WorldWideScience

Sample records for surfacing design guide

  1. Robust surface reconstruction by design-guided SEM photometric stereo

    Science.gov (United States)

    Miyamoto, Atsushi; Matsuse, Hiroki; Koutaki, Gou

    2017-04-01

    We present a novel approach that addresses the blind reconstruction problem in scanning electron microscope (SEM) photometric stereo for complicated semiconductor patterns to be measured. In our previous work, we developed a bootstrapping de-shadowing and self-calibration (BDS) method, which automatically calibrates the parameter of the gradient measurement formulas and resolves shadowing errors for estimating an accurate three-dimensional (3D) shape and underlying shadowless images. Experimental results on 3D surface reconstruction demonstrated the significance of the BDS method for simple shapes, such as an isolated line pattern. However, we found that complicated shapes, such as line-and-space (L&S) and multilayered patterns, produce deformed and inaccurate measurement results. This problem is due to brightness fluctuations in the SEM images, which are mainly caused by the energy fluctuations of the primary electron beam, variations in the electronic expanse inside a specimen, and electrical charging of specimens. Despite these being essential difficulties encountered in SEM photometric stereo, it is difficult to model accurately all the complicated physical phenomena of electronic behavior. We improved the robustness of the surface reconstruction in order to deal with these practical difficulties with complicated shapes. Here, design data are useful clues as to the pattern layout and layer information of integrated semiconductors. We used the design data as a guide of the measured shape and incorporated a geometrical constraint term to evaluate the difference between the measured and designed shapes into the objective function of the BDS method. Because the true shape does not necessarily correspond to the designed one, we use an iterative scheme to develop proper guide patterns and a 3D surface that provides both a less distorted and more accurate 3D shape after convergence. Extensive experiments on real image data demonstrate the robustness and effectiveness

  2. Design of guided Bloch surface wave resonance bio-sensors with high sensitivity

    Science.gov (United States)

    Kang, Xiu-Bao; Wen, Li-Wei; Wang, Zhi-Guo

    2017-01-01

    The sensing performance of bio-sensors based on guided Bloch surface wave (BSW) resonance (GBR) is studied. GBR is realized by coupling the propagating electromagnetic wave with BSW on one side of a one-dimensional photonic crystal slab via the grating on the other side. The sensitivity of the designed bio-sensors is proportional to the grating constant when the wavelength spectrum is analyzed, and inversely proportional to the normal wave vector of the incident electromagnetic wave when the angular spectrum is resolved. For a GBR bio-sensor designed to operate near 70° angle of incidence from air, the angular sensitivity is very high, reaching 128 deg RIU-1. The sensitivity can be substantially increased by designing bio-sensors for operating at larger angles of incidence.

  3. Control system design guide

    Energy Technology Data Exchange (ETDEWEB)

    Sellers, David; Friedman, Hannah; Haasl, Tudi; Bourassa, Norman; Piette, Mary Ann

    2003-05-01

    The ''Control System Design Guide'' (Design Guide) provides methods and recommendations for the control system design process and control point selection and installation. Control systems are often the most problematic system in a building. A good design process that takes into account maintenance, operation, and commissioning can lead to a smoothly operating and efficient building. To this end, the Design Guide provides a toolbox of templates for improving control system design and specification. HVAC designers are the primary audience for the Design Guide. The control design process it presents will help produce well-designed control systems that achieve efficient and robust operation. The spreadsheet examples for control valve schedules, damper schedules, and points lists can streamline the use of the control system design concepts set forth in the Design Guide by providing convenient starting points from which designers can build. Although each reader brings their own unique questions to the text, the Design Guide contains information that designers, commissioning providers, operators, and owners will find useful.

  4. Pneumatic conveying design guide

    CERN Document Server

    Mills, David

    1990-01-01

    Pneumatic Conveying Design Guide is a guide for the design of pneumatic conveying systems and includes detailed data and information on the conveying characteristics of a number of materials with a wide range of properties. This book includes logic diagrams for design procedures and scaling parameters for the conveying line configuration. It also explains how to improve the performance of pneumatic conveyors by optimizing, uprating, and extending the system or adapting it for a change of material. This book consists of 15 chapters divided into three sections and opens with an overview of the s

  5. Surface plasmon resonance sensors a materials guide to design and optimization

    CERN Document Server

    Oliveira, Leiva Casemiro; Thirstrup, Carsten; Neff, Helmut Franz

    2015-01-01

    This book addresses the important physical phenomenon of Surface Plasmon Resonance or Surface Plasmon Polaritons in thin metal films, a phenomenon which is exploited in the design of a large variety of physico-chemical optical sensors. In this treatment, crucial materials aspects for design and optimization of SPR sensors are investigated and outlined in detail. The text covers the selection of nanometer thin metal films, ranging from free-electron to the platinum type conductors, along with their combination with a large variety of dielectric substrate materials, and associated individual layer and opto-geometric arrangements. Furthermore, as-yet hardly explored SPR features of selected metal–metal and metal–dielectric super lattices are included in this report. An in-depth multilayer Fresnel evaluation provides the mathematical tool for this optical analysis, which otherwise relies solely on experimentally determined electro-optical materials parameters.

  6. Curves and surfaces for computer-aided geometric design a practical guide

    CERN Document Server

    Farin, Gerald

    1992-01-01

    A leading expert in CAGD, Gerald Farin covers the representation, manipulation, and evaluation of geometric shapes in this the Third Edition of Curves and Surfaces for Computer Aided Geometric Design. The book offers an introduction to the field that emphasizes Bernstein-Bezier methods and presents subjects in an informal, readable style, making this an ideal text for an introductory course at the advanced undergraduate or graduate level.The Third Edition includes a new chapter on Topology, offers new exercises and sections within most chapters, combines the material on Geometric Continuity i

  7. Design and control of an embedded vision guided robotic fish with multiple control surfaces.

    Science.gov (United States)

    Yu, Junzhi; Wang, Kai; Tan, Min; Zhang, Jianwei

    2014-01-01

    This paper focuses on the development and control issues of a self-propelled robotic fish with multiple artificial control surfaces and an embedded vision system. By virtue of the hybrid propulsion capability in the body plus the caudal fin and the complementary maneuverability in accessory fins, a synthesized propulsion scheme including a caudal fin, a pair of pectoral fins, and a pelvic fin is proposed. To achieve flexible yet stable motions in aquatic environments, a central pattern generator- (CPG-) based control method is employed. Meanwhile, a monocular underwater vision serves as sensory feedback that modifies the control parameters. The integration of the CPG-based motion control and the visual processing in an embedded microcontroller allows the robotic fish to navigate online. Aquatic tests demonstrate the efficacy of the proposed mechatronic design and swimming control methods. Particularly, a pelvic fin actuated sideward swimming gait was first implemented. It is also found that the speeds and maneuverability of the robotic fish with coordinated control surfaces were largely superior to that of the swimming robot propelled by a single control surface.

  8. Abbreviated guide pneumatic conveying design guide

    CERN Document Server

    Mills, David

    1990-01-01

    Abbreviated Guide: Pneumatic Conveying Design Guide describes the selection, design, and specification of conventional pneumatic conveying systems. The design procedure uses previous test data on the materials to be conveyed. The book also discusses system economics, operating costs, the choice of appropriate components or systems, system control, and system flexibility. The design system involves the type of conveying system for installation, the pipeline parameters, and also the plant components. System selection covers the properties of the material to be conveyed, plant layout, material pr

  9. Topology-guided design and syntheses of highly stable mesoporous porphyrinic zirconium metal-organic frameworks with high surface area.

    Science.gov (United States)

    Liu, Tian-Fu; Feng, Dawei; Chen, Ying-Pin; Zou, Lanfang; Bosch, Mathieu; Yuan, Shuai; Wei, Zhangwen; Fordham, Stephen; Wang, Kecheng; Zhou, Hong-Cai

    2015-01-14

    Through a topology-guided strategy, a series of Zr6-containing isoreticular porphyrinic metal-organic frameworks (MOFs), PCN-228, PCN-229, and PCN-230, with ftw-a topology were synthesized using the extended porphyrinic linkers. The bulky porphyrin ring ligand effectively prevents the network interpenetration which often appears in MOFs with increased linker length. The pore apertures of the structures range from 2.5 to 3.8 nm, and PCN-229 demonstrates the highest porosity and BET surface area among the previously reported Zr-MOFs. Additionally, by changing the relative direction of the terminal phenyl rings, this series replaces a Zr8 cluster with a smaller Zr6 cluster in a topologically identical framework. The high connectivity of the Zr6 cluster yields frameworks with enhanced stability despite high porosity and ultralarge linker. As a representative example, PCN-230, constructed with the most extended porphyrinic linker, shows excellent stability in aqueous solutions with pH values ranging from 0 to 12 and demonstrates one of the highest pH tolerances among all porphyrinic MOFs. This work not only presents a successful example of rational design of MOFs with desired topology, but also provides a strategy for construction of stable mesoporous MOFs.

  10. Guide for surface coal mine reclamation plans

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-11-15

    The purpose of the guide is to provide a framework for Nova Scotia's coal mining community to consult during reclamation planning and environmental assessment. The guide describe the best management practices for application to surface mine reclamation. Principles of reclamation, standard submission requirements for a reclamation plan, planning for reclamation, landscape design, and revegetation, and methods for site preparation, monitoring, and maintenance are discussed. Backfilling, flooded excavation management, and other options are outlined. The reclamation plan must consider decommissioning of equipment and infrastructure, water retention and treatment ponds, acid rock drainage control and monitoring, site monitoring, watercourse management, and public safety. A glossary is included.

  11. REC Tracking Systems Design Guide

    Energy Technology Data Exchange (ETDEWEB)

    Meredith Wingate

    2004-02-03

    OAK-B135 The Design Guide is presented in three parts. Section II describes the need for REC tracking, the two principal tracking methods available, and, in simple terms, the operation of certificate-based systems. Section III presents the major issues in the design of certificate-based tracking systems and discusses the advantages and disadvantages of alternative solutions. Finally, Section IV offers design principles or recommendations for most of these issues.

  12. Interior Design: Teacher's Instructional Guide.

    Science.gov (United States)

    Hays, Tricia

    This teacher's instructional guide, which is part of a family and consumer sciences education series focusing on a broad range of employment opportunities, is intended to assist teachers responsible for teaching one- and two-year interior design programs for Texas high school students. The following are among the items included: (1) introductory…

  13. Interior Design: Teacher's Instructional Guide.

    Science.gov (United States)

    Hays, Tricia

    This teacher's instructional guide, which is part of a family and consumer sciences education series focusing on a broad range of employment opportunities, is intended to assist teachers responsible for teaching one- and two-year interior design programs for Texas high school students. The following are among the items included: (1) introductory…

  14. Students' guide to program design

    CERN Document Server

    Robertson, Lesley Anne

    1992-01-01

    Students' Guide to Program Design is a textbook on program design. This textbook approaches program design by using structures programming techniques and pseudocode to develop a solution algorithm. Divided into 10 chapters, the book begins with a basic explanation of structured programming techniques, top-down development, and modular design. This discussion is followed by detailed concepts of the syntax of pseudocode; methods of defining the problem; the application of basic control structures in the development of the solution algorithm; desk checking techniques; hierarchy charts; and module

  15. Practical guide to surface science and spectroscopy

    CERN Document Server

    Chung, Yip-Wah

    2001-01-01

    Practical Guide to Surface Science and Spectroscopy provides a practical introduction to surface science as well as describes the basic analytical techniques that researchers use to understand what occurs at the surfaces of materials and at their interfaces. These techniques include auger electron spectroscopy, photoelectron spectroscopy, inelastic scattering of electrons and ions, low energy electron diffraction, scanning probe microscopy, and interfacial segregation. Understanding the behavior of materials at their surfaces is essential for materials scientists and engineers as they design and fabricate microelectronics and semiconductor devices. The book gives over 100 examples, discussion questions and problems with varying levels of difficulty. Included with this book is a CD-ROM, which not only contains the same information, but also provides many elements of animation and interaction that are not easily emulated on paper. In diverse subject matters ranging from the operation of ion pumps, computer-...

  16. A provisional guide to surface acclimatization

    CSIR Research Space (South Africa)

    Bredell, GAG

    1966-02-01

    Full Text Available stream_source_info RR 16_66 A provisional guide to surface acclimatization COMRO 1966.pdf.txt stream_content_type text/plain stream_size 23 Content-Encoding ISO-8859-1 stream_name RR 16_66 A provisional guide to surface...

  17. Electronic-Power-Transformer Design Guide

    Science.gov (United States)

    Schwarze, G. E.; Lagadinos, J. C.; Ahearn, J. F.

    1983-01-01

    Compilation of information on design procedures, electrical properties, and fabrication. Guide provides information on design procedures; magnetic and insulating material electrical properties; impregnating, encapsulating and processing techniques.

  18. Graphic Design Career Guide 2. Revised Edition.

    Science.gov (United States)

    Craig, James

    The graphic design field is diverse and includes many areas of specialization. This guide introduces students to career opportunities in graphic design. The guide is organized in four parts. "Part One: Careers in Graphic Design" identifies and discusses the various segments of the graphic design industry, including: Advertising, Audio-Visual, Book…

  19. A surface-electrode quadrupole guide for electrons

    Energy Technology Data Exchange (ETDEWEB)

    Hoffrogge, Johannes Philipp

    2012-12-19

    This thesis reports on the design and first experimental realization of a surface-electrode quadrupole guide for free electrons. The guide is based on a miniaturized, planar electrode layout and is driven at microwave frequencies. It confines electrons in the near-field of the microwave excitation, where strong electric field gradients can be generated without resorting to resonating structures or exceptionally high drive powers. The use of chip-based electrode geometries allows the realization of versatile, microstructured potentials with the perspective of novel quantum experiments with guided electrons. I present the design, construction and operation of an experiment that demonstrates electron confinement in a planar quadrupole guide for the first time. To this end, electrons with kinetic energies from one to ten electron-volts are guided along a curved electrode geometry. The stability of electron guiding as a function of drive parameters and electron energy has been studied. A comparison with numerical particle tracking simulations yields good qualitative agreement and provides a deeper understanding of the electron dynamics in the guiding potential. Furthermore, this thesis gives a detailed description of the design of the surface-electrode layout. This includes the development of an optimized coupling structure to inject electrons into the guide with minimum transverse excitation. I also discuss the extension of the current setup to longitudinal guide dimensions that are comparable to or larger than the wavelength of the drive signal. This is possible with a modified electrode layout featuring elevated signal conductors. Electron guiding in the field of a planar, microfabricated electrode layout allows the generation of versatile and finely structured guiding potentials. One example would be the realization of junctions that split and recombine a guided electron beam. Furthermore, it should be possible to prepare electrons in low-lying quantum mechanical

  20. Interactive Design of Developable Surfaces

    KAUST Repository

    Tang, Chengcheng

    2016-01-15

    We present a new approach to geometric modeling with developable surfaces and the design of curved-creased origami. We represent developables as splines and express the nonlinear conditions relating to developability and curved folds as quadratic equations. This allows us to utilize a constraint solver, which may be described as energy-guided projection onto the constraint manifold, and which is fast enough for interactive modeling. Further, a combined primal-dual surface representation enables us to robustly and quickly solve approximation problems.

  1. Experiment Design and Analysis Guide - Neutronics & Physics

    Energy Technology Data Exchange (ETDEWEB)

    Misti A Lillo

    2014-06-01

    The purpose of this guide is to provide a consistent, standardized approach to performing neutronics/physics analysis for experiments inserted into the Advanced Test Reactor (ATR). This document provides neutronics/physics analysis guidance to support experiment design and analysis needs for experiments irradiated in the ATR. This guide addresses neutronics/physics analysis in support of experiment design, experiment safety, and experiment program objectives and goals. The intent of this guide is to provide a standardized approach for performing typical neutronics/physics analyses. Deviation from this guide is allowed provided that neutronics/physics analysis details are properly documented in an analysis report.

  2. General Design for CARR Neutron Guide System

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A neutron guide system has been designed and partly installed at the China Advanced Research Reactor (CARR) to transport cold neutrons from the cold neutron source (CNS) to several instruments,which are situated in a separate guide hall of 30 m×60 m.

  3. Designing and Implementing Multicultural Initiatives: Guiding Principles

    Science.gov (United States)

    Watt, Sherry K.

    2013-01-01

    This chapter provides guiding principles for designing and implementing successful multicultural initiatives. A rationale for why these elements transcend both higher education and student affairs settings is presented. In addition to providing guiding principles, this chapter includes advice for socially and politically conscious-minded…

  4. User Interactive Guided Search Design Environment Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Phoenix Integration's vision is to create an intuitive human-in-the-loop engineering design environment called Guided Search that leverages recent advances in...

  5. Design intent tool: User guide

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Evan; Abell, Daniel; Bell, Geoffrey; Faludi, Jeremy; Greenberg, Steve; Hitchcock, Rob; Piette, Mary Ann; Sartor, Dalei; Stum, Karl

    2002-08-23

    This database tool provides a structured approach to recording design decisions that impact a facility's design intent in areas such as energy efficiency.Owners and de signers alike can plan, monitor and verify that a facility's design intent is being met during each stage of the design process. Additionally, the Tool gives commissioning agents, facility operators and future owners and renovators an understanding of how the building and its subsystems are intended to operate, and thus track and benchmark performance.

  6. 50% Advanced Energy Design Guides: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Bonnema, E.; Leach, M.; Pless, S.; Liu, B.; Wang, W.; Thornton, B.; Williams, J.

    2012-07-01

    This paper presents the process, methodology, and assumptions for the development of the 50% Energy Savings Advanced Energy Design Guides (AEDGs), a design guidance document that provides specific recommendations for achieving 50% energy savings above the requirements of ANSI/ASHRAE/IESNA Standard 90.1-2004 in four building types: (1) Small to medium office buildings, (2) K-12 school buildings, (3) Medium to big box retail buildings, (4) Large hospital buildings.

  7. A guide to printed circuit board design

    CERN Document Server

    Hamilton, Charles

    1984-01-01

    A Guide to Printed Circuit Board Design discusses the basic design principles of printed circuit board (PCB). The book consists of nine chapters; each chapter provides both text discussion and illustration relevant to the topic being discussed. Chapter 1 talks about understanding the circuit diagram, and Chapter 2 covers how to compile component information file. Chapter 3 deals with the design layout, while Chapter 4 talks about preparing the master artworks. The book also covers generating computer aided design (CAD) master patterns, and then discusses how to prepare the production drawing a

  8. Design and tests of an adaptive focusing neutron guide

    Energy Technology Data Exchange (ETDEWEB)

    Valicu, Roxana Georgiana

    2012-08-23

    This work contains the Monte Carlo Simulations, as well as the first tests with an adaptive focusing neutron guide for creating a focus that does not depend on the wavelength of the incoming neutrons. All known neutron guides consist of a rectangular shape, built out of four glass plates. The inner side of the guide is coated with a complex structure of metal layers. This reflects and guides the neutrons (in analogy with the reflection of the light). For beam focusing neutron guides with fixed curvature can be built. For most experiments it is important that the beam is focused on to a small surface of the sample. In the case of focusing guides with fixed curvature it has been observed that the focusing (dimension and position of the beam focus) is wavelength dependent. This is why for measurements that are performed with different wavelengths it is very important to change the curvature of the neutron guide in order to obtain optimal results. In this work we have designed, constructed and tested a guide where we can change the curvature during the experiment. In this way we can obtain a variable curvature in horizontal as well as in vertical direction. For a curvature in the horizontal or vertical direction it is not necessary to move all four walls, only two of the opposed plates. The element that changes the curvature of the guide consists of an acting element (piezomotor) as well as a rod that can be operated by the piezomotor and that acts through a lever onto the plate. The action of a force and a consecutive torsion momentum at the free end of the plate changes the curvature of the whole plate in an almost parabolic way. Making use of the Monte Carlo simulations we were able to determine the optimal curvature for each wavelength of a neutron guide for the spectrometer TOFTOF installed at the Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II). First tests have shown that with an adaptive focusing guide one can gain up to a factor three in intensity at

  9. CRISPR guide RNA design for research applications.

    Science.gov (United States)

    Mohr, Stephanie E; Hu, Yanhui; Ewen-Campen, Benjamin; Housden, Benjamin E; Viswanatha, Raghuvir; Perrimon, Norbert

    2016-09-01

    The rapid rise of CRISPR as a technology for genome engineering and related research applications has created a need for algorithms and associated online tools that facilitate design of on-target and effective guide RNAs (gRNAs). Here, we review the state of the art in CRISPR gRNA design for research applications of the CRISPR-Cas9 system, including knockout, activation, and inhibition. Notably, achieving good gRNA design is not solely dependent on innovations in CRISPR technology. Good design and design tools also rely on availability of high-quality genome sequence and gene annotations, as well as on availability of accumulated data regarding off-targets and effectiveness metrics.

  10. Bidirectional bending splitter of designer surface plasmons

    Science.gov (United States)

    Jin Zhou, Yong; Jiang, Quan; Jun Cui, Tie

    2011-09-01

    We propose and experimentally verify a bidirectional bending splitter of designer surface plasmons which is composed of two metallic gratings of trapezoid grooves. A metal wire is used to excite the designer surface plasmons propagating along the gratings. A full-wave numerical method has been used to simulate the performance of the bending splitter. The experimental verifications in the microwave frequencies have excellent agreements to the simulations. It is demonstrated that the splitter can not only split the electromagnetic waves at different frequencies, but also guide the electromagnetic waves effectively for large-angle bending.

  11. Designing bioinspired superoleophobic surfaces

    Science.gov (United States)

    Brown, Philip S.; Bhushan, Bharat

    2016-01-01

    Nature provides a range of functional surfaces, for example, water-repellent or superhydrophobic surfaces, most common among them the lotus leaf. While water-repellency is widespread in nature, oil-repellency is typically limited to surfaces submerged in water, such as fish scales. To achieve oleophobicity in air, inspiration must be taken from natural structures and chemistries that are not readily available in nature need to be introduced. Researchers usually turn to fluorinated materials to provide the low surface energy that, when combined with bioinspired surface topography, is the key to unlocking oil-repellency. This review presents the state-of-the-art in the fabrication of superoleophobic surfaces.

  12. Urban road design according to NACTO Urban Street Design Guide

    OpenAIRE

    Velkavrh, Lara

    2016-01-01

    Urban road design according to NACTO follows the vision of traffic calming with visual elements. Gradual restoration of urban traffic areas will be presented according to american guidelines of NACTO Association, which published a book in 2013 called Urban Street Design Guide. Each type of existing roads in the urban area (the main street, the road in the neighborhood, residential shared street) can be, step by step, reconstructed with individual structural elements to ensure greater safety f...

  13. A pragmatic guide to multiphoton microscope design.

    Science.gov (United States)

    Young, Michael D; Field, Jeffrey J; Sheetz, Kraig E; Bartels, Randy A; Squier, Jeff

    2015-06-30

    Multiphoton microscopy has emerged as a ubiquitous tool for studying microscopic structure and function across a broad range of disciplines. As such, the intent of this paper is to present a comprehensive resource for the construction and performance evaluation of a multiphoton microscope that will be understandable to the broad range of scientific fields that presently exploit, or wish to begin exploiting, this powerful technology. With this in mind, we have developed a guide to aid in the design of a multiphoton microscope. We discuss source selection, optical management of dispersion, image-relay systems with scan optics, objective-lens selection, single-element light-collection theory, photon-counting detection, image rendering, and finally, an illustrated guide for building an example microscope.

  14. Designing bioinspired superoleophobic surfaces

    Directory of Open Access Journals (Sweden)

    Philip S. Brown

    2016-01-01

    Full Text Available Nature provides a range of functional surfaces, for example, water-repellent or superhydrophobic surfaces, most common among them the lotus leaf. While water-repellency is widespread in nature, oil-repellency is typically limited to surfaces submerged in water, such as fish scales. To achieve oleophobicity in air, inspiration must be taken from natural structures and chemistries that are not readily available in nature need to be introduced. Researchers usually turn to fluorinated materials to provide the low surface energy that, when combined with bioinspired surface topography, is the key to unlocking oil-repellency. This review presents the state-of-the-art in the fabrication of superoleophobic surfaces.

  15. Designing bioinspired superoleophobic surfaces

    OpenAIRE

    Philip S. Brown; Bharat Bhushan

    2016-01-01

    Nature provides a range of functional surfaces, for example, water-repellent or superhydrophobic surfaces, most common among them the lotus leaf. While water-repellency is widespread in nature, oil-repellency is typically limited to surfaces submerged in water, such as fish scales. To achieve oleophobicity in air, inspiration must be taken from natural structures and chemistries that are not readily available in nature need to be introduced. Researchers usually turn to fluorinated materials t...

  16. Designing Superoleophobic Surfaces (Postprint)

    Science.gov (United States)

    2007-12-07

    recent experiments show that even the wax on the lotus leaf surface is weakly hydrophilic with q ≈ 74° (29). The superhydrophobic state of these...fibers (14), and spherical arrays of poly(tetrafluoroethylene) ( PTFE ) particles (17), as well as superhydrophobicity obtained on a hydrophilic substrate

  17. Designing durable icephobic surfaces.

    Science.gov (United States)

    Golovin, Kevin; Kobaku, Sai P R; Lee, Duck Hyun; DiLoreto, Edward T; Mabry, Joseph M; Tuteja, Anish

    2016-03-01

    Ice accretion has a negative impact on critical infrastructure, as well as a range of commercial and residential activities. Icephobic surfaces are defined by an ice adhesion strength τice deicing cycles, thermal cycling, accelerated corrosion, and exposure to Michigan wintery conditions over several months.

  18. jQuery for designers beginner's guide

    CERN Document Server

    MacLees, Natalie

    2014-01-01

    A step-by-step guide that spices up your web pages and designs them in the way you want using the most widely used JavaScript library, jQuery. The beginner-friendly and easy-to-understand approach of the book will help get to grips with jQuery in no time. If you know the fundamentals of HTML and CSS, and want to extend your knowledge by learning to use JavaScript, then this is just the book for you. jQuery makes JavaScript straightforward and approachable - you'll be surprised at how easy it can be to add animations and special effects to your beautifully designed pages.

  19. ALS beamline design requirements: A guide for beamline designers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This manual is written as a guide for researchers in designing beamlines and endstations acceptable for use at the ALS. It contains guidelines and policies related to personnel safety and equipment and vacuum protection. All equipment and procedures must ultimately satisfy the safety requirements set aside in the Lawrence Berkeley National Laboratory (LBNL) Health and Safety Manual (PUB-3000) which is available from the ALS User Office or on the World WideWeb from the LBNL Homepage (http:// www.lbl.gov).

  20. Geometry of surfaces a practical guide for mechanical engineers

    CERN Document Server

    Radzevich, Stephen P

    2012-01-01

    Presents an in-depth analysis of geometry of part surfaces and provides the tools for solving complex engineering problems Geometry of Surfaces: A Practical Guide for Mechanical Engineers is a comprehensive guide to applied geometry of surfaces with focus on practical applications in various areas of mechanical engineering. The book is divided into three parts on Part Surfaces, Geometry of Contact of Part Surfaces and Mapping of the Contacting Part Surfaces. Geometry of Surfaces: A Practical Guide for Mechanical Engineers combines differential geometry and gearing theory and presents new developments in the elementary theory of enveloping surfaces. Written by a leading expert of the field, this book also provides the reader with the tools for solving complex engineering problems in the field of mechanical engineering. Presents an in-depth analysis of geometry of part surfaces Provides tools for solving complex engineering problems in the field of mechanical engineering Combines differential geometry an...

  1. Advanced Energy Design Guide for Small Hospitals and Healthcare Facilities

    Directory of Open Access Journals (Sweden)

    Eric Bonnema

    2010-01-01

    Full Text Available The Advanced Energy Design Guide for Small Hospitals and Healthcare Facilities (AEDG-SHC was recently completed. It is the sixth document in a series of guides designed to achieve 30% savings over the minimum code requirements of ANSI/ASHRAE/IESNA Standard 90.1-1999. The guide [1] is available for print purchase or as a free download from http://www.ashrae.org/aedg and provides user-friendly assistance and recommendations for the building design, construction, and owner communities to achieve energy savings. Included in the guide are prescriptive recommendations for quality assurance and commissioning; design of the building envelope; fenestration; lighting systems (including electric lighting and daylighting; heating, ventilation, and air-conditioning (HVAC systems; building automation and controls; outside air (OA treatment; and service water heating (SWH. The guide educates, provides practical recommendations for exceeding code minimums, and provides leadership to help design teams and owners produce higher efficiency commercial buildings.

  2. Antibacterial surface design - Contact kill

    Science.gov (United States)

    Kaur, Rajbir; Liu, Song

    2016-08-01

    Designing antibacterial surfaces has become extremely important to minimize Healthcare Associated Infections which are a major cause of mortality worldwide. A previous biocide-releasing approach is based on leaching of encapsulated biocides such as silver and triclosan which exerts negative impacts on the environment and potentially contributes to the development of bacterial resistance. This drawback of leachable compounds led to the shift of interest towards a more sustainable and environmentally friendly approach: contact-killing surfaces. Biocides that can be bound onto surfaces to give the substrates contact-active antibacterial activity include quaternary ammonium compounds (QACs), quaternary phosphoniums (QPs), carbon nanotubes, antibacterial peptides, and N-chloramines. Among the above, QACs and N-chloramines are the most researched contact-active biocides. We review the engineering of contact-active surfaces using QACs or N-chloramines, the modes of actions as well as the test methods. The charge-density threshold of cationic surfaces for desired antibacterial efficacy and attempts to combine various biocides for the generation of new contact-active surfaces are discussed in detail. Surface positive charge density is identified as a key parameter to define antibacterial efficacy. We expect that this research field will continue to attract more research interest in view of the potential impact of self-disinfective surfaces on healthcare-associated infections, food safety and corrosion/fouling resistance required on industrial surfaces such as oil pipes and ship hulls.

  3. Analog circuit design a tutorial guide to applications and solutions

    CERN Document Server

    Williams, Jim

    2011-01-01

    * Covers the fundamentals of linear/analog circuit and system design to guide engineers with their design challenges. * Based on the Application Notes of Linear Technology, the foremost designer of high performance analog products, readers will gain practical insights into design techniques and practice. * Broad range of topics, including power management tutorials, switching regulator design, linear regulator design, data conversion, signal conditioning, and high frequency/RF design. * Contributors include the leading lights in analog design, Robert Dobkin, Jim Willia

  4. CORFIG- CORRECTOR SURFACE DESIGN SOFTWARE

    Science.gov (United States)

    Dantzler, A.

    1994-01-01

    Corrector Surface Design Software, CORFIG, calculates the optimum figure of a corrector surface for an optical system based on real ray traces. CORFIG generates the corrector figure in the form of a spline data point table and/or a list of polynomial coefficients. The number of spline data points as well as the number of coefficients is user specified. First, the optical system's parameters (thickness, radii of curvature, etc.) are entered. CORFIG will trace the outermost axial real ray through the uncorrected system to determine approximate radial limits for all rays. Then, several real rays are traced backwards through the system from the image to the surface that originally followed the object, within these radial limits. At this first surface, the local curvature is adjusted on a small scale to direct the rays toward the object, thus removing any accumulated aberrations. For each ray traced, this adjustment will be different, so that at the end of this process the resultant surface is made up of many local curvatures. The equations that describe these local surfaces, expressed as high order polynomials, are then solved simultaneously to yield the final surface figure, from which data points are extracted. Finally, a spline table or list of polynomial coefficients is extracted from these data points. CORFIG is intended to be used in the late stages of optical design. The system's design must have at least a good paraxial foundation. Preferably, the design should be at a stage where traditional methods of Seidel aberration correction will not bring about the required image spot size specification. CORFIG will read the system parameters of such a design and calculate the optimum figure for the first surface such that all of the original parameters remain unchanged. Depending upon the system, CORFIG can reduce the RMS image spot radius by a factor of 5 to 25. The original parameters (magnification, back focal length, etc.) are maintained because all rays upon which

  5. Introducing a New Guided Design into the Classroom.

    Science.gov (United States)

    Allen, Charles W.

    Based on a workshop presented by Charles Wales, a guided design project was developed for a junior mechanical design class at California State University-Chico. This course involves lectures on the design process and an extension of the basic mechanics of materials concepts, particularly as related to design and prevention of failure. The…

  6. Usability Testing, User-Centered Design, and LibGuides Subject Guides: A Case Study

    Science.gov (United States)

    Sonsteby, Alec; DeJonghe, Jennifer

    2013-01-01

    Usability testing has become a routine way for many libraries to ensure that their Web presence is user-friendly and accessible. At the same time, popular subject guide creation systems, such as LibGuides, decentralize Web content creation and put authorship into the hands of librarians who may not be trained in user-centered design principles. At…

  7. Active and passive beam application design guide for global application

    CERN Document Server

    Rimmer, Julian

    2015-01-01

    The Active and Passive Beam Application Design Guide is the result of collaboration by worldwide experts to give system designers a current, authoritative guide on successfully applying active and passive beam technology. Active and Passive Beam Application Design Guide provide energy-efficient methods of cooling, heating, and ventilating indoor areas, especially spaces that require individual zone control and where internal moisture loads are moderate. The systems are simple to operate, with low maintenance requirements. This book is an essential resource for consulting engineers, architects, owners, and contractors who are involved in the design, operation, and installation of these systems. Building on REHVA’s Chilled Beam Application Guidebook, this new guide provides up-to-date tools and advice for designing, commissioning, and operating chilled-beam systems to achieve a determined indoor climate, and includes examples of active and passive beam calculations and selections. Dual units (SI and I-P) are...

  8. Data-Driven Guides: Supporting Expressive Design for Information Graphics.

    Science.gov (United States)

    Kim, Nam Wook; Schweickart, Eston; Liu, Zhicheng; Dontcheva, Mira; Li, Wilmot; Popovic, Jovan; Pfister, Hanspeter

    2017-01-01

    In recent years, there is a growing need for communicating complex data in an accessible graphical form. Existing visualization creation tools support automatic visual encoding, but lack flexibility for creating custom design; on the other hand, freeform illustration tools require manual visual encoding, making the design process time-consuming and error-prone. In this paper, we present Data-Driven Guides (DDG), a technique for designing expressive information graphics in a graphic design environment. Instead of being confined by predefined templates or marks, designers can generate guides from data and use the guides to draw, place and measure custom shapes. We provide guides to encode data using three fundamental visual encoding channels: length, area, and position. Users can combine more than one guide to construct complex visual structures and map these structures to data. When underlying data is changed, we use a deformation technique to transform custom shapes using the guides as the backbone of the shapes. Our evaluation shows that data-driven guides allow users to create expressive and more accurate custom data-driven graphics.

  9. Trapping and guiding surface plasmons in curved graphene landscapes

    CERN Document Server

    Smirnova, Daria; Wang, Zheng; Kivshar, Yuri S; Khanikaev, Alexander B

    2015-01-01

    We demonstrate that graphene placed on top of structured substrates offers a novel approach for trapping and guiding surface plasmons. A monolayer graphene with a spatially varying curvature exhibits an effective trapping potential for graphene plasmons near curved areas such as bumps, humps and wells. We derive the governing equation for describing such localized channel plasmons guided by curved graphene and validate our theory by the first-principle numerical simulations. The proposed confinement mechanism enables plasmon guiding by the regions of maximal curvature, and it offers a versatile platform for manipulating light in planar landscapes. In addition, isolated deformations of graphene such as bumps are shown to support localized surface modes and resonances suggesting a new way to engineer plasmonic metasurfaces.

  10. A Guide to Curriculum Development in Design Education.

    Science.gov (United States)

    Marschalek, Douglas G.

    1995-01-01

    Presents a sequential curriculum in design education focusing on product design embodying conceptual statements to guide instruction. Discusses conceptual statements for primary, intermediate, and middle school levels. Concludes that the study of design must be an integral part of the art curriculum. (CFR)

  11. Designing for Change: Guide to Adaptive Buildings

    NARCIS (Netherlands)

    De Ridder, E.

    2012-01-01

    This "designers' manual" is made during the TIDO-course AR0531 Smart & Bioclimatic Design. The reinterpretation of the word 'building' as primarily a verb, and by so a continuous process, can lead to new dynamic designs, not having the problem of waste or demolition. This manual aims to emphasize t

  12. Designing for Change: Guide to Adaptive Buildings

    NARCIS (Netherlands)

    De Ridder, E.

    2012-01-01

    This "designers' manual" is made during the TIDO-course AR0531 Smart & Bioclimatic Design. The reinterpretation of the word 'building' as primarily a verb, and by so a continuous process, can lead to new dynamic designs, not having the problem of waste or demolition. This manual aims to emphasize t

  13. A Design Guide for Early-Market Electrochromic Windows

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eleanor S.; Selkowitz, Stephen E.; Clear, Robert D.; DiBartolomeo, Dennis L.; Klems, Joseph H.; Fernandes, Luis L.; Ward, GregJ.; Inkarojrit, Vorapat; Yazdanian, Mehry

    2006-05-01

    Switchable variable-tint electrochromic (EC) windows preserve view out while modulating transmitted light, glare, and solar heat gains. Consumers will require objective information on the risks and benefits of this emerging technology as it enters the market in 2006. This guide provides such information and data derived from a wide variety of simulations, laboratory tests, and a 2.5-year field test of prototype large-area EC windows evaluated under outdoor sun and sky conditions. This design guide is provided to architects, engineers, building owners, and others interested in electrochromic windows. The design guide provides basic information about what is an electrochromic window, what it looks like, how fast does it switch, and what current product offerings are. The guide also provides information on performance benefits if more mature product offerings were available.

  14. Designing a Resource Guide to help promote health in caregiving.

    Science.gov (United States)

    Leenerts, Mary Hobbs; Teel, Cynthia S; Shafton, Gayle

    2007-09-01

    Aim.  To describe development of a Resource Guide, one component of a theory-based intervention. The Guide contains information and ideas to illuminate caregivers' self-care knowledge as a basis for organizing and reinforcing self-care activities. Background.  Inherent in the complexity of caregiving roles is the emergence of caregiving as a responsibility, often overshadowing caregiver's personal care needs. Health care professionals can partner with caregivers to promote caregiver health. Self-Care TALK is a multimodal intervention to support this partnership. Methods.  Two theoretical perspectives guided Resource Guide content; adult learning theory and the schema model of cognitive behavioural theory. Materials to stimulate conversations about caregivers' personal concerns about self-care were adapted from extant literature. Sources of information were chosen based on caregivers' learning needs and images of health. Areas of development focused on content, reading level/readability, graphic design, and self-evaluation. Results.  The Resource Guide standardizes Self-Care TALK protocol while personalizing caregivers' self-care. The Resource Guide provides structure for conversations about what self-care is and ways to promote health. Conclusion.  The Resource Guide promotes a learning environment that complements interests and experiences of older caregivers. Use of the Guide supports and extends caregivers' self-care vocabularies, and helps clarify self-care schemas and health promotion.

  15. The designer's guide to presenting numbers, figures, and charts

    CERN Document Server

    Bigwood, Sally

    2013-01-01

    Numbers can tell an exciting story. The trick is to know what story to tell and make it understandable. This compact, practical guide will show everyone who must design numeric data how to transform raw data into readable, relevant information.The Designer's Guide to Presenting Numbers, Figures, and Charts brings together the guidelines established over the last forty years for making effective presentations of figures, tables, and graphs. Included are the straightforward steps designers and other professionals can take to make their tables and charts the most meaningful. The authors define an

  16. Leveraging design activism to guide public projects towards citizen inclusion

    DEFF Research Database (Denmark)

    Casciola, Lara; Götzen, Amalia De; Morelli, Nicola

    2017-01-01

    This paper explores a case wherein design activism was leveraged to guide the governance of a public project towards greater citizen inclusion. This exploration, part of a master’s thesis in Service Design at Aalborg university, centres on Copenhagen’s Street Lab – a living lab where technological...

  17. A design guide for energy-efficient research laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Wishner, N.; Chen, A.; Cook, L. [eds.; Bell, G.C.; Mills, E.; Sartor, D.; Avery, D.; Siminovitch, M.; Piette, M.A.

    1996-09-24

    This document--A Design Guide for Energy-Efficient Research Laboratories--provides a detailed and holistic framework to assist designers and energy managers in identifying and applying advanced energy-efficiency features in laboratory-type environments. The Guide fills an important void in the general literature and compliments existing in-depth technical manuals. Considerable information is available pertaining to overall laboratory design issues, but no single document focuses comprehensively on energy issues in these highly specialized environments. Furthermore, practitioners may utilize many antiquated rules of thumb, which often inadvertently cause energy inefficiency. The Guide helps its user to: introduce energy decision-making into the earliest phases of the design process, access the literature of pertinent issues, and become aware of debates and issues on related topics. The Guide does focus on individual technologies, as well as control systems, and important operational factors such as building commissioning. However, most importantly, the Guide is intended to foster a systems perspective (e.g. right sizing) and to present current leading-edge, energy-efficient design practices and principles.

  18. Learning design guided learning analytics in MOOCs

    NARCIS (Netherlands)

    Brouns, Francis; Firssova, Olga

    2016-01-01

    Poster presentation for our paper Brouns, F., & Firssova, O. (2016, October).The role of learning design and learning analytics in MOOCs. Paper presented at 9th EDEN Research Workshop, Oldenburg, Germany.

  19. Learning design guided learning analytics in MOOCs

    NARCIS (Netherlands)

    Brouns, Francis; Firssova, Olga

    2016-01-01

    Poster presentation for our paper Brouns, F., & Firssova, O. (2016, October).The role of learning design and learning analytics in MOOCs. Paper presented at 9th EDEN Research Workshop, Oldenburg, Germany.

  20. Guiding bioprocess design by microbial ecology.

    Science.gov (United States)

    Volmer, Jan; Schmid, Andreas; Bühler, Bruno

    2015-06-01

    Industrial bioprocess development is driven by profitability and eco-efficiency. It profits from an early stage definition of process and biocatalyst design objectives. Microbial bioprocess environments can be considered as synthetic technical microbial ecosystems. Natural systems follow Darwinian evolution principles aiming at survival and reproduction. Technical systems objectives are eco-efficiency, productivity, and profitable production. Deciphering technical microbial ecology reveals differences and similarities of natural and technical systems objectives, which are discussed in this review in view of biocatalyst and process design and engineering strategies. Strategies for handling opposing objectives of natural and technical systems and for exploiting and engineering natural properties of microorganisms for technical systems are reviewed based on examples. This illustrates the relevance of considering microbial ecology for bioprocess design and the potential for exploitation by synthetic biology strategies.

  1. DOT-7A Type A packaging design guide

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, D.L.

    1995-01-23

    The purpose of this Design Guide is to provide instruction for designing a U.S. Department of Transportation Specification 7A (DOT-7A) Type A packaging. Another purpose for this Design Guide is to support the evaluation and testing activities that are performed on new designs by a U.S. Department of Energy (DOE) test facility. This evaluation and testing program is called the DOT-7A Program. When an applicant has determined that a DOT-7A packaging is needed and not commercially available, a design may be created according to this document. The design should include a packaging drawing, specifications, analysis report, operating instructions, and a Packaging Qualification Checklist; all of which should be forwarded to a DOE/HQ approved test facility for evaluation and testing. This report is being submitted through the Engineering Documentation System so that it may be used for reference and information purposes.

  2. Design of Optical Microscopes Some Guiding Factors

    Directory of Open Access Journals (Sweden)

    S. P. Roy

    1969-04-01

    Full Text Available The essential parameters of different types of microscopes, e.g.. magnification, resolving power and numerical aperture, have been highlighted and relations among these parameters have been established. Effort has been made to correlate focal length and numerical aperture of objectives, which may prove useful to the microscope designers in the country.

  3. CAM and stack air sampler design guide

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, T.D.

    1994-05-13

    About 128 air samplers and CAMs presently in service to detect and document potential radioactive release from `H` and `F` area tank farm ventilation stacks are scheduled for replacement and/or upgrade by Projects S-5764, S-2081, S-3603, and S-4516. The seven CAMs scheduled to be upgraded by Project S-4516 during 1995 are expected to provide valuable experience for the three remaining projects. The attached document provides design guidance for the standardized High Level Waste air sampling system.

  4. High Voltage Design Guide. Volume V. Spacecraft

    Science.gov (United States)

    1983-01-01

    connector are soldered, with the possible exception of very high voltage points. Even then rudimentary connectors such as that shown In figura 13 ar used...addition, large stresses will be imposed on the struc- tural (high resistance) member. This conductor movement will flex and stretch the conductors, placing...materials used for airplane systems provided they meet the electrical, chemical, and mechanical characteristic requirements imposed by the design

  5. The designer's guide to Verilog-AMS

    CERN Document Server

    Kundert, Kenneth S

    2004-01-01

    The Verilog Hardware Description Language (Verilog-HDL) has long been the most popular language for describing complex digital hardware. It started life as a prop- etary language but was donated by Cadence Design Systems to the design community to serve as the basis of an open standard. That standard was formalized in 1995 by the IEEE in standard 1364-1995. About that same time a group named Analog Verilog International formed with the intent of proposing extensions to Verilog to support analog and mixed-signal simulation. The first fruits of the labor of that group became available in 1996 when the language definition of Verilog-A was released. Verilog-A was not intended to work directly with Verilog-HDL. Rather it was a language with Similar syntax and related semantics that was intended to model analog systems and be compatible with SPICE-class circuit simulation engines. The first implementation of Verilog-A soon followed: a version from Cadence that ran on their Spectre circuit simulator. As more impleme...

  6. Signage and wayfinding design a complete guide to creating environmental graphic design systems

    CERN Document Server

    Calori, Chris

    2015-01-01

    A new edition of the market-leading guide to signage and wayfinding design This new edition of Signage and Wayfinding Design: A Complete Guide to Creating Environmental Graphic Design Systems has been fully updated to offer you the latest, most comprehensive coverage of the environmental design process-from research and design development to project execution. Utilizing a cross-disciplinary approach that makes the information relevant to architects, interior designers, landscape architects, graphic designers, and industrial engineers alike, the book arms you with the skills needed to apply a

  7. Regioselective patterning of multiple SAMs and applications in surface-guided smart microfluidics.

    Science.gov (United States)

    Chen, Chuanzhao; Xu, Pengcheng; Li, Xinxin

    2014-12-24

    A top-down nanofabrication technology is developed to integrate multiple SAMs (self-assembled monolayers) into regioselective patterns. With ultraviolet light exposure through regioselectively hollowed hard mask, an existing SAM at designated microregions can be removed and a dissimilar kind of SAM can be regrown there. By repeating the photolithography-like process cycle, diverse kinds of SAM building blocks can be laid out as a desired pattern in one microfluidic channel. In order to ensure high quality of the surface modifications, the SAMs are vapor-phase deposited before the channel is closed by a bonding process. For the first time the technique makes it possible to integrate three or more kinds of SAMs in one microchannel. The technique is very useful for multiplex surface functionalization of microfluidic chips where different segments of a microfluidic channel need to be individually modified with different SAMs or into arrayed pattern for surface-guided fluidic properties like hydrophobicity/philicity and/or oleophobicity/philicity, etc. The technique has been well validated by experimental demonstration of various surface-directed flow-guiding functions. By modifying a microchannel surface into an arrayed pattern of multi-SAM "two-tone" stripe array, surface-guiding-induced 3D swirling flow is generated in a microfluidic channel that experimentally exhibits quick oil/water mixing and high-efficiency oil-to-water chemical extraction.

  8. Proven procedures guide cavity VCO design

    Science.gov (United States)

    Lefrak, F.

    1981-05-01

    The design of a high performance voltage-tuned cavity oscillator is discussed. The circuit is to be modeled with an equivalent inductance and capacitance. Close attention is to be given to the influence of cavity loading. Center frequency and impedance are computed on the basis of the model's L and C values. The last step is particularly important, since the size of a cavity-based oscillator, such as the Gunn/varactor version is directly related to operating frequency. Attention is given to the parallel L-C circuit representing the cavity, parameter relations concerning the height, higher-order TE modes, and effects of post inductance. The basic oscillator consists of a hollow cavity with metal walls, and diodes mounted on posts.

  9. Best Practices Guide for Energy-Efficient Data Center Design

    Energy Technology Data Exchange (ETDEWEB)

    O. VanGeet: NREL

    2010-02-24

    This guide provides an overview of best practices for energy-efficient data center design which spans the categories of Information Technology (IT) systems and their environmental conditions, data center air management, cooling and electrical systems, on-site generation, and heat recovery.

  10. Study Design and Data Gathering Guide for Serious Games’ Evaluation

    NARCIS (Netherlands)

    Baalsrud Hauge, Jannicke; Boyle, Elizabeth; Mayer, Igor; Nadolski, Rob; Riedel, Johann C. K. H.; Moreno-Ger, Pablo; Bellotti, Francesco; Lim, Theodore; Ritchie, James

    2013-01-01

    Baalsrud Hauge, J., Boyle, E., Mayer, I., Nadolski, R. J., Riedel, J. C. K. H., Moreno-Ger, P., Bellotti, F., Lim, T., & Ritchie, J. (2013). Study Design and Data Gathering Guide for Serious Games’ Evaluation. In T. M. Connolly, T. Hainey, E. Boyle, G. Baxter, & P. Moreno-Ger (Eds.), Psychology,

  11. Field Guide for Designing Human Interaction with Intelligent Systems

    Science.gov (United States)

    Malin, Jane T.; Thronesbery, Carroll G.

    1998-01-01

    The characteristics of this Field Guide approach address the problems of designing innovative software to support user tasks. The requirements for novel software are difficult to specify a priori, because there is not sufficient understanding of how the users' tasks should be supported, and there are not obvious pre-existing design solutions. When the design team is in unfamiliar territory, care must be taken to avoid rushing into detailed design, requirements specification, or implementation of the wrong product. The challenge is to get the right design and requirements in an efficient, cost-effective manner. This document's purpose is to describe the methods we are using to design human interactions with intelligent systems which support Space Shuttle flight controllers in the Mission Control Center at NASA/Johnson Space Center. Although these software systems usually have some intelligent features, the design challenges arise primarily from the innovation needed in the software design. While these methods are tailored to our specific context, they should be extensible, and helpful to designers of human interaction with other types of automated systems. We review the unique features of this context so that you can determine how to apply these methods to your project Throughout this Field Guide, goals of the design methods are discussed. This should help designers understand how a specific method might need to be adapted to the project at hand.

  12. Distinctive Design A Practical Guide to a Useful, Beautiful Web

    CERN Document Server

    Dawson, Alexander

    2011-01-01

    Learn to produce a web site that stands out from the crowd One of the web designer's greatest challenges is to create a site distinctive enough to get noticed among the millions of sites already on the web. This book examines the bond between code, content and visuals to guide you through the factors that increase your design's visibility, usability and beauty. Using this practical advice, even web designers who lack strong artistic skills can develop super sites that strengthen the message and stand out from the crowd.Most books focus primarily on graphic design principles; this one shows you

  13. SNL Mechanical Computer Aided Design (MCAD) guide 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Brandon; Pollice, Stephanie L.; Martinez, Jack R.

    2007-12-01

    This document is considered a mechanical design best-practice guide to new and experienced designers alike. The contents consist of topics related to using Computer Aided Design (CAD) software, performing basic analyses, and using configuration management. The details specific to a particular topic have been leveraged against existing Product Realization Standard (PRS) and Technical Business Practice (TBP) requirements while maintaining alignment with sound engineering and design practices. This document is to be considered dynamic in that subsequent updates will be reflected in the main title, and each update will be published on an annual basis.

  14. Knots and surfaces a guide to discovering mathematics

    CERN Document Server

    Farmer, David W

    1995-01-01

    In most mathematics textbooks, the most exciting part of mathematics-the process of invention and discovery-is completely hidden from the reader. The aim of Knots and Surfaces is to change all that. By means of a series of carefully selected tasks, this book leads readers to discover some real mathematics. There are no formulas to memorize; no procedures to follow. The book is a guide: its job is to start you in the right direction and to bring you back if you stray too far. Discovery is left to you. Suitable for a one-semester course at the beginning undergraduate level, there are no prerequi

  15. Light waves guided by a single curved metallic surface.

    Science.gov (United States)

    Krammer, H

    1978-01-15

    Propagation of TE-waves along a single curved metallic surface with radius of curvature much larger than wavelength is investigated both theoretically and experimentally. Approximate analytic expressions for the field configuration yield that power concentrates in a small region near the metal. The attenuation constant per unit angle of bend (radian) is given by the real part of the inverse of the refractive index, independent of the radius of curvature and of the mode number. In agreement with theory experiments with 10-microm radiation showed that low loss guiding can be realized.

  16. Designing and conducting survey research a comprehensive guide

    CERN Document Server

    Rea, Louis M

    2014-01-01

    The industry standard guide, updated with new ideas and SPSS analysis techniques Designing and Conducting Survey Research: A Comprehensive Guide Fourth Edition is the industry standard resource that covers all major components of the survey process, updated to include new data analysis techniques and SPSS procedures with sample data sets online. The book offers practical, actionable guidance on constructing the instrument, administrating the process, and analyzing and reporting the results, providing extensive examples and worksheets that demonstrate the appropriate use of survey and data tech

  17. Robust topology design of periodic grating surfaces

    DEFF Research Database (Denmark)

    Friis, Kasper Storgaard; Sigmund, Ole

    2012-01-01

    Modern nanoscale manufacturing techniques allow for a high degree of flexibility in designing surface microstructures and nanostructures. Injection molding of nanosized features allows for mass production of plastic components with a tailored nanostructure producing specific optical effects...... depending on the purpose. This work details the use of topology optimization for designing periodic polymer grating surfaces with complex optical properties. A method based on robust topology optimization is formulated for designing the nanostructure of plastic surfaces with extreme reflection...

  18. Guided shear horizontal surface acoustic wave sensors for chemical and biochemical detection in liquids.

    Science.gov (United States)

    Josse, F; Bender, F; Cernose, R W

    2001-12-15

    The design and performance of guided shear horizontal surface acoustic wave (guided SH-SAW) devices on LiTaO3 substrates are investigated for high-sensitivity chemical and biochemical sensors in liquids. Despite their structural similarity to Rayleigh SAW, SH-SAWs often propagate slightly deeper within the substrate, hence preventing the implementation of high-sensitivity detectors. The device sensitivity to mass and viscoelastic loading is increased using a thin guiding layer on the device surface. Because of their relatively low shear wave velocity, various polymers including poly(methyl methacrylate) (PMMA) and cyanoethyl cellulose (cured or cross-linked) are investigated as the guiding layers to trap the acoustic energy near the sensing surface. The devices have been tested in biosensing and chemical sensing experiments. Suitable design principles for these applications are discussed with regard to wave guidance, electrical passivation of the interdigital transducers from the liquid environments, acoustic loss, and sensor signal distortion. In biosensing experiments, using near-optimal PMMA thickness of approximately 2 microm, mass sensitivity greater than 1500 Hz/(ng/mm2) is demonstrated, resulting in a minimum detection limit less than 20 pg/mm2. For chemical sensor experiments, it is found that optimal waveguide thickness must be modified to account for the chemically sensitive layer which also acts to guide the SH-SAW. A detection limit of 780 (3 x peak-to-peak noise) or 180 ppb (3 x rms noise) is estimated from the present measurements for some organic compounds in water.

  19. The Ibaraki prefecture materials design diffractometer for J-PARC—Designing neutron guide

    Science.gov (United States)

    Harjo, Stefanus; Kamiyama, Takashi; Torii, Shuki; Ishigaki, Toru; Yonemura, Masao

    2006-11-01

    Ibaraki prefecture materials design diffractometer of J-PARC needs a neutron guide to increase beam intensity without sacrificing measurements of powder diffraction with good resolution, PDF analysis and small angle scattering. Non-parallel guides including elliptical ones have been compared with a linear-straight guide using the McStas simulation. The elliptical guide having the exit focal points away behind the sample position is available to increase the neutron flux at the sample but gives a slight lowering of the instrumental resolution. This elliptical guide gives also Garland peaks at short wavelengths that may give large ambiguities in powder diffraction measurements. Therefore, the linear-straight guide is considered as the best choice for this instrument to keep a good resolution and also a relatively high flux.

  20. The Ibaraki prefecture materials design diffractometer for J-PARC-Designing neutron guide

    Energy Technology Data Exchange (ETDEWEB)

    Harjo, Stefanus [Quantum Beam Science Directorate, Japan Atomic Energy Agency, Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan)]. E-mail: harjo.stefanus@jaea.go.jp; Kamiyama, Takashi [Institute of Materials Structure Science, High Energy Accelerator Research Organization, 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Torii, Shuki [Quantum Beam Science Directorate, Japan Atomic Energy Agency, Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan); Ishigaki, Toru [Quantum Beam Science Directorate, Japan Atomic Energy Agency, Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan); Yonemura, Masao [Institute of Applied Beam Science, Graduate School of Science and Engineering, Ibaraki University, 4-12-1 Nakanarusawa, Hitachi, Ibaraki 316-8511 (Japan)

    2006-11-15

    Ibaraki prefecture materials design diffractometer of J-PARC needs a neutron guide to increase beam intensity without sacrificing measurements of powder diffraction with good resolution, PDF analysis and small angle scattering. Non-parallel guides including elliptical ones have been compared with a linear-straight guide using the McStas simulation. The elliptical guide having the exit focal points away behind the sample position is available to increase the neutron flux at the sample but gives a slight lowering of the instrumental resolution. This elliptical guide gives also Garland peaks at short wavelengths that may give large ambiguities in powder diffraction measurements. Therefore, the linear-straight guide is considered as the best choice for this instrument to keep a good resolution and also a relatively high flux.

  1. GIS cartography a guide to effective map design

    CERN Document Server

    Peterson, Gretchen N

    2009-01-01

    Maps, either printed or digital, can create effective communication with bosses, clients, other scientists, and the public. However, entry level GISers often find that map design was given short shrift in their pre-professional life. It is time for the GIS field, which is maturing in other ways, to improve its skills in this area. Based on the author's more than ten years of research and practice in map design, GIS Cartography: A Guide to Effective Map Design provides the tools to create truly sophisticated maps. Packed full of in-depth information and advice, this book covers all facets of ma

  2. CMOS sigma-delta converters practical design guide

    CERN Document Server

    De la Rosa, Jose M

    2013-01-01

    A comprehensive overview of Sigma-Delta Analog-to-Digital Converters (ADCs) and a practical guide to their design in nano-scale CMOS for optimal performance. This book presents a systematic and comprehensive compilation of sigma-delta converter operating principles, the new advances in architectures and circuits, design methodologies and practical considerations - going from system-level specifications to silicon integration, packaging and measurements, with emphasis on nanometer CMOS implementation. The book emphasizes practical design issues - from high-level behavioural modelling i

  3. Standard guide for general design considerations for hot cell equipment

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2008-01-01

    1.1 Intent: 1.1.1 The intent of this guide is to provide general design and operating considerations for the safe and dependable operation of remotely operated hot cell equipment. Hot cell equipment is hardware used to handle, process, or analyze nuclear or radioactive material in a shielded room. The equipment is placed behind radiation shield walls and cannot be directly accessed by the operators or by maintenance personnel because of the radiation exposure hazards. Therefore, the equipment is operated remotely, either with or without the aid of viewing. 1.1.2 This guide may apply to equipment in other radioactive remotely operated facilities such as suited entry repair areas, canyons or caves, but does not apply to equipment used in commercial power reactors. 1.1.3 This guide does not apply to equipment used in gloveboxes. 1.2 Applicability: 1.2.1 This guide is intended for persons who are tasked with the planning, design, procurement, fabrication, installation, or testing of equipment used in rem...

  4. A design guide and specification for small explosive containment structures

    Energy Technology Data Exchange (ETDEWEB)

    Marchand, K.A.; Cox, P.A.; Polcyn, M.A. [Southwest Research Institute, San Antonio, TX (United States)

    1994-12-01

    The design of structural containments for testing small explosive devices requires the designer to consider the various aspects of the explosive loading, i.e., shock and gas or quasistatic pressure. Additionally, if the explosive charge has the potential of producing damaging fragments, provisions must be made to arrest the fragments. This may require that the explosive be packed in a fragment attenuating material, which also will affect the loads predicted for containment response. Material also may be added just to attenuate shock, in the absence of fragments. Three charge weights are used in the design. The actual charge is used to determine a design fragment. Blast loads are determined for a {open_quotes}design charge{close_quotes}, defined as 125% of the operational charge in the explosive device. No yielding is permitted at the design charge weight. Blast loads are also determined for an over-charge, defined as 200% of the operational charge in the explosive device. Yielding, but no failure, is permitted at this over-charge. This guide emphasizes the calculation of loads and fragments for which the containment must be designed. The designer has the option of using simplified or complex design-analysis methods. Examples in the guide use readily available single degree-of-freedom (sdof) methods, plus static methods for equivalent dynamic loads. These are the common methods for blast resistant design. Some discussion of more complex methods is included. Generally, the designer who chooses more complex methods must be fully knowledgeable in their use and limitations. Finally, newly fabricated containments initially must be proof tested to 125% of the operational load and then inspected at regular intervals. This specification provides guidance for design, proof testing, and inspection of small explosive containment structures.

  5. Guide to object-oriented analysis and design

    Science.gov (United States)

    Harrison, Harry C.

    1992-01-01

    The purpose of this guide is to provide Marshall Space Flight Center personnel with guidelines for the use of object-oriented analysis and design and to describe how it can be accomplished within the framework of existing development directives, including the Software Development Plan. It is not intended as a detailed tutorial. The reader is referred to the Coad and Yourdon texts in the References.

  6. 2016 U.S. Department of Energy Race to Zero Student Design Competition Guide

    Energy Technology Data Exchange (ETDEWEB)

    2016-03-01

    This Guide to the Race to Zero Student Design Competition is a comprehensive overview of the framework, timeline, design parameters, judging criteria, and awards. This Guide provides links to resources that the teams will need.

  7. Unidirectional propagation of designer surface acoustic waves

    CERN Document Server

    Lu, Jiuyang; Ke, Manzhu; Liu, Zhengyou

    2014-01-01

    We propose an efficient design route to generate unidirectional propagation of the designer surface acoustic waves. The whole system consists of a periodically corrugated rigid plate combining with a pair of asymmetric narrow slits. The directionality of the structure-induced surface waves stems from the destructive interference between the evanescent waves emitted from the double slits. The theoretical prediction is validated well by simulations and experiments. Promising applications can be anticipated, such as in designing compact acoustic circuits.

  8. Biological decontamination of surfaces using guided ionization waves

    Science.gov (United States)

    Jarrige, Julien; Zaepffel, Clement

    2016-09-01

    Atmospheric pressure plasma jets have received an increasing attention these last ten years in various domains, including biomedical applications and decontamination. Among these technologies, guided ionization waves (also called ``plasma bullets'') are very promising because of their ability to produce a highly non-equilibrium plasma. Reactive species can be generated in the open air over a long distance during the propagation of the wave (typically: several cm), while the background gas remains at ambient temperature. A non-thermal plasma system has been developed and tested for the biological decontamination of surfaces. It consists of a dielectric barrier discharge in a helium flow driven by high voltage pulses. The propagation of the ionization wave and the spatial distribution of the species have been characterized by high speed imaging and optical emission spectroscopy. The influence of the discharge parameters on the plasma properties is investigated. Results of decontamination on several bacteria are shown, and the decontamination efficiency is compared with the plasma properties.

  9. Light-Guided Surface Engineering for Biomedical Applications

    Science.gov (United States)

    Jayagopal, Ashwath; Stone, Gregory P.; Haselton, Frederick R.

    2010-01-01

    Free radical species generated through fluorescence photobleaching have been reported to effectively couple a water-soluble species to surfaces containing electron-rich sites (1). In this report, we expand upon this strategy to control the patterned attachment of antibodies and peptides to surfaces for biosensing and tissue engineering applications. In the first application, we compare hydrophobic attachment and photobleaching methods to immobilize FITC-labeled anti-M13K07 bacteriophage antibodies to the SiO2 layer of a differential capacitive biosensor and to the polyester filament of a feedback-controlled filament array. On both surfaces, antibody attachment and function were superior to the previously employed hydrophobic attachment. Furthermore, a laser scanning confocal microscope could be used for automated, software-guided photoattachment chemistry. In a second application, the cell-adhesion peptide RGDS was site-specifically photocoupled to glass coated with fluorescein-conjugated poly(ethylene glycol). RGDS attachment and bioactivity were characterized by a fibroblast adhesion assay. Cell adhesion was limited to sites of RGDS photocoupling. These examples illustrate that fluorophore-based photopatterning can be achieved by both solution-phase fluorophores or surface-adhered fluorophores. The coupling preserves the bioactivity of the patterned species, is amenable to a variety of surfaces, and is readily accessible to laboratories with fluorescence imaging equipment. The flexibility offered by visible light patterning will likely have many useful applications in bioscreening and tissue engineering where the controlled placement of biomolecules and cells is critical, and should be considered as an alternative to chemical coupling methods. PMID:18314938

  10. Designing visual appearance using a structured surface

    DEFF Research Database (Denmark)

    Johansen, Villads Egede; Thamdrup, Lasse Højlund; Smitrup, Christian;

    2015-01-01

    We present an approach for designing nanostructured surfaces with prescribed visual appearances, starting at design analysis and ending with a fabricated sample. The method is applied to a silicon wafer structured using deep ultraviolet lithography and dry etching and includes preliminary design ...

  11. Standard guide for design criteria for plutonium gloveboxes

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This guide defines criteria for the design of glovebox systems to be used for the handling of plutonium in any chemical or physical form or isotopic composition or when mixed with other elements or compounds. Not included in the criteria are systems auxiliary to the glovebox systems such as utilities, ventilation, alarm, and waste disposal. Also not addressed are hot cells or open-face hoods. The scope of this guide excludes specific license requirements relating to provisions for criticality prevention, hazards control, safeguards, packaging, and material handling. Observance of this guide does not relieve the user of the obligation to conform to all federal, state, and local regulations for design and construction of glovebox systems. 1.2 The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only. 1.3 This standard does not purport to address all of the safety problems, if any, associated with its use. It is the responsibility of the user...

  12. Alarm systems a guide to design, management and procurement

    CERN Document Server

    Engineering Equipment and Materials Users' Association. London

    2013-01-01

    Alarm systems form an essential part of the operator interfaces to large modern industrial facilities. They provide vital support to the operators by warning them of situations that need their attention and have an important role in preventing, controlling and mitigating the effects of abnormal situations. Since it was first published in 1999, EEMUA 191 has become the globally accepted and leading guide to good practice for all aspects of alarm systems. The guide, developed by users of alarm systems with input from the GB Health and Safety Executive, gives comprehensive guidance on designing, managing and procuring an effective alarm system. The new Third Edition has been comprehensively updated and includes guidance on implementing the alarm management philosophy in practice; applications in geographically distributed processes; and performance metrics and KPIs.

  13. Optimal design of a piezoelectric transducer for exciting guided wave ultrasound in rails

    Science.gov (United States)

    Ramatlo, Dineo A.; Wilke, Daniel N.; Loveday, Philip W.

    2017-02-01

    An existing Ultrasonic Broken Rail Detection System installed in South Africa on a heavy duty railway line is currently being upgraded to include defect detection and location. To accomplish this, an ultrasonic piezoelectric transducer to strongly excite a guided wave mode with energy concentrated in the web (web mode) of a rail is required. A previous study demonstrated that the recently developed SAFE-3D (Semi-Analytical Finite Element - 3 Dimensional) method can effectively predict the guided waves excited by a resonant piezoelectric transducer. In this study, the SAFE-3D model is used in the design optimization of a rail web transducer. A bound-constrained optimization problem was formulated to maximize the energy transmitted by the transducer in the web mode when driven by a pre-defined excitation signal. Dimensions of the transducer components were selected as the three design variables. A Latin hypercube sampled design of experiments that required a total of 500 SAFE-3D analyses in the design space was employed in a response surface-based optimization approach. The Nelder-Mead optimization algorithm was then used to find an optimal transducer design on the constructed response surface. The radial basis function response surface was first verified by comparing a number of predicted responses against the computed SAFE-3D responses. The performance of the optimal transducer predicted by the optimization algorithm on the response surface was also verified to be sufficiently accurate using SAFE-3D. The computational advantages of SAFE-3D in optimal transducer design are noteworthy as more than 500 analyses were performed. The optimal design was then manufactured and experimental measurements were used to validate the predicted performance. The adopted design method has demonstrated the capability to automate the design of transducers for a particular rail cross-section and frequency range.

  14. Design and Use of a Guided Weight Impactor to Impart Barely Visible Impact Damage

    Science.gov (United States)

    Lovejoy, Andrew E.; Przekop, Adam

    2016-01-01

    Aircraft structure is required to demonstrate satisfaction of the FAR requirements for Category 1, such as barely visible impact damage (BVID). Typical aircraft structure is impacted using a dropped weight impactor, which can impart BVID to the top surface of the structure. A recent test of a multi-bay box (MBB) composite test article, that represents an 80% scale center section of a hybrid wing body aircraft, required impact to be in a direction other than vertical from above, but still in an direction that is normal to the surface. This requirement eliminated the use of the conventional dropped weight impactor. Therefore, a design study was undertaken to determine the most effective way to efficiently and reliably impact the MBB. The chosen design was a guided weight impactor that is gravity driven. This paper describes the design of the guided weight impactor, and presents the results of its use for imparting BVID to the MBB. The guided weight impactor was seen to be a very reliable method to impart BVID, while at the same time having the capability to be highly configurable for use on other aircraft structure that is impacted at a variety of impact energies and from a variety of directions.

  15. Becoming a Digital Designer A Guide to Careers in Web, Video, Broadcast, Game and Animation Design

    CERN Document Server

    Heller, Steven

    2011-01-01

    From the author of the bestselling Becoming a Graphic Designer and the editor of Adobe Think Tank comes this clear overview of the field of digital design This complete guide to the evolving digital design disciplines opens the door to today's most sought-after job opportunities in Web, video, broadcast, game, and animation design. Featuring over 45 interviews with leading digital designers and more than 225 illustrations, the book covers everything from education and training, design specialties, and work settings to preparing an effective portfolio and finding a job. This is an ideal startin

  16. Socio-technical Spaces: Guiding Politics, Staging Design

    DEFF Research Database (Denmark)

    Clausen, Christian; Yoshinaka, Yutaka

    2005-01-01

    This article addresses how insights from the social shaping tradition and political process theory may contribute to an understanding of the sociotechnical design and implementation of change. This idea is pursued through the notion of 'socio-technical spaces' and its delineation, with respect...... to the role of socio-material and discursive practices in rendering spaces open to problematisation and action. It is suggested that the notion of socio-technical spaces helps generate a sensitising guide for researchers and practitioners, and is proposed as a constructive means to localising potential...

  17. Going viral: designing bioactive surfaces with bacteriophage.

    Science.gov (United States)

    Hosseinidoust, Zeinab; Olsson, Adam L J; Tufenkji, Nathalie

    2014-12-01

    Bacteriophage-functionalized bioactive surfaces are functional materials that can be used as antimicrobial surfaces in medical applications (e.g., indwelling medical devices or wound dressings) or as biosensors for bacterial capture and detection. Despite offering immense potential, designing efficient phage-functionalized bioactive surfaces is hampered by a number of challenges. This review offers an overview of the current state of knowledge in this field and presents a critical perspective of the technological promises and challenges.

  18. [Research development of surface hydrophilicity and lubrication modification of interventional guide wire].

    Science.gov (United States)

    Zhao, Bing; Liu, Xiaohong; Yuan, Ting

    2015-01-01

    Surface lubricity is one of the important performance criteria for interventional guide wire. In this paper, a review of the methods of surface hydrophilicity and lubrication modification of interventional guide wire is presented, including their fundamental principles, effects and some relative applications. These methods all have their own advantages and disadvantages, therefore, limitations of experimental conditions need to be taken into account.

  19. USE OF SURFACE GUIDE PANELS AS PIER SCOUR COUNTERMEASURES

    Institute of Scientific and Technical Information of China (English)

    Chin-Kun HUANG; Chii-Jau TANG; Ting-Yuan KUO

    2005-01-01

    This paper presents a laboratory study on bridge pier protection with surface guide panels (SGP) in clear-water experiments. The SGP is installed by piercing a set of two vertical panels partially into the water, with some interior angle and leading opening, setting at a distance ahead of the protected pier. The suitable installation of the SGP can effectively adjust the flow pattern to reduce the downflow motion and the horseshoe vortex ahead of the pier. We consider some dominant factors to set up SGP for pier protection, including the interior angle θ, leading opening Ow, distance between panel and pier L, submerged depth of panel Pd, pier diameter D and water depth H. After evaluation of these parameters through laboratory tests, the optimal setup conditions of θ=60o, Ow/D=0.1~0.2, L/D=2~2.5 and Pd/H=0.7 are determined. Under these conditions, the usage of SGP leads to a best performance on decrement of the maximum scour depth at pier up to 90% with ignorable side effects on the SGP scour.

  20. Guided Wave Annular Array Sensor Design for Improved Tomographic Imaging

    Science.gov (United States)

    Koduru, Jaya Prakash; Rose, Joseph L.

    2009-03-01

    Guided wave tomography for structural health monitoring is fast emerging as a reliable tool for the detection and monitoring of hotspots in a structure, for any defects arising from corrosion, crack growth etc. To date guided wave tomography has been successfully tested on aircraft wings, pipes, pipe elbows, and weld joints. Structures practically deployed are subjected to harsh environments like exposure to rain, changes in temperature and humidity. A reliable tomography system should take into account these environmental factors to avoid false alarms. The lack of mode control with piezoceramic disk sensors makes it very sensitive to traces of water leading to false alarms. In this study we explore the design of annular array sensors to provide mode control for improved structural tomography, in particular, addressing the false alarm potential of water loading. Clearly defined actuation lines in the phase velocity dispersion curve space are calculated. A dominant in-plane displacement point is found to provide a solution to the water loading problem. The improvement in the tomographic images with the annular array sensors in the presence of water traces is clearly illustrated with a series of experiments. An annular array design philosophy for other problems in NDE/SHM is also discussed.

  1. Designing coupled free-form surfaces.

    Science.gov (United States)

    Hicks, R Andrew; Croke, Christopher

    2010-10-01

    The problem of designing optical systems that contain free-form surfaces is a challenging one, even in the case of designing a single surface. Here we present a method for the coupled design of two free-form reflective surfaces that will have a prescribed distortion. On one hand, the method can be described using traditional vectors and matrices, which we do, but it is motivated by viewing the problem in the language of distributions from differential geometry and makes use of the exterior differential systems, which we relegate to an appendix. Example applications are given to the design of a mirror pair that increases the field of view of an observer, a similar mirror pair that also rotates the observer's view, and a pair of mirrors that give the observer a traditional panoramic strip view of the scene.

  2. Design and development of Propulsion System for Antitank Guided Missile

    Directory of Open Access Journals (Sweden)

    T. Mohan Reddy

    1995-07-01

    Full Text Available A Propulsion system is designed and developed for the third generation antitank guided missile (ATGM. It consists of a separate booster and sustainer. Booster is ahead of sustainer, having four nozzles canted to the missile axis. Sustainer discharges through a supersonic blast tube. Low smoke, high energy nitramine propellant for this propulsion system developed by the High Energy Materials Research Laboratory (HEMRL, Pune, has been successfully flight-tested. The booster grain is tube-in-tube configuration with end inhibition and the sustainer grain is of end burning configuration. High strength aluminium alloy, HE-15, is used for rocket motor components. Glass-phenolic composite ablative material is used for thermal protection of motors and high density graphite is used for nozzle throats. The design considerations and approach, including grain configuration, nozzle, and ignitersare briefly discussed. The propulsion system has been extensively tested in static tests and in flights, establishing the satisfactory performance of the system.

  3. Guiding, bending, and splitting of coupled defect surface modes in a surface-wave photonic crystal

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Zhen; Gao, Fei [Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore 637371 (Singapore); Zhang, Baile, E-mail: blzhang@ntu.edu.sg [Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore 637371 (Singapore); Centre for Disruptive Photonic Technologies, Nanyang Technological University, Singapore, Singapore 637371 (Singapore)

    2016-01-25

    We experimentally demonstrate a type of waveguiding mechanism for coupled surface-wave defect modes in a surface-wave photonic crystal. Unlike conventional spoof surface plasmon waveguides, waveguiding of coupled surface-wave defect modes is achieved through weak coupling between tightly localized defect cavities in an otherwise gapped surface-wave photonic crystal, as a classical wave analogue of tight-binding electronic wavefunctions in solid state lattices. Wave patterns associated with the high transmission of coupled defect surface modes are directly mapped with a near-field microwave scanning probe for various structures including a straight waveguide, a sharp corner, and a T-shaped splitter. These results may find use in the design of integrated surface-wave devices with suppressed crosstalk.

  4. Des Guides Joanne au Guide Vert Michelin : points, lignes, surfaces

    Directory of Open Access Journals (Sweden)

    Marie-Vic Ozouf-Marignier

    2011-06-01

    Full Text Available Cet article étudie la perception de l’espace dans les guides touristiques de la fin du XIXe siècle à nos jours. Il compare trois collections de guides français : les Guides Joanne, les Guides Bleus Hachette et les Guides Verts Michelin. Nous avons identifié trois moments majeurs. Dans une première période, le voyage en chemin de fer détermine une représentation linéaire de l’espace agrémentée de quelques coups d’œil à l’intérieur du paysage à l’endroit des stations. Dans une seconde période, le déplacement en voiture permet à une appréhension régionale de se développer. L’école française de géographie influence alors l’écriture des introductions de guide. Les rédacteurs introduisent de plus en plus de cartes dans ces ouvrages. L’unité régionale devient sensible, notamment du point de vue naturaliste. Toutefois, la recherche des curiosités, musées églises, châteaux et ruines se maintient également. De nos jours, l’autoroute, le train à grande vitesse et l’industrie touristique ont changé les pratiques et représentations de l’espace. Les touristes semblent apprécier le fait de collectionner les sites de visite et de faire des circuits à thème.This article deals with tourist perception of the space from the end of the nineteenth century to our days. It compares three collections of French tourist guides: Guides Joanne, blue guides Hachette and Guides Verts Michelin. Three main periods can be distinguished. First, railway travel determines linear representation of the landscape, with a few glances on the countryside at the stations. In a second period, the car mobility makes possible a surrounding vision of regions. French school of geography influences the prefaces of the guides. Editors introduce more and more maps inside the guides. Regional cohesion becomes perceptible, especially from a naturalistic point of view. Interesting sights, museums, churches, castles and ruins remain

  5. Textile Design: A Suggested Program Guide. Fashion Industry Series No. 3.

    Science.gov (United States)

    Fashion Inst. of Tech., New York, NY.

    The textile design guide is the third of a series of five interrelated program resource guides encompassing the various dimensions of the fashion industry. The job-preparatory guide is conceived to provide youth and adults with intensive preparation for initial entry employment and also with career advancement opportunities within specific…

  6. Design of the Mechanical Parts for the Neutron Guide System at HANARO

    Science.gov (United States)

    Shin, J. W.; Cho, Y. G.; Cho, S. J.; Ryu, J. S.

    2008-03-01

    The research reactor HANARO (High-flux Advanced Neutron Application ReactOr) in Korea will be equipped with a neutron guide system, in order to transport cold neutrons from the neutron source to the neutron scattering instruments in the neutron guide hall near the reactor building. The neutron guide system of HANARO consists of the in-pile plug assembly with in-pile guides, the primary shutter with in-shutter guides, the neutron guides in the guide shielding room with dedicated secondary shutters, and the neutron guides connected to the instruments in the neutron guide hall. Functions of the in-pile plug assembly are to shield the reactor environment from nuclear radiation and to support the neutron guides and maintain them precisely oriented. The primary shutter is a mechanical structure to be installed just after the in-pile plug assembly, which stops neutron flux on demand. This paper describes the design of the in-pile assembly and the primary shutter for the neutron guide system at HANARO. The design of the guide shielding assembly for the primary shutter and the neutron guides is also presented.

  7. Method of designing developable surface based on engineering requirement

    Institute of Scientific and Technical Information of China (English)

    YANG Ji-xin; LIU Zhe; LIU Jian

    2006-01-01

    The paper deals with the principle of envelope of a one-parameter plane family to design developable surfaces. Three methods of designing developable surfaces are presented. They are designing a developable surface based on one curve on it and its normal line, designing a developable surface based on two curves on it and designing a developable surface based on one curve and one surface. They meet the requirements of engineering fields.

  8. Guide on the use of low energy electron beams for microbiological decontamination of surfaces

    DEFF Research Database (Denmark)

    Miller, Arne; Helt-Hansen, Jakob; Gondim, Ondina

    This Guide describes the validation and routine monitoring of microbiological decontamination of surfaces by low energy electron beams (100-200 keV). The Guide is mainly based on experience gained in connection with installation of electron beam systems for surface decontamination of pre-steriliz......This Guide describes the validation and routine monitoring of microbiological decontamination of surfaces by low energy electron beams (100-200 keV). The Guide is mainly based on experience gained in connection with installation of electron beam systems for surface decontamination of pre......-sterilized containers at several aseptic filling lines at pharmaceutical manufacturers. Its main emphasis is on the dosimetric measurements that should be carried out for the validation of the decontamination process and on establishing the appropriate effective dose. Other aspects such as use of measurement...... uncertainties and formation of radiation induced by-products are also addressed....

  9. Surface design methodology - challenge the steel

    Science.gov (United States)

    Bergman, M.; Rosen, B.-G.; Eriksson, L.; Anderberg, C.

    2014-03-01

    The way a product or material is experienced by its user could be different depending on the scenario. It is also well known that different materials and surfaces are used for different purposes. When optimizing materials and surface roughness for a certain something with the intention to improve a product, it is important to obtain not only the physical requirements, but also the user experience and expectations. Laws and requirements of the materials and the surface function, but also the conservative way of thinking about materials and colours characterize the design of medical equipment. The purpose of this paper is to link the technical- and customer requirements of current materials and surface textures in medical environments. By focusing on parts of the theory of Kansei Engineering, improvements of the companys' products are possible. The idea is to find correlations between desired experience or "feeling" for a product, -customer requirements, functional requirements, and product geometrical properties -design parameters, to be implemented on new improved products. To be able to find new materials with the same (or better) technical requirements but a higher level of user stimulation, the current material (stainless steel) and its surface (brushed textures) was used as a reference. The usage of focus groups of experts at the manufacturer lead to a selection of twelve possible new materials for investigation in the project. In collaboration with the topical company for this project, three new materials that fulfil the requirements -easy to clean and anti-bacterial came to be in focus for further investigation in regard to a new design of a washer-disinfector for medical equipment using the Kansei based Clean ability approach CAA.

  10. Regulatory compliance guide for DOT-7A type A packaging design

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, D.L.

    1996-06-04

    The purpose of this guide is to provide instruction for assuring that the regulatory design requirements for a DOT-7A Type A packaging are met. This guide also supports the testing and evaluation activities that are performed on new packaging designs by a DOE-approved test facility through the DOE`s DOT-7A Test Program. This Guide was updated to incorporate regulatory changes implemented by HM-169A (49 CFR, `Transportation`).

  11. Apparel Design and Production: A Suggested Program Guide. Fashion Industry Series No. 2.

    Science.gov (United States)

    Fashion Inst. of Tech., New York, NY.

    The apparel design and production guide is the second of a series of five interrelated program resource guides encompassing the various dimensions of the fashion industry. Designed to provide youths and adults with intensive preparation for initial entry employment and also with career advancement opportunities within specific categories of jobs,…

  12. An analytical filter design method for guided wave phased arrays

    Science.gov (United States)

    Kwon, Hyu-Sang; Kim, Jin-Yeon

    2016-12-01

    This paper presents an analytical method for designing a spatial filter that processes the data from an array of two-dimensional guided wave transducers. An inverse problem is defined where the spatial filter coefficients are determined in such a way that a prescribed beam shape, i.e., a desired array output is best approximated in the least-squares sense. Taking advantage of the 2π-periodicity of the generated wave field, Fourier-series representation is used to derive closed-form expressions for the constituting matrix elements. Special cases in which the desired array output is an ideal delta function and a gate function are considered in a more explicit way. Numerical simulations are performed to examine the performance of the filters designed by the proposed method. It is shown that the proposed filters can significantly improve the beam quality in general. Most notable is that the proposed method does not compromise between the main lobe width and the sidelobe levels; i.e. a narrow main lobe and low sidelobes are simultaneously achieved. It is also shown that the proposed filter can compensate the effects of nonuniform directivity and sensitivity of array elements by explicitly taking these into account in the formulation. From an example of detecting two separate targets, how much the angular resolution can be improved as compared to the conventional delay-and-sum filter is quantitatively illustrated. Lamb wave based imaging of localized defects in an elastic plate using a circular array is also presented as an example of practical applications.

  13. Designing new guides and instruments using McStas

    DEFF Research Database (Denmark)

    Farhi, E.; Hansen, T.; Wildes, A.

    2002-01-01

    of guides, neutron optics and instruments [1]. To date, the McStas package has been extensively used at the Institut Laue-Langevin, Grenoble, France, for various studies including cold and thermal guides with ballistic geometry, diffractometers, triple-axis, backscattering and time-of-flight spectrometers...

  14. Designing polymer surfaces via vapor deposition

    Directory of Open Access Journals (Sweden)

    Ayse Asatekin

    2010-05-01

    Full Text Available Chemical Vapor Deposition (CVD methods significantly augment the capabilities of traditional surface modification techniques for designing polymeric surfaces. In CVD polymerization, the monomer(s are delivered to the surface through the vapor phase and then undergo simultaneous polymerization and thin film formation. By eliminating the need to dissolve macromolecules, CVD enables insoluble polymers to be coated and prevents solvent damage to the substrate. Since de-wetting and surface tension effects are absent, CVD coatings conform to the geometry of the underlying substrate. Hence, CVD polymers can be readily applied to virtually any substrate: organic, inorganic, rigid, flexible, planar, three-dimensional, dense, or porous. CVD methods integrate readily with other vacuum processes used to fabricate patterned surfaces and devices. CVD film growth proceeds from the substrate up, allowing for interfacial engineering, real-time monitoring, thickness control, and the synthesis of films with graded composition. This article focuses on two CVD polymerization methods that closely translate solution chemistry to vapor deposition; initiated CVD and oxidative CVD. The basic concepts underlying these methods and the resultant advantages over other thin film coating techniques are described, along with selected applications where CVD polymers are an enabling technology.

  15. Repository surface design site layout analysis

    Energy Technology Data Exchange (ETDEWEB)

    Montalvo, H.R.

    1998-02-27

    The purpose of this analysis is to establish the arrangement of the Yucca Mountain Repository surface facilities and features near the North Portal. The analysis updates and expands the North Portal area site layout concept presented in the ACD, including changes to reflect the resizing of the Waste Handling Building (WHB), Waste Treatment Building (WTB), Carrier Preparation Building (CPB), and site parking areas; the addition of the Carrier Washdown Buildings (CWBs); the elimination of the Cask Maintenance Facility (CMF); and the development of a concept for site grading and flood control. The analysis also establishes the layout of the surface features (e.g., roads and utilities) that connect all the repository surface areas (North Portal Operations Area, South Portal Development Operations Area, Emplacement Shaft Surface Operations Area, and Development Shaft Surface Operations Area) and locates an area for a potential lag storage facility. Details of South Portal and shaft layouts will be covered in separate design analyses. The objective of this analysis is to provide a suitable level of design for the Viability Assessment (VA). The analysis was revised to incorporate additional material developed since the issuance of Revision 01. This material includes safeguards and security input, utility system input (size and location of fire water tanks and pump houses, potable water and sanitary sewage rates, size of wastewater evaporation pond, size and location of the utility building, size of the bulk fuel storage tank, and size and location of other exterior process equipment), main electrical substation information, redundancy of water supply and storage for the fire support system, and additional information on the storm water retention pond.

  16. Design of Surface Micromachined Compliant MEMS

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, Joe Anthony [Iowa State Univ., Ames, IA (United States)

    2002-12-31

    The consideration of compliant mechanisms as Microelectromechanical Systems (MEMS) is the focus of this research endeavor. MEMS are micron to millimeter devices that combine electrical, mechanical, and information processing capabilities on the same device. These MEMS need some mechanical motion or parts that move relative to each other. This relative motion, using multiple parts, is not desired because of the assembly requirement and the friction introduced. Compliant devices limits or eliminates friction and the need for multi-component assembly. Compliant devices improve designs by creating single piece mechanisms. The purpose of this research is to validate surface micromachining as a viable fabrication process for compliant MEMS designs. Specifically, this research has sought to fabricate a micro-compliant gripper and a micro-compliant clamp to illustrate the process. While other researchers have created compliant MEMs, most have used comb-drive actuation methods and bulk micromachining processes. This research focused on fully-compliant devices that use device flexibility for motion and actuation. Validation of these compliant MEMS is achieved by structural optimization of device design and functional performance testing. This research contributes to the ongoing research in MEMS by evaluating the potential of using surface micromachining as a process for fabricating compliant micro-mechanisms.

  17. Design of Surface micromachined Compliant MEMS

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, Joe Anthony [Iowa State Univ., Ames, IA (United States)

    2001-01-01

    The consideration of compliant mechanisms as Microelectromechanical Systems (MEMS) is the focus of this research endeavor. MEMS are micron to millimeter devices that combine electrical, mechanical, and information processing capabilities on the same device. These MEMS need some mechanical motion or parts that move relative to each other. This relative motion, using multiple parts, is not desired because of the assembly requirement and the friction introduced. Compliant devices limits or eliminates friction and the need for multi-component assembly. Compliant devices improve designs by creating single piece mechanisms. The purpose of this research is to validate surface micromachining as a viable fabrication process for compliant MEMS designs. Specifically, this research has sought to fabricate a micro-compliant gripper and a micro-compliant clamp to illustrate the process. While other researchers have created compliant MEMS, most have used comb-drive actuation methods and bulk micromachining processes. This research focuses on fully-compliant devices that use device flexibility for motion and actuation. Validation of these compliant MEMS is achieved by structural optimization of device design and functional performance testing. This research contributes to the ongoing research in MEMS by evaluating the potential of using surface micromachining as a process for fabricating compliant micro-mechanisms.

  18. Design of Surface micromachined Compliant MEMS

    Energy Technology Data Exchange (ETDEWEB)

    Joe Anthony Bradley

    2002-08-01

    The consideration of compliant mechanisms as Microelectromechanical Systems (MEMS) is the focus of this research endeavor. MEMS are micron to millimeter devices that combine electrical, mechanical, and information processing capabilities on the same device. These MEMS need some mechanical motion or parts that move relative to each other. This relative motion, using multiple parts, is not desired because of the assembly requirement and the friction introduced. Compliant devices limits or eliminates friction and the need for multi-component assembly. Compliant devices improve designs by creating single piece mechanisms. The purpose of this research is to validate surface micromachining as a viable fabrication process for compliant MEMS designs. Specifically, this research has sought to fabricate a micro-compliant gripper and a micro-compliant clamp to illustrate the process. While other researchers have created compliant MEMS, most have used comb-drive actuation methods and bulk micromachining processes. This research focuses on fully-compliant devices that use device flexibility for motion and actuation. Validation of these compliant MEMS is achieved by structural optimization of device design and functional performance testing. This research contributes to the ongoing research in MEMS by evaluating the potential of using surface micromachining as a process for fabricating compliant micro-mechanisms.

  19. Photonic surfaces for designable nonlinear power shaping

    Energy Technology Data Exchange (ETDEWEB)

    Biswas, Roshni, E-mail: rbiswas@usc.edu; Povinelli, Michelle L. [Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, California 90089 (United States)

    2015-02-09

    We propose a method for designing nonlinear input-output power response based on absorptive resonances of nanostructured surfaces. We show that various power transmission trends can be obtained by placing a photonic resonance mode at the appropriate detuning from the laser wavelength. We demonstrate our results in a silicon photonic crystal slab at a laser wavelength of 808 nm. We quantify the overall spectral red shift as a function of laser power. The shift results from absorptive heating and the thermo-optic effect. We then demonstrate devices with increasing, decreasing, and non-monotonic transmission as a function of laser power. The transmission changes are up to 7.5 times larger than in unpatterned silicon. The strong nonlinear transmission is due to a combination of resonantly enhanced absorption, reduced thermal conductivity, and the resonant transmission lineshape. Our results illustrate the possibility of designing different nonlinear power trends within a single materials platform at a given wavelength of interest.

  20. A reference guide to microbial cell surface hydrophobicity based on contact angles

    NARCIS (Netherlands)

    van der Mei, HC; Busscher, HJ; Bos, R.R.M.

    1998-01-01

    Acid-base interactions form the origin of the hydrophobicity of microbial cell-surfaces and can be quantitated from contact angle measurements on microbial lawns with water, formamide, methyleneiodide and/or alpha-bromonaphthalene. This review provides a reference guide to microbial cell surface hyd

  1. Structural Integrity Evaluation of Cold Neutron Laboratory Building by Design Change of Guide Shielding Room

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Sangik; Kim, Youngki; Kim, Harkrho

    2007-06-15

    This report summarizes the results of the structural integrity evaluation for the cold neutron laboratory building by design change of guide shielding room. The design of the guide shielding room was changed by making its structure members in normal concrete (2.3 g/cc) instead of heavy concrete (3.5 g/cc) because the heavy concrete could be not supplied to meet its design specification. Therefore, it was decided that the guide shielding room is made of the normal concrete. And, the shielding performance of the normal concrete was recalculated to confirm satisfying its design specification, which is of a 9000 zone according to HANARO radiation region classification. The change makes the shielding wall thicker than existing design, and then it is caused to qualify the structural integrity evaluation of the CNLB. Finally, the structural integrity of the CNLB was re-evaluated by considering the design change of the guide shielding room.

  2. Low-cost Design and Manufacturing of Surgical Guides for Mandibular Reconstruction Using a Fibula

    OpenAIRE

    2016-01-01

    Background: Surgical cutting guides are used in mandibular reconstruction involving osteotomy of the mandible and fibula. Cutting guides produced using computer-aided design (CAD) and computer-aided manufacturing (CAM) technologies have been reported recently. These guides aim to increase the benefits to patients by improving the accuracy, shortening the operating time, and correcting occlusion. However, the availability of these advanced technologies is limited in some regions of the world. ...

  3. Designing new guides and instruments using McStas

    CERN Document Server

    Farhi, E; Wildes, A R; Ghosh, R; Lefmann, K

    2002-01-01

    With the increasing complexity of modern neutron-scattering instruments, the need for powerful tools to optimize their geometry and physical performances (flux, resolution, divergence, etc.) has become essential. As the usual analytical methods reach their limit of validity in the description of fine effects, the use of Monte Carlo simulations, which can handle these latter, has become widespread. The McStas program was developed at Riso National Laboratory in order to provide neutron scattering instrument scientists with an efficient and flexible tool for building Monte Carlo simulations of guides, neutron optics and instruments. To date, the McStas package has been extensively used at the Institut Laue-Langevin, Grenoble, France, for various studies including cold and thermal guides with ballistic geometry, diffractometers, triple-axis, backscattering and time-of-flight spectrometers. In this paper, we present some simulation results concerning different guide geometries that may be used in the future at th...

  4. Curves and surfaces for CAGD a practical guide

    CERN Document Server

    Farin, Gerald

    2002-01-01

    This fifth edition has been fully updated to cover the many advances made in CAGD and curve and surface theory since 1997, when the fourth edition appeared. Material has been restructured into theory and applications chapters. The theory material has been streamlined using the blossoming approach; the applications material includes least squares techniques in addition to the traditional interpolation methods. In all other respects, it is, thankfully, the same. This means you get the informal, friendly style and unique approach that has made Curves and Surfaces for CAGD: A Practical Gui

  5. Laser beam riding guided system principle and design research

    Science.gov (United States)

    Qu, Zhou; Jin, Yi; Xu, Zhou; Xing, Hao

    2016-01-01

    With the development of science and technology, precision-strike weapons has been considered to be important for winning victory in military field. Laser guidance is a major method to execute precision-strike in modern warfare. At present, the problems of primary stage of Laser guidance has been solved with endeavors of countries. Several technical aspects of laser-beam riding guided system have been mature, such as atmosphere penetration of laser beam, clutter inhibition on ground, laser irradiator, encoding and decoding of laser beam. Further, laser beam quality, equal output power and atmospheric transmission properties are qualified for warfare situation. Riding guidance instrument is a crucial element of Laser-beam riding guided system, and is also a vital element of airborne, vehicle-mounted and individual weapon. The optical system mainly consist of sighting module and laser-beam guided module. Photoelectric detector is the most important sensing device of seeker, and also the key to acquire the coordinate information of target space. Currently, in consideration of the 1.06 u m of wavelength applied in all the semi-active laser guided weapons systems, lithium drifting silicon photodiode which is sensitive to 1.06 u m of wavelength is used in photoelectric detector. Compared to Solid and gas laser, diode laser has many merits such as small volume, simple construction, light weight, long life, low lost and easy modulation. This article introduced the composition and operating principle of Laser-beam riding guided system based on 980 nm diode laser, and made a analysis of key technology; for instance, laser irradiator, modulating disk of component, laser zooming system. Through the use of laser diode, Laser-beam riding guided system is likely to have smaller shape and very light.

  6. Hydraulic design and pre-whirl regulation law of inlet guide vane for centrifugal pump

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A new hydraulic design method of three-dimensional guide vane for centrifugal pump is proposed on the assumption that the fluid at the outlet of guide vane satisfies the uniform velocity moment condition.The geometry of blade is controlled by the distributed rule of blade angles along the meridional streamline which is described by a fourth-order polynomial.Experiment results demonstrate that the designed guide vane can overcome the drawback of two-dimensional guide vane,enlarge the high efficiency scope and improve the hydraulic performance of centrifugal pump on the off-design operation conditions.In comparison with the performance of the centrifugal pump without inlet guide vane,the peak value of efficiency can be enhanced by 2.13% after the three-dimensional guide vane was being installed.The three-dimensional entire flow field of the centrifugal pump with inlet guide vane is simulated,and the basic principle and mechanism of inlet guide vane pre-whirl regulation are analyzed.The validity of design method has been proved.

  7. INSEAN REPORT DESCRIBING THE DESIGN OF THE CRANE AND THE CATAPULT SYSTEM FOR GUIDED DITCHING TESTS

    OpenAIRE

    Iafrati, Alessandro

    2012-01-01

    The present report describes the key points of the design of the facility to be used for the guided ditching test in T4.1. The system is made by three main components: guide, trolley, acceleration and release system (catapult). Each component is illustrated separately in the following.

  8. Venus Surface Power and Cooling System Design

    Science.gov (United States)

    Landis, Geoffrey A.; Mellott, Kenneth D.

    2004-01-01

    A radioisotope power and cooling system is designed to provide electrical power for the a probe operating on the surface of Venus. Most foreseeable electronics devices and sensors simply cannot operate at the 450 C ambient surface temperature of Venus. Because the mission duration is substantially long and the use of thermal mass to maintain an operable temperature range is likely impractical, some type of active refrigeration may be required to keep certain components at a temperature below ambient. The fundamental cooling requirements are comprised of the cold sink temperature, the hot sink temperature, and the amount of heat to be removed. In this instance, it is anticipated that electronics would have a nominal operating temperature of 300 C. Due to the highly thermal convective nature of the high-density atmosphere, the hot sink temperature was assumed to be 50 C, which provided a 500 C temperature of the cooler's heat rejecter to the ambient atmosphere. The majority of the heat load on the cooler is from the high temperature ambient surface environment on Venus. Assuming 5 cm radial thickness of ceramic blanket insulation, the ambient heat load was estimated at approximately 77 watts. With an estimated quantity of 10 watts of heat generation from electronics and sensors, and to accommodate some level of uncertainty, the total heat load requirement was rounded up to an even 100 watts. For the radioisotope Stirling power converter configuration designed, the Sage model predicts a thermodynamic power output capacity of 478.1 watts, which slightly exceeds the required 469.1 watts. The hot sink temperature is 1200 C, and the cold sink temperature is 500 C. The required heat input is 1740 watts. This gives a thermodynamic efficiency of 27.48 %. The maximum theoretically obtainable efficiency is 47.52 %. It is estimated that the mechanical efficiency of the power converter design is on the order of 85 %, based on experimental measurements taken from 500 watt power

  9. Interaction of impeller and guide vane in a series-designed axial-flow pump

    Science.gov (United States)

    Kim, S.; Choi, Y. S.; Lee, K. Y.; Kim, J. H.

    2012-11-01

    In this paper, the interaction of the impeller and guide vane in a series-designed axial-flow pump was examined through the implementation of a commercial CFD code. The impeller series design refers to the general design procedure of the base impeller shape which must satisfy the various flow rate and head requirements by changing the impeller setting angle and number of blades of the base impeller. An arc type meridional shape was used to keep the meridional shape of the hub and shroud with various impeller setting angles. The blade angle and the thickness distribution of the impeller were designed as an NACA airfoil type. In the design of the guide vane, it was necessary to consider the outlet flow condition of the impeller with the given setting angle. The meridional shape of the guide vane were designed taking into consideration the setting angle of the impeller, and the blade angle distribution of the guide vane was determined with a traditional design method using vane plane development. In order to achieve the optimum impeller design and guide vane, three-dimensional computational fluid dynamics and the DOE method were applied. The interaction between the impeller and guide vane with different combination set of impeller setting angles and number of impeller blades was addressed by analyzing the flow field of the computational results.

  10. 3D surface topology guides stem cell adhesion and differentiation.

    Science.gov (United States)

    Viswanathan, Priyalakshmi; Ondeck, Matthew G; Chirasatitsin, Somyot; Ngamkham, Kamolchanok; Reilly, Gwendolen C; Engler, Adam J; Battaglia, Giuseppe

    2015-06-01

    Polymerized high internal phase emulsion (polyHIPE) foams are extremely versatile materials for investigating cell-substrate interactions in vitro. Foam morphologies can be controlled by polymerization conditions to result in either open or closed pore structures with different levels of connectivity, consequently enabling the comparison between 2D and 3D matrices using the same substrate with identical surface chemistry conditions. Additionally, here we achieve the control of pore surface topology (i.e. how different ligands are clustered together) using amphiphilic block copolymers as emulsion stabilizers. We demonstrate that adhesion of human mesenchymal progenitor (hES-MP) cells cultured on polyHIPE foams is dependent on foam surface topology and chemistry but is independent of porosity and interconnectivity. We also demonstrate that the interconnectivity, architecture and surface topology of the foams has an effect on the osteogenic differentiation potential of hES-MP cells. Together these data demonstrate that the adhesive heterogeneity of a 3D scaffold could regulate not only mesenchymal stem cell attachment but also cell behavior in the absence of soluble growth factors.

  11. Through the Past Decade: How Advanced Energy Design Guides have influenced the Design Industry

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Bing; Athalye, Rahul A.

    2015-07-31

    Advanced Energy Design Guides (AEDGs) were originally developed intended to provide a simple approach to building professionals seeking energy efficient building designs better than ASHRAE Standard 90.1. Since its first book was released in 2004, the AEDG series provided inspiration for the design industry and were seen by designers as a starting point for buildings that wished to go beyond minimum codes and standards. In addition, U.S. Department of Energy’s successful Commercial Building Partnerships (CBP) program leveraged many of the recommendations from the AEDGs to achieve 50% energy savings over ASHRAE Standard 90.1-2004 for prototypical designs of large commercial entities in the retail, banking and lodging sectors. Low-energy technologies and strategies developed during the CBP process have been applied by commercial partners throughout their national portfolio of buildings. Later, the AEDGs served as the perfect platform for both Standard 90.1 and ASHRAE’s high performance buildings standard, Standard 189.1. What was high performance a few years ago, however, has become minimum code today. Indeed, most of the prescriptive envelope component requirements in ASHRAE Standard 90.1-2013 are values recommended in the 50% AEDGs several years ago. Similarly, AEDG strategies and recommendations have penetrated the lighting and HVAC sections of both Standard 189.1 and Standard 90.1. Finally, as we look to the future of codes and standards, the AEDGs are serving as a blueprint for how minimum code requirements could be expressed. By customizing codes to specific building types, design strategies tailored for individual buildings could be prescribed as minimum code, just like in the AEDGs. This paper describes the impact that AEDGs have had over the last decade on the design industry and how they continue to influence the future of codes and Standards. From design professionals to code officials, everyone in the building industry has been affected by the AEDGs.

  12. Service design based on ITIL V3 a management guide

    CERN Document Server

    Bon, Jan van; Kolthof, Axel

    2010-01-01

    This Management Guide is a concise summary of the IT Service Management ? An Introduction. A quick, portable reference tool to the standards used within the Service Management community.What are the key service management processes? What is the ?lifecycle? approach?What are the elements of ISO20000? All this and descriptions of other popular frameworks are covered.

  13. Designing Aquatic Exercise Programs--Three Guiding Principles.

    Science.gov (United States)

    White, Sue W.; Landis, Larry M.

    1989-01-01

    Three guiding principles provide the planner of aquatic exercise programs with a model that helps to ensure an effective program: principles of resource availability and allocation; the principle of fit, which involves matching instructor leadership style with program objectives; and the principle of attitude and perception modification. (IAH)

  14. Designing new guides and instruments using McStas

    Energy Technology Data Exchange (ETDEWEB)

    Farhi, E.; Hansen, T.; Wildes, A.; Ghosh, R. [Institut Laue-Langevin, BP 156, 38042 Grenoble Cedex 9 (France); Lefmann, K. [Riso National Laboratory, Fredericksborgveg 399, 4000 Roskilde (Denmark)

    2002-07-01

    With the increasing complexity of modern neutron-scattering instruments, the need for powerful tools to optimize their geometry and physical performances (flux, resolution, divergence, etc.) has become essential. As the usual analytical methods reach their limit of validity in the description of fine effects, the use of Monte Carlo simulations, which can handle these latter, has become widespread. The McStas program was developed at Riso National Laboratory in order to provide neutron scattering instrument scientists with an efficient and flexible tool for building Monte Carlo simulations of guides, neutron optics and instruments. To date, the McStas package has been extensively used at the Institut Laue-Langevin, Grenoble, France, for various studies including cold and thermal guides with ballistic geometry, diffractometers, triple-axis, backscattering and time-of-flight spectrometers. In this paper, we present some simulation results concerning different guide geometries that may be used in the future at the Institut Laue-Langevin. Gain factors ranging from two to five may be obtained for the integrated intensities, depending on the exact geometry, the guide coatings and the source. (orig.)

  15. Designing new guides and instruments using McStas

    Science.gov (United States)

    Farhi, E.; Hansen, T.; Wildes, A.; Ghosh, R.; Lefmann, K.

    With the increasing complexity of modern neutron-scattering instruments, the need for powerful tools to optimize their geometry and physical performances (flux, resolution, divergence, etc.) has become essential. As the usual analytical methods reach their limit of validity in the description of fine effects, the use of Monte Carlo simulations, which can handle these latter, has become widespread. The McStas program was developed at Riso National Laboratory in order to provide neutron scattering instrument scientists with an efficient and flexible tool for building Monte Carlo simulations of guides, neutron optics and instruments [1]. To date, the McStas package has been extensively used at the Institut Laue-Langevin, Grenoble, France, for various studies including cold and thermal guides with ballistic geometry, diffractometers, triple-axis, backscattering and time-of-flight spectrometers [2]. In this paper, we present some simulation results concerning different guide geometries that may be used in the future at the Institut Laue-Langevin. Gain factors ranging from two to five may be obtained for the integrated intensities, depending on the exact geometry, the guide coatings and the source.

  16. Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review.

    Directory of Open Access Journals (Sweden)

    Miranta Antoniou

    Full Text Available Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utilizing a patient's biomarker information in clinical practice, robust testing in terms of analytical validity, clinical validity and clinical utility is necessary. A number of clinical trial designs have been proposed for testing a biomarker's clinical utility, including Phase II and Phase III clinical trials which aim to test the effectiveness of a biomarker-guided approach to treatment; these designs can be broadly classified into adaptive and non-adaptive. While adaptive designs allow planned modifications based on accumulating information during a trial, non-adaptive designs are typically simpler but less flexible.We have undertaken a comprehensive review of biomarker-guided adaptive trial designs proposed in the past decade. We have identified eight distinct biomarker-guided adaptive designs and nine variations from 107 studies. Substantial variability has been observed in terms of how trial designs are described and particularly in the terminology used by different authors. We have graphically displayed the current biomarker-guided adaptive trial designs and summarised the characteristics of each design.Our in-depth overview provides future researchers with clarity in definition, methodology and terminology for biomarker-guided adaptive trial designs.

  17. Book Review--Humanitarian Intelligence: A Practitioner’s Guide to Crisis Analysis and Design

    Directory of Open Access Journals (Sweden)

    Henry Prunckun

    2017-05-01

    Full Text Available Book Review of: "Humanitarian Intelligence: A Practitioner’s Guide to Crisis Analysis and Design" by Andrej Zwitter, Rowman & Littlefield, Lanham, Maryland, 2016, hardcover, 232 pages, ISBN–9781442249486 Reviewed by Henry Prunckun

  18. Optimal Design of Surface Structure of a Magnetic Head

    Institute of Scientific and Technical Information of China (English)

    WANG Yazhen; NIU Rongjun; HUANG Ping

    2009-01-01

    Currently, the surface structure of a magnetic head has been transferred from a positive to a negative model. In order to increase magnetic storage density and to decrease the flight height, the surface structure of a head needs to be optimized continually. In the present paper, the influence of surface structure of a negative magnetic head on its flight attitude is analyzed in brief by both theoretical analysis and numerical simulation. Firstly, based on theoretical analysis, one-dimensional model of optimal design is built whose results play an important role in guiding for the two-dimensional model. Secondly, to analyze the impacts of different structures of negative pressure heads, the original head structure is divided into five zones;the impacts of different zones on both pressure distribution and load carrying capacity were detailed analyzed by numerical analysis. Thirdly, remain the leading-head structure of the negative head, and optimized tail-end structure can be gained by the regional planning strategy to control the gas film pressure distribution. With layout strategy, three kinds of structures of the head were designed. The results show that the tail-end structure impacts on the flight performances significantly and the middle boss plays a major role on positive pressure, while the bilateral bosses lying in either side play assistant regulating role. The structures of bilateral bosses have slightly impact on pressure distribution. The results also show that an optimum tail structure can meet the needs of a lower flight height and a larger magnetic storage density.

  19. Visualization of Guided Wave Propagation with Laser Doppler Vibrometer Scanning on Curved Surfaces

    Science.gov (United States)

    Hayashi, T.; Kojika, Y.; Kataoka, K.; Takikawa, M.

    2008-02-01

    In guided wave inspection for pipes, defect characterization is performed by echoes from defects. However, since detected signals become very complex due to mode conversion and multiple reflections, wave mechanics in a pipe with defects are not well studied. In this study, therefore, visualization technique for guided waves in a pipe is developed. In order to visualize guided wave propagation in a pipe, we need to scan an ultrasonic probe and measure ultrasonic waves at many points on a surface of a pipe. Position and posture of a laser doppler vibrometer are controlled by a robot arm, and ultrasonic vibration is detected at arbitrary points from arbitrary laser beam direction. Using the laser scanning technique, reflected guided waves from a shallow round defect was observed in the visualization results. From the defect, reflected waves propagated spirally in the oblique direction. From the view point of guided wave, the spiral waves were very high order modes that have not been measured in guided wave inspection. This result shows that such high order guided wave modes should be useful for defect characterization as well as low order modes.

  20. Guide design study for the high-resolution backscattering spectrometer FIRES

    Energy Technology Data Exchange (ETDEWEB)

    Pelley, C; Kargl, F; Sakai, V Garcia; Telling, M T F; Fernandez-Alonso, F; Demmel, F, E-mail: franz.demmel@stfc.ac.uk

    2010-11-01

    Different options are considered to transport cold neutrons along 90 m for the proposed new spectrometer FIRES at the ISIS facility. Monte Carlo simulations using the McStas programme package are used to assess the performance of various guide designs from the biological shield to the sample position. By employing a curved geometry, to avoid the direct line of sight, a hybrid design which combines a curved ballistic guide and an elliptic focusing section appears to be the best solution.

  1. Design of a high efficiency relativistic backward wave oscillator with low guiding magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoze; Song, Wei; Tan, Weibing; Zhang, Ligang; Su, Jiancang; Zhu, Xiaoxin; Hu, Xianggang; Shen, Zhiyuan; Liang, Xu; Ning, Qi [Science and Technology on High Power Microwave Laboratory, Northwest Institute of Nuclear Technology, Xi' an 710024 (China)

    2016-07-15

    A high efficiency relativistic backward wave oscillator working at a low guiding magnetic field is designed and simulated. A trapezoidal resonant reflector is used to reduce the modulation field in the resonant reflector to avoid overmodulation of the electron beam which will lead to a large momentum spread and then low conversion efficiency. The envelope of the inner radius of the slow wave structure (SWS) increases stepwise to keep conformal to the trajectory of the electron beam which will alleviate the bombardment of the electron on the surface of the SWS. The length of period of the SWS is reduced gradually to make a better match between phase velocity and electron beam, which decelerates continually and improves the RF current distribution. Meanwhile the modulation field is reduced by the introduction of nonuniform SWS also. The particle in cell simulation results reveal that a microwave with a power of 1.8 GW and a frequency of 14.7 GHz is generated with an efficiency of 47% when the diode voltage is 620 kV, the beam current 6.1 kA, and the guiding magnetic field 0.95 T.

  2. Investigation of nanoparticle transformations to guide the design of greener products and processes

    Science.gov (United States)

    Hutchison, James

    2012-02-01

    Nanoscale particles and products containing nanoparticles hold promise as higher performance materials; however, there are concerns that the production and use of nanoparticles might negatively impact human health or the environment. Within the context of greener nanoscience we aim to maximize the benefits, while minimizing hazards, of nanoscale products. A significant gap in the knowledge needed to develop greener products and processes is our understanding of the formation and transformation of nanoparticles. Such studies of nanoparticle dynamics are technically challenging and few studies have been reported. In this presentation, I will describe convenient methods to monitor nanoparticle dynamics and show how knowledge of nanoparticle transformations can guide the design of greener products and processes. In one example, chemically-modified transmission electron microscopy (TEM) grids are used to directly visualize silver nanoparticle transformations on surfaces. By indexing the TEM grids, it was possible to examine the same nanoparticles repeatedly throughout exposure to different environments. These studies show that larger particles can act as a source of smaller nanoparticles and that much larger particles also produce nanoparticles. With this knowledge, an improved design of nanoparticle coatings for antimicrobial fabrics was developed. A second example involves the use of small angle x-ray scattering (SAXS) to monitor nanoparticle formation reactions in solution in real-time. A combination of beam-line and lab-scale SAXS measurements, combined with simultaneous optical studies, showed that particle growth and coalescence compete under typical synthesis conditions, leading to loss of structural definition of the product. This mechanistic insight, in turn, guided the design of efficient and greener syntheses of well-defined nanoparticles.

  3. Experimental Investigation on Design Enhancement of Axial Fan Using Fixed Guide Vane

    Science.gov (United States)

    Munisamy, K. M.; Govindasamy, R.; Thangaraju, S. K.

    2015-09-01

    Airflow passes through the rotating blade in an axial flow fan will experience a helical flow pattern. This swirling effect leads the system to experience swirl energy losses or pressure drop yet reducing the total efficiency of the fan system. A robust tool to encounter this air spin past the blade is by introducing guide vane to the system. Owing to its importance, a new approach in designing outlet guide vane design for a commercial usage 1250mm diameter axial fan with a 30° pitch angle impeller has been introduced in this paper. A single line metal of proper curvature guide vane design technique has been adopted for this study. By choosing fan total efficiency as a target variable to be improved, the total and static pressure on the design point were set to be constraints. Therefore, the guide vane design was done based on the improvement target on the static pressure in system. The research shows that, with the improvement in static pressure by 29.63% through guide vane installation, the total fan efficiency is increased by 5.12%, thus reduces the fan power by 5.32%. Good agreement were found, that when the fan total efficiency increases, the power consumption of the fan is reduced. Therefore, this new approach of guide vane design can be applied to improve axial fan performance.

  4. Hydro-economic modeling of conjunctive ground and surface water use to guide sustainable basin management

    Science.gov (United States)

    Taher Kahil, Mohamed; Ward, Frank A.; Albiac, Jose; Eggleston, Jack; Sanz, David

    2016-04-01

    Water demands for irrigation, urban and environmental uses in arid and semiarid regions continue to grow, while freshwater supplies from surface and groundwater resources are becoming scarce and are expected to decline with climate change. Policymakers in these regions face hard choices on water management and policies. Hydro-economic modeling is the state-of-the art tool that could be used to guide the design and implementation of sustainable water management policies in basins. The strength of hydro-economic modeling lies in its capacity to integrate key biophysical and socio-economic components within a unified framework. A major gap in developments on hydro-economic modeling to date has been the weak integration of surface and groundwater flows, based on the theoretically correct Darcy equations used by the hydrogeological community. The modeling approach taken here is integrated, avoiding the single-tank aquifer assumption, avoiding simplified assumptions on aquifer-river linkages, and bypassing iterations among separate hydrological and economic models. The groundwater flow formulation used in this paper harnesses the standard finite difference expressions for groundwater flow and groundwater-surface water exchange developed in the USGS MODFLOW groundwater model. The methodological contribution to previous modeling efforts is the explicit specification of aquifer-river interactions, important when aquifer systems make a sizable contribution to basin resources. The modeling framework is solved completely, and information among the economic and hydrological components over all periods and locations are jointly and simultaneously determined. This novel framework is applied to the Jucar basin (Spain), which is a good experimental region for an integrated basin scale analysis. The framework is used for assessing the impacts of a range of climate change scenarios and policy choices, especially the hydrologic, land use, and economic outcomes. The modeling framework

  5. Design of a lunar surface structure

    Science.gov (United States)

    Mottaghi, Sohrob

    The next step for manned exploration and settlement is a return to the Moon. In such a return, the most challenging task is the construction of structures for habitation, considering the Moon's hostile environment. Therefore the question is: What is the best way to erect habitable structures on the lunar surface? Given the cost associated with bringing material to the Moon, In-Situ Resource Utilization (ISRU) is viewed by most as the basis for a successful manned exploration and settlement of the Solar system. Along these lines, we propose an advanced concept where the use of freeform fabrication technologies by autonomous mini-robots can form the basis for habitable lunar structures. Also, locally-available magnesium is proposed as the structural material. While it is one of the most pervasive metals in the regolith, magnesium has been only suggested only briefly as a viable option in the past. Therefore, a study has been conducted on magnesium and its alloys, taking into account the availability of the alloying elements on the Moon. An igloo-shaped magnesium structure, covered by sandbags of regolith shielding and supported on a sintered regolith foundation, is considered as a potential design of a lunar base, as well as the test bed for the proposed vision. Three studies are carried out: First a static analysis is conducted which proves the feasibility of the proposed material and method. Second, a thermal analysis is carried out to study the effect of the regolith shielding as well as the sensitivity of such designs to measurement uncertainties of regolith and sintered thermal properties. The lunar thermal environment is modeled for a potential site at 88º latitude in the lunar South Pole Region. Our analysis shows that the uncertainties are in an acceptable range where a three-meter thick shield is considered. Also, the required capacity of a thermal rejection system is estimated, choosing the thermal loads to be those of the Space Station modules. In the

  6. Guiding catalytically active particles with chemically patterned surfaces

    CERN Document Server

    Uspal, W E; Dietrich, S; Tasinkevych, M

    2016-01-01

    Catalytically active Janus particles suspended in solution create gradients in the chemical composition of the solution along their surfaces, as well as along any nearby container walls. The former leads to self-phoresis, while the latter gives rise to chemi-osmosis, providing an additional contribution to self-motility. Chemi-osmosis strongly depends on the molecular interactions between the diffusing chemical species and the wall. We show analytically, using an approximate "point-particle" approach, that by chemically patterning a planar substrate one can direct the motion of Janus particles: the induced chemi-osmotic flows can cause particles to either "dock" at the chemical step between the two materials, or to follow a chemical stripe. These theoretical predictions are confirmed by full numerical calculations. Generically, docking occurs for particles which tend to move away from their catalytic caps, while stripe-following occurs in the opposite case. Our analysis reveals the physical mechanisms governi...

  7. A Guide to Microsoft Active Directory (AD) Design

    Energy Technology Data Exchange (ETDEWEB)

    Dias, J

    2002-04-29

    The goal of this paper is to facilitate the design process for those DOE sites that are currently engaged in designing their Active Directory (AD) network. It is a roadmap to enable analysis of the complicated design tradeoffs associated with Active Directory Design. By providing discussion of Active Directory design elements which are permanent and costly to change once deployed, the hope is to minimize the risks of sponsoring failed designs, or joining existing infrastructures not suitable to programmatic needs. Specifically, most Active Directory structures will fall under one of three common designs: Single Domain, Single Forest with Multiple Domains, or Multiple Forests. Each has benefits and concerns, depending on programmatic and organizational structures. The comparison of these three approaches will facilitate almost any Active Directory design effort. Finally, this paper describes some best practices to consider when designing Active Directory based on three years of research and experience.

  8. Surface water management: a user's guide to calculate a water balance using the CREAMS model

    Energy Technology Data Exchange (ETDEWEB)

    Lane, L.J.

    1984-11-01

    The hydrologic component of the CREAMS model is described and discussed in terms of calculating a surface water balance for shallow land burial systems used for waste disposal. Parameter estimates and estimation procedures are presented in detail in the form of a user's guide. Use of the model is illustrated with three examples based on analysis of data from Los Alamos, New Mexico and Rock Valley, Nevada. Use of the model in design of trench caps for shallow land burial systems is illustrated with the example applications at Los Alamos.

  9. Guiding catalytically active particles with chemically patterned surfaces

    Science.gov (United States)

    Uspal, William; Popescu, Mihail; Dietrich, Siegfried; Tasinkevych, Mykola

    Catalytically active Janus particles in solution create gradients in the chemical composition of the solution along their surfaces, as well as along any nearby container walls. The former leads to self-phoresis, while the latter gives rise to chemi-osmosis, providing an additional contribution to self-motility. Chemi-osmosis strongly depends on the molecular interactions between the diffusing chemical species and the wall. We show analytically, using an approximate ``point-particle'' approach, that by chemically patterning a planar substrate (e.g., by adsorbing two different materials) one can direct the motion of Janus particles: the induced chemi-osmotic flows can cause particles to either ``dock'' at a chemical step between the two materials, or to follow a chemical stripe. These theoretical predictions are confirmed by full numerical calculations. Generically, docking occurs for particles which tend to move away from their catalytic caps, while stripe-following occurs in the opposite case. Our analysis reveals the physical mechanisms governing this behavior.

  10. Reliable design of electronic equipment an engineering guide

    CERN Document Server

    Natarajan, Dhanasekharan

    2014-01-01

    This book explains reliability techniques with examples from electronics design for the benefit of engineers. It presents the application of de-rating, FMEA, overstress analyses and reliability improvement tests for designing reliable electronic equipment. Adequate information is provided for designing computerized reliability database system to support the application of the techniques by designers. Pedantic terms and the associated mathematics of reliability engineering discipline are excluded for the benefit of comprehensiveness and practical applications. This book offers excellent support

  11. A Facilities Manager's Guide to Green Building Design.

    Science.gov (United States)

    Simpson, Walter

    2001-01-01

    Explains how the "green building" approach to educational facilities design creates healthy, naturally lit, attractive buildings with lower operating and life cycle costs. Tips on getting started on a green design and overcoming the barriers to the green design concept are discussed. (GR)

  12. Energy efficient building design. A transfer guide for local governments

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    The fundamental concepts of the building design process, energy codes and standards, and energy budgets are introduced. These tools were combined into Energy Design Guidelines and design contract requirements. The Guidelines were repackaged for a national audience and a videotape for selling the concept to government executives. An effort to test transfer of the Guidelines to outside agencies is described.

  13. Design guide for Category III reactors: pool type reactors. [US DOE

    Energy Technology Data Exchange (ETDEWEB)

    Brynda, W J; Lobner, P R; Powell, R W; Straker, E A

    1978-11-01

    The Department of Energy (DOE) in the ERDA Manual requires that all DOE-owned reactors be sited, designed, constructed, modified, operated, maintained, and decommissioned in a manner that gives adequate consideration to health and safety factors. Specific guidance pertinent to the safety of DOE-owned reactors is found in Chapter 0540 of the ERDA Manual. The purpose of this Design Guide is to provide additional guidance to aid the DOE facility contractor in meeting the requirement that the siting, design, construction, modification, operation, maintenance, and decommissioning of DOE-owned reactors be in accordance with generally uniform standards, guides, and codes which are comparable to those applied to similar reactors licensed by the Nuclear Regulatory Commission (NRC). This Design Guide deals principally with the design and functional requirement of Category III reactor structures, components, and systems.

  14. Design guide for category II reactors light and heavy water cooled reactors. [US DOE

    Energy Technology Data Exchange (ETDEWEB)

    Brynda, W J; Lobner, P R; Powell, R W; Straker, E A

    1978-05-01

    The Department of Energy (DOE), in the ERDA Manual, requires that all DOE-owned reactors be sited, designed, constructed, modified, operated, maintained, and decommissioned in a manner that gives adequate consideration to health and safety factors. Specific guidance pertinent to the safety of DOE-owned reactors is found in Chapter 0540 of the ERDA Manual. The purpose of this Design Guide is to provide additional guidance to aid the DOE facility contractor in meeting the requirement that the siting, design, construction, modification operation, maintainance, and decommissioning of DOW-owned reactors be in accordance with generally uniform standards, guide and codes which are comparable to those applied to similar reactors licensed by the Nuclear Regulatory Commission (NRC). This Design Guide deals principally with the design and functional requirements of Category II reactor structure, components, and systems.

  15. Vaadin 7 UI design by example beginner's guide

    CERN Document Server

    Duarte, Alejandro

    2013-01-01

    This book is a hands-on Beginner's Guide for developers who are new to Vaadin and/or Vaadin UI components. The book will teach readers through examples to use each of the exciting components to build and add various aspects of the user interface to their web apps.If you have experience with the Java language and want to create web applications that look good without having to deal with HTML, XML, and JavaScript, this book is for you. Basic Java programming skills are required, but no web development knowledge is needed at all.

  16. Algorithm Design and Test of the Solar Guide Telescope

    Institute of Scientific and Technical Information of China (English)

    Wei-Bin Wen; Sheng-Zhen Jin

    2004-01-01

    The Solar Guide Telescope (SGT), an important solar attitude sensor of the SST (Space Solar Telescope, a space solar observing instrument being developed in China), can accurately produce pointing error signals of the SST for attitude control at high speed. We analyze in detail the error algorithm of the heliocentric coordinates and the edge judging of solar images. The measuring accuracy of ±0.5arcsec of the SGT is verified by experiments on the tracking of the Sun and by testing a sun simulator. Some factors causing the pointing errors are examined.

  17. Swipe this! the guide to great touchscreen game design

    CERN Document Server

    Rogers, Scott

    2012-01-01

    Learn to design games for tablets from a renowned game designer! Eager to start designing games for tablets but not sure where to start? Look no further! Gaming guru Scott Rogers has his finger on the pulse of tablet game design and is willing to impart his wisdom and secrets for designing exciting and successful games. As the creator of such venerable games as God of War, the SpongeBob Squarepants series, and Pac-Man World, to name a few, Rogers writes from personal experience and in this unique book, he hands you the tools to create your own tablet games for the iPad, Android tablets, Ninten

  18. Designing an ultrafast laser virtual laboratory using MATLAB GUIDE

    Science.gov (United States)

    Cambronero-López, F.; Gómez-Varela, A. I.; Bao-Varela, C.

    2017-05-01

    In this work we present a virtual simulator developed using the MATLAB GUIDE environment based on the numerical resolution of the nonlinear Schrödinger equation (NLS) and using the split step method for the study of the spatial-temporal propagation of nonlinear ultrashort laser pulses. This allows us to study the spatial-temporal propagation of ultrafast pulses as well as the influence of high-order spectral phases such as group delay dispersion and third-order dispersion on pulse compression in time. The NLS can describe several nonlinear effects, in particular in this paper we consider the Kerr effect, cross-polarized wave generation and cubic-quintic propagation in order to highlight the potential of this equation combined with the GUIDE environment. Graphical user interfaces are commonly used in science and engineering teaching due to their educational value, and have proven to be an effective way to engage and motivate students. Specifically, the interactive graphical interfaces presented provide the visualization of some of the most important nonlinear optics phenomena and allows users to vary the values of the main parameters involved.

  19. Guiding, bending, and splitting of coupled defect surface modes in a surface-wave photonic crystal

    CERN Document Server

    Gao, Zhen; Zhang, Baile

    2016-01-01

    We experimentally demonstrate a type of waveguiding mechanism for coupled surface-wave defect modes in a surface-wave photonic crystal. Unlike conventional spoof surface plasmon waveguides, waveguiding of coupled surface-wave defect modes is achieved through weak coupling between tightly localized defect cavities in an otherwise gapped surface-wave photonic crystal, as a classical wave analogue of tight-binding electronic wavefunctions in solid state lattices.

  20. Surface-functionalized nanoparticles for biosensing and imaging-guided therapeutics.

    Science.gov (United States)

    Jiang, Shan; Win, Khin Yin; Liu, Shuhua; Teng, Choon Peng; Zheng, Yuangang; Han, Ming-Yong

    2013-04-21

    In this article, the very recent progress of various functional inorganic nanomaterials is reviewed including their unique properties, surface functionalization strategies, and applications in biosensing and imaging-guided therapeutics. The proper surface functionalization renders them with stability, biocompatibility and functionality in physiological environments, and further enables their targeted use in bioapplications after bioconjugation via selective and specific recognition. The surface-functionalized nanoprobes using the most actively studied nanoparticles (i.e., gold nanoparticles, quantum dots, upconversion nanoparticles, and magnetic nanoparticles) make them an excellent platform for a wide range of bioapplications. With more efforts in recent years, they have been widely developed as labeling probes to detect various biological species such as proteins, nucleic acids and ions, and extensively employed as imaging probes to guide therapeutics such as drug/gene delivery and photothermal/photodynamic therapy.

  1. Surface-functionalized nanoparticles for biosensing and imaging-guided therapeutics

    Science.gov (United States)

    Jiang, Shan; Win, Khin Yin; Liu, Shuhua; Teng, Choon Peng; Zheng, Yuangang; Han, Ming-Yong

    2013-03-01

    In this article, the very recent progress of various functional inorganic nanomaterials is reviewed including their unique properties, surface functionalization strategies, and applications in biosensing and imaging-guided therapeutics. The proper surface functionalization renders them with stability, biocompatibility and functionality in physiological environments, and further enables their targeted use in bioapplications after bioconjugation via selective and specific recognition. The surface-functionalized nanoprobes using the most actively studied nanoparticles (i.e., gold nanoparticles, quantum dots, upconversion nanoparticles, and magnetic nanoparticles) make them an excellent platform for a wide range of bioapplications. With more efforts in recent years, they have been widely developed as labeling probes to detect various biological species such as proteins, nucleic acids and ions, and extensively employed as imaging probes to guide therapeutics such as drug/gene delivery and photothermal/photodynamic therapy.

  2. Practical guide to saddle-point construction in lens design

    NARCIS (Netherlands)

    Bociort, F.; Van Turnhout, M.; Marinescu, O.

    2007-01-01

    Saddle-point construction (SPC) is a new method to insert lenses into an existing design. With SPC, by inserting and extracting lenses new system shapes can be obtained very rapidly, and we believe that, if added to the optical designer’s arsenal, this new tool can significantly increase design prod

  3. Smart heat guide: designing efficiently with ambient thermal energy

    NARCIS (Netherlands)

    Fremouw, M.

    2012-01-01

    This "designers' manual" is made during the TIDO-course AR0531 Smart & Bioclimatic Design. There are a few issues in our current energy use. We do not know how long the finite primary sources will last. The process of energy conversion makes very inefficient use of the primary energy sources. There

  4. Practical guide to saddle-point construction in lens design

    NARCIS (Netherlands)

    Bociort, F.; Van Turnhout, M.; Marinescu, O.

    2007-01-01

    Saddle-point construction (SPC) is a new method to insert lenses into an existing design. With SPC, by inserting and extracting lenses new system shapes can be obtained very rapidly, and we believe that, if added to the optical designer’s arsenal, this new tool can significantly increase design

  5. STORMWATER BEST MANAGEMENT PRACTICES DESIGN GUIDE VOLUME 2 - VEGETATIVE BIOFILTERS

    Science.gov (United States)

    This document is Volume 2 of a three volume document that provides guidance on the selection and design of stormwater management Best Management Practices (BMPs). This second volume provides specific design guidance for a group of onsite BMP control practices that are referred t...

  6. STORMWATER BEST MANAGEMENT PRACTICES DESIGN GUIDE VOLUME 2 - VEGETATIVE BIOFILTERS

    Science.gov (United States)

    This document is Volume 2 of a three volume document that provides guidance on the selection and design of stormwater management Best Management Practices (BMPs). This second volume provides specific design guidance for a group of onsite BMP control practices that are referred t...

  7. OPTIMAL KINEMATIC DESIGN OF A CAR AXLE GUIDING MECHANISM IN MBS SOFTWARE ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Cătălin ALEXANDRU

    2015-05-01

    Full Text Available This work deals with the optimal kinematic design of the guiding mechanism used for the rear axle of a motor vehicle. A guiding mechanism of type 2S1C (S - sphere, C - circle is taken into consideration, the optimization study being conducted by using the multi-body systems (MBS software environment ADAMS of MSC. The global cartesian coordinates of some design points (the locations of the joints between the guiding arms and car body are used as independent design variables for the optimization study. The main design objectives refer to the longitudinal displacement of the axle and its proper rotation (around the transversal axis, the kinematic optimization goal being to minimize these variations.

  8. Dramatic Enhancement of Genome Editing by CRISPR/Cas9 Through Improved Guide RNA Design

    OpenAIRE

    Farboud, B; Meyer,BJ

    2015-01-01

    © 2015 by the Genetics Society of America.Success with genome editing by the RNA-programmed nuclease Cas9 has been limited by the inability to predict effective guide RNAs and DNA target sites. Not all guide RNAs have been successful, and even those that were, varied widely in their efficacy. Here we describe and validate a strategy for Caenorhabditis elegans that reliably achieved a high frequency of genome editing for all targets tested in vivo. The key innovation was to design guide RNAs w...

  9. Dramatic Enhancement of Genome Editing by CRISPR/Cas9 Through Improved Guide RNA Design

    OpenAIRE

    Farboud, B; Meyer, BJ

    2015-01-01

    © 2015 by the Genetics Society of America. Success with genome editing by the RNA-programmed nuclease Cas9 has been limited by the inability to predict effective guide RNAs and DNA target sites. Not all guide RNAs have been successful, and even those that were, varied widely in their efficacy. Here we describe and validate a strategy for Caenorhabditis elegans that reliably achieved a high frequency of genome editing for all targets tested in vivo. The key innovation was to design guide RNAs ...

  10. Methodology of Computer-Aided Design of Variable Guide Vanes of Aircraft Engines

    Science.gov (United States)

    Falaleev, Sergei V.; Melentjev, Vladimir S.; Gvozdev, Alexander S.

    2016-01-01

    The paper presents a methodology which helps to avoid a great amount of costly experimental research. This methodology includes thermo-gas dynamic design of an engine and its mounts, the profiling of compressor flow path and cascade design of guide vanes. Employing a method elaborated by Howell, we provide a theoretical solution to the task of…

  11. Idea²market: Implementing an ideation guide for product design education and innovation

    NARCIS (Netherlands)

    De Wit, I.; Du Bois, E.; Moons, I.M.R.; Jacoby, A.

    2012-01-01

    As current design students will be potential moderators for future design ideation sessions, the research focused on an ideation guide to support them in executing these sessions. Nowadays, mapping the number of tools onto the logic of the innovation process gives an overload of possibilities and re

  12. Guided transect sampling - a new design combining prior information and field surveying

    Science.gov (United States)

    Anna Ringvall; Goran Stahl; Tomas Lamas

    2000-01-01

    Guided transect sampling is a two-stage sampling design in which prior information is used to guide the field survey in the second stage. In the first stage, broad strips are randomly selected and divided into grid-cells. For each cell a covariate value is estimated from remote sensing data, for example. The covariate is the basis for subsampling of a transect through...

  13. Design and development of guide vane cascade for a low speed number Francis turbine

    Institute of Scientific and Technical Information of China (English)

    Biraj Singh THAPA; Chirag TRIVEDI; Ole Gunnar DAHLHAUG

    2016-01-01

    Guide vane cascade of a low speed number Francis turbine is developed for the experimental investigations. The test setup is able to produce similar velocity distributions at the runner inlet as that of a reference prototype turbine. Standard analytical methods are used to design the reference turbine. Periodic walls of flow channel between guide vanes are identified as the starting profile for the boundary of the cascade. Two alternative designs with three guide vanes and two guide vanes, without runner, are studied. A new approach, for the hydraulic design and optimization of the cascade test setup layout, is proposed and investigated in details. CFD based optimization methods are used to define the final layout of the test setup. The optimum design is developed as a test setup and experimental validation is done with PIV methods. The optimized design of cascade with one guide vane between two flow channels is found to produce similar flow conditions to that in the runner inlet of a low speed number Francis turbine.

  14. Designing Tracking Software for Image-Guided Surgery Applications: IGSTK Experience.

    Science.gov (United States)

    Enquobahrie, Andinet; Gobbi, David; Turek, Matt; Cheng, Patrick; Yaniv, Ziv; Lindseth, Frank; Cleary, Kevin

    2008-11-01

    OBJECTIVE: Many image-guided surgery applications require tracking devices as part of their core functionality. The Image-Guided Surgery Toolkit (IGSTK) was designed and developed to interface tracking devices with software applications incorporating medical images. METHODS: IGSTK was designed as an open source C++ library that provides the basic components needed for fast prototyping and development of image-guided surgery applications. This library follows a component-based architecture with several components designed for specific sets of image-guided surgery functions. At the core of the toolkit is the tracker component that handles communication between a control computer and navigation device to gather pose measurements of surgical instruments present in the surgical scene. The representations of the tracked instruments are superimposed on anatomical images to provide visual feedback to the clinician during surgical procedures. RESULTS: The initial version of the IGSTK toolkit has been released in the public domain and several trackers are supported. The toolkit and related information are available at www.igstk.org. CONCLUSION: With the increased popularity of minimally invasive procedures in health care, several tracking devices have been developed for medical applications. Designing and implementing high-quality and safe software to handle these different types of trackers in a common framework is a challenging task. It requires establishing key software design principles that emphasize abstraction, extensibility, reusability, fault-tolerance, and portability. IGSTK is an open source library that satisfies these needs for the image-guided surgery community.

  15. Procedural guide for the design of transit stations and terminals

    Energy Technology Data Exchange (ETDEWEB)

    Demetsky, M.J.; Hoel, L.A.; Virkler, M.R.

    1977-06-01

    State-of-the-art concepts regarding the planning, design, and evaluation of passenger transportation stations are discussed. The material directs transportation planning teams to search for efficient station designs. The important stages and considerations in a comprehensive terminal analysis methodology are described. The transit station design process requires contributions from many disciplines and skills. The report given will help coordinate station development programs in accommodating inputs from the disciplines, and it highlights the elements of different stations to assure valid comparisons relative to performance and cost criteria.

  16. Level up! the guide to great video game design

    CERN Document Server

    Rogers, Scott

    2014-01-01

    Want to design your own video games? Let expert Scott Rogers show you how! If you want to design and build cutting-edge video games but aren't sure where to start, then the SECOND EDITION of the acclaimed Level Up! is for you! Written by leading video game expert Scott Rogers, who has designed the hits Pac Man World, Maximo and SpongeBob Squarepants, this updated edition provides clear and well-thought out examples that forgo theoretical gobbledygook with charmingly illustrated concepts and solutions based on years of professional experience. Level Up! 2nd Edition has been NEWLY EXPANDED to

  17. Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design.

    Science.gov (United States)

    Farboud, Behnom; Meyer, Barbara J

    2015-04-01

    Success with genome editing by the RNA-programmed nuclease Cas9 has been limited by the inability to predict effective guide RNAs and DNA target sites. Not all guide RNAs have been successful, and even those that were, varied widely in their efficacy. Here we describe and validate a strategy for Caenorhabditis elegans that reliably achieved a high frequency of genome editing for all targets tested in vivo. The key innovation was to design guide RNAs with a GG motif at the 3' end of their target-specific sequences. All guides designed using this simple principle induced a high frequency of targeted mutagenesis via nonhomologous end joining (NHEJ) and a high frequency of precise DNA integration from exogenous DNA templates via homology-directed repair (HDR). Related guide RNAs having the GG motif shifted by only three nucleotides showed severely reduced or no genome editing. We also combined the 3' GG guide improvement with a co-CRISPR/co-conversion approach. For this co-conversion scheme, animals were only screened for genome editing at designated targets if they exhibited a dominant phenotype caused by Cas9-dependent editing of an unrelated target. Combining the two strategies further enhanced the ease of mutant recovery, thereby providing a powerful means to obtain desired genetic changes in an otherwise unaltered genome. Copyright © 2015 by the Genetics Society of America.

  18. Principles of VLSI RTL design a practical guide

    CERN Document Server

    Churiwala, Sanjay; Gianfagna, Mike

    2011-01-01

    This book examines the impact of register transfer level (RTL) design choices that may result in issues of testability, data synchronization across clock domains, synthesizability, power consumption and routability, that appear later in the product lifecycle.

  19. A quick guide to CRISPR sgRNA design tools

    Science.gov (United States)

    Brazelton, Vincent A; Zarecor, Scott; Wright, David A; Wang, Yuan; Liu, Jie; Chen, Keting; Yang, Bing; Lawrence-Dill, Carolyn J

    2015-01-01

    ABSTRACT Targeted genome editing is now possible in nearly any organism and is widely acknowledged as a biotech game-changer. Among available gene editing techniques, the CRISPR-Cas9 system is the current favorite because it has been shown to work in many species, does not necessarily result in the addition of foreign DNA at the target site, and follows a set of simple design rules for target selection. Use of the CRISPR-Cas9 system is facilitated by the availability of an array of CRISPR design tools that vary in design specifications and parameter choices, available genomes, graphical visualization, and downstream analysis functionality. To help researchers choose a tool that best suits their specific research needs, we review the functionality of various CRISPR design tools including our own, the CRISPR Genome Analysis Tool (CGAT; http://cropbioengineering.iastate.edu/cgat). PMID:26745836

  20. Variation-Aware Design of Custom Integrated Circuits A Hands-on Field Guide A Hands-on Field Guide

    CERN Document Server

    McConaghy, Trent; Dyck, Jeffrey; Gupta, Amit

    2013-01-01

    This book targets custom IC designers who are encountering variation issues in their designs, especially for modern process nodes at 45nm and below, such as statistical process variations, environmental variations, and layout effects.  The authors have created a field guide to show how to handle variation proactively, and to understand the benefits of doing so. Readers facing variation challenges in their memory, standard cell, analog/RF, and custom digital designs will find easy-to-read, pragmatic solutions.   Reviews the most important concepts in variation-aware design, including types of variables and variation, useful variation-aware design terminology, and an overview and comparison of high-level design flows. Describes and compares a suite of approaches and flows for PVT corner-driven design and verification. Presents Fast PVT, a novel, confidence-driven global optimization technique for PVT corner extraction and verification that is both rapid and reliable. Presents a visually-oriented overview of ...

  1. Guided exploration of physically valid shapes for furniture design

    KAUST Repository

    Umetani, Nobuyuki

    2012-07-01

    Geometric modeling and the physical validity of shapes are traditionally considered independently. This makes creating aesthetically pleasing yet physically valid models challenging. We propose an interactive design framework for efficient and intuitive exploration of geometrically and physically valid shapes. During any geometric editing operation, the proposed system continuously visualizes the valid range of the parameter being edited. When one or more constraints are violated after an operation, the system generates multiple suggestions involving both discrete and continuous changes to restore validity. Each suggestion also comes with an editing mode that simultaneously adjusts multiple parameters in a coordinated way to maintain validity. Thus, while the user focuses on the aesthetic aspects of the design, our computational design framework helps to achieve physical realizability by providing active guidance to the user. We demonstrate our framework on plankbased furniture design with nail-joint and frictional constraints. We use our system to design a range of examples, conduct a user study, and also fabricate a physical prototype to test the validity and usefulness of the system. © 2012 ACM 0730-0301/2012/08- ART86.

  2. GIS cartography a guide to effective map design

    CERN Document Server

    Peterson, Gretchen N

    2014-01-01

    IntroductionOn Design ExperienceConstructive CriticismWhat Is a Geoprofessional?Tick-Tock Goes the ClockWhy Good Design MattersAudienceHow to Use This BookSkipping the How-Tos to Get Straight to the Good StuffRelative Map ScalesEndnotesCreative InspirationYou Can Be CreativeDoingSeeingAn Example of How to SeeApplying All of This to Your MapSummary and Final ProddingCreative MapsA Few Places to Start Seeing Art from Your DesktopEndnotesExerciseLayout DesignAll Together NowLayout ChecklistElement Details and ExamplesStyleContextArrangementEmphasis Maps and WireframesSimplicity versus ComplexityM

  3. Mechanical System Analysis/Design Tool (MSAT) Quick Guide

    Science.gov (United States)

    Lee, HauHua; Kolb, Mark; Madelone, Jack

    1998-01-01

    MSAT is a unique multi-component multi-disciplinary tool that organizes design analysis tasks around object-oriented representations of configuration components, analysis programs and modules, and data transfer links between them. This creative modular architecture enables rapid generation of input stream for trade-off studies of various engine configurations. The data transfer links automatically transport output from one application as relevant input to the next application once the sequence is set up by the user. The computations are managed via constraint propagation - the constraints supplied by the user as part of any optimization module. The software can be used in the preliminary design stage as well as during the detail design of product development process.

  4. Best Practices Guide for Energy-Efficient Data Center Design: Revised March 2011 (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2011-03-01

    This guide provides an overview of best practices for energy-efficient data center design which spans the categories of Information Technology (IT) systems and their environmental conditions, data center air management, cooling and electrical systems, on-site generation, and heat recovery. IT system energy efficiency and environmental conditions are presented first because measures taken in these areas have a cascading effect of secondary energy savings for the mechanical and electrical systems. This guide concludes with a section on metrics and benchmarking values by which a data center and its systems energy efficiency can be evaluated. No design guide can offer 'the most energy-efficient' data center design but the guidelines that follow offer suggestions that provide efficiency benefits for a wide variety of data center scenarios.

  5. Making maps a visual guide to map design for GIS

    CERN Document Server

    Krygier, John

    2016-01-01

    Lauded for its accessibility and beautiful design, this text has given thousands of students and professionals the tools to create effective, compelling maps. Using a wealth of illustrations--with 74 in full color--to elucidate each concisely presented point, the revised and updated third edition continues to emphasize how design choices relate to the reasons for making a map and its intended purpose. All components of map making are covered: titles, labels, legends, visual hierarchy, font selection, how to turn phenomena into visual data, data organization, symbolization, and more. Innovative

  6. Geomatics engineering a practical guide to project design

    CERN Document Server

    Ogaja, Clement A

    2010-01-01

    OVERVIEWProject Design ProcessUnderstanding Project RequirementsInformation GatheringDesign ApproachesScheduling and Cost EstimatingWriting ProposalsBibliographyExercises CONTEMPORARY ISSUESStandards and SpecificationsDefinitionsApplication Modes of a StandardUnits of MeasureAccuracy versus PrecisionEquipment SpecificationsLimits of ClosureLeast Squares AnalysisMapping and GIS StandardsClassical Surveying StandardsGPS Surveying StandardsOther StandardsBibliography ExercisesProfessional and Ethical ResponsibilitiesKnow What You DoEthics and Professional Conduct Individual and Team Responsibilit

  7. S-polarized nonlinear surface and guided waves in an asymmetric layered structure

    Energy Technology Data Exchange (ETDEWEB)

    Mihalache, D.; Totia, H.

    1983-08-01

    An exact solution of Maxwell's equations is found, corresponding to s-polarized nonlinear surface and guided waves in an asymmetric layered structure. The system under consideration consists of a film with dielectric constant epsilon/sub 2/ bounded at the negative-z side by a linear medium with dielectric constant epsilon/sub 1/ and at the positive -z side by a nonlinear substrate characterized by the diagonal dielectric tensor epsilon/sub 11/ = epsilon/sub 22/ = epsilon/sub 33/ = epsilon/sub 0/ + ..cap alpha.. absolute value of E-vector/sup 2/, ..cap alpha.. > 0 (a selffocussing medium). We predict bistable states of s-polarized nonlinear surface and guided waves provided that the power flow in the wave is the control parameter.

  8. Remote Maintenance Design Guide for Compact Processing Units

    Energy Technology Data Exchange (ETDEWEB)

    Draper, J.V.

    2000-07-13

    Oak Ridge National Laboratory (ORNL) Robotics and Process Systems (RPSD) personnel have extensive experience working with remotely operated and maintained systems. These systems require expert knowledge in teleoperation, human factors, telerobotics, and other robotic devices so that remote equipment may be manipulated, operated, serviced, surveyed, and moved about in a hazardous environment. The RPSD staff has a wealth of experience in this area, including knowledge in the broad topics of human factors, modular electronics, modular mechanical systems, hardware design, and specialized tooling. Examples of projects that illustrate and highlight RPSD's unique experience in remote systems design and application include the following: (1) design of a remote shear and remote dissolver systems in support of U.S. Department of Energy (DOE) fuel recycling research and nuclear power missions; (2) building remotely operated mobile systems for metrology and characterizing hazardous facilities in support of remote operations within those facilities; (3) construction of modular robotic arms, including the Laboratory Telerobotic Manipulator, which was designed for the National Aeronautics and Space Administration (NASA) and the Advanced ServoManipulator, which was designed for the DOE; (4) design of remotely operated laboratories, including chemical analysis and biochemical processing laboratories; (5) construction of remote systems for environmental clean up and characterization, including underwater, buried waste, underground storage tank (UST) and decontamination and dismantlement (D&D) applications. Remote maintenance has played a significant role in fuel reprocessing because of combined chemical and radiological contamination. Furthermore, remote maintenance is expected to play a strong role in future waste remediation. The compact processing units (CPUs) being designed for use in underground waste storage tank remediation are examples of improvements in systems

  9. Lossless directional guiding of light in dielectric nanosheets using Dyakonov surface waves.

    Science.gov (United States)

    Takayama, Osamu; Artigas, David; Torner, Lluis

    2014-06-01

    Guiding light at the nanoscale is usually accomplished using surface plasmons. However, plasmons propagating at the surface of a metal sustain propagation losses. A different type of surface excitation is the Dyakonov surface wave. These waves, which exist in lossless media, were predicted more than two decades ago but observed only recently. Dyakonov surface waves exist when at least one of the two media forming the surface exhibits a suitable anisotropy of refractive indexes. Although propagating only within a narrow range of directions, these waves can be used to create modes supported by ultrathin films that confine light efficiently within film thicknesses well below the cutoff thickness required in standard waveguides. Here, we show that 10 nm and 20 nm dielectric nanosheets of aluminium oxide clad between an anisotropic crystal (lithium triborate) and different liquids support Dyakonov-like modes. The direction of light propagation can be controlled by modulating the refractive index of the cladding. The possibility of guiding light in nanometre-thick films with no losses and high directionality makes Dyakonov wave modes attractive for planar photonic devices in schemes similar to those currently employing long-range plasmons.

  10. Facet‐Engineered Surface and Interface Design of Photocatalytic Materials

    Science.gov (United States)

    Wang, Lili; Li, Zhengquan

    2016-01-01

    The facet‐engineered surface and interface design for photocatalytic materials has been proven as a versatile approach to enhance their photocatalytic performance. This review article encompasses some recent advances in the facet engineering that has been performed to control the surface of mono‐component semiconductor systems and to design the surface and interface structures of multi‐component heterostructures toward photocatalytic applications. The review begins with some key points which should receive attention in the facet engineering on photocatalytic materials. We then discuss the synthetic approaches to achieve the facet control associated with the surface and interface design. In the following section, the facet‐engineered surface design on mono‐component photocatalytic materials is introduced, which forms a basis for the discussion on more complex systems. Subsequently, we elucidate the facet‐engineered surface and interface design of multi‐component photocatalytic materials. Finally, the existing challenges and future prospects are discussed. PMID:28105398

  11. Facet-Engineered Surface and Interface Design of Photocatalytic Materials.

    Science.gov (United States)

    Bai, Song; Wang, Lili; Li, Zhengquan; Xiong, Yujie

    2017-01-01

    The facet-engineered surface and interface design for photocatalytic materials has been proven as a versatile approach to enhance their photocatalytic performance. This review article encompasses some recent advances in the facet engineering that has been performed to control the surface of mono-component semiconductor systems and to design the surface and interface structures of multi-component heterostructures toward photocatalytic applications. The review begins with some key points which should receive attention in the facet engineering on photocatalytic materials. We then discuss the synthetic approaches to achieve the facet control associated with the surface and interface design. In the following section, the facet-engineered surface design on mono-component photocatalytic materials is introduced, which forms a basis for the discussion on more complex systems. Subsequently, we elucidate the facet-engineered surface and interface design of multi-component photocatalytic materials. Finally, the existing challenges and future prospects are discussed.

  12. Towards Clinically Optimized MRI-guided Surgical Manipulator for Minimally Invasive Prostate Percutaneous Interventions: Constructive Design*

    OpenAIRE

    Eslami, Sohrab; Fischer, Gregory S.; Song, Sang-Eun; Tokuda, Junichi; Hata, Nobuhiko; Tempany, Clare M.; Iordachita, Iulian

    2013-01-01

    This paper undertakes the modular design and development of a minimally invasive surgical manipulator for MRI-guided transperineal prostate interventions. Severe constraints for the MRI-compatibility to hold the minimum artifact on the image quality and dimensions restraint of the bore scanner shadow the design procedure. Regarding the constructive design, the manipulator kinematics has been optimized and the effective analytical needle workspace is developed and followed by proposing the wor...

  13. School Boarding Accommodation. A Design Guide. Building Bulletin 84.

    Science.gov (United States)

    Wilson, Jeremy; Lloyd-Jones, Liz; Carden, Tom; Daniels, Richard; Fitzgerald, Brian; Maddick, Jenny

    This bulletin contains on-statutory guidance describing good practice and its implications for boarding accommodation to assist those responsible for briefing and designing boarding accommodations across all school sectors. It offers practical advice and illustrates examples that reflect changes in provision which are thought to be acceptable and…

  14. A Short Guide to Experimental Design and Analysis for Engineers

    Science.gov (United States)

    2014-04-01

    study of women’s ratings of men based on masculinity , Frederick and Haselton had participants performing octuple duty – providing ratings of...et al. (2012) CK-12 Middle School Math Grade 6. Vol. 1, CK-12 Foundation Mitchell, M. L. and Jolley, J. M. (2010) Research Design Explained. 7th ed

  15. The unofficial guide for authors : from research design to publication

    NARCIS (Netherlands)

    Hengl, T.; Gould, M.; Gerritsma, W.

    2011-01-01

    Most scientific journals provide guidelines for authors - how to format references and prepare artwork, how many copies of the paper to submit and to which address. However, most official guidelines say little about how you should design and produce your paper and the chances that it will be accepte

  16. Mixing Ventilation. Guide on mixing air distribution design

    DEFF Research Database (Denmark)

    Kandzia, Claudia; Kosonen, Risto; Melikov, Arsen Krikor

    In this guidebook most of the known and used in practice methods for achieving mixing air distribution are discussed. Mixing ventilation has been applied to many different spaces providing fresh air and thermal comfort to the occupants. Today, a design engineer can choose from large selection...... of air diffusers and exhaust openings....

  17. Mixing ventilation guide on mixing air distribution design

    CERN Document Server

    Kandzia, Claudia; Kosonen, Risto; Krikor Melikov, Arsen; Nielsen, Peter Vilhelm

    2013-01-01

    In this guidebook most of the known and used in practice methods for achieving mixing air distribution are discussed. Mixing ventilation has been applied to many different spaces providing fresh air and thermal comfort to the occupants. Today, a design engineer can choose from large selection of air diffusers and exhaust openings.

  18. The designer's guide to jitter in ring oscillators

    CERN Document Server

    McNeill, John A

    2009-01-01

    Emphasizes jitter for time domain applications so that there is not a need to translate from frequency domain. This book includes classification of oscillator types. It is suitable for practicing designers with BS or MS degrees and researchers working in fields where noise requirements are specified in the time domain.

  19. A Prospective Method to Guide Small Molecule Drug Design

    Science.gov (United States)

    Johnson, Alan T.

    2015-01-01

    At present, small molecule drug design follows a retrospective path when considering what analogs are to be made around a current hit or lead molecule with the focus often on identifying a compound with higher intrinsic potency. What this approach overlooks is the simultaneous need to also improve the physicochemical (PC) and pharmacokinetic (PK)…

  20. Comparison of connective tissue graft and guided tissue regeneration in covering root surfaces

    OpenAIRE

    LotfazarM.; Faghihi Sh.

    2002-01-01

    There are many researches evaluation different methods for covering the root surface. In the most of these studies, type I and II of Miller treatment had been searched. The purpose of this study was a comparison between connective tissue graft (CTG) and guided tissue regeneration (GTR) with a collagen membrane in the treatment of gingival recession defects (Miller class III). Six patients, each contributing a pair of Miller class III buccal gingival recessions, were treated. The clinical meas...

  1. Design and numerical simulations of the GMT Natural Guide star WFS

    Science.gov (United States)

    Pinna, E.; Agapito, G.; Quirós-Pacheco, F.; Antichi, J.; Carbonaro, L.; Briguglio, R.; Bonaglia, M.; Riccardi, A.; Puglisi, A.; Biliotti, V.; Arcidiacono, C.; Xompero, M.; Di Rico, G.; Valentini, A.; Bouchez, A.; Santoro, F.; Trancho, G.; Esposito, S.

    2014-08-01

    The NGSAO, a single conjugated AO system operating with natural guide star, will be the first AO system to be operative at the Giant Magellan Telescope. The Natural Guide star Wavefront Sensor will be in charge of the entire wavefront error measurement, namely atmospheric turbulence and telescope aberrations, including the segment differential piston error. In this paper we report the opto-mechanical design of the NGWS that successfully passed the preliminary design review in July 2013. Moreover, we present the NGSAO control strategy identified for the GMT segmented pupil and the system performances for different conditions of seeing and reference star magnitude.

  2. Guide to radiological accident considerations for siting and design of DOE nonreactor nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Elder, J.C.; Graf, J.M.; Dewart, J.M.; Buhl, T.E.; Wenzel, W.J.; Walker, L.J.; Stoker, A.K.

    1986-01-01

    This guide was prepared to provide the experienced safety analyst with accident analysis guidance in greater detail than is possible in Department of Energy (DOE) Orders. The guide addresses analysis of postulated serious accidents considered in the siting and selection of major design features of DOE nuclear facilities. Its scope has been limited to radiological accidents at nonreactor nuclear facilities. The analysis steps addressed in the guide lead to evaluation of radiological dose to exposed persons for comparison with siting guideline doses. Other possible consequences considered are environmental contamination, population dose, and public health effects. Choices of models and parameters leading to estimation of source terms, release fractions, reduction and removal factors, dispersion and dose factors are discussed. Although requirements for risk analysis have not been established, risk estimates are finding increased use in siting of major nuclear facilities, and are discussed in the guide. 3 figs., 9 tabs.

  3. MHTool User's Guide - Software for Manufactured Housing Structural Design

    Energy Technology Data Exchange (ETDEWEB)

    W. D. Richins

    2005-07-01

    Since the late 1990s, the Department of Energy's Idaho National Laboratory (INL) has worked with the US Department of Housing and Urban Development (HUD), the Manufactured Housing Institute (MHI), the National Institute of Standards and Technology (NIST), the National Science Foundation (NSF), and an industry committee to measure the response of manufactured housing to both artificial and natural wind loads and to develop a computational desktop tool to optimize the structural performance of manufactured housing to HUD Code loads. MHTool is the result of an 8-year intensive testing and verification effort using single and double section homes. MHTool is the first fully integrated structural analysis software package specifically designed for manufactured housing. To use MHTool, industry design engineers will enter information (geometries, materials, connection types, etc.) describing the structure of a manufactured home, creating a base model. Windows, doors, and interior walls can be added to the initial design. Engineers will input the loads required by the HUD Code (wind, snow loads, interior live loads, etc.) and run an embedded finite element solver to find walls or connections where stresses are either excessive or very low. The designer could, for example, substitute a less expensive and easier to install connection in areas with very low stress, then re-run the analysis for verification. If forces and stresses are still within HUD Code requirements, construction costs would be saved without sacrificing quality. Manufacturers can easily change geometries or component properties to optimize designs of various floor plans then submit MHTool input and output in place of calculations for DAPIA review. No change in the regulatory process is anticipated. MHTool, while not yet complete, is now ready for demonstration. The pre-BETA version (Build-16) was displayed at the 2005 National Congress & Expo for Manufactured & Modular Housing. Additional base models

  4. Fabrication of multifaceted, micropatterned surfaces and image-guided patterning using laser scanning lithography.

    Science.gov (United States)

    Slater, John H; West, Jennifer L

    2014-01-01

    This protocol describes the implementation of laser scanning lithography (LSL) for the fabrication of multifaceted, patterned surfaces and for image-guided patterning. This photothermal-based patterning technique allows for selective removal of desired regions of an alkanethiol self-assembled monolayer on a metal film through raster scanning a focused 532 nm laser using a commercially available laser scanning confocal microscope. Unlike traditional photolithography methods, this technique does not require the use of a physical master and instead utilizes digital "virtual masks" that can be modified "on the fly" allowing for quick pattern modifications. The process to create multifaceted, micropatterned surfaces, surfaces that display pattern arrays of multiple biomolecules with each molecule confined to its own array, is described in detail. The generation of pattern configurations from user-chosen images, image-guided LSL is also described. This protocol outlines LSL in four basic sections. The first section details substrate preparation and includes cleaning of glass coverslips, metal deposition, and alkanethiol functionalization. The second section describes two ways to define pattern configurations, the first through manual input of pattern coordinates and dimensions using Zeiss AIM software and the second via image-guided pattern generation using a custom-written MATLAB script. The third section describes the details of the patterning procedure and postpatterning functionalization with an alkanethiol, protein, and both, and the fourth section covers cell seeding and culture. We end with a general discussion concerning the pitfalls of LSL and present potential improvements that can be made to the technique.

  5. 78 FR 31614 - Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles

    Science.gov (United States)

    2013-05-24

    ....221 on Design-Basis Hurricane and Hurricane Missiles AGENCY: Nuclear Regulatory Commission. ACTION... guidance regarding the application of Regulatory Guide (RG) 1.221, ``Design-Basis Hurricane and Hurricane... ML13015A688 Interim Staff Guidance-024 on Implementation of Regulatory Guide 1.221 on Design-Basis...

  6. 77 FR 64564 - Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles

    Science.gov (United States)

    2012-10-22

    ... COMMISSION Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles AGENCY....221 on Design-Basis Hurricane and Hurricane Missiles.'' The purpose of this ISG is to supplement the guidance regarding the application of Regulatory Guide 1.221, ``Design-Basis Hurricane and...

  7. Optical design of the adaptive optics laser guide star system

    Energy Technology Data Exchange (ETDEWEB)

    Bissinger, H. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    The design of an adaptive optics package for the 3 meter Lick telescope is presented. This instrument package includes a 69 actuator deformable mirror and a Hartmann type wavefront sensor operating in the visible wavelength; a quadrant detector for the tip-tile sensor and a tip-tilt mirror to stabilize atmospheric first order tip-tile errors. A high speed computer drives the deformable mirror to achieve near diffraction limited imagery. The different optical components and their individual design constraints are described. motorized stages and diagnostics tools are used to operate and maintain alignment throughout observation time from a remote control room. The expected performance are summarized and actual results of astronomical sources are presented.

  8. Library Design Guided by In-house Developed Computer Tools

    Institute of Scientific and Technical Information of China (English)

    LI Ge

    2001-01-01

    @@ In recent years, combinatorial library synthesis for drug discovery begins to migrate from library synthesis solely dictated by chemistry availability to design and synthesis of libraries with more drug-like properties. Lipinski's rule of five has been used to evaluate drug-like properties of individual compound; recently LibProTM, a new computation program has been developed at Pharmacopeia to evaluate durg-like properties of libraries. By using LibPrpTM, chemists at Pharmacopeia are able to obtain information of molecular weight and ClogP distribution of a library, and percentage of library members that violate Lipinski's rule after input structures of synthons for each combinatorial step. Currently, a "virtual library design” approach that is to calculate properties of a library at conceptual phase of the library design has been used to predetermine the value of the library. Also a new computer program used to predict "Absorption” of compounds will also be discussed.

  9. Design of Engineering Surfaces Using Quartic Parabolas

    Science.gov (United States)

    Chekalin, A. A.; Reshetnikov, M. K.; Shpilev, V. V.; Borodulina, S. V.

    2017-07-01

    The article considers the wireframe-kinematic method of hydrodynamic simulation of surfaces presented by the example of marine craft’s bottom structure. The motion trajectory for the variable shape generator is normally set by a single or a number of directing lines. The law of shape variations of the generator is represented by the graphical or analytical display, or by a set of directing lines. All of these make up the so-called determinant of the surface, which includes the geometry component, or a certain initial position of the generator, and the algorithm component, i.e. the algorithm of the wireframe sealing. The directing line may be simple, described by a single equation, or compsite piecewise-smooth. In this situation, they are commonly modelled using splines, which results in piecewise-smooth surfaces.

  10. Making maps a visual guide to map design for GIS

    CERN Document Server

    Krygier, John

    2011-01-01

    Acclaimed for its innovative use of visual material, this book is engaging, clear, and compelling-exactly how an effective map should be. Nearly every page is organized around maps and other figures (many in full color) that illustrate all aspects of map making, including instructive examples of both good and poor design choices. The book covers everything from locating and processing data to making decisions about layout, symbols, color, and type. Readers are invited to think critically about both the technical features and social significance of maps as they learn to create better maps of t

  11. Using QA classification to guide design and manage risk

    Energy Technology Data Exchange (ETDEWEB)

    Lathrop, J. [Strategic Insights, Los Altos, CA (United States); DeKlever, R. [Raytheon Services Nevada, Las Vegas, NV (United States); Petrie, E.H. [USDOE Nevada Field Office, Las Vegas, NV (United States)

    1993-01-28

    Raytheon Services Nevada has developed a classification process based on probabilistic risk assessment, using accident/impact scenarios for each system classified. Initial classification analyses were performed for the 20 systems of Package IA of the Exploratory Studies Facility (ESF). The analyses demonstrated a solid, defensible methodological basis for classification which minimizes the use of direct engineering judgment. They provide guidance for ESF design and risk management through the identification of: The critical characteristics of each system that need to be controlled; and the parts of the information base that most need to be further developed through performance assessment or other efforts.

  12. Design guide for single circular cylinder in turbulent crossflow. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Mulcahy, T.M.

    1982-03-01

    A design procedure is proposed for predicting the dynamic structural response of a circular cylinder in turbulent crossflow. The procedure is based on recently obtained data for a stationary, rigid cylinder and on existing information. The procedure is not applicable to conditions where the wake vortex shedding frequency locks into a structural natural frequency. This report is self-contained in that all the information and structural analysis methods employed in the procedure are reviewed and developed. Also, an example is given to illustrate the use of the method for a typical reactor component. The calculated responses are found to be very small.

  13. Google SketchUp for Game Design Beginner's Guide

    CERN Document Server

    de Jongh, Robin

    2011-01-01

    The book takes a clear, step-by-step approach to building a complete game level using SketchUp with many props and textures. This book is designed for anyone who wants to create entire 3D worlds in freely available game engines such as Unity 3D, CryEngine, Ogre, Panda3D, Unreal Engine, and Blender Game Engine. It also targets all those who wish to create new levels and assets to sell in game asset stores or use in visualization or animation.

  14. Design of Guided Air Ammunition's Optimal Guidance Law

    Institute of Scientific and Technical Information of China (English)

    LIU Min; LIU Zao-zhen; WANG Bao-cheng

    2005-01-01

    Some long distance air ammunition can be used to attack large still target. According to this character and according to the mathematical description of target-missile relative motion built by the message supplied by the strapdown inertial navigation system/global position system (SINS/GPS) of air ammunition, optimal guidance law is designed by applying optimal control theory. The simulation is provided to indicate that when the air ammunition reaches the target, its line-of-sight (LOS) and LOS angular rate can nearly equal zero. So the air ammunition can get good terminal attitude, and the air ammunition reaches the target at the expected velocity and heading.

  15. A Settlers’ Guide: Designing for Resilience in the Hinterlands

    Directory of Open Access Journals (Sweden)

    Martin Bryant

    2017-03-01

    Full Text Available There has often been a mutually beneficial relationship between cities and their rural hinterlands. The Kapiti region outside the city of Wellington in New Zealand is a prime example: it once provided Wellington’s food, water and cultural diversity for both Māori and European settlers. However, productivity-driven agriculture and extensive dormitory-suburbanization have affected significant parts of this once-abundant hinterland. Food production is becoming more mono-cultural, water quality is degrading, ecosystems’ biodiversity is disappearing, provincial town centres are shrinking, emigrating youth are leaving unbalanced demographics, Māori are increasingly disassociating their culture from their traditional lands and natural disasters are causing more impact—all of which is making Kapiti less resilient, and severing the once-healthy city-hinterland relationship. Our work on future settlement opportunities in Kapiti proposes alternatives, using experimental design-led research methods to develop speculative architectural and landscape architectural schemes. The schemes are framed by some of the spatial attributes of resilience: diversity, complexity, redundancy, interconnectivity and adaptability. Collectively, the work reveals design strategies that have a potential to rebuild hinterlands’ culture, town centres, housing, agriculture, community and ecosystems and to recalibrate the broader relationship between hinterlands and metropolitan systems.

  16. ARM System Developer's Guide Designing and Optimizing System Software

    CERN Document Server

    Sloss, Andrew

    2004-01-01

    Over the last ten years, the ARM architecture has become one of the most pervasive architectures in the world, with more than 2 billion ARM-based processors embedded in products ranging from cell phones to automotive braking systems. A world-wide community of ARM developers in semiconductor and product design companies includes software developers, system designers and hardware engineers. To date no book has directly addressed their need to develop the system and software for an ARM-based system. This text fills that gap. This book provides a comprehensive description of the operation of the ARM core from a developer's perspective with a clear emphasis on software. It demonstrates not only how to write efficient ARM software in C and assembly but also how to optimize code. Example code throughout the book can be integrated into commercial products or used as templates to enable quick creation of productive software. The book covers both the ARM and Thumb instruction sets, covers Intel''s XScale Processors, ou...

  17. Library Design Guided by In-house Developed Computer Tools

    Institute of Scientific and Technical Information of China (English)

    LI; Ge

    2001-01-01

    In recent years, combinatorial library synthesis for drug discovery begins to migrate from library synthesis solely dictated by chemistry availability to design and synthesis of libraries with more drug-like properties. Lipinski's rule of five has been used to evaluate drug-like properties of individual compound; recently LibProTM, a new computation program has been developed at Pharmacopeia to evaluate durg-like properties of libraries. By using LibPrpTM, chemists at Pharmacopeia are able to obtain information of molecular weight and ClogP distribution of a library, and percentage of library members that violate Lipinski's rule after input structures of synthons for each combinatorial step. Currently, a "virtual library design” approach that is to calculate properties of a library at conceptual phase of the library design has been used to predetermine the value of the library. Also a new computer program used to predict "Absorption” of compounds will also be discussed.  ……

  18. Technical Support Document: The Development of the Advanced Energy Design Guide for Highway Lodging Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Wei; Jarnagin, Ronald E.; Gowri, Krishnan; McBride, M.; Liu, Bing

    2008-09-30

    This Technical Support Document (TSD) describes the process and methodology for development of the Advanced Energy Design Guide for Highway Lodgings (AEDG-HL or the Guide), a design guidance document intended to provide recommendations for achieving 30% energy savings in highway lodging properties over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The AEDG-HL is the fifth in a series of guides being developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc. (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA), the United States Green Buildings Council (USGBC), and the U.S. Department of Energy (DOE).

  19. Removal of Supernumerary Teeth Utilizing a Computer-Aided Design/Computer-Aided Manufacturing Surgical Guide.

    Science.gov (United States)

    Jo, Chanwoo; Bae, Doohwan; Choi, Byungho; Kim, Jihun

    2017-05-01

    Supernumerary teeth need to be removed because they can cause various complications. Caution is needed because their removal can cause damage to permanent teeth or tooth germs in the local vicinity. Surgical guides have recently been used in maxillofacial surgery. Because surgical guides are designed through preoperative analysis by computer-aided design software and fabricated using a 3-dimensional printer applying computer-aided manufacturing technology, they increase the accuracy and predictability of surgery. This report describes 2 cases of removal of a mesiodens-1 from a child and 1 from an adolescent-using a surgical guide; these would have been difficult to remove with conventional surgical methods. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  20. Designing Solutions using Response Surface Technique

    Directory of Open Access Journals (Sweden)

    COMAN Ovidiu

    2014-05-01

    Full Text Available In the present study a design of experiments method was used to obtain the most suitable responses. The variables that occur in the optimization are the movement of a dielectric material on Oy and Oz axis of a waveguide and the microwave power. The responses refer to the thermal field distribution, the reflected power, dielectric's temperature and the absorbed power.

  1. The Impact of Visual Guided Order Picking on Ocular Comfort, Ocular Surface and Tear Function.

    Directory of Open Access Journals (Sweden)

    Angelika Klein-Theyer

    Full Text Available We investigated the effects of a visual picking system on ocular comfort, the ocular surface and tear function compared to those of a voice guided picking solution.Prospective, observational, cohort study.Institutional.A total of 25 young asymptomatic volunteers performed commissioning over 10 hours on two consecutive days.The operators were guided in the picking process by two different picking solutions, either visually or by voice while their subjective symptoms and ocular surface and tear function parameters were recorded.The visual analogue scale (VAS values, according to subjective dry eye symptoms, in the visual condition were significantly higher at the end of the commissioning than the baseline measurements. In the voice condition, the VAS values remained stable during the commissioning. The tear break-up time (BUT values declined significantly in the visual condition (pre-task: 16.6 sec and post-task: 9.6 sec in the right eyes, that were exposed to the displays, the left eyes in the visual condition showed only a minor decline, whereas the BUT values in the voice condition remained constant (right eyes or even increased (left eyes over the time. No significant differences in the tear meniscus height values before and after the commissioning were observed in either condition.In our study, the use of visually guided picking solutions was correlated with post-task subjective symptoms and tear film instability.

  2. Effect of Surface Pore Structure of Nerve Guide Conduit on Peripheral Nerve Regeneration

    Science.gov (United States)

    Oh, Se Heang; Kim, Jin Rae; Kwon, Gu Birm; Namgung, Uk; Song, Kyu Sang

    2013-01-01

    Polycaprolactone (PCL)/Pluronic F127 nerve guide conduits (NGCs) with different surface pore structures (nano-porous inner surface vs. micro-porous inner surface) but similar physical and chemical properties were fabricated by rolling the opposite side of asymmetrically porous PCL/F127 membranes. The effect of the pore structure on peripheral nerve regeneration through the NGCs was investigated using a sciatic nerve defect model of rats. The nerve fibers and tissues were shown to have regenerated along the longitudinal direction through the NGC with a nano-porous inner surface (Nanopore NGC), while they grew toward the porous wall of the NGC with a micro-porous inner surface (Micropore NGC) and, thus, their growth was restricted when compared with the Nanopore NGC, as investigated by immunohistochemical evaluations (by fluorescence microscopy with anti-neurofilament staining and Hoechst staining for growth pattern of nerve fibers), histological evaluations (by light microscopy with Meyer's modified trichrome staining and Toluidine blue staining and transmission electron microscopy for the regeneration of axon and myelin sheath), and FluoroGold retrograde tracing (for reconnection between proximal and distal stumps). The effect of nerve growth factor (NGF) immobilized on the pore surfaces of the NGCs on nerve regeneration was not so significant when compared with NGCs not containing immobilized NGF. The NGC system with different surface pore structures but the same chemical/physical properties seems to be a good tool that is used for elucidating the surface pore effect of NGCs on nerve regeneration. PMID:22871377

  3. Effect of surface pore structure of nerve guide conduit on peripheral nerve regeneration.

    Science.gov (United States)

    Oh, Se Heang; Kim, Jin Rae; Kwon, Gu Birm; Namgung, Uk; Song, Kyu Sang; Lee, Jin Ho

    2013-03-01

    Polycaprolactone (PCL)/Pluronic F127 nerve guide conduits (NGCs) with different surface pore structures (nano-porous inner surface vs. micro-porous inner surface) but similar physical and chemical properties were fabricated by rolling the opposite side of asymmetrically porous PCL/F127 membranes. The effect of the pore structure on peripheral nerve regeneration through the NGCs was investigated using a sciatic nerve defect model of rats. The nerve fibers and tissues were shown to have regenerated along the longitudinal direction through the NGC with a nano-porous inner surface (Nanopore NGC), while they grew toward the porous wall of the NGC with a micro-porous inner surface (Micropore NGC) and, thus, their growth was restricted when compared with the Nanopore NGC, as investigated by immunohistochemical evaluations (by fluorescence microscopy with anti-neurofilament staining and Hoechst staining for growth pattern of nerve fibers), histological evaluations (by light microscopy with Meyer's modified trichrome staining and Toluidine blue staining and transmission electron microscopy for the regeneration of axon and myelin sheath), and FluoroGold retrograde tracing (for reconnection between proximal and distal stumps). The effect of nerve growth factor (NGF) immobilized on the pore surfaces of the NGCs on nerve regeneration was not so significant when compared with NGCs not containing immobilized NGF. The NGC system with different surface pore structures but the same chemical/physical properties seems to be a good tool that is used for elucidating the surface pore effect of NGCs on nerve regeneration.

  4. Guided-Inquiry Labs Using Bean Beetles for Teaching the Scientific Method & Experimental Design

    Science.gov (United States)

    Schlueter, Mark A.; D'Costa, Allison R.

    2013-01-01

    Guided-inquiry lab activities with bean beetles ("Callosobruchus maculatus") teach students how to develop hypotheses, design experiments, identify experimental variables, collect and interpret data, and formulate conclusions. These activities provide students with real hands-on experiences and skills that reinforce their understanding of the…

  5. Fail-safe design and analysis for the guide vane of a hydro turbine

    Directory of Open Access Journals (Sweden)

    Bentang Arief Budiman

    2016-07-01

    Full Text Available A design for the fail-safe mechanism of a guide vane in a Francis-type hydro turbine is proposed and analyzed. The mechanism that is based on a shear pin as a sacrificial component was designed to remain simple. Unlike the requirements of conventional designs, a shear pin must be able to withstand static and dynamic loads but must fail under a certain overload that could damage a guide vane. An accurate load determination and selection of the shear pin material were demonstrated. The static load for various opening angles of the guide vane were calculated using the computational fluid dynamics Fluent and finite element method Ansys programs. Furthermore, simulations for overload and dynamic load due to the waterhammer phenomenon were also conducted. The results of load calculations were used to select an appropriate shear pin material. Quasi-static shear tests were performed for two shear pins of aluminum alloy Al2024 subjected to different aging treatments (i.e. artificial and natural aging. The test results indicated that the Al2024 treated by natural aging is an appropriate material for a shear pin designed to function as a fail-safe mechanism for the guide vanes of a Francis-type hydro turbine.

  6. Using the DSAP Framework to Guide Instructional Design and Technology Integration in BYOD Classrooms

    Science.gov (United States)

    Wasko, Christopher W.

    2016-01-01

    The purpose of this study was to determine the suitability of the DSAP Framework to guide instructional design and technology integration for teachers piloting a BYOD (Bring Your Own Device) initiative and to measure the impact the initiative had on the amount and type of technology used in pilot classrooms. Quantitative and qualitative data were…

  7. Using the DSAP Framework to Guide Instructional Design and Technology Integration in BYOD Classrooms

    Science.gov (United States)

    Wasko, Christopher W.

    2016-01-01

    The purpose of this study was to determine the suitability of the DSAP Framework to guide instructional design and technology integration for teachers piloting a BYOD (Bring Your Own Device) initiative and to measure the impact the initiative had on the amount and type of technology used in pilot classrooms. Quantitative and qualitative data were…

  8. Designation as a Receiving Institution in the BC Transfer Guide: Policy and Process

    Science.gov (United States)

    British Columbia Council on Admissions and Transfer, 2008

    2008-01-01

    The Recalibrating the British Columbia (BC) Transfer System project initiated in 2005 proposed that the designation of institutions in the BC Transfer Guide as either "sending institution" or "receiving institution," according to their perceived primary function, should be examined. The results of the consultation indicated…

  9. School Health Services: A Facility Planning and Design Guide for School Systems.

    Science.gov (United States)

    Maryland State Dept. of Education, Baltimore.

    This guide for Maryland schools outlines the role of school health services and proper facility design for these services. Chapter 1 provides an overview, describing coordinated school health programs, school health services programs, school health services programs in Maryland, how school health services are delivered, trends, the number of…

  10. Design, durability and low cost processing technology for composite fan exit guide vanes

    Science.gov (United States)

    Blecherman, S. S.

    1980-01-01

    A program was conducted to design, fabricate and test a durable, low cost, lightweight composite fan exit guide vane for high bypass ratio gas turbine engine application. Eight candidate material/design combinations were evaluated by NASTRAN finite element analysis. Four of these candidate systems were selected for composite vane fabrication by two vendors. A core and shell vane design was chosen in which the unidirectional graphite core fiber was the same for all candidates. The shell material, fiber orientation and ply configuration were varied. Material tests were performed on raw material and composite specimens to establish specification requirements. Composite vanes were nondestructively inspected and subsequently fatigue tested in both dry and 'wet' conditions. The program provided relevant data with respect to design analysis, materials properties, inspection standards, improved durability, weight benefits and part price of the composite fan exit guide vane.

  11. Surface Plasmon Wave Adapter Designed with Transformation Optics

    DEFF Research Database (Denmark)

    Zhang, Jingjing; Xiao, Sanshui; Wubs, Martijn

    2011-01-01

    On the basis of transformation optics, we propose the design of a surface plasmon wave adapter which confines surface plasmon waves on non-uniform metal surfaces and enables adiabatic mode transformation of surface plasmon polaritons with very short tapers. This adapter can be simply achieved...... with homogeneous anisotropic naturally occurring materials or subwavelength grating-structured dielectric materials. Full wave simulations based on a finite-element method have been performed to validate our proposal....

  12. Surface Plasmon Wave Adapter Designed with Transformation Optics

    DEFF Research Database (Denmark)

    Zhang, Jingjing; Xiao, Sanshui; Wubs, Martijn;

    2011-01-01

    On the basis of transformation optics, we propose the design of a surface plasmon wave adapter which confines surface plasmon waves on non-uniform metal surfaces and enables adiabatic mode transformation of surface plasmon polaritons with very short tapers. This adapter can be simply achieved...... with homogeneous anisotropic naturally occurring materials or subwavelength grating-structured dielectric materials. Full wave simulations based on a finite-element method have been performed to validate our proposal....

  13. Design of a surface alloy catalyst for steam reforming

    DEFF Research Database (Denmark)

    Besenbacher, F.; Chorkendorff, Ib; Clausen, B.S.;

    1998-01-01

    Detailed studies of elementary chemical processes on well-characterized single crystal surfaces have contributed substantially to the understanding of heterogeneous catalysis. insight into the structure of surface alloys combined with an understanding of the relation between the surface composition...... and reactivity is shown to lead directly to new ideas for catalyst design, The feasibility of such an approach is illustrated by the synthesis, characterization, and tests of a high-surface area gold-nickel catalyst for steam reforming....

  14. Technical Support Document: The Development of the Advanced Energy Design Guide for Small Retail Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Bing; Jarnagin, Ronald E.; Winiarski, David W.; Jiang, Wei; McBride, Merle F.; Crall, C.

    2006-09-30

    The Advanced Energy Design Guide for Small Retail Buildings (AEDG-SR) was developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA), the United States Green Buildings Council (USGBC), and the Department of Energy (DOE). The guide is intended to offer recommendations to achieve 30% energy savings and thus to encourage steady progress towards net-zero energy buildings. The baseline level energy use was set at buildings built at the turn of the millennium, which are assumed to be based on ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings (refer to as the ?Standard? in this report). ASHRAE and its partners are engaged in the development of a series of guides for small commercial buildings, with the AEDG-SR being the second in the series. Previously the partnership developed the Advanced Energy Design Guide for Small Office Buildings: Achieving 30% Energy Savings Over ANSI/ASHRAE/IESNA Standard 90.1-1999, which was published in late 2004. The technical support document prepared by PNNL details how the energy analysis performed in support of the Guide and documents development of recommendation criteria.

  15. Curiosity's Autonomous Surface Safing Behavior Design

    Science.gov (United States)

    Neilson, Tracy A.; Manning, Robert M.

    2013-01-01

    The safing routines on all robotic deep-space vehicles are designed to put the vehicle in a power and thermally safe configuration, enabling communication with the mission operators on Earth. Achieving this goal is made a little more difficult on Curiosity because the power requirements for the core avionics and the telecommunication equipment exceed the capability of the single power source, the Multi-Mission Radioisotope Thermoelectric Generator. This drove the system design to create an operational mode, called "sleep mode", where the vehicle turns off most of the loads in order to charge the two Li-ion batteries. The system must keep the vehicle safe from over-heat and under-heat conditions, battery cell failures, under-voltage conditions, and clock failures, both while the computer is running and while the system is sleeping. The other goal of a safing routine is to communicate. On most spacecraft, this simply involves turning on the receiver and transmitter continuously. For Curiosity, Earth is above the horizon only a part of the day for direct communication to the Earth, and the orbiter overpass opportunities only occur a few times a day. The design must robustly place the Rover in a communicable condition at the correct time. This paper discusses Curiosity's autonomous safing behavior and describes how the vehicle remains power and thermally safe while sleeping, as well as a description of how the Rover communicates with the orbiters and Earth at specific times.

  16. Linear programming and algorithms for communication networks a practical guide to network design, control, and management

    CERN Document Server

    Oki, Eiji

    2012-01-01

    Explaining how to apply to mathematical programming to network design and control, Linear Programming and Algorithms for Communication Networks: A Practical Guide to Network Design, Control, and Management fills the gap between mathematical programming theory and its implementation in communication networks. From the basics all the way through to more advanced concepts, its comprehensive coverage provides readers with a solid foundation in mathematical programming for communication networks. Addressing optimization problems for communication networks, including the shortest path problem, max f

  17. Electrostatic surface guiding of cold polar molecules with double charged wires

    Institute of Scientific and Technical Information of China (English)

    Yong Xia; Lianzhong Deng; Jinming Liu; Jianping Yin

    2005-01-01

    We propose a novel scheme to guide cold polar molecules on the surface of an insulating substrate (i.e., a chip) using a static electric field generated by the combination of a pair of parallel charged wires and a grounded metal plate. We calculate the spatial distributions of the electric fields from the above chargedwire layout and their Stark potentials for cold CO molecules, and analyze the relationships between the electric field and the parameters of the charged-wire layout. The result shows that this charged-wire scheme can be used to guide cold polar molecules in the weak-field-seeking state and to form various molecule-optical elements, even to realize a single-mode molecular waveguide on a molecule chip under certain conditions.

  18. Nonreciprocal propagation of surface plasmon mode guided through graphene layer on magnetized semiconductor

    Science.gov (United States)

    Bhagyaraj, C.; Mathew, Vincent

    2017-01-01

    This paper discusses the nonreciprocal effect induced by magnetized semiconductor substrate on surface plasmon mode guided through monolayer graphene. Dispersion relation for the fundamental antisymmetric mode is derived analytically. Nonreciprocal propagation characteristics of fundamental mode is studied as a function of wavelength, graphene layer chemical potential and biasing magnetic field. Fundamental mode exhibits appreciable nonreciprocal dispersion for transversal magnetization of semiconductor substrate in midinfrared and terahertz frequencies. Cutoff wavelength for backward propagating mode is observed above 2.5 T of external biasing field. Cutoff wavelength is found to be decreasing with increase in the biasing magnetic field and cladding index, also identified to be independent of graphene layer chemical potential. Proposed waveguide structure suggests the possibility of realizing one way propagating plasmonic waveguides with widely tunable guiding characteristics and related functional devices such as isolators, modulators, phase shifters and switches for integrated photonic circuits.

  19. User Experience Re-Mastered Your Guide to Getting the Right Design

    CERN Document Server

    Wilson, Chauncey

    2009-01-01

    Good user interface design isn’t just about aesthetics or using the latest technology. Designers also need to ensure their product is offering an optimal user experience. This requires user needs analysis, usability testing, persona creation, prototyping, design sketching, and evaluation through-out the design and development process. User Experience Re-Mastered takes tried and tested material from best-selling books in Morgan Kaufmann’s Series in Interactive Technologies and presents it in typical project framework. Chauncey Wilson guides the reader through each chapter, introducing each stag

  20. Pattern design on 3D triangular garment surfaces

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper focuses on a pattern design method for a 3D triangular garment surface. Firstly, some definitions of 3D style lines are proposed for designing the boundaries of patterns as drawing straight lines or splines on the triangular surface.Additionally some commonly used style lines are automatically generated to enhance design efficiency. Secondly, after style lines are preprocessed, a searching method is presented for quickly obtaining the boundaries and patches of a pattern on the 3D triangular surface. Finally a new pattern design reuse method is introduced by encoding/decoding the style line information. After style lines are encoded, the pattern design information can be saved in a pattern template and when decoding this template on a new garment surface, it automates the pattern generation for made-to-measure apparel products.

  1. Mixed-signal methodology guide advanced methodology for AMS IP and SOC design, verification and implementation

    CERN Document Server

    Chen, Jess; Mar, Monte F; Nizic, Mladen; Bailey, Brian

    2012-01-01

    This Book, The Mixed-Signal Methodology Guide: Advanced Methodology For Ams Ip And Soc Design, Verification, And Implementation Provides A Broad Overview Of The Design, Verification And Implementation Methodologies Required For Today's Mixed-Signal Designs. The Book Covers Mixed-Signal Design Trends And Challenges, Abstraction Of Analog Using Behavioral Models, Assertion-Based Metric-Driven Verification Methodology Applied On Analog And Mixed-Signal And Verification Of Low Power Intent In Mixed-Signal Design. It Also Describes Methodology For Physical Implementation In Context Of Concurrent Mixed-Signal Design And For Handling Advanced Node Physical Effects. The Book Contains Many Practical Examples Of Models And Techniques. The Authors Believe It Should Serve As A Reference To Many Analog, Digital And Mixed-Signal Designers, Verification, Physical Implementation Engineers And Managers In Their Pursuit Of Information For A Better Methodology Required To Address The Challenges Of Modern Mixed-Signal Design.

  2. Design of self-supporting surfaces

    KAUST Repository

    Vouga, Etienne

    2012-07-01

    Self-supporting masonry is one of the most ancient and elegant techniques for building curved shapes. Because of the very geometric nature of their failure, analyzing and modeling such strutures is more a geometry processing problem than one of classical continuum mechanics. This paper uses the thrust network method of analysis and presents an iterative nonlinear optimization algorithm for efficiently approximating freeform shapes by self-supporting ones. The rich geometry of thrust networks leads us to close connections between diverse topics in discrete differential geometry, such as a finite-element discretization of the Airy stress potential, perfect graph Laplacians, and computing admissible loads via curvatures of polyhedral surfaces. This geometric viewpoint allows us, in particular, to remesh self-supporting shapes by self-supporting quad meshes with planar faces, and leads to another application of the theory: steel/glass constructions with low moments in nodes. © 2012 ACM 0730-0301/2012/08-ART87.

  3. Study on design of the regular concave surface profiles

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Regular concave surface profiles are adopted in many friction surfaces. But up to now,this is seldom tutored by the theory of lubrication. To design them, a model of the regular depthoptimization was provided. To determine the other size, two propositions are given. At same time,two main effect factors on lubrication were discussed in detail. A lubrication test for different regu-lar concave surface profiles was performed on a pin and ring tester. On the basis of theory analy-sis and experiment, a principle to design regular concave surface profiles is provided.

  4. ASPHERICAL SURFACES APPROXIMATION IN AUTOMATED DESIGN OF OPTICAL SYSTEMS

    Directory of Open Access Journals (Sweden)

    T. V. Ivanova

    2015-07-01

    Full Text Available Subject of Research. The paper deals with the problems of higher order aspherical surfaces approximation using different equation types. The objects of research are two types of equations for higher order aspherical surfaces description used in different software for optical systems design (SАRО, OPAL, ZEMAX, CODE-V, etc. and dependent on z-coordinate or on a radial coordinate on the surface. Conversion from one type of equations to another is considered in view of application in different software for optical systems design. Methods. The subject matter of the method lies in usage of mean square method approximation for recalculation of high-order aspherical surface. Iterative algorithm for recalculation is presented giving the possibility to recalculate coefficients for different types of equations with required accuracy. Recommendations are given for choosing recalculation parameters such as the number of result equation coefficients, the number of points for recalculation and point allocation on a surface. Main Results. Example of recalculation for aspherical surface and accuracy estimation, including result aberration comparison between initial surface and recalculated surface are presented. The example has shown that required accuracy of surface representation was obtained. Practical Relevance. This technique is usable for recalculation of higher order aspherical surfaces in various types of software for optical systems design and also for research of optimal higher order aspherical surfaces description.

  5. Standardized surface engineering design of shale gas reservoirs

    Directory of Open Access Journals (Sweden)

    Guangchuan Liang

    2016-01-01

    Full Text Available Due to the special physical properties of shale gas reservoirs, it is necessary to adopt unconventional and standardized technologies for its surface engineering construction. In addition, the surface engineering design of shale gas reservoirs in China faces many difficulties, such as high uncertainty of the gathering and transportation scale, poor adaptability of pipe network and station layout, difficult matching of the process equipments, and boosting production at the late stage. In view of these problems, the surface engineering construction of shale gas reservoirs should follow the principles of “standardized design, modularized construction and skid mounted equipment”. In this paper, standardized surface engineering design technologies for shale gas reservoirs were developed with the “standardized well station layout, universal process, modular function zoning, skid mounted equipment selection, intensive site design, digitized production management” as the core, after literature analysis and technology exploration were carried out. Then its application background and surface technology route were discussed with a typical shale gas field in Sichuan–Chongqing area as an example. Its surface gathering system was designed in a standardized way, including standardized process, the modularized gathering and transportation station, serialized dehydration unit and intensive layout, and remarkable effects were achieved. A flexible, practical and reliable ground production system was built, and a series of standardized technology and modularized design were completed, including cluster well platform, set station, supporting projects. In this way, a system applicable to domestic shale gas surface engineering construction is developed.

  6. Guided wave propagation along the surface of a one-dimensional solid-fluid phononic crystal

    Science.gov (United States)

    Moiseyenko, Rayisa P.; Declercq, Nico F.; Laude, Vincent

    2013-09-01

    We consider an arbitrary periodic corrugated surface of a semi-infinite elastic solid that is immersed in a fluid, forming a one-dimensional phononic crystal. We study the existence and the polarization of guided waves that propagate along the interface. A coupled elastic-acoustic variational model is devised to obtain the dispersion of guided waves, which is implemented with a finite element method. It is found that the deeply corrugated interface supports a family of interface waves whose phase velocity decreases as the corrugation depth increases. Among these interface waves, some display an evanescent decay in the fluid that is reminiscent of the Scholte-Stoneley wave, while others propagate in the solid without causing significant pressure variation in the fluid, or cause localized pressure variations only inside the corrugation openings. The obtained results open the way for the study of conversions between bulk and surface waves in solid-fluid phononic crystals, and their use for wave confinement at the surface.

  7. Design and use of guided mode resonance filters for refractive index sensing

    DEFF Research Database (Denmark)

    Hermannsson, Pétur Gordon

    This Ph.D. thesis is concerned with the design and use of guided mode resonance filters (GMRF) for applications in refractive index sensing. GMRFs are optical nanostructures capable of efficiently and resonantly reflecting a narrow wavelength interval of incident broad band light. They combine...... a diffractive element with a waveguiding element, and it is the coupling between diffracted light and quasi guided modes that gives rise to the resonant response. The linewidth of the resonance can be tuned by the material and geometrical configuration of the device. The resonance wavelength is highly sensitive...... to changes in refractive index that occur within the region overlapped by the quasi guided mode, and GMRFs are thus well suited for optical sensing and tunable filter applications. They produce a polarization dependent response and can be optically characterized in both reflection and transmission...

  8. Achieving 50% Energy Savings in Office Buildings, Advanced Energy Design Guides: Office Buildings (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2014-09-01

    This fact sheet summarizes recommendations for designing new office buildings that result in 50% less energy use than conventional designs meeting minimum code requirements. The recommendations are drawn from the Advanced Energy Design Guide for Small to Medium Office Buildings, an ASHRAE publication that provides comprehensive recommendations for designing low-energy-use office buildings with gross floor areas up to 100,000 ft2 (see sidebar). Designed as a stand-alone document, this fact sheet provides key principles and a set of prescriptive design recommendations appropriate for smaller office buildings with insufficient budgets to fully implement best practices for integrated design and optimized performance. The recommendations have undergone a thorough analysis and review process through ASHRAE, and have been deemed the best combination of measures to achieve 50% savings in the greatest number of office buildings.

  9. Abnormal Cutoff Thickness of Long-Range Surface Plasmon Polariton Modes Guided by Thin Metal Films

    Institute of Scientific and Technical Information of China (English)

    LIU Fang; RAO Yi; HUANG Yi-Dong; ZHANG Wei; PENG Jiang-De

    2007-01-01

    Long-range surface plasmon polariton(LRSPP) modes guided by a thin metal film surrounded by semi-infinite dielectrics with different refractive indices are studied.Our cMculation results show that the cutoff thickness of the metal film does not monotonically increase with refractive index difference △n between the SHbstrate and superstrate.Just because of this abnormal behaviour of cutoff thickness,the existence of LRSPP illustrates complicated situations in asymmetric configurations.For a certain metal film thickness,LRsPP may exist in one.two or three refractive index difference △n regions.

  10. Phase effects in guided mode resonances II: measuring the angular phase of a surface plasmon polariton

    Science.gov (United States)

    Theisen, M. J.; Brown, T. G.

    2015-02-01

    We show how the phase of a resonant interaction between a focused beam and a guided mode can be directly observed in a pupil imaging experiment, in which the irradiance leaving the pupil of a standard microscope is relayed to an image sensor through a combination Wollaston prism, calcite beam splitter and polarizer. We apply the method to the observation of a surface plasmon polariton resonance excited in a corrugated silver film fabricated using electron beam lithography. We discuss how this particular imaging configuration could be adapted for applications in plasmonic optical sensing.

  11. Distillation Designs for the Lunar Surface

    Science.gov (United States)

    Boul, Peter J.; Lange,Kevin E.; Conger, Bruce; Anderson, Molly

    2010-01-01

    Gravity-based distillation methods may be applied to the purification of wastewater on the lunar base. These solutions to water processing are robust physical separation techniques, which may be more advantageous than many other techniques for their simplicity in design and operation. The two techniques can be used in conjunction with each other to obtain high purity water. The components and feed compositions for modeling waste water streams are presented in conjunction with the Aspen property system for traditional stage distillation. While the individual components for each of the waste streams will vary naturally within certain bounds, an analog model for waste water processing is suggested based on typical concentration ranges for these components. Target purity levels for recycled water are determined for each individual component based on NASA s required maximum contaminant levels for potable water Optimum parameters such as reflux ratio, feed stage location, and processing rates are determined with respect to the power consumption of the process. Multistage distillation is evaluated for components in wastewater to determine the minimum number of stages necessary for each of 65 components in humidity condensate and urine wastewater mixed streams.

  12. Accuracy of Three-Dimensional Printed Templates for Guided Implant Placement Based on Matching a Surface Scan with CBCT.

    Science.gov (United States)

    Kernen, Florian; Benic, Goran I; Payer, Michael; Schär, Alex; Müller-Gerbl, Magdalena; Filippi, Andreas; Kühl, Sebastian

    2016-08-01

    Reference elements are necessary to transfer a virtual planning into reality for guided implant placement. New systems allow matching optical scans with three-dimensional radiographic images. To test whether digitally designed three-dimensional printed templates (D-temp) fabricated by matching surface scans and cone beam computed tomography (CBCT) images differ from the templates fabricated in-lab (L-temp) by using a physical transfer device for the positioning of the guiding sleeves. L-temp were fabricated for eight human lower cadaver-jaws applying a digital planning software program (smop, Swissmeda AG, Zürich, Switzerland) using a Lego® (Lego Group, KIRKBI A/S, Billund, Denmark) brick as reference element and the respective transfer device (X1-table). Additionally, digital templates (D-temp) using the identical planning data sets and software were virtually designed and three-dimensional printed, after matching a surface scan with CBCT data. The accuracy of both templates for each planning was evaluated determining the estimated coronal, apical, and angular deviation if templates were used for implant placement. Mean coronal deviations for L-temp were 0.31 mm (mesial/distal), 0.32 mm (lingual/buccal), and 0.16 mm and 0.23 mm for D-temp, respectively. The mean apical deviations for L-temp were 0.50 mm (mesial/distal), 0.50 mm (lingual/buccal). and 0.25 mm and 0.34 mm for the D-temp, respectively. Differences between both devices were statistically significant (p virtual planning into reality. © 2015 Wiley Periodicals, Inc.

  13. Nanoscale guiding for cold atoms based on surface plasmons along the tips of metallic wedges

    Institute of Scientific and Technical Information of China (English)

    Wang Zheng-Ling; Tang Wei-Min; Zhou Ming; Gao Chuan-Yu

    2013-01-01

    We propose a novel scheme to guide neutral cold atoms in a nanoscale region based on surface plasmons (SPs) of one pair and two pairs of tips of metallic wedges with locally enhanced light intensity and sub-optical wavelength resolution.We analyze the near-field intensity distribution of the tip of the metallic wedge by the FDTD method,and study the total intensity as well as the total potential of optical potentials and van der Waals potentials for 87Rb atoms in the light field of one pair and two pairs of tips of metallic wedges.It shows that the total potentials of one pair and two pairs of tips of metallic wedges can generate a gravito-optical trap and a dark closed trap for nanoscale guiding of neutral cold atoms.Guided atoms can be cooled with efficient intensity-gradient Sisyphus cooling by blue-detuned light field.This provides an important step towards the generation of hybrid systems consisting of isolated atoms and solid devices.

  14. Making Sense of Data III A Practical Guide to Designing Interactive Data Visualizations

    CERN Document Server

    Myatt, Glenn J

    2011-01-01

    Focuses on insights, approaches, and techniques that are essential to designing interactive graphics and visualizations Making Sense of Data III: A Practical Guide to Designing Interactive Data Visualizations explores a diverse range of disciplines to explain how meaning from graphical representations is extracted. Additionally, the book describes the best approach for designing and implementing interactive graphics and visualizations that play a central role in data exploration and decision-support systems. Beginning with an introduction to visual perception, Making Sense of Data III featur

  15. A beginner's guide to 3D printing 14 simple toy designs to get you started

    CERN Document Server

    Rigsby, Mike

    2014-01-01

    A Beginner''s Guide to 3D Printing is the perfect resource for those who would like to experiment with 3D design and manufacturing, but have little or no technical experience with the standard software. Author Mike Rigsby leads readers step-by-step through 15 simple toy projects, each illustrated with screen caps of Autodesk 123D Design, the most common free 3D software available. The projects are later described using Sketchup, another free popular software package. Beginning with basics projects that will take longer to print than design, readers are then given instruction on more advanced t

  16. Classifier-guided sampling for discrete variable, discontinuous design space exploration: Convergence and computational performance

    Energy Technology Data Exchange (ETDEWEB)

    Backlund, Peter B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shahan, David W. [HRL Labs., LLC, Malibu, CA (United States); Seepersad, Carolyn Conner [Univ. of Texas, Austin, TX (United States)

    2014-04-22

    A classifier-guided sampling (CGS) method is introduced for solving engineering design optimization problems with discrete and/or continuous variables and continuous and/or discontinuous responses. The method merges concepts from metamodel-guided sampling and population-based optimization algorithms. The CGS method uses a Bayesian network classifier for predicting the performance of new designs based on a set of known observations or training points. Unlike most metamodeling techniques, however, the classifier assigns a categorical class label to a new design, rather than predicting the resulting response in continuous space, and thereby accommodates nondifferentiable and discontinuous functions of discrete or categorical variables. The CGS method uses these classifiers to guide a population-based sampling process towards combinations of discrete and/or continuous variable values with a high probability of yielding preferred performance. Accordingly, the CGS method is appropriate for discrete/discontinuous design problems that are ill-suited for conventional metamodeling techniques and too computationally expensive to be solved by population-based algorithms alone. In addition, the rates of convergence and computational properties of the CGS method are investigated when applied to a set of discrete variable optimization problems. Results show that the CGS method significantly improves the rate of convergence towards known global optima, on average, when compared to genetic algorithms.

  17. Achieving 50% Energy Savings in New Schools, Advanced Energy Design Guides: K-12 Schools (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2014-09-01

    This fact sheet summarizes recommendations for designing elementary, middle, and high school buildings that will result in 50% less energy use than conventional new schools built to minimum code requirements. The recommendations are drawn from the Advanced Energy Design Guide for K-12 School Buildings, an ASHRAE publication that provides comprehensive recommendations for designing low-energy-use school buildings (see sidebar). Designed as a stand-alone document, this fact sheet provides key principles and a set of prescriptive design recommendations appropriate for smaller schools with insufficient budgets to fully implement best practices for integrated design and optimized performance. The recommendations have undergone a thorough analysis and review process through ASHRAE, and have been deemed the best combination of measures to achieve 50% savings in the greatest number of schools.

  18. Technical Support Document: Development of the Advanced Energy Design Guide for Small Office Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Jarnagin, Ronald E.; Liu, Bing; Winiarski, David W.; McBride, Merle F.; Suharli, L.; Walden, D.

    2006-11-30

    This Technical Support Document (TSD) describes the process and methodology for the development of the Advanced Energy Design Guide for Small Office Buildings (AEDG-SO), a design guidance document intended to provide recommendations for achieving 30% energy savings in small office buildings over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The AEDG-SO is the first in a series of guides being developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc. (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA), the New Buildings Institute (NBI), and the U.S. Department of Energy (DOE). Each of the guides in the AEDG series will provide recommendations and user-friendly design assistance to designers, developers and owners of small commercial buildings that will encourage steady progress towards net-zero energy buildings. The guides will provide prescriptive recommendation packages that are capable of reaching the energy savings target for each climate zone in order to ease the burden of the design and construction of energy-efficient small commercial buildings The AEDG-SO was developed by an ASHRAE Special Project committee (SP-102) made up of representatives of each of the partner organizations in eight months. This TSD describes the charge given to the committee in developing the office guide and outlines the schedule of the development effort. The project committee developed two prototype office buildings (5,000 ft2 frame building and 20,000 ft2 two-story mass building) to represent the class of small office buildings and performed an energy simulation scoping study to determine the preliminary levels of efficiency necessary to meet the energy savings target. The simulation approach used by the project committee is documented in this TSD along with

  19. Integrating Surface Modeling into the Engineering Design Graphics Curriculum

    Science.gov (United States)

    Hartman, Nathan W.

    2006-01-01

    It has been suggested there is a knowledge base that surrounds the use of 3D modeling within the engineering design process and correspondingly within engineering design graphics education. While solid modeling receives a great deal of attention and discussion relative to curriculum efforts, and rightly so, surface modeling is an equally viable 3D…

  20. Integrating Surface Modeling into the Engineering Design Graphics Curriculum

    Science.gov (United States)

    Hartman, Nathan W.

    2006-01-01

    It has been suggested there is a knowledge base that surrounds the use of 3D modeling within the engineering design process and correspondingly within engineering design graphics education. While solid modeling receives a great deal of attention and discussion relative to curriculum efforts, and rightly so, surface modeling is an equally viable 3D…

  1. Design methodology to enhance high impedance surfaces performances

    Directory of Open Access Journals (Sweden)

    M. Grelier

    2014-04-01

    Full Text Available A methodology is introduced for designing wideband, compact and ultra-thin high impedance surfaces (HIS. A parametric study is carried out to examine the effect of the periodicity on the electromagnetic properties of an HIS. This approach allows designers to reach the best trade-off for HIS performances.

  2. Control System Design for a Surface Cleaning Robot

    Directory of Open Access Journals (Sweden)

    Zhai Yuyi

    2013-05-01

    Full Text Available This paper aims to study a control system for a surface cleaning robot and the focus of the study is the surface cleaning robot controller design. The structural framework of the propulsion control system of the surface robot is designed based on the principle of PWM speed control. The function of each module in the control system is divided and described in detail. A kind of thinking based on an AVR microprocessor and its software and hardware design proposals are presented. Through RS485 and PC communication according to the agreed protocol, the control system achieves robot forward, backward, turn and work operations by the use of a DC motor or stepper motor, and it can therefore more successfully realize the work of a surface cleaning robot.

  3. Information structure design for databases a practical guide to data modelling

    CERN Document Server

    Mortimer, Andrew J

    2014-01-01

    Computer Weekly Professional Series: Information Structure Design for Databases: A Practical Guide to Data modeling focuses on practical data modeling covering business and information systems. The publication first offers information on data and information, business analysis, and entity relationship model basics. Discussions cover degree of relationship symbols, relationship rules, membership markers, types of information systems, data driven systems, cost and value of information, importance of data modeling, and quality of information. The book then takes a look at entity relationship mode

  4. Novel Modeling Framework To Guide Design of Optimal Dosing Strategies for β-Lactamase Inhibitors

    OpenAIRE

    Bhagunde, Pratik; Chang, Kai-Tai; Hirsch, Elizabeth B.; Ledesma, Kimberly R.; Nikolaou, Michael; Tam, Vincent H.

    2012-01-01

    The scarcity of new antibiotics against drug-resistant bacteria has led to the development of inhibitors targeting specific resistance mechanisms, which aim to restore the effectiveness of existing agents. However, there are few guidelines for the optimal dosing of inhibitors. Extending the utility of mathematical modeling, which has been used as a decision support tool for antibiotic dosing regimen design, we developed a novel mathematical modeling framework to guide optimal dosing strategie...

  5. The Design of Food Storage Guided Vehicle System Based on RFID Technology

    Directory of Open Access Journals (Sweden)

    Rui Xue

    2015-08-01

    Full Text Available According to the characteristics of the food transport system, RFID technology is integrated in the AGV automatic guided vehicle system in the food warehousing. The node RFID oriented method is chosen and the RFID note positioning function is used to realize more types and over horizon identification loading, handling and automatic storage function that improves the system flexibility through the design of tag oriented system.

  6. Designing with the mind in mind simple guide to understanding user interface design guidelines

    CERN Document Server

    Johnson, Jeff

    2014-01-01

    In this completely updated and revised edition of Designing with the Mind in Mind, Jeff Johnson provides you with just enough background in perceptual and cognitive psychology that user interface (UI) design guidelines make intuitive sense rather than being just a list or rules to follow. Early UI practitioners were trained in cognitive psychology, and developed UI design rules based on it. But as the field has evolved since the first edition of this book, designers enter the field from many disciplines. Practitioners today have enough experience in UI design that they have been exposed to

  7. Fostering Autonomy Through Syllabus Design: A Step-by-Step Guide for Success

    Directory of Open Access Journals (Sweden)

    Alexánder Ramírez Espinosa

    2015-10-01

    Full Text Available Promoting learner autonomy is relevant in the field of applied linguistics due to the multiple benefits it brings to the process of learning a new language. However, despite the vast array of research on how to foster autonomy in the language classroom, it is difficult to find step-by-step processes to design syllabi and curricula focused on the development of learner autonomy. This paper presents a model of a successful English course, implemented at Universidad del Valle (Colombia, which is expected to serve as a practical guide to articulate the stages of design, implementation, and evaluation of an autonomy-fostering syllabus.

  8. Nanomaterial surface chemistry design for advancements in capillary electrophoresis modes.

    Science.gov (United States)

    Ivanov, Michael R; Haes, Amanda J

    2011-01-07

    Tailored surface chemistry impacts nanomaterial function and stability in applications including in various capillary electrophoresis (CE) modes. Although colloidal nanoparticles were first integrated as colouring agents in artwork and pottery over 2000 years ago, recent developments in nanoparticle synthesis and surface modification increased their usefulness and incorporation in separation science. For instance, precise control of surface chemistry is critically important in modulating nanoparticle functionality and stability in dynamic environments. Herein, recent developments in nanomaterial pseudostationary and stationary phases will be summarized. First, nanomaterial core and surface chemistry compositions will be classified. Next, characterization methods will be described and related to nanomaterial function in various CE modes. Third, methods and implications of nanomaterial incorporation into CE will be discussed. Finally, nanoparticle-specific mechanisms likely involved in CE will be related to nanomaterial surface chemistry. Better understanding of surface chemistry will improve nanoparticle design for the integration into separation techniques.

  9. Breaking-Cas-interactive design of guide RNAs for CRISPR-Cas experiments for ENSEMBL genomes.

    Science.gov (United States)

    Oliveros, Juan C; Franch, Mònica; Tabas-Madrid, Daniel; San-León, David; Montoliu, Lluis; Cubas, Pilar; Pazos, Florencio

    2016-07-08

    The CRISPR/Cas technology is enabling targeted genome editing in multiple organisms with unprecedented accuracy and specificity by using RNA-guided nucleases. A critical point when planning a CRISPR/Cas experiment is the design of the guide RNA (gRNA), which directs the nuclease and associated machinery to the desired genomic location. This gRNA has to fulfil the requirements of the nuclease and lack homology with other genome sites that could lead to off-target effects. Here we introduce the Breaking-Cas system for the design of gRNAs for CRISPR/Cas experiments, including those based in the Cas9 nuclease as well as others recently introduced. The server has unique features not available in other tools, including the possibility of using all eukaryotic genomes available in ENSEMBL (currently around 700), placing variable PAM sequences at 5' or 3' and setting the guide RNA length and the scores per nucleotides. It can be freely accessed at: http://bioinfogp.cnb.csic.es/tools/breakingcas, and the code is available upon request.

  10. VERSE-Guided Numerical RF Pulse Design: A Fast Method for Peak RF Power Control

    Science.gov (United States)

    Lee, Daeho; Grissom, William A.; Lustig, Michael; Kerr, Adam B.; Stang, Pascal P.; Pauly, John M.

    2013-01-01

    In parallel excitation, the computational speed of numerical radiofrequency (RF) pulse design methods is critical when subject dependencies and system nonidealities need to be incorporated on-the-fly. One important concern with optimization-based methods is high peak RF power exceeding hardware or safety limits. Hence, online controllability of the peak RF power is essential. Variable-rate selective excitation pulse reshaping is ideally suited to this problem due to its simplicity and low computational cost. In this work, we first improve the fidelity of variable-rate selective excitation implementation for discrete-time waveforms through waveform oversampling such that variable-rate selective excitation can be robustly applied to numerically designed RF pulses. Then, a variable-rate selective excitation-guided numerical RF pulse design is suggested as an online RF pulse design framework, aiming to simultaneously control peak RF power and compensate for off-resonance. PMID:22135085

  11. Inverse design of nanostructured surfaces for color effects

    DEFF Research Database (Denmark)

    Andkjær, Jacob Anders; Johansen, Villads Egede; Friis, Kasper Storgaard;

    2014-01-01

    We propose an inverse design methodology for systematic design of nanostructured surfaces for color effects. The methodology is based on a 2D topology optimization formulation based on frequency-domain finite element simulations for E and/or H polarized waves. The goal of the optimization...... is to maximize color intensity in prescribed direction(s) for a prescribed color (RGB) vector. Results indicate that nanostructured surfaces with any desirable color vector can be generated; that complex structures can generate more intense colors than simple layerings; that angle independent colorings can...

  12. Designing with the mind in mind simple guide to understanding user interface design rules

    CERN Document Server

    Johnson, Jeff

    2010-01-01

    "Take fundamental principles of psychology. Illustrate. Combine with Fundamental Principles of Design. Stir gently until fully blended.  Read daily until finished. Caution: The mixture is addictive."-- Don Norman, Nielsen Norman group, Author of Design of Future Things."This book is a primer to understand the why of the larger human action principles at work-a sort of cognitive science for designers in a hurry. Above all, this is a book of profound insight into the human mind for practical people who want to get something done."-- Stuart Card, Senior Research Fellow and the manager of the

  13. Sikorsky interactive graphics surface design/manufacturing system

    Science.gov (United States)

    Robbins, R.

    1975-01-01

    An interactive graphics system conceived to be used in the design, analysis, and manufacturing of aircraft components with free form surfaces was described. In addition to the basic surface definition and viewing capabilities inherent in such a system, numerous other features are present: surface editing, automated smoothing of control curves, variable milling patch boundary definitions, surface intersection definition and viewing, automatic creation of true offset surfaces, digitizer and drafting machine interfaces, and cutter path optimization. Documented costs and time savings of better than six to one are being realized with this system. The system was written in FORTRAN and GSP for use on IBM 2250 CRT's in conjunction with an IBM 370/158 computer.

  14. Optimum Design Of Addendum Surfaces In Sheet Metal Forming Process

    Science.gov (United States)

    Debray, K.; Sun, Z. C.; Radjai, R.; Guo, Y. Q.; Dai, L.; Gu, Y. X.

    2004-06-01

    The design of addendum surfaces in sheet forming process is very important for the product quality, but it is very time-consuming and needs tedious trial-error corrections. In this paper, we propose a methodology to automatically generate the addendum surfaces and then to optimize them using a forming modelling solver. The surfaces' parameters are taken as design variables and modified in course of optimization. The finite element mesh is created on the initial addendum surfaces and mapped onto the modified surfaces without remeshing operation. The Feasible Sequential Quadratic Programming (FSQP) is adopted as our algorithm of optimization. Two objective functions are used: the first one is the thickness function to minimize the thickness variation on the workpiece ; the second one is the appearance function aiming to avoid the scratching defects on the external surfaces of panels. The FSQP is combined with our "Inverse Approach" or "One Step Approach" which is a very fast forming solver. This leads to a very efficient optimization procedure. The present methodology is applied to a square box. The addendum surfaces are characterised by four geometrical variables. The influence of optimization criteria is studied and discussed.

  15. Surface-based registration accuracy of CT-based image-guided spine surgery.

    Science.gov (United States)

    Tamura, Yuichi; Sugano, Nobuhiko; Sasama, Toshihiko; Sato, Yoshinobu; Tamura, Shinichi; Yonenobu, Kazuo; Yoshikawa, Hideki; Ochi, Takahiro

    2005-04-01

    Registration is a critical and important process in maintaining the accuracy of CT-based image-guided surgery. The aim of this study was to evaluate the effects of the area of intraoperative data sampling and number of sampling points on the accuracy of surface-based registration in a CT-based spinal-navigation system, using an optical three-dimensional localizer. A cadaveric dry-bone phantom of the lumbar spine was used. To evaluate registration accuracy, three alumina ceramic balls were attached to the anterior and lateral aspects of the vertebral body. CT images of the phantom were obtained (1-mm slice thickness, at1-mm intervals) using a helical CT scanner. Twenty surface points were digitized from five zones defined on the basis of anatomical classification on the posterior aspects of the target vertebra. A total of 20 sets of sampling data were obtained. Evaluation of registration accuracy accounted for positional and rotational errors. Of the five zones, the area that was the largest and easiest to expose surgically and to digitize surface points was the lamina. The lamina was defined as standard zone. On this zone, the effect of the number of sampling points on the positional and rotational accuracy of registration was evaluated. And the effects of the additional area selected for intraoperative data sampling on the registration accuracy were evaluated. Using 20 surface points on the posterior side of the lamina, positional error was 0.96 mm +/- 0.24 mm root-mean-square (RMS) and rotational error was 0.91 degrees +/- 0.38 degrees RMS. The use of 20 surface points on the lamina usually allows surgeons to carry out sufficiently accurate registration to conduct computer-aided spine surgery. In the case of severe spondylosis, however, it might be difficult to digitize the surface points from the lamina, due to a hypertrophic facet joint or the deformity of the lamina and noisy sampling data. In such cases, registration accuracy can be improved by combining use

  16. Solar heat. Guide for design and construction of systems. Solvarme. Vejledning i projektering og udfoerelse af anlaeg

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    The purpose of this Guide (second revised edition) is: 1) to give a review of use and design of solar heating systems, 2) to evaluate the consequences of solar heating for building, constructional, siting and architectual relationships, 3) to evaluate the prospects of solar heating in a particular project. The Guide is mainly based on heating systems with flat solar collectors and liquid heat medium designed to heat space or water in smaller houses. Static calculations, architectural standards and economic aspects are reviewed.

  17. A new method for designing a developable surface utilizing the surface pencil through a given curve

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This paper proposes a new method for designing a developable surface by constructing a surface pencil passing through a given curve,which is quite in accord with the practice in industry design and manufacture. By utilizing the Frenet trihedron frame, we derive the necessary and sufficient conditions to construct a developable surface through a given curve. Considering the requirements in shoemaking and garment-manufacture industries, we also study the special case of specifying the given curve as a geodesic. The given geodesic can be classified into three types corresponding to each type of developable surface. We also present the polynomial representation of the developable surface. The algorithm is convenient and efficient for applications in engineering.

  18. Circuit Design of Surface Acoustic Wave Based Micro Force Sensor

    Directory of Open Access Journals (Sweden)

    Yuanyuan Li

    2014-01-01

    Full Text Available Pressure sensors are commonly used in industrial production and mechanical system. However, resistance strain, piezoresistive sensor, and ceramic capacitive pressure sensors possess limitations, especially in micro force measurement. A surface acoustic wave (SAW based micro force sensor is designed in this paper, which is based on the theories of wavelet transform, SAW detection, and pierce oscillator circuits. Using lithium niobate as the basal material, a mathematical model is established to analyze the frequency, and a peripheral circuit is designed to measure the micro force. The SAW based micro force sensor is tested to show the reasonable design of detection circuit and the stability of frequency and amplitude.

  19. Static characteristics design of hydrostatic guide-ways based on fluid-structure interactions

    Science.gov (United States)

    Lin, Shuo; Yin, YueHong

    2016-10-01

    With the raising requirements in micro optical systems, the available machines become hard to achieve the process dynamic and accuracy in all aspects. This makes compact design based on fluid/structure interactions (FSI) important. However, there is a difficulty in studying FSI with oil film as fluid domain. This paper aims at static characteristic design of a hydrostatic guide-way with capillary restrictors based on FSI. The pressure distribution of the oil film land is calculated by solving the Reynolds-equation with Galerkin technique. The deformation of structure is calculated by commercial FEM software, MSC. Nastran. A matlab program is designed to realize the coupling progress by modifying the load boundary in the submitting file and reading the deformation result. It's obvious that the stiffness of the hydrostatic bearing decreases with the weakening of the bearing structure. This program is proposed to make more precise prediction of bearing stiffness.

  20. Towards Clinically Optimized MRI-guided Surgical Manipulator for Minimally Invasive Prostate Percutaneous Interventions: Constructive Design.

    Science.gov (United States)

    Eslami, Sohrab; Fischer, Gregory S; Song, Sang-Eun; Tokuda, Junichi; Hata, Nobuhiko; Tempany, Clare M; Iordachita, Iulian

    2013-12-31

    This paper undertakes the modular design and development of a minimally invasive surgical manipulator for MRI-guided transperineal prostate interventions. Severe constraints for the MRI-compatibility to hold the minimum artifact on the image quality and dimensions restraint of the bore scanner shadow the design procedure. Regarding the constructive design, the manipulator kinematics has been optimized and the effective analytical needle workspace is developed and followed by proposing the workflow for the manual needle insertion. A study of the finite element analysis is established and utilized to improve the mechanism weaknesses under some inevitable external forces to ensure the minimum structure deformation. The procedure for attaching a sterile plastic drape on the robot manipulator is discussed. The introduced robotic manipulator herein is aimed for the clinically prostate biopsy and brachytherapy applications.

  1. Towards Clinically Optimized MRI-guided Surgical Manipulator for Minimally Invasive Prostate Percutaneous Interventions: Constructive Design*

    Science.gov (United States)

    Eslami, Sohrab; Fischer, Gregory S.; Song, Sang-Eun; Tokuda, Junichi; Hata, Nobuhiko; Tempany, Clare M.; Iordachita, Iulian

    2013-01-01

    This paper undertakes the modular design and development of a minimally invasive surgical manipulator for MRI-guided transperineal prostate interventions. Severe constraints for the MRI-compatibility to hold the minimum artifact on the image quality and dimensions restraint of the bore scanner shadow the design procedure. Regarding the constructive design, the manipulator kinematics has been optimized and the effective analytical needle workspace is developed and followed by proposing the workflow for the manual needle insertion. A study of the finite element analysis is established and utilized to improve the mechanism weaknesses under some inevitable external forces to ensure the minimum structure deformation. The procedure for attaching a sterile plastic drape on the robot manipulator is discussed. The introduced robotic manipulator herein is aimed for the clinically prostate biopsy and brachytherapy applications. PMID:24683502

  2. Automated Control Surface Design and Sizing for the Prandtl Plane

    NARCIS (Netherlands)

    Van Ginneken, D.A.J.; Voskuijl, M.; Van Tooren, M.J.L.; Frediani, A.

    2010-01-01

    This paper presents a methodology for the design of the primary flight control surfaces, in terms of size, number and location, for fixed wing aircraft (conventional or unconventional). As test case, the methodology is applied to a 300 passenger variant of the Prandtl Plane. This box wing aircraft i

  3. Technical Practices Manual for Surface Ship Stack Design

    Science.gov (United States)

    1976-07-01

    publico releas5, Diitribution unlimted. n /___ 1J TECHNICAL PRACTICES MANUAL FOR SURFACE SIP STACK DESIGN, AVSECj R%~m,r 6136- 7-1 i /-Jul 76~\\ / Prepared...British Transport Commission for making deck, but so slowly that they can be regarded as virtually in available a cross-channel ship (ship A) on which the

  4. Design of structurally colored surfaces based on scalar diffraction theory

    DEFF Research Database (Denmark)

    Johansen, Villads Egede; Andkjær, Jacob Anders; Sigmund, Ole

    2014-01-01

    reflective surface, paint-free text and coloration, UV-resistant coloring, etc. In this initial study, the main focus is on finding a systematic way to obtain these results. For now the simulation and optimization is based on a simple scalar diffraction theory model. From the results, several design issues...

  5. Functional surfaces for tribological applications: inspiration and design

    Science.gov (United States)

    Abdel-Aal, Hisham A.

    2016-12-01

    Surface texturing has been recognized as a method for enhancing the tribological properties of surfaces for many years. Adding a controlled texture to one of two faces in relative motion can have many positive effects, such as reduction of friction and wear and increase in load capacity. To date, the true potential of texturing has not been realized not because of the lack of enabling texturing technologies but because of the severe lack of detailed information about the mechanistic functional details of texturing in a tribological situation. Experimental as well as theoretical analysis of textured surfaces define important metrics for performance evaluation. These metrics represent the interaction between geometry of the texturing element and surface topology. To date, there is no agreement on the optimal values that should be implemented given a particular surface. More importantly, a well-defined methodology for the generation of deterministic textures of optimized designs virtually does not exist. Nature, on the other hand, offers many examples of efficient texturing strategies (geometries and topologies) specifically applied to mitigate frictional effects in a variety of situations. Studying these examples may advance the technology of surface engineering. This paper therefore, provides a comparative review of surface texturing that manifest viable synergy between tribology and biology. We attempt to provide successful emerging examples where borrowing from nature has inspired viable surface solutions that address difficult tribological problems both in dry and lubricated contact situations.

  6. An ontology design pattern for surface water features

    Science.gov (United States)

    Sinha, Gaurav; Mark, David; Kolas, Dave; Varanka, Dalia; Romero, Boleslo E.; Feng, Chen-Chieh; Usery, E. Lynn; Liebermann, Joshua; Sorokine, Alexandre

    2014-01-01

    Surface water is a primary concept of human experience but concepts are captured in cultures and languages in many different ways. Still, many commonalities exist due to the physical basis of many of the properties and categories. An abstract ontology of surface water features based only on those physical properties of landscape features has the best potential for serving as a foundational domain ontology for other more context-dependent ontologies. The Surface Water ontology design pattern was developed both for domain knowledge distillation and to serve as a conceptual building-block for more complex or specialized surface water ontologies. A fundamental distinction is made in this ontology between landscape features that act as containers (e.g., stream channels, basins) and the bodies of water (e.g., rivers, lakes) that occupy those containers. Concave (container) landforms semantics are specified in a Dry module and the semantics of contained bodies of water in a Wet module. The pattern is implemented in OWL, but Description Logic axioms and a detailed explanation is provided in this paper. The OWL ontology will be an important contribution to Semantic Web vocabulary for annotating surface water feature datasets. Also provided is a discussion of why there is a need to complement the pattern with other ontologies, especially the previously developed Surface Network pattern. Finally, the practical value of the pattern in semantic querying of surface water datasets is illustrated through an annotated geospatial dataset and sample queries using the classes of the Surface Water pattern.

  7. EuPaGDT: a web tool tailored to design CRISPR guide RNAs for eukaryotic pathogens.

    Science.gov (United States)

    Peng, Duo; Tarleton, Rick

    2015-10-01

    Recent development of CRISPR-Cas9 genome editing has enabled highly efficient and versatile manipulation of a variety of organisms and adaptation of the CRISPR-Cas9 system to eukaryotic pathogens has opened new avenues for studying these otherwise hard to manipulate organisms. Here we describe a webtool, Eukaryotic Pathogen gRNA Design Tool (EuPaGDT; available at http://grna.ctegd.uga.edu), which identifies guide RNA (gRNA) in input gene(s) to guide users in arriving at well-informed and appropriate gRNA design for many eukaryotic pathogens. Flexibility in gRNA design, accommodating unique eukaryotic pathogen (gene and genome) attributes and high-throughput gRNA design are the main features that distinguish EuPaGDT from other gRNA design tools. In addition to employing an array of known principles to score and rank gRNAs, EuPaGDT implements an effective on-target search algorithm to identify gRNA targeting multi-gene families, which are highly represented in these pathogens and play important roles in host-pathogen interactions. EuPaGDT also identifies and scores microhomology sequences flanking each gRNA targeted cut-site; these sites are often essential for the microhomology-mediated end joining process used for double-stranded break repair in these organisms. EuPaGDT also assists users in designing single-stranded oligonucleotides for homology directed repair. In batch processing mode, EuPaGDT is able to process genome-scale sequences, enabling preparation of gRNA libraries for large-scale screening projects.

  8. Colloid and surface chemistry a laboratory guide for exploration of the nano world

    CERN Document Server

    Bucak, Seyda

    2013-01-01

    Scientific Research The research processEthics in Science Design of Experiments Fundamentals of Scientific Computing, Nihat Baysal Recording Data: Keeping a Good Notebook Presenting Data: Writing a Laboratory ReportReferencesCharacterization Techniques Surface Tension Measurements, Seyda BucakViscosity/Rheological Measurements, Patrick UnderhillElectrokinetic Techniques, Marek KosmulskiDiffraction (XRD), Deniz RendeScattering, Ulf OlssonMicroscopy, Cem Levent Altan and Nico A.J.M. SommerdijkColloids and Surfaces Experiment 1: SedimentationExperiment 2: Determination of Critical Micelle Concent

  9. Design, fabrication, integration and commissioning of an upgraded guiding probe for the VLT unit telescope 4

    Science.gov (United States)

    Frank, Christoph; Hammersley, Peter; Buzzoni, Bernard; Manescau, Antonio; Arsenault, Robin; Madec, Pierre-Yves; Birkmann, Martin; Mueller, Michael; Salgado, Fernando; Guisard, Stephane; Kroedel, Matthias

    2014-07-01

    As part of the preparation for the arrival of the MUSE instrument to the VLT, it was required to adapt the hosting telescope (UT4) guide probe, to increase its back focal length. This is to allow enough space for the later deployment of the MUSE Adaptive Optics module GALACSI, in-between the telescope adapter rotator and the instrument itself. The UT guide probe is a critical component for the successful operation of the telescope, so its modification to increase the telescope's back focal length, while maintaining full compatibility with the existing operation model and other hardware, was rather demanding. The design, manufacture, assembly and test for the new supporting arm in the UT guiding probe is presented. It mixes the use of novel materials (HB-CESIC® for the mirrors substrates) and state of the art manufacturing techniques (3D printing mould production and rapid casting for the support structure), which allow producing easily a high performance subsystem. Characterization of the system prior delivery to the telescope, its integration in the UT and results after commissioning is presented. Its successful implementation has validated new manufacturing techniques that may prove very useful for future instruments development.

  10. Microfabricated surface designs for cell culture and diagnosis.

    Science.gov (United States)

    Matsuda, T; Chung, D J

    1994-01-01

    Grooved and holed surfaces with a well fabricated design may serve as microsubstrates for cell culture and microreactors for diagnosis. In this study, the authors prepared chemically treated, micrometer scale grooved and holed glass surfaces by combined surface modification and ultraviolet (UV) excimer laser ablation techniques, as follows. 1) Microcell-culture substrate: Amino group attached glass surfaces, prepared by the treatment with an aminopropylsilane, were condensed with a carboxylated radical initiator. Subsequently, polyacrylamide was grafted by surface initiated radical polymerization to create a very hydrophilic surface layer. Ultraviolet excimer laser beams (KrF: 248 nm) were irradiated through a microscope onto surfaces to create grooves or holes that were 10 and 50 microns in width or diameter, respectively. The depth, depending on the irradiation light strength, ranged from a few to several tenths of a micrometer. On endothelial cell (EC) seeding, ECs adhered and grew on the bottoms of the grooved or holed surface where glass was exposed on ablation. Little cell adhesion was observed on non ablated, grafted surfaces. Endothelial cells aligned along the groove, resulting in very narrow tube like tissue formation, whereas ECs tended to form a multilayered spherical aggregate in a hole. A single cell resided in a 10 microns square hole. 2) Microreactor for diagnosis: The glass surface, treated with a fluorinated silane, was ablated to create round holes. On addition of a few microliters of water, water could be quantitatively transferred into a hole because of the water repellent characteristics of non ablated, fluorinated glass. As a model of a microreactor, enzyme reactions to affect different levels of glucose were carried out in tiny holed surfaces.

  11. Design Application Translates 2-D Graphics to 3-D Surfaces

    Science.gov (United States)

    2007-01-01

    Fabric Images Inc., specializing in the printing and manufacturing of fabric tension architecture for the retail, museum, and exhibit/tradeshow communities, designed software to translate 2-D graphics for 3-D surfaces prior to print production. Fabric Images' fabric-flattening design process models a 3-D surface based on computer-aided design (CAD) specifications. The surface geometry of the model is used to form a 2-D template, similar to a flattening process developed by NASA's Glenn Research Center. This template or pattern is then applied in the development of a 2-D graphic layout. Benefits of this process include 11.5 percent time savings per project, less material wasted, and the ability to improve upon graphic techniques and offer new design services. Partners include Exhibitgroup/Giltspur (end-user client: TAC Air, a division of Truman Arnold Companies Inc.), Jack Morton Worldwide (end-user client: Nickelodeon), as well as 3D Exhibits Inc., and MG Design Associates Corp.

  12. Crystal-Structure-Guided Design of Self-Assembling RNA Nanotriangles.

    Science.gov (United States)

    Boerneke, Mark A; Dibrov, Sergey M; Hermann, Thomas

    2016-03-14

    RNA nanotechnology uses RNA structural motifs to build nanosized architectures that assemble through selective base-pair interactions. Herein, we report the crystal-structure-guided design of highly stable RNA nanotriangles that self-assemble cooperatively from short oligonucleotides. The crystal structure of an 81 nucleotide nanotriangle determined at 2.6 Å resolution reveals the so-far smallest circularly closed nanoobject made entirely of double-stranded RNA. The assembly of the nanotriangle architecture involved RNA corner motifs that were derived from ligand-responsive RNA switches, which offer the opportunity to control self-assembly and dissociation.

  13. Engineering Design Optimization Based on Intelligent Response Surface Methodology

    Institute of Scientific and Technical Information of China (English)

    SONG Guo-hui; WU Yu; LI Cong-xin

    2008-01-01

    An intelligent response surface methodology (IRSM) was proposed to achieve the most competitivemetal forming products, in which artificial intelligence technologies are introduced into the optimization process.It is used as simple and inexpensive replacement for computationally expensive simulation model. In IRSM,the optimal design space can be reduced greatly without any prior information about function distribution.Also, by identifying the approximation error region, new design points can be supplemented correspondingly toimprove the response surface model effectively. The procedure is iterated until the accuracy reaches the desiredthreshold value. Thus, the global optimization can be performed based on this substitute model. Finally, wepresent an optimization design example about roll forming of a "U" channel product.

  14. Alloy Design Workbench-Surface Modeling Package Developed

    Science.gov (United States)

    Abel, Phillip B.; Noebe, Ronald D.; Bozzolo, Guillermo H.; Good, Brian S.; Daugherty, Elaine S.

    2003-01-01

    NASA Glenn Research Center's Computational Materials Group has integrated a graphical user interface with in-house-developed surface modeling capabilities, with the goal of using computationally efficient atomistic simulations to aid the development of advanced aerospace materials, through the modeling of alloy surfaces, surface alloys, and segregation. The software is also ideal for modeling nanomaterials, since surface and interfacial effects can dominate material behavior and properties at this level. Through the combination of an accurate atomistic surface modeling methodology and an efficient computational engine, it is now possible to directly model these types of surface phenomenon and metallic nanostructures without a supercomputer. Fulfilling a High Operating Temperature Propulsion Components (HOTPC) project level-I milestone, a graphical user interface was created for a suite of quantum approximate atomistic materials modeling Fortran programs developed at Glenn. The resulting "Alloy Design Workbench-Surface Modeling Package" (ADW-SMP) is the combination of proven quantum approximate Bozzolo-Ferrante-Smith (BFS) algorithms (refs. 1 and 2) with a productivity-enhancing graphical front end. Written in the portable, platform independent Java programming language, the graphical user interface calls on extensively tested Fortran programs running in the background for the detailed computational tasks. Designed to run on desktop computers, the package has been deployed on PC, Mac, and SGI computer systems. The graphical user interface integrates two modes of computational materials exploration. One mode uses Monte Carlo simulations to determine lowest energy equilibrium configurations. The second approach is an interactive "what if" comparison of atomic configuration energies, designed to provide real-time insight into the underlying drivers of alloying processes.

  15. Design of a robust superhydrophobic surface: thermodynamic and kinetic analysis

    CERN Document Server

    Sarkar, Anjishnu

    2014-01-01

    The design of a robust superhydrophobic surface is a widely pursued topic.While many investigations are limited to applications with high impact velocities (for raindrops of the order of a few m/s), the essence of robustness is yet to be analyzed for applications involving quasi-static liquid transfer.To achieve robustness with high impact velocities, the surface parameters (geometrical details, chemistry) have to be selected from a narrow range of permissible values, which often entail additional manufacturing costs.From the dual perspectives of thermodynamics and mechanics, we analyze the significance of robustness for quasi-static drop impact, and present the range of permissible surface characteristics.For surfaces with a Youngs contact angle greater than 90{\\deg} and square micropillar geometry, we show that robustness can be enforced when an intermediate wetting state (sagged state) impedes transition to a wetted state (Wenzel state).From the standpoint of mechanics, we use available scientific data to ...

  16. V-Ray my way a practical designer's guide to creating realistic imagery using V-Ray & 3ds Max

    CERN Document Server

    Wylde, Lee

    2014-01-01

    V-Ray My Way: A Practical Designers Guide to Creating Realistic Imagery Using V-Ray & 3ds Max is a practical, hands-on guide to creating some of the most stunning computer-generated images possible. It caters to the design masses; architects, engineers, interior designers, industrial designers, photographers, and enthusiasts will find this book essential in their quest to express themselves through visual communication. V-Ray My Way is an accumulation of 13 years of experimental experience and will have you creating content within minutes, help grow your company, help develop

  17. Nano magnetic vortex wall guide

    Directory of Open Access Journals (Sweden)

    H. Y. Yuan

    2015-11-01

    Full Text Available A concept of nano magnetic vortex wall guide is introduced. Two architectures are proposed. The first one is properly designed superlattices while the other one is bilayer nanostrips. The concept is verified by micromagnetic simulations. Both guides can prevent the vortex core in a magnetic vortex wall from colliding with sample surface so that the information stored in the vortex core can be preserved during its transportation from one location to another one through the guides.

  18. Designing Self-Healing Superhydrophobic Surfaces with Exceptional Mechanical Durability.

    Science.gov (United States)

    Golovin, Kevin; Boban, Mathew; Mabry, Joseph M; Tuteja, Anish

    2017-03-29

    The past decade saw a drastic increase in the understanding and applications of superhydrophobic surfaces (SHSs). Water beads up and effortlessly rolls off a SHS due to its combination of low surface energy and texture. Whether being used for drag reduction, stain repellency, self-cleaning, fog harvesting, or heat transfer applications (to name a few), the durability of a SHS is critically important. Although a handful of purportedly durable SHSs have been reported, there are still no criteria available for systematically designing a durable SHS. In the first part of this work, we discuss two new design parameters that can be used to develop mechanically durable SHSs via the spray coating of different binders and fillers. These parameters aid in the rational selection of material components and allow one to predict the capillary resistance to wetting of any SHS from a simple topographical analysis. We show that not all combinations of sprayable components generate SHSs, and mechanically durable components do not necessarily generate mechanically durable SHSs. Moreover, even the most durable SHSs can eventually become damaged. In the second part, utilizing our new parameters, we design and fabricate physically and chemically self-healing SHSs. The most promising surface is fabricated from a fluorinated polyurethane elastomer (FPU) and the extremely hydrophobic small molecule 1H,1H,2H,2H-heptadecafluorodecyl polyhedral oligomeric silsesquioxane (F-POSS). A sprayed FPU/F-POSS surface can recover its superhydrophobicity even after being abraded, scratched, burned, plasma-cleaned, flattened, sonicated, and chemically attacked.

  19. Conformal array design on arbitrary polygon surface with transformation optics

    Directory of Open Access Journals (Sweden)

    Li Deng

    2016-06-01

    Full Text Available A transformation-optics based method to design a conformal antenna array on an arbitrary polygon surface is proposed and demonstrated in this paper. This conformal antenna array can be adjusted to behave equivalently as a uniformly spaced linear array by applying an appropriate transformation medium. An typical example of general arbitrary polygon conformal arrays, not limited to circular array, is presented, verifying the proposed approach. In summary, the novel arbitrary polygon surface conformal array can be utilized in array synthesis and beam-forming, maintaining all benefits of linear array.

  20. Conformal array design on arbitrary polygon surface with transformation optics

    Science.gov (United States)

    Deng, Li; Wu, Yongle; Hong, Weijun; Zhu, Jianfeng; Peng, Biao; Li, Shufang

    2016-06-01

    A transformation-optics based method to design a conformal antenna array on an arbitrary polygon surface is proposed and demonstrated in this paper. This conformal antenna array can be adjusted to behave equivalently as a uniformly spaced linear array by applying an appropriate transformation medium. An typical example of general arbitrary polygon conformal arrays, not limited to circular array, is presented, verifying the proposed approach. In summary, the novel arbitrary polygon surface conformal array can be utilized in array synthesis and beam-forming, maintaining all benefits of linear array.

  1. Facile identification of dual FLT3-Aurora A inhibitors: a computer-guided drug design approach.

    Science.gov (United States)

    Chang Hsu, Yung; Ke, Yi-Yu; Shiao, Hui-Yi; Lee, Chieh-Chien; Lin, Wen-Hsing; Chen, Chun-Hwa; Yen, Kuei-Jung; Hsu, John T-A; Chang, Chungming; Hsieh, Hsing-Pang

    2014-05-01

    Computer-guided drug design is a powerful tool for drug discovery. Herein we disclose the use of this approach for the discovery of dual FMS-like receptor tyrosine kinase-3 (FLT3)-Aurora A inhibitors against cancer. An Aurora hit compound was selected as a starting point, from which 288 virtual molecules were screened. Subsequently, some of these were synthesized and evaluated for their capacity to inhibit FLT3 and Aurora kinase A. To further enhance FLT3 inhibition, structure-activity relationship studies of the lead compound were conducted through a simplification strategy and bioisosteric replacement, followed by the use of computer-guided drug design to prioritize molecules bearing a variety of different terminal groups in terms of favorable binding energy. Selected compounds were then synthesized, and their bioactivity was evaluated. Of these, one novel inhibitor was found to exhibit excellent inhibition of FLT3 and Aurora kinase A and exert a dramatic antiproliferative effect on MOLM-13 and MV4-11 cells, with an IC50 value of 7 nM. Accordingly, it is considered a highly promising candidate for further development.

  2. SOLCOST-PASSIVE solar energy design program: User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    1980-09-01

    The SOLCOST-PASSIVE solar energy design program is a public domain interactive computer design tool intended for use by non-thermal specialists to size passive solar systems with a methodology based on the Los Alamos Solar Load Ratio method. A life cycle savings analysis is included in the program. An overview of SOLCOST-PASSIVE capabilities and the Solar Load Ratio method which it is based on is presented. A detailed guide to the SOLCOST-PASSIVE input parameters is given. Sample problems showing typical execution sessions and the resulting SOLCOST-PASSIVE output are included. Appendices A thru D provide details on the SLR method and the life cycle savings methodology of SOLCOST-PASSIVE. (MHR)

  3. Design and fabrication of light-guiding plate for a photobioreactor that utilizes sunlight

    Science.gov (United States)

    Lim, Hyon-Chol; Kim, Hun; Jang, Kyungmin; Kim, Jae-Young; Baek, Joon-Hyuck; Yang, Seung-Jin; Jeong, Sang-Hwa; Park, Jong-Rak

    2015-10-01

    We present the results of the optical design and fabrication of a light-guiding plate (LGP) that utilizes sunlight to be adopted as an illumination system for photobioreactors. A solar daylighting system was employed as the light source for the LGP. We modeled the light sources (optical fiber exit ports of the solar daylighting system), a reflection film, and LGP patterns. An LGP (1000 mm × 500 mm × 10 mm) was designed and fabricated using a computerized numerical control machine. It was optimized for the average deviation of the illuminance distribution by varying the maximum pattern spacing, minimum pattern spacing, and spacing constant of the pattern spacing function expressed in the form of an exponential function. Average illuminance and uniformity of the illuminance distribution of the fabricated LGP were measured to be 8174 lx (photon flux density: 122.0 μΕ m-2 s-1) and 90.0 %, respectively.

  4. Neural Network Control-Based Drive Design of Servomotor and Its Application to Automatic Guided Vehicle

    Directory of Open Access Journals (Sweden)

    Ming-Shyan Wang

    2015-01-01

    Full Text Available An automatic guided vehicle (AGV is extensively used for productions in a flexible manufacture system with high efficiency and high flexibility. A servomotor-based AGV is designed and implemented in this paper. In order to steer the AGV to go along a predefined path with corner or arc, the conventional proportional-integral-derivative (PID control is used in the system. However, it is difficult to tune PID gains at various conditions. As a result, the neural network (NN control is considered to assist the PID control for gain tuning. The experimental results are first provided to verify the correctness of the neural network plus PID control for 400 W-motor control system. Secondly, the AGV includes two sets of the designed motor systems and CAN BUS transmission so that it can move along the straight line and curve paths shown in the taped videos.

  5. Electron work function-a promising guiding parameter for material design.

    Science.gov (United States)

    Lu, Hao; Liu, Ziran; Yan, Xianguo; Li, Dongyang; Parent, Leo; Tian, Harry

    2016-04-14

    Using nickel added X70 steel as a sample material, we demonstrate that electron work function (EWF), which largely reflects the electron behavior of materials, could be used as a guide parameter for material modification or design. Adding Ni having a higher electron work function to X70 steel brings more "free" electrons to the steel, leading to increased overall work function, accompanied with enhanced e(-)-nuclei interactions or higher atomic bond strength. Young's modulus and hardness increase correspondingly. However, the free electron density and work function decrease as the Ni content is continuously increased, accompanied with the formation of a second phase, FeNi3, which is softer with a lower work function. The decrease in the overall work function corresponds to deterioration of the mechanical strength of the steel. It is expected that EWF, a simple but fundamental parameter, may lead to new methodologies or supplementary approaches for metallic materials design or tailoring on a feasible electronic base.

  6. Designing an elliptical supermirror guide for the high-pressure material science beamline of J-PARC

    Science.gov (United States)

    Arima, Hiroshi; Komatsu, Kazuki; Ikeda, Kazuaki; Hirota, Katsuya; Kagi, Hiroyuki

    2009-02-01

    The design of an elliptical neutron guide for the time-of-flight (TOF) powder diffractometer of the high-pressure material science beamline at J-PARC was optimized using the McStas Monte Carlo simulation program to increase neutron flux for a small sample size. We investigated the analytical design in accordance with some requirements such as the gain factor at the small sample size and sufficient resolution at shorter wavelength of incident neutrons. The intensity and divergence with respect to energy dependence for elliptical guide designs were compared with those for the linearly tapered and straight guides. Optimizing the design of the elliptical guide results in the largest gain below 0.70 Å wavelength and gives constant instrumental resolution greater than 1 Å. The guide can support a flux gain of about 2.2 (high-intensity mode, Δ d/ d of ca. 0.6%) and 1.2 (high-resolution mode; Δ d/ d of ca. 0.5%) greater than 1 Å compared to the beamline of the natural flight path with resolution similar to that provided by the optimized elliptical guide.

  7. Designing an elliptical supermirror guide for the high-pressure material science beamline of J-PARC

    Energy Technology Data Exchange (ETDEWEB)

    Arima, Hiroshi [Geochemical Laboratory, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan)], E-mail: arima.hiroshi@jaea.go.jp; Komatsu, Kazuki [Geochemical Laboratory, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); Ikeda, Kazuaki; Hirota, Katsuya [RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Kagi, Hiroyuki [Geochemical Laboratory, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan)

    2009-02-21

    The design of an elliptical neutron guide for the time-of-flight (TOF) powder diffractometer of the high-pressure material science beamline at J-PARC was optimized using the McStas Monte Carlo simulation program to increase neutron flux for a small sample size. We investigated the analytical design in accordance with some requirements such as the gain factor at the small sample size and sufficient resolution at shorter wavelength of incident neutrons. The intensity and divergence with respect to energy dependence for elliptical guide designs were compared with those for the linearly tapered and straight guides. Optimizing the design of the elliptical guide results in the largest gain below 0.70 A wavelength and gives constant instrumental resolution greater than 1 A. The guide can support a flux gain of about 2.2 (high-intensity mode, {delta}d/d of ca. 0.6%) and 1.2 (high-resolution mode; {delta}d/d of ca. 0.5%) greater than 1 A compared to the beamline of the natural flight path with resolution similar to that provided by the optimized elliptical guide.

  8. Functional Design and Qualification of Surface Tension Propellant Tanks

    Science.gov (United States)

    Figus, C.; Haddad, D.; Ounougha, L.; Autric, J.

    2004-10-01

    During two decades, EADS Astrium has designed and qualified the surface tension device used in the propellant tanks equipping the Eurostar telecommunication satellites platforms. Recent re- orbiting phases of Eurostar E2000 satellites, have allowed to validate those designs and to graveyard the spacecraft with less than 1 kg of propellant left per tank. Moreover, with the emergence of new powerful satellites with full chemical or mixed chemical-plasma propulsion subsystems, EADS Astrium has designed a new larger and improved surface tension propellant tank. Such challenging performances require analyses, and tests in order to assess and confirm the predicted performances. The present article shows the recent development of a new enlarged Eurostar E3000 propellant tanks for Eurostar 3000 satellites and presents the main functional analyses and neutral buoyancy tests results obtained for this new propellant tank These last two years, have contributed to improve this background with the successful graveyard of the first Eurostar spacecraft with less than 1 kg of liquid propellant per tank at the end of the manoeuvre. Moreover, a new enlarged E3000 propellant tank has been designed and qualified in order to cope with the future 12 kW telecom spacecraft applications. This tank designed by EADS-ASTRIUM, is manufactured by EADS-Space transportation. This paper presents the performances and tests results obtained on this new propellant tank.

  9. Optimization of a hybrid electric power system design for large commercial buildings: An application design guide

    Science.gov (United States)

    Lee, Keun

    with the optimization of the hybrid system design (which consists of PV panels and/or wind turbines and/or storage devices for building applications) by developing an algorithm designed to make the system cost effective and energy efficient. Input data includes electrical load demand profile of the buildings, buildings' structural and geographical characteristics, real time pricing of electricity, and the costs of hybrid systems and storage devices. When the electrical load demand profile of a building that is being studied is available, a measured demand profile is directly used as input data. However, if that information is not available, a building's electric load demand is estimated using a developed algorithm based on three large data sources from a public domain, and used as input data. Using the acquired input data, the algorithm of this research is designed and programmed in order to determine the size of renewable components and to minimize the total yearly net cost. This dissertation also addresses the parametric sensitivity analysis to determine which factors are more significant and are expected to produce useful guidelines in the decision making process. An engineered and more practical, simplified solution has been provided for the optimized design process.

  10. Feasibility study for image-guided kidney surgery: Assessment of required intraoperative surface for accurate physical to image space registrations

    Science.gov (United States)

    Benincasa, Anne B.; Clements, Logan W.; Herrell, S. Duke; Galloway, Robert L.

    2008-01-01

    A notable complication of applying current image-guided surgery techniques of soft tissue to kidney resections (nephrectomies) is the limited field of view of the intraoperative kidney surface. This limited view constrains the ability to obtain a sufficiently geometrically descriptive surface for accurate surface-based registrations. The authors examined the effects of the limited view by using two orientations of a kidney phantom to model typical laparoscopic and open partial nephrectomy views. Point-based registrations, using either rigidly attached markers or anatomical landmarks as fiducials, served as initial alignments for surface-based registrations. Laser range scanner (LRS) obtained surfaces were registered to the phantom’s image surface using a rigid iterative closest point algorithm. Subsets of each orientation’s LRS surface were used in a robustness test to determine which parts of the surface yield the most accurate registrations. Results suggest that obtaining accurate registrations is a function of the percentage of the total surface and of geometric surface properties, such as curvature. Approximately 28% of the total surface is required regardless of the location of that surface subset. However, that percentage decreases when the surface subset contains information from opposite ends of the surface and∕or unique anatomical features, such as the renal artery and vein. PMID:18841875

  11. Design of Matched Absorbing Layers for Surface Plasmon-Polaritons

    Directory of Open Access Journals (Sweden)

    Sergio de la Cruz

    2012-01-01

    Full Text Available We describe a procedure for designing metal-metal boundaries for the strong attenuation of surface plasmon-polaritons without the introduction of reflections or scattering effects. Solutions associated with different sets of matching materials are found. To illustrate the results and the consequences of adopting different solutions, we present calculations based on an integral equation formulation for the scattering problem and the use of a nonlocal impedance boundary condition.

  12. Linkage design effect on the reliability of surface micromachined microengines driving a load

    Energy Technology Data Exchange (ETDEWEB)

    Tanner, D.M.; Peterson, K.A.; Irwin, L.W.; Tangyunyong, P.; Miller, W.M.; Eaton, W.P.; Smith, N.F.; Rodgers, M.S.

    1998-08-01

    The reliability of microengines is a function of the design of the mechanical linkage used to connect the electrostatic actuator to the drive. The authors have completed a series of reliability stress tests on surface micromachined microengines driving an inertial load. In these experiments, the authors used microengines that had pin mechanisms with guides connecting the drive arms to the electrostatic actuators. Comparing this data to previous results using flexure linkages revealed that the pin linkage design was less reliable. The devices were stressed to failure at eight frequencies, both above and below the measured resonance frequency of the microengine. Significant amounts of wear debris were observed both around the hub and pin joint of the drive gear. Additionally, wear tracks were observed in the area where the moving shuttle rubbed against the guides of the pin linkage. At each frequency, they analyzed the statistical data yielding a lifetime (t{sub 50}) for median cycles to failure and {sigma}, the shape parameter of the distribution. A model was developed to describe the failure data based on fundamental wear mechanisms and forces exhibited in mechanical resonant systems. The comparison to the model will be discussed.

  13. Using surface markers for MRI guided breast conserving surgery: a feasibility survey

    Science.gov (United States)

    Ebrahimi, Mehran; Siegler, Peter; Modhafar, Amen; Holloway, Claire M. B.; Plewes, Donald B.; Martel, Anne L.

    2014-04-01

    Breast MRI is frequently performed prior to breast conserving surgery in order to assess the location and extent of the lesion. Ideally, the surgeon should also be able to use the image information during surgery to guide the excision and this requires that the MR image is co-registered to conform to the patient’s position on the operating table. Recent progress in MR imaging techniques has made it possible to obtain high quality images of the patient in the supine position which significantly reduces the complexity of the registration task. Surface markers placed on the breast during imaging can be located during surgery using an external tracking device and this information can be used to co-register the images to the patient. There remains the problem that in most clinical MR scanners the arm of the patient has to be placed parallel to the body whereas the arm is placed perpendicular to the patient during surgery. The aim of this study is to determine the accuracy of co-registration based on a surface marker approach and, in particular, to determine what effect the difference in a patient’s arm position makes on the accuracy of tumour localization. Obtaining a second MRI of the patient where the patient’s arm is perpendicular to body axes (operating room position) is not possible. Instead we obtain a secondary MRI scan where the patient’s arm is above the patient’s head to validate the registration. Five patients with enhancing lesions ranging from 1.5 to 80 cm3 in size were imaged using contrast enhanced MRI with their arms in two positions. A thin-plate spline registration scheme was used to match these two configurations. The registration algorithm uses the surface markers only and does not employ the image intensities. Tumour outlines were segmented and centre of mass (COM) displacement and Dice measures of lesion overlap were calculated. The relationship between the number of markers used and the COM-displacement was also studied. The lesion COM

  14. Multiple focused EMAT designs for improved surface breaking defect characterization

    Science.gov (United States)

    Thring, C. B.; Fan, Y.; Edwards, R. S.

    2017-02-01

    Ultrasonic Rayleigh waves can be employed for the detection of surface breaking defects such as rolling contact fatigue and stress corrosion cracking. Electromagnetic Acoustic Transducers (EMATs) are well suited to this technique as they can directly generate Rayleigh waves within the sample without the requirement for wedges, and they are robust and inexpensive compared to laser ultrasonics. Three different EMAT coil types have been developed, and these are compared to assess their ability to detect and characterize small (down to 0.5 mm depth, 1 mm diameter) surface breaking defects in aluminium. These designs are: a pair of linear meander coils used in a pseudo-pulse-echo mode, a pair of focused meander coils also used in pseudo-pulse-echo mode, and a pair of focused racetrack coils used in pitch-catch mode. The linear meander coils are able to detect most of the defects tested, but have a much lower signal to noise ratio and give limited sizing information. The focused meander coils and the focused racetrack coils can detect all defects tested, but have the advantage that they can also characterize the defect sizes on the sample surface, and have a stronger sensitivity at their focal point. Measurements using all three EMAT designs are presented and compared for high resolution imaging of surface-breaking defects.

  15. Comparison of connective tissue graft and guided tissue regeneration in covering root surfaces

    Directory of Open Access Journals (Sweden)

    LotfazarM.

    2002-08-01

    Full Text Available There are many researches evaluation different methods for covering the root surface. In the most of these studies, type I and II of Miller treatment had been searched. The purpose of this study was a comparison between connective tissue graft (CTG and guided tissue regeneration (GTR with a collagen membrane in the treatment of gingival recession defects (Miller class III. Six patients, each contributing a pair of Miller class III buccal gingival recessions, were treated. The clinical measurements were obtained at baseline and 1,2,4,6,12,18 months after surgery. Statistical analysis were performed using paired t-test between periods (baseline versus 6 months and baseline versus 18 months within each treatment group and also between treatment groups before treatment and 6, 12 and 18 months after the treatment. The treatments were compared by a triple analysis of variance along the time (treatment, patient, time. Both CTG and GTR with a bioabsorbable membrane demonstrated significant clinical and esthetic improvement for gingival recession coverage. The CTG and GTR procedures had mean root coverage of 55% and 47.5% respectively, in the end of study. The CTG group was statistically better than GTR for recession depth, recession width and keratinized tissue width. Also, passing the time (18 months as a distinct factor of treatment procedures was effective in increasing of clinical attachment level and keratinized tissue width.

  16. Design of a Three Surfaces R/C Aircraft Model

    Directory of Open Access Journals (Sweden)

    D. P. Coiro

    2002-01-01

    Full Text Available Design of a three lifting surfaces radio-controlled model has been carried out at Dipartimento di Progettazione Aeronautica (DPA by the authors in the last year. The model is intended to be a UAV prototype and is now under construction. The main goal of this small aircraft's design is to check the influence of the canard surface on the aircraft's aerodynamic characteristics and flight behavior, especially at high angles of attack. The aircraft model is also intended to be a flying platform to test sensors, measurement and acquisition systems for research purposes and a valid and low-cost teaching instrument for flight dynamics and flight maneuvering. The aircraft has been designed to fly with and without canard, and all problems relative to aircraft balance and stability have been carefully analyzed and solved. The innovative configuration and the mixed wooden-composite material structure has been obtained with very simple shapes and all the design is focused on realizing a low-cost model. A complete aerodynamic analysis of the configuration up to high angles of attack and a preliminary aircraft stability and performance prediction will be presented.

  17. On the criteria guiding the design of the upper electron-cyclotron launcher for ITER

    Directory of Open Access Journals (Sweden)

    Poli E.

    2015-01-01

    Full Text Available Electron cyclotron waves injected from an antenna located in the upper part of the vessel will be employed in ITER to controlMHD instabilities, particularly neoclassical tearingmodes (NTMs. The derivation of the NTM stabilization criteria used up to now to guide the optimization of the launcher is reviewed in this paper and their range of validity elucidated. Possible effects leading to a deterioration of the predicted performance through a broadening of the EC deposition profile are discussed. The most detrimental effect will likely be the scattering of the EC beams from density fluctuations, resulting in a beam broadening in the 100% range. The combined impact of these effects with that of beam misalignment (with respect to the targeted surface is discussed for a time slice of the standard Q = 10 H-mode scenario.

  18. New U.S. pavement design guide will have major impact in Canada

    Energy Technology Data Exchange (ETDEWEB)

    Hein, D.

    2002-03-31

    The potential impacts and benefits that are likely to accrue to Canada with the upcoming release of the 2002 Pavement Design Guide of the American Association of State Highway and Transportation Officials (ASSHTO) are reviewed. The impact will be felt through AASHTO's 2002 mechanistic-empirical design method, a multi-level hierarchical approach based on design data requirements reflecting roadway classification and current roadway use configurations. A significant departure from the previous system is the emphasis on vehicle axle load distribution rather than equivalent single axle loads to evaluate pavement loading over service life. Specific benefits include: (1) consideration of inherent variations in materials, traffic and environmental factors in construction processes facilitating agency managers to be better able to weigh life cycle costs and cash flow in their decision making processes; (2) enhanced cost-responsibility studies through the improved ability to evaluate consequences of new pavement loading conditions; (3) ability of designers to use available and evolving materials ; (4) improved evaluation of premature pavement failures through better diagnostic techniques; and (5) better assessment of the effects of aging and that of the freeze-thaw cycle through better environmental data and analysis.

  19. Guiding science expeditions: The design of a learning environment for project-based science

    Science.gov (United States)

    Polman, Joseph Louis

    Project-based pedagogy has been revived recently as a teaching strategy for promoting students' active engagement in learning science by doing science. Numerous reform efforts have encouraged project-based teaching in high schools, along with a range of supports for its implementation, often including computers and the Internet. History has shown, however, that academic research and new technologies are not enough to effect real change in classrooms. Ultimately, teachers accomplish activity with their students daily in classrooms. Putting the idea of project-based teaching into practice depends on many particulars of teachers' situated work with students. To better understand the complexity of project-based science teaching in schools, I conducted an interpretive case study of one exceptional teacher's work. The teacher devotes all class time after the beginning of the year to open-ended, student-designed Earth Science research projects. Over four years of involvement with the Learning through Collaborative Visualization (CoVis) reform effort, this teacher has developed, implemented, and refined strategies for supporting and guiding students in conducting open-ended inquiry. Through a close examination of the teacher's work supporting student projects, I explore the design issues involved in such an endeavor, including affordances, constraints, and tradeoffs. In particular, I show how time constrains both student and teacher action, how the traditional school culture and grading create stumbling blocks for change, and how conflicting beliefs about teaching and learning undermine the accomplishment of guided inquiry. I also show how Internet tools including Usenet news, email, and the World Wide Web afford students an opportunity to gather and make use of distributed expertise and scientific data resources; how an activity structure, combined with a corresponding structure to the artifact of the final written product, supports student accomplishment of unfamiliar

  20. An Ontology Design Pattern for Surface Water Features

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, Gaurav [Ohio University; Mark, David [University at Buffalo (SUNY); Kolas, Dave [Raytheon BBN Technologies; Varanka, Dalia [U.S. Geological Survey, Rolla, MO; Romero, Boleslo E [University of California, Santa Barbara; Feng, Chen-Chieh [National University of Singapore; Usery, Lynn [U.S. Geological Survey, Rolla, MO; Liebermann, Joshua [Tumbling Walls, LLC; Sorokine, Alexandre [ORNL

    2014-01-01

    Surface water is a primary concept of human experience but concepts are captured in cultures and languages in many different ways. Still, many commonalities can be found due to the physical basis of many of the properties and categories. An abstract ontology of surface water features based only on those physical properties of landscape features has the best potential for serving as a foundational domain ontology. It can then be used to systematically incor-porate concepts that are specific to a culture, language, or scientific domain. The Surface Water ontology design pattern was developed both for domain knowledge distillation and to serve as a conceptual building-block for more complex surface water ontologies. A fundamental distinction is made in this on-tology between landscape features that act as containers (e.g., stream channels, basins) and the bodies of water (e.g., rivers, lakes) that occupy those containers. Concave (container) landforms semantics are specified in a Dry module and the semantics of contained bodies of water in a Wet module. The pattern is imple-mented in OWL, but Description Logic axioms and a detailed explanation is provided. The OWL ontology will be an important contribution to Semantic Web vocabulary for annotating surface water feature datasets. A discussion about why there is a need to complement the pattern with other ontologies, es-pecially the previously developed Surface Network pattern is also provided. Fi-nally, the practical value of the pattern in semantic querying of surface water datasets is illustrated through a few queries and annotated geospatial datasets.

  1. Design and Realization of an Electromagnetic Guiding System for Blind Running Athletes.

    Science.gov (United States)

    Pieralisi, Marco; Petrini, Valerio; Di Mattia, Valentina; Manfredi, Giovanni; De Leo, Alfredo; Scalise, Lorenzo; Russo, Paola; Cerri, Graziano

    2015-07-08

    Nowadays the technologies aimed at improving the quality of life of people affected by visual diseases are quite common; e.g., devices to support walking or reading. Surprisingly, there is a lack of innovative technologies aimed at helping visually impaired athletes during physical activities. An example is represented by blind runners who need to be physically linked to a sighted guide by means of non-stretchable tethers during races; with consequent limitations in terms of performance and independence. This paper wants to investigate the possibility of realizing a system able to guide blind runners along a complex path, paving the way for the realization of an innovative device designed to improve their independence during training or competitions. The system consists of: (1) a mobile unit, which is placed before the runner and generates two "electromagnetic walls" delimiting the way; (2) a receiving unit (worn by the athlete) that provides vibro-tactile warnings every time the user is going outside the safe area so as to encourage him to move toward the central position. The feasibility and the utility of the system proposed are demonstrated by means of tests carried out thanks to the collaboration of a blind volunteer.

  2. Design and Realization of an Electromagnetic Guiding System for Blind Running Athletes

    Directory of Open Access Journals (Sweden)

    Marco Pieralisi

    2015-07-01

    Full Text Available Nowadays the technologies aimed at improving the quality of life of people affected by visual diseases are quite common; e.g., devices to support walking or reading. Surprisingly; there is a lack of innovative technologies aimed at helping visually impaired athletes during physical activities. An example is represented by blind runners who need to be physically linked to a sighted guide by means of non-stretchable tethers during races; with consequent limitations in terms of performance and independence. This paper wants to investigate the possibility of realizing a system able to guide blind runners along a complex path; paving the way for the realization of an innovative device designed to improve their independence during training or competitions. The system consists of: (1 A mobile unit; which is placed before the runner and generates two “electromagnetic walls” delimiting the way; (2 a receiving unit (worn by the athlete that provides vibro-tactile warnings every time the user is going outside the safe area so as to encourage him to move toward the central position. The feasibility and the utility of the system proposed are demonstrated by means of tests carried out thanks to the collaboration of a blind volunteer.

  3. e-Learning in medical education Guide 32 Part 2: Technology, management and design.

    Science.gov (United States)

    Masters, Ken; Ellaway, Rachel

    2008-06-01

    With e-learning now part of the medical education mainstream, both educational and practical technical and informatics skills have become an essential part of the medical teacher's portfolio. The Guide is intended to help teachers develop their skills in working in the new online educational environments, and to ensure that they appreciate the wider changes and developments that accompany this 'information revolution'. The Guide is divided into two parts, of which this is the second. The first part introduced the basic concepts of e-learning, e-teaching, and e-assessment, the day-to-day issues of e-learning, looking both at theoretical concepts and practical implementation issues. This second part covers topics such as practical knowledge of the forms of technology used in e-learning, the behaviours of teachers and learners in online environments and the design of e-learning content and activities. It also deals with broader concepts of the politics and psychology of e-learning, as well as many of its ethical, legal and economical dimensions, and it ends with a review of emerging forms and directions in e-learning in medical education.

  4. How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design.

    Science.gov (United States)

    Pancera, Marie; Changela, Anita; Kwong, Peter D

    2017-05-01

    An HIV-1 vaccine that elicits broadly neutralizing antibodies (bNAbs) remains to be developed. Here, we review how knowledge of bNAbs and HIV-1 entry mechanism is guiding the structure-based design of vaccine immunogens and immunization regimens. Isolation of bNAbs from HIV-1-infected donors has led to an unprecedented understanding of the sites of vulnerability that these antibodies target on the HIV-1 envelope (Env) as well as of the immunological pathways that these antibody lineages follow to develop broad and potent neutralization. Sites of vulnerability, however, reside in the context of diverse Env conformations required for HIV-1 entry, including a prefusion-closed state, a single-CD4-bound intermediate, a three-CD4-bound intermediate, a prehairpin intermediate and postfusion states, and it is not always clear which structural state optimally presents a particular site of vulnerability in the vaccine context. Furthermore, detailed knowledge of immunological pathways has led to debate among vaccine developers as to how much of the natural antibody-developmental pathway immunogens should mimic, ranging from only the recognized epitope to multiple antigens from the antibody-virus coevolution process. A plethora of information on bNAbs is guiding HIV-1-vaccine development. We highlight consideration of the appropriate structural context from the HIV-1-entry mechanism and extraordinary progress with replicating template B-cell ontogenies.

  5. Feasibility study for image guided kidney surgery: assessment of required intraoperative surface for accurate image to physical space registrations

    Science.gov (United States)

    Benincasa, Anne B.; Clements, Logan W.; Herrell, S. Duke; Chang, Sam S.; Cookson, Michael S.; Galloway, Robert L.

    2006-03-01

    Currently, the removal of kidney tumor masses uses only direct or laparoscopic visualizations, resulting in prolonged procedure and recovery times and reduced clear margin. Applying current image guided surgery (IGS) techniques, as those used in liver cases, to kidney resections (nephrectomies) presents a number of complications. Most notably is the limited field of view of the intraoperative kidney surface, which constrains the ability to obtain a surface delineation that is geometrically descriptive enough to drive a surface-based registration. Two different phantom orientations were used to model the laparoscopic and traditional partial nephrectomy views. For the laparoscopic view, fiducial point sets were compiled from a CT image volume using anatomical features such as the renal artery and vein. For the traditional view, markers attached to the phantom set-up were used for fiducials and targets. The fiducial points were used to perform a point-based registration, which then served as a guide for the surface-based registration. Laser range scanner (LRS) obtained surfaces were registered to each phantom surface using a rigid iterative closest point algorithm. Subsets of each phantom's LRS surface were used in a robustness test to determine the predictability of their registrations to transform the entire surface. Results from both orientations suggest that about half of the kidney's surface needs to be obtained intraoperatively for accurate registrations between the image surface and the LRS surface, suggesting the obtained kidney surfaces were geometrically descriptive enough to perform accurate registrations. This preliminary work paves the way for further development of kidney IGS systems.

  6. Analysis and Design of Vertical Cavity Surface Emitting Lasers

    Science.gov (United States)

    Yu, S. F.

    2003-08-01

    A practical, hands-on guidebook for the efficient modeling of VCSELs Vertical Cavity Surface Emitting Lasers (VCSELs) are a unique type of semiconductor laser whose optical output is vertically emitted from the surface as opposed to conventional edge-emitting semiconductor lasers. Complex in design and expensive to produce, VCSELs nevertheless represent an already widely used laser technology that promises to have even more significant applications in the future. Although the research has accelerated, there have been relatively few books written on this important topic. Analysis and Design of Vertical Cavity Surface Emitting Lasers seeks to encapsulate this growing body of knowledge into a single, comprehensive reference that will be of equal value for both professionals and academics in the field. The author, a recognized expert in the field of VCSELs, attempts to clarify often conflicting assumptions in order to help readers achieve the simplest and most efficient VCSEL models for any given problem. Highlights of the text include: * A clear and comprehensive theoretical treatment of VCSELs * Detailed derivations for understanding the operational principles of VCSELs * Mathematical models for the investigation of electrical, optical, and thermal properties of VCSELs * Case studies on the mathematical modeling of VCSELs and the implementation of simulation programs

  7. Development of the Advanced Energy Design Guide for K-12 Schools -- 50% Energy Savings

    Energy Technology Data Exchange (ETDEWEB)

    Bonnema, E.; Leach, M.; Pless, S.; Torcellini, P.

    2013-02-01

    This Technical Support Document (TSD) describes the process and methodology for the development of the Advanced Energy Design Guide for K-12 School Buildings: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-K12) (ASHRAE et al. 2011a). The AEDG-K12 provides recommendations for achieving 50% whole-building energy savings in K-12 schools over levels achieved by following ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings (Standard 90.1-2004) (ASHRAE 2004b). The AEDG-K12 was developed in collaboration with the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy (DOE).

  8. Structure-guided design of selective Epac1 and Epac2 agonists.

    Directory of Open Access Journals (Sweden)

    Frank Schwede

    2015-01-01

    Full Text Available The second messenger cAMP is known to augment glucose-induced insulin secretion. However, its downstream targets in pancreatic β-cells have not been unequivocally determined. Therefore, we designed cAMP analogues by a structure-guided approach that act as Epac2-selective agonists both in vitro and in vivo. These analogues activate Epac2 about two orders of magnitude more potently than cAMP. The high potency arises from increased affinity as well as increased maximal activation. Crystallographic studies demonstrate that this is due to unique interactions. At least one of the Epac2-specific agonists, Sp-8-BnT-cAMPS (S-220, enhances glucose-induced insulin secretion in human pancreatic cells. Selective targeting of Epac2 is thus proven possible and may be an option in diabetes treatment.

  9. PERFORMANCE ANALYSIS AND KINEMATIC DESIGN OF PURE TRANSLATIONAL PARALLEL MECHANISM WITH VERTICAL GUIDE-WAYS

    Institute of Scientific and Technical Information of China (English)

    LI Jianfeng; WANG Xinhua; FEI Renyuan; LIU Dezhong; FAN Jinhong

    2006-01-01

    Performance analysis and kinematic design of the 3-PUU pure translational parallel mechanism with vertical guide-ways are investigated. Two novel performance indices, the critical slider stroke and the main section area of workspace, are defined; The expressions of two other indices, i.e.the global dexterity and global force transfer ratio are revised based on the main section of workspace.Using these indices, performance changes versus the varieties of dimensional parameters of mechanism are investigated in detail and the graphic descriptions of change tendencies of the performance indices are illustrated. By means of these obtained graphic descriptions, kinematic parameters for the 3-PUU pure translational parallel mechanism with better characteristics can be directly acquired.

  10. Technical Support Document: Development of the Advanced Energy Design Guide for Large Hospitals - 50% Energy Savings

    Energy Technology Data Exchange (ETDEWEB)

    Bonnema, E.; Leach, M.; Pless, S.

    2013-06-01

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Large Hospitals: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-LH) ASHRAE et al. (2011b). The AEDG-LH is intended to provide recommendations for achieving 50% whole-building energy savings in large hospitals over levels achieved by following Standard 90.1-2004. The AEDG-LH was created for a 'standard' mid- to large-size hospital, typically at least 100,000 ft2, but the strategies apply to all sizes and classifications of new construction hospital buildings. Its primary focus is new construction, but recommendations may be applicable to facilities undergoing total renovation, and in part to many other hospital renovation, addition, remodeling, and modernization projects (including changes to one or more systems in existing buildings).

  11. Computational design of protein interactions: designing proteins that neutralize influenza by inhibiting its hemagglutinin surface protein

    Science.gov (United States)

    Fleishman, Sarel

    2012-02-01

    Molecular recognition underlies all life processes. Design of interactions not seen in nature is a test of our understanding of molecular recognition and could unlock the vast potential of subtle control over molecular interaction networks, allowing the design of novel diagnostics and therapeutics for basic and applied research. We developed the first general method for designing protein interactions. The method starts by computing a region of high affinity interactions between dismembered amino acid residues and the target surface and then identifying proteins that can harbor these residues. Designs are tested experimentally for binding the target surface and successful ones are affinity matured using yeast cell surface display. Applied to the conserved stem region of influenza hemagglutinin we designed two unrelated proteins that, following affinity maturation, bound hemagglutinin at subnanomolar dissociation constants. Co-crystal structures of hemagglutinin bound to the two designed binders were within 1Angstrom RMSd of their models, validating the accuracy of the design strategy. One of the designed proteins inhibits the conformational changes that underlie hemagglutinin's cell-invasion functions and blocks virus infectivity in cell culture, suggesting that such proteins may in future serve as diagnostics and antivirals against a wide range of pathogenic influenza strains. We have used this method to obtain experimentally validated binders of several other target proteins, demonstrating the generality of the approach. We discuss the combination of modeling and high-throughput characterization of design variants which has been key to the success of this approach, as well as how we have used the data obtained in this project to enhance our understanding of molecular recognition. References: Science 332:816 JMB, in press Protein Sci 20:753

  12. Designing nanomaterials to maximize performance and minimize undesirable implications guided by the Principles of Green Chemistry.

    Science.gov (United States)

    Gilbertson, Leanne M; Zimmerman, Julie B; Plata, Desiree L; Hutchison, James E; Anastas, Paul T

    2015-08-21

    The Twelve Principles of Green Chemistry were first published in 1998 and provide a framework that has been adopted not only by chemists, but also by design practitioners and decision-makers (e.g., materials scientists and regulators). The development of the Principles was initially motivated by the need to address decades of unintended environmental pollution and human health impacts from the production and use of hazardous chemicals. Yet, for over a decade now, the Principles have been applied to the synthesis and production of engineered nanomaterials (ENMs) and the products they enable. While the combined efforts of the global scientific community have led to promising advances in the field of nanotechnology, there remain significant research gaps and the opportunity to leverage the potential global economic, societal and environmental benefits of ENMs safely and sustainably. As such, this tutorial review benchmarks the successes to date and identifies critical research gaps to be considered as future opportunities for the community to address. A sustainable material design framework is proposed that emphasizes the importance of establishing structure-property-function (SPF) and structure-property-hazard (SPH) relationships to guide the rational design of ENMs. The goal is to achieve or exceed the functional performance of current materials and the technologies they enable, while minimizing inherent hazard to avoid risk to human health and the environment at all stages of the life cycle.

  13. Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients

    Science.gov (United States)

    Wang, Conan K.; Northfield, Susan E.; Colless, Barbara; Chaousis, Stephanie; Hamernig, Ingrid; Lohman, Rink-Jan; Nielsen, Daniel S.; Schroeder, Christina I.; Liras, Spiros; Price, David A.; Fairlie, David P.; Craik, David J.

    2014-01-01

    Enhancing the oral bioavailability of peptide drug leads is a major challenge in drug design. As such, methods to address this challenge are highly sought after by the pharmaceutical industry. Here, we propose a strategy to identify appropriate amides for N-methylation using temperature coefficients measured by NMR to identify exposed amides in cyclic peptides. N-methylation effectively caps these amides, modifying the overall solvation properties of the peptides and making them more membrane permeable. The approach for identifying sites for N-methylation is a rapid alternative to the elucidation of 3D structures of peptide drug leads, which has been a commonly used structure-guided approach in the past. Five leucine-rich peptide scaffolds are reported with selectively designed N-methylated derivatives. In vitro membrane permeability was assessed by parallel artificial membrane permeability assay and Caco-2 assay. The most promising N-methylated peptide was then tested in vivo. Here we report a novel peptide (15), which displayed an oral bioavailability of 33% in a rat model, thus validating the design approach. We show that this approach can also be used to explain the notable increase in oral bioavailability of a somatostatin analog. PMID:25416591

  14. The Effect of Femoral Cutting Guide Design Improvements for Patient-Specific Instruments

    Directory of Open Access Journals (Sweden)

    Oh-Ryong Kwon

    2015-01-01

    Full Text Available Although the application of patient-specific instruments (PSI for total knee arthroplasty (TKA increases the cost of the surgical procedure, PSI may reduce operative time and improve implant alignment, which could reduce the number of revision surgeries. We report our experience with TKA using PSI techniques in 120 patients from March to December 2014. PSI for TKA were created from data provided by computed tomography (CT scans or magnetic resonance imaging (MRI; which imaging technology is more reliable for the PSI technique remains unclear. In the first 20 patients, the accuracy of bone resection and PSI stability were compared between CT and MRI scans with presurgical results as a reference; MRI produced better results. In the second and third groups, each with 50 patients, the results of bone resection and stability were compared in MRI scans with respect to the quality of scanning due to motion artifacts and experienced know-how in PSI design, respectively. The optimized femoral cutting guide design for PSI showed the closest outcomes in bone resection and PSI stability with presurgical data. It is expected that this design could be a reasonable guideline in PSI.

  15. Deployment Guide

    Science.gov (United States)

    1994-02-01

    family/unit briefings (to include POA/wills/ consumer law /insurance war clauses) - Provide fill-in-blank sheets to send coordinators of pre- deployment...services. 2. SGLI designations and "By Law" implications. 3. Wills for both spouses. 4. Powers of Attorney. 5. Consumer law issues. 1-7 B. Typically...Relief Act JA 261 Real Property Guide JA 262 Wills Guide JA 263 Family Law Guide JA 265 Consumer Law Guide JA 267 Legal Assistance Office Directory

  16. Design and surface immobilization of short anti-biofilm peptides.

    Science.gov (United States)

    Mishra, Biswajit; Lushnikova, Tamara; Golla, Radha M; Wang, Xiuqing; Wang, Guangshun

    2017-02-01

    Short antimicrobial peptides are essential to keep us healthy and their lasting potency can inspire the design of new types of antibiotics. This study reports the design of a family of eight-residue tryptophan-rich peptides (TetraF2W) obtained by converting the four phenylalanines in temporin-SHf to tryptophans. The temporin-SHf template was identified from the antimicrobial peptide database (http://aps.unmc.edu/AP). Remarkably, the double arginine variant (TetraF2W-RR) was more effective in killing methicillin-resistant Staphylococcus aureus (MRSA) USA300, but less cytotoxic to human skin HaCat and kidney HEK293 cells, than the lysine-containing dibasic combinations (KR, RK and KK). Killing kinetics and fluorescence spectroscopy suggest membrane targeting of TetraF2W-RR, making it more difficult for bacteria to develop resistance. Because established biofilms on medical devices are difficult to remove, we chose to covalently immobilize TetraF2W-RR onto the polyethylene terephthalate (PET) surface to prevent biofilm formation. The successful surface coating of the peptide is supported by FT-IR and XPS spectroscopies, chemical quantification, and antibacterial assays. This peptide-coated surface indeed prevented S. aureus biofilm formation with no cytotoxicity to human cells. In conclusion, TetraF2W-RR is a short Trp-rich peptide with demonstrated antimicrobial and anti-biofilm potency against MRSA in both the free and immobilized forms. Because these short peptides can be synthesized cost effectively, they may be developed into new antimicrobial agents or used as surface coating compounds.

  17. Durability-Based Design Guide for an Automotive Structural Composite: Part 2. Background Data and Models

    Energy Technology Data Exchange (ETDEWEB)

    Corum, J.M. [ORNL; Battiste, R.L. [ORNL; Brinkman, C.R. [ORNL; Ren, W. [ORNL; Ruggles, M.B. [ORNL; Weitsman, Y.J. [ORNL; Yahr, G.T. [ORNL

    1998-02-01

    This background report is a companion to the document entitled ''Durability-Based Design Criteria for an Automotive Structural Composite: Part 1. Design Rules'' (ORNL-6930). The rules and the supporting material characterization and modeling efforts described here are the result of a U.S. Department of Energy Advanced Automotive Materials project entitled ''Durability of Lightweight Composite Structures.'' The overall goal of the project is to develop experimentally based, durability-driven design guidelines for automotive structural composites. The project is closely coordinated with the Automotive Composites Consortium (ACC). The initial reference material addressed by the rules and this background report was chosen and supplied by ACC. The material is a structural reaction injection-molded isocyanurate (urethane), reinforced with continuous-strand, swirl-mat, E-glass fibers. This report consists of 16 position papers, each summarizing the observations and results of a key area of investigation carried out to provide the basis for the durability-based design guide. The durability issues addressed include the effects of cyclic and sustained loadings, temperature, automotive fluids, vibrations, and low-energy impacts (e.g., tool drops and roadway kickups) on deformation, strength, and stiffness. The position papers cover these durability issues. Topics include (1) tensile, compressive, shear, and flexural properties; (2) creep and creep rupture; (3) cyclic fatigue; (4) the effects of temperature, environment, and prior loadings; (5) a multiaxial strength criterion; (6) impact damage and damage tolerance design; (7) stress concentrations; (8) a damage-based predictive model for time-dependent deformations; (9) confirmatory subscale component tests; and (10) damage development and growth observations.

  18. A Guide RNA Sequence Design Platform for the CRISPR/Cas9 System for Model Organism Genomes

    Directory of Open Access Journals (Sweden)

    Ming Ma

    2013-01-01

    Full Text Available Cas9/CRISPR has been reported to efficiently induce targeted gene disruption and homologous recombination in both prokaryotic and eukaryotic cells. Thus, we developed a Guide RNA Sequence Design Platform for the Cas9/CRISPR silencing system for model organisms. The platform is easy to use for gRNA design with input query sequences. It finds potential targets by PAM and ranks them according to factors including uniqueness, SNP, RNA secondary structure, and AT content. The platform allows users to upload and share their experimental results. In addition, most guide RNA sequences from published papers have been put into our database.

  19. System design description for surface moisture measurement system (SMMS)

    Energy Technology Data Exchange (ETDEWEB)

    Vargo, G.F.

    1996-09-23

    The SMMS has been developed to measure moisture in the top few centimeters of tank waste. The SMMS development was initiated by the preliminary findings of SAR-033, and does not necessarily fulfill any established DQO. After the SAR-033 is released, if no significant changes are made, moisture measurements in the organic waste tanks will rapidly become a DQO. The SMMS was designed to be installed in any 4 inch or larger riser, and to allow maximum adjustability for riser lengths, and is used to deploy a sensor package on the waste surface within a 6 foot radius about the azimuth. The first sensor package will be a neutron probe.

  20. Adaptive optical design in surface plasma resonance sensor

    Institute of Scientific and Technical Information of China (English)

    ZHANG Feng; ZHONG Jin-gang

    2006-01-01

    A double-prism adaptive optical design in surface plasma resonance (SPR) sensor is proposed,which consists of two identical isosceles right-triangular prisms. One prism is used as a component of Kretschmann configuration,and the other is for regulation of the optical path. When double-prism structure is angle-scanned by an immovable incident ray,the output ray will be always parallel with the incident ray and just has a small displacement with the shift of output point.The output ray can be focused on a fixed photodetector by a convex lens.Thus it can be avoided that a prism and a photodetector rotate by θ and 2θ respectively in conventional angular scanning SPR sensor.This new design reduces the number of the movable components,makes the structure simple and compact,and makes the manipulation convenient.

  1. A DesignersGuide to Reliable Distributed Systems: Design and Analysis Methods. An Example Design. Volume 1

    Science.gov (United States)

    1988-08-01

    Additionally, SEND(m) and RECEIVE(m) primitives support internode communication to exchange their current views It is assumed that in this dictionary system, for...performance model is a multi-step process involving first a determination of the most relevant execution pathways in the system design (i.e., there are many...possible execution pathways in any system, and only a subset of those is used with great frequency). This shifts the focus upon those modules and the

  2. User's guide to designing and mounting lenses and mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Kowalskie, B.J.

    1978-02-17

    The guidebook is a practitioner-oriented supplement to standard texts in optics and mechanical engineering. It reflects practical experience with the oftentimes troublesome aspects of effectively integrating optical components with mechanical hardware. Accordingly, its focus is on the techniques, assumptions, and levels of design sophistication needed for a wide variety of sizes and optical surface quality levels. It is intended to be a primer for engineers, designers, and draftsmen already familiar with some of the problems encountered in mounting optical components and who are responsible for developing components for high-energy laser systems.

  3. Guiding Brain Tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-Held Raman Scanner

    OpenAIRE

    Karabeber, Hazem; Huang, Ruimin; Iacono, Pasquale; Samii, Jason M.; Pitter, Ken; Holland, Eric C.; Kircher, Moritz F.

    2014-01-01

    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-enhanced Raman scattering (SERS) nanoparticles, to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model. In a simulated intraoperative scenario, we tested both a static Raman imagi...

  4. Object-oriented design and programming with C++ your hands-on guide to C++ programming, with special emphasis on design, testing, and reuse

    CERN Document Server

    Leach, Ronald

    2014-01-01

    Object-Oriented Design and Programming with C++: Your Hands-On Guide to C++ Programming, with Special Emphasis on Design, Testing, and Reuse provides a list of software engineering principles to guide the software development process. This book presents the fundamentals of the C++ language.Organized into two parts encompassing 10 chapters, this book begins with an overview of C++ and describes object-oriented programming and the history of C++. This text then introduces classes, polymorphism, inheritance, and overloading. Other chapters consider the C++ preprocessor and organization of class l

  5. Progressive addition lens design by optimizing NURBS surface

    Science.gov (United States)

    Liu, Yen-Liang; Hsu, Wei-Yao; Cheng, Yuan-Chieh; Su, Guo-Dung

    2011-10-01

    Progressive addition lenses (PAL) are used to compensate presbyopia, which is induced by losing accommodation of elder eyes. These eyes need different optical power provided by eye glasses while watching objects at different distance. A smaller optical power is required in further distance and a larger one in nearer zone. A progressive addition lens can provides different power requirements in one piece of lens. This paper introduces a whole process of PAL production, from design, fabrication, to measurement. The PAL is designed by optimizing NURBS surface. Parameters of merit function are adjusted to design lenses with different specifications. The simulation results confirm that the power distributes as expected and cylinders are controlled under an acceptable level. Besides, sample lenses have been fabricated and measured. We apply precise-machining to produce the molds for plastic injection. Then, the samples are produced by injecting polycorbonate to the molds. Finally, Ultra Accuracy 3D Profilemeter is used to measure the sample PALs. Practical examinations shows that our designs are achievable and feasible in practice use.

  6. ICAM (Integrated Computer-Aided Manufacturing) Manufacturing Cost/Design Guide. Volume 7. Technology Transfer Summary.

    Science.gov (United States)

    1984-09-01

    advanced composite structures for production. Conduct material and manufacturing trade-off studies on ATF advanced design, NASA composite wing, and...255-7371. D-17 .* . . . . . . .. . .. .. . . . . . - . , o , . . - .’. TTD4502 60000 12 Sept 1984 CC tE % > LL 00 o0h K; Cr A .’ TTD450260000 12... coatings on the internal "Top-of-the-Line" Manu- observing the effect of the surfaces of hollowf~acturing Technology Success proposed change. Potential

  7. Computational design of surfaces, nanostructures and optoelectronic materials

    Science.gov (United States)

    Choudhary, Kamal

    Properties of engineering materials are generally influenced by defects such as point defects (vacancies, interstitials, substitutional defects), line defects (dislocations), planar defects (grain boundaries, free surfaces/nanostructures, interfaces, stacking faults) and volume defects (voids). Classical physics based molecular dynamics and quantum physics based density functional theory can be useful in designing materials with controlled defect properties. In this thesis, empirical potential based molecular dynamics was used to study the surface modification of polymers due to energetic polyatomic ion, thermodynamics and mechanics of metal-ceramic interfaces and nanostructures, while density functional theory was used to screen substituents in optoelectronic materials. Firstly, polyatomic ion-beams were deposited on polymer surfaces and the resulting chemical modifications of the surface were examined. In particular, S, SC and SH were deposited on amorphous polystyrene (PS), and C2H, CH3, and C3H5 were deposited on amorphous poly (methyl methacrylate) (PMMA) using molecular dynamics simulations with classical reactive empirical many-body (REBO) potentials. The objective of this work was to elucidate the mechanisms by which the polymer surface modification took place. The results of the work could be used in tailoring the incident energy and/or constituents of ion beam for obtaining a particular chemistry inside the polymer surface. Secondly, a new Al-O-N empirical potential was developed within the charge optimized many body (COMB) formalism. This potential was then used to examine the thermodynamic stability of interfaces and mechanical properties of nanostructures composed of aluminum, its oxide and its nitride. The potentials were tested for these materials based on surface energies, defect energies, bulk phase stability, the mechanical properties of the most stable bulk phase, its phonon properties as well as with a genetic algorithm based evolution theory of

  8. Parametric design of a part with free-form surfaces

    Institute of Scientific and Technical Information of China (English)

    KIM Yeoung-il; KIM Li-ra; JUN Cha-soo

    2006-01-01

    3D solid models for parts with regular-form surfaces (PRFSs) are effectively generated using traditional parametric design techniques. A new model is obtained by changing some parameters defining the model. The parts with free-form surfaces(PFFSs), however, cannot be defined by several parameters. Usually they are defined by some geometric elements like profile curves. The traditional parametric design approaches have not easily dealt with the PFFSs. A method for generating a solid model and an engineering drawing for PFFSs is proposed in this paper: First, the new profiles are generated from input point data. Second,the profile information is extracted from the existing model. Last, the old profiles are replaced with the new profiles. This method can preserve the associative information of the existing model and automatically generate the drawing including views, dimensions, and annotations. The proposed method has been implemented using a commercial CAD/CAM system, Unigraphics, and API functions written in C-language, and were applied to the blades of a turbine generator. Some illustrative examples are provided in order to show the effectiveness of the proposed method.

  9. Designing an artificial Lieb lattice on a metal surface

    Science.gov (United States)

    Qiu, Wen-Xuan; Li, Shuai; Gao, Jin-Hua; Zhou, Yi; Zhang, Fu-Chun

    2016-12-01

    Recently, several experiments [K. K. Gomes et al., Nature (London) 483, 306 (2012), 10.1038/nature10941; S. Wang et al., Phys. Rev. Lett. 113, 196803 (2014), 10.1103/PhysRevLett.113.196803] have illustrated that metal surface electrons can be manipulated to form a two-dimensional (2D) lattice by depositing a designer molecule lattice on a metal surface. This offers a promising new technique to construct artificial 2D electron lattices. Here we theoretically propose a molecule lattice pattern to realize an artificial Lieb lattice on a metal surface, which shows a flat electronic band due to the lattice geometry. We show that the localization of electrons in the flat band may be understood from the viewpoint of electron interference, which may be probed by measuring the local density of states with scanning tunneling microscopy. Our proposal may be readily implemented in experiment and may offer an ideal solid state platform to investigate the novel flat band physics of the Lieb lattice.

  10. WE-D-BRD-01: New Linac Designs for MR-Guided Therapy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Baillie, D.

    2015-06-15

    The advantages that make MR highly desirable for in-room treatment guidance, i.e. soft-tissue visualization and physiological assessment of healthy/tumor tissues, are largely recognized in the research community. However, the MR absorption in practical clinical workflows is still hindered by lack of sufficient technological infrastructure. Recent advances have been made towards filling that gap such as the development of integrated therapy systems relying on an MR scanner and a radiation source (linac, Co-60) and/or brachytherapy. The session is intended to present new efforts and methods aimed at facilitating the adoption of MR guidance for treatment delivery. Specifically, the discussion will focus on a) linac designs for reduced footprint and seamless integration with MR/linac systems, b) tracking coils for brachytherapy applications, and c) procedures for the commissioning and monitoring of MR and MR/linac performance. Learning Objectives: Understand limitations and proposed solutions for linac designs and associated integration with MR/linac systems; Understand current issues with MR-guided brachytherapy procedures Understand the issues and needs for new MR commissioning and QC. License agreement with Modus Medical Devices to develop a phantom for the quantification of MR image distortions.

  11. Structure-guided inhibitor design for human FAAH by interspecies active site conversion

    Energy Technology Data Exchange (ETDEWEB)

    Mileni, Mauro; Johnson, Douglas S.; Wang, Zhigang; Everdeen, Daniel S.; Liimatta, Marya; Pabst, Brandon; Bhattacharya, Keshab; Nugent, Richard A.; Kamtekar, Satwik; Cravatt, Benjamin F.; Ahn, Kay; Stevens, Raymond C. (Scripps); (Pfizer)

    2008-11-24

    The integral membrane enzyme fatty acid amide hydrolase (FAAH) hydrolyzes the endocannabinoid anandamide and related amidated signaling lipids. Genetic or pharmacological inactivation of FAAH produces analgesic, anxiolytic, and antiinflammatory phenotypes but not the undesirable side effects of direct cannabinoid receptor agonists, indicating that FAAH may be a promising therapeutic target. Structure-based inhibitor design has, however, been hampered by difficulties in expressing the human FAAH enzyme. Here, we address this problem by interconverting the active sites of rat and human FAAH using site-directed mutagenesis. The resulting humanized rat (h/r) FAAH protein exhibits the inhibitor sensitivity profiles of human FAAH but maintains the high-expression yield of the rat enzyme. We report a 2.75-{angstrom} crystal structure of h/rFAAH complexed with an inhibitor, N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide (PF-750), that shows strong preference for human FAAH. This structure offers compelling insights to explain the species selectivity of FAAH inhibitors, which should guide future drug design programs.

  12. A "How-To" Guide for Designing Judgment Bias Studies to Assess Captive Animal Welfare.

    Science.gov (United States)

    Bethell, Emily J

    2015-01-01

    Robust methods to assess nonhuman animal emotion are essential for ensuring good welfare in captivity. Cognitive bias measures such as the judgment bias task have recently emerged as promising tools to assess animal emotion. The simple design and objective response measures make judgment bias tasks suitable for use across species and contexts. In reviewing 64 studies published to date, it emerged that (a) judgment biases have been measured in a number of mammals and birds and an invertebrate; (b) no study has tested judgment bias in any species of fish, amphibian, or reptile; and (c) no study has yet investigated judgment bias in a zoo or aquarium. This article proposes that judgment bias measures are highly suitable for use with these understudied taxa and can provide new insight into welfare in endangered species housed in zoos and aquariums, where poor welfare impacts breeding success and, ultimately, species survival. The article includes a "how-to" guide to designing judgment bias tests with recommendations for working with currently neglected "exotics" including fishes, amphibians, and reptiles.

  13. Iterative experiment design guides the characterization of a light-inducible gene expression circuit.

    Science.gov (United States)

    Ruess, Jakob; Parise, Francesca; Milias-Argeitis, Andreas; Khammash, Mustafa; Lygeros, John

    2015-06-30

    Systems biology rests on the idea that biological complexity can be better unraveled through the interplay of modeling and experimentation. However, the success of this approach depends critically on the informativeness of the chosen experiments, which is usually unknown a priori. Here, we propose a systematic scheme based on iterations of optimal experiment design, flow cytometry experiments, and Bayesian parameter inference to guide the discovery process in the case of stochastic biochemical reaction networks. To illustrate the benefit of our methodology, we apply it to the characterization of an engineered light-inducible gene expression circuit in yeast and compare the performance of the resulting model with models identified from nonoptimal experiments. In particular, we compare the parameter posterior distributions and the precision to which the outcome of future experiments can be predicted. Moreover, we illustrate how the identified stochastic model can be used to determine light induction patterns that make either the average amount of protein or the variability in a population of cells follow a desired profile. Our results show that optimal experiment design allows one to derive models that are accurate enough to precisely predict and regulate the protein expression in heterogeneous cell populations over extended periods of time.

  14. Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

    Science.gov (United States)

    Ferry, Quentin R. V.; Lyutova, Radostina; Fulga, Tudor A.

    2017-01-01

    CRISPR-based transcription regulators (CRISPR-TRs) have transformed the current synthetic biology landscape by allowing specific activation or repression of any target gene. Here we report a modular and versatile framework enabling rapid implementation of inducible CRISPR-TRs in mammalian cells. This strategy relies on the design of a spacer-blocking hairpin (SBH) structure at the 5′ end of the single guide RNA (sgRNA), which abrogates the function of CRISPR-transcriptional activators. By replacing the SBH loop with ligand-controlled RNA-cleaving units, we demonstrate conditional activation of quiescent sgRNAs programmed to respond to genetically encoded or externally delivered triggers. We use this system to couple multiple synthetic and endogenous target genes with specific inducers, and assemble gene regulatory modules demonstrating parallel and orthogonal transcriptional programs. We anticipate that this ‘plug and play' approach will be a valuable addition to the synthetic biology toolkit, facilitating the understanding of natural gene circuits and the design of cell-based therapeutic strategies. PMID:28256578

  15. Guide to good practices for the design, development, and implementation of examinations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The purpose of this Guide to Good Practices is to provide direction to training personnel in the broad areas of design, development, and implementation of examinations. Nuclear facilities spend a significant amount of training resources testing trainees. Tests are used for employee selection, qualification, requalification, certification and recertification, and promotion. Ineffective testing procedures, or inappropriate interpretation of test results, can have significant effects on both human performance and facility operations. Test development requires unique skills, and as with any skill, training and experience are needed to develop the skills. Test development, test use, test result interpretation, and test refinement, like all other aspects of the systematic approach to training, should be part of an ongoing, systematic process. For some users this document will provide a review of ideas and principles with which they are already familiar; for others it will present new concepts. While not intended to provide in-depth coverage of test theory design and development, it should provide developers, instructors, and evaluators with a foundation on which to develop sound examinations.

  16. Transition-state-guided drug design for treatment of parasitic neglected tropical diseases.

    Science.gov (United States)

    Murkin, A S; Moynihan, M M

    2014-01-01

    Many of the deadliest neglected tropical diseases are caused by protozoan and helminthic parasites. These organisms have evolved several enzymes to exploit their host's metabolic resources and evade immune responses. Because these essential proteins are absent in humans, they are targets for antiparasitic drug development. Despite decades of investigation, no therapy has been successful in the eradication of these diseases, so new approaches are desired. Chemically stable analogues of the transition states of enzymatic reactions are often potent inhibitors, and several examples of clinically effective compounds are known for other diseases. The design of transition-state analogues is aided by structural models of the transition state, which are obtained by complementing experimental measurement of kinetic isotope effects with theoretical calculations. Such transition-state-guided inhibitor design has been demonstrated for human, bovine, malarial, and trypanosomal enzymes of the purine salvage pathway, including purine nucleoside phosphorylase, nucleoside hydrolases, and adenosine deaminase. Cysteine proteases, trans-sialidase, 1-deoxy-d-xylulose-5-phosphate reductoisomerase, and trypanothione synthetase are presented as additional candidates for application of transition-state analysis with the goal of identifying new leads for the treatment of parasitic neglected tropical diseases.

  17. Design of a Remote-controlled and GPS-guided Autonomous Robot for Precision Farming

    Directory of Open Access Journals (Sweden)

    İlker Ünal

    2015-12-01

    Full Text Available Determining variations in fields is important for precision farming applications. Precision farming is used to determine, analyse, and manage factors such as temporal and spatial variability to obtain maximum profit, sustainability, and environmental protection. However, precision farming is excessively dependent on soil and plant test processes. Furthermore, test processes are time-consuming, laborious and expensive. These processes also cannot be performed quickly by humans. For these reasons, autonomous robots should be designed and developed for the detection of field variations and variable-rate applications. In this study, a remote-controlled and GPS-guided autonomous robot was designed and developed, which can be controlled via the 3G internet and is suitable for image-processing applications. The joystick is used to manually remotely control the robot movements in any direction or speed. Real-time video transmission to the remote computer can be accomplished with a camera placed on the vehicle. Navigation software was developed for steering the robot autonomously. In the results of the field test for the navigation software, it was found that the linear target point precision ranged from 10 to 12 cm and the distributed target point precision ranged from 15 to 17 cm.

  18. Technical Support Document: The Development of the Advanced Energy Design Guide for Small Warehouse and Self-Storage Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Bing; Jarnagin, Ronald E.; Jiang, Wei; Gowri, Krishnan

    2007-12-01

    This Technical Support Document (TSD) describes the process and methodology for development of the Advanced Energy Design Guide for Small Warehouse and Self-storage Buildings (AEDG-WH or the Guide), a design guidance document intended to provide recommendations for achieving 30% energy savings in small warehouses over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The AEDG-WH is the fourth in a series of guides being developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc. (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA), the United States Green Buildings Council (USGBC), and the U.S. Department of Energy (DOE).

  19. Enhanced Photocatalytic Activity of Bismuth Precursor by Rapid Phase and Surface Transformation Using Structure-Guided Combustion Waves.

    Science.gov (United States)

    Lee, Kang Yeol; Hwang, Hayoung; Kim, Tae Ho; Choi, Wonjoon

    2016-02-10

    The development of an efficient method for manipulating phase and surface transformations would facilitate the improvement of catalytic materials for use in a diverse range of applications. Herein, we present the first instance of a submicrosecond time frame direct phase and surface transformation of Bi(NO3)3 rods to nanoporous β-Bi2O3 rods via structure-guided combustion waves. Hybrid composites of the prepared Bi(NO3)3·H2O rods and organic fuel were fabricated by a facile preparation method. The anisotropic propagation of combustion waves along the interfacial boundaries of Bi(NO3)3·H2O rods induced direct phase transformation to β-Bi2O3 rods in the original structure due to the rapid pyrolysis, while the release of gas molecules enabled the formation of nanoporous structures on the surfaces of rods. The developed β-Bi2O3 rods showed improved photocatalytic activity for the photodegradation of rhodamine B in comparison with Bi(NO3)3·H2O rods and α-Bi2O3 rods due to the more suitable interdistance and the large contact areas of the porous surfaces. This new method of using structure-guided combustion waves for phase and surface transformation may contribute to the development of new catalysts as well as the precise manipulation of diverse micronanostructured materials.

  20. DISTRIBUTED EXTERNAL SURFACE HARDENING OF CAR DESIGN BY WINDING

    Directory of Open Access Journals (Sweden)

    O. V. Fomin

    2017-04-01

    Full Text Available Purpose. The paper involves coverage of features and results of the research conducted by the authors to determine the feasibility and establishment of pre-stressed-strained state of freight cars by winding in order to improve their strength characteristics. It is also necessary to present the theoretical justification for the effectiveness of the application of this method for car designs and an appropriate example for the tank-car. Methodology. The conducted study is based on an analysis of known works on the subject, mathematical justification and computer modeling. At the calculations of rolling stock components contemporary conventional techniques were used. Findings. Authors found that the winding method for pre-stressed-strained state is effective and appropriate for use in the construction of railway rolling stock and, in particular freight cars. Freight car designs with the pre-stressed-strained state are characterized by a number of strength advantages, among which there is an improvement of the work on the perception of operational loads and resource conservation. Originality. For the first time it is proposed the improvement of bearing capacity of freight car constructions through the creation of its component in the directed stress-strained state. It is also for the first time proposed the use of distributed external surface hardening by the method of winding to create a pre-stress-strained state of structural components of freight cars. The methods for winding designs of freight cars and their implementation were considered. Practical value. The studies developed a number of technical solutions for improving the design of freight cars and tank-container, which has been patented. Corresponding solutions for the tank-car are partially presented. Practical implementation of such solutions will significantly improve the technical, economic and operational performances of car designs.

  1. Reducing Design Risk Using Robust Design Methods: A Dual Response Surface Approach

    Science.gov (United States)

    Unal, Resit; Yeniay, Ozgur; Lepsch, Roger A. (Technical Monitor)

    2003-01-01

    Space transportation system conceptual design is a multidisciplinary process containing considerable element of risk. Risk here is defined as the variability in the estimated (output) performance characteristic of interest resulting from the uncertainties in the values of several disciplinary design and/or operational parameters. Uncertainties from one discipline (and/or subsystem) may propagate to another, through linking parameters and the final system output may have a significant accumulation of risk. This variability can result in significant deviations from the expected performance. Therefore, an estimate of variability (which is called design risk in this study) together with the expected performance characteristic value (e.g. mean empty weight) is necessary for multidisciplinary optimization for a robust design. Robust design in this study is defined as a solution that minimizes variability subject to a constraint on mean performance characteristics. Even though multidisciplinary design optimization has gained wide attention and applications, the treatment of uncertainties to quantify and analyze design risk has received little attention. This research effort explores the dual response surface approach to quantify variability (risk) in critical performance characteristics (such as weight) during conceptual design.

  2. CAD/CAM (Computer Aided Design/Computer Aided Manufacture). A Brief Guide to Materials in the Library of Congress.

    Science.gov (United States)

    Havas, George D.

    This brief guide to materials in the Library of Congress (LC) on computer aided design and/or computer aided manufacturing lists reference materials and other information sources under 13 headings: (1) brief introductions; (2) LC subject headings used for such materials; (3) textbooks; (4) additional titles; (5) glossaries and handbooks; (6)…

  3. Indoor Air Quality (IAQ) Schools and Universities: Overview of Indoor Air Quality Issues, and Preliminary Design Guide.

    Science.gov (United States)

    Healthy Buildings International, Inc., Fairfax, VA.

    This guide is intended to help the building design, engineering, and maintenance staff of school buildings maintain a common standard of high indoor air quality (IAQ) and a productive and comfortable workplace for students and staff. The report defines the four basic classifications of indoor environmental pollution, lists the factors impacting…

  4. Legionellosis prevention in building water and HVAC systems a practical guide for design, operation and maintenance to minimize the risk

    CERN Document Server

    Joppolo, Cesare Maria; Pitera, Luca Alberto; Angermann, Jean Pierre; Izard, Mark

    2013-01-01

    This Guidebook is a practical guide for design, operation and maintenance to minimize the risk of legionellosis in building water and HVAC systmes. It is devided into several themes such as: Air conditioning of the air (by water – humidification), Production of hot water for washing (fundamentally but not only hot water for washing) and Evaporative cooling tower.

  5. Structure-guided fragment-based in silico drug design of dengue protease inhibitors.

    Science.gov (United States)

    Knehans, Tim; Schüller, Andreas; Doan, Danny N; Nacro, Kassoum; Hill, Jeffrey; Güntert, Peter; Madhusudhan, M S; Weil, Tanja; Vasudevan, Subhash G

    2011-03-01

    An in silico fragment-based drug design approach was devised and applied towards the identification of small molecule inhibitors of the dengue virus (DENV) NS2B-NS3 protease. Currently, no DENV protease co-crystal structure with bound inhibitor and fully formed substrate binding site is available. Therefore a homology model of DENV NS2B-NS3 protease was generated employing a multiple template spatial restraints method and used for structure-based design. A library of molecular fragments was derived from the ZINC screening database with help of the retrosynthetic combinatorial analysis procedure (RECAP). 150,000 molecular fragments were docked to the DENV protease homology model and the docking poses were rescored using a target-specific scoring function. High scoring fragments were assembled to small molecule candidates by an implicit linking cascade. The cascade included substructure searching and structural filters focusing on interactions with the S1 and S2 pockets of the protease. The chemical space adjacent to the promising candidates was further explored by neighborhood searching. A total of 23 compounds were tested experimentally and two compounds were discovered to inhibit dengue protease (IC(50) = 7.7 μM and 37.9 μM, respectively) and the related West Nile virus protease (IC(50) = 6.3 μM and 39.0 μM, respectively). This study demonstrates the successful application of a structure-guided fragment-based in silico drug design approach for dengue protease inhibitors providing straightforward hit generation using a combination of homology modeling, fragment docking, chemical similarity and structural filters.

  6. From loquacious to reticent: understanding patient health information communication to guide consumer health IT design.

    Science.gov (United States)

    Valdez, Rupa S; Guterbock, Thomas M; Fitzgibbon, Kara; Williams, Ishan C; Wellbeloved-Stone, Claire A; Bears, Jaime E; Menefee, Hannah K

    2017-07-01

    It is increasingly recognized that some patients self-manage in the context of social networks rather than alone. Consumer health information technology (IT) designed to support socially embedded self-management must be responsive to patients' everyday communication practices. There is an opportunity to improve consumer health IT design by explicating how patients currently leverage social media to support health information communication. The objective of this study was to determine types of health information communication patterns that typify Facebook users with chronic health conditions to guide consumer health IT design. Seven hundred participants with type 2 diabetes were recruited through a commercial survey access panel. Cluster analysis was used to identify distinct approaches to health information communication both on and off Facebook. Analysis of variance (ANOVA) methods were used to identify demographic and behavioral differences among profiles. Secondary analysis of qualitative interviews ( n  = 25) and analysis of open-ended survey questions were conducted to understand participant rationales for each profile. Our analysis yielded 7 distinct health information communication profiles. Five of 7 profiles had consistent patterns both on and off Facebook, while the remaining 2 demonstrated distinct practices, with no health information communication on Facebook but some off Facebook. One profile was distinct from all others in both health information communication practices and demographic composition. Rationales for following specific health information communication practices were categorized under 6 themes: altruism, instrumental support, social support, privacy and stigma, convenience, and Facebook knowledge. Facebook has been widely adopted for health information communication; This study demonstrates that Facebook has been widely adopted for health information communication. It also shows that the ways in which patients communicate health

  7. Energy-conscious design of newly built houses. Basic guide. 2. ed.; Energiebewust ontwerpen van nieuwbouwwoningen. Vademecum

    Energy Technology Data Exchange (ETDEWEB)

    Stofberg, F.; Israels, E. [BOOM, Milieukundig Onderzoek- en OntwerpBuro, Delft/Maastricht (Netherlands); Gommans, L. [Faculteit Bouwkunde, Technische Universiteit Delft, Delft (Netherlands)

    2000-02-01

    This basic guide is a richly illustrated vade mecum with answers to questions related to the energy efficient design of housing projects. Attention is paid to building engineering and installation engineering aspects. Among other things it comprises a checklist for energy-conscious design, an elaborated list of keywords, and the energy saving measures from the National Package for House Construction ('Nationaal Pakket Woningbouw')

  8. Collimator design for a dedicated molecular breast imaging-guided biopsy system: Proof-of-concept

    Energy Technology Data Exchange (ETDEWEB)

    Weinmann, Amanda L.; Hruska, Carrie B.; Conners, Amy L.; O' Connor, Michael K. [Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905 (United States)

    2013-01-15

    Purpose: Molecular breast imaging (MBI) is a dedicated nuclear medicine breast imaging modality that employs dual-head cadmium zinc telluride (CZT) gamma cameras to functionally detect breast cancer. MBI has been shown to detect breast cancers otherwise occult on mammography and ultrasound. Currently, a MBI-guided biopsy system does not exist to biopsy such lesions. Our objective was to consider the utility of a novel conical slant-hole (CSH) collimator for rapid (<1 min) and accurate monitoring of lesion position to serve as part of a MBI-guided biopsy system. Methods: An initial CSH collimator design was derived from the dimensions of a parallel-hole collimator optimized for MBI performed with dual-head CZT gamma cameras. The parameters of the CSH collimator included the collimator height, cone slant angle, thickness of septa and cones of the collimator, and the annular areas exposed at the base of the cones. These parameters were varied within the geometric constraints of the MBI system to create several potential CSH collimator designs. The CSH collimator designs were evaluated using Monte Carlo simulations. The model included a breast compressed to a thickness of 6 cm with a 1-cm diameter lesion located 3 cm from the collimator face. The number of particles simulated was chosen to represent the count density of a low-dose, screening MBI study acquired with the parallel-hole collimator for 10 min after a {approx}150 MBq (4 mCi) injection of Tc-99m sestamibi. The same number of particles was used for the CSH collimator simulations. In the resulting simulated images, the count sensitivity, spatial resolution, and accuracy of the lesion depth determined from the lesion profile width were evaluated. Results: The CSH collimator design with default parameters derived from the optimal parallel-hole collimator provided 1-min images with error in the lesion depth estimation of 1.1 {+-} 0.7 mm and over 21 times the lesion count sensitivity relative to 1-min images

  9. Designing high-temperature steels via surface science and thermodynamics

    Science.gov (United States)

    Gross, Cameron T.; Jiang, Zilin; Mathai, Allan; Chung, Yip-Wah

    2016-06-01

    Electricity in many countries such as the US and China is produced by burning fossil fuels in steam-turbine-driven power plants. The efficiency of these power plants can be improved by increasing the operating temperature of the steam generator. In this work, we adopted a combined surface science and computational thermodynamics approach to the design of high-temperature, corrosion-resistant steels for this application. The result is a low-carbon ferritic steel with nanosized transition metal monocarbide precipitates that are thermally stable, as verified by atom probe tomography. High-temperature Vickers hardness measurements demonstrated that these steels maintain their strength for extended periods at 700 °C. We hypothesize that the improved strength of these steels is derived from the semi-coherent interfaces of these thermally stable, nanosized precipitates exerting drag forces on impinging dislocations, thus maintaining strength at elevated temperatures.

  10. Probing topological protection using a designer surface plasmon structure

    Science.gov (United States)

    Gao, Fei; Gao, Zhen; Shi, Xihang; Yang, Zhaoju; Lin, Xiao; Xu, Hongyi; Joannopoulos, John D.; Soljačić, Marin; Chen, Hongsheng; Lu, Ling; Chong, Yidong; Zhang, Baile

    2016-01-01

    Topological photonic states, inspired by robust chiral edge states in topological insulators, have recently been demonstrated in a few photonic systems, including an array of coupled on-chip ring resonators at communication wavelengths. However, the intrinsic difference between electrons and photons determines that the ‘topological protection' in time-reversal-invariant photonic systems does not share the same robustness as its counterpart in electronic topological insulators. Here in a designer surface plasmon platform consisting of tunable metallic sub-wavelength structures, we construct photonic topological edge states and probe their robustness against a variety of defect classes, including some common time-reversal-invariant photonic defects that can break the topological protection, but do not exist in electronic topological insulators. This is also an experimental realization of anomalous Floquet topological edge states, whose topological phase cannot be predicted by the usual Chern number topological invariants. PMID:27197877

  11. Array projector design for projection on arbitrarily curved surfaces

    Science.gov (United States)

    Fischer, Stephanie; Schreiber, Peter; Riedel, Alf; Sieler, Marcel

    2015-09-01

    The micro-optical array projector is a new and innovative possibility to project patterns onto arbitrary shaped surfaces1 . In contrast to single-aperture systems the illuminance of the projected image is raised by only increasing the lateral extent of the projector while keeping the length constant. Thanks to the setup - analogous to a fly's eye condenser - we obtain a very compact design with homogenization of illumination. The images to be projected are presented as arbitrarily curved CAD-objects. Because of its complexity, the first attempt was a chief-ray backtrace implemented into a CAD-program, with the individual projectorlets modelled as pinhole cameras. With this principle one can trace the slides for several applications like the projection on perpendicular, as well as tilted and curved surfaces. Since aberrations cannot be considered with the simple CAD backtrace described above, we used the commercially available raytracer Zemax®, controlled by a macro, working in conjunction with a CADprogram for improved slide mask generation. Despite both methods, depending on the complexity of the optical system, are generating the fundamental mask data, the paper will show that there is a tradeoff between calculation time and accuracy. Based on this evaluation we will discuss further development as well as the possibility of improvement concerning the calculation methods. The different methods were investigated to determine their advantages and disadvantages. This provides the basis for the scope of application. Further we will demonstrate simulations as well as results obtained with built demonstrators.

  12. Experimental Design on Laminated Veneer Lumber Fiber Composite: Surface Enhancement

    Science.gov (United States)

    Meekum, U.; Mingmongkol, Y.

    2010-06-01

    Thick laminate veneer lumber(LVL) fibre reinforced composites were constructed from the alternated perpendicularly arrayed of peeled rubber woods. Glass woven was laid in between the layers. Native golden teak veneers were used as faces. In house formulae epoxy was employed as wood adhesive. The hand lay-up laminate was cured at 150° C for 45 mins. The cut specimen was post cured at 80° C for at least 5 hours. The 2k factorial design of experimental(DOE) was used to verify the parameters. Three parameters by mean of silane content in epoxy formulation(A), smoke treatment of rubber wood surface(B) and anti-termite application(C) on the wood surface were analysed. Both low and high levels were further subcategorised into 2 sub-levels. Flexural properties were the main respond obtained. ANOVA analysis of the Pareto chart was engaged. The main effect plot was also testified. The results showed that the interaction between silane quantity and termite treatment is negative effect at high level(AC+). Vice versa, the interaction between silane and smoke treatment was positive significant effect at high level(AB+). According to this research work, the optimal setting to improve the surface adhesion and hence flexural properties enhancement were high level of silane quantity, 15% by weight, high level of smoked wood layers, 8 out of 14 layers, and low anti termite applied wood. The further testes also revealed that the LVL composite had superior properties that the solid woods but slightly inferior in flexibility. The screw withdrawn strength of LVL showed the higher figure than solid wood. It is also better resistance to moisture and termite attack than the rubber wood.

  13. Design of the wavefront sensor unit of ARGOS, the LBT laser guide star system

    CERN Document Server

    Bonaglia, Marco

    2012-01-01

    ARGOS is the laser guide star ground layer adaptive optics system of the LBT. ARGOS is designed to bring a moderate but uniform reduction of the PSF size over a FoV as large as 4x4arcmin, allowing a significative increase of the science throughput of LUCI, the LBT NIR imager and MOS. ARGOS relays on 3 Rayleigh beacons to sense the lower layers of the atmosphere achieving almost 100% sky coverage. The ground layer AO correction is allowed by the 2 adaptive secondaries of the LBT. This PhD thesis first discusses a study based on numerical simulations and aimed to evaluate the performance of ARGOS. This work has been carried out using CAOS and representing in the code most of the features that characterize the system itself: as the laser beacon propagation in the atmosphere, the SH type wavefront sensing, the AO reconstruction and closed loop delays and the atmosphere tip-tilt sensing done using a NGS and a quad-cell type sensor. The results obtained in this study are in agreement and definitively confirm the pe...

  14. Structure guided design of biotin protein ligase inhibitors for antibiotic discovery.

    Science.gov (United States)

    Paparella, Ashleigh S; Soares da Costa, Tatiana P; Yap, Min Y; Tieu, William; Wilce, Matthew C J; Booker, Grant W; Abell, Andrew D; Polyak, Steven W

    2014-01-01

    Biotin protein ligase (BPL) represents a promising target for the discovery of new antibacterial chemotherapeutics. Here we review the central role of BPL for the survival and virulence of clinically important Staphylococcus aureus in support of this claim. X-ray crystallography structures of BPLs in complex with ligands and small molecule inhibitors provide new insights into the mechanism of protein biotinylation, and a template for structure guided approaches to the design of inhibitors for antibacterial discovery. Most BPLs employ an ordered ligand binding mechanism for the synthesis of the reaction intermediate biotinyl-5´-AMP from substrates biotin and ATP. Recent studies reporting chemical analogs of biotin and biotinyl-5´-AMP as BPL inhibitors that represent new classes of anti-S. aureus agents are reviewed. We highlight strategies to selectively inhibit bacterial BPL over the mammalian equivalent using a 1,2,3-triazole isostere to replace the labile phosphoanhydride naturally present in biotinyl-5´-AMP. A novel in situ approach to improve the detection of triazole-based inhibitors is also presented that could potentially be widely applied to other protein targets.

  15. Optical flow based guidance system design for semi-strapdown image homing guided missiles

    Directory of Open Access Journals (Sweden)

    Huang Lan

    2016-10-01

    Full Text Available This paper focuses mainly on semi-strapdown image homing guided (SSIHG system design based on optical flow for a six-degree-of-freedom (6-DOF axial-symmetric skid-to-turn missile. Three optical flow algorithms suitable for large displacements are introduced and compared. The influence of different displacements on computational accuracy of the three algorithms is analyzed statistically. The total optical flow of the SSIHG missile is obtained using the Scale Invariant Feature Transform (SIFT algorithm, which is the best among the three for large displacements. After removing the rotational optical flow caused by rotation of the gimbal and missile body from the total optical flow, the remaining translational optical flow is smoothed via Kalman filtering. The circular navigation guidance (CNG law with impact angle constraint is then obtained utilizing the smoothed translational optical flow and position of the target image. Simulations are carried out under both disturbed and undisturbed conditions, and results indicate the proposed guidance strategy for SSIHG missiles can result in a precise target hit with a desired impact angle without the need for the time-to-go parameter.

  16. Design optimization of large-size format edge-lit light guide units

    Science.gov (United States)

    Hastanin, J.; Lenaerts, C.; Fleury-Frenette, K.

    2016-04-01

    In this paper, we present an original method of dot pattern generation dedicated to large-size format light guide plate (LGP) design optimization, such as photo-bioreactors, the number of dots greatly exceeds the maximum allowable number of optical objects supported by most common ray-tracing software. In the proposed method, in order to simplify the computational problem, the original optical system is replaced by an equivalent one. Accordingly, an original dot pattern is splitted into multiple small sections, inside which the dot size variation is less than the ink dots printing typical resolution. Then, these sections are replaced by equivalent cells with continuous diffusing film. After that, we adjust the TIS (Total Integrated Scatter) two-dimensional distribution over the grid of equivalent cells, using an iterative optimization procedure. Finally, the obtained optimal TIS distribution is converted into the dot size distribution by applying an appropriate conversion rule. An original semi-empirical equation dedicated to rectangular large-size LGPs is proposed for the initial guess of TIS distribution. It allows significantly reduce the total time needed to dot pattern optimization.

  17. A Policymaker's Guide to Feed-in Tariff Policy Design

    Energy Technology Data Exchange (ETDEWEB)

    Couture, Toby D. [E3 Analytics, Berlin (Germany); Cory, Karlynn [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kreycik, Claire [National Renewable Energy Lab. (NREL), Golden, CO (United States); Williams, Emily [U.S. Dept. of Energy, Washington, DC (United States)

    2010-07-01

    Feed-in tariffs (FITs) are the most widely used renewable energy policy in the world for driving accelerating renewable energy (RE) deployment, accounting for a greater share of RE development than either tax incentives or renewable portfolio standard (RPS) policies. FITs have generated significant RE deployment, helping bring the countries that have implemented them successfully to the forefront of the global RE industry. In the European Union (EU), FIT policies have led to the deployment of more than 15,000 MW of solar photovoltaic (PV) power and more than 55,000 MW of wind power between 2000 and the end of 2009. In total, FITs are responsible for approximately 75% of global PV and 45% of global wind deployment. Countries such as Germany, in particular, have demonstrated that FITs can be used as a powerful policy tool to drive RE deployment and help meet combined energy security and emissions reductions objectives. This policymaker’s guide provides a detailed analysis of FIT policy design and implementation and identifies a set of best practices that have been effective at quickly stimulating the deployment of large amounts of RE generation.

  18. Policymaker's Guide to Feed-in Tariff Policy Design

    Energy Technology Data Exchange (ETDEWEB)

    Couture, T. D.; Cory, K.; Kreycik, C.; Williams, E.

    2010-07-01

    Feed-in tariffs (FITs) are the most widely used renewable energy policy in the world for driving accelerating renewable energy (RE) deployment, accounting for a greater share of RE development than either tax incentives or renewable portfolio standard (RPS) policies. FITs have generated significant RE deployment, helping bring the countries that have implemented them successfully to the forefront of the global RE industry. In the European Union (EU), FIT policies have led to the deployment of more than 15,000 MW of solar photovoltaic (PV) power and more than 55,000 MW of wind power between 2000 and the end of 2009. In total, FITs are responsible for approximately 75% of global PV and 45% of global wind deployment. Countries such as Germany, in particular, have demonstrated that FITs can be used as a powerful policy tool to drive RE deployment and help meet combined energy security and emissions reductions objectives. This policymaker's guide provides a detailed analysis of FIT policy design and implementation and identifies a set of best practices that have been effective at quickly stimulating the deployment of large amounts of RE generation. Although the discussion is aimed primarily at decision makers who have decided that a FIT policy best suits their needs, exploration of FIT policies can also help inform a choice among alternative renewable energy policies.

  19. Guiding principles for printed education materials: design preferences of people with aphasia.

    Science.gov (United States)

    Rose, Tanya A; Worrall, Linda E; Hickson, Louise M; Hoffmann, Tammy C

    2012-02-01

    The objectives of this study were to obtain the preferences of people with aphasia for the design of stroke and aphasia printed education materials (PEMs) and to compare these preferences with recommendations in the literature for developing written information for other populations. A face-to-face quantitative questionnaire was completed with 40 adults with aphasia post-stroke. The questionnaire explored preferences for: (1) the representation of numbers, (2) font size and type, (3) line spacing, (4) document length, and (5) graphic type. Most preferences (62.4%, n = 146) were for numbers expressed as figures rather than words. The largest proportion of participants selected 14 point (28.2%, n = 11) and Verdana ref (33.3%, n = 13) as the easiest font size and type to read, and a preference for 1.5 line spacing (41.0%, n = 16) was identified. Preference for document length was not related to the participant's reading ability or aphasia severity. Most participants (95.0%, n = 38) considered graphics to be helpful, with photographs more frequently reported as a helpful graphic type. The identified preferences support many of the formatting recommendations found within the literature. This research provides guiding principles for developing PEMs in preferred formats for people with aphasia.

  20. Retrievable surface storage facility conceptual system design description

    Energy Technology Data Exchange (ETDEWEB)

    1977-03-01

    The studies evaluated several potentially attractive methods for processing and retrievably storing high-level radioactive waste after delivery to the Federal repository. These studies indicated that several systems could be engineered to safely store the waste, but that the simplest and most attractive concept from a technical standpoint would be to store the waste in a sealed stainless steel canister enclosed in a 2 in. thick carbon steel cask which in turn would be inserted into a reinforced concrete gamma-neutron shield, which would also provide the necessary air-cooling through an air annulus between the cask and the shield. This concept best satisfies the requirements for safety, long-term exposure to natural phenomena, low capital and operating costs, retrievability, amenability to incremental development, and acceptably small environmental impact. This document assumes that the reference site would be on ERDA's Hanford reservation. This document is a Conceptual System Design Description of the facilities which could satisfy all of the functional requirements within the established basic design criteria. The Retrievable Surface Storage Facility (RSSF) is planned with the capacity to process and store the waste received in either a calcine or glass/ceramic form. The RSSF planning is based on a modular development program in which the modular increments are constructed at rates matching projected waste receipts.

  1. Measurements of shock-induced guided and surface acoustic waves along boreholes in poroelastic materials

    NARCIS (Netherlands)

    Chao, G.; Smeulders, D.M.J.; Van Dongen, M.E.H.

    2006-01-01

    Acoustic experiments on the propagation of guided waves along water-filled boreholes in water-saturated porous materials are reported. The experiments were conducted using a shock tube technique. An acoustic funnel structure was placed inside the tube just above the sample in order to enhance the ex

  2. Surface-Guided Core-Shell ZnSe@ZnTe Nanowires as Radial p-n Heterojunctions with Photovoltaic Behavior.

    Science.gov (United States)

    Oksenberg, Eitan; Martí-Sánchez, Sara; Popovitz-Biro, Ronit; Arbiol, Jordi; Joselevich, Ernesto

    2017-06-27

    The organization of nanowires on surfaces remains a major obstacle toward their large-scale integration into functional devices. Surface-material interactions have been used, with different materials and substrates, to guide horizontal nanowires during their growth into well-organized assemblies, but the only guided nanowire heterostructures reported so far are axial and not radial. Here, we demonstrate the guided growth of horizontal core-shell nanowires, specifically of ZnSe@ZnTe, with control over their crystal phase and crystallographic orientations. We exploit the directional control of the guided growth for the parallel production of multiple radial p-n heterojunctions and probe their optoelectronic properties. The devices exhibit a rectifying behavior with photovoltaic characteristics upon illumination. Guided nanowire heterostructures enable the bottom-up assembly of complex semiconductor structures with controlled electronic and optoelectronic properties.

  3. Optimal color design of psychological counseling room by design of experiments and response surface methodology.

    Science.gov (United States)

    Liu, Wenjuan; Ji, Jianlin; Chen, Hua; Ye, Chenyu

    2014-01-01

    Color is one of the most powerful aspects of a psychological counseling environment. Little scientific research has been conducted on color design and much of the existing literature is based on observational studies. Using design of experiments and response surface methodology, this paper proposes an optimal color design approach for transforming patients' perception into color elements. Six indices, pleasant-unpleasant, interesting-uninteresting, exciting-boring, relaxing-distressing, safe-fearful, and active-inactive, were used to assess patients' impression. A total of 75 patients participated, including 42 for Experiment 1 and 33 for Experiment 2. 27 representative color samples were designed in Experiment 1, and the color sample (L = 75, a = 0, b = -60) was the most preferred one. In Experiment 2, this color sample was set as the 'central point', and three color attributes were optimized to maximize the patients' satisfaction. The experimental results show that the proposed method can get the optimal solution for color design of a counseling room.

  4. Application of the MCNPX-McStas interface for shielding calculations and guide design at ESS

    Science.gov (United States)

    Klinkby, E. B.; Knudsen, E. B.; Willendrup, P. K.; Lauritzen, B.; Nonbøl, E.; Bentley, P.; Filges, U.

    2014-07-01

    Recently, an interface between the Monte Carlo code MCNPX and the neutron ray-tracing code MCNPX was developed [1, 2]. Based on the expected neutronic performance and guide geometries relevant for the ESS, the combined MCNPX-McStas code is used to calculate dose rates along neutron beam guides. The generation and moderation of neutrons is simulated using a full scale MCNPX model of the ESS target monolith. Upon entering the neutron beam extraction region, the individual neutron states are handed to McStas via the MCNPX-McStas interface. McStas transports the neutrons through the beam guide, and by using newly developed event logging capability, the neutron state parameters corresponding to un-reflected neutrons are recorded at each scattering. This information is handed back to MCNPX where it serves as neutron source input for a second MCNPX simulation. This simulation enables calculation of dose rates in the vicinity of the guide. In addition the logging mechanism is employed to record the scatterings along the guides which is exploited to simulate the supermirror quality requirements (i.e. m-values) needed at different positions along the beam guide to transport neutrons in the same guide/source setup.

  5. Computer-designed surgical guide template compared with free-hand operation for mesiodens extraction in premaxilla using "trapdoor" method.

    Science.gov (United States)

    Hu, Ying Kai; Xie, Qian Yang; Yang, Chi; Xu, Guang Zhou

    2017-06-01

    The aim of this study was to introduce a novel method of mesiodens extraction using a vascularized pedicled bone flap by piezosurgery and to compare the differences between a computer-aided design surgical guide template and free-hand operation.A total of 8 patients with mesiodens, 4 with a surgical guide (group I), and 4 without it (group II) were included in the study. The surgical design was to construct a trapdoor pedicle on the superior mucoperiosteal attachment with application of piezosurgery. The bone lid was repositioned after mesiodens extraction. Group I patients underwent surgeries based on the preoperative planning with surgical guide templates, while group II patients underwent free-hand operation. The outcome variables were success rate, intraoperative time, anterior nasal spine (ANS) position, changes of nasolabial angle (NLA), and major complications. Data from the 2 groups were compared by SPSS 17.0, using Wilcoxon test.The operative time was significantly shorter in group I patients. All the mesiodentes were extracted successfully and no obvious differences of preoperative and postoperative ANS position and NLA value were found in both groups. The patients were all recovered uneventfully.Surgical guide templates can enhance clinical accuracy and reduce operative time by facilitating accurate osteotomies.

  6. Application of the MCNPX-McStas interface for shielding calculations and guide design at ESS

    DEFF Research Database (Denmark)

    Klinkby, Esben Bryndt; Bergbäck Knudsen, Erik; Willendrup, Peter Kjær

    2013-01-01

    Recently, an interface between the Monte Carlo code MCNPX and the neutron ray-tracing code MCNPX was developed[1]. Based on the expected neutronic performance and guide geometries relevant for the ESS, the combined MCNPX-McStas code is used to calculate dose rates along neutron beam guides....... The generation and moderation of neutrons is simulated using a full scale MCNPX model of the ESS target monolith. Upon entering the beam extraction region, the individual neutron states are handed to McStas via the MCNPX-McStas interface. McStas transports the neutrons through the beam guide and by using newly...

  7. Application of the MCNPX-McStas interface for shielding calculations and guide design at ESS

    DEFF Research Database (Denmark)

    Klinkby, Esben Bryndt; Bergbäck Knudsen, Erik; Willendrup, Peter Kjær

    2014-01-01

    Recently, an interface between the Monte Carlo code MCNPX and the neutron ray-tracing code MCNPX was developed [1, 2]. Based on the expected neutronic performance and guide geometries relevant for the ESS, the combined MCNPX-McStas code is used to calculate dose rates along neutron beam guides....... The generation and moderation of neutrons is simulated using a full scale MCNPX model of the ESS target monolith. Upon entering the neutron beam extraction region, the individual neutron states are handed to McStas via the MCNPX-McStas interface. McStas transports the neutrons through the beam guide...

  8. Guiding brain tumor resection using surface-enhanced Raman scattering nanoparticles and a hand-held Raman scanner.

    Science.gov (United States)

    Karabeber, Hazem; Huang, Ruimin; Iacono, Pasquale; Samii, Jason M; Pitter, Ken; Holland, Eric C; Kircher, Moritz F

    2014-10-28

    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-enhanced Raman scattering (SERS) nanoparticles, to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model. In a simulated intraoperative scenario, we tested both a static Raman imaging device and a mobile, hand-held Raman scanner. We show that SERS image-guided resection is more accurate than resection using white light visualization alone. Both methods complemented each other, and correlation with histology showed that SERS nanoparticles accurately outlined the extent of the tumors. Importantly, the hand-held Raman probe not only allowed near real-time scanning, but also detected additional microscopic foci of cancer in the resection bed that were not seen on static SERS images and would otherwise have been missed. This technology has a strong potential for clinical translation because it uses inert gold-silica SERS nanoparticles and a hand-held Raman scanner that can guide brain tumor resection in the operating room.

  9. Design and validation of a CT-guided robotic system for lung cancer brachytherapy.

    Science.gov (United States)

    Dou, Huaisu; Jiang, Shan; Yang, Zhiyong; Sun, Luqing; Ma, Xiaodong; Huo, Bin

    2017-09-01

    Currently, lung brachytherapy in clinical setting is a complex procedure. Operation accuracy depends on accurate positioning of the template; however, it is difficult to guarantee the positioning accuracy manually. Application of robotic-assisted systems can simplify the procedure and improve the manual positioning accuracy. Therefore, a novel CT-guided robotic system was developed to assist the lung cancer brachytherapy. A four degree-of-freedom (DOF) robot, controlled by a lung brachytherapy treatment planning system (TPS) software, was designed and manufactured to assist the template positioning. Target position of the template can be obtained from the treatment plan, thus the robot is driven to the target position automatically. The robotic system was validated in both the laboratory and the CT environment. In laboratory environment, a 3D laser tracker and an inertial measurement unit (IMU) were used to measure the mechanical accuracy in air, which includes positioning accuracy and position repeatability. Working reliability was also validated in this procedure by observing the response reliability and calculating the position repeatability. Imaging artifacts and accuracy of the robot registration were validated in the CT environment by using an artificial phantom with fiducial markers. CT images were obtained and used to test the image artifact and calculate the registration accuracy. Phantom experiments were conducted to test the accuracy of needle insertion by using a transparent hydrogel phantom with a high imitation artificial phantom. Also, the efficiency was validated in this procedure by comparing time costs in manual positioning with robotic positioning under the same experimental conditions. The robotic system achieved the positioning accuracy of 0.28 ± 0.25 mm and the position repeatability of 0.09 ± 0.11 mm. Experimental results showed that the robot was CT-compatible and responded reliably to the control commands. The mean registration accuracy

  10. Novel modeling framework to guide design of optimal dosing strategies for β-lactamase inhibitors.

    Science.gov (United States)

    Bhagunde, Pratik; Chang, Kai-Tai; Hirsch, Elizabeth B; Ledesma, Kimberly R; Nikolaou, Michael; Tam, Vincent H

    2012-05-01

    The scarcity of new antibiotics against drug-resistant bacteria has led to the development of inhibitors targeting specific resistance mechanisms, which aim to restore the effectiveness of existing agents. However, there are few guidelines for the optimal dosing of inhibitors. Extending the utility of mathematical modeling, which has been used as a decision support tool for antibiotic dosing regimen design, we developed a novel mathematical modeling framework to guide optimal dosing strategies for a beta-lactamase inhibitor. To illustrate our approach, MK-7655 was used in combination with imipenem against a clinical isolate of Klebsiella pneumoniae known to produce KPC-2. A theoretical concept capturing fluctuating susceptibility over time was used to define a novel pharmacodynamic index (time above instantaneous MIC [T>MIC(i)]). The MK-7655 concentration-dependent MIC reduction was characterized by using a modified sigmoid maximum effect (E(max))-type model. Various dosing regimens of MK-7655 were simulated to achieve escalating T>MIC(i) values in the presence of a clinical dose of imipenem (500 mg every 6 h). The effectiveness of these dosing exposures was subsequently validated by using a hollow-fiber infection model (HFIM). An apparent trend in the bacterial response was observed in the HFIM with increasing T>MIC(i) values. In addition, different dosing regimens of MK-7655 achieving a similar T>MIC(i) (69%) resulted in comparable bacterial killing over 48 h. The proposed framework was reasonable in predicting the in vitro activity of a novel beta-lactamase inhibitor, and its utility warrants further investigations.

  11. Changes in the design, fabrication and setting of guide tube support pins in alloy X750; Evolution de la conception, de la fabrication et du montage des broches de fixation des tubes guides de grappes en alliage X750

    Energy Technology Data Exchange (ETDEWEB)

    Benhamou, C.; Chambrin, J.L. [FRAMATOME ANP, 92 - Paris-La-Defence (France); Todeschini, P. [Electricite de France (EDF/RD/MMC), 77 - Moret sur Loing (France); Champredonde, J. [Electricite de France (EDF/SQR/DMT), 91 - Evry (France); Lemaire, E. [Electricite de France (EDF/CAPE), 93 - Saint-Denis (France)

    2004-07-01

    As a consequence of a problem of stress corrosion cracking (SCC) encountered on guide tube support pins (GTSP) of first generation (1982) and of second generation (1987), EDF and Framatome decided in mars 1988 to launch an important program involving a complete overhaul of the design, the material used, the fabrication and the setting in reactor of GTSP. This program has led to the implementation in 900 MWe and 1300 MWe PWR of a new tube guide support pin called NG89. This implementation began in 1989, now 15 years later, 40% of the operating GTSP in 900 MWe and 1300 MWe PWR are of NG89 type, the oldest ones cumulate 105000 hours in service without negative feedback experience. The main features of the NG89 is: - to be made from an alloy X-750 containing boron (from 25 to 45 ppm) - to have a SCC threshold set at 720 MPa - to be machined from metal bars completely treated, - to have a rolling of the fillets, and - to undergo a shot blasting on the zones of the surface the most acted upon. (A.C.)

  12. Surface integral formulations for the design of plasmonic nanostructures.

    Science.gov (United States)

    Forestiere, Carlo; Iadarola, Giovanni; Rubinacci, Guglielmo; Tamburrino, Antonello; Dal Negro, Luca; Miano, Giovanni

    2012-11-01

    Numerical formulations based on surface integral equations (SIEs) provide an accurate and efficient framework for the solution of the electromagnetic scattering problem by three-dimensional plasmonic nanostructures in the frequency domain. In this paper, we present a unified description of SIE formulations with both singular and nonsingular kernel and we study their accuracy in solving the scattering problem by metallic nanoparticles with spherical and nonspherical shape. In fact, the accuracy of the numerical solution, especially in the near zone, is of great importance in the analysis and design of plasmonic nanostructures, whose operation critically depends on the manipulation of electromagnetic hot spots. Four formulation types are considered: the N-combined region integral equations, the T-combined region integral equations, the combined field integral equations and the null field integral equations. A detailed comparison between their numerical solutions obtained for several nanoparticle shapes is performed by examining convergence rate and accuracy in both the far and near zone of the scatterer as a function of the number of degrees of freedom. A rigorous analysis of SIE formulations and their limitations can have a high impact on the engineering of numerous nano-scale optical devices such as plasmon-enhanced light emitters, biosensors, photodetectors, and nanoantennas.

  13. High Surface Area Ceria Nanoparticles via Hydrothermal Synthesis Experiment Design

    Directory of Open Access Journals (Sweden)

    Stanislav Kurajica

    2016-01-01

    Full Text Available Hydrothermal synthesis of CeO2 was optimized on two reactant concentrations and synthesis temperature and duration, in order to achieve material having the greatest specific surface area (SSA. Taguchi method of experimental design was employed in evaluation of the relative importance of synthesis parameters. CeO2 nanoparticles were characterized using X-ray diffraction, nitrogen adsorption-desorption isotherms, and scanning electron microscopy. Optimum conditions for obtaining particles with greater SSA were calculated according to Taguchi’s model “the-higher-the-better.” Synthesis temperature was found to be the only parameter significant for enabling nanoparticles with greater SSA. Mesoporous nanocrystalline ceria with SSA as great as 226 m2 g−1 was achieved, which is unprecedented for the hydrothermally synthesized ceria. The reason for this achievement was found in temperature dependence of the diffusion coefficient which, when low, favors nucleation yielding with fine particles, while when high it favors crystal growth and formation of one-dimensional structures. The occurrence of 1D-structure in sample exhibiting the smallest SSA was confirmed. Very fine crystallites with crystallite size as low as 5.9 nm have been obtained being roughly inverse proportional to SSA. Selected samples were tested as catalyst for soot oxidation. Catalyst morphology turned out to be decisive factor for catalytic activity.

  14. Application of the MCNPX-McStas interface for shielding calculations and guide design at ESS

    OpenAIRE

    Klinkby, Esben Bryndt; Willendrup, Peter Kjær; Bergbäck Knudsen, Erik; Lauritzen, Bent; Nonbøl, Erik; Bentley, Philip; Filges, Uwe

    2013-01-01

    Recently, an interface between the Monte Carlo code MCNPX and the neutron ray-tracing code MCNPX was developed [1, 2]. Based on the expected neutronic performance and guide geometries relevant for the ESS, the combined MCNPX-McStas code is used to calculate dose rates along neutron beam guides. The generation and moderation of neutrons is simulated using a full scale MCNPX model of the ESS target monolith. Upon entering the neutron beam extraction region, the individual neutron states are han...

  15. Real-time Accurate Surface Reconstruction Pipeline for Vision Guided Planetary Exploration Using Unmanned Ground and Aerial Vehicles

    Science.gov (United States)

    Almeida, Eduardo DeBrito

    2012-01-01

    This report discusses work completed over the summer at the Jet Propulsion Laboratory (JPL), California Institute of Technology. A system is presented to guide ground or aerial unmanned robots using computer vision. The system performs accurate camera calibration, camera pose refinement and surface extraction from images collected by a camera mounted on the vehicle. The application motivating the research is planetary exploration and the vehicles are typically rovers or unmanned aerial vehicles. The information extracted from imagery is used primarily for navigation, as robot location is the same as the camera location and the surfaces represent the terrain that rovers traverse. The processed information must be very accurate and acquired very fast in order to be useful in practice. The main challenge being addressed by this project is to achieve high estimation accuracy and high computation speed simultaneously, a difficult task due to many technical reasons.

  16. Serial removal of caries lesions from tooth occlusal surfaces using near-IR image-guided IR laser ablation

    Science.gov (United States)

    Chan, Kenneth H.; Tom, Henry; Darling, Cynthia L.; Fried, Daniel

    2015-02-01

    Previous studies have established that caries lesions can be imaged with high contrast without the interference of stains at near-IR wavelengths greater than 1300-nm. It has been demonstrated that computer controlled laser scanning systems utilizing IR lasers operating at high pulse repetition rates can be used for serial imaging and selective removal of caries lesions. In this study, we report our progress towards the development of algorithms for generating rasterized ablation maps from near-IR reflectance images for the removal of natural lesions from tooth occlusal surfaces. An InGaAs camera and a filtered tungsten-halogen lamp producing near-IR light in the range of 1500-1700-nm were used to collect crosspolarization reflectance images of tooth occlusal surfaces. A CO2 laser operating at a wavelength of 9.3- μm with a pulse duration of 10-15-μs was used for image-guided ablation.

  17. Conceptual Design and Architecture of Mars Exploration Rover (MER) for Seismic Experiments Over Martian Surfaces

    Science.gov (United States)

    Garg, Akshay; Singh, Amit

    2012-07-01

    Keywords: MER, Mars, Rover, Seismometer Mars has been a subject of human interest for exploration missions for quite some time now. Both rover as well as orbiter missions have been employed to suit mission objectives. Rovers have been preferentially deployed for close range reconnaissance and detailed experimentation with highest accuracy. However, it is essential to strike a balance between the chosen science objectives and the rover operations as a whole. The objective of this proposed mechanism is to design a vehicle (MER) to carry out seismic studies over Martian surface. The conceptual design consists of three units i.e. Mother Rover as a Surrogate (Carrier) and Baby Rovers (two) as seeders for several MEMS-based accelerometer / seismometer units (Nodes). Mother Rover can carry these Baby Rovers, having individual power supply with solar cells and with individual data transmission capabilities, to suitable sites such as Chasma associated with Valles Marineris, Craters or Sand Dunes. Mother rover deploys these rovers in two opposite direction and these rovers follow a triangulation pattern to study shock waves generated through firing tungsten carbide shells into the ground. Till the time of active experiments Mother Rover would act as a guiding unit to control spatial spread of detection instruments. After active shock experimentation, the babies can still act as passive seismometer units to study and record passive shocks from thermal quakes, impact cratering & landslides. Further other experiments / payloads (XPS / GAP / APXS) can also be carried by Mother Rover. Secondary power system consisting of batteries can also be utilized for carrying out further experiments over shallow valley surfaces. The whole arrangement is conceptually expected to increase the accuracy of measurements (through concurrent readings) and prolong life cycle of overall experimentation. The proposed rover can be customised according to the associated scientific objectives and further

  18. Coupling of guided Surface Plasmon Polaritons to proximal self-assembled InGaAs Quantum Dots

    CERN Document Server

    Bracher, Gregor; Blauth, Mäx; Jakubeit, Clemens; Müller, Kai; Koblmüller, Gregor; Bichler, Max; Kaniber, Michael; Finley, Jonathan J

    2012-01-01

    We present investigations of the propagation length of guided surface plasmon polaritons along Au waveguides on GaAs and their coupling to near surface InGaAs self-assembled quantum dots. Our results reveal surface plasmon propagation lengths ranging from 13.4 {\\pm} 1.7 {\\mu}m to 27.5 {\\pm} 1.5 {\\mu}m as the width of the waveguide increases from 2-5 {\\mu}m. Experiments performed on active structures containing near surface quantum dots clearly show that the propagating plasmon mode excites the dot, providing a new method to spatially image the surface plasmon mode. We use low temperature confocal microscopy with polarization control in the excitation and detection channel. After excitation, plasmons propagate along the waveguide and are scattered into the far field at the end. By comparing length and width evolution of the waveguide losses we determine the plasmon propagation length to be 27.5 {\\pm} 1.5 {\\mu}m at 830 nm (for a width of 5 {\\mu}m), reducing to 13.4 {\\pm} 1.7 {\\mu}m for a width of 2 {\\mu}m. For ...

  19. Design, Implementation and Analysis of Learner-Centered Guided In-Service Programme for Technical Teacher Education

    OpenAIRE

    Tiia Rüütmann; Hants Kipper

    2014-01-01

    The design of learner-centered guided in-service program for technical teacher education has been launched at Estonian Centre for Engineering Pedagogy at Tallinn University of Technology. The aim of the program has been facilitating the initial in-service teaching experience, involving mentoring, peer support and cognitive apprenticeship. The emphasis has been on teaching for knowledge application, including the choice of content and processes, motivation, reflection, problem-solving, choice ...

  20. Experimental innovations in surface science a guide to practical laboratory methods and instruments

    CERN Document Server

    Yates, John T

    2015-01-01

    This book is a new edition of a classic text on experimental methods and instruments in surface science. It offers practical insight useful to chemists, physicists, and materials scientists working in experimental surface science. This enlarged second edition contains almost 300 descriptions of experimental methods. The more than 50 active areas with individual scientific and measurement concepts and activities relevant to each area are presented in this book. The key areas covered are: Vacuum System Technology, Mechanical Fabrication Techniques, Measurement Methods, Thermal Control, Delivery of Adsorbates to Surfaces, UHV Windows, Surface Preparation Methods, High Area Solids, Safety. The book is written for researchers and graduate students.

  1. Photovoltaic (PV) building design guide. Collection of worldwide cases of photovoltaic power generation buildings; PV kenchiku design guide. Sekai no taiyoko hatsuden kenchiku jireishu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-09-20

    This paper notices design possibility of PV buildings, and describes attempts to grasp the building integrated PV (BIPV) system in terms of total building design. The paper sets the principal object in providing photographs, specifications, and design data of the cases especially excellent in design sense, wherein, among the buildings adopting the photovoltaic power generation system, the handling of solar cell panels is integrated with the design of the building. Symbolic significance possessed by building patterns is great, and the symbolism and message expression over the environment are the important interests. Working on the BIPV from these viewpoints requires a number of hints in the design aspects, not to speak of the fundamental knowledge about photovoltaic power generation. This paper is intended to present the minimum necessary fundamental knowledge about PV systems, introduce excellent actual examples that can call for attention to photovoltaic power generation systems, and provide clues to proceeding to the next step toward the introduction thereof. The cases introduced in the paper include 36 PV cases in overseas countries, and 15 cases in Japan. (NEDO)

  2. Catalysis by Design Using Surface Organometallic Nitrogen-Containing Fragments

    KAUST Repository

    Hamzaoui, Bilel

    2016-06-14

    The aim of this thesis is to explore the chemistry of well-defined silica-supported group 4 and group 5 complexes that contain one or more multiply-bonded nitrogen atoms. Such species have been recognized as crucial intermediates in many catalytic reactions (e.g. hydroaminoalkylation, olefin hydrogenation, imine metathesis…). The first chapter provided a bibliographic overview of the preparation and the reactivity of group 4 and 5 complexes towards hydroaminoalkylation and imine metathesis catalysis. The second chapter deals with the isolation and the characterization of a series of well-defined group 4 ƞ2-imine complexes surfaces species. 2D solid-state NMR (1H–13C HETCOR, Multiple Quantum) experiments have revealed consistently a unique structural rearrangement, viz azametallacycle occurring on the immobilized metal-amido ligands. Hydrogenolysis of the sole Zr-C bond in such species gives selectively a silica-supported zirconium monohydride that can perform the catalytic hydrogenation of olefins. The third chapter examines the mechanistic studies of the intermolecular hydroaminoalkylation using SOMC to identify the key metallacyclic surface intermediates (silica-supported three-membred and five-membered). The catalyst was regenerated by protonolysis and afforded pure amine. Catalytic testing of a selection of amine compounds with variable electronic properties was carried out. The fourth chapter deals with the generation and the characterization of well-defined silica-supported zirconium-imido complexes. The resulting species effectively catalyzes imine/imine cross-metathesis and thus considered as the first heterogeneous catalysts active for imine metathesis reaction. The fifth chapter studies the reaction of SBA15.1100 ºC with dry aniline and derivatives leading to opening strained siloxane bridges into acid-base paired functionalities (formation of N-phenylsilanamine-silanol pairs). This approach was successfully applied to the design of a series of

  3. Chemistry - Toward efficient hydrogen production at surfaces

    DEFF Research Database (Denmark)

    Nørskov, Jens Kehlet; Christensen, Claus H.

    2006-01-01

    Calculations are providing a molecular picture of hydrogen production on catalytic surfaces and within enzymes, knowledge that may guide the design of new, more efficient catalysts for the hydrogen economy.......Calculations are providing a molecular picture of hydrogen production on catalytic surfaces and within enzymes, knowledge that may guide the design of new, more efficient catalysts for the hydrogen economy....

  4. Electrostatic surface guiding of cold polar molecules with a single charged wire

    Institute of Scientific and Technical Information of China (English)

    Deng Lian-Zhong; Xia Yong; Yin Jian-Ping

    2007-01-01

    This paper proposes a scheme to guide cold polar molecules by using a single charged wire half embanked in an insulating substrate and a homogeneous bias electric field,which is generated by a plate capacitor composed of two infinite parallel metal plates.The spatial distributions of the electrostatic field produced by the combination of the charged wire and the plate capacitor and the corresponding Stark potentials(including dipole forces) for metastable CO molecules are calculated,the relationships between the electric field and the parameters of our charged-wire layout are analysed.It also studies the influences of the insulator on the electric field distribution and the discharge effect.This study shows that the proposed scheme can be used to guide cold polar molecules in the weak-field-seeking states,and to form various molecule-optical elements,such as molecular funnel,molecular beam-splitters and molecule interferometer,even to construct a variety of integrated molecule-optical elements and their molecule chips.

  5. Chinese teaching guide language design art%语文教学导语设计艺术初探

    Institute of Scientific and Technical Information of China (English)

    陆玉婷

    2015-01-01

    语文课堂教学是一门艺术,而课堂教学过程中首要环节导语设计更是艺术中的艺术。在《教育方法与艺术全书》中有对导语相对科学的定义:“导语就是导入新课的语言,它是教师在讲授新课之前,有目的、有启发性、鼓动性、概括力、感染力的教学语言。”①可见导语是语文课堂教学不可或缺的组成部分。%The language classroom teaching is an art, and the first steps in the process of classroom teaching guide language of art design is art. In "the book of education methods and art, the definition of relative scientific guide language:" guide language is the language of the new lesson to import, it is a teacher in the teaching of new class before, purposeful, enlightening, motivational, recapitulate, appeal of teaching language."① Guide language is an integral part of the language classroom teaching.

  6. Fabrication and optical design of pyramid microstructure on the base of light guide used for the backlight module

    Science.gov (United States)

    Chang, Jee-Gong; Liu, Chien-Wei; Fang, Yu-Bin; Lu, Jian-Ming; Li, Wang-Long; Ju, Shin-Pon

    2010-10-01

    This paper proposed the pyramid microstructure (PYM) used on the base of the light guide as the micro-optical components to replace the conventional diffuser dot made by direct etching on the steel stamper. The PYM is made by MEMS technology, which uses silicon wafer as original mold of PYM and to replicate it on Ni micro-mold by using electroforming method. The effective optical design tool is used to find the optimal distribution of the PYM, which integrates the random microstructure generation scheme developed based on the molecular dynamics method and the optical commercial software. The SEM images show the intact PYM can be produced on the Si micro-mold and replicated fully on the Ni micro-mold by the electroforming process. The intact PYM on the base of the light guide can also be produced by the injection molding showing the complete transformation of the Ni micro-mold to the light guide. The luminance measurement of a 2.4 inches backlight module with 4 LEDs shows the average luminance of 4769 nit with 86.3% uniformity for the PYM on the base of light guide, which is 10% higher than that for the diffuser dot microstructure.

  7. VR-based training and assessment in ultrasound-guided regional anesthesia: from error analysis to system design.

    LENUS (Irish Health Repository)

    2011-01-01

    If VR-based medical training and assessment is to improve patient care and safety (i.e. a genuine health gain), it has to be based on clinically relevant measurement of performance. Metrics on errors are particularly useful for capturing and correcting undesired behaviors before they occur in the operating room. However, translating clinically relevant metrics and errors into meaningful system design is a challenging process. This paper discusses how an existing task and error analysis was translated into the system design of a VR-based training and assessment environment for Ultrasound Guided Regional Anesthesia (UGRA).

  8. Technical Support Document: Development of the Advanced Energy Design Guide for K-12 Schools--30% Energy Savings

    Energy Technology Data Exchange (ETDEWEB)

    Pless, S.; Torcellini, P.; Long, N.

    2007-09-01

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for K-12 School Buildings (K-12 AEDG), a design guidance document intended to provide recommendations for achieving 30% energy savings in K-12 Schools over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The 30% energy savings target is the first step toward achieving net-zero energy schools; schools that, on an annual basis, draw from outside sources less or equal energy than they generate on site from renewable energy sources.

  9. Launch and Functional Considerations Guiding the Scaling and Design of Rigid Inflatable Habitat Modules

    Science.gov (United States)

    Bell, L.

    2002-01-01

    for modules with diameters of approximately 45 ft. or more. Smaller dimensions will severely limit maximum sight lines, creating claustrophobic conditions. Equipment racks and other elements typically located around internal parameters will further reduce open areas, and vertical circulation access ways between floor levels will diminish usable space even more. However this scheme can work very well for larger diameter habitats, particularly for surface applications where a relatively wide-based/low height module is to be landed vertically. The banana split option. A longitudinal floor orientation can serve very satisfactorily for modules with diameters of 15 ft. or more. Unlike the bologna slice's circular floors, the rectangular spaces offer considerable versatility to accommodate diverse equipment and functional arrangements. Modules smaller than 15 ft. in diameter (the International Space Station standard) will be incompatible with efficient equipment rack design and layouts due to tight-radius wall curvatures. Beyond the 15 ft. diameters, it is logical to scale the modules at dimensional increments based upon the number of desired floors, allowing approximately 8-9 ft. of height/level. Current SICSA Mars mission planning advocates development of new launchers with payload accommodations for 45 ft. diameter, 200 metric ton cargo elements. This large booster will offer launch economies along with habitat scaling advantages. Launch system design efficiencies are influenced by the amount of functional drag that results as the vehicle passes through the Earth's atmosphere. These drag losses are subject to a "cubed-squared law". As the launchcraft's external dimensions increase, its surface area increases with the square of the dimension, while the volume increases with the cube. Since drag is a function of surface, not volume, increasing the vehicle size will reduce proportional drag losses. For this reason, the huge Saturn V Moon rocket experienced relatively low

  10. The combination of digital surface scanners and cone beam computed tomography technology for guided implant surgery using 3Shape implant studio software: a case history report.

    Science.gov (United States)

    Lanis, Alejandro; Álvarez Del Canto, Orlando

    2015-01-01

    The incorporation of virtual engineering into dentistry and the digitization of information are providing new perspectives and innovative alternatives for dental treatment modalities. The use of digital surface scanners with surgical planning software allows for the combination of the radiographic, prosthetic, surgical, and laboratory fields under a common virtual scenario, permitting complete digital treatment planning. In this article, the authors present a clinical case in which a guided implant surgery was performed based on a complete digital surgical plan combining the information from a cone beam computed tomography scan and the virtual simulation obtained from the 3Shape TRIOS intraoral surface scanner. The information was imported to and combined in the 3Shape Implant Studio software for guided implant surgery planning. A surgical guide was obtained by a 3D printer, and the surgical procedure was done using the Biohorizons Guided Surgery Kit and its protocol.

  11. Sliding Mode Control Design for a Class of SISO Systems with Uncertain Sliding Surface

    Directory of Open Access Journals (Sweden)

    Guofeng Wang

    2013-01-01

    Full Text Available The problem of designing a sliding mode controller with uncertain sliding surface for a class of uncertain single-input-single-output systems is studied. The design case is handled by using the invariant transformation first in order to separate the sliding mode and the reaching mode of the sliding mode control system. It is shown that the sliding mode design needs not to consider the uncertainties of the sliding surface, which can be handled in the reaching phase design. The results generalize the robust design of the reaching phase such that one specific reaching phase design may agree with several sliding surfaces.

  12. A new algorithm for designing developable Bézier surfaces

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xing-wang; WANG Guo-jin

    2006-01-01

    A new algorithm is presented that generates developable Bézier surfaces through a Bézier curve called a directrix. The algorithm is based on differential geometry theory on necessary and sufficient conditions for a surface which is developable, and on degree evaluation formula for parameter curves and linear independence for Bernstein basis. No nonlinear characteristic equations have to be solved. Moreover the vertex for a cone and the edge of regression for a tangent surface can be obtained easily.Aumann's algorithm for developable surfaces is a special case of this paper.

  13. Optically Designed Anodised Aluminium Surfaces: Microstructural and Electrochemical Aspects

    DEFF Research Database (Denmark)

    Gudla, Visweswara Chakravarthy

    under high frequency anodising, highly reflecting, bright and glossy white anodised aluminium surfaces were generated for the first time. Further, these white anodised surfaces were conventionally dyed to generate new appearances based on pastel colours. The work presented in this thesis is mainly......-13). The outcome of the work is presented in the last chapter (Chapter 15). The results from white anodising of the Al surfaces, which is the primary goal of this thesis and also the generation of a new set of pastel coloured anodised surfaces is presented. The optical characterization of these white anodised...

  14. Informatics guided discovery of surface structure-chemistry relationships in catalytic nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Andriotis, Antonis N., E-mail: andriot@iesl.forth.gr [Institute of Electronic Structure and Laser, FORTH, P.O. Box 1527, 71110 Heraklio, Crete (Greece); Mpourmpakis, Giannis, E-mail: gmpourmp@pitt.edu [Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15621 (United States); Broderick, Scott, E-mail: broderick.scott@gmail.com; Rajan, Krishna, E-mail: krajan@iastate.edu [Materials Science and Engineering, Iowa State University, Ames, Iowa 50011 (United States); Datta, Somnath, E-mail: somnath.datta@louisville.edu [Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, Kentucky 40202 (United States); Sunkara, Mahendra, E-mail: mahendra@louisville.edu [Department of Chemical Engineering, University of Louisville, Louisville, Kentucky 40202 (United States); Menon, Madhu, E-mail: super250@uky.edu [Department of Physics and Astronomy and Center for Computational Sciences, University of Kentucky, Lexington, Kentucky 40506 (United States)

    2014-03-07

    A data driven discovery strategy based on statistical learning principles is used to discover new correlations between electronic structure and catalytic activity of metal surfaces. From the quantitative formulations derived from this informatics based model, a high throughput computational framework for predicting binding energy as a function of surface chemistry and adsorption configuration that bypasses the need for repeated electronic structure calculations has been developed.

  15. Choice of seond-order response surface designs for logistic and Poisson regression models

    OpenAIRE

    Johnson, Rachel T.; Montgomery, Douglas C.

    2009-01-01

    Response surface methodology is widely used for process development and optimisation, product design, and as part of the modern framework for robust parameter design. For normally distributed responses, the standard second-order designs such as the central composite design and the Box-Behnken design have realtively high D and G efficiencies. In situations where these designs are inappropriate, standard computer software cen be used to construct D-optimal and I-optimal designs for fitting s...

  16. Guided-mode resonant filters and reflectors: Principles, design, and fabrication

    Science.gov (United States)

    Niraula, Manoj

    angular full-width at half-maximum linewidth of 9.5° compared to a linewidth of 0.1° for classical incidence. Slow angular variation of the central wavelength with full conical incidence arises via a corresponding slow angular variation of the resonant second diffraction orders driving the pertinent leaky modes. Moreover, full conical incidence maintains a profile with a single passband as opposed to the formation of two passbands characteristic of resonant subwavelength gratings under classical incidence. Our experimental results demonstrate excellent stability in angle, spectral profile, linewidth, and efficiency. Finally, we propose a novel method of design and fabrication of photonic lattices that incorporates the best of both worlds: a polarized resonant grating can be designed and converted to its unpolarized lattice equivalent using the same design parameters to obtain a similar performance. We show this in context of a single-layer polarized bandpass filter operating at 1550 nm with 100% transmission efficiency. An unpolarized square-hole lattice with identical parameters operates as a bandpass filter at 1560 nm with 70% transmission efficiency. Moreover, conventional laser interference lithography technique for mask patterning is limited to circular-hole photoresist lattice. We propose a method to lay down a metal hard-mask by lifting-off patterned photoresist in two steps for a square-hole lattice. Our comprehensive study provides new principles for easy design and fabrication of square-hole photonic lattices for unpolarized guided-mode resonance applications. (Abstract shortened by ProQuest.).

  17. DESIGN TECHNOLOGY FOR INJECTION MOLD PARTING SURFACE BASED ON CASES AND KNOWLEDGE

    Institute of Scientific and Technical Information of China (English)

    Yu Tongmin; Li Guanhua; Li Youmin; Lan Jian

    2005-01-01

    On the basis of the comprehensive analysis about the automatic generation of the injection mold parting surface, the parting surface design method which introduces knowledge and casebased reasoning (CBR) into the computer-aided design is described by combining with the actual characteristic in injection mold design, and the design process of case-based reasoning method is also given. A case library including the information of parting surface is built with the index of main shape features. The automatic design of the mold parting surface is realized combined with the forward-reasoning method and the similarity solution procedure. The rule knowledge library is also founded including the knowledge, principles and experiences for parting surface design. An example is used to show the validity of the method, and the quality and the efficiency of the mold design are improved.

  18. Macromolecular surface design: photopatterning of functional stable nitrile oxides.

    Science.gov (United States)

    Altintas, Ozcan; Glassner, Mathias; Rodriguez-Emmenegger, Cesar; Welle, Alexander; Trouillet, Vanessa; Barner-Kowollik, Christopher

    2015-05-04

    The efficient trapping of photogenerated thioaldehydes with functional shelf-stable nitrile oxides in a 1,3-dipolar cycloaddition is a novel and versatile photochemical strategy for polymer end-group functionalization and surface modification under mild and equimolar conditions. The modular ligation in solution was followed in detail by electrospray ionization mass spectrometry (ESI-MS). X-ray photoelectron spectroscopy (XPS) was employed to analyze the functionalized surfaces, whereas time-of-flight secondary-ion mass spectrometry (ToF-SIMS) confirmed the spatial control of the surface functionalization using a micropatterned shadow mask. Polymer brushes were grown from the surface in a spatially confined regime by surface-initiated atom transfer radical polymerization (SI-ATRP) as confirmed by TOF-SIMS, XPS as well as ellipsometry. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Computing variable bounds in the conceptual design phase of guided weapon systems

    NARCIS (Netherlands)

    Weiss, M.; Buco, D.

    2012-01-01

    The performance of guided weapon systems is primarily expressed by the end-of-flight effect, routinely approximated by the miss distance. It is however equally important that certain system variables of interest are kept within given bounds all along the duration of the flight. In this paper, we pro

  20. The Dual Language Program Planner: A Guide for Designing and Implementing Dual Language Programs.

    Science.gov (United States)

    Howard, Elizabeth R.; Olague, Natalie; Rogers, David

    This guide offers a framework to facilitate the planning process for dual language programs, assuming at least a basic working knowledge of the central characteristics and essential features of dual language models. It provides an overview of the various models that serve linguistically diverse student populations, defining the term dual language…

  1. Designing a bone health and soy focus group discussion guide based on the health belief model

    Science.gov (United States)

    Focus groups were used to assess the knowledge and skills of women in order to support curricula development. The Health Belief Model was applied to the discussion guide to enhance focus group findings and applications. Constructs related to perceived susceptibility, severity, benefits, and barriers...

  2. Computing variable bounds in the conceptual design phase of guided weapon systems

    NARCIS (Netherlands)

    Weiss, M.; Buco, D.

    2012-01-01

    The performance of guided weapon systems is primarily expressed by the end-of-flight effect, routinely approximated by the miss distance. It is however equally important that certain system variables of interest are kept within given bounds all along the duration of the flight. In this paper, we

  3. Guided access cavity preparation using cone-beam computed tomography and optical surface scans - an ex vivo study

    DEFF Research Database (Denmark)

    Buchgreitz, J; Buchgreitz, M; Mortensen, D

    2016-01-01

    . An apical canal preparation was created to simulate remnants of an apical root canal that acted as the target for a drill path. The test blocks were surface scanned, and merged with a CBCT scan, and a guide rail was made. A pathway for the bur was created through a metal sleeve within the guide rail...... into dentine. The distance was measured between the centres of the performed drill path and the apical target by two examiners. A maximum distance of 0.7 mm was defined based on the radius of the bur (0.6 mm) and the radius of a root canal just visible on a radiograph (0.1 mm). The t-test was used...... for evaluation, and intra- and inter-examiner reproducibility was expressed by intraclass correlation coefficients. RESULTS: The mean distance between the drill path and the target was significantly lower than 0.7 mm, and null hypothesis H0 : μ = 0.7 was rejected (CI 95%: 0.31;0.49, P

  4. Building bridges between theory and practice in medical education using a design-based research approach: AMEE Guide No. 60.

    Science.gov (United States)

    Dolmans, Diana H J M; Tigelaar, D

    2012-01-01

    Medical education research has grown enormously over the past 20 years, but it does not sufficiently make use of theories, according to influential leaders and researchers in this field. In this AMEE Guide, it is argued that design-based research (DBR) studies should be conducted much more in medical education design research because these studies both advance the testing and refinement of theories and advance educational practice. In this Guide, the essential characteristics of DBR as well as how DBR differs from other approach such as formative evaluation are explained. It is also explained what the pitfalls and challenges of DBR are. The main challenges deal with how to insure that DBR studies reveal findings that are of a broader relevance than the local situation and how to insure that DBR contributes toward theory testing and refinement. An example of a series of DBR studies on the design of a teaching portfolio in higher education that is aimed at stimulating a teacher's professional development is described, to illustrate how DBR studies actually work in practice. Finally, it is argued that DBR-studies could play an important role in the advancement of theory and practice in the two broad domains of designing or redesigning work-based learning environments and assessment programs.

  5. Agent-oriented Embedded Control System Design and Development of a Vision-based Automated Guided Vehicle

    Directory of Open Access Journals (Sweden)

    Wu Xing

    2012-07-01

    Full Text Available This paper presents a control system design and development approach for a vision‐based automated guided vehicle (AGV based on the multi‐agent system (MAS methodology and embedded system resources. A three‐phase agent‐oriented design methodology Prometheus is used to analyse system functions, construct operation scenarios, define agent types and design the MAS coordination mechanism. The control system is then developed in an embedded implementation containing a digital signal processor (DSP and an advanced RISC machine (ARM by using the multitasking processing capacity of multiple microprocessors and system services of a real‐time operating system (RTOS. As a paradigm, an onboard embedded controller is designed and developed for the AGV with a camera detecting guiding landmarks, and the entire procedure has a high efficiency and a clear hierarchy. A vision guidance experiment for our AGV is carried out in a space‐limited laboratory environment to verify the perception capacity and the onboard intelligence of the agent‐oriented embedded control system.

  6. Agent-Oriented Embedded Control System Design and Development of a Vision-Based Automated Guided Vehicle

    Directory of Open Access Journals (Sweden)

    Wu Xing

    2012-07-01

    Full Text Available This paper presents a control system design and development approach for a vision-based automated guided vehicle (AGV based on the multi-agent system (MAS methodology and embedded system resources. A three-phase agent-oriented design methodology Prometheus is used to analyse system functions, construct operation scenarios, define agent types and design the MAS coordination mechanism. The control system is then developed in an embedded implementation containing a digital signal processor (DSP and an advanced RISC machine (ARM by using the multitasking processing capacity of multiple microprocessors and system services of a real-time operating system (RTOS. As a paradigm, an onboard embedded controller is designed and developed for the AGV with a camera detecting guiding landmarks, and the entire procedure has a high efficiency and a clear hierarchy. A vision guidance experiment for our AGV is carried out in a space-limited laboratory environment to verify the perception capacity and the onboard intelligence of the agent-oriented embedded control system.

  7. Design and Application of Surface Modification at Molecular Scale

    Institute of Scientific and Technical Information of China (English)

    CHEN Miao; XUE Qun-Ji; ZHOU Feng; GUAN Fei; LIU Wei-Min

    2004-01-01

    The structuring of surfaces on a nanoscale level-both chemically and topographically has become an increasingly relevant field of research in nanotechnology with widespread application potential in various fields of science ( e. g.surface engineering, electronics, biotechnology, optics). Two examples on surface modification at molecular scale with self-assembly monolayers are shown: ( 1 ) Chemically attaching ultra-thin polymer films through the self-assembly of silane fictionalized copolymer have been approved in this article. (2) The patterned films with microstructures on different substrates have been prepared through micro-contact printing technique and electro polymerization.

  8. Surface-plasmon-polariton wave propagation guided by a metal slab in a sculptured nematic thin film

    CERN Document Server

    Faryad, Muhammad

    2010-01-01

    Surface-plasmon-polariton~(SPP) wave propagation guided by a metal slab in a periodically nonhomogeneous sculptured nematic thin film~(SNTF) was studied theoretically. The morphologically significant planes of the SNTF on both sides of the metal slab could either be aligned or twisted with respect to each other. The canonical boundary-value problem was formulated, solved for SPP-wave propagation, and examined to determine the effect of slab thickness on the multiplicity and the spatial profiles of SPP waves. Decrease in slab thickness was found to result in more intense coupling of two metal/SNTF interfaces. But when the metal slab becomes thicker, the coupling between the two interfaces reduces and SPP waves localize to one of the two interfaces. The greater the coupling between the two metal/SNTF interfaces, the smaller is the phase speed.

  9. SAGE SOLVENT ALTERNATIVES GUIDE: SYSTEM IMPROVEMENTS FOR SELECTING INDUSTRIAL SURFACE CLEANING ALTERNATIVES

    Science.gov (United States)

    The paper describes computer software, called SAGE, that can provide not only cleaning recommendations but also general information on various surface cleaning options. In short, it is an advisory system which can provide users with vital information on the cleaning process optio...

  10. Ultrasound-guided three-dimensional needle steering in biological tissue with curved surfaces

    NARCIS (Netherlands)

    Abayazid, M.; Lopes da Frota Moreira, P.; Shahriari, N.; Patil, S.; Alterovitz, Ron; Misra, S.

    2015-01-01

    In this paper, we present a system capable of automatically steering a bevel-tipped flexible needle under ultrasound guidance toward a physical target while avoiding a physical obstacle embedded in gelatin phantoms and biological tissue with curved surfaces. An ultrasound pre-operative scan is perfo

  11. 设计理念——观念引导设计%Design Ideology:Thought Guide Design

    Institute of Scientific and Technical Information of China (English)

    蒋雯

    2012-01-01

      The values of industrial design were boiled down to five different types of design ideology: art-centered design, function-centered design, business-centered design, human-centered design and nature-centered design. This article explained the basic idea and the constitution of these five ideologies,and used examples to describe the features of them.%  将工业设计的价值观念归纳为以艺术为中心、以功能为中心、以商业为中心、以人为中心和一自然为中心五种设计理念,阐述了这五种设计理念的基本思想和构成,并通过实例说明其特征。

  12. Antimicrobial design of titanium surface that kill sessile bacteria but support stem cells adhesion

    Science.gov (United States)

    Zhu, Chen; Bao, Ni-Rong; Chen, Shuo; Zhao, Jian-Ning

    2016-12-01

    Implant-related bacterial infection is one of the most severe postoperative complications in orthopedic or dental surgery. In this context, from the perspective of surface modification, increasing efforts have been made to enhance the antibacterial capability of titanium surface. In this work, a hierarchical hybrid surface architecture was firstly constructed on titanium surface by two-step strategy of acid etching and H2O2 aging. Then silver nanoparticles were firmly immobilized on the hierarchical surface by ion implantation, showing no detectable release of silver ions from surface. The designed titanium surface showed good bioactivity. More importantly, this elaborately designed titanium surface can effectively inactivate the adherent S. aureus on surface by virtue of a contact-killing mode. Meanwhile, the designed titanium surface can significantly facilitate the initial adhesion and spreading behaviors of bone marrow mesenchymal stem cells (MSCs) on titanium. The results suggested that, the elaborately designed titanium surface might own a cell-favoring ability that can help mammalian cells win the initial adhesion race against bacteria. We hope the present study can provide a new insight for the better understanding and designing of antimicrobial titanium surface, and pave the way to satisfying clinical requirements.

  13. Masters Thesis- Criticality Alarm System Design Guide with Accompanying Alarm System Development for the Radioisotope Production Laboratory in Richland, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Greenfield, Bryce A. [Univ. of New Mexico, Albuquerque, NM (United States)

    2009-12-01

    A detailed instructional manual was created to guide criticality safety engineers through the process of designing a criticality alarm system (CAS) for Department of Energy (DOE) hazard class 1 and 2 facilities. Regulatory and technical requirements were both addressed. A list of design tasks and technical subtasks are thoroughly analyzed to provide concise direction for how to complete the analysis. An example of the application of the design methodology, the Criticality Alarm System developed for the Radioisotope Production Laboratory (RPL) of Richland, Washington is also included. The analysis for RPL utilizes the Monte Carlo code MCNP5 for establishing detector coverage in the facility. Significant improvements to the existing CAS were made that increase the reliability, transparency, and coverage of the system.

  14. Developing a theory to guide the process of designing information retrieval systems

    DEFF Research Database (Denmark)

    Sonnenwald, Diane H.

    1992-01-01

    This research attempts to develop a descriptive design model that accounts for communication among users, designers, and developer throughout the design process. A pilot study has been completed and a preliminary model that represents a first step in understanding participants' evolving perceptio...... and expectations of the design process and its outcomes is described in this paper....

  15. Design and application of model for training ultrasound-guided vascular cannulation in pediatric patients.

    Science.gov (United States)

    Pérez-Quevedo, O; López-Álvarez, J M; Limiñana-Cañal, J M; Loro-Ferrer, J F

    2016-01-01

    Central vascular cannulation is not a risk-free procedure, especially in pediatric patients. Newborn and infants are small and low-weighted, their vascular structures have high mobility because of tissue laxity and their vessels are superficial and with small diameter. These characteristics, together with the natural anatomical variability and poor collaboration of small children, make this technique more difficult to apply. Therefore, ultrasound imaging is increasingly being used to locate vessels and guide vascular access in this population. (a) To present a model that simulates the vascular system for training ultrasound-guided vascular access in pediatrics patients; (b) to ultrasound-guided vascular cannulation in the model. The model consisted of two components: (a) muscular component: avian muscle, (b) vascular component: elastic tube-like structure filled with fluid. 864 ecoguided punctures was realized in the model at different vessel depth and gauge measures were simulated, for two medical operators with different degree of experience. The average depth and diameter of vessel cannulated were 1.16 (0.42)cm and 0.43 (0.1)cm, respectively. The average number of attempts was of 1.22 (0.62). The percentage of visualization of the needle was 74%. The most frequent maneuver used for the correct location, was the modification of the angle of the needle and the relocation of the guidewire in 24% of the cases. The average time for the correct cannulations was 41 (35.8)s. The more frequent complications were the vascular perforation (11.9%) and the correct vascular puncture without possibility of introducing the guidewire (1.2%). The rate of success was 96%. The model simulates the anatomy (vascular and muscular structures) of a pediatric patient. It is cheap models, easily reproducible and a useful tool for training in ultrasound-guided puncture and cannulation. Copyright © 2015 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  16. Simple equations guide high-frequency surface-wave investigation techniques

    Science.gov (United States)

    Xia, J.; Xu, Y.; Chen, C.; Kaufmann, R.D.; Luo, Y.

    2006-01-01

    We discuss five useful equations related to high-frequency surface-wave techniques and their implications in practice. These equations are theoretical results from published literature regarding source selection, data-acquisition parameters, resolution of a dispersion curve image in the frequency-velocity domain, and the cut-off frequency of high modes. The first equation suggests Rayleigh waves appear in the shortest offset when a source is located on the ground surface, which supports our observations that surface impact sources are the best source for surface-wave techniques. The second and third equations, based on the layered earth model, reveal a relationship between the optimal nearest offset in Rayleigh-wave data acquisition and seismic setting - the observed maximum and minimum phase velocities, and the maximum wavelength. Comparison among data acquired with different offsets at one test site confirms the better data were acquired with the suggested optimal nearest offset. The fourth equation illustrates that resolution of a dispersion curve image at a given frequency is directly proportional to the product of a length of a geophone array and the frequency. We used real-world data to verify the fourth equation. The last equation shows that the cut-off frequency of high modes of Love waves for a two-layer model is determined by shear-wave velocities and the thickness of the top layer. We applied this equation to Rayleigh waves and multi-layer models with the average velocity and obtained encouraging results. This equation not only endows with a criterion to distinguish high modes from numerical artifacts but also provides a straightforward means to resolve the depth to the half space of a layered earth model. ?? 2005 Elsevier Ltd. All rights reserved.

  17. Surface-Modified Electrodes: Enhancing Performance Guided by Insitu Spectroscopy and Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Chueh, William [Stanford Univ., CA (United States)

    2016-12-01

    The aim of this project is to understand the nature of active sites and degradation mechanisms in solid-oxide fuel cells cathodes. Using Co and Fe-based perovskite oxides as model systems, we developed a comprehensive understanding of the active site and degradation. In particular, we correlated cation segregation, precipitation and surface reconstruction to electrochemical activity and stability. We show that in conventional materials, the most active cathodes are not the most stable ones. A novel strategy of cation segregation buffer layer was proposed and developed to overcome this limitation. A nanoscale barrier layer was inserted a few nanometer below the surface of the cathodes which prevents the cations from diffusing from the bulk to the surface. We report a LSCF-based cathode with record performance and stability, reach an impressive 0.03 Ω cm2 at 650 °C in air. This modification strategy is expected to lead to more active and stable solid-oxide fuel cells, and ultimately lead to lower cost in commercial systems.

  18. Design and performance of optimal detectors for guided wave structural health monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Dib, G.; Udpa, L.

    2016-01-01

    Ultrasonic guided wave measurements in a long term structural health monitoring system are affected by measurement noise, environmental conditions, transducer aging and malfunction. This results in measurement variability which affects detection performance, especially in complex structures where baseline data comparison is required. This paper derives the optimal detector structure, within the framework of detection theory, where a guided wave signal at the sensor is represented by a single feature value that can be used for comparison with a threshold. Three different types of detectors are derived depending on the underlying structure’s complexity: (i) Simple structures where defect reflections can be identified without the need for baseline data; (ii) Simple structures that require baseline data due to overlap of defect scatter with scatter from structural features; (iii) Complex structure with dense structural features that require baseline data. The detectors are derived by modeling the effects of variabilities and uncertainties as random processes. Analytical solutions for the performance of detectors in terms of the probability of detection and false alarm are derived. A finite element model is used to generate guided wave signals and the performance results of a Monte-Carlo simulation are compared with the theoretical performance. initial results demonstrate that the problems of signal complexity and environmental variability can in fact be exploited to improve detection performance.

  19. Design and Optimization of the Slide Guide System of Hydraulic Press Based on Energy Loss Analysis

    Directory of Open Access Journals (Sweden)

    Mengdi Gao

    2016-06-01

    Full Text Available The clearances in the slide guide system of a hydraulic press are one of the significant factors affecting its accuracy. These clearances also affect the energy consumption of the press. An energy loss model that considers the oil leaks and friction associated with these clearances was proposed, and the size of clearances was optimized based on the model. The maximum allowable eccentric load and the energy loss on the wedge clearance condition were calculated to ensure the slide and guide pillars function properly. The stiffness of pillars and wear of guide rails were checked under an eccentric load condition. A case for rapid sheet metal forming with a 20 MN hydraulic press was examined. For this case, the optimum fit clearances were found to be approximately 0.4 mm. The energy loss under an eccentric load condition was increased by approximately 83% compared to a non-eccentric load condition. The pillars were optimized by reducing excessive stiffness, which served to decrease the pillar weight by nearly 20%.

  20. Design developing conceptual models blade with geometric combined surface

    OpenAIRE

    Juraev, T. H.; Bukhara Technological Institute of Engineering, Bukhara

    2013-01-01

    A conceptual model of the blade using the methods of geometricmodeling principles of industrial design and CAD technologies. Variants are functional use of the proposed model for various working bodies.

  1. Optically Designed Anodised Aluminium Surfaces: Microstructural and Electrochemical Aspects

    DEFF Research Database (Denmark)

    Gudla, Visweswara Chakravarthy

    the microstructure in order to impart light scattering ability to the anodised layer. Coatings based on Al-Zr and Al-Ti binary system were studied for their anodising behaviour with and without heat treatment. The structure evolution of the Al-Zr sputtered coatings and the effect of Si during heat treatment...... bright-anodised surfaces. Effect of pulse frequency, anodic and cathodic cycle potential values was systematically investigated. Characterization of surfaces and substrates was performed using Scanning and Transmission Electron Microscopy, Grazing-Incidence X-ray Diffraction, Glow Discharge Optical...

  2. CBR-Beta Design Procedure for Aggregate-Surfaced Airfield Pavements

    Science.gov (United States)

    2014-03-01

    ER D C/ G SL T R- 14 -6 CBR-Beta Design Procedure for Aggregate- Surfaced Airfield Pavements G eo te ch ni ca l a nd S tr uc tu re s...surfaces. The original flexible pavement design procedure of paved surfaces, which is based on the California Bearing Ratio (CBR) and the α-factor...Alpha-factor), was also extended and applied to the design and evaluation of aggregate-surfaced pavements . With the reformulation of the CBR-Alpha for

  3. CAD system for footwear design based on whole real 3D data of last surface

    Science.gov (United States)

    Song, Wanzhong; Su, Xianyu

    2000-10-01

    Two major parts of application of CAD in footwear design are studied: the development of last surface; computer-aided design of planar shoe-template. A new quasi-experiential development algorithm of last surface based on triangulation approximation is presented. This development algorithm consumes less time and does not need any interactive operation for precisely development compared with other development algorithm of last surface. Based on this algorithm, a software, SHOEMAKERTM, which contains computer aided automatic measurement, automatic development of last surface and computer aide design of shoe-template has been developed.

  4. DESIGN AND CALCULATION OF AERODROMECOAING WITH HEATED SURFACE LAYERS

    Directory of Open Access Journals (Sweden)

    Vadim G. Piskunov

    2009-04-01

    Full Text Available  The developed constructions with heated by surface layers for aerodromes and auto roads when developed composition of electroconductive concrete reinforced with chemical electrical conductive fibres being used was researched. The experimentally obtained characteristics of ended conductive concrete reinforced with fibers were presented. Calculation by developed heated construction of shell was made.

  5. Imaging Freeform Optical Systems Designed with NURBS Surfaces

    Science.gov (United States)

    2015-12-01

    Fortunately, an all-reflective corrector avoids the issues of chromatic aberration, which are severe for a refractive corrector over this...with NURBS Freeform Surfaces,” OSA Freeform Optics Conference, Renewable Energy and Environment Congress (2013). 16. M. P. Chrisp, B. Primeau, M

  6. Design parameters for measurements of local catalytic activity on surfaces

    DEFF Research Database (Denmark)

    Johansson, Martin; Johannessen, Tue; Jørgensen, Jan Hoffmann;

    2006-01-01

    Computational fluid dynamics in combination with experiments is used to characterize a gas sampling device for measurements of the local catalytic activity on surfaces. The device basically consists of a quartz capillary mounted concentrically inside an aluminum tube. Reactant gas is blown toward...

  7. Modeling, design, packing and experimental analysis of liquid-phase shear-horizontal surface acoustic wave sensors

    Science.gov (United States)

    Pollard, Thomas B

    Recent advances in microbiology, computational capabilities, and microelectromechanical-system fabrication techniques permit modeling, design, and fabrication of low-cost, miniature, sensitive and selective liquid-phase sensors and lab-on-a-chip systems. Such devices are expected to replace expensive, time-consuming, and bulky laboratory-based testing equipment. Potential applications for devices include: fluid characterization for material science and industry; chemical analysis in medicine and pharmacology; study of biological processes; food analysis; chemical kinetics analysis; and environmental monitoring. When combined with liquid-phase packaging, sensors based on surface-acoustic-wave (SAW) technology are considered strong candidates. For this reason such devices are focused on in this work; emphasis placed on device modeling and packaging for liquid-phase operation. Regarding modeling, topics considered include mode excitation efficiency of transducers; mode sensitivity based on guiding structure materials/geometries; and use of new piezoelectric materials. On packaging, topics considered include package interfacing with SAW devices, and minimization of packaging effects on device performance. In this work novel numerical models are theoretically developed and implemented to study propagation and transduction characteristics of sensor designs using wave/constitutive equations, Green's functions, and boundary/finite element methods. Using developed simulation tools that consider finite-thickness of all device electrodes, transduction efficiency for SAW transducers with neighboring uniform or periodic guiding electrodes is reported for the first time. Results indicate finite electrode thickness strongly affects efficiency. Using dense electrodes, efficiency is shown to approach 92% and 100% for uniform and periodic electrode guiding, respectively; yielding improved sensor detection limits. A numerical sensitivity analysis is presented targeting viscosity

  8. Guided-mode-resonance coupled localized surface plasmons for dually resonance enhanced Raman scattering sensing

    Science.gov (United States)

    Wang, Zheng; Liu, Chao; Li, Erwen; Chakravarty, Swapnajit; Xu, Xiaochuan; Wang, Alan X.; Fan, D. L.; Chen, Ray T.

    2017-02-01

    Raman scattering spectroscopy is a unique tool to probe vibrational, rotational, and other low-frequency modes of a molecular system and therefore could be utilized to identify chemistry and quantity of molecules. However, the ultralow efficient Raman scattering, which is only 1/109 1/1014 of the excitation light due to the small Raman scattering cross-sections of molecules, have significantly hindered its development in practical sensing applications. The discovery of surface-enhanced Raman scattering (SERS) in the 1970s and the significant progress in nanofabrication technique, provide a promising solution to overcome the inherent issues of Raman spectroscopy. It is found that In the vicinity of nanoparticles and their junctions, the Raman signals of molecules can be significantly improved by an enhancement factor as high as 1010, due to the ultrahigh electric field generated by the localized surface plasmons resonance (LSPR), where the intensity of Raman scattering is proportional to the |E|4. In this work, we propose and demonstrate a new approach combining LSPR from nanocapsules with densely assembled silver nanoparticles (NC-AgNPs) and guidemode- resonance (GMR) from dielectric photonic crystal slabs (PCSs) for SERS substrates with robustly high performance.

  9. How to Manage Asbestos in School Buildings: The AHERA Designated Person's Self Study Guide

    Science.gov (United States)

    This EPA document is designed to assist Asbestos Hazard Emergency Response Act (AHERA) designated persons in understanding their responsibilities to help local education agencies comply with federal asbestos in schools regulations.

  10. Oriented and Ordered Biomimetic Remineralization of the Surface of Demineralized Dental Enamel Using HAP@ACP Nanoparticles Guided by Glycine

    Science.gov (United States)

    Wang, Haorong; Xiao, Zuohui; Yang, Jie; Lu, Danyang; Kishen, Anil; Li, Yanqiu; Chen, Zhen; Que, Kehua; Zhang, Qian; Deng, Xuliang; Yang, Xiaoping; Cai, Qing; Chen, Ning; Cong, Changhong; Guan, Binbin; Li, Ting; Zhang, Xu

    2017-01-01

    Achieving oriented and ordered remineralization on the surface of demineralized dental enamel, thereby restoring the satisfactory mechanical properties approaching those of sound enamel, is still a challenge for dentists. To mimic the natural biomineralization approach for enamel remineralization, the biological process of enamel development proteins, such as amelogenin, was simulated in this study. In this work, carboxymethyl chitosan (CMC) conjugated with alendronate (ALN) was applied to stabilize amorphous calcium phosphate (ACP) to form CMC/ACP nanoparticles. Sodium hypochlorite (NaClO) functioned as the protease which decompose amelogenin in vivo to degrade the CMC-ALN matrix and generate HAP@ACP core-shell nanoparticles. Finally, when guided by 10 mM glycine (Gly), HAP@ACP nanoparticles can arrange orderly and subsequently transform from an amorphous phase to well-ordered rod-like apatite crystals to achieve oriented and ordered biomimetic remineralization on acid-etched enamel surfaces. This biomimetic remineralization process is achieved through the oriented attachment (OA) of nanoparticles based on non-classical crystallization theory. These results indicate that finding and developing analogues of natural proteins such as amelogenin involved in the biomineralization by natural macromolecular polymers and imitating the process of biomineralization would be an effective strategy for enamel remineralization. Furthermore, this method represents a promising method for the management of early caries in minimal invasive dentistry (MID).

  11. Oriented and Ordered Biomimetic Remineralization of the Surface of Demineralized Dental Enamel Using HAP@ACP Nanoparticles Guided by Glycine

    Science.gov (United States)

    Wang, Haorong; Xiao, Zuohui; Yang, Jie; Lu, Danyang; Kishen, Anil; Li, Yanqiu; Chen, Zhen; Que, Kehua; Zhang, Qian; Deng, Xuliang; Yang, Xiaoping; Cai, Qing; Chen, Ning; Cong, Changhong; Guan, Binbin; Li, Ting; Zhang, Xu

    2017-01-01

    Achieving oriented and ordered remineralization on the surface of demineralized dental enamel, thereby restoring the satisfactory mechanical properties approaching those of sound enamel, is still a challenge for dentists. To mimic the natural biomineralization approach for enamel remineralization, the biological process of enamel development proteins, such as amelogenin, was simulated in this study. In this work, carboxymethyl chitosan (CMC) conjugated with alendronate (ALN) was applied to stabilize amorphous calcium phosphate (ACP) to form CMC/ACP nanoparticles. Sodium hypochlorite (NaClO) functioned as the protease which decompose amelogenin in vivo to degrade the CMC-ALN matrix and generate HAP@ACP core-shell nanoparticles. Finally, when guided by 10 mM glycine (Gly), HAP@ACP nanoparticles can arrange orderly and subsequently transform from an amorphous phase to well-ordered rod-like apatite crystals to achieve oriented and ordered biomimetic remineralization on acid-etched enamel surfaces. This biomimetic remineralization process is achieved through the oriented attachment (OA) of nanoparticles based on non-classical crystallization theory. These results indicate that finding and developing analogues of natural proteins such as amelogenin involved in the biomineralization by natural macromolecular polymers and imitating the process of biomineralization would be an effective strategy for enamel remineralization. Furthermore, this method represents a promising method for the management of early caries in minimal invasive dentistry (MID). PMID:28079165

  12. Hand-guided 3D surface acquisition by combining simple light sectioning with real-time algorithms

    CERN Document Server

    Arold, Oliver; Willomitzer, Florian; Häusler, Gerd

    2014-01-01

    Precise 3D measurements of rigid surfaces are desired in many fields of application like quality control or surgery. Often, views from all around the object have to be acquired for a full 3D description of the object surface. We present a sensor principle called "Flying Triangulation" which avoids an elaborate "stop-and-go" procedure. It combines a low-cost classical light-section sensor with an algorithmic pipeline. A hand-guided sensor captures a continuous movie of 3D views while being moved around the object. The views are automatically aligned and the acquired 3D model is displayed in real time. In contrast to most existing sensors no bandwidth is wasted for spatial or temporal encoding of the projected lines. Nor is an expensive color camera necessary for 3D acquisition. The achievable measurement uncertainty and lateral resolution of the generated 3D data is merely limited by physics. An alternating projection of vertical and horizontal lines guarantees the existence of corresponding points in successi...

  13. Developing a theory to guide the process of designing information retrieval systems

    DEFF Research Database (Denmark)

    Sonnenwald, Diane H.

    1992-01-01

    This research attempts to develop a descriptive design model that accounts for communication among users, designers, and developer throughout the design process. A pilot study has been completed and a preliminary model that represents a first step in understanding participants' evolving perceptio...

  14. Flexible design in water and wastewater engineering--definitions, literature and decision guide.

    Science.gov (United States)

    Spiller, Marc; Vreeburg, Jan H G; Leusbrock, Ingo; Zeeman, Grietje

    2015-02-01

    Urban water and wastewater systems face uncertain developments including technological progress, climate change and urban development. To ensure the sustainability of these systems under dynamic conditions it has been proposed that technologies and infrastructure should be flexible, adaptive and robust. However, in literature it is often unclear what these technologies and infrastructure are. Furthermore, the terms flexible, adaptive and robust are often used interchangeably, despite important differences. In this paper we will i) define the terminology, ii) provide an overview of the status of flexible infrastructure design alternatives for water and wastewater networks and treatment, and iii) develop guidelines for the selection of flexible design alternatives. Results indicate that, with the exception of Net Present Valuation methods, there is little research available on the design and evaluation of technologies that can enable flexibility. Flexible design alternatives reviewed include robust design, phased design, modular design, modular/component platform design and design for remanufacturing. As developments in the water sector are driven by slow variables (climate change, urban development), rather than market forces, it is suggested that phased design or component platform designs are suitable for responding to change, while robust design is an option when operations face highly dynamic variability.

  15. PRESENTATION OF AN ARCHITECTURAL OBJECT DESIGNED BY WARPED SURFACES

    Directory of Open Access Journals (Sweden)

    VELJKOVIĆ Milica

    2015-06-01

    Full Text Available Due to the importance of good functional solutions and aesthetic appearance of an object, modeling in architecture is the subject of this study. Application of more modern materials in architecture allows us to perform various geometric surfaces in the production of facade and roof structures. With such complex objects, it is necessary to create detailed three-dimensional models, using some of the modern software package for modeling. This paper provides an example of creating a 3D model of a modern building in whose exterior we can recognize nondevelopmental (becoming warped line-generated surfaces, primarily cylindroids and conoids. The entire process of modeling and presenting an object using augmented reality was carried out using the modern software package for visualization in architecture.

  16. Designing porous metallic glass compact enclosed with surface iron oxides

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jae Young; Park, Hae Jin; Hong, Sung Hwan; Kim, Jeong Tae; Kim, Young Seok; Park, Jun-Young; Lee, Naesung [Hybrid Materials Center (HMC), Faculty of Nanotechnology and Advanced Materials Engineering, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul 143-747 (Korea, Republic of); Seo, Yongho [Graphene Research Institute (GRI) & HMC, Faculty of Nanotechnology and Advanced Materials Engineering, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul 143-747 (Korea, Republic of); Park, Jin Man, E-mail: jinman_park@hotmail.com [Global Technology Center, Samsung Electronics Co., Ltd, 129 Samsung-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do 443-742 (Korea, Republic of); Kim, Ki Buem, E-mail: kbkim@sejong.ac.kr [Hybrid Materials Center (HMC), Faculty of Nanotechnology and Advanced Materials Engineering, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul 143-747 (Korea, Republic of)

    2015-06-25

    Highlights: • Porous metallic glass compact was developed using electro-discharge sintering process. • Uniform PMGC can only be achieved when low electrical input energy was applied. • Functional iron-oxides were formed on the surface of PMGCs by hydrothermal technique. - Abstract: Porous metallic glass compact (PMGC) using electro-discharge sintering (EDS) process of gas atomized Zr{sub 41.2}Ti{sub 13.8}Cu{sub 12.5}Ni{sub 10}Be{sub 22.5} metallic glass powder was developed. The formation of uniform PMGC can only be achieved when low electrical input energy was applied. Functional iron-oxides were formed on the surface of PMGCs by hydrothermal technique. This finding suggests that PMGC can be applied in the new area such as catalyst via hydrothermal technique and offer a promising guideline for using the metallic glasses as a potential functional application.

  17. Friction reduction using discrete surface textures: principle and design

    Science.gov (United States)

    Hsu, Stephen M.; Jing, Yang; Hua, Diann; Zhang, Huan

    2014-08-01

    There have been many reports on the use of dimples, grooves, and other surface textures to control friction in sliding interfaces. The effectiveness of surface textures in friction reduction has been demonstrated in conformal contacts under high speed low load applications such as mechanical seals and automotive water pump seals, etc., resulting in reduced friction and longer durability. For sliding components with higher contact pressures or lower speeds, conflicting results were reported. Reasons for the inconsistency may be due to the differences in texture fabrication techniques, lack of dimple size and shape uniformity, and different tester used. This paper examines the basic principles on which surface textural patterns influence friction under the three principle lubrication regimes: hydrodynamic, elastohydrodynamic, and boundary lubrication regimes. Our findings suggest that each regime requires specific dimple size, shape, depth, and areal density to achieve friction reduction. Control experiments were also conducted to explore mechanisms of friction reduction. The dimple geometric shape and the dimple's orientation with respect to the sliding direction influence friction significantly. The underlying mechanisms for friction control via textures are discussed.

  18. Innovation Design of a Special CNC Machine Tool for Guide Disc%导盘数控机床的创新设计

    Institute of Scientific and Technical Information of China (English)

    关尚军; 杨克

    2012-01-01

    我国普通导盘机床传统的工件人工夹紧方式及人工推动主轴进给和分体式结构,已经不能满足导盘加工的高效、精密、自动化的技术要求.为此进行了导盘数控机床的创新设计.设计的机床能实现工件的自动夹紧,具有液控伸缩式主轴和整体式结构,机床的重复定位精度达到0.008 mm,表面粗糙度达到Ra1.6 μm.并采用了有源隔离技术,提高了数控系统的可靠性和稳定性.%In the last decade, Chinese original design of the normal NC machine tool, which emphasizes on the traditional manual clamping style for the workpiece, the manual impulse of the spindle feed stepless, and the structure of the split style, can not match the technical requirements for the efficiency, accuracy, and automation when producing guide disc. In this circumstance, a special NC guide disc machine tool was developed, and which achieved the goals of automatically clamping workpiece, telescopic hydraulic control spindle, and holistic structure design. The precision of the repositioning reaches at 0.008 mm and the surface roughness reaches at Ral. 6 μn. In the mean time, in order to improve the reliability and stability, the active isolation technology was adopted.

  19. Design, Implementation and Analysis of Learner-Centered Guided In-Service Programme for Technical Teacher Education

    Directory of Open Access Journals (Sweden)

    Tiia Rüütmann

    2014-03-01

    Full Text Available The design of learner-centered guided in-service program for technical teacher education has been launched at Estonian Centre for Engineering Pedagogy at Tallinn University of Technology. The aim of the program has been facilitating the initial in-service teaching experience, involving mentoring, peer support and cognitive apprenticeship. The emphasis has been on teaching for knowledge application, including the choice of content and processes, motivation, reflection, problem-solving, choice of educational technology, effective teaching methods, teaching models and strategies ཿ concepts, tools and procedures of the field of engineering, organized in ways enabling teachers to formulate real world problems, apply and solve them. The program has been implemented since 2012 and covers IGIP curriculum requirements. In the present article the designed program is described and analyzed.

  20. TGP, an extremely stable, non-aggregating fluorescent protein created by structure-guided surface engineering

    Science.gov (United States)

    Close, Devin W.; Don Paul, Craig; Langan, Patricia S.; Wilce, Matthew C.J.; Traore, Daouda A.K.; Halfmann, Randal; Rocha, Reginaldo C.; Waldo, Geoffery S.; Payne, Riley J.; Rucker, Joseph B.; Prescott, Mark; Bradbury, Andrew R.M.

    2014-01-01

    In this paper we describe the engineering and X-ray crystal structure of Thermal Green Protein (TGP), an extremely stable, highly soluble, non-aggregating green fluorescent protein. TGP is a soluble variant of the fluorescent protein eCGP123, which despite being highly stable, has proven to be aggregation-prone. The X-ray crystal structure of eCGP123, also determined within the context of this paper, was used to carry out rational surface engineering to improve its solubility, leading to TGP. The approach involved simultaneously eliminating crystal lattice contacts while increasing the overall negative charge of the protein. Despite intentional disruption of lattice contacts and introduction of high entropy glutamate side chains, TGP crystallized readily in a number of different conditions and the X-ray crystal structure of TGP was determined to 1.9 Å resolution. The structural reasons for the enhanced stability of TGP and eCGP123 are discussed. We demonstrate the utility of using TGP as a fusion partner in various assays and significantly, in amyloid assays in which the standard fluorescent protein, EGFP, is undesirable because of aberrant oligomerization. PMID:25287913

  1. Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structure-guided surface engineering.

    Science.gov (United States)

    Close, Devin W; Paul, Craig Don; Langan, Patricia S; Wilce, Matthew C J; Traore, Daouda A K; Halfmann, Randal; Rocha, Reginaldo C; Waldo, Geoffery S; Payne, Riley J; Rucker, Joseph B; Prescott, Mark; Bradbury, Andrew R M

    2015-07-01

    In this article, we describe the engineering and X-ray crystal structure of Thermal Green Protein (TGP), an extremely stable, highly soluble, non-aggregating green fluorescent protein. TGP is a soluble variant of the fluorescent protein eCGP123, which despite being highly stable, has proven to be aggregation-prone. The X-ray crystal structure of eCGP123, also determined within the context of this paper, was used to carry out rational surface engineering to improve its solubility, leading to TGP. The approach involved simultaneously eliminating crystal lattice contacts while increasing the overall negative charge of the protein. Despite intentional disruption of lattice contacts and introduction of high entropy glutamate side chains, TGP crystallized readily in a number of different conditions and the X-ray crystal structure of TGP was determined to 1.9 Å resolution. The structural reasons for the enhanced stability of TGP and eCGP123 are discussed. We demonstrate the utility of using TGP as a fusion partner in various assays and significantly, in amyloid assays in which the standard fluorescent protein, EGFP, is undesirable because of aberrant oligomerization.

  2. Droplets, Evaporation and a Superhydrophobic Surface: Simple Tools for Guiding Colloidal Particles into Complex Materials

    Directory of Open Access Journals (Sweden)

    Marcel Sperling

    2017-05-01

    Full Text Available The formation of complexly structured and shaped supraparticles can be achieved by evaporation-induced self-assembly (EISA starting from colloidal dispersions deposited on a solid surface; often a superhydrophobic one. This versatile and interesting approach allows for generating rather complex particles with corresponding functionality in a simple and scalable fashion. The versatility is based on the aspect that basically one can employ an endless number of combinations of components in the colloidal starting solution. In addition, the structure and properties of the prepared supraparticles may be modified by appropriately controlling the evaporation process, e.g., by external parameters. In this review, we focus on controlling the shape and internal structure of such supraparticles, as well as imparted functionalities, which for instance could be catalytic, optical or electronic properties. The catalytic properties can also result in self-propelling (supra-particles. Quite a number of experimental investigations have been performed in this field, which are compared in this review and systematically explained.

  3. Design Methodology And Performance Studies Of A Flexible Electrotextile Surface

    Directory of Open Access Journals (Sweden)

    Kayacan Ozan

    2015-09-01

    Full Text Available ‘The smart textiles’ concept has to develop products based not only on design, fashion and comfort but also in terms of functions. The novel electro-textiles in the market open up new trends in smart and interactive gadgets. ‘Easy to care and durability’ properties are among the most important features of these products. On the other hand, wearable electronic knitwear has been gaining the attention of both researchers and industrial sectors. Combining knitting technology with electronics may become a dominant trend in the future because of the wide application possibilities. This research is concerned primarily with the design methodology of knitted fabrics containing electrically conductive textiles and especially in-use performance studies. The structural characteristics of the fabrics have been evaluated to enhance the performance properties.

  4. On the Design of Suspended Roofs with Paraboloidal Surfaces

    Directory of Open Access Journals (Sweden)

    N. Ungureanu

    2006-01-01

    Full Text Available Some considerations concerning the design of the paraboloidal suspended roofs are made. The main geometric aspects are first time presented. For the roofs we propose, as pattern, the equivalent continuum membranes, and the efforts in the cable are determined by using the membrane efforts and their equations. Two examples are analyzed: elliptic paraboloide and hyperbolic paraboloide, with horizontal projection under the form of an ellipse.

  5. Reliability design of mechanical systems a guide for mechanical and civil engineers

    CERN Document Server

    Woo, Seongwoo

    2017-01-01

    This book describes basic reliability concepts – parametric ALT plan, failure mechanism and design, and reliability testing with acceleration factor and sample size equation. A generalized life-stress failure model with a new effort concept has been derived and recommended to calculate the acceleration factor of the mechanical system. The new sample size equation with the acceleration factor has also been derived to carry out the parametric ALT. This new parametric ALT should help a mechanical/civil engineer to uncover the design parameters affecting reliability during the design process of the mechanical system. Consequently, it should help companies to improve product reliability and avoid recalls due to the product/structure failures in the field. As the improper or missing design parameters in the design phase are experimentally identified by this new reliability design method - parametric ALT, the mechanical/civil engineering system might improve in reliability by the increase in lifetime and the reduc...

  6. Design and production of a new surface mount charge-integrating amplifier for CDF

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, C.; Drake, G.

    1991-01-01

    We present our experiences in designing and producing 26,000 new charge-integrating amplifiers for CDF, using surface-mount components. The new amplifiers were needed to instrument 920 new 24-channel CDF RABBIT boards, which are replacing an older design rendered obsolete by increases in the collision rate. Important design considerations were frequency response, physical size and cost. 5 refs.

  7. The ORNL Modulating Heat Pump Design Tool -- Mark IV User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    Rice, C.K.

    2001-09-27

    The ORNL Modulating Heat Pump Design Tool consists of a Modulating HPDM (Heat Pump Design Model) and a parametric-analysis (contour-data generating) front-end. Collectively the program is also referred to as MODCON which is in reference to the modulating and the contour data generating capabilities. The program was developed by Oak Ridge National Laboratory for the Department of Energy to provide a publicly-available system design tool for variable- and single-speed heat pumps.

  8. The ORNL Modulating Heat Pump Design Tool User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    Rice, C.K.

    2001-06-01

    The ORNL Modulating Heat Pump Design Tool consists of a Modulating HPDM (Heat Pump Design Model) and a parametric-analysis (contour-data generating) front-end. Collectively the program is also referred to as MODCON which is in reference to the modulating and the contour data generating capabilities. The program was developed by Oak Ridge National Laboratory for the Department of Energy to provide a publicly-available system design tool for variable- and single-speed heat pumps.

  9. Microgrid Design Toolkit (MDT) User Guide Software v1.2.

    Energy Technology Data Exchange (ETDEWEB)

    Eddy, John P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-08-01

    The Microgrid Design Toolkit (MDT) supports decision analysis for new ("greenfield") microgrid designs as well as microgrids with existing infrastructure. The current version of MDT includes two main capabilities. The first capability, the Microgrid Sizing Capability (MSC), is used to determine the size and composition of a new, grid connected microgrid in the early stages of the design process. MSC is focused on developing a microgrid that is economically viable when connected to the grid. The second capability is focused on designing a microgrid for operation in islanded mode. This second capability relies on two models: the Technology Management Optimization (TMO) model and Performance Reliability Model (PRM).

  10. An automatic grid generation approach over free-form surface for architectural design

    Institute of Scientific and Technical Information of China (English)

    苏亮; 祝顺来; 肖南; 高博青

    2014-01-01

    An essential step for the realization of free-form surface structures is to create an efficient structural gird that satisfies not only the architectural aesthetics, but also the structural performance. Employing the main stress trajectories as the representation of force flows on a free-form surface, an automatic grid generation approach is proposed for the architectural design. The algorithm automatically plots the main stress trajectories on a 3D free-form surface, and adopts a modified advancing front meshing technique to generate the structural grid. Based on the proposed algorithm, an automatic grid generator named “St-Surmesh” is developed for the practical architectural design of free-form surface structure. The surface geometry of one of the Sun Valleys in Expo Axis for the Expo Shanghai 2010 is selected as a numerical example for validating the proposed approach. Comparative studies are performed to demonstrate how different structural grids affect the design of a free-form surface structure.

  11. Wind or water turbine power augmentation using the system of guiding surfaces

    Science.gov (United States)

    Bashurin, V. P.; Budnikov, I. N.; Hatunkin, V. Yu; Klevtsov, V. A.; Ktitorov, L. V.; Lazareva, A. S.; Meshkov, E. E.; Novikova, I. A.; Pletenev, F. A.; Yanbaev, G. M.

    2016-04-01

    As fluid flows through a conventional wind or hydro turbine, it slows from losing energy to extraction from a turbine and spreads out to a wider area. This results in a loss of turbine efficiency. In order to exploit wind or water flow power more effectively, it was suggested to place the turbine inside a system of specially designed airfoils (‘a flow booster’). One part of the booster (‘a nozzle’) improves the turbine performance by speeding up the flow acting on the turbine blades. The other part of the accelerating system (‘a diffuser’) creates a field of low pressure behind the turbine which helps to draw more mass flow to the turbine and avoid the loss of efficiency due to flow deceleration. The flow booster accumulates the kinetic energy of the flow (e.g. river flow or wind) in a small volume where the smaller turbine can be installed. Another possible application of the booster could be the improvement of wind turbine efficiency during low wind period. The present paper also discusses the possibility of kinetic energy accumulation by the use of several accelerating systems of different sizes—the smaller one can be installed inside the bigger one. It helps to accumulate even more kinetic energy on the turbine blades. We call this method the kinetic energy cumulation. Lab and field experiments and CFD simulations of shrouded turbine demonstrate significant increase in velocity in comparison of those for conventional (bare) turbines.

  12. SU-E-J-55: End-To-End Effectiveness Analysis of 3D Surface Image Guided Voluntary Breath-Holding Radiotherapy for Left Breast

    Energy Technology Data Exchange (ETDEWEB)

    Lin, M; Feigenberg, S [University of Maryland School of Medicine, Baltimore, MD (United States)

    2015-06-15

    Purpose To evaluate the effectiveness of using 3D-surface-image to guide breath-holding (BH) left-side breast treatment. Methods Two 3D surface image guided BH procedures were implemented and evaluated: normal-BH, taking BH at a comfortable level, and deep-inspiration-breath-holding (DIBH). A total of 20 patients (10 Normal-BH and 10 DIBH) were recruited. Patients received a BH evaluation using a commercialized 3D-surface- tracking-system (VisionRT, London, UK) to quantify the reproducibility of BH positions prior to CT scan. Tangential 3D/IMRT plans were conducted. Patients were initially setup under free-breathing (FB) condition using the FB surface obtained from the untaged CT to ensure a correct patient position. Patients were then guided to reach the planned BH position using the BH surface obtained from the BH CT. Action-levels were set at each phase of treatment process based on the information provided by the 3D-surface-tracking-system for proper interventions (eliminate/re-setup/ re-coaching). We reviewed the frequency of interventions to evaluate its effectiveness. The FB-CBCT and port-film were utilized to evaluate the accuracy of 3D-surface-guided setups. Results 25% of BH candidates with BH positioning uncertainty > 2mm are eliminated prior to CT scan. For >90% of fractions, based on the setup deltas from3D-surface-trackingsystem, adjustments of patient setup are needed after the initial-setup using laser. 3D-surface-guided-setup accuracy is comparable as CBCT. For the BH guidance, frequency of interventions (a re-coaching/re-setup) is 40%(Normal-BH)/91%(DIBH) of treatments for the first 5-fractions and then drops to 16%(Normal-BH)/46%(DIBH). The necessity of re-setup is highly patient-specific for Normal-BH but highly random among patients for DIBH. Overall, a −0.8±2.4 mm accuracy of the anterior pericardial shadow position was achieved. Conclusion 3D-surface-image technology provides effective intervention to the treatment process and ensures

  13. Model Guided Design and Development Process for an Electronic Health Record Training Program.

    Science.gov (United States)

    He, Ze; Marquard, Jenna; Henneman, Elizabeth

    2016-01-01

    Effective user training is important to ensure electronic health record (EHR) implementation success. Though many previous studies report best practice principles and success and failure stories, current EHR training is largely empirically-based and often lacks theoretical guidance. In addition, the process of training development is underemphasized and underreported. A white paper by the American Medical Informatics Association called for models of user training for clinical information system implementation; existing instructional development models from learning theory provide a basis to meet this call. We describe in this paper our experiences and lessons learned as we adapted several instructional development models to guide our development of EHR user training. Specifically, we focus on two key aspects of this training development: training content and training process.

  14. Theory-Guided Design of Organic Electro-Optic Materials and Devices

    Directory of Open Access Journals (Sweden)

    Stephanie Benight

    2011-08-01

    Full Text Available Integrated (multi-scale quantum and statistical mechanical theoretical methods have guided the nano-engineering of controlled intermolecular electrostatic interactions for the dramatic improvement of acentric order and thus electro-optic activity of melt-processable organic polymer and dendrimer electro-optic materials. New measurement techniques have permitted quantitative determination of the molecular order parameters, lattice dimensionality, and nanoscale viscoelasticity properties of these new soft matter materials and have facilitated comparison of theoretically-predicted structures and thermodynamic properties with experimentally-defined structures and properties. New processing protocols have permitted further enhancement of material properties and have facilitated the fabrication of complex device structures. The integration of organic electro-optic materials into silicon photonic, plasmonic, and metamaterial device architectures has led to impressive new performance metrics for a variety of technological applications.

  15. Cyclone-Resistant Rural Primary School Construction - A Design Guide. Educational Building Report 7.

    Science.gov (United States)

    Sinnamon, Ian T.; Loo, G. A. van't

    One of a series of documents on design of disaster-resistant buildings, this publication treats construction of rural primary schools to resist destruction by wind and water from cyclones. Also appropriate for other buildings, material is aimed at rural primary schools because they are less likely to be professionally designed or supervised; the…

  16. Project Help. An Elementary Curriculum Guide Designed to Help Students Help Themselves.

    Science.gov (United States)

    Cranston School Dept., RI.

    This two-part curriculum is designed to teach elementary students basic life skills that will enable them to assume greater responsibility for themselves. Part 1, the primary curriculum, is designed for grades 3 and 4. Five units of instruction are included in the primary curriculum: home management, foods, personal cleanliness, sewing, and…

  17. Family and Consumer Sciences: A Facility Planning and Design Guide for School Systems.

    Science.gov (United States)

    Maryland State Dept. of Education, Baltimore.

    This document presents design concepts and considerations for planning and developing middle and high school family and consumer sciences education facilities. It includes discussions on family and consumer sciences education trends and the facility planning process. Design concepts explore multipurpose laboratories and spaces for food/nutrition…

  18. How To Manage Asbestos in School Buildings: AHERA Designated Person's Self-Study Guide.

    Science.gov (United States)

    Environmental Protection Agency, Seattle, WA.

    The Environmental Protection Agency (EPA) requires schools to appoint an asbestos management coordinator called the "AHERA (Asbestos Hazardous Emergency Response Act) designated person" (DP) who is responsible for a number of asbestos-related activities. This manual presents some recommendations designed to help those persons appointed…

  19. Design tools for a DNA-guided self-assembling carbon nanotube technology

    Science.gov (United States)

    Dwyer, C.; Johri, V.; Cheung, M.; Patwardhan, J.; Lebeck, A.; Sorin, D.

    2004-09-01

    The shift in technology away from silicon complementary metal-oxide semiconductors (CMOS) to novel nanoscale technologies requires new design tools. In this paper, we explore one particular nanotechnology: carbon nanotube transistors that are self-assembled into circuits by using DNA. We develop design tools and demonstrate how to use them to develop circuitry based on this nanotechnology.

  20. Cyclone-Resistant Rural Primary School Construction - A Design Guide. Educational Building Report 7.

    Science.gov (United States)

    Sinnamon, Ian T.; Loo, G. A. van't

    One of a series of documents on design of disaster-resistant buildings, this publication treats construction of rural primary schools to resist destruction by wind and water from cyclones. Also appropriate for other buildings, material is aimed at rural primary schools because they are less likely to be professionally designed or supervised; the…

  1. Using Importance-Performance Analysis to Guide Instructional Design of Experiential Learning Activities

    Science.gov (United States)

    Anderson, Sheri; Hsu, Yu-Chang; Kinney, Judy

    2016-01-01

    Designing experiential learning activities requires an instructor to think about what they want the students to learn. Using importance-performance analysis can assist with the instructional design of the activities. This exploratory study used importance-performance analysis in an online introduction to criminology course. There is limited…

  2. Conceptual design and sample preparation of electrode covered single glass macro-capillaries for studying the effect of an external electric field on particle guiding

    Energy Technology Data Exchange (ETDEWEB)

    Wartak, A. [Institute of Applied Physics, TU Wien, A-1040 Vienna (Austria); Bereczky, R.J., E-mail: bereczky.reka@atomki.mta.hu [Institute for Nuclear Research, Hungarian Academy of Sciences (ATOMKI), H-4026 Debrecen, P.O. Box 51 (Hungary); Kowarik, G. [Institute of Applied Physics, TU Wien, A-1040 Vienna (Austria); Tőkési, K. [Institute for Nuclear Research, Hungarian Academy of Sciences (ATOMKI), H-4026 Debrecen, P.O. Box 51 (Hungary); Aumayr, F. [Institute of Applied Physics, TU Wien, A-1040 Vienna (Austria)

    2015-07-01

    We present the design and construction of a macroscopic glass capillary covered by electrodes on the outside. With these new capillary targets it will be possible to study the influence of an external electric field on the process of guiding of charged particles through a capillary. The new degrees of freedoms will contribute to both a better fundamental understanding of the guiding phenomenon but might also be of use in practical applications.

  3. Application of Response Surface Methodology and Central Composite Inscribed Design for Modeling and Optimization of Marble Surface Quality

    Directory of Open Access Journals (Sweden)

    Sümeyra Cevheroğlu Çıra

    2016-01-01

    Full Text Available Factors affecting the final surface quality of polished marble are not yet fully understood. Clarifying these factors for optimization of multivariate polishing process by trial and error method is difficult, time-consuming, and costly task. In this study, the empirical practices were carried out using an experimental design, specifically, a central composite inscribed (CCI design. The factors considered in CCI design were belt speed, rotational speed, and pressure of the polishing head, and the responses were surface glossiness and roughness. Mathematical models describing responses were produced using experimental datasets, and analysis of variance (ANOVA was used to assess the fit of the models generated with the experimental data. For process optimization, desirability function analysis (DFA was used. This study has shown that the CCI could efficiently be applied for the modelling of polishing machine for surface quality of marble strips. Better surface quality generally resulted from lower belt speeds, which increased contact time between the abrasives and strips. Optimized surface quality for marble specimen was established.

  4. 一种导游服务型机器人设计%Design of Tour Guide Service Robot

    Institute of Scientific and Technical Information of China (English)

    倪文彬; 陆广华; 张毅

    2016-01-01

    According to the requirements of a science and technology museum,a guide service robot is designed. The robot is com ̄posed of a mechanical system, motion control system and sensor system. The mechanical structure of the robot is built, a motion control scheme is proposed based on researches on motion control card and stepping motor,a scheme of line searching and naviga ̄tion is designed based on the photoelectric sensor, and through the test and debugging, the line navigation program is optimized. Through experiments,the designed robot can be used to complete the welcome, line tracking navigation and voice guide function,and fulfils the expected requirements.%针对某科技馆提出的要求,设计了一种导游服务型机器人。该机器人由机械系统、运动控制系统、传感器系统组成。完成了移动底盘、手臂、头部等机械结构设计;通过对运动控制卡和步进电机特性的研究提出运动控制方案;设计了一种基于光电传感器的寻线导航方案,并通过试验调试对寻线导航方案进行优化。实验证明,机器人能够完成礼貌迎宾、巡线导航和语音导游功能。

  5. Design of an ultrasound-guided robotic brachytherapy needle insertion system

    CERN Document Server

    Hungr, Nikolai; Zemiti, Nabil; Tripodi, Nathanael

    2009-01-01

    In this paper we describe a new robotic brachytherapy needle-insertion system that is designed to replace the template used in the manual technique. After a brief review of existing robotic systems, we describe the requirements that we based our design upon. A detailed description of the proposed system follows. Our design is capable of positioning and inclining a needle within the same workspace as the manual template. To help improve accuracy, the needle can be rotated about its axis during insertion into the prostate. The system can be mounted on existing steppers and also easily accommodates existing seed dispensers, such as the Mick Applicator.

  6. Graphene Based Terahertz Absorber Designed With Effective Surface Conductivity Approach

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Pizzocchero, Filippo; Booth, Tim

    Young field of terahertz (THz) science and technology demands new materials and devices, such as filters, modulators, polarization converters and absorbers. Graphene, a recently discovered single-atom-thick material, provides exciting properties for functional terahertz applications. Graphene...... conductivity and how to use it in optical design. We demonstrate a tunable THz perfect absorber, which consists of continuous graphene various structured graphene metamaterials above a metal mirror. Changing the Fermi level from 0 eV to 0.5 eV allows for drastic changes in absorbance from less than 0.1 to 1...... in the working range. We demonstrate the possibility of the absorber bandwidth control with the metamaterial’s unit cell geometry. The results of fabrication and characterization of the THz graphene metamaterials based absorbers will be presented at the conference....

  7. Clinical efficacy and safety of surface imaging guided radiosurgery (SIG-RS) in the treatment of benign skull base tumors.

    Science.gov (United States)

    Lau, Steven K M; Patel, Kunal; Kim, Teddy; Knipprath, Erik; Kim, Gwe-Ya; Cerviño, Laura I; Lawson, Joshua D; Murphy, Kevin T; Sanghvi, Parag; Carter, Bob S; Chen, Clark C

    2017-04-01

    Frameless, surface imaging guided radiosurgery (SIG-RS) is a novel platform for stereotactic radiosurgery (SRS) wherein patient positioning is monitored in real-time through infra-red camera tracking of facial topography. Here we describe our initial clinical experience with SIG-RS for the treatment of benign neoplasms of the skull base. We identified 48 patients with benign skull base tumors consecutively treated with SIG-RS at a single institution between 2009 and 2011. Patients were diagnosed with meningioma (n = 22), vestibular schwannoma (n = 20), or nonfunctional pituitary adenoma (n = 6). Local control and treatment-related toxicity were retrospectively assessed. Median follow-up was 65 months (range 61-72 months). Prescription doses were 12-13 Gy in a single fraction (n = 18), 8 Gy × 3 fractions (n = 6), and 5 Gy × 5 fractions (n = 24). Actuarial tumor control rate at 5 years was 98%. No grade ≥3 treatment-related toxicity was observed. Grade ≤2 toxicity was associated with symptomatic lesions (p = 0.049) and single fraction treatment (p = 0.005). SIG-RS for benign skull base tumors produces clinical outcomes comparable to conventional frame-based SRS techniques while enhancing patient comfort.

  8. Surface-plasmon-polariton waves guided by the uniformly moving planar interface of a metal film and dielectric slab

    CERN Document Server

    Mackay, Tom G

    2010-01-01

    We explored the effects of relative motion on the excitation of surface-plasmon-polariton (SPP) waves guided by the planar interface of a metal film and a dielectric slab, both materials being isotropic and homogeneous. Electromagnetic phasors in moving and non-moving reference frames were related directly using the corresponding Lorentz transformations. Our numerical studies revealed that, in the case of a uniformly moving dielectric slab, the angle of incidence for SPP-wave excitation is highly sensitive to (i) the ratio $\\beta$ of the speed of motion to speed of light in free space and (ii) the direction of motion. When the direction of motion is parallel to the plane of incidence, the SPP wave is excited by $p$-polarized (but not $s$-polarized) incident plane waves for low and moderate values of $\\beta$, while at higher values of $\\beta$ the total reflection regime breaks down. When the direction of motion is perpendicular to the plane of incidence, the SPP wave is excited by $p$-polarized incident plane ...

  9. Distillation and Air Stripping Designs for the Lunar Surface

    Science.gov (United States)

    Boul, Peter J.; Lange, Kevin E.; Conger, Bruce; Anderson, Molly

    2009-01-01

    Air stripping and distillation are two different gravity-based methods, which may be applied to the purification of wastewater on the lunar base. These gravity-based solutions to water processing are robust physical separation techniques, which may be advantageous to many other techniques for their simplicity in design and operation. The two techniques can be used in conjunction with each other to obtain high purity water. The components and feed compositions for modeling waste water streams are presented in conjunction with the Aspen property system for traditional stage distillation models and air stripping models. While the individual components for each of the waste streams will vary naturally within certain bounds, an analog model for waste water processing is suggested based on typical concentration ranges for these components. Target purity levels for the for recycled water are determined for each individual component based on NASA s required maximum contaminant levels for potable water Distillation processes are modeled separately and in tandem with air stripping to demonstrate the potential effectiveness and utility of these methods in recycling wastewater on the Moon. Optimum parameters such as reflux ratio, feed stage location, and processing rates are determined with respect to the power consumption of the process. Multistage distillation is evaluated for components in wastewater to determine the minimum number of stages necessary for each of 65 components in humidity condensate and urine wastewater mixed streams. Components of the wastewater streams are ranked by Henry s Law Constant and the suitability of air stripping in the purification of wastewater in terms of component removal is evaluated. Scaling factors for distillation and air stripping columns are presented to account for the difference in the lunar gravitation environment. Commercially available distillation and air stripping units which are considered suitable for Exploration Life Support

  10. Distillation and Air Stripping Designs for the Lunar Surface

    Science.gov (United States)

    Boul, Peter J.; Lange, Kevin E.; Conger, Bruce; Anderson, Molly

    2009-01-01

    Air stripping and distillation are two different gravity-based methods, which may be applied to the purification of wastewater on the lunar base. These gravity-based solutions to water processing are robust physical separation techniques, which may be advantageous to many other techniques for their simplicity in design and operation. The two techniques can be used in conjunction with each other to obtain high purity water. The components and feed compositions for modeling waste water streams are presented in conjunction with the Aspen property system for traditional stage distillation models and air stripping models. While the individual components for each of the waste streams will vary naturally within certain bounds, an analog model for waste water processing is suggested based on typical concentration ranges for these components. Target purity levels for the for recycled water are determined for each individual component based on NASA s required maximum contaminant levels for potable water Distillation processes are modeled separately and in tandem with air stripping to demonstrate the potential effectiveness and utility of these methods in recycling wastewater on the Moon. Optimum parameters such as reflux ratio, feed stage location, and processing rates are determined with respect to the power consumption of the process. Multistage distillation is evaluated for components in wastewater to determine the minimum number of stages necessary for each of 65 components in humidity condensate and urine wastewater mixed streams. Components of the wastewater streams are ranked by Henry s Law Constant and the suitability of air stripping in the purification of wastewater in terms of component removal is evaluated. Scaling factors for distillation and air stripping columns are presented to account for the difference in the lunar gravitation environment. Commercially available distillation and air stripping units which are considered suitable for Exploration Life Support

  11. Optimal design of irradiance redistribution guides for the National Renewable Energy Laboratory's high-flux solar furnace

    Science.gov (United States)

    Bortz, John C.; Shatz, Narkis E.; Lewandowski, Allan

    1995-08-01

    The National Renewable Energy Laboratory (NREL) has developed and operates the high-flux solar furnace (HFSF), a 10-kW solar concentrator used for research in solar energy applications. An application of ongoing interest is the heat-bonding of metallic foils to ceramic substrates, a process requiring a highly uniform irradiance distribution over a 10 by 10-cm target area, as well as a mean irradiance of at least 10 W/cm2, and a working distance of at least 10-cm from the optics. Science Applications International Corporation (SAIC) and NREL have developed designs for two reflective irradiance redistribtuion guides (IRGs) for use in conjunction with the HFSF, which provide significantly enhanced irradiance uniformity while exceeding the mean-irradiance and working-distance requirements. Irradiance- uniformity levels of 7.2% and 3.1% root-mean-square (RMS) deviation over the target area were achieved by the two IRG designs. The designs were generated using SAICs nonimaging concentrator synthesis code, which employs a global optimization procedure. The HFSF was modeled by means of an optical ray set produced by NREL's solar furnace code. The IRG designs are novel in that they feature re-entrant optics combined with the intentional use of ray paths having different nubmers of multiple reflections within a single reflective optical component in order to achieve the desired irradiance distribution.

  12. Design, fabrication, and characterization of metallic nanostructures for surface-enhanced Raman spectroscopy and plasmonic applications

    Science.gov (United States)

    Hao, Qingzhen

    Metal/dielectric nanostructures have the ability to sustain coherent electron oscillations known as surface plasmons. Due to their capability of localizing and guiding light in sub-wavelength metal nanostructures beyond diffraction limits, surface plasmon-based photonics, or “plasmonics” has opened new physical phenomena and lead to novel applications in metamaterials, optoelectronics, surface enhanced spectroscopy and biological sensing. This dissertation centers on design, fabrication, characterization of metallic nanostructures and their applications in surface-enhanced Raman spectroscopy (SERS) and actively tunable plasmonics. Metal-dielectric nanostructures are the building blocks for photonic metamaterials. One valuable design guideline for metamaterials is the Babinet’s principle, which governs the optical properties of complementary nanostructures. However, most complementary metamaterials are designed for the far infrared region or beyond, where the optical absorption of metal is small. We have developed a novel dual fabrication method, capable of simultaneously producing optically thin complementary structures. From experimental measurements and theoretical simulations, we showed that Babinet’s principle qualitatively holds in the visible region for the optically thin complements. The complementary structure is also a good platform to study subtle differences between nanoparticles and nanoholes in SERS (a surface sensitive technique, which can enhance the conventional Raman cross-section by 106˜108 fold, thus very useful for highly sensitive biochemical sensing). Through experimental measurement and theoretical analysis, we showed that the SERS enhancement spectrum (plot of SERS enhancement versus excitation wavelengths), dominated by local near-field, for nanoholes closely follows their far-field optical transmission spectrum. However, the enhancement spectrum for nanoparticles red-shifts significantly from their far-field optical extinction

  13. Study Report of Design Guide for Single Circular Cylinder in Axial Flow

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The vibration of a flexible cylinder in axial flow is random, so the quantities of interests are the root-mean-square value of the response and the amplitude distribution. This design guideline presents a relationship for calculating the

  14. Technical Support Document: Development of the Advanced Energy Design Guide for Grocery Stores--50% Energy Savings

    Energy Technology Data Exchange (ETDEWEB)

    Hale, E. T.; Macumber, D. L.; Long, N. L.; Griffith, B. T.; Benne, K. S.; Pless, S. D.; Torcellini, P. A.

    2008-09-01

    This report provides recommendations that architects, designers, contractors, developers, owners, and lessees of grocery store buildings can use to achieve whole-building energy savings of at least 50% over ASHRAE Standard 90.1-2004.

  15. Fibre optic surface plasmon resonance sensor system designed for smartphones.

    Science.gov (United States)

    Bremer, Kort; Roth, Bernhard

    2015-06-29

    A fibre optic surface plasmon resonance (SPR) sensor system for smartphones is reported, for the first time. The sensor was fabricated by using an easy-to-implement silver coating technique and by polishing both ends of a 400 µm optical fibre to obtain 45° end-faces. For excitation and interrogation of the SPR sensor system the flash-light and camera at the back side of the smartphone were employed, respectively. Consequently, no external electrical components are required for the operation of the sensor system developed. In a first application example a refractive index sensor was realised. The performance of the SPR sensor system was demonstrated by using different volume concentrations of glycerol solution. A sensitivity of 5.96·10(-4) refractive index units (RIU)/pixel was obtained for a refractive index (RI) range from 1.33 to 1.36. In future implementations the reported sensor system could be integrated in a cover of a smartphone or used as a low-cost, portable point-of-care diagnostic platform. Consequently it offers the potential of monitoring a large variety of environmental or point-of-care parameters in combination with smartphones.

  16. Energy-efficient HVAC design an essential guide for sustainable building

    CERN Document Server

    Khazaii, Javad

    2014-01-01

    This book provides readers with essential knowledge enabling the successful design of today's new energy efficient HVAC systems. The author introduces important concepts such as Knowledge Categorization, Performance Based Design Standards, and Quantification of Uncertainty in Energy Modeling for Buildings. Pivotal topics that all HVAC and architectural engineers must master in order to navigate the green building renaissance are given focused attention, including the role of renewables, air quality, automatic controls, and thermal comfort. Relevant ASHRAE standards, as well as sustainability s

  17. Some recent developments in surface and interface design for photocatalytic and electrocatalytic hybrid structures.

    Science.gov (United States)

    Bai, Song; Xiong, Yujie

    2015-06-28

    The surface and interface are considered as the crucial features that can be engineered to improve the performance of catalysts. The great advancements in both controlled syntheses and catalytic mechanism studies have paved the way for the rational surface and interface design of catalysts. In this feature article, we overview our recent progress in surface and interface design for well-defined hybrid structures mainly toward the photocatalytic and electrocatalytic applications in which charge carriers play an important role. First, we outline the surface parameters of components including exposed facets, compositions, surface areas and crystal phases that have been tailored toward higher surface activation abilities for electrocatalytic and photocatalytic reactions. Second, we summarize the designing rules for the interface between two components to favor the charge transfer for photocatalytic reactions on the surface. Furthermore, we outline the synergistic effects on photocatalysis and electrocatalysis through the simultaneous control of the surface and the interface, which can also be extended to enhance other catalytic reactions (e.g., CO oxidation). Finally, we discuss the challenges and opportunities for further development of surface and interface design toward catalytic performance tuning.

  18. Expert Guide

    DEFF Research Database (Denmark)

    Heiselberg, Per

    This guide summarizes the work of Subtask B of IEA-ECBCS Annex 44 “Integrating Environmentally Responsive Elements in Buildings” and is based on the contributions from the participating countries. The publication is an official Annex report. With a focus on innovative building concepts...... that dynamically respond to changes in climate and user demands, the report describes building concepts, design methods and tools that have been tested in theory and practice in buildings around the world. This guide is aimed at designers and consultants and describes the principles of responsive building concepts...

  19. Optical design and laser ablation of surface textures: demonstrating total internal reflection

    Science.gov (United States)

    Gommans, Hans; Booij, Silvia; Pijlman, Fetze; Krijn, Marcel; de Zwart, Siebe; Sepkhanov, Ruslan; Beaumont, Dave; van der Schaft, Hans; Sanders, Rene

    2015-09-01

    In lighting applications key drivers for optical design of surface textures are integration of optical elements, the disentanglement of optical functionality and appearance and late stage configuration. We investigated excimer laser ablation as a mastering technology for micro textured surfaces, where we targeted an increase in correspondence between surface design and ablated surface for high aspect ratio structures. To achieve this we have improved the photo mask design using a heuristic algorithm that corrects for the angular dependence of the ablation process and the loss of image resolution at ablation depths that exceed the depth of field. Using this approach we have been able to demonstrate close correspondence between designed and ablated facet structures up to 75° inclination at 75 μm depth. These facet design parameters allow for total internal reflection (TIR) as a means of beam deflection which is demonstrated in a range of mono shaped cone arrays in hexagonal tessellation. BSDF analysis was used to characterize the narrow TIR deflection beams that matched the peak positions of the design down to 28° apex. In addition, a single surface TIR-Fresnel lens design with focal distance 5 mm has been manufactured using this photo mask design algorithm and beam collimation up to 12° beam angle and 32° field angle is shown. These outcomes demonstrate that the laser ablation process intrinsically yields sufficient small dispersion in structure and fillet radii for lighting applications.

  20. Monolithic precolumns as efficient tools for guiding the design of nanoparticulate drug-delivery formulations.

    Science.gov (United States)

    Gatschelhofer, Christina; Prasch, Agnes; Buchmeiser, Michael R; Zimmer, Andreas; Wernig, Karin; Griesbacher, Martin; Pieber, Thomas R; Sinner, Frank M

    2012-09-01

    The development of nanomedicines for improved diagnosis and treatment of diseases is pushing current analytical methods to their limits. More efficient, quantitative high-throughput screening methods are needed to guide the optimization of promising nanoparticulate drug delivery formulations. In response to this need, we present herein a novel approach using monolithic separation media. The unique porosity of our capillary monolithic precolumns allows the direct injection and online removal of protamine-oligonucleotide nanoparticles ("proticles") without column clogging, thus avoiding the need for time-consuming off-line sample workup. Furthermore, ring-opening metathesis polymerization (ROMP)-derived monoliths show equivalent preconcentration efficiency for the target drug vasoactive intestinal peptide (VIP) as conventional particle-packed precolumns. The performance of the ROMP-derived monolithic precolumns was constant over at least 100 injections of crude proticle-containing and 300 injections of highly acidic samples. Applying a validated LC-MS/MS capillary monolithic column switching method, we demonstrate the rapid determination of both drug load and in vitro drug release kinetics of proticles within the critical first 2 h and investigate the stability of VIP-loaded proticles in aqueous storage medium intended for inhalation therapy.