass solar collector with and without fins, which included the effects of mass flow rate and solar intensity on the thermal efficiency of the solar collector, were obtained. Results indicated that the thermal efficiency is proportional to the solar intensity at a specific mass flow rate. The thermal efficiency increased by 9% at a solar intensity of 425–790 W/m 2 and mass flow rate of 0.09 kg/s. The theoretical and experimental analysis showed a similar trend as well as close agreement. Moreover, a cost-effectiveness model has been developed examine the cost benefit ratio of double-pass solar collector with and without fins. Evaluation of the annual cost (AC) and the annual energy gain (AEG) of the collector were also performed. The results show that the double-pass solar collector with fins is more cost-effective compared to the double-pass solar collector without fins for mass flow rate of 0.01–0.07 kg/s. Also, simulations were obtained for the double-pass solar collector with fins at Nusselt number of 5.42–36.21. The energy efficiency of collector increases with the increase of Nusselt number. The results show that by increasing the Nusselt number simultaneously would drop the outlet temperature at any solar intensity. Increase in Nusselt number

  1. Protocol-Based Verification of Message-Passing Parallel Programs

    DEFF Research Database (Denmark)

    López-Acosta, Hugo-Andrés; Eduardo R. B. Marques, Eduardo R. B.; Martins, Francisco

    2015-01-01

    We present ParTypes, a type-based methodology for the verification of Message Passing Interface (MPI) programs written in the C programming language. The aim is to statically verify programs against protocol specifications, enforcing properties such as fidelity and absence of deadlocks. We develo...

  2. The ISO 5-pass authentication in χ-Spaces

    DEFF Research Database (Denmark)

    Cáccamo, Mario J.; Crazzolara, Federico; Milicia, Giuseppe

    2002-01-01

    We implement the ISO 5-pass authentication protocol and study its correctness using the χ-Space framework. χ-Spaces is a novel domain specific programming language designed for developing protocols and in particular security protocols. χ-Spaces programming language is an implementation of SPL...

  3. 48 CFR 652.237-71 - Identification/Building Pass.

    Science.gov (United States)

    2010-10-01

    ..., Information Security Programs Division, Industrial Security Branch (DS/ISP/INB) on its cleared employees..., Information Security Programs Division, Industrial Security Branch (DS/ISP/INB): (i) SF-85P, Questionnaire for... Pass (APR 2004) (a) Contractors working in domestic facilities who already possess a security clearance...

  4. 20 CFR 416.2099 - Compliance with pass-along.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Compliance with pass-along. 416.2099 Section 416.2099 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED State Supplementation Provisions; Agreement; Payments § 416.2099 Compliance with...

  5. Structural Controls of the Emerson Pass Geothermal System, Washoe County, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Ryan B [Nevada Bureau of Mines and Geology, University of Nevada, Reno; Faulds, James E [Nevada Bureau of Mines and Geology, University of Nevada, Reno

    2012-09-30

    We have conducted a detailed geologic study to better characterize a blind geothermal system in Emerson Pass on the Pyramid Lake Paiute Tribe Reservation, western Nevada. A thermal anomaly was discovered in Emerson Pass by use of 2 m temperature surveys deployed within a structurally favorable setting and proximal to surface features indicative of geothermal activity. The anomaly lies at the western edge of a broad left step at the northeast end of Pyramid Lake between the north- to north-northeast-striking, west-dipping, Fox and Lake Range normal faults. The 2-m temperature surveys have defined a N-S elongate thermal anomaly that has a maximum recorded temperature of ~60°C and resides on a north- to north-northeaststriking fault. Travertine mounds, chalcedonic silica veins, and silica cemented Pleistocene lacustrine gravels in Emerson Pass indicate a robust geothermal system active at the surface in the recent past. Structural complexity and spatial heterogeneities of the strain and stress field have developed in the step-over region, but kinematic data suggest a WNW-trending (~280° azimuth) extension direction. The geothermal system is likely hosted in Emerson Pass as a result of enhanced permeability generated by the intersection of two oppositely dipping, southward terminating north- to north-northwest-striking (Fox Range fault) and northnortheast- striking faults.

  6. Rapid Urbanization and the Aspiration and Challenge of Second-Generation Urban-Rural Migrants

    Science.gov (United States)

    Jialing, Han

    2012-01-01

    This article examines the features of second-generation rural migrants and the challenges facing them in terms of schooling and employment. There is a gap that is hard for them to step over: barriers against social inclusion. The article concludes that poverty tends to pass on to the next generation and fossilize. Therefore, it is vital to…

  7. Connecticut church passes genetics resolution.

    Science.gov (United States)

    Culliton, B J

    1984-11-09

    The Connecticut Conference of the United Church of Christ, which represents the largest Protestant denomination in the state, has passed a resolution affirming an ethical duty to do research on human gene therapy and is planning to form local church groups to study the scientific and ethical issues involved. The resolution is intended to counter an earlier one proposed by Jeremy Rifkin to ban all efforts at engineering specific traits into the human germline. The Rifkin proposal had been endorsed by a large number of religious leaders, including the head of the U.S. United Church of Christ, but was subsequently characterized by many of the church leaders as overly restrictive.

  8. Live related kidney transplant: a rare case report of graft survival 22 ...

    African Journals Online (AJOL)

    Kidney transplant is the most appropriate renal replacement therapy in terms of survival, quality of life and long term cost. We report 81 years old Nigerian whose kidney transplant lasted for 22 years. He encountered various challenges including complications relating to the long term impact of immunosuppression and ...

  9. Is a more stable exchange rate associated with reduced exchange rate pass-through?

    OpenAIRE

    Mark J. Holmes

    2007-01-01

    Pass-through from the nominal effective exchange rate to import prices is modelled within a regime-switching environment. Evidence suggests that exchange rate pass through can be characterised as regime-specific where the probability of switching between regimes is influenced by the extent of exchange rate volatility.

  10. Single and double pass solar air heaters with wire mesh as packing bed

    Energy Technology Data Exchange (ETDEWEB)

    Aldabbagh, L.B.Y.; Egelioglu, F. [Mechanical Engineering Department, Eastern Mediterranean University, Magosa, Mersin 10 (Turkey); Ilkan, M. [School of Computing and Tecnology, Eastern Mediterranean University, Magosa, Mersin 10 (Turkey)

    2010-09-15

    The thermal performances of single and double pass solar air heaters with steel wire mesh layers are used instead of a flat absorber plate are investigated experimentally. The effects of mass flow rate of air on the outlet temperature and thermal efficiency were studied. The results indicate that the efficiency increases with increasing the mass flow rate for the range of the flow rate used in this work between 0.012 and 0.038 kg/s. For the same flow rate, the efficiency of the double pass is found to be higher than the single pass by 34-45%. Moreover, the maximum efficiencies obtained for the single and the double pass air collectors are 45.93 and 83.65% respectively for the mass flow rate of 0.038 kg/s. Comparison of the results of a packed bed collector with those of a conventional collector shows a substantial enhancement in the thermal efficiency. (author)

  11. Decision aids for enhancing intergovernmental interactions: The Prenotification Analysis Support System (PASS)

    International Nuclear Information System (INIS)

    Lester, M.; Liebow, E.; Holm, J.

    1994-01-01

    The Department of Energy (DOE) plans to honor its commitment to government-to-government interactions by providing advance notice of DOE spent fuel and high-level waste shipments to Indian tribes whose jurisdictions are crossed by or adjacent to transportation routes. The tribes are important contributors to a regional response network, and providing tribes with advance notice of DOE shipping plans marks the start -- not the end -- of direct, government-to-government interactions with DOE. The Tribal Prenotification Analysis Support System (PASS) is being developed for the Office of Special Programs within the Department's Office of Environmental Restoration and Waste Management. PASS will help DOE-Headquarters to coordinate field office activities and provide technical and institutional support to the DOE field offices. PASS is designed to be used by anyone with minimum computer literacy and having contemporary computer hardware and software. It uses on-screen maps to choose and display a shipment route, and to display the tribal jurisdictions. With forms that are easy to understand, it provides information about each jurisdiction and points of contact. PASS records all contacts, commitments made, and actions taken

  12. Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax

    Science.gov (United States)

    Yamamoto, Brent J.; Shadiack, Annette M.; Carpenter, Sarah; Sanford, Daniel; Henning, Lisa N.; Gonzales, Nestor; O'Connor, Edward; Casey, Leslie S.

    2016-01-01

    The Centers for Disease Control and Prevention recommend adjunctive antitoxins when systemic anthrax is suspected. Obiltoxaximab, a monoclonal antibody against protective antigen (PA), is approved for treatment of inhalational anthrax in combination with antibiotics and for prophylaxis when alternative therapies are not available. The impact of toxin neutralization with obiltoxaximab during pre- and postexposure prophylaxis was explored, and efficacy results that supported the prophylaxis indication are presented here. New Zealand White rabbits and cynomolgus macaques received obiltoxaximab as a single intramuscular or intravenous dose of 2 to 16 mg/kg of body weight at various times relative to Bacillus anthracis aerosol spore challenge. The primary endpoint was survival, and effect of treatment timing was explored. In rabbits, obiltoxaximab administration 9 h postchallenge singly or combined with a 5-day levofloxacin regimen protected 89% to 100% of animals compared to 33% with levofloxacin monotherapy. In cynomolgus macaques, a single intramuscular dose of 16 mg/kg obiltoxaximab led to 100% survival when given 1 to 3 days preexposure and 83% to 100% survival when given 18 to 24 h postexposure and prior to systemic bacteremia onset. Obiltoxaximab administration after bacteremia onset resulted in lower (25% to 50%) survival rates reflective of treatment setting. Prophylactic administration of obiltoxaximab before spore challenge or to spore-challenged animals before systemic bacterial dissemination is efficacious in promoting survival, ameliorating toxemia, and inhibiting bacterial spread to the periphery. PMID:27431219

  13. Network survivability performance

    Science.gov (United States)

    1993-11-01

    This technical report has been developed to address the survivability of telecommunications networks including services. It responds to the need for a common understanding of, and assessment techniques for network survivability, availability, integrity, and reliability. It provides a basis for designing and operating telecommunications networks to user expectations for network survivability and a foundation for continuing industry activities in the subject area. This report focuses on the survivability of both public and private networks and covers a wide range of users. Two frameworks are established for quantifying and categorizing service outages, and for classifying network survivability techniques and measures. The performance of the network survivability techniques is considered; however, recommended objectives are not established for network survivability performance.

  14. Adélie penguin survival: age structure, temporal variability and environmental influences.

    Science.gov (United States)

    Emmerson, Louise; Southwell, Colin

    2011-12-01

    The driving factors of survival, a key demographic process, have been particularly challenging to study, especially for winter migratory species such as the Adélie penguin (Pygoscelis adeliae). While winter environmental conditions clearly influence Antarctic seabird survival, it has been unclear to which environmental features they are most likely to respond. Here, we examine the influence of environmental fluctuations, broad climatic conditions and the success of the breeding season prior to winter on annual survival of an Adélie penguin population using mark-recapture models based on penguin tag and resight data over a 16-year period. This analysis required an extension to the basic Cormack-Jolly-Seber model by incorporating age structure in recapture and survival sub-models. By including model covariates, we show that survival of older penguins is primarily related to the amount and concentration of ice present in their winter foraging grounds. In contrast, fledgling and yearling survival depended on other factors in addition to the physical marine environment and outcomes of the previous breeding season, but we were unable to determine what these were. The relationship between sea-ice and survival differed with penguin age: extensive ice during the return journey to breeding colonies was detrimental to survival for the younger penguins, whereas either too little or too much ice (between 15 and 80% cover) in the winter foraging grounds was detrimental for adults. Our results demonstrate that predictions of Adélie penguin survival can be improved by taking into account penguin age, prior breeding conditions and environmental features.

  15. Deuterium pass through target

    International Nuclear Information System (INIS)

    Alger, D.L.

    1975-01-01

    A neutron emitting target is described for use in neutron generating apparatus including a deuteron source and an accelerator vacuum chamber. The target consists of a tritium-containing target layer, a deuteron accumulation layer, and a target support containing passages providing communication between the accumulation layer and portions of the surface of the support exposed to the accelerator vacuum chamber. With this arrangement, deuterons passing through the target layer and implanting in and diffusing through the accumulation layer, diffuse into the communicating passages and are returned to the accelerator vacuum chamber. The invention allows the continuous removal of deuterons from the target in conventional water cooled neutron generating apparatus. Preferably, the target is provided with thin barrier layers to prevent undesirable tritium diffusion out of the target layer, as well as deuteron diffusion into the target layer

  16. High performance message passing for the ATLAS DAQ/EF-1 project

    CERN Document Server

    Mornacchi, Giuseppe

    1999-01-01

    Summary form only. A message passing library has been developed in the context of the ATLAS DAQ/EF-1 project. It is used for time critical applications within the front-end part of the DAQ system, mainly to exchange data control messages between I/O processors. Key objectives of the design were low message overheads, efficient use of the data transfer buses, provision of broadcast functionality and a hardware and operating system independent implementation of the application interface. The design and implementation of the message passing library are presented. As required by the project, the implementation is based on commercial components, namely VMEbus, PCI, the Lynx-OS real-time operating system and an additional inter- processor link, PVIC. The latter offers broadcast functionality identified as being important to the overall performance of the message passing. In addition, performance benchmarks for all implementing buses are presented for both simple test programs and the full DAQ applications. (0 refs)...

  17. Convection heat transfer in the double pass solar collector with porous media

    International Nuclear Information System (INIS)

    Md Yusof Theeran; Mohd Yusof Othman; Baharuddin Yatim; Kamaruzzaman Sopian; Mohd Hafidz Roslan

    2006-01-01

    This paper describes about heat transfer characteristics in the double pass solar heater with porous media. Nusselt and Stanton number had been used to shown the heat transfer. Nusselt number had been measured and compared with several theories. Stanton number in the double pass solar heater with porous media and without porous media had been compared. Predicted value of Stanton number will be shown in this paper

  18. Factors influencing immediate post-release survival of spectacled eiders following surgical implantation of transmitters with percutaneous antennae

    Science.gov (United States)

    Sexson, Matthew G.; Mulcahy, Daniel M.; Spriggs, Maria; Myers, Gwen E.

    2014-01-01

    Surgically implanted transmitters are a common method for tracking animal movements. Immediately following surgical implantation, animals pass through a critical recovery phase when behaviors may deviate from normal and the likelihood of individual survival may be reduced. Therefore, data collected during this period may be censored to minimize bias introduced by surgery-related behaviors or mortality. However, immediate post-release mortalities negate a sampling effort and reduce the amount of data potentially collected after the censoring period. Wildlife biologists should employ methods to support an animal’s survival through this period, but factors contributing to immediate post-release survival have not been formally assessed. We evaluated factors that potentially influenced the immediate post-release survival of 56 spectacled eiders (Somateria fischeri) marked with coelomically implanted satellite transmitters with percutaneous antennae in northern Alaska in 2010 and 2011. We modeled survival through the first 14 days following release and assessed the relative importance and effect of 15 covariates hypothesized to influence survival during this immediate post-release period. Estimated daily survival rate increased over the duration of the immediate post-release period; the probability of mortality was greatest within the first 5 days following release. Our top-ranking model included the effect of 2 blood analytes, pH and hematocrit, measured prior to surgical implantation of a transmitter. We found a positive response to pH; eiders exhibiting acidemia (low pH) prior to surgery were less likely to survive the immediate post-release period. We found a curvilinear response to hematocrit; eiders exhibiting extremely low or high pre-surgery hematocrit were also less likely to survive the immediate post-release period. In the interest of maximizing the survival of marked birds following release, hematological data obtained prior to surgical implantation of

  19. The Canal da Piracema at Itaipu Dam as a fish pass system

    Directory of Open Access Journals (Sweden)

    Sérgio Makrakis

    Full Text Available The Canal da Piracema is the longest (nearly 10 km fish pass system in the world. The construction of this fish pass was somehow controversial, because it connected two distinct ichthyofaunistic provinces. This study evaluated the ichthyofauna present in the Canal da Piracema and the abundance and distribution of long-distance migratory fish species along this fish pass system (evaluated possible selectivity. The Canal da Piracema was shown to be difficult to sample because of its environmental heterogeneity: artificial ponds, ladders and nature-like fish pass. To solve this problem, we used several fishing gears, adequate for the several biotopes present (unstructured and structured littoral were sampled with seining nets and electrofishing; lentic were sampled with gillnets and longlines (deeper areas; and rapid water areas were sampled with cast nets. The ichthyofauna of the Canal da Piracema followed the pattern for South America and the Paraná River, with a predominance of Characiformes and Siluriformes. The most representative families were Characidae, Anostomidae, Pimelodidae and Loricariidae. We captured 116 species (17 were long-distance migratory during the period studied. Small-sized species were predominant in unstructured and structured littoral areas, especially Bryconamericus exodon and Apareiodon affinis.The most abundant species was Hypostomus spp. in lentic areas, followed by Iheringichthys labrosus. Hoplias aff. malabaricus predominated in deeper lentic areas. Long-distance migratory species were abundant in rapid waters; they were Prochilodus lineatus and Leporinus elongatus. The sharp reduction in the number of species, including migratory ones, is an indication that the Canal da Piracema is selecting the species that ascend it. Therefore, the search for information on the efficiency of the various fish passes present in the Canal da Piracema is fundamental, to facilitate upward movements of fish. If this is reached, this

  20. Effects of Data Passing Semantics and Operating System Structure on Network I/O Performance

    National Research Council Canada - National Science Library

    Brustoloni, Jose

    1997-01-01

    .... Researchers have often proposed changing the semantics of I/O data passing, so as to make copying unnecessary, or the structure of the operating system, so as to reduce or eliminate data and control passing...

  1. Pulse propagation in a two-pass optical amplifier with arbitrary laser beams overlap

    Directory of Open Access Journals (Sweden)

    AH Farahbod

    2011-09-01

    Full Text Available An analytical model for two-pass optical amplifier with arbitrary beams overlap has been developed which generalized the classical theory of Frantz-Nodvik for single pass amplifier. The effect of counterpropagating beams on gain and output energy fluence included in the model. Moreover, the appropriate limiting relations for two special cases of weak input signal and saturation state of the amplifier gain have been derived. The results indicate that for complete beams overlap, the gain and output energy have the least values. The model predictions are consistent with experimental observations and exact analytical model for two-pass amplifier when beam propagation paths are coincided.

  2. Variation of rolling noise during train pass-bys

    NARCIS (Netherlands)

    Dittrich, M.G.

    2013-01-01

    Railway pass-by noise measurements on different types of tracks sometimes display a significant difference between the rise and decrease in rolling noise at the front and the back of the train. This can potentially have different causes. Whilst this may not necessarily be relevant for the total

  3. 20 CFR 416.2096 - Basic pass-along rules.

    Science.gov (United States)

    2010-04-01

    ... residents of Medicaid facilities where Medicaid pays more than 50 percent of the cost of their care (see..., unless the State furnishes us satisfactory evidence to the contrary. (b) Meeting the pass-along... was in compliance for such preceding 12-month period. The combined Federal/State payment level for...

  4. A calculation technique of passing of a powerful relativistic beam through substance

    International Nuclear Information System (INIS)

    Pobitko, A.I.; Sal'nikov, L.I.; Sukhovitskij, E.Sh.

    1995-01-01

    The calculation algorithm of passing powerful relativistic beam through substance is developed. Algorithm of calculation is separated on the following problems: 1) a trial charge movement in electromagnetic field of the cylindrical geometry; 2) a computing of own electromagnetic field arising at movement of a particle heavy-current beam in a target; 3) accounting of an interaction of a beam with target atoms; 4) accounting of change of the target properties in a time; 5) geometry and construction of an iterative procedure of calculation. The calculation of passing heavy-current beams of charged particles for transient case is carried out by Monte Carlo method. A conclusion of equations of movement trial charge and technique of calculation own electromagnetic field of the powerful relativistic beam at passing through substance are resulted. 6 refs

  5. Message-Passing Receivers for Single Carrier Systems with Frequency-Domain Equalization

    DEFF Research Database (Denmark)

    Zhang, Chuanzong; Manchón, Carles Navarro; Wang, Zhongyong

    2015-01-01

    In this letter, we design iterative receiver algorithms for joint frequency-domain equalization and decoding in a single carrier system assuming perfect channel state information. Based on an approximate inference framework that combines belief propagation (BP) and the mean field (MF) approximation......, we propose two receiver algorithms with, respectively, parallel and sequential message-passing schedules in the MF part. A recently proposed receiver based on generalized approximate message passing (GAMP) is used as a benchmarking reference. The simulation results show that the BP-MF receiver...

  6. Computational Methods to Work as First-Pass Filter in Deleterious SNP Analysis of Alkaptonuria

    Directory of Open Access Journals (Sweden)

    R. Magesh

    2012-01-01

    Full Text Available A major challenge in the analysis of human genetic variation is to distinguish functional from nonfunctional SNPs. Discovering these functional SNPs is one of the main goals of modern genetics and genomics studies. There is a need to effectively and efficiently identify functionally important nsSNPs which may be deleterious or disease causing and to identify their molecular effects. The prediction of phenotype of nsSNPs by computational analysis may provide a good way to explore the function of nsSNPs and its relationship with susceptibility to disease. In this context, we surveyed and compared variation databases along with in silico prediction programs to assess the effects of deleterious functional variants on protein functions. In other respects, we attempted these methods to work as first-pass filter to identify the deleterious substitutions worth pursuing for further experimental research. In this analysis, we used the existing computational methods to explore the mutation-structure-function relationship in HGD gene causing alkaptonuria.

  7. Computational Methods to Work as First-Pass Filter in Deleterious SNP Analysis of Alkaptonuria

    Science.gov (United States)

    Magesh, R.; George Priya Doss, C.

    2012-01-01

    A major challenge in the analysis of human genetic variation is to distinguish functional from nonfunctional SNPs. Discovering these functional SNPs is one of the main goals of modern genetics and genomics studies. There is a need to effectively and efficiently identify functionally important nsSNPs which may be deleterious or disease causing and to identify their molecular effects. The prediction of phenotype of nsSNPs by computational analysis may provide a good way to explore the function of nsSNPs and its relationship with susceptibility to disease. In this context, we surveyed and compared variation databases along with in silico prediction programs to assess the effects of deleterious functional variants on protein functions. In other respects, we attempted these methods to work as first-pass filter to identify the deleterious substitutions worth pursuing for further experimental research. In this analysis, we used the existing computational methods to explore the mutation-structure-function relationship in HGD gene causing alkaptonuria. PMID:22606059

  8. BEHAVIORAL DECISION-THEORY AND ENVIRONMENTAL RISK MANAGEMENT - ASSESSMENT AND RESOLUTION OF 4 SURVIVAL DILEMMAS

    NARCIS (Netherlands)

    VLEK, C; KEREN, G

    Environmental degradation and the call for 'sustainable development' provide an extended context and new challenges for decision-theoretic research on risk assessment and management. We characterize environmental risk management as the resolution of four different types of 'survival' dilemmas in

  9. The effects of the Dutch museum pass on museum visits and museum revenues

    NARCIS (Netherlands)

    van der Werff, S.; Koopmans, C.; Boyer, C.

    2014-01-01

    The Dutch museum pass gives unlimited access for a year to most major Dutch museums and around the half of all Dutch museums for a fixed fee. The fee revenues are distributed among participating museums in proportion to the amount of visits by pass holders and their ticket prices. In this paper, it

  10. Climatic variation and age-specific survival in Asian elephants from Myanmar.

    Science.gov (United States)

    Mumby, Hannah S; Courtiol, Alexandre; Mar, Khyne U; Lummaa, Virpi

    2013-05-01

    conditions within average years doubled the odds for mortality. The persistence of a long-term trend toward higher global temperatures, combined with the possibility of higher variation in temperature between seasons, may pose a challenge to the survival of species such as Asian elephants.

  11. A Privacy-Preserving NFC Mobile Pass for Transport Systems

    Directory of Open Access Journals (Sweden)

    Ghada Arfaoui

    2014-12-01

    Full Text Available The emergence of the NFC (Near Field Communication technology brings new capacities to the next generation of smartphones, but also new security and privacy challenges. Indeed through its contactless interactions with external entities, the smartphone of an individual will become an essential authentication tool for service providers such as transport operators. However, from the point of view of the user, carrying a part of the service through his smartphone could be a threat for his privacy. Indeed, an external attacker or the service provider himself could be tempted to track the actions of the user. In this paper, we propose a privacy-preserving contactless mobile service, in which a user’s identity cannot be linked to his actions when using the transport system. The security of our proposition relies on the combination of a secure element in the smartphone and on a privacy-enhancing cryptographic protocol based on a variant of group signatures. In addition, although a user should remain anonymous and his actions unlinkable in his daily journeys, we designed a technique for lifting his anonymity in extreme circumstances. In order to guarantee the usability of our solution, we implemented a prototype demonstrating that our solution meets the major functional requirements for real transport systems: namely that the mobile pass can be validated at a gate in less than 300 ms, and this even if the battery of the smartphone is exhausted.

  12. Compensatory effects of recruitment and survival when amphibian populations are perturbed by disease

    Science.gov (United States)

    Muths, E.; Scherer, R. D.; Pilliod, D.S.

    2011-01-01

    The need to increase our understanding of factors that regulate animal population dynamics has been catalysed by recent, observed declines in wildlife populations worldwide. Reliable estimates of demographic parameters are critical for addressing basic and applied ecological questions and understanding the response of parameters to perturbations (e.g. disease, habitat loss, climate change). However, to fully assess the impact of perturbation on population dynamics, all parameters contributing to the response of the target population must be estimated. We applied the reverse-time model of Pradel in Program mark to 6years of capture-recapture data from two populations of Anaxyrus boreas (boreal toad) populations, one with disease and one without. We then assessed a priori hypotheses about differences in survival and recruitment relative to local environmental conditions and the presence of disease. We further explored the relative contribution of survival probability and recruitment rate to population growth and investigated how shifts in these parameters can alter population dynamics when a population is perturbed. High recruitment rates (0??41) are probably compensating for low survival probability (range 0??51-0??54) in the population challenged by an emerging pathogen, resulting in a relatively slow rate of decline. In contrast, the population with no evidence of disease had high survival probability (range 0??75-0??78) but lower recruitment rates (0??25). Synthesis and applications.We suggest that the relationship between survival and recruitment may be compensatory, providing evidence that populations challenged with disease are not necessarily doomed to extinction. A better understanding of these interactions may help to explain, and be used to predict, population regulation and persistence for wildlife threatened with disease. Further, reliable estimates of population parameters such as recruitment and survival can guide the formulation and implementation of

  13. 9 CFR 315.2 - Carcasses and parts passed for cooking; utilization for food purposes after cooking.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses and parts passed for cooking; utilization for food purposes after cooking. 315.2 Section 315.2 Animals and Animal Products FOOD SAFETY AND... PARTS PASSED FOR COOKING § 315.2 Carcasses and parts passed for cooking; utilization for food purposes...

  14. Comparing NET and ERI standardized exam scores between baccalaureate graduates who pass or fail the NCLEX-RN.

    Science.gov (United States)

    Bondmass, Mary D; Moonie, Sheniz; Kowalski, Susan

    2008-01-01

    In the United States, nursing programs are commonly evaluated by their graduates success on the National Council Licensure Examination for Registered Nurses (NCLEX-RN). The purpose of this paper is to describe a change in NCLEX-RN success rates following the addition of standardized exams throughout our program's curriculum, and to compare these exam scores between graduates who pass NCLEX-RN and those who do not. Our results indicate an 8.5% change (p pass rate from our previous 5-year mean pass rate, and significant differences in standardized test scores for those who pass the NCLEX-RN compared to those who do not (p pass NCLEX-RN than not.

  15. Leaning and Greening the Supply Chain: A Teaching Case Study for Engineering Students

    Science.gov (United States)

    Grantham, Katie; Cudney, Elizabeth

    2011-01-01

    A version of the American Clean Energy and Security Act, passed by the House of Representatives in June 2009, mandates a 17% cut in emissions by 2020 and upwards of an 80% cut by 2050, based on emissions from 2005. This impending legislation is a challenge to companies already trying to survive in an economic downturn. It is critical that the…

  16. Costs of an immune challenge and terminal investment in a long-lived bird.

    Science.gov (United States)

    Hanssen, Sveinn Are

    2006-10-01

    An induced immune challenge can have two counteracting effects on an individual's reproductive investment. (1) The resource demand could increase to "fuel" the immunologic reaction, which in turn can lead to an adaptive decrease in investment in resource-costly activities, such as reproduction. One the other hand, (2) the individual could assume that the immune activity it experiences is indicative of a serious infection. The latter can lead to an adaptive increase in reproductive investment in response to the reduced prospects of survival and future reproduction, so called "terminal investment." To measure such life-history-related consequences of increased immune activity, one group of incubating female Common Eiders (Somateria mollissima) was injected with a nonpathogenic antigen (sheep red blood cells, SRBC) while controls were injected with sterile saline. The eider is a long-lived sea-duck. Females, who incubate the eggs and care for young without assistance from the male, engage in facultative anorexia during incubation leading to a large reduction in body mass. Eiders can abandon their young to other females at the cost of reduced young survival. The immune challenge resulted in a larger mass loss, a prolonged incubation period, and reduced return rate, demonstrating both short- and long-term costs of immune challenge. Additionally, in response to what might have been interpreted as reduced survival chances in immune-challenged females, these females more often tended their own brood after hatching, despite having suffered higher costs during incubation.

  17. O fim do passe e as transferências de jogadores Brasileiros em uma época de globalização The end of the passe and the transfer of Brazilian players in an era of globalization

    Directory of Open Access Journals (Sweden)

    Francisco Xavier Freire Rodrigues

    2010-08-01

    Full Text Available O artigo aborda as recentes transformações na legislação futebolística brasileira e seus impactos no mercado de trabalho. Analisa a influência do fim do passe nas transferências (internas e externas de jogadores de futebol no Brasil. Trata-se de uma investigação empírica, o fim do passe e a exportação de jogadores brasileiros. Utilizamos técnicas de pesquisa quantitativas e qualitativas (questionários e entrevistas. Aplicamos 97 questionários com atletas de 12 clubes do campeonato brasileiro de futebol das Séries A, B e C. A pesquisa indica que o fim do passe criou novas condições para as transferências internas e externas de jogadores brasileiros. Houve crescimento significativo das transferências internacionais de jogadores depois do fim do passe, acentuando a exportação de atletas brasileiros. Além da globalização, as razões desse crescimento devem-se ao fato de que a Lei Pelé facilitou as transferências ao decretar o fim do passe, estabelecer a liberdade de trabalho e flexibilizar os contratos.The article discusses the recent changes in the Brazilian sports legislation and its impact on the labor market. It analyzes the influence of the end of the passe in (internal and external transfers of football players in Brazil. This is an empirical investigation of the end of the passe and the export of Brazilian players. It makes use of quantitative and qualitative research techniques (questionnaires and interviews. The author applied 97 questionnaires to athletes from 12 clubs of the Brazilian football championship series A, B and C. The research indicates that the end of the passe has created new conditions for internal and external transfers of Brazilian players. There was a significant increase in the number of international transfers of players after the end of the passe, expanding the export of Brazilian athletes. In addition to the globalization, the reasons for this increase are due to the fact that the Pelé Law

  18. Enhancing the child survival agenda to promote, protect, and support early child development.

    Science.gov (United States)

    Jensen, Sarah K G; Bouhouch, Raschida R; Walson, Judd L; Daelmans, Bernadette; Bahl, Rajiv; Darmstadt, Gary L; Dua, Tarun

    2015-08-01

    High rates of child mortality and lost developmental potential in children under 5 years of age remain important challenges and drivers of inequity in the developing world. Substantive progress has been made toward Millennium Development Goal (MDG) 4 to improve child survival, but as we move into the post-2015 sustainable development agenda, much more work is needed to ensure that all children can realize their full and holistic physical, cognitive, psychological, and socio-emotional development potential. This article presents child survival and development as a continuous and multifaceted process and suggests that a life-course perspective of child development should be at the core of future policy making, programming, and research. We suggest that increased attention to child development, beyond child survival, is key to operationalize the sustainable development goals (SDGs), address inequities, build on the demographic dividend, and maximize gains in human potential. An important step toward implementation will be to increase integration of existing interventions for child survival and child development. Integrated interventions have numerous potential benefits, including optimization of resource use, potential additive impacts across multiple domains of health and development, and opportunity to realize a more holistic approach to client-centered care. However, a notable challenge to integration is the continued division between the health sector and other sectors that support child development. Despite these barriers, empirical evidence is available to suggest that successful multisectoral coordination is feasible and leads to improved short- and long-term outcomes in human, social, and economic development. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. A second chance at life: people's lived experiences of surviving out-of-hospital cardiac arrest.

    Science.gov (United States)

    Forslund, Ann-Sofie; Jansson, Jan-Håkan; Lundblad, Dan; Söderberg, Siv

    2017-12-01

    There is more to illuminate about people's experiences of surviving out-of-hospital cardiac arrest (OHCA) and how such an event affects people's lives over time. This study aimed to elucidate meanings of people's lived experiences and changes in everyday life during their first year after surviving OHCA. A qualitative, longitudinal design was used. Eleven people surviving OHCA from northern Sweden agreed to participate and were interviewed 6 and 12 months after the event. A phenomenological hermeneutic interpretation was used to analyse the transcribed texts. The structural analysis resulted in two themes: (i) striving to regain one's usual self and (ii) a second chance at life, and subthemes (ia) testing the body, (ib) pursuing the ordinary life, (ic) gratitude for help to survival, (iia) regaining a sense of security with one's body, (iib) getting to know a new self, and (iic) seeking meaning and establishing a future. To conclude, we suggest that people experienced meanings of surviving OHCA over time as striving to regain their usual self and getting a second chance at life. The event affected them in many ways and resulted in a lot of emotions and many things to think about. Participants experienced back-and-forth emotions, when comparing their present lives to both their lives before cardiac arrest and those lives they planned for the future. During their first year, participants' daily lives were still influenced by 'being dead' and returning to life. As time passed, they wanted to resume their ordinary lives and hoped for continued lives filled with meaning and joyous activities. © 2017 Nordic College of Caring Science.

  20. Testing the Turing Test — do Men Pass It?

    Science.gov (United States)

    Adam, Ruth; Hershberg, Uri; Schul, Yaacov; Solomon, Sorin

    We are fascinated by the idea of giving life to the inanimate. The fields of Artificial Life and Artificial Intelligence (AI) attempt to use a scientific approach to pursue this desire. The first steps on this approach hark back to Turing and his suggestion of an imitation game as an alternative answer to the question "can machines think?".1 To test his hypothesis, Turing formulated the Turing test1 to detect human behavior in computers. But how do humans pass such a test? What would you say if you would learn that they do not pass it well? What would it mean for our understanding of human behavior? What would it mean for our design of tests of the success of artificial life? We report below an experiment in which men consistently failed the Turing test.

  1. Research on optimizing pass schedule of tandem cold mill

    International Nuclear Information System (INIS)

    Lu, C.; Wang, J.S.; Zhao, Q.L.; Liu, X.H.; Wang, G.D.

    2000-01-01

    In this paper, research on pass schedule of tandem cold mill (TCM) is carried out. According to load (reduction, rolling force, motor power) balance, non-linear equations set with variables of inter-stand thickness is constructed. The pass schedule optimization is carried out by solving the non-linear equations set. As the traditional method, the Newton-Raphson method is used for solving the non-linear equations set. In this paper a new simple method is brought up. On basis of the monotone relations between thickness and load, the inter-stands thickness is adjusted dynamically. The solution of non-linear equations set can be converged by iterative calculation. This method can avoid the derivative calculation used by traditional method. So, this method is simple and calculation speed is high. It is suitable for on-line control. (author)

  2. A Dynamic Continuation-Passing Style for Dynamic Delimited Continuations

    DEFF Research Database (Denmark)

    Biernacki, Dariusz; Danvy, Olivier; Millikin, Kevin Scott

    2005-01-01

    We present a new abstract machine that accounts for dynamic delimited continuations. We prove the correctness of this new abstract machine with respect to a pre-existing, definitional abstract machine. Unlike this definitional abstract machine, the new abstract machine is in defunctionalized form......, which makes it possible to state the corresponding higher-order evaluator. This evaluator is in continuation+state passing style and threads a trail of delimited continuations and a meta-continuation. Since this style accounts for dynamic delimited continuations, we refer to it as `dynamic continuation......-passing style.' We show that the new machine operates more efficiently than the definitional one and that the notion of computation induced by the corresponding evaluator takes the form of a monad. We also present new examples and a new simulation of dynamic delimited continuations in terms of static ones....

  3. Statistical Requirements For Pass-Fail Testing Of Contraband Detection Systems

    International Nuclear Information System (INIS)

    Gilliam, David M.

    2011-01-01

    Contraband detection systems for homeland security applications are typically tested for probability of detection (PD) and probability of false alarm (PFA) using pass-fail testing protocols. Test protocols usually require specified values for PD and PFA to be demonstrated at a specified level of statistical confidence CL. Based on a recent more theoretical treatment of this subject [1], this summary reviews the definition of CL and provides formulas and spreadsheet functions for constructing tables of general test requirements and for determining the minimum number of tests required. The formulas and tables in this article may be generally applied to many other applications of pass-fail testing, in addition to testing of contraband detection systems.

  4. Axioms for behavioural congruence of single-pass instruction sequences

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2017-01-01

    In program algebra, an algebraic theory of single-pass instruction sequences, three congruences on instruction sequences are paid attention to: instruction sequence congruence, structural congruence, and behavioural congruence. Sound and complete axiom systems for the first two congruences were

  5. RADICAL INNOVATION AND EARLY STAGE FINANCING GAPS: EQUITY-BASED CROWDFUNDING CHALLENGES

    OpenAIRE

    Deffains-Crapsky, Catherine; Sudolska, Agata

    2014-01-01

    Innovations and innovativeness in a business context is considered as one of the key determinants of competitive advantage due to its productive role in driving new markets and revenue growth as well as other value propositions. The success of this economic transition will pass by a context favorable to the innovation in general and to the entrepreneurial innovation in particular. Earlystage start-ups financing face particular difficulties. We focus on current challenges concerning entreprene...

  6. Incremental first pass technique to measure left ventricular ejection fraction

    International Nuclear Information System (INIS)

    Kocak, R.; Gulliford, P.; Hoggard, C.; Critchley, M.

    1980-01-01

    An incremental first pass technique was devised to assess the acute effects of any drug on left ventricular ejection fraction (LVEF) with or without a physiological stress. In particular, the effects of the vasodilater isosorbide dinitrate on LVEF before and after exercise were studied in 11 patients who had suffered cardiac failure. This was achieved by recording the passage of sup(99m)Tc pertechnetate through the heart at each stage of the study using a gamma camera computer system. Consistent values for four consecutive first pass values without exercise or drug in normal subjects illustrated the reproducibility of the technique. There was no significant difference between LVEF values obtained at rest and exercise before or after oral isosorbide dinitrate with the exception of one patient with gross mitral regurgitation. The advantages of the incremental first pass technique are that the patient need not be in sinus rhythm, the effects of physiological intervention may be studied and tests may also be repeated at various intervals during long term follow-up of patients. A disadvantage of the method is the limitation in the number of sequential measurements which can be carried out due to the amount of radioactivity injected. (U.K.)

  7. Per-beam, planar IMRT QA passing rates do not predict clinically relevant patient dose errors

    International Nuclear Information System (INIS)

    Nelms, Benjamin E.; Zhen Heming; Tome, Wolfgang A.

    2011-01-01

    Purpose: The purpose of this work is to determine the statistical correlation between per-beam, planar IMRT QA passing rates and several clinically relevant, anatomy-based dose errors for per-patient IMRT QA. The intent is to assess the predictive power of a common conventional IMRT QA performance metric, the Gamma passing rate per beam. Methods: Ninety-six unique data sets were created by inducing four types of dose errors in 24 clinical head and neck IMRT plans, each planned with 6 MV Varian 120-leaf MLC linear accelerators using a commercial treatment planning system and step-and-shoot delivery. The error-free beams/plans were used as ''simulated measurements'' (for generating the IMRT QA dose planes and the anatomy dose metrics) to compare to the corresponding data calculated by the error-induced plans. The degree of the induced errors was tuned to mimic IMRT QA passing rates that are commonly achieved using conventional methods. Results: Analysis of clinical metrics (parotid mean doses, spinal cord max and D1cc, CTV D95, and larynx mean) vs IMRT QA Gamma analysis (3%/3 mm, 2/2, 1/1) showed that in all cases, there were only weak to moderate correlations (range of Pearson's r-values: -0.295 to 0.653). Moreover, the moderate correlations actually had positive Pearson's r-values (i.e., clinically relevant metric differences increased with increasing IMRT QA passing rate), indicating that some of the largest anatomy-based dose differences occurred in the cases of high IMRT QA passing rates, which may be called ''false negatives.'' The results also show numerous instances of false positives or cases where low IMRT QA passing rates do not imply large errors in anatomy dose metrics. In none of the cases was there correlation consistent with high predictive power of planar IMRT passing rates, i.e., in none of the cases did high IMRT QA Gamma passing rates predict low errors in anatomy dose metrics or vice versa. Conclusions: There is a lack of correlation between

  8. Note Passing and Gendered Discipline in Vietnamese Schools

    Science.gov (United States)

    Horton, Paul

    2015-01-01

    While researchers agree that note passing is predominantly an activity engaged in by girls, there has been relatively little consideration of why this is the case. In this article, I argue that gendered expectations about the appropriate characters of boys and girls in Vietnam are incorporated into the disciplinary framework of schools, and that…

  9. Plants profile of Malakand Pass Hills, District Malakand, Pakistan

    African Journals Online (AJOL)

    use

    2011-11-21

    Nov 21, 2011 ... famous Malakand fort guards the road on both sides of the pass. Malakand is a ... Underneath Malakand Hills, the waters of the River Swat ... southern sloping faces of the hills. They speak ...... Pinus roxburghii Sarg. Antidote ...

  10. Notational analysis on tactical passing skills used by collegiate ...

    African Journals Online (AJOL)

    Notational analysis on tactical passing skills used by collegiate players in an indoor hockey masum tournament. K.N. Hasnor, H Hizan, M.I. Shahril, N.A. Kosni, M.R. Abdullah, A.B.H.M. Maliki, S.M. Mat-Rasid ...

  11. 3D characterization of a Great Basin geothermal system: Astor Pass, NV

    Science.gov (United States)

    Siler, D. L.; Mayhew, B.; Faulds, J. E.

    2012-12-01

    The Great Basin exhibits both anomalously high heat flow (~75±5 mWm-2) and active faulting and extension resulting in robust geothermal activity. There are ~430 known geothermal systems in the Great Basin, with evidence suggesting that undiscovered blind geothermal systems may actually represent the majority of geothermal activity. These systems employ discrete fault intersection/interaction areas as conduits for geothermal circulation. Recent studies show that steeply dipping normal faults with step-overs, fault intersections, accommodation zones, horse-tailing fault terminations and transtensional pull-aparts are the most prominent structural controls of Great Basin geothermal systems. These fault geometries produce sub-vertical zones of high fault and fracture density that act as fluid flow conduits. Structurally controlled fluid flow conduits are further enhanced when critically stressed with respect to the ambient stress conditions. The Astor Pass blind geothermal system, northwestern Nevada, lies along the boundary between the Basin and Range to the east and the Walker Lane to the west. Along this boundary, strain is transferred from dextral shear in the Walker Lane to west-northwest directed extension in the Basin and Range. As such, the Astor Pass area lies in a transtensional setting consisting of both northwest-striking, left-stepping dextral faults and more northerly striking normal faults. The Astor Pass tufa tower implies the presence of a blind geothermal system. Previous studies suggest that deposition of the Astor Pass tufa was controlled by the intersection of a northwest-striking dextral normal fault and north-northwest striking normal fault. Subsequent drilling (to ~1200 m) has revealed fluid temperatures of ~94°C, confirming the presence of a blind geothermal system at Astor Pass. Expanding upon previous work and employing additional detailed geologic mapping, interpretation of 2D seismic reflection data and analysis of well cuttings, a 3

  12. Experimental study of boundary-layer transition on an airfoil induced by periodically passing wake

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, W.P. [Center for Turbulence and Flow Control Research Institute of Advanced Machinery and Design, Seoul National University (Korea); Park, T.C.; Kang, S.H. [School of Mechanical and Aerospace Engineering, Seoul National University (Korea)

    2002-02-01

    Hot-wire measurements are performed in boundary-layer flows developing on a NACA 0012 airfoil over which wakes pass periodically. The periodic wakes are generated by rotating circular cylinders clockwise or counterclockwise around the airfoil. The time- and phase-averaged mean streamwise velocities and turbulence fluctuations are measured to investigate the phenomena of wake-induced transition. Especially, the phase-averaged wall shear stresses are evaluated using a computational Preston tube method. The passing wakes significantly change the pressure distribution on the airfoil, which has influence on the transition process of the boundary layer. The orientation of the passing wake alters the pressure distribution in a different manner. Due to the passing wake, the turbulent patches are generated inside the laminar boundary layer on the airfoil, and the boundary layer becomes temporarily transitional. The patches propagate downstream at a speed smaller than the free-stream velocity and merge together further downstream. Relatively high values of phase-averaged turbulence fluctuations in the outer part of the boundary layer indicate the possibility that breakdown occurs in the outer layer away from the wall. It is confirmed that the phase-averaged mean velocity profile has two dips in the outer region of the transitional boundary layer for each passing cycle. (orig.)

  13. Single Pass Albumin Dialysis in Hepatorenal Syndrome

    Directory of Open Access Journals (Sweden)

    Rahman Ebadur

    2008-01-01

    Full Text Available Hepatorenal syndrome (HRS is the most appalling complication of acute or chronic liver disease with 90% mortality rate. Single pass albumin dialysis (SPAD can be considered as a noble liver support technique in HRS. Here, we present a case of a young healthy patient who developed hyperacute fulminant liver failure that progressed to HRS. The patient was offered SPAD as a bridge to liver transplantation, however, it resulted in an excellent recovery.

  14. A population study of golden eagles in the Altamont Pass Wind Resource area. Second-year progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    Since January 1994, the Predatory Bird Research Group, University of California, Santa Cruz, has been conducting a field investigation of the ecology of golden eagles (Aquila chrysaetos) in the vicinity of the Altamont Pass Wind Resource Area (WRA). The 190 km{sup 2} facility lies just east of San Francisco Bay in California and contains about 6,500 wind turbines. Grassland and oak savanna habitats surrounding the WRA support a substantial resident population of golden eagles. Each year, the U.S. Fish and Wildlife Service receivers reports from the wind industry of about 30 golden eagle casualties occurring at the WRA, and it is probable that many more carcasses go unnoticed. Over 90 percent of the casualties are attributed to collisions with wind turbines. The main purpose of this study is to estimate the effect of turbine-related mortality on the golden eagle population of the area. Assessing the impact of the WRA kills on the population requires quantification of both survival and reproduction. To estimate survival rates of both territorial and non-territorial golden eagles, we tagged 179 individuals with radio-telemetry transmitters expected to function for about four years and equipped with mortality sensors. Population segments represented in the tagged sample include 79 juveniles, 45 subadults, 17n floaters (non-territorial adults), and 38 breeders. Effective sample sizes in the older segments increase as younger eagles mature or become territorial. Since the beginning of the study, we have conducted weekly roll-call surveys by airplane to locate the tagged eagles in relation to the WRA and to monitor their survival. The surveyed area extends from the Oakland Hills southeast through the Diablo Mountain Range to San Luis Reservoir about 75 km southeast of the WRA. The surveys show that breeding eagles rarely enter the WRA while the non-territorial eagles tend to move about freely throughout the study area and often visit the WRA.

  15. Assessment of PASS Effectiveness under Severe Accidents in Nuclear Power Plants

    International Nuclear Information System (INIS)

    Choi, Yu Jung; Lee, Sung Bok; Kim, Hyeong Taek; Lee, Jin Yong

    2008-01-01

    Following the accident at Three Mile Island Unit 2 (TMI-2) on March 28, 1979, the USNRC formed a lessons-learned Task Force to identify and evaluate safety concerns originating with the TMI-2 accident. NUREG-0578 documented the results of the task force effort. One of the recommendations of the task force was for licensees to upgrade the capability to obtain samples from the reactor coolant system and containment atmosphere under high radioactivity conditions and to provide the capability for chemical and spectral analyses of high-level samples on site. NUREG-0737 contained the details of the TMI recommendations that were to be implemented by the licensees. Additional criteria for post accident sampling system(PASS) were issued by Regulatory Guide 1.97. As the results, PASS has been installed on nuclear power plants(NPPs) in Korea as well as United States. However, significant improvements have been achieved since the TMI-2 accident in the areas of understanding risks associated with nuclear plant operations and developing better strategies for managing the response to potential severe accidents at NPPs. Thus, the requirements for PASS have been re-evaluated in some reports. According to the reports, the samples and measurements from PASS do not contribute significantly to emergency management response to severe accidents due to the long analyzing time, 3 hours. Hence, this paper focused on the development of the quantitative analysis methodology to analyze the sequence of the severe accident in Yonggwang nuclear power plants (YGN) and presented the results of the analysis according to the developed methodology

  16. Bronchus-associated lymphoid tissue (BALT and survival in a vaccine mouse model of tularemia.

    Directory of Open Access Journals (Sweden)

    Damiana Chiavolini

    2010-06-01

    Full Text Available Francisella tularensis causes severe pulmonary disease, and nasal vaccination could be the ideal measure to effectively prevent it. Nevertheless, the efficacy of this type of vaccine is influenced by the lack of an effective mucosal adjuvant.Mice were immunized via the nasal route with lipopolysaccharide isolated from F. tularensis and neisserial recombinant PorB as an adjuvant candidate. Then, mice were challenged via the same route with the F. tularensis attenuated live vaccine strain (LVS. Mouse survival and analysis of a number of immune parameters were conducted following intranasal challenge. Vaccination induced a systemic antibody response and 70% of mice were protected from challenge as showed by their improved survival and weight regain. Lungs from mice recovering from infection presented prominent lymphoid aggregates in peribronchial and perivascular areas, consistent with the location of bronchus-associated lymphoid tissue (BALT. BALT areas contained proliferating B and T cells, germinal centers, T cell infiltrates, dendritic cells (DCs. We also observed local production of antibody generating cells and homeostatic chemokines in BALT areas.These data indicate that PorB might be an optimal adjuvant candidate for improving the protective effect of F. tularensis antigens. The presence of BALT induced after intranasal challenge in vaccinated mice might play a role in regulation of local immunity and long-term protection, but more work is needed to elucidate mechanisms that lead to its formation.

  17. Microbial survival strategies in ancient permafrost: insights from metagenomics.

    Science.gov (United States)

    Mackelprang, Rachel; Burkert, Alexander; Haw, Monica; Mahendrarajah, Tara; Conaway, Christopher H; Douglas, Thomas A; Waldrop, Mark P

    2017-10-01

    In permafrost (perennially frozen ground) microbes survive oligotrophic conditions, sub-zero temperatures, low water availability and high salinity over millennia. Viable life exists in permafrost tens of thousands of years old but we know little about the metabolic and physiological adaptations to the challenges presented by life in frozen ground over geologic time. In this study we asked whether increasing age and the associated stressors drive adaptive changes in community composition and function. We conducted deep metagenomic and 16 S rRNA gene sequencing across a Pleistocene permafrost chronosequence from 19 000 to 33 000 years before present (kyr). We found that age markedly affected community composition and reduced diversity. Reconstruction of paleovegetation from metagenomic sequence suggests vegetation differences in the paleo record are not responsible for shifts in community composition and function. Rather, we observed shifts consistent with long-term survival strategies in extreme cryogenic environments. These include increased reliance on scavenging detrital biomass, horizontal gene transfer, chemotaxis, dormancy, environmental sensing and stress response. Our results identify traits that may enable survival in ancient cryoenvironments with no influx of energy or new materials.

  18. The PASS project architectural model

    International Nuclear Information System (INIS)

    Day, C.T.; Loken, S.; Macfarlane, J.F.

    1994-01-01

    The PASS project has as its goal the implementation of solutions to the foreseen data access problems of the next generation of scientific experiments. The architectural model results from an evaluation of the operational and technical requirements and is described in terms of an abstract reference model, an implementation model and a discussion of some design aspects. The abstract reference model describes a system that matches the requirements in terms of its components and the mechanisms by which they communicate, but does not discuss policy or design issues that would be necessary to match the model to an actual implementation. Some of these issues are discussed, but more detailed design and simulation work will be necessary before choices can be made

  19. Real-time digital signal recovery for a multi-pole low-pass transfer function system.

    Science.gov (United States)

    Lee, Jhinhwan

    2017-08-01

    In order to solve the problems of waveform distortion and signal delay by many physical and electrical systems with multi-pole linear low-pass transfer characteristics, a simple digital-signal-processing (DSP)-based method of real-time recovery of the original source waveform from the distorted output waveform is proposed. A mathematical analysis on the convolution kernel representation of the single-pole low-pass transfer function shows that the original source waveform can be accurately recovered in real time using a particular moving average algorithm applied on the input stream of the distorted waveform, which can also significantly reduce the overall delay time constant. This method is generalized for multi-pole low-pass systems and has noise characteristics of the inverse of the low-pass filter characteristics. This method can be applied to most sensors and amplifiers operating close to their frequency response limits to improve the overall performance of data acquisition systems and digital feedback control systems.

  20. Meeting forest restoration challenges: Using the Target Plant Concept

    Science.gov (United States)

    Kas Dumroese; Thomas D. Landis; Jeremy Pinto; Diane L. Haase; Kim W. Wilkinson; Anthony S. Davis

    2016-01-01

    Meeting forest restoration challenges relies on successful establishment of plant materials (e.g., seeds, cuttings, rooted cuttings, or seedlings, etc.; hereafter simply "seedlings"). The Target Plant Concept (TPC) provides a flexible framework that nursery managers and their clients can use to improve the survival and growth of these seedlings. The...

  1. Ultra-compact broadband higher order-mode pass filter fabricated in a silicon waveguide for multimode photonics

    DEFF Research Database (Denmark)

    Guan, Xiaowei; Ding, Yunhong; Frandsen, Lars Hagedorn

    2015-01-01

    An ultra-compact and broadband higher order-mode pass filter in a 1D photonic crystal silicon waveguide is proposed and experimentally demonstrated. The photonic crystal is designed for the lower order mode to work in the photonic band gap, while the higher order mode is located in the air band....... Consequently, light on the lower order mode is prohibited to pass through the filter, while light on a higher order mode can be converted to a Bloch mode in the photonic crystal and pass through the filter with low insertion loss. As an example, we fabricate a similar to 15-mu m-long first-order-mode pass...

  2. Environmental conditions shape the temporal pattern of investment in reproduction and survival.

    Science.gov (United States)

    Marasco, Valeria; Boner, Winnie; Griffiths, Kate; Heidinger, Britt; Monaghan, Pat

    2018-01-10

    The relationship between environmental stress exposure and ageing is likely to vary with stressor severity, life-history stage and the time scale over which effects are measured. Such factors could influence whether stress exposure accelerates or slows the ageing process, but their interactions have not previously been experimentally investigated. We found that experimental exposure of zebra finches to mildly challenging environmental circumstances from young to old adulthood, which increased exposure to stress hormones, reduced breeding performance during early adulthood, but had positive effects when individuals were bred in old adulthood. This difference was not due to selective mortality, because the effects were evident within individuals, and no evidence of habituation in the response to the stressor was found. The more stressful environment had no effects on survival during young or old adulthood, but substantially improved survival during middle age. Changes in the effects at different ages could be due to the duration and nature of the challenging exposure, or to variation in coping capacity or strategy with age. These results show that living under challenging environmental circumstances can influence ageing trajectories in terms of both reproductive performance and longevity. Our results provide experimental support for the emerging idea that stress exposure needs to be optimized rather than minimized to obtain the best health outcomes. © 2018 The Author(s).

  3. How to survive in research: advice for the novice investigator.

    Science.gov (United States)

    Siskind, Dan; Parker, Stephen; Loi, Samantha; Looi, Jeffrey C; Macfarlane, Matthew D; Merry, Sally; Smith, Geoff; Kisely, Steve

    2015-02-01

    This paper, written by the RANZCP Committee for Research, provides an outline for how to survive in research, considering the ingredients likely to contribute to success, the role of supportive structures and the expected challenges. Learning how to survive in research is relevant for both trainees and for Fellows undertaking research at any stage of their career. Intellectual curiosity, perseverance, frustration tolerance, patience and humility are key for success as a researcher. Selection of the right supervisor is important, as is development and maintenance of a good working supervisor/supervisee relationship. The personal benefits of undertaking research include flexibility in work hours, and improved skills in writing, oral presentations, objectivity, critical thinking, problem solving and project management. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  4. Decision-aids for enhancing intergovernmental interactions: The Pre-notification Analysis Support System (PASS)

    International Nuclear Information System (INIS)

    Lester, M.; Liebow, E.; Holm, J.

    1994-05-01

    The Department of Energy (DOE) plans to honor its commitment to government-to-government interactions by providing advance notice of DOE spent fuel and high-level waste shipments to Indian tribes whose jurisdictions are crossed by or adjacent to transportation routes. The tribes are important contributors to a regional response network, and providing tribes with advance notice of DOE shipping plans marks the start -- not the end -- of direct, government-to-government interactions with DOE. The Tribal Prenotification Analysis Support System (PASS) is being developed for the Office of Special Programs within the Department's Office of Environmental Restoration and Waste Management. PASS will help DOE-Headquarters to coordinate field office activities and provide technical and institutional support to the DOE field offices. PASS is designed to be used by anyone with minimum computer literacy and having contemporary computer hardware and software. It uses on-screen maps to choose and display a shipment route, and to display the tribal jurisdictions. With forms that are easy to understand, it provides information about each jurisdiction and points of contact. PASS records all contacts, commitments made, and actions taken

  5. Determine the Influence of Time Held in “Knockdown” Anesthesia on Survival and Stress of Surgically Implanted Juvenile Salmonids

    Energy Technology Data Exchange (ETDEWEB)

    Woodley, Christa M.; Wagner, Katie A.; Knox, Kasey M.

    2012-01-31

    The Juvenile Salmon Acoustic Telemetry System (JSATS) was developed for the U.S. Army Corp of Engineers Portland District (USACE) to address questions related to survival and performance measures of juvenile salmonids as they pass through the Federal Columbia River Power System (FCRPS). Researchers using JSATS acoustic transmitters (ATs) were tasked with standardizing the surgical implantation procedure to ensure that the stressors of handling and surgery on salmonids were consistent and less likely to cause effects of tagging in survival studies. Researchers questioned whether the exposure time in 'knockdown' anesthesia (or induction) to prepare fish for surgery could influence the survival of study fish (CBSPSC 2011). Currently, fish are held in knockdown anesthesia after they reach Stage 4 anesthesia until the completion of the surgical implantation of a transmitter, varies from 5 to 15 minutes for studies conducted in the Columbia Basin. The Columbia Basin Surgical Protocol Steering Committee (CBSPSC ) expressed concern that its currently recommended 10-minute maximum time limit during which fish are held in anesthetic - tricaine methanesulfonate (MS-222, 80 mg L-1 water) - could increase behavioral and physiological costs, and/or decrease survival of outmigrating juvenile salmonids. In addition, the variability in the time fish are held at Stage 4 could affect the data intended for direct comparison of fish within or among survival studies. Under the current recommended protocol, if fish exceed the 10-minute time limit, they are to be released without surgical implantation, thereby increasing the number of fish handled and endangered species 'take' at the bypass systems for FCRPS survival studies.

  6. Using Concurrent Cardiovascular Information to Augment Survival Time Data from Orthostatic Tilt Tests

    Science.gov (United States)

    Feiveson, Alan H.; Fiedler, James; Lee, Stuart M. M.; Westby, Christian M.; Stenger, Michael B.; Platts, Steven H.

    2014-01-01

    Orthostatic Intolerance (OI) is the propensity to develop symptoms of fainting during upright standing. OI is associated with changes in heart rate, blood pressure and other measures of cardiac function. Problem: NASA astronauts have shown increased susceptibility to OI on return from space missions. Current methods for counteracting OI in astronauts include fluid loading and the use of compression garments. Multivariate trajectory spread is greater as OI increases. Pairwise comparisons at the same time within subjects allows incorporation of pass/fail outcomes. Path length, convex hull area, and covariance matrix determinant do well as statistics to summarize this spread Missing data problems Time series analysis need many more time points per OTT session treatment of trend? how incorporate survival information?

  7. Band-pass filtering algorithms for adaptive control of compressor pre-stall modes in aircraft gas-turbine engine

    Science.gov (United States)

    Kuznetsova, T. A.

    2018-05-01

    The methods for increasing gas-turbine aircraft engines' (GTE) adaptive properties to interference based on empowerment of automatic control systems (ACS) are analyzed. The flow pulsation in suction and a discharge line of the compressor, which may cause the stall, are considered as the interference. The algorithmic solution to the problem of GTE pre-stall modes’ control adapted to stability boundary is proposed. The aim of the study is to develop the band-pass filtering algorithms to provide the detection functions of the compressor pre-stall modes for ACS GTE. The characteristic feature of pre-stall effect is the increase of pressure pulsation amplitude over the impeller at the multiples of the rotor’ frequencies. The used method is based on a band-pass filter combining low-pass and high-pass digital filters. The impulse response of the high-pass filter is determined through a known low-pass filter impulse response by spectral inversion. The resulting transfer function of the second order band-pass filter (BPF) corresponds to a stable system. The two circuit implementations of BPF are synthesized. Designed band-pass filtering algorithms were tested in MATLAB environment. Comparative analysis of amplitude-frequency response of proposed implementation allows choosing the BPF scheme providing the best quality of filtration. The BPF reaction to the periodic sinusoidal signal, simulating the experimentally obtained pressure pulsation function in the pre-stall mode, was considered. The results of model experiment demonstrated the effectiveness of applying band-pass filtering algorithms as part of ACS to identify the pre-stall mode of the compressor for detection of pressure fluctuations’ peaks, characterizing the compressor’s approach to the stability boundary.

  8. Outcomes, Approaches, and Challenges to Developing and Passing a Countywide Mandatory Vaccination Policy: St. Louis County's Experience with Hepatitis A Vaccine for Food Service Personnel.

    Science.gov (United States)

    Rebmann, Terri; Wilson, Kristin D; Loux, Travis; Iqbal, Ayesha Z; Peters, Eleanor B; Peavler, Olivia

    2016-01-01

    In the early 1990s, St. Louis County had multiple foodservice worker-related hepatitis A outbreaks uncontrolled by standard outbreak interventions. Restaurant interest groups and the general public applied political pressure to local public health officials for more stringent interventions, including a mandatory vaccination policy. Local health departments can enact mandatory vaccination policies, but this has rarely been done. The study objectives were to describe the approach used to pass a mandatory vaccination policy at the local jurisdiction level and illustrate the outcome from this ordinance 15 years later. A case study design was used. In-depth, semi-structured interviews using guided questions were conducted in spring, 2015, with six key informants who had direct knowledge of the mandatory vaccination policy process. Meeting minutes and/or reports were also analyzed. A Poisson distribution analysis was used to calculate the rate of outbreaks before and after mandatory vaccination policy implementation. The policy appears to have reduced the number of hepatitis A outbreaks, lowering the morbidity and economic burden in St. Louis County. The lessons learned by local public health officials in passing a mandatory hepatitis A vaccination policy are important and relevant in today's environment. The experience and lessons learned may assist other local health departments when faced with the potential need for mandatory policies for any vaccine preventable disease.

  9. In-situ characterization of symmetric dual-pass architecture of microfluidic co-laminar flow cells

    International Nuclear Information System (INIS)

    Ibrahim, Omar A.; Goulet, Marc-Antoni; Kjeang, Erik

    2016-01-01

    Highlights: • An analytical cell design is proposed for characterization of dual-pass flow cells • High power density up to 0.75 W cm −2 is demonstrated • The performance contributions of the inlet and outlet passes are of the same order • Downstream crossover is analyzed as a function of cell current and flow rate - Abstract: Microfluidic co-laminar flow cells with dual-pass architecture enable fuel recirculation and in-situ regeneration, and offer improvements in performance characteristics. In this work, a unique analytical cell design is proposed, with two split portions having flow-through porous electrodes. Each cell portion is first tested individually with vanadium redox species and the results are used to quantify the previously unknown crossover losses at the downstream portion of the cell, shown here to be a strong function of the flow rate. Moreover, the upstream cell portion demonstrates impressive room-temperature power density up to 0.75 W cm −2 at 1.0 A cm −2 , which is the highest performance reported to date for a microfluidic vanadium redox battery. Next, the two cell portions are connected in parallel to resemble a complete cell with dual-pass architecture, thereby enabling novel in-situ diagnostics of the inlet and outlet passes of the cell. For instance, the reactant utilization efficiency of the downstream cell portion is shown to be on the same order as that of the upstream portion at both low and high flow rates. Furthermore, in-situ regeneration is also demonstrated. Overall, the present results provide a deeper understanding of dual-pass reactant conversion and crossover which will be useful for future device optimization.

  10. A modeling of elementary passes taking into account the firing angle in abrasive water jet machining of titanium alloy

    Science.gov (United States)

    Bui, Van-Hung; Gilles, Patrick; Cohen, Guillaume; Rubio, Walter

    2018-05-01

    The use of titanium alloys in the aeronautical and high technology domains is widespread. The high strength and the low mass are two outstanding characteristics of titanium alloys which permit to produce parts for these domains. As other hard materials, it is challenging to generate 3D surfaces (e.g. pockets) when using conventional cutting methods. The development of Abrasive Water Jet Machining (AWJM) technology shows the capability to cut any kind of materials and it seems to be a good solution for such titanium materials with low specific force, low deformation of parts and low thermal shocks. Applying this technology for generating 3D surfaces requires to adopt a modelling approach. However, a general methodology results in complex models due to a lot of parameters of the machining process and based on numerous experiments. This study introduces an extended geometry model of an elementary pass when changing the firing angle during machining Ti-6AL-4V titanium alloy with a given machine configuration. Several experiments are conducted to observe the influence of major kinematic operating parameters, i.e. jet inclination angle (α) (perpendicular to the feed direction) and traverse speed (Vf). The material exposure time and the erosion capability of abrasives particles are affected directly by a variation of the traverse speed (Vf) and firing angle (α). These variations lead to different erosion rates along the kerf profile characterized by the depth and width of cut. A comparison demonstrated an efficiency of the proposed model for depth and width of elementary passes. Based on knowledge of the influence of both firing angle and traverse speed on the elementary pass shape, the proposed model allows to develop the simulation of AWJM process and paves a way for milling flat bottom pockets and 3D complex shapes.

  11. Detecting the severity of perinatal anxiety with the Perinatal Anxiety Screening Scale (PASS).

    Science.gov (United States)

    Somerville, Susanne; Byrne, Shannon L; Dedman, Kellie; Hagan, Rosemary; Coo, Soledad; Oxnam, Elizabeth; Doherty, Dorota; Cunningham, Nadia; Page, Andrew C

    2015-11-01

    The Perinatal Anxiety Screening Scale (PASS; Somerville et al., 2014) reliably identifies perinatal women at risk of problematic anxiety when a clinical cut-off score of 26 is used. This study aimed to identify a severity continuum of anxiety symptoms with the PASS to enhance screening, treatment and research for perinatal anxiety. Antenatal and postnatal women (n=410) recruited from the antenatal clinics and mental health services at an obstetric hospital completed the Edinburgh Postnatal Depression Scale (EPDS), the Depression, Anxiety and Stress Scale (DASS-21), the Spielberg State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory II (BDI), and the PASS. The women referred to mental health services were assessed to determine anxiety diagnoses via a diagnostic interview conducted by an experienced mental health professional from the Department of Psychological Medicine - King Edward Memorial Hospital. Three normative groups for the PASS, namely minimal anxiety, mild-moderate anxiety, and severe anxiety, were identified based on the severity of anxiety indicated on the standardised scales and anxiety diagnoses. Two cut-off points for the normative groups were calculated using the Jacobson-Truax method (Jacobson and Truax, 1991) resulting in three severity ranges: 'minimal anxiety'; 'mild-moderate anxiety'; and 'severe anxiety'. The most frequent diagnoses in the study sample were adjustment disorder, mixed anxiety and depression, generalised anxiety, and post-traumatic stress disorder. This may limit the generalisability of the severity range results to other anxiety diagnoses including obsessive compulsive disorder and specific phobia. Severity ranges for the PASS add value to having a clinically validated cut-off score in the detection and monitoring of problematic perinatal anxiety. The PASS can now be used to identify risk of an anxiety disorder and the severity ranges can indicate developing risk for early referrals for further assessments

  12. Pathogens in Sludge: A Case of Sufficient Challenge

    Energy Technology Data Exchange (ETDEWEB)

    Lesilind, R. Aarne

    2003-07-01

    There is increasing pressure in many countries to strengthen the regulations controlling the land disposal of wastewater sludges. In this paper I argue that although there is little doubt that sludges from wastewater treatment contain pathogenic organisms, not only are there no data to show that such disposal is a public health problem, but I want to suggest that small doses of pathogens in the environment provide a ''sufficient challenge'' that actually enhances public health. There therefore seems little reason, from a public health standpoint, to pass stricter sludge disposal regulations. (author)

  13. CO2 cost pass-through and windfall profits in the power sector

    International Nuclear Information System (INIS)

    Sijm, Jos; Neuhoff, Karsten; Yihsu Chen

    2006-01-01

    In order to cover their CO 2 emissions, power companies receive most of the required EU ETS allowances for free. In line with economic theory, these companies pass on the costs of these allowances in the price of electricity. This article analyses the implications of the EU ETS for the power sector, notably the impact of free allocation of CO 2 emission allowances on the price of electricity and the profitability of power generation. As well as some theoretical reflections, the article presents empirical and model estimates of CO 2 cost pass-through for Germany and The Netherlands, indicating that pass-through rates vary between 60 and 100% of CO 2 costs, depending on the carbon intensity of the marginal production unit and various other market- or technology-specific factors. As a result, power companies realize substantial windfall profits, as indicated by the empirical and model estimates presented in the article. (Author)

  14. Per-beam, planar IMRT QA passing rates do not predict clinically relevant patient dose errors

    Energy Technology Data Exchange (ETDEWEB)

    Nelms, Benjamin E.; Zhen Heming; Tome, Wolfgang A. [Canis Lupus LLC and Department of Human Oncology, University of Wisconsin, Merrimac, Wisconsin 53561 (United States); Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53705 (United States); Departments of Human Oncology, Medical Physics, and Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53792 (United States)

    2011-02-15

    Purpose: The purpose of this work is to determine the statistical correlation between per-beam, planar IMRT QA passing rates and several clinically relevant, anatomy-based dose errors for per-patient IMRT QA. The intent is to assess the predictive power of a common conventional IMRT QA performance metric, the Gamma passing rate per beam. Methods: Ninety-six unique data sets were created by inducing four types of dose errors in 24 clinical head and neck IMRT plans, each planned with 6 MV Varian 120-leaf MLC linear accelerators using a commercial treatment planning system and step-and-shoot delivery. The error-free beams/plans were used as ''simulated measurements'' (for generating the IMRT QA dose planes and the anatomy dose metrics) to compare to the corresponding data calculated by the error-induced plans. The degree of the induced errors was tuned to mimic IMRT QA passing rates that are commonly achieved using conventional methods. Results: Analysis of clinical metrics (parotid mean doses, spinal cord max and D1cc, CTV D95, and larynx mean) vs IMRT QA Gamma analysis (3%/3 mm, 2/2, 1/1) showed that in all cases, there were only weak to moderate correlations (range of Pearson's r-values: -0.295 to 0.653). Moreover, the moderate correlations actually had positive Pearson's r-values (i.e., clinically relevant metric differences increased with increasing IMRT QA passing rate), indicating that some of the largest anatomy-based dose differences occurred in the cases of high IMRT QA passing rates, which may be called ''false negatives.'' The results also show numerous instances of false positives or cases where low IMRT QA passing rates do not imply large errors in anatomy dose metrics. In none of the cases was there correlation consistent with high predictive power of planar IMRT passing rates, i.e., in none of the cases did high IMRT QA Gamma passing rates predict low errors in anatomy dose metrics or vice versa

  15. McMPI – a managed-code message passing interface library for high performance communication in C#

    OpenAIRE

    Holmes, Daniel John

    2012-01-01

    This work endeavours to achieve technology transfer between established best-practice in academic high-performance computing and current techniques in commercial high-productivity computing. It shows that a credible high-performance message-passing communication library, with semantics and syntax following the Message-Passing Interface (MPI) Standard, can be built in pure C# (one of the .Net suite of computer languages). Message-passing has been the dominant paradigm in high-pe...

  16. A study of estimating cutting depth for multi-pass nanoscale cutting by using atomic force microscopy

    International Nuclear Information System (INIS)

    Lin, Zone-Ching; Hsu, Ying-Chih

    2012-01-01

    This paper studies two models for estimating cutting depth of multi-pass nanoscale cutting by using an atomic force microscopy (AFM) probe. One estimates cutting depth for multi-pass nanoscale cutting by using regression equations of nanoscale contact pressure factor (NCP factor) while the other uses equation of specific down force energy (SDFE). This paper proposes taking a diamond-coated probe of AFM as the cutting tool to carry out multi-pass nanoscale cutting experiments on the surface of sapphire substrate. In the process of experimentation, different down forces are set, and the probe shape of AFM is known, then using each down force to multi-pass cutting the sapphire substrate. From the measured experimental data of a central cutting depth of the machining groove by AFM, this paper calculates the specific down force energy of each down force. The experiment results reveal that the specific down force energy of each case of multi-pass nanoscale cutting for different down forces under a probe of AFM is close to a constant value. This paper also compares the nanoscale cutting results from estimating cutting depths for each pass of multi-pass among the experimental results and the calculating results obtained by the two theories models. It is found that the model of specific down force energy can calculate cutting depths for each nanoscale cutting pass by one equation. It is easier to use than the multi-regression equations of the nanoscale contact pressure factor. Besides, the estimations of cutting depth results obtained by the model of specific down force energy are closer to that of the experiment results. It shows that the proposed specific down force energy model in this paper is an acceptable model.

  17. Feasibility study of multi-pass respiratory-gated helical tomotherapy of a moving target via binary MLC closure

    Science.gov (United States)

    Kim, Bryan; Chen, Jeff; Kron, Tomas; Battista, Jerry

    2010-11-01

    Gated radiotherapy of lung lesions is particularly complex for helical tomotherapy, due to the simultaneous motions of its three subsystems (gantry, couch and collimator). We propose a new way to implement gating for helical tomotherapy, namely multi-pass respiratory gating. In this method, gating is achieved by delivering only the beam projections that occur within a respiratory gating window, while blocking the rest of the beam projections by fully closing all collimator leaves. Due to the continuous couch motion, the planned beam projections must be delivered over multiple passes of radiation deliveries. After each pass, the patient couch is reset to its starting position, and the treatment recommences at a different phase of tumour motion to 'fill in' the previously blocked beam projections. The gating process may be repeated until the plan dose is delivered (full gating), or halted after a certain number of passes, with the entire remaining dose delivered in a final pass without gating (partial gating). The feasibility of the full gating approach was first tested for sinusoidal target motion, through experimental measurements with film and computer simulation. The optimal gating parameters for full and partial gating methods were then determined for various fractionation schemes through computer simulation, using a patient respiratory waveform. For sinusoidal motion, the PTV dose deviations of -29 to 5% observed without gating were reduced to range from -1 to 3% for a single fraction, with a 4 pass full gating. For a patient waveform, partial gating required fewer passes than full gating for all fractionation schemes. For a single fraction, the maximum allowed residual motion was only 4 mm, requiring large numbers of passes for both full (12) and partial (7 + 1) gating methods. The number of required passes decreased significantly for 3 and 30 fractions, allowing residual motion up to 7 mm. Overall, the multi-pass gating technique was shown to be a promising

  18. Feasibility study of multi-pass respiratory-gated helical tomotherapy of a moving target via binary MLC closure

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bryan; Chen, Jeff; Battista, Jerry [London Regional Cancer Program, London Health Sciences Centre, London, ON (Canada); Kron, Tomas, E-mail: bryan.kim@lhsc.on.c [Peter MacCallum Cancer Center, Melbourne (Australia)

    2010-11-21

    Gated radiotherapy of lung lesions is particularly complex for helical tomotherapy, due to the simultaneous motions of its three subsystems (gantry, couch and collimator). We propose a new way to implement gating for helical tomotherapy, namely multi-pass respiratory gating. In this method, gating is achieved by delivering only the beam projections that occur within a respiratory gating window, while blocking the rest of the beam projections by fully closing all collimator leaves. Due to the continuous couch motion, the planned beam projections must be delivered over multiple passes of radiation deliveries. After each pass, the patient couch is reset to its starting position, and the treatment recommences at a different phase of tumour motion to 'fill in' the previously blocked beam projections. The gating process may be repeated until the plan dose is delivered (full gating), or halted after a certain number of passes, with the entire remaining dose delivered in a final pass without gating (partial gating). The feasibility of the full gating approach was first tested for sinusoidal target motion, through experimental measurements with film and computer simulation. The optimal gating parameters for full and partial gating methods were then determined for various fractionation schemes through computer simulation, using a patient respiratory waveform. For sinusoidal motion, the PTV dose deviations of -29 to 5% observed without gating were reduced to range from -1 to 3% for a single fraction, with a 4 pass full gating. For a patient waveform, partial gating required fewer passes than full gating for all fractionation schemes. For a single fraction, the maximum allowed residual motion was only 4 mm, requiring large numbers of passes for both full (12) and partial (7 + 1) gating methods. The number of required passes decreased significantly for 3 and 30 fractions, allowing residual motion up to 7 mm. Overall, the multi-pass gating technique was shown to be a

  19. ABO blood type correlates with survival on prostate cancer vaccine therapy.

    Science.gov (United States)

    Muthana, Saddam M; Gulley, James L; Hodge, James W; Schlom, Jeffrey; Gildersleeve, Jeffrey C

    2015-10-13

    Immunotherapies for cancer are transforming patient care, but clinical responses vary considerably from patient to patient. Simple, inexpensive strategies to target treatment to likely responders could substantially improve efficacy while simultaneously reducing health care costs, but identification of reliable biomarkers has proven challenging. Previously, we found that pre-treatment serum IgM to blood group A (BG-A) correlated with survival for patients treated with PROSTVAC-VF, a therapeutic cancer vaccine in phase III clinical trials for the treatment of prostate cancer. These results suggested that ABO blood type might influence efficacy. Unfortunately, blood types were not available in the clinical records for all but 8 patients and insufficient amounts of sera were left for standard blood typing methods. To test the hypothesis, therefore, we developed a new glycan microarray-based method for determining ABO blood type. The method requires only 4 μL of serum, provides 97% accuracy, and allows simultaneous profiling of many other serum anti-glycan antibodies. After validation with 220 healthy subjects of known blood type, the method was then applied to 74 PROSTVAC-VF patients and 37 control patients from a phase II trial. In this retrospective study, we found that type B and O PROSTVAC-VF patients demonstrated markedly improved clinical outcomes relative to A and AB patients, including longer median survival, longer median survival relative to Halabi predicted survival, and improved overall survival via Kaplan-Meier survival analysis (p = 0.006). Consequently, blood type may provide an inexpensive screen to pre-select patients likely to benefit from PROSTVAC-VF therapy.

  20. Three dimensional multi-pass repair weld simulations

    International Nuclear Information System (INIS)

    Elcoate, C.D.; Dennis, R.J.; Bouchard, P.J.; Smith, M.C.

    2005-01-01

    Full 3-dimensional (3-D) simulation of multi-pass weld repairs is now feasible and practical given the development of improved analysis tools and significantly greater computer power. This paper presents residual stress results from 3-D finite element (FE) analyses simulating a long (arc length of 62 deg. ) and a short (arc length of 20 deg. ) repair to a girth weld in a 19.6 mm thick, 432 mm outer diameter cylindrical test component. Sensitivity studies are used to illustrate the importance of weld bead inter-pass temperature assumptions and to show where model symmetry can be used to reduce the analysis size. The predicted residual stress results are compared with measured axial, hoop and radial through-wall profiles in the heat affected zone of the test component repairs. A good overall agreement is achieved between neutron diffraction and deep hole drilling measurements and the prediction at the mid-length position of the short repair. These results demonstrate that a coarse 3-D FE model, using a 'block-dumped' weld bead deposition approach (rather than progressively depositing weld metal), can accurately capture the important components of a short repair weld residual stress field. However, comparisons of measured with predicted residual stress at mid-length and stop-end positions in the long repair are less satisfactory implying some shortcomings in the FE modelling approach that warrant further investigation

  1. The 150 Credit-Hour Requirement and CPA Examination Pass Rates--A Four Year Study

    Science.gov (United States)

    Briggs, Gary P.; He, Lerong

    2012-01-01

    Debate concerning the minimum educational requirements of certified public accountant (CPA) candidates in the USA has been taking place for decades. This paper compares the sectional pass rates of CPA candidates from jurisdictions requiring 150 credit hours of college study with the pass rates of candidates from jurisdictions not requiring 150…

  2. 78 FR 18479 - Drawbridge Operation Regulations; Pass Manchac, LA

    Science.gov (United States)

    2013-03-27

    ... governing the operation of the Canadian National (CN) Railroad automated bascule span drawbridge across Pass....gov . Type the docket number in the ``SEARCH'' box and click ``SEARCH.'' Click on Open Docket Folder... Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The CN Railroad has requested a temporary...

  3. exchange rate pass-through to import and consumer prices

    African Journals Online (AJOL)

    Eyerusalem

    degree of pass-through is estimated by the means of impulse response functions. ..... through from exchange rate fluctuations to each stage of the distribution chain ..... exclusion test (which is asymptotically chi-square distributed) and the results ...... Endogenous variables: DLWCPI YGap DLNEER DLMPI DLCPI DLM2. Root.

  4. Highly efficient single-pass sum frequency generation by cascaded nonlinear crystals

    DEFF Research Database (Denmark)

    Hansen, Anders Kragh; Andersen, Peter E.; Jensen, Ole Bjarlin

    2015-01-01

    , despite differences in the phase relations of the involved fields. An unprecedented 5.5 W of continuous-wave diffraction-limited green light is generated from the single-pass sum frequency mixing of two diode lasers in two periodically poled nonlinear crystals (conversion efficiency 50%). The technique......The cascading of nonlinear crystals has been established as a simple method to greatly increase the conversion efficiency of single-pass second-harmonic generation compared to a single-crystal scheme. Here, we show for the first time that the technique can be extended to sum frequency generation...... is generally applicable and can be applied to any combination of fundamental wavelengths and nonlinear crystals....

  5. Uji Empiris Mekanisme Transmisi Kebijakan Moneter: Interest Rate Pass-through Sektor Perbankan Indonesia

    OpenAIRE

    Wibowo, Buddi; Lazuardi, Eduardo

    2016-01-01

    Empirical Evidence of Monetary Policy Transmission Mechanism: Indonesia Banking Sector Interest Rate Pass-throughRobust measurement of interest rates speed of adjustment to monetary policy changes is very important to obtain acomprehensive understanding on the monetary transmission process and the eectiveness of monetary policy. The speed of adjustment are determined by number of frictions that interfere with the transmission of monetary policy.We measure Indonesia interest rate pass-through ...

  6. Prognostic factors and survival in primary malignant astrocytomas of the spinal cord: a population-based analysis from 1973 to 2007.

    Science.gov (United States)

    Adams, Hadie; Avendaño, Javier; Raza, Shaan M; Gokaslan, Ziya L; Jallo, George I; Quiñones-Hinojosa, Alfredo

    2012-05-20

    Observational cross-sectional study. Using data from the population-based cancer registries of the Surveillance, Epidemiology and End Results (SEER) program, we analyzed demographic features, tumor and treatment characteristics, as well as survival rates in patients with primary malignant astrocytomas of the spinal cord (PMASC). PMASC is a rare neoplasm and is considered to carry the same dismal outcome as their cerebral counterparts. Our current knowledge is incomplete, and understanding the epidemiology, diagnosis, and optimal treatment still poses challenges. The SEER data from 1973 to 2007 were reviewed for pathologically confirmed primary anaplastic astrocytomas (AA) and glioblastomas of the spinal cord (C72.0). We compared the clinical features and outcomes of the cohort in uni- and multivariate fashion. Survival was calculated and compared using Kaplan-Meier curves and log-rank analysis. Our search criteria retrieved 135 patients diagnosed with PMASC. The median survival for PMASC was 13 months with 1-, 2-, and 5-year survival rates of 51.8%, 32.2%, and 18.7%. Patient diagnosed with AA had a median survival time of 17 months versus 10 months in patients diagnosed with glioblastomas. Adult patients observed markedly prolonged survival compared with the pediatric group, with a 16-month versus 9-month median survival, respectively. Multivariate analysis revealed age at diagnosis, pediatric and adult age groups, sex, tumor histology, and extent of resection as significant predictors of survival. Interestingly, outcomes did not significantly change throughout the last decades or by receiving radiotherapy. Outcome for patients diagnosed with PMASC remains poor and presents an ongoing challenge for professionals in the field of neurospinal medicine and surgery. In our analyses of AA, adult patients, males, and patients undergoing radical resections were associated with increased survival. However, incidence of these lesions is low; hence, building strong

  7. Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Devine, Matthew S; Ballard, Emma; O'Rourke, Peter; Kiernan, Matthew C; Mccombe, Pamela A; Henderson, Robert D

    2016-01-01

    Estimating survival in amyotrophic lateral sclerosis (ALS) is challenging due to heterogeneity in clinical features of disease and a lack of suitable markers that predict survival. Our aim was to determine whether scoring of upper or lower motor neuron weakness is associated with survival. With this objective, 161 ALS subjects were recruited from two tertiary referral centres. Scoring of upper (UMN) and lower motor neuron (LMN) signs was performed, in addition to a brief questionnaire. Subjects were then followed until the censorship date. Univariate analysis was performed to identify variables associated with survival to either non-invasive ventilation (NIV) or death, which were then further characterized using Cox regression. Results showed that factors associated with reduced survival included older age, bulbar and respiratory involvement and shorter diagnostic delay (all p NIV or death (p ≤0.001) whereas UMN scores were poorly associated with survival. In conclusion, our results suggest that, early in disease assessment and in the context of other factors (age, bulbar, respiratory status), the burden of LMN weakness provides an accurate estimate of outcome. Such a scoring system could predict prognosis, and thereby aid in selection of patients for clinical trials.

  8. Interest Rate Pass-through in Sri Lanka

    OpenAIRE

    Amarasekara, Chandranath

    2005-01-01

    The Central Bank of Sri Lanka has increasingly been relying on interest rates as the instrument for conducting monetary policy. Changes to the key monetary policy variables, the Repo and the Reverse Repo rates, are initially expected to be reflected in the OMO rates and the call money market rates, before being passedthrough to commercial bank retail interest rates. It is important to obtain a good understanding of the speed and magnitude of the interest rate pass-through to make timely monet...

  9. EFICYENCY OF THE BALL PASSES IN THE FINALE SOCCER MATCH IN THE EUROPENA CHAMPIONSHIP ,,EURO 2008”

    Directory of Open Access Journals (Sweden)

    Bylbyl Sokoli

    2011-03-01

    Full Text Available The modern soccer has a wide variability and complexity of the technical-tactical and motoric elements during the game, which are oriented in increasing the tempo, efficiency, dynamics, attractiveness and success in competition. In this work was analyzed the sample of 27 soccer players from two national teams: the national team of Spain and the national team of Germany, the first and second ranged team in the European championship ,,EURO 2008 “ With the information gathered with the ,,Castrol Performance Index“ ,it was possible to express a different situational parameters in all stages of game . There were drown out the information’s about the kinds and number of passes of the team and the players, the percentage of the efficiency of the team, and for each player of each team .The main issue of the work was to investigate and to describe competitive efficiency of the players and teams, respectively, competitive efficiency of the players, and the finalist teams in the last European championship, with the special focus to passes. According to the results the team of Spain in final match has as paid attention to the all kinds of ball passes. According to the form of the ball pass the team of Germany has dominated in the middle passes, train to engage the offense players with those passes .According the accuracy of pass execution, the team of Spain had the higher accuracy in short passes, which is reasonable after the goal achievement, where as prime aim was to keep the advantage in result

  10. Modelling survival

    DEFF Research Database (Denmark)

    Ashauer, Roman; Albert, Carlo; Augustine, Starrlight

    2016-01-01

    The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts for time-variable exposure to the stressor. We performed three studies to test...

  11. Struggling to survive: early life challenges in relation to the backtest in pigs

    NARCIS (Netherlands)

    Camerlink, I.; Ursinus, W.W.; Bolhuis, J.E.

    2014-01-01

    Intensively reared piglets may face many early life challenges and these may affect behavior. The objective of this study was to examine the relationship between piglets’ early life circumstances and their behavioral response in a backtest. Hereto, 992 piglets of 14 d of age were subjected to a

  12. Academic performance and pass rates: Comparison of three first ...

    African Journals Online (AJOL)

    First year students' academic performance in three Life Science courses (Botany, Zoology and Bioscience) was compared. Pass rates, as well as the means and distributions of final marks were analysed. Of the three components (coursework, practical and theory examinations) contributing to the final mark of each course, ...

  13. STRUCTURE OF ECAP ALUMINIUM AFTER DIFFERENT NUMBER OF PASSES

    Directory of Open Access Journals (Sweden)

    Lucia Ilucová

    2011-05-01

    Full Text Available The structure of high purity (99.99% aluminium processed by equal channel angular pressing in the as pressed state after different number of passes was examined using various stereological methods. An extreme inhomogeneity and complicated anisotropy was observed along the body of rod-like specimens.

  14. Positron emission tomography of hepatic first-pass metabolism of ammonia in pig

    DEFF Research Database (Denmark)

    Keiding, S; Munk, O L; Roelsgaard, K

    2001-01-01

    Hepatic first-pass metabolism plays a key role in metabolic regulation and drug metabolism. Metabolic processes can be quantified in vivo by positron emission tomography scanning (PET). We wished to develop a PET technique to measure hepatic first-pass metabolism of ammonia. Seven anaesthetised...... pigs were given positron-labelled ammonia, (13)NH(3), into the portal vein and into the vena cava as successive 2-min infusions followed by 22-min dynamic liver scanning. Vena cava infusion data were used to account for recirculation of tracer and metabolites following the portal vein infusion...

  15. Stagnant loop syndrome resulting from small-bowel irradiation injury and intestinal by-pass

    International Nuclear Information System (INIS)

    Swan, R.W.

    1974-01-01

    Stagnant or blind-loop syndrome includes vitamin B12 malabsorption, steatorrhea, and bacterial overgrowth of the small intestine. A case is presented to demonstrate this syndrome occurring after small-bowel irradiation injury with exaggeration postenterocolic by-pass. Alteration of normal small-bowel flora is basic to development of the stagnant-loop syndrome. Certain strains of bacteria as Bacteriodes and E. coli are capable of producing a malabsorption state. Definitive therapy for this syndrome developing after severe irradiation injury and intestinal by-pass includes antibiotics. Rapid symptomatic relief from diarrhea and improved malabsorption studies usually follow appropriate antibiotic therapy. Recolonization of the loop(s) with the offending bacterial species may produce exacerbation of symptoms. Since antibiotics are effective, recognition of this syndrome is important. Foul diarrheal stools should not be considered a necessary consequence of irradiation injury and intestinal by-pass

  16. Cooperative breeding shapes post-fledging survival in an Afrotropical forest bird.

    Science.gov (United States)

    Van de Loock, Dries; Strubbe, Diederik; De Neve, Liesbeth; Githiru, Mwangi; Matthysen, Erik; Lens, Luc

    2017-05-01

    For avian group living to be evolutionary stable, multiple fitness benefits are expected. Yet, the difficulty of tracking fledglings, and thus estimating their survival rates, limits our knowledge on how such benefits may manifest postfledging. We radio-tagged breeding females of the Afrotropical cooperatively breeding Placid greenbul ( Phyllastrephus placidus) during nesting. Tracking these females after fledging permitted us to locate juvenile birds, their parents, and any helpers present and to build individual fledgling resighting datasets without incurring mortality costs or causing premature fledging due to handling or transmitter effects. A Bayesian framework was used to infer age-specific mortality rates in relation to group size, fledging date, maternal condition, and nestling condition. Postfledging survival was positively related to group size, with fledglings raised in groups with four helpers showing nearly 30% higher survival until independence compared with pair-only offspring, independent of fledging date, maternal condition or nestling condition. Our results demonstrate the importance of studying the early dependency period just after fledging when assessing presumed benefits of cooperative breeding. While studying small, mobile organisms after they leave the nest remains highly challenging, we argue that the telemetric approach proposed here may be a broadly applicable method to obtain unbiased estimates of postfledging survival.

  17. Forest Analysis by Single-Pass Millimeterwave SAR Tomography

    OpenAIRE

    Schmitt, Michael; Zhu, Xiao Xiang

    2016-01-01

    Recent investigations show that millimeterwave SAR tomography provides an interesting means for the analysis of forested areas, especially if single-pass systems are employed. Providing very high resolutions in the decimeter domain and highly coherent data also for slightly windy conditions, even individual trees can be considered. Besides, it has been shown that a certain amount of canopy penetration is possible in spite of the short wavelength.

  18. A New One-Pass Transformation into Monadic Normal Form

    DEFF Research Database (Denmark)

    Danvy, Olivier

    2003-01-01

    We present a translation from the call-by-value λ-calculus to monadic normal forms that includes short-cut boolean evaluation. The translation is higher-order, operates in one pass, duplicates no code, generates no chains of thunks, and is properly tail recursive. It makes a crucial use of symbolic...

  19. Evaluation of allograft perfusion by radionuclide first-pass study in renal failure following renal transplantation

    International Nuclear Information System (INIS)

    Baillet, G.; Ballarin, J.; Urdaneta, N.; Campos, H.; Vernejoul, P. de; Fermanian, J.; Kellershohn, C.; Kreis, H.

    1986-01-01

    To assess the diagnostic value of indices measured on a first-pass curve, we performed 72 radionuclide renal first-pass studies (RFP) in 21 patients during the early weeks following renal allograft transplantation. The diagnosis was based on standard clinical and biochemical data and on fine needle aspiration biopsy (FNAB) of the transplant. Aortic and renal first-pass curves were filtered using a true low-pass filter and five different indices of renal perfusion were computed, using formulae from the literature. Statistical analysis performed on the aortic and renal indices indicated excellent reproducibility of the isotopic study. Although renal indices presented a rather large scatter, they all discriminated well between normal and rejection. Three indices have a particularly good diagnostic value. In the discrimination between rejection and Acute Tubular Necrosis (ATN), only one index gave satisfying results. The indices, however, indicate that there are probably ATN with an alternation of renal perfusion and rejection episodes where perfusion is almost intact. We conclude that radionuclide first-pass study allows accurate and reproducible quantitation of renal allograft perfusion. The measured parameters are helpful to follow up the course of a post-transplantation renal failure episode and to gain more insight into renal ischemia following transplantation. (orig.)

  20. Plea to lower English test pass marks for EEA nurses.

    Science.gov (United States)

    Longhurst, Chris

    2017-08-09

    Nurses from a group campaigning for the rights of EU citizens in the UK after Brexit are meeting the Nursing and Midwifery Council (NMC) to press for the pass mark for English language tests to be lowered.

  1. Energy and exergy analysis in double-pass solar air heater

    Indian Academy of Sciences (India)

    P VELMURUGAN

    mesh) in the second pass, and also by mounting longitudinal fins in the back side of the absorber plate ( ... energy sources. ... indoor solar simulator test facility photographically shown ..... El-khawajah et al [19] who employed multiple parallel.

  2. Recovery of endo-CFU-S in radio-adaptive survival response in mice

    International Nuclear Information System (INIS)

    Yonezawa, Morio; Horie, Kiyohito; Kubo, Kihei

    2003-01-01

    A priming irradiation with 0.45 Gy of X-rays, given 2 weeks prior to the challenging exposures, induces radio-resistance (decrease in bone marrow death rate after mid-lethal irradiations) in mice of C57BL/6 mice. This acquired radio-resistance appeared on day 9 and continued till day 17 after the priming irradiation, with a maximal on days 12-14 and diminished on day 21. The priming irradiation, given 14 days prior to the challenging exposure, increased endogenous spleen colonies on days 12-13 after exposure to 5.0 Gy. Effect of interval time between the priming and the challenging irradiations on the increase in endogenous spleen colonies was also examined. Significant increase of the colonies by the priming irradiation was observed when the interval time was 12-17 and 21 days. The results correspond to the increase of the survival rates on days 12-17 after the challenging irradiations. (author)

  3. Id1 expression promotes peripheral CD4{sup +} T cell proliferation and survival upon TCR activation without co-stimulation

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Chen; Jin, Rong [Department of Immunology, Peking University Health Science Center, Beijing (China); Wang, Hong-Cheng [Oklahoma Medical Research Foundation, Oklahoma City, OK (United States); Tang, Hui; Liu, Yuan-Feng; Qian, Xiao-Ping; Sun, Xiu-Yuan; Ge, Qing [Department of Immunology, Peking University Health Science Center, Beijing (China); Sun, Xiao-Hong, E-mail: sunx@omrf.org [Oklahoma Medical Research Foundation, Oklahoma City, OK (United States); Zhang, Yu, E-mail: zhangyu007@bjmu.edu.cn [Department of Immunology, Peking University Health Science Center, Beijing (China)

    2013-06-21

    Highlights: •Id1 expression enables naïve T cell proliferation without anti-CD28 co-stimulation. •Id1 expression facilitates T cells survival when stimulated with anti-CD3. •Elevation of IL-2 production by Id1 contributes increased proliferation and survival. •Id1 potentiates NF-κB activation by anti-CD3 stimulation. -- Abstract: Although the role of E proteins in the thymocyte development is well documented, much less is known about their function in peripheral T cells. Here we demonstrated that CD4 promoter-driven transgenic expression of Id1, a naturally occurring dominant-negative inhibitor of E proteins, can substitute for the co-stimulatory signal delivered by CD28 to facilitate the proliferation and survival of naïve CD4{sup +} cells upon anti-CD3 stimulation. We next discovered that IL-2 production and NF-κB activity after anti-CD3 stimulation were significantly elevated in Id1-expressing cells, which may be, at least in part, responsible for the augmentation of their proliferation and survival. Taken together, results from this study suggest an important role of E and Id proteins in peripheral T cell activation. The ability of Id proteins to by-pass co-stimulatory signals to enable T cell activation has significant implications in regulating T cell immunity.

  4. [Impact of passing items above the ceiling on the assessment results of Peabody developmental motor scales].

    Science.gov (United States)

    Zhao, Gai; Bian, Yang; Li, Ming

    2013-12-18

    To analyze the impact of passing items above the roof level in the gross motor subtest of Peabody development motor scales (PDMS-2) on its assessment results. In the subtests of PDMS-2, 124 children from 1.2 to 71 months were administered. Except for the original scoring method, a new scoring method which includes passing items above the ceiling were developed. The standard scores and quotients of the two scoring methods were compared using the independent-samples t test. Only one child could pass the items above the ceiling in the stationary subtest, 19 children in the locomotion subtest, and 17 children in the visual-motor integration subtest. When the scores of these passing items were included in the raw scores, the total raw scores got the added points of 1-12, the standard scores added 0-1 points and the motor quotients added 0-3 points. The diagnostic classification was changed only in two children. There was no significant difference between those two methods about motor quotients or standard scores in the specific subtest (P>0.05). The passing items above a ceiling of PDMS-2 isn't a rare situation. It usually takes place in the locomotion subtest and visual-motor integration subtest. Including these passing items into the scoring system will not make significant difference in the standard scores of the subtests or the developmental motor quotients (DMQ), which supports the original setting of a ceiling established by upassing 3 items in a row. However, putting the passing items above the ceiling into the raw score will improve tracking of children's developmental trajectory and intervention effects.

  5. Evaluation of Two Passes Cold Pilgering Property for PLUS7TM Guide Thimble and Instrumentation Tubing

    Energy Technology Data Exchange (ETDEWEB)

    Park, Min Young; Park, Ki Bum; Kim, In Kyu; Lee, Young Hee; Kahng, Jong Yeol [KEPCO Nuclear Fuel Co., Daejeon (Korea, Republic of)

    2015-05-15

    The thermo-mechanical property of zirconium alloy tube is well known to be influenced by pilgering pass schedule and its tooling; thus the control of its microstructure and mechanical property in the final tube production stage for nuclear fuel applications is a major concern of tube manufacture. To fabricate final tube, the 3 passes pilgering is applied in general by using TREX(Tube Reduced EXtrusion), 63.5mm outer diameter(OD), in KEPCO NF and most of Zr tube manufacturing companies. They are also taking big efforts to reduce pilgering step for the sake of increasing the efficiency of production in the forming stage of tube. The objective of this study is to develop two passes of pilgering schedule from the conventional three passes of pilgering schedule for manufacturing the Guide Thimble and Instrumentation tube conforming to specification, which are newly developing component for the advanced nuclear fuel assembly in KEPCO NF. CSR, hydride orientation, and structural integrity are well conformed to the desired targets so it is expected that both die and mandrel were newly designed for the PLUS7TM guide thimble and instrumentation tube with higher Q factor for two passes of pilgering at 50LC and 25LC pilger machine, instead of three passes of pilgering, are able to be applicable to this design of fuel component. If developed two passes pilgering is applied to current manufacturing process, it would improve not only productivity but also yield rate by reducing 3 steps(pilgering, heat-treatment, pickiling and cleaning) of manufacturing process. But additional tests(including in-pile test) should be performed in order to evaluate integrity in reactor.

  6. Using Partial Reconfiguration and Message Passing to Enable FPGA-Based Generic Computing Platforms

    Directory of Open Access Journals (Sweden)

    Manuel Saldaña

    2012-01-01

    Full Text Available Partial reconfiguration (PR is an FPGA feature that allows the modification of certain parts of an FPGA while the rest of the system continues to operate without disruption. This distinctive characteristic of FPGAs has many potential benefits but also challenges. The lack of good CAD tools and the deep hardware knowledge requirement result in a hard-to-use feature. In this paper, the new partition-based Xilinx PR flow is used to incorporate PR within our MPI-based message-passing framework to allow hardware designers to create template bitstreams, which are predesigned, prerouted, generic bitstreams that can be reused for multiple applications. As an example of the generality of this approach, four different applications that use the same template bitstream are run consecutively, with a PR operation performed at the beginning of each application to instantiate the desired application engine. We demonstrate a simplified, reusable, high-level, and portable PR interface for X86-FPGA hybrid machines. PR issues such as local resets of reconfigurable modules and context saving and restoring are addressed in this paper followed by some examples and preliminary PR overhead measurements.

  7. PENGARUH LATIHAN POWER OTOT LENGAN TERHADAP KEMAMPUAN CHEST PASS BOLA BASKET SMP TRI BHAKTI PEKANBARU

    Directory of Open Access Journals (Sweden)

    M. Fransazeli Makorohim

    2016-02-01

    Full Text Available This study aims to find out about how much influence of muscle power training arm of the ability of basketball Chest passjunior high school students’ extracurricular son of tri bhakti pekanbaru. This study is an experiment that uses the Chest pass test before and after exercise. The study was conducted of Tri Bhakti Pekanbaru. The research data gathered through the data Pree and post test and treated with t-test technique. The analysis shows encountered in the study between Pree test and post test students’ ability to Chest pass significance level. Based on these data it is clear that the alternative hypothesis is accepted that are significant influence of muscle power training arm of the ability of basketball Chest pass junior high school students’ extracurricular Tri Bhakti Pekanbaru. Thus the results of research done to say that exercise variation influence of muscle power training arm of the ability of basketball Chest pass junior high school students’ extracurricular of Tri Bhakti Pekanbaru.

  8. Beam dynamics simulation of a double pass proton linear accelerator

    Directory of Open Access Journals (Sweden)

    Kilean Hwang

    2017-04-01

    Full Text Available A recirculating superconducting linear accelerator with the advantage of both straight and circular accelerator has been demonstrated with relativistic electron beams. The acceleration concept of a recirculating proton beam was recently proposed [J. Qiang, Nucl. Instrum. Methods Phys. Res., Sect. A 795, 77 (2015NIMAER0168-900210.1016/j.nima.2015.05.056] and is currently under study. In order to further support the concept, the beam dynamics study on a recirculating proton linear accelerator has to be carried out. In this paper, we study the feasibility of a two-pass recirculating proton linear accelerator through the direct numerical beam dynamics design optimization and the start-to-end simulation. This study shows that the two-pass simultaneous focusing without particle losses is attainable including fully 3D space-charge effects through the entire accelerator system.

  9. SU-F-T-301: Planar Dose Pass Rate Inflation Due to the MapCHECK Measurement Uncertainty Function

    International Nuclear Information System (INIS)

    Bailey, D; Spaans, J; Kumaraswamy, L; Podgorsak, M

    2016-01-01

    Purpose: To quantify the effect of the Measurement Uncertainty function on planar dosimetry pass rates, as analyzed with Sun Nuclear Corporation analytic software (“MapCHECK” or “SNC Patient”). This optional function is toggled on by default upon software installation, and automatically increases the user-defined dose percent difference (%Diff) tolerance for each planar dose comparison. Methods: Dose planes from 109 IMRT fields and 40 VMAT arcs were measured with the MapCHECK 2 diode array, and compared to calculated planes from a commercial treatment planning system. Pass rates were calculated within the SNC analytic software using varying calculation parameters, including Measurement Uncertainty on and off. By varying the %Diff criterion for each dose comparison performed with Measurement Uncertainty turned off, an effective %Diff criterion was defined for each field/arc corresponding to the pass rate achieved with MapCHECK Uncertainty turned on. Results: For 3%/3mm analysis, the Measurement Uncertainty function increases the user-defined %Diff by 0.8–1.1% average, depending on plan type and calculation technique, for an average pass rate increase of 1.0–3.5% (maximum +8.7%). For 2%, 2 mm analysis, the Measurement Uncertainty function increases the user-defined %Diff by 0.7–1.2% average, for an average pass rate increase of 3.5–8.1% (maximum +14.2%). The largest increases in pass rate are generally seen with poorly-matched planar dose comparisons; the MapCHECK Uncertainty effect is markedly smaller as pass rates approach 100%. Conclusion: The Measurement Uncertainty function may substantially inflate planar dose comparison pass rates for typical IMRT and VMAT planes. The types of uncertainties incorporated into the function (and their associated quantitative estimates) as described in the software user’s manual may not accurately estimate realistic measurement uncertainty for the user’s measurement conditions. Pass rates listed in published

  10. SU-F-T-301: Planar Dose Pass Rate Inflation Due to the MapCHECK Measurement Uncertainty Function

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, D [Northside Hospital Cancer Institute, Atlanta, GA (United States); Spaans, J; Kumaraswamy, L; Podgorsak, M [Roswell Park Cancer Institute, Buffalo, NY (United States)

    2016-06-15

    Purpose: To quantify the effect of the Measurement Uncertainty function on planar dosimetry pass rates, as analyzed with Sun Nuclear Corporation analytic software (“MapCHECK” or “SNC Patient”). This optional function is toggled on by default upon software installation, and automatically increases the user-defined dose percent difference (%Diff) tolerance for each planar dose comparison. Methods: Dose planes from 109 IMRT fields and 40 VMAT arcs were measured with the MapCHECK 2 diode array, and compared to calculated planes from a commercial treatment planning system. Pass rates were calculated within the SNC analytic software using varying calculation parameters, including Measurement Uncertainty on and off. By varying the %Diff criterion for each dose comparison performed with Measurement Uncertainty turned off, an effective %Diff criterion was defined for each field/arc corresponding to the pass rate achieved with MapCHECK Uncertainty turned on. Results: For 3%/3mm analysis, the Measurement Uncertainty function increases the user-defined %Diff by 0.8–1.1% average, depending on plan type and calculation technique, for an average pass rate increase of 1.0–3.5% (maximum +8.7%). For 2%, 2 mm analysis, the Measurement Uncertainty function increases the user-defined %Diff by 0.7–1.2% average, for an average pass rate increase of 3.5–8.1% (maximum +14.2%). The largest increases in pass rate are generally seen with poorly-matched planar dose comparisons; the MapCHECK Uncertainty effect is markedly smaller as pass rates approach 100%. Conclusion: The Measurement Uncertainty function may substantially inflate planar dose comparison pass rates for typical IMRT and VMAT planes. The types of uncertainties incorporated into the function (and their associated quantitative estimates) as described in the software user’s manual may not accurately estimate realistic measurement uncertainty for the user’s measurement conditions. Pass rates listed in published

  11. Neighbourhood-consensus message passing and its potentials in image processing applications

    Science.gov (United States)

    Ružic, Tijana; Pižurica, Aleksandra; Philips, Wilfried

    2011-03-01

    In this paper, a novel algorithm for inference in Markov Random Fields (MRFs) is presented. Its goal is to find approximate maximum a posteriori estimates in a simple manner by combining neighbourhood influence of iterated conditional modes (ICM) and message passing of loopy belief propagation (LBP). We call the proposed method neighbourhood-consensus message passing because a single joint message is sent from the specified neighbourhood to the central node. The message, as a function of beliefs, represents the agreement of all nodes within the neighbourhood regarding the labels of the central node. This way we are able to overcome the disadvantages of reference algorithms, ICM and LBP. On one hand, more information is propagated in comparison with ICM, while on the other hand, the huge amount of pairwise interactions is avoided in comparison with LBP by working with neighbourhoods. The idea is related to the previously developed iterated conditional expectations algorithm. Here we revisit it and redefine it in a message passing framework in a more general form. The results on three different benchmarks demonstrate that the proposed technique can perform well both for binary and multi-label MRFs without any limitations on the model definition. Furthermore, it manifests improved performance over related techniques either in terms of quality and/or speed.

  12. Attaching transmitters to waterbirds using one versus two subcutaneous anchors: Retention and survival trade-offs

    Science.gov (United States)

    Lewis, Tyler; Esler, Daniel N.; Uher-Koch, Brian D.; Dickson, Rian D.; Anderson, Eric M.; Evenson, Joseph R.; Hupp, Jerry; Flint, Paul L.

    2017-01-01

    A major challenge of wildlife telemetry is choosing an attachment technique that maximizes transmitter retention while minimizing negative side effects. For waterbirds, attachment of transmitters with subcutaneous anchors has been an effective and well-established technique, having been used on >40 species. This method was recently modified to include a second subcutaneous anchor, presumably increasing transmitter retention beyond that of single-anchor attachments. This putative benefit may be offset, however, by increased health risks related to additional incisions and subcutaneous protrusions. To test this potential trade-off, we attached radiotransmitters to molting and wintering surf (Melanitta perspicillata) and white-winged scoters (M. fusca) during 2008 and 2009 in Washington State and southeast Alaska, USA, using single- (121 scoters) and double-anchor (128 scoters) attachment techniques. We estimated daily probabilities of survival and radio retention for each group, this being apparent retention for wintering scoters because we could not differentiate shed transmitters from flighted emigration. For scoters during the flightless remigial molt, we found that addition of a second anchor increased cumulative retention probability (±SE) over a 49-day period from 0.69 ± 0.11 for single-anchor to 0.88 ± 0.07 for double-anchor attachments, while having no effect on survival. However, during winter, scoters with double-anchor attachments experienced no improvement in apparent retention, while having significantly lower survival during their first 14 days following transmitter attachment; of 15 mortalities during this period, 11 had 2 subcutaneous anchors. From day 15 onward, winter survival rates were nearly identical for single- versus double-anchor attachments, indicating that adverse effects of subcutaneous anchors were mainly limited to the 14-day postattachment period. Overall, given that the survival cost of adding a second subcutaneous anchor

  13. Verification-Based Interval-Passing Algorithm for Compressed Sensing

    OpenAIRE

    Wu, Xiaofu; Yang, Zhen

    2013-01-01

    We propose a verification-based Interval-Passing (IP) algorithm for iteratively reconstruction of nonnegative sparse signals using parity check matrices of low-density parity check (LDPC) codes as measurement matrices. The proposed algorithm can be considered as an improved IP algorithm by further incorporation of the mechanism of verification algorithm. It is proved that the proposed algorithm performs always better than either the IP algorithm or the verification algorithm. Simulation resul...

  14. Efforts to reduce mortality to hydroelectric turbine-passed fish: locating and quantifying damaging shear stresses.

    Science.gov (United States)

    Cada, Glenn; Loar, James; Garrison, Laura; Fisher, Richard; Neitzel, Duane

    2006-06-01

    Severe fluid forces are believed to be a source of injury and mortality to fish that pass through hydroelectric turbines. A process is described by which laboratory bioassays, computational fluid dynamics models, and field studies can be integrated to evaluate the significance of fluid shear stresses that occur in a turbine. Areas containing potentially lethal shear stresses were identified near the stay vanes and wicket gates, runner, and in the draft tube of a large Kaplan turbine. However, under typical operating conditions, computational models estimated that these dangerous areas comprise less than 2% of the flow path through the modeled turbine. The predicted volumes of the damaging shear stress zones did not correlate well with observed fish mortality at a field installation of this turbine, which ranged from less than 1% to nearly 12%. Possible reasons for the poor correlation are discussed. Computational modeling is necessary to develop an understanding of the role of particular fish injury mechanisms, to compare their effects with those of other sources of injury, and to minimize the trial and error previously needed to mitigate those effects. The process we describe is being used to modify the design of hydroelectric turbines to improve fish passage survival.

  15. Survival rate of patients with differentiated thyroid cancer without early postoperative external radiation of the neck

    International Nuclear Information System (INIS)

    Saur, H.B.; Lerch, H.; Schober, O.

    1996-01-01

    Results of survival rates in differentiated thyroid carcinoma and comparison with a review of literature are given. Four hundred and sixty-four patients with differentiated cancer of the thyroid (354 female, 110 male, range: 6 to 84 years, median: 46.8 years; 275 patients with papillary and 190 with follicular cancer) were analyzed retrospectively. All patients were treated with ablative doses of radioiodine after thyroidectomy including compartment oriented lymphadenectomy in 27 patients. All patients passed an individual systematic follow-up according to risk: 'Low risk' pT≤3NxM0 vs. 'high risk' pT4 and/or M1. Early postoperative radiation was not included even in patients with local invasion (pT4). The corrected 5- and 10-year survival rates for papillary cancer are 0.91 and 0.91, for follicular cancer 0.94 resp. 0.78 (p=0.55), age (≤40 years 0.96 and 0.96, >40 years 0.90 and 0.80; p=0.008), gender (female 0.93 and 0.92, male 0.90 and 0.70; p=0.06) and invasion/distant metastases (pT4 and/or M1 0.83 and 0.71, other 0.97 and 0.97; p=0.0001). A systematic follow-up with an individually adapted standardized scheme is associated with high survival rates in patients with differentiated cancer of the thyroid. Early diagnosis of recurrences, locoregional lymph node and distant metastases with early surgical treatment including compartment oriented lymphadenectomy and radioiodine therapy yield high survival even without external radiation. (orig./MG) [de

  16. The experience of fatherhood following childhood cancer survival.

    Science.gov (United States)

    Agnew, Francis; Higgins, Aiveen; Casey, Maureen; McCarthy, Anthony

    2017-07-01

    This study explored the experience of becoming a father following childhood cancer survival. Semi-structured interviews were conducted with five fathers and analysed using interpretative phenomenological analysis. Three superordinate themes emerged: 'moving away from and revisiting the experience of cancer', 'making sense of fortune and loss following a life-threatening illness' and 'valuing the opportunity to be a father'. The transition to fatherhood brought unique and specific challenges to fathers. Nevertheless, all appeared to have positively adjusted to this transition. Findings recommended providing information and support to childhood survivors who wish to or who are about to become fathers.

  17. Outcomes, Approaches, and Challenges to Developing and Passing a Countywide Mandatory Vaccination Policy: St. Louis County’s Experience with Hepatitis A Vaccine for Food Service Personnel

    Directory of Open Access Journals (Sweden)

    Kristin D. Wilson

    2016-03-01

    Full Text Available In the early 1990s, St. Louis County had multiple foodservice worker-related hepatitis A outbreaks uncontrolled by standard outbreak interventions. Restaurant interest groups and the general public applied political pressure to local public health officials for more stringent interventions, including a mandatory vaccination policy. Local health departments can enact mandatory vaccination policies, but this has rarely been done. The study objectives were to describe the approach used to pass a mandatory vaccination policy at the local jurisdiction level and illustrate the outcome from this ordinance 15 years later. A case study design was used. In-depth, semi-structured interviews using guided questions were conducted in spring, 2015, with six key informants who had direct knowledge of the mandatory vaccination policy process. Meeting minutes and/or reports were also analyzed. A Poisson distribution analysis was used to calculate the rate of outbreaks before and after mandatory vaccination policy implementation. The policy appears to have reduced the number of hepatitis A outbreaks, lowering the morbidity and economic burden in St. Louis County. The lessons learned by local public health officials in passing a mandatory hepatitis A vaccination policy are important and relevant in today’s environment. The experience and lessons learned may assist other local health departments when faced with the potential need for mandatory policies for any vaccine preventable disease.

  18. Feasibility of a Modified E-PASS and POSSUM System for Postoperative Risk Assessment in Patients with Spinal Disease.

    Science.gov (United States)

    Chun, Dong Hyun; Kim, Do Young; Choi, Sun Kyu; Shin, Dong Ah; Ha, Yoon; Kim, Keung Nyun; Yoon, Do Heum; Yi, Seong

    2018-04-01

    This retrospective case control study aimed to evaluate the feasibility of using Estimation of Physiological Ability and Surgical Stress (E-PASS) and Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM) systems in patients undergoing spinal surgical procedures. Degenerative spine disease has increased in incidence in aging societies, as has the number of older adult patients undergoing spinal surgery. Many older adults are at a high surgical risk because of comorbidity and poor general health. We retrospectively reviewed 217 patients who had undergone spinal surgery at a single tertiary care. We investigated complications within 1 month after surgery. Criteria for both skin incision in E-PASS and operation magnitude in the POSSUM system were modified to fit spine surgery. We calculated the E-PASS and POSSUM scores for enrolled patients, and investigated the relationship between postoperative complications and both surgical risk scoring systems. To reinforce the predictive ability of the E-PASS system, we adjusted equations and developed modified E-PASS systems. The overall complication rate for spinal surgery was 22.6%. Forty-nine patients experienced 58 postoperative complications. Nineteen major complications, including hematoma, deep infection, pleural effusion, progression of weakness, pulmonary edema, esophageal injury, myocardial infarction, pneumonia, reoperation, renal failure, sepsis, and death, occurred in 17 patients. The area under the receiver operating characteristic curve (AUC) for predicted postoperative complications after spine surgery was 0.588 for E-PASS and 0.721 for POSSUM. For predicted major postoperative complications, the AUC increased to 0.619 for E-PASS and 0.842 for POSSUM. The AUC of the E-PASS system increased from 0.588 to 0.694 with the Modified E-PASS equation. The POSSUM system may be more useful than the E-PASS system for estimating postoperative surgical risk in patients undergoing

  19. An asymmetric MOSFET-C band-pass filter with on-chip charge pump auto-tuning

    International Nuclear Information System (INIS)

    Chen Fangxiong; Ma Heping; Jia Hailong; Shi Yin; Lin Min; Dai, Forster

    2009-01-01

    An asymmetric MOSFET-C band-pass filter (BPF) with on chip charge pump auto-tuning is presented. It is implemented in UMC (United Manufacturing Corporation) 0.18 μm CMOS process technology. The filter system with auto-tuning uses a master-slave technique for continuous tuning in which the charge pump outputs 2.663 V, much higher than the power supply voltage, to improve the linearity of the filter. The main filter with third order low-pass and second order high-pass properties is an asymmetric band-pass filter with bandwidth of 2.730-5.340 MHz. The in-band third order harmonic input intercept point (IIP3) is 16.621 dBm, with 50 Ω as the source impedance. The input referred noise is about 47.455 μV rms . The main filter dissipates 3.528 mW while the auto-tuning system dissipates 2.412 mW from a 1.8 V power supply. The filter with the auto-tuning system occupies 0.592 mm 2 and it can be utilized in GPS (global positioning system) and Bluetooth systems. (semiconductor integrated circuits)

  20. Relationship Between Physician Assistant Program Length and Physician Assistant National Certifying Examination Pass Rates.

    Science.gov (United States)

    Colletti, Thomas P; Salisbury, Helen; Hertelendy, Attila J; Tseng, Tina

    2016-03-01

    This study was conducted to examine the relationship between physician assistant (PA) educational program length and PA programs' 5-year average Physician Assistant National Certifying Examination (PANCE) first-time pass rates. This was a retrospective correlational study that analyzed previously collected data from a nonprobability purposive sample of accredited PA program Web sites. Master's level PA programs (n = 108) in the United States with published average PANCE scores for 5 consecutive classes were included. Provisional and probationary programs were excluded (n = 4). Study data were not normally distributed per the Kolmogorov-Smirnov test, P = .00. There was no relationship between program length and PANCE pass rates, ρ (108) = -0.04, P = .68. Further analyses examining a possible relationship between program phase length (didactic and clinical) and PANCE pass rates also demonstrated no differences (ρ [107] = -0.05, P = .60 and ρ [107] = 0.02, P = .80, respectively). The results of this study suggest that shorter length PA programs perform similarly to longer programs in preparing students to pass the PANCE. In light of rapid expansion of PA educational programs, educators may want to consider these findings when planning the length of study for new and established programs.

  1. Optimization of band-pass filtering parameters of a Raman lidar detecting atmospheric water vapor

    International Nuclear Information System (INIS)

    Cao, Kai-Fa; Hu, Shun-Xing; Wang, Ying-jian

    2012-01-01

    It is very important for daytime Raman lidar measurement of water vapor to determine the parameters of a band-pass filter, which are pertinent to the lidar signal to noise ratio (SNR). The simulated annealing (SA) algorithm method has an advantage in finding the extremum of a certain cost function. In this paper, the Raman spectrum of water vapor is simulated and then a first realization of a simulated annealing algorithm in the optimization of a band-pass filter of a Raman lidar system designed to detect daytime water vapor is presented. The simulated results indicate that the narrow band-pass filter has higher SNR than the wide filter does but there would be an increase in the temperature sensitivity of a narrowband Raman water vapor lidar in the upper troposphere. The numerical simulation indicates that the magnitude of the temperature dependent effect can reach 3.5% or more for narrow band-pass Raman water vapor measurements so it is necessary to consider a new water vapor Raman lidar equation that permits the temperature sensitivity of these equations to be confined to a single term. (paper)

  2. An asymmetric MOSFET-C band-pass filter with on-chip charge pump auto-tuning

    Energy Technology Data Exchange (ETDEWEB)

    Chen Fangxiong; Ma Heping; Jia Hailong; Shi Yin [Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China); Lin Min [Suzhou-CAS Semiconductors Integrated Technology Research Center, Suzhou 215021 (China); Dai, Forster, E-mail: fxchen@semi.ac.c [Department of Electrical and Computer Engineering, Auburn University, AL 36849 (United States)

    2009-08-15

    An asymmetric MOSFET-C band-pass filter (BPF) with on chip charge pump auto-tuning is presented. It is implemented in UMC (United Manufacturing Corporation) 0.18 {mu}m CMOS process technology. The filter system with auto-tuning uses a master-slave technique for continuous tuning in which the charge pump outputs 2.663 V, much higher than the power supply voltage, to improve the linearity of the filter. The main filter with third order low-pass and second order high-pass properties is an asymmetric band-pass filter with bandwidth of 2.730-5.340 MHz. The in-band third order harmonic input intercept point (IIP3) is 16.621 dBm, with 50 {Omega} as the source impedance. The input referred noise is about 47.455 {mu}V{sub rms}. The main filter dissipates 3.528 mW while the auto-tuning system dissipates 2.412 mW from a 1.8 V power supply. The filter with the auto-tuning system occupies 0.592 mm{sup 2} and it can be utilized in GPS (global positioning system) and Bluetooth systems. (semiconductor integrated circuits)

  3. PERSPECTIVE: Electrical activity enhances neuronal survival and regeneration

    Science.gov (United States)

    Corredor, Raul G.; Goldberg, Jeffrey L.

    2009-10-01

    The failure of regeneration in the central nervous system (CNS) remains an enormous scientific and clinical challenge. After injury or in degenerative diseases, neurons in the adult mammalian CNS fail to regrow their axons and reconnect with their normal targets, and furthermore the neurons frequently die and are not normally replaced. While significant progress has been made in understanding the molecular basis for this lack of regenerative ability, a second approach has gained momentum: replacing lost neurons or lost connections with artificial electrical circuits that interface with the nervous system. In the visual system, gene therapy-based 'optogenetics' prostheses represent a competing technology. Now, the two approaches are converging, as recent data suggest that electrical activity itself, via the molecular signaling pathways such activity stimulates, is sufficient to induce neuronal survival and regeneration, particularly in retinal ganglion cells. Here, we review these data, discuss the effects of electrical activity on neurons' molecular signaling pathways and propose specific mechanisms by which exogenous electrical activity may be acting to enhance survival and regeneration.

  4. Establishing Pass/Fail Criteria for Bronchoscopy Performance

    DEFF Research Database (Denmark)

    Konge, Lars; Clementsen, Paul; Larsen, Klaus Richter

    2012-01-01

    Background: Several tools have been created to assess competence in bronchoscopy. However, educational guidelines still use an arbitrary number of performed procedures to decide when basic competency is acquired. Objectives: The purpose of this study was to define pass/fail scores for two...... method. In the first we compared bronchoscopy performance scores of 14 novices with the scores of 14 experienced consultants to find the score that best discriminated between the two groups. In the second we asked an expert group of 7 experienced bronchoscopists to judge how a borderline trainee would...

  5. Survival in common cancers defined by risk and survival of family members

    Directory of Open Access Journals (Sweden)

    Jianguang Ji

    2011-10-01

    Full Text Available Studies on survival between familial and sporadic cancers have been inconclusive and only recent data on a limited number of cancers are available on the concordance of survival between family members. In this review, we address these questions by evaluating the published and unpublished data from the nation-wide Swedish Family-Cancer Database and a total of 13 cancer sites were assessed. Using sporadic cancer as reference, HRs were close to 1.0 for most of the familial cancers in both the offspring and parental generations, which suggested that survival in patients with familial and sporadic cancers was equal, with an exception for ovarian cancer with a worse prognosis. Compared to offspring whose parents had a poor survival, those with a good parental survival had a decreased risk of death for most cancers and HR was significantly decreased for cancers in the breast, prostate, bladder, and kidney. For colorectal and nervous system cancers, favorable survival between the generations showed a borderline significance. These data are consistent in showing that both good and poor survival in certain cancers aggregate in families. Genetic factors are likely to contribute to the results. These observations call for intensified efforts to consider heritability in survival as one mechanism regulating prognosis in cancer patients.

  6. Multiple-pass high-pressure homogenization of milk for the development of pasteurization-like processing conditions.

    Science.gov (United States)

    Ruiz-Espinosa, H; Amador-Espejo, G G; Barcenas-Pozos, M E; Angulo-Guerrero, J O; Garcia, H S; Welti-Chanes, J

    2013-02-01

    Multiple-pass ultrahigh pressure homogenization (UHPH) was used for reducing microbial population of both indigenous spoilage microflora in whole raw milk and a baroresistant pathogen (Staphylococcus aureus) inoculated in whole sterile milk to define pasteurization-like processing conditions. Response surface methodology was followed and multiple response optimization of UHPH operating pressure (OP) (100, 175, 250 MPa) and number of passes (N) (1-5) was conducted through overlaid contour plot analysis. Increasing OP and N had a significant effect (P pasteurization. Multiple-pass UHPH optimized conditions might help in producing safe milk without the detrimental effects associated with thermal pasteurization. © 2012 The Society for Applied Microbiology.

  7. First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota.

    Directory of Open Access Journals (Sweden)

    Richard Hansen

    Full Text Available Considerable effort has been made to categorise the bacterial composition of the human gut and correlate findings with gastrointestinal disease. The infant gut has long been considered sterile at birth followed by rapid colonisation; however, this view has recently been challenged. We examined first-pass meconium from healthy term infants to confirm or refute sterility.Healthy mothers were approached following vaginal delivery. First-pass meconium stools within 24 hours of delivery were obtained from healthy, breastfed infants with tight inclusion/exclusion criteria including rejecting any known antibiotic exposure - mother within 7 days preceding delivery or infant after birth. Stools were processed in triplicate for fluorescent in-situ hybridisation (FISH with 16S rRNA-targeted probes including Bifidobacterium; Bacteroides-Prevotella; Lactobacillaceae/Enterococcaceae; Enterobacteriaceae; Streptococcaceae; Staphylococcaceae and Enterococcaceae. Absolute counts of all bacteria and proportional identification of each bacterial group were calculated. Confirmation of bacterial presence by PCR was undertaken on FISH-positive samples.The mothers of 31 newborn infants were recruited, 15 met inclusion/exclusion criteria and provided a sample within 24 hours of birth, processed in the lab within 4 hours. All babies were 37-40 weeks gestation. 8/15 were male, mean birth weight was 3.4 kg and mean maternal age was 32 years. Meconium samples from 10/15 (66% infants had evidence of bacteria based on FISH analysis. Of these, PCR was positive in only 1. Positive FISH counts ranged from 2.2-41.8 x 10(4 cells/g with a mean of 15.4 x 10(4 cells/g. (The limit of detection for automated counting is 10(6 cells/g. Cell counts were too low to allow formal diversity analysis. Amplification by PCR was not possible despite positive spiked samples demonstrating the feasibility of reaction. One baby was dominated by Enterobacteriaceae. The others contained 2-5 genera

  8. Influence of membrane fatty acid composition and fluidity on airborne survival of Escherichia coli.

    Science.gov (United States)

    Ng, Tsz Wai; Chan, Wing Lam; Lai, Ka Man

    2018-04-01

    Finding ways to predict and control the survival of bacterial aerosols can contribute to the development of ways to alleviate a number of crucial microbiological problems. Significant damage in the membrane integrity of Escherichia coli during aerosolization and airborne suspension has been revealed which has prompted the question of how the membrane fatty acid composition and fluidity influence the survival of airborne bacteria. Two approaches of using isogenic mutants and different growth temperatures were selected to manipulate the membrane fatty acid composition of E. coli before challenging the bacteria with different relative humidity (RH) levels in an aerosol chamber. Among the mutants (fabR - , cfa. fadA - ), fabR - had the lowest membrane fluidity index (FI) and generally showed a higher survival than the parental strain. Surprisingly, its resistance to airborne stress was so strong that its viability was fully maintained even after airborne suspension at 40% RH, a harsh RH level to bacterial survival. Moreover, E. coli cultured at 20 °C with a higher FI than that at 30 and 37 °C generally had a lower survival after aerosolization and airborne suspension. Unlike FI, individual fatty acid and cyclopropane fatty acid composition did not relate to the bacterial survival. Lipid peroxidation of the membrane was undetected in all the bacteria. Membrane fluidity plays a stronger role in determining the bacteria survival during airborne suspension than during aerosolization. Certain relationships between FI and bacteria survival were identified, which could help predict the transmission of bacteria under different conditions.

  9. Enhancement effect of inter-pass annealing during equal channel angular pressing on grain refinement and ductility of 9Cr1Mo steel

    Energy Technology Data Exchange (ETDEWEB)

    Hao, Ting, E-mail: hao.ting@issp.ac.cn [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China); Tangi, Haiyin [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China); Luo, Guangnan [Institute of Plasma Physics, Chinese Academy of Sciences, P.O. Box 1126, Hefei 230031 (China); Wang, Xianping; Liu, Changsong [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China); Fang, Qianfeng, E-mail: qffang@issp.ac.cn [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China)

    2016-06-14

    To obtain enhanced mechanical property in both the strength and the ductility, 9Cr1Mo steel (T91) was severely deformed by equal channel angular pressing (ECAP) combined with an additional inter-pass annealing. Tensile results show that the additional inter-pass annealing can significantly improve the ductility (i.e. 18% of the total elongation after four-pass extrusion with the inter-pass annealing) but slightly decrease the tensile strength comparing with the case without the inter-pass annealing (i.e. 10% of the total elongation after four-pass ECAP processing). The average grain size of the two passes ECAP-processed materials with the inter-pass annealing (~0.8 µm) is smaller than that of the sample without inter-pass annealing (~2 µm), and the fraction of the high angle grain boundaries in the samples with the inter-pass annealing (~40%) is higher than that of ~34% (two-pass ECAP) without the inter-pass annealing based on electron backscattering diffraction analysis. The crystallite size and dislocation density were evaluated by means of the modified Williamson-Hall plot based on X-ray diffraction analysis. The microstructural analysis indicates that the enhanced ductility of the ECAP processed and inter-pass annealed materials can be attributed to the relatively smaller grain sizes, larger crystallite sizes and lower dislocation densities.

  10. Enhancement effect of inter-pass annealing during equal channel angular pressing on grain refinement and ductility of 9Cr1Mo steel

    International Nuclear Information System (INIS)

    Hao, Ting; Tangi, Haiyin; Luo, Guangnan; Wang, Xianping; Liu, Changsong; Fang, Qianfeng

    2016-01-01

    To obtain enhanced mechanical property in both the strength and the ductility, 9Cr1Mo steel (T91) was severely deformed by equal channel angular pressing (ECAP) combined with an additional inter-pass annealing. Tensile results show that the additional inter-pass annealing can significantly improve the ductility (i.e. 18% of the total elongation after four-pass extrusion with the inter-pass annealing) but slightly decrease the tensile strength comparing with the case without the inter-pass annealing (i.e. 10% of the total elongation after four-pass ECAP processing). The average grain size of the two passes ECAP-processed materials with the inter-pass annealing (~0.8 µm) is smaller than that of the sample without inter-pass annealing (~2 µm), and the fraction of the high angle grain boundaries in the samples with the inter-pass annealing (~40%) is higher than that of ~34% (two-pass ECAP) without the inter-pass annealing based on electron backscattering diffraction analysis. The crystallite size and dislocation density were evaluated by means of the modified Williamson-Hall plot based on X-ray diffraction analysis. The microstructural analysis indicates that the enhanced ductility of the ECAP processed and inter-pass annealed materials can be attributed to the relatively smaller grain sizes, larger crystallite sizes and lower dislocation densities.

  11. [Management abilities of the head surgeon: essential for survival!].

    Science.gov (United States)

    Jähne, J

    2012-04-01

    Due to increased economic challenges in the management of hospitals head surgeons do not only need excellent surgical expertise but also significant management qualities. The personality of head surgeons should include authenticity, sincerity, fairness and the ability to cooperate. Visionary leadership, strategic thinking and strategic management of the personnel are further prerequisites for success. Besides good abilities in communication head surgeons need knowledge of the operating figures for interpretation. To keep up with the own capabilities time and self-management is essential. A survival as head surgeon is likely if these qualities and abilities exist.

  12. A case of long term survival with skeletal only metastatic breast cancer.

    Science.gov (United States)

    Kuechle, Joseph B; McGrath, Brian E; Khoury, Thaer; Mindell, Eugene R

    2015-01-01

    The prognosis of patients with metastatic breast cancer is very poor. Because of this, treatment of skeletal metastasis is often palliative with limited goals rather than cure. However, there are those patients, such as presented here, who survive for an extended time. This thirty-six year old female presented with lytic lesions to one ulna and rib five years after mastectomy for breast cancer. Despite radiation and chemotherapy, the ulnar lesion expanded and resulted in an elbow dislocation. The rib lesion was resected and the arm amputated above the elbow. She developed local recurrence in both her above elbow amputation stump and chest wall and a more proximal below shoulder amputation was performed with resection of chest wall lesion. Even though she had locally aggressive disease, she has survived for 31 years after diagnosis without any evidence of disease. Reports of metastatic breast cancer survival indicate the five year survival to be 15%. There have been few reports indicating that those patients with skeletal only or oligometastatic disease have improved prognosis. It is not clear what biological properties of these tumors results in the improved survival. This case highlights the challenges of giving patients the optimal treatment in the light of limited ability to predict prognosis. It also highlights the need to further investigate the phenotypes of breast cancer that can, despite metastatic disease and with modern treatment go on to long survival. In addition this case demonstrates the importance of long term followup. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. PENN PASS: a program for graduates of foreign dental schools.

    Science.gov (United States)

    Berthold, P; Lopez, N

    1994-01-01

    An increasing number of graduates of foreign dental schools who enroll in advanced standing programs to qualify for licensure calls for dental schools to be prepared to handle not only the curricular demands but also the growing cultural diversity among its student population. The "reeducation" of this student group not only meets the need of foreign dentists for an American degree but may also provide health professionals to service various ethnic populations whose language and culture they are able to understand and identify with. A survey of students and graduates of a two-year Program for Advanced Standing Students (PASS) for graduates of foreign dental schools representing 34 countries aimed to arrive at an understanding of this student group through characterization of the foreign dentists and identification of their attitudes and feelings toward various aspects of the program, the school and faculty and their experience of stress. This report includes description of the distinctive features of the program which cater to specific needs and concerns of this non-traditional group of dental students. PASS students are accepted on the basis of their grades in dental school in home country, scores in the National Dental Board Examination Part I, Test of English as Foreign Language (TOEFL), and ratings in personal interviews. They complete an intensive summer program consisting of didactic and laboratory courses which prepares them for integration with four-year students for the last two years of didactic and clinical curriculum. Cultural diversity seminars, a special English class, PASS class meetings and seminars are unique additions to their program and aim to assist them adjust to the educational, social and cultural systems in an American school. Results of the survey show a majority of the PASS students feel that they are part of the school and that there is someone in the school whom they can approach for problems. An understanding of their ethnic and

  14. Stampi: a message passing library for distributed parallel computing. User's guide

    International Nuclear Information System (INIS)

    Imamura, Toshiyuki; Koide, Hiroshi; Takemiya, Hiroshi

    1998-11-01

    A new message passing library, Stampi, has been developed to realize a computation with different kind of parallel computers arbitrarily and making MPI (Message Passing Interface) as an unique interface for communication. Stampi is based on MPI2 specification. It realizes dynamic process creation to different machines and communication between spawned one within the scope of MPI semantics. Vender implemented MPI as a closed system in one parallel machine and did not support both functions; process creation and communication to external machines. Stampi supports both functions and enables us distributed parallel computing. Currently Stampi has been implemented on COMPACS (COMplex PArallel Computer System) introduced in CCSE, five parallel computers and one graphic workstation, and any communication on them can be processed on. (author)

  15. Passing the Turing Test Does Not Mean the End of Humanity.

    Science.gov (United States)

    Warwick, Kevin; Shah, Huma

    In this paper we look at the phenomenon that is the Turing test. We consider how Turing originally introduced his imitation game and discuss what this means in a practical scenario. Due to its popular appeal we also look into different representations of the test as indicated by numerous reviewers. The main emphasis here, however, is to consider what it actually means for a machine to pass the Turing test and what importance this has, if any. In particular does it mean that, as Turing put it, a machine can "think". Specifically we consider claims that passing the Turing test means that machines will have achieved human-like intelligence and as a consequence the singularity will be upon us in the blink of an eye.

  16. An Optimized Parallel FDTD Topology for Challenging Electromagnetic Simulations on Supercomputers

    Directory of Open Access Journals (Sweden)

    Shugang Jiang

    2015-01-01

    Full Text Available It may not be a challenge to run a Finite-Difference Time-Domain (FDTD code for electromagnetic simulations on a supercomputer with more than 10 thousands of CPU cores; however, to make FDTD code work with the highest efficiency is a challenge. In this paper, the performance of parallel FDTD is optimized through MPI (message passing interface virtual topology, based on which a communication model is established. The general rules of optimal topology are presented according to the model. The performance of the method is tested and analyzed on three high performance computing platforms with different architectures in China. Simulations including an airplane with a 700-wavelength wingspan, and a complex microstrip antenna array with nearly 2000 elements are performed very efficiently using a maximum of 10240 CPU cores.

  17. Relationship of residency program characteristics with pass rate of the American Board of Internal Medicine certifying exam

    Directory of Open Access Journals (Sweden)

    Amporn Atsawarungruangkit

    2015-09-01

    Full Text Available Objectives: To evaluate the relationship between the pass rate of the American Board of Internal Medicine (ABIM certifying exam and the characteristics of residency programs. Methods: The study used a retrospective, cross-sectional design with publicly available data from the ABIM and the Fellowship and Residency Electronic Interactive Database. All categorical residency programs with reported pass rates were included. Using univariate and multivariate, linear regression analyses, I analyzed how 69 factors (e.g., location, general information, number of faculty and trainees, work schedule, educational environment are related to the pass rate. Results: Of 371 programs, only one region had a significantly different pass rate from the other regions; however, as no other characteristics were reported in this region, I excluded program location from further analysis. In the multivariate analysis, pass rate was significantly associated with four program characteristics: ratio of full-time equivalent paid faculty to positions, percentage of osteopathic doctors, formal mentoring program, and on-site child care (OCC. Numerous factors were not associated at all, including minimum exam scores, salary, vacation days, and average hours per week. Conclusions: As shown through the ratio of full-time equivalent paid faculty to positions and whether there was a formal mentoring program, a highly supervised training experience was strongly associated with the pass rate. In contrast, percentage of osteopathic doctors was inversely related to the pass rate. Programs with OCC significantly outperformed programs without OCC. This study suggested that enhancing supervision of training programs and offering parental support may help attract and produce competitive residents.

  18. Stem cell death and survival in heart regeneration and repair.

    Science.gov (United States)

    Abdelwahid, Eltyeb; Kalvelyte, Audrone; Stulpinas, Aurimas; de Carvalho, Katherine Athayde Teixeira; Guarita-Souza, Luiz Cesar; Foldes, Gabor

    2016-03-01

    Cardiovascular diseases are major causes of mortality and morbidity. Cardiomyocyte apoptosis disrupts cardiac function and leads to cardiac decompensation and terminal heart failure. Delineating the regulatory signaling pathways that orchestrate cell survival in the heart has significant therapeutic implications. Cardiac tissue has limited capacity to regenerate and repair. Stem cell therapy is a successful approach for repairing and regenerating ischemic cardiac tissue; however, transplanted cells display very high death percentage, a problem that affects success of tissue regeneration. Stem cells display multipotency or pluripotency and undergo self-renewal, however these events are negatively influenced by upregulation of cell death machinery that induces the significant decrease in survival and differentiation signals upon cardiovascular injury. While efforts to identify cell types and molecular pathways that promote cardiac tissue regeneration have been productive, studies that focus on blocking the extensive cell death after transplantation are limited. The control of cell death includes multiple networks rather than one crucial pathway, which underlies the challenge of identifying the interaction between various cellular and biochemical components. This review is aimed at exploiting the molecular mechanisms by which stem cells resist death signals to develop into mature and healthy cardiac cells. Specifically, we focus on a number of factors that control death and survival of stem cells upon transplantation and ultimately affect cardiac regeneration. We also discuss potential survival enhancing strategies and how they could be meaningful in the design of targeted therapies that improve cardiac function.

  19. A nomogram to predict the probability of passing the American Board of Internal Medicine examination

    Directory of Open Access Journals (Sweden)

    Andrei Brateanu

    2012-10-01

    Full Text Available Background : Although the American Board of Internal Medicine (ABIM certification is valued as a reflection of physicians’ experience, education, and expertise, limited methods exist to predict performance in the examination. Purpose : The objective of this study was to develop and validate a predictive tool based on variables common to all residency programs, regarding the probability of an internal medicine graduate passing the ABIM certification examination. Methods : The development cohort was obtained from the files of the Cleveland Clinic internal medicine residents who began training between 2004 and 2008. A multivariable logistic regression model was built to predict the ABIM passing rate. The model was represented as a nomogram, which was internally validated with bootstrap resamples. The external validation was done retrospectively on a cohort of residents who graduated from two other independent internal medicine residency programs between 2007 and 2011. Results : Of the 194 Cleveland Clinic graduates used for the nomogram development, 175 (90.2% successfully passed the ABIM certification examination. The final nomogram included four predictors: In-Training Examination (ITE scores in postgraduate year (PGY 1, 2, and 3, and the number of months of overnight calls in the last 6 months of residency. The nomogram achieved a concordance index (CI of 0.98 after correcting for over-fitting bias and allowed for the determination of an estimated probability of passing the ABIM exam. Of the 126 graduates from two other residency programs used for external validation, 116 (92.1% passed the ABIM examination. The nomogram CI in the external validation cohort was 0.94, suggesting outstanding discrimination. Conclusions : A simple user-friendly predictive tool, based on readily available data, was developed to predict the probability of passing the ABIM exam for internal medicine residents. This may guide program directors’ decision

  20. Survival-related profile, pathways, and transcription factors in ovarian cancer.

    Directory of Open Access Journals (Sweden)

    Anne P G Crijns

    2009-02-01

    Full Text Available BACKGROUND: Ovarian cancer has a poor prognosis due to advanced stage at presentation and either intrinsic or acquired resistance to classic cytotoxic drugs such as platinum and taxoids. Recent large clinical trials with different combinations and sequences of classic cytotoxic drugs indicate that further significant improvement in prognosis by this type of drugs is not to be expected. Currently a large number of drugs, targeting dysregulated molecular pathways in cancer cells have been developed and are introduced in the clinic. A major challenge is to identify those patients who will benefit from drugs targeting these specific dysregulated pathways.The aims of our study were (1 to develop a gene expression profile associated with overall survival in advanced stage serous ovarian cancer, (2 to assess the association of pathways and transcription factors with overall survival, and (3 to validate our identified profile and pathways/transcription factors in an independent set of ovarian cancers. METHODS AND FINDINGS: According to a randomized design, profiling of 157 advanced stage serous ovarian cancers was performed in duplicate using approximately 35,000 70-mer oligonucleotide microarrays. A continuous predictor of overall survival was built taking into account well-known issues in microarray analysis, such as multiple testing and overfitting. A functional class scoring analysis was utilized to assess pathways/transcription factors for their association with overall survival. The prognostic value of genes that constitute our overall survival profile was validated on a fully independent, publicly available dataset of 118 well-defined primary serous ovarian cancers. Furthermore, functional class scoring analysis was also performed on this independent dataset to assess the similarities with results from our own dataset. An 86-gene overall survival profile discriminated between patients with unfavorable and favorable prognosis (median survival, 19

  1. Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity

    International Nuclear Information System (INIS)

    Kim, Jeong Hun; Kim, Jin Hyoung; Yu, Young Suk; Kim, Kyu-Won; Kim, Myung Hun

    2009-01-01

    The retina maintains homeostasis through the blood-retinal barrier (BRB). Although it is ideal to deliver the drug to the retina via systemic administration, it is still challenging due to the BRB strictly regulating permeation from blood to the retina. Herein, we demonstrated that intravenously administered gold nanoparticles could pass through the BRB and are distributed in all retinal layers without cytotoxicity. After intravenous injection of gold nanoparticles into C57BL/6 mice, 100 nm nanoparticles were not detected in the retina whereas 20 nm nanoparticles passed through the BRB and were distributed in all retinal layers. 20 nm nanoparticles in the retina were observed in neurons (75 ± 5%), endothelial cells (17 ± 6%) and peri-endothelial glial cells (8 ± 3%), where nanoparticles were bound on the membrane. In the retina, cells containing nanoparticles did not show any structural abnormality and increase of cell death compared to cells without nanoparticles. Gold nanoparticles never affected the viability of retinal endothelial cells, astrocytes and retinoblastoma cells. Furthermore, gold nanoparticles never led to any change in expression of representative biological molecules including zonula occludens-1 and glut-1 in retinal endothelial cells, neurofilaments in differentiated retinoblastoma cells and glial fibrillary acidic protein in astrocytes. Therefore, our data suggests that small gold nanoparticles (20 nm) could be an alternative for drug delivery across the BRB, which could be safely applied in vivo.

  2. Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong Hun; Kim, Jin Hyoung; Yu, Young Suk [Department of Ophthalmology, Seoul National University College of Medicine and Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital, Seoul 151744 (Korea, Republic of); Kim, Kyu-Won [NeuroVascular Coordination Research Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151742 (Korea, Republic of); Kim, Myung Hun, E-mail: hunin315@paran.com, E-mail: ysyu@snu.ac.kr [Department of Chemistry, Yonsei University, 134 Shinchon-dong, Seodaemun-ku, Seoul 120749 (Korea, Republic of)

    2009-12-16

    The retina maintains homeostasis through the blood-retinal barrier (BRB). Although it is ideal to deliver the drug to the retina via systemic administration, it is still challenging due to the BRB strictly regulating permeation from blood to the retina. Herein, we demonstrated that intravenously administered gold nanoparticles could pass through the BRB and are distributed in all retinal layers without cytotoxicity. After intravenous injection of gold nanoparticles into C57BL/6 mice, 100 nm nanoparticles were not detected in the retina whereas 20 nm nanoparticles passed through the BRB and were distributed in all retinal layers. 20 nm nanoparticles in the retina were observed in neurons (75 {+-} 5%), endothelial cells (17 {+-} 6%) and peri-endothelial glial cells (8 {+-} 3%), where nanoparticles were bound on the membrane. In the retina, cells containing nanoparticles did not show any structural abnormality and increase of cell death compared to cells without nanoparticles. Gold nanoparticles never affected the viability of retinal endothelial cells, astrocytes and retinoblastoma cells. Furthermore, gold nanoparticles never led to any change in expression of representative biological molecules including zonula occludens-1 and glut-1 in retinal endothelial cells, neurofilaments in differentiated retinoblastoma cells and glial fibrillary acidic protein in astrocytes. Therefore, our data suggests that small gold nanoparticles (20 nm) could be an alternative for drug delivery across the BRB, which could be safely applied in vivo.

  3. Failure probabilities of SiC clad fuel during a LOCA in public acceptable simple SMR (PASS)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Youho, E-mail: euo@kaist.ac.kr; Kim, Ho Sik, E-mail: hskim25@kaist.ac.kr; NO, Hee Cheon, E-mail: hcno@kaist.ac.kr

    2015-10-15

    Highlights: • Graceful operating conditions of SMRs markedly lower SiC cladding stress. • Steady-state fracture probabilities of SiC cladding is below 10{sup −7} in SMRs. • PASS demonstrates fuel coolability (T < 1300 °C) with sole radiation in LOCA. • SiC cladding failure probabilities of PASS are ∼10{sup −2} in LOCA. • Cold gas gap pressure controls SiC cladding tensile stress level in LOCA. - Abstract: Structural integrity of SiC clad fuels in reference Small Modular Reactors (SMRs) (NuScale, SMART, IRIS) and a commercial pressurized water reactor (PWR) are assessed with a multi-layered SiC cladding structural analysis code. Featured with low fuel pin power and temperature, SMRs demonstrate markedly reduced incore-residence fracture probabilities below ∼10{sup −7}, compared to those of commercial PWRs ∼10{sup −6}–10{sup −1}. This demonstrates that SMRs can serve as a near-term deployment fit to SiC cladding with a sound management of its statistical brittle fracture. We proposed a novel SMR named Public Acceptable Simple SMR (PASS), which is featured with 14 × 14 assemblies of SiC clad fuels arranged in a square ring layout. PASS aims to rely on radiative cooling of fuel rods during a loss of coolant accident (LOCA) by fully leveraging high temperature tolerance of SiC cladding. An overarching assessment of SiC clad fuel performance in PASS was conducted with a combined methodology—(1) FRAPCON-SiC for steady-state performance analysis of PASS fuel rods, (2) computational fluid dynamics code FLUENT for radiative cooling rate of fuel rods during a LOCA, and (3) multi-layered SiC cladding structural analysis code with previously developed SiC recession correlations under steam environments for both steady-state and LOCA. The results show that PASS simultaneously maintains desirable fuel cooling rate with the sole radiation and sound structural integrity of fuel rods for over 36 days of a LOCA without water supply. The stress level of

  4. Microstructural and mechanical responses to various rolling speeds determined in multi-pass break-down rolling of AZ31B alloy

    Science.gov (United States)

    Jia, Weitao; Tang, Yan; Ning, Fangkun; Le, Qichi; Cui, Jianzhong

    2018-04-01

    Different rolling operations of as-cast AZ31B alloy were performed under different rolling speed (18 ∼ 72 m min‑1) and rolling pass conditions at 400 °C. Microstructural studies, tensile testing and formability evaluation relevant to each rolling operation were investigated. For 1-pass rolling, coarse average grain size (CAGS) region gradually approached the center layer as the rolling speed increased. Moreover, twins, shear bands and coarse-grain structures were the dominant components in the microstructure of plates rolled at 18, 48 and 72 m min‑1, respectively, indicating the severe deformation inhomogeneity under the high reduction per pass condition. For 2-pass rolling and 4-pass rolling, dynamic recrystallization was observed to be well and CAGS region has substantially disappeared, indicating the significant improvement in deformation uniformity and further the grain homogenization under the conditions. Microstructure uniformity degree of 2-pass rolled plates did not vary much as the rolling speed varied. On this basis, shear band distribution dominated the deformation behavior during the uniaxial tension of the 2-pass rolled plates. However, microstructure uniformity accompanied by twin distribution played a leading role in stretching the 4-pass rolled plates.

  5. A message passing algorithm for the evaluation of social influence

    NARCIS (Netherlands)

    Vassio, Luca; Fagnani, Fabio; Frasca, Paolo; Ozdaglar, Asuman

    2014-01-01

    In this paper, we define a new measure of node centrality in social networks, the Harmonic Influence Centrality, which emerges naturally in the study of social influence over networks. Next, we introduce a distributed message passing algorithm to compute the Harmonic Influence Centrality of each

  6. Buffels (Wes), Elsies, Sir Lowry's pass, Steenbras and Buffels (Oos)

    CSIR Research Space (South Africa)

    Heinecken, TJE

    1982-06-01

    Full Text Available This report is a synthesis of all available information on five of the smaller rivers discharging in to False bay combined as a single volume. The rivers dealt with are the Buffels (Wes), Elsies, Sir Lowry' Pass, Steenbras and Buffels (Oos). False...

  7. An efficient communication scheme for solving Sn equations on message-passing multiprocessors

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1993-01-01

    Early models of Intel's hypercube multiprocessors, e.g., the iPSC/1 and iPSC/2, were characterized by the high latency of message passing. This relatively weak dependence of the communication penalty on the size of messages, in contrast to its strong dependence on the number of messages, justified using the Fan-in Fan-out algorithm (which implements a minimum spanning tree path) to perform global operations, such as global sums, etc. Recent models of message-passing computers, such as the iPSC/860 and the Paragon, have been found to possess much smaller latency, thus forcing a reexamination of the issue of performance optimization with respect to communication schemes. Essentially, the Fan-in Fan-out scheme minimizes the number of nonsimultaneous messages sent but not the volume of data traffic across the network. Furthermore, if a global operation is performed in conjunction with the message passing, a large fraction of the attached nodes remains idle as the number of utilized processors is halved in each step of the process. On the other hand, the Recursive Halving scheme offers the smallest communication cost for global operations but has some drawbacks

  8. 17Beta-estradiol affects the response of complement components and survival of rainbow trout (Oncorhynchus mykiss) challenged by bacterial infection.

    Science.gov (United States)

    Wenger, Michael; Sattler, Ursula; Goldschmidt-Clermont, Elinor; Segner, Helmut

    2011-07-01

    Research on the endocrine role of estrogens has focused on the reproductive system, while other potential target systems have been less studied. Here, we investigated the possible immunomodulating role of 17β-estradiol (E2) using rainbow trout (Oncorhynchus mykiss) as a model. The aims of the study were to examine a) whether estrogens can modulate immune gene transcription levels, and b) whether this has functional implications for the resistance of trout towards pathogens. Trout were reared from fertilization until 6 months of age under (1) control conditions, (2) short-term E2-treatment (6-month-old juveniles were fed a diet containing 20 mg E2/kg for 2 weeks), or c) long-term E2-treatment (twice a 2-h-bath-exposure of trout embryos to 400 μg 17β-estradiol (E2)/L, followed by rearing on the E2-spiked diet from start-feeding until 6 months of age). Analysis of plasma estrogen levels indicated that the internal estrogen concentrations of E2-exposed fish were within the physiological range and analysis of hepatic vitellogenin mRNA levels indicated that the E2 administration was effective in activating the endogenous estrogen receptor pathway. However, expression levels of the hepatic complement components C3-1, C3-3, and Factor H were not affected by E2-treatment. In a next step, 6-month-old juveniles were challenged with pathogenic bacteria (Yersinia ruckeri). In control fish, this bacterial infection resulted in significant up-regulation of the mRNA levels of hepatic complement genes (C3-1, C3-3, Factor B, Factor H), while E2-treated fish showed no or significantly lower up-regulation of the complement gene transcription levels. Apparently, the E2-treated trout had a lower capacity to activate their immune system to defend against the bacterial infection. This interpretation is corroborated by the finding that survival of E2-treated fish under bacterial challenge was significantly lower than in the control group. In conclusion, the results from this study

  9. Assessing survival of Mid-Columbia River released juvenile salmonids at McNary Dam, Washington, 2008-09

    Science.gov (United States)

    Evans, Scott D.; Walker, Christopher E.; Brewer, Scott J.; Adams, Noah S.

    2010-01-01

    little information is available about their survival as they pass hydroelectric dams in the lower Columbia River. Collecting information on fish released in the Mid-Columbia River, as well as on fish released 8 kilometers upstream of McNary Dam, allowed us to evaluate similarities and differences in passage and survival probabilities. In general, juvenile salmonids released in the Mid-Columbia River and detected at and downstream of McNary Dam showed trends in passage and survival probabilities that were similar to fish released 8 kilometers upstream of McNary Dam. This suggests that increased migration time or length of migration had little effect on behavior and survival of Mid-Columbia River released juvenile salmonids detected at McNary Dam.

  10. A Two-Pass Exact Algorithm for Selection on Parallel Disk Systems.

    Science.gov (United States)

    Mi, Tian; Rajasekaran, Sanguthevar

    2013-07-01

    Numerous OLAP queries process selection operations of "top N", median, "top 5%", in data warehousing applications. Selection is a well-studied problem that has numerous applications in the management of data and databases since, typically, any complex data query can be reduced to a series of basic operations such as sorting and selection. The parallel selection has also become an important fundamental operation, especially after parallel databases were introduced. In this paper, we present a deterministic algorithm Recursive Sampling Selection (RSS) to solve the exact out-of-core selection problem, which we show needs no more than (2 + ε ) passes ( ε being a very small fraction). We have compared our RSS algorithm with two other algorithms in the literature, namely, the Deterministic Sampling Selection and QuickSelect on the Parallel Disks Systems. Our analysis shows that DSS is a (2 + ε )-pass algorithm when the total number of input elements N is a polynomial in the memory size M (i.e., N = M c for some constant c ). While, our proposed algorithm RSS runs in (2 + ε ) passes without any assumptions. Experimental results indicate that both RSS and DSS outperform QuickSelect on the Parallel Disks Systems. Especially, the proposed algorithm RSS is more scalable and robust to handle big data when the input size is far greater than the core memory size, including the case of N ≫ M c .

  11. Device Performance Improvement of Double-Pass Wire Mesh Packed Solar Air Heaters under Recycling Operation Conditions

    Directory of Open Access Journals (Sweden)

    Chii-Dong Ho

    2016-01-01

    Full Text Available The improvement of device performance of a recycling solar air heater featuring a wire mesh packing was investigated experimentally and theoretically. The application of the wire mesh packing and recycle-effect concept to the present study were proposed aiming to strengthen the convective heat-transfer coefficient due to increased turbulence. Comparisons were made among different designs, including the single-pass, flat-plate double-pass and recycling double-pass wire mesh packed operations. The collector efficiency of the recycling double-pass wire mesh packed solar air heater was much higher than that of the other configurations for various recycle ratios and mass flow rates scenarios. The power consumption increment due to implementing wire mesh in solar air heaters was also discussed considering the economic feasibility. A fairly good agreement between theoretical predictions and experimental measurements was achieved with an analyzed error of 1.07%–9.32%.

  12. The utility of first-pass perfusion CT in hyperacute ischemic stroke: early experience

    International Nuclear Information System (INIS)

    Lee, Tae Jin; Lee, Myeong Sub; Kim, Myung Soon; Hong, In Soo; Lee, Young Han; Lee, Ji Yong; Whang, Kum

    2003-01-01

    To evaluate the findings of first-pass perfusion CT in hyperacute stroke patients and to determine the relationship between a perfusion map and final infarct outcome. Thirty-five patients admitted with ischemic stroke within six hours of the onset of symptoms underwent conventional cerebral CT immediately followed by first-pass perfusion CT. Nineteen underwent follow-up CT or MRI, and three types of dynamic perfusion map-cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) - were evaluated by two radiologists. In these 19 patients, initial perfusion maps correlated with final infarct size, determined during follow-up studies. In all 35 patients, major large vessel perfusion abnormalities [middle cerebral artery - MCA MCA and anterior cerebral artery - ACA (n=2); posterior cerebral artery - PCA (n=8)] were detected. On first-pass perfusion maps depicting CBF and MTT, all lesions were detected, and CBF and delayed MTT values were recorded. CBV maps showed variable findings. In all 19 patients who were followed up, the final infarct size of perfusion abnormalities was less than that depicted on CBF and MTT maps, and similar to or much greater than that seen on CBV maps. First-pass perfusion CT scanning is a practical, rapid and advanced imaging technique. In hyperacute stroke patients, it provides important and reliable hemodynamic information as to which brain tissue is salvageable by thrombolytic therapy, and predicts outcome of such treatment

  13. Survival Estimates for the Passage of Spring-Migrating Juvenile Salmonids through Snake and Columbia River Dams and Reservoirs, 2001-2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Zabel, Richard; Williams, John G.; Smith, Steven G. (Northwest and Alaska Fisheries Science Center, Fish Ecology Division, Seattle, WA)

    2002-06-01

    In 2001, the National Marine Fisheries Service and the University of Washington completed the ninth year of a study to estimate survival and travel time of juvenile salmonids (Oncorhynchus spp.) passing through dams and reservoirs on the Snake and Columbia Rivers. All estimates were derived from passive integrated transponder (PIT)-tagged fish. We PIT tagged and released at Lower Granite Dam a total of 17,028 hatchery and 3,550 wild steelhead. In addition, we utilized fish PIT tagged by other agencies at traps and hatcheries upstream of the hydropower system and sites within the hydropower system. PIT-tagged smolts were detected at interrogation facilities at Lower Granite, Little Goose, Lower Monumental, McNary, John Day, and Bonneville Dams and in the PIT-tag detector trawl operated in the Columbia River estuary. Survival estimates were calculated using the Single-Release Model. Primary research objectives in 2001 were to: (1) estimate reach and project survival and travel time in the Snake and Columbia Rivers throughout the yearling chinook salmon and steelhead migrations; (2) evaluate relationships between survival estimates and migration conditions; and (3) evaluate the survival-estimation models under prevailing conditions. This report provides reach survival and travel time estimates for 2001 for PIT-tagged yearling chinook salmon and steelhead (hatchery and wild) in the Snake and Columbia Rivers. Results are reported primarily in the form of tables and figures with a minimum of text. More details on methodology and statistical models used are provided in previous reports cited in the text. Results for summer-migrating chinook salmon will be reported separately.

  14. Promotion and co-ordination in Switzerland within the framework of the EU Motor Challenge Program - Final report; Promotion und Koordination in der Schweiz zum Motor Challenge Programm der EU - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Nipkow, J. [Arena, Zuerich (Switzerland); Tanner, R. [Semafor, Basel (Switzerland); Gloor, R. [Gloor Engineering, Sufers (Switzerland)

    2008-07-01

    The goal of the Motor Challenge Promotion project was to establish information on the European Motor Challenge Programme to users of electric motor driven systems, and to encourage them to start activities on energy efficient drives in their plants and sites. The promotion project served also as National Contact Point of the European Motor Challenge Programme in Switzerland and coordinated information transfer of national activities on drives efficiency. Dissemination of Motor Challenge information and know-how was achieved mainly by these means: Internet (www.motorchallenge.ch), electronic newsletter twice a year, articles in technical publications, presentations at events on energy efficiency and in training courses at technical universities. Communication with the EU-Motor Challenge Programme was provided by e-mail exchange and by attending conferences and workshops, e.g. EEMODS 2005 (Heidelberg), Motor Challenge Workshop 2007 (Paris). Queries and the attendance at information events showed a growing interest in efficiency of electric drives. The Swiss Motor Challenge team was involved in the preparation of the SwissEnergy implementation programme on drives efficiency. The Swiss agency for efficient energy use S.A.F.E. launched the programme named 'Topmotors' in autumn 2007. The Motor Challenge activities will pass over to Topmotors; the web site will be linked to www.topmotors.ch and a Topmotors newsletter will be launched. (author)

  15. Axillary lymph node core biopsy for breast cancer metastases — How many needle passes are enough?

    International Nuclear Information System (INIS)

    Macaskill, E.J.; Purdie, C.A.; Jordan, L.B.; Mclean, D.; Whelehan, P.; Brown, D.C.; Evans, A.

    2012-01-01

    Aim: To determine the diagnostic yield of each of three core passes when sampling abnormal lymph nodes in patients presenting with breast cancer. Materials and methods: All patients suspected of having breast cancer had axillary ultrasound as part of initial assessment. Radiologically abnormal nodes (cortical thickness >2.3 mm or round shape) were biopsied with three passes of a 22 mm throw 14 G core biopsy needle and sent for histopathology in separate numbered pots. Data were collected prospectively, and analysis performed on the data of 55 consecutive patients who had positive nodes on at least one core biopsy needle pass. Results: Of 55 patients with a positive node on core biopsy, tumour was noted in all three cores taken in 39 (70.9%). Lymph node metastasis was detected in 45 (81.8%) first core biopsies. With the first two cores taken, positive results were detected in 53 of 55 cases (96.4%). In both cases where tumour was only found on a third core biopsy pass, no lymph node tissue was present in the first two biopsy passes. Conclusion: Two well-directed 14 G core biopsy samples from an abnormal axillary node are adequate for diagnosis of breast cancer metastasis.

  16. Efficient design of FIR filter based low-pass differentiators for biomedical signal processing

    Directory of Open Access Journals (Sweden)

    Wulf Michael

    2016-09-01

    Full Text Available This paper describes an alternative design of linear phase low-pass differentiators with a finite impulse response (type III FIR filter. To reduce the number of necessary filter coefficients, the differentiator’s transfer function is approximated by a Fourier series of a triangle function. Thereby the filter’s transition steepness towards the stopband is intentionally reduced. It can be shown that the proposed design of low-pass differentiators yields to similar results as other published design recommendations, while the filter order can be significantly reduced.

  17. Single Pass Collider Memo: Gradient Perturbations of the SLC arc

    Energy Technology Data Exchange (ETDEWEB)

    Weng, W.T.; Sands, M.; /SLAC

    2016-12-16

    As the beam passes through the arcs, the gradient it encounters at each magnet differs from the design value. This deviation may be in part random and in part systematic. In this note we make estimates of the effects to be expected from both kinds of errors.

  18. Multinationals and plant survival

    DEFF Research Database (Denmark)

    Bandick, Roger

    2010-01-01

    The aim of this paper is twofold: first, to investigate how different ownership structures affect plant survival, and second, to analyze how the presence of foreign multinational enterprises (MNEs) affects domestic plants’ survival. Using a unique and detailed data set on the Swedish manufacturing...... sector, I am able to separate plants into those owned by foreign MNEs, domestic MNEs, exporting non-MNEs, and purely domestic firms. In line with previous findings, the result, when conditioned on other factors affecting survival, shows that foreign MNE plants have lower survival rates than non......-MNE plants. However, separating the non-MNEs into exporters and non-exporters, the result shows that foreign MNE plants have higher survival rates than non-exporting non-MNEs, while the survival rates of foreign MNE plants and exporting non-MNE plants do not seem to differ. Moreover, the simple non...

  19. Belief propagation decoding of quantum channels by passing quantum messages

    International Nuclear Information System (INIS)

    Renes, Joseph M

    2017-01-01

    The belief propagation (BP) algorithm is a powerful tool in a wide range of disciplines from statistical physics to machine learning to computational biology, and is ubiquitous in decoding classical error-correcting codes. The algorithm works by passing messages between nodes of the factor graph associated with the code and enables efficient decoding of the channel, in some cases even up to the Shannon capacity. Here we construct the first BP algorithm which passes quantum messages on the factor graph and is capable of decoding the classical–quantum channel with pure state outputs. This gives explicit decoding circuits whose number of gates is quadratic in the code length. We also show that this decoder can be modified to work with polar codes for the pure state channel and as part of a decoder for transmitting quantum information over the amplitude damping channel. These represent the first explicit capacity-achieving decoders for non-Pauli channels. (fast track communication)

  20. Belief propagation decoding of quantum channels by passing quantum messages

    Science.gov (United States)

    Renes, Joseph M.

    2017-07-01

    The belief propagation (BP) algorithm is a powerful tool in a wide range of disciplines from statistical physics to machine learning to computational biology, and is ubiquitous in decoding classical error-correcting codes. The algorithm works by passing messages between nodes of the factor graph associated with the code and enables efficient decoding of the channel, in some cases even up to the Shannon capacity. Here we construct the first BP algorithm which passes quantum messages on the factor graph and is capable of decoding the classical-quantum channel with pure state outputs. This gives explicit decoding circuits whose number of gates is quadratic in the code length. We also show that this decoder can be modified to work with polar codes for the pure state channel and as part of a decoder for transmitting quantum information over the amplitude damping channel. These represent the first explicit capacity-achieving decoders for non-Pauli channels.

  1. Policy Analysis Screening System (PASS) demonstration: sample queries and terminal instructions

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-10-16

    This document contains the input and output for the Policy Analysis Screening System (PASS) demonstration. This demonstration is stored on a portable disk at the Environmental Impacts Division. Sample queries presented here include: (1) how to use PASS; (2) estimated 1995 energy consumption from Mid-Range Energy-Forecasting System (MEFS) data base; (3) pollution projections from Strategic Environmental Assessment System (SEAS) data base; (4) diesel auto regulations; (5) diesel auto health effects; (6) oil shale health and safety measures; (7) water pollution effects of SRC; (8) acid rainfall from Energy Environmental Statistics (EES) data base; 1990 EIA electric generation by fuel type; sulfate concentrations by Federal region; forecast of 1995 SO/sub 2/ emissions in Region III; and estimated electrical generating capacity in California to 1990. The file name for each query is included.

  2. Duration of senescent cell survival in vitro as a characteristic of organism longevity, an additional to the proliferative potential of fibroblasts.

    Science.gov (United States)

    Yegorov, Yegor E; Zelenin, Alexander V

    2003-04-24

    More than 40 years have passed since the original publication by Hayflick and Moorhead led to the concept of the 'Hayflick limit' of the maximum number of divisions which somatic cells undergo in vitro. This concept is still regarded as a fundamental characteristic of species longevity. Here we want to emphasize another characteristic of somatic cells, namely, the duration of their survival in vitro in the non-dividing state after cessation of proliferation. This is suggested on the basis of results of recent experiments with so-called Japanese accelerated senescent mice. Results of these experiments reveal a good correlation between the longevity of the mice, the number of duplications of their fibroblasts in vitro, and the survival time of these cells in the non-dividing state. In routine culture conditions, cell survival time may be very long, as much as a few years. However, when the cells are grown under conditions of oxidative stress, cellular longevity is markedly shortened. This new test may serve as an additional marker of organismic longevity. The comparative value of both tests, the classical 'Hayflick limit' and the new test, is discussed.

  3. Effects of the I-PASS Nursing Handoff Bundle on communication quality and workflow.

    Science.gov (United States)

    Starmer, Amy J; Schnock, Kumiko O; Lyons, Aimee; Hehn, Rebecca S; Graham, Dionne A; Keohane, Carol; Landrigan, Christopher P

    2017-12-01

    Handoff communication errors are a leading source of sentinel events. We sought to determine the impact of a handoff improvement programme for nurses. We conducted a prospective pre-post intervention study on a paediatric intensive care unit in 2011-2012. The I-PASS Nursing Handoff Bundle intervention consisted of educational training, verbal handoff I-PASS mnemonic implementation, and visual materials to provide reinforcement and sustainability. We developed handoff direct observation and time motion workflow assessment tools to measure: (1) quality of the verbal handoff, including interruption frequency and presence of key handoff data elements; and (2) duration of handoff and other workflow activities. I-PASS implementation was associated with improvements in verbal handoff communications, including inclusion of illness severity assessment (37% preintervention vs 67% postintervention, p=0.001), patient summary (81% vs 95%, p=0.05), to do list (35% vs 100%, p<0.001) and an opportunity for the receiving nurse to ask questions (34% vs 73%, p<0.001). Overall, 13/21 (62%) of verbal handoff data elements were more likely to be present following implementation whereas no data elements were less likely present. Implementation was associated with a decrease in interruption frequency pre versus post intervention (67% vs 40% of handoffs with interruptions, p=0.005) without a change in the median handoff duration (18.8 min vs 19.9 min, p=0.48) or changes in time spent in direct or indirect patient care activities. Implementation of the I-PASS Nursing Handoff Bundle was associated with widespread improvements in the verbal handoff process without a negative impact on nursing workflow. Implementation of I-PASS for nurses may therefore have the potential to significantly reduce medical errors and improve patient safety. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted

  4. Effect of Multiple Turbine Passage on Juvenile Snake River Salmonid Survival

    International Nuclear Information System (INIS)

    Ham, Kenneth D.; Anderson, James J.; Vucelick, Jessica A.

    2005-01-01

    This report describes a study conducted by Pacific Northwest National Laboratory to identify populations of migrating juvenile salmonids with a potential to be impacted by repeated exposure to turbine passage conditions. This study is part of a research program supported by the U.S. Department of Energy Wind/Hydropower Program. The program's goal is to increase hydropower generation and capacity while enhancing environmental performance. Our study objective is to determine whether the incremental effects of turbine passage during downstream migration impact populations of salmonids. When such a potential is found to exist, a secondary objective is to determine what level of effect of passing multiple turbines is required to decrease the number of successful migrants by 10%. This information will help identify whether future laboratory or field studies are feasible and design those studies to address conditions that present the greatest potential to improve dam survival and thus benefit fish and power generation

  5. Factors affecting route selection and survival of steelhead kelts at Snake River dams in 2012 and 2013

    Energy Technology Data Exchange (ETDEWEB)

    Harnish, Ryan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Colotelo, Alison H. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Xinya [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fu, Tao [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ham, Kenneth D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Zhiqun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Green, Ethan D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-03-31

    In 2012 and 2013, Pacific Northwest National Laboratory (PNNL) conducted a study that summarized the passage route proportions and route-specific survival rates of steelhead kelts that passed through Federal Columbia River Power System (FCRPS) dams. To accomplish this, a total of 811 steelhead kelts were tagged with Juvenile Salmon Acoustic Telemetry System (JSATS) transmitters. Acoustic receivers, both autonomous and cabled, were deployed throughout the FCRPS to monitor the downstream movements of tagged kelts. Kelts were also tagged with passive integrated transponder tags to monitor passage through juvenile bypass systems (JBS) and detect returning fish. The current study evaluated data collected in 2012 and 2013 to identify environmental, temporal, operational, individual, and behavioral variables that were related to forebay residence time, route of passage, and survival of steelhead kelts at FCRPS dams on the Snake River. Multiple approaches, including 3-D tracking, bivariate and multivariable regression modeling, and decision tree analyses were used to identify the environmental, temporal, operational, individual, and behavioral variables that had the greatest effect on forebay residence time, route of passage, and route-specific and overall dam passage survival probabilities for tagged kelts at Lower Granite (LGR), Little Goose (LGS), and Lower Monumental (LMN) dams. In general, kelt behavior and discharge appeared to work independently to affect forebay residence times. Kelt behavior, primarily approach location, migration depth, and “searching” activities in the forebay, was found to have the greatest influence on their route of passage. The condition of kelts was the single most important factor affecting their survival. The information gathered in this study may be used by dam operators and fisheries managers to identify potential management actions to improve in-river survival of kelts or collection methods for kelt reconditioning programs to aid

  6. Triplets pass their pressure test

    CERN Multimedia

    2007-01-01

    All the LHC inner triplets have now been repaired and are in position. The first ones have passed their pressure tests with flying colours. The repaired inner triplet at LHC Point 1, right side (1R). Ranko Ostojic (on the right), who headed the team responsible for repairing the triplets, shows the magnet to Robert Zimmer, President of the University of Chicago and of Fermi Research Alliance, who visited CERN on 20th August.Three cheers for the triplets! All the LHC inner triplets have now been repaired and are in position in the tunnel. Thanks to the mobilisation of a multidisciplinary team from CERN and Fermilab, assisted by the KEK Laboratory and the Lawrence Berkeley National Laboratory (LBNL), a solution has been found, tested, validated and applied. At the end of March this year, one of the inner triplets at Point 5 failed to withstand a pressure test. A fault was identified in the supports of two out of the three quadruple magne...

  7. Survival analysis models and applications

    CERN Document Server

    Liu, Xian

    2012-01-01

    Survival analysis concerns sequential occurrences of events governed by probabilistic laws.  Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis.Assumes only a minimal knowledge of SAS whilst enablin

  8. An analysis of the survivability of sensor darts in impacts with trees.

    Energy Technology Data Exchange (ETDEWEB)

    Prentice, John K. (Sci-Tac, Inc., Boulder, CO.); Gardner, David Randall

    2005-07-01

    A methodology was developed for computing the probability that the sensor dart for the 'Near Real-Time Site Characterization for Assured HDBT Defeat' Grand-Challenge LDRD project will survive deployment over a forested region. The probability can be decomposed into three approximately independent probabilities that account for forest coverage, branch density and the physics of an impact between the dart and a tree branch. The probability that a dart survives an impact with a tree branch was determined from the deflection induced by the impact. If a dart that was deflected so that it impacted the ground at an angle of attack exceeding a user-specified, threshold value, the dart was assumed to not survive the impact with the branch; otherwise it was assumed to have survived. A computer code was developed for calculating dart angle of attack at impact with the ground and a Monte Carlo scheme was used to calculate the probability distribution of a sensor dart surviving an impact with a branch as a function of branch radius, length, and height from the ground. Both an early prototype design and the current dart design were used in these studies. As a general rule of thumb, it we observed that for reasonably generic trees and for a threshold angle of attack of 5{sup o} (which is conservative for dart survival), the probability of reaching the ground with an angle of attack less than the threshold is on the order of 30% for the prototype dart design and 60% for the current dart design, though these numbers should be treated with some caution.

  9. Wavenumber–domain separation of rail contribution to pass-by noise

    NARCIS (Netherlands)

    Zea, Elias; Manzari, Luca; Squicciarini, Giacomo; Feng, Leping; Thompson, David; Arteaga, Ines Lopez

    2017-01-01

    In order to counteract the problem of railway noise and its environmental impact, passing trains in Europe must be tested in accordance to a noise legislation that demands the quantification of the noise generated by the vehicle alone. However, for frequencies between about 500 Hz and 1600 Hz, it

  10. Fledgling survival increases with development time and adult survival across north and south temperate zones

    Science.gov (United States)

    Lloyd, Penn; Martin, Thomas E.

    2016-01-01

    Slow life histories are characterized by high adult survival and few offspring, which are thought to allow increased investment per offspring to increase juvenile survival. Consistent with this pattern, south temperate zone birds are commonly longer-lived and have fewer young than north temperate zone species. However, comparative analyses of juvenile survival, including during the first few weeks of the post-fledging period when most juvenile mortality occurs, are largely lacking. We combined our measurements of fledgling survival for eight passerines in South Africa with estimates from published studies of 57 north and south temperate zone songbird species to test three predictions: (1) fledgling survival increases with length of development time in the nest; (2) fledgling survival increases with adult survival and reduced brood size controlled for development time; and (3) south temperate zone species, with their higher adult survival and smaller brood sizes, exhibit higher fledgling survival than north temperate zone species controlled for development time. We found that fledgling survival was higher among south temperate zone species and generally increased with development time and adult survival within and between latitudinal regions. Clutch size did not explain additional variation, but was confounded with adult survival. Given the importance of age-specific mortality to life history evolution, understanding the causes of these geographical patterns of mortality is important.

  11. High-resolution blood-pool-contrast-enhanced MR angiography in glioblastoma: tumor-associated neovascularization as a biomarker for patient survival. A preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Puig, Josep; Blasco, Gerard; Remollo, Sebastian; Hernandez, David; Pedraza, Salvador [Hospital Universitari Dr Josep Trueta, Research Unit of Diagnostic Imaging Institute (IDI), Department of Radiology [Girona Biomedical Research Institute] IDIBGI, Girona (Spain); Daunis-i-Estadella, Josep; Mateu, Gloria [University of Girona, Department of Computer Science, Applied Mathematics and Statistics, Girona (Spain); Alberich-Bayarri, Angel [La Fe Polytechnics and University Hospital, Biomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia (Spain); Essig, Marco [University of Manitoba, Department of Radiology, Winnipeg (Canada); Jain, Rajan [NYU School of Medicine, Division of Neuroradiology, Department of Radiology, New York, NY (United States); Puigdemont, Montserrat [Hospital Universitari Dr Josep Trueta, Catalan Institute of Oncology (ICO), Hospital Cancer Registry, Girona (Spain); Sanchez-Gonzalez, Javier [Philips Healthcare Iberica, Madrid (Spain); Wintermark, Max [Stanford University, Department of Radiology, Neuroradiology Division, Palo Alto, CA (United States)

    2016-01-15

    The objective of the study was to determine whether tumor-associated neovascularization on high-resolution gadofosveset-enhanced magnetic resonance angiography (MRA) is a useful biomarker for predicting survival in patients with newly diagnosed glioblastomas. Before treatment, 35 patients (25 men; mean age, 64 ± 14 years) with glioblastoma underwent MRI including first-pass dynamic susceptibility contrast (DSC) perfusion and post-contrast T1WI sequences with gadobutrol (0.1 mmol/kg) and, 48 h later, high-resolution MRA with gadofosveset (0.03 mmol/kg). Volumes of interest for contrast-enhancing lesion (CEL), non-CEL, and contralateral normal-appearing white matter were obtained, and DSC perfusion and DWI parameters were evaluated. Prognostic factors were assessed by Kaplan-Meier survival and Cox proportional hazards model. Eighteen (51.42 %) glioblastomas were hypervascular on high-resolution MRA. Hypervascular glioblastomas were associated with higher CEL volume and lower Karnofsky score. Median survival rates for patients with hypovascular and hypervascular glioblastomas treated with surgery, radiotherapy, and chemotherapy were 15 and 9.75 months, respectively (P < 0.001). Tumor-associated neovascularization was the best predictor of survival at 5.25 months (AUC = 0.794, 81.2 % sensitivity, 77.8 % specificity, 76.5 % positive predictive value, 82.4 % negative predictive value) and yielded the highest hazard ratio (P < 0.001). Tumor-associated neovascularization detected on high-resolution blood-pool-contrast-enhanced MRA of newly diagnosed glioblastoma seems to be a useful biomarker that correlates with worse survival. (orig.)

  12. Application of closed queueing network in the performance of a pick-and-pass order picking system

    NARCIS (Netherlands)

    Gaast, van der J.P.; Koster, de M.B.M.; Adan, I.J.B.F.; Resing, J.A.C.

    2011-01-01

    This paper presents a method for obtaining approximate solutions for pick-and-pass order picking systems with multiple classes of orders. The pick-and-pass system is decomposed into an entrance station, conveyor nodes and pick stations. A customer order needs to visit multiple pick stations, but the

  13. Performance of a novel clinical score, the Pediatric Asthma Severity Score (PASS), in the evaluation of acute asthma.

    Science.gov (United States)

    Gorelick, Marc H; Stevens, Molly W; Schultz, Theresa R; Scribano, Philip V

    2004-01-01

    To evaluate the reliability, validity, and responsiveness of a new clinical asthma score, the Pediatric Asthma Severity Score (PASS), in children aged 1 through 18 years in an acute clinical setting. This was a prospective cohort study of children treated for acute asthma at two urban pediatric emergency departments (EDs). A total of 852 patients were enrolled at one site and 369 at the second site. Clinical findings were assessed at the start of the ED visit, after one hour of treatment, and at the time of disposition. Peak expiratory flow rate (PEFR) (for patients aged 6 years and older) and pulse oximetry were also measured. Composite scores including three, four, or five clinical findings were evaluated, and the three-item score (wheezing, prolonged expiration, and work of breathing) was selected as the PASS. Interobserver reliability for the PASS was good to excellent (kappa = 0.72 to 0.83). There was a significant correlation between PASS and PEFR (r = 0.27 to 0.37) and pulse oximetry (r = 0.29 to 0.41) at various time points. The PASS was able to discriminate between those patients who did and did not require hospitalization, with area under the receiver operating characteristic curve of 0.82. Finally, the PASS was shown to be responsive, with a 48% relative increase in score from start to end of treatment and an overall effect size of 0.62, indicating a moderate to large effect. This clinical score, the PASS, based on three clinical findings, is a reliable and valid measure of asthma severity in children and shows both discriminative and responsive properties. The PASS may be a useful tool to assess acute asthma severity for clinical and research purposes.

  14. Integrative analysis of survival-associated gene sets in breast cancer.

    Science.gov (United States)

    Varn, Frederick S; Ung, Matthew H; Lou, Shao Ke; Cheng, Chao

    2015-03-12

    Patient gene expression information has recently become a clinical feature used to evaluate breast cancer prognosis. The emergence of prognostic gene sets that take advantage of these data has led to a rich library of information that can be used to characterize the molecular nature of a patient's cancer. Identifying robust gene sets that are consistently predictive of a patient's clinical outcome has become one of the main challenges in the field. We inputted our previously established BASE algorithm with patient gene expression data and gene sets from MSigDB to develop the gene set activity score (GSAS), a metric that quantitatively assesses a gene set's activity level in a given patient. We utilized this metric, along with patient time-to-event data, to perform survival analyses to identify the gene sets that were significantly correlated with patient survival. We then performed cross-dataset analyses to identify robust prognostic gene sets and to classify patients by metastasis status. Additionally, we created a gene set network based on component gene overlap to explore the relationship between gene sets derived from MSigDB. We developed a novel gene set based on this network's topology and applied the GSAS metric to characterize its role in patient survival. Using the GSAS metric, we identified 120 gene sets that were significantly associated with patient survival in all datasets tested. The gene overlap network analysis yielded a novel gene set enriched in genes shared by the robustly predictive gene sets. This gene set was highly correlated to patient survival when used alone. Most interestingly, removal of the genes in this gene set from the gene pool on MSigDB resulted in a large reduction in the number of predictive gene sets, suggesting a prominent role for these genes in breast cancer progression. The GSAS metric provided a useful medium by which we systematically investigated how gene sets from MSigDB relate to breast cancer patient survival. We used

  15. Biomechanical justification of the choice of optimum mode for passing the individual pursuit race

    Directory of Open Access Journals (Sweden)

    A.N. Kolumbet

    2018-04-01

    Full Text Available Purpose : biomechanical justification of the choice of optimum mode of passing competitive distance of 4 km individual pursuit on track. Material : The qualified cyclists (n=14 participated in researches. The modified stationary cycle Monark was used. Cyclists performed work in two modes - A and B. Results : The mode B is physiologically more favorable. The mode B should be considered as a model of passing a distance in preliminary races of individual pursuit. Work in the mode A demands terminal mobilization of organism functions. Work in the mode A is more effective in the achievement of sports result. It can be used only once in the final race of competitions. Conclusions : The received data should be considered as a demonstration of specific features of passing a distance in the competitive modes. The tactical variant of competitive program creation is defined by the individual functional state.

  16. Antioxidant defenses predict long-term survival in a passerine bird.

    Directory of Open Access Journals (Sweden)

    Nicola Saino

    2011-05-01

    Full Text Available Normal and pathological processes entail the production of oxidative substances that can damage biological molecules and harm physiological functions. Organisms have evolved complex mechanisms of antioxidant defense, and any imbalance between oxidative challenge and antioxidant protection can depress fitness components and accelerate senescence. While the role of oxidative stress in pathogenesis and aging has been studied intensively in humans and model animal species under laboratory conditions, there is a dearth of knowledge on its role in shaping life-histories of animals under natural selection regimes. Yet, given the pervasive nature and likely fitness consequences of oxidative damage, it can be expected that the need to secure efficient antioxidant protection is powerful in molding the evolutionary ecology of animals. Here, we test whether overall antioxidant defense varies with age and predicts long-term survival, using a wild population of a migratory passerine bird, the barn swallow (Hirundo rustica, as a model.Plasma antioxidant capacity (AOC of breeding individuals was measured using standard protocols and annual survival was monitored over five years (2006-2010 on a large sample of selection episodes. AOC did not covary with age in longitudinal analyses after discounting the effect of selection. AOC positively predicted annual survival independently of sex. Individuals were highly consistent in their relative levels of AOC, implying the existence of additive genetic variance and/or environmental (including early maternal components consistently acting through their lives.Using longitudinal data we showed that high levels of antioxidant protection positively predict long-term survival in a wild animal population. Present results are therefore novel in disclosing a role for antioxidant protection in determining survival under natural conditions, strongly demanding for more longitudinal eco-physiological studies of life-histories in

  17. Monitoring health spending increases: incremental budget analyses reveal challenging tradeoffs.

    Science.gov (United States)

    Hartman, Micah; Smith, Cynthia; Heffler, Stephen; Freeland, Mark

    2006-01-01

    With each passing decade, health care has consumed a larger share of gross domestic product (GDP) and Federal budgets. By the 2000-2004 period, society was willing to devote over 20 percent of the cumulative increase in GDP and the cumulative increase in Federal outlays towards health care. The financing challenges are expected to become more acute for private payers as well as Federal, State, and local budgets. With the implementation of Part D in 2006, the U.S. Office of Management and Budget projects that Federal budget pressures will heighten, bringing increased attention to Medicare's long-term fiscal outlook.

  18. A Compact Band-Pass Filter with High Selectivity and Second Harmonic Suppression.

    Science.gov (United States)

    Hadarig, Ramona Cosmina; de Cos Gomez, Maria Elena; Las-Heras, Fernando

    2013-12-03

    The design of a novel band-pass filter with narrow-band features based on an electromagnetic resonator at 6.4 GHz is presented. A prototype is manufactured and characterized in terms of transmission and reflection coefficient. The selective passband and suppression of the second harmonic make the filter suitable to be used in a C band frequency range for radar systems and satellite/terrestrial applications. To avoid substantial interference for this kind of applications, passive components with narrow band features and small dimensions are required. Between 3.6 GHz and 4.2 GHz the band-pass filter with harmonic suppression should have an attenuation of at least 35 dB, whereas for a passband, less than 10% is sufficient.

  19. First pass effect by infusing 99mTc-human serum albumin into the hepatic artery

    International Nuclear Information System (INIS)

    Ozawa, Takashi; Kimura, Kousaburou; Koyanagi, Yasuhisa

    1988-01-01

    The fundamental principles of intra-arterial infusion chemotherapy are thought to be increased local drug concentration and the ''first-pass'' effect. The concentration in the rest of the body can only be decreased if there is local elimination of the infused drug before reaching the systemic circulation. This is referred to as the ''first-pass'' effect. In the evaluation of ''first-pass'' effect, the uptake of liver after infusing 99m Tc-human serum albumin ( 99m Tc-HSA) in the hepatic artery by injecting the subcutaneously implanted silicon reservoir was compared with that obtained after intravenous administration of 99m Tc-HSA. In order to remove the factor of portal infusion, each count of liver up take had been continued for only 24 seconds after starting the liver uptake. The results are as follows : for 24 cases excepting 6 cases with catheter obstruction, the mean i.a./i.v. ratio was 7.92 ± 3.34 (range 3.25 to 17.25). Although the elimination rate of drugs in the liver varies with each drug, the infusion of intraarterial chemotherapy should be about 8 times more concentrative than intravenous administration on the ''first-pass'' effect. (author)

  20. Analysis of risk factors associated with unilateral hearing loss in children who initially passed newborn hearing screening.

    Science.gov (United States)

    Appelbaum, Eric N; Howell, Jessica B; Chapman, Derek; Pandya, Arti; Dodson, Kelley M

    2018-03-01

    To analyze 2007 Joint Committee on Infant Hearing (JCIH) risk factors in children with confirmed unilateral hearing loss (UHL) who initially passed newborn hearing screening. Retrospective record review of 16,108 infants who passed newborn hearing screening but had one or more JCIH risk factors prompting subsequent follow-up through the universal newborn hearing screening (UNHS) program in Virginia from 2010 to 2012. The study was reviewed and qualified as exempt by the Virginia Commonwealth University Institutional Review Board (IRB) and the Virginia Department of Health. Over the 2-year study period, 14896 (4.9% of total births) children passed UNHS but had the presence of one or more JCIH risk factor. Ultimately, we identified 121 babies from this group with confirmed hearing loss (0.7%), with 48 babies (0.2%) showing UHL. The most common risk factors associated with the development of confirmed UHL after passing the initial screen were neonatal indicators, craniofacial anomalies, family history, and stigmata of syndrome associated with hearing loss. Neonatal indicators and craniofacial anomalies were the categories most often found in children with confirmed unilateral hearing loss who initially passed their newborn hearing screen. While neonatal indicators were also the most common associated risk factor in all hearing loss, craniofacial abnormalities are relatively more common in children with UHL who initially passed newborn hearing screening. Further studies assessing the etiology underlying the hearing loss and risk factor associations are warranted. Copyright © 2018 Elsevier B.V. All rights reserved.