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Sample records for surface-modified counterparts reveal

  1. Molecular insights of the first gastropod TLR counterpart from disk abalone (Haliotis discus discus), revealing its transcriptional modulation under pathogenic stress.

    Science.gov (United States)

    Elvitigala, Don Anushka Sandaruwan; Premachandra, H K A; Whang, Ilson; Nam, Bo-Hye; Lee, Jehee

    2013-08-01

    Toll-like receptors (TLRs) are well-characterized pattern recognition receptors of innate immunity, known to induce immune responses against the pathogens by interacting with evolutionarily conserved pathogen-associated molecular patterns (PAMPs). In this study, a novel TLR homolog from disk abalone (Haliotis discus discus) was identified and characterized at molecular level. The open reading frame (ORF) of AbTLR is 3804 bp in length and encodes a 1268 amino acid peptide with a calculated molecular mass of 143.5 kDa. The deduced protein shows typical TLR domain architecture, with leucine rich repeats (LRR) and the toll-interleukin receptor (TIR) domain. Phylogenetic analysis revealed a close evolutionary relationship for AbTLR to its invertebrate counterparts, with close clustering to the molluscan homologs. Quantitative real-time PCR detected ubiquitous transcription of AbTLR in healthy tissues, but with highest levels in hemocytes. Differential transcriptional modulation of AbTLR was observed in abalone hemocytes and gills upon immune challenge, whereby Vibrio parahaemolyticus and purified lipopolysaccharide (LPS) enhanced the transcript level prominently. In addition, the viral hemorrhagic septicemia virus induced AbTLR transcription in hemocytes and gills, representing the first evidence of viral-induced immune response in mollusks to date. Collectively, our findings support a putative role for AbTLR in abalone antiviral and antibacterial defense. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. XMM-Newton Observations Reveal the X-ray Counterpart of the Very-high-energy gamma-ray Source HESS J1640-465

    Energy Technology Data Exchange (ETDEWEB)

    Funk, S.; Hinton, J.A.; Puhlhofer, G.; Aharonian, F.A.; Hofmann, W.; Reimer, O.; Wagner, S.; /KIPAC, Menlo Park /Heidelberg, Max Planck Inst. /Leeds U. /Dublin Inst. /Stanford U., HEPL; Funk, S.; Hinton, J.A.; Puehlhofer, G.; Aharonian, F.A.; Hofmann, W.; Reimer, O.; Wagner, S.

    2007-03-05

    We present X-ray observations of the as of yet unidentified very high-energy (VHE) {gamma}-ray source HESS J1640-465 with the aim of establishing a counterpart of this source in the keV energy range, and identifying the mechanism responsible for the VHE emission. The 21.8 ksec XMM-Newton observation of HESS J1640-465 in September 2005 represents a significant improvement in sensitivity and angular resolution over previous ASCA studies in this region. These new data show a hard-spectrum X-ray emitting object at the centroid of the H.E.S.S. source, within the shell of the radio Supernova Remnant (SNR) G338.3-0.0. This object is consistent with the position and flux previously measured by both ASCA and Swift-XRT but is now shown to be significantly extended. We argue that this object is very likely the counterpart to HESS J1640-465 and that both objects may represent the Pulsar Wind Nebula of an as of yet undiscovered pulsar associated with G338.3-0.0.

  3. Porous surface modified bioactive bone cement for enhanced bone bonding.

    Directory of Open Access Journals (Sweden)

    Qiang He

    Full Text Available Polymethylmethacrylate bone cement cannot provide an adhesive chemical bonding to form a stable cement-bone interface. Bioactive bone cements show bone bonding ability, but their clinical application is limited because bone resorption is observed after implantation. Porous polymethylmethacrylate can be achieved with the addition of carboxymethylcellulose, alginate and gelatin microparticles to promote bone ingrowth, but the mechanical properties are too low to be used in orthopedic applications. Bone ingrowth into cement could decrease the possibility of bone resorption and promote the formation of a stable interface. However, scarce literature is reported on bioactive bone cements that allow bone ingrowth. In this paper, we reported a porous surface modified bioactive bone cement with desired mechanical properties, which could allow for bone ingrowth.The porous surface modified bioactive bone cement was evaluated to determine its handling characteristics, mechanical properties and behavior in a simulated body fluid. The in vitro cellular responses of the samples were also investigated in terms of cell attachment, proliferation, and osteoblastic differentiation. Furthermore, bone ingrowth was examined in a rabbit femoral condyle defect model by using micro-CT imaging and histological analysis. The strength of the implant-bone interface was also investigated by push-out tests.The modified bone cement with a low content of bioactive fillers resulted in proper handling characteristics and adequate mechanical properties, but slightly affected its bioactivity. Moreover, the degree of attachment, proliferation and osteogenic differentiation of preosteoblast cells was also increased. The results of the push-out test revealed that higher interfacial bonding strength was achieved with the modified bone cement because of the formation of the apatite layer and the osseointegration after implantation in the bony defect.Our findings suggested a new bioactive

  4. Physicochemical characterization of E. coli-derived human serum albumin and its comparison with the human plasma counterpart reveals it as a promising biosimilar.

    Science.gov (United States)

    Sharma, Ashima; Chaudhuri, Tapan K

    2018-03-07

    Human serum albumin one of the most demanded proteins possess an array of clinical and biotechnological applications. Currently, the prime source for HSA production is the human blood which possesses the risk of pathogen contamination and is limited. Thus, there exists an indispensable need to promote non-animal derived HSA production. In the present work, we have exploited the opportunity and promoted the preparation of pathogen-free rHSA from the E. coli host which is blessed with numerous advantages like scalability, cost-effectiveness etc. Upon overcoming the difficulties to produce functional rHSA in E. coli, through engineering the biological system of protein folding in the cell, the E. coli-derived rHSA has been purified to homogeneity. Its detailed physicochemical characterization has been performed, by monitoring its conformational properties, secondary and tertiary structure elements, surface properties, ligand binding properties, stability issues etc. These parameters of the recombinant protein have been compared with the naturally occurring protein from the human source. The outcome of the comparison reveals that the recombinant protein resembles exactly the same as the natural one. Hence, we propose and promote that the E. coli-derived rHSA is an ideal biosimilar for human blood plasma-derived serum albumin. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. Surface-modified magnetic nanoparticles for cell labeling

    Czech Academy of Sciences Publication Activity Database

    Zasońska, Beata Anna; Patsula, Vitalii; Stoika, R.; Horák, Daniel

    2014-01-01

    Roč. 13, č. 4 (2014), s. 63-73 ISSN 2305-7815 R&D Projects: GA MŠk(CZ) LH14318 Institutional support: RVO:61389013 Keywords : magnetic nanoparticles * surface-modified * cell labeling Subject RIV: CD - Macromolecular Chemistry

  6. Implication of surface modified NZVI particle retention in the porous ...

    Indian Academy of Sciences (India)

    Retention of surface-modified nanoscale zero-valent iron (NZVI) particles in the porous media near the point of injection has been reported in the recent studies. Retention of excess particles in porous media can alter the media properties. The main objectives of this study are, therefore, to evaluate the effect of particle ...

  7. Efficiency of surface modified Ti coated with copper nanoparticles to ...

    Indian Academy of Sciences (India)

    various fields like medical instruments and devices, water treatment and food processing. For better utilization of antimicrobial activity the metal nanoparticles may be com- bined with polymers to form composites [23]. Our pre- vious study also proved the anti-biofouling property of surface modified Ti coated with silver ...

  8. Corrosion resistance of surface modified nickel titanium archwires.

    Science.gov (United States)

    Krishnan, Manu; Seema, Saraswathy; Kumar, A Vinod; Varthini, N Parvatha; Sukumaran, Kalathil; Pawar, Vasant R; Arora, Vimal

    2014-03-01

    To compare the corrosion behavior of commercially available surface modified nickel titanium (NiTi) arch wires with respect to a conventional NiTi and to evaluate its association with surface characteristics. Five types of surface modified arch wires and a conventional NiTi arch wire, all from different manufacturers, were evaluated for their corrosion resistance from breakdown potential in an anodic polarization scan in Ringer's solution. Surface characteristics were determined from scanning electron microscopy, atomic force microscopy, and energy dispersive analysis. One-way analysis of variance and post hoc Duncan's multiple range tests were used to evaluate statistical significance. Surface modified NiTi wires showed significant improvement in corrosion resistance and reduction in surface roughness values. Breakdown potentials increased in the order of group 6 (conventional; 204 mV) corrosion resistance and decreasing surface roughness. However, neither factor could maintain a direct, one-to-one relationship. It meant that the type and nature of coating material can effectively influence the anticorrosive features of NiTi wires, compared with its surface roughness values.

  9. Surface-modified nanocrystalline ceramics for drug delivery applications.

    Science.gov (United States)

    Kossovsky, N; Gelman, A; Sponsler, E E; Hnatyszyn, H J; Rajguru, S; Torres, M; Pham, M; Crowder, J; Zemanovich, J; Chung, A

    1994-12-01

    Drug delivery systems comprised of various types of carriers have long been the object of pharmacological investigation. The search has been stimulated by the belief that carriers will lead to reduced drug toxicity, dosage requirements, enhanced cellular targeting and improved shelf-life. Among the carriers investigated are complex polymeric carbohydrates, synthetic proteins and liposomal structures. For the past four years, we have been experimenting with a radically new class of carriers comprised of surface-modified nanocrystalline ceramics. While the ceramics provide the structural stability of a largely immutable solid, the surface modification creates a glassy molecular stabilization film to which pharmacological agents may be bound non-covalently from an aqueous phase with minimal structural denaturation. As a consequence of maintained structural integrity and owing to concentration effects afforded by the surfaces of the nanocrystalline materials, drug activity following surface immobilization is preserved. We have used successfully surface-modified nanocrystalline ceramics to deliver viral antigens for the purpose of evoking an immune response, oxygenated haemoglobin for cell respiration and insulin for carbohydrate metabolism. The theoretical principles, technical details and experimental results are reviewed. Surface-modified nanocrystalline materials offer an exciting new approach to the well-recognized challenges of drug delivery.

  10. Optimization of Phospholipase A1 Immobilization on Plasma Surface Modified Chitosan Nanofibrous Mat

    Directory of Open Access Journals (Sweden)

    Zahra Beig Mohammadi

    2016-01-01

    Full Text Available Phospholipase A1 is known as an effective catalyst for hydrolysis of various phospholipids in enzymatic vegetable oil degumming. Immobilization is one of the most efficient strategies to improve its activity, recovery and functional properties. In this study, chitosan-co-polyethylene oxide (90:10 nanofibrous mat was successfully fabricated and modified with atmospheric plasma at different times (2, 6 and 10 min to interact with enzyme molecules. Scanning electron microscopy images revealed that the membranes retained uniform nanofibrous and open porous structures before and after the treatment. PLA1 was successfully immobilized onto the membrane surfaces via covalent bonds with the functional groups of chitosan nanofibrous mat. Response surface methodology was used to optimize the immobilization conditions for reaching the maximum immobilization efficiency. Enzyme concentration, pH, and immobilization time were found to be significant key factors. Under optimum conditions (5.03 h, pH 5.63, and enzyme dosage 654.36 UI, the atmospheric plasma surface modified chitosan nanofibers reached the highest immobilization efficiency (78.50%. Fourier transform infrared spectroscopy of the control and plasma surface-modified chitosan nanofibers revealed the functional groups of nanofibers and their reaction with the enzyme. The results indicated that surface modification by atmospheric plasma induced an increase in PLA1 loading on the membrane surfaces.

  11. Synthesis and Evaluation of Zeolite Surface-Modified Perlite

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    Kasai Makoto

    2017-01-01

    Full Text Available Perlite is volcanic glass mainly composed of amorphous aluminum silicate, mainly composed SiO2 and Al2O3 with less impurities such as heavy metals. Amorphous (glassy perlite is used in lightweight aggregate and insulation. In addition, it has also been used as a filter aid by grinding the expanded perlite. However, it has not been used as environmental cleanup materials, because the ion exchange capacity of the perlite is very low. In this study, we tried to synthesize the hybrid filter aid with chemical adsorption capacity by synthesizing the zeolite on the surface of the perlite. As a result, by using the hydrothermal synthesis method, zeolite surface modified perlite was synthesized in which the LTA type zeolites were generated on the surface of the perlite.

  12. Nonleaching antimicrobial films prepared from surface-modified microfibrillated cellulose.

    Science.gov (United States)

    Andresen, Martin; Stenstad, Per; Møretrø, Trond; Langsrud, Solveig; Syverud, Kristin; Johansson, Leena-Sisko; Stenius, Per

    2007-07-01

    We have prepared potentially permanent antimicrobial films based on surface-modified microfibrillated cellulose (MFC). MFC, obtained by disintegration of bleached softwood sulfite pulp in a homogenizer, was grafted with the quaternary ammonium compound octadecyldimethyl(3-trimethoxysilylpropyl)ammonium chloride (ODDMAC) by a simple adsorption-curing process. Films prepared from the ODDMAC-modified MFC were characterized by Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) and tested for antibacterial activity against the Gram-positive bacterium Staphylococcus aureus and the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa. The films showed substantial antibacterial capacity even at very low concentrations of antimicrobial agent immobilized on the surface. A zone of inhibition test demonstrated that no ODDMAC diffused into the surroundings, verifying that the films were indeed of the nonleaching type.

  13. Osteoblast cell response to surface-modified carbon nanotubes

    International Nuclear Information System (INIS)

    Zhang Faming; Weidmann, Arne; Nebe, J. Barbara; Burkel, Eberhard

    2012-01-01

    In order to investigate the interaction of cells with modified multi-walled carbon nanotubes (MWCNTs) for their potential biomedical applications, the MWCNTs were chemically modified with carboxylic acid groups (–COOH), polyvinyl alcohol (PVA) polymer and biomimetic apatite on their surfaces. Additionally, human osteoblast MG-63 cells were cultured in the presence of the surface-modified MWCNTs. The metabolic activities of osteoblastic cells, cell proliferation properties, as well as cell morphology were studied. The surface modification of MWCNTs with biomimetic apatite exhibited a significant increase in the cell viability of osteoblasts, up to 67.23%. In the proliferation phases, there were many more cells in the biomimetic apatite-modified MWCNT samples than in the MWCNTs–COOH. There were no obvious changes in cell morphology in osteoblastic MG-63 cells cultured in the presence of these chemically-modified MWCNTs. The surface modification of MWCNTs with apatite achieves an effective enhancement of their biocompatibility.

  14. ELECTROCATALYSIS ON SURFACES MODIFIED BY METAL MONOLAYERS DEPOSITED AT UNDERPOTENTIALS.

    Energy Technology Data Exchange (ETDEWEB)

    ADZIC,R.

    2000-12-01

    The remarkable catalytic properties of electrode surfaces modified by monolayer amounts of metal adatoms obtained by underpotential deposition (UPD) have been the subject of a large number of studies during the last couple of decades. This interest stems from the possibility of implementing strictly surface modifications of electrocatalysts in an elegant, well-controlled way, and these bi-metallic surfaces can serve as models for the design of new catalysts. In addition, some of these systems may have potential for practical applications. The UPD of metals, which in general involves the deposition of up to a monolayer of metal on a foreign substrate at potentials positive to the reversible thermodynamic potential, facilitates this type of surface modification, which can be performed repeatedly by potential control. Recent studies of these surfaces and their catalytic properties by new in situ surface structure sensitive techniques have greatly improved the understanding of these systems.

  15. Improved Composites Using Crosslinked, Surface-Modified Carbon Nanotube Materials

    Science.gov (United States)

    Baker, James Stewart

    2014-01-01

    Individual carbon nanotubes (CNTs) exhibit exceptional tensile strength and stiffness; however, these properties have not translated well to the macroscopic scale. Premature failure of bulk CNT materials under tensile loading occurs due to the relatively weak frictional forces between adjacent CNTs, leading to poor load transfer through the material. When used in polymer matrix composites (PMCs), the weak nanotube-matrix interaction leads to the CNTs providing less than optimal reinforcement.Our group is examining the use of covalent crosslinking and surface modification as a means to improve the tensile properties of PMCs containing carbon nanotubes. Sheet material comprised of unaligned multi-walled carbon nanotubes (MWCNT) was used as a drop-in replacement for carbon fiber in the composites. A variety of post-processing methods have been examined for covalently crosslinking the CNTs to overcome the weak inter-nanotube shear interactions, resulting in improved tensile strength and modulus for the bulk sheet material. Residual functional groups from the crosslinking chemistry may have the added benefit of improving the nanotube-matrix interaction. Composites prepared using these crosslinked, surface-modified nanotube sheet materials exhibit superior tensile properties to composites using the as received CNT sheet material.

  16. Interaction of surface-modified silica nanoparticles with clay minerals

    Directory of Open Access Journals (Sweden)

    Cigdem Omurlu

    2016-05-01

    Full Text Available Abstract In this study, the adsorption of 5-nm silica nanoparticles onto montmorillonite and illite is investigated. The effect of surface functionalization was evaluated for four different surfaces: unmodified, surface-modified with anionic (sulfonate, cationic (quaternary ammonium (quat, and nonionic (polyethylene glycol (PEG surfactant. We employed ultraviolet–visible spectroscopy to determine the concentration of adsorbed nanoparticles in conditions that are likely to be found in subsurface reservoir environments. PEG-coated and quat/PEG-coated silica nanoparticles were found to significantly adsorb onto the clay surfaces, and the effects of electrolyte type (NaCl, KCl and concentration, nanoparticle concentration, pH, temperature, and clay type on PEG-coated nanoparticle adsorption were studied. The type and concentration of electrolytes were found to influence the degree of adsorption, suggesting a relationship between the interlayer spacing of the clay and the adsorption ability of the nanoparticles. Under the experimental conditions reported in this paper, the isotherms for nanoparticle adsorption onto montmorillonite at 25 °C indicate that adsorption occurs less readily as the nanoparticle concentration increases.

  17. Dithiocarbamate Self-Assembled Monolayers as Efficient Surface Modifiers for Low Work Function Noble Metals

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Dominik; Schäfer, Tobias; Schulz, Philip; Jung, Sebastian; Rittich, Julia; Mokros, Daniel; Segger, Ingolf; Maercks, Franziska; Effertz, Christian; Mazzarello, Riccardo; Wuttig, Matthias

    2016-09-06

    Tuning the work function of the electrode is one of the crucial steps to improve charge extraction in organic electronic devices. Here, we show that N,N-dialkyl dithiocarbamates (DTC) can be effectively employed to produce low work function noble metal electrodes. Work functions between 3.1 and 3.5 eV are observed for all metals investigated (Cu, Ag, and Au). Ultraviolet photoemission spectroscopy (UPS) reveals a maximum decrease in work function by 2.1 eV as compared to the bare metal surface. Electronic structure calculations elucidate how the complex interplay between intrinsic dipoles and dipoles induced by bond formation generates such large work function shifts. Subsequently, we quantify the improvement in contact resistance of organic thin film transistor devices with DTC coated source and drain electrodes. These findings demonstrate that DTC molecules can be employed as universal surface modifiers to produce stable electrodes for electron injection in high performance hybrid organic optoelectronics.

  18. Adhesion of Aeromonas hydrophila to Glass Surfaces Modified with Organosilanes

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    Dorota Kregiel

    2013-01-01

    Full Text Available The aim of this research is to study the adhesive properties of Aeromonas hydrophila to glass surfaces modified using four silanes with different reactive groups, namely (3-glycidoxypropyl diethoxysilane, (3-N,N-dimethyl-3-N-n hexadecylammoniopropyltrimethoxysilane chloride, (3-N,N,N-triethanolammoniopropyltrimethoxysilane chloride, and (3-N,N-dimethyl- 3-N-n-octylammoniopropyltrimethoxysilane chloride. The strain used in the study was A. hydrophila LOCK0968, isolated from the unchlorinated communal water distribution system in Poland. The effect of glass modification after chemical treatment was analyzed using surface tension measurement. The adhesive properties of the bacteria were studied in a water environment with a low concentration of organic compounds, using luminometric and microscopic methods. Additionally, the viability of the adherent bacterial cells was evaluated by counting the colony-forming units. The presence of active compounds in the culture medium after incubation with a modified carrier was verified using the Kirby- -Bauer method. Half of the chemically modified glass surfaces exhibited better characteristics in comparison with native glass. Among the examined modifying agents, (3-N,N,N-triethanolammoniopropyl trimethoxysilane chloride and (3-N,N-dimethyl-3-N-n octylammoniopropyl trimethoxysilane chloride showed the best antiadhesive and antibacterial properties. The most effective glass modification, with (3-N,N,N triethanolammoniopropyltrimethoxysilane chloride, was able to reduce the bacterial cell count by more than three orders of magnitude. The carriers had no significant effect on the viability of the free bacterial cells in the culture medium. Therefore, it can be said that the modified glass surface alone accounts for the antibacterial activity of the active organosilanes.

  19. SURFACE-MODIFIED COALS FOR ENHANCED CATALYST DISPERSION AND LIQUEFACTION

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Yaw D. Yeboah

    1999-09-01

    This is the final report of the Department of Energy Sponsored project DE-FGF22-95PC95229 entitled, surface modified coals for enhanced catalyst dispersion and liquefaction. The aims of the study were to enhance catalyst loading and dispersion in coal for improved liquefaction by preadsorption of surfactants and catalysts on the coal and to train and educate minority scientists in catalysts and separation science. Illinois No. 6 Coal (DEC-24) was selected for the study. The surfactants investigated included dodecyl dimethyl ethyl ammonium bromide (DDAB), a cationic surfactant, sodium dodecyl sulfate, an anionic surfactant, and Triton x-100, a neutral surfactant. Ammonium molybdate tetrahydrate was used as the molybdenum catalyst precursor. Zeta potential, BET, FTIR, AFM, UV-Vis and luminescence intensity measurements were undertaken to assess the surface properties and the liquefaction activities of the coal. The parent coal had a net negative surface charge over the pH range 2-12. However, in the presence of DDAB the negativity of the surface charge decreased. At higher concentrations of DDAB, a positive surface charge resulted. In contrast to the effect of DDAB, the zeta potential of the coal became more negative than the parent coal in the presence of SDS. Adsorption of Triton reduced the net negative charge density of the coal samples. The measured surface area of the coal surface was about 30 m{sup 2}/g compared to 77m{sup 2}/g after being washed with deionized water. Addition of the surfactants decreased the surface area of the samples. Adsorption of the molybdenum catalyst increased the surface area of the coal sample. The adsorption of molybdenum on the coal was significantly promoted by preadsorption of DDAB and SDS. Molybdenum adsorption showed that, over a wide range of concentrations and pH values, the DDAB treated coal adsorbed a higher amount of molybdenum than the samples treated with SDS. The infrared spectroscopy (FTIR) and the atomic force

  20. Quantum experiments without classical counterparts

    International Nuclear Information System (INIS)

    Pavicic, M.

    2005-01-01

    Full text: We present a generalized and exhaustive method of finding the directions of the quantization axes of the measured eigenstates within experiments which have no classical counterparts. The method relies on a constructive and exhaustive definition of sets of such directions (which we call Kochen-Specker vectors) in a Hilbert space of any dimension as well as of all the remaining vectors of the space. Kochen-Specker vectors are elements of any set of orthonormal states, i.e., vectors in n-dim Hilbert space, Hn, n > 2 to which it is impossible to assign 1s and 0s in such a way that no two mutually orthogonal vectors from the set are both assigned 1 and that not all mutually orthogonal vectors are assigned 0. Our constructive definition of such Kochen-Specker vectors is based on algorithms that generate MMP diagrams corresponding to blocks of orthogonal vectors in Rn, on algorithms that single out those diagrams on which algebraic to 0-1 states cannot be defined, and on algorithms that solve nonlinear equations describing the orthogonalities of the vectors by means of statistically polynomially complex interval analysis and self-teaching programs. The algorithms are limited neither by the number of dimensions nor by the number of vectors. To demonstrate the power of the algorithms, all 4-dim KS vector systems containing up to 24 vectors were generated and described, all 3-dim vector systems containing up to 30 vectors were scanned, and several general properties of KS vectors were found. (author)

  1. Development of a surface modified silicone-keratoprosthesis with scleral fixation.

    Science.gov (United States)

    von Fischern, T; Langefeld, S; Yuan, L; Völcker, N; Reim, M; Kirchhof, B; Schrage, N F

    1998-01-01

    Many attempts have been made to create artificial corneas. The keratoprostheses currently available do not allow measurements of the intraocular pressure (IOP) and restrict the visual field. The main problem is extrusion due to an insufficient connection between implant and surrounding tissue. It is our aim to create a flexible keratoprosthesis with a wide field optic allowing measurements of the IOP. Surface modification will improve cell adhesion and therefore stability between implant and tissue. The keratoprosthesis is made of silicone rubber. The optical zone is 11 mm in diameter with a thickness of 0.3 mm. The surface modified haptic consists of a scleral rim and 8 branches for scleral fixation. Optical and mechanical qualities were tested by tensile tests, spectrophotometry and topography. A method to produce one-piece silicone keratoprostheses was established. Submicron lathing of the mould led to an excellent optical quality. Spectrophotometry showed high degree of visible and ultraviolet light transmission of the silicone. Mechanical tests revealed high tensile strength and elongation at break which were not impaired by surface modification. The production of a flexible silicone keratoprosthesis with high optical and mechanical properties was accomplished, with possible use as both permanent and temporary keratoprosthesis.

  2. Improvement of in vitro corrosion and cytocompatibility of biodegradable Fe surface modified by Zn ion implantation

    Science.gov (United States)

    Wang, Henan; Zheng, Yang; Li, Yan; Jiang, Chengbao

    2017-05-01

    Pure Fe was surface-modified by Zn ion implantation to improve the biodegradable behavior and cytocompatibility. Surface topography, chemical composition, corrosion resistance and cytocompatibility were investigated. Atomic force microscopy, auger electron spectroscopy and X-ray photoelectron spectroscopy results showed that Zn was implanted into the surface of pure Fe in the depth of 40-60 nm and Fe2O3/ZnO oxides were formed on the outmost surface. Electrochemical measurements and immersion tests revealed an improved degradable behavior for the Zn-implanted Fe samples. An approximately 12% reduction in the corrosion potential (Ecorr) and a 10-fold increase in the corrosion current density (icorr) were obtained after Zn ion implantation with a moderate incident ion dose, which was attributed to the enhanced pitting corrosion. The surface free energy of pure Fe was decreased by Zn ion implantation. The results of direct cell culture indicated that the short-term (4 h) cytocompatibility of MC3T3-E1 cells was promoted by the implanted Zn on the surface.

  3. Effect of surface modified TiO2 nanoparticles on thermal, barrier and mechanical properties of long oil alkyd resin-based coatings

    Directory of Open Access Journals (Sweden)

    T. S. Radoman

    2015-10-01

    Full Text Available Novel soy alkyd-based nanocomposites (NCs were prepared using TiO2 nanoparticles (NPs surface modified with different gallates, and for the first time with imine obtained from 3,4-dihydroxybenzaldehyde and oleylamine (DHBAOA. Unmodified and surface modified anatase TiO2 NPs were characterized by transmission electron microscopy (TEM, X-ray diffraction (XRD, Fourier transform infrared spectroscopy (FTIR and ultraviolet-visible (UV-Vis spectroscopy, while the amount of adsorbed ligands was calculated from thermogravimetric analysis (TGA results. Surface modification of TiO2 NPs was confirmed by FTIR and UV-Vis spectra. The influence of the TiO2 surface modification on the dispersion of TiO2 NPs in alkyd resin, thermal, barrier and mechanical properties and chemical resistance of alkyd resin/TiO2 NC coatings was investigated. The obtained results revealed that glass transition temperature of all investigated NCs is lower than for pure resin, that the presence of TiO2 NPs surface modified with gallates had no significant influence on the thermooxidative stability of alkyd resin, while TiO2-DHBAOA NPs slightly improved alkyd resin thermooxidative stability. Also, the presence of surface modified TiO2 NPs improved barrier properties, increased stress and strain at break and hardness and chemical resistance and decreased modulus of elasticity and abrasion resistance of alkyd resin.

  4. An investigation of the electrochemical action of the epoxy zinc-rich coatings containing surface modified aluminum nanoparticle

    Energy Technology Data Exchange (ETDEWEB)

    Jalili, M. [Nanomaterials and Nanocoatings Department, Institute for Color Science and Technology (ICST), PO 16765-654, Tehran (Iran, Islamic Republic of); Surface Coatings and Corrosion Department, Institute for Color Science and Technology (ICST), PO 16765-654, Tehran (Iran, Islamic Republic of); Rostami, M. [Nanomaterials and Nanocoatings Department, Institute for Color Science and Technology (ICST), PO 16765-654, Tehran (Iran, Islamic Republic of); Ramezanzadeh, B., E-mail: ramezanzadeh-bh@icrc.ac.ir [Surface Coatings and Corrosion Department, Institute for Color Science and Technology (ICST), PO 16765-654, Tehran (Iran, Islamic Republic of)

    2015-02-15

    Highlights: • Aluminum nanoparticle was modified with amino trimethylene phosphonic acid. • 2 wt% of zinc dust in zinc-rich paint was substituted by aluminum nanoparticles. • Surface modified aluminum nanoparticle improved the cathodic period of protection. • Aluminum nanoparticles enhanced the corrosion protection of the zinc-rich coating. - Abstract: Aluminum nanoparticle was modified with amino trimethylene phosphonic acid (ATMP). The surface characterization of the nanoparticles was done by X-ray photo electron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) and thermal gravimetric analysis. The influence of the replacement of 2 wt% of zinc dust in the standard zinc-rich epoxy coating by nanoparticles on the electrochemical action of the coating was studied by electrochemical impedance spectroscopy (EIS) and salt spray tests. The morphology and phase composition of the zinc rich paints were evaluated by X-ray diffraction (XRD) and filed-emission scanning electron microscopy (FE-SEM). Results showed that the ATMP molecules successfully adsorbed on the surface of Al nanoparticles. Results obtained from salt spray and electrochemical measurements revealed that the addition of surface modified nanoparticles to the zinc rich coating enhanced its galvanic action and corrosion protection properties.

  5. An investigation of the electrochemical action of the epoxy zinc-rich coatings containing surface modified aluminum nanoparticle

    International Nuclear Information System (INIS)

    Jalili, M.; Rostami, M.; Ramezanzadeh, B.

    2015-01-01

    Highlights: • Aluminum nanoparticle was modified with amino trimethylene phosphonic acid. • 2 wt% of zinc dust in zinc-rich paint was substituted by aluminum nanoparticles. • Surface modified aluminum nanoparticle improved the cathodic period of protection. • Aluminum nanoparticles enhanced the corrosion protection of the zinc-rich coating. - Abstract: Aluminum nanoparticle was modified with amino trimethylene phosphonic acid (ATMP). The surface characterization of the nanoparticles was done by X-ray photo electron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) and thermal gravimetric analysis. The influence of the replacement of 2 wt% of zinc dust in the standard zinc-rich epoxy coating by nanoparticles on the electrochemical action of the coating was studied by electrochemical impedance spectroscopy (EIS) and salt spray tests. The morphology and phase composition of the zinc rich paints were evaluated by X-ray diffraction (XRD) and filed-emission scanning electron microscopy (FE-SEM). Results showed that the ATMP molecules successfully adsorbed on the surface of Al nanoparticles. Results obtained from salt spray and electrochemical measurements revealed that the addition of surface modified nanoparticles to the zinc rich coating enhanced its galvanic action and corrosion protection properties

  6. EXAFS investigations on nanocomposites composed of surface-modified zirconium and zirconium/titanium mixed metal oxo-clusters and organic polymers

    International Nuclear Information System (INIS)

    Kickelbick, G.; Moraru, B.; Trimmel, G.; Schubert, U.; Feth, M.P.; Bertagnolli, H.

    2002-01-01

    The surface-modified oxometallate clusters Zr 6 (OH) 4 O 4 (OMc) 12 , Ti 4 Zr 4 O 6 (OBu) 4 (OMc) 16 , and Ti 2 Zr 4 O 4 (OBu) 2 (OMc) 14 (OMc methacrylate) as well as their nanocomposites with polystyrene, poly(methacrylic acid) and poly(methyl methacrylate) were investigated by EXAFS. Studies on the nanocomposites revealed that the structure of the cluster core is retained in the hybrid materials. (author)

  7. Surface modified natural zeolite as a carrier for sustained diclofenac release: A preliminary feasibility study.

    Science.gov (United States)

    de Gennaro, Bruno; Catalanotti, Lilia; Cappelletti, Piergiulio; Langella, Alessio; Mercurio, Mariano; Serri, Carla; Biondi, Marco; Mayol, Laura

    2015-06-01

    In view of zeolite potentiality as a carrier for sustained drug release, a clinoptilolite-rich rock from California (CLI_CA) was superficially modified with cetylpyridinium chloride and loaded with diclofenac sodium (DS). The obtained surface modified natural zeolites (SMNZ) were characterized by confocal scanning laser microscopy (CLSM), powder X-ray diffraction (XRPD) and laser light scattering (LS). Their flowability properties, drug adsorption and in vitro release kinetics in simulated intestinal fluid (SIF) were also investigated. CLI_CA is a Na- and K-rich clinoptilolite with a cationic exchange ability that fits well with its zeolite content (clinoptilolite=80 wt%); the external cationic exchange capacity is independent of the cationic surfactant used. LS and CLSM analyses have shown a wide distribution of volume diameters of SMNZ particles that, along with their irregular shape, make them cohesive with scarce flow properties. CLSM observation has revealed the localization of different molecules in/on SMNZ by virtue of their chemical nature. In particular, cationic and polar probes prevalently localize in SMNZ bulk, whereas anionic probes preferentially arrange themselves on SMNZ surface and the loading of a nonpolar molecule in/on SMNZ is discouraged. The adsorption rate of DS onto SMNZ was shown by different kinetic models highlighting the fact that DS adsorption is a pseudo-second order reaction and that the diffusion through the boundary layer is the rate-controlling step of the process. DS release in an ionic medium, such as SIF, can be sustained for about 5h through a mechanism prevalently governed by anionic exchange with a rapid final phase. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Environmentally responsive surface-modified silica nanoparticles for enhanced oil recovery

    International Nuclear Information System (INIS)

    Behzadi, Abed; Mohammadi, Aliasghar

    2016-01-01

    Environmentally responsive surface-modified nanoparticles are colloidal nanoparticles coated with, at least, two physicochemically distinct surface groups. Recent advances in the synthesis and production of nanoparticles have enabled the production of environmentally responsive surface-modified nanoparticles with both hydrophilic and hydrophobic surface groups. These nanoparticles act like colloidal surfactants. In this paper, environmentally responsive surface-modified silica nanoparticles are synthesized and used for enhancement of oil recovery. For this purpose, silica nanoparticles are coated with polyethylene glycol chains as hydrophilic agent and propyl chains as hydrophobic agent at various quantities, and their ability to modulate oil–water interface properties and oil recovery is examined. Oil–water interfacial tension and water surface tension are decreased by 50 % in the presence of silica nanoparticles coated with both agents. Measuring oil-drop contact angle on oil-wetted glass slides and carbonate rock sections, after aging in various surface-modified silica nanofluids, indicates that the wettability of various oil-wetted surfaces is modified from strongly oil-wet to water-wet. Flooding nanofluids to glass micro-models and pore-level investigations demonstrate that surface modification of silica nanoparticles, specially, with both hydrophilic and hydrophobic agents improves considerably their performance in increasing oil recovery and wettability alteration.

  9. Environmentally responsive surface-modified silica nanoparticles for enhanced oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Behzadi, Abed; Mohammadi, Aliasghar, E-mail: amohammadi@sharif.edu [Sharif University of Technology, Department of Chemical and Petroleum Engineering (Iran, Islamic Republic of)

    2016-09-15

    Environmentally responsive surface-modified nanoparticles are colloidal nanoparticles coated with, at least, two physicochemically distinct surface groups. Recent advances in the synthesis and production of nanoparticles have enabled the production of environmentally responsive surface-modified nanoparticles with both hydrophilic and hydrophobic surface groups. These nanoparticles act like colloidal surfactants. In this paper, environmentally responsive surface-modified silica nanoparticles are synthesized and used for enhancement of oil recovery. For this purpose, silica nanoparticles are coated with polyethylene glycol chains as hydrophilic agent and propyl chains as hydrophobic agent at various quantities, and their ability to modulate oil–water interface properties and oil recovery is examined. Oil–water interfacial tension and water surface tension are decreased by 50 % in the presence of silica nanoparticles coated with both agents. Measuring oil-drop contact angle on oil-wetted glass slides and carbonate rock sections, after aging in various surface-modified silica nanofluids, indicates that the wettability of various oil-wetted surfaces is modified from strongly oil-wet to water-wet. Flooding nanofluids to glass micro-models and pore-level investigations demonstrate that surface modification of silica nanoparticles, specially, with both hydrophilic and hydrophobic agents improves considerably their performance in increasing oil recovery and wettability alteration.

  10. Surface modified Al2O3 in fluorinated polyimide/Al2O3 ...

    Indian Academy of Sciences (India)

    the mechanical and thermal properties of polymers (Li et al. 2010). Herein, we wish to report the synthesis and characte- rization of fluorinated PI–Al2O3 nanocomposite films via in situ polymerization using different contents of surface modified Al2O3 nanoparticles as filler and fluorinated PI as the matrix. PI which was used ...

  11. Microgel-based surface modifying system for stimuli-responsive functional finishing of cotton

    NARCIS (Netherlands)

    Kulkarni, A.N.; Tourrette, A.; Warmoeskerken, Marinus; Jocic, D.

    2010-01-01

    An innovative strategy for functional finishing of textile materials is based on the incorporation of a thin layer of surface modifying systems (SMS) in the form of stimuli-sensitive microgels or hydrogels. Since the copolymerization of poly(N-isopropylacrylamide) with an ionizable polymer, such as

  12. Systematic screening of different surface modifiers for the production of physically stable nanosuspensions.

    Science.gov (United States)

    Lestari, Maria L A D; Müller, Rainer H; Möschwitzer, Jan P

    2015-03-01

    The role of a surface modifier is important in the formation of stable nanosuspensions. In this study, a simple and systematic screening method for selecting optimum surface modifiers was performed by utilizing a low-energy wet ball milling method. Nine surface modifiers from different classes with different stabilization mechanisms were applied on six different models of active pharmaceutical ingredients (API). Particle size analysis showed that at concentration five times higher than the critical micelle concentration, SDS and sodium cholate (anionic surfactant) showed the highest percent success to produce stable nanosuspensions with particle size smaller than 250 nm. Similar findings were also shown by poloxamer 188 (nonionic surfactant) and hydroxypropylmethylcellulose E5 (polymeric stabilizer) at concentration 1% (w/v) and 0.8% (w/v), respectively. In addition, combinations of anionic surfactant and nonionic surfactant as well as combinations of anionic surfactant and polymeric stabilizer showed high percent success in the formation of stable nanosuspensions. In general, no correlation can be found between the physicochemical characteristics of the model API (molecular weight, melting point, log P, pKa, and crystallinity) with its feasibility to be nanosized. The concentration and the principle of stabilization of surface modifier determine the formation of stable nanosuspensions. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  13. Environmentally responsive surface-modified silica nanoparticles for enhanced oil recovery

    Science.gov (United States)

    Behzadi, Abed; Mohammadi, Aliasghar

    2016-09-01

    Environmentally responsive surface-modified nanoparticles are colloidal nanoparticles coated with, at least, two physicochemically distinct surface groups. Recent advances in the synthesis and production of nanoparticles have enabled the production of environmentally responsive surface-modified nanoparticles with both hydrophilic and hydrophobic surface groups. These nanoparticles act like colloidal surfactants. In this paper, environmentally responsive surface-modified silica nanoparticles are synthesized and used for enhancement of oil recovery. For this purpose, silica nanoparticles are coated with polyethylene glycol chains as hydrophilic agent and propyl chains as hydrophobic agent at various quantities, and their ability to modulate oil-water interface properties and oil recovery is examined. Oil-water interfacial tension and water surface tension are decreased by 50 % in the presence of silica nanoparticles coated with both agents. Measuring oil-drop contact angle on oil-wetted glass slides and carbonate rock sections, after aging in various surface-modified silica nanofluids, indicates that the wettability of various oil-wetted surfaces is modified from strongly oil-wet to water-wet. Flooding nanofluids to glass micro-models and pore-level investigations demonstrate that surface modification of silica nanoparticles, specially, with both hydrophilic and hydrophobic agents improves considerably their performance in increasing oil recovery and wettability alteration.

  14. An investigation of the electrochemical action of the epoxy zinc-rich coatings containing surface modified aluminum nanoparticle

    Science.gov (United States)

    Jalili, M.; Rostami, M.; Ramezanzadeh, B.

    2015-02-01

    Aluminum nanoparticle was modified with amino trimethylene phosphonic acid (ATMP). The surface characterization of the nanoparticles was done by X-ray photo electron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) and thermal gravimetric analysis. The influence of the replacement of 2 wt% of zinc dust in the standard zinc-rich epoxy coating by nanoparticles on the electrochemical action of the coating was studied by electrochemical impedance spectroscopy (EIS) and salt spray tests. The morphology and phase composition of the zinc rich paints were evaluated by X-ray diffraction (XRD) and filed-emission scanning electron microscopy (FE-SEM). Results showed that the ATMP molecules successfully adsorbed on the surface of Al nanoparticles. Results obtained from salt spray and electrochemical measurements revealed that the addition of surface modified nanoparticles to the zinc rich coating enhanced its galvanic action and corrosion protection properties.

  15. Biosafety of Non-Surface Modified Carbon Nanocapsules as a Potential Alternative to Carbon Nanotubes for Drug Delivery Purposes

    Science.gov (United States)

    Tang, Alan C. L.; Hwang, Gan-Lin; Chang, Min-Yao; Tang, Zack C. W.; Tsai, Meng-Da; Luo, Chwan-Yao; Hoffman, Allan S.; Hsieh, Patrick C. H.

    2012-01-01

    Background Carbon nanotubes (CNTs) have found wide success in circuitry, photovoltaics, and other applications. In contrast, several hurdles exist in using CNTs towards applications in drug delivery. Raw, non-modified CNTs are widely known for their toxicity. As such, many have attempted to reduce CNT toxicity for intravenous drug delivery purposes by post-process surface modification. Alternatively, a novel sphere-like carbon nanocapsule (CNC) developed by the arc-discharge method holds similar electric and thermal conductivities, as well as high strength. This study investigated the systemic toxicity and biocompatibility of different non-surface modified carbon nanomaterials in mice, including multi-walled carbon nanotubes (MWCNTs), single-walled carbon nanotubes (SWCNTs), carbon nanocapsules (CNCs), and C60 fullerene (C60). The retention of the nanomaterials and systemic effects after intravenous injections were studied. Methodology and Principal Findings MWCNTs, SWCNTs, CNCs, and C60 were injected intravenously into FVB mice and then sacrificed for tissue section examination. Inflammatory cytokine levels were evaluated with ELISA. Mice receiving injection of MWCNTs or SWCNTs at 50 µg/g b.w. died while C60 injected group survived at a 50% rate. Surprisingly, mortality rate of mice injected with CNCs was only at 10%. Tissue sections revealed that most carbon nanomaterials retained in the lung. Furthermore, serum and lung-tissue cytokine levels did not reveal any inflammatory response compared to those in mice receiving normal saline injection. Conclusion Carbon nanocapsules are more biocompatible than other carbon nanomaterials and are more suitable for intravenous drug delivery. These results indicate potential biomedical use of non-surface modified carbon allotrope. Additionally, functionalization of the carbon nanocapsules could further enhance dispersion and biocompatibility for intravenous injection. PMID:22457723

  16. Strengthening and toughening of poly(L-lactide) composites by surface modified MgO whiskers

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Wei [Biomaterial Research Laboratory, Department of Material Science and Engineering, College of Science and Engineering, Jinan University, Guangzhou 510632 (China); Luo, Binghong, E-mail: tluobh@jnu.edu.cn [Biomaterial Research Laboratory, Department of Material Science and Engineering, College of Science and Engineering, Jinan University, Guangzhou 510632 (China); Engineering Research Center of Artificial Organs and Materials, Ministry of Education, Guangzhou 510632 (China); Qin, Xiaopeng; Li, Cairong [Biomaterial Research Laboratory, Department of Material Science and Engineering, College of Science and Engineering, Jinan University, Guangzhou 510632 (China); Liu, Mingxian; Ding, Shan [Biomaterial Research Laboratory, Department of Material Science and Engineering, College of Science and Engineering, Jinan University, Guangzhou 510632 (China); Engineering Research Center of Artificial Organs and Materials, Ministry of Education, Guangzhou 510632 (China); Zhou, Changren, E-mail: tcrz9@jnu.edu.cn [Biomaterial Research Laboratory, Department of Material Science and Engineering, College of Science and Engineering, Jinan University, Guangzhou 510632 (China); Engineering Research Center of Artificial Organs and Materials, Ministry of Education, Guangzhou 510632 (China)

    2015-03-30

    Highlights: • The grafted PLLA chain on the surface of g-MgO whisker was ruled out by FTIR spectroscopy and TG/DTG analyses. • The excellent dispersion of g-MgO whiskers and the strong interfacial adhesion of g-MgO whiskers/PLLA composite were proved by FSEM. • Comparing to MgO particles and MgO whiskers, fibrous-like g-MgO whiskers are the most effective reinforcing and toughening fillers for PLLA. - Abstract: To improve both the strength and toughness of poly(L-lactide) (PLLA), fibrous-like MgO whiskers with diameters of 0.15–1 μm and lengths of 15–110 μm were prepared, and subsequently surface modified with L-lactide to obtain grafted MgO whiskers (g-MgO whiskers). The structures and properties of MgO whiskers and g-MgO whiskers were studied. Then, a series of MgO whiskers/PLLA and g-MgO whiskers/PLLA composites were prepared by solution casting method, for comparison, MgO particles/PLLA composite was prepared too. The resulting composites were evaluated in terms of hydrophilicity, crystallinity, dispersion of whiskers, interfacial adhesion and mechanical performance by means of polarized optical microscopy (POM), contact angle measurement, field emission scanning electron microscope (FSEM), transmission electron microscopy (TEM) and tensile testing. The results revealed that the crystallization rate and hydrophilicity of PLLA were improved by the introduction of MgO whiskers and g-MgO whiskers. The g-MgO whiskers can disperse more uniformly in and show stronger interfacial adhesion with the matrix than MgO whiskers as a result of the surface modification. Due to the bridge effect of the whiskers and the excellent interfacial adhesion between g-MgO whiskers and PLLA, g-MgO whiskers/PLLA composites exhibited remarkably higher strength, modulus and toughness compared to the pristine PLLA, MgO particles/PLLA and MgO whiskers/PLLA composites.

  17. Gel Based Sunscreen Containing Surface Modified TiO2 Obtained by Sol-Gel Process: Proposal for a Transparent UV Inorganic Filter

    Directory of Open Access Journals (Sweden)

    Marina Paiva Abuçafy

    2016-01-01

    Full Text Available Inorganic UV filters, as titanium dioxide (TiO2, have become attractive because of their role in protecting the skin against the damage caused by the continuous exposure to the sun. However, their high refractive index, responsible for a white residue when applied on the skin, has led to the development of alternative inorganic materials, such as TiO2 nanoparticles. Thus, the aim of this study was the development of transparent and stable gel formulations containing surface modified TiO2 nanoparticles for application in sunscreens. Also, the physical and chemical properties of formulations containing TiO2 nanoparticles were evaluated. The UV absorption spectroscopy analyses indicated that the formulations containing TiO2 nanoparticles had a broad protection spectrum. The diffuse reflectance spectroscopy revealed that the use of PTSH surface modified TiO2 nanoparticles improved the transparency of the sunscreen formulations compared to that containing commercial ones. The rheology analyses showed that the amount of nanoparticles incorporated in the formulations influences the gel-like or liquid-like behavior. The results showed that the surface modified TiO2 nanoparticles are a promising innovative UV filter and the formulations containing these nanoparticles are interesting candidates for being used as sunscreen.

  18. Modeling of adsorption of toxic chromium on natural and surface modified lightweight expanded clay aggregate (LECA)

    Energy Technology Data Exchange (ETDEWEB)

    Kalhori, Ebrahim Mohammadi, E-mail: zarrabi62@yahoo.com [Department of Environmental Health Engineering, Faculty of Health, Alborz University of Medical Sciences, P.O. Box No: 31485/561, Alborz, Karaj (Iran, Islamic Republic of); Yetilmezsoy, Kaan, E-mail: yetilmez@yildiz.edu.tr [Department of Environmental Engineering, Faculty of Civil Engineering, Yildiz Technical University, 34220 Davutpasa, Esenler, Istanbul (Turkey); Uygur, Nihan, E-mail: uygur.n@gmail.com [Department of Environmental Engineering, Faculty of Engineering, Adiyaman University, 02040 Altinsehir, Adiyaman (Turkey); Zarrabi, Mansur, E-mail: mansor62@gmail.com [Department of Environmental Health Engineering, Faculty of Health, Alborz University of Medical Sciences, P.O. Box No: 31485/561, Alborz, Karaj (Iran, Islamic Republic of); Shmeis, Reham M. Abu, E-mail: r.abushmeis@yahoo.com [Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Isra University, PO Box 140753, code 11814, Amman (Jordan)

    2013-12-15

    Lightweight Expanded Clay Aggregate (LECA) modified with an aqueous solution of magnesium chloride MgCl{sub 2} and hydrogen peroxide H{sub 2}O{sub 2} was used to remove Cr(VI) from aqueous solutions. The adsorption properties of the used adsorbents were investigated through batch studies, Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), X-ray Fluorescence Spectroscopy (XRF), and Fourier Transform Infrared (FTIR) spectroscopy. The effect created by magnesium chloride on the modification of the LECA surface was greater than that of hydrogen peroxide solution and showed a substantial increase in the specific surface area which has a value of 76.12 m{sup 2}/g for magnesium chloride modified LECA while the values of 53.72 m{sup 2}/g, and 11.53 m{sup 2}/g were found for hydrogen peroxide modified LECA and natural LECA, respectively. The extent of surface modification with enhanced porosity in modified LECA was apparent from the recorded SEM patterns. XRD and FTIR studies of themodified LECA surface did not show any structural distortion. The adsorption kinetics was found to follow the modified Freundlich kinetic model and the equilibrium data fitted the Sips and Dubinin-Radushkevich equations better than other models. Maximum sorption capacities were found to be 198.39, 218.29 and 236.24 mg/g for natural LECA, surface modified LECA with H{sub 2}O{sub 2} and surface modified LECA with MgCl{sub 2}, respectively. Adsorbents were found to have only a weak effect on conductivity and turbidity of aqueous solutions. Spent natural and surface modified LECA with MgCl{sub 2} was best regenerated with HCl solution, while LECA surface modified with H{sub 2}O{sub 2} was best regenerated with HNO{sub 3} concentrated solution. Thermal method showed a lower regeneration percentage for all spent adsorbents.

  19. Development of the removal technology for toxic heavy metal ions by surface-modified activated carbon

    Energy Technology Data Exchange (ETDEWEB)

    Park, Geun Il; Song, Kee Chan; Kim, Kwang Wook; Kim, In Tae; Cho, Il Hoon; Kim, Joon Hyung

    2001-01-01

    Adsorption capacities of both radionuclides(uranium, cobalt) and toxic heavy metals (lead, cadmium and chromium) using double surface-modified activated carbon in wide pH ranges are extensively evaluated. Surface-modified activated carbons are classified as AC(as-received carbon), OAC(single surface-modified carbon with nitric acid solution) and OAC-Na(double surface-modified carbon with various alkali solutions). It is established that optimal condition for the second surface modification of OAC is to use the mixed solution of both NaOH and NaCl with total concentration of 0.1 N based on adsorption efficiencies of uranium and cobalt. Variations of adsorption efficiencies in pH ranges of 2{approx}10 and the adsorption capacities in batch adsorber and fixed bed for removal of both radionuclides and toxic heavy metals using OAC-Na were shown to be superior to that of the AC and OAC even in a low pH range. Capacity factors of OAC-Na for the removal of various metal ions are also excellent to that of AC or OAC. Quantitative analysis of capacity factors for each ions showed that adsorption capacity of OAC-Na increased by 30 times for uranium, 60 times for cobalt, 9 times for lead, 30 times for cadmium, 3 times for chromium compared to that of AC at pH 5, respectively. Adsorption capacity of OAC-Na is comparable to that of XAD-16-TAR used as commercial ion exchange resin.

  20. Surface Modified Characteristics of the Tetracalcium Phosphate as Light-Cured Composite Resin Fillers

    Directory of Open Access Journals (Sweden)

    Wen-Cheng Chen

    2014-01-01

    Full Text Available The objectives of this study are to characterize the properties of light-cured composite resins that are reinforced with whisker surface-modified particles of tetracalcium phosphate (TTCP and to investigate the influence of thermal cycling on the reinforced composites properties. The characteristics of ultimate diametral tensile strength (DTS, moduli, pH values, and fracture surfaces of the samples with different amounts of surface-modified TTCP (30%–60% were determined before and after thermal cycling between 5°C and 55°C in deionized water for 600 cycles. The trends of all groups were ductile prior to thermal cycling and the moduli of all groups increased after thermal cycling. The ductile property of the control group without filler was not significantly affected. Larger amounts of fillers caused the particles to aggregate, subsequently decreasing the resin’s ability to disperse external forces and leading to brittleness after thermal cycling. Therefore, the trend of composite resins with larger amounts of filler would become more brittle and exhibited higher moduli after thermal cycling. This developed composite resin with surface modified-TTCP fillers has the potential to be successful dental restorative materials.

  1. ACCOUNTING TREATMENTS SPECIFIC TO COUNTERPART COMMERCIAL TRANSACTIONS

    Directory of Open Access Journals (Sweden)

    Lucia PALIU - POPA

    2010-12-01

    Full Text Available Given the lack of availability of funds in foreign currency, felt in many countries, especially in the developing and developed countries and the economic or financial crisis in the global foreign exchange, counterpart commercial transactions were imposed as a “disarming” condition of the international trade. In the counterpart a purchase transaction is combined with a sale transaction, an import with an export in order to ensure balanced trade between the partners, trade that involves eliminating or reducing the currency as a payment source and its replacement with trade of goods and services. Thus, in the context of an acute need to export of greatly industrialized countries, where the overproduction phenomenon tends to have a chronic character, the counterpart has become a highly complex and sustainable phenomenon, which has seen a steady increase in the volume of amounts, with a geographical area and large variety of forms and mechanisms of implementation. Based on the characteristics and structure of counterpart transactions, we shall describe in this paper the accounting models specific to international trade, as part of the combined foreign trade transactions without neglecting the tax treatments that influence the entry in the accounts

  2. On the PEEK composites reinforced by surface-modified nano-silica

    International Nuclear Information System (INIS)

    Lai, Y.H.; Kuo, M.C.; Huang, J.C.; Chen, M.

    2007-01-01

    The nano-sized silica fillers reinforced poly(ether ether ketone) (PEEK) composites were fabricated by means of compression molding technique. The nano-sized silica, measuring 30 nm in size, was firstly modified by surface pretreatment with stearic acid. The performances and properties of the resulting PEEK/SiO 2 nanocomposites were examined in terms of tensile loading, hardness, dynamic mechanical analysis (DMA), thermomechanical analysis (TMA), thermogravimetry analysis (TGA), differential scanning calorimetry (DSC), X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The modified nano-silica was seen to disperse more uniformly than the unmodified counterpart. The XRD patterns of the modified silica reinforced PEEK composites reveal a systematic shift toward higher angles, suggesting the smaller d-spacing of the PEEK crystallites. The coefficient of thermal expansion (CTE) becomes lowered when the content of the nano-silica increases. Furthermore, the CTE of the modified silica filled PEEK nanocomposites shows the higher CTE values. A logic model is proposed. The increment of the dynamic modulus for the PEEK nanocomposites is up to 40% at elevated temperatures from 100 to 250 deg. C, indicating the apparent improvement of elevated temperature mechanical properties

  3. Electromagnetic Counterparts to Black Hole Mergers

    Science.gov (United States)

    Schnittman, Jeremy D.

    2011-01-01

    During the final moments of a binary black hole (BH) merger, the gravitational wave (GW) luminosity of the system is greater than the combined electromagnetic (EM) output of the entire observable universe. However, the extremely weak coupling between GWs and ordinary matter makes these waves very difficult to detect directly. Fortunately, the inspirating BH system will interact strongly-on a purely Newtonian level-with any surrounding material in the host galaxy, and this matter can in turn produce unique EM signals detectable at Earth. By identifying EM counterparts to GW sources, we will be able to study the host environments of the merging BHs, in turn greatly expanding the scientific yield of a mission like LISA. Here we present a comprehensive review of the recent literature on the subject of EM counterparts, as well as a discussion of the theoretical and observational advances required to fully realize the scientific potential of the field.

  4. Nicotine–magnesium aluminum silicate microparticle surface modified with chitosan for mucosal delivery

    Energy Technology Data Exchange (ETDEWEB)

    Kanjanakawinkul, Watchara [Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002 (Thailand); Rades, Thomas [School of Pharmacy, University of Otago, Dunedin 9054 (New Zealand); Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen (Denmark); Puttipipatkhachorn, Satit [Department of Manufacturing Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400 (Thailand); Pongjanyakul, Thaned, E-mail: thaned@kku.ac.th [Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002 (Thailand)

    2013-04-01

    Magnesium aluminum silicate (MAS), a negatively charged clay, and nicotine (NCT), a basic drug, can interact electrostatically to form microparticles. Chitosan (CS) was used for the surface modification of the microparticles, and a lyophilization method was used to preserve the original particle morphology. The microparticles were characterized in terms of their physicochemical properties, NCT content, mucoadhesive properties, and release and permeation across porcine esophageal mucosa. The results showed that the microparticles formed via electrostatic interaction between MAS and protonated NCT had an irregular shape and that their NCT content increased with increasing NCT ratios in the microparticle preparation solution. High molecular weight CS (800 kDa) adsorbed to the microparticle surface and induced a positive surface charge. CS molecules intercalated into the MAS silicate layers and decreased the crystallinity of the microparticles, leading to an increase in the release rate and diffusion coefficient of NCT from the microparticles. Moreover, the microparticle surface modified with CS was found to have higher NCT permeation fluxes and mucoadhesive properties, which indicated the significant role of CS for NCT mucosal delivery. However, the enhancement of NCT permeation and of mucoadhesive properties depended on the molecular weight and concentration of CS. These findings suggest that NCT-MAS microparticle surface modified with CS represents a promising mucosal delivery system for NCT. Highlights: ► Nicotine–magnesium aluminum silicate microparticles were prepared using electrostatic interaction. ► Lyophilization was used for drying and maintaining an original morphology of the microparticles. ► Chitosan (CS) was used for surface modification of the microparticles at acidic pH. ► Surface modification using CS caused an increase in release and permeation of nicotine. ► Microparticle surface-modified with CS presented better mucoadhesive properties.

  5. Aflatoxin Toxicity Reduction in Feed by Enhanced Binding to Surface-Modified Clay Additives

    Science.gov (United States)

    Jaynes, William F.; Zartman, Richard E.

    2011-01-01

    Animal feeding studies have demonstrated that clay additives, such as bentonites, can bind aflatoxins in ingested feed and reduce or eliminate the toxicity. Bentonite deposits are found throughout the world and mostly consist of expandable smectite minerals, such as montmorillonite. The surfaces of smectite minerals can be treated with organic compounds to create surface-modified clays that more readily bind some contaminants than the untreated clay. Montmorillonites treated with organic cations, such as hexadecyltrimethylammonium (HDTMA) and phenyltrimethylammonium (PTMA), more effectively remove organic contaminants, such as benzene and toluene, from water than untreated clay. Similarly, montmorillonite treated with PTMA (Kd = 24,100) retained more aflatoxin B1 (AfB1) from aqueous corn flour than untreated montmorillonite (Kd = 944). Feed additives that reduced aflatoxin toxicity in animal feeding studies adsorbed more AfB1 from aqueous corn flour than feed additives that were less effective. The organic cations HDTMA and PTMA are considered toxic and would not be suitable for clay additives used in feed or food, but other non-toxic or nutrient compounds can be used to prepare surface-modified clays. Montmorillonite (SWy) treated with choline (Kd = 13,800) and carnitine (Kd = 3960) adsorbed much more AfB1 from aqueous corn flour than the untreated clay (Kd = 944). A choline-treated clay prepared from a reduced-charge, high-charge montmorillonite (Kd = 20,100) adsorbed more AfB1 than the choline-treated high-charge montmorillonite (Kd = 1340) or the untreated montmorillonite (Kd = 293). Surface-modified clay additives prepared using low-charge smectites and nutrient or non-toxic organic compounds might be used to more effectively bind aflatoxins in contaminated feed or food and prevent toxicity. PMID:22069725

  6. EXAFS investigations on nanocomposites composed of surface-modified zirconium and zirconium/titanium mixed metal oxo-clusters and organic polymers

    CERN Document Server

    Kickelbick, G; Trimmel, G; Schubert, U; Feth, M P; Bertagnolli, H

    2002-01-01

    The surface-modified oxometallate clusters Zr sub 6 (OH) sub 4 O sub 4 (OMc) sub 1 sub 2 , Ti sub 4 Zr sub 4 O sub 6 (OBu) sub 4 (OMc) sub 1 sub 6 , and Ti sub 2 Zr sub 4 O sub 4 (OBu) sub 2 (OMc) sub 1 sub 4 (OMc methacrylate) as well as their nanocomposites with polystyrene, poly(methacrylic acid) and poly(methyl methacrylate) were investigated by EXAFS. Studies on the nanocomposites revealed that the structure of the cluster core is retained in the hybrid materials. (author)

  7. Electromagnetic counterparts to structured jets from gravitational wave detected mergers

    Science.gov (United States)

    Lamb, Gavin P.; Kobayashi, Shiho

    2017-12-01

    We show the peak magnitude for orphan afterglows from the jets of gravitational wave (GW) detected black hole/neutron star - neutron star (BH/NS-NS) mergers highly depend on the jet half-opening angle θj. Short γ-ray bursts (GRBs) with a homogeneous jet structure and θj > 10°, the orphan afterglow viewed at the typical inclination for a GW detected event, 38°, are brighter at optical frequencies than the comparable macronova emission. Structured jets, where the energetics and Lorentz factor Γ vary with angle from the central axis, may have low-Γ components where the prompt emission is suppressed; GW electromagnetic (EM) counterparts may reveal a population of failed-GRB orphan afterglows. Using a Monte Carlo method assuming an NS-NS detection limit we show the fraction of GW-EM counterparts from homogeneous, two-component, power-law structured and Gaussian jets where the variable structure models include a wide low energy and Γ component: for homogeneous jets, with a θj = 6° and typical short GRB parameters, we find r-band magnitude mr ≤ 21 counterparts for ∼13.6 per cent of GW detected mergers; where jet structure extends to a half-opening angle of 25°, two-component jets produce mr ≤ 21 counterparts in ∼30 per cent of GW detected mergers, power-law structured-jets result in ∼37 per cent and Gaussian jets with our parameters ∼13 per cent. We show the features in the light curves from orphan afterglows can be used to indicate the presence of extended structure.

  8. Acrylic acid surface-modified contact lens for the culture of limbal stem cells.

    Science.gov (United States)

    Zhang, Hong; Brown, Karl David; Lowe, Sue Peng; Liu, Guei-Sheung; Steele, David; Abberton, Keren; Daniell, Mark

    2014-06-01

    Surface treatment to a biomaterial surface has been shown to modify and help cell growth. Our aim was to determine the best surface-modified system for the treatment of limbal stem cell deficiency (LSCD), which would facilitate expansion of autologous limbal epithelial cells, while maintaining cultivated epithelial cells in a less differentiated state. Commercially available contact lenses (CLs) were variously surface modified by plasma polymerization with ratios of acrylic acid to octadiene tested at 100% acrylic acid, 50:50% acrylic acid:octadiene, and 100% octadiene to produce high-, mid-, and no-acid. X-ray photoelectron spectroscopy was used to analyze the chemical composition of the plasma polymer deposited layer. Limbal explants cultured on high acid-modified CLs outgrew more cells. Immunofluorescence and RT2-PCR array results indicated that a higher acrylic acid content can also help maintain progenitor cells during ex vivo expansion of epithelial cells. This study provides the first evidence for the ability of high acid-modified CLs to preserve the stemness and to be used as substrates for the culture of limbal cells in the treatment of LSCD.

  9. Formulation design and in vitro physicochemical characterization of surface modified self-nanoemulsifying formulations (SNEFs) of gentamicin.

    Science.gov (United States)

    Umeyor, Chukwuebuka; Attama, Anthony; Uronnachi, Emmanuel; Kenechukwu, Franklin; Nwakile, Calistus; Nzekwe, Ifeanyi; Okoye, Eric; Esimone, Charles

    2016-01-30

    Self-nanoemulsifying formulations (SNEFs) structured with PEG 4000 as PEGylated SNEFs, were formulated after solubility studies using rational blends of soybean oil, a combination of Kolliphor(®) EL and Kolliphor(®) P188 as surfactants, and Transcutol(®) HP as co-surfactant, and evaluated for oral delivery of gentamicin. Incorporation of gentamicin and PEG 4000 reduced the initial area of nanoemulsion of the ternary phase diagrams produced by water titration method using oil, surfactant mixture and co-surfactant. Emulsion droplets were in the nanometer scale ranging from 80-210 nm. FT-IR study revealed that gentamicin structure remained intact in all formulations, and SEM micrographs showed spherical globules. Zeta potentials of SNEFs were in the range of -25.4 to -42.5 mV, and showed a stable system with minor flips in electrostatic charges. There was high in vitro diffusion-dependent permeation of gentamicin from the SNEFs. Results obtained in this work showed that oral delivery of gentamicin was improved by formulation as surface modified SNEFs. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Control of Surface Modified Layer on Metallic Biomaterials by AN Advanced Elid Grinding System Eg-X

    Science.gov (United States)

    Mizutani, Masayoshi; Komotori, Jun; Katahira, Kazutoshi; Ohmori, Hitoshi

    The biocompatibility of titanium implants with different surface properties is investigated. We prepared three types of specimens, one ground by the newly developed ELID grinding system, another ground by conventional ELID grinding, and the other polished by SiO2 powder. These surfaces were characterized and, the number of cell and cytotoxicity in in-vitro were measured. Energy Dispersive X-ray Spectroscopy (EDS), X-ray Photoelectron Spectroscopy (XPS) and Transmission Electron Microscope (TEM) revealed that the modified ELID system can create a significantly thick oxide layer and a diffused oxide layer, and also can control the thickness of a modified layer. The results of cell number and cytotoxicity showed that the sample ground by the modified system had the highest biocompatibility. This may have been caused by improvement of chemical properties due to a surface modified layer. The above results suggest that this newly developed ELID grinding system can create the desirable surface properties. Consequently, this system appears to offer significant future promise for use in biomaterials and other engineering components.

  11. Acute and subchronic toxicity analysis of surface modified paclitaxel attached hydroxyapatite and titanium dioxide nanoparticles.

    Science.gov (United States)

    Venkatasubbu, Gopinath Devanand; Ramasamy, S; Gaddam, Pramod Reddy; Kumar, J

    2015-01-01

    Nanoparticles are widely used for targeted drug delivery applications. Surface modification with appropriate polymer and ligands is carried out to target the drug to the affected area. Toxicity analysis is carried out to evaluate the safety of the surface modified nanoparticles. In this study, paclitaxel attached, folic acid functionalized, polyethylene glycol modified hydroxyapatite and titanium dioxide nanoparticles were used for targeted drug delivery system. The toxicological behavior of the system was studied in vivo in rats and mice. Acute and subchronic studies were carried out. Biochemical, hematological, and histopathological analysis was also done. There were no significant alterations in the biochemical parameters at a low dosage. There was a small change in alkaline phosphatase (ALP) level at a high dosage. The results indicate a safe toxicological profile.

  12. Combined slurry and cavitation erosion resistance of surface modified SS410 stainless steel

    Science.gov (United States)

    Amarendra, H. J.; Pratap, M. S.; Karthik, S.; Punitha Kumara, M. S.; Rajath, H. C.; Ranjith, H.; Shubhatunga, S. V.

    2018-03-01

    Slurry erosion and combined slurry and cavitation erosion resistance of thermal spray coatings are studied and compared with the as-received martensitic stainless steel material. 70Ni-Cr coatings are deposited on SS 410 material through plasma thermal spray process. The synergy effect of the combined slurry and cavitation erosion resistance of plasma thermal spray coatings were investigated in a slurry pot tester in the presence of bluff bodies known as Cavitation Inducers. Results showed the combined slurry and cavitation erosion resistance of martensitic stainless steel - 410 can be improved by plasma thermal spray coating. It is observed that the plasma spray coated specimens are better erosion resistant than the as- received material, subjected to erosion test under similar conditions. As-received and the surface modified steels are mechanically characterized for its hardness, bending. Morphological studies are conducted through scanning electron microscope.

  13. Iron carbide on titania surface modified with group VA oxides as Fischer-Tropsch catalysts

    International Nuclear Information System (INIS)

    Wachs, I.E.; Fiato, R.A.; Chersich, C.C.

    1986-01-01

    A catalyst is described comprising iron carbide supported on a surface modified titania wherein the support comprises an oxide of a metal selected form the group consisting of niobium, vanadium, tantalum or mixture thereof supported on the titania wherein at least a portion of the supported oxide of niobium, vanandium, tantalum or mixture is in a non-crystalline form. The amount of the supported oxide ranges from about 0.5 to 25 weight percent metal oxide on the titania support based on the total support composition and the catalyst contains at least about 2 milligrams of iron, calculated as Fe/sub 2/O/sub 3/, per square meter of support surface

  14. Corrosive characteristics of surface-modified stainless steel bipolar plate in solid polymer fuel cell

    Science.gov (United States)

    Zhang, Xiaowen; Wang, Lixia; Sun, Juncai

    2015-03-01

    In this paper, corrosion behavior of an AISI 304 stainless steel modified by niobium or niobium nitride (denoted as niobized 304 SS and Nb-N 304 SS, respectively) is investigated in simulated solid polymer fuel cell (SPFC) operating conditions. Potentiodynamic polarizations show that the corrosion potentials of surface modified 304 SS shift to positive direction while the corrosion current densities decrease greatly comparing with the bare 304 SS in simulated anodic SPFC environments. The order of corrosive resistance in corrosive potential, corrosive current density and pitting potential is: Nb-N 304 SS > niobized 304 SS > bare 304 SS. In the methanol-fueled SPFC operating conditions, the results show that the corrosion resistance of bare and niobized 304 SS increases with the methanol concentration increasing in the test solutions.

  15. Corrosion resistance of the AISI 304, 316 and 321 stainless steel surfaces modified by laser

    Science.gov (United States)

    Szubzda, B.; Antończak, A.; Kozioł, P.; Łazarek, Ł.; Stępak, B.; Łęcka, K.; Szmaja, A.; Ozimek, M.

    2016-02-01

    The article presents the analysis results of the influence of laser fluence on physical and chemical structure and corrosion resistance of stainless steel surfaces modified by irradiating with nanosecond-pulsed laser. The study was carried out for AISI 304, AISI 316 and AISI 321 substrates using Yb:glass fiber laser. All measurements were made for samples irradiated in a broad range of accumulated fluence (10÷400 J/cm2). The electrochemical composition (by EDX) and surface morphology (by SEM) of the prepared surfaces were carried out. Finally, corrosion resistance was analyzed by a potentiodynamic electrochemical test. The obtained results showed very high corrosion resistance for samples made by fluency of values lower than 100 J/cm2. In this case, higher values of corrosion potentials and breakdown potentials were observed. A correlation between corrosion phenomena, the range of laser power (fluence) and the results of chemical and structural tests were also found.

  16. Acute and subchronic toxicity analysis of surface modified paclitaxel attached hydroxyapatite and titanium dioxide nanoparticles

    Science.gov (United States)

    Venkatasubbu, Gopinath Devanand; Ramasamy, S; Gaddam, Pramod Reddy; Kumar, J

    2015-01-01

    Nanoparticles are widely used for targeted drug delivery applications. Surface modification with appropriate polymer and ligands is carried out to target the drug to the affected area. Toxicity analysis is carried out to evaluate the safety of the surface modified nanoparticles. In this study, paclitaxel attached, folic acid functionalized, polyethylene glycol modified hydroxyapatite and titanium dioxide nanoparticles were used for targeted drug delivery system. The toxicological behavior of the system was studied in vivo in rats and mice. Acute and subchronic studies were carried out. Biochemical, hematological, and histopathological analysis was also done. There were no significant alterations in the biochemical parameters at a low dosage. There was a small change in alkaline phosphatase (ALP) level at a high dosage. The results indicate a safe toxicological profile. PMID:26491315

  17. Evaluation of Antibacterial Activity of Titanium Surface Modified by PVD/PACVD Process.

    Science.gov (United States)

    Ji, Min-Kyung; Lee, Min-Joo; Park, Sang-Won; Lee, Kwangmin; Yun, Kwi-Dug; Kim, Hyun-Seung; Oh, Gye-Jeong; Kim, Ji-Hyun; Lim, Hyun-Pil

    2016-02-01

    The aim of this study was to evaluate the response of Streptococcus mutans (S. mutans) via crystal violet staining assay on titanium surface modified by physical vapor deposition/plasma assisted chemical vapor deposition process. Specimens were divided into the following three groups: polished titanium (control group), titanium modified by DC magnetron sputtering (group TiN-Ti), and titanium modified by plasma nitriding (group N-Ti). Surface characteristics of specimens were observed by using nanosurface 3D optical profiler and field emission scanning electron microscope. Group TiN-Ti showed TiN layer of 1.2 microm in thickness. Group N-Ti was identified as plasma nitriding with X-ray photoelectron spectroscopy. Roughness average (Ra) of all specimens had values 0.05). Within the process condition of this study, modified titanium surfaces by DC magnetron sputtering and plasma nitriding did not influence the adhesion of S. mutans.

  18. Surface-modified yeast cells: A novel eukaryotic carrier for oral application.

    Science.gov (United States)

    Kenngott, Elisabeth E; Kiefer, Ruth; Schneider-Daum, Nicole; Hamann, Alf; Schneider, Marc; Schmitt, Manfred J; Breinig, Frank

    2016-02-28

    The effective targeting and subsequent binding of particulate carriers to M cells in Peyer's patches of the gut is a prerequisite for the development of oral delivery systems. We have established a novel carrier system based on cell surface expression of the β1-integrin binding domain of invasins derived from Yersinia enterocolitica and Yersinia pseudotuberculosis on the yeast Saccharomyces cerevisiae. All invasin derivatives were shown to be effectively expressed on the cell surface and recombinant yeast cells showed improved binding to both human HEp-2 cells and M-like cells in vitro. Among the different derivatives tested, the integrin-binding domain of Y. enterocolitica invasin proved to be the most effective and was able to target Peyer's patches in vivo. In conclusion, cell surface-modified yeasts might provide a novel bioadhesive, eukaryotic carrier system for efficient and targeted delivery of either antigens or drugs via the oral route. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Titania nanotube arrays surface-modified with ZnO for enhanced photocatalytic applications

    Energy Technology Data Exchange (ETDEWEB)

    Nageri, Manoj; Kalarivalappil, Vijila; Vijayan, Baiju K.; Kumar, Viswanathan, E-mail: vkumar10@yahoo.co.in

    2016-05-15

    Highlights: • Heterostructures of TNA/ZnO synthesised through potentiostatic anodisation followed by hydrothermal method. • Evaluation of morphological features of the heterostructure with hydrothermal processing time. • Correlation of photocatalytic activity of the hetrostructure with its morphology and surface texture. - Abstract: Well ordered titanium dioxide nanotube arrays (TNA) of average diameter 129 nm and wall thickness of 25 nm were fabricated through potentiostatic anodisation of titanium (Ti) metal substrates. Such TNA were subsequently surface-modified with various amounts of zinc oxide (ZnO) nanopowders using hydrothermal technique to obtain heterogeneous TNA/ZnO nanostructures. The crystalline phase and surface microstructure of the heterostructures were determined by X-ray diffraction, Raman spectroscopy and scanning electron microscopy respectively. The morphology of the heterostructures strongly depended on the hydrothermal conditions employed. The photocatalytic activity of the heterostructures have also been investigated and correlated with their surface morphology and texture.

  20. Kilonova Counterparts of Binary Neutron Star Mergers

    Science.gov (United States)

    Metzger, Brian

    2018-01-01

    The merger of a binary neutron star is accompanied by the ejection of neutron-rich matter into space at velocities up to several tenths that of light, which synthesizes rare heavy isotopes through the rapid neutron capture process (r-process). The radioactive decay of these nuclei was predicted by Metzger et al. (2010) to power an optical transient roughly 1000 times more luminous than a classical nova (a "kilonova"), which is among the most promising electromagnetic counterparts to accompany gravitational wave signal from the merger. I will describe how the luminosities, color, and spectra of the kilonova emission inform the properties of the merging binary (neutron star masses/radii and inclination angle) and the long sought origin of the heaviest elements in the Universe. Results will be discussed in the context of recent discoveries by Advanced LIGO/Virgo.

  1. Structure–Property Relationships of Inorganically Surface-Modified Zeolite Molecular Sieves for Nanocomposite Membrane Fabrication

    KAUST Repository

    Lydon, Megan E.

    2012-05-03

    A multiscale experimental study of the structural, compositional, and morphological characteristics of aluminosilicate (LTA) and pure-silica (MFI) zeolite materials surface-modified with MgO xH y nanostructures is presented. These characteristics are correlated with the suitability of such materials in the fabrication of LTA/Matrimid mixed-matrix membranes (MMMs) for CO 2/CH 4 separations. The four functionalization methods studied in this work produce surface nanostructures that may appear superficially similar under SEM observation but in fact differ considerably in shape, size, surface coverage, surface area/roughness, degree of attachment to the zeolite surface, and degree of zeolite pore blocking. The evaluation of these characteristics by a combination of TEM, HRTEM, N 2 physisorption, multiscale compositional analysis (XPS, EDX, and ICP-AES elemental analysis), and diffraction (ED and XRD) allows improved understanding of the origin of disparate gas permeation properties observed in MMMs made with four types of surface-modified zeolite LTA materials, as well as a rational selection of the method expected to result in the best enhancement of the desired properties (in the present case, CO 2/CH 4 selectivity increase without sacrificing permeability). A method based on ion exchange of the LTA with Mg 2+, followed by base-induced precipitation and growth of MgO xH y nanostructures, deemed "ion exchange functionalization" here, offers modified particles with the best overall characteristics resulting in the most effective MMMs. LTA/Matrimid MMMs containing ion exchange functionalized particles had a considerably higher CO 2/CH 4 selectivity (∼40) than could be obtained with the other functionalization techniques (∼30), while maintaining a CO 2 permeability of ∼10 barrers. A parallel study on pure silica MFI surface nanostructures is also presented to compare and contrast with the zeolite LTA case. © 2012 American Chemical Society.

  2. Preparation and Evaluation of Surface Modified Lactose Particles for Improved Performance of Fluticasone Propionate Dry Powder Inhaler.

    Science.gov (United States)

    Singh, Deepak J; Jain, Rajesh R; Soni, P S; Abdul, Samad; Darshana, Hegde; Gaikwad, Rajiv V; Menon, Mala D

    2015-08-01

    Dry powder inhalers (DPI) are generally formulated by mixing micronized drug particles with coarse lactose carrier particles to assist powder handling during the manufacturing and powder aerosol delivery during patient use. In the present study, surface modified lactose (SML) particles were produced using force control agents, and their in vitro performance on dry powder inhaler (DPI) formulation of Fluticasone propionate was studied. With a view to reduce surface passivation of high surface free energy sites on the most commonly used DPI carrier, α- lactose monohydrate, effects of various force control agents such as Pluronic F-68, Cremophor RH 40, glyceryl monostearate, polyethylene glycol 6000, magnesium stearate, and soya lecithin were studied. DPI formulations prepared with SML showed improved flow properties, and atomic force microscopy (AFM) studies revealed decrease in surface roughness. The DSC and X-ray diffraction patterns of SML showed no change in the crystal structure and thermal behavior under the experimental conditions. The fine particle fraction (FPF) values of lactose modified with Pluronic F-68, Cremophor RH 40, glyceryl monostearate were improved, with increase in concentration up to 0.5%. Soya lecithin and PEG 6000 modified lactose showed decrease in FPF value with increase in concentration. Increase in FPF value was observed with increasing concentration of magnesium stearate. Two different DPI devices, Rotahaler(®) and Diskhaler(®), were compared to evaluate the performance of SML formulations. FPF value of all SML formulations were higher using both devices as compared to the same formulations prepared using untreated lactose. One month stability of SML formulations at 40°C/75% RH, in permeable polystyrene tubes did not reveal any significant changes in FPF values. SML particles can help in reducing product development hindrances and improve inhalational properties of DPI.

  3. A vapor response mechanism study of surface-modified single-walled carbon nanotubes coated chemiresistors and quartz crystal microbalance sensor arrays.

    Science.gov (United States)

    Lu, Hung-Ling; Lu, Chia-Jung; Tian, Wei-Cheng; Sheen, Horn-Jiunn

    2015-01-01

    This paper compares the selectivity and discusses the response mechanisms of various surface-modified, single-walled carbon nanotube (SWCNT)-coated sensor arrays for the detection of volatile organic compounds (VOCs). Two types of sensor platforms, chemiresistor and quartz crystal microbalance (QCM), were used to probe the resistance changes and absorption masses during vapor sensing. Four sensing materials were used in this comparison study: pristine, acidified, esterified, and surfactant (sodium dodecyl sulfate, SDS)-coated SWCNTs. SWCNT-coated QCMs reached the response equilibrium faster than the chemiresistors did, which revealed a delay diffusion behavior at the inter-tube junction. In addition, the calibration lines for QCMs were all linear, but the chemiresistors showed curvature calibration lines which indicated less effectiveness of swelling at high concentrations. While the sorption of vapor molecules caused an increase in the resistance for most SWCNTs due to the swelling, the acidified SWCNTs showed no responses to nonpolar vapors and a negative response to hydrogen bond acceptors. This discovery provided insight into the inter-tube interlocks and conductivity modulation of acidified SWCNTs via a hydrogen bond. The results in this study provide a stepping-stone for further understanding of the mechanisms behind the vapor selectivity of surface-modified SWCNT sensor arrays. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Electrochemical hydrogen storage of Ti-V-based body-centered-cubic phase alloy surface-modified with AB5 nanoparticles

    International Nuclear Information System (INIS)

    Yu, X.B.; Walker, G.S.; Grant, D.M.; Wu, Z.; Xia, B.J.; Shen, J.

    2005-01-01

    A composite of Ti-V-based bcc phase alloy surface-modified with AB 5 nanoparticles was prepared by ball milling. The composite showed significantly improved electrochemical hydrogen release capacities. For example, the 30 min ball milled Ti-30V-15Mn-15Cr+10 wt %AB 5 showed a discharge capacity in the first cycle, at 353 K, of 886 mA h g -1 , corresponding to 3.38 wt % of hydrogen, with a 45 mA g -1 discharge current. It is thought that this high capacity is due to the enhanced electrochemical-catalytic activity from the alloy surface covered with AB 5 nanoparticles, which not only have better charge-discharge capacity themselves, acting as both an electrocatalyst and a microcurrent collector, but also result in the greatly enhanced hydrogen atomic diffusivities in the nanocrystalline relative to their conventional coarse-grained counterparts. These results provide new insight for use of Ti-V-based bcc phase alloy for high-energy batteries

  5. UMCP MIST counter-part test

    International Nuclear Information System (INIS)

    di Marzo, M.; Almenas, K.; Hsu, Y.Y.; Pertmer, G.A.

    1990-01-01

    Two small break loss-of-coolant accident (LOCA) transients are compared to illustrate a scaling methodology for reduced pressure integral facilities. Mapping test 3004 is conducted in the Multiloop Integral System Test (MIST) full pressure, full height facility. The counter-part test MISO3l7 is scaled and performed in the reduced height, reduced pressure UMCP facility. Inventory is used as the chronological scale and pressure, normalized with the initial and system saturation pressures, is used as characteristic parameter to describe the system behavior. The appropriately normalized results conclusively demonstrate that: (a) the same phenomena are observed in the two facilities; (b) the sequence of events is analogous and (c) the trends described by the normalized pressure versus inventory traces are in good quantitative agreement. Each energy transport mode traversed by the two facilities is compared and the phenomena present are described in detail. The differences between the high and reduced pressure tests are outlined. The findings clearly indicate that pressure and height can be scaled for transient where limited boundary conditions are applied and where the break is subcooled. A statement on sensitivity to the initial conditions is also included to define the limitations of the quantitative results

  6. Surface-modified silica colloidal crystals: nanoporous films and membranes with controlled ionic and molecular transport.

    Science.gov (United States)

    Zharov, Ilya; Khabibullin, Amir

    2014-02-18

    Nanoporous membranes are important for the study of the transport of small molecules and macromolecules through confined spaces and in applications ranging from separation of biomacromolecules and pharmaceuticals to sensing and controlled release of drugs. For many of these applications, chemists need to gate the ionic and molecular flux through the nanopores, which in turn depends on the ability to control the nanopore geometry and surface chemistry. Most commonly used nanoporous membrane materials are based on polymers. However, the nanostructure of polymeric membranes is not well-defined, and their surface is hard to modify. Inorganic nanoporous materials are attractive alternatives for polymers in the preparation of nanoporous membranes. In this Account, we describe the preparation and surface modification of inorganic nanoporous films and membranes self-assembled from silica colloidal spheres. These spheres form colloidal crystals with close-packed face centered cubic lattices upon vertical deposition from colloidal solutions. Silica colloidal crystals contain ordered arrays of interconnected three dimensional voids, which function as nanopores. We can prepare silica colloidal crystals as supported thin films on various flat solid surfaces or obtain free-standing silica colloidal membranes by sintering the colloidal crystals above 1000 °C. Unmodified silica colloidal membranes are capable of size-selective separation of macromolecules, and we can surface-modify them in a well-defined and controlled manner with small molecules and polymers. For the surface modification with small molecules, we use silanol chemistry. We grow polymer brushes with narrow molecular weight distribution and controlled length on the colloidal nanopore surface using atom transfer radical polymerization or ring-opening polymerization. We can control the flux in the resulting surface-modified nanoporous films and membranes by pH and ionic strength, temperature, light, and small molecule

  7. Surface-modified polymeric pads for enhanced performance during chemical mechanical planarization

    International Nuclear Information System (INIS)

    Deshpande, S.; Dakshinamurthy, S.; Kuiry, S.C.; Vaidyanathan, R.; Obeng, Y.S.; Seal, S.

    2005-01-01

    The chemical mechanical planarization (CMP) process occurs at an atomic level at the slurry/wafer interface and hence slurries and polishing pads play a critical role in their successful implementation. Polyurethane is a commonly used polymer in the manufacturing of CMP pads. These pads are incompatible with some chemicals present in the CMP slurries, such as hydrogen peroxide. To overcome these problems, Psiloquest has developed new Application Specific Pads (ASP). Surface of such pads has been modified by depositing a thin film of tetraethyl orthosilicate using plasma-enhanced chemical vapor deposition (PECVD) process. In the present study, mechanical properties of such coated pads have been investigated using nanoindentation. The surface morphology and the chemistry of the ASP were studied using scanning electron microcopy, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy techniques. It was observed that mechanical and chemical properties of the pad top surface are a function of the PECVD coating time. Such PECVD-treated pads are found to be hydrophilic and do not require storage in aqueous media during the not-in-use period. The metal removal rate using such surface-modified polishing pads was found to increase linearly with the PECVD coating time

  8. Surface modified zeolite-based granulates for the sustained release of diclofenac sodium.

    Science.gov (United States)

    Serri, Carla; de Gennaro, Bruno; Quagliariello, Vincenzo; Iaffaioli, Rosario Vincenzo; De Rosa, Giuseppe; Catalanotti, Lilia; Biondi, Marco; Mayol, Laura

    2017-03-01

    In this study, a granulate for the oral controlled delivery of diclofenac sodium (DS), an anionic sparingly soluble nonsteroidal anti-inflammatory drug, has been realized by wet granulation, using a surface modified natural zeolite (SMNZ) as an excipient. The surface modification of the zeolite has been achieved by means of a cationic surfactant, so as to allow the loading of DS through ionic interaction and bestow a control over the drug release mechanism. The granules possessed a satisfactory dosage uniformity, a flowability suitable for an oral dosage form manufacturing, along with a sustained drug release up to 9h, driven by both ion exchange and transport kinetics. Furthermore, the obtained granulate did not elicit a significant cytotoxicity and could also induce a prolonged anti-inflammatory effect on RAW264.7 cells. Taking also into account that natural zeolites are generally abundant and economic, SMNZ can be considered as an attracting alternative excipient for the production of granules with sustained release features. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Surface-modified sulfur nanoparticles: an effective antifungal agent against Aspergillus niger and Fusarium oxysporum.

    Science.gov (United States)

    Choudhury, Samrat Roy; Ghosh, Mahua; Mandal, Amrita; Chakravorty, Dipankar; Pal, Moumita; Pradhan, Saheli; Goswami, Arunava

    2011-04-01

    Surface-modified sulfur nanoparticles (SNPs) of two different sizes were prepared via a modified liquid-phase precipitation method, using sodium polysulfide and ammonium polysulfide as starting material and polyethylene glycol-400 (PEG-400) as the surface stabilizing agent. Surface topology, size distribution, surface modification of SNPs with PEG-400, quantitative analysis for the presence of sulfur in nanoformulations, and thermal stability of SNPs were determined by atomic force microscopy (AFM), dynamic light scattering (DLS) plus high-resolution transmission electron microscopy (HR-TEM), fourier transform infrared (FT-IR) spectroscopy, energy dispersive X-ray (EDX) spectroscopy, and thermogravimetric analysis (TGA), respectively. A simultaneous study with micron-sized sulfur (S(0)) and SNPs was carried out to evaluate their fungicidal efficacy against Aspergillus niger and Fusarium oxysporum in terms of radial growth, sporulation, ultrastructural modifications, and phospholipid content of the fungal strains using a modified poisoned food technique, spore-germination slide bioassay, environmental scanning electron microscopy (ESEM), and spectrometry. SNPs expressed promising inhibitory effect on fungal growth and sporulation and also significantly reduced phospholipid content. © Springer-Verlag 2011

  10. Enhanced osteoblast responses to poly ether ether ketone surface modified by water plasma immersion ion implantation.

    Science.gov (United States)

    Wang, Heying; Lu, Tao; Meng, Fanhao; Zhu, Hongqin; Liu, Xuanyong

    2014-05-01

    Poly ether ether ketone (PEEK) offers a set of characteristics superior for human implants; however, its application is limited by the bio-inert surface property. In this work, PEEK surface was modified using single step plasma immersion ion implantation (PIII) treatment with a gas mixture of water vapor as a plasma resource and argon as an ionization assistant. Field emission scanning electron microscopy, atomic force microscopy and X-ray photoelectron spectroscopy were used to investigate the microstructure and composition of the modified PEEK surface. The water contact angle and zeta-potential of the surfaces were also measured. Osteoblast precursor cells MC3T3-E1 and rat bone mesenchymal stem cells were cultured on the PEEK samples to evaluate their cytocompatibility. The obtained results show that the hydroxyl groups as well as a "ravined structure" are constructed on water PIII modified PEEK. Compared with pristine PEEK, the water PIII treated PEEK is more favorable for osteoblast adhesion, spreading and proliferation, besides, early osteogenic differentiation indicated by the alkaline phosphatase activity is also up-regulated. Our study illustrates enhanced osteoblast responses to the PEEK surface modified by water PIII, which gives positive information in terms of future biomedical applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Influence of surface modified dental implant abutments on connective tissue attachment: A systematic review.

    Science.gov (United States)

    Blázquez-Hinarejos, Mónica; Ayuso-Montero, Raúl; Jané-Salas, Enric; López-López, José

    2017-08-01

    Determine whether surface modified prosthetic abutments for dental implants influence connective tissue attachment to the implant-abutment system. A systematic review was conducted using the MEDLINE-PubMed database, with two independent reviewers filtering the titles and abstracts. Two reviewers assessed all potentially relevant articles. An assessment was carried out on the level of evidence of the research according to the guidelines of the Oxford Centre for Evidence-Based Medicine (OCEBM). After an initial search, 109 potentially relevant articles were found. After reading the titles and abstracts, 99 articles were excluded because the surface treatment was limited to the implant and not to the abutment, or because different materials were analysed instead of surface treatments; 28 were also duplicate articles. An additional 6 research studies were included that were of interest and were found by reading the references of the included articles. The studies included are: 7 in vitro studies, 5 experimental studies in animals, 2 clinical trials in humans and 2 clinical cases. Surface modification for prosthetic abutments on dental implants can achieve connective tissue attachment to the abutment; however, more studies should be conducted in humans to obtain more and better evidence of these results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Nanostructured lipid carrier surface modified with Eudragit RS 100 and its potential ophthalmic functions

    Science.gov (United States)

    Zhang, Wenji; Li, Xuedong; Ye, Tiantian; Chen, Fen; Yu, Shihui; Chen, Jianting; Yang, Xinggang; Yang, Na; Zhang, Jinsong; Liu, Jinlu; Pan, Weisan; Kong, Jun

    2014-01-01

    This study was carried out to evaluate the ocular performance of a cationic Eudragit (EDU) RS 100-coated nanostructured lipid carrier (NLC). The genistein encapsulated NLC (GEN-NLC) was produced using the melt-emulsification technique followed by surface absorption of EDU RS 100. The EDU RS 100 increased the surface zeta potential from −7.46 mV to +13.60 mV, by uniformly forming a spherical coating outside the NLC surface, as shown by transmission electron microscopy images. The EDU RS 100 on the NLC surface effectively improved the NLC stability by inhibiting particle size growth. The obtained EDU RS 100-GEN-NLC showed extended precorneal clearance and a 1.22-fold increase in AUC (area under the curve) compared with the bare NLC in a Gamma scintigraphic evaluation. The EDU RS 100 modification also significantly increased corneal penetration producing a 3.3-fold increase in apparent permeability coefficients (Papp) compared with references. Draize and cytotoxicity testing confirmed that the developed EDU RS 100-GEN-NLC was nonirritant to ocular tissues and nontoxic to corneal cells. These results indicate that the NLC surface modified by EDU RS 100 significantly improves the NLC properties and exhibits many advantages for ocular use. PMID:25246787

  13. Retention of in-situ surface modified silica nanoparticles for carbon dioxide foam stabilization in sandpack

    Science.gov (United States)

    Adil, Muhammad

    2014-10-01

    Nanoparticle-stabilized CO2 foams have been used for mobility control for CO2 flooding; however, raw nanosilica particles which are hydrophilic in nature tend to develop unstable CO2 foam under certain reservoir conditions. The unstable foam leads to particles aggregation resulting in complete retention while propagating in a long distance, deep into the reservoir. This can be avoided by the application of a particular coating of a specific surfactant, polymer or their combination to the surface of the nanoparticles. The in-situ surface activation of unmodified SiO2 nanoparticles by interaction with mixed surfactant (TX100:SDBS) in aqueous media has been studied with extensive experiments using variable volumetric ratios. The retention of in-situ surface-modified nanoparticles was evaluated by the injection of the dispersion of nanoparticles through a sandpack. The loading of nanoparticles in dispersion was ranging from concentrated (5 wt %) to dilute (0.1 wt %). Effluent nanoparticles concentration histories were measured to determine the retained particles in the sandpack. Little retention (injected over two pore volumes) was attained for 0.5% SiO2 and volumetric ratio of 2:1 (TX100:SDBS). These results were concluded in terms of surface charges, adsorption isotherm, surface adsorption, and DLVO theory between particles and rock.

  14. Surface-modified nanoparticles as a new, versatile, and mechanically robust nonadhesive coating : Suppression of protein adsorption and bacterial adhesion

    NARCIS (Netherlands)

    Holmes, P. F.; Currie, E. P. K.; Thies, J. C.; van der Mei, H. C.; Busscher, H. J.; Norde, W.

    2009-01-01

    The synthesis of surface-modified silica nanoparticles, chemically grafted with acrylate and poly(ethylene glycol) (PEG) groups, and the ability of the resulting crosslinked coatings to inhibit protein adsorption and bacterial adhesion are explored. Water contact angles, nanoindentation, and atomic

  15. Improvement of epoxy resin properties by incorporation of TiO2 nanoparticles surface modified with gallic acid esters

    International Nuclear Information System (INIS)

    Radoman, Tijana S.; Džunuzović, Jasna V.; Jeremić, Katarina B.; Grgur, Branimir N.; Miličević, Dejan S.; Popović, Ivanka G.; Džunuzović, Enis S.

    2014-01-01

    Highlights: • Nanocomposites of epoxy resin and TiO 2 nanoparticles surface modified with gallates. • The T g of epoxy resin was increased by incorporation of surface modified TiO 2 . • WVTR of epoxy resin decreased in the presence of surface modified TiO 2 nanoparticles. • WVTR of nanocomposites was reduced with increasing gallates hydrophobic chain length. • Modified TiO 2 nanoparticles react as oxygen scavengers, inhibiting steel corrosion. - Abstract: Epoxy resin/titanium dioxide (epoxy/TiO 2 ) nanocomposites were obtained by incorporation of TiO 2 nanoparticles surface modified with gallic acid esters in epoxy resin. TiO 2 nanoparticles were obtained by acid catalyzed hydrolysis of titanium isopropoxide and their structural characterization was performed by X-ray diffraction and transmission electron microscopy. Three gallic acid esters, having different hydrophobic part, were used for surface modification of the synthesized TiO 2 nanoparticles: propyl, hexyl and lauryl gallate. The gallate chemisorption onto surface of TiO 2 nanoparticles was confirmed by Fourier transform infrared and ultraviolet–visible spectroscopy, while the amount of surface-bonded gallates was determined using thermogravimetric analysis. The influence of the surface modified TiO 2 nanoparticles, as well as the length of hydrophobic part of the gallate used for surface modification of TiO 2 nanoparticles, on glass transition temperature, barrier, dielectric and anticorrosive properties of epoxy resin was investigated by differential scanning calorimetry, water vapor transmission test, dielectric spectroscopy, electrochemical impedance spectroscopy and polarization measurements. Incorporation of surface modified TiO 2 nanoparticles in epoxy resin caused increase of glass transition temperature and decrease of the water vapor permeability of epoxy resin. The water vapor transmission rate of epoxy/TiO 2 nanocomposites was reduced with increasing hydrophobic part chain length of

  16. Understanding long-term silver release from surface modified porous titanium implants.

    Science.gov (United States)

    Shivaram, Anish; Bose, Susmita; Bandyopadhyay, Amit

    2017-08-01

    Prevention of orthopedic device related infection (ODRI) using antibiotics has met with limited amount of success and is still a big concern during post-surgery. As an alternative, use of silver as an antibiotic treatment to prevent surgical infections is being used due to the well-established antimicrobial properties of silver. However, in most cases silver is used in particulate form with wound dressings or with short-term devices such as catheters but not with load-bearing implants. We hypothesize that strongly adherent silver to load-bearing implants can offer longer term solution to infection in vivo. Keeping that in mind, the focus of this study was to understand the long term release study of silver ions for a period of minimum 6months from silver coated surface modified porous titanium implants. Implants were fabricated using a LENS™ system, a powder based additive manufacturing technique, with at least 25% volume porosity, with and without TiO 2 nanotubes in phosphate buffer saline (pH 7.4) to see if the total release of silver ions is within the toxic limit for human cells. Considering the fact that infection sites may reduce the local pH, silver release was also studied in acetate buffer (pH 5.0) for a period of 4weeks. Along with that, the osseointegrative properties as well as cytotoxicity of porous titanium implants were assessed in vivo for a period of 12weeks using a rat distal femur model. In vivo results indicate that porous titanium implants with silver coating show comparable, if not better, biocompatibility and bonding at the bone-implant interface negating any concerns related to toxicity related to silver to normal cells. The current research is based on our recently patented technology, however focused on understanding longer-term silver release to mitigate infection related problems in load-bearing implants that can even arise several months after the surgery. Prevention of orthopedic device related infection using antibiotics has met

  17. Effects of various surfactants on the dispersion stability and electrical conductivity of surface modified graphene

    Energy Technology Data Exchange (ETDEWEB)

    Uddin, Md. Elias [WCU Program, Department of BIN Fusion Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Kuila, Tapas [Surface Engineering and Tribology, CSIR – Central Mechanical Engineering Research Institute, Durgapur 721 302 (India); Nayak, Ganesh Chandra [Department of Applied Chemistry, ISM Dhanbad, Dhanbad 826 004, Jharkhand (India); Kim, Nam Hoon [Department of Hydrogen and Fuel Cell Engineering, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Ku, Bon-Cheol [Institute of Advanced Composite Materials, Korea Institute of Science and Technology, Dunsan-ri, Bongdong-eup, Wanju-gun, Jeollabuk-do 864-9 (Korea, Republic of); Lee, Joong Hee, E-mail: jhl@chonbuk.ac.kr [WCU Program, Department of BIN Fusion Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Department of Hydrogen and Fuel Cell Engineering, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of)

    2013-06-15

    Highlights: ► Water dispersible graphene has been prepared using ionic and non-ionic surfactants. ► XPS and FTIR spectra analysis confirm surface modification and reduction of GO. ► The highest water dispersibility is observed in the graphene modified with of SDBS. ► The best properties of modified graphene is achieved with GO/surfactant ratio of two. -- Abstract: Ionic and non-ionic surfactant functionalized, water dispersible graphene were prepared to investigate the effects on the dispersion stability and electrical conductivity of graphene. In this study, sodium dodecyl benzene sulfonate (SDBS), sodium dodecyl sulfate and 4-(1,1,3,3-tetramethylbutyl) phenyl-polyethylene glycol (Triton X-100) were used as ionic and non-ionic surfactants. The effects of surfactant concentrations on the dispersibility and electrical conductivity of the surface modified graphene were investigated. The dispersion stability of SDBS functionalized graphene (SDBS-G) was found to be best in water at 1.5 mg ml{sup −1}. X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy analysis indicate that the presence of surfactants does not prevent the reduction of graphene oxide (GO). These measurements also demonstrated that the surfactants were present on the surface of graphene, resulting in the formation of functionalized graphene. The thickness of different functionalized graphene was measured by Atomic force microscopy and varied significantly with different surfactants. The thermal properties of the functionalized graphene were also found to be dependent on the nature of the surfactants. The electrical conductivity of SDBS-G (108 S m{sup −1}) was comparatively higher than SDS and Triton X-100 functionalized graphene.

  18. Effects of various surfactants on the dispersion stability and electrical conductivity of surface modified graphene

    International Nuclear Information System (INIS)

    Uddin, Md. Elias; Kuila, Tapas; Nayak, Ganesh Chandra; Kim, Nam Hoon; Ku, Bon-Cheol; Lee, Joong Hee

    2013-01-01

    Highlights: ► Water dispersible graphene has been prepared using ionic and non-ionic surfactants. ► XPS and FTIR spectra analysis confirm surface modification and reduction of GO. ► The highest water dispersibility is observed in the graphene modified with of SDBS. ► The best properties of modified graphene is achieved with GO/surfactant ratio of two. -- Abstract: Ionic and non-ionic surfactant functionalized, water dispersible graphene were prepared to investigate the effects on the dispersion stability and electrical conductivity of graphene. In this study, sodium dodecyl benzene sulfonate (SDBS), sodium dodecyl sulfate and 4-(1,1,3,3-tetramethylbutyl) phenyl-polyethylene glycol (Triton X-100) were used as ionic and non-ionic surfactants. The effects of surfactant concentrations on the dispersibility and electrical conductivity of the surface modified graphene were investigated. The dispersion stability of SDBS functionalized graphene (SDBS-G) was found to be best in water at 1.5 mg ml −1 . X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy analysis indicate that the presence of surfactants does not prevent the reduction of graphene oxide (GO). These measurements also demonstrated that the surfactants were present on the surface of graphene, resulting in the formation of functionalized graphene. The thickness of different functionalized graphene was measured by Atomic force microscopy and varied significantly with different surfactants. The thermal properties of the functionalized graphene were also found to be dependent on the nature of the surfactants. The electrical conductivity of SDBS-G (108 S m −1 ) was comparatively higher than SDS and Triton X-100 functionalized graphene

  19. Speciation of uranium in surface-modified, hydrothermally treated, (UO2)2+-exchanged smectite clays

    International Nuclear Information System (INIS)

    Giaquinta, D.M.; Soderholm, L.; Yuchs, S.E.; Wasserman, S.R.

    1997-01-01

    A successful solution to the problem of disposal and permanent storage of water soluble radioactive species must address two issues: exclusion of the radionuclides from the environment and the prevention of leaching from the storage media into the environment. Immobilization of radionuclides in clay minerals has been studied. In addition to the use of clays as potential waste forms, information about the interactions of radionuclides with clays and how such interactions affect their speciations is crucial for successful modeling of actinide-migration. X-ray absorption spectroscopy (XAS) is used to determine the uranium speciation in exchanged and surface-modified clays. The XAS data from uranyl-loaded bentonite clay are compared with those obtained after the particle surfaces have been coated with alkylsilanes. These silane films, which render the surface of the clay hydrophobic, are added in order to minimize the ability of external water to exchange with the water in the clay interlayer, thereby decreasing the release rate of the exchanged-uranium species. Mild hydrothermal conditions are used in an effort to mimic potential geologic conditions that may occur during long-term radioactive waste storage. The XAS spectra indicate that the uranyl monomer species remain unchanged in most samples, except in those samples that were both coated with an alkylsilane and hydrothermally treated. When the clay was coated with an organic film, formed by the acidic deposition of octadecyltrimethoxysilane, hydrothermal treatment results in the formation of aggregated uranium species in which the uranium is reduced from U VI to U IV

  20. Gamma-ray burster counterparts - Radio

    International Nuclear Information System (INIS)

    Schaefer, B.E.; Cline, T.L.; Desai, U.D.

    1989-01-01

    Many observers and theorists have suggested that gamma-ray bursters (GRBs) are related to highly magnetized rotating, neutron stars, in which case an analogy with pulsars implies that GRBs would be prodigious emitters of polarized radio emission during quiescence. The paper reports on a survey conducted with the Very Large Array radio telescope of 10 small GRB error regions for quiescent radio emission at wavelengths of 2, 6, and 20 cm. The sensitivity of the survey varied from 0.1 to 0.8 mJy. The observations did indeed reveal four radio sources inside the GRB error regions. 27 refs

  1. Transport of surface-modified iron nanoparticle in porous media and application to arsenic(III) remediation

    International Nuclear Information System (INIS)

    Kanel, Sushil Raj; Nepal, Dhriti; Manning, Bruce; Choi, Heechul

    2007-01-01

    The surface-modified iron nanoparticles (S-INP) were synthesized, characterized and tested for the remediation of arsenite (As(III)), a well known toxic groundwater contaminant of concern. The S-INP material was fully dispersed in the aqueous phase with a particle size distribution of 2-10 nm estimated from high-resolution transmission electron microscopy (HR-TEM). X-ray photoelectron spectroscopy (XPS) revealed that an Fe(III) oxide surface film was present on S-INP in addition to the bulk zero-valent Fe 0 oxidation state. Transport of S-INP through porous media packed in 10 cm length column showed particle breakthroughs of 22.1, 47.4 and 60 pore volumes in glass beads, unbaked sand, and baked sand, respectively. Un-modified INP was immobile and aggregated on porous media surfaces in the column inlet area. Results using S-INP pretreated 10 cm sand-packed columns containing ∼2 g of S-INP showed that 100 % of As(III) was removed from influent solutions (flow rate 1.8 mL min -1 ) containing 0.2, 0.5 and 1.0 mg L -1 As(III) for 9, 7 and 4 days providing 23.3, 20.7 and 10.4 L of arsenic free water, respectively. In addition, it was found that 100% of As(III) in 0.5 mg/L solution (flow rate 1.8 mL min -1 ) was removed by S-INP pretreated 50 cm sand packed column containing 12 g of S-INP for more than 2.5 months providing 194.4 L of arsenic free water. Field emission scanning electron microscopy (FE-SEM) showed S-INP had transformed to elongated, rod-like shaped corrosion product particles after reaction with As(III) in the presence of sand. These results suggest that S-INP has great potential to be used as a mobile, injectable reactive material for in-situ sandy groundwater aquifer treatment of As(III)

  2. Influence of surface modified nanoilmenite/amorphous silica composite particles on the thermal stability of cold galvanizing coating

    Directory of Open Access Journals (Sweden)

    A.M. Al-Sabagh

    2018-03-01

    Full Text Available The present approach investigates the use of novel nanoilmenite/amorphous silica composite (NI/AS particles fabricated from ilmenite nanoparticles (FeTiO3 NPs and synthesized amorphous silica grains to improve thermal stability of the cold galvanizing coating. Transmission electron microscopic (TEM images demonstrated that both nanoilmenite and nanocomposite particles were of flaky-like nature and the average diameter of the particles is 20 nm. The lamellar shape of the nanocomposite and spherical nature of Zn-dust particles were illustrated by scanning electron microscopy (SEM micrographs. Different alkyd-based cold galvanizing coating formulations were modified using uniformly dispersing various amounts of the processed nanocomposite particles as a modifier to form some engineering nanocomposite coatings. Thermal stability of the nanocomposite and Zn-dust particles was determined by thermo-gravimetric analysis (TGA. From the obtained results it could be observed that the weight loss (% as a feature of the thermal stability in case of the nanocomposite particles was 2.9 compared to 85.9 for Zn-dust powder grains. Derivative thermo-gravimetric (DTG measurements were done under nitrogen atmosphere for the cured cold galvanizing coating samples heated from room temperature to 1000 °C. The obtained results revealed that the maximum decomposition temperature point in the third degradation step for 6% nanocomposite surface modified cured sample (CG-F was detected at 693 °C and was less value for unmodified conventional cold galvanizing coating (CG-A at 612 °C. The increase in thermal stability with increasing the concentration of nanocomposite particles could be mainly attributed to the interface surface interaction between the nanocomposite particles and alkyd resin matrix in which enhancing the inorganic-organic network stiffness by causing a reduction in the total free spaces and enhancement in the cross-linking density of the cured film

  3. Electrochromic coatings made of surface modified rutile and anatase pigments: Influence of trisilanol POSS dispersant on electrochromic effect

    International Nuclear Information System (INIS)

    Mihelčič, Mohor; Francetič, Vojmir; Pori, Pavli; Gradišar, Helena; Kovač, Janez; Orel, Boris

    2014-01-01

    Graphical abstract: - Highlights: • Transparent pigmented coatings were deposited from titania dispersions. • Trisilanol POSS was used as dispersant. • Surface modification of pigment particles was established from TEM, TG and IR. • IR spectra studies revealed covalent and H-bond dispersant/pigment interactions. • Electrochromic properties of titanina pigment coatings were shown and discussed. - Abstract: Polyhedral oligomeric silsesqioxanes (POSS) compounds consisting of [RSiO 3/2 ] n groups organized in the form of various polyhedra (T n , n = 3, 6, 8, 10, 12, ….) have not often been used as pigment surface modifiers. Their interactions with pigments are not known in detail and coatings deposited from pigments modified by POSS dispersants are rare. Identification of interactions between a dispersant and the surface of pigments is important from the point of view of obtaining stable pigment dispersions enabling the deposition of optical coatings with high pigment loading, low haze and mechanical integrity. Thin TiO 2 (anatase) pigment coatings (70–260 nm) were deposited from pigment dispersions prepared by milling metatitanic acid (mTiA) powder agglomerates with trisilanol heptaisobutyl silsesquioxane dispersant (trisilanol POSS) in butanol and hexane. The results of TEM, EDAX and TG measurements confirmed the influence of trisilanol POSS dispersant on the formation of a dispersion with a uniform distribution of mTiA and rutile (mTiR) nanoparticles with a size of about 30 ± 5.0 nm and 90 ± 5.0 nm, respectively, as determined from dynamic light scattering (DLS) measurements. The mTiA/trisilanol POSS dispersions with added titanium tetraisopropoxide were deposited on fluorine-doped tin oxide (FTO) coated glass (spin-coating) and indium tin oxide coated polymeric substrate (ITO PET) (coil-coating) and thermally treated at 150 °C. UV–vis spectra, AFM and SEM results showed that the pigment coatings exhibited low haze (up to 6%), low surface

  4. In vitro and in vivo anticancer activity of surface modified paclitaxel attached hydroxyapatite and titanium dioxide nanoparticles.

    Science.gov (United States)

    Venkatasubbu, G Devanand; Ramasamy, S; Reddy, G Pramod; Kumar, J

    2013-08-01

    Targeted drug delivery using nanocrystalline materials delivers the drug at the diseased site. This increases the efficacy of the drug in killing the cancer cells. Surface modifications were done to target the drug to a particular receptor on the cell surface. This paper reports synthesis of hydroxyapatite and titanium dioxide nanoparticles and modification of their surface with polyethylene glycol (PEG) followed by folic acid (FA). Paclitaxel, an anticancer drug, is attached to functionalized hydroxyapatite and titanium dioxide nanoparticles. The pure and functionalised nanoparticles are characterised with XRD, TEM and UV spectroscopy. Anticancer analysis was carried out in DEN induced hepatocarcinoma animals. Biochemical, hematological and histopathological analysis show that the surface modified paclitaxel attached nanoparticles have an higher anticancer activity than the pure paclitaxel and surface modified nanoparticles without paclitaxel. This is due to the targeting of the drug to the folate receptor in the cancer cells.

  5. Synthesis and Characterization of Surface Modified, Fluorescent and Biocompatible ZnS Nanoparticles with a Hydrophobic Chitosan Derivative.

    Science.gov (United States)

    Jothimani, B; Sureshkumar, S; Venkatachalapathy, B

    2017-07-01

    The introduction of a hydrophobic moiety on chitosan enhances the self-assembling properties, mucoadhesion, the permeability of the macromolecule and aids in target specific delivery. Our group synthesized a hydrophobic trans N-(6,6-Dimethyl-2-hepten-4-ynyl)chitosan derivative (CSD) and studied the surface modification of ZnS nanoparticles in a single pot reaction. X-ray diffraction studies and FESEM imaging confirms the nano size and morphology of the surface modified Zinc sulfide nanoparticles (ZnS-CSD NPs). The proposed ZnS-CSD NPs showed excellent emission at 457 nm. Photostability studies indicate that the surface modified ZnS-CSD NPs possess better photostability than Rhodamine B and FITC. Cell viability tests confirmed the biocompatibility of the modified nanoparticles. All these features of ZnS- CSD NPs makes these candidates an excellent choice in a wide range of in vitro or in vivo studies as fluorescent biological labels.

  6. The influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages

    OpenAIRE

    Correia, Clara R.; Gaifem, Joana; Oliveira, Mariana Braga; Silvestre, Ricardo Jorge Leal; Mano, J. F.

    2017-01-01

    Macrophages play a crucial role in the biological performance of biomaterials, as key factors in defining the optimal inflammation-healing balance towards tissue regeneration and implant integration. Here, we investigate how different surface modifications performed on poly(L-lactic acid) (PLLA) films would influence the differentiation of human monocytes into macrophages. We tested PLLA films without modification, surface-modified by plasma treatment (pPLLA) or by combining plasma treatment ...

  7. The influence of the addition of dye surface modifier on the performance of transparent dye sensitized solar cells

    Science.gov (United States)

    Rosa, Erlyta Septa; Shobih, Retnaningsih, Lilis; Muliani, Lia; Hidayat, Jojo

    2017-11-01

    The light-harvesting properties and charge injection kinetics of dye molecules play a significant role to improve the performance of dye-sensitized solar cells (DSSC). Dyes based on metal complexes with ruthenium complexes also a variety of metal-organic dyes such as Zn-porphyrin derivatives have been used. The requirements for dye to function as a photosensitizer in DSSC are the absorption in the visible or near-infrared regions of the solar spectrum and the binding to the semiconductor TiO2. In order to interact with the TiO2 surface it is preferable that the dye has a functional group as anchoring group such as carboxylic or other peripheral acidic. The carboxylic group is the most frequently used anchoring group, as in ruthenium-complex based dyes. However, carboxylic acid as an anchoring group is still not enough for conducting in electron injection to TiO2. In this research, 0.87 mg phosphonic acid is added to N719 and Z907 ruthenium-complex based dyes, rspectively, as a surface modifier to strengthen the anchoring group. The addition of dyes surface modifier on the transparent DSSC device performance is investigated. Under illumination of 500 Wm-2, the power conversion efficiency (PCE) of DSSC using N719 ruthenium increases from 2.09 % to 3.22 % by the addition of surface modifier. However, different results are obtained on Z907 dye, where efficiency decreases from 2.02 % to 1.58 %.

  8. Heterogeneous freezing of droplets with immersed surface modified mineral dust particles

    Science.gov (United States)

    Hartmann, Susan

    2010-05-01

    In the framework of the international measurement campaign FROST II (FReezing Of duST), the heterogeneous freezing of droplets with an immersed surface modified size-segregated mineral dust particles was investigated at LACIS (Leipzig Aerosol Cloud Interaction Simulator, Stratmann et al. 2004). The following measurements were done: LACIS, CFDC (Continuous Flow thermal gradient Diffusion Chamber, Rogers (1988)) and FINCH (Fast Ice Nucleus Chamber Counter, Bundke et al (2008)) were used to analyze the immersion freezing behavior of the treated Arizona Test Dust (ATD) particles at different temperature regimes. The ability to act as IN (Ice Nucleus) in the deposition nucleation mode was quantified by the PINC (Portable Ice Nucleation Chamber) and the CFDC instrument. AMS (Aerosol Mass Spectrometers, e.g. Schneider et al. (2005)) and ATOFMS (Aerosol Time-Of-Flight Mass Spectrometer) measurements were applied to determine particle composition. The hygroscopic growth and the critical super-saturations needed for droplet activation were determined by means of an H-TDMA (Humidity-Tandem Differential Mobility Analyzer) and CCN counter (Cloud Condensation Nucleus counter, Droplet Measurement Technologies, Roberts and Nenes (2005)). The 300 nm ATD particles were chemically and physically treated by coating with sulphuric acid (H2SO4, three different coating thicknesses) and ammonium sulphate ((NH4)2SO4) or by thermal treatment with a thermodenuder operating at 250°C. The H2SO4 coating modified the particles by reacting with particle material, forming soluble sulfates and therefore changing surface properties. AMS showed free H2SO4 only for thick H2SO4 coatings. In the heated section of the thermodenuder coating materials were evaporated partly and the surface properties of the particles were additionally altered. Uncoated particles and those coated with thin coatings of H2SO4, showed almost no hygroscopic growth. Particles coated with thicker coatings of H2SO4 and of (NH4

  9. Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective.

    Science.gov (United States)

    Darwiche, Walaa; Gubler, Brigitte; Marolleau, Jean-Pierre; Ghamlouch, Hussein

    2018-01-01

    Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of small mature-looking CD19+ CD23+ CD5+ B-cells that accumulate in the blood, bone marrow, and lymphoid organs. To date, no consensus has been reached concerning the normal cellular counterpart of CLL B-cells and several B-cell types have been proposed. CLL B-cells have remarkable phenotypic and gene expression profile homogeneity. In recent years, the molecular and cellular biology of CLL has been enriched by seminal insights that are leading to a better understanding of the natural history of the disease. Immunophenotypic and molecular approaches (including immunoglobulin heavy-chain variable gene mutational status, transcriptional and epigenetic profiling) comparing the normal B-cell subset and CLL B-cells provide some new insights into the normal cellular counterpart. Functional characteristics (including activation requirements and propensity for plasma cell differentiation) of CLL B-cells have now been investigated for 50 years. B-cell subsets differ substantially in terms of their functional features. Analysis of shared functional characteristics may reveal similarities between normal B-cell subsets and CLL B-cells, allowing speculative assignment of a normal cellular counterpart for CLL B-cells. In this review, we summarize current data regarding peripheral B-cell differentiation and human B-cell subsets and suggest possibilities for a normal cellular counterpart based on the functional characteristics of CLL B-cells. However, a definitive normal cellular counterpart cannot be attributed on the basis of the available data. We discuss the functional characteristics required for a cell to be logically considered to be the normal counterpart of CLL B-cells.

  10. Effect of surface modified TiO2 nanoparticles on thermal, barrier and mechanical properties of long oil alkyd resin-based coatings

    OpenAIRE

    T. S. Radoman; J. V. Dzunuzovic; K. T. Trifkovic; T. Palija; A. D. Marinkovic; B. Bugarski; E. S. Dzunuzovic

    2015-01-01

    Novel soy alkyd-based nanocomposites (NCs) were prepared using TiO2 nanoparticles (NPs) surface modified with different gallates, and for the first time with imine obtained from 3,4-dihydroxybenzaldehyde and oleylamine (DHBAOA). Unmodified and surface modified anatase TiO2 NPs were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and ultraviolet-visible (UV-Vis) spectroscopy, while the amount of adsorbed ligands w...

  11. Growth and Functionality of Cells Cultured on Conducting and Semi-Conducting Surfaces Modified with Self-Assembled Monolayers (SAMs

    Directory of Open Access Journals (Sweden)

    Rajendra K. Aithal

    2016-02-01

    Full Text Available Bioengineering of dermal and epidermal cells on surface modified substrates is an active area of research. The cytotoxicity, maintenance of cell phenotype and long-term functionality of human dermal fibroblast (HDF cells on conducting indium tin oxide (ITO and semi-conducting, silicon (Si and gallium arsenide (GaAs, surfaces modified with self-assembled monolayers (SAMs containing amino (–NH2 and methyl (–CH3 end groups have been investigated. Contact angle measurements and infrared spectroscopic studies show that the monolayers are conformal and preserve their functional end groups. Morphological analyses indicate that HDFs grow well on all substrates except GaAs, exhibiting their normal spindle-shaped morphology and exhibit no visible signs of stress or cytoplasmic vacuolation. Cell viability analyses indicate little cell death after one week in culture on all substrates except GaAs, where cells died within 6 h. Cells on all surfaces proliferate except on GaAs and GaAs-ODT. Cell growth is observed to be greater on SAM modified ITO and Si-substrates. Preservation of cellular phenotype assessed through type I collagen immunostaining and positive staining of HDF cells were observed on all modified surfaces except that on GaAs. These results suggest that conducting and semi-conducting SAM-modified surfaces support HDF growth and functionality and represent a promising area of bioengineering research.

  12. Human procollagen type I surface-modified PHB-based non-woven textile scaffolds for cell growth: preparation and short-term biological tests.

    Science.gov (United States)

    Kawalec, Michał; Sitkowska, Anna; Sobota, Michał; Sieroń, Aleksander L; Komar, Patrycja; Kurcok, Piotr

    2014-10-30

    3D fine porous structures obtained by electrospinning a poly[(R,S)-3-hydroxybutyrate] (aPHB)/ poly[(R)-3-hydroxybutyrate] (PHB) (85/15 w/w) blend were successfully modified with human procollagen type I by simple immersion of the polyester scaffold in an aqueous solution of the protein. Effective modification of the scaffold with human procollagen I was confirmed by an immunodetection test, which revealed the presence of the procollagen type I as an outer layer even on inner structures of the porous matrixes. Biological tests of 3D fabrics made of the PHB blend provide support for the adhesion and proliferation of human fibroblasts, while their modification with procollagen type I increased the biocompatibility of the final scaffolds significantly, as shown by the notable increase in the number of attached cells during the early hours of their incubation. Based on these findings, human procollagen type I surface-modified aPHB/PHB scaffolds should be considered a promising material in regenerative medicine.

  13. Optical, thermal and combustion properties of self-colored polyamide nanocomposites reinforced with azo dye surface modified ZnO nanoparticles

    Science.gov (United States)

    Hajibeygi, Mohsen; Shabanian, Meisam; Omidi-Ghallemohamadi, Mehrdad; Khonakdar, Hossein Ali

    2017-09-01

    New self-colored aromatic-polyamide (PA) nanocomposites containing azo and naphthalene chromophores were prepared with azo-dye surface-modified ZnO nanoparticles (SMZnO) using solution method in dimethylformamide. The X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) results showed the uniform distribution for ZnO nanoparticles in the PA matrix. The UV-vis spectra of PA/ZnO nanocomposites (PANC) showed a blue shift as well as reduction in absorbance intensities and the photoluminescence studies revealed that the increasing intensities of the violet emission in SMZnO loading. From thermo gravimetric analysis (TGA), the temperature at 10% mass loss (T10) increased from 291.8 °C to 387.6 °C for PANC containing 8 mass% of SMZnO, as well as the char yield enhanced significantly, which was about 23.5% higher than the neat PA. The peak heat release rate resulted from microscale combustion calorimeter (MCC), by 8 mass% loading of SMZnO, decreased about 56.9% lower than the neat PA.

  14. Mechanical, Thermal Degradation, and Flammability Studies on Surface Modified Sisal Fiber Reinforced Recycled Polypropylene Composites

    Directory of Open Access Journals (Sweden)

    Arun Kumar Gupta

    2012-01-01

    Full Text Available The effect of surface treated sisal fiber on the mechanical, thermal, flammability, and morphological properties of sisal fiber (SF reinforced recycled polypropylene (RPP composites was investigated. The surface of sisal fiber was modified with different chemical reagent such as silane, glycidyl methacrylate (GMA, and O-hydroxybenzene diazonium chloride (OBDC to improve the compatibility with the matrix polymer. The experimental results revealed an improvement in the tensile strength to 11%, 20%, and 31.36% and impact strength to 78.72%, 77%, and 81% for silane, GMA, and OBDC treated sisal fiber reinforced recycled Polypropylene (RPP/SF composites, respectively, as compared to RPP. The thermogravimetric analysis (TGA, differential scanning calorimeter (DSC, and heat deflection temperature (HDT results revealed improved thermal stability as compared with RPP. The flammability behaviour of silane, GMA, and OBDC treated SF/RPP composites was studied by the horizontal burning rate by UL-94. The morphological analysis through scanning electron micrograph (SEM supports improves surface interaction between fiber surface and polymer matrix.

  15. Electrochromism in surface modified crystalline WO3 thin films grown by reactive DC magnetron sputtering

    Science.gov (United States)

    Karuppasamy, A.

    2013-10-01

    In the present work, tungsten oxide thin films were deposited at various oxygen chamber pressures (1.0-5.0 × 10-3 mbar) by maintaining the sputtering power density and argon pressure constant at 3.0 W/cm2 and 1.2 × 10-2 mbar, respectively. The role of surface morphology and porosity on the electrochromic properties of crystalline tungsten oxide thin films has been investigated. XRD and Raman studies reveal that all the samples post annealed at 450 ̊C in air for 3.0 h settle in monoclinic crystal system of tungsten oxide (W18O49). Though the phase of material is indifferent to oxygen pressure variations (PO2), morphology and film density shows a striking dependence on PO2. A systematic study on plasma (OES), morphology, optical and electrochromic properties of crystalline tungsten oxide reveal that the films deposited at PO2 of 2.0 × 10-3 mbar exhibit better coloration efficiency (58 cm2/C), electron/ion capacity (Qc: -25 mC/cm2), and reversibility (92%). This is attributed to the enhanced surface properties like high density of pores and fine particulates (100 nm) and to lesser bulk density of the film (ρ/ρo = 0.84) which facilitates the process of intercalation/de-intercalation of protons and electrons. These results show good promise toward stable and efficient crystalline tungsten oxide based electrochromic device applications.

  16. A possible human counterpart of the principle of increasing entropy

    International Nuclear Information System (INIS)

    Liang, Y.; An, K.N.; Yang, G.; Huang, J.P.

    2014-01-01

    It is well-known that the principle of increasing entropy holds for isolated natural systems that contain non-adaptive molecules. Here we present, for the first time, an experimental evidence for a possible human counterpart of the principle in an isolated social system that involves adaptive humans. Our work shows that the human counterpart is valid even though interactions among humans in social systems are distinctly different from those among molecules in natural systems. Thus, it becomes possible to understand social systems from this natural principle, at least to some extent.

  17. Antibacterial and microstructure properties of titanium surfaces modified with Ag-incorporated nanotube arrays

    Energy Technology Data Exchange (ETDEWEB)

    Li, Guangzhong; Cheng, Li [State Key Laboratory of Porous Metal Materials, Northwest Institute for Nonferrous Metal Research (China); Yang, Hui-lin [Department of Orthopaedics, Wuxi People' s Hospital, Nanjing Medical University, Jiangsu Province (China); Zhao, Quan-ming, E-mail: abc8385@163.com [Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou (China)

    2016-07-15

    Although titanium (Ti) and its alloys have been widely used as implants in clinical settings, failures still occur mainly due to poor bioactivity and implant-associated infections. Here, we coated Ti implants with TiO{sub 2} nanotubes (TNTs) incorporated with the antibacterial agent Ag to produce Ag-TNTs, through anodization in AgNO{sub 3} and xenon light irradiation. We characterized surface morphology and composition of the coating with scanning electron microscopy (SEM) and X-ray diffraction (XRD), respectively. We investigated surface topography of the coatings by atomic force microscopy (AFM) operated in the tapping mode. The results indicate that Ag was successfully doped onto the TNTs, and that the nanoparticles were mainly distributed on the surface of TNTs. Finally, our antibacterial experiments reveal that Ag-TNTs on Ti implants exhibit excellent antibacterial activities, which promises to have significant clinical applications as implants. (author)

  18. 76 FR 61090 - Endangered and Threatened Species; Counterpart Regulations

    Science.gov (United States)

    2011-10-03

    ..., National Fire Plan Counterpart Regulation Alternative Consultation Agreements (ACAs). DATES: This is effective on October 1, 2011. ADDRESSES: The final decision of revocation is available on the internet at http://www.nmfs.noaa.gov/pr/laws/esa/policies.htm#consultation and http://www.fws.gov/endangered/esa...

  19. Search for infrared counterparts of gamma-ray bursters

    International Nuclear Information System (INIS)

    Schaefer, B.E.; Cline, T.L.

    1985-01-01

    The result of two searches for infrared counterparts of Gamma-ray Bursters (GRB's) is reported. The first search was made using data from the Infrared Astronomy Satellite and covered 23 positions. The second search was made with the Kitt Peak 1.5 m telescope and covered 3 positions. In neither of these two searches was any infrared candidate detected

  20. Dynamic shear rheology of colloidal suspensions of surface-modified silica nanoparticles in PEG

    Science.gov (United States)

    Swarna; Pattanayek, Sudip Kumar; Ghosh, Anup Kumar

    2018-03-01

    The present work illustrates the effect of surface modification of silica nanoparticles (500 nm) with 3-(glycidoxypropyl)trimethoxy silane which was carried out at different reaction times. The suspensions prepared from modified and unmodified silica nanoparticles were evaluated for their shear rate-dependent viscosity and strain-frequency-dependent modulus. The linear viscoelastic moduli, viz., storage modulus and loss modulus, were compared with those of nonlinear moduli. The shear-thickened suspensions displayed strain thinning at low-frequency smaller strains and a strong strain overshoot at higher strains, characteristics of a continuous shear thickening fluids. The shear-thinned suspension, conversely, exhibited a strong elastic dominance at smaller strains, but at higher strains, its strain softened observed in the steady shear viscosity plot indicating characteristics of yielding material. Considering higher order harmonic components, the decomposed elastic and viscous stress revealed a pronounced elastic response up to 10% strain and a high viscous damping at larger strains. The current work is one of a kind in demonstrating the effect of silica surface functionalization on the linear and nonlinear viscoelasticity of suspensions showing a unique rheological fingerprint. The suspensions can thus be predicted through rheological studies for their applicability in energy absorbing and damping materials with respect to their mechanical properties.

  1. Characterization and Hydrogen Storage of Surface-Modified Multiwalled Carbon Nanotubes for Fuel Cell Application

    Directory of Open Access Journals (Sweden)

    Kuen-Song Lin

    2012-01-01

    Full Text Available The synthesis, identification, and H2 storage of multiwalled carbon nanotubes (MWCNTs have been investigated in the present work. MWCNTs were produced from the catalytic-assembly solvent (benzene-thermal (solvothermal route. Reduction of C6Cl6 with metallic potassium was carried out in the presence of Co/Ni catalyst precursors at 503–623 K for 12 h. XRD patterns indicated that the abstraction of Cl from hexachlorobenzene and the formation of KCl precipitates were involved in the early stage of the synthesis process of MWCNTs. This result offers further explanation for the formation of MWCNT structure and yield using the solvothermal route depending on the Co/Ni catalyst precursors. The diameter of MWCNTs ranged between 30 and 100 nm and the H2 storage capacity of MWCNTs improved when 2.7–3.8 wt% Pd or NaAlH4 were doped. The XANES/EXAFS spectra revealed that the Co/Ni catalyst precursors of the MWCNT synthesis were in metallic form and Pd atoms possessed a Pd–Pd bond distance of 2.78 Å with a coordination number of 9.08. Ti-NaAlH4 or Pd nanoparticles were dispersed on MWCNTs and facilitated to improve the H2 storage capacity significantly with the surface modification process.

  2. Slurry Erosion Studies on Surface Modified 13Cr-4Ni Steels: Effect of Angle of Impingement and Particle Size

    Science.gov (United States)

    Manisekaran, T.; Kamaraj, M.; Sharrif, S. M.; Joshi, S. V.

    2007-10-01

    Hydroturbine steels, such as 13Cr-4Ni martensitic steels, are generally subjected to heavy-erosive wear and loss of efficiency due to solid particulate entrainment in the water. Surface-modified steels have proven to give better performance in terms of erosive wear resistance. In the present study, an attempt is made to investigate the effect of angle of impingement and particle size on slurry-jet erosion behavior of pulsed plasma nitrided and laser hardened 13Cr-4Ni steels. Laser hardening process has shown good performance at all angles of impingement due to martensitic transformation of retained austenite. Plastic deformation mode of material removal was also an evident feature of all laser-hardened surface damage locations. However, pulsed-plasma nitrided steels have exhibited chip formation and micro-cutting mode of erosive wear. Erosion with 150-300 μm size was twice compared to 150 μm size slurry particulates.

  3. Deposition of phospholipid layers on SiO{sub 2} surface modified by alkyl-SAM islands

    Energy Technology Data Exchange (ETDEWEB)

    Tero, R.; Takizawa, M.; Li, Y.J.; Yamazaki, M.; Urisu, T

    2004-11-15

    Formation of the supported planar bilayer of dipalmitoylphosphatidylcholine (DPPC) on SiO{sub 2} surfaces modified with the self-assembled monolayer (SAM) of octadecyltrichlorosilane (OTS) has been investigated by atomic force microscopy (AFM). DPPC was deposited by the fusion of vesicles on SiO{sub 2} surfaces with OTS-SAM islands of different sizes and densities. The DPPC bilayer membrane formed self-organizingly on the SiO{sub 2} surface with small and sparse OTS islands, while did not when the OTS islands were larger and denser. The relative size between the vesicles and the SiO{sub 2} regions is the critical factor for the formation of the DPPC bilayer membrane.

  4. Uptake and toxic effects of surface modified nanomaterials in freshwater aquatic organisms

    Science.gov (United States)

    Seda, Brandon Casey

    Nanomaterials are a class of materials with unique properties due to their size, and the association of these properties with the toxicity of nanomaterials is poorly understood. The present study assessed the toxic effects of stable aqueous colloidal suspensions of three distinctly different classes of nanomaterials in aquatic organisms. The fullerene, C70, was stabilized through non-covalent surface modification with gallic acid. Toxicity of C70-gallic acid was confirmed to exhibit similar toxic effects as C60-fullerene, including changes in antioxidative processes in Daphnia magna. Daphnia magna fecundity was significantly reduced in 21d bioassays at C70-gallic concentrations below quantifiable limits (0.03 mg/L C70). Antioxidant enzyme activities of glutathione peroxidase and superoxide dismutase as well as lipid peroxidation suggested that exposed organisms experienced oxidative stress. Carbon dots are a class of nanomaterials proposed for use as nontoxic alternatives to semiconductor quantum dots for photoluminescent applications, because of the difference in toxicity of their core components: carbon as opposed to heavy metals. In vivo analysis of treated organisms by confocal fluorescence microscopy revealed carbon dots were absorbed and systemically distributed regardless of particle size. The present study did not find any evidence of acute toxicity at concentrations up to 10mg/L carbon dots. These concentrations also failed to produce negative effects in Ceriodaphnia dubia bioassays to predict chronic toxicity. Carbon dots also failed to elicit developmental toxic effects in zebrafish. The toxic effects of semiconductor quantum dots have been partially attributed to the release of heavy metals with their degradation, particularly cadmium. Laser ablation inductively coupled mass spectrometry was used to compare the uptake of cadmium, selenium and zinc in Daphnia magna treated to CdSe/ZnS quantum dots or CdCl2. These quantum dots were observed to accumulate

  5. In vitro behavior of human osteoblast-like cells (SaOS2) cultured on surface modified titanium and titanium-zirconium alloy

    Energy Technology Data Exchange (ETDEWEB)

    Chen Xiaobo [Centre for Material and Fibre Innovation, Institute for Technology Research and Innovation, Deakin University, Waurn Ponds, Victoria 3217 (Australia); CAST CRC, Department of Materials Engineering, Monash University, Wellington Road, Clayton, Victoria 3800 (Australia); Li Yuncang; Hodgson, Peter D. [Centre for Material and Fibre Innovation, Institute for Technology Research and Innovation, Deakin University, Waurn Ponds, Victoria 3217 (Australia); Wen Cuie, E-mail: cwen@swin.edu.au [IRIS, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology, ATC Building Burwood Road, Hawthorn, Victoria 3122 (Australia)

    2011-10-10

    In this study, titanium (Ti) and titanium-zirconium (TiZr) alloy samples fabricated through powder metallurgy were surface modified by alkali-heat treatment and calcium (Ca)-ion-deposition. The alteration of the surface morphology and the chemistry of the Ti and TiZr after surface modification were examined. The bioactivity of the Ti and TiZr alloys after the surface modification was demonstrated. Subsequently, the cytocompatibility of the surface modified Ti and TiZr was evaluated via in vitro cell culture using human osteoblast-like cells (SaOS2). The cellular attachment, adhesion and proliferation after cell culture for 14 days were characterized by scanning electron microscopy (SEM) and MTT assay. The relationship between surface morphology and chemical composition of the surface modified Ti and TiZr and cellular responses was investigated. Results indicated that the surface-modified Ti and TiZr alloys exhibited excellent in vitro cytocompatibility together with satisfactory bioactivity. Since osteoblast adhesion and proliferation are essential prerequisites for a successful implant in vivo, these results provide evidence that Ti and TiZr alloys after appropriate surface modification are promising biomaterials for hard tissue replacement. Highlights: {yields} Titanium (Ti) and titanium-zirconium (TiZr) alloy for load-bearing implant applications. {yields} Implant applications. {yields} Alkali-heat treatment and calcium (Ca)-ion-deposition as surface modification methods. {yields} Surface modified Ti and TiZr exhibited excellent biocompatibility and bioactivity.

  6. Benzene and superior counterpart; Benzene et homologues superieurs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    A century ago, the first case of purpura and acute anemia provoked by benzene was described. Afterwards, others important toxic effects in relation with the exposure to this solvent were known: medullar aplasia, acute leukemia,carcinogenesis. The chronic intoxication by benzene is called benzenism, the term of benzolism is devoted to the intoxication provoked by the mixture of benzene and superior counterparts: toluene, xylenes. (N.C.)

  7. OPTICAL COUNTERPARTS OF THE NEAREST ULTRALUMINOUS X-RAY SOURCES

    Energy Technology Data Exchange (ETDEWEB)

    Gladstone, Jeanette C.; Heinke, Craig O.; Cartwright, Taylor F. [Department of Physics, University of Alberta, 11322-89 Avenue, Edmonton, Alberta T6G 2G7 (Canada); Copperwheat, Chris [Department of Physics, Liverpool John Moores University, Wirral CH41 1LD (United Kingdom); Roberts, Timothy P. [Department of Physics, University of Durham, South Road, Durham DH1 3LE (United Kingdom); Levan, Andrew J. [Department of Physics, University of Warwick, Coventry CV4 7VL (United Kingdom); Goad, Mike R., E-mail: j.c.gladstone@ualberta.ca [Department of Physics and Astronomy, University of Leicester, University Road, Leicester LE1 7AL (United Kingdom)

    2013-06-01

    We present a photometric survey of the optical counterparts of ultraluminous X-ray sources (ULXs) observed with the Hubble Space Telescope (HST) in nearby ({approx}<5 Mpc) galaxies. Of the 33 ULXs with HST and Chandra data, 9 have no visible counterpart, placing limits on their M{sub V} of {approx} -4 to -9, enabling us to rule out O-type companions in 4 cases. The refined positions of two ULXs place them in the nucleus of their host galaxy. They are removed from our sample. Of the 22 remaining ULXs, 13 have one possible optical counterpart, while multiple are visible within the error regions of other ULXs. By calculating the number of chance coincidences, we estimate that 13 {+-} 5 are the true counterparts. We attempt to constrain the nature of the companions by fitting the spectral energy distribution and M{sub V} to obtain candidate spectral types. We can rule out O-type companions in 20 cases, while we find that one ULX (NGC 253 ULX2) excludes all OB-type companions. Fitting with X-ray irradiated models provides constraints on the donor star mass and radius. For seven ULXs, we are able to impose inclination-dependent upper and/or lower limits on the black holes' mass, if the extinction to the assumed companion star is not larger than the Galactic column. These are NGC 55 ULX1, NGC 253 ULX1, NGC 253 ULX2, NGC 253 XMM6, Ho IX X-1, IC342 X-1, and NGC 5204 X-1. This suggests that 10 ULXs do not have O companions, while none of the 18 fitted rule out B-type companions.

  8. Search for Gravitational Wave Counterparts with Fermi GBM

    Science.gov (United States)

    Hui, C. M.

    2017-01-01

    The progenitor of short gamma-ray bursts (GRBs) is believed to be the merger of two compact objects. This type of events will also produce gravitational waves. Since the gravitational waves discovery by LIGO, the search for a joint detection with an electromagnetic counterpart has been ongoing. Fermi GBM detects approximately 40 short GRBs per year, and we have been expanding our search looking for faint events in the GBM data that did not trigger onboard.

  9. Mesoporous bioactive glass surface modified poly(lactic-co-glycolic acid electrospun fibrous scaffold for bone regeneration

    Directory of Open Access Journals (Sweden)

    Chen SJ

    2015-06-01

    Full Text Available Shijie Chen,1,* Zhiyuan Jian,2,* Linsheng Huang,2,* Wei Xu,3,* Shaohua Liu,4 Dajiang Song,3 Zongmiao Wan,3 Amanda Vaughn,5 Ruisen Zhan,1 Chaoyue Zhang,1 Song Wu,1 Minghua Hu,6 Jinsong Li1 1Department of Orthopaedics, The Third Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 2The First General Surgery Department of Shiyan Taihe Hospital Affiliated to Hubei University of Medicine, Shiyan, People’s Republic of China; 3Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, Shanghai, People’s Republic of China; 4Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 5Department of Molecular Biosciences, Institute of Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX, USA; 6Department of Anthropotomy, Changsha Medical College, Changsha, Hunan, People’s Republic of China *These authors contributed equally to this work Abstract: A mesoporous bioactive glass (MBG surface modified with poly(lactic-co-glycolic acid (PLGA electrospun fibrous scaffold for bone regeneration was prepared by dip-coating a PLGA electrospun fibrous scaffold into MBG precursor solution. Different surface structures and properties were acquired by different coating times. Surface morphology, chemical composition, microstructure, pore size distribution, and hydrophilicity of the PLGA-MBG scaffold were characterized. Results of scanning electron microscopy indicated that MBG surface coating made the scaffold rougher with the increase of MBG content. Scaffolds after MBG modification possessed mesoporous architecture on the surface. The measurements of the water contact angles suggested that the incorporation of MBG into the PLGA scaffold improved the surface hydrophilicity. An energy dispersive spectrometer evidenced that calcium-deficient carbonated hydroxyapatite formed on the PLGA-MBG scaffolds

  10. Novel bioactive materials developed by simulated body fluid evaluation: Surface-modified Ti metal and its alloys.

    Science.gov (United States)

    Kokubo, Tadashi; Yamaguchi, Seiji

    2016-10-15

    Until the discovery of the bone-bonding activity of Bioglass by Hench et al. in the early 1970s, it had not been demonstrated that a synthetic material could bond to living bone without eliciting a foreign body reaction. Since then, various kinds of materials based on calcium phosphate, such as sintered hydroxyapatite and β-tricalcium phosphate have also been shown to bond to living bone. Until the discovery of the bone-bonding activity of Ti metal formed with a sodium titanate surface layer by the present authors in 1996, it had not been shown that a metallic material could bond to living bone. Since then, various kinds of surface-modified Ti metal and its alloys have been found to bond to living bone. Until the discovery of the osteoinduction of porous hydroxyapatite by Yamasaki in 1990, it was unknown whether a synthetic material could induce bone formation even in muscle tissue. Since then, various kinds of porous calcium phosphate ceramics have been shown to induce osteoinduction. Until the discovery of osteoinduction induced by a porous Ti metal formed with a titanium oxide surface layer by Fujibayashi et al. in 2004, it had been unclear whether porous metals would be able to induce osteoinduction. These novel bioactive materials have been developed by systematic research into the apatite formation that occurs on surface-modified Ti metal and its related materials in an acellular simulated body fluid (SBF) having ion concentrations almost equal to those of human blood plasma. Some of the novel bioactive materials based on Ti metal are already in clinical use or clinical trials, such as artificial hip joints and spinal fusion devices. In the present paper, we review how these novel bioactive materials based on Ti metal have been developed based on an evaluation of apatite formation in SBF. Without the SBF evaluation, these novel bioactive materials would most likely never have been developed. On the basis of systematic study of apatite formation on a material

  11. Preparation of Magnetic Sorbent with Surface Modified by C18for Removal of Selected Organic Pollutants from Aqueous Samples

    Science.gov (United States)

    Kuráň, Pavel; Pilnaj, Dominik; Ciencialová, Lucie; Pšenička, Martin

    2017-12-01

    Magnetic sorbents have great potential in environmental applications due to their simple synthesis and separation in magnetic field, usability in heterogeneous systems and low toxicity. Possible syntheses, surface modifications and characteristics were described by Li et al 2013. This type of solid-phase extraction is being successfully used in various fields as health care, microbiology, biotechnologies or sample preconcentration in analytical chemistry. In this preliminary study we report on the preparation and application of magnetically separable sorbent with surface modified by C18 alkyl chain for purification of water contaminated by environmentally hazardous organic compounds. Magnetic cores were co-precipitated from Fe2+ and Fe3+ chlorides in alkalic aqueous solution. Surface of synthetized Fe3O4 was modified with SiO2 by tetraethylorthosilicate to assure physico-chemical stability. Furthermore, Fe3O4/SiO2 complex has been treated by C18 functional group, which provides good affinity towards hydrophobic substances in water. Efficiency of sorption under various conditions has been examined on benzene, toluene, ethylbenzene and xylenes (BTEX), compounds found in petroleum products which contaminate air, soil and groundwater near of store tanks. Sorption kinetics was followed by gas chromatography with mass spectrometry. The preliminary sorption kinetics data and efficiency of BTEX removal point at the possible application of prepared magnetic sorbent for BTEX removal, especially for ethylbenzene and xylenes.

  12. Enhancing performance of P3HT:TiO₂ solar cells using doped and surface modified TiO₂ nanorods.

    Science.gov (United States)

    Tu, Yu-Chieh; Lim, Herman; Chang, Chun-Yu; Shyue, Jing-Jong; Su, Wei-Fang

    2015-06-15

    Here we demonstrated an approach to increase performance of P3HT:TiO2 solar cell either by electron deficient boron or electron rich bismuth doping into TiO2 nanorods. The B doping increases the absorption, crystallinity and electron mobility of TiO2 nanorods. The Bi-doped TiO2 has higher J(sc) as compared with B-doped TiO2, mainly due to the improvement of electron density and increased absorption of TiO2 nanorods. The devices were fabricated from TiO2 nanorods being surface modified by organic dye W-4. The dye facilitates the bandgap alignment and compatibility between TiO2 and P3HT. The power conversion efficiency of solar cell has been increased by 1.33 times and 1.30 times for Bi-doped TiO2 and B-doped TiO2, respectively, as compared with that of as-synthesized TiO2. The results suggest the optical and electronic properties of TiO2 can be tuned by various dopants to enhance the device performance. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Crosslinkable mixed matrix membranes with surface modified molecular sieves for natural gas purification: I. Preparation and experimental results

    KAUST Repository

    Ward, Jason K.

    2011-07-01

    Dense film mixed matrix membranes (MMMs) comprised of SSZ-13 dispersed in a crosslinkable polyimide (PDMC) were fabricated and evaluated for carbon dioxide/methane separations. MMMs containing 25% (w/w) as-received (AR) SSZ-13 exhibited a carbon dioxide permeability of 153 Barrers with a carbon dioxide/methane ideal selectivity of 34.7 at 65. psia and 35 °C. This represents a permeability enhancement of 129% and a decline in selectivity of 4.7% over neat PDMC (PCO2=66.9 Barrers, αCO2/CH4=36.4). A sieve surface modification procedure was developed with the aim of improving SSZ-13/PDMC MMM transport properties. MMMs containing 25% (w/w) surface modified (SM) SSZ-13 exhibited a carbon dioxide permeability of 148 Barrers and carbon dioxide/methane selectivity of 38.9 at 65. psia and 35 °C, representing enhancements in both permeability and selectivity of 121% and 6.9%, respectively. Mixed gas permeation analyses of MMMs containing SM-SSZ-13 using a 10% carbon dioxide/90% methane mixture shows that permeability and selectivity enhancements of 47% and 13%, respectively, over neat PDMC are possible at 700. psia and 35 °C. © 2011 Elsevier B.V.

  14. Crosslinkable mixed matrix membranes with surface modified molecular sieves for natural gas purification: II. Performance characterization under contaminated feed conditions

    KAUST Repository

    Ward, Jason K.

    2011-07-01

    Mixed matrix membranes (MMMs) composed of the crosslinkable polyimide PDMC and surface modified (SM) SSZ-13 have recently been shown to enhance carbon dioxide permeability and carbon dioxide/methane selectivity versus neat PDMC films by as much as 47% and 13%, respectively (Part I). The previous film characterization, however, was performed using ideal, clean mixed gas feeds. In this paper, PDMC/SSZ-13 MMMs are further characterized using more realistic mixed gases containing low concentrations (500 or 1000. ppm) of toluene as a model contaminant. Mixed matrix membranes are shown to outperform pure PDMC films in the presence of toluene with 43% greater carbon dioxide permeability and 12% greater carbon dioxide/selectivity at 35 °C and 700 psia feed pressure. These results suggest that MMMs-in addition to exhibiting enhanced transport properties-may mitigate performance degradation due to antiplasticization effects. Moreover, the analyses presented here show that the reduction in separation performance by trace contaminant-accelerated physical aging can be suppressed greatly with MMMs. © 2011 Elsevier B.V.

  15. Superparamagnetic poly(methyl methacrylate) nanoparticles surface modified with folic acid presenting cell uptake mediated by endocytosis

    Energy Technology Data Exchange (ETDEWEB)

    Feuser, Paulo Emilio [Federal University of Santa Catarina, Department of Chemical Engineering and Food Engineering (Brazil); Jacques, Amanda Virtuoso [Federal University of Santa Catarina, Department of Clinical Analyses (Brazil); Arévalo, Juan Marcelo Carpio; Rocha, Maria Eliane Merlin [Federal University of Paraná, Department of Biochemistry and Molecular Biology (Brazil); Santos-Silva, Maria Claudia dos [Federal University of Santa Catarina, Department of Clinical Analyses (Brazil); Sayer, Claudia; Araújo, Pedro H. Hermes de, E-mail: pedro.h.araujo@ufsc.br [Federal University of Santa Catarina, Department of Chemical Engineering and Food Engineering (Brazil)

    2016-04-15

    The encapsulation of superparamagnetic nanoparticles (MNPs) in polymeric nanoparticles (NPs) with modified surfaces can improve targeted delivery and induce cell death by hyperthermia. The goals of this study were to synthesize and characterize surface modified superparamagnetic poly(methyl methacrylate) with folic acid (FA) prepared by miniemulsion polymerization (MNPsPMMA-FA) and to evaluate their in vitro cytotoxicity and cellular uptake in non-tumor cells, murine fibroblast (L929) cells and tumor cells that overexpressed folate receptor (FR) β, and chronic myeloid leukemia cells in blast crisis (K562). Lastly, hemolysis assays were performed on human red blood cells. MNPsPMMA-FA presented an average mean diameter of 135 nm and a saturation magnetization (Ms) value of 37 emu/g of iron oxide, as well as superparamagnetic behavior. The MNPsPMMA-FA did not present cytotoxicity in L929 and K562 cells. Cellular uptake assays showed a higher uptake of MNPsPMMA-FA than MNPsPMMA in K562 cells when incubated at 37 °C. On the other hand, MNPsPMMA-FA showed a low uptake when endocytosis mechanisms were blocked at low temperature (4 °C), suggesting that the MNPsPMMA-FA uptake was mediated by endocytosis. High concentrations of MNPsPMMA-FA showed hemocompatibility when incubated for 24 h in human red blood cells. Therefore, our results suggest that these carrier systems can be an excellent alternative in targeted drug delivery via FR.

  16. The fabrication of a process heat exchanger for a SO3 decomposer using surface-modified hastelloy X materials

    International Nuclear Information System (INIS)

    Park, Jae Won; Kim, Hyung Jin; Kim Yong Wan

    2008-01-01

    This study investigates the surface modification of a Hastelloy X plate and diffusion bonding in the assembly of surface modified plates. These types of plates are involved in the key processes in the fabrication of a Process Heat Exchanger (PHE) for a SO 3 decomposer. Strong adhesion of a SiC film deposited onto Hastelloy X can be achieved by a thin SiC film deposition and a subsequent N ion beam bombardment followed by an additional deposition of a thicker film that prevents the Hastelloy X surface from becoming exposed to a corrosive environment through the pores. This process not only produces higher corrosion resistance as proved by electrolytic etching but also exhibits higher endurance against thermal stress above 900 .deg. C. A process for a good bonding between Hastelloy X sheets, which is essential for a good heat exchanger, was developed by diffusion bonding. The diffusion bonding was done by mechanically clamping the sheets under a heat treatment at 900 .deg. C. When the clamping jig consisted of materials with a thermal expansion coefficient that was equal to or less than that of the Hastelloy X, sound bonding was achieved

  17. Palladium mixed-metal surface-modified AB5-type intermetallides enhance hydrogen sorption kinetics

    Directory of Open Access Journals (Sweden)

    Roman V. Denys

    2010-09-01

    Full Text Available Surface engineering approaches were adopted in the preparation of advanced hydrogen sorption materials, based on ‘low-temperature’, AB5-type intermetallides. The approaches investigated included micro-encapsulation with palladium and mixed-metal mantles using electroless plating. The influence of micro-encapsulation on the surface morphology and kinetics of hydrogen charging were investigated. It was found that palladium-nickel (Pd-Ni co-deposition by electroless plating significantly improved the kinetics of hydrogen charging of the AB5-type intermetallides at low hydrogen pressure and temperature, after long-term pre-exposure to air. The improvement in the kinetics of hydrogen charging was credited to a synergistic effect between the palladium and nickel atoms in the catalytic mantle and the formation of an ‘interfacial bridge’ for hydrogen diffusion by the nickel atoms in the deposited layer. The developed surface-modified materials may find application in highly selective hydrogen extraction, purification, and storage from impure hydrogen feeds.

  18. Seeking Counterparts to Advanced LIGO/Virgo Transients with Swift

    Science.gov (United States)

    Kanner, Jonah; Camp, Jordan; Racusin, Judith; Gehrels, Neil; White, Darren

    2012-01-01

    Binary neutron star (NS) mergers are among the most promising astrophysical sources of gravitational wave emission for Advanced LIGO and Advanced Virgo, expected to be operational in 2015 . Finding electromagnetic counterparts to these signals will be essential to placing them in an astronomical context. The Swift satellite carries a sensitive X-ray telescope (XRT), and can respond to target-of-opportunity requests within 1-2 hours, and so is uniquely poised to find the X-ray counterparts to LIGO / Virgo triggers. Assuming NS mergers are the progenitors of short gamma-ray bursts (GRBs), some percentage of LIGO/Virgo triggers will be accompanied by X-ray band afterglows that are brighter than 10(exp -12) ergs/s/sq cm in the XRT band one day after the trigger time. We find that a soft X-ray transient of this flux is bright enough to be extremely rare, and so could be confidently associated with even a moderately localized GW signal. We examine two possible search strategies with the Swift XRT to find bright transients in LIGO/Virgo error boxes. In the first strategy, XRT could search a volume of space with a approx.100 Mpc radius by observing approx 30 galaxies over the course of a day, with sufficient depth to observe the expected X-ray afterglow. For an extended LIGO / Virgo horizon distance, the XRT could employ very short 100 s exposures to cover an area of approx 35 square degrees in about a day, and still be sensitive enough to image GW discovered GRB afterglows. These strategies demonstrate that the high X-ray luminosity of short GRBs and the relatively low X-ray transient background combine to make high confidence discoveries of X-ray band counterparts to GW triggers possible, though challenging, with current satellite facilities.

  19. Capability of detecting ultraviolet counterparts of gravitational waves with GLUV

    Science.gov (United States)

    Ridden-Harper, Ryan; Tucker, B. E.; Sharp, R.; Gilbert, J.; Petkovic, M.

    2017-12-01

    With the discovery of gravitational waves (GWs), attention has turned towards detecting counterparts to these sources. In discussions on counterpart signatures and multimessenger follow-up strategies to the GW detections, ultraviolet (UV) signatures have largely been neglected, due to UV facilities being limited to SWIFT, which lacks high-cadence UV survey capabilities. In this paper, we examine the UV signatures from merger models for the major GW sources, highlighting the need for further modelling, while presenting requirements and a design for an effective UV survey telescope. Using the u΄-band models as an analogue, we find that a UV survey telescope requires a limiting magnitude of m_{u^' }}(AB)≈ 24 to fully complement the aLIGO range and sky localization. We show that a network of small, balloon-based UV telescopes with a primary mirror diameter of 30 cm could be capable of covering the aLIGO detection distance from ∼60 to 100 per cent for BNS events and ∼40 per cent for the black hole and a neutron star events. The sensitivity of UV emission to initial conditions suggests that a UV survey telescope would provide a unique data set, which can act as an effective diagnostic to discriminate between models.

  20. Driving protocol for a Floquet topological phase without static counterpart

    Science.gov (United States)

    Quelle, A.; Weitenberg, C.; Sengstock, K.; Morais Smith, C.

    2017-11-01

    Periodically driven systems play a prominent role in optical lattices. In these ultracold atomic systems, driving is used to create a variety of interesting behaviours, of which an important example is provided by topological states of matter. Such Floquet topological phases have a richer classification than their equilibrium counterparts. Although there exist analogues of the equilibrium topological phases that are characterised by a Chern number, the corresponding Hall conductivity, and protected edge states, there is an additional possibility. This is a phase that has a vanishing Chern number and no Hall conductivity, but nevertheless hosts anomalous topological edge states (Rudner et al (2013 Phys. Rev. X 3 031005)). Due to experimental difficulties associated with the observation of such a phase, it has not been experimentally realised in optical lattices so far. In this paper, we show that optical lattices prove to be a good candidate for its realisation and observation, because they can be driven in a controlled manner. Specifically, we present a simple shaking protocol that serves to realise this special Floquet phase, discuss the specific properties that it has, and propose a method to experimentally detect this fascinating topological phase that has no counterpart in equilibrium systems.

  1. Cat Mammary Tumors: Genetic Models for the Human Counterpart

    Directory of Open Access Journals (Sweden)

    Filomena Adega

    2016-08-01

    Full Text Available The records are not clear, but Man has been sheltering the cat inside his home for over 12,000 years. The close proximity of this companion animal, however, goes beyond sharing the same roof; it extends to the great similarity found at the cellular and molecular levels. Researchers have found a striking resemblance between subtypes of feline mammary tumors and their human counterparts that goes from the genes to the pathways involved in cancer initiation and progression. Spontaneous cat mammary pre-invasive intraepithelial lesions (hyperplasias and neoplasias and malignant lesions seem to share a wide repertoire of molecular features with their human counterparts. In the present review, we tried to compile all the genetics aspects published (i.e., chromosomal alterations, critical cancer genes and their expression regarding cat mammary tumors, which support the cat as a valuable alternative in vitro cell and animal model (i.e., cat mammary cell lines and the spontaneous tumors, respectively, but also to present a critical point of view of some of the issues that really need to be investigated in future research.

  2. Hunting Electromagnetic Counterparts of Gravitational-wave Events Using the Zwicky Transient Facility

    Science.gov (United States)

    Ghosh, Shaon; Chatterjee, Deep; Kaplan, David L.; Brady, Patrick R.; Van Sistine, Angela

    2017-11-01

    Detections of coalescing binary black holes by LIGO have opened a new window of transient astronomy. With increasing sensitivity of LIGO and participation of the Virgo detector in Cascina, Italy, we expect to soon detect coalescence of compact binary systems with one or more neutron stars. These are the prime targets for electromagnetic follow-up of gravitational wave triggers, which holds enormous promise of rich science. However, hunting for electromagnetic counterparts of gravitational wave events is a non-trivial task due to the sheer size of the error regions, which could span hundreds of square degrees. This may require deep observation with large field-of-view telescopes and/or use of galaxy catalogs. The Zwicky Transient facility (ZTF), scheduled to begin operation in 2017, is designed to cover such large sky-localization areas. In this work, we present the strategies of efficiently tiling the sky to facilitate the observation of the gravitational wave error regions using ZTF. To do this, we used simulations consisting of 475 binary neutron star coalescences detected using a mix of two- and three-detector networks. Our studies reveal that, using two overlapping sets of ZTF tiles and a (modified) ranked-tiling algorithm, we can cover the gravitational-wave sky-localization regions with half as many pointings as a simple contour-covering algorithm. We then incorporated the ranked-tiling strategy to study our ability to observe the counterparts. This requires optimization of observation depth and localization area coverage. Our results show that observation in r-band with ˜600 seconds of integration time per pointing seems to be optimum for typical assumed brightnesses of electromagnetic counterparts, if we plan to spend equal amount of time per pointing. However, our results also reveal that we can gain by as much as 50% in detection efficiency if we linearly scale our integration time per pointing based on the tile probability.

  3. Investigation of γ-(2,3-Epoxypropoxypropyltrimethoxy Silane Surface Modified Layered Double Hydroxides Improving UV Ageing Resistance of Asphalt

    Directory of Open Access Journals (Sweden)

    Canlin Zhang

    2017-01-01

    Full Text Available γ-(2,3-Epoxypropoxypropyltrimethoxy silane surface modified layered double hydroxides (KH560-LDHs were prepared and used to improve the ultraviolet ageing resistance of asphalt. The results of X-ray photoelectron spectrometry (XPS indicated that KH560 has been successfully grafted onto the surface of LDHs. The agglomeration of LDHs particles notably reduced after KH560 surface modification according to scanning electron microscopy (SEM, which implied that the KH560 surface modification was helpful to promote the dispersibility of LDHs in asphalt. Then, the influence of KH560-LDHs and LDHs on the physical and rheological properties of asphalt before and after UV ageing was thoroughly investigated. The storage stability test showed that the difference in softening point (ΔS of LDHs modified asphalt decreased from 0.6 °C to 0.2 °C at an LDHs content of 1% after KH560 surface modification, and the tendency became more pronounced with the increase of LDH content, indicating that KH560 surface modification could improve the stability of LDHs in asphalt. After UV ageing, the viscous modulus (G’’ of asphalt significantly reduced, and correspondingly, the elastic modulus (G’ and rutting factor (G*/sin δ rapidly increased. Moreover, the asphaltene increased and the amount of “bee-like” structures of the asphalt decreased. Compared with LDHs, KH560-LDHs obviously restrained performance deterioration of the asphalt, and helped to relieve the variation of the chemical compositions and morphology of asphalt, which suggested that the improvement of KH560-LDHs on UV ageing resistance of asphalt was superior to LDHs.

  4. Surface characterization and corrosion behavior of micro-arc oxidized Ti surface modified with hydrothermal treatment and chitosan coating

    International Nuclear Information System (INIS)

    Neupane, Madhav Prasad; Park, Il Song; Lee, Min Ho

    2014-01-01

    In the present work, we describe the surface modification of commercially pure titanium (CP-Ti) by a composite/multilayer coating approach for biomedical applications. CP-Ti samples were treated by micro-arc oxidation (MAO) and subsequently some of the samples were coated with chitosan (Chi) by dip coating method, while others were subjected to hydrothermal treatment (HT) followed by chitosan coating. The MAO, MAO/Chi, and MAO/HT/Chi coated Ti were characterized and their characteristics were compared with CP-Ti. X-ray diffraction and scanning electron microscopy were used to assess the structural and morphological characteristics. The average surface roughness was determined using a surface profilometer. The corrosion resistance of untreated and surface modified Ti in commercial saline at 298 K was evaluated by potentiodynamic polarization test. The results indicated that the chitosan coating is very well integrated with the MAO and MAO/HT coating by physically interlocking itself with the coated layer and almost sealed all the pores. The surface roughness of hydrothermally treated and chitosan coated MAO film was superior evidently to that with other sample groups. The corrosion studies demonstrated that the MAO, hydrothermally treated and chitosan coated sample enhanced the corrosion resistance of titanium. The result indicates that fabrication of hydrothermally treated MAO surface coatings with chitosan is a significant approach to protect the titanium from corrosion, hence enhancing the potential use of titanium as bio-implants. - Highlights: • Micro-arc oxidized (MAO) and hydrothermally treated (HT) Ti surfaces are coated with chitosan (Chi). • The MAO/HT/Chi surface exhibits pores sealing and enhanced the surface roughness. • The MAO/HT/Chi surface significantly increase the corrosion resistance. • The MAO/HT/Chi can be a potential surface of titanium for bio-implants

  5. High-Performance Stretchable Conductive Composite Fibers from Surface-Modified Silver Nanowires and Thermoplastic Polyurethane by Wet Spinning.

    Science.gov (United States)

    Lu, Ying; Jiang, Jianwei; Yoon, Sungho; Kim, Kyung-Shik; Kim, Jae-Hyun; Park, Sanghyuk; Kim, Sang-Ho; Piao, Longhai

    2018-01-17

    Highly stretchable and conductive fibers have attracted great interest as a fundamental building block for the next generation of textile-based electronics. Because of its high conductivity and high aspect ratio, the Ag nanowire (AgNW) has been considered one of the most promising conducting materials for the percolation network-based conductive films and composites. However, the poor dispersibility of AgNWs in hydrophobic polymers has hindered their application to stretchable conductive composite fibers. In this paper, we present a highly stretchable and conductive composite fiber from the co-spinning of surface-modified AgNWs and thermoplastic polyurethane (PU). The surface modification of AgNWs with a polyethylene glycol derivative improved the compatibility of PU and AgNWs, which allowed the NWs to disperse homogeneously in the elastomeric matrix, forming effective percolation networks and causing the composite fiber to show enhanced electrical and mechanical performance. The maximum AgNW mass fraction in the composite fiber was 75.9 wt %, and its initial electrical conductivity was as high as 14 205 S/cm. The composite fibers also exhibited superior stretchability: the maximum rupture strain of the composite fiber with 14.6 wt % AgNW was 786%, and the composite fiber was also conductive even when it was stretched up to 200%. In addition, 2-dimensional (2-D) Ag nanoplates were added to the AgNW/PU composite fibers to increase the stability of the conductive network under repeated stretching and releasing. The Ag nanoplates acted as a bridge to effectively prevent the AgNWs from slippage and greatly improved the stability of the conductive network.

  6. A radio counterpart to a neutron star merger.

    Science.gov (United States)

    Hallinan, G; Corsi, A; Mooley, K P; Hotokezaka, K; Nakar, E; Kasliwal, M M; Kaplan, D L; Frail, D A; Myers, S T; Murphy, T; De, K; Dobie, D; Allison, J R; Bannister, K W; Bhalerao, V; Chandra, P; Clarke, T E; Giacintucci, S; Ho, A Y Q; Horesh, A; Kassim, N E; Kulkarni, S R; Lenc, E; Lockman, F J; Lynch, C; Nichols, D; Nissanke, S; Palliyaguru, N; Peters, W M; Piran, T; Rana, J; Sadler, E M; Singer, L P

    2017-12-22

    Gravitational waves have been detected from a binary neutron star merger event, GW170817. The detection of electromagnetic radiation from the same source has shown that the merger occurred in the outskirts of the galaxy NGC 4993, at a distance of 40 megaparsecs from Earth. We report the detection of a counterpart radio source that appears 16 days after the event, allowing us to diagnose the energetics and environment of the merger. The observed radio emission can be explained by either a collimated ultrarelativistic jet, viewed off-axis, or a cocoon of mildly relativistic ejecta. Within 100 days of the merger, the radio light curves will enable observers to distinguish between these models, and the angular velocity and geometry of the debris will be directly measurable by very long baseline interferometry. Copyright © 2017, American Association for the Advancement of Science.

  7. X-ray Counterparts of Infrared Faint Radio Sources

    Science.gov (United States)

    Schartel, Norbert

    2011-10-01

    Infrared Faint Radio Sources (IFRS) are radio sources with extremely faint or even absent infrared emission in deep Spitzer Surveys. Models of their spectral energy distributions, the ratios of radio to infrared flux densities and their steep radio spectra strongly suggest that IFRS are AGN at high redshifts (2IFRS, but if confirmed, the increased AGN numbers at these redshifts will account for the unresolved part of the X-ray background. The identification of X-ray counterparts of IFRS is considered to be the smoking gun for this hypothesis. We propose to observe 8 IFRS using 30ks pointed observations. X-ray detections of IFRS with different ratios of radio-to-infrared fluxes, will constrain the class-specific SED.

  8. Novel nonlinear optical material with poly(3-hexylthiophene) thin film prepared on quartz glass surface modified by self-assembled monolayer

    Science.gov (United States)

    Ochiai, Shizuyasu; Mototani, Suguru; Ramajothi, Jayaraman; Kojima, Kenzo; Mizutani, Teruyoshi

    2008-08-01

    -order nonlinear optical susceptibility (χ(3)) of RR-P3HT thin films on quartz glass surface modified by ODTS is 1.90 × 10-8 esu. The third-order nonlinear optical susceptibility (χ(3)) of RR-P3HT thin film was found to higher than poly(p-phenylenevinylene) (PPV).

  9. Preparation and characterization of gadolinium-loaded PLGA particles surface modified with RGDS for the detection of thrombus

    Directory of Open Access Journals (Sweden)

    Zhang Y

    2013-10-01

    Full Text Available Yu Zhang,1 Jun Zhou,1 Dajing Guo,1 Meng Ao,2 Yuanyi Zheng,2 Zhigang Wang21Department of Radiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Institute of Ultrasound Imaging, Department of Ultrasound, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaAbstract: Thrombotic disease is a leading cause of death and disability worldwide. The development of magnetic resonance molecular imaging provides potential promise for early disease diagnosis. In this study, we explore the preparation and characterization of gadolinium (Gd-loaded poly (lactic-co-glycolic acid (PLGA particles surface modified with the Arg-Gly-Asp-Ser (RGDS peptide for the detection of thrombus. PLGA was employed as the carrier-delivery system, and a double emulsion solvent-evaporation method (water in oil in water was used to prepare PLGA particles encapsulating the magnetic resonance contrast agent Gd diethylenetriaminepentaacetic acid (DTPA. To synthesize the Gd-PLGA/chitosan (CS-RGDS particles, carbodiimide-mediated amide bond formation was used to graft the RGDS peptide to CS to form a CS-RGDS film that coated the surface of the PLGA particles. Blank PLGA, Gd-PLGA, and Gd-PLGA/CS particles were fabricated using the same water in oil in water method. Our results indicated that the RGDS peptide successfully coated the surface of the Gd-PLGA/CS-RGDS particles. The particles had a regular shape, smooth surface, relatively uniform size, and did not aggregate. The high electron density of the Gd-loaded particles and a translucent film around the particles coated with the CS and CS-RGDS films could be observed by transmission electron microscopy. In vitro experiments demonstrated that the Gd-PLGA/CS-RGDS particles could target thrombi and could be imaged using a clinical magnetic resonance scanner. Compared with the Gd-DTPA solution, the longitudinal relaxation time of

  10. Polycaprolactone Nanocomposites Reinforced with Cellulose Nanocrystals Surface-Modified via Covalent Grafting or Physisorption: A Comparative Study.

    Science.gov (United States)

    Boujemaoui, Assya; Cobo Sanchez, Carmen; Engström, Joakim; Bruce, Carl; Fogelström, Linda; Carlmark, Anna; Malmström, Eva

    2017-10-11

    In the present work, cellulose nanocrystals (CNCs) have been surface-modified either via covalent grafting or through physisorption of poly(n-butyl methacrylate) (PBMA) and employed as reinforcement in PCL. Covalent grafting was achieved by surface-initiated atom transfer radical polymerization (SI-ATRP). Two approaches were utilized for the physisorption: using either micelles of poly(dimethyl aminoethyl methacrylate)-block-poly(n-butyl methacrylate) (PDMAEMA-b-PBMA) or latex nanoparticles of poly(dimethyl aminoethyl methacrylate-co-methacrylic acid)-block-poly(n-butyl methacrylate) (P(DMAEMA-co-MAA)-b-PBMA). Block copolymers (PDMAEMA-b-PBMA)s were obtained by ATRP and subsequently micellized. Latex nanoparticles were produced via reversible addition-fragmentation chain-transfer (RAFT) mediated surfactant-free emulsion polymerization, employing polymer-induced self-assembly (PISA) for the particle formation. For a reliable comparison, the amounts of micelles/latex particles adsorbed and the amount of polymer grafted onto the CNCs were kept similar. Two different chain lengths of PBMA were targeted, below and above the critical molecular weight for chain entanglement of PBMA (M n,c ∼ 56 000 g mol -1 ). Poly(ε-caprolactone) (PCL) nanocomposites reinforced with unmodified and modified CNCs in different weight percentages (0.5, 1, and 3 wt %) were prepared via melt extrusion. The resulting composites were evaluated by UV-vis, scanning electron microscopy (SEM), thermal gravimetric analysis (TGA), and tensile testing. All materials resulted in higher transparency, greater thermal stability, and stronger mechanical properties than unfilled PCL and nanocomposites containing unmodified CNCs. The degradation temperature of PCL reinforced with grafted CNCs was higher than that of micelle-modified CNCs, and the latter was higher than that of latex-adsorbed CNCs with a long PBMA chain length. The results clearly indicate that covalent grafting is superior to

  11. DISCOVERY OF A TRANSIENT GAMMA-RAY COUNTERPART TO FRB 131104

    Energy Technology Data Exchange (ETDEWEB)

    DeLaunay, J. J.; Murase, K.; Mészáros, P.; Keivani, A.; Messick, C.; Mostafá, M. A.; Oikonomou, F.; Tešić, G.; Turley, C. F. [Department of Physics, Pennsylvania State University, University Park, PA 16802 (United States); Fox, D. B., E-mail: jjd330@psu.edu [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States)

    2016-11-20

    We report our discovery in Swift satellite data of a transient gamma-ray counterpart (3.2 σ confidence) to the fast radio burst (FRB) FRB 131104, the first such counterpart to any FRB. The transient has a duration T {sub 90} ≳ 100 s and a fluence S{sub γ} ≈ 4 × 10{sup −6} erg cm{sup −2}, increasing the energy budget for this event by more than a billion times; at the nominal z ≈ 0.55 redshift implied by its dispersion measure, the burst’s gamma-ray energy output is E{sub γ} ≈ 5 × 10{sup 51} erg. The observed radio to gamma-ray fluence ratio for FRB 131104 is consistent with a lower limit we derive from Swift observations of another FRB, which is not detected in gamma-rays, and with an upper limit previously derived for the brightest gamma-ray flare from SGR 1806−20, which was not detected in the radio. X-ray, ultraviolet, and optical observations beginning two days after the FRB do not reveal any associated afterglow, supernova, or transient; Swift observations exclude association with the brightest 65% of Swift gamma-ray burst (GRB) X-ray afterglows, while leaving the possibility of an associated supernova at much more than 10% the FRB’s nominal distance, D ≳ 320 Mpc, largely unconstrained. Transient high-luminosity gamma-ray emission arises most naturally in a relativistic outflow or shock breakout, such as, for example, from magnetar flares, GRBs, relativistic supernovae, and some types of galactic nuclear activity. Our discovery thus bolsters the case for an extragalactic origin for some FRBs and suggests that future rapid-response observations might identify long-lived counterparts, resolving the nature of these mysterious phenomena and realizing their promise as probes of cosmology and fundamental physics.

  12. Energy metabolism in human pluripotent stem cells and their differentiated counterparts.

    Directory of Open Access Journals (Sweden)

    Sandra Varum

    Full Text Available Human pluripotent stem cells have the ability to generate all cell types present in the adult organism, therefore harboring great potential for the in vitro study of differentiation and for the development of cell-based therapies. Nonetheless their use may prove challenging as incomplete differentiation of these cells might lead to tumoregenicity. Interestingly, many cancer types have been reported to display metabolic modifications with features that might be similar to stem cells. Understanding the metabolic properties of human pluripotent stem cells when compared to their differentiated counterparts can thus be of crucial importance. Furthermore recent data has stressed distinct features of different human pluripotent cells lines, namely when comparing embryo-derived human embryonic stem cells (hESCs and induced pluripotent stem cells (IPSCs reprogrammed from somatic cells.We compared the energy metabolism of hESCs, IPSCs, and their somatic counterparts. Focusing on mitochondria, we tracked organelle localization and morphology. Furthermore we performed gene expression analysis of several pathways related to the glucose metabolism, including glycolysis, the pentose phosphate pathway and the tricarboxylic acid (TCA cycle. In addition we determined oxygen consumption rates (OCR using a metabolic extracellular flux analyzer, as well as total intracellular ATP levels by high performance liquid chromatography (HPLC. Finally we explored the expression of key proteins involved in the regulation of glucose metabolism.Our results demonstrate that, although the metabolic signature of IPSCs is not identical to that of hESCs, nonetheless they cluster with hESCs rather than with their somatic counterparts. ATP levels, lactate production and OCR revealed that human pluripotent cells rely mostly on glycolysis to meet their energy demands. Furthermore, our work points to some of the strategies which human pluripotent stem cells may use to maintain high

  13. A dynamic counterpart of Lamb vector in viscous compressible aerodynamics

    International Nuclear Information System (INIS)

    Liu, L Q; Wu, J Z; Shi, Y P; Zhu, J Y

    2014-01-01

    The Lamb vector is known to play a key role in incompressible fluid dynamics and vortex dynamics. In particular, in low-speed steady aerodynamics it is solely responsible for the total force acting on a moving body, known as the vortex force, with the classic two-dimensional (exact) Kutta–Joukowski theorem and three-dimensional (linearized) lifting-line theory as the most famous special applications. In this paper we identify an innovative dynamic counterpart of the Lamb vector in viscous compressible aerodynamics, which we call the compressible Lamb vector. Mathematically, we present a theorem on the dynamic far-field decay law of the vorticity and dilatation fields, and thereby prove that the generalized Lamb vector enjoys exactly the same integral properties as the Lamb vector does in incompressible flow, and hence the vortex-force theory can be generalized to compressible flow with exactly the same general formulation. Moreover, for steady flow of polytropic gas, we show that physically the force exerted on a moving body by the gas consists of a transverse force produced by the original Lamb vector and a new longitudinal force that reflects the effects of compression and irreversible thermodynamics. (paper)

  14. The Hunt for a Counterpart to GW150914

    Science.gov (United States)

    Kohler, Susanna

    2016-07-01

    On 14 September 2015, the Laser Interferometer Gravitational-wave Observatory (LIGO) in a pre-operative testing state at the time detected its first sign of gravitational-waves. The LIGO team sprang into action, performing data-quality checks on this unexpected signal. Within two days, they had sent a notification to 63 observing teams at observatories representing the entire electromagnetic spectrum, from radio to gamma-ray wavelengths.Illustration of a binary neutron star merger. The neutron stars 1) inspiral, 2) can produce a short gamma-ray burst, 3) can fling out hot, radioactive material in the form of a kilonova, and 4) form a massive neutron star or black hole with a possible remnant debris disk around it. [NASA/ESA/A. Feild (STScI)]Thus began the very first hunt for an electromagnetic counterpart to a detected gravitational wave signal.What were they looking for?As two compact objects in a binary system merge, the system is expected to emit energy in the form of gravitational waves. If both of the compact objects are black holes, were unlikely to see any electromagnetic radiation in the process, unless the merger is occurring in an (improbable) environment filled with gas and dust.But if one or both of the two compact objects is a neutron star, then there are a number of electromagnetic signatures that could occur due to energetic outflows. If a relativistic jet forms, we could see a short gamma-ray burst and X-ray, optical, and radio afterglows. Sub-relativistic outflows could produce optical and near-infrared signals, or a radio blast wave.Timeline of observations of GW150914, separated by wavelength band, and relative to the time of the gravitational-wave trigger. The top row shows LIGO information releases. The bottom four rows show high-energy, optical, near-infrared, and radio observations, respectively. Click for a closer look! [Abbott et al. 2016]Surprise SignalSince LIGO and Virgo (LIGOs European counterpart), wereprimarily expecting to detect

  15. ELECTROMAGNETIC COUNTERPARTS TO BLACK HOLE MERGERS DETECTED BY LIGO

    Energy Technology Data Exchange (ETDEWEB)

    Loeb, Abraham, E-mail: aloeb@cfa.harvard.edu [Department of Astronomy, Harvard University, 60 Garden St., Cambridge, MA 02138 (United States)

    2016-03-10

    Mergers of stellar-mass black holes (BHs), such as GW150914 observed by Laser Interferometer Gravitational Wave Observatory (LIGO), are not expected to have electromagnetic counterparts. However, the Fermi GBM detector identified a γ-ray transient 0.4 s after the gravitational wave (GW) signal GW150914 with consistent sky localization. I show that the two signals might be related if the BH binary detected by LIGO originated from two clumps in a dumbbell configuration that formed when the core of a rapidly rotating massive star collapsed. In that case, the BH binary merger was followed by a γ-ray burst (GRB) from a jet that originated in the accretion flow around the remnant BH. A future detection of a GRB afterglow could be used to determine the redshift and precise localization of the source. A population of standard GW sirens with GRB redshifts would provide a new approach for precise measurements of cosmological distances as a function of redshift.

  16. Unidentified EGRET sources and their possible Fermi counterparts

    International Nuclear Information System (INIS)

    Lyapin, A R; Arkhangelskaja, I V; Larin, D S

    2017-01-01

    Unidentified EGRET sources from 3EG catalog have been analyzed. Preliminary data analysis has shown at least 23 of these sources coincide with those in 3FGL Fermi catalogue within 1, 2 and 3 sigma error intervals of the coordinates and fluxes. Their properties are discussed in the presented work. Even 3-sigma difference allows supposing sources similarity because of more than 3-sigma distinctions in values of fluxes between identified EGRET sources and their Fermi counterparts. For instance, the coincidence between 3EG J1255-0549 and 3FGL J1256.1-0547 was reported in Fermi catalogues 1FGL, 2FGL, 3FGL. However, these sources fluxes (in units of 10 −8 photons × cm −2 × s −1 ) in the energy band E > 100 MeV were 179.7 ± 6.7 (3EG), 44.711 ± 0.724 (3FGL), 53.611 ± 0.997 (2FGL) and 67.939 ± 1.861 (1FGL). Such effect was observed for sufficient portion of identified EGRET sources. It could cause by troubles of particles identification by Fermi/LAT trigger system. Very often charged particles recognized as gamma-quanta because of wrong backsplash analysis. Nevertheless, gammas counts as charged particles due analogous reason and rejected during ground data processing. For example, it appears as geomagnetic modulation presence on gamma-quanta count rate latitudinal profiles in energy band E > 20 MeV. (paper)

  17. Thermally conductive tough flexible elastomers as composite of slide-ring materials and surface modified boron nitride particles via plasma in solution

    Science.gov (United States)

    Goto, Taku; Iida, Masaki; Tan, Helen; Liu, Chang; Mayumi, Koichi; Maeda, Rina; Kitahara, Koichi; Hatakeyama, Kazuto; Ito, Tsuyohito; Shimizu, Yoshiki; Yokoyama, Hideaki; Kimura, Kaoru; Ito, Kohzo; Hakuta, Yukiya; Terashima, Kazuo

    2018-03-01

    We have developed a thermally conductive flexible elastomer as a composite material with slide-ring (SR) materials and boron nitride (BN) particles surface-modified via plasma in solution. This composite shows excellent properties as a flexible insulator for thermal management. Surface modification of BN particles using plasma in solution increases the tensile strength, extension ratio at break, toughness, and rubber characteristics of the composites, compared to SR and non-modified BN, while the Young's modulus values are identical. Furthermore, the thermal conductivity also improved as a result of plasma surface modification.

  18. Follow Up of GW170817 and Its Electromagnetic Counterpart by Australian-Led Observing Programmes

    Science.gov (United States)

    Andreoni, I.; Ackley, K.; Cooke, J.; Acharyya, A.; Allison, J. R.; Anderson, G. E.; Ashley, M. C. B.; Baade, D.; Bailes, M.; Bannister, K.; Beardsley, A.; Bessell, M. S.; Bian, F.; Bland, P. A.; Boer, M.; Booler, T.; Brandeker, A.; Brown, I. S.; Buckley, D. A. H.; Chang, S.-W.; Coward, D. M.; Crawford, S.; Crisp, H.; Crosse, B.; Cucchiara, A.; Cupák, M.; de Gois, J. S.; Deller, A.; Devillepoix, H. A. R.; Dobie, D.; Elmer, E.; Emrich, D.; Farah, W.; Farrell, T. J.; Franzen, T.; Gaensler, B. M.; Galloway, D. K.; Gendre, B.; Giblin, T.; Goobar, A.; Green, J.; Hancock, P. J.; Hartig, B. A. D.; Howell, E. J.; Horsley, L.; Hotan, A.; Howie, R. M.; Hu, L.; Hu, Y.; James, C. W.; Johnston, S.; Johnston-Hollitt, M.; Kaplan, D. L.; Kasliwal, M.; Keane, E. F.; Kenney, D.; Klotz, A.; Lau, R.; Laugier, R.; Lenc, E.; Li, X.; Liang, E.; Lidman, C.; Luvaul, L. C.; Lynch, C.; Ma, B.; Macpherson, D.; Mao, J.; McClelland, D. E.; McCully, C.; Möller, A.; Morales, M. F.; Morris, D.; Murphy, T.; Noysena, K.; Onken, C. A.; Orange, N. B.; Osłowski, S.; Pallot, D.; Paxman, J.; Potter, S. B.; Pritchard, T.; Raja, W.; Ridden-Harper, R.; Romero-Colmenero, E.; Sadler, E. M.; Sansom, E. K.; Scalzo, R. A.; Schmidt, B. P.; Scott, S. M.; Seghouani, N.; Shang, Z.; Shannon, R. M.; Shao, L.; Shara, M. M.; Sharp, R.; Sokolowski, M.; Sollerman, J.; Staff, J.; Steele, K.; Sun, T.; Suntzeff, N. B.; Tao, C.; Tingay, S.; Towner, M. C.; Thierry, P.; Trott, C.; Tucker, B. E.; Väisänen, P.; Krishnan, V. Venkatraman; Walker, M.; Wang, L.; Wang, X.; Wayth, R.; Whiting, M.; Williams, A.; Williams, T.; Wolf, C.; Wu, C.; Wu, X.; Yang, J.; Yuan, X.; Zhang, H.; Zhou, J.; Zovaro, H.

    2017-12-01

    The discovery of the first electromagnetic counterpart to a gravitational wave signal has generated follow-up observations by over 50 facilities world-wide, ushering in the new era of multi-messenger astronomy. In this paper, we present follow-up observations of the gravitational wave event GW170817 and its electromagnetic counterpart SSS17a/DLT17ck (IAU label AT2017gfo) by 14 Australian telescopes and partner observatories as part of Australian-based and Australian-led research programs. We report early- to late-time multi-wavelength observations, including optical imaging and spectroscopy, mid-infrared imaging, radio imaging, and searches for fast radio bursts. Our optical spectra reveal that the transient source emission cooled from approximately 6 400 K to 2 100 K over a 7-d period and produced no significant optical emission lines. The spectral profiles, cooling rate, and photometric light curves are consistent with the expected outburst and subsequent processes of a binary neutron star merger. Star formation in the host galaxy probably ceased at least a Gyr ago, although there is evidence for a galaxy merger. Binary pulsars with short (100 Myr) decay times are therefore unlikely progenitors, but pulsars like PSR B1534+12 with its 2.7 Gyr coalescence time could produce such a merger. The displacement ( 2.2 kpc) of the binary star system from the centre of the main galaxy is not unusual for stars in the host galaxy or stars originating in the merging galaxy, and therefore any constraints on the kick velocity imparted to the progenitor are poor.

  19. Africanized honeybees are slower learners than their European counterparts

    Science.gov (United States)

    Couvillon, Margaret J.; Degrandi-Hoffman, Gloria; Gronenberg, Wulfila

    2010-02-01

    Does cognitive ability always correlate with a positive fitness consequence? Previous research in both vertebrates and invertebrates provides mixed results. Here, we compare the learning and memory abilities of Africanized honeybees ( Apis mellifera scutellata hybrid) and European honeybees ( Apis mellifera ligustica). The range of the Africanized honeybee continues to expand, superseding the European honeybee, which led us to hypothesize that they might possess greater cognitive capabilities as revealed by a classical conditioning assay. Surprisingly, we found that fewer Africanized honeybees learn to associate an odor with a reward. Additionally, fewer Africanized honeybees remembered the association a day later. While Africanized honeybees are replacing European honeybees, our results show that they do so despite displaying a relatively poorer performance on an associative learning paradigm.

  20. Explaining electrostatic charging and flow of surface-modified acetaminophen powders as a function of relative humidity through surface energetics.

    Science.gov (United States)

    Jallo, Laila J; Dave, Rajesh N

    2015-07-01

    Powder flow involves particle-particle and particle-vessel contacts and separation resulting in electrostatic charging. This important phenomenon was studied for uncoated and dry-coated micronized acetaminophen (MAPAP) as a function of relative humidity. The main hypothesis is that by modifying powder surface energy via dry coating of MAPAP performed using magnetically assisted impaction coating, its charging tendency, flow can be controlled. The examination of the relationship between electrostatic charging, powder flow, and the surface energies of the powders revealed that an improvement in flow because of dry coating corresponded to a decrease in the charging of the particles. A general trend of reduction in both electrostatic charging and dispersive surface energy with dry coating and relative humidity were also observed, except that a divergent behavior was observed at higher relative humidities (≥55% RH). The uncoated powder was found to have strong electron acceptor characteristic as compared with the dry coated. The adhesion energy between the particles and the tubes used for the electrostatic charging qualitatively predicted the decreasing trend in electrostatic charging from plastic tubes to stainless steel. In summary, the surface energies of the powders and the vessel could explain the electrostatic charging behavior and charge reduction because of dry coating. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  1. Investigation of simultaneously existed Raman scattering enhancement and inhibiting fluorescence using surface modified gold nanostars as SERS probes.

    Science.gov (United States)

    Shan, Feng; Zhang, Xiao-Yang; Fu, Xing-Chang; Zhang, Li-Jiang; Su, Dan; Wang, Shan-Jiang; Wu, Jing-Yuan; Zhang, Tong

    2017-07-28

    One of the main challenges for highly sensitive surface-enhanced Raman scattering (SERS) detection is the noise interference of fluorescence signals arising from the analyte molecules. Here we used three types of gold nanostars (GNSs) SERS probes treated by different surface modification methods to reveal the simultaneously existed Raman scattering enhancement and inhibiting fluorescence behaviors during the SERS detection process. As the distance between the metal nanostructures and the analyte molecules can be well controlled by these three surface modification methods, we demonstrated that the fluorescence signals can be either quenched or enhanced during the detection. We found that fluorescence quenching will occur when analyte molecules are closely contacted to the surface of GNSs, leading to a ~100 fold enhancement of the SERS sensitivity. An optimized Raman signal detection limit, as low as the level of 10 -11  M, were achieved when Rhodamine 6 G were used as the analyte. The presented fluorescence-free GNSs SERS substrates with plentiful hot spots and controllable surface plasmon resonance wavelengths, fabricated using a cost-effective self-assembling method, can be very competitive candidates for high-sensitive SERS applications.

  2. Revisiting bone targeting potential of novel hydroxyapatite based surface modified PLGA nanoparticles of risedronate: Pharmacokinetic and biochemical assessment.

    Science.gov (United States)

    Rawat, Purnima; Ahmad, Iqbal; Thomas, Shindu C; Pandey, Shweta; Vohora, Divya; Gupta, Sarika; Ahmad, Farhan Jalees; Talegaonkar, Sushama

    2016-06-15

    Hydroxyapatite based biodegradable mPEG-PLGA nanoparticles of risedronate (mPEG-PLGA-RIS-HA) were prepared by water miscible dialysis method for synergistic treatment of osteoporosis. The bone targeting potential of prepared nanoparticles was evaluated by performing the cell viability study and protein estimation in pre-osteoblast cell line (MC3T3E1). Biochemical and in-vivo pharmacokinetic studies on osteoporotic rat model treated with different formulations were performed. Under the biochemical study ALP, TRAP, HxP and Calcium levels were determined. Osteoporotic model treated with prepared nanoparticles indicated significant effect on bone. Pharmacokinetic studies revealed 6-fold and 4-fold increase in the relative bioavailability after intravenous and oral administration of nanoparticles respectively as compared to marketed formulation confirming better effective drug transport. Biochemical investigations also showed a significant change in biomarker level which ultimately lead to bone formation/resorption. A stability analysis has also been carried out according to ICH guidelines (Q1AR2) and shelf life was found to be 1year and 4 months for the prepared formulation. Thus the results of present studies indicated that mPEG-PLGA-RIS-HA NPs has a great potential for sustained delivery of RIS for the treatment and prevention of osteoporosis and to minimize the adverse effects of RIS typically induced by its oral administration. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Utilization of Polyaniline (PAni) as Conductive Filler on Poly (Ethylene Oxide) / Poly (Vinyl Chloride) Films: Effects of Naphthalene as Surface Modifier on Electrical Conductivity

    Science.gov (United States)

    Yazid, Mohammed Izzuddeen Bin Mohd; Ghani, Supri A.; Jin, Tan Soo; Fazlina Osman, Azlin; Din, Siti Hajar Mohd

    2017-10-01

    The aim of the study was to utilize polyaniline (PAni) as conductive filler in poly (ethylene oxide) / poly (vinyl chloride) (PEO/PVC) films. Naphthalene was used as surface modifier to increase the properties of PEO/PVC/PAni films. The electrical conductivity of PEO/PVC/PAni film improved with higher loading of PAni until it reached the percolation threshold at 10 wt%. Moreover, the conductivity of the films also improved with the addition of naphthalene compared to the films without naphthalene. These enhancements were due to the improved interfacial bonding between PEO/PVC blend and PAni, which were supported by scanning electron microscopy (SEM) analysis. In addition, no new chemical bonding was created with the incorporation of naphthalene as proved by the FTIR analysis.

  4. Effect of type and loading of surface-modifying agent on mechanical properties of modified geothermal scale powder/stereolithography polymer composite

    Science.gov (United States)

    Tilendo, A. C.; Pajarito, B. B.

    2017-05-01

    This study investigated the effect of stearic acid (SA), glycerol monostearate (GMS) and 3-trimethoxysilylpropyl methacrylate (TSPM) at varied loadings on the hardness and flexural properties of modified geothermal scale powder (GSP)/stereolithography (SLA) polymer composite. TSPM-modified GSP/SLA composite has the highest value of hardness due to increased filler dispersion and crystallinity. Hardness of GSP/SLA composite increases with loading of surface-modifying agent due to increase filler dispersion. Pronounced effect of surface modification to flexural modulus is observed. While low loading of SA and GMS leads to reduction of flexural modulus, increasing loading enhances the said property. Further increase of SA deteriorates the property. TSPM-modified GSP enhances the modulus due to increased crystalline phase of the system owing to TSPM copolymerization. Likewise, addition of SA and GMS increases flexural strength due to efficient reduction of filler agglomerates. However, unreacted TSPM produces weak interfaces and poor adhesion between GSP and SLA matrix.

  5. Comparative evaluation of corrosion behaviour of type K thin film thermocouple and its bulk counterpart

    International Nuclear Information System (INIS)

    Mukherjee, S.K.; Barhai, P.K.; Srikanth, S.

    2011-01-01

    Highlights: → Anodic vacuum arc deposited chromel and alumel films are more 'noble' in 5% NaCl solution than their respective wires. → Chromel undergoes localised corrosion while alumel shows uniform corrosion. → Virgin samples of chromel-alumel TFTCs exhibit good thermoelectric response. → Their thermoelectric outputs remain largely unaffected when shelved under normal atmospheric conditions. → After 288 h of exposure in salt spray environment, their thermoelectric outputs show noticeable change due to size effects. - Abstract: This paper investigates the corrosion behaviour of type K thermoelements and their thin films, and compares the performance of chromel-alumel thin film thermocouple with its wire counterpart before and after exposure to 5% NaCl medium. Potentiodynamic polarisation tests reveal that chromel and alumel films are more 'noble' than their respective wires. Alumel corrodes faster when coupled with chromel in films than as wires. Secondary electron micrographs and electrochemical impedance spectroscopy measurements suggest that chromel shows localised corrosion while alumel undergoes uniform corrosion. Corrosion adversely affects the thermocouple output and introduces an uncertainty in the measurement.

  6. Optimization of CO2 adsorption capacity and cyclical adsorption/desorption on tetraethylenepentamine-supported surface-modified hydrotalcite.

    Science.gov (United States)

    Thouchprasitchai, Nutthavich; Pintuyothin, Nuthapol; Pongstabodee, Sangobtip

    2018-03-01

    The objective of this research was to investigate CO 2 adsorption capacity of tetraethylenepentamine-functionalized basic-modified calcined hydrotalcite (TEPA/b-cHT) sorbents at atmospheric pressure formed under varying TEPA loading levels, temperatures, sorbent weight to total gaseous flow rate (W/F) ratios and CO 2 concentrations in the influent gas. The TEPA/b-cHT sorbents were characterized by means of X-ray diffraction (XRD), Fourier transform infrared spectrometry (FT-IR), thermal gravimetric analysis (TGA), Brunauer-Emmet-Teller (BET) analysis of nitrogen (N 2 ) adsorption/desorption and carbon-hydrogen-nitrogen (CHN) elemental analysis. Moreover, a full 2 4 factorial design with three central points at a 95% confidence interval was used to screen important factor(s) on the CO 2 adsorption capacity. It revealed that 85.0% variation in the capacity came from the influence of four main factors and the 15.0% one was from their interactions. A face-centered central composite design response surface method (FCCCD-RSM) was then employed to optimize the condition, the maximal capacity of 5.5-6.1mmol/g was achieved when operating with a TEPA loading level of 39%-49% (W/W), temperature of 76-90°C, W/F ratio of 1.7-2.60(g·sec)/cm 3 and CO 2 concentration of 27%-41% (V/V). The model fitted sufficiently the experimental data with an error range of ±1.5%. From cyclical adsorption/desorption and selectivity at the optimal condition, the 40%TEPA/b-cHT still expressed its effective performance after eight cycles. Copyright © 2017. Published by Elsevier B.V.

  7. Characterization, antioxidant and cytotoxicity evaluation of green synthesized silver nanoparticles using Cleistanthus collinus extract as surface modifier

    Energy Technology Data Exchange (ETDEWEB)

    Kanipandian, Nagarajan [Laboratory of Aquabiotics/Nanoscience, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu (India); Kannan, Soundarapandian [Proteomics and Molecular Cell Physiology Laboratory, Department of Zoology, Periyar University, Salem 636 011, Tamil Nadu (India); Ramesh, Ramar; Subramanian, Periyasamy [Laboratory of Aquabiotics/Nanoscience, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu (India); Thirumurugan, Ramasamy, E-mail: ramthiru72@gmail.com [Laboratory of Aquabiotics/Nanoscience, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu (India)

    2014-01-01

    Graphical abstract: The figure is the TEM image of green synthesized silver nanoparticles from Cleistanthus collinus. In this investigation we have used the poisonous plant as a reducing and capping agent. This is a first time data to synthesis the metal nanoparticles using poisonous plant. - Highlights: • A hitherto unreported venomous plant mediated AgNPs synthesis. • The particle size is observed in the range of 20–40 nm. • Surface morphology of the well-dispersed silver nanoparticles is studied using SEM and TEM. • Crystalline nature of AgNPs is confirmed by X-ray diffraction analysis. • Antioxidant activities of green synthesized AgNPs are tested in vitro. - Abstract: We report, here a simple green method for the preparation of silver nanoparticles (AgNPs) using the plant extract of Cleistanthus collinus as potential phyto reducer. The synthesized AgNPs were characterized by UV–vis spectra, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The obtained results confirmed that the AgNPs were crystalline in nature and the morphological studies reveal the spherical shape of AgNPs with size ranging from 20 to 40 nm. The in vitro antioxidant activity of AgNPs showed a significant effect on scavenging of free radicals. The cytotoxicity study exhibited a dose-dependent effect against human lung cancer cells (A549) and normal cells (HBL-100), the inhibitory concentration (IC{sub 50}) were found to be 30 μg/mL and 60 μg/mL respectively. The in vivo histopathology of mouse organs proved that AgNPs does not possess toxic effect and can be extensively applied in biomedical sciences.

  8. Comparison of Guided Bone Regeneration Between Surface-Modified and Pristine Titanium Membranes in a Rat Calvarial Model.

    Science.gov (United States)

    Nguyen, Thuy-Duong; Moon, So-Hee; Oh, Tae-Ju; Seok, Jung-Jin; Lee, Min-Ho; Bae, Tae-Sung

    2016-01-01

    The objectives of this study were to evaluate bioactivity of a titanium membrane with anodization, cyclic precalcification, and heat (APH) treatment (APHTM), and to compare APHTM and nontreated titanium membrane (NTTM) in guided bone regeneration using histologic analysis and microcomputed tomography (micro-CT). APHTM samples were prepared and immersed in simulated body fluid for 2 days, then observed using field-emission scanning electron microscopy, followed by an analysis of calcium and phosphate precipitation using an energy dispersive x-ray spectroscopy. For the in vivo experiment, critical-size defects were created in rat calvaria (diameter, 8 mm) and treated with either APHTM or NTTM (n = 14 each). Biopsies were performed at 2 and 4 weeks for histologic analysis (n = 3 per group each time). Fluorochrome bone markers were injected in three rats in each group at 3 (alizarin red) and 5 weeks (calcein green), followed by histologic examination at 7 weeks. Micro-CT was performed at 8 weeks (n = 5 per group). APHTM exhibited high bioactivity, characterized by dense nano-sized flakelike crystals throughout the membrane and an increase in the calcium-phosphate concentrations after 2-day immersion in simulated body fluid. At 2 and 4 weeks, APHTM samples showed an intimate bone formation onto the membrane, whereas NTTM samples demonstrated interposition of connective tissue between the membrane and newly formed bone. The same pattern was found in the fluorescent study. The micro-CT analysis revealed significantly lower bone volume but higher bone mineral density in the APHTM samples than in the NTTM samples (P bone formation toward the membrane, thus increasing structural durability for bone regeneration. Further research is warranted to confirm the results found in these in vitro and in vivo experiments.

  9. VizieR Online Data Catalog: Selecting IRAC counterparts to SMGs (Alberts+, 2013)

    Science.gov (United States)

    Alberts, S.; Wilson, G. W.; Lu, Y.; Johnson, S.; Yun, M. S.; Scott, K. S.; Pope, A.; Aretxaga, I.; Ezawa, H.; Hughes, D. H.; Kawabe, R.; Kim, S.; Kohno, K.; Oshima, T.

    2014-05-01

    We present a new submm/mm galaxy counterpart identification technique which builds on the use of Spitzer Infrared Array Camera (IRAC) colours as discriminators between likely counterparts and the general IRAC galaxy population. Using 102 radio- and Submillimeter Array-confirmed counterparts to AzTEC sources across three fields [Great Observatories Origins Deep Survey-North, -South and Cosmic Evolution Survey (COSMOS)], we develop a non-parametric IRAC colour-colour characteristic density distribution, which, when combined with positional uncertainty information via likelihood ratios, allows us to rank all potential IRAC counterparts around submillimetre galaxies (SMGs) and calculate the significance of each ranking via the reliability factor. We report all robust and tentative radio counterparts to SMGs, the first such list available for AzTEC/COSMOS, as well as the highest ranked IRAC counterparts for all AzTEC SMGs in these fields as determined by our technique. We demonstrate that the technique is free of radio bias and thus applicable regardless of radio detections. For observations made with a moderate beam size (~18"), this technique identifies ~85% of SMG counterparts. For much larger beam sizes (>~30"), we report identification rates of 33-49%. Using simulations, we demonstrate that this technique is an improvement over using positional information alone for observations with facilities such as AzTEC on the Large Millimeter Telescope and Submillimeter Common User Bolometer Array 2 on the James Clerk Maxwell Telescope. (3 data files).

  10. Independent introductions and admixtures have contributed to adaptation of European maize and its American counterparts.

    Directory of Open Access Journals (Sweden)

    Jean-Tristan Brandenburg

    2017-03-01

    Full Text Available Through the local selection of landraces, humans have guided the adaptation of crops to a vast range of climatic and ecological conditions. This is particularly true of maize, which was domesticated in a restricted area of Mexico but now displays one of the broadest cultivated ranges worldwide. Here, we sequenced 67 genomes with an average sequencing depth of 18x to document routes of introduction, admixture and selective history of European maize and its American counterparts. To avoid the confounding effects of recent breeding, we targeted germplasm (lines directly derived from landraces. Among our lines, we discovered 22,294,769 SNPs and between 0.9% to 4.1% residual heterozygosity. Using a segmentation method, we identified 6,978 segments of unexpectedly high rate of heterozygosity. These segments point to genes potentially involved in inbreeding depression, and to a lesser extent to the presence of structural variants. Genetic structuring and inferences of historical splits revealed 5 genetic groups and two independent European introductions, with modest bottleneck signatures. Our results further revealed admixtures between distinct sources that have contributed to the establishment of 3 groups at intermediate latitudes in North America and Europe. We combined differentiation- and diversity-based statistics to identify both genes and gene networks displaying strong signals of selection. These include genes/gene networks involved in flowering time, drought and cold tolerance, plant defense and starch properties. Overall, our results provide novel insights into the evolutionary history of European maize and highlight a major role of admixture in environmental adaptation, paralleling recent findings in humans.

  11. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. I. Discovery of the Optical Counterpart Using the Dark Energy Camera

    Science.gov (United States)

    Soares-Santos, M.; Holz, D. E.; Annis, J.; Chornock, R.; Herner, K.; Berger, E.; Brout, D.; Chen, H.-Y.; Kessler, R.; Sako, M.; Allam, S.; Tucker, D. L.; Butler, R. E.; Palmese, A.; Doctor, Z.; Diehl, H. T.; Frieman, J.; Yanny, B.; Lin, H.; Scolnic, D.; Cowperthwaite, P.; Neilsen, E.; Marriner, J.; Kuropatkin, N.; Hartley, W. G.; Paz-Chinchón, F.; Alexander, K. D.; Balbinot, E.; Blanchard, P.; Brown, D. A.; Carlin, J. L.; Conselice, C.; Cook, E. R.; Drlica-Wagner, A.; Drout, M. R.; Durret, F.; Eftekhari, T.; Farr, B.; Finley, D. A.; Foley, R. J.; Fong, W.; Fryer, C. L.; García-Bellido, J.; Gill, M. S. S.; Gruendl, R. A.; Hanna, C.; Kasen, D.; Li, T. S.; Lopes, P. A. A.; Lourenço, A. C. C.; Margutti, R.; Marshall, J. L.; Matheson, T.; Medina, G. E.; Metzger, B. D.; Muñoz, R. R.; Muir, J.; Nicholl, M.; Quataert, E.; Rest, A.; Sauseda, M.; Schlegel, D. J.; Secco, L. F.; Sobreira, F.; Stebbins, A.; Villar, V. A.; Vivas, K.; Walker, A. R.; Wester, W.; Williams, P. K. G.; Zenteno, A.; Zhang, Y.; Abbott, T. M. C.; Abdalla, F. B.; Banerji, M.; Bechtol, K.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Castander, F. J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; Davis, C.; Desai, S.; Dietrich, J. P.; Doel, P.; Eifler, T. F.; Fernandez, E.; Flaugher, B.; Fosalba, P.; Gaztanaga, E.; Gerdes, D. W.; Giannantonio, T.; Goldstein, D. A.; Gruen, D.; Gschwend, J.; Gutierrez, G.; Honscheid, K.; Jain, B.; James, D. J.; Jeltema, T.; Johnson, M. W. G.; Johnson, M. D.; Kent, S.; Krause, E.; Kron, R.; Kuehn, K.; Kuhlmann, S.; Lahav, O.; Lima, M.; Maia, M. A. G.; March, M.; McMahon, R. G.; Menanteau, F.; Miquel, R.; Mohr, J. J.; Nichol, R. C.; Nord, B.; Ogando, R. L. C.; Petravick, D.; Plazas, A. A.; Romer, A. K.; Roodman, A.; Rykoff, E. S.; Sanchez, E.; Scarpine, V.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, M.; Smith, R. C.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Thomas, R. C.; Troxel, M. A.; Vikram, V.; Wechsler, R. H.; Weller, J.; Dark Energy Survey; Dark Energy Camera GW-EM Collaboration

    2017-10-01

    We present the Dark Energy Camera (DECam) discovery of the optical counterpart of the first binary neutron star merger detected through gravitational-wave emission, GW170817. Our observations commenced 10.5 hr post-merger, as soon as the localization region became accessible from Chile. We imaged 70 deg2 in the I and z bands, covering 93% of the initial integrated localization probability, to a depth necessary to identify likely optical counterparts (e.g., a kilonova). At 11.4 hr post-merger we detected a bright optical transient located 10\\buildrel{\\prime\\prime}\\over{.} 6 from the nucleus of NGC 4993 at redshift z = 0.0098, consistent (for {H}0=70 km s-1 Mpc-1) with the distance of 40 ± 8 Mpc reported by the LIGO Scientific Collaboration and the Virgo Collaboration (LVC). At detection the transient had magnitudes of I=17.3 and z=17.4, and thus an absolute magnitude of {M}I=-15.7, in the luminosity range expected for a kilonova. We identified 1500 potential transient candidates. Applying simple selection criteria aimed at rejecting background events such as supernovae, we find the transient associated with NGC 4993 as the only remaining plausible counterpart, and reject chance coincidence at the 99.5% confidence level. We therefore conclude that the optical counterpart we have identified near NGC 4993 is associated with GW170817. This discovery ushers in the era of multi-messenger astronomy with gravitational waves and demonstrates the power of DECam to identify the optical counterparts of gravitational-wave sources.

  12. Search for Electromagnetic Counterparts to LIGO-Virgo Candidates: Expanded Very Large Array Observations

    Science.gov (United States)

    Lazio, Joseph; Keating, Katie; Jenet, F. A.; Kassim, N. E.

    2011-01-01

    This paper summarizes a search for radio wavelength counterparts to candidate gravitational wave events. The identification of an electromagnetic counterpart could provide a more complete understanding of a gravitational wave event, including such characteristics as the location and the nature of the progenitor. We used the Expanded Very Large Array (EVLA) to search six galaxies which were identified as potential hosts for two candidate gravitational wave events. We summarize our procedures and discuss preliminary results.

  13. An Instructor’s Guide for the Building and Sustaining Foreign Counterpart Organizations Curriculum

    Science.gov (United States)

    2016-02-01

    Collectivist values and perspectives may differ from ours, thus advisors should take time to understand the viewpoint( s) of counterparts. • A counterpart-led...2003). Levels of organizational trust in individualist versus collectivist societies: A seven-nation study. Organizational Science, 14, 81-90. Keller...strategies that work in collectivist cultures where U.S. military advisors and other senior U.S. government leaders are likely to be assigned. Based on the

  14. Surface Modifier-Free Organic-Inorganic Hybridization to Produce Optically Transparent and Highly Refractive Bulk Materials Composed of Epoxy Resins and ZrO2 Nanoparticles.

    Science.gov (United States)

    Enomoto, Kazushi; Kikuchi, Moriya; Narumi, Atsushi; Kawaguchi, Seigou

    2018-04-02

    Surface modifier-free hybridization of ZrO 2 nanoparticles (NPs) with epoxy-based polymers is demonstrated for the first time to afford highly transparent and refractive bulk materials. This is achieved by a unique and versatile hybridization via the one-pot direct phase transfer of ZrO 2 NPs from water to epoxy monomers without any aggregation followed by curing with anhydride. Three types of representative epoxy monomers, bisphenol A glycidyl ether (BADGE), 3,4-epoxycyclohexylmethyl-3',4'-epoxycyclohexane carboxylate (CEL), and 1,3,5-tris(3-(oxiran-2-yl)propyl)-1,3,5-triazinane-2,4,6-trione (TEPIC) are used to produce transparent viscous dispersions. The resulting ZrO 2 NPs are thoroughly characterized using dynamic light scattering (DLS), transmission electron microscopy (TEM), FT-IR, and solid state 13 C CP/MAS NMR measurements. The results from DLS and TEM analyses indicate nanodispersion of ZrO 2 into epoxy monomers as a continuous medium. A surface modification mechanism and the binding fashion during phase transfer are proposed based on the FT-IR and solid state 13 C CP/MAS NMR measurements. Epoxy-based hybrid materials with a high transparency and refractive index are successfully fabricated by heat curing or polymerizing a mixture of monomers containing epoxy-functionalized ZrO 2 NPs and methylhexahydrophthalic anhydride (MHHPA) in the presence of a phosphoric catalyst (PX). The TEM and small-angle X-ray scattering measurements of the hybrids show a nanodispersion of ZrO 2 in the epoxy networks. The refractive index at 594 nm ( n 594 ) increases up to 1.765 for BADGE-based hybrids, 1.667 for CEL-based hybrids, and 1.693 for TEPIC-based hybrids. Their refractive indices and Abbe's numbers are quantitatively described by the Lorentz-Lorenz effective medium expansion theory. Their transmissivity is also reasonably explained using Fresnel refraction, Rayleigh scattering, and the Lambert-Beer theories. This surface modifier-free hybridization provides a

  15. Green Preparation of Epoxy/Graphene Oxide Nanocomposites Using a Glycidylamine Epoxy Resin as the Surface Modifier and Phase Transfer Agent of Graphene Oxide.

    Science.gov (United States)

    Tang, Xinlei; Zhou, Yang; Peng, Mao

    2016-01-27

    In studies of epoxy/graphene oxide (GO) nanocomposites, organic solvents are commonly used to disperse GO, and vigorous mechanical processes and complicated modification of GO are usually required, increasing the cost and hindering the development and application of epoxy nanocomposites. Here, we report a green, facile, and efficient method of preparing epoxy/GO nanocomposites. When triglycidyl para-aminophenol (TGPAP), a commercially available glycidyl amine epoxy resin with one tertiary amine group per molecule, is used as both the surface modifier and phase transfer agent of GO, GO can be directly and rapidly transferred from water to diglycidyl ether of bisphenol A and other types of epoxy resins by manual stirring under ambient conditions, whereas GO cannot be transferred to these epoxy resins in the absence of TGPAP. The interaction between TGPAP and GO and the effect of the TGPAP content on the dispersion of GO in the epoxy matrix were investigated systematically. Superior dispersion and exfoliation of GO nanosheets and remarkably improved mechanical properties, including tensile and flexural properties, toughness, storage modulus, and microhardness, of the epoxy/GO nanocomposites with a suitable amount of TGPAP were demonstrated. This method is organic-solvent-free and technically feasible for large-scale preparation of high-performance nanocomposites; it opens up new opportunities for exploiting the unique properties of graphene or even other nanofillers for a wide range of applications.

  16. A novel tri-layer flexible piezoelectric nanogenerator based on surface- modified graphene and PVDF-BaTiO3 nanocomposites

    Science.gov (United States)

    Yaqoob, Usman; Uddin, A. S. M. Iftekhar; Chung, Gwiy-Sang

    2017-05-01

    The fabrication and characterization of a novel tri-layer piezoelectric nanogenerator (PNG) based on poly(vinylidene fluoride) (PVDF), barium titanate (BTO), and surface-modified n- type graphene (n-Gr) have been investigated. The n-Gr, with its majority of negative charge carriers, plays a vital role in enhancing the energy-harvesting performance by aligning the dipoles in one direction. The tri-layer structure obtains by stacking two layers of PVDF-BTO nanocomposite films, one on each side of the n-Gr layer. The fabricated tri-layer PNG shows a maximum output voltage of 10 V (pk-pk) along with a current of 2.5 μA (pk-pk) at an applied force of 2 N. Furthermore, the PNG Exhibits 5.8 μW instantaneous power at 1 MΩ load resistance. Moreover, the fabricated device demonstrated good stability even after 1000 pressing-releasing cycles. This novel tri-layer PNG structure can opens a promising avenue for future piezoelectric generating technologies.

  17. Tribological evaluation of surface modified H13 tool steel in warm forming of Ti–6Al–4V titanium alloy sheet

    Directory of Open Access Journals (Sweden)

    Wang Dan

    2014-08-01

    Full Text Available The H13 hot-working tool steel is widely used as die material in the warm forming of Ti–6Al–4V titanium alloy sheet. However, under the heating condition, severe friction and lubricating conditions between the H13 tools and Ti–6Al–4V titanium alloy sheet would cause difficulty in guaranteeing forming quality. Surface modification may be used to control the level of friction force, reduce the friction wear and extend the service life of dies. In this paper, four surface modification methods (chromium plating, TiAlN coating, surface polishing and nitriding treatment were applied to the H13 surfaces. Taking the coefficient of friction (CoF and the wear degree as evaluation indicators, the high-temperature tribological behavior of the surface modified H13 steel was experimentally investigated under different tribological conditions. The results of this study indicate that the tribological properties of the TiAlN coating under dry friction condition are better than the others for a wide range of temperature (from room temperature to 500 °C, while there is little difference of tribological properties between different surface modifications under graphite lubricated condition, and the variation law of CoF with temperature under graphite lubricated is opposite to that under the dry friction.

  18. Fatigue behavior of Ti–6Al–4V alloy in saline solution with the surface modified at a micro- and nanoscale by chemical treatment

    International Nuclear Information System (INIS)

    Claros, Cesar Adolfo Escobar; Oliveira, Diego Pedreira; Campanelli, Leonardo Contri; Pereira da Silva, Paulo Sergio Carvalho; Bolfarini, Claudemiro

    2016-01-01

    This work evaluated the influence of the surface modification using acid etching combined with alkaline treatment on the fatigue strength of Ti–6Al–4V ELI alloy. The topography developed by chemical surface treatments (CST) was examined by scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). Increased roughness and effective surface area were investigated and compared with the Ti–6Al–4V samples without modification. Surface composition was analyzed by energy dispersive X-ray spectroscopy (EDS). Axial fatigue resistance of polished and modified surfaces was determined by stepwise load increase tests and staircase test method. Light microscopy and SEM were employed to examine the fracture surface of the tested specimens. According to the results, a similar fatigue behavior was found and a negligible difference in the fatigue crack nucleation was observed for the Ti–6Al–4V with CST in comparison to the samples without treatment. - Highlights: • Fatigue behavior of Ti–6Al–4V with the surface modified by chemical treatments • The topography developed did not induce differences in the fatigue resistance. • Untreated and chemically treated surfaces presented fractographic similarities.

  19. Antibacterial activity and biofilm inhibition by surface modified titanium alloy medical implants following application of silver, titanium dioxide and hydroxyapatite nanocoatings.

    Science.gov (United States)

    Besinis, A; Hadi, S D; Le, H R; Tredwin, C; Handy, R D

    2017-04-01

    One of the most common causes of implant failure is peri-implantitis, which is caused by bacterial biofilm formation on the surfaces of dental implants. Modification of the surface nanotopography has been suggested to affect bacterial adherence to implants. Silver nanoparticles are also known for their antibacterial properties. In this study, titanium alloy implants were surface modified following silver plating, anodisation and sintering techniques to create a combination of silver, titanium dioxide and hydroxyapatite (HA) nanocoatings. Their antibacterial performance was quantitatively assessed by measuring the growth of Streptococcus sanguinis, proportion of live/dead cells and lactate production by the microbes over 24 h. Application of a dual layered silver-HA nanocoating to the surface of implants successfully inhibited bacterial growth in the surrounding media (100% mortality), whereas the formation of bacterial biofilm on the implant surfaces was reduced by 97.5%. Uncoated controls and titanium dioxide nanocoatings showed no antibacterial effect. Both silver and HA nanocoatings were found to be very stable in biological fluids with material loss, as a result of dissolution, to be less than 0.07% for the silver nanocoatings after 24 h in a modified Krebs-Ringer bicarbonate buffer. No dissolution was detected for the HA nanocoatings. Thus, application of a dual layered silver-HA nanocoating to titanium alloy implants creates a surface with antibiofilm properties without compromising the HA biocompatibility required for successful osseointegration and accelerated bone healing.

  20. Surface-modified carbon nanotube coating on high-voltage LiNi0.5Mn1.5O4 cathodes for lithium ion batteries

    Science.gov (United States)

    Hwang, Taejin; Lee, Joong Kee; Mun, Junyoung; Choi, Wonchang

    2016-08-01

    Surface-modified carbon nanotubes were utilized as a coating for LiNi0.5Mn1.5O4 (LNMO) via a mechano-fusion method as a strategy to prevent unfavorable carbothermal reduction. Two types of carbon nanotubes were investigated as coating materials: carbon nanotubes (CNTs) and oxidized carbon nanotubes (OCNTs), which were prepared by a simple re-oxidation process. The samples coated with CNTs or OCNTs were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning and transmission electron microscopy, Raman spectroscopy, and elemental analyses. The OCNT-coated LNMO presented a highly enhanced discharge capacity retention (95.5%) and a coulombic efficiency of 99.9% after 80 cycles between 3.5 and 4.9 V (versus Li/Li+), whereas the CNT-coated LNMO exhibited poor retention of 47.2% and a coulombic efficiency of 95.3%. In addition, post-mortem XPS and electrochemical impedance spectroscopy (EIS) analysis proved that the OCNT coating improved the surface electrochemical stability and rate capability, whereas the CNT coating formed a thick resistive solid electrolyte interphase (SEI) film by accelerating the surface side reactions.

  1. Ascorbic acid surface modified TiO₂-thin layers as a fully integrated analysis system for visual simultaneous detection of organophosphorus pesticides.

    Science.gov (United States)

    Li, Shunxing; Liang, Wenjie; Zheng, Fengying; Lin, Xiaofeng; Cai, Jiabai

    2014-11-06

    TiO₂ photocatalysis and colorimetric detection are coupled with thin layer chromatography (TLC) for the first time to develop a fully integrated analysis system. Titania@polystyrene hybrid microspheres were surface modified with ascorbic acid, denoted AA-TiO₂@PS, and used as the stationary phase for TLC. Because the affinity between AA-TiO₂@PS and organophosphorus pesticides (OPs) was different for different species of OPs (including chlopyrifos, malathion, parathion, parathion-methyl, and methamidophos), OPs could be separated simultaneously by the mobile phase in 12.0 min with different Rf values. After surface modification, the UV-vis wavelength response range of AA-TiO₂@PS was expanded to 650 nm. Under visible-light irradiation, all of the OPs could be photodegraded to PO₄(3-) in 25.0 min. Based on the chromogenic reaction between PO₄(3-) and chromogenic agents (ammonium molybdate and ascorbic acid), OPs were quantified from color intensity images using a scanner in conjunction with image processing software. So, AA-TiO₂@PS was respectively used as the stationary phase of TLC for efficient separation of OPs, as a photocatalyst for species transformation of phosphorus, and as a colorimetric probe for on-field simultaneous visual detection of OPs in natural water. Linear calibration curves for each OP ranged from 19.3 nmol P L(-1) to 2.30 μmol P L(-1). This integrated analysis system was simple, inexpensive, easy to operate, and sensitive.

  2. Detection of an Optical Counterpart to the ALFALFA Ultra-compact High-velocity Cloud AGC 249525

    Science.gov (United States)

    Janesh, William; Rhode, Katherine L.; Salzer, John J.; Janowiecki, Steven; Adams, Elizabeth A. K.; Haynes, Martha P.; Giovanelli, Riccardo; Cannon, John M.

    2017-03-01

    We report on the detection at >98% confidence of an optical counterpart to AGC 249525, an ultra-compact high-velocity cloud (UCHVC) discovered by the Arecibo Legacy Fast ALFA survey blind neutral hydrogen survey. UCHVCs are compact, isolated H I clouds with properties consistent with their being nearby low-mass galaxies, but without identified counterparts in extant optical surveys. Analysis of the resolved stellar sources in deep g- and I-band imaging from the WIYN pODI camera reveals a clustering of possible red giant branch stars associated with AGC 249525 at a distance of 1.64 ± 0.45 Mpc. Matching our optical detection with the H I synthesis map of AGC 249525 from Adams et al. shows that the stellar overdensity is exactly coincident with the highest-density H I contour from that study. Combining our optical photometry and the H I properties of this object yields an absolute magnitude of -7.1≤slant {M}V≤slant -4.5, a stellar mass between 2.2+/- 0.6× {10}4 {M}⊙ and 3.6+/- 1.0× {10}5 {M}⊙ , and an H I to stellar mass ratio between 9 and 144. This object has stellar properties within the observed range of gas-poor ultra-faint dwarfs in the Local Group, but is gas-dominated.

  3. Massive scalar counterpart of gravitational waves in scalarized neutron star binaries

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jing [Sun Yat-sen University, School of Physics and Astronomy, Guangzhou (China)

    2017-09-15

    In analogy with spontaneous magnetization of ferromagnets below the Curie temperature, a neutron star (NS), with a compactness above a certain critical value, may undergo spontaneous scalarization and exhibit an interior nontrivial scalar configuration. Consequently, the exterior spacetime is changed, and an external scalar field appears, which subsequently triggers a scalarization of its companion. The dynamical interplay produces a gravitational scalar counterpart of tensor gravitational waves. In this paper, we resort to scalar-tensor theory and demonstrate that the gravitational scalar counterpart from a double neutron star (DNS) and a neutron star-white dwarf (NS-WD) system become massive. We report that (1) a gravitational scalar background field, arising from convergence of external scalar fields, plays the role of gravitational scalar counterpart in scalarized DNS binary, and the appearance of a mass-dimensional constant in a Higgs-like gravitational scalar potential is responsible for a massive gravitational scalar counterpart with a mass of the order of the Planck scale; (2) a dipolar gravitational scalar radiated field, resulting from differing binding energies of NS and WD, plays the role of a gravitational scalar counterpart in scalarized orbital shrinking NS-WDs, which oscillates around a local and scalar-energy-density-dependent minimum of the gravitational scalar potential and obtains a mass of the order of about 10{sup -21} eV/c{sup 2}. (orig.)

  4. Observations of the First Electromagnetic Counterpart to a Gravitational-wave Source by the TOROS Collaboration

    Science.gov (United States)

    Díaz, M. C.; Macri, L. M.; Garcia Lambas, D.; Mendes de Oliveira, C.; Nilo Castellón, J. L.; Ribeiro, T.; Sánchez, B.; Schoenell, W.; Abramo, L. R.; Akras, S.; Alcaniz, J. S.; Artola, R.; Beroiz, M.; Bonoli, S.; Cabral, J.; Camuccio, R.; Castillo, M.; Chavushyan, V.; Coelho, P.; Colazo, C.; Costa-Duarte, M. V.; Cuevas Larenas, H.; DePoy, D. L.; Domínguez Romero, M.; Dultzin, D.; Fernández, D.; García, J.; Girardini, C.; Gonçalves, D. R.; Gonçalves, T. S.; Gurovich, S.; Jiménez-Teja, Y.; Kanaan, A.; Lares, M.; Lopes de Oliveira, R.; López-Cruz, O.; Marshall, J. L.; Melia, R.; Molino, A.; Padilla, N.; Peñuela, T.; Placco, V. M.; Quiñones, C.; Ramírez Rivera, A.; Renzi, V.; Riguccini, L.; Ríos-López, E.; Rodriguez, H.; Sampedro, L.; Schneiter, M.; Sodré, L.; Starck, M.; Torres-Flores, S.; Tornatore, M.; Zadrożny, A.

    2017-10-01

    We present the results of prompt optical follow-up of the electromagnetic counterpart of the gravitational-wave event GW170817 by the Transient Optical Robotic Observatory of the South Collaboration. We detected highly significant dimming in the light curves of the counterpart ({{Δ }}g=0.17+/- 0.03 mag, {{Δ }}r=0.14+/- 0.02 mag, {{Δ }}I=0.10+/- 0.03 mag) over the course of only 80 minutes of observations obtained ˜35 hr after the trigger with the T80-South telescope. A second epoch of observations, obtained ˜59 hr after the event with the EABA 1.5 m telescope, confirms the fast fading nature of the transient. The observed colors of the counterpart suggest that this event was a “blue kilonova” relatively free of lanthanides.

  5. Precise localizations and counterpart searches of GRBs from the 2nd interplanetary network

    International Nuclear Information System (INIS)

    Hack, F.; Hurley, K.; Atteia, J.; Barat, C.; Niel, M.; Cline, T.; Dennis, B.; Kouveliotou, C.; Klebesadel, R.; Laros, J.; Kurt, V.; Kuznetsov, A.; Zenchenko, V.

    1994-01-01

    The second interplanetary network of GRB detectors operated between 1981 and 1984. It consisted of the Venera 13 and V14 spacecraft (SIGNE detectors), PVO, ICE, and SMM (HXRBS detector). Many of the approximately 90 cosmic GRBs it detected can be localized to a high accuracy. Such localizations will make a better estimate of the burster recurrence time possible and contribute to the search for quiescent counterparts. We will present a number of localizations to illustrate the potential of this network, discuss the techniques we use to perform multi-wavelength counterpart searches, and compare present and promising future localization techniques

  6. Discovery of the optical counterpart and early optical observations of GRB 990712

    DEFF Research Database (Denmark)

    Sahu, K.C.; Vreesvijk, P.; Bakos, G.

    2000-01-01

    We present the discovery observations of the optical counterpart of the gamma-ray burst GRB 990712 taken 4.16 hr after the outburst and discuss its light curve observed in the V, R, and I bands during the first similar to 35 days after the outburst. The observed light curves were fitted with a po......We present the discovery observations of the optical counterpart of the gamma-ray burst GRB 990712 taken 4.16 hr after the outburst and discuss its light curve observed in the V, R, and I bands during the first similar to 35 days after the outburst. The observed light curves were fitted...

  7. Using Penelope to assess the correctness of NASA Ada software: A demonstration of formal methods as a counterpart to testing

    Science.gov (United States)

    Eichenlaub, Carl T.; Harper, C. Douglas; Hird, Geoffrey

    1993-01-01

    Life-critical applications warrant a higher level of software reliability than has yet been achieved. Since it is not certain that traditional methods alone can provide the required ultra reliability, new methods should be examined as supplements or replacements. This paper describes a mathematical counterpart to the traditional process of empirical testing. ORA's Penelope verification system is demonstrated as a tool for evaluating the correctness of Ada software. Grady Booch's Ada calendar utility package, obtained through NASA, was specified in the Larch/Ada language. Formal verification in the Penelope environment established that many of the package's subprograms met their specifications. In other subprograms, failed attempts at verification revealed several errors that had escaped detection by testing.

  8. Ascorbic acid surface modified TiO2-thin layers as a fully integrated analysis system for visual simultaneous detection of organophosphorus pesticides

    Science.gov (United States)

    Li, Shunxing; Liang, Wenjie; Zheng, Fengying; Lin, Xiaofeng; Cai, Jiabai

    2014-11-01

    TiO2 photocatalysis and colorimetric detection are coupled with thin layer chromatography (TLC) for the first time to develop a fully integrated analysis system. Titania@polystyrene hybrid microspheres were surface modified with ascorbic acid, denoted AA-TiO2@PS, and used as the stationary phase for TLC. Because the affinity between AA-TiO2@PS and organophosphorus pesticides (OPs) was different for different species of OPs (including chlopyrifos, malathion, parathion, parathion-methyl, and methamidophos), OPs could be separated simultaneously by the mobile phase in 12.0 min with different Rf values. After surface modification, the UV-vis wavelength response range of AA-TiO2@PS was expanded to 650 nm. Under visible-light irradiation, all of the OPs could be photodegraded to PO43- in 25.0 min. Based on the chromogenic reaction between PO43- and chromogenic agents (ammonium molybdate and ascorbic acid), OPs were quantified from color intensity images using a scanner in conjunction with image processing software. So, AA-TiO2@PS was respectively used as the stationary phase of TLC for efficient separation of OPs, as a photocatalyst for species transformation of phosphorus, and as a colorimetric probe for on-field simultaneous visual detection of OPs in natural water. Linear calibration curves for each OP ranged from 19.3 nmol P L-1 to 2.30 μmol P L-1. This integrated analysis system was simple, inexpensive, easy to operate, and sensitive.TiO2 photocatalysis and colorimetric detection are coupled with thin layer chromatography (TLC) for the first time to develop a fully integrated analysis system. Titania@polystyrene hybrid microspheres were surface modified with ascorbic acid, denoted AA-TiO2@PS, and used as the stationary phase for TLC. Because the affinity between AA-TiO2@PS and organophosphorus pesticides (OPs) was different for different species of OPs (including chlopyrifos, malathion, parathion, parathion-methyl, and methamidophos), OPs could be separated

  9. Investigation of γ-(2,3-Epoxypropoxy)propyltrimethoxy Silane Surface Modified Layered Double Hydroxides Improving UV Ageing Resistance of Asphalt

    Science.gov (United States)

    Zhang, Canlin; Yu, Jianying; Xue, Lihui; Sun, Yubin

    2017-01-01

    γ-(2,3-Epoxypropoxy)propyltrimethoxy silane surface modified layered double hydroxides (KH560-LDHs) were prepared and used to improve the ultraviolet ageing resistance of asphalt. The results of X-ray photoelectron spectrometry (XPS) indicated that KH560 has been successfully grafted onto the surface of LDHs. The agglomeration of LDHs particles notably reduced after KH560 surface modification according to scanning electron microscopy (SEM), which implied that the KH560 surface modification was helpful to promote the dispersibility of LDHs in asphalt. Then, the influence of KH560-LDHs and LDHs on the physical and rheological properties of asphalt before and after UV ageing was thoroughly investigated. The storage stability test showed that the difference in softening point (ΔS) of LDHs modified asphalt decreased from 0.6 °C to 0.2 °C at an LDHs content of 1% after KH560 surface modification, and the tendency became more pronounced with the increase of LDH content, indicating that KH560 surface modification could improve the stability of LDHs in asphalt. After UV ageing, the viscous modulus (G’’) of asphalt significantly reduced, and correspondingly, the elastic modulus (G’) and rutting factor (G*/sin δ) rapidly increased. Moreover, the asphaltene increased and the amount of “bee-like” structures of the asphalt decreased. Compared with LDHs, KH560-LDHs obviously restrained performance deterioration of the asphalt, and helped to relieve the variation of the chemical compositions and morphology of asphalt, which suggested that the improvement of KH560-LDHs on UV ageing resistance of asphalt was superior to LDHs. PMID:28772438

  10. Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution.

    Science.gov (United States)

    Líbalová, Helena; Costa, Pedro M; Olsson, Magnus; Farcal, Lucian; Ortelli, Simona; Blosi, Magda; Topinka, Jan; Costa, Anna L; Fadeel, Bengt

    2018-04-01

    The rapid dissolution of copper oxide (CuO) nanoparticles (NPs) with release of ions is thought to be one of the main factors modulating their toxicity. Here we assessed the cytotoxicity of a panel of CuO NPs (12 nm ± 4 nm) with different surface modifications, i.e., anionic sodium citrate (CIT) and sodium ascorbate (ASC), neutral polyvinylpyrrolidone (PVP), and cationic polyethylenimine (PEI), versus the pristine (uncoated) NPs, using a murine macrophage cell line (RAW264.7). Cytotoxicity, reactive oxygen species (ROS) production, and cellular uptake were assessed. The cytotoxicity results were analyzed by the benchmark dose (BMD) method and the NPs were ranked based on BMD 20 values. The PEI-coated NPs were found to be the most cytotoxic. Despite the different properties of the coating agents, NP dissolution in cell medium was only marginally affected by surface modification. Furthermore, CuCl 2 (used as an ion control) elicited significantly less cytotoxicity when compared to the CuO NPs. We also observed that the antioxidant, N-acetylcysteine, failed to protect against the cytotoxicity of the uncoated CuO NPs. Indeed, the toxicity of the surface-modified CuO NPs was not directly linked to particle dissolution and subsequent Cu burden in cells, nor to cellular ROS production, although CuO-ASC NPs, which were found to be the least cytotoxic, yielded lower levels of ROS in comparison to pristine NPs. Hierarchical cluster analysis suggested, instead, that the toxicity in the current in vitro model could be explained by synergistic interactions between the NPs, their dissolution, and the toxicity of the coating agents. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Counterpart experimental study of ISP-42 PANDA tests on PUMA facility

    International Nuclear Information System (INIS)

    Yang, Jun; Choi, Sung-Won; Lim, Jaehyok; Lee, Doo-Yong; Rassame, Somboon; Hibiki, Takashi; Ishii, Mamoru

    2013-01-01

    Highlights: ► Counterpart tests were performed on two large-scale BWR integral facilities. ► Similarity of post-LOCA system behaviors observed between two tests. ► Passive core and containment cooling systems work as design in both tests. -- Abstract: A counterpart test to the Passive Nachwärmeabfuhr und Druckabbau Test Anlage (Passive Decay Heat Removal and Depressurization Test Facility, PANDA) International Standard Problem (ISP)-42 test was conducted at the Purdue University Multi-Dimensional Integral Test Assembly (PUMA) facility. Aimed to support code validation on a range of light water reactor (LWR) containment issues, the ISP-42 test consists of six sequential phases (Phases A–F) with separately defined initial and boundary conditions, addressing different stages of anticipated accident scenario and system responses. The counterpart test was performed from Phases A to D, which are within the scope of the normal integral tests performed on the PUMA facility. A scaling methodology was developed by using the PANDA facility as prototype and PUMA facility as test model, and an engineering scaling has been applied to the PUMA facility. The counterpart test results indicated that functions of passive safety systems, such as passive containment cooling system (PCCS) start-up, gravity-driven cooling system (GDCS) discharge, PCCS normal operation and overload function were confirmed in both the PANDA and PUMA facilities with qualitative similarities

  12. Nano-Scale Interface Modification of the Co/Cu System: Metallic Surface Modifiers in the Growth of Smooth Thin Films

    International Nuclear Information System (INIS)

    Wolny-Marszalek, M.

    2007-10-01

    This review is a collection of twelve original papers concerning growth and interface modification in the Co/Cu system. Most of this research has been carried out in the Laboratory of Surface and Thin Film Physics at the Institute of Nuclear Physics. The Laboratory was created by the author of this review in 1996 in strong collaboration with the Institute of Nuclear Physics Wilhelms-Universitaet in Muenster, Germany and the Institute of Applied Physics Ukrainian Academy of Science in Sumy, Ukraine. The big international team worked under the leadership of Dr Marta Marszalek, initially developing a multicomponent ultrahigh vacuum setup for thin film preparation and analysis, and next accompanying her in studies of the structural, magnetic and magnetotransport properties of Co/Cu multilayers. Systems that exhibit giant magnetoresistance effect have been receiving intensive attentions over recent years since they are possible candidates for applications in ultrahigh-density data storage and magnetoelectronic devices. The focus of this research is the growth of magnetic Co/Cu multilayers modified by using metallic surface modifiers called surfactants. The different approaches have been used. Surfactant metals were introduced once into growth process as a buffer layer or they were deposited sequentially at each interface of Co/Cu multilayers. The growth was performed by molecular beam epitaxy technique which allows to tailor carefully deposition conditions. The results showed that two approaches gave different results. Surfactant buffer layers resulted in loss of layered character of multilayers being a kind of an intermediate cluster-like phase combined with a layered area. Small amount of surfactants introduced at each interface lead to well-ordered structures with small roughness and smoother interfaces than in the case of pure Co/Cu multilayers. Despite of the differences, in both cases the improvement of magnetoresistance value was observed. The atomic scale study

  13. Influence of the way of synthesis of poly(methyl methacrylate in the presence of surface modified TiO2 nanoparticles on the properties of obtained nanocomposites

    Directory of Open Access Journals (Sweden)

    Džunuzović Enis S.

    2010-01-01

    Full Text Available Incorporation of inorganic nanoparticles can significantly affect the properties of the polymer matrix. The properties of polymer nanocomposites depend on the type of incorporated nanoparticles, their size and shape, their concentration, and interactions with the polymer matrix. Homogeneity of polymer nanocomposites is influenced very much by the preparation method. In this study, TiO2 nanoparticles surface modified with 6-palmitate ascorbic acid (6-PAA were incapsulated in poly(methyl methacrylate (PMMA by in situ radical polymerization of methyl methacrylate initiated by 2,2'-azobisisobutyronitrile (AIBN. The surface modification of the TiO2 nanoparticles was achieved by the formation of a charge transfer complex between TiO2 nanoparticles and 6-palmitate ascorbic acid. The radical polymerization of MMA in the presence of TiO2-PAA nanoparticles was conducted in solution (PMMA/TiO2-PAA-R, in bulk (PMMA/TiO2-PAA-M or in suspension (PMMA/TiO2-PAA-S. The main purpose of this study was to investigate the influence of the preparation method on the molar masses and thermal properties of PMMA/TiO2-PAA nanocomposite. It was obtained that molar masses of PMMA extracted from the composites had smaller values compared to molar masses of pure PMMA synthesized in the same manner, which indicated that TiO2-PAA nanoparticles affected the reaction of termination. Thermal properties were investigated by DSC and TGA. The values of glass transition temperature, Tg, were influenced by the way the radical polymerization was conducted, even in the case of the pure PMMA. The Tg of composite samples was always smaller than the value of the corresponding PMMA sample and the smallest value was obtained for PMMA/TiO2-PAA-M since they contained the largest amount of low molar mass residue. The TGA results showed that thermal and thermooxidative stability of polymer composites obtained in solution and in suspension was better than for the pure PMMA obtained in the same way.

  14. IDENTIFYING ELUSIVE ELECTROMAGNETIC COUNTERPARTS TO GRAVITATIONAL WAVE MERGERS: AN END-TO-END SIMULATION

    International Nuclear Information System (INIS)

    Nissanke, Samaya; Georgieva, Alexandra; Kasliwal, Mansi

    2013-01-01

    Combined gravitational wave (GW) and electromagnetic (EM) observations of compact binary mergers should enable detailed studies of astrophysical processes in the strong-field gravity regime. This decade, ground-based GW interferometers promise to routinely detect compact binary mergers. Unfortunately, networks of GW interferometers have poor angular resolution on the sky and their EM signatures are predicted to be faint. Therefore, a challenging goal will be to unambiguously pinpoint the EM counterparts of GW mergers. We perform the first comprehensive end-to-end simulation that focuses on: (1) GW sky localization, distance measures, and volume errors with two compact binary populations and four different GW networks; (2) subsequent EM detectability by a slew of multiwavelength telescopes; and (3) final identification of the merger counterpart amidst a sea of possible astrophysical false positives. First, we find that double neutron star binary mergers can be detected out to a maximum distance of 400 Mpc (or 750 Mpc) by three (or five) detector GW networks, respectively. Neutron-star-black-hole binary mergers can be detected a factor of 1.5 further out; their median to maximum sky localizations are 50-170 deg 2 (or 6-65 deg 2 ) for a three (or five) detector GW network. Second, by optimizing depth, cadence, and sky area, we quantify relative fractions of optical counterparts that are detectable by a suite of different aperture-size telescopes across the globe. Third, we present five case studies to illustrate the diversity of scenarios in secure identification of the EM counterpart. We discuss the case of a typical binary, neither beamed nor nearby, and the challenges associated with identifying an EM counterpart at both low and high Galactic latitudes. For the first time, we demonstrate how construction of low-latency GW volumes in conjunction with local universe galaxy catalogs can help solve the problem of false positives. We conclude with strategies that would

  15. Bimodal Long-lasting Components in Short Gamma-Ray Bursts: Promising Electromagnetic Counterparts to Neutron Star Binary Mergers

    Energy Technology Data Exchange (ETDEWEB)

    Kisaka, Shota; Sakamoto, Takanori [Department of Physics and Mathematics, Aoyama Gakuin University, Sagamihara, Kanagawa, 252-5258 (Japan); Ioka, Kunihito, E-mail: kisaka@phys.aoyama.ac.jp, E-mail: tsakamoto@phys.aoyama.ac.jp, E-mail: kunihito.ioka@yukawa.kyoto-u.ac.jp [Center for Gravitational Physics, Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan)

    2017-09-10

    Long-lasting emission of short gamma-ray bursts (GRBs) is crucial to reveal the physical origin of the central engine as well as to detect electromagnetic (EM) counterparts to gravitational waves (GWs) from neutron star binary mergers. We investigate 65 X-ray light curves of short GRBs, which is six times more than previous studies, by combining both Swift /BAT and XRT data. The light curves are found to consist of two distinct components at >5 σ with bimodal distributions of luminosity and duration, i.e., extended (with a timescale of ≲10{sup 3} s) and plateau emission (with a timescale of ≳10{sup 3} s), which are likely the central engine activities, but not afterglows. The extended emission has an isotropic energy comparable to the prompt emission, while the plateau emission has ∼0.01–1 times this energy. Half (50%) of our sample has both components, while the other half is consistent with having both components. This leads us to conjecture that almost all short GRBs have both the extended and plateau emission. The long-lasting emission can be explained by the jets from black holes with fallback ejecta, and could power macronovae (or kilonovae) like GRB 130603B and GRB 160821B. Based on the observed properties, we quantify the detectability of EM counterparts to GWs, including the plateau emission scattered to the off-axis angle, with CALET /HXM, INTEGRAL /SPI-ACS, Fermi /GBM, MAXI /GSC, Swift /BAT, XRT, the future ISS-Lobster /WFI, Einstein Probe /WXT, and eROSITA .

  16. Discovery, Follow-up, and Implications of the Optical/Infrared Counterpart to GW170817

    Science.gov (United States)

    Drout, Maria

    2018-01-01

    On August 17th, 2017, the field of multi-messenger, gravitational-wave, astronomy was born. On this date, Advanced LIGO and Advanced Virgo observed gravitational waves from the coalescence of a neutron star binary with a false alarm probability of 1 per 10000 years and electromagnetic counterparts were subsequently identified across the entire electromagnetic spectrum. In this talk, I will give a broad review of the optical and infrared emission associated with the binary neutron star merger, GW170817. I will describe the process of the discovery and localization of the optical counterpart, and review the extensive follow-up observations obtained over the following three weeks. Finally, I will place these results in context. I will discuss the implications of these observations on our understanding of the ejecta from neutron star mergers, the origin of r-process elements, and the prospects for the identification of similar transients in upcoming surveys.

  17. The prompt acquisition of gamma ray optical counterparts with the Bradford Robotic Telescope

    Science.gov (United States)

    Baruch, J. E. F.; Bennett, C.; Cox, M. J.; Davis, R.

    1996-08-01

    The Bradford Robotic Telescope was conceived as an instrument to work with observers in other wavebands and specifically to monitor gamma sources and acquire optical counterparts to gamma-bursters. Its main line of support has been to provide an automated robotic photometry service on the Internet. Its first light was in the autumn of 1993. The telescope and its development are described (http://www.telescope.org/rti). The development of instrumentation for astronomy in an engineering department is discussed and the evolution of the networking and communications is described to the point where a fast link to the Internet BACODINE system can be achieved. The current performance is detailed with estimates of its efficiency. Images of BATSE error boxes are discussed. Current plans are to better match the field of the telescope to the BATSE error boxes and to monitor optical counterparts on a fractional second time scale.

  18. HST/ACS Imaging of Omega Centauri: Optical Counterparts of Chandra X-Ray Sources

    Science.gov (United States)

    Cool, Adrienne M.; Haggard, Daryl; Arias, Tersi; Brochmann, Michelle; Dorfman, Jason; Gafford, April; White, Vivian; Anderson, Jay

    2013-02-01

    We present results of a search for optical counterparts of X-ray sources in and toward the globular cluster Omega Centauri (NGC 5139) using the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope. The ACS data consist of a mosaic of Wide Field Channel images obtained using F625W, F435W, and F658N filters; with nine pointings we cover the central ~10' × 10' of the cluster and encompass 109 known Chandra sources. We find promising optical counterparts for 59 of the sources, ~40 of which are likely to be associated with the cluster. These include 27 candidate cataclysmic variables (CVs), 24 of which are reported here for the first time. Fourteen of the CV candidates are very faint, with absolute magnitudes in the range M 625 =10.4-12.6, making them comparable in brightness to field CVs near the period minimum discovered in the Sloan Digital Sky Survey. Additional optical counterparts include three BY Dra candidates, a possible blue straggler, and a previously reported quiescent low-mass X-ray binary. We also identify 3 foreground stars and 11 probable active galactic nuclei. Finally, we report the discovery of a group of seven stars whose X-ray properties are suggestive of magnetically active binaries, and whose optical counterparts lie on or very near the metal-rich anomalous giant and subgiant branches in ω Cen. If the apparent association between these seven stars and the RGB/SGB-a stars is real, then the frequency of X-ray sources in this metal-rich population is enhanced by a factor of at least five relative to the other giant and subgiant populations in the cluster. If these stars are not members of the metal-rich population, then they bring the total number of red stragglers (also known as sub-subgiants) that have been identified in ω to Cen 20, the largest number yet known in any globular cluster.

  19. Finding X-ray counterparts for unidentified sources in the 105 months BAT survey - 1

    Science.gov (United States)

    Stephen, J. B.; Bassani, L.; Malizia, A.; Masetti, N.; Ubertini, P.

    2018-02-01

    We provide X-ray counterparts for the unidentified Swift/BAT sources listed in the 105 month catalogue (Oh et al. 2018, ApJS in press). These associations were found by cross-correlating the list of U1,U2 and U3 sources with the ROSAT Bright (RASSBSC, Voges et al. 1999, A & A, 349, 389) and the XMM-Newton Slew (XMMSlew, Saxton et al. 2008, A & A, 480, 611) catalogues.

  20. Finding X-ray counterparts for unidentified sources in the 105 months BAT survey - 2

    Science.gov (United States)

    Stephen, J. B.; Bassani, L.; Malizia, A.; Masetti, N.; Ubertini, P.

    2018-02-01

    We provide X-ray counterparts for unidentified Swift/BAT sources in the 105 month catalogue (Oh et al. 2018, ApJS in press). They were found by cross-correlating the list of U1,U2 and U3 sources with the ROSAT Bright (RASSBSC, Voges et al. 1999, A & A, 349, 389) and XMM-Newton Slew (XMMSlew, Saxton et al. 2008, A & A, 480, 611) catalogues and optically identified as reported in Atel #11340.

  1. Strategic Wholesale Pricing for an Incumbent Supplier Facing with a Competitive Counterpart

    OpenAIRE

    Sun, Jianwu

    2014-01-01

    We introduce a wholesale pricing strategy for an incumbent supplier facing with a competitive counterpart. We propose a profit function which considers both the present loss and future loss from a wholesale price and then study the optimal wholesale prices for different objectives about this profit function for the incumbent supplier. First, we achieve an optimal wholesale price for the incumbent supplier to maximize his expected profit. Then, to reduce the risk originating from the fluctuati...

  2. Counterpart synchronization of duplex networks with delayed nodes and noise perturbation

    International Nuclear Information System (INIS)

    Wei, Xiang; Wu, Xiaoqun; Lu, Jun-an; Zhao, Junchan

    2015-01-01

    In the real world, many complex systems are represented not by single networks but rather by sets of interdependent ones. In these specific networks, nodes in one network mutually interact with nodes in other networks. This paper focuses on a simple representative case of two-layer networks (the so-called duplex networks) with unidirectional inter-layer couplings. That is, each node in one network depends on a counterpart in the other network. Accordingly, the former network is called the response layer and the latter network is the drive layer. Specifically, synchronization between each node in the drive layer and its counterpart in the response layer (counterpart synchronization (CS)) in these kinds of duplex networks with delayed nodes and noise perturbation is investigated. Based on the LaSalle-type invariance principle, a control technique is proposed and a sufficient condition is developed for realizing CS of duplex networks. Furthermore, two corollaries are derived as special cases. In addition, node dynamics within each layer can be varied and topologies of the two layers are not necessarily identical. Therefore, the proposed synchronization method can be applied to a wide range of multiplex networks. Numerical examples are provided to illustrate the feasibility and effectiveness of the results. (paper)

  3. HST/ACS IMAGING OF OMEGA CENTAURI: OPTICAL COUNTERPARTS OF CHANDRA X-RAY SOURCES

    International Nuclear Information System (INIS)

    Cool, Adrienne M.; Arias, Tersi; Brochmann, Michelle; Dorfman, Jason; Gafford, April; White, Vivian; Haggard, Daryl; Anderson, Jay

    2013-01-01

    We present results of a search for optical counterparts of X-ray sources in and toward the globular cluster Omega Centauri (NGC 5139) using the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope. The ACS data consist of a mosaic of Wide Field Channel images obtained using F625W, F435W, and F658N filters; with nine pointings we cover the central ∼10' × 10' of the cluster and encompass 109 known Chandra sources. We find promising optical counterparts for 59 of the sources, ∼40 of which are likely to be associated with the cluster. These include 27 candidate cataclysmic variables (CVs), 24 of which are reported here for the first time. Fourteen of the CV candidates are very faint, with absolute magnitudes in the range M 625 =10.4-12.6, making them comparable in brightness to field CVs near the period minimum discovered in the Sloan Digital Sky Survey. Additional optical counterparts include three BY Dra candidates, a possible blue straggler, and a previously reported quiescent low-mass X-ray binary. We also identify 3 foreground stars and 11 probable active galactic nuclei. Finally, we report the discovery of a group of seven stars whose X-ray properties are suggestive of magnetically active binaries, and whose optical counterparts lie on or very near the metal-rich anomalous giant and subgiant branches in ω Cen. If the apparent association between these seven stars and the RGB/SGB-a stars is real, then the frequency of X-ray sources in this metal-rich population is enhanced by a factor of at least five relative to the other giant and subgiant populations in the cluster. If these stars are not members of the metal-rich population, then they bring the total number of red stragglers (also known as sub-subgiants) that have been identified in ω to Cen 20, the largest number yet known in any globular cluster.

  4. Understanding possible electromagnetic counterparts to loud gravitational wave events: Binary black hole effects on electromagnetic fields

    International Nuclear Information System (INIS)

    Palenzuela, Carlos; Lehner, Luis; Yoshida, Shin

    2010-01-01

    In addition to producing loud gravitational waves, the dynamics of a binary black hole system could induce emission of electromagnetic radiation by affecting the behavior of plasmas and electromagnetic fields in their vicinity. We study how the electromagnetic fields are affected by a pair of orbiting black holes through the merger. In particular, we show how the binary's dynamics induce a variability in possible electromagnetically induced emissions as well as an enhancement of electromagnetic fields during the late-merge and merger epochs. These time dependent features will likely leave their imprint in processes generating detectable emissions and can be exploited in the detection of electromagnetic counterparts of gravitational waves.

  5. Observations of optical counterparts of high-energy sources with ESA Gaia

    Czech Academy of Sciences Publication Activity Database

    Hudec, René; Šimon, Vojtěch; Hudec, L.

    2008-01-01

    Roč. 8, spec. iss. (2008), s. 386-392 ISSN 1009-9271. [International workshop on multifrequency behaviour of high energy cosmic sources. Vulcano, 28.05.2007-02.06.2007] R&D Projects: GA AV ČR IAA3003206; GA ČR GA205/05/2167 Grant - others:ESA(XE) ESA-PECS project No. 98023; ESA(CZ) ESA-PECS project No. 98058 Institutional research plan: CEZ:AV0Z10030501 Keywords : high-energy sources * optical counterparts Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 0.689, year: 2008

  6. Do Lower Calorie or Lower Fat Foods Have More Sodium Than Their Regular Counterparts?

    Directory of Open Access Journals (Sweden)

    Katherine A. John

    2016-08-01

    Full Text Available The objective of this study was to compare the sodium content of a regular food and its lower calorie/fat counterpart. Four food categories, among the top 20 contributing the most sodium to the US diet, met the criteria of having the most matches between regular foods and their lower calorie/fat counterparts. A protocol was used to search websites to create a list of “matches”, a regular and comparable lower calorie/fat food(s under each brand. Nutrient information was recorded and analyzed for matches. In total, 283 matches were identified across four food categories: savory snacks (N = 44, cheese (N = 105, salad dressings (N = 90, and soups (N = 44. As expected, foods modified from their regular versions had significantly reduced average fat (total fat and saturated fat and caloric profiles. Mean sodium content among modified salad dressings and cheeses was on average 8%–12% higher, while sodium content did not change with modification of savory snacks. Modified soups had significantly lower mean sodium content than their regular versions (28%–38%. Consumers trying to maintain a healthy diet should consider that sodium content may vary in foods modified to be lower in calories/fat.

  7. Probing extra dimension through gravitational wave observations of compact binaries and their electromagnetic counterparts

    Science.gov (United States)

    Yu, Hao; Gu, Bao-Min; Huang, Fa Peng; Wang, Yong-Qiang; Meng, Xin-He; Liu, Yu-Xiao

    2017-02-01

    The future gravitational wave (GW) observations of compact binaries and their possible electromagnetic counterparts may be used to probe the nature of the extra dimension. It is widely accepted that gravitons and photons are the only two completely confirmed objects that can travel along null geodesics in our four-dimensional space-time. However, if there exist extra dimensions and only GWs can propagate freely in the bulk, the causal propagations of GWs and electromagnetic waves (EMWs) are in general different. In this paper, we study null geodesics of GWs and EMWs in a five-dimensional anti-de Sitter space-time in the presence of the curvature of the universe. We show that for general cases the horizon radius of GW is longer than EMW within equal time. Taking the GW150914 event detected by the Advanced Laser Interferometer Gravitational-Wave Observatory and the X-ray event detected by the Fermi Gamma-ray Burst Monitor as an example, we study how the curvature k and the constant curvature radius l affect the horizon radii of GW and EMW in the de Sitter and Einstein-de Sitter models of the universe. This provides an alternative method for probing extra dimension through future GW observations of compact binaries and their electromagnetic counterparts.

  8. Off-axis short GRBs from structured jets as counterparts to GW events

    Science.gov (United States)

    Kathirgamaraju, Adithan; Barniol Duran, Rodolfo; Giannios, Dimitrios

    2018-01-01

    Binary neutron star mergers are considered to be the most favourable sources that produce electromagnetic (EM) signals associated with gravitational waves (GWs). These mergers are the likely progenitors of short duration gamma-ray bursts (GRBs). The brief gamma-ray emission (the 'prompt' GRB emission) is produced by ultrarelativistic jets, as a result, this emission is strongly beamed over a small solid angle along the jet. It is estimated to be a decade or more before a short GRB jet within the Laser Interferometer Gravitational-Wave observatory (LIGO) volume points along our line of sight. For this reason, the study of the prompt signal as an EM counterpart to GW events has been sparse. We argue that for a realistic jet model, one whose luminosity and Lorentz factor vary smoothly with angle, the prompt signal can be detected for a significantly broader range of viewing angles. This can lead to an 'off-axis' short GRB as an EM counterpart. Our estimates and simulations show that it is feasible to detect these signals with the aid of the temporal coincidence from a LIGO trigger, even if the observer is substantially misaligned with respect to the jet.

  9. A CANDIDATE OPTICAL COUNTERPART TO THE MIDDLE AGED γ -RAY PULSAR PSR J1741–2054

    Energy Technology Data Exchange (ETDEWEB)

    Mignani, R. P.; Marelli, M.; Luca, A. De; Salvetti, D.; Belfiore, A. [INAF—Istituto di Astrofisica Spaziale e Fisica Cosmica Milano, via E. Bassini 15, I-20133, Milano (Italy); Testa, V. [INAF—Osservatorio Astronomico di Roma, via Frascati 33, I-00040, Monteporzio (Italy); Pierbattista, M. [Department of Astrophysics and Theory of Gravity, Maria Curie-Sklodowska University, ul. Radziszewskiego 10, 20-031 Lublin (Poland); Razzano, M. [Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, I-56127 Pisa (Italy); Shearer, A.; Moran, P. [Centre for Astronomy, National University of Ireland, Newcastle Road, Galway (Ireland)

    2016-07-10

    We carried out deep optical observations of the middle aged γ -ray pulsar PSR J1741−2054 with the Very Large Telescope (VLT). We identified two objects, of magnitudes m {sub v} = 23.10 ± 0.05 and m {sub v} = 25.32 ± 0.08, at positions consistent with the very accurate Chandra coordinates of the pulsar, the faintest of which is more likely to be its counterpart. From the VLT images we also detected the known bow-shock nebula around PSR J1741−2054. The nebula is displaced by ∼0.″9 (at the 3 σ confidence level) with respect to its position measured in archival data, showing that the shock propagates in the interstellar medium consistently with the pulsar proper motion. Finally, we could not find evidence of large-scale extended optical emission associated with the pulsar wind nebula detected by Chandra , down to a surface brightness limit of ∼28.1 mag arcsec{sup −2}. Future observations are needed to confirm the optical identification of PSR J1741−2054 and characterize the spectrum of its counterpart.

  10. Characterization of maize allergens - MON810 vs. its non-transgenic counterpart.

    Science.gov (United States)

    Fonseca, Cátia; Planchon, Sébastien; Renaut, Jenny; Oliveira, Maria Margarida; Batista, Rita

    2012-04-03

    One of the main concerns about genetically modified foods and their potential impacts on human health is that the introduction of a new/ altered gene may putatively alter the expression of others, namely endogenous allergens. We intended to evaluate, and to compare, using quantitative real time RT-PCR technique, the expression of 5 already known maize allergens (Zea m14, Zea m25, Zea m27kD, 50kD Zein and trypsin inhibitor) in MON 810 vs. its non-transgenic counterpart, throughout seed development (10, 16 and 23days after pollination). We have shown that none of the tested allergen genes presented differential expression, with statistic significance, along all tested seed development stages, in MON810 vs. its conventional counterpart. We have also used bidimensional gel electrophoresis followed by Western blotting with plasma from two maize allergic subjects to characterize their immunologic responses against MON 810 vs. its non-transgenic control. Immunoreactive spots were characterized by MS. We have identified fourteen new IgE-binding proteins present in both transgenic and non-transgenic maize. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Acute mixture toxicity of halogenated chemicals and their next generation counterparts on zebrafish embryos.

    Science.gov (United States)

    Godfrey, Amy; Abdel-Moneim, Ahmed; Sepúlveda, Maria S

    2017-08-01

    Perfluorinated chemicals and flame retardants are halogenated compounds commonly used in food packaging and in clothing and electronics, respectively. Due to the hazardous effects of many of these chemicals, manufacturers are developing next generation potential less toxic alternatives. The objective of this study was to assess the toxicity of potentially "safer" alternatives, singly and in mixtures, in relation to their first generation counterparts. We used zebrafish embryos as our model organism due to its high structural and functional homology to other vertebrates and its suitability for early developmental studies. We tested three well studied halogens, perfluorooctanoic acid (PFOA), tris (1,3-dichloro-2-propyl) phosphate (TDCPP) and tetrabromobisphenal A (TBBPA), and two less-studied next generation chemicals, 9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO) and perfluorobutyric acid (PFBA). First, we identified their lethal concentration (LC 50 ) under 96 h exposures using zebrafish embryos; chemical LC50 values ranged from 1.3 to 13,795 ppm. Next, we tested the toxicity of tertiary mixtures containing the estimated LC 50 values for each chemical which ranged from 126 to 5,094 ppm. We found that chemicals within these mixtures displayed concentration addition suggesting a similar mode of toxic action. Importantly, next generation chemicals were less acutely toxic singly and in mixtures than their first generation counterpart. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Tribological Response of Heat Treated AISI 52100 Steels Against Steel and Ceramic Counterparts

    Directory of Open Access Journals (Sweden)

    Türedi E.

    2017-09-01

    Full Text Available AISI 52100 bearing steels are commonly used in applications requiring high hardness and abrasion resistance. The bearing steels are working under dynamic loads in service conditions and their toughness properties become important. In order to provide the desired mechanical properties, various heat treatments (austenizing, quenching and tempering are usually applied. In this study, AISI 52100 bearing steel samples were austenized at 900°C for ½ h and water quenched to room temperature. Then tempering was carried out at 795°C, 400°C and 200°C for ½ h. In order to investigate the effect of heat treatment conditions on wear behavior, dry friction tests were performed according to ASTM G99-05 Standard with a ‘ball-on-disk’ type tribometer. The samples were tested against steel and ceramic counterparts using the parameters of 100 m distance and 30 N load and 0.063 m/s rotational speed. After wear test, the surface characterization was carried out using microscopy. Wear loss values were calculated using a novel optical method on both flat and counterpart specimens.

  13. THE VARIABLE NEAR-INFRARED COUNTERPART OF THE MICROQUASAR GRS 1758–258

    Energy Technology Data Exchange (ETDEWEB)

    Luque-Escamilla, Pedro L. [Departamento de Ingeniería Mecánica y Minera, EPSJ, Universidad de Jaén, Campus Las Lagunillas s/n, A3-008, 23071 Jaén (Spain); Martí, Josep [Departamento de Física, EPSJ, Universidad de Jaén, Campus Las Lagunillas s/n, A3-420, 23071 Jaén (Spain); Muñoz-Arjonilla, Álvaro J., E-mail: peter@ujaen.es, E-mail: jmarti@ujaen.es, E-mail: ajmunoz@ujaen.es [Grupo de Investigación FQM-322, Universidad de Jaén, Campus Las Lagunillas s/n, A3-065, 23071 Jaén (Spain)

    2014-12-10

    We present a new study of the microquasar system GRS 1758–258 in the near-infrared domain based on archival observations with the Hubble Space Telescope and the NICMOS camera. In addition to confirming the near-infrared counterpart pointed out by Muñoz-Arjonilla et al., we show that this object displays significant photometric variability. From its average magnitudes, we also find that GRS 1758–258 fits well within the correlation between the optical/near-infrared and X-ray luminosity known to exist for low-mass, black-hole candidate X-ray binaries in a hard state. Moreover, the spectral energy distribution built using all radio, near-infrared, and X-ray data available closest in time to the NICMOS observations can be reasonably interpreted in terms of a self-absorbed radio jet and an irradiated accretion disk model around a stellar-mass black hole. All these facts match the expected behavior of a compact binary system and strengthen our confidence in the counterpart identification.

  14. Preparation and Evaluation of Dexamethasone (DEX/Growth and Differentiation Factor-5 (GDF-5 Surface-Modified Titanium Using β-Cyclodextrin-Conjugated Heparin (CD-Hep for Enhanced Osteogenic Activity In Vitro and In Vivo

    Directory of Open Access Journals (Sweden)

    Dae Hyeok Yang

    2017-08-01

    Full Text Available The most ideal implant models in the dental and orthopedic fields to minimize the failure rate of implantation involve the improvement of osseointegration with host bone. Therefore, a focus of this study is the preparation of surface-modified titanium (Ti samples of disc and screw types using dexamethasone (DEX and/or growth and differentiation factor-5 (GDF-5, as well as the evaluation of their efficacies on bone formation in vitro and in vivo. X-ray photoelectron spectroscopy (XPS, scanning electron microscopy (SEM and contact angle measurement were used to evaluate the surface chemical composition, surface morphology and wettability, respectively. The results showed that implant surfaces were successfully modified with DEX and/or GDF-5, and had rough surfaces along with hydrophilicity. DEX, GDF-5 or DEX/GDF-5 on the surface-modified samples were rapidly released within one day and released for 28 days in a sustained manner. The proliferation and bone formation of MC3T3-E1 cells cultured on pristine and surface-modified implants in vitro were examined by cell counting kit-8 (CCK-8 assay, as well as the measurements of alkaline phosphatase (ALP activity and calcium deposition, respectively. MC3T3-E1 cells cultured on DEX/GDF-5–Ti showed noticeable ALP activity and calcium deposition in vitro. Active bone formation and strong osseointegration occurred at the interface between DEX/GDF-5–Ti and host bone, as evaluated by micro computed-tomography (micro CT analysis. Surface modification using DEX/GDF-5 could be a good method for advanced implants for orthopaedic and dental applications.

  15. Strategies for Prompt Searches for GRB Afterglows: The Discovery of GRB 001011 Optical/Near-Infrared Counterpart Using Colour-Colour Selection

    Science.gov (United States)

    Gorosabel, J.; Fynbo, J. U.; Hjorth, J.; Wolf, C.; Andersen, M. I.; Pedersen, H.; Christensen, L.; Jensen, B. L.; Moller, P.; Afonso, J.; hide

    2001-01-01

    We report the discovery of the optical and near-infrared counterpart to GRB 001011. The GRB 001011 error box determined by Beppo-SAX was simultaneously imaged in the near-infrared by the 3.58-m. New Technology Telescope and in the optical by the 1.54-m Danish Telescope - 8 hr after the gamma-ray event. We implement the colour-colour discrimination technique proposed by Rhoads (2001) and extend it using near-IR data as well. We present the results provided by an automatic colour-colour discrimination pipe-line developed to discern the different populations of objects present in the GRB 001011 error box. Our software revealed three candidates based on single-epoch images. Second-epoch observations carried out approx. 3.2 days after the burst revealed that the most likely candidate had faded thus identifying it with the counterpart to the GRB. In deep R-band images obtained 7 months after the burst a faint (R=25.38 plus or minus 0.25) elongated object, presumably the host galaxy of GRB 001011, was detected at the position of the afterglow. The GRB 001011 afterglow is the first discovered with the assistance of colour-colour diagram techniques. We discuss the advantages of using this method and its application to boxes determined by future missions.

  16. Experiment data report for semiscale Mod-1 Test S-06-2 (LOFT counterpart test). [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Patton, Jr., M. L.; Collins, B. L.; Sackett, K. E.

    1977-08-01

    Recorded test data are presented for Test S-06-2 of the Semiscale Mod-1 LOFT counterpart test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying an hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-06-2 was conducted from initial conditions of 15 513 kPa and 563 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact loop to simulate emergency core coolant injection in a PWR. The heater rods in the electrically heated core were operated at an axial peak power density which was 50% of the maximum peak power density (52.5 kW/m).

  17. Experiment data report for semiscale Mod-1 test S-06-1 (LOFT counterpart test). [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Collins, B. L.; Patton, Jr., M. L.; Sackett, K. E.

    1977-07-01

    Recorded test data are presented for Test S-06-1 of the Semiscale Mod-1 LOFT counterpart test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying an hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-06-1 was conducted from initial conditions of 15 568 kPa and 564 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact loop to simulate emergency core coolant injection in a PWR. The heater rods in the electrically heated core were operated at an axial peak power density which was 30% of the maximum peak power density (52.5 kW/m).

  18. Experiment data report for semiscale Mod-1 test S-06-4 (LOFT counterpart test)

    Energy Technology Data Exchange (ETDEWEB)

    Gillins, R. L.; Sackett, K. E.; Coppin, C. E.

    1977-12-01

    Recorded test data are presented for Test S-06-4 of the Semiscale Mod-1 LOFT counterpart test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-06-4 was conducted from initial conditions of 15,653 kPa and 564 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact loop to simulate emergency core coolant injection in a PWR. The heater rods in the electrically heated core were operated at an axial peak power density which was 100 percent of the maximum peak power density (52.5 kW/m).

  19. Spatial integration by a dielectric slab and its planar graphene-based counterpart.

    Science.gov (United States)

    Zangeneh-Nejad, Farzad; Khavasi, Amin

    2017-05-15

    In this contribution a new approach to perform spatial integration is presented using a dielectric slab. Our approach is indeed based on the fact that the transmission coefficient of a simple dielectric slab at its mode excitation angle matches the Fourier-Green's function of first-order integration. Inspired by the mentioned dielectric-based integrator, we further demonstrate its graphene-based counterpart. The latter is not only reconfigurable but also highly miniaturized in contrast to the previously reported designs [Opt. Commun.338, 457 (2015)OPCOB80030-401810.1016/j.optcom.2014.11.007]. Such integrators have the potential to be used in ultrafast analog computation and signal processing.

  20. Chitosan nanoparticles and their Tween 80 modified counterparts disrupt the developmental profile of zebrafish embryos.

    Science.gov (United States)

    Yuan, Zhongyue; Li, Ying; Hu, Yulan; You, Jian; Higashisaka, Kazuma; Nagano, Kazuya; Tsutsumi, Yasuo; Gao, Jianqing

    2016-12-30

    Chitosan nanoparticles (CS-NPs) and their Tween 80 modified counterparts (TmCS-NPs) are among the most commonly used brain-targeted vehicles. However, their potential developmental toxicity is poorly understood. In this study, zebrafish embryos are introduced as an in vivo platform. Both NPs showed a dose-dependent increase in developmental toxicity (decreased hatching rate, increased mortality and incidences of malformation). Neurobehavioral changes included decreased spontaneous movement in TmCS-NP treated embryos and hyperactive effect in CS-NP treated larvae. Both NPs remarkably inhibited axonal development of primary and secondary motor neurons, and affected the muscle structure. Overall, this study demonstrated that CS-NPs and TmCS-NPs could affect embryonic development, disrupt neurobehavior of zebrafish larvae and affect muscle and neuron development, suggesting more attention on biodegradable chitosan nanoparticles. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Comparison of occupational hearing losses among military engineers and their civilian counterparts.

    Science.gov (United States)

    Fletcher, J L; Chandler, D W

    1983-10-01

    A previous study (Chandler and Fletcher, J. Aud. Res., 1983, 23, 23-32) examined group hearing loss of 209 U.S. Army engineers by comparing current with reference audiograms. The sample was categorized by military occupation specialty, age, and time on job. The present study reports comparable data for 187 civilian engineers on the same Army post exposed to essentially the same noise. These had less hearing loss than their military counterparts. Some reasons are suggested, such as attrition of the civilian workforce because of hearing problems, and a likely greater exposure of the military engineers to noises not job-related. Age was less important than time on the job. Both groups, however, exhibited significantly lower hearing levels than the industrial population of Glorig et al (Am. Acad. Ophthalmol. Otolaryngol., 1957) at the 1954 Wisconsin State Fair, possibly because both military and civilian personnel at this Army post had been for some years in an aggressive hearing conservation program.

  2. CONSTRUCTIVISM AND REFLECTIVISM AS THE LOGICAL COUNTERPARTS IN TESOL: LEARNING THEORY VERSUS TEACHING METHODOLOGY

    Directory of Open Access Journals (Sweden)

    Abdullah al Mahmud

    2013-07-01

    Full Text Available The gist of the entire constructivist learning theory is that learners are self-builders of their learning that occurs through a mental process in a social context or communication setting, and teachers as facilitators generate learning by creating the expected environment and/or utilizing the process. This article theoretically proves reflectivism as the logical counterpart of constructivism through establishing their complete interdependence andthen suggests certain strategies of reflection to be used in language teaching for ensuring the best possible constructivist learning of language learners. In doing so, the basic tenets of constructivism and reflective thoughts are elaborated, examining their mutual connection thoroughly in terms of constructivist recommendations. The research also focuses on three case studies to depict how the theory of constructivist learning principles comes into practice through judicious reviews or reflective process.

  3. Analysis of counterpart tests performed in boiling water reactor experimental simulators

    Energy Technology Data Exchange (ETDEWEB)

    Bovalini, R.; D' Auria, F.; De Varti, A.; Maugeri, P.; Mazzini, M. (Univ. degli Studi di Pisa, Dept. di Construzioni Meccaniche e Nucleari, Via Diotisalvi 2, 56100 Pisa (IT))

    1992-01-01

    In this paper the main results obtained at the University of Pisa on small-break loss-of-coolant accident counterpart experiments carried out in boiling water reactor (BWR) experimental simulators are summarized. In particular, the results of similar experiments performed in the PIPER-ONE, Full Integral Simulation Test (FIST), and ROSA-III facilities are analyzed. The tests simulate a transient originated by a small break in the recirculation line of a BWR-6 with the high-pressure injection systems unavailable. RELAPS/MOD2 nodalizations have been set up for these facilities and for the reference BWR plant. The calculated results are compared among each other and with the experimental data. Finally, the merits and the limitations of such a program are discussed in view of the evaluation of code scaling capabilities and uncertainty.

  4. Nonrelativistic counterparts of twistors and the realizations of Galilean conformal algebra

    Energy Technology Data Exchange (ETDEWEB)

    Fedoruk, S., E-mail: fedoruk@theor.jinr.r [Bogoliubov Laboratory of Theoretical Physics, JINR, 141980 Dubna, Moscow region (Russian Federation); Kosinski, P., E-mail: pkosinsk@uni.lodz.p [Department of Theoretical Physics II, University of Lodz, Pomorska 149/153, 90-236 Lodz (Poland); Lukierski, J., E-mail: lukier@ift.uni.wroc.p [Institute for Theoretical Physics, University of Wroclaw, pl. Maxa Borna 9, 50-204 Wroclaw (Poland); Maslanka, P., E-mail: pmaslan@uni.lodz.p [Department of Theoretical Physics II, University of Lodz, Pomorska 149/153, 90-236 Lodz (Poland)

    2011-05-02

    Using the notion of Galilean conformal algebra (GCA) in arbitrary space dimension d, we introduce for d=3 quantized nonrelativistic counterpart of twistors as the spinorial representation of SO(2,1)+SO(3) which is the maximal semisimple subalgebra of three-dimensional GCA. The GC-covariant quantization of such nonrelativistic spinors, which shall be called also Galilean twistors, is presented. We consider for d=3 the general spinorial matrix realizations of GCA, which are further promoted to quantum-mechanical operator representations, expressed as bilinears in quantized Galilean twistors components. For arbitrary Hermitian quantum-mechanical Galilean twistor realizations we obtain the result that the representations of GCA with positive-definite Hamiltonian do not exist. For non-positive H we construct for N{>=}2 the Hermitian Galilean N-twistor realizations of GCA; for N=2 such realization is provided explicitly.

  5. Strategic Wholesale Pricing for an Incumbent Supplier Facing with a Competitive Counterpart

    Directory of Open Access Journals (Sweden)

    Jianwu Sun

    2014-01-01

    Full Text Available We introduce a wholesale pricing strategy for an incumbent supplier facing with a competitive counterpart. We propose a profit function which considers both the present loss and future loss from a wholesale price and then study the optimal wholesale prices for different objectives about this profit function for the incumbent supplier. First, we achieve an optimal wholesale price for the incumbent supplier to maximize his expected profit. Then, to reduce the risk originating from the fluctuation in the competitive supplier’s wholesale price, we integrate the conditional value-at-risk (CVaR measure in financial risk management into this study and derive an optimal wholesale price to maximize CVaR about profit for the incumbent supplier. Besides, the properties of the two optimal wholesale prices are discussed. Finally, some management insights are suggested for the incumbent supplier in a competitive setting.

  6. Strategic wholesale pricing for an incumbent supplier facing with a competitive counterpart.

    Science.gov (United States)

    Sun, Jianwu

    2014-01-01

    We introduce a wholesale pricing strategy for an incumbent supplier facing with a competitive counterpart. We propose a profit function which considers both the present loss and future loss from a wholesale price and then study the optimal wholesale prices for different objectives about this profit function for the incumbent supplier. First, we achieve an optimal wholesale price for the incumbent supplier to maximize his expected profit. Then, to reduce the risk originating from the fluctuation in the competitive supplier's wholesale price, we integrate the conditional value-at-risk (CVaR) measure in financial risk management into this study and derive an optimal wholesale price to maximize CVaR about profit for the incumbent supplier. Besides, the properties of the two optimal wholesale prices are discussed. Finally, some management insights are suggested for the incumbent supplier in a competitive setting.

  7. A Search for Optical Counterparts of Chandra Sources in Omega Centauri using ACS

    Science.gov (United States)

    Haggard, D.; Fuller, A. D.; Dorfman, J. L.; Cool, A. M.; Anderson, J.; Edmonds, P. D.; Davies, M. B.

    2002-12-01

    The globular cluster Omega Centauri, with its high mass and large, moderate density core, is of interest both for its population of primordial binaries and for the large number of tidal-capture and/or exchange-collision binaries it may harbor. We have obtained a 3x3 mosaic of Wide Field Camera pointings with HST's Advanced Camera for Surveys, covering a 10'x10' field out to the cluster's half-mass radius. Containing ~1.7 million detected stars, the resulting mosaic represents the most complete image of Omega Cen yet obtained. Here we report preliminary findings of a search in these data for optical counterparts to more than 100 faint X-ray sources (Lx ~ 2 x 1030 - 5 x 1032 erg-s-1) detected in our prior study of Omega Cen using the Chandra X-ray Observatory. Cluster X-ray sources are likely to consist primarily of accreting binary stars and close detached binaries with active coronae. Significant numbers of active galaxies in the background are also expected to be present. Using B, R, and H-alpha images, we are searching for optical counterparts that are H-alpha-bright and blue, as signatures of accretion in cataclysmic variables and/or quiescent low-mass X-ray binaries. Active binaries (e.g., BY Draconis stars) may appear as weaker H-alpha emitters lying on or slightly redward of the main sequence. This work is supported by NASA grant GO-9442 from the Space Telescope Science Institute.

  8. Subaru Hyper Suprime-Cam Survey for an optical counterpart of GW170817

    Science.gov (United States)

    Tominaga, Nozomu; Tanaka, Masaomi; Morokuma, Tomoki; Utsumi, Yousuke; Yamaguchi, Masaki S.; Yasuda, Naoki; Tanaka, Masayuki; Yoshida, Michitoshi; Fujiyoshi, Takuya; Furusawa, Hisanori; Kawabata, Koji S.; Lee, Chien-Hsiu; Motohara, Kentaro; Ohsawa, Ryou; Ohta, Kouji; Terai, Tsuyoshi; Abe, Fumio; Aoki, Wako; Asakura, Yuichiro; Barway, Sudhanshu; Bond, Ian A.; Fujisawa, Kenta; Honda, Satoshi; Ioka, Kunihito; Itoh, Youichi; Kawai, Nobuyuki; Kim, Ji Hoon; Koshimoto, Naoki; Matsubayashi, Kazuya; Miyazaki, Shota; Saito, Tomoki; Sekiguchi, Yuichiro; Sumi, Takahiro; Tristram, Paul J.

    2018-03-01

    We perform a z-band survey for an optical counterpart of the binary neutron star coalescence GW170817 with Subaru/Hyper Suprime-Cam. Our untargeted transient search covers 23.6 deg2 corresponding to the 56.6% credible region of GW170817 and reaches the 50% completeness magnitude of 20.6 mag on average. As a result, we find 60 candidate extragalactic transients, including J-GEM17btc (also known as SSS17a/DLT17ck). While J-GEM17btc is associated with NGC 4993, which is firmly located inside the 3D skymap of GW170817, the other 59 candidates do not have distance information in the GLADE v2 catalog or NASA/IPAC Extragalactic Database. Among 59 of the candidates, 58 are located at the center of extended objects in the Pan-STARRS1 catalog, while one candidate has an offset. We present location, z-band apparent magnitude, and time variability of the candidates and evaluate the probabilities that they are located within the 3D skymap of GW170817. The probability for J-GEM17btc is 64%, which is much higher than for the other 59 candidates (9.3 × 10-3-2.1 × 10-1%). Furthermore, the possibility that at least one of the other 59 candidates is located within the 3D skymap is only 3.2%. Therefore, we conclude that J-GEM17btc is the most likely and distinguished candidate to be the optical counterpart of GW170817.

  9. Subaru Hyper Suprime-Cam Survey for an optical counterpart of GW170817‡

    Science.gov (United States)

    Tominaga, Nozomu; Tanaka, Masaomi; Morokuma, Tomoki; Utsumi, Yousuke; Yamaguchi, Masaki S.; Yasuda, Naoki; Tanaka, Masayuki; Yoshida, Michitoshi; Fujiyoshi, Takuya; Furusawa, Hisanori; Kawabata, Koji S.; Lee, Chien-Hsiu; Motohara, Kentaro; Ohsawa, Ryou; Ohta, Kouji; Terai, Tsuyoshi; Abe, Fumio; Aoki, Wako; Asakura, Yuichiro; Barway, Sudhanshu; Bond, Ian A.; Fujisawa, Kenta; Honda, Satoshi; Ioka, Kunihito; Itoh, Youichi; Kawai, Nobuyuki; Kim, Ji Hoon; Koshimoto, Naoki; Matsubayashi, Kazuya; Miyazaki, Shota; Saito, Tomoki; Sekiguchi, Yuichiro; Sumi, Takahiro; Tristram, Paul J.

    2018-02-01

    We perform a z-band survey for an optical counterpart of the binary neutron star coalescence GW170817 with Subaru/Hyper Suprime-Cam. Our untargeted transient search covers 23.6 deg2 corresponding to the 56.6% credible region of GW170817 and reaches the 50% completeness magnitude of 20.6 mag on average. As a result, we find 60 candidate extragalactic transients, including J-GEM17btc (also known as SSS17a/DLT17ck). While J-GEM17btc is associated with NGC 4993, which is firmly located inside the 3D skymap of GW170817, the other 59 candidates do not have distance information in the GLADE v2 catalog or NASA/IPAC Extragalactic Database. Among 59 of the candidates, 58 are located at the center of extended objects in the Pan-STARRS1 catalog, while one candidate has an offset. We present location, z-band apparent magnitude, and time variability of the candidates and evaluate the probabilities that they are located within the 3D skymap of GW170817. The probability for J-GEM17btc is 64%, which is much higher than for the other 59 candidates (9.3 × 10-3-2.1 × 10-1%). Furthermore, the possibility that at least one of the other 59 candidates is located within the 3D skymap is only 3.2%. Therefore, we conclude that J-GEM17btc is the most likely and distinguished candidate to be the optical counterpart of GW170817.

  10. Study on the deterioration mechanism of layered rock-salt electrodes using epitaxial thin films - Li(Ni, Co, Mn)O2 and their Zr-O surface modified electrodes

    Science.gov (United States)

    Abe, Machiko; Iba, Hideaki; Suzuki, Kota; Minamishima, Hiroaki; Hirayama, Masaaki; Tamura, Kazuhisa; Mizuki, Jun'ichiro; Saito, Tomohiro; Ikuhara, Yuichi; Kanno, Ryoji

    2017-03-01

    Deterioration mechanism of Li(Ni, Co, Mn)O2 and Zr-O surface modified electrodes has been elucidated using epitaxial thin films synthesized by pulsed laser deposition. The electrodes comprise a mixture of layered rock-salt and spinel phases. The deterioration mechanism is analyzed using cyclic voltammetry, in situ X-ray diffraction measurements, and in situ neutron reflectometry. The spinel phase in the electrodes has low electrochemical activity and is not involved in Li insertion/extraction. The amount of Li participating in the charge-discharge reactions in the layered rock-salt phase increases with cycling, inducing a phase change at the electrode surface, lowering the reversibility. In contrast, in the Zr-O surface modified electrode, the spinel phase does not increase on charging/discharging. Thus, the Zr-O modification stabilizes the surface of layered rock-salt structure, thereby improving the cycling characteristics. Also, after the Zr-O modification, the Li concentration in the liquid electrolyte near the electrode/electrolyte interface increases during charging/discharging. The Zr-O surface modification not only stabilizes the electrode surface but also causes changes on the electrolyte side. Using the mixed model electrodes, we elucidate the mechanism of electrode deterioration and the origin of the improvement in cycling characteristics occurring on surface modification.

  11. A COMPREHENSIVE STUDY OF DETECTABILITY AND CONTAMINATION IN DEEP RAPID OPTICAL SEARCHES FOR GRAVITATIONAL WAVE COUNTERPARTS

    Energy Technology Data Exchange (ETDEWEB)

    Cowperthwaite, P. S.; Berger, E., E-mail: pcowpert@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States)

    2015-11-20

    The first direct detection of gravitational waves (GWs) by the ground-based Advanced LIGO/Virgo interferometers is expected to occur within the next few years. These interferometers are designed to detect the mergers of compact object binaries composed of neutron stars and/or black holes to a fiducial distance of ∼200 Mpc and a localization region of ∼100 deg{sup 2}. To maximize the science gains from such GW detections it is essential to identify electromagnetic counterparts. Among the wide range of proposed counterparts, the most promising is optical/IR emission powered by the radioactive decay of r-process elements synthesized in the neutron-rich merger ejecta—a “kilonova.” Here we present detailed simulated observations that encompass a range of strategies for kilonova searches during GW follow-up. We utilize these simulations to assess both the detectability of kilonovae and our ability to distinguish them from a wide range of contaminating transients in the large GW localization regions. We find that if pre-existing deep template images for the GW localization region are available, then nightly observations to a depth of i ≈ 24 mag and z ≈ 23 mag are required to achieve a 95% detection rate; observations that commence within ∼12 hr of trigger will also capture the kilonova peak and provide stronger constraints on the ejecta properties. We also find that kilonovae can be robustly separated from other known and hypothetical types of transients utilizing cuts on color (i − z ≳ 0.3 mag) and rise time (t{sub rise} ≲ 4 days). In the absence of a pre-existing template the observations must reach ∼1 mag deeper to achieve the same kilonova detection rate, but robust rejection of contaminants can still be achieved. Motivated by the results of our simulations we discuss the expected performance of current and future wide-field telescopes in achieving these observational goals, and find that prior to LSST the Dark Energy Camera on the Blanco 4 m

  12. XPS, XRD and laser Raman analysis of surface modified of 6150 steel substrates for the deposition of thick and adherent diamond-like carbon coatings

    Energy Technology Data Exchange (ETDEWEB)

    Silva, William de Melo; Carneiro, Jose Rubens Goncalves, E-mail: williammelosilva@gmail.com [Pontificia Universidade Catolica de Minas Gerais (PUC-MG), Belo Horizonte (Brazil). Dept. de Engenharia Mecanica; Trava-Airoldi, Vladimir Jesus [Associate Laboratory of Sensors and Materials, National Institute for Space Research, Sao Jose dos Campos, SP (Brazil)

    2013-11-01

    Although the 6150 steel has an excellent fatigue and impact resistance, it is unsuitable to operate it when the corrosion is a limited factor. We propose here a sequence of steel pre-treatment by carburizing, carbonitriding and nitriding in order to improve the poor adhesion between Diamond Like-Carbon coatings on steel. This sequence is our attempt to reduce the difference between the coefficients of thermal expansion of steel and DLC through the graded interface. This work demonstrates the quantitative analysis of the molecules present at surface using X-ray photoelectron spectroscopy. The crystallographic structures are investigated by X-ray diffraction which shows the formation of carbides and nitride phases. Raman spectroscopy reveals the carburizing surface characteristics where DLC coating is nucleated and grown at the substrate. At the end of the analysis it is possible to verify which molecules and phases are formed on the steel surface interface after each step of pre-treatment. (author)

  13. XPS, XRD and laser raman analysis of surface modified of 6150 steel substrates for the deposition of thick and adherent diamond-like carbon coatings

    Directory of Open Access Journals (Sweden)

    William de Melo Silva

    2013-06-01

    Full Text Available Although the 6150 steel has an excellent fatigue and impact resistance, it is unsuitable to operate it when the corrosion is a limited factor. We propose here a sequence of steel pre-treatment by carburizing, carbonitriding and nitriding in order to improve the poor adhesion between Diamond Like-Carbon coatings on steel. This sequence is our attempt to reduce the difference between the coefficients of thermal expansion of steel and DLC through the graded interface. This work demonstrates the quantitative analysis of the molecules present at surface using X-ray photoelectron spectroscopy. The crystallographic structures are investigated by X-ray diffraction which shows the formation of carbides and nitride phases. Raman spectroscopy reveals the carburizing surface characteristics where DLC coating is nucleated and grown at the substrate. At the end of the analysis it is possible to verify which molecules and phases are formed on the steel surface interface after each step of pre-treatment.

  14. Biomimetic Multispiked Connecting Ti-Alloy Scaffold Prototype for Entirely-Cementless Resurfacing Arthroplasty Endoprostheses—Exemplary Results of Implantation of the Ca-P Surface-Modified Scaffold Prototypes in Animal Model and Osteoblast Culture Evaluation

    Directory of Open Access Journals (Sweden)

    Ryszard Uklejewski

    2016-06-01

    Full Text Available We present here—designed, manufactured, and tested by our research team—the Ti-alloy prototype of the multispiked connecting scaffold (MSC-Scaffold interfacing the components of resurfacing arthroplasty (RA endoprostheses with bone. The spikes of the MSC-Scaffold prototype mimic the interdigitations of the articular subchondral bone, which is the natural biostructure interfacing the articular cartilage with the periarticular trabecular bone. To enhance the osteoinduction/osteointegration potential of the MSC-Scaffold, the attempts to modify its bone contacting surfaces by the process of electrochemical cathodic deposition of Ca-P was performed with further immersion of the MSC-Scaffold prototypes in SBF in order to transform the amorphous calcium-phosphate coating in hydroxyapatite-like (HA-like coating. The pilot experimental study of biointegration of unmodified and Ca-P surface-modified MSC-Scaffold prototypes was conducted in an animal model (swine and in osteoblast cell culture. On the basis of a microscope-histological method the biointegration was proven by the presence of trabeculae in the interspike spaces of the MSC-Scaffold prototype on longitudinal and cross-sections of bone-implant specimens. The percentage of trabeculae in the area between the spikes of specimen containing Ca-P surface modified scaffold prototype observed in microCT reconstructions of the explanted joints was visibly higher than in the case of unmodified MSC-Scaffold prototypes. Significantly higher Alkaline Phosphatase (ALP activity and the cellular proliferation in the case of Ca-P-modified MSC-Scaffold pre-prototypes, in comparison with unmodified pre-prototypes, was found in osteoblast cell cultures. The obtained results of experimental implantation in an animal model and osteoblast cell culture evaluations of Ca-P surface-modified and non-modified biomimetic MSC-Scaffold prototypes for biomimetic entirely-cementless RA endoprostheses indicate the

  15. Biomimetic Multispiked Connecting Ti-Alloy Scaffold Prototype for Entirely-Cementless Resurfacing Arthroplasty Endoprostheses-Exemplary Results of Implantation of the Ca-P Surface-Modified Scaffold Prototypes in Animal Model and Osteoblast Culture Evaluation.

    Science.gov (United States)

    Uklejewski, Ryszard; Rogala, Piotr; Winiecki, Mariusz; Tokłowicz, Renata; Ruszkowski, Piotr; Wołuń-Cholewa, Maria

    2016-06-29

    We present here-designed, manufactured, and tested by our research team-the Ti-alloy prototype of the multispiked connecting scaffold (MSC-Scaffold) interfacing the components of resurfacing arthroplasty (RA) endoprostheses with bone. The spikes of the MSC-Scaffold prototype mimic the interdigitations of the articular subchondral bone, which is the natural biostructure interfacing the articular cartilage with the periarticular trabecular bone. To enhance the osteoinduction/osteointegration potential of the MSC-Scaffold, the attempts to modify its bone contacting surfaces by the process of electrochemical cathodic deposition of Ca-P was performed with further immersion of the MSC-Scaffold prototypes in SBF in order to transform the amorphous calcium-phosphate coating in hydroxyapatite-like (HA-like) coating. The pilot experimental study of biointegration of unmodified and Ca-P surface-modified MSC-Scaffold prototypes was conducted in an animal model (swine) and in osteoblast cell culture. On the basis of a microscope-histological method the biointegration was proven by the presence of trabeculae in the interspike spaces of the MSC-Scaffold prototype on longitudinal and cross-sections of bone-implant specimens. The percentage of trabeculae in the area between the spikes of specimen containing Ca-P surface modified scaffold prototype observed in microCT reconstructions of the explanted joints was visibly higher than in the case of unmodified MSC-Scaffold prototypes. Significantly higher Alkaline Phosphatase (ALP) activity and the cellular proliferation in the case of Ca-P-modified MSC-Scaffold pre-prototypes, in comparison with unmodified pre-prototypes, was found in osteoblast cell cultures. The obtained results of experimental implantation in an animal model and osteoblast cell culture evaluations of Ca-P surface-modified and non-modified biomimetic MSC-Scaffold prototypes for biomimetic entirely-cementless RA endoprostheses indicate the enhancement of the

  16. Biomimetic Multispiked Connecting Ti-Alloy Scaffold Prototype for Entirely-Cementless Resurfacing Arthroplasty Endoprostheses—Exemplary Results of Implantation of the Ca-P Surface-Modified Scaffold Prototypes in Animal Model and Osteoblast Culture Evaluation

    Science.gov (United States)

    Uklejewski, Ryszard; Rogala, Piotr; Winiecki, Mariusz; Tokłowicz, Renata; Ruszkowski, Piotr; Wołuń-Cholewa, Maria

    2016-01-01

    We present here—designed, manufactured, and tested by our research team—the Ti-alloy prototype of the multispiked connecting scaffold (MSC-Scaffold) interfacing the components of resurfacing arthroplasty (RA) endoprostheses with bone. The spikes of the MSC-Scaffold prototype mimic the interdigitations of the articular subchondral bone, which is the natural biostructure interfacing the articular cartilage with the periarticular trabecular bone. To enhance the osteoinduction/osteointegration potential of the MSC-Scaffold, the attempts to modify its bone contacting surfaces by the process of electrochemical cathodic deposition of Ca-P was performed with further immersion of the MSC-Scaffold prototypes in SBF in order to transform the amorphous calcium-phosphate coating in hydroxyapatite-like (HA-like) coating. The pilot experimental study of biointegration of unmodified and Ca-P surface-modified MSC-Scaffold prototypes was conducted in an animal model (swine) and in osteoblast cell culture. On the basis of a microscope-histological method the biointegration was proven by the presence of trabeculae in the interspike spaces of the MSC-Scaffold prototype on longitudinal and cross-sections of bone-implant specimens. The percentage of trabeculae in the area between the spikes of specimen containing Ca-P surface modified scaffold prototype observed in microCT reconstructions of the explanted joints was visibly higher than in the case of unmodified MSC-Scaffold prototypes. Significantly higher Alkaline Phosphatase (ALP) activity and the cellular proliferation in the case of Ca-P-modified MSC-Scaffold pre-prototypes, in comparison with unmodified pre-prototypes, was found in osteoblast cell cultures. The obtained results of experimental implantation in an animal model and osteoblast cell culture evaluations of Ca-P surface-modified and non-modified biomimetic MSC-Scaffold prototypes for biomimetic entirely-cementless RA endoprostheses indicate the enhancement of the

  17. Experiment data report for semiscale Mod-1 test S-06-6 (LOFT counterpart test). [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Esparza, V.; Sackett, K. E.

    1977-09-01

    Recorded test data are presented for Test S-06-6 of the Semiscale Mod-1 LOFT counterpart test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-06-6 was conducted from initial conditions of 15 792 kPa and 563 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact loop to simulate emergency core coolant injection in a PWR. The heater rods in the electrically heated core were operated at an axial peak power density which was 75% of the maximum peak power density (52.5 kW/m). Test S-06-6 also evaluated the effect of special hardware assumptions on the core response.

  18. Experiment data report for semiscale Mod-1 Test S-06-5. (LOFT counterpart test). [PWR

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-06-01

    Recorded test data are presented for Test S-06-5 of the Semiscale Mod-1 LOFT counterpart test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-06-5 was conducted from initial conditions of 2272 psia and 536/sup 0/F to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold legs of the intact and broken loops to simulate emergency core coolant injection in a PWR. The purpose of Test S-06-5 was to assess the influence of the break nozzle geometry on core thermal and system response and on the subcooled and low quality mass flow rates at the break locations.

  19. Moringa oleifera Root Induces Cancer Apoptosis more Effectively than Leave Nanocomposites and Its Free Counterpart

    Science.gov (United States)

    Abd-Rabou, Ahmed A; Abdalla, Aboelfetoh M; Ali, Naglaa A; Zoheir, Khairy MA

    2017-01-01

    Medicinal plants are important elements of indigenous medical system that have persisted in developing countries. Many of the botanical chemo-preventions currently used as potent anticancer agents. However, some important anticancer agents are still extracted from plants because they cannot be synthesized chemically on a commercial scale due to their complex structures that often contain several chiral centers. The aim of this study was to test different extracts from the Moringa oleifera leaves (ML), its PLGA-CS-PEG nanocomposites (MLn), as well as root core (Rc) and outer (Ro) parts for activity against hepatocarcinoma HepG2, breast MCF7, and colorectal HCT 116/ Caco-2 cells in vitro. Nano-composites were prepared and characterized. Then, the nanocomposites and the free counterparts were screened on different propagated cancer cell lines. The underlying cytotoxic impact was followed using apoptosis measurements. All extracts kill the different cancer cells with different ratios, but intriguingly, the root core extract could kill the majority of cancer cells (approximately 70-80%), while sparing normal BHK-21 cells with minimal inhibitory effect (approximately 30-40%). Apoptotic cell increment came to confirm the cytotoxic effects of these extracts on HCT 116 cells (Rc: 212% and Ro: 180%, respectively) and HepG2 cells (ML: 567.5% and MLn: 608%, respectively) compared to control (100%) mechanistically wise. Moringa oleifera nanocomposites may have potential for use as a natural source of anti-cancer compounds. PMID:28843248

  20. Elaboration of a guideline for counterpart testing of integral loop systems

    International Nuclear Information System (INIS)

    Karwat, H.

    1988-01-01

    A previous study on the problems of scaling and extrapolation of experimental results indicated the necessity to overcome some uncertainty in the achievable code accuracy when applied to full size reactor systems. The empirical approach in simulating interfacial relationships within systems behaviour codes in combination with the liberty of nodalisation requires a careful assessment of the overall validity of the code verification concept. Several new test facilities are presently under construction to study fluid-dynamic effects of interest for the behaviour of PWRs under small break LOCA conditions in a larger dimension and with somewhat modified scaling considerations. The test results expected from these new facilities may be useful to assess the overall validity of the analytical simulation concept of the applied computer codes. Test facilities of interest within the European Community are the - LOBI Test Facility (vol. scaling 1/700) at JRC-Ispra - SPES Test Facility (vol. scaling 1/425) in Italy - BETHSY Facility (vol scaling 1/100) in France and outside Europe the - ROSA IV Facility (vol. scaling 1/50) in Japan. Main objective of the study was the elaboration of a guideline for the particular requirements of meaningful counterpart testing with the final aim to qualify the overall validity of code simulation concepts and the expected predictive accuracy of code applications for full size prototype PWRs

  1. Combining Gravitational Wave Events with their Electromagnetic Counterparts: A Realistic Joint False-Alarm Rate

    Science.gov (United States)

    Ackley, Kendall; Eikenberry, Stephen; Klimenko, Sergey; LIGO Team

    2017-01-01

    We present a false-alarm rate for a joint detection of gravitational wave (GW) events and associated electromagnetic (EM) counterparts for Advanced LIGO and Virgo (LV) observations during the first years of operation. Using simulated GW events and their recostructed probability skymaps, we tile over the error regions using sets of archival wide-field telescope survey images and recover the number of astrophysical transients to be expected during LV-EM followup. With the known GW event injection coordinates we inject artificial electromagnetic (EM) sources at that site based on theoretical and observational models on a one-to-one basis. We calculate the EM false-alarm probability using an unsupervised machine learning algorithm based on shapelet analysis which has shown to be a strong discriminator between astrophysical transients and image artifacts while reducing the set of transients to be manually vetted by five orders of magnitude. We also show the performance of our method in context with other machine-learned transient classification and reduction algorithms, showing comparability without the need for a large set of training data opening the possibility for next-generation telescopes to take advantage of this pipeline for LV-EM followup missions.

  2. BurstCube: A CubeSat for Gravitational Wave Counterparts

    Science.gov (United States)

    Perkins, Jeremy S.; Racusin, Judith; Briggs, Michael; de Nolfo, Georgia; Caputo, Regina; Krizmanic, John; McEnery, Julie E.; Shawhan, Peter; Morris, David; Connaughton, Valerie; Kocevski, Dan; Wilson-Hodge, Colleen A.; Hui, Michelle; Mitchell, Lee; McBreen, Sheila

    2018-01-01

    We present BurstCube, a novel CubeSat that will detect and localize Gamma-ray Bursts (GRBs). BurstCube is a selected mission that will detect long GRBs, attributed to the collapse of massive stars, short GRBs (sGRBs), resulting from binary neutron star mergers, as well as other gamma-ray transients in the energy range 10-1000 keV. sGRBs are of particular interest because they are predicted to be the counterparts of gravitational wave (GW) sources soon to be detectable by LIGO/Virgo. BurstCube contains 4 CsI scintillators coupled with arrays of compact low-power Silicon photomultipliers (SiPMs) on a 6U Dellingr bus, a flagship modular platform that is easily modifiable for a variety of 6U CubeSat architectures. BurstCube will complement existing facilities such as Swift and Fermi in the short term, and provide a means for GRB detection, localization, and characterization in the interim time before the next generation future gamma-ray mission flies, as well as space-qualify SiPMs and test technologies for future use on larger gamma-ray missions. The ultimate configuration of BurstCube is to have a set of ~10 BurstCubes to provide all-sky coverage to GRBs for substantially lower cost than a full-scale mission.

  3. Do Asian women do as well as their Caucasian counterparts in IVF treatment: Cohort study.

    Science.gov (United States)

    Kan, Andrew; Leung, Peter; Luo, Kehui; Fay, Louise; Tan, Chunyan Leeann

    2015-06-01

    To evaluate if there is a difference in pregnancy rate between Asian and Caucasian women when they undergo in vitro fertilization (IVF). This was a retrospective cohort study set in a private reproductive medicine clinic. The study consisted of a total of 2594 patients (Asian, n = 522; Caucasian, n = 2072) undergoing IVF managed by a single doctor over a 10 year period. The main outcome measures were clinical pregnancy rate and live birth rate. Logistic regression was used to control for confounding factors. Asian women achieved a significantly lower clinical pregnancy and live birth rate than their Caucasian counterparts, despite replacement of more embryos. This difference was not significant after controlling for age and duration of infertility. Despite higher doses of gonadotrophin, they achieved fewer oocytes and had resultant fewer embryos for transfer or cryopreservation. In a study designed to reduce the effect of confounding factors by looking at a large number of patients from a single IVF unit under the care of a single doctor, there does not appear to be a difference in IVF pregnancy rate as a result of race. Asian women tend to present for IVF treatment at a later age after having tried for a longer period of time and this contributes significantly to their lower pregnancy rate. © 2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology.

  4. X-ray counterpart candidates for six new γ-ray pulsars

    Science.gov (United States)

    Zyuzin, Dmitry A.; Karpova, Anna V.; Shibanov, Yuriy A.

    2018-05-01

    Using archival X-ray data, we have found point-like X-ray counterpart candidates positionally coincident with six γ-ray pulsars discovered recently in the Fermi Gamma-ray Space Telescope data by the Einstein@Home project. The candidates for PSRs J0002+6216, J0554+3107, J1844-0346, and J1105-6037 are detected with Swift, and those for PSRs J0359+5414 and J2017+3625 are detected with Chandra. Despite a low count statistics for some candidates, assuming plausible constraints on the absorbing column density towards the pulsars, we show that X-ray spectral properties for all of them are consistent with those observed for other pulsars. J0359+5414 is the most reliably identified object. We detect a nebula around it, whose spectrum and extent suggest that this is a pulsar wind nebula powered by the pulsar. Associations of J0002+6216 and J1844-0346 with supernova remnants CTB 1 and G28.6-0.1 are proposed.

  5. J-GEM observations of an electromagnetic counterpart to the neutron star merger GW170817

    Science.gov (United States)

    Utsumi, Yousuke; Tanaka, Masaomi; Tominaga, Nozomu; Yoshida, Michitoshi; Barway, Sudhanshu; Nagayama, Takahiro; Zenko, Tetsuya; Aoki, Kentaro; Fujiyoshi, Takuya; Furusawa, Hisanori; Kawabata, Koji S.; Koshida, Shintaro; Lee, Chien-Hsiu; Morokuma, Tomoki; Motohara, Kentaro; Nakata, Fumiaki; Ohsawa, Ryou; Ohta, Kouji; Okita, Hirofumi; Tajitsu, Akito; Tanaka, Ichi; Terai, Tsuyoshi; Yasuda, Naoki; Abe, Fumio; Asakura, Yuichiro; Bond, Ian A.; Miyazaki, Shota; Sumi, Takahiro; Tristram, Paul J.; Honda, Satoshi; Itoh, Ryosuke; Itoh, Yoichi; Kawabata, Miho; Morihana, Kumiko; Nagashima, Hiroki; Nakaoka, Tatsuya; Ohshima, Tomohito; Takahashi, Jun; Takayama, Masaki; Aoki, Wako; Baar, Stefan; Doi, Mamoru; Finet, Francois; Kanda, Nobuyuki; Kawai, Nobuyuki; Kim, Ji Hoon; Kuroda, Daisuke; Liu, Wei; Matsubayashi, Kazuya; Murata, Katsuhiro L.; Nagai, Hiroshi; Saito, Tomoki; Saito, Yoshihiko; Sako, Shigeyuki; Sekiguchi, Yuichiro; Tamura, Yoichi; Tanaka, Masayuki; Uemura, Makoto; Yamaguchi, Masaki S.

    2017-12-01

    GW170817 is the first detected gravitational wave source from a neutron star merger. We present the Japanese collaboration for gravitational-wave electro-magnetic (J-GEM) follow-up observations of SSS17a, an electromagnetic counterpart of GW170817. SSS17a shows a 2.5 mag decline in the z band during the period between 1.7 and 7.7 d after the merger. Such a rapid decline is not comparable with supernovae light curves at any epoch. The color of SSS17a also evolves rapidly and becomes redder during later epochs: the z - H color has changed by approximately 2.5 mag during the period between 0.7 and 7.7 d. The rapid evolutions of both the color and the optical brightness are consistent with the expected properties of a kilonova that is powered by the radioactive decay of newly synthesized r-process nuclei. Kilonova models with Lanthanide elements can reproduce the aforementioned observed properties well, which suggests that r-process nucleosynthesis beyond the second peak takes place in SSS17a. However, the absolute magnitude of SSS17a is brighter than the expected brightness of the kilonova models with an ejecta mass of 0.01 M⊙, which suggests a more intense mass ejection (˜0.03 M⊙) or possibly an additional energy source.

  6. Superatom spectroscopy and the electronic state correlation between elements and isoelectronic molecular counterparts.

    Science.gov (United States)

    Peppernick, Samuel J; Gunaratne, K D Dasitha; Castleman, A W

    2010-01-19

    Detailed in the present investigation are results pertaining to the photoelectron spectroscopy of negatively charged atomic ions and their isoelectronic molecular counterparts. Experiments utilizing the photoelectron imaging technique are performed on the negative ions of the group 10 noble metal block (i.e. Ni-, Pd-, and Pt-) of the periodic table at a photon energy of 2.33 eV (532 nm). The accessible electronic transitions, term energies, and orbital angular momentum components of the bound electronic states in the atom are then compared with photoelectron images collected for isoelectronic early transition metal heterogeneous diatomic molecules, M-X- (M = Ti,Zr,W; X = O or C). A superposition principle connecting the spectroscopy between the atomic and molecular species is observed, wherein the electronic structure of the diatomic is observed to mimic that present in the isoelectronic atom. The molecular ions studied in this work, TiO-, ZrO-, and WC- can then be interpreted as possessing superatomic electronic structures reminiscent of the isoelectronic elements appearing on the periodic table, thereby quantifying the superatom concept.

  7. Real-time Automatic Search for Multi-wavelength Counterparts of DWF Transients

    Science.gov (United States)

    Murphy, Christopher; Cucchiara, Antonino; Andreoni, Igor; Cooke, Jeff; Hegarty, Sarah

    2018-01-01

    The Deeper Wider Faster (DWF) survey aims to find and classify the fastest transients in the Universe. DWF utilizes the Dark Energy Camera (DECam), collecting a continuous sequence of 20s images over a 3 square degree field of view.Once an interesting transient is detected during DWF observations, the DWF collaboration has access to several facilities for rapid follow-up in multiple wavelengths (from gamma to radio).An online web tool has been designed to help with real-time visual classification of possible astrophysical transients in data collected by the DWF observing program. The goal of this project is to create a python-based code to improve the classification process by querying several existing archive databases. Given the DWF transient location and search radius, the developed code will extract a list of possible counterparts and all available information (e.g. magnitude, radio fluxes, distance separation).Thanks to this tool, the human classifier can make a quicker decision in order to trigger the collaboration rapid-response resources.

  8. Multiwavelength counterparts of the point sources in the Chandra Source Catalog

    Science.gov (United States)

    Reynolds, Michael; Civano, Francesca Maria; Fabbiano, Giuseppina; D'Abrusco, Raffaele

    2018-01-01

    The most recent release of the Chandra Source Catalog (CSC) version 2.0 comprises more than $\\sim$350,000 point sources, down to fluxes of $\\sim$10$^{-16}$ erg/cm$^2$/s, covering $\\sim$500 deg$^2$ of the sky, making it one of the best available X-ray catalogs to date. There are many reasons to have multiwavelength counterparts for sources, one such reason is that X-ray information alone is not enough to identify the sources and divide them between galactic and extragalactic origin, therefore multiwavelength data associated to each X-ray source is crucial for classification and scientific analysis of the sample. To perform this multiwavelength association, we are going to employ the recently released versatile tool NWAY (Salvato et al. 2017), based on a Bayesian algorithm for cross-matching multiple catalogs. NWAY allows the combination of multiple catalogs at the same time, provides a probability for the matches, even in case of non-detection due to different depth of the matching catalogs, and it can be used by including priors on the nature of the sources (e.g. colors, magnitudes, etc). In this poster, we are presenting the preliminary analysis using the CSC sources above the galactic plane matched to the WISE All-Sky catalog, SDSS, Pan-STARRS and GALEX.

  9. “The Scum of the Earth”? Foreign People Smugglers and Their Local Counterparts in Indonesia

    Directory of Open Access Journals (Sweden)

    Antje Missbach

    2011-01-01

    Full Text Available Since 2008, the number of asylum seekers and refugees trying to reach Australia from Indonesia by boat has increased. With many of them hailing from conflict-ridden countries such as Afghanistan, Iraq and Sri Lanka, most entered Indonesia with short-term tourist visas or fraudulent papers or no documents at all. It is widely known that a significant number of these ‘irregular’ migrants pay various types of brokers (often labelled, accurately or otherwise, ‘human smugglers’ at least at one stage – either to enter the country or to escape it. As a non-signatory to the UN Refugee Convention, Indonesia does not permit local integration. While a substantial part of these migrants are detained in the 13 immigration detention centres scattered around the archipelago, many roam freely, looking for opportunities for onward migration. Due to the restrictive border protection arrangements between Australia and Indonesia and a number of bilateral intelligence measures for deterring ‘unwanted’ migrants, human smugglers have been gradually forced to adapt strategies, routes and prices. According to much of the available data, most human smugglers are not Indonesians but foreigners who have been lingering in Indonesia for many years. This article demonstrates, moreover, that these foreigners depend upon local contacts to successfully carry out their risky business. Most often, the Indonesian counterparts are solely facilitators or handymen, but in a number of cases Indonesian authorities have also been involved in this highly lucrative business.

  10. Holocene reef associated carbonate sediments and their Pleistocene counterparts, Miyako Islands, Ryukyus, southwest of Japan

    Energy Technology Data Exchange (ETDEWEB)

    Tsuji, Y.; Yamamura, T.; Kodato, T.; Sunouchi, H.

    1988-01-01

    Holocene carbonate sedimentary facies distribution, from sea level to shelf slope about 1,000 m in depth, and its relationship to bathymeltry, off Miyako Island, Ryukyus, southwest of Japan were clarified by surveys with sidescan sonar, sparker, uniboom, sea-bottom camera, and sediment sampler. Six facies were recognized using the acoustic data, sample analytical data, and sea-bottom photographs. These are as follows: (A) Reef facies: made mainly of autochthonous hermatypic corals and encrusting algae, 0-60 m deep. (B) Inter-reef muddy facies: consists of very fine sand-size carbonate fraction and line mud, 20-60 m deep surrounded area be reefal relief and islands. (C) Inter-reef and near-reef sandy facies: characterized by tests of shallow benthic foraminifera Calcarina and Marginopora, and Halimeda fragments, 0-90 m deep. (D) Rhodolith and large foraminiferal gravelly shelf facies: contains pebble to cobble-size rhodolith and/and foraminifera Cycloclypeus and Operculina, 60-200 m deep. (E) Bryozoan sandy shelf facies: rich in byrozoan fragments, 80-200 m deep. (F) Shelf slope pelagic foraminiferal facies: dominated by pelagic foraminifera and pteropod molluscan tests, deeper than 200 m. Counterparts of these facies in emerged Pleistocene limestone sequences have been recognized in outcrops and core samples. The results of the marine survey on Holocene deposits made it easy to interpret the Pleistocene depositional environments and sea level changes.

  11. The cocoon emission - an electromagnetic counterpart to gravitational waves from neutron star mergers

    Science.gov (United States)

    Gottlieb, Ore; Nakar, Ehud; Piran, Tsvi

    2018-01-01

    Short gamma-ray bursts are believed to arise from compact binary mergers (either neutron star-neutron star or black hole-neutron star). If so, their jets must penetrate outflows that are ejected during the merger. As a jet crosses the ejecta, it dissipates its energy, producing a hot cocoon that surrounds it. We present here 3D numerical simulations of jet propagation in mergers' outflows, and we calculate the resulting emission. This emission consists of two components: the cooling emission, the leakage of the thermal energy of the hot cocoon, and the cocoon macronova that arises from the radioactive decay of the cocoon's material. This emission gives a brief (∼1 h) blue, wide angle signal. While the parameters of the outflow and jet are uncertain, for the configurations we have considered, the signal is bright (∼-14 to -15 absolute magnitude) and outshines all other predicted ultraviolet-optical signals. The signal is brighter when the jet breakout time is longer, and its peak brightness does not depend strongly on the highly uncertain opacity. A rapid search for such a signal is a promising strategy to detect an electromagnetic merger counterpart. A detected candidate could be then followed by deep infrared searches for the longer but weaker macronova arising from the rest of the ejecta.

  12. Identification of the Infrared Counterpart of SGR 1935+2154 with the Hubble Space Telescope

    Science.gov (United States)

    Levan, Andrew; Kouveliotou, Chryssa; Fruchter, Andrew

    2018-02-01

    We present deep Hubble Space Telescope observations of a new magnetar source, the soft gamma-repeater SGR 1935+2154, discovered by Swift. We obtained three epochs of observations: while the source was active in 2015 March, during a quiescent period in 2015 August, and during a further active phase in 2016 May. Close to the center of the X-ray error region identified by Chandra, we find a faint (F140W(AB) = 25.3) source, which fades by a factor of ∼2 over the course of 5 months between the first two epochs of observations, before rebrightening during the second active period. If this source is indeed the counterpart to SGR 1935+2154, then it is among the faintest yet located for a magnetar. Our observations are spaced over 1.3 years and enable us to place limits on the source velocity of μ = (60 ± 40) km s‑1 kpc‑1 observations on timescales of a decade can hence probe proper motion limits smaller than the velocities observed for the majority of pulsars. The comparison of the optical/IR and X-ray light curves of the source suggests that emission in the two regimes is associated but not directly correlated, offering support for a magnetospheric versus a fallback disk origin.

  13. KF post-deposition treatment of industrial Cu(In, Ga)(S, Se)2 thin-film surfaces: Modifying the chemical and electronic structure

    Science.gov (United States)

    Mezher, Michelle; Mansfield, Lorelle M.; Horsley, Kimberly; Blum, Monika; Wieting, Robert; Weinhardt, Lothar; Ramanathan, Kannan; Heske, Clemens

    2017-08-01

    The chemical and electronic structures of industrial chalcopyrite photovoltaic absorbers after KF post-deposition treatment (KF-PDT) are investigated using electron spectroscopies to probe the occupied and unoccupied electronic states. In contrast to a variety of recent publications on the impact of KF-PDT, this study focuses on industrial Cu(In,Ga)(S,Se)2 absorbers that also contain sulfur at the surface. We find that the KF-PDT removes surface adsorbates and oxides and also observe a change in the S/Se ratio. Furthermore, the KF-PDT leads to a Cu reduction at the surface but to a much lower degree than the strongly Cu-depleted or even Cu-free surfaces reported for (non-industrial) sulfur-free Cu(In,Ga)Se2 absorbers. The valence band maximum at the surface is found at a lower energy compared to the untreated absorber, and the conduction band minimum is found at a higher energy, overall revealing a widening of the bandgap in the surface region.

  14. Unravelling the potential of nitric acid as a surface modifier for improving the hemocompatibility of metallocene polyethylene for blood contacting devices

    Directory of Open Access Journals (Sweden)

    Muthu Vignesh Vellayappan

    2016-01-01

    Full Text Available Design of blood compatible surfaces is obligatory to minimize platelet surface interactions and improve the thromboresistance of foreign surfaces when they are utilized as biomaterials particularly for blood contacting devices. Pure metallocene polyethylene (mPE and nitric acid (HNO3 treated mPE antithrombogenicity and hydrophilicity were investigated. The contact angle of the mPE treated with HNO3 decreased. Surface of mPE and HNO3 treated mPE investigated with FTIR revealed no major changes in its functional groups. 3D Hirox digital microscopy, SEM and AFM images show increased porosity and surface roughness. Blood coagulation assays prothrombin time (PT and activated partial thromboplastin time (APTT were delayed significantly (P < 0.05 for HNO3 treated mPE. Hemolysis assay and platelet adhesion of the treated surface resulted in the lysis of red blood cells and platelet adherence, respectively indicating improved hemocompatibility of HNO3 treated mPE. To determine that HNO3 does not deteriorate elastic modulus of mPE, the elastic modulus of mPE and HNO3 treated mPE was compared and the result shows no significant difference. Hence, the overall observation suggests that the novel HNO3 treated mPE may hold great promises to be exploited for blood contacting devices like grafts, catheters, and etc.

  15. Unravelling the potential of nitric acid as a surface modifier for improving the hemocompatibility of metallocene polyethylene for blood contacting devices.

    Science.gov (United States)

    Vellayappan, Muthu Vignesh; Jaganathan, Saravana Kumar; Muhamad, Ida Idayu

    2016-01-01

    Design of blood compatible surfaces is obligatory to minimize platelet surface interactions and improve the thromboresistance of foreign surfaces when they are utilized as biomaterials particularly for blood contacting devices. Pure metallocene polyethylene (mPE) and nitric acid (HNO3) treated mPE antithrombogenicity and hydrophilicity were investigated. The contact angle of the mPE treated with HNO3 decreased. Surface of mPE and HNO3 treated mPE investigated with FTIR revealed no major changes in its functional groups. 3D Hirox digital microscopy, SEM and AFM images show increased porosity and surface roughness. Blood coagulation assays prothrombin time (PT) and activated partial thromboplastin time (APTT) were delayed significantly (P < 0.05) for HNO3 treated mPE. Hemolysis assay and platelet adhesion of the treated surface resulted in the lysis of red blood cells and platelet adherence, respectively indicating improved hemocompatibility of HNO3 treated mPE. To determine that HNO3 does not deteriorate elastic modulus of mPE, the elastic modulus of mPE and HNO3 treated mPE was compared and the result shows no significant difference. Hence, the overall observation suggests that the novel HNO3 treated mPE may hold great promises to be exploited for blood contacting devices like grafts, catheters, and etc.

  16. Tribological responses of the WC/a-C film to sliding against different counterparts in air, water and oil

    Science.gov (United States)

    Sun, Shangqi; Wang, Yongxin; Ye, Yuwei; Liu, Xiang; Lu, Xia; Li, Jinlong

    2017-10-01

    The WC/a-C film prepared using a reactive magnetron sputtering system was investigated. The film structure and properties were characterized, and the friction response mechanism between this film and several counterparts was investigated under different environments. The hardness and surface roughness of the counterpart as well as the match between the properties of the counterpart and the film were identified as factors that play a critical role in the friction behaviour. The environment affected the extent of wear through physical and chemical reactions, and mechanical wear with friction chemical reactions was found to be the major mechanism of influence. This study is of great practical interest, as it will help to extend the service life of WC/a-C films and minimize loss during the initial running-in period.

  17. Search for High-Confidence Blazar Candidates and Their MWL Counterparts in the Fermi-LAT Catalog Using Machine Learning

    Directory of Open Access Journals (Sweden)

    Sabrina Einecke

    2016-08-01

    Full Text Available A large fraction of the gamma-ray sources presented in the Third Fermi-LAT source catalog (3FGL is affiliated with counterparts and source types, but 1010 sources remain unassociated and 573 sources are associated with active galaxies of uncertain type. The purpose of this study is to assign blazar classes to these unassociated and uncertain sources, and to link counterparts to the unassociated. A machine learning algorithm is used for the classification, based on properties extracted from the 3FGL, an infrared and an X-ray catalog. To estimate the reliability of the classification, performance measures are considered through validation techniques. The classification yielded purity values around 90% with efficiency values of roughly 50%. The prediction of high-confidence blazar candidates has been conducted successfully, and the possibility to link counterparts in the same procedure has been proven. These findings confirm the relevance of this novel multiwavelength approach.

  18. Mathematics revealed

    CERN Document Server

    Berman, Elizabeth

    1979-01-01

    Mathematics Revealed focuses on the principles, processes, operations, and exercises in mathematics.The book first offers information on whole numbers, fractions, and decimals and percents. Discussions focus on measuring length, percent, decimals, numbers as products, addition and subtraction of fractions, mixed numbers and ratios, division of fractions, addition, subtraction, multiplication, and division. The text then examines positive and negative numbers and powers and computation. Topics include division and averages, multiplication, ratios, and measurements, scientific notation and estim

  19. Community Stroke Rehabilitation: How Do Rural Residents Fare Compared With Their Urban Counterparts?

    Science.gov (United States)

    Allen, Laura; McIntyre, Amanda; Janzen, Shannon; Richardson, Marina; Meyer, Matthew; Ure, David; Teasell, Robert

    2016-01-01

    Rural living has been demonstrated to have an effect on a person's overall health status, and rural residing individuals often have decreased access to health and specialized rehabilitation services. The aim of this study was to determine if there are differences in recovery from stroke between urban and rural-dwelling stroke survivors accessing an in-home, community-based, interdisciplinary, stroke rehabilitation program. Data from a cohort of 1222 stroke survivors receiving care from the Community Stroke Rehabilitation Teams between January 2009 and June 2013 was analyzed. This program delivers stroke rehabilitation care directly in a person's home and community. Functional and psychosocial outcomes were evaluated at baseline, discharge, and six -month follow-up. A series of multiple linear regression analyses was performed to determine if rural versus urban status was a significant predictor of discharge and 6-month health outcomes. The mean age of the rural cohort was 68.8 (±13.1) years (53.6% male), and the urban cohort was 68.4 (±13.0) years (44.8% male). A total of 278 (35.4%) individuals were classified as living in a rural area using the Rurality Index for Ontario. In multivariate linear regression analysis, no significant differences on the Functional Independence Measure, the Stroke Impact Scale, the Hospital Anxiety and Depression Scale, or the Reintegration to Normal Living Index were found between urban and rural cohorts. When provided with access to a home-based, specialized stroke rehabilitation program, rural dwelling stroke survivors make and maintain functional gains comparable to their urban-living counterparts.

  20. Optical Counterparts for Low-Luminosity X-ray Sources in Omega Centauri

    Science.gov (United States)

    Cool, Adrienne

    2002-07-01

    We propose to use narrow-band HAlpha imaging with ACS to search for the optical counterparts of low-luminosity X-ray sources {Lx 2 x 10^30 - 5 x 10^32 erg/s} in the globular cluster Omega Centauri. With 9 WFC fields, we will cover the inner two core radii of the cluster, and encompass about 90 of the faint sources we have identified with Chandra. Approximately 30-50 of these sources should be cluster members, the remainder being mostly background galaxies plus a smaller number of foreground stars. This large population of low-Lx cluster X-ray sources is second only to the more than 100 faint sources recently discovered in 47 Tuc with Chandra {Grindlay et al. 2001a}, which have been identified as a mixture of cataclysmic variables, quiescent low-mass X-ray binaries, millisecond pulsars, and coronally active main-sequence binaries. Our Cycle 6 WFPC2 program successfully identified 2 of the 3 then-known faint X-ray sources in the core of Omega Cen using H-alpha imaging. We now propose to expand the areal coverage by a factor of about 18 to encompass the much larger number of sources that have since been discovered with Chandra. The extreme crowding in the central regions of Omega Cen requires the resolution of HST to obtain optical IDs. These identifications are key to making meaningful comparisons between the populations of faint X-ray sources in different clusters, in an effort to understand their origins and role in cluster dynamics.

  1. Genomic variations in the counterpart normal controls of lung squamous cell carcinomas.

    Science.gov (United States)

    Qu, Liwei; Zhou, Bo; Wang, Guizhen; Zhou, Guangbiao

    2017-11-28

    Lung squamous cell carcinoma (LUSC) causes approximately 400 000 deaths each year worldwide. The occurrence of LUSC is attributed to exposure to cigarette smoke, which induces the development of numerous genomic abnormalities. However, few studies have investigated the genomic variations that occur only in normal tissues that have been similarly exposed to tobacco smoke as tumor tissues. In this study, we sequenced the whole genomes of three normal lung tissue samples and their paired adjacent squamous cell carcinomas.We then called genomic variations specific to the normal lung tissues through filtering the genomic sequence of the normal lung tissues against that of the paired tumors, the reference human genome, the dbSNP138 common germline variants, and the variations derived from sequencing artifacts. To expand these observations, the whole exome sequences of 478 counterpart normal controls (CNCs) and paired LUSCs of The Cancer Genome Atlas (TCGA) dataset were analyzed. Sixteen genomic variations were called in the three normal lung tissues. These variations were confirmed by Sanger capillary sequencing. A mean of 0.5661 exonic variations/Mb and 7.7887 altered genes per sample were identified in the CNC genome sequences of TCGA. In these CNCs, C:G→T:A transitions, which are the genomic signatures of tobacco carcinogen N-methyl-N-nitro-N-nitrosoguanidine, were the predominant nucleotide changes. Twenty five genes in CNCs had a variation rate that exceeded 2%, including ARSD (18.62%), MUC4 (8.79%), and RBMX (7.11%). CNC variations in CTAGE5 and USP17L7 were associated with the poor prognosis of patients with LUSC. Our results uncovered previously unreported genomic variations in CNCs, rather than LUSCs, that may be involved in the development of LUSC.

  2. Binary Black Hole Mergers within the LIGO Horizon: Statistical Properties and prospects for detecting Electromagnetic Counterparts

    Science.gov (United States)

    Perna, Rosalba; Chruslinska, Martyna; Corsi, Alessandra; Belczynski, Krzysztof

    2018-03-01

    Binary black holes (BBHs) are one of the endpoints of isolated binary evolution, and their mergers a leading channel for gravitational wave events. Here, using the evolutionary code STARTRACK, we study the statistical properties of the BBH population from isolated binary evolution for a range of progenitor star metallicities and BH natal kicks. We compute the mass function and the distribution of the primary BH spin a as a result of mass accretion during the binary evolution, and find that this is not an efficient process to spin up BHs, producing an increase by at most a ˜ 0.2-0.3 for very low natal BH spins. We further compute the distribution of merger sites within the host galaxy, after tracking the motion of the binaries in the potentials of a massive spiral, a massive elliptical, and a dwarf galaxy. We find that a fraction of 70-90% of mergers in massive galaxies and of 40-60% in dwarfs (range mostly sensitive to the natal kicks) is expected to occur inside of their hosts. The number density distribution at the merger sites further allows us to estimate the broadband luminosity distribution that BBH mergers would produce, if associated with a kinetic energy release in an outflow, which, as a reference, we assume at the level inferred for the Fermi GBM counterpart to GW150914, with the understanding that current limits from the O1 and O2 runs would require such emission to be produced within a jet of angular size within ≲ 50°.

  3. Life-cycle Analysis of Bioproducts and Their Conventional Counterparts in GREET

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, Jennifer B. [Argonne National Lab. (ANL), Argonne, IL (United States); Adom, Felix [Argonne National Lab. (ANL), Argonne, IL (United States); Sather, Norm [Argonne National Lab. (ANL), Argonne, IL (United States); Han, Jeongwoo [Argonne National Lab. (ANL), Argonne, IL (United States); Snyder, Seth [Argonne National Lab. (ANL), Argonne, IL (United States); He, Chang [Northwestern Univ., Evanston, IL (United States); Gong, Jian [Northwestern Univ., Evanston, IL (United States); Yue, Dajun [Northwestern Univ., Evanston, IL (United States); You, Fengqi [Northwestern Univ., Evanston, IL (United States)

    2015-09-01

    To further expand upon the literature in this field and to develop a platform for bioproduct LCA, we developed LCA results for ten bioproducts produced either from algal glycerol or from corn stover-derived sugars. We used Argonne National Laboratory’s Greenhouse gases, Regulated Emissions, and Energy use in Transportation (GREETTM) model as the platform for this study. The data and calculations reported herein are available to GREET users in a bioproducts module included in the fall 2015 GREET release. This report documents our approach to this analysis and the results. In Chapter 2, we review the process we underwent to select the bioproducts for analysis based on market and technology readiness criteria. In Chapter 3, we review key parameters for production of the two feedstocks we considered: corn stover and algae. Given the lack of publicly available information about the production of bioproducts, which is caused in large part by the emerging nature of the industry, we developed Aspen Plus® simulations of the processes that could be used to produce each bioproduct. From these simulations, we extracted the energy and material flows of these processes, which were important inputs to the GREET bioproducts module. Chapter 4 provides the details of these Aspen Plus simulations. It is important to compare the LCA results for bioproducts to those for their petroleum counterparts. We therefore also developed material and energy flow data for conventional products based mostly on the literature. These data are described in Chapter 5 and are also included in the GREET bioproducts module. In Chapter 6, we present results from this analysis and examine areas for refinement and future research.

  4. Multiband counterparts of two eclipsing ultraluminous X-ray sources in M 51

    Science.gov (United States)

    Urquhart, R.; Soria, R.; Johnston, H. M.; Pakull, M. W.; Motch, C.; Schwope, A.; Miller-Jones, J. C. A.; Anderson, G. E.

    2018-04-01

    We present the discovery and interpretation of ionized nebulae around two ultraluminous X-ray sources in M 51; both sources share the rare property of showing X-ray eclipses by their companion stars and are therefore prime targets for follow-up studies. Using archival Hubble Space Telescope images, we found an elongated, 100-pc-long emission-line structure associated with one X-ray source (CXOM51 J132940.0+471237; ULX-1 for simplicity), and a more circular, ionized nebula at the location of the second source (CXOM51 J132939.5+471244; ULX-2 for simplicity). We observed both nebulae with the Large Binocular Telescope's Multi-Object Double Spectrograph. From our analysis of the optical spectra, we argue that the gas in the ULX-1 bubble is shock-ionized, consistent with the effect of a jet with a kinetic power of ≈2 × 1039 erg s-1. Additional X-ray photoionization may also be present, to explain the strength of high-ionization lines such as He II λ4686 and [Ne V] λ3426. On the other hand, the emission lines from the ULX-2 bubble are typical for photoionization by normal O stars suggesting that the nebula is actually an H II region not physically related to the ULX but is simply a chance alignment. From archival Very Large Array data, we also detect spatially extended, steep-spectrum radio emission at the location of the ULX-1 bubble (consistent with its jet origin), but no radio counterpart for ULX-2 (consistent with the lack of shock-ionized gas around that source).

  5. Refractive predictability of a 3-piece intraocular lens platform versus its 1-piece counterpart.

    Science.gov (United States)

    Mednick, Zale D; Varma, Devesh K; Campos-Möller, Xavier; Ahmed, Iqbal Ike K

    2017-04-01

    To compare the refractive outcomes of a 3-piece acrylic intraocular lens (IOL) with its 1-piece counterpart after phacoemulsification with in-the-bag implantation. Retrospective chart review. One-hundred twenty-six eyes of 95 patients were analyzed in the study, including 60 eyes of 43 patients receiving a 3-piece IOL and 66 eyes of 52 patients receiving a 1-piece IOL. Randomized chart review of all patients who underwent uncomplicated phacoemulsification with in-the-bag IOL implantation with either a 3-piece hydrophobic acrylic IOL (Tecnis ZA9003) or a 1-piece hydrophobic acrylic IOL (Tecnis ZCB00) between 2006 and 2014 in a tertiary ophthalmology care centre in Mississauga, Ontario. Preoperative visual acuity and refraction, anterior chamber depth, axial length, IOL design and power, predicted refraction, postoperative visual acuity, and refraction were recorded. Mean absolute error was 0.40 ± 0.27 in the ZA9003 group and 0.39 ± 0.35 in the ZCB00 group, with no statistically significant difference between the 2 IOLs (p = 0.86). Mean arithmetic error was 0.11 ± 0.47 D in the ZA9003 group and 0.01 ± 0.47 D in the ZCB00 group (p = 0.019). In the ZA9003 group, 23 (38%), 42 (70%), and 52 (87%) of 60 eyes were within 0.25, 0.50, and 0.75 D, respectively, of predicted postoperative refraction. In the ZCB00 group, 32 (48%), 46 (70%), and 56 (85%) of 66 eyes were within 0.25, 0.50, and 0.75 D, respectively, of predicted postoperative refraction (p = 0.2836, p = 1.00, p = 0.8044). The ZA9003 and the ZCB00 have similar mean absolute error and thus appear to have similar refractive predictability. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  6. Reversal of functional disorders by aspiration, expiration and cough reflexes and their voluntary counterparts

    Directory of Open Access Journals (Sweden)

    Zoltan eTomori

    2012-12-01

    Full Text Available Agonal gasping provoked by asphyxia can save ~15% of mammals even from untreated ventricular fibrillation, but it fails to revive infants with sudden infant death syndrome. Our systematic study of airway reflexes in cats and other animals indicated that in addition to cough, there are 2 distinct airway reflexes that may contribute to auto-resuscitation. Gasp- and sniff-like spasmodic inspirations can be elicited by nasopharyngeal stimulation, strongly activating the brainstem generator for inspiration, which is also involved in the control of gasping. This aspiration reflex (AspR is characterized by spasmodic inspiration without subsequent active expiration and can be elicited during agonal gasping, caused by brainstem trans-sections in cats. Stimulation of the larynx can activate the generator for expiration to evoke the expiration reflex, manifesting with prompt expiration without preceding inspiration. Stimulation of the oro-pharynx and lower airways provokes the cough reflex which results from activating of both generators. The powerful potential of the AspR resembling auto-resuscitation by gasping can influence the control mechanisms of vital functions, mediating reversal of various functional disorders.The AspR in cats interrupted hypoxic apnea, laryngo- and bronchospasm, apneusis and even transient asphyxic coma, and can normalize various hypo- and hyper-functional disorders. Introduction of a nasogastric catheter evoked similar spasmodic inspirations in premature infants and interrupted hiccough attacks in adults. Coughing on demand can prevent anaphylactic shock and resuscitate the pertinent subject. Sniff representing nasal inspiratory pressure and maximal inspiratory and expiratory pressures are voluntary counterparts of airway reflexes, and are useful for diagnosis and therapy of various cardio-respiratory and neuromuscular disorders.

  7. Energetic particle counterparts for geomagnetic pulsations of Pc1 and IPDP types

    Directory of Open Access Journals (Sweden)

    T. A. Yahnina

    2003-12-01

    Full Text Available Using the low-altitude NOAA satellite particle data, we study two kinds of localised variations of energetic proton fluxes at low altitude within the anisotropic zone equatorward of the isotropy boundary. These flux variation types have a common feature, i.e. the presence of precipitating protons measured by the MEPED instrument at energies more than 30 keV, but they are distinguished by the fact of the presence or absence of the lower-energy component as measured by the TED detector on board the NOAA satellite. The localised proton precipitating without a low-energy component occurs mostly in the morning-day sector, during quiet geomagnetic conditions, without substorm injections at geosynchronous orbit, and without any signatures of plasmaspheric plasma expansion to the geosynchronous distance. This precipitation pattern closely correlates with ground-based observations of continuous narrow-band Pc1 pulsations in the frequency range 0.1–2 Hz (hereafter Pc1. The precipitation pattern containing the low energy component occurs mostly in the evening sector, under disturbed geomagnetic conditions, and in association with energetic proton injections and significant increases of cold plasma density at geosynchronous orbit. This precipitation pattern is associated with geomagnetic pulsations called Intervals of Pulsations with Diminishing Periods (IPDP, but some minor part of the events is also related to narrow-band Pc1. Both Pc1 and IPDP pulsations are believed to be the electromagnetic ion-cyclotron waves generated by the ion-cyclotron instability in the equatorial plane. These waves scatter energetic protons in pitch angles, so we conclude that the precipitation patterns studied here are the particle counterparts of the ion-cyclotron waves.Key words. Ionosphere (particle precipitation – Magnetospheric physics (energetic particles, precipitating – Space plasma physics (wave-particle interactions

  8. Molecular Characteristics of Malignant Ovarian Germ Cell Tumors and Comparison With Testicular Counterparts: Implications for Pathogenesis

    Science.gov (United States)

    Kraggerud, Sigrid Marie; Hoei-Hansen, Christina E.; Alagaratnam, Sharmini; Skotheim, Rolf I.; Abeler, Vera M.

    2013-01-01

    This review focuses on the molecular characteristics and development of rare malignant ovarian germ cell tumors (mOGCTs). We provide an overview of the genomic aberrations assessed by ploidy, cytogenetic banding, and comparative genomic hybridization. We summarize and discuss the transcriptome profiles of mRNA and microRNA (miRNA), and biomarkers (DNA methylation, gene mutation, individual protein expression) for each mOGCT histological subtype. Parallels between the origin of mOGCT and their male counterpart testicular GCT (TGCT) are discussed from the perspective of germ cell development, endocrinological influences, and pathogenesis, as is the GCT origin in patients with disorders of sex development. Integrated molecular profiles of the 3 main histological subtypes, dysgerminoma (DG), yolk sac tumor (YST), and immature teratoma (IT), are presented. DGs show genomic aberrations comparable to TGCT. In contrast, the genome profiles of YST and IT are different both from each other and from DG/TGCT. Differences between DG and YST are underlined by their miRNA/mRNA expression patterns, suggesting preferential involvement of the WNT/β-catenin and TGF-β/bone morphogenetic protein signaling pathways among YSTs. Characteristic protein expression patterns are observed in DG, YST and IT. We propose that mOGCT develop through different developmental pathways, including one that is likely shared with TGCT and involves insufficient sexual differentiation of the germ cell niche. The molecular features of the mOGCTs underline their similarity to pluripotent precursor cells (primordial germ cells, PGCs) and other stem cells. This similarity combined with the process of ovary development, explain why mOGCTs present so early in life, and with greater histological complexity, than most somatic solid tumors. PMID:23575763

  9. Highly structured and surface modified poly(epsilon-caprolactone) scaffolds derived from co-continuous polymer blends for bone tissue engineering

    Science.gov (United States)

    Mehr, Nima Ghavidel

    Chitosan, an important member of the polysaccharide family was used to alter the chemistry of PCL scaffolds and bring hydrophilicity to the surface. The deposition of a homogeneous chitosan layer on the surface of the PCL scaffolds was carried out using a Layer-by-Layer (LbL) selfassembly of poly(dialyldemethylammunium chloride) (PDADMAC) as cationic and poly(sodium 4-styrenesulfonate) (PSS) as anionic polyelectrolytes. The final negatively charged PSS layer allows for the addition of the positively charged chitosan as the outermost layer. Gravimetric measurements revealed that the addition of up to 3 layers leads to the formation of interdiffusing polyelectrolyte layers which do not allow for the formation of defined positive or negative charges. By increasing the number of polyelectrolyte layers with alternating charges, more welldefined layers are formed. Detailed analyses of O/C, N/C and S/C ratios by X-ray photoelectron spectroscopy (XPS) show that the PSS molecule dominates the surface as the last deposited polyelectrolyte layer at higher number of depositions (n=8), which can later be the surface for the deposition of chitosan. The LbL deposition of the chitosan layer on the LbL coating was then shown to be locally homogeneous at different depths within the scaffolds which also clarified that the LbL method is superior to the dip coating strategy. SEM analysis showed that there is a rough chitosan surface on the 2D solid PCL constructs whose thickness ranges from 550-700 nanometers. These results demonstrate that the application of LbL self-assembly of polyelectrolytes followed by the addition of chitosan as the outermost layer provides a route towards stable and homogeneous surface modification and has the potential to transform a classic fully interconnected porous synthetic polymer material to one with essentially complete chitosanlike surface characteristics. The osteogenic potential of PCL scaffolds with a chitosan coating using Layer-by-Layer (Lb

  10. The second Herschel-ATLAS Data Release - III. Optical and near-infrared counterparts in the North Galactic Plane field

    Science.gov (United States)

    Furlanetto, C.; Dye, S.; Bourne, N.; Maddox, S.; Dunne, L.; Eales, S.; Valiante, E.; Smith, M. W.; Smith, D. J. B.; Ivison, R. J.; Ibar, E.

    2018-05-01

    This paper forms part of the second major public data release of the Herschel Astrophysical Terahertz Large Area Survey (H-ATLAS). In this work, we describe the identification of optical and near-infrared counterparts to the submillimetre detected sources in the 177 deg2 North Galactic Plane (NGP) field. We used the likelihood ratio method to identify counterparts in the Sloan Digital Sky Survey and in the United Kingdom InfraRed Telescope Imaging Deep Sky Survey within a search radius of 10 arcsec of the H-ATLAS sources with a 4σ detection at 250 μm. We obtained reliable (R ≥ 0.8) optical counterparts with r performance of the likelihood ratio method to identify optical and near-infrared counterparts taking into account the depth and area of both input catalogues. Using catalogues with the same surface density of objects in the overlapping ˜25 deg2 area, we obtained that the reliable fraction in the near-infrared (54.8 per cent) is significantly higher than in the optical (36.4 per cent). Finally, using deep radio data which covers a small region of the NGP field, we found that 80-90 per cent of our reliable identifications are correct.

  11. Search for the NIR counterpart to GRB130807A/SWIFTJ1759.2-2736 in quiescence

    NARCIS (Netherlands)

    Greiss, S.; Steeghs, D.; Jonker, P.G.; Maccarone, T.; Torres, M.A.P.; Heinke, C.; Wijnands, R.

    2013-01-01

    In order to search for the counterpart of the transient source SWIFTJ1759.2-2736 (Atel #5268), we investigated near-infrared (NIR) data of the Galactic Bulge region obtained as part of the VVV survey (Minniti et al. 2010, New Astronomy, Volume 15, 433). The observations took place while the source

  12. The Effect of Counterpart Material on the Sliding Wear of TiAlN Coatings Deposited by Reactive Cathodic Pulverization

    Directory of Open Access Journals (Sweden)

    Michell Felipe Cano Ordoñez

    2015-11-01

    Full Text Available This work aims to study the effect of the counterpart materials (100Cr6, Al2O3 and WC-Co on the tribological properties of TiAlN thin films deposited on AISI H13 steel substrate by reactive magnetron co-sputtering. The structural characterization of the TiAlN films, performed by X-ray diffraction, showed (220 textured fcc crystalline structure. The values of hardness and elastic modulus obtained by nanoindentation were 27 GPa and 420 GPa, respectively, which resulted in films with a relatively high resistance to plastic deformation. Ball-on-disk sliding tests were performed using normal loads of 1 N and 3 N, and 0.10 m/s of tangential velocity. The wear coefficient of the films was determined by measuring the worn area using profilometry every 1000 cycles. The mechanical properties and the chemical stability of the counterpart material, debris formation and the contact stress influences the friction and the wear behavior of the studied tribosystems. Increasing the hardness of the counterpart decreases the coefficient of friction (COF due to lower counterpart material transference and tribofilm formation, which is able to support the contact pressure. High shear stress concentration at the coating/substrate interface was reported for higher load promoting failure of the film-substrate system for all tribopairs

  13. Subaru/FOCAS Optical Spectroscopy for a possible IceCube-170922A counterpart TXS 0506+056

    Science.gov (United States)

    Morokuma, Tomoki; Tanaka, Yasuyuki T.; Ohta, Kouji; Matsuoka, Yoshiki; Yamashita, Takuji; Kato, Nanako

    2017-10-01

    We performed optical spectroscopic observations on September 30 and October 1, 2017 (UT) with the 8.2-m Subaru telescope and Faint Object Camera and Spectrograph (FOCAS) for TXS 0506+056 which is a possible counterpart to the IceCube-170922A high-energy neutrino event (Tanaka et al. 2017, ATel #10791).

  14. Coronal type III radio bursts and their X-ray flare and interplanetary type III counterparts

    Science.gov (United States)

    Reid, Hamish A. S.; Vilmer, Nicole

    2017-01-01

    Context. Type III bursts and hard X-rays are both produced by flare energetic electron beams. The link between both emissions has been investigated in many previous studies, but no statistical studies have compared both coronal and interplanetary type III bursts with X-ray flares. Aims: Using events where the coronal radio emission above 100 MHz is exclusively from type III bursts, we revisited some long-standing questions regarding the relation between type III bursts and X-ray flares: Do all coronal type III bursts have X-ray counterparts? What correlation, if any, occurs between radio and X-ray intensities? What X-ray and radio signatures above 100 MHz occur in connection with interplanetary type III bursts below 14 MHz? Methods: We analysed ten years of data from 2002 to 2011 starting with a selection of coronal type III bursts above 100 MHz. We used X-ray flare information from RHESSI >6 keV to make a list of 321 events that have associated type III bursts and X-ray flares, encompassing at least 28% of the initial sample of type III events. We then examined the timings, intensities, associated GOES class, and whether there was an associated interplanetary radio signature in both radio and X-rays. Results: For our 321 events with radio and X-ray signatures, the X-ray emission at 6 keV usually lasted much longer than the groups of type III bursts at frequencies >100 MHz. The selected events were mostly associated with GOES B and C class flares. A weak correlation was found between the type III radio flux at frequencies below 327 MHz and the X-ray intensity at 25-50 keV, with an absence of events at high X-ray intensity and low type III radio flux. The weakness of the correlation is related to the coherent emission mechanism of radio type IIIs which can produce high radio fluxes by low density electron beams. Interplanetary type III bursts (103 SFU), relating to electron beams with more energetic electrons above 25 keV and events where magnetic flux tubes extend

  15. Post-test analysis of the ROSA/LSTF and PKL counterpart test

    Energy Technology Data Exchange (ETDEWEB)

    Carlos, S., E-mail: scarlos@iqn.upv.es [Departament d’Enginyeria Química i Nuclear, Universitat Politècnica de València, Camí de Vera, 14, València Spain (Spain); Querol, A., E-mail: anquevi@iqn.upv.es [Departament d’Enginyeria Química i Nuclear, Universitat Politècnica de València, Camí de Vera, 14, València Spain (Spain); Instituto de Seguridad Industrial, Radiofísica y Medioambiental, Universitat Politècnica de València, Camí de Vera, 14, València (Spain); Gallardo, S., E-mail: sergalbe@iqn.upv.es [Departament d’Enginyeria Química i Nuclear, Universitat Politècnica de València, Camí de Vera, 14, València Spain (Spain); Instituto de Seguridad Industrial, Radiofísica y Medioambiental, Universitat Politècnica de València, Camí de Vera, 14, València (Spain); Sanchez-Saez, F., E-mail: frasansa@etsii.upv.es [Departament d’Enginyeria Química i Nuclear, Universitat Politècnica de València, Camí de Vera, 14, València Spain (Spain); and others

    2016-02-15

    Highlights: • TRACE modelization for PKL and ROSA/LSTF installations. • Secondary-side depressurization as accident management action. • CET vs PCT relation. • Analysis of differences in the vessel models. - Abstract: Experimental facilities are scaled models of commercial nuclear power plants, and are of great importance to improve nuclear power plants safety. Thus, the results obtained in the experiments undertaken in such facilities are essential to develop and improve the models implemented in the thermal-hydraulic codes, which are used in safety analysis. The experiments and inter-comparisons of the simulated results are usually performed in the frame of international programmes in which different groups of several countries simulate the behaviour of the plant under the accidental conditions established, using different codes and models. The results obtained are compared and studied to improve the knowledge on codes performance and nuclear safety. Thus, the Nuclear Energy Agency (NEA), in the nuclear safety work area, auspices several programmes which involve experiments in different experimental facilities. Among the experiments proposed in NEA programmes, one on them consisted of performing a counterpart test between ROSA/LSTF and PKL facilities, with the main objective of determining the effectiveness of late accident management actions in a small break loss of coolant accident (SBLOCA). This study was proposed as a result of the conclusion obtained by the NEA Working Group on the Analysis and Management of Accidents, which analyzed different installations and observed differences in the measurements of core exit temperature (CET) and maximum peak cladding temperature (PCT). In particular, the transient consists of a small break loss of coolant accident (SBLOCA) in a hot leg with additional failure of safety systems but with accident management measures (AM), consisting of a fast secondary-side depressurization, activated by the CET. The paper

  16. Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor.

    Directory of Open Access Journals (Sweden)

    Inna Biela

    Full Text Available Bacterial tRNA-guanine transglycosylase (Tgt catalyses the exchange of the genetically encoded guanine at the wobble position of tRNAs(His,Tyr,Asp,Asn by the premodified base preQ1, which is further converted to queuine at the tRNA level. As eucaryotes are not able to synthesise queuine de novo but acquire it through their diet, eucaryotic Tgt directly inserts the hypermodified base into the wobble position of the tRNAs mentioned above. Bacterial Tgt is required for the efficient pathogenicity of Shigella sp, the causative agent of bacillary dysentery and, hence, it constitutes a putative target for the rational design of anti-Shigellosis compounds. Since mammalian Tgt is known to be indirectly essential to the conversion of phenylalanine to tyrosine, it is necessary to create substances which only inhibit bacterial but not eucaryotic Tgt. Therefore, it seems of utmost importance to study selectivity-determining features within both types of proteins. Homology models of Caenorhabditis elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis Tgt numbering by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities. In the present study we have created mutated variants of Z. mobilis Tgt in order to investigate the impact of a Cys158Val and a Val233Gly exchange on catalytic activity and substrate specificity. Using enzyme kinetics and X-ray crystallography, we gained evidence that the Cys158Val mutation reduces the affinity to preQ1 while leaving the affinity to guanine unaffected. The Val233Gly exchange leads to an enlarged substrate binding pocket, that is necessary to accommodate queuine in a conformation compatible with the intermediately covalently bound tRNA molecule. Contrary to our expectations, we found that a priori queuine is recognised by the binding pocket of bacterial Tgt without, however, being used as a substrate.

  17. Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

    Directory of Open Access Journals (Sweden)

    Zahra Lotfollahi

    2017-01-01

    Full Text Available Giant magnetoimpedance (GMI has been proposed as a powerful technique for biosensing. In GMI biosensors based on the magnetic label detection the change of the impedance of sensitive element under the application of an external magnetic field was analyzed in the presence of magnetic nanoparticles in a test solution. Amorphous ribbon-based GMI biodetectors have an advantage of low operation frequency and low cost. In this work, magnetic and GMI properties of amorphous Co68.6Fe3.9Mo3.0Si12.0B12.5 ribbons were studied in as-quenched and surface modified states both without and in the presence of maghemite ferrofluid. After the surface modification the coercivity was slightly increased and saturation magnetization decreased in good agreement with increase of the surface roughness, a decrease of magnetic elements concentrations in the surface layer, and formation of a surface protective oxide layer. The GMI difference for as-quenched ribbons in absence and in the presence of ferrofluid was measurable for the frequency range of 2 to 10 MHz and the current intensities of 1 to 20 mA. Although the proposed surface modification by the ultrasound treatment did not improve the sensitivity limit for ferrofluid detection, it did not decrease it either.

  18. Gamma-ray Burst and Gravitational Wave Counterpart Prospects in the MeV Band with AMEGO

    Science.gov (United States)

    Racusin, Judith; AMEGO Team

    2018-01-01

    The All-sky Medium Energy Gamma-ray Observatory (AMEGO) Probe mission concept is uniquely suited to address open questions in Gamma-ray Burst (GRB) science including the search for counterparts to gravitational-wave events. AMEGO is a wide field of view instrument (~60 deg radius) with a broad energy range (~200 keV to >10 GeV) and excellent continuum sensitivity. The sensitivity improvement will allow for probes of GRB emission mechanisms and jet composition in ways that have not been accessible with previous instruments. Potential for polarization measurement may also have profound impacts on the understanding of GRB mechanisms. AMEGO will also be an excellent facility for the search for gravitational wave counterparts to binary mergers including at least one neutron star, which are thought to produce short duration GRBs. This poster will describe how the AMEGO will advance these fields.

  19. Comparison of Physical Fitness Parameters with EUROFIT Test Battery of Male Adolescent Soccer Players and Sedentary Counterparts

    Directory of Open Access Journals (Sweden)

    Özgür ERİKOĞLU

    2015-09-01

    Full Text Available The aim of this study was to compare physical fitness parameters of male adolescent soccer players and sedentary counterparts. A total of 26 male adolescents participated in this study voluntarily: Active soccer players (n: 3, age x : 13,00 ± 0,00 and sedentary counterparts (n: 13, age x :12,92 ± 0,75. The EUROFIT test battery was used to determine physical fitness. The test battery includes body height and weight measurements, touching the discs, flamingo balan ce, throwing health ball, vertical jumping, sit and reach, sit - up for 30 s, 20 meter sprint run, and 20 meter shuttle run tests. Data were analyzed by Mann Whitney U test. Significance was defined as p.05. In conclusion, children who do sports are more successful on most of the fitness parameters than sedentary children.

  20. Search of MeV-GeV counterparts of TeV sources with AGILE in pointing mode

    Science.gov (United States)

    Rappoldi, A.; Lucarelli, F.; Pittori, C.; Longo, F.; Cattaneo, P. W.; Verrecchia, F.; Tavani, M.; Bulgarelli, A.; Chen, A. W.; Colafrancesco, S.; Donnarumma, I.; Giuliani, A.; Morselli, A.; Sabatini, S.; Vercellone, S.

    2016-03-01

    Context. Known TeV sources detected by major Čerenkov telescopes are investigated to identify possible MeV-GeV γ-ray counterparts. Aims: A systematic study of the known sources in the web-based TeVCat catalog has been performed to search for possible γ-ray counterparts on the AGILE data collected during the first period of operations in observing pointing mode. Methods: For each TeV source, a search for a possible γ-ray counterpart that is based on a multi-source maximum likelihood algorithm is performed on the AGILE data taken with the GRID instrument from July 2007 to October 2009. Results: In the case of high-significance detection, the average γ-ray flux is estimated. For cases of low-significance detection the 95% confidence level (CL) flux upper limit is given. 52 TeV sources out of 152 (corresponding to ~34% of the analysed sample) show a significant excess in the AGILE data covering the pointing observation period. Conclusions: This analysis found 26 new AGILE sources with respect to the AGILE reference catalogs, 15 of which are galactic, 7 are extragalactic and 4 are unidentified. Detailed tables with all available information on the analysed sources are presented. An interactive online version of the considered source list including all the analysis results is also available at the website http://www.asdc.asi.it/agiletevcat/

  1. VLT observations of the magnetar CXO J164710.2-455216 and the detection of a candidate infrared counterpart

    Science.gov (United States)

    Testa, V.; Mignani, R. P.; Hummel, W.; Rea, N.; Israel, G. L.

    2018-01-01

    We present deep observations of the field of the magnetar CXO J164710.2-455216 in the star cluster Westerlund 1, obtained in the near-infrared with the adaptive optics camera NACO@VLT. We detected a possible candidate counterpart at the Chandra position of the magnetar, of magnitudes J = 23.5 ± 0.2, H = 21.0 ± 0.1 and KS = 20.4 ± 0.1. The KS-band measurements available for two epochs (2006 and 2013) do not show significant signs of variability but only a marginal indication that the flux varied (at the 2σ level), consistent with the fact that the observations were taken when CXO J164710.2-455216 was in quiescence. At the same time, we also present colour-magnitude and colour-colour diagrams in the J, H and KS bands from the 2006 epoch only, the only one with observations in all three bands, showing that the candidate counterpart lies in the main bulk of objects describing a relatively well-defined sequence. Therefore, based on its colours and lack of variability, we cannot yet associate the candidate counterpart to CXO J164710.2-455216. Future near-infrared observations of the field, following up a source outburst, would be crucial to confirm the association with the detection of near-infrared variability and colour evolution.

  2. Health and functional status and utilization of health care services among holocaust survivors and their counterparts in Israel.

    Science.gov (United States)

    Iecovich, Esther; Carmel, Sara

    2010-01-01

    To examine differences in health and functional status and in utilization of health services between holocaust survivors and their counterparts; and (b) to investigate if holocaust survivor status is a significant predictor of health status, functional status, and utilization of health services. The study included 1255 respondents of whom 272 were holocaust survivors. Interviews were conducted face-to-face at the respondents' homes. Participants were asked about their health (self-rated health and comorbidity) and functional (ADL and IADL) status, utilization of inpatient and outpatient health care services, age, gender, education, marital status, length of residence in Israel, and if they were holocaust survivors. Holocaust survivors, who were frailer and more chronically ill compared to their counterparts, visited their family physician and the nurse at the health care clinic more often than their counterparts did, and received more homecare services. Yet, there were no differences between them in the utilization of other health care services such as visits to specialists, emergency department, and hospitalizations. Holocaust survivors are more homebound due to more morbidity and functional limitations and therefore receive more health home care services that offset the utilization of other health services. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  3. A thermodynamic counterpart of the Axelrod model of social influence: The one-dimensional case

    Science.gov (United States)

    Gandica, Y.; Medina, E.; Bonalde, I.

    2013-12-01

    We propose a thermodynamic version of the Axelrod model of social influence. In one-dimensional (1D) lattices, the thermodynamic model becomes a coupled Potts model with a bonding interaction that increases with the site matching traits. We analytically calculate thermodynamic and critical properties for a 1D system and show that an order-disorder phase transition only occurs at T=0 independent of the number of cultural traits q and features F. The 1D thermodynamic Axelrod model belongs to the same universality class of the Ising and Potts models, notwithstanding the increase of the internal dimension of the local degree of freedom and the state-dependent bonding interaction. We suggest a unifying proposal to compare exponents across different discrete 1D models. The comparison with our Hamiltonian description reveals that in the thermodynamic limit the original out-of-equilibrium 1D Axelrod model with noise behaves like an ordinary thermodynamic 1D interacting particle system.

  4. Canine spontaneous head and neck squamous cell carcinomas represent their human counterparts at the molecular level.

    Directory of Open Access Journals (Sweden)

    Deli Liu

    2015-06-01

    Full Text Available Spontaneous canine head and neck squamous cell carcinoma (HNSCC represents an excellent model of human HNSCC but is greatly understudied. To better understand and utilize this valuable resource, we performed a pilot study that represents its first genome-wide characterization by investigating 12 canine HNSCC cases, of which 9 are oral, via high density array comparative genomic hybridization and RNA-seq. The analyses reveal that these canine cancers recapitulate many molecular features of human HNSCC. These include analogous genomic copy number abnormality landscapes and sequence mutation patterns, recurrent alteration of known HNSCC genes and pathways (e.g., cell cycle, PI3K/AKT signaling, and comparably extensive heterogeneity. Amplification or overexpression of protein kinase genes, matrix metalloproteinase genes, and epithelial-mesenchymal transition genes TWIST1 and SNAI1 are also prominent in these canine tumors. This pilot study, along with a rapidly growing body of literature on canine cancer, reemphasizes the potential value of spontaneous canine cancers in HNSCC basic and translational research.

  5. Preparation, characteristics and electrochemical properties of surface-modified LiMn2O4 by doped LiNi0.05Mn1.95O4

    International Nuclear Information System (INIS)

    Yuan, Y.F.; Wu, H.M.; Guo, S.Y.; Wu, J.B.; Yang, J.L.; Wang, X.L.; Tu, J.P.

    2008-01-01

    The surface-modified spinel LiMn 2 O 4 by doped LiNi 0.05 Mn 1.95 O 4 was prepared by a tartaric acid gel method. Transmission electron microscope (TEM) images indicated that some small particles with 100-200 nm in diameter modified the surface of large particle LiMn 2 O 4 . Energy dispersive spectrometry (EDS) showed that the particles were LiNi 0.05 Mn 1.95 O 4 . Electrochemical properties of LiNi 0.05 Mn 1.95 O 4 -modified spinel LiMn 2 O 4 were intensively investigated by the galvanostatic charge-discharge tests, cyclic voltammetry (CV) and AC impedance measurements. The doped LiNi 0.05 Mn 1.95 O 4 -modified LiMn 2 O 4 cathode delivered the same initial discharge capacity as the unmodified LiMn 2 O 4 , but its cyclic stability was evidently improved, the capacity retention ratio reached 96% after 20 cycles, being higher than 89% of the unmodified LiMn 2 O 4 . Cyclic voltammograms of the LiNi 0.05 Mn 1.95 O 4 -modified LiMn 2 O 4 did not markedly change while the semicircle diameter of AC impedance spectra evidently decreased after 20 cycles, which showed that the surface modification with LiNi 0.05 Mn 1.95 O 4 improved the electrochemical activity and cycling stability of LiMn 2 O 4 .

  6. A facile method to prepare "green" nano-phosphors with a large Stokes-shift and solid-state enhanced photophysical properties based on surface-modified gold nanoclusters.

    Science.gov (United States)

    Cheng, C H; Huang, H Y; Talite, M J; Chou, W C; Yeh, J M; Yuan, C T

    2017-12-15

    Colloidal nano-materials, such as quantum dots (QDs) have been applied to light-conversion nano-phosphors due to their unique tunable emission. However, most of the QDs involve toxic elements and are synthesized in a hazardous solvent. In addition, conventional QD nano-phosphors with a small Stokes shift suffered from reabsorption losses and aggregation-induced quenching in the solid state. Here, we demonstrate a facile, matrix-free method to prepare eco-friendly nano-phosphors with a large Stokes shift based on aqueous thiolate-stabilized gold nanoclusters (GSH-AuNCs) with simple surface modifications. Our method is just to drop GSH-AuNCs solution on the aluminum foil and then surface-modified AuNCs (Al-GSH-AuNCs) can be spontaneously precipitated out of the aqueous solution. Compared with pristine GSH-AuNCs in solution, the Al-GSH-AuNCs exhibit enhanced solid-state PL quantum yields, lengthened PL lifetime, and spectral blue shift, which can be attributed to the aggregation-induced emission enhancement facilitated by surface modifications. Such surface-treatment induced aggregation of AuNCs can restrict the surface-ligand motion, leading to the enhancement of PL properties in the solid state. In addition, the Al-GSH-AuNCs nano-phosphors with a large Stokes shift can mitigate the aggregation-induced PL quenching and reabsorption losses, which would be potential candidates for "green" nano-phosphors. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Professional Soccer Player Neuromuscular Responses and Perceptions to Acute Whole Body Vibration Differ from Amateur Counterparts.

    Science.gov (United States)

    Cloak, Ross; Lane, Andrew; Wyon, Matthew

    2016-03-01

    Acute whole body vibration (WBV) is an increasingly popular training technique amongst athletes immediately prior to performance and during scheduled breaks in play. Despite its growing popularity, evidence to demonstrate its effectiveness on acute neuromuscular responses is unclear, and suggestions that athlete ability impacts effectiveness warrant further investigation. The purpose of this study was to compare the neuromuscular effects of acute WBV and perceptions of whether WBV is an effective intervention between amateur and professional soccer players. Participants were 44 male soccer players (22 professional and 22 amateur; age: 23.1 ± 3.7 years, body mass: 75.6 ± 8.8 kg and height: 1.77 ± 0.05 m). Participants in each group were randomly assigned to either an intervention of 3 x 60 s of WBV at 40 Hz (8mm peak-to-peak displacement) or control group. Peak knee isometric force, muscle activation and post activation potentiation (PAP) of the knee extensors along with self-report questionnaire of the perceived benefits of using the intervention were collected. A three-way ANOVA with repeated measures revealed professional players demonstrated a significant 10.6% increase (p amateur players. A significant difference (p amateur players were reported across measurements. Results also indicated professional players reported significantly stronger positive beliefs in the effectiveness of the WBV intervention (p amateur players. Acute WBV elicited a positive neuromuscular response amongst professional players identified by PAP and improvements in knee isometric peak force as well as perceived benefits of the intervention, benefits not found among amateur players. Key pointsAcute WBV improves knee extensor peak isometric force output and PAP amongst professional and not amateur soccer playersProfessional players perceived acute WBV as more beneficial to performance than amateur playersIsometric strength,vibration intensity and duration appear to influence results

  8. DA 495: An Aging Pulsar Wind Nebula with Possible TeV Gamma-Ray Counterpart

    Science.gov (United States)

    Coerver, Anna; Mori, Kaya; Hailey, Charles; Gotthelf, Eric; Mukherjee, Reshmi; Hui, Michelle; Dingus, Brenda; Goodman, Jordan; NuSTAR, HAWC, VERITAS

    2018-01-01

    A pulsar wind nebula is created when a high-mass star collapses and forms an isolated neutron star surrounded by a relativistic particle wind. DA 495 is thought to be such an object, although no pulsations have been detected. DA 495 was first detected in the radio band and is characterized by an annular radio morphology with a radio emission dip in the center. It has been theorized that the wind nebula has an unusually high magnetization of 1.3 mG, and the age of the PWN has been estimated from the 1.3 GHz energy break to be approximately 20 kyr. With such a high wind magnetization, one would expect synchrotron radiation to fall off fairly quickly, yet NuSTAR (the Nuclear Spectroscopic Telescope Array) detected hard X-rays at energies greater than 10 keV, and a study of the Galactic Plane by the HAWC very-high-energy (VHE) gamma-ray telescope revealed a source coincident with DA 495 at energies greater than 10 TeV. This source was also detected at TeV energies by the VERITAS gamma-ray telescope. DA 495 was detected in the X-ray up to 10 keV by both Chandra and XMM-Newton X-ray telescopes before NuSTAR performed follow-up observations of the region in June 2017. DA 495 is one of the first TeV sources observed by the NuSTAR-HAWC-VERITAS Galactic Legacy collaboration. We carried out spectral and imaging analysis of both NuSTAR and Chandra data on DA 495 and will present results of our study of DA 495.

  9. Achilles tendon injuries in elite athletes: lessons in pathophysiology from their equine counterparts.

    Science.gov (United States)

    Patterson-Kane, Janet C; Rich, Tina

    2014-01-01

    Superficial digital flexor tendon (SDFT) injury in equine athletes is one of the most well-accepted, scientifically supported companion animal models of human disease (i.e., exercise-induced Achilles tendon [AT] injury). The SDFT and AT are functionally and clinically equivalent (and important) energy-storing structures for which no equally appropriate rodent, rabbit, or other analogues exist. Access to equine tissues has facilitated significant advances in knowledge of tendon maturation and aging, determination of specific exercise effects (including early life), and definition of some of the earliest stages of subclinical pathology. Access to human surgical biopsies has provided complementary information on more advanced phases of disease. Importantly, equine SDFT injuries are only a model for acute ruptures in athletes, not the entire spectrum of human tendonopathy (including chronic tendon pain). In both, pathology begins with a potentially prolonged phase of accumulation of (subclinical) microdamage. Recent work has revealed remarkably similar genetic risk factors, including further evidence that tenocyte dysfunction plays an active role. Mice are convenient but not necessarily accurate models for multiple diseases, particularly at the cellular level. Mechanistic studies, including tendon cell responses to combinations of exercise-associated stresses, require a more thorough investigation of cross-species conservation of key stress pathway auditors. Molecular evidence has provided some context for the poor performance of mouse models; equines may provide better systems at this level. The use of horses may be additionally justifiable based on comparable species longevity, lifestyle factors, and selection pressure by similar infectious agents (e.g., herpesviruses) on general cell stress pathway evolution. © The Author 2014. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions

  10. A challenge to identify an optical counterpart of the gravitational wave event GW151226 with Hyper Suprime-Cam†

    Science.gov (United States)

    Utsumi, Yousuke; Tominaga, Nozomu; Tanaka, Masaomi; Morokuma, Tomoki; Yoshida, Michitoshi; Asakura, Yuichiro; Finet, François; Furusawa, Hisanori; Kawabata, Koji S.; Liu, Wei; Matsubayashi, Kazuya; Moritani, Yuki; Motohara, Kentaro; Nakata, Fumiaki; Ohta, Kouji; Terai, Tsuyoshi; Uemura, Makoto; Yasuda, Naoki

    2018-01-01

    We present the results of detailed analysis of an optical imaging survey conducted using the Subaru/Hyper Suprime-Cam (HSC) that aimed to identify an optical counterpart to the gravitational wave event GW151226. In half a night, the i- and z-band imaging survey by HSC covered 63.5 deg2 of the error region, which contains about 7% of the LIGO localization probability, and the same field was observed in three different epochs. The detectable magnitude of the candidates in a differenced image is evaluated as i ˜ 23.2 mag for the requirement of at least two 5 σ detections, and 1744 candidates are discovered. Assuming a kilonova as an optical counterpart, we compare the optical properties of the candidates with model predictions. A red and rapidly declining light curve condition enables the discrimination of a kilonova from other transients, and a small number of candidates satisfy this condition. The presence of stellar-like counterparts in the reference frame suggests that the surviving candidates are likely to be flare stars. The fact that most of those candidates are in the galactic plane, |b| < 5°, supports this interpretation. We also check whether the candidates are associated with the nearby GLADE galaxies, which reduces the number of contaminants even with a looser color cut. When a better probability map (with localization accuracy of ˜50 deg2) is available, kilonova searches of up to approximately 200 Mpc will become feasible by conducting immediate follow-up observations with an interval of 3-6 d.

  11. DISCOVERY OF THE OPTICAL/ULTRAVIOLET/GAMMA-RAY COUNTERPART TO THE ECLIPSING MILLISECOND PULSAR J1816+4510

    Energy Technology Data Exchange (ETDEWEB)

    Kaplan, D. L.; Kotulla, R.; Biwer, C. M.; Day, D. F. [Physics Department, University of Wisconsin-Milwaukee, Milwaukee WI 53211 (United States); Stovall, K.; Dartez, L.; Ford, A. J.; Garcia, A.; Jenet, F. A. [Center for Advanced Radio Astronomy and Department of Physics and Astronomy, University of Texas at Brownsville, Brownsville, TX 78520 (United States); Ransom, S. M. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22901 (United States); Roberts, M. S. E. [Eureka Scientific, Inc., 2452 Delmer Street, Suite 100, Oakland, CA 94602-3017 (United States); Archibald, A. M.; Karako, C.; Kaspi, V. M.; Lynch, R. S. [Department of Physics, McGill University, 3600 University Street, Montreal, QC H3A 2T8 (Canada); Boyles, J.; Lorimer, D. R.; McLaughlin, M. A. [Department of Physics, West Virginia University, White Hall, 115 Willey Street, Morgantown, WV 26506 (United States); Hessels, J. W. T.; Kondratiev, V. I., E-mail: kaplan@uwm.edu [ASTRON, the Netherlands Institute for Radio Astronomy, Postbus 2, 7990 AA, Dwingeloo (Netherlands); and others

    2012-07-10

    The energetic, eclipsing millisecond pulsar J1816+4510 was recently discovered in a low-frequency radio survey with the Green Bank Telescope. With an orbital period of 8.7 hr and a minimum companion mass of 0.16 M{sub Sun }, it appears to belong to an increasingly important class of pulsars that are ablating their low-mass companions. We report the discovery of the {gamma}-ray counterpart to this pulsar and present a likely optical/ultraviolet counterpart as well. Using the radio ephemeris, we detect pulsations in the unclassified {gamma}-ray source 2FGL J1816.5+4511, implying an efficiency of {approx}25% in converting the pulsar's spin-down luminosity into {gamma}-rays and adding PSR J1816+4510 to the large number of millisecond pulsars detected by Fermi. The likely optical/UV counterpart was identified through position coincidence (<0.''1) and unusual colors. Assuming that it is the companion, with R = 18.27 {+-} 0.03 mag and effective temperature {approx}> 15,000 K, it would be among the brightest and hottest of low-mass pulsar companions and appears qualitatively different from other eclipsing pulsar systems. In particular, current data suggest that it is a factor of two larger than most white dwarfs of its mass but a factor of four smaller than its Roche lobe. We discuss possible reasons for its high temperature and odd size, and suggest that it recently underwent a violent episode of mass loss. Regardless of origin, its brightness and the relative unimportance of irradiation make it an ideal target for a mass, and hence a neutron star mass, determination.

  12. QUEST FOR COSMOS SUBMILLIMETER GALAXY COUNTERPARTS USING CARMA AND VLA: IDENTIFYING THREE HIGH-REDSHIFT STARBURST GALAXIES

    International Nuclear Information System (INIS)

    Smolčić, V.; Navarrete, F.; Bertoldi, F.; Aravena, M.; Sheth, K.; Ilbert, O.; Yun, M. S.; Salvato, M.; Finoguenov, A.; McCracken, H. J.; Diener, C.; Aretxaga, I.; Hughes, D.; Wilson, G.; Riechers, D. A.; Capak, P.; Scoville, N. Z.; Karim, A.; Schinnerer, E.

    2012-01-01

    We report on interferometric observations at 1.3 mm at 2''-3'' resolution using the Combined Array for Research in Millimeter-wave Astronomy. We identify multi-wavelength counterparts of three submillimeter galaxies (SMGs; F 1m > 5.5 mJy) in the COSMOS field, initially detected with MAMBO and AzTEC bolometers at low, ∼10''-30'', resolution. All three sources—AzTEC/C1, Cosbo-3, and Cosbo-8—are identified to coincide with positions of 20 cm radio sources. Cosbo-3, however, is not associated with the most likely radio counterpart, closest to the MAMBO source position, but with that farther away from it. This illustrates the need for intermediate-resolution (∼2'') mm-observations to identify the correct counterparts of single-dish-detected SMGs. All of our three sources become prominent only at NIR wavelengths, and their mm-to-radio flux based redshifts suggest that they lie at redshifts z ∼> 2. As a proof of concept, we show that photometric redshifts can be well determined for SMGs, and we find photometric redshifts of 5.6 ± 1.2, 1.9 +0.9 –0.5 , and ∼4 for AzTEC/C1, Cosbo-3, and Cosbo-8, respectively. Using these we infer that these galaxies have radio-based star formation rates of ∼> 1000 M ☉ yr –1 and IR luminosities of ∼10 13 L ☉ consistent with properties of high-redshift SMGs. In summary, our sources reflect a variety of SMG properties in terms of redshift and clustering, consistent with the framework that SMGs are progenitors of z ∼ 2 and today's passive galaxies.

  13. Comparison of nutritional value of transgenic peanut expressing bar and rcg3 genes with non-transgenic counterparts

    International Nuclear Information System (INIS)

    Robab, U.E.; )

    2014-01-01

    The transgenic peanut plants expressing bar and rcg3 genes were subjected to assessment of any change in nutritional value of the crop at various locations. The protein and fat contents of transgenic lines were compared with the non-transgenic parent varieties. Protein content in the transgenic lines was higher as compared to that in non-transgenic counterparts and differences among locations for fat and protein content were significant. No differences among fatty acids were recorded for genes, events and locations. Irrespective of small differences, all the values were in range described for this crop and transgenic lines appeared to be substantially equivalent to non-transgenic parent varieties. (author)

  14. Interstimulus interval dependence of the auditory vertex response and its magnetic counterpart: implications for their neural generation.

    Science.gov (United States)

    Hari, R; Kaila, K; Katila, T; Tuomisto, T; Varpula, T

    1982-11-01

    Auditory vertex responses elicited by short tone bursts were compared with their magnetic counter parts. Special attention was paid to the behaviour of the N100 deflection of the response. Electrical responses were recorded from scalp locations Fp2, Fz, Cz, Pz, C4 and T4 and the magnetic responses half way between P4 and T6, at a point where the response has one of its amplitude extrema. Different ISIs (from 1 to 16 sec) were applied in order to differentiate specific and nonspecific evoked potential components from each other. The main results were as follows: (1) The scalp distsribution of the electical vertex response depends on the ISI used: with frequent stimulation there are no marked differences in the amplitudes of N100 between frontal and central areas but with long ISIs the amplitude maxima move to the vertex. (2) The magnetic responses also show a clear ISI dependence. The magnetic counterpart of N100 saturates at shorter ISIs than N100 recorded from the vertex. Independent of the ISI the magnetic counterpart of P200 is constantly very small. On the basis of the different sensitivities of the EEG and MEG to current sources of different orientations it is concluded that the auditory vertex response contains both modality specific and non-specific components. Experimental conditions, especially the ISI used, determine the relative contributions of these components to the potential recorded on the scalp.

  15. An Enhanced Method for Scheduling Observations of Large Sky Error Regions for Finding Optical Counterparts to Transients

    Energy Technology Data Exchange (ETDEWEB)

    Rana, Javed; Singhal, Akshat; Gadre, Bhooshan; Bhalerao, Varun; Bose, Sukanta, E-mail: javed@iucaa.in [Inter-University Centre for Astronomy and Astrophysics, Post Bag 4, Ganeshkhind, Pune 411 007 (India)

    2017-04-01

    The discovery and subsequent study of optical counterparts to transient sources is crucial for their complete astrophysical understanding. Various gamma-ray burst (GRB) detectors, and more notably the ground-based gravitational wave detectors, typically have large uncertainties in the sky positions of detected sources. Searching these large sky regions spanning hundreds of square degrees is a formidable challenge for most ground-based optical telescopes, which can usually image less than tens of square degrees of the sky in a single night. We present algorithms for better scheduling of such follow-up observations in order to maximize the probability of imaging the optical counterpart, based on the all-sky probability distribution of the source position. We incorporate realistic observing constraints such as the diurnal cycle, telescope pointing limitations, available observing time, and the rising/setting of the target at the observatory’s location. We use simulations to demonstrate that our proposed algorithms outperform the default greedy observing schedule used by many observatories. Our algorithms are applicable for follow-up of other transient sources with large positional uncertainties, such as Fermi -detected GRBs, and can easily be adapted for scheduling radio or space-based X-ray follow-up.

  16. Life-cycle fossil energy consumption and greenhouse gas emissions of bioderived chemicals and their conventional counterparts.

    Science.gov (United States)

    Adom, Felix; Dunn, Jennifer B; Han, Jeongwoo; Sather, Norm

    2014-12-16

    Biomass-derived chemical products may offer reduced environmental impacts compared to their fossil-derived counterparts and could improve profit margins at biorefineries when coproduced with higher-volume, lower-profit margin biofuels. It is important to assess on a life-cycle basis the energy and environmental impacts of these bioproducts as compared to conventional, fossil-derived products. We undertook a life-cycle analysis of eight bioproducts produced from either algal-derived glycerol or corn stover-derived sugars. Selected on the basis of technology readiness and market potential, the bioproducts are propylene glycol, 1,3-propanediol, 3-hydroxypropionic acid, acrylic acid, polyethylene, succinic acid, isobutanol, and 1,4-butanediol. We developed process simulations to obtain energy and material flows in the production of each bioproduct and examined sensitivity of these flows to process design assumptions. Conversion process data for fossil-derived products were based on the literature. Conversion process data were combined with upstream parameters in the Greenhouse gases, Regulated Emissions, and Energy use in Transportation (GREET) model to generate life-cycle greenhouse gas (GHG) emissions and fossil energy consumption (FEC) for each bioproduct and its corresponding petroleum-derived product. The bioproducts uniformly offer GHG emissions reductions compared to their fossil counterparts ranging from 39 to 86% on a cradle-to-grave basis. Similarly, FEC was lower for bioproducts than for conventional products.

  17. The Effect of the Negotiator's Social Power as a Function of the Counterpart's Emotional Reactions in a Computer Mediated Negotiation

    Directory of Open Access Journals (Sweden)

    Shlomo Hareli

    2013-11-01

    Full Text Available A negotiator’s own power and their counterpart’s emotional reaction to the negotiation both influence the outcome of negotiations. The present research addressed the question of their relative importance. On one hand, social power should be potent regardless of the other’s emotions. On the other hand, the counterpart’s emotional reactions inform about the ongoing state of the negotiation, and as such are more diagnostic than the more distal power cue. In a simulated computer mediated negotiation, 248 participants assumed the role of a vendor of computerized avionics test equipment and their objective was to negotiate the price, the warranty period, and the number of software updates that the buyer will receive free of charge. Participants negotiated the sale after being primed with either high or low power or not primed at all (control condition. They received information that their counterpart was either happy or angry or emotionally neutral. The findings showed that even though power was an important factor at the start of negotiations, the informative value of emotion information took precedence over time. This implies that emotional information may erase any advantage that counterparts have in a negotiation thanks to their higher social power.

  18. Distribution of apparent activation energy counterparts during thermo - And thermo-oxidative degradation of Aronia melanocarpa (black chokeberry).

    Science.gov (United States)

    Janković, Bojan; Marinović-Cincović, Milena; Janković, Marija

    2017-09-01

    Kinetics of degradation for Aronia melanocarpa fresh fruits in argon and air atmospheres were investigated. The investigation was based on probability distributions of apparent activation energy of counterparts (ε a ). Isoconversional analysis results indicated that the degradation process in an inert atmosphere was governed by decomposition reactions of esterified compounds. Also, based on same kinetics approach, it was assumed that in an air atmosphere, the primary compound in degradation pathways could be anthocyanins, which undergo rapid chemical reactions. A new model of reactivity demonstrated that, under inert atmospheres, expectation values for ε a occured at levels of statistical probability. These values corresponded to decomposition processes in which polyphenolic compounds might be involved. ε a values obeyed laws of binomial distribution. It was established that, for thermo-oxidative degradation, Poisson distribution represented a very successful approximation for ε a values where there was additional mechanistic complexity and the binomial distribution was no longer valid. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Differential production of proteolytic enzymes by normal human fibroblasts and their counterparts transformed by treatment with 60Co gamma rays

    International Nuclear Information System (INIS)

    Nishitani, Koji; Namba, Masayoshi; Ohkubo, Shigeki; Kimoto, Tetsuo

    1985-01-01

    Production of proteolytic enzymes by human fibroblasts in the process of transformation was investigated. The cells used were normal human fibroblasts (KSM-6) and their in vitro counterparts transformed by treatment with 60 Co gamma rays (KMST-6). Cells seeded by treatment with EDTA were cultured in a serum free medium. Proteolytic enzymes in the culture medium of cells were assayed using a synthetic substrate, N-α-(p-tosyl)-L-arginine ( 3 H) methyl ester hydrochloride. The transformed cells (KMST-6) produced a larger amount of enzymes than normal cells (KMS-6). The enzyme production in both cell lines was high in the exponential growth stage and then decreased as the cells reached confluency. The proteolytic enzymes produced by these cells were trypsin- and thrombin-like enzymes. Cell growth of KMST-6 or KMS-6 was not inhibited by the addition of protease inhibitors to the culture medium. (author)

  20. RODOS - The domestic counterpart

    International Nuclear Information System (INIS)

    Vamanu, Dan V.

    1999-01-01

    One term of reference for validly teaming up with Project RODOS (Real-Time-On-Line Decision Support System for Nuclear Emergencies in Europe) is to institutionally - contribute research initiatives geared towards emulating the RODOS functions on novel conceptual pathways, expand system's coverage of issues that are relevant in a nuclear crisis management and bring in a domestic perspective on how the system may best perform in each and every national - i.e. legal, managerial, logistic and cultural environment. On this line, one reviews the approach taken in the IFIN-HH RODOS Group to address the challenge, as well a number of representative outputs. These include: i) A phase-one, pre-RODOS, period (1990 - 1994), involving topical field orientation, feasibility demonstrations and expertise acquisition by hands-on training in environmental radiology modeling and DSS code development, the resulting products - codes in the 'APUD' and 'ACA-IFA' family, including custom versions developed by appointment of the IAEA Safety Section and AECL-Research, Ontario, Canada - being favourably reviewed by the NEA/OECD Data Bank; ii) A phase-two, upgrading and consolidation period (1994 -1996), assisted by the IAEA fellowship system and the US Government via the Nuclear Regulatory Commission in Washington, D.C, having on record an effective participation in the development of the US NRC, EPA, and DOE's 'FRMAC Assessment Manual - The Federal manual for Assessing Environmental Data during a Radiological Emergency', and the 'RTM-95 International Technical Response Manual', and the research initiative of developing a software support for the manuals' implementation - the codes 'ROBOT' (Rule-Oriented Basic Operational Tool); iii) A phase-three period (1996 - ), evolving within the RODOS framework and featuring, inter alia: (a) the application of the ROBOT concept in the development of a standalone software platform, code-named NOTEPAD for DSS support in field operations, nuclear accident drills, expert service provision on issues such as siting and health and environmental impact assessment, mainly targeting the accident source near-field; (b) a likewise experiment in the summary assessment of the far-field consequences of an atmospheric release ('QuickFIX'); (c) a research initiative in modeling the dispersion in complex topography terrains, using linearized equations of the mesoscale meteorology and heuristic concepts; (d) the development, by appointment of the Swiss Federal Institute of Technology ETH-Zurich and under the joint guidance of Institut de protection et de surete nucleaire CEA-IPSN and Kernforschungszentrum Karlsruhe, of the technical specifications and working - prototypes of the 'CONTAINMENT' module in the software package 'STEPS' (Source Term Estimation based on Plant Status). (author)

  1. Biological characteristics and clinical outcome of triple negative primary breast cancer in older women - comparison with their younger counterparts.

    Directory of Open Access Journals (Sweden)

    Binafsha M Syed

    Full Text Available Triple negative (ER, PgR and HER2 negative breast cancers (TNBCs are often considered as a poor prognostic phenotype. There is dearth of evidence showing the prevalence and biological behaviour of TNBCs in older women. This study aimed to analyse their biological characteristics in comparison with a well characterised younger series from a single centre with long term clinical follow-up. Over 37 years (1973-2010, 1,758 older (≥70 years women with early operable (<5 cm primary breast cancer were managed in a dedicated clinic and have complete clinical information available. Of these 813 patients underwent primary surgery and 575 had good quality tumour samples available for tissue microarray analysis using indirect immunohistochemistry. A total of 127 patients (22.1% had TNBCs and full biological analysis of 15 biomarkers was performed. The results were compared with those of their younger (<70 years counterparts 342 (18.9% from a previously characterised, consecutive series of primary breast cancer treated in the same unit (1986-1998. The 127 older patients with TNBCs showed lower rates of Ki67 and CK 7/8 positivity and high rates of bcl2 and CK18 positivity when compared with their younger counterparts (p<0.05. There was no significant difference in the long term clinical outcome between the two age groups, despite the fact that 47% of the younger patients had adjuvant chemotherapy, while none in the older cohort received such treatment. EGFR, axillary stage and pathological size showed prognostic significance in older women with TNBCs on univariate analysis. Despite not having received adjuvant chemotherapy, the older series had clinical outcome similar to the younger patients almost half of whom had chemotherapy. This appears to be related to other biomarkers (in addition to ER/PgR/HER2 eg Ki67, bcl2 and cytokeratins which have different expression patterns influencing prognosis.

  2. The Discovery of the Electromagnetic Counterpart of GW170817: Kilonova AT 2017gfo/DLT17ck

    Science.gov (United States)

    Valenti, Stefano; David; Sand, J.; Yang, Sheng; Cappellaro, Enrico; Tartaglia, Leonardo; Corsi, Alessandra; Jha, Saurabh W.; Reichart, Daniel E.; Haislip, Joshua; Kouprianov, Vladimir

    2017-10-01

    During the second observing run of the Laser Interferometer Gravitational-wave Observatory (LIGO) and Virgo Interferometer, a gravitational-wave signal consistent with a binary neutron star coalescence was detected on 2017 August 17th (GW170817), quickly followed by a coincident short gamma-ray burst trigger detected by the Fermi satellite. The Distance Less Than 40 (DLT40) Mpc supernova search performed pointed follow-up observations of a sample of galaxies regularly monitored by the survey that fell within the combined LIGO+Virgo localization region and the larger Fermi gamma-ray burst error box. Here we report the discovery of a new optical transient (DLT17ck, also known as SSS17a; it has also been registered as AT 2017gfo) spatially and temporally coincident with GW170817. The photometric and spectroscopic evolution of DLT17ck is unique, with an absolute peak magnitude of M r = -15.8 ± 0.1 and an r-band decline rate of 1.1 mag day-1. This fast evolution is generically consistent with kilonova models, which have been predicted as the optical counterpart to binary neutron star coalescences. Analysis of archival DLT40 data does not show any sign of transient activity at the location of DLT17ck down to r ˜ 19 mag in the time period between 8 months and 21 days prior to GW170817. This discovery represents the beginning of a new era for multi-messenger astronomy, opening a new path by which to study and understand binary neutron star coalescences, short gamma-ray bursts, and their optical counterparts.

  3. The Discovery of the Electromagnetic Counterpart of GW170817: Kilonova AT 2017gfo/DLT17ck

    Energy Technology Data Exchange (ETDEWEB)

    Valenti, Stefano; Yang, Sheng; Tartaglia, Leonardo [Department of Physics, University of California, 1 Shields Avenue, Davis, CA 95616-5270 (United States); Sand, David J. [Department of Astronomy/Steward Observatory, 933 North Cherry Avenue, Room N204, Tucson, AZ 85721-0065 (United States); Cappellaro, Enrico [INAF Osservatorio Astronomico di Padova, Vicolo dell’Osservatorio 5, I-35122 Padova (Italy); Corsi, Alessandra [Physics and Astronomy Department, Texas Tech University, Lubbock, TX 79409 (United States); Jha, Saurabh W. [Department of Physics and Astronomy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 (United States); Reichart, Daniel E.; Haislip, Joshua; Kouprianov, Vladimir [Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (United States)

    2017-10-20

    During the second observing run of the Laser Interferometer Gravitational-wave Observatory (LIGO) and Virgo Interferometer, a gravitational-wave signal consistent with a binary neutron star coalescence was detected on 2017 August 17th (GW170817), quickly followed by a coincident short gamma-ray burst trigger detected by the Fermi satellite. The Distance Less Than 40 (DLT40) Mpc supernova search performed pointed follow-up observations of a sample of galaxies regularly monitored by the survey that fell within the combined LIGO+Virgo localization region and the larger Fermi gamma-ray burst error box. Here we report the discovery of a new optical transient (DLT17ck, also known as SSS17a; it has also been registered as AT 2017gfo) spatially and temporally coincident with GW170817. The photometric and spectroscopic evolution of DLT17ck is unique, with an absolute peak magnitude of M {sub r} = −15.8 ± 0.1 and an r -band decline rate of 1.1 mag day{sup −1}. This fast evolution is generically consistent with kilonova models, which have been predicted as the optical counterpart to binary neutron star coalescences. Analysis of archival DLT40 data does not show any sign of transient activity at the location of DLT17ck down to r ∼ 19 mag in the time period between 8 months and 21 days prior to GW170817. This discovery represents the beginning of a new era for multi-messenger astronomy, opening a new path by which to study and understand binary neutron star coalescences, short gamma-ray bursts, and their optical counterparts.

  4. Two specific membrane-bound aminopeptidase N isoforms from Aedes aegypti larvae serve as functional receptors for the Bacillus thuringiensis Cry4Ba toxin implicating counterpart specificity.

    Science.gov (United States)

    Aroonkesorn, Aratee; Pootanakit, Kusol; Katzenmeier, Gerd; Angsuthanasombat, Chanan

    2015-05-29

    The interaction between Bacillus thuringiensis Cry toxins and their receptors on midgut cells of susceptible insect larvae is the critical determinant in toxin specificity. Besides GPI-linked alkaline phosphatase in Aedes aegypti mosquito-larval midguts, membrane-bound aminopeptidase N (AaeAPN) is widely thought to serve as a Cry4Ba receptor. Here, two full-length AaeAPN isoforms, AaeAPN2778 and AaeAPN2783, predicted to be GPI-linked were cloned and successfully expressed in Spodoptera frugiperda (Sf9) cells as 112- and 107-kDa membrane-bound proteins, respectively. In the cytotoxicity assay, Sf9 cells expressing each of the two AaeAPN isoforms showed increased sensitivity to the Cry4Ba mosquito-active toxin. Double immunolocalization revealed specific binding of Cry4Ba to each individual AaeAPN expressed on the cell membrane surface. Sequence analysis and homology-based modeling placed these two AaeAPNs to the M1 aminopeptidase family as they showed similar four-domain structures, with the most conserved domain II being the catalytic component. Additionally, the most variable domain IV containing negatively charged surface patches observed only in dipteran APNs could be involved in insect specificity. Overall results demonstrated that these two membrane-bound APN isoforms were responsible for mediating Cry4Ba toxicity against AaeAPN-expressed Sf9 cells, suggesting their important role as functional receptors for the toxin counterpart in A. aegypti mosquito larvae. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. First report on the gastropod proapoptotic AIF3 counterpart from disk abalone (Haliotis discus discus) deciphering its transcriptional modulation by induced pathogenic stress.

    Science.gov (United States)

    Elvitigala, Don Anushka Sandaruwan; Jayasooriya, R G P T; Whang, Ilson; Lee, Jehee

    2015-12-01

    Apoptosis inducing factor (AIF) is a flavoprotein that is involved in oxidative phosphorylation and induces apoptosis in eukaryotic cells. There are three isozymes of AIF that have been identified to date, designated as AIF1, AIF2, and AIF3; the human AIF3 is also known as an AIF-like protein (AIFL). This study aimed to identify and characterize a homologue of AIF3 from disk abalone (AbAIF3) that belongs to the phylum Mollusca. The open reading frame (ORF) of AbAIF3 is 1749 base pairs (bp) in length and encodes a protein of 583 amino acids, with a predicted molecular mass of 63.14 kDa. Based on our in-silico analysis, the AbAIF3 protein harbored the typical domain architecture as that of the known AIF family proteins, consisting of N-terminal Rieske and pyridine nucleotide-disulphide oxidoreductase domain. Comparative protein sequence analysis confirmed that AbAIF3 is a homolog of AIF3. Moreover, our phylogenetic analysis revealed that AbAIF3 had a close evolutionary relationship with the molluscan counterparts. Interestingly, AbAIF3 was shown to induce apoptosis in HEK293T cells using transfection assays followed by flow cytometric analysis. In addition, we found that AbAIF3 mRNA expression was ubiquitous in physiologically important tissues, and significantly modulated upon experimental immune stimulations in hemocytes. Collectively, our study illustrates the indispensable role of AbAIF3 in inducing apoptosis in disk abalones, which in turn might be involved in hosts' immune defense mechanisms against microbial infections. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. The isolated neutron star RBS1774 revisited. Revised XMM-Newton X-ray parameters and an optical counterpart from deep LBT-observations

    Science.gov (United States)

    Schwope, A. D.; Erben, T.; Kohnert, J.; Lamer, G.; Steinmetz, M.; Strassmeier, K.; Zinnecker, H.; Bechtold, J.; Diolaiti, E.; Fontana, A.; Gallozzi, S.; Giallongo, E.; Ragazzoni, R.; de Santis, C.; Testa, V.

    2009-05-01

    We report optical B-band observations with the Large Binocular Telescope (LBT) of the isolated neutron star RBS1774. The stacked image with a total exposure of 2fh5 reveals a candidate optical counterpart at mB = 26.96 ± 0.20 at position α (2000) = 21^h43^m03fs40, δ(2000) = +06degr54^prime17farcs5, within the joint Chandra and XMM-Newton error circles. We analyse archival XMM-Newton observations and derive revised spectral and positional parameters. The predicted optical flux from the extrapolated X-ray spectrum is likely twice as high as reported before. The measured optical flux exceeds the extrapolated X-ray spectral flux by a factor ˜40 (15-60 at 1σ confidence). We interpret our detection and the spectral energy distribution as further evidence of a temperature structure over the neutron star's surface and present a pure thermal model reflecting both the SED and the pulsed fraction of the light curve. Based on observations obtained with XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA Member States and NASA. Based on data acquired using the Large Binocular Telescope (LBT). The LBT is an international collaboration among institutions in the US, Italy, and Germany. LBT Corporation partners are the University of Arizona, on behalf of the Arizona university system; Istituto Nazionale di Astrofisica, Italy; LBT Beteiligungsgesellschaft, Germany, representing the Max Planck Society, the Astrophysical Institute Potsdam, and Heidelberg University; Ohio State University; and the Research Corporation, on behalf of the University of Notre Dame, the University of Minnesota, and the University of Virginia.

  7. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. III. Optical and UV Spectra of a Blue Kilonova from Fast Polar Ejecta

    Energy Technology Data Exchange (ETDEWEB)

    Nicholl, M.; Berger, E.; Kasen, D.; Metzger, B. D.; Elias, J.; Briceño, C.; Alexander, K. D.; Blanchard, P. K.; Chornock, R.; Cowperthwaite, P. S.; Eftekhari, T.; Fong, W.; Margutti, R.; Villar, V. A.; Williams, P. K. G.; Brown, W.; Annis, J.; Bahramian, A.; Brout, D.; Brown, D. A.; Chen, H. -Y.; Clemens, J. C.; Dennihy, E.; Dunlap, B.; Holz, D. E.; Marchesini, E.; Massaro, F.; Moskowitz, N.; Pelisoli, I.; Rest, A.; Ricci, F.; Sako, M.; Soares-Santos, M.; Strader, J.

    2017-10-16

    We present optical and ultraviolet spectra of the first electromagnetic counterpart to a gravitational wave (GW) source, the binary neutron star merger GW170817. Spectra were obtained nightly between 1.5 and 9.5 days post-merger, using the SOAR and Magellan telescopes; the UV spectrum was obtained with the \\textit{Hubble Space Telescope} at 5.5 days. Our data reveal a rapidly-fading blue component ($T\\approx5500$ K at 1.5 days) that quickly reddens; spectra later than $\\gtrsim 4.5$ days peak beyond the optical regime. The spectra are mostly featureless, although we identify a possible weak emission line at $\\sim 7900$ \\AA\\ at $t\\lesssim 4.5$ days. The colours, rapid evolution and featureless spectrum are consistent with a "blue" kilonova from polar ejecta comprised mainly of light $r$-process nuclei with atomic mass number $A\\lesssim 140$. This indicates a sight-line within $\\theta_{\\rm obs}\\lesssim 45^{\\circ}$ of the orbital axis. Comparison to models suggests $\\sim0.03$ M$_\\odot$ of blue ejecta, with a velocity of $\\sim 0.3c$. The required lanthanide fraction is $\\sim 10^{-4}$, but this drops to $<10^{-5}$ in the outermost ejecta. The large velocities point to a dynamical origin, rather than a disk wind, for this blue component, suggesting that both binary constituents are neutron stars (as opposed to a binary consisting of a neutron star and a black hole). For dynamical ejecta, the high mass favors a small neutron star radius of $\\lesssim 12$ km. This mass also supports the idea that neutron star mergers are a major contributor to $r$-process nucleosynthesis.

  8. Kilonova from post-merger ejecta as an optical and near-Infrared counterpart of GW170817

    Science.gov (United States)

    Tanaka, Masaomi; Utsumi, Yousuke; Mazzali, Paolo A.; Tominaga, Nozomu; Yoshida, Michitoshi; Sekiguchi, Yuichiro; Morokuma, Tomoki; Motohara, Kentaro; Ohta, Kouji; Kawabata, Koji S.; Abe, Fumio; Aoki, Kentaro; Asakura, Yuichiro; Baar, Stefan; Barway, Sudhanshu; Bond, Ian A.; Doi, Mamoru; Fujiyoshi, Takuya; Furusawa, Hisanori; Honda, Satoshi; Itoh, Yoichi; Kawabata, Miho; Kawai, Nobuyuki; Kim, Ji Hoon; Lee, Chien-Hsiu; Miyazaki, Shota; Morihana, Kumiko; Nagashima, Hiroki; Nagayama, Takahiro; Nakaoka, Tatsuya; Nakata, Fumiaki; Ohsawa, Ryou; Ohshima, Tomohito; Okita, Hirofumi; Saito, Tomoki; Sumi, Takahiro; Tajitsu, Akito; Takahashi, Jun; Takayama, Masaki; Tamura, Yoichi; Tanaka, Ichi; Terai, Tsuyoshi; Tristram, Paul J.; Yasuda, Naoki; Zenko, Tetsuya

    2017-12-01

    Recent detection of gravitational waves from a neutron star (NS) merger event GW170817 and identification of an electromagnetic counterpart provide a unique opportunity to study the physical processes in NS mergers. To derive properties of ejected material from the NS merger, we perform radiative transfer simulations of kilonova, optical and near-infrared emissions powered by radioactive decays of r-process nuclei synthesized in the merger. We find that the observed near-infrared emission lasting for >10 d is explained by 0.03 M⊙ of ejecta containing lanthanide elements. However, the blue optical component observed at the initial phases requires an ejecta component with a relatively high electron fraction (Ye). We show that both optical and near-infrared emissions are simultaneously reproduced by the ejecta with a medium Ye of ˜0.25. We suggest that a dominant component powering the emission is post-merger ejecta, which exhibits that the mass ejection after the first dynamical ejection is quite efficient. Our results indicate that NS mergers synthesize a wide range of r-process elements and strengthen the hypothesis that NS mergers are the origin of r-process elements in the Universe.

  9. TOWARD UNDERSTANDING THE B[e] PHENOMENON. III. PROPERTIES OF THE OPTICAL COUNTERPART OF IRAS 00470+6429

    International Nuclear Information System (INIS)

    Miroshnichenko, A. S.; Chentsov, E. L.; Klochkova, V. G.; Zharikov, S. V.; Grankin, K. N.; Kusakin, A. V.; Gandet, T. L.; Klingenberg, G.; Kildahl, S.; Rudy, R. J.; Lynch, D. K.; Venturini, C. C.; Mazuk, S.; Puetter, R. C.; Perry, R. B.; Carciofi, A. C.; Bjorkman, K. S.; Gray, R. O.; Bernabei, S.; Polcaro, V. F.

    2009-01-01

    FS CMa type stars are a group of Galactic objects with the B[e] phenomenon. They exhibit strong emission-line spectra and infrared excesses, which are most likely due to recently formed circumstellar dust. The group content and identification criteria were described in the first two papers of the series. In this paper we report our spectroscopic and photometric observations of the optical counterpart of IRAS 00470+6429 obtained in 2003-2008. The optical spectrum is dominated by emission lines, most of which have P Cyg type profiles. We detected significant brightness variations, which may include a regular component, and variable spectral line profiles in both shape and position. The presence of a weak Li I 6708 A line in the spectrum suggests that the object is most likely a binary system with a B2-B3 spectral-type primary companion of a luminosity log L/L sun = 3.9 ± 0.3 and a late-type secondary companion. We estimate a distance toward the object to be 2.0 ± 0.3 kpc from the Sun.

  10. Hubble Space Telescope observations of the optical counterpart to a ultra-compact high-velocity cloud

    Science.gov (United States)

    Sand, David J.

    2017-01-01

    As part of a comprehensive archival search for optical counterparts to ultra-compact high-velocity clouds (UCHVCs), our team has uncovered five Local Volume dwarf galaxies, two of which were not previously known. Among these was AGC 226067, also known as ALFALFA-Dw1, which appeared to be made up of several HI and blue optical clumps based on ground-based data, with at least one HII region. Here we present Hubble Space Telescope Advanced Camera for Surveys data of AGC 226067. The data show that AGC 226067 is made up of a ~7-30 Myr old stellar population with a [Fe/H]~-0.6. Further, there is no evidence for an old stellar population associated with the system, down to a limit of MV>-8. Based on this and the position of AGC 226067 in the outskirts of the M86 subgroup of the Virgo cluster we present various arguments for the origin of this strange stellar system.

  11. A Dark Energy Camera Search for an Optical Counterpart to the First Advanced LIGO Gravitational Wave Event GW150914

    Science.gov (United States)

    Soares-Santos, M.; Kessler, R.; Burger, E.; Annis, J.; Brout, D.; Buckley-Geer, E.; Chen, H.; Cowperthwaite, P. S.; Diehl, H.T.; Doctor, Z.; hide

    2016-01-01

    We report the results of a deep search for an optical counterpart to the gravitational wave (GW) event GW150914, the first trigger from the Advanced LIGO GW detectors. We used the Dark Energy Camera (DECam) to image a 102 deg(exp 2) area, corresponding to 38% of the initial trigger high-probability sky region and to 11% of the revised high-probability region. We observed in the i and z bands at 4-5, 7, and 24 days after the trigger. The median 5(sigma) point-source limiting magnitudes of our search images are i = 22.5 and z = 21.8 mag. We processed the images through a difference-imaging pipeline using templates from pre-existing Dark Energy Survey data and publicly available DECam data. Due to missing template observations and other losses, our effective search area subtends 40 deg(exp 2), corresponding to a 12% total probability in the initial map and 3% in the final map. In this area, we search for objects that decline significantly between days 4-5 and day 7, and are undetectable by day 24, finding none to typical magnitude limits of i = 21.5, 21.1, 20.1 for object colors (i-z)= 1, 0, -1, respectively. Our search demonstrates the feasibility of a dedicated search program with DECam and bodes well for future research in this emerging field.

  12. Thermodynamic Stability of Ice II and Its Hydrogen-Disordered Counterpart: Role of Zero-Point Energy.

    Science.gov (United States)

    Nakamura, Tatsuya; Matsumoto, Masakazu; Yagasaki, Takuma; Tanaka, Hideki

    2016-03-03

    We investigate why no hydrogen-disordered form of ice II has been found in nature despite the fact that most of hydrogen-ordered ices have hydrogen-disordered counterparts. The thermodynamic stability of a set of hydrogen-ordered ice II variants relative to ice II is evaluated theoretically. It is found that ice II is more stable than the disordered variants so generated as to satisfy the simple ice rule due to the lower zero-point energy as well as the pair interaction energy. The residual entropy of the disordered ice II phase gradually compensates the unfavorable free energy with increasing temperature. The crossover, however, occurs at a high temperature well above the melting point of ice III. Consequently, the hydrogen-disordered phase does not exist in nature. The thermodynamic stability of partially hydrogen-disordered ices is also scrutinized by examining the free-energy components of several variants obtained by systematic inversion of OH directions in ice II. The potential energy of one variant is lower than that of the ice II structure, but its Gibbs free energy is slightly higher than that of ice II due to the zero-point energy. The slight difference in the thermodynamic stability leaves the possibility of the partial hydrogen-disorder in real ice II.

  13. UNVEILING THE NATURE OF THE UNIDENTIFIED GAMMA-RAY SOURCES. III. GAMMA-RAY BLAZAR-LIKE COUNTERPARTS AT LOW RADIO FREQUENCIES

    Energy Technology Data Exchange (ETDEWEB)

    Massaro, F.; Funk, S. [SLAC National Laboratory and Kavli Institute for Particle Astrophysics and Cosmology, 2575 Sand Hill Road, Menlo Park, CA 94025 (United States); D' Abrusco, R.; Paggi, A. [Harvard-Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Giroletti, M. [INAF Istituto di Radioastronomia, via Gobetti 101, I-40129 Bologna (Italy); Masetti, N. [INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica di Bologna, via Gobetti 101, I-40129 Bologna (Italy); Tosti, G. [Dipartimento di Fisica, Universita degli Studi di Perugia, I-06123 Perugia (Italy); Nori, M. [Department of Physics and Astronomy, University of Bologna, viale Berti Pichat 6/2, I-40127 Bologna (Italy)

    2013-07-01

    About one-third of the {gamma}-ray sources listed in the second Fermi Large Area Telescope catalog (2FGL) have no firmly established counterpart at lower energies and so are classified as unidentified gamma-ray sources (UGSs). Here, we propose a new approach to find candidate counterparts for the UGSs based on the 325 MHz radio survey performed with the Westerbork Synthesis Radio Telescope in the northern hemisphere. First, we investigate the low-frequency radio properties of blazars, the largest known population of {gamma}-ray sources; then we search for sources with similar radio properties combining the information derived from the Westerbork Northern Sky Survey (WENSS) with those of the NRAO Very Large Array Sky Survey. We present a list of candidate counterparts for 32 UGSs with at least one counterpart in the WENSS. We also performed an extensive research in the literature to look for infrared and optical counterparts of the {gamma}-ray blazar candidates selected using the low-frequency radio observations to confirm their nature. On the basis of our multifrequency research, we identify 23 new {gamma}-ray blazar candidates out of the 32 UGSs investigated. Comparison with previous results on the UGSs is also presented. Finally, we speculate on the advantages of using low-frequency radio observations to associate UGSs and to search for {gamma}-ray pulsar candidates.

  14. First-principles study of SO2 sensors based on phosphorene and its isoelectronic counterparts: GeS, GeSe, SnS, SnSe

    Science.gov (United States)

    Guo, Shiying; Yuan, Lu; Liu, Xuhai; Zhou, Wenhan; Song, Xiufeng; Zhang, Shengli

    2017-10-01

    Phosphorene and its isoelectronic counterparts, such as GeS, GeSe, SnS and SnSe monolayers, show great potential in electrical and sensing applications. Here, we study the SO2 sensing properties of phosphorene and its isoelectronic counterparts by first-principles calculations. Results predict that the SO2 molecule as electron acceptor holds high adsorption strength with the five monolayer substrates, especially for SnS and SnSe monolayers. Moreover, the electronic properties of the five substrates can be modified by the SO2 molecule, together with distinct charge transfer, rendering them promising for application as a high-performance gas sensor.

  15. Definition of the Cattle Killer Cell Ig–like Receptor Gene Family: Comparison with Aurochs and Human Counterparts

    Science.gov (United States)

    Sanderson, Nicholas D.; Norman, Paul J.; Guethlein, Lisbeth A.; Ellis, Shirley A.; Williams, Christina; Breen, Matthew; Park, Steven D. E.; Magee, David A.; Babrzadeh, Farbod; Warry, Andrew; Watson, Mick; Bradley, Daniel G.; MacHugh, David E.; Parham, Peter

    2014-01-01

    Under selection pressure from pathogens, variable NK cell receptors that recognize polymorphic MHC class I evolved convergently in different species of placental mammal. Unexpectedly, diversified killer cell Ig–like receptors (KIRs) are shared by simian primates, including humans, and cattle, but not by other species. Whereas much is known of human KIR genetics and genomics, knowledge of cattle KIR is limited to nine cDNA sequences. To facilitate comparison of the cattle and human KIR gene families, we determined the genomic location, structure, and sequence of two cattle KIR haplotypes and defined KIR sequences of aurochs, the extinct wild ancestor of domestic cattle. Larger than its human counterpart, the cattle KIR locus evolved through successive duplications of a block containing ancestral KIR3DL and KIR3DX genes that existed before placental mammals. Comparison of two cattle KIR haplotypes and aurochs KIR show the KIR are polymorphic and the gene organization and content appear conserved. Of 18 genes, 8 are functional and 10 were inactivated by point mutation. Selective inactivation of KIR3DL and activating receptor genes leaves a functional cohort of one inhibitory KIR3DL, one activating KIR3DX, and six inhibitory KIR3DX. Functional KIR diversity evolved from KIR3DX in cattle and from KIR3DL in simian primates. Although independently evolved, cattle and human KIR gene families share important function-related properties, indicating that cattle KIR are NK cell receptors for cattle MHC class I. Combinations of KIR and MHC class I are the major genetic factors associated with human disease and merit investigation in cattle. PMID:25398326

  16. Paying for convenience: comparing the cost of takeaway meals with their healthier home-cooked counterparts in New Zealand.

    Science.gov (United States)

    Mackay, Sally; Vandevijvere, Stefanie; Xie, Pei; Lee, Amanda; Swinburn, Boyd

    2017-09-01

    Convenience and cost impact on people's meal decisions. Takeaway and pre-prepared foods save preparation time but may contribute to poorer-quality diets. Analysing the impact of time on relative cost differences between meals of varying convenience contributes to understanding the barrier of time to selecting healthy meals. Six popular New Zealand takeaway meals were identified from two large national surveys and compared with similar, but healthier, home-made and home-assembled meals that met nutrition targets consistent with New Zealand Eating and Activity Guidelines. The cost of each complete meal, cost per kilogram, and confidence intervals of the cost of each meal type were calculated. The time-inclusive cost was calculated by adding waiting or preparation time cost at the minimum wage. A large urban area in New Zealand. For five of six popular meals, the mean cost of the home-made and home-assembled meals was cheaper than the takeaway meals. When the cost of time was added, all home-assembled meal options were the cheapest and half of the home-made meals were at least as expensive as the takeaway meals. The home-prepared meals were designed to provide less saturated fat and Na and more vegetables than their takeaway counterparts; however, the home-assembled meals provided more Na than the home-made meals. Healthier home-made and home-assembled meals were, except one, cheaper options than takeaways. When the cost of time was added, either the home-made or the takeaway meal was the most expensive. This research questions whether takeaways are better value than home-prepared meals.

  17. Acetylcholinesterase immobilization and characterization, and comparison of the activity of the porous silicon-immobilized enzyme with its free counterpart

    Science.gov (United States)

    Saleem, Muhammad; Rafiq, Muhammad; Seo, Sung-Yum; Lee, Ki Hwan

    2016-01-01

    A successful prescription is presented for acetylcholinesterase physically adsorbed on to a mesoporous silicon surface, with a promising hydrolytic response towards acetylthiocholine iodide. The catalytic behaviour of the immobilized enzyme was assessed by spectrophotometric bioassay using neostigmine methyl sulfate as a standard acetycholinesterase inhibitor. The surface modification was studied through field emission SEM, Fourier transform IR spectroscopy, energy-dispersive X-ray spectroscopy, cathode luminescence and X-ray photoelectron spectroscopy analysis, photoluminescence measurement and spectrophotometric bioassay. The porous silicon-immobilized enzyme not only yielded greater enzyme stability, but also significantly improved the native photoluminescence at room temperature of the bare porous silicon architecture. The results indicated the promising catalytic behaviour of immobilized enzyme compared with that of its free counterpart, with a greater stability, and that it aided reusability and easy separation from the reaction mixture. The porous silicon-immobilized enzyme was found to retain 50% of its activity, promising thermal stability up to 90°C, reusability for up to three cycles, pH stability over a broad pH of 4–9 and a shelf-life of 44 days, with an optimal hydrolytic response towards acetylthiocholine iodide at variable drug concentrations. On the basis of these findings, it was believed that the porous silicon-immobilized enzyme could be exploited as a reusable biocatalyst and for screening of acetylcholinesterase inhibitors from crude plant extracts and synthesized organic compounds. Moreover, the immobilized enzyme could offer a great deal as a viable biocatalyst in bioprocessing for the chemical and pharmaceutical industries, and bioremediation to enhance productivity and robustness. PMID:26839417

  18. Overweight and obesity among Ghanaian residents in the Netherlands: How do they weigh against their urban and rural counterparts in Ghana?

    NARCIS (Netherlands)

    Agyemang, C.; Owusu-Dabo, E.; Jonge, A. de; Martins, D.; Ogedegbe, G.; Stronks, K.

    2009-01-01

    Objective: To investigate differences in overweight and obesity between first-generation Dutch-Ghanaian migrants in The Netherlands and their rural and urban counterparts in Ghana. Design: Cross-sectional study. Subjects: A total of 1471 Ghanaians (rural Ghanaians, n 532; urban Ghanaians, n 787;

  19. Overweight and obesity among Ghanaian residents in The Netherlands: how do they weigh against their urban and rural counterparts in Ghana?

    NARCIS (Netherlands)

    Agyemang, Charles; Owusu-Dabo, Ellis; de Jonge, Ank; Martins, David; Ogedegbe, Gbenga; Stronks, Karien

    2009-01-01

    OBJECTIVE: To investigate differences in overweight and obesity between first-generation Dutch-Ghanaian migrants in The Netherlands and their rural and urban counterparts in Ghana. DESIGN: Cross-sectional study. SUBJECTS: A total of 1471 Ghanaians (rural Ghanaians, n 532; urban Ghanaians, n 787;

  20. Comparison of Scores on the WAIS and Its Puerto Rican Counterpart, Escala de Inteligencia Wechsler para Adultos, in an Institutionalized Latin American Psychiatric Population.

    Science.gov (United States)

    Davis, Todd McLin; Rodriguez, Vene L.

    1979-01-01

    Compared vocabulary and block design subtests of the Wechsler Adult Intelligence Scale (WAIS) and its Puerto Rican counterpart, the Escala de Inteligencia Wechsler para Adultos (EIWA), in hospitalized Latins and Trans-Caribbean Blacks. EIWA scores were significantly higher than WAIS scores. Equivalence of EIWA and WAIS estimates is questioned.…

  1. The cost of blocking the mirror generalization process in reading: evidence for the role of inhibitory control in discriminating letters with lateral mirror-image counterparts.

    Science.gov (United States)

    Borst, Grégoire; Ahr, Emmanuel; Roell, Margot; Houdé, Olivier

    2015-02-01

    Mirror generalization is detrimental for identifying letters with lateral mirror-image counterparts ('b/d'). In the present study, we investigated whether the discrimination of this type of letters in expert readers might be rooted in the ability to inhibit the mirror-generalization process. In our negative priming paradigm, participants judged whether two letters were identical on the prime and two animals (or buildings) were identical on the probe. In Experiment 1, participants required more time when determining that two animals (but not two buildings) were mirror images of each other when preceded by letters with mirror-image counterparts than without mirror-image counterparts ('a/h'). In Experiment 2, we replicated the results with different letters without mirror-image counterparts and with the type of probe stimuli (animal or building) manipulated as a within-subject factors. Our results suggest that expert readers never completely "unlearn" the mirror-generalization process and still need to inhibit this heuristic to overcome mirror errors.

  2. Chicken embryonic stem cells and primordial germ cells display different heterochromatic histone marks than their mammalian counterparts.

    Science.gov (United States)

    Kress, Clémence; Montillet, Guillaume; Jean, Christian; Fuet, Aurélie; Pain, Bertrand

    2016-01-01

    differentiated chicken ESCs and embryonic fibroblasts, and DNMT3A was strongly expressed in ESCs, differentiated ESCs and BCs. Chicken ESCs and PGCs differ from their mammalian counterparts with respect to H3K27 methylation. High enrichment of H3K27me3 at PCH is specific to pluripotent cells in chicken. Our results demonstrate that the dynamics in chromatin constitution described during mouse development is not universal to all vertebrate species.

  3. Near-infrared diffuse interstellar bands in APOGEE telluric standard star spectra . Weak bands and comparisons with optical counterparts

    Science.gov (United States)

    Elyajouri, M.; Lallement, R.; Monreal-Ibero, A.; Capitanio, L.; Cox, N. L. J.

    2017-04-01

    Aims: Information on the existence and properties of diffuse interstellar bands (DIBs) outside the optical domain is still limited. Additional infra-red (IR) measurements and IR-optical correlative studies are needed to constrain DIB carriers and locate various absorbers in 3D maps of the interstellar matter. Methods: We extended our study of H-band DIBs in Apache Point Observatory Galactic Evolution Experiment (APOGEE) Telluric Standard Star (TSS) spectra. We used the strong λ15273 band to select the most and least absorbed targets. We used individual spectra of the former subsample to extract weaker DIBs, and we searched the two stacked series for differences that could indicate additional bands. High-resolution NARVAL and SOPHIE optical spectra for a subsample of 55 TSS targets were additionally recorded for NIR/optical correlative studies. Results: From the TSS spectra we extract a catalog of measurements of the poorly studied λλ15617, 15653, and 15673 DIBs in ≃300 sightlines, we obtain a first accurate determination of their rest wavelength and constrained their intrinsic width and shape. In addition, we studied the relationship between these weak bands and the strong λ15273 DIB. We provide a first or second confirmation of several other weak DIBs that have been proposed based on different instruments, and we add new constraints on their widths and locations. We finally propose two new DIB candidates. Conclusions: We compared the strength of the λ15273 absorptions with their optical counterparts λλ5780, 5797, 6196, 6283, and 6614. Using the 5797-5780 ratio as a tracer of shielding against the radiation field, we showed that the λ15273 DIB carrier is significantly more abundant in unshielded (σ-type) clouds, and it responds even more strongly than the λ5780 band carrier to the local ionizing field. Full Table 5 is available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc

  4. The Intestinal Mycobiota in Wild Zebrafish Comprises Mainly Dothideomycetes While Saccharomycetes Predominate in Their Laboratory-Reared Counterparts

    Directory of Open Access Journals (Sweden)

    Prabhugouda Siriyappagouder

    2018-03-01

    Full Text Available As an integral part of the resident microbial community of fish intestinal tract, the mycobiota is expected to play important roles in health and disease resistance of the host. The composition of the diverse fungal communities, which colonize the intestine, is greatly influenced by the host, their diet and geographic origin. Studies of fungal communities are rare and the majority of previous studies have relied on culture-based methods. In particular, fungal communities in fish are also poorly characterized. The aim of this study was to provide an in-depth overview of the intestinal mycobiota in a model fish species (zebrafish, Danio rerio and to determine differences in fungal composition between wild and captive specimens. We have profiled the intestinal mycobiota of wild-caught (Sharavati River, India, laboratory-reared (Bodø, Norway and wild-caught-laboratory-kept (Uttara, India zebrafish by sequencing the fungal internal transcribed spacer 2 region on the Illumina MiSeq platform. Wild fish were exposed to variable environmental factors, whereas both laboratory groups were kept in controlled conditions. There were also differences in husbandry practices at Bodø and Uttara, particularly diet. Zebrafish from Bodø were reared in the laboratory for over 10 generations, while wild-caught-laboratory-kept fish from Uttara were housed in the laboratory for only 2 months before sample collection. The intestine of zebrafish contained members of more than 15 fungal classes belonging to the phyla Ascomycota, Basidiomycota, and Zygomycota. Fungal species richness and diversity distinguished the wild-caught and laboratory-reared zebrafish communities. Wild-caught zebrafish-associated mycobiota comprised mainly Dothideomycetes in contrast to their Saccharomycetes-dominated laboratory-reared counterparts. The predominant Saccharomycetes in laboratory-reared fish belonged to the saprotrophic guild. Another characteristic feature of laboratory-reared fish

  5. ON Bipolar Cells in Macaque Retina: Type-Specific Synaptic Connectivity with Special Reference to OFF Counterparts

    Science.gov (United States)

    Tsukamoto, Yoshihiko; Omi, Naoko

    2016-01-01

    To date, 12 macaque bipolar cell types have been described. This list includes all morphology types first outlined by Polyak (1941) using the Golgi method in the primate retina and subsequently identified by other researchers using electron microscopy (EM) combined with the Golgi method, serial section transmission EM (SSTEM), and immunohistochemical imaging. We used SSTEM for the rod-dense perifoveal area of macaque retina, reconfirmed ON (cone) bipolar cells to be classified as invaginating midget bipolar (IMB), diffuse bipolar (DB)4, DB5, DB6, giant bipolar (GB), and blue bipolar (BB) types, and clarified their type-specific connectivity. DB4 cells made reciprocal synapses with a kind of ON-OFF lateral amacrine cell, similar to OFF DB2 cells. GB cells contacted rods and cones, similar to OFF DB3b cells. Retinal circuits formed by GB and DB3b cells are thought to substantiate the psychophysical finding of fast rod signals in mesopic vision. DB6 cell output synapses were directed to ON midget ganglion (MG) cells at 70% of ribbon contacts, similar to OFF DB1 cells that directed 60% of ribbon contacts to OFF MG cells. IMB cells contacted medium- or long-wavelength sensitive (M/L-) cones but not short-wavelength sensitive (S-) cones, while BB cells contacted S-cones but not M/L-cones. However, IMB and BB dendrites had similar morphological architectures, and a BB cell contacting a single S-cone resembled an IMB cell. Thus, both IMB and BB may be the ON bipolar counterparts of the OFF flat midget bipolar (FMB) type, likewise DB4 of DB2, DB5 of DB3a, DB6 of DB1, and GB of DB3b OFF bipolar type. The ON DB plus GB, and OFF DB cells predominantly contacted M/L-cones and their outputs were directed mainly to parasol ganglion (PG) cells but also moderately to MG cells. BB cells directed S-cone-driven outputs almost exclusively to small bistratified ganglion (SBG) cells. Some FMB cells predominantly contacted S-cones and their outputs were directed to OFF MG cells. Thus, two

  6. NEAR-INFRARED COUNTERPARTS TO CHANDRA X-RAY SOURCES TOWARD THE GALACTIC CENTER. I. STATISTICS AND A CATALOG OF CANDIDATES

    International Nuclear Information System (INIS)

    Mauerhan, J. C.; Muno, M. P.; Morris, M. R.; Bauer, F. E.; Nishiyama, S.; Nagata, T.

    2009-01-01

    We present a catalog of 5184 candidate infrared counterparts to X-ray sources detected toward the Galactic center. The X-ray sample contains 9017 point sources detected in this region by the Chandra X-ray Observatory during the past decade, including data from a recent deep survey of the central 2 0 x 0. 0 8 of the Galactic plane. A total of 6760 of these sources have hard X-ray colors, and the majority of them lie near the Galactic center, while most of the remaining 2257 soft X-ray sources lie in the foreground. We cross-correlated the X-ray source positions with the 2MASS and SIRIUS near-infrared catalogs, which collectively contain stars with a 10σ limiting flux of K s ≤ 15.6 mag. In order to distinguish absorbed infrared sources near the Galactic center from those in the foreground, we defined red and blue sources as those which have H - K s ≥ 0.9 and <0.9 mag, respectively. We find that 5.8% ± 1.5% (2σ) of the hard X-ray sources have real infrared counterparts, of which 228 ± 99 are red and 166 ± 27 are blue. The red counterparts are probably comprised of Wolf-Rayet and O stars, high-mass X-ray binaries, and symbiotic binaries located near the Galactic center. Foreground X-ray binaries suffering intrinsic X-ray absorption could be included in the sample of blue infrared counterparts to hard X-ray sources. We also find that 39.4% ± 1.0% of the soft X-ray sources have blue infrared counterparts; most of these are probably coronally active dwarfs in the foreground. There is a noteworthy collection of ∼20 red counterparts to hard X-ray sources near the Sagittarius B H II region, which are probably massive binaries that have formed within the last several Myr. For each of the infrared matches to X-ray sources in our catalog we derived the probability that the association is real, based on the source properties and the results of the cross-correlation analysis. These data are included in our catalog and will serve spectroscopic surveys to identify

  7. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. VIII. A Comparison to Cosmological Short-duration Gamma-Ray Bursts

    Science.gov (United States)

    Fong, W.; Berger, E.; Blanchard, P. K.; Margutti, R.; Cowperthwaite, P. S.; Chornock, R.; Alexander, K. D.; Metzger, B. D.; Villar, V. A.; Nicholl, M.; Eftekhari, T.; Williams, P. K. G.; Annis, J.; Brout, D.; Brown, D. A.; Chen, H.-Y.; Doctor, Z.; Diehl, H. T.; Holz, D. E.; Rest, A.; Sako, M.; Soares-Santos, M.

    2017-10-01

    We present a comprehensive comparison of the properties of the radio through X-ray counterpart of GW170817 and the properties of short-duration gamma-ray bursts (GRBs). For this effort, we utilize a sample of 36 short GRBs spanning a redshift range of z≈ 0.12{--}2.6 discovered over 2004-2017. We find that the counterpart to GW170817 has an isotropic-equivalent luminosity that is ≈ 3000 times less than the median value of on-axis short GRB X-ray afterglows, and ≳104 times less than that for detected short GRB radio afterglows. Moreover, the allowed jet energies and particle densities inferred from the radio and X-ray counterparts to GW170817 and on-axis short GRB afterglows are remarkably similar, suggesting that viewing angle effects are the dominant, and perhaps only, difference in their observed radio and X-ray behavior. From comparison to previous claimed kilonovae following short GRBs, we find that the optical and near-infrared (NIR) counterpart to GW170817 is comparatively under-luminous by a factor of ≈ 3{--}5, indicating a range of kilonova luminosities and timescales. A comparison of the optical limits following short GRBs on ≲ 1 day timescales also rules out a “blue” kilonova of comparable optical isotropic-equivalent luminosity in one previous short GRB. Finally, we investigate the host galaxy of GW170817, NGC 4993, in the context of short GRB host galaxy stellar population properties. We find that NGC 4993 is superlative in terms of its large luminosity, old stellar population age, and low star formation rate compared to previous short GRB hosts. Additional events within the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo volume will be crucial in delineating the properties of the host galaxies of neutron star-neutron star (NS-NS) mergers, and connecting them to their cosmological counterparts.

  8. Finding counterparts for all-sky X-ray surveys with NWAY: a Bayesian algorithm for cross-matching multiple catalogues

    Science.gov (United States)

    Salvato, M.; Buchner, J.; Budavári, T.; Dwelly, T.; Merloni, A.; Brusa, M.; Rau, A.; Fotopoulou, S.; Nandra, K.

    2018-02-01

    We release the AllWISE counterparts and Gaia matches to 106 573 and 17 665 X-ray sources detected in the ROSAT 2RXS and XMMSL2 surveys with |b| > 15°. These are the brightest X-ray sources in the sky, but their position uncertainties and the sparse multi-wavelength coverage until now rendered the identification of their counterparts a demanding task with uncertain results. New all-sky multi-wavelength surveys of sufficient depth, like AllWISE and Gaia, and a new Bayesian statistics based algorithm, NWAY, allow us, for the first time, to provide reliable counterpart associations. NWAY extends previous distance and sky density based association methods and, using one or more priors (e.g. colours, magnitudes), weights the probability that sources from two or more catalogues are simultaneously associated on the basis of their observable characteristics. Here, counterparts have been determined using a Wide-field Infrared Survey Explorer (WISE) colour-magnitude prior. A reference sample of 4524 XMM/Chandra and Swift X-ray sources demonstrates a reliability of ∼94.7 per cent (2RXS) and 97.4 per cent (XMMSL2). Combining our results with Chandra-COSMOS data, we propose a new separation between stars and AGN in the X-ray/WISE flux-magnitude plane, valid over six orders of magnitude. We also release the NWAY code and its user manual. NWAY was extensively tested with XMM-COSMOS data. Using two different sets of priors, we find an agreement of 96 per cent and 99 per cent with published Likelihood Ratio methods. Our results were achieved faster and without any follow-up visual inspection. With the advent of deep and wide area surveys in X-rays (e.g. SRG/eROSITA, Athena/WFI) and radio (ASKAP/EMU, LOFAR, APERTIF, etc.) NWAY will provide a powerful and reliable counterpart identification tool.

  9. Mechanism elucidation of the cis-trans isomerization of an azole ruthenium-nitrosyl complex and its osmium counterpart.

    Science.gov (United States)

    Gavriluta, Anatolie; Büchel, Gabriel E; Freitag, Leon; Novitchi, Ghenadie; Tommasino, Jean Bernard; Jeanneau, Erwann; Kuhn, Paul-Steffen; González, Leticia; Arion, Vladimir B; Luneau, Dominique

    2013-06-03

    mechanisms have been considered. The value for the activation energy found for the dissociative mechanism is in good agreement with experimental activation enthalpy. Electrochemical investigation provides further evidence for higher reactivity of ruthenium complexes compared to that of osmium counterparts and shows that intramolecular electron transfer reactions do not affect the isomerization process. A dissociative mechanism of cis↔trans isomerization has been proposed for both ruthenium and osmium complexes.

  10. Mechanism Elucidation of the cis–trans Isomerization of an Azole Ruthenium–Nitrosyl Complex and Its Osmium Counterpart

    Science.gov (United States)

    2013-01-01

    been considered. The value for the activation energy found for the dissociative mechanism is in good agreement with experimental activation enthalpy. Electrochemical investigation provides further evidence for higher reactivity of ruthenium complexes compared to that of osmium counterparts and shows that intramolecular electron transfer reactions do not affect the isomerization process. A dissociative mechanism of cis↔trans isomerization has been proposed for both ruthenium and osmium complexes. PMID:23675748

  11. Talking about a Christine Borland sculpture: effective empathy in contemporary anatomy art (and an emerging counterpart in medical training?).

    Science.gov (United States)

    Richardson, Craig; Borland, Christine

    2015-05-04

    This Introduction and interview discusses the poetical and empathic insights that are a key to the effectiveness of contemporary artist Christine Borland's practice and its relevance to the medical humanities, visual art research and medical students' training. It takes place in a context of intensive interest in reciprocity and conversation as well as expert exchange between the fields of Medicine and Contemporary Arts. The interview develops an understanding of medical research and the application of its historical resources and contemporary practice-based research in contemporary art gallery exhibitions. Artists tend not to follow prescriptive programmes towards new historical knowledge, however, a desire to form productive relationships between history and contemporary art practice does reveal practical advantages. Borland's research also includes investigations in anatomy, medical practices and conservation.

  12. Talking about a Christine Borland sculpture: effective empathy in contemporary anatomy art (and an emerging counterpart in medical training?)

    Science.gov (United States)

    Richardson, Craig; Borland, Christine

    2015-01-01

    This Introduction and interview discusses the poetical and empathic insights that are a key to the effectiveness of contemporary artist Christine Borland's practice and its relevance to the medical humanities, visual art research and medical students’ training. It takes place in a context of intensive interest in reciprocity and conversation as well as expert exchange between the fields of Medicine and Contemporary Arts. The interview develops an understanding of medical research and the application of its historical resources and contemporary practice-based research in contemporary art gallery exhibitions. Artists tend not to follow prescriptive programmes towards new historical knowledge, however, a desire to form productive relationships between history and contemporary art practice does reveal practical advantages. Borland's research also includes investigations in anatomy, medical practices and conservation. PMID:27630533

  13. Mediterranean, invasive, woody species grow larger than their less-invasive counterparts under potential global environmental change.

    Science.gov (United States)

    Erskine-Ogden, Jennifer; Grotkopp, Eva; Rejmánek, Marcel

    2016-04-01

    Revealing biological differences between invasive and noninvasive species is essential for predicting species' distribution changes with global environmental change. While most research has focused on differences between invasive and noninvasive species under favorable conditions using herbaceous species, invasive woody angiosperms are also of great ecological concern. Our study focused on how growth and allocation may change for invasive and noninvasive, mediterranean, woody angiosperms under future conditions caused by global change, specifically increased nitrogen deposition and drought. We tested how seedling functional traits differed between invasive and noninvasive woody angiosperms under different experimental conditions in a greenhouse setting. We compared growth rates and allocation patterns using two levels of soil nitrogen and three levels of watering. We also examined trait log response ratios to increases in nitrogen and increases in water. Our study sampled angiosperm trees and shrubs, incorporating congeneric/confamilial relationships through 13 phylogenetically controlled contrasts. Three functional traits were highly and positively associated with plant invasiveness for most conditions studied: seedling plant mass, leaf area, and height. Invasive species also had significantly higher root mass ratios at low water regardless of nitrogen input. Invasive and noninvasive species had similar log response ratios to increases in nitrogen and watering for studied traits. Mediterranean, woody, invasive species' larger mass, leaf area, and early height advantage under elevated nitrogen input and increased root production in drought conditions may lead to increased invasion of these species with expected global climate change. © 2016 Botanical Society of America.

  14. Leveling the Playing Field: Assessment of Gross Motor Skills in Low Socioeconomic Children to their Higher Socioeconomic Counterparts

    Directory of Open Access Journals (Sweden)

    Megan M. Adkins

    2017-07-01

    Full Text Available Background: Fundamental movements (FM of children influence the willingness to engage in physical activity (PA. Thus, proper FM skills are the foundation for a lifespan of PA. Objective: This study examined what factors may affect children’s PA in relation to FM pattern capabilities. Methods: The study examined the influence of SES when three low-income schools were provided additional PA opportunities on days PE was not taught. FM patterns in relation to object control (OC and locomotor skill (LC development were evaluated on K (n = 871, 1st (n = 893, and 2nd graders (n = 829 using the Test of Gross Motor Development-2 (TGMD-2 instrument (Ulrich, 2000. Schools were dichotomized and categorized as being low SES (n = 2008 and high SES (n = 578 status. Results: A significant relationship was revealed with LC (r = 0.264; p = 0.001, OC (r = 0.171; p = 0.001, and total TGMD-2 (r = 0.264; p = 0.001. Low and high SES schools significantly improved overall TGMD-2 scores. High SES schools children were significantly higher in LC [F, (2, 1272 = 29.31, p = 0.001], OC [F, (2, 1272 = 23.14, p = 0.001], and total TGMD-2 [F, (1, 1272 = 38.11, p = 0.001]. Conclusion: Low SES schools need to concentrate on PA-based activities to engage students in FM patterns, to help narrow the gap in FM capabilities. In addition, the increase in PA opportunities for lower SES schools could positively impact brain function, cardiovascular fitness, and overall well-being.

  15. Real-Time Optical Flux Limits from Gamma-Ray Bursts Measured by the Gamma-Ray Optical Counterpart Search Experiment

    Science.gov (United States)

    Park, H. S. (Editor); Ables, E. (Editor); Band, D. L. (Editor); Barthelmy, S. D. (Editor); Bionta, R. M. (Editor); Butterworth, P. S. (Editor); Cline, T. L. (Editor); Ferguson, D. H. (Editor); Fishman, G. J. (Editor); Gehrels, N. (Editor); hide

    1997-01-01

    The Gamma-Ray Optical Counterpart Search Experiment presents new experimental upper limits on the optical flux from gamma-ray bursts (GRBs). Our experiment consisted of a fully automated very wide-field opto-electronic detection system that imaged locations of GRBs within a few seconds of receiving trigger signals provided by BATSE's real-time burst coordinate distribution network. The experiment acquired 3800 observing hours, recording 22 gamma-ray burst triggers within approx. 30 s of the start of the burst event. Some of these bursts were imaged while gamma-ray radiation was being detected by BATSE. We identified no optical counterparts associated with gamma-ray bursts among these events at the mV approx. 7.0-8.3 sensitivity level. We find the ratio of the upper limit to the V-band optical flux, F nu, to the gamma-ray fluence, Phi gamma, from these data to be 1 x 10(exp-18) less than F nu Phi gamma less than 2 x 10(exp -16).

  16. Inverse Compton Scattered Merger-nova: Late X-Ray Counterpart of Gravitational-wave Signals from NS–NS/BH Mergers

    Science.gov (United States)

    Ai, Shunke; Gao, He

    2018-01-01

    The recent observations of GW170817 and its electromagnetic (EM) counterparts show that double neutron star mergers could lead to rich and bright EM emissions. Recent numerical simulations suggest that neutron star and neutron star/black hole (NS–NS/BH) mergers would leave behind a central remnant surrounded by a mildly isotropic ejecta. The central remnant could launch a collimated jet and when the jet propagates through the ejecta, a mildly relativistic cocoon would be formed and the interaction between the cocoon and the ambient medium would accelerate electrons via external shock in a wide angle, so that the merger-nova photons (i.e., thermal emission from the ejecta) would be scattered into higher frequency via an inverse Compton (IC) process when they propagate through the cocoon shocked region. We find that the IC scattered component peaks at the X-ray band and it will reach its peak luminosity on the order of days (simultaneously with the merger-nova emission). With current X-ray detectors, such a late X-ray component could be detected out to 200 Mpc, depending on the merger remnant properties. It could serve as an important electromagnetic counterpart of gravitational-wave signals from NS–NS/BH mergers. Nevertheless, simultaneous detection of such a late X-ray signal and the merger-nova signal could shed light on the cocoon properties and the concrete structure of the jet.

  17. Molecular alterations in lesions of anogenital mammary-like glands and their mammary counterparts including hidradenoma papilliferum, intraductal papilloma, fibroadenoma and phyllodes tumor.

    Science.gov (United States)

    Konstantinova, Anastasia M; Vanecek, Tomas; Martinek, Petr; Kyrpychova, Liubov; Spagnolo, Dominic V; Stewart, Colin J R; Portelli, Francesca; Michal, Michal; Kazakov, Dmitry V

    2017-06-01

    Lesions affecting anogenital mammary-like glands (AGMLG) are histopathologically very similar to those seen in the breast but whether this morphological similarity is also reflected at the genetic level is unknown. To compare the underlying molecular mechanisms in lesions of AGMLG and their mammary counterparts, we analyzed the mutational profile of 16 anogenital neoplasms including 5 hidradenomas papilliferum (HP), 1 lesion with features of HP and fibroadenoma (FA), 7 FA, 3 phyllodes tumors (PhT)) and 18 analogous breast lesions (6 intraductal papillomas (IDP), 9 FA, and 3 PhT) by high-coverage next generation sequencing (NGS) using a panel comprising 50 cancer-related genes. Additionally, all cases were analyzed for the presence of a mutation in the MED12 gene. All detected mutations with allele frequencies over 20% were independently validated by Sanger sequencing (concordance: 100%). Mutations in PIK3CA, AKT1, MET, ABL1 and TP53 genes were found in lesions of AGMLG and also their mammary counterparts. The PI3K-AKT cascade plays a role in tumors arising at both sites. It appears that some histopathologically similar anogenital and breast lesions develop along similar molecular pathways. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Comparison of visual working memory in deaf and hearing-impaired students with normal counterparts: A research in people without sign language

    Directory of Open Access Journals (Sweden)

    Farideh Tangestani Zadeh

    2015-02-01

    Full Text Available Background and Aim: The hearing defects in deaf and hearing-impaired students also affect their cognitive skills such as memory in addition to communication skills. Hence, the aim of this study was to compare visual working memory in deaf and hearing-impaired students with that in normal counterparts.Method: In the present study, which was a causal-comparative study using the André Rey test, 30 deaf and 30 hearing-impaired students were compared with 30 students in a normal group, and they were matched based on gender, intelligence, educational grade, and socioeconomic status.Findings: Findings show that there is significant difference between the three groups’ subjects (p0.05.Conclusion: Function of deaf or hard-of-hearing students in the visual working memory task was weaker in comparison with the normal counterparts, while the two deaf and hard-of-hearing groups have similar functions. With a better identification and understanding of the factors that affect the development of this cognitive ability, we can offer new methods of teaching and reduce many of the disadvantages of this group of people in the different fields of cognitive science.

  19. Discovery of the near-infrared counterpart to the luminous neutron-star low-mass X-ray binary GX 3+1

    Energy Technology Data Exchange (ETDEWEB)

    Van den Berg, Maureen; Fridriksson, Joel K. [Anton Pannekoek Institute for Astronomy, University of Amsterdam, Science Park 904, 1098 XH Amsterdam (Netherlands); Homan, Jeroen [Massachusetts Institute of Technology, Kavli Institute for Astrophysics and Space Research, 70 Vassar Street, Cambridge, MA 02139 (United States); Linares, Manuel, E-mail: M.C.vandenBerg@uva.nl [Instituto de Astrofísica de Canarias (IAC), Vía Láctea s/n, La Laguna, E-38205, S/C de Tenerife (Spain)

    2014-10-01

    Using the High Resolution Camera on board the Chandra X-ray Observatory, we have measured an accurate position for the bright persistent neutron star X-ray binary and atoll source GX 3+1. At a location that is consistent with this new position, we have discovered the near-infrared (NIR) counterpart to GX 3+1 in images taken with the PANIC and FourStar cameras on the Magellan Baade Telescope. The identification of this K{sub s} = 15.8 ± 0.1 mag star as the counterpart is based on the presence of a Br γ emission line in an NIR spectrum taken with the Folded-port InfraRed Echelette spectrograph on the Baade Telescope. The absolute magnitude derived from the best available distance estimate to GX 3+1 indicates that the mass donor in the system is not a late-type giant. We find that the NIR light in GX 3+1 is likely dominated by the contribution from a heated outer accretion disk. This is similar to what has been found for the NIR flux from the brighter class of Z sources, but unlike the behavior of atolls fainter (L{sub X} ≈ 10{sup 36}-10{sup 37} erg s{sup –1}) than GX 3+1, where optically thin synchrotron emission from a jet probably dominates the NIR flux.

  20. Mental wellbeing amongst younger and older migrant workers in comparison to their urban counterparts in Guangzhou city, China: a cross-sectional study.

    Science.gov (United States)

    Li, Jie; Chang, Shu-Sen; Yip, Paul S F; Li, Juan; Jordan, Lucy P; Tang, Yunge; Hao, Yuantao; Huang, Xingmei; Yang, Ning; Chen, Chaoqi; Zeng, Qiaomei

    2014-12-16

    There has been a dramatic increase in internal migrant workers in China over recent decades, and there is a recent concern of poor mental health particularly amongst younger or "new generation" migrants who were born in 1980 or later. A cross-sectional study was conducted in Guangzhou city between May and July in 2012. Mental wellbeing was measured using the World Health Organization Five-item Well-Being Index Scale and the 36 Item Short Form Health Survey mental health scale. Linear and logistic regression models were used to investigate the differences between migrant workers and their urban counterparts and between younger and older migrants. Migrant workers (n = 914) showed a small but significant advantage in mental wellbeing compared to their urban counterparts (n = 814). There was some evidence for age modification effect (p for interaction = 0.055-0.095); better mental wellbeing in migrants than urbanites were mainly seen in the older compared to the younger group, and the difference attenuated somewhat after controlling for income satisfaction. Older migrants showed better mental health than younger migrants. Factors that were independently associated with poor mental health in migrants included being male, longer working hours, and income dissatisfaction, whilst older age, factory job, high income, and increased use of social support resources were associated with reduced risk. Efforts to promote mental health amongst migrant workers may be usefully targeted on younger migrants and include measures aimed to improve working conditions, strengthen the social support network, and address age-specific needs.

  1. Combined crossed molecular beam and ab initio investigation of the reaction of boron monoxide (BO; X(2)Σ(+)) with 1,3-butadiene (CH2CHCHCH2; X(1)Ag) and its deuterated counterparts.

    Science.gov (United States)

    Maity, Surajit; Dangi, Beni B; Parker, Dorian S N; Kaiser, Ralf I; Lin, Hong-Mao; E, Hai-Ping; Sun, Bing-Jian; Chang, A H H

    2015-02-19

    The reactions of the boron monoxide ((11)BO; X(2)Σ(+)) radical with 1,3-butadiene (CH2CHCHCH2; X(1)Ag) and its partially deuterated counterparts, 1,3-butadiene-d2 (CH2CDCDCH2; X(1)Ag) and 1,3-butadiene-d4 (CD2CHCHCD2; X(1)Ag), were investigated under single collision conditions exploiting a crossed molecular beams machine. The experimental data were combined with the state-of-the-art ab initio electronic structure calculations and statistical RRKM calculations to investigate the underlying chemical reaction dynamics and reaction mechanisms computationally. Our investigations revealed that the reaction followed indirect scattering dynamics through the formation of (11)BOC4H6 doublet radical intermediates via the barrierless addition of the (11)BO radical to the terminal carbon atom (C1/C4) and/or the central carbon atom (C2/C3) of 1,3-butadiene. The resulting long-lived (11)BOC4H6 intermediate(s) underwent isomerization and/or unimolecular decomposition involving eventually at least two distinct atomic hydrogen loss pathways to 1,3-butadienyl-1-oxoboranes (CH2CHCHCH(11)BO) and 1,3-butadienyl-2-oxoboranes (CH2C ((11)BO)CHCH2) in overall exoergic reactions via tight exit transition states. Utilizing partially deuterated 1,3-butadiene-d2 and -d4, we revealed that the hydrogen loss from the methylene moiety (CH2) dominated with 70 ± 10% compared to an atomic hydrogen loss from the methylidyne group (CH) of only 30 ± 10%; these data agree nicely with the theoretically predicted branching ratio of 80% versus 19%.

  2. Humidity Sensing Properties of Surface Modified Polyaniline Metal Oxide Composites

    Directory of Open Access Journals (Sweden)

    S. C. Nagaraju

    2014-01-01

    Full Text Available Polyaniline- (PANI praseodymium Oxide (Pr2O3 composites have been synthesized by in situ polymerization method with different weight percentages. The synthesized composites have been characterized by Fourier transform infrared spectroscopy, X-ray diffraction and scanning electron microscopy. The temperature dependent conductivity shows that the conductivity is due to the hopping of polarons and bipolarons. These composites show negative thermal coefficient (α behavior as a function of temperature, which is characteristic behavior of semiconducting materials. Sensor studies have been carried out by two-probe method and found that the sensitivity increases with increase in % RH. It is noticed that stability increase is due to the presence of Pr2O3 in polyaniline up to 30 wt%. A fast recovery and response time along with high sensitivity make these composites suitable for humidity sensors.

  3. Physico-chemical characterisation of surface modified particles for inhalation.

    Science.gov (United States)

    Stank, Katharina; Steckel, Hartwig

    2013-05-01

    Surface modification of drugs for inhalation is a possibility to influence interparticulate forces. This can be necessary to achieve a sufficient aerosolisation during powder inhalation as the cohesiveness of the micronised drug can be reduced. In addition, the interaction with propellants in pressurised metered dose inhaler can be changed. This can be used to improve the physical stability of the suspension based formulations. A dry particle coating process was used for the alteration of particle surfaces. The blending of micronised salbutamol sulphate (SBS) with different concentrations of magnesium stearate (Mgst) or glycerol monostearate (GMS) was followed by co-milling with an air jet mill. The powder properties were characterised by SEM, EDX, laser diffraction, BET and inverse gas chromatography. Physical mixtures generated by Turbula blending were compared to co-milled samples. A slight particle size reduction was determined. The Mgst deposition on SBS particles was detected by EDX measurements. The dispersive surface energy of SBS is lowered and the energy distribution is more homogenous for the co-milled samples. This study proves the application of co-milling for surface modification in the inhalation area. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Cellular interactions of surface modified nanoporous silicon particles.

    Science.gov (United States)

    Bimbo, Luis M; Sarparanta, Mirkka; Mäkilä, Ermei; Laaksonen, Timo; Laaksonen, Päivi; Salonen, Jarno; Linder, Markus B; Hirvonen, Jouni; Airaksinen, Anu J; Santos, Hélder A

    2012-05-21

    In this study, the self-assembly of hydrophobin class II (HFBII) on the surface of thermally hydrocarbonized porous silicon (THCPSi) nanoparticles was investigated. The HFBII-coating converted the hydrophobic particles into more hydrophilic ones, improved the particles' cell viability in both HT-29 and Caco-2 cell lines compared to uncoated particles, and enhanced the particles' cellular association. The amount of HFBII adsorbed onto the particles was also successfully quantified by both the BCA assay and a HPLC method. Importantly, the permeation of a poorly water-soluble drug, indomethacin, loaded into THCPSi particles across Caco-2 monolayers was not affected by the protein coating. In addition, (125)I-radiolabelled HFBII did not extensively permeate the Caco-2 monolayer and was found to be stably adsorbed onto the THCPSi nanoparticles incubated in pH 7.4, which renders the particles the possibility for further track-imaging applications. The results highlight the potential of HFBII coating for improving wettability, increasing biocompatibility and possible intestinal association of PSi nanoparticulates for drug delivery applications.

  5. Surface modified alginate microcapsules for 3D cell culture

    Science.gov (United States)

    Chen, Yi-Wen; Kuo, Chiung Wen; Chueh, Di-Yen; Chen, Peilin

    2016-06-01

    Culture as three dimensional cell aggregates or spheroids can offer an ideal platform for tissue engineering applications and for pharmaceutical screening. Such 3D culture models, however, may suffer from the problems such as immune response and ineffective and cumbersome culture. This paper describes a simple method for producing microcapsules with alginate cores and a thin shell of poly(L-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) to encapsulate mouse induced pluripotent stem (miPS) cells, generating a non-fouling surface as an effective immunoisolation barrier. We demonstrated the trapping of the alginate microcapsules in a microwell array for the continuous observation and culture of a large number of encapsulated miPS cells in parallel. miPS cells cultured in the microcapsules survived well and proliferated to form a single cell aggregate. Droplet formation of monodisperse microcapsules with controlled size combined with flow cytometry provided an efficient way to quantitatively analyze the growth of encapsulated cells in a high-throughput manner. The simple and cost-effective coating technique employed to produce the core-shell microcapsules could be used in the emerging field of cell therapy. The microwell array would provide a convenient, user friendly and high-throughput platform for long-term cell culture and monitoring.

  6. Efficiency of surface modified Ti coated with copper nanoparticles to ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 2. Efficiency of ... Titanium (Ti) used as condenser material in nuclear power plants encounter severe biofouling in marine environment which in turn affects the efficiency of the metal. ... Dates. Manuscript received: 17 July 2015; Accepted: 29 October 2015 ...

  7. Efficiency of surface modified Ti coated with copper nanoparticles to ...

    Indian Academy of Sciences (India)

    Abstract. Titanium (Ti) used as condenser material in nuclear power plants encounter severe biofouling in marine environment which in turn affects the efficiency of the metal. To reduce the biofouling by marine microorganisms, surface modification of the Ti was carried out by anodization process to obtain nanotubes ...

  8. The Ice Nucleation Activity of Surface Modified Soot

    Science.gov (United States)

    Häusler, Thomas; Witek, Lorenz; Felgitsch, Laura; Hitzenberger, Regina; Grothe, Hinrich

    2017-04-01

    The ice nucleation efficiency of many important atmospheric particles remains poorly understood. Since soot is ubiquitous in the Earth's troposphere, they might have the potential to significantly impact the Earth's climate (Finlayson-Pitts and Pitts, 2000; Seinfeld and Pandis, 1998). Here we present the ice nucleation activity (INA) in immersion freezing mode of different types of soot. Therefor a CAST (combustion aerosol standard) generator was used to produce different kinds of soot samples. The CAST generator combusts a propane-air-mixture and deposits thereby produced soot on a polyvinyl fluoride filter. By varying the propane to air ratio, the amount of organic portion of the soot can be varied from black carbon (BC) with no organic content to brown carbon (BrC) with high organic content. To investigate the impact of functional sites of ice nuclei (IN), the soot samples were exposed to NO2 gas for a certain amount of time (30 to 360 minutes) to chemically modify the surface. Immersion freezing experiments were carried out in a unique reaction gadget. In this device a water-in-oil suspension (with the soot suspended in the aqueous phase) was cooled till the freezing point and was observed through a microscope (Pummer et al., 2012; Zolles et al., 2015) It was found that neither modified nor unmodified BC shows INA. On the contrary, unmodified BrC shows an INA at -32˚ C, which can be increased up to -20˚ C. The INA of BrC depends on the duration of NO2- exposure. To clarify the characteristics of the surface modifications, surface sensitive analysis like infrared spectroscopy and X-ray photoelectron spectroscopy were carried out. Finlayson-Pitts, B. J. and Pitts, J. N. J.: Chemistry of the Upper and Lower Atmosphere, Elsevier, New York, 2000. Pummer, B. G., Bauer, H., Bernardi, J., Bleicher, S., and Grothe, H.: Suspendable macromolecules are responsible for ice nucleation activity of birch and conifer pollen, Atmos Chem Phys, 12, 2541-2550, 2012. Seinfeld, J. H. and Pandis, S. N.: Atmospheric Chemistry and Physics: From Air Pollution to Climate Change, Wiley-Interscience, N. J., 1998. Zolles, T., Burkart, J., Hausler, T., Pummer, B., Hitzenberger, R., and Grothe, H.: Identification of Ice Nucleation Active Sites on Feldspar Dust Particles, Journal of Physical Chemistry A, 119, 2692-2700, 2015.

  9. Glass carbon surface modified by the fluorine ion irradiation

    International Nuclear Information System (INIS)

    Teranishi, Yoshikazu; Ishizuka, Masanori; Kobayashi, Tomohiro; Nakamura, Isao; Uematu, Takahiko; Yasuda, Takeshi; Mitsuo, Atsushi; Morikawa, Kazuo

    2012-01-01

    Application of nano and micro fabrication techniques in industry requires solution to some crucial problems. One of the significant problems is the sticking interface between mold surface and imprinted polymer. In this study, we report a solution to the sticking interface problem by modification of nano imprinting mold using fluorine ion implantation. After the fluorine implantation, anti sticking layer appeared on the nano imprinting mold surface. After the implantation, a mold made from glass like carbon was patterned by focused ion beam lithography. The pattern was made up of word “TIRI”. The line width was varied with 300 nm, 500 nm, and 1 μm. The line depth was about 200 ∼ 300 nm. The average depth of implanted fluorine was approximately 90 nm. After imprinting, the resin was removed from the mold by mechanical lift-off process. Transferred pattern was observed and confirmed by a scanning electron microscope (SEM) and an atomic force microscope (AFM). The pattern transferred from mold to resin was found to be successful.

  10. Implication of surface modified NZVI particle retention in the porous ...

    Indian Academy of Sciences (India)

    Trishikhi Raychoudhury

    2017-06-15

    Jun 15, 2017 ... water velocity. In the third scenario, a constant head condition (Johnson et al. 2013) is assumed, and retention of CMC-NZVI particles and its impli- cations on porous media properties are assessed. In the third scenario, a change in porosity influences hydraulic conductivity and thus Darcy's flow rates. 2.

  11. The constitution and microstructure of laser surface-modified metals

    Science.gov (United States)

    Singh, Jogender

    1992-09-01

    The applications oflasers in the processing of metals, ceramics, and semiconductors range from surface glazing of thin films on semiconductors to thick surface cladding on metals. Lasers have the unique capability of rapid heating, melting, and quenching of the substrate, which results in the formation of new engineering materials with metastable microstructures. This article describes the microstructural evolution of laser-glazed and laser-clad alloys treated with a pulse or continuous-wave CO2 laser.

  12. Chemical switches and logic gates based on surface modified semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Konrad, Szacilowski; Wojciech, Macyk [Jagiellonian Univ., Dept. of Chemistry, Krakow (Poland)

    2006-02-15

    Photoelectrochemical properties of multicomponent photo-electrodes based on titanium dioxide and cadmium sulfide powders modified with hexacyanoferrate complexes have been examined. Photocurrent responses were recorded as functions of applied potential and photon energy. Surprisingly, the photocurrent can be switched between positive and negative values as a result of potential or photon energy changes. This new effect called Photo Electrochemical Photocurrent Switching (PEPS) opens a possibility of new chemical switches and logic gates construction. Boolean logic analysis and a tentative mechanism of the device are discussed. (authors)

  13. Surface modified carbon nanoparticle papers and applications on polymer composites

    Science.gov (United States)

    Ouyang, Xilian

    Free-standing paper like materials are usually employed as protective layers, chemical filters, components of electrical batteries or supercapacitors, adhesive layers, and electronic or optoelectric components. Free-standing papers made from carbon nanoparticles have drawn increased interest because they have a variety of superior chemical and physical characteristics, such as light weight, high intrinsic mechanical properties, and extraordinary high electrical conductivity. Nanopapers fabricated from 1- D shape carbon nanofibers (CNFs) and carbon nanotubes (CNTs) are promising reinforcing materials for polymer composites, because the highly porous CNF and CNT nanopapers (porosity ˜80% and ˜70% respectively) can be impregnated with matrix polymers. In the first part of this work, polyaniline (PANI) was used to functionalize the surface of CNFs, and the resultant carbon nanopapers presented impressive mechanical strength and electrical conductivity that it could be used in the in-mold coating (IMC)/ injection molding process to achieve high electromagnetic interference (EMI) shielding effectiveness. Aniline modified (AF) CNT nanopapers were used as a 3D network in gas separation membranes. The resultant composite membranes demonstrated better and stable CO2 permeance and CO 2/H2 selectivity in a high temperature (107°C) and high pressure (15-30 atm) gas separation process, not achievable by conventional polymer membranes. In the second part, we demonstrated that 2-D graphene (GP) or graphene oxide (GO) nanosheets could be tightly packed into a film which was impermeable to most gases and liquids. GP or GO nanopapers could be coated on polymer composites. In order to achieve well-dispersed single-layer graphene in aqueous medium, we developed a facile approach to synthesize functional GP bearing benzenesulfonic acid groups which allow the preparation of nanopapers by water based assembly. With the optimized processing conditions, our best GP nanopapers could reach a tensile strength of 360 MPa and an electrical conductivity of 4.45x104 S/m, much better than any similar materials reported in the literature. However, they didn't show good gas barrier properties. Since the GO paper presented zero gas permeability for both CO2 and H2, a hybrid paper fabrication approach was proposed to combine the advantages of individual GP and GO papers. This was done by filtering GP and GO layer by layer with GO sandwiched in between two layers of GP. The resulting hybrid papers showed high mechanical tensile strength and EMI shielding effectiveness that are close to GP nanopapers, and excellent gas barrier properties that comparable to GO nanopapers. The GP, GO and GP-Go-GP hybrid nanopapers have been successfully coated onto the thermoplastic surface by thermal lamination and injection molding. In the third part, the effect of PANI-CNF nanopapers and a chelating agent, 2, 4- Pentanedione (2, 4-P) on kinetics of an in-mold coating (IMC) resin was investigated. The results showed that the presence of amine functionalized carbon nanoparticles tended to retard the resin reaction, while 2, 4-P was capable of promoting the redox based free radical polymerization by forming a complex with the cobalt promoter in the initiation step. In order to understand the chemical and physical changes during the resin curing process, kinetics study on two major resin components, i.e. hexanediol diacrylate (HDDA) and styrene (St), were carried out using an integrated analysis design: differential scanning calorimetry (DSC) for overall reaction, Fourier transform infrared spectroscopy (FTIR) for individual component reactions, and rheometry for liquid-solid transition during the reaction. The gel point of this radical polymerization resin system was found to be <2% which implied that most curing was conducted in the solid phase. The results showed that the double bonds in acrylates and St followed an azeotropic polymerization pattern.

  14. Coupling of therapeutic molecules onto surface modified coralline hydroxyapatite.

    Science.gov (United States)

    Murugan, R; Ramakrishna, S

    2004-07-01

    Surface modification and coupling of therapeutic molecules, tetracycline, onto coralline hydroxyapatite (CHA) and their in vitro evaluations were described in this study. Initially, CHA was graft polymerized with glycidylmethacrylate (GMA) using redox initiators and subsequently coupled to tetracycline through epoxy groups. The CHA grafted with polyGMA (CHA-g-PGMA) was characterized by Fourier transform infrared spectroscopy and powder X-ray diffraction (XRD) for proof of grafting. The absorption peaks pertaining to epoxy and ester carbonyl groups were observed for the graft polymer due to PGMA grafting. The XRD results signified that there was no secondary phase in the apatite lattice and crystallinity was also not affected by grafting, which suggested that the PGMA chains were grafted only on the surface of CHA. Drug loading and releasing was evaluated and found that CHA-g-PGMA exhibited higher loading efficiency than CHA. The in vitro release of tetracycline was performed in phosphate buffered saline under physiological condition and the release profiles showed that the tetracycline-containing graft polymer releases the drug for prolonged period as compared to CHA. Based on the experimental results, CHA-g-PGMA appears to be a promising biomaterial for drug delivery.

  15. Implication of surface modified NZVI particle retention in the porous ...

    Indian Academy of Sciences (India)

    Trishikhi Raychoudhury

    2017-06-15

    Jun 15, 2017 ... cle retention resulted in an increase in pore water velocity (figure S2). This phenomenon is more prominent in finer sand columns and negligible in coarsest sand columns. In a constant flow sys- tem, Hosseini and Tosco (2013) have demonstrated that pore clogging results in increasing pressure.

  16. Eco-friendly aqueous core surface-modified nanocapsules.

    Science.gov (United States)

    Carbone, C; Musumeci, T; Lauro, M R; Puglisi, G

    2015-01-01

    In this work, positively charged nanocapsules have been developed for potential ocular delivery exploiting the deposition of PLA onto the droplet surface of a W/O nanoemulsion prepared by the reversed procedure of the PIT method. PLA in combination with different amounts of various oils and surfactants have been studied in order to select the best formulation for polymeric nanocapsule preparation. The traditional visual observation together with the Turbiscan(®) technology were exploited in order to identify the best combination of polymer/oil for nanocapsule preparation. Two different primary surfactants (Span(®) 60 and Span(®) 80) have been tested to select their influence on the field of existence of the nanoemulsion by the construction of the pseudoternary phase diagrams. Cationic hybrid NC have been prepared by the addition of a coating layer of DDAB. The physico-chemical and morphological properties of all the prepared nanocapsules have been evaluated and compared by PCS, DSC and AFM. Therefore, positively charged nanocapsules can be easily prepared by a simple eco-friendly technique that exploits biocompatible materials avoiding a large input of mechanical energy as a potential ocular delivery systems for hydrophilic compounds or gene materials. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Immunoadjuvant activity of the nanoparticles’ surface modified with mannan

    Science.gov (United States)

    Haddadi, Azita; Hamdy, Samar; Ghotbi, Zahra; Samuel, John; Lavasanifar, Afsaneh

    2014-09-01

    Mannan (MN) is the natural ligand for mannose receptors, which are widely expressed on dendritic cells (DCs). The purpose of this study was to assess the effect of formulation parameters on the immunogenicity of MN-decorated poly (D, L-lactide-co-glycolide) (PLGA) nanoparticles (NPs) in terms of their ability to stimulate DC phenotypic as well as functional maturation. For this purpose, NPs were formulated from either ester-terminated or COOH-terminated PLGA. Incorporation of MN in NPs was achieved through encapsulation, physical adsorption or chemical conjugation. Murine bone marrow derived DCs (BMDCs) were treated with various NP formulations and assessed for their ability to up-regulate DC cell surface markers, secrete immunostimulatory cytokines and to activate allogenic T cell responses. DCs treated with COOH-terminated PLGA-NPs containing chemically conjugated MN (MN-Cov-COOH) have shown superior performance in improving DC biological functions, compared to the rest of the formulations tested. This may be attributed to the higher level of MN incorporation in the former formulation. Incorporation of MN in PLGA NPs through chemical conjugation can lead to enhanced DC maturation and stimulatory function. This strategy may be used to develop more effective PLGA-based vaccine formulations.

  18. Enhancing osseointegration using surface-modified titanium implants

    Science.gov (United States)

    Yang, Y.; Oh, N.; Liu, Y.; Chen, W.; Oh, S.; Appleford, M.; Kim, S.; Kim, K.; Park, S.; Bumgardner, J.; Haggard, W.; Ong, J.

    2006-07-01

    Osseointegrated dental implants are used to replace missing teeth. The success of implants is due to osseointegration or the direct contact of the implant surface and bone without a fibrous connective tissue interface. This review discusses the enhancement of osseointegration by means of anodized microporous titanium surfaces, functionally macroporous graded titanium coatings, nanoscale titanium surfaces, and different bioactive factors.

  19. Surface-modified low-temperature solid oxide fuel cell

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Beom; Holme, Timothy P. [Department of Mechanical Engineering, Stanford University, Stanford, CA 94305 (United States); Guer, Turgut M. [Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305 (United States); Prinz, Fritz B. [Department of Mechanical Engineering, Stanford University, Stanford, CA 94305 (United States); Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305 (United States)

    2011-12-20

    This paper reports both experimental and theoretical results of the role of surface modification on the oxygen reduction reaction in low-temperature solid oxide fuel cells (LT-SOFC). Epitaxial ultrathin films of yttria-doped ceria (YDC) cathode interlayers (<10-130 nm) are grown by pulsed laser deposition (PLD) on single-crystalline YSZ(100). Fuel cell current-voltage measurements and electrochemical impedance spectroscopy are performed in the temperature range of 350 C {approx} 450 C. Quantum mechanical simulations of oxygen incorporation energetics support the experimental results and indicate a low activation energy of only 0.07 eV for YDC, while the incorporation reaction on YSZ is activated by a significantly higher energy barrier of 0.38 eV. Due to enhanced oxygen incorporation at the modified Pt/YDC interface, the cathodic interface resistance is reduced by two-fold, while fuel cell performance shows more than a two-fold enhancement with the addition of an ultrathin YDC interlayer at the cathode side of an SOFC element. The results of this study open up opportunities for improving cell performance, particularly of LT-SOFCs by adopting surface modification of YSZ surface with catalytically superior, ultrathin cathodic interlayers. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  20. STUDY OF SURFACE MODIFIED POLYMERS IN THE MODIFICATION OF NANOMATERIALS

    Directory of Open Access Journals (Sweden)

    G. V. Popov

    2014-01-01

    Full Text Available The comparative study of change of surface tension of solutions of some commercial rubbers before and after thermal ageing technique du-Nui, analyzed the features of change of surface tension of solutions of various rubbers in the presence of a mixture of fullerenes. Calculations of the Gibbs energy and the analysis of the obtained data to predict the behavior of polymer systems when changes are made to mix of fullerenes in a wide concentration range. When comparing the results of changes in Gibbs energy and the surface tension in fluids rubbers shown that mentioned above in solutions of elastomers aged, than the control. This fact confirms the initial chapeau of physic-chemical interactions of molecules fullerenes by segments of the Kuna and end groups of the polymer chains, as it is known that when thermal-oxidative degradation of rubbers, respectively the number of segments of the Kuna and branched loose ends of macromolecules that are free to react with fullerenes in solution, free from spatial constraints. A comparative analysis of the interaction of rubbers with different chemical composition with double branches has shown that it is easier to just react and has minimum energy polibutadien interaction that has to do with lack of branching and no radicals in its structure and in the backbone chain. The maximum energy of interaction with Fullerenes have SBS rubber because it has large styrene blocks in the main polymer chain that causes the spatial constraints to direct contact with fullerene molecules, you can assume that the interaction is only low-molecular fraction of Fullerenes mixture, possessing the necessary dimensions. As a result of the study shows that the application of the method of separation ring (Du-Nui allows you to predict the properties of rubber with modified nanomaterial’s with minimal labor costs.

  1. TypeScript revealed

    CERN Document Server

    Maharry, Dan

    2013-01-01

    TypeScript Revealed is a quick 100-page guide to Anders Hejlsberg's new take on JavaScript. With this brief, fast-paced introduction to TypeScript, .NET, Web and Windows 8 application developers who are already familiar with JavaScript will easily get up to speed with TypeScript and decide whether or not to start incorporating it into their own development. TypeScript is 'JavaScript for Application-scale development'; a superset of JavaScript that brings to it an additional object-oriented-like syntax familiar to .NET programmers that compiles down into simple, clean JavaScript that any browse

  2. Revealing the programming process

    DEFF Research Database (Denmark)

    Bennedsen, Jens; Caspersen, Michael Edelgaard

    2005-01-01

    One of the most important goals of an introductory programming course is that the students learn a systematic approach to the development of computer programs. Revealing the programming process is an important part of this; however, textbooks do not address the issue -- probably because...... the textbook medium is static and therefore ill-suited to expose the process of programming. We have found that process recordings in the form of captured narrated programming sessions are a simple, cheap, and efficient way of providing the revelation.We identify seven different elements of the programming...

  3. Recent Advances in Polymer Organic Light-Emitting Diodes (PLED) Using Non-conjugated Polymers as the Emitting Layer and Contrasting Them with Conjugated Counterparts

    Science.gov (United States)

    Wong, Michael Y.

    2017-11-01

    Polymer organic light-emitting diodes (PLED) are one of the most studied subjects in flexible electronics thanks to their economical wet fabrication procedure for enhanced price advantage of the product device. In order to optimize PLED efficiency, correlating the polymer structure with the device performance is essential. An important question for the researchers in this field is whether the polymer backbone is conjugated or not as it affects the device performance. In this review, recent advances in non-conjugated polymers employed as the emitting layer in PLED devices are first discussed, followed by their contrast with the conjugated counterparts in terms of polymer synthesis, sample quality, physical properties and device performances. Such comparison between conjugated and non-conjugated polymers for PLED applications is rarely attempted, and; hence, this review shall provide a useful insight of emitting polymers employed in PLEDs.

  4. Estimating detection rates for the LIGO-Virgo search for gravitational-wave burst counterparts to gamma-ray bursts using inferred local GRB rates

    International Nuclear Information System (INIS)

    Leonor, I; Frey, R; Sutton, P J; Jones, G; Marka, S; Marka, Z

    2009-01-01

    One of the ongoing searches performed using the LIGO-Virgo network of gravitational-wave interferometers is the search for gravitational-wave burst (GWB) counterparts to gamma-ray bursts (GRBs). This type of analysis makes use of GRB time and position information from gamma-ray satellite detectors to trigger the GWB search, and the GWB detection rates possible for such an analysis thus strongly depend on the GRB detection efficiencies of the satellite detectors. Using local GRB rate densities inferred from observations which are found in the science literature, we calculate estimates of the GWB detection rates for different configurations of the LIGO-Virgo network for this type of analysis.

  5. Life Disparity before, during and after Stagnation of Danish Female Life Expectancy. a Cause of Death Analysis and a Comparison with Their Scandinavian Counterparts

    DEFF Research Database (Denmark)

    Aburto, José Manuel; Wensink, Maarten Jan; Lindahl-Jacobsen, Rune

    Low lifespan tends to go with high lifespan inequality. We find that stagnation in lifespan of Danish women (roughly 1975-1995) was accompanied by a similar albeit shorter period of stagnation in lifespan inequality. Cause-specifically, we find that this stagnation results largely from death from...... cancers and non-infectious respiratory diseases, offsetting continuous improvement in cardiovascular mortality. Before and after stagnation, life expectancy increased as disparity decreased, as the cardiovascular revolution unfolded. Comparing Denmark and its Scandinavian counterparts, we find...... that as Norway increasingly came to resemble Sweden in terms of high life expectancy, it also came to resemble Sweden in terms of low lifespan inequality. Next, we aim to make similar decompositions for Sweden and Norway, and aim to disentangle cohort effects from the question: what can Denmark do now...

  6. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. VII. Properties of the Host Galaxy and Constraints on the Merger Timescale

    Energy Technology Data Exchange (ETDEWEB)

    Blanchard, P. K.; Berger, E.; Fong, W.; Nicholl, M.; Leja, J.; Conroy, C.; Alexander, K. D.; Margutti, R.; Williams, P. K. G.; Doctor, Z.; Chornock, R.; Villar, V. A.; Cowperthwaite, P. S.; Annis, J.; Brout, D.; Brown, D. A.; Chen, H. -Y.; Eftekhari, T.; Frieman, J. A.; Holz, D. E.; Metzger, B. D.; Rest, A.; Sako, M.; Soares-Santos, M.

    2017-10-16

    We present the properties of NGC 4993, the host galaxy of GW170817, the first gravitational wave (GW) event from the merger of a binary neutron star (BNS) system and the first with an electromagnetic (EM) counterpart. We use both archival photometry and new optical/near-IR imaging and spectroscopy, together with stellar population synthesis models to infer the global properties of the host galaxy. We infer a star formation history peaked at $\\gtrsim 10$ Gyr ago, with subsequent exponential decline leading to a low current star formation rate of 0.01 M$_{\\odot}$ yr$^{-1}$, which we convert into a binary merger timescale probability distribution. We find a median merger timescale of $11.2^{+0.7}_{-1.4}$ Gyr, with a 90% confidence range of $6.8-13.6$ Gyr. This in turn indicates an initial binary separation of $\\approx 4.5$ R$_{\\odot}$, comparable to the inferred values for Galactic BNS systems. We also use new and archival $Hubble$ $Space$ $Telescope$ images to measure a projected offset of the optical counterpart of $2.1$ kpc (0.64$r_{e}$) from the center of NGC 4993 and to place a limit of $M_{r} \\gtrsim -7.2$ mag on any pre-existing emission, which rules out the brighter half of the globular cluster luminosity function. Finally, the age and offset of the system indicates it experienced a modest natal kick with an upper limit of $\\sim 200$ km s$^{-1}$. Future GW$-$EM observations of BNS mergers will enable measurement of their population delay time distribution, which will directly inform their viability as the dominant source of $r$-process enrichment in the Universe.

  7. Android Emotions Revealed

    DEFF Research Database (Denmark)

    Vlachos, Evgenios; Schärfe, Henrik

    2012-01-01

    This work presents a method for designing facial interfaces for sociable android robots with respect to the fundamental rules of human affect expression. Extending the work of Paul Ekman towards a robotic direction, we follow the judgment-based approach for evaluating facial expressions to test...... in which case an android robot like the Geminoid|DK –a duplicate of an Original person- reveals emotions convincingly; when following an empirical perspective, or when following a theoretical one. The methodology includes the processes of acquiring the empirical data, and gathering feedback on them. Our...... findings are based on the results derived from a number of judgments, and suggest that before programming the facial expressions of a Geminoid, the Original should pass through the proposed procedure. According to our recommendations, the facial expressions of an android should be tested by judges, even...

  8. Chemistry of plutonium revealed

    International Nuclear Information System (INIS)

    Connick, R.E.

    1992-01-01

    In 1941 one goal of the Manhattan Project was to unravel the chemistry of the synthetic element plutonium as rapidly as possible. In this paper the work carried out at Berkeley from the spring of 1942 to the summer of 1945 is described briefly. The aqueous chemistry of plutonium is quite remarkable. Important insights were obtained from tracer experiments, but the full complexity was not revealed until macroscopic amounts (milligrams) became available. Because processes for separation from fission products were based on aqueous solutions, such solution chemistry was emphasized, particularly precipitation and oxidation-reduction behavior. The latter turned out to be unusually intricate when it was discovered that two more oxidation states existed in aqueous solution than had previously been suspected. Further, an equilibrium was rapidly established among the four aqueous oxidation states, while at the same time any three were not in equilibrium. These and other observations made while doing a crash study of a previously unknown element are reported

  9. Favorable Protonation of the (μ-edt)[Fe(2)(PMe(3))(4)(CO)(2)(H-terminal)](+) Hydrogenase Model Complex Over Its Bridging μ-H Counterpart: A Spectroscopic and DFT Study.

    Science.gov (United States)

    Galinato, Mary Grace I; Whaley, C Matthew; Roberts, Dean; Wang, Peng; Lehnert, Nicolai

    2011-03-01

    The mechanism of hydrogen production in [FeFe] hydrogenase remains elusive. However, a species featuring a terminal hydride bound to the distal Fe is thought to be the key intermediate leading to hydrogen production. In this study, density functional theory (DFT) calculations on the terminal (H-term) and bridging (μ-H) hydride isomers of (μ-edt)-[Fe(2)(PMe(3))(4)(CO)(2)H](+) are presented in order to understand the factors affecting their propensity for protonation. Relative to H-term, μ-H is 12.7 kcal/mol more stable, which contributes to its decreased reactivity towards an acid. Potential energy surface (PES) calculations for the reaction of the H-term isomer with 4-nitropyridinium, a proton source, further reveal a lower activation energy barrier (14.5 kcal/mol) for H-term than for μ-H (29 kcal/mol). Besides these energetic considerations, the H-term isomer displays a key molecular orbital (MO ) that has a relatively strong hydride (1s) contribution (23%), which is not present in the μ-H isomer. This indicates a potential orbital control of the reaction of the hydride complexes with acid. The lower activation energy barrier and this key MO together control the overall catalytic activity of (μ-edt)[Fe(2)(PMe(3))(4)(CO)(2)(H-term)](+). Lastly, Raman and IR spectroscopy were performed in order to probe the ν(Fe-H) stretching mode of the two isomers and their deuterated counterparts. A ν(Fe-H) stretching mode was observed for the μ-H complex at 1220 cm(-1). However, the corresponding mode is not observed for the less stable H-term isomer.

  10. Formation and infrared absorption of protonated naphthalenes (1-C10H9+ and 2-C10H9+) and their neutral counterparts in solid para-hydrogen.

    Science.gov (United States)

    Bahou, Mohammed; Wu, Yu-Jong; Lee, Yuan-Pern

    2013-02-14

    Protonated naphthalene (C(10)H(9)(+)) and its neutral counterparts (hydronaphthyl radicals, C(10)H(9)) are important intermediates in the reactions of aromatic compounds and in understanding the unidentified infrared (IR) emissions from interstellar media. We report the IR spectra of 1-C(10)H(9)(+), 2-C(10)H(9)(+), 1-C(10)H(9), and 2-C(10)H(9) trapped in solid para-hydrogen (p-H(2)); the latter three are new. These species were produced upon electron bombardment of a mixture of naphthalene (C(10)H(8)) and p-H(2) during matrix deposition. The intensities of IR features of 1-C(10)H(9)(+) decreased after the matrix was maintained in darkness for 19 h, whereas those of 1-C(10)H(9) and 2-C(10)H(9) increased. Irradiation of this matrix sample with light at 365 nm diminished lines of 1-C(10)H(9)(+) and 2-C(10)H(9) and enhanced lines of 1-C(10)H(9) and 2-C(10)H(9)(+); the latter species was unstable and converted to 1-C(10)H(9)(+) in less than 30 min and 2-C(10)H(9) was converted to 1-C(10)H(9) at 365 nm. Observed wavenumbers and relative intensities of these species agree satisfactorily with the anharmonic vibrational wavenumbers and IR intensities predicted with the B3PW91/6-311++G(2d,2p) method. Compared with spectra recorded previously with IR photodissociation of Ar-tagged C(10)H(9)(+) or IR multiphoton dissociation of C(10)H(9)(+), our method has the advantages of producing high-resolution IR spectra with a wide spectral coverage, true IR intensity and excellent ratio of signal to noise; both protonated species and their neutral counterparts are produced with little interference from other fragments. With these advantages, the IR spectra of 1-C(10)H(9)(+), 2-C(10)H(9)(+), 1-C(10)H(9), and 2-C(10)H(9) are here clearly characterized.

  11. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. II. UV, Optical, and Near-infrared Light Curves and Comparison to Kilonova Models

    Science.gov (United States)

    Cowperthwaite, P. S.; Berger, E.; Villar, V. A.; Metzger, B. D.; Nicholl, M.; Chornock, R.; Blanchard, P. K.; Fong, W.; Margutti, R.; Soares-Santos, M.; Alexander, K. D.; Allam, S.; Annis, J.; Brout, D.; Brown, D. A.; Butler, R. E.; Chen, H.-Y.; Diehl, H. T.; Doctor, Z.; Drout, M. R.; Eftekhari, T.; Farr, B.; Finley, D. A.; Foley, R. J.; Frieman, J. A.; Fryer, C. L.; García-Bellido, J.; Gill, M. S. S.; Guillochon, J.; Herner, K.; Holz, D. E.; Kasen, D.; Kessler, R.; Marriner, J.; Matheson, T.; Neilsen, E. H., Jr.; Quataert, E.; Palmese, A.; Rest, A.; Sako, M.; Scolnic, D. M.; Smith, N.; Tucker, D. L.; Williams, P. K. G.; Balbinot, E.; Carlin, J. L.; Cook, E. R.; Durret, F.; Li, T. S.; Lopes, P. A. A.; Lourenço, A. C. C.; Marshall, J. L.; Medina, G. E.; Muir, J.; Muñoz, R. R.; Sauseda, M.; Schlegel, D. J.; Secco, L. F.; Vivas, A. K.; Wester, W.; Zenteno, A.; Zhang, Y.; Abbott, T. M. C.; Banerji, M.; Bechtol, K.; Benoit-Lévy, A.; Bertin, E.; Buckley-Geer, E.; Burke, D. L.; Capozzi, D.; Carnero Rosell, A.; Carrasco Kind, M.; Castander, F. J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; Davis, C.; DePoy, D. L.; Desai, S.; Dietrich, J. P.; Drlica-Wagner, A.; Eifler, T. F.; Evrard, A. E.; Fernandez, E.; Flaugher, B.; Fosalba, P.; Gaztanaga, E.; Gerdes, D. W.; Giannantonio, T.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; Honscheid, K.; Jain, B.; James, D. J.; Jeltema, T.; Johnson, M. W. G.; Johnson, M. D.; Kent, S.; Krause, E.; Kron, R.; Kuehn, K.; Nuropatkin, N.; Lahav, O.; Lima, M.; Lin, H.; Maia, M. A. G.; March, M.; Martini, P.; McMahon, R. G.; Menanteau, F.; Miller, C. J.; Miquel, R.; Mohr, J. J.; Neilsen, E.; Nichol, R. C.; Ogando, R. L. C.; Plazas, A. A.; Roe, N.; Romer, A. K.; Roodman, A.; Rykoff, E. S.; Sanchez, E.; Scarpine, V.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, M.; Smith, R. C.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Thomas, R. C.; Troxel, M. A.; Vikram, V.; Walker, A. R.; Wechsler, R. H.; Weller, J.; Yanny, B.; Zuntz, J.

    2017-10-01

    We present UV, optical, and near-infrared (NIR) photometry of the first electromagnetic counterpart to a gravitational wave source from Advanced Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo, the binary neutron star merger GW170817. Our data set extends from the discovery of the optical counterpart at 0.47-18.5 days post-merger, and includes observations with the Dark Energy Camera (DECam), Gemini-South/FLAMINGOS-2 (GS/F2), and the Hubble Space Telescope (HST). The spectral energy distribution (SED) inferred from this photometry at 0.6 days is well described by a blackbody model with T≈ 8300 K, a radius of R≈ 4.5× {10}14 cm (corresponding to an expansion velocity of v≈ 0.3c), and a bolometric luminosity of {L}{bol}≈ 5× {10}41 erg s-1. At 1.5 days we find a multi-component SED across the optical and NIR, and subsequently we observe rapid fading in the UV and blue optical bands and significant reddening of the optical/NIR colors. Modeling the entire data set, we find that models with heating from radioactive decay of 56Ni, or those with only a single component of opacity from r-process elements, fail to capture the rapid optical decline and red optical/NIR colors. Instead, models with two components consistent with lanthanide-poor and lanthanide-rich ejecta provide a good fit to the data; the resulting “blue” component has {M}{ej}{blue}≈ 0.01 {M}⊙ and {v}{ej}{blue}≈ 0.3 {{c}}, and the “red” component has {M}{ej}{red}≈ 0.04 {M}⊙ and {v}{ej}{red}≈ 0.1 {{c}}. These ejecta masses are broadly consistent with the estimated r-process production rate required to explain the Milky Way r-process abundances, providing the first evidence that binary neutron star (BNS) mergers can be a dominant site of r-process enrichment.

  12. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. II. UV, Optical, and Near-infrared Light Curves and Comparison to Kilonova Models

    Energy Technology Data Exchange (ETDEWEB)

    Cowperthwaite, P. S.; Berger, E.; Villar, V. A.; Metzger, B. D.; Nicholl, M.; Chornock, R.; Blanchard, P. K.; Fong, W.; Margutti, R.; Soares-Santos, M.; Alexander, K. D.; Allam, S.; Annis, J.; Brout, D.; Brown, D. A.; Butler, R. E.; Chen, H. -Y.; Diehl, H. T.; Doctor, Z.; Drout, M. R.; Eftekhari, T.; Farr, B.; Finley, D. A.; Foley, R. J.; Frieman, J. A.; Fryer, C. L.; García-Bellido, J.; Gill, M. S. S.; Guillochon, J.; Herner, K.; Holz, D. E.; Kasen, D.; Kessler, R.; Marriner, J.; Matheson, T.; Neilsen, E. H.; Quataert, E.; Palmese, A.; Rest, A.; Sako, M.; Scolnic, D. M.; Smith, N.; Tucker, D. L.; Williams, P. K. G.; Balbinot, E.; Carlin, J. L.; Cook, E. R.; Durret, F.; Li, T. S.; Lopes, P. A. A.; Lourenço, A. C. C.; Marshall, J. L.; Medina, G. E.; Muir, J.; Muñoz, R. R.; Sauseda, M.; Schlegel, D. J.; Secco, L. F.; Vivas, A. K.; Wester, W.; Zenteno, A.; Zhang, Y.; Abbott, T. M. C.; Banerji, M.; Bechtol, K.; Benoit-Lévy, A.; Bertin, E.; Buckley-Geer, E.; Burke, D. L.; Capozzi, D.; Carnero Rosell, A.; Carrasco Kind, M.; Castander, F. J.; Crocce, M.; Cunha, C. E.; D’Andrea, C. B.; Costa, L. N. da; Davis, C.; DePoy, D. L.; Desai, S.; Dietrich, J. P.; Drlica-Wagner, A.; Eifler, T. F.; Evrard, A. E.; Fernandez, E.; Flaugher, B.; Fosalba, P.; Gaztanaga, E.; Gerdes, D. W.; Giannantonio, T.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; Honscheid, K.; Jain, B.; James, D. J.; Jeltema, T.; Johnson, M. W. G.; Johnson, M. D.; Kent, S.; Krause, E.; Kron, R.; Kuehn, K.; Nuropatkin, N.; Lahav, O.; Lima, M.; Lin, H.; Maia, M. A. G.; March, M.; Martini, P.; McMahon, R. G.; Menanteau, F.; Miller, C. J.; Miquel, R.; Mohr, J. J.; Neilsen, E.; Nichol, R. C.; Ogando, R. L. C.; Plazas, A. A.; Roe, N.; Romer, A. K.; Roodman, A.; Rykoff, E. S.; Sanchez, E.; Scarpine, V.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, M.; Smith, R. C.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Thomas, R. C.; Troxel, M. A.; Vikram, V.; Walker, A. R.; Wechsler, R. H.; Weller, J.; Yanny, B.; Zuntz, J.

    2017-10-16

    We present UV, optical, and NIR photometry of the first electromagnetic counterpart to a gravitational wave source from Advanced LIGO/Virgo, the binary neutron star merger GW170817. Our data set extends from the discovery of the optical counterpart at $0.47$ days to $18.5$ days post-merger, and includes observations with the Dark Energy Camera (DECam), Gemini-South/FLAMINGOS-2 (GS/F2), and the {\\it Hubble Space Telescope} ({\\it HST}). The spectral energy distribution (SED) inferred from this photometry at $0.6$ days is well described by a blackbody model with $T\\approx 8300$ K, a radius of $R\\approx 4.5\\times 10^{14}$ cm (corresponding to an expansion velocity of $v\\approx 0.3c$), and a bolometric luminosity of $L_{\\rm bol}\\approx 5\\times10^{41}$ erg s$^{-1}$. At $1.5$ days we find a multi-component SED across the optical and NIR, and subsequently we observe rapid fading in the UV and blue optical bands and significant reddening of the optical/NIR colors. Modeling the entire data set we find that models with heating from radioactive decay of $^{56}$Ni, or those with only a single component of opacity from $r$-process elements, fail to capture the rapid optical decline and red optical/NIR colors. Instead, models with two components consistent with lanthanide-poor and lanthanide-rich ejecta provide a good fit to the data, the resulting "blue" component has $M_\\mathrm{ej}^\\mathrm{blue}\\approx 0.01$ M$_\\odot$ and $v_\\mathrm{ej}^\\mathrm{blue}\\approx 0.3$c, and the "red" component has $M_\\mathrm{ej}^\\mathrm{red}\\approx 0.04$ M$_\\odot$ and $v_\\mathrm{ej}^\\mathrm{red}\\approx 0.1$c. These ejecta masses are broadly consistent with the estimated $r$-process production rate required to explain the Milky Way $r$-process abundances, providing the first evidence that BNS mergers can be a dominant site of $r$-process enrichment.

  13. Acute glycemic and blood lipid response to the ingestion of a candy bar-like protein supplement compared with its candy bar counterpart.

    Science.gov (United States)

    Dugan, Kristin; Campbell, Bill; Dufour, Fanny; Roman, Sara; Woodall, Caleb; McAdams, Mallory; White, Andrew; Taylor, Lem W; Wilborn, Colin D

    2013-05-01

    Candy bar-like protein supplements are sometimes consumed for their sugar alcohol content, which lowers the glycemic response. The purpose of this study was to determine the acute glycemic and blood lipid response to the ingestion of a candy bar-like protein supplement compared with its candy bar counterpart. In a crossover design, 5 males and 5 females (N = 10; age, 24 ± 5.5 years; height, 174 ± 8.3 cm; weight, 80 ± 21.9 kg) consumed a candy bar (CBR) or a similar protein bar (PBR) after a 10-h fast. Blood draws occurred at baseline and at 15, 30, 45, and 60 min after consumption and were analyzed for blood glucose, insulin, and lipid profiles. A 2×5 ANOVA was used, with Student's t tests for significant interactions. A significant (p 0.05) was observed in total cholesterol. Blood glucose, triglycerides, and insulin all increased significantly in response to both CBR and PBR consumption. The CBR elicited a greater effect on blood glucose; however, the PBR had a strong impact on serum triglycerides and insulin.

  14. A comparison between SALT/SAAO observations and kilonova models for AT 2017gfo: the first electromagnetic counterpart of a gravitational wave transient - GW170817

    Science.gov (United States)

    Buckley, David A. H.; Andreoni, Igor; Barway, Sudhanshu; Cooke, Jeff; Crawford, Steven M.; Gorbovskoy, Evgeny; Gromadzki, Mariusz; Lipunov, Vladimir; Mao, Jirong; Potter, Stephen B.; Pretorius, Magaretha L.; Pritchard, Tyler A.; Romero-Colmenero, Encarni; Shara, Michael M.; Väisänen, Petri; Williams, Ted B.

    2018-02-01

    We report on SALT low-resolution optical spectroscopy and optical/IR photometry undertaken with other SAAO telescopes (MASTER-SAAO and IRSF) of the kilonova AT 2017gfo (a.k.a. SSS17a) in the galaxy NGC4993 during the first 10 d of discovery. This event has been identified as the first ever electromagnetic counterpart of a gravitational wave event, namely GW170817, which was detected by the LIGO and Virgo gravitational wave observatories. The event is likely due to a merger of two neutron stars, resulting in a kilonova explosion. SALT was the third observatory to obtain spectroscopy of AT 2017gfo and the first spectrum, 1.2 d after the merger, is quite blue and shows some broad features, but no identifiable spectral lines and becomes redder by the second night. We compare the spectral and photometric evolution with recent kilonova simulations and conclude that they are in qualitative agreement for post-merger wind models with proton:nucleon ratios of Ye = 0.25-0.30. The blue colour of the first spectrum is consistent with the lower opacity of the lanthanide-free r-process elements in the ejecta. Differences between the models and observations are likely due to the choice of system parameters combined with the absence of atomic data for more elements in the ejecta models.

  15. ROSA/LSTF Test and RELAP5 Analyses on PWR Cold Leg Small-Break LOCA with Accident Management Measure and PKL Counterpart Test

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Takeshi; Ohtsu, Iwao [Nuclear Safety Research Center, Japan Atomic Energy Agency, Tokaimura (Japan)

    2017-08-15

    An experiment using the Primaerkreislaeufe Versuchsanlage (PKL) was performed for the OECD/NEA PKL-3 Project as a counterpart to a previous test with the large-scale test facility (LSTF) on a cold leg small-break loss-of-coolant accident with an accident management (AM) measure in a pressurized water reactor. Concerning the AM measure, the rate of steam generator (SG) secondary-side depressurization was controlled to achieve a primary depressurization rate of 200 K/h as a common test condition; however, the onset timings of the SG depressurization were different from each other. In both tests, rapid recovery started in the core collapsed liquid level after loop seal clearing, which caused whole core quench. Some discrepancies appeared between the LSTF and PKL test results for the core collapsed liquid level, the cladding surface temperature, and the primary pressure. The RELAP5/MOD3.3 code predicted the overall trends of the major thermal-hydraulic responses observed in the LSTF test well, and indicated a remaining problem in the prediction of primary coolant distribution. Results of uncertainty analysis for the LSTF test clarified the influences of the combination of multiple uncertain parameters on peak cladding temperature within the defined uncertain ranges.

  16. Cost of Mating and Insemination Capacity of a Genetically Modified Mosquito Aedes aegypti OX513A Compared to Its Wild Type Counterpart

    Science.gov (United States)

    Bargielowski, Irka; Alphey, Luke; Koella, Jacob C.

    2011-01-01

    The idea of implementing genetics-based insect control strategies modelled on the traditional SIT is becoming increasingly popular. In this paper we compare a genetically modified line of Aedes aegypti carrying a tetracycline repressible, lethal positive feedback system (OX513A) with its wild type counterpart with respect to their insemination capacities and the cost of courtship and mating. Genetically modified males inseminated just over half as many females as the wild type males during their lifetime. Providing days of rest from mating had no significant effect on the total number of females inseminated by males of either line, but it did increase their longevity. Producing sperm had a low cost in terms of energy investment; the cost of transferring this sperm to a receptive female was much higher. Continued mating attempts with refractory females suggest that males could not identify refractory females before investing substantial energy in courtship. Although over a lifetime OX513A males inseminated fewer females, the number of females inseminated over the first three days, was similar between males of the two lines, suggesting that the identified cost of RIDL may have little impact on the outcome of SIT-based control programmes with frequent releases of the genetically modified males. PMID:22022518

  17. ROSA/LSTF Test and RELAP5 Analyses on PWR Cold Leg Small-Break LOCA with Accident Management Measure and PKL Counterpart Test

    Directory of Open Access Journals (Sweden)

    Takeshi Takeda

    2017-08-01

    Full Text Available An experiment using the Primӓrkreislӓufe Versuchsanlage (PKL was performed for the OECD/NEA PKL-3 Project as a counterpart to a previous test with the large-scale test facility (LSTF on a cold leg small-break loss-of-coolant accident with an accident management (AM measure in a pressurized water reactor. Concerning the AM measure, the rate of steam generator (SG secondary-side depressurization was controlled to achieve a primary depressurization rate of 200 K/h as a common test condition; however, the onset timings of the SG depressurization were different from each other. In both tests, rapid recovery started in the core collapsed liquid level after loop seal clearing, which caused whole core quench. Some discrepancies appeared between the LSTF and PKL test results for the core collapsed liquid level, the cladding surface temperature, and the primary pressure. The RELAP5/MOD3.3 code predicted the overall trends of the major thermal-hydraulic responses observed in the LSTF test well, and indicated a remaining problem in the prediction of primary coolant distribution. Results of uncertainty analysis for the LSTF test clarified the influences of the combination of multiple uncertain parameters on peak cladding temperature within the defined uncertain ranges.

  18. Comparative Proteomic Analysis of Two Varieties of Genetically Modified (GM) Embrapa 5.1 Common Bean (Phaseolus vulgaris L.) and Their Non-GM Counterparts.

    Science.gov (United States)

    Balsamo, Geisi M; Valentim-Neto, Pedro A; Mello, Carla S; Arisi, Ana C M

    2015-12-09

    The genetically modified (GM) common bean event Embrapa 5.1 was commercially approved in Brazil in 2011; it is resistant to golden mosaic virus infection. In the present work grain proteome profiles of two Embrapa 5.1 common bean varieties, Pérola and Pontal, and their non-GM counterparts were compared by two-dimensional gel electrophoresis (2-DE) followed by mass spectrometry (MS). Analyses detected 23 spots differentially accumulated between GM Pérola and non-GM Pérola and 21 spots between GM Pontal and non-GM Pontal, although they were not the same proteins in Pérola and Pontal varieties, indicating that the variability observed may not be due to the genetic transformation. Among them, eight proteins were identified in Pérola varieties, and four proteins were identified in Pontal. Moreover, we applied principal component analysis (PCA) on 2-DE data, and variation between varieties was explained in the first two principal components. This work provides a first 2-DE-MS/MS-based analysis of Embrapa 5.1 common bean grains.

  19. Design of a high performance thin all-solid-state supercapacitor mimicking the active interface of its liquid-state counterpart.

    Science.gov (United States)

    Anothumakkool, Bihag; Torris A T, Arun; Bhange, Siddheshwar N; Unni, Sreekuttan M; Badiger, Manohar V; Kurungot, Sreekumar

    2013-12-26

    Here we report an all-solid-state supercapacitor (ASSP) which closely mimics the electrode-electrolyte interface of its liquid-state counterpart by impregnating polyaniline (PANI)-coated carbon paper with polyvinyl alcohol-H2SO4 (PVA-H2SO4) gel/plasticized polymer electrolyte. The well penetrated PVA-H2SO4 network along the porous carbon matrix essentially enhanced the electrode-electrolyte interface of the resulting device with a very low equivalent series resistance (ESR) of 1 Ω/cm(2) and established an interfacial structure very similar to a liquid electrolyte. The designed interface of the device was confirmed by cross-sectional elemental mapping and scanning electron microscopy (SEM) images. The PANI in the device displayed a specific capacitance of 647 F/g with an areal capacitance of 1 F/cm(2) at 0.5 A/g and a capacitance retention of 62% at 20 A/g. The above values are the highest among those reported for any solid-state-supercapacitor. The whole device, including the electrolyte, shows a capacitance of 12 F/g with a significantly low leakage current of 16 μA(2). Apart from this, the device showed excellent stability for 10000 cycles with a coulombic efficiency of 100%. Energy density of the PANI in the device is 14.3 Wh/kg.

  20. Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow–derived counterparts

    Directory of Open Access Journals (Sweden)

    Daniel Blashki

    2016-08-01

    Full Text Available In this study, we show that matrix dense cortical bone is the more potent compartment of bone than bone marrow as a stromal source for mesenchymal stem cells as isolated from adult rats. Lineage-depleted cortical bone-mesenchymal stem cells demonstrated >150-fold enrichment of colony forming unit–fibroblasts per cell incidence. compared to lineage-depleted bone marrow-mesenchymal stem cells, corresponding to a 70-fold increase in absolute recovered colony forming unit–fibroblasts. The composite phenotype Lin−/CD45−/CD31−/VLA-1+/Thy-1+ enriched for clonogenic mesenchymal stem cells solely from cortical bone–derived cells from which 70% of clones spontaneously differentiated into all lineages of bone, cartilage, and adipose. Both populations generated vascularized bone tissue within subcutaneous implanted collagen scaffolds; however, cortical bone–derived cells formed significantly more osteoid than bone marrow counterparts, quantified by histology. The data demonstrate that our isolation protocol identifies and validates mesenchymal stem cells with superior clonal, proliferative, and developmental potential from cortical bone compared to the bone marrow niche although marrow persists as the typical source for mesenchymal stem cells both in the literature and current pre-clinical therapies.

  1. Identification, molecular and functional characterization of calmodulin gene of Phytomonas serpens 15T that shares high similarity with its pathogenic counterparts Trypanosoma cruzi.

    Science.gov (United States)

    de Souza, Tatiana de Arruda Campos Brasil; Graça-de Souza, Viviane Krominski; Lancheros, César Armando Contreras; Monteiro-Góes, Viviane; Krieger, Marco Aurélio; Goldenberg, Samuel; Yamauchi, Lucy Megumi; Yamada-Ogatta, Sueli Fumie

    2011-03-01

    In trypanosomatids, Ca²+-binding proteins can affect parasite growth, differentiation and invasion. Due to their importance for parasite maintenance, they become an attractive target for drug discovery and design. Phytomonas serpens 15T is a non-human pathogenic trypanosomatid that expresses important protein homologs of human pathogenic trypanosomatids. In this study, the coding sequence of calmodulin, a Ca²+-binding protein, of P. serpens 15T was cloned and characterized. The encoded polypeptide (CaMP) displayed high amino acid identity to homolog protein of Trypanosoma cruzi and four helix-loop-helix motifs were found. CaMP sequence analysis showed 20 amino acid substitutions compared to its mammalian counterparts. This gene is located on a chromosomal band with estimated size of 1,300 kb and two transcripts were detected by Northern blot analysis. A polyclonal antiserum raised against the recombinant protein recognized a polypeptide with an estimated size of 17 kDa in log-phase promastigote extracts. The recombinant CaMP retains its Ca²+-binding capacity.

  2. Analysis of SBLOCA-counterpart test-in PSB-VVER facility by Cathare2: quantitative/qualitative accuracy evaluation and comparison with RELAP5 code

    International Nuclear Information System (INIS)

    Nevo, A.D.; Araneo, D.; Cherubini, M.; D'Auria, F.; Galassi, G.M.; Petruzzi, A.

    2005-01-01

    This paper deals with the Cathare2 analysis of SBLOCA transient, counterpart of the LOBI facility experiment, that has been performed in the Integral Test Facility (ITF) PSB-VVER, installed at EREC (Electrogorsk, Russia), in the framework of the OECD PSB-VVER Project. This effort has been performed in the framework of a larger objective: the creation of the database of error specific for the Cathare2 code, suitable for application to DBA and BDBA conditions (including AM scenarios) as needed for the licensing process. The calculation has been performed using Cathare2V1.5B computer code and its accuracy has been demonstrated by qualitative and quantitative evaluation reported in the present document. The quantitative analysis has been performed adopting a method developed at DIMNP, which has capabilities in quantifying the errors in code predictions related to the measured experimental signal; the Fast Fourier Transform (FFT) is used aiming to have an integral representation of the code calculation discrepancies (i.e. error between measured and calculated time trends) in the frequency domain. Sensitivity analyses have been addressed to evaluate the influence of the heat losses upon the predicted transient evolution. Finally a comparison with previous Relap5/Mod3.3 code application to the same test are also included. (authors)

  3. Electrodeposited polyethylenedioxythiophene with infiltrated gel electrolyte interface: a close contest of an all-solid-state supercapacitor with its liquid-state counterpart

    Science.gov (United States)

    Anothumakkool, Bihag; Torris A. T, Arun; Bhange, Siddheshwar N.; Badiger, Manohar V.; Kurungot, Sreekumar

    2014-05-01

    We report the design of an all-solid-state supercapacitor, which has charge storage characteristics closely matching that of its liquid-state counterpart even under extreme temperature and humidity conditions. The prototype is made by electro-depositing polyethylenedioxythiophene (PEDOT) onto the individual carbon fibers of a porous carbon substrate followed by intercalating the matrix with polyvinyl alcohol-sulphuric acid (PVA-H2SO4) gel electrolyte. The electrodeposited layer of PEDOT maintained a flower-like growth pattern along the threads of each carbon fiber. This morphology and the alignment of PEDOT led to an enhanced surface area and electrical conductivity, and the pores in the system enabled effective intercalation of the polymer-gel electrolyte. Thus, the established electrode-electrolyte interface nearly mimics that of its counterpart based on the liquid electrolyte. Consequently, the solid device attained very low internal resistance (1.1 Ω cm-2) and a high specific capacitance (181 F g-1) for PEDOT at a discharge current density of 0.5 A g-1. Even with a high areal capacitance of 836 mF cm-2 and volumetric capacitance of 28 F cm-3, the solid device retained a mass-specific capacitance of 111 F g-1 for PEDOT. This is in close agreement with the value displayed by the corresponding liquid-state system (112 F g-1), which was fabricated by replacing the gel electrolyte with 0.5 M H2SO4. The device also showed excellent charge-discharge stability for 12 000 cycles at 5 A g-1. The performance of the device was consistent even under wide-ranging humidity (30-80%) and temperature (-10 to 80 °C) conditions. Finally, a device fabricated by increasing the electrode area four times was used to light an LED, which validated the scalability of the process.We report the design of an all-solid-state supercapacitor, which has charge storage characteristics closely matching that of its liquid-state counterpart even under extreme temperature and humidity conditions

  4. The Relationship between the Movements of Capital Markets in Developed Economies and Their Emerging Market Counterparts in The Asian Paciic Region

    Directory of Open Access Journals (Sweden)

    Noor Azlinna Azizan

    2014-08-01

    Full Text Available This research revisits at the relationship between the movements of capital markets in developed  economies  and  their  emerging  market  counterparts  in  the  Asian  Paciic  region using market indices of the American, British, Malaysian, Singaporean, Mainland Chinese, Hong Kong Special Administrative Region (SAR, Indian, Japanese and Australian markets for  the  periods  1997  to  2007.  The  Johansen's  Cointegration  Test,  and  Vector  Correction Model  Test  were  used  to  determine  the  long  term  relationship  between  the  markets.  This study inds that the Asian markets are very much inluenced by the events in the United States rather  than  other  developed  markets.  Of  all  the  markets  being  surveyed,  The  South  East Asian markets are the most sensitive towards events in their own region and regions outside themselves. Mainland China in the long run is not affected by events outside themselves.  ";} // -->activate javascript

  5. Comparative transcriptome profiling of an SV40-transformed human fibroblast (MRC5CVI) and its untransformed counterpart (MRC-5) in response to UVB irradiation.

    Science.gov (United States)

    Chang, Cheng-Wei; Chen, Chaang-Ray; Huang, Chao-Ying; Shu, Wun-Yi; Chiang, Chi-Shiun; Hong, Ji-Hong; Hsu, Ian C

    2013-01-01

    Simian virus 40 (SV40) transforms cells through the suppression of tumor-suppressive responses by large T and small t antigens; studies on the effects of these two oncoproteins have greatly improved our knowledge of tumorigenesis. Large T antigen promotes cellular transformation by binding and inactivating p53 and pRb tumor suppressor proteins. Previous studies have shown that not all of the tumor-suppressive responses were inactivated in SV40-transformed cells; however, the underlying cause is not fully studied. In this study, we investigated the UVB-responsive transcriptome of an SV40-transformed fibroblast (MRC5CVI) and that of its untransformed counterpart (MRC-5). We found that, in response to UVB irradiation, MRC-5 and MRC5CVI commonly up-regulated the expression of oxidative phosphorylation genes. MRC-5 up-regulated the expressions of chromosome condensation, DNA repair, cell cycle arrest, and apoptotic genes, but MRC5CVI did not. Further cell death assays indicated that MRC5CVI was more sensitive than MRC-5 to UVB-induced cell death with increased caspase-3 activation; combining with the transcriptomic results suggested that MRC5CVI may undergo UVB-induced cell death through mechanisms other than transcriptional regulation. Our study provides a further understanding of the effects of SV40 transformation on cellular stress responses, and emphasizes the value of SV40-transformed cells in the researches of sensitizing neoplastic cells to radiations.

  6. Do direito incondicional à condicionalidade do direito: as contrapartidas do Programa Bolsa Família Unconditional to conditional rights: counterparts in Brazil's Family Allowance Program

    Directory of Open Access Journals (Sweden)

    Giselle Lavinas Monnerat

    2007-12-01

    Full Text Available Este artigo analisa a concepção e desafios em torno da exigência de contrapartidas do Programa Bolsa Família (PBF. A obrigatoriedade de inserção de crianças e adolescentes na escola e de crianças, gestantes e nutrizes nos serviços de saúde é central no desenho do PBF e, à semelhança do que ocorre em outros países, tem sido alvo de intensa polêmica. Busca-se, assim, mapear a discussão teórica que embasa os argumentos favoráveis e contrários aos programas de transferência monetária condicionada, utilizando como estratégia metodológica a sistematização bibliográfica e estudo da legislação do PBF. A análise demonstra que, se de um lado, estão aqueles que rejeitam as contrapartidas sob alegação de que estas feririam o direito incondicional de cidadania, de outro, situam-se os que defendem as condicionalidades sob argumentos distintos. Aqui estão tanto concepções que entendem que é preciso dar algo em troca do recebimento do benefício quanto aquelas que vêem tais exigências como estratégia para favorecer o acesso aos serviços sociais e romper o ciclo da pobreza. Esta última visão está presente nos documentos oficiais do programa. Porém, na legislação complementar, a operacionalização das condicionalidades é definida de forma coercitiva, distanciando-se da concepção de inserção social.This paper analyzes the concepts and challenges of the counterpart contributions demanded by Brazil's Family Allowance Program, which requires mandatory school attendance for children and adolescents, and healthcare for children, pregnant women and breast-feeding mothers. These issues are prompting much discussion in Brazil and elsewhere in the world. This study charts theoretical aspects that underpin arguments for and against conditional cash transfer programs, through a review and systematization of the literature and a study of the related legislation. This analysis demonstrates that the opponents of counterpart

  7. Farnesol-like endogenous sesquiterpenoids in vertebrates: the probable but overlooked functional "inbrome" anti-aging counterpart of juvenile hormone of insects?

    Directory of Open Access Journals (Sweden)

    Arnold eDe Loof

    2015-01-01

    Full Text Available Literature on the question whether the juvenile stage of vertebrates is hormonally regulated is scarce. It seems to be intuitively assumed that this stage of development is automated, and does not require any specific hormone(s. Such reasoning mimics the state of affairs in insects until it was shown that surgical removal of a tiny pair of glands in the head, the corpora allata, ended larval life and initiated metamorphosis. Decades later, the responsible hormone was found and named juvenile hormone (JH because when present, it makes a larva molt into another larval stage. JH is a simple ester of farnesol, a sesquiterpenoid present in all eukaryotes. Whereas vertebrates do not have an anatomical counterpart of the corpora allata, their tissues do contain farnesol-like sesquiterpenoids (FLS. Some display typical JH activity when tested in appropriate insect bioassays. Some FLS are intermediates in the biosynthetic pathway of cholesterol, a compound that insects and nematodes (= Ecdysozoa cannot synthesize by themselves. They ingest it as a vitamin. Until a recent (2014 reexamination of the basic principle underlying insect metamorphosis, it had been completely overlooked that the Ca2+-pump (SERCA blocker thapsigargin is a sesquiterpenoid that mimics the absence of JH in inducing apoptosis. In our opinion, being in the juvenile state is primarily controlled by endogenous FLS that participate in controlling the activity of Ca2+-ATPases in the sarco(endoplasmic reticulum (SERCAs, not only in insects but in all eukaryotes. Understanding the control mechanisms of being in the juvenile state may boost research not only in developmental biology in general, but also in diseases that develop after the juvenile stage, e.g. Alzheimer’s disease. It may also help to better understand some of the causes of obesity, a syndrome that holometabolous last larval insects severely suffer from, and for which they found a very drastic but efficient solution, namely

  8. Racemic crystals of trolox derivatives compared to their chiral counterparts: Structural studies using solid-state NMR, DFT calculations and X-ray diffraction

    Science.gov (United States)

    Wałejko, P.; Paradowska, K.; Szeleszczuk, Ł.; Wojtulewski, S.; Baj, A.

    2018-03-01

    Trolox C (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) is a water-soluble vitamin E analogue that is available in enantiomeric forms R or S. Enantiomerically pure Trolox 1, its derivatives 2, 3 (R and S enantiomers) and racemic forms 1-3 were studied using solid-state 13C cross-polarisation (CP) magic angle spinning (MAS) NMR (13C CPMAS NMR). Gauge-including projector-augmented wave density functional theory (GIPAW DFT) calculations of the shielding constants supported the assignment of 13C resonances in the solid-state NMR spectra. For the 13C CPMAS NMR spectra of 1, resonances of pure enantiomers were significantly broader than those of the racemic R/S form. In order to explain these effects, five of the available crystal structures were analysed (1R/S, 3R/S, 2S and the newly measured 2R/S and 3S). Cyclic dimers with one R and one S enantiomer linked by two OHsbnd Odbnd C2b hydrogen bonds were formed in 1R/S. Similar hydrogen-bonded dimers were present in 3S but not in 3R/S, in which interactions are water-mediated. A comparison of X-ray diffraction, CPMAS NMR data and the DFT GIPAW calculations of racemic forms and pure enantiomers was conducted for the first time. Our results, particularly the solid-state NMR data, were discussed in relation to Wallach's rule, that the racemic crystal appears as more ordered than its chiral counterpart.

  9. Identification of Cis-Acting Elements on Positive-Strand Subgenomic mRNA Required for the Synthesis of Negative-Strand Counterpart in Bovine Coronavirus

    Directory of Open Access Journals (Sweden)

    Po-Yuan Yeh

    2014-07-01

    Full Text Available It has been demonstrated that, in addition to genomic RNA, sgmRNA is able to serve as a template for the synthesis of the negative-strand [(−-strand] complement. However, the cis-acting elements on the positive-strand [(+-strand] sgmRNA required for (−-strand sgmRNA synthesis have not yet been systematically identified. In this study, we employed real-time quantitative reverse transcription polymerase chain reaction to analyze the cis-acting elements on bovine coronavirus (BCoV sgmRNA 7 required for the synthesis of its (−-strand counterpart by deletion mutagenesis. The major findings are as follows. (1 Deletion of the 5'-terminal leader sequence on sgmRNA 7 decreased the synthesis of the (−-strand sgmRNA complement. (2 Deletions of the 3' untranslated region (UTR bulged stem-loop showed no effect on (−-strand sgmRNA synthesis; however, deletion of the 3' UTR pseudoknot decreased the yield of (−-strand sgmRNA. (3 Nucleotides positioned from −15 to −34 of the sgmRNA 7 3'-terminal region are required for efficient (−-strand sgmRNA synthesis. (4 Nucleotide species at the 3'-most position (−1 of sgmRNA 7 is correlated to the efficiency of (−-strand sgmRNA synthesis. These results together suggest, in principle, that the 5'- and 3'-terminal sequences on sgmRNA 7 harbor cis-acting elements are critical for efficient (−-strand sgmRNA synthesis in BCoV.

  10. Modular expression analysis reveals functional conservation between human Langerhans cells and mouse cross-priming dendritic cells

    OpenAIRE

    Artyomov, Maxim N.; Munk, Adiel; Gorvel, Laurent; Korenfeld, Daniel; Cella, Marina; Tung, Thomas; Klechevsky, Eynav

    2015-01-01

    Characterization of functionally distinct dendritic cell (DC) subsets in mice has fueled interest in whether analogous counterparts exist in humans. Transcriptional modules of coordinately expressed genes were used for defining shared functions between the species. Comparing modules derived from four human skin DC subsets and modules derived from the Immunological Genome Project database for all mouse DC subsets revealed that human Langerhans cells (LCs) and the mouse XCR1+CD8?+CD103+ DCs sha...

  11. Disease features and outcomes in United States lupus patients of Hispanic origin and their Mestizo counterparts in Latin America: a commentary.

    Science.gov (United States)

    Ugarte-Gil, Manuel F; Pons-Estel, Guillermo J; Molineros, Julio; Wojdyla, Daniel; McGwin, Gerald; Nath, Swapan K; Pons-Estel, Bernardo A; Alarcón-Riquelme, Marta; Alarcón, Graciela S

    2016-03-01

    To evaluate disease features and outcomes in two populations with significant Amerindian ancestry. Hispanic patients (from Texas) from the Lupus in Minorities: Nature versus Nurture (LUMINA) cohort and Mestizo patients from the Grupo Latino Americano De Estudio del Lupus or Latin American Group for the Study of Lupus (GLADEL) cohort were included. Disease features and outcomes were evaluated at baseline and last visit. Admixture informative markers of Mestizo Genoma de Lupus Eritematoso Sistémico Network consortium (GENLES) patients and Hispanic LUMINA patients were compared. Univariable analyses were performed using Chi square or Student's t test as appropriate. Multivariable analyses adjusting for possible confounders were carried out using Poisson, logistic or Cox regression models as appropriate. A total of 114 LUMINA and 619 GLADEL patients were included. GLADEL patients had accrued more damage at baseline, but the opposite was the case at last visit. Being from LUMINA was a risk factor for damage accrual, even after adjusting for possible confounders [relative risk (RR) 1.33, 95% CI 1.12, 1.58]. Also, LUMINA patients have a higher risk of mortality than GLADEL patients [hazard ratio (HR) 2.37, 95% CI 1.10, 5.15], having 5-year survival of 85.6% and 94.5%, respectively. In addition, 79 LUMINA patients and 744 Mestizo GENLES patients were evaluated in order to compare genetic ancestry between the two groups; GENLES patients had a higher proportion of European ancestry (48.5% vs 43.3%, P = 0.003) and a lower proportion of Asian ancestry (3.7% vs 4.9%, P = 0.048), but the proportions of Amerindian and African ancestry were comparable in both. USA Hispanic patients seemed to have a poorer prognosis than their counterparts from Latin America, despite having a comparable genetic background. Socioeconomic factors may account for these observations. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights

  12. Speeding Clouds May Reveal Invisible Black Holes

    Science.gov (United States)

    Kohler, Susanna

    2017-07-01

    with these clouds), interaction with supernova remnants (no supernova remnants have been detected toward the clouds), and cloudcloud collisions (such collisions leave other signs, like cavities in the parent cloud, which are not detected here).Masses and velocities of black holes that could create the two high-velocity compact clouds fall above the red and blue lines here. [Takekawa et al. 2017]Revealed on the PlungeAs an alternative explanation, Takekawa and collaborators propose that these two small,speeding cloudswere each created when a massive compact object plunged into a nearby molecular cloud. Since we dont seeany luminous stellar counterparts to the high-velocity compact clouds, this suggests that the responsibleobjects were invisible black holes. As each black hole tore through a molecular cloud, it dragged some of the clouds gas along behind it to form the high-velocity compact cloud.Does this explanation make sense statistically? The authors point out that the number of black holes predicted to silently lurk in the central 30 light-years of the Milky Way is around 10,000. This makes it entirely plausible that we could have caught sight of two of them as they revealed their presence while plunging through molecular clouds.If the authors interpretation is correct, then high-velocity compact clouds provide an excellent opportunity: we can search for these speeding bodiesto potentially discover inactive black holes that would otherwise go undetected.CitationShunya Takekawa et al 2017 ApJL 843 L11. doi:10.3847/2041-8213/aa79ee

  13. A young stellar cluster around a massive protostar revealed by ALMA

    OpenAIRE

    Girart, Josep Miquel; Carrasco-Gonzalez, C.; Anglada, G.; Curiel, S.

    2017-01-01

    Here we present 1.1 mm ALMA observations at a very high angular resolution of a high mass star forming region. The high angular resolution and high dynamic range allows to reveal a young stellar cluster of low mass YSO near a massive protostellar object. Most of the sources detected has no counterpart at other wavelengths (the IR is dominated by the bright emission of the massive/intermediate young stars, which mask the emission of the low mass YSO). A description of the properties of the low...

  14. An analysis of Japan Disaster Medical Assistance Team (J-DMAT) deployments in comparison with those of J-DMAT's counterpart in the United States (US-DMAT).

    Science.gov (United States)

    Fuse, Akira; Yokota, Hiroyuki

    2010-12-01

    Lessons learned from the Great Hanshin-Awaji earthquake of 1995 underscored the necessity of establishing Disaster Medical Assistance Teams (DMATs) in Japan, and in 2005, the Japanese government's Central Disaster Prevention Council revised its Basic Disaster Management Plan to include full deployment of DMATs in disaster areas. Defining a DMAT as a trained, mobile, self-contained medical team that can act in the acute phase of a disaster (48 to 72 hours after its occurrence) to provide medical treatment in the devastated area, the revised plan called for the training of DMAT personnel for rapid deployment to any area of the country hit by a disaster. This paper presents descriptive data on the number and types of missions carried out by Japan DMAT (J-DMAT) in its first 5 years, and clarifies how J-DMAT differs from its counterpart in the United States (US-DMAT). The DMAT that the present authors belong to has been deployed for 2 natural disasters and 1 man-made disaster, and the operations carried out during these deployments are analyzed. Reports on J-DMAT activities published from 2004 through 2009 by the Japanese Association for Disaster Medicine are also included in the analysis. After training courses for J-DMAT personnel started in fiscal 2004, J-DMATs were deployed for 8 disasters in a period of 4 years. Five of these were natural disasters, and 3 man-made. Of the 5 natural disasters, 3 were earthquakes, and of the 3 man-made disasters, 2 were derailment accidents. Unlike in the United States, where hurricanes and floods account for the greatest number of DMAT deployments, earthquakes cause the largest number of disasters in Japan. Because Japan is small in comparison with the US (Japan has about 1/25 the land area of the US), most J-DMATs head for devastated areas by car from their respective hospitals. This is one reason why J-DMATs are smaller and more agile than US-DMATs. Another difference is that J-DMATs' activities following earthquakes involve

  15. Influence of macrocyclic chelators on the targeting properties of (68Ga-labeled synthetic affibody molecules: comparison with (111In-labeled counterparts.

    Directory of Open Access Journals (Sweden)

    Joanna Strand

    Full Text Available Affibody molecules are a class of small (7 kDa non-immunoglobulin scaffold-based affinity proteins, which have demonstrated substantial potential as probes for radionuclide molecular imaging. The use of positron emission tomography (PET would further increase the resolution and quantification accuracy of Affibody-based imaging. The rapid in vivo kinetics of Affibody molecules permit the use of the generator-produced radionuclide (68Ga (T1/2=67.6 min. Earlier studies have demonstrated that the chemical nature of chelators has a substantial influence on the biodistribution properties of Affibody molecules. To determine an optimal labeling approach, the macrocyclic chelators 1,4,7,10-tetraazacylododecane-1,4,7,10-tetraacetic acid (DOTA, 1,4,7-triazacyclononane-N,N,N-triacetic acid (NOTA and 1-(1,3-carboxypropyl-1,4,7- triazacyclononane-4,7-diacetic acid (NODAGA were conjugated to the N-terminus of the synthetic Affibody molecule ZHER2:S1 targeting HER2. Affibody molecules were labeled with (68Ga, and their binding specificity and cellular processing were evaluated. The biodistribution of (68Ga-DOTA-ZHER2:S1, (68Ga-NOTA-ZHER2:S1 and (68Ga-NODAGA-ZHER2:S1, as well as that of their (111In-labeled counterparts, was evaluated in BALB/C nu/nu mice bearing HER2-expressing SKOV3 xenografts. The tumor uptake for (68Ga-DOTA-ZHER2:S1 (17.9 ± 0.7%IA/g was significantly higher than for both (68Ga-NODAGA-ZHER2:S1 (16.13 ± 0.67%IA/g and (68Ga-NOTA-ZHER2:S1 (13 ± 3%IA/g at 2 h after injection. (68Ga-NODAGA-ZHER2:S1 had the highest tumor-to-blood ratio (60 ± 10 in comparison with both (68Ga-DOTA-ZHER2:S1 (28 ± 4 and (68Ga-NOTA-ZHER2:S1 (42 ± 11. The tumor-to-liver ratio was also higher for (68Ga-NODAGA-ZHER2:S1 (7 ± 2 than the DOTA and NOTA conjugates (5.5 ± 0.6 vs.3.3 ± 0.6. The influence of chelator on the biodistribution and targeting properties was less pronounced for (68Ga than for (111In. The results of this study demonstrate that macrocyclic

  16. Neuronal protein gene product 9.5 (IEF SSP 6104) is expressed in cultured human MRC-5 fibroblasts of normal origin and is strongly down-regulated in their SV40 transformed counterparts

    DEFF Research Database (Denmark)

    Honoré, B; Rasmussen, H H; Vandekerckhove, J

    1991-01-01

    Neuronal protein gene product 9.5 (PGP 9.5) most likely identical to ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) has been reported to be expressed almost exclusively in neuronal and neuroendocrine tissues. By two-dimensional (2D) immunoblotting, comigration and microsequencing...... is expressed at high levels in quiescent and proliferating cultured normal fibroblasts and is strongly down-regulated (about 10 times) in their transformed counterparts. Udgivelsesdato: 1991-Mar-25...

  17. The Punta del Este Suspect Terrane: a possible counterpart in Eastern Uruguay of the Namaqua Complex and Gariep Belt in Western Africa

    International Nuclear Information System (INIS)

    Preciozzi, F.; Basei, M.; Peel, E.

    2005-01-01

    two tectono-stratigraphic sets with the eastern portion occupied by parautochthonous units of a passive continental margin (Port Nolloth Zone) and a western allochthonous domain (Marmora Terrane). The evidences of blueschist facies metamorphism, countless times referred in the literature (Kröner, 1974; Porada, 1979), have been recently ruled out by Frimmel and Hartnady (1992). The sedimentation period of the Gariep Group is attributed to the Neoproterozoic because it lays discordantly on the rhyolite units (Ross Pinah Formation) dated by the single zircon evaporation technique as 735Ma (Frimmel, 1995). Meert §& Van der Voo (1994) correlated diamictite intercalations, probably of age between 580 and 560 Ma, in the upper portion of the Gariep Group with the glacial deposits of Vendian age. The northeastern portion of the Gariep Group is covered by not metamorphosed sediments of the Nama Group. In the South-American counterpart, that is, the South-Brazilian region and the Uruguayan territory, an old western domain is observed The Central Domain is represented by the Rio de La Plata Craton (sensus Almeida et al.,1973) ,by de Nico Perez Terrane (Bossi et al.,1992 ;Valentines Block,PavasTerrane (Preciozzi et al.,1979) and the Rivera granitic-gneissic complex ..All of them were generated or intensively reworked during the Neoproterozoic, distributed along its eastern border and as a whole organised in the NE-SW direction. In these domain, a granitic-migmatitic infrastructure and sedimentary basins and low- to medium metamorphic grade covers predominate, related to the Lavalleja-supergroup and Zanja del Cerro Grande Group The Rocha formation is developed as a metasedimentary cover in the Punta del Este Terrane,being associated to the Atlantic Domain. Geochronologic studies recently performed in the southeastern portion of Uruguay allowed the identification of igneous rocks with U-Pb ages in zircons ranging from 650 to 1000Ma. These ages, added to the geological

  18. Decision Making and Revealed Preference

    DEFF Research Database (Denmark)

    de la Rosa, Leonidas Enrique

    If our decision-making processes are to some extent shaped by evolutionary pressures and our environment is different from that to which we adapted, some of our choices will not be in our best interest. But revealed preference is the only tool that we have so far to conduct a normative analysis...

  19. Revealing and Concealing in Antiquity

    DEFF Research Database (Denmark)

    Secrecy and the act of concealing and revealing knowledge effectually segregate the initiated and the uninitiated. The act of sharing or hiding knowledge plays a central role in all human relations private or public, political or religious. This volume explores the concept of secrecy and its...

  20. Revealed preference with limited consideration

    NARCIS (Netherlands)

    Demuynck, T.; Seel, C.

    2014-01-01

    We derive revealed preference tests for models where individuals use consideration sets to simplify their consumption problem. Our basic test provides necessary and sufficient conditions for consistency of observed choices with the existence of consideration set restrictions. The same conditions can

  1. Reversible Activation of Halophilic β-lactamase from Methanol-Induced Inactive Form: Contrast to Irreversible Inactivation of Non-Halophilic Counterpart.

    Science.gov (United States)

    Tokunaga, Hiroko; Maeda, Junpei; Arakawa, Tsutomu; Tokunaga, Masao

    2017-06-01

    Effects of a water-miscible organic solvent, methanol, on the structure and activity of halophilic β-lactamase derived from Chromohalobacter sp.560 (HaBla), were investigated by means of circular dichroism (CD) measurement and enzymatic activity determination. Beta-lactamase activity was enhanced about 1.2-fold in the presence of 10-20% methanol. CD measurement of HaBla revealed different structures depending on the methanol concentration: native-like active form (Form I) in 10-20% methanol and methanol-induced inactive form at higher concentration (Form II in 40-60% and Form III in 75-80% methanol). Incubation of HaBla with 40% methanol led to the complete loss of activity within ~80 min accompanied by the formation of Form II, whose activity was recovered promptly up to ~80% of full activity upon dilution of the methanol concentration to 10%. In addition, when the protein concentration was sufficiently high (e.g., 0.7 mg/ml), HaBla activity of Form III in 75% methanol could be recovered in the same way (with slightly slower recovery rate), upon dilution of the methanol concentration. In contrast, non-halophilic β-lactamase from Escherichia coli K12 strain MG1655 (EcBla) was irreversibly denatured in the presence of 40% methanol. HaBla showed remarkable ability to renature from the methanol-induced inactive states.

  2. N-Terminal Domains in Two-Domain Proteins Are Biased to Be Shorter and Predicted to Fold Faster Than Their C-Terminal Counterparts

    Directory of Open Access Journals (Sweden)

    Etai Jacob

    2013-04-01

    Full Text Available Computational analysis of proteomes in all kingdoms of life reveals a strong tendency for N-terminal domains in two-domain proteins to have shorter sequences than their neighboring C-terminal domains. Given that folding rates are affected by chain length, we asked whether the tendency for N-terminal domains to be shorter than their neighboring C-terminal domains reflects selection for faster-folding N-terminal domains. Calculations of absolute contact order, another predictor of folding rate, provide additional evidence that N-terminal domains tend to fold faster than their neighboring C-terminal domains. A possible explanation for this bias, which is more pronounced in prokaryotes than in eukaryotes, is that faster folding of N-terminal domains reduces the risk for protein aggregation during folding by preventing formation of nonnative interdomain interactions. This explanation is supported by our finding that two-domain proteins with a shorter N-terminal domain are much more abundant than those with a shorter C-terminal domain.

  3. Differential impacts of social support on mental health: A comparison study of Chinese rural-to-urban migrant adolescents and their urban counterparts in Beijing, China.

    Science.gov (United States)

    Zhuang, Xiao Yu; Wong, Daniel Fu Keung

    2017-02-01

    The number of internal migrant children in China has reached 35.8 million by the end of 2010. Previous studies revealed inconsistent findings regarding the mental health status of rural-to-urban migrant adolescents, as well as the impact of peer, teacher and parental support on the mental health of Chinese adolescent migrants. Using a comparative approach, this study attempted to compare the mental health status between migrant and urban-born adolescents and to clarify the specific roles of different sources of social support in the mental health of migrant and urban adolescents. A cross-sectional survey using a cluster convenience sampling strategy was performed in Beijing, China. A structured questionnaire was filled out by 368 rural-to-urban migrant adolescents and 325 urban-born adolescents. A significant difference was found only for positive affect (PA) but not for negative affect (NA) between the two groups, favouring the urban-born adolescents. Social support from all the three sources were all predictive of PA among rural-to-urban migrant adolescents, while only peer support contributed to PA among urban-born adolescents. Unexpectedly, teachers' support contributed to an increase in NA among urban-born adolescents. The findings contribute to understanding of the mental health status of migrant adolescents in China and the differential impact of the various sources of social support on migrant and urban-born adolescents. Also the findings may inform the development of mental health services and programmes that can potentially benefit a large number of internal migrant adolescents in China.

  4. FEATURES OF EQUIVALENCE OF RUSSIAN WORD «НЕДВИЖИМОСТЬ» (“REAL ESTATE” TO ITS ENGLISH COUNTERPARTS

    Directory of Open Access Journals (Sweden)

    Kravchuk, Y.S.

    2017-03-01

    Full Text Available The following article, prepared using dictionary materials, is related to the issues of intercultural communication. It considers historical genesis of written records of the word «недвижимость» (“real estate” in the English and Russian languages. We analysed the issue of equivalence of the Russian word «недвижимость» (“real estate” and its English counterparts and suggested an approach to understanding equivalence under the conditions of inhomogeneous expressiveness of the researched word in different semantic fields of the Russian and English languages.

  5. Transparency masters for mathematics revealed

    CERN Document Server

    Berman, Elizabeth

    1980-01-01

    Transparency Masters for Mathematics Revealed focuses on master diagrams that can be used for transparencies for an overhead projector or duplicator masters for worksheets. The book offers information on a compilation of master diagrams prepared by John R. Stafford, Jr., audiovisual supervisor at the University of Missouri at Kansas City. Some of the transparencies are designed to be shown horizontally. The initial three masters are number lines and grids that can be used in a mathematics course, while the others are adaptations of text figures which are slightly altered in some instances. The

  6. To Reveal Thy Heart Perchance to Reveal the World

    Directory of Open Access Journals (Sweden)

    Robert B. Faux

    2005-05-01

    Full Text Available Ronald PELIAS, a professor of speech communications, employs a variety of writing methods as examples of alternative ways to do research and to share with the reader a seldom seen and seldom considered aspect of academic life: Heart. In the early chapters of the book, PELIAS sets out to establish a way to place his Heart in the foreground; baring his emotional vulnerability, his humanness, his being in the world. Later chapters of the book encompass an autoethnographic study of academic life in which the previously revealed Heart is placed in context. In this review essay I discuss PELIAS' book in relation to the larger literature on autoethnography and subjectivist research; I follow this by discussing the need for and usefulness of such alternative methods using PELIAS' autoethnography of academic life as a context. URN: urn:nbn:de:0114-fqs050279

  7. Searching the Gamma-Ray Sky for Counterparts to Gravitational Wave Sources Fermi Gamma-Ray Burst Monitor and Large Area Telescope Observations of LVT151012 and GW151226

    Science.gov (United States)

    Racusin, J. L.; Burns, E.; Goldstein, A.; Connaughton, V.; Wilson-Hodge, C. A.; Jenke, P.; Blackburn, L.; Briggs, M. S.; Broida, J.; Camp, J.; hide

    2017-01-01

    We present the Fermi Gamma-ray Burst Monitor (GBM) and Large Area Telescope (LAT) observations of the LIGO binary black hole merger event GW151226 and candidate LVT151012. At the time of the LIGO triggers on LVT151012 and GW151226, GBM was observing 68% and 83% of the localization regions, and LAT was observing 47% and 32%, respectively. No candidate electromagnetic counterparts were detected by either the GBM or LAT. We present a detailed analysis of the GBM and LAT data over a range of timescales from seconds to years, using automated pipelines and new techniques for characterizing the flux upper bounds across large areas of the sky. Due to the partial GBM and LAT coverage of the large LIGO localization regions at the trigger times for both events, differences in source distances and masses, as well as the uncertain degree to which emission from these sources could be beamed, these non-detections cannot be used to constrain the variety of theoretical models recently applied to explain the candidate GBM counterpart to GW150914.

  8. SEARCHING THE GAMMA-RAY SKY FOR COUNTERPARTS TO GRAVITATIONAL WAVE SOURCES: FERMI GAMMA-RAY BURST MONITO R AND LARGE AREA TELESCOPE OBSERVATIONS OF LVT151012 AND GW151226

    Energy Technology Data Exchange (ETDEWEB)

    Racusin, J. L.; Camp, J.; Singer, L. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Burns, E. [Physics Dept, University of Alabama in Huntsville, 320 Sparkman Dr., Huntsville, AL 35805 (United States); Goldstein, A.; Connaughton, V.; Littenberg, T.; Cleveland, W. [Universities Space Research Association, 320 Sparkman Dr. Huntsville, AL 35806 (United States); Wilson-Hodge, C. A.; Hui, C. M. [Astrophysics Office, ZP12, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Jenke, P.; Briggs, M. S.; Bhat, P. N. [CSPAR, University of Alabama in Huntsville, 320 Sparkman Dr., Huntsville, AL 35805 (United States); Blackburn, L. [LIGO, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Broida, J.; Christensen, N. [Physics and Astronomy, Carleton College, MN 55057 (United States); Shawhan, P. [Department of Physics, University of Maryland, College Park, MD 20742 (United States); Veitch, J. [University of Birmingham, Birmingham B15 2TT (United Kingdom); Fitzpatrick, G. [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); Gibby, M. H. [Jacobs Technology, Inc., Huntsville, AL (United States); Collaboration: Fermi LAT Collaboration; and others

    2017-01-20

    We present the Fermi Gamma-ray Burst Monitor (GBM) and Large Area Telescope (LAT) observations of the LIGO binary black hole merger event GW151226 and candidate LVT151012. At the time of the LIGO triggers on LVT151012 and GW151226, GBM was observing 68% and 83% of the localization regions, and LAT was observing 47% and 32%, respectively. No candidate electromagnetic counterparts were detected by either the GBM or LAT. We present a detailed analysis of the GBM and LAT data over a range of timescales from seconds to years, using automated pipelines and new techniques for characterizing the flux upper bounds across large areas of the sky. Due to the partial GBM and LAT coverage of the large LIGO localization regions at the trigger times for both events, differences in source distances and masses, as well as the uncertain degree to which emission from these sources could be beamed, these non-detections cannot be used to constrain the variety of theoretical models recently applied to explain the candidate GBM counterpart to GW150914.

  9. Plan competitions reveal entrepreneurial talent

    Energy Technology Data Exchange (ETDEWEB)

    Madison, Alison L.

    2011-05-15

    Monthly economic diversity column for Tri-City Herald business section. Excerpt below: There’s something to be said for gaining valuable real-world experience in a structured, nurturing environment. Take for instance learning to scuba dive in the comfort of my resort pool rather than immediately hanging out with sharks while I figure out little things like oxygen tanks and avoiding underwater panic attacks. Likewise, graduate students are getting some excellent, supportive real-world training through university business plan competitions. These competitions are places where smart minds, new technologies, months of preparation and coaching, and some healthy pre-presentation jitters collide to reveal not only solid new business ideas, but also some promising entrepreneurial talent. In fact, professionals from around our region descend upon college campuses every spring to judge these events, which help to bridge the gap between academics and the real technology and business-driven economy.

  10. Communication Games Reveal Preparation Contextuality

    Science.gov (United States)

    Hameedi, Alley; Tavakoli, Armin; Marques, Breno; Bourennane, Mohamed

    2017-12-01

    A communication game consists of distributed parties attempting to jointly complete a task with restricted communication. Such games are useful tools for studying limitations of physical theories. A theory exhibits preparation contextuality whenever its predictions cannot be explained by a preparation noncontextual model. Here, we show that communication games performed in operational theories reveal the preparation contextuality of that theory. For statistics obtained in a particular family of communication games, we show a direct correspondence with correlations in spacelike separated events obeying the no-signaling principle. Using this, we prove that all mixed quantum states of any finite dimension are preparation contextual. We report on an experimental realization of a communication game involving three-level quantum systems from which we observe a strong violation of the constraints of preparation noncontextuality.

  11. Communication Games Reveal Preparation Contextuality.

    Science.gov (United States)

    Hameedi, Alley; Tavakoli, Armin; Marques, Breno; Bourennane, Mohamed

    2017-12-01

    A communication game consists of distributed parties attempting to jointly complete a task with restricted communication. Such games are useful tools for studying limitations of physical theories. A theory exhibits preparation contextuality whenever its predictions cannot be explained by a preparation noncontextual model. Here, we show that communication games performed in operational theories reveal the preparation contextuality of that theory. For statistics obtained in a particular family of communication games, we show a direct correspondence with correlations in spacelike separated events obeying the no-signaling principle. Using this, we prove that all mixed quantum states of any finite dimension are preparation contextual. We report on an experimental realization of a communication game involving three-level quantum systems from which we observe a strong violation of the constraints of preparation noncontextuality.

  12. The chemistry of plutonium revealed

    International Nuclear Information System (INIS)

    Connick, R.E.

    1990-01-01

    In 1941 one goal of the Manhattan Project was to unravel the chemistry of the synthetic element plutonium as rapidly as possible. Important insights were obtained from tracer experiments, but the full complexity of plutonium chemistry was not revealed until macroscopic amounts (milligrams) became available. Because processes for separation from fission products were aqueous solution based, such solution chemistry was emphasized, particularly precipitation and oxidation-reduction behavior. The latter turned out to be unusually intricate when it was discovered that two more oxidation states existed in aqueous solution than had previously been suspected. Further, it was found that an equilibrium was rapidly established among the four aqueous oxidation states while at the same time any three were not in equilibrium. These and other observations made while doing a crash study of a previously unknown element will be reported

  13. Revealing ontological commitments by magic.

    Science.gov (United States)

    Griffiths, Thomas L

    2015-03-01

    Considering the appeal of different magical transformations exposes some systematic asymmetries. For example, it is more interesting to transform a vase into a rose than a rose into a vase. An experiment in which people judged how interesting they found different magic tricks showed that these asymmetries reflect the direction a transformation moves in an ontological hierarchy: transformations in the direction of animacy and intelligence are favored over the opposite. A second and third experiment demonstrated that judgments of the plausibility of machines that perform the same transformations do not show the same asymmetries, but judgments of the interestingness of such machines do. A formal argument relates this sense of interestingness to evidence for an alternative to our current physical theory, with magic tricks being a particularly pure source of such evidence. These results suggest that people's intuitions about magic tricks can reveal the ontological commitments that underlie human cognition. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Hubble Images Reveal Jupiter's Auroras

    Science.gov (United States)

    1996-01-01

    These images, taken by the Hubble Space Telescope, reveal changes in Jupiter's auroral emissions and how small auroral spots just outside the emission rings are linked to the planet's volcanic moon, Io. The images represent the most sensitive and sharply-detailed views ever taken of Jovian auroras.The top panel pinpoints the effects of emissions from Io, which is about the size of Earth's moon. The black-and-white image on the left, taken in visible light, shows how Io and Jupiter are linked by an invisible electrical current of charged particles called a 'flux tube.' The particles - ejected from Io (the bright spot on Jupiter's right) by volcanic eruptions - flow along Jupiter's magnetic field lines, which thread through Io, to the planet's north and south magnetic poles. This image also shows the belts of clouds surrounding Jupiter as well as the Great Red Spot.The black-and-white image on the right, taken in ultraviolet light about 15 minutes later, shows Jupiter's auroral emissions at the north and south poles. Just outside these emissions are the auroral spots. Called 'footprints,' the spots are created when the particles in Io's 'flux tube' reach Jupiter's upper atmosphere and interact with hydrogen gas, making it fluoresce. In this image, Io is not observable because it is faint in the ultraviolet.The two ultraviolet images at the bottom of the picture show how the auroral emissions change in brightness and structure as Jupiter rotates. These false-color images also reveal how the magnetic field is offset from Jupiter's spin axis by 10 to 15 degrees. In the right image, the north auroral emission is rising over the left limb; the south auroral oval is beginning to set. The image on the left, obtained on a different date, shows a full view of the north aurora, with a strong emission inside the main auroral oval.The images were taken by the telescope's Wide Field and Planetary Camera 2 between May 1994 and September 1995.This image and other images and data

  15. A parts list for fungal cellulosomes revealed by comparative genomics

    Energy Technology Data Exchange (ETDEWEB)

    Haitjema, Charles H.; Gilmore, Sean P.; Henske, John K.; Solomon, Kevin V.; de Groot, Randall; Kuo, Alan; Mondo, Stephen J.; Salamov, Asaf A.; LaButti, Kurt; Zhao, Zhiying; Chiniquy, Jennifer; Barry, Kerrie; Brewer, Heather M.; Purvine, Samuel O.; Wright, Aaron T.; Hainaut, Matthieu; Boxma, Brigitte; van Alen, Theo; Hackstein, Johannes H. P.; Henrissat, Bernard; Baker, Scott E.; Grigoriev, Igor V.; O' Malley, Michelle A.

    2017-05-26

    Cellulosomes are large, multi-protein complexes that tether plant biomass degrading enzymes together for improved hydrolysis1. These complexes were first described in anaerobic bacteria where species specific dockerin domains mediate assembly of enzymes onto complementary cohesin motifs interspersed within non-catalytic protein scaffolds1. The versatile protein assembly mechanism conferred by the bacterial cohesin-dockerin interaction is now a standard design principle for synthetic protein-scale pathways2,3. For decades, analogous structures have been reported in the early branching anaerobic fungi, which are known to assemble by sequence divergent non-catalytic dockerin domains (NCDD)4. However, the enzyme components, modular assembly mechanism, and functional role of fungal cellulosomes remain unknown5,6. Here, we describe the comprehensive set of proteins critical to fungal cellulosome assembly, including novel, conserved scaffolding proteins unique to the Neocallimastigomycota. High quality genomes of the anaerobic fungi Anaeromyces robustus, Neocallimastix californiae and Piromyces finnis were assembled with long-read, single molecule technology to overcome their repeat-richness and extremely low GC content. Genomic analysis coupled with proteomic validation revealed an average 320 NCDD-containing proteins per fungal strain that were overwhelmingly carbohydrate active enzymes (CAZymes), with 95 large fungal scaffoldins identified across 4 genera that contain a conserved amino acid sequence repeat that binds to NCDDs. Fungal dockerin and scaffoldin domains have no similarity to their bacterial counterparts, yet several catalytic domains originated via horizontal gene transfer with gut bacteria. Though many catalytic domains are shared with bacteria, the biocatalytic activity of anaerobic fungi is expanded by the inclusion of GH3, GH6, and GH45 enzymes in the enzyme complexes. Collectively, these findings suggest that the fungal cellulosome is an evolutionarily

  16. Stability in the composition equivalence of grain from insect-protected maize and seed from glyphosate-tolerant soybean to conventional counterparts over multiple seasons, locations, and breeding germplasms.

    Science.gov (United States)

    Zhou, Jie; Harrigan, George G; Berman, Kristina H; Webb, Elizabeth G; Klusmeyer, Tim H; Nemeth, Margaret A

    2011-08-24

    Insect-protected maize MON 810 and Roundup Ready soybean 40-3-2 represent major milestones in the adoption of genetically modified (GM) crops to enhance agricultural productivity. This study provides an assessment of the compositional stability of these products over multiple seasons, multiple germplasms, and diverse geographies encompassing North, Central, and South America and Europe. The compositional assessment evaluated levels of proximates in MON 810 and proximates, antinutrients, and isoflavones in 40-3-2. The means and range values for component levels in the GM crops and their conventional comparators were consistently similar to each other within each corresponding year from 2000 to 2009. To our knowledge, this study represents the first meta-analysis of comparative composition assessments of GM products. This approach, combined with graphical approaches, provided an effective summary of the overall data set and confirmed the continued compositional equivalence of these important crops to their conventional counterparts over time.

  17. Entropic counterpart of perturbative Einstein equation

    Science.gov (United States)

    Bhattacharya, Jyotirmoy; Takayanagi, Tadashi

    2013-10-01

    Entanglement entropy in a field theory, with a holographic dual, may be viewed as a quantity which encodes the diffeomorphism invariant bulk gravity dynamics. This, in particular, indicates that the bulk Einstein equations would imply some constraints for the boundary entanglement entropy. In this paper we focus on the change in entanglement entropy, for small but arbitrary fluctuations about a given state, and analyze the constraints imposed on it by the perturbative Einstein equations, linearized about the corresponding bulk state. Specifically, we consider linear fluctuations about BTZ black hole in 3 dimension, pure AdS and AdS Schwarzschild black holes in 4 dimensions and obtain a diffeomorphism invariant reformulation of linearized Einstein equation in terms of holographic entanglement entropy. We will also show that entanglement entropy for boosted subsystems provides the information about all the components of the metric with a time index.

  18. Entropic Counterpart of Perturbative Einstein Equation

    OpenAIRE

    Bhattacharya, Jyotirmoy; Takayanagi, Tadashi

    2013-01-01

    Entanglement entropy in a field theory, with a holographic dual, may be viewed as a quantity which encodes the diffeomorphism invariant bulk gravity dynamics. This, in particular, indicates that the bulk Einstein equations would imply some constraints for the boundary entanglement entropy. In this paper we focus on the change in entanglement entropy, for small but arbitrary fluctuations about a given state, and analyze the constraints imposed on it by the perturbative Einstein equations, line...

  19. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. VI. Radio Constraints on a Relativistic Jet and Predictions for Late-time Emission from the Kilonova Ejecta

    Science.gov (United States)

    Alexander, K. D.; Berger, E.; Fong, W.; Williams, P. K. G.; Guidorzi, C.; Margutti, R.; Metzger, B. D.; Annis, J.; Blanchard, P. K.; Brout, D.; Brown, D. A.; Chen, H.-Y.; Chornock, R.; Cowperthwaite, P. S.; Drout, M.; Eftekhari, T.; Frieman, J.; Holz, D. E.; Nicholl, M.; Rest, A.; Sako, M.; Soares-Santos, M.; Villar, V. A.

    2017-10-01

    We present Very Large Array (VLA) and Atacama Large Millimeter/submillimeter Array (ALMA) radio observations of GW170817, the first Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo gravitational wave (GW) event from a binary neutron star merger and the first GW event with an electromagnetic (EM) counterpart. Our data include the first observations following the discovery of the optical transient at both the centimeter (13.7 hr post-merger) and millimeter (2.41 days post-merger) bands. We detect faint emission at 6 GHz at 19.47 and 39.23 days after the merger, but not in an earlier observation at 2.46 days. We do not detect cm/mm emission at the position of the optical counterpart at frequencies of 10-97.5 GHz at times ranging from 0.6 to 30 days post-merger, ruling out an on-axis short gamma-ray burst (SGRB) for energies ≳ {10}48 erg. For fiducial SGRB parameters, our limits require an observer viewer angle of ≳20°. The radio and X-ray data can be jointly explained as the afterglow emission from an SGRB with a jet energy of ˜ {10}49{--}{10}50 erg that exploded in a uniform density environment with n˜ {10}-4{--}{10}-2 cm-3, viewed at an angle of ˜20°-40° from the jet axis. Using the results of our light curve and spectral modeling, in conjunction with the inference of the circumbinary density, we predict the emergence of late-time radio emission from the deceleration of the kilonova (KN) ejecta on a timescale of ˜5-10 years that will remain detectable for decades with next-generation radio facilities, making GW170817 a compelling target for long-term radio monitoring.

  20. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. VI. Radio Constraints on a Relativistic Jet and Predictions for Late-time Emission from the Kilonova Ejecta

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, K. D.; Berger, E.; Fong, W.; Williams, P. K. G.; Guidorzi, C.; Margutti, R.; Metzger, B. D.; Annis, J.; Blanchard, P. K.; Brout, D.; Brown, D. A.; Chen, H. -Y.; Chornock, R.; Cowperthwaite, P. S.; Drout, M.; Eftekhari, T.; Frieman, J.; Holz, D. E.; Nicholl, M.; Rest, A.; Sako, M.; Soares-Santos, M.; Villar, V. A.

    2017-10-16

    We present Very Large Array (VLA) and Atacama Large Millimeter/sub-millimeter Array ALMA radio observations of GW\\,170817, the first Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo gravitational wave (GW) event from a binary neutron star merger and the first GW event with an electromagnetic (EM) counterpart. Our data include the first observations following the discovery of the optical transient at both the centimeter ($13.7$ hours post merger) and millimeter ($2.41$ days post merger) bands. We detect faint emission at 6 GHz at 19.47 and 39.23 days after the merger, but not in an earlier observation at 2.46 d. We do not detect cm/mm emission at the position of the optical counterpart at frequencies of 10-97.5 GHz at times ranging from 0.6 to 30 days post merger, ruling out an on-axis short gamma-ray burst (SGRB) for energies $\\gtrsim 10^{48}$ erg. For fiducial SGRB parameters, our limits require an observer viewer angle of $\\gtrsim 20^{\\circ}$. The radio and X-ray data can be jointly explained as the afterglow emission from an SGRB with a jet energy of $\\sim 10^{49}-10^{50}$ erg that exploded in a uniform density environment with $n\\sim 10^{-4}-10^{-2}$ cm$^{-3}$, viewed at an angle of $\\sim 20^{\\circ}-40^{\\circ}$ from the jet axis. Using the results of our light curve and spectral modeling, in conjunction with the inference of the circumbinary density, we predict the emergence of late-time radio emission from the deceleration of the kilonova (KN) ejecta on a timescale of $\\sim 5-10$ years that will remain detectable for decades with next-generation radio facilities, making GW\\,170817 a compelling target for long-term radio monitoring.

  1. Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury.

    Science.gov (United States)

    Chaboub, Lesley S; Manalo, Jeanne M; Lee, Hyun Kyoung; Glasgow, Stacey M; Chen, Fengju; Kawasaki, Yoshihiro; Akiyama, Tetsu; Kuo, Chay T; Creighton, Chad J; Mohila, Carrie A; Deneen, Benjamin

    2016-11-23

    Lineage development is a stepwise process, governed by stage-specific regulatory factors and associated markers. Astrocytes are one of the principle cell types in the CNS and the stages associated with their development remain very poorly defined. To identify these stages, we performed gene-expression profiling on astrocyte precursor populations in the spinal cord, identifying distinct patterns of gene induction during their development that are strongly correlated with human astrocytes. Validation studies identified a new cohort of astrocyte-associated genes during development and demonstrated their expression in reactive astrocytes in human white matter injury (WMI). Functional studies on one of these genes revealed that mice lacking Asef exhibited impaired astrocyte differentiation during development and repair after WMI, coupled with compromised blood-brain barrier integrity in the adult CNS. These studies have identified distinct stages of astrocyte lineage development associated with human WMI and, together with our functional analysis of Asef, highlight the parallels between astrocyte development and their reactive counterparts associated with injury. Astrocytes play a central role in CNS function and associated diseases. Yet the mechanisms that control their development remain poorly defined. Using the developing mouse spinal cord as a model system, we identify molecular changes that occur in developing astrocytes. These molecular signatures are strongly correlated with human astrocyte expression profiles and validation in mouse spinal cord identifies a host of new genes associated with the astrocyte lineage. These genes are present in reactive astrocytes in human white matter injury, and functional studies reveal that one of these genes, Asef, contributes to reactive astrocyte responses after injury. These studies identify distinct stages of astrocyte lineage development and highlight the parallels between astrocyte development and their reactive

  2. Puerto Rico Revealed Preference Survey Data 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Revealed preference models provide insights into recreational angler behavior and the economic value of recreational fishing trips. Revealed preference data is...

  3. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. IV. Detection of Near-infrared Signatures of r-process Nucleosynthesis with Gemini-South

    Science.gov (United States)

    Chornock, R.; Berger, E.; Kasen, D.; Cowperthwaite, P. S.; Nicholl, M.; Villar, V. A.; Alexander, K. D.; Blanchard, P. K.; Eftekhari, T.; Fong, W.; Margutti, R.; Williams, P. K. G.; Annis, J.; Brout, D.; Brown, D. A.; Chen, H.-Y.; Drout, M. R.; Farr, B.; Foley, R. J.; Frieman, J. A.; Fryer, C. L.; Herner, K.; Holz, D. E.; Kessler, R.; Matheson, T.; Metzger, B. D.; Quataert, E.; Rest, A.; Sako, M.; Scolnic, D. M.; Smith, N.; Soares-Santos, M.

    2017-10-01

    We present a near-infrared spectral sequence of the electromagnetic counterpart to the binary neutron star merger GW170817 detected by Advanced Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo. Our data set comprises seven epochs of J+H spectra taken with FLAMINGOS-2 on Gemini-South between 1.5 and 10.5 days after the merger. In the initial epoch, the spectrum is dominated by a smooth blue continuum due to a high-velocity, lanthanide-poor blue kilonova component. Starting the following night, all of the subsequent spectra instead show features that are similar to those predicted in model spectra of material with a high concentration of lanthanides, including spectral peaks near 1.07 and 1.55 μm. Our fiducial model with 0.04 M ⊙ of ejecta, an ejection velocity of v = 0.1c, and a lanthanide concentration of X lan = 10-2 provides a good match to the spectra taken in the first five days, although it over-predicts the late-time fluxes. We also explore models with multiple fitting components, in each case finding that a significant abundance of lanthanide elements is necessary to match the broad spectral peaks that we observe starting at 2.5 days after the merger. These data provide direct evidence that binary neutron star mergers are significant production sites of even the heaviest r-process elements.

  4. Crystal structure and Hirshfeld surface analysis of 1-carboxy-2-(3,4-dihydroxyphenylethan-1-aminium chloride 2-ammonio-3-(3,4-dihydroxyphenylpropanoate: a new polymorph of l-dopa HCl and isotypic with its bromide counterpart

    Directory of Open Access Journals (Sweden)

    Perumal Kathiravan

    2016-11-01

    Full Text Available The title molecular salt, C9H12NO4+·Cl−·C9H11NO4, is isotypic with that of the bromide counterpart [Kathiravan et al. (2016. Acta Cryst. E72, 1544–1548]. The title salt is a second monoclinic polymorph of the l-dopa HCl structure reported earlier in the monoclinic space group P21 [Jandacek & Earle (1971. Acta Cryst. B27, 841–845; Mostad & Rømming (1974. Acta Chemica Scand. B28, 1161–1168]. In the title compound, monoclinic space group I2, one of the dopa molecules has a positive charge with a protonated α-amino group and the α-carboxylic acid group uncharged, while the second dopa molecule has a neutral charge, the α-amino group is protonated and the α-carboxylic acid is deprotonated. In the previously reported form, a single dopa molecule is observed in which the α-amino group is protonated and the α-carboxylic acid group is uncharged. The invariant and variations of various types of intermolecular interactions present in these two forms of dopa HCl structures are discussed with the aid of two-dimensional fingerprint plots.

  5. The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/Virgo GW170817. IV. Detection of Near-infrared Signatures of r -process Nucleosynthesis with Gemini-South

    Energy Technology Data Exchange (ETDEWEB)

    Chornock, R. [Astrophysical Institute, Department of Physics and Astronomy, 251B Clippinger Lab, Ohio University, Athens, OH 45701 (United States); Berger, E.; Cowperthwaite, P. S.; Nicholl, M.; Villar, V. A.; Alexander, K. D.; Blanchard, P. K.; Eftekhari, T.; Williams, P. K. G. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Kasen, D. [Departments of Physics and Astronomy, and Theoretical Astrophysics Center, University of California, Berkeley, CA 94720-7300 (United States); Fong, W.; Margutti, R. [Center for Interdisciplinary Exploration and Research in Astrophysics (CIERA) and Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208 (United States); Annis, J.; Frieman, J. A. [Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510 (United States); Brout, D. [Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104 (United States); Brown, D. A. [Department of Physics, Syracuse University, Syracuse NY 13224 (United States); Chen, H.-Y. [Department of Astronomy and Astrophysics, University of Chicago, Chicago, IL 60637 (United States); Drout, M. R. [The Observatories of the Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Farr, B. [Department of Physics, University of Oregon, Eugene, OR 97403 (United States); Foley, R. J., E-mail: chornock@ohio.edu [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); and others

    2017-10-20

    We present a near-infrared spectral sequence of the electromagnetic counterpart to the binary neutron star merger GW170817 detected by Advanced Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo. Our data set comprises seven epochs of J + H spectra taken with FLAMINGOS-2 on Gemini-South between 1.5 and 10.5 days after the merger. In the initial epoch, the spectrum is dominated by a smooth blue continuum due to a high-velocity, lanthanide-poor blue kilonova component. Starting the following night, all of the subsequent spectra instead show features that are similar to those predicted in model spectra of material with a high concentration of lanthanides, including spectral peaks near 1.07 and 1.55 μ m. Our fiducial model with 0.04 M {sub ⊙} of ejecta, an ejection velocity of v = 0.1 c , and a lanthanide concentration of X {sub lan} = 10{sup −2} provides a good match to the spectra taken in the first five days, although it over-predicts the late-time fluxes. We also explore models with multiple fitting components, in each case finding that a significant abundance of lanthanide elements is necessary to match the broad spectral peaks that we observe starting at 2.5 days after the merger. These data provide direct evidence that binary neutron star mergers are significant production sites of even the heaviest r -process elements.

  6. The 'revealed preferences' theory: Assumptions and conjectures

    International Nuclear Information System (INIS)

    Green, C.H.

    1983-01-01

    Being kind of intuitive psychology the 'Revealed-Preferences'- theory based approaches towards determining the acceptable risks are a useful method for the generation of hypotheses. In view of the fact that reliability engineering develops faster than methods for the determination of reliability aims the Revealed-Preferences approach is a necessary preliminary help. Some of the assumptions on which the 'Revealed-Preferences' theory is based will be identified and analysed and afterwards compared with experimentally obtained results. (orig./DG) [de

  7. Revealing Conceptual Understanding of International Business

    Science.gov (United States)

    Ashley, Sue; Schaap, Harmen; de Bruijn, Elly

    2017-01-01

    This study aims to identify an adequate approach for revealing conceptual understanding in higher professional education. Revealing students' conceptual understanding is an important step towards developing effective curricula, assessment and aligned teaching strategies to enhance conceptual understanding in higher education. Essays and concept…

  8. REVEAL: Software Documentation and Platform Migration

    Science.gov (United States)

    Wilson, Michael A.; Veibell, Victoir T.; Freudinger, Lawrence C.

    2008-01-01

    The Research Environment for Vehicle Embedded Analysis on Linux (REVEAL) is reconfigurable data acquisition software designed for network-distributed test and measurement applications. In development since 2001, it has been successfully demonstrated in support of a number of actual missions within NASA s Suborbital Science Program. Improvements to software configuration control were needed to properly support both an ongoing transition to operational status and continued evolution of REVEAL capabilities. For this reason the project described in this report targets REVEAL software source documentation and deployment of the software on a small set of hardware platforms different from what is currently used in the baseline system implementation. This report specifically describes the actions taken over a ten week period by two undergraduate student interns and serves as a final report for that internship. The topics discussed include: the documentation of REVEAL source code; the migration of REVEAL to other platforms; and an end-to-end field test that successfully validates the efforts.

  9. A lithium-sensitive and sodium-tolerant 3'-phosphoadenosine-5'-phosphatase encoded by halA from the cyanobacterium Arthrospira platensis is closely related to its counterparts from yeasts and plants.

    Science.gov (United States)

    Zhang, Ju-Yuan; Zou, Jie; Bao, Qiyu; Chen, Wen-Li; Wang, Li; Yang, Huanming; Zhang, Cheng-Cai

    2006-01-01

    3'-Phosphoadenosine-5'-phosphatase (PAPase) is required for the removal of toxic 3'-phosphoadenosine-5'-phosphate (PAP) produced during sulfur assimilation in various eukaryotic organisms. This enzyme is a well-known target of lithium and sodium toxicity and has been used for the production of salt-resistant transgenic plants. In addition, PAPase has also been proposed as a target in the treatment of manic-depressive patients. One gene, halA, which could encode a protein closely related to the PAPases of yeasts and plants, was identified from the cyanobacterium Arthrospira (Spirulina) platensis. Phylogenic analysis indicated that proteins related to PAPases from several cyanobacteria were found in different clades, suggesting multiple origins of PAPases in cyanobacteria. The HalA polypeptide from A. platensis was overproduced in Escherichia coli and used for the characterization of its biochemical properties. HalA was dependent on Mg2+ for its activity and could use PAP or 3'-phosphoadenosine-5'-phosphosulfate as a substrate. HalA is sensitive to Li+ (50% inhibitory concentration [IC50] = 3.6 mM) but only slightly sensitive to Na+ (IC50 = 600 mM). The salt sensitivity of HalA was thus different from that of most of its eukaryotic counterparts, which are much more sensitive to both Li+ and Na+, but was comparable to the PAPase AtAHL (Hal2p-like protein) from Arabidopsis thaliana. The properties of HalA could help us to understand the structure-function relationship underlying the salt sensitivity of PAPases. The expression of halA improved the Li+ tolerance of E. coli, suggesting that the sulfur-assimilating pathway is a likely target of salt toxicity in bacteria as well.

  10. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members

    Energy Technology Data Exchange (ETDEWEB)

    Porebski, Przemyslaw J.; Klimecka, Maria; Chruszcz, Maksymilian; Nicholls, Robert A.; Murzyn, Krzysztof; Cuff, Marianne E.; Xu, Xiaohui; Cymborowski, Marcin; Murshudov, Garib N.; Savchenko, Alexei; Edwards, Aled; Minor, Wladek (MCSG); (UV); (MRC)

    2012-07-11

    Dethiobiotin synthetase (DTBS) is involved in the biosynthesis of biotin in bacteria, fungi, and plants. As humans lack this pathway, DTBS is a promising antimicrobial drug target. We determined structures of DTBS from Helicobacter pylori (hpDTBS) bound with cofactors and a substrate analog, and described its unique characteristics relative to other DTBS proteins. Comparison with bacterial DTBS orthologs revealed considerable structural differences in nucleotide recognition. The C-terminal region of DTBS proteins, which contains two nucleotide-recognition motifs, differs greatly among DTBS proteins from different species. The structure of hpDTBS revealed that this protein is unique and does not contain a C-terminal region containing one of the motifs. The single nucleotide-binding motif in hpDTBS is similar to its counterpart in GTPases; however, isothermal titration calorimetry binding studies showed that hpDTBS has a strong preference for ATP. The structural determinants of ATP specificity were assessed with X-ray crystallographic studies of hpDTBS-ATP and hpDTBS-GTP complexes. The unique mode of nucleotide recognition in hpDTBS makes this protein a good target for H. pylori-specific inhibitors of the biotin synthesis pathway.

  11. Study of high cycle fatigue of PVD surface-modified austempered ductile iron

    Energy Technology Data Exchange (ETDEWEB)

    Feng, H.P.; Lee, S.C.; Hsu, C.H.; Ho, J.M. [Tatung Inst. of Technol., Taipei (Taiwan, Province of China). Dept. of Mater. Eng.

    1999-05-25

    Austempered ductile iron (ADI) is made from ductile iron by an austempering treatment, and its main microstructure is ausferrite that is composed of acicular ferrite and high carbon austenite. The purpose of this experiment is to investigate the influence of different coating layers and the size of casting (mass effect) on the high-cycle fatigue properties of ADI. Specimens in two casting sizes of the same chemical composition were subjected to a high-toughness austempering treatment, then coated with TiN or TiCN hard films by a physical vapor deposition (PVD) process. The results showed that the fatigue limit of the small casting size ADI is 292 MPa for ADI coated with TiN and 306 MPa for ADI coated with TiCN, which are 16% and 22%, respectively, higher than that of the ADI without coating (251 MPa). For the large casting size ADI, the fatigue limits are 200, 214 and 217 MPa for ADI without coating, ADI coated with TiN and ADI coated with TiCN, respectively. ADI coated with TiN and with TiCN are 7% and 9% better than the uncoated. Thus, it is concluded that TiN and TiCN coatings by PVD can improve the high-cycle fatigue strength of ADI. This is due to the high surface hardness and possibly the ADI surface compressive residual stress as well. For the small casting size ADI, TiCN-coated specimens have a bit higher fatigue strengths and this might be attributed to the higher hardness of TiCN than TiN films. As to the effect of mass, it is found that the small casting size has better fatigue properties and benefits more from the coating films. This could have stemmed from the higher nodule count and its associated benefits in thinner castings. (orig.) 24 refs.

  12. Diamond-coated ATR prism for infrared absorption spectroscopy of surface-modified diamond nanoparticles

    Czech Academy of Sciences Publication Activity Database

    Remeš, Zdeněk; Kozak, Halyna; Rezek, Bohuslav; Ukraintsev, Egor; Babchenko, Oleg; Kromka, Alexander; Girard, H.A.; Arnault, J.-C.; Bergonzo, P.

    2013-01-01

    Roč. 270, APR (2013), s. 411-417 ISSN 0169-4332 R&D Projects: GA ČR GAP108/12/0910; GA ČR GPP205/12/P331; GA MŠk LH12236; GA MŠk LH12186 Institutional support: RVO:68378271 Keywords : ATR FTIR * CVD * hydrogenation * microwave * nanocrystalline diamond * nanopowder Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.538, year: 2013

  13. Preparation of surface modified zinc oxide nanoparticle with high capacity dye removal ability

    International Nuclear Information System (INIS)

    Mahmoodi, Niyaz Mohammad; Najafi, Farhood

    2012-01-01

    Highlights: ► Amine-functionalized zinc oxide nanoparticle (AFZON) was synthesized. ► Isotherm and kinetics data followed Langmuir isotherm and pseudo-second order kinetic model, respectively. ► Q 0 of ZON for AB25, DR23 and DR31 was 20, 12 and 15 mg/g, respectively. ► Q 0 of AFZON for AB25, DR23 and DR31 was 1250, 1000 and 1429 mg/g, respectively. ► AFZON was regenerated at pH 12. -- Abstract: In this paper, the surface modification of zinc oxide nanoparticle (ZON) by amine functionalization was studied to prepare high capacity adsorbent. Dye removal ability of amine-functionalized zinc oxide nanoparticle (AFZON) and zinc oxide nanoparticle (ZON) was also investigated. The physical characteristics of AFZON were studied using Fourier transform infrared (FTIR), scanning electron microscopy (SEM) and X-ray diffraction (XRD). Acid Blue 25 (AB25), Direct Red 23 (DR23) and Direct Red 31 (DR31) were used as model compounds. The effect of operational parameters such as dye concentration, adsorbent dosage, pH and salt on dye removal was evaluated. The isotherm and kinetic of dye adsorption were studied. The maximum dye adsorption capacity (Q 0 ) was 20 mg/g AB25, 12 mg/g DR23 and 15 mg/g DR31 for ZON and 1250 mg/g AB25, 1000 mg/g DR23 and 1429 mg/g DR31 for AFZON. It was found that dye adsorption followed Langmuir isotherm. Adsorption kinetic of dyes was found to conform to pseudo-second order kinetics. Dye desorption tests (adsorbent regeneration) showed that the maximum dye release of 90% AB25, 86% for DR23 and 90% for DR31 were achieved in aqueous solution at pH 12. Based on the data of the present investigation, it can be concluded that the AFZON being an adsorbent with high dye adsorption capacity might be a suitable alternative to remove dyes from colored aqueous solutions.

  14. Anticorrosion properties of inorganic pigments surface-modified with a polyaniline phosphate layer

    Czech Academy of Sciences Publication Activity Database

    Kalendová, A.; Veselý, D.; Stejskal, Jaroslav; Trchová, Miroslava

    2008-01-01

    Roč. 63, č. 2 (2008), s. 209-221 ISSN 0300-9440 Institutional research plan: CEZ:AV0Z40500505 Keywords : polyaniline * conducting polymer * coating Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.375, year: 2008

  15. Study of electroless copper plating on ABS resin surface modified by ...

    Indian Academy of Sciences (India)

    Many types of plas- tics can be plated, including acrylonitrile–butadiene–styrene. (ABS) resin, which is among the most widely used polymer in industry because of their excellent toughness, good dimen- sional stability, good processability, chemical resistance and low cost (Harper and Petrie 2003). In order to improve the.

  16. Surface-Modified Membrane as A Separator for Lithium-Ion Polymer Battery

    Directory of Open Access Journals (Sweden)

    Jun Young Kim

    2010-04-01

    Full Text Available This paper describes the fabrication of novel modified polyethylene (PE membranes using plasma technology to create high-performance and cost-effective separator membranes for practical applications in lithium-ion polymer batteries. The modified PE membrane via plasma modification process plays a critical role in improving wettability and electrolyte retention, interfacial adhesion between separators and electrodes, and cycle performance of lithium-ion polymer batteries. This paper suggests that the performance of lithium-ion polymer batteries can be greatly enhanced by the plasma modification of commercial separators with proper functional materials for targeted application.

  17. SURFACE-MODIFIED FERRITIC INTERCONNECT MATERIALS FOR SOLID OXIDE FUEL CELLS

    Energy Technology Data Exchange (ETDEWEB)

    Bruce R. Lanning; James Arps; Ronghua Wei; Goeff Dearnaley

    2004-03-15

    Interconnects are a critical element of an SOFC assembly and although much work has focused on chromium and chromium-iron alloys containing an oxide that is both oxidation resistant and electrically conductive, the thermal instability of typical native metal oxides allow interdiffusion of cations across the interconnect-electrode boundary that ultimately leads to degradation of SOFC performance. Phase I of the SECA Core Technology Program has been a one-year effort to investigate and evaluate the feasibility of: (1) Ion implanting an alumina-scale forming ferritic steel, such as FeCrAlY, to form an interconnect material with low resistance (< 0.1 {Omega}/cm{sup 2}) in oxidizing/reducing environments up to 800 C, and (2) Maintaining the above low resistance metric for an extended time (> 1000 hours at 800 C) in contact with an LSF cathode material. We confirmed, as part of our oxidation kinetics evaluation of FeCrAlY and 430 ferritic steel, the parabolic growth of a mixed chromia/alumina scale on FeCrAlY and a single chromia layer in the case of the 430 stainless steel; the outer contiguous layer of Al{sub 2}O{sub 3}, in the case of FeCrAlY, forming a stable, self-limiting, protective scale with no detectable cation interdiffusion between FeCrAlY and an LSF electrode even after 1000 hours at 800 C in air. To render the alumina scale conductive, we implanted either titanium or niobium ions into FeCrAlY scales to a fixed depth (0.12 {micro}m), varying only the thickness of the oxide. ASR for an un-doped FeCrAlY oxide scale (i.e., alumina) was more than an order of magnitude greater than the 430 control sample whereas, the ASR for the doped FeCrAlY oxide scale sample was comparable to the 430 control sample; hence, the resistance of a doped alumina scale on FeCrAlY was equal to the resistance of a chromia-scale forming alloy, such as 430 (chromia scales of which are typically < 0.1 {Omega}-cm). Along with the ASR measurements, AC impedance measurements were conducted to evaluate conduction mechanisms. From the AC impedance measurements, we observed that the addition of niobium resulted in at least a two order of magnitude reduction in resistance over the un-doped specimen and that the conduction in the doped alumina scale was pure electronic conduction, as opposed to mixed ionic-electronic conduction (dominated by intrinsic (ionic) defects) for the un-doped alumina scales. The DC resistance component was {approx}4 {Omega} although when this value is adjusted to account for the system resistance (i.e., leads, junctions, etc.), the ASR was determined to be < 0.1 {Omega}-cm; even after 1000 hours at 800 C in air. Our results have clearly shown that dopant additions increase the electronic conductivity of alumina forming scale alloys, such as FeCrAlY, transforming from a mixed ionic/electronic conduction mechanism. Just as importantly, the demonstrated stable formation of an alumina scale was shown to be an advantage over conventional pure chromia forming alloys as interconnect materials.

  18. Enhanced biofouling resistance of polyethersulfone membrane surface modified with capsaicin derivative and itaconic acid

    International Nuclear Information System (INIS)

    Wang, Jian; Gao, Xueli; Wang, Qun; Sun, Haijing; Wang, Xiaojuan; Gao, Congjie

    2015-01-01

    Graphical abstract: - Highlights: • PES membrane was modified with a capsaicin derivative. • UV-assisted graft polymerization was carried out on membrane surface. • The capsaicin derivative modified membrane shows better antibiofouling property. - Abstract: The culprit of biofouling is the reproduction of viable microorganisms on the membrane surface. Recently, functionalization of membrane surface with natural antibacterial agents has drawn great attention. This work presents the fabrication of antibiofouling polyethersulfone (PES) ultrafiltration (UF) membranes by UV-assisted photo grafting of capsaicin derivative (N-(4-hydroxy-3-methoxy-benzyl)-acrylamide, HMBA) and itaconic acid (IA) on the surface of PES membrane. Results of FTIR-ATR, water static contact angle (WSCA) and atomic force microscopy (AFM) analysis confirmed the successful grafting of HMBA and IA on the membrane surface. We investigated the antifouling and antibacterial properties of these membranes using BSA and Escherichia coli as the test model, respectively. During a 150-min test, the modified membranes show much lower flux decline (42.7% for PES-g-1H0I, 22.2% for PES-g-1H1I and 7.7% for PES-g-1H5I) when compared with the pristine membrane (flux declined by 77%). The modified membranes exhibit excellent antibacterial activity (nearly 100%) when UV irradiation time was 6 min. The morphological study suggested that the E. coli on the pristine membrane showed a regular and smooth surface while that on the modified membrane was disrupted, which validated the antibacterial activity of the modified membranes.

  19. Dual-surface modified virus capsids for targeted delivery of photodynamic agents to cancer cells.

    Science.gov (United States)

    Stephanopoulos, Nicholas; Tong, Gary J; Hsiao, Sonny C; Francis, Matthew B

    2010-10-26

    Bacteriophage MS2 was used to construct a targeted, multivalent photodynamic therapy vehicle for the treatment of Jurkat leukemia T cells. The self-assembling spherical virus capsid was modified on the interior surface with up to 180 porphyrins capable of generating cytotoxic singlet oxygen upon illumination. The exterior of the capsid was modified with ∼20 copies of a Jurkat-specific aptamer using an oxidative coupling reaction targeting an unnatural amino acid. The capsids were able to target and selectively kill more than 76% of the Jurkat cells after only 20 min of illumination. Capsids modified with a control DNA strand did not target Jurkat cells, and capsids modified with the aptamer were found to be specific for Jurkat cells over U266 cells (a control B cell line). The doubly modified capsids were also able to kill Jurkat cells selectively even when mixed with erythrocytes, suggesting the possibility of using our system to target blood-borne cancers or other pathogens in the blood supply.

  20. In vitro osteoinduction of human mesenchymal stem cells in biomimetic surface modified titanium alloy implants.

    Science.gov (United States)

    Santander, Sonia; Alcaine, Clara; Lyahyai, Jaber; Pérez, Maria Angeles; Rodellar, Clementina; Doblaré, Manuel; Ochoa, Ignacio

    2014-01-01

    Interaction between cells and implant surface is crucial for clinical success. This interaction and the associated surface treatment are essential for achieving a fast osseointegration process. Several studies of different topographical or chemical surface modifications have been proposed previously in literature. The Biomimetic Advanced Surface (BAS) topography is a combination of a shot blasting and anodizing procedure. Macroroughness, microporosity of titanium oxide and Calcium/Phosphate ion deposition is obtained. Human mesenchymal stem cells (hMCSs) response in vitro to this treatment has been evaluated. The results obtained show an improved adhesion capacity and a higher proliferation rate when hMSCs are cultured on treated surfaces. This biomimetic modification of the titanium surface induces the expression of osteblastic differentiation markers (RUNX2 and Osteopontin) in the absence of any externally provided differentiation factor. As a main conclusion, our biomimetic surface modification could lead to a substantial improvement in osteoinduction in titanium alloy implants.

  1. Surface characterization and stability of an epoxy resin surface modified with polyamines grafted on polydopamine

    Science.gov (United States)

    Schaubroeck, David; Vercammen, Yannick; Van Vaeck, Luc; Vanderleyden, Els; Dubruel, Peter; Vanfleteren, Jan

    2014-06-01

    This paper reports on polydopamine and polyamine surface modifications of an etched epoxy cresol novolac (ECN) resin using the 'grafting to' method. Three different polyamines are used for the grafting reactions: branched polyethyleneimine (B-PEI), linear polyethyleneimine (L-PEI) and diethylenetriamine (DETA). These modifications are compared to control materials prepared via direct deposition of polyamines. The stability of the modifications toward a concentrated hydrochloric acid (HCl) environment is evaluated. The modified surfaces are characterized with scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and time-of-flight static secondary ion mass spectroscopy (TOF-S-SIMS).

  2. The Wear behavior of UHMWPE against Surface Modified CP-Titanium by Thermal Oxidation

    Directory of Open Access Journals (Sweden)

    B.T. Prayoga

    2016-12-01

    Full Text Available The effects of thermal oxidation duration on hardness, roughness, and wettability of the CP-titanium surfaces were investigated in this paper. The thermal oxidation treatment was done at 700 oC for 12-36 hours in an air atmosphere. The wear behavior of the UHMWPE sliding against treated thermal oxidation of the CP-titanium was tested by a pin-on-plate tribometer under lubrication of the solution of 75 % distilled water and 25 % bovine serum. The results showed that the layer of the oxide titanium was formed on the surface after being treated by the thermal oxidation for 12-36 hours. The oxide titanium layer was dominated by rutile form of TiO2, that offers an improvement of hardness and wettability of the CP-titanium surfaces. The average wear factor of the UHMWPE reduced significantly when the sliding against of the CP-titanium was modified by the thermal oxidation, and the lowest average wear factor was reached when the sliding against the 12 hour oxidized CP-titanium counterfaces.

  3. Performance of Poly(lactic acid) Surface Modified Films for Food Packaging Application

    Science.gov (United States)

    Dalla Rosa, Marco; Iordanskii, Alexey L.

    2017-01-01

    Five Poly(lactic acid) (PLA) film samples were analyzed to study the gas barrier behavior, thermal stability and mechanical performance for food packaging application. O2, CO2, N2, N2O, and C2H4 pure gases; Air; and Modified Atmosphere (MA, 79% N2O/21% O2) were used to analyze the influence of the chemical structure, storage temperature and crystalline phase on the gas barrier behavior. The kinetic of the permeation process was investigated at different temperatures, ranging from 5 °C to 40 °C. Annealing thermal treatment on the samples led to the crystalline percentage, influencing especially the gas solubility process. Thermal properties such as Tg and χc, and mechanical properties such as tensile strength and modulus were remarkably improved with surface PLA modification. A more pronounced reinforcing effect was noted in the case of metallization, as well as improved gas barrier performance. Tensile testing and tensile cycling tests confirmed the rigidity of the films, with about a 20% loss of elasticity after 25 cycles loading. PMID:28773210

  4. Dispersing surface-modified imogolite nanotubes in polar and non-polar solvents

    Science.gov (United States)

    Li, Ming; Brant, Jonathan A.

    2018-02-01

    Furthering the development of nanocomposite structures, namely membranes for water treatment applications, requires that methods be developed to ensure nanoparticle dispersion in polar and non-polar solvents, as both are widely used in associated synthesis techniques. Here, we report on a two-step method to graft polyvinylpyrrolidone (PVP), and a one-step method for octadecylphosphonic acid (OPA), onto the outer surfaces of imogolite nanotubes. The goal of these approaches was to improve and maintain nanotube dispersion in polymer compatible polar and non-polar solvents. The PVP coating modified the imogolite surface charge from positive to weakly negative at pH ≤ 9; the OPA made it weakly positive at acidic pH values to negative at pH ≥ 7. The PVP surface coating stabilized the nanotubes through steric hindrance in polar protic, dipolar aprotic, and chloroform. In difference to the PVP, the OPA surface coating allowed the nanotubes to be dispersed in n-hexane and chloroform, but not in the polar solvents. The lack of miscibility in the polar solvents, as well as the better dispersion in n-hexane, was attributed to the stronger hydrophobicity of the OPA polymer relative to the PVP. [Figure not available: see fulltext.

  5. Influence of surface modified nano silica on alkyd binder before and after accelerated weathering

    DEFF Research Database (Denmark)

    Nikolic, Miroslav; Nguyen, Hiep Dinh; Daugaard, Anders Egede

    2016-01-01

    Introduction of nano fillers in exterior wood coatings is not straight forward. Influence on aging of polymer binder needs to be taken into account along with possible benefits that nano fillers can provide immediately after application. This study shows the influence of two differently modified...... polymer....

  6. Surface-Modified Quantum Dots Enhanced Luminescence Polymer Nanocomposites Light Emitting Diode

    National Research Council Canada - National Science Library

    Wei, Kung-Hwa

    2006-01-01

    .... Both the photoluminescence and electroluminescence efficiencies of the polymer nanocomposites are dramatically enhanced--sometimes by more than double--relative to the values of the pure polymer...

  7. Enhanced biofouling resistance of polyethersulfone membrane surface modified with capsaicin derivative and itaconic acid

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jian [Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao 266100 (China); College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100 (China); Gao, Xueli, E-mail: gxl_ouc@126.com [Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao 266100 (China); College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100 (China); Wang, Qun; Sun, Haijing; Wang, Xiaojuan [Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao 266100 (China); College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100 (China); Gao, Congjie, E-mail: gaocjie@ouc.edu.cn [Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao 266100 (China); College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100 (China)

    2015-11-30

    Graphical abstract: - Highlights: • PES membrane was modified with a capsaicin derivative. • UV-assisted graft polymerization was carried out on membrane surface. • The capsaicin derivative modified membrane shows better antibiofouling property. - Abstract: The culprit of biofouling is the reproduction of viable microorganisms on the membrane surface. Recently, functionalization of membrane surface with natural antibacterial agents has drawn great attention. This work presents the fabrication of antibiofouling polyethersulfone (PES) ultrafiltration (UF) membranes by UV-assisted photo grafting of capsaicin derivative (N-(4-hydroxy-3-methoxy-benzyl)-acrylamide, HMBA) and itaconic acid (IA) on the surface of PES membrane. Results of FTIR-ATR, water static contact angle (WSCA) and atomic force microscopy (AFM) analysis confirmed the successful grafting of HMBA and IA on the membrane surface. We investigated the antifouling and antibacterial properties of these membranes using BSA and Escherichia coli as the test model, respectively. During a 150-min test, the modified membranes show much lower flux decline (42.7% for PES-g-1H0I, 22.2% for PES-g-1H1I and 7.7% for PES-g-1H5I) when compared with the pristine membrane (flux declined by 77%). The modified membranes exhibit excellent antibacterial activity (nearly 100%) when UV irradiation time was 6 min. The morphological study suggested that the E. coli on the pristine membrane showed a regular and smooth surface while that on the modified membrane was disrupted, which validated the antibacterial activity of the modified membranes.

  8. Formation of biodegradable microcapsules utilizing 3D, selectively surface-modified PDMS microfluidic devices.

    Science.gov (United States)

    Liao, Chung-Yu; Su, Yu-Chuan

    2010-02-01

    We have successfully demonstrated the formation of biodegradable microcapsules utilizing PDMS double-emulsification devices. Specially designed 3D PDMS microchannels with surfaces selectively modified by a self-aligned photografting process are employed to generate monodisperse water-in-organic-solvent-in-water (W/O/W) emulsions in a controlled manner. Mainly by varying the outer and inner fluid flow-rates, the dimensions of resulting double emulsions can be adjusted as desired. Meanwhile, biodegradable materials are dissolved in the middle organic solvent (in this work ethyl acetate is used), and solidified into microcapsules once the solvent is extracted. In the prototype demonstration, microcapsules made up of poly(L-lactic acid), trilaurin, and phosphocholine were successfully fabricated. In addition, it was also demonstrated that gamma-Fe(2)O(3) nanoparticles can be simultaneously embedded into the microcapsules, which consequently become responsive to electromagnetic stimulation. As such, the presented PDMS microfluidic devices could potentially serve as versatile encapsulation apparatus, and the fabricated biodegradable microcapsules could function as controlled delivery systems, which are desired for a variety of biological and pharmaceutical applications.

  9. Surface modified Al2O3 in fluorinated polyimide/Al2O3 ...

    Indian Academy of Sciences (India)

    agglomeration. One approach to decrease the aggregation of inorganic Al2O3 is surface modification of these nanoparti- cles with coupling agent which usually has a long alkyl tail and shows a good compatibility with polymer .... ture and spatial distribution of the various components, through direct visualization. Figure 5 ...

  10. "Comparative evaluation of surface modified elastomeric ligatures for microbial colonization": An in vivo study

    Directory of Open Access Journals (Sweden)

    M Pavithra Bai

    2015-01-01

    Conclusion: Technological modifications of the elastomers using the Metafasix or OrthoShield Technology, is a definite improvement over the regular elastomers with regard to adhesion of S. mutans and Lactobacilli.

  11. Electrically controllable twisted-coiled artificial muscle actuators using surface-modified polyester fibers

    Science.gov (United States)

    Park, Jungwoo; Yoo, Ji Wang; Seo, Hee Won; Lee, Youngkwan; Suhr, Jonghwan; Moon, Hyungpil; Koo, Ja Choon; Ryeol Choi, Hyouk; Hunt, Robert; Kim, Kwang Jin; Kim, Soo Hyun; Nam, Jae-Do

    2017-03-01

    As a new class of thermally activated actuators based on polymeric fibers, we investigated polyethylene terephthalate (PET) yarns for the development of a twisted-coiled polymer fiber actuator (TCA). The PET yarn TCA exhibited the maximum linear actuation up to 8.9% by external heating at above the glass transition temperature, 160 °C-180 °C. The payload of the actuator was successfully correlated with the preload and training-load conditions by an empirical equation. Furthermore, the PET-based TCA was electrically driven by Joule heating after the PET surface was metallization with silver. For the fast and precise control of PET yarn TCA, electroless silver plating was conducted to form electrical conductive layers on the PET fiber surface. The silver plated PET-based TCA was tested by Joule heating and the tensile actuation was increased up to 12.1% (6 V) due to the enhanced surface hardness and slippage of PET fibers. Overall, silver plating of the polymeric yarn provided a fast actuation speed and enhanced actuation performance of the TCA actuator by Joule heating, providing a great potential for being used in artificial muscle for biomimetic machines including robots, industrial actuators and powered exoskeletons.

  12. Cd(II) removal on surface-modified activated carbon: equilibrium, kinetics and mechanism.

    Science.gov (United States)

    Liang, Jianjun; Liu, Meiling; Zhang, Yufei

    2016-10-01

    Commercial pulverous activated carbon (AC-0) was modified through two steps: oxidize AC-0 acid firstly, impregnate it with iron using ferric chloride secondly. Orthogonal experiment was conducted then to prepare modified activated carbon with high Cd(II) adsorption capacity (ACNF). Batch adsorption experiments were undertaken to determine the adsorption characteristics of Cd(II) from aqueous solution onto AC-0 and ACNF and the effect of pH, contact time and initial Cd(II) concentration. The results indicate that: the adsorption behavior of Cd(II) on ACNF can be well fitted with Langmuir model, and the maximum adsorption capacity of ACNF was 2.3 times higher than that of AC-0, supporting a monolayer coverage of Cd(II) on the surface. The kinetics of the adsorption process can be described by pseudo-second-order rate equation very well, and the adsorption capacity increased from 0.810 mg/g to 0.960 mg/g after modification. Compared with AC-0, the kinetic parameters of ACNF showed a higher adsorption rate through the aqueous solution to the solid surface and a lower intraparticle diffusion rate. Surface modification resulted in a lower Brunauer-Emmett-Teller (BET) surface area and pore size because of the collapse and blockage of pores, according to the X-ray diffraction (XRD) analysis, while the total number of surface oxygen acid groups increased, and this was supposed to contribute to the enhanced adsorption capacity of modified activated carbon.

  13. Plaque formation on surface modified dental implants. An in vitro study.

    Science.gov (United States)

    Grössner-Schreiber, B; Griepentrog, M; Haustein, I; Müller, W D; Lange, K P; Briedigkeit, H; Göbel, U B

    2001-12-01

    Bacterial adhesion on titanium implant surfaces has a strong influence on healing and long-term outcome of dental implants. Parameters like surface roughness and chemical composition of the implant surface were found to have a significant impact on plaque formation. The purpose of this study was to evaluate the influence of two physical hard coatings on bacterial adhesion in comparison with control surfaces of equivalent roughness. Two members of the oral microflora, Streptococcus mutans and Streptococcus sanguis were used. Commercially pure titanium discs were modified using four different surface treatments: physical vapour deposition (PVD) with either titanium nitride (TiN) or zirconium nitride (ZrN), thermal oxidation and structuring with laser radiation. Polished titanium surfaces were used as controls. Surface topography was examined by SEM and estimation of surface roughness was done using a contact stylus profilometer. Contact angle measurements were carried out to calculate surface energy. Titanium discs were incubated in the respective bacterial cell suspension for one hour and single colonies formed by adhering bacteria were counted by fluorescence microscopy. Contact angle measurements showed no significant differences between the surface modifications. The surface roughness (Ra) of all surfaces examined was between 0.14 and 1.00 microm. A significant reduction of the number of adherent bacteria was observed on inherently stable titanium hard materials such as TiN and ZrN and thermically oxidated titanium surfaces compared to polished titanium. In conclusion, physical modification of titanium implant surfaces such as coating with TiN or ZrN may reduce bacterial adherence and hence improve clinical results.

  14. Primordial germ cell differentiation of nuclear transfer embryonic stem cells using surface modified electroconductive scaffolds.

    Science.gov (United States)

    Eslami-Arshaghi, Tarlan; Vakilian, Saeid; Seyedjafari, Ehsan; Ardeshirylajimi, Abdolreza; Soleimani, Masoud; Salehi, Mohammad

    2017-04-01

    A combination of nanotopographical cues and surface modification of collagen and fibronectin is a potential platform in primordial germ cells (PGCs) differentiation. In the present study, the synergistic effect of nanotopography and surface modification on differentiation of nuclear transfer embryonic stem cells (nt-ESCs) toward PGC lineage was investigated. In order to achieve this goal, poly-anyline (PANi) was mix within poly-L-lactic acid (PLLA). Afterward, the random composite mats were fabricated using PLLA and PANi mix solution. The nanofiber topography notably upregulated the expressions of prdm14, mvh and c-kit compared with tissue culture polystyrene (TCP). Moreover, the combination of nanofiber topography and surface modification resulted in more enhancement of PGCs differentiation compared with non-modified nanofibrous scaffold. Additionally, gene expression results showed that mvh and c-kit were expressed at higher intensity in cells exposed to collagen and fibronectin rather than collagen or fibronectin solitary. These results demonstrated the importance of combined effect of collagen and fibronectin in order to develop a functional extracellular matrix (ECM) mimic in directing stem cell fate and the potential of such biofunctional scaffolds for treatment of infertility.

  15. Study of electroless copper plating on ABS resin surface modified by ...

    Indian Academy of Sciences (India)

    Metallization of plastics is widely used today in various tech- nological fields from the fabrication of printed circuits in ... Palladium chloride and stannous chloride crystals were stored in a vacuum dessicator prior to use. .... ABS resin surface after the metallization process, according to the following equations, respectively a =.

  16. PERFORMANCE OF CEMENT COMPOSITES REINFORCED WITH SURFACE-MODIFIED POLYPROPYLENE MICRO- AND MACRO-FIBERS

    Directory of Open Access Journals (Sweden)

    Jakub Antoš

    2017-11-01

    Full Text Available This paper focuses on the mechanical properties investigation of cement pastes reinforced with surface treated polymer fibers. The cement matrix was composed of Portland cement (CEM I 42.5 R, w/c ratio equal to 0.4. Two polypropylene fiber types (micro- and macro-fibers were used as randomly distributed and oriented reinforcement in volume amount of 2 %. The fibers were modified in the low-pressure inductively coupled cold oxygen plasma in order to enhance their surface interaction with the cement matrix. The investigated composite mechanical properties (load bearing capacity and response during loading were examined indirectly by means of four-point bending mechanical destructive tests. A response of loaded samples containing treated fibers were compared to samples with reference fibers. Moreover, cracking behavior development was monitored using digital image correlation (DIC. This method enabled to record the micro-cracks system evaluation of both fiber reinforced samples.

  17. Polysiloxane surface modified with bipyrazolic tripodal receptor for quantitative lead adsorption

    Energy Technology Data Exchange (ETDEWEB)

    Radi, Smaail, E-mail: radi_smaail@yahoo.fr [Laboratoire de Chimie Organique, Macromoleculaire et Produits Naturels, Equipe de Chimie Bio-organique et Macromoleculaire, Unite Associee au CNRST URAC 25, Departement de Chimie, Faculte des Sciences, Universite Med I, BP 524, 60 000 Oujda (Morocco); Tighadouini, Said; Toubi, Yahya [Laboratoire de Chimie Organique, Macromoleculaire et Produits Naturels, Equipe de Chimie Bio-organique et Macromoleculaire, Unite Associee au CNRST URAC 25, Departement de Chimie, Faculte des Sciences, Universite Med I, BP 524, 60 000 Oujda (Morocco); Bacquet, Maryse [Universite des Sciences et Technologies de Lille, UMET: Unite Materiaux et Transformations UMR8207, Equipe Ingenierie des Systemes Polymeres, Batiment C6 salle 119-59655 Villeneuve d' Ascq (France)

    2011-01-15

    A new silica gel compound modified N,N-bis(3,5-dimethylpyrazol-1-ylmethyl) amine (SiN{sub 2}Pz) was synthesized and characterized by elemental analysis, FT-IR, {sup 13}C NMR of the solid state, nitrogen adsorption-desorption isotherm, BET surface area and BJH pore sizes. The new surface exhibits good chemical and thermal stability determined by thermogravimetry curves (TGA). The effect of pH and stirring time on the adsorption of Pb(II) were studied. The process of metal retention was followed by batch method and the optimum pH value for the quantitative adsorption of this toxic metal ion was 7. At this pH value, the new functionalized polysiloxane presents further improvements and shows higher affinity (123 mg of Pb{sup 2+}/g of silica) for the effective adsorption of Pb(II) compared to others described sorbents. The extracted amounts of Pb(II) were determined by atomic absorption measurements.

  18. Electrocatalytic behaviour and application of manganese porphyrin/gold nanoparticle- surface modified glassy carbon electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Sebarchievici, I., E-mail: incemc@incemc.ro [National Institute of Research for Electrochemistry and Condensed Matter, Aurel Paunescu Podeanu Street 144, 300569 Timisoara (Romania); Tăranu, B.O. [National Institute of Research for Electrochemistry and Condensed Matter, Aurel Paunescu Podeanu Street 144, 300569 Timisoara (Romania); Birdeanu, M. [National Institute of Research for Electrochemistry and Condensed Matter, Aurel Paunescu Podeanu Street 144, 300569 Timisoara (Romania); Institute of Chemistry Timisoara of Romanian Academy, M. Viteazul Ave. 24, 300223 Timisoara (Romania); Rus, S.F. [National Institute of Research for Electrochemistry and Condensed Matter, Aurel Paunescu Podeanu Street 144, 300569 Timisoara (Romania); Fagadar-Cosma, E., E-mail: efagadar@yahoo.com [Institute of Chemistry Timisoara of Romanian Academy, M. Viteazul Ave. 24, 300223 Timisoara (Romania)

    2016-12-30

    Highlights: • Mn-porphyrin/gold nanoparticle-modified glassy carbon electrodes were obtained. • AFM investigations of thin films display multilayer of triangular type architecture. • Oxidation and reduction processes of H{sub 2}O{sub 2} are diffusion controled. • There is a linear dependence between H{sub 2}O{sub 2} concentration and the currents intensity. • The modified electrodes show better electrochemical detection ability to H{sub 2}O{sub 2}. - Abstract: The main purpose of this research was to obtain manganese porphyrin/gold nanoparticle-modified glassy carbon electrodes and to use them for the detection of H{sub 2}O{sub 2}. Two sets of modified electrodes were prepared by drop-cast deposition of 5,10,15,20-tetra(4-methyl-phenyl)porphyrinato manganese(III) chloride alone and of the same Mn-porphyrin and gold-colloid solution and comparatively characterized by Raman, UV–vis, ellipsometry, AFM and TEM microscopy, XPS and cyclic voltammetry. XPS spectrum recorded for GC-MnP-nAu modified electrode displayed the characteristic signals of gold nanoparticles. The optical parameters have greater values for GC-MnP-nAu in comparison with GC-MnP, due to increasing charge transfer efficiency. The MnP-nAu film mediates the electron transfer between H{sub 2}O{sub 2} and GC, evidenced by an increase in the current intensity of the anodic peak, and facilitates the electrochemical regeneration of oxidized H{sub 2}O{sub 2} at cathodic potentials. From the cyclic voltammetry experiments a linear relationship between H{sub 2}O{sub 2} concentration vs oxidation and reduction currents was observed. The linear dependence between density of current and the square root of the scan rate indicates that the oxidation and reduction processes of H{sub 2}O{sub 2} are diffusion controlled. The GC-MnP-nAu modified electrode shows great potential as electrochemical sensor for determination of hydrogen peroxide.

  19. Electronic Structure of Hydrogenated and Surface-Modified GaAs Nanocrystals: Ab Initio Calculations

    Directory of Open Access Journals (Sweden)

    Hamsa Naji Nasir

    2012-01-01

    Full Text Available Two methods are used to simulate electronic structure of gallium arsenide nanocrystals. The cluster full geometrical optimization procedure which is suitable for small nanocrystals and large unit cell that simulates specific parts of larger nanocrystals preferably core part as in the present work. Because of symmetry consideration, large unit cells can reach sizes that are beyond the capabilities of first method. The two methods use ab initio Hartree-Fock and density functional theory, respectively. The results show that both energy gap and lattice constant decrease in their value as the nanocrystals grow in size. The inclusion of surface part in the first method makes valence band width wider than in large unit cell method that simulates the core part only. This is attributed to the broken symmetry and surface passivating atoms that split surface degenerate states and adds new levels inside and around the valence band. Bond length and tetrahedral angle result from full geometrical optimization indicate good convergence to the ideal zincblende structure at the centre of hydrogenated nanocrystal. This convergence supports large unit cell methodology. Existence of oxygen atoms at nanocrystal surface melts down density of states and reduces energy gap.

  20. Immunosensing by luminescence reduction in surface-modified microstructured SU-8

    Energy Technology Data Exchange (ETDEWEB)

    Eravuchira, Pinkie Jacob; Baranowska, Malgorzata; Eckstein, Chris [Departament d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avda. Països Catalans 26, Tarragona 43007 (Spain); Díaz, Francesc [Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, Marcelí Domingo s/n, Tarragona 43007 (Spain); Llobet, Eduard; Marsal, Lluis F. [Departament d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avda. Països Catalans 26, Tarragona 43007 (Spain); Ferré-Borrull, Josep, E-mail: josep.ferre@urv.cat [Departament d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avda. Països Catalans 26, Tarragona 43007 (Spain)

    2017-01-15

    Highlights: • The reduction of photoluminescence of SU-8 upon surface modification is reported. • Micropillar structuring of SU-8 surface results in an increased photoluminescence reduction rate (10% glass, 15% silicon). • Photoluminescence reduction rate can be a transduction parameter for the detection of antibody-antigen binding events. • The proposed sensing mechanism can be used to quantify small concentrations of antibody. • Lower limit of detection (LOD) of 28 μg/ml on silicon substrates and 42 μg/ml on glass substrates was achieved. - Abstract: SU-8, an epoxy based negative photoresist is extensively used as a structural material for the fabrication of microelectro-mechanical systems and in microelectronics technology. However, the possible applications of SU-8 for biosensing have not been explored much, mainly because of the photoluminescence SU-8 possesses in the near-UV and visible wavelength ranges which hinders fluorescent labelling of biorecognition events. In this study we demonstrate that photoluminescence of SU-8 can be employed itself as a sensing transduction parameter to produce a tool for immunosensing: the photoluminescence shows a systematic reduction upon modification of its surface chemistry, and in particular upon attachment of an antigen-antibody (aIgG-IgG) pair. We investigate the relation of the amount of reduction of photoluminescence on planar and microstructured surfaces, and we show that microstructuring leads to a higher reduction than a planar surface. Furthermore, we evaluated the dependence of photoluminescence reduction as a function of analyte concentration to prove that this magnitude can be applied to immunosensing.

  1. Surface-Modified Electrodes: Enhancing Performance Guided by Insitu Spectroscopy and Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Chueh, William [Stanford Univ., CA (United States)

    2016-12-01

    The aim of this project is to understand the nature of active sites and degradation mechanisms in solid-oxide fuel cells cathodes. Using Co and Fe-based perovskite oxides as model systems, we developed a comprehensive understanding of the active site and degradation. In particular, we correlated cation segregation, precipitation and surface reconstruction to electrochemical activity and stability. We show that in conventional materials, the most active cathodes are not the most stable ones. A novel strategy of cation segregation buffer layer was proposed and developed to overcome this limitation. A nanoscale barrier layer was inserted a few nanometer below the surface of the cathodes which prevents the cations from diffusing from the bulk to the surface. We report a LSCF-based cathode with record performance and stability, reach an impressive 0.03 Ω cm2 at 650 °C in air. This modification strategy is expected to lead to more active and stable solid-oxide fuel cells, and ultimately lead to lower cost in commercial systems.

  2. Electrochemical immobilization of biomolecules on gold surface modified with monolayered L-cysteine

    International Nuclear Information System (INIS)

    Honda, Mitsunori; Baba, Yuji; Sekiguchi, Tetsuhiro; Shimoyama, Iwao; Hirao, Norie

    2014-01-01

    Immobilization of organic molecules on the top of a metal surface is not easy because of lattice mismatch between organic and metal crystals. Gold atoms bind to thiol groups through strong chemical bonds, and a self-assembled monolayer of sulfur-terminated organic molecules is formed on the gold surface. Herein, we suggested that a monolayer of L-cysteine deposited on a gold surface can act as a buffer layer to immobilize biomolecules on the metal surface. We selected lactic acid as the immobilized biomolecule because it is one of the simplest carboxyl-containing biomolecules. The immobilization of lactic acid on the metal surface was carried out by an electrochemical method in an aqueous environment under the potential range varying from − 0.6 to + 0.8 V. The surface chemical states before and after the electrochemical reaction were characterized using X-ray photoelectron spectroscopy (XPS). The N 1s and C 1s XPS spectra showed that the L-cysteine-modified gold surface can immobilize lactic acid via peptide bonds. This technique might enable the immobilization of large organic molecules and biomolecules. - Highlights: • Monolayer l-cysteine deposited on Au surface as a buffer layer to immobilize biomolecules. • Lactic acid as the immobilized biomolecule as it is simple carboxyl-containing biomolecule. • X-ray photoelectron spectroscopy (XPS) of surface chemical states, before and after. • L-cysteine-modified Au surface can immobilize lactic acid via peptide bonds

  3. The biomedical properties of polyethylene terephthalate surface modified by silver ion implantation

    International Nuclear Information System (INIS)

    Wang Jin; Li Jianxin; Shen Liru; Ling Ren; Xu Zejin; Zhao Ansha; Leng Yongxiang; Huang Nan

    2007-01-01

    Polyethylene terephthalate (PET) film is modified by Ag ion implantation with a fluence 1 x 10 16 ions/cm 2 . The results of X-Ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) indicate that silver has been successfully implanted into the surface of PET. The PET samples modified by silver ion implantation have significantly bactericidal property. The capacity of the staphylococcus epidermidis (SE) adhered on the Ag + implanted PET surface is 5.3 x 10 6 CFU/ml, but the capacity of the SE adhered on the untreated PET film is 2.23 x 10 7 CFU/ml. The thromboembolic property is evaluated by in vitro platelet adhesion test, and there is not statistically difference between the untreated PET and the Ag + implanted PET for the number of adhered and activated platelets. The PET implanted by silver ion has not acute toxicity to endothelial cell (EC) which was evaluated by the release of lactate dehydrogenase (LDH) test

  4. Removal of Uranium from Radioactive Liquid Waste by Surface-modified Bio sorbents

    International Nuclear Information System (INIS)

    Lee, Keunyoung; Baek, Yeji; Kim, Kwangwook; Lee, Eilhee; Chung, Dongyong; Moon, Jeikwon

    2013-01-01

    Recently, bio sorption technology using microorganisms, plants, and other various bio masses has been considered as an alternative to the metal adsorption process by chemical adsorbents. In this study, the feasibility test of bio sorption for uranium removal from liquid waste was performed, and the removal properties of uranium by pretreated brown algae were evaluated in various experimental conditions. The radioactive liquid waste containing uranium mainly generated during the operation of nuclear power plants or related facilities such as nuclear research laboratories and nuclear fuel manufacturing plants. Due to its radioactivity and high toxicity, uranium is one of the most seriously hazardous materials for the environment and finally human body. Therefore the development of treatment technology for the uranium-containing liquid waste has been required

  5. Colloidally stable surface-modified iron oxide nanoparticles: preparation, characterization and anti-tumor activity

    Czech Academy of Sciences Publication Activity Database

    Macková, Hana; Horák, Daniel; Donchenko, G. V.; Andriyaka, V. I.; Palyvoda, O. M.; Chernishov, V. I.; Chekhun, V. F.; Todor, I. N.; Kuzmenko, O. I.

    2015-01-01

    Roč. 380, 15 April (2015), s. 125-131 ISSN 0304-8853. [International Conference on the Scientific and Clinical Applications of Magnetic Carriers /10./. Dresden, 10.06.2014-14.06.2014] R&D Projects: GA MŠk 7E12054; GA MŠk(CZ) LH14318; GA MŠk(CZ) ED1.1.00/02.0109 EU Projects: European Commission(XE) 259796 - DIATOOLS Institutional support: RVO:61389013 Keywords : iron oxide nanoparticle * poly(N,N-dimethylacrylamide-co-acrylic acid) * protein oxidation Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.357, year: 2015

  6. On-chip surface modified nanostructured ZnO as functional pH sensors

    Science.gov (United States)

    Zhang, Qing; Liu, Wenpeng; Sun, Chongling; Zhang, Hao; Pang, Wei; Zhang, Daihua; Duan, Xuexin

    2015-09-01

    Zinc oxide (ZnO) nanostructures are promising candidates as electronic components for biological and chemical applications. In this study, ZnO ultra-fine nanowire (NW) and nanoflake (NF) hybrid structures have been prepared by Au-assisted chemical vapor deposition (CVD) under ambient pressure. Their surface morphology, lattice structures, and crystal orientation were investigated by scanning electron microscopy (SEM), x-ray diffraction (XRD), and transmission electron microscopy (TEM). Two types of ZnO nanostructures were successfully integrated as gate electrodes in extended-gate field-effect transistors (EGFETs). Due to the amphoteric properties of ZnO, such devices function as pH sensors. We found that the ultra-fine NWs, which were more than 50 μm in length and less than 100 nm in diameter, performed better in the pH sensing process than NW-NF hybrid structures because of their higher surface-to-volume ratio, considering the Nernst equation and the Gouy-Chapman-Stern model. Furthermore, the surface coating of (3-Aminopropyl)triethoxysilane (APTES) protects ZnO nanostructures in both acidic and alkaline environments, thus enhancing the device stability and extending its pH sensing dynamic range.

  7. Smart polymers as surface modifiers for bioanalytical devices and biomaterials: theory and practice

    Science.gov (United States)

    Ivanov, A. E.; Zubov, V. P.

    2016-06-01

    Smart, or responsive polymers can reversibly change their state of aggregation, thus switching from water-soluble to insoluble state, in response to minor changes in temperature, pH or solvent composition. Grafting of these polymers to solid surfaces imparts the surfaces with controllable wettability and adsorption behaviour. The review summarizes the theoretical models and the results of physical measurements of the conformational transitions in grafted polymer chains and polymer brushes. Primary attention is paid to the grafting density and the length and spatial arrangement of grafted chains, the role of polystyrene, organosilane or alkanethiol sublayers and their effects on adsorption of proteins and adhesion of cells. The key applications of grafted smart polymers such as cell culture and tissue engineering, cell and protein separation, biosensing and targeted drug delivery are surveyed. The bibliography includes 174 references.

  8. Adhesion, growth and differentiation of osteoblasts on surface-modified materials developed for bone implants

    Czech Academy of Sciences Publication Activity Database

    Vandrovcová, Marta; Bačáková, Lucie

    2011-01-01

    Roč. 60, č. 3 (2011), s. 403-417 ISSN 0862-8408 R&D Projects: GA AV ČR(CZ) KAN101120701; GA AV ČR(CZ) KAN400480701; GA ČR(CZ) GAP108/10/1858; GA ČR(CZ) GA106/09/1000 Institutional research plan: CEZ:AV0Z50110509 Keywords : osteogenic cells * bone tissue engineering Subject RIV: EI - Biotechnology ; Bionics Impact factor: 1.555, year: 2011

  9. XPS analysis of the carbon fibers surface modified via HMDSO to carbon nanotube growth

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, L.D.R.; Gomes, M.C.B.; Trava-Airoldi, V.J.; Corat, E.J.; Lugo, D.C. [Instituto Nacional de Pesquisas Espaciais (INPE), Sao Jose dos Campos, SP (Brazil)

    2016-07-01

    Full text: Carbon fibers (CF) have been widely used to reinforce structural composites. Due to their strength-to-weight properties, CF composites are finding increased structural uses in areas such as aerospace, aeronautical, automobile and others. The strength of the fiber-resin interface bond has been found to be the limiting factor to the mechanical properties of CF-epoxy materials, due to their non-polar nature that limit the affinity of CF to bind chemically to any matrix. The growth of carbon nanotubes (CNTs) on the surface of CF is a promising approach for improving mechanical, electrical and thermal properties of structural composites. However growing CNTs on CF presents some obstacles, such as diffusion of metal catalyst particles on CF, uneven CNT growth and loss of mechanical properties of CF. To avoid the diffusion of catalyst particles we modified the CF surface with hexamethyldisiloxane (HMDSO) at low temperature (400 °C), also preventing the loss of mechanical properties and allowing uniform CNTs growth. We deposited CNTs via floating catalyst method, with ferrocene providing the catalyst particle and the oxidative dehydrogenation reaction of acetylene providing the carbon. The CF surface modification was analyzed via X-ray photoelectron spectroscopy (XPS) and CNTs growth via scanning electron microscopy with field emission gun. The XPS analysis showed that HMDSO promotes the binding of oxygen to carbon and silicon present on CF surface, the chemical modification of the surface of the CF enables the uniform growth of carbon nanotubes. (author)

  10. XPS analysis of the carbon fibers surface modified via HMDSO to carbon nanotube growth

    International Nuclear Information System (INIS)

    Cardoso, L.D.R.; Gomes, M.C.B.; Trava-Airoldi, V.J.; Corat, E.J.; Lugo, D.C.

    2016-01-01

    Full text: Carbon fibers (CF) have been widely used to reinforce structural composites. Due to their strength-to-weight properties, CF composites are finding increased structural uses in areas such as aerospace, aeronautical, automobile and others. The strength of the fiber-resin interface bond has been found to be the limiting factor to the mechanical properties of CF-epoxy materials, due to their non-polar nature that limit the affinity of CF to bind chemically to any matrix. The growth of carbon nanotubes (CNTs) on the surface of CF is a promising approach for improving mechanical, electrical and thermal properties of structural composites. However growing CNTs on CF presents some obstacles, such as diffusion of metal catalyst particles on CF, uneven CNT growth and loss of mechanical properties of CF. To avoid the diffusion of catalyst particles we modified the CF surface with hexamethyldisiloxane (HMDSO) at low temperature (400 °C), also preventing the loss of mechanical properties and allowing uniform CNTs growth. We deposited CNTs via floating catalyst method, with ferrocene providing the catalyst particle and the oxidative dehydrogenation reaction of acetylene providing the carbon. The CF surface modification was analyzed via X-ray photoelectron spectroscopy (XPS) and CNTs growth via scanning electron microscopy with field emission gun. The XPS analysis showed that HMDSO promotes the binding of oxygen to carbon and silicon present on CF surface, the chemical modification of the surface of the CF enables the uniform growth of carbon nanotubes. (author)

  11. Structural, electronic and mechanical properties of inner surface modified imogolite nanotubes

    Directory of Open Access Journals (Sweden)

    Maurício Chagas Da Silva

    2015-03-01

    Full Text Available The electronic, structural and mechanical properties of the modified imogolites have been investigated using self consistent charge-density functional-tight binding method with a posteriori treatment of the dispersion interaction (SCC-DFTB-D. The zigzag (12,0 imogolite has been used as the initial structure for the calculations. The functionalization of the interior (12,0 imogolite nanotubes by organosilanes and by heat treatment leading to the dehydroxylation of the silanols were investigated. The reaction of the silanols with the trimethylmethoxysilanes is favored and the arrangement of the different substitutions that leads to the most symmetrical structures are preferred. The Young moduli and band gaps are slightly decreased. However, the dehydroxylation of the silanol groups in the inner surface of the imogolite leads to the increase of the Young moduli and a drastic decrease of the band gap of about 4.4 eV. It has been shown that the degree of the dehydroxylation can be controlled by heat treatment and tune the band gap, eventually, leading to a semiconductor material with well defined nanotube structure.

  12. Entropic solvation force between surfaces modified by grafted chains: a density functional approach

    Directory of Open Access Journals (Sweden)

    O. Pizio

    2010-01-01

    Full Text Available The behavior of a hard sphere fluid in slit-like pores with walls modified by grafted chain molecules composed of hard sphere segments is studied using density functional theory. The chains are grafted to opposite walls via terminating segments forming pillars. The effects of confinement and of "chemical" modification of pore walls on the entropic solvation force are investigated in detail. We observe that in the absence of adsorbed fluid the solvation force is strongly repulsive for narrow pores and attractive for wide pores. In the presence of adsorbed fluid both parts of the curve of the solvation force may develop oscillatory behavior dependent on the density of pillars, the number of segments and adsorption conditions. Also, the size ratio between adsorbed fluid species and chain segments is of importance for the development of oscillations. The choice of these parameters is crucial for efficient manipulation of the solvation force as desired for pores of different width.

  13. Interaction between Palladium Nanoparticles and Surface-Modified Carbon Nanotubes: Role of Surface Functionalities

    DEFF Research Database (Denmark)

    Zhang, Bingsen; Shao, Lidong; Zhang, Wei

    2014-01-01

    degrees C. We focus on probing the effects of oxygen and nitrogen-containing functional groups on supported palladium nanoparticles (NPs) in the model catalytic system. The stability of palladium NPs supported on CNTs depends strongly on the surface properties of CNTs. Moreover, the oxygen...... feature, instability, and subtle response of the components upon application of an external field. Herein, we use insitu TEM, electron energy loss spectroscopy, and X-ray photoelectron spectroscopy techniques to record the interaction in palladium on carbon nanotubes (CNTs) from room temperature to 600...

  14. Synthesis and characterization of surface-modified Fe3O4 super-paramagnetic nanoparticles.

    Science.gov (United States)

    Zhang, Zhan-jie; Ma, Jia; Xu, Shuang-bing; Ren, Jing-hua; Qin, You; Huang, Jing; Yang, Kun-yu; Zhang, Zhi-ping; Wu, Gang

    2014-04-01

    Aqueous dispersion and stability of Fe3O4 nanoparticles remain an issue unresolved since aggregation of naked iron nanoparticles in water. In this study, we successfully synthesized different Fe3O4 super-paramagnetic nanoparticles which were modified by three kinds of materials [DSPE-MPEG2000, TiO2 and poly acrylic acid (PAA)] and further detected their characteristics. Transmission electron microscopy (TEM) clearly showed sizes and morphology of the four kinds of nanoparticles. X-ray diffraction (XRD) proved successfully coating of the three kinds of nanoparticles and their structures were maintained. Vibrating sample magnetometer (VSM) verified that their magnetic properties fitted for the super-paramagnetic function. More importantly, the particle size analysis indicated that Fe3O4@PAA had a better size distribution, biocompatibility, stability and dispersion than the other two kinds of nanoparticles. In addition, using CNE2 cells as a model, we found that all nanoparticles were nontoxic. Taken together, our data suggest that Fe3O4@PAA nanoaparticles are superior in the application of biomedical field among the four kinds of Fe3O4 nanoparticles in the future.

  15. Bone Formation from Porcine Dental Germ Stem Cells on Surface Modified Polybutylene Succinate Scaffolds

    Directory of Open Access Journals (Sweden)

    Nergis Abay

    2016-01-01

    Full Text Available Designing and providing a scaffold are very important for the cells in tissue engineering. Polybutylene succinate (PBS has high potential as a scaffold for bone regeneration due to its capacity in cell proliferation and differentiation. Also, stem cells from 3rd molar tooth germs were favoured in this study due to their developmentally and replicatively immature nature. In this study, porcine dental germ stem cells (pDGSCs seeded PBS scaffolds were used to investigate the effects of surface modification with fibronectin or laminin on these scaffolds to improve cell attachment, proliferation, and osteogenic differentiation for tissue engineering applications. The osteogenic potentials of pDGSCs on these modified and unmodified foams were examined to heal bone defects and the effects of fibronectin or laminin modified PBS scaffolds on pDGSC differentiation into bone were compared for the first time. For this study, MTS assay was used to assess the cytotoxic effects of modified and unmodified surfaces. For the characterization of pDGSCs, flow cytometry analysis was carried out. Besides, alkaline phosphatase (ALP assay, von Kossa staining, real-time PCR, CM-Dil, and immunostaining were applied to analyze osteogenic potentials of pDGSCs. The results of these studies demonstrated that pDGSCs were differentiated into osteogenic cells on fibronectin modified PBS foams better than those on unmodified and laminin modified PBS foams.

  16. Characterization of a surface modified carbon cryogel and a carbon supported Pt catalyst

    Directory of Open Access Journals (Sweden)

    BILJANA M. BABIĆ

    2007-08-01

    Full Text Available A carbon cryogel, synthesized by carbonization of a resorcinol/formaldehyde cryogel and oxidized in nitric acid, was used as catalyst support for Pt nano-particles. The Pt/C catalyst was prepared by a modified polyol synthesis method in an ethylene glycol (EG solution. Characterization by nitrogen adsorption showed that the carbon cryogel support and the Pt/C catalyst were mesoporous materials with high specific surface areas (SBET > 400 m2 g-1 and large mesoporous volumes. X-Ray diffraction of the catalyst demonstrated the successful reduction of the Pt precursor to metallic form. TEM Images of the Pt/C catalyst and Pt particle size distribution showed that the mean Pt particle size was about 3.3 nm. Cyclic voltammetry (CV experiments at various scan rates (from 2 to 200 mV s-1 were performed in 0.5 mol dm-3 HClO4 solution. The large capacitance of the oxidized carbon cryogel electrode, which arises from a combination of the double-layer capacitance and pseudocapacitance, associated with the participation of surface redox-type reactions was demonstrated. For the oxidized carbon cryogel, the total specific capacitance determined by 1/C vs. ν0.5 extrapolation method was found to be 386 F g-1. The hydrogen oxidation reaction at the investigated Pt/C catalyst proceeded as an electrochemically reversible, two-electron direct discharge reaction.

  17. Molybdenum and tungsten disulfides surface-modified with a conducting polymer, polyaniline, for application in electrorheology

    Czech Academy of Sciences Publication Activity Database

    Stejskal, Jaroslav; Mrlík, M.; Plachý, T.; Trchová, Miroslava; Kovářová, Jana; Li, Yu

    2017-01-01

    Roč. 120, November (2017), s. 30-37 ISSN 1381-5148 R&D Projects: GA ČR(CZ) GA17-04109S Institutional support: RVO:61389013 Keywords : molybdenum sulfide * polyaniline * conducting polymer Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 3.151, year: 2016

  18. Antibacterial surface modified of novel nanocomposite sulfonated polyethersulfone/polyrhodanine membrane

    Science.gov (United States)

    Rostam, Abbas Babaei; Peyravi, Majid; Ghorbani, Mohsen; Jahanshahi, Mohsen

    2018-01-01

    In this study, sulfonated-polyethersulfone/polyrhodanine (SPES/PRh) membranes with antibacterial behavior were fabricated. Polyethersulfone (PES) sulfonation was performed to enhance its hydrophilicity and next polyrhodanine nanoparticles (PRhNPs) were synthesized along with the sulfonated PES (SPES) by polyrhodanine (PRh) in situ polymerization. The sulfonation step also helps making composite membrane due to development of probable bondings and polymers engagements. The constructed membranes characterization was performed by FTIR, FESEM, contact angle, 1H NMR, TGA and EDS analyses. SPES/PRh membrane had enhanced hydrophilicity and consequently better fluxes for aqueous solutions. The composite SPES/PRh membrane flux was improved to 139/78 L/m2 h comparing 58.21 L/m2 h for SPES one. Membrane operational performances, antibacterial and antibiofouling tests showed improved flux, better rejection and appropriate antibacterial and antibiofouling properties for SPES/PRh membrane. The 100% bacteria mortality for specified concentrations and appropriate inhibition zones up to 9 mm have been achieved. It is generally a suitable membrane to provide proper performance beside antibacterial and antibiofouling behavior.

  19. Micro-orientation control of silicon polymer thin films on graphite surfaces modified by heteroatom doping

    Energy Technology Data Exchange (ETDEWEB)

    Shimoyama, Iwao, E-mail: shimoyama.iwao@jaea.go.jp [Material Science Research Center, Atomic Energy Agency, Tokai-mura 2-4, Naka-gun, Ibaraki 319-1195 (Japan); Baba, Yuji [Fukushima Administrative Department, Atomic Energy Agency, Tokai-mura 2-4, Naka-gun, Ibaraki 319-1195 (Japan); Hirao, Norie [Material Science Research Center, Atomic Energy Agency, Tokai-mura 2-4, Naka-gun, Ibaraki 319-1195 (Japan)

    2017-05-31

    Highlights: • Micro-orientation control method for organic polysilane thin films is proposed. • This method utilizes surface modification of graphite using heteroatom doping. • Lying, standing, and random orientations can be freely controlled by this method. • Micro-pattering of a polysilane film with controlled orientations is achieved. - Abstract: Near-edge X-ray absorption fine structure (NEXAFS) spectroscopy is applied to study orientation structures of polydimethylsilane (PDMS) films deposited on heteroatom-doped graphite substrates prepared by ion beam doping. The Si K-edge NEXAFS spectra of PDMS show opposite trends of polarization dependence for non irradiated and N{sub 2}{sup +}-irradiated substrates, and show no polarization dependence for an Ar{sup +}-irradiated substrate. Based on a theoretical interpretation of the NEXAFS spectra via first-principles calculations, we clarify that PDMS films have lying, standing, and random orientations on the non irradiated, N{sub 2}{sup +}-irradiated, and Ar{sup +}-irradiated substrates, respectively. Furthermore, photoemission electron microscopy indicates that the orientation of a PDMS film can be controlled with microstructures on the order of μm by separating irradiated and non irradiated areas on the graphite surface. These results suggest that surface modification of graphite using ion beam doping is useful for micro-orientation control of organic thin films.

  20. Biological evaluation of surface-modified magnetic nanoparticles as a platform for colon cancer cell theranostics

    Czech Academy of Sciences Publication Activity Database

    Moskvin, Maksym; Babič, Michal; Reis, S.; Cruz, M. M.; Ferreira, L. P.; Deus Carvalho, M.; Costa Lima, S. A.; Horák, Daniel

    2018-01-01

    Roč. 161, 1 January (2018), s. 35-41 ISSN 0927-7765 R&D Projects: GA ČR(CZ) GC16-01128J EU Projects: European Commission(XE) COST Action TD1402 Institutional support: RVO:61389013 Keywords : iron oxide nanoparticles * carbohydrates * poly(N,N-dimethylacrylamide) Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 3.887, year: 2016

  1. Optical properties study of silicone polymer PDMS substrate surfaces modified by plasma treatment

    Science.gov (United States)

    Zahid, A.; Dai, B.; Hong, R.; Zhang, D.

    2017-10-01

    In this study, PDMS (polydimethylsiloxane) substrates with a half-plain, half-rough surface were prepared on a plain and rough fused silica glass substrate using a molding technique. The molded PDMS surface morphology was changed into a half-smooth and half-rough surface after peeling. The modified PDMS surfaces’ optical properties were inspected with and without treatment. The treatment is exposed by oxygen plasma (15 W) for 3 min in a vacuum, down to a pressure of six torr, using a vacuum pump. An atomic force microscope (AMF) and interferometer (white light) indicated that the plasma O2 treatment increased the formation of the plain surface and decreased the formation of the rough surface. The optical properties via a spectrophotometer (lambda) show the resonance from 300 nm to 1200 nm on the rough surface, which is considered to be a faithful reproduction for transmittance and reflectance. The Raman spectra and FDTD simulation results are in excellent agreement; not to be confused with metal local surface plasmon resonances (LSPRs). The Raman spectra peaks and hotspot are the results of the PDMS Si-O backbone. The PDMS substrate presented the diversity of the optical properties, which makes the substrate complementary to various optical applications.

  2. Polydopamine/Cysteine surface modified isoporous membranes with self-cleaning properties

    KAUST Repository

    Shevate, Rahul

    2017-02-03

    The major challenge in membrane filtration is fouling which reduces the membrane performance. Fouling is mainly due to the adhesion of foulants on the membrane surfaces. In this work, we studied the fouling behaviour of polystyrene-b-poly(4-vinylpyridine) (PS-b-P4VP) isoporous membrane and the mussel inspired polydopamine/L-cysteine isoporous zwitterionic membrane. Polystyrene-b-poly(4-vinylpyridine) (PS-b-P4VP) isoporous membranes were fabricated via self-assembly and non-solvent induced phase separation method. Subsequently, the isoporous membrane was modified by a mild mussel-inspired polydopamine (PDA) coating; the isoporous surface structure and the water flux was retained. Zwitterionic L-cysteine was further anchored on the PDA coated membranes via Michael addition reaction at pH 7 and 50 °C to alleviate their antifouling ability with foulants solution. The membranes were thoroughly characterized using X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), atomic force microscopy (AFM) and zeta potential measurements. Contact angle and dynamic scanning calorimetry (DSC) measurements were carried out to examine the hydrophilicity. The pH-responsive behaviour of the modified membrane remains unchanged and antifouling ability after PDA/L-cysteine functionalization was improved. The modified and unmodified isoporous membranes were tested using humic acid and natural organic matter model solutions at 0.5 bar feed pressure.

  3. Nanocomposite fibers and film containing polyolefin and surface-modified carbon nanotubes

    Science.gov (United States)

    Chu,Benjamin; Hsiao, Benjamin S.

    2010-01-26

    Methods for modifying carbon nanotubes with organic compounds are disclosed. The modified carbon nanotubes have enhanced compatibility with polyolefins. Nanocomposites of the organo-modified carbon nanotubes and polyolefins can be used to produce both fibers and films having enhanced mechanical and electrical properties, especially the elongation-to-break ratio and the toughness of the fibers and/or films.

  4. Electrokinetically driven microfluidic chips with surface-modified chambers for heterogeneous immunoassays

    NARCIS (Netherlands)

    Dodge, A.; Fluri, K.; Verpoorte, E.; De Rooij, N.F.

    2001-01-01

    This article presents the first example of a microfluidic chip for heterogeneous bioassays using a locally immobilized biospecitic layer and operated electrokinetically. The reaction chamber has picoliter dimensions and is integrated into a network of microchannels etched in glass. The high affinity

  5. XPS study of PBO fiber surface modified by incorporation of hydroxyl polar groups in main chains

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Tao; Hu Dayong; Jin Junhong; Yang Shenglin [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620 (China); Li Guang, E-mail: lig@dhu.edu.cn [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620 (China); Jiang Jianming [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620 (China)

    2010-01-15

    Dihydroxy poly(p-phenylene benzobisoxazole) (DHPBO), a modified poly(p-phenylene benzoxazole) (PBO) polymer containing double hydroxyl groups in polymer chains, was synthesized by copolymerization of 4,6-diamino resorcinol dihydrochloride (DAR), purified terephthalic acid (TA) and 2,5-dihydroxyterephthalic acid (DHTA). DHPBO fibers were prepared by dry-jet wet-spinning method. The effects of hydroxyl polar groups on the surface elemental compositions of PBO fiber were investigated by X-ray photoelectron spectroscopy (XPS). The results show that the ratio of oxygen/carbon on the surface of DHPBO fibers is higher than that on the surface of PBO fibers, which indicates the content of polar groups on the surface of DHPBO fiber increase compared with PBO fiber.

  6. Microstructure evolution and tribological properties of acrylonitrile-butadiene rubber surface modified by atmospheric plasma treatment

    Science.gov (United States)

    Shen, Ming-xue; Zhang, Zhao-xiang; Peng, Xu-dong; Lin, Xiu-zhou

    2017-09-01

    For the purpose of prolonging the service life for rubber sealing elements, the frictional behavior of acrylonitrile-butadiene rubber (NBR) surface by dielectric barrier discharge plasma treatments was investigated in this paper. Surface microstructure and chemical composition were measured by atomic force microscopy, field-emission scanning electron microscopy, and X-ray photoelectron spectroscopy, respectively. Water contact angles of the modified rubber surface were also measured to evaluate the correlation between surface wettability and tribological properties. The results show that plasma treatments can improve the properties of the NBR against friction and wear effectively, the surface microstructure and roughness of plasma-modified NBR surface had an important influence on the surface tribological behavior, and the wear depth first decreased and then increased along with the change of plasma treatment time. It was found that the wettability of the modified surface was gradually improved, which was mainly due to the change of the chemical composition after the treatment. This study suggests that the plasma treatment could effectively improve the tribological properties of the NBR surface, and also provides information for developing wear-resistant NBR for industrial applications.

  7. Poloxamer surface modified trimethyl chitosan nanoparticles for the effective delivery of methotrexate in osteosarcoma.

    Science.gov (United States)

    Li, Shenglong; Xiong, Yuyuan; Zhang, Xiaojing

    2017-06-01

    The present work is an effort to explore the poloxamer-modified trimethyl chitosan (TMC) encapsulated MTX for osteosarcoma treatment in order to improve the therapeutic efficacy and minimize severe toxicity associated with the clinical usage of MTX. The methotrexate-loaded pluronic-chitosan nanoparticles (MTCN) was nanosized and exhibited a controlled release of drug from the carrier system. The MTCN showed higher accumulation in cell cytoplasm region evident by the high red fluorescence indicating its uptake through energy-dependent endocytosis process. MTCN exhibited the increased cytotoxicity in MG63 cells compared free MTX due to its enhanced cellular uptake. Especially, MTCN exhibited a superior apoptosis effect with bright chromatin condensation and nuclear fragmentation was observed and showed remarkably higher apoptosis (∼48%) compared to that of free drug. The results of this investigation clearly demonstrate that the poloxamer-modified trimethyl chitosan (TMC) seems to have a great potential as a drug carrier in cancer chemotherapy. The present research work offers immense scope for further exploitation of poloxamer-modified trimethyl chitosan (TMC) in future for the development of nanoparticulate drug delivery system for cancer chemotherapy. Copyright © 2017. Published by Elsevier Masson SAS.

  8. Surface-Modified Nanofibrous Biomaterial Bridge for the Enhancement and Control of Neurite Outgrowth

    Science.gov (United States)

    2010-12-22

    the samples were first coated with gold using a sputter coater Hummer XP sputtering sys- tem, Anatech Ltd.. Several areas were imaged in order to...AND CONCLUSIONS Polycaprolactone nanofibers were prepared via electro- spinning and subsequently modified with ECM proteins to improve biocompatibility

  9. Surface-modified functionalized polycaprolactone scaffolds for bone repair: In vitro and in vivo experiments

    DEFF Research Database (Denmark)

    Jensen, Jonas; Rolfing, Jan Hendrik Duedal; Svend Le, Dang Quang

    2014-01-01

    -PCL). Afterward, the FDM-PCL scaffolds were infused with a mixture of PCL, water, and 1,4-dioxane and underwent a thermal-induced phase separation (TIPS) followed by lyophilization. The TIPS process lead to a nanoporous structure shielded by the printed microstructure (NSP-PCL). Sixteen Landrace pigs were divided...

  10. Nicotine-magnesium aluminum silicate microparticle surface modified with chitosan for mucosal delivery

    DEFF Research Database (Denmark)

    Kanjanakawinkul, Watchara; Rades, Thomas; Puttipipatkhachorn, Satit

    2013-01-01

    Magnesium aluminum silicate (MAS), a negatively charged clay, and nicotine (NCT), a basic drug, can interact electrostatically to form microparticles. Chitosan (CS) was used for the surface modification of the microparticles, and a lyophilization method was used to preserve the original particle...

  11. Surface Modified TiO2 Obscurants for Increased Safety and Performance

    Science.gov (United States)

    2012-11-01

    43 5.19 Corn starch 189 grams (of 200 g) launched during 0.5 second 800 psi N2 pulse...44 5.20 98% of initial mass launched during first 2 pulses for corn starch and TiO2................ 44 5.21 Aerodynamic particle size...5.12 Comparison of corn starch proxy material and TiO2 .....................................................43 5.13 Samples prepared and launched

  12. Experimental investigation of surface modified EOF steel slag as coarse aggregate in concrete

    Directory of Open Access Journals (Sweden)

    Y.K. Sabapathy

    2017-10-01

    Full Text Available An experimental work was carried out to study the effect of Energy Optimizing Furnace (EOF steel slag as coarse aggregate replacement in concrete. Surface modification of slag was carried out to seal the surface voids of raw slag aggregates. Quarry dust obtained as an extractive waste from the granite stone quarries has been used as a blending material in this work. After several trials, it was found that a mix proportion of 1:6:14 (cement:quarry dust:slag aggregate was the most suitable mix ratio for the surface modification of the slag aggregates. Various mixes of concrete were prepared with different proportions of modified slag (ranging from 0% to 100% as replacements for aggregates. Three grades of concrete (20 MPa, 30 MPa and 40 MPa were used in the investigation and the concrete mixes were evaluated for compressive strength and splitting tensile strength. It was found that the compressive strength improved for 25 percent replacement of natural coarse aggregates. The splitting tensile strength was found to peak at 25 percent replacement of natural aggregates.

  13. Electrochemical Impedance and Polarization Corrosion Studies of Tantalum Surface Modified by DC Plasma Electrolytic Oxidation

    Directory of Open Access Journals (Sweden)

    Maciej Sowa

    2018-04-01

    Full Text Available Tantalum has recently become an actively researched biomaterial for the bone reconstruction applications because of its excellent corrosion resistance and successful clinical records. However, a bare Ta surface is not capable of directly bonding to the bone upon implantation and requires some method of bioactivation. In this study, this was realized by direct current (DC plasma electrolytic oxidation (PEO. Susceptibility to corrosion is a major factor determining the service-life of an implant. Therefore, herein, the corrosion resistance of the PEO coatings on Ta was investigated in Ringer’s solution. The coatings were formed by galvanostatic anodization up to 200, 300 and 400 V, after which the treatment was conducted potentiostatically until the total process time amounted to 5 min. Three solutions containing Ca(H2PO22, Ca(HCOO2 and Mg(CH3COO2 were used in the treatment. For the corrosion characterization, electrochemical impedance spectroscopy and potentiodynamic polarization techniques were chosen. The coatings showed the best corrosion resistance at voltages low enough so that the intensive sparking was absent, which resulted in the formation of thin films. The impedance data were fitted to the equivalent electrical circuits with two time constants, namely R(Q[R(QR] and R(Q[R(Q[RW

  14. Development of Surface-Modified Polyacrylonitrile Fibers and Their Selective Sorption Behavior of Precious Metals

    Directory of Open Access Journals (Sweden)

    Areum Lim

    2016-11-01

    Full Text Available The purpose of this study was to design a powerful fibrous sorbent for recovering precious metals such as Pd(II and Pt(IV, and moreover for identifying its selectivity toward Pd(II or Pt(IV from a binary metal solution. For the development of the sorbent, polyacrylonitrile (PAN was selected as a model textile because its morphological property (i.e., thin fiber form is suitable for fast adsorption processes, and a high amount of PAN has been discharged from industrial textile factories. The PAN fiber was prepared by spinning a PAN–dimethylsulfoxide mixture into distilled water, and then its surface was activated through amidoximation so that the fiber surface could possess binding sites for Pd(II and Pt(IV. Afterwards, by Fourier-transform infrared (FT-IR and scanning electron microscopy (SEM analyses, it was confirmed that the amidoximation reaction successfully occurred. The surface-activated fiber, designated as PAN–oxime fiber, was used to adsorb and recover precious metals. In the experiment results, it was clearly observed that adsorption capacity of PAN–oxime fiber was significantly enhanced compared to the raw material form. Actually, the raw material does not have sorption capacity for the metals. In a comparison study with commercial sorbent (Amberjet™ 4200, it was found that adsorption capacity of PAN–oxime was rather lower than that of Amberjet™ 4200, however, in the aspects of sorption kinetics and metal selectivity, the new sorbent has much faster and better selectivity.

  15. Quantitative and Qualitative Analysis of Surface Modified Cellulose Utilizing TGA-MS

    Directory of Open Access Journals (Sweden)

    Daniel Loof

    2016-05-01

    Full Text Available With the aim to enhance interfacial adhesion of a hydrophobic polymer matrix and cellulosic fibers and fillers, chemical surface modifications with silane coupling agents are performed. Thermogravimetric analysis (TGA could be used to determine the degree of surface functionalization. However, similar thermal properties of treated and untreated cellulose hamper a precise determination of silane loading. This contribution deals with quantitative determination of silane loading combining both TGA and elemental analysis. Firstly, silane modified celluloses were studied by FT-IR, Raman, solid state NMR spectroscopy, and polarized light microscopy in order to determine functional groups and to study the impact of chemical treatment on cellulose morphology. Secondly, thermal stability and pyrolysis processes were studied by TG-MS analysis. In order to determine the exact silane loading, the mass percentages of the appropriate elements were quantified by elemental analysis and correlated with the charred residues determined by TGA yielding a linear dependency. With that correlation, it was possible to determine silane loadings for additional samples utilizing simple TGA measurements. The main advantage of that approach is that only one calibration is necessary for routine analyses of further samples and TGA-MS coupling gives additional information on thermal stability and pyrolysis routes, simultaneously.

  16. Adsorption of ibuprofen from aqueous solution on chemically surface-modified activated carbon cloths

    Directory of Open Access Journals (Sweden)

    Hanen Guedidi

    2017-05-01

    Full Text Available This study aims to investigate the performance of an activated carbon cloth for adsorption of ibuprofen. The cloth was oxidized by a NaOCl solution (0.13 mol L−1 or thermally treated under N2 (700 °C for 1 hour. The raw and modified cloths were characterized by N2 adsorption–desorption measurement at 77 K, CO2 adsorption at 273 K, Boehm titrations, pHPZC measurements, X-ray Photoelectron Spectroscopy analysis, and by infrared spectroscopy. The NaOCl treatment increases the acidic sites, mostly creating phenolic and carboxylic groups and decreases both the specific surface area and slightly the micropore volume. However, the thermal treatment at 700 °C under N2 induced a slight increase in the BET specific surface area and yielded to the only increase in the carbonyl group content. Ibuprofen adsorption studies of kinetics and isotherms were carried out at pH = 3 and 7. The adsorption properties were correlated to the cloth porous textures, surface chemistry and pH conditions. The isotherms of adsorption were better reproduced by Langmuir–Freundlich models at 298, 313 and 328 K. The adsorption of ibuprofen on the studied activated carbon cloths at pH 3 was an endothermic process. The pore size distributions of all studied ibuprofen-loaded fabrics were determined by DFT method to investigate the accessible porosity of the adsorbate. Both treatments do not influence the kind of micropores where the adsorption of ibuprofen occurred.

  17. Polypropylene nonwoven surface modified through introducing porous microspheres: Preparation, characterization and adsorption

    Science.gov (United States)

    Du, Xiao; Wei, Junfu; Liu, Wei; Zhou, Xiangyu; Dai, Danyang

    2016-01-01

    A new porous fabric adsorbent (PM/PP nonwoven) was prepared by hydrogen bonding self-assembly method, in which poly(divinylbenzene-co-4-vinylpyridine) microspheres were introduced onto the surface of PP-g-AA (polypropylene grafted acrylic acid) nonwoven. The effects of the main conditions for self-assembly reaction such as mass ratio of microsphere to nonwoven, pH and the grafting degree of acrylic acid were studied. In addition, the adsorption mechanisms and interactions for three VOCs (styrene, cyclohexane, acetone) were systematically elucidated. The resulting 28.2% PM/PP nonwoven obtained a higher adsorption amount (52.8 mg/g) of styrene vapor, which was 88 times greater than that of original PP nonwoven. Meanwhile, the kinetic studies suggested that the Yoon and Nelson model is suitable to describe the adsorption mechanism of styrene over the modified nonwovens. Adsorption and pressure drop data showed that PM/PP nonwoven had good adsorption ability and air permeability due to its abundant functional groups and porous structures. Taken together, it is expected that PM/PP nonwoven would be a promising adsorbent for removal of VOCs from the gas streams.

  18. Adhesion of MRC-5 and A549 cells on poly(dimethylsiloxane) surface modified by proteins.

    Science.gov (United States)

    Zuchowska, Agnieszka; Kwiatkowski, Piotr; Jastrzebska, Elzbieta; Chudy, Michal; Dybko, Artur; Brzozka, Zbigniew

    2016-02-01

    PDMS is a very popular material used for fabrication of Lab-on-a-Chip systems for biological applications. Although PDMS has numerous advantages, it is a highly hydrophobic material, which inhibits adhesion and proliferation of the cells. PDMS surface modifications are used to enrich growth of the cells. However, due to the fact that each cell type has specific adhesion, it is necessary to optimize the parameters of these modifications. In this paper, we present an investigation of normal (MRC-5) and carcinoma (A549) human lung cell adhesion and proliferation on modified PDMS surfaces. We have chosen these cell types because often they are used as models for basic cancer research. To the best of our knowledge, this is the first presentation of this type of investigation. The combination of a gas-phase processing (oxygen plasma or ultraviolet irradiation) and wet chemical methods based on proteins' adsorption was used in our experiments. Different proteins such as poly-l-lysine, fibronectin, laminin, gelatin, and collagen were incubated with the activated PDMS samples. To compare with other works, here, we also examined how ratio of prepolymer to curing agent (5:1, 10:1, and 20:1) influences PDMS hydrophilicity during further modifications. The highest adhesion of the tested cells was observed for the usage of collagen, regardless of PDMS ratio. However, the MRC-5 cell line demonstrated better adhesion than A549 cells. This is probably due to the difference in their morphology and type (normal/cancer). © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Epoxy Resins Toughened with Surface Modified Epoxidized Natural Rubber Fibers by One-Step Electrospinning.

    Science.gov (United States)

    Kim, Joo Ran; Kim, Jung J

    2017-04-27

    Epoxidized natural rubber fibers (ERFs) are developed through one-step electrospinning and directly deposited into epoxy resins without collecting and distributing of fibers. The shape of ERFs shows rough surface due to different evaporation rate of solvent mixture consisting of chloroform and dichloromethane and the average diameter of ERFs is 6.2 µm. The increase of ERFs loading from 0 to 20 wt % into the epoxy resin increases the fracture strain significantly from 1.2% to 13% and toughness from 0.3 MPa to 1.9 MPa by a factor of 7. However, the tensile strength and Young's modulus decrease about 34% from 58 MPa to 34 MPa and from 1.4 GPa to 0.9 GPa, respectively. Due to the crosslinking reactions between oxirane groups of ERFs and amine groups in the resin, surface roughness and the high aspect ratio of ERFs, ERFs result in more effective toughening effect with the minimum loss of tensile properties in epoxy resins.

  20. Epoxy Resins Toughened with Surface Modified Epoxidized Natural Rubber Fibers by One-Step Electrospinning

    Directory of Open Access Journals (Sweden)

    Joo Ran Kim

    2017-04-01

    Full Text Available Epoxidized natural rubber fibers (ERFs are developed through one-step electrospinning and directly deposited into epoxy resins without collecting and distributing of fibers. The shape of ERFs shows rough surface due to different evaporation rate of solvent mixture consisting of chloroform and dichloromethane and the average diameter of ERFs is 6.2 µm. The increase of ERFs loading from 0 to 20 wt % into the epoxy resin increases the fracture strain significantly from 1.2% to 13% and toughness from 0.3 MPa to 1.9 MPa by a factor of 7. However, the tensile strength and Young’s modulus decrease about 34% from 58 MPa to 34 MPa and from 1.4 GPa to 0.9 GPa, respectively. Due to the crosslinking reactions between oxirane groups of ERFs and amine groups in the resin, surface roughness and the high aspect ratio of ERFs, ERFs result in more effective toughening effect with the minimum loss of tensile properties in epoxy resins.

  1. REVEAL: Software Documentation and Platform Migration

    Science.gov (United States)

    Wilson, Michael A.; Veibell, Victoir T.

    2011-01-01

    The Research Environment for Vehicle Embedded Analysis on Linux (REVEAL) is reconfigurable data acquisition software designed for network-distributed test and measurement applications. In development since 2001, it has been successfully demonstrated in support of a number of actual missions within NASA's Suborbital Science Program. Improvements to software configuration control were needed to properly support both an ongoing transition to operational status and continued evolution of REVEAL capabilities. For this reason the project described in this report targets REVEAL software source documentation and deployment of the software on a small set of hardware platforms different from what is currently used in the baseline system implementation. This presentation specifically describes the actions taken over a ten week period by two undergraduate student interns and serves as an overview of the content of the final report for that internship.

  2. Omics strategies for revealing Yersinia pestis virulence

    Science.gov (United States)

    Yang, Ruifu; Du, Zongmin; Han, Yanping; Zhou, Lei; Song, Yajun; Zhou, Dongsheng; Cui, Yujun

    2012-01-01

    Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach. Mass datasets produced from omics-based studies require experts from different fields to reveal the salient features behind these data. In this review, we summarize omics-driven studies to reveal the virulence features of Yersinia pestis through genomics, trascriptomics, proteomics, interactomics, etc. These studies serve as foundations for further hypothesis-driven research and help us gain insight into Y. pestis pathogenesis. PMID:23248778

  3. Comparing SessionStateReveal and EphemeralKeyReveal for Diffie-Hellman Protocols

    Science.gov (United States)

    Ustaoglu, Berkant

    Both the "eCK" model, by LaMacchia, Lauter and Mityagin, and the "CK01" model, by Canetti and Krawczyk, address the effect of leaking session specific ephemeral data on the security of key establishment schemes. The CK01-adversary is given a SessionStateReveal query to learn session-specific private data defined by the protocol specification, whereas the eCK-adversary is equipped with an EphemeralKeyReveal query to access all ephemeral private input required to carry session computations. SessionStateReveal cannot be issued against the test session; by contrast EphemeralKeyReveal can be used against the test session under certain conditions. On the other hand, it is not obvious how EphemeralKeyReveal compares to SessionStateReveal. Thus it is natural to ask which model is more useful and practically relevant.

  4. Monosomic analysis reveals duplicated chromosomal segments in ...

    Indian Academy of Sciences (India)

    Monosomic analysis reveals duplicated chromosomal segments in maize genome. MAHESH C. YADAV1,2∗, J. K. S. ... cated chromosomal segments in maize genome. Materials and methods. Development and .... each in chromosomes 2 and 7, while 10 other pairs of du- plicate loci had one copy in chromosome 3 and the ...

  5. [Scaphoid enchondroma revealed by a fracture].

    Science.gov (United States)

    El Mrini, A; Daoudi, A; Loudyi, D; Boutayeb, F; Agoumi, O; El Yaacoubi, M

    2006-06-01

    Enchondroma is a common bone tumor of hand. It is rarely localized in scaphoid. We report a new case of this tumor revealed by fracture. The diagnosis was suggested by standard radiography and confirmed then by anatomic pathology examination. Enucleation and bone graft with osteosynthesis yielded good result.

  6. Genetic relationship among Musa genotypes revealed by ...

    African Journals Online (AJOL)

    Genetic relationship among Musa genotypes revealed by microsatellite markers. NAP Abdullah, GB Saleh, ETS Putra, ZB Wahab. Abstract. A banana germplasm was established containing 44 Musa genotypes collected from various locations in Malaysia. To detect their genetic variation and to rule out duplicates among ...

  7. Commentary: Revealing the workings of universal grammar

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 5. Commentary: Revealing the workings of universal grammar. Mohinish Shukla. Volume 28 Issue 5 September 2003 pp 535-537. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/jbsc/028/05/0535-0537. Author Affiliations.

  8. Genomics analysis of genes expressed reveals differential ...

    African Journals Online (AJOL)

    Genomics analysis of genes expressed reveals differential responses to low chronic nitrogen stress in maize. ... Most induced clones were largely involved in various metabolism processes including physiological process, organelle regulation of biological process, nutrient reservoir activity, transcription regulator activity and ...

  9. Tanzania's Revealed Comparative Advantage and Structural ...

    African Journals Online (AJOL)

    This study examines Tanzania's structural transformation by using the revealed comparative approach using export data for 2001, 2002 and 2011, at the second level of the Harmonised. System (HS). Using global data, the study finds that for 2002 and 2011, agricultural products, fish and minerals