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Sample records for survival winnipeg manitoba

  1. 13th North American Caribou Workshop, 25-28 October 2010, Winnipeg, Manitoba, Canada.

    Directory of Open Access Journals (Sweden)

    Rolf Egil Haugerud (editor in chief

    2012-03-01

    Full Text Available The 13th North American Caribou Workshop which was held in Winnipeg, Manitoba, was a great success with more than 400 participants: people from Canada, the United States, Norway and Greenland, representatives from co-management and resource management boards across North America, First Nations, Inuit and Inuvialuit, governmental and non-governmental organisations, private companies, researchers, students and youth. The theme of the Workshop was Sustaining Caribou and their Landscapes – Knowledge to Action and the intent of the organizers was twofold: first, to provide participants with the opportunity to share scientific and traditional knowledge on different subspecies and ecotypes of Rangifer across the circumpolar North, the particularities of the different landscapes and land use management issues; second, to explore innovative ways to transfer knowledge to action, ensuring the long-term persistence of Rangifer throughout its range through the development of better governance structures, sound policies and effective communication.

  2. Prevalence and distribution of Baylisascaris procyonis in urban raccoons (Procyon lotor) in Winnipeg, Manitoba.

    Science.gov (United States)

    Sexsmith, Jennifer L; Whiting, Terry L; Green, Chris; Orvis, Sheldon; Berezanski, Dean J; Thompson, Amy B

    2009-08-01

    The prevalence of Baylisascaris procyonis was estimated in the urban raccoon population of Winnipeg through the fecal flotation of raccoon feces collected at active latrines and through gross postmortem and fecal flotation of samples collected from nuisance raccoons. Fecal flotation of latrine-collected feces was positive in 33 of 89 samples and, of 52 latrines identified, 26 were positive on 1 or more occasions. Trapped individual raccoons subjected to postmortem examination were positive in 57 of 114 animals captured. Comparing a single fecal flotation to the gold standard of finding adult worms in the small intestine had a sensitivity of 78.9% and specificity of 92.9%. This study suggests that carriage of Baylisascaris procyonis is widespread in raccoons in the Winnipeg urban ecosystem. Raccoon latrines in Winnipeg should be treated as infectious sites and efforts should be made to limit access of pets and people at risk to those sites.

  3. Patient and caregiver perspectives of health provision practices for First Nations and Métis women with gestational diabetes mellitus accessing care in Winnipeg, Manitoba.

    Science.gov (United States)

    Tait Neufeld, Hannah

    2014-09-26

    More North American Indigenous women are diagnosed with gestational diabetes mellitus (GDM) than the general population. Despite the number of health problems associated with GDM, few studies have been conducted that explore Indigenous women's understandings of GDM in an effort to develop appropriate and effective health strategies. A qualitative investigation was conducted to describe the experiences of First Nations and Métis women with GDM. Unstructured interviews and focus groups initially took place with 25 advisors such as maternal care providers and community representatives. Semi-structured explanatory model interviews were subsequently carried out with 29 First Nations and Métis women in Winnipeg, Manitoba, Canada. Divisions in health services, communication and cultural barriers exist, and limit prenatal care access as well as the consistent interpretation of diabetes education messages. Collectively the results suggest living with GDM can be overwhelming and underscore the need for health care providers to encourage self-efficacy towards effective management practices in the context of cultural safety.

  4. A social network-informed latent class analysis of patterns of substance use, sexual behavior, and mental health: Social Network Study III, Winnipeg, Manitoba, Canada.

    Science.gov (United States)

    Hopfer, Suellen; Tan, Xianming; Wylie, John L

    2014-05-01

    We assessed whether a meaningful set of latent risk profiles could be identified in an inner-city population through individual and network characteristics of substance use, sexual behaviors, and mental health status. Data came from 600 participants in Social Network Study III, conducted in 2009 in Winnipeg, Manitoba, Canada. We used latent class analysis (LCA) to identify risk profiles and, with covariates, to identify predictors of class. A 4-class model of risk profiles fit the data best: (1) solitary users reported polydrug use at the individual level, but low probabilities of substance use or concurrent sexual partners with network members; (2) social-all-substance users reported polydrug use at the individual and network levels; (3) social-noninjection drug users reported less likelihood of injection drug and solvent use; (4) low-risk users reported low probabilities across substances. Unstable housing, preadolescent substance use, age, and hepatitis C status predicted risk profiles. Incorporation of social network variables into LCA can distinguish important subgroups with varying patterns of risk behaviors that can lead to sexually transmitted and bloodborne infections.

  5. Libraries in Manitoba: MedlinePlus

    Science.gov (United States)

    ... this page: https://medlineplus.gov/libraries/manitoba.html Libraries in Manitoba To use the sharing features on this page, please enable JavaScript. Winnipeg Grace Hospital Library 300 Booth Drive Winnipeg, MB R3J 3M7 CANADA ...

  6. Arctic foxes, lemmings, and canada goose nest survival at cape Churchill, Manitoba

    Science.gov (United States)

    Reiter, M.E.; Andersen, D.E.

    2011-01-01

    We examined factors influencing Canada Goose (Branta canadensis interior) annual nest success, including the relative abundance of collared lemmings (Dicrostonyx richardsoni), arctic fox (Alopex lagopus) den occupancy, nest density, and spring phenology using data collected during annual Canada Goose breeding area surveys at Cape Churchill, Manitoba. Nest density and arctic fox den occupancy strongly influenced Canada Goose nest success. High nest density resulted in higher nest success and high den occupancy reduced nest success. Nest success was not influenced by lemming abundance in the current or previous year as predicted by the "bird-lemming" hypothesis. Reducing arctic fox abundance through targeted management increased nest survival of Canada Geese; a result that further emphasizes the importance of arctic fox as nest predators in this system. The spatial distribution of nest predators, at least for dispersed-nesting geese, may be most important for nest survival, regardless of the abundance of small mammals in the local ecosystem. Further understanding of the factors influencing the magnitude and variance in arctic fox abundance in this region, and the spatial scale at which these factors are realized, is necessary to fully explain predator-prey-alternative prey dynamics in this system. ?? 2011 by the Wilson Ornithological Society.

  7. Cancer incidence, morbidity, and survival in Canadian first nation children: a Manitoba population-based study from the cancer in young people in Canada (CYP-C) registry.

    Science.gov (United States)

    Stammers, David M; Israels, Sara J; Lambert, Pascal J; Cuvelier, Geoff D E

    2014-12-01

    Health disparities between Canadian First Nation (FN) people and the rest of the national population exist. No studies have specifically documented cancer-related health outcomes in Canadian FN children. The purpose of this study was to describe the incidence of pediatric malignancies in Manitoba FN children, and to compare morbidity patterns and survival between FN and non-FN children with cancer in the Canadian province of Manitoba. A retrospective, population-based review of all children (0-14.99 years) diagnosed with malignancy (2001-2008) in Manitoba, Canada was undertaken using the Cancer in Young People in Canada registry. FN children were compared to the non-FN population for markers of morbidity and survival. The average annual age-standardized incidence rate for all childhood cancers in FN children was 132 per 1,000,000 per year. 240 children were included in the morbidity and survival analyses (38 FN; 202 non-FN). No differences were found between FN and non-FN children in time from first presentation of symptoms to consultation with an oncology specialist or diagnosis, or number of hospital admissions / total days of admission for treatment complications. Overall survival was inferior for FN children in univariable analysis (P = 0.048) but not when risk group was included in a multivariable analysis (P = 0.15). No difference in event free survival or cumulative incidence of relapse was identified. The estimated incidence of childhood cancers in the Manitoba FN population is similar to provincial incidence rates. No differences in morbidity patterns or survival were found between Manitoba FN and non-FN children with cancer. © 2014 Wiley Periodicals, Inc.

  8. Field studies on the transmission and survival of Cyclocoelum mutabile (Digenea) infections in natural snail populations in southern Manitoba, Canada.

    Science.gov (United States)

    McKindsey, C W; McLaughlin, J D

    1995-08-01

    The transmission of Cyclocoelum mutabile to snails was examined under natural conditions by sampling the snail communities of 4 natural ponds that had been exposed experimentally to infection by laboratory-infected coots (Fulica americana). Five of 6 snail species in the ponds, Physa jennessi, Promenetus exacuous, Armiger crista, Gyraulus parvus, and Stagnicola elodes, became infected. No natural infections were found in the few Helisoma trivolvis examined. The second most abundant species Promenetus exacuous was infected most often, whereas Physa jennessi, the most abundant species present, was rarely infected. The temporal pattern of infections in the snail community suggests the transmission window of this parasite in southern Manitoba is limited by both the 14 C hatching threshold of the fluke eggs and the seasonality of ovigerous infections in the coot host. No naturally overwintering infections were found in snails from these ponds, which were examined the following spring. None of the 1,120 laboratory-infected snails placed in cages and held overwinter in the ponds survived, whereas 14 of the 1,120 uninfected control snails kept in the same cages survived. These results are consistent with the hypothesis that C. mutabile must be reestablished in northern waterfowl breeding areas each spring.

  9. Understanding drought in the Winnipeg River basin, Manitoba

    National Research Council Canada - National Science Library

    St. George, S

    2003-01-01

    .... This project will analyze streamflow records to determine if low flows occur in a predictable, periodic manner and establish if extreme low flows in the WRB are associated with specific atmospheric circulation patterns...

  10. Effectiveness of breed-specific legislation in decreasing the incidence of dog-bite injury hospitalisations in people in the Canadian province of Manitoba

    OpenAIRE

    Raghavan, Malathi; Martens, Patricia J.; Chateau, Dan; Burchill, Charles

    2012-01-01

    Background The city of Winnipeg was the first among several jurisdictions in Manitoba, Canada, to introduce breed specific legislation (BSL) by banning pit-bull type dogs in 1990. The objective of the present work was to study the effectiveness of BSL in Manitoba. Methods Temporal differences in incidence of dog-bite injury hospitalisations (DBIH) within and across Manitoba jurisdictions with and without BSL were compared. Incidence was calculated as the number of unique cases of DBIH divided...

  11. Long-term time trends in incidence, survival and mortality of lymphomas by subtype among adults in Manitoba, Canada: a population-based study using cancer registry data.

    Science.gov (United States)

    Ye, Xibiao; Mahmud, Salaheddin; Skrabek, Pamela; Lix, Lisa; Johnston, James B

    2017-07-17

    To examine 30-year time trends in incidence, survival and mortality of lymphomas by subtype in Manitoba, Canada. Lymphoma cases diagnosed between 1984 and 2013 were classified according to the 2008 WHO classification system for lymphoid neoplasms. Death data (1984-2014) were obtained from the Manitoba Vital Statistics Agency. To examine time trends in incidence and mortality, we used joinpoint regression to estimate annual percentage change and average annual percentage change. Age-period-cohort modelling was conducted to measure the effects of age, period and cohort on incidence and mortality time trends. We estimated age-specific and standardised 5-year relative survival and used Poisson regression model to test time trends in relative survival. Total Hodgkin lymphoma (HL) incidence in men and women was stable during the study period. Age-standardised total non-Hodgkin lymphoma (NHL) incidence increased by 4% annually until around 2000, and the trend varied by sex and NHL subtype. Total HL mortality continuously declined (by 2.5% annually in men and by 2.7% annually in women), while total NHL mortality increased (by 4.4% annually in men until 1998 and by 3.2% annually in women until 2001) and then declined (by 3.6% annually in men and by 2.5% annually in women). Age-standardised 5-year relative survival for HL improved from 72.6% in 1984-1993 to 85.8% in 2004-2013, and for NHL from 57.0% in 1984-1993 to 67.5% in 2004-2013. Survival improvement was also noted for NHL subtypes, although the extent varied, with the greatest improvement for follicular lymphoma (from 65.3% in 1984-1993 to 87.6% in 2004-2013). Time trends were generally consistent with those reported in other jurisdictions in total HL and NHL incidence, but were unique in incidence for HL and for NHL subtypes chronic/small lymphocytic leukaemia/lymphoma, diffuse large B cell lymphoma and follicular lymphoma. Survival improvements and mortality reductions were seen for HL and NHL in both sexes.

  12. Petroluem in Manitoba. Le petrole au Manitoba

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    This document presents an overview of the Manitoba petroleum industry, with a historical outline of the industry from the first exploration efforts, through the petroleum boom of the eighties, and the evolution of refining in Manitoba. The origins of petroleum are briefly examined. In addition, the techniques of petroleum exploration, drilling, production, transport and storage are reviewed. The present situation of the Manitoba petroleum industry, the level of oil and gas reserves, future prospects, and the role of the Petroleum Division of Manitoba Energy and Mines are also described. Includes glossary.

  13. Ethnicity and geographic distribution of pediatric chronic ataxia in Manitoba.

    Science.gov (United States)

    Salman, Michael S; Masood, Shaheen; Azad, Meghan; Chodirker, Bernard N

    2014-01-01

    Genetic and environmental factors are important determinants of disease distribution. Several disorders associated with ataxia are known to occur more commonly in certain ethnic groups; for example, the disequilibrium syndrome in the Hutterites. The aim of this study was to determine the ethnic and geographic distribution of pediatric patients with chronic ataxia in Manitoba, Canada. We identified 184 patients less than 17 years-of-age with chronic ataxia during 1991-2008 from multiple sources. Their diagnosis, ethnicity and place of residence were determined following a chart review. Most patients resided in Manitoba (N=177) and the majority in Winnipeg, the provincial capital. Thirty five Aboriginal, 29 Mennonite and 11 Hutterite patients resided in Manitoba. The latter two groups were significantly overrepresented in our cohort. Ataxia telangiectasia, mitochondrial disorders, and non-progressive ataxia of unknown etiology associated with pyramidal tracts signs and developmental delay were significantly more common in Mennonite patients. Four of five patients with neuronal migration disorders associated with chronic ataxia were Aboriginal. Few isolated disorders with chronic ataxia occurred in the 11 Hutterite patients including a Joubert syndrome related disorder. Three disorders associated with chronic ataxia were more prevalent than expected in Mennonites in Manitoba. Few rare disorders were more prevalent in the Hutterite and Aboriginal population. Further research is needed to determine the risk factors underlying these variations in prevalence within different ethnic groups. The unique risk factor profiles of each ethnic group need to be considered in health promotion endeavors. Ethnie et distribution géographique de l'ataxie chronique chez des patients d'âge pédiatrique au Manitoba.

  14. Microplastic contamination in Lake Winnipeg, Canada.

    Science.gov (United States)

    Anderson, Philip J; Warrack, Sarah; Langen, Victoria; Challis, Jonathan K; Hanson, Mark L; Rennie, Michael D

    2017-06-01

    Microplastics are an emerging contaminant of concern in aquatic ecosystems. To better understand microplastic contamination in North American surface waters, we report for the first time densities of microplastics in Lake Winnipeg, the 11th largest freshwater body in the world. Samples taken 2014 to 2016 revealed similar or significantly greater microplastic densities in Lake Winnipeg compared with those reported in the Laurentian Great Lakes. Plastics in the lake were largely of secondary origin, overwhelmingly identified as fibres. We detected significantly greater densities of microplastics in the north basin compared to the south basin of the lake in 2014, but not in 2015 or 2016. Mean lake-wide densities across all years were comparable and not statistically different. Scanning electron microscopy with energy dispersive X-ray spectroscopy indicated that 23% of isolated particles on average were not plastic. While the ecological impact of microplastics on aquatic ecosystems is still largely unknown, our study contributes to the growing evidence that microplastic contamination is widespread even around sparsely-populated freshwater ecosystems, and provides a baseline for future study and risk assessments. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Report on acoustic and vibration measurements on 250 MVA transformer at St. Vital Station, Winnipeg, Manitoba

    Energy Technology Data Exchange (ETDEWEB)

    Weissman, K. [QuietPower Systems, Inc., New York, NE (United States); McLoughlin, M. [Noise Cancellation Technologies, Inc., Linthicum, MD (United States); Schott, R. [Western Canada Testing, Inc., Portage Laprairie, MB (Canada); Tennese, G. [Manitoba Hydro, Winnipeg, MB (Canada); Daneryd, A. [SECRC ABB Corporate Research, Vasteras (Sweden)

    1998-09-01

    Vibroacoustic behaviour of a power transformer was characterized prior to employing active noise control (ANC) to control transformer noise. The effect of changes in temperature and loading conditions on the vibration pattern of the transformer tank received particular attention. The transformer quieting technology has been developed and implemented by QuietPower Systems of New York and Noise Cancellation Technologies Inc., of Maryland. Results of the study will be used to ensure that actuator placement is appropriate for each of the seasons experienced throughout the year, as well as to build boundary element and finite element models of the tank vibration and the associated radiated noise. Boundary element results show that the first four harmonics are the primary contributors to radiated noise. The finite element model used to examine the modal response of the tank structure showed high modal densities, even around the lower order harmonics (120 Hz). This can be interpreted to mean that statistical techniques normally associated with high frequency noise problems may be applicable here because of the high modal density. Results of the completed summer and winter measurements permit an evaluation of the effects of loading conditions, temperature and other environmental factors on transformer noise. Appendix B contains the results of numerical simulations on a 250 MVA transformer. 3 refs., 72 figs., 2 appendices.

  16. Angel's Trumpet (Datura stramonium) poisoning and delirium in adolescents in Winnipeg, Manitoba: Summer 2006.

    Science.gov (United States)

    Wiebe, Tannis H; Sigurdson, Eric S; Katz, Laurence Y

    2008-03-01

    Over the course of the summer of 2006, four adolescent patients were hospitalized because of intentional Datura stramonium (Angel's Trumpet) ingestion. Their records were reviewed for the presence of signs and symptoms of toxicity, clinical course, treatment and outcome. All four patients had a decreased level of consciousness measured by the Glasgow Coma Scale, visual hallucinations, dilated pupils and agitation. The changes in mental status are characteristic of delirium. All four patients were known to abuse substances. The average length of hospitalization was two days. No serious complications were encountered during hospitalization and a full recovery was noted in all patients. The use of sedation and restraints were sufficient treatment modalities. Health care workers should consider anticholinergic plant ingestion as a cause for abrupt onset of delirium.

  17. Angel’s Trumpet (Datura stramonium) poisoning and delirium in adolescents in Winnipeg, Manitoba: Summer 2006

    Science.gov (United States)

    Wiebe, Tannis H; Sigurdson, Eric S; Katz, Laurence Y

    2008-01-01

    Over the course of the summer of 2006, four adolescent patients were hospitalized because of intentional Datura stramonium (Angel’s Trumpet) ingestion. Their records were reviewed for the presence of signs and symptoms of toxicity, clinical course, treatment and outcome. All four patients had a decreased level of consciousness measured by the Glasgow Coma Scale, visual hallucinations, dilated pupils and agitation. The changes in mental status are characteristic of delirium. All four patients were known to abuse substances. The average length of hospitalization was two days. No serious complications were encountered during hospitalization and a full recovery was noted in all patients. The use of sedation and restraints were sufficient treatment modalities. Health care workers should consider anticholinergic plant ingestion as a cause for abrupt onset of delirium. PMID:19252697

  18. Food Perceptions and Concerns of Aboriginal Women Coping with Gestational Diabetes in Winnipeg, Manitoba

    Science.gov (United States)

    Neufeld, Hannah Tait

    2011-01-01

    Objective: To describe how Aboriginal women in an urban setting perceive dietary treatment recommendations associated with gestational diabetes mellitus (GDM). Design: Semi-structured explanatory model interviews explored Aboriginal women's illness experiences with GDM. Setting and Participants: Twenty-nine self-declared Aboriginal women who had…

  19. The Association Between Community Stressors and Asthma Prevalence of School Children in Winnipeg, Canada

    Directory of Open Access Journals (Sweden)

    Anita L. Kozyrskyj

    2012-02-01

    Full Text Available It is generally surmised that community stressors have an incubating effect for a variety of diagnoses on maternal and child health. This is of public health significance, as children of mothers facing long-term distress were found to have a 60% higher risk for asthma diagnosis at age 7 in Manitoba, Canada. Our objective was to determine the association of community stressors with childhood asthma prevalence in Winnipeg, Canada from participants who completed the Study of Asthma, Genes and the Environment (SAGE survey administered in 2002–2003 to a birth cohort from 1995. Measures of community socioeconomic makeup and community disorder with rank ordinalized by quintile at the census tract level were obtained from the 1996 Canada Census. Crime data (annual incidence per 10,000 persons by neighbourhood profile for 2001 was provided by the Winnipeg Police Service. Dichotomous caregiver report of child asthma along with other indicators from the geocoded SAGE survey allowed linkage to 23 neighbourhood profiles. Multilevel logistic regression analyses were performed to estimate the effect of community stressors on childhood asthma prevalence for birth and non-birth home children (N = 1472 and children resident of birth homes at age 7 or 8 (N = 698. After adjusting for individual risk factors, children resident of birth homes in a high thefts over $5,000 neighbourhood profile were twice as likely (Adjusted OR, 2.05; 95% CI, 1.11–3.81 to have report of asthma compared to children in a lower thefts over $5,000 profile, with community thefts over $5,000 explaining over half of the observed neighbourhood variation in asthma.

  20. Land use change impacts on water quality in three lake winnipeg watersheds.

    Science.gov (United States)

    Yang, Qi; Leon, Luis F; Booty, William G; Wong, Isaac W; McCrimmon, Craig; Fong, Phil; Michiels, Patsy; Vanrobaeys, Jason; Benoy, Glenn

    2014-09-01

    Lake Winnipeg eutrophication results from excess nutrient loading due to agricultural activities across the watershed. Estimating nonpoint-source pollution and the mitigation effects of beneficial management practices (BMPs) is an important step in protecting the water quality of streams and receiving waters. The use of computer models to systematically compare different landscapes and agricultural systems across the Red-Assiniboine basin has not been attempted at watersheds of this size in Manitoba. In this study, the Soil and Water Assessment Tool was applied and calibrated for three pilot watersheds of the Lake Winnipeg basin. Monthly flow calibration yielded overall satisfactory Nash-Sutcliffe efficiency (NSE), with values above 0.7 for all simulations. Total phosphorus (TP) calibration NSE ranged from 0.64 to 0.76, total N (TN) ranged from 0.22 to 0.75, and total suspended solids (TSS) ranged from 0.29 to 0.68. Based on the assessment of the TP exceedance levels from 1993 to 2007, annual loads were above proposed objectives for the three watersheds more than half of the time. Four BMP scenarios based on land use changes were studied in the watersheds: annual cropland to hay land (ACHL), wetland restoration (WR), marginal annual cropland conversion to hay land (MACHL), and wetland restoration on marginal cropland (WRMAC). Of these land use change scenarios, ACHL had the greatest impact: TSS loads were reduced by 33 to 65%, TN by 58 to 82%, and TP by 38 to 72% over the simulation period. By analyzing unit area and percentage of load reduction, the results indicate that the WR and WRMAC scenarios had a significant impact on water quality in high loading zones in the three watersheds. Such reductions of sediment, N, and P are possible through land use change scenarios, suggesting that land conservation should be a key component of any Lake Winnipeg restoration strategy. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil

  1. Manitoba's School Psychology, Circa 2016

    Science.gov (United States)

    Mallin, Barry; Bednarczyk, George; Hanson, Dawn

    2016-01-01

    While the geographic landscape of Manitoba has changed very little since the last review of school psychology in Manitoba was published 15 years ago, the school psychology landscape here has changed considerably, and we continue to be alive, well, and flourishing. Two previous articles in the "Canadian Journal of School Psychology"…

  2. Nutrient delivery to Lake Winnipeg from the Red-Assiniboine River Basin – A binational application of the SPARROW model

    Science.gov (United States)

    Benoy, Glenn A; Jenkinson, R. Wayne; Robertson, Dale; Saad, David A.

    2016-01-01

    Excessive phosphorus (TP) and nitrogen (TN) inputs from the Red–Assiniboine River Basin (RARB) have been linked to eutrophication of Lake Winnipeg; therefore, it is important for the management of water resources to understand where and from what sources these nutrients originate. The RARB straddles the Canada–United States border and includes portions of two provinces and three states. This study represents the first binationally focused application of SPAtially Referenced Regressions on Watershed attributes (SPARROW) models to estimate loads and sources of TP and TN by jurisdiction and basin at multiple spatial scales. Major hurdles overcome to develop these models included: (1) harmonization of geospatial data sets, particularly construction of a contiguous stream network; and (2) use of novel calibration steps to accommodate limitations in spatial variability across the model extent and in the number of calibration sites. Using nutrient inputs for a 2002 base year, a RARB TP SPARROW model was calibrated that included inputs from agriculture, forests and wetlands, wastewater treatment plants (WWTPs) and stream channels, and a TN model was calibrated that included inputs from agriculture, WWTPs and atmospheric deposition. At the RARB outlet, downstream from Winnipeg, Manitoba, the majority of the delivered TP and TN came from the Red River Basin (90%), followed by the Upper Assiniboine River and Souris River basins. Agriculture was the single most important TP and TN source for each major basin, province and state. In general, stream channels (historically deposited nutrients and from bank erosion) were the second most important source of TP. Performance metrics for the RARB SPARROW model are similarly robust compared to other, larger US SPARROW models making it a potentially useful tool to address questions of where nutrients originate and their relative contributions to loads delivered to Lake Winnipeg.

  3. Manitoba Williston Basin activity update

    Energy Technology Data Exchange (ETDEWEB)

    Fox, J. [Manitoba Industry, Trade and Mines, Winnipeg, MB (Canada)

    2003-07-01

    This presentation described the drilling activity in Manitoba from 1998 to 2002 with particular emphasis on horizontal well drilling and production by geologic formation, including the Bakken, Lodgepole and the Lower Amaranth Formations. A total of 97 wells were drilled in Manitoba in 2002. The most active drillers were EOG Resources Canada with a total of 34 wells. Tundra Oil and Gas was close behind with 28 wells, followed by Chevron Canada Resources with 21 wells. Horizontal drilling had a major impact in Manitoba between 1998-2002, representing 30 per cent of drilling activity focused on the Waskada, Virden and Daly fields. Expansion activity throughout the province contributed to the overall increase in oil production for four consecutive years. Annual production reached 650.7 10{sup 3}m{sup 3} in 2001. Manitoba's top 5 producers are Chevron Canada Resources, Tundra Oil and Gas, EOG Resources Canada, Canadian Natural Resources and NCE Petrofund. Together, they account for 89 per cent of Manitoba's production. This paper also described some of the initiatives that Manitoba's Department of Industry, Trade and Mines has taken to improve oil and gas regulations through proposed amendments to the Oil and Gas Act, a review of the Manitoba Drilling Incentive Program, battery re-permitting, and a strategy for managing orphaned wells. 3 figs.

  4. Horizontal drilling activity in Manitoba

    Energy Technology Data Exchange (ETDEWEB)

    Fox, J.

    1997-04-01

    An update of horizontal well drilling in Manitoba was provided. Manitoba`s productive formations are: (1) the Bakken Formation, (2) the Lodgepole Formation, (3) the Mission Canyon Formation, (4) the Amaranth Formation, and (5) the Melita Formation. A total of 28 exploratory wells and 29 development wells, including 11 horizontal wells were drilled in 1996. The 11 horizontal wells accounted for 30 per cent of the drilling meterage. The leading drillers for horizontal wells in Manitoba are Tundra Oil and Gas, Chevron, Anderson and HCO. Production from horizontal wells in 1996 totaled 310 cubic meter per day. To date, no horizontal wells have been drilled in the Bakken Formation. The least successful horizontal well application has been in the Lodgepole Formation. A summary of horizontal well production was provided for each Formation. 4 tabs., 10 figs.

  5. Influenza 1918: disease, death and struggle in Winnipeg

    National Research Council Canada - National Science Library

    Jones, Esyllt Wynne

    2007-01-01

    ... communities within the city, including its role in the eruption of the largest labour confrontation in Canadian history, the Winnipeg General Strike of 1919. Arguing that labour historians have largely ignored the impact of infectious disease upon the working class, Jones draws on a wide range of primary sources including mothers' allowance and orphanage case fi...

  6. Trends in pediatric dental surgery for severe early childhood caries in Manitoba, Canada.

    Science.gov (United States)

    Schroth, Robert J; Pang, Jordan L; Levi, Jeremy A; Martens, Patricia J; Brownell, Marni D

    2014-01-01

    Caries is the most common chronic disease of childhood, and severe forms may necessitate rehabilitative dental surgery. In this study, administrative data related to pediatric dental surgery performed under general anesthesia to treat severe early childhood caries in Manitoba, Canada, were reviewed to determine trends in pediatric dental surgery, as well as geographic, regional and socio-economic variations in surgical rates. The total number of dental surgery cases performed under general anesthesia was obtained from provincial administrative databases for fiscal years from 1997-98 to 2006-07. Codes from the International Classification of Diseases and Related Health Problems (9th or 10th revision, as appropriate) were used to identify children who underwent extractions under general anesthesia for a slightly earlier fiscal year period (1996-97 to 2005-06). Each 10-year period was divided into two 5-year periods for comparisons over time. Analyses included descriptive and bivariate statistics, with the data being disaggregated by regional health authority (RHA) or by community area (for Winnipeg). Comparisons for which p ≤ 0.05 were defined as statistically significant. A total of 18,544 children had dental surgery under general anesthesia between 1997-98 and 2006-07 (mean age ± standard deviation 3.28 ± 1.02 years). Many of the children requiring surgery resided in one northern RHA (26.8%) or the Winnipeg RHA (23.8%). More than half of the RHAs (7/11) displayed significant increases in the rate of surgery, with northern RHAs having the highest rates. Within Winnipeg, 3 of the 12 community areas had significant increases in the rate of surgery. Two inner-city neighborhoods accounted for nearly 50% of surgical cases. The rate of extractions under general anesthesia increased significantly in 6 of the 11 RHAs, with northern RHAs having the highest rates. Four Winnipeg communities experienced significant increases in the extraction rate over time. Pediatric

  7. Project Ida: Manitoba's Telecommunications Experiment.

    Science.gov (United States)

    Hlynka, Denis; Hurly, Paul

    1981-01-01

    The Manitoba Telephone System has established an experimental integrated home information system called Project Ida in a trial group of 100 homes. Discussed here are the origin, current operation, and future prospects of this system, which includes videotex, fire monitoring, telemetering, and educational television. (Author/JJD)

  8. Manitoba 2004 oil activity review

    Energy Technology Data Exchange (ETDEWEB)

    Fox, J.N. [Manitoba Industry, Economic Development and Mines, Winnipeg, MB (Canada)

    2005-07-01

    This paper presented data on oil and gas activities in Manitoba during 2004, the busiest year in Manitoba's oil patch since the mid 1980s. Increases in the leasing of Crown and freehold acreage were also noted, with accompanying increases in drilling activity for the latter part of 2004. Details of Crown land sales were presented, with a total of 43,725 hectares of crown oil and gas rights under lease. During 2004, over 15,000 hectares of Crown oil and gas leases were sold, the highest figures since 1997. More wells were licensed and drilled in 2004 than in any year since 1986. Overall drilling success rate was 96.7 per cent. Details of top drillers in Manitoba were presented, with drilling activity focused in Waskada and Daly fields and the Sinclair area. Oil production increased by 0.7 per cent, with 1474 wells in production. Daily oil production statistics were presented, with the total value of Manitoba's oil production being $196 million. Details of the top 5 producers were provided, in addition to details of horizontal well production. Recent developments in Sinclair Field, Pierson L. Amaranth MC 3b A Pool, Waskada L. Amaranth I Pool and Virden Lodgepole D Pool were reviewed. The Manitoba Drilling Incentive Program was discussed with reference to the following enhancements: new well incentives, horizontal well incentives; holiday oil volume accounts; and marginal well major workover programs. Various Oil and Gas Act amendments were reviewed. In addition, the Williston Basin Architecture and Hydrocarbon Potential Project was discussed. 3 figs.

  9. Canada's National Building Stone: Tyndall Stone from Manitoba

    Science.gov (United States)

    Pratt, Brian R.; Young, Graham A.; Dobrzanski, Edward P.

    2016-04-01

    Tyndall Stone is a distinctively mottled and highly fossiliferous dolomitic limestone that belongs to the Selkirk Member of the Red River Formation, of Late Ordovician (Katian) age. It has been quarried at Garson, Manitoba, 37 km northeast of Winnipeg, since 1895, although other quarries in the area go back to 1832. Tyndall Stone, so named because it was shipped by rail from nearby Tyndall, is currently produced by Gillis Quarries Limited. It has various uses as a dimension stone. Large slabs, most often cut parallel to bedding, face the exterior or interior of many important buildings such as the Parliament Buildings and the Canadian Museum of Civilization in the Ottawa area, the Empress Hotel in Victoria, and the provincial legislatures in Winnipeg and Regina, as well as many commercial buildings especially in the Canadian prairies. At the quarries, the stone is cut vertically, using eight foot (2.44 m) diameter saws mounted on one hundred foot (30.5 m) tracks, then split into 6-8 tonne blocks that are moved using front-end loaders. Gillis Quarries operates a large finishing plant with an area of about 4000 m2. Stone is processed along advanced cutting lines that feature eight primary saws and six gantry saw stations, allowing it to be made into a variety of sizes, shapes, and finishes. The Selkirk Member is 43 m thick and the stone is extracted from a 6-8 m thick interval within the lower part. The upper beds tend to be more buff-coloured than the grey lower beds due to weathering by groundwater. The stone is massive, but extracted blocks are less than ~1m thick due to splitting along stylolites. Consisting of bioturbated wackestone to packstone, the Tyndall Stone was deposited in a shallow-marine environment within the photic zone, in the central part of the vast equatorial epicontinental sea that covered much of Laurentia. Scattered thin, bioclastic grainstone lenses record brief, low-energy storm events. The distinctive mottles are formed by dolomitized

  10. Advancing Interprofessional Collaborative Teams in the Winnipeg Health Region.

    Science.gov (United States)

    Klaasen, Kathleen; Bowman, Susan; Komenda, Paul

    2016-01-01

    This project developed an evaluation platform aimed at diagnosing team functioning using evidence-informed, measurable indicators to provide an actionable roadmap to guide teams in improving their interprofessional collaborative team performance. A scoping literature review, stakeholder consultation, survey and focus groups were conducted to inform both the final selection of eight indicators of effective, high-performing teams and the process to assess and evaluate teams against these indicators. The program was piloted with two interprofessional teams in the Winnipeg Health Region. Focus groups and questionnaires were used to evaluate the program.

  11. Take a Walk! Innovative Programming from Winnipeg Public Library

    Directory of Open Access Journals (Sweden)

    Kirsten Wurmann

    2016-07-01

    Full Text Available Historical walks, literary walks, and walking book clubs – learn how Winnipeg Public Library is taking it outside. Rebecca Solnit in her book Wanderlust: A History of Walking writes: “Walking shares with making and working that crucial element of engagement of the body and the mind with the world, of knowing the world through the body and the body through the world.” As libraries work hard to share knowledge with their communities and to engage patrons in new ways, this presentation addresses the practicalities of creating a program that speaks uniquely to your own neighbourhood and patrons: Learn about the walking programs offered by various Winnipeg Public Library branches; recognize the benefits of these programs and how they can relate to library programming goals and strategic plans; and identify resources that can help you develop your own walking programs. This summary is based on a poster presentation given at the annual OLA Super Conference held in Toronto, Ontario on January 27-30, 2016. Les promenades historiques, les promenades littéraires et les clubs de marche littéraires - apprenez comment la bibliothèque publique de Winnipeg profite de l’extérieur. Dans son livre Wanderlust: A History of Walking Rebecca Solnit écrit: “Se promener partage avec faire et travailler cet élément crucial d’engagement du corps et de l’esprit avec le monde, de connaître le monde à travers le corps et le corps à travers le monde.” Comme des bibliothèques travaillent fort pour partager des informations avec leurs communautés et pour engager des clients de nouvelles façons, cette présentation porte sur l’applicabilité de créer un programme adapté aux particularités de votre propre quartier et de vos clients : renseignez-vous sur les programmes de marche offerts par des filiales différentes de la bibliothèque publique de Winnipeg; Reconnaissez des avantages de ces programmes et comment ils peuvent se rapporter aux

  12. Characteristics of hospital admissions for pneumonia in HIV-positive individuals in Winnipeg, Manitoba: a cross-sectional retrospective analysis.

    Science.gov (United States)

    van Gaalen, S; Duff, Michael; Arroyave, Luisa F; Rueda, Zulma Vanessa; Kasper, Ken; Keynan, Y

    2018-02-01

    Lung infection in human immunodeficiency virus (HIV)-positive individuals remains an important cause of morbidity and mortality, even in the current antiretroviral therapy era. Pneumonia is the most common cause of admission in HIV-positive individuals in our centre as reported in a previously published study. The objective of this retrospective observational study was to further characterize these admissions, with respect to index of disease severity at presentation, organisms identified, and investigations pursued including bronchoalveolar lavage (BAL). There were 123 unique patients accounting for a total of 209 admissions from 2005 to 2015. An organism was isolated in only 33% of all admissions (68/209). The most common organism was Pneumocystis jirovecii with a frequency of 29% of all admissions. Eighty-seven percent of presentations were mild, and 13% were moderate by CURB-65 criteria. A total of 39 BALs were performed, of which 27 yielded an organism (69%). Considering the burden of disease, low diagnostic yield of the current diagnostic strategy and increased morbidity and mortality caused by pneumonia in HIV-positive individuals, further methods are needed to more accurately target therapy. The preponderance of mild disease in this study suggests that better diagnostic tests may identify individuals that can be candidates for outpatient therapy.

  13. Space Radar Image of Altona, Manitoba, Canada

    Science.gov (United States)

    1994-01-01

    This is an X-band seasonal image of the Altona test site in Manitoba, Canada, about 80 kilometers (50 miles) south of Winnipeg. The image is centered at approximately 49 degrees north latitude and 97.5 degrees west longitude. This image was acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the space shuttle Endeavour on April 11, 1994, during the first flight of the radar system, and on October 2, 1994, during the second flight of SIR-C/X-SAR. The image channels have the following color assignments: red represents data acquired on April 11, 1994; green represents data acquired on October 2, 1994; blue represents the ratio of the two data sets. The test site is located in the Red River Basin and is characterized by rich farmland where a variety of crops are grown, including wheat, barley, canola, corn, sunflowers and sugar beets. This SIR-C/X-SAR research site is applying radar remote sensing to study the characteristics of vegetation and soil moisture. The seasonal comparison between the April and October 1994 data show the dramatic differences between surface conditions on the two dates. At the time of the April acquisition, almost all agricultural fields were bare and soil moisture levels were high. In October, however, soils were drier and while most crops had been harvested, some standing vegetation was still present. The areas which are cyan in color are dark in April and bright in October. These represent fields of standing biomass (amount of vegetation in a specified area) and the differences in brightness within these cyan fields represent differences in vegetation type. The very bright fields in October represent standing broadleaf crops such as corn, which had not yet been harvested. Other standing vegetation which has less biomass, such as hay and grain fields, are less bright. The magenta indicates bare soil surfaces which were wetter (brighter) in April than in October. The variations in brightness of

  14. The Northern Manitoba Mining Academy

    Science.gov (United States)

    Alexandre, Paul

    2017-04-01

    The Northern Manitoba Mining Academy (NMMA, miningacademy.ca) is a new educational institution located in Flin Flon, Manitoba. It is associated with the University College of the North and is specifically intended to serve the needs of the Northern Manitoban communities with regards to job creation by providing training in a variety of mining, construction, and exploration related areas. NMMA's mission is to provide innovative and responsible solutions for the creation of a knowledgeable, skilled, and sustainable workforce within a vibrant, mineral-rich resource industry. It facilitates strategic training initiatives and research activities in order to strengthen the social, economic, and environmental benefits of a robust mining and resources sector. In terms of education, NMMA offers its own programs, mostly short courses in health and safety, courses organized by the University College of the North (wilderness safety, prospecting, and exploration), and courses organized in association with provincial Industries-Based Safety Programs and Associations (a variety of construction-related trades). However, the programming is not limited to those courses already on the syllabus: the Academy operates on open-doors policy and welcomes people with their unique and diverse needs; it prides itself in its ability to tailor or create specific on-demand courses and deliver them locally in the North. The Northern Manitoba Mining Academy also provides access to its world-class facilities for field-based undergraduate courses, as well as graduate students and researchers doing field work. Full sample preparation facilities are offered to students and scientists in all natural and environmental sciences.

  15. Waterfowl production survey for southern Manitoba: 1992

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the Waterfowl Production and Habitat Survey for southern Manitoba during 1992. The primary purpose of the survey is to provide information on...

  16. Genetics Home Reference: Manitoba oculotrichoanal syndrome

    Science.gov (United States)

    ... opening in the wall of the abdomen (an omphalocele ) that allows the abdominal organs to protrude through ... 2 links) GeneReview: Manitoba Oculotrichoanal Syndrome MedlinePlus Encyclopedia: Omphalocele Repair General Information from MedlinePlus (5 links) Diagnostic ...

  17. Outbreaks of influenza?like illness in long?term care facilities in Winnipeg, Canada

    OpenAIRE

    Mahmud, Salaheddin M.; Thompson, Laura H; Nowicki, Deborah L.; Plourde, Pierre J.

    2012-01-01

    Please cite this paper as: Mahmud et?al. (2012) Outbreaks of influenza?like illness in long?term care facilities in Winnipeg, Canada. Influenza and Other Respiratory Viruses 10.1111/irv.12052 Background? Outbreaks of influenza?like illness (ILI) are common in long?term care facilities (LTCFs) and result in significant morbidity and mortality among residents. Objectives? We describe patterns of reported ILI outbreaks in LTCFs in Winnipeg, Canada, and examine LTCF and outbreak characteristics t...

  18. Wave-current induced erosion of cohesive riverbanks in northern Manitoba, Canada

    Directory of Open Access Journals (Sweden)

    N. Kimiaghalam

    2015-03-01

    Full Text Available The field of cohesive soil erosion is still not fully understood, in large part due to the many soil parameters that affect cohesive soil erodibility. This study is focused on two channels, 2-Mile and 8-Mile channels in northern Manitoba, Canada, that were built to connect Lake Winnipeg with Playgreen Lake and Playgreen Lake with Kiskikittogisu Lake, respectively. The banks of the channels consist of clay rich soils and alluvial deposits of layered clay, silts and sands. The study of erosion at the sites is further complicated because the flow-induced erosion is combined with the effects of significant wave action due to the large fetch length on the adjacent lakes, particularly Lake Winnipeg that is the seventh largest lake in North America. The study included three main components: field measurements, laboratory experiments and numerical modelling. Field measurements consisted of soil sampling from the banks and bed of the channels, current measurements and water sampling. Grab soil samples were used to measure the essential physical and electrochemical properties of the riverbanks, and standard ASTM Shelby tube samples were used to estimate the critical shear stress and erodibility of the soil samples using an erosion measurement device (EMD. Water samples were taken to estimate the sediment concentration profile and also to monitor changes in sediment concentration along the channels over time. An Acoustic Doppler Current Profiler (ADCP was used to collect bathymetry and current data, and two water level gauges have been installed to record water levels at the entrance and outlet of the channels. The MIKE 21 NSW model was used to simulate waves using historical winds and measured bathymetry of the channels and lakes. Finally, results from the wave numerical model, laboratory tests and current measurement were used to estimate the effect of each component on erodibility of the cohesive banks.

  19. An online nursing leadership literature centre at the University of Manitoba Health Sciences Libraries.

    Science.gov (United States)

    Barrett, Patricia

    2009-09-01

    Decades of hospital restructuring in Canada resulted in significant reductions of nursing leadership positions and altered a nursing infrastructure important for guiding patient care. The importance of acquiring nursing leadership skills to address the negative effects of restructuring is advocated by Canadian nursing bodies. To describe a service innovation for a nursing community. The librarians of the University of Manitoba Health Sciences Libraries (UMHSL) created an online nursing leadership literature centre to support a leadership programme launched by the Nursing Leadership Council (NLC) of the Winnipeg Regional Health Authority. The article will contribute to the body of literature about health library services for nurses. The creation of the service is described. A literature search was undertaken to determine what services have been implemented by librarians for nursing leadership programmes, as well as to review the literature with regard to contributions made by librarians for nursing communities. The literature service, comprised of 19 webliographies based on the NLC's leadership topics, is available on the UMHSL website. A webliography, by definition, is a list of electronic works relating to a particular topic. The NLC created its own website that provides nurses with a means to identify, enhance and evaluate leadership competencies, and which is linked to the UMHSL website. The contributions of the UMHSL librarians to this project support the goals of instilling leadership skills in nurses, encouraging evidence-based nursing practice, and transforming a practice environment to meet the ultimate goal of effective patient care.

  20. The Erosion of University Autonomy in Manitoba

    Science.gov (United States)

    Smith, Dan

    2014-01-01

    Examining legislative change between 1997 and 2013, and analyzing the governance of Manitoba's post-secondary system using military concepts of strategy, operations, and tactics, this article argues that there has been a trend since 2006 of a general loss of university autonomy in the province. The article finds that changes in public policy in…

  1. Transmissibility of the 1918 pandemic influenza in Montreal and Winnipeg of Canada.

    Science.gov (United States)

    Zhang, Shenghai; Yan, Ping; Winchester, Brian; Wang, Jun

    2010-01-01

    The threat of 2009 pandemic influenza A (H1N1) is still causing widespread public concern. A comprehensive understanding of the epidemiology of 1918 pandemic influenza commonly referred to as the Spanish flu may be helpful in offering insight into control strategies for the new pandemic. We explore how the preparedness for a pandemic at the community and individual level impacts the spread of the virus by comparing the transmissibility of the 1918 Spanish flu in two Canadian cities: Montreal and Winnipeg, bearing in mind that each pandemic is unique and the current one may not follow the pattern of the 1918 outbreak. The historical epidemiological data obtained for Montreal and Winnipeg in Canada is analyzed to estimate the basic reproduction number which is the most important summary measure of transmission potential of the pandemic. The transmissibility of the 1918 pandemic influenza virus in Winnipeg in the fall of 1918 was found to be much lower than in Montreal based on the estimated reproduction number obtained assuming different serial intervals which are the time between onsets of symptoms in an index case and a secondary case. The early preparedness and public health control measures could suggest an explanation for the fact that the number of secondary cases generated by a primary case was significantly reduced in Winnipeg comparing to it in Montreal.

  2. Immigrant families in historical perspective: the experiences of Polish pioneers in Winnipeg, 1896-1919

    Directory of Open Access Journals (Sweden)

    ŁUKASZ ALBAŃSKI

    2017-10-01

    Full Text Available This paper focuses on an early Polish family life in Winnipeg. The family often served as a mechanism to reduce a sense of dislocation and to facilitate immigrants' adaptation. The family was also the primary economic unit. The family relations were affected by gender. Both immigrant men and women found themselves reconsidering traditional roles. Somehow immigration tested their family roles in newways.

  3. Therapeutic landscapes of home: Exploring Indigenous peoples' experiences of a Housing First intervention in Winnipeg.

    Science.gov (United States)

    Alaazi, Dominic A; Masuda, Jeffrey R; Evans, Joshua; Distasio, Jino

    2015-12-01

    In this paper, we explore Indigenous perspectives of culture, place, and health among participants in a landmark Canadian Housing First initiative: At Home/Chez Soi (AHCS) project. Implemented from 2009 to 2013 in Winnipeg and four other Canadian cities, AHCS was a multi-city randomized control trial that sought to test the effectiveness of Housing First as a model for addressing chronic homelessness among people living with mental illnesses. As Winnipeg's homeless population is over 70% Indigenous, significant efforts were made to accommodate the culturally specific health, spiritual, and lifestyle preferences of the project's Indigenous participants. While a daunting challenge from an intervention perspective, Winnipeg's experience also provides a unique opportunity to examine how Indigenous participants' experiences can inform improved housing and mental health policy in Canada. In our study, conducted independently from, but with endorsement of the AHCS project, we utilized a case study approach to explore the experiences of the project's Indigenous participants. Data were collected by means of in-depth qualitative interviews with Indigenous participants (N = 14) and key informant project staff and investigators (N = 6). Our exploratory work demonstrates that despite relative satisfaction with the AHCS intervention, Indigenous peoples' sense of place in the city remains largely disconnected from their housing experiences. We found that structural factors, particularly the shortage of affordable housing and systemic erasure of Indigeneity from the urban sociocultural and political landscape, have adversely impacted Indigenous peoples' sense of place and home. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Towards a Manitoba Hydro boreal woodland caribou strategy: Outcomes from Manitoba Hydro boreal woodland caribou workshop

    Directory of Open Access Journals (Sweden)

    Fiona E. Scurrah

    2012-03-01

    Full Text Available Manitoba Hydro is responsible for the continued supply of energy to meet the needs of the province and is committed to protecting the environment when planning the construction and operation of its facilities. Corporate policy dictates ongoing improvement of Environmental Management Systems (EMS in order to meet or surpass regulatory requirements. Environmental objectives are reviewed annually and programs are modified when necessary to address improvements in environmental performance. Manitoba Hydro plans and constructs major transmission projects throughout northern Manitoba which includes areas occupied by boreal woodland caribou. In recognition of the potential issues associated with hydro transmission construction in boreal caribou range, Manitoba Hydro hosted an expert workshop on May 8, 2007 to provide objective advice in the development of a draft corporate strategy that effectively directs targeted monitoring and research for environmental assessment and mitigation. The workshop focused on assessing the potential threats to boreal woodland caribou from a transmission line construction and operation perspective, and identifying appropriate approaches in site selection and environmental assessment (SSEA and long-term monitoring and research. A total of nine threat categories were reviewed to determine the degree and magnitude of potential effects that may result from transmission construction and operation; and of the original nine, five final threat categories were delineated. The main elements of the workshop provided strategic approaches for proactive pre-construction monitoring, research on recruitment and mortality for local populations impacted by ROWs and control areas, and various habitat monitoring, management, and mitigation techniques. Research and monitoring priorities have been identified and continued collaboration with Manitoba Conservation and other land users were also identified.

  5. The Mountain of Health: The Perceptions and Perceived Expectations of Youth Living with Type 2 Diabetes in Winnipeg, Manitoba, Canada, Through a Grounded Theory Study.

    Science.gov (United States)

    Huynh, Elizabeth

    2017-11-08

    The objective of this study was to explore youth's perceptions of diabetes management. The study included 8 Manitoban youth with type 2 diabetes (n=7 girls). Each youth participated in a semistructured interview in person, via Skype or over the phone. The constructivist grounded theory methodologic approach guided the analysis of the data. Discussions about diabetes and health and its management revealed 2 viewpoints: 1) youth's perceptions and 2) youth's perceptions of health-care providers' expectations. The Mountain of Health was used to conceptualize the complex nature of diabetes management. Youth perceived that health-care providers prioritized physical health-behaviour changes in order to achieve successful diabetes management. Conflictingly, many youth described their mental and emotional health as taking precedence over their physical health. Future interventionists should be aware of the vast incongruence in patients' perceptions of health in type 2 diabetes and their perceptions of health-care providers' expectations during the development of interventions. Copyright © 2017 Diabetes Canada. Published by Elsevier Inc. All rights reserved.

  6. Canadian Mathematics Education Study Group = Groupe Canadien d'etude en didactique des mathematiques. Proceedings of the Annual Meeting (Winnipeg, Manitoba, Canada, June 2-6, 1988).

    Science.gov (United States)

    Pereira-Mendoza, Lionel, Ed.

    These conference proceedings include two invited lectures, four working group reports, seven reports from topic groups, one ad hoc presentation paper, a list of participants and a list of previous proceedings. The invited lectures were: "Mathematics Education and Technology" (Christine Keital); and "All One System" (Lynn A.…

  7. Patient and caregiver perspectives of health provision practices for First Nations and M?tis women with gestational diabetes mellitus accessing care in Winnipeg, Manitoba

    National Research Council Canada - National Science Library

    Tait Neufeld, Hannah

    2014-01-01

    ...?s understandings of GDM in an effort to develop appropriate and effective health strategies. A qualitative investigation was conducted to describe the experiences of First Nations and M?tis women with GDM...

  8. Survival

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — These data provide information on the survival of California red-legged frogs in a unique ecosystem to better conserve this threatened species while restoring...

  9. Medio ambiente y comercio: El caso de Mercosur y los principios de Winnipeg

    OpenAIRE

    Konrad von Moltke; Daniel E. Ryan; Sheila Abed de Zavala; Diego Escuder Leira; Carlos Eduardo Frickmann Young; Carlos Galperín; Héctor Ricardo Leis; Patricia I. Vásquez; Eduardo Viola

    2001-01-01

    El propósito del presente trabajo es identificar aquellas iniciativas promisorias que puedan fortalecer la protección del ambiente y la promoción del desarrollo sostenible en el proceso de integración regional, usando de los principios de Winnipeg como marco de referencia. Para tal fin se realizaron una serie de trabajos tendientes a evaluar y analizar la presencia de cada uno estos principios en el Mercosur, así como otros temas específicos que surgen en un marco comparativo más amplio con l...

  10. COUNTRY OF ORIGIN LABELING: IMPLICATIONS FOR THE MANITOBA HOG INDUSTRY

    OpenAIRE

    Grier, Kevin; Martin, Larry J.; Mayer, Holly

    2002-01-01

    This project was undertaken at the request of the Manitoba Pork Council in order to assess the impact of the Country Of Origin Labeling (COL) provisions of the US Farm Bill. The Council needs to know the consequences (economic and otherwise) of COL upon Manitoba hog farmers. The Farm Security and Rural Investment Act of 2002 (the Farm Bill) contains a provision that requires the United States Department of Agriculture (USDA) to issue country of origin labeling guidelines for voluntary use by ...

  11. Outbreaks of influenza-like illness in long-term care facilities in Winnipeg, Canada.

    Science.gov (United States)

    Mahmud, Salaheddin M; Thompson, Laura H; Nowicki, Deborah L; Plourde, Pierre J

    2013-11-01

    Outbreaks of influenza-like illness (ILI) are common in long-term care facilities (LTCFs) and result in significant morbidity and mortality among residents. We describe patterns of reported ILI outbreaks in LTCFs in Winnipeg, Canada, and examine LTCF and outbreak characteristics that influence the clinical outcomes of these outbreaks. We analyzed the electronic records of all ILI outbreaks reported by LTCFs in Winnipeg from 2003 to 2011. Outbreak duration, ILI attack rates among staff and residents, and residents' death rates were calculated by presumed viral etiology, staff vaccination rates, type of influenza chemoprophylaxis used, and time to notification to public health. Of a total of 154 reported outbreaks, most (N=80) were attributed to influenza, and these outbreaks tended to have higher attack and death rates among LTCF residents compared with outbreaks caused by other respiratory viruses (12) or those of unknown etiology (62). About 92% of residents and 38% of staff of the average LTCFs were vaccinated. Chemoprophylaxis was used in 57·5% of influenza outbreaks. Regardless of presumed viral etiology, outbreaks reported within 3 days of onset ended sooner and had lower attack and mortality rates among residents. Influenza-like illness outbreaks still occur among highly immunized LTCF residents, so in addition to vaccination of staff and residents, it is important to maintain competent infection control practices. Early identification and notification to public health authorities and possibly early initiation of control measures could improve clinical outcomes of ILI outbreaks. © 2012 John Wiley & Sons Ltd.

  12. THE 'FROZEN' HEART OF THE CONTINENT: PLACE-BRANDING WINNIPEG IN CANADIAN CRIME FILMS

    Directory of Open Access Journals (Sweden)

    James Gacek

    2016-08-01

    Full Text Available Brands play an imperative role when representing places, as culture and the people who live and create it are at the core of the brand. Aside from promoting experiences and destinations, place brands enhance culture and identity, and orchestrate space and atmosphere to create a particular ambiance in which societies are immersed. Over the past century, the representation of Canada in fictional film has generally emphasized its northerly location, its imagined wilderness landscape, and inevitably, its harsh winter climate. For films that focus on crime, justice is frequently imagined along the lines of the cinematic western, with frontier lawmen bringing order and the reach of the state to remote frontier outposts. For much of the twentieth century, this cultural depiction of Winnipeg justice remained frozen and unchallenged. However, beginning in the latter decades of the twentieth century, a growing number of independent Canadian crime films have taken up these familiar Hollywood tropes in ways that reflect, refract, and sometimes challenge the dominant construction of crime and justice. I examine how these films construct crime and the places that foster crime by emphasizing aspects of racialized identity, class, and the branding dynamics of the city of Winnipeg. Far from the rugged northwest of mid-century Hollywood cinema, crime is relocated to the contemporary city, and while still shaped by the endless Canadian winter, justice is frequently fraught, and the power of law and order distant and unable to extend the civilizing effects of the state to these new urban frontiers.

  13. Barriers, motivators and facilitators related to prenatal care utilization among inner-city women in Winnipeg, Canada: a case-control study.

    Science.gov (United States)

    Heaman, Maureen I; Moffatt, Michael; Elliott, Lawrence; Sword, Wendy; Helewa, Michael E; Morris, Heather; Gregory, Patricia; Tjaden, Lynda; Cook, Catherine

    2014-07-15

    The reasons why women do not obtain prenatal care even when it is available and accessible are complex. Despite Canada's universally funded health care system, use of prenatal care varies widely across neighborhoods in Winnipeg, Manitoba, with the highest rates of inadequate prenatal care found in eight inner-city neighborhoods. The purpose of this study was to identify barriers, motivators and facilitators related to use of prenatal care among women living in these inner-city neighborhoods. We conducted a case-control study with 202 cases (inadequate prenatal care) and 406 controls (adequate prenatal care), frequency matched 1:2 by neighborhood. Women were recruited during their postpartum hospital stay, and were interviewed using a structured questionnaire. Stratified analyses of barriers and motivators associated with inadequate prenatal care were conducted, and the Mantel-Haenszel common odds ratio (OR) was reported when the results were homogeneous across neighborhoods. Chi square analysis was used to test for differences in proportions of cases and controls reporting facilitators that would have helped them get more prenatal care. Of the 39 barriers assessed, 35 significantly increased the odds of inadequate prenatal care for inner-city women. Psychosocial issues that increased the likelihood of inadequate prenatal care included being under stress, having family problems, feeling depressed, "not thinking straight", and being worried that the baby would be apprehended by the child welfare agency. Structural barriers included not knowing where to get prenatal care, having a long wait to get an appointment, and having problems with child care or transportation. Attitudinal barriers included not planning or knowing about the pregnancy, thinking of having an abortion, and believing they did not need prenatal care. Of the 10 motivators assessed, four had a protective effect, such as the desire to learn how to protect one's health. Receiving incentives and getting

  14. Food deserts in Winnipeg, Canada: a novel method for measuring a complex and contested construct

    Directory of Open Access Journals (Sweden)

    Joyce Slater

    2017-10-01

    Full Text Available Introduction: "Food deserts" have emerged over the past 20 years as spaces of concern for communities, public health authorities and researchers because of their potential negative impact on dietary quality and subsequent health outcomes. Food deserts are residential geographic spaces, typically in urban settings, where low-income residents have limited or no access to retail food establishments with sufficient variety at affordable cost. Research on food deserts presents methodological challenges including retail food store identification and classification, identification of low-income populations, and transportation and proximity metrics. Furthermore, the complex methods often used in food desert research can be difficult to reproduce and communicate to key stakeholders. To address these challenges, this study sought to demonstrate the feasibility of implementing a simple and reproducible method of identifying food deserts using data easily available in the Canadian context. Methods: This study was conducted in Winnipeg, Canada in 2014. Food retail establishments were identified from Yellow Pages and verified by public health dietitians. We calculated two scenarios of food deserts based on location of the lowest-income quintile population: (a living ≥ 500 m from a national chain grocery store, or (b living ≥ 500 m from a national chain grocery store or a full-service grocery store. Results: The number of low-income residents living in a food desert ranged from 64 574 to 104 335, depending on the scenario used. Conclusion: This study shows that food deserts affect a significant proportion of the Winnipeg population, and while concentrated in the urban core, exist in suburban neighbourhoods also. The methods utilized represent an accessible and transparent, reproducible process for identifying food deserts. These methods can be used for costeffective, periodic surveillance and meaningful engagement with communities, retailers and policy

  15. Food deserts in Winnipeg, Canada: a novel method for measuring a complex and contested construct.

    Science.gov (United States)

    Slater, Joyce; Epp-Koop, Stefan; Jakilazek, Megan; Green, Chris

    2017-10-01

    "Food deserts" have emerged over the past 20 years as spaces of concern for communities, public health authorities and researchers because of their potential negative impact on dietary quality and subsequent health outcomes. Food deserts are residential geographic spaces, typically in urban settings, where low-income residents have limited or no access to retail food establishments with sufficient variety at affordable cost. Research on food deserts presents methodological challenges including retail food store identification and classification, identification of low-income populations, and transportation and proximity metrics. Furthermore, the complex methods often used in food desert research can be difficult to reproduce and communicate to key stakeholders. To address these challenges, this study sought to demonstrate the feasibility of implementing a simple and reproducible method of identifying food deserts using data easily available in the Canadian context. This study was conducted in Winnipeg, Canada in 2014. Food retail establishments were identified from Yellow Pages and verified by public health dietitians. We calculated two scenarios of food deserts based on location of the lowest-income quintile population: (a) living ≥ 500 m from a national chain grocery store, or (b) living ≥ 500 m from a national chain grocery store or a full-service grocery store. The number of low-income residents living in a food desert ranged from 64 574 to 104 335, depending on the scenario used. This study shows that food deserts affect a significant proportion of the Winnipeg population, and while concentrated in the urban core, exist in suburban neighbourhoods also. The methods utilized represent an accessible and transparent, reproducible process for identifying food deserts. These methods can be used for costeffective, periodic surveillance and meaningful engagement with communities, retailers and policy makers.

  16. Geophysical delineation of acidity and salinity in the Central Manitoba gold mine tailings pile, Manitoba, Canada

    Science.gov (United States)

    Tycholiz, C.; Ferguson, I. J.; Sherriff, B. L.; Cordeiro, M.; Sri Ranjan, R.; Pérez-Flores, M. A.

    2016-08-01

    Surface electrical and electromagnetic geophysical methods can map enhanced electrical conductivity caused by acid mine drainage in mine tailings piles. In this case study, we investigate quantitative relationships between geophysical responses and the electrical conductivity, acidity and salinity of tailing samples at the Central Manitoba Mine tailings in Manitoba, Canada. Previous electromagnetic surveys at the site identified zones of enhanced conductivity that were hypothesized to be caused by acid mine drainage. In the present study, high-resolution EM31 and DC-resistivity measurements were made on a profile through a zone of enhanced conductivity and laboratory measurements of salinity and pH were made on saturation paste extracts from an array of tailing samples collected from the upper 2 m of tailings along the profile. Observed spatial correlation of pH and pore-fluid salinity in the tailings samples confirms that the enhanced conductivity in the Central Manitoba Mine tailings is due to acid mine drainage. Contoured cross-sections of the data indicate that the acid mine drainage is concentrated near the base of the oxidized zone in the thicker parts of the tailings pile. The zone of increased acidity extends to the surface on sloping margins causing an increase in apparent conductivity in shallow penetrating geophysical responses. The quantitative relationship between measured pH and salinity shows that the conductivity increase associated with the acid mine drainage is due only in part to conduction by ions produced from dissociation of sulfuric acid. Comparison of the observations with fluid conductivity estimates based on statistical relationships of pH and ion concentrations in water samples from across the tailings pile shows that Ca2 + and Mg2 + ions also make significant contributions to the conductivity at all values of pH and Cu2 +, Al3 + and Fe3 + ions make additional contributions at low pH. Variability in the measured conductivity at constant

  17. Perceptions of barriers, facilitators and motivators related to use of prenatal care: A qualitative descriptive study of inner-city women in Winnipeg, Canada

    National Research Council Canada - National Science Library

    Heaman, Maureen I; Sword, Wendy; Elliott, Lawrence; Moffatt, Michael; Helewa, Michael E; Morris, Heather; Tjaden, Lynda; Gregory, Patricia; Cook, Catherine

    2015-01-01

    Objective: The objective of this qualitative descriptive study was to explore the perceptions of women living in inner-city Winnipeg, Canada, about barriers, facilitators, and motivators related to their use of prenatal care. Methods...

  18. Characteristics of six recent animal hoarding cases in Manitoba

    OpenAIRE

    Reinisch, Amanda I.

    2009-01-01

    Six recent cases of animal hoarding in Manitoba were compared to the relevant literature. Cases were similar to previous reports in age and demographics of hoarders. Five cases involved small mammals and 1 case involved horses. Understanding this phenomenon would be enhanced by consistent investigative format and reporting and closer working relationships with public health.

  19. VALUE CHAIN AND SWOT ANALYSIS OF THE MANITOBA ...

    African Journals Online (AJOL)

    babatunde Nuga

    orders and regulations are set in place to control the marketing of potatoes produced in. Manitoba. This regulations serves to protect the producers, and also manage the issues related to surplus. Presently, Peak of the Market has agreed with the processing associations to act as agent to sell surplus potatoes destined for ...

  20. Educational Needs and Barriers for African Refugee Students in Manitoba

    Science.gov (United States)

    Kanu, Yatta

    2008-01-01

    This study investigated the educational needs and barriers for diverse African refugee students in two inner-city high schools in Manitoba. Forty African refugee students, two principals, eight teachers, four parents, and four community leaders participated in the study. Five focus groups, individual interviews, and school and classroom…

  1. Manitoba Health's emerging work on wildland fire smoke

    Science.gov (United States)

    Jeffrey Joaquin; Darlene Oshanski

    2015-01-01

    Smoke caused by wildland fire events is an important public health issue, involving major risks to the health of people and the environment. Smoke from wildland fires can travel hundreds of kilometers, affecting air quality far from the flames. Through a partnership with Health Canada, Manitoba Health's Office of Disaster Management (ODM) has undertaken a number...

  2. Stable isotope assessment of water quality, primary productivity, nutrient sources, and food web structure in Lake Winnipeg

    Science.gov (United States)

    Wassenaar, L. I.

    2008-12-01

    Lake Winnipeg (Canada) is a shallow great lake currently undergoing extensive eutrophication. A 4-year stable isotope project is currently underway to examine water quality, primary productivity, nutrient sources, and food web structure in the lake. The isotope hydrology (18O, 2H) of Lake Winnipeg is needed in order to gain a picture of spatial isotopic patterns in the lake that can be related to the unique fingerprints imposed by contributing watersheds, and to verify hydrodynmamic mixing models. Stable isotope assays of key nutrients (nitrate, phosphate), particulate organic matter (POM), and dissolved oxygen in Lake Winnipeg are being applied to assess (1) the sources of nutrients, (2) the sources of the organic matter (internal vs external), (3) the biogeochemical cycling of nutrients and organic matter that lead to algal formation and enhanced biological oxygen demand and 4) quantify the rates of aquatic photoautotrophic activity, respiration and gas exchange. Altogether, these assays will allow us to better link nutrient sources and cycling to enhanced aquatic productivity. Foodweb structure and function is being examined using 13C and 15N while DH and 34S are being evaluated as tracer of inter basin fish migration. Only if the current foodweb structure is well understood can predictions regarding the negative impacts of eutrophication and invasive species on the foodweb be possible.

  3. Prevalence of early childhood caries in 4 Manitoba communities.

    Science.gov (United States)

    Schroth, Robert J; Moore, Pattie; Brothwell, Douglas J

    2005-09-01

    Early childhood caries (ECC) is a particularly destructive form of tooth decay that afflicts young children. Although few prevalence data have been published for Manitoba, long waiting lists for treatment of ECC in hospital indicate that many children in the province suffer from this condition. The purpose of this investigation was to determine the prevalence of ECC and the oral health status of children under 6 years of age in 4 communities in Manitoba and to identify risk factors associated with ECC. The 4 Manitoba communities were selected according to the best available data regarding the number of young children scheduled for dental treatment under general anesthesia. Two of the communities were located in the southern region of the province, and the other 2 were northern communities. In each region, one community represented a disadvantaged population in a large urban centre, whereas the other was a First Nations (on-reserve) community. The parent or guardian (primary caregiver) of each child under 6 years of age was invited to participate. After informed consent had been obtained from the caregiver, each child underwent a dental examination of the deciduous dentition, and the caregiver completed a retrospective questionnaire by interview. A total of 408 children and their caregivers participated in the study. The overall prevalence of ECC was 53.7%, and the prevalence was similar in all 4 communities, with no statistically significant difference in caries between the high-risk urban communities and the First Nations (on-reserve) communities. The mean number of decayed, extracted or filled teeth +/- standard deviation was 4.2 +/- 5.0. Older children were more likely to have ECC (p 0.05). Children with ECC also exhibited more plaque (p < 0.001). The results of this study indicate that ECC is a serious problem in Manitoba. In addition, this investigation establishes a baseline to help evaluate the effectiveness of current and future prevention initiatives in

  4. Demography of a breeding population of whimbrel (Numenius phaeopus) near Churchill, Manitoba, Canada

    Science.gov (United States)

    Perz, Johanna

    I used a GIS raster layer of an area in the Churchill, Manitoba region to investigate the effect of breeding habitat on demography and density of Whimbrel from 2010 through 2013. Program MARK was used to quantify adult and daily nest survival. Apparent annual survival of 0.73 +/- 0.06 SE (95% CI = 0.60-0.83) did not significantly differ between sexes or habitats and was lower than expected based on longevity records and estimates for other large-bodied shorebirds. Nest success, corrected for exposure days, was highly variable, ranging from a low of 3% (95% CI = 0-12%) in 2011 to a high of 71% (95% CI = 54-83%) in 2013. The highest rate of nest survival occurred in the spring with the warmest mean temperature. I developed a generalized linear model (GLM) with a negative-binomial distribution from random plots that were surveyed for abundance to extrapolate a local breeding population size of 410 +/- 230 SE and density of 3.2 birds per square km +/- 1.8 SE. The result of my study suggests that other aspects of habitat not captured by the land cover categories may be more important to population dynamics.

  5. Petroleum investment opportunities in Manitoba - a geological, engineering and economic perspective

    Energy Technology Data Exchange (ETDEWEB)

    Fox, J. N.; Martiniuk, C. D.

    1997-01-01

    Geology and reservoir characteristics of Manitoba`s producing horizons were described, and recent activity in exploration and development prospects for the immediate future were reviewed. These prospects have improved considerably, thanks to recent efforts of the Manitoba Department of Energy and Mines to ensure that barriers to petroleum investment are eliminated. As a result of these and related efforts by the Manitoba government the investment climate is stable and competitive. Advantages in Manitoba include availability of Crown land at comparatively low prices, drilling and exploration incentives, low drilling and completion costs, and easy access to markets. Development drilling opportunities exist for each of Manitoba`s five producing formations (the sandstones of the Jurassic Melita and Amaranth formations, and the Mississippian Bakken Formation, and the carbonates of the Mississipian Lodgepole and Mission Canyon formations). Sample economic scenarios run on three development scenarios and modelled after typical Manitoba oil play were very favorable, indicating a potential rate of return on investments of 25 to 37 per cent and pay-out in 2.6 to 3.2 years. 10 refs., 7 tabs., 5 figs.

  6. Understanding parenting in Manitoba First nations: implications for program development.

    Science.gov (United States)

    Eni, Rachel; Rowe, Gladys

    2011-01-01

    This qualitative study introduced the "Manitoba First Nation Strengthening Families Maternal Child Health Pilot Project" program and evaluation methodologies. The study provided a knowledge base for programmers, evaluators, and communities to develop relevant health promotion, prevention, and intervention programming to assist in meeting health needs of pregnant women and young families. Sixty-five open-ended, semistructured interviews were completed in 13 communities. Data analysis was through grounded theory. Three major themes emerged from the data: interpersonal support and relationships; socioeconomic factors; and community initiatives. Complex structural, historical events compromise parenting; capacity and resilience are supported through informal and formal health and social supports.

  7. Pandemic (H1N1) 2009 influenza in hospitalized children in Manitoba: nosocomial transmission and lessons learned from the first wave.

    Science.gov (United States)

    Fanella, Sergio T; Pinto, Michelle A; Bridger, Natalie A; Bullard, Jared M P; Coombs, Jennifer M L; Crockett, Maryanne E; Olekson, Karen L; Poliquin, Philippe G; Van Caeseele, Paul G; Embree, Joanne E

    2011-05-01

    To review the experiences at Winnipeg Children's Hospital (WCH) during the 2009 influenza season, with an emphasis on nosocomial transmission and infection prevention and control responses. A case series of patients admitted to WCH who had laboratory-confirmed cases of influenza between January 1 and July 31, 2009, with a comparison of patients with seasonal influenza and those with pandemic (H1N1) 2009 influenza; a review of the impact of infection prevention and control modifications on nosocomial transmission. A total of 104 inpatients with influenza, 81 of whom had pandemic (H1N1) 2009 influenza, were reviewed at a large Canadian pediatric tertiary care center. There were no differences in risk factors, presentation, or outcome between patients with seasonal influenza and those with pandemic (H1N1) 2009 influenza. There were 8 nosocomial cases of pandemic (H1N1) 2009 influenza. Excluding patients with nosocomial cases, mean length of hospital stay was significantly shortened to 3.7 days for individuals who had pandemic (H1N1) 2009 influenza and who received empiric oseltamivir on admission to the hospital, compared with 12.0 days for patients for whom treatment was delayed (P = .02). Treatment with oseltamivir of all patients with suspected cases of influenza and prompt modifications to infection control practices, including playroom closures and enhanced education of visitors and staff, terminated nosocomial transmission. Infection with pandemic (H1N1) 2009 influenza virus resulted in a substantial number of hospitalizations of pediatric patients in Manitoba, including those with nosocomial cases, thereby stressing the capacity of WCH. Immediate therapy with oseltamivir on admission to the hospital resulted in a significantly reduced length of hospitalization. This, coupled with intensified infection prevention and control practices, halted nosocomial transmission. These strategies should be considered in future pandemic influenza or other respiratory viral

  8. Management of hydro-biogeochemical connectivity of geographically isolated wetlands to reduce the risk of eutrophication of Lake Winnipeg

    Science.gov (United States)

    Creed, Irena F.; Ameli, Ali

    2017-04-01

    Lake Winnipeg - a transboundary water resource that is the 10th largest freshwater lake in the world - was recently listed as the most threatened lake in the world due to eutrophication. Its watershed has experienced amongst the highest geographically isolated wetland (GIW) drainage rates in the world, leading to increased nutrient loads to remaining wetlands and downstream streams and lakes. GIWs are surrounded by uplands - and thus collect and store water from the surrounding landscape during snowmelt or storm events, and filter nutrients before slowly returning water to the water cycle. When drained, GIWs become connected to downstream flows and nutrients move unimpeded from and through them to downstream waters. Therefore, effective GIW management strategies can reduce nutrient loads to regional surface water bodies in the Lake Winnipeg watershed. But, how do we prioritize wetland protection and restoration efforts? We know that hydrologic connections to GIWs vary in length and timing, and hypothesize that long and slow hydrologic connections to a GIW have higher potential for P retention, while short and fast hydrologic connections to a GIW have lower potential for P retention along the flow path, leading to higher P concentrations within the GIW. We test these hypotheses in a watershed that drains into the North Saskatchewan River and ultimately to Lake Winnipeg. Using a novel model that quantifies the continuum of time and length variations of subsurface-surface hydrological connections to each GIW, we explore the relationship between length and time and time of hydrologic connection to a GIW and nutrients in the GIW. We found that GIWs are not always "isolated" islands - rather, they are connected to other surface waters in diverse ways. GIWs with no modeled surface or subsurface hydrological connections had the lowest nutrient concentrations and algal biomass. Recharge GIWs have lower concentrations of nutrients than discharge wetlands. Discharge GIWs with

  9. Validation of the Kidney Failure Risk Equation in Manitoba

    Science.gov (United States)

    Whitlock, Reid H.; Chartier, Mariette; Komenda, Paul; Hingwala, Jay; Rigatto, Claudio; Walld, Randy; Dart, Allison; Tangri, Navdeep

    2017-01-01

    Background: Patients with chronic kidney disease (CKD) are at risk to progress to kidney failure. We previously developed the Kidney Failure Risk Equation (KFRE) to predict progression to kidney failure in patients referred to nephrologists. Objective: The objective of this study was to determine the ability of the KFRE to discriminate which patients will progress to kidney failure in an unreferred population. Design: A retrospective cohort study was conducted using administrative databases. Setting: This study took place in Manitoba, Canada. Measurements: Age, sex, estimated glomerular filtration rate (eGFR), and urine albumin-to-creatinine ratio (ACR) were measured. Methods: We included patients from the Diagnostic Services of Manitoba database with an eGFR <60 mL/min/1.73 m2 and ACR measured between October 2006 and March 2007. Five-year kidney failure risk was predicted using the 4-variable KFRE and compared with treated kidney failure events from the Manitoba Renal Program database. Sensitivity and specificity for KFRE risk thresholds (3% and 10% over 5 years) were compared with eGFR thresholds (30 and 45 mL/min/1.73 m2). Results: Of 1512 included patients, 151 developed kidney failure over the 5-year follow-up period. The 4-variable KFRE showed a superior prognostic discrimination compared with eGFR alone (area under the receiver operating characteristic curve [AUROC] values, 0.90 [95% confidence interval {CI}: 0.88-0.92] for KFRE vs 0.78 [95% CI: 0.74-0.83] for eGFR). At a 3% threshold over 5 years, the KFRE had a sensitivity of 97% and a specificity of 62%. At 10% risk, sensitivity was 86%, and specificity was 80%. Limitations: Only 11.7% of stage 3-5 CKD patients had simultaneous ACR measurement. The KFRE does not account for other indications for referral such as suspected glomerulonephritis, polycystic kidney disease, and recurrent stone disease. Conclusions: The KFRE has been validated in a population with a demographic and referral profile heretofore

  10. Validation of the Kidney Failure Risk Equation in Manitoba

    Directory of Open Access Journals (Sweden)

    Reid H. Whitlock

    2017-04-01

    Full Text Available Background: Patients with chronic kidney disease (CKD are at risk to progress to kidney failure. We previously developed the Kidney Failure Risk Equation (KFRE to predict progression to kidney failure in patients referred to nephrologists. Objective: The objective of this study was to determine the ability of the KFRE to discriminate which patients will progress to kidney failure in an unreferred population. Design: A retrospective cohort study was conducted using administrative databases. Setting: This study took place in Manitoba, Canada. Measurements: Age, sex, estimated glomerular filtration rate (eGFR, and urine albumin-to-creatinine ratio (ACR were measured. Methods: We included patients from the Diagnostic Services of Manitoba database with an eGFR <60 mL/min/1.73 m2 and ACR measured between October 2006 and March 2007. Five-year kidney failure risk was predicted using the 4-variable KFRE and compared with treated kidney failure events from the Manitoba Renal Program database. Sensitivity and specificity for KFRE risk thresholds (3% and 10% over 5 years were compared with eGFR thresholds (30 and 45 mL/min/1.73 m2. Results: Of 1512 included patients, 151 developed kidney failure over the 5-year follow-up period. The 4-variable KFRE showed a superior prognostic discrimination compared with eGFR alone (area under the receiver operating characteristic curve [AUROC] values, 0.90 [95% confidence interval {CI}: 0.88-0.92] for KFRE vs 0.78 [95% CI: 0.74-0.83] for eGFR. At a 3% threshold over 5 years, the KFRE had a sensitivity of 97% and a specificity of 62%. At 10% risk, sensitivity was 86%, and specificity was 80%. Limitations: Only 11.7% of stage 3-5 CKD patients had simultaneous ACR measurement. The KFRE does not account for other indications for referral such as suspected glomerulonephritis, polycystic kidney disease, and recurrent stone disease. Conclusions: The KFRE has been validated in a population with a demographic and referral profile

  11. Primary productivity of submerged macrophytes in West Blue Lake, Manitoba

    Energy Technology Data Exchange (ETDEWEB)

    Love, R.J.R.; Robinson, G.G.C.

    1977-01-15

    The productivity of Potamogeton Richardsonii, P. pectinatus, Myriophyllum alterniflorum, Megalodonta Beckii, and Chara vulgaris in West Blue Lake, Manitoba, is reported. Measurements of changes in biomass and assimilation of /sup 14/CO/sub 2/ in random and non-random samples throughout the growing season of 1973 were used. Changes in biomass of P. Richardsonii, M. alterniflorum, M. Beckii, and C. vulgaris determined from random samples compared favorably with those determined from non-random samples. This was not the case for P. pectinatus because of its restricted occurrence. Similarly, measurements of /sup 14/CO/sub 2/ assimilation in random samples of P. Richardsonii, M. alterniflorum, and M. Beckii compared well with non-random samples. Productivity values derived from /sup 14/CO/sub 2/ uptake were far in excess of those attained from biomass changes. Seasonal trends of production and the depth distribution of production are discussed, and macrophyte production is compared with phytoplankton production.

  12. Early childhood caries among Hutterite preschool children in Manitoba, Canada.

    Science.gov (United States)

    Schroth, Robert; Dahl, Pamel; Haque, Mohammad; Kliewer, Eleonore

    2010-01-01

    This study investigated the prevalence of early childhood caries (ECC) among Hutterite preschool children from different colonies in southwestern Manitoba, Canada. Following informed consent from the child's parent, children under 72 months of age underwent a dental screening examination. Approval was granted by the University of Manitoba's Health Research Ethics Board. A total of 66 children with a mean age of 40.1 ± 20.1 months participated. The prevalence of ECC was 53%, while the mean decayed, extracted and filled teeth (deft) score was 2.8 ± 4.0 (range 0-20). A total of 42.4% had severe ECC (S-ECC). There was no difference in prevalence among the 6 participating colonies. Only 15 children had already been to the dentist, with the majority of these visits due to decay or dental pain. Of those, the mean age for a first visit was 2.7 ± 0.6 years. Children with ECC were determined to be significantly older than those who were caries-free (pEarly childhood caries and higher caries rates were associated with lower maternal ratings of their child's dental health. Both ECC and increased deft scores were significantly associated with the number of children in the home. This is the first study to report the prevalence of primary tooth decay in Hutterite children. Rates were comparable with other Canadian data for rural dwelling children. Effective and culturally appropriate prevention and health promotion activities are warranted, including fluoride varnish and early dental visits.

  13. Incident diabetes, hypertension and dyslipidemia in a Manitoba First Nation

    Directory of Open Access Journals (Sweden)

    Natalie D. Riediger

    2015-08-01

    Full Text Available Background: Diabetes and diabetes complications are substantially higher among Canadian First Nations populations compared with the general Canadian population. However, incidence data using detailed individual assessments from a population-based cohort have not been undertaken. Objective: We sought to describe incident diabetes, hypertension and dyslipidemia in a population-based cohort from a Manitoba Ojibway First Nation community. Design: Study data were from 2 diabetes screening studies in Sandy Bay First Nation in Manitoba, Canada, collected in 2002/2003 and 2011/2012. The cohort comprised of respondents to both screening studies (n=171. Health and demographic data were collected using a questionnaire. Fasting blood samples, blood pressure and anthropometric data were also collected objectively. Incident diabetes, hypertension and dyslipidemia were determined. Generalized linear models with Poisson distribution were used to estimate risk of incident diabetes and cardiometabolic conditions according to age and sex. Results: There were 35 (95% CI: 26, 45 new cases of diabetes among 128 participants without diabetes at baseline (27 or 3.3% per year. While participants who were 50 years and older at baseline had a significantly higher risk of incident diabetes at follow-up compared with participants aged 18–29 at baseline (p=0.012, more than half of the incident cases of diabetes occurred among participants aged less than 40 at baseline. There were 28 (95% CI: 20, 37 new cases of dyslipidemia at follow-up among 112 without dyslipidemia at baseline (25%. There were 36 (95% CI: 31, 42 new cases of hypertension among 104 participants without hypertension at baseline (34.6%. Women had half the risk of developing hypertension compared with men (p=0.039. Conclusions: Diabetes incidence is very high, and the number of new cases among those younger than 40 is a concern. Additional public health and primary care efforts are needed to address the

  14. BOREAS TGB-05 Fire History of Manitoba 1980 to 1991 in Vector Format

    Data.gov (United States)

    National Aeronautics and Space Administration — Vector format data set covering the province of Manitoba and produced by Forestry Canada from hand-drawn boundaries of fires on photocopies of 1:250,000 scale maps.

  15. BOREAS TGB-05 Fire History of Manitoba 1980 to 1991 in Raster Format

    Data.gov (United States)

    National Aeronautics and Space Administration — Raster format data set covering the province of Manitoba and produced by Forestry Canada from hand-drawn boundaries of fires on photocopies of 1:250,000 scale maps.

  16. BOREAS TGB-05 Fire History of Manitoba 1980 to 1991 in Vector Format

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: Vector format data set covering the province of Manitoba and produced by Forestry Canada from hand-drawn boundaries of fires on photocopies of 1:250,000...

  17. Northern Manitoba, northern Saskatchewan, and the Saskatchewan River Delta: Waterfowl production survey: 1997

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the Waterfowl Production and Habitat Survey for northern Manitoba, northern Saskatchewan, and the Saskatchewan River Delta during 1997. The...

  18. Waterfowl breeding pair survey for southern Manitoba, May 14 through May 31, 1970

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Report of conditions for 1970 for waterfowl production. Survey area was southern Manitoba. Predicted good production year. Most waterfowl numbers up from 1969....

  19. Low Prevalence of VRE Gastrointestinal Colonization of Hospitalized Patients in Manitoba Tertiary Care and Community Hospitals

    Directory of Open Access Journals (Sweden)

    George G Zhanel

    2000-01-01

    Full Text Available OBJECTIVE: To determine the prevalence of vancomycin-resistant enterococci (VRE bowel colonization in hospitalized patients in Manitoba who had stool specimens collected for Clostridium difficile toxin and/or culture testing.

  20. Sciences Humaines Assessment, Manitoba 1991. Final Report: French Immersion Program = Evaluation en sciences humaines, Manitoba 1991. Rapport finale: Programme d'immersion francaise.

    Science.gov (United States)

    Manitoba Dept. of Education and Training, Winnipeg. Curriculum Services Branch.

    This document is the second of two reports of the findings of the 1991 "Sciences...humaines" Assessment for grades 8 and 10 conducted in Franco-Manitoban schools and in French immersion programs in Manitoba, Canada. The report on the French immersion course is presented in parallel French and English versions, and a separate report, in…

  1. Impact of hydroelectric development upon a northern Manitoba native community

    Energy Technology Data Exchange (ETDEWEB)

    Waldram, J.B.

    1983-01-01

    This dissertation describes the process of underdevelopment among the Cree Indian people of South Indian Lake, in Northern Manitoba, Canada, following the construction of the Churchill-Nelson River Hydro Project in 1975. The dissertation seeks to link the ecological, political, economic, socio-cultural and health aspects of the impact of the hydro project within the framework of the historical process of underdevelopment as it has occurred in Latin America, among Native people in the United States, and among Native people in Northern Canada. Utilizing both qualitative and quantitative data, a process of increased dependence is described as the product of two related processes. The first process is the impairment of the local commercial and domestic economy caused by the flooding of Southern Indian Lake, which has resulted in a decline in local productivity. The second process is the enhancement of consumerism through rising consumer expectations and a post-project increase in available goods and services which the people are increasingly unable to afford. The overall result has been a process of economic divergence at the local level. The dissertation concludes that the process of underdevelopment which has occurred in South Indian Lake has been the result primarily of changes in the local ecological system caused by the construction of the hydro project. These ecological changes have, in turn, resulted in secondary changes in the socio-economic system.

  2. Anurans in a Subarctic Tundra Landscape Near Cape Churchill, Manitoba

    Science.gov (United States)

    Reiter, M.E.; Boal, C.W.; Andersen, D.E.

    2008-01-01

    Distribution, abundance, and habitat relationships of anurans inhabiting subarctic regions are poorly understood, and anuran monitoring protocols developed for temperate regions may not be applicable across large roadless areas of northern landscapes. In addition, arctic and subarctic regions of North America are predicted to experience changes in climate and, in some areas, are experiencing habitat alteration due to high rates of herbivory by breeding and migrating waterfowl. To better understand subarctic anuran abundance, distribution, and habitat associations, we conducted anuran calling surveys in the Cape Churchill region of Wapusk National Park, Manitoba, Canada, in 2004 and 2005. We conducted surveys along ~l-km transects distributed across three landscape types (coastal tundra, interior sedge meadow-tundra, and boreal forest-tundra interface) to estimate densities and probabilities of detection of Boreal Chorus Frogs (Pseudacris maculata) and Wood Frogs (Lithobates sylvaticus). We detected a Wood Frog or Boreal Chorus Frog on 22 (87%) of 26 transects surveyed, but probability of detection varied between years and species and among landscape types. Estimated densities of both species increased from the coastal zone inland toward the boreal forest edge. Our results suggest anurans occur across all three landscape types in our study area, but that species-specific spatial patterns exist in their abundances. Considerations for both spatial and temporal variation in abundance and detection probability need to be incorporated into surveys and monitoring programs for subarctic anurans.

  3. Diurnal temperature asymmetries and fog at Churchill, Manitoba

    Science.gov (United States)

    Gough, William A.; He, Dianze

    2015-07-01

    A variety of methods are available to calculate daily mean temperature. We explore how the difference between two commonly used methods provides insight into the local climate of Churchill, Manitoba. In particular, we found that these differences related closely to seasonal fog. A strong statistically significant correlation was found between the fog frequency (hours per day) and the diurnal temperature asymmetries of the surface temperature using the difference between the min/max and 24-h methods of daily temperature calculation. The relationship was particularly strong for winter, spring and summer. Autumn appears to experience the joint effect of fog formation and the radiative effect of snow cover. The results of this study suggests that subtle variations of diurnality of temperature, as measured in the difference of the two mean temperature methods of calculation, may be used as a proxy for fog detection in the Hudson Bay region. These results also provide a cautionary note for the spatial analysis of mean temperatures using data derived from the two different methods particularly in areas that are fog prone.

  4. Variation in the structure of bird nests between northern Manitoba and southeastern Ontario.

    Directory of Open Access Journals (Sweden)

    Carla A Crossman

    Full Text Available Traits that converge in appearance under similar environmental conditions among phylogenetically independent lineages are thought to represent adaptations to local environments. We tested for convergence in nest morphology and composition of birds breeding in two ecologically different locations in Canada: Churchill in northern Manitoba and Elgin in southeastern Ontario. We examined nests from four families of passerine birds (Turdidae: Turdus, Parulidae: Dendroica, Emberizidae: Passerculus and Fringillidae: Carduelis where closely related populations or species breed in both locations. Nests of American Robins, Yellow Warblers, and Carduelis finches had heavier nest masses, and tended to have thicker nest-walls, in northern Manitoba compared with conspecifics or congenerics breeding in southeastern Ontario. Together, all species showed evidence for wider internal and external nest-cup diameters in northern Manitoba, while individual species showed varying patterns for internal nest-cup and external nest depths. American Robins, Yellow Warblers, and Carduelis finches in northern Manitoba achieved heavier nest masses in different ways. American Robins increased all materials in similar proportions, and Yellow Warblers and Common Redpolls used greater amounts of select materials. While changes in nest composition vary uniquely for each species, the pattern of larger nests in northern Manitoba compared to southeastern Ontario in three of our four phylogenetically-independent comparisons suggests that birds are adapting to similar selective pressures between locations.

  5. Transcending jurisdictions: developing partnerships for health in Manitoba First Nation communities.

    Science.gov (United States)

    Eni, Rachel; Phillips-Beck, Wanda

    2011-09-01

    The article describes national, regional and community-level activities that contributed to the Manitoba First Nation partnership in maternal and child health programming. The activities reveal a potential for health change that is possible through working together across jurisdictional boundaries. Although we are only in the early phases of program implementation, the Manitoba First Nation Strengthening Families Maternal Child Health Program already suggests considerable successes and measurable outcomes. The article encourages development of further partnerships in the promotion of First Nation health and wellness programming.

  6. Good Health Is Not the Same as a Good Life: Survey Results from Brandon, Manitoba

    Science.gov (United States)

    Michalos, Alex C.; Ramsey, Douglas; Eberts, Derrek; Kahlke, P. Maurine

    2012-01-01

    The aim of this investigation was to obtain some baseline self-reported data on the health status and overall quality of life of a sample of residents of the city of Brandon, Manitoba aged 18 years or older, and to measure the impact of a set of designated health determinants, comparison standards and satisfaction with diverse domains of life on…

  7. A Population-Based Longitudinal Study of Depression in Children with Developmental Disabilities in Manitoba

    Science.gov (United States)

    Shooshtari, Shahin; Brownell, Marni; Dik, Natalia; Chateau, Dan; Yu, C. T.; Mills, Rosemary S. L.; Burchill, Charles A.; Wetzel, Monika

    2014-01-01

    In this population-based study, prevalence of depression was estimated and compared between children with and without developmental disability (DD). Twelve years of administrative data were linked to identify a cohort of children with DD living in the Canadian province of Manitoba. Children in the study cohort were matched with children without DD…

  8. The Parent-Child Home Program in Western Manitoba: A 20-Year Evaluation

    Science.gov (United States)

    Gfellner, Barbara M.; McLaren, Lorraine; Metcalfe, Arron

    2008-01-01

    This article is a 20-year evaluation of the Parent-Child Home Program (PCHP) of Child and Family Services in Western Manitoba. Following Levenstein's (1979, 1988) approach, home visitors model parent-child interchanges using books and toys to enhance children's cognitive development through appropriate parenting behaviors. The evaluation provides…

  9. Building Interdisciplinary Qualitative Research Networks: Reflections on Qualitative Research Group (QRG) at the University of Manitoba

    Science.gov (United States)

    Roger, Kerstin Stieber; Halas, Gayle

    2012-01-01

    As qualitative research methodologies continue to evolve and develop, both students and experienced researchers are showing greater interest in learning about and developing new approaches. To meet this need, faculty at the University of Manitoba created the Qualitative Research Group (QRG), a community of practice that utilizes experiential…

  10. Children with FASD- Related Disabilities Receiving Services from Child Welfare Agencies in Manitoba

    Science.gov (United States)

    Fuchs, Don; Burnside, Linda; Marchenski, Sheila; Mudry, Andria

    2010-01-01

    Fetal Alcohol Spectrum Disorder (FASD) is a serious social and health problem for the child welfare, health and education systems in North America and other parts of the world. This article describes the population of children in care of the child welfare system in Manitoba. Also this article will highlight the relevance of these research findings…

  11. Greenhouse gas emissions from boreal reservoirs in Manitoba and Quebec, Canada, measured with automated systems.

    Science.gov (United States)

    Demarty, Maud; Bastien, Julie; Tremblay, Alain; Hesslein, Raymond H; Gill, Robert

    2009-12-01

    Growing concern over the contribution of freshwater reservoirs to increases in atmospheric greenhouse gas (GHG) concentrations and the relevance of long-term continuous measurements has led Fisheries and Oceans Canada, in conjunction with Manitoba Hydro, to develop continuous GHG monitors. Continuous water pCO(2), pCH(4), and pO(2) measurements were gathered to estimate gas fluxes in one temperate reservoir (Riviere-des-Prairies) and two boreal reservoirs (Eastmain-1 and Robert-Bourassa) in Quebec, and in four boreal reservoirs (Grand Rapids, Jenpeg, Kettle, and McArthur Falls) in Manitoba, Canada. Mean daily CO(2) fluxes ranged between 7 and 14 mmolCO(2)*m(-2)*d(-1) in Manitoba and between 15 and 55 mmolCO(2)*m(-2)*d(-1) in Quebec. Summertime episodes of water undersaturation in CO(2) were observed at Jenpeg, Kettle, and McArthur, suggesting higher productivities of these systems compared to the other systems studied. Mean daily CH(4) fluxes ranged between 0 and 69 micromolCH(4)*m(-2)*d(-1) in Manitoba and between 9 and 48 micromolCH(4)*m(-2)*d(-1) in Quebec. Comparisons of results obtained in the Eastmain-1 area using automated monitors, floating chambers or dissolved gas analyses over multiple-station field campaigns demonstrated that a continuous GHG monitor at a single sampling station provided representative and robust results.

  12. Governance in Transition: Mothballing Manitoba's Council on Post-Secondary Education

    Science.gov (United States)

    Smith, Dan

    2015-01-01

    Examining the Government of Manitoba decision in 2014 to eliminate the Council on Post-Secondary Education, this article argues that government sought to exercise greater control over the public post-secondary system and its institutions in the province for the purpose of exacting greater control over system integration. While the elimination of…

  13. Ambulatory Care Teaching in Internal Medicine at the University of Manitoba.

    Science.gov (United States)

    Warren, C. P. W.

    1993-01-01

    The University of Manitoba (Canada) medical school is introducing teaching in the ambulatory care setting as traditional inpatient wards become less suitable for clerkships. However, few faculty are willing to accommodate students in their clinics, and other educational and administrative difficulties impede program expansion. (MSE)

  14. 'Perimeteritis' and rural health in Manitoba, Canada: perspectives from rural healthcare managers.

    Science.gov (United States)

    Ramsey, D; Beesley, K B

    2007-01-01

    Rural areas in many parts of the world are facing issues such as economic restructuring, environmental degradation, aging, and depopulation. These issues impact the health and wellbeing of the people living in rural communities. The purpose of this study was to assess rural healthcare managers' understanding of rural community wellbeing. Specifically, definitions were sought for rural, community, health, wellbeing, and healthy rural community. The research reported in this article is based on a set of interviews with each of the 20 healthcare professionals who either managed healthcare centres or administered specialized programs in the rural health care centres in the Assiniboine Regional Health Authority in southwestern Manitoba, Canada. Capitalizing on the open-ended structure of the interviews, respondents were thoughtful and philosophical in their responses. This produced a rich array of definitions of rural, community, health, wellbeing, and healthy rural community. In doing so, the struggles for rural communities in southwestern Manitoba were highlighted. The findings also illustrated that definitions of health and wellbeing do not fit standard biomedical or health determinant models alone. This study was a follow up to another study that employed focus groups to obtain rural resident perceptions of rural, community, wellbeing, and health in southwestern Manitoba. The study reported on here argued that the specific views of healthcare managers were necessary to further illustrate the complexities in understanding definitions of community and condition. The results are consistent with previous research on this topic in southern Manitoba and the recent literature in that there are no universally accepted definitions of rural, community, wellbeing, or health. Further, the study illustrated that professionals charged with managing healthcare services in rural Manitoba maintain very broad definitions of health and wellbeing. Most significantly, the determinants

  15. Northern Manitoba, northern Saskatchewan, and the Saskatchewan River Delta: Waterfowl breeding pair survey: May 9 - June 9, 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the Waterfowl Breeding Population and Habitat Survey for northern Manitoba, northern Saskatchewan, and the Saskatchewan River Delta during...

  16. Manitoba Hydro's Aboriginal partnerships : a new business model for developing current and future hydro-electric projects

    Energy Technology Data Exchange (ETDEWEB)

    Pachal, S.; Goulet, R. [Manitoba Hydro, Winnipeg, MB (Canada)

    2008-07-01

    Socio-economic as well as environmental considerations have become as important as economic factors when developing hydroelectric power projects. Manitoba Hydro has developed a unique partnership approach to deal more effectively and equitably with the Aboriginal communities of Northern Manitoba who live in proximity to, and are affected by, projects such as the construction of the Wuskwatim3, the Keeyask4 and Conawapa5 generating stations. This paper outlined the genesis of Manitoba Hydro's approach along with the main elements and the expected benefits to both Manitoba Hydro and its partners. Their past approach in dealing with the communities who were in the vicinity of hydro-electric projects was also discussed. Manitoba Hydro's new approach includes the provision of training, employment and business opportunities as well as the possibility of ownership in the project. It is not without challenges, as it increases the costs, adds complexity and slows down the planning process. It also requires much consultation and patience to reconcile different goals and priorities regarding the development of these projects. It can also increase the risks involved by increasing construction or operating costs and even impair the viability of projects. Despite the challenges inherent in such partnerships, Manitoba Hydro sees immediate and long-lasting benefits for itself and the communities involved. 16 refs.

  17. A Dutch Fanconi Anemia FANCC Founder Mutation in Canadian Manitoba Mennonites

    Directory of Open Access Journals (Sweden)

    Yne de Vries

    2012-01-01

    Full Text Available Fanconi anemia (FA is a recessive DNA instability disorder associated with developmental abnormalities, bone marrow failure, and a predisposition to cancer. Based on their sensitivity to DNA cross-linking agents, FA cells have been assigned to 15 complementation groups, and the associated genes have been identified. Founder mutations have been found in different FA genes in several populations. The majority of Dutch FA patients belongs to complementation group FA-C. Here, we report 15 patients of Dutch ancestry and a large Canadian Manitoba Mennonite kindred carrying the FANCC c.67delG mutation. Genealogical investigation into the ancestors of the Dutch patients shows that these ancestors lived in four distinct areas in The Netherlands. We also show that the Dutch and Manitoba Mennonite FANCC c.67delG patients share the same haplotype surrounding this mutation, indicating a common founder.

  18. Are Manitoba dentists aware of the recommendation for a first visit to the dentist by age 1 year?

    Science.gov (United States)

    Stijacic, Tijana; Schroth, Robert J; Lawrence, Herenia P

    2008-12-01

    The Canadian Dental Association (CDA) and the American Academy of Pediatric Dentistry (AAPD) recommend that children visit the dentist by 12 months of age. To report on how Manitoba"s general dental practitioners and pediatric dentists manage oral health in early childhood. Mailed surveys that used the modified survey methods of Dillman were sent to 390 Manitoban general dental practitioners and pediatric dentists. The sampling frame was the Manitoba Dental Association"s Membership Registry, but only those dentists who consented to the release of their mailing information were contacted. Survey data were analyzed with Number Cruncher Statistical Software (NCSS 2007). Descriptive statistics, bivariate analyses and multiple regression analyses were done. A p value of dentist; 52.2% (130/249) were unaware of the existence of a standardized case definition for ECC; and 32.3% (80/248) knew that ECC was defined as the presence of at least 1 primary tooth affected by caries in children dentists from Manitoba thought children should visit the dentist by 2 years of age. Although early visits to the dentist are now endorsed by CDA and AAPD, a significant number of dentists in Manitoba are still unaware of the recommendation that children should first visit the dentist by 12 months of age.

  19. Diffusion of personal health information services: self-determining and empowering practices for Manitoba Inuit.

    Science.gov (United States)

    Clark, Wayne Voisey

    2014-01-01

    This article highlights findings from research conducted with the Manitoba Urban Inuit Association with regard to culturally safe practices for communicating personal health information services related to a provincial integrated electronic health record. By applying a "two-eyed seeing research approach," which incorporates traditional and Western scientific perspectives, the author describes Inuit cultural considerations when communicating electronic health concepts with a vision of advancing toward program evaluation opportunities. The research is supported by two Inuit-driven focus groups, interviews with three jurisdictional representatives of electronic health program delivery agencies and one interview with an Inuk elder. Copyright © 2014 Longwoods Publishing.

  20. The bottom line on climate change : a Manitoba business guide : version 1

    Energy Technology Data Exchange (ETDEWEB)

    Swain, A.

    2006-07-15

    Climate changes may pose risks to small businesses by threatening natural resources or capital that many businesses rely on for raw material. In addition, policies on climate change may influence the market to favour less energy-intensive businesses, products and services. Public pressure may also mean that business customers will increasingly prefer climate-friendly products. This guide was created to help small and medium-sized businesses in Manitoba understand the business impacts of climate change. The guide provided resources for businesses to find beneficial and profitable solutions as well as information on how to diversify markets and products. Key benefits of responding to climate change were identified as reduced costs and higher productivity; potential new revenues such as climate-friendly technologies, products and services; enhanced brand image; improved employee morale; and reduced liability and risk. Basic information on climate change in Manitoba was provided, as well as an outline of the easiest ways to save money and reduce greenhouse gas (GHG) emissions. Climate change costs that may affect small businesses were reviewed. Recommendations for negotiating impacts to businesses were also included. A basic climate change plan was presented with a number of provincial resources. Specific resources for different types of small businesses were also provided. 3 tabs.

  1. Changing trends in β-hemolytic streptococcal bacteremia in Manitoba, Canada: 2007-2012.

    Science.gov (United States)

    Schwartz, Ilan Steven; Keynan, Yoav; Gilmour, Matthew W; Dufault, Brenden; Lagacé-Wiens, Philippe

    2014-11-01

    European surveillance studies have reported an increasing incidence of β-hemolytic group G streptococcal bacteremia, but no studies have evaluated trends in β-hemolytic streptococcal bacteremia in North America. We reviewed bacteremic episodes and positive throat swab cultures from two tertiary care centers in Manitoba, Canada, from January 2007 to December 2012. During the study period, 19 864 bacteremic episodes, and 9948 positive throat swabs were identified. There were 1025 (5.16%) bacteremic episodes attributable to β-hemolytic streptococci: 425 (2.03%), 339 (1.71%), 62 (0.31%), and 199 (0.95%) to β-hemolytic groups A, B, C, and G streptococci, respectively. From 2007 to 2012, there were significant increases in the proportion of bacteremia attributable to β-hemolytic streptococci in general (6.32% vs. 4.02%; pstreptococcal groups among throat swabs. Bacteremia attributable to β-hemolytic groups G and C streptococci increased in Manitoba, Canada. Further study of the factors underlying these changes is required.

  2. Biologie 200. French Immersion Program and Franco-Manitoban Schools. Manitoba Science Assessment 1992. Final Report = Biologie 200. Programme d'immersion francaise et ecoles franco-manitobaines. Evaluation en sciences Manitoba 1992. Rapport final.

    Science.gov (United States)

    Manitoba Dept. of Education and Training, Winnipeg. Curriculum Services Branch.

    This report describes the June 1992 assessment of the Biologie 200 curriculum in schools in Manitoba, Canada. It contains a description and analysis of the test results and the teacher survey. The report also includes recommendations on ways to improve the Biologie 200 curriculum and how it is taught in the French Immersion program and…

  3. The Problems of Post-Secondary Education for Manitoba Indians and Metis. Staff Background Paper, January 1973.

    Science.gov (United States)

    Balfour, Margaret

    The standard models of post-secondary education in Manitoba, Canada, historically have not met the special needs and problems of the American Indian and Metis populations. Broadly speaking, the academic qualifications of Canada Natives must be raised to a much higher level in terms of vocational, general, and professional training; thus equipped,…

  4. Outcomes of an investment in administrative data infrastructure: An example of capacity building at the Manitoba Centre for Health Policy.

    Science.gov (United States)

    Orr, Justine; Smith, Mark; Burchill, Charles; Katz, Alan; Fransoo, Randy

    2016-12-27

    Using the Manitoba Centre for Health Policy as an example, this commentary discusses how even small investments in population health data can create a multitude of research benefits. The authors highlight that through infrastructure development such as acquiring databases, facilitating access to data and developing data management practices, new, innovative research can be achieved at relatively low cost.

  5. Holocene evolution of lakes in the forest-tundra biome of northern Manitoba, Canada

    Science.gov (United States)

    Hobbs, William O.; Edlund, Mark B.; Umbanhowar, Charles E.; Camill, Philip; Lynch, Jason A.; Geiss, Christoph; Stefanova, Vania

    2017-03-01

    The late-Quaternary paleoenvironmental history of the western Hudson Bay region of Subarctic Canada is poorly constrained. Here, we present a regional overview of the post-glacial history of eight lakes which span the forest-tundra biome in northern Manitoba. We show that during the penultimate drainage phase of Lake Agassiz the lake water had an estimated pH of ∼6.0, with abundant quillwort (Isöetes spp.) along the lakeshore and littoral zone and some floating green algae (Botryococcus spp. and Pediastrum sp.). Based on multiple sediment proxies, modern lake ontogeny in the region commenced at ∼7500 cal yrs BP. Pioneering diatom communities were shaped by the turbid, higher alkalinity lake waters which were influenced by base cation weathering of the surrounding till following Lake Agassiz drainage. By ∼7000 cal yrs BP, soil development and Picea spp. establish and the lakes began a slow trajectory of acidification over the remaining Holocene epoch. The natural acidification of the lakes in this region is slow, on the order of several millennia for one pH unit. Each of the study lakes exhibit relatively stable aquatic communities during the Holocene Thermal Maximum, suggesting this period is a poor analogue for modern climatic changes. During the Neoglacial, the beginning of the post-Little Ice Age period represents the most significant climatic event to impact the lakes of N. Manitoba. In the context of regional lake histories, the rate of diatom floristic change in the last 200-300 years is unprecedented, with the exception of post-glacial lake ontogeny in some of the lakes. For nearly the entire history of the lakes in this region, there is a strong linkage between landscape development and the aquatic ecosystems; however this relationship appears to become decoupled or less strong in the post-LIA period. Significant 20th century changes in the aquatic ecosystem cannot be explained wholly by changes in the terrestrial ecosystem, suggesting that future

  6. Propanil in a Manitoba soil: an interactive spreadsheet model based on conventional chemical kinetics.

    Science.gov (United States)

    Gamble, Donald S; Webster, G R Barrie; Lamoureux, Marc

    2012-04-01

    An interactive spreadsheet model has been created for quantitative predictions of propanil sorption and reaction in a slurried Manitoba clay soil. Based on experimental values for the numbers of empty and filled sorption sites as reactants and products, the reaction mechanism has been described with conventional chemical kinetics. The on line HPLC μ extraction method revealed labile sorption, intraparticle diffusion, and a chemical reaction. Laidler's integral rate law for second order kinetics describes the labile sorption. Desorption, intraparticle diffusion, and the chemical reaction are all described by first order kinetics. The time dependent effects of initial concentration and amount of slurried soil can be predicted for sorption, intraparticle diffusion, and the amount of reaction product. Suggested applications include storm runoff and inputs for fate and transport hydrology models.

  7. Canopy, snow, and lichens on woodland caribou range in southeastern Manitoba

    Directory of Open Access Journals (Sweden)

    James A. Schaefer

    1996-01-01

    Full Text Available I examined the relationships among snow cover (api, lichen abundance, and canopy composition on the range of the Aikens Lake population of woodland caribou (Rangifer tarandus caribou in southeastern Manitoba. Percent cover of forage lichens (Cladina spp. was positively correlated with maximum total thickness and with maximum vertical hardness of api. Mixed communities of trembling aspen (Populus tremuloides, spruce (Picea spp., and balsam fir (Abies balsamea showed the most favourable nival conditions for caribou but had low lichen abundance; those dominated by jack pine (Pinus banksiana were the converse. The results suggest an energetic compromise for woodland caribou when foraging for terrestrial lichens. During winter, caribou exhibited significant selection for jack pine communities whereas mixed communities were avoided.

  8. Geological controls on soil parent material geochemistry along a northern Manitoba-North Dakota transect

    Science.gov (United States)

    Klassen, R.A.

    2009-01-01

    As a pilot study for mapping the geochemistry of North American soils, samples were collected along two continental transects extending east–west from Virginia to California, and north–south from northern Manitoba to the US–Mexican border and subjected to geochemical and mineralogical analyses. For the northern Manitoba–North Dakota segment of the north–south transect, X-ray diffraction analysis and bivariate relations indicate that geochemical properties of soil parent materials may be interpreted in terms of minerals derived from Shield and clastic sedimentary bedrock, and carbonate sedimentary bedrock terranes. The elements Cu, Zn, Ni, Cr and Ti occur primarily in silicate minerals decomposed by aqua regia, likely phyllosilicates, that preferentially concentrate in clay-sized fractions; Cr and Ti also occur in minerals decomposed only by stronger acid. Physical glacial processes affecting the distribution and concentration of carbonate minerals are significant controls on the variation of trace metal background concentrations.

  9. Does the Manitoba science curriculum help teach teens to be more environmentally-minded?

    Science.gov (United States)

    Kraljevic, Gabriel M.

    Manitoba does not have a specific course in environmental education (EE) but has related outcomes within the current science and social studies curricula. Has the curriculum created a populace with the knowledge, attitudes and skills to begin to act for environmental change? Do students and teachers perceive science to be the course that should teach EE? This mixed-method study used surveys, student focus groups, observations of recycling habits and teacher interviews to determine if grade 10 students (last year of required science) are acting in positive ways toward the environment. Students from grades nine and ten exhibited almost the same environmental knowledge and attitudes, but the grade tens were more alarmed about the state of the environment and less naive about their abilities to have individual impact. While both groups reported pro-environmental behaviours, neither recycled materials after a luncheon. Where EE should be taught differed between all groups studied.

  10. Saskatoon and wild blueberries have higher anthocyanin contents than other Manitoba berries.

    Science.gov (United States)

    Hosseinian, Farah S; Beta, Trust

    2007-12-26

    Studies have shown that anthocyanins present in berry fruits have some beneficial health effects such as reducing age-associated oxidative stress and possessing anti-inflammatory properties. Therefore, six Manitoba berries (wild blueberry, Saskatoon berry, raspberry, chokecherry, strawberry, and seabuckthorn) were studied for their anthocyanin compositions (mg/100 g) on dry weight basis. Saskatoon berry and wild blueberry showed a high content of total anthocyanins (562.4 and 558.3 mg/100 g, respectively) that were not significantly (P>0.05) different from each other. The corresponding values for other berries: raspberry (365.2 mg/100 g), chokecherry (177.39 mg/100 g), and strawberry (97.5 mg/100 g) were significantly different from each other (Pblueberries have high potential value for fruit growers as well as the food and nutraceutical manufacturers because of their high anthocyanin contents.

  11. The Manitoba-Ontario intertie : perspectives of a merchant transmission developer

    Energy Technology Data Exchange (ETDEWEB)

    Van Beers, R. [Tonbridge Power Inc., Toronto, ON (Canada)

    2006-07-01

    This presentation discussed merchant transmission models for the Manitoba-Ontario intertie. Merchant transmission involves the reallocation of risk from rate payers to investors and facility users. Merchant transmission is now a niche market due to the fact that the power industry is now more centrally planned. However, merchant transmission structures limit the ability to fully assess congestion and nodal values, and governments continue to retain control of the power sector. Power generation and contracting trends are now changing as a result of market liberalization. In order to be successful, power merchants require financial markets that possess an understanding of the electricity sector. In a merchant transmission scenario, the sizing, timing, connection points, and tariffs will be determined by demonstrated commercial value, and not by central planning principles. The presentation included consideration of government block contracts and reverse block contracts. Details of the Montana-Alberta intertie project were also provided. tabs., figs.

  12. Déserts alimentaires à Winnipeg (Canada : une nouvelle méthodologie de mesure d'un concept complexe et controversé

    Directory of Open Access Journals (Sweden)

    Joyce Slater

    2017-01-01

    Full Text Available Introduction : Les « déserts alimentaires » ont vu le jour dans les 20 dernières années et forment des secteurs préoccupants pour les collectivités, les autorités en santé publique et les chercheurs en raison de leur effet négatif possible sur la qualité de l’alimentation et en raison de leurs conséquences sur la santé. Ce sont des espaces résidentiels, habituellement en milieu urbain, où les résidents à faible revenu n’ont que peu ou pas accès à des établissements de vente au détail d'aliments qui offrent suffisamment de variété à un prix abordable. La recherche sur les déserts alimentaires présente des défis méthodologiques, notamment la façon de repérer et de classer les magasins d’alimentation au détail, la définition de la population à faible revenu ainsi que les paramètres concernant le transport et la proximité. De plus, les méthodes complexes qui sont souvent employées dans la recherche sur les déserts alimentaires peuvent être difficiles à reproduire et à communiquer aux principaux intervenants. Pour surmonter ces difficultés, nous avons voulu montrer qu’on pouvait concevoir une méthode simple et reproductible pour repérer les déserts alimentaires, à l’aide de données facilement accessibles en contexte canadien. Méthodologie : Cette étude a été menée à Winnipeg (Canada en 2014. Les établissements de vente au détail des aliments ont été trouvés à l’aide des Pages Jaunes et vérifiés par des diététistes en santé publique. Nous avons créé deux scénarios sur les déserts alimentaires en fonction de l’emplacement de la population à quintile de revenu le plus faible : a celle qui habitait à 500 m ou plus d’une épicerie appartenant à une chaîne nationale et b celle qui habitait à 500 m ou plus d’une épicerie appartenant à une chaîne nationale ou d’une épicerie à service complet. Résultats : En fonction du scénario utilisé, 64 574 ou 104 335 r

  13. Oral health in a First Nations and a non-Aboriginal population in Manitoba

    Directory of Open Access Journals (Sweden)

    Shirley Chubey

    2012-03-01

    Full Text Available Objectives: To analyze the prevalence of poor oral health and selected determinants in First Nations (FN and Caucasian samples in Manitoba, Canada. Study design: Cross-sectional survey, nested in a cohort study. Methods: FN and Caucasian participants completed a questionnaire on socio-demographic variables, oral health symptoms, and oral health-related behaviours as part of a broader cohort study comparing these ethnic groups for different chronic immune mediated diseases. Results: Caucasians reported higher levels of employment, education, and urban dwelling than FNs (p<0.001. FNs reported smoking more, and having poorer oral health-related behaviours than Caucasians (p<0.001. After adjustment for age and sex, FN reported having more oral health symptoms than Caucasians (odds ratio (OR: 2.71; 95% confidence interval (CI: 1.73, 4.52, but the association was reduced and not statistically significant after adjustment for other socio-demographic variables (OR=1.34; 95% CI: 0.58, 3.10. Oral health symptoms were associated with current smoking among FN (adjusted OR=2.67, 95% CI: 1.05, 6.78. Oral hygiene behaviours were significantly related to smoking status, rural living and education for both groups. Conclusions: Oral health-related behaviours and smoking were found to be significant factors explaining poor oral health, which were lower for the FNs cohort than the Caucasian sample. However oral health and related behaviours were less related to their ethnicity than to socio-demographic factors, suggesting that policies to change behaviour will not result in lasting reductions in oral health differences between these groups in Manitoba.

  14. Health behaviours associated with indoor tanning based on the 2012/13 Manitoba Youth Health Survey

    Directory of Open Access Journals (Sweden)

    E. Harland

    2016-08-01

    Full Text Available Introduction: Although indoor tanning causes cancer, it remains relatively common among adolescents. Little is known about indoor tanning prevalence and habits in Canada, and even less about associated behaviours. This study explores the prevalence of adolescent indoor tanning in Manitoba and its association with other demographic characteristics and health behaviours. Methods: We conducted secondary analyses of the 2012/13 Manitoba Youth Health Survey data collected from Grade 7 to 12 students (n = 64 174 and examined associations between indoor tanning (whether participants had ever used artificial tanning equipment and 25 variables. Variables with statistically significant associations to indoor tanning were tested for collinearity and grouped based on strong associations. For each group of highly associated variables, the variable with the greatest effect upon indoor tanning was placed into the final logistic regression model. Separate analyses were conducted for males and females to better understand sex-based differences, and analyses were adjusted for age. Results: Overall, 4% of male and 9% of female students reported indoor tanning, and prevalence increased with age. Relationships between indoor tanning and other variables were similar for male and female students. Binary logistic regression models indicated that several variables significantly predicted indoor tanning, including having part-time work, being physically active, engaging in various risk behaviours such as driving after drinking for males and unplanned sex after alcohol/drugs for females, experiencing someone say something bad about one's body shape/size/appearance, identifying as trans or with another gender, consuming creatine/other supplements and, for females only, never/rarely using sun protection. Conclusion: Indoor tanning among adolescents was associated with age, part-time work, physical activity and many consumption behaviours and lifestyle risk factors. Though

  15. Health behaviours associated with indoor tanning based on the 2012/13 Manitoba Youth Health Survey.

    Science.gov (United States)

    Harland, E; Griffith, J; Lu, H; Erickson, T; Magsino, K

    2016-08-01

    Although indoor tanning causes cancer, it remains relatively common among adolescents. Little is known about indoor tanning prevalence and habits in Canada, and even less about associated behaviours. This study explores the prevalence of adolescent indoor tanning in Manitoba and its association with other demographic characteristics and health behaviours. We conducted secondary analyses of the 2012/13 Manitoba Youth Health Survey data collected from Grade 7 to 12 students (n = 64 174) and examined associations between indoor tanning (whether participants had ever used artificial tanning equipment) and 25 variables. Variables with statistically significant associations to indoor tanning were tested for collinearity and grouped based on strong associations. For each group of highly associated variables, the variable with the greatest effect upon indoor tanning was placed into the final logistic regression model. Separate analyses were conducted for males and females to better understand sex-based differences, and analyses were adjusted for age. Overall, 4% of male and 9% of female students reported indoor tanning, and prevalence increased with age. Relationships between indoor tanning and other variables were similar for male and female students. Binary logistic regression models indicated that several variables significantly predicted indoor tanning, including having part-time work, being physically active, engaging in various risk behaviours such as driving after drinking for males and unplanned sex after alcohol/drugs for females, experiencing someone say something bad about one's body shape/size/appearance, identifying as trans or with another gender, consuming creatine/other supplements and, for females only, never/rarely using sun protection. Indoor tanning among adolescents was associated with age, part-time work, physical activity and many consumption behaviours and lifestyle risk factors. Though legislation prohibiting adolescent indoor tanning is critical

  16. Perceptions of barriers, facilitators and motivators related to use of prenatal care: A qualitative descriptive study of inner-city women in Winnipeg, Canada

    Directory of Open Access Journals (Sweden)

    Maureen I Heaman

    2015-12-01

    Full Text Available Objective: The objective of this qualitative descriptive study was to explore the perceptions of women living in inner-city Winnipeg, Canada, about barriers, facilitators, and motivators related to their use of prenatal care. Methods: Individual, semi-structured interviews were conducted in person with 26 pregnant or postpartum women living in inner-city neighborhoods with high rates of inadequate prenatal care. Interviews averaged 67 min in length. Recruitment of participants continued until data saturation was achieved. Inductive content analysis was used to identify themes and subthemes under four broad topics of interest (barriers, facilitators, motivators, and suggestions. Sword’s socio-ecological model of health services use provided the theoretical framework for the research. This model conceptualizes service use as a product of two interacting systems: the personal and situational attributes of potential users and the characteristics of health services. Results: Half of the women in our sample were single and half self-identified as Aboriginal. Participants discussed several personal and system-related barriers affecting use of prenatal care, such as problems with transportation and child care, lack of prenatal care providers, and inaccessible services. Facilitating factors included transportation assistance, convenient location of services, positive care provider qualities, and tangible rewards. Women were motivated to attend prenatal care to gain knowledge and skills and to have a healthy baby. Conclusion: Consistent with the theoretical framework, women’s utilization of prenatal care was a product of two interacting systems, with several barriers related to personal and situational factors affecting women’s lives, while other barriers were related to problems with service delivery and the broader healthcare system. Overcoming barriers to prenatal care and capitalizing on factors that motivate women to seek prenatal care

  17. Determinants of injection drug user (IDU) syringe sharing: the relationship between availability of syringes and risk network member characteristics in Winnipeg, Canada.

    Science.gov (United States)

    Shaw, Souradet Y; Shah, Lena; Jolly, Ann M; Wylie, John L

    2007-10-01

    Despite the establishment of syringe exchange programmes, syringe-sharing behaviour remains common among some injection drug users (IDU). Previous studies have identified several individual- and social network-level variables associated with syringe sharing. We examine the extent to which each of these variables is related independently to this behaviour within a diverse study population. A cross-sectional survey of 435 IDU conducted between December 2003 and September 2004 in Winnipeg, Canada. Individual and social-network variables were obtained from a survey instrument administered through a personal interview. Syringe sharing was defined as receptive syringe sharing in the last 6 months. Logistic regression analysis with generalized estimating equations was used to determine simultaneously the role of individual-level and risk network member-level variables on the odds of syringe sharing. Individuals' relationship to a risk network member (sex partner, OR: 15.3 95% CI: 7.6-30.8; family member, OR: 3.4 95% CI: 1.3-9.0) and difficulty of access to syringes (OR: 3.6 95% CI: 1.3-9.9) were predictive of syringe sharing. Dyads who 'often' pooled resources to obtain drugs were at 4.9 times (95% CI: 2.1-11.6) the odds of syringe sharing, while those who 'sometimes' pooled resources were at 2.8 times (95% CI: 1.1-6.7) the odds, compared to those who 'never' pooled resources together. Syringe sharing in this population depended on both the availability of clean syringes and social network relationships. Adopting interventions that take into account relationships and behaviours that shape social norms present in networks/dyads would be a necessary prevention strategy alongside the provision of clean syringes.

  18. Tobacco use cessation services provided by dentists and dental hygienists in Manitoba: part 1. Influence of practitioner demographics and psychosocial factors

    National Research Council Canada - National Science Library

    Brothwell, Douglas J; Gelskey, Shirley C

    2008-01-01

    .... The purpose of this part of our study was to assess BIC practice patterns among dentists and dental hygienists in Manitoba and to determine whether demographic or psychosocial factors influence BIC delivery...

  19. Does geography influence the treatment and outcomes of colorectal cancer? A population-based analysis.

    Science.gov (United States)

    Helewa, Ramzi M; Turner, Donna; Wirtzfeld, Debrah; Park, Jason; Hochman, David; Czaykowski, Piotr; Singh, Harminder; Shu, Emma; Xue, Lin; McKay, Andrew

    2013-06-17

    The Canadian province of Manitoba covers a large geographical area but only has one major urban center, Winnipeg. We sought to determine if regional differences existed in the quality of colorectal cancer care in a publicly funded health care system. This was a population-based historical cohort analysis of the treatment and outcomes of Manitobans diagnosed with colorectal cancer between 2004 and 2006. Administrative databases were utilized to assess quality of care using published quality indicators. A total of 2,086 patients were diagnosed with stage I to IV colorectal cancer and 42.2% lived outside of Winnipeg. Patients from North Manitoba had a lower odds of undergoing major surgery after controlling for other confounders (odds ratio (OR): 0.48, 95% confidence interval (CI): 0.26 to 0.90). No geographic differences existed in the quality measures of 30-day operative mortality, consultations with oncologists, surveillance colonoscopy, and 5-year survival. However, there was a trend towards lower survival in North Manitoba. We found minimal differences by geography. However, overall compliance with quality measures is low and there are concerning trends in North Manitoba. This study is one of the few to evaluate population-based benchmarks for colorectal cancer therapy in Canada.

  20. Defining fish community structure in Lake Winnipeg using stable isotopes (δ{sup 13}C, δ{sup 15}N, δ{sup 34}S): Implications for monitoring ecological responses and trophodynamics of mercury and other trace elements

    Energy Technology Data Exchange (ETDEWEB)

    Ofukany, Amy F.A. [Toxicology Centre, University of Saskatchewan, 44 Campus Drive, Saskatoon, Saskatchewan S7N 5B3 (Canada); Wassenaar, Leonard I. [Environment Canada, 11 Innovation Boulevard, Saskatoon, Saskatchewan S7N 3H5 (Canada); Bond, Alexander L., E-mail: alex.bond@rspb.org.uk [Environment Canada, 11 Innovation Boulevard, Saskatoon, Saskatchewan S7N 3H5 (Canada); Hobson, Keith A. [Environment Canada, 11 Innovation Boulevard, Saskatoon, Saskatchewan S7N 3H5 (Canada)

    2014-11-01

    The ecological integrity of freshwater lakes is influenced by atmospheric and riverine deposition of contaminants, shoreline development, eutrophication, and the introduction of non-native species. Changes to the trophic structure of Lake Winnipeg, Canada, and consequently, the concentrations of contaminants and trace elements measured in tissues of native fishes, are likely attributed to agricultural runoff from the 977,800 km{sup 2} watershed and the arrival of non-native zooplankters and fishes. We measured δ{sup 13}C, δ{sup 15}N, and δ{sup 34}S along with concentrations of 15 trace elements in 17 native fishes from the north and south basins of Lake Winnipeg in 2009 and 2010. After adjusting for differences in isotopic baseline values between the two basins, fishes in the south basin had consistently higher δ{sup 13}C and δ{sup 34}S, and lower δ{sup 15}N. We found little evidence of biomagnification of trace elements at the community level, but walleye (Sander vitreus) and freshwater drum (Aplodinotus grunniens) had higher mercury and selenium concentrations with increased trophic position, coincident with increased piscivory. There was evidence of growth dilution of cobalt, copper, manganese, molybdenum, thallium, and vanadium, and bioaccumulation of mercury, which could be explained by increases in algal (and consequently, lake and fish) productivity. We conclude that the north and south basins of Lake Winnipeg represent very different communities with different trophic structures and trace element concentrations. - Highlights: • Anthropogenic eutrophication and non-native species affect Lake Winnipeg’s ecosystem. • We measured stable isotopes and trace elements in 15 native fish species. • There was more evidence for growth dilution than biomagnification for most elements. • The trophic structures of the north and south basins were different. • These results will help determine the effects of recent arrival of zebra mussels.

  1. Have investments in on-reserve health services and initiatives promoting community control improved First Nations' health in Manitoba?

    Science.gov (United States)

    Lavoie, Josée Gabrielle; Forget, Evelyn L; Prakash, Tara; Dahl, Matt; Martens, Patricia; O'Neil, John D

    2010-08-01

    The objective of this study was to document the relationship between First Nation's community characteristics and the rates of hospitalization for Ambulatory Care Sensitive Conditions (ACSC) in the province of Manitoba, Canada. A population-based time trend analysis of selected ACSC was conducted using the de-identified administrative data housed at the Manitoba Centre for Health Policy, including vital statistics and health information. The study population included all Manitoba residents eligible under the universal Manitoba Health Services Insurance Plan and living on First Nation reserves between 1984/85 and 2004/05. Twenty-nine ACSC defined using 3, 4 and 5 digit ICD-9-CM and ICD-10-CM codes permitted cross-sectional and longitudinal comparison of hospitalization rates. The analysis used Generalized Estimated Equation (GEE) modeling. Two variables were significant in our model: level of access to primary health care on-reserve; and level of local autonomy. Communities with local access to a broader complement of primary health care services showed a lower rate of hospitalization for ACSC. We also examined whether there was a significant trend in the rates of hospitalization for ACSC over time following the signature of an agreement increasing local autonomy over resource allocation. We found the rates of hospitalization for ACSC decreased with each year following the signature of such an agreement. This article demonstrates that communities with better local access to primary health care consistently show lower rates of ACSC. Secondly, the longer community health services have been under community control, the lower its ACSC rate. (c) 2010 Elsevier Ltd. All rights reserved.

  2. North-South Gradients in Adverse Birth Outcomes for First Nations and Others in Manitoba, Canada

    Science.gov (United States)

    Martens, Patricia J.; Heaman, Maureen; Hart, Lyna; Wilkins, Russell; Smylie, Janet; Wassimi, Spogmai; Simonet, Fabienne; Wu, Yuquan; Fraser, William D.; Luo, Zhong-Cheng

    2012-01-01

    Objective to determine the relationship of north-south place of residence to adverse birth outcomes among First Nations and non-First Nations in Manitoba, Canada, a setting with universal health insurance. Study Design Live birth records (n=151,472) for the province of Manitoba, Canada 1991–2000 were analyzed, including 25,743 First Nations and 125,729 non-First Nations infants. North-south and rural-urban residence was determined for each birth through geocoding. Results Comparing First Nations to non-First Nations, crude rates in North (and South) were: 7.0% versus 8.4% (9.3% versus 7.5%) for preterm birth; 6.1% versus 8.4% (8.7% versus 10.0%) for small-for-gestational-age birth, 4.2% versus 6.5% (6.2% versus 5.7%) for low birth weight, and 20.6% versus 13.7% (17.0% versus 11.0%) for large-for-gestational-age birth; and mortality per 1000 - neonatal 3.2 versus 6.2 (3.8 versus 3.3), post-neonatal 6.4 versus 6.4 (5.8 versus 1.5), and infant 9.5 versus 12.6 (9.6 versus 4.8). Adjusting for observed maternal and infant characteristics and rural versus urban residence, the North was high risk for large-for-gestational-age birth for both First Nations and non-First Nations. First Nations’ risk of preterm, small-for-gestational-age and low birth weight was lowest in the North, but for non-First Nations, the North was lower only for small-for-gestational-age. First Nations mortality indicators were similar North to South, but for non-First Nations, the North was high risk. Conclusion North-South place of residence does matter for adverse birth outcomes, but the effects may differ by ethnicity and could require different intervention strategies. PMID:22523523

  3. Opportunity Cost and Policy: A Utilization Review of Self-monitoring of Blood Glucose in Manitoba, Canada.

    Science.gov (United States)

    Serwylo, Olena; Friesen, Kevin; Falk, Jamie; Bugden, Shawn

    2016-04-01

    Recently, there has been a re-evaluation of the frequency, benefits, and costs associated with self-monitoring of blood glucose (SMBG). Based on little evidence of the benefit of frequent SMBG in patients with diabetes not using insulin, new guidelines and test strip limit policies have been suggested and implemented in various Canadian jurisdictions to promote a more selective practice of SMBG. The objective of this study was to assess the overall utilization and cost associated with test strips and lancets for SMBG in Manitoba from 2000 to 2013 as well as to explore the policy implications of the implementation of test strip quantity limits and its impact on overall and government costs. An analysis of prescription claims for blood glucose test strips (BGTSs) and lancets for all patients with diabetes in Manitoba from 2000 to 2013 was conducted. In each year, patients were stratified into 4 mutually exclusive hierarchical groups according to most intensive diabetes treatment. Test strip and lancet utilization and cost were assessed for each group in each year, and the potential cost savings associated with implementation of a BGTS limit policy was projected using autoregressive integrated moving average models. In the year 2000, 8 million test strips were dispensed in Manitoba, increasing by 170% to 21.7 million test strips in 2013. Insulin users accounted for the majority of test strip use. However, based on potential implementation of test strip limit policies, 95% of the reduction of test strip use is predicted to occur in the groups not using insulin. Based on current trends, the 5-year predicted additional cost associated with not implementing a test strip limit policy similar to that implemented in other Canadian provinces was estimated to be a total of $12.35 million. Implementation of the guideline-based policy limits is predicted to produce considerable savings, with 95% of potential savings occurring in patients not using insulin. There is, therefore, a

  4. Individual and population doses in Manitoba from chiropractic x-ray procedures

    Energy Technology Data Exchange (ETDEWEB)

    Huda, W.; Sourkes, A.M. (Manitoba Cancer Treatment and Research Foundation, Winnipeg, MB (Canada))

    1989-12-01

    Manitoba (population of 1.0 million) has 37 chiropractors who perform x-rays on behalf of 100 practising chiropractors. In 1987 these specialists performed approximately 33 300 spinal x-ray studies. Cervical spine examinations contribute the lowest patient dose (average H{sub E} of 26 {mu}Sv); thoracic and lumbar spine examinations show considerably higher patient dose (H{sub E} in the range 24-410 {mu}Sv) Average patient H{sub E} was determined to be 220 {mu}Sv. Lumbar spine examinations account for 45% of all chiropractic x-ray examinations (84% of the collective dose). Cervical spine examinations also account for 45% of chiropractic x-ray examinations, but contribute only 5% of the collective dose with thoracic spine examinations contributing the 11% balance of the collective dose. Patients undergoing chiropractic procedures involving exposure to x-rays account for about 3.6% of all diagnostic x-ray procedures. The per caput dose contribution from chiropractic practice was calculated to be 7.3 {mu}Sv (1.2% of total population dose from diagnostic procedures employing ionising radiation). (author).

  5. Hydrocarbon potential of the Lower Amaranth M Pool, Waskada Field, southwest Manitoba

    Energy Technology Data Exchange (ETDEWEB)

    Karasinski, D.R.; Last, W.M. [Manitoba Univ., Winnipeg, MB (Canada). Dept. of Geological Science; Martiniuk, C.D. [Manitoba Industry, Economic Development and Mines, Winnipeg, MB (Canada). Petroleum Branch

    2005-07-01

    The major hydrocarbon producer of Manitoba's Waskada Field is the Lower Amaranth Member of the Jurassic Amaranth, the oldest Mesozoic unit in the northeastern portion of the Williston Basin. Reservoir facies occur as sandy intervals on logs, and are complexly interbedded intertidal sandstones and siltstones. Thickness of the Lower Member is controlled by the paleotopography of the underlying Paleozoic erosional surface. Hydrocarbon production in the Waskada Amaranth began in 1980 with the recompletion of a former Mississippian producer. In the mid-1990s, the Waskada Field expanded eastward into the Goodlands area, with the development of the Lower Amaranth M pool. Developed original oil in place (OOIP) is calculated to be 9.8 million bbl, with 6.7 per cent primary recovery. However, net pay data from the M pool shows that the current pool boundaries do not accurately represent the absolute pool limits. Extent of the pool is defined by a diagenetically controlled permeability pinchout, where reduced permeability allows water migration, while simultaneously retarding oil migration. Total potential of the M pool has yet to be reached. Two development targets have been identified adjacent to the current M pool boundaries based on reservoir facies thickness, net pay, and production data. Development of these areas would expand the pool boundaries by 632 ha, increasing M pool total OOIP to 28.5 million bbl, leaving an undeveloped 18.7 million bbl.

  6. Effect of regional climate warming on the phenology of butterflies in boreal forests in Manitoba, Canada.

    Science.gov (United States)

    Westwood, A R; Blair, D

    2010-08-01

    We examined the effect of regional climate warming on the phenology of butterfly species in boreal forest ecosystems in Manitoba, Canada. For the period 1971-2004, the mean monthly temperatures in January, September, and December increased significantly, as did the mean temperatures for several concurrent monthly periods. The mean annual temperature increased ≈ 0.05°C/yr over the study period. The annual number of frost-free days and degree-day accumulations increased as well. We measured the response of 19 common butterfly species to these temperature changes with the date of first appearance, week of peak abundance, and the length of flight period over the 33-yr period of 1972-2004. Although adult butterfly response was variable for spring and summer months, 13 of 19 species showed a significant (P butterfly species significantly affected by the warming trend. The early autumn and winter months warmed significantly, and butterflies seem to be responding to this warming trend with a change in the length of certain life stages. Two species, Junonia coenia and Euphydryas phaeton, increased their northerly ranges by ≈ 150 and 70 km, respectively. Warmer autumns and winters may be providing opportunities for range extensions of more southerly butterfly species held at bay by past climatic conditions.

  7. Trends in abundance of collared lemmings near Cape Churchill, Manitoba, Canada

    Science.gov (United States)

    Reiter, M.E.; Andersen, D.E.

    2008-01-01

    Regular, multiannual cycles observed in the population abundance of small mammals in many arctic and subarctic ecosystems have stimulated substantial research, particularly among population ecologists. Hypotheses of mechanisms generating regular cycles include predator-prey interactions, limitation of food resources, and migration or dispersal, as well as abiotic factors such as cyclic climatic variation and environmental stochasticity. In 2004 and 2005, we used indirect methods to estimate trends in population size of Richardson's collared lemmings (Dicrostonyx richardsoni) retrospectively, and evaluated the extent of synchrony between lemming populations at 2 coastal tundra study areas separated by approximately 60 km near Cape Churchill, Manitoba, Canada. We collected scars on willow plants (Salix) resulting from lemming feeding. Ages of scars ranged from 0 to 13 years at both study areas. Scar-age frequency appeared cyclic and we used nonlinear Poisson regression to model the observed scar-age frequency. Lemming populations cycled with 2.8-year periodicity and the phase of the cycle was synchronous between the 2 study areas. We suggest that our approach could be applied in multiple settings and may provide the most efficient way to gather data on small mammals across both space and time in a diversity of landscapes. ?? 2008 American Society of Mammalogists.

  8. The Manitoba Youth Justice Program: Empowering and Supporting FASD Affected Youth in Conflict with the Law.

    Science.gov (United States)

    Longstaffe, Sally Elizabeth; Chudley, Albert; Harvie, Mary Kate; Brown, Teresa; Neault, Dan; Markesteyn, Trevor John

    2017-10-04

    Fetal Alcohol Spectrum Disorder (FASD) describes a constellation of physical, cognitive, neurologic and behavioral impairments resulting from prenatal exposure to alcohol. FASD is recognized as being one of the largest causes of preventable brain injury in children. There had long been concerns that some youth in conflict with the law may be affected with FASD given repetitive patterns of offending and apparent lack of understanding of consequences of their actions. In 2004 funding was received from Justice Canada for a pilot project with a cross departmental steering committee working together to determine a best way of working across systems to provide FASD assessments to these youth. It was recognized that provision of timely FASD assessments would allow the Court to provide more meaningful sentences taking into account the youth's strengths and challenges and enhance the chances of decreased recidivism and increase chances of rehabilitation. This paper describes the basic science around FASD and its' diagnosis, provides a history of the Manitoba FASD Youth Justice Program and reports on legal issues, structure, statistics, accomplishments and ongoing future challenges.

  9. Performance of administrative case definitions for comorbidity in multiple sclerosis in Manitoba and Nova Scotia.

    Science.gov (United States)

    Marrie, R A; Fisk, J D; Stadnyk, K J; Tremlett, H; Wolfson, C; Warren, S; Bhan, V; Yu, B N

    2014-07-01

    As the population ages and the prevalence of comorbid conditions increases, the need for feasible, validated methods of comorbidity surveillance in chronic diseases such as multiple sclerosis (MS) increases. Using kappa (k) statistics, we evaluated the performance of administrative case definitions for comorbidities commonly observed in MS by comparing agreement between Manitoba (MB) administrative data and self-report (n = 606) and Nova Scotia (NS) administrative data and self-report (n = 1923). Agreement between the administrative definitions and self-report was substantial for hypertension (k = 0.69 [NS], 0.76 [MB]) and diabetes (k = 0.70 [NS], 0.66 [MB]); moderate for hyperlipidemia (k = 0.53 [NS], 0.51 [MB]) and heart disease (k = 0.42 [NS], 0.51 [MB]) and fair for anxiety (k = 0.27 [NS], 0.26 [MB]). In NS, agreement was substantial for inflammatory bowel disease (k = 0.71) and moderate for epilepsy (k = 0.48). Administrative definitions for commonly observed comorbidities in MS performed well in 2 distinct jurisdictions. This suggests that they could be used more broadly across Canada and in national studies.

  10. Species diversity and phylogeographical affinities of the Branchiopoda (Crustacea) of Churchill, Manitoba, Canada.

    Science.gov (United States)

    Jeffery, Nicholas W; Elías-Gutiérrez, Manuel; Adamowicz, Sarah J

    2011-01-01

    The region of Churchill, Manitoba, contains a wide variety of habitats representative of both the boreal forest and arctic tundra and has been used as a model site for biodiversity studies for nearly seven decades within Canada. Much previous work has been done in Churchill to study the Daphnia pulex species complex in particular, but no study has completed a wide-scale survey on the crustacean species that inhabit Churchill's aquatic ecosystems using molecular markers. We have employed DNA barcoding to study the diversity of the Branchiopoda (Crustacea) in a wide variety of freshwater habitats and to determine the likely origins of the Churchill fauna following the last glaciation. The standard animal barcode marker (COI) was sequenced for 327 specimens, and a 3% divergence threshold was used to delineate potential species. We found 42 provisional and valid branchiopod species from this survey alone, including several cryptic lineages, in comparison with the 25 previously recorded from previous ecological works. Using published sequence data, we explored the phylogeographic affinities of Churchill's branchiopods, finding that the Churchill fauna apparently originated from all directions from multiple glacial refugia (including southern, Beringian, and high arctic regions). Overall, these microcrustaceans are very diverse in Churchill and contain multiple species complexes. The present study introduces among the first sequences for some understudied genera, for which further work is required to delineate species boundaries and develop a more complete understanding of branchiopod diversity over a larger spatial scale.

  11. DNA barcoding facilitates associations and diagnoses for Trichoptera larvae of the Churchill (Manitoba, Canada) area.

    Science.gov (United States)

    Ruiter, David E; Boyle, Elizabeth E; Zhou, Xin

    2013-02-20

    The North American Trichoptera larvae are poorly known at the species level, despite their importance in the understanding of freshwater fauna and critical use in biomonitoring. This study focused on morphological diagnoses for larvae occurring in the Churchill, Manitoba area, representing the largest larval association effort for the caddisflies at any given locality thus far. The current DNA barcode reference library of Trichoptera (available on the Barcode of Life Data Systems) was utilized to provide larval-adult associations. The present study collected an additional 23 new species records for the Churchill area, increasing the total Trichoptera richness to 91 species. We were able to associate 62 larval taxa, comprising 68.1% of the Churchill area Trichoptera taxa. This endeavor to identify immature life stage for the caddisflies enabled the development of morphological diagnoses, production of photographs and an appropriate taxonomic key to facilitate larval species analyses in the area. The use of DNA for associations of unknown larvae with known adults proved rapid and successful. This method should accelerate the state-of-knowledge for North American Trichoptera larvae as well as other taxonomic lineages. The morphological analysis should be useful for determination of material from the Churchill area.

  12. Microhabitat characteristics of Lapland Longspur, Calcarius lapponicus, nests at Cape Churchill, Manitoba

    Science.gov (United States)

    Boal, C.W.; Andersen, D.E.

    2005-01-01

    We examined microsite characteristics at 21 Lapland Longspur (Calcarius lapponicus) nests and land cover types in which they occurred in Wapusk National Park, Cape Churchill, Manitoba. Nests were located in four of six physiographic-vegetation land-cover types. Regardless of land-cover type, all but one nest was built on a pressure ridge or mound. Nests were built midway between the bottom and top of ridges or mounds with steeper slopes than was randomly available. Longspur nests had a distinctive southwest orientation (P < 0.001). Longspurs selected nest sites that consisted of comparatively greater amounts of shrub species and lesser amounts of moss than were randomly available. Nests were generally well concealed by vegetation (mean = 67.0%) and concealment was negatively associated with amount of graminoid species at the nest (P = 0.0005). Our nesting habitat data may facilitate a better understanding of breeding Lapland Longspur habitat requirements, and potential impacts of habitat degradation by increasing Snow Goose (Chen caerulescens) populations in the study area.

  13. Species Diversity and Phylogeographical Affinities of the Branchiopoda (Crustacea) of Churchill, Manitoba, Canada

    Science.gov (United States)

    Jeffery, Nicholas W.; Elías-Gutiérrez, Manuel; Adamowicz, Sarah J.

    2011-01-01

    The region of Churchill, Manitoba, contains a wide variety of habitats representative of both the boreal forest and arctic tundra and has been used as a model site for biodiversity studies for nearly seven decades within Canada. Much previous work has been done in Churchill to study the Daphnia pulex species complex in particular, but no study has completed a wide-scale survey on the crustacean species that inhabit Churchill's aquatic ecosystems using molecular markers. We have employed DNA barcoding to study the diversity of the Branchiopoda (Crustacea) in a wide variety of freshwater habitats and to determine the likely origins of the Churchill fauna following the last glaciation. The standard animal barcode marker (COI) was sequenced for 327 specimens, and a 3% divergence threshold was used to delineate potential species. We found 42 provisional and valid branchiopod species from this survey alone, including several cryptic lineages, in comparison with the 25 previously recorded from previous ecological works. Using published sequence data, we explored the phylogeographic affinities of Churchill's branchiopods, finding that the Churchill fauna apparently originated from all directions from multiple glacial refugia (including southern, Beringian, and high arctic regions). Overall, these microcrustaceans are very diverse in Churchill and contain multiple species complexes. The present study introduces among the first sequences for some understudied genera, for which further work is required to delineate species boundaries and develop a more complete understanding of branchiopod diversity over a larger spatial scale. PMID:21610864

  14. The demography of feral alfalfa (Medicago sativa L.) populations occurring in roadside habitats in Southern Manitoba, Canada: implications for novel trait confinement.

    Science.gov (United States)

    Bagavathiannan, Muthukumar V; Gulden, Robert H; Begg, Graham S; Van Acker, Rene C

    2010-09-01

    Feral populations of cultivated crops can act as reservoirs for novel genetically engineered (GE) traits and aid in trait movement at the landscape level. However, little information is available on the potential of cultivated crops to become feral. In this study, we investigated the ferality of alfalfa populations (non-GE version) occurring in roadside habitats. Knowledge on the nature of roadside alfalfa populations would be useful for designing efficient trait confinement protocols and coexistence strategies in alfalfa. We investigated roadside alfalfa populations from 2006 to 2009 in three rural municipalities (Hanover, MacDonald, and Springfield) in Southern Manitoba, Canada. We studied the demography of these populations including seedbank, seedling recruitment, and fecundity and examined the impact of road verge mowing on key life stages of these populations. We also compared the growth and reproductive attributes of roadside and cultivated alfalfa populations. Alfalfa is reproductively successful in roadside habitats and capable of establishing self-perpetuating populations. A substantial portion of the alfalfa seeds we extracted from seedbank samples were viable but not germinable, suggesting some degree of seedbank persistence in roadside habitats. In the roadside habitat, alfalfa seedlings recruited successfully, however, seedling mortality was high when seedlings were in close proximity to well-established alfalfa plants. Mowing dramatically reduced the reproductive success of roadside alfalfa. Generally, the growth and reproduction of roadside alfalfa was comparable to cultivated alfalfa except for total fecundity. Considering the long lifespan (>10 years) of alfalfa and the levels of fecundity, seedbank, and seedling survival we observed, long-term persistence of roadside alfalfa populations seems reasonable. In the context of novel trait confinement, our results suggest that feral alfalfa populations required to be managed if there is a desire

  15. Does First Nations ancestry modify the association between gestational diabetes and subsequent diabetes: a historical prospective cohort study among women in Manitoba, Canada.

    Science.gov (United States)

    Shen, G X; Shafer, L A; Martens, P J; Sellers, E; Torshizi, A A; Ludwig, S; Phillips-Beck, W; Heaman, M; Prior, H J; McGavock, J; Morris, M; Dart, A B; Campbell, R; Dean, H J

    2016-09-01

    Over the past 30 years, the prevalence of diabetes has steadily increased among Canadians, and is particularly evident among First Nations (FN) women. The interplay between FN ancestry, gestational diabetes and the development of subsequent diabetes among mothers remains unclear. After excluding known pre-existing diabetes, we explored whether FN ancestry may modify the association between gestational diabetes and post-partum diabetes among women in Manitoba (1981-2011) via a historical prospective cohort database study. We analysed administrative data in the Population Health Research Data Repository using Kaplan-Meier survival analysis and Cox proportional hazards regression. Gestational diabetes was diagnosed in 11 906 of 404 736 deliveries (2.9%), 6.7% of FN and 2.2% of non-FN pregnant women (P women than among non-FN women (P women with gestational diabetes within the follow-up period. The hazard ratio of gestational diabetes for post-partum diabetes was 10.6 among non-FN women and 5.4 among FN women. Other factors associated with a higher risk of diabetes included lower family income among FN and non-FN women and rural/remote residences among FN women. Among non-FN women, urban residence was associated with a higher risk of diabetes. Gestational diabetes increases post-partum diabetes in FN and non-FN women. FN women had substantially more gestational diabetes or post-partum diabetes than non-FN women, partially due to socio-economic and environmental barriers. Reductions in gestational diabetes and socio-economic inequalities are required to prevent diabetes in women, particularly in FN population. © 2015 Diabetes UK.

  16. Neighborhood Socioeconomic Characteristics, Birth Outcomes and Infant Mortality among First Nations and Non-First Nations in Manitoba, Canada

    Science.gov (United States)

    Luo, Zhong-Cheng; Wilkins, Russell; Heaman, Maureen; Martens, Patricia; Smylie, Janet; Hart, Lyna; Wassimi, Spogmai; Simonet, Fabienne; Wu, Yuquan; Fraser, William D.

    2011-01-01

    Objective Little is known about the possible impacts of neighborhood socioeconomic status on birth outcomes and infant mortality among Aboriginal populations. We assessed birth outcomes and infant mortality by neighborhood socioeconomic status among First Nations and non-First Nations in Manitoba. Study Design We conducted a retrospective birth cohort study of all live births (26,176 First Nations, 129,623 non-First Nations) to Manitoba residents, 1991–2000. Maternal residential postal codes were used to assign four measures of neighborhood socioeconomic status (concerning income, education, unemployment, and lone parenthood) obtained from 1996 census data. Results First Nations women were much more likely to live in neighborhoods of low socioeconomic status. First Nations infants were much more likely to die during their first year of life [risk ratio (RR) =1.9] especially during the postneonatal period (RR=3.6). For both First Nations and non-First Nations, living in neighborhoods of low socioeconomic status was associated with an increased risk of infant death, especially postneonatal death. For non-First Nations, higher rates of pre-term and small-for-gestational-age birth were consistently observed in low socioeconomic status neighborhoods, but for First Nations the associations were less consistent across the four measures of socioeconomic status. Adjusting for neighborhood socioeconomic status, the disparities in infant and postneonatal mortality between First Nations and non-First Nations were attenuated. Conclusion Low neighborhood socioeconomic status was associated with an elevated risk of infant death even among First Nations, and may partly account for their higher rates of infant mortality compared to non-First Nations in Manitoba. PMID:22287997

  17. Recently surveyed lakes in northern Manitoba and Saskatchewan, Canada: characteristics and critical loads of acidity

    Directory of Open Access Journals (Sweden)

    Isaac WONG

    2010-08-01

    Full Text Available Based on minimal information, lakes in the western Canadian provinces of Manitoba (MB and Saskatchewan (SK have long been considered unaffected by acid rain. However, emissions of acidifying pollutants from MB smelters and oil sand processing in Alberta (AB may pose a developing threat. Surveys of 347 lakes located on geologically sensitive terrain in northern MB and SK were conducted to assess their acidification sensitivity and status. The survey domain (~193,000 km2 contained 81,494 lakes ≥1 ha in area. Small lakes dominated the inventory in terms of numbers, and large lakes dominated in terms of area. Survey lakes were selected using a stratified-random sampling design in 10 sampling blocks within the overall survey domain. Few lakes had pH <6, and only three (all in SK were acidic, i.e., Gran Alkalinity (Alk <0 μeq L–1. A broad range in lake sensitivity was apparent, and very sensitive lakes (low specific conductance, base cations and Alk were present in all sampling blocks. Dissolved organic carbon (DOC was an important constituent of many lakes. Critical loads (CL of acidity calculated using the Steady-State Water Chemistry model (SSWC revealed extremely low 5th percentile values for every block (range 1.9 to 52.7 eq ha–1 y–1. Block CL exceedances calculated using estimated S and N deposition for 2002 ranged from 54.5 to 909 eq ha–1 y–1. The largest exceedances were for sampling blocks located near smelter sources or downwind of the oil sands. Lake chemistry revealed by our surveys was compared to others conducted both nearby and outside Canada.

  18. Maternal depression and anxiety disorders (MDAD and child development: A Manitoba population-based study.

    Directory of Open Access Journals (Sweden)

    Brenda Comaskey

    Full Text Available To examine the association between maternal depression and anxiety disorders (MDAD and child development assessed during the kindergarten year.Administrative data from several health and social databases in Manitoba, Canada, were used to study 18,331 mother-child pairs. MDAD over the period from one year prior to the child's birth to the kindergarten year was defined using physician diagnoses and filled prescriptions. Child development was assessed during the kindergarten year using the Early Development Instrument (EDI which measures vulnerability across five domains of development. Structural equation modeling was used to examine associations between timing, recurrence and severity of MDAD and child outcomes. Health at Birth (preterm, low birth weight, neonatal intensive care stay and long birth hospitalization, Family Context (teen mother, lone parent, socio-economic status (SES, child age and child sex were covariates.MDAD had a modest negative association with child EDI scores across all models tested, particularly for social, emotional and physical development. Prenatal MDAD had a stronger negative association with outcomes than other time periods; however, recurrent MDAD had a stronger negative association with outcomes than any specific time period or MDAD severity. The influence of MDAD was mediated by Family Context, which had a strong, negative association with outcomes, particularly language and cognitive development.The number of time periods a child was exposed to MDAD in early childhood was more negatively associated with five areas of child development than timing or severity. Prenatal exposure may be more sensitive to MDAD than other time periods. The familial context (teen mother, lone parenthood and low SES had a stronger influence on child outcomes than MDAD. Findings can be used to inform interventions which address maternal mental health from the prenatal period onward, and to support disadvantaged families to encourage

  19. Identification of the vascular plants of Churchill, Manitoba, using a DNA barcode library

    Directory of Open Access Journals (Sweden)

    Kuzmina Maria L

    2012-11-01

    Full Text Available Abstract Background Because arctic plant communities are highly vulnerable to climate change, shifts in their composition require rapid, accurate identifications, often for specimens that lack diagnostic floral characters. The present study examines the role that DNA barcoding can play in aiding floristic evaluations in the arctic by testing the effectiveness of the core plant barcode regions (rbcL, matK and a supplemental ribosomal DNA (ITS2 marker for a well-studied flora near Churchill, Manitoba. Results This investigation examined 900 specimens representing 312 of the 354 species of vascular plants known from Churchill. Sequencing success was high for rbcL: 95% for fresh specimens and 85% for herbarium samples (mean age 20 years. ITS2 worked equally well for the fresh and herbarium material (89% and 88%. However, sequencing success was lower for matK, despite two rounds of PCR amplification, which reflected less effective primer binding and sensitivity to the DNA degradation (76% of fresh, 45% of herbaria samples. A species was considered as taxonomically resolved if its members showed at least one diagnostic difference from any other taxon in the study and formed a monophyletic clade. The highest species resolution (69% was obtained by combining information from all three genes. The joint sequence information for rbcL and matK distinguished 54% of 286 species, while rbcL and ITS2 distinguished 63% of 285 species. Discrimination of species within Salix, which constituted 8% of the flora, was particularly problematic. Despite incomplete resolution, the barcode results revealed 22 misidentified herbarium specimens, and enabled the identification of field specimens which were otherwise too immature to identify. Although seven cases of ITS2 paralogy were noted in the families Cyperaceae, Juncaceae and Juncaginaceae, this intergenic spacer played an important role in resolving congeneric plant species at Churchill. Conclusions Our results

  20. High screen time is associated with asthma in overweight Manitoba youth.

    Science.gov (United States)

    Protudjer, Jennifer; Kozyrskyj, Anita L; McGavock, Jonathan M; Ramsey, Clare D; Becker, Allan B

    2012-11-01

    Low physical activity and high sedentary behavior are associated with adverse health outcomes, including asthma. The purposes were to (1) determine if low physical activity and/or high screen time increase the risk of asthma and airway hyperresponsiveness (AHR) in youth and (2) determine if weight status modifies these associations. This is a prospective cohort study of healthy weight and overweight Canadian youth. In 2003-2005, 723 youth (8.6 ± 0.5 years; 34.0% asthma, 55.9% boys) were recruited from the 1995 Manitoba Prospective Cohort Study. In 2008-2010, 489 returned for follow-up measures (30.9% asthma, 56.6% boys). The primary exposure variables were parent-reported physical activity and screen time at 8-10 years of age. The primary outcome measures were pediatric allergist-defined asthma and AHR defined as the provocative concentration of methacholine required to induce a 20% fall in forced expiratory volume in 1 second (FEV(1)). Low physical activity (≤2 times weekly) was not associated with asthma or AHR. However, high screen time (≥1 hour/day) was associated with a greater odds of asthma at baseline (odds ratio (OR) = 2.01, 95% confidence interval (CI) = 1.20-3.37, p low screen time. This association was more pronounced among overweight youth (baseline: OR = 3.95, 95% CI = 1.70-9.12, p youth. Screen time, in addition to physical activity, should be included in clinical assessments of youth with asthma.

  1. Examining the relationship between communities' 'age-friendliness' and life satisfaction and self-perceived health in rural Manitoba, Canada.

    Science.gov (United States)

    Menec, Verena H; Nowicki, Scott

    2014-01-01

    Population aging is a worldwide phenomenon. As a response, the World Health Organization (WHO) introduced the concept of 'age-friendliness' in 2006. Age-friendliness is defined in terms of a range of domains, such as housing, opportunities for participation, and transportation. Communities that accommodate the needs of older adults in these domains will, it is thought, promote healthy, active aging. The purpose of the present study was to examine communities' age-friendliness and its relationship to health-related outcomes in a rural context. The study included 29 communities located in Manitoba, a mid-Western Canadian province, that are part of the Province of Manitoba's Age-Friendly Manitoba Initiative. As part of a needs assessment process in these communities, 593 individuals, including seniors and younger adults, completed an Age-Friendly Survey. The survey was designed to measure a variety of features in seven domains (the physical environment, housing options, the social environment, opportunities for participation, community supports and healthcare services, transportation options, and communication and information), as well as containing measures of life satisfaction and self-perceived health. Community characteristics were derived from census data. Moreover, communities were categorized on a rural-urban continuum. Multi-level regressions indicated that an overall Age-Friendly Index was positively related to both life satisfaction (b=0.019, page-friendly domains, all but housing was positively related to life satisfaction. Results were not as consistent for self-perceived health, with significant relationships emerging only for the physical environment, social environment, opportunities for participation, and transportation options. A subsequent analysis for seniors versus younger participants, respectively, indicated that significant relationships between age-friendly domains and life satisfaction and self-perceived health were restricted primarily to

  2. Barriers to population-focused health promotion: the experience of public health nurses in the province of Manitoba.

    Science.gov (United States)

    Cohen, Benita

    2006-09-01

    There is growing evidence that population health is influenced by broad socio-environmental factors that require population-focused health promotion strategies. The author reports on a study of the perspectives of public health nurses (PHNs) on the nature of their health promotion practice in the Canadian province of Manitoba, highlighting their perceptions about barriers to population-focused health promotion. A descriptive, exploratory research design was used to conduct standardized open-ended interviews with 24 PHNs in 3 geographically and demographically diverse health authorities. There were remarkable similarities in PHNs' perceptions about their practice. Three categories of barrier to population-focused health promotion were identified: barriers at the level of individual PHNs; organizational barriers (culture, policies, processes); and extra-organizational barriers at the level of the community or province. The results point to a gap between the theory that population-focused health promotion is at the heart of PHN practice and the experience of PHNs at the 3 sites. A concerted effort to address the barriers is needed so that PHNs in Manitoba can play a leadership role in creating a health-care system that truly invests in population health.

  3. Traditional and cultural approaches to childrearing: preventing early childhood caries in Norway House Cree Nation, Manitoba.

    Science.gov (United States)

    Cidro, Jaime; Zahayko, Lynelle; Lawrence, Herenia; McGregor, Margaret; McKay, Kristen

    2014-01-01

    Infant health and development is linked to a wide range of interventions including maternal nutrition and infant feeding. Early childhood caries (ECC) is a chronic condition that affects large proportions of Aboriginal children worldwide. The health of a child's mouth is linked to their overall health and wellbeing and can have a significant impact in their day-to-day experiences of eating, playing, and sleeping. The rates of ECC have increased dramatically and communities, parents, and governments are increasingly burdened with the social, economic, and personal costs associated with treatment. There is a close association between ECC and unhealthy infant feeding practices and poor oral health care for infants. This research looked at traditional and culturally based approaches to healthy infant feeding and oral health care for infants in one remote First Nations community in northern Manitoba, Canada. Research was already under way in the community in a longer term intervention-based project called the Baby Teeth Talk Study (BTT). In discussions on the interim findings of the study, participants discussed traditional cultural approaches practised in the community for healthy infant feeding and oral health. Using a participatory research approach, the authors engaged in a partnership with the community partner who assisted with the development of research questions as well as identifying research participants. Grandmothers in the community were recruited to participate in a total of 20 interviews and four focus groups. This article explores three key findings pertaining specifically to culturally based childrearing practices and infant oral health. Respondents discussed the importance of feeding infants country food (such as fish, moose and rabbit) at a young age for the overall health of the infant. Related to this was the use of traditional medicine to address oral health issues such as teething and thrush with salves made from tree bark rubbed on the gums of

  4. A descriptive qualitative examination of knowledge translation practice among health researchers in Manitoba, Canada.

    Science.gov (United States)

    Sibley, Kathryn M; Roche, Patricia L; Bell, Courtney P; Temple, Beverley; Wittmeier, Kristy D M

    2017-09-06

    The importance of effective translation of health research findings into action has been well recognized, but there is evidence to suggest that the practice of knowledge translation (KT) among health researchers is still evolving. Compared to research user stakeholders, researchers (knowledge producers) have been under-studied in this context. The goals of this study were to understand the experiences of health researchers in practicing KT in Manitoba, Canada, and identify their support needs to sustain and increase their participation in KT. Qualitative semi-structured interviews were conducted with 26 researchers studying in biomedical; clinical; health systems and services; and social, cultural, environmental and population health research. Interview questions were open-ended and probed participants' understanding of KT, their experiences in practicing KT, barriers and facilitators to practicing KT, and their needs for KT practice support. KT was broadly conceptualized across participants. Participants described a range of KT practice experiences, most of which related to dissemination. Participants also expressed a number of negative emotions associated with the practice of KT. Many individual, logistical, and systemic or organizational barriers to practicing KT were identified, which included a lack of institutional support for KT in both academic and non-academic systems. Participants described the presence of good relationships with stakeholders as a critical facilitator for practicing KT. The most commonly identified needs for supporting KT practice were access to education and training, and access to resources to increase awareness and promotion of KT. While there were few major variations in response trends across most areas of health research, the responses of biomedical researchers suggested a unique KT context, reflected by distinct conceptualizations of KT (such as commercialization as a core component), experiences (including frustration and lack of

  5. Comparing Health Status, Health Trajectories and Use of Health and Social Services between Children with and without Developmental Disabilities: A Population-Based Longitudinal Study in Manitoba

    Science.gov (United States)

    Shooshtari, Shahin; Brownell, Marni; Mills, Rosemary S. L.; Dik, Natalia; Yu, Dickie C. T.; Chateau, Dan; Burchill, Charles A.; Wetzel, Monika

    2017-01-01

    Background: Little information exists on health of children with developmental disabilities (DDs) in the Canadian province of Manitoba. Method: The present authors linked 12 years of administrative data and compared health status, changes in health and access to health and social services between children with (n = 1877) and without (n = 5661) DDs…

  6. Manitoba Physical Education Assessment 1993. French Immersion Program: Grades 4, 8, 11. Final Report = Evaluation de L'Education Physique (1993).

    Science.gov (United States)

    Manitoba Dept. of Education and Training, Winnipeg.

    This study assessed the strengths, weaknesses, and degree of implementation of the Manitoba (Canada) Physical Education curriculum in grades 4, 8, and 11 in French Immersion Schools. This report presents the conclusions and recommendations resulting from a review and interpretation of the findings by the Physical Education Educators on the grade…

  7. Manitoba Task Force on Francophone Schools Governance. Report = Groupe de travail manitobain sur la gestion des ecoles franco-manitobaines. Le rapport.

    Science.gov (United States)

    Manitoba Dept. of Education and Training, Winnipeg.

    Findings of a task force on introduction of a school governance system for Manitoba's (Canada) francophone minority population are reported. The document outlines the background--i.e., the Canadian context--of this report, principles and procedures, the resulting recommended structure for governance, and suggestions for addressing such issues as…

  8. Birth Outcomes and Infant Mortality by the Degree of Rural Isolation among First Nations and Non-First Nations in Manitoba, Canada

    Science.gov (United States)

    Luo, Zhong-Cheng; Wilkins, Russell; Heaman, Maureen; Martens, Patricia; Smylie, Janet; Hart, Lyna; Simonet, Fabienne; Wassimi, Spogmai; Wu, Yuquan; Fraser, William D.

    2010-01-01

    Context: It is unknown whether rural isolation may affect birth outcomes and infant mortality differentially for Indigenous versus non-Indigenous populations. We assessed birth outcomes and infant mortality by the degree of rural isolation among First Nations (North American Indians) and non-First Nations populations in Manitoba, Canada, a setting…

  9. Framing truths

    OpenAIRE

    Kuester, Martin

    1992-01-01

    Framing truths : parodic structures in contemporary English-Canadian historical novels. - Toronto u.a. : Univ. of Toronto Pr., 1992. - VIII, 192 S. - Zugl.: Winnipeg, Univ. of Manitoba, Diss., 1990. - (Theory/culture ; 12)

  10. Survival Analysis

    CERN Document Server

    Miller, Rupert G

    2011-01-01

    A concise summary of the statistical methods used in the analysis of survival data with censoring. Emphasizes recently developed nonparametric techniques. Outlines methods in detail and illustrates them with actual data. Discusses the theory behind each method. Includes numerous worked problems and numerical exercises.

  11. Modelling survival

    DEFF Research Database (Denmark)

    Ashauer, Roman; Albert, Carlo; Augustine, Starrlight

    2016-01-01

    well GUTS, calibrated with short-term survival data of Gammarus pulex exposed to four pesticides, can forecast effects of longer-term pulsed exposures. Thirdly, we tested the ability of GUTS to estimate 14-day median effect concentrations of malathion for a range of species and use these estimates...

  12. Lessons learned from a Canadian province-wide age-friendly initiative: the Age-Friendly Manitoba Initiative.

    Science.gov (United States)

    Menec, Verena H; Novek, Sheila; Veselyuk, Dawn; McArthur, Jennifer

    2014-01-01

    The Age-Friendly Manitoba Initiative was launched in 2008. A formative evaluation we conducted in 2011 with 44 participating rural and urban communities demonstrates considerable progress, with virtually all communities having formed an Age-Friendly Committee and conducting a community assessment to identify priorities for action. The majority of communities implemented one or more age-friendly projects. Major barriers to becoming age-friendly identified by participants included lack of funding; lack of capacity, particularly in small communities; and lack of leadership or direction. The study highlights the importance of strong leadership at all levels of government (municipal, provincial, federal); the need to support communities, particularly rural ones, as they try to become more age-friendly; and the importance of ongoing promotion of age-friendliness locally and more broadly (e.g., provincially).

  13. A comparison of the energy use and carbon release from two Manitoba farms with contrasting tillage systems

    Energy Technology Data Exchange (ETDEWEB)

    Gulden, R.H.; Entz, M.H.

    1997-07-01

    Different cropping systems were studied to determine which would result in lower energy use and carbon emissions released by manufactured inputs. A conventional tillage farming operation was compared with a zero tillage farming operation with similar crop rotations. The research was conducted at two 650 ha commercial farms in Manitoba. Data was collected for a period of 8 years. The crop rotations included combinations of canola, alfalfa, wheat, peas and barley. Results of the study show that a simple method of decreasing the energy use and carbon emissions in the conventional tillage farming system is to shift to a minimum tillage system. Even greater energy savings could be had by switching to a zero tillage system. In the case of zero tillage farming, further cost reductions might be achieved by planting more annual legume crops, or by extending the duration of the alfalfa stand in the rotation, thus cutting down on the amount of nitrogen fertilizer required. 10 refs., 1 tab.

  14. Anthropometric indices of First Nations children and youth on first entry to Manitoba/Saskatchewan residential schools—1919 to 1953

    Directory of Open Access Journals (Sweden)

    F.J. Paul Hackett

    2016-06-01

    Full Text Available Background: First Nations people are experiencing increasing rates of obesity and type 2 diabetes but no anthropometric information exists from before the 1950s to provide context to these epidemics. Objective: To compare anthropometric indices of First Nations children and youth on first entering residential schools with historical and contemporary reference groups. Methods: This observational cross-sectional study used archival records from the Department of Indian Affairs to calculate body mass index (BMI, height for age (HA and weight for age (WA of all known children and youth undergoing physical examinations on first entering residential schools in Saskatchewan and Manitoba from 1919 to 1953. Proportions of children and youth in each BMI category were determined by age, sex, time period and residential school. Z-scores for HA and WA were determined by age group and sex. Finally, median heights and weights were compared with a non-Indigenous cohort from the 1953 Canadian survey. Results: On admission to residential schools, 1,767 First Nations children and youth (847 boys, 920 girls were more likely to have normal BMIs (79.8% than Canadian children and youth today (66.5%, but lower rates of overweight/obesity (10.9% vs. 32.0% and higher rates of underweight (9.3% vs. −2, age-specific median heights tended to be higher than Canadian children and youth in 1953. Under 3% of children and youth had WA Z-scores of >−2. Conclusions: A large majority of First Nations children and youth exhibited normal anthropometric indices on first entering residential schools in Manitoba and Saskatchewan from 1919 to 1953. These historical findings provide an important context to the current epidemics of obesity and type 2 diabetes and suggest that the nutritional conditions in these First Nations children's communities were satisfactory during the residential school era.

  15. Population Genomics of Lake Sturgeon (Acipenser fulvescens) in the Churchill, Hayes, and Nelson Rivers. A draft report prepared for Manitoba Hydro by Université Laval and North/South Consultants Inc.

    OpenAIRE

    Gosselin, Thierry; Nelson, Patrick A.; McDougall, Craig A.; Bernatchez, Louis

    2015-01-01

    A report prepared for Manitoba Hydro by Université Laval and North/South Consultants Inc. Manitoba Hydro has been investigating the feasibility of developing a hydroelectric generating station at the Conawapa site, located approximately 29 km downstream of the Limestone Generating Station (GS) on the Nelson River. An Environmental Studies Program was developed to provide information that will: - assist in applying the principles of sustainable development in designing and planning the...

  16. Perceived Barriers to SME-College Collaboration: The Case of the Province of Manitoba

    Science.gov (United States)

    Edmunds, T. Keith

    2017-01-01

    Since their creation, community colleges have had a mandate to be responsive to their communities, often through relationships with local business. As globalization and technological advancements increase pressure on small businesses (SMEs), the role of colleges in helping these SMEs to innovate in order to survive becomes clearer. Relationships…

  17. Special Education in Manitoba. Policy and Procedural Guidelines for the Education of Students with Special Needs in the Public School System = Education de 'l'enfance en difficulte au Manitoba. Lignes directrices concernant les eleves qui ovt des besions speciaux et qui frequentent les ecoles publiques.

    Science.gov (United States)

    Manitoba Dept. of Education and Training, Winnipeg.

    The document, presented in both English and French, brings together the policies and general guidelines which direct the provision of special education programs and services in Manitoba. Guidelines are intended to assist school districts in implementing: (1) an education programming and placement process for students who require modification of…

  18. Landscape-scale distribution and persistence of genetically modified oilseed rape (Brassica napus) in Manitoba, Canada.

    Science.gov (United States)

    Knispel, Alexis L; McLachlan, Stéphane M

    2010-01-01

    Genetically modified herbicide-tolerant (GMHT) oilseed rape (OSR; Brassica napus L.) was approved for commercial cultivation in Canada in 1995 and currently represents over 95% of the OSR grown in western Canada. After a decade of widespread cultivation, GMHT volunteers represent an increasing management problem in cultivated fields and are ubiquitous in adjacent ruderal habitats, where they contribute to the spread of transgenes. However, few studies have considered escaped GMHT OSR populations in North America, and even fewer have been conducted at large spatial scales (i.e. landscape scales). In particular, the contribution of landscape structure and large-scale anthropogenic dispersal processes to the persistence and spread of escaped GMHT OSR remains poorly understood. We conducted a multi-year survey of the landscape-scale distribution of escaped OSR plants adjacent to roads and cultivated fields. Our objective was to examine the long-term dynamics of escaped OSR at large spatial scales and to assess the relative importance of landscape and localised factors to the persistence and spread of these plants outside of cultivation. From 2005 to 2007, we surveyed escaped OSR plants along roadsides and field edges at 12 locations in three agricultural landscapes in southern Manitoba where GMHT OSR is widely grown. Data were analysed to examine temporal changes at large spatial scales and to determine factors affecting the distribution of escaped OSR plants in roadside and field edge habitats within agricultural landscapes. Additionally, we assessed the potential for seed dispersal between escaped populations by comparing the relative spatial distribution of roadside and field edge OSR. Densities of escaped OSR fluctuated over space and time in both roadside and field edge habitats, though the proportion of GMHT plants was high (93-100%). Escaped OSR was positively affected by agricultural landscape (indicative of cropping intensity) and by the presence of an

  19. Opportunities and Barriers to Rural, Remote and First Nation Health Services Research in Canada: Comparing Access to Administrative Claims Data in Manitoba and British Columbia

    OpenAIRE

    Lavoie, Jos?e G.; Wong, Sabrina; Katz, Alan; Sinclair, Stephanie

    2016-01-01

    Access to geographically disaggregated data is essential for the pursuit of meaningful rural, remote and First Nation health services research. This paper explores the opportunities and challenges associated with undertaking administrative claims data research in the context of two different models of administrative data management: the Manitoba and British Columbia models. We argue that two conditions must be in place to support rural, remote and First Nation health services research: (1) pa...

  20. Manitoba mothers and fetal alcohol spectrum disorders study (MBMomsFASD): protocol for a population-based cohort study using linked administrative data

    Science.gov (United States)

    Singal, Deepa; Brownell, Marni; Hanlon-Dearman, Ana; Chateau, Dan; Longstaffe, Sally; Roos, Leslie L

    2016-01-01

    Introduction Fetal alcohol spectrum disorder (FASD) is a significant public health concern. To prevent FASD, factors that place women at risk for giving birth to children with FASD must be investigated; however, there are little data in this area. This paper describes the development of the Manitoba mothers and FASD study, a retrospective cohort of mothers whose children were diagnosed with FASD, generated to investigate: (1) risk factors associated with giving birth to children with FASD; (2) maternal physical and health outcomes, as well as the usage of health and social services. Methods The study population will be identified by linking children diagnosed with FASD from a provincially centralised FASD assessment clinic (from 31 March 1999 to 31 March 2012) to their birth mothers using de-identified administrative health data housed at the Manitoba Centre for Health Policy. Preliminary analysis has identified over 700 mothers, which is the largest sample size in this field to date. A comparison cohort of women with children who did not have an FASD diagnosis matched on the region of residence, date of birth of child with FASD and socioeconomic status will be generated to compare exposures and outcomes. Potential demographic, socioeconomic, family history, and physical and mental health risk factors will be investigated by linking a range of health and social databases, furthering insight into the root causes of drinking during pregnancy. The longitudinal data will allow us to document the usage patterns of healthcare and social services throughout significant periods in these women's lives to identify opportunities for prevention. Ethics and dissemination Ethical approval has been obtained by the University of Manitoba's Health Research Ethics Board and the Manitoba Health Information Privacy Committee. Dissemination of study results will include engagement of stakeholders and policymakers through presentations and reports for policymakers, in parallel with

  1. Innovations’ Survival

    Directory of Open Access Journals (Sweden)

    Jakub Tabas

    2016-01-01

    Full Text Available Innovations currently represent a tool of maintaining the going concern of a business entity and its competitiveness. However, effects of innovations are not infinite and if an innovation should constantly preserve a life of business entity, it has to be a continual chain of innovations, i.e. continual process. Effective live of a single innovation is limited while the limitation is derived especially from industry. The paper provides the results of research on innovations effects in the financial performance of small and medium-sized enterprises in the Czech Republic. Objective of this paper is to determine the length and intensity of the effects of technical innovations in company’s financial performance. The economic effect of innovations has been measured at application of company’s gross production power while the Deviation Analysis has been applied for three years’ time series. Subsequently the Survival Analysis has been applied. The analyses are elaborated for three statistical samples of SMEs constructed in accordance to the industry. The results obtained show significant differences in innovations’ survival within these three samples of enterprises then. The results are quite specific for the industries, and are confronted and discussed with the results of authors’ former research on the issue.

  2. Participant outcomes, perceptions, and experiences in the Internationally Educated Engineers Qualification Program, University of Manitoba: An exploratory study

    Science.gov (United States)

    Friesen, Marcia R.

    Immigration, economic, and regulatory trends in Canada have challenged all professions to examine the processes by which immigrant professionals (international graduates) achieve professional licensure and meaningful employment in Canada. The Internationally Educated Engineers Qualification Program (IEEQ) at the University of Manitoba was developed as an alternate pathway to integrate international engineering graduates into the engineering profession in Manitoba. However, universities have the neither mandate nor the historical practice to facilitate licensure for immigrant professionals and, thus, the knowledge base for program development and delivery is predominantly experiential. This study was developed to address the void in the knowledge base and support the program's ongoing development by conducting a critical, exploratory, participant-oriented evaluation of the IEEQ Program for both formative and summative purposes. The research questions focussed on how the IEEQ participants perceived and described their experiences in the IEEQ Program, and how the participants' outcomes in the IEEQ Program compared to international engineering graduates pursuing other licensing pathways. The study was built on an interpretivist theoretical approach that supported a primarily qualitative methodology with selected quantitative elements. Data collection was grounded in focus group interviews, written questionnaires, student reports, and program records for data collection, with inductive data analysis for qualitative data and descriptive statistics for quantitative data. The findings yielded rich understandings of participants' experiences in the IEEQ Program, their outcomes relative to international engineering graduates (IEGs) pursuing other licensing pathways, and their perceptions of their own adaptation to the Canadian engineering profession. Specifically, the study suggests that foreign credentials recognition processes have tended to focus on the recognition and

  3. Trends in Ostracoda and Cladocera distribution and water chemistry in subarctic Canada: Churchill (Manitoba lakes and ponds revisited

    Directory of Open Access Journals (Sweden)

    Finn A. Viehberg

    2017-03-01

    Full Text Available Ponds and lakes distributed across northern treeline in the Hudson Bay Lowlands near Churchill (Manitoba were revisited to analyse and document the local ecoclimatic and limnological changes that occurred over the period 1997-2012. Our analyses revealed that single events may cause significant changes in salinity, pH and silicate content because of the limited buffer capacity of the inter-connected waters. Planktic freshwater microcrustaceans (Cladocera presented less diverse assemblages and appeared to favour waters that are situated in the boreal forest, while the diversity of benthic species assemblages (Cladocera and Ostracoda was highest in waters located closer to the coastline and in open tundra vegetation. We identified three species that are distinctive for the boreal ecozone (i.e., Candona acuta, Can. acutula and Can. decora and two species (i.e., Tonnacypris glacialis and Can. rawsoni that are elements of (sub-arctic landscapes and potentially endangered as the northern treeline expands due to rapid warming. These species are thought to be useful indicators for future ecosystem quality assessments and/or ecosystem service management programs. Our findings were compared to other studies completed in the boreal Yukon Territory and revealed that species diversity is closely linked to landscape history.

  4. Six-year prevalence and incidence of diabetic retinopathy and cost-effectiveness of tele-ophthalmology in Manitoba.

    Science.gov (United States)

    Kanjee, Raageen; Dookeran, Ravi I; Mathen, Mathen K; Stockl, Frank A; Leicht, Richard

    2017-11-01

    The purpose of this study was to evaluate the diabetic retinopathy (DR) tele-ophthalmology screening program in Manitoba to determine prevalence and incidence of DR, as well as to estimate the program's cost-effectiveness. Retrospective chart review. A total of 4676 patients with type 2 diabetes examined 9334 times from 2007 to 2013. Focused ophthalmic histories were recorded and examinations were performed by trained nurses, including visual acuities, intraocular pressure, and mydriatic 7 standard field stereoscopic fundus photography. Images were evaluated by retinal specialists according to the Early Treatment of Diabetic Retinopathy Study criteria. DR prevalence and incidence were then calculated during the study period. Cost-effectiveness was estimated by comparing the cost of running the tele-ophthalmology program compared with the cost of screening the same volume of patients in-office. The average prevalence of any DR in each year was 25.1%. The cumulative incidence of DR across 6 years was 17.1% (95% CI, 15.4%-18.7%). The average savings per tele-ophthalmology examination was $1007. DR is highly prevalent among the studied population. Tele-ophthalmology provides a cost-effective means of monitoring patients as well as identifying new or treatable disease. Copyright © 2017. Published by Elsevier Inc.

  5. Soil-Air Mercury Flux near a Large Industrial Emission Source before and after Closure (Flin Flon, Manitoba, Canada).

    Science.gov (United States)

    Eckley, Chris S; Blanchard, Pierrette; McLennan, Daniel; Mintz, Rachel; Sekela, Mark

    2015-08-18

    Prior to its closure, the base-metal smelter in Flin Flon, Manitoba, Canada was one of the North America's largest mercury (Hg) emission sources. Our project objective was to understand the exchange of Hg between the soil and the air before and after the smelter closure. Field and laboratory Hg flux measurements were conducted to identify the controlling variables and used for spatial and temporal scaling. Study results showed that deposition from the smelter resulted in the surrounding soil being enriched in Hg (up to 99 μg g(-1)) as well as other metals. During the period of smelter operation, air concentrations were elevated (30 ± 19 ng m(-3)), and the soil was a net Hg sink (daily flux: -3.8 ng m(-2) h(-1)). Following the smelter closure, air Hg(0) concentrations were reduced, and the soils had large emissions (daily flux: 108 ng m(-2) h(-1)). The annual scaling of soil Hg emissions following the smelter closure indicated that the landscape impacted by smelter deposition emitted or re-emitted almost 100 kg per year. Elevated soil Hg concentrations and emissions are predicted to continue for hundreds of years before background concentrations are re-established. Overall, the results indicate that legacy Hg deposition will continue to cycle in the environment long after point-source reductions.

  6. Lesion Distribution and Epidemiology of Mycobacterium bovis in Elk and White-Tailed Deer in South-Western Manitoba, Canada

    Directory of Open Access Journals (Sweden)

    Todd K. Shury

    2011-01-01

    Full Text Available Surveillance for Mycobacterium bovis in free-ranging elk (Cervus elaphus and white-tailed deer (Odocoileus virginianus from south-western Manitoba was carried out from 1997 to 2010 to describe the lesions, epidemiology, and geographic distribution of disease. Tissues were cultured from animals killed by hunters, culled for management, blood-tested, or found opportunistically. Period prevalence in elk was approximately six times higher than deer, suggesting a significant reservoir role for elk, but that infected deer may also be involved. Prevalence was consistently higher in elk compared to deer in a small core area and prevalence declines since 2003 are likely due to a combination of management factors instituted during that time. Older age classes and animals sampled from the core area were at significantly higher risk of being culture positive. Positive elk and deer were more likely to be found through blood testing, opportunistic surveillance, and culling compared to hunting. No non-lesioned, culture-positive elk were detected in this study compared to previous studies in red deer.

  7. Change in Trabecular Bone Score (TBS) With Antiresorptive Therapy Does Not Predict Fracture in Women: The Manitoba BMD Cohort.

    Science.gov (United States)

    Leslie, William D; Majumdar, Sumit R; Morin, Suzanne N; Hans, Didier; Lix, Lisa M

    2017-03-01

    Bone mineral density (BMD) and trabecular bone score (TBS), along with additional clinical risk factors, can be used to identify individuals at high fracture risk. Whether change in TBS in untreated or treated women independently affects fracture risk is unclear. Using the Manitoba (Canada) DXA Registry containing all BMD results for the population we identified 9044 women age ≥40 years with two consecutive DXA scans and who were not receiving osteoporosis treatment at baseline (baseline mean age 62 ± 10 years). We examined BMD and TBS change, osteoporosis treatment, and incident major osteoporotic fractures (MOFs) for each individual. Over a mean of 7.7 years follow-up, 770 women developed an incident MOF. During the interval between the two DXA scans (mean, 4.1 years), 5083 women initiated osteoporosis treatment (bisphosphonate use 80%) whereas 3961 women did not receive any osteoporosis treatment. Larger gains in both BMD and TBS were seen in women with greater adherence to osteoporosis medication (p for trend fracture decrease 20%; 95% CI, 13% to 26%; p fractures in women who initiated osteoporosis treatment (p = 0.10). Among untreated women neither change in BMD or TBS predicted fractures. We conclude that, unlike antiresorptive treatment-related changes in BMD, change in lumbar spine TBS is not a useful indicator of fracture risk irrespective of osteoporosis treatment. © 2016 American Society for Bone and Mineral Research. © 2016 American Society for Bone and Mineral Research.

  8. Non-invasive mechanical ventilation

    African Journals Online (AJOL)

    Nicky

    2005-07-10

    Jul 10, 2005 ... University of Manitoba and Manitoba Institute of Child Health, Winnipeg, Canada. B Louise Giles, MD, FRCPC ... breathing during sleep.15-17 Patients who are at high risk of aspiration or have copious secretions, unstable cardiovascular disease or extreme anxiety may not tolerate NIV and as such should ...

  9. Using Graph Theory to Understand First Nations Connections

    Science.gov (United States)

    Peters, Jehu; Metz, Don

    2015-01-01

    Children of the Earth High School in Winnipeg, Manitoba, is a school dedicated to incorporating Aboriginal perspectives into all areas of the Manitoba curriculum and is attended by an almost exclusive Aboriginal population. Many of these students come from a First Nations community and are related to others who come from such communities, the…

  10. Prevalence and risk factors of caregiver reported Severe Early Childhood Caries in Manitoba First Nations children: results from the RHS Phase 2 (2008-2010).

    Science.gov (United States)

    Schroth, Robert J; Halchuk, Shelley; Star, Leona

    2013-01-01

    The high prevalence and severity of caries among Canadian First Nations children is a growing concern. Dental surgery in hospital is often necessary to treat the signs of decay but does not address the underlying factors contributing to its development. The purpose of this study was to determine the prevalence and risk factors of caregiver-reported Baby Bottle Tooth Decay (BBTD), or Severe Early Childhood Caries (S-ECC), among preschool children recruited in Phase 2 of the First Nations Regional Longitudinal Health Survey (RHS). Cross-sectional study including interviews with caregivers. This study was limited to data from Manitoba First Nations participating in the RHS Phase 2 (2008-10). Data were restricted to caregiver interviews for their child children responded. According to caregiver reports, 102/410 (24.9%) children had S-ECC. Further, 65.0% responded that their child had already undergone treatment for caries. Children with S-ECC were significantly older than those without. S-ECC was also associated with paternal education levels and employment status, and maternal smoking during pregnancy. Breastfed children were less likely to have S-ECC, while consuming drink crystal beverages in bottles, and daily intake of soft drinks, juice, sweets and fast food were associated with increased risk. Those who reported that healthcare services were not available and were not culturally appropriate were significantly more likely to have children with S-ECC. Caregiver reports suggest that nearly 1 in every 4 children has been affected by S-ECC. Identified risk factors for Manitoba First Nations children included age, education and employment, dietary practices, access to care, and disruption to family and culture. This local evidence can be used to help inform future caries prevention activities in these Manitoba communities.

  11. Protocol for establishing an infant feeding database linkable with population-based administrative data: a prospective cohort study in Manitoba, Canada

    Science.gov (United States)

    Nickel, Nathan Christopher; Warda, Lynne; Kummer, Leslie; Chateau, Joanne; Heaman, Maureen; Green, Chris; Katz, Alan; Paul, Julia; Perchuk, Carolyn; Girard, Darlene; Larocque, Lorraine; Enns, Jennifer Emily; Shaw, Souradet

    2017-01-01

    Introduction Breast feeding is associated with many health benefits for mothers and infants. But despite extensive public health efforts to promote breast feeding, many mothers do not achieve their own breastfeeding goals; and, inequities in breastfeeding rates persist between high and low-income mother–infant dyads. Developing targeted programme to support breastfeeding dyads and reduce inequities between mothers of different socioeconomic status are a priority for public health practitioners and health policy decision-makers; however, many jurisdictions lack the timely and comprehensive population-level data on infant-feeding practices required to monitor trends in breastfeeding initiation and duration. This protocol describes the establishment of a population-based infant-feeding database in the Canadian province of Manitoba, providing opportunities to develop and evaluate breastfeeding support programme. Methods and analysis Routinely collected administrative health data on mothers’ infant-feeding practices will be captured during regular vaccination visits using the Teleform fax tool, which converts handwritten information to an electronic format. The infant-feeding data will be linked to the Manitoba Population Research Data Repository, a comprehensive collection of population-based information spanning health, education and social services domains. The linkage will allow us to answer research questions about infant-feeding practices and to evaluate how effective current initiatives promoting breast feeding are. Ethics and dissemination Approvals have been granted by the Health Research Ethics Board at the University of Manitoba. Our integrative knowledge translation approach will involve disseminating findings through government and community briefings, presenting at academic conferences and publishing in scientific journals. PMID:29061626

  12. Protocol for establishing an infant feeding database linkable with population-based administrative data: a prospective cohort study in Manitoba, Canada.

    Science.gov (United States)

    Nickel, Nathan Christopher; Warda, Lynne; Kummer, Leslie; Chateau, Joanne; Heaman, Maureen; Green, Chris; Katz, Alan; Paul, Julia; Perchuk, Carolyn; Girard, Darlene; Larocque, Lorraine; Enns, Jennifer Emily; Shaw, Souradet

    2017-10-22

    Breast feeding is associated with many health benefits for mothers and infants. But despite extensive public health efforts to promote breast feeding, many mothers do not achieve their own breastfeeding goals; and, inequities in breastfeeding rates persist between high and low-income mother-infant dyads. Developing targeted programme to support breastfeeding dyads and reduce inequities between mothers of different socioeconomic status are a priority for public health practitioners and health policy decision-makers; however, many jurisdictions lack the timely and comprehensive population-level data on infant-feeding practices required to monitor trends in breastfeeding initiation and duration. This protocol describes the establishment of a population-based infant-feeding database in the Canadian province of Manitoba, providing opportunities to develop and evaluate breastfeeding support programme. Routinely collected administrative health data on mothers' infant-feeding practices will be captured during regular vaccination visits using the Teleform fax tool, which converts handwritten information to an electronic format. The infant-feeding data will be linked to the Manitoba Population Research Data Repository, a comprehensive collection of population-based information spanning health, education and social services domains. The linkage will allow us to answer research questions about infant-feeding practices and to evaluate how effective current initiatives promoting breast feeding are. Approvals have been granted by the Health Research Ethics Board at the University of Manitoba. Our integrative knowledge translation approach will involve disseminating findings through government and community briefings, presenting at academic conferences and publishing in scientific journals. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Report of an equity-focused health impact assessment of a proposed universal parenting program in Manitoba.

    Science.gov (United States)

    Cohen, Benita E; Ateah, Christine A; Chartier, Mariette J; Anderson DeCoteau, Marcia; Harris, Elizabeth; Serwonka, Karen

    2016-06-27

    To assess potential inequitable impacts of a proposed Teen Triple P Positive Parenting Program (Teen PPP) in Manitoba to achieve equity of access and outcomes for families of diverse backgrounds; recommend (if required) alternative actions to promote greater equity of access and outcomes for families participating in Teen PPP; and evaluate the influence of recommendations on implementation of the proposed program. An equity-focused health impact assessment (EfHIA) of the proposed Teen PPP was conducted, using a standard EfHIA framework. Methods used to assess potential Teen PPP impacts included: a literature review, key informant interviews and 14 community consultations. Evidence was analyzed, summarized and presented to the project Steering Committee (SC), along with draft recommendations for ensuring that equity is considered in Teen PPP planning and rollout. The SC prioritized 12 possible inequitable impacts of Teen PPP with potential to prevent certain parents/caregivers either from accessing the proposed program or benefitting adequately from the program, causing them to drop out prematurely. Recommendations for avoiding these impacts were finalized by the SC and presented to provincial government officials responsible for the proposed program. Follow-up interviews with these individuals indicated that the recommendations were well received and raised equity-related issues that will be considered in future program planning decisions. EfHIA is a proven planning tool for ensuring that health equity is considered in all policies, which is one of the necessary conditions for reducing inequities and closing the health equity gap throughout Canada within a generation.

  14. 25-year analysis of a dental undergraduate research training program (BSc Dent) at the University of Manitoba Faculty of Dentistry.

    Science.gov (United States)

    Scott, J E; de Vries, J; Iacopino, A M

    2008-12-01

    Research in the context of the dental school has traditionally been focused on institutional/faculty accomplishments and generating new knowledge to benefit the profession. Only recently have significant efforts been made to expand the overall research programming into the formal dental curriculum, to provide students with a baseline exposure to the research and critical thinking processes, encourage evidence-based decision-making, and stimulate interest in academic/research careers. Various approaches to curriculum reform and the establishment of multiple levels of student research opportunities are now part of the educational fabric of many dental schools worldwide. Many of the preliminary reports regarding the success and vitality of these programs have used outcomes measures and metrics that emphasize cultural changes within institutions, student research productivity, and student career preferences after graduation. However, there have not been any reports from long-standing programs (a minimum of 25 years of cumulative data) that describe dental school graduates who have had the benefit of research/training experiences during their dental education. The University of Manitoba Faculty of Dentistry initiated a BSc Dent program in 1980 that awarded a formal degree for significant research experiences taking place within the laboratories of the Faculty-based researchers and has continued to develop and expand this program. The success of the program has been demonstrated by the continued and increasing demands for entry, the academic achievements of the graduates, and the numbers of graduates who have completed advanced education/training programs or returned to the Faculty as instructors. Analysis of our long-term data validates many recent hypotheses and short-term observations regarding the benefits of dental student research programs. This information may be useful in the design and implementation of dental student research programs at other dental schools.

  15. Community Development to Feed the Family in Northern Manitoba Communities: Evaluating Food Activities based on Their Food Sovereighnty, Food Security, and Sustainable Livelihood Outcomes

    Directory of Open Access Journals (Sweden)

    Mohammad Ashraful Alam

    2012-12-01

    Full Text Available This article explores food-related activities and their impacts on sustainable livelihood assets, food sovereignty, and food security, and provides insight for future food-related community development. Analysis is based on community food assessments conducted in 14 Northern Manitoba communities and included a food security survey, price survey, and interviews. The lack of community control over development in First Nation and other Northern remote and rural communities in Northern Manitoba is found to undermine both food sovereignty and sustainable livelihoods, while creating high levels of food insecurity. According to logit models, sharing country foods increases food sovereignty and sustainable livelihoods, and has a stronger relationship to food security than either road access to retail stores in urban centres or increased competition between stores. The model predicts that rates of food insecurity for a community with a country foods program and with access to public transit and roads at 95% would be lower than the Canadian average of 92%.RÉSUMÉCet article explore les activités relatives à l’alimentation et leur impact sur les biens durables ainsi que sur la souveraineté et la sécurité alimentaires tout en ouvrant des perspectives sur le développement communautaire futur relatif à l’alimentation. L’analyse se fonde sur une recherche menée dans quatorze communautés du nord du Manitoba et comprend un premier sondage sur la sécurité alimentaire, un second sondage sur les prix, et des entrevues. Le manque de contrôle du développement dans les communautés reculées du nord du Manitoba, tant autochtones que non-autochtones, mine à la fois la souveraineté alimentaire et les moyens d’existence durables tout en provoquant de hauts niveaux d’insécurité alimentaire. Selon un modèle Logit, le partage d’aliments locaux permet une souveraineté alimentaire et une autonomie durable tout en ayant un meilleur impact sur la

  16. Tobacco use cessation services provided by dentists and dental hygienists in Manitoba: part 1. Influence of practitioner demographics and psychosocial factors.

    Science.gov (United States)

    Brothwell, Douglas J; Gelskey, Shirley C

    2008-12-01

    Despite high rates of tobacco use, overwhelming evidence of detrimental effects on oral health, smokers" desire to stop using tobacco and the availability of efficacious brief intervention counselling (BIC) strategies, the delivery of cessation services by dental practitioners is, at best, inconsistent. The purpose of this part of our study was to assess BIC practice patterns among dentists and dental hygienists in Manitoba and to determine whether demographic or psychosocial factors influence BIC delivery. A pre-piloted survey was mailed to all licensed dentists (547) and registered dental hygienists (566) in the province. In all, 514 oral health practitioners responded for a 46.2% response rate. Most oral health practitioners in Manitoba are not providing consistent BIC; however, 54.9% (279/508) of survey respondents advise smokers to quit. Women clinicians are more likely to ask, assess and assist patients and tend to advise against smoking more frequently than men; younger practitioners are more likely to ask and assess readiness to quit smoking than older practitioners; dental hygienists are more likely to provide assistance to quit than dentists. Assisting is the service least frequently provided by practitioners. The barriers to providing BIC are different for male and female practitioners and for dentists and dental hygienists; practitioners with more psychosocial barriers provide BIC less frequently than those reporting fewer barriers. Only 36.9% (188/510) of practitioners report feeling adequately prepared to assist smokers to quit.

  17. The chemical composition, antioxidant activity and α-glucosidase inhibitory activity of water-extractable polysaccharide conjugates from northern Manitoba lingonberry

    Directory of Open Access Journals (Sweden)

    Kelly A. Ross

    2015-12-01

    Full Text Available Lingonberry (Vaccinium vitis-idaea L. is a small northern fruit that has been harvested historically by native North Americans and Northern Europeans. These berries have been traditionally consumed as food and for medicinal use. Lingonberries are reported to be rich in vitamin C, benzoic acid, and anthocyanins, which have been implicated in health benefits associated with the consumption of lingonberries. We hypothesized that water-extractable polysaccharides, conjugated with proteins and/or phenolics may also serve as bioactive compounds with potential health benefits in northern Manitoba lingonberries. A hot water extraction was used to obtain water-extractable polysaccharides from lingonberries and the water-extractable polysaccharides were fractionated into water-eluted/neutral and NaCl-eluted/acidic fractions using chromatography. The water-extractable polysaccharides were evaluated for their chemical composition and structural features. The antioxidant activity (FRAP and ABTS assays and potential of the polysaccharides to serve as α-glucosidase inhibitors were determined. The chemical composition and structural features of the water-extractable polysaccharides were influenced by fraction. The water-extractable polysaccharides and fractions all possessed antioxidant activity, while only the water-extractable polysaccharide conjugates and NaCl-eluted/acidic fraction demonstrated appreciable α-glucosidase inhibition. This work provides novel information indicating that water-extractable polysaccharide conjugates isolated from northern Manitoba lingonberry demonstrate bioactivity.

  18. What is the comparative health status and associated risk factors for the Métis? A population-based study in Manitoba, Canada

    Directory of Open Access Journals (Sweden)

    Martens Patricia J

    2011-10-01

    Full Text Available Abstract Background Métis are descendants of early 17th century relationships between North American Indians and Europeans. This study's objectives were: (1 to compare the health status of the Métis people to all other residents of Manitoba, Canada; and (2 to analyze factors in predicting the likelihood of diabetes and related lower limb amputation. Methods Using de-identified administrative databases plus the Métis Population Database housed at the Manitoba Centre for Health Policy, age/sex-adjusted rates of mortality and disease were calculated for Métis (n = 73,016 and all other Manitobans (n = 1,104,672. Diseases included: hypertension, arthritis, diabetes, ischemic heart disease (age 19+; osteoporosis (age 50+; acute myocardial infarction (AMI and stroke (age 40+; total respiratory morbidity (TRM, all ages. Using logistic regression, predictors of diabetes (2004/05-2006/07 and diabetes-related lower-limb amputations (2002/03-2006/07 were analyzed. Results Disease rates were higher for Métis compared to all others: premature mortality before age 75 (4.0 vs. 3.3 per 1000, p Conclusion Despite universal healthcare, Métis' illness and mortality rates are mostly higher. Although elevated diabetes risk persists for the Métis even after adjusting for sociodemographic, healthcare and comorbidity variables, the risk of amputation for Métis appears more related to healthcare access rather than ethnicity.

  19. Adjusting Hip Fracture Probability in Men and Women Using Hip Axis Length: the Manitoba Bone Density Database.

    Science.gov (United States)

    Leslie, William D; Lix, Lisa M; Morin, Suzanne N; Johansson, Helena; Odén, Anders; McCloskey, Eugene V; Kanis, John A

    2016-01-01

    Most studies report that longer hip axis length (HAL) is associated with increased hip fracture risk in women, but comparable data in men are sparse. Using a registry of all dual-energy X-ray absorptiometry (DXA) results for Manitoba, Canada, we identified 4738 men and 50,420 women aged 40 yr and older with baseline hip DXA results, HAL measurements, and Fracture Risk Assessment Tool (FRAX) hip fracture probability computed with femoral neck bone mineral density (BMD). Population-based health service records were assessed for a subsequent hospitalization with a primary diagnosis of hip fracture. During mean 6.2 yr of follow-up, 70 men and 1020 women developed incident hip fractures. Mean HAL was significantly greater in those with vs without incident hip fractures (men 123.0 ± 7.6 vs 121.3 ± 7.4 mm, p = 0.050; women 106.9 ± 6.2 vs 104.6 ± 6.2 mm, p hip fracture risk by 3.6% in men (p = 0.022) and 4.6% in women (p hip fracture probability, each millimeter increase in HAL increased hip fracture risk by 3.4% in men (p = 0.031) and 4.8% in women (p hip fracture probability 4.7% for every millimeter that HAL is above the sex-specific average, relative decrease in hip fracture probability 3.8% for every millimeter that HAL is below the sex-specific average. We concluded that greater DXA-derived HAL is associated with increased incident hip fracture risk in both men and women, and this risk is independent of BMD and FRAX probability. Copyright © 2016 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

  20. Greenhouse gas fluxes and budget for an annual cropping system in the Red River Valley, Manitoba, Canada

    Science.gov (United States)

    Glenn, Aaron James

    Agriculture contributes significantly to national and global greenhouse gas (GHG) inventories but there is considerable control over management decisions and changes in production methods could lead to a significant reduction and possible mitigation of emissions from the sector. For example, conservation tillage practices have been suggested as a method of sequestering atmospheric carbon dioxide (CO2), however, many questions remain unanswered regarding the short-term efficacy of the production method and knowledge gaps exist regarding possible interactions with essential nutrient cycles, and the production of non-CO2 GHGs, such as nitrous oxide (N2O). Between autumn 2005 and 2009, a micrometeorological flux system was used to determine net CO2 and (N2O exchange from an annual cropping system situated on clay soil in the Red River Valley of southern Manitoba. Four plots (4-ha each) were independently evaluated and planted to corn in 2006 and faba bean in 2007; in 2008, two spring wheat plots were monitored. As well, during the non-growing season in 2006-2007 following corn harvest, a second micrometeorological flux system capable of simultaneously measuring stable C isotopologue (12CO2 and 13CO 2) fluxes was operated at the site. Tillage intensity and crop management practices were examined for their influence on GHG emissions. Significant inter-annual variability in CO2 and (N2O fluxes as a function of crop and related management activities was observed. Tillage intensity did not affect GHG emissions from the site. After accounting for harvest removals, the net ecosystem C budgets were 510 (source), 3140 (source) and -480 (sink) kg C/ha/year for the three respective crop years, summing to a three-year loss of 3170 kg C/ha. Stable C isotope flux measurements during the non-growing season following corn harvest indicated that approximately 70 % and 20 -- 30 % of the total respiration flux originated from crop residue C during the fall of 2006 and spring of 2007

  1. Prevalence and risk factors of caregiver reported Severe Early Childhood Caries in Manitoba First Nations children: results from the RHS Phase 2 (2008–2010)

    Science.gov (United States)

    Schroth, Robert J.; Halchuk, Shelley; Star, Leona

    2013-01-01

    Objectives The high prevalence and severity of caries among Canadian First Nations children is a growing concern. Dental surgery in hospital is often necessary to treat the signs of decay but does not address the underlying factors contributing to its development. The purpose of this study was to determine the prevalence and risk factors of caregiver-reported Baby Bottle Tooth Decay (BBTD), or Severe Early Childhood Caries (S-ECC), among preschool children recruited in Phase 2 of the First Nations Regional Longitudinal Health Survey (RHS). Study Design Cross-sectional study including interviews with caregivers. Methods This study was limited to data from Manitoba First Nations participating in the RHS Phase 2 (2008–10). Data were restricted to caregiver interviews for their child <72 months of age. The main variable of interest was caregiver-reported BBTD, an antecedent term for S-ECC. Data analysis included descriptive statistics and bivariate analyses; p≤0.05 was significant. Results Overall, caregivers of 431 preschool children responded. According to caregiver reports, 102/410 (24.9%) children had S-ECC. Further, 65.0% responded that their child had already undergone treatment for caries. Children with S-ECC were significantly older than those without. S-ECC was also associated with paternal education levels and employment status, and maternal smoking during pregnancy. Breastfed children were less likely to have S-ECC, while consuming drink crystal beverages in bottles, and daily intake of soft drinks, juice, sweets and fast food were associated with increased risk. Those who reported that healthcare services were not available and were not culturally appropriate were significantly more likely to have children with S-ECC. Conclusions Caregiver reports suggest that nearly 1 in every 4 children has been affected by S-ECC. Identified risk factors for Manitoba First Nations children included age, education and employment, dietary practices, access to care, and

  2. Prevalence and risk factors of caregiver reported Severe Early Childhood Caries in Manitoba First Nations children: results from the RHS Phase 2 (2008–2010

    Directory of Open Access Journals (Sweden)

    Robert J. Schroth

    2013-08-01

    Full Text Available Objectives. The high prevalence and severity of caries among Canadian First Nations children is a growing concern. Dental surgery in hospital is often necessary to treat the signs of decay but does not address the underlying factors contributing to its development. The purpose of this study was to determine the prevalence and risk factors of caregiver-reported Baby Bottle Tooth Decay (BBTD, or Severe Early Childhood Caries (S-ECC, among preschool children recruited in Phase 2 of the First Nations Regional Longitudinal Health Survey (RHS. Study Design. Cross-sectional study including interviews with caregivers. Methods. This study was limited to data from Manitoba First Nations participating in the RHS Phase 2 (2008–10. Data were restricted to caregiver interviews for their child <72 months of age. The main variable of interest was caregiver-reported BBTD, an antecedent term for S-ECC. Data analysis included descriptive statistics and bivariate analyses; p≤0.05 was significant. Results. Overall, caregivers of 431 preschool children responded. According to caregiver reports, 102/410 (24.9% children had S-ECC. Further, 65.0% responded that their child had already undergone treatment for caries. Children with S-ECC were significantly older than those without. S-ECC was also associated with paternal education levels and employment status, and maternal smoking during pregnancy. Breastfed children were less likely to have S-ECC, while consuming drink crystal beverages in bottles, and daily intake of soft drinks, juice, sweets and fast food were associated with increased risk. Those who reported that healthcare services were not available and were not culturally appropriate were significantly more likely to have children with S-ECC. Conclusions. Caregiver reports suggest that nearly 1 in every 4 children has been affected by S-ECC. Identified risk factors for Manitoba First Nations children included age, education and employment, dietary practices

  3. Assessment of an enhanced geothermal system targeting the Prairie Evaporite Formation of the Williston Basin in SW Manitoba

    Science.gov (United States)

    Holländer, Hartmut; Niloofar, Firoozy

    2017-04-01

    Canada has a large potential for geothermal energy production. High thermal resources are recognized at the volcanic belt within the Canadian Cordillera due to the difference between the oceanic and the continental heat flux which creates a border with high heat flow (as high as 150°C/km) along the volcanic belt. However, also regions with lower heat flow such as the Western Canadian Sedimentary Basin (WCSB) is of interest for geothermal usage. The Williston Basin as part of the WCSB shows low thermal gradients of 25-40°C/km. The geology and lithology of Williston Basin show the presence of halite, potassium salts and carbonate wedges within the Prairie Evaporite formation. Halite is the mineral form (salt) of sodium chloride (NaCl) which decreases thermal resistance providing paths of heat transfer to the surface and has 2-3 times higher thermal conductivity comparing to other types of minerals. The potential of a proposed enhanced geothermal system (EGS) to provide adequate energy to a 10-megawatt electricity production plant was investigated. Borehole data from the Manitoban part of the Williston Basin were collected, and two numerical models were built. One model was created for Tilston, SW Manitoba and the second at a generic site in southern Saskatchewan. Geology differs between the sites in terms of layer thicknesses and their depths. The geological sequence is identical. Both sites contain the Prairie Evaporite which consists mainly of halite. The low thermal resistance of the Prairie Evaporite is assumed to be the driving force behind a relatively high temperature at a low depth, which translates into a lower drilling cost to reach the desired layer. The Prairie Evaporite Formation is located at the Tilston site at a depth of 1.5 km with a reservoir thickness of 118 m, while the similar generic's reservoir is present at a depth of 3 km. The design suggested a two well system having one injection and one pumping well. Saline formations are impermeable and

  4. Feasibility of using coyotes (Canis latrans) as sentinels for bovine mycobacteriosis (Mycobacterium bovis) infection in wild cervids in and around Riding Mountain National Park, Manitoba, Canada.

    Science.gov (United States)

    Sangster, Cheryl; Bergeson, Doug; Lutze-Wallace, Cyril; Crichton, Vince; Wobeser, Gary

    2007-07-01

    Elk (Cervus elaphus manitobensis) and white-tailed deer (Odocoileus virginianus) in the Riding Mountain National Park (RMNP) region of southwestern Manitoba have been identified as a likely wildlife reservoir of Mycobacterium bovis, the causative agent of bovine mycobacteriosis in livestock. The feasibility of using coyotes (Canis latrans) collected from trappers as a sentinel species was investigated. Retropharyngeal, mesenteric, and colonic lymph nodes and tonsils collected at necropsy from 82 coyotes were examined by bacterial culture, polymerase chain reaction (PCR), and acid-fast histopathology. Mycobacterium bovis was not identified in any animal by culture or PCR although Mycobacterium avium species were isolated. A single acid-fast organism was identified on histopathologic examination of one animal. Based on the methods used in this study, trapper-caught coyotes do not appear to be a sensitive sentinel species of M. bovis infection in cervids in and around RMNP.

  5. Trajectories of objectively measured sedentary time among secondary students in Manitoba, Canada in the context of a province-wide physical education policy: A longitudinal analysis.

    Science.gov (United States)

    Zuo, Fei; Comte, Melisa; So, Jannice; Rosella, Laura; McGavock, Jonathan; Hobin, Erin

    2016-06-27

    Canadian adolescents' sedentary behaviour (SB) is poorly understood and greatly understudied compared to physical activity (PA). Accumulating evidence suggests that SB poses long-term health risks regardless of PA levels. To design effective interventions that target SB, it is critical to first understand adolescents' sedentary time (ST) trajectories in a Canadian context. Therefore, we examined longitudinal trajectories of Manitoba students' ST from 2008 to 2011 and identified associated factors in the context of a province-wide physical education (PE) policy. Secondary schools offering grades 9 through 12 were randomly selected in blocks to represent the urban and rural geography of Manitoba. In each selected school (n = 31), a convenience sample of grade 9 or 10 PE classes was recruited, leading to a final sample of 447 students. To assess ST, participants wore accelerometers on 7 consecutive days at baseline (2008) and during at least one follow-up period (2009, 2010 and 2011). At baseline, students accumulated an average of 540 minutes/day of ST. Over the course of secondary school, students' ST trajectories remained stable. Females compared to males had a slightly higher rate of decline in ST (p = 0.035), adjusting for socio-demographic variables. ST trajectories were not associated with baseline PA, body mass index and school neighbourhood socio-economic status. Adolescent ST remained high throughout secondary school. SB may be well established by early adolescence and track through late adolescence. Our findings suggest the potential need for additional interventions to reduce SB before and over the course of secondary school.

  6. Weather and Management Effects over Nine Years of Net Ecosystem Direct Greenhouse Gas Emissions from a Cropping System in the Red River Valley, Manitoba

    Science.gov (United States)

    Tenuta, M.; Amiro, B. D.

    2014-12-01

    Variation in weather and crop management practices strongly determines direct greenhouse gas emissions (CO2 and N2O) from agricultural crop land. Thus a long-term study was established to relate weather and management variations to direct emissions in the Northern Great Plains of Canada. Continuously emission determinations of CO2 and N2O were established at the Trace Gas Manitoba (TGAS-MAN) Long Term Greenhouse Gas Monitoring Site at Glenlea, Manitoba, using the flux gradient micrometeorlogical technique with a tunable diode laser analyzer. The soil is poorly drained clay in the Red River Valley. The field experiment consisted of four 4-hectare plots planted to corn in 2006 and faba bean in 2007. In 2008, grass-alfalfa forage was introduced to two plots (annual - perennial) and grown until 2011 whereas the other two plots (annual) were planted to annual crops: spring wheat, rapeseed, barley and spring wheat in 2008, 2009, 2010 and 2011, respectively. In late September of 2011 the grass-alfalfa forage was killed and in 2012, 2013 and 2014 all four plots were planted with corn, soybean and spring wheat, respectively. Management decisions increased emissions such as fertilizer N addition, and hay, straw and silage crop removal greatly increased emissions while choosing legume grain and perennial crops reduced emissions. Weather variation affecting seasonal and daily soil moisture, length of spring freeze-thaw period, and crop yield served to increase or decrease emissions. The variation in management and weather will be discussed in regards to impact on net emissions over the nine year study and answer if development of greenhouse gas neutral cropping systems is possible.

  7. From primary nurse to collaborative nursing care team: Early feedback on a new model.

    Science.gov (United States)

    Klaasen, Kathleen; Groenewegen, Tracy; Mitchell, Lori A; Wilson, Sandy

    2016-05-01

    This article discusses key findings from a preliminary review of a nursing care delivery model implemented in Winnipeg, Manitoba, by the Winnipeg Regional Health Authority Home Care Program in 2014. Results suggest that the model is generally seen positively by staff but challenging to implement, given established administrative practices. To meet future demands on the healthcare system, home care programs need policies and procedures that empower nurses to perform as true community health nurses. © 2016 The Canadian College of Health Leaders.

  8. Multinationals and plant survival

    DEFF Research Database (Denmark)

    Bandick, Roger

    2010-01-01

    The aim of this paper is twofold: first, to investigate how different ownership structures affect plant survival, and second, to analyze how the presence of foreign multinational enterprises (MNEs) affects domestic plants’ survival. Using a unique and detailed data set on the Swedish manufacturing...... sector, I am able to separate plants into those owned by foreign MNEs, domestic MNEs, exporting non-MNEs, and purely domestic firms. In line with previous findings, the result, when conditioned on other factors affecting survival, shows that foreign MNE plants have lower survival rates than non......-MNE plants. However, separating the non-MNEs into exporters and non-exporters, the result shows that foreign MNE plants have higher survival rates than non-exporting non-MNEs, while the survival rates of foreign MNE plants and exporting non-MNE plants do not seem to differ. Moreover, the simple non...

  9. Greenhouse Gas Emissions Increase Following the Termination of a Perennial Legume Phase of an Annual Crop Rotation within the Red River Valley, Manitoba

    Science.gov (United States)

    Hanis, K. L.; Tenuta, M.; Amiro, B. D.; Glenn, A. J.; Maas, S.; Gervais, M.

    2013-12-01

    Perennial legume forages may have the potential to increase soil carbon sequestration and decrease nitrous oxide (N2O) emissions to the atmosphere when introduced into annual cropping systems. However, little is known about what short-term effect the return to annual cropping following termination of perennial legume forage would have on carbon dioxide (CO2) and N2O emissions. Furthermore, there are few quantitative measurements about this impact on the Canadian Prairies. A long-term field experiment to continuously measure CO2 and N2O fluxes was established at the Trace Gas Manitoba (TGAS-MAN) Long Term Greenhouse Gas Monitoring Site at Glenlea, Manitoba using the flux gradient micrometeorlogical technique with a tunable diode laser analyzer. The soil is poorly drained clay in the Red River Valley. The field experiment consisted of four 4-hectare plots planted to corn in 2006 and faba bean in 2007. In 2008, grass-alfalfa forage was introduced to two plots (annual - perennial) and grown until 2011 whereas the other two plots (annual) were planted to annual crops: spring wheat, rapeseed, barley and spring wheat in 2008, 2009, 2010 and 2011, respectively. In late September of 2011 the grass-alfalfa forage was killed and in 2012 all four plots were planted with corn. Termination of the grass-alfalfa forage resulted in greater fall CO2 emissions in 2011, greater spring melt CO2 emissions and net annual N2O emissions in 2012 from the annual-perennial plots when compared to the annual plots. Over seven crop years (2006-2012), the annual - perennial system increased carbon uptake by 3.4 Mg C ha-1 and reduced N2O emissions by 3.0 Mg CO2-eq ha-1 compared to the annual system. However after accounting for harvest removals both the annual and annual-perennial systems were net carbon sources of 5.7 and 2.5 Mg C ha-1 and net GHG sources of 38 and 24 Mg CO2-eq ha-1 respectively. We are currently following the long-term impacts of inclusion of perennial forages in an annual

  10. Tree-ring-based estimates of long-term seasonal precipitation in the Souris River Region of Saskatchewan, North Dakota and Manitoba

    Science.gov (United States)

    Ryberg, Karen R.; Vecchia, Skip V.; Akyüz, F. Adnan; Lin, Wei

    2016-01-01

    Historically unprecedented flooding occurred in the Souris River Basin of Saskatchewan, North Dakota and Manitoba in 2011, during a longer term period of wet conditions in the basin. In order to develop a model of future flows, there is a need to evaluate effects of past multidecadal climate variability and/or possible climate change on precipitation. In this study, tree-ring chronologies and historical precipitation data in a four-degree buffer around the Souris River Basin were analyzed to develop regression models that can be used for predicting long-term variations of precipitation. To focus on longer term variability, 12-year moving average precipitation was modeled in five subregions (determined through cluster analysis of measures of precipitation) of the study area over three seasons (November–February, March–June and July–October). The models used multiresolution decomposition (an additive decomposition based on powers of two using a discrete wavelet transform) of tree-ring chronologies from Canada and the US and seasonal 12-year moving average precipitation based on Adjusted and Homogenized Canadian Climate Data and US Historical Climatology Network data. Results show that precipitation varies on long-term (multidecadal) time scales of 16, 32 and 64 years. Past extended pluvial and drought events, which can vary greatly with season and subregion, were highlighted by the models. Results suggest that the recent wet period may be a part of natural variability on a very long time scale.

  11. "People try and label me as someone I'm not": The social ecology of Indigenous people living with HIV, stigma, and discrimination in Manitoba, Canada.

    Science.gov (United States)

    Woodgate, Roberta L; Zurba, Melanie; Tennent, Pauline; Cochrane, Carla; Payne, Mike; Mignone, Javier

    2017-12-01

    Indigenous peoples (First Nations, Inuit, and Métis) are currently overrepresented in the HIV epidemic in Canada and are infected at a younger age than those who are not Indigenous. This article presents our findings on the stigma and discrimination (as well as related themes such as disclosure) experienced by Indigenous people who contracted HIV in their youth and live in urban and non-urban settings in Manitoba, Canada. The findings were derived from a qualitative study that sought to understand the experiences and needs of Indigenous people living with HIV (including AIDS). We situate such experiences within a social ecological framework towards developing a better structural understanding of the impacts of stigma and discrimination on the lives of Indigenous people who are HIV positive. Stigma and discrimination caused barriers for Indigenous people living with HIV through inhibiting their ease of access to supports including family, peers, community, and long- and short-term health services. Creative forms of outreach and education that are culturally appropriate and/or rooted in culture were considered to be possibly impactful ways of reducing stigma and discrimination at the community level. Learning from communities who are successfully managing stigma also showed promise for developing new programming. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Network ties and survival

    DEFF Research Database (Denmark)

    Acheampong, George; Narteh, Bedman; Rand, John

    2017-01-01

    Poultry farming has been touted as one of the major ways by which poverty can be reduced in low-income economies like Ghana. Yet, anecdotally there is a high failure rate among these poultry farms. This current study seeks to understand the relationship between network ties and survival chances...... of small commercial poultry farms (SCPFs). We utilize data from a 2-year network survey of SCPFs in rural Ghana. The survival of these poultry farms are modelled using a lagged probit model of farms that persisted from 2014 into 2015. We find that network ties are important to the survival chances...... but this probability reduces as the number of industry ties increases but moderation with dynamic capability of the firm reverses this trend. Our findings show that not all network ties aid survival and therefore small commercial poultry farmers need to be circumspect in the network ties they cultivate and develop....

  13. Aircraft Survivability: Rotorcraft Survivability. Summer 2010

    Science.gov (United States)

    2010-01-01

    protect those who serve to protect us?” The answer is a mixed bag. I am fortunate to have joined a group of dedicated men and women who represent this...and Service subject matter experts on rotorcraft safety and survivability to complete the study and report the results to the Joint Chiefs of...Operations and Support CDD TEMP DT DT/OT LUT IOT &E BLRIP TEMP TEMP LRIP Acquisition & LFT Strategies B C LFT&E Review Requirements Approve TEMPs

  14. Proof-Carrying Survivability

    Science.gov (United States)

    2013-01-15

    pp.289-302 ( Impact factor : 2.09). 2. Julic, J. and Zuo, Y. (2012). “An RFID Survivability Impact Model in the Military Domain”, Proc. of 18 th...Availability, Reliability and Security, 40(4), pp. 406-418 ( Impact factor : 2.016). 10. Zuo, Y. (2010). “A Holistic Approach for Specification of Security... Impact factor : 1.596). 20. Zuo, Y., Pimple, M. and Lande, S. (2009). “A Framework for RFID Survivability Requirement Analysis and Specification”, Proc

  15. Proposed amendment for Presidential Permit PP-63 and associated modifications to 500 kV international transmission line, Forbes, Minnesota to Manitoba, Canada Northern States Power Company. Final Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1992-02-01

    Northern States Power Company, (NSP), a Minnesota investor owned utility has applied to the Office of Fossil Energy, United States Department of Energy, to amend Presidential Permit PP-63 to allow for alterations to the 500 kV transmission line and as sedated facilities currently regulated by this permit. The alterations proposed for the 500 kV line owned by NSP are part of a long term effort sponsored by NSP to upgrade the existing NSP transmission system to allow for increased exchange of electricity with the Manitoba Hydro-Electric Board. Presidential Permit PP-63 authorized NSP to construct, connect, operate and maintain a 500 kV line at the United States/Canadian border approximately seven-and-a-half miles west of Warroad in Roseau County, Minnesota. This line connects with a 500 kV line owned and operated by the Manitoba Hydro-Electric Board (MHEB), which extends from Dorsey, Manitoba, Canada to the United States/Canadian border. NSP proposes to increase the electricity transfer capability of this transmission facility by constructing a new 80-acre substation on the existing 500 kV line in Roseau County, Minnesota, and upgrading the existing substation at Forbes, Minnesota. The proposed Roseau substation would contain two 41.5 ohm series capacitor banks. In addition, static VAR compensators are to be installed at the existing Forbes Substation. Approximately 5 acres would be added to the 30-acre Forbes site to house the additional equipment. No new lines would enter or exit the facility. NSP proposes to place the new Roseau Substation in service in May 1993 and to complete the upgrading of the Forbes Substation in March 1994. The primary, initial purpose of these modifications is to enable NSP to import 400 megawatts of electric power from MHEB during the summer months to meet peak electrical demand in the Minneapolis-St. Paul area. It is expected that this power transfer would begin in 1993.

  16. The influence of lead content in drinking water, household dust, soil, and paint on blood lead levels of children in Flin Flon, Manitoba and Creighton, Saskatchewan.

    Science.gov (United States)

    Safruk, Adam M; McGregor, Erin; Whitfield Aslund, Melissa L; Cheung, Paul H; Pinsent, Celine; Jackson, Blair J; Hair, Alan T; Lee, Murray; Sigal, Elliot A

    2017-09-01

    Lead exposure continues to be an important health issue despite the general removal of lead sources in commercial and industrial applications. Low levels of lead exposure have been found to produce adverse neurodevelopmental effects in children with no evidence that a threshold exists for this critical endpoint. Blood lead levels (BLLs) were measured in children (n=118) under the age of 7years in the northern Canadian smelter community of Flin Flon, Manitoba and Creighton, Saskatchewan. An environmental sampling component was included to examine the relationship between lead content in outdoor soil, household dust, tap water, and paint within a given household and the corresponding BLLs in participating children. The geometric mean (GM) BLL for study participants was 1.41μg/dL. Blood lead levels varied slightly by age category with the lowest levels found among the children under age 2 (GM=1.11μg/dL) and the highest levels found among children between 2 and 3years of age (GM=1.98μg/dL). Results from the multivariate modeling indicated that BLLs had a significant positive association with the age of housing (ppaint were found to be significantly correlated (ppaint, respectively). Lead concentrations in flushed (GM=0.89μg/L) and stagnant (GM=2.07μg/L and 1.18μg/L) tap water samples were not significantly correlated (p>0.05) to BLLs. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Survivability via Control Objectives

    Energy Technology Data Exchange (ETDEWEB)

    CAMPBELL,PHILIP L.

    2000-08-11

    Control objectives open an additional front in the survivability battle. A given set of control objectives is valuable if it represents good practices, it is complete (it covers all the necessary areas), and it is auditable. CobiT and BS 7799 are two examples of control objective sets.

  18. Artists’ Survival Rate

    DEFF Research Database (Denmark)

    Bille, Trine; Jensen, Søren

    2017-01-01

    The literature of cultural economics generally finds that an artistic education has no significant impact on artists’ income and careers in the arts. In our research, we have readdressed this question by looking at the artists’ survival in the arts occupations. The results show that an artistic...... education has a significant impact on artists’ careers in the arts and we find important industry differences....

  19. Education for Survival

    Science.gov (United States)

    Aldrich, Richard

    2010-01-01

    This article provides a brief overview of current approaches to education and concludes that none of these is sufficient to meet the challenges that now face the human race. It argues instead for a new concept of education for survival. (Contains 1 note.)

  20. Flexible survival regression modelling

    DEFF Research Database (Denmark)

    Cortese, Giuliana; Scheike, Thomas H; Martinussen, Torben

    2009-01-01

    Regression analysis of survival data, and more generally event history data, is typically based on Cox's regression model. We here review some recent methodology, focusing on the limitations of Cox's regression model. The key limitation is that the model is not well suited to represent time-varyi...

  1. Seeds to survive

    NARCIS (Netherlands)

    Groot, S.P.C.

    2002-01-01

    Seeds are important for man, either as propagation material of crops or directly for the production of foods, fodder and drinks. The natural function of seeds is dispersal of its genes to successive generations. Survival mechanisms seed have evolved sometimes interfere with those preferred by

  2. Survival After Retirement.

    Science.gov (United States)

    Holloway, Clark; Youngblood, Stuart A.

    1986-01-01

    Examined survival rates after retirement in a large corporation. A regression analysis was performed to control for age, sex, job status, and type of work differences that may influence longevity. Short-term suvivors seemed to undergo a different adjustment process than long-term survivors. (Author/ABL)

  3. Surviving Sepsis Campaign

    DEFF Research Database (Denmark)

    Rhodes, Andrew; Evans, Laura E; Alhazzani, Waleed

    2017-01-01

    OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012". DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings......, and to formulate recommendations as strong or weak, or best practice statement when applicable. RESULTS: The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. Overall, 32 were strong recommendations, 39 were weak recommendations...... of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality....

  4. Surviving Sepsis Campaign

    DEFF Research Database (Denmark)

    Rhodes, Andrew; Evans, Laura E; Alhazzani, Waleed

    2017-01-01

    OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings......, and to formulate recommendations as strong or weak, or best practice statement when applicable. RESULTS: The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. Overall, 32 were strong recommendations, 39 were weak recommendations...... of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality....

  5. Cracking the survival code

    Science.gov (United States)

    Füllgrabe, Jens; Heldring, Nina; Hermanson, Ola; Joseph, Bertrand

    2014-01-01

    Modifications of histones, the chief protein components of the chromatin, have emerged as critical regulators of life and death. While the “apoptotic histone code” came to light a few years ago, accumulating evidence indicates that autophagy, a cell survival pathway, is also heavily regulated by histone-modifying proteins. In this review we describe the emerging “autophagic histone code” and the role of histone modifications in the cellular life vs. death decision. PMID:24429873

  6. Artillery Survivability Model

    Science.gov (United States)

    2016-06-01

    experiment mode also enables users to set their own design of experiment by manipulating an editable CSV file. The second one is a real-time mode that...renders a 3D virtual environment of a restricted battlefield where the survivability movements of an artillery company are visualized . This mode...provides detailed visualization of the simulation and enables future experimental uses of the simulation as a training tool. 14. SUBJECT TERMS

  7. Survival analysis models and applications

    CERN Document Server

    Liu, Xian

    2012-01-01

    Survival analysis concerns sequential occurrences of events governed by probabilistic laws.  Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis.Assumes only a minimal knowledge of SAS whilst enablin

  8. Loneliness among Senior Citizens: An Empirical Report.

    Science.gov (United States)

    And Others; Perlman, Daniel

    1978-01-01

    This article reports an empirical study of loneliness among 158 senior citizens living in Winnipeg, Manitoba. Respondents each completed a self-administered questionnaire. Greater loneliness was associated with less friendship contact, fewer close friends, social anxiety, ineffectiveness in influencing others, low marital satisfaction, and low…

  9. PIC--A Self-Paced Practical Communications Program for Technical/Vocational Students.

    Science.gov (United States)

    Blicq, Ronald S.

    The Practical Industrial Communication (PIC) program is a form of individualized instruction that teaches communication skills to students in vocational/technical curricula at Red River Community College, Winnipeg, Manitoba. A placement test determines whether students begin with all or part of a ten-hour writing skills review or proceed directly…

  10. Without and within: The Implications of Employment and Ethnocultural Equity Policies for Internationally Educated Teachers

    Science.gov (United States)

    Schmidt, Clea; Block, Lee Anne

    2010-01-01

    Analyzing school division employment policies from six Winnipeg school divisions and the Manitoba K-12 Action Plan for Ethnocultural Equity (MECY, 2006), we discuss implications for the integration of internationally educated teachers in K-12 schools. Findings suggest that the policies exhibit several major limitations in advancing IET…

  11. Catholic-Schools Adolescents' Religiosity, Prosocial Values, School Attitudes, and Family Satisfaction.

    Science.gov (United States)

    Schludermann, Shirin; Schludermann, Eduard; Huynh, Cam-Loi

    This study examined the direct and indirect influences of adolescents' religiosity on selected social-emotional aspects of their development. A total of 369 boys and 372 girls attending 3 Catholic high schools in Winnipeg, Manitoba, completed a questionnaire that addressed family religion, religiosity, prosocial values, school attitudes, family…

  12. The Roles of Vitamin D, Temperature, and Viral Infections in Seasonal Risk of Acquiring Asthma/From the Authors

    National Research Council Canada - National Science Library

    William B Grant; Pingsheng Wu; William D Dupont; Marie R Griffin; Tina V Hartert

    2009-01-01

    ... with temperature (3). In addition, solar UV-B (UVB) doses were inversely correlated with risk in a latitudinally varying manner, explaining 13% of the variance in Miami, FL, 5% in Buffalo, NY, and 0.6% in Winnipeg, Manitoba. That vitamin D reduces the risk of respiratory viral infections was demonstrated in a randomized controlled trial condu...

  13. Interdependence, Disequilibrium and Growth: Reflections on the ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    John Loxley is Professor and former Head of the Department of Economics at the University of Manitoba in Winnipeg. His distinguished career includes stints at Makerere University and the University of Dares Salaam in Tanzania, as well as serving the governments of Tanzania, Uganda, Madagascar, Mozambique, and ...

  14. Mapping Nondominant Voices into Understanding Stress-Coping Mechanisms

    Science.gov (United States)

    Iwasaki, Yoshitaka; Bartlett, Judith; MacKay, Kelly; Mactavish, Jennifer; Ristock, Janice

    2008-01-01

    This study reports key findings from a research project, which examined the stress and coping mechanisms of several nondominant groups of individuals. The groups were based in Winnipeg, Manitoba, Canada and included (a) Aboriginal individuals with diabetes, (b) individuals with disabilities, and (c) gays and lesbians. Our analyses of personal…

  15. Applied survival analysis using R

    CERN Document Server

    Moore, Dirk F

    2016-01-01

    Applied Survival Analysis Using R covers the main principles of survival analysis, gives examples of how it is applied, and teaches how to put those principles to use to analyze data using R as a vehicle. Survival data, where the primary outcome is time to a specific event, arise in many areas of biomedical research, including clinical trials, epidemiological studies, and studies of animals. Many survival methods are extensions of techniques used in linear regression and categorical data, while other aspects of this field are unique to survival data. This text employs numerous actual examples to illustrate survival curve estimation, comparison of survivals of different groups, proper accounting for censoring and truncation, model variable selection, and residual analysis. Because explaining survival analysis requires more advanced mathematics than many other statistical topics, this book is organized with basic concepts and most frequently used procedures covered in earlier chapters, with more advanced topics...

  16. Survival after blood transfusion

    DEFF Research Database (Denmark)

    Kamper-Jørgensen, Mads; Ahlgren, Martin; Rostgaard, Klaus

    2008-01-01

    of transfusion recipients in Denmark and Sweden followed for up to 20 years after their first blood transfusion. Main outcome measure was all-cause mortality. RESULTS: A total of 1,118,261 transfusion recipients were identified, of whom 62.0 percent were aged 65 years or older at the time of their first...... the SMR remained significantly 1.3-fold increased. CONCLUSION: The survival and relative mortality patterns among blood transfusion recipients were characterized with unprecedented detail and precision. Our results are relevant to assessments of the consequences of possible transfusion-transmitted disease...... as well as for cost-benefit estimation of new blood safety interventions....

  17. Nuclear War Survival Skills

    Energy Technology Data Exchange (ETDEWEB)

    Kearny, C.H.

    2002-06-24

    The purpose of this book is to provide Americans with information and instructions that will significantly increase their chances of surviving a possible nuclear attack. It brings together field-tested instructions that, if followed by a large fraction of Americans during a crisis that preceded an attack, could save millions of lives. The author is convinced that the vulnerability of our country to nuclear threat or attack must be reduced and that the wide dissemination of the information contained in this book would help achieve that objective of our overall defense strategy.

  18. Design of survivable networks

    CERN Document Server

    Stoer, Mechthild

    1992-01-01

    The problem of designing a cost-efficient network that survives the failure of one or more nodes or edges of the network is critical to modern telecommunications engineering. The method developed in this book is designed to solve such problems to optimality. In particular, a cutting plane approach is described, based on polyhedral combinatorics, that is ableto solve real-world problems of this type in short computation time. These results are of interest for practitioners in the area of communication network design. The book is addressed especially to the combinatorial optimization community, but also to those who want to learn polyhedral methods. In addition, interesting new research problemsare formulated.

  19. OBESITY IN CANCER SURVIVAL

    Science.gov (United States)

    Parekh, Niyati; Chandran, Urmila; Bandera, Elisa V.

    2013-01-01

    Although obesity is a well known risk factor for several cancers, its role on cancer survival is poorly understood. We conducted a systematic literature review to assess the current evidence evaluating the impact of body adiposity on the prognosis of the three most common obesity-related cancers: prostate, colorectal, and breast. We included 33 studies of breast cancer, six studies of prostate cancer, and eight studies of colorectal cancer. We note that the evidence over-represents breast cancer survivorship research and is sparse for prostate and colorectal cancers. Overall, most studies support a relationship between body adiposity and site-specific mortality or cancer progression. However, most of the research was not specifically designed to study these outcomes and, therefore, several methodological issues should be considered before integrating their results to draw conclusions. Further research is urgently warranted to assess the long-term impact of obesity among the growing population of cancer survivors. PMID:22540252

  20. Surviving relatives after suicide

    DEFF Research Database (Denmark)

    Nørrelykke, Helle; Cohrt, Pernille

    suicide in Denmark. This means that at least 400 people undergo the trauma it is when one of their near relatives commits suicide. We also know that the loss from suicide involves a lot of conflicting feelings - like anger, shame, guilt and loss and that the lack of therapy/treatment of these difficult...... and conflicting feelings may result in pathological expansion of grief characterized by extremely reduced quality of life involving severe psychical and social consequences. Suicide a subject of taboo In the 1980s WHO drafted a health policy document (‘Health for all year 2000’) with 38 targets for attaining......We would like to focus on the surviving relatives after suicides, because it is generally accepted that it is especially difficult to recover after the loss from suicide and because we know as a fact that one suicide affects five persons on average. Every year approximately 700 people commit...

  1. Obesity in cancer survival.

    Science.gov (United States)

    Parekh, Niyati; Chandran, Urmila; Bandera, Elisa V

    2012-08-21

    Although obesity is a well-known risk factor for several cancers, its role on cancer survival is poorly understood. We conducted a systematic literature review to assess the current evidence evaluating the impact of body adiposity on the prognosis of the three most common obesity-related cancers: prostate, colorectal, and breast. We included 33 studies of breast cancer, six studies of prostate cancer, and eight studies of colo-rectal cancer. We note that the evidence overrepresents breast cancer survivorship research and is sparse for prostate and colorectal cancers. Overall, most studies support a relationship between body adiposity and site-specific mortality or cancer progression. However, most of the research was not specifically designed to study these outcomes and, therefore, several methodological issues should be considered before integrating their results to draw conclusions. Further research is urgently warranted to assess the long-term impact of obesity among the growing population of cancer survivors.

  2. Candida survival strategies.

    Science.gov (United States)

    Polke, Melanie; Hube, Bernhard; Jacobsen, Ilse D

    2015-01-01

    Only few Candida species, e.g., Candida albicans, Candida glabrata, Candida dubliniensis, and Candida parapsilosis, are successful colonizers of a human host. Under certain circumstances these species can cause infections ranging from superficial to life-threatening disseminated candidiasis. The success of C. albicans, the most prevalent and best studied Candida species, as both commensal and human pathogen depends on its genetic, biochemical, and morphological flexibility which facilitates adaptation to a wide range of host niches. In addition, formation of biofilms provides additional protection from adverse environmental conditions. Furthermore, in many host niches Candida cells coexist with members of the human microbiome. The resulting fungal-bacterial interactions have a major influence on the success of C. albicans as commensal and also influence disease development and outcome. In this chapter, we review the current knowledge of important survival strategies of Candida spp., focusing on fundamental fitness and virulence traits of C. albicans. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Psychology and survival.

    Science.gov (United States)

    Phillips, D P; Ruth, T E; Wagner, L M

    1993-11-06

    We examined the deaths of 28,169 adult Chinese-Americans, and 412,632 randomly selected, matched controls coded "white" on the death certificate. Chinese-Americans, but not whites, die significantly earlier than normal (1.3-4.9 yr) if they have a combination of disease and birthyear which Chinese astrology and medicine consider ill-fated. The more strongly a group is attached to Chinese traditions, the more years of life are lost. Our results hold for nearly all major causes of death studied. The reduction in survival cannot be completely explained by a change in the behaviour of the Chinese patient, doctor, or death-registrar, but seems to result at least partly from psychosomatic processes.

  4. Proposed Amendment to Presidential Permit PP-63 and Associated Modifications to 500-kV International Transmission Line: Forbes, Minnesota to Manitoba, Canada, Northern States Power Company. Addendum to the final Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1992-10-01

    This Addendum to the Final Environmental Assessment for the Proposed Amendment to Presidential Permit PP-63 and Associated Modifications to 500 kV International Transmission Line: Forbes, Minnesota to Manitoba, Canada (DOE/EA-587) addresses Northern States Power Company`s (NSP) proposed expansion of the Forbes Substation. The applicant has requested that the expansion take place on the west side of the substation, within the existing property line, instead of on the north side as originally proposed. All of the proposed construction would take place on property already owned by NSP. DOE has reviewed the environmental impacts associated with this minor modification and has determined that the conclusions reached in the environmental assessment and Finding of No Significant Impact prepared in connection with NSP`s original amendment request remain valid.

  5. Survival assays using Caenorhabditis elegans.

    Science.gov (United States)

    Park, Hae-Eun H; Jung, Yoonji; Lee, Seung-Jae V

    2017-02-01

    Caenorhabditis elegans is an important model organism with many useful features, including rapid development and aging, easy cultivation, and genetic tractability. Survival assays using C. elegans are powerful methods for studying physiological processes. In this review, we describe diverse types of C. elegans survival assays and discuss the aims, uses, and advantages of specific assays. C. elegans survival assays have played key roles in identifying novel genetic factors that regulate many aspects of animal physiology, such as aging and lifespan, stress response, and immunity against pathogens. Because many genetic factors discovered using C. elegans are evolutionarily conserved, survival assays can provide insights into mechanisms underlying physiological processes in mammals, including humans.

  6. Surviving a Suicide Attempt

    Directory of Open Access Journals (Sweden)

    Ahmed Al-Harrasi

    2016-09-01

    Full Text Available Suicide is a global phenomenon in all regions of the world affecting people of all age groups. It has detrimental consequences on patients, their families, and the community as a whole. There have been numerous risk factors described for suicide including mental illness, stressful life situations, loss of social support, and general despair. The association of suicide with Islam has not been extensively studied. The common impression from clinical practice is that being a practicing Muslim reduces the risk of suicide. Another factor associated with suicide is starting a patient on antidepressants. However, this has been questioned recently. This report describes a middle-aged man with depression and multiple social stressors who survived a serious suicide attempt. The discussion will focus on the factors that lead him to want to end his life and the impact of the assumed protective factors such as religious belief and family support on this act of self-harm. Such patients can be on the edge when there is an imbalance between risk factors (such as depression, insomnia, and psychosocial stressors and protective factors (like religious affiliation and family support. All physicians are advised to assess the suicide risk thoroughly in patients with depression regardless of any presumed protective factor.

  7. Surviving a Suicide Attempt.

    Science.gov (United States)

    Al-Harrasi, Ahmed; Al Maqbali, Mandhar; Al-Sinawi, Hamed

    2016-09-01

    Suicide is a global phenomenon in all regions of the world affecting people of all age groups. It has detrimental consequences on patients, their families, and the community as a whole. There have been numerous risk factors described for suicide including mental illness, stressful life situations, loss of social support, and general despair. The association of suicide with Islam has not been extensively studied. The common impression from clinical practice is that being a practicing Muslim reduces the risk of suicide. Another factor associated with suicide is starting a patient on antidepressants. However, this has been questioned recently. This report describes a middle-aged man with depression and multiple social stressors who survived a serious suicide attempt. The discussion will focus on the factors that lead him to want to end his life and the impact of the assumed protective factors such as religious belief and family support on this act of self-harm. Such patients can be on the edge when there is an imbalance between risk factors (such as depression, insomnia, and psychosocial stressors) and protective factors (like religious affiliation and family support). All physicians are advised to assess the suicide risk thoroughly in patients with depression regardless of any presumed protective factor.

  8. Will the olympics survive?.

    Science.gov (United States)

    Khosla, T.

    1977-01-01

    The United States of America dominated 58 events in athletics, field and swimming, which between them accounted for 35 per cent of all events in the Munich Olympiad. 1972; these events favour taller individuals. But, in 25 per cent of other events (1) cycling, (2) fencing, (3) gymnastics, (4) judo, (5) weightlifting and (6) Graeco Roman wrestling the U.S.A. did not win a single medal. The failure of the U.S.A. to maintain her lead in Munich was largely due to weaknesses in these other events in many of which the potential medallists can be derived from the lower half of the height distribution (events 3 to 6). These weaknesses are Russia's strength and they continued to remain unstrengthened at Montreal. Also, the domination held by the U.S.A. in swimming was seriously challenged by East Germany. The present trends indicate that the U.S.A.'s ranking is likely to slip further to the third position in Moscow 1980. Factors inhibiting the survival of the Olympics are pointed. PMID:861436

  9. Survival After Relapse of Medulloblastoma.

    Science.gov (United States)

    Koschmann, Carl; Bloom, Karina; Upadhyaya, Santhosh; Geyer, J Russell; Leary, Sarah E S

    2016-05-01

    Survival after recurrence of medulloblastoma has not been reported in an unselected cohort of patients in the contemporary era. We reviewed 55 patients diagnosed with medulloblastoma between 2000 and 2010, and treated at Seattle Children's Hospital to evaluate patterns of relapse treatment and survival. Fourteen of 47 patients (30%) over the age of 3 experienced recurrent or progressive medulloblastoma after standard therapy. The median time from diagnosis to recurrence was 18.0 months (range, 3.6 to 62.6 mo), and site of recurrence was metastatic in 86%. The median survival after relapse was 10.3 months (range, 1.3 to 80.5 mo); 3-year survival after relapse was 18%. There were trend associations between longer survival and having received additional chemotherapy (median survival 12.8 vs. 1.3 mo, P=0.16) and radiation therapy (15.4 vs. 5.9 mo, P=0.20). Isolated local relapse was significantly associated with shorter survival (1.3 vs. 12.8 mo, P=0.009). Recurrence of medulloblastoma is more likely to be metastatic than reported in previous eras. Within the limits of our small sample, our data suggest a potential survival benefit from retreatment with cytotoxic chemotherapy and radiation even in heavily pretreated patients. This report serves as a baseline against which to evaluate novel therapy combinations.

  10. Marketing child survival.

    Science.gov (United States)

    Grant, J P

    1984-01-01

    Growth monitoring charts, packets of oral rehydration salts (ORS), and vaccines, are inexpensive, life-saving, growth-protecting technologies which can enable parents to protect their children against the worst effects of poverty. Similarly, a matrix of current and easily understandable information about pregnancy, breast feeding, weaning, feeding during and immediately after illness, child spacing, and preparing and using home-made oral rehydration solutions, also could empower parents to protect the lives and the health of their children. The question arises as to how can these technologies and this information be put at the disposal of millions of families in the low-income world. The initial task of the Child Survival and Development Revolution is the communication of what is now possible, yet little is known about how to communicate information whose principal value is to the poor. There are 2 large-scale precedents: the Green Revolution, which in many instances succeeded in putting into the hands of thousands of small and large farmers the techniques and the knowledge which enabled them to double and treble the yields from their lands; and the campaign to put the knowledge and the means of family planning at the disposal of many millions of people. There are 2 lessons to be learned from these precedents: they have shown that the way to promote a people's technology and to put information at the disposal of the majority is by mobilizing all possible resources and working through all possible channels both to create the demand and to meet it; and neither the Green Revolution nor the family planning movement rally took off until they were viewed as political and economic priorities and given the full support of the nation's political leadership. Nowhere are these 2 lessons more clearly illustrated than in present-day Indonesia. Because the campaign for family planning was given high personal and political priority by the President, and because 85% of all family

  11. The virtual classroom: a summary of child health indicators.

    Science.gov (United States)

    Martens, Patricia J; Brownel, Marni D; Kozyrskyj, Anita

    2002-01-01

    To provide an overview of child health indicators and health care utilization patterns in Manitoba by comparing child health outcomes for different income groups: a) children from two different community areas of Winnipeg (Fort Garry and Point Douglas), and b) adolescents from two different parts of Manitoba (the North, and Winnipeg). Various child health indicators derived from population-based administrative data and national surveys are reported in the articles within this supplement. Childhood morbidity and mortality, health care utilization patterns, pharmaceutical use, and regional demographic information discussed in the research articles in this supplement are summarized here using comparisons of outcomes in "virtual classrooms" of 100 children. Large gradients were observed in the comparison of the virtual classrooms of 100 high school students, including the following numbers of adolescents: females on birth control pills (Winnipeg 11, North 18); injury hospitalization annually (Winnipeg 1; North 4). Gradients are observed for some child outcomes of the virtual classroom of 100, but not for others. Examples include the following numbers of children: preterm at birth (FG 7, PD 7); breastfed at birth (FG 90, PD 66); hospitalized for lower respiratory tract infection in first year (FG 3, PD 8); parents having no high school (FG 11; PD 41). Throughout Manitoba, child and adolescent health indicators and determinants of health show gradients by income as well as by geographical regions.

  12. Global Activities and Plant Survival

    DEFF Research Database (Denmark)

    Bandick, Roger

    2014-01-01

    This chapter provides an extensive review of the empirical evidence found for Sweden concerning plant survival. The result reveals that foreign MNE plants and exporting non-MNE plants have the lowest exit rates, followed by purely domestic-oriented plants, and that domestic MNE plants have...... the highest exit rates. Moreover, the exit rates of globally engaged plants seem to be unaffected by increased foreign presence, whereas there appears to be a negative impact on the survival rates of non-exporting non-MNE plants. Finally, the result reveals that the survival ratio of plants of acquired...... exporters, but not other types of plants, improves post acquisition....

  13. Cardiovascular disease incidence and survival

    DEFF Research Database (Denmark)

    Byberg, Stine; Agyemang, Charles; Zwisler, Ann Dorthe

    2016-01-01

    Studies on cardiovascular disease (CVD) incidence and survival show varying results between different ethnic groups. Our aim was to add a new dimension by exploring the role of migrant status in combination with ethnic background on incidence of-and survival from-CVD and more specifically acute...... of some types of cardiovascular disease compared to Danish-born. Family-reunified migrants on the other hand had lower rates of CVD. All migrants had better survival than Danish-born indicating that migrants may not always be disadvantaged in health....

  14. [Physical activity and cancer survival].

    Science.gov (United States)

    Romieu, Isabelle; Touillaud, Marina; Ferrari, Pietro; Bignon, Yves-Jean; Antoun, Sami; Berthouze-Aranda, Sophie; Bachmann, Patrick; Duclos, Martine; Ninot, Grégory; Romieu, Gilles; Sénesse, Pierre; Behrendt, Jan; Balosso, Jacques; Pavic, Michel; Kerbrat, Pierre; Serin, Daniel; Trédan, Olivier; Fervers, Béatrice

    2012-10-01

    Physical activity has been shown in large cohort studies to positively impact survival in cancer survivors. Existing randomized controlled trials showed a beneficial effect of physical activity on physical fitness, quality of life, anxiety and self-esteem; however, the small sample size, the short follow-up and the lack of standardization of physical activity intervention across studies impaired definite conclusion in terms of survival. Physical activity reduces adiposity and circulating estrogen levels and increases insulin sensitivity among other effects. A workshop was conducted at the International Agency for Research on Cancer in April 2011 to discuss the role of physical activity on cancer survival and the methodology to develop multicentre randomized intervention trials, including the type of physical activity to implement and its association with nutritional recommendations. The authors discuss the beneficial effect of physical activity on cancer survival with a main focus on breast cancer and report the conclusions from this workshop.

  15. Operational slack and venture survival

    OpenAIRE

    Azadegan, Arash; Patel, Pankaj; Parida, Vinit

    2013-01-01

    Slack can act as a double-edged sword. While it can buffer against environmental threats to help ensure business continuity, slack canalso be costly and reduce profitability. In this study, we focus on operational slack, the form related to the firm’s production processes. We investigate the role of operational slack on firm survival during its venture stage, when its survival is significantly challenged by environmental threats. Specifically, we explore how change in three types of environme...

  16. Monitoring survivability and infectivity of porcine epidemic diarrhea virus (PEDv in the infected on-farm earthen manure storages (EMS

    Directory of Open Access Journals (Sweden)

    Hein Min Tun

    2016-03-01

    Full Text Available In recent years, porcine epidemic diarrhea virus (PEDv has caused major epidemics, which has been a burden to North America's swine industry. Low infectious dose and high viability in the environment are major challenges in eradicating this virus. To further understand the survivability and infectivity of PEDv in the infected manure, we performed longitudinal monitoring in two open earthen manure storages (EMSs; previously referred to as lagoon from two different infected swine farms identified in the province of Manitoba, Canada. Our study revealed that PEDv could survive up to nine months in the infected EMS after the initial outbreak in the farm. The viral load varied among different layers of the EMS with an average of 1.1 × 105 copies/ml of EMS, independent of EMS temperature and pH. In both studied EMSs, the evidence of viral replication was observed through increased viral load in the later weeks of the samplings while there was no new influx of infected manure into the EMSs, which was suggestive of presence of potential alternative hosts for PEDv within the EMSs. Decreasing infectivity of virus over time irrespective of increased viral load suggested the possibility of PEDv evolution within the EMS and perhaps in the new host that negatively impacted virus infectivity. Viral load in the top layer of the EMS was low and mostly non-infective suggesting that environmental factors, such as UV and sunlight, could diminish the replicability and infectivity of the virus. Thus, frequent agitation of the EMS that could expose virus to UV and sunlight might be a potential strategy for reduction of PEDv load and infectivity in the infected EMSs.

  17. Survival Processing Eliminates Collaborative Inhibition.

    Science.gov (United States)

    Reysen, Matthew B; Bliss, Heather; Baker, Melissa A

    2017-04-11

    The present experiments examined the effect of processing words for their survival value, relevance to moving, and pleasantness on participants' free recall scores in both nominal groups (non-redundant pooled individual scores) and collaborative dyads. Overall, participants recalled more words in the survival processing conditions than in the moving and pleasantness processing conditions. Furthermore, nominal groups in both the pleasantness condition (Experiment 1) and the moving and pleasantness conditions (Experiment 2) recalled more words than collaborative groups, thereby replicating the oft-observed effect of collaborative inhibition. However, processing words for their survival value appeared to eliminate the deleterious effects of collaborative remembering in both Experiments 1 and 2. These results are discussed in the context of the retrieval strategy disruption hypothesis and the effects of both expertise and collaborative skill on group remembering.

  18. Survival in Women with NSCLC

    Science.gov (United States)

    Katcoff, Hannah; Wenzlaff, Angela S.; Schwartz, Ann G.

    2014-01-01

    Introduction Although lung cancer is the leading cause of cancer death in women, few studies have investigated the hormonal influence on survival after a lung cancer diagnosis and results have been inconsistent. We evaluated the role of reproductive and hormonal factors in predicting overall survival in women with non–small-cell lung cancer (NSCLC). Methods Population-based lung cancer cases diagnosed between November 1, 2001 and October 31, 2005 were identified through the Metropolitan Detroit Surveillance, Epidemiology, and End Results Registry. Interview and follow-up data were collected for 485 women. Cox proportional hazard regression models were used to determine hazard ratios (HRs) for death after an NSCLC diagnosis associated with reproductive and hormonal variables. Results Use of hormone therapy (HT) was associated with improved survival (HR, 0.69; 95% confidence interval, 0.54–0.89), adjusting for stage, surgery, radiation, education level, pack-years of smoking, age at diagnosis, race, and a multiplicative interaction between stage and radiation. No other reproductive or hormonal factor was associated with survival after an NSCLC diagnosis. Increased duration of HT use before the lung cancer diagnosis (132 months or longer) was associated with improved survival (HR, 0.54; 95% confidence interval, 0.37–0.78), and this finding remained significant in women taking either estrogen alone or progesterone plus estrogen, never smokers, and smokers. Conclusion These findings suggest that HT use, in particular use of estrogen plus progesterone, and long-term HT use are associated with improved survival of NSCLC. PMID:24496005

  19. Survival of Sami cancer patients

    Directory of Open Access Journals (Sweden)

    Leena Soininen

    2012-07-01

    Full Text Available Objectives. The incidence of cancer among the indigenous Sami people of Northern Finland is lower than among the Finnish general population. The survival of Sami cancer patients is not known, and therefore it is the object of this study. Study design. The cohort consisted of 2,091 Sami and 4,161 non-Sami who lived on 31 December 1978 in the two Sami municipalities of Inari and Utsjoki, which are located in Northern Finland and are 300–500 km away from the nearest central hospital. The survival experience of Sami and non-Sami cancer patients diagnosed in this cohort during 1979–2009 was compared with that of the Finnish patients outside the cohort. Methods. The Sami and non-Sami cancer patients were matched to other Finnish cancer patients for gender, age and year of diagnosis and for the site of cancer. An additional matching was done for the stage at diagnosis. Cancer-specific survival analyses were made using the Kaplan–Meier method and Cox regression modelling. Results. There were 204 Sami and 391 non-Sami cancer cases in the cohort, 20,181 matched controls without matching with stage, and 7,874 stage-matched controls. In the cancer-specific analysis without stage variable, the hazard ratio for Sami was 1.05 (95% confidence interval 0.85–1.30 and for non-Sami 1.02 (0.86–1.20, indicating no difference between the survival of those groups and other patients in Finland. Likewise, when the same was done by also matching the stage, there was no difference in cancer survival. Conclusion. Long distances to medical care or Sami ethnicity have no influence on the cancer patient survival in Northern Finland.

  20. Survival following spinal cord infarction.

    Science.gov (United States)

    New, P W; McFarlane, C L

    2013-06-01

    Retrospective open cohort. To calculate the survival of patients with spinal cord infarction and to compare the cause of death in patients with different mechanisms of ischaemic injury. Spinal Rehabilitation Unit, Melbourne, Victoria, Australia. Consecutive admissions between 1 January 1995 and 31 December 2008 with recent onset of spinal cord infarction. Linkage to the Registry of Births, Deaths and Marriages (Victoria) was used to determine survival following discharge from in-patient rehabilitation and cause of death. A total of 44 patients were admitted (males=26, 59%), with a median age of 72 years (interquartile range (IQR) 62-79). One patient died during their in-patient rehabilitation programme. In all, 14 patients (n=14/44; 33%) died during the follow-up period. The median survival after diagnosis was 56 months (IQR 28-85) and after discharge from in-patient rehabilitation was 46 months (IQR 25-74). The 1- and 5-year mortality rates were 7.0% (n=3/43; 95% confidence interval (CI)=2.4-18.6%) and 20.9% (n=9/43; 95% CI=11.4-35.2%). There was no statistically significant difference in survival between patients with the different aetiologies of spinal cord infarction (other vs idiopathic: χ(2)=0.6, P=0.7; other vs vascular: χ(2)=1.9, P=0.3). There was no relationship between survival and gender (χ(2)=0.2, P=0.6), age (χ(2)=3.0, P=0.08), level of injury (χ(2)=0.0, P=1) or American Spinal Cord Society Impairment Scale grade of spinal cord injury (χ(2)=0.02, P=0.9). Patients with spinal cord infarction appear to have a fair survival after discharge from in-patient rehabilitation, not withstanding the occurrence of risk factors of vascular disease in many patients.

  1. Genetic aspects of piglet survival

    OpenAIRE

    Knol, E.F.

    2001-01-01

    Piglet mortality is high. In the USA nearly 20% of the piglets do not survive between late gestation and weaning; 7% of the piglets die during farrowing and some 13% are lost during lactation. These statistics from the USA are no exception to the norm. Selection for increased piglet survival, if possible, could have an important economic impact.

    Litters and sows

    Data on some 33.000 litters and some 400.000 piglets from a commercial breeding progr...

  2. Frailty Models in Survival Analysis

    CERN Document Server

    Wienke, Andreas

    2010-01-01

    The concept of frailty offers a convenient way to introduce unobserved heterogeneity and associations into models for survival data. In its simplest form, frailty is an unobserved random proportionality factor that modifies the hazard function of an individual or a group of related individuals. "Frailty Models in Survival Analysis" presents a comprehensive overview of the fundamental approaches in the area of frailty models. The book extensively explores how univariate frailty models can represent unobserved heterogeneity. It also emphasizes correlated frailty models as extensions of

  3. School Leadership: Handbook for Survival.

    Science.gov (United States)

    Smith, Stuart C., Ed.; And Others

    Based on the assumption that the survival of the nation's schools and their leaders depends on these leaders having real influence over the quality of schooling, this volume draws from the work of many authorities to look at leadership from three perspectives: the person, the structure, and the skills. Chapters focusing on the person who holds the…

  4. Long-term haemodialysis survival

    DEFF Research Database (Denmark)

    Heaf, James; Nielsen, Arne Høj; Hansen, Henrik Post

    2012-01-01

    Haemodialysis (HD) treatment for end-stage renal disease bears a poor prognosis. We present a case of a patient who, apart from two transplant periods lasting 8 months in all, was treated with conventional in-centre HD three times a week and who survived for 41 years. Patients should be aware tha...

  5. Characteristics of Patients Who Survived

    NARCIS (Netherlands)

    Verlaan, Jorrit-Jan; Choi, David; Versteeg, Anne; Albert, Todd; Arts, Mark; Balabaud, Laurent; Bunger, Cody; Buchowski, Jacob Maciej; Chung, Chung Kee; Coppes, Maarten Hubert; Crockard, Hugh Alan; Depreitere, Bart; Fehlings, Michael George; Harrop, James; Kawahara, Norio; Kim, Eun Sang; Lee, Chong-Suh; Leung, Yee; Liu, Zhongjun; Martin-Benlloch, Antonio; Massicotte, Eric Maurice; Mazel, Christian; Meyer, Bernhard; Peul, Wilco; Quraishi, Nasir A.; Tokuhashi, Yasuaki; Tomita, Katsuro; Ulbricht, Christian; Wang, Michael; Oner, F. Cumhur

    2016-01-01

    Purpose Survival after metastatic cancer has improved at the cost of increased presentation with metastatic spinal disease. For patients with pathologic spinal fractures and/or spinal cord compression, surgical intervention may relieve pain and improve quality of life. Surgery is generally

  6. Genetic aspects of piglet survival

    NARCIS (Netherlands)

    Knol, E.F.

    2001-01-01

    Piglet mortality is high. In the USA nearly 20% of the piglets do not survive between late gestation and weaning; 7% of the piglets die during farrowing and some 13% are lost during lactation. These statistics from the USA are no exception to the norm. Selection for increased piglet

  7. Cool echidnas survive the fire

    Science.gov (United States)

    Nowack, Julia; Cooper, Christine Elizabeth; Geiser, Fritz

    2016-01-01

    Fires have occurred throughout history, including those associated with the meteoroid impact at the Cretaceous–Palaeogene (K–Pg) boundary that eliminated many vertebrate species. To evaluate the recent hypothesis that the survival of the K–Pg fires by ancestral mammals was dependent on their ability to use energy-conserving torpor, we studied body temperature fluctuations and activity of an egg-laying mammal, the echidna (Tachyglossus aculeatus), often considered to be a ‘living fossil’, before, during and after a prescribed burn. All but one study animal survived the fire in the prescribed burn area and echidnas remained inactive during the day(s) following the fire and substantially reduced body temperature during bouts of torpor. For weeks after the fire, all individuals remained in their original territories and compensated for changes in their habitat with a decrease in mean body temperature and activity. Our data suggest that heterothermy enables mammals to outlast the conditions during and after a fire by reducing energy expenditure, permitting periods of extended inactivity. Therefore, torpor facilitates survival in a fire-scorched landscape and consequently may have been of functional significance for mammalian survival at the K–Pg boundary. PMID:27075255

  8. Modelling survival and connectivity of

    NARCIS (Netherlands)

    van der Molen, J.; van Beek, J.; Augustine, S.; Vansteenbrugge, L.; van Walraven, L.; van Langenberg, V.; van der Veer, H.W.; Hostens, K.; Pitois, S.; Robbens, J.

    2015-01-01

    Three different models were applied to study the reproduction, survival and dispersal of Mnemiopsis leidyi in the Scheldt estuaries and the southern North Sea: a high-resolution particle tracking model with passive particles, a low-resolution particle tracking model with a reproduction model

  9. Survivability of SCADA Control Loop

    NARCIS (Netherlands)

    Camacho, José; de Boer, Pieter-Tjerk; Remke, Anne Katharina Ingrid

    2009-01-01

    The endorsement of information technologies for critical infrastructures control introduces new threats in their security and surveillance. Along with certain level of protection against attacks, it is desirable for critical processes to survive even if they succeed. A stochastic Petri Nets-based

  10. Effects of earlier sea ice breakup on survival and population size of polar bears in western Hudson Bay

    Science.gov (United States)

    Regehr, E.V.; Lunn, N.J.; Amstrup, Steven C.; Stirling, I.

    2007-01-01

    Some of the most pronounced ecological responses to climatic warming are expected to occur in polar marine regions, where temperature increases have been the greatest and sea ice provides a sensitive mechanism by which climatic conditions affect sympagic (i.e., with ice) species. Population-level effects of climatic change, however, remain difficult to quantify. We used a flexible extension of Cormack-Jolly-Seber capture-recapture models to estimate population size and survival for polar bears (Ursus maritimus), one of the most ice-dependent of Arctic marine mammals. We analyzed data for polar bears captured from 1984 to 2004 along the western coast of Hudson Bay and in the community of Churchill, Manitoba, Canada. The Western Hudson Bay polar bear population declined from 1,194 (95% CI = 1,020-1,368) in 1987 to 935 (95% CI = 794-1,076) in 2004. Total apparent survival of prime-adult polar bears (5-19 yr) was stable for females (0.93; 95% CI = 0.91-0.94) and males (0.90; 95% CI = 0.88-0.91). Survival of juvenile, subadult, and senescent-adult polar bears was correlated with spring sea ice breakup date, which was variable among years and occurred approximately 3 weeks earlier in 2004 than in 1984. We propose that this correlation provides evidence for a causal association between earlier sea ice breakup (due to climatic warming) and decreased polar bear survival. It may also explain why Churchill, like other communities along the western coast of Hudson Bay, has experienced an increase in human-polar bear interactions in recent years. Earlier sea ice breakup may have resulted in a larger number of nutritionally stressed polar bears, which are encroaching on human habitations in search of supplemental food. Because western Hudson Bay is near the southern limit of the species' range, our findings may foreshadow the demographic responses and management challenges that more northerly polar bear populations will experience if climatic warming in the Arctic continues as

  11. Individual social capital and survival

    DEFF Research Database (Denmark)

    Ejlskov, Linda; Mortensen, Rikke N; Overgaard, Charlotte

    2014-01-01

    BACKGROUND: The concept of social capital has received increasing attention as a determinant of population survival, but its significance is uncertain. We examined the importance of social capital on survival in a population study while focusing on gender differences. METHODS: We used data from...... a Danish regional health survey with a five-year follow-up period, 2007-2012 (n = 9288, 53.5% men, 46.5% women). We investigated the association between social capital and all-cause mortality, performing separate analyses on a composite measure as well as four specific dimensions of social capital while...... controlling for covariates. Analyses were performed with Cox proportional hazard models by which hazard ratios and 95% confidence intervals were calculated. RESULTS: For women, higher levels of social capital were associated with lower all-cause mortality regardless of age, socioeconomic status, health...

  12. Campylobacter virulence and survival factors.

    Science.gov (United States)

    Bolton, Declan J

    2015-06-01

    Despite over 30 years of research, campylobacteriosis is the most prevalent foodborne bacterial infection in many countries including in the European Union and the United States of America. However, relatively little is known about the virulence factors in Campylobacter or how an apparently fragile organism can survive in the food chain, often with enhanced pathogenicity. This review collates information on the virulence and survival determinants including motility, chemotaxis, adhesion, invasion, multidrug resistance, bile resistance and stress response factors. It discusses their function in transition through the food processing environment and human infection. In doing so it provides a fundamental understanding of Campylobacter, critical for improved diagnosis, surveillance and control. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Does Intelligence Provide Survival Value?

    OpenAIRE

    Cairns, John

    2009-01-01

    Intelligence is defined as a general mental capacity to reason, plan, solve problems, think abstractly, comprehend ideas, and learn. Intelligence can also be defined as the ability to acquire and apply information gathered from the environment to modify its behavior. It is this intelligence that has allowed the genus Homo to survive for 2 million years. However, recently the global financial meltdown and the deleterious effects of climate change raise the question of whether intelligence has ...

  14. Survival on Land and Sea

    Science.gov (United States)

    1943-01-01

    flower, leaf steams, and young leaves may be eaten cooked as greens provided you cook them in several changes of water to remove the bitter taste and...and become a weed almost throughout the tropics. Its bladdery pods contain a single retl tomato-like fruit that is edible. Raspberries, blackberries ...plant that 108 SURVIVAL OK LAND AND SEA is about one foot In height and has blue flowers and inflated leaf stems. The young leaves, leafy stalks

  15. Columbia Crew Survival Investigation Report

    Science.gov (United States)

    2009-01-01

    NASA commissioned the Columbia Accident Investigation Board (CAIB) to conduct a thorough review of both the technical and the organizational causes of the loss of the Space Shuttle Columbia and her crew on February 1, 2003. The accident investigation that followed determined that a large piece of insulating foam from Columbia s external tank (ET) had come off during ascent and struck the leading edge of the left wing, causing critical damage. The damage was undetected during the mission. The CAIB's findings and recommendations were published in 2003 and are available on the web at http://caib.nasa.gov/. NASA responded to the CAIB findings and recommendations with the Space Shuttle Return to Flight Implementation Plan. Significant enhancements were made to NASA's organizational structure, technical rigor, and understanding of the flight environment. The ET was redesigned to reduce foam shedding and eliminate critical debris. In 2005, NASA succeeded in returning the space shuttle to flight. In 2010, the space shuttle will complete its mission of assembling the International Space Station and will be retired to make way for the next generation of human space flight vehicles: the Constellation Program. The Space Shuttle Program recognized the importance of capturing the lessons learned from the loss of Columbia and her crew to benefit future human exploration, particularly future vehicle design. The program commissioned the Spacecraft Crew Survival Integrated Investigation Team (SCSIIT). The SCSIIT was asked to perform a comprehensive analysis of the accident, focusing on factors and events affecting crew survival, and to develop recommendations for improving crew survival for all future human space flight vehicles. To do this, the SCSIIT investigated all elements of crew survival, including the design features, equipment, training, and procedures intended to protect the crew. This report documents the SCSIIT findings, conclusions, and recommendations.

  16. Statistical analysis of survival data.

    Science.gov (United States)

    Crowley, J; Breslow, N

    1984-01-01

    A general review of the statistical techniques that the authors feel are most important in the analysis of survival data is presented. The emphasis is on the study of the duration of time between any two events as applied to people and on the nonparametric and semiparametric models most often used in these settings. The unifying concept is the hazard function, variously known as the risk, the force of mortality, or the force of transition.

  17. LATERAL SURVIVAL: AN OT ACCOUNT

    Directory of Open Access Journals (Sweden)

    Moira Yip

    2004-12-01

    Full Text Available When laterals are the targets of phonological processes, laterality may or may not survive. In a fixed feature geometry, [lateral] should be lost if its superordinate node is eliminated by either the spreading of a neighbouring node, or by coda neutralization. So if [lateral] is under Coronal (Blevins 1994, it should be lost under Place assimilation, and if [lateral] is under Sonorant Voicing (Rice & Avery 1991 it should be lost by rules that spread voicing. Yet in some languages lateral survives such spreading intact. Facts like these argue against a universal attachment of [lateral] under either Coronal or Sonorant Voicing, and in favour of an account in terms of markedness constraints on feature-co-occurrence (Padgett 2000. The core of an OT account is that IFIDENTLAT is ranked above whatever causes neutralization, such as SHARE-F or *CODAF. laterality will survive. If these rankings are reversed, we derive languages in which laterality is lost. The other significant factor is markedness. High-ranked feature co-occurrence constraints like *LATDORSAL can block spreading from affecting laterals at all.

  18. Stage at diagnosis and ovarian cancer survival

    DEFF Research Database (Denmark)

    Maringe, Camille; Walters, Sarah; Butler, John

    2012-01-01

    We investigate what role stage at diagnosis bears in international differences in ovarian cancer survival.......We investigate what role stage at diagnosis bears in international differences in ovarian cancer survival....

  19. Starvation-Survival in Haloarchaea

    Science.gov (United States)

    Winters, Yaicha D.; Lowenstein, Tim K.; Timofeeff, Michael N.

    2015-01-01

    Recent studies claiming to revive ancient microorganisms trapped in fluid inclusions in halite have warranted an investigation of long-term microbial persistence. While starvation-survival is widely reported for bacteria, it is less well known for halophilic archaea—microorganisms likely to be trapped in ancient salt crystals. To better understand microbial survival in fluid inclusions in ancient evaporites, laboratory experiments were designed to simulate growth of halophilic archaea under media-rich conditions, complete nutrient deprivation, and a controlled substrate condition (glycerol-rich) and record their responses. Haloarchaea used for this work included Hbt. salinarum and isolate DV582A-1 (genus Haloterrigena) sub-cultured from 34 kyear Death Valley salt. Hbt. salinarum and DV582A-1 reacted to nutrient limitation with morphological and population changes. Starved populations increased and most cells converted from rods to small cocci within 56 days of nutrient deprivation. The exact timing of starvation adaptations and the physical transformations differed between species, populations of the same species, and cells of the same population. This is the first study to report the timing of starvation strategies for Hbt. salinarum and DV582A-1. The morphological states in these experiments may allow differentiation between cells trapped with adequate nutrients (represented here by early stages in nutrient-rich media) from cells trapped without nutrients (represented here by experimental starvation) in ancient salt. The hypothesis that glycerol, leaked from Dunaliella, provides nutrients for the survival of haloarchaea trapped in fluid inclusions in ancient halite, is also tested. Hbt. salinarum and DV582A-1 were exposed to a mixture of lysed and intact Dunaliella for 56 days. The ability of these organisms to utilize glycerol from Dunaliella cells was assessed by documenting population growth, cell length, and cell morphology. Hbt. salinarum and DV582A-1

  20. Starvation-Survival in Haloarchaea

    Directory of Open Access Journals (Sweden)

    Yaicha D. Winters

    2015-11-01

    Full Text Available Recent studies claiming to revive ancient microorganisms trapped in fluid inclusions in halite have warranted an investigation of long-term microbial persistence. While starvation-survival is widely reported for bacteria, it is less well known for halophilic archaea—microorganisms likely to be trapped in ancient salt crystals. To better understand microbial survival in fluid inclusions in ancient evaporites, laboratory experiments were designed to simulate growth of halophilic archaea under media-rich conditions, complete nutrient deprivation, and a controlled substrate condition (glycerol-rich and record their responses. Haloarchaea used for this work included Hbt. salinarum and isolate DV582A-1 (genus Haloterrigena sub-cultured from 34 kyear Death Valley salt. Hbt. salinarum and DV582A-1 reacted to nutrient limitation with morphological and population changes. Starved populations increased and most cells converted from rods to small cocci within 56 days of nutrient deprivation. The exact timing of starvation adaptations and the physical transformations differed between species, populations of the same species, and cells of the same population. This is the first study to report the timing of starvation strategies for Hbt. salinarum and DV582A-1. The morphological states in these experiments may allow differentiation between cells trapped with adequate nutrients (represented here by early stages in nutrient-rich media from cells trapped without nutrients (represented here by experimental starvation in ancient salt. The hypothesis that glycerol, leaked from Dunaliella, provides nutrients for the survival of haloarchaea trapped in fluid inclusions in ancient halite, is also tested. Hbt. salinarum and DV582A-1 were exposed to a mixture of lysed and intact Dunaliella for 56 days. The ability of these organisms to utilize glycerol from Dunaliella cells was assessed by documenting population growth, cell length, and cell morphology. Hbt. salinarum

  1. Survival of adult martens in Northern Wisconsin

    Science.gov (United States)

    Nicholas P. McCann; Patrick A. Zollner; Jonathan H. Gilbert

    2010-01-01

    Low adult marten (Martes americana) survival may be one factor limiting their population growth >30 yr after their reintroduction in Wisconsin, USA. We estimated annual adult marten survival at 0.81 in northern Wisconsin, with lower survival during winter (0.87) than summer-fall (1.00). Fisher (Martes pennanti) and raptor kills...

  2. Long-term survival after perforated diverticulitis

    NARCIS (Netherlands)

    J. Vermeulen (Jan); M.P. Gosselink (Martijn Pieter); W.C.J. Hop (Wim); E. van der Harst (Erwin); B.E. Hansen (Bettina); G.H.H. Mannaerts (Guido); P-P. Coene (Peter Paul); W.F. Weidema (Wibo); J.F. Lange (Johan)

    2011-01-01

    textabstractAim: Short-term survival after emergency surgery for perforated diverticulitis is poor. Less is known about long-term survival. The aims of this study were to evaluate long-term survival after discharge from hospital and to identify factors associated with prognosis. Method: All patients

  3. Clustered survival data with left-truncation

    DEFF Research Database (Denmark)

    Eriksson, Frank; Martinussen, Torben; Scheike, Thomas H.

    2015-01-01

    Left-truncation occurs frequently in survival studies, and it is well known how to deal with this for univariate survival times. However, there are few results on how to estimate dependence parameters and regression effects in semiparametric models for clustered survival data with delayed entry...

  4. 46 CFR 133.105 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft. 133.105 Section 133.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.105 Survival craft. (a) Each survival craft must be approved and equipped as...

  5. 46 CFR 199.201 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft. 199.201 Section 199.201 Shipping COAST... SYSTEMS FOR CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.201 Survival craft. (a) Each survival craft must be approved and equipped as follows: (1) Each lifeboat must be...

  6. 46 CFR 199.261 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft. 199.261 Section 199.261 Shipping COAST... SYSTEMS FOR CERTAIN INSPECTED VESSELS Additional Requirements for Cargo Vessels § 199.261 Survival craft. (a) Each survival craft must be approved and equipped as follows: (1) Each lifeboat must be a totally...

  7. 46 CFR 28.120 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Survival craft. 28.120 Section 28.120 Shipping COAST... VESSELS Requirements for All Vessels § 28.120 Survival craft. (a) Except as provided in paragraphs (b) through (h) of this section and 28.305, each vessel must carry the survival craft specified in Table 28...

  8. 46 CFR 174.320 - Damage survival.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Damage survival. 174.320 Section 174.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO... survival. A hopper dredge survives assumed damage if it meets the following conditions: (a) The maximum...

  9. Surviving the crash: T-cell homeostasis

    Indian Academy of Sciences (India)

    TOSHIBA

    Spatial and temporal elements. – Cellular sites for the integration of cell death and survival cues. – Spatial regulation of Notch activity for cell survival. Page 4. Cell survival is determined by the availability and uptake of nutrients live dead. Activated T-cells. T-cells. Page 5. dead wildtype. Bax active -6A7. Nucleus – H33342.

  10. Update on rabies

    OpenAIRE

    Jackson, Alan

    2011-01-01

    Alan C JacksonDepartments of Internal Medicine (Neurology) and Medical Microbiology, University of Manitoba, Winnipeg, MB, CanadaAbstract: Human rabies is almost invariably fatal, and globally it remains an important public health problem. Our knowledge of rabies pathogenesis has been learned mainly from studies performed in experimental animal models, and a number of unresolved issues remain. In contrast with the neural pathway of spread, there is still no credible evidence that hematogenous...

  11. The dirt: industrial disease and conflict at St. Lawrence, Newfoundland

    National Research Council Canada - National Science Library

    Rennie, Rick

    2008-01-01

    ... Miners' Museum; courtesy of the Town Council of St. Lawrence, Newfoundland. Printed and bound in Canada by Hignell Book Printing Published in Canada by Fernwood Publishing Site 2A, Box 5, 32 Oceanvista Lane Black Point, Nova Scotia, B0J 1B0 and #8 - 222 Osborne St., Winnipeg, Manitoba, R3L 1Z3 www.fernwoodpublishing.ca This book has been published with ...

  12. Is ingestion of milk-associated bacteria by premature infants fed raw human milk controlled by routine bacteriologic screening?

    OpenAIRE

    Law, B J; Urias, B A; Lertzman, J; Robson, D.; Romance, L

    1989-01-01

    Expressed human milk is often used to feed premature infants. Raw milk contains bacteria which may be a source of infection. Milk banks have developed screening programs which combine periodic quantitative milk cultures with arbitrary rules specifying limits of bacterial concentration. It is unknown whether such programs succeed in preventing infants from being fed milk containing bacteria. At the Health Sciences Centre (Winnipeg, Manitoba, Canada), milk is screened once weekly. When a woman'...

  13. Systems Engineering of Unmanned DoD Systems: Following the Joint Capabilities Integration and Development System/Defense Acquisition System Process to Develop an Unmanned Ground Vehicle System

    Science.gov (United States)

    2015-12-01

    writers 2. Constraints The main constraint of the system development was using the LEGO MINDSTORMS EV3 hardware for a material solution. The...2014. Maximum LEGO ® MINDSTORMS ™ EV3 , Building robots with Java™ Brains. Winnipeg, Manitoba: Variant Press Boyd, John. 1976. “Destruction and...unmanned ground vehicle (UGV) using the LEGO MINSTORMS EV3 platform. The team named the UGV the Threat Exposure and Clearing Hardware Manipulated

  14. Survival strategies in arctic ungulates

    Directory of Open Access Journals (Sweden)

    N. J. C. Tyler

    1990-09-01

    Full Text Available Arctic ungulates usually neither freeze nor starve to death despite the rigours of winter. Physiological adaptations enable them to survive and reproduce despite long periods of intense cold and potential undernutrition. Heat conservation is achieved by excellent insulation combined with nasal heat exchange. Seasonal variation in fasting metabolic rate has been reported in several temperate and sub-arctic species of ungulates and seems to occur in muskoxen. Surprisingly, there is no evidence for this in reindeer. Both reindeer and caribou normally maintain low levels of locomotor activity in winter. Light foot loads are important for reducing energy expenditure while walking over snow. The significance and control of selective cooling of the brain during hard exercise (e.g. escape from predators is discussed. Like other cervids, reindeer and caribou display a pronounced seasonal cycle of appetite and growth which seems to have an intrinsic basis. This has two consequences. First, the animals evidently survive perfectly well despite enduring negative energy balance for long periods. Second, loss of weight in winter is not necessarily evidence of undernutrition. The main role of fat reserves, especially in males, may be to enhance reproductive success. The principal role of fat reserves in winter appears to be to provide a supplement to, rather than a substitute for, poor quality winter forage. Fat also provides an insurance against death during periods of acute starvation.

  15. Foreign Ownership and Long-term Survival

    DEFF Research Database (Denmark)

    Kronborg, Dorte; Thomsen, Steen

    2006-01-01

    Does foreign ownership enhance or decrease a firm's chances of survival? Over the 100 year period 1895-2001 this paper compares the survival of foreign subsidiaries in Denmark to a control sample matched by industry and firm size. We find that foreign-owned companies have higher survival...... probability. On average exit risk for domestic companies is 2.3 times higher than for foreign companies. First movers like Siemens, Philips, Kodak, Ford, GM or Goodyear have been active in the country for almost a century. Relative foreign survival increases with company age. However, the foreign survival...

  16. Survival paths through the forest

    DEFF Research Database (Denmark)

    Mogensen, Ulla Brasch

    when the information is high-dimensional e.g. when there are many thousands of genes or markers. In these situations machine learning methods such as the random forest can still be applied and provide reasonable prediction accuracy. The main focus in this talk is the performance of random forest...... in particular when the response is three-dimensional. In a diagnostic study of inflammatory bowel disease three classes of patients have to be diagnosed based on microarray gene-expression data. The performance of random forest is compared on a probability scale and on a classification scale to elastic net....... In survival analysis with competing risks I present an extension of random forest using time-dependent pseudo-values to build event risk prediction models. This approach is evaluated with data from Copenhagen stroke study. Further, I will explain how to use the R-package "pec" to evaluate random forests using...

  17. MRI survival guide; MRT Basiskurs

    Energy Technology Data Exchange (ETDEWEB)

    Cardoza, J. [Alta Imaging Medical Group and Magnetic Imaging Affiliates, Berkeley, CA (United States); Herfkens, R.J. [eds.] [Stanford Univ., CA (United States). Medical Center

    1999-07-01

    The book is a German translation of an American textbook with the original title ''MRI Survival Guide'' and is intended to serve as an introductory guide for beginners or a reference book for quick information. Readers will find information on the fundamentals of the technology and methodology of MRI as well as all details of relevance to practice in a precise and easy-to-grasp arrangement, covering all anatomic areas of interest, illustrations and descriptions of characteristic signs of pathologic processes, high-quality and unusually large-sized diagnostic pictures, a modern didactic concept for quick orientiation, including surveys, tables, and reproductions for visualisation of contents. (orig./CB) [German] Praktisch jeder Mediziner wird im Laufe seiner Berufstaetigkeit mit der MRT konfrontiert - unabhaengig davon ob in der Radiologie, Orthopaedie, Gynaekologie, Chirurgie, Neurologie oder sonstigen Fachrichtung. Das Buch ist eine Uebersetzung eines amerikanischen Lehrbuches mit dem Originaltitel ''MRI Survival Guide'' und will eine wesentliche Erleichterung als 'Ueberlebenshandbuch fuer die MRT' bieten: - Darstellung aller relevanten Grundlagen zu Technik, verschiedenen Sequenzen und Methodik der MRT - knapp und mit maximalem Praxisbezug - Beruecksichtigung aller moeglichen Untersuchungsregionen und strukturierte Orientierung daran (Gehirn, Wirbelsaeule, Kopf/Nacken, Brustkorb, Bauch, Becken, Muskel-Skelett-Bereich) - Illustration und Beschreibung der charakteristischen Erscheinungsmerkmale aller haeufigen pathologischen Prozesse im MRT, inklusive direkt umsetzbarer differentialdiagnostischer Abgrenzungskriterien - hochwertiges und aussergewoehnlich gross dimensioniertes Bildmaterial - modernes, didaktisches Konzept fuer die rasche Orientierung mit vielen Uebersichten, Tabellen und Abbildungen zur Visualisierung der Inhalte, Praxistips und Aufzeigen von Fehlermoeglichkeiten - zum Einstieg, zur Rekapitulation

  18. Changes in cervical cancer screening behavior for women attending Pap Test Week clinics

    Directory of Open Access Journals (Sweden)

    Poliquin V

    2013-04-01

    Full Text Available V Poliquin,1 K Decker,2,3 AD Altman,1,2,4 R Lotocki1,2,4 1Department of Obstetrics, Gynecology and Reproductive Sciences, University of Manitoba, Canada; 2CancerCare Manitoba, Winnipeg, Manitoba, Canada; 3Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, 4Division of Gynecologic Oncology, University of Manitoba, Winnipeg, Manitoba, Canada Objective: This retrospective study of all women who accessed the 2006 Manitoba Pap Test Week clinics was designed to determine factors associated with inadequate cervical cancer screening and changes in cervical cancer screening behavior. Methods: Data were acquired using the CervixCheck Manitoba registry and an ancillary database of demographic information collected from clinic attendees. Results: The study included 1124 women. Of these, 53% (n = 598 were under-screened (no Pap test in the previous 2 years prior to accessing the clinics. Logistic regression analyses demonstrated that older age (odds ratio [OR] = 1.02, 95% confidence interval [CI] 1.01–1.03, no doctor (OR = 1.4, 95% CI 1.05–1.54, and living in Canada < 1 year (OR = 5.5, 95% CI 2.73–11.12 were associated with being under-screened prior to accessing the Pap Test Week clinics. Thirty-seven percent (n = 223 of under-screened women demonstrated improved screening status subsequent to the 2006 Pap Test Week (had a subsequent Papanicolaou [Pap] test performed within 2 years and these women were more likely to live in an urban setting (P = 0.003, be younger (P < 0.001, originate outside Canada (P = 0.006, have lived in Canada for less than 1 year (P = 0.006, and have had an abnormal Pap test result in 2006 (P < 0.001. Previously under-screened women were less likely to become adequately-screened subsequent to 2006 if they had a Pap test performed at a Pap Test Week clinic compared to having a Pap test performed elsewhere (37% versus 60%, P < 0.001. Conclusion: This study identified a subset of under

  19. People who perceive themselves as active cannot identify the intensity recommended by the international physical activity guidelines

    Directory of Open Access Journals (Sweden)

    Prokop NW

    2014-10-01

    Full Text Available Neal W Prokop,1 Travis JR Hrubeniuk,1 Martin Sénéchal,2,3 Danielle R Bouchard1,4 1Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada; 2Manitoba Institute of Child Health, Winnipeg, Manitoba, Canada; 3Department of Pediatrics and Child Health, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; 4Health, Leisure, and Human Performance Research Institute, Winnipeg, Manitoba, Canada Background: Many national and international organizations recommend that adults achieve at least 150 minutes of aerobic physical activity (PA weekly, at a minimum moderate intensity to optimize health benefits. It is unknown if people who consider themselves as active have the ability to identify what is considered moderate intensity. Methods: Fifty-one participants who reported achieving a minimum 150 minutes per week at a minimum of moderate intensity PA were recruited through a local fitness facility. All participants underwent a single assessment involving questionnaires, clinical measures, and a treadmill test to measure the ability to perceive moderate intensity. Following the visit, participants' PA level was evaluated by heart rate monitor, while exercising, for 7 consecutive days. Results: Eighty percent of participants overestimated moderate intensity on the treadmill test; they were at vigorous intensity compared to what is considered moderate. Only 11.8% of participants accurately identified moderate intensity; all of them were women (P=0.03, had a high level of education (P=0.04, and knew that moderate intensity was the minimum intensity recommended by health organizations (P<0.01. Only 69.2% of participants reached the aerobic component of the International Physical Activity Guidelines with no significant advantage for those correctly identifying moderate intensity. Conclusion: Most people who perceive themselves as active are exercising at vigorous intensity while believing they are

  20. Shared Frailty Model for Left-Truncated Multivariate Survival Data

    DEFF Research Database (Denmark)

    Jensen, Henrik; Brookmeyer, Ron; Aaby, Peter

    multivariate survival data, left truncation, multiplicative hazard model, shared gamma frailty, conditional model, piecewise exponential model, childhood survival......multivariate survival data, left truncation, multiplicative hazard model, shared gamma frailty, conditional model, piecewise exponential model, childhood survival...

  1. The Survival and Birth of Firms

    OpenAIRE

    Leon Shilton; Craig Stanley

    1999-01-01

    Using a modified form of the location quotient, a "growth quotient," this study traces the survival and growth for the headquarters of publicly listed firms in the United States. At the county level, the spatial concentrations of headquarters listed in 1997 are correlated with the spatial concentrations of corporate headquarters that survived from 1986 though 1996. Counties that house the headquarters of many different survival firms continue to spawn new headquarters. Counties with headquart...

  2. Reflexive Aero Structures for Enhanced Survivability Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group Inc. (CRG) proposes to develop an advanced reflexive structure system to increase the survivability of aerostructures. This reflexive...

  3. Surviving severe traumatic brain injury in Denmark

    DEFF Research Database (Denmark)

    Odgaard, Lene; Poulsen, Ingrid; Kammersgaard, Lars Peter

    2015-01-01

    PURPOSE: To identify all hospitalized patients surviving severe traumatic brain injury (TBI) in Denmark and to compare these patients to TBI patients admitted to highly specialized rehabilitation (HS-rehabilitation). PATIENTS AND METHODS: Patients surviving severe TBI were identified from...... severe TBI were admitted to HS-rehabilitation. Female sex, older age, and non-working status pre-injury were independent predictors of no HS-rehabilitation among patients surviving severe TBI. CONCLUSION: The incidence rate of hospitalized patients surviving severe TBI was stable in Denmark...

  4. Reflexive Aero Structures for Enhanced Survivability Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group Inc. (CRG) will develop an advanced reflexive structure technology system to increase the survivability of future systems constructed of...

  5. Improving Survival in Decompensated Cirrhosis

    Directory of Open Access Journals (Sweden)

    Amar Nath Mukerji

    2012-01-01

    Full Text Available Mortality in cirrhosis is consequent of decompensation, only treatment being timely liver transplantation. Organ allocation is prioritized for the sickest patients based on Model for End Stage Liver Disease (MELD score. In order to improve survival in patients with high MELD score it is imperative to preserve them in suitable condition till transplantation. Here we examine means to prolong life in high MELD score patients till a suitable liver is available. We specially emphasize protection of airways by avoidance of sedatives, avoidance of Bilevel Positive Airway Pressure, elective intubation in grade III or higher encephalopathy, maintaining a low threshold for intubation with lesser grades of encephalopathy when undergoing upper endoscopy or colonoscopy as pre transplant evaluation or transferring patient to a transplant center. Consider post-pyloric tube feeding in encephalopathy to maintain muscle mass and minimize risk of aspiration. In non intubated and well controlled encephalopathy, frequent physical mobility by active and passive exercises are recommended. When renal replacement therapy is needed, night-time Continuous Veno-Venous Hemodialysis may be useful in keeping the daytime free for mobility. Sparing and judicious use of steroids needs to be borne in mind in treatment of ARDS and acute hepatitis from alcohol or autoimmune process.

  6. Comportements en matière de santé associés au bronzage artificiel d’après l’Enquête sur la santé des jeunes du Manitoba de 2012-2013

    Directory of Open Access Journals (Sweden)

    E. Harland

    2016-01-01

    Full Text Available Introduction : Bien que le bronzage artificiel cause le cancer, il demeure relativement courant chez les adolescents. Nous en savons peu sur les habitudes en matière de bronzage artificiel ainsi que sur la prévalence de ce dernier au Canada, et nous en savons encore moins sur les comportements associés. Cette étude se penche sur la prévalence du bronzage artificiel chez les adolescents du Manitoba ainsi que sur son association avec d’autres caractéristiques individuelles et comportements en matière de santé. Méthodologie : Nous avons effectué des analyses secondaires des données recueillies dans le cadre de l’Enquête sur la santé des jeunes du Manitoba (2012-2013 auprès d’élèves de la 7e à la 12e année (n = 64 174 et nous avons examiné les associations entre le bronzage artificiel (selon si les répondants avaient déjà utilisé des appareils de bronzage artificiel et 25 variables. Les variables présentant un lien statistiquement significatif avec le bronzage artificiel ont fait l’objet de tests pour déterminer toute colinéarité potentielle et elles ont été regroupées en fonction de la force de leurs associations. Pour chaque groupe de variables dont l’association avait une signification statistique, la variable ayant l’effet de plus grande ampleur sur le bronzage artificiel a été intégrée au modèle final de régression logistique. Des analyses séparées ont été réalisées pour les garçons et les filles afin de mieux comprendre les différences fondées sur le sexe, et les analyses ont été ajustées en fonction de l’âge. Résultats : Globalement, 4 % des garçons et 9 % des filles ont indiqué avoir eu recours au bronzage artificiel, et la prévalence augmentait avec l’âge. Les associations entre le bronzage artificiel et les autres variables étaient similaires chez les garçons et les filles. Les modèles de régression logistique binaire ont révélé que plusieurs variables pr

  7. Survival From Childhood Hematological Malignancies in Denmark

    DEFF Research Database (Denmark)

    Erdmann, Friederike; Winther, Jeanette Falck; Dalton, Susanne Oksbjerg

    2016-01-01

    .76 (CI 2.01; 16.51) were observed for the fourth or later born children with ALL (N = 41) and AML (N = 9), respectively. Children with older parents showed a tendency toward inferior ALL survival, while for AML young maternal age was related to poorer survival. Based on small numbers, a trend toward...

  8. Zimbabwe's Exodus: Crisis, Migration, Survival | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-07-01

    Zimbabwe's Exodus: Crisis, Migration, Survival. Book cover Zimbabwe's Exodus: Crisis, Migration, Survival. Editor(s):. Jonathan Crush and Daniel Tevera. Publisher(s):. Southern African Migration Programme, IDRC. July 1, 2010. ISBN: 9781920409227. 420 pages. e-ISBN: 9781552504994. Download PDF · Read the e- ...

  9. Domesticating Ugandan local earthworms: Survival of African ...

    African Journals Online (AJOL)

    3.5; E, 90±2.8 and E. eugeniae There was significant effect (P<0.05) of feeding rate on the survival of both species and the Fisher's LSD multiple comparison test also showed significant different (P<0.05) in the survival among the two species.

  10. Cancer rehabilitation: a barometer for survival?

    Science.gov (United States)

    Saotome, Takako; Klein, Linda; Faux, Steven

    2015-10-01

    This pilot study was conducted to describe the clinical features and functional outcomes of patients attending inpatient rehabilitation for cancer-related deconditioning and neurological deficits and to explore factors associated with improved survival. Using a retrospective audit, demographic characteristics, discharge outcomes, survival time, and functional status as measured by Functional Independence Measure (FIM) were recorded for 73 patients. Clinical status was estimated by Karnofsky Performance Status Scale (KPS). Cox regression was used to assess factors associated with improved survival following discharge from rehabilitation. Significant functional gains following rehabilitation were observed in total FIM (p = 0.02), motor FIM (p = 0.001), and KPS (p = 0.003). Length of survival ranged from 9.0 to 25.0 months, with 26 cases surviving to the end of study (censored). Patients scoring a total FIM of ≥80 survived significantly longer than patients scoring <80 (p = 0.002). At discharge, motor FIM scores (p = 0.004), FIM Efficiency (p = 0.001), KPS scores (p = 0.022), ambulation ability (p = 0.026), return to home (p = 0.009), and receipt of in-home services (p = 0.045) were significantly associated with improved survival. Functional improvement achieved through inpatient rehabilitation was associated with prolonged survival among cancer patients. Rehabilitation leading to improved independence among cancer patients may act as a marker of those with greater likelihood of better prognosis.

  11. Nematode survival in relation to soil moisture

    NARCIS (Netherlands)

    Simons, W.R.

    1973-01-01

    Established nematode populations are very persistent in the soil. It is known that they need sufficient soil moisture for movement, feeding and reproduction (fig. 5), and that there are adverse soil moisture conditions which they cannot survive. The influence of soil moisture on survival

  12. Socioeconomic position and survival after cervical cancer

    DEFF Research Database (Denmark)

    Ibfelt, E H; Kjær, S K; Høgdall, C

    2013-01-01

    In an attempt to decrease social disparities in cancer survival, it is important to consider the mechanisms by which socioeconomic position influences cancer prognosis. We aimed to investigate whether any associations between socioeconomic factors and survival after cervical cancer could...... be explained by socioeconomic differences in cancer stage, comorbidity, lifestyle factors or treatment....

  13. MECHANICAL TRANSMISSION AND SURVIVAL OF BACTERIAL ...

    African Journals Online (AJOL)

    jen

    The transmission of enset bacterial wilt with contaminated knives and the survival of the causal agent in soil and enset plant debris was studied ... Xanthomonas campestris pv. musacearum (Xcm) isolates were observed to survive in the soil up to. 9 days. Thereafter the .... and needle, while pathogenicity tests were carried ...

  14. Long-term survival in Patau syndrome.

    Science.gov (United States)

    Tunca, Y; Kadandale, J S; Pivnick, E K

    2001-04-01

    A female patient with an extra chromosome 13 (Patau syndrome) is described. There are only five previous reports of patients with trisomy 13 who have survived past the first decade. It is concluded that non-lethal congenital anomalies and aggressive medical care play an important role in the survival of patients with trisomy 13.

  15. EFFECT OF SALINITY ON SURVIVAL AND LARVAL ...

    African Journals Online (AJOL)

    Laboratory investigations was conducted to gain a better insight into the effect of changing salinity regime on the development and survival of Macrobrachium vollenhoveli larvae. At water temperature of 28 ± 2oC, larvae reared in the salinity range of 0 to 10 ppt showed low survival (<48%), whereas those reared at 12 ...

  16. Escherichia coli survival in waters: Temperature dependence

    Science.gov (United States)

    Knowing the survival rates of water-borne Escherichia coli is important in evaluating microbial contamination and making appropriate management decisions. E. coli survival rates are dependent on temperature, a dependency that is routinely expressed using an analogue of the Q10 mo...

  17. Relief for surviving relatives following a suicide.

    NARCIS (Netherlands)

    Oud, MJT; de Groot, MH

    2006-01-01

    Relief for surviving relatives following a suicide. - After the suicide of a 43-year-old woman with known depression, a 41-year-old paraplegic man who recently developed diarrhoea and a 41-year-old woman with probable depression with symptoms of psychosis, the general practitioners of the surviving

  18. Survival after in-hospital Cardiopulmonary Resuscitation

    Directory of Open Access Journals (Sweden)

    M Adib Hajbaghery

    2005-05-01

    Full Text Available Background: During recent years, cardiopulmonary resuscitation (CPR in hospital has received much attention. However, the survival rate of CPR in Iran’s hospitals is unknown. This study was designed to evaluate outcome of in-hospital CPR in Kashan. Methods: A longitudinal case registry study was conducted on all cases of in-hospital CPR during 6 months at 2002. Necessary data including; age, sex, underlying disease, working shift, time from cardiac arrest until initiating of CPR and until defibrillation, duration and result of CPR, frequency of tracheal intubations and time served for it were collected in a checklist. Results: In six months study, 206 cases of cardiopulmonary resuscitation attempted. The survival rate was similar for both sexes. Short-term survival observed in19.9% of cases and only 5.3% survived to discharge. Conclusions: Duration of CPR, time of the first defibrillation, response time and the location of cardiac arrest are the key predictors of survival to hospital discharge and in-hospital CPR strategies require improvement. This study promotes a national study on post CPR survival for accurate data on our performance in attention to chain of survival. KeyWords: Cardiopulmonary Resuscitation (CPR, Survival rate, Iran

  19. Racial differences in survival from gynecologic cancer.

    Science.gov (United States)

    Morgan, M A; Behbakht, K; Benjamin, I; Berlin, M; King, S A; Rubin, S C

    1996-12-01

    To determine whether survival from gynecologic cancer is different between African-American and white patients at an inner-city hospital with both a large clinic and a private service. We studied 538 patients (89 African American, 449 white) diagnosed with cervical, uterine, or ovarian cancer at a single institution from January 1, 1989 through December 31, 1993. Information was obtained on age, stage, site of disease, histology, and type of health insurance (public or commercial). Insurance coverage was used as a proxy for socioeconomic status. Overall survival was estimated by the method of Kaplan and Meier and compared by the log-rank test. Cox proportional hazard modeling was used to evaluate the effects of multiple factors on survival. African-American patients were significantly older and were more likely to have cervical cancer and public insurance than white patients. Overall survival was worse for African-American patients than for white patients (P whites, and African-American patients older than 65 years had a worse survival than whites of similar age. On multivariate analysis, only stage and insurance coverage were significant predictors of survival. African-American patients with gynecologic cancer at our institution have worse overall survival than white patients. The survival difference seems to be due predominantly to differences in socioeconomic status and stage at diagnosis.

  20. Microbial survival and odor in laundry

    DEFF Research Database (Denmark)

    Jepsen, Signe Munk; Johansen, Charlotte; Stahnke, Louise Heller

    2001-01-01

    , hydrophobic odorants [(Z)-4- heptenal, (E)-2-nonenal, and guaiacol] adhered more strongly to polyester than the acids. The odor formed by surviving skin microflora attached to textiles soiled with human sebum and sweat after laundering at 30 degreesC was studied by sensory evaluation and aroma extract......-were evaluated on cotton textile. A significant survival and transfer between textiles were found for all four test strains washed in E.U. and U.S. color detergents (without bleach), whereas no survival was observed in bleach-containing detergents. Gram-negative strains generally survived in greater numbers than...... Gram-positive strains. A greater survival was observed in U.S. detergents at U.S. conditions (30 degreesC, 12 min) than in E.U. detergents at E.U. conditions (40 degreesC, 30 min). The adhesion of odorants to cotton and polyester textiles during washing and drying was studied using six previously...

  1. Seasonal survival of adult female mottled ducks

    Science.gov (United States)

    Moon, Jena A.; Haukos, David A.; Conway, Warren C.

    2017-01-01

    The mottled duck (Anas fulgivula) is a non-migratory duck dependent on coastal habitats to meet all of its life cycle requirements in the Western Gulf Coast (WGC) of Texas and Louisiana, USA. This population of mottled ducks has experienced a moderate decline during the past 2 decades. Adult survival has been identified as an important factor influencing population demography. Previous work based on band-recovery data has provided only annual estimates of survival. We assessed seasonal patterns of female mottled duck survival from 2009 to 2012 using individuals marked with satellite platform transmitter terminals (PTTs). We used temperature and movement sensors within each PTT to indicate potential mortality events. We estimated cumulative weekly survival and ranked factors influential in patterns of mortality using known-fate modeling in Program MARK. Models included 4 predictors: week; hunting and non-hunting periods; biological periods defined as breeding, brooding, molt, and pairing; and mass at time of capture. Models containing hunt periods, during and outside the mottled duck season, comprised essentially 100% of model weights where both legal and illegal harvest had a negative influence on mottled duck survival. Survival rates were low during 2009–2011 (12–38% annual rate of survival), when compared with the long-term banding average of 53% annual survival. During 2011, survival of female mottled ducks was the lowest annual rate (12%) ever documented and coincided with extreme drought. Management actions maximizing the availability of wetlands and associated upland habitats during hunting seasons and drought conditions may increase adult female mottled duck survival.

  2. Cancer survival in Cuba, 1994-1995.

    Science.gov (United States)

    Garrote, L F; Alvarez, Y G; Babie, P T; Yi, M G; Alvarez, M G; Cicili, M L

    2011-01-01

    The population-based cancer registry in Cuba is a national cancer registry established in 1964; cancer registration is entirely done by passive methods. Data on survival from 13 cancer sites or types registered during 1994-1995 are reported. Follow-up has been carried out predominantly by passive methods, with median follow-up ranging from 13-54 months. The proportion with histologically verified diagnosis for various cancers ranged between 34-100%; death certificates only (DCOs) comprised 8-50%; 50-89% of total registered cases were included for the survival analysis. The 5-year age-standardized relative survival for selected cancers were breast (69%), colon (41%), cervix (56%), urinary bladder (64%), rectum (48%) and non-Hodgkin lymphoma (49%). The 5-year relative survival by age group showed no distinct pattern or trend, and was fluctuating. A decreasing survival with increasing clinical extent of disease was noted for all cancers studied. The data on survival trend revealed that the 5-year relative survival of most cancers diagnosed in 1994-1995 was greater than that in 1988-1989.

  3. Linking age, survival, and transit time distributions

    Science.gov (United States)

    Calabrese, Salvatore; Porporato, Amilcare

    2015-10-01

    Although the concepts of age, survival, and transit time have been widely used in many fields, including population dynamics, chemical engineering, and hydrology, a comprehensive mathematical framework is still missing. Here we discuss several relationships among these quantities by starting from the evolution equation for the joint distribution of age and survival, from which the equations for age and survival time readily follow. It also becomes apparent how the statistical dependence between age and survival is directly related to either the age dependence of the loss function or the survival-time dependence of the input function. The solution of the joint distribution equation also allows us to obtain the relationships between the age at exit (or death) and the survival time at input (or birth), as well as to stress the symmetries of the various distributions under time reversal. The transit time is then obtained as a sum of the age and survival time, and its properties are discussed along with the general relationships between their mean values. The special case of steady state case is analyzed in detail. Some examples, inspired by hydrologic applications, are presented to illustrate the theory with the specific results. This article was corrected on 11 Nov 2015. See the end of the full text for details.

  4. Survival analysis of orthodontic mini-implants.

    Science.gov (United States)

    Lee, Shin-Jae; Ahn, Sug-Joon; Lee, Jae Won; Kim, Seong-Hun; Kim, Tae-Woo

    2010-02-01

    Survival analysis is useful in clinical research because it focuses on comparing the survival distributions and the identification of risk factors. Our aim in this study was to investigate the survival characteristics and risk factors of orthodontic mini-implants with survival analyses. One hundred forty-one orthodontic patients (treated from October 1, 2000, to November 29, 2007) were included in this survival study. A total of 260 orthodontic mini-implants that had sandblasted (large grit) and acid-etched screw parts were placed between the maxillary second premolar and the first molar. Failures of the implants were recorded as event data, whereas implants that were removed because treatment ended and those that were not removed during the study period were recorded as censored data. A nonparametric life table method was used to visualize the hazard function, and Kaplan-Meier survival curves were generated to identify the variables associated with implant failure. Prognostic variables associated with implant failure were identified with the Cox proportional hazard model. Of the 260 implants, 22 failed. The hazard function for implant failure showed that the risk is highest immediately after placement. The survival function showed that the median survival time of orthodontic mini-implants is sufficient for relatively long orthodontic treatments. The Cox proportional hazard model identified that increasing age is a decisive factor for implant survival. The decreasing pattern of the hazard function suggested gradual osseointegration of orthodontic mini-implants. When implants are placed in a young patient, special caution is needed to lessen the increased probability of failure, especially immediately after placement.

  5. Foreign Ownership and long-term Survival

    OpenAIRE

    Kronborg, Dorte; Thomsen, Steen

    2006-01-01

    Does foreign ownership enhance or decrease a firm’s chances of survival? Over the 100 year period 1895-2001 this paper compares the survival of foreign subsidiaries in Denmark to a control sample matched by industry and firm size. We find that foreign-owned companies have higher survival probability. On average exit risk for domestic companies is 2.3 times higher than for foreign companies. First movers like Siemens, Philips, Kodak, Ford, GM or Goodyear have been active in the country for alm...

  6. Controlling chaotic transients: Yorke's game of survival

    DEFF Research Database (Denmark)

    Aguirre, Jacobo; D'ovidio, Francesco; Sanjuán, Miguel A. F.

    2004-01-01

    . This problem is focused as a two-person, mathematical game between two players called "the protagonist" and "the adversary." The protagonist's goal is to survive. He can lose but cannot win; the best he can do is survive to play another round, struggling ad infinitum. In the absence of actions by either player...... knows the action of the adversary in choosing his response and is permitted to choose the initial point x(0) of the game. We use the "slope 3" tent map in an example of this problem. We show that it is possible for the protagonist to survive....

  7. Empirical likelihood method in survival analysis

    CERN Document Server

    Zhou, Mai

    2015-01-01

    Add the Empirical Likelihood to Your Nonparametric ToolboxEmpirical Likelihood Method in Survival Analysis explains how to use the empirical likelihood method for right censored survival data. The author uses R for calculating empirical likelihood and includes many worked out examples with the associated R code. The datasets and code are available for download on his website and CRAN.The book focuses on all the standard survival analysis topics treated with empirical likelihood, including hazard functions, cumulative distribution functions, analysis of the Cox model, and computation of empiric

  8. The burden of cancer risk in Canada's indigenous population: a comparative study of known risks in a Canadian region

    Directory of Open Access Journals (Sweden)

    Elias B

    2011-10-01

    Full Text Available Brenda Elias1, Erich V Kliewer1–3, Madelyn Hall1, Alain A Demers1,2, Donna Turner1,2, Patricia Martens1, Say P Hong1, Lyna Hart4, Caroline Chartrand5, Garry Munro41Faculty of Medicine, Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada; 2CancerCare Manitoba, Winnipeg, MB, Canada; 3British Columbia Cancer Agency, Vancouver, BC, Canada; 4Assembly of Manitoba Chiefs Health Information Research Governance Committee, Winnipeg, MB, Canada; 5Manitoba First Nations Diabetes Integration Project, Winnipeg, MB, CanadaBackground: Canadian First Nations, the largest of the Aboriginal groups in Canada, have had lower cancer incidence and mortality rates than non-Aboriginal populations in the past. This pattern is changing with increased life expectancy, a growing population, and a poor social environment that influences risk behaviors, metabolic conditions, and disparities in screening uptake. These factors alone do not fully explain differences in cancer risk between populations, as genetic susceptibility and environmental factors also have significant influence. However, genetics and environment are difficult to modify. This study compared modifiable behavioral risk factors and metabolic-associated conditions for men and women, and cancer screening practices of women, between First Nations living on-reserve and a non-First Nations Manitoba rural population (Canada.Methods: The study used data from the Canadian Community Health Survey and the Manitoba First Nations Regional Longitudinal Health Survey to examine smoking, binge drinking, metabolic conditions, physical activity, fruit/vegetable consumption, and cancer-screening practices.Results: First Nations on-reserve had significantly higher rates of smoking (P < 0.001, binge drinking (P < 0.001, obesity (P < 0.001 and diabetes (P < 0.001, and less leisure-time physical activity (P = 0.029, and consumption of fruits and vegetables (P < 0.001. Sex differences were also

  9. Ministerial Importance and Survival in Government

    DEFF Research Database (Denmark)

    Bright, Jonathan; Döring, Holger; Little, Conor

    2015-01-01

    Are holders of important ministerial positions more likely to survive in cabinet than their colleagues who hold less important positions? This study examines the relationship between the importance of a ministerial position and the length of time ministers are able to survive in government....... It is based on an original dataset of cabinet ministers in seven West European countries from 1945 to 2011. Employing a little-used measure of ministerial survival based on overall time in government, it is found that holders of important ministerial positions are more durable than their colleagues who hold...... less important ministerial positions. Age, prior government experience and the size of the party to which the minister belongs are also associated with consistently significant effects. Further, the study explores the determinants of survival for two types of risk – exiting government with one’s party...

  10. SURVIVAL OF SALMONELLA SPECIES IN RIVER WATER.

    Science.gov (United States)

    The survival of four Salmonella strains in river water microcosms was monitored using culturing techniques, direct counts, whole cell hybridization, scanning electron microscopy, and resuscitation techniques via the direct viable count method and flow cytrometry. Plate counts of...

  11. Surviving Sepsis: Taming a Deadly Immune Response

    Science.gov (United States)

    ... Issues Subscribe August 2014 Print this issue Surviving Sepsis Taming a Deadly Immune Response En español Send ... Mouth? Looking at Lupus Wise Choices Signs of Sepsis Sepsis can be hard to spot, because its ...

  12. Cognitive function in families with exceptional survival

    DEFF Research Database (Denmark)

    Barral, Sandra; Cosentino, Stephanie; Costa, Rosann

    2012-01-01

    members in the offspring generation demonstrate significantly better performance on multiple tasks requiring attention, working memory, and semantic processing when compared with individuals without a family history of exceptional survival, suggesting that cognitive performance may serve as an important...

  13. Bay Scallop Spawning, Survival, Growth Records

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Bay Scallops are selected and cultured according to criteria of growth and survival. Morphological attributes have also been selected to assess heretibility....

  14. Zooplankton Data - Ocean Survival of Salmonids

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A study to evaluate the role of changing ocean conditions on growth and survival of juvenile salmon from the Columbia River basin as they enter the Columbia River...

  15. Juvenile Salmonid Metrics - Ocean Survival of Salmonids

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A study to evaluate the role of changing ocean conditions on growth and survival of juvenile salmon from the Columbia River basin as they enter the Columbia River...

  16. Oceanographic Trawl Data - Ocean Survival of Salmonids

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A study to evaluate the role of changing ocean conditions on growth and survival of juvenile salmon from the Columbia River basin as they enter the Columbia River...

  17. CTD Oceanographic Data - Ocean Survival of Salmonids

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A study to evaluate the role of changing ocean conditions on growth and survival of juvenile salmon from the Columbia River basin as they enter the Columbia River...

  18. Abiraterone Improves Survival in Metastatic Prostate Cancer

    Science.gov (United States)

    A multinational phase III trial found that the drug abiraterone acetate prolonged the median survival of patients with metastatic castration-resistant prostate cancer by 4 months compared with patients who received a placebo.

  19. New Firm Survival: Industry versus Firm Effects

    NARCIS (Netherlands)

    D.B. Audretsch (David); P. Houweling (Patrick); A.R. Thurik (Roy)

    1997-01-01

    textabstractRecent studies show that the likelihood of survival differs significantly across firms. Both firm and industry characteristics are hypothesized to account for this heterogenity. Using a longitudinal database of manufacturing firms we investigate whether firm or industry characteristics

  20. FCS Vehicle Transportability, Survivability, and Reliability Analysis

    National Research Council Canada - National Science Library

    Dion-Schwarz, Cynthia; Hirsch, Leon; Koehn, Phillip; Macheret, Jenya; Sparrow, Dave

    2005-01-01

    .... The investigation into metrics for transportability revealed that the C130 Transportability requirement for FCS vehicles is a constraint that leads to a less survivable platform but without improving Unit of Action (UA) transportability...

  1. HMSRP Hawaiian Monk Seal Survival Factors

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains records of survival factors recorded by PSD personnel and cooperating scientists as part of the ongoing monk seal population assessment...

  2. Modelling population-based cancer survival trends using join point models for grouped survival data.

    Science.gov (United States)

    Yu, Binbing; Huang, Lan; Tiwari, Ram C; Feuer, Eric J; Johnson, Karen A

    2009-04-01

    In the United States cancer as a whole is the second leading cause of death and a major burden to health care, thus the medical progress against cancer is a major public health goal. There are many individual studies to suggest that cancer treatment breakthroughs and early diagnosis have significantly improved the prognosis of cancer patients. To better understand the relationship between medical improvements and the survival experience for the patient population at large, it is useful to evaluate cancer survival trends on the population level, e.g., to find out when and how much the cancer survival rates changed. In this paper, we analyze the population-based grouped cancer survival data by incorporating joinpoints into the survival models. A joinpoint survival model facilitates the identification of trends with significant change points in cancer survival, when related to cancer treatments or interventions. The Bayesian Information Criterion is used to select the number of joinpoints. The performance of the joinpoint survival models is evaluated with respect to cancer prognosis, joinpoint locations, annual percent changes in death rates by year of diagnosis, and sample sizes through intensive simulation studies. The model is then applied to the grouped relative survival data for several major cancer sites from the Surveillance, Epidemiology and End Results (SEER) Program of the National Cancer Institute. The change points in the survival trends for several major cancer sites are identified and the potential driving forces behind such change points are discussed.

  3. Relevance Vector Machine for Survival Analysis.

    Science.gov (United States)

    Kiaee, Farkhondeh; Sheikhzadeh, Hamid; Mahabadi, Samaneh Eftekhari

    2016-03-01

    An accelerated failure time (AFT) model has been widely used for the analysis of censored survival or failure time data. However, the AFT imposes the restrictive log-linear relation between the survival time and the explanatory variables. In this paper, we introduce a relevance vector machine survival (RVMS) model based on Weibull AFT model that enables the use of kernel framework to automatically learn the possible nonlinear effects of the input explanatory variables on target survival times. We take advantage of the Bayesian inference technique in order to estimate the model parameters. We also introduce two approaches to accelerate the RVMS training. In the first approach, an efficient smooth prior is employed that improves the degree of sparsity. In the second approach, a fast marginal likelihood maximization procedure is used for obtaining a sparse solution of survival analysis task by sequential addition and deletion of candidate basis functions. These two approaches, denoted by smooth RVMS and fast RVMS, typically use fewer basis functions than RVMS and improve the RVMS training time; however, they cause a slight degradation in the RVMS performance. We compare the RVMS and the two accelerated approaches with the previous sparse kernel survival analysis method on a synthetic data set as well as six real-world data sets. The proposed kernel survival analysis models have been discovered to be more accurate in prediction, although they benefit from extra sparsity. The main advantages of our proposed models are: 1) extra sparsity that leads to a better generalization and avoids overfitting; 2) automatic relevance sample determination based on data that provide more accuracy, in particular for highly censored survival data; and 3) flexibility to utilize arbitrary number and types of kernel functions (e.g., non-Mercer kernels and multikernel learning).

  4. Minding the body: psychotherapy and cancer survival.

    Science.gov (United States)

    Spiegel, David

    2014-09-01

    This article reviews evidence regarding effects of psychotherapy on overall cancer survival time. Special emphasis is given to research on adverse effects of depression on cancer survival, breast cancer, and mediating psychophysiological pathways linking psychosocial support to longer survival. It reviews all published clinical trials addressing effects of psychotherapy on cancer survival, emphasizing depression, breast cancer, and psychophysiological evidence linking stress, depression, and support to cancer survival. Systematic literature review and synthesis. Eight of 15 published trials indicate that psychotherapy enhances cancer survival time. No studies show an adverse effect of psychotherapy on cancer survival. Potential psychophysiological mechanisms linking stress to shorter survival include dysregulation of diurnal cortisol, increased pro-inflammatory cytokines, reduced natural killer cell activity, shorter telomeres and lower telomerase activity, glucocorticoid-mediated suppression of p53 and BrCA1 gene expression, and sympathetic nervous system activation of vascular endothelial growth factor. Stress and support affect the course of cancer progression. What is known? Stress and support have been thought to be related to cancer risk and progression, but evidence has been mixed. Depression is a natural co-morbid condition with cancer. It has not been clear how stress and support could physiologically affect the rate of cancer progression. Immune function was not thought to have much relevance to cancer progression. Few other physiological mechanisms linking stress to cancer progression were known. What does this paper add? There is evidence from 15 RCTs indicating that effective psychosocial support improves quantity as well as quality of life with cancer. There is evidence that chronic depression predicts poorer prognosis with cancer. Dysregulated circadian cortisol patterns predict more rapid cancer progression. Inflammatory processes affect cancer

  5. Helping mothers survive bleeding after birth

    DEFF Research Database (Denmark)

    Nelissen, Ellen; Ersdal, Hege; Ostergaard, Doris

    2014-01-01

    OBJECTIVE: To evaluate "Helping Mothers Survive Bleeding After Birth" (HMS BAB) simulation-based training in a low-resource setting. DESIGN: Educational intervention study. SETTING: Rural referral hospital in Northern Tanzania. POPULATION: Clinicians, nurse-midwives, medical attendants, and ambul......OBJECTIVE: To evaluate "Helping Mothers Survive Bleeding After Birth" (HMS BAB) simulation-based training in a low-resource setting. DESIGN: Educational intervention study. SETTING: Rural referral hospital in Northern Tanzania. POPULATION: Clinicians, nurse-midwives, medical attendants...

  6. Survival of Burkholderia pseudomallei in Water

    Directory of Open Access Journals (Sweden)

    Woods Donald E

    2008-05-01

    Full Text Available Abstract Background The ability of Burkholderia pseudomallei to survive in water likely contributes to its environmental persistence in endemic regions. To determine the physiological adaptations which allow B. pseudomallei to survive in aqueous environments, we performed microarray analyses of B. pseudomallei cultures transferred from Luria broth (LB to distilled water. Findings Increased expression of a gene encoding for a putative membrane protein (BPSL0721 was confirmed using a lux-based transcriptional reporter system, and maximal expression was noted at approximately 6 hrs after shifting cells from LB to water. A BPSL0721 deficient mutant of B. pseudomallei was able to survive in water for at least 90 days indicating that although involved, BPSL0721 was not essential for survival. BPSL2961, a gene encoding a putative phosphatidylglycerol phosphatase (PGP, was also induced when cells were shifted to water. This gene is likely involved in cell membrane biosynthesis. We were unable to construct a PGP mutant suggesting that the gene is not only involved in survival in water but is essential for cell viability. We also examined mutants of polyhydroxybutyrate synthase (phbC, lipopolysaccharide (LPS oligosaccharide and capsule synthesis, and these mutations did not affect survival in water. LPS mutants lacking outer core were found to lose viability in water by 200 days indicating that an intact LPS core provides an outer membrane architecture which allows prolonged survival in water. Conclusion The results from these studies suggest that B. pseudomallei survival in water is a complex process that requires an LPS molecule which contains an intact core region.

  7. Evolution and Survival of Quantum Entanglement

    Science.gov (United States)

    2015-05-06

    independently for tasks of  quantum  information. These include  quantum  computing,  quantum   cryptography ,  quantum  teleportation and other forms of entanglement...Evolution and Survival of Quantum Entanglement Theoretical foundations for methods to preserve quantum entanglement are explored and explained...Research Triangle Park, NC 27709-2211 quantum entanglement, decoherence, qubit, revival, survival, Jaynes-Cummings, Rabi, rotating wave approximation

  8. Survival function of hypo-exponential distributions

    OpenAIRE

    Lotfy, Mamdouh M.; Abdelsamad, Ali S.

    1985-01-01

    Approved for public release; distribution is unlimited The reliability of a system is the probability that the system will survive or complete an intended mission of certain duration. Describing all possible ways that a system can survive a mission in reliability shorthand gives a simple approach to reliability computations. Reliability computation for a system defined by shorthand notation is greatly dependent upon the convolution problem. Assuming constant component failure rates, this p...

  9. Retrofiting survivability of military vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Canavan, Gregory H [Los Alamos National Laboratory

    2009-01-01

    of 0.5. Over the range from 0.5 to 4.5 cm the shock KE is attenuated by a factor of {approx}70, while its momentum is changed little. The shock and particle velocity falls by a factor of 200 while the mass increases by a factor of 730. In the limit of very porous media u {approx} 1/M, so KE {approx} 1/M, which falls by a factor of {approx}600, while momentum Mu does not change at all. Figure 2 shows the KE, Mu, u, and M for a material with a porosity of 1.05, for which the KE changes little. In the limit of media of very low porosity, u {approx} 1/{radical}M, so KE is constant while Mu {approx} {radical}M, which increases by a factor of 15. Thus, if the goal is to reduce the peak pressure from strong explosions below, very porous materials, which strongly reduce pressure but do not increase momentum, are preferred to non-porous materials, which amplify momentum but do not decrease pressure. These predictions are in qualitative accord with the results of experiments at Los Alamos in which projectiles from high velocity, large caliber cannons were stopped by one to two sandbags. The studies were performed primarily to determine the effectiveness of sand in stopping fragments of various sizes, but could be extended to study sand's effectiveness in attenuating blast pressure. It would also be useful to test the above predictions on the effectiveness of media with higher porosity. Water barriers have been discussed but not deployed in previous retrofit survivability studies for overseas embassies. They would detect the flash from the mine detonation below, trigger a thin layer of explosive above a layer of water, and drive water droplets into the approaching blast wave. The blast loses energy in evaporating the droplets and loses momentum in slowing them. Under favorable conditions that could attenuate the pressure in the blast enough to prevent the penetration or disruption of the vehicle. However, such barriers would depend on prompt and reliable detonation

  10. The survival of Coxiella burnetii in soils

    Science.gov (United States)

    Evstigneeva, A. S.; Ul'Yanova, T. Yu.; Tarasevich, I. V.

    2007-05-01

    Coxiella burnetii is a pathogen of Q-fever—a widespread zoonosis. The effective adaptation of C. burnetii to intracellular existence is in contrast with its ability to survive in the environment outside the host cells and its resistance to chemical and physical agents. Its mechanism of survival remains unknown. However, its survival appears to be related to the developmental cycle of the microorganism itself, i.e., to the formation of its dormant forms. The survival of Coxiella burnetii was studied for the first time. The pathogenic microorganism was inoculated into different types of soil and cultivated under different temperatures. The survival of the pathogen was verified using a model with laboratory animals (mice). Viable C. burnetii were found in the soil even 20 days after their inoculation. The relationship between the organic carbon content in the soils and the survival of C. burnetii was revealed. Thus, the results obtained were the first to demonstrate that the soil may serve as a reservoir for the preservation and further spreading of the Q-fever pathogen in the environment, on the one hand, and reduce the risk of epidemics, on the other.

  11. Tooth survival after root canal treatment.

    Science.gov (United States)

    Balto, Khaled

    2011-01-01

    Medline, the Cochrane Library, hand searches of the International Endodontic Journal, Journal of Endodontics, Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics, Dental Traumatology (& Endodontics) and bibliographies of all relevant articles and review articles. Unpublished studies were identified by searching abstracts and conference proceedings. Personal contacts were used to identify ongoing or unpublished studies. Two reviewers independently assessed and selected the studies with disagreements being resolved by discussion. Clinical studies of RCTx on more than 30 teeth and of at least six-month duration, where the success was based on survival of tooth and the proportion of teeth surviving was given, or could be calculated from the raw data, were included. Data were extracted by two reviewers independently using custom-designed forms. The weighted pooled proportion of teeth surviving after treatment and the combined effects (expressed as odds ratio) of clinical factors on tooth survival were estimated using fixed and random effects meta-analyses using DerSimonean and Laird's methods. The survival data were pooled into three groups based on the duration after treatment: 2 or 3 years; 4 or 5 years; and 8, 9 or 10 years. Statistical heterogeneity amongst the studies was assessed by Cochran's (Q) test. Of the 31 articles identified, 14 studies were included. The majority (10) were retrospective. The reported survival is shown in Table 1. Substantial differences in study characteristics were found to hinder effective direct comparison of findings. Evidence for the effect of prognostic factors on tooth survival was weak. Based on the data available for meta-analysis, four conditions were found to significantly improve tooth survival. In descending order of influence, the conditions increasing observed proportion of survival were as follows: (i) a crown restoration after RCTx; (ii) tooth having both mesial and distal proximal contacts; (iii

  12. Challenges in the estimation of Net SURvival: The CENSUR working survival group.

    Science.gov (United States)

    Giorgi, R

    2016-10-01

    Net survival, the survival probability that would be observed, in a hypothetical world, where the cancer of interest would be the only possible cause of death, is a key indicator in population-based cancer studies. Accounting for mortality due to other causes, it allows cross-country comparisons or trends analysis and provides a useful indicator for public health decision-making. The objective of this study was to show how the creation and formalization of a network comprising established research teams, which already had substantial and complementary experience in both cancer survival analysis and methodological development, make it possible to meet challenges and thus provide more adequate tools, to improve the quality and the comparability of cancer survival data, and to promote methodological transfers in areas of emerging interest. The Challenges in the Estimation of Net SURvival (CENSUR) working survival group is composed of international researchers highly skilled in biostatistics, methodology, and epidemiology, from different research organizations in France, the United Kingdom, Italy, Slovenia, and Canada, and involved in French (FRANCIM) and European (EUROCARE) cancer registry networks. The expected advantages are an interdisciplinary, international, synergistic network capable of addressing problems in public health, for decision-makers at different levels; tools for those in charge of net survival analyses; a common methodology that makes unbiased cross-national comparisons of cancer survival feasible; transfer of methods for net survival estimations to other specific applications (clinical research, occupational epidemiology); and dissemination of results during an international training course. The formalization of the international CENSUR working survival group was motivated by a need felt by scientists conducting population-based cancer research to discuss, develop, and monitor implementation of a common methodology to analyze net survival in order

  13. Five-year survival and median survival time of nasopharyngeal carcinoma in Hospital Universiti Sains Malaysia.

    Science.gov (United States)

    Siti-Azrin, Ab Hamid; Norsa'adah, Bachok; Naing, Nyi Nyi

    2014-01-01

    Nasopharyngeal carcinoma (NPC) is the fourth most common cancer in Malaysia. The objective of this study was to determine the five-year survival rate and median survival time of NPC patients in Hospital Universiti Sains Malaysia (USM). One hundred and thirty four NPC cases confirmed by histopathology in Hospital USM between 1st January 1998 and 31st December 2007 that fulfilled the inclusion and exclusion criteria were retrospectively reviewed. Survival time of NPC patients were estimated by Kaplan-Meier survival analysis. Log-rank tests were performed to compare survival of cases among presenting symptoms, WHO type, TNM classification and treatment modalities. The overall five-year survival rate of NPC patients was 38.0% (95% confidence interval (CI): 29.1, 46.9). The overall median survival time of NPC patients was 31.30 months (95%CI: 23.76, 38.84). The significant factors that altered the survival rate and time were age (p=0.041), cranial nerve involvement (p=0.012), stage (p=0.002), metastases (p=0.008) and treatment (p<0.001). The median survival of NPC patients is significantly longer for age≤50 years, no cranial nerve involvement, and early stage and is dependent on treatment modalities.

  14. Survivability is more fundamental than evolvability.

    Directory of Open Access Journals (Sweden)

    Michael E Palmer

    Full Text Available For a lineage to survive over long time periods, it must sometimes change. This has given rise to the term evolvability, meaning the tendency to produce adaptive variation. One lineage may be superior to another in terms of its current standing variation, or it may tend to produce more adaptive variation. However, evolutionary outcomes depend on more than standing variation and produced adaptive variation: deleterious variation also matters. Evolvability, as most commonly interpreted, is not predictive of evolutionary outcomes. Here, we define a predictive measure of the evolutionary success of a lineage that we call the k-survivability, defined as the probability that the lineage avoids extinction for k generations. We estimate the k-survivability using multiple experimental replicates. Because we measure evolutionary outcomes, the initial standing variation, the full spectrum of generated variation, and the heritability of that variation are all incorporated. Survivability also accounts for the decreased joint likelihood of extinction of sub-lineages when they 1 disperse in space, or 2 diversify in lifestyle. We illustrate measurement of survivability with in silico models, and suggest that it may also be measured in vivo using multiple longitudinal replicates. The k-survivability is a metric that enables the quantitative study of, for example, the evolution of 1 mutation rates, 2 dispersal mechanisms, 3 the genotype-phenotype map, and 4 sexual reproduction, in temporally and spatially fluctuating environments. Although these disparate phenomena evolve by well-understood microevolutionary rules, they are also subject to the macroevolutionary constraint of long-term survivability.

  15. SURVIVAL ANALYSIS AND LENGTH-BIASED SAMPLING

    Directory of Open Access Journals (Sweden)

    Masoud Asgharian

    2010-12-01

    Full Text Available When survival data are colleted as part of a prevalent cohort study, the recruited cases have already experienced their initiating event. These prevalent cases are then followed for a fixed period of time at the end of which the subjects will either have failed or have been censored. When interests lies in estimating the survival distribution, from onset, of subjects with the disease, one must take into account that the survival times of the cases in a prevalent cohort study are left truncated. When it is possible to assume that there has not been any epidemic of the disease over the past period of time that covers the onset times of the subjects, one may assume that the underlying incidence process that generates the initiating event times is a stationary Poisson process. Under such assumption, the survival times of the recruited subjects are called “lengthbiased”. I discuss the challenges one is faced with in analyzing these type of data. To address the theoretical aspects of the work, I present asymptotic results for the NPMLE of the length-biased as well as the unbiased survival distribution. I also discuss estimating the unbiased survival function using only the follow-up time. This addresses the case that the onset times are either unknown or known with uncertainty. Some of our most recent work and open questions will be presented. These include some aspects of analysis of covariates, strong approximation, functional LIL and density estimation under length-biased sampling with right censoring. The results will be illustrated with survival data from patients with dementia, collected as part of the Canadian Study of Health and Aging (CSHA.

  16. Attenuation caused by infrequently updated covariates in survival analysis

    DEFF Research Database (Denmark)

    Andersen, Per Kragh; Liestøl, Knut

    2003-01-01

    Attenuation; Cox regression model; Measurement errors; Survival analysis; Time-dependent covariates......Attenuation; Cox regression model; Measurement errors; Survival analysis; Time-dependent covariates...

  17. Multidimensional Poverty and Child Survival in India

    Science.gov (United States)

    Mohanty, Sanjay K.

    2011-01-01

    Background Though the concept of multidimensional poverty has been acknowledged cutting across the disciplines (among economists, public health professionals, development thinkers, social scientists, policy makers and international organizations) and included in the development agenda, its measurement and application are still limited. Objectives and Methodology Using unit data from the National Family and Health Survey 3, India, this paper measures poverty in multidimensional space and examine the linkages of multidimensional poverty with child survival. The multidimensional poverty is measured in the dimension of knowledge, health and wealth and the child survival is measured with respect to infant mortality and under-five mortality. Descriptive statistics, principal component analyses and the life table methods are used in the analyses. Results The estimates of multidimensional poverty are robust and the inter-state differentials are large. While infant mortality rate and under-five mortality rate are disproportionately higher among the abject poor compared to the non-poor, there are no significant differences in child survival among educationally, economically and health poor at the national level. State pattern in child survival among the education, economical and health poor are mixed. Conclusion Use of multidimensional poverty measures help to identify abject poor who are unlikely to come out of poverty trap. The child survival is significantly lower among abject poor compared to moderate poor and non-poor. We urge to popularize the concept of multiple deprivations in research and program so as to reduce poverty and inequality in the population. PMID:22046384

  18. Survival of pneumococcus on hands and fomites

    Directory of Open Access Journals (Sweden)

    Beissbarth Jemima

    2008-11-01

    Full Text Available Abstract Background Pneumococcal hand contamination in Indigenous children in remote communities is common (37%. It is not clear whether this requires frequent inoculation, or if pneumococci will survive on hands for long periods of time. Thus the aim of this study was to determine the survival time of pneumococci on hands and fomites. Findings The hands of 3 adult volunteers, a glass plate and plastic ball were inoculated with pneumococci suspended in two different media. Survival at specified time intervals was determined by swabbing and re-culture onto horse blood agar. Pneumococci inoculated onto hands of volunteers were recovered after 3 minutes at 4% to 79% of the initial inoculum. Recovery from one individual was consistently higher. By one hour, only a small number of pneumococci were recovered and this was dependent on the suspension medium used. At subsequent intervals and up to 3 hours after inoculation, Conclusion The poor survival of pneumococci on hands suggests that the high prevalence of pneumococcal hand contamination in some populations is related to frequent inoculation rather than long survival. It is plausible that hand contamination plays a (brief role in transmission directly, and indirectly through contamination via fomites. Regular hand washing and timely cleansing or removal of contaminated fomites may aid control of pneumococcal transmission via these routes.

  19. Incidence and overall survival of malignant ameloblastoma.

    Directory of Open Access Journals (Sweden)

    Alexandra Rizzitelli

    Full Text Available Malignant ameloblastoma, comprising metastasizing ameloblastoma and ameloblastic carcinoma, represents 1.6-2.2% of all odontogenic tumors. Due to its rare nature, malignant ameloblastoma has only been reported in the literature in small case series or case reports. Using the Surveillance, Epidemiology and End-Results (SEER database, we have performed a population-based study to determine the incidence rate and the absolute survival of malignant ameloblastoma.Using the International Classification of Diseases for Oncology (ICD-O codes 9310/3 and 9270/3, data from the SEER database were used to calculate the incidence rate and absolute survival rate of population with malignant ameloblastoma.The overall incidence rate of malignant ameloblastoma was 1.79 per 10 million person/year. The incidence rate was higher in males than females and also higher in black versus white population. The median overall survival was 17.6 years from the time of diagnosis and increasing age was associated with a statistically significant poorer survival.To our best knowledge, we report the largest population-based series of malignant ameloblastoma. The incidence rate was 1.79 per 10 million person/year and the overall survival was 17.6 years.

  20. Survivability of a metapopulation under local extinctions

    Science.gov (United States)

    Kundu, Srilena; Majhi, Soumen; Sasmal, Sourav Kumar; Ghosh, Dibakar; Rakshit, Biswambhar

    2017-12-01

    A metapopulation structure in landscape ecology comprises a group of interacting spatially separated subpopulations or patches of the same species that may experience several local extinctions. This makes the investigation of survivability (in the form of global oscillation) of a metapopulation on top of diverse dispersal topologies extremely crucial. However, among various dispersal topologies in ecological networks, which one can provide higher metapopulation survivability under local extinction is still not well explored. In this article, we scrutinize the robustness of an ecological network consisting of prey-predator patches having Holling type I functional response, against progressively extinct population patches. We present a comprehensive study on this while considering global, small-world, and scale-free dispersal of the subpopulations. Furthermore, we extend our work in enhancing survivability in the form of sustained global oscillation by introducing asymmetries in the dispersal rates of the considered species. Our findings affirm that the asynchrony among the patches plays an important role in the survivability of a metapopulation. In order to demonstrate the model independence of the observed phenomenon, we perform a similar analysis for patches exhibiting Holling type II functional response. On the grounds of the obtained results, our work is expected to provide a better perception of the influence of dispersal arrangements on the global survivability of ecological networks.

  1. Multidimensional poverty and child survival in India.

    Science.gov (United States)

    Mohanty, Sanjay K

    2011-01-01

    Though the concept of multidimensional poverty has been acknowledged cutting across the disciplines (among economists, public health professionals, development thinkers, social scientists, policy makers and international organizations) and included in the development agenda, its measurement and application are still limited. OBJECTIVES AND METHODOLOGY: Using unit data from the National Family and Health Survey 3, India, this paper measures poverty in multidimensional space and examine the linkages of multidimensional poverty with child survival. The multidimensional poverty is measured in the dimension of knowledge, health and wealth and the child survival is measured with respect to infant mortality and under-five mortality. Descriptive statistics, principal component analyses and the life table methods are used in the analyses. The estimates of multidimensional poverty are robust and the inter-state differentials are large. While infant mortality rate and under-five mortality rate are disproportionately higher among the abject poor compared to the non-poor, there are no significant differences in child survival among educationally, economically and health poor at the national level. State pattern in child survival among the education, economical and health poor are mixed. Use of multidimensional poverty measures help to identify abject poor who are unlikely to come out of poverty trap. The child survival is significantly lower among abject poor compared to moderate poor and non-poor. We urge to popularize the concept of multiple deprivations in research and program so as to reduce poverty and inequality in the population.

  2. Regression analysis of restricted mean survival time based on pseudo-observations

    DEFF Research Database (Denmark)

    Andersen, Per Kragh; Hansen, Mette Gerster; Klein, John P.

    censoring; hazard function; health economics; regression model; survival analysis; mean survival time; restricted mean survival time; pseudo-observations......censoring; hazard function; health economics; regression model; survival analysis; mean survival time; restricted mean survival time; pseudo-observations...

  3. Regression Analysis of Restricted Mean Survival Time Based on Pseudo-Observations

    DEFF Research Database (Denmark)

    Andersen, Per Kragh; Hansen, Mette Gerster; Klein, John P.

    2004-01-01

    censoring; hazard function; health economics; mean survival time; pseudo-observations; regression model; restricted mean survival time; survival analysis......censoring; hazard function; health economics; mean survival time; pseudo-observations; regression model; restricted mean survival time; survival analysis...

  4. Physical activity and survival in breast cancer

    DEFF Research Database (Denmark)

    Ammitzbøll, Gunn; Søgaard, Karen; Karlsen, Randi V

    2016-01-01

    the Diet, Cancer, and Health cohort, all enrolled before diagnosis. Self-reported PA was measured as time per activity, and estimated metabolic equivalent task (MET)-hours per week were summed for each activity. We constructed measures for household, exercise, and total PA. The association between......PURPOSE: Knowledge about lifestyle factors possibly influencing survival after breast cancer (BC) is paramount. We examined associations between two types of postdiagnosis physical activity (PA) and overall survival after BC. PATIENTS AND METHODS: We used prospective data on 959 BC survivors from...... from all causes during the study period. In adjusted analyses, exercise PA above eight MET h/week compared to lower levels of activity was significantly associated with improved overall survival (HR, 0.68; confidence interval [CI]: 0.47-0.99). When comparing participation in exercise to non...

  5. Survivability of systems under multiple factor impact

    Energy Technology Data Exchange (ETDEWEB)

    Korczak, Edward [Telecommunications Research Institute, Warsaw (Poland); Levitin, Gregory [Israel Electric Corporation Ltd., Haifa (Israel)]. E-mail: levitin@iec.co.il

    2007-02-15

    The paper considers vulnerable multi-state series-parallel systems operating under influence of external impacts. Both the external impacts and internal failures affect system survivability, which is determined as the probability of meeting a given demand. The external impacts are characterized by several destructive factors affecting the system or its parts simultaneously. In order to increase the system's survivability a multilevel protection against the destructive factors can be applied to its subsystems. In such systems, the protected subsystems can be destroyed only if all of the levels of their protection are destroyed. The paper presents an algorithm for evaluating the survivability of series-parallel systems with arbitrary configuration of multilevel protection against multiple destructive factor impacts. The algorithm is based on a composition of Boolean and the Universal Generating Function techniques. Illustrative examples are presented.

  6. Survival of ovarian cancer patients in Denmark

    DEFF Research Database (Denmark)

    Edwards, Hellen McKinnon; Noer, Mette Calundann; Sperling, Cecilie Dyg

    2016-01-01

    linked via the patients' personal identification number and the analyses included data on cancer stage, age, survival, surgery status and comorbidity. The computed outcome measures were age-adjusted mortality rates and age-adjusted overall and relative survival rates for one and five years. RESULTS: We......BACKGROUND: Ovarian cancer has a high mortality rate, especially in Denmark where mortality rates have been reported higher than in adjacent countries with similar demographics. This study therefore examined recent survival and mortality among Danish ovarian cancer patients over an 18-year study...... period. METHODS: This nationwide registry-based observational study used data from the Danish Gynecology Cancer Database, Danish Pathology Registry, and Danish National Patient Registry. All patients with ovarian cancer diagnosed between 1995 and 2012 were included in the study. The data sources were...

  7. Analysis of survival data from telemetry projects

    Science.gov (United States)

    Bunck, C.M.; Winterstein, S.R.; Pollock, K.H.

    1985-01-01

    Telemetry techniques can be used to study the survival rates of animal populations and are particularly suitable for species or settings for which band recovery models are not. Statistical methods for estimating survival rates and parameters of survival distributions from observations of radio-tagged animals will be described. These methods have been applied to medical and engineering studies and to the study of nest success. Estimates and tests based on discrete models, originally introduced by Mayfield, and on continuous models, both parametric and nonparametric, will be described. Generalizations, including staggered entry of subjects into the study and identification of mortality factors will be considered. Additional discussion topics will include sample size considerations, relocation frequency for subjects, and use of covariates.

  8. Panspermia Survival Scenarios for Organisms that Survive Typical Hypervelocity Solar System Impact Events.

    Science.gov (United States)

    Pasini, D.

    2014-04-01

    Previous experimental studies have demonstrated the survivability of living cells during hypervelocity impact events, testing the panspermia and litho-panspermia hypotheses [1]. It has been demonstrated by the authors that Nannochloropsis Oculata Phytoplankton, a eukaryotic photosynthesizing autotroph found in the 'euphotic zone' (sunlit surface layers of oceans [2]), survive impacts up to 6.93 km s-1 (approx. shock pressure 40 GPa) [3, 4]. Also shown to survive impacts up to 5.49 km s-1 is the tardigrade species Hypsibius dujardini (a complex micro-animal consisting of 40,000 cells) [5, 6]. It has also been shown that they can survive sustained pressures up to 600 MPa using a water filled pressure capsule [7]. Additionally bacteria can survive impacts up to 5.4 km s-1 (~30 GPa) - albeit with a low probability of survival [1], and the survivability of yeast spores in impacts up to 7.4 km s-1 (~30 GPa) has also recently been demonstrated [8]. Other groups have also reported that the lichen Xanthoria elegans is able to survive shocks in similar pressure ranges (~40 GPa) [9]. Here we present various simulated impact regimes to show which scenarios are condusive to the panspermia hypothesis of the natural transfer of life (via an icy body) through space to an extraterrestrial environment.

  9. Survival in common cancers defined by risk and survival of family members

    Directory of Open Access Journals (Sweden)

    Jianguang Ji

    2011-10-01

    Full Text Available Studies on survival between familial and sporadic cancers have been inconclusive and only recent data on a limited number of cancers are available on the concordance of survival between family members. In this review, we address these questions by evaluating the published and unpublished data from the nation-wide Swedish Family-Cancer Database and a total of 13 cancer sites were assessed. Using sporadic cancer as reference, HRs were close to 1.0 for most of the familial cancers in both the offspring and parental generations, which suggested that survival in patients with familial and sporadic cancers was equal, with an exception for ovarian cancer with a worse prognosis. Compared to offspring whose parents had a poor survival, those with a good parental survival had a decreased risk of death for most cancers and HR was significantly decreased for cancers in the breast, prostate, bladder, and kidney. For colorectal and nervous system cancers, favorable survival between the generations showed a borderline significance. These data are consistent in showing that both good and poor survival in certain cancers aggregate in families. Genetic factors are likely to contribute to the results. These observations call for intensified efforts to consider heritability in survival as one mechanism regulating prognosis in cancer patients.

  10. Acute traumatic coagulopathy decreased actual survival rate when compared with predicted survival rate in severe trauma.

    Science.gov (United States)

    Kim, Su Jin; Lee, Sung Woo; Han, Gap Su; Moon, Sung Woo; Choi, Sung Hyuck; Hong, Yun Sik

    2012-11-01

    To determine whether acute traumatic coagulopathy (ATC) should be combined with the trauma and injury severity score (TRISS) to predict outcome in severe trauma patients and investigate effects of the change in coagulation state during early resuscitation on the actual survival rate. This was a retrospective study. Significant variables that affected 28-day mortality were analysed using multivariate logistic regression. Study patients were classified into three groups: no coagulopathy, mild coagulopathy or severe coagulopathy. Concordance between actual and predicted survival rates were compared for each group. The predicted survival rate was calculated using the TRISS method. The study also determined whether changes in the coagulation state during inhospital resuscitation affected the relationship between actual and predicted survival in patients who had rechecked coagulation profile within 12 h after presentation. Data from a total of 336 patients were analysed. At presentation, 20.8% of the study patients had mild coagulopathy, whereas 7.7% had severe coagulopathy. Age, injury severity score, revised trauma score and presence of ATC at presentation were independently associated with 28-day mortality. Actual survival was significantly lower than predicted survival in the mild and severe coagulopathy groups. Aggravation of coagulation state from normal or mild to severe coagulopathy or persistent severe coagulopathy during inhospital resuscitation mainly contributed to the discrepancy between actual and predicted survival. ATC decreased actual survival more than expected. ATC should be combined with TRISS to predict trauma outcome in severely injured patients. Improvement in coagulopathy during resuscitation may reduce the incidence of preventable death after trauma.

  11. Changing Pattern in Malignant Mesothelioma Survival

    Directory of Open Access Journals (Sweden)

    Jennifer Faig

    2015-02-01

    Full Text Available Survival for mesothelioma has been shown to be poor, with marginal improvement over time. Recent advances in the understanding of pathophysiology and treatment of mesothelioma may impact therapy to improve survival that may not be evident from available clinical trials that are often small and not randomized. Therapies may affect survival differently based on mesothelioma location (pleural vs peritoneal. Data are conflicting regarding the effect of asbestos exposure on mesothelioma location. OBJECTIVES: We examined survival in a large cohort of mesothelioma subjects analyzed by tumor location and presence and mode of asbestos exposure. METHODS: Data were analyzed from cases (n = 380 diagnosed with mesothelioma from 1992 to 2012. Cases were either drawn from treatment referrals, independent medical evaluation for medical legal purposes, or volunteers who were diagnosed with mesothelioma. Subjects completed an occupational medical questionnaire, personal interview with the examining physician, and physician review of the medical record. RESULTS: This study reports better survival for mesothelioma than historical reports. Survival for peritoneal mesothelioma was longer than that for pleural mesothelioma (hazard ratio = 0.36, 95% confidence interval = 0.24-0.54, P < .001 after adjusting for gender and age at diagnosis. Non-occupational cases were more likely to be 1 diagnosed with peritoneal mesothelioma, 2 female, 3 exposed, and 4 diagnosed at a younger age and to have a 5 shorter latency compared to occupational cases (P < .001. CONCLUSION: Peritoneal mesothelioma was more likely associated with non-occupational exposure, thus emphasizing the importance of exposure history in enhancing early diagnosis and treatment impact.

  12. Making relative survival analysis relatively easy.

    Science.gov (United States)

    Pohar, Maja; Stare, Janez

    2007-12-01

    In survival analysis we are interested in time from the beginning of an observation until certain event (death, relapse, etc.). We assume that the final event is well defined, so that we are never in doubt whether the final event has occurred or not. In practice this is not always true. If we are interested in cause-specific deaths, then it may sometimes be difficult or even impossible to establish the cause of death, or there may be different causes of death, making it impossible to assign death to just one cause. Suicides of terminal cancer patients are a typical example. In such cases, standard survival techniques cannot be used for estimation of mortality due to a certain cause. The cure to the problem are relative survival techniques which compare the survival experience in a study cohort to the one expected should they follow the background population mortality rates. This enables the estimation of the proportion of deaths due to a certain cause. In this paper, we briefly review some of the techniques to model relative survival, and outline a new fitting method for the additive model, which solves the problem of dependency of the parameter estimation on the assumption about the baseline excess hazard. We then direct the reader's attention to our R package relsurv that provides functions for easy and flexible fitting of all the commonly used relative survival regression models. The basic features of the package have been described in detail elsewhere, but here we additionally explain the usage of the new fitting method and the interface for using population mortality data freely available on the Internet. The combination of the package and the data sets provides a powerful informational tool in the hands of a skilled statistician/informatician.

  13. Model selection criterion in survival analysis

    Science.gov (United States)

    Karabey, Uǧur; Tutkun, Nihal Ata

    2017-07-01

    Survival analysis deals with time until occurrence of an event of interest such as death, recurrence of an illness, the failure of an equipment or divorce. There are various survival models with semi-parametric or parametric approaches used in medical, natural or social sciences. The decision on the most appropriate model for the data is an important point of the analysis. In literature Akaike information criteria or Bayesian information criteria are used to select among nested models. In this study,the behavior of these information criterion is discussed for a real data set.

  14. Evaluating survival model performance: a graphical approach.

    Science.gov (United States)

    Mandel, M; Galai, N; Simchen, E

    2005-06-30

    In the last decade, many statistics have been suggested to evaluate the performance of survival models. These statistics evaluate the overall performance of a model ignoring possible variability in performance over time. Using an extension of measures used in binary regression, we propose a graphical method to depict the performance of a survival model over time. The method provides estimates of performance at specific time points and can be used as an informal test for detecting time varying effects of covariates in the Cox model framework. The method is illustrated on real and simulated data using Cox proportional hazard model and rank statistics. Copyright 2005 John Wiley & Sons, Ltd.

  15. A stochastic evolutionary model for survival dynamics

    Science.gov (United States)

    Fenner, Trevor; Levene, Mark; Loizou, George

    2014-09-01

    The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in different contexts. Here we propose a generative model to capture the essential dynamics of survival analysis, traditionally employed in clinical trials and reliability analysis in engineering. In our model, the only implicit assumption made is that the longer an actor has been in the system, the more likely it is to have failed. We derive a power-law distribution for the process and provide preliminary empirical evidence for the validity of the model from two well-known survival analysis data sets.

  16. Body mass index and breast cancer survival

    DEFF Research Database (Denmark)

    Guo, Qi; Burgess, Stephen; Turman, Constance

    2017-01-01

    Background: There is increasing evidence that elevated body mass index (BMI) is associated with reduced survival for women with breast cancer. However, the underlying reasons remain unclear. We conducted a Mendelian randomization analysis to investigate a possible causal role of BMI in survival...... from breast cancer. Methods: We used individual-level data from six large breast cancer case-cohorts including a total of 36 210 individuals (2475 events) of European ancestry. We created a BMI genetic risk score (GRS) based on genotypes at 94 known BMI-associated genetic variants. Association between...

  17. Improved survival after rectal cancer in Denmark

    DEFF Research Database (Denmark)

    Bülow, S; Harling, H; Iversen, L H

    2010-01-01

    treated from 1994 to 2006. Method The study was based on the National Rectal Cancer Registry and the National Colorectal Cancer Database, supplemented with data from the Central Population Registry. The analysis included actuarial overall and relative survival. Results A total of 10 632 patients were......Objective In 1995, an analysis showed an inferior prognosis after rectal cancer in Denmark compared with the other Scandinavian countries. The Danish Colorectal Cancer Group (DCCG) was established with the aim of improving the prognosis, and in this study we present a survival analysis of patients...

  18. Graphics and statistics for cardiology: survival analysis.

    Science.gov (United States)

    May, Susanne; McKnight, Barbara

    2017-03-01

    Reports of data in the medical literature frequently lack information needed to assess the validity and generalisability of study results. Some recommendations and standards for reporting have been developed over the last two decades, but few are available specifically for survival data. We provide recommendations for tabular and graphical representations of survival data. We argue that data and analytic software should be made available to promote reproducible research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. Multiple neoplasms, single primaries, and patient survival

    Directory of Open Access Journals (Sweden)

    Amer MH

    2014-03-01

    Full Text Available Magid H Amer Department of Medicine, St Rita's Medical Center, Lima, OH, USA Background: Multiple primary neoplasms in surviving cancer patients are relatively common, with an increasing incidence. Their impact on survival has not been clearly defined. Methods: This was a retrospective review of clinical data for all consecutive patients with histologically confirmed cancer, with emphasis on single versus multiple primary neoplasms. Second primaries discovered at the workup of the index (first primary were termed simultaneous, if discovered within 6 months of the index primary were called synchronous, and if discovered after 6 months were termed metachronous. Results: Between 2005 and 2012, of 1,873 cancer patients, 322 developed second malignancies; these included two primaries (n=284, and three or more primaries (n=38. Forty-seven patients had synchronous primaries and 275 had metachronous primaries. Patients with multiple primaries were predominantly of Caucasian ancestry (91.0%, with a tendency to develop thrombosis (20.2%, had a strong family history of similar cancer (22.3%, and usually presented with earlier stage 0 through stage II disease (78.9%. When compared with 1,551 patients with a single primary, these figures were 8.9%, 15.6%, 18.3%, and 50.9%, respectively (P≤0.001. Five-year survival rates were higher for metachronous cancers (95% than for synchronous primaries (59% and single primaries (59%. The worst survival rate was for simultaneous concomitant multiple primaries, being a median of 1.9 years. The best survival was for patients with three or more primaries (median 10.9 years and was similar to the expected survival for the age-matched and sex-matched general population (P=0.06991. Conclusion: Patients with multiple primaries are usually of Caucasian ancestry, have less aggressive malignancies, present at earlier stages, frequently have a strong family history of similar cancer, and their cancers tend to have indolent

  20. Survival during the Breeding Season: Nest Stage, Parental Sex, and Season Advancement Affect Reed Warbler Survival.

    Directory of Open Access Journals (Sweden)

    Kaja Wierucka

    Full Text Available Avian annual survival has received much attention, yet little is known about seasonal patterns in survival, especially of migratory passerines. In order to evaluate survival rates and timing of mortality within the breeding season of adult reed warblers (Acrocephalus scirpaceus, mark-recapture data were collected in southwest Poland, between 2006 and 2012. A total of 612 individuals (304 females and 308 males were monitored throughout the entire breeding season, and their capture-recapture histories were used to model survival rates. Males showed higher survival during the breeding season (0.985, 95% CI: 0.941-0.996 than females (0.869, 95% CI: 0.727-0.937. Survival rates of females declined with the progression of the breeding season (from May to August, while males showed constant survival during this period. We also found a clear pattern within the female (but not male nesting cycle: survival was significantly lower during the laying, incubation, and nestling periods (0.934, 95% CI: 0.898-0.958, when birds spent much time on the nest, compared to the nest building and fledgling periods (1.000, 95% CI: 1.00-1.000, when we did not record any female mortality. These data (coupled with some direct evidence, like bird corpses or blood remains found next to/on the nest may suggest that the main cause of adult mortality was on-nest predation. The calculated survival rates for both sexes during the breeding season were high compared to annual rates reported for this species, suggesting that a majority of mortality occurs at other times of the year, during migration or wintering. These results have implications for understanding survival variation within the reproductive period as well as general trends of avian mortality.

  1. 46 CFR 117.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 117.130 Section 117.130... AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 117.130 Stowage of survival craft. (a) Each survival craft must be: (1) Secured to the vessel by a painter with a float-free link permanently...

  2. 46 CFR 133.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 133.130 Section 133.130... SYSTEMS Requirements for All OSVs § 133.130 Stowage of survival craft. (a) General. Each survival craft must be stowed as follows: (1) Each survival craft must be as close to the accommodation and service...

  3. 46 CFR 108.530 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 108.530 Section 108.530... AND EQUIPMENT Lifesaving Equipment § 108.530 Stowage of survival craft. (a) General. Each survival... follows: (1) Each survival craft must be stowed as close to the accommodation and service spaces as...

  4. 46 CFR 180.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 180.130 Section 180.130... TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 180.130 Stowage of survival craft. (a) Each survival craft must be: (1) Secured to the vessel by a painter with a...

  5. 46 CFR 28.310 - Launching of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Launching of survival craft. 28.310 Section 28.310... Operate With More Than 16 Individuals on Board § 28.310 Launching of survival craft. A gate or other... each survival craft which weighs more than 110 pounds (489 Newtons), to allow the survival craft to be...

  6. Survival and reproduction of radio-marked adult spotted owls.

    Science.gov (United States)

    C.C. Foster; E.D. Forsman; E.C. Meslow; G.S. Miller; J.A. Reid; F.F. Wagner; A.B. Carey; J.B. Lint

    1992-01-01

    We compared survival, reproduction, and body mass of radio-marked and non radio-marked spotted owls (Strix occidentalis) to determine if backpack radios influenced reproduction or survival. In most study areas and years, there were no differences (P > 0.05) in survival of males and females or in survival of radio-marked versus banded owls. There...

  7. Surviving 1000 centuries can we do it?

    CERN Document Server

    Bonnet, Roger-Maurice

    2010-01-01

    This full color book provides a quantitative view of our civilization over the next 100,000 years. The authors present the dangers and stress the importance of taking decisions in the 21st century to ensure the long-term survival of people on Earth.

  8. A Child Survival and Development Revolution?

    Science.gov (United States)

    Halpern, Robert

    1986-01-01

    Addresses the problems of child survival and development in developing countries by discussing the biomedical causes and the concomitant social determinants of high infant mortality rates. Describes four intervention strategies recommended by UNICEF: growth monitoring, oral rehydration therapy, breast feeding, and immunization. (HOD)

  9. From Survival to Sustainability : Nurturing Adaptive Livelihood ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2005-10-08

    From Survival to Sustainability : Nurturing Adaptive Livelihood Strategies in Pakistan. On October 8, 2005, an earthquake destroyed 90% of the town of tehsil Balakot, Mansehra district, Pakistan. According to the Earthquake Reconstruction and Rehabilitation Authority (ERRA) the earthquake left a total of 24 511 dead and ...

  10. Advanced wing design survivability testing and results

    Science.gov (United States)

    Bruno, J.; Tobias, M.

    1992-01-01

    Composite wings on current operational aircraft are conservatively designed to account for stress/strain concentrations, and to assure specified damage tolerance. The technology that can lead to improved composite wing structures and associated structural efficiency is to increase design ultimate strain levels beyond their current limit of 3500 to 4000 micro-in/in to 6000 micro-in/in without sacrificing structural integrity, durability, damage tolerance, or survivability. Grumman, under the sponsorship of the Naval Air Development Center (NADC), has developed a high-strain composite wing design for a subsonic aircraft wing using novel and innovative design concepts and manufacturing methods, while maintaining a state-of-the-art fiber/resin system. The current advanced wing design effort addressed a tactical subsonic aircraft wing using previously developed, high-strain wing design concepts in conjunction with newer/emerging fiber and polymer matrix composite (PMC) materials to achieve the same goals, while reducing complexity. Two categories of advanced PMC materials were evaluated: toughened thermosets; and engineered thermoplastics. Advanced PMC materials offer the technological opportunity to take maximum advantage of improved material properties, physical characteristics, and tailorability to increase performance and survivability over current composite structure. Damage tolerance and survivability to various threats, in addition to structural integrity and durability, were key technical issues addressed during this study, and evaluated through test. This paper focuses on the live-fire testing, and the results performed to experimentally evaluate the survivability of the advanced wing design.

  11. Revisiting the survival mnemonic effect in children.

    Science.gov (United States)

    Pand eirada, Josefa N S; Pires, Luísa; Soares, Sandra C

    2014-04-29

    The survival processing paradigm is designed to explore the adaptive nature of memory functioning. The mnemonic advantage of processing information in fitness-relevant contexts, as has been demonstrated using this paradigm, is now well established, particularly in young adults; this phenomenon is often referred to as the "survival processing effect." In the current experiment, we revisited the investigation of this effect in children and tested it in a new cultural group, using a procedure that differs from the existing studies with children. A group of 40 Portuguese children rated the relevance of unrelated words to a survival and a new moving scenario. This encoding task was followed by a surprise free-recall task. Akin to what is typically found, survival processing produced better memory performance than the control condition (moving). These data put on firmer ground the idea that a mnemonic tuning to fitness-relevant encodings is present early in development. The theoretical importance of this result to the adaptive memory literature is discussed, as well as potential practical implications of this kind of approach to the study of memory in children.

  12. Revisiting the Survival Mnemonic Effect in Children

    Directory of Open Access Journals (Sweden)

    Josefa N. S. Pand Eirada

    2014-04-01

    Full Text Available The survival processing paradigm is designed to explore the adaptive nature of memory functioning. The mnemonic advantage of processing information in fitness-relevant contexts, as has been demonstrated using this paradigm, is now well established, particularly in young adults; this phenomenon is often referred to as the “survival processing effect.” In the current experiment, we revisited the investigation of this effect in children and tested it in a new cultural group, using a procedure that differs from the existing studies with children. A group of 40 Portuguese children rated the relevance of unrelated words to a survival and a new moving scenario. This encoding task was followed by a surprise free-recall task. Akin to what is typically found, survival processing produced better memory performance than the control condition (moving. These data put on firmer ground the idea that a mnemonic tuning to fitness-relevant encodings is present early in development. The theoretical importance of this result to the adaptive memory literature is discussed, as well as potential practical implications of this kind of approach to the study of memory in children.

  13. MANAGEMENT AND SURVIVAL IN ADVANCED PROSTATE ...

    African Journals Online (AJOL)

    hi-tech

    2000-05-05

    May 5, 2000 ... Objective: To evaluate the management and survival of patients with advanced prostate cancer in this locality. Design: A prospective case study. Setting: Kenyatta National Referral Hospital and the Nairobi and Mater Hospitals. Patients: Fifty nine patients with advanced cancer of prostate (extra prostatic ...

  14. Survival of emerald ash borer in chips

    Science.gov (United States)

    Deborah G. McCullough; Therese M. Poland; David L. Cappaert

    2005-01-01

    The ability of emerald ash borer (EAB), Agrilus planipennis Fairmaire, to survive following chipping or grinding of infested ash trees remains a critical question for regulatory officials. In October 2002, we felled eight infested ash trees and sampled sections of the trunk and large branches from each tree to estimate EAB density.

  15. Association between consanguinity and survival of marriages

    Directory of Open Access Journals (Sweden)

    Mostafa Saadat

    2015-01-01

    Conclusion: The present findings indicate that consanguinity has some protective role(s against divorce and also survival of marriages increased among consanguineous marriages. Considering that divorce rate is affected by several factors, replication of present findings in other populations is recommended.

  16. MECHANICAL TRANSMISSION AND SURVIVAL OF BACTERIAL ...

    African Journals Online (AJOL)

    jen

    Key Words: Bacterial wilt, enset, survival, transmission, Xanthomonas campestris pv. musacearum. RÉSUMÉ. La transmission .... than young plants. A 100% disease incidence was recorded at 60 days after inoculation on plants inoculated at 6 months after transplanting. Plants inoculated at. 6 months after transplanting had ...

  17. Burned Oaks: Which Ones Will Survive?

    OpenAIRE

    McCreary, Doug; Nader, Glenn

    2011-01-01

    Wildfire in an oak woodland can kill some trees outright and leave others with burn damage that may or may not eventually kill them, too. Here is a quick method for assessing the extent of burn damage and the likelihood that an affected tree will survive.

  18. Modeling survival data extending the cox model

    CERN Document Server

    Therneau, Terry M

    2000-01-01

    Extending the Cox Model is aimed at researchers, practitioners, and graduate students who have some exposure to traditional methods of survival analysis The emphasis is on semiparametric methods based on the proportional hazards model The inclusion of examples with SAS and S-PLUS code will make the book accessible to most working statisticians

  19. Foreign acquisition, plant survival, and employment growth

    DEFF Research Database (Denmark)

    Bandick, Roger; Görg, Holger

    2010-01-01

    This paper analyzes the effect of foreign acquisition on survival and employment growth of targets using data on Swedish manufacturing plants.We separate targeted plants into those within Swedish MNEs, Swedish exporting non-MNEs, and purely domestic firms. The results, controlling for possible...... acquisitions. We find robust positive employment growth effects only for exporters and only if the takeover is vertical....

  20. Growth response and survival of Heterobranchus longifilis ...

    African Journals Online (AJOL)

    In an effort to utilize feed efficiently, promote growth, increase survival and reduce labour costs associated with feeding, Heterobranchus longifilis ingerlings were placed on one of four feeding frequencies; once/day, twice/day; once every other day, and twice every other day for 56 days. They were fed with a commercial ...

  1. Surviving the War--And the Peace

    Science.gov (United States)

    Thompson, Doug

    2012-01-01

    This article presents the author's response to "Surviving the War: A College Counselor's Journal" by Philip Clinton. He argues that Clinton's engrossing account of the 1990-91 school year at Cairo American College (CAC) gives individuals wonderful insights into the unusual challenges occasionally encountered by an international…

  2. Variceal recurrence, rebleeding and survival after injection ...

    African Journals Online (AJOL)

    Variceal recurrence, rebleeding and survival after injection sclerotherapy in 306 alcoholic cirrhotic patients with bleeding oesophageal varices: original. ... The 306 patients (239 men, 67 women; mean age 51.6, range 24-87 years) underwent 387 emergency and 1067 elective injection treatments with 5% ethanolamine ...

  3. Neyman, Markov processes and survival analysis.

    Science.gov (United States)

    Yang, Grace

    2013-07-01

    J. Neyman used stochastic processes extensively in his applied work. One example is the Fix and Neyman (F-N) competing risks model (1951) that uses finite homogeneous Markov processes to analyse clinical trials with breast cancer patients. We revisit the F-N model, and compare it with the Kaplan-Meier (K-M) formulation for right censored data. The comparison offers a way to generalize the K-M formulation to include risks of recovery and relapses in the calculation of a patient's survival probability. The generalization is to extend the F-N model to a nonhomogeneous Markov process. Closed-form solutions of the survival probability are available in special cases of the nonhomogeneous processes, like the popular multiple decrement model (including the K-M model) and Chiang's staging model, but these models do not consider recovery and relapses while the F-N model does. An analysis of sero-epidemiology current status data with recurrent events is illustrated. Fix and Neyman used Neyman's RBAN (regular best asymptotic normal) estimates for the risks, and provided a numerical example showing the importance of considering both the survival probability and the length of time of a patient living a normal life in the evaluation of clinical trials. The said extension would result in a complicated model and it is unlikely to find analytical closed-form solutions for survival analysis. With ever increasing computing power, numerical methods offer a viable way of investigating the problem.

  4. Weight, physical activity and breast cancer survival.

    Science.gov (United States)

    McTiernan, Anne

    2018-02-26

    Weight, weight change and physical activity may affect prognosis among women who are diagnosed with breast cancer. Observational studies show associations between overweight/obesity and weight gain with several measures of reduced prognosis in women with breast cancer, and some suggestions of lower survival in women who are underweight or who experience unexplained weight loss after diagnosis. Observational studies have also shown an association between higher levels of physical activity and reduced breast cancer-specific and all-cause mortality, although a dose-response relationship has not been established. The effects of purposive dietary weight loss and increase in physical activity on survival or recurrence in breast cancer are not yet established, and randomised controlled trials are needed for definitive data. This paper presents the epidemiologic evidence on weight status, weight change, and physical activity and breast cancer survival; suggests potential mediating mechanisms; summarises evidence on weight loss interventions in breast cancer survivors; describes ongoing randomised clinical trials designed to test the effects of weight loss or physical activity on breast cancer survival; and provides information on available guidelines on weight and physical activity for cancer survivors.

  5. Longevity and Patau syndrome: what determines survival?

    Science.gov (United States)

    Peroos, Sherina; Forsythe, Elizabeth; Pugh, Jennifer Harriet; Arthur-Farraj, Peter; Hodes, Deborah

    2012-12-06

    The authors report of an 8-year-old girl with non-mosaic Patau syndrome. The median life expectancy of Patau syndrome is 7-10 days, and 90% die in the first year of life. Survival is often attributed to mosaicism and the severity of associated malformations. We delineate the developing phenotype and review the literature discussing potential contributory factors to longevity.

  6. Antibiotic Susceptibility Profile and Survival of Bifidobacterium ...

    African Journals Online (AJOL)

    Bifidobacteria are categorized as health-promoting microorganisms (probiotics) in the gastrointestinal tracts of humans and animals. Antibiotic susceptibility is a key criterion for probiotic agent selection. Good survival of probiotics during storage at selected storage temperature(s) is highly desirable. Bifidobacteria isolated ...

  7. Comparing survival curves using rank tests

    NARCIS (Netherlands)

    Albers, Willem/Wim

    1990-01-01

    Survival times of patients can be compared using rank tests in various experimental setups, including the two-sample case and the case of paired data. Attention is focussed on two frequently occurring complications in medical applications: censoring and tail alternatives. A review is given of the

  8. Male microchimerism and survival among women

    DEFF Research Database (Denmark)

    Kamper-Jørgensen, Mads; Hjalgrim, Henrik; Andersen, Anne-Marie Nybo

    2014-01-01

    During pregnancy, woman and fetus exchange small quantities of cells, and their persistence at later times is termed microchimerism. Microchimerism is known to substantially impact on women's later health. This study examined the survival of women according to male microchimerism status....

  9. Survival by Dialysis Modality-Who Cares?

    Science.gov (United States)

    Lee, Martin B; Bargman, Joanne M

    2016-06-06

    In light of the recent emphasis on patient-centered outcomes and quality of life for patients with kidney disease, we contend that the nephrology community should no longer fund, perform, or publish studies that compare survival by dialysis modality. These studies have become redundant; they are methodologically limited, unhelpful in practice, and therefore a waste of resources. More than two decades of these publications show similar survival between patients undergoing peritoneal dialysis and those receiving thrice-weekly conventional hemodialysis, with differences only for specific subgroups. In clinical practice, modality choice should be individualized with the aim of maximizing quality of life, patient-reported outcomes, and achieving patient-centered goals. Expected survival is often irrelevant to modality choice. Even for the younger and fitter home hemodialysis population, quality of life, not just duration of survival, is a major priority. On the other hand, increasing evidence suggests that patients with ESRD continue to experience poor quality of life because of high symptom burden, unsolved clinical problems, and unmet needs. Patients care more about how they will live instead of how long. It is our responsibility to align our research with their needs. Only by doing so can we meet the challenges of ESRD patient care in the coming decades. Copyright © 2016 by the American Society of Nephrology.

  10. Le survivant sans le syndrome Schreber

    Directory of Open Access Journals (Sweden)

    Richard Figuier

    2006-09-01

    Full Text Available On a pensé la catastrophe, mais a-t-on suffisamment pensé la survivance et la figure du survivant ? Ce n'est pas un hasard si celle-ci est au centre de Masse et puissance, oeuvre dans laquelle Canetti interroge la « mauvaise » survivance responsable de la poursuite de la logique de guerre. Mais où trouver la « bonne » ? Revenir de la catastrophe ne suffit pas pour être un « survivant authentique », selon l'expression de Kafka. Il faut avoir dépassé, avec Primo Levi et Robert Antelme, l'opposition de la vie comme croissance continue et de la mort comme son horrible contraire, par le don, dans la pauvreté solidaire, de cette vie retrouvée.Hemos reflexionado acerca de la catástrofe, pero ¿hemos meditado lo suficiente sobre la supervivencia y el superviviente? No es una coincidencia si el superviviente es el tema principal de Masse et puissance, obra en la cual Canetti analiza la «mala» supervivencia responsable de la persistencia de la lógica de guerra ¿Dónde sin embargo podemos encontrar la «buena» supervivencia? Superar la catástrofe no es suficiente para ser un «auténtico superviviente», según Kafka. Es fundamental ir más allá, con Primo Levi y Robert Antelme, de la oposición entre la vida, como crecimiento continuo, y la muerte, como su espantoso contrario, mediante la donación de forma solidaria de esta vida reencontrada.Disaster is the theme of many studies, but what about survival and of the figure of the survivor? This issue is central in Mass and power, work in which Canetti questions the “bad” survival, responsible for the continuation of the logic of war. But is there any “good” survival? Coming back from the catastrophe is not enough to be an “authentic survivor”, according to Kafka’s expression. To achieve this, it is necessary to have exceeded, with PrimoLevi and Robert Antelme, the opposition of life as a continuous growth and of death as its horrible opposite, by the gift, in a

  11. Treatment with finasteride and prostate cancer survival.

    Science.gov (United States)

    Kjellman, Anders; Friis, Søren; Granath, Fredrik; Gustafsson, Ove; Sørensen, Henrik Toft; Akre, Olof

    2013-08-01

    This study compared survival after diagnosis of prostate cancer (PC) in men previously treated with finasteride, in men previously treated with α-adrenoceptor antagonists, in men treated with both, and in men who had received neither type of medication. In total, 3791 men diagnosed with PC in northern Denmark were identified. The region's prescription database was used to identify all men prescribed finasteride and α-adrenoceptor antagonists and those who had received neither medication during the period 1989-2001. Among men with a diagnosis of PC, overall survival and disease-specific survival were assessed after diagnosis using Cox proportional hazards regression. The risk of being diagnosed with non-localized PC was estimated using conditional logistic regression. The adjusted hazard ratio (HR) for PC death and overall death after treatment with finasteride was 0.93 [95% confidence interval (CI) 0.76-1.14] and 0.92 (95% CI 0.77-1.10), respectively. Treatment with α-adrenoceptor antagonists was associated with a reduced risk of PC death and overall death (HR 0.78, 95% CI 0.67-0.90, and 0.82, 95% CI 0.73-0.93, respectively. The risk of being diagnosed with non-localized PC was increased for men taking finasteride (odds ratio 1.14, 95% CI 1.01-1.29) per 100 defined daily doses. Treatment with finasteride prior to a diagnosis of PC did not affect PC-specific survival, but increased the risk of being diagnosed with non-localized disease. Treatment with α-adrenoceptor antagonists was associated with better cause-specific survival and lower risk of non-localized disease.

  12. Survival analysis of patients on maintenance hemodialysis

    Directory of Open Access Journals (Sweden)

    A Chandrashekar

    2014-01-01

    Full Text Available Despite the continuous improvement of dialysis technology and pharmacological treatment, mortality rates for dialysis patients are still high. A 2-year prospective study was conducted at a tertiary care hospital to determine the factors influencing survival among patients on maintenance hemodialysis. 96 patients with end-stage renal disease surviving more than 3 months on hemodialysis (8-12 h/week were studied. Follow-up was censored at the time of death or at the end of 2-year study period, whichever occurred first. Of the 96 patients studied (mean age 49.74 ± 14.55 years, 75% male and 44.7% diabetics, 19 died with an estimated mortality rate of 19.8%. On an age-adjusted multivariate analysis, female gender and hypokalemia independently predicted mortality. In Cox analyses, patient survival was associated with delivered dialysis dose (single pool Kt/V, hazard ratio [HR] =0.01, P = 0.016, frequency of hemodialysis (HR = 3.81, P = 0.05 and serum albumin (HR = 0.24, P = 0.005. There was no significant difference between diabetes and non-diabetes in relation to death (Relative Risk = 1.109; 95% CI = 0.49-2.48, P = 0.803. This study revealed that mortality among hemodialysis patients remained high, mostly due to sepsis and ischemic heart disease. Patient survival was better with higher dialysis dose, increased frequency of dialysis and adequate serum albumin level. Efforts at minimizing infectious complications, preventing cardiovascular events and improving nutrition should increase survival among hemodialysis patients.

  13. Survival Prognosis in Very Old Adults

    Science.gov (United States)

    Thinggaard, Mikael; McGue, Matt; Jeune, Bernard; Osler, Merete; Vaupel, James W.; Christensen, Kaare

    2016-01-01

    OBJECTIVES To determine whether simple functional indicators are predictors of survival prognosis in very old adults. DESIGN In-person survey conducted over a 3-month period in 1998; assessment of survival over a 15-year follow-up period. SETTING Denmark. PARTICIPANTS All 3,600 Danes born in 1905 and living in Denmark in 1998, were invited to participate regardless of residence and health; 2,262 (63%) participated in the survey: 1,814 (80.2%) in person and 448 (19.8%) through a proxy. MEASUREMENTS Socioeconomic factors, medications and diseases, activities of daily living, physical performance, cognition, depression symptomatology, self-rated health, and all-cause mortality, evaluated as average remaining lifespan and chance of surviving to 100 years. RESULTS Men aged 92 to 93 had an overall 6.0% chance of surviving to 100 years, whereas the chance for women was 11.4%. Being able to rise without use of hands increased the chance for men to 11.2% (95% confidence interval (CI) = 7.7–14.7) and for women to 22.0% (95% CI = 18.9–25.1). When combining this with a Mini-Mental State Examination (MMSE) scores from 28 to 30, the chances were 21.7% (95% CI = 11.5–31.9) for men and 34.2% (95% CI = 24.8–43.5) for women. CONCLUSION Chair stand score combined with MMSE score is a quick and easy way to estimate overall chance of survival in very old adults, which is particularly relevant when treatment with potential side effects for nonacute diseases is considered. J Am Geriatr Soc 64:81–88, 2016. PMID:26782855

  14. Attributing death to cancer: cause-specific survival estimation.

    Directory of Open Access Journals (Sweden)

    Mathew A

    2002-10-01

    Full Text Available Cancer survival estimation is an important part of assessing the overall strength of cancer care in a region. Generally, the death of a patient is taken as the end point in estimation of overall survival. When calculating the overall survival, the cause of death is not taken into account. With increasing demand for better survival of cancer patients it is important for clinicians and researchers to know about survival statistics due to disease of interest, i.e. net survival. It is also important to choose the best method for estimating net survival. Increase in the use of computer programmes has made it possible to carry out statistical analysis without guidance from a bio-statistician. This is of prime importance in third- world countries as there are a few trained bio-statisticians to guide clinicians and researchers. The present communication describes current methods used to estimate net survival such as cause-specific survival and relative survival. The limitation of estimation of cause-specific survival particularly in India and the usefulness of relative survival are discussed. The various sources for estimating cancer survival are also discussed. As survival-estimates are to be projected on to the population at large, it becomes important to measure the variation of the estimates, and thus confidence intervals are used. Rothman′s confidence interval gives the most satisfactory result for survival estimate.

  15. Successful implementation of Helping Babies Survive and Helping Mothers Survive programs-An Utstein formula for newborn and maternal survival.

    Directory of Open Access Journals (Sweden)

    Hege L Ersdal

    Full Text Available Globally, the burden of deaths and illness is still unacceptably high at the day of birth. Annually, approximately 300.000 women die related to childbirth, 2.7 million babies die within their first month of life, and 2.6 million babies are stillborn. Many of these fatalities could be avoided by basic, but prompt care, if birth attendants around the world had the necessary skills and competencies to manage life-threatening complications around the time of birth. Thus, the innovative Helping Babies Survive (HBS and Helping Mothers Survive (HMS programs emerged to meet the need for more practical, low-cost, and low-tech simulation-based training. This paper provides users of HBS and HMS programs a 10-point list of key implementation steps to create sustained impact, leading to increased survival of mothers and babies. The list evolved through an Utstein consensus process, involving a broad spectrum of international experts within the field, and can be used as a means to guide processes in low-resourced countries. Successful implementation of HBS and HMS training programs require country-led commitment, readiness, and follow-up to create local accountability and ownership. Each country has to identify its own gaps and define realistic service delivery standards and patient outcome goals depending on available financial resources for dissemination and sustainment.

  16. [Problems and priorities in child survival].

    Science.gov (United States)

    Bobadilla, J L

    1988-01-01

    This work synthesizes the conclusions and recommendations of the 1985 International Workshop on Child Survival held in Teotihuacan, Mexico. Data are presented which document the extent of the problem of child survival in Latin America and the deficiencies of available data. Malnutrition, diseases preventable through vaccination, diarrheal diseases, acute respiratory infections, perinatal disorders, and shortcomings in quality of care are separately discussed following an assessment of their socioeconomic and cultural determining factors. Recent advances in the preventive component of primary health care programs are discussed. In Latin America, 900 of each 1000 live born babies survive to the 5th year of life compared to 980 in developed countries. Although the mortality rate of children under 5 in Latin America declined from 128 in 1950-55 to 63 in 1980-85, there are wide disparities between countries. Most countries of Latin America were classified as having high or very high infant and child mortality. There are serious differences in child survival between geographic regions and social groups of each country. The mortality decline in Costa Rica, Cuba, and Chile demonstrates that other countries could avoid a large proportion of deaths by ensuring that benefits of current programs have broader coverage. The severe economic crisis in Mexico and other countries threatens the progress already achieved in child survival. The recommendations of the conference are based on the premise that recent efforts to improve survival have been insufficient and a more rational use of the available resources and knowledge is required. In the area of health policy, priority should continue to be given to providing care for mothers and small children. Investments should be reoriented toward extending coverage of primary health care. The proportion of mothers attended during delivery by trained paramedical personnel or physicians should be increased, and family planning programs in

  17. Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves

    National Research Council Canada - National Science Library

    Guyot, Patricia; Ades, A E; Ouwens, Mario J N M; Welton, Nicky J

    2012-01-01

    .... In order to enhance the quality of secondary data analyses, we propose a method which derives from the published Kaplan Meier survival curves a close approximation to the original individual patient...

  18. Survival rates and predictors of survival among colorectal cancer patients in a Malaysian tertiary hospital.

    Science.gov (United States)

    Magaji, Bello Arkilla; Moy, Foong Ming; Roslani, April Camilla; Law, Chee Wei

    2017-05-18

    Colorectal cancer is the third most commonly diagnosed malignancy and the fourth leading cause of cancer-related death globally. It is the second most common cancer among both males and females in Malaysia. The economic burden of colorectal cancer is likely to increase over time owing to its current trend and aging population. Cancer survival analysis is an essential indicator for early detection and improvement in cancer treatment. However, there was a scarcity of studies concerning survival of colorectal cancer patients as well as its predictors. Therefore, we aimed to determine the 1-, 3- and 5-year survival rates, compare survival rates among ethnic groups and determine the predictors of survival among colorectal cancer patients. This was an ambidirectional cohort study conducted at the University Malaya Medical Centre (UMMC) in Kuala Lumpur, Malaysia. All Malaysian citizens or permanent residents with histologically confirmed diagnosis of colorectal cancer seen at UMMC from 1 January 2001 to 31 December 2010 were included in the study. Demographic and clinical characteristics were extracted from the medical records. Patients were followed-up until death or censored at the end of the study (31st December 2010). Censored patients' vital status (whether alive or dead) were cross checked with the National Registration Department. Survival analyses at 1-, 3- and 5-year intervals were performed using the Kaplan-Meier method. Log-rank test was used to compare the survival rates, while Cox proportional hazard regression analysis was carried out to determine the predictors of 5-year colorectal cancer survival. Among 1212 patients, the median survival for colorectal, colon and rectal cancers were 42.0, 42.0 and 41.0 months respectively; while the 1-, 3-, and 5-year relative survival rates ranged from 73.8 to 76.0%, 52.1 to 53.7% and 40.4 to 45.4% respectively. The Chinese patients had the lowest 5-year survival compared to Malay and Indian patients. Based on the 814

  19. Combining parametric, semi-parametric, and non-parametric survival models with stacked survival models.

    Science.gov (United States)

    Wey, Andrew; Connett, John; Rudser, Kyle

    2015-07-01

    For estimating conditional survival functions, non-parametric estimators can be preferred to parametric and semi-parametric estimators due to relaxed assumptions that enable robust estimation. Yet, even when misspecified, parametric and semi-parametric estimators can possess better operating characteristics in small sample sizes due to smaller variance than non-parametric estimators. Fundamentally, this is a bias-variance trade-off situation in that the sample size is not large enough to take advantage of the low bias of non-parametric estimation. Stacked survival models estimate an optimally weighted combination of models that can span parametric, semi-parametric, and non-parametric models by minimizing prediction error. An extensive simulation study demonstrates that stacked survival models consistently perform well across a wide range of scenarios by adaptively balancing the strengths and weaknesses of individual candidate survival models. In addition, stacked survival models perform as well as or better than the model selected through cross-validation. Finally, stacked survival models are applied to a well-known German breast cancer study. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. FS5 sun exposure survivability analysis

    Directory of Open Access Journals (Sweden)

    Ming-Ying Hsu

    2017-01-01

    Full Text Available During the Acquisition and Safe Hold (ASH mode, FORMOAT-5 (FS5 satellite attitude is not fully controlled. Direct sun exposure on the Remote Sensing Instrument (RSI satellite telescope sensor may occur. The sun exposure effect on RSI sensor performance is investigated to evaluate the instrument’s survivability in orbit. Both satellite spin speed and sun exposure duration are considered as the key parameters in this study. A simple radiometry technique is used to calculate the total sun radiance exposure to examine the RSI sensor integrity. Total sun irradiance on the sensor is computed by considering the spectral variation effect through the RSI’s five-band filter. Experiments that directly expose the sensor to the sun on the ground were performed with no obvious performance degradation found. Based on both the analysis and experiment results, it is concluded that the FS5 RSI sensor can survive direct sun exposure during the ASH mode.

  1. Socioeconomic position and survival after lung cancer

    DEFF Research Database (Denmark)

    Dalton, Susanne O.; Steding-Jessen, Marianne; Jakobsen, Erik

    2015-01-01

    BACKGROUND: To address social inequality in survival after lung cancer, it is important to consider how socioeconomic position (SEP) influences prognosis. We investigated whether SEP influenced receipt of first-line treatment and whether socioeconomic differences in survival could be explained...... by differences in stage, treatment and comorbidity. MATERIAL AND METHODS: In the Danish Lung Cancer Register, we identified 13 045 patients with lung cancer diagnosed in 2004-2010, with information on stage, histology, performance status and first-line treatment. We obtained age, gender, vital status, comorbid...... with stepwise inclusion of possible mediators. RESULTS: For both low- and high-stage lung cancer, adjusted ORs for first-line treatment were reduced in patients with short education and low income, although the OR for education did not reach statistical significance in men with high-stage disease. Patients...

  2. Survival Prognosis in Very Old Adults

    DEFF Research Database (Denmark)

    Thinggaard, Mikael; McGue, Matt; Jeune, Bernard

    2016-01-01

    to rise without use of hands increased the chance for men to 11.2% (95% confidence interval (CI)=7.7-14.7) and for women to 22.0% (95% CI=18.9-25.1). When combining this with a Mini-Mental State Examination (MMSE) scores from 28 to 30, the chances were 21.7% (95% CI=11.5-31.9) for men and 34.2% (95% CI=24...... performance, cognition, depression symptomatology, self-rated health, and all-cause mortality, evaluated as average remaining lifespan and chance of surviving to 100 years. RESULTS: Men aged 92 to 93 had an overall 6.0% chance of surviving to 100 years, whereas the chance for women was 11.4%. Being able...

  3. Implant survival after total elbow arthroplasty

    DEFF Research Database (Denmark)

    Plaschke, Hans Christian; Thillemann, Theis M; Brorson, Stig

    2014-01-01

    BACKGROUND: Total elbow arthroplasty (TEA) is an established treatment for late-stage arthritis of the elbow. Indications have expanded to osteoarthritis and nonunion in distal humeral fractures. Information on implant survival and risk factors for revision is still sparse. The aim of this study...... was to evaluate implant survival and risk factors for revision of TEAs inserted in patients in the eastern part of Denmark in the period from 1980 until 2008. MATERIAL AND METHODS: The Danish National Patient Register provided personal identification numbers for patients who underwent TEA procedures from 1980...... until 2008. On the basis of a review of medical reports and linkage to the National Patient Register, we calculated revision rates and evaluated potential risk factors for revision, including, age, sex, period, indication for TEA, and implant design. RESULTS: We evaluated 324 primary TEA procedures...

  4. Epidemic and Cascading Survivability of Complex Networks

    DEFF Research Database (Denmark)

    Manzano, Marc; Calle, Eusebi; Ripoll, Jordi

    2014-01-01

    Our society nowadays is governed by complex networks, examples being the power grids, telecommunication networks, biological networks, and social networks. It has become of paramount importance to understand and characterize the dynamic events (e.g. failures) that might happen in these complex...... networks. For this reason, in this paper, we propose two measures to evaluate the vulnerability of complex networks in two different dynamic multiple failure scenarios: epidemic-like and cascading failures. Firstly, we present epidemic survivability ( ES ), a new network measure that describes...... the vulnerability of each node of a network under a specific epidemic intensity. Secondly, we propose cascading survivability ( CS ), which characterizes how potentially injurious a node is according to a cascading failure scenario. Then, we show that by using the distribution of values obtained from ES and CS...

  5. Survivability design for a hybrid underwater vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Biao; Wu, Chao; Li, Xiang; Zhao, Qingkai; Ge, Tong [State Key Lab of Ocean Engineering, School of Naval Architecture, Ocean and Civil Engineering, Shanghai Jiao Tong University, Shanghai 200240 (China)

    2015-03-10

    A novel hybrid underwater robotic vehicle (HROV) capable of working to the full ocean depth has been developed. The battery powered vehicle operates in two modes: operate as an untethered autonomous vehicle in autonomous underwater vehicle (AUV) mode and operate under remote control connected to the surface vessel by a lightweight, fiber optic tether in remotely operated vehicle (ROV) mode. Considering the hazardous underwater environment at the limiting depth and the hybrid operating modes, survivability has been placed on an equal level with the other design attributes of the HROV since the beginning of the project. This paper reports the survivability design elements for the HROV including basic vehicle design of integrated navigation and integrated communication, emergency recovery strategy, distributed architecture, redundant bus, dual battery package, emergency jettison system and self-repairing control system.

  6. Cell survival in a simulated Mars environment

    Science.gov (United States)

    Todd, Paul; Kurk, Michael Andy; Boland, Eugene; Thomas, David

    2016-07-01

    The most ancient life forms on earth date back comfortably to the time when liquid water was believed to be abundant on Mars. These ancient life forms include cyanobacteria, contemporary autotrophic earth organisms believed to have descended from ancestors present as long as 3.5 billion years ago. Contemporary cyanobacteria have adapted to the earth environment's harshest conditions (long-term drying, high and low temperature), and, being autotrophic, they are among the most likely life forms to withstand space travel and the Mars environment. However, it is unlikely that humans would unwittingly contaminate a planetary spacecraft with these microbes. One the other hand, heterotrophic microbes that co-habit with humans are more likely spacecraft contaminants, as history attests. Indeed, soil samples from the Atacama desert have yielded colony-forming organisms resembling enteric bacteria. There is a need to understand the survivability of cyanobacteria (likely survivors, unlikely contaminants) and heterotrophic eubacteria (unlikely survivors, likely contaminants) under simulated planetary conditions. A 35-day test was performed in a commercial planetary simulation system (Techshot, Inc., Greenville, IN) in which the minimum night-time temperature was -80 C, the maximum daytime temperature was +26 C, the simulated day-night light cycle in earth hours was 12-on and 12-off, and the total pressure of the pure CO _{2} atmosphere was maintained below 11 mbar. Any water present was allowed to equilibrate with the changing temperature and pressure. The gas phase was sampled into a CR1-A low-pressure hygrometer (Buck Technologies, Boulder, CO), and dew/frost point was measured once every hour and recorded on a data logger, along with the varying temperature in the chamber, from which the partial pressure of water was calculated. According to measurements there was no liquid water present throughout the test except during the initial pump-down period when aqueous specimens

  7. Mental vulnerability and survival after cancer

    DEFF Research Database (Denmark)

    Nakaya, Naoki; Bidstrup, Pernille E; Eplov, Lene F

    2009-01-01

    BACKGROUND: It has been hypothesized that personality traits affect survival after cancer, but studies have produced inconsistent results. This study examined the association between mental vulnerability and survival after cancer in Denmark in a prospective cohort study. METHODS: Between 1976...... and 2001, 12733 residents of Copenhagen completed a questionnaire eliciting information on a 12-item mental vulnerability scale, as well as various personal data. Follow-up in the Danish Cancer Registry until 2003 identified 884 incident cases of primary cancer, and follow-up for death from the date...... of cancer diagnosis until 2003 identified 382 deaths. Mental vulnerability scores were divided into 4 approximately equal-sized groups. Cox proportional hazards regression models were used to estimate the hazard ratio (HR) of all-cause mortality. RESULTS: Multivariate HR for all-cause mortality for persons...

  8. Epidemic and Cascading Survivability of Complex Networks

    CERN Document Server

    Manzano, Marc; Ripoll, Jordi; Fagertun, Anna Manolova; Torres-Padrosa, Victor; Pahwa, Sakshi; Scoglio, Caterina

    2014-01-01

    Our society nowadays is governed by complex networks, examples being the power grids, telecommunication networks, biological networks, and social networks. It has become of paramount importance to understand and characterize the dynamic events (e.g. failures) that might happen in these complex networks. For this reason, in this paper, we propose two measures to evaluate the vulnerability of complex networks in two different dynamic multiple failure scenarios: epidemic-like and cascading failures. Firstly, we present \\emph{epidemic survivability} ($ES$), a new network measure that describes the vulnerability of each node of a network under a specific epidemic intensity. Secondly, we propose \\emph{cascading survivability} ($CS$), which characterizes how potentially injurious a node is according to a cascading failure scenario. Then, we show that by using the distribution of values obtained from $ES$ and $CS$ it is possible to describe the vulnerability of a given network. We consider a set of 17 different compl...

  9. Diverse microbial species survive high ammonia concentrations

    Science.gov (United States)

    Kelly, Laura C.; Cockell, Charles S.; Summers, Stephen

    2012-04-01

    Planetary protection regulations are in place to control the contamination of planets and moons with terrestrial micro-organisms in order to avoid jeopardizing future scientific investigations relating to the search for life. One environmental chemical factor of relevance in extraterrestrial environments, specifically in the moons of the outer solar system, is ammonia (NH3). Ammonia is known to be highly toxic to micro-organisms and may disrupt proton motive force, interfere with cellular redox reactions or cause an increase of cell pH. To test the survival potential of terrestrial micro-organisms exposed to such cold, ammonia-rich environments, and to judge whether current planetary protection regulations are sufficient, soil samples were exposed to concentrations of NH3 from 5 to 35% (v/v) at -80°C and room temperature for periods up to 11 months. Following exposure to 35% NH3, diverse spore-forming taxa survived, including representatives of the Firmicutes (Bacillus, Sporosarcina, Viridibacillus, Paenibacillus, Staphylococcus and Brevibacillus) and Actinobacteria (Streptomyces). Non-spore forming organisms also survived, including Proteobacteria (Pseudomonas) and Actinobacteria (Arthrobacter) that are known to have environmentally resistant resting states. Clostridium spp. were isolated from the exposed soil under anaerobic culture. High NH3 was shown to cause a reduction in viability of spores over time, but spore morphology was not visibly altered. In addition to its implications for planetary protection, these data show that a large number of bacteria, potentially including spore-forming pathogens, but also environmentally resistant non-spore-formers, can survive high ammonia concentrations.

  10. Antibiotics Reduce Retinal Cell Survival In Vitro.

    Science.gov (United States)

    Lindsey, Amy E; Townes-Anderson, Ellen

    2017-11-02

    Antibiotics such as gentamicin (an aminoglycoside) and penicillin (a beta-lactam antibiotic) are routinely used in retinal cell and explant cultures. In many cases, these in vitro systems are testing parameters regarding photoreceptor transplantation or preparing cells for transplantation. In vivo, milligram doses of gentamicin are neurotoxic to the retina. However, little is known about the effects of antibiotics to retina in vitro and whether smaller doses of gentamicin are toxic to retinal cells. To test toxicity, retinal cells were dissociated from tiger salamander, placed in culture, and treated with either 20 μg/ml gentamicin, 100 μg/ml streptomycin, 100 U/ml antibiotic/antimycotic, 0.25 μg/ml amphotericin B, or 100 U/ml penicillin G. All dosages were within manufacturer's recommended levels. Control cultures had defined medium only. Cells were fixed at 2 h or 7 days. Three criteria were used to assess toxicity: (1) survival of retinal neurons, (2) neuritic growth of photoreceptors assessed by the development of presynaptic varicosities, and (3) survival and morphology of Mueller cells. Rod cells were immunolabeled for rod opsin, Mueller cells for glial fibrillary acidic protein, and varicosities for synaptophysin. Neuronal cell density was reduced with all pharmacological treatments. The number of presynaptic varicosities was also significantly lower in both rod and cone photoreceptors in treated compared to control cultures; further, rods were more sensitive to gentamicin than cones. Penicillin G (100 U/ml) was overall the least inhibitory and amphotericin B the most toxic of all the agents to photoreceptors. Mueller cell survival was reduced with all treatments; reduced survival was accompanied by the appearance of proportionally fewer stellate and more rounded glial morphologies. These findings suggest that even microgram doses of antibiotic and antimycotic drugs can be neurotoxic to retinal cells and reduce neuritic regeneration in cell

  11. Survival of severe acute respiratory syndrome coronavirus.

    Science.gov (United States)

    Lai, Mary Y Y; Cheng, Peter K C; Lim, Wilina W L

    2005-10-01

    The primary modes of transmission of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) appear to be direct mucus membrane contact with infectious droplets and through exposure to formites. Knowledge of the survival characteristics of the virus is essential for formulating appropriate infection-control measures. Survival of SARS-CoV strain GVU6109 was studied in stool and respiratory specimens. Survival of the virus on different environmental surfaces, including a laboratory request form, an impervious disposable gown, and a cotton nondisposable gown, was investigated. The virucidal effects of sodium hypochlorite, house detergent, and a peroxygen compound (Virkon S; Antec International) on the virus were also studied. SARS-CoV GVU6109 can survive for 4 days in diarrheal stool samples with an alkaline pH, and it can remain infectious in respiratory specimens for >7 days at room temperature. Even at a relatively high concentration (10(4) tissue culture infective doses/mL), the virus could not be recovered after drying of a paper request form, and its infectivity was shown to last longer on the disposable gown than on the cotton gown. All disinfectants tested were shown to be able to reduce the virus load by >3 log within 5 min. Fecal and respiratory samples can remain infectious for a long period of time at room temperature. The risk of infection via contact with droplet-contaminated paper is small. Absorbent material, such as cotton, is preferred to nonabsorptive material for personal protective clothing for routine patient care where risk of large spillage is unlikely. The virus is easily inactivated by commonly used disinfectants.

  12. Altruism: A natural strategy for enhancing survival

    Science.gov (United States)

    Rozenfeld, Alejandro F.; Luis Gruver, José; Albano, Ezequiel V.; Havlin, Shlomo

    2006-09-01

    We study the influence of altruistic behavior in a prey-predator model permitting the preys to commit suicide by confronting the predators instead of escaping. Surprising, altruistic behavior at microscopic (local) scale, leads to the emergence of new complex macroscopic (global) phenomena characterized by dramatic changes in the dynamic topology of the prey-predator spatiotemporal distribution, yielding spiral patterns. We show that such dynamics enhances the prey's survivability.

  13. Survival after in-hospital Cardiopulmonary Resuscitation

    OpenAIRE

    M Adib Hajbaghery; Akbari, H.; GA Mousavi

    2005-01-01

    Background: During recent years, cardiopulmonary resuscitation (CPR) in hospital has received much attention. However, the survival rate of CPR in Iran’s hospitals is unknown. This study was designed to evaluate outcome of in-hospital CPR in Kashan. Methods: A longitudinal case registry study was conducted on all cases of in-hospital CPR during 6 months at 2002. Necessary data including; age, sex, underlying disease, working shift, time from cardiac arrest until initiating of CPR and unt...

  14. Estimating haplotype effects for survival data

    DEFF Research Database (Denmark)

    Scheike, Thomas; Martinussen, Torben; Silver, J

    2010-01-01

    Genetic association studies often investigate the effect of haplotypes on an outcome of interest. Haplotypes are not observed directly, and this complicates the inclusion of such effects in survival models. We describe a new estimating equations approach for Cox's regression model to assess haplo...... in this article to investigate possible haplotype effects of the PAF-receptor on cardiovascular events in patients with coronary artery disease, and compare our results to those based on the EM algorithm....

  15. Hip Fracture Surgery and Survival in Centenarians.

    Science.gov (United States)

    Mazzola, Paolo; Rea, Federico; Merlino, Luca; Bellelli, Giuseppe; Dubner, Lauren; Corrao, Giovanni; Pasinetti, Giulio M; Annoni, Giorgio

    2016-11-01

    Hip fracture (HF) is increasingly frequent with advancing age. Studies describing the HF incidence rate and survival after surgery in centenarians are scanty. To fill this gap, we performed a large population-based investigation on Lombardy centenarians (Italy). Retrospective observational cohort study based on information from the Healthcare Utilization Database. Among the cohort of 7,830 residents that reached 100 years of age between 2004 and 2011, incidence rate of HF was calculated. Two hundred fifty-nine patients were discharged alive from a hospital after HF and surgical repair (HF cohort). For each HF cohort member, a control was randomly selected from the initial cohort to be matched for gender and date of birth, and who did not experience HF from the date of their hundredth birthday until the date of hospital discharge of the corresponding HF cohort member. The survival curves and the hazard functions of HF and control cohort were calculated within 2 years. Over a mean follow-up of 1.85 years, HF incidence rate was 23.1 per 1,000 centenarians per year. Survival probability was significantly lower in HF cohort than in control cohort (31.5 vs 48.1%, p < .001). Hazard functions showed an increased risk of death in HF cohort than in control cohort, especially in the 3 months after surgery. Survival analysis exhibited an excess mortality in the first 3 months among HF cohort members, but not beyond this period. Every effort to counteract HF is warranted, including prevention of falls and high quality of care, especially in the early postsurgical time. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Nivolumab Doubles Survival for Patients with HNSCC.

    Science.gov (United States)

    2016-07-01

    In patients with head and neck squamous cell carcinoma refractory to platinum-based chemotherapy, those treated with nivolumab had a 30% reduction in the risk of death compared with those assigned to receive one of three single-agent chemotherapies, according to a recent phase III trial. In addition, 1-year survival among nivolumab recipients was double that of those who received a chemotherapeutic, the current standard of care. ©2016 American Association for Cancer Research.

  17. Longevity and Patau syndrome: what determines survival?

    OpenAIRE

    Peroos, Sherina; Forsythe, Elizabeth; Pugh, Jennifer Harriet; Arthur-Farraj, Peter; Hodes, Deborah

    2012-01-01

    The authors report of an 8-year-old girl with non-mosaic Patau syndrome. The median life expectancy of Patau syndrome is 7–10 days, and 90% die in the first year of life. Survival is often attributed to mosaicism and the severity of associated malformations. We delineate the developing phenotype and review the literature discussing potential contributory factors to longevity.

  18. Pretension Strategy in the Surviving Game

    Directory of Open Access Journals (Sweden)

    Andrejs JAUNZEMS

    2014-07-01

    Full Text Available Till the nowadays we cannot find the scientific analysis that clearly explains the deepest roots of global economical and moral crisis. Because of that many famous politicians, economists, sociologists denote the understanding of current situation as the most valuable attainment. Under traditional influence of the doctrine of spontaneous harmony of egoistic individual behavior many economists believe that competition and private property rights through the markets' price mechanism leads in the long run to the Pareto efficient equilibrium. In the same time the social and economic reality categorically asks for ascertain the market failure and for revision the classical statements of microeconomics. The perfect competition market has lost its attributes due to dialectics of interactions of agents. The investigation of the strategies interactions of the individuals are based on the game theory, what helps to understand also the role of asymmetric information as specific market failure factor. In present paper the Martin Shubik classical surviving game is analyzed and some statements of Herbert Gintis concerning this game are critically appraised. The solution of Martin Shubik game in the original geometrical form is offered. The problem of Martin Shubik "does the fittest necessary survive?" is transformed according the case of asymmetric information in problem "does the pretender survive?", for which the answer "if the agent is not the weakest, but he pretends to be the weakest, than this agent survives with high probability" is offered. The results of the present paper appear to be innovative, not discussed in literature available to the author of the present paper.

  19. Obesity and gynecologic cancer etiology and survival.

    Science.gov (United States)

    Webb, Penelope M

    2013-01-01

    The prevalence of overweight and obesity in the United States and elsewhere has increased dramatically in recent decades. It has long been known that obese women have an increased risk of developing endometrial cancer, but recent studies suggest this association is strongest for the most common low-grade endometrioid endometrial cancers and weaker for the other histologic subtypes. There are insufficient data to assess whether obesity affects endometrial cancer-specific survival or whether the relation with all-cause mortality is similar to that seen in the general population. Recent data suggest obesity also increases risk of ovarian cancer, although it may not influence risk of the high-grade serous cancers that account for the majority of ovarian cancer deaths, and that it is also associated with poorer outcomes. There is currently insufficient evidence to draw any clear conclusions regarding the relation between obesity and risk of/survival from other gynecologic cancers although there are suggestions that obesity may increase risk of cervical cancer, particularly adenocarcinoma, and perhaps vulvar cancer. Possible mechanisms whereby obesity might influence gynecologic cancer risk and survival include: its strong association with endogenous estrogen levels among postmenopausal women, its effects on glucose metabolism, its effects on the wide range of adipocytokines and inflammatory mediators that are produced by adipose tissue and altered in concentration among obese individuals, and its potential effects on patient management, particularly with regard to chemotherapy dosing.

  20. Neuronal survival induced by neurotrophins requires calmodulin

    Science.gov (United States)

    Egea, Joaquim; Espinet, Carme; Soler, Rosa M.; Dolcet, Xavier; Yuste, Víctor J.; Encinas, Mario; Iglesias, Montserrat; Rocamora, Nativitat; Comella, Joan X.

    2001-01-01

    It has been reported that phosphoinositide 3-kinase (PI 3-kinase) and its downstream target, protein kinase B (PKB), play a central role in the signaling of cell survival triggered by neurotrophins (NTs). In this report, we have analyzed the involvement of Ca2+ and calmodulin (CaM) in the activation of the PKB induced by NTs. We have found that reduction of intracellular Ca2+ concentration or functional blockade of CaM abolished NGF-induced activation of PKB in PC12 cells. Similar results were obtained in cultures of chicken spinal cord motoneurons treated with brain-derived neurotrophic factor (BDNF). Moreover, CaM inhibition prevented the cell survival triggered by NGF or BDNF. This effect was counteracted by the transient expression of constitutive active forms of the PKB, indicating that CaM regulates NT-induced cell survival through the activation of the PKB. We have investigated the mechanisms whereby CaM regulates the activation of the PKB, and we have found that CaM was necessary for the proper generation and/or accumulation of the products of the PI 3-kinase in intact cells. PMID:11489918

  1. A Multidomain Survivable Virtual Network Mapping Algorithm

    Directory of Open Access Journals (Sweden)

    Xiancui Xiao

    2017-01-01

    Full Text Available Although the existing networks are more often deployed in the multidomain environment, most of existing researches focus on single-domain networks and there are no appropriate solutions for the multidomain virtual network mapping problem. In fact, most studies assume that the underlying network can operate without any interruption. However, physical networks cannot ensure the normal provision of network services for external reasons and traditional single-domain networks have difficulties to meet user needs, especially for the high security requirements of the network transmission. In order to solve the above problems, this paper proposes a survivable virtual network mapping algorithm (IntD-GRC-SVNE that implements multidomain mapping in network virtualization. IntD-GRC-SVNE maps the virtual communication networks onto different domain networks and provides backup resources for virtual links which improve the survivability of the special networks. Simulation results show that IntD-GRC-SVNE can not only improve the survivability of multidomain communications network but also render the network load more balanced and greatly improve the network acceptance rate due to employment of GRC (global resource capacity.

  2. Survival of the scarcer in space

    Science.gov (United States)

    Vieira dos Santos, Renato; Dickman, Ronald

    2013-07-01

    The dynamics leading to extinction or coexistence of competing species is of great interest in ecology and related fields. Recently a model of intra- and interspecific competition between two species was proposed by Gabel et al, in which the scarcer species (i.e., with smaller stationary population size) can be more resistant to extinction when it holds a competitive advantage; the latter study considered populations without spatial variation. Here we verify this phenomenon in populations distributed in space. We extend the model of Gabel et al to a d-dimensional lattice, and study its population dynamics both analytically and numerically. Survival of the scarcer in space is verified for situations in which the more competitive species is closer to the threshold for extinction than is the less competitive species, when considered in isolation. The conditions for survival of the scarcer species, as obtained applying renormalization group analysis and Monte Carlo simulation, differ in detail from those found in the spatially homogeneous case. Simulations highlight the speed of invasion waves in determining the survival times of the competing species.

  3. Nutritional factors in ovarian cancer survival.

    Science.gov (United States)

    Bandera, Elisa V; Kushi, Lawrence H; Rodriguez-Rodriguez, Lorna

    2009-01-01

    Ovarian cancer is the leading cause of death from gynecologic malignancies in the United States. Because symptoms tend be nonspecific, early detection is difficult, and most ovarian cancers are diagnosed at an advanced stage when the prognosis is poor. Nonetheless, there is clinical evidence that even given the same tumor characteristics (histologic type, stage, and grade), some cases experience much better survival than others. This has led to extensive research on molecular prognostic factors to enable more efficient and targeted therapeutic regimens. However, little is known about the impact that lifestyle factors, such as diet or physical activity, may have in the prognosis of ovarian cancer, whether on disease-free survival or on the response to and complications from treatment. The role of obesity on ovarian cancer survival is unclear. Obesity may delay diagnosis, hinder optimal surgical and cytotoxic treatment, and cause postoperative complications. As overweight and obesity rates reach epidemic proportions, the impact of body mass index in the clinical management of ovarian cancer is increasingly significant, whereas current evidence of its impact is limited and inconclusive.

  4. Dietary Patterns and Survival of Older Adults

    Science.gov (United States)

    ANDERSON, AMY L.; HARRIS, TAMARA B.; TYLAVSKY, FRANCES A.; PERRY, SARA E.; HOUSTON, DENISE K.; HUE, TRISHA F.; STROTMEYER, ELSA S.; SAHYOUN, NADINE R.

    2013-01-01

    Background Recent research has linked overall dietary patterns to survival in older adults. Objectives The objective of this study was to determine the dietary patterns of a cohort of older adults, and to explore associations of these dietary patterns with survival over a 10-year period. A secondary goal was to evaluate participants’ quality of life and nutritional status according to their dietary patterns. Design The Health, Aging, and Body Composition Study is a prospective cohort study of 3,075 older adults. In this study, all-cause mortality was assessed from baseline through Year 10. Food intake was estimated with a modified Block food frequency questionnaire, and dietary patterns of 2,582 participants with complete data were derived by cluster analysis. Results Six dietary pattern clusters were identified, including a Healthy Foods cluster, characterized by higher intake of low-fat dairy products, fruit, whole grains, poultry, fish, and vegetables. Both the High-Fat Dairy Products and Sweets and Desserts clusters had a 1.4-fold higher risk of mortality than the Healthy Foods cluster after adjusting for potential confounders. The Healthy Foods cluster also had significantly more years of healthy life and more favorable levels of selected nutritional biomarkers than the other clusters. Conclusions A dietary pattern consistent with current guidelines to consume relatively high amounts of vegetables, fruit, whole grains, poultry, fish, and low-fat dairy products may be associated with superior nutritional status, quality of life and survival in older adults. PMID:21185969

  5. Presentation and management of pediatric orbital cellulitis.

    Science.gov (United States)

    Fanella, Sergio; Singer, Alex; Embree, Joanne

    2011-01-01

    Orbital cellulitis is a serious, vision-threatening infection. To review the epidemiology and clinical data of pediatric orbital cellulitis in Manitoba. A 12-year retrospective review was conducted of all children (younger than 18 years of age) with orbital cellulitis admitted to Manitoba's only tertiary pediatric centre. Admission rates for orbital cellulitis were compared over three distinct time periods, based on licensure and funding levels of the heptavalent pneumococcal conjugate vaccine (PCV7) in Manitoba. Thirty-eight patients with orbital cellulitis were identified. Of these, 11% were of Aboriginal ethnicity in contrast with 30% to 40% of children who were admitted for other respiratory illnesses. Subperiosteal abscesses occurred in 31.5%. Only eight patients (21%) required surgery. Follow-up imaging after presentation usually did not indicate a need for subsequent surgical drainage. The mean number of orbital cellulitis cases per 1000 admissions for the following periods - before PCV7 licensure, after licensure and before full provincial funding, and after licensure and full funding - were 0.39, 0.53 and 0.90, respectively. No significant difference was noted among any of the periods as PCV7 coverage increased. The rate of subperiosteal abscesses was lower than other reports. This may be due to the median age at presentation. In contrast to admissions for most other respiratory infections at the Winnipeg Children's Hospital (Winnipeg, Manitoba), Aboriginal ethnicity was uncommon. Surprisingly, rates of admissions for orbital cellulitis appeared to show an increasing trend with increasing access to PCV7 in Manitoba, although overall the number of cases was very small. Studies into the changing microbiology of orbital cellulitis and sinusitis are warranted.

  6. Survival of Salmonella Newport in oysters.

    Science.gov (United States)

    Morrison, Christopher M; Armstrong, Alexandra E; Evans, Sanford; Mild, Rita M; Langdon, Christopher J; Joens, Lynn A

    2011-08-02

    Salmonella enterica is the leading cause of laboratory-confirmed foodborne illness in the United States and raw shellfish consumption is a commonly implicated source of gastrointestinal pathogens. A 2005 epidemiological study done in our laboratory by Brands et al., showed that oysters in the United States are contaminated with Salmonella, and in particular, a specific strain of the Newport serovar. This work sought to further investigate the host-microbe interactions between Salmonella Newport and oysters. A procedure was developed to reliably and repeatedly expose oysters to enteric bacteria and quantify the subsequent levels of bacterial survival. The results show that 10 days after an exposure to Salmonella Newport, an average concentration of 3.7 × 10(3)CFU/g remains within the oyster meat, and even after 60 days there still can be more than 10(2)CFU/g remaining. However, the strain of Newport that predominated in the market survey done by Brands et al. does not survive within oysters or the estuarine environment better than any other strains of Salmonella we tested. Using this same methodology, we compared Salmonella Newport's ability to survive within oysters to a non-pathogenic strain of E. coli and found that after 10 days the concentration of Salmonella was 200-times greater than that of E. coli. We also compared those same strains of Salmonella and E. coli in a depuration process to determine if a constant 120 L/h flux of clean seawater could significantly reduce the concentration of bacteria within oysters and found that after 3 days the oysters retained over 10(4)CFU/g of Salmonella while the oysters exposed to the non-pathogenic strain of E. coli contained 100-times less bacteria. Overall, the results of this study demonstrate that any of the clinically relevant serovars of Salmonella can survive within oysters for significant periods of time after just one exposure event. Based on the drastic differences in survivability between Salmonella and a non

  7. Escherichia coli survival in waters: temperature dependence.

    Science.gov (United States)

    Blaustein, R A; Pachepsky, Y; Hill, R L; Shelton, D R; Whelan, G

    2013-02-01

    Knowing the survival rates of water-borne Escherichia coli is important in evaluating microbial contamination and making appropriate management decisions. E. coli survival rates are dependent on temperature, a dependency that is routinely expressed using an analogue of the Q₁₀ model. This suggestion was made 34 years ago based on 20 survival curves taken from published literature, but has not been revisited since then. The objective of this study was to re-evaluate the accuracy of the Q₁₀ equation, utilizing data accumulated since 1978. We assembled a database of 450 E. coli survival datasets from 70 peer-reviewed papers. We then focused on the 170 curves taken from experiments that were performed in the laboratory under dark conditions to exclude the effects of sunlight and other field factors that could cause additional variability in results. All datasets were tabulated dependencies "log concentration vs. time." There were three major patterns of inactivation: about half of the datasets had a section of fast log-linear inactivation followed by a section of slow log-linear inactivation; about a quarter of the datasets had a lag period followed by log-linear inactivation; and the remaining quarter were approximately linear throughout. First-order inactivation rate constants were calculated from the linear sections of all survival curves and the data grouped by water sources, including waters of agricultural origin, pristine water sources, groundwater and wells, lakes and reservoirs, rivers and streams, estuaries and seawater, and wastewater. Dependency of E. coli inactivation rates on temperature varied among the water sources. There was a significant difference in inactivation rate values at the reference temperature between rivers and agricultural waters, wastewaters and agricultural waters, rivers and lakes, and wastewater and lakes. At specific sites, the Q₁₀ equation was more accurate in rivers and coastal waters than in lakes making the value of

  8. Diabetes, metformin use, and colorectal cancer survival in postmenopausal women

    National Research Council Canada - National Science Library

    Cossor, Furha Iram; Adams-Campbell, Lucile L; Chlebowski, Rowan T; Gunter, Marc J; Johnson, Karen; Martell, Robert E; McTiernan, Anne; Simon, Michael S; Rohan, Thomas; Wallace, Robert B; Paulus, Jessica K

    2013-01-01

    ...) incidence but few studies have examined metformin's influence on CRC survival. We examined the relationships among metformin use, diabetes, and survival in postmenopausal women with CRC in the Women's Health Initiative (WHI...

  9. Soluble L-selectin levels predict survival in sepsis

    DEFF Research Database (Denmark)

    Seidelin, Jakob B; Nielsen, Ole H; Strøm, Jens

    2002-01-01

    To evaluate serum soluble L-selectin as a prognostic factor for survival in patients with sepsis.......To evaluate serum soluble L-selectin as a prognostic factor for survival in patients with sepsis....

  10. Effect of ponderosa pine needle litter on grass seedling survival.

    Science.gov (United States)

    Burt R. McConnell; Justin G. Smith

    1971-01-01

    Hard fescue survival rates were followed for 6 years on four different pine needle treatment plots. Needle litter had a significant effect on initial survival of fescue seedlings, but subsequent losses undoubtedly resulted from the interaction of many factors.

  11. Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival

    Science.gov (United States)

    ... Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival For some women with breast cancer , taking adjuvant ... Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival was originally published by the National Cancer Institute.” ...

  12. Dying to remember, remembering to survive: mortality salience and survival processing.

    Science.gov (United States)

    Burns, Daniel J; Hart, Joshua; Kramer, Melanie E; Burns, Amy D

    2014-01-01

    Processing items for their relevance to survival improves recall for those items relative to numerous other deep processing encoding techniques. Perhaps related, placing individuals in a mortality salient state has also been shown to enhance retention of items encoded after the morality salience manipulation (e.g., in a pleasantness rating task), a phenomenon we dubbed the "dying-to-remember" (DTR) effect. The experiments reported here further explored the effect and tested the possibility that the DTR effect is related to survival processing. Experiment 1 replicated the effect using different encoding tasks, demonstrating that the effect is not dependent on the pleasantness task. In Experiment 2 the DTR effect was associated with increases in item-specific processing, not relational processing, according to several indices. Experiment 3 replicated the main results of Experiment 2, and tested the effects of mortality salience and survival processing within the same experiment. The DTR effect and its associated difference in item-specific processing were completely eliminated when the encoding task required survival processing. These results are consistent with the interpretation that the mechanisms responsible for survival processing and DTR effects are overlapping.

  13. Social class and survival on the S.S. Titanic.

    Science.gov (United States)

    Hall, W

    1986-01-01

    Passengers' chances of surviving the sinking of the S.S. Titanic were related to their sex and their social class: females were more likely to survive than males, and the chances of survival declined with social class as measured by the class in which the passenger travelled. The probable reasons for these differences in rates of survival are discussed as are the reasons accepted by the Mersey Committee of Inquiry into the sinking.

  14. Survival on Home Dialysis in New Zealand

    Science.gov (United States)

    Marshall, Mark R.; Walker, Rachael C.; Polkinghorne, Kevan R.; Lynn, Kelvin L.

    2014-01-01

    Background New Zealand (NZ) has a high prevalence of both peritoneal dialysis (PD) and home haemodialysis (HD) relative to other countries, and probably less selection bias. We aimed to determine if home dialysis associates with better survival than facility HD by simultaneous comparisons of the three modalities. Methods We analysed survival by time-varying dialysis modality in New Zealanders over a 15-year period to 31-Dec-2011, adjusting for patient co-morbidity by Cox proportional hazards multivariate regression. Results We modelled 6,419 patients with 3,254 deaths over 20,042 patient-years of follow-up. Patients treated with PD and facility HD are similar; those on home HD are younger and healthier. Compared to facility HD, home dialysis (as a unified category) associates with an overall 13% lower mortality risk. Home HD associates with a 52% lower mortality risk. PD associates with a 20% lower mortality risk in the early period (3 years), with no overall net effect. There was effect modification and less observable benefit associated with PD in those with diabetes mellitus, co-morbidity, and in NZ Maori and Pacific People. There was no effect modification by age or by era. Conclusion Our study supports the culture of home dialysis in NZ, and suggests that the extent and duration of survival benefit associated with early PD may be greater than appreciated. We are planning further analyses to exclude residual confounding from unmeasured co-morbidity and other sociodemographic factors using database linkage to NZ government datasets. Finally, our results suggest further research into the practice of PD in NZ Maori and Pacific People, as well as definitive study to determine the best timing for switching from PD in the late phase. PMID:24806458

  15. Glioblastoma multiforme with long term survival.

    Science.gov (United States)

    Deb, Prabal; Sharma, Mehar Chand; Mahapatra, Ashok Kumar; Agarwal, Deepak; Sarkar, Chitra

    2005-09-01

    Glioblastoma multiforme (GBM) Patients generally have a dismal prognosis, with median survival of 10-12 months. GBM with long-term survival (LTS) of (3) > or = 5 years is rare, and no definite markers indicating better prognosis have been identified till date. The present study was undertaken to evaluate GBMs with LTS in order to identify additional correlates associated with favourable outcome. The cases were evaluated for relevant clinicopathological data, proliferation index and expression of tumortumour suppressor gene (p53 ), cyclin-dependant kinase-inhibitors (p27 and p16 ) and epidermal growth factor receptor (EGFR) proteins. Six cases of GBM with LTS with an average survival of 9 years (range 5-15 years) were identified. All were young patients with mean age of 27 years (range 8-45 years). Histology of three cases was consistent with conventional GBM, while two showed prominent oligodendroglial component admixed with GBM areas. One was a giant cell GBM, which progressed to gliosarcoma on recurrence. The mean MIB-1LI was 12% (range 6-20%). p53 was immunopositive in 4 out of 5 cases. EGFR and p27 were immunonegative in all, whereas p16 was immunonegative in 3 out of 5 cases. Currently, in the absence of specific molecular and genetic markers, GBM in young patients should be meticulously evaluated for foci of oligodendroglial component and/or giant cell elements, in addition to proliferative index and p53 expression, since these probably have prognostic connotations, as evident in this study. The role of p16 and p27 however needs better definition with study of more number of cases.

  16. Dietary patterns and survival of older adults.

    Science.gov (United States)

    Anderson, Amy L; Harris, Tamara B; Tylavsky, Frances A; Perry, Sara E; Houston, Denise K; Hue, Trisha F; Strotmeyer, Elsa S; Sahyoun, Nadine R

    2011-01-01

    Recent research has linked overall dietary patterns to survival in older adults. The objective of this study was to determine the dietary patterns of a cohort of older adults, and to explore associations of these dietary patterns with survival over a 10-year period. A secondary goal was to evaluate participants' quality of life and nutritional status according to their dietary patterns. The Health, Aging, and Body Composition Study is a prospective cohort study of 3,075 older adults. In this study, all-cause mortality was assessed from baseline through Year 10. Food intake was estimated with a modified Block food frequency questionnaire, and dietary patterns of 2,582 participants with complete data were derived by cluster analysis. Six dietary pattern clusters were identified, including a Healthy Foods cluster, characterized by higher intake of low-fat dairy products, fruit, whole grains, poultry, fish, and vegetables. Both the High-Fat Dairy Products and Sweets and Desserts clusters had a 1.4-fold higher risk of mortality than the Healthy Foods cluster after adjusting for potential confounders. The Healthy Foods cluster also had significantly more years of healthy life and more favorable levels of selected nutritional biomarkers than the other clusters. A dietary pattern consistent with current guidelines to consume relatively high amounts of vegetables, fruit, whole grains, poultry, fish, and low-fat dairy products may be associated with superior nutritional status, quality of life and survival in older adults. Copyright © 2011 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

  17. Covariate analysis of bivariate survival data

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, L.E.

    1992-01-01

    The methods developed are used to analyze the effects of covariates on bivariate survival data when censoring and ties are present. The proposed method provides models for bivariate survival data that include differential covariate effects and censored observations. The proposed models are based on an extension of the univariate Buckley-James estimators which replace censored data points by their expected values, conditional on the censoring time and the covariates. For the bivariate situation, it is necessary to determine the expectation of the failure times for one component conditional on the failure or censoring time of the other component. Two different methods have been developed to estimate these expectations. In the semiparametric approach these expectations are determined from a modification of Burke's estimate of the bivariate empirical survival function. In the parametric approach censored data points are also replaced by their conditional expected values where the expected values are determined from a specified parametric distribution. The model estimation will be based on the revised data set, comprised of uncensored components and expected values for the censored components. The variance-covariance matrix for the estimated covariate parameters has also been derived for both the semiparametric and parametric methods. Data from the Demographic and Health Survey was analyzed by these methods. The two outcome variables are post-partum amenorrhea and breastfeeding; education and parity were used as the covariates. Both the covariate parameter estimates and the variance-covariance estimates for the semiparametric and parametric models will be compared. In addition, a multivariate test statistic was used in the semiparametric model to examine contrasts. The significance of the statistic was determined from a bootstrap distribution of the test statistic.

  18. Survival on home dialysis in New Zealand.

    Directory of Open Access Journals (Sweden)

    Mark R Marshall

    Full Text Available BACKGROUND: New Zealand (NZ has a high prevalence of both peritoneal dialysis (PD and home haemodialysis (HD relative to other countries, and probably less selection bias. We aimed to determine if home dialysis associates with better survival than facility HD by simultaneous comparisons of the three modalities. METHODS: We analysed survival by time-varying dialysis modality in New Zealanders over a 15-year period to 31-Dec-2011, adjusting for patient co-morbidity by Cox proportional hazards multivariate regression. RESULTS: We modelled 6,419 patients with 3,254 deaths over 20,042 patient-years of follow-up. Patients treated with PD and facility HD are similar; those on home HD are younger and healthier. Compared to facility HD, home dialysis (as a unified category associates with an overall 13% lower mortality risk. Home HD associates with a 52% lower mortality risk. PD associates with a 20% lower mortality risk in the early period (3 years, with no overall net effect. There was effect modification and less observable benefit associated with PD in those with diabetes mellitus, co-morbidity, and in NZ Maori and Pacific People. There was no effect modification by age or by era. CONCLUSION: Our study supports the culture of home dialysis in NZ, and suggests that the extent and duration of survival benefit associated with early PD may be greater than appreciated. We are planning further analyses to exclude residual confounding from unmeasured co-morbidity and other sociodemographic factors using database linkage to NZ government datasets. Finally, our results suggest further research into the practice of PD in NZ Maori and Pacific People, as well as definitive study to determine the best timing for switching from PD in the late phase.

  19. Survival advantages of obesity in dialysis patients.

    Science.gov (United States)

    Kalantar-Zadeh, Kamyar; Abbott, Kevin C; Salahudeen, Abdulla K; Kilpatrick, Ryan D; Horwich, Tamara B

    2005-03-01

    In the general population, a high body mass index (BMI; in kg/m(2)) is associated with increased cardiovascular disease and all-cause mortality. However, the effect of overweight (BMI: 25-30) or obesity (BMI: >30) in patients with chronic kidney disease (CKD) undergoing maintenance hemodialysis (MHD) is paradoxically in the opposite direction; ie, a high BMI is associated with improved survival. Although this "reverse epidemiology" of obesity or dialysis-risk-paradox is relatively consistent in MHD patients, studies in CKD patients undergoing peritoneal dialysis have yielded mixed results. Growing confusion has developed among physicians, some of whom are no longer confident about whether to treat obesity in CKD patients. A similar reverse epidemiology of obesity has been described in geriatric populations and in patients with chronic heart failure (CHF). Possible causes of the reverse epidemiology of obesity include a more stable hemodynamic status, alterations in circulating cytokines, unique neurohormonal constellations, endotoxin-lipoprotein interaction, reverse causation, survival bias, time discrepancies among competitive risk factors, and malnutrition-inflammation complex syndrome. Reverse epidemiology may have significant clinical implications in the management of dialysis, CHF, and geriatric patients, ie, populations with extraordinarily high mortality. Exploring the causes and consequences of the reverse epidemiology of obesity in dialysis patients can enhance our insights into similar paradoxes observed for other conventional risk factors, such as blood pressure and serum cholesterol and homocysteine concentrations, and in other populations such as those with CHF, advanced age, cancer, or AIDS. Weight-gaining interventional studies in dialysis patients are urgently needed to ascertain whether they can improve survival and quality of life.

  20. Uncanny behaviour in survival horror games

    DEFF Research Database (Denmark)

    Tinwell, Angela; Grimshaw, Mark Nicholas; Williams, Andrew

    2010-01-01

    This study investigates the relationship between the perceived strangeness of a virtual character and the perception of human likeness for some attributes of motion and sound. Participants (N=100) were asked to rate thirteen video clips of twelve different virtual characters and one human. The re...... facial rendering and vocalization in survival horror games that can be used by game designers seeking to increase the fear factor in the genre, and that will form the basis of further experiments, which, it is hoped, will lead to a conceptual framework for the uncanny....

  1. Statin use and survival following glioblastoma multiforme

    DEFF Research Database (Denmark)

    Gaist, David; Hallas, Jesper; Friis, Søren

    2014-01-01

    AIM: While some studies indicate a potential chemopreventive effect of statin use on the risk of glioma, the effect of statins on the prognosis of brain tumours has not yet been examined. We thus conducted a cohort study evaluating the influence of statin use on survival in patients...... with glioblastoma multiforme (GBM). METHODS: We identified 1562 patients diagnosed with GBM during 2000-2009 from the Danish Cancer Registry and linked this cohort to Danish nationwide demographic and health registries. Within the GBM cohort, each patient recorded as using statins prior to diagnosis (defined as ≥2...... redeemed prescriptions) was matched to two statin non-users (

  2. BRAZILIAN EDUCATION AND SURVIVAL STRATEGIES OF CAPITALISM

    Directory of Open Access Journals (Sweden)

    Adriana Almeida Sales de Melo

    2012-06-01

    Full Text Available In discussing the theme Imperialism, Crisis and education, the essay points out aspects of our historical totality in relation to recent crises through which it passed capitalism, and its relationship to changes in Brazilian educational policies. Education remains at the heart of development projects, as a producer of knowledge, as well as guiding the processes of social conformation. They also discussed the aftermath of the crisis: the rise of social inequality and the increase of labor exploitation. Make clear our project of society and education, as resistance movements to the survival of capitalism is a necessity in building movements of counter-hegemony.

  3. [Dealing with competing events in survival analysis].

    Science.gov (United States)

    Béchade, Clémence; Lobbedez, Thierry

    2015-04-01

    Survival analyses focus on the occurrences of an event of interest, in order to determine risk factors and estimate a risk. Competing events prevent from observing the event of interest. If there are competing events, it can lead to a bias in the risk's estimation. The aim of this article is to explain why Cox model is not appropriate when there are competing events, and to present Fine and Gray model, which can help when dealing with competing risks. Copyright © 2015 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.

  4. The survival and return of institutions

    DEFF Research Database (Denmark)

    Guardiancich, Igor

    2011-01-01

    Opening a new phase in historical institutionalism, Wolfgang Streeck and Kathleen Thelen show how a rigid dichotomy between incremental adaptation and radical transformation fails to capture important transformative processes common to advanced political economies. While their research focuses......, where the old logic survives due to the redundancy of the new institutional arrangement; and reaction, where structural reforms generate demand for the old incentive structures, which are ultimately reintroduced. To elucidate the concepts, recent Croatian, Hungarian and Polish pension reforms...... are compared and their institutional instability analysed....

  5. "Unremarkable" recoveries: normalizing adversity and cancer survival.

    Science.gov (United States)

    Killoran, Moira; Schlitz, Marilyn Jean; Lewis, Nola

    2002-02-01

    Much of the existing popular literature suggests that survival from life-threatening diseases encourages a process of self-transformation. Seventeen long-term survivors of metastatic cancer were interviewed about the impact of a life-threatening condition on their life stories. Contrary to the existing literature, which suggests such an event greatly transforms the individual, nearly all of those interviewed for this study framed their unusual recoveries as being largely unremarkable. Traditional North American cultural values, which normalize adversity, appear to bolster the participants' beliefs that one can have control over one's health and can even resist a recurrence of cancer.

  6. Breast cancer survival and season of surgery

    DEFF Research Database (Denmark)

    Teilum, Dorthe; Bjerre, Karsten D; Tjønneland, Anne M

    2012-01-01

    Background Vitamin D has been suggested to influence the incidence and prognosis of breast cancer, and studies have found better overall survival (OS) after diagnosis for breast cancer in summer-autumn, where the vitamin D level are expected to be highest. Objective To compare the prognostic...... outcome for early breast cancer patients operated at different seasons of the year. Design Open population-based cohort study. Setting Danish women operated 1978-2010. Cases 79 658 adjusted for age at surgery, period of surgery, tumour size, axillary lymph node status and hormone receptor status...

  7. EVALUATION OF MICROBIAL SURVIVAL IN EXTRATERRESTRIAL ENVIRONMENTS

    Directory of Open Access Journals (Sweden)

    Betül BULUÇ

    2012-08-01

    Full Text Available In this paper, the space environments where microbial terrestrial life could form and evolve in, were evaluted with the base of the physical and chemical properties. In addition, Earthial microbial life formation conditions in the interstellar medium and the other planets are investigated and the survival of microorganisms in the space environments are questioned. As a result, considering the aspects of terrestrial microbial life, we suggest that the space environment and other planets could not be a habitat for Earthial microorganisms.

  8. Untold stories of Syrian women surviving war

    OpenAIRE

    Alhayek, Katty

    2015-01-01

    Issue title: Sympathetic stereotypes: the Syrian Uprising in western media and scholarship In "I must save my life and not risk my family’s safety!”: Untold Stories of Syrian Women Surviving War, Alhayek provides several case studies of Syrian women whose lives were irreversibly changed as a result of the events that unfolded after March 2011. The stories of these women vividly illustrate how difficult it is to come up with a neat and easily accessible profile for the suffering of Syrian w...

  9. Long-term survival in small-cell lung cancer

    DEFF Research Database (Denmark)

    Lassen, U; Osterlind, K; Hansen, M

    1995-01-01

    PURPOSE: To describe in patients with small-cell lung cancer (SCLC) the characteristics of those who survive for > or = 5 years, to identify long-term prognostic factors, to analyze survival data of 5-year survivors, and to study 10-year survival in patients entered before 1981. PATIENTS......, especially tobacco-related cancers and other tobacco-related diseases....

  10. 46 CFR 28.805 - Launching of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Launching of survival craft. 28.805 Section 28.805... FISHING INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.805 Launching of survival craft. In addition to the survival craft requirements in subpart B, each vessel must have a gate or other opening in the...

  11. 46 CFR 199.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 199.130 Section 199.130... LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS Requirements for All Vessels § 199.130 Stowage of survival craft. (a) General. Each survival craft must be stowed— (1) As close to the accommodation and service...

  12. 46 CFR 199.290 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 199.290 Section 199.290... of survival craft. (a) To meet the requirements of § 199.130(b)(1), each lifeboat— (1) On a cargo... required under § 199.261(e), no stowage position or muster and embarkation station for a survival craft on...

  13. 33 CFR 146.120 - Manning of survival craft.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Manning of survival craft. 146... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES OPERATIONS Manned OCS Facilities § 146.120 Manning of survival..., lifeboat, life raft, or survival capsule who shall be responsible for launching it in event of an emergency. ...

  14. 46 CFR 199.230 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 199.230 Section 199.230... Stowage of survival craft. (a) To meet the requirements of § 199.130(b)(1), each lifeboat on a passenger... height of a survival craft must take into account the vessel's escape provisions, the vessel's size, and...

  15. Biological aspects of genetic differences in piglet survival

    NARCIS (Netherlands)

    Leenhouwers, J.

    2001-01-01

    The objective of this thesis was to gain insight in the biological background of differences in the direct genetic (piglet) component of piglet survival. Estimations of the direct genetic component of piglet survival were obtained by calculation of estimated breeding values for piglet survival

  16. Genetic architecture of rainbow trout survival from egg to adult

    NARCIS (Netherlands)

    Vehvilainen, H.; Kause, A.; Quiton, C.; Kuukka-Anttila, H.; Koskinen, H.; Paananen, T.

    2010-01-01

    Survival from birth to a reproductive adult is a challenge that only robust individuals resistant to a variety of mortality factors will overcome. To assess whether survival traits share genetic architecture throughout the life cycle, we estimated genetic correlations for survival within fingerling

  17. In-hospital resuscitation: opioids and other factors influencing survival

    Directory of Open Access Journals (Sweden)

    Karamarie Fecho

    2009-12-01

    Full Text Available Karamarie Fecho1, Freeman Jackson1, Frances Smith1, Frank J Overdyk21Department of Anesthesiology, University of North Carolina, Chapel Hill, North Carolina, USA; 2Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, South Carolina, USAPurpose: “Code Blue” is a standard term used to alertt hospital staff that a patient requires resuscitation. This study determined rates of survival from Code Blue events and the role of opioids and other factors on survival.Methods: Data derived from medical records and the Code Blue and Pharmacy databases were analyzed for factors affecting survival.Results: During 2006, rates of survival from the code only and to discharge were 25.9% and 26.4%, respectively, for Code Blue events involving cardiopulmonary resuscitation (CPR; N = 216. Survival rates for events not ultimately requiring CPR (N = 77 were higher, with 32.5% surviving the code only and 62.3% surviving to discharge. For CPR events, rates of survival to discharge correlated inversely with time to chest compressions and defibrillation, precipitating event, need for airway management, location and age. Time of week, witnessing, postoperative status, gender and opioid use did not influence survival rates. For non-CPR events, opioid use was associated with decreased survival. Survival rates were lowest for patients receiving continuous infusions (P < 0.01 or iv boluses of opioids (P < 0.05.Conclusions: One-quarter of patients survive to discharge after a CPR Code Blue event and two-thirds survive to discharge after a non-CPR event. Opioids may influence survival from non-CPR events.Keywords: code blue, survival, opioids, cardiopulmonary resuscitation, cardiac arrest, patient safety

  18. Survival of microorganisms in space: a review.

    Science.gov (United States)

    Horneck, G

    1981-01-01

    Spores of Bacillus subtilis were exposed to selected factors of space (vacuum, solar UV radiation, heavy ions of cosmic radiation), and their response was studied after recovery. These investigations were supplemented by ground-based studies under simulated space conditions. The vacuum of space did not inactivate the spores. However, vacuum-induced structural changes in the DNA, and probably in the proteins, caused a supersensitivity to solar UV radiation. This phenomenon is caused by the production of specific photoproducts in DNA and protein, which cannot be removed by normal cellular repair processes. In vegetative bacterial cells, exposed to vacuum, cell dehydration led to damage of the cell membrane, which could be partly repaired during subsequent incubation. The high local effectiveness of the cosmic heavy ions further decreases the chance that spores can survive for any length of time in space. Nonetheless, a spore travelling through space and protected from ultraviolet radiation could possibly survive an interplanetary journey. Such a situation favors panspermia as a possible explanation for the origin of life.

  19. Animal reintroductions: an innovative assessment of survival

    Science.gov (United States)

    Muths, Erin L.; Bailey, Larissa L.; Watry, Mary Kay

    2014-01-01

    Quantitative evaluations of reintroductions are infrequent and assessments of milestones reached before a project is completed, or abandoned due to lack of funding, are rare. However, such assessments, which are promoted in adaptive management frameworks, are critical. Quantification can provide defensible estimates of biological success, such as the number of survivors from a released cohort, with associated cost per animal. It is unlikely that the global issues of endangered wildlife and population declines will abate, therefore, assurance colonies and reintroductions are likely to become more common. If such endeavors are to be successful biologically or achieve adequate funding, implementation must be more rigorous and accountable. We use a novel application of a multistate, robust design capture-recapture model to estimate survival of reintroduced tadpoles through metamorphosis (i.e., the number of individuals emerging from the pond) and thereby provide a quantitative measure of effort and success for an "in progress" reintroduction of toads. Our data also suggest that tadpoles released at later developmental stages have an increased probability of survival and that eggs laid in the wild hatched at higher rates than eggs laid by captive toads. We illustrate how an interim assessment can identify problems, highlight successes, and provide information for use in adjusting the effort or implementing a Decision-Theoretic adaptive management strategy.

  20. Lipid degradation promotes prostate cancer cell survival

    Science.gov (United States)

    Itkonen, Harri M; Brown, Michael; Urbanucci, Alfonso; Tredwell, Gregory; Lau, Chung Ho; Barfeld, Stefan; Hart, Claire; Guldvik, Ingrid J.; Takhar, Mandeep; Heemers, Hannelore V.; Erho, Nicholas; Bloch, Katarzyna; Davicioni, Elai; Derua, Rita; Waelkens, Etienne; Mohler, James L.; Clarke, Noel; Swinnen, Johan V.; Keun, Hector C.; Rekvig, Ole P.; Mills, Ian G.

    2017-01-01

    Prostate cancer is the most common male cancer and androgen receptor (AR) is the major driver of the disease. Here we show that Enoyl-CoA delta isomerase 2 (ECI2) is a novel AR-target that promotes prostate cancer cell survival. Increased ECI2 expression predicts mortality in prostate cancer patients (p = 0.0086). ECI2 encodes for an enzyme involved in lipid metabolism, and we use multiple metabolite profiling platforms and RNA-seq to show that inhibition of ECI2 expression leads to decreased glucose utilization, accumulation of fatty acids and down-regulation of cell cycle related genes. In normal cells, decrease in fatty acid degradation is compensated by increased consumption of glucose, and here we demonstrate that prostate cancer cells are not able to respond to decreased fatty acid degradation. Instead, prostate cancer cells activate incomplete autophagy, which is followed by activation of the cell death response. Finally, we identified a clinically approved compound, perhexiline, which inhibits fatty acid degradation, and replicates the major findings for ECI2 knockdown. This work shows that prostate cancer cells require lipid degradation for survival and identifies a small molecule inhibitor with therapeutic potential. PMID:28415728

  1. Synchronization and survival of connected bacterial populations

    Science.gov (United States)

    Gokhale, Shreyas; Conwill, Arolyn; Ranjan, Tanvi; Gore, Jeff

    Migration plays a vital role in controlling population dynamics of species occupying distinct habitat patches. While local populations are vulnerable to extinction due to demographic or environmental stochasticity, migration from neighboring habitat patches can rescue these populations through colonization of uninhabited regions. However, a large migratory flux can synchronize the population dynamics in connected patches, thereby enhancing the risk of global extinction during periods of depression in population size. Here, we investigate this trade-off between local rescue and global extinction experimentally using laboratory populations of E. coli bacteria. Our model system consists of co-cultures of ampicillin resistant and chloramphenicol resistant strains that form a cross-protection mutualism and exhibit period-3 oscillations in the relative population density in the presence of both antibiotics. We quantify the onset of synchronization of oscillations in a pair of co-cultures connected by migration and demonstrate that period-3 oscillations can be disturbed for moderate rates of migration. These features are consistent with simulations of a mechanistic model of antibiotic deactivation in our system. The simulations further predict that the probability of survival of connected populations in high concentrations of antibiotics is maximized at intermediate migration rates. We verify this prediction experimentally and show that survival is enhanced through a combination of disturbance of period-3 oscillations and stochastic re-colonization events.

  2. Acute pancreatitis: analysis of factors influencing survival.

    Science.gov (United States)

    Jacobs, M L; Daggett, W M; Civette, J M; Vasu, M A; Lawson, D W; Warshaw, A L; Nardi, G L; Bartlett, M K

    1977-01-01

    Of patients with acute pancreatitis (AP), there remains a group who suffer life-threatening complications despite current modes of therapy. To identify factors which distinguish this group from the entire patient population, a retrospectiva analysis of 519 cases of AP occurring over a 5-year period was undertaken. Thirty-one per cent of these patients had a history of alcoholism and 47% had a history of biliary disease. The overall mortality was 12.9%. Of symptoms and signs recorded at the time of admission, hypotension, tachycardia, fever, abdominal mass, and abnormal examination of the lung fields correlated positively with increased mortality. Seven features of the initial laboratory examination correlated with increased mortality. Shock, massive colloid requirement, hypocalcemia, renal failure, and respiratory failure requiring endotracheal intubation were complications associated with the poorest prognosis. Among patients in this series with three or more of these clinical characteristics, maximal nonoperative treatment yielded a survival rate of 29%, compared to the 64% survival rate for a group of patients treated operatively with cholecystostomy, gastrostomy, feeding jejunostomy, and sump drainage of the lesser sac and retroperitoneum.

  3. Deliberating over mastectomy: survival and social roles.

    Science.gov (United States)

    Fang, Su-Ying; Shu, Bih-Ching; Fetzer, Susan J

    2011-01-01

    Most studies based on a woman's decision regarding breast cancer treatments have focused on surgical treatment preference and related factors. Few studies have been carried out to identify the concerns associated with coming to terms with a mastectomy and cancer diagnosis among women eligible for a mastectomy only. The aim of this study was to explore Taiwanese women's experience about facing a mastectomy and to determine their deliberations before agreeing to a recommended mastectomy. Ten women who had undergone a mastectomy participated, with 3 undergoing individual interviews and 7 participating in a focus group. Findings during the interviews guided the focus group. Content analysis revealed 4 themes through the women's narratives of the decision-making experience when a mastectomy was recommended. These included (a) surviving is a priority, (b) fulfilling responsibility, (c) coming to terms with postsurgery alternatives, and (d) making arrangements. The experience surrounding the decision to undergo a mastectomy among Taiwanese women may be complicated by survival concerns, the meanings of the breast, and a feeling of an uncontrolled daily life. Cultural beliefs ensured that women were fulfilling their expected social roles and always thinking about significant others first. Recognizing women's private concerns with sensitivity and supporting women to balance their own needs and assigned social responsibilities are important considerations for women undergoing a mastectomy. Developing cultural competency is necessary for nurses working in communities with diverse ethnoculture people.

  4. Geothermal activity helps life survive glacial cycles.

    Science.gov (United States)

    Fraser, Ceridwen I; Terauds, Aleks; Smellie, John; Convey, Peter; Chown, Steven L

    2014-04-15

    Climate change has played a critical role in the evolution and structure of Earth's biodiversity. Geothermal activity, which can maintain ice-free terrain in glaciated regions, provides a tantalizing solution to the question of how diverse life can survive glaciations. No comprehensive assessment of this "geothermal glacial refugia" hypothesis has yet been undertaken, but Antarctica provides a unique setting for doing so. The continent has experienced repeated glaciations that most models indicate blanketed the continent in ice, yet many Antarctic species appear to have evolved in almost total isolation for millions of years, and hence must have persisted in situ throughout. How could terrestrial species have survived extreme glaciation events on the continent? Under a hypothesis of geothermal glacial refugia and subsequent recolonization of nongeothermal regions, we would expect to find greater contemporary diversity close to geothermal sites than in nongeothermal regions, and significant nestedness by distance of this diversity. We used spatial modeling approaches and the most comprehensive, validated terrestrial biodiversity dataset yet created for Antarctica to assess spatial patterns of diversity on the continent. Models clearly support our hypothesis, indicating that geothermally active regions have played a key role in structuring biodiversity patterns in Antarctica. These results provide critical insights into the evolutionary importance of geothermal refugia and the history of Antarctic species.

  5. Erythrocyte survival in sheep exposed to ozone

    Energy Technology Data Exchange (ETDEWEB)

    Moore, G.S.; Calabrese, E.J.; Labato, F.J.

    1981-07-01

    Erythrocyte survival studies in the Dorset ewe using chromium 51 were performed. The purpose of the study was to determine if ozone exposure produces decreased cell survival which may be the result of premature erythrocyte aging. This strain of sheep has an erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity that is very low, being comparable to human A-variants with G6PD deficiency. Ozone exposure may produce hemolytic effects in G6PD deficients more readily than in erythrocytes with normal activity. A decrease in hematocrit was observed in the ozone exposed groups. With respect to red cell destruction, ozone does not appear to act immediately, but rather there appears to be a delayed effect. At 0.25 ppM ozone, the group reached the 50% remaining level an average of 1 day sooner than the control group. There was no significant difference between control and exposed groups at the 0.50 ppM and 0.70 ppM levels. Also, the results demonstrate a net decrease in hematocrit which is greater for 0.25 ppM ozone than any other exposure level. (RJC)

  6. Survival of microorganisms in space: a review

    Energy Technology Data Exchange (ETDEWEB)

    Horneck, G.

    1981-01-01

    Spores of Bacillus subtilis were exposed to selected factors of space (vacuum, solar uv radiation, heavy cosmic ray ions), and their response was studied after recovery. These investigations were supplemented by ground-based studies under a simulated space conditions. The vacuum of space did not inactivate the spores. However, vacuum-induced structural changes in the DNA, and probably in the proteins, caused a supersensitivity to solar uv radiation. This phenomenon is caused by the production of specific photoproducts in DNA and protein, which cannot be removed by normal cellular repair processes. In vegetative bacterial cells exposed to vacuum, cell dehydration led to damage of the cell membrane, which could be partly repaired during subsequent incubation. The high local effectiveness of the heavy cosmic ray ions further decreases the chance that spores can survive for any length of time in space. Nonetheless, a spore travelling through space and protected from ultraviolet radiation could possibly survive an interplanetary journey. Such a situation favors panspermia as a possible explanation for the origin of life.

  7. Geothermal activity helps life survive glacial cycles

    Science.gov (United States)

    Fraser, Ceridwen I.; Terauds, Aleks; Smellie, John; Convey, Peter; Chown, Steven L.

    2014-01-01

    Climate change has played a critical role in the evolution and structure of Earth’s biodiversity. Geothermal activity, which can maintain ice-free terrain in glaciated regions, provides a tantalizing solution to the question of how diverse life can survive glaciations. No comprehensive assessment of this “geothermal glacial refugia” hypothesis has yet been undertaken, but Antarctica provides a unique setting for doing so. The continent has experienced repeated glaciations that most models indicate blanketed the continent in ice, yet many Antarctic species appear to have evolved in almost total isolation for millions of years, and hence must have persisted in situ throughout. How could terrestrial species have survived extreme glaciation events on the continent? Under a hypothesis of geothermal glacial refugia and subsequent recolonization of nongeothermal regions, we would expect to find greater contemporary diversity close to geothermal sites than in nongeothermal regions, and significant nestedness by distance of this diversity. We used spatial modeling approaches and the most comprehensive, validated terrestrial biodiversity dataset yet created for Antarctica to assess spatial patterns of diversity on the continent. Models clearly support our hypothesis, indicating that geothermally active regions have played a key role in structuring biodiversity patterns in Antarctica. These results provide critical insights into the evolutionary importance of geothermal refugia and the history of Antarctic species. PMID:24616489

  8. The dChip survival analysis module for microarray data

    Directory of Open Access Journals (Sweden)

    Minvielle Stéphane

    2011-03-01

    Full Text Available Abstract Background Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene expression based biomarkers in breast cancer. Similar predictions have recently been carried out using genome-wide copy number alterations and microRNAs. Existing software packages for microarray data analysis provide functions to define expression-based survival gene signatures. However, there is no software that can perform survival analysis using SNP array data or draw survival curves interactively for expression-based sample clusters. Results We have developed the survival analysis module in the dChip software that performs survival analysis across the genome for gene expression and copy number microarray data. Built on the current dChip software's microarray analysis functions such as chromosome display and clustering, the new survival functions include interactive exploring of Kaplan-Meier (K-M plots using expression or copy number data, computing survival p-values from the log-rank test and Cox models, and using permutation to identify significant chromosome regions associated with survival. Conclusions The dChip survival module provides user-friendly way to perform survival analysis and visualize the results in the context of genes and cytobands. It requires no coding expertise and only minimal learning curve for thousands of existing dChip users. The implementation in Visual C++ also enables fast computation. The software and demonstration data are freely available at http://dchip-surv.chenglilab.org.

  9. Democratic survival in Latin America (1945-2005

    Directory of Open Access Journals (Sweden)

    Aníbal PÉREZ-LIÑÁN

    2014-12-01

    Full Text Available Why do democracies survive or break down? In this paper, it returns to this classic question with an empirical focus on Latin America from 1945 to 2005. The argument deviates from the quantitative literature and a good part of the qualitative literature on democratic survival and breakdown. It is argued that structural variables such as the level of development and inequalities have not shaped prospects for democratic survival in Latin America. Nor, contrary to findings in some of the literature, has economic performance affected the survival of competitive regimes. Instead, it is focused on the regional political environment and on actors’ normative preferences about democracy and dictatorship and their policy radicalism or moderation. It is argued that 1 a higher level of development did not increase the likelihood of democratic survival in Latin America over this long time; 2 if actors have a normative preference for democracy, it is more likely to survive; and 3 policy moderation facilitates democratic survival.

  10. Strand V: Education for Survival. First Aid and Survival Education. Grades 4, 5, 6.

    Science.gov (United States)

    New York State Education Dept., Albany. Bureau of Elementary Curriculum Development.

    GRADES OR AGES: Grades 4-6. SUBJECT MATTER: First aid and survival education. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into seven sections: introduction to first aid; wounds and control of minor bleeding; respiratory emergencies and resuscitation; poisoning; traumatic shock; and injuries from abnormal conditions. The publication…

  11. Evaluating the use of enhanced oak seedlings for increased survival and growth: first-year survival

    Science.gov (United States)

    Joshua L. Moree; Andrew W. Ezell; John D. Hodges; Andrew J. Londo; K. David Godwin

    2010-01-01

    Oaks (Quercus spp.) are very important in the southern landscape for timber production and wildlife habitat. More landowners are attempting to establish oak plantations as the demand for wood products and wildlife habitat continues to increase. These attempts are not always successful with early growth and survival becoming major concerns. In this...

  12. Survival analysis of preweaning piglet survival in a dry-cured ham-producing crossbred line.

    Science.gov (United States)

    Cecchinato, A; Bonfatti, V; Gallo, L; Carnier, P

    2008-10-01

    The aim of this study was to investigate piglet preweaning survival and its relationship with a total merit index (TMI) used for selection of Large White terminal boars for dry-cured ham production. Data on 13,924 crossbred piglets (1,347 litters), originated by 189 Large White boars and 328 Large White-derived crossbred sows, were analyzed under a frailty proportional hazards model, assuming different baseline hazard functions and including sire and nursed litter as random effects. Estimated hazard ratios (HR) indicated that sex, cross-fostering, year-month of birth, parity of the nurse sow, size of the nursed litter, and class of TMI were significant effects for piglet preweaning survival. Female piglets had less risk of dying than males (HR = 0.81), as well as cross-fostered piglets (HR = 0.60). Survival increased when piglets were nursed by sows of third (HR = 0.85), fourth (HR = 0.76), and fifth (HR = 0.79) parity in comparison with first and second parity sows. Piglets of small (HR = 3.90) or very large litters (HR >1.60) had less chance of surviving in comparison with litters of intermediate size. Class of TMI exhibited an unfavorable relationship with survival (HR = 1.20 for the TMI top class). The modal estimates of sire variance under different baseline hazard functions were 0.06, whereas the variance for the nursed litter was close to 0.7. The estimate of the nursed litter effect variance was greater than that of the sire, which shows the importance of the common environment generated by the nurse sow. Relationships between sire rankings obtained from different survival models were high. The heritability estimate in equivalent scale was low and reached a value of 0.03. Nevertheless, the exploitable genetic variation for this trait justifies the inclusion of piglet preweaning survival in the current breeding program for selection of Large White terminal boars for dry-cured ham production.

  13. Survival of foodborne pathogens on inshell walnuts.

    Science.gov (United States)

    Blessington, Tyann; Theofel, Christopher G; Mitcham, Elizabeth J; Harris, Linda J

    2013-09-16

    The survival of Salmonella enterica Enteritidis PT 30 or five-strain cocktails of S. enterica, Escherichia coli O157:H7, and Listeria monocytogenes was evaluated on inshell walnuts during storage. Inshell walnuts were separately inoculated with an aqueous preparation of the pathogens at levels of 10 to 4 log CFU/nut, dried for 24 h, and then stored at either 4 °C or ambient conditions (23-25 °C, 25-35% relative humidity) for 3 weeks to more than 1 year. During the initial 24-h drying period, bacterial levels declined by 0.7 to 2.4 log CFU/nut. After the inoculum dried, further declines of approximately 0.1 log CFU/nut per month of Salmonella Enteritidis PT 30 levels were observed on inshell walnuts stored at 4 °C; at ambient conditions the rates of decline ranged from 0.55 to 2.5 log CFU/nut per month. Rates of decline were generally greater during the first few weeks of storage, particularly at lower inoculum levels. The survival of the five-strain cocktails inoculated at very low levels (under 400 CFU/nut) was determined during storage at ambient conditions. The pathogens could be recovered by either enumeration or enrichment from most samples throughout the 3-month storage period; reductions in bacterial levels from the beginning to end of storage were 0.7, 0.2, and 2.3 log CFU/nut for Salmonella, E. coli O157:H7, and L. monocytogenes, respectively. For 6% of all nut samples (14 of 234 samples), pathogens were isolated from the second but not first 24-h enrichment, suggesting that bacterial cells were viable but not easily culturable. Salmonella-inoculated walnuts were exposed for 2 min to water or a 3% solution of sodium hypochlorite (to mimic commercial brightening) either 24 h or 7 days after inoculation; treated nuts were dried for 24h and held at ambient conditions. Salmonella levels were reduced by less than 0.5 log or 2.4 to 2.6 log CFU/nut on water- or chlorine- treated walnuts, respectively, regardless of postinoculation treatment time. Additional

  14. Electrocardiographic abnormalities in centenarians: impact on survival

    Directory of Open Access Journals (Sweden)

    Rabuñal-Rey Ramón

    2012-04-01

    Full Text Available Abstract Background The centenarian population is gradually increasing, so it is becoming more common to see centenarians in clinical practice. Electrocardiogram abnormalities in the elderly have been reported, but several methodological biases have been detected that limit the validity of their results. The aim of this study is to analyse the ECG abnormalities in a prospective study of the centenarian population and to assess their impact on survival. Method We performed a domiciliary visit, where a medical history, an ECG and blood analysis were obtained. Barthel index (BI, cognitive mini-exam (CME and Charlson index (ChI were all determined. Patients were followed up by telephone up until their death. Results A total of 80 centenarians were studied, 26 men and 64 women, mean age 100.8 (SD 1.3. Of these, 81% had been admitted to the hospital at least once in the past, 81.3% were taking drugs (mean 3.3, rank 0–11. ChI was 1.21 (SD 1.19. Men had higher scores both for BI (70 -SD 34.4- vs. 50.4 -SD 36.6-, P = .005 and CME (16.5 -SD 9.1- vs. 9.1 –SD 11.6-, P = .008; 40.3% of the centenarians had anaemia, 67.5% renal failure, 13% hyperglycaemia, 22.1% hypoalbuminaemia and 10.7% dyslipidaemia, without statistically significant differences regarding sex. Only 7% had a normal ECG; 21 (26.3% had atrial fibrillation (AF, 30 (37.5% conduction defects and 31 (38.8% abnormalities suggestive of ischemia, without sex-related differences. A history of heart disease was significantly associated with the presence of AF (P = .002, OR 5.2, CI 95% 1.8 to 15.2 and changes suggestive of ischemia (P = .019, OR 3.2, CI 95% 1.2-8.7. Mean survival was 628 days (SD 578.5, median 481 days. Mortality risk was independently associated with the presence of AF (RR 2.0, P = .011, hyperglycaemia (RR 2.2, P = .032, hypoalbuminaemia (RR 3.5, P P = .024. Conclusion Although ECG abnormalities are common in centenarians, they are not related to

  15. Reproduction, preweaning survival, and survival of adult sea otters at Kodiak Island, Alaska

    Science.gov (United States)

    Monson, Daniel H.; DeGange, Anthony R.

    1995-01-01

    Radiotelemetry methods were used to examine the demographic characteristics of sea otters inhabiting the leading edge of an expanding population on Kodiak Island, Alaska. Fifteen male and 30 female sea otters were instrumented and followed from 1986 to 1990. Twenty-one percent of females were sexually mature (had pupped) at age 2, 57% by age 3, 88% by age 4, and 100% by age 5. Fifteen females produced 26 pups, an overall reproduction rate of 94% for mature females. The reproduction rate was 17, 45, 66, and 100% for 2-, 3-, 4-, and 5-year-olds, respectively. Eighty-five percent of observed pups survived to weaning (120 days), and the percentage of pups weaned ranged from 34% for pups of 2-year-olds to 100% for pups of 5-year-olds. At least three of four known pup losses occurred within a month of parturition. The mean pup dependency period for weaned pups was 153 days and the mean gestation period was 218 days. No synchrony in pupping activity was observed. Mean annual survival of adults was high. Estimates of survival ranged from 89 to 96% for females and 86 to 91% for males. Human harvest was the primary source of known mortality of adults. Our estimates of reproductive rates and survival of adults are at the high end of those reported for sea otters, but preweaning survival stands out as being particularly high. Abundant food resources and the availability of protected water presumably contributed to the high reproductive success observed in this recently established sea otter population.

  16. Early survival factor deprivation in the olfactory epithelium enhances activity-dependent survival

    Directory of Open Access Journals (Sweden)

    Adrien eFrançois

    2013-12-01

    Full Text Available The neuronal olfactory epithelium undergoes permanent renewal because of environmental aggression. This renewal is partly regulated by factors modulating the level of neuronal apoptosis. Among them, we had previously characterized endothelin as neuroprotective. In this study, we explored the effect of cell survival factor deprivation in the olfactory epithelium by intranasal delivery of endothelin receptors antagonists to rat pups. This treatment induced an overall increase of apoptosis in the olfactory epithelium. The responses to odorants recorded by electroolfactogram were decreased in treated animal, a result consistent with a loss of olfactory sensory neurons (OSNs. However, the treated animal performed better in an olfactory orientation test based on maternal odor compared to non-treated littermates. This improved performance could be due to activity-dependent neuronal survival of OSNs in the context of increased apoptosis level. In order to demonstrate it, we odorized pups with octanal, a known ligand for the rI7 olfactory receptor (Olr226. We quantified the number of OSN expressing rI7 by RT-qPCR and whole mount in situ hybridization. While this number was reduced by the survival factor removal treatment, this reduction was abolished by the presence of its ligand. This improved survival was optimal for low concentration of odorant and was specific for rI7-expressing OSNs. Meanwhile, the number of rI7-expressing OSNs was not affected by the odorization in non-treated littermates; showing that the activity-dependant survival of OSNs did not affect the OSN population during the 10 days of odorization in control conditions. Overall, our study shows that when apoptosis is promoted in the olfactory mucosa, the activity-dependent neuronal plasticity allows faster tuning of the olfactory sensory neuron population towards detection of environmental odorants.

  17. Early survival factor deprivation in the olfactory epithelium enhances activity-driven survival

    Science.gov (United States)

    François, Adrien; Laziz, Iman; Rimbaud, Stéphanie; Grebert, Denise; Durieux, Didier; Pajot-Augy, Edith; Meunier, Nicolas

    2013-01-01

    The neuronal olfactory epithelium undergoes permanent renewal because of environmental aggression. This renewal is partly regulated by factors modulating the level of neuronal apoptosis. Among them, we had previously characterized endothelin as neuroprotective. In this study, we explored the effect of cell survival factor deprivation in the olfactory epithelium by intranasal delivery of endothelin receptors antagonists to rat pups. This treatment induced an overall increase of apoptosis in the olfactory epithelium. The responses to odorants recorded by electroolfactogram were decreased in treated animal, a result consistent with a loss of olfactory sensory neurons (OSNs). However, the treated animal performed better in an olfactory orientation test based on maternal odor compared to non-treated littermates. This improved performance could be due to activity-dependent neuronal survival of OSNs in the context of increased apoptosis level. In order to demonstrate it, we odorized pups with octanal, a known ligand for the rI7 olfactory receptor (Olr226). We quantified the number of OSN expressing rI7 by RT-qPCR and whole mount in situ hybridization. While this number was reduced by the survival factor removal treatment, this reduction was abolished by the presence of its ligand. This improved survival was optimal for low concentration of odorant and was specific for rI7-expressing OSNs. Meanwhile, the number of rI7-expressing OSNs was not affected by the odorization in non-treated littermates; showing that the activity-dependant survival of OSNs did not affect the OSN population during the 10 days of odorization in control conditions. Overall, our study shows that when apoptosis is promoted in the olfactory mucosa, the activity-dependent neuronal plasticity allows faster tuning of the olfactory sensory neuron population toward detection of environmental odorants. PMID:24399931

  18. Diversification patterns and survival as firms mature

    DEFF Research Database (Denmark)

    Coad, Alexander Jean-Luc; Guenther, C.

    2013-01-01

    into new submarkets). Our analysis reveals four main insights. First, we observe that firms have lower diversification rates as they grow older, and that eventually diversification rates even turn negative for old firms on average (where negative diversification corresponds to exit from certain product......We focus on the relationship between age and diversification patterns of German machine tool manufacturers in the post-war era. We distinguish between 'minor diversification' (adding a new product variation within a familiar submarket) and 'major diversification' (expanding the product portfolio....... Fourth, survival estimations reveal that diversification activities reduce the risk of exit in general and to a varying degree at different ages. These results are interpreted using Penrosean growth theory....

  19. Hypothalamic survival circuits: blueprints for purposive behaviors.

    Science.gov (United States)

    Sternson, Scott M

    2013-03-06

    Neural processes that direct an animal's actions toward environmental goals are critical elements for understanding behavior. The hypothalamus is closely associated with motivated behaviors required for survival and reproduction. Intense feeding, drinking, aggressive, and sexual behaviors can be produced by a simple neuronal stimulus applied to discrete hypothalamic regions. What can these "evoked behaviors" teach us about the neural processes that determine behavioral intent and intensity? Small populations of neurons sufficient to evoke a complex motivated behavior may be used as entry points to identify circuits that energize and direct behavior to specific goals. Here, I review recent applications of molecular genetic, optogenetic, and pharmacogenetic approaches that overcome previous limitations for analyzing anatomically complex hypothalamic circuits and their interactions with the rest of the brain. These new tools have the potential to bridge the gaps between neurobiological and psychological thinking about the mechanisms of complex motivated behavior. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Succession and survival in psychotherapy organizations.

    Science.gov (United States)

    Khaleelee, Olya

    2008-11-01

    This paper examines the world of psychotherapy by applying a systemic and psychodynamic understanding of the family business as a way of understanding the dilemmas and challenges of leadership succession. Oedipal factors are explored as an important theme within the succession process. This exploration is set within the context of what function psychotherapy has performed in society over the last thirty years. The hypothesis is that the first generation of leaders aimed to provide containment for the individual citizen at a time of failed dependency in society. The suggestion is that this gave way to the primary task for the second generation, which has been to focus on the therapist in training. The challenge for the third generation is to develop a meaningful role for psychotherapy today and to ensure survival at a time when other shorter therapies such as CBT are gaining ascendancy over longer term psychoanalytic psychotherapy.

  1. Universal doomsday: analyzing our prospects for survival

    Energy Technology Data Exchange (ETDEWEB)

    Gerig, Austin [CABDyN Complexity Centre, Saïd Business School, University of Oxford, Oxford OX1 1HP (United Kingdom); Olum, Ken D.; Vilenkin, Alexander, E-mail: austin.gerig@sbs.ox.ac.uk, E-mail: kdo@cosmos.phy.tufts.edu, E-mail: vilenkin@cosmos.phy.tufts.edu [Institute of Cosmology, Department of Physics and Astronomy, Tufts University, Medford MA 02155 (United States)

    2013-05-01

    Given a sufficiently large universe, numerous civilizations almost surely exist. Some of these civilizations will be short-lived and die out relatively early in their development, i.e., before having the chance to spread to other planets. Others will be long-lived, potentially colonizing their galaxy and becoming enormous in size. What fraction of civilizations in the universe are long-lived? The ''universal doomsday'' argument states that long-lived civilizations must be rare because if they were not, we should find ourselves living in one. Furthermore, because long-lived civilizations are rare, our civilization's prospects for long-term survival are poor. Here, we develop the formalism required for universal doomsday calculations and show that while the argument has some force, our future is not as gloomy as the traditional doomsday argument would suggest, at least when the number of early existential threats is small.

  2. Surviving Impact in Experiments and on Planets

    Science.gov (United States)

    Schultz, P. H.

    2012-12-01

    Oblique impacts experiments in the laboratory (at the NASA Ames Vertical Gun Range, AVGR) reveal that significant fractions of the projectile can survive impact for impact speeds of 6km/s and contribute to the cratering process or remain preserved within or around the crater. At low impact angles (30° from the horizontal) into strength-controlled targets (aluminum, copper), survivors re-impact witness plates downrange with fragments as large as 10% of the initial mass surviving intact. Scouring by projectile fragments during penetration contributes to many of the crater floor structures in strength-controlled targets, e.g., as erosion pits and downrange shelf. Frozen flow lines in ductile targets reveal the center of maximum coupling, well above the crater floor on the uprange wall. Above this zone, small projectile fragments survive on the uprange wall (even at high impact angles), whereas impactor-melt coats the crater floor downrange. Beyond the crater rim downrange, melt from the impactor scours the surface and coats the surface. Hydrocode models capture some of these processes at both small and large scales (e.g., downrange bench within the crater and downrange melt sliding along the surface), but they do not capture the fine-scale detailed interactions. Such laboratory impact experiments reveal fundamental processes typically ignored when interpreting planetary-scale collisions. For example, decapitated portions of the impactor from oblique impacts excavate portions of the surface downrange prior to the excavation stage. As a result, the transient crater does not grow across a flat surface but intersects a depression downrange created by the failed impactor. This affects crater excavation, ejecta evolution, and dispersal of impactor signatures. While laboratory impact velocities (6km/s) do not approach many planetary-scale applications (20km/s), oblique impacts result in peak pressures comparable to laboratory conditions, especially on Mars or the lower

  3. Cardiac transplantation. Selection, immunosuppression, and survival.

    Science.gov (United States)

    Stevenson, L W; Laks, H; Terasaki, P I; Kahan, B D; Drinkwater, D C

    1988-01-01

    Cardiac transplantation has evolved from an experiment to an accepted therapy for severe heart failure. Increasing competition for donor organs mandates a greater emphasis on selection and timing for transplantation and paradoxically forces more reliance on aggressive medical therapy for all patients after evaluation. The growth of recipient and donor pools may enhance the opportunity for assessing histocompatibility, for which distinguishing between autoantibodies and human leukocyte antigen-determined reactivity is important, and some general nonresponders may be detected. Therapy with cyclosporine has improved the outcome after transplantation, but further refinement is needed, perhaps with pharmacologic synergy, to minimize nephrotoxicity and maximize specific immunosuppression. Survival is more than 80% at 1 year, after which the incidence of acute rejection and infection declines and accelerated atherosclerosis becomes prominent. Although resuming employment is not always possible, the overall quality of life is excellent after cardiac transplantation. Images PMID:3074557

  4. Neonatal appendicitis: a survival case study

    Directory of Open Access Journals (Sweden)

    Izabela Linha Secco

    Full Text Available ABSTRACT Objective: To report a case of neonatal appendicitis in a children’s hospital in southern Brazil, demonstrating the impact on neonatal survival. Method: Case study with data collection from medical records, approved by the Institution and Ethics Committee for Research with Human Beings. Results: The clinical picture is initially characterized by food intolerance, evolving to hypoactivity, alteration of vital signs and septicemia due to intestinal perforation. Management is exclusively surgical, since no case described in the literature was diagnosed preoperatively and the findings usually point to acute abdomen. Conclusion: A focused clinical surveillance should be established when the infant presents peritoneal irritation. Follow-up of the evolution and the worsening of the symptoms by nurses, as part of the care team in partnership with the medical team, enables an early surgical intervention, thereby avoiding complications such as septicemia and death.

  5. Foreign acquisition, plant survival, and employment growth

    DEFF Research Database (Denmark)

    Bandick, Roger; Görg, Holger

    This paper analyses the effect of foreign acquisition on survival probability and employment growth of target plant using data on Swedish manufacturing plants during the period 1993-2002.  An improvement over previous studies is that we take into account firm level heterogeneity by separating...... the lifetime of the acquired plants only if the plant was an exporter.  The effect differs depending on whether the acquisition is horizontal or vertical.  We also find robust positive employment growth effects only for exporters, and only if the takeover is vertical, not horizontal....... the targeted plants into those within Swedish MNEs, Swedish exporting non-MNEs, and purely domestic firms before foreign takeover. The results, controlling for possible endogeneity of the acquisition dummy using an IV and propensity score matching approach suggest that acquisition by foreign owners increases...

  6. Apes in the Anthropocene: flexibility and survival.

    Science.gov (United States)

    Hockings, Kimberley J; McLennan, Matthew R; Carvalho, Susana; Ancrenaz, Marc; Bobe, René; Byrne, Richard W; Dunbar, Robin I M; Matsuzawa, Tetsuro; McGrew, William C; Williamson, Elizabeth A; Wilson, Michael L; Wood, Bernard; Wrangham, Richard W; Hill, Catherine M

    2015-04-01

    We are in a new epoch, the Anthropocene, and research into our closest living relatives, the great apes, must keep pace with the rate that our species is driving change. While a goal of many studies is to understand how great apes behave in natural contexts, the impact of human activities must increasingly be taken into account. This is both a challenge and an opportunity, which can importantly inform research in three diverse fields: cognition, human evolution, and conservation. No long-term great ape research site is wholly unaffected by human influence, but research at those that are especially affected by human activity is particularly important for ensuring that our great ape kin survive the Anthropocene. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. HTC: May survive in bipolar world

    Directory of Open Access Journals (Sweden)

    Singh Netra Pal

    2016-01-01

    Full Text Available The core assets of HTC are people, innovations, and technology. But in the recent quarters, HTC has started retrenching people even from R&D divisions which are responsible for innovation and developing new technologies. It means HTC's core assets are depleting. HTC was known for its cutting edge technology of 16mp camera and high speed '4G' technology but performing badly in the last two and half year. Why is it so? Paper objectives are to identify reasons for its downfall of HTC, distress signals for HTC downfall, and possible revival strategies for survival of HTC in Bipolar world (Samsung and Apple of smartphones makers. In addition, research paper present eight research proposition/ questions with respect to present state of HTC and its future and possible answers to these research propositions/ questions. Research paper ends with concluding remarks in the context of HTC future.

  8. Survival and activity of individual bioaugmentation strains

    DEFF Research Database (Denmark)

    Dueholm, Morten Simonsen; G. Marquesa, Irina; Karst, Søren Michael

    2015-01-01

    Successful application of bioaugmentation for enhanced degradation of environmental pollutants is often limited by the lack of methods to monitor the survival and activity of individual bioaugmentation strains. However, recent advancements in sequencing technologies and molecular techniques now...... allow us to address these limitations. Here a complementing set of general applicable molecular methods are presented that provides detailed information on the performance of individual bioaugmentation strains under in situ conditions. The approach involves genome sequencing to establish highly specific...... qPCR and RT-qPCR tools for cell enumerations and expression of involved genes, stable isotope probing to follow growth on the target compounds and GFP-tagging to visualize the bioaugmentation strains directly in samples, all in combination with removal studies of the target compounds. The concept...

  9. Survival and personal identity in orphism

    Directory of Open Access Journals (Sweden)

    Carlos Megino Rodríguez

    2016-10-01

    Full Text Available The aim of the article is to clarify the conditions which are fulfilled by the soul in orphism in order to base on it the possibility of self-survival. To this end, we study what the soul consists of in orphism, analyzing all orphic testimonies that allow us to draw conclusions in connection with the role of the soul in the orphic conception of personal identity. We also take into account the role played by other factors in orphism, like the body and memory, as possible criteria for personal identity. Finally, we conclude that the soul in orphism is the bearer of the personal identity, because it is a substantive, individual and independent entity, of a unique and permanent nature, immortal and the subject of a unique and untransferable vital history.

  10. [A clinical predictor index for renal survival].

    Science.gov (United States)

    Araújo, Nordeval Cavalcante; Rioja, Lilimar da Silveira; Rebelo, Maria Alice Puga

    2010-03-01

    A clinical index that discriminates disease progression independent of histopathologic features may be valuable in the best timing of biopsy. This study addresses the question if a clinical index based on cortical echogenicity, renal length to body height ratio (KL/H), and serum creatinine levels predicts renal survival. The study enrolled 154 patients. Biopsy specimens were graded for chronic (glomerular obsolescence, segmental glomerular sclerosis, tubular atrophy and interstitial fibrosis) and acute (mesangial proliferation, leucocyte permeation, crescent and fibrinoid necrosis and interstital infiltrate) index by the sum of scored lesions. A chronic clinical index was created by the sum of scored cortical echogenicity relative to liver or spleen, creatinine serum levels and KL/H. The study end point was start on dialisis. Higher grade of chronic clinical and biopsy indices were associated with poorer long-term renal survival. Five out of six patients with serum creatinine levels > 2.5mg/dL, highest cortical echogenicity and KL/H < 0.60, before biopsy, started on dialysis and one increased creatinine levels up to 4.5 mg/dL. The chronic clinical index correlates well with chronic biopsy index. The chronic clinical index could be useful to predict a clinical setting in which a renal biopsy will show advanced chronic and irreversible lesion. In patients with highest grade of clinical parameters renal biopsy can be obviate. As a chronicity of illness index for groups of patients with renal medical diseases, the system could be useful in outcome comparisons and evaluation of therapeutic efficacy.

  11. Thyroid function and survival following breast cancer.

    Science.gov (United States)

    Brandt, J; Borgquist, S; Almquist, M; Manjer, J

    2016-11-01

    Thyroid function has been associated with breast cancer risk, and breast cancer cell growth and proliferation. It is not clear whether thyroid function affects prognosis following breast cancer but, if so, this could have an important clinical impact. The present study analysed prospectively collected measurements of free tri-iodothyronine (T3), free thyroxine (T4), thyroid-stimulating hormone (TSH) and thyroid peroxidase antibodies (TPO-Ab) in relation to breast cancer survival. The Malmö Diet and Cancer Study is a prospective cohort study of 17 035 women in Sweden. Study enrolment was conducted between 1991 and 1996. Patients with incident breast cancer were identified through record linkage with cancer registries until 31 December 2006. Information on vital status was collected from the Swedish Cause of Death Registry, with the endpoint breast cancer mortality (31 December 2013). Hazard ratios (HRs) with 95 per cent confidence intervals (c.i.) were obtained by Cox proportional hazards analysis. Some 766 patients with incident breast cancer were identified, of whom 551 were eligible for analysis. Compared with patients in the first free T4 tertile, breast cancer mortality was lower among those in the second tertile (HR 0·49, 95 per cent c.i. 0·28 to 0·84). There was an indication, although non-significant, of lower breast cancer mortality among patients in the second TSH tertile (HR 0·63, 0·37 to 1·09) and in those with positive TPO-Ab status (HR 0·61, 0·30 to 1·23). Free T3 showed no clear association with mortality. In the present study, there was a positive association between free T4 levels and improved breast cancer survival. © 2016 BJS Society Ltd Published by John Wiley & Sons Ltd.

  12. Early diagnosis improves survival in kidney cancer.

    Science.gov (United States)

    Lewis, Gareth; Maxwell, Alexander P

    2012-02-01

    Kidney cancers account for 2-3% of all adult malignancies in the UK. Men are predominantly affected by renal cancer with an average age at diagnosis of 64 years. Renal (or clear) cell carcinoma (RCC) accounts for 90% of kidney cancers. Early diagnosis improves survival with five-year survival rates for renal cancer of 70-94% for localised tumours in the UK. RCC should be suspected in the presence of localising symptoms such as flank pain, a loin mass or haematuria; constitutional upset including weight loss, pyrexia and/or night sweats; or with unexplained laboratory tests. Smoking, obesity and hypertension are the most important and most common risk factors. Environmental exposure to asbestos, cadmium and trichloroethylene are less common risk factors. Patients on chronic dialysis and renal transplant recipients are at increased risk of RCC in their native kidneys. If kidney cancer is suspected on history, physical examination or initial screening tests then a red flag ultrasound examination of the renal tracts should be requested. Dipstick urinalysis is of great value as asymptomatic haematuria may be the only abnormal test in the presence of non-specific symptoms such as weight loss or loin pain. Visible or non-visible haematuria, in the absence of proteinuria, suggests an underlying structural abnormality is present in the kidneys, ureters or bladder. Surgical removal of RCCs, where feasible, may result in cure in up to 40-60% of cases. Individuals too frail for major surgery may benefit from thermal ablation and cryotherapy. Agents that target the VEGF and mTOR pathways are considered first line in the treatment of metastatic RCC. Sunitinib, recommended by NICE, is administered orally and acts by inhibiting the VEGF receptor.

  13. SERCA control of cell death and survival.

    Science.gov (United States)

    Chemaly, Elie R; Troncone, Luca; Lebeche, Djamel

    2018-01-01

    Intracellular calcium (Ca2+) is a critical coordinator of various aspects of cellular physiology. It is increasingly apparent that changes in cellular Ca2+ dynamics contribute to the regulation of normal and pathological signal transduction that controls cell growth and survival. Aberrant perturbations in Ca2+ homeostasis have been implicated in a range of pathological conditions, such as cardiovascular diseases, diabetes, tumorigenesis and steatosis hepatitis. Intracellular Ca2+ concentrations are therefore tightly regulated by a number of Ca2+ handling enzymes, proteins, channels and transporters located in the plasma membrane and in Ca2+ storage organelles, which work in concert to fine tune a temporally and spatially precise Ca2+ signal. Chief amongst them is the sarco/endoplasmic reticulum (SR/ER) Ca2+ ATPase pump (SERCA) which actively re-accumulates released Ca2+ back into the SR/ER, therefore maintaining Ca2+ homeostasis. There are at least 14 different SERCA isoforms encoded by three ATP2A1-3 genes whose expressions are species- and tissue-specific. Altered SERCA expression and activity results in cellular malignancy and induction of ER stress and ER stress-associated apoptosis. The role of SERCA misregulation in the control of apoptosis in various cell types and disease setting with prospective therapeutic implications is the focus of this review. Ca2+ is a double edge sword for both life as well as death, and current experimental evidence supports a model in which Ca2+ homeostasis and SERCA activity represent a nodal point that controls cell survival. Pharmacological or genetic targeting of this axis constitutes an incredible therapeutic potential to treat different diseases sharing similar biological disorders. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Survival and Prognosis for Malignant Tumors of Odontogenic Origin.

    Science.gov (United States)

    Agarwal, Sunil; Mark, Jonathan; Xie, Changchun; Ghulam, Enas; Patil, Yash

    2016-07-01

    Determine survival and factors affecting survival for patients with malignant tumors of odontogenic origin. Retrospective analysis of the National Cancer Institute's SEER database (Surveillance, Epidemiology, and End Results). Tertiary medical center. All cases of malignant tumors of odontogenic origin were extracted from the SEER database for the period of 1973 to 2011. Demographic, tumor-specific, and survival data were tabulated and Kaplan-Meier survival analysis conducted according to histopathologic results. Cox regression analysis stratified for histopathology was conducted to determine factors that influenced survival. A total of 308 cases of malignant tumors with odontogenic origin were analyzed. Malignant ameloblastoma accounted for 59.7% of cases, followed by malignant odontogenic tumor (35.4%; including odontogenic carcinoma, odontogenic sarcoma, primary intraosseous carcinoma, and ameloblastic carcinoma) and ameloblastic fibrosarcoma (2.9%). The overall mean and median were 229 and 227 months, respectively, while the 5-year survival rate was 81% for the entire cohort. Malignant ameloblastoma exhibited the best mean survival (237 months), whereas malignant odontogenic tumor (139 months) and ameloblastic fibrosarcoma (42 months) had lower mean survival rates. Younger age, surgery with adjuvant radiation, and smaller tumor size were found to improve survival. Significantly different survival can be expected depending on individual tumor histopathology, tumor size, age at diagnosis, and treatment modality. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2016.

  15. Survival of adult female northern pintails in Sacramento Valley, California

    Science.gov (United States)

    Miller, Michael R.; Fleskes, Joseph P.; Orthmeyer, Dennis L.; Newton, Wesley E.; Gilmer, David S.

    1995-01-01

    North American populations of northern pintails (Anas acuta) declined between 1979 and the early 1990s. To determine if low survival during winter contributed to declines, we estimated winter (last week of Aug-Feb 1987-90) survival for 190 adult (after hatching yr [AHY]) female radio-tagged pintails in late summer in Sacramento Valley (SACV), California. Survival rates did not vary by winter (P = 0.808), among preseason, hunting season, or postseason intervals (P = 0.579), or by body mass at time of capture (P = 0.127). Premolt (wing) pintails (n = 10) tended to survive at a lower rate (0.622, SE = 0.178) than pintails that had already replaced flight feathers (0.887, SE = 0.030) (P = 0.091). The pooled survival (all years) estimate for the 180-day winter was 0.874 (SE = 0.031). Hunting mortality rate (0.041-0.087) and nonhunting mortality rate (0.013-0.076) did not differ among years (P = 0.332) or within years (all P > 0.149). Legal hunting (n = 7), predation (n = 4), cholera (n = 2), illegal shooting (n = 2), botulism (n = 1), and unknown cause (n = 1) accounted for all mortality. Nonwintering survival (annu. survival/winter survival = 0.748) was lower than winter survival; thus, if gains in annual survival are desired for this population, managers should first examine the breeding-migration period for opportunities to achieve increases.

  16. Chronic consequences of acute injuries: worse survival after discharge.

    Science.gov (United States)

    Shafi, Shahid; Renfro, Lindsay A; Barnes, Sunni; Rayan, Nadine; Gentilello, Larry M; Fleming, Neil; Ballard, David

    2012-09-01

    The Trauma Quality Improvement Program uses inhospital mortality to measure quality of care, which assumes patients who survive injury are not likely to suffer higher mortality after discharge. We hypothesized that survival rates in trauma patients who survive to discharge remain stable afterward. Patients treated at an urban Level I trauma center (2006-2008) were linked with the Social Security Administration Death Master File. Survival rates were measured at 30, 90, and 180 days and 1 and 2 years from injury among two groups of trauma patients who survived to discharge: major trauma (Abbreviated Injury Scale score ≥ 3 injuries, n = 2,238) and minor trauma (Abbreviated Injury Scale score ≤ 2 injuries, n = 1,171). Control groups matched to each trauma group by age and sex were simulated from the US general population using annual survival probabilities from census data. Kaplan-Meier and log-rank analyses conditional upon survival to each time point were used to determine changes in risk of mortality after discharge. Cox proportional hazards models with left truncation at the time of discharge were used to determine independent predictors of mortality after discharge. The survival rate in trauma patients with major injuries was 92% at 30 days posttrauma and declined to 84% by 3 years (p > 0.05 compared with general population). Minor trauma patients experienced a survival rate similar to the general population. Age and injury severity were the only independent predictors of long-term mortality given survival to discharge. Log-rank tests conditional on survival to each time point showed that mortality risk in patients with major injuries remained significantly higher than the general population for up to 6 months after injury. The survival rate of trauma patients with major injuries remains significantly lower than survival for minor trauma patients and the general population for several months postdischarge. Surveillance for early identification and treatment of

  17. Survival and clinical outcome of dogs with ischaemic stroke

    DEFF Research Database (Denmark)

    Gredal, Hanne Birgit; Toft, Nils; Westrup, Ulrik

    2013-01-01

    The objectives of the present study were to investigate survival time, possible predictors of survival and clinical outcome in dogs with ischaemic stroke. A retrospective study of dogs with a previous diagnosis of ischaemic stroke diagnosed by magnetic resonance imaging (MRI) was performed....... The association between survival and the hypothesised risk factors was examined using univariable exact logistic regression. Survival was examined using Kaplan-Meier and Cox regression. Twenty-two dogs were identified. Five dogs (23%) died within the first 30days of the stroke event. Median survival in 30-day...... survivors was 505days. Four dogs (18%) were still alive by the end of the study. Right-sided lesions posed a significantly increased risk of mortality with a median survival time in dogs with right-sided lesions of 24days vs. 602days in dogs with left sided lesions (P=0.006). Clinical outcome was considered...

  18. Clay mineral type effect on bacterial enteropathogen survival in soil.

    Science.gov (United States)

    Brennan, Fiona P; Moynihan, Emma; Griffiths, Bryan S; Hillier, Stephen; Owen, Jason; Pendlowski, Helen; Avery, Lisa M

    2014-01-15

    Enteropathogens released into the environment can represent a serious risk to public health. Soil clay content has long been known to have an important effect on enteropathogen survival in soil, generally enhancing survival. However, clay mineral composition in soils varies, and different clay minerals have specific physiochemical properties that would be expected to impact differentially on survival. This work investigated the effect of clay materials, with a predominance of a particular mineral type (montmorillonite, kaolinite, or illite), on the survival in soil microcosms over 96 days of Listeria monocytogenes, Salmonella Dublin, and Escherichia coli O157. Clay mineral addition was found to alter a number of physicochemical parameters in soil, including cation exchange capacity and surface area, and this was specific to the mineral type. Clay mineral addition enhanced enteropathogen survival in soil. The type of clay mineral was found to differentially affect enteropathogen survival and the effect was enteropathogen-specific. © 2013.

  19. Bacterial survival responses to extreme desiccation and high humidity

    Science.gov (United States)

    Yang, Yinjie; Yokobori, Shinichi; Yamagishi, Akihiko

    The presence of water is thought to be essential for life and strongly considered in life searching operation on extraterrestrial planets. In this study we show different survival responses of bacterial species to water availability and temperatures (25, 4 and - 70 o C). At these temperatures, E.coli lost viability much faster under extreme desiccation than under high humidity. Deinococcus radiodurans exhibited much higher survival rate under desiccation than under high humidity at 25 o C, while its survivals under desiccation and high humidity increased to the same level at 4 and - 70 o C. Bacillus pumilus spores generally survived well under all tested conditions. Water is favorable for the survival of most microorganisms but not a "safeguard" for all microorganisms. Microbial survival at low temperatures may not be affected by water availability. Water absence should not preclude us from seeking life on other planets.

  20. Meta-analysis of survival prediction with Palliative Performance Scale.

    Science.gov (United States)

    Downing, Michael; Lau, Francis; Lesperance, Mary; Karlson, Nicholas; Shaw, Jack; Kuziemsky, Craig; Bernard, Steve; Hanson, Laura; Olajide, Lola; Head, Barbara; Ritchie, Christine; Harrold, Joan; Casarett, David

    2007-01-01

    This paper aims to reconcile the use of Palliative Performance Scale (PPSv2) for survival prediction in palliative care through an international collaborative study by five research groups. The study involves an individual patient data meta-analysis on 1,808 patients from four original datasets to reanalyze their survival patterns by age, gender, cancer status, and initial PPS score. Our findings reveal a strong association between PPS and survival across the four datasets. The Kaplan-Meier survival curves show each PPS level as distinct, with a strong ordering effect in which higher PPS levels are associated with increased length of survival. Using a stratified Cox proportional hazard model to adjust for study differences, we found females lived significantly longer than males, with a further decrease in hazard for females not diagnosed with cancer. Further work is needed to refine the reporting of survival times/probabilities and to improve prediction accuracy with the inclusion of other variables in the models.