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  1. Suresh Chand Bapna

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. Suresh Chand Bapna. Articles written in Pramana – Journal of Physics. Volume 71 Issue 6 December 2008 pp 1301-1310 Research Articles. Development of a 2 MW relativistic backward wave oscillator · Yaduvendra Choyal Lalit Gupta Prasad Deshpande Krishna Prasad ...

  2. Kapur, Prof. Prakash Chand

    Indian Academy of Sciences (India)

    Elected: 1988 Section: Engineering & Technology. Kapur, Prof. Prakash Chand Ph.D. (UC, Berkeley), FNAE. Date of birth: 3 July 1935. Specialization: Mineral Processing, Particulate Science & Technology, Mathematical Modelling and Waste Management Address: R-485, New Rajinder Nagar, New Delhi 110 060, U.T.

  3. Suresh V Vettoor

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Suresh V Vettoor. Articles written in Resonance – Journal of Science Education. Volume 8 Issue 9 September 2003 pp 41-48 General Article. Electrical Conduction and Superconductivity · Suresh V Vettoor · More Details Fulltext PDF ...

  4. M Suresh Babu

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. M Suresh Babu. Articles written in Resonance – Journal of Science Education. Volume 7 Issue 3 March 2002 pp 18-24 General Article. Operating Systems - Objectives and Evolution · M Suresh Babu · More Details Fulltext PDF. Volume 7 Issue 4 April 2002 pp ...

  5. Suresh C. Jhanwar

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Suresh C. Jhanwar. Articles written in Journal of Genetics. Volume 79 Issue 3 2000 pp 113-123. Characterization of newly established colorectal cancer cell lines: correlation between cytogenetic abnormalities and allelic deletions associated with multistep tumorigenesis · Hans Gerdes ...

  6. Confirmation that RIPK4 mutations cause not only Bartsocas-Papas syndrome but also CHAND syndrome.

    Science.gov (United States)

    Busa, Tiffany; Jeraiby, Mohammed; Clémenson, Alix; Manouvrier, Sylvie; Granados, Viviana; Philip, Nicole; Touraine, Renaud

    2017-11-01

    CHAND syndrome is an autosomal recessive disorder characterized by curly hair, ankyloblepharon, and nail dysplasia. Only few patients were reported to date. A homozygous RIPK4 mutation was recently identified by homozygosity mapping and whole exome sequencing in three patients from an expanded consanguineous kindred with a clinical diagnosis of CHAND syndrome. RIPK4 was previously known to be implicated in Bartsocas-Papas syndrome, the autosomal recessive form of popliteal pterygium syndrome. We report here two cases of RIPK4 homozygous mutations in a fetus with severe Bartsocas-Papas syndrome and a patient with CHAND syndrome. The patient with CHAND syndrome harbored the same mutation as the one identified in the family previously reported. We thus confirm the implication of RIPK4 gene in CHAND syndrome in addition to Bartsocas-Papas syndrome and discuss genotype/phenotype correlations. © 2017 Wiley Periodicals, Inc.

  7. Arikamedu: Its place in the Ancient Rome - India contacts by S. Suresh

    Digital Repository Service at National Institute of Oceanography (India)

    Tripati, S.

    & Environment, 2008. Vol. 33 (2): 113 Arikamedu: Its Place in the Ancient Rome - India Contacts S. Suresh 2007. Delhi: Embassy of Italy, Pages 126. In this book, Sethuraman Suresh has compiled available data on Arikamedu and other equally significant... scattered in various museums and institutes in India and abroad and some are even in private collections. Investigating the antiquity of Arikamedu, the author concludes that trade contacts with the Mediterranean region began in the late 3rd century B...

  8. Stochastic processes, optimization, and control theory a volume in honor of Suresh Sethi

    CERN Document Server

    Yan, Houmin

    2006-01-01

    This edited volume contains 16 research articles. It presents recent and pressing issues in stochastic processes, control theory, differential games, optimization, and their applications in finance, manufacturing, queueing networks, and climate control. One of the salient features is that the book is highly multi-disciplinary. The book is dedicated to Professor Suresh Sethi on the occasion of his 60th birthday, in view of his distinguished career.

  9. CHAND LC 4445 CAPITOL. EL TERCER VIAJE DE LE CORBUSIER A CHANDIGARH, MARZO-ABRIL 1952 / Chand LC 4445 Capitol. Third trip of Le Corbusier to Chandigarh, March-April 1952

    Directory of Open Access Journals (Sweden)

    Pere Fuertes Pérez

    2010-11-01

    Full Text Available RESUMEN El tercer viaje de Le Corbusier a Chandigarh, un año después de su primer contacto con la India, está íntimamente ligado a la definición del Capitolio en tanto que plataforma activa, capaz de poner en tensión los palacios institucionales de la que forman parte, y en tanto que realidad aislada de la ciudad y únicamente vinculada a la experiencia de las vastas dimensiones del país, al llano que la sustenta, a su techo de cielo y a las montañas que ponen fin al terreno horizontal. Durante los veinticinco días que permanece en el lugar, Le Corbusier define el Capitolio como recinto y determina sus límites, introduce la física de los reflejos combinados, intensifica la topografía como tema arquitectónico que anima la plataforma del Capitolio y dibuja los jardines que preceden al palacio del Gobernador, como síntesis de todos los temas expuestos. Los resultados darán lugar, a su vuelta, al plano con número de atelier chand lc 4445 capitol. Más adelante, a medida que se definen los palacios, el Capitolio irá modificándose para alcanzar una nueva situación de equilibrio respecto a ellos, pero siempre en relación a aquello que sucedió durante esos días de 1952. SUMMARY. The third trip of Le Corbusier to Chandigarh, a year after his first contact with India, is closely bound to the definition of the Capitol as an active platform, capable of pulling together the institutional palaces of which it forms a part and as a reality isolated from the city and uniquely linked to the experience of the vast dimensions of the country, to the plain that supports it, to its ceiling of sky and to the mountains that end the horizontal land. During the twenty-five days he stayed there, Le Corbusier defined the Capitol as an area and determined its limits. He introduced the physics of the combined reflections, intensified the topography as an architectural theme that animates the platform of the Capitol and drew the gardens that lead to the

  10. Identification of a novel mutation in RIPK4 in a kindred with phenotypic features of Bartsocas-Papas and CHAND syndromes.

    Science.gov (United States)

    Gollasch, Benjamin; Basmanav, Fitnat Buket; Nanda, Arti; Fritz, Günter; Mahmoudi, Hassnaa; Thiele, Holger; Wehner, Maria; Wolf, Sabrina; Altmüller, Janine; Nürnberg, Peter; Frank, Jorge; Betz, Regina C

    2015-11-01

    Three children from an expanded consanguineous Kuwaiti kindred presented with ankyloblepharon, sparse and curly hair, and hypoplastic nails, suggestive of CHAND syndrome (OMIM 214350) that belongs to the heterogeneous spectrum of ectodermal dysplasias. After exclusion of pathogenic mutations in TP63 we performed homozygosity mapping, followed by exome sequencing of one affected individual. We initially identified three homozygous mutations in the linked region, located in PWP2, MX2 and RIPK4. Recently, mutations in RIPK4 have been reported in Bartsocas-Papas syndrome (OMIM 263650) that shows overlapping clinical symptoms with the phenotype observed in the affected individuals studied here. Subsequent analysis of affected and non-affected family members showed that mutation c.850G>A (p.Glu284Lys) in RIPK4 was in complete segregation with the disease phenotype, in accordance with an autosomal recessive inheritance pattern, thus supporting pathogenicity of this variant. Interestingly, however, our patients did not have cleft lip/palate, a common feature encountered in Bartsocas-Papas syndrome. Whereas in Bartsocas-Papas syndromes missense mutations are usually located within the serin/threonin kinase of RIPK4, the mutation detected in our family resides just outside of the kinase domain, which could explain the milder phenotype. Our data raise the question if CHAND syndrome indeed is a distinct entity. Alternatively, CHAND and Bartsocas-Papas syndrome might be allelic disorders or RIPK4 mutations could confer varying degrees of phenotypic severity, depending on their localization within or outside functionally important domains. Our findings indicate that making an accurate diagnosis based only on the prevailing clinical symptoms is challenging. © 2015 Wiley Periodicals, Inc.

  11. Gupta, Prof. Laxmi Chand

    Indian Academy of Sciences (India)

    Specialization: Superconductivity & Magnetism in Quaternary Borocarbide and other Rare Earth based Materials, Nuclear/Magnetic Quadrupole Resonance Studies, Phenomena of Mixed Valance & Heavy Fermions Address: No. 403, Vigyanshila Co-op. Housing Society, Juhu-Varsova Link Road, Andheri (West), Mumbai ...

  12. Deshpande, Prof. Suresh Madhusudhan

    Indian Academy of Sciences (India)

    ... Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru 560 064, Karnataka Contact: Office: (080) 2208 2861. Residence: (080) 2341 2029. Mobile: 94484 71243. Fax: (080) 2208 2766. Email: smd@jncasr.ac.in, desh1942@gmail.com. http://www.jncasr.ac.in/smd/ · YouTube · Twitter · Facebook ...

  13. Das, Dr Suresh

    Indian Academy of Sciences (India)

    Specialization: Photochemistry, Photoresponsive Materials, Liquid Crystals, Photosensitizing Dyes, Photoluminiscent Materials and Photo-induced Electron Transfer Address: Executive Vice President, Kerala State Council for Science, Technology and, Environment, Sasthra Bhavan, Pattom, Thiruvananthapuram 695 004, ...

  14. Suresh, Prof. Subra

    Indian Academy of Sciences (India)

    Date of birth: 30 May 1956. Address: President, Carnegie-Mellon University, 5000, Forbes Avenue, Pittsburgh, PA 15213, U.S.A.. Contact: Office: (_1-412) 268 2200. Email: president@cmu.edu. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th ...

  15. Comparison of two association models (Elliott-Suresh-Donohue and simplified PC-SAFT) for complex phase equilibria of hydrocarbon-water and amine-containing mixtures

    DEFF Research Database (Denmark)

    Grenner, Andreas; Schmelzer, Jürgen; von Solms, Nicolas

    2006-01-01

    , and water. Furthermore, the predictive capabilities of the models are investigated for four ternary systems composed of these components, which exhibit complex liquid-liquid(-liquid) equilibria (LLLE). Various aspects of association models which have an influence in the results are studied for the PC......, both models perform overall similarly for the binary systems, although ESD shows a remarkably good behavior despite its simplicity and the use of only the two-site scheme for all associating compounds. The prediction of the LLE in the ternary systems water + octane + aniline and water + CHA + aniline......Two Wertheim-based association models, the simplified PC-SAFT and the Elliott-Suresh-Donohue (ESD) equation of state, are compared in this work for the description of vapor-liquid equilibria (VLE) and liquid-liquid equilibria (LLE) in binary systems of aniline, cyclohexylamine (CHA), hydrocarbons...

  16. Rejoinder Authors' reply to the comments made by Suresh Chandra ...

    Indian Academy of Sciences (India)

    e /4ωexe to initiate the iteration. In fact, this is same as (Y10)2/(-4Y20) employed by him to obtain the value of De. 2. He writes that the Klein integral f is given analytically by eq. (6) of his paper which, for limited Dunham's coefficients, yields. Dissociation energy, U = (Y10)2/(-4Y20). (1) or in terms of spectroscopic notations.

  17. Machine Shop I. Learning Activity Packets (LAPs). Section C--Hand and Bench Work.

    Science.gov (United States)

    Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This document contains two learning activity packets (LAPs) for the "hand and bench work" instructional area of a Machine Shop I course. The two LAPs cover the following topics: hand and bench work and pedestal grinder. Each LAP contains a cover sheet that describes its purpose, an introduction, and the tasks included in the LAP;…

  18. Suresh K. AggarwalQuantified Analysis of a Production Diesel Injector Using X-Ray Radiography and Engine Diagnostics

    Science.gov (United States)

    Ramirez, Anita I.

    The work presented in this thesis pursues further the understanding of fuel spray, combustion, performance, and emissions in an internal combustion engine. Various experimental techniques including x-ray radiography, injection rate measurement, and in-cylinder endoscopy are employed in this work to characterize the effects of various upstream conditions such as injection rate profile and fuel physical properties. A single non-evaporating spray from a 6-hole full-production Hydraulically Actuated Electronically Controlled Unit Injector (HEUI) nozzle is studied under engine-like ambient densities with x-ray radiography at the Advanced Photon Source (APS) of Argonne National Laboratory (ANL). Two different injection pressures were investigated and parameters such as fuel mass distribution, spray penetration, cone angle, and spray velocity were obtained. The data acquired with x-ray radiography is used for the development and validation of improved Computational Fluid Dynamic (CFD) models. Rate of injection is studied using the same HEUI in a single cylinder Caterpillar test engine. The injection rate profile is altered to have three levels of initial injection pressure rise. Combustion behavior, engine performance, and emissions information was acquired for three rate profile variations. It is found that NOx emission reduction is achieved when the SOI timing is constant at the penalty of lower power generated in the cycle. However, if CA50 is aligned amongst the three profiles, the NOx emissions and power are constant with a slight penalty in CO emissions. The influence of physical and chemical parameters of fuel is examined in a study of the heavy alcohol, phytol (C20H40O), in internal combustion engine application. Phytol is blended with diesel in 5%, 10%, and 20% by volume. Combustion behavior is similar between pure diesel and the phytol/diesel blends with small differences noted in peak cylinder pressure, ignition delay, and heat release rate in the premix burn phase. Diesel/phytol blends yield marginally lower power values. In-cylinder soot radiation images show combustion instability at the start of the event for the 20% phytol/diesel blend. Overall, NOx emissions are comparable across the different fuels used and no discernible trend is found in CO emissions.

  19. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. SHEFALI CHAND. Articles written in Sadhana. Volume 41 Issue 12 December 2016 pp 1393-1406. Image coding based on maximum entropy partitioning for identifying improbable intensities related to facial expressions · SEBA SUSAN NANDINI AGGARWAL SHEFALI CHAND AYUSH GUPTA.

  20. Characterization of Botrytis cinerea isolates from chickpea: DNA ...

    African Journals Online (AJOL)

    Characterization of Botrytis cinerea isolates from chickpea: DNA polymorphisms, cultural, morphological and virulence characteristics. Suresh Pande, Mamta Sharma, G. Krishna Kishore, L. Shivram, U. Naga Mangala ...

  1. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. SURESH KUMAR. Articles written in Journal of Chemical Sciences. Volume 112 Issue 6 December 2000 pp 601-605 Inorganic and Analytical. Synthesis and electrochemical studies of phenylazo substituted tetraaza macrocyclic complexes of Ni(II) · Randhir Singh Suresh ...

  2. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. SURESH D SHIRBAHADURKAR. Articles written in Sadhana. Volume 43 Issue 3 March 2018 pp 38. FWFusion: Fuzzy Whale Fusion model for MRI multimodal image fusion · HANMANT VENKETRAO PATIL SURESH D SHIRBAHADURKAR · More Details Abstract Fulltext PDF. Medical treatment ...

  3. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Suresh Parameshwar Nayak. Articles written in Journal of Chemical Sciences. Volume 127 Issue 11 November 2015 pp 1977-1991 Articles. A new synthesis of Entacapone and report on related studies · Attimogae Shivamurthy Harisha Suresh Parameshwar Nayak Pavan ...

  4. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. Suresh Kumar. Articles written in Pramana – Journal of Physics. Volume 67 Issue 2 August 2006 pp 369-374 Brief Reports. Proton and alpha evaporation spectra in low energy 12C andO induced reactions · E T Mirgle D R Chakrabarty V M Datar Suresh Kumar A Mitra H H ...

  5. Focus Area Science Technology Summer Fellowship (FAST-SF)

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  6. Forthcoming Articles | Pramana – Journal of Physics | Journals ...

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  7. 10-Associateship | 3-Fellowship | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  8. 94440 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  9. 98692 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  10. 93412 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  11. 99007 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  12. 99782 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  13. 94498 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  14. 99306 | php | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Chattoo Vijay Kumar Sharma Ahmed Hassan Zewail Sailendranath Roy Chaudhury Mangalore Vivekananda Bhatt Bahadur Chand Nakra Noshir Hormusji Wadia Charusita Chakravarty Paramasivam Natarajan Manoj Kumar Pal Chirayathumadom Venkatachalier Subramanian Deepak Kumar Subramania Ranganathan.

  15. Barber. Symphony N 1, Op. 9 / Michael Oliver

    Index Scriptorium Estoniae

    Oliver, Michael

    1991-01-01

    Uuest heliplaadist "Barber. Symphony N 1, Op. 9. The School for Scandal Overture, Op. 5 Beach. Symphony in E minor, Op. 32, "Gaelic". Detroit Symphony Orchestra /Neeme Järvi" Chandes cassette ABTD 1550; CD CHAN 8958 (72 minutes)

  16. Automatic recognition of printed Oriya script

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Some studies have been reported on Tamil, Telugu and. Gurmukhi scripts ..... leaf node, giving rise to recognition errors. The contribution of these ... As a native speaker of Oriya, Anil Chand gave us useful advice about the script. P. Sashank.

  17. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ground tree outside forest (TOF) phytomass and carbon estimation in the semiarid region of southern Haryana: A synthesis approach of remote sensing and field data. Kuldeep Singh Pritam Chand. Volume 121 Issue 6 December 2012 pp 1469- ...

  18. Comment on “Observations of ammonia, nitric acid, and fine particles in a rural gas production region” by Yi Li, Florian M. Schwandnera, H. James Sewell, Angela Zivkovich, Mark Tigges, Suresh Raja, Stephen Holcomb, John V. Molenar, Lincoln Sherman, Cassie Archuleta, Taehyoung Lee and Jeffrey L. Collett Jr. Atmospheric Environment (in press)

    Science.gov (United States)

    Phillips, Gavin J.

    2014-05-01

    An artefact of the detection of nitric acid (HNO3) by denuder methods is discussed. This artefact arises from the likely reaction of dinitrogen pentoxide (N2O5) on the denuder train resulting in the report of some fraction of N2O5 as HNO3.

  19. Neuromorphic olfaction neuromorphic olfaction

    CERN Document Server

    Persaud, Krishna C; Marco, Santiago

    2016-01-01

    Engineering Aspects of Olfaction; Krishna C. PersaudStudy of the Coding Efficiency of Populations of OlfactoryReceptor Neurons and Olfactory Glomeruli; Agustín Gutiérrez-Gálvez and Santiago MarcoMimicking Biological Olfaction with Very Large ChemicalArrays; Mara Bernabei, Romeo Beccherelli, Emiliano Zampetti,Simone Pantalei, and Krishna C. PersaudThe Synthetic Moth: A Neuromorphic Approach towardArtificial Olfaction in Robots; Vasiliki Vouloutsi, Lucas L. Lopez-Serrano,Zenon Mathews, Alex Escuredo Chimeno, Andrey Ziyatdinov, Alexandre Perera i Lluna, Sergi Bermúdez i Badia, and Paul F. M. J. Verschure Reactive and Cognitive Search Strategies for Olfactory Robots; Dominique Martinez and Eduardo Martin MoraudPerformance of a Computational Model of the MammalianOlfactory System; Simon Benjaminsson, Pawel Herman, and Anders LansnerIndex.

  20. Financial market´s appetite for risk: and the challenge of assessing its evolution by risk appetite indicators

    OpenAIRE

    Uhlenbrock, Birgit

    2009-01-01

    Assessments of investors' risk appetite/aversion stance via indicators often yields results which seem unsatisfactory (see e.g. Illing and Aaron (2005)). Understanding how such indicators work therefore seems essential for further improvements. The present paper seeks to contribute to this evolution, focusing on the Global Risk Appetite Index (GRAI) class of indicators going back to Kumar and Persaud (2002). Looking at international stock indices during the subprime crisis in 2007, the plausi...

  1. Operating Systems

    Indian Academy of Sciences (India)

    Functions, Protection and Security Mechanisms. M Suresh ... execution. To improve the utilization of central processing unit ... allocated to the process either when it is created or while it is executing. .... techniques: segmentation and paging.

  2. Thyroglobulin – what is the postoperative threshold for the suspicion ...

    African Journals Online (AJOL)

    2% of all malignancies in women and men, respectively, and is responsible ... 1st Department of Surgery, University General Hospital of Alexandroupolis, Greece ..... Memon A, Berrington De González A, Luqmani Y, Suresh A. Family history.

  3. Fulltext PDF

    Indian Academy of Sciences (India)

    , Vidyadhar Y Mudkavi, Gautam N adig, Harini. Nagendra, K H Paranjape, VPati, Lara Patwardhan, C R Pranesachar,. Girish Ratnaparkhi, J ayant Rao, V Ravi, Diptiman Sen, U rna. Subbaramu, Stephen Suresh, B J Venkatachala. Our special ...

  4. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Sharat Chandra (both of Indian Institute of Science, Bengaluru) and Suresh Jayakar ... In 1985, the Indian Academy of Sciences, Bengaluru, revived publication of ... It publishes papers and review articles on current topics, commentaries and ...

  5. Fatigue crack growth retardation in spot heated mild steel sheet

    Indian Academy of Sciences (India)

    Unknown

    Department of Metallurgical Engineering, *Department of Applied Mechanics and Hydraulics, ... growth retardation increases with increasing level of overload as well as with ..... Suresh S 1996 Fatigue of materials (Cambridge: Cambridge.

  6. 73th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

    Indian Academy of Sciences (India)

    Symposium: Space sciences and applications -- current trends and future perspectives (Convener: R. ... 15.00 - 15.30. B. N. SURESH, Vikram Sarabhai Space Centre, Thiruvananthapuram Space .... Access To [All] Knowledge. Posted on 24 ...

  7. The great tsunami of 26 December 2004: A description based on tide gauge data from Indian subcontinent and surrounding areas

    Digital Repository Service at National Institute of Oceanography (India)

    Nagarajan, B.; Suresh, I; Sundar, D.; Sharma, R; Lal, A.K.; Neetu, S.; Shenoi, S.S.C.; Shetye, S.R; Shankar, D.

    -1 Earth Planets Space, 58, 211?215, 2006 The Great Tsunami of 26 December 2004: A description based on tide-gauge data from the Indian subcontinent and surrounding areas B. Nagarajan1, I. Suresh2, D. Sundar2, R. Sharma1,A.K.Lal1, S. Neetu2, S. S. C. Shenoi..., I. Suresh, D. Sundar, R. Sharma, A. K. Lal, S. Neetu, S. S. C. Shenoi, S. R. Shetye, and D. Shankar (e-mail: shankar@nio.org) ...

  8. Bipartite Anterior Extraperitoneal Teratoma: Evidence for the Embryological Origins of Teratomas?

    Directory of Open Access Journals (Sweden)

    D. J. B. Keene

    2011-01-01

    Full Text Available Teratomas are thought to arise from totipotent primordial germ cells (PGCs Dehner (1983 which may miss their target destination Moore and Persaud (1984. Teratomas can occur anywhere from the brain to the coccygeal area but are usually in the midline close to the embryological position of the gonadal ridges Bale (1984, Nguyen and Laberge (2000. We report a case of a bipartite anterior extraperitoneal teratoma. This is an unusual position for a teratoma, but one which may support the “missed target” theory of embryology.

  9. Role of land state in a high resolution mesoscale model for ...

    Indian Academy of Sciences (India)

    13

    2015-10-02

    Oct 2, 2015 ... School of Earth, Ocean and Climate Sciences ... Though global models predicted the large scale event, but they had failed to predict realistic ... this study is to assess the impact of land state conditions in ...... Chand, R and C Singh 2015 Movements of western disturbance and associated cloud convection J.

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    assisted pyramiding of Thinopyrum -derived leaf rust resistance genes Lr19 and Lr24 in bread wheat variety HD2733 · MONA SINGH N. MALLICK S. CHAND P. KUMARI J. B. SHARMA M. SIVASAMY P. JAYAPRAKASH K. V. PRABHU S. K. JHA ...

  11. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    Elected: 1995 Section: Engineering & Technology. Nakra, Prof. Bahadur Chand Ph.D. (London), FNA, FNAE, FNASc. Date of birth: 31 March 1939. Date of death: 12 April 2016. Specialization: Vibration Engineering, System Dynamics & Controls and Instrumentation, Mechatronics Last known address: P-12, New Colony, ...

  12. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. SEBA SUSAN. Articles written in Sadhana. Volume 41 Issue 12 December 2016 pp 1393-1406. Image coding based on maximum entropy partitioning for identifying improbable intensities related to facial expressions · SEBA SUSAN NANDINI AGGARWAL SHEFALI CHAND AYUSH GUPTA.

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Bulletin of Materials Science; Volume 36; Issue 4. Magnetic resonance in superparamagnetic zinc ferrite. Jitendra Pal Singh Gagan Dixit R C Srivastava Hemant Kumar H M Agrawal Prem Chand. Volume 36 Issue 4 August 2013 pp 751-754 ...

  14. S A R Hashmi

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. S A R Hashmi. Articles written in Bulletin of Materials Science. Volume 26 Issue 6 October 2003 pp 579-583 Tribological Materials. Role of PET in improving wear properties of PP in dry sliding condition · Somit Neogi S A R Hashmi Navin Chand · More Details Abstract Fulltext ...

  15. Preliminary Design of an Automated White Board Cleaner

    African Journals Online (AJOL)

    Toshiba

    sucking force of the fan opening the lower end of the absorbing head so that the wiped .... The following are the advantages and disadvantages of chain drive over belt drive. ... Chand and company, New Delhi., pg 560-577. Vol. 8 (2) Serial No.

  16. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 79; Issue 2. Issue front cover thumbnail. Volume 79, Issue 2. August 2012, pages 173-335. pp 173-183. Complex dynamical invariants for two-dimensional complex potentials · J S Virdi F Chand C N Kumar S C Mishra · More Details Abstract Fulltext PDF. Complex ...

  17. Barber: Sinfonie Nr. 1, Op. 9, Neeme Järvi / Bernhard Uske

    Index Scriptorium Estoniae

    Uske, Bernhard

    1991-01-01

    Uuest heliplaadist "Barber: Sinfonie Nr. 1, Op. 9. Ouvertüre School for Scandal, Op. 5; Beach: Sinfonie e-Moll, Op. 32, "Gaelic". Detroit Symphony Orchestra /Neeme Järvi". Chandes cassette ABTD 1550; CD CHAN 8958 (72 minutes)

  18. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Interestingly, the integrals of motion in the new coordinates turn out to be the desired invariants of the systems. Volume 72 Issue 4 April 2009 pp 647-654 Research Articles. The solution of the Schrödinger equation for coupled quadratic and quartic potentials in two dimensions · Ram Mehar Singh Fakir Chand S C Mishra.

  19. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Marker-assisted pyramiding of Thinopyrum -derived leaf rust resistance genes Lr19 and Lr24 in bread wheat variety HD2733 · MONA SINGH N. MALLICK S. CHAND P. KUMARI J. B. SHARMA M. SIVASAMY P. JAYAPRAKASH K. V. PRABHU S. K. JHA VINOD · More Details Abstract Fulltext PDF. This study was undertaken ...

  20. African Journal of Paediatric Surgery - Vol 11, No 3 (2014)

    African Journals Online (AJOL)

    Oesophageal foreign body in children: 15 years experience in a tertiary care paediatric centre · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A Singh, M Bajpai, SS Panda, K Chand, M Jana, A Ali, 238-241 ...

  1. Self-assembly of self-assembled molecular triangles

    Indian Academy of Sciences (India)

    SB/S1/IC-05/2014) for providing financial support to our research endeav- ours. We gratefully acknowledge the single crystal X- ray diffractometer facility funded by IIT Madras. References. 1. (a) Cook T R, Zheng Y-R and Stang P J 2013 Chem. Rev. 113 734; (b) Debata N B, Tripathy D and Chand. D K 2012 Coord. Chem.

  2. Controlled size and one-dimensional growth

    Indian Academy of Sciences (India)

    875–881. c Indian Academy of Sciences. Synthesis of azamacrocycle stabilized palladium nanoparticles: Controlled size and one-dimensional growth. JEYARAMAN ATHILAKSHMI and DILLIP KUMAR CHAND. ∗. Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, India e-mail: dillip@iitm.ac.

  3. Genetic variation and population structure in Oryza ...

    Indian Academy of Sciences (India)

    Oryza malampuzhaensis Krish. et Chand. ( 2 n = 4 x = 48 ; Poaceae, Oryza) is endemic to Western Ghats, South India, and shows a highly localized distribution over a small geographical area in this region. This is the most poorly understood taxon in genus Oryza and is often misidentified as O. officinalis owing to their close ...

  4. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. P Pant. Articles written in Journal of Earth System Science. Volume 117 Issue S1 July 2008 pp 303-313. Characteristics of spectral aerosol optical depths over India during ICARB · S Naseema Beegum K Krishna Moorthy Vijayakumar S Nair S Suresh Babu S K Satheesh V ...

  5. Search for an interstellar Si2C molecule: A theoretical prediction

    Indian Academy of Sciences (India)

    63, No. 3. — journal of. September 2004 physics pp. 627–631. Search for an interstellar Si2C molecule: A theoretical prediction. SURESH CHANDRA. School of ... top molecule as its electric dipole moment µ lies along the axis of intermediate moment of inertia. Because of differences between the molecular parameters of.

  6. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. C B S Dutt. Articles written in Journal of Earth System Science. Volume 117 Issue S1 July 2008 pp 243-262. Integrated Campaign for Aerosols, gases and Radiation Budget (ICARB): An overview · K Krishna Moorthy S K Satheesh S Suresh Babu C B S Dutt · More Details ...

  7. SUPPLEMENTARY INFORMATION Molecular electrostatic potential ...

    Indian Academy of Sciences (India)

    Sandhya K S

    PADINJARE VEETIL BIJINA and CHERUMUTTATHU H SURESH. Chemical Sciences and Technology Division and Academy of Scientific & Innovative Research (AcSIR), CSIR-National Institute for Interdisciplinary Science and Technology, Trivandrum 695019, India. Email: sureshch@gmail.com. # Celebrating 100 years ...

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. K Suresh1 N V Poornachandra Rao2 K V R Murthy3. Department of Physics, CSR Sarma College, Ongole 523 001, India; Department of Physics, Rajiv Gandhi University of Knowledge Technologies, IIIT, Basara 504 101, India; Department of Applied Physics, Faculty of Engineering and Technology, M.S. ...

  9. Fulltext PDF

    Indian Academy of Sciences (India)

    68 Fascinating Shapes and Strudures Due to Entropic. Forces. Kheyo Sengupta and Kattero A Suresh. 73 Adaptive Significance of Circadian Rhythms. Biological Clocks andDarwinian Fitness in Cyanobacteria. V Sheeba, Vijoy Kumar Sharma and Amitabh Joshi. BOOK REVIEWS. 76 Ex-Prodigy, My Childhood and Youth.

  10. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Volume 40 Issue 2 April 2015 pp 605-622 Mechanical Sciences. Thermal front propagation in variable aperture fracture-matrix ... 2015 pp 2429-2455. Experimental and numerical investigations on nitrogen species transport in unsaturated soil during various irrigation patterns · M Berlin Indumathi M Nambi G Suresh Kumar.

  11. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 1. Do Trees Tell About the Past? H S Suresh. General Article Volume 17 Issue 1 January 2012 pp 33-43. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/017/01/0033-0043. Keywords.

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Sandeep Arya. Articles written in Bulletin of Materials Science. Volume 36 Issue 4 August 2013 pp 535-539. Synthesis of copper telluride nanowires using template-based electrodeposition method as chemical sensor · Sandeep Arya Saleem Khan Suresh Kumar Rajnikant ...

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. SURESH KUMAR. Articles written in Bulletin of Materials Science. Volume 35 Issue 5 October 2012 pp 787-794. Electrical transport and EPR investigations: A comparative study for d.c. conduction mechanism in monovalent and multivalent ions doped polyaniline.

  14. Rajnikant

    Indian Academy of Sciences (India)

    Synthesis of copper telluride nanowires using template-based electrodeposition method as chemical sensor · Sandeep Arya Saleem Khan Suresh Kumar Rajnikant Verma Parveen Lehana · More Details Abstract Fulltext PDF. Copper telluride (CuTe) nanowires were synthesized electrochemically from aqueous acidic ...

  15. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 2. Nature's Solar Cell. Stephen Suresh Gautham Nadig. Research News Volume 1 Issue 2 February 1996 pp 102-104. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/001/02/0102-0104 ...

  16. Gautham Nadig

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Gautham Nadig. Articles written in Resonance – Journal of Science Education. Volume 1 Issue 2 February 1996 pp 102-104 Research News. Nature's Solar Cell · Stephen Suresh Gautham Nadig · More Details Fulltext PDF ...

  17. Associateship | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Fellowship; Associateship. Associate Profile. Period: 2007–2011. Suresh Babu, Dr S. Date of birth: 14 March 1976. Address during Associateship: Space Physics Laboratory, Vikram Sarabhai Space Centre, Thiruvananthapuram - 695 022. Contact: Email: s_sureshbabu@vssc.gov.in. YouTube; Twitter; Facebook ...

  18. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 119; Issue 2. Volume 119, Issue 2. April 2010, pages 137-228. pp 137-145. Effect of co-operative fuzzy c-means clustering on estimates of three parameters AVA inversion · Rajesh R Nair Suresh Ch Kandpal · More Details Abstract Fulltext PDF. We determine the ...

  19. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. Suresh Chandra Kandpal. Articles written in Journal of Earth System Science. Volume 120 Issue 5 October 2011 pp 873-883. Subsurface signatures and timing of extreme wave events along the southeast Indian coast · Rajesh R Nair Madhav K Murari C S Vijaya Lakshmi ...

  20. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Substrate integrated Lead-Carbon hybrid ultracapacitor with flooded, absorbent glass mat and silica-gel electrolyte configurations · A Banerjee M K Ravikumar A Jalajakshi P Suresh Kumar S A Gaffoor A K Shukla · More Details Abstract Fulltext PDF. Lead-Carbon hybrid ultracapacitors (Pb-C HUCs) with flooded, ...

  1. Synthesis and structural characterization of a calcium coordination ...

    Indian Academy of Sciences (India)

    Synthesis and structural characterization of a calcium coordination polymer based on a μ3-bridging. tetradentate binding mode of glycine. SUBRAMANIAN NATARAJAN*a, BIKSHANDARKOIL R. SRINIVASANb , J. KALYANA SUNDARa, K. RAVIKUMARc , R.V. KRISHNAKUMARd , J. SURESHe,. aSchool of Physics, ...

  2. 15-00506_SI.docx

    Indian Academy of Sciences (India)

    User

    HARINATH YAPATIa, SUBBA RAO DEVINENIb, SURESH CHIRUMAMILLAa and SESHAIAH KALLURUa,*. aInorganic and Analytical Chemistry Division, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India. bResearch and Development Centre, Micro Labs Ltd., API Division, Bommasandra-Jigini Link ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. AGASTHYA SURESH. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 75-83 Article. PAX6 can substitute for LHX2 and override NFIA-induced astrogliogenesis in developing hippocampus in vivo · VEENA KINARE ASHWIN S SHETTY AGASTHYA ...

  4. Saleem Khan

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Saleem Khan. Articles written in Bulletin of Materials Science. Volume 36 Issue 4 August 2013 pp 535-539. Synthesis of copper telluride nanowires using template-based electrodeposition method as chemical sensor · Sandeep Arya Saleem Khan Suresh Kumar Rajnikant ...

  5. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    High spectral response heteroleptic ruthenium (II) complexes as sensitizers for dye sensitized solar cells · M Chandrasekharam Ch Srinivasarao T Suresh M Anil Reddy M Raghavender G Rajkumar M Srinivasu P Yella Reddy · More Details Abstract Fulltext PDF. Heteroleptic ruthenium(II) bipyridyl complex, cis-Ru(II)(4 ...

  6. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Synthesis, characterization and studies on antioxidant and molecular docking of metal complexes of 1-(benzo[d]thiazol-2-yl)thiourea · Harinath Yapati Subba Rao Devineni Suresh Chirumamilla Seshaiah Kalluru · More Details Abstract Fulltext PDF. In the present study, a new thiourea derivative bearing benzothiazole ...

  7. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. Santosh Kumar. Articles written in Journal of Earth System Science. Volume 117 Issue S1 July 2008 pp 303-313. Characteristics of spectral aerosol optical depths over India during ICARB · S Naseema Beegum K Krishna Moorthy Vijayakumar S Nair S Suresh Babu S K ...

  8. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 4. Operating Systems - Functions, Protection and Security Mechanisms. M Suresh Babu. General Article Volume 7 Issue 4 April 2002 pp 60-66. Fulltext. Click here to view fulltext PDF. Permanent link:

  9. Operating Systems-Objectives and Evolution

    Indian Academy of Sciences (India)

    M Suresh Babu1. C/o N Sudhakar Reddy D. No. 16-3-1141F Pinaki Nagar Haranathapuram IV line Nellore 524003 Andhra Pradesh, India. Resonance – Journal of Science Education. Current Issue : Vol. 23, Issue 4 · Current Issue Volume 23 | Issue 4. April 2018. Home · Volumes & Issues · Categories · Special Issues ...

  10. Fulltext PDF

    Indian Academy of Sciences (India)

    GENERAL ARTICLES. 10 Asymmetry In Nature - Discrete Symmetries In. Particle Physics and their Violation. Background and Parity Violation. B Ananthanarayan, J Meeraa, Bharti Sharma,. Seema Sharma and Ritesh K Singh. 18 Operating Systems. Obiectives and Evolution. M Suresh Babu. 25 Markov Chain Monte Carlo.

  11. SUPPLEMENTARY INFORMATION Dimethylglyoxime as an ...

    Indian Academy of Sciences (India)

    lenovo

    1. SUPPLEMENTARY INFORMATION. Dimethylglyoxime as an Efficient Ligand for Copper-Catalyzed Hydroxylation of Aryl. Halides. SURESH S SHENDAGE*. Department of Chemistry, KET'S Vinayak Ganesh Vaze College of Arts, Science and. Commerce, Mithagar Road, Mulund (E) Mumbai, Maharashtra 400 081, India.

  12. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Indumathi M Nambi. Articles written in Sadhana. Volume 39 Issue 6 December 2014 pp 1387-1408. Numerical modelling of multicomponent LNAPL dissolution kinetics at residual saturation in a saturated subsurface system · M Vasudevan G Suresh Kumar Indumathi M Nambi · More Details ...

  13. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    DNA binding and cleavage activity by a mononuclear iron(II)Schiff base complex: Synthesis and structural characterization. Abhijit Pal Bhaskar Biswas Merry Mitra Subramaniyam Rajalakshmi Chandra Shekhar Purohit Soumitra Hazra Gopinatha Suresh Kumar Balachandran Unni Nair Rajarshi Ghosh. Volume 125 Issue 5 ...

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Syntheses, characterization and crystal structures of potassium and barium complexes of a Schiff base ligand with different anions. Bhavesh Parmar Kamal Kumar Bisht Pratyush Maiti Parimal Paul Eringathodi Suresh. Special issue on Chemical Crystallography Volume 126 Issue 5 September 2014 pp 1373-1384 ...

  15. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 120; Issue 6. Anthropogenic and impact spherules: Morphological similarity and chemical distinction – A case study from India and its implications. Ambalika Niyogi Jayanta K Pati Suresh C Patel Dipak Panda Shiv K Patil. Volume 120 Issue 6 December 2011 pp ...

  16. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Metal organic framework MIL-101(Cr) for dehydration reactions · M Suresh B David Raju K S Rama Rao K Raveendranath Reddy M Lakshmi Kantam Pavuluri Srinivasu · More Details Abstract Fulltext PDF. Porous chromium terephthalate MIL-101 (Cr-MIL-101) has been prepared by direct method under hydrothermal ...

  17. Resonance journal of science education

    Indian Academy of Sciences (India)

    July 2011 Volume 16 Number 7. GENERAL ARTICLES. 606 Hermann Emil Fischer: Life and Achievements. G Nagendrappa. 620 Carbohydrate Chemistry from Fischer to Now. N R Krishnaswamy. 640 One Hundred Years of Peptide Chemistry. V V Suresh Babu. 648 Fermat: A Versatile Genius. Utpal Mukhopadhyay. O. HO.

  18. Flow Over a Body of Revolution in a Steady Turn

    Science.gov (United States)

    2004-10-01

    31], Migliore and Wolfe [32]. Migliore investigated flow curvature effects on Darrieus wind turbines , a special type of turbine which has a continuous...and Wolfe- J. B.. Some Effects of Flow Curvature Effects oil the Aerodynamics of Darrieus Wind Turbines West Viryinia University , 1979 33. Hirsch, Ch...and Mandal. A. C., Flow Curvature Effects on Vertical Axis Darrieus Wind Turbine Having High Chord-Radius Ratio European Wind Energy Confer- ence

  19. Rotating Beam Fatigue Testing and Hybrid Ceramic Bearings.

    Science.gov (United States)

    1994-07-01

    Runout and Fast Fracture ......... 20 FIG.7 Stress-life Plots of Rotating Beam Fatigue Testing ............. 23 FIG.8 Fractograph of Rotating Beam...Chand-Kare Engineering Ceramics, Worcester, MA. Diamond wheels of 600 grits were used with longitudinal grinding applied for the final finishing of...stress in the range of 600-850 MPa. Three test completion modes were encountered, i.e. fast fracture at setup, fatigue fracture and runout (no failure

  20. 2075-IJBCS -Article-Maurice Ognalaga

    African Journals Online (AJOL)

    hp

    Leucaena leucocephalae et de C. odorata. Ils ont attribué cette réaction à la richesse chimique de ces deux engrais verts utilisés. De nombreux autres travaux comme ceux de. Choudhary et Suresh (2013) affirment que les amendements organiques libèrent lentement les nutriments dans le sol. En somme, il s'agirait d'une ...

  1. Fatigue 󈨛. Volume 2,

    Science.gov (United States)

    1987-06-01

    ROLAND STICKLER Absolute Fatigue Thresholds in Metallic 801 Materials - J.A. LEWIS Thermometrical Investigations on the Near 809 Threshold Fatigue...impurities reported by Semi- Alloys Inc. totaled less than 0.1%. Specimens were cast in a flat open aluminum mold. Each specimen was 6 mm thick and 12...and 2024-T351 Aluminum Alloy", in "Fatigue Crack Growth Threshold Concepts", D.L. Davidson, S. Suresh, editors, TMS-AIME. 1984, pp. 63-82. (2) Bailon

  2. Steam coal markets forum - the buyers` outlook

    Energy Technology Data Exchange (ETDEWEB)

    Graybeal, W.R.; Costa, D.; Iyer, S.; Perego, G. [Apex Resources Group (United States)

    1996-12-31

    The session contains four presentations: a talk on the uncertain future of coal, by Bill Graybeal of Apex Resources Group; a talk on coal procurement at the Sines power plant in Portugal, by Duarte Costa of CPPE-EDP group, Portugal; a presentation by Suresh Iyer of NEPCO on coal at the New England Power Company; and a paper by Giovanni Perego of ENEL Spa, Italy on coal imports and coal use by ENEL.

  3. Melioidosis in acute cholangitis of diabetic patient: a forgotten diagnosis

    OpenAIRE

    Mohamad, Nasir; Ponnusamy,Suresh; Devi,Sunita; Manikam,Rishya; Idrus,Ilya Irinaz; Hidayah Binti Abu Bakar,Nor

    2012-01-01

    Nasir Mohamad,1 Suresh Ponnusamy,2 Sunita Devi,3 Rishya Manikam,4 Ilya Irinaz Idrus,1 Nor Hidayah Abu Bakar51Department of Emergency Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia; 2AIMST University, Bedong, Malaysia; 3Hospital Sultan Abdul Halim, Sungai Petani, Malaysia; 4University Malaya Medical Centre, Kuala Lumpur, Malaysia; 5Department of Pathology, Hospital Raja Perempuan Zainab II, Kota Bharu, MalaysiaAbstract: Melioidosis presents with a wide...

  4. An Animal-to-Human Scaling Law for Blast-Induced Traumatic Brain Injury Risk Assessment

    Science.gov (United States)

    2014-10-28

    human injury risk would be of critical importance for guiding the design of blast- protective helmets and face shields. Materials and Methods ...Biomedical Imaging (IEEE, Piscataway, NJ), Vol 53, pp 1142–1145. 39. Prevost TP, Balakrishnan A, Suresh S, Socrate S (2011) Biomechanics of brain tissue. Acta...3006–3012. 51. El Sayed T, Mota A, Fraternali F, Ortiz M (2008) Biomechanics of traumatic brain in- jury. Comput Methods Appl Mech Eng 197(51–52):4692

  5. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Superconducting linear accelerator system for NSC · P N Prakash T S Datta B P Ajith Kumar J Antony P Barua J Chacko A Choudhury G K Chadhari S Ghosh S Kar S A Krishnan Manoj Kumar Rajesh Kumar A Mandal D S Mathuria R S Meena R Mehta K K Mistri A Pandey M V Suresh Babu B K Sahu A Sarkar S S K Sonti A ...

  6. Isotropy of quadratic forms

    Indian Academy of Sciences (India)

    V. Suresh University Of Hyderabad Hyderabad

    2008-10-31

    Oct 31, 2008 ... We say that (a1,··· ,an) is a zero of the polynomial f if f (a1,··· ,an) = 0. One of the main problems in Mathematics is to determine whether the given polynomial has a (non-trivial) zero or not. For example, let us recall the Fermat's last theorem: V. Suresh University Of Hyderabad Hyderabad. Isotropy of quadratic ...

  7. Inquiring into Appreciative Inquiry: A Conversation With David Cooperrider and Ronald Fry

    OpenAIRE

    Grieten, Styn; Lambrechts, Frank; Bouwen, René; Huybrechts, Jolien; Fry, Ronald; Cooperrider, David

    2018-01-01

    David Cooperrider and Ronald Fry are professors of Organizational Behavior at the Weatherhead School of Management, Case Western Reserve University. CWRU’s Department of Organizational Behavior is consistently acknowledged as one of the best in the world by the Financial Times. Together with their mentor, Suresh Srivastva, they created Appreciative Inquiry over 30 years ago. Since then, Appreciative Inquiry has been extensively applied world-wide, and many exciting results have been achieved ...

  8. Inequality and ethics in paediatric HIV remission research: From Mississippi to South Africa and back.

    Science.gov (United States)

    Crane, Johanna T; Rossouw, Theresa M

    2017-02-01

    In 2013, physician-researchers announced that a baby in Mississippi had been 'functionally cured' of HIV [Persaud, D., Gay, H., Ziemniak, C. F., Chen, Y. H., Piatak, M., Chun, T.-W., … Luzuriaga, K. (2013b, March). Functional HIV cure after very early ART of an infected infant. Paper presented at the 20th conference on retroviruses and opportunistic infections, Atlanta, GA]. Though the child later developed a detectable viral load, the case remains unprecedented, and trials to build on the findings are planned [National Institute of Allergy and Infectious Diseases. (2014). 'Mississippi baby' now has detectable HIV, researchers find. Retrieved from http://www.niaid.nih.gov/news/newsreleases/2014/pages/mississippibabyhiv.aspx ]. Whether addressing HIV 'cure' or 'remission', scrutiny of this case has focused largely on scientific questions, with only introductory attention to ethics. The social inequalities and gaps in care that made the discovery possible - and their ethical implications for paediatric HIV remission - have gone largely unexamined. This paper describes structural inequalities surrounding the 'Mississippi baby' case and a parallel case in South Africa, where proof-of-concept studies are in the early stages. We argue that an ethical programme of research into infant HIV remission ought to be 'structurally competent', and recommend that paediatric remission studies consider including a research component focused on social protection and barriers to care.

  9. Origins of wind-driven intraseasonal sea level variations in the North Indian Ocean coastal waveguide

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, I.; Vialard, J.; Lengaigne, M.; Han, W.; Mc; Durand, F.; Muraleedharan, P.M.

    version: Geophys. Res. Lett., vol.40(21); 2013; 5740-5744 Origins of wind-driven intraseasonal sea level variations in the North Indian Ocean coastal waveguide I. Suresh1, J. Vialard2, M. Lengaigne2, W. Han3, J. McCreary4, F. Durand5, P.M. Muraleedharan1... reversing winds. These wind variations drive seasonal equatorial Kelvin and Rossby wave responses. The seasonal equatorial Kelvin waves propagate into the North Indian Ocean (hereafter NIO) as coastal Kelvin waves [McCreary et al., 1993]. As a result...

  10. Dominant role of winds near Sri Lanka in driving seasonal sea level variations along the west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, I.; Vialard, J.; Izumo, T.; Lengaigne, M.; Han, W.; Mc; Muraleedharan, P.M.

    version: Geophys. Res. Lett.: 43(13); 2016; 7028-7035 Dominant role of winds near Sri Lanka in driving seasonal sea-level variations along the west coast of India I. Suresh1, J. Vialard2, T. Izumo2,3, M. Lengaigne,2,3, W. Han4, J. McCreary5, P... as manifested both in sea level and surface circulation of the North Indian Ocean (NIO) [e.g., Schott and McCreary, 2001]. The sea level along the west coast of India (WCI), in particular, is dominated by the seasonal cycle. Figure 1a, which shows...

  11. Minima of interannual sea-level variability in the Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Shankar, D.; Aparna, S.G.; Mc; Suresh, I.; Neetu, S.; Durand, F.; Shenoi, S.S.C.; Al Saafani, M.A.

    of interannual sea-level variability in the Indian Ocean D. Shankar a ,S.G.Aparna a ,J.P.McCreary b ,I.Suresh a , S. Neetu a ,F.Durand c , S. S. C. Shenoi a , M. A. Al Saafani a,d a National Institute of Oceanography,Dona Paula, Goa 403 004, India. b SOEST..., for example,the reviewby Schott and McCreary, 2001) implies that changes in sea level can be forced at a given loca- tion by winds blowing elsewhere earlier in the season. This phenomenon, called remote forcing, “merges the equatorial Indian Ocean, the Arabian...

  12. Optical closure of apparent optical properties in coastal waters off Goa

    Digital Repository Service at National Institute of Oceanography (India)

    Talaulikar, M.; Suresh, T.; Desa, E.S.; Inamdar, A.

    by manufacturer. The instrument was deployed in “fish out” mode positioning the boat such as to keep the radiometer well under the sun avoiding the boat shadow. Care was taken to deploy the radiometer with tilt less than 5 degrees (Suresh et al. 2012... analytical ocean color model for global-scale applications. Applied Optics, 41, 2705-2714 . Mobley, C. D. (1994). Light and water: radiative transfer in natural waters. Academic Press. Mobley, C. D., Gentili, B., Gordon, H. R., Jin, Z., Kattawar, G...

  13. Spirituality in business: Sparks from the Anvil

    Directory of Open Access Journals (Sweden)

    B. Mahadevan

    2013-06-01

    Full Text Available The economic crises in the recent past have led to a renewed interest in exploring the role of spirituality in business management. However there are several challenges in understanding what “spirituality” means in an operational sense of business management. This article first traces the research in the area of spirituality as applied to business and in the second part, reports on the beliefs of Suresh B. Hundre, Chairman and MD of Polyhydron Pvt. Ltd, Belgaum, India, as practised in Polyhydron, a company known for its ethical management, and where the concept of “Business Ashrama” integrates spirituality into business.

  14. Effect of residual stress on the nanoindentation response of (100) copper single crystal

    International Nuclear Information System (INIS)

    Zhu, Li-na; Xu, Bin-shi; Wang, Hai-dou; Wang, Cheng-biao

    2012-01-01

    Experimental measurements were used to investigate the effect of residual stress on the nanoindentation of (100) copper single crystal. Equi-biaxial tensile and compressive stresses were applied to the copper single crystal using a special designed apparatus. It was found that residual stresses greatly affected peak load, curvature of the loading curve, elastically recovered depth, residual depth, indentation work, pile-up amount and contact area. The Suresh and Giannakopoulos and Lee and Kwon methods were used to calculate the residual stresses from load-depth data and morphology observation of nanoindents using atomic force microscopy. Comparison of the obtained results with stress values from strain gage showed that the residual stresses analyzed from the Suresh and Giannakopoulos model agreed well with the applied stresses. -- Highlights: ► Residual stresses greatly affected various nanoindentation parameters. ► The contact area can be accurately measured from AFM observation. ► The residual stresses analyzed from the S and G model agreed well with applied stresses.

  15. Genes, Gender, Hormones, and Doping in Sport: A Convoluted Tale

    Directory of Open Access Journals (Sweden)

    Alan D. Rogol

    2017-10-01

    Full Text Available We are writing this piece in the aftermath of the 2016 Olympic Games in Rio de Janeiro, Brazil. Each of the words in the title plays a role(s in deciding who may compete, especially who may compete as a woman. We shall be careful to disentangle the issues of genes and gender from hormonal levels of the potent androgen testosterone, and very clearly demarcate these natural occurrences from those of doping, for which the World Anti-Doping Agency has established strict guidelines. These elements became conflated in the aftermath of the Court of Arbitration of Sport’s decision, now more than 2 years ago, concerning the teenage Indian sprinter, Dutee Chand. Although many people associate hyperandrogenism with doping and gender determination, each is different and has a distinct function.

  16. The influence of methane/argon plasma composition on the formation of the hydrogenated amorphous carbon films

    International Nuclear Information System (INIS)

    Chen, Hsin-Hung; Liao, Jiunn-Der; Weng, Chih-Chiang; Hsieh, Jui-Fu; Chang, Chia-Wei; Lin, Chao-Hsien; Cho, Ting-Pin

    2011-01-01

    The quality of the a-C:H films was particularly correlated with the mixed ratio of methane/argon plasma. For a constant supply of energy and flowing rate, the optical emission from H α intensity linearly increased with the addition of methane in argon plasma, while that from intensities of radiation of diatmoic radicals (CH*and C 2 *) exponentially decreased. For the a-C:H films, the added methane in argon plasma tended to raise the quantity of hydrogenated carbon or sp 3 C-H structure, which exponentially decreased the nano-hardness and friction coefficient of the films. In contrast, the electric resistance of the films enlarged dramatically with the increase of the methane content in argon plasma. It is therefore advantageous to balance the mechanical properties and electrical resistance of the a-C:H film by adjusting plasma composition in the course of the film-growing process.

  17. Customization of stock eye prosthesis for a pediatric patient by a simplified technique.

    Science.gov (United States)

    Jurel, Sunit Kumar; Talwar, Naina; Chand, Pooran; Singh, Raghuwar D; Gupta, Durga Shanker

    2012-05-01

    The unfortunate loss or absence of an eye may be caused by congenital defect , irreparable trauma, tumor or blind eye. The role of the maxillofacial prosthodontist in fabricating an ocular prosthesis to restore facial symmetry and normal appearance for the anophthalmic patient becomes essential. A custom-made ocular prosthesis is an excellent alternative for the people who lose their eye especially in young age. It has acceptable fit, retention and esthetics but is technically difficult to fabricate. On the other hand the stock eye has compromised fit and poor esthetics. Our case report presents a simple technique of customization of stock eye prosthesis to provide accurate fit and acceptable esthetics. How to cite this article: Jurel SK, Talwar N, Chand P, Singh RD, Gupta DS. Customization of Stock Eye Prosthesis for a Pediatric Patient by a Simplified Technique. Int J Clin Pediatr Dent 2012;5(2):155-158.

  18. Presentation: Twentieth-century Dictatorships and Religion

    Directory of Open Access Journals (Sweden)

    Jan Nelis

    2009-12-01

    Full Text Available Este dossier agrupa trabajos que cubren una amplia zona geográfica, ofreciendo diferentes puntos de vista sobre aspectos concernientes a la relación entre políticas dictatoriales y religión. El resultado final es ocho artículos que abordan la cuestión en cuatro continentes: Asia, África, América y Europa. Por la diversidad de enfoques, los artículos tratan, desde perspectivas diferentes, las actitudes “pragmáticas” coloniales y postcoloniales hacia la religión en África (Grandhomme y Kroubo Dagnini, la identidad religiosa africana (Chande, el uso de la religión como una fuente de moral y ética en Argentina (Cousins y Francia (Stevens, el punto de tensión entre la religión y política tradicionales y el mito en China (Lee e Italia (Nelis, y las actitudes de la dictadura hacia la identidad religiosa en España (Beck.____________________ABSTRACT:This dossier contains essays that cover a broad geographic area, offering different points of view on various aspects concerning the relation between dictatorship policies and religion. The final result are eight articles, which deal with the situation on four continents: Asia, Africa, America and Europe. Presenting a great variety of approaches, the articles show different views on the “pragmatic” colonial and post-colonial attitudes towards religion in Africa (Grandhomme and Kroubo Dagnini, African religious identity (Chande, the use of religion as a source of morals and ethics in Argentina (Cousins and France (Stevens, the point of tension between traditional religion and politics and the myth in China (Lee and Italy (Nelis and the dictatorship’s attitude towards the religious identity in Spain (Beck.

  19. Microbiological Study on Some Gamma Irradiated Personal Care Products

    International Nuclear Information System (INIS)

    Ahmed, M.A.Sh.A.

    2014-01-01

    Humans have a basic need to change their appearance. The vastness of today‟s cosmetics and toiletries industry clearly indicates this wide spread and basic need for personal care products. Perhaps this need arises because these products allow us to make ourselves unique for rituals or societal reasons. We apparently have a primal need for them for our well-being (Geis, 2006). This industry had achieved stupendous growth within a short span of time and is now a multi-billion dollar industry. It would continue to grow as long as people are ready to spend a fortune to look their best. The result of which is large number of brands and twice the number of hair and skin care products (Naz et al., 2012). The term ''personal care products''refers to a wide variety of items find in the health and beauty departments and the products commonly referred to as ''personal care products''are cosmetics (FDA, 2012 a and b). Makeup can do wonders for women, but it can be dangerous to their health, if not handled properly (Archer, 1998 and Persaud, 2008). Practically all cosmetics are subjected to contamination with microorganisms (Oliviera et al., 2013). Contamination leads to several types of infections that range in severity from mild to serious (Ashour et al., 1987). Microbial load of personal care product is affected by the level of contamination during manufacturing, after manufacturing and during consumer use (Razooki et al., 2010 and Muhammed, 2011). The quality of cosmetic products largely depends on the quality of starting materials. The guidelines of good manufacturing practice for cosmetic products (GMPC) have clearly depicted the necessity of the starting materials to comply with specifications (WHO, 1992). Cosmetic contamination awareness is even worse among the younger age. Many women even share makeup and applicators with friends and their family, increasing their chances of facial infection. Makeup can easily be contaminated by the repetitive use to the skin using

  20. High quality draft genome sequence and analysis of Pontibacter roseus type strain SRC-1T (DSM 17521T) isolated from muddy waters of a drainage system in Chandigarh, India

    Energy Technology Data Exchange (ETDEWEB)

    Mukherjee, Supratim; Lapidus, Alla; Shapiro, Nicole; Cheng, Jan-Fang; Han, James; Reddy, TBK; Huntemann, Marcel; Ivanova, Natalia; Mikhailova, Natalia; Chen, Amy; Palaniappan, Krishna; Spring, Stefan; Göker, Markus; Markowitz, Victor; Woyke, Tanja; Tindall, Brian J.; Klenk, Hans-Peter; Kyrpides, Nikos C.; Pati, Amrita

    2015-01-01

    Pontibacter roseus Suresh et al 2006 is a member of genus Pontibacter family Cytophagaceae, class Cytophagia. While the type species of the genus Pontibacter actiniarum was isolated in 2005 from a marine environment, subsequent species of the same genus have been found in different types of habitats ranging from seawater, sediment, desert soil, rhizosphere, contaminated sites, solar saltern and muddy water. Here we describe the features of Pontibacter roseus strain SRC-1T along with its complete genome sequence and annotation from a culture of DSM 17521T. The 4,581,480 bp long draft genome consists of 12 scaffolds with 4,003 protein-coding and 50 RNA genes and is a part of Genomic encyclopedia of Type Strains, Phase I: the one thousand microbial genomes (KMG-I) project.

  1. Smart Materials in Structural Health Monitoring, Control and Biomechanics

    CERN Document Server

    Soh, Chee-Kiong; Bhalla, Suresh

    2012-01-01

    "Smart Materials in Structural Health Monitoring, Control and Biomechanics" presents the latest developments in structural health monitoring, vibration control and biomechanics using smart materials. The book mainly focuses on piezoelectric, fibre optic and ionic polymer metal composite materials. It introduces concepts from the very basics and leads to advanced modelling (analytical/ numerical), practical aspects (including software/ hardware issues) and case studies spanning civil, mechanical and aerospace structures, including bridges, rocks and underground structures. This book is intended for practicing engineers, researchers from academic and R&D institutions and postgraduate students in the fields of smart materials and structures, structural health monitoring, vibration control and biomedical engineering. Professor Chee-Kiong Soh and Associate Professor Yaowen Yang both work at the School of Civil and Environmental Engineering, Nanyang Technological University, Singapore. Dr. Suresh Bhalla is an A...

  2. Extraglottic airway devices: technology update

    Directory of Open Access Journals (Sweden)

    Sharma B

    2017-08-01

    Full Text Available Bimla Sharma, Chand Sahai, Jayashree Sood Department of Anaesthesiology, Pain and Perioperative Medicine, Sir Ganga Ram Hospital, New Delhi, India Abstract: Extraglottic airway devices (EADs have revolutionized the field of airway management. The invention of the laryngeal mask airway was a game changer, and since then, there have been several innovations to improve the EADs in design, functionality, safety and construction material. These have ranged from changes in the shape of the mask, number of cuffs and material used, like rubber, polyvinylchloride and latex. Phthalates, which were added to the construction material in order to increase device flexibility, were later omitted when this chemical was found to have serious adverse reproductive outcomes. The various designs brought out by numerous companies manufacturing EADs resulted in the addition of several devices to the airway market. These airway devices were put to use, many of them with inadequate or no evidence base regarding their efficacy and safety. To reduce the possibility of compromising the safety of the patient, the Difficult Airway Society (DAS formed the Airway Device Evaluation Project Team (ADEPT to strengthen the evidence base for airway equipment and vet the new extraglottic devices. A preuse careful analysis of the design and structure may help in better understanding of the functionality of a particular device. In the meantime, the search for the ideal EAD continues. Keywords: extraglottic airway devices, laryngeal mask airway, other extraglottic airway devices, safety, technology update

  3. Comparison of the corneal biomechanical effects after small-incision lenticule extraction and Q value guided femtosecond laser-assisted laser in situ keratomileusis

    Directory of Open Access Journals (Sweden)

    Jun Zhang

    2016-04-01

    Full Text Available AIM:By comparing the changes of biomechanical properties of the cornea after small-incision lenticule extraction(SMILEand those after Q value guided femtosecond laser-assisted laser in situ keratomileusis(FSLASIK, to study the stability of biomechanical properties of the cornea after these two kinds of surgery and provide objective data for clinical operation.METHODS: Prospective comparative cases. One hundred and two cases(200 eyeswith myopia and myopic astigmatism were divided into 2 groups, 51 cases(100 eyesfor SMILE, and 51 cases(100 eyesfor Q value guided FS-LASIK. Corneal hysteresis(CHand the corneal resistance factor(CRFwere quantitatively assessed with the Ocular Response Analyzer(ORApreoperatively and 1d, 2wk, 1 and 3mo postoperatively.RESULTS: The decrease in CH and the CRF were statistically significant in both groups(PP>0.05. There were no statistically significant differences between the biomechanical changes in the two groups at any time(P>0.05.CONCLUSION: Both SMILE and Q value guided FS-LASIK can cause biomechanical decreases in the cornea. After 1d postoperatively, the decreases are nearly stable. There are no significant differences between the effect of SMILE and Q value guided FS-LASIK on the biomechanical properties of the cornea.

  4. Nicolas Lyon-Caen , La boîte à Perrette, le jansénisme parisien au xviiie siècle

    OpenAIRE

    Vermander, Benoît

    2012-01-01

    Nicolas Lyon-­­­Caen publie ici sa thèse sou­­te­­nue en 2008 à l’uni­­ver­­sité Paris I (dir. Cl. Mi­­­chaud) sous le titre Mar­­chands de miracles. La bour­­geoi­­sie jan­­sé­­niste pari­­sienne au xviiie siècle, elle-­­­même pro­­lon­­ge­­ment d’une thèse de l’École des Chartes consa­­crée au finan­­ce­­ment du « parti » jan­­sé­­niste au xviiie siècle (La boîte à Perrette, 2002). Ce n’est donc pas une his­­toire de l’ensemble des jan­­sé­­nistes pari­­siens que l’on trou­­vera dans cet ou...

  5. Evidências do Entendimento de Quatro Pronunciamentos Contábeis por Auditores Independentes do Brasil

    Directory of Open Access Journals (Sweden)

    Neirilaine Silva de Almeida

    2013-01-01

    Full Text Available The employment of an international standard for corporate financial statements worldwide has been increasingly required. However the concern some authors have as to effective comparability of information, depending on the possibility of disparate interpretations even with the use of identical standards, still persists. Thus, this study aims to identify how independent auditors of companies indexed in the CVM interpret four Brazilian Accounting Pronouncements, by means of a questionnaire adapted from Chand, Patel and Patel (2010. In addition, the research attempts to identify the association between the auditors’ interpretations and four variables (the size of the undertaking; familiarity with IFRS; experience with auditing; and experience with IFRS-related activities. Analysis was done via Chi-square Test, Correspondence Analysis (ANACOR and Homogeneity Analysis (HOMALS. The results show a lack of consensus among auditors in the sample. It was noticed that interpretations of the three Brazilian Accounting Pronouncements were statistically distinct in function: the size of the undertaking, familiarity with IFRS, and experience with IFRS-related activities. In light of these results, it can be inferred that, within the use of the same standard, there is a possibility that Brazilian professionals have different interpretations and, therefore, make decisions that will produce non-comparable accounting reports.

  6. Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications

    Directory of Open Access Journals (Sweden)

    Ranganathan R

    2012-02-01

    Full Text Available Ramya Ranganathan1,*, Shruthilaya Madanmohan1,*, Akila Kesavan1, Ganga Baskar1, Yoganathan Ramia Krishnamoorthy2, Roy Santosham3, D Ponraju4, Suresh Kumar Rayala2, Ganesh Venkatraman1 1Department of Human Genetics, Sri Ramachandra University, Porur, 2Department of Biotechnology, Indian Institute of Technology, Madras, 3Department of Radiology and Imaging Sciences, Sri Ramachandra University, Porur, Chennai, 4Safety Engineering Division, Nuclear and Engineering Safety Group, Indira Gandhi Center for Atomic Research, Kalpakkam, India*Authors contributed equally to this workAbstract: The focus on nanotechnology in cancer treatment and diagnosis has intensified due to the serious side effects caused by anticancer agents as a result of their cytotoxic actions on normal cells. This nonspecific action of chemotherapy has awakened a need for formulations capable of definitive targeting with enhanced tumor-killing. Nanooncology, the application of nanobiotechnology to the management of cancer, is currently the most important area of nanomedicine. Currently several nanomaterial-based drug-delivery systems are in vogue and several others are in various stages of development. Tumor-targeted drug-delivery systems are envisioned as magic bullets for cancer therapy and several groups are working globally for development of robust systems.Keywords: patient-friendly, drug-delivery systems, cancer, nanomedicine

  7. First report of MRI findings in a case of an autoamputated wandering calcified ovary

    Directory of Open Access Journals (Sweden)

    Mahajan PS

    2014-03-01

    Full Text Available Parag Suresh Mahajan, Nazeer Ahamad, Sheik Akbar Hussain Department of Radiology, Al-Khor Hospital, Hamad Medical Corporation, Doha, Qatar Abstract: An autoamputated wandering calcified ovary (AWCO is an extremely rare cause of abdominal calcification in the pediatric population. We present the magnetic resonance imaging (MRI features of AWCO in a child. To our knowledge, the MRI features of AWCO have not been previously described in the published literature. Our case report indicates that the MRI findings are characteristic in the diagnosis of an AWCO and can completely obviate the need for invasive procedures in this mostly benign disease. An AWCO should be considered in all cases of mobile calcific opacities on radiographs in female patients. We advise that MRI be conducted in all suspected cases of AWCO for accurate and noninvasive diagnosis, and regular follow-up should be performed with ultrasound. The findings in our case report have the potential to change the course of investigations and management in suspected cases. Keywords: magnetic resonance imaging, ovary, adnexa, autoamputation, wandering calcification

  8. Magnetic resonance imaging features of brain and spinal cord injury in a fatal case of isopropanol intoxication

    Directory of Open Access Journals (Sweden)

    Mahajan PS

    2014-03-01

    Full Text Available Parag Suresh Mahajan,1 Joyal Jacob Mathew,2 Abhilash Pulincherry Jayaram,1 Vidya Chander Negi,1 Mohamed Milad Abu Hmaira21Department of Radiology, 2Department of Medicine, Al-Khor Hospital, Hamad Medical Corporation, Doha, QatarAbstract: A 60-year-old man presented with headache, dizziness, and disorientation one day after consumption of isopropanol along with ethanol. Computed tomography (CT of the brain performed immediately was unremarkable. The patient collapsed within the hospital 30 minutes after the CT scan was done, and remained comatose until death, showing no improvement with symptomatic treatment. Magnetic resonance imaging of the brain and spine done 6 days after admission revealed bilaterally symmetrical hyperintensities involving the cerebral and cerebellar cortex and white matter, basal ganglia, thalami, and brainstem on T2-weighted, fluid attenuated inversion recovery and diffusion weighted images; similar hyperintensities were seen involving the swollen and edematous cervical spinal cord and cerebellar tonsillar herniation compressing the proximal cervical cord. Petechial hemorrhages were also noted within the brainstem. These features are compatible with toxic injury to the brain and cervical spinal cord. To our knowledge, the magnetic resonance imaging features of brain and spinal cord injury and cerebellar tonsillar herniation, secondary to isopropanol intoxication have not been reported in the published literature before.Keywords: alcohol intoxication, computed tomography, isopropyl alcohol, ethyl alcohol, toxicity

  9. Renal colic and childbirth pain: female experience versus male perception

    Directory of Open Access Journals (Sweden)

    Miah S

    2017-07-01

    Full Text Available Saiful Miah,1,2 Charlotte Gunner,3 Lucy Clayton,4 Suresh Venugopal,5 Nigel R Boucher,5 Bo Parys61Division of Surgery and Interventional Science, University College London, London, UK; 2Urology Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK; 3Urology Department, Raigmore Hospital, Inverness, UK; 4Psychiatry Department, Highbury Hospital, Nottingham, UK; 5Urology Department, Chesterfield Royal Infirmary, Chesterfield, UK; 6Urology Department, Rotherham General Hospital, Rotherham, UKIntroductionRenal colic is often described by patients as the worst pain ever experienced.1 Pain during childbirth is also similarly described.2 To date, no study has comparatively evaluated the pain of renal colic to that of childbirth in female patients who have experienced both. Furthermore, no such study has evaluated the perception that men with renal colic have with respect to the pain experienced during childbirth. Here we present our cross-sectional observational study to address these questions. The primary objectives of our study were to answer these questions and highlight the severity of renal colic which is not always faced and treated aggressively.  

  10. November 2012 Arizona thoracic society notes

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2012-11-01

    Full Text Available No abstract available. Article truncated at 150 words. A dinner meeting was held on Wednesday, 11/28/2012 at Scottsdale Shea beginning at 6:30 PM. There were 20 in attendance representing the pulmonary, critical care, sleep, infectious disease, pathology, and radiology communities. Dr. George Parides stated he was unable to find further information on treating patients begun on biologicals for RA who developed a + QuantiFERON. Four cases were presented: 1. Dr. Suresh Uppalapu, a pulmonary fellow at Good Samaritan/VA, presented a case of a 29 yo woman with a rash and a myriad of nonspecific complaints. She had recently been a contestant in a reality TV show. Just prior to admission she developed a neurologic complaints including incontinence. Her CXR was negative but CT of the chest showed scattered areas of ground glass opacities peripherally. A MRI of the brain revealed nonspecific abnormalities. CBC showed an elevated eosinophil count of 8%. Coccidioidomycosis antigen was negative. An LP was performed …

  11. New insights into the genetic basis of infertility

    Directory of Open Access Journals (Sweden)

    Venkatesh T

    2014-12-01

    Full Text Available Thejaswini Venkatesh,1 Padmanaban S Suresh,2 Rie Tsutsumi3 1Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences, Bangalore, 2Centre for Biomedical Research, VIT University, Vellore, India; 3University of Tokushima, Institute of Health Bioscience, Department of Public Health and Nutrition, Tokushima, Japan Abstract: Infertility is a disease of the reproductive system characterized by inability to achieve pregnancy after 12 or more months of regular unprotected sexual intercourse. A variety of factors, including ovulation defects, spermatogenic failure, parental age, obesity, and infections have been linked with infertility, in addition to specific karyotypes and genotypes. The study of genes associated with infertility in rodent models has expanded the field of translational genetics in identifying the underlying cause of human infertility problems. Many intriguing aspects of the molecular basis of infertility in humans remain poorly understood; however, application of genetic knowledge in this field looks promising. The growing literature on the genetics of human infertility disorders deserves attention and a critical concise summary is required. This paper provides information obtained from a systematic analysis of the literature related to current research into the genetics of infertility affecting both sexes. Keywords: infertility, genetics, polycystic ovary syndrome, premature ovarian failure, spermatogenic failure, cystic fibrosis

  12. The influence of punching process on residual stress and magnetic domain structure of non-oriented silicon steel

    International Nuclear Information System (INIS)

    Cao, Hongzhi; Hao, Linpo; Yi, Jingwen; Zhang, Xianglin; Luo, Zhonghan; Chen, Shenglin; Li, Rongfeng

    2016-01-01

    The main purpose of this paper is to investigate the influence of punching process on residual stress and magnetic domain structure. The residual stress in non-oriented silicon steel after punching process was measured by nanoindentation. The maximum depth was kept constant as 300 nm during nanoindentation. The material around indentation region exhibited no significant pile-up deformation. The calculation of residual stress was based on the Suresh theoretical model. Our experimental results show that residual compressive stress was generated around the sheared edge after punching. The width of residual stress affected zone by punching was around 0.4–0.5 mm. After annealing treatment, the residual stress was significantly decreased. Magnetic domain structure was observed according to the Bitter method. The un-annealed sample exhibited complicated domain patterns, and the widths of the magnetic domains varied between 3 µm and 8 µm. Most of the domain patterns of the annealed sample were 180°-domains and 90°-domains, and the widths of the domains decreased to 1–3 µm. - Highlights: • The residual stress distribution on sheared edge was measured. • The residual compressive stress was generated around the sheared edge. • The width of residual stress affected zone was about 0.4–0.5 mm. • The shape and width of the domain structure would be changed by annealing.

  13. On the controlling parameters for fatigue-crack threshold at low homologous temperatures

    International Nuclear Information System (INIS)

    Yu, W.; Gerberich, W.W.

    1983-01-01

    Fatigue crack propagation phenomena near the threshold stress intensity level ΔK /SUB TH/ , has been a vigorously studied topic in recent years. Near threshold the crack propagates rather slowly, thus giving enough time for various physical and chemical reactions to take place. Room air, which is the most commonly encountered environment, can still supply various ingredients such as oxygen, water vapor (and thus hydrogen) to support these reactions. Much effort had been directed toward the environmental aspects of near threshold fatigue crack growth. By conducting tests under vacuum, Suresh and coworkers found that the crack propagation rate in a 2-1/4 Cr-1Mo steel was higher in vacuum than in air. An oxide induced closure, which served to reduce the effective stress intensity at the crack tip, seems to furnish a good explanation. Neumann and coworkers proposed that during the fatigue process, extrusion-intrusion pairs can develop as a consequence of reversed slip around the crack tip when the crack was propagated near threshold stress intensity. Beevers demonstrated that fatigue fracture surfaces contact each other during unloading even under tension-tension cycling. Kanninen and Atkinson also reached the conclusion that the compressive stress acting at the crack tip due to residual plasticity can induce closure. Microstructural effects have also been cited as important factors in near threshold crack growth. It is generally accepted that coarser grains have a beneficial effect on the resistance to the near threshold crack propagation

  14. Molecular single-bond covalent radii for elements 1-118.

    Science.gov (United States)

    Pyykkö, Pekka; Atsumi, Michiko

    2009-01-01

    A self-consistent system of additive covalent radii, R(AB)=r(A) + r(B), is set up for the entire periodic table, Groups 1-18, Z=1-118. The primary bond lengths, R, are taken from experimental or theoretical data corresponding to chosen group valencies. All r(E) values are obtained from the same fit. Both E-E, E-H, and E-CH(3) data are incorporated for most elements, E. Many E-E' data inside the same group are included. For the late main groups, the system is close to that of Pauling. For other elements it is close to the methyl-based one of Suresh and Koga [J. Phys. Chem. A 2001, 105, 5940] and its predecessors. For the diatomic alkalis MM' and halides XX', separate fits give a very high accuracy. These primary data are then absorbed with the rest. The most notable exclusion are the transition-metal halides and chalcogenides which are regarded as partial multiple bonds. Other anomalies include H(2) and F(2). The standard deviation for the 410 included data points is 2.8 pm.

  15. Melioidosis in acute cholangitis of diabetic patient: a forgotten diagnosis

    Directory of Open Access Journals (Sweden)

    Mohamad N

    2012-08-01

    Full Text Available Nasir Mohamad,1 Suresh Ponnusamy,2 Sunita Devi,3 Rishya Manikam,4 Ilya Irinaz Idrus,1 Nor Hidayah Abu Bakar51Department of Emergency Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia; 2AIMST University, Bedong, Malaysia; 3Hospital Sultan Abdul Halim, Sungai Petani, Malaysia; 4University Malaya Medical Centre, Kuala Lumpur, Malaysia; 5Department of Pathology, Hospital Raja Perempuan Zainab II, Kota Bharu, MalaysiaAbstract: Melioidosis presents with a wide range of clinical presentations, which include severe community-acquired pneumonia, septicemia, central nervous system infection, and less severe soft tissue infection. Hence, its diagnosis depends heavily on the clinical microbiology laboratory for culture. In this case report, we describe an atypical presentation of melioidosis in a 52-year-old man who had fever, right upper-abdominal pain, and jaundice for 15 days. Melioidosis caused by Burkholderia pseudomallei was subsequently diagnosed from blood culture. As a primary care physician, high suspicion index is of great importance. High suspicion index of melioidosis in a high-risk group patient, such as the patient with diabetes mellitus and diabetic foot, is crucial in view of atypical presentations of pseudomonas sepsis. A correct combination of antibiotic administration in the early phase of therapy will determine its successful outcome.Keywords: Burkholderia pseudomallei, atypical, high suspicion, primary care

  16. How do A-train Sensors Inter-Compare in the Retrieval of Above-Cloud Aerosol Optical Depth? A Case Study based Assessment

    Science.gov (United States)

    Jethva, H. T.; Torres, O.; Waquet, F.; Chand, D.

    2013-12-01

    Atmospheric aerosols are known to produce a net cooling effect in the cloud-free conditions. However, when present over the reflective cloud decks, absorbing aerosols such as biomass burning generated smoke and wind-blown dust can potentially exert a large positive forcing through enhanced atmospheric heating resulting from cloud-aerosol radiative interactions. The interest on this aspect of aerosol science has grown significantly in the recent years. Particularly, development of the satellite-based retrieval techniques and unprecedented knowledge on the above-cloud aerosol optical depth (ACAOD) is of great relevance. A direct validation of satellite ACAOD is a difficult task primarily due to lack of ample in situ and/or remote sensing measurements of aerosols above cloud. In these circumstances, a comparative analysis on the inter-satellite ACAOD retrievals can be performed for the sack of consistency check. Here, we inter-compare the ACAOD of biomass burning plumes observed from different A-train sensors, i.e., MODIS [Jethva et al., 2013], CALIOP [Chand et al., 2008], POLDER [Waquet et al., 2009], and OMI [Torres et al., 2012]. These sensors have been shown to acquire sensitivity and independent capabilities to detect and retrieve aerosol loading above marine stratocumulus clouds--a kind of situation often found over the southeastern Atlantic Ocean during dry burning season. A systematic one-to-one comparison reveals that, in general, all passive sensors and CALIOP-based research methods retrieve comparable ACAOD over homogeneous cloud fields. The high-resolution sensors (MODIS and CALIOP) are able to retrieve aerosols over thin clouds but with larger discrepancies. Given the different types of sensor measurements processed with different algorithms, a reasonable agreement between them is encouraging. A direct validation of satellite-based ACAOD remains an open challenge for which dedicated field measurements over the region of frequent aerosol/cloud overlap are

  17. The SPARDIG project - Transforming analogue sparker records from the Norwegian continental shelf into SEG-Y format, first results

    Science.gov (United States)

    Schaming, Marc; Rise, Leif; Chand, Shyam; Reidulv, Bøe; Terje Osmundsen, Per; Redfield, Tim

    2017-04-01

    A large number of sparker lines were acquired on the Norwegian continental shelf during the years 1970-1982, by IKU (Sintef Petroleum Research). The responsibility of the analogue seismic database was transferred to NGU in 1998; this included storage of the physical data (original paper rolls and half-scale film copies) and the digital navigation database. The data (from 60°N to 71°30N) were in the early eighties subdivided in 6 data packages, and offered for sale to oil companies as half scale folded paper copies (25 cm width). Navigation applied was mainly Decca Main Chain. The 2014-2016 SPARDIG project (Chand et al., 2016) was supported by NGU, AkerBP (Det Norske), Lundin Norway and the Seabed Project. In the project, IPGS has transformed 374 rolls of analogue sparker lines in 17 different surveys into SEG-Y format. The total length of converted survey lines is 31 261 kilometers. Rolls were scanned at 600 dpi and converted into SEG-Y using the SeisTrans (Caldera software) application (Miles et al., 2007). SeisTrans uses interactive, iterative and repeatable steps in a dedicated graphics window. A first step allows definition of axes and scales, then record time lines (horizontal TWT times and navigation time lines down the record) are picked and removed, and traces are defined. At this step, control tools are available to ensure the quality of the traces. After that, navigation information extracted and interpolated from excel files are added to trace headers. A continuous QC process allows production of SEG-Y files directly readable by interpretation software. The SEG-Y data will be delivered to the Norwegian Discos National Repository (https://portal.diskos.cgg.com/whereoil-data/) but access will be restricted to participants until 1st April 2019. IKU sparker lines have higher resolution than conventional 2D lines, but the penetration is limited. The data sets are complementary to each other. In 2D seismic lines, it is often difficult to delineate units in

  18. Development of Advanced Ceramic Manufacturing Technology; FINAL

    International Nuclear Information System (INIS)

    Pujari, V.K.

    2001-01-01

    Advanced structural ceramics are enabling materials for new transportation engine systems that have the potential for significantly reducing energy consumption and pollution in automobiles and heavy vehicles. Ceramic component reliability and performance have been demonstrated in previous U.S. DOE initiatives, but high manufacturing cost was recognized as a major barrier to commercialization. Norton Advanced Ceramics (NAC), a division of Saint-Gobain Industrial Ceramics, Inc. (SGIC), was selected to perform a major Advanced Ceramics Manufacturing Technology (ACMT) Program. The overall objectives of NAC's program were to design, develop, and demonstrate advanced manufacturing technology for the production of ceramic exhaust valves for diesel engines. The specific objectives were (1) to reduce the manufacturing cost by an order of magnitude, (2) to develop and demonstrate process capability and reproducibility, and (3) to validate ceramic valve performance, durability, and reliability. I n order to achieve these objectives, NAC, a leading U.S. advanced ceramics component manufacturer, assembled a multidisciplinary, vertically integrated team. This team included: a major diesel engine builder, Detroit Diesel Corporation (DDC); a corporate ceramics research division, SGIC's Northboro R and D Center; intelligent processing system developers, BDM Federal/MATSYS; a furnace equipment company, Centorr/Vacuum Industries; a sintering expert, Wittmer Consultants; a production OEM, Deco-Grand; a wheel manufacturer and grinding operation developer, Norton Company's Higgins Grinding Technology Center (HGTC); a ceramic machine shop, Chand Kare Technical Ceramics; and a manufacturing cost consultant, IBIS Associates. The program was divided into four major tasks: Component Design and Specification, Component Manufacturing Technology Development, Inspection and Testing, and Process Demonstration

  19. Dysrhythmias in Laypersons During Centrifuge-Simulated Suborbital Spaceflight.

    Science.gov (United States)

    Suresh, Rahul; Blue, Rebecca S; Mathers, Charles H; Castleberry, Tarah L; Vanderploeg, James M

    2017-11-01

    There are limited data on cardiac dysrhythmias in laypersons during hypergravity exposure. We report layperson electrocardiograph (ECG) findings and tolerance of dysrhythmias during centrifuge-simulated suborbital spaceflight. Volunteers participated in varied-length centrifuge training programs of 2-7 centrifuge runs over 0.5-2 d, culminating in two simulated suborbital spaceflights of combined +Gz and +Gx (peak +4.0 Gz, +6.0 Gx, duration 5 s). Monitors recorded pre- and post-run mean arterial blood pressure (MAP), 6-s average heart rate (HR) collected at prespecified points during exposures, documented dysrhythmias observed on continuous 3-lead ECG, self-reported symptoms, and objective signs of intolerance on real-time video monitoring. Participating in the study were 148 subjects (43 women). Documented dysrhythmias included sinus pause (N = 5), couplet premature ventricular contractions (N = 4), bigeminy (N = 3), accelerated idioventricular rhythm (N = 1), and relative bradycardia (RB, defined as a transient HR drop of >20 bpm; N = 63). None were associated with subjective symptoms or objective signs of acceleration intolerance. Episodes of RB occurred only during +Gx exposures. Subjects had a higher post-run vs. pre-run MAP after all exposures, but demonstrated no difference in pre- and post-run HR. RB was more common in men, younger individuals, and subjects experiencing more centrifuge runs. Dysrhythmias in laypersons undergoing simulated suborbital spaceflight were well tolerated, though RB was frequently noted during short-duration +Gx exposure. No subjects demonstrated associated symptoms or objective hemodynamic sequelae from these events. Even so, heightened caution remains warranted when monitoring dysrhythmias in laypersons with significant cardiopulmonary disease or taking medications that modulate cardiac conduction.Suresh R, Blue RS, Mathers CH, Castleberry TL, Vanderploeg JM. Dysrhythmias in laypersons during centrifuge-stimulated suborbital

  20. Sustained Accelerated Idioventricular Rhythm in a Centrifuge-Simulated Suborbital Spaceflight.

    Science.gov (United States)

    Suresh, Rahul; Blue, Rebecca S; Mathers, Charles; Castleberry, Tarah L; Vanderploeg, James M

    2017-08-01

    Hypergravitational exposures during human centrifugation are known to provoke dysrhythmias, including sinus dysrhythmias/tachycardias, premature atrial/ventricular contractions, and even atrial fibrillations or flutter patterns. However, events are generally short-lived and resolve rapidly after cessation of acceleration. This case report describes a prolonged ectopic ventricular rhythm in response to high G exposure. A previously healthy 30-yr-old man voluntarily participated in centrifuge trials as a part of a larger study, experiencing a total of 7 centrifuge runs over 48 h. Day 1 consisted of two +Gz runs (peak +3.5 Gz, run 2) and two +Gx runs (peak +6.0 Gx, run 4). Day 2 consisted of three runs approximating suborbital spaceflight profiles (combined +Gx and +Gz). Hemodynamic data collected included blood pressure, heart rate, and continuous three-lead electrocardiogram. Following the final acceleration exposure of the last Day 2 run (peak +4.5 Gx and +4.0 Gz combined, resultant +6.0 G), during a period of idle resting centrifuge activity (resultant vector +1.4 G), the subject demonstrated a marked change in his three-lead electrocardiogram from normal sinus rhythm to a wide-complex ectopic ventricular rhythm at a rate of 91-95 bpm, consistent with an accelerated idioventricular rhythm (AIVR). This rhythm was sustained for 2 m, 24 s before reversion to normal sinus. The subject reported no adverse symptoms during this time. While prolonged, the dysrhythmia was asymptomatic and self-limited. AIVR is likely a physiological response to acceleration and can be managed conservatively. Vigilance is needed to ensure that AIVR is correctly distinguished from other, malignant rhythms to avoid inappropriate treatment and negative operational impacts.Suresh R, Blue RS, Mathers C, Castleberry TL, Vanderploeg JM. Sustained accelerated idioventricular rhythm in a centrifuge-simulated suborbital spaceflight. Aerosp Med Hum Perform. 2017; 88(8):789-793.

  1. Entropy-limited hydrodynamics: a novel approach to relativistic hydrodynamics

    Science.gov (United States)

    Guercilena, Federico; Radice, David; Rezzolla, Luciano

    2017-07-01

    We present entropy-limited hydrodynamics (ELH): a new approach for the computation of numerical fluxes arising in the discretization of hyperbolic equations in conservation form. ELH is based on the hybridisation of an unfiltered high-order scheme with the first-order Lax-Friedrichs method. The activation of the low-order part of the scheme is driven by a measure of the locally generated entropy inspired by the artificial-viscosity method proposed by Guermond et al. (J. Comput. Phys. 230(11):4248-4267, 2011, doi: 10.1016/j.jcp.2010.11.043). Here, we present ELH in the context of high-order finite-differencing methods and of the equations of general-relativistic hydrodynamics. We study the performance of ELH in a series of classical astrophysical tests in general relativity involving isolated, rotating and nonrotating neutron stars, and including a case of gravitational collapse to black hole. We present a detailed comparison of ELH with the fifth-order monotonicity preserving method MP5 (Suresh and Huynh in J. Comput. Phys. 136(1):83-99, 1997, doi: 10.1006/jcph.1997.5745), one of the most common high-order schemes currently employed in numerical-relativity simulations. We find that ELH achieves comparable and, in many of the cases studied here, better accuracy than more traditional methods at a fraction of the computational cost (up to {˜}50% speedup). Given its accuracy and its simplicity of implementation, ELH is a promising framework for the development of new special- and general-relativistic hydrodynamics codes well adapted for massively parallel supercomputers.

  2. Laparoscopic esophageal myotomy versus pneumatic dilation in the treatment of idiopathic achalasia: a meta-analysis of randomized controlled trials

    Directory of Open Access Journals (Sweden)

    Baniya R

    2017-09-01

    Full Text Available Ramkaji Baniya, Sunil Upadhaya, Jahangir Khan, Suresh Kumar Subedi, Tabrez Shaik Mohammed, Balvant K Ganatra, Ghassan Bachuwa Department of Internal Medicine, Hurley Medical Center, Michigan State University, Flint, MI, USA Background: Achalasia is a primary esophageal motility disorder of unknown etiology associated with abnormalities in peristalsis and lower esophageal sphincter relaxation. The disease is incurable; however, definitive treatment procedures like pneumatic dilation (PD/balloon dilation and laparoscopic esophageal myotomy (LEM are performed to relieve dysphagia and related symptoms. Currently, there is paucity of data comparing the outcomes of these procedures. The aim of this meta-analysis is to compare the short- and long-term success rates of PD and LEM. Methods: A thorough systematic search of PubMed, Scopus, clinicaltrials.gov, and Cochrane library was conducted for randomized controlled trials (RCTs comparing the outcomes of PD versus LEM in the treatment of achalasia. The Mantel-Haenszel method and random effect model were used to analyze the data. RCTs with outcome data at 3-month, 1-year, and 5-year intervals were analyzed. Results: A total of 437,378 and 254 patients at 3-month, 1-year, and 5-year intervals were analyzed for outcome data. At 3 months and 1 year, PD was not as effective as LEM (odds ratio [OR]: 0.50; confidence interval [CI] 0.31–0.82; P = 0.009 and OR: 0.47; CI 0.22–0.99; P = 0.21 but at 5 years, one procedure was non-inferior to the other (OR: 0.62; 0.33–1.19; P = 0.34. Conclusion: PD was as effective as LEM in relieving symptoms of achalasia in the long-term. Keywords: achalasia, balloon dilation, pneumatic dilation, laparoscopic myotomy, Heller’s myotomy

  3. Serological IgG avidity test for ocular toxoplasmosis

    Directory of Open Access Journals (Sweden)

    Suresh S

    2012-01-01

    Full Text Available Subramaniam Suresh1, Saidin Nor-Masniwati1, Muhd Nor Nor-Idahriani1, Wan-Hitam Wan-Hazabbah1, Mohamed Zeehaida2, Embong Zunaina11Department of Ophthalmology, 2Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, MalaysiaBackground: The purpose of this study was to evaluate the immunoglobulin (Ig G avidity of serological toxoplasmosis testing in patients with ocular inflammation and to determine the clinical manifestations of ocular toxoplasmosis.Methods: A retrospective review of all patients presenting with ocular inflammation to the Hospital Universiti Sains Malaysia, Kelantan, Malaysia between 2005 and 2009 was undertaken. Visual acuity, clinical manifestations at presentation, toxoplasmosis antibody testing, and treatment records were analyzed.Results: A total of 130 patients with ocular inflammation were reviewed retrospectively. The patients had a mean age of 38.41 (standard deviation 19.24, range 6–83 years. Seventy-one patients (54.6% were found to be seropositive, of whom five (3.8% were both IgG and IgM positive (suggestive of recently acquired ocular toxoplasmosis while one (0.8% showed IgG avidity ≤40% (suggestive of recently acquired ocular toxoplasmosis and 65 patients (50.0% showed IgG avidity >40% (suggestive of reactivation of toxoplasmosis infection. Chorioretinal scarring as an ocular manifestation was significantly more common in patients with seropositive toxoplasmosis (P = 0.036. Eighteen patients (13.8% were diagnosed as having recent and/or active ocular toxoplasmosis based on clinical manifestations and serological testing.Conclusion: Ocular toxoplasmosis is a clinical diagnosis, but specific toxoplasmosis antibody testing helps to support the diagnosis and to differentiate between reactivation of infection and recently acquired ocular toxoplasmosis.Keywords: ocular toxoplasmosis, chorioretinal scar, toxoplasmosis antibody, IgG avidity test

  4. BOMBAY: Instrumentation school

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Full text: Promising students had a foretaste of the latest laboratory techniques at the ICFA 1993 India School on Instrumentation in High Energy Physics held from February 15-26 and hosted by the Tata Institute of Fundamental Research (TIFR), Bombay. The scientific programme was put together by the ICFA Panel for Future Instrumentation, Innovation and Development, chaired by Tord Ekelof (Uppsala). The programme included lectures and topical seminars covering a wide range of detector subjects. In small groups, students got acquainted with modern detector technologies in the laboratory sessions, using experimental setups assembled in various institutes world-wide and shipped to Bombay for the School. The techniques covered included multiwire proportional chambers for detection of particles and photons, gaseous detectors for UV photons and X-ray imaging, the study of charge drift in silicon detectors, measurement of the muon lifetime using liquid scintillators, tracking using scintillating fibres, and electronics for sensitive detectors. The India School was attended by around 80 students from 20 countries; 34 came from Indian universities. It was the fifth in this series, previous Schools having been at Trieste (1987, 1989 and 1991) organized by the ICFA Panel and hosted and sponsored by the International Centre for Theoretical Physics, and in 1990, organized at Rio de Janeiro in collaboration with the Centro Brasileiro de Pesquisas Fisicas. The School was jointly directed by Suresh Tonwar (TIFR), Fabio Sauli (CERN) and Marleigh Sheaff (University of Wisconsin), and sponsored by TIFR and DAE (India), CERN (Switzerland), ICTP and INFN (Italy), British Council and RAL (UK), NSF and DOE (USA), KEK (Japan), IPP (Canada) and DESY (Germany)

  5. Potential role of coenzyme Q10 in health and disease conditions

    Directory of Open Access Journals (Sweden)

    Rodick TC

    2018-02-01

    Full Text Available Taylor C Rodick,1 Donna R Seibels,2 Jeganathan Ramesh Babu,1 Kevin W Huggins,1 Guang Ren,3 Suresh T Mathews2 1Department of Nutrition, Dietetics, & Hospitality Management, Auburn University, Auburn, 2Department of Nutrition and Dietetics, Samford University, 3Medicine-Endocrinology, Diabetes & Metabolism, University of Alabama at Birmingham, Birmingham, AL, USA Abstract: Coenzyme Q10 (CoQ10, an endogenously produced compound, is found in all human cells. Within the mitochondria, it plays a substantial role in energy production by acting as a mobile electron carrier in the electron transport chain. Outside the mitochondria, it acts as an excellent antioxidant by sequestering free radicals and working synergistically with other antioxidants, including vitamin E. Dietary contribution is limited, making endogenous production the primary source for optimal function. Now widely available as an over-the-counter supplement, CoQ10 has gained attention for its possible therapeutic use in minimizing the outcomes of certain metabolic diseases, notably cardiovascular disease, diabetes, neurodegenerative disease, and cancer. Research has shown positive results in subjects supplemented with CoQ10, especially in relation to upregulating antioxidant capability. Emerging research suggests beneficial effects of CoQ10 supplementation in individuals on statin medications. CoQ10 supplementation in individuals participating in strenuous exercise seems to exert some beneficial effects, although the data are conflicting with other types of physical activity. This broad review of current CoQ10 literature, while outlining its physiological/functional significance in health and disease conditions, also offers a dietitian’s perspective on its potential use as a supplement in the promotion of health and management of disease conditions. Keywords: coenzyme Q, antioxidant, oxidative stress, dietary supplement, statin

  6. Synthesis of PLGA nanoparticles of tea polyphenols and their strong in vivo protective effect against chemically induced DNA damage

    Directory of Open Access Journals (Sweden)

    Srivastava AK

    2013-04-01

    Full Text Available Amit Kumar Srivastava,1 Priyanka Bhatnagar,2 Madhulika Singh,1 Sanjay Mishra,1 Pradeep Kumar,2 Yogeshwer Shukla,1 Kailash Chand Gupta1,2 1Proteomics Laboratory, Indian Institute of Toxicology Research (CSIR, Lucknow, India; 2Nucleic Acid Research Laboratory, Institute of Genomics and Integrative Biology (CSIR, Delhi University Campus, India Abstract: In spite of proficient results of several phytochemicals in preclinical settings, the conversion rate from bench to bedside is not very encouraging. Many reasons are attributed to this limited success, including inefficient systemic delivery and bioavailability under in vivo conditions. To achieve improved efficacy, polyphenolic constituents of black (theaflavin [TF] and green (epigallocatechin-3-gallate [EGCG] tea in poly(lactide-co-glycolide nanoparticles (PLGA-NPs were entrapped with entrapment efficacy of ~18% and 26%, respectively. Further, their preventive potential against 7,12-dimethylbenzanthracene (DMBA-induced DNA damage in mouse skin using DNA alkaline unwinding assay was evaluated. Pretreatment (topically of mouse skin with either TF or EGCG (100 µg/mouse doses exhibits protection of 45.34% and 28.32%, respectively, against DMBA-induced DNA damage. However, pretreatment with TF-loaded PLGA-NPs protects against DNA damage 64.41% by 1/20th dose of bulk, 71.79% by 1/10th dose of bulk, and 72.46% by 1/5th dose of bulk. Similarly, 51.28% (1/20th of bulk, 57.63% (1/10th of bulk, and 63.14% (1/5th of bulk prevention was noted using EGCG-loaded PLGA-NP doses. These results showed that tea polyphenol-loaded PLGA-NPs have ~30-fold dose-advantage than bulk TF or EGCG doses. Additionally, TF- or EGCG-loaded PLGA-NPs showed significant potential for induction of DNA repair genes (XRCC1, XRCC3, and ERCC3 and suppression of DNA damage responsive genes (p53, p21, MDM2, GADD45α, and COX-2 as compared with respective bulk TF or EGCG doses. Taken together, TF- or EGCG-loaded PLGA-NPs showed a superior

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2002-07-01

    . x + 406 pp. -Jerome Teelucksingh, O. Nigel Bolland, The politics of labour in the British Caribbean: The social origins of authoritarianism and democracy in the labour movement. Kingston: Ian Randle; Princeton NJ: Marcus Weiner, 2001. xxii + 720 pp. -Jay R. Mandle, Randolph B. Persaud, Counter-Hegemony and foreign policy: The dialectics of marginalized and global forces in Jamaica. Albany: State University of New York Press, 2001. xviii + 248 pp. -Patrick Bellegarde-Smith, Mary A. Renda, Taking Haiti: Military occupation and the culture of U.S. imperialism, 1915-1940. Chapel Hill: University of North Carolina Press, 2001. xvi + 414 pp. -James W. St. G. Walker, Maureen G. Elgersman, Unyielding spirits: Black women and slavery in early Canada and Jamaica. New York: Garland, 1999. xvii + 188 pp. -Madhavi Kale, David Hollett, Passage from India to El Dorado: Guyana and the great migration. Madison NJ: Fairleigh Dickinson University Press, 1999. 325 pp. -Karen S. Dhanda, Linda Peake ,Gender, ethnicity and place: Women and identities in Guyana. London: Routledge, 1999. xii + 228 pp., D. Alissa Trotz (eds -Karen S. Dhanda, Moses Nagamootoo, Hendree's cure: Scenes from Madrasi life in a new world. Leeds, UK: Peepal Tree, 2000. 149 pp. -Stephen D. Glazier, Hemchand Gossai ,Religion, culture, and tradition in the Caribbean., Nathaniel Samuel Murrell (eds -Michiel van Kempen, A. James Arnold, A history of literature in the Caribbean. Volume 2: English- and Dutch- speaking regions. (Vera M. Kuzinski & Ineke Phaf-Rheinberger, sub-eds..Amsterdam/Philadelphia: John Benjamins, 2001. ix + 672 pp. -Frank Birbalsingh, Bruce King, Derek Walcott: A Caribbean life. New York: Oxford University Press, 2000. ix + 714 pp. -Frank Birbalsingh, Paula Burnett, Derek Walcott: Politics and poetics. Gainesville: University Press of Florida, 2001. xiii + 380 pp. -Jeanne Garane, Micheline Rice-Maximin, Karukéra: Présence littéraire de la Guadeloupe. New York: Peter Lang, 1998. x + 197 pp. -Jeanne

  8. What factors influence UK medical students’ choice of foundation school?

    Directory of Open Access Journals (Sweden)

    Miah S

    2017-04-01

    Full Text Available Saiful Miah,1,2 Karl H Pang,3 Wayne Rebello,4 Zoe Rubakumar,4 Victoria Fung,5 Suresh Venugopal,6 Hena Begum4 1Division of Surgery and Interventional science, University College London, London, UK; 2Department of Urology, Charing Cross Hospital Imperial College Healthcare NHS Trust, London, UK; 3Academic Urology Unit, University of Sheffield, Sheffield, UK; 4Medical School, University of Sheffield, Sheffield, UK; 5Department of Plastic Surgery, Royal Hallamshire Hospital, Sheffield, UK; 6Department of Urology, Chesterfield Royal Infirmary, Chesterfield, UK Background: We aimed to identify the factors influencing UK medical student applicants’ choice of foundation school. We also explored the factors that doctors currently approaching the end of their 2-year program believe should be considered. Methods: A cross-sectional study was conducted during the 2013–2014 academic year. An online questionnaire was distributed to 2092 final-year medical students from nine UK medical schools and 84 foundation year-2 (FY2 doctors from eight foundation schools. Participants were asked to rank their top 3 from a list of 12 factors that could potentially influence choice of foundation school on a 5-point Likert scale. Collated categorical data from the two groups were compared using a chi-square test with Yates correction. Results: Geographic location was overwhelmingly the most important factor for medical students and FY2 doctors with 97.2% and 98.8% in agreement, respectively. Social relationships played a pivotal role for medical student applicants. Clinical specialties within the rotations were of less importance to medical students, in comparison to location and social relationships. In contrast, FY2 doctors placed a significantly greater importance on the specialties undertaken in their 2-year training program, when compared to medical students (chi-square; p=0.0001. Conclusion: UK medical schools should make their foundation program applicants aware

  9. A Conceptual Framework to Enhance the Interoperability of Observatories among Countries, Continents and the World

    Science.gov (United States)

    Loescher, H.; Fundamental Instrument Unit

    2013-05-01

    Ecological research addresses challenges relating to the dynamics of the planet, such as changes in climate, biodiversity, ecosystem functioning and services, carbon and energy cycles, natural and human-induced hazards, and adaptation and mitigation strategies that involve many science and engineering disciplines and cross national boundaries. Because of the global nature of these challenges, greater international collaboration is required for knowledge sharing and technology deployment to advance earth science investigations and enhance societal benefits. For example, the Working Group on Biodiversity Preservation and Ecosystem Services (PCAST 2011) noted the scale and complexity of the physical and human resources needed to address these challenges. Many of the most pressing ecological research questions require global-scale data and global scale solutions (Suresh 2012), e.g., interdisciplinary data access from data centers managing ecological resources and hazards, drought, heat islands, carbon cycle, or data used to forecast the rate of spread of invasive species or zoonotic diseases. Variability and change at one location or in one region may well result from the superposition of global processes coupled together with regional and local modes of variability. For example, we know the El Niño-Southern Oscillation large-scale modes of variability in the coupled terrestrial-aquatic-atmospheric systems' correlation with variability in regional rainfall and ecosystem functions. It is therefore a high priority of government and non-government organizations to develop the necessary large scale, world-class research infrastructures for environmental research—and the framework by which these data can be shared, discovered, and utilized by a broad user community of scientists and policymakers, alike. Given that there are many, albeit nascent, efforts to build new environmental observatories/networks globally (e.g., EU-ICOS, EU-Lifewatch, AU-TERN, China-CERN, GEOSS

  10. Practical Field Survey Approach with Handle Device for Lead Contamination Assessment in Kabwe, Zambia

    Science.gov (United States)

    Nakamura, S.; Hirose, K.; Takeda, T.; Uchida, Y.; Nakata, H.; Nakayama, S.; Ishizuka, M.; Yabe, J.; Ito, M.; Igarashi, T.

    2017-12-01

    International joint research project for assessing lead soil contamination in Kabwe, Zambia was started by Zambian and Japanese scientists in 2008. Various scientific data and results have been obtained up to now. Data sharing among researchers and government officials is necessary for understanding current situation of lead contamination in Kabwe comprehensively. As lead contamination affects on local communities seriously, local community participation is important to solve the environmental issue in near future. This study, therefore, aims to develop GIS Data Integration System (GDIS as followed) consisted of GIS Data Sharing System (GDSS as followed) as web-GIS, FIELDNAUT as Android App for field survey and opensource SNS instance named Mastodon. GDIS will provide local communities to participate easily and support researchers to collect and understand about everyday situation and visualize lead contamination status in Kabwe, Zambia. GDIS is developed with opensource programs. GDSS was simply designed and developed on one desktop PC (Hirose et al., 2015) although common web-GIS requires many servers (Suresh et al., 2015). FIELDNAUT was developed in 2016. FIELDNAUT provides researchers plotting their locations on satellite images and thematic maps, filming and texting with their locations, and compiling and sharing data through GDSS. Mastodon will be used as a new FIELDNAUT communication function between local communities and researchers. It is an independent SNS instance, and the closed and secure communication system will be able to be developed. With this function, local communities will share photos and texts about their daily lives and situation around Kabwe by FIELDNAUT, and those data will be collected into GDSS. Researchers provide their results as hazard maps to local communities through FIELDNAUT. GDIS consisted of GDSS, FIELDNAUT and Mastodon encourages local community participation and let local communities be interested in their environmental issues

  11. Current perspectives on neonatal hypoglycemia, its management, and cerebral injury risk

    Directory of Open Access Journals (Sweden)

    Chandran S

    2015-02-01

    Full Text Available Suresh Chandran,1–4 Victor Samuel Rajadurai,1–3 Abdul Alim Abdul Haium,1–3 Khalid Hussain5,6 1Department of Neonatology, KK Women’s and Children’s Hospital, Singapore; 2Duke-NUS Graduate School of Medicine, Singapore; 3Yong Loo Lin School of Medicine, National University of Singapore, Singapore; 4Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 5Department of Paediatric Endocrinology, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, 6The Institute of Child Health, University College London, London, UK Abstract: Glucose is an essential substrate for mammalian cells; in particular, the brain needs glucose continuously as a primary source of energy. Hypoglycemia is the most common biochemical finding in the neonatal period. However, despite the common occurrence, there is still controversy on the definition of hypoglycemia in the newborn period. This has led to the development of guidelines designed to identify infants “at-risk” and the implementation of an “operational threshold” for physicians to consider intervention. In healthy term infants, the optimal hormonal and metabolic adaptations during the immediate neonatal period ensure an adequate energy substrate for the vital organs, whereas the abnormal glucose homeostasis observed in preterm and growth-retarded infants is multifactorial in origin. For these high-risk infants, it is important to identify, screen, and prevent significant hypoglycemia. Detailed investigations are warranted in infants with severe and persistent hypoglycemia. Neonatal hypoglycemia is a major cause of brain injury. The speculated mechanisms of cellular injury include excitatory neurotoxins active at N-methyl-D-aspartate receptors, increased mitochondrial free radical generation with initiation of apoptosis and altered cerebral energetic characteristics. This hypoglycemic brain injury predominantly affects parieto-occipital regions causing

  12. Characterizing sexual function in patients with generalized anxiety disorder: a pooled analysis of three vilazodone studies

    Directory of Open Access Journals (Sweden)

    Clayton AH

    2016-06-01

    Full Text Available Anita H Clayton,1 Suresh Durgam,2 Xiongwen Tang,2 Changzheng Chen,2 Adam Ruth,3 Carl Gommoll2 1Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, 2Forest Research Institute, Jersey City, NJ, 3Prescott Medical Communications Group, Chicago, IL, USA Background: Vilazodone has been shown to reduce core symptoms of generalized anxiety disorder (GAD in three randomized, double-blind, placebo-controlled trials. Since sexual dysfunction (SD is not well characterized in GAD, a post hoc analysis of these trials was conducted to evaluate the effects of vilazodone on sexual functioning in GAD patients. Materials and methods: Data were pooled from one fixed-dose trial of vilazodone 20 and 40 mg/day (NCT01629966 and two flexible-dose studies of vilazodone 20–40 mg/day (NCT01766401, NCT01844115 in adults with GAD. Sexual functioning was assessed using the Changes in Sexual Functioning Questionnaire (CSFQ. Outcomes included mean change from baseline to end of treatment (EOT in CSFQ total score and percentage of patients shifting from SD at baseline (CSFQ total score ≤47 for males, ≤41 for females to normal functioning at EOT. Treatment-emergent adverse events related to sexual functioning were also analyzed. Results: A total of 1,373 patients were included in the analyses. SD at baseline was more common in females (placebo, 46.4%; vilazodone, 49% than in males (placebo, 35.1%; vilazodone, 40.9%. CSFQ total score improvement was found in both females (placebo, +1.2; vilazodone, +1.6 and males (placebo, +2.1; vilazodone, +1.0, with no statistically significant differences between treatment groups. The percentage of patients who shifted from SD at baseline to normal sexual functioning at EOT was higher in males (placebo, 40.6%; vilazodone, 35.7% than in females (placebo, 24.9%; vilazodone, 34.9%; no statistical testing was performed. Except for erectile dysfunction and delayed ejaculation in vilazodone

  13. Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy

    Directory of Open Access Journals (Sweden)

    Arora S

    2014-06-01

    Full Text Available Sumit Arora,1 Suresh K Swaminathan,2 Ameya Kirtane,2 Sanjeev K Srivastava,1 Arun Bhardwaj,1 Seema Singh,1 Jayanth Panyam,2 Ajay P Singh1,3 1Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA; 2Department of Pharmaceutics, The University of Minnesota, Minneapolis, USA; 3Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile, Alabama, USA Abstract: MicroRNAs are small (18–22 nucleotide long noncoding RNAs that play important roles in biological processes through posttranscriptional regulation of gene expression. Their aberrant expression and functional significance are reported in several human malignancies, including pancreatic cancer. Recently, we identified miR-150 as a novel tumor suppressor microRNA in pancreatic cancer. Furthermore, expression of miR-150 was downregulated in the majority of tumor cases, suggesting that its restoration could serve as an effective approach for pancreatic cancer therapy. In the present study, we developed a nanoparticle-based miR-150 delivery system and tested its therapeutic efficacy in vitro. Using double emulsion solvent evaporation method, we developed a poly (D,L-lactide-co-glycolide (PLGA-based nanoformulation of miR-150 (miR-150-NF. Polyethyleneimine (a cationic polymer was incorporated in PLGA matrix to increase the encapsulation of miR-150. Physical characterization of miR-150-NF demonstrated that these nanoparticles had high encapsulation efficiency (~78% and exhibited sustained release profile. Treatment of pancreatic cancer cells with miR-150-NF led to efficient intracellular delivery of miR-150 mimics and caused significant downregulation of its target gene (MUC4 expression. Inhibition of MUC4 correlated with a concomitant decrease in the expression of its interacting partner, HER2, and repression of its downstream signaling. Furthermore, treatment of pancreatic cancer cells with

  14. Comparative efficacy of long-acting muscarinic antagonist monotherapies in COPD: a systematic review and network meta-analysis

    Directory of Open Access Journals (Sweden)

    Ismaila AS

    2015-11-01

    Full Text Available Afisi Segun Ismaila,1,2 Eline L Huisman,3 Yogesh Suresh Punekar,4 Andreas Karabis31Value Evidence and Outcomes, GlaxoSmithKline, Research Triangle Park, NC, USA; 2Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada; 3Real World Strategy and Analytics, Mapi Group, Houten, the Netherlands; 4Value Evidence and Outcomes, GlaxoSmithKline, Uxbridge, UKBackground: Randomized, controlled trials comparing long-acting muscarinic antagonist (LAMA efficacy in COPD are limited. This network meta-analysis (NMA assessed the relative efficacy of tiotropium 18 µg once-daily (OD and newer agents (aclidinium 400 µg twice-daily, glycopyrronium 50 µg OD, and umeclidinium 62.5 µg OD.Methods: A systematic literature review identified randomized, controlled trials of adult COPD patients receiving LAMAs. A NMA within a Bayesian framework examined change from baseline in trough forced expiratory volume in 1 second (FEV1, transitional dyspnea index focal score, St George’s Respiratory Questionnaire score, and rescue medication use.Results: Twenty-four studies (n=21,311 compared LAMAs with placebo/each other. Aclidinium, glycopyrronium, tiotropium, and umeclidinium, respectively, demonstrated favorable results versus placebo, for change from baseline (95% credible interval in 12-week trough FEV1 (primary endpoint: 101.40 mL [77.06–125.60]; 117.20 mL [104.50–129.90]; 114.10 mL [103.10–125.20]; 136.70 mL [104.20–169.20]; 24-week trough FEV1 (128.10 mL [84.10–172.00]; 135.80 mL [123.10–148.30]; 106.40 mL [95.45–117.30]; 115.00 mL [74.51–155.30]; 24-week St George’s Respiratory Questionnaire score (-4.60 [-6.76 to -2.54]; -3.14 [-3.83 to -2.45]; -2.43 [-2.92 to -1.93]; -4.69 [-7.05 to -2.31]; 24-week transitional dyspnea index score (1.00 [0.41–1.59]; 1.01 [0.79–1.22]; 0.82 [0.62–1.02]; 1.00 [0.49–1.51]; and 24-week rescue medication use (data not available; -0.41 puffs/day [-0.62 to -0.20]; -0.52 puffs/day [-0

  15. Digital Support Interventions for the Self-Management of Low Back Pain: A Systematic Review.

    Science.gov (United States)

    Nicholl, Barbara I; Sandal, Louise F; Stochkendahl, Mette J; McCallum, Marianne; Suresh, Nithya; Vasseljen, Ottar; Hartvigsen, Jan; Mork, Paul J; Kjaer, Per; Søgaard, Karen; Mair, Frances S

    2017-05-21

    -1343 participants per study) and varied considerably in the nature and delivery of the interventions, the duration/definition of LBP, the outcomes measured, and the effectiveness of the interventions. Participants were generally white, middle aged, and in 5 of 6 RCT reports, the majority were female and most reported educational level as time at college or higher. Only one study reported between-group differences in favor of the digital intervention. There was considerable variation in the extent of reporting the characteristics, components, and theories underpinning each intervention. None of the studies showed evidence of harm. The literature is extremely heterogeneous, making it difficult to understand what might work best, for whom, and in what circumstances. Participants were predominantly female, white, well educated, and middle aged, and thus the wider applicability of digital self-management interventions remains uncertain. No information on cost-effectiveness was reported. The evidence base for interactive digital interventions to support patient self-management of LBP remains weak. ©Barbara I Nicholl, Louise F Sandal, Mette J Stochkendahl, Marianne McCallum, Nithya Suresh, Ottar Vasseljen, Jan Hartvigsen, Paul J Mork, Per Kjaer, Karen Søgaard, Frances S Mair. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.05.2017.

  16. Studying and optimizing the biodiesel production from mastic oil aided by ultrasonic using response surface method

    Directory of Open Access Journals (Sweden)

    B Hosseinzdeh Samani

    2016-09-01

    interface. Increasing the ratio of ultrasonic working time to its idling time caused to an increase in the conversion percent. Because the treating time of the samples by ultrasound in limit time durations is increased, while this increase becomes lower at higher ratios. This is due to the fact that the initial vibrative shock acted on the samples after ultrasonic restarting, finds an identical effect with uniform wave. However, the idling phase of ultrasound caused a decrease in the amount of consumed energy. Similar results have been reported by Chand et al. (2010 for the effect of pulse on conversion percent of methyl ester. Trend of reaction time and molar ratio were different with trend of amplitude and molar ratio on methyl ester content so that they were divided to two sections. It should be mentioned that the increase in biodiesel yield because of molar ratio has some limitations. If the ratio is increased more than a certain extent, biodiesel conversion percent will decrease. The main reason for this result can be related to the amount of methanol increase in the mixture, which leads to more dissolution of glycerin and alcohol in biodiesel which considerably influences its purity. Optimization was carried out based on Response Surface Methodology (RSM using Design Experts software. The obtained results from optimization were as follow: 5.45 molar ratio, 0.89 amplitude, 0.71 pulse and 5.99 minutes of time. The conversion percentage obtained as 94.96. It is worthy to note that the experiment was iterated at suggested point by the optimization software and the conversion percent was 94.02. As well as 34792.37 J at the obtained point to be acceptable (1% difference from the model. Conclusions The increase in the ultrasound amplitude resulted in an increase in the conversion percentage which tends to ascend. Also, the increase of reaction time by 5 to 7 minutes increased the conversion percentage, following which is the descend trend. The obtained results from

  17. World Radiopharmaceutical Therapy Council: A report on the 5th International Radiopharmaceutical Therapy Colloquium and the Final Planning Meeting of the World Radiopharmaceutical Therapy Council held at Santiago, Chile, 29 September, 2002

    International Nuclear Information System (INIS)

    Turner, J.V.

    2003-01-01

    -stenosis of coronary arteries following balloon angioplasty was presented by Achim Kropp of Dresden, Amalia Peix of Havana, and June-Key Chung from Seoul who also reported encouraging radiation synovectomy results. Hans Biersack described preliminary studies from Bonn with 188Re MAG3 RC-160 and 188Re-DOTATOC radiopeptides and the potential clinical applications of other 188Re radiopharmaceuticals for radiopeptide therapy and radioimmunotherapy were contemplated, given the daily on-site supply of radionuclide from the 188W/188Re generator. The Final Planning Meeting of the World Radiopharmaceutical Therapy Council, chaired by Harvey Turner, was held during the last session of the Colloquium and discussion was facilitated by a panel of members of the International Task Force of the Council comprising Horacio Amaral, Suresh Srivastava and Alan Perkins. A Preliminary Draft Charter of the World Radiopharmaceutical Therapy Council had been prepared by the Task Force with notable contributions from Sandy McEwan and Chaitanya Divgi and had been circulated to all attendees of the Foundation Planning Meeting of the Council held during the Annual Scientific Meeting of the Society of Nuclear Medicine, June 2001 in Toronto. This draft document was presented for detailed discussion at the Final Planning Meeting in Chile and embodied the principles of global cooperation in therapeutic nuclear medicine outlined in the first issue of the Journal. A Consensus Draft Charter subsequently prepared by the International Task Force was then submitted to the Assembly of Delegates of the World Federation of Nuclear Medicine and Biology on 1st October 2002. The proposal that the World Radiopharmaceutical Therapy Council become an affiliated body of the World Federation of Nuclear Medicine and Biology was adopted without dissent, having been proposed by the President, Horacio Amaral and supported by the Incoming President, Myung Chul Lee. The World Radiopharmaceutical Therapy Council will become an

  18. From the Editor

    Directory of Open Access Journals (Sweden)

    Ugur demiray

    2008-04-01

    NEHME, Prince Mohammad University, Al Khobar, SAUDI ARABIA. This paper directed to faculty members who are already teaching synchronously online or who would like to start teaching synchronously online. It provides best practices, ideas, tips and tricks, and insights to foster successful learning experiences online and ways to think about online synchronous teaching differently than as a mere replicate of traditional campus-based instructional activities. There are two book reviews in this issue. The first book is Web-Based Learning: Theory, Research, and Practice, edited by Harold F. O'Neil, Ray S. Perez, within this framework the book addresses several important issues, including: the primacy of learning as a focus for technology; the need to integrate technology with high standards and content expectations; the paucity of and need to support the development of technology-based curriculum and tools; the need to integrate assessment in technology and improve assessment through the use of technology; and the need for theory-driven research and evaluation studies to increase our knowledge and efficacy The second book review is on Access and Equity: Challenges for Open and Distance Learning and edited by H.P. Dikshit, Suresh Garg, Santosh Panda and Vijayshri. New Delhi, Kogan Page India. To address the issue of access and equity from four different, yet related, perspectives—ODL system: imperatives and responses; curriculum, pedagogy and programmes; research, training and quality assurance; and appropriate technology—international scholars met and shared their experiences recently in an international conference hosted by IGNOU. With their long experience in open distance learning, the editors have collated in the present volume, the best practices and experiences of distance educators the world over, for effective social intervention and national development. It is hoped that contemporary and future practitioners of ODL will benefit from the critical analyses of