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Sample records for survival tips mental

  1. Psychiatric Mental Health Leadership at the Tipping Point.

    Science.gov (United States)

    R Delaney, Kathleen

    2015-05-01

    Currently the United States health care system is responding to the Patient Protection and Affordable Care Act (PPACA) and the vision it contains for health care transformation. Along with sweeping changes in service delivery and payment structures, health care reform has championed concepts such as patient-centered care, integrated care, and wellness. Although these are not new ideas, their adaptation, in both ideology and service design has been accelerated in the context for reform. Indeed they are reaching a tipping point; the point where ideas gain wide acceptance and become influential trends. Although psychiatric mental health (PMH) nurses have been active in wellness, patient-centered care, and integrated care, at the current time they seem to be situated peripheral to these national trends. Increased presence of PMH nurses will facilitate their contribution to the development of these concepts within service structures and interventions. To increase knowledge and appreciation of PMH nurses' practice and unique perspective on these issues, leaders are needed who will connect and effectively communicate PMH nursing efforts to the broader health care arena. This article outlines the events that created a context for these three concepts (patient-centered care, wellness, and integrated care), and I suggest why they have reached a tipping point and discuss the need for greater PMH nursing presence in the American national dialog and the role of nursing leaders in facilitating these connections.

  2. Mental vulnerability and survival after cancer

    DEFF Research Database (Denmark)

    Nakaya, Naoki; Bidstrup, Pernille E; Eplov, Lene F

    2009-01-01

    BACKGROUND: It has been hypothesized that personality traits affect survival after cancer, but studies have produced inconsistent results. This study examined the association between mental vulnerability and survival after cancer in Denmark in a prospective cohort study. METHODS: Between 1976...... and 2001, 12733 residents of Copenhagen completed a questionnaire eliciting information on a 12-item mental vulnerability scale, as well as various personal data. Follow-up in the Danish Cancer Registry until 2003 identified 884 incident cases of primary cancer, and follow-up for death from the date...... of cancer diagnosis until 2003 identified 382 deaths. Mental vulnerability scores were divided into 4 approximately equal-sized groups. Cox proportional hazards regression models were used to estimate the hazard ratio (HR) of all-cause mortality. RESULTS: Multivariate HR for all-cause mortality for persons...

  3. Twelve tips on how to survive PBL as a medical student.

    Science.gov (United States)

    Bate, E; Taylor, D C M

    2013-01-01

    Starting medical school can be both exciting and daunting. This is particularly the case when the style of learning is different from that which has been experienced previously. For many students, their first experience of learning through a problem-based learning (PBL) approach is when they commence their medical student programme. This article provides 12 tips on how to survive PBL as a medical student. The tips have been based on the authors' experience of PBL and the current literature evidence base. A chronological order was used for the tips to guide the reader, whether student or PBL facilitator, through tips for the various stages of the PBL process. These 12 tips provide students and PBL facilitators with 12 practical tips to help them to realise the learning process and rationale for PBL. The tips commence with surviving the initial PBL sessions and continue through the process, finishing with the use of PBL in the clinical setting where the written scenarios are replaced by patient case histories. Using a PBL approach facilitates the learning of clinical and science knowledge in context through clinical scenarios, whilst working and learning together as a group. It is envisaged that these tips will be beneficial for PBL facilitators working with students that are new to PBL, and for the PBL students themselves.

  4. Mental Game Myths and Tips for Coaches and Athletes

    Science.gov (United States)

    Vealey, Robin S.

    2015-01-01

    What often seems intuitive and well-meaning as a mental game strategy may be ineffective or detrimental to athletes, based on the evolution of knowledge in sport psychology. This article describes three popular ideas about the mental game and identifies them as myths, based on experience and research. These myths are (1) mental training should…

  5. The survival of salmonellas on finger-tips and transfer of the organisms to foods.

    Science.gov (United States)

    Pether, J V; Gilbert, R J

    1971-12-01

    The survival of salmonellas on the finger-tips is considered with reference to the ease with which they can be transferred to food by handling.Escherichia coli and several Salmonella serotypes were shown to survive on the finger-tips for various periods of time, for example, S. anatum could be recovered 3 hr. after artificially contaminating them with between 500 and 2000 organisms. S. anatum could also be recovered from the finger-tips after contaminating them with more than 6000 organisms followed by a 15 sec. hand-wash 10 min. later. Similarly, the survivors from minimal inocula of less than 100 S. anatum/finger-tip were, after 10 min., still capable of infecting samples of corned beef and ham. E. coli was isolated from the finger-tips of 13 of 110 butchers soon after they had left the meat line at a meat products factory, but was not detected on the finger-tips of 100 volunteers at the Central Public Health Laboratory.The implications of the present findings to the spread of salmonellas from raw to cooked foods, and the relevance of this to outbreaks of Salmonella infection in the general population and in hospitals, are discussed.

  6. Circulating Elastin Fragments Are Not Affected by Hepatic, Renal and Hemodynamic Changes, But Reflect Survival in Cirrhosis with TIPS

    DEFF Research Database (Denmark)

    Nielsen, M. J.; Lehmann, J; Leeming, D J

    2015-01-01

    before TIPS with higher levels in the hepatic vein. Interestingly, the circulating ELM levels remained unchanged after TIPS. The circulating levels of ELM in portal and hepatic veins correlated with platelet counts and inversely with serum sodium. Hepatic venous levels of ELM were higher in CHILD C...... compared to CHILD A and B and were associated with the presence of ascites. Patients with high levels of ELM in the hepatic veins before TIPS showed poorer survival. In multivariate analysis ELM levels in the hepatic veins and MELD were independent predictors of mortality in these patients. CONCLUSION...

  7. Twelve tips for choosing and surviving a PhD in medical education - a student perspective.

    Science.gov (United States)

    Bryan, Billy; Church, Helen R

    2017-11-01

    The decision to undertake a PhD in medical education could mark a critical point in defining your future career. Attaining the highest level of degree in such a diverse and rewarding area as medical education may not only provide you with an opportunity to undertake important new research, but could also unlock different job opportunities. As is often the case, such rewards are not gained lightly. There can be real challenges in making the decision to undertake and then to successfully navigate a PhD. The specific subject and process of each doctorate is unique, leaving many prospective and current students uncertain as to what to expect. We offer our twelve tips from the perspective of two current PhD students to help guide those who share our interest in medical education and are considering doctoral study.

  8. Mental disorders and general well-being in cardiology outpatients--6-year survival

    DEFF Research Database (Denmark)

    Birket-Smith, Morten; Hansen, Baiba H; Hanash, Jamal A

    2009-01-01

    OBJECTIVE: Long-term survival in a sample of cardiology outpatients with and without mental disorders and other psychosocial risk factors. METHODS: In a cardiology outpatient setting, 103 consecutive patients were asked to participate in the study. Of these, 86 were included and screened for mental...... disorder with the Primary Care Evaluation of Mental Disorders; Structured Clinical Interview for DSM-III-R, Non-Patient Edition, psychosis screening; the Clock Drawing Test; and the WHO-5 Well-Being Index. The cardiologists were asked in each patient to rate the severity of somatic disease and mental...

  9. Teaching Community Survival Skills to Mentally Retarded Adults: A Review and Analysis.

    Science.gov (United States)

    Martin, James E.; And Others

    1982-01-01

    The article reviews research on training mentally retarded adults in the following community survival skills: travel training, money management, meal preparation, clothing and personal care, telephone skill, housekeeping, self-medication, leisure skills, social skills, and conversation. Results are said to indicate the value of behavioral…

  10. Combined thermotherapy and cryotherapy for efficient virus eradication: relation of virus distribution, subcellular changes, cell survival and viral RNA degradation in shoot tips.

    Science.gov (United States)

    Wang, Qiaochun; Cuellar, Wilmer J; Rajamäki, Minna-Liisa; Hirata, Yukimasa; Valkonen, Jari P T

    2008-03-01

    Accumulation of viruses in vegetatively propagated plants causes heavy yield losses. Therefore, supply of virus-free planting materials is pivotal to sustainable crop production. In previous studies, Raspberry bushy dwarf virus (RBDV) was difficult to eradicate from raspberry (Rubus idaeus) using the conventional means of meristem tip culture. As shown in the present study, it was probably because this pollen-transmitted virus efficiently invades leaf primordia and all meristematic tissues except the least differentiated cells of the apical dome. Subjecting plants to thermotherapy prior to meristem tip culture heavily reduced viral RNA2, RNA3 and the coat protein in the shoot tips, but no virus-free plants were obtained. Therefore, a novel method including thermotherapy followed by cryotherapy was developed for efficient virus eradication. Heat treatment caused subcellular alterations such as enlargement of vacuoles in the more developed, virus-infected cells, which were largely eliminated following subsequent cryotherapy. Using this protocol, 20-36% of the treated shoot tips survived, 30-40% regenerated and up to 35% of the regenerated plants were virus-free, as tested by ELISA and reverse transcription loop-mediated isothermal amplification. Novel cellular and molecular insights into RBDV-host interactions and the factors influencing virus eradication were obtained, including invasion of shoot tips and meristematic tissues by RBDV, enhanced viral RNA degradation and increased sensitivity to freezing caused by thermotherapy, and subcellular changes and subsequent death of cells caused by cryotherapy. This novel procedure should be helpful with many virus-host combinations in which virus eradication by conventional means has proven difficult.

  11. Tipping Point

    Medline Plus

    Full Text Available ... OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture ...

  12. Tipping Point

    Medline Plus

    Full Text Available ... and furniture, appliance and tv tip-overs. The force of a large television falling from tipping furniture ... 50 lb. TV falls with about the same force as child falling from the third story of ...

  13. Tipping Point

    Medline Plus

    Full Text Available ... death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ... tv tip-overs. The force of a large television falling from tipping furniture can be staggering. A ...

  14. Tipping Point

    Medline Plus

    Full Text Available ... en español Blog About OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by ... danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe ...

  15. Mental health selection and income support dynamics: multiple spell discrete-time survival analyses of welfare receipt.

    Science.gov (United States)

    Kiely, Kim M; Butterworth, Peter

    2014-04-01

    The higher occurrence of common psychiatric disorders among welfare recipients has been attributed to health selection, social causation and underlying vulnerability. The aims of this study were to test for the selection effects of mental health problems on entry and re-entry to working-age welfare payments in respect to single parenthood, unemployment and disability. Nationally representative longitudinal data were drawn from the Household Income and Labour Dynamics in Australia survey. Multiple spell discrete-time survival analyses were conducted using multinomial logistic regression models to test if pre-existing mental health problems predicted transitions to welfare. Analyses were stratified by sex and multivariate adjusted for mental health problems, father's occupation, socioeconomic position, marital status, employment history, smoking status and alcohol consumption, physical function and financial hardship. All covariates were modelled as either lagged effects or when a respondent was first observed to be at risk of income support. Mental health problems were associated with increased risk of entry and re-entry to disability, unemployment and single parenting payments for women, and disability and unemployment payments for men. These associations were attenuated but remained significant after adjusting for contemporaneous risk factors. Although we do not control for reciprocal causation, our findings are consistent with a health selection hypothesis and indicate that mental illness may be a contributing factor to later receipt of different types of welfare payments. We argue that mental health warrants consideration in the design and targeting of social and economic policies.

  16. Survival

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — These data provide information on the survival of California red-legged frogs in a unique ecosystem to better conserve this threatened species while restoring...

  17. CPAP Tips

    Medline Plus

    Full Text Available ... total__ Find out why Close CPAP Tips from FDA USFoodandDrugAdmin Loading... Unsubscribe from USFoodandDrugAdmin? Cancel Unsubscribe Working... ... tips from the U.S. Food and Drug Administration (FDA) on how to safely and effectively use your ...

  18. Technology Tips

    Science.gov (United States)

    Mathematics Teacher, 2004

    2004-01-01

    Some inexpensive or free ways that enable to capture and use images in work are mentioned. The first tip demonstrates the methods of using some of the built-in capabilities of the Macintosh and Windows-based PC operating systems, and the second tip describes methods to capture and create images using SnagIt.

  19. Tipping Point

    Medline Plus

    Full Text Available ... OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point ... 24 hours a day. For young children whose home is a playground, it’s the best way to ...

  20. Survival of the scheming: a genetically informed link between the dark triad and mental toughness.

    Science.gov (United States)

    Onley, Michael; Veselka, Livia; Schermer, Julie Aitken; Vernon, Philip A

    2013-12-01

    The present study is the first behavioral genetic investigation of the Dark Triad traits of personality, consisting of Machiavellianism, narcissism, and psychopathy, and the variable of mental toughness, reflecting individual differences in the ability to cope when under pressure. The purpose of this investigation was to explore a potential explanation for the success of individuals exhibiting the Dark Triad traits in workplace and social settings. Participants were adult twins who completed the MACH-IV, the Narcissistic Personality Inventory, and the Self-Report Psychopathy Scale assessing Machiavellianism, narcissism, and psychopathy, respectively, as well as the MT48, measuring mental toughness. Correlational analyses of the data revealed significant positive phenotypic associations between mental toughness and narcissism. Psychopathy and Machiavellianism, however, both showed some significant negative phenotypic correlations with mental toughness. Bivariate behavioral genetic analyses of the data were conducted to assess the extent to which these significant phenotypic correlations were attributable to common genetic and/or common environmental factors. Results indicate that correlations between narcissism and mental toughness were attributable primarily to common non-shared environmental factors, correlations between Machiavellianism and mental toughness were influenced by both common genetic and common non-shared environmental factors, and the correlations between psychopathy and mental toughness were attributable entirely to correlated genetic factors. Implications of these findings in the context of etiology and organizational adaptation are discussed.

  1. Struggling to survive: sexual assault, poverty, and mental health outcomes of African American women.

    Science.gov (United States)

    Bryant-Davis, Thema; Ullman, Sarah E; Tsong, Yuying; Tillman, Shaquita; Smith, Kimberly

    2010-01-01

    A substantial body of research documents the mental health consequences of sexual assault including, but not limited to, depression, posttraumatic stress disorder, substance use, and suicidality. Far less attention has been given to the mental health effects of sexual assault for ethnic minority women or women living in poverty. Given African American women's increased risk for sexual assault and increased risk for persistent poverty, the current study explores the relationship between income and mental health effects within a sample of 413 African American sexual assault survivors. Hierarchical regression analyses revealed that after controlling for childhood sexual abuse there were positive relationships between poverty and mental health outcomes of depression, posttraumatic stress disorder, and illicit drug use. There was no significant relationship between poverty and suicidal ideation. Counseling and research implications are discussed.

  2. Tipping Point

    Medline Plus

    Full Text Available ... fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash format. Almost ... accidents involving young children and furniture, appliance and tv tip-overs. The force of a large television ...

  3. Tipping Point

    Medline Plus

    Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... see news reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The ...

  4. Tipping Point

    Medline Plus

    Full Text Available ... of a large television falling from tipping furniture can be staggering. A 50 lb. TV falls with ... story of a building. That kind of impact can kill a child or cause severe injuries. About ...

  5. Tipping Point

    Medline Plus

    Full Text Available ... appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch ... reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The force of ...

  6. CPAP Tips

    Medline Plus

    Full Text Available ... sleeping? Here are some tips from the U.S. Food and Drug Administration (FDA) on how to safely and effectively use your CPAP device. Category Education License Standard YouTube License Show more Show less ...

  7. Tipping Point

    Medline Plus

    Full Text Available ... 16,000 (mostly young children) were treated in emergency rooms for tip-over related injuries in 2006, ... unaware of the deadly danger of this hidden hazard. Parents should include securing TVs, furniture, and appliances ...

  8. Tipping Point

    Medline Plus

    Full Text Available ... CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in ... to prevent a tip-over tragedy. Share Post Facebook Twitter Google Plus Reddit Connect with Me:  Visit ...

  9. Tipping Point

    Medline Plus

    Full Text Available ... 24 hours a day. For young children whose home is a playground, it’s the best way to prevent a tip-over tragedy. Share Post Facebook Twitter ... Security, and Legal Notice | Accessibility Policy | Open Government @ CPSC | ...

  10. CPAP Tips

    Medline Plus

    Full Text Available ... 3 Tips for Sleeping With a CPAP - Duration: 2:02. WebMD 42,375 views 2:02 About to spend my first night using ... 534 views 4:39 CPAP Mask Tutorial - Duration: 2:19. somnomedics 35,554 views 2:19 CPAP ...

  11. Tipping Point

    Medline Plus

    Full Text Available ... 24 hours a day. For young children whose home is a playground, it’s the best way to prevent a tip-over tragedy. Share Post Facebook Twitter Google Plus Reddit Connect with Me:  Visit other Web ...

  12. CPAP Tips

    Medline Plus

    Full Text Available ... sleeping? Here are some tips from the U.S. Food and Drug Administration (FDA) on how to safely ... Copyright Creators Advertise Developers +YouTube Terms Privacy Policy & Safety Send feedback Test new features Loading... Working... Sign ...

  13. CPAP Tips

    Medline Plus

    Full Text Available ... are some tips from the U.S. Food and Drug Administration (FDA) on how to safely and effectively ... views 3:03 FDA CDER Regulatory Science: Improving Drug Review with Data Standards - Duration: 3:01. USFoodandDrugAdmin ...

  14. CPAP Tips

    Medline Plus

    Full Text Available ... are some tips from the U.S. Food and Drug Administration (FDA) on how to safely and effectively ... views 9:28 FDA CDER Regulatory Science: Improving Drug Review with Data Standards - Duration: 3:01. USFoodandDrugAdmin ...

  15. CPAP Tips

    Medline Plus

    Full Text Available ... in to report inappropriate content. Sign in Transcript Statistics Add translations 200,671 views Like this video? ... 3 Tips for Sleeping With a CPAP - Duration: 2:02. WebMD 57,416 views 2:02 How ...

  16. CPAP Tips

    Medline Plus

    Full Text Available ... some tips from the U.S. Food and Drug Administration (FDA) on how to safely and effectively use ... WebMD 42,592 views 2:02 How CPAP works 5_23_11.wmv - Duration: 3:03. KenWarnerRemoteSleep ...

  17. CPAP Tips

    Medline Plus

    Full Text Available ... 3 Tips for Sleeping With a CPAP - Duration: 2:02. WebMD 44,809 views 2:02 Airing: the first hoseless, maskless, micro-CPAP ... 569 views 6:50 CPAP Mask Tutorial - Duration: 2:19. somnomedics 36,067 views 2:19 How ...

  18. Tip enhancement

    CERN Document Server

    Kawata, Satoshi

    2007-01-01

    This book discusses the recent advances in the area of near-field Raman scattering, mainly focusing on tip-enhanced and surface-enhanced Raman scattering. Some of the key features covered here are the optical structuring and manipulations, single molecule sensitivity, analysis of single-walled carbon nanotubes, and analytic applications in chemistry, biology and material sciences. This book also discusses the plasmonic materials for better enhancement, and optical antennas. Further, near-field microscopy based on second harmonic generation is also discussed. Chapters have been written by some of the leading scientists in this field, who present some of their recent work in this field.·Near-field Raman scattering·Tip-enhanced Raman spectroscopy·Surface-enhanced Raman spectroscopy·Nano-photonics·Nanoanalysis of Physical, chemical and biological materials beyond the diffraction limits·Single molecule detection

  19. Practical Tips to Hack your NGO

    OpenAIRE

    Pedro Marcun

    2012-01-01

    Pedro Marcun provides some useful tips to make NGOs work, from sharing data, to being accountable and to using all the possible tools on the internet. Only in this way, will NGOs survive in an interconnected world.

  20. Tip Refinement Grafts: The Designer Tip.

    Science.gov (United States)

    Daniel, Rollin K

    2009-01-01

    In cosmetic rhinoplasty, the patient's satisfaction is most often determined by the quality of the tip surgery, but perfecting a technique for consistently attractive tips can be challenging. As a result, rhinoplasty surgery is now entering a new era of "designer tip" operations, wherein surgeons can employ a combination of open suture tip techniques and tip refinement grafts to achieve consistent results. The grafts are made from excised lateral crural cartilage and, depending upon the specific aesthetic goals, the shape can include the following:domal, shield, diamond, folded, or combination. It is possible to alter dome-defining points, tip point, projection,definition, volume, and size and shape. A study of 100 consecutive female rhinoplasties indicated that tip sutures alone were used in 36% of cases, while a tip refinement graft was added to a sutured tip in 59% of cases.

  1. To tip or not to tip?

    OpenAIRE

    Saayman, Melville

    2014-01-01

    Tipping is an important source of income for a variety of occupations in the hospitality and tourism industry. One such occupation is waitressing and although much research has been done, especially in America, very little has been done in African countries. The purpose of this paper is therefore to determine the reasons why people tip or do not tip, as well as which socio-demographic and behavioural variables have the greatest influence on tipping. A survey was conducted at restaurants durin...

  2. Tips for Daily Living

    Science.gov (United States)

    ... over the country who’ve created or discovered adaptive and often innovative ways to get things done! Submit your tips today! Check out our Tips for Submitting Tips ! Take a video (it can even be on a smartphone!) or write down your tips. Complete the submission ...

  3. Supermodularity and Tipping

    OpenAIRE

    Geoffrey Heal; Howard Kunreuther

    2006-01-01

    We model tipping as a game-theoretic phenomenon and investigate the connection between supermodular games, tipping of equilibria and cascading, and apply the results to issues that arise in the context of homeland security and computer security. We show that tipping and cascading can occur in supermodular games and that "increasing differences"is a sufficient condition for tipping. Supermodularity and tipping of equilibria are closely related. We relate our results to Schelling%u2019s early w...

  4. Healthy Vision Tips

    Science.gov (United States)

    ... NEI for Kids > Healthy Vision Tips All About Vision About the Eye Ask a Scientist Video Series ... Links to More Information Optical Illusions Printables Healthy Vision Tips Healthy vision starts with you! Use these ...

  5. Four Tips for Surviving Standardized Testing

    Science.gov (United States)

    Martin, Anna

    2012-01-01

    As the tenth anniversary of NCLB has come and gone, both new and experienced educators continue to wrestle yearly with the standardized testing culture that has pervaded the educational experience of nearly every American child and teacher. Despite the requests for waivers to exempt certain states from NCLB, the majority of students and their…

  6. Research Battles: Survival Tips From a Veteran

    Science.gov (United States)

    Isaacs, Linda L.

    2015-01-01

    Studies of nonorthodox medical treatments may go awry because of inherent flaws in designs that are better suited for trials of pharmaceutical products. Unintended consequences may follow from efforts at randomization, the lack of lead-in periods, required visits for medical assessment, inadequate screening, and a lack of trial publicity. A veteran of a mismanaged trial shares her experiences. PMID:26770164

  7. The TIPS Liquidity Premium

    DEFF Research Database (Denmark)

    Andreasen, Martin Møller; Christensen, Jens H.E.; Simon Riddell, Simon

    We introduce an arbitrage-free term structure model of nominal and real yields that accounts for liquidity risk in Treasury inflation-protected securities (TIPS). The novel feature of our model is to identify liquidity risk from individual TIPS prices by accounting for the tendency that TIPS, lik...

  8. Tip studies using CFD and comparison with tip loss models

    DEFF Research Database (Denmark)

    Hansen, Martin Otto Laver; Johansen, J.

    2004-01-01

    The flow past a rotating LM8.2 blade equipped with two different tips are computed using CFD. The different tip flows are analysed and a comparison with two different tip loss models is made. Keywords: tip flow, aerodynamics, CFD......The flow past a rotating LM8.2 blade equipped with two different tips are computed using CFD. The different tip flows are analysed and a comparison with two different tip loss models is made. Keywords: tip flow, aerodynamics, CFD...

  9. Arctic climate tipping points.

    Science.gov (United States)

    Lenton, Timothy M

    2012-02-01

    There is widespread concern that anthropogenic global warming will trigger Arctic climate tipping points. The Arctic has a long history of natural, abrupt climate changes, which together with current observations and model projections, can help us to identify which parts of the Arctic climate system might pass future tipping points. Here the climate tipping points are defined, noting that not all of them involve bifurcations leading to irreversible change. Past abrupt climate changes in the Arctic are briefly reviewed. Then, the current behaviour of a range of Arctic systems is summarised. Looking ahead, a range of potential tipping phenomena are described. This leads to a revised and expanded list of potential Arctic climate tipping elements, whose likelihood is assessed, in terms of how much warming will be required to tip them. Finally, the available responses are considered, especially the prospects for avoiding Arctic climate tipping points.

  10. Tip Studies using CFD and Comparison with Tip Loss Models

    DEFF Research Database (Denmark)

    Hansen, Martin Otto Laver

    2004-01-01

    The flow past a 95 kW Tellus rotor equipped with LM8.2 blades is computed using computational fluid dynamics for a standard tip and a swept tip. The difference in the near-tip flow for the two tips for various tip speed ratios is examined and 3D airfoil data are extracted. The radial distribution...

  11. Sleep Tips for Children's Mental Health

    Science.gov (United States)

    ... the news, conflict-filled talk shows, and high-anxiety dramas. (Ideally, don't expose younger children to such material at all. Older children and ... sleep. Sleepiness and a sense of calm and relaxation are side effects of acupuncture. ... strenuous exercise within 2 hours of bedtime. Avoid stimulating TV, ...

  12. Tip-modified Propellers

    DEFF Research Database (Denmark)

    Andersen, Poul

    1999-01-01

    wings. The literature on four different designs is reviewed: the end-plate propeller; the two-sided, shifted end-plate propeller; the tip-fin propeller; and the bladelet propeller. The conclusion is that it is indeed possible to design tip-modified propellers that, relative to an optimum conventional...

  13. 10 Data Visualization Tips

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    1. 10 Data Visualization Tips. Data visualizations are an effective tool to communicate research. But to realize their potential, designers should follow these tips to help readers decode their visualizations. 1. Keep it simple! This is the golden rule. Always choose the simplest way to convey your information. 2. Have a specific ...

  14. Southwestern Pine Tip Moth

    Science.gov (United States)

    Daniel T. Jennings; Robert E. Stevens

    1982-01-01

    The southwestern pine tip moth, Rhyacionia neomexicana (Dyar), injures young ponderosa pines (Pinus ponderosa Dougl. ex Laws) in the Southwest, central Rockies, and midwestern plains. Larvae feed on and destroy new, expanding shoots, often seriously reducing terminal growth of both naturally regenerated and planted pines. The tip moth is especially damaging to trees on...

  15. ADHD: Tips to Try

    Science.gov (United States)

    ... Situations Talking to Your Parents - or Other Adults ADHD: Tips to Try KidsHealth > For Teens > ADHD: Tips to Try Print A A A en español TDAH: Consejos que puedes probar ADHD , short for attention deficit hyperactivity disorder , is a ...

  16. Survived but feeling vulnerable and insecure: a qualitative study of the mental preparation for RTW after breast cancer treatment

    Science.gov (United States)

    2012-01-01

    Background Improvements in treatment have resulted in an increasing number of cancer survivors potentially being able to return to work after medical treatment. In this paper we focus on the considerations regarding return to work (RTW) of breast cancer absentees in the Belgian context and how these considerations are related to reactions from their social environment. Methods A qualitative study was performed to understand the RTW considerations of Belgian breast cancer absentees who had undergone breast cancer surgery in 2006. Twenty-two participants (mean age 46) were included and interviewed between May 2008 and August 2009 in their personal environment. An in-depth analysis (Grounded Theory) took place using the Qualitative Analysis Guide of Leuven (Quagol). Results Before the actual RTW, breast cancer employees try to build an image of the future resumption of work based on medical grounds and their knowledge of the workplace. Four matters are considered prior to RTW: (i) women want to leave the sick role and wish to keep their job; (ii) they consider whether working is worth the effort; (iii) they reflect on their capability; and (iv) they have doubts about being accepted in the workplace after returning. These inner thoughts are both product and input for the interaction with the social environment. The whole process is coloured by uncertainty and vulnerability. Conclusion Our study demonstrated that mental preparation for RTW is not a linear process of improvement. It shows a detailed picture of four types of considerations made by breast cancer survivors before they actually resume work. Vulnerability appears to be an overarching theme during mental preparation. As the social environment plays an important role, people from that environment must become more aware of their influence on decreasing or increasing a woman’s vulnerability while preparing for RTW. PMID:22824548

  17. Survived but feeling vulnerable and insecure: a qualitative study of the mental preparation for RTW after breast cancer treatment

    Directory of Open Access Journals (Sweden)

    Tiedtke Corine

    2012-07-01

    Full Text Available Abstract Background Improvements in treatment have resulted in an increasing number of cancer survivors potentially being able to return to work after medical treatment. In this paper we focus on the considerations regarding return to work (RTW of breast cancer absentees in the Belgian context and how these considerations are related to reactions from their social environment. Methods A qualitative study was performed to understand the RTW considerations of Belgian breast cancer absentees who had undergone breast cancer surgery in 2006. Twenty-two participants (mean age 46 were included and interviewed between May 2008 and August 2009 in their personal environment. An in-depth analysis (Grounded Theory took place using the Qualitative Analysis Guide of Leuven (Quagol. Results Before the actual RTW, breast cancer employees try to build an image of the future resumption of work based on medical grounds and their knowledge of the workplace. Four matters are considered prior to RTW: (i women want to leave the sick role and wish to keep their job; (ii they consider whether working is worth the effort; (iii they reflect on their capability; and (iv they have doubts about being accepted in the workplace after returning. These inner thoughts are both product and input for the interaction with the social environment. The whole process is coloured by uncertainty and vulnerability. Conclusion Our study demonstrated that mental preparation for RTW is not a linear process of improvement. It shows a detailed picture of four types of considerations made by breast cancer survivors before they actually resume work. Vulnerability appears to be an overarching theme during mental preparation. As the social environment plays an important role, people from that environment must become more aware of their influence on decreasing or increasing a woman’s vulnerability while preparing for RTW.

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... the liver). Portal hypertension can also occur in children, although children are much less likely to require a TIPS. ... intentionally to solve the problem. Although extremely rare, children may also require a TIPS procedure. TIPS in ...

  19. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... intentionally to solve the problem. Although extremely rare, children may also require a TIPS procedure. TIPS in ...

  20. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... risks? What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A transjugular intrahepatic ... top of page What are some common uses of the procedure? A TIPS is used to treat ...

  1. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A transjugular intrahepatic ... of page What are some common uses of the procedure? A TIPS is used to treat the ...

  2. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... vs. risks? What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A ... likely to require a TIPS. top of page What are some common uses of the procedure? A ...

  3. Eye Drop Tips

    Science.gov (United States)

    ... Involved News About Us Donate In This Section Eye Drop Tips en Español email Send this article ... the reach of children. Steps For Putting In Eye Drops: Start by tilting your head backward while ...

  4. Incontinence Treatment: Dietary Tips

    Science.gov (United States)

    ... well as some fruits). Some foods are gas producing (e.g., beans, cabbage, legumes, cauliflower, broccoli, lentils, ... supporting IFFGD with a small tax-deductible donation. Lifestyle Changes Dietary Tips Medication Bowel Management Biofeedback Surgical ...

  5. Tips from the Classroom.

    Science.gov (United States)

    Hess, Natalie; And Others

    1995-01-01

    Six classroom tips for language teachers focus on creating a congenial classroom environment, integrating listening and reading skills, teaching idioms from tabloid newspapers, cooperative learning in honors courses, grammar games, and teaching culture through personalized automobile license plate messages. (MDM)

  6. Tips for Chronic Pain

    Science.gov (United States)

    Patient Education Sheet Tips for Chronic Pain The SSF thanks Stuart S. Kassan, MD, FACP, Clinical Professor of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, for authoring ...

  7. Childhood IQ and survival to 79: Follow-up of 94% of the Scottish Mental Survey 1947.

    Science.gov (United States)

    Čukić, Iva; Brett, Caroline E; Calvin, Catherine M; Batty, G David; Deary, Ian J

    2017-07-01

    To extend previous literature that suggests higher IQ in youth is associated with living longer. Previous studies have been unable to assess reliably whether the effect differs across sexes and ages of death, and whether the effect is graded across different levels of IQ. We test IQ-survival associations in 94% of the near-entire population born in Scotland in 1936 who took an IQ test at age 11 (n = 70,805) and were traced in a 68-year follow-up. Higher IQ at age 11 years was associated with a lower risk of death (HR = 0.80, 95% CI = 0.79, 0.81). The decline in risk across categories of IQ scores was graded across the full range with the effect slightly stronger in women (HR = 0.79, 95% CI = 0.77, 0.80) than in men (HR = 0.82, 95% CI = 0.81, 0.84). Higher IQ had a significantly stronger association with death before and including age 65 (HR = 0.76, 95% CI = 0.74, 0.77) than in those participants who died at an older age (HR = 0.79, 95% CI = 0.78, 0.80). Higher childhood IQ is associated with lower risk of all-cause mortality in both men and women. This is the only near-entire population study to date that examines the association between childhood IQ and mortality across most of the human life course.

  8. An effective disinfection protocol for plant regeneration from shoot tip ...

    African Journals Online (AJOL)

    An effective method of disinfection protocol and micropropagation with an enhanced survival rate of explants and reduced phenol induced browning in strawberry was developed. The survival rate of three genotypes was between 89.2 - 100%. Shoot tip were able to develop into plantlet on a hormone-free MS medium when ...

  9. Taxicab tipping and sunlight.

    Science.gov (United States)

    Devaraj, Srikant; Patel, Pankaj C

    2017-01-01

    Does the level of sunlight affect the tipping percentage in taxicab rides in New York City? We examined this question using data on 13.82 million cab rides from January to October in 2009 in New York City combined with data on hourly levels of solar radiation. We found a small but statistically significant positive relationship between sunlight and tipping, with an estimated tipping increase of 0.5 to 0.7 percentage points when transitioning from a dark sky to full sunshine. The findings are robust to two-way clustering of standard errors based on hour-of-the-day and day-of-the-year and controlling for day-of-the-year, month-of-the-year, cab driver fixed effects, weather conditions, and ride characteristics. The NYC cab ride context is suitable for testing the association between sunlight and tipping due to the largely random assignment of riders to drivers, direct exposure to sunlight, and low confounding from variation in service experiences.

  10. Tips for Energy Savers.

    Science.gov (United States)

    Department of Energy, Washington, DC.

    According to 1986 U.S. Department of Energy data, 48% of our residential energy is used to heat and cool our homes, 16% goes for heating water, 12% is used to refrigerators and freezers, and the remaining 24% goes into lighting, cooking, and running appliances. This booklet contains tips for saving energy, including sections on: (1) draft-proof…

  11. Tipping: Is it ever OK to skip the tip?

    National Research Council Canada - National Science Library

    N'dea Yancey-Bragg

    2017-01-01

    ..., the minimum wage for tipped workers can be also low as $2. 13. Delivery Apps like UberEats and Postmates don't require tips, although some offer suggested gratuities on their checkout page. (Uber on Tuesday just added the option to tip. ) Grubhub founder and CEO Matt Maloney strongly encourages a 10-15% tip. After all, delivery drivers aren't salaried work...

  12. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A transjugular intrahepatic ... code: Phone no: Thank you! Do you have a personal story about radiology? Share your patient story ...

  13. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... TIPS. top of page What are some common uses of the procedure? A TIPS is used to ... the scanner by a cord. Some exams may use different transducers (with different capabilities) during a single ...

  14. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... or bypass, without the risks that accompany open surgery. TIPS is a minimally invasive procedure that typically has a shorter recovery time than surgery. Your TIPS should have less of an effect ...

  15. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A transjugular intrahepatic ... taking our brief survey: Survey Do you have a personal story about radiology? Share your patient story ...

  16. The Tipping Points of Technology Development

    Directory of Open Access Journals (Sweden)

    Tauno Kekäle

    2014-07-01

    Full Text Available The tipping point, the decisive point in time in the competition between old and new, is an interesting phenomenon in physics of today. This aspect in technology acceptance is connected to many business decisions such as technology investments, product releases, resource allocation, sales forecasts and, ultimately, affects the profitability and even survival of a company. The tipping point itself is based on many stochastic and dynamic variables, and the process may at least partly be described as path-dependent. This paper analyses the tipping point from three aspects: (1 product performance, (2 features of the market and infrastructure (including related technologies and human network externalities, and (3 actions of the incumbents (including customer lock-in, systems lock-in, and sustaining innovation. The paper is based on the Bass s-curve idea and the technology trajectory concept proposed by Dosi. Three illustrative cases are presented to make the point of the multiple factors affecting technology acceptance and, thus, the tipping point. The paper also suggests outlines for further research in field of computer simulation.

  17. Economic Behavior of Restaurant Tipping

    OpenAIRE

    Tin-Chun Lin

    2007-01-01

    This paper offers a thoughtful discussion of social norms and alternative economic viewpoints and analysis of restaurant tipping behavior. A survey of Louisiana residents was conducted to collect public opinions about tipping. The analysis suggests that social norms are indeed the primary reason for diner tipping. As long as consumer behavior is guided by social norms, social norms will costs for diners. The conclusion suggests that if customer's tipping behavior were completely guided by soc...

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... liver disease are at greater risk for worsening liver failure after TIPS. If your liver failure is severe, a TIPS may not be the best use and a different procedure may be needed to control your symptoms. ... ordinarily filtered out by the liver. The TIPS may cause too much of these ...

  19. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... of page What are the limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening liver failure after TIPS. If your liver failure is severe, a TIPS may not be the best use and a different procedure may be needed ...

  20. Addressing Viral Hepatitis in People with Substance Use Disorders. Treatment Improvement Protocol (TIP) Series 53

    Science.gov (United States)

    Substance Abuse and Mental Health Services Administration, 2011

    2011-01-01

    Treatment Improvement Protocols (TIPs) are developed by the Center for Substance Abuse Treatment (CSAT), part of the Substance Abuse and Mental Health Services Administration (SAMHSA) within the U.S. Department of Health and Human Services (HHS). Each TIP involves the development of topic-specific best-practice guidelines for the prevention and…

  1. Tipping point leadership.

    Science.gov (United States)

    Kim, W Chan; Mauborgne, Renée

    2003-04-01

    When William Bratton was appointed police commissioner of New York City in 1994, turf wars over jurisdiction and funding were rife and crime was out of control. Yet in less than two years, and without an increase in his budget, Bratton turned New York into the safest large city in the nation. And the NYPD was only the latest of five law-enforcement agencies Bratton had turned around. In each case, he succeeded in record time despite limited resources, a demotivated staff, opposition from powerful vested interests, and an organization wedded to the status quo. Bratton's turnarounds demonstrate what the authors call tipping point leadership. The theory of tipping points hinges on the insight that in any organization, fundamental changes can occur quickly when the beliefs and energies of a critical mass of people create an epidemic movement toward an idea. Bratton begins by overcoming the cognitive hurdles that block organizations from recognizing the need for change. He does this by putting managers face-to-face with operational problems. Next, he manages around limitations on funds, staff, or equipment by concentrating resources on the areas that are most in need of change and that have the biggest payoffs. He meanwhile solves the motivation problem by singling out key influencers--people with disproportionate power due to their connections or persuasive abilities. Finally, he closes off resistance from powerful opponents. Not every CEO has the personality to be a Bill Bratton, but his successes are due to much more than his personality. He relies on a remarkably consistent method that any manager looking to turn around an organization can use to overcome the forces of inertia and reach the tipping point.

  2. AERODYNAMICS OF WING TIP SAILS

    Directory of Open Access Journals (Sweden)

    MUSHTAK AL-ATABI

    2006-06-01

    Full Text Available Observers have always been fascinated by soaring birds. An interesting feature of these birds is the existence of few feathers extending from the tip of the wing. In this paper, small lifting surfaces were fitted to the tip of a NACA0012 wing in a fashion similar to that of wing tip feathers. Experimental measurements of induced drag, longitudinal static stability and trailing vortex structure were obtained.The tests showed that adding wing tip surfaces (sails decreased the induced drag factor and increased the longitudinal static stability. Results identified two discrete appositely rotated tip vortices and showed the ability of wing tip surfaces to break them down and to diffuse them.

  3. Tipping: The Economics of a Social Norm

    OpenAIRE

    Ofer H. Azar

    2003-01-01

    Tipping illustrates the importance of social norms in motivating economic behavior. People tip because this is the social norm and disobeying norms results in social disapproval that creates emotional disutility. Tipping is also economically important: in the United States alone, millions of workers derive most of their income from tips, and annual tips amount to dozens of billions of dollars. I claim that tipping is not a single phenomenon; the economics of some tipping occasions is very dif...

  4. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... Images/Videos About Us News Physician Resources Professions Site Index A-Z Transjugular Intrahepatic Portosystemic Shunt (TIPS) Transjugular Intrahepatic Portosystemic Shunt or TIPS is a procedure that uses imaging guidance to connect the portal vein to the hepatic vein in the liver. ...

  5. TUBULARIZED INCISED PLATE (TIP) URETHROPLASTY:

    African Journals Online (AJOL)

    Objective: Recently, tubularized incised plate. (TIP) urethroplasty (Snodgrass repair) has gained popularity for the primary repair of distal and proximal hypospadias. This study was carried out to evaluate TIP urethro- plasty in the repair of failed and compli- cated hypospadias cases. Patients and Methods: This study was ...

  6. No-Fad Diet Tips

    Science.gov (United States)

    ... Works Healthy Workplace Food and Beverage Toolkit No-Fad Diet Tips Updated:Oct 18,2016 Tips - Think Smart: ... adapted with permission from American Heart Association No-Fad Diet: A Personal Plan for Healthy Weight Loss , Copyright © ...

  7. Choking and Strangulation Prevention Tips

    Science.gov (United States)

    ... Blog Videos Newsletter facebook twitter instagram pinterest gplus youtube Search Menu Why It Matters Who We Are What We Do Find Your Safe Kids Safe Kids Day Main menu Keeping All Kids Safe Safety Tips Get Involved 4 Star Charity Donate Safety Tips Age Group Babies 0–12 Months Little Kids 1– ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... liver disease are at greater risk for worsening liver failure after TIPS. If your liver failure is severe, a TIPS may not be the ... children are more likely to be performed before liver transplant in those with ascites or variceal ... 08, 2017 Send us your feedback Did you find the ...

  9. Torsional Phacoemulsification and Tip Selection

    Directory of Open Access Journals (Sweden)

    Fırat Helvacıoğlu

    2014-10-01

    Full Text Available One of the recent advances in cataract surgery is torsional phacoemulsification. It was developed to increase the efficacy of ultrasonic emulsification. In torsional phacoemulsification, the torsional movement of the tip is translated to side-to-side cutting action with the aid of bent phaco tips. Lens material is cut in both directions, rather than only during a forward stroke. The efficiency of this technique is further enhanced by an improvement in followability provided by the inherent non-repulsive nature of the side-to-side motion. Tip selection is very important for the efficiency of torsional phacoemulsification. Theoretically, there are 2 ways to enhance the cutting efficiency of the tip. First is the stroke length; the 22-degree bent 30-degree Kelman mini-flared tip cuts longer than the 12-degree bent 30-degree mini-flared Kelman tip. Second is the angulation or bevel; the higher the degree (45 degrees, the better cutting efficiency. Retrospective analyses of the previously published clinical studies clearly demonstrated that the efficacy of the torsional phacoemulsification has positive correlation with both the aperture angles and neck angles of the tips. (Turk J Ophthalmol 2014; 44: 392-5

  10. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... the TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This ... here Images × Image Gallery Radiologist and patient consultation. View full size with caption Pediatric Content Some imaging ...

  11. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... who typically need a TIPS have portal hypertension , meaning they have increased pressure in the portal vein ... community, you can search the ACR-accredited facilities database . This website does not provide cost information. The ...

  12. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... that would ordinarily pass through the liver to bypass the liver entirely, reducing high blood pressure in ... same physiological results as a surgical shunt or bypass, without the risks that accompany open surgery. TIPS ...

  13. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... blood draining from the bowel back to the heart while avoiding the liver. TIPS may successfully reduce ... blood away from the liver back to the heart). A stent is then placed in this tunnel ...

  14. Dining Out Tips by Cuisine

    Science.gov (United States)

    ... Preschoolers Infographic How to Make a Healthy Home Dietary Recommendations for Healthy Children Top 10 Tips to Help Children Develop Healthy Habits Fruit and Veggie Toolkit for Kids Healthy Foods ...

  15. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... surgery. Your TIPS should have less of an effect than open surgical bypass on future liver transplantation ... Encephalopathy can be treated with certain medications, a special diet or, by revising the stent, but sometimes ...

  16. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... complications, reported in fewer than five percent of cases, may include: occlusion, or complete blockage, of the ...

  17. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... the limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening liver failure ... patient who already has encephalopathy because of their liver disease may not be a good candidate for the ...

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... local anesthetic medications, general anesthesia or to contrast materials containing iodine (sometimes referred to as "dye" or " ... the placement of the TIPS stent, a contrast material will be injected in the hepatic vein to ...

  19. Tips for Relieving Dry Skin

    Science.gov (United States)

    ... skin include lactic acid, urea, hyaluronic acid, dimethicone, glycerin, lanolin, mineral oil, and petrolatum. Tip: Carry a ... using: Deodorant soaps Skin care products that contain alcohol, fragrance, retinoids, or alpha-hydroxy acid (AHA) Avoiding ...

  20. Tips to Prevent Tick Bites

    Science.gov (United States)

    Using the right insect repellent and other preventive actions can discourage ticks, mosquitoes, and other biting insects from landing on you. Tips include avoiding tick habitats and minimizing exposed skin.

  1. Tips to Prevent Mosquito Bites

    Science.gov (United States)

    Using the right insect repellent and other preventive actions can discourage mosquitoes from landing on you. Tips include removing mosquito habitats such as standing water, minimizing exposed skin, and staying indoors while mosquitoes are most active.

  2. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... Patients who typically need a TIPS have portal hypertension , meaning they have increased pressure in the portal ... leading to cirrhosis (scarring of the liver). Portal hypertension can also occur in children, although children are ...

  3. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... physician will numb an area just above your right collarbone with a local anesthetic . A very small ...

  4. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... anti-inflammatory drugs (NSAIDs) or blood thinners several days prior to your procedure and instructed to not ... overnight at the hospital for one or more days. What is Transjugular Intrahepatic Portosystemic Shunt (TIPS)? What ...

  5. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... liver back to the heart. top of page How should I prepare? You should report to your ... heart beat and blood pressure. top of page How does the procedure work? A TIPS reroutes blood ...

  6. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... the liver to the heart). A stent placed inside this pathway keeps it open and allows some ... keeps the shunt open (TIPS) is contained entirely inside the diseased liver, and is removed with it ...

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... portal vein to the hepatic vein in the liver. A small metal device called a stent is ... bowel back to the heart while avoiding the liver. TIPS may successfully reduce internal bleeding in the ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... the skin is a rare complication (it may happen in complex and lengthy procedures requiring ... risk for worsening liver failure after TIPS. If your liver failure is severe, a ...

  9. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... TIPS may successfully reduce internal bleeding in the stomach and esophagus in patients with cirrhosis. Tell your ... the liver into the veins of the spleen, stomach, lower esophagus, and intestines, causing enlarged vessels, bleeding ...

  10. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... in creating the TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient ... Send us your feedback Did you find the information you were looking for? Yes No Please type ...

  11. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... in an hour or two but may take up to several hours depending on the complexity of ... normal activities in seven to 10 days. Follow-up ultrasounds will be performed frequently after the TIPS ...

  12. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... treatments. The greatest difference in performing TIPS in children is their tremendous variability in size, physiology, and medical diseases. This can result in significant challenges in creating ...

  13. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... through the TIPS. Pressure will be applied to prevent any bleeding and the opening in the skin ... are monitored in intensive care beforehand and during recovery. You should be able to resume your normal ...

  14. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... to the heart while avoiding the liver. TIPS may successfully reduce internal bleeding in the stomach and ... conditions, allergies and medications you’re taking. You may be advised to stop taking aspirin, nonsteroidal anti- ...

  15. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... while avoiding the liver. TIPS may successfully reduce internal bleeding in the stomach and esophagus in patients ... site. Using ultrasound, the doctor will identify your internal jugular vein , which is situated above your collarbone, ...

  16. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... necessary, precautions will be taken to minimize radiation exposure to the baby. See the Safety page for ... surgery. Your TIPS should have less of an effect than open surgical bypass on future liver transplantation ...

  17. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... blood pressure and pulse during the procedure. A nurse or technologist will insert an intravenous (IV) line ...

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... you are pregnant and discuss any recent illnesses, medical conditions, allergies and medications you’re taking. You ... with ascites or variceal bleeding resistant to traditional medical treatments. The greatest difference in performing TIPS in ...

  19. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... top of page What are the benefits vs. risks? Benefits A TIPS is designed to produce the ... skin that does not have to be stitched. Risks Any procedure where the skin is penetrated carries ...

  20. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... seen in adults, often as a result of chronic liver problems leading to cirrhosis (scarring of the ... limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening liver failure ...

  1. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... system. This pressure buildup can cause blood to flow backward from the liver into the veins of ... does the procedure work? A TIPS reroutes blood flow in the liver and reduces abnormally high blood ...

  2. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... the hepatic vein in the liver. A small metal device called a stent is placed to keep ... open by the placement of a small, tubular metal device commonly called a stent . During a TIPS ...

  3. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... story about radiology? Share your patient story here Images × Image Gallery Radiologist and patient consultation. View full size ... X-Ray and CT Exams Contrast Materials Venography Images related to Transjugular Intrahepatic Portosystemic Shunt (TIPS) Sponsored ...

  4. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... X-Ray and CT Exams Contrast Materials Venography Images related to Transjugular Intrahepatic Portosystemic Shunt (TIPS) Sponsored by Please note RadiologyInfo.org is not a medical facility. Please contact your physician with specific medical ...

  5. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... procedure? A TIPS is used to treat the complications of portal hypertension, including: variceal bleeding , bleeding from ... is taken to mitigate these risks. Other possible complications of the procedure include: fever muscle stiffness in ...

  6. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... gained from the hepatic vein into the portal system using a TIPS needle (a special long needle ... may vary by geographic region. Discuss the fees associated with your prescribed ...

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... wear during the procedure. top of page What does the equipment look like? In this procedure, x- ... beat and blood pressure. top of page How does the procedure work? A TIPS reroutes blood flow ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... bear denotes child-specific content. Related Articles and Media Radiation Dose in X-Ray and CT Exams Contrast Materials Venography Images related to Transjugular Intrahepatic Portosystemic Shunt (TIPS) Sponsored ...

  9. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... look like? In this procedure, x-ray or ultrasound equipment, a stent, and a balloon-tipped catheter ... over a table on which the patient lies. Ultrasound scanners consist of a console containing a computer ...

  10. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... functions properly. top of page Who interprets the results and how do I get them? Prior to ... TIPS is designed to produce the same physiological results as a surgical shunt or bypass, without the ...

  11. Search Tips: MedlinePlus

    Science.gov (United States)

    ... of this page: https://medlineplus.gov/searchtips.html Search Tips To use the sharing features on this page, please enable JavaScript. How do I search MedlinePlus? The search box appears at the top ...

  12. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This page ... American College of Radiology (ACR) and the Radiological Society of North America (RSNA), comprising physicians with expertise ...

  13. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... liver. The shunt is kept open by the placement of a small, tubular metal device commonly called ... of the condition. To help plan for the placement of the TIPS stent, a contrast material will ...

  14. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... threatening and those patients are monitored in intensive care beforehand and during recovery. You should be able ... with ascites or variceal bleeding resistant to traditional medical treatments. The greatest difference in performing TIPS in ...

  15. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... of page What are some common uses of the procedure? A TIPS is used to treat the ... during the procedure. top of page What does the equipment look like? In this procedure, x-ray ...

  16. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... waves), as well as the type of body structure and composition of body tissue through which the ... the placement of the TIPS stent, a contrast material will be injected in the hepatic vein to ...

  17. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... who typically need a TIPS have portal hypertension , meaning they have increased pressure in the portal vein ... of bleeding that can occur can sometimes be life threatening and those patients are monitored in intensive ...

  18. Cycles Tipping the Scale between Death and Survival (=``Life")

    Science.gov (United States)

    Halberg, F.; Cornélissen, G.; Sothern, R. B.; Katinas, G. S.; Schwartzkopff, O.; Otsuka, K.

    Systematic chronobiologically interpreted ambulatory bloodpressure (BP) and heart rate (HR) monitoring (C-ABPM 7D/24H is now automatically possible; if continued around the clock over a week, this approach detects vascular variability disorders (VVDs) that include, among others, high BP itself and CHAT, short for circadian hyper-amplitude-tension. BP is never a constant ``true" (resting) value and can be more reliably diagnosed by CABPM 7d/24h as MESOR-hypertension, MH. CHAT carries a risk of hard events greater than MH and can be treated, among other VVDs, which if they coexist constitute vascular variability syndromes (VVSs). A project on The BIOsphere and the COSmos, BIOCOS (corne001@umn.edu), provides, in exchange for the data, cost-free analyses and the opportunity of obtaining monitors at a cost reduction of 80% complements the records from purely physical tools for surveilling the variable sun, by validating in the biosphere the reality of intermittent, aeolian envi ronmental spectral components that can be more consistent than their physical counterparts once they are coded in genes. C-ABPM 7D/24H indicates relevant associations of space weather with human health and ecology. Monitoring reveals, around and in living matter, a system of transdisciplinary cycles with common average periods, quantified with point-and-interval estimates of parameters. The cycles in space climate are critical in discussing global warming. The cycles' periods are described as congruent when their CIs (95\\ intervals) overlie or overlap and the amplitudes' CIs' lower limits are positive. Some congruent cycles in organisms, counterparts of the environmental day and the seasons, relate to electromagnetic radiation in the visible domain; these are the usually environmentally synchronized socio-photo-thermoperiodisms (photics). The biosphere also resonates with or is pulled or driven by nonstationary, environmental nonphotic cycles (nonphotics) -- particle emissi ons from the sun and the wider cosmos, cosmoheliogeomagnetics, ultraviolet flux, gravitation, acoustics and others. Nonphotics, a set of in part transdisciplinarily-novel spectral components, can be intermittent; when present, they coexist and compete with signatures of photic cycles, monitored, e.g., in BP and HR. Nonphotics of, e.g., about (˜) 1 week (circaseptans) and ˜17 months (transyears), characterize mood and performance, modulate and sometimes override society's (photic) schedules, even in dying suddenly either unintentionally or by one's own will or at the hand of others. Nonphotics persist, but are damped in physiology or in terrorism, when their environmental counterpart is not detected. Their elucidation provides information on how a set of cycles covering 18 orders of magnitude in the frequency domain of the biosphere bears on the question ``What is life?": a resonance of the biosphere with periods of its environment constitutes life itself.

  19. Lessons Learned Along the Way: Survival Tips for School Leaders.

    Science.gov (United States)

    Kelly, Dennis

    This book recounts the informal history of one educator's 20 years in administration. The stories describe common sense, nonsense, inspiration, and failures--reinforcing the idea that leaders should rely on experience, not books or lectures, to refine their leadership skills. The text tells stories about team work, admitting mistakes, listening to…

  20. You're it! How to psychologically survive an internal investigation, disciplinary proceeding, or legal action in the police, fire, medical, mental health, legal, or emergency services professions.

    Science.gov (United States)

    Miller, Laurence

    2009-01-01

    Rightly or wrongly, law enforcement, public safety, medical, mental health, legal, and emergency services professionals may have to face internal investigation, disciplinary measures, license suspension, criminal prosecution, civil lawsuits, and/or personal life disruption related to actions taken in the course of their work. This article describes the main categories of misconduct--or simply mistakes--that can cause different types of professionals to be investigated, charged, prosecuted, and/or sued. It next discusses the kinds of psychological reactions commonly seen in workers who face these kinds of proceedings. Finally, the article offers a set of practical psychological coping strategies and procedural recommendations for dealing with the stresses of an investigation, administrative action, or litigation, and for mitigating their effects on one's life and career.

  1. Recovery patterns, histological observations and genetic integrity in Malus shoot tips cryopreserved using droplet vitrification and encapsulation-dehydration procedures

    Science.gov (United States)

    A droplet-vitrification procedure is described for cryopreservation of Malus shoot tips. Survival patterns, recovery types, histological observations, and genetic integrity were compared for Malus shoot tips cryopreserved using this droplet-vitrification procedure and an encapsulation-dehydration pr...

  2. Management of thumb tip injuries.

    Science.gov (United States)

    Germann, Günter; Sauerbier, Michael; Rudolf, Klaus D; Hrabowski, Manuel

    2015-03-01

    The management of thumb tip injuries has undergone great changes in recent years. The traditional armamentarium of flaps has been expanded and replaced by a wide variety of flaps with more versatility and less donor side morbidity. Parallel to the development of new flaps, the conservative treatment of thumb tip injuries with semi-occlusive dressing has gained ground in the treatment of these injuries. Although tedious and time-consuming, and requiring intensive communication with the patient to explain the look and occasionally fetid smell of the wound, this technique yields excellent results with respect to restoring contour and sensibility in pulp injuries. The article gives an update on the current options for treating thumb tip injuries including the most commonly applied flaps. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  3. Nanobits: customizable scanning probe tips

    DEFF Research Database (Denmark)

    Kumar, Rajendra; Shaik, Hassan Uddin; Sardan Sukas, Özlem

    2009-01-01

    We present here a proof-of-principle study of scanning probe tips defined by planar nanolithography and integrated with AFM probes using nanomanipulation. The so-called 'nanobits' are 2-4 mu m long and 120-150 nm thin flakes of Si3N4 or SiO2, fabricated by electron beam lithography and standard...... silicon processing. Using a microgripper they were detached from an array and fixed to a standard pyramidal AFM probe or alternatively inserted into a tipless cantilever equipped with a narrow slit. The nanobit-enhanced probes were used for imaging of deep trenches, without visible deformation, wear...... or dislocation of the tips of the nanobit after several scans. This approach allows an unprecedented freedom in adapting the shape and size of scanning probe tips to the surface topology or to the specific application....

  4. ZBrush Professional Tips and Techniques

    CERN Document Server

    Gaboury, Paul

    2012-01-01

    Learn to work effectively and creatively with all versions of ZBrush! ZBrush is used by top artists in Hollywood to model and sculpt characters in such films as Avatar, Iron Man, and Pirates of the Caribbean. In addition, this amazing technology is also used in jewelry design, forensic science, aerospace, video games, toy creation, and the medical field. Written by Pixologic's in-house ZBrush expert Paul Gaboury, this full-color, beautifully illustrated guide provides you with the ultimate tips and tricks to maximize your use of all versions of ZBrush. Reveals numerous little-known tips and tr

  5. Office 2010 Visual Quick Tips

    CERN Document Server

    Gunter, Sherry Kinkoph

    2010-01-01

    Get more done in Office 2010 in less time with these Quick Tips!. Whether you're new to Microsoft Office or updating from older versions, this is the perfect resource to get you quickly up to speed on Office 2010. Every application is covered, including Word, Excel, PowerPoint, Outlook, and Publisher. Full-color screenshots and numbered steps clearly explain dozens of features and functions-while quick shortcuts, tips, and tricks help you save time and boost productivity. You'll also find great new ways to access and use some Office apps right from the Web.: Walks you through dozens of new fea

  6. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos ... limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening liver failure ...

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... in creating the TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This page ... of Use | Links | Site Map Copyright © 2018 ... To help ensure current and accurate information, we do not permit copying but encourage linking ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... liver to bypass the liver entirely, reducing high blood pressure in the portal vein and the associated risk of bleeding from enlarged veins. top of page How is the procedure performed? Image-guided, minimally invasive procedures such as a TIPS are most often ...

  9. Tipping points in ecological networks.

    Science.gov (United States)

    Tylianakis, Jason M; Coux, Camille

    2014-05-01

    Network studies have described the complex interactions among species. Concomitantly, researchers have searched for signals of ecosystem tipping points and attributes of systems that resist them. A recent study combines these areas, showing that attributes of pollination network structure delay critical transitions, and generating a wealth of new research questions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Tips for Socializing with Aphasia

    Science.gov (United States)

    ... others get comfortable Dysarthria & Apraxia - How Stroke Affects Speech Auditory Overload Aphasia vs Apraxia Reading, Writing and Math Reading Rehab ( ... number of ways. Learn more about conditions impacting speech, language, reading and writing and find tips for continuing ... 7 Types of Aphasia 8 Brain Stem Stroke 9 Cognitive Challenges After ...

  11. Library Management Tips that Work

    Science.gov (United States)

    Smallwood, Carol, Ed.

    2011-01-01

    There's no shortage of library management books out there--but how many of them actually tackle the little details of day-to-day management, the hard-to-categorize things that slip through the cracks of a larger handbook? "Library Management Tips that Work" does exactly that, addressing dozens of such issues facing library managers, including: (1)…

  12. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... Plan to stay overnight at the hospital for one or more days. What is Transjugular Intrahepatic Portosystemic Shunt (TIPS)? What are some common uses of the procedure? How should I prepare? What does the equipment look like? How does the procedure work? How is the procedure performed? What will I ...

  13. Mini-flared Kelman tip, reverse tip, and sidewinder tip with torsional phaco: a prospective randomized comparative study

    Directory of Open Access Journals (Sweden)

    Wilson Takashi Hida

    2015-02-01

    Full Text Available Purpose: To compare the efficiency of surgical procedures using three phaco tip designs in torsional phacoemulsification using the bevel-down technique. Methods: In this prospective, comparative, masked study, patients were randomly assigned to have torsional coaxial microincision cataract surgery using the mini-flared 45-degree Kelman tip, reversed mini-flared 30-degree Kelman tip, or Sidewinder 30-degree Kelman tip. Clinical measurements included preoperative and 3-month postoperative corrected distance visual acuity (CDVA, endothelial cell counts (ECC, and preoperative and 1-day postoperative central corneal thickness (CCT. Intraoperative measurements included phaco time, torsional time, aspiration time, case time, cumulative dissipated energy (CDE, and balanced salt solution volume (BSS. Results: The study evaluated 150 eyes of 150 patients. Intraoperatively, there was no statistically significant difference in cumulative dissipated energy, case time, torsional time, and aspiration time between the three tip configurations. However, less phaco time was used with the mini-flared 45-degree Kelman tip (p=0.02 than that with the Sidewinder 30-degree Kelman tip or reversed mini-flared 30-degree Kelman tip. The mini-flared 45-degree Kelman tip and the reversed mini-flared 30-degree Kelman tip required significantly less balanced salt solution volume than that required by the Sidewinder 30-degree Kelman tip (p=0.009. There was no statistically significant difference in corrected distance visual acuity and endothelial cell counts between tips 3 months postoperatively (p>0.05. Conclusion: All three tips were effective with no intraoperative complications. When using torsional phacoemulsification through microincisions and the prefracture technique with the bevel-down technique, the mini-flared 45-degree Kelman tip required a lower mean phaco time than the reversed mini-flared 30-degree Kelman tip and the Sidewinder 30-degree Kelman tip.

  14. Tips for Reducing Pesticide Impacts on Wildlife

    Science.gov (United States)

    This Web page provides tips for pesticide users in residential and agricultural settings, as well as tips for certified pesticide applicators for ways to protect wildlife from potentially harmful effects of pesticides.

  15. Helping Your Child: Tips for Parents

    Science.gov (United States)

    ... or computers. Use your children's food choices as teaching moments. Speak up when you see unhealthy eating ... Tips for Adults Health Tips for Older Adults Spanish-language publications in the Lifespan Series include the ...

  16. Parenting Tips: How to Improve Toddler Behavior

    Science.gov (United States)

    ... issues. To encourage listening and cooperation, follow these parenting tips. By Mayo Clinic Staff Life can be ... and a degree of routine. Consider these practical parenting tips. Make sure your displays of affection for ...

  17. Radiofrequency Wire Recanalization of Chronically Thrombosed TIPS

    Energy Technology Data Exchange (ETDEWEB)

    Majdalany, Bill S., E-mail: bmajdala@med.umich.edu [University of Michigan Health System, Division of Interventional Radiology, Department of Radiology (United States); Elliott, Eric D., E-mail: eric.elliott@osumc.edu [The Ohio State University Wexner Medical Center, Division of Interventional Radiology, Department of Radiology (United States); Michaels, Anthony J., E-mail: Anthony.michaels@osumc.edu; Hanje, A. James, E-mail: James.Hanje@osumc.edu [The Ohio State University Wexner Medical Center, Division of Gastroenterology and Hepatology, Department of Medicine (United States); Saad, Wael E. A., E-mail: wsaad@med.umich.edu [University of Michigan Health System, Division of Interventional Radiology, Department of Radiology (United States)

    2016-07-15

    Radiofrequency (RF) guide wires have been applied to cardiac interventions, recanalization of central venous thromboses, and to cross biliary occlusions. Herein, the use of a RF wire technique to revise chronically occluded transjugular intrahepatic portosystemic shunts (TIPS) is described. In both cases, conventional TIPS revision techniques failed to revise the chronically thrombosed TIPS. RF wire recanalization was successfully performed through each of the chronically thrombosed TIPS, demonstrating initial safety and feasibility in this application.

  18. Nasal tip sutures: Techniques and indications.

    Science.gov (United States)

    Cingi, Cemal; Muluk, Nuray Bayar; Ulusoy, Seçkin; Söken, Hakan; Altıntoprak, Niyazi; Şahin, Ethem; Ada, Servet

    2015-01-01

    The surgical anatomy of the nasal tip is determined by intrinsic factors, such as the nasal tip volume, shape, definition, and symmetry. These factors are intimately related to the morphology of the lower lateral cartilages. Tip sutures reduce the need for grafts and allow the surgeon to manipulate the tip with a high degree of precision and better long-term clinical outcomes. In this review, we evaluated common nasal tip suture techniques to clarify the similarities and differences among them. The following nasal tip suture techniques were investigated: medial crural fixation suture, middle crura suture, transdomal (dome creating, dome binding, domal definition) suture, interdomal suture, lateral crural mattress suture, columella septal suture, intercrural suture, tip rotation suture, craniocaudal transdomal suture, lateral crural spanning suture, suspension suture, tongue-in-groove technique, and lateral crural steal. Tip sutures increase tip projection, narrow the tip, provide stabilization, and provide tip rotation. The sutures may be used separately or together. Nasal tip sutures have long been used as noninvasive suture techniques. Each suture technique has unique benefits, and various key points must be considered when using these techniques.

  19. Injector tip for an internal combustion engine

    Science.gov (United States)

    Shyu, Tsu Pin; Ye, Wen

    2003-05-20

    This invention relates to a the tip structure of a fuel injector as used in a internal combustion engine. Internal combustion engines using Homogeneous Charge Compression Ignition (HCCI) technology require a tip structure that directs fuel spray in a downward direction. This requirement necessitates a tip design that is capable of withstanding mechanical stresses associated with the design.

  20. Direct calculation of wind turbine tip loss

    DEFF Research Database (Denmark)

    Wood, D.H.; Okulov, Valery; Bhattacharjee, D.

    2016-01-01

    The usual method to account for a finite number of blades in blade element calculations of wind turbine performance is through a tip loss factor. Most analyses use the tip loss approximation due to Prandtl which is easily and cheaply calculated but is known to be inaccurate at low tip speed ratio...

  1. Association of TIP30 expression and prognosis of hepatocellular carcinoma in patients with HBV infection.

    Science.gov (United States)

    Zhang, Xia; Lv, Lizhi; Ouyang, Xuenong; Zhang, Shi'an; Fang, Jian; Cai, Lirong; Li, Dongliang

    2016-09-01

    Altered expression of TIP30, a tumor suppressor, has been observed in many cancers. In this study, we have evaluated the expression of TIP30 in the tissues of 209 hepatocellular carcinomas (HCC) and their adjacent tissues by using a high-density tissue microarray, and analyzed its correlation with the clinical pathological parameters of the patients. The results revealed negative or weak expression of TIP30 in 43.5% (91/209) of the HCC tissues, and in only 27% (56/209) of the adjacent tissues. The expression level of TIP30 in HCC was inversely correlated with serum alpha-fetoprotein (AFP) levels, HBV infection, and tumor differentiation. Multivariate analysis for survival indicated that serum HBV infection was the most significant predictor of poor prognosis in HCC (P = 0.0023), and TIP30 expression and tumor differentiation were also independent indicators in this respect (P = 0.0364 and P = 0.0397, respectively). Patients with medium or high expression levels of TIP30 (TIP30(++/+++) ) had a better 5-year overall survival rate than those with low/negative (TIP30(+/-) ) expression (P HBV(+) patients had the worst 5-year overall survival rate, whereas TIP30(++/+++) /HBV(-) patients had the best. To further explore the correlation between TIP30 and HBV infection in HCC, HBV(+) hepatoblastoma cell-line HepG2 2.2.15 and HCC cell-line Hep3B were used. Upon silencing of HBV, we observed an upregulation of TIP30 and decreased cell proliferation. In the in vivo studies, we found that the mice inoculated with HepG2 2.2.15 cells with HBV silencing had a prolonged tumor latency and a longer life span, as compared to the control mice inoculated with untreated control cells. In conclusion, the results suggest that downregulation of TIP30 may result from HBV infection, and subsequently promotes the progression of HCC. © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  2. Pro Photo Tips: For Students

    OpenAIRE

    Scott, Grant

    2014-01-01

    Pro Photo Tips: For Students has been specifically created for students studying photography at school, college or university. \\ud \\ud Each film is presented by photographer and university lecturer Grant Scott who brings his thirty years experience of working with professional photography and photographers to each area of photographic practice he discuss's. Using simple to understand language he gives you the information and inspiration you need to succeed in your studies and create a future ...

  3. Comparison of Various Supersonic Turbine Tip Designs to Minimize Aerodynamic Loss and Tip Heating

    Science.gov (United States)

    Shyam, Vikram; Ameri, Ali

    2012-01-01

    The rotor tips of axial turbines experience high heat flux and are the cause of aerodynamic losses due to tip clearance flows, and in the case of supersonic tips, shocks. As stage loadings increase, the flow in the tip gap approaches and exceeds sonic conditions. This introduces effects such as shock-boundary layer interactions and choked flow that are not observed for subsonic tip flows that have been studied extensively in literature. This work simulates the tip clearance flow for a flat tip, a diverging tip gap and several contoured tips to assess the possibility of minimizing tip heat flux while maintaining a constant massflow from the pressure side to the suction side of the rotor, through the tip clearance. The Computational Fluid Dynamics (CFD) code GlennHT was used for the simulations. Due to the strong favorable pressure gradients the simulations assumed laminar conditions in the tip gap. The nominal tip gap width to height ratio for this study is 6.0. The Reynolds number of the flow is 2.4 x 10(exp 5) based on nominal tip width and exit velocity. A wavy wall design was found to reduce heat flux by 5 percent but suffered from an additional 6 percent in aerodynamic loss coefficient. Conventional tip recesses are found to perform far worse than a flat tip due to severe shock heating. Overall, the baseline flat tip was the second best performer. A diverging converging tip gap with a hole was found to be the best choice. Average tip heat flux was reduced by 37 percent and aerodynamic losses were cut by over 6 percent.

  4. Quick-Connect Windowed Non-Stick Penetrator Tips for Rapid Sampling

    Science.gov (United States)

    Sherritt, Stewart; Jones, Jack A.; Badescu, Mircea

    2009-01-01

    Standard penetrator sampling systems were designed in order to allow for sampling via penetrators to produce a full set of sample acquisitions including volatile liquids, fine powders, and solid fragments. A gravity harpoon sampler has been designed with a removable tip and a quick coupling. The separation allows for sample handling and eliminates sample cross-contamination. Also, this design allows for multiple use of the penetrator body, which is the largest and heaviest part of the penetrator, while allowing for multiple changes of the light-mass, penetrator tip to avoid sample cross-contamination. The penetrator tip design has been improved by adding a spring trap to retain the sample, as well as a means for connecting to a quick coupling. Quick connect tips have been demonstrated in a sample handling carousel. The penetrator was released and rewound and the tips were released into a circular platter for rotation into instrument stations. The pyro-harpoon sampler was fabricated and tested with a NASA Standard Initiator (NSI) pyrotechnic charge. Initial tests collected cryogenic ice, but removal of the small pyro-harpoon from the ice was difficult. A brass metal sheath was then fitted over the harpoon tip, and removal from the ice was greatly alleviated by leaving the sheath in the ice. Quartz windows in the tips allow direct optical and spectral imaging and gas chromatography-mass spectrometer (GCMS) pyrolysis, and were found to survive impact. All systems were successfully tested by dropping into sand and into cryogenic ice.

  5. Anbar Awakens: The Tipping Point

    Science.gov (United States)

    2008-04-01

    CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ...ORGANIZATION NAME(S) AND ADDRESS(ES) Army Combined Arms Center,Army & Marine CounterInsurgency Center (COIN),Fort Leavenworth,KS,66027 8. PERFORMING ...radical change, or a “tipping point,” to occur: mavens, salespersons , and connectors. in brief, mavens have the goods, salespersons spread the word, and

  6. Nail photography: Tips and tricks

    Directory of Open Access Journals (Sweden)

    Feroze Kaliyadan

    2016-01-01

    Full Text Available Photographic documentation of the nails is important in the objective evaluation of response to treatment and in disseminating scientific information related to nail diseases. The key to a good image of the nail is proper framing and achieving a sharp focused image with good contrast with the background, at the same time avoiding strong reflections from the nail surface. While the general principles of clinical photography apply to nail imaging also, this article attempts to highlight some tips which can be specifically used to improve the quality of nail images.

  7. Nail Photography: Tips and Tricks.

    Science.gov (United States)

    Kaliyadan, Feroze; Ashique, K T

    2016-01-01

    Photographic documentation of the nails is important in the objective evaluation of response to treatment and in disseminating scientific information related to nail diseases. The key to a good image of the nail is proper framing and achieving a sharp focused image with good contrast with the background, at the same time avoiding strong reflections from the nail surface. While the general principles of clinical photography apply to nail imaging also, this article attempts to highlight some tips which can be specifically used to improve the quality of nail images.

  8. Windows 8 visual quick tips

    CERN Document Server

    McFedries, Paul

    2012-01-01

    Easy-in, easy-out format covers all the bells and whistles of Windows 8 If you want to learn how to work smarter and faster in Microsoft's Windows 8 operating system, this easy-to-use, compact guide delivers the goods. Designed for visual learners, it features short explanations and full-color screen shots on almost every page, and it's packed with timesaving tips and helpful productivity tricks. From enhancing performance and managing digital content to setting up security and much more, this handy guide will help you get more out of Windows 8. Uses full-color screen shots and short, step-by-

  9. Tipping elements in the Earth's climate system.

    Science.gov (United States)

    Lenton, Timothy M; Held, Hermann; Kriegler, Elmar; Hall, Jim W; Lucht, Wolfgang; Rahmstorf, Stefan; Schellnhuber, Hans Joachim

    2008-02-12

    The term "tipping point" commonly refers to a critical threshold at which a tiny perturbation can qualitatively alter the state or development of a system. Here we introduce the term "tipping element" to describe large-scale components of the Earth system that may pass a tipping point. We critically evaluate potential policy-relevant tipping elements in the climate system under anthropogenic forcing, drawing on the pertinent literature and a recent international workshop to compile a short list, and we assess where their tipping points lie. An expert elicitation is used to help rank their sensitivity to global warming and the uncertainty about the underlying physical mechanisms. Then we explain how, in principle, early warning systems could be established to detect the proximity of some tipping points.

  10. Addressing Tipping Points for a Precarious Future

    OpenAIRE

    O'Riordan, Timothy; Lenton, Timothy

    2013-01-01

    This book places tipping points in their scientific, economic, governmental, creative, and spiritual contexts. It seeks to offer a comprehensive set of interpretations on the meaning and application of tipping points. Its contribution focuses on the various characterisations and metaphors of tipping points, on the scope for anticipating their onset, the capacity for societal resilience in the face of their impending arrival, and for better ways of communicating and preparing societies, econom...

  11. Control of lethal browning by using ascorbic acid on shoot tip ...

    African Journals Online (AJOL)

    The use of ascorbic acid during explants preparation and the effect of different concentrations of ascorbic acid in controlling lethal browning and survival of the explants in local banana cv. Mzuzu banana were investigated. The explants were taken from young suckers. The shoot tips were cultured on Murashige and Skoog's ...

  12. Is there a magnitude effect in tipping?

    Science.gov (United States)

    Green, Leonard; Myerson, Joel; Schneider, Rachel

    2003-06-01

    The present study examined nearly 1,000 tips recorded for two taxicabs, two hair salons, and two restaurants. In each of the six cases, amount of tip increased linearly as a function of the amount of the bill. Contrary to standard microeconomic theory, there was a magnitude effect in that as the amount of the bill increased, the percent tip tended to decrease. The present results extend the findings of Chapman and Winquist (1998), obtained using hypothetical scenarios, to real-world tipping behavior. Chapman and Winquist argued that a magnitude effect in tipping reflects the shape of the utility function for money. We suggest, however, that the magnitude effect may be the mathematical consequence of replotting the fundamental relationship between tip and bill amounts in terms of percent tip, given that the observed linear relation between tip and bill amounts has a positive intercept. We suggest further that the positive intercept arises because a tip represents a judgment as to what constitutes a fair or equitable wage, and part of what constitutes a fair wage is independent of the amount of the bill, reflecting compensation for simply being there when needed. The present account implies that different explanations may be needed for magnitude effects observed in different domains.

  13. Micropropagation of Cyrtopodium paludicolum (Orchidaceae from root tip explants

    Directory of Open Access Journals (Sweden)

    Dayana Rotili Nunes Picolotto

    2017-06-01

    Full Text Available An efficient protocol for in vitro plant propagation of Cyrtopodium paludicolum has been developed using root tips dissected from well-developed seedlings. Root tips were cultured on Knudson medium supplemented with α-naphthaleneacetic acid (NAA, and/or thidiazuron (TDZ. TDZ did not induce protocorm-like bodies (PLBs in the NAA absence, indicating phytoregulators synergistic effect. Medium supplemented with 1.34 μM NAA and 2.27 μM TDZ resulted in better response on PBLs, and subsequent shoot differentiation (55.25 shoots per explant, and in better rooting number and root length responses, favoring acclimatization with 90% of survived plants. However, the medium supplemented with only NAA (1.34 μM resulted in 33.50 shoots per explant. Histological sections confirmed that only one PLB was induced per responsive root tip, and it showed numerous dispersed and extended meristemoids, or division centers that originated new PBLs. Additionally, this protocol could be an excellent model to study molecular aspects of root to shoot conversion.

  14. The tip of the iceberg

    DEFF Research Database (Denmark)

    Bjørst, Lill Rastad

    2010-01-01

      Abstract: The tip of the iceberg: Ice as a nonhuman actor of the climate change debate   The global climate change debate has the Arctic as a core region of concern and ice has become a central aspect of discourses. This article discusses ice representations from six different contexts linked...... to the 2009 United Nations Climate Change Conference (COP15) in Copenhagen. The author argues that even though the discussions often seem to be centred on ice alone, the latter gets inscribed in narratives and metaphors which have wider implications for how the Arctic and its Indigenous peoples...... are represented. Ice becomes a nonhuman actor, framing the discussions, acting in specific ways, and linking hybrid networks. Indeed it is used in diverse platforms by scientists, politicians, governments, NGOs, as well as Inuit hunters and fishermen...

  15. Lateral Tip Control Effects in CD-AFM Metrology: The Large Tip Limit.

    Science.gov (United States)

    Dixson, Ronald G; Orji, Ndubuisi G; Goldband, Ryan S

    2016-01-25

    Sidewall sensing in critical dimension atomic force microscopes (CD-AFMs) usually involves continuous lateral dithering of the tip or the use of a control algorithm and fast response piezo actuator to position the tip in a manner that resembles touch-triggering of coordinate measuring machine (CMM) probes. All methods of tip position control, however, induce an effective tip width that may deviate from the actual geometrical tip width. Understanding the influence and dependence of the effective tip width on the dither settings and lateral stiffness of the tip can improve the measurement accuracy and uncertainty estimation for CD-AFM measurements. Since CD-AFM typically uses tips that range from 15 nm to 850 nm in geometrical width, the behavior of effective tip width throughout this range should be understood. The National Institute of Standards and Technology (NIST) has been investigating the dependence of effective tip width on the dither settings and lateral stiffness of the tip, as well as the possibility of material effects due to sample composition. For tip widths of 130 nm and lower, which also have lower lateral stiffness, the response of the effective tip width to lateral dither is greater than for larger tips. However, we have concluded that these effects will not generally result in a residual bias, provided that the tip calibration and sample measurement are performed under the same conditions. To validate that our prior conclusions about the dependence of effective tip width on lateral stiffness are valid for large CD-tips, we recently performed experiments using a very large non-CD tip with an etched plateau of approximately 2 μm width. The effective lateral stiffness of these tips is at least 20 times greater than typical CD-AFM tips, and these results supported our prior conclusions about the expected behavior for larger tips. The bottom-line importance of these latest observations is that we can now reasonably conclude that a dither slope of 3 nm

  16. Tips for Postpartum Dads and Partners

    Science.gov (United States)

    ... Online Training Tools for Mom Frequently Asked Questions Screening Recommendations Useful Links Media Family International Father’s Mental Health Day Dads for World Maternal Mental Health Day ...

  17. Summer Safety Tips - Staying Safe Outdoors

    Science.gov (United States)

    ... following these tips from the American Academy of Pediatrics (AAP). Also, see Summer Safety Tips: Sun and Water Safety ​ for more information. Fireworks Safety​​ Fireworks can result in severe burns , blindness, scars, and even death. Fireworks that are ...

  18. The Tipping Point in School Culture

    Science.gov (United States)

    Nelsen, Jeff; Hill, Bob

    2009-01-01

    Once changes or innovations reach the tipping point, they spread throughout an organization and become entrenched as part of the culture, becoming "just the way we do things around here." These authors see the tipping point at play with systemic improvement in two urban school districts with which they have worked. Here, they describe…

  19. News: Tripping over tipping points/elements

    Science.gov (United States)

    The term “tipping point” has been used to identify a critical threshold susceptible to a tiny perturbation that can qualitatively alter the state or development of a system. “Tipping element” has been introduced to describe large-scale components of the Earth system that may pass...

  20. Tips for Good Oral Health during Pregnancy

    Science.gov (United States)

    Tips for Good Oral Health During Pregnancy B elow are tips for taking care of your oral health while you are pregnant. Getting ... Dental Association. http: / / www. ada. org/ 993. aspx. Good Oral Health for Two (handout) produced by the Northeast Center ...

  1. Economics of tipping the climate dominoes

    Science.gov (United States)

    Lemoine, Derek; Traeger, Christian P.

    2016-05-01

    Greenhouse gas emissions can trigger irreversible regime shifts in the climate system, known as tipping points. Multiple tipping points affect each other’s probability of occurrence, potentially causing a `domino effect’. We analyse climate policy in the presence of a potential domino effect. We incorporate three different tipping points occurring at unknown thresholds into an integrated climate-economy model. The optimal emission policy considers all possible thresholds and the resulting interactions between tipping points, economic activity, and policy responses into the indefinite future. We quantify the cost of delaying optimal emission controls in the presence of uncertain tipping points and also the benefit of detecting when individual tipping points have been triggered. We show that the presence of these tipping points nearly doubles today’s optimal carbon tax and reduces peak warming along the optimal path by approximately 1 °C. The presence of these tipping points increases the cost of delaying optimal policy until mid-century by nearly 150%.

  2. Atraumatic suction tip for microsurgery: technical note.

    NARCIS (Netherlands)

    Menovsky, T.; Vries, J. de

    2004-01-01

    During microneurosurgery, frequent suction is essential for a successful operative course. A new self-made disposable suction tip is described which facilitates atraumatic suction, even near vital anatomical structures. The efficacy of this suction tip was confirmed in selected operative procedures.

  3. Tips to Help You Get Active

    Science.gov (United States)

    ... A Guide for Teenagers Talking with Patients about Weight Loss: Tips for Primary Care Providers Tips to Help You Get Active Benefits Starting Physical Activity Keep Moving Clinical Trials Understanding Adult Overweight and Obesity Using the World Around You to Stay Healthy ...

  4. Mental Illness

    Science.gov (United States)

    ... leading cause of disability. Untreated mental illness can cause severe emotional, behavioral and physical health problems. Complications sometimes linked to mental illness include: Unhappiness and decreased enjoyment of life ...

  5. Mental Health

    Science.gov (United States)

    Mental health includes our emotional, psychological, and social well-being. It affects how we think, feel and act as ... stress, relate to others, and make choices. Mental health is important at every stage of life, from ...

  6. Mental Disorders

    Science.gov (United States)

    Mental disorders include a wide range of problems, including Anxiety disorders, including panic disorder, obsessive-compulsive disorder, ... disorders, including schizophrenia There are many causes of mental disorders. Your genes and family history may play ...

  7. Molecular Mechanics of Tip-Link Cadherins

    Science.gov (United States)

    Sotomayor, Marcos; Weihofen, Wilhelm A.; Gaudet, Rachelle; Corey, David P.

    2011-11-01

    The hair-cell tip link, a fine filament directly conveying force to mechanosensitive transduction channels, is likely composed of two proteins, protocadherin-15 and cadherin-23, whose mutation causes deafness. However, their complete molecular structure, elasticity, and deafness-related structural defects remain largely unknown. We present crystal structures of extracellular (EC) tip-link cadherin repeats involved in hereditary deafness and tip link formation. In addition, we show that the deafness mutation D101G, in the linker region between the repeats EC1 and EC2 of cadherin-23, causes a slight bend between repeats and decreases Ca2+ affinity. Molecular dynamics simulations suggest that tip-link cadherin repeats are stiff and that either removing Ca2+ or mutating Ca2+-binding residues reduces rigidity and unfolding strength. The structures and simulations also suggest mechanisms underlying inherited deafness and how cadherin-23 may bind with protocadherin-15 to form the tip link.

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS Migration to the Heart Diagnosed by Emergency Department Ultrasound

    Directory of Open Access Journals (Sweden)

    Carlan Wendler

    2012-12-01

    Full Text Available A 57-year-old man presented to our emergency department with altered mental status. He had a past medical history significant for cirrhosis and previous placement of a transjugular intrahepatic portosystemic shunt (TIPS. On cardiac auscultation, a new heart murmur and an unexpected degree of cardiac ectopy were noted. On the 12-lead electrocardiogram, the patient was noted to have multiple premature atrial contractions, corroborating the irregular heart rhythm on physical exam. A focused bedside emergency ultrasound of the heart was then performed. This exam revealed an apparent foreign body in the right atrium. It appeared as if the patient’s TIPS had migrated from the heart into the right atrium. This case, as well as the literature describing thisunusual complication of TIPS placement, is reviewed in this case report

  9. Mapa Mental

    OpenAIRE

    do Couto, Hildo Honório

    2017-01-01

    O objetivo principal deste artigo é mostrar que no interior do ecossistema mental da língua, e do nosso ecossistema cognitivo geral, existe uma parte que se pode chamar de mapa mental, intimamente associado ao mapa cognitivo. Após caracterizar o conceito de mapa mental e de associá-lo a conceitos assemelhados, comento o mapa mental que eu tinha de Brasília, por ter vivido lá por mais de 30 anos. Como me mudei para Goiânia, comecei a perder partes do mapa mental de Brasília. Por outro lado, es...

  10. Numerical investigation of three wind turbine blade tips

    DEFF Research Database (Denmark)

    Johansen, J.; Sørensen, Niels N.

    2002-01-01

    of attack is presented and further analysis is performed on lift and drag coefficients. It is shown that the original Standard tip results in a more concentrated tip vortex leading to a steeper gradient on bothtangential and normal forces when approaching the tip, whereas the two tapered tips show a more....... The Taper tip keeps the higher loading causing the flapwise bending moment to be higher as seen inmeasurements. To determine the radial variation of lift and drag coefficients the local inflow angle of attack is determined. It is shown that the Standard tip experiences a slightly larger angle of attack...... at the tip compared to the two tapered tips. Thelift coefficients are kept at a more constant level for the two tapered tips due to the decrease in chord, while the drag coefficients actually decrease for the two tapered tips, especially for the Swept tip. For the Swept tip at 12 m/s both lift...

  11. Healthy Eating for Vegetarians: 10 Tips for Vegetarians

    Science.gov (United States)

    ... Guidelines Communicator’s Guide 10 Tips: Healthy Eating for Vegetarians You are here Home 10 Tips: Healthy Eating ... Vegetarians Print Share 10 Tips: Healthy Eating for Vegetarians A vegetarian eating pattern can be a healthy ...

  12. Mapping cavitation activity around dental ultrasonic tips.

    Science.gov (United States)

    Walmsley, A Damien; Lea, Simon C; Felver, Bernhard; King, David C; Price, Gareth J

    2013-05-01

    Cavitation arising within the water around the oscillating ultrasonic scaler tip is an area that may lead to advances in enhancing biofilm removal. The aim of this study is to map the occurrence of cavitation around scaler tips under loaded conditions. Two designs of piezoelectric ultrasonic scaling probes were evaluated with a scanning laser vibrometer and luminol dosimetric system under loaded (100 g/200 g) and unloaded conditions. Loads were applied to the probe tips via teeth mounted in a load-measuring apparatus. There was a positive correlation between probe displacement amplitude and cavitation production for ultrasonic probes. The position of cavitation at the tip of each probe was greater under loaded conditions than unloaded and for the longer P probe towards the tip. Whilst increasing vibration displacement amplitude of ultrasonic scalers increases the occurrence of cavitation, factors such as the length of the probe influence the amount of cavitation activity generated. The application of load affects the production of cavitation at the most clinically relevant area-the tip. Loading and the design of ultrasonic scalers lead to maximising the occurrence of the cavitation at the tip and enhance the cleaning efficiency of the scaler.

  13. Compressor Stability Enhancement Using Discrete Tip Injection

    Science.gov (United States)

    Suder, Kenneth L.; Hathaway, Michael D.; Thorp, Scott A.; Strazisar, Anthony J.; Bright, Michelle B.

    2001-01-01

    Mass injection upstream of the tip of a high-speed axial compressor rotor is a stability enhancement approach known to be effective in suppressing small in tip-critical rotors. This process is examined in a transonic axial compressor rotor through experiments and time-averaged Navier-Stokes CFD simulations. Measurements and simulations for discrete injection are presented for a range of injection rates and distributions of injectors around the annulus. The simulations indicate that tip injection increases stability by unloading the rotor tip and that increasing injection velocity improves the effectiveness of tip injection. For the tested rotor, experimental results demonstrate that at 70 percent speed the stalling flow coefficient can be reduced by 30 percent using an injected mass- flow equivalent to 1 percent of the annulus flow. At design speed, the stalling flow coefficient was reduced by 6 percent using an injected mass-fiow equivalent to 2 percent of the annulus flow. The experiments show that stability enhancement is related to the mass-averaged axial velocity at the tip. For a given injected mass-flow, the mass-averaged axial velocity at the tip is increased by injecting flow over discrete portions of the circumference as opposed to full-annular injection. The implications of these results on the design of recirculating casing treatments and other methods to enhance stability will be discussed.

  14. [Suture tip plasty using an endonasal approach].

    Science.gov (United States)

    Tasman, A-J; Palma, P

    2010-09-01

    Over the last two decades, the use of the external approach for primary and secondary rhinoplasties has become increasingly popular. This article illustrates the versatility of endonasal techniques for the correction of nasal tip deformities on the basis of four cases. The approach to the nasal tip and the chosen technique as used in 100 consecutive rhinoplasties were reviewed. For primary and revision tip plasty, endonasal approaches were used in 81% of cases. Preferred incisions were the infracartilaginous approach and the transfixion incision. Using these approaches, correction of the tip was achieved by using sutures to reposition and reshape the alar cartilages and the columella without grafts to the nasal tip in most cases. Nasal tip plasty via endonasal approaches using sutures is technically more challenging compared to the external approach with its superior exposure. This drawback is outweighed by less operating time and faster patient recovery. Contrary to the general trend, the authors believe that endonasal tip plasty techniques using sutures can obviate the external approach and grafts in many cases and should form an integral part of the rhino-surgeon's repertoire.

  15. Survival Analysis

    CERN Document Server

    Miller, Rupert G

    2011-01-01

    A concise summary of the statistical methods used in the analysis of survival data with censoring. Emphasizes recently developed nonparametric techniques. Outlines methods in detail and illustrates them with actual data. Discusses the theory behind each method. Includes numerous worked problems and numerical exercises.

  16. Modelling survival

    DEFF Research Database (Denmark)

    Ashauer, Roman; Albert, Carlo; Augustine, Starrlight

    2016-01-01

    well GUTS, calibrated with short-term survival data of Gammarus pulex exposed to four pesticides, can forecast effects of longer-term pulsed exposures. Thirdly, we tested the ability of GUTS to estimate 14-day median effect concentrations of malathion for a range of species and use these estimates...

  17. Development of apertureless near-field scanning optical microscope tips for tip-enhanced Raman spectroscopy.

    Science.gov (United States)

    Kodama, T; Umezawa, T; Watanabe, S; Ohtani, H

    2008-02-01

    In this study, we suggested two types of novel metallized tip for the apertureless near-field scanning optical microscope probe. The first is a silver nanorod immobilized tip and the other is a double metallized probe. We calculated the electric field enhancement factor and the electric field distribution of a single sphere, aggregated spheres, an ellipse and a nanorod by the finite-differential time-domain method to improve the silver nanosphere immobilized tip developed in our previous studies. The enhanced field of the nanorod is localized at the external surfaces. The simulation results of the nanorod revealed that the position of the maximum peak is shifted to a longer wavelength and that its electric field enhancement factor increases as the aspect ratio increases. Thus, we developed the silver nanorod immobilized tip, and the tip-enhanced Raman spectrum of rhodamine 6G molecule on the substrate could be measured by the tip though it could not be detected by the previous nanosphere immobilized tip. Further, the finite-differential time-domain calculation predicted that the double metallized tips considerably enhance the electric field and that its enhancement factor in the longer wavelength region (500-600 nm) does not decrease when the tip is rounded. The results show that the proposed metallized tips were useful for the apertureless near-field scanning optical microscope system.

  18. CFD analysis of cloud cavitation on three tip-modified propellers with systematically varied tip geometry

    Science.gov (United States)

    Shin, K. W.; Andersen, P.

    2015-12-01

    The blade tip loading is often reduced as an effort to restrain sheet and tip vortex cavitation in the design of marine propellers. This CFD analysis demonstrates that an excessive reduction of the tip loading can cause cloud cavitation responsible for much of noise and surface erosion. Detached eddy simulations (DES) are made for cavitating flows on three tip- modified propellers, of which one is a reference propeller having an experimental result from a cavitation tunnel test with a hull model, and the other two are modified from the reference propeller by altering the blade tip loading. DES results have been validated against the experiment in terms of sheet and cloud cavitation. In DES, non-uniform hull wake is modelled by using the inlet flow and momentum sources instead of including a hull model. A 4-bladed Kappel propeller with a smooth tip bending towards the suction side is used as the reference propeller. For the reference propeller, sheet cavitation extends over a whole chord length in the hull wake peak. As the blade gets out of the wake peak, the rear part of sheet cavity is detached in a form of cloud cavitation. For the reference propeller, the tip pitch reduction from the maximum is about 35%. When decreasing the tip pitch reduction to 10%, tip vortex cavitation is formed and cloud cavitation is significantly weakened. When increasing the tip pitch reduction to 60%, sheet cavitation slightly moves to inner radii and cloud cavitation grows larger.

  19. Why pay extra? Tipping and the importance of social norms and feelings in economic theory

    OpenAIRE

    Azar, Ofer H.

    2005-01-01

    Tipping is a multi-billion-dollar phenomenon that standard economic models find hard to explain. I discuss several aspects of tipping and divide tipping to six different categories: reward-tipping, price- tipping, tipping-in-advance, bribery-tipping, holiday-tipping and gift- tipping, and discuss the economics of each category. Often tipping has economic justification, because it solves some inefficiency and increases welfare. Analyzing the potential reasons for tipping illustrates the import...

  20. Impetigo: Tips for Treatment and Prevention

    Science.gov (United States)

    ... DO Videos Contact Close ‹ Back to Healthy Living Impetigo: Tips for Treatment and Prevention The symptoms of ... to other parts of their bodies. Causes of Impetigo Impetigo usually affects preschool and school-aged children, ...

  1. Get Moving: Easy Tips to Get Active!

    Science.gov (United States)

    ... Preschoolers Infographic How to Make a Healthy Home Dietary Recommendations for Healthy Children Top 10 Tips to Help Children Develop Healthy Habits Fruit and Veggie Toolkit for Kids Healthy Foods ...

  2. Compressor airfoil tip clearance optimization system

    Science.gov (United States)

    Little, David A.; Pu, Zhengxiang

    2015-08-18

    A compressor airfoil tip clearance optimization system for reducing a gap between a tip of a compressor airfoil and a radially adjacent component of a turbine engine is disclosed. The turbine engine may include ID and OD flowpath boundaries configured to minimize compressor airfoil tip clearances during turbine engine operation in cooperation with one or more clearance reduction systems that are configured to move the rotor assembly axially to reduce tip clearance. The configurations of the ID and OD flowpath boundaries enhance the effectiveness of the axial movement of the rotor assembly, which includes movement of the ID flowpath boundary. During operation of the turbine engine, the rotor assembly may be moved axially to increase the efficiency of the turbine engine.

  3. Time and project management tips for educators.

    Science.gov (United States)

    Shellenbarger, Teresa

    2009-07-01

    As work demands increase, educators need to manage time and work projects effectively. This column provides guidelines and tips that continuing education and staff development professionals in all settings can use to take control of time and work projects.

  4. Time for Some Summer Sun Safety Tips

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_166721.html Time for Some Summer Sun Safety Tips Pediatricians offer ... isn't there. Summertime often means more unsupervised time Be aware that changes in your routine might ...

  5. Back-to-School Health Tips: Immunizations

    Science.gov (United States)

    ... JavaScript on. Feature: Back-to-School Health Tips: Immunizations Past Issues / Fall 2014 Table of Contents Your ... eating healthy lunches and snacks. Check-Ups and Immunizations It's a good idea to take your child ...

  6. Impetigo: Tips for Treatment and Prevention

    Science.gov (United States)

    ... to Healthy Living Impetigo: Tips for Treatment and Prevention The symptoms of impetigo are honey-colored, crusty ... or anything that person has touched. Treatment and Prevention Even though impetigo is not dangerous, complications can ...

  7. Tips to Manage Anxiety and Stress

    Science.gov (United States)

    ... Contact ADAA Public Tips to Manage Anxiety and Stress When you're feeling anxious or stressed, the ... OCD, PTSD, and related disorders. Find a Therapist Stress Relief Kits Feeling stressed? Get an ADAA stress ...

  8. Tips for Teens with Diabetes: About Diabetes

    Science.gov (United States)

    National Diabetes Education Program (NDEP), 2010

    2010-01-01

    Diabetes is a serious disease. It means that one's blood glucose, also called blood sugar, is too high. Having too much glucose in a person's blood is not healthy. This paper offers tips for managing diabetes.

  9. Food Safety Tips for College Students

    Science.gov (United States)

    ... Standard Forms FSIS United States Department of Agriculture Food Safety and Inspection Service About FSIS District Offices ... Web Content Viewer (JSR 286) Actions ${title} Loading... Food Safety Tips for College Students When students pack ...

  10. Essential Outdoor Sun Safety Tips for Winter

    Science.gov (United States)

    ... Weekend Warriors expand/collapse Vitamin D Essential Outdoor Sun Safety Tips for Winter Winter sports enthusiasts are ... skiing! Be Mindful of Time Spent in the Sun, Regardless of the Season If possible, ski early ...

  11. Health Tip: Know Your Risk for Obesity

    Science.gov (United States)

    ... 166114.html Health Tip: Know Your Risk for Obesity Here's what makes it more likely To use ... Diana Kohnle Wednesday, May 31, 2017 (HealthDay News) -- Obesity is linked to an increased risk for heart ...

  12. Alzheimer's: 7 Tips for Medical Visits

    Science.gov (United States)

    ... Regular medical care is an important part of Alzheimer's treatment. Use these seven tips to stay on ... Clinic staff People who have dementia due to Alzheimer's disease need regular medical care to address a ...

  13. Quick Tips Guide for Small Manufacturing Businesses

    Science.gov (United States)

    Small manufacturing businesses can use this Quick Tips Guide to be better prepared for future extreme weather events. This guide discusses keeping good records, improving housekeeping procedures, and training employees.

  14. Children Health Tips in Other Languages

    Science.gov (United States)

    These tips for protecting children from environmental risks/exposures are available in spanish, chinese, vietnamese, and korean. They cover topics such as lead, pesticides, carbon monoxide, air pollution, drinking water contaminants, and radon.

  15. Barbecue Basics: Tips to Prevent Foodborne Illness

    Medline Plus

    Full Text Available ... Home For Consumers Consumer Updates Barbecue Basics: Tips to Prevent Foodborne Illness Share Tweet Linkedin Pin it ... are a lot of steps consumers can take to keep family and friends from becoming ill,” says ...

  16. Sleep Tips: 7 Steps to Better Sleep

    Science.gov (United States)

    ... turn every night. Consider simple tips for better sleep, from setting a sleep schedule to including physical activity in your daily ... factors that can interfere with a good night's sleep — from work stress and family responsibilities to unexpected ...

  17. Can't sleep? Try these tips

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000853.htm Can't sleep? Try these tips To use the sharing ... with your daily activities. References Adams SK, Kisler TS. Sleep quality as a mediator between technology-related ...

  18. CFD analysis of cloud cavitation on three tip-modified propellers with systematically varied tip geometry

    DEFF Research Database (Denmark)

    Shin, K. W.; Andersen, Poul

    2015-01-01

    The blade tip loading is often reduced as an effort to restrain sheet and tip vortex cavitation in the design of marine propellers. This CFD analysis demonstrates that an excessive reduction of the tip loading can cause cloud cavitation responsible for much of noise and surface erosion. Detached...... eddy simulations (DES) are made for cavitating flows on three tip- modified propellers, of which one is a reference propeller having an experimental result from a cavitation tunnel test with a hull model, and the other two are modified from the reference propeller by altering the blade tip loading. DES...... results have been validated against the experiment in terms of sheet and cloud cavitation. In DES, non-uniform hull wake is modelled by using the inlet flow and momentum sources instead of including a hull model. A 4-bladed Kappel propeller with a smooth tip bending towards the suction side is used...

  19. Learn About Mental Health

    Science.gov (United States)

    ... this? Submit What's this? Submit Button Learn About Mental Health Recommend on Facebook Tweet Share Compartir Mental Health Basics Types of Mental Illness Fast Facts Mental Health Basics What is mental illness? Mental illnesses are ...

  20. The Give and Take on Restaurant Tipping

    OpenAIRE

    Parrett, Matthew Barton

    2003-01-01

    This dissertation examines aspects of both the consumer (the "give") and the server (the "take") sides of restaurant tipping. On the consumer side, I address both why, and how much, people tip in restaurants. I also examine a policy issue related to the recent Supreme Court decision in United States v. Fior d'Italia. These issues are addressed via a combination of theoretical, empirical, and experimental analysis. On the server side, I use survey data collected from several restaurants...

  1. Mental models

    OpenAIRE

    Marco Antonio Moreira

    1996-01-01

    The mental models subject is presented particularly in the light of Johnson-Laird’s theory. Views from different authors are also presented but the emphasis lies in Johson-Laird’s approach, proposing mental models as a third path in the images x propositions debate. In this perspective, the nature, content, and typology of mental models are discussed, as well as the issue of conciousness and computability. In addition, the methodology of research studies are provided. Essentially, the aim of ...

  2. Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.

    Directory of Open Access Journals (Sweden)

    Katie Bentley

    2009-10-01

    Full Text Available Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF. Tip cells meet and fuse (anastomosis to form blood-flow supporting loops. Tip cell selection is achieved by Dll4-Notch mediated lateral inhibition resulting, under normal conditions, in an interleaved arrangement of tip and non-migrating stalk cells. Previously, we showed that the increased VEGF levels found in many diseases can cause the delayed negative feedback of lateral inhibition to produce abnormal oscillations of tip/stalk cell fates. Here we describe the development and implementation of a novel physics-based hierarchical agent model, tightly coupled to in vivo data, to explore the system dynamics as perpetual lateral inhibition combines with tip cell migration and fusion. We explore the tipping point between normal and abnormal sprouting as VEGF increases. A novel filopodia-adhesion driven migration mechanism is presented and validated against in vivo data. Due to the unique feature of ongoing lateral inhibition, 'stabilised' tip/stalk cell patterns show sensitivity to the formation of new cell-cell junctions during fusion: we predict cell fates can reverse. The fusing tip cells become inhibited and neighbouring stalk cells flip fate, recursively providing new tip cells. Junction size emerges as a key factor in establishing a stable tip/stalk pattern. Cell-cell junctions elongate as tip cells migrate, which is shown to provide positive feedback to lateral inhibition, causing it to be more susceptible to pathological oscillations. Importantly, down-regulation of the migratory pathway alone is shown to be sufficient to rescue the sprouting system from oscillation and restore stability. Thus we suggest the use of migration inhibitors as therapeutic agents for vascular

  3. Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.

    Science.gov (United States)

    Bentley, Katie; Mariggi, Giovanni; Gerhardt, Holger; Bates, Paul A

    2009-10-01

    Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF). Tip cells meet and fuse (anastomosis) to form blood-flow supporting loops. Tip cell selection is achieved by Dll4-Notch mediated lateral inhibition resulting, under normal conditions, in an interleaved arrangement of tip and non-migrating stalk cells. Previously, we showed that the increased VEGF levels found in many diseases can cause the delayed negative feedback of lateral inhibition to produce abnormal oscillations of tip/stalk cell fates. Here we describe the development and implementation of a novel physics-based hierarchical agent model, tightly coupled to in vivo data, to explore the system dynamics as perpetual lateral inhibition combines with tip cell migration and fusion. We explore the tipping point between normal and abnormal sprouting as VEGF increases. A novel filopodia-adhesion driven migration mechanism is presented and validated against in vivo data. Due to the unique feature of ongoing lateral inhibition, 'stabilised' tip/stalk cell patterns show sensitivity to the formation of new cell-cell junctions during fusion: we predict cell fates can reverse. The fusing tip cells become inhibited and neighbouring stalk cells flip fate, recursively providing new tip cells. Junction size emerges as a key factor in establishing a stable tip/stalk pattern. Cell-cell junctions elongate as tip cells migrate, which is shown to provide positive feedback to lateral inhibition, causing it to be more susceptible to pathological oscillations. Importantly, down-regulation of the migratory pathway alone is shown to be sufficient to rescue the sprouting system from oscillation and restore stability. Thus we suggest the use of migration inhibitors as therapeutic agents for vascular normalisation in cancer.

  4. The tipping point: a mathematical model for the profit-driven abandonment of restaurant tipping

    OpenAIRE

    Clifton, Sara M.; Herbers, Eileen; Chen, Jack; Abrams, Daniel M.

    2017-01-01

    The custom of voluntarily tipping for services rendered has gone in and out of fashion in America since its introduction in the 19th century. Restaurant owners that ban tipping in their establishments often claim that social justice drives their decisions, but we show that rational profit-maximization may also justify the decisions. Here, we propose a conceptual model of restaurant competition for staff and customers, and we show that there exists a critical conventional tip rate at which res...

  5. Mental models

    Directory of Open Access Journals (Sweden)

    Marco Antonio Moreira

    1996-12-01

    Full Text Available The mental models subject is presented particularly in the light of Johnson-Laird’s theory. Views from different authors are also presented but the emphasis lies in Johson-Laird’s approach, proposing mental models as a third path in the images x propositions debate. In this perspective, the nature, content, and typology of mental models are discussed, as well as the issue of conciousness and computability. In addition, the methodology of research studies are provided. Essentially, the aim of the paper is to provide an introduction to the mental models topic, having science education research in mind.

  6. Does Intelligence Provide Survival Value?

    OpenAIRE

    Cairns, John

    2009-01-01

    Intelligence is defined as a general mental capacity to reason, plan, solve problems, think abstractly, comprehend ideas, and learn. Intelligence can also be defined as the ability to acquire and apply information gathered from the environment to modify its behavior. It is this intelligence that has allowed the genus Homo to survive for 2 million years. However, recently the global financial meltdown and the deleterious effects of climate change raise the question of whether intelligence has ...

  7. Emergency TIPS in a Child-Pugh B patient: When does the window of opportunity open and close?

    Science.gov (United States)

    Trebicka, Jonel

    2017-02-01

    Transjugular intrahepatic portosystemic shunt (TIPS) is used to treat complications of cirrhosis such as variceal bleeding and refractory ascites, but it also bears the risk of liver failure, overt hepatic encephalopathy (HE) and cardiac decompensation. Variceal bleeding may be controlled using endoscopic and medical treatment in patients with compensated cirrhosis; in decompensated patients, however, TIPS improves survival. Therefore, an early TIPS (within 72h or if later, still early after bleeding) might improve the survival of patients by preventing an inflammatory response and bacterial translocation. Both these processes mediate an impaired immunological and hemodynamic response, thereby facilitating the development of acute-on-chronic liver failure (ACLF) and/or death. Similarly, in patients with refractory ascites, TIPS should be used early in treatment to prevent acute kidney injury (AKI) and hepatorenal syndrome (HRS) after precipitating events induced by complications of portal hypertension. Whether TIPS and/or embolization should be used to treat portal vein thrombosis and spontaneous shunts is still a matter of debate and should be further investigated. In summary, the careful selection of patients for TIPS is crucial. New biomarkers, especially those evaluating systemic inflammation and bacterial translocation, might improve the predictive value of established clinical parameters such as bilirubin and overt HE. However, a significant amount of further research must be carried out. Copyright © 2016 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  8. Cryopreservation of shoot tips of Picrorhiza kurroa Royle ex Benth, an indigenous endangered medicinal plant, through vitrification.

    Science.gov (United States)

    Sharma, Neelam; Sharma, Bindu

    2003-01-01

    The cryopreservation of shoot tips of Picrorhiza kurroa Royle ex Benth (IC 266698), an endangered medicinal plant of India was investigated. Shoot tips (about 1 mm in length) excised from four-week-old proliferating shoot cultures were precultured on MS medium supplemented with various osmotica before dehydrating with PVS2 solution at 0 degrees C. The dehydrated shoot tips were directly immersed in LN2. Following cryopreservation, and after rapid rewarming at 45 degrees C, shoot tips were quickly washed with 1.2 M sucrose solution and then plated on solidified shoot culture medium. Shoot tips were successfully cryopreserved by vitrification, when they were precultured on medium supplemented with 5% DMSO at 4 degrees C for two days before dehydrating in PVS2 for 10-20 minutes at 0 degrees C. Average survival in terms of normal shoot formation after 4 wks of plating was about 20% without callus formation. Cold hardening of shoot cultures for four weeks at 4 degrees C significantly improved the survival and shoot regeneration of cryopreserved shoot tips to 70% and 35%, respectively.

  9. The origins of a wind turbine tip vortex

    NARCIS (Netherlands)

    Micallef, D.; Akay, B.; Simao Ferreira, C.J.; Sant, T.; Van Bussel, G.J.W.

    2014-01-01

    The tip vortex of a wind turbine rotor blade originates as a result of a complex distribution of vorticity along the blade tip thickness. While the tip vortex evolution was extensively studied previously in other work, the mechanism of the initiation of the tip vorticity in a 3D rotating environment

  10. Validation of Tip Corrections for Wind Turbine computations

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Mikkelsen, Robert; Sørensen, Jens Nørkær

    2003-01-01

    Tip loss effect of rotors plays an important role in predictions of wind turbine performance. Classical tip corrections, based on the Prandtl tip reduction function, including Glauert´, Wilson & Lissaman´s and De Vries´ corrections are considered in the paper. In the proximity of the tip...

  11. Doing Mental?

    Science.gov (United States)

    Hobbs, Sandy; And Others

    1980-01-01

    "Mental work" recorded in primary mathematics classes as part of the Classroom Interaction Process is not a simple, single activity of drill or quiz but a set of overlapping activities with different functions. A more analytical approach to mental work is advocated to enhance its usefulness as a classroom activity. (Author/SJL)

  12. Cryopreservation of Thymus cariensis and T. vulgaris shoot tips: comparison of three vitrification-based methods.

    Science.gov (United States)

    Ozudogru, E A; Kaya, E

    2012-01-01

    Thymus is an important genus of the Lamiaceae family, comprising more than 400 perennial aromatic thyme species, which are used extensively for medicinal and culinary purposes. The present study focused on the development of cryopreservation procedures for Thymus vulgaris and T. cariensis, the latter being an endemic and endangered species of Turkey. For cryopreservation of T. vulgaris shoot tips, PVS2-based one-step freezing methods, i.e., PVS2 vitrification, encapsulation-vitrification and droplet-vitrification, were compared. Cold hardening and sucrose preculture were also optimized before the cryopreservation trials. For T. cariensis, a droplet-vitrification method was applied to cold-hardened shoot tips, and after sucrose preculture. In all the methods tested, PVS2 was applied for up to 120 min. The best T. vulgaris cryopreservation was achieved with a droplet-vitrification method, that involved 2-weeks cold hardening of shoot cultures, 48 h preculture of shoot tips on MS medium supplemented with 0.25 M sucrose, and a 90 min PVS2 treatment in droplets. After direct immersion in LN, thawing and plating, 80% of shoot-tips recovered. Post-thaw recovery was significantly lower when the same procedure was applied to T. cariensis shoot tips; however also here 90 min PVS2 treatment produced the highest survival (25 percent) and recovery (25 percent) levels.

  13. Understanding the Plasmonics of Nanostructured Atomic Force Microscopy Tips

    CERN Document Server

    Sanders, Alan; Zhang, Liwu; Turek, Vladimir; Sigle, Daniel O; Lombardi, Anna; Weller, Lee; Baumberg, Jeremy J

    2016-01-01

    Structured metallic tips are increasingly important for optical spectroscopies such as tip-enhanced Raman spectroscopy (TERS), with plasmonic resonances frequently cited as a mechanism for electric field enhancement. We probe the local optical response of sharp and spherical-tipped atomic force microscopy (AFM) tips using a scanning hyperspectral imaging technique to identify plasmonic behaviour. Localised surface plasmon resonances which radiatively couple with far-field light are found only for spherical AFM tips, with little response for sharp AFM tips, in agreement with numerical simulations of the near-field response. The precise tip geometry is thus crucial for plasmon-enhanced spectroscopies, and the typical sharp cones are not preferred.

  14. Endovascular treatment of basilar tip aneurysms associated with moyamoya disease

    Energy Technology Data Exchange (ETDEWEB)

    Arita, K.; Kurisu, K.; Ohba, S.; Shibukawa, M.; Kiura, H.; Sakamoto, S. [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, 734-8551, Hiroshima (Japan); Uozumi, T. [Hibino Hospital, Hiroshima (Japan); Nakahara, T. [Division of Neuroendovascular Treatment, Mazda Hospital, Hiroshima (Japan)

    2003-07-01

    We report the efficacy and safety of endovascular treatment of basilar tip aneurysms (BTA) in five patients with moyamoya disease. The patients underwent intra-aneurysmal embolisation with detachable platinum coils. Three BTA presented with subarachnoid haemorrhage (SAH); the other two were asymptomatic. In four cases, one embolisation procedure produced >95% angiographic obliteration of the aneurysm. In the other patient, 80-90% obliteration was achieved initially, but due to growth of the residual aneurysm, the procedure was repeated 7 months later. Two patients experienced transient oculomotor paresis as a procedure-related complication. Mean follow-up was 43.6{+-}34.0 months (range 8-92 months). One patient died of putaminal haemorrhage unrelated to the aneurysm 15 months after embolisation. The other four had no subsequent SAH and survived without sequelae. Endovascular embolisation using detachable platinum coils proved to be a safe and efficient treatment modality for BTA associated with moyamoya disease. (orig.)

  15. Innovations’ Survival

    Directory of Open Access Journals (Sweden)

    Jakub Tabas

    2016-01-01

    Full Text Available Innovations currently represent a tool of maintaining the going concern of a business entity and its competitiveness. However, effects of innovations are not infinite and if an innovation should constantly preserve a life of business entity, it has to be a continual chain of innovations, i.e. continual process. Effective live of a single innovation is limited while the limitation is derived especially from industry. The paper provides the results of research on innovations effects in the financial performance of small and medium-sized enterprises in the Czech Republic. Objective of this paper is to determine the length and intensity of the effects of technical innovations in company’s financial performance. The economic effect of innovations has been measured at application of company’s gross production power while the Deviation Analysis has been applied for three years’ time series. Subsequently the Survival Analysis has been applied. The analyses are elaborated for three statistical samples of SMEs constructed in accordance to the industry. The results obtained show significant differences in innovations’ survival within these three samples of enterprises then. The results are quite specific for the industries, and are confronted and discussed with the results of authors’ former research on the issue.

  16. 26 CFR 31.3401(f)-1 - Tips.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Tips. 31.3401(f)-1 Section 31.3401(f)-1... Income Tax at Source § 31.3401(f)-1 Tips. (a) Tips considered wages. Tips received after 1965 by an... income tax at source. For an exception to the rule that tips constitute wages, see §§ 31.3401(a)(16) and...

  17. 26 CFR 31.3121(a)(12)-1 - Tips.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Tips. 31.3121(a)(12)-1 Section 31.3121(a)(12)-1... Contributions Act (Chapter 21, Internal Revenue Code of 1954) General Provisions § 31.3121(a)(12)-1 Tips. The... tips if— (a) The tips are paid in any medium other than cash, or (b) The cash tips received by an...

  18. 78 FR 13402 - Proposed Collection; Comment Request for Tip Reporting Alternative Tip Agreement Used in the...

    Science.gov (United States)

    2013-02-27

    ... Used in the Cosmetology and Barber Industry AGENCY: Internal Revenue Service (IRS), Treasury. ACTION..., the IRS is soliciting comments concerning tip reporting alternative commitment used in the cosmetology...: Tip Reporting Alternative Commitment Agreement used in the Cosmetology and Barber Industry. OMB Number...

  19. 75 FR 11226 - Proposed Collection; Comment Request for Tip Reporting Alternative Tip Agreement Used in the...

    Science.gov (United States)

    2010-03-10

    ... Used in the Cosmetology and Barber Industry AGENCY: Internal Revenue Service (IRS), Treasury. ACTION..., the IRS is soliciting comments concerning Tip Reporting Alternative Commitment used in the Cosmetology...: Tip Reporting Alternative Commitment Agreement used in the Cosmetology and Barber Industry. OMB Number...

  20. The genocidal mentality

    Energy Technology Data Exchange (ETDEWEB)

    Lifton, R.J.; Markusen, E.

    1990-01-01

    Since the dropping of the atomic bombs on Hiroshima and Nagasaki, the world has witnessed the insidious growth of a genocidal system-a constellation of men, weapons, and war-fighting plans which, if implemented, could put an end to life on this planet. In this book, the cast of mind that created and maintains this threat is examined and an alternative, more hopeful direction is suggested. This book draws on the lessons of the Holocaust- and presents a picture of the genocidal mentality. If we are to survive this genocidal mentality must give way to a species self, to a deepened awareness of belonging to a single species. This shift in mind-set would enable us to renounce nuclearism and to envision a genuine human future.

  1. Evaluation of crack tip constraint using photoelasticity

    Energy Technology Data Exchange (ETDEWEB)

    Ayatollahi, M.R.; Safari, H

    2003-09-01

    The method of photoelasticity has been used extensively in the past for investigating elastic stresses in cracked specimens. However, previous studies concentrate predominantly on different methods for determining the stress intensity factors. Some of these methods make use of the higher order stress terms including the T-stress to achieve more accurate experimental results for stress intensity factors. Nevertheless, the effect of T-stress on the stress fields near the crack tip has received little attention in previous photoelastic studies. In this paper, a two-parameter formulation is used to study how the T-stress influences the isochromatic fringe patterns around the tip of a mode I crack. Theoretical and experimental results obtained in this research show that the isochromatic fringes near the crack tip rotate forward and backward for negative and positive values of T-stress, respectively. Therefore, the experimental technique of photoelasticity can be used to distinguish low constraint cracked components from high constraint ones.

  2. Tip vortices in the actuator line model

    Science.gov (United States)

    Martinez, Luis; Meneveau, Charles

    2017-11-01

    The actuator line model (ALM) is a widely used tool to represent the wind turbine blades in computational fluid dynamics without the need to resolve the full geometry of the blades. The ALM can be optimized to represent the `correct' aerodynamics of the blades by choosing an appropriate smearing length scale ɛ. This appropriate length scale creates a tip vortex which induces a downwash near the tip of the blade. A theoretical frame-work is used to establish a solution to the induced velocity created by a tip vortex as a function of the smearing length scale ɛ. A correction is presented which allows the use of a non-optimal smearing length scale but still provides the downwash which would be induced using the optimal length scale. Thanks to the National Science Foundation (NSF) who provided financial support for this research via Grants IGERT 0801471, IIA-1243482 (the WINDINSPIRE project) and ECCS-1230788.

  3. Tipping elements in the Arctic marine ecosystem.

    Science.gov (United States)

    Duarte, Carlos M; Agustí, Susana; Wassmann, Paul; Arrieta, Jesús M; Alcaraz, Miquel; Coello, Alexandra; Marbà, Núria; Hendriks, Iris E; Holding, Johnna; García-Zarandona, Iñigo; Kritzberg, Emma; Vaqué, Dolors

    2012-02-01

    The Arctic marine ecosystem contains multiple elements that present alternative states. The most obvious of which is an Arctic Ocean largely covered by an ice sheet in summer versus one largely devoid of such cover. Ecosystems under pressure typically shift between such alternative states in an abrupt, rather than smooth manner, with the level of forcing required for shifting this status termed threshold or tipping point. Loss of Arctic ice due to anthropogenic climate change is accelerating, with the extent of Arctic sea ice displaying increased variance at present, a leading indicator of the proximity of a possible tipping point. Reduced ice extent is expected, in turn, to trigger a number of additional tipping elements, physical, chemical, and biological, in motion, with potentially large impacts on the Arctic marine ecosystem.

  4. Magnetic vortices induced by a moving tip

    Science.gov (United States)

    Magiera, Martin P.; Hucht, Alfred; Wolf, Dietrich E.

    2013-03-01

    A two-dimensional easy-plane ferromagnetic substrate interacting with a dipolar tip which is magnetized perpendicular with respect to the easy plane is studied numerically by solving the Landau-Lifshitz Gilbert equation [Europhys. Lett. 100, 27004 (2012)]. Due to the symmetry of the dipolar field of the tip, in addition to the collinear structure a magnetic vortex structure becomes stable. It is robust against excitations caused by the motion of the tip. The moved vortex structure shows an increased energy dissipation compared to the collinear structure. We show that for high excitations the system may perform a transition between the two states. The influence of domain walls, which may also induce this transition, is examined. Financial support by the German Research Foundation (DFG) through SFB 616 ``Energy Dissipation at Surfaces'' and the German Exchange Association (DAAD) through the Project Related Exchange Brazil-Germany (PROBRAL) is acknowledged.

  5. What Is Mental Health?

    Science.gov (United States)

    ... Myths and Facts Recovery Is Possible What Is Mental Health? Mental health includes our emotional, psychological, and social ... mental health problems and where to find help . Mental Health and Wellness Positive mental health allows people to: ...

  6. Twelve tips for supervising research students.

    Science.gov (United States)

    Siddiqui, Zarrin Seema; Jonas-Dwyer, Diana R D

    2012-01-01

    Research supervision is a task that requires a set of abilities and skills. Many academics begin research supervision as novices and develop their abilities and skills through experience over time. We aim to provide advice about research supervision to prospective supervisors. We used critical reflection of our experiences, including feedback received from students under supervision as well as advice from the literature to develop these tips. Twelve tips are presented to assist faculty with research supervision. Research supervision is an important component of many medical academics' work. Beginning supervisors need to understand the dynamics and practicalities of supervision before they embark on this process.

  7. Social tipping points and Earth systems dynamics

    Directory of Open Access Journals (Sweden)

    R. Alexander eBentley

    2014-08-01

    Full Text Available Recently, Early Warning Signals (EWS have been developed to predict tipping points in Earth Systems. This discussion highlights the potential to apply EWS to human social and economic systems, which may also undergo similar critical transitions. Social tipping points are particularly difficult to predict, however, and the current formulation of EWS, based on a physical system analogy, may be insufficient. As an alternative set of EWS for social systems, we join with other authors encouraging a focus on heterogeneity, connectivity through social networks and individual thresholds to change.

  8. Tipping points in the dynamics of speciation.

    Science.gov (United States)

    Nosil, Patrik; Feder, Jeffrey L; Flaxman, Samuel M; Gompert, Zachariah

    2017-01-24

    Speciation can be gradual or sudden and involve few or many genetic changes. Inferring the processes generating such patterns is difficult, and may require consideration of emergent and non-linear properties of speciation, such as when small changes at tipping points have large effects on differentiation. Tipping points involve positive feedback and indirect selection stemming from associations between genomic regions, bi-stability due to effects of initial conditions and evolutionary history, and dependence on modularity of system components. These features are associated with sudden 'regime shifts' in other cellular, ecological, and societal systems. Thus, tools used to understand other complex systems could be fruitfully applied in speciation research.

  9. Tip-Based Nanofabrication for Scalable Manufacturing

    Directory of Open Access Journals (Sweden)

    Huan Hu

    2017-03-01

    Full Text Available Tip-based nanofabrication (TBN is a family of emerging nanofabrication techniques that use a nanometer scale tip to fabricate nanostructures. In this review, we first introduce the history of the TBN and the technology development. We then briefly review various TBN techniques that use different physical or chemical mechanisms to fabricate features and discuss some of the state-of-the-art techniques. Subsequently, we focus on those TBN methods that have demonstrated potential to scale up the manufacturing throughput. Finally, we discuss several research directions that are essential for making TBN a scalable nano-manufacturing technology.

  10. Windows 7 Annoyances Tips, Secrets, and Solutions

    CERN Document Server

    Karp, David

    2010-01-01

    Windows 7 may be faster and more stable than Vista, but it's a far cry from problem-free. David A. Karp comes to the rescue with the latest in his popular Windows Annoyances series. This thorough guide gives you the tools you need to fix the troublesome parts of this operating system, plus the solutions, hacks, and timesaving tips to make the most of your PC. Streamline Windows Explorer, improve the Search tool, eliminate the Green Ribbon of Death, and tame User Account Control promptsExplore powerful Registry tips and tools, and use them to customize every aspect of Windows and solve its sho

  11. Study of tip loss corrections using CFD rotor computations

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Zhu, Wei Jun; Sørensen, Jens Nørkær

    2014-01-01

    computations for wind turbines with sharp tip. Using the technique of determination of angle of attack and the CFD results for a NordTank 500 kW rotor, airfoil data are extracted and a new tip loss function on airfoil data is derived. To validate, BEM computations with the new tip loss function are carried out...... and compared with CFD results for the NordTank 500 kW turbine and the NREL 5 MW turbine. Comparisons show that BEM with the new tip loss function can predict correctly the loading near the blade tip.......Tip loss correction is known to play an important role for engineering prediction of wind turbine performance. There are two different types of tip loss corrections: tip corrections on momentum theory and tip corrections on airfoil data. In this paper, we study the latter using detailed CFD...

  12. Turbine blade squealer tip rail with fence members

    Science.gov (United States)

    Little, David A

    2012-11-20

    A turbine blade includes an airfoil, a blade tip section, a squealer tip rail, and a plurality of chordally spaced fence members. The blade tip section includes a blade tip floor located at an end of the airfoil distal from the root. The blade tip floor includes a pressure side and a suction side joined together at chordally spaced apart leading and trailing edges of the airfoil. The squealer tip rail extends radially outwardly from the blade tip floor adjacent to the suction side and extends from a first location adjacent to the airfoil trailing edge to a second location adjacent to the airfoil leading edge. The fence members are located between the airfoil leading and trailing edges and extend radially outwardly from the blade tip floor and axially from the squealer tip rail toward the pressure side.

  13. Dielectrophoretic positioning of single nanoparticles on atomic force microscope tips for tip-enhanced Raman spectroscopy.

    Science.gov (United States)

    Leiterer, Christian; Deckert-Gaudig, Tanja; Singh, Prabha; Wirth, Janina; Deckert, Volker; Fritzsche, Wolfgang

    2015-05-01

    Tip-enhanced Raman spectroscopy, a combination of Raman spectroscopy and scanning probe microscopy, is a powerful technique to detect the vibrational fingerprint of molecules at the nanometer scale. A metal nanoparticle at the apex of an atomic force microscope tip leads to a large enhancement of the electromagnetic field when illuminated with an appropriate wavelength, resulting in an increased Raman signal. A controlled positioning of individual nanoparticles at the tip would improve the reproducibility of the probes and is quite demanding due to usually serial and labor-intensive approaches. In contrast to commonly used submicron manipulation techniques, dielectrophoresis allows a parallel and scalable production, and provides a novel approach toward reproducible and at the same time affordable tip-enhanced Raman spectroscopy tips. We demonstrate the successful positioning of an individual plasmonic nanoparticle on a commercial atomic force microscope tip by dielectrophoresis followed by experimental proof of the Raman signal enhancing capabilities of such tips. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Families with Special Needs: Caregiving Tips

    Science.gov (United States)

    ... Diabetes and Children Epilepsy HIV/AIDS Intimate Partner Violence Lead Poisoning Mental Health Pregnancy and Reproductive Health Smoking and Tobacco Traumatic Brain Injury PEARLS Gives Seniors ...

  15. Barbecue Basics: Tips to Prevent Foodborne Illness

    Medline Plus

    Full Text Available ... For Consumers Home For Consumers Consumer Updates Barbecue Basics: Tips to Prevent Foodborne Illness Share Tweet Linkedin ... and 140°F, so summer heat makes the basics of food safety especially important. “Fortunately, there are ...

  16. What Do You Mean, 'Tipping Point'?

    NARCIS (Netherlands)

    Nes, van E.H.; Shojaei Arani, M.; Staal, A.; Bolt, van der B.; Flores, Bernardo M.; Bathiany, S.; Scheffer, M.

    2016-01-01

    Over the past 10 years the use of the term ‘tipping point’ in the scientific literature has exploded. It was originally used loosely as a metaphor for the phenomenon that, beyond a certain threshold, runaway change propels a system to a new state. Although several specific mathematical definitions

  17. Tips: Improving Acoustics for Music Teaching.

    Science.gov (United States)

    Geerdes, Harold P.

    A specifications pamphlet offers methods, ideas, and suggestions on how music educators can upgrade their existing music facilities or design new ones correctly. Guidelines address room acoustic fundamentals, how to critique a music room, hints on upgrading acoustic weaknesses, and general tips to follow when trying to maximize acoustics when…

  18. Microtubules guide root hair tip growth

    NARCIS (Netherlands)

    Sieberer, B.; Ketelaar, M.J.; Esseling, J.J.; Emons, A.M.C.

    2005-01-01

    The ability to establish cell polarity is crucial to form and function of an individual cell. Polarity underlies critical processes during cell development, such as cell growth, cell division, cell differentiation and cell signalling. Interphase cytoplasmic microtubules in tip-growing fission yeast

  19. Social Media Tips to Enhance Medical Education.

    Science.gov (United States)

    Shah, Vikas; Kotsenas, Amy L

    2017-06-01

    In this article, we describe how social media can supplement traditional education, articulate the advantages and disadvantages of various social media platforms for both teachers and learners, discuss best practices to maintain confidentiality of protected health information, and provide tips for implementing social media-based teaching into the training curriculum. Copyright © 2017 The Association of University Radiologists. All rights reserved.

  20. Technology Tips and Tricks for Music Educators

    Science.gov (United States)

    Peterson, Hal

    2006-01-01

    This article presents technology tips and ideas for music educators. To keep current with music technology, you will need to spend time with it regularly, just like you would practice a musical instrument or voice. Basic office software programs can help you with administrative tasks and duties. Your computers are important tools for your program,…

  1. Adipogenesis: forces that tip the scales

    DEFF Research Database (Denmark)

    MacDougald, Ormond A; Mandrup, Susanne

    2001-01-01

    factors reviewed include Wnt, transforming growth factor beta, inflammatory cytokines and prostaglandin F(2alpha). Tipping the scales towards or away from adipogenesis has profound implications for human health. In this review, we describe recent contributions to the field and will focus on factors...

  2. Phase transformation in AFM silicon tips

    Science.gov (United States)

    Kopycinska-Müller, M.; Barth, M.; Küttner, M.; Köhler, B.

    2017-09-01

    We confirmed the occurrence of phase transformations in an atomic force microscopy silicon tip during loading and unloading experiments performed on a polycrystalline Ti sample. The influence of the phase transformations on the effective mechanical and electrical properties of the tip was observed with the help of load-unload curves measured simultaneously for the tip-sample contact stiffness k * and the effective electrical resistance of the system R eff. We used the atomic force acoustic microscopy (AFAM) method to determine the values of k *. To measure the changes in R eff, we combined a high voltage source/measure unit with the existing AFAM system. The data obtained showed that the phase transformation from Si-I to Si-II is preceded by other structural changes such as formation of distorted diamond structures and formation of Si-III. This conclusion was reached after observing a small hysteretic behavior in the load-unload stiffness curve accompanied by only very small changes in the resistance of the tip-sample system occurring on the unloading. The coinciding of a sudden increase in the values of the contact stiffness with a decrease in the resistance of the system indicated that the formation of metallic Si-II occurred in the subsequent measurements. The interpretation of our results found confirmation in the results of molecular dynamics and atomistic simulations performed for silicon under nanoindentation experiments.

  3. Video Tips for Worry-Free Presentations

    Science.gov (United States)

    Berendsen, M.; Santascoy, J.

    2011-09-01

    Amateur astronomers and other volunteer informal science educators express concerns when talking with the public since they often lack specific training in public speaking. The Astronomical Society of the Pacific has developed a series of videos and supporting materials to provide tips and exercises for practicing the skills associated with the most commonly expressed concerns.

  4. Nanobits - exchangable and customisable scanning probe tips

    DEFF Research Database (Denmark)

    Yildiz, Izzet

    Invention of atomic force microscopy (AFM) pioneered a novel aspect for the surface metrology concept. A range of scanning probe methods have been developed over the years based on different sorts of tip-surface interaction: electrical, optical, thermal, force. Reproducible and fast fabrication...

  5. Fast Food: Tips for Choosing Healthier Options

    Science.gov (United States)

    ... what you order. Consider these tips. If the fast-food restaurant offers several sandwich sizes, pick the smallest. Bypass hamburgers with two or three beef patties, which can be close to 800 calories. Choose instead a regular- or children's-sized hamburger, which has about 250 calories. And ...

  6. Tip cells: master regulators of tubulogenesis?

    Science.gov (United States)

    Weavers, Helen; Skaer, Helen

    2014-07-01

    The normal development of an organ depends on the coordinated regulation of multiple cell activities. Focusing on tubulogenesis, we review the role of specialised cells or groups of cells that are selected from within tissue primordia and differentiate at the outgrowing tips or leading edge of developing tubules. Tip or leading cells develop distinctive patterns of gene expression that enable them to act both as sensors and transmitters of intercellular signalling. This enables them to explore the environment, respond to both tissue intrinsic signals and extrinsic cues from surrounding tissues and to regulate the behaviour of their neighbours, including the setting of cell fate, patterning cell division, inducing polarity and promoting cell movement and cell rearrangements by neighbour exchange. Tip cells are also able to transmit mechanical tension to promote tissue remodelling and, by interacting with the extracellular matrix, they can dictate migratory pathways and organ shape. Where separate tubular structures fuse to form networks, as in the airways of insects or the vascular system of vertebrates, specialised fusion tip cells act to interconnect disparate elements of the developing network. Finally, we consider their importance in the maturation of mature physiological function and in the development of disease. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  7. Tip-enhanced bulk photovoltaic effect

    Science.gov (United States)

    Sturman, B.; Podivilov, E.

    2017-10-01

    Using the conventional macroscopic description of the bulk photovoltaic effect we analyze the light-induced currents and electric fields arising in the optical configuration with a continuous bottom electrode and a small circular top electrode. This scheme is relevant to recent experiments on the tip-enhanced photovoltaic effect in ferroelectrics. It is shown that a light-induced electric field remains nonzero inside the sample even in the short-circuit regime. Moreover, it is enhanced compared to the photovoltaic field in a large area and strongly enhanced near the top electrode. A field-assisted collection of charge carriers from the illuminated area produces a strong local enhancement of the current density near the top electrode. The tip-enhanced electric field is typically parallel to the photovoltaic current. It is sufficient to repolarize the crystal near the top electrode. The effect of the tip enhancement on the light-current transformation efficiency is considered, and predictions for the tip radius and sample thickness dependencies of the total light-induced current are made.

  8. Tips for Older Dietary Supplement Users

    Science.gov (United States)

    ... Administration, DHHS, Center for Food Safety and Applied Nutrition: Dietary Supplements Tips for the Savvy Supplement User: Making Informed ... that supplements include botanical/herbal as well as vitamin/mineral ... may see sold as dietary supplements. It is not possible to list them all ...

  9. Tips for Building a Classroom Library.

    Science.gov (United States)

    Schleper, David R.

    1991-01-01

    Eleven tips to teachers of hearing-impaired students wanting to build a classroom library include seeking community donations; joining book clubs; borrowing from the school library; involving the parent/teacher association; calling on the deaf community; contacting local service organizations; and asking for discounts. (DB)

  10. Tips for Healthy Children and Families

    Science.gov (United States)

    ... will help you make smart choices for your family. Children imitate their parents, so it’s important to set a good example. The tips below can help your family be healthy and happy.Path to improved healthEating better (for children and families)Start the day with a healthy ...

  11. Have Diabetes? Get Tips for Safe Travels

    Science.gov (United States)

    ... this? Submit Button Past Emails Have Diabetes? Get Tips for Safe Travels Language: English (US) Español (Spanish) ... file Microsoft PowerPoint file Microsoft Word file Microsoft Excel file Audio/Video file Apple Quicktime file RealPlayer ...

  12. Barbecue Basics: Tips to Prevent Foodborne Illness

    Medline Plus

    Full Text Available ... Español Search FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, ... Biologics Animal & Veterinary Cosmetics Tobacco Products For Consumers Home For Consumers Consumer Updates Barbecue Basics: Tips to ...

  13. A refined tip correction based on decambering

    DEFF Research Database (Denmark)

    Sørensen, Jens Nørkær; Dag, Kaya Onur; Ramos García, Néstor

    2016-01-01

    A new tip correction for use in performance codes based on the blade element momentum (BEM) or the lifting-line techniqueis presented. The correction modifies the circulation by taking into account the additional influence of the inductionof the vortices in the wake, using the so-called decamberi...

  14. Take a Tip from the Cubs

    Science.gov (United States)

    Fornaciari, James

    2016-01-01

    As legendary Cubs manager Joe Maddon did with his players, seeing students as people first works for teachers who hope to build cohesive classes that achieve. Maddon's strength was his emphasis on cultivating positive relationships among his players. Taking a tip from Maddon's strategy, Fornaciari, an Advanced Placement history teacher, shares…

  15. Barbecue Basics: Tips to Prevent Foodborne Illness

    Medline Plus

    Full Text Available ... health and wellness tips, and the latest safety info on FDA-regulated products and public health issues. ... Hampshire Avenue Silver Spring, MD 20993 1-888-INFO-FDA (1-888-463-6332) Contact FDA Subscribe ...

  16. Copyright Tips for Editors and Publishers.

    Science.gov (United States)

    Polansky, Barbara Friedman

    1985-01-01

    Expands on three main copyright tips as they apply to editors and publishers: (1) know copyright basics (copyright notice, copyright registration, fair use); (2) know whom to contact if you have copyright questions or if you need to obtain copyright permission; and (3) communicate questions, intentions, and policies clearly and fully. (EJS)

  17. Tips to Making Successful School Board Presentations

    Science.gov (United States)

    Cheasty, Michelle

    2011-01-01

    Over the years, the author has had the opportunity to make several presentations to school boards. The author offers some tips and tricks she has learned, having given board presentations about the specific topics she listed in this article, and receiving feedback after each presentation. She points out that the most important thing to keep in…

  18. Tips for Teaching Textiles and Clothing.

    Science.gov (United States)

    New York State Education Dept., Albany. Bureau of Continuing Education Curriculum Development.

    This guide was prepared to help instructors of adult textiles and clothing programs improve their teaching; it is designed to be used with other department publications: Clothing Services Training Guide, Resource Courses for Planning Local Adult Homemaking Programs, and Resource Kit Tips for Teaching Textiles and Clothing (see AC 008 741). Each…

  19. Final Technical Report: Electrohydrodynamic Tip Streaming

    Energy Technology Data Exchange (ETDEWEB)

    Basaran, Osman [Purdue Univ., West Lafayette, IN (United States)

    2016-01-06

    When subjected to strong electric fields, liquid drops and films form conical tips and emit thin jets from their tips. Such electrodydrodynamic (EDH) tip streaming or cone-jetting phenomena, which are sometimes referred to as electrospraying, occur widely in nature, e.g., in ejection of streams of small charged drops from pointed tips of raindrops in thunderclouds, and technology, e.g., in electrospray mass spectrometry or electric field-driven solvent extraction. More recently, EHD cone-jetting has emerged as a powerful technique for direct printing of solar cells, micro- and nano- particle production, and microencapsulation for controlled release. In many of the aforementioned situations, of equal importance to the processes by which one drop disintegrates to form several drops are those by which (a) two drops come together and coalesce and (b) two drops are coupled to form a double droplet system (DDS) or a capillary switch (CS). the main objective of this research program is to advance through simulation, theory, and experiment the breakup, coalescence, and oscillatory dynamics of single and pairs of charged as well as uncharged drops.

  20. Combined therapy of transjuglar intrahepatic portosystemic shunt (TIPS) and transcatheter hepatic artery chemoembolization (TACE) in patients with hepatocellular carcinoma and gastroesophageal variceal bleedings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yong Joo; Kim, Byung Ki; Ryeom, Hun Kyu; Lee, Jong Min; Kang, Duk Sik [Kyungpook National Univ. Hospital, Taegu (Korea, Republic of)

    1998-06-01

    The purpose of this study is to evaluate the efficacy of combined TIPS and superselective TACE therapy in patients with hepatocellular carcinoma and variceal bleedings. Of a total of 132 patients who underwent TIPS, 14 had hepatocellular carcinoma; of these six with a patent main portal vein who had undergone TACE were included this study. One underwent TIPS 13 months after TACE, and five underwent TACE at various points during the TIPS follow-up period. TIPS followed the standard procedure, while TACE involved superselective segmental or subsegmental embolization in four patients, lobar artery embolization in one, and non-selective chemoembolization in one with on advanced tumor. Except for mild hepatic encephalophy in two patients, no clinically significant immediate complication was seen after TIPS or TACE. Three patients died due to hepatic failure; they survived for one to three months after combined therapy, a mean of 2.3 months. After combined therapy, other patients survived for between five and 49 (mean, 22) months. Combined TIPS and TACE therapy is effective for the treatment of patients with hepatocellular carcinoma and esophagogastric variceal bleeding. (author). 13 refs., 1 tab., 3 figs.

  1. Tipping news in information accumulation system

    Science.gov (United States)

    Shin, J. K.

    2010-05-01

    As a continuous opinion dynamics model, the information accumulation system (IAS) includes three basic mechanisms of the news, the inheritance and the diffusion as contributing to the information accumulation process of a system. A system is composed of agents who diffuse information through internal interaction, while each of them has incomplete memory or inheritance rate. The news comes from external sources of information, such as mass media. Previously the model IAS was studied only for the small news problems. In this study, a tipping news problem is considered. A key question of the problem is: what is the minimum strength of advertisement that can tip the minority opinion to a majority one? Dynamics of the IAS is briefly revisited with a special interest on nonlinear behavior of the model. In particular, it is shown that a discrete map of the IAS for a single color problem can be transformed into a logistic map, from which the dynamics of the IAS can be better understood. To show the applicability of the IAS model, the result is applied to explain the concept of the critical population size, which claims that there is a minimum population size for a social knowledge system to be continuously inherited without being lost. And critical size of the tipping news is found analytically in terms of IAS parameters. Some of the key results from the present study are compared in detail with the results from the Brownian particle model, which is believed to be the most similar model to the IAS. The concept of tipping news is used to show that a traditional society can tip at an exceptionally low inter-community exposure. Finally, the result was applied to the language competition problem.

  2. Mental Byomdannelse

    DEFF Research Database (Denmark)

    Olsen, Tina Vestermann; Boye, Anne Mette; Borchmann, Inger Haarup

    Formålet med publikationen er at præsentere metoden "Mental byomdannelse". Metoden viser, hvordan man via midlertidig brug af grunde kan undersøge et steds potentialer, tage et område i brug tidligt i en byomdannelsesproces og derved bidrage til at opbygge en ny identitet for området. Mental...... byomdannelse går ud på at skabe bevidsthed om et byudviklingsområde overfor byens borgere, kommende beboere og fremtidige brugere af området allerede mens den fysiske omdannelse er i gang. I publikationen præsenteres en værktøjskasse, som giver redskaber og ideer til, hvordan man kan sætte en mental...... byomdannelsesproces i gang i byens rum. Publikationen udgør en afrapportering fra et støttet forsøgsprojekt hvor metoden ”Mental byomdannelse” er udviklet ved at afprøve ideerne om mental byomdannelse i to cases i Ålborg Kommune, hhv. i Østre Havn og Nibe by. Formålet med at anvende metoden i de to cases har været...

  3. CRYOPRESERVATION OF SWEET POTATO SHOOT TIPS USING A DROPLET-VITRIFICATION PROCEDURE.

    Science.gov (United States)

    Park, S U; Kim, H H

    2015-01-01

    Sweet potato is a staple food worldwide, but a problematic species in terms of long term storage, as it is not suitable for germplasm conservation. This study aimed to develop cryopreservation protocols for sweet potato shoot tips based on a droplet-vitrification procedure. As a standard procedure, sweet potato shoot tips were precultured in a liquid MS medium supplemented with 10% sucrose (S-10%) and 17.5% sucrose (S-17.5%) for 31 and 17 h, respectively. They were then osmoprotected with C4-35% (17.5% glycerol + 17.5% sucrose) for 50 min and cryoprotected with PVS3 (50% glycerol + 50% sucrose) for 60 min. A set of experiments was designed to investigate critical factors, i.e. stepwise sucrose preculture, osmoprotection, cryoprotection with PVS2- and PVS3-based vitrification solutions, and their combinational effect, as well as temperature alteration through placement in a cooling/rewarming container. Sucrose preculture was determined to be necessary for the adaptation of sweet potato shoot tips to cryoprotection with PVS3, and the highest post-thaw (LN) regeneration rate was observed in a preculture with S-10% for 31 h → S-17.5% for 17 h (19.0%). The effect of one-step or two-step osmoprotection was not significant on survival or regeneration of either the cryoprotected-control (LNC) or LN shoot tips. Responses of sweet potato shoot tips to osmoprotection and cryoprotection were linked to the level of sucrose preculture. The use of alumimium foil strips (droplet-vitrification) resulted in significantly higher LN survival (89.8%) and regeneration (19.0%), compared to those using cryovials (vitrification, 67.2% and 0%, respectively). LN regeneration increased by 67.5% when cryopreserved shoot tips were transferred to a new postculture medium. This study demonstrates that the combination of stepwise sucrose preculture with a higher final concentration (up to 17.5%), cryoprotection with PVS3 and cooling with foil strip is crucial to the regeneration of LN sweet

  4. Menopause: Treatment Tips From the National Institute on Aging

    Science.gov (United States)

    ... Menopause Treatment Tips From the National Institute on Aging Past Issues / Winter 2017 Table of Contents Possible ... Menopause / Treatment Tips From the National Institute on Aging / Menopause Mayhem / Weighing Your Treatment Options Winter 2017 ...

  5. Essential Tremor (ET): Coping Tips for Everyday Living

    Science.gov (United States)

    ... Options Donate Prev Next IETF > Coping with Essential Tremor > Coping Tips for Everyday Living Coping Tips for ... that can lead to stress with temporarily worsening tremor. In order to assist people who have ET ...

  6. Early-warning indicators for rate-induced tipping.

    Science.gov (United States)

    Ritchie, Paul; Sieber, Jan

    2016-09-01

    A dynamical system is said to undergo rate-induced tipping when it fails to track its quasi-equilibrium state due to an above-critical-rate change of system parameters. We study a prototypical model for rate-induced tipping, the saddle-node normal form subject to time-varying equilibrium drift and noise. We find that both most commonly used early-warning indicators, increase in variance and increase in autocorrelation, occur not when the equilibrium drift is fastest but with a delay. We explain this delay by demonstrating that the most likely trajectory for tipping also crosses the tipping threshold with a delay, and therefore, the tipping itself is delayed. We find solutions of the variational problem determining the most likely tipping path using numerical continuation techniques. The result is a systematic study of the most likely tipping time in the plane of two parameters, distance from tipping threshold and noise intensity.

  7. Tips for Good Health in Later Life: For Older Women

    Science.gov (United States)

    ... Geriatrics Osteoporosis Prevention Related Documents PDF Tips for Good Health in Later Life: For Older Women Download Join our e-newsletter! Resources Tips for Good Health in Later Life: For Older Women Tools and ...

  8. Restaurant Dining: Seven Tips for Staying Gluten Free

    Science.gov (United States)

    ... Education Bulletin Restaurant Dining: Seven Tips for Staying Gluten-Free Updated May 2014 Tips for Dining Away ... 1. Selection of eating establishment. • Your success at gluten-free dining will be determined by a number ...

  9. Tips to Help Children through Their Medical Tests

    Science.gov (United States)

    ... Acidosis and Alkalosis Adrenal Insufficiency and Addison Disease Alcoholism Allergies Alzheimer Disease Anemia Angina Ankylosing Spondylitis Anthrax ... Tips on Blood Testing Tips to Help the Elderly through Their Medical Tests Elsewhere On The Web ...

  10. Cytology of root tips of Dioscoreophyllum cumminsii (STAPF) diel ...

    African Journals Online (AJOL)

    , University of Nigeria Nsukka. Root tips for the chromosome work were obtained from three sources: runners originating from main vine; sprouting pieces of tubers and redifferentiated root tips from callus. The results showed that normal ...

  11. Application of Orthodromic Island Flap Prosthetics of Homo-Digital Artery in Finger-Tip Defect

    Directory of Open Access Journals (Sweden)

    Daming Lu

    2014-03-01

    Full Text Available Objective: To investigate the clinical efficacy of orthodromic island flap prosthetics of homodigital artery on finger-tip defect. Methods: A total of 21 patients with finger-tip defect from December, 2010 to April, 2013 were given orthodromic island flap prosthetics of homo-digital artery, with the maximum and minimum sizes of flaps being 20 mm×22 mm and 10 mm×15 mm, respectively. Results: All patients with finger-tip defect survived from the flap surgery and the wounds were favorably healed. 3 - 12 months follow-up after operation, the flaps were observed with approving appearance, soft texture and favorable elasticity, with two-point discrimination being 6 - 8 mm. According to TAM detection of hand functions, flaps were excellent healed in 19 cases, good and fairish in 1 case respectively, with effective rate being 95.2%. Conclusion: Orthodromic island flap prosthetics of homo-digital artery is simple and safe in operation with satisfactory effcacy, being the most ideal method for the repair of finger-tip defect.

  12. 23 CFR 450.330 - Project selection from the TIP.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project selection from the TIP. 450.330 Section 450.330... from the TIP. (a) Once a TIP that meets the requirements of 23 U.S.C. 134(j), 49 U.S.C. 5303(j), and § 450.324 has been developed and approved, the first year of the TIP shall constitute an “agreed to...

  13. 26 CFR 31.3401(a)(16)-1 - Tips.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Tips. 31.3401(a)(16)-1 Section 31.3401(a)(16)-1... Income Tax at Source § 31.3401(a)(16)-1 Tips. Tips paid to an employee are excepted from wages and hence not subject to withholding if— (a) The tips are paid in any medium other than cash, or (b) The cash...

  14. The Effects of Service Quality on Customers’ Tipping Behavior

    OpenAIRE

    Murat Yesiltas; Ozcan Zorlu; Serhat Adem Sop; Elif Tuba Beydilli

    2014-01-01

    In recent years, customer tipping behaviors have become one of the most debated issues in the context of tourist behaviors and social norms. And the numerous studies have begun to focus on searching the main determiners of tipping. Although some determiners of tipping such as diner habits, stereotypes, service atmosphere, server’s actions, and bill size intensively are being searched, service quality as a determiner of tipping is still one of the most researched topics among others. However, ...

  15. AFM tip-sample convolution effects for cylinder protrusions

    Science.gov (United States)

    Shen, Jian; Zhang, Dan; Zhang, Fei-Hu; Gan, Yang

    2017-11-01

    A thorough understanding about the AFM tip geometry dependent artifacts and tip-sample convolution effect is essential for reliable AFM topographic characterization and dimensional metrology. Using rigid sapphire cylinder protrusions (diameter: 2.25 μm, height: 575 nm) as the model system, a systematic and quantitative study about the imaging artifacts of four types of tips-two different pyramidal tips, one tetrahedral tip and one super sharp whisker tip-is carried out through comparing tip geometry dependent variations in AFM topography of cylinders and constructing the rigid tip-cylinder convolution models. We found that the imaging artifacts and the tip-sample convolution effect are critically related to the actual inclination of the working cantilever, the tip geometry, and the obstructive contacts between the working tip's planes/edges and the cylinder. Artifact-free images can only be obtained provided that all planes and edges of the working tip are steeper than the cylinder sidewalls. The findings reported here will contribute to reliable AFM characterization of surface features of micron or hundreds of nanometers in height that are frequently met in semiconductor, biology and materials fields.

  16. Modular design of AFM probe with sputtered silicon tip

    DEFF Research Database (Denmark)

    Rasmussen, Peter; Thaysen, Jacob; Bouwstra, Siebe

    2001-01-01

    of the thin films constituting the cantilever. The AFM probe has an integrated tip made of a thick sputtered silicon layer, which is deposited after the probe has been defined and just before the cantilevers are released. The tips are so-called rocket tips made by reactive ion etching. We present probes...

  17. Clinical experience with a novel, irrigated, flexible tip ablation catheter in atrial fibrillation ablation.

    Science.gov (United States)

    Pezzulich, B; Taralli, S; Villata, G; Sori, P

    2015-04-01

    This paper aimed at assessing clinical efficacy and safety of a new fully irrigated and flexible tip catheter (Therapy™ Cool Flex™, St Jude Medical, St. Paul, MN, USA) in ablation of atrial fibrillation (AF). The study enrolled 117 consecutive patients with symptomatic AF who underwent for the first time a circumferential pulmonary vein isolation with a new irrigated and flexible tip catheter. All patients underwent successful pulmonary vein circumferential ablation. The mean procedure duration was 100 ± 27 min, total fluoroscopy time was 7.4 ± 5 min. The mean number of RF lesion was 139 ± 43 and the mean total RF time was 22.45 ± 3.9 min. Median follow-up was 665 ± 241 days. Through Kaplan-Meier analysis, overall event-free survival was 79.7%. In details, arrhythmia free survival was 85.4% in patients with persistent AF, 76% in paroxysmal AF and 75% in chronic AF. Three patients (2.5%) suffered from minor vascular complication (groin hematoma). Two patients (1.7%) suffered from pericardial effusion, treated with pericardiocentesis and with no sequelae. We did not observe any atrioesophageal fistula or pulmonary vein stenosis. The present study represents the largest cohort of patients receiving AF ablation with this new tip-flexible catheter. It demonstrated comparable efficacy to that previously reported, with a very low complication rate and procedural time. A head-to-head clinical trial would be necessary to address the relative efficacy of catheter type.

  18. Mental Toughness

    Science.gov (United States)

    Quinn, Tori; Cavanaugh, Lauren

    2017-01-01

    Mental toughness (MT) is defined as a set of attributes that allow an individual to persevere through difficult circumstances that ultimately can lead to successful outcomes. It is also a critical component of maximizing the performance of an athlete. These attributes assist with and promote a state of mind that enhances performance. A negative…

  19. Mental Illness

    Science.gov (United States)

    ... to situations and to people Alcohol or drug abuse Major changes in eating habits Sex drive changes Excessive anger, hostility or violence Suicidal thinking Sometimes symptoms of a mental health disorder appear as physical ... on Drug Abuse. http://www.drugabuse.gov/publications/principles-drug-addiction- ...

  20. Dual-tip-enhanced ultrafast CARS nanoscopy

    Science.gov (United States)

    Ballmann, Charles W.; Cao, Bin; Sinyukov, Alexander M.; Sokolov, Alexei V.; Voronine, Dmitri V.

    2014-08-01

    Coherent anti-Stokes Raman scattering (CARS) and, in particular, femtosecond adaptive spectroscopic techniques (FAST CARS) have been successfully used for molecular spectroscopy and microscopic imaging. Recent progress in ultrafast nano-optics provides flexibility in generation and control of optical near fields, and holds promise to extend CARS techniques to the nanoscale. In this theoretical study, we demonstrate ultrafast subwavelentgh control of coherent Raman spectra of molecules in the vicinity of a plasmonic nanostructure excited by ultrashort laser pulses. The simulated nanostructure design provides localized excitation sources for CARS by focusing incident laser pulses into subwavelength hot spots via two self-similar nanolens antennas connected by a waveguide. Hot-spot-selective dual-tip-enhanced CARS (2TECARS) nanospectra of DNA nucleobases are obtained by simulating optimized pump, Stokes and probe near fields using tips, laser polarization- and pulse-shaping. This technique may be used to explore ultrafast energy and electron transfer dynamics in real space with nanometre resolution.

  1. Dual-tip-enhanced ultrafast CARS nanoscopy

    CERN Document Server

    Ballmann, Charles W; Sinyukov, Alexander M; Sokolov, Alexei V; Voronine, Dmitri V

    2013-01-01

    Coherent anti-Stokes Raman scattering (CARS) and, in particular, femtosecond adaptive spectroscopic techniques (FAST CARS) have been successfully used for molecular spectroscopy and microscopic imaging. Recent progress in ultrafast nanooptics provides flexibility in generation and control of optical near fields, and holds promise to extend CARS techniques to the nanoscale. In this theoretical study, we demonstrate ultrafast subwavelentgh control of coherent Raman spectra of molecules in the vicinity of a plasmonic nanostructure excited by ultrashort laser pulses. The simulated nanostructure design provides localized excitation sources for CARS by focusing incident laser pulses into subwavelength hot spots via two self-similar nanolens antennas connected by a waveguide. Hot-spot-selective dual-tip-enhanced CARS (2TECARS) nanospectra of DNA nucleobases are obtained by simulating optimized pump, Stokes and probe near fields using tips, laser polarization- and pulse-shaping. This technique may be used to explore ...

  2. Development of Bend Sensor for Catheter Tip

    Science.gov (United States)

    Nagano, Yoshitaka; Sano, Akihito; Fujimoto, Hideo

    Recently, a minimally invasive surgery which makes the best use of the catheter has been becoming more popular. In endovascular coil embolization for a cerebral aneurysm, the observation of the catheter's painting phenomenon is very important to execute the appropriate manipulation of the delivery wire and the catheter. In this study, the internal bend sensor which consists of at least two bending enhanced plastic optical fibers was developed in order to measure the curvature of the catheter tip. Consequently, the painting could be more sensitively detected in the neighborhood of the aneurysm. In this paper, the basic characteristics of the developed sensor system are described and its usefulness is confirmed from the comparison of the insertion force of delivery wire and the curvature of catheter tip in the experiment of coil embolization.

  3. Twelve tips for facilitating Millennials' learning.

    Science.gov (United States)

    Roberts, David H; Newman, Lori R; Schwartzstein, Richard M

    2012-01-01

    The current, so-called "Millennial" generation of learners is frequently characterized as having deep understanding of, and appreciation for, technology and social connectedness. This generation of learners has also been molded by a unique set of cultural influences that are essential for medical educators to consider in all aspects of their teaching, including curriculum design, student assessment, and interactions between faculty and learners.  The following tips outline an approach to facilitating learning of our current generation of medical trainees.  The method is based on the available literature and the authors' experiences with Millennial Learners in medical training.  The 12 tips provide detailed approaches and specific strategies for understanding and engaging Millennial Learners and enhancing their learning.  With an increased understanding of the characteristics of the current generation of medical trainees, faculty will be better able to facilitate learning and optimize interactions with Millennial Learners.

  4. Twelve tips for early career medical educators.

    Science.gov (United States)

    Cristancho, Sayra; Varpio, Lara

    2016-01-01

    The first 10 years of career development pose unique challenges for MD- and PhD-trained faculty members working in medical education. These may include publishing peer-reviewed articles, winning grant funding, teaching, maintaining a clinical practice, and supporting professional communities both within and external to their institution. As the inaugural and current leaders of the ECME group in Canada, we have actively sought to better understand the challenges ECME faculty members face. We developed this understanding by surveying and tracking the qualitative reports of our ECME members, reviewing the (limited) literature available on ECME faculty members' experiences, and learning from our own experiences as ECME faculty and the advice shared by our own mentors. In this paper, we consolidate this knowledge into 12 tips for ECME faculty members. We suggest these tips will benefit both MD- and PhD-trained ECME faculty members as they strive for professional success.

  5. Cirrhotic patients with portal hypertension-related bleeding and an indication for early-TIPS: a large multicentre audit with real-life results.

    Science.gov (United States)

    Thabut, Dominique; Pauwels, Arnaud; Carbonell, Nicolas; Remy, Andre Jean; Nahon, Pierre; Causse, Xavier; Cervoni, Jean-Paul; Cadranel, Jean-François; Archambeaud, Isabelle; Bramli, Slim; Ehrhard, Florent; Ah-Soune, Philippe; Rostain, Florian; Pariente, Alexandre; Vergniol, Julien; Dupuychaffray, Jean-Pierre; Pelletier, Anne-Laure; Skinazi, Florence; Guillygomarc'h, Anne; Vitte, René-Louis; Henrion, Jean; Combet, Stéphanie; Rudler, Marika; Bureau, Christophe

    2017-09-13

    The Baveno VI consensus meeting concluded that an early TIPS must be considered in high-risk cirrhotic patients presenting with variceal bleeding (VB) (Child B + active bleeding at endoscopy or Child C10-13 patients). Whether this therapeutic approach is feasible in a real-life setting remains unclear. To determine (1) the proportion of patients eligible for early-TIPS among cirrhotic patients with VB, (2) the proportion of these patients who underwent early-TIPS placement and the main reasons for discarding TIPS, and (3) the outcomes of patients who experienced early-TIPS placement in a large, national, prospective, multicentre audit including academic and non-academic centres. All French centres recruiting gastrointestinal bleeding were invited to participate. All consecutive patients with cirrhosis and PHT-related bleeding were included. 964 patients were included (58 centres: 26 academic, 32 non-academic; patient characteristics: male sex, 77%; age, 59.6 ± 12.1 years; aetiologies of cirrhosis (alcoholic,viral/other, 67%/15%/18%); source of bleeding (EV/GV/other, 80/11/9%); active bleeding at endoscopy 34%; Child A 21%/B 44%/C 35%. Overall, 35% of the patients were eligible for early-TIPS, but only 6.8%, displaying less severe cirrhosis underwent early-TIPS placement. The main reason for discarding TIPS was a lack of availability. The actuarial probability of survival at one year was significantly increased in early-TIPS patients (85.7±0.07% vs 58.9±0.03%, p=0.04). The severity of liver disease was the only parameter independently associated with improved one-year survival. In this real-life study, one-third of the cirrhotic patients admitted for VB fulfilled the criteria for early-TIPS placement, whereas only 7% had access to TIPS. TIPS was restricted to patients displaying less severe cirrhosis. The severity of liver disease was the only parameter that influenced survival. Copyright © 2017. Published by Elsevier B.V.

  6. More Time Management Tips for Busy People

    Science.gov (United States)

    2014-10-01

    University (DAU) and also teaches for the Phoenix School of Advanced Studies. He is a retired naval officer and acquisition professional. No...interruptions. Consider Going Paperless Much of the information we get today is already in electronic form—e-mail, PDF files, Word and PowerPoint documents...long way down the path to becoming paperless , using tools like OneNote and two desktop monitors. All these tips require some initial investment of

  7. What Do You Mean, 'Tipping Point'?

    Science.gov (United States)

    van Nes, Egbert H; Arani, Babak M S; Staal, Arie; van der Bolt, Bregje; Flores, Bernardo M; Bathiany, Sebastian; Scheffer, Marten

    2016-12-01

    Over the past 10 years the use of the term 'tipping point' in the scientific literature has exploded. It was originally used loosely as a metaphor for the phenomenon that, beyond a certain threshold, runaway change propels a system to a new state. Although several specific mathematical definitions have since been proposed, we argue that these are too narrow and that it is better to retain the original definition. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Oracle Apex reporting tips and tricks

    CERN Document Server

    Bara, George

    2013-01-01

    Take advantage of all the exciting Reporting features of Oracle Application Express 4.2. Designed for a hands-on approach, this book contains in-depth practical guidelines from George Bara, a well-known Oracle Apex expert and blogger. From Classic to Interactive Reports, Web Services and Pdf Printing, "Oracle Apex Reporting Tips & Tricks" is a must-have for all database developers that want to make the most out of the Oracle Apex reporting engine.

  9. Robotic lobectomy: tips, pitfalls and troubleshooting.

    Science.gov (United States)

    Kocher, Gregor J; Schmid, Ralph A; Melfi, Franca M A

    2014-12-01

    The robotic approach in thoracic surgery has rapidly gained popularity in recent years. As with the introduction of any new technology, this warrants not only adaptation of the operative technique itself, but also the evolution of appropriate troubleshooting strategies. A selected number of helpful tips and technical procedural manoeuvres have been compiled to prevent intraoperative problems, as well as to overcome challenging situations that can arise during robotic lobectomies. In robotic surgery, as opposed to open surgery or video-assisted thoracic surgery, these tips serve an important purpose for the operating surgeon, as well as the entire surgical team involved in the procedure. All the assembled recommendations have proved their effectiveness and have been successfully used by the authors in many procedures. Furthermore, these manoeuvres have been found to be of great importance in the training and proctoring of thoracic surgeons, fellows and residents (bed-side assistants). This guide of clearly arranged tips and troubleshooting strategies offers surgeons a useful tool to overcome difficult situations in robotic lobectomy and preferably improve the reproducibility and safety of their procedures. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  10. Hydraulics characteristics of tipping sediment flushing gate.

    Science.gov (United States)

    Bong, C H J; Lau, T L; Ab Ghani, A

    2013-01-01

    This paper highlights a preliminary study on the potential of a tipping flush gate to be used in an open storm drain to remove sediment. The investigation was carried out by using a plasboard model of the tipping flush gate installed in a rectangular flume. A steady flow experiment was carried out to determine the discharge coefficients and also the outflow relationship of the tipping flush gate. The velocity produced by the gate at various distances downstream of the gate during flushing operation was measured using a flowmeter and the velocity at all the points was higher than the recommended self-cleansing design available in the literature. A preliminary experiment on the efficiency of flushing was conducted using uniform sediment with d50 sizes of 0.81, 1.53 and 4.78 mm. Results generally showed that the number of flushes required to totally remove the sediment from the initial position by a distance of 1 m increased by an average of 1.50 times as the sediment deposit bed thickness doubled. An equation relating the number of flushes required to totally remove the sediment bed for 1 m with the sediment bed deposit thickness was also developed for the current study.

  11. Email etiquette: guidelines for mental health nurses.

    Science.gov (United States)

    Cleary, Michelle; Freeman, Adele

    2005-03-01

    This note is about the use of email and its role in mental health settings. We anticipate that it may be of assistance to mental health nurses unfamiliar with the benefits and pitfalls of email and wanting to learn more about how to use it professionally and effectively. In mental health nursing, we pride ourselves on our interpersonal skills and being able to communicate. However, transferring these skills to an electronic medium is not always easy. Because many of us are self-taught, there is potential for email to be a hindrance rather than a help in the quest for good collegial relationships. In this note, we discuss some of the common situations that can arise when email use goes awry and provide some helpful tips for getting the most out of email. It is hoped that the information and checklist provided in this paper will strike a chord with many, encouraging discussion and promoting appropriate use of this form of communication.

  12. Scaling in light scattering by sharp conical metal tips

    CERN Document Server

    Pors, Anders; Bozhevolnyi, Sergey I

    2016-01-01

    Using the electrostatic approximation, we analyze electromagnetic fields scattered by sharp conical metal tips, which are illuminated with light polarized along the tip axis. We establish scaling relations for the scattered field amplitude and phase, whose validity is verified with numerical simulations. Analytic expressions for the wavelength, at which the scattered field near the tip changes its direction, and field decay near the tip extremity are obtained, relating these characteristics to the cone angle and metal permittivity. The results obtained have important implications to various tip-enhanced phenomena, ranging from Raman and scattering near-field imaging to photoemission spectroscopy and nano-optical trapping.

  13. Assessing physiological tipping points in response to ocean acidification

    Science.gov (United States)

    Dupont, S. T.; Dorey, N.; Lançon, P.; Thorndyke, M. S.

    2011-12-01

    Impact of near-future ocean acidification on marine invertebrates was mostly assessed in single-species perturbation experiment. Moreover, most of these experiments are short-term, only consider one life-history stage and one or few parameters. They do not take into account important processes such as natural variability and acclimation and evolutionary processes. In many studies published so far, there is a clear lack between the observed effects and individual fitness, most of the deviation from the control being considered as potentially negative for the tested species. However, individuals are living in a fluctuating world and changes can also be interpreted as phenotypic plasticity and may not translate into negative impact on fitness. For example, a vent mussel can survive for decades in very acidic waters despite a significantly reduced calcification compare to control (Tunnicliffe et al. 2009). This is possible thanks to the absence of predatory crabs as a result of acidic conditions that may also inhibit carapace formation. This illustrates the importance to take into account ecological interactions when interpreting single-species experiments and to consider the relative fitness between interacting species. To understand the potential consequence of ocean acidification on any given ecosystem, it is then critical to consider the relative impact on fitness for every interactive species and taking into account the natural fluctuation in environment (e.g. pH, temperature, food concentration, abundance) and discriminate between plasticity with no direct impact on fitness and teratology with direct consequence on survival. In this presentation, we will introduce the concept of "physiological tipping point" in the context of ocean acidification. This will be illustrated by some work done on sea urchin development. Embryos and larvae of the sea urchin Strongylocentrotus droebachiensis were exposed to a range of pH from 8.1 to 6.5. When exposed to low pH, growth

  14. In vitro thermotherapy and shoot-tip culture to eliminate Caper latent virus in Capparis spinosa

    Directory of Open Access Journals (Sweden)

    Laura Tomassoli

    2008-10-01

    Full Text Available Capparis spinosa plants in the Sicilian Islands, Italy, are frequently infected with Caper latent virus (CapLV. CapLV affects the vigour and longevity of caper plants and exacerbates the effect of other adverse biotic and abiotic factors. To have CapLV-free cuttings of caper for multiplication and new planting is therefore advantageous for a revival of this crop wherever it is cultivated. An improved procedure for the in vitro thermotherapy combined with the culture of the shoot tips of C. spinosa has been applied to caper material collected from Salina (Aeolian Archipelago and Pantelleria. More than of 60% (Salina and 90% (Pantelleria of the shoot tips survived, and 89–93% of the regenerated plantlets were CapLV-free when tested by RT-PCR. This is the first report on eliminating CapLV from caper plants.

  15. Evaluation of the new vacuum infiltration vitrification (viv) cryopreservation technique for native Australian plant shoot tips.

    Science.gov (United States)

    Funnekotter, Bryn; Whiteley, Susan E; Turner, Shane R; Bunn, Eric; Mancera, Ricardo L

    2015-01-01

    The application of a vacuum during the incubation in cryoprotective agents such as PVS2 allows for increased penetration, reducing total incubation times required before vitrification and post-cryopreservation regeneration is achieved. This study compared a conventional droplet-vitrification protocol to the new vacuum infiltration vitrification protocol in four Australian plant species. The new vacuum infiltration vitrification applied an 80 kPa vacuum during incubations in loading solution and PVS2. Infiltration of the cryoprotective agents into shoot tips was determined by differential scanning calorimetry measuring ice formation in the thermographs comparing a range of loading solution and PVS2 incubation times. The application of the vacuum infiltration vitrification technique resulted in a significantly reduced PVS2 incubation time for cryogenic survival and regeneration for all four species, reducing the time needed to adequately protect shoot tips by half to a quarter when compared to a conventional droplet-vitrification technique.

  16. Surviving a Suicide Attempt

    Directory of Open Access Journals (Sweden)

    Ahmed Al-Harrasi

    2016-09-01

    Full Text Available Suicide is a global phenomenon in all regions of the world affecting people of all age groups. It has detrimental consequences on patients, their families, and the community as a whole. There have been numerous risk factors described for suicide including mental illness, stressful life situations, loss of social support, and general despair. The association of suicide with Islam has not been extensively studied. The common impression from clinical practice is that being a practicing Muslim reduces the risk of suicide. Another factor associated with suicide is starting a patient on antidepressants. However, this has been questioned recently. This report describes a middle-aged man with depression and multiple social stressors who survived a serious suicide attempt. The discussion will focus on the factors that lead him to want to end his life and the impact of the assumed protective factors such as religious belief and family support on this act of self-harm. Such patients can be on the edge when there is an imbalance between risk factors (such as depression, insomnia, and psychosocial stressors and protective factors (like religious affiliation and family support. All physicians are advised to assess the suicide risk thoroughly in patients with depression regardless of any presumed protective factor.

  17. Surviving a Suicide Attempt.

    Science.gov (United States)

    Al-Harrasi, Ahmed; Al Maqbali, Mandhar; Al-Sinawi, Hamed

    2016-09-01

    Suicide is a global phenomenon in all regions of the world affecting people of all age groups. It has detrimental consequences on patients, their families, and the community as a whole. There have been numerous risk factors described for suicide including mental illness, stressful life situations, loss of social support, and general despair. The association of suicide with Islam has not been extensively studied. The common impression from clinical practice is that being a practicing Muslim reduces the risk of suicide. Another factor associated with suicide is starting a patient on antidepressants. However, this has been questioned recently. This report describes a middle-aged man with depression and multiple social stressors who survived a serious suicide attempt. The discussion will focus on the factors that lead him to want to end his life and the impact of the assumed protective factors such as religious belief and family support on this act of self-harm. Such patients can be on the edge when there is an imbalance between risk factors (such as depression, insomnia, and psychosocial stressors) and protective factors (like religious affiliation and family support). All physicians are advised to assess the suicide risk thoroughly in patients with depression regardless of any presumed protective factor.

  18. Quantification of tip-broadening in non-contact atomic force microscopy with carbon nanotube tips

    DEFF Research Database (Denmark)

    Meinander, Kristoffer; Jensen, Thomas N.; Simonsen, Soren B.

    2012-01-01

    Carbon nanotube terminated atomic force microscopy (AFM) probes have been used for the imaging of 5 nm wide surface supported Pt nanoclusters by non-contact (dynamic mode) AFM in an ultra-high vacuum. The results are compared to AFM measurements done with conventional Si-tips, as well as with tra......Carbon nanotube terminated atomic force microscopy (AFM) probes have been used for the imaging of 5 nm wide surface supported Pt nanoclusters by non-contact (dynamic mode) AFM in an ultra-high vacuum. The results are compared to AFM measurements done with conventional Si-tips, as well...... as with transmission electron microscopy images, which give accurate measures for cluster widths. Despite their ideal aspect ratio, tip-broadening is concluded to be a severe problem even when imaging with carbon nanotube tips, which overestimates the cluster width by several times the nominal width of the nanotube...... tip. This broadening is attributed to a bending of the carbon nanotubes, and not to pure geometrical factors, which coincidentally results in a significant improvement for relative height measurements of tightly spaced high aspect ratio structures, as compared to what can be achieved...

  19. Femtosecond Laser-Controlled Tip-to-Tip Assembly and Welding of Gold Nanorods.

    Science.gov (United States)

    González-Rubio, Guillermo; González-Izquierdo, Jesús; Bañares, Luis; Tardajos, Gloria; Rivera, Antonio; Altantzis, Thomas; Bals, Sara; Peña-Rodríguez, Ovidio; Guerrero-Martínez, Andrés; Liz-Marzán, Luis M

    2015-12-09

    Directed assembly of gold nanorods through the use of dithiolated molecular linkers is one of the most efficient methodologies for the morphologically controlled tip-to-tip assembly of this type of anisotropic nanocrystals. However, in a direct analogy to molecular polymerization synthesis, this process is characterized by difficulties in chain-growth control over nanoparticle oligomers. In particular, it is nearly impossible to favor the formation of one type of oligomer, making the methodology hard to use for actual applications in nanoplasmonics. We propose here a light-controlled synthetic procedure that allows obtaining selected plasmonic oligomers in high yield and with reaction times in the scale of minutes by irradiation with low fluence near-infrared (NIR) femtosecond laser pulses. Selective inhibition of the formation of gold nanorod n-mers (trimers) with a longitudinal localized surface plasmon in resonance with a 800 nm Ti:sapphire laser, allowed efficient trapping of the (n - 1)-mers (dimers) by hot spot mediated photothermal decomposition of the interparticle molecular linkers. Laser irradiation at higher energies produced near-field enhancement at the interparticle gaps, which is large enough to melt gold nanorod tips, offering a new pathway toward tip-to-tip welding of gold nanorod oligomers with a plasmonic response at the NIR. Thorough optical and electron microscopy characterization indicates that plasmonic oligomers can be selectively trapped and welded, which has been analyzed in terms of a model that predicts with reasonable accuracy the relative concentrations of the main plasmonic species.

  20. Deterministic Single Atom STM Tip Technology for Atomically Precise Manufacturing

    Science.gov (United States)

    Ballard, Joshua; Alexander, Justin; Radocea, Adrian; Bischof, Maia; Jaeger, David; Randall, John; Gorman, Brian; von Ehr, Jim; Reidy, Rick

    2011-03-01

    Deterministic tip fabrication for Scanning Tunneling Microscopy (STM) has long been an elusive goal, where the primary method of tip preparation usually includes significant ``tip conditioning'' once the tip has been incorporated into the STM. We have developed a process for generating reproducible single atom tips (SATs) with a small radius of curvature (r.o.c.) of less than 10nm. First, W(111) or W(110) tips are sputter sharpened using a self-limiting process to yield with r.o.c. of SAT is formed. Transmission Electron Microscopy is used to verify that after field evaporation the r.o.c. remains small. Correlations between FIM and tip performance in STM are determined, and long term STM stability is discussed.

  1. Probability of noise- and rate-induced tipping.

    Science.gov (United States)

    Ritchie, Paul; Sieber, Jan

    2017-05-01

    We propose an approximation for the probability of tipping when the speed of parameter change and additive white noise interact to cause tipping. Our approximation is valid for small to moderate drift speeds and helps to estimate the probability of false positives and false negatives in early-warning indicators in the case of rate- and noise-induced tipping. We illustrate our approximation on a prototypical model for rate-induced tipping with additive noise using Monte Carlo simulations. The formula can be extended to close encounters of rate-induced tipping and is otherwise applicable to other forms of tipping. We also provide an asymptotic formula for the critical ramp speed of the parameter in the absence of noise for a general class of systems undergoing rate-induced tipping.

  2. Arctic tipping points in an Earth system perspective.

    Science.gov (United States)

    Wassmann, Paul; Lenton, Timothy M

    2012-02-01

    We provide an introduction to the volume The Arctic in the Earth System perspective: the role of tipping points. The terms tipping point and tipping element are described and their role in current science, general debates, and the Arctic are elucidated. From a wider perspective, the volume focuses upon the role of humans in the Arctic component of the Earth system and in particular the envelope for human existence, the Arctic ecosystems. The Arctic climate tipping elements, the tipping elements in Arctic ecosystems and societies, and the challenges of governance and anticipation are illuminated through short summaries of eight publications that derive from the Arctic Frontiers conference in 2011 and the EU FP7 project Arctic Tipping Points. Then some ideas based upon resilience thinking are developed to show how wise system management could ease pressures on Arctic systems in order to keep them away from tipping points.

  3. Preparation of platinum/iridium scanning probe microscopy tips

    DEFF Research Database (Denmark)

    Sørensen, Alexis Hammer; Hvid, U.; Mortensen, M.W.

    1999-01-01

    material being etched is platinum/iridium (10%) the influence of the stop phase of the ac current terminating each pulse in the second etching is found to be negligible, while in the case of second etching of tungsten wires it is important to break the pulse in a certain phase to avoid formation of a thick...... of platinum from the wire surface and hereby give rise to "etching" of the wire. In the second etching blunt tips become sharp while tips which are already sharp apparently stay sharp. Therefore, the second etching scheme with pulses separated by pauses is found to be a very important factor...... for the production of sharp tips. After being etched the tips are ready for use in scanning tunneling microscopes, or they may be bent to form integrated tip/cantilever systems in ordinary commercial atomic force microscopes, being applicable as tapping mode tips and as electrostatic force microscopy tips. ©1999...

  4. Thermally enhanced field emission from a laser-illuminated tungsten tip: temperature rise of tip

    Energy Technology Data Exchange (ETDEWEB)

    Lee, M.J.G.; Reifenberger, R.; Robins, E.S.; Lindenmayr, H.G.

    1980-09-01

    Thermal field emission of electrons has been investigated from a tungsten field emitter illuminated by the focused beam of a laser operating at a range of wavelengths in the visible region of the spectrum. The temperature rise of the tip is determined as a function of the displacement of the focused spot of light along the shank, and of its polarization. The experimental data are compared with the results of a first-principle calculation of the temperature rise, based on an experimental investigation of the intensity distribution within the focused spot of light and of the geometry of the field emitter. The comparison shows that when the laser beam is focused close to the tip the temperature rise is anomalously large; evidence is presented which suggests that the temperature rise of the tip is substantially enhanced by diffraction effects.

  5. Comparison of Step Tip Type and Split Tip Type Hemodialysis Catheter: HemoGlide Versus the HemoSplit

    Energy Technology Data Exchange (ETDEWEB)

    Park, Mi Hyun [Dankook University Hospital, Cheonan (Korea, Republic of); Shin, Byung Seok [Chungnam National University, Daejeon (Korea, Republic of)

    2009-08-15

    To evaluate the results and complications of the step tip type and split tip type tunneled hemodialysis catheters. Between March 2008 and December 2008, a total of 147 tunneled hemodialysis catheters of step tip (n=89) and split tip (n=58) type were placed in 126 patients to perform hemodialysis. We evaluated the number of catheterization days, as well as complications with respect to catheter tip types. A tunneled hemodialysis catheter was placed successfully in all cases. The duration of catheterization ranged from 7 to 180 days (mean 68, total catheter days: 10,504 days). A significantly higher complication rate was observed in the step tip type (n=23) as compared to the split tip type (n=4) (p=0.004), especially due to catheter dysfunction and catheter laceration. Five cases of catheter-related infection (3.4%, 0.48/1000 catheter days) were observed. Placement of the tunneled hemodialysis catheter of step tip type and spit tip type were performed safely. However, the split tip type is more useful because of the greater rate of complication in step tip type

  6. Perceptions of Mental Retardation and Mental Illness.

    Science.gov (United States)

    Caruso, David R.; Hodapp, Robert M.

    1988-01-01

    Open-ended questions of college students (N=60) indicated students clearly differentiated between the mentally retarded and mentally ill. Mental retardation was characterized by physical stigmata, brain damage, developmental delays, and cognitive deficits; mental illness by emotional lability due to environmental, hereditary, or mixed factors.…

  7. Investigation on Blind Tip Reconstruction Errors Caused by Sample Features

    Directory of Open Access Journals (Sweden)

    Jiahuan Wan

    2014-12-01

    Full Text Available Precision measurements of a nanoscale sample surface using an atomic force microscope (AFM require a precise quantitative knowledge of the 3D tip shape. Blind tip reconstruction (BTR, established by Villarrubia, gives an outer bound with larger errors if the tip characterizer is not appropriate. In order to explore the errors of BTR, a series of simulation experiments based on a conical model were carried out. The results show that, to reconstruct the tip precisely, the cone angle of the tip characterizer must be smaller than that of the tip. Furthermore, the errors decrease as a function of the tip cone angle and increase linearly with the sample radius of curvature, irrespective of the tip radius of curvature. In particular, for sharp (20 nm radius and blunt (80 nm radius tips, the radius of curvature of the tip characterizer must be smaller than 5 nm. Based on these simulation results, a local error model of BTR was established. The maximum deviation between the errors derived from the model and the simulated experiments is 1.22 nm. Compared with the lateral resolution used in the above simulated experiments (4 nm/pixel, it is valid to ignore the deviations and consider the local error model of BTR is indeed in quantitative agreement with the simulation results. Finally, two simulated ideal structures are proposed here, together with their corresponding real samples. The simulation results show they are suitable for BTR.

  8. Three-dimensional dendrite-tip morphology at low undercooling

    Energy Technology Data Exchange (ETDEWEB)

    Karma, Alain [Physics Department and Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts 02115 (United States); Lee, Youngyih H. [Physics Department and Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts 02115 (United States); Plapp, Mathis [Physics Department and Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts 02115 (United States)

    2000-04-01

    We investigate the three-dimensional morphology of the dendrite tip using the phase-field method. We find that, for low undercoolings, this morphology is ostensibly independent of anisotropy strength except for a localized shape distortion near the tip that only affects the value of the tip radius {rho} [which is crudely approximated by {rho}{approx_equal}(1-{alpha}){rho}{sub Iv} where {rho}{sub Iv} is the Ivantsov tip radius of an isothermal paraboloid with the same tip velocity and {alpha} is the stiffness anisotropy]. The universal tip shape, which excludes this distortion, is well fitted by the form z=-r{sup 2}/2+A{sub 4}r{sup 4} cos 4{phi} where |z| is the distance from the tip and all lengths are scaled by {rho}{sub Iv}. This fit yields A{sub 4} in the range 0.004-0.005 in good quantitative agreement with the existing tip morphology measurements in succinonitrile [LaCombe et al., Phys. Rev. E 52, 2778 (1995)], which are reanalyzed here and found to be consistent with a single cos 4{phi} mode nonaxisymmetric deviation from a paraboloid. Moreover, the fin shape away from the tip is well fitted by the power law z=-a|x|{sup 5/3} with a{approx_equal}0.68. Finally, the characterization of the operating state of the dendrite tip is revisited in the light of these results. (c) 2000 The American Physical Society.

  9. Regulation of H+ Extrusion and Cytoplasmic pH in Maize Root Tips Acclimated to a Low-Oxygen Environment.

    Science.gov (United States)

    Xia, J. H.; Roberts, JKM.

    1996-05-01

    We tested the hypothesis that H+ extrusion contributes to cytoplasmic pH regulation and tolerance of anoxia in maize (Zea mays) root tips. We studied root tips of whole seedlings that were acclimated to a low-oxygen environment by pretreatment in 3% (v/v) O2. Acclimated root tips characteristically regulate cytoplasmic pH near neutrality and survive prolonged anoxia, whereas nonacclimated tips undergo severe cytoplasmic acidosis and die much more quickly. We show that the plasma membrane H+-ATPase can operate under anoxia and that net H+ extrusion increases when cytoplasmic pH falls. However, at an external pH near 6.0, H+ extrusion contributes little to cytoplasmic pH regulation. At more acidic external pH values, net H+ flux into root tips increases dramatically, leading to a decrease in cytoplasmic pH and reduced tolerance of anoxia. We present evidence that, under these conditions, H+ pumps are activated to partly offset acidosis due to H+ influx and, thereby, contribute to cytoplasmic pH regulation and tolerance of anoxia. The regulation of H+ extrusion under anoxia is discussed with respect to the acclimation response and mechanisms of intracellular pH regulation in aerobic plant cells.

  10. [Plastic micro-tips for drug delivery].

    Science.gov (United States)

    Muslija, A; Guber, A E; Heckele, M; Herrmann, D; Pfleging, W; Schaller, Th

    2002-01-01

    Removal or exact transfer of minimum substance volumes from reservoirs or microfluidic systems may be accomplished by means of miniaturized tips with integrated through-going capillaries. Applications in biomedical engineering, e.g. for the application of drugs, or in life sciences, e.g. equipping of microarrays, require the use of disposable plastic products for hygienic reasons and reasons of costs. For this purpose, a method to fabricate microtips out of plastic by doublesided molding has been developed at the Forschungszentrum Karlsruhe.

  11. Tip-over Prevention: Adaptive Control Development

    Science.gov (United States)

    2015-05-30

    and tested on an iRobot Packbot and a Segway RMP 440. Experimental results show that the controllers are able to stabilize the robot under a variety...VALIDATION The adaptive roll and pitch controllers, or advanced control, were implemented on both an iRobot Packbot and a Segway RMP 440, each equipped...measure. Threshold for tip-over warning set to 0.38. 1) Segway RMP 440: Figure 5 demonstrates the advanced control active on the Segway RMP440. The

  12. Turbine blade tip gap reduction system

    Science.gov (United States)

    Diakunchak, Ihor S.

    2012-09-11

    A turbine blade sealing system for reducing a gap between a tip of a turbine blade and a stationary shroud of a turbine engine. The sealing system includes a plurality of flexible seal strips extending from a pressure side of a turbine blade generally orthogonal to the turbine blade. During operation of the turbine engine, the flexible seal strips flex radially outward extending towards the stationary shroud of the turbine engine, thereby reducing the leakage of air past the turbine blades and increasing the efficiency of the turbine engine.

  13. Semi-empirical crack tip analysis

    Science.gov (United States)

    Chudnovsky, A.; Ben Ouezdon, M.

    1988-01-01

    Experimentally observed crack opening displacements are employed as the solution of the multiple crack interaction problem. Then the near and far fields are reconstructed analytically by means of the double layer potential technqiue. Evaluation of the effective stress intensity factor resulting from the interaction of the main crack and its surrounding crazes in addition to the remotely applied load is presented as an illustrative example. It is shown that crazing (as well as microcracking) may constitute an alternative mechanism to Dugdale-Berenblatt models responsible for the cancellation of the singularity at the crack tip.

  14. Higiene mental

    Directory of Open Access Journals (Sweden)

    Francisco Gomez Pinzón

    1940-08-01

    Full Text Available El número cada día mayor de enfermos mentales, que hace “contraste con  la evidente disminución de enfermedades infecto-contagiosas, -lograda a favor de los modernos métodos de curación y profilaxis- es un hecho que está siendo comprobado “en todos los países civilizados y que constituye motivo de justificada alarma para cuantos se preocupan por cuestiones del orden biológico y social”

  15. Improved recovery of cryotherapy-treated shoot tips following thermotherapy of in vitro-grown stock shoots of raspberry (Rubus idaeus L.).

    Science.gov (United States)

    Wang, Qiaochun; Valkonen, Jari P T

    2009-01-01

    Raspberry bushy dwarf virus (RBDV) can be efficiently eradicated from raspberry plants (Rubus idaeus) by a procedure combining thermotherapy and cryotherapy. However, the bottleneck of this procedure is that, following thermotherapy, cryopreserved shoot tips become chlorotic during regrowth and eventually die after several subcultures. In addition, survival of heat-treated stock shoots and recovery of cryopreserved shoot tips following thermotherapy are low. The present study focused towards improving regrowth of cryopreserved raspberry shoot tips following thermotherapy. Results showed that preconditioning stock shoots with salicylic acid (SA; 0.01-0.1 mM) markedly increased survival of stock shoots after 4 weeks of thermotherapy. Regrowth of cryopreserved shoot tips following thermotherapy was also significantly enhanced when SA (0.05-0.1 mM) was used for preconditioning stock shoots. Addition of either Fe-ethylenediaminetetracetic acid (Fe-EDTA, 50 mg per L) or Fe-ethylenediaminedi(o)hydroxyphenylacetic acid (Fe-EDDHA, 50 mg per L) to post-culture medium strongly promoted regrowth and totally prevented chlorosis of shoots regenerated from cryopreserved shoot tips following thermotherapy. Using the parameters optimized in the present study, about 80 percent survival of heat-treated stock shoots and about 33 percent regrowth of cryopreserved shoot tips following thermotherapy were obtained. Morphology of plants regenerated from cryopreserved shoot tips following thermotherapy was identical to that of control plants, based on observations of leaf shape and size, internode length and plant height. Optimization of the thermotherapy procedure followed by cryotherapy will facilitate the wider application of this technique to eliminate viruses which can invade meristems.

  16. Turbine-blade tip clearance and tip timing measurements using an optical fiber bundle sensor

    Science.gov (United States)

    Garcia, Iker; Beloki, Josu; Zubia, Joseba; Durana, Gaizka; Aldabaldetreku, Gotzon

    2013-04-01

    Traditional limitations of capacitive, inductive or discharging probe sensor for tip timing and tip clearance measurements are overcome by reflective intensity modulated optical fiber sensors. This paper presents the signals and results corresponding to a one stage turbine rig which rotor has 146 blades, obtained from a transonic wind-tunnel test. The probe is based on a trifurcated bundle of optical fibers that is mounted on turbine casing. It is composed of a central illuminating fiber that guides the light from a laser to the turbine blade, and two concentric rings of receiving fibers that collect the reflected light. Two photodetectors turn this reflected light signal from the receiving rings into voltage. The electrical signals are acquired and saved by a high-sample-rate oscilloscope. In tip clearance calculations the ratio of the signals provided by each ring of receiving fibers is evaluated and translated into distance. In the case of tip timing measurements, only one of the signals is considered to get the arrival time of the blade. The differences between the real and theoretical arrival times of the blades are used to obtain the deflections amplitude. The system provides the travelling wave spectrum, which presents the average vibration amplitude of the blades at a certain nodal diameter. The reliability of the results in the turbine rig testing facilities suggests the possibility of performing these measurements in real turbines under real working conditions.

  17. Dynamic of cold-atom tips in anharmonic potentials

    Science.gov (United States)

    Menold, Tobias; Federsel, Peter; Rogulj, Carola; Hölscher, Hendrik; Fortágh, József

    2016-01-01

    Background: Understanding the dynamics of ultracold quantum gases in an anharmonic potential is essential for applications in the new field of cold-atom scanning probe microscopy. Therein, cold atomic ensembles are used as sensitive probe tips to investigate nanostructured surfaces and surface-near potentials, which typically cause anharmonic tip motion. Results: Besides a theoretical description of this anharmonic tip motion, we introduce a novel method for detecting the cold-atom tip dynamics in situ and real time. In agreement with theory, the first measurements show that particle interactions and anharmonic motion have a significant impact on the tip dynamics. Conclusion: Our findings will be crucial for the realization of high-sensitivity force spectroscopy with cold-atom tips and could possibly allow for the development of advanced spectroscopic techniques such as Q-control. PMID:28144505

  18. Effects of plastic anisotropy on crack-tip behaviour

    DEFF Research Database (Denmark)

    Legarth, Brian Nyvang; Tvergaard, Viggo; Kuroda, Mitsutoshi

    2002-01-01

    For a crack in a homogeneous material the effect of plastic anisotropy on crack-tip blunting and on the near-tip stress and strain fields is analyzed numerically. The full finite strain analyses are carried out for plane strain under small scale yielding conditions, with purely symmetric mode I...... loading remote from the crack-tip. In cases where the principal axes of the anisotropy are inclined to the plane of the crack it is found that the plastic zones as well as the stress and strain fields just around the blunted tip of the crack become non-symmetric. In these cases the peak strain...... on the blunted tip occurs off the center line of the crack, thus indicating that the crack may want to grow in a different direction. When the anisotropic axes are parallel to the crack symmetry is retained, but the plastic zones and the near-tip fields still differ from those predicted by standard isotropic...

  19. Functionalized Akiyama tips for magnetic force microscopy measurements

    Science.gov (United States)

    Stiller, Markus; Barzola-Quiquia, José; Esquinazi, Pablo D.; Sangiao, Soraya; De Teresa, José M.; Meijer, Jan; Abel, Bernd

    2017-12-01

    In this work we have used focused electron beam induced deposition of cobalt to functionalize atomic force microscopy Akiyama tips for application in magnetic force microscopy. The grown tips have a content of  ≈ 90~% Co after exposure to ambient air. The magnetic tips were characterized using energy dispersive x-ray spectroscopy and scanning electron microscopy. In order to investigate the magnetic properties, current loops were prepared by electron beam lithography. Measurements at room temperature as well as 4.2~K were carried out and the coercive field of  ≈6.8 mT of the Co tip was estimated by applying several external fields in the opposite direction of the tip magnetization. Magnetic Akiyama tips open new possibilities for wide-range temperature magnetic force microscopy measurements.

  20. Aperiodicity Correction for Rotor Tip Vortex Measurements

    Science.gov (United States)

    Ramasamy, Manikandan; Paetzel, Ryan; Bhagwat, Mahendra J.

    2011-01-01

    The initial roll-up of a tip vortex trailing from a model-scale, hovering rotor was measured using particle image velocimetry. The unique feature of the measurements was that a microscope was attached to the camera to allow much higher spatial resolution than hitherto possible. This also posed some unique challenges. In particular, the existing methodologies to correct for aperiodicity in the tip vortex locations could not be easily extended to the present measurements. The difficulty stemmed from the inability to accurately determine the vortex center, which is a prerequisite for the correction procedure. A new method is proposed for determining the vortex center, as well as the vortex core properties, using a least-squares fit approach. This approach has the obvious advantage that the properties are derived from not just a few points near the vortex core, but from a much larger area of flow measurements. Results clearly demonstrate the advantage in the form of reduced variation in the estimated core properties, and also the self-consistent results obtained using three different aperiodicity correction methods.

  1. Ten tips for authors of scientific articles.

    Science.gov (United States)

    Hong, Sung-Tae

    2014-08-01

    Writing a good quality scientific article takes experience and skill. I propose 'Ten Tips' that may help to improve the quality of manuscripts for scholarly journals. It is advisable to draft first version of manuscript and revise it repeatedly for consistency and accuracy of the writing. During the drafting and revising the following tips can be considered: 1) focus on design to have proper content, conclusion, points compliant with scope of the target journal, appropriate authors and contributors list, and relevant references from widely visible sources; 2) format the manuscript in accordance with instructions to authors of the target journal; 3) ensure consistency and logical flow of ideas and scientific facts; 4) provide scientific confidence; 5) make your story interesting for your readers; 6) write up short, simple and attractive sentences; 7) bear in mind that properly composed and reflective titles increase chances of attracting more readers; 8) do not forget that well-structured and readable abstracts improve citability of your publications; 9) when revising adhere to the rule of 'First and Last' - open your text with topic paragraph and close it with resolution paragraph; 10) use connecting words linking sentences within a paragraph by repeating relevant keywords.

  2. DO SLOVENIAN DEALERS USE TECHNIQUES FOR INCREASING THEIR TIPS?

    Directory of Open Access Journals (Sweden)

    Andrej Raspor

    2016-05-01

    Full Text Available In 1996 Michael Lynn introduced the idea that restaurant managers could increase tips for their waiters and thus increase turnover by training the waiters to engage tip-enhancing behaviours. Since then, the list of tip-enhancing behaviours has expanded. Therefore the potential to increase tips is more accessible. The purpose of this paper was to examine how Slovenian dealers use strategies to increase their tips. We tested fourteen techniques to increase tips. The study was carried out among 473 gaming employees, 279 of which are dealers, in the Slovenian gaming industry, in order to find out how they use these techniques and which of them can bring about an increase in their tips. The study showed that Slovenian dealers mostly do not use these techniques, and that the dealers who do use them tend to receive tips more often. The findings imply that managers and employees should be informed of these techniques in order to increase tips and their overall income. Practical implications are that we suggest that management considers these ideas for increasing flexibility and reducing the cost of work: (1 informing dealers on ways of increasing tips, (2 including the acquisition of this specific knowledge in their career plans, (3 carrying out a reform of the reward system which would include tips. Social implications will be shown in a higher gaming revenue. It is very likely – as shown in our research – that employees will receive higher wages as these will be topped up by tips. The state, in turn, will collect more taxes.

  3. Quantitative Atomic Force Microscopy with Carbon Monoxide Terminated Tips

    OpenAIRE

    Sun, Zhixiang; Boneschanscher, Mark P.; Swart, Ingmar; Vanmaekelbergh, Daniel; Liljeroth, Peter

    2011-01-01

    Noncontact atomic force microscopy (AFM) has recently progressed tremendously in achieving atomic resolution imaging through the use of small oscillation amplitudes and well-defined modification of the tip apex. In particular, it has been shown that picking up simple inorganic molecules (such as CO) by the AFM tip leads to a well-defined tip apex and to enhanced image resolution. Here, we use the same approach to study the three-dimensional intermolecular interaction potential between two mol...

  4. Good Mental Health

    Science.gov (United States)

    ... Mental Health This information in Spanish ( en español ) Good mental health Nutrition and mental health Exercise and mental health ... a friend. Return to top More information on Good mental health Read more from womenshealth.gov Action Steps for ...

  5. Energy Saver: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-09-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  6. Energy Savers: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-12-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  7. On the origin of planetary-scale tipping points.

    Science.gov (United States)

    Lenton, Timothy M; Williams, Hywel T P

    2013-07-01

    Tipping points are recognised in many systems, including ecosystems and elements of the climate system. But can the biosphere as a whole tip and, if so, how? Past global tipping points were rare and occurred in the coupled planetary-scale dynamics of the Earth system, not in the local-scale dynamics of its weakly interacting component ecosystems. Yet, evolutionary innovations have triggered past global transformations, suggesting that tipping point theory needs to go beyond bifurcations and networks to include evolution. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Dependence of electric field on STM tip preparation

    DEFF Research Database (Denmark)

    Huang, D.H.; Grey, Francois; Aono, M.

    1998-01-01

    Voltage pulses applied between an STM tip and a surface can modify the surface on the nanometer scale due to electric-field-induced evaporation. However, at present, different groups have achieved surface modification with quite different bias conditions, and it is still difficult to obtain high...... reproducibility in such experiments. In this paper, we measure the tip displacement during a pulse at constant tunnelling current, and deduce that the electric field produced by the pulse depends in a systematic way on tip preparation, The results show how differences in tip preparation can be a major source...

  9. Fatigue crack propagation and cyclic deformation at a crack tip

    Science.gov (United States)

    Kang, T. S.; Liu, H. W.

    1974-01-01

    The fatigue crack propagation relation da/dN = f(R) Delta K squared can be derived with three assumptions: small-scale yielding, material homogeneity, and that crack tip stresses and strains are not strongly affected by plate thickness. The function f(R) is a constant at a given stress ratio, R. The effects of plate thickness and stress ratio on crack tip deformation and fatigue crack growth in 2024-T351 aluminum alloy were studied. High Delta K level in a thin specimen causes crack tip necking. Necking is more pronounced at high stress ratio. Necking causes high maximum strain near a crack tip and fast crack growth rate.

  10. Callus induction and regeneration via shoot tips of Dendrocalamus hamiltonii

    National Research Council Canada - National Science Library

    Zang, Qiaolu; Zhou, Ling; Zhuge, Fei; Yang, Haiyun; Wang, Xiaoqin; Lin, Xinchun

    2016-01-01

    By using shoot tips as explants, various media and culture conditions for callus induction and proliferation, shoot differentiation, root induction and plantlet transplantation to develop an efficient...

  11. Research progress in TIPS shunt dysfunction and recanalization

    Directory of Open Access Journals (Sweden)

    WANG Tingting

    2015-11-01

    Full Text Available Transjugular intrahepatic portosystemic shunt (TIPS is widely used in the treatment of cirrhotic portal hypertension and its associated complications. However, postoperative shunt dysfunction has been an important factor restricting the clinical application of TIPS. This article summarizes the use of shunt, the incidence of shunt dysfunction after TIPS, preventive measures and diagnostic methods for shunt dysfunction, and indications and techniques of shunt recanalization, in order to enhance our knowledge of shunt dysfunction and recanalization, which could further improve the efficacy of TIPS for cirrhotic portal hypertension.

  12. Energy Savers Tips on Saving Energy& Money at Home

    Energy Technology Data Exchange (ETDEWEB)

    2003-06-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances

  13. Integrated Turbine Tip Clearance and Gas Turbine Engine Simulation

    Science.gov (United States)

    Chapman, Jeffryes W.; Kratz, Jonathan; Guo, Ten-Huei; Litt, Jonathan

    2016-01-01

    Gas turbine compressor and turbine blade tip clearance (i.e., the radial distance between the blade tip of an axial compressor or turbine and the containment structure) is a major contributing factor to gas path sealing, and can significantly affect engine efficiency and operational temperature. This paper details the creation of a generic but realistic high pressure turbine tip clearance model that may be used to facilitate active tip clearance control system research. This model uses a first principles approach to approximate thermal and mechanical deformations of the turbine system, taking into account the rotor, shroud, and blade tip components. Validation of the tip clearance model shows that the results are realistic and reflect values found in literature. In addition, this model has been integrated with a gas turbine engine simulation, creating a platform to explore engine performance as tip clearance is adjusted. Results from the integrated model explore the effects of tip clearance on engine operation and highlight advantages of tip clearance management.

  14. Microneedles array with biodegradable tips for transdermal drug delivery

    Science.gov (United States)

    Iliescu, Ciprian; Chen, Bangtao; Wei, Jiashen; Tay, Francis E. H.

    2008-12-01

    The paper presented an enhancement solution for transdermal drug delivery using microneedles array with biodegradable tips. The microneedles array was fabricated by using deep reactive ion etching (DRIE) and the biodegradable tips were made to be porous by electrochemical etching process. The porous silicon microneedle tips can greatly enhance the transdermal drug delivery in a minimum invasion, painless, and convenient manner, at the same time; they are breakable and biodegradable. Basically, the main problem of the silicon microneedles consists of broken microneedles tips during the insertion. The solution proposed is to fabricate the microneedle tip from a biodegradable material - porous silicon. The silicon microneedles are fabricated using DRIE notching effect of reflected charges on mask. The process overcomes the difficulty in the undercut control of the tips during the classical isotropic silicon etching process. When the silicon tips were formed, the porous tips were then generated using a classical electrochemical anodization process in MeCN/HF/H2O solution. The paper presents the experimental results of in vitro release of calcein and BSA with animal skins using a microneedle array with biodegradable tips. Compared to the transdermal drug delivery without any enhancer, the microneedle array had presented significant enhancement of drug release.

  15. Energy Savers: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-05-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  16. Do people tip strategically, to improve future service? Theory and evidence

    OpenAIRE

    Azar, Ofer H.

    2007-01-01

    A central question about tipping is whether people tip strategically, to improve future service, or only because tipping is a social norm. I present a theoretical model that incorporates psychological utility associated with tipping (because it is a social norm) and allows tipping to be motivated also by future service considerations. The model predicts that if future service is a reason for tipping, the sensitivity of tips to service quality should be higher for repeating customers than for ...

  17. Tips for Dealing with Behavior Management Issues

    Science.gov (United States)

    Bechtel, Pamela A.; Stevens, Lisa A.; Brett, Christine E. W.

    2012-01-01

    The increased diversity of today's students included in P-12 physical education classes creates new challenges in behavior management for physical education teachers. Currently more students with identified at-risk behaviors, as well as more students with physical or mental disabilities, are placed in general physical education classes. This…

  18. Local Facilitation May Cause Tipping Points on a Landscape Level Preceded by Early-Warning Indicators.

    Science.gov (United States)

    Xu, Chi; Van Nes, Egbert H; Holmgren, Milena; Kéfi, Sonia; Scheffer, Marten

    2015-10-01

    Positive biotic interactions play a significant role in shaping ecological communities. We used an individual-based model to demonstrate that plant facilitation on a microscale may cause ecosystem shifts on a landscape scale that can be announced by generic early-warning indicators. Recruitment of woody plants in harsh environments such as drylands often depends on nurse plants that ameliorate stressful conditions and facilitate the establishment of seedlings under their canopy. We found that these facilitative interactions may cause a treeless and a woodland state to be alternative stable states on a landscape scale if nurse plant effects are strong and if the environment is harsh enough to make facilitation necessary for seedling survival. A corollary is that under such conditions environmental change can bring drylands to tipping points for woody plant encroachment or woodland collapse. We show that the proximity of tipping points may be indicated by slowness of recovery of woody vegetation cover from small perturbations as well as by elevated temporal and spatial autocorrelation and variance. These signs are known to be indicators of critical slowing down. This is the first demonstration that the systemic phenomena of tipping points, announced by critical slowing down as a warning signal, may plausibly arise from microscale individual interactions, such as plant facilitation.

  19. Regeneration of Dioscorea floribunda plants from cryopreserved encapsulated shoot tips: effect of plant growth regulators.

    Science.gov (United States)

    Mandal, B B; Ahuja-Ghosh, Sangeeta

    2007-01-01

    The encapsulation-dehydration protocol for the cryopreservation of in vitro shoot tips of Dioscorea floribunda was optimized. Maximum survival of 87% was obtained when overnight pretreatment with 0.3 M sucrose was followed by encapsulation, preculture in 0.75 M sucrose for 4 d, dehydration in a laminar air flow for 5.5 h, quenching in liquid nitrogen and thawing at 40 degrees C. During recovery growth, 29% shoot formation was obtained when cryopreserved shoot tips were initially cultured for 25 d on a medium with 1.5 mg per liter (-1) BAP, 0.2 mg per liter(-1) NAA and 0.2 mg per liter(-1) GA3 followed by culturing for 15 d on a medium with reduced BAP (1 mg per liter(-1)) but increased NAA (0.5 mg per liter(-1)) and GA3 (0.3 mg per liter(-1)). Finally, transfer on to a medium with further reduced doses of BAP (0.05 mg per liter(-1)) and NAA (0.15 mg per liter(-1)) but without GA3 stimulated production of fully grown plantlets. All plants regenerated without callus formation. Modification of post-thaw culture media with plant growth regulators was essential for regrowth of shoot tips to plantlets.

  20. Male professional footballers' experiences of mental health difficulties and help-seeking.

    Science.gov (United States)

    Wood, Susan; Harrison, Lesley K; Kucharska, Jo

    2017-05-01

    Male professional footballers (soccer) represent an at-risk population of developing mental health difficulties and not accessing professional support. One in four current footballers report mental health difficulties. Higher prevalence is reported after retirement. This qualitative study aimed to provide in-depth insight into male professional footballers' lived experiences of mental health difficulties and help-seeking. Seven participants were interviewed. Data were analysed using interpretative phenomenological analysis. One superordinate theme emerged; 'Survival'. This related to survival in the professional football world, of mental health difficulties and after transition into the 'real world'. Six subordinate themes are explored alongside literature pertaining to male mental health, identity, injury, transition, and emotional development. Shame, stigma, fear and level of mental health literacy (knowledge of mental health and support) were barriers to help-seeking. Support for professional footballers' mental wellbeing requires improvement. Recommendations are made for future research, mental health education and support.

  1. Is this normal? Assessing mental health in young people.

    Science.gov (United States)

    McGorry, Patrick D; Goldstone, Sherilyn

    2011-03-01

    Mental ill-health is a key health issue facing young Australians today. While the physical health of young people has improved in recent decades, their mental health appears to have worsened. Mental health and substance use disorders now account for over 50% of the burden of disease in the 15-25 years age group, and 75% of mental health disorders that will affect people across the lifespan will have emerged for the first time by the age of 25 years. This article provides the general practitioner with key factors in assessing the young person with a mental illness: when to worry and what the early stages of mental illness look like; and provides guidance and tips for effective treatment. Mental ill-health in young people is all too often accepted as a 'normal' feature of adolescence. However, the short and long term consequences of mental illness include impaired social functioning, poor educational achievement, substance abuse, self harm, suicide and violence. Distinguishing between what represents transitory and normative changes in behaviour and disturbances that may represent the early signs of the onset of a potentially serious mental illness is difficult, particularly in young people, where emotional disturbance and distress is such a common experience. The primary goal of initial assessment is not to make a definitive diagnosis but rather to assess risk and the need for clinical care. The GP has an important role to play in longitudinal assessment and ongoing review, and facilitating access to treatment and mobilising support networks.

  2. Women and Mental Health

    Science.gov (United States)

    ... Chats with Experts Clinical Trials Share Women and Mental Health Overview Mental disorders can affect women and men ... biological and psychosocial factors that may impact the mental health of both women and men. Warning Signs Women ...

  3. Common Mental Health Issues

    Science.gov (United States)

    Stock, Susan R.; Levine, Heidi

    2016-01-01

    This chapter provides an overview of common student mental health issues and approaches for student affairs practitioners who are working with students with mental illness, and ways to support the overall mental health of students on campus.

  4. Rural Mental Health

    Science.gov (United States)

    ... Rural Health Topics & States Topics View more Rural Mental Health There is a significant need for mental health ... action to prevent suicides? Where can I find mental health statistics for rural populations? The Substance Abuse and ...

  5. Mental Labels and Tattoos

    Science.gov (United States)

    Hyatt, I. Ralph

    1977-01-01

    Discusses the ease with which mental labels become imprinted in our system, six basic axioms for maintaining negative mental tattoos, and psychological processes for eliminating mental tattoos and labels. (RK)

  6. Teen Mental Health

    Science.gov (United States)

    ... worthless could be warning signs of a mental health problem. Mental health problems are real, painful, and sometimes severe. You ... things that could harm you or others Mental health problems can be treated. To find help, talk ...

  7. [Predictable tip suture techniques in rhinoplasty].

    Science.gov (United States)

    Papel, I D

    2010-09-01

    Recontouring the nasal tip in rhinoplastic procedures has generated a wide range of surgical techniques. These range from aggressive cartilage resection, division, grafting, or suture methods. Each of these categories contains many variations described in hundreds of publications. The goal of this communication is to describe a predictable, reproducible technique that can be used in a wide variety of rhinoplasty operations. Based on pre-existing anatomy variations of this technique can be adopted. The author described the basic technique in 2004 [1].The cornerstone of the technique is a predictable method of narrowing the interdomal space utilizing a suture technique. This procedure employs a pair of permanent sutures designed to minimize distortion, valve impingement and overcorrection. It can be performed through intranasal or external approaches. This paper will define the wide interdomal space, describe the technique, and demonstrate the efficacy of the technique in 250 rhinoplasty procedures. In addition, variations of the technique for specific goals will be shown.

  8. Cosmogenesis and the tipping pencil analogy

    Science.gov (United States)

    Adler, Ronald J.

    2012-05-01

    We present a toy model and scenario for cosmogenesis which provides an interesting rationale for the spatial flatness of the universe. The basic assumptions are that the cosmological scale factor obeys the standard Friedmann equation of general relativistic cosmology and that the equation is dominated by a cosmological constant term and a curvature term. The dynamics of the universe is then similar to that of a tipping pencil. The scale factor cannot remain at an unstable initial value of zero and must increase according to the uncertainty principle. If it is also assumed that the universe expands at the minimum asymptotic rate consistent with the uncertainty principle, the result is exact spatial flatness, rather than the near flatness obtained in standard inflation theory.

  9. Twelve tips to improve bedside teaching.

    Science.gov (United States)

    Ramani, Subha

    2003-03-01

    Bedside teaching has long been considered the most effective method to teach clinical skills and communication skills. Despite this belief, the frequency of bedside rounds is decreasing and it is believed that this is a major factor causing a sharp decline in trainees' clinical skills. Several barriers appear to contribute to this lack of teaching at the bedside and have been discussed extensively in the literature. Concern about trainees' clinical skills has led organizations such as the American Council for Graduate Medical Education (ACGME) and the WHO Advisory Committee on Medical training to recommend that training programs should increase the frequency of bedside teaching in their clinical curricula. Although obstacles to bedside teaching are acknowledged, this article in the '12 tips' series is a detailed description of teaching strategies that could facilitate a return to the bedside for clinical teaching.

  10. Pearls for publishing papers: Tips and tricks

    Directory of Open Access Journals (Sweden)

    Karalikkattil T Ashique

    2016-01-01

    Full Text Available With the stringent regulations from various academic bodies making it desirable for a post graduate resident to have submitted an original article prior to appearance for their exams or those working in teaching institutions to have published articles to claim credit for applying for promotions and private practitioners to increase their visibility on the academic front, everyone is on a publishing spree. In this article, we attempt to elucidate the processes involved in publication; approaching it in a systematic and practical manner, incorporating some tips and tricks. This collection of pearls is aimed to serve as a beginner′s guide to scientific writing and publications. The pearls cover assorted topics like- benefits of publications, collecting resources, various tools available and technical processes related to how a manuscript is processed.

  11. Magnetic nondestructive testing of rotor blade tips

    Science.gov (United States)

    Cardelli, E.; Faba, A.; Marsili, R.; Rossi, G.; Tomassini, R.

    2015-05-01

    This paper deals with a particular magnetic nondestructive technique applied to the control of the position of the steel blades in rotating parts of turbines and engines. The working principle is based on a bridge of four identical magneto-resistive sensors. One sensor is placed near the blades, and the change in magnetic field produced by a permanent magnet and deviated by the change in position of the blade is detected by the sensor bridge. The position of the sensor is indicated, via dedicated FEM simulations, in order to have high sensitivity to the position change and high output signal. The accuracy and effectiveness of the proposed method are shown by experimental tests carried out in our laboratories. In particular, the tests indicate that the proposed magnetic nondestructive technique can be used in an almost large velocity range, and for quite different values of blade tip. The method seems also promising for the detection of blade vibrations.

  12. Tipping Points: Early warning and wishful thinking

    Science.gov (United States)

    Ditlevsen, Peter

    2010-05-01

    Climate changes and especially the risk of rapid and irreversible changes is of great socioeconomic concern. Abrupt transitions from one statistically steady state to another occur in many complex dynamical systems. Common for these are that crossing a critical threshold can lead to a structural change of the system. This is mathematically described as a bifurcation, which gives the hope that the generic dynamical behavior at bifurcation- or tipping points may be observed even with only imperfect knowledge of the dynamics of the system. It would be especially useful if early warning signals prior to a climate transition could be identified, and perhaps even prevented. The two generic characteristics of the approach to a bifurcation point is increased variance of the observed signal, following from the fluctuation-dissipation theorem and the corresponding increased autocorrelation, related to critical slow down. These two signals are connected, and the detection of only one and not the other, cannot be taken as a sign of an approaching tipping point. This is contrary to what was recently claimed (Dakos et al., PNAS, 105, 14308-14312, 2008; Scheffer et al.,Nature, 461, 53-59, 2009). We shall in the following show this, assess the statistical significance and examine these two signals for the most pronounced observed climate jumps, the Dansgaard-Oeschger events and the termination of the last glacial period. The conclusions drawn is that these most probably are not generated by bifurcations: They are noise induced transitions without early warning signals. This means that it is necessary to understand the full non-linear structure of the climate system, including assessing the influence by an external perturbation (such as increased greenhouse gas concentrations) on the short time scale fluctuations (noise), which might push the system into a different (quasi-)stationary state.

  13. Tip shift in the zero inertia powertrain

    Energy Technology Data Exchange (ETDEWEB)

    Serrarens, A.F.A.; Vroemen, B.G.; Veldpaus, F.E.; Veenhuizen, P.A.

    2002-07-01

    For any transmission type the vehicle's responsiveness during large and/or fast engine speed shifts may appear reluctant or even counteractive. This is caused by unwanted inertial torques stemming from accelerating or decelerating the rotating elements within the engine and transmission. Reminiscent of comparable behaviour seen in aircraft jet-propulsion, this phenomenon is also referred to as 'jet-start'. To overcome this behaviour, a CVT powertrain is augmented with a powersplitting planetary gear stage and compact steel flywheel. The new transmission-coded zero inertia (ZI) powertrain-seamlessly combines two contradictive features: the driveability in terms of the pedal-to-wheel response is greatly improved and a large leap towards optimal fuel economy can be made. The latter is achieved by cruising the vehicle at extremely low engine speeds owing to the large ratio-coverage of the CVT. As for the driveability, the flywheel acts as a peak shaver. During engine speed shifts it delivers power at (semi-) pedal kick down (downshift) and absorbs kinetic energy of the engine sided powertrain elements at pedal back-out (upshift). In this paper, the behaviour of the ZI system is evaluated in 'tip-shift' mode. In field experiments the tip-shift in a VW Bora test vehicle with ZI powertrain is compared with a commercially available Mini One with CVT. A test panel of 10 people drove the vehicles, executed predefined tasks and evaluated their findings. The results of these experiments are also reported in this paper. (orig.)

  14. [Mental Space Navigation and Mental Time Travel].

    Science.gov (United States)

    Kawamura, Mitsuru

    2017-11-01

    We examined patients with mental space navigation or mental time travel disorder to identify regions in the brain that may play a critical role in mental time travel in terms of clinical neuropsychology. These regions included the precneus, posterior cingulate gyrus, retrosplenial cortex, and hippocampus, as well as the orbitofrontal cortex: the anterior and posterior medial areas were both shown to be important in this process. Further studies are required to define whether these form a network for mental time travel.

  15. Tip loss correction for actuator / Navier Stokes computations

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Sørensen, Jens Nørkær; Mikkelsen, Robert Flemming

    2004-01-01

    The new tip loss correction, initially developed for ID BEM computations [1], is now extended to 2D Actuator Disc / Navier-Stokes (AD/NS) computations and 3D Actuator Line / Navier-Stokes (AL/NS) computations. As shown in the paper, the tip loss correction is an important and necessary step...

  16. 29 CFR 531.59 - The tip wage credit.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false The tip wage credit. 531.59 Section 531.59 Labor... § 531.59 The tip wage credit. In determining compliance with the wage payment requirements of the Act... such employee in the workweek for which the wage payment is made. This credit is in addition to any...

  17. Specific inhibition of Mdm2-mediated neddylation by Tip60

    DEFF Research Database (Denmark)

    Dohmesen, Christoph; Koeppel, Max; Dobbelstein, Matthias

    2007-01-01

    Tip60 is a histone acetyl transferase (HAT) and a cofactor of transcription, but also an interaction partner of the Mdm2 oncoprotein. The functional consequences of this interaction are only partially understood and were further explored in this study. We found that Tip60 is capable of selectively...

  18. Trade and Industrial Policy Strategies (TIPS) Core Grant - Phase IV ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Trade and Industrial Policy Strategies (TIPS) Core Grant - Phase IV. Established in 1996, Trade and Industrial Policy Strategies (TIPS) is an organization that coordinates a network of researchers that seeks to provide the Government of South Africa, civil society and the region with independent advice on economic policy, ...

  19. Using High-Content Imaging to Analyze Toxicological Tipping ...

    Science.gov (United States)

    Presentation at International Conference on Toxicological Alternatives & Translational Toxicology (ICTATT) held in China and Discussing the possibility of using High Content Imaging to Analyze Toxicological Tipping Points Slide Presentation at International Conference on Toxicological Alternatives & Translational Toxicology (ICTATT) held in China and Discussing the possibility of using High Content Imaging to Analyze Toxicological Tipping Points

  20. Living the "Tipping Point": Concurrent Teacher Leader and Principal Preparation

    Science.gov (United States)

    Hambright, W. Grant; Franco, Myra Suzanne

    2008-01-01

    In the 2007 edition of the NCPEA Yearbook, Zigler and Allen allude to the principalship and its associated training as being at a "tipping point," a reference to Malcom Gladwell's (2000) book, "The Tipping Point: How Little Things Can Make a Difference" (2007, p. 139). Zigler and Allen contend the current principal paradigm is…

  1. Toxicological Tipping Points (NTP-NIEHS seminar) | Science ...

    Science.gov (United States)

    Description in attached presentation slides file. Presentation at NTP Laboratory Seminar series in RTP, NC on taking a new look at the Toxicological Tipping Points and how they compare to the high-content imaging (HCL) data to find tipping points?

  2. Prevent Tipping Furniture from Injuring or Killing Young Children

    Science.gov (United States)

    ... this! Home » Health Tips » Child Emergencies Prevent Tipping Furniture from Injuring or Killing Young Children The nation’s ... a child — killed by a piece of a furniture, appliance or a television falling on them. “It ...

  3. Pilot biobased bekers : tips, achtergrondinformatie en evaluatie van de pilot

    NARCIS (Netherlands)

    Bolck, C.H.

    2015-01-01

    Dit document is primair bedoeld als hulpmiddel bij de inkoop en/of aanbesteding van de verzorging van koffie in kantoorgebouwen. In het document is een negen tal praktische tips verwerkt. Dit zijn tips die in de pilot zijn meegegeven aan de beoordelaars van de offertes: professionals actief in

  4. Anisotropic Adhesion Properties of Triangular-Tip-Shaped Micropillars

    KAUST Repository

    Kwak, Moon Kyu

    2011-06-01

    Directional dry adhesive microstructures consisting of high-density triangular-tip-shaped micropillars are described. The wide-tip structures allow for unique directional shear adhesion properties with respect to the peeling direction, along with relatively high normal adhesion. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Numerical simulation of tip clearance impact on a pumpjet propulsor

    Directory of Open Access Journals (Sweden)

    Lin Lu

    2016-05-01

    Full Text Available Numerical simulation based on the Reynolds Averaged Navier–Stokes (RANS Computational Fluid Dynamics (CFD method had been carried out with the commercial code ANSYS CFX. The structured grid and SST k–ω turbulence model had been adopted. The impact of non-condensable gas (NCG on cavitation performance had been introduced into the Schnerr and Sauer cavitation model. The numerical investigation of cavitating flow of marine propeller E779A was carried out with different advance ratios and cavitation numbers to verify the numerical simulation method. Tip clearance effects on the performance of pumpjet propulsor had been investigated. Results showed that the structure and characteristics of the tip leakage vortex and the efficiency of the propulsor dropped more sharply with the increase of the tip clearance size. Furthermore, the numerical simulation of tip clearance cavitation of pumpjet propulsor had been presented with different rotational speed and tip clearance size. The mechanism of tip clearance cavitation causing a further loss of the efficiency had been studied. The influence of rotational speed and tip clearance size on tip clearance cavitation had been investigated.

  6. Efficient regeneration of plants from shoot tip explants of ...

    African Journals Online (AJOL)

    Dendrobium densiflorum Lindl. is one of the horticulturally important orchids of Nepal due to its beautiful yellowish flower and medicinal properties. The present study was carried out for plant regeneration from shoot tip explants of D. densiflorum by tissue culture technique. The shoot tip explants of this species, obtained ...

  7. Cryopreservation of in vitro -grown shoot tips of apricot ( Prunus ...

    African Journals Online (AJOL)

    In vitro grown apricot (Prunus armeniaca L.) cv. El-Hamawey shoot tips were successfully cryopreserved using an encapsulation-dehydration procedure. Shoot tips were encapsulated in calcium-alginate beads before preculture on woody plant (WP) medium supplemented with different sucrose concentrations; 0.1, 0.3, 0.5, ...

  8. Effectiveness of closed suction drainage tip culture in hip arthroplasty.

    Science.gov (United States)

    Park, Jai Hyung; Shon, Hyun Chul; Kim, Ji Wan; Park, Se Jin; Ko, Taeg Su; Park, Jong Hyon

    2016-01-01

    The aim of the present study was to investigate the correlation between bacterial growth in closed suction drainage tip culture and periprosthetic joint infection (PJI). Retrospective review included 256 patients who had undergone hip arthroplasty in which the closed suction drainage tip was cultured. Follow-up periods were longer than a year. Sensitivity, specificity, positive predictive value, and negative predictive value were calculated in order to determine the significance of closed suction drainage tip culture in early diagnosis of infection. Patients with positive culture test were monitored to determine the effect of change in antibiotics on treatment of early infection. Eight of the 13 infections showed positive results from closed suction drainage tip culture. Eleven of the 243 non-infectious cases showed positive results after closed suction drainage tip culture (psuction drainage tip culture was 61.5%, with a specificity of 95.5%. Positive and negative predictive values were 42.1% and 97.9%, respectively. Systemic antibiotics were administered according to in vitro sensitivity of bacteria cultured from closed suction drainage tip in 13 of 19 positive culture cases. No statistically significant difference in infection risk was observed between the antibiotics group and the group to which antibiotics were not administered (p=0.51). Closed suction drainage tip culture can aid in the early detection of infection.

  9. Times required for cavity preparation using ultrasonic tips

    NARCIS (Netherlands)

    Özcan, Mutlu; Nergiz, Ibrahim; Pfeiffer, Peter; Tütüncü, Rengin

    1999-01-01

    Poster for: Date/Event/Venue: 10.03.99-13.03.99 77th General Session & Exhibition of the IADR Vancouver The purpose of this study was to evaluate the required time for opening the proximal cavities using three ultrasonic tips of different sizes and fine diamond inlay bur followed by ultrasonic tip.

  10. Trade and Industrial Policy Strategies (TIPS) - Phase III | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    As a result, TIPS will broaden its thematic agenda to include, in addition to trade analysis, the Real Economy Study and a program of work on the economics of education. Recently, TIPS successfully competed with other policy institutions in Southern Africa to host the new Southern African Development Research Network ...

  11. Improving Your Health: Tips for African American Men and Women

    Science.gov (United States)

    ... A Guide for Teenagers Talking with Patients about Weight Loss: Tips for Primary Care Providers Tips to Help You Get Active Benefits Starting Physical Activity Keep Moving Clinical Trials Understanding Adult Overweight and Obesity Using the World Around You to Stay Healthy ...

  12. Ten Timeless Tips for Keeping on Top of Teaching Technology

    Science.gov (United States)

    Poling, Devereaux A.; LoSchiavo, Frank M.

    2014-01-01

    We provide tips for helping psychology faculty effectively seek, select, and place new technology into pedagogical practice. We also provide tips to help psychology departments position themselves for a future that includes teaching technologies that have not yet been created. Instead of discussing today's top innovations in teaching (which…

  13. Necks formed between Oxidized Silicon Tips and Ice Surfaces for Negative Tip Bias

    Science.gov (United States)

    Slaughterbeck, C. R.; Pittenger, B.; Cook, D. J.; Fain, S. C., Jr.

    1996-03-01

    The interaction of ice with other surfaces has many consequences in environmental physics and chemistry.(J.G. Dash, H. Fu, J.S. Wettlaufer, Rep. Prog. Phys. 58), 115 (1995). A special scanning force microscope is used to infer the formation of ice necks when oxidized silicon probe tips are withdrawn at 5 x 10-5 m/s from the surface of ice at -8 or -10 degC. These necks are formed at a tip bias of -10 Volts, but not +10 Volts.(C.R. Slaughterbeck, E.W. Kukes, B. Pittenger, D.J. Cook, P.C. Williams, V.L. Eden, S.C. Fain, Jr., J. Vac. Sci. Tech. A (in press).) The necks form in pure water vapor atmospheres as well as in partial N2 atmospheres. The necks formed under these conditions are typically several hundred nanometers long, indicating significant mass transport. Similar necks were not observed at room temperature for similar biases between mica surfaces and a tip in an undersaturated water vapor atmosphere. Mobile surface ions may be responsible for the neck growth we observe at the surface of ice. This work supported by NSF grant DMR 91-19701.

  14. Spread of fluid: Role of tip configurations in needles

    DEFF Research Database (Denmark)

    Gomes, Silvana; Drakidis, Alexandros Dimitrios; Silva, Patricia

    2017-01-01

    data were obtained after injecting 0.3 mL of fluid into a foamed polymer model with a velocity of 2 mm/s. The spread area and the depth were determined for 3 different types of hypodermic needles: Single channel needles with bevel tip and blunt tip and a needle with conical tip and 3 internal channels......During the injection of a fluid in a tissue model, the fluid might be affected by the needle tip configuration and the number of channels. Thus, the objective of the present work is to observe the influence of different needle tips and number of channels on the spread of a fluid. Fluid distribution...

  15. Nonlinear Aerodynamics and the Design of Wing Tips

    Science.gov (United States)

    Kroo, Ilan

    1991-01-01

    The analysis and design of wing tips for fixed wing and rotary wing aircraft still remains part art, part science. Although the design of airfoil sections and basic planform geometry is well developed, the tip regions require more detailed consideration. This is important because of the strong impact of wing tip flow on wing drag; although the tip region constitutes a small portion of the wing, its effect on the drag can be significant. The induced drag of a wing is, for a given lift and speed, inversely proportional to the square of the wing span. Concepts are proposed as a means of reducing drag. Modern computational methods provide a tool for studying these issues in greater detail. The purpose of the current research program is to improve the understanding of the fundamental issues involved in the design of wing tips and to develop the range of computational and experimental tools needed for further study of these ideas.

  16. Near tip strain evolution of a growing fatigue crack

    Directory of Open Access Journals (Sweden)

    M.-L. Zhu

    2015-07-01

    Full Text Available Near tip full-field strains in a growing fatigue crack have been studied in situ using the Digital Image Correlation (DIC technique in a compact tension specimen of stainless steel 316L under tension-tension cyclic loading. An error analysis of displacements and strains has been carried out, and the results show that the precision of displacements and strains in the wake of the crack is worse than that in front of the crack. A method for the determination of crack tip location is proposed for the DIC analysis. Strain ratchetting is observed ahead of the growing fatigue crack tip and found to be dependent on the distance to the crack tip; whilst normal strains appear to stabilise behind the crack tip.

  17. Encapsulated tips for reliable nanoscale conduction in scanning probe technologies.

    Science.gov (United States)

    Bhaskaran, Harish; Sebastian, Abu; Drechsler, Ute; Despont, Michel

    2009-03-11

    Nanoscale tip apexes of conducting cantilever probes are important enablers for several conducting probe technologies that require reliable long-term operation, while preserving the nanoscale integrity of the tip apex. In this paper, the concept of an encapsulated tip with a nanoscale conducting core is presented. A method to fabricate such tips on conducting silicon microcantilevers is described. Long-term conduction and wear reliability of these nanoscale tips are evaluated systematically, and their ability to operate for sliding distances greater than 2 m in conduction and 11 m in wear on amorphous carbon is demonstrated. These results are expected to have an impact on the future of conducting probe-based technologies such as probe-based nanometrology, data storage and nanolithography.

  18. Thermoelectric measurements using different tips in atomic force microscopy

    Science.gov (United States)

    Kushvaha, S. S.; Hofbauer, W.; Loke, Y. C.; Singh, Samarendra P.; O'Shea, S. J.

    2011-04-01

    We use conducting atomic force microscopy (AFM) in ultra high vacuum to measure the thermoelectric power of Au, Pt, and 3,4,9,10-perylene tetracarboxylic dianhydride (PTCDA) films. Tips coated with thick (1200 nm) Pt films or highly doped diamond film give reproducible data. The thermoelectric power of metal junctions formed with diamond tips is high but dominated by the diamond material thus making diamond tips of limited applicability in thermovoltage AFM. Pt coated tips on Au or Pt films gives small thermovoltage signal, making quantitative analysis of the thermopower on metal sample problematic. The thermovoltage AFM technique appears best suited to study organic thin films and the thermoelectric power of 1.5 nm and 2 nm thick PTCDA deposited on Au measured with Pt tips is -342 and -372 μV/K, respectively. The negative sign indicates that the lowest unoccupied molecular orbital level dominates electrical transport.

  19. Gyroscopic Stability of Open Tipped Match Style Rifle Bullets

    CERN Document Server

    Courtney, Elya R

    2014-01-01

    Earlier work has produced formulas for predicting stability of rifle bullets of near uniform density and also for plastic-tipped rifle bullets. These formulas have been shown to be accurate to within 5%. However, the original Miller twist formula for metal bullets of near uniform density underestimates the stability of match style open tipped rifle bullets having a significant empty volume in the tip. This paper presents a new formula for accurately estimating the stability of these open tipped match style rifle bullets from parameters easily obtained such as the bullet mass, length, and depth of the empty space in the tip. The formula is tested by measuring the aerodynamic drag vs. predicted stability of several bullets over a range of stabilities.

  20. Mechanisms for enlarging lesion size during irrigated tip radiofrequency ablation

    DEFF Research Database (Denmark)

    Petersen, Helen Høgh; Roman-Gonzalez, Javier; Johnson, Susan B

    2004-01-01

    INTRODUCTION: Irrigated tip radiofrequency ablation of cardiac arrhythmias was developed to increase the size of the radiofrequency-induced lesion, since cooling of the electrode tip allows use of higher power settings. The purpose of this study was to determine if the increased lesion size during...... and in vivo canine left ventricles were ablated. In vitro closed loop tip and showerhead irrigated tip catheters were compared. In vitro and in vivo showerhead tip catheters irrigated with solutions having different ionic content were compared. We found no difference in lesion size for closed loop...... and showerhead-type catheters (998 +/- 345 vs. 811 +/- 313 mm(3) during power-controlled ablation and 227 +/- 76 vs 318 +/- 127 mm(3) during temperature-controlled ablation). For irrigation with liquids having increasing ionic strength we found a decrease in lesion volume in vitro (361 +/- 249 vs. 812 +/- 229 mm...

  1. Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX

    Energy Technology Data Exchange (ETDEWEB)

    Yamagata, Kazutsune, E-mail: kyamagat@ncc.go.jp [Department of Molecular Oncology Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan); Kitabayashi, Issay [Department of Molecular Oncology Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan)

    2009-12-25

    Sirt1 appear to be NAD(+)-dependent deacetylase that deacetylates histones and several non-histone proteins. In this study, we identified Sirt1 as a physical interaction partner of Tip60, which is a mammalian MYST-type histone acetyl-transferase that specifically acetylates histones H2A and H4. Although Tip60 also acetylates DNA damage-specific histone H2A variant H2AX in response to DNA damage, which is a process required for appropriate DNA damage response, overexpression of Sirt1 represses Tip60-mediated acetylation of H2AX. Furthermore, Sirt1 depletion by RNAi causes excessive acetylation of H2AX, and enhances accumulation of {gamma}-ray irradiation-induced MDC1, BRCA1, and Rad51 foci in nuclei. These findings suggest that Sirt1 functions as negative regulator of Tip60-mediated acetylation of H2AX. Moreover, Sirt1 deacetylates an acetylated Tip60 in response to DNA damage and stimulates proteasome-dependent Tip60 degradation in vivo, suggesting that Sirt1 negatively regulates the protein level of Tip60 in vivo. Sirt1 may thus repress excessive activation of the DNA damage response and Rad51-homologous recombination repair by suppressing the function of Tip60.

  2. Effect of pubescence tip on soybean resistance to lepidopteran insects.

    Science.gov (United States)

    Hulburt, David J; Boerma, H Roger; All, John N

    2004-04-01

    DNA marker analysis has mapped a quantitative trait locus for soybean, Glycine max (L.) Merr., resistance to the corn earworm, Helicoverpa zea (Boddie) (Lepidoptera: Noctuidae), on the USDA soybean genetic linkage map near the classical gene Pb, which conditions pubescence tip. This study was initiated to determine the effect of pubescence tip on resistance to H. zea larvae and to examine the effect on beet armyworm, Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae), and soybean looper, Pseudoplusia includens (Walker) (Lepidoptera: Noctuidae), larvae. The effect of blunt (pb) and sharp (Pb) pubescence tip was tested in antixenosis and antibiosis bioassays on H. zea, S. exigua, and P. includens larvae with near-isolines and insect-resistant and -susceptible genotypes differing in pubescence tip morphology. Sharp pubescence tip significantly reduced defoliation (antixenosis) from H. zea, S. exigua, and P. includens and weight gain (antibiosis) of H. zea. The weight gain of P. includens was unaffected, and S. exigua weight gain was significant for one pair of near-isolines differing in pubescence tip but not the other. The results indicate that sharp pubescence tip would be beneficial to introgress into elite soybean germplasm due to its association with resistance to H. zea, S. exigua, and P. includens.

  3. Efficacy of air/water syringe tip sterilization.

    Science.gov (United States)

    Inger, M; Bennani, V; Farella, M; Bennani, F; Cannon, R D

    2014-03-01

    Dental procedures involve contact between instruments and the patient's tissues, blood or saliva. This study evaluated the efficacy of the standardized sterilization of non-disposable air/water syringe tips and corrosion and contaminant build-up in these tips. The bacterial contamination of single-use and multiple-use non-disposable air/water syringe tips after routine use and sterilization was compared to that of single-use disposable tips by microbial culturing on PCA and blood agar plates. The effect of flushing the syringe tips prior to sterilization was also measured. The amount of corrosion in single-use and multiple-use non-disposable syringes was measured by SEM and EDS analyses. Non-disposable syringe tips had significantly (p Sterilization of non-disposable air/water syringes is not completely effective and rinsing, or the number of uses, does not affect the effectiveness of sterilization. There may be a lower risk of cross-infection from the use of disposable air/water syringe tips, instead of non-disposable ones. © 2014 Australian Dental Association.

  4. Investigation on tip enhanced Raman spectra of graphene.

    Science.gov (United States)

    Li, Xinjuan; Liu, Yanqi; Zeng, Zhuo; Wang, Peijie; Fang, Yan; Zhang, Lisheng

    2018-02-05

    Tip-enhanced Raman scattering (TERS) is a promising analytical approach for some two-dimensional materials and offers the possibility to correlate imaging and chemical data. Tip-enhanced Raman spectra of graphene are discussed in some details, including substrate, gap between tip-apex and sample surface as well as Ag-nanowire. The TERS spectra give special emphasis to the possibility of TERS tip to induce a large number of defects only while got the tip attached to sample surface. Then the dependence of the TERS spectra of graphene and gap between the probe tip and sample surface was studied, and distribution features of electromagnetic (EM) field around tip were also simulated by finite-difference time-domain (FDTD). The Raman signal enhancement of graphene was further discussed with respect to experimental data. Furthermore, the Ag-nanowire as a nano-antenna could significantly enhance the weak Raman signal of D-band of monolayer graphene is shown, and the TERS spectra of graphene with regard to different regions of Ag-nanowires (endpoints, body) were obtained toward investigating into the distribution of electromagnetic field. Copyright © 2017. Published by Elsevier B.V.

  5. Nose tip refinement using interdomal suture in caucasian nose

    Directory of Open Access Journals (Sweden)

    Pasinato, Rogério

    2012-01-01

    Full Text Available Introduction: Refinement of the nose tip can be accomplished by a variety of techniques, but currently, the use of sutures in the nasal tip with conservative resection of the alar cartilage is the most frequently recommended approach. Objective: To classify the nasal tip and to demonstrate the interdomal suture applied to nasal tip refinement in the Caucasian nose, as well as to provide a simple and practical presentation of the surgical steps. Method: Development of surgical algorithm for nasal tip surgery: 1. Interdomal suture (double binding suture, 2. Interdomal suture with alar cartilage weakening (cross-hatching, 3. Interdomal suture with cephalic removal of the alar cartilage (McIndoe technique based on the nasal tip type classification. This classification assesses the interdomal distance (angle of domal divergence and intercrural distance, domal arch width, cartilage consistency, and skin type. Interdomal suture is performed through endonasal rhinoplasty by basic technique without delivery (Converse-Diamond technique under local anesthesia Conclusion: This classification is simple and facilitates the approach of surgical treatment of the nasal tip through interdomal suture, systematizing and standardizing surgical maneuvers for better refinement of the Caucasian nose.

  6. A Blade Tip Timing Method Based on a Microwave Sensor

    Directory of Open Access Journals (Sweden)

    Jilong Zhang

    2017-05-01

    Full Text Available Blade tip timing is an effective method for blade vibration measurements in turbomachinery. This method is increasing in popularity because it is non-intrusive and has several advantages over the conventional strain gauge method. Different kinds of sensors have been developed for blade tip timing, including optical, eddy current and capacitance sensors. However, these sensors are unsuitable in environments with contaminants or high temperatures. Microwave sensors offer a promising potential solution to overcome these limitations. In this article, a microwave sensor-based blade tip timing measurement system is proposed. A patch antenna probe is used to transmit and receive the microwave signals. The signal model and process method is analyzed. Zero intermediate frequency structure is employed to maintain timing accuracy and dynamic performance, and the received signal can also be used to measure tip clearance. The timing method uses the rising and falling edges of the signal and an auto-gain control circuit to reduce the effect of tip clearance change. To validate the accuracy of the system, it is compared experimentally with a fiber optic tip timing system. The results show that the microwave tip timing system achieves good accuracy.

  7. Study of the twinned dendrite tip shape II: Experimental assessment

    Energy Technology Data Exchange (ETDEWEB)

    Salgado-Ordorica, M.A., E-mail: mario.salgado@novelis.com [Laboratoire de Simulation des Materiaux LSMX, Ecole Polytechnique Federale de Lausanne, Station 12, 1015 Lausanne (Switzerland); Burdet, P.; Cantoni, M. [Centre Interdisciplinaire de Microscopie Electronique CIME, Ecole Polytechnique Federale de Lausanne, Station 12, 1015 Lausanne (Switzerland); Rappaz, M. [Laboratoire de Simulation des Materiaux LSMX, Ecole Polytechnique Federale de Lausanne, Station 12, 1015 Lausanne (Switzerland)

    2011-08-15

    The favorable growth kinetics of twinned dendrites can be explained by their complex morphology, multiple side branching mechanisms, growth undercooling and tip morphology. Three models were proposed for the twinned dendrite tip shape: (i) a grooved tip satisfying the Smith condition at the triple line; (ii) a doublon , i.e. a double-tip dendrite that grows with a narrow and deep liquid channel in its center; and (iii) a pointed (or edgy) tip, with consideration of the solid-liquid interfacial energy anisotropy. In the first part of this work, phase field simulations of half a twinned dendrite with an appropriate boundary condition to reproduce the Smith condition supported the doublon conjecture, with a narrow liquid channel ending its solidification with the formation of small liquid droplets. In this part, experimental observations of twinned dendrite tips reveal the presence of a small, but well-defined, groove, thus definitely eliminating the edged tip hypothesis. Focused ion beam nanotomography and energy-dispersive spectroscopy chemical analysis in a transmission electron microscope reveal the existence of a positive solute gradient in a region localized within 2 {mu}m around the twin plane. In Al-Zn specimens, small particles aligned within the twin plane further support the doublon conjecture and the predicted formation of small liquid droplets below the doublon root.

  8. [Effective communication with talkative patients: 10 tips].

    Science.gov (United States)

    Giroldi, Esther; Veldhuijzen, Wemke; Bareman, Frits; Bueving, Herman; van der Weijden, Trudy; van der Vleuten, Cees; Muris, Jean

    2016-01-01

    Consultations with talkative patients present a challenge to doctors. It is difficult to gather all the necessary information within the available time, without damaging the doctor-patient relationship. Based on the listed existing literature and doctors' experiences, we present ten tips for gathering information from talkative patients in an effective manner whilst maintaining a good therapeutic alliance. In consultations with talkative patients, it is important to explore the cause of patients' talkativeness and to adapt one's communication approach accordingly.- Familiar communication strategies such as 'summarizing' can still be applied. When taking this route, a more directive communication approach--e.g. by means of a 'closed-ended summary'--can prevent the patient interrupting the doctor or departing from his subject. There are strategies aimed at avoiding a damaging effect to the doctor-patient relationship when applying this approach: don't be overly directive, make the patient co-responsible for efficient time management in the consultation, and make use of empathic interrupting and humour.

  9. Twelve tips for facilitating successful teleconferences.

    Science.gov (United States)

    Chou, Calvin L; Promes, Susan B; Souza, Kevin H; Topp, Kimberly S; O'Sullivan, Patricia S

    2012-01-01

    The work of medical education is increasingly collaborative across geographical sites, sometimes spanning international borders. The success of projects depends more strongly on how meetings are led and run than variables about the task itself; therefore, excellent communication using teleconferencing technology is required. However, we found no medical literature to assist with developing best practices in telecommunication. Using the organization and management literature, which has examined the use of telecommunication in optimizing work outcomes, we provide a guide for initiating and facilitating teleconferences. We used Tuckman's framework for group development as a means of organizing guidelines that address practical issues in approaching communication on teleconferences and discuss important aspects of forming work groups using telecommunication, setting ground rules and norms, addressing conflict, and enhancing accountability and outcomes. We identified 12 tips for optimal teleconferencing and divided them into phases of formation, setting ground rules, managing conflict, and enhancing group performance. Successful work on teleconferences requires excellent attention to the group process, especially since full engagement by participants is not always assured.

  10. Central venous line complications and tip detection

    Directory of Open Access Journals (Sweden)

    Ameneh Rezaee Gheshlaghi

    2015-06-01

    Full Text Available Central venous line is one of a creative instrument that saves human’s life in critical medical situation. Central venous line access is frequently involved in the disease management. It is used for rapid fluid therapy, transvenous pacemakers, infusion of some medications, hemodialysis or plasmapheresis and etc. Most of the emergency departments have some staffs that are trained for central venous line insertion but related complications occur during central venous line placement.Central venous line might have some complications and complication follow-up should be considered. Thromboembolism and infection are two important medical complications. Arterial puncture, hematoma, pneumothorax and hemothorax are mechanical Central venous line complications. Chest X-ray and some other techniques should be used for detecting these complications.Central venous line tip misplace is a considerable problem for emergency department staffs, previously chest X-ray has been used for central venous line misplace detection. In some recent studies, contrast-enhanced ultrasonography and intravascular electrocardiography have been used for central venous line misplace.

  11. A tipping point in parapatric speciation.

    Science.gov (United States)

    Yamaguchi, Ryo; Iwasa, Yoh

    2017-05-21

    More than two loci are involved in reproductive isolation in most cases of putative recent speciation. We study the speciation between two geographically isolated populations connected by infrequent migration, in which incompatibility is controlled by quantitative loci. Incompatibility genetic distance is defined as the fraction of compatibility controlling loci that are different between individuals. Speciation is established when genetic distance reaches a threshold level in spite of occasional migration and subsequent hybridization that reduce genetic distance. With stochastic analysis, we investigate how the time to speciation depends on the manner in which the magnitude of incompatibility increases with genetic distance. Results are: (1) The time to speciation is short if the migration rate is smaller than the mutation rate, or if intermediate levels of genetic distance cause mild incompatibility, making migrants less effective in reducing genetic distance. (2) Genetic distance may fluctuate around a positive quasi-equilibrium level for a long time, and suddenly show a quick passage to speciation when it goes beyond a "tipping point." Notably a gradual increase in incompatibility can result in a sudden and rapid formation of a new species. (3) Speciation becomes very slow if incompatibility is effective for individuals differing at only one locus. These findings provide testable predictions on reproductive traits controlled by specific incompatibility accumulation forms that facilitate the speciation process. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Tipping toward sustainability: emerging pathways of transformation.

    Science.gov (United States)

    Westley, Frances; Olsson, Per; Folke, Carl; Homer-Dixon, Thomas; Vredenburg, Harrie; Loorbach, Derk; Thompson, John; Nilsson, Måns; Lambin, Eric; Sendzimir, Jan; Banerjee, Banny; Galaz, Victor; van der Leeuw, Sander

    2011-11-01

    This article explores the links between agency, institutions, and innovation in navigating shifts and large-scale transformations toward global sustainability. Our central question is whether social and technical innovations can reverse the trends that are challenging critical thresholds and creating tipping points in the earth system, and if not, what conditions are necessary to escape the current lock-in. Large-scale transformations in information technology, nano- and biotechnology, and new energy systems have the potential to significantly improve our lives; but if, in framing them, our globalized society fails to consider the capacity of the biosphere, there is a risk that unsustainable development pathways may be reinforced. Current institutional arrangements, including the lack of incentives for the private sector to innovate for sustainability, and the lags inherent in the path dependent nature of innovation, contribute to lock-in, as does our incapacity to easily grasp the interactions implicit in complex problems, referred to here as the ingenuity gap. Nonetheless, promising social and technical innovations with potential to change unsustainable trajectories need to be nurtured and connected to broad institutional resources and responses. In parallel, institutional entrepreneurs can work to reduce the resilience of dominant institutional systems and position viable shadow alternatives and niche regimes.

  13. Nasal tip projection and facial attractiveness.

    Science.gov (United States)

    Devcic, Zlatko; Rayikanti, Benjamin A; Hevia, Jesse P; Popenko, Natalie A; Karimi, Koohyar; Wong, Brian J F

    2011-07-01

    Six nasal tip projection (NTP) ratios from Goode, Simons, Baum, Powell, and Crumley guide clinical and academic practice on quantifying NTP, but none have been empirically correlated with facial attractiveness. This study's objectives were to determine: 1) if there is a correlation between these ratios and facial attractiveness; and 2) which of the six ratios has the greatest linkage to overall facial attractiveness. Basic research study. There were 300 digital portraits of women (ages 18-25 years) randomly paired and morphed to create 300 synthetic lateral facial images rated by 78 raters in the community. NTP ratios were measured in each portrait. None of the ratios correlated with facial attractiveness. For the Baum, Powell, and Simons ratio, facial attractiveness increased as NTP deviated 1 and 2 standard deviations from the ideal, whereas facial attractiveness decreased as NTP deviated from the Goode and Crumley ideal ratios. The most attractive faces had NTP ratios consistent with previous expert opinion findings. To our knowledge, this is the first study to empirically correlate these six landmark NTP ratios with facial attractiveness. Although there was no correlation with any of the six ratios, the ideal ratios proposed by Goode and Crumley impacted facial aesthetics the most. Although the ideal ratios are useful in establishing rhinoplasty guidelines, they should only be used as a part of the management in achieving an aesthetic face on the whole, as they may not be robust enough to correlate with overall facial attractiveness. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.

  14. Radiofrequency Ablation with an Enhanced-Irrigation Flexible-Tip Catheter versus a Standard-Irrigation Rigid-Tip Catheter.

    Science.gov (United States)

    Hussein, Ayman A; Oberti, Carlos; Wazni, Oussama M; Hegrenes, Jami A; Sral, John A; Lopez, John; Kowalewski, William; Kattar, Jacqueline; Kanj, Mohamed; Lindsay, Bruce; Saliba, Walid

    2015-10-01

    The flexible-tip irrigated ablation catheter Cool Flex™ (St. Jude Medical, St. Paul, MN, USA) was introduced to enhance cooling of the catheter-tissue interface and to conform to endocardial surface with better contact. Little is known about the performance of such catheter design compared to the widely used rigid-tip catheters. In a thigh muscle preparation, ablation using the flexible-tip and rigid-tip catheters was performed in seven pigs across a range of ablation settings and catheter orientation. Postprocedure, the thigh muscle was stained with 2,3,5-triphenyltetrazolium-chloride injected into the femoral artery. The muscle was excised, fixed with formalin, and examined grossly. A total of 196 lesions (95 flexible tip, 101 rigid tip) were evaluated. The flexible-tip catheter was associated with enhanced cooling of catheter-tissue interface (31.1 ± 3.3°C vs 36.3 ± 3.7°C, P = 0.0001) in both perpendicular and nonperpendicular catheter orientations. This allowed more energy delivery (37.3 ± 8.9 W vs 33.7 ± 8.1 W, P = 0.004) to targeted tissue and resulted in larger lesions (median 194.7 [interquartile range: 113.1-333.8] mm(3) vs 170.9 [88.7-261.6] mm(3) , P = 0.03) than the rigid-tip catheter with larger maximum diameter (11.1 ± 2.6 mm vs 10.3 ± 2.1 mm, P = 0.03) and larger diameter at tissue surface (10.3 ± 2.4 mm vs 9.6 ± 1.7 mm, P = 0.01). Catheter orientation during ablation affected the efficiency of rigid-tip but not the flexible-tip catheter. The use of the flexible-tip catheter was associated with significantly less char formation on tissue (none vs 5.1% with rigid tip, P = 0.009). The Cool Flex™ catheter performed better than a rigid-tip catheter with enhanced cooling, larger ablation lesions, and no charring of targeted tissue. © 2015 Wiley Periodicals, Inc.

  15. Multinationals and plant survival

    DEFF Research Database (Denmark)

    Bandick, Roger

    2010-01-01

    The aim of this paper is twofold: first, to investigate how different ownership structures affect plant survival, and second, to analyze how the presence of foreign multinational enterprises (MNEs) affects domestic plants’ survival. Using a unique and detailed data set on the Swedish manufacturing...... sector, I am able to separate plants into those owned by foreign MNEs, domestic MNEs, exporting non-MNEs, and purely domestic firms. In line with previous findings, the result, when conditioned on other factors affecting survival, shows that foreign MNE plants have lower survival rates than non......-MNE plants. However, separating the non-MNEs into exporters and non-exporters, the result shows that foreign MNE plants have higher survival rates than non-exporting non-MNEs, while the survival rates of foreign MNE plants and exporting non-MNE plants do not seem to differ. Moreover, the simple non...

  16. Twelve tips on teaching and learning humanism in medical education.

    Science.gov (United States)

    Cohen, Libby Gordon; Sherif, Youmna Ashraf

    2014-08-01

    The teaching of humanistic values is recognized as an essential component of medical education and continuing professional development of physicians. The application of humanistic values in medical care can benefit medical students, clinicians and patients. This article presents 12 tips on fostering humanistic values in medical education. The authors reviewed the literature and present 12 practical tips that are relevant to contemporary practices. The tips can be used in teaching and sustaining humanistic values in medical education. Humanistic values can be incorporated in formal preclinical environments, the transition into clinical settings, medical curricula and clinical clerkships. Additionally, steps can be taken so that medical educators and institutions promote and sustain humanistic values.

  17. Tip tilt corection for astronomical telescopes using adaptive control

    Energy Technology Data Exchange (ETDEWEB)

    Watson, J.

    1997-04-17

    The greatest hindrance to modern astronomy is the effect of the Earth`s atmosphere on incoming light. The fundamental, or lowest mode of disturbance is tip and tilt.. This mode causes the focused image of a distant point source to move about in a plane (X-Y motion) as viewed form a telescope objective. Tip-tilt correction systems can be used to correct for these disturbances in real time. We propose a novel application of adaptive control to address some unique problems inherent with tip-tilt correction systems for astronomical telescopes.

  18. Factors Influencing Customers' Tipping Behaviour in Restaurants in Luzern

    OpenAIRE

    Jessica, Jessica

    2015-01-01

    Food and food service that are widely known today have always played an important role in Europe. Cultural differences, also high quality and variety of meals provided in Europe have become the main reason why there are so many restaurants as they are now, including in Luzern. Thus, resulting in a culture of dining out, which cannot be separated from the norm of tipping. Since the 18th century, tipping has become a custom in Europe. People give tips to express their gratitude for the service ...

  19. Technical tips for collagenase injection treatment for Dupuytren contracture.

    Science.gov (United States)

    Meals, Roy A; Hentz, Vincent R

    2014-06-01

    We describe technical tips for injecting collagenase into Dupuytren cords based on experience acquired during the prerelease Food and Drug Administration clinical trials and with subsequent clinical practice. These tips include techniques for extracting the reconstituted enzyme efficiently from the vial, injecting the cord(s) with increased safety to the tendons, and anesthetizing the hand before manipulation. The tips are intended to supplement but by no means replace the manufacturer's prescribing information and training video. Copyright © 2014 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  20. Stress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytes.

    Directory of Open Access Journals (Sweden)

    Joseph B Fisher

    Full Text Available BACKGROUND: Tat-interactive protein 60 (Tip60 is a member of the MYST family of histone acetyltransferases. Studies using cultured cells have shown that Tip60 has various functions including DNA repair, apoptosis and cell-cycle regulation. We globally ablated the Tip60 gene (Htatip, observing that Tip60-null embryos die at the blastocyst stage (Hu et al. Dev.Dyn.238:2912;2009. Although adult heterozygous (Tip60(+/- mice reproduce normally without a haploinsufficient phenotype, stress caused by Myc over-expression induced B-cell lymphoma in Tip60(+/- adults, suggesting that Tip60 is a tumor suppressor (Gorrini et al. Nature 448:1063;2007. These findings prompted assessment of whether Tip60, alternative splicing of which generates two predominant isoforms termed Tip60α and Tip60β, functions to suppress the cell-cycle in adult cardiomyocytes. METHODOLOGY/PRINCIPAL FINDINGS: Western blotting revealed that Tip60α is the predominant Tip60 isoprotein in the embryonic heart, transitioning at neonatal stages to Tip60β, which is the only isoprotein in the adult heart wherein it is highly enriched. Over-expression of Tip60β, but not Tip60α, inhibited cell proliferation in NIH3T3 cells; and, Tip60-haploinsufficient cultured neonatal cardiomyocytes exhibited increased cell-cycle activity. To address whether Tip60β suppresses the cardiomyocyte cell-cycle in the adult heart, hypertrophic stress was induced in Tip60(+/+ and Tip(+/- littermates via two methods, Myc over-expression and aortic banding. Based on immunostaining cell-cycle markers and western blotting cyclin D, stress increased cardiomyocyte cell-cycle mobilization in Tip60(+/- hearts, in comparison with Tip60(+/+ littermates. Aortic-banded Tip60(+/- hearts also exhibited significantly decreased apoptosis. CONCLUSIONS/SIGNIFICANCE: These findings provide evidence that Tip60 may function in a tumor suppressor pathway(s to maintain adult cardiomyocytes in replicative senescence.

  1. Position of the mental foramen in a Korean population: a clinical and radiographic study.

    Science.gov (United States)

    Kim, In-Soo; Kim, Su-Gwan; Kim, Young-Kyun; Kim, Jae-Duk

    2006-12-01

    The purpose of this study was to improve the treatment methods for the mental foramen by comparing the directly measured values with the radiographic measured values. One hundred and twelve mental foramina (72 males, 40 females) that were exposed during the operation were examined. The patients' age ranged from 12 to 69 years, with a mean age of 41.8 years. All patients had fully erupted lower premolars. The horizontal and vertical locations were evaluated with both direct and radiographic measurements. In 72 patients (64.3%), the mental foramen was below the second premolar. In 26.8%, it was between the first and second premolar, and in 8.9%, it was below the first premolar. By radiographic readings,most of the mental foramina were found to be below the second premolar (62.5%). The average distance between the cusp tip and the superior border of the mental foramen by direct measurement was 23.42 mm and 25.69 mm in the panoramic view. The mean distance between the superior border of the mental foramen and the bottom of the mandible was 14.33 mm by direct measurement and 16.52 mm by radiographic measurements. It is important to know the position of the mental foramen for the placement of osseointegrated implants in the mandibular premolar region. The position of the mental foramen of Koreans is closer to the cusp tips of lower premolars than Westerners.

  2. Tipping point analysis of seismological data

    Science.gov (United States)

    Livina, Valerie N.; Tolkova, Elena

    2014-05-01

    We apply the tipping point toolbox [1-7] to study sensor data of pressure variations and vertical velocity of the sea floor after two seismic events: 21 October 2010, M6.9, D10km (California) and 11 March 2011, M9.0, D30km (Japan). One type of datasets was measured by nano-resolution pressure sensor [8], while the other, for comparison, by a co-located ocean bottom seismometer. Both sensors registered the seismic wave, and we investigated the early warning and detection signals of the wave arrival for possible application with a remote and cabled tsunami warning detector network (NOAA DART system and Japan Trench Tsunami Observation System). We study the early warning and detection signals of the wave arrival using methodology that combines degenerate fingerprinting and potential analysis techniques for anticipation, detection and forecast of tipping points in a dynamical system. Degenerate fingerprinting indicator is a dynamically derived lag-1 autocorrelation, ACF (or, alternatively, short-range scaling exponent of Detrended Fluctuation Analysis, DFA [1]), which shows short-term memory in a series. When such values rise monotonically, this indicates an upcoming transition or bifurcation in a series and can be used for early warning signals analysis. The potential analysis detects a transition or bifurcation in a series at the time when it happens, which is illustrated in a special contour plot mapping the potential dynamics of the system [2-6]. The methodology has been extensively tested on artificial data and on various geophysical, ecological and industrial sensor datasets [2-5,7], and proved to be applicable to trajectories of dynamical systems of arbitrary origin [9]. In this seismological application, we have obtained early warning signals in the described series using ACF- and DFA-indicators and detected the Rayleigh wave arrival in the potential contour plots. In the case of the event in 2010, the early warning signal starts appearing about 2 min before

  3. Tipping points in Anthropocene fluvial dynamics

    Science.gov (United States)

    Notebaert, Bastiaan; Broothaerts, Nils; Verstraeten, Gert; Berger, Jean-François; Houbrechts, Geoffrey

    2016-04-01

    the river partially maintains its braided pattern. The Amblève River in the Belgian Ardennes uplands underwent less dramatic changes. Large parts of the catchment are deforested during the last 700 years, leading to an increase in floodplain sedimentation. Despite this major sediment pulse, change in floodplain morphology remained limited to an increase in bank height. We argue that a combination of floodplain and channel morphology, the fine texture of supplied sediment and the high stream power of channel forming events result is a system that is less sensitive to change. Also the relative short time of impact may play a role. These three examples demonstrate the varying impact of human deforestation on floodplain geomorphology. For the Dijle and Valdaine region this lead to dramatic changes once a certain tipping point is reached. In contrast the Amblève river is more resilient to human impact due to its specific morphological setting. The morphology of the catchments and the nature of supplied sediments plays a major role in the sensitivity of fluvial systems to environmental impact. Once the tipping points are reached, it is difficult for the river to revert to its original state and floodplains remain highly impacted.

  4. Micropropagation of an elite F1 watermelon (Citrullus lanatus hybrid from the shoot tip of field grown plants

    Directory of Open Access Journals (Sweden)

    Mohammad Khalekuzzaman

    2012-06-01

    Full Text Available The aim of this work was to develop a protocol for rapid micropropagation of an elite F1 hybrid watermelon cultivar using shoot tip of field-grown plants. Maximum frequency (73% of shoot tip showed growth response in MS medium supplemented with 5 mg l-1 benzyl adenine (BA and 0.1 mg l-1 indole-3 acetic acid (IAA. Upon transfer to cytokinin-enriched medium, the cultures produced multiple shoots and 2.0 mg l-1 BA was optimum in this respect. Addition of gibberellic acid (GA3 in the multiplication medium resulted in better growth of shoots. Rooting rate was 100% when shoots were obtained from second subculture were cultured in medium with 1.0 mg l-1 indole-3 butyric acid (IBA. The shoots produced more roots with increasing number of subcultures. About 72% of the regenerated plantlets acclimatized successfully and survived in the soil condition.

  5. Top Ten Tips for Dealing with a Picky Eater

    Science.gov (United States)

    ... Preschoolers Infographic How to Make a Healthy Home Dietary Recommendations for Healthy Children Top 10 Tips to Help Children Develop Healthy Habits Fruit and Veggie Toolkit for Kids Healthy Foods ...

  6. Tips for More Productive Parent-Teacher Conferences.

    Science.gov (United States)

    Knox, Laura; Candelaria, Cynthia

    1987-01-01

    Tips to break the tension and make parent-teacher conferences productive are offered. A reproducible page with suggestions for parents entitled "How To Get the Most Out of Parent-Teacher Conferences" is included. (MT)

  7. DEFORMATION INFLUENCE ON A LIFETIME OF WELDING ELECTRODE TIPS

    Directory of Open Access Journals (Sweden)

    Ján Viňáš

    2009-02-01

    Full Text Available The contribution deals with the influence of welding electrode tips deformation on their lifetime. The influence of material properties, production technology and the intensity of welding electrodes load on their lifetime are presented. The electrode tips of the most used type of CuCr1Zr alloy of three basic standard shapes before and after the process of welding are evaluated. The process of welding is realized with low, middle and maximum welding parameters on programmable pneumatic spot welding machine VTS BPK 20. The influence of welding parameters on chosen material characteristics of welding tips is observed. Through the use of upsetting test, dependency of forming strength and deformation of material on used technology of welding tip production is observed.

  8. Rheumatoid Arthritis Pain: Tips for Protecting Your Joints

    Science.gov (United States)

    Rheumatoid arthritis pain: Tips for protecting your joints Use these joint protection techniques to help you stay in control of your rheumatoid arthritis pain. By Mayo Clinic Staff Joint protection is ...

  9. Tips for Coping: The Music Educator and Stress.

    Science.gov (United States)

    Radocy, Rudolf E.; Heller, George N.

    1982-01-01

    Discusses sources of stress for music teachers and offers tips for coping with it. Relaxation exercises, physical exercise, and a change of environment are recommended. Teachers should realistically assess their abilities and career prospects. (AM)

  10. Tax Tips for Forest Landowners for the 2013 Tax Year

    Science.gov (United States)

    Linda Wang; John Greene

    2013-01-01

    This annual bulletin provides federal income tax reporting tips to assist forest landowners and their advisers in filing their 2013 income tax returns. The information presented here is current as of Sept. 15, 2013.

  11. Surface- and tip-enhanced raman spectroscopy in catalysis

    NARCIS (Netherlands)

    Hartman, Thomas; Wondergem, Caterina S.; Kumar, Naresh; van den Berg, Albert; Weckhuysen, Bert M.

    2016-01-01

    Surface- and tip-enhanced Raman spectroscopy (SERS and TERS) techniques exhibit highly localized chemical sensitivity, making them ideal for studying chemical reactions, including processes at catalytic surfaces. Catalyst structures, adsorbates, and reaction intermediates can be observed in low

  12. Surface- and Tip-Enhanced Raman Spectroscopy in Catalysis

    NARCIS (Netherlands)

    Hartman, Thomas|info:eu-repo/dai/nl/412640635; Wondergem, Caterina S.; Kumar, Naresh; van den Berg, Albert; Weckhuysen, Bert M.|info:eu-repo/dai/nl/285484397

    2016-01-01

    Surface- and tip-enhanced Raman spectroscopy (SERS and TERS) techniques exhibit highly localized chemical sensitivity, making them ideal for studying chemical reactions, including processes at catalytic surfaces. Catalyst structures, adsorbates, and reaction intermediates can be observed in low

  13. Children with Chronic Kidney Disease: Tips for Parents

    Science.gov (United States)

    ... Donate A to Z Health Guide Children With Chronic Kidney Disease: Tips for Parents Print Email If your child has been diagnosed with chronic kidney disease, you are no doubt feeling distressed and bewildered. ...

  14. Sharp tipped plastic hollow microneedle array by microinjection moulding

    Science.gov (United States)

    Yung, K. L.; Xu, Yan; Kang, Chunlei; Liu, H.; Tam, K. F.; Ko, S. M.; Kwan, F. Y.; Lee, Thomas M. H.

    2012-01-01

    A method of producing sharp tipped plastic hollow microneedle arrays using microinjection moulding is presented in this paper. Unlike traditional approaches, three mould inserts were used to create the sharp tips of the microneedles. Mould inserts with low surface roughness were fabricated using a picosecond laser machine. Sharp tipped plastic hollow microneedles 500 µm in height were fabricated using a microinjection moulding machine developed by the authors’ group. In addition, the strength of the microneedle was studied by simulation and penetration experiments. Results show that the microneedles can penetrate into skin, delivering liquid successfully without any breakage or severe deformation. Techniques presented in this paper can be used to fabricate sharp tipped plastic hollow microneedle arrays massively with low cost.

  15. Tips to Make Fast Food Friendlier for Kids

    Science.gov (United States)

    ... Workplace Food and Beverage Toolkit Tips to Make Fast Food Friendlier for Kids Updated:Feb 6,2017 Finding it hard to feed your children nutritious meals between all your daily activities? While ...

  16. Coral Reef Resilience, Tipping Points and the Strength of Herbivory

    National Research Council Canada - National Science Library

    Sally J Holbrook; Russell J Schmitt; Thomas C Adam; Andrew J Brooks

    2016-01-01

    .... Assessment of where any coral reef ecosystem lies in relation to the coral-to-macroalgae tipping point is fundamental to understanding resilience properties, forecasting state shifts, and developing...

  17. TIPS to reduce Pressure Decreasess rebleed and Death (Monescillo ...

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. TIPS to reduce Pressure Decreasess rebleed and Death (Monescillo A, Oct 2004, Hepatology). 116 Bleeders. Liver Pressure > 20 mm Hg - 52 Patients (high risk)

  18. Energy Efficiency and Renewable Energy in SIPs and TIPs

    Science.gov (United States)

    Tools and guides to encourage state, tribal and local agencies to consider incorporating Energy Efficiency (EE) and Renewable Energy (RE) policies and programs in their State and Tribal Implementation Plans (SIPs/TIPs).

  19. Salmonella Is a Sneaky Germ: Seven Tips for Safer Eating

    Science.gov (United States)

    ... Past Emails Salmonella is a Sneaky Germ: Seven Tips for Safer Eating Recommend on Facebook Tweet Share ... file Microsoft PowerPoint file Microsoft Word file Microsoft Excel file Audio/Video file Apple Quicktime file RealPlayer ...

  20. Tips for Starting Yoga in Adults with Migraines

    Science.gov (United States)

    ... library . Read More Read More › Migraine and Your Marriage heather February 14, 2018 Tips for navigating migraine ... Migraine Migraine with Brainstem Aura (Basilar Type Migraine) Effects of Exercise on Headaches and Migraines When Should ...

  1. Crack Tip Flipping Under Mode I/III Tearing

    DEFF Research Database (Denmark)

    Felter, Christian Lotz; Specht Jensen, Lasse; Nielsen, Kim Lau

    Crack tip flipping, where the fracture surface alternates from side to side in 45° shear bands, seems to be an overlooked propagation mode in Mode I sheet tearing often disregarded as  “transitional” or tied to randomness in the material. In fact, such observations rarely make it to the literature....... However, crack tip flipping is a true propagation mode, but unlike those already established: i) it never settles in a steady-state as the near tip stress/strain field continuously change, and ii) the mechanism governing failure evolves behind the leading crack tip. Recent research has revealed new...... insight into this intriguing behavior of a crack propagating by the void nucleation and growth mechanism, and the work presented compiles both published and unpublished experimental and numerical findings. E.g. in a recent attempt to gain control of the flipping crack a slight Mode III was imposed...

  2. Assisted crack tip flipping under Mode I thin sheet tearing

    DEFF Research Database (Denmark)

    Felter, Christian Lotz; Nielsen, Kim Lau

    2017-01-01

    Crack tip flipping, where the fracture surface alternates from side to side in roughly 45° shear bands, seems to be an overlooked propagation mode in Mode I thin sheet tearing. In fact, observations of crack tip flipping is rarely found in the literature. Unlike the already established modes...... such as slanting, cup-cone (rooftop), or cup-cup (bathtub) the flipping crack never settles in a steady-state as the near tip stress/strain field continuously change when the flip successively initiates and develops shear-lips. A recent experimental investigation has revealed new insight by exploiting 3D X......-ray tomography scanning of a developing crack tip flip. But, it remains to be understood what makes the crack flip systematically, what sets the flipping frequency, and under which material conditions this mode occurs. The present study aims at investigating the idea that a slight out-of-plane action (Mode III...

  3. Modelling tipping-point phenomena of scientific coauthorship networks

    CERN Document Server

    Xie, Zheng; Yi, Dongyun; Zhenzheng, Ouyang; Li, Jianping

    2016-01-01

    In a range of scientific coauthorship networks, tipping points are detected in degree distributions, correlations between degrees and local clustering coefficients, etc. The existence of those tipping points could be treated as a result of the diversity of collaboration behaviours in scientific field. A growing geometric hypergraph built on a cluster of concentric circles is proposed to model two typical collaboration behaviours, namely the behaviour of leaders and that of other members in research teams. The model successfully predicts the tipping points, as well as many common features of coauthorship networks. For example, it realizes a process of deriving the complex scale-free property from the simple yes/no experiments. Moreover, it gives a reasonable explanation for the emergence of tipping points by the difference of collaboration behaviours between leaders and other members, which emerges in the evolution of research teams. The evolution synthetically addresses typical factors of generating collabora...

  4. Tipping Points? Curvilinear Associations between Activity Level and Mental Development in Toddlers

    Science.gov (United States)

    Flom, Megan; Cohen, Madeleine; Saudino, Kimberly J.

    2017-01-01

    The Theory of Optimal Stimulation (Zentall & Zentall, "Psychological Bulletin," 94, 1983, 446) posits that the relation between activity level (AL) and cognitive performance follows an inverted U shape where midrange AL predicts better cognitive performance than AL at the extremes. We explored this by fitting linear and quadratic…

  5. Neural Rating Regression with Abstractive Tips Generation for Recommendation

    OpenAIRE

    Li, Piji; Wang, Zihao; Ren, Zhaochun; Bing, Lidong; Lam, Wai

    2017-01-01

    Recently, some E-commerce sites launch a new interaction box called Tips on their mobile apps. Users can express their experience and feelings or provide suggestions using short texts typically several words or one sentence. In essence, writing some tips and giving a numerical rating are two facets of a user's product assessment action, expressing the user experience and feelings. Jointly modeling these two facets is helpful for designing a better recommendation system. While some existing mo...

  6. Trade and Industrial Policy Strategies (TIPS) : financement de base ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    TIPS a revu et élargi son programme qui comporte désormais six grands champs d'études, à savoir le commerce, l'intégration économique régionale en Afrique, le développement industriel, le développement rural, les inégalités et la marginalisation économique et, enfin, le développement durable. TIPS organisera ...

  7. Coral Reef Resilience, Tipping Points and the Strength of Herbivory

    OpenAIRE

    Holbrook, Sally J.; Schmitt, Russell J.; Adam, Thomas C.; Brooks, Andrew J.

    2016-01-01

    Coral reefs increasingly are undergoing transitions from coral to macroalgal dominance. Although the functional roles of reef herbivores in controlling algae are becoming better understood, identifying possible tipping points in the herbivory-macroalgae relationships has remained a challenge. Assessment of where any coral reef ecosystem lies in relation to the coral-to-macroalgae tipping point is fundamental to understanding resilience properties, forecasting state shifts, and developing effe...

  8. Tip Vortex Index (TVI) Technique for Inboard Propeller Noise Estimation

    OpenAIRE

    Sezen, Savaş; Dogrul, Ali; Bal, Şakir

    2018-01-01

    Cavitating marine propeller is one of the most dominant noise sources inmarine vessels.  The aim of this study isto examine the cavitating propeller noise induced by tip vortices for twinscrew passenger vessels. To determine the noise level inboard, tip vortex index(TVI) technique has been used. This technique is an approximate method based onnumerical and experimental data. In this study, it is aimed to predict theunderwater noise of a marine propeller by applying TVI technique for ...

  9. Trade and Industrial Policy Strategies (TIPS) - phase III | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Trade and Industrial Policy Strategies (TIPS) - phase III. Établi en 1996, le réseau de chercheurs de l'organisme Trade and Industrial Policy Strategies (TIPS) souhaite fournir au gouvernement de l'Afrique du Sud, à la société civile et à la région des conseils impartiaux en matière de politiques économiques, ...

  10. Pre-Liver Transplant: Tips Versus Distal Splenorenal Shunt

    Directory of Open Access Journals (Sweden)

    Thomas W. Faust

    1997-01-01

    Full Text Available Recurrent variceal bleeding in liver transplant candidates with end-stage liver disease can complicate or even prohibit a subsequent transplant procedure (OLT. Endoscopic sclero-therapy and medical therapy are considered as first-line management with surgical shunts reserved for refractory situations. Surgical shunts can be associated with a high mortality in this population and may complicate subsequent OLT. The transjugular intrahepatic portosystemic shunt (TIPS has been recommended in these patients as a bridge to OLT. This is a new modality that has not been compared with previously established therapies such as the distal splenorenal shunt (DSRS. In this study we report our experience with 35 liver transplant recipients who had a previous TIPS (18 patients or DSRS (17 patients for variceal bleeding. The TIPS group had a significantly larger proportion of critically ill and Child-Pugh C patients. Mean operating time was more prolonged in the DSRS group (P=0.014 but transfusion requirements were similar. Intraoperative portal vein blood flow measurements averaged 2132±725 ml/min in the TIPS group compared with 1120±351ml/min in the DSRS group (P<0.001. Arterial flows were similar. Mean ICU and hospital stays were similar. There were 3 hospital mortalities in the DSRS group and none in the TIPS group (P=0.1. We conclude that TIPS is a valuable tool in the management of recurrent variceal bleeding prior to liver transplantation. Intra0Perative hemodynamic measurements suggest a theoretical advantage with TIPS. In a group of patients with advanced liver disease we report an outcome that is similar to patients treated with DSRS prior to liver transplantation. The role of TIPS in the treatment of nontransplant candidates remains to be clarified.

  11. High Speed Imaging of Cavitation around Dental Ultrasonic Scaler Tips.

    Science.gov (United States)

    Vyas, Nina; Pecheva, Emilia; Dehghani, Hamid; Sammons, Rachel L; Wang, Qianxi X; Leppinen, David M; Walmsley, A Damien

    2016-01-01

    Cavitation occurs around dental ultrasonic scalers, which are used clinically for removing dental biofilm and calculus. However it is not known if this contributes to the cleaning process. Characterisation of the cavitation around ultrasonic scalers will assist in assessing its contribution and in developing new clinical devices for removing biofilm with cavitation. The aim is to use high speed camera imaging to quantify cavitation patterns around an ultrasonic scaler. A Satelec ultrasonic scaler operating at 29 kHz with three different shaped tips has been studied at medium and high operating power using high speed imaging at 15,000, 90,000 and 250,000 frames per second. The tip displacement has been recorded using scanning laser vibrometry. Cavitation occurs at the free end of the tip and increases with power while the area and width of the cavitation cloud varies for different shaped tips. The cavitation starts at the antinodes, with little or no cavitation at the node. High speed image sequences combined with scanning laser vibrometry show individual microbubbles imploding and bubble clouds lifting and moving away from the ultrasonic scaler tip, with larger tip displacement causing more cavitation.

  12. Can We Avoid the Permafrost Carbon Tipping Point?

    Science.gov (United States)

    Schaefer, K. M.; Zhang, T.; Bruhwiler, L.; Barrett, A. P.; Li, Z.

    2011-12-01

    If we reduce fossil fuel emissions and slow the Arctic warming rate, can we delay or even avoid the permafrost carbon tipping point? Permafrost currently contains about 1466 Gt of carbon frozen during or since the last ice age. The permafrost carbon tipping point occurs when the release of carbon from thawing permafrost overpowers enhanced uptake due to warmer temperatures. The tipping point indicates when the Arctic irreversibly changes from a carbon sink to a source relative to the atmosphere and marks the start of the Permafrost Carbon Feedback. The tipping point is irreversible because once the carbon thaws and decays into the atmosphere, there is no way to put the carbon back into the permafrost. Projections based on the A1B IPCC scenario indicate that the PCF tipping point will occur between 2020 and 2030, with a total of 190±64 Gt of carbon released into the atmosphere by 2300. We ran a series of model projections out to 2300 based on the A1B scenario, but capped emissions at various levels, each representing a different overall Arctic warming. We present the area of permafrost lost, the permafrost carbon tipping point, and total permafrost carbon flux as a function of Arctic temperature increase. We show the maximum allowed Arctic temperature increase before initiating the permafrost carbon feedback.

  13. Aesthetic rhinoplasty of the Asian nasal tip: a brief review.

    Science.gov (United States)

    Mao, Guang-Yu; Yang, Song-Lin; Zheng, Jiang-Hong; Liu, Qing-Yang

    2008-07-01

    Tip surgery, the most important part of the rhinoplasty procedure, has entered a new era in the past few decades. Various treatment protocols have been attempted. To date, however, opinions on the management of the Asian tip have not been solidified. To generalize and provide appropriate guidelines for the treatment of typical Asian tips, an English literature search from 1977 to March 2007 was conducted. Finally, a total of 26 papers were selected for review. The full text of each paper was read carefully, and data were extracted. Then all extracted information was imported into Microsoft Excel. Nine articles treating 11 groups of patients described the suitable techniques for Asian nasal tips, with 81.8% of the groups advocating that the protocol include a grafting technique, 64% reporting use of the grafting technique alone, and 9% applying cartilage reduction and a suturing technique. Of the 11 (18%) groups, 2 attempted more than one technique. Because of the Asian nasal tip's innate qualities, success with nasal tip plasty for Asians depends on the combined application of appropriate suturing, grafting, and defatting, with grafting techniques contributing the most.

  14. Rise of the zombie institution, the failure of mental health nursing leadership, and mental health nursing as a zombie category.

    Science.gov (United States)

    Lakeman, Richard; Molloy, Luke

    2017-11-28

    In this paper, we propose that mental health nursing has become a zombie category, at least in the Australian context. Mental health nursing is a concept that has lost any real explanatory or conceptual power, yet nevertheless persists in public discourse and the collective imagination. In recent decades, powerful forces have contributed to the zombification of the mental health nursing workforce and the academy. An increase in medical hegemony, the ascendancy of allied health in mental health service provision, the need for uncritical and servile workers, protocol-driven work practices, and a failure of leadership to mobilize any substantial resistance to these trends have enabled the infection to spread. The recognition of zombification, active resistance against the forces that conspire to cause it, and the cultivation of genuine conscientious critical thought and debate offer the only hope of survival of mental health nursing as a thriving specialty. © 2017 Australian College of Mental Health Nurses Inc.

  15. Mental Retardation, Mental Illness, and Seizure Diagnosis.

    Science.gov (United States)

    Pary, Robert

    1993-01-01

    Review of psychiatric hospital discharge summaries for 247 individuals with mental retardation and psychiatric disorders found that 39 had a seizure diagnosis. The only difference between the groups with and without seizures was level of mental retardation. No differences existed concerning length of stay, transfer to state hospital, psychiatric…

  16. Inhibition: Mental Control Process or Mental Resource?

    Science.gov (United States)

    Im-Bolter, Nancie; Johnson, Janice; Ling, Daphne; Pascual-Leone, Juan

    2015-01-01

    The current study tested 2 models of inhibition in 45 children with language impairment and 45 children with normally developing language; children were aged 7 to 12 years. Of interest was whether a model of inhibition as a mental-control process (i.e., executive function) or as a mental resource would more accurately reflect the relations among…

  17. Novel fiber optic tip designs and devices for laser surgery

    Science.gov (United States)

    Hutchens, Thomas Clifton

    Fiber optic delivery of laser energy has been used for years in various types of surgical procedures in the human body. Optical energy provides several benefits over electrical or mechanical surgery, including the ability to selectively target specific tissue types while preserving others. Specialty fiber optic tips have also been introduced to further customize delivery of laser energy to the tissue. Recent evolution in lasers and miniaturization has opened up opportunities for many novel surgical techniques. Currently, ophthalmic surgeons use relatively invasive mechanical tools to dissect retinal deposits which occur in proliferative diabetic retinopathy. By using the tight focusing properties of microspheres combined with the short optical penetration depth of the Erbium:YAG laser and mid-IR fiber delivery, a precise laser scalpel can be constructed as an alternative, less invasive and more precise approach to this surgery. Chains of microspheres may allow for a self limiting ablation depth of approximately 10 microm based on the defocusing of paraxial rays. The microsphere laser scalpel may also be integrated with other surgical instruments to reduce the total number of handpieces for the surgeon. In current clinical laser lithotripsy procedures, poor input coupling of the Holmium:YAG laser energy frequently damages and requires discarding of the optical fiber. However, recent stone ablation studies with the Thulium fiber laser have provided comparable results to the Ho:YAG laser. The improved spatial beam profile of the Thulium fiber laser can also be efficiently coupled into a fiber approximately one third the diameter and reduces the risk of damaging the fiber input. For this reason, the trunk optical fiber minus the distal fiber tip can be preserved between procedures. The distal fiber tip, which degrades during stone ablation, could be made detachable and disposable. A novel, low-profile, twist-locking, detachable distal fiber tip interface was designed

  18. Mental Health Screening Center

    Science.gov (United States)

    ... Releases & Announcements Public Service Announcements Partnering with DBSA Mental Health Screening Center These online screening tools are not ... you have any concerns, see your doctor or mental health professional. Depression Screening for Adult Depression Screening for ...

  19. Burden of Mental Illness

    Science.gov (United States)

    ... this? Submit What's this? Submit Button Burden of Mental Illness Recommend on Facebook Tweet Share Compartir Depression: According ... anxiety disorder, are the most common class of mental disorders present in the general population. 5 The estimated ...

  20. International Student Mental Health

    Science.gov (United States)

    Prieto-Welch, Susan L.

    2016-01-01

    This chapter describes the mental health status of international students in institutions of higher education, unique challenges these students face and their impact on mental health, and suggestions for ways to address these challenges.

  1. MENTALIZING IN YOUNG OFFENDERS

    OpenAIRE

    Möller, Clara; Falkenström, Fredrik; Holmqvist Larsson, Mattias; Holmqvist, Rolf

    2014-01-01

    In order to prevent relapse into criminality, it is important to understand what precedes criminal behavior. Two earlier studies found deficits in mentalizing ability to be related to violent and criminal actions. Mentalizing refers to the ability to make human behavior predictable and meaningful by inferring mental states (thoughts, feelings, etc.) as explaining behavior. In this study, mentalizing ability was assessed by rating 42 Adult Attachment Interviews with young male offenders with t...

  2. Children's Mental Health

    Science.gov (United States)

    ... Español (Spanish) Recommend on Facebook Tweet Share Compartir Mental health in childhood means reaching developmental and emotional milestones, ... health Articles Scientific articles and key findings Children’s Mental Health: What's New Policy Brief: Access to Mental Health ...

  3. What Is Mental Health?

    Science.gov (United States)

    ... taking care of your kids or getting to work or school Learn more about specific mental health problems and where to find help . Mental Health and Wellness Positive mental health allows people to: Realize their full ... productively Make meaningful contributions to their communities Ways ...

  4. Mental Health and African Americans

    Science.gov (United States)

    ... Minority Population Profiles > Black/African American > Mental Health Mental Health and African Americans Poverty level affects mental health ... compared to 120% of non-Hispanic whites. 1 MENTAL HEALTH STATUS Serious psychological distress among adults 18 years ...

  5. Survival Prognosis in Very Old Adults

    DEFF Research Database (Denmark)

    Thinggaard, Mikael; McGue, Matt; Jeune, Bernard

    2016-01-01

    to rise without use of hands increased the chance for men to 11.2% (95% confidence interval (CI)=7.7-14.7) and for women to 22.0% (95% CI=18.9-25.1). When combining this with a Mini-Mental State Examination (MMSE) scores from 28 to 30, the chances were 21.7% (95% CI=11.5-31.9) for men and 34.2% (95% CI=24...... performance, cognition, depression symptomatology, self-rated health, and all-cause mortality, evaluated as average remaining lifespan and chance of surviving to 100 years. RESULTS: Men aged 92 to 93 had an overall 6.0% chance of surviving to 100 years, whereas the chance for women was 11.4%. Being able...

  6. Network ties and survival

    DEFF Research Database (Denmark)

    Acheampong, George; Narteh, Bedman; Rand, John

    2017-01-01

    Poultry farming has been touted as one of the major ways by which poverty can be reduced in low-income economies like Ghana. Yet, anecdotally there is a high failure rate among these poultry farms. This current study seeks to understand the relationship between network ties and survival chances...... of small commercial poultry farms (SCPFs). We utilize data from a 2-year network survey of SCPFs in rural Ghana. The survival of these poultry farms are modelled using a lagged probit model of farms that persisted from 2014 into 2015. We find that network ties are important to the survival chances...... but this probability reduces as the number of industry ties increases but moderation with dynamic capability of the firm reverses this trend. Our findings show that not all network ties aid survival and therefore small commercial poultry farmers need to be circumspect in the network ties they cultivate and develop....

  7. Mental toughness in soccer

    DEFF Research Database (Denmark)

    Diment, Gregory Michael

    2014-01-01

    In the past decade mental toughness has been discussed as a significant factor in performance in elite sport. Few studies have explored mental toughness from a behavioral perspective, and no comprehensive lists of mental toughness behaviors have been developed. The aim of the study was to produce...... a systematic observation checklist of mental toughness behavior in professional soccer. Consistent with existing studies, the results created a systematic observation instrument containing 15 mental toughness behaviors. Practical implications include goal-setting, game analysis and self-modeling interventions...

  8. Aircraft Survivability: Rotorcraft Survivability. Summer 2010

    Science.gov (United States)

    2010-01-01

    protect those who serve to protect us?” The answer is a mixed bag. I am fortunate to have joined a group of dedicated men and women who represent this...and Service subject matter experts on rotorcraft safety and survivability to complete the study and report the results to the Joint Chiefs of...Operations and Support CDD TEMP DT DT/OT LUT IOT &E BLRIP TEMP TEMP LRIP Acquisition & LFT Strategies B C LFT&E Review Requirements Approve TEMPs

  9. Effects of increasing tip velocity on wind turbine rotor design.

    Energy Technology Data Exchange (ETDEWEB)

    Resor, Brian Ray [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Maniaci, David Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Berg, Jonathan Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Richards, Phillip William [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-05-01

    A reduction in cost of energy from wind is anticipated when maximum allowable tip velocity is allowed to increase. Rotor torque decreases as tip velocity increases and rotor size and power rating are held constant. Reduction in rotor torque yields a lighter weight gearbox, a decrease in the turbine cost, and an increase in the capacity for the turbine to deliver cost competitive electricity. The high speed rotor incurs costs attributable to rotor aero-acoustics and system loads. The increased loads of high speed rotors drive the sizing and cost of other components in the system. Rotor, drivetrain, and tower designs at 80 m/s maximum tip velocity and 100 m/s maximum tip velocity are created to quantify these effects. Component costs, annualized energy production, and cost of energy are computed for each design to quantify the change in overall cost of energy resulting from the increase in turbine tip velocity. High fidelity physics based models rather than cost and scaling models are used to perform the work. Results provide a quantitative assessment of anticipated costs and benefits for high speed rotors. Finally, important lessons regarding full system optimization of wind turbines are documented.

  10. On the nature of AFM tip metal-MoS2 contact; effect of single layer character and tip force

    Science.gov (United States)

    Kaushik, Vishakha; Varandani, Deepak; Das, Pintu; Mehta, Bodh R.

    2017-10-01

    In the present study, the nature of metal-MoS2 contacts has been investigated using conductive atomic force microscopy. The point I-V characteristics have been acquired as a function of loading force (53 nN-252 nN) for an interface formed between the atomic force microscopy (AFM) tip (Pt and Co coated) and MoS2 domains (single and multilayer). The metal-MoS2 junctions for both Co and Pt tips exhibit a rectifying nature with higher forward current for the Co tip as compared to the Pt tip for both single and multilayer samples. An interesting behavior of decreasing junction current and rectification ratio with increasing tip loading force is observed in the case of single layer MoS2. In comparison, negligible or very small change in the forward junction current is observed in the case of multilayer samples. The single layer MoS2 undergoes charge polarization in the presence of uniaxial strain exerted in the form of AFM tip loading force, resulting in current in a direction opposite to the forward current due to the migration of majority electron carriers away from the tip-MoS2 interface. Therefore, the net current which is a sum of the forward junction current and the force induced current reduces with loading force for single layer MoS2. This study emphasizes the influence of the single layer nature of MoS2 on the electrical properties of metal-MoS2 contacts, an understanding of which is important from the perspective of basic physics and its applications.

  11. Thumb Tip Defect Reconstruction Using Neurovascular Island Pedicle Flap Obtained From Long Finger.

    Science.gov (United States)

    Liu, Hongjun; Regmi, Subhash; He, Yanyan; Hou, Ruixing

    2016-10-01

    Thumb tip reconstruction has been a very challenging issue for hand surgeons. Varieties of reconstructive options have been described or modified to obtain satisfactory sensory recovery. However, none has yielded entirely satisfactory results. This study reports a retrospective review of clinical data records of patients treated with a neurovascular island pedicle flap obtained from the medial aspect of the long finger. We enrolled 15 patients (9 men and 6 women), who received neurovascular island pedicle flaps for thumb tip amputations between December 2011 and December 2015. The average size of the flap was 2.8 × 2.2 cm(2) (range 2.5 × 1.8 cm(2) to 3.5 × 2.5 cm(2)). At the final follow-up visits, static two-point discrimination, visual analogue scale, Michigan hand outcome questionnaire and return-to-work time were used to evaluate surgical outcomes. All flaps survived well. The follow-up period was 18 months. The mean static 2PD values at the reconstructed thumb tip and donor finger pulp (medial side) were 5.3 mm (range 4-8 mm) and 3.2 mm (range 3-4 mm), respectively. The average VAS scores for the aesthetic appearance of the donor site and recipient site were 9.1 (range 8-10) and 9.0 (range 8-9.5), respectively. The average Michigan Hand Outcome Questionnaire (MHOQ) score for hand function (reconstructed hand) was 8.2 (range 6-16). The average RTW time was 8.4 weeks (range 7-12 weeks). Neurovascular island pedicle flap obtained from the medial aspect of long finger is a very reliable alternative technique for thumb tip defect reconstruction. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

  12. A New Tip Correction Based on the Decambering Approach

    DEFF Research Database (Denmark)

    Sørensen, Jens Nørkær; Dag, Kaya Onur; Ramos García, Néstor

    2014-01-01

    A limitation of the standard Blade Element Momentum (BEM) technique is that it represents the surface loading by an averaged value determined by locally computed airfoil characteristics. Thus, it does not take into account the chord wise distribution of the induction. Likewise, lifting line methods....... The correction is implemented as an additional correction to the Prandtl tip correction. Where the Prandtl tip correction serves to correct the axisymmetric momentum theory for a finite number of blades (see Goldstein, 1929), the new model further corrects the blade element model to represent the line...... suffer from the problem that the induction from the free wake vortices is only evaluated along a line representing the center of pressure. Hence, the effect from the chord wise distribution of the induction is neglected. As a consequence, the loading in the proximity of the tip is generally found...

  13. Does the terrestrial biosphere have planetary tipping points?

    Science.gov (United States)

    Brook, Barry W; Ellis, Erle C; Perring, Michael P; Mackay, Anson W; Blomqvist, Linus

    2013-07-01

    Tipping points--where systems shift radically and potentially irreversibly into a different state--have received considerable attention in ecology. Although there is convincing evidence that human drivers can cause regime shifts at local and regional scales, the increasingly invoked concept of planetary scale tipping points in the terrestrial biosphere remains unconfirmed. By evaluating potential mechanisms and drivers, we conclude that spatial heterogeneity in drivers and responses, and lack of strong continental interconnectivity, probably induce relatively smooth changes at the global scale, without an expectation of marked tipping patterns. This implies that identifying critical points along global continua of drivers might be unfeasible and that characterizing global biotic change with single aggregates is inapt. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Disproportionate abundance between ectomycorrhizal root tips and their associated mycelia

    DEFF Research Database (Denmark)

    Kjøller, Rasmus

    2006-01-01

    at the times of insertion and retrieval of the mesh bags. Ectomycorrhizal fungi were identified by sequencing the internal transcribed spacer region. In total, 20, 31 and 24 ectomycorrhizal species were recorded from the two root-tip harvests and from the mesh bags, respectively. Boletoid species were......Extensive knowledge of various ectomycorrhizal fungal communities has been obtained over the past 10 years based on molecular identification of the fungi colonizing fine roots. In contrast, only limited information exists about the species composition of ectomycorrhizal hyphae in soil. This study...... compared the ectomycorrhizal external mycelial community with the adjacent root-tip community in a Danish beech forest. Sand-filled in-growth mesh bags were used to trap external mycelia by incubating the mesh bags in the soil for 70 days. The adjacent ectomycorrhizal root-tip communities were recorded...

  15. Stability of helical tip vortices in a rotor far wake

    DEFF Research Database (Denmark)

    Okulov, Valery; Sørensen, Jens Nørkær

    2007-01-01

    , corresponding to Rankine, Gaussian and Scully vortices, at radial extents ranging from the core radius of a tip vortex to several rotor radii. The analysis shows that the stability of tip vortices largely depends on the radial extent of the hub vorticity as well as on the type of vorticity distribution. As part......As a means of analysing the stability of the wake behind a multi-bladed rotor the stability of a multiplicity of helical vortices embedded in an assigned flow field is addressed. In the model the tip vortices in the far wake are approximated by infinitely long helical vortices with constant pitch...... and radius. The work is a further development of a model developed in Okulov (J. Fluid Mech., vol. 521, p. 319) in which the linear stability of N equally azimuthally spaced helical vortices was considered. In the present work the analysis is extended to include an assigned vorticity field due to root...

  16. Characterisation of MFM tip stray fields using Lorentz electron tomography

    CERN Document Server

    Scott, J

    2001-01-01

    considered, as is a possible improved design of DPC detector. distribution a tomographic method must be used. The collection and calibration of the tomographic data series is discussed, including the special sample mounting methods required. To understand the principles behind MFM, the theory behind atomic force microscopy (AFM) is discussed at length in Chapter 3. The extension of AFM to MFM is covered, and the simple point charge analysis of the MFM imaging process is reviewed. A more sophisticated analysis is then presented, based on the knowledge of the MFM point- response function. It is demonstrated that in some cases, the magnetic charge distribution of a samples can be extracted provided that the response function of the MFM tip (related directly to the stray field distribution from the tip) is known. Finally, some specialised MFM techniques are briefly reviewed. In Chapter 4, prototype tips (produced at Sheffield University) coated with a low-coercivity amorphous ferromagnetic alloy (METGLAS 2605SC) ...

  17. Tip Vortex and Wake Characteristics of a Counterrotating Open Rotor

    Science.gov (United States)

    VanZante, Dale E.; Wernet, Mark P.

    2012-01-01

    One of the primary noise sources for Open Rotor systems is the interaction of the forward rotor tip vortex and blade wake with the aft rotor. NASA has collaborated with General Electric on the testing of a new generation of low noise, counterrotating Open Rotor systems. Three-dimensional particle image velocimetry measurements were acquired in the intra-rotor gap of the Historical Baseline blade set. The velocity measurements are of sufficient resolution to characterize the tip vortex size and trajectory as well as the rotor wake decay and turbulence character. The tip clearance vortex trajectory is compared to results from previously developed models. Forward rotor wake velocity profiles are shown. Results are presented in a form as to assist numerical modeling of Open Rotor system aerodynamics and acoustics.

  18. Progress Toward a Bulk Micromachined Tunneling Tip Microaccelerometer

    Science.gov (United States)

    Frank T. Hartley, Ben Dolgen, Paul M. Zavracky

    1995-01-01

    Ultrasensitive accelerometers are needed for microgravity measurement of orbital drag and active isolation systems. We have designed an accelerometer capable of measuring accelerations of the order of 10(i) g. A tunneling tip sensor can be used as a position sensor with a potential performance advantage of two orders of magnitude over capacitive sensors. In this paper, we disclose our progress in the fabrication and measurement of a bulk microaccelerometer which employs a tunneling tip. Fully assembled accelerometers consisting of four separate die have been fabricated. The device employs a unique folded spring system with a low spring constant. To protect the tunneling tip, we have employed electrostatic clamping. Stiction has not been observed, but the required clamping voltage is greater than expected. We have developed a simple model to analyze our results.

  19. Influence of Indenter Tip Geometry on Elastic Deformation during Nanoindentation

    Science.gov (United States)

    Bei, H.; George, E. P.; Hay, J. L.; Pharr, G. M.

    2005-07-01

    Nanoindentation with a Berkovich indenter is commonly used to investigate the mechanical behavior of small volumes of materials. To date, most investigators have made the simplifying assumption that the tip is spherical. In reality, indenter tips are much more complex. Here, we develop a new method to describe the tip shape using the experimentally determined area function of the indenter at small depths (0 100 nm). Our analysis accurately predicts the elastic load-displacement curve and allows the theoretical strength of a material to be determined from pop-in data. Application of our new method to single crystal Cr3Si shows that the predicted theoretical strengths are within 12% of the ideal strength G/2π, where G is the shear modulus.

  20. GaN nanowire tips for nanoscale atomic force microscopy

    Science.gov (United States)

    Behzadirad, Mahmoud; Nami, Mohsen; Rishinaramagalam, Ashwin K.; Feezell, Daniel F.; Busani, Tito

    2017-05-01

    Imaging of high-aspect-ratio nanostructures with sharp edges and straight walls in nanoscale metrology by atomic force microscopy (AFM) has been challenging due to the mechanical properties and conical geometry of the majority of available commercial tips. Here we report on the fabrication of GaN probes for nanoscale metrology of high-aspect-ratio structures to enhance the resolution of AFM imaging and improve the durability of AFM tips. GaN nanowires were fabricated using bottom-up and top-down techniques and bonded to Si cantilevers to scan vertical trenches on Si substrates. Over several scans, the GaN probes demonstrated excellent durability while scanning uneven structures and showed resolution enhancements in topography images, independent of scan direction, compared to commercial Si tips.

  1. Artificial ciliary bundles with nano fiber tip links

    CERN Document Server

    Asadnia, Mohsen; Miao, Jianmin; Triantafyllou, Michael

    2015-01-01

    Mechanosensory ciliary bundles in fishes are the inspiration for carefully engineered artificial flow sensors. We report the development of a new class of ultrasensitive MEMS flow sensors that mimic the intricate morphology of the ciliary bundles, including the stereocilia, tip links, and the cupula, and thereby achieve threshold detection limits that match the biological example. An artificial ciliary bundle is achieved by fabricating closely-spaced arrays of polymer micro-pillars with gradiating heights. Tip links that form the fundamental sensing elements are realized through electrospinning aligned PVDF piezoelectric nano-fibers that link the distal tips of the polymer cilia. An optimized synthesis of hyaluronic acid-methacrylic anhydride hydrogel that results in properties close to the biological cupula, together with drop-casting method are used to form the artificial cupula that encapsulates the ciliary bundle. In testing, fluid drag force causes the ciliary bundle to slide, stretching the flexible nan...

  2. Twelve tips for effective body language for medical educators.

    Science.gov (United States)

    Hale, Andrew J; Freed, Jason; Ricotta, Daniel; Farris, Grace; Smith, C Christopher

    2017-09-01

    A significant proportion of human communication is nonverbal. Although the fields of business and psychology have significant literature on effectively using body language in a variety of situations, there is limited literature on effective body language for medical educators. To provide 12 tips to highlight effective body language strategies and techniques for medical educators. The tips provided are based on our experiences and reflections as clinician-educators and the available literature. The 12 tips presented offer specific strategies to engage learners, balance learner participation, and bring energy and passion to teaching. Medical educators seeking to maximize their effectiveness would benefit from an understanding of how body language affects a learning environment and how body language techniques can be used to engage audiences, maintain attention, control challenging learners, and convey passion for a topic. Understanding and using body language effectively is an important instructional skill.

  3. Solitonlike attractor for blood vessel tip density in angiogenesis

    Science.gov (United States)

    Bonilla, L. L.; Carretero, M.; Terragni, F.

    2016-12-01

    Recently, numerical simulations of a stochastic model have shown that the density of vessel tips in tumor-induced angiogenesis adopts a solitonlike profile [Sci. Rep. 6, 31296 (2016), 10.1038/srep31296]. In this work, we derive and solve the equations for the soliton collective coordinates that indicate how the soliton adapts its shape and velocity to varying chemotaxis and diffusion. The vessel tip density can be reconstructed from the soliton formulas. While the stochastic model exhibits large fluctuations, we show that the location of the maximum vessel tip density for different replicas follows closely the soliton peak position calculated either by ensemble averages or by solving an alternative deterministic description of the density. The simple soliton collective coordinate equations may also be used to ascertain the response of the vessel network to changes in the parameters and thus to control it.

  4. Plasmonic focusing of infrared SNOM tip patterned with asymmetric structures.

    Science.gov (United States)

    Qian, Qinbai; Yu, Haochi; Gou, Peng; Xu, Jie; An, Zhenghua

    2015-05-18

    Several scattering type metal tips patterned with asymmetric metal/dielectric bump gratings are studied and proved to be efficient in focusing light energy into nano 'hot spot'. The dielectric bump tip shows complex mechanisms including local geometric resonance, surface plasmon polariton (SPP) standing wave resonance and Fano effect in the near-field enhancement. Additionally, considering the practical situation, we also demonstrate that, for the case of bending tip surface, the grating coupling method for plasmonic nano-focusing is still applicable if the intervals between neighboring bumps are well designed according to the surface bending curvature. With practical realizations, our results could benefit not only infrared scanning near-field optical microscopes (SNOMs) but also many other applications in nanotechnology such as sensing and lithography.

  5. Influence of double-tip scratch and single-tip scratch on nano-scratching process via molecular dynamics simulation

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Peng [College of Mechanical Science and Engineering, Jilin University, Changchun 130025 (China); Zhao, Hongwei, E-mail: hwzhao@jlu.edu.cn [College of Mechanical Science and Engineering, Jilin University, Changchun 130025 (China); Shi, Chengli; Zhang, Lin; Huang, Hu [College of Mechanical Science and Engineering, Jilin University, Changchun 130025 (China); Ren, Luquan [Key Laboratory of Bionic Engineering Ministry of Education, Jilin University, Changchun 130025 (China)

    2013-09-01

    A three-dimensional molecular dynamics model was proposed to study the influences of scratch feed, depth and crystal orientation on the shape and surface quality of the scratched groove during nano-scratching process. In this paper, comparisons were made between the results of double tips simultaneously scratching the surface and those of single tip successively scratching the surface with the same scratch feed, depth and crystal orientation. EAM potential was used to model the interaction of copper atoms, and Morse potential was used to model the interaction between copper and carbon atoms. The residual profiles of scratched grooves and scratching forces were recorded during the simulations. Simulational results show that when single tip scratches the surface at an extremely small feed, the second time scratch significantly influences the previous groove. The second time scratch has a significant influence on the previous groove by increasing scratch depth. Compared with scratching along crystal orientation [1 0 0], scratching along crystal orientation [0 1 1] and [1 1 1] are easy to obtain two parallel grooves. However, when double tips simultaneously scratch the surface regardless of scratch feed, depth and crystal orientation, two parallel grooves are always obtained. Thus, in order to obtain scratched grooves of high quality, it is quite beneficial to design and machine multiple-tip tools.

  6. Towards rapid nanoscale chemical analysis using tip-enhanced Raman spectroscopy with Ag-coated dielectric tips.

    Science.gov (United States)

    Yeo, Boon-Siang; Schmid, Thomas; Zhang, Weihua; Zenobi, Renato

    2007-04-01

    The influence of dielectric substrates on the Raman scattering activities of Ag overlayers has been investigated. Materials with low refractive indices, such as SiO(2), SiO(x) and AlF(3), were found to provide suitable supporting platforms for Ag films to give strong surface-enhanced Raman scattering for dye molecules when illuminated at 488 nm. This finding was then extended to tip-enhanced Raman scattering (TERS). Huge enhancements of 70-80x, corresponding to net enhancements of >10(4), were observed for brilliant cresyl blue test analyte when Ag-coated tips made from or precoated with low refractive index materials were applied. The yield of fabricated tips that significantly enhance the Raman signals was found to be close to 100%. These findings provide crucial steps towards the use of TERS as a robust technique for rapid chemical imaging with nanometer spatial resolution. Figure Silver-coated dielectric tips for tip-enhanced Raman scattering (TERS) are capable of more than 10,000-fold enhancement.

  7. On the development of a magnetoresistive sensor for blade tip timing and blade tip clearance measurement systems

    Science.gov (United States)

    Tomassini, R.; Rossi, G.; Brouckaert, J.-F.

    2016-10-01

    A simultaneous blade tip timing (BTT) and blade tip clearance (BTC) measurement system enables the determination of turbomachinery blade vibrations and ensures the monitoring of the existing running gaps between the blade tip and the casing. This contactless instrumentation presents several advantages compared to the well-known telemetry system with strain gauges, at the cost of a more complex data processing procedure. The probes used can be optical, capacitive, eddy current as well as microwaves, everyone with its dedicated electronics and many existing different signal processing algorithms. Every company working in this field has developed its own processing method and sensor technology. Hence, repeating the same test with different instrumentations, the answer is often different. Moreover, rarely it is possible to achieve reliability for in-service measurements. Developments are focused on innovative instrumentations and a common standard. This paper focuses on the results achieved using a novel magnetoresistive sensor for simultaneous tip timing and tip clearance measurements. The sensor measurement principle is described. The sensitivity to gap variation is investigated. In terms of measurement of vibrations, experimental investigations were performed at the Air Force Institute of Technology (ITWL, Warsaw, Poland) in a real aeroengine and in the von Karman Institute (VKI) R2 compressor rig. The advantages and limitations of the magnetoresistive probe for turbomachinery testing are highlighted.

  8. Optical method for automated measurement of glass micropipette tip geometry.

    Science.gov (United States)

    Stockslager, Max A; Capocasale, Christopher M; Holst, Gregory L; Simon, Michael D; Li, Yuanda; McGruder, Dustin J; Rousseau, Erin B; Stoy, William A; Sulchek, Todd; Forest, Craig R

    2016-10-01

    Many experimental biological techniques utilize hollow glass needles called micropipettes to perform fluid extraction, cell manipulation, and electrophysiological recordings For electrophysiological recordings, micropipettes are typically fabricated immediately before use using a "pipette puller", which uses open-loop control to heat a hollow glass capillary while applying a tensile load. Variability between manufactured micropipettes requires a highly trained operator to qualitatively inspect each micropipette; typically this is achieved by viewing the pipette under 40-100x magnification in order to ensure that the tip has the correct shape (e.g., outer diameter, cone angle, taper length). Since laboratories may use hundreds of micropipettes per week, significant time demands are associated with micropipette inspection. Here, we have automated the measurement of micropipette tip outer diameter and cone angle using optical microscopy. The process features repeatable constraint of the micropipette, quickly and automatically moving the micropipette to bring its tip into the field of view, focusing on the tip, and computing tip outer diameter and cone angle measurements from the acquired images by applying a series of image processing algorithms. As implemented on a custom automated microscope, these methods achieved, with 95% confidence, ±0.38 µm repeatability in outer diameter measurement and ±5.45° repeatability in cone angle measurement, comparable to a trained human operator. Accuracy was evaluated by comparing optical pipette measurements with measurements obtained using scanning electron microscopy (SEM); optical outer diameter measurements differed from SEM by 0.35 ± 0.36 µm and optical cone angle measurements differed from SEM by -0.23 ± 2.32°. The algorithms we developed are adaptable to most commercial automated microscopes and provide a skill-free route to rapid, quantitative measurement of pipette tip geometry with high resolution, accuracy, and

  9. Finite Element Model and Validation of Nasal Tip Deformation.

    Science.gov (United States)

    Manuel, Cyrus T; Harb, Rani; Badran, Alan; Ho, David; Wong, Brian J F

    2017-03-01

    Nasal tip mechanical stability is important for functional and cosmetic nasal airway surgery. Palpation of the nasal tip provides information on tip strength to the surgeon, though it is a purely subjective assessment. Providing a means to simulate nasal tip deformation with a validated model can offer a more objective approach in understanding the mechanics and nuances of the nasal tip support and eventual nasal mechanics as a whole. Herein we present validation of a finite element (FE) model of the nose using physical measurements recorded using an ABS plastic-silicone nasal phantom. Three-dimensional photogrammetry was used to capture the geometry of the phantom at rest and while under steady state load. The silicone used to make the phantom was mechanically tested and characterized using a linear elastic constitutive model. Surface point clouds of the silicone and FE model were compared for both the loaded and unloaded state. The average Hausdorff distance between actual measurements and FE simulations across the nose were 0.39 ± 1.04 mm and deviated up to 2 mm at the outermost boundaries of the model. FE simulation and measurements were in near complete agreement in the immediate vicinity of the nasal tip with millimeter accuracy. We have demonstrated validation of a two-component nasal FE model, which could be used to model more complex modes of deformation where direct measurement may be challenging. This is the first step in developing a nasal model to simulate nasal mechanics and ultimately the interaction between geometry and airflow.

  10. Results of Dynamic Calibration of Tipping-Bucket Rain Gauges

    Science.gov (United States)

    Kvicera, V.; Grabner, M.

    2009-04-01

    Experimental research in the Department of Frequency Engineering in the Czech Metrology Institute (CMI) in Prague, the Czech Republic, is focused on stability of received signal on terrestrial radio and optical paths. Rain can cause serious attenuation of electromagnetic waves in the frequency bands over 10 GHz. Therefore, our experimental research is also focused on our own meteorological measurement in the vicinity of experimental radio and optical paths. The heated tipping-bucket raingauge MR3H manufactured by Meteoservis, the Czech Republic, with the collector area of 500 cm2 and the rain amount per tip of 0.1 mm is used at CMI for the measurement of rainfall intensities. The time of tips is recorded with uncertainty of 0.1 second. The obtained time of tips are stored by PC and recorded on CD-ROM. It is generally known higher rainfall intensities measured by tipping-bucket rain gauges are underestimated. Therefore, after static calibration the tipping-bucket rain gauge was dynamically calibrated by water flowmeters. The Brooks FLOMEGA Flow Meters models 5882 and 3750 were used for the rain gauge calibration in the range from 2.6 mm/h to 530 mm/h. The used method of dynamic calibration of raingauges and our experience obtained will be described. The dependence of the measured rain intensity on the reference rain intensity (calibration curve) will be presented. Both the results obtained and the influence of dynamic calibration on our results concerning attenuation of electromagnetic waves due to rain will be discussed. Ministry of Education, Youth and Sports of the Czech Republic under the Project No. OC09076 supported the described work.

  11. Mental vulnerability as a predictor of early mortality

    DEFF Research Database (Denmark)

    Eplov, Lene Falgaard; Jørgensen, Torben; Birket-Smith, Morten

    2005-01-01

    BACKGROUND: Studies have demonstrated that mental vulnerability (ie, a tendency to experience psychosomatic symptoms or inadequate interpersonal interactions) is associated with various diseases. The objective of our study is to evaluate whether mental vulnerability is a risk factor for early...... mortality. METHODS: We conducted a prospective cohort study of 3 random samples of the population in Copenhagen County, Denmark selected in 1976, 1982-1984, and 1991 (n = 6435). Baseline data collection included measures of mental vulnerability, social factors, comorbidity, biologic risk markers (eg, blood...... of mortality as the result of natural causes. The association between mental vulnerability and survival was examined using Kaplan-Meir plots and Cox proportional-hazard models adjusting for possible confounding factors. RESULTS: With respect to mental vulnerability, 79% of the sample was classified...

  12. Oracle internals tips, tricks, and techniques for DBAs

    CERN Document Server

    Burleson, Donald K

    2001-01-01

    If you are a typical Oracle professional, you don't have the luxury of time to keep up with new technology and read all the new manuals to understand each new feature of the latest release from Oracle. You need a comprehensive source of information and in-depth tips and techniques for using the new technology. You need Oracle Internals: Tips, Tricks, and Techniques for DBAs.Oracle has evolved from a simple relational database into one of the most complex e-commerce platforms ever devised. It's not enough for you to understand just the Oracle database. You must also understand the components of

  13. Mechanochemistry Induced Using Force Exerted by a Functionalized Microscope Tip

    DEFF Research Database (Denmark)

    Zhang, Yajie; Wang, Yongfeng; Lü, Jing-Tao

    2017-01-01

    Atomic-scale mechanochemistry is realized from force exerted by a C60 -functionalized scanning tunneling microscope tip. Two conformers of tin phthalocyanine can be prepared on coinage-metal surfaces. A transition between these conformers is induced on Cu(111) and Ag(100). Density-functional calc......Atomic-scale mechanochemistry is realized from force exerted by a C60 -functionalized scanning tunneling microscope tip. Two conformers of tin phthalocyanine can be prepared on coinage-metal surfaces. A transition between these conformers is induced on Cu(111) and Ag(100). Density...

  14. Spontaneous migration of central venous catheter tip following extubation

    Directory of Open Access Journals (Sweden)

    Balaji Prabaharan

    2014-01-01

    Full Text Available Migration of the tip of central venous catheters is not an uncommon event and the mechanism for this is not clear. Increased intrathoracic pressure due to coughing, sneezing or weight lifting, changing the body position or physical movements such as abduction or adduction of the arms is thought to be the cause of such migration. We present here a case of a patient with a port catheter tip that migrated from the left subclavian to the superior vene cava following extubation.

  15. Electrochemical etching of sharp tips for STM reveals singularity

    DEFF Research Database (Denmark)

    Quaade, Ulrich; Oddershede, Lene

    2002-01-01

    Electrochemical etching of metal wires is widely used to produce atomically sharp tips for use in scanning tunneling microscopy (STM). In this letter we uncover the existence of a finite-time singularity in the process: Several of the physical parameters describing the system exhibit scaling...... towards and away from a particular singular point in time, exactly the time at which the wire breaks. The obtained scaling exponents coincide with exponents reported from other singular dynamical systems. The results also provide knowledge of how to control STM tip properties on the nano-scale....

  16. The Effect of Patriotic Messages on Restaurant Tipping

    OpenAIRE

    Seiter, John S.; Gass, R. H.

    2005-01-01

    This study compared the effectiveness of 2 types of patriotic messages with a warmth/ ingratiation message and a control condition on restaurant tipping. Two female food servers waited on 100 parties eating dinner. When diners were finished with their meals, servers left them 1 of 4 messages on their checks: “Have a Nice Day,”“God Bless America,”“United We Stand,” or no message. Results indicated that parties who received the “United We Stand” message left significantly higher tips than did t...

  17. Catheter tip erosion due to Rotablator burr: An unusual complication.

    Science.gov (United States)

    Hurt, Christopher; Schurtz, Guillaume; Lemesle, Gilles; Sudre, Arnaud; Van Belle, Eric; Delhaye, Cédric

    2016-01-01

    We report the occurrence of catheter tip erosion during use of a Rotablator, a rare but serious complication. A heavily calcified lesion of the right coronary artery ostium required use of a Rotablator, and the need for strong push led to the choice of an Amplatz Left guiding catheter. The traction of the catheter toward the ostium and the subsequent angle generated led to friction of the burr against the catheter and the erosion of its tip. If judged essential to get strong support, the Amplatz catheter should be used with caution in this setting. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. 50 tips and tricks for MongoDB developers

    CERN Document Server

    Chodorow, Kristina

    2011-01-01

    Getting started with MongoDB is easy, but once you begin building applications with it, you'll face some complex issues. What are the tradeoffs between normalized and denormalized data? How do you handle replica set failure and failover? This collection of MongoDB tips, tricks, and hacks helps you resolve issues with everything from application design and implementation to data safety and monitoring. You get specific guidance in five topic areas directly from engineers at 10gen, the company that develops and supports this open source database: Application Design Tips: What to keep in mind wh

  19. Case report of recurrent acute appendicitis in a residual tip.

    LENUS (Irish Health Repository)

    O'Leary, Donal P

    2010-01-01

    INTRODUCTION: Residual appendicitis involving the stump of the appendix has been well described in the literature in the past. CASE REPORT: We report the case of a 43 year old male with acute onset of abdominal pain who had undergone an appendicectomy ten years previously. Ultrasound revealed the presence of an inflamed tubular structure. Subsequent laparotomy and histology confirmed that this structure was an inflamed residual appendiceal tip. CONCLUSION: Residual tip appendicitis has not been reported in the literature previously and should be considered in the differential diagnosis of localised peritonitis in a patient with a history of a previous open appendicectomy.

  20. Reproducible SERS substrates on optical fiber tips by nanosphere lithography

    Science.gov (United States)

    Pisco, M.; Galeotti, F.; Quero, G.; Grisci, G.; Micco, A.; Mercaldo, L. V.; Delli Veneri, P.; Cutolo, A.; Cusano, A.

    2017-04-01

    This paper reports on the assessment of a simple and economical self-assembly methodology to obtain reproducible substrates onto the optical fiber tip for surface-enhanced Raman spectroscopy (SERS) applications. The method relies on the use of the nanosphere lithography of the optical fiber end facet. A careful analysis has been carried out to investigate the capability of the proposed procedure to realize repeatable pattern on the optical fiber tip. Finally, we demonstrate the effective application of the patterned OFTs as SERS nanoprobes.