WorldWideScience

Sample records for supplemental materials submitted

  1. Supplements to Textbook Materials.

    Science.gov (United States)

    Holmes, Ken

    1994-01-01

    Describes the many kinds of materials that English teachers can draw upon to enrich and expand students' experiences with literature. Outlines ancillary materials used to supplement the study of William Shakespeare's "Julius Caesar." (HB)

  2. Supplementation with vitamin A enhances oxidative stress in the lungs of rats submitted to aerobic exercise.

    Science.gov (United States)

    Gasparotto, Juciano; Petiz, Lyvia Lintzmaier; Girardi, Carolina Saibro; Bortolin, Rafael Calixto; de Vargas, Amanda Rodrigues; Henkin, Bernardo Saldanha; Chaves, Paloma Rodrigues; Roncato, Sabrina; Matté, Cristiane; Zanotto-Filho, Alfeu; Moreira, José Cláudio Fonseca; Gelain, Daniel Pens

    2015-12-01

    Exercise training induces reactive oxygen species production and low levels of oxidative damage, which are required for induction of antioxidant defenses and tissue adaptation. This process is physiological and essential to improve physical conditioning and performance. During exercise, endogenous antioxidants are recruited to prevent excessive oxidative stress, demanding appropriate intake of antioxidants from diet or supplements; in this context, the search for vitamin supplements that enhance the antioxidant defenses and improve exercise performance has been continuously increasing. On the other hand, excess of antioxidants may hinder the pro-oxidant signals necessary for this process of adaptation. The aim of this study was to investigate the effects of vitamin A supplementation (2000 IU/kg, oral) upon oxidative stress and parameters of pro-inflammatory signaling in lungs of rats submitted to aerobic exercise (swimming protocol). When combined with exercise, vitamin A inhibited biochemical parameters of adaptation/conditioning by attenuating exercise-induced antioxidant enzymes (superoxide dismutase and glutathione peroxidase) and decreasing the content of the receptor for advanced glycation end-products. Increased oxidative damage to proteins (carbonylation) and lipids (lipoperoxidation) was also observed in these animals. In sedentary animals, vitamin A decreased superoxide dismutase and increased lipoperoxidation. Vitamin A also enhanced the levels of tumor necrosis factor alpha and decreased interleukin-10, effects partially reversed by aerobic training. Taken together, the results presented herein point to negative effects associated with vitamin A supplementation at the specific dose here used upon oxidative stress and pro-inflammatory cytokines in lung tissues of rats submitted to aerobic exercise.

  3. 18 CFR 154.302 - Previously submitted material.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... concurrently with the rate change filing. There must be furnished to the Director, Office of Energy Market...

  4. 15 CFR 908.7 - Supplemental reports.

    Science.gov (United States)

    2010-01-01

    ... activities submitted under § 908.4, § 908.5, or § 908.6 is found to contain any material inaccuracies, misstatements, and omissions. A supplemental report must also be made if there are changes in plans for the...

  5. Effects of Glutamine and Alanine Supplementation on Central Fatigue Markers in Rats Submitted to Resistance Training

    Directory of Open Access Journals (Sweden)

    Audrey Yule Coqueiro

    2018-01-01

    Full Text Available Recent evidence suggests that increased brain serotonin synthesis impairs performance in high-intensity intermittent exercise and specific amino acids may modulate this condition, delaying fatigue. This study investigated the effects of glutamine and alanine supplementation on central fatigue markers in rats submitted to resistance training (RT. Wistar rats were distributed in: sedentary (SED, trained (CON, trained and supplemented with alanine (ALA, glutamine and alanine in their free form (G + A, or as dipeptide (DIP. Trained groups underwent a ladder-climbing exercise for eight weeks, with progressive loads. In the last 21 days, supplementations were offered in water with a 4% concentration. Albeit without statistically significance difference, RT decreased liver glycogen, and enhanced the concentrations of plasma glucose, free fatty acids (FFA, hypothalamic serotonin, and ammonia in muscle and the liver. Amino acids affected fatigue parameters depending on the supplementation form. G + A prevented the muscle ammonia increase by RT, whereas ALA and DIP augmented ammonia and glycogen concentrations in muscle. DIP also increased liver ammonia. ALA and G + A reduced plasma FFA, whereas DIP increased this parameter, free tryptophan/total tryptophan ratio, hypothalamic serotonin, and the serotonin/dopamine ratio. The supplementations did not affect physical performance. In conclusion, glutamine and alanine may improve or impair central fatigue markers depending on their supplementation form.

  6. Effects of whey protein supplement in the elderly submitted to resistance training: systematic review and meta-analysis.

    Science.gov (United States)

    Colonetti, Tamy; Grande, Antonio Jose; Milton, Karen; Foster, Charlie; Alexandre, Maria Cecilia Manenti; Uggioni, Maria Laura Rodrigues; Rosa, Maria Inês da

    2017-05-01

    We performed a systematic review to map the evidence and analyze the effect of whey protein supplementation in the elderly submitted to resistance training. A comprehensive search on Medline, LILACS, EMBASE, and the Cochrane Library for relevant publications was conducted until August 2015. The terms used in the search were: "Resistance training"; "Whey protein"; "Elderly". A total of 632 studies were screened. Five studies were included composing a sample of 391 patients. The supplement whey protein was associated with higher total protein ingestion 9.40 (95% CI: 4.03-14.78), and with an average change in plasma leucine concentration. The supplementation was also associated with increased mixed muscle protein synthesis 1.26 (95% CI: 0.46-2.07) compared to the control group. We observed an increase in total protein intake, resulting in increased concentration of leucine and mixed muscle protein fractional synthesis rate.

  7. 36 CFR 1206.86 - What additional materials must I submit with the final narrative report?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What additional materials must I submit with the final narrative report? 1206.86 Section 1206.86 Parks, Forests, and Public... narrative report? You must submit the materials determined by the Commission as found in the NHPRC grant...

  8. Particle Suspension Mechanisms - Supplemental Material

    Energy Technology Data Exchange (ETDEWEB)

    Dillon, M B

    2011-03-03

    This supplemental material provides a brief introduction to particle suspension mechanisms that cause exfoliated skin cells to become and remain airborne. The material presented here provides additional context to the primary manuscript and serves as background for designing possible future studies to assess the impact of skin cells as a source of infectious aerosols. This introduction is not intended to be comprehensive and interested readers are encouraged to consult the references cited.

  9. Supplemental Journal Article Materials: A progress report on an information industry initiative

    Science.gov (United States)

    Schwarzman, A. B.

    2011-12-01

    Who could possibly quibble with the idea of publishing supplemental materials to a journal article? Making them available makes it possible for the Earth and space scientists to demonstrate supporting evidence, such as multimedia, computer programs, and datasets; gives the authors the opportunity to present in-depth studies that would not otherwise be available; and enables the readers to replicate experiments and verify their results. However, the scholarly publishing ecosystem is now being threatened by a veritable tsunami of supplemental materials that have to be peer reviewed, identified, described, and made discoverable and citeable; such materials also have to be archived, preserved, and perpetually converted to the contemporary formats to be available to a future researcher. Moreover, the readers often have no clear indication of how critical a particular supplemental material is to the scientific conclusions of the article and thus are not sure whether they should spend their time reading/viewing/running it. In some cases it is not even clear what the material actually supplements. While one segment of the research community argues that even more supplemental materials should be made available, another segment increasingly voices its concern stating categorically that a research article is not a data dump or an FTP site. From the publisher's perspective, dealing with supplemental materials in a responsible fashion is becoming an increasingly costly proposition. Faced with formidable challenges of managing supplemental materials, the information profession community in 2010 formed a joint NISO/NFAIS Working Group to develop Recommended Practices for curating supplemental materials during their life cycle, including but not limited to their selection, peer review, editing, production, presentation, providing context, identification, linking, citing, hosting, discovery, metadata and markup, packaging, accessibility, and preservation. The Recommended Practices

  10. The effects of coconut oil supplementation on the body composition and lipid profile of rats submitted to physical exercise

    Directory of Open Access Journals (Sweden)

    NATHÁLIA M. RESENDE

    2016-06-01

    Full Text Available This study aims to verify the effects of coconut oil supplementation (COS in the body composition and lipid profile of rats submitted to physical exercise. The animals (n=6 per group were randomly assigned to: G1=Sedentary and Non-supplemented (Control Group, G2=Sedentary and Supplemented, G3=Exercised and Non-supplemented and G4=Exercised and Supplemented. The COS protocol used was 3 mL/Kg of body mass by gavage for 28 days. The physical exercise was the vertical jumping training for 28 days. It was determined the body mass parameters, Lee Index, blood glucose and lipid profile. The COS did not interfere with body mass, but the lean body mass was lower in G3 compared to G2. The final Lee Index classified G1 and G2 as obese (>30g/cm. The lipid profile showed total cholesterol was decreased in G3, LDL-c concentration was decreased in G2, triglycerides, VLDL-c and HDL-c concentrations were increased in G2 and G4 in relation to G1 and G3. The COS decreased LDL-c/HDL-c ratio. In conclusion, the COS associated or not to physical exercise worsen others lipid parameters, like triglycerides and VLDL-c level, showing the care with the use of lipid supplements.

  11. Vitamin and Mineral Supplement Fact Sheets

    Science.gov (United States)

    ... website Submit Search NIH Office of Dietary Supplements Vitamin and Mineral Supplement Fact Sheets Search the list ... Supplements: Background Information Botanical Dietary Supplements: Background Information Vitamin and Mineral Fact Sheets Botanical Supplement Fact Sheets ...

  12. 18 CFR 35.5 - Rejection of material submitted for filing.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Rejection of material submitted for filing. 35.5 Section 35.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... that fails to comply with this Part may be rejected by the Director of the Office of Energy Market...

  13. The effects of a high dosage of creatine and caffeine supplementation on the lean body mass composition of rats submitted to vertical jumping training

    Directory of Open Access Journals (Sweden)

    Carneiro-Junior Miguel A

    2011-03-01

    Full Text Available Abstract Background The influences of creatine and caffeine supplementation associated with power exercise on lean body mass (LBM composition are not clear. The purpose of this research was to determine whether supplementation with high doses of creatine and caffeine, either solely or combined, affects the LBM composition of rats submitted to vertical jumping training. Methods Male Wistar rats were randomly divided into 8 groups: Sedentary (S or Exercised (E [placebo (Pl, creatine (Cr, caffeine (Caf or creatine plus caffeine (CrCaf]. The supplemented groups received creatine [load: 0.430 g/kg of body weight (BW for 7 days; and maintenance: 0.143 g/kg of BW for 35 days], caffeine (15 mg/kg of BW for 42 days or creatine plus caffeine. The exercised groups underwent a vertical jump training regime (load: 20 - 50% of BW, 4 sets of 10 jumps interspersed with 1 min resting intervals, 5 days/wk, for 6 weeks. LBM composition was evaluated by portions of water, protein and fat in the rat carcass. Data were submitted to ANOVA followed by the Tukey post hoc test and Student's t test. Results Exercised animals presented a lower carcass weight (10.9%; P = 0.01, as compared to sedentary animals. However, no effect of supplementation was observed on carcass weight (P > 0.05. There were no significant differences among the groups (P > 0.05 for percentage of water in the carcass. The percentage of fat in the group SCr was higher than in the groups SCaf and ECr (P Conclusions High combined doses of creatine and caffeine does not affect the LBM composition of either sedentary or exercised rats, however, caffeine supplementation alone reduces the percentage of fat. Vertical jumping training increases the percentages of water and protein and reduces the fat percentage in rats.

  14. 7 CFR 1955.22 - State supplements.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true State supplements. 1955.22 Section 1955.22 Agriculture... Real and Chattel Property § 1955.22 State supplements. State Supplements will be prepared with the... supplements will be submitted to the National Office for post approval in accordance with FmHA or its...

  15. The effects of a high dosage of creatine and caffeine supplementation on the lean body mass composition of rats submitted to vertical jumping training.

    Science.gov (United States)

    Franco, Frederico Sc; Costa, Neuza Mb; Ferreira, Susana A; Carneiro-Junior, Miguel A; Natali, Antônio J

    2011-03-01

    The influences of creatine and caffeine supplementation associated with power exercise on lean body mass (LBM) composition are not clear. The purpose of this research was to determine whether supplementation with high doses of creatine and caffeine, either solely or combined, affects the LBM composition of rats submitted to vertical jumping training. Male Wistar rats were randomly divided into 8 groups: Sedentary (S) or Exercised (E) [placebo (Pl), creatine (Cr), caffeine (Caf) or creatine plus caffeine (CrCaf)]. The supplemented groups received creatine [load: 0.430 g/kg of body weight (BW) for 7 days; and maintenance: 0.143 g/kg of BW for 35 days], caffeine (15 mg/kg of BW for 42 days) or creatine plus caffeine. The exercised groups underwent a vertical jump training regime (load: 20 - 50% of BW, 4 sets of 10 jumps interspersed with 1 min resting intervals), 5 days/wk, for 6 weeks. LBM composition was evaluated by portions of water, protein and fat in the rat carcass. Data were submitted to ANOVA followed by the Tukey post hoc test and Student's t test. Exercised animals presented a lower carcass weight (10.9%; P = 0.01), as compared to sedentary animals. However, no effect of supplementation was observed on carcass weight (P > 0.05). There were no significant differences among the groups (P > 0.05) for percentage of water in the carcass. The percentage of fat in the group SCr was higher than in the groups SCaf and ECr (P < 0.05). A higher percentage of protein was observed in the groups EPl and ECaf when compared to the groups SPl and SCaf (P < 0.001). The percentage of fat in the carcass decreased (P < 0.001), while those of water and protein increased (P < 0.05) in exercised animals, compared to sedentary animals. Caffeine groups presented reduced percentage of fat when compared to creatine supplemented groups (P < 0.05). High combined doses of creatine and caffeine does not affect the LBM composition of either sedentary or exercised rats, however, caffeine

  16. Characteristics and trends of drug and dietary supplement inquiries by college athletes.

    Science.gov (United States)

    Ambrose, Peter J; Tsourounis, Candy; Uryasz, Frank D; Patterson, Eric

    2013-01-01

    To characterize the types of drug and dietary supplement inquiries submitted to the National Center for Drug Free Sport through the Resource Exchange Center (REC). Cross-sectional study. United States, from July 2009 through June 2010. Athletes and athletic personnel associated with the National Collegiate Athletic Association (NCAA). Tabulation and classification of drugs and dietary supplement inquiries. Characteristics and trends of drug and dietary supplement inquiries. Inquiries for prescription medications for albuterol inhalers, methylphenidate, amphetamines, and prednisone were the most common using a drug lookup function. The most common inquiries for over-the-counter medications included pseudoephedrine, loratadine, cetirizine, and caffeine. Among dietary supplements, inquiries for amino acids/metabolites, vitamins and minerals, and herbal products occurred most frequently. One dietary supplement, N.O.-Xplode (Bio-Engineered Supplements and Nutrition, Inc.), accounted for the majority of individual dietary supplement inquiries. Banned substances accounted for 30% of all inquiries submitted to the REC and 18% of medications searched in a drug lookup database. Almost 25,000 inquiries were submitted to the REC. Pharmacists can use this information to advise, counsel, and refer NCAA athletes regarding the use of banned and permitted substances. Education programs regarding stimulants, dietary supplements, and the risk of using substances such as animal byproducts are needed, and pharmacists can participate in these programs.

  17. Regulations for the safe transport of radioactive material. 1985 ed. Supplement 1988

    International Nuclear Information System (INIS)

    1988-01-01

    A major revision of the Agency's Regulations for the Safe Transport of Radioactive Material, Safety Series No. 6, was undertaken during a period of several years, culminating in the publication of the 1985 Edition. In order to consider minor problems in the new edition, the Agency convened a panel of experts in January 1986. This panel recommended some amendments which were subsequently published as Supplement 1986 to the Regulations. A further review panel meeting took place in June 1987. The amendments which were recommended for early adoption were themselves divided into two kinds. The first of these are designated as minor changes. The second kind of amendment recommended for early adoption comprises actual changes to regulatory provisions. Several changes of this second type were recommended by the panel and are included in this Supplement. The Supplement also contains the amended texts of the supporting documents, Safety Series Nos 7, 37 and 80, which are necessary to correct minor errors as well as to provide complementary information for the changes introduced to the Regulations themselves. In addition, the Supplement embodies the contents of Supplement 1986, which is consequently superseded.

  18. Application of the instructional congruence framework: Developing supplemental materials for English language learners

    Science.gov (United States)

    Drews, Tina Skjerping

    2009-12-01

    This dissertation is a study of the instructional congruence framework as it was used to develop and pilot a supplemental science unit on energy and the environment for sixth grade students in Arizona. With the growing linguistic and cultural diversity of children in American schools, congruent materials are more important now than ever before. The supplemental materials were designed by the researcher and underwent a six person, three educator and three engineer, panel review. The revised materials were then piloted in two sixth grade classrooms in the Southwest with high numbers of English language learners. Classroom observation, teacher interviews, and the classroom observation protocol were utilized to understand the fidelity to the instructional congruence framework. The fidelity of implementation of materials was subject to the realities of varied educational contexts. Piloting materials in urban contexts with diverse students involved additional challenges. The results of the study explore the challenges in creating instructionally congruent materials for diverse students in urban contexts. Recommendations are provided for curriculum developers that undertake the task of creating instructionally congruent materials and emphasize the need to devise innovative methods of creation, while understanding that there is no perfect solution. The education community as a whole could benefit from incorporating and synthesizing the instructional congruence framework in order to provide maximum opportunities in science for all students.

  19. Structuring supplemental materials in support of reproducibility.

    Science.gov (United States)

    Greenbaum, Dov; Rozowsky, Joel; Stodden, Victoria; Gerstein, Mark

    2017-04-05

    Supplements are increasingly important to the scientific record, particularly in genomics. However, they are often underutilized. Optimally, supplements should make results findable, accessible, interoperable, and reusable (i.e., "FAIR"). Moreover, properly off-loading to them the data and detail in a paper could make the main text more readable. We propose a hierarchical organization for supplements, with some parts paralleling and "shadowing" the main text and other elements branching off from it, and we suggest a specific formatting to make this structure explicit. Furthermore, sections of the supplement could be presented in multiple scientific "dialects", including machine-readable and lay-friendly formats.

  20. Structuring supplemental materials in support of reproducibility

    OpenAIRE

    Greenbaum, Dov; Rozowsky, Joel; Stodden, Victoria; Gerstein, Mark

    2017-01-01

    Supplements are increasingly important to the scientific record, particularly in genomics. However, they are often underutilized. Optimally, supplements should make results findable, accessible, interoperable, and reusable (i.e., ?FAIR?). Moreover, properly off-loading to them the data and detail in a paper could make the main text more readable. We propose a hierarchical organization for supplements, with some parts paralleling and ?shadowing? the main text and other elements branching off f...

  1. SKI's evaluation of SKB's Supplement to RD and D Programme 92

    International Nuclear Information System (INIS)

    1995-05-01

    On December 16, 1993, the Government decided (M93/2525/6), with regard to the 1992 Programme for Research, Development, Demonstration and Other Measures (RD and D Programme 92), compiled by the Swedish Nuclear Fuel and Waste Management Co (SKB) in accordance with Section 12 of the Act on Nuclear Activities, that RD and D Programme 92 should be supplemented by SKB in the manner specified in the decision. On August 19, 1992, SKB submitted the requested supplement to the Swedish Nuclear Power Inspectorate (SKI). SKI has examined the supplement and has requested and obtained comments from a large number of reviewing bodies. SKI hereby submits the documents on the matter along with its own review report. The review report contains an evaluation of SKB's supplement in relation to the government decision and certain recommendations for the structuring of the licensing procedure for planned facilities. These recommendations have taken into account the statements of the reviewing bodies

  2. Re: Supplement to Request for Correction - IRIS Assessment of Trichloroethylene

    Science.gov (United States)

    Letter from Faye Graul providing supplemental information to her Request for Correction for Threshold of Trichloroethylene Contamination of Maternal Drinking Waters submitted under the Information Quality Act.

  3. Rosemary supplementation (Rosmarinus oficinallis L. attenuates cardiac remodeling after myocardial infarction in rats.

    Directory of Open Access Journals (Sweden)

    Bruna Paola Murino Rafacho

    Full Text Available Myocardial infarction (MI is one of the leading causes of morbidity and mortality worldwide. Dietary intervention on adverse cardiac remodeling after MI has significant clinical relevance. Rosemary leaves are a natural product with antioxidant/anti-inflammatory properties, but its effect on morphology and ventricular function after MI is unknown.To determine the effect of the dietary supplementation of rosemary leaves on cardiac remodeling after MI, male Wistar rats were divided into 6 groups after sham procedure or experimental induced MI: 1 Sham group fed standard chow (SR0, n = 23; 2 Sham group fed standard chow supplemented with 0.02% rosemary (R002 (SR002, n = 23; 3 Sham group fed standard chow supplemented with 0.2% rosemary (R02 (SR02, n = 22; 4 group submitted to MI and fed standard chow (IR0, n = 13; 5 group submitted to MI and fed standard chow supplemented with R002 (IR002, n = 8; and 6 group submitted to MI and fed standard chow supplemented with R02 (IR02, n = 9. After 3 months of the treatment, systolic pressure evaluation, echocardiography and euthanasia were performed. Left ventricular samples were evaluated for: fibrosis, cytokine levels, apoptosis, energy metabolism enzymes, and oxidative stress. Rosemary dietary supplementation attenuated cardiac remodeling by improving energy metabolism and decreasing oxidative stress. Rosemary supplementation of 0.02% improved diastolic function and reduced hypertrophy after MI. Regarding rosemary dose, 0.02% and 0.2% for rats are equivalent to 11 mg and 110 mg for humans, respectively.Our findings support further investigations of the rosemary use as adjuvant therapy in adverse cardiac remodeling.

  4. 76 FR 58122 - Defense Federal Acquisition Regulation Supplement; Material Inspection and Receiving Report...

    Science.gov (United States)

    2011-09-20

    ... acceptance point and replacing it with more specific data entries for inspection, acceptance, and ship to Do..., acceptance, and ship-to fields but kept the source, destination, and other inspection and acceptance points... Acquisition Regulation Supplement; Material Inspection and Receiving Report (DFARS Case 2009-D023) AGENCY...

  5. 75 FR 68321 - Forage Genetics International; Supplemental Request for Partial Deregulation of Roundup Ready...

    Science.gov (United States)

    2010-11-05

    ...] Forage Genetics International; Supplemental Request for Partial Deregulation of Roundup Ready Alfalfa... Inspection Service has received a supplemental request for ``partial deregulation'' from Forage Genetics... affected persons of the availability of the documents submitted to the Agency from Forage Genetics...

  6. P2X(7 receptor in the kidneys of diabetic rats submitted to aerobic training or to N-acetylcysteine supplementation [corrected].

    Directory of Open Access Journals (Sweden)

    Adelson M Rodrigues

    Full Text Available Previous studies in our laboratory showed that N-acetylcysteine supplementation or aerobic training reduced oxidative stress and the progression of diabetic nephropathy in rats. The P2X(7 receptor is up-regulated in pathological conditions, such as diabetes mellitus. This up-regulation is related to oxidative stress and induces tissue apoptosis or necrosis. The aim of the present study is to assess the role of P2X(7 receptor in the kidneys of diabetic rats submitted to aerobic training or N-acetylcysteine supplementation. Diabetes was induced in male Wistar rats by streptozotocin (60 mg/kg, i.v. and the training was done on a treadmill; N-acetylcysteine was given in the drinking water (600 mg/L. By confocal microscopy, as compared to control, the kidneys of diabetic rats showed increased P2 × 7 receptor expression and a higher activation in response to 2'(3'-O-(4-benzoylbenzoyl adenosine5'-triphosphate (specific agonist and adenosine triphosphate (nonspecific agonist (all p<0.05. All these alterations were reduced in diabetic rats treated with N-acetylcysteine, exercise or both. We also observed measured proteinuria and albuminuria (early marker of diabetic nephropathy in DM groups. Lipoperoxidation was strongly correlated with P2X(7 receptor expression, which was also correlated to NO•, thus associating this receptor to oxidative stress and kidney lesion. We suggest that P2X(7 receptor inhibition associated with the maintenance of redox homeostasis could be useful as coadjuvant treatment to delay the progression of diabetic nephropathy.

  7. P2X(7) receptor in the kidneys of diabetic rats submitted to aerobic training or to N-acetylcysteine supplementation [corrected].

    Science.gov (United States)

    Rodrigues, Adelson M; Bergamaschi, Cassia T; Fernandes, Maria Jose S; Paredes-Gamero, Edgar J; Buri, Marcus V; Curi, Marcus V; Ferreira, Alice T; Araujo, Sergio R R; Punaro, Giovana R; Maciel, Fabiane R; Nogueira, Guilherme B; Higa, Elisa M S

    2014-01-01

    Previous studies in our laboratory showed that N-acetylcysteine supplementation or aerobic training reduced oxidative stress and the progression of diabetic nephropathy in rats. The P2X(7 receptor is up-regulated in pathological conditions, such as diabetes mellitus. This up-regulation is related to oxidative stress and induces tissue apoptosis or necrosis. The aim of the present study is to assess the role of P2X(7) receptor in the kidneys of diabetic rats submitted to aerobic training or N-acetylcysteine supplementation. Diabetes was induced in male Wistar rats by streptozotocin (60 mg/kg, i.v.) and the training was done on a treadmill; N-acetylcysteine was given in the drinking water (600 mg/L). By confocal microscopy, as compared to control, the kidneys of diabetic rats showed increased P2 × 7 receptor expression and a higher activation in response to 2'(3')-O-(4-benzoylbenzoyl) adenosine5'-triphosphate (specific agonist) and adenosine triphosphate (nonspecific agonist) (all p<0.05). All these alterations were reduced in diabetic rats treated with N-acetylcysteine, exercise or both. We also observed measured proteinuria and albuminuria (early marker of diabetic nephropathy) in DM groups. Lipoperoxidation was strongly correlated with P2X(7) receptor expression, which was also correlated to NO•, thus associating this receptor to oxidative stress and kidney lesion. We suggest that P2X(7) receptor inhibition associated with the maintenance of redox homeostasis could be useful as coadjuvant treatment to delay the progression of diabetic nephropathy.

  8. Data on trapping and re-emission of energetic hydrogen isotopes and helium in materials, supplement 1

    International Nuclear Information System (INIS)

    Yamaguchi, Sadae; Sugizaki, Yasuaki; Ozawa, Kunio; Nakai, Yohta.

    1984-05-01

    This is the supplement to the data on trapping and re-emission of energetic hydrogen isotopes and helium in materials (JAERI-M 82-118). It contains 32 data up to end of 1982, dividing it into following 6 sections: 1) Dose Dependence, 2) Target Material Dependence, 3) Target Temperature Dependence, 4) Incident Energy Dependence, 5) Damage Effects and 6) Ion-Induced Release. (author)

  9. 78 FR 63462 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement...

    Science.gov (United States)

    2013-10-24

    ... Relating to Organizational Conflict of Interest-Major Defense Acquisition Program; OMB Control Number 0704...] Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Organizational Conflict... submit comments, identified by OMB Control Number 0704-0477, using any of the following methods: [cir...

  10. 78 FR 64442 - NASA FAR Supplement: Proposal Adequacy Checklist

    Science.gov (United States)

    2013-10-29

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 48 CFR Parts 1815 and 1852 RIN 2700-AE13 NASA FAR...: Proposed rule. SUMMARY: NASA is proposing to amend the NASA FAR Supplement (NFS) to incorporate a proposal... or pricing data. DATES: Interested parties should submit comments to NASA at the address below on or...

  11. Deposition of carotenoids in egg yolk by short-term supplement of coloured carrot (Daucus carota) varieties as forage material for egg-laying hens.

    Science.gov (United States)

    Hammershøj, Marianne; Kidmose, Ulla; Steenfeldt, Sanna

    2010-05-01

    Supplying egg-laying hens with different forage materials may influence egg production and quality. The aim of this study was to examine the short-term effects of standard feed plus 70 g day(-1) per hen of three coloured carrot varieties (orange, yellow and purple) as forage material in comparison with a standard feed control on egg production, egg yolk colour and deposition of carotenoids in the yolk. Carrot supplementation reduced feed intakes significantly, but not on a dry matter basis. Orange carrot treatment significantly reduced egg mass production, whereas yellow and purple carrot treatments did not differ from the control. Egg and yolk weights of all carrot-supplemented treatments were significantly lower than those of the control, but yolk percentages were similar. Yolk redness increased significantly in the order control 1.5-fold) and beta-carotene (>100-fold) compared with the control. Supplementing the feed of egg-laying hens with coloured carrots efficiently increased yolk colour parameters and carotenoid contents, which gives opportunities for improved nutritional value of eggs from forage material-supplemented hens.

  12. Assessment of the effect of prolonged forced swimming on CD-1 mice sperm morphology with and without antioxidant supplementation.

    Science.gov (United States)

    Rodriguez, I; Diaz, A; Vaamonde, D

    2016-04-01

    As physical exercise has been shown to negatively affect sperm morphology, this study was undertaken to assess the effect of a 3-min forced swimming protocol during 50 days, with and without administration of antioxidants [N-acetylcysteine (NAC) and trans-resveratrol], on sperm morphology in CD-1 mice. Forty-four 13-week-old CD-1 mice were randomly allocated to four different groups: mice not submitted to exercise, control group (CG), mice submitted to swimming without administration of antioxidants (EX), mice submitted to swimming that received trans-resveratrol supplementation [exercise group (EX)+Resv] and mice submitted to swimming exercise that received NAC supplementation (EX+NAC). The EX showed 30.5% of spermatozoa with normal morphology, showing significant differences with regard to the CG, which showed 58.5%. The groups receiving antioxidant supplements showed significantly higher percentages of spermatozoa with normal morphology in comparison with the EX group (EX+Resv: 64.1%, EX+NAC: 48.2%). The imposed model of forced swimming caused alterations in sperm morphology. The antioxidants employed seem to be suitable antioxidants for avoiding exercise-associated sperm morphology anomalies in prolonged forced swimming exercise. Trans-resveratrol has proven to be more efficient for this purpose. © 2015 Blackwell Verlag GmbH.

  13. Alternative sources of supplements for Africanized honeybees submitted to royal jelly production

    OpenAIRE

    Sereia, Maria Josiane; Toledo, Vagner de Alencar Arnaut de; Furlan, Antonio Claudio; Faquinello, Patrícia; Maia, Fabiana Martins Costa; Wielewski, Priscila

    2013-01-01

    This study was carried out to evaluate the effect of supplements with isolated soy protein, brewer's yeast, a mixture of isolated soy protein with brewer's yeast, linseed oil, palm oil and mixture of linseed oil with palm oil in the production of royal jelly by Africanized honeybee colonies. Total royal jelly production was higher (p < 0.05) in colonies fed with isolated soy protein and brewer's yeast (11.68 g colony-1), followed by linseed oil and palm oil (11.30 g colony-1) and palm oil (9....

  14. 77 FR 20367 - Proposed Information Collection; Comment Request; Computer and Internet Use Supplement to the...

    Science.gov (United States)

    2012-04-04

    ... DEPARTMENT OF COMMERCE National Telecommunications and Information Administration Proposed Information Collection; Comment Request; Computer and Internet Use Supplement to the Census Bureau's Current... of automated collection techniques or other forms of information technology. Comments submitted in...

  15. EXERCISE X BCAA SUPPLEMENTATION IN YOUNG TRAINED RATS: WHAT ARE THEIR EFFECTS ON BODY GROWTH?

    Directory of Open Access Journals (Sweden)

    Patricia Lopes de Campos-Ferraz

    2011-09-01

    Full Text Available The purpose of this study was to evaluate whether Branched-chain amino acids (BCAAs supplementation had any beneficial effects on growth and metabolic parameters of young rats submitted to chronic aerobic exercise. Thirty-two young rats (age: 21-d were randomly assigned to four experimental groups (n = 8: Supplemented Trained (Sup/Ex, Control Trained (Ctrl/Ex, Supplemented Sedentary (Sup/Sed and Control Sedentary (Ctrl/Sed. The trained groups underwent a five-week swimming protocol and received supplemented (45 mg BCAA/body weight/day or control ration. Trained animals presented a lower body length and a higher cartilage weight, regardless of supplementation. Physical activity was responsible for a substantial reduction in proteoglycan synthesis in cartilage tissue, and BCAA supplementation was able to attenuate this reduction and also to improve glycogen stores in the liver, although no major differences were found in body growth associated to this supplementation

  16. Acute effect of caffeine supplementation on performance of muscular strength and cardiovascular changes during resistance training

    Directory of Open Access Journals (Sweden)

    W. Materko

    2011-01-01

    Full Text Available The purpose of the present study was to evaluate the acute effect of caffeine on the muscular strength performance in addition to the possible hemodynamic changes during a strength training session. Thirteen strength training experienced male subjects were submitted to a protocol of three sets of 10RM for bench press (BP, pull press (PP, leg extension (LE and leg curl (LC, according to three conditions: no supplementation (C; 250 mg of caffeine supplementation (S; placebo (P. All subjects were submitted to an anthropometric evaluation, followed by a 10RM familiarization test. Hemodynamic measurements – heart rate (HR and blood pressure (BP – were carried out before, during and after each session. Holding 48 hours time intervals, participants were submitted to three randomly presented 10RM tests according to C, S and P conditions. For conditions S and C, significant differences were found in BP and LE. No significant differences in HR and BP were found. Results seem to suggest an ergogenic effect of caffeine on submaximal muscle strength during a session of strength training.

  17. From the Editor: An Introduction to the JSLHR Supplement on Implementation Science.

    Science.gov (United States)

    Paul, Rhea

    2015-12-01

    The JSLHR Supplement on Implementation Science is aimed at providing discussion and examples of research in implementation science, the study of methods designed to promote the incorporation of research findings into clinical practice. Practitioners in the language science area were invited to submit articles that address their experience with various aspects of implementation science. Six articles from several research groups comprise this supplement. Implementation science is an aspect of intervention research that merits consideration by communication disorders scientists. More extensive practice of implementation science will improve uptake of evidence-based practice in the clinical community.

  18. Supplemental materials for the ICDP-USGS Eyreville A, B, and C core holes, Chesapeake Bay impact structure: Core-box photographs, coring-run tables, and depth-conversion files

    Science.gov (United States)

    Durand, C.T.; Edwards, L.E.; Malinconico, M.L.; Powars, D.S.

    2009-01-01

    During 2005-2006, the International Continental Scientific Drilling Program and the U.S. Geological Survey drilled three continuous core holes into the Chesapeake Bay impact structure to a total depth of 1766.3 m. A collection of supplemental materials that presents a record of the core recovery and measurement data for the Eyreville cores is available on CD-ROM at the end of this volume and in the GSA Data Repository. The supplemental materials on the CD-ROM include digital photographs of each core box from the three core holes, tables of the three coring-run logs, as recorded on site, and a set of depth-conversion programs. In this chapter, the contents, purposes, and basic applications of the supplemental materials are briefly described. With this information, users can quickly decide if the materials will apply to their specific research needs. ?? 2009 The Geological Society of America.

  19. Efeitos da suplementação de creatina na captação de glicose em ratos submetidos ao exercício físico Effects of creatine supplementation on glucose uptake in rats submitted to exercise training

    Directory of Open Access Journals (Sweden)

    Thiago Onofre Freire

    2008-10-01

    Full Text Available Estudos recentes têm sugerido que a suplementação de creatina é capaz de modular a homeostase da glicose, aumentando sua captação pelos tecidos periféricos. O objetivo deste trabalho foi investigar o efeito da suplementação de creatina na tolerância à glicose e no conteúdo de glicogênio muscular e hepático em ratos submetidos ou não à atividade física por quatro e oito semanas. Ratos Wistar foram divididos em dois grupos: quatro e oito semanas de intervenção. Posteriormente, cada grupo foi subdividido em quatro subgrupos, de acordo com a ingestão do suplemento e o treinamento: controle cedentário, controle treinado, suplementado sedentário e suplementado treinado. Os animais tiveram livre acesso à água e ração; o grupo suplementado teve 2% de sua ração sob a forma de creatina monoidratada. Os grupos exercitados nadaram 40 minutos por dia, quatro dias por semana, com carga entre 2 e 5% do seu peso amarrado ao peito. Após quatro e oito semanas, o teste oral de tolerância à glicose e as dosagens de glicogênio muscular e hepático foram realizadas. Não foram observadas diferenças significativas entre os grupos no teste de tolerância oral à glicose e no conteúdo de glicogênio muscular e hepático. Este estudo mostrou que a suplementação de creatina não exerceu influência na tolerância à glicose nem nas concentrações de glicogênio em ratos submetidos ou não à atividade física por quatro ou oito semanas.Recently, studies have suggested that creatine supplementation can modulate glucose homeostasis by increasing glucose uptake in peripheral tissues. The aim of this study was to investigate the effects of creatine supplementation on glucose tolerance, muscle and hepatic glycogen content in rats submitted or not to physical activity for four and eight weeks. Wistar rats were divided in two groups: four and eight weeks of intervention. Afterwards, each group was subdivided in four subgroups, according to

  20. Safety Evaluation Report related to the operation of Fermi-2 (Docket No. 50-341). Supplement No. 5

    International Nuclear Information System (INIS)

    1985-03-01

    Supplement No. 5 to the Safety Evaluation Report (SER) related to the operation of the Fermi-2 facility, provides the NRC staff's evaluation of additional information submitted by the applicant regarding outstanding review issues identified in Supplement No. 4 to the SER dated September 1984. This supplement contains the staff's conclusion that there are no outstanding issues which must be resolved prior to issuance of a low-power operating license (i.e., less than five percent of full rated power) for the Fermi-2 facility. Supplement No. 5 to the SER also summarizes the conditions which are placed in the Fermi-2 operating license

  1. Safety Evaluation Report related to the operation of Enrico Fermi Atomic Power Plant, Unit No. 2 (Docket No. 50-341). Supplement No. 4

    International Nuclear Information System (INIS)

    1984-09-01

    Supplement No. 4 to the Safety Evaluation Report related to the operation of the Enrico Fermi Atomic Power Plant, Unit 2, provides the staff's evaluation of additional information submitted by the applicant regarding outstanding review issues identified in Supplement No. 3 to the Safety Evaluation Report, dated January 1983

  2. Conceptual design report: Nuclear materials storage facility renovation. Part 3, Supplemental information

    International Nuclear Information System (INIS)

    1995-01-01

    The Nuclear Materials Storage Facility (NMSF) at the Los Alamos National Laboratory (LANL) was a Fiscal Year (FY) 1984 line-item project completed in 1987 that has never been operated because of major design and construction deficiencies. This renovation project, which will correct those deficiencies and allow operation of the facility, is proposed as an FY 97 line item. The mission of the project is to provide centralized intermediate and long-term storage of special nuclear materials (SNM) associated with defined LANL programmatic missions and to establish a centralized SNM shipping and receiving location for Technical Area (TA)-55 at LANL. Based on current projections, existing storage space for SNM at other locations at LANL will be loaded to capacity by approximately 2002. This will adversely affect LANUs ability to meet its mission requirements in the future. The affected missions include LANL's weapons research, development, and testing (WRD ampersand T) program; special materials recovery; stockpile survelliance/evaluation; advanced fuels and heat sources development and production; and safe, secure storage of existing nuclear materials inventories. The problem is further exacerbated by LANL's inability to ship any materials offsite because of the lack of receiver sites for mate rial and regulatory issues. Correction of the current deficiencies and enhancement of the facility will provide centralized storage close to a nuclear materials processing facility. The project will enable long-term, cost-effective storage in a secure environment with reduced radiation exposure to workers, and eliminate potential exposures to the public. It is organized into seven parts. Part I - Design Concept describes the selected solution. Part III - Supplemental Information contains calculations for the various disciplines as well as other supporting information and analyses

  3. 78 FR 65221 - Defense Federal Acquisition Regulation Supplement: New Free Trade Agreement-Panama (DFARS Case...

    Science.gov (United States)

    2013-10-31

    ... Supplement (DFARS) to implement the United States--Panama Trade Promotion Agreement. This Trade Promotion...--Panama Trade Promotion Agreement. No respondents submitted public comments in response to the interim... effects, distributive impacts, and equity). E.O. 13563 emphasizes the importance of quantifying both costs...

  4. Impact of supplemental instruction leader on the success of supplemental instruction model

    Science.gov (United States)

    Mahabaduge, Hasitha; Haslam, Jeanne

    Supplemental instruction utilizes peer-assisted study sessions to provide review sessions on course material and an opportunity to discuss and work out problems. The impact of supplemental instruction on student performance is well researched and used in a large number of universities around the world due to its proven success. However, the impact of the student leader who plays a significant role in this model is rarely discussed in the literature. We present a case study on the impact of student leader on the success of supplemental instruction model. This case study was done for an Introductory Physics course correlating student performance and the supplemental instruction sessions they attended. Further analysis revealed that the academic performance and work ethics of the student leader has a significant impact on the success of the supplemental instruction model. Important factors to consider when selecting a student leader, the challenges and possible remedies will also be discussed.

  5. Cellulose, hemicelluloses, lignin and ash content of some organic materials and their suitability for use as paper pulp supplements.

    Science.gov (United States)

    Ververis, C; Georghiou, K; Danielidis, D; Hatzinikolaou, D G; Santas, P; Santas, R; Corleti, V

    2007-01-01

    Freshwater algal biomass and orange and lemon peels were assessed as tissue paper pulp supplements. Cellulose and hemicellulose contents of algal biomass were 7.1% and 16.3%, respectively, whereas for citrus peels cellulose content ranged from 12.7% to 13.6% and hemicellulose from 5.3% to 6.1%. For all materials, lignin and ash content was 2% or lower, rendering them suitable for use as paper pulp supplements. The addition of algal biomass to paper pulp increased its mechanical strength significantly. However, brightness was adversely affected by chlorophyll. The addition of citrus peels in paper pulp had no effect on breaking length, increased bursting strength and decreased tearing resistance. Brightness was negatively affected at proportions of 10%, because citrus peel particles behave as coloured pigments. The cost of both materials is about 45% lower than that of conventional pulp, resulting in a 0.9-4.5% reduction in final paper price upon their addition to the pulp.

  6. Supplementation of irradiated and non-irradiated cowpea bean (Vigna unguiculata L. Walp) protein with cereal proteins - supplementation of soup with a protein blend of appropriate nutritional value

    International Nuclear Information System (INIS)

    Dario, A.C.; Salgado, J.M.

    1994-01-01

    The quality of the cowpea bean protein was improved through supplementations with flours from beans exposed to microwave oven treated with cereal proteins such as wheat, rice, corn, and sorghum. Biological assays results with these blends showed that the casein exceeded the other diets concerning digestibility only; however, in parameters such as biological value, net protein utilization (NPU), protein efficiency ratio (PER) and nutritional efficiency ratio (NER), no significant differences occurred. Among all elaborated blends, the one with irradiated beans submitted to microwave oven for 30 minutes (65%) + rice (35%) presented the best results. The soup elaborated with the best supplemented blend was satisfactory concerning color, odor, flavor and texture

  7. Conceptual design report: Nuclear materials storage facility renovation. Part 3, Supplemental information

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-14

    The Nuclear Materials Storage Facility (NMSF) at the Los Alamos National Laboratory (LANL) was a Fiscal Year (FY) 1984 line-item project completed in 1987 that has never been operated because of major design and construction deficiencies. This renovation project, which will correct those deficiencies and allow operation of the facility, is proposed as an FY 97 line item. The mission of the project is to provide centralized intermediate and long-term storage of special nuclear materials (SNM) associated with defined LANL programmatic missions and to establish a centralized SNM shipping and receiving location for Technical Area (TA)-55 at LANL. Based on current projections, existing storage space for SNM at other locations at LANL will be loaded to capacity by approximately 2002. This will adversely affect LANUs ability to meet its mission requirements in the future. The affected missions include LANL`s weapons research, development, and testing (WRD&T) program; special materials recovery; stockpile survelliance/evaluation; advanced fuels and heat sources development and production; and safe, secure storage of existing nuclear materials inventories. The problem is further exacerbated by LANL`s inability to ship any materials offsite because of the lack of receiver sites for mate rial and regulatory issues. Correction of the current deficiencies and enhancement of the facility will provide centralized storage close to a nuclear materials processing facility. The project will enable long-term, cost-effective storage in a secure environment with reduced radiation exposure to workers, and eliminate potential exposures to the public. It is organized into seven parts. Part I - Design Concept describes the selected solution. Part III - Supplemental Information contains calculations for the various disciplines as well as other supporting information and analyses.

  8. l-glutamine and l-alanine supplementation increase glutamine-glutathione axis and muscle HSP-27 in rats trained using a progressive high-intensity resistance exercise.

    Science.gov (United States)

    Leite, Jaqueline Santos Moreira; Raizel, Raquel; Hypólito, Thaís Menezes; Rosa, Thiago Dos Santos; Cruzat, Vinicius Fernandes; Tirapegui, Julio

    2016-08-01

    In this study we investigated the chronic effects of oral l-glutamine and l-alanine supplementation, either in their free or dipeptide form, on glutamine-glutathione (GLN-GSH) axis and cytoprotection mediated by HSP-27 in rats submitted to resistance exercise (RE). Forty Wistar rats were distributed into 5 groups: sedentary; trained (CTRL); and trained supplemented with l-alanyl-l-glutamine, l-glutamine and l-alanine in their free form (GLN+ALA), or free l-alanine (ALA). All trained animals were submitted to a 6-week ladder-climbing protocol. Supplementations were offered in a 4% drinking water solution for 21 days prior to euthanasia. Plasma glutamine, creatine kinase (CK), myoglobin (MYO), and erythrocyte concentration of reduced GSH and glutathione disulfide (GSSG) were measured. In tibialis anterior skeletal muscle, GLN-GSH axis, thiobarbituric acid reactive substances (TBARS), and the expression of heat shock factor 1 (HSF-1), 27-kDa heat shock protein (HSP-27), and glutamine synthetase were determined. In CRTL animals, high-intensity RE reduced muscle glutamine levels and increased GSSG/GSH rate and TBARS, as well as augmented plasma CK and MYO levels. Conversely, l-glutamine-supplemented animals showed an increase in plasma and muscle levels of glutamine, with a reduction in GSSG/GSH rate, TBARS, and CK. Free l-alanine administration increased plasma glutamine concentration and lowered muscle TBARS. HSF-1 and HSP-27 were high in all supplemented groups when compared with CTRL (p alanine, in both a free or dipeptide form, improve the GLN-GSH axis and promote cytoprotective effects in rats submitted to high-intensity RE training.

  9. 40 CFR 63.4910 - What notifications must I submit?

    Science.gov (United States)

    2010-07-01

    ..., accuracy, and completeness of the report. Such certifications must also comply with the requirements of 40... need to submit copies of any test reports. (i) Mass fraction of organic HAP for one coating, for one... mass of organic HAP contained in the waste materials for which you are claiming an allowance in...

  10. Federal policies to promote the widespread utilization of photovoltaic systems. Supplement: review and critique

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.L.

    1980-04-15

    This document is intended as a supplement to the two-volume report entitled Federal Policies to Promote the Widespread Utilization of Photovoltaic Systems that was submitted to Congress by the Department of Energy in February and April of 1980. This supplement contains review comments prepared by knowledgeable experts who reviewed early drafts of the Congressional report. Responses to the review comments by the Jet Propulsion Laboratory, preparer of the Congressional report, are also included in this supplement. The Congressional report, mandated in the Solar Photovoltaic Energy Research, Development, and Demonstration Act of 1978 (P.L. 95-590), discusses various issues related to promoting the deployment of photovoltaic systems through the Federal Photovoltaic Program. Various program strategies and funding levels are examined.

  11. Safety Evaluation Report related to the operation of Fermi-2 (Docket No. 50-341). Supplement No. 6

    International Nuclear Information System (INIS)

    1985-07-01

    Supplement No. 6 to the Safety Evaluation Report (SER) related to the operation of the Fermi-2 facility, provides the NRC staff's evaluation of additional information submitted by the licensee regarding outstanding review issues identified in Supplement No. 5 to the SER dated March 1985 and also contains the staff's evaluation of the Independent Design Verification Program. Supplement No. 6 to the SER also summarizes the conditions which are placed in the Fermi-2 full-power operating license, NPF-43, and evaluates recent proposed changes to the Fermi-2 Technical Specifications. This supplement presents the staff's conclusion that there are no outstanding issues which must be resolved prior to issuance of a full power operating license for the Fermi-2 facility

  12. BIBLIOGRAPHY ON ACHIEVEMENT. SUPPLEMENT I.

    Science.gov (United States)

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY SUPPLEMENT LISTS MATERIALS ON VARIOUS ASPECTS OF ACHIEVEMENT. APPROXIMATELY 60 REFERENCES ARE PROVIDED TO DOCUMENTS DATING FROM 1961 TO 1966. JOURNALS, BOOKS, AND REPORT MATERIALS ARE LISTED. SUBJECT AREAS INCLUDED ARE ACHIEVEMENT LEVEL, ACADEMIC ACHIEVEMENT, ACHIEVEMENT MOTIVATION, UNDERACHIEVERS, PROBABILITY ESTIMATES, AND…

  13. Issues in Nutrition: Dietary Supplements.

    Science.gov (United States)

    Thompson, Margaret E; Noel, Mary Barth

    2017-01-01

    The majority of American adults report use of one or more dietary supplements every day or occasionally. The Dietary Supplement Health and Education Act of 1994 defines dietary supplements and regulates their manufacture and distribution. One of the most commonly used supplements is vitamin D. Measurement of serum levels of vitamin D must be undertaken with the caveats that different laboratories define normal levels differently, and that there is rarely a clinical correlation with the actual level. Patients should understand that supplements should not be used to excess, as there are toxicities and other adverse effects associated with most of them. There currently is considerable research being performed on probiotics and how the gut microbiome affects health and disease states. Protein supplements may be useful in reducing mortality rates in elderly patients but they do not appear to increase quality of life. If used, protein supplements should contain essential amino acids. Casein and whey supplements, derived from dairy sources, help transport essential amino acids to tissues. Although there have been many studies investigating the role of vitamin supplements in disease prevention, there have been few conclusive positive results. Written permission from the American Academy of Family Physicians is required for reproduction of this material in whole or in part in any form or medium.

  14. Lead in calcium supplements (abstract)

    International Nuclear Information System (INIS)

    Rehman, S.; Khalid, N.

    2011-01-01

    Lead present in calcium supplements is of grave concern as some lead levels have been measured up to the extent of regulatory limit set by the United States. Calcium supplements inevitably get contaminated with lead as both are naturally occurring elements. Therefore, it is imperative to indicate its level in these supplements in order to create awareness among consumers. In this study, a sophisticated analytical technique, atomic absorption spectrometry was used to analyze Pb contents in 27 commonly consumed Ca supplements manufactured by different national and multinational companies. The daily intake of lead through these supplements was calculated. Only 10% of the calcium supplements analyzed met the criteria of acceptable Pb levels (1.5 mu g/daily dose) in supplements/consumer products set by the United States. It was also found that Pb intake was highest in chelated calcium supplements 28.5 mu g/daily dose, whereas lowest 0.47 mu g/daily dose through calcium supplements with vitamin D formulation. In order to validate our results from the study conducted, IAEA-certified reference material (animal bone, H-5) was analyzed for its Pb levels. The levels of Pb determined were quite in good agreement with the certified values. (author)

  15. Efeito da suplementação com L-alanil-L-glutamina sobre a resposta de hipersensibilidade do tipo tardio em ratos submetidos ao treinamento intenso Effect of L-glutamine and L-alanyl-L-glutamine supplementation on the response to delayed-type hypersensitivity test (DTH in rats submitted to intense training

    Directory of Open Access Journals (Sweden)

    Marcelo Macedo Rogero

    2002-12-01

    Full Text Available O treinamento intenso e o exercício exaustivo podem ocasionar imunossupressão em atletas por meio da diminuição da concentração plasmática de glutamina. O presente estudo verificou inicialmente o efeito da suplementação com L-glutamina e L-alanilL-glutamina sobre a resposta ao teste de hipersensibilidade do tipo tardio (HTT em ratos submetidos ao treinamento intenso em natação durante seis semanas. Posteriormente, foi avaliado o efeito dessas intervenções nutricionais sobre a contagem total e porcentual de leucócitos e concentração sérica de anticorpos IgG anti-albumina de soro bovino, em animais submetidos ao teste de exaustão e recuperados durante o período de 3 horas. Não houve efeito do treinamento e da suplementação sobre a resposta ao teste de HTT. Animais suplementados apresentaram maior concentração de glutamina no plasma (PIntense training and exhaustive exercise may cause immunesupression in athletes by reducing plasma glutamine concentration. Initially, this study verified the effect of L-glutamine and L-alanyl-L-glutamine supplementation on the response to delayed-type hypersensitivity test (DTH in rats submitted to intense swimming training for six weeks. Later on, we assessed the effect of these nutritional interventions on total and differential white blood cell counts and on concentration of anti-bovine serum albumin IgG antibodies, in animals submitted to exhaustion test and a three-hour recovery period. There was no effect of training and supplementation on the response to DTH. Supplemented animals presented greatest plasma glutamine concentration (p<0.05, though this increase in glutaminemia did not interfere on the serum IgG antibody concentration. The recovery period after intense exercise resulted in decreased glutaminemia as compared with the values obtained immediately after exhaustion test (p<0.05. Increase in corticosterone levels induced by strenuous exercises led to leukocytosis, neutrophilia

  16. CHILD DEVELOPMENT BIBLIOGRAPHY. SUPPLEMENT I.

    Science.gov (United States)

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY SUPPLEMENT LISTS MATERIAL ON VARIOUS ASPECTS OF CHILD DEVELOPMENT. APPROXIMATELY 90 UNANNOTATED REFERENCES ARE PROVIDED TO DOCUMENTS DATING FROM 1956 TO 1966. JOURNALS, BOOKS, AND REPORT MATERIALS ARE LISTED. SUBJECT AREAS INCLUDED ARE BEHAVIOR TESTS, CONDITIONING, MATERNAL REACTIONS, GRADE PREDICTABILITY, EXPERIMENTAL STUDIES,…

  17. 39 CFR 3007.10 - Submission of non-public materials under seal.

    Science.gov (United States)

    2010-07-01

    ...-public materials shall submit two copies consisting, where practicable, of two paper hard copies as well... available PC application. Each page of any paper hard copy non-public materials submitted shall be clearly... submitted in a searchable electronic format, but need not be submitted in its native format. As part of its...

  18. Exercise x BCAA Supplementation in Young Trained Rats: What are their Effects on Body Growth?

    Science.gov (United States)

    de Campos-Ferraz, Patricia Lopes; Ribeiro, Sandra Maria Lima; Luz, Silmara Dos Santos; Lancha, Antonio Herbert; Tirapegui, Julio

    2011-01-01

    The purpose of this study was to evaluate whether Branched-chain amino acids (BCAAs) supplementation had any beneficial effects on growth and metabolic parameters of young rats submitted to chronic aerobic exercise. Thirty-two young rats (age: 21-d) were randomly assigned to four experimental groups (n = 8): Supplemented Trained (Sup/Ex), Control Trained (Ctrl/Ex), Supplemented Sedentary (Sup/Sed) and Control Sedentary (Ctrl/Sed). The trained groups underwent a five-week swimming protocol and received supplemented (45 mg BCAA/body weight/day) or control ration. Trained animals presented a lower body length and a higher cartilage weight, regardless of supplementation. Physical activity was responsible for a substantial reduction in proteoglycan synthesis in cartilage tissue, and BCAA supplementation was able to attenuate this reduction and also to improve glycogen stores in the liver, although no major differences were found in body growth associated to this supplementation. Key pointsCartilage proteoglycan synthesis was dramatically reduced in trained animals as a whole.BCAA supplementation augmented liver glycogen stores and reduced proteolysis in our experimental conditionsTrained animals receiving BCAA supplementation featured increased proteoglycan synthesis compared to sedentary ones, probably because BCAA may have attenuated the negative effects of exercise on cartilage development.BCAA supplementation was not capable of neutralizing directly the negative effects of long-term physical training and lower food intake in young male rats on body growth.

  19. Safety Evaluation Report related to the operation of Waterford Steam Electric Station, Unit No. 3 (Docket No. 50-382). Supplement No. 8

    International Nuclear Information System (INIS)

    1984-12-01

    Supplement 8 to the Safety Evaluation Report for the application filed by Louisiana Power and Light Company for a license to operate the Waterford Steam Electric Station, Unit 3 (Docket No. 50-382), located in St. Charles Parish, Louisiana, has been prepared by the Office of Nuclear Reactor Regulation of the Nuclear Regulatory Commission. The purpose of this supplement is to update the Safety Evaluation Report by providing the staff's evaluation of information submitted by the applicant since the Safety Evaluation Report and its seven previous supplements were issued

  20. Safety Evaluation Report related to the operation of Palo Verde Nuclear Generating Station, Units 1, 2, and 3 (Docket Nos. STN 50-528, STN 50-529, and STN 50-530). Supplement No. 8

    International Nuclear Information System (INIS)

    1985-05-01

    Purpose of this supplement is to update the Safety Evaluation Report by providing an evaluation of additional information submitted by the applicant since Supplement No. 7 was issued and matters that the staff had under review when Supplement No. 7 was issued, specifically those issues which required resolution prior to plant operation of Unit 1 above 5% full power

  1. Safety evaluation report related to the operation of Watts Bar Nuclear Plant, Units 1 and 2 (Docket Nos. 50-390 and 50-391). Supplement No. 14

    Energy Technology Data Exchange (ETDEWEB)

    Tam, P.S.

    1994-12-01

    Supplement No. 14 to the Safety Evaluation Report for the application filed by the Tennessee Valley Authority for license to operate Watts Bar Nuclear Plant, Units 1 and 2, Docket Nos. 50-390 and 50-391, located in Rhea County, Tennessee, has been prepared by the Office of Nuclear Reactor Regulation of the Nuclear Regulatory Commission. The purpose of this supplement is to update the Safety Evaluation with additional information submitted by the applicant since Supplement No. 13 was issued, and matters that the staff had under review when Supplement No. 13 was issued.

  2. Information to be submitted in support of licensing applications for nuclear power plants

    International Nuclear Information System (INIS)

    1979-01-01

    This Safety Guide was prepared as part of the Agency's programme, referred to as the NUSS programme, for establishing Codes of Practice and Safety Guides relating to nuclear power plants. It supplements the Agency's Safety Series No.50-C-G, entitled ''Governmental Organization for the Regulation of Nuclear Power Plants: A Code of Practice''. It is concerned with the content of documents which should be submitted to the regulatory body by the applicant/licensee in support of licensing applications, with a possible method of classifying these documents and with the scheduling of their submission to the regulatory body at each major stage of the licensing process

  3. Regulations for the safe transport of radioactive material. 1985 ed. Supplement 1986

    International Nuclear Information System (INIS)

    1986-01-01

    Following a six-year effort, a major revision to the Agency's Regulations for the Safe Transport of Radioactive Material (Safety Series No. 6) was issued in 1985. In order to address minor problems with the 1985 Edition of Safety Series No. 6, a panel of experts convened by the International Atomic Energy Agency met from 13 to 17 January 1986. This panel considered minor inconsistencies, omissions or errors that had occurred in the course of preparing the 1985 Edition of Safety Series No. 6, and recommended that two types of change be made. First, changes which will correct errors in the presentation of the text, translation errors (in the French, Russian and Spanish versions of the 1985 Edition), and drafting which failed to express the intent of the panels which reviewed the previous edition of the Regulations; these minor changes are promulgated herewith by the authority of the Director General. Secondly, changes of detail which can only be introduced in accordance with the procedure approved by the Board of Governors on 22 September 1972, which authorizes the Director General to promulgate such changes after giving Governments not less than ninety days' notice and taking into account any comments that they make. Three changes of this second type were recommended by the panel, and were circulated according to the 'ninety-day rule' amendment procedure on 3 February 1986. Those changes which received unanimous support by Member States are included in this Supplement. Corrected text to the 1985 Edition of Safety Series No. 6 (paragraphs, tables, etc.) is provided in this Supplement, and this corrected text supersedes the corresponding portions of the 1985 Edition of Safety Series No. 6.

  4. Plagiarism in submitted manuscripts: incidence, characteristics and optimization of screening-case study in a major specialty medical journal.

    Science.gov (United States)

    Higgins, Janet R; Lin, Feng-Chang; Evans, James P

    2016-01-01

    Plagiarism is common and threatens the integrity of the scientific literature. However, its detection is time consuming and difficult, presenting challenges to editors and publishers who are entrusted with ensuring the integrity of published literature. In this study, the extent of plagiarism in manuscripts submitted to a major specialty medical journal was documented. We manually curated submitted manuscripts and deemed an article contained plagiarism if one sentence had 80 % of the words copied from another published paper. Commercial plagiarism detection software was utilized and its use was optimized. In 400 consecutively submitted manuscripts, 17 % of submissions contained unacceptable levels of plagiarized material with 82 % of plagiarized manuscripts submitted from countries where English was not an official language. Using the most commonly employed commercial plagiarism detection software, sensitivity and specificity were studied with regard to the generated plagiarism score. The cutoff score maximizing both sensitivity and specificity was 15 % (sensitivity 84.8 % and specificity 80.5 %). Plagiarism was a common occurrence among manuscripts submitted for publication to a major American specialty medical journal and most manuscripts with plagiarized material were submitted from countries in which English was not an official language. The use of commercial plagiarism detection software can be optimized by selecting a cutoff score that reflects desired sensitivity and specificity.

  5. BIBLIOGRAPHY ON CURRICULUM DEVELOPMENT. SUPPLEMENT I.

    Science.gov (United States)

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY (SUPPLEMENT I) LISTS MATERIALS ON VARIOUS ASPECTS OF CURRICULUM DEVELOPMENT. EIGHTY-TWO UNANNOTATED REFERENCES ARE PROVIDED FOR DOCUMENTS DATING FROM 1961 TO 1966. BOOKS, JOURNALS, REPORT MATERIALS, AND SOME UNPUBLISHED MANUSCRIPTS ARE LISTED IN SUCH AREAS AS EDUCATIONAL GAMES, CURRICULUM CHANGE, CONCEPT DEVELOPMENT, PROGRAM…

  6. Safety evaluation report related to the operation of Watts Bar Nuclear Plant, Units 1 and 2 (Docket Nos. 50-390 and 50-391): Supplement No. 19

    International Nuclear Information System (INIS)

    1995-11-01

    Supplement No. 19 to the Safety Evaluation Report for the application filed by the Tennessee Valley Authority for license to operate Watts Bar Nuclear Plant, Units 1 and 2, Docket Nos. 50-390 and 50-391, located in Rhea County Tennessee, has been prepared by the Office of Nuclear Reactor Regulation of the Nuclear Regulatory Commission. The purpose of this supplement is to update the Safety Evaluation with (1) additional information submitted by the applicant since Supplement No. 18 was issued, and (2) matters that the staff had under review when Supplement No. 18 was issued

  7. Explanatory supplement to the astronomical almanac

    CERN Document Server

    Urban, Sean E

    2013-01-01

    The Explanatory Supplement to the Astronomical Almanac offers explanatory material, supplemental information and detailed descriptions of the computational models and algorithms used to produce The Astronomical Almanac, which is an annual publication prepared jointly by the US Naval Observatory and Her Majesty's Nautical Almanac Office in the UK. Like The Astronomical Almanac, The Explanatory Supplement provides detailed coverage of modern positional astronomy. Chapters are devoted to the celestial and terrestrial reference frames, orbital ephemerides, precession, nutation, Earth rotation, and coordinate transformations. These topics have undergone substantial revisions since the last edition was published. Astronomical positions are intertwined with timescales and relativity in The Astronomical Almanac, so related chapters are provided in The Explanatory Supplement. The Astronomical Almanac also includes information on lunar and solar eclipses, physical ephemerides of solar system bodies, and calendars, so T...

  8. Blood Parameters and Toxicity of Chromium Picolinate Oral Supplementation in Lambs.

    Science.gov (United States)

    Dallago, Bruno Stéfano Lima; Braz, ShélidaVasconcelos; Marçola, Tatiana Guerrero; McManus, Concepta; Caldeira, Denise Ferreira; Campeche, Aline; Gomes, Edgard Franco; Paim, Tiago Prado; Borges, Bárbara Oliveira; Louvandini, Helder

    2015-11-01

    The effects of oral supplementation of chromium picolinate (CrPic) on various blood parameters and their possible toxicity on the liver, kidneys, lungs, heart, and testis were investigated. Twenty-four Santa Inês (SI) lambs were treated with four different concentrations of CrPic (six animals/treatment): placebo, 0.250, 0.375, and 0.500 mg CrPic/animal/day for 84 days. The basal diet consisted of hay Panicum maximum cv Massai and concentrate. Blood and serum were collected fortnightly for analysis. On day 84, the animals were euthanized, and histopathological analysis in the liver, kidney, heart, lung, and testis was made. The liver and kidney were also submitted to electronic microscopy analysis. Differences between treatments (P plasm protein (day 56 and day 84), and triglycerides (day 70). There was no statistically significant relationship between Cr supplementation and histopathology findings, although some animals treated with supplementary Cr showed morphological changes in the liver, kidney, and testis. Thus, the effectiveness of supplementation with Cr remains in doubt as to its physiological action and toxicity in sheep.

  9. Effects of Supplementation with BCAA and L-glutamine on Blood Fatigue Factors and Cytokines in Juvenile Athletes Submitted to Maximal Intensity Rowing Performance.

    Science.gov (United States)

    Koo, Ga Hee; Woo, Jinhee; Kang, Sungwhun; Shin, Ki Ok

    2014-08-01

    [Purpose] This study was conducted to understand the impacts of BCAA (branched-chain amino acid) and glutamine supplementation on the degree of blood fatigue factor stimulation and cytokines along with performance of exercise at the maximal intensity. [Subjects] Five male juvenile elite rowing athletes participated in this study as the subjects; they took 3 tests and received placebo supplementation (PS), BCAA supplementation (BS), and glutamine supplementation (GS). [Methods] The exercise applied in the tests was 2,000 m of rowing at the maximal intensity using an indoor rowing machine, and blood samples were collected 3 times, while resting, at the end of exercise, and after 30 min of recovery, to analyze the blood fatigue factors (lactate, phosphorous, ammonia, creatine kinase (CK)) and blood cytokines (IL (interleukin)-6, 8, 15). [Results] The results of the analysis showed that the levels of blood phosphorous in the BS and GS groups at the recovery stage were decreased significantly compared with at the end of exercise, and the level of CK appeared lower in the GS group alone at recovery stage than at the end of exercise. The level of blood IL-15 in the PS and BS groups appeared higher at the end of exercise compared with the resting stage. [Conclusion] It seemed that glutamine supplementation had a positive effect on the decrease in fatigue factor stimulation at the recovery stage after maximal intensity exercise compared with supplementation with the placebo or BCAA. Besides, pre-exercise glutamine supplementation seemed to help enhance immune function and the defensive inflammatory reaction.

  10. Rectal dose assessment in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer

    International Nuclear Information System (INIS)

    Oliveira, Jetro Pereira de; Batista, Delano Valdivino Santos; Bardella, Lucia Helena; Carvalho, Arnaldo Rangel

    2009-01-01

    Objective: The present study was aimed at developing a thermoluminescent dosimetric system capable of assessing the doses delivered to the rectum of patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. Materials and methods: LiF:Mg,Ti,Na powder was the thermoluminescent material utilized for evaluating the rectal dose. The powder was divided into small portions (34 mg) which were accommodated in a capillary tube. This tube was placed into a rectal probe that was introduced into the patient's rectum. Results: The doses delivered to the rectum of six patients submitted to high-dose-rate brachytherapy for uterine cervix cancer evaluated by means of thermoluminescent dosimeters presented a good agreement with the planned values based on two orthogonal (anteroposterior and lateral) radiographic images of the patients. Conclusion: The thermoluminescent dosimetric system developed in the present study is simple and easy to be utilized as compared to other rectal dosimetry methods. The system has shown to be effective in the evaluation of rectal doses in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. (author)

  11. Dosimetry of patients submitted to cerebral PET/CT for the diagnosis of mild cognitive impairment

    Energy Technology Data Exchange (ETDEWEB)

    Santana, Priscila do Carmo; Oliveira, Paulo Marcio Campos de; Bernardes, Felipe Dias; Mamede, Marcelo, E-mail: pridili@gmail.com [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil); Mourao, Arnaldo Prata [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET), Belo Horizonte, MG (Brazil); Silva, Teogenes Augusto da [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2014-11-15

    Objective: the present study was aimed at evaluating the effective radiation dose in patients submitted to PET/CT for the diagnosis of mild cognitive impairment. Materials and methods: TLD-100 detectors inserted into an Alderson Rando® anthropomorphic phantom were utilized to measure the absorbed dose coming from the CT imaging modality. The anthropomorphic phantoms (male and female adult versions) were submitted to the same technical protocols for patients’ images acquisition. The absorbed dose resulting from the radiopharmaceutical injection was estimated by means of the model proposed by the ICRP publication 106. Results: the effective dose in patients submitted to this diagnostic technique was approximately (5.34 ± 1.99) mSv. Conclusion: optimized protocols for calculation of radioactive activity injected into patients submitted to this diagnostic technique might contribute to reduce the effective radiation dose resulting from PET/CT in the diagnosis of mild cognitive impairment. (author)

  12. Dosimetry of patients submitted to cerebral PET/CT for the diagnosis of mild cognitive impairment

    International Nuclear Information System (INIS)

    Santana, Priscila do Carmo; Oliveira, Paulo Marcio Campos de; Bernardes, Felipe Dias; Mamede, Marcelo; Mourao, Arnaldo Prata; Silva, Teogenes Augusto da

    2014-01-01

    Objective: the present study was aimed at evaluating the effective radiation dose in patients submitted to PET/CT for the diagnosis of mild cognitive impairment. Materials and methods: TLD-100 detectors inserted into an Alderson Rando® anthropomorphic phantom were utilized to measure the absorbed dose coming from the CT imaging modality. The anthropomorphic phantoms (male and female adult versions) were submitted to the same technical protocols for patients’ images acquisition. The absorbed dose resulting from the radiopharmaceutical injection was estimated by means of the model proposed by the ICRP publication 106. Results: the effective dose in patients submitted to this diagnostic technique was approximately (5.34 ± 1.99) mSv. Conclusion: optimized protocols for calculation of radioactive activity injected into patients submitted to this diagnostic technique might contribute to reduce the effective radiation dose resulting from PET/CT in the diagnosis of mild cognitive impairment. (author)

  13. Waste characterization emanated from kaolin submitted the improvement to process hydrocycloning

    International Nuclear Information System (INIS)

    Barbosa Neto, M.C.; Nunes, A.S.; Caetano, A.L.A.; Marques, V.C.; Macedo, D.A.; Ferreira, H.S.; Dutra, R.P.S.

    2016-01-01

    The hydrocyclones are equipment commonly used for separation of particles by size. The resulting material of this process usually presents different characteristics of the material, which was not subjected to treatment. Therefore, a study of the waste characteristics derived from kaolin processing submitted to hydrocycloning process compared to the same residue without going through the process was executed. The different samples were characterized by X-ray diffraction, X-ray fluorescence, particle size analysis and thermal analysis. The results indicate that the hydrocycloning not modify the mineralogical structure nor chemical material. The particle size analysis identified that the fine fraction, resulting from the process, presented particle size lower than the reference material. (author)

  14. Radioactivity survey of 'health foods' (supplements) marketed in Japan

    International Nuclear Information System (INIS)

    Miyake, Sadaaki; Yoshida, Terumitsu; Takahashi, Kunihiko; Iijima, Masao; Urabe, Ken-ichi

    2010-01-01

    Concentrations of 134 Cs, 137 Cs and 40 K in 73 supplements marked in Japan were measured by gamma-ray spectrometry. In all supplements, 134 Cs was not detected. On the other hand, 134 Cs was detected in 9 supplements, and the concentrations of 137 Cs in them were in the range of 2.3-190 Bq/kg. There was a tendency that concentrations of 137 Cs in supplements made from materials accumulating 137 Cs, such as mushrooms and blueberries, were high. Furthermore, 40 K was detected in 56 supplements at levels of 17.6-11600 Bq/kg. The committed effective dose of 137 Cs in adults by annually taking supplements was estimated to be about 2.9 μSv. (author)

  15. Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary Supplements

    Science.gov (United States)

    Dwyer, Johanna T.; Picciano, Mary Frances; Betz, Joseph M.; Fisher, Kenneth D.; Saldanha, Leila G.; Yetley, Elizabeth A.; Coates, Paul M.; Milner, John A.; Whitted, Jackie; Burt, Vicki; Radimer, Kathy; Wilger, Jaimie; Sharpless, Katherine E.; Holden, Joanne M.; Andrews, Karen; Roseland, Janet; Zhao, Cuiwei; Schweitzer, Amy; Harnly, James; Wolf, Wayne R.; Perry, Charles R.

    2013-01-01

    Although an estimated 50% of adults in the United States consume dietary supplements, analytically substantiated data on their bioactive constituents are sparse. Several programs funded by the Office of Dietary Supplements (ODS) at the National Institutes of Health enhance dietary supplement database development and help to better describe the quantitative and qualitative contributions of dietary supplements to total dietary intakes. ODS, in collaboration with the United States Department of Agriculture, is developing a Dietary Supplement Ingredient Database (DSID) verified by chemical analysis. The products chosen initially for analytical verification are adult multivitamin-mineral supplements (MVMs). These products are widely used, analytical methods are available for determining key constituents, and a certified reference material is in development. Also MVMs have no standard scientific, regulatory, or marketplace definitions and have widely varying compositions, characteristics, and bioavailability. Furthermore, the extent to which actual amounts of vitamins and minerals in a product deviate from label values is not known. Ultimately, DSID will prove useful to professionals in permitting more accurate estimation of the contribution of dietary supplements to total dietary intakes of nutrients and better evaluation of the role of dietary supplements in promoting health and well-being. ODS is also collaborating with the National Center for Health Statistics to enhance the National Health and Nutrition Examination Survey dietary supplement label database. The newest ODS effort explores the feasibility and practicality of developing a database of all dietary supplement labels marketed in the US. This article describes these and supporting projects. PMID:25346570

  16. Meeting Local Needs in Materials Writing

    Directory of Open Access Journals (Sweden)

    Rahma Al-Mahrooqi

    2010-01-01

    Full Text Available Textbooks are viewed as an essential tool in ELT. Despite the abundance of commercial textbooks, very few of them seem to meet the local needs of students and teachers in a certain context, owing to certain pitfalls in the materials. When a program adopts a certain commercial textbook the teachers soon realize that they have to supplement the materials to bridge the gap between what these materials offer and the local needs. Sometimes the supplementation yields greater volumes of materials than the book itself, causing teachers and learners to lose focus. An added complexity is the fact that there are always new, more attractive titles in the market, leaving the program in a dilemma of whether to keep their old, well supplemented textbooks or to replace them with new ones and start another cycle of supplementation. The ideal solution is for a program to produce its own teaching materials. However, writing quality local materials that can compete with commercial ones can be a real challenge. It requires clear vision, creativity, commitment and team work.

  17. BIBLIOGRAPHY ON THE CULTURALLY DISADVANTAGED. SUPPLEMENT III.

    Science.gov (United States)

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY SUPPLEMENT LISTS MATERIAL ON VARIOUS ASPECTS OF THE CULTURALLY DISADVANTAGED. APPROXIMATELY 220 UNANNOTATED REFERENCES ARE PROVIDED TO DOCUMENTS DATING FROM 1963 TO 1966. JOURNALS, BOOKS, AND REPORT MATERIALS ARE LISTED. SUBJECT AREAS INCLUDED ARE PRESCHOOL PROGRAMS, NEIGHBORHOOD DEVELOPMENT PROGRAMS, SHORT-TERM GROUP COUNSELING,…

  18. Authentication of Herbal Supplements Using Next-Generation Sequencing.

    Directory of Open Access Journals (Sweden)

    Natalia V Ivanova

    Full Text Available DNA-based testing has been gaining acceptance as a tool for authentication of a wide range of food products; however, its applicability for testing of herbal supplements remains contentious.We utilized Sanger and Next-Generation Sequencing (NGS for taxonomic authentication of fifteen herbal supplements representing three different producers from five medicinal plants: Echinacea purpurea, Valeriana officinalis, Ginkgo biloba, Hypericum perforatum and Trigonella foenum-graecum. Experimental design included three modifications of DNA extraction, two lysate dilutions, Internal Amplification Control, and multiple negative controls to exclude background contamination. Ginkgo supplements were also analyzed using HPLC-MS for the presence of active medicinal components.All supplements yielded DNA from multiple species, rendering Sanger sequencing results for rbcL and ITS2 regions either uninterpretable or non-reproducible between the experimental replicates. Overall, DNA from the manufacturer-listed medicinal plants was successfully detected in seven out of eight dry herb form supplements; however, low or poor DNA recovery due to degradation was observed in most plant extracts (none detected by Sanger; three out of seven-by NGS. NGS also revealed a diverse community of fungi, known to be associated with live plant material and/or the fermentation process used in the production of plant extracts. HPLC-MS testing demonstrated that Ginkgo supplements with degraded DNA contained ten key medicinal components.Quality control of herbal supplements should utilize a synergetic approach targeting both DNA and bioactive components, especially for standardized extracts with degraded DNA. The NGS workflow developed in this study enables reliable detection of plant and fungal DNA and can be utilized by manufacturers for quality assurance of raw plant materials, contamination control during the production process, and the final product. Interpretation of results should

  19. Authentication of Herbal Supplements Using Next-Generation Sequencing.

    Science.gov (United States)

    Ivanova, Natalia V; Kuzmina, Maria L; Braukmann, Thomas W A; Borisenko, Alex V; Zakharov, Evgeny V

    2016-01-01

    DNA-based testing has been gaining acceptance as a tool for authentication of a wide range of food products; however, its applicability for testing of herbal supplements remains contentious. We utilized Sanger and Next-Generation Sequencing (NGS) for taxonomic authentication of fifteen herbal supplements representing three different producers from five medicinal plants: Echinacea purpurea, Valeriana officinalis, Ginkgo biloba, Hypericum perforatum and Trigonella foenum-graecum. Experimental design included three modifications of DNA extraction, two lysate dilutions, Internal Amplification Control, and multiple negative controls to exclude background contamination. Ginkgo supplements were also analyzed using HPLC-MS for the presence of active medicinal components. All supplements yielded DNA from multiple species, rendering Sanger sequencing results for rbcL and ITS2 regions either uninterpretable or non-reproducible between the experimental replicates. Overall, DNA from the manufacturer-listed medicinal plants was successfully detected in seven out of eight dry herb form supplements; however, low or poor DNA recovery due to degradation was observed in most plant extracts (none detected by Sanger; three out of seven-by NGS). NGS also revealed a diverse community of fungi, known to be associated with live plant material and/or the fermentation process used in the production of plant extracts. HPLC-MS testing demonstrated that Ginkgo supplements with degraded DNA contained ten key medicinal components. Quality control of herbal supplements should utilize a synergetic approach targeting both DNA and bioactive components, especially for standardized extracts with degraded DNA. The NGS workflow developed in this study enables reliable detection of plant and fungal DNA and can be utilized by manufacturers for quality assurance of raw plant materials, contamination control during the production process, and the final product. Interpretation of results should involve an

  20. L-arginine and glycine supplementation in the repair of the irradiated colonic wall of rats.

    Science.gov (United States)

    de Aguiar Picanço, Etiene; Lopes-Paulo, Francisco; Marques, Ruy G; Diestel, Cristina F; Caetano, Carlos Eduardo R; de Souza, Mônica Vieira Mano; Moscoso, Gabriela Mendes; Pazos, Helena Maria F

    2011-05-01

    Radiotherapy is widely used for cancer treatment but has harmful effects. This study aimed to assess the effects of L-arginine and glycine supplementation on the colon wall of rats submitted to abdominal irradiation. Forty male Wistar rats were randomly divided into four groups: I-healthy, II-irradiated with no amino acid supplementation, III-irradiated and supplemented with L-arginine, and IV-irradiated and supplemented with glycine. The animals received supplementation for 14 days, with irradiation being applied on the eighth day of the experiment. All animals underwent laparotomy on the 15th day for resection of a colonic segment for stereologic analysis. Parametric and nonparametric tests were used for statistical analysis, with the level of significance set at p ≤0.05. Stereologic analysis showed that irradiation induced a reduction of the total volume of the colon wall of group II and III animals compared to healthy controls, but not of group IV animals supplemented with glycine. The mucosal layer of the irradiated animals of all groups was reduced compared to healthy group I animals, but supplementation with L-arginine and glycine was effective in maintaining the epithelial surface of the mucosal layer. The present results suggest that glycine supplementation had a superior effect on the irradiated colon wall compared to L-arginine supplementation since it was able to maintain the thickness of the wall and the epithelial surface of the mucosa, whereas L-arginine maintained the partial volume of the epithelium and the epithelial surface, but not the total volume of the intestinal wall.

  1. Supplementary Material for: Detection of antibiotic resistance in probiotics of dietary supplements

    KAUST Repository

    Wong, Aloysius Tze

    2015-01-01

    Abstract Background Probiotics are live microorganisms that confer nutrition- and health-promoting benefits if consumed in adequate amounts. Concomitant with the demand for natural approaches to maintaining health is an increase in inclusion of probiotics in food and health products. Since probiotic bacteria act as reservoir for antibiotic resistant determinants, the transfer of these genes to pathogens sharing the same intestinal habitat is thus conceivable considering the fact that dietary supplements contain high amounts of often heterogeneous populations of probiotics. Such events can confer pathogens protection against commonly-used drugs. Despite numerous reports of antibiotic resistant probiotics in food and biological sources, the antibiogram of probiotics from dietary supplements remained elusive. Findings Here, we screened five commercially available dietary supplements for resistance towards antibiotics of different classes. Probiotics of all batches of products were resistant towards vancomycin while batch-dependent resistance towards streptomycin, aztreonam, gentamycin and/or ciprofloxacin antibiotics was detected for probiotics of brands Bi and Bn, Bg, and L. Isolates of brand Cn was also resistant towards gentamycin, streptomycin and ciprofloxacin antibiotics. Additionally, we also report a discrepancy between the enumerated viable bacteria amounts and the claims of the manufacturers. Conclusions This short report has highlighted the present of antibiotic resistance in probiotic bacteria from dietary supplements and therefore serves as a platform for further screenings and for in-depth characterization of the resistant determinants and the molecular machinery that confers the resistance.

  2. Perchlorate, iodine supplements, iodized salt and breast milk iodine content

    Energy Technology Data Exchange (ETDEWEB)

    Kirk, Andrea B. [Department of Epidemiology, School of Public Health, University of North Texas Health Sciences Center, 3500 Camp Bowie Blvd., Fort Worth, TX 76107 (United States); Kroll, Martina; Dyke, Jason V.; Ohira, Shin-Ichi; Dias, Rukshan A.; Dasgupta, Purnendu K. [Department of Chemistry and Biochemistry, 700 Planetarium Place, University of Texas at Arlington, Arlington, TX 76019 (United States)

    2012-03-15

    This study was undertaken to determine if increasing maternal iodine intake through single dose tablets will decrease breast milk concentrations of the iodine-uptake inhibitor, perchlorate, through competitive inhibition. We also sought to determine if the timing of supplementation influences the fraction of iodine excreted in milk versus urine and to compare the effectiveness of iodized salt as a means of providing iodine to breastfed infants. Thirteen women who did not use supplements, seven of whom used iodized salt and six of whom used non-iodized salt, submitted four milk samples and a 24-h urine collection daily for three days. Women repeated the sampling protocol for three more days during which {approx} 150 {mu}g of iodine were taken in the evening and again for three days with morning supplementation. Samples were analyzed using isotope-dilution inductively-coupled plasma-mass spectrometry for iodine and isotope-dilution ion chromatography-tandem mass spectrometry for perchlorate. No statistically significant differences were observed in milk iodine or perchlorate concentrations during the two treatment periods. Estimated perchlorate intake was above the U.S. National Academy of Sciences suggested reference dose for most infants. Single daily dose iodine supplementation was not effective in decreasing milk perchlorate concentrations. Users of iodized salt had significantly higher iodine levels in milk than non-users. Iodized salt may be a more effective means of iodine supplementation than tablets. - Highlights: Black-Right-Pointing-Pointer Estimated infant exposures to perchlorate were, on a {mu}g/kg basis, {approx} 5 Multiplication-Sign higher than those of mothers. Black-Right-Pointing-Pointer Daily supplements are less effective than iodized salt in providing iodine to lactating women. Black-Right-Pointing-Pointer Low iodine and high perchlorate in milk may place infants at risk of iodine deficiency.

  3. Regeneration of the intestinal mucosa in Eimeria and E. Coli challenged broilers supplemented with amino acids.

    Science.gov (United States)

    Gottardo, E T; Prokoski, K; Horn, D; Viott, A D; Santos, T C; Fernandes, J I M

    2016-05-01

    The aim of this study was to evaluate the regeneration of the intestinal mucosa in Eimeria and E. coli challenged broilers supplemented with glutamine, arginine, and threonine. Six hundred male broilers at one d of age from the Cobb strain were utilized. The design was completely randomized using a 2×3 factorial design (unchallenged and challenged and 3 diets). A commercial diet was used as a control and 2 other diets were formulated with glutamine (1.5 and 3% Aminogut®), arginine (1 and 2% L-Arginine), and threonine (1 and 2% L-threonine). The animals that consumed diets supplemented with amino acids presented better (Pbroilers that received diets supplemented with amino acids. High levels of amino acids in the experimental feeds reflected in greater protein levels in poultry house litter, and they did not interfere with ammonia production. The supplementation of diets with trophic amino acids can positively contribute to the regeneration and proliferation of the intestinal mucosa in broilers and to the maintenance of zootechnical performance when submitted to enteric challenges. © 2016 Poultry Science Association Inc.

  4. Supplemental Material, PWQ42_2_747845_Choma_and_Prusaczyk - The Effects of System Justifying Beliefs on Skin-Tone Surveillance, Skin-Color Dissatisfaction, and Skin-Bleaching Behavior

    OpenAIRE

    Choma, Becky L.; Prusaczyk, Elvira

    2018-01-01

    Supplemental Material, PWQ42_2_747845_Choma_and_Prusaczyk for The Effects of System Justifying Beliefs on Skin-Tone Surveillance, Skin-Color Dissatisfaction, and Skin-Bleaching Behavior by Becky L. Choma, and Elvira Prusaczyk in Psychology of Women Quarterly

  5. Materials in Participatory Design Processes

    DEFF Research Database (Denmark)

    Hansen, Nicolai Brodersen

    This dissertation presents three years of academic inquiry into the question of what role materials play in interaction design and participatory design processes. The dissertation aims at developing conceptual tools, based on Deweys pragmatism, for understanding how materials aid design reflection....... It has been developed using a research-through-design approach in which the author has conducted practical design work in order to investigate and experiment with using materials to scaffold design inquiry. The results of the PhD work is submitted as seven separate papers, submitted to esteemed journals...... and conferences within the field of interaction design and HCI. The work is motivated both by the growing interest in materials in interaction design and HCI and the interest in design processes and collaboration within those fields. At the core of the dissertation lies an interest in the many different materials...

  6. Closeout of NRC Bulletin 88-05: Nonconforming materials supplied by Piping Supplies, Inc., at Folsom, New Jersey, and West Jersey Manufacturing Company at Williamstown, New Jersey

    International Nuclear Information System (INIS)

    1990-05-01

    This report documents the activities that led to the closeout of U.S. Nuclear Regulatory Commission (NRC) Bulletin 88-05, which was issued on May 6, 1988. The bulletin required that licensees submit information on materials supplied by Piping Supplies, Inc. (PSI) and West Jersey Manufacturing Company (WJM), and requested that they (1) ensure that these materials complied with the American Society of Mechanical Engineers, Boiler and Pressure Vessel Code (ASME Code) and design specifications or were suitable for their intended service or (2) replace such materials. Supplements 1 and 2 were issued on June 15 and August 3, 1988, respectively. In Supplement 2, another affiliated supplier, Chews Landing Metal Manufacturers, Incorporated (CLM), was identified. The staff concluded that (1) the analytical procedures used to qualify the nonconforming parts and the analysis results provide and adequate basis for resolving the staff's concerns regarding fitting and flanges; (2) even though the materials supplied by PSI, WJM, and CLM with falsified certified material test reports do not meet the ASME Code, their use is an acceptable alternative in accordance with Section 50.55a(a)(3)(ii) of Title 10 of the Code of Federal Regulations; (3) activities in response to Bulletin 88-05 regarding fittings and flanges can be closed for all operating plants; and (4) licensees should evaluate the use of product forms other fittings and flanges

  7. 75 FR 36120 - Proposed Information Collection Request Submitted for Public Comment and Recommendations; Program...

    Science.gov (United States)

    2010-06-24

    ... Submitted for Public Comment and Recommendations; Program To Prevent Smoking Underground and in Hazardous... mine operators are required to develop programs to prevent persons from carrying smoking materials, matches, or lighters underground and to prevent smoking in hazardous areas, such as in or around oil...

  8. Probiotic supplements and debridement of peri-implant mucositis

    DEFF Research Database (Denmark)

    Hallström, Hadar; Lindgren, Susann; Widén, Cecilia

    2016-01-01

    OBJECTIVE: The aim of this double-blind randomized placebo-controlled trial was to evaluate the effects of probiotic supplements in adjunct to conventional management of peri-implant mucositis. MATERIALS AND METHODS: Forty-nine adult patients with peri-implant mucositis were consecutively recruited...... debridement and oral hygiene reinforcement resulted in clinical improvement of peri-implant mucositis and a reduction in cytokine levels. Probiotic supplements did not provide added benefit to placebo....

  9. Evaluation of the Structural Safety of a Vessel with Different Material(Cr-13)-Supplemented Screw Thread

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yong Hoon; Bae, Jun Ho; Kim, Chul [Pusan National University, Busan (Korea, Republic of)

    2015-04-15

    The dome and neck part of a vessel is generally formed by a hot spinning process with a seamless tube. However, as studies on and design data from the hot spinning process are insufficient, this process has been performed based on trial and error and the experiences of field engineers. Changes in the inner diameter from the bottom to the top of the neck have occurred mainly because of the characteristics of the hot spinning process due to the high-speed rotation of the rollers. In this study, a theoretical and finite element analysis of the vessel is conducted with different material(Cr-13)-supplemented screw threads for tapping and to reduce shape errors. Based on the results, the structural safety under the operating conditions is evaluated.

  10. Chromatic stability of acrylic resins of artificial eyes submitted to accelerated aging and polishing.

    Science.gov (United States)

    Goiato, Marcelo Coelho; Santos, Daniela Micheline dos; Souza, Josiene Firmino; Moreno, Amália; Pesqueira, Aldiéris Alves

    2010-12-01

    Esthetics and durability of materials used to fabricate artificial eyes has been an important issue since artificial eyes are essential to restore esthetics and function, protect the remaining tissues and help with patients' psychological therapy. However, these materials are submitted to degrading effects of environmental agents on the physical properties of the acrylic resin. This study assessed the color stability of acrylic resins used to fabricate sclera in three basic shades (N1, N2 and N3) when subjected to accelerated aging, mechanical and chemical polishing. Specimens of each resin were fabricated and submitted to mechanical and chemical polishing. Chromatic analysis was performed before and after accelerated aging through ultraviolet reflection spectrophotometry. All specimens revealed color alteration following polishing and accelerated aging. The resins presented statistically significant chromatic alteration (p<0.01) between the periods of 252 and 1008 h. Both polishing methods presented no significant difference between the values of color derivatives of resins.

  11. Compost supplementation with nutrients and microorganisms in composting process.

    Science.gov (United States)

    Sánchez, Óscar J; Ospina, Diego A; Montoya, Sandra

    2017-11-01

    The composting is an aerobic, microorganism-mediated, solid-state fermentation process by which different organic materials are transformed into more stable compounds. The product obtained is the compost, which contributes to the improvement of physical, chemical and microbiological properties of the soil. However, the compost usage in agriculture is constrained because of its long-time action and reduced supply of nutrients to the crops. To enhance the content of nutrients assimilable by the plants in the compost, its supplementation with nutrients and inoculation with microorganisms have been proposed. The objective of this work was to review the state of the art on compost supplementation with nutrients and the role played by the microorganisms involved (or added) in their transformation during the composting process. The phases of composting are briefly compiled and different strategies for supplementation are analyzed. The utilization of nitrogenous materials and addition of microorganisms fixing nitrogen from the atmosphere or oxidizing ammonia into more assimilable for plants nitrogenous forms are analyzed. Several strategies for nitrogen conservation during composting are presented as well. The supplementation with phosphorus and utilization of microorganisms solubilizing phosphorus and potassium are also discussed. Main groups of microorganisms relevant during the composting process are described as well as most important strategies to identify them. In general, the development of this type of nutrient-enriched bio-inputs requires research and development not only in the supplementation of compost itself, but also in the isolation and identification of microorganisms and genes allowing the degradation and conversion of nitrogenous substances and materials containing potassium and phosphorus present in the feedstocks undergoing the composting process. In this sense, most important research trends and strategies to increase nutrient content in the compost

  12. Safety Evaluation Report related to the operation of Palo Verde Nuclear Generating Station, Units 1, 2, and 3 (Docket Nos. STN 50-528, STN 50-529, and STN 50-530). Supplement No. 7

    International Nuclear Information System (INIS)

    1984-12-01

    Supplement No. 7 to the Safety Evaluation Report for the application filed by Arizona Public Service Company et al. for licenses to operate the Palo Verde Nuclear Generating Station, Units 1, 2, and 3 (Docket Nos. STN 50-528/529/530), located in Maricopa County, Arizona, has been prepared by the Office of Nuclear Reactor Regulation of the Nuclear Regulatory Commission. The purpose of this supplement is to update the Safety Evaluation Report by providing an evaluation of: (1) additional information submitted by the applicant since Supplement No. 6 was issued; and (2) matters that the staff had under review when Supplement No. 6 was issued

  13. Effect of organic mineral supplementation on the egg quality of semi-heavy layers in their second cycle of lay

    Directory of Open Access Journals (Sweden)

    ESPB Saldanha

    2009-12-01

    Full Text Available This study was carried out to evaluate the effects of dietary trace mineral levels and sources on egg quality parameters of second-cycle semi-heavy layers. A number of 360 72-week-old layers were submitted to forced molting. Upon return of lay (83 weeks of age, birds were distributed according to a completely randomized experimental design of six treatments with six replicates of 10 birds each. The control treatment consisted of 0.10% dietary supplementation of trace minerals from inorganic sources, which was proportionally replaced by five levels (110, 100, 90, 80, 70% of an organic trace mineral supplement containing 30, 30, 40, 6, 0.61, and 0.3 g/kg product of Zn, Fe, Mn, Cu, I, and Se, respectively. All diets contained equal protein, energy, and amino acid levels. Every 28 days of the experimental period (112 days four eggs per replicate were collected for egg quality evaluation. The following parameters were evaluated: specific gravity, yolk, albumen and eggshell percentages, yolk index, Haugh units, and eggshell thickness and breaking strength. One sample per replicate, consisting of the pool of the yolks of three eggs collected at the end of each experimental period, was used to assess protein and mineral (Ca, P, Cu, Fe, Mn, and Zn contents. The results were submitted to ANOVA, and means to the test of Tukey at 5% significance level. The evaluated trace mineral levels and sources did not influence any of the studied egg quality parameters. It was concluded that reducing organic trace mineral supplementation in up to 70% relative to 100% inorganic trace mineral supplementation does not affect egg parameters and therefore, can be applied to the diet of semi-heavy layers in their second cycle of lay.

  14. Sports Supplements

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Sports Supplements KidsHealth / For Teens / Sports Supplements What's in ... really work? And are they safe? What Are Sports Supplements? Sports supplements (also called ergogenic aids ) are ...

  15. Effects of Diets Supplemented with Branched-Chain Amino Acids on the Performance and Fatigue Mechanisms of Rats Submitted to Prolonged Physical Exercise

    Directory of Open Access Journals (Sweden)

    Inar Alves de Castro

    2012-11-01

    Full Text Available This study aimed to determine the effects of diets chronically supplemented with branched-chain amino acids (BCAA on the fatigue mechanisms of trained rats. Thirty-six adult Wistar rats were trained for six weeks. The training protocol consisted of bouts of swimming exercise (one hour a day, five times a week, for six weeks. The animals received a control diet (C (n = 12, a diet supplemented with 3.57% BCAA (S1 (n = 12, or a diet supplemented with 4.76% BCAA (S2 (n = 12. On the last day of the training protocol, half the animals in each group were sacrificed after one hour of swimming (1H, and the other half after a swimming exhaustion test (EX. Swimming time until exhaustion was increased by 37% in group S1 and reduced by 43% in group S2 compared to group C. Results indicate that the S1 diet had a beneficial effect on performance by sparing glycogen in the soleus muscle (p < 0.05 and by inducing a lower concentration of plasma ammonia, whereas the S2 diet had a negative effect on performance due to hyperammonemia (p < 0.05. The hypothalamic concentration of serotonin was not significantly different between the 1H and EX conditions. In conclusion, chronic BCAA supplementation led to increased performance in rats subjected to a swimming test to exhaustion. However, this is a dose-dependent effect, since chronic ingestion of elevated quantities of BCAA led to a reduction in performance.

  16. 76 FR 76728 - Benefits and Burdens of Requiring Commenters To File Cited Materials in Rulemaking Proceedings as...

    Science.gov (United States)

    2011-12-08

    ... Requiring Commenters To File Cited Materials in Rulemaking Proceedings as Further Reform To Enhance Record... materials they cite in pleadings submitted in rulemaking proceedings, so that those materials are more... should require commenters to file materials they cite in pleadings submitted in rulemaking proceedings...

  17. How to Submit a Risk Management Plan (RMP) to EPA

    Science.gov (United States)

    RMP*eSubmit software is the only way to submit RMPs. After you have prepared your plan using RMP*eSubmit, you may also re-submit, correct, or withdraw an RMP. Another electronic tool, RMP*Comp, performs the required off-site consequence analysis.

  18. USE OF TWO DIGESTION METHODS IN THE EVALUATION OF CHROMIUM CONTENT IN CATTLE'S MEAT SUPPLEMENTED WITH CHROMIUM CHELATES

    Directory of Open Access Journals (Sweden)

    R. L. T. de Andrade

    2015-06-01

    Full Text Available The present study aimed to analyze the chromium content in beef using two digestion methods. There were used samples from 24 18-month-old male cattle, and twelve of them were supplemented and twelve were not supplemented with chromium chelate. These samples were evaluated by atomic absorption spectroscopy, previously submitted to digestion method using nitric acid (65% with hydrogen peroxide (35% and to digestion method, using solution of nitric perchloric acid in the proportion 3:1. Immediately after the slaughter, the carcasses were sent to sanitary maturation. After 24 hours, samples between 12th and 13th rib in the muscle Longissimus Thoracis were taken. For evaluation, it was used completely randomized design (Die and analysis of variance (ANOVA at 5% of significance level. The results didn't evidenced any significant difference (p>0,05 between the (cromo content, regardless the supplementation. The same happened with the digestion methods used.

  19. Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats

    Directory of Open Access Journals (Sweden)

    de Mello Maria

    2002-04-01

    Full Text Available Abstract Background It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal muscle. Methods To evaluate the effects of a leucine supplemented diet on the intestinal absorption alterations produced by Walker 256, growing pregnant rats were distributed into six groups. Three pregnant groups received a normal protein diet (18% protein: pregnant (N, tumor-bearing (WN, pair-fed rats (Np. Three other pregnant groups were fed a diet supplemented with 3% leucine (15% protein plus 3% leucine: leucine (L, tumor-bearing (WL and pair-fed with leucine (Lp. Non pregnant rats (C, which received a normal protein diet, were used as a control group. After 20 days, the animals were submitted to intestinal perfusion to measure leucine, methionine and glucose absorption. Results Tumor-bearing pregnant rats showed impairment in food intake, body weight gain and muscle protein content, which were less accentuated in WL than in WN rats. These metabolic changes led to reduction in both fetal and tumor development. Leucine absorption slightly increased in WN group. In spite of having a significant decrease in leucine and methionine absorption compared to L, the WL group has shown a higher absorption rate of methionine than WN group, probably due to the ingestion of the leucine supplemented diet inducing this amino acid uptake. Glucose absorption was reduced in both tumor-bearing groups. Conclusions Leucine supplementation during pregnancy in tumor-bearing rats promoted high leucine absorption, increasing the availability of the amino acid for neoplasic cells and, mainly, for fetus and host utilization. This may have contributed to the better preservation of body weight gain, food intake and muscle protein observed in the supplemented rats in relation to the non-supplemented ones.

  20. Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats

    International Nuclear Information System (INIS)

    Ventrucci, Gislaine; Mello, Maria Alice Roston de; Gomes-Marcondes, Maria Cristina Cintra

    2002-01-01

    It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal muscle. To evaluate the effects of a leucine supplemented diet on the intestinal absorption alterations produced by Walker 256, growing pregnant rats were distributed into six groups. Three pregnant groups received a normal protein diet (18% protein): pregnant (N), tumor-bearing (WN), pair-fed rats (Np). Three other pregnant groups were fed a diet supplemented with 3% leucine (15% protein plus 3% leucine): leucine (L), tumor-bearing (WL) and pair-fed with leucine (Lp). Non pregnant rats (C), which received a normal protein diet, were used as a control group. After 20 days, the animals were submitted to intestinal perfusion to measure leucine, methionine and glucose absorption. Tumor-bearing pregnant rats showed impairment in food intake, body weight gain and muscle protein content, which were less accentuated in WL than in WN rats. These metabolic changes led to reduction in both fetal and tumor development. Leucine absorption slightly increased in WN group. In spite of having a significant decrease in leucine and methionine absorption compared to L, the WL group has shown a higher absorption rate of methionine than WN group, probably due to the ingestion of the leucine supplemented diet inducing this amino acid uptake. Glucose absorption was reduced in both tumor-bearing groups. Leucine supplementation during pregnancy in tumor-bearing rats promoted high leucine absorption, increasing the availability of the amino acid for neoplasic cells and, mainly, for fetus and host utilization. This may have contributed to the better preservation of body weight gain, food intake and muscle protein observed in the supplemented rats in relation to the non-supplemented ones

  1. Determinants of dietary supplement use--healthy individuals use dietary supplements.

    Science.gov (United States)

    Kofoed, Christina L F; Christensen, Jane; Dragsted, Lars O; Tjønneland, Anne; Roswall, Nina

    2015-06-28

    The prevalence of dietary supplement use varies largely among populations, and previous studies have indicated that it is high in the Danish population compared with other European countries. The diversity in supplement use across countries indicates that cultural and environmental factors could influence the use of dietary supplements. Only few studies investigating the use of dietary supplements have been conducted in the Danish population. The present cross-sectional study is based on 54,948 Danes, aged 50-64 years, who completed self-administrated questionnaires on diet, dietary supplements and lifestyle between 1993 and 1997. A health index including smoking, physical activity, alcohol and diet, and a metabolic risk index including waist circumference, urinary glucose and measured hypertension were constructed. Logistic regression was used to investigate these determinants in relation to the intake of dietary supplements. We found that 71 % of the participants were dietary supplement users; female sex, older age groups and higher educated participants were more likely to be users of any dietary supplements. One additional point in the health index was associated with 19, 16 and 9 % higher likelihood of being user of any, more common and less common supplements, respectively. In the metabolic risk index, one additional point was associated with 17 and 16 % lower likelihood of being user of any supplement and more common supplements, respectively. No significant association was found for less common supplement use. In conclusion, those with the healthiest lifestyle were more likely to use dietary supplements. Thus, lifestyle and dietary composition should be considered as confounders on supplement use and health outcomes.

  2. High-intensity-exercise-induced intestinal damage is protected by fermented milk supplemented with whey protein, probiotic and pomegranate (Punica granatum L.).

    Science.gov (United States)

    Chaves, Fernanda M; Baptista, Igor L; Simabuco, Fernando M; Quaresma, Paula G F; Pena, Fabiola L; Bezerra, Rosangela M N; Pauli, Jose R; da Cunha, Diogo T; Campos-Ferraz, Patricia L; Antunes, Adriane E C

    2018-04-01

    Here we evaluated the effect of fermented milk supplemented with whey protein (approximately 80 % protein), probiotic (Bifidobacterium animalis subsp. lactis BB12) and pomegranate juice (Punica granatum L.) on the physical performance, intestinal motility and villi structure, inflammatory markers and intestinal microbiota of rats under high-intensity acute exercise. In all, twenty-four Wistar rats were separated into groups: control (Ctrl), supplemented (Supp), exercised (Exe) and exercised and supplemented (Exe+Supp). Rats in the Supp groups received fermented milk during 6 weeks by oral administration. At the end of the supplementation period, the Exe groups were submitted to high-intensity acute exercise on a treadmill. We found that intense acute exercise caused changes in the intestinal villi interspace, changes in the proportion of Lactobacillus species and an increase in Clostridium species, as well as a decrease in intestinal motility. Supplementation increased intestinal motility, and maintained the intestinal villi interspace and the natural microbiota proportions of the exercised rats. Physical performance was not improved by fermented milk supplementation. We conclude that the fermented milk containing whey protein, B. animalis (BB12) and pomegranate juice can re-establish intestinal microbiota and protect the animals from the undesirable effects of intense acute exercise.

  3. Supplementation of diets for weaned piglets withL-Valine and L-Glutamine+ L-Glutamic acid

    Directory of Open Access Journals (Sweden)

    Naiara Diedrich Rodrigues

    2015-10-01

    Full Text Available The objective of this study was to evaluate the effects of supplementation of diets for weaned piglets with L-valine and L-glutamine + L-glutamic acid on performance, frequency of diarrhea, organ weight, digesta pH, intestinal morphology, and economic viability. Seventy-two piglets with a live weight of 7.53 ± 0.84 kg and 24 days of age were used. The animals were submitted to the following four treatments from 24 to 46 days of age: diet not supplemented with amino acids (control diet, CD; diet supplemented with glutamine + glutamic acid (GD; diet supplemented with glutamine + glutamic acid + valine (GVD, and diet supplemented with valine (VD. Two sequential phases (pre-initial I and pre-initial II with a duration of 12 and 11 days, respectively, were established. A completely randomized design, consisting of six repetitions and three pigs per experimental unit, was used. Nine days after weaning, at 32 days of age, a piglet per pen was slaughtered for the evaluation of organ weight, digesta pH and intestinal morphology. All animals received a single diet from days 47 to 65. No effects on performance were observed during the pre-initial phases I and II; however, when the whole study period was considered (24 to 65 days of age, piglets fed GVD consumed less feed and exhibited better feed conversion than animals of the VD group. With respect to morphometric parameters, GD provided a greater ileal crypt depth than CD and VD. There was an economic advantage of diets supplemented with L-valine and L-glutamine + L-glutamic acid, validating their use in diets for weaned piglets until 46 days of age.

  4. SPORT SUPPLEMENTATION

    OpenAIRE

    Alexandаr Marinkov

    2016-01-01

    Sport supplementation is essential for athletes performance and achievements. The well balanced and structured supplementation is a challenge for sport medicine because must be done a balance between potential benefits and potential risks (anti-doping rule violations and others). In this review are structured the most used categories sport supplementations. Nutritional supplements used in sport could be divided in some main categories like: amino acids, vitamins, proteins and antioxidants. Fo...

  5. Chemical Reaction Engineering Applications in Non-traditional Technologies. A Textbook Supplement.

    Science.gov (United States)

    Savage, Phillip E.; Blaine, Steven

    1991-01-01

    A set of educational materials that have been developed which deal with chemical engineering applications in emerging technologies is described. The organization and the content of the supplemental textbook materials and how they can be integrated into an undergraduate reaction engineering course are discussed. (KR)

  6. Safety Evaluation Report related to the operation of Palo Verde Nuclear Generating Station, Units 1, 2, and 3 (Docket Nos. STN 50-528, STN 50-529, and STN 50-530). Supplement No. 9

    International Nuclear Information System (INIS)

    1985-12-01

    Supplement No. 9 to the Safety Evaluation Report for the application filed by Arizona Public Service Company et al. for licenses to operate the Palo Verde Nuclear Generating Station, Units 1, 2 and 3 (Docket Nos. STN 50-528/529/530), located in Maricopa County, Arizona, has been prepared by the Office of Nuclear Reactor Regulation of the Nuclear Regulatory Commission. The purpose of this supplement is to update the Safety Evaluation Report by providing an evaluation of: (1) additional information submitted by the applicant since Supplement No. 8 was issued; and (2) matters that the staff had under review when Supplement No. 8 was issued, specifically those issues which required resolution prior to Unit 2 fuel loading and testing up to 5% of full power

  7. Instructions for safe transport of radioactive materials

    International Nuclear Information System (INIS)

    2005-01-01

    This entrance includes 5 chapters and tables and supplement. Chapter I contains the definitions and general provisions contained 5 materials. Chapter II contains radioactive materials packaging and permissible limits and it contains 8 materials. The provisions of Chapter III contains descriptions Missionaries. Chapter IV describes shipping instructions. As for the separation of V It contains Final provisions. The entrance contains number of tables speaks of the basic values of radioactive isotopes and radiation also limits activity and the requirements of industrial parcels and limits transactions to transport freight containers, as well as the International Classification of hazardous materials. This also includes entrance to the Supplement to some forms and Alohat

  8. Características da carcaça e da carne de novilhos mantidos em pastagem de capim-marandu submetidos a diferentes estratégias de suplementação Carcass and meat traits from crossbred steers submitted to different supplementation strategies

    Directory of Open Access Journals (Sweden)

    Roberta Carrilho Canesin

    2006-12-01

    Full Text Available Este trabalho foi realizado com o objetivo de avaliar as características quantitativas e qualitativas da carcaça e da carne de 24 novilhos submetidos a três estratégias de suplementação em pastagem: SD - suplementação diária; DA - suplementação em dias alternados; e FS - suplementação oferecida de segunda à sexta-feira e suspensa aos sábados e domingos. Foram utilizados 24 bovinos mestiços (Bos indicus x Bos taurus com peso inicial de 230 kg mantidos em pastagem de Brachiaria brizantha cv. Marandu no período das águas de 2003 e nos períodos de seca e das águas de 2004, quando atingiram o peso de abate. O delineamento experimental utilizado foi o inteiramente casualizado, com três tratamentos e oito repetições. As características quantitativas e qualitativas da carcaça e da carne não foram influenciadas pelas diferentes estratégias de suplementação, mesmo quando o suplemento foi fornecido apenas em dias alternados ou quando não foi fornecido nos finais de semana. Na média, os animais apresentaram peso de abate de 468,21 kg de PV, rendimento de carcaça quente de 50,26%, área de olho-de-lombo de 59,67 cm² e espessura de gordura de 3,3 mm. A carne foi classificada como macia, com suculência e palatabilidade levemente acima da média.The objective of this trial was to evaluate quantitative and qualitative traits of carcass and meat from grazing steers submitted to one of the following three supplementation strategies: daily supplementation (DS, alternate days supplementation (AS or Monday to Friday supplementation (MFS. Twenty-four crossbred steers (Bos indicus x Bos taurus averaging 230 kg of initial body were used in a completely randomized block design (three treatments and eight replicates/treatment. Animals were maintained in pasture of Brachiaria brizantha cv. Marandu from the rainy season of 2003 to the dry and rainy seasons of 2004, when they reached the expected slaughter weight. The quantitative and

  9. Nuclear fuel reprocessing and high level waste disposal: informational hearings. Volume V. Reprocessing. Part 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-03-08

    Testimony was presented by a four member panel on the commercial future of reprocessing. Testimony was given on the status of nuclear fuel reprocessing in the United States. The supplemental testimony and materials submitted for the record are included in this report. (LK)

  10. Study of damage of graphite/epoxy composites submitted to repeated quasi-static shear loadings

    International Nuclear Information System (INIS)

    Khadhraoui-Lattreche, Malika

    1984-01-01

    Quasi static loading tests on composite materials with organic matrix allow the behaviour of the materials under repeated loadings to be studied while avoiding viscoelastic effects. In this research thesis, the author reports the study of one-directional composite samples submitted to static pure shear loadings which represent the most severe stress state for this type of material. The material behaviour has been determined by application of loads greater than the yield strength, and of zero torque unloads. This allowed cumulative residual deformations to be monitored, and the increasing evolution of this parameter to be studied with respect to the number of applied cycles. The author deduces from these results a characteristic law for the material which introduces a decoupling between the stress and the cumulative residual deformation. Thus, a method of prediction of cumulative residual deformations is developed. Besides, a brief application to another material seems to confirm this type of law, and suggests that its generalisation should be studied [fr

  11. Safety evaluation report related to the operation of Sequoyah Nuclear Plant, Units 1 and 2, Docket Nos. 50-327 and 50-328, Tennessee Valley Authority. Supplement No. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-08-01

    The purpose of this supplement is to further update the Safety Evaluation Report by providing (1) our evaluation of additional information submitted by the licensee since the issuance of Supplement No. 1 to the Safety Evaluation Report, (2) our evaluation and status of the Non-TMI-2 outstanding issues identified in Part I of SER Supplement No. 1, (3) our evaluation of TMI-2 requirements which must be completed prior to the issuance of a full-power operating license, (4) our evaluation of dated requirements which the licensee must implement by the dates identified in NUREG-0694, TMI-Related Requirements for New Operating Licenses, and (5) our evaluation of additional information for those sections of the Safety Evaluation Report where further discussion or changes are in order.

  12. Safety evaluation report related to the operation of Sequoyah Nuclear Plant, Units 1 and 2, Docket Nos. 50-327 and 50-328, Tennessee Valley Authority. Supplement No. 2

    International Nuclear Information System (INIS)

    1980-08-01

    The purpose of this supplement is to further update the Safety Evaluation Report by providing (1) our evaluation of additional information submitted by the licensee since the issuance of Supplement No. 1 to the Safety Evaluation Report, (2) our evaluation and status of the Non-TMI-2 outstanding issues identified in Part I of SER Supplement No. 1, (3) our evaluation of TMI-2 requirements which must be completed prior to the issuance of a full-power operating license, (4) our evaluation of dated requirements which the licensee must implement by the dates identified in NUREG-0694, TMI-Related Requirements for New Operating Licenses, and (5) our evaluation of additional information for those sections of the Safety Evaluation Report where further discussion or changes are in order

  13. Complementarity in dietary supplements and foods: are supplement users vegetable eaters?

    Science.gov (United States)

    Kang, Hyoung-Goo; Joo, Hailey Hayeon; Choi, Kyong Duk; Lee, Dongmin; Moon, Junghoon

    2017-01-01

    Background : The consumption of fruits, vegetables, and dietary supplements correlate. Most previous studies have aimed to identify the determinants of supplement uses or the distinct features of supplement users; this literature lacks a discussion on dietary supplement consumption as a predictor of fruit and vegetable consumption. Objective : This study examines how dietary supplement consumption correlates with fruit and vegetable consumption by combining scanner data and surveys of Korean household grocery shopping. Methods : Propensity score matching (PSM) is used to identify the relationship between dietary supplement consumption and fruit and vegetable consumption in a household. A logit regression using supplement consumption as the dependent variable is used. Then, the supplement takers (the treatment group) are matched with non-takers (the control group) based on the propensity scores estimated in the logit regression. The fruit and vegetable consumption levels of the groups are then compared. Results : We found that dietary supplement use is associated with higher fruit and vegetable consumption. This supports the health consciousness hypothesis based on attention bias, availability heuristics, the focusing effect, and the consumption episode effect. It rejects the health substitute hypothesis based on economic substitutes and mental accounting. Conclusions : Future research on the health benefits of dietary supplements should address the complementary consumption of fruits/vegetables and their health benefits to avoid misstating the health effects of supplements.

  14. Young modulus variation of a brickwork masonry element submitted to high temperatures

    Directory of Open Access Journals (Sweden)

    Maciá, M. E.

    2013-03-01

    Full Text Available In order to understand the thermal behavior of the masonry elements submitted to high temperatures we need to know the variation of their thermal properties with regard to the temperature. Submitted to high temperatures clay brick masonry presents thermomechanical effects (as the variation of Young's modulus, the thermal expansion of the unit and the mortar, spalling, losses of resistance … as well as variation of the properties of the material as result of its degradation. In this article the variation of the module of elasticity of the unit and the mortar is described with regard to high temperatures according to the state of the knowledge. In this article is also exposed the results obtained from the experimental program carried out on elements of clay brick masonry submitted to high temperatures in order to observe the variation of Young's module related to temperature.

    La definición del comportamiento térmico de los elementos de fábrica sometidos a la acción del fuego requiere del conocimiento de la variación de sus propiedades termomecánicas con respecto a la temperatura. Ante las altas temperaturas la fábrica cerámica presenta efectos termomecánicos, como la variación del módulo de Young entre otros, así como la variación de las propiedades del material debidas a la degradación del mismo. En este artículo se describe la variación del módulo de elasticidad de la pieza y el mortero con respecto a altas temperaturas según el estado del conocimiento y se exponen los resultados obtenidos del programa experimental llevado a cabo sobre elementos de fábrica sometidos a altas temperaturas con el fin de observar la variación del módulo de Young con respecto a la temperatura.

  15. Opposite lipemic response of Wistar rats and C57BL/6 mice to dietary glucose or fructose supplementation

    Directory of Open Access Journals (Sweden)

    C.R. Barbosa

    2007-03-01

    Full Text Available The metabolic effects of carbohydrate supplementation in mice have not been extensively studied. In rats, glucose- and fructose-rich diets induce hypertriacylglycerolemia. In the present study, we compared the metabolic responses to two monosaccharide supplementations in two murine models. Adult male Wistar rats (N = 80 and C57BL/6 mice (N = 60, after 3 weeks on a standardized diet, were submitted to dietary supplementation by gavage with glucose (G or fructose (F solutions (500 g/L, 8 g/kg body weight for 21 days. Glycemia was significantly higher in rats after fructose treatment (F: 7.9 vs 9.3 mM and in mice (G: 6.5 vs 10 and F: 6.6 vs 8.9 mM after both carbohydrate treatments. Triacylglycerolemia increased significantly 1.5 times in rats after G or F supplementation. Total cholesterol did not change with G treatment in rats, but did decrease after F supplementation (1.5 vs 1.4 mM, P < 0.05. Both supplementations in rats induced insulin resistance, as suggested by the higher Homeostasis Model Assessment Index. In contrast, mice showed significant decreases in triacylglycerol (G: 1.8 vs 1.4 and F: 1.9 vs 1.4 mM, P < 0.01 and total cholesterol levels (G and F: 2.7 vs 2.5 mM, P < 0.05 after both monosaccharide supplementations. Wistar rats and C57BL/6 mice, although belonging to the same family (Muridae, presented opposite responses to glucose and fructose supplementation regarding serum triacylglycerol, free fatty acids, and insulin levels after monosaccharide treatment. Thus, while Wistar rats developed features of plurimetabolic syndrome, C57BL/6 mice presented changes in serum biochemical profile considered to be healthier for the cardiovascular system.

  16. 12 CFR 516.110 - Who may submit a written comment?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Who may submit a written comment? 516.110 Section 516.110 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Comment Procedures § 516.110 Who may submit a written comment? Any person may submit a...

  17. Watermelon juice: a promising feedstock supplement, diluent, and nitrogen supplement for ethanol biofuel production

    Directory of Open Access Journals (Sweden)

    Bruton Benny D

    2009-08-01

    Full Text Available Abstract Background Two economic factors make watermelon worthy of consideration as a feedstock for ethanol biofuel production. First, about 20% of each annual watermelon crop is left in the field because of surface blemishes or because they are misshapen; currently these are lost to growers as a source of revenue. Second, the neutraceutical value of lycopene and L-citrulline obtained from watermelon is at a threshold whereby watermelon could serve as starting material to extract and manufacture these products. Processing of watermelons to produce lycopene and L-citrulline, yields a waste stream of watermelon juice at the rate of over 500 L/t of watermelons. Since watermelon juice contains 7 to 10% (w/v directly fermentable sugars and 15 to 35 μmol/ml of free amino acids, its potential as feedstock, diluent, and nitrogen supplement was investigated in fermentations to produce bioethanol. Results Complete watermelon juice and that which did not contain the chromoplasts (lycopene, but did contain free amino acids, were readily fermentable as the sole feedstock or as diluent, feedstock supplement, and nitrogen supplement to granulated sugar or molasses. A minimum level of ~400 mg N/L (~15 μmol/ml amino nitrogen in watermelon juice was required to achieve maximal fermentation rates when it was employed as the sole nitrogen source for the fermentation. Fermentation at pH 5 produced the highest rate of fermentation for the yeast system that was employed. Utilizing watermelon juice as diluent, supplemental feedstock, and nitrogen source for fermentation of processed sugar or molasses allowed complete fermentation of up to 25% (w/v sugar concentration at pH 3 (0.41 to 0.46 g ethanol per g sugar or up to 35% (w/v sugar concentration at pH 5 with a conversion to 0.36 to 0.41 g ethanol per g sugar. Conclusion Although watermelon juice would have to be concentrated 2.5- to 3-fold to serve as the sole feedstock for ethanol biofuel production, the results

  18. 29 CFR 4010.13 - Confidentiality of information submitted.

    Science.gov (United States)

    2010-07-01

    ... REPORTING AND DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.13 Confidentiality of information submitted. In accordance with § 4901.21(a)(3) of this chapter and ERISA section... 29 Labor 9 2010-07-01 2010-07-01 false Confidentiality of information submitted. 4010.13 Section...

  19. 46 CFR 154.430 - Material test.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Material test. 154.430 Section 154.430 Shipping COAST... § 154.430 Material test. (a) The membrane and the membrane supporting insulation must be made of... test for the membrane and the membrane supporting insulation must be submitted to the Commandant (CG...

  20. Long-term impact of zinc supplementation in sows

    NARCIS (Netherlands)

    Riet, Van Miriam M.J.; Bos, Emilie Julie; Ampe, Bart; Bikker, Paul; Vanhauteghem, Donna; Bockstaele, Van Filip; Cornillie, Pieter; Broeck, Van Den Wim; Laing, Du Gijs; Maes, Dominiek; Tuyttens, Frank A.M.; Janssens, Geert P.J.; Millet, Sam

    2018-01-01

    Objectives: To evaluate the long-term impact of zinc (Zn) supplementation on performance and Zn status biomarkers in sows and on whether this possible impact depends on housing conditions. Materials and methods: Six groups of sows were allotted to group housing on two different floor types during

  1. Materials behaviour in PWRs core

    International Nuclear Information System (INIS)

    Barbu, A.; Massoud, J.P.

    2008-01-01

    Like in any industrial facility, the materials of PWR reactors are submitted to mechanical, thermal or chemical stresses during particularly long durations of operation: 40 years, and even 60 years. Materials closer to the nuclear fuel are submitted to intense bombardment of particles (mainly neutrons) coming from the nuclear reactions inside the core. In such conditions, the damages can be numerous and various: irradiation aging, thermal aging, friction wear, generalized corrosion, stress corrosion etc.. The understanding of the materials behaviour inside the cores of reactors in operation is a major concern for the nuclear industry and its long term forecast is a necessity. This article describes the main ways of materials degradation without and under irradiation, with the means used to foresee their behaviour using physics-based models. Content: 1 - structures, components and materials: structure materials, nuclear materials; 2 - main ways of degradation without irradiation: thermal aging, stress corrosion, wear; 3 - main ways of degradation under irradiation: microscopic damaging - point defects, dimensional alterations, evolution of mechanical characteristics under irradiation, irradiation-assisted stress corrosion cracking (IASCC), synergies; 4 - forecast of materials evolution under irradiation using physics-based models: primary damage - fast dynamics, primary damage annealing - slow kinetics microstructural evolution, impact of microstructural changes on the macroscopic behaviour, insight on modeling methods; 5 - materials change characterization techniques: microscopic techniques - direct defects observation, nuclear techniques using a particle beam, global measurements, mechanical characterizations; 6 - perspectives. (J.S.)

  2. Efficacy of Long-Term Oral Vitamin B12 Supplementation after Total Gastrectomy: Results from a Prospective Study

    Directory of Open Access Journals (Sweden)

    Joana Moleiro

    2017-11-01

    Full Text Available Background/Objectives: Vitamin B12 (VB12 deficiency is a common complication after total gastrectomy which may be associated with megaloblastic anemia and potentially irreversible neurologic symptoms. Intramuscular supplementation of VB12 has been considered the standard treatment, although it is associated with high costs and patient discomfort. Patients/Methods: We performed a prospective uncontrolled study (ACTRN12614000107628 in order to evaluate the clinical and laboratory efficacy of long-term oral VB12 supplementation in patients submitted to total gastrectomy. All patients received daily oral VB12 (1 mg/day and were evaluated every 3 months (clinical and laboratory evaluation: hemoglobin, VB12, total iron, ferritin, and folate. Results: A total of 26 patients were included with a mean age of 64 years (29-79. Patients were included with a mean period of 65 months (3-309 after total gastrectomy. At inclusion time, 17/26 patients were under intramuscular VB12, and 9 had not started supplementation yet. There were normal serum VB12 levels in 25/26 patients (mean VB12 serum levels: 657 pg/mL. The mean follow-up period was 20 (8.5-28 months. During follow-up, all patients had normal VB12 levels and there was no need for intramuscular supplementation. The patient with low VB12 levels had an increase to adequate levels, which remained stable. There were no differences with statistical significance among VB12 levels at 6 (867 pg/mL, 12 (1,008 pg/mL, 18 (1,018 pg/mL, and 24 (1,061 pg/mL months. Iron and folate supplementation was necessary in 21 and 7 patients, respectively. Conclusions: Oral VB12 supplementation is effective and safe in patients who underwent total gastrectomy and should be considered the preferential form of supplementation.

  3. Determinants of dietary supplement use - healthy individuals use dietary supplements

    DEFF Research Database (Denmark)

    Kofoed, Christina L F; Christensen, Jane; Dragsted, Lars Ove

    2015-01-01

    influence the use of dietary supplements. Only few studies investigating the use of dietary supplements have been conducted in the Danish population. The present cross-sectional study is based on 54 948 Danes, aged 50-64 years, who completed self-administrated questionnaires on diet, dietary supplements...... and lifestyle between 1993 and 1997. A health index including smoking, physical activity, alcohol and diet, and a metabolic risk index including waist circumference, urinary glucose and measured hypertension were constructed. Logistic regression was used to investigate these determinants in relation...... to the intake of dietary supplements. We found that 71 % of the participants were dietary supplement users; female sex, older age groups and higher educated participants were more likely to be users of any dietary supplements. One additional point in the health index was associated with 19, 16 and 9 % higher...

  4. The effect of caffeine supplementation on trained individuals ...

    African Journals Online (AJOL)

    Background: Intense physical training increases oxidative stress and inflammation, resulting into muscle and cellular damage. The aim of this study was to analyze the effect of caffeine supplementation on trained young individuals subjected to two treadmill maximal tests. Materials and Methods: It was a double-blind and ...

  5. Energy Materials Coordinating Committee (EMaCC). Annual technical report, fiscal year 1983

    International Nuclear Information System (INIS)

    1984-03-01

    The following text briefly describes the materials research programs of the Department of Energy. It is organized by office and organizational charts are provided to allow easy identification of the materials research programs of each office. These program descriptions have been prepared from inputs submitted by many different EMaCC members. This report is not a comprehensive summary of the Department's programs, but rather a compilation of the programs of those offices that submitted inputs

  6. 30 CFR 285.607 - How do I submit my SAP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my SAP? 285.607 Section 285.607... Assessment Plan and Information Requirements for Commercial Leases § 285.607 How do I submit my SAP? You must submit one paper copy and one electronic version of your SAP to MMS at the address listed in § 285.110(a). ...

  7. A Checklist for Submitting Your Risk Management Plan (RMP)

    Science.gov (United States)

    Important information about 2014 submissions and a checklist to consider in preparing and resubmitting a 5-year update, as required by 40 CFR part 68. Use the RMP*eSubmit software application, which replaced RMP*Submit.

  8. CADMIUM AND ZINC CONCENTRATIONS IN THE HAIR AFTER OF ADULTS MAGNESIUM SUPPLEMENTATION

    Directory of Open Access Journals (Sweden)

    Anna Sałacka

    2010-03-01

    Full Text Available Background: Cadmium is a biological zinc antagonist and may interfere with metabolic zinc-regulated or zincdependent processes. The aim of this study was to assess the relationship between cadmium and zinc concentrations in the hair of adults after oral supplementation with magnesium. Material and methods: The levels of elements in the hair were determined by the inverse voltammetry. The analysis was performed on the hair of 32 people from the study group and 10 from the control group. Supplementation was performed using Slow-Mag B6. Results: Cadmium concentration in the study group before supplementation ranged from indeterminable levels, to 1,92 µg per gram of dry matter. The range of cadmium concentration after supplementation was between the indeterminable level, and 0,45 µg per gram of dry matter. Based on the statistical analysis, we found that cadmium concentration was significantly lower after magnesium supplementation with a significance level of p*0,02. Zinc level before supplementation was between 11,66 and 250,48 µg per gram of dry matter, and after supplementation between 68,31 and 185,24 µg per gram of dry matter. Conclusion: The results obtained suggest that supplementation with magnesium contributed to the lowering of cadmium concentration in the hair of the people examined.

  9. 42 CFR 405.809 - Opportunity to submit evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Opportunity to submit evidence. 405.809 Section 405.809 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Appeals Under the Medicare Part B Program § 405.809 Opportunity to submit...

  10. Effect of Iron Containing Supplements on Rats' Dental Caries Progression

    Directory of Open Access Journals (Sweden)

    AR. Eshghi

    2012-01-01

    Full Text Available Objective: Iron deficiency is the most common form of malnutrition in developing countries. Iron containing supplements have been used effectively to solve this problem. In children, because of teeth staining after taking iron drops, parents have the idea that iron drops are the cause of tooth decay; therefore, they limit thisvital supplement in their children’s diet. Hereby, we evaluate the histologic effect of iron containing supplements on tooth caries in rice rats with cariogenic or noncariogenic diet.Materials and Methods: Twelve rats were selected and divided into four groups for this interventional experimental study. Four different types of dietary regimens were used for four months; group A, cariogenic diet with iron containing supplements; group B, cariogenic diet without iron containing supplements; groupC, non-cariogenic diet with iron containing supplements; group D, non-cariogenic diet without iron containing supplements. After sacrificing the rats, 20-micron histological sections of their posterior teeth were prepared using the Ground Sectionmethod, then they were studied under polarized light microscopy. In order to compare the progression of caries in different samples, the depth of the lesions in the enamel was measured as three grades I, II and III.Results: The mean grade value of A, B, C and D groups were 1.61, 2.61, 1.37 and 1.80, respectively. Statistical analysis revealed that significantly fewer caries were seen in the group which had received iron containing supplements and cariogenicdiet compared with cariogenic diet without iron supplements (p<0.05.Conclusion: Ferrous sulfate reduces the progression of dental caries in the cariogenic dietary regimen.

  11. Energy Materials Coordinating Committee (EMaCC). Annual technical report, fiscal year 1983

    Energy Technology Data Exchange (ETDEWEB)

    None

    1984-03-01

    The following text briefly describes the materials research programs of the Department of Energy. It is organized by office and organizational charts are provided to allow easy identification of the materials research programs of each office. These program descriptions have been prepared from inputs submitted by many different EMaCC members. This report is not a comprehensive summary of the Department's programs, but rather a compilation of the programs of those offices that submitted inputs.

  12. The impact of a diphenyl diselenide-supplemented diet and aerobic exercise on memory of middle-aged rats.

    Science.gov (United States)

    Cechella, José L; Leite, Marlon R; Gai, Rafaela M; Zeni, Gilson

    2014-08-01

    Selenium is an essential trace element for human health and has received attention for its role as a nutrient. The combination of exercise and nutrients has been proposed to promote health. The aim of this study was to determine the effects of a diet supplemented with diphenyl diselenide (PhSe)2 and swimming exercise on memory of middle-aged rats. Male Wistar rats (12months) received standard diet chow supplemented with 1ppm of (PhSe)2 for 4weeks. Rats were submitted to swimming training (20min per day for 4weeks). After 4weeks, memory was evaluated in the object recognition test (ORT) and in the object location test (OLT). The hippocampal levels of phosphorylated cAMP-response element-binding protein (CREB) were determined. The results of the present study demonstrated that the association of (PhSe)2-supplemented diet and swimming exercise improved short-term memory, long-term memory and spatial learning, and this effect was not related to the increase in hippocampal p-CREB levels in middle-age rats. This study also revealed that middle-aged rats in the swimming exercise group had the best performance in short- and long-term memory. In conclusion, we demonstrated that swimming exercise, (PhSe)2-supplemented diet or the association of these factors improved learning and memory functioning. The hippocampal levels of CREB were not directly related to the benefits of swimming exercise and (PhSe)2-supplemented diet association in memory of middle-aged rats. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Determination of campesterol, stigmasterol, and beta-sitosterol in saw palmetto raw materials and dietary supplements by gas chromatography: single-laboratory validation.

    Science.gov (United States)

    Sorenson, Wendy R; Sullivan, Darryl

    2006-01-01

    In conjunction with an AOAC Presidential Task Force on Dietary Supplements, a method was validated for measurement of 3 plant sterols (phytosterols) in saw palmetto raw materials, extracts, and dietary supplements. AOAC Official Method 994.10, "Cholesterol in Foods," was modified for purposes of this validation. Test samples were saponified at high temperature with ethanolic potassium hydroxide solution. The unsaponifiable fraction containing phytosterols (campesterol, stigmasterol, and beta-sitosterol) was extracted with toluene. Phytosterols were derivatized to trimethylsilyl ethers and then quantified by gas chromatography with a hydrogen flame ionization detector. The presence of the phytosterols was detected at concentrations greater than or equal to 1.00 mg/100 g based on 2-3 g of sample. The standard curve range for this assay was 0.00250 to 0.200 mg/mL. The calibration curves for all phytosterols had correlation coefficients greater than or equal to 0.995. Precision studies produced relative standard deviation values of 1.52 to 7.27% for campesterol, 1.62 to 6.48% for stigmasterol, and 1.39 to 10.5% for beta-sitosterol. Recoveries for samples fortified at 100% of the inherent values averaged 98.5 to 105% for campesterol, 95.0 to 108% for stigmasterol, and 85.0 to 103% for beta-sitosterol.

  14. Properties of selected superconductive materials, 1978 supplement. Technical note

    International Nuclear Information System (INIS)

    Roberts, B.W.

    1978-10-01

    This report includes data on additional superconductive materials extracted from the world literature up to fall 1977 and is an addendum to the data set published in J. Phys. Chem. Ref. Data 5, no. 3, 581-821 (1976) (Reprint no. 84). The data presented are new values and have not been selected or compared to values (except for selected values of the elements) previously assembled by the Superconductive Materials Data Center. The properties included are composition, critical temperature, critical magnetic field, crystal structure and the results of negative experiments. Special tabulations of high magnetic field materials with Type II behavior and materials with organic components are included. All entries are keyed to the literature. A list of recent reviews centered on superconductive materials is included

  15. Alternative sources of supplements in Africanized honeybees submitted to royal jelly production - doi: 10.4025/actascianimsci.v35i2.16976

    Directory of Open Access Journals (Sweden)

    Fabiana Martins Costa-Maia

    2013-03-01

    Full Text Available This study was carried out to evaluate the effect of supplements with isolated soy protein, brewer’s yeast, a mixture of isolated soy protein with brewer’s yeast, linseed oil, palm oil and mixture of linseed oil with palm oil in the royal jelly production of Africanized honey bee colonies. Total royal jelly produced was superior (P

  16. Material relating to the Chernobyl accident submitted by Belarus

    International Nuclear Information System (INIS)

    1996-01-01

    This material contains attachments provided by the Resident Representative of Belarus to the IAEA, who has requested that it be circulated to member states in connection with the First International Conference of the European Commission, Belarus, the Russian Federation and Ukraine on the consequences of the Chernobyl Accident held in Minsk held from 18 to 22 March 1996. The paper discusses the environmental and health effect of the accident and efforts made to assess and rehabilitate the environmental consequences. One of the obvious effect presented is a significant increase in incidence of thyroid cancer in children and adolescents

  17. Meat quality of suckling lambs supplemented with contents of crude glycerin in creep feeding

    Directory of Open Access Journals (Sweden)

    Ana Carolina Ribeiro Sanquetta de Pellegrin

    2014-10-01

    Full Text Available The objective of this research was to evaluate the effect of crude glycerin in the supplement provided in creep feeding on the physico-chemical and sensory characteristics of meat from suckling lambs kept in pasture ryegrass. Thirty two suckling lambs, sixteen male and sixteen female, were distributed into 4 diets with different concentrations of crude glycerin: 0, 10, 20 and 30% crude glycerin, in the replacement of corn, in the isoproteic supplement (18% CP provided daily in amounts equivalent to 2% of body weight. The experimental design was randomized blocks, with each variable data submitted to analysis of variance at 5% significance and the significant results subjected to regression analysis. There was no effect (P>0,05 of contents of crude glycerin on the chemical composition and cholesterol content of lamb meat. On the other hand, there was increased linearly (P>0,05 pH and cooking losses by the use of crude glycerin. No influence (P>0,05 of crude glycerin concentration on the texture profile analysis (TPA, sensorial analysis by triangular test and even when was evaluated attributes color, tenderness and juiciness of lamb meat. Up to 30% of crude glycerin in the supplement provided in creep feeding for suckling lambs grazing ryegrass do not compromise the physical-chemical and sensorial quality of the lamb meat.

  18. Bleaching agent action on color stability, surface roughness and microhardness of composites submitted to accelerated artificial aging.

    Science.gov (United States)

    Rattacaso, Raphael Mendes Bezerra; da Fonseca Roberti Garcia, Lucas; Aguilar, Fabiano Gamero; Consani, Simonides; de Carvalho Panzeri Pires-de-Souza, Fernanda

    2011-04-01

    The purpose of this study was to evaluate the bleaching agent action on color stability, surface roughness and microhardness of composites (Charisma, Filtek Supreme and Heliomolar - A2) submitted to accelerated artificial aging (AAA). A Teflon matrix (12 x 2 mm) was used to fabricate 18 specimens (n=6) which, after polishing (Sof-Lex), were submitted to initial color reading (ΔE), Knoop microhardness (KHN) (50 g/15 s load) and roughness (R(a)) (cut-off 0.25 mm) tests. Afterwards, the samples were submitted to AAA for 384 hours and new color, microhardness and roughness readings were performed. After this, the samples were submitted to daily application (4 weeks) of 16% Carbamide Peroxide (NiteWhite ACP) for 8 hours and kept in artificial saliva for 16 hours. New color, microhardness and roughness readings were made at the end of the cycle, and 15 days after bleaching. Comparison of the ΔE means (2-way ANOVA, Bonferroni, P<.05) indicated clinically unacceptable color alteration for all composites after AAA, but without significant difference. Statistically significant increase in the KHN values after AAA was observed, but without significant alterations 15 days after bleaching. For R(a) there was no statistically significant difference after AAA and 15 days after bleaching. The alterations promoted by the bleaching agent and AAA are material dependent.

  19. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 1: Investigation report

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Hau, J. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations.

  20. List of Nuclear Materials Licensing Actions Received

    Data.gov (United States)

    Nuclear Regulatory Commission — A catalog of all Materials Licensing Actions received for review. The catalog lists the name of the entity submitting the license application, their city and state,...

  1. Designing and Developing Supplemental Technology of PACI Model Materials through Blended Learning Methods

    Directory of Open Access Journals (Sweden)

    Effendi Limbong

    2017-06-01

    Full Text Available The 21st century English teachers and lecturers are required to have competencies in translating Content Knowledge (CK, integrating various Pedagogical Knolwedge (PK and implementing Technological Knowledge (TK in order to produce effective and efficient teaching. This research reveals and describes researchers efforts and pre-service EFL teachers (PSEFLTs roles in designing and developing the supplemental teaching and learning materials with PowerPoint, Audacity, Camtasia and Internet. To transform researcher roles and model to introduce and implement Technological, Pedagogical, and Content Knowledge (TPACK framework, this research implemented blended learning: traditional face to face (F2F and Facebook closed-group discussion (FBcgD based on Project-Based Learning (PBL. This research employed the qualitative autobiography narrative of self-study from the researchers experiences to implement blended learning. Semi-structure interviews were conducted with four PSEFLTs of group A and five PSEFLTs of group B to seek the PSEFLTs experiences in designing and developing PACI model. The results suggested that blended learning is can effectively and efficiently integrate and implement the design and development of a PACI model. Most importantly both of researcher and two groups realized that in integration of TPACK during a Computer Literacy course, the subject matter may be shaped by the application of technology; teaching as well as learning might be changed by the use of technology and the way to represent and communicate specific lessons to students.

  2. Complex Dietary Supplements from Raw Plants Provide Nutrition for Athletes

    Directory of Open Access Journals (Sweden)

    Dmitriy M. Uvarov

    2017-03-01

    Full Text Available The aim of this study was to investigate the effectiveness of mechanically activated complexes from plant substances to enhance athletes’ adaptability to intense physical activity. Methods: The object of the study was the dietary supplement Kladorod, which is based on the reindeer lichen Cladonia rangiferina and Rhodiola rosea in weight ratio of 10:1. To test the dietary supplement, we developed a special scheme for the experiment and selected 10 elite athletes (boxers and mixfighters. Athletes were divided into 2 groups and were under the same conditions (nutrition, medical monitoring, living conditions and training process. Athletes of the experimental group were given the dietary supplement Kladorod (capsule of 0.4 g by mouth between meals 4 times a day for 28 days. The control group was given placebo (Ringer-Locke powder capsules in the same terms in a similar way. During the experiment, the athletes were medically examined 3 times: at the beginning, in the middle, and after the course of intervention. We measured muscle performance, fat mass, muscle mass, and serum concentrations of cortisol and total testosterone. Results: It was established that during the intensive training of boxers and mixfighters for rating fights, administration of the dietary supplement Kladorod for 28 days stabilized the absolute and relative muscle mass, preventing its reduction, in comparison with the placebo group. At the same time, indicators of fat mass decreased significantly in the experimental group. After administering the course of Kladorod, we did not observe a significant decrease in testosterone/cortisol ratio, compared to the control group Thus, the use of biologically active supplements based on lichen raw materials and complexes of lichen raw materials with different plant substances enables the body to increase its adaptive potential and physical capacity.

  3. Coenzyme Q10 Supplementation Decreases Statin-Related Mild-to-Moderate Muscle Symptoms: A Randomized Clinical Study

    OpenAIRE

    Skarlovnik, Ajda; Janić, Miodrag; Lunder, Mojca; Turk, Martina; Šabovič, Mišo

    2014-01-01

    Background Statin use is frequently associated with muscle-related symptoms. Coenzyme Q10 supplementation has yielded conflicting results in decreasing statin myopathy. Herein, we tested whether coenzyme Q10 supplementation could decrease statin-associated muscular pain in a specific group of patients with mild-to-moderate muscle symptoms. Material/Methods Fifty patients treated with statins and reporting muscle pain were recruited. The Q10 group (n=25) received coenzyme Q10 supplementation o...

  4. Development of a supplemental surveillance program for reactor pressure vessel thermal annealing

    International Nuclear Information System (INIS)

    Server, W.L.; Rosinski, S.T.

    1997-01-01

    The technical decision to thermally anneal a nuclear reactor pressure vessel (RPV) depends upon the level of embrittlement in the RPV steels, the amount of recovery of fracture toughness properties expected from the anneal, and the rate of re-embrittlement after the vessel is placed back into service. The recovery of Charpy impact toughness properties after annealing can be estimated initially by using a recovery model developed using experimental measurements of recovery (such as that developed by Eason et al. for U.S. vessel materials). However, actual validation measurements on plant-specific archived vessel materials (hopefully in the existing surveillance program) are needed; otherwise, irradiated surrogate materials, essentially the same as the RPV steels or bounding in expected behavior, must be utilized. The efficient use of any of these materials requires a supplemental surveillance program focused at both recovery and reirradiation embrittlement. Reconstituted Charpy specimens and new surveillance capsules will most likely be needed as part of this supplemental surveillance program. A new version of ASTM E 509 has recently been approved which provides guidance on thermal annealing in general and specifically for the development of an annealing supplemental surveillance program. The post-anneal re-embrittlement properties are crucial for continued plant operation, and the use of a re-embrittlement model, such as the lateral shift approach, may be overly conservative. This paper illustrates the new ASTM E 509 Standard Guide methodology for an annealing supplemental surveillance program. As an example, the proposed program for the Palisades RPV beltline steels is presented which covers the time from annealing to the end of operating license and beyond, if license renewal is pursued. The Palisades nuclear power plant RPV was planned to be annealed in 1998, but that plant is currently being re-evaluated. The proposed anneal was planned to be conducted at a

  5. Pullout bond strength of fiber posts luted to different depths and submitted to artificial aging.

    Science.gov (United States)

    Macedo, V C; Souza, N A Y; Faria e Silva, A L; Cotes, C; da Silva, C; Martinelli, M; Kimpara, E T

    2013-01-01

    The extension of fiber post cementation often does not seem to influence the fracture resistance of restorations. This study evaluated the effects of cementation depths on the retention of fiber posts submitted to artificial aging. One hundred and sixty bovine incisors were selected to assess post retention. Following endodontic treatment, the canals were flared with diamonds burs. Postholes were prepared in lengths of 5 or 10 mm, after which fiber posts were relined with composite resin and luted with RelyX ARC or RelyX Unicem. The samples were then submitted to thermal and/or mechanical cycling before testing their pullout bond strengths. Absence of cycling was used as a control. The results of each cement were submitted to two-way and post hoc Tukey tests (α=0.05). Independent of the aging protocol, a depth of 10 mm showed higher pullout bond strength than did 5 mm, except for RelyX Unicem without cycling. For RelyX ARC, thermomechanical cycling resulted in lower values than in the absence of cycling. Mechanical cycling alone promoted the highest bond strength when the posts were luted with RelyX Unicem. The effect of artificial aging on the pullout bond strength is dependent on the type of material and the depth.

  6. Dietary supplement intake by recreationally trained men and motives behind these procedures

    Directory of Open Access Journals (Sweden)

    Anna Maria Kurylas

    2017-01-01

    Full Text Available Introduction: In the last 2-3 decades a significant increase in consumption of dietary supplements in physically active subjects has been observed. Supplements are easily accessible as they are sold by numerous companies on-line or at most food markets and pharmacies. Physically active men and women are constantly adding new supplements to their diets. Most scientists agree that exercise performance can be improved only through a combination of a proper training program, a well-balanced diet and specific supplementation geared to individual needs. Objective: The main objective of this research was to assess the type of supplements used by recreationally trained men in fitness clubs. Additionally the motives behind using particular supplements were evaluated. Material and methods: The research was conducted through interviews directly at fitness clubs and through the internet. The research subjects include 99 men between the age of 20 and 40 training at fitness clubs on a regular basis. The statistical analysis was conducted with the Statistica Microsoft Office Excel 2013 program. Results: From the 99 interviewed subjects 79% used supplements, with 47% declaring the objective of enhanced performance. Complex vitamin-mineral products were the most popular supplements among the interviewed group. The second most often used supplements included protein powders (52%, as well as protein-carbohydrate complexes and carbohydrate powders or liquids. According to the interviewed men creatine monohydrate was the most effective single supplement (25%. Conclusions: The most often reported motive for supplementation intake of recreationally trained men included enhanced performance and supplementation of daily diet. Taking into consideration the very dynamic development of dietary supplements industry such research should be conducted on a regular basis in different populations of men and women at a wide age scope.

  7. Staff supplement to the draft report on human engineering guide to control room evaluation: response to comments, sample checklist, draft systems review guidelines, and evaluation procedures

    International Nuclear Information System (INIS)

    1981-03-01

    This staff supplement to Draft Report NUREG/CR-1580, Human Engineering Guide to Control Room Evaluation, provides staff responses to comments on the draft report and supplemental material not provided in the draft report. The supplemental material includes new draft guidelines for the systems review of nuclear power plant control rooms and sample checklists and corresponding human engineering guidelines

  8. 30 CFR 218.580 - When do I submit Form MMS-4444?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When do I submit Form MMS-4444? 218.580 Section 218.580 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE... Correspondence § 218.580 When do I submit Form MMS-4444? Initially, you must submit MMS Form-4444 by November 29...

  9. 45 CFR 149.320 - Universe of claims that must be submitted.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

  10. Green tea supplementation produces better neuroprotective effects than red and black tea in Alzheimer-like rat model.

    Science.gov (United States)

    Schimidt, Helen L; Garcia, Alexandre; Martins, Alexandre; Mello-Carpes, Pamela B; Carpes, Felipe P

    2017-10-01

    Green tea from Camellia sinensis plays a neuroprotective role in different neurodegenerative conditions, such as memory deficits in Alzheimer disease (AD). However, whether other teas from Camellia sinensis present similar neuroprotective effect still is not clear. Here we investigate effects of green, red and black tea supplementation on memory and hippocampus oxidative status in a rat model of Alzheimer-like disease (AD-like). Wistar male rats were supplemented with green, red or black tea during 8weeks before Aβ intra-hippocampal injection (2μL of Aβ-25-35, CA1 region). AD and sham rats were submitted to memory tests. After euthanasia, oxidative status in the bilateral hippocampus was quantified. Green and red teas avoid memory deficits in AD rats, but only green tea also avoids oxidative stress and damage in the hippocampus. Green tea was more effective for neuroprotection than red and black teas from the Camellia sinensis in the AD rat model. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Effect of superoxide dismutase supplementation on sperm DNA fragmentation

    Directory of Open Access Journals (Sweden)

    Luciano Negri

    2017-10-01

    Full Text Available Background: antioxidants supplementation improves sperm quality, but few trials have analyzed the effects on sperm DNA fragmentation (SDF. This study compares the effectiveness of SOD-based antioxidant supplementation plus hydroxytyrosol and carnosol in reducing SDF with other antioxidants without SOD, hydroxytyrosol, and carnosol. Materials and methods: men with high SDF at baseline were selected in our clinical database. The patients taken into account had a 2-month control. SDF was measured by Sperm Chromatin Dispersion test (SCD. Untreated men were used as a control group. The remaining subjects received some oral antioxidant supplements (12 different combinations of both hydrophilic and lipophilic antioxidants, with some of them receiving nutritional support with a SOD-based antioxidant supplementation plus hydroxytyrosol and carnosol. Results: 118 men were selected for a retrospective study. Mean age 39.3 ± 5.4 years. Fifteen had no treatment, 55 were treated with a SOD-based antioxidant supplementation plus hydroxytyrosol and carnosol, and 48 took some antioxidant supplements for 2 months. Clinically, variations of at least 10% in baseline values of classic semen parameters and sperm DNA fragmentation were taken into consideration. Classic seminal parameters did not vary significantly in the three groups, with the exception of viability (p = 0.001. We assessed which of the active substances (no. 19 in different formulations were associated with variations in SDF. In the multivariable analysis of the 7 active substances that passed the univariable analysis, only the SOD molecule appeared to be linked to an improvement in SDF (< 0.0001. In detail, only one patient in the control group showed a spontaneous improvement in SDF (6%, compared to 16/48 (33% of those taking various oral antioxidant supplements, and 31/55 (56% of those taking a SOD-based antioxidant supplementation plus hydroxytyrosol and carnosol. Conclusions: SOD

  12. Fossil flora of Middle Jurassic Grojec clays (southern Poland. Raciborski’s original material reinvestigated and supplemented. I. Sphenophytes

    Directory of Open Access Journals (Sweden)

    Jarzynka Agata

    2015-12-01

    Full Text Available Sphenopsid remains from Grojec clays (Grojec, Poręba, Mirów collected and described by Raciborski in 1894 are re-examined for the first time and supplemented by Raciborski’s unpublished material housed at the Jagiellonian University (Institute of Botany and by Stur’s preliminarily described material stored at the Geological Survey of Austria. Three species of Equisetum created by Raciborski (Equisetum renaulti, E. remotum, E. blandum are now attributed to the common Jurassic species Equisetites lateralis, and the earlierundescribed Equisetites cf. columnaris is recognised. The occurrence of Neocalamites lehmannianus (originally described by Raciborski as Schizoneura hoerensis has been confirmed from Grojec. The material that Raciborski referred to this species seems to be heterogeneous, and some specimens are now removed to the new proposed species Neocalamites grojecensis Jarzynka et Pacyna sp. nov. The new species is diagnosed by the following features: only a few prominent ribs present on shoot, leaf scars relatively large and ellipsoidal, numerous free leaves, vascular bundles alternate at node. Possibly the new species derives from Neocalamites lehmannianus or at least is closely related to it. Part of the poorly preserved remains can be determined only as Neocalamites sp. Another species created by Raciborski, Phyllotheca (? leptoderma, is based on poorly preserved type specimens. Some of the unpublished specimens stored at the Jagiellonian University (Institute of Botany correspond to Raciborski’s description, but considering the poor preservation of the original material and the not very realistic published illustrations of this species, they rather should be regarded as indeterminate cortical fragments of Neocalamites lehmannianus and/or badly preserved external cortical surfaces of the new species Neocalamites grojecensis. Phyllotheca (? leptoderma should be considered a nomen dubium.

  13. Calcium supplements

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007477.htm Calcium supplements To use the sharing features on this page, please enable JavaScript. WHO SHOULD TAKE CALCIUM SUPPLEMENTS? Calcium is an important mineral for the ...

  14. Resveratrol food supplements

    DEFF Research Database (Denmark)

    Aschemann-Witzel, Jessica; Grunert, Klaus G

    2015-01-01

    Background: Consumers increasingly choose food supplements in addition to their diet. Research on supplement users finds they are likely to be female, older and well-educated; Furthermore, supplement users are often characterised as being especially health-oriented, an observation which is termed...... the ‘inverse supplement hypothesis’. However, results are dependent on the substance in question. Little is known so far about botanicals in general, and more specifically, little is known about resveratrol. The psychographic variables of food supplement users are yet relatively underexplored. By comparing US...... and Danish respondents, we aimed to identify whether sociodemographic variables, health status, health beliefs and behaviour and interest in food aspects specifically relevant to resveratrol (e.g., naturalness, indulgence, and Mediterranean food) explain favourable attitudes and adoption intentions toward...

  15. 33 CFR 160.210 - Methods for submitting an NOA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Methods for submitting an NOA... Conditions, and Certain Dangerous Cargos § 160.210 Methods for submitting an NOA. (a) Submission to the... the NVMC web site at http://www.nvmc.uscg.gov; (ii) Electronic submission of Extensible Markup...

  16. Health Food Supplements (Health Food Highly Nutritious From Chlorella And Oil Catfish (Pangasius hypopthalmus

    Directory of Open Access Journals (Sweden)

    Syahrul Syahrul

    2017-02-01

    Full Text Available AbstractThe utilization of microalgae as a food ingredient considered effective, because in addition to alternative food sources also contains nutrients chlorella microalgae in particular is very good for health. This microalgae rich in protein (60.5%, fat (11%, carbohydrates (20.1%, water, dietary fiber, vitamins and minerals Besides these microalgae contain pigments (chlorophyll, tocopherol and the active component (antimicrobial and antioxidants. This is what underlies microalgae is very useful to be used as a source of raw materials of health food supplements. Currently the health food supplements have become a necessity for people to maintain their health in order to remain vibrant. This study aims to produce high nutritious health food supplements from raw material chlorella enriched with fish protein concentrate and oil catfish. The method used in the manufacture of high nutritious health food supplement is a method of microencapsulation with different formulations. The results showed that the best formulations based on the profile of amino acids, fatty acids and standards AAE per day especially essential fatty acids oleic and linoleic is formulation B (chlorella 2%, 1% fish oil and fish protein concentrate 1%.

  17. 30 CFR 218.560 - How do I submit Form MMS-4444?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit Form MMS-4444? 218.560 Section... Correspondence § 218.560 How do I submit Form MMS-4444? A copy of Form MMS-4444 and instructions may be obtained from MMS. It will also be posted on the MMS Web site. Submit the completed, signed form to the address...

  18. 48 CFR 52.223-3 - Hazardous Material Identification and Material Safety Data.

    Science.gov (United States)

    2010-10-01

    ... offeror is the actual manufacturer of these items. Failure to submit the Material Safety Data Sheet prior... data. (f) Neither the requirements of this clause nor any act or failure to act by the Government shall... resistant envelope. [56 FR 55375, Oct. 25, 1991, as amended at 60 FR 34740, July 3, 1995; 62 FR 238, Jan. 2...

  19. Folic Acid Supplementation and Preterm Birth: Results from Observational Studies

    Directory of Open Access Journals (Sweden)

    Elena Mantovani

    2014-01-01

    Full Text Available Introduction. Folic acid (FA supplementation is recommended worldwide in the periconceptional period for the prevention of neural tube defects. Due to its involvement in a number of cellular processes, its role in other pregnancy outcomes such as miscarriage, recurrent miscarriage, low birth weight, preterm birth (PTB, preeclampsia, abruptio placentae, and stillbirth has been investigated. PTB is a leading cause of perinatal mortality and morbidity; therefore its association with FA supplementation is of major interest. The analysis of a small number of randomized clinical trials (RCTs has not found a beneficial role of FA in reducing the rate of PTBs. Aim of the Study. The aim of this review was to examine the results from recent observational studies about the effect of FA supplementation on PTB. Materials and Methods. We carried out a search on Medline and by manual search of the observational studies from 2009 onwards that analyzed the rate of PTB in patients who received supplementation with FA before and/or throughout pregnancy. Results. The results from recent observational studies suggest a slight reduction of PTBs that is not consistent with the results from RCTs. Further research is needed to better understand the role of FA supplementation before and during pregnancy in PTB.

  20. 30 CFR 210.101 - Who must submit production reports?

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.101 Who must submit production reports? (a... operator number. To obtain an operator number, refer to the MMS Minerals Production Reporter Handbook for... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who must submit production reports? 210.101...

  1. 76 FR 46790 - Combined Notice of Filings #1

    Science.gov (United States)

    2011-08-03

    .... Applicants: Orange Grove Energy, L.P. Description: J-Power North America Holdings Co. Ltd Supplemental Filing of Notification of Non-Material Change in Status Orange Grove Energy, L.P. Filed Date: 07/14/2011...: Upper Peninsula Power Company submits tariff filing per 35.12: Metering Agent Agreement between WPPI, L...

  2. Evaluation of congruence among dietary supplement use and motivation for supplementation in young, Canadian athletes.

    Science.gov (United States)

    Parnell, Jill A; Wiens, Kristin; Erdman, Kelly Anne

    2015-01-01

    Dietary supplement use is endemic in young athletes; however, it is unclear if their choices are congruent with their motivation for supplementation and the established benefits of the dietary supplements. The aim of this study was to evaluate the relationships between dietary supplement use and self-reported rationale in young athletes. Canadian athletes (n = 567; 11-25 years; 76% club or provincial level, 24% national or higher) completed a questionnaire designed to assess supplementation patterns and motivation for supplementation. Chi square tests examined associations between dietary supplements and self-reported rationale for use. Vitamin and mineral supplements, including vitamin-enriched water, were associated with several health- and performance- related reasons (p performance reasons, as were performance foods (protein powder, sport bars, sport gels, etc.). Plant extracts and fatty acids were primarily associated with health reasons, particularly immune support (p performance rationales and supplementation for common ergogenic aids, however, less so for vitamin and mineral supplements, vitamin-enriched water, and plant extracts. Incongruences were found between fatty acids, protein supplements, vitamin and mineral supplements, vitamin-enriched water, and plant extracts and health motivators for supplementation. Educational interventions are essential to ensure young athletes are using dietary supplements safely and effectively.

  3. Compliance of zinc supplementation by care givers of children suffering from diarrhea

    Directory of Open Access Journals (Sweden)

    Smita S Valekar

    2014-12-01

    Full Text Available Background: Over 2 million children die as a result of diarrhea and dehydration every year. A new ORS formula and introduction of Zinc supplementation offers much improved outcomes for the treatment of childhood diarrhea. Aims: To assess the compliance of Zinc supplementation by caregivers Objectives: 1. To assess the compliance of Zinc supplementation by caregivers, 2. To find out the reason for non-compliance 3. To study the association of socio-demographic variables and non-compliance of children suffering from diarrhea Materials & Method:  Study Design: Cross-sectional survey Study Period: from 1st Sept. 2014 to 31st Oct. 2014 Study Area: Pediatric Outpatient department of Tertiary Care Hospital Inclusion Criteria: Under five children suffering from diarrhea attending Pediatric OPD Study Tool: Questionnaire was administered to care givers and follow up was done on 3rd, 7th & 14th day of Zinc supplementation. Result: 84% of non-compliance was seen in this study. Conclusion: The compliance of Zinc supplementation is poor among caretakers of children suffering from diarrhea.

  4. Study of nutritional supplements using neutron activation analysis

    International Nuclear Information System (INIS)

    Reis, Rogerio Alves de Sousa; Saiki, Mitiko

    2005-01-01

    The increasing consumption of nutritional supplements among the people mainly aiming at the replacement of nutrients and minerals in the organism has led the commercialization of a great number of brands of these products. Consequently the quality control of these products is of great interest to verify if their element contents agree the values presented in labels or in the instructions for their uses. In this study the elements Ca, Co, Cr, Cu, Fe, K, Na, Se and Zn were analyzed in multimineral supplements and vitamins samples using neutron activation analysis method. The results obtained compared with the values of the labels of nutritional supplements presented good agreement. For quality control of the analytical data, certified reference materials NIST 1400 Bone Ash and NIST 1633b Coal Fly Ash provided by National Institute of Standards and Technology were analysed. Accuracy and precision of the results were evaluated and Z score values obtained were lower than 2 indicating that the data found are within the certified values at 95% of significance level. (author)

  5. Role of zinc supplementation in acute diarrhea in pre-school children

    International Nuclear Information System (INIS)

    Rao, M.Y.; Malik, B.; Raza, A.

    2017-01-01

    Objective: To monitor the therapeutic impact of zinc supplementation on clinical course of acute diarrhea i.e. frequency of stool, on stool amount and duration of acute diarrhea. Study Design: Randomized controlled trial. Place and Duration of Study: Family medicine department, PAF Hospital, Islamabad Pakistan from Jul to Dec 2009. Material and Methods: One hundred and twenty eight children aged 6 months to 60 months in an Outpatient pediatric department of PAF Hospital, E-9 Sector Islamabad with acute diarrhea of less than 14 days were included in this randomized controlled trial. They were further divided into two groups zinc supplemented group (n=65) and non-zinc supplemented group (n=65). Results: Baseline characteristics were similar in both the groups. Mean age in zinc supplemented group was 33.67 +- 16.45 months and in non-zinc supplemented group 33.63 +- 16.44 months. Reduction in stool frequency per day was found 62 percent in zinc supplemented group and 26 percent reduction was found in non-zinc supplemented group with obvious difference of 36 percent between these two groups from day 3 to day 5, which was found statistically significant (p=0.01). Similarly, significant difference (p=0.01) was observed for reduction in amount of stool per day from day 3 and day 5 with obvious difference of 45 percent between the study groups. Conclusions: Oral zinc administration in acute diarrhea reduces the frequency of diarrhea, output of stool and decreases total duration of diarrhea. (author)

  6. 40 CFR 60.2900 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

  7. Conjugated linoleic acid supplementation does not maximize motor performance and abdominal and trunk fat loss induced by aerobic training in overweight women

    Directory of Open Access Journals (Sweden)

    Fábio Luiz Cheche PINA

    Full Text Available ABSTRACT Objective: To analyze the effect of eight weeks of conjugated linoleic acid supplementation on physical performance, and trunk and abdominal fat in overweight women submitted to an aerobic training program. Methods: Twenty-eight overweight women (body mass index ³25 kg/m2 were divided randomly and double-blindly to receive conjugated linoleic acid or placebo, both associated with an aerobic exercise program (frequency = three times a week, duration=30 min/session, intensity=80% of maximum heart rate. Conjugated linoleic acid (3.2 g and placebo (4.0 g supplements were consumed daily (four capsules for eight weeks. Maximum speed and time to exhaustion were determined in incremental treadmill test. Trunk fat was estimated by dual-energy X-Ray absorptiometry. Waist circumference was used as indicator of abdominal fat. Results: Main effect of time (p0.05. Similarly, significant reductions (p0.05. Conclusion: The results of this study suggest that conjugated linoleic acid supplementation does not maximize motor performance, and loss of body and abdominal fat induced by aerobic training in overweight women.

  8. Creatine supplementation prevents acute strength loss induced by concurrent exercise.

    Science.gov (United States)

    de Salles Painelli, Vítor; Alves, Victor Tavares; Ugrinowitsch, Carlos; Benatti, Fabiana Braga; Artioli, Guilherme Giannini; Lancha, Antonio Herbert; Gualano, Bruno; Roschel, Hamilton

    2014-08-01

    To investigate the effect of creatine (CR) supplementation on the acute interference induced by aerobic exercise on subsequent maximum dynamic strength (1RM) and strength endurance (SE, total number of repetitions) performance. Thirty-two recreationally strength-trained men were submitted to a graded exercise test to determine maximal oxygen consumption (VO2max: 41.56 ± 5.24 ml kg(-1) min(-1)), anaerobic threshold velocity (ATv: 8.3 ± 1.18 km h(-1)), and baseline performance (control) on the 1RM and SE (4 × 80 % 1RM to failure) tests. After the control tests, participants were randomly assigned to either a CR (20 g day(-1) for 7 days followed by 5 g day(-1) throughout the study) or a placebo (PL-dextrose) group, and then completed 4 experimental sessions, consisting of a 5-km run on a treadmill either continuously (90 % ATv) or intermittently (1:1 min at vVO2max) followed by either a leg- or bench-press SE/1RM test. CR was able to maintain the leg-press SE performance after the intermittent aerobic exercise when compared with C (p > 0.05). On the other hand, the PL group showed a significant decrease in leg-press SE (p ≤ 0.05). CR supplementation significantly increased bench-press SE after both aerobic exercise modes, while the bench-press SE was not affected by either mode of aerobic exercise in the PL group. Although small increases in 1RM were observed after either continuous (bench press and leg press) or intermittent (bench press) aerobic exercise in the CR group, they were within the range of variability of the measurement. The PL group only maintained their 1RM. In conclusion, the acute interference effect on strength performance observed in concurrent exercise may be counteracted by CR supplementation.

  9. Effect of taking dietary supplement on hematological and biochemical parameters in male bodybuilders an equation model

    Science.gov (United States)

    Meamar, Rokhsareh; Maracy, Mohammad; Nematollahi, Shahrzad; Yeroshalmi, Shemouil; Zamani-Moghaddam, Ali; Ghazvini, Mohammad Reza Aghaye

    2015-01-01

    Background: The improved physical action following administration of supplements to bodybuilders was supported by changes in laboratory parameters. Despite the fact that these supplements are sometimes associated both advantage and side effects, this study were conducted for the purpose of evaluating the possible effects of some commonly used supplements in bodybuilders on the hematological and biochemical parameters. Materials and Methods: In this study, we included 40 male bodybuilders as cases and 40 controls in the age group of 20-40 years. They used different kinds of supplements for 1 year. In general, all the supplements used were classified into two groups: hormonal and non-hormonal. Laboratory tests were requested for evaluation of hematological and biochemical parameters. Results: In an equation model, we found that weight (P = 0.024), duration of bodybuilding (P bodybuilders. The available supplements are unchecked and not approved by the US Food and Drug Administration (FDA). More studies should be designed for a better and precise administration of each supplement in athletes. PMID:26793253

  10. 40 CFR 62.14715 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

  11. Botanical supplements: detecting the transition from ingredients to supplements

    Science.gov (United States)

    Methods were developed using flow injection mass spectrometry (FIMS) and chemometrics for the comparison of spectral similarities and differences of 3 botanical ingredients and their supplements: Echinacea purpurea aerial samples and solid and liquid supplements, E. purpurea root samples and solid s...

  12. Supplementation with humic substances affects the innate immunity in layer hens in posfasting phase

    Directory of Open Access Journals (Sweden)

    Rosa Sanmiguel P.

    2015-12-01

    Full Text Available Objective. Asses the effect of supplementation with Humic substances (HS over some innate immunity parameters (serum bactericidal activity, phagocytosis, bacterial agglutination, respiratory burst and lisozyme activity in phase after fasting of layer hens. Materials and methods. 120 posfasting phase Hy Line Brown layer hens were taken which were distributed into four groups: The first and the second were supplemented with 0.1 and 0.2% of HS, respectively. The third group was supplemented with 0.25 mg/kg on levamisole hydrochloride and fourth group have no supplementation; during sixty days period. Blood samples were collected on 8th, 30th and 60th of experiment day. Results. The phagocytic index and respiratory burst increased significantly at day 30th in HS supplemented groups. Alike, serum bactericidal activity and lisozyme activity improved on 8 th day, nevertheless, changes were no evident latter. The bacterial agglutination was high in supplemented groups evaluated at everyone times. Conclusions. Results showed that HS behave as immunostimulant in the early phase after fasting layer hens.

  13. 40 CFR 60.2060 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November...

  14. Removing Supplementary Materials from Montessori Classrooms Changed Child Outcomes

    Science.gov (United States)

    Lillard, Angeline S.; Heise, Megan J.

    2016-01-01

    Montessori classrooms vary in the degree to which they adhere to Maria Montessori's model, including in the provision of materials. Specifically, some classrooms use only Montessori materials, whereas others supplement the Montessori materials with commercially available materials like puzzles and games. A prior study suggested such…

  15. Vitamin A Oral Supplementation Induces Oxidative Stress and Suppresses IL-10 and HSP70 in Skeletal Muscle of Trained Rats

    Directory of Open Access Journals (Sweden)

    Lyvia Lintzmaier Petiz

    2017-04-01

    Full Text Available Exercise training intensity is the major variant that influences the relationship between exercise, redox balance, and immune response. Supplement intake is a common practice for oxidative stress prevention; the effects of vitamin A (VA on exercise training are not yet described, even though this molecule exhibits antioxidant properties. We investigated the role of VA supplementation on redox and immune responses of adult Wistar rats subjected to swimming training. Animals were divided into four groups: sedentary, sedentary + VA, exercise training, and exercise training + VA. Over eight weeks, animals were submitted to intense swimming 5 times/week and a VA daily intake of 450 retinol equivalents/day. VA impaired the total serum antioxidant capacity acquired by exercise, with no change in interleukin-1β and tumor necrosis factor-α levels. In skeletal muscle, VA caused lipid peroxidation and protein damage without differences in antioxidant enzyme activities; however, Western blot analysis showed that expression of superoxide dismutase-1 was downregulated, and upregulation of superoxide dismutase-2 induced by exercise was blunted by VA. Furthermore, VA supplementation decreased anti-inflammatory interleukin-10 and heat shock protein 70 expression, important factors for positive exercise adaptations and tissue damage prevention. Our data showed that VA supplementation did not confer any antioxidative and/or protective effects, attenuating exercise-acquired benefits in the skeletal muscle.

  16. 45 CFR 2523.110 - Can Federal agencies submit multiple applications?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Can Federal agencies submit multiple applications? 2523.110 Section 2523.110 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION... AMERICORPS PROGRAM ASSISTANCE § 2523.110 Can Federal agencies submit multiple applications? No. The...

  17. 40 CFR 60.3011 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

  18. 40 CFR 62.14585 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

  19. Quercetin supplemented diet improves follicular development, oocyte quality, and reduces ovarian apoptosis in rabbits during summer heat stress.

    Science.gov (United States)

    Naseer, Zahid; Ahmad, Ejaz; Epikmen, Erkmen Tuğrul; Uçan, Uğur; Boyacioğlu, Murat; İpek, Emrah; Akosy, Melih

    2017-07-01

    The present study was designed to test the modulatory effect of dietary quercetin on follicle population, apoptosis, in vitro maturation rate and quality of oocytes in heat stressed female rabbits. A total of thirty-four New Zealand White heat stress (HS) exposed female rabbits were either fed with quercetin supplemented diet (QU-HS) or non-supplemented (HS) diet. Firstly, laparotomy was performed for oocyte retrieval and then, oocyte grading and COCs dimensional assessments were conducted. The A and B-grade oocytes were submitted for in vitro maturation. Thereafter, the ovaries were collected from rabbits and were processed for follicular population estimation and granulosa cells apoptosis. The results showed that follicle number, retrieved oocytes and A-grade oocytes were higher in QU-HS, comparatively. A significant difference was observed in A-grade oocytes dimensions between QU-HS and HS treatment groups. The oocyte maturation rate was same across the groups. The quercetin supplementation significantly improved primordial and antral stage follicles. A greater number of apoptotic cells were observed in primary and antral follicles in the HS group. In conclusion, the quercetin provision improves the follicular development, minimize granulosa cells apoptosis, and maintain the oocyte competence in HS rabbits. Copyright © 2017. Published by Elsevier Inc.

  20. 40 CFR 60.2625 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2625 When must I submit my waste management plan? You must submit a waste management plan no later than the date specified in table 1 of this...

  1. 21 CFR 803.13 - Do I need to submit reports in English?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Do I need to submit reports in English? 803.13... in English? (a) Yes. You must submit all written or electronic equivalent reports required by this part in English. (b) If you submit any reports required by this part in an electronic medium, that...

  2. Final safety evaluation report related to the certification of the System 80+ design: Docket Number 52-002. Supplement 1

    International Nuclear Information System (INIS)

    1997-05-01

    This report supplements the final safety evaluation report (FSER) for the System 80+ standard design. The FSER was issued by the US Nuclear Regulatory Commission (NRC) staff as NUREG-1462 in August 1994 to document the NRC staff's review of the System 80+ design. The System 80+ design was submitted by Asea Brown Boveri-Combustion Engineering (ABB-CE), in accordance with the procedures of Subpart B to Part 52 of Title 10 of the Code of Federal Regulations. This supplement documents the NRC staff's review of the changes to the System 80+ design documentation since the issuance of the FSER. ABB-CE made these changes as a result of its review of the System 80+ design details. The NRC staff concludes that the changes to the System 80+ design documentation are acceptable, and that ABB-CE's application for design certification meets the requirements of Subpart B to 10 CFR Part 52 that are applicable and technically relevant to the System 80+ design

  3. Use of hormones and nutritional supplements among gyms' attendees in Riyadh

    Science.gov (United States)

    Alshammari, Sulaiman A.; AlShowair, Mishal A.; AlRuhaim, Abdulmalik

    2017-01-01

    BACKGROUND: Worldwide, studies have shown a high prevalence of hormones and nutritional supplement use by athletes and gym members. Many athletes consume unproven, potentially harmful or even banned supplements. OBJECTIVES: To assess the prevalence of the use of hormones and nutritional supplements by people who exercise in gyms in Riyadh, Saudi Arabia, and the types of supplements they most commonly use and to obtain a general view of the main reasons for using these enhancements. MATERIALS AND METHODS: A cross-sectional study using a self-administered questionnaire was conducted at gyms in Riyadh that were selected randomly from different sectors of the city. The sample size was estimated at 289, but the actual number of randomly selected participants in the study was 457. RESULTS: The number of gym members who participated in this study was 457. Approximately 47.9% of the sample reported an intake of nutritional supplements and 7.9% reported that they took hormones. Protein powder was consumed by 83.1% of the participants. Approximately 16.8% of supplement users had noticed some side effects, and 25.7% of those who took hormones had stopped taking them because of adverse effects. Only half of the hormone users (54.2%) reported that they had had medical checkups. The major source of information on supplement and hormone use was non-health professionals; friends being major source (40%) of information on the use of hormones. The use of nutritional supplements was significantly associated with BMI (OR = 1.89, CI = 1.06–3.39), duration of daily exercise (OR = 4.23, CI = 2.06–8.68), and following a special diet (OR = 8.42, CI = 5.37–13.2). There was a very strong association between nutritional supplement consumption and hormone use (P gyms took nutritional supplements, and most had received their information from nonhealth professionals. There was an association between the duration of exercise and the use of hormones and supplements. Fewer than half of

  4. Preparation of food supplements from oilseed cakes.

    Science.gov (United States)

    Sunil, L; Appaiah, Prakruthi; Prasanth Kumar, P K; Gopala Krishna, A G

    2015-05-01

    Oilseed cakes have been in use for feed preparation. Being rich in proteins, antioxidants, fibers, vitamins and minerals, oilseed cakes have been considered ideal for food supplementation. These oilseed cakes can be processed and made more palatable and edible by suitable treatments and then incorporated as food supplements for human consumption. Rice bran pellets (RBP), stabilized rice bran (SRB), coconut cake (CC) and sesame cake (SC) were taken up for the study. These were mixed with distilled water and cooked in such a way to separate the cooked solid residue and liquid extract followed by freeze drying to get two products from each. The raw, cooked dried residue and extract were analyzed for various parameters such as moisture (0.9-27.4 %), fat (2.1-16.1 %), ash (3.3-9.0 %), minerals (2.6-633.2 mg/100 g), total dietary fiber (23.2-58.2 %), crude fiber (2.7-10.5 %), protein (3.2-34.0 %), and the fat further analyzed for fatty acid composition, oryzanol (138-258 mg/100 g) and lignan (99-113 mg/100 g) contents and also evaluated sensory evaluation. Nutritional composition of products as affected by cooking was studied. The cooked products (residue and extract) showed changes in nutrients content and composition from that of the starting cakes and raw materials, but retained more nutrients in cooked residue than in the extract. The sensory evaluation of cooked residue and extract showed overall higher acceptability by the panelists than the starting cakes and raw materials. On the basis of these findings it can be concluded that these cooked residue and extract products are highly valuable for food supplementation than the raw ones.

  5. 40 CFR 167.90 - Where to obtain and submit forms.

    Science.gov (United States)

    2010-07-01

    ... establishments not found at the same location as their company headquarters, must submit applications and reports... establishments not found at the same location as their company headquarters to be submitted by the company headquarters to the Regional Office having jurisdiction over the State in which the company headquarters is...

  6. 30 CFR 253.40 - What OSFR evidence must I submit to MMS?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What OSFR evidence must I submit to MMS? 253.40... § 253.40 What OSFR evidence must I submit to MMS? (a) You must submit to MMS: (1) A single demonstration... unaltered Form MMS-1016; (3) MMS forms that identify your COFs (Form MMS-1021, Form MMS-1022), and the...

  7. 39 CFR 912.7 - Evidence and information to be submitted.

    Science.gov (United States)

    2010-07-01

    ... bearing on either the responsibility of the United States for the death or the damages claimed. (b... and information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other...

  8. 31 CFR 375.12 - How do I submit an offer?

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false How do I submit an offer? 375.12 Section 375.12 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... way for any unauthorized tender submissions or for any delays, errors, or omissions in submitting...

  9. Speciation of selenium dietary supplements; formation of S-(methylseleno)cysteine and other selenium compounds

    International Nuclear Information System (INIS)

    Amoako, Prince O.; Uden, Peter C.; Tyson, Julian F.

    2009-01-01

    Speciation of selenium is of interest because it is both essential and toxic to humans, depending on the species and the amount ingested. Following indications that selenium supplementation could reduce the incidence of some cancers, selenium-enriched yeast and other materials have been commercialized as supplements. Most dramatically however, the SELECT trial that utilized L-selenomethionine as the active supplement was terminated in 2008 and there is much debate regarding both the planning and the results of efficacy studies. Further, since dietary supplements are not regulated as pharmaceuticals, there are concerns about the quality, storage conditions, stability and selenium content in selenium supplements. Enzymatic hydrolysis enabled selenium speciation profiles to be obtained by high performance liquid chromatography with inductively coupled plasma mass spectrometry (HPLC-ICP-MS) and following derivatization gas chromatography with atomic emission detection (GC-AED). Coated fiber solid phase microextraction (SPME) was used to extract volatile selenium species for determination by GC-AED and GC-MS. Similar speciation patterns were observed between yeast-based supplements subject to extended storage and those heated briefly at elevated temperatures. All the yeast-based supplements and one yeast-free supplement formed S-(methylseleno)cysteine on heating. Evidence was obtained in support of the hypotheses that S-(methylseleno)cysteine is formed from a reaction between dimethyldiselenide and cysteine or cystine.

  10. 10 CFR 14.23 - Evidence and information to be submitted.

    Science.gov (United States)

    2010-01-01

    ... and death. (8) Any other evidence or information which may have a bearing on either the responsibility... Procedures and Requirements § 14.23 Evidence and information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1...

  11. 76 FR 26223 - Petition for Rulemaking Submitted by Thomas Popik

    Science.gov (United States)

    2011-05-06

    ... Rulemaking Submitted by Thomas Popik AGENCY: Nuclear Regulatory Commission. ACTION: Petition for rulemaking... filed with the NRC by Thomas Popik. The petition was docketed by the NRC on March 15, 2011, and has been... received a petition for rulemaking on March 14, 2011 (PRM- 50-96). The petition was submitted by Mr. Thomas...

  12. Hospital materials managers need to be aware of actions that constitute legal acceptance.

    Science.gov (United States)

    Decker, R

    1990-12-01

    A hospital invited bids for building materials for a hospital construction project. A supplier submitted a bid which asked the hospital to sign and return a trade association form contract. The hospital didn't return the form but used the supplier's bid as part of the general contract for the entire project and notified the supplier and the general contractor. Later, the supplier submitted a higher bid for the same material contending that the hospital hadn't accepted the first bid as they hadn't followed the instructions. The hospital materials manager feels that the bid was properly accepted. In this dialogue, Dr. Decker reviews the legal issues involved in the different ways of accepting an offer.

  13. Validation of an educative manual for patients with head and neck cancer submitted to radiation therapy 1

    Science.gov (United States)

    da Cruz, Flávia Oliveira de Almeida Marques; Ferreira, Elaine Barros; Vasques, Christiane Inocêncio; da Mata, Luciana Regina Ferreira; dos Reis, Paula Elaine Diniz

    2016-01-01

    Abstract Objective: develop the content and face validation of an educative manual for patients with head and neck cancer submitted to radiation therapy. Method: descriptive methodological research. The Theory of Psychometrics was used for the validation process, developed by 15 experts in the theme area of the educative manual and by two language and publicity professionals. A minimum agreement level of 80% was considered to guarantee the validity of the material. Results: the items addressed in the assessment tool of the educative manual were divided in three blocks: objectives, structure and format, and relevance. Only one item, related to the sociocultural level of the target public, obtained an agreement rate manual proposed were attended to. This can contribute to the understanding of the therapeutic process the head and neck cancer patient is submitted to during the radiation therapy, besides supporting clinical practice through the nursing consultation. PMID:27305178

  14. Active components in food supplements

    NARCIS (Netherlands)

    Siemelink M; Jansen EHJM; Piersma AH; Opperhuizen A; LEO

    2000-01-01

    The growing food supplement market, where supplements are both more diverse and more easily available (e.g. through Internet) formed the backdrop to the inventory of the active components in food supplements. The safety of an increased intake of food components via supplements was also at issue

  15. Determination of campesterol, stigmasterol, and beta-sitosterol in saw palmetto raw materials and dietary supplements by gas chromatography: collaborative study.

    Science.gov (United States)

    Sorenson, Wendy R; Sullivan, Darryl

    2007-01-01

    An interlaboratory study was conducted to evaluate a method for the determination of campesterol, stigmasterol, and beta-sitosterol in saw palmetto raw materials and dietary supplements at levels >1.00 mg/100 g based on a 2-3 g sample. Test samples were saponified at high temperature with ethanolic KOH solution. The unsaponifiable fraction containing phytosterols (campesterol, stigmasterol, and beta-sitosterol) was extracted with toluene. Phytosterols were derivatized to trimethylsilyl ethers and then quantified by gas chromatography with hydrogen flame ionization detection. Twelve blind duplicates, one of which was fortified, were successfully analyzed by 10 collaborators. Recoveries were obtained for the sample that was fortified. The results were 99.8, 111, and 111% for campesterol, stigmasterol, and beta-sitosterol, respectively. For repeatability, the relative standard deviation (RSDr) ranged from 3.93 to 17.3% for campesterol, 3.56 to 22.7% for stigmasterol, and 3.70 to 43.9% for beta-sitosterol. For reproducibility, the RSDR ranged from 7.97 to 22.6%, 0 to 26.7%, and 5.27 to 43.9% for campesterol, stigmasterol, and beta-sitosterol, respectively. Overall, the Study Director approved 5 materials with acceptable HorRat values for campesterol, stigmasterol, and beta-sitosterol ranging from 1.02 to 2.16.

  16. MICROBIOLOGICAL QUALITY OF FOOD SUPPLEMENTS.

    Science.gov (United States)

    Ratajczak, Magdalena; Kubicka, Marcelina M; Kamińska, Dorota; Długaszewska, Jolanta

    2015-01-01

    Many specialists note that the food offered today - as a result of very complex technological processing - is devoid of many components that are important for the organism and the shortages have to be supplemented. The simplest for it is to consume diet supplements that provide the missing element in a concentrated form. In accordance with the applicable law, medicinal products include all substances or mixtures of substances that are attributed with properties of preventing or treating diseases with humans or animals. Permits to admit supplements to the market are issued by the Chief Sanitary Inspector and the related authorities; permits for medicines are issued by the Chief Pharmaceutical Inspector and the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products. Therefore, admittance of a supplement to the market is less costly and time consuming_than admittance of a medicine. Supplements and medicines may contain the same component but medicines will have a larger concentration than supplements. Sale of supplements at drug stores and in the form of tablets, capsules, liquids or powders makes consumer often confusing supplements with medicines. Now there are no normative documents specifying limits of microbiological impurities in diet supplements. In Polish legislation, diet supplements are subject to legal acts concerning food. Medicines have to comply with microbiological purity requirements specified in the Polish Pharmacopeia. As evidenced with the completed tests, the proportion of diet supplement samples with microbiological impurities is 6.5%. Sales of diet supplements have been growing each year, they are consumed by healthy people but also people with immunology deficiencies and by children and therefore consumers must be certain that they buy safe products.

  17. 44 CFR 65.4 - Right to submit new technical data.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Right to submit new technical... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.4 Right to submit new technical data. (a) A community has..., other than those initiatedby FEMA, must be made in writing by the Chief Executive Officer of the...

  18. 37 CFR 2.54 - Requirements for drawings submitted on paper.

    Science.gov (United States)

    2010-07-01

    ... submitted on paper. 2.54 Section 2.54 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK... drawings submitted on paper. The drawing must meet the requirements of § 2.52. In addition, in a paper submission, the drawing should: (a) Be on non-shiny white paper that is separate from the application; (b) Be...

  19. 15 CFR 325.14 - Submitting reports.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Submitting reports. 325.14 Section 325.14 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE MISCELLANEOUS REGULATIONS EXPORT TRADE CERTIFICATES...

  20. Taking iron supplements

    Science.gov (United States)

    ... medlineplus.gov/ency/article/007478.htm Taking iron supplements To use the sharing features on this page, ... levels. You may also need to take iron supplements as well to rebuild iron stores in your ...

  1. Effects of zinc supplementation on sexual behavior of male rats

    Directory of Open Access Journals (Sweden)

    DMAB Dissanayake

    2009-01-01

    Full Text Available Context: Effects of zinc on male sexual competence are poorly understood. Aim: To study the effects of different doses of zinc on the sexual competence of males using a rat model. Materials and Methods: Three subsets (eight in each subset of sexually experienced adult male rats were supplemented with three different oral doses of zinc sulphate (a daily dose of 1 mg, 5 mg and 10 mg respectively for two weeks. A subset of eight animals without zinc supplementation was used as the control group Sexual behavior was observed by placing them individually in cages with receptive females. Statistical Analysis : Data analysis was done using SPSS v10 for windows computer software. Results: Supplementation of 5 mg of zinc/day for two weeks led to a prolongation of ejaculatory latency; 711.6 sec. (SEM 85.47 vs. 489.50 sec. (SEM 67.66, P 0.05. However, partner preference index was positive and 5 mg zinc supplementation did not exert a significant adverse effect on the muscle strength and co-ordination. The subset of rats supplemented with 1 mg/day did not show a difference from the control group while supplementation with 10 mg/day led to a reduction of the libido index, number of mounts and intromissions. Conclusions : Zinc therapy improves sexual competence of male rats; the effect is dose dependent. Increase in the T levels is beneficial in this regard. However, increase in PRL is responsible for the reduced libido index. Further studies on pigs and monkeys are needed to evaluate the therapeutic use of zinc in sexual dysfunction.

  2. 28 CFR 54.225 - Educational institutions eligible to submit transition plans.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Educational institutions eligible to submit transition plans. 54.225 Section 54.225 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED... Coverage § 54.225 Educational institutions eligible to submit transition plans. (a) Application. This...

  3. Fracture resistance of teeth submitted to several internal bleaching protocols.

    Science.gov (United States)

    Leonardo, Renato de Toledo; Kuga, Milton Carlos; Guiotti, Flávia Angélica; Andolfatto, Carolina; Faria-Júnior, Norberto Batista de; Campos, Edson Alves de; Keine, Kátia Cristina; Dantas, Andrea Abi Rached

    2014-03-01

    The aim of this study was to evaluate the fracture resistance of teeth submitted to several internal bleaching protocols using 35% hydrogen peroxide (35HP), 37% carbamide peroxide (37CP), 15% hydrogen peroxide with titanium dioxide nanoparticles (15HPTiO2) photoactivated by LED-laser or sodium perborate (SP). After endodontic treatment, fifty bovine extracted teeth were divided into five groups (n = 10): G1-unbleached; G2-35HP; G3-37CP; G4-15HPTiO2 photoactivated by LED-laser and G5-SP. In the G2 and G4, the bleaching protocol was applied in 4 sessions, with 7 days intervals between each session. In the G3 and G5, the materials were kept in the pulp teeth for 21 days, but replaced every 7 days. After 21 days, the teeth were subjected to compressive load at a cross head speed of 0.5 mm/min, applied at 135° to the long axis of the root using an eletromechanical testing machine, until teeth fracture. The data were submitted to ANOVA and Tukey tests (α = 5%). The 35HP, 37CP, 15HPTiO2 and SP showed similar fracture resistance teeth reduction (p > 0.05). All bleaching treatments reduced the fracture resistance compared to unbleached teeth (p endodontically-treated teeth, but there were no differences between each other. There are several internal bleaching protocols using hydrogen peroxide in different concentrations and activation methods. This study evaluated its effects on fracture resistance in endodontically-treated teeth.

  4. Physician-Patient Communication about Dietary Supplements

    Science.gov (United States)

    Tarn, Derjung M.; Paterniti, Debora A.; Good, Jeffrey S.; Coulter, Ian D.; Galliher, James M.; Kravitz, Richard L.; Karlamangla, Arun; Wenger, Neil S.

    2013-01-01

    Objective Describe the content and frequency of provider-patient dietary supplement discussions during primary care office visits. Methods Inductive content analysis of 1477 transcribed audio-recorded office visits to 102 primary care providers was combined with patient and provider surveys. Encounters were collected in Los Angeles, California (2009–2010), geographically-diverse practice settings across the United States (2004–2005), and Sacramento, CA (1998–1999). Results Providers discussed 738 dietary supplements during encounters with 357 patients (24.2% of all encounters in the data). They mentioned: 1) reason for taking the supplement for 46.5% of dietary supplements; 2) how to take the supplement for 28.2%; 3) potential risks for 17.3%; 4) supplement effectiveness for 16.7%; and 5) supplement cost or affordability for 4.2%. Of these five topics, a mean of 1.13 (SD=1.2) topics were discussed for each supplement. More topics were reviewed for non-vitamin non-mineral supplements (mean 1.47 (SD=1.2)) than for vitamin/mineral supplements (mean 0.99 (SD=1.1); psupplements are occurring, it is clear that more discussion might be needed to inform patient decisions about supplement use. Practice Implication Physicians could more frequently address topics that may influence patient dietary supplement use, such as the risks, effectiveness, and costs of supplements. PMID:23466249

  5. Colour stability of denture teeth submitted to different cleaning protocols and accelerated artificial aging.

    Science.gov (United States)

    Freire, T S; Aguilar, F G; Garcia, L da Fonseca Roberti; Pires-de-Souza, F de Carvalho Panzeri

    2014-03-01

    Acrylic resin is widely used for artificial teeth manufacturing due to several important characteristics; however, this material do not present acceptable colour stability over the course of time. This study evaluated the effect of different cleaning protocols and accelerated artificial aging on colour stability of denture teeth made of acrylic resin. Sixty denture teeth in dark and light shades were used, and separated according to the treatment to which they were submitted. Results demonstrated that colour stability of artificial teeth is influenced by the cleaning solution and artificial aging, being dark teeth more susceptible to colour alteration than lighter ones.

  6. Nutritional Supplements for Strength Power Athletes

    Science.gov (United States)

    Wilborn, Colin

    Over the last decade research involving nutritional supplementation and sport performance has increased substantially. Strength and power athletes have specific needs to optimize their performance. Nutritional supplementation cannot be viewed as a replacement for a balanced diet but as an important addition to it. However, diet and supplementation are not mutually exclusive, nor does one depend on the other. Strength and power athletes have four general areas of supplementation needs. First, strength athletes need supplements that have a direct effect on performance. The second group of supplements includes those that promote recovery. The third group comprises the supplements that enhance immune function. The last group of supplements includes those that provide energy or have a direct effect on the workout. This chapter reviews the key supplements needed to optimize the performance and training of the strength athlete.

  7. 25 CFR 533.2 - Time for submitting management contracts and amendments.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Time for submitting management contracts and amendments. 533.2 Section 533.2 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR MANAGEMENT CONTRACT PROVISIONS APPROVAL OF MANAGEMENT CONTRACTS § 533.2 Time for submitting management contracts and...

  8. Training Materials for Release 3

    DEFF Research Database (Denmark)

    Wake, Jo Dugstad; Hansen, Cecilie; Debus, Kolja

    This document, D7.4 – training materials for release 3, provides an overview of the training material for version 3 of the NEXT-TELL tools and methods. Previous documents submitted as part of work package 7, which is about teacher training, are D7.1 – Training Concept, D7.2 – Training Materials...... for Release 1 and D7.3 – Training Materials for Release 2. D7.4 builds on D7.1 and D7.2 and D7.3. D7.4 contains further development of previous work within WP7, essentially a revised theoretical approach to the teacher training, and expansion of the notion of tool training. The media in use have been expanded...

  9. Radio frequency identification (RFID) tagging for material tracking and future asset management : research project capsule.

    Science.gov (United States)

    2016-07-01

    Current Louisiana Department of Transportation and Development (DOTD) : practice allows multiple mixtures or materials to be submitted and subsequently : used during a highway construction project. Such materials include mechanically : stabilized ear...

  10. 46 CFR 50.20-30 - Alternative materials or methods of construction.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Alternative materials or methods of construction. 50.20... ENGINEERING GENERAL PROVISIONS Plan Submittal and Approval § 50.20-30 Alternative materials or methods of construction. (a) When new or alternative procedures, designs, or methods of construction are submitted for...

  11. Health Food Supplements (“Health Food” Highly Nutritious From Chlorella And Oil Catfish (Pangasius hypopthalmus

    Directory of Open Access Journals (Sweden)

    Syahrul Syahrul

    2016-12-01

    Full Text Available The utilization of microalgae as a food ingredient considered effective, because in addition to alternativefood sources also contains nutrients chlorella microalgae in particular is very good for health. This microalgaerich in protein (60.5%, fat (11%, carbohydrates (20.1%, water, dietary fiber, vitamins and minerals Besidesthese microalgae contain pigments (chlorophyll, tocopherol and the active component (antimicrobial andantioxidants. This is what underlies microalgae is very useful to be used as a source of raw materials ofhealth food supplements. Currently the health food supplements have become a necessity for people tomaintain their health in order to remain vibrant. This study aims to produce high nutritious health foodsupplements from raw material chlorella enriched with fish protein concentrate and oil catfish. The methodused in the manufacture of high nutritious health food supplement is a method of microencapsulation withdifferent formulations. The results showed that the best formulations based on the profile of amino acids,fatty acids and standards AAE per day especially essential fatty acids oleic and linoleic is formulation B(chlorella 2%, 1% fish oil and fish protein concentrate 1%.

  12. 20 CFR 10.801 - How are medical bills to be submitted?

    Science.gov (United States)

    2010-04-01

    ... employees, except for treatment and supplies provided by nursing homes, shall be supported by medical... separate bill shall be submitted when the employee is discharged from treatment or monthly, if treatment for the work-related condition is necessary for more than 30 days. (1)(i) Hospitals shall submit...

  13. 40 CFR 152.93 - Citation of a previously submitted valid study.

    Science.gov (United States)

    2010-07-01

    ... Data Submitters' Rights § 152.93 Citation of a previously submitted valid study. An applicant may demonstrate compliance for a data requirement by citing a valid study previously submitted to the Agency. The... the original data submitter, the applicant may cite the study only in accordance with paragraphs (b...

  14. 30 CFR 210.104 - Must I submit these production reports electronically?

    Science.gov (United States)

    2010-07-01

    ... MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.104 Must I submit these... Production Reporter Handbook for the most current reporting options, instructions, and security measures. The... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Must I submit these production reports...

  15. 27 CFR 73.31 - May I submit forms electronically to TTB?

    Science.gov (United States)

    2010-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.31 May I submit forms electronically to TTB? Yes; you may submit an electronic form, instead of a paper form, to satisfy any reporting...

  16. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 3: Appendices F-Q

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Hau, J. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations. This volume consists of appendices F-Q, which contain the analytical data from the site characterization.

  17. Degradation study of Durolon polycarbonate submitted to gamma radiation

    International Nuclear Information System (INIS)

    Miranda, A.; Sciani, V.

    1992-01-01

    The effect of gamma radiation from a cobalt 60 source in the 27000 Durolon polycarbonate irradiated with doses between 0,2 and 1000 kGy at 25 0 C was analyzed. For this reason the samples was submitted to the mechanical assay of tension, deformation and hardness and optical assay of transmittance. The obtained results show a good mechanical stability of the polycarbonate, when it was submitted to gamma irradiation in doses up to 20 kGy. (C.G.C.). 05 refs., 04 figs

  18. 31 CFR 103.81 - Submitting requests.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Submitting requests. 103.81 Section 103.81 Money and Finance: Treasury Regulations Relating to Money and Finance FINANCIAL RECORDKEEPING... which the request is made. (b) A request filed by a corporation shall be signed by a corporate officer...

  19. Dietary supplements for football.

    Science.gov (United States)

    Hespel, P; Maughan, R J; Greenhaff, P L

    2006-07-01

    Physical training and competition in football markedly increase the need for macro- and micronutrient intake. This requirement can generally be met by dietary management without the need for dietary supplements. In fact, the efficacy of most supplements available on the market is unproven. In addition, players must be cautious of inadequate product labelling and supplement impurities that may cause a positive drug test. Nonetheless, a number of dietary supplements may beneficially affect football performance. A high endurance capacity is a prerequisite for optimal match performance, particularly if extra time is played. In this context, the potential of low-dose caffeine ingestion (2 - 5 mg . kg body mass(-1)) to enhance endurance performance is well established. However, in the case of football, care must be taken not to overdose because visual information processing might be impaired. Scoring and preventing goals as a rule requires production of high power output. Dietary creatine supplementation (loading dose: 15 - 20 g . day(-1), 4 - 5 days; maintenance dose: 2 - 5 g g . day(-1)) has been found to increase muscle power output, especially during intermittent sprint exercises. Furthermore, creatine intake can augment muscle adaptations to resistance training. Team success and performance also depend on player availability, and thus injury prevention and health maintenance. Glucosamine or chondroitin may be useful in the treatment of joint pain and osteoarthritis, but there is no evidence to support the view that the administration of these supplements will be preventative. Ephedra-containing weight-loss cocktails should certainly be avoided due to reported adverse health effects and positive doping outcomes. Finally, the efficacy of antioxidant or vitamin C intake in excess of the normal recommended dietary dose is equivocal. Responses to dietary supplements can vary substantially between individuals, and therefore the ingestion of any supplement must be assessed

  20. Enhanced acetone-butanol-ethanol production from lignocellulosic hydrolysates by using starchy slurry as supplement.

    Science.gov (United States)

    Yang, Ming; Kuittinen, Suvi; Vepsäläinen, Jouko; Zhang, Junhua; Pappinen, Ari

    2017-11-01

    This study aims to improve acetone-butanol-ethanol production from the hydrolysates of lignocellulosic material by supplementing starchy slurry as nutrients. In the fermentations of glucose, xylose and the hydrolysates of Salix schwerinii, the normal supplements such as buffer, minerals, and vitamins solutions were replaced with the barley starchy slurry. The ABE production was increased from 0.86 to 14.7g/L by supplementation of starchy slurry in the fermentation of xylose and the utilization of xylose increased from 29% to 81%. In the fermentations of hemicellulosic and enzymatic hydrolysates from S. schwerinii, the ABE yields were increased from 0 and 0.26 to 0.35 and 0.33g/g sugars, respectively. The results suggested that the starchy slurry supplied the essential nutrients for ABE fermentation. The starchy slurry as supplement could improve the ABE production from both hemicellulosic and cellulosic hydrolysate of lignocelluloses, and it is particularly helpful for enhancing the utilization of xylose from hemicelluloses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Nuclear waste information in supplements of local newspapers

    International Nuclear Information System (INIS)

    Ryhaenen, Veijo

    1995-01-01

    Full text: The utility Teollisuuden Voima Oy (TVO) is conducting site investigations in Finland to select a final disposal site for spent nuclear fuel. Site selection studies, including deep drillings and other field investigations, have been carried out in different parts of the country since 1987. Now there are three areas in which detailed studies are continued. The programme aims at site selection in the year 2000. Before the construction of the final disposal facility can be started around the year 2010 a precondition in the Finnish legislation is that the council of the local municipality accepts the facility. Hence, an essential task is to distribute information of the studies and of the principles of final disposal to the local decision-makers and public. Information work has an important role already now in order to make people familiar with the long-term project and to build confidence on the safety of final disposal. TVO's information programme includes several types of actions to different target groups, such as press conferences, contact group meetings, open houses, exhibitions, lectures to different groups, visits to the drilling sites and to the existing nuclear waste facilities as well as use of various written material. In January 1994 a new method was applied in the distribution of TVO's written information directly to local public. Four-page supplements were prepared to the local newspapers to inform public of the stage of the site investigations and other topical issues. After that, new supplements have been published in six months intervals. Own supplements have been made for different municipalities in which the candidate areas are situated. The form of the supplement is same as that of the newspaper. As a matter of fact, TVO's information forms a special advertising section in a single issue of a newspaper. The topics handled in the supplements are for example present status of the local bedrock studies, other topical information of TVO

  2. Herbs, Supplements and Alternative Medicines

    Science.gov (United States)

    ... A A Listen En Español Herbs, Supplements and Alternative Medicines It is best to get vitamins and minerals ... this section Medication Other Treatments Herbs, Supplements, and Alternative Medicines Types of Dietary Supplements Side Effects and Drug ...

  3. Safe transport of radioactive material. Second edition

    International Nuclear Information System (INIS)

    1996-01-01

    In 1991, the International Atomic Energy Agency published Training Course Series No. 1 (TCS-1), a training manual that provides in 20 chapters a detailed discussion of the background, philosophy, technical bases and requirements and implementation aspects of the Regulations for the Safe Transport of Radioactive Material. The Transport Regulations are widely implemented by the IAEA's Member States and are also used as the bases for radioactive material transport requirements of modal organisations such as the International Maritime Organization and the International Civil Aviation Organization. This document is a supplement of TCS-1 to provide additional material in the form of learning aids and new exercises, that have been developed with the use of TCS-1 at succeeding IAEA training courses. The learning aids in the first part of the supplement are hitherto unpublished material that provide detailed guidance useful in solving the exercises presented in the second part. Solutions to the exercises are on field at the IAEA Secretariat and are available by arrangement to lectures presenting IAEA training courses. 4 refs, 1 fig., 6 tabs

  4. Why US children use dietary supplements

    Science.gov (United States)

    Bailey, Regan L.; Gahche, Jaime J.; Thomas, Paul R.; Dwyer, Johanna T.

    2013-01-01

    Background: Dietary supplements are used by one-third of children. We examined motivations for supplement use in children, the types of products used by motivations, and the role of physicians and health care practitioners in guiding choices about supplements. Methods: We examined motivations for dietary supplement use reported for children (from birth to 19 y of age; n = 8,245) using the National Health and Nutrition Examination Survey 2007–2010. Results: Dietary supplements were used by 31% of children; many different reasons were given as follows: to “improve overall health” (41%), to “maintain health” (37%), for “supplementing the diet” (23%), to “prevent health problems” (20%), and to “boost immunity” (14%). Most children (~90%) who use dietary supplements use a multivitamin–mineral or multivitamin product. Supplement users tend to be non-Hispanic white, have higher family incomes, report more physical activity, and have health insurance. Only a small group of supplements used by children (15%) were based on the recommendation of a physician or other health care provider. Conclusion: Most supplements used by children are not under the recommendation of a health care provider. The most common reasons for use of supplements in children are for health promotion, yet little scientific data support this notion in nutrient-replete children. PMID:24002333

  5. 40 CFR 63.8818 - What reports must I submit and when?

    Science.gov (United States)

    2010-07-01

    ... other daily calibration checks. (f) The compliance report for a new or reconstructed flame lamination... not included in the list submitted with the Notification of Compliance Status in § 63.8816(h) (1), an... approved a different schedule for submission of reports under § 63.10(a), you must submit each compliance...

  6. Annual Statistical Supplement, 2002

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2002 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  7. Annual Statistical Supplement, 2010

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2010 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  8. Annual Statistical Supplement, 2007

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2007 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  9. Annual Statistical Supplement, 2001

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2001 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  10. Annual Statistical Supplement, 2016

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2016 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  11. Annual Statistical Supplement, 2011

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2011 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  12. Annual Statistical Supplement, 2005

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2005 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  13. Annual Statistical Supplement, 2015

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2015 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  14. Annual Statistical Supplement, 2003

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2003 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  15. Annual Statistical Supplement, 2017

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2017 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  16. Annual Statistical Supplement, 2008

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2008 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  17. Annual Statistical Supplement, 2014

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2014 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  18. Annual Statistical Supplement, 2004

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2004 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  19. Annual Statistical Supplement, 2000

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2000 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  20. Annual Statistical Supplement, 2009

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2009 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  1. Annual Statistical Supplement, 2006

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2006 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  2. 2002 Microgravity Materials Science Conference

    Science.gov (United States)

    Gillies, Donald (Editor); Ramachandran, Narayanan (Editor); Murphy, Karen (Editor); McCauley, Dannah (Editor); Bennett, Nancy (Editor)

    2003-01-01

    The 2002 Microgravity Materials Science Conference was held June 25-26, 2002, at the Von Braun Center, Huntsville, Alabama. Organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Physical Sciences Research Division, NASA Headquarters, and hosted by NASA Marshall Space Flight Center and member institutions under the Cooperative Research in Biology and Materials Science (CORBAMS) agreement, the conference provided a forum to review the current research and activities in materials science, discuss the envisioned long-term goals, highlight new crosscutting research areas of particular interest to the Physical Sciences Research Division, and inform the materials science community of research opportunities in reduced gravity. An abstracts book was published and distributed at the conference to the approximately 240 people attending, who represented industry, academia, and other NASA Centers. This CD-ROM proceedings is comprised of the research reports submitted by the Principal Investigators in the Microgravity Materials Science program.

  3. Evaluation Of Supplemental Pre-Treatment Development Requirements To Meet TRL 6: Rotary Microfiltration

    International Nuclear Information System (INIS)

    Huber, H.J.

    2011-01-01

    In spring 2011, the Technology Maturation Plan (TMP) for the Supplemental Treatment Project (RPP-PLAN-49827, Rev. 0), Technology Maturation Plan for the Treatment Project (T4S01) was developed. This plan contains all identified actions required to reach technical maturity for a field-deployable waste feed pretreatment system. The supplemental pretreatment system has a filtration and a Cs-removal component. Subsequent to issuance of the TMP, rotary microfiltration (RMF) has been identified as the prime filtration technology for this application. The prime Cs-removal technology is small column ion exchange (ScIX) using spherical resorcinol formaldehyde (sRF) as the exchange resin. During fiscal year 2011 (FY2011) some of the tasks identified in the TMP have been completed. As of September 2011, the conceptual design package has been submitted to DOE as part of the critical decision (CD-1) process. This document describes the remaining tasks identified in the TMP to reach technical maturity and evaluates the validity of the proposed tests to fill the gaps as previously identified in the TMP. The potential vulnerabilities are presented and the completed list of criteria for the DOE guide DOE G 413.3-4 different technology readiness levels are added in an attachment. This evaluation has been conducted from a technology development perspective - all programmatic and manufacturing aspects were excluded from this exercise. Compliance with the DOE G 413.3-4 programmatic and manufacturing requirements will be addressed directly by the Treatment Project during the course of engineering design. The results of this evaluation show that completion of the proposed development tasks in the TMP are sufficient to reach TRL 6 from a technological point of view. The tasks involve actual waste tests using the current baseline configuration (2nd generation disks, 40 psi differential pressure, 30 C feed temperature) and three different simulants - the PEP, an AP-Farm and an S

  4. 7 CFR 3406.12 - Program application materials-teaching.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Program application materials-teaching. 3406.12... GRANTS PROGRAM Preparation of a Teaching Proposal § 3406.12 Program application materials—teaching... program, and the forms needed to prepare and submit teaching grant applications under the program. ...

  5. Prostate-Specific Natural Health Products (Dietary Supplements) Radiosensitize Normal Prostate Cells

    International Nuclear Information System (INIS)

    Hasan, Yasmin; Schoenherr, Diane; Martinez, Alvaro A.; Wilson, George D.; Marples, Brian

    2010-01-01

    Purpose: Prostate-specific health products (dietary supplements) are taken by cancer patients to alleviate the symptoms linked with poor prostate health. However, the effect of these agents on evidence-based radiotherapy practice is poorly understood. The present study aimed to determine whether dietary supplements radiosensitized normal prostate or prostate cancer cell lines. Methods and Materials: Three well-known prostate-specific dietary supplements were purchased from commercial sources available to patients (Trinovin, Provelex, and Prostate Rx). The cells used in the study included normal prostate lines (RWPE-1 and PWR-1E), prostate tumor lines (PC3, DU145, and LNCaP), and a normal nonprostate line (HaCaT). Supplement toxicity was assessed using cell proliferation assays [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] and cellular radiosensitivity using conventional clonogenic assays (0.5-4Gy). Cell cycle kinetics were assessed using the bromodeoxyuridine/propidium iodide pulse-labeling technique, apoptosis by scoring caspase-3 activation, and DNA repair by assessing γH2AX. Results: The cell growth and radiosensitivity of the malignant PC3, DU145, and LNcaP cells were not affected by any of the dietary prostate supplements (Provelex [2μg/mL], Trinovin [10μg/mL], and Prostate Rx [50 μg/mL]). However, both Trinovin (10μg/mL) and Prostate Rx (6μg/mL) inhibited the growth rate of the normal prostate cell lines. Prostate Rx increased cellular radiosensitivity of RWPE-1 cells through the inhibition of DNA repair. Conclusion: The use of prostate-specific dietary supplements should be discouraged during radiotherapy owing to the preferential radiosensitization of normal prostate cells.

  6. Supplement consumption in body builder athletes

    Science.gov (United States)

    Karimian, Jahangir; Esfahani, Parivash Shekarchizadeh

    2011-01-01

    BACKGROUND: Widespread use of supplements is observed among world athletes in different fields. The aim of this study was to estimate the prevalence and determinants of using supplements among body builder athletes. METHODS: This cross-sectional study was conducted on 250 men and 250 women from 30 different bodybuilding clubs. Participants were asked to complete a self-administered standardized anonymous check-list. RESULTS: Forty nine percent of the respondents declared supplement use. Men were more likely to take supplements than women (86.8% vs. 11.2%, p = 0.001). Reasons for using supplements were reported to be for health (45%), enhancing the immune system (40%) and improving athletic performance (25%). Most athletes (72%) had access to a nutritionist but underused this resource. Coaches (65%) had the greatest influence on supplementation practices followed by nutritionists (30%) and doctors (25%) after them. CONCLUSIONS: The prevalence of supplement use among bodybuilders was high. Sex, health-related issues and sport experts were determinant factors of supplement use. PMID:22973330

  7. Assessing patients' attitudes towards dietary supplements.

    Science.gov (United States)

    Wierzejska, Regina; Jarosz, Mirosław; Siuba, Magdalena; Rambuszek, Michał

    2014-01-01

    There is currently many over the counter products on the market that exert nutritional or physiological effects on the human body. The differences between dietary supplements and non-prescription drugs are however poorly understood by the average consumer and may thus affect their expectations as to the desired effect produced on the body. To evaluate patients' knowledge and attitudes towards dietary supplements as compared to non-prescription drugs. Subjects were 335 patients of the Mazowiecki Voivodeship Hospital in Warsaw, Poland. The data were collected from a face-to-face interview using a single and multiple choice questionnaire with 10 questions on dietary supplements. Statistical analysis used the Chi-square (χ2) test. The majority of respondents were found to be familiar with the term 'dietary supplements', but had difficulties in classifying these products into appropriate categories. Over 55% do not consider dietary supplements to be foodstuffs and more than 40% considered such products to be drugs. Most respondents thought that the main purpose of taking dietary supplements is to improve nutrition, but over one third expected them to also treat disease. Over 70% declared taking notice to which category the non-prescription products they bought belongs to ie. whether non-prescription drugs (medicinal products) or dietary supplements. Many patients mistakenly believe that dietary supplements are drugs and can be used to treat disease and health disorders. dietary supplements, opinion on dietary supplements, nutrition, dietary supplement vs. medicinal product.

  8. Supplements in human islet culture: human serum albumin is inferior to fetal bovine serum.

    Science.gov (United States)

    Avgoustiniatos, Efstathios S; Scott, William E; Suszynski, Thomas M; Schuurman, Henk-Jan; Nelson, Rebecca A; Rozak, Phillip R; Mueller, Kate R; Balamurugan, A N; Ansite, Jeffrey D; Fraga, Daniel W; Friberg, Andrew S; Wildey, Gina M; Tanaka, Tomohiro; Lyons, Connor A; Sutherland, David E R; Hering, Bernhard J; Papas, Klearchos K

    2012-01-01

    Culture of human islets before clinical transplantation or distribution for research purposes is standard practice. At the time the Edmonton protocol was introduced, clinical islet manufacturing did not include culture, and human serum albumin (HSA), instead of fetal bovine serum (FBS), was used during other steps of the process to avoid the introduction of xenogeneic material. When culture was subsequently introduced, HSA was also used for medium supplementation instead of FBS, which was typically used for research islet culture. The use of HSA as culture supplement was not evaluated before this implementation. We performed a retrospective analysis of 103 high-purity islet preparations (76 research preparations, all with FBS culture supplementation, and 27 clinical preparations, all with HSA supplementation) for oxygen consumption rate per DNA content (OCR/DNA; a measure of viability) and diabetes reversal rate in diabetic nude mice (a measure of potency). After 2-day culture, research preparations exhibited an average OCR/DNA 51% higher (p < 0.001) and an average diabetes reversal rate 54% higher (p < 0.05) than clinical preparations, despite 87% of the research islet preparations having been derived from research-grade pancreata that are considered of lower quality. In a prospective paired study on islets from eight research preparations, OCR/DNA was, on average, 27% higher with FBS supplementation than that with HSA supplementation (p < 0.05). We conclude that the quality of clinical islet preparations can be improved when culture is performed in media supplemented with serum instead of albumin.

  9. 75 FR 66686 - Defense Federal Acquisition Regulation Supplement; Balance of Payments Program Exemption for...

    Science.gov (United States)

    2010-10-29

    ... Federal Acquisition Regulation Supplement; Balance of Payments Program Exemption for Commercial... Balance of Payments Program for construction material that is commercial information technology. DATES... the Balance of Payments Program for commercial information technology to be used in overseas...

  10. Final safety evaluation report related to the certification of the Advanced Boiling Water Reactor design. Supplement 1

    International Nuclear Information System (INIS)

    1997-05-01

    This report supplements the final safety evaluation report (FSER) for the US Advanced Boiling Water Reactor (ABWR) standard design. The FSER was issued by the US Nuclear Regulatory Commission (NRC) staff as NUREG-1503 in July 1994 to document the NRC staff's review of the US ABWR design. The US ABWR design was submitted by GE Nuclear Energy (GE) in accordance with the procedures of Subpart B to Part 52 of Title 10 of the Code of Federal Regulations. This supplement documents the NRC staff's review of the changes to the US ABWR design documentation since the issuance of the FSER. GE made these changes primarily as a result of first-of-a-kind-engineering (FOAKE) and as a result of the design certification rulemaking for the ABWR design. On the basis of its evaluations, the NRC staff concludes that the confirmatory issues in NUREG-1503 are resolved, that the changes to the ABWR design documentation are acceptable, and that GE's application for design certification meets the requirements of Subpart B to 10 CFR Part 52 that are applicable and technically relevant to the US ABWR design

  11. Final safety evaluation report related to the certification of the Advanced Boiling Water Reactor design. Supplement 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    This report supplements the final safety evaluation report (FSER) for the US Advanced Boiling Water Reactor (ABWR) standard design. The FSER was issued by the US Nuclear Regulatory Commission (NRC) staff as NUREG-1503 in July 1994 to document the NRC staff`s review of the US ABWR design. The US ABWR design was submitted by GE Nuclear Energy (GE) in accordance with the procedures of Subpart B to Part 52 of Title 10 of the Code of Federal Regulations. This supplement documents the NRC staff`s review of the changes to the US ABWR design documentation since the issuance of the FSER. GE made these changes primarily as a result of first-of-a-kind-engineering (FOAKE) and as a result of the design certification rulemaking for the ABWR design. On the basis of its evaluations, the NRC staff concludes that the confirmatory issues in NUREG-1503 are resolved, that the changes to the ABWR design documentation are acceptable, and that GE`s application for design certification meets the requirements of Subpart B to 10 CFR Part 52 that are applicable and technically relevant to the US ABWR design.

  12. 75 FR 8364 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2010-02-24

    ... on proposed data collection projects, the Centers for Disease Control and Prevention (CDC) will... data base containing identifying death record information submitted annually to NCHS by all the State...] Proposed Data Collections Submitted for Public Comment and Recommendations In compliance with the...

  13. 30 CFR 256.12 - Supplemental sales.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Supplemental sales. 256.12 Section 256.12..., General § 256.12 Supplemental sales. (a) The Secretary may conduct a supplemental sale in accordance with the provisions of this section. (b) Supplemental sales shall be governed by the regulations in this...

  14. 30 CFR 254.7 - How do I submit my response plan to the MMS?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my response plan to the MMS... do I submit my response plan to the MMS? You must submit the number of copies of your response plan that the appropriate MMS regional office requires. If you prefer to use improved information technology...

  15. Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans.

    Science.gov (United States)

    d'Alessio, Patrizia A; Ostan, Rita; Bisson, Jean-François; Schulzke, Joerg D; Ursini, Matilde V; Béné, Marie C

    2013-07-10

    To further explore the anti-inflammatory properties of d-Limonene. A rat model was used to compare evolution of TNBS (2,5,6-trinitrobenzene sulfonic acid)-induced colitis after oral feeding with d-Limonene compared to ibuprofen. Peripheral levels of TNF-α (Tumor Necrosis Factor alpha) were assessed in all animals. Cell cultures of fibroblasts and enterocytes were used to test the effect of d-Limonene respectively on TNFα-induced NF-κB (nuclear factor-kappa B) translocation and epithelial resistance. Finally, plasmatic inflammatory markers were examined in an observational study of diet supplementation with d-Limonene-containing orange peel extract (OPE) in humans. Administered per os at a dose of 10mg/kg p.o., d-Limonene induced a significant reduction of intestinal inflammatory scores, comparable to that induced by ibuprofen. Moreover, d-Limonene-fed rats had significantly lowered serum concentrations of TNF-α compared to untreated TNBS-colitis rats. The anti-inflammatory effect of d-Limonene also involved inhibition of TNFα-induced NF-κB translocation in fibroblast cultures. The application of d-Limonene on colonic HT-29/B6 cell monolayers increased epithelial resistance. Finally, inflammatory markers, especially peripheral IL-6, markedly decreased upon OPE supplementation of elderly healthy subjects submitted or not to 56 days of dietary supplementation with OPE. In conclusion, d-Limonene indeed demonstrates significant anti-inflammatory effects both in vivo and in vitro. Protective effects on the epithelial barrier and decreased cytokines are involved, suggesting a beneficial role of d-Limonene as diet supplement in reducing inflammation. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. Nutritional Supplements for Endurance Athletes

    Science.gov (United States)

    Rasmussen, Christopher J.

    Athletes engaged in heavy endurance training often seek additional nutritional strategies to help maximize performance. Specific nutritional supplements exist to combat certain factors that limit performance beginning with a sound everyday diet. Research has further demonstrated that safe, effective, legal supplements are in fact available for today's endurance athletes. Several of these supplements are marketed not only to aid performance but also to combat the immunosuppressive effects of intense endurance training. It is imperative for each athlete to research the legality of certain supplements for their specific sport or event. Once the legality has been established, it is often up to each individual athlete to decipher the ethics involved with ingesting nutritional supplements with the sole intent of improving performance.

  17. Education for AIDS Prevention: Bibliography--Supplement No. 1=Education pour la prevention du SIDA: Bibliographie--Supplement No. 1=Educacion para la Prevencion del SIDA: Bibliografia--Suplemento No. 1.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Documentation and Information Service.

    This supplement to the Education for AIDS Prevention Bibliography provides a list of titles received by ASERC (AIDS School Education Resource Centre) from August 1991 to December 1992, consisting mainly of educational material for schools. It also includes documents of a more general nature on AIDS and AIDS prevention. ASERC is a documentation…

  18. Effects of supplemental vitamin C (Ascorbic Acid) on the growth and ...

    African Journals Online (AJOL)

    Four different diets each containing 37.4% crude protein were formulated from locally available feed materials to contain 0 (control), 23, 46 and 92 mg/Kg supplemental Ascorbic acid (AA) respectively. Catfish with average weight of 2 - 6g were stocked and fed twice daily to satiation initially with Coppens fish feed for the first ...

  19. 21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

  20. Food supplements: survey of the ASL TO3.

    Science.gov (United States)

    Valfrè, R; Bioletti, L; Spagna, S; Rolle, M; Zucaro, D; Vietti, F; Laurenti, P

    2014-01-01

    supplements at gyms located on the territory of ASLTO3: 59 gyms are available on territory, but only in one of them supplements are sold. Some customers of these gyms have filled a questionnaire concerning the consumption of supplements. The processing of the questionnaires showed that 27% of respondents in the past 2 years used only occasionally food supplements. For 42% of the subjects the use of these products was to achieve weight loss, for 33% for athletes and 17% have used specific products in the case of particular physiological situations such as pregnancy and lactation. The reasons that lead to the use of dietary supplements, in all cases, are attributed to the improvement of health status. In addition, in 50% of cases the pharmacist has led to the use of these products or, alternatively, friends and relatives. The general practitioner is often not informed even in case of disturbances introduced after their use (seen in 8% of our sample). The majority of the sample (58%) said that they had benefited from the use of supplements and they are aware (68%) that there could be contraindications. A greater knowledge of the topic, with attention focused on the entire supply chain of the product, is essential to ensure the safety of consumers in the use of food supplements. For these reasons a more detailed check on the procedure is essential: selection and verification of suppliers (especially for raw materials coming from Eastern countries, because they are not subjected to a thorough inspection); traceability of products marketed; correspondence between manufactured and authorized products. Finally, promote an awareness campaign at all levels is necessary, including general practitioners for a conscious purchase.

  1. 25 CFR 1000.21 - When does a Tribe/Consortium have a “material audit exception”?

    Science.gov (United States)

    2010-04-01

    ...-Governance Eligibility § 1000.21 When does a Tribe/Consortium have a “material audit exception”? A Tribe/Consortium has a material audit exception if any of the audits that it submitted under § 1000.17(c...

  2. 47 CFR 61.86 - Supplements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Supplements. 61.86 Section 61.86... Rules for Tariff Publications of Dominant and Nondominant Carriers § 61.86 Supplements. A carrier may not file a supplement except to suspend or cancel a tariff publication, or to defer the effective date...

  3. The Use Potential of Traditional Building Materials for the Realization of Structures by Modern Methods of Construction

    Science.gov (United States)

    Spišáková, Marcela; Mačková, Daniela

    2015-11-01

    The sustainable building has taken off in recent years with many investors looking for new and different methods of construction. The traditional building materials can be made out of natural materials, while others can help to lower energy costs of the occupant once built. Regardless of what the goal of the investor is, traditional building materials and their use is on the rise. The submitted paper provides an overview of natural building materials and possible modern building systems using these construction materials. Based on the questionnaire survey is defined the use potential of traditional building materials for the realization of the construction by methods of modern constructions and then are determined the drivers and barriers of traditional materials through using modern methods of construction. Considering the analysis of the achieved results, we can identify the gaps in the construction market in Slovakia and also to assess the perception of potential investors in the field of traditional building materials use, which is the purpose of submitted paper.

  4. Materials qualification for nuclear power plants

    International Nuclear Information System (INIS)

    Braconi, F.

    1987-01-01

    The supply of materials to be used in the fabrication of components submitted to pressure destined to Atucha II nuclear power plant must fulfill the quality assurance requirements in accordance with the international standards. With the aim of promoting the national participation in CNA II, ENACE had the need to adapt these requirements to the national industry conditions and to the availability of official entities' qualification and inspection. As a uniform and normalized assessment for the qualification of materials did not exist in the country, ENACE had to develop a materials suppliers qualification system. This paper presents a suppliers qualification procedure, its application limits and the alternative procedures for the acceptance of individual stock and for the stock materials purchase. (Author)

  5. 49 CFR Appendix II to Part 805 - Employees Required To Submit Statements

    Science.gov (United States)

    2010-10-01

    ...—Employees Required To Submit Statements Statements of employment and financial interests are required of the... 49 Transportation 7 2010-10-01 2010-10-01 false Employees Required To Submit Statements II...) Office of the managing director: (1) Legislative affairs officer. (2) Program analysis officer. (d...

  6. Children and Dietary Supplements

    Science.gov (United States)

    ... Clinical Digest for health professionals Children and Dietary Supplements Share: September 2012 © Matthew Lester Research has shown that many children use herbs and other dietary supplements. However, there are little data available on their ...

  7. Materials for the nuclear - Modelling and simulation of structure materials

    International Nuclear Information System (INIS)

    Berthoud, Georges; Ducros, Gerard; Feron, Damien; Guerin, Yannick; Latge, Christian; Limoge, Yves; Santarini, Gerard; Seiler, Jean-Marie; Vernaz, Etienne; Cappelaere, Chantal; Andrieux, Catherine; Athenes, Manuel; Baldinozzi, Guido; Bechade, Jean-Luc; Bonin, Bernard; Boutard, Jean-Louis; Brechet, Yves; Bruneval, Fabien; Carassou, Sebastien; Castelier, Etienne; Chartier, Alain; Clouet, Emmanuel; Marinica, Mihai-Cosmin; Crocombette, Jean-Paul; Dupuy, Laurent; Forget, Pierre; Fu, Chu Chun; Garnier, Jerome; Gelebart, Lionel; Henry, Jean; Jourdan, Thomas; Luneville, Laurence; Marini, Bernard; Meslin, Estelle; Nastar, Maylise; Onimus, Fabien; Poussard, Christophe; Proville, Laurent; Ribis, Joel; Robertson, Christian; Rodney, David; Roma, Guido; Sauzay, Maxime; Simeone, David; Soisson, Frederic; Tanguy, Benoit; Toffolon-Masclet, Caroline; Trocellier, Patrick; Van Brutzel, Laurent; Ventelon, Usa; Vincent, Ludovic; Willaime, Francois; Yvon, Pascal; Behar, Christophe; Provitina, Olivier; Lecomte, Michael; Forestier, Alain; Bender, Alexandra; Parisot, Jean-Francois; Finot, Pierre

    2016-01-01

    This collective publication proposes presentations of scientific approaches implemented to model and simulate the behaviour of materials submitted to irradiation, of associated experimental methods, and of some recent important results. After an introduction presenting the various materials used in different types of nuclear reactors (PWR, etc.), the effects of irradiation at the macroscopic or at the atomic scale, and the multi-scale (time and space) approach to the modelling of these materials, a chapter proposes an overview of modelling tools: multi-scale approach, electronic calculations for condensed matter, inter-atomic potentials, molecular dynamics simulation, thermodynamic and medium force potentials, phase diagrams, simulation of primary damages in reactor materials, kinetic models, dislocation dynamics, production of microstructures for simulation, crystalline visco-plasticity, homogenization methods in continuum mechanics, local approach and probabilistic approach in material fracture. The next part presents tools for experimental validation: tools for microscopic characterization or for mechanical characterization, experimental reactors and tests in atomic pile, tools for irradiation by charged particles. The next chapters presents different examples of thermodynamic and kinetic modelling in the case of various alloys (zirconium alloys, iron-chromium alloys, silicon carbide, austenitic alloys), of plasticity and failure modelling

  8. Thermal Expansion Properties of Aerospace Materials

    Science.gov (United States)

    Green, E. F.

    1969-01-01

    Thermal expansion properties of materials used in aerospace systems are compiled into a single handbook. The data, derived from experimental measurements supplemented by information from literature sources, are presented in charts and tables arranged in two sections, covering cryogenic and elevated temperatures.

  9. FY01 Supplemental Science and Performance Analyses, Volume 1: Scientific Bases and Analyses, Part 1 and 2

    International Nuclear Information System (INIS)

    Dobson, David

    2001-01-01

    The U.S. Department of Energy (DOE) is considering the possible recommendation of a site at Yucca Mountain, Nevada, for development as a geologic repository for the disposal of high-level radioactive waste and spent nuclear fuel. To facilitate public review and comment, in May 2001 the DOE released the Yucca Mountain Science and Engineering Report (S and ER) (DOE 2001 [DIRS 153849]), which presents technical information supporting the consideration of the possible site recommendation. The report summarizes the results of more than 20 years of scientific and engineering studies. A decision to recommend the site has not been made: the DOE has provided the S and ER and its supporting documents as an aid to the public in formulating comments on the possible recommendation. When the S and ER (DOE 2001 [DIRS 153849]) was released, the DOE acknowledged that technical and scientific analyses of the site were ongoing. Therefore, the DOE noted in the Federal Register Notice accompanying the report (66 FR 23 013 [DIRS 155009], p. 2) that additional technical information would be released before the dates, locations, and times for public hearings on the possible recommendation were announced. This information includes: (1) the results of additional technical studies of a potential repository at Yucca Mountain, contained in this FY01 Supplemental Science and Performance Analyses: Vol. 1, Scientific Bases and Analyses; and FY01 Supplemental Science and Performance Analyses: Vol. 2, Performance Analyses (McNeish 2001 [DIRS 155023]) (collectively referred to as the SSPA) and (2) a preliminary evaluation of the Yucca Mountain site's preclosure and postclosure performance against the DOE's proposed site suitability guidelines (10 CFR Part 963 [64 FR 67054] [DIRS 124754]). By making the large amount of information developed on Yucca Mountain available in stages, the DOE intends to provide the public and interested parties with time to review the available materials and to formulate

  10. 28 CFR 14.4 - Administrative claims; evidence and information to be submitted.

    Science.gov (United States)

    2010-07-01

    ... bearing on either the responsibility of the United States for the death or the damages claimed. (b... submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other competent evidence...

  11. 20 CFR 669.510 - What planning documents must an NFJP grantee submit?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning documents must an NFJP grantee submit? 669.510 Section 669.510 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Accountability, Planning and Waiver Provision § 669.510 What planning documents must an NFJP grantee submit? Each...

  12. Effects of Submaximal Endurance Training and Vitamin D3 Supplementation on Pain Threshold in Diabetic Rats

    Directory of Open Access Journals (Sweden)

    S. Jalal Taherabadi

    2013-07-01

    Full Text Available Background: According to beneficial effects of endurance training and vitamin D3 in diabetes mellitus, purpose of this study is effects submaximal endurance training and vitamin D3 supplementation on pain threshold in streptozotocin induced diabetic rats.Materials and Methods: Male Wistar rats (250±20 g, N=40 were made diabetic by streptozotocin (60 mg/kg, subcutaneously. 72 h after injection diabetes induction was confirmed by tail vein blood glucose concentration (>300 mg/dl. Then animals were divided to five groups: diabetic control (DC, diabetic trained (DT, diabetic -vitamin D (DD, diabetic trained and vitamin D (DTD, and control (C. Animals were submitted to endurance training by treadmill and vitamin D3 treatment (twice aweek, intrapretonally for 4 weeks. 48 h after at the end of exercise and treatment protocol, we used tail-flick to assess the effects of training and vitamin D3 on thermal pain threshold. We used one way ANOVA statistical analysis to compare differences between groups, significance level of p<0.05 was considered.Results: Diabetic induced hyperalgesia were decreased significantly by vitamin D but not 4 weeks endurance exercise training. Concurrent effects of training and vitamin D on thermal pain threshold were not significantly higher than vitamin D effects alone.Conclusion: It is concluded that vitamin D administration given at the time of diabetes induction may be able to restore thermal hyperalgesia. But effects of endurance exercise training needs to more investigation in diabetic rats.

  13. Performance of Chicks Submitted to Fasting Post-Hatching and with Maltodextrine Supplementing to Diet as Hydrating and Energetic Additive

    Directory of Open Access Journals (Sweden)

    CA Machado

    Full Text Available ABSTRACT This study aimed to evaluate the effect of maltodextrin on performance of chicks passed through four fasting periods. A completely randomized design was performed, consisting of three treatments (1 - control, 2 - 4% saccharose; 3-4% maltodextrin 20 and four fasting periods after hatching (0, 12, 24 and 36 hours with four replications, totaling 1920 birds of both sexes. The studied variables were: water intake in the first 12 hours, average food intake, average body weight and real feed conversion. Data was submitted to analysis of variance and means were compared with each other by Dunnett test at 5% significance. The use of additives and imposing of different fasting periods did not influence the performance at 42 days old. Therefore, fasted chicks consumed significantly more water. At 7 days old, chicks fasted showed higher body weight and higher feed intake, however, the viability did not suffer any influence, the weight remained higher after 21days with the fast imposition and there was no influence on other variables. There was no effect of fasting on broiler chiken's performance at 42 days old. The inclusion of sucrose and maltodextrin to drinking water stimulated the chick´s water intake and provided higher viability after seven days old.

  14. 76 FR 71926 - Defense Federal Acquisition Regulation Supplement: Applicability of Hexavalent Chromium Policy to...

    Science.gov (United States)

    2011-11-21

    ... 0750-AH39 Defense Federal Acquisition Regulation Supplement: Applicability of Hexavalent Chromium... the use of materials containing hexavalent chromium. DATES: Comment Date: Comments on the proposed... human health and environmental risks related to the use of hexavalent chromium. Hexavalent chromium is a...

  15. Effect of supplementing crop substrate with defatted pistachio meal on Agaricus bisporus and Pleurotus ostreatus production.

    Science.gov (United States)

    Pardo-Giménez, Arturo; Catalán, Luis; Carrasco, Jaime; Álvarez-Ortí, Manuel; Zied, Diego; Pardo, José

    2016-08-01

    This work assesses the agronomic performance of defatted pistachio meal, after oil extraction, as a nutritional substrate supplement when growing the mushroom species Agaricus bisporus (Lange) Imbach and Pleurotus ostreatus (Jacq.) P. Kumm. Materials were applied at different doses at spawning. Along with non-supplemented substrates, commercial nutritional supplements were used as controls. Proximate analysis of mushrooms is also considered. For the cultivation of champignon, defatted pistachio meal has provided larger mushrooms (unitary weight and cap diameter) with firmer texture and greater content in dry weight and protein, without significant alterations in quantitative parameters. For Pleurotus ostreatus, the supplement led to significant yield increase, even providing up to 34.4% of increment compared to non-supplementation with meal, reaching a biological efficiency of 129.9 kg dt(-1) , when applied to the 15 g kg(-1) compost dose. Supplementation has also been conducted to increase dry weight, protein and fibre within carpophores and to decrease the energy value. Defatted pistachio meal has similar or better results compared to the commercial supplements used as reference. Compost supplementation with defatted pistachio meal in A. bisporus concerns mainly the quantitative parameters (size, texture, dry weight and protein). Based on the results obtained, this technique has greater potential of development for P. ostreatus commercial crops, basically due to expected increases in production, with a direct impact on benefits and crop profitability. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  16. Regional Assessment of Supplementation Project

    International Nuclear Information System (INIS)

    1991-10-01

    The Fish and Wildlife Program of the Northwest Power Planning Council (NPPC) prescribes several approaches to achieve its goal of doubling the salmon and steelhead runs of the Columbia River. Among those approaches are habitat restoration, improvements in adult and juvenile passage at dams and artificial propagation. Supplementation will be a major part of the new hatchery programs. The purpose of the Regional Assessment of Supplementation Project (RASP) is to provide an overview of ongoing and planned supplementation activities, to construct a conceptual framework and model for evaluating the potential benefits and risks of supplementation and to develop a plan for better regional coordination of research and monitoring and evaluation of supplementation. RASP has completed its first year of work. Progress toward meeting the first year's objectives and recommendations for future tasks are contained in this report

  17. Athletes and Supplements: Prevalence and Perspectives.

    Science.gov (United States)

    Garthe, Ina; Maughan, Ronald J

    2018-03-01

    In elite sport, where opponents are evenly matched, small factors can determine the outcome of sporting contests. Not all athletes know the value of making wise nutrition choices, but anything that might give a competitive edge, including dietary supplements, can seem attractive. Between 40% and 100% of athletes typically use supplements, depending on the type of sport, level of competition, and the definition of supplements. However, unless the athlete has a nutrient deficiency, supplementation may not improve performance and may have a detrimental effect on both performance and health. Dietary supplements are classified as a subcategory of food, so manufacturers are not required to provide evidence of product safety and efficacy, nor obtain approval from regulatory bodies before marketing supplements. This creates the potential for health risks, and serious adverse effects have been reported from the use of some dietary supplements. Athletes who compete in sports under an anti-doping code must also realize that supplement use exposes them to a risk of ingesting banned substances or precursors of prohibited substances. Government systems of regulations do not include specific laboratory testing for banned substances according to the WADA list, so a separate regulatory framework to evaluate supplements for their risk of provoking a failed doping test is needed. In the high-performance culture typical of elite sport, athletes may use supplements regardless of possible risks. A discussion around medical, physiological, cultural, and ethical questions may be warranted to ensure that the athlete has the information needed to make an informed choice.

  18. 40 CFR 60.2755 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... waste management plan? You must submit the waste management plan no later than the date specified in... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On...

  19. 30 CFR 250.468 - What well records am I required to submit?

    Science.gov (United States)

    2010-07-01

    ... OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations...) You must submit copies of logs or charts of electrical, radioactive, sonic, and other well-logging... drilling operations in the GOM OCS Region, you must submit form MMS-133, Well Activity Report, to the...

  20. 45 CFR 35.4 - Administrative claims; evidence and information to be submitted.

    Science.gov (United States)

    2010-10-01

    ... bearing on either the responsibility of the United States for the death or the damages claimed. (b... information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other competent...

  1. Vitamin C supplementation in pregnancy.

    Science.gov (United States)

    Rumbold, Alice; Ota, Erika; Nagata, Chie; Shahrook, Sadequa; Crowther, Caroline A

    2015-09-29

    Vitamin C supplementation may help reduce the risk of pregnancy complications such as pre-eclampsia, intrauterine growth restriction and maternal anaemia. There is a need to evaluate the efficacy and safety of vitamin C supplementation in pregnancy. To evaluate the effects of vitamin C supplementation, alone or in combination with other separate supplements on pregnancy outcomes, adverse events, side effects and use of health resources. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 March 2015) and reference lists of retrieved studies. All randomised or quasi-randomised controlled trials evaluating vitamin C supplementation in pregnant women. Interventions using a multivitamin supplement containing vitamin C or where the primary supplement was iron were excluded. Two review authors independently assessed trials for inclusion and risk of bias, extracted data and checked them for accuracy. Twenty-nine trials involving 24,300 women are included in this review. Overall, 11 trials were judged to be of low risk of bias, eight were high risk of bias and for 10 trials it was unclear. No clear differences were seen between women supplemented with vitamin C alone or in combination with other supplements compared with placebo or no control for the risk of stillbirth (risk ratio (RR) 1.15, 95% confidence intervals (CI) 0.89 to 1.49; 20,038 participants; 11 studies; I² = 0%; moderate quality evidence), neonatal death (RR 0.79, 95% CI 0.58 to 1.08; 19,575 participants; 11 studies; I² = 0%), perinatal death (average RR 1.07, 95% CI 0.77 to 1.49; 17,105 participants; seven studies; I² = 35%), birthweight (mean difference (MD) 26.88 g, 95% CI -18.81 to 72.58; 17,326 participants; 13 studies; I² = 69%), intrauterine growth restriction (RR 0.98, 95% CI 0.91 to 1.06; 20,361 participants; 12 studies; I² = 15%; high quality evidence), preterm birth (average RR 0.99, 95% CI 0.90 to 1.10; 22,250 participants; 16 studies; I² = 49%; high quality evidence

  2. Improvement the Yoghurt Nutritional Value, Organoleptic Properties and Preferences by Spirulina (Spirulina platensis) Supplementation

    Science.gov (United States)

    Suzery, M.; Hadiyanto; Sutanto, H.; Widiastuti, Y.; Judiono

    2018-04-01

    Spirulina sp has been identified as potential source food functional such as protein, amino acids and other high added value compounds from microalgae. One of the compounds is phycocyanin as also known for antioxidant use. This research was aimed to increase the nutritional value and organoleptic properties and preferences yoghurt by Spirulina platensis supplementation. Completely randomized controlled group design conducted by 31 respondents. Spirulina Research accomplished in Food Technology, Microbiology and Chemistry Laboratory at Bandung Health Polytechnic in Bandung. Samples divided randomly into three groups: (1) yoghurt standard supplemented 50 ml, (2) yoghurt and spirulina 1% supplemented 50 ml, (3) yoghurt and spirulina 1,2% supplemented 50 ml. Spirulina was added concentration by 0, 1, 1,2 % calculated by dx trial. Proximate analysis revealed the highest protein in enriched by spirulina 1%. However fat was lower 3.48 – 3.56 compare to control. All products found growing Lactobacillus acidophilus with a pH of 4.0 range. There was no microbial contamination such as E coli, Salmonella sp, Pseudomonas sp. Supplementation of spirulina to yoghurt products can be accepted by organoleptic, chemical and microbiological tests of concentrations of 1 and 1.2%. The material makes the blue colours more attractive and can be accepted by the expert panellist.

  3. Is there a place for nutritional supplements in the treatment of idiopathic male infertility?

    Directory of Open Access Journals (Sweden)

    Davide Arcaniolo

    2014-09-01

    Full Text Available Objective: Infertility affects 15% of couples in fertile age. Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT. The purpose of this study is to review the effects of nutritional supplements as medical treatment for idiopathic male infertility. Material and methods: A Pub Med and Medline review of the published studies utilizing nutritional supplements for the treatment of male infertility has been performed. Results: Clinical trials on Vitamin E, Vitamin A, Vitamin C. Arginine, Carnitine, N-Acetyl-Carnitine, Glutathione, Coenzyme Q10, Selenium and Zinc were reviewed. Although there is a wide variability in selected population, dose regimen and final outcomes, nutritional supplements both alone and in combination seems to be able to improve semen parameters (sperm count, sperm motility and morphology and pregnancy rate in infertile men. Conclusions: There are rising evidences from published randomized trials and systematic review suggesting that nutritional supplementation may improve semen parameters and the likelihood of pregnancy in men affected by OAT. This improvement, however, is not consistent and there is a wide variation in the treatment regimens used. Well designed and adequately powered RCTs are needed to better clarify the role of nutritional supplements as treatment for male infertility.

  4. Improvement the nutritional status of pre-school children following intervention with a supplement containing iron, zinc, copper, vitamin A, vitamin C and prebiotic

    Directory of Open Access Journals (Sweden)

    Luiza Carla Vidigal Castro

    Full Text Available Abstract This study investigated the effects of a vitamin and mineral fortified powder product supplemented with inulin, on the iron and vitamin A status of 110 pre-schools childrens in Viçosa, MG, Brazil. The 2 to 5-year-old children were submitted to anthropometric (weight and height, biochemical (erythrocytes, hemoglobin, mean corpuscular volume – MCV, mean corpuscular hemoglobin - MCH, serum iron, ferritin and serum retinol and dietary (direct food weighing, 24 h recall, and food intake record evaluations, at the beginning and at the end of a 45-day intervention. The supplement (30 g was provided daily as part of the afternoon snack, diluted in 100 mL of water, 5 times/week and it supplied 30% of the recommended daily doses of iron, zinc, copper and vitamins A and C. Dietary and biochemical data was compared by the Wilcoxon test, and anthropometric data by the paired t-test. Values of z-scores for weight and height, erythrocytes, hemoglobin, MCV, MCH and ferritin were significantly higher after intervention; no change was observed in serum retinol. The prebiotic-containing supplement significantly increased the intake of energy, macro and micronutrients, and was effective in improving the iron and anthropometric status.

  5. Programmatic environmental impact statement related to decontamination and disposal of radioactive wastes resulting from March 28, 1979 accident, Three Mile Island Nuclear Station, Unit 2 (Docket No. 50-320): Draft supplement dealing with post-defueling monitored storage and subsequent cleanup

    International Nuclear Information System (INIS)

    1988-04-01

    In accordance with the National Environmental Policy Act, the Commission's implementing regulations, and its April 27, 1981,Statement of Policy, the Programmatic environmental impact statement related to decontamination and disposal of radioactive wastes resulting from March 28, 1979 accident Three Mile Island Nuclear Station, Unit 2, NUREG-0683 (PEIS) is being supplemented. This draft supplement updates the enviromental evaluation of cleanup alternatives published in the PEIS, utilizing more complete and current information. Also, the draft supplement includes a specific environmental evaluation of the licensee's recently submitted proposal for post-defueling monitored storage. The NRC staff has concluded that the licensee's proposal to place the facility in a monitored storage configuration will not significantly affect the quality of the human environment. Further, any impacts from the long-term storage of the facility are outweighed by its benefits. 63 refs., 23 figs., 65 tabs

  6. 12 CFR 793.4 - Administrative claims; evidence and information to be submitted.

    Science.gov (United States)

    2010-01-01

    ... evidence or information which may have a bearing on the responsibility of the United States for the death... GOVERNMENT Procedures § 793.4 Administrative claims; evidence and information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or...

  7. Waste characterization emanated from kaolin submitted the improvement to process hydrocycloning; Caracterizacao do residuo provindo do beneficiamento do caulim submetido ao processo de hidrociclonagem

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa Neto, M.C.; Nunes, A.S.; Caetano, A.L.A.; Marques, V.C.; Macedo, D.A.; Ferreira, H.S.; Dutra, R.P.S., E-mail: netobarbosa.2@gmail.com [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Departamento de Engenharia de Materiais

    2016-07-01

    The hydrocyclones are equipment commonly used for separation of particles by size. The resulting material of this process usually presents different characteristics of the material, which was not subjected to treatment. Therefore, a study of the waste characteristics derived from kaolin processing submitted to hydrocycloning process compared to the same residue without going through the process was executed. The different samples were characterized by X-ray diffraction, X-ray fluorescence, particle size analysis and thermal analysis. The results indicate that the hydrocycloning not modify the mineralogical structure nor chemical material. The particle size analysis identified that the fine fraction, resulting from the process, presented particle size lower than the reference material. (author)

  8. Diferentes suplementos no cultivo in vitro de embriões de pinhão-manso Different supplements for in vitro embryo culture of physic nut

    Directory of Open Access Journals (Sweden)

    Claudinéia Ferreira Nunes

    2008-01-01

    Full Text Available O objetivo deste trabalho foi avaliar a influência do estádio de maturação dos frutos, no desenvolvimento de embriões de pinhão-manso (Jatropha curcas, cultivados em meio MS com diferentes suplementos: sacarose, água de coco e carvão ativado. Os frutos foram coletados, e os embriões de suas sementes extraídos assepticamente. Utilizaram-se duas condições experimentais: embriões oriundos de frutos em três estádios de desenvolvimento (imaturo, maduro e seco, colocados em meio de cultivo MS acrescido de sacarose (0, 15, 30 e 60 g L-1; embriões oriundos de frutos secos, colocados em meio MS acrescido de: 30 g L-1de sacarose, carvão ativado (0, 1, 2 e 3 g L-1 e de água de coco (0, 50, 100, 150, 200 e 250 mL L-1. O material foi mantido por 30 dias em sala de crescimento, sob condições ambientais controladas. Apenas os embriões zigóticos provenientes de frutos imaturos necessitam da suplementação de sacarose para sustentar sua germinação. O melhor desenvolvimento de embriões ocorre em meio MS suplementado com 60 g L-1 de sacarose. A associação de carvão ativado e água de coco proporcionam melhor crescimento de plântulas oriundas de embriões de sementes retiradas de frutos secos.The objective of this work was to evaluate the influence of maturation stages of physic nut fruits on the development of their embryos cultivated in MS medium supplemented with sucrose, coconut water and activated carbon. Fruits were collected, and their embryos were extracted aseptically. They were submitted to two experimental conditions: embryos from fruits in three development stages (immature, mature and dry were put into MS medium, supplemented with sucrose (0, 15, 30 and 60 g L-1; embryos derived from dry fruits were put into MS medium supplemented with sucrose 30 g L-1, activated carbon (0, 1, 2 and 3 g L-1, and coconut water (0, 50, 100, 150, 200 e 250 mL L-1. Explants were kept in a growth chamber under controlled conditions during 30

  9. Validation of an educative manual for patients with head and neck cancer submitted to radiation therapy

    Directory of Open Access Journals (Sweden)

    Flávia Oliveira de Almeida Marques da Cruz

    2016-01-01

    Full Text Available Abstract Objective: develop the content and face validation of an educative manual for patients with head and neck cancer submitted to radiation therapy. Method: descriptive methodological research. The Theory of Psychometrics was used for the validation process, developed by 15 experts in the theme area of the educative manual and by two language and publicity professionals. A minimum agreement level of 80% was considered to guarantee the validity of the material. Results: the items addressed in the assessment tool of the educative manual were divided in three blocks: objectives, structure and format, and relevance. Only one item, related to the sociocultural level of the target public, obtained an agreement rate <80%, and was reformulated based on the participants' suggestions. All other items were considered appropriate and/or complete appropriate in the three blocks proposed: objectives - 92.38%, structure and form - 89.74%, and relevance - 94.44%. Conclusion: the face and content validation of the educative manual proposed were attended to. This can contribute to the understanding of the therapeutic process the head and neck cancer patient is submitted to during the radiation therapy, besides supporting clinical practice through the nursing consultation.

  10. Bodybuilding supplementation and tooth decay.

    Science.gov (United States)

    Ali, M S; Batley, H; Ahmed, F

    2015-07-10

    Supplementation is a key component in bodybuilding and is increasingly being used by amateur weight lifters and enthusiasts to build their ideal bodies. Bodybuilding supplements are advertised to provide nutrients needed to help optimise muscle building but they can contain high amounts of sugar. Supplement users are consuming these products, while not being aware of their high sugar content, putting them at a higher risk of developing dental caries. It is important for dental professionals to recognise the increased risk for supplement users and to raise awareness, provide appropriate preventative advice and be knowledgeable of alternative products to help bodybuilders reach their goals, without increasing the risk of dental caries.

  11. Commercial cuts and carcass characteristics of sheep and goats supplemented with multinutritional blocks

    Directory of Open Access Journals (Sweden)

    Maiza Araújo C

    2017-09-01

    Full Text Available Objective. Aimed to identify the weight and yield of the commercial cuts, muscularity, and adiposity in the carcasses of sheep and goats grazing in the Caatinga supplemented with different sources of supplementations; these include feed-blocks. Material and methods. Sixty non-castrated males an initial average body weight of 18.63 ± 1.93 kg were used: 30 goats and 30 sheep all animals did not have a defined breed standard (WDBS. The experimental design used was entirely randomized (DIC, in factorial scheme 3x2 (three types of supplementation: mineral salt, MBs and MBs + buffel hay, and two species: sheep and goats and 10 replications. Animals were raised in a rangeland grazing system in an area with vegetation characteristic of Caatinga ecosystem under three types of supplementation: 1: only mineral salt; 2: Feed blocks (MBs; and 3: MBs + buffel hay There were measured the weight, yield and the components of left half-part of carcass of lambs and kids. Results. The sheep were superior to goats in carcass conformation, loin-eye area, index of muscularity of the leg and compactness index of the leg while the goats were superior to sheep in leg muscles weight. Conclusions. Sheep and Goats, when fed with supplementation of pasture feeding blocks in the Caatinga ecosystem; Supplementation with mineral salt and Multinutritional Blocks with and without Buffel can be used to improve herds in the caatinga, with similar results among the three. Sheep show more adiposity of meat than goats, in contrast, goats have higher musculature than sheep when fed with feed blocks.

  12. Screening of electrocatalytic materials for hydrogen evolution

    DEFF Research Database (Denmark)

    Björketun, Mårten; Bondarenko, Alexander S.; Abrams, Billie

    2010-01-01

    A general scheme for high-throughput screening of electrocatalysts is presented. By systematically exploiting a collection of theoretical and experimental materials databases, supplemented with quantum mechanical calculations, it locates systems that meet a set of pre-imposed selection criteria...

  13. Muscle Mass and Weight Gain Nutritional Supplements

    Science.gov (United States)

    Campbell, Bill

    There are numerous sports supplements available that claim to increase lean body mass. However, for these sports supplements to exert any favorable changes in lean body mass, they must influence those factors regulating skeletal muscle hypertrophy (i.e., satellite cell activity, gene transcription, protein translation). If a given sports supplement does favorably influence one of these regulatory factors, the result is a positive net protein balance (in which protein synthesis exceeds protein breakdown). Sports supplement categories aimed at eliciting a positive net protein balance include anabolic hormone enhancers, nutrient timing pre- and postexercise workout supplements, anticatabolic supplements, and nitric oxide boosters. Of all the sports supplements available, only a few have been subject to multiple clinical trials with repeated favorable outcomes relative to increasing lean body mass. This chapter focuses on these supplements and others that have a sound theoretical rationale in relation to increasing lean body mass.

  14. Inszenierung eines Supplements / Staging a Supplement

    Directory of Open Access Journals (Sweden)

    Thomas-M. Seibert

    2006-06-01

    Full Text Available Richter Adam, Anwalt Liebling und William, der Detektiv. Die Rechtspraxis setzt etwas voraus, das sie nicht nur begründet oder ergänzt, sondern grundsätzlich in Frage stellt. So macht der Zwang, in einem Verfahren zu entscheiden und zu begründen, zugleich deutlich, dass jede Form der Entscheidung unangemessen, unbegründet und in ganz anderer Weise neu herzustellen ist. Das ist das juridische Supplement im Geiste von Jacques Derrida. Supplementiert wird die Wahrheit des Rechts in anderen Medien: in Drama, Film und Literatur etwa. Dort wird in Szene gesetzt, was in der real erlebbaren Rechtswelt nicht wirklich erlebt werden kann, was aber doch – wie kein Amtsträger bestreiten würde – zum Verfahrensergebnis gehört. Judge Adam, Advocate “Liebling” and William, the Detective. Legal practice is based on something that is not only an integral part of it and complements it, but also puts it into question generally. The compulsion to argue and reach decisions in a legal trial clarifies simultaneously that all forms of decision are inapproprate, unreasonable, and can be recreated in an entirely new manner [to suit the needs of the trial]. This is the legalistic supplement in the spirit of Jacques Derrida. The legal truth is supplemented by other forms of media such as drama, film and literature, which are able to stage scenes that cannot be experienced in a real life legal world, but – as no legal official would deny – are an integral part of the trial and verdict procedure.

  15. Resposta hemática de tilápias-do-nilo alimentadas com dietas suplementadas com colina e submetidas a estímulo por baixa temperatura Hematic response of Nile tilapia fed diets supplemented with choline and submitted to stimulus by low temperature

    Directory of Open Access Journals (Sweden)

    Ademir Calvo Fernandes Junior

    2010-08-01

    Full Text Available Esta pesquisa foi realizada com o objetivo de avaliar a resposta hemática de tilápias-do-nilo (Oreochromis niloticus arraçoadas com dietas suplementadas com colina e submetidas a estímulo por baixa temperatura. O período experimental foi realizado em duas etapas: a primeira, de 109 dias, e a segunda, de 7 dias. Durante a primeira etapa, foram utilizados 192 alevinos com peso médio inicial de 4 g, distribuídos em 32 tanques-rede de 200 L instalados em aquários de mil litros. As rações foram formuladas de modo a apresentar 28,0% de proteína digestível e 3.100,0 kcal ED/kg e mesma concentração de aminoácidos. O delineamento experimental foi inteiramente casualizado com oito tratamentos e quatro repetições. As rações foram suplementadas com colina (cloreto de colina 60,0%, de modo a apresentar 100,0; 200,0; 400,0; 600,0; 800,0; 1.000,0 e 1.200,0 mg/kg de ração, e avaliadas em comparação a uma ração sem suplementação. Após o período de 109 dias, foram efetuadas as análises hematológicas dos peixes. Após as análises, os peixes foram transferidos para a sala de desafio e distribuídos em 24 aquários, onde foram mantidos a 17ºC durante sete dias. Após esse período, foram feitas as mesmas análises do período anterior ao desafio. A suplementação de colina não influenciou a eritropoiese ao estímulo pelo frio. A suplementa��ão dietética de colina não interfere na síntese de eritrócitos e leucócitos e a temperatura de 17,0ºC determina linfopenia e neutrofilia.The aim of this study was to evaluate the hematic response of Nile tilapia (Oreochromis niloticus fed diets supplemented with choline and submitted to temperature stress. The experimental period was realized in two phases: the first, during 109 days, and the second, for seven days. During the first stage, 192 fingerlings with average initial weight of 4 g were distributed in 32 net cages (200 L allocated in 1,000-L aquaria. The diets were formulated

  16. On some properties of ⊕-supplemented modules

    Directory of Open Access Journals (Sweden)

    A. Idelhadj

    2003-01-01

    Full Text Available A module M is ⊕-supplemented if every submodule of M has a supplement which is a direct summand of M. In this paper, we show that a quotient of a ⊕-supplemented module is not in general ⊕-supplemented. We prove that over a commutative ring R, every finitely generated ⊕-supplemented R-module M having dual Goldie dimension less than or equal to three is a direct sum of local modules. It is also shown that a ring R is semisimple if and only if the class of ⊕-supplemented R-modules coincides with the class of injective R-modules. The structure of ⊕-supplemented modules over a commutative principal ideal ring is completely determined.

  17. Performance of broiler chicken fed multicarbohydrases supplemented low energy diet

    Directory of Open Access Journals (Sweden)

    Kumar Govil

    2017-07-01

    Full Text Available Aim: Objective of this study was to investigate the effect of multicarbohydrases supplementation on performance of broilers fed low energy diet. Materials and Methods: A total of 75 days old chicks were selected and randomly divided into three treatments groups (T1, T2, and T3; each group contained 25 chicks distributed in five replicates of five chicks each. T1 group (positive control was offered control ration formulated as per Bureau of Indian Standards recommendations. In T2 group (negative control ration, metabolizable energy (ME was reduced by 100 kcal/kg diet. T3 group ration was same as that of T2 except that it was supplemented with multicarbohydrases (xylanase at 50 g/ton+mannanase at 50 g/ton+amylase at 40 g/ton. Feed intake and body weight of all experimental birds were recorded weekly. Metabolic trial was conducted for 3 days at the end of experiment to know the retention of nutrients. Results: Significant improvement (p<0.01 was observed in total weight gain, feed conversion efficiency, and performance index in broilers under supplementary group T3 as compared to T1 and T2 groups. Retention of crude protein and ether extract was significantly increased (p<0.05 in T3 group supplemented with multicarbohydrases as compared to other groups. Retention of dry matter, crude fiber, and nitrogen-free extract was comparable in all the three groups. Significantly highest dressed weight, eviscerated weight, and drawn weight (% of live body weight were observed in multicarbohydrases supplemented T3 group, however it was comparable in T1 and T2 groups. Conclusion: It was concluded that the supplementation of multicarbohydrases (xylanase at 50 g/ton+mannanase at 50 g/ton+amylase at 40 g/ton in low energy diet improved overall performance of broilers.

  18. Development of fire resistant, nontoxic aircraft interior materials

    Science.gov (United States)

    Haley, G.; Silverman, B.; Tajima, Y.

    1976-01-01

    All available newly developed nonmetallic polymers were examined for possible usage in developing fire resistant, nontoxic nonmetallic parts or assemblies for aircraft interiors. Specifically, feasibility for the development of clear films for new decorative laminates, compression moldings, injection molded parts, thermoformed plastic parts, and flexible foams were given primary considerations. Preliminary data on the flame resistant characteristics of the materials were obtained. Preliminary toxicity data were generated from samples of materials submitted from the contractor. Preliminary data on the physical characteristics of various thermoplastic materials to be considered for either compression molded, injection molded, or thermoformed parts were obtained.

  19. 75 FR 60404 - Information Collection Request Submitted to Office of Management and Budget

    Science.gov (United States)

    2010-09-30

    ... [OMB Control Number: 3002-0003] Information Collection Request Submitted to Office of Management and... United States will submit an Information Collection Request (ICR) to the Office of Management and Budget (OMB) requesting approval for the following collection of information: 3002-0003, Substitute...

  20. Prohibited Contaminants in Dietary Supplements.

    Science.gov (United States)

    Mathews, Neilson M

    With the increasing use of unregulated dietary supplements, athletes are at continued risk from adverse medical events and inadvertent doping. A review of Clinical Key, MEDLINE, and PubMed databases from 2012 to 2017 was performed using search terms, including dietary supplement, contamination, doping in athletes, inadvertent doping, and prohibited substances. The references of pertinent articles were reviewed for other relevant sources. Clinical review. Level 3. Poor manufacturing processes and intentional contamination with many banned substances continue to occur in dietary supplements sold in the United States. Certain sectors, such as weight loss and muscle-building supplements, pose a greater threat because they are more likely to be contaminated. Athletes will continue to be at risk for adverse events and failed doping tests due to contaminated dietary supplements until legislation changes how they are regulated. In the interim, there are several steps that can be taken to mitigate this risk, including improved education of medical staff and athletes and use of third party-certified products.

  1. DNA barcode identification of black cohosh herbal dietary supplements.

    Science.gov (United States)

    Baker, David A; Stevenson, Dennis W; Little, Damon P

    2012-01-01

    Black cohosh (Actaea racemosa) herbal dietary supplements are commonly consumed to treat menopausal symptoms, but there are reports of adverse events and toxicities associated with their use. Accidental misidentification and/or deliberate adulteration results in harvesting other related species that are then marketed as black cohosh. Some of these species are known to be toxic to humans. We have identified two matK nucleotides that consistently distinguish black cohosh from related species. Using these nucleotides, an assay was able to correctly identify all of the black cohosh samples in the validation set. None of the other Actaea species in the validation set were falsely identified as black cohosh. Of 36 dietary supplements sequenced, 27 (75%) had a sequence that exactly matched black cohosh. The remaining nine samples (25%) had a sequence identical to that of three Asian Actaea species (A. cimicifuga, A. dahurica, and A. simplex). Manufacturers should routinely test plant material using a reliable assay to ensure accurate labeling.

  2. 40 CFR 141.809 - Supplemental treatment.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Supplemental treatment. 141.809... treatment. (a) Any supplemental drinking water treatment units installed onboard existing or new aircraft... the manufacturer's plans and specifications and FAA requirements. (b) Water supplemental treatment and...

  3. Use of dietary supplements among Brazilian athletes

    Directory of Open Access Journals (Sweden)

    Hellen Clair Garcez NABUCO

    Full Text Available ABSTRACT Objective: To investigate the prevalence and establish the profile of the consumption of dietary supplements among Brazilian athletes. Methods: A total of 182 athletes of both genders from 20 different sports participated in this study. The athletes answered a questionnaire containing sociodemographic and sports-related questions and were interviewed about the consumption of dietary supplements. Results: Forty seven percent of athletes reported having consumed at least one type of dietary supplement and 38% said they use more than three different types of supplements concurrently. Whey protein was the most commonly consumed supplement, and the most frequently mentioned reason for its consumption was performance improvement. The main source of information was coaches, and individual sport athletes were the greatest consumers and the most likely to seek dietary supplement. Conclusion: Approximately half of the participants used dietary supplements, which on most occasions were recommended by coaches. The consumption profile also revealed multiple supplementation practice and showed that nutrition education is essential for this specific population.

  4. Adverse Effects of Nutraceuticals and Dietary Supplements.

    Science.gov (United States)

    Ronis, Martin J J; Pedersen, Kim B; Watt, James

    2018-01-06

    Over 70% of Americans take some form of dietary supplement every day, and the supplement industry is currently big business, with a gross of over $28 billion. However, unlike either foods or drugs, supplements do not need to be registered or approved by the US Food and Drug Administration (FDA) prior to production or sales. Under the Dietary Supplement Health and Education Act of 1994, the FDA is restricted to adverse report monitoring postmarketing. Despite widespread consumption, there is limited evidence of health benefits related to nutraceutical or supplement use in well-nourished adults. In contrast, a small number of these products have the potential to produce significant toxicity. In addition, patients often do not disclose supplement use to their physicians. Therefore, the risk of adverse drug-supplement interactions is significant. An overview of the major supplement and nutraceutical classes is presented here, together with known toxic effects and the potential for drug interactions.

  5. Development and use of reference materials and quality control materials

    International Nuclear Information System (INIS)

    2003-04-01

    Current knowledge is summarized on correct use of commercially available certified reference materials (CRMs) and reference materials (RMs). Acknowledged are also the limitations and restrictions analysts have to face if they want to apply quality control. The concept of in-house RMs or quality control materials (QCMs) is advocated to supplement the use of CRMs for quality control purposes. On hand advice on how to select, prepare, characterize and use these QCMs is given from the experts' perspective. Several scenarios are described to make this concept widely applicable to: advanced laboratories with CRMs with validated analytical techniques available, laboratories with less experience and facilities, as well as cases were labile compounds and unstable matrices are involved. Each scenario considers different approaches to overcome the lack of appropriate CRMs and advise on the preparation of QCMs, which might fit the particular purpose

  6. Development and use of reference materials and quality control materials

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-04-01

    Current knowledge is summarized on correct use of commercially available certified reference materials (CRMs) and reference materials (RMs). Acknowledged are also the limitations and restrictions analysts have to face if they want to apply quality control. The concept of in-house RMs or quality control materials (QCMs) is advocated to supplement the use of CRMs for quality control purposes. On hand advice on how to select, prepare, characterize and use these QCMs is given from the experts' perspective. Several scenarios are described to make this concept widely applicable to: advanced laboratories with CRMs with validated analytical techniques available, laboratories with less experience and facilities, as well as cases were labile compounds and unstable matrices are involved. Each scenario considers different approaches to overcome the lack of appropriate CRMs and advise on the preparation of QCMs, which might fit the particular purpose.

  7. Dietary red palm oil supplementation reduces myocardial infarct size in an isolated perfused rat heart model

    Directory of Open Access Journals (Sweden)

    Esterhuyse Adriaan J

    2010-06-01

    Full Text Available Abstract Background and Aims Recent studies have shown that dietary red palm oil (RPO supplementation improves functional recovery following ischaemia/reperfusion in isolated hearts. The main aim of this study was to investigate the effects of dietary RPO supplementation on myocardial infarct size after ischaemia/reperfusion injury. The effects of dietary RPO supplementation on matrix metalloproteinase-2 (MMP2 activation and PKB/Akt phosphorylation were also investigated. Materials and methods Male Wistar rats were divided into three groups and fed a standard rat chow diet (SRC, a SRC supplemented with RPO, or a SRC supplemented with sunflower oil (SFO, for a five week period, respectively. After the feeding period, hearts were excised and perfused on a Langendorff perfusion apparatus. Hearts were subjected to thirty minutes of normothermic global ischaemia and two hours of reperfusion. Infarct size was determined by triphenyltetrazolium chloride staining. Coronary effluent was collected for the first ten minutes of reperfusion in order to measure MMP2 activity by gelatin zymography. Results Dietary RPO-supplementation decreased myocardial infarct size significantly when compared to the SRC-group and the SFO-supplemented group (9.1 ± 1.0% versus 30.2 ± 3.9% and 27.1 ± 2.4% respectively. Both dietary RPO- and SFO-supplementation were able to decrease MMP2 activity when compared to the SRC fed group. PKB/Akt phosphorylation (Thr 308 was found to be significantly higher in the dietary RPO supplemented group when compared to the SFO supplemented group at 10 minutes into reperfusion. There was, however, no significant changes observed in ERK phosphorylation. Conclusions Dietary RPO-supplementation was found to be more effective than SFO-supplementation in reducing myocardial infarct size after ischaemia/reperfusion injury. Both dietary RPO and SFO were able to reduce MMP2 activity, which suggests that MMP2 activity does not play a major role in

  8. Influence of finishing/polishing on color stability and surface roughness of composites submitted to accelerated artificial aging

    Directory of Open Access Journals (Sweden)

    Gustavo Da Col dos Santos Pinto

    2013-01-01

    Full Text Available Aim: To assess the influence of finishing/polishing procedure on color stability (ΔE and surface roughness (Ra of composites (Heliomolar and Tetric - color A2 submitted to accelerated artificial aging (AAA. Materials and Methods : Sixty test specimens were made of each composite (12 mm × 2 mm and separated into six groups (n = 10, according to the type of finishing/polishing to which they were submitted: C, control; F, tip 3195 F; FF, tip 3195 FF; FP, tip 3195 F + diamond paste; FFP, tip 3195 FF + diamond paste; SF, Sof-Lex discs. After polishing, controlled by an electromechanical system, initial color (spectrophotometer PCB 6807 BYK GARDNER and Ra (roughness meter Surfcorder SE 1700, cut-off 0.25 mm readings were taken. Next, the test specimens were submitted to the AAA procedure (C-UV Comexim for 384 hours, and at the end of this period, new color readings and R a were taken. Results: Statistical analysis [2-way analysis of variance (ANOVA, Bonferroni, P < 0.05] showed that all composites demonstrated ΔE alteration above the clinically acceptable limits, with the exception of Heliomolar composite in FP. The greatest ΔE alteration occurred for Tetric composite in SF (13.38 ± 2.10 statistically different from F and FF (P < 0.05. For Ra , Group F showed rougher samples than FF with statistically significant difference (P < 0.05. Conclusion: In spite of the surface differences, the different finishing/polishing procedures were not capable of providing color stability within the clinically acceptable limits.

  9. The Use Potential of Traditional Building Materials for the Realization of Structures by Modern Methods of Construction

    Directory of Open Access Journals (Sweden)

    Spišáková Marcela

    2015-11-01

    Full Text Available The sustainable building has taken off in recent years with many investors looking for new and different methods of construction. The traditional building materials can be made out of natural materials, while others can help to lower energy costs of the occupant once built. Regardless of what the goal of the investor is, traditional building materials and their use is on the rise. The submitted paper provides an overview of natural building materials and possible modern building systems using these construction materials. Based on the questionnaire survey is defined the use potential of traditional building materials for the realization of the construction by methods of modern constructions and then are determined the drivers and barriers of traditional materials through using modern methods of construction. Considering the analysis of the achieved results, we can identify the gaps in the construction market in Slovakia and also to assess the perception of potential investors in the field of traditional building materials use, which is the purpose of submitted paper.

  10. Functional food supplements to ameliorate the secondary complications in high fructose fed diabetic rats.

    Science.gov (United States)

    Gite, S S; Yadav, S A; Nilegaonkar, S S; Agte, V V

    2017-05-24

    Functional foods are the most natural and safest source of health ingredients, providing health benefits beyond basic nutrition, and hence can be used as supplements for the prevention of secondary complications in diabetes. Persistent diabetes may cause glycation of various tissue proteins such as of those in lens, kidney, blood, and brain, which may further lead to the development of pathological conditions such as cataract and cardiovascular diseases. This study on adult rats was designed to assess if the functional food supplements A and B (proprietary blends of antioxidant rich plant materials) can reduce secondary complications such as cataract, dyslipidemia, and oxidative stress under severe diabetic conditions. After nine weeks of intervention of the supplements, it was found that the % HbA1c levels in the formulation group B significantly (p functional foods in the effective management of secondary complications associated with severe diabetic conditions.

  11. Cardiovascular Effects of Calcium Supplements

    Directory of Open Access Journals (Sweden)

    Ian R. Reid

    2013-07-01

    Full Text Available Calcium supplements reduce bone turnover and slow the rate of bone loss. However, few studies have demonstrated reduced fracture incidence with calcium supplements, and meta-analyses show only a 10% decrease in fractures, which is of borderline statistical and clinical significance. Trials in normal older women and in patients with renal impairment suggest that calcium supplements increase the risk of cardiovascular disease. To further assess their safety, we recently conducted a meta-analysis of trials of calcium supplements, and found a 27%–31% increase in risk of myocardial infarction, and a 12%–20% increase in risk of stroke. These findings are robust because they are based on pre-specified analyses of randomized, placebo-controlled trials and are consistent across the trials. Co-administration of vitamin D with calcium does not lessen these adverse effects. The increased cardiovascular risk with calcium supplements is consistent with epidemiological data relating higher circulating calcium concentrations to cardiovascular disease in normal populations. There are several possible pathophysiological mechanisms for these effects, including effects on vascular calcification, vascular cells, blood coagulation and calcium-sensing receptors. Thus, the non-skeletal risks of calcium supplements appear to outweigh any skeletal benefits, and are they appear to be unnecessary for the efficacy of other osteoporosis treatments.

  12. 76 FR 75894 - Information Collection Activities: Pipelines and Pipeline Rights-of-Way; Submitted for Office of...

    Science.gov (United States)

    2011-12-05

    ...) Submit repair report 3 1008(f) Submit report of pipeline failure analysis...... 30 1008(g) Submit plan of... usual and customary business practice; required burden is minimal to make available to BSEE. Estimated... and provide your total capital and startup cost components or annual operation, maintenance, and...

  13. The Environmental Assessment and Management (TEAM) Guide: New York Supplement

    Science.gov (United States)

    2010-03-01

    including letter enamels , poster colors, copy blockers, and bulletin enamels (6 NYCRR 205.2) [Added March 2006]. • Heat Input - the heat released...formulated to cover holes and minor cracks and conceal surface irregularities, which is applied in a single coat of at least 10 mils (0.010 inch) dry film...books, magazines, catalogs, brochures, directors, newspaper supplements and other types of printed materials (6 NYCRR 234.1). • Quick-Dry Enamel

  14. 42 CFR 422.102 - Supplemental benefits.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Supplemental benefits. 422.102 Section 422.102... (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Benefits and Beneficiary Protections § 422.102 Supplemental benefits. (a) Mandatory supplemental benefits. (1) Subject to CMS approval, an MA organization may...

  15. 20 CFR 227.2 - Initial supplemental annuity rate.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Initial supplemental annuity rate. 227.2... COMPUTING SUPPLEMENTAL ANNUITIES § 227.2 Initial supplemental annuity rate. The supplemental annuity rate... supplemental annuity rate is $43 for an employee with 30 or more years of service. ...

  16. Dietary supplements and team-sport performance.

    Science.gov (United States)

    Bishop, David

    2010-12-01

    A well designed diet is the foundation upon which optimal training and performance can be developed. However, as long as competitive sports have existed, athletes have attempted to improve their performance by ingesting a variety of substances. This practice has given rise to a multi-billion-dollar industry that aggressively markets its products as performance enhancing, often without objective, scientific evidence to support such claims. While a number of excellent reviews have evaluated the performance-enhancing effects of most dietary supplements, less attention has been paid to the performance-enhancing claims of dietary supplements in the context of team-sport performance. Dietary supplements that enhance some types of athletic performance may not necessarily enhance team-sport performance (and vice versa). Thus, the first aim of this review is to critically evaluate the ergogenic value of the most common dietary supplements used by team-sport athletes. The term dietary supplements will be used in this review and is defined as any product taken by the mouth, in addition to common foods, that has been proposed to have a performance-enhancing effect; this review will only discuss substances that are not currently banned by the World Anti-Doping Agency. Evidence is emerging to support the performance-enhancing claims of some, but not all, dietary supplements that have been proposed to improve team-sport-related performance. For example, there is good evidence that caffeine can improve single-sprint performance, while caffeine, creatine and sodium bicarbonate ingestion have all been demonstrated to improve multiple-sprint performance. The evidence is not so strong for the performance-enhancing benefits of β-alanine or colostrum. Current evidence does not support the ingestion of ribose, branched-chain amino acids or β-hydroxy-β-methylbutyrate, especially in well trained athletes. More research on the performance-enhancing effects of the dietary supplements

  17. 24 CFR 3282.354 - Submittal of false information or refusal to submit information.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Submittal of false information or... ENFORCEMENT REGULATIONS Primary Inspection Agencies § 3282.354 Submittal of false information or refusal to submit information. The submittal of false information or the refusal to submit information required...

  18. 27 CFR 73.34 - When is an electronically submitted form considered timely filed?

    Science.gov (United States)

    2010-04-01

    ... AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.34 When is an electronically submitted form considered timely filed? If you submit a form to our electronic...

  19. EXPERIENCE OF USING THE “DE ALEX” DIETARY SUPPLEMENT: RESULTS OF A SINGLE CENTER STUDY

    Directory of Open Access Journals (Sweden)

    A. O. Vasil’ev

    2017-01-01

    Full Text Available Introduction. Since their first appearance and through present day, dietary supplements remain popular among customers. In medical practice, dietary supplements are used as an additional source of nutrients and biologically active compounds aimed at optimization of various types of metabolism as well as normalization and/or improvement of functional state of organs and systems.Objective: is to evaluate effectiveness and safety of a dietary supplement “De Alex” in patients with benign prostatic hyperplasia (BPH.Materials and methods. The study included 35 volunteers who signed the informed consent form and received treatment at urology departments of the S.I. Spasokukotsky Municipal Clinical Hospital. The main group included 20 men, the control group included 15 men. “De Alex” dietary supplement was administered according to the following scheme: 1 tablet 3 times a day for the first 3 months, then 4 tablets a day for 2 more months. Clinical, laboratory and instrumental data were evaluated as well as validated questionnaires filled out by the patients.Results. There weren’t any allergic reactions or individual intolerance to the “De Alex”  dietary supplement in the main group. The total IPSS score decreased in all patients, and symptoms of the lower urinary tract were less pronounced. “De Alex” administration didn’t affect the levels of prostate-specific antigen and testosterone. In the studied subgroups, a moderate decrease of the prostate volume was observed. Conclusions. The “De Alex” dietary supplement has a satisfactory safety profile. In patients with BPH the supplement causes a moderate decrease of the prostate volume.

  20. Effect of brewer’s yeast supplementation on serum glucose and lipids in type II diabetic patients with dislipidemia

    OpenAIRE

    Sh. Ravanshad; H. Khosvani Borujeni; M. Soveid; B. Zeighami

    2005-01-01

    Background and purpose : Chromium deficiency leads to impaired glucose and lipid metabolism. Chromium supplementation in type II diabetic patients improves glucose and lipid profiles. Organic chromium, such as found in brewer’s yeast, is much better absorbed than inorganic chromium. In this study, the effect of chromium supplementation in the form of brewer’s yeast on glucose and lipid profile of diabetic patients were evaluated.Materials and methods : In a clinical trial study (before and af...

  1. Renal excretion of water in men under hypokinesia and physical exercise with fluid and salt supplementation

    Science.gov (United States)

    Zorbas, Yan G.; Federenko, Youri F.; Togawa, Mitsui N.

    It has been suggested that under hypokinesia (reduced number of steps/day) and intensive physical exercise, the intensification of fluid excretion in men is apparently caused as a result of the inability of the body to retain optimum amounts of water. Thus, to evaluate this hypothesis, studies were performed with the use of fluid and sodium chloride (NaCl) supplements on 12 highly trained physically healthy male volunteers aged 19-24 years under 364 days of hypokinesis (HK) and a set of intensive physical exercises (PE). They were divided into two groups with 6 volunteers per group. The first group of subjects were submitted to HK and took daily fluid and salt supplements in very small doses and the second group of volunteers were subjected to intensive PE and fluid-salt supplements. For the simulation of the hypokinetic effect, both groups of subjects were kept under an average of 4000 steps/day. During the prehypokinetic period of 60 days and under the hypokinetic period of 364 days water consumed and eliminated in urine by the men, water content in blood, plasma volume, rate of glomerular filtration, renal blood flow, osmotic concentration of urine and blood were measured. Under HK, the rate of renal excretion of water increased considerably in both groups. The additional fluid and salt intake failed to normalize water balance adequately under HK and PE. It was concluded that negative water balance evidently resulted not from shortage of water in the diet but from the inability of the body to retain optimum amounts of fluid under HK and a set of intensive PEs.

  2. 7 CFR 28.954 - Costs of submitting samples.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Costs of submitting samples. 28.954 Section 28.954 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER...

  3. 43 CFR 7.32 - Supplemental definitions.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Supplemental definitions. 7.32 Section 7... RESOURCES Department of the Interior Supplemental Regulations § 7.32 Supplemental definitions. For purposes of this subpart, the following definitions will be used: (a) Site of religious or cultural importance...

  4. 22 CFR 71.12 - Dietary supplements.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Dietary supplements. 71.12 Section 71.12... Incarcerated Abroad § 71.12 Dietary supplements. (a) Eligibility criteria. A prisoner is considered eligible for the dietary supplement program under the following general criteria: (1) An evaluation by a...

  5. Progesterone supplementation after ovulation: effects on corpus luteum function and on fertility of dairy cows subjected to AI or ET.

    Science.gov (United States)

    Monteiro, Pedro L J; Nascimento, Anibal B; Pontes, Guilherme C S; Fernandes, Gabriela O; Melo, Leonardo F; Wiltbank, Milo C; Sartori, Roberto

    2015-10-15

    .7% vs. 21.3% vs. 15.2%, for ET-Control, ET-CIDR-4, and ET-CIDR-14, respectively), with no effect on pregnancy loss. Therefore, although CIDR insertion on Day 3 after FTAI did not affect CL function and increased circulating P4, it did not increase pregnancy per AI in lactating dairy cows submitted to FTAI. Moreover, P4 supplementation decreased pregnancy per ET in lactating recipient cows. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. NASA Microgravity Materials Science Conference

    Science.gov (United States)

    Gillies, D. C. (Compiler); McCauley, D. E. (Compiler)

    1999-01-01

    The Microgravity Materials Science Conference was held July 14-16, 1998 at the Von Braun Center in Huntsville, AL. It was organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Microgravity Research Division at NASA Headquarters, and hosted by the NASA Marshall Space Flight Center and the Alliance for Microgravity Materials Science and Applications. It was the third NASA conference of this type in the microgravity materials science discipline. The microgravity science program sponsored approximately 125 investigations and 100 principal investigators in FY98, almost all of whom made oral or poster presentations at this conference. The conference's purpose was to inform the materials science community of research opportunities in reduced gravity in preparation for a NASA Research Announcement scheduled for release in late 1998 by the Microgravity Research Division at NASA Headquarters. The conference was aimed at materials science researchers from academia, industry, and government. A tour of the Marshall Space Flight Center microgravity research facilities was held on July 16, 1998. This volume is comprised of the research reports submitted by the principal investigators after the conference.

  7. High capacity anode materials for lithium ion batteries

    Science.gov (United States)

    Lopez, Herman A.; Anguchamy, Yogesh Kumar; Deng, Haixia; Han, Yongbon; Masarapu, Charan; Venkatachalam, Subramanian; Kumar, Suject

    2015-11-19

    High capacity silicon based anode active materials are described for lithium ion batteries. These materials are shown to be effective in combination with high capacity lithium rich cathode active materials. Supplemental lithium is shown to improve the cycling performance and reduce irreversible capacity loss for at least certain silicon based active materials. In particular silicon based active materials can be formed in composites with electrically conductive coatings, such as pyrolytic carbon coatings or metal coatings, and composites can also be formed with other electrically conductive carbon components, such as carbon nanofibers and carbon nanoparticles. Additional alloys with silicon are explored.

  8. Amino acid derivative-mediated detoxification and functionalization of dual cure dental restorative material for dental pulp cell mineralization.

    Science.gov (United States)

    Minamikawa, Hajime; Yamada, Masahiro; Iwasa, Fuminori; Ueno, Takeshi; Deyama, Yoshiaki; Suzuki, Kuniaki; Yawaka, Yasutaka; Ogawa, Takahiro

    2010-10-01

    Current dental restorative materials are only used to fill the defect of hard tissues, such as dentin and enamel, because of their cytotoxicity. Therefore, exposed dental pulp tissues in deep cavities must be first covered by a pulp capping material like calcium hydroxide to form a layer of mineralized tissue. However, this tissue mineralization is based on pathological reaction and triggers long-lasting inflammation, often causing clinical problems. This study tested the ability of N-acetyl cysteine (NAC), amino acid derivative, to reduce cytotoxicity and induce mineralized tissue conductivity in resin-modified glass ionomer (RMGI), a widely used dental restorative material having dual cure mechanism. Rat dental pulp cells were cultured on untreated or NAC-supplemented RMGI. NAC supplementation substantially increased the percentage of viable cells from 46.7 to 73.3% after 24-h incubation. Cell attachment, spreading, proliferative activity, and odontoblast-related gene and protein expressions increased significantly on NAC-supplemented RMGI. The mineralization capability of cells, which was nearly suppressed on untreated RMGI, was induced on NAC-supplemented RMGI. These improved behaviors and functions of dental pulp cells on NAC-supplemented RMGI were associated with a considerable reduction in the production of intracellular reactive oxygen species and with the increased level of intracellular glutathione reserves. These results demonstrated that NAC could detoxify and functionalize RMGIs via two different mechanisms involving in situ material detoxification and antioxidant cell protection. We believe that this study provides a new approach for developing dental restorative materials that enables mineralized tissue regeneration.

  9. Mineral supplementation for grazing ruminants

    International Nuclear Information System (INIS)

    McDowell, L.R.; Conrad, J.H.; Ellis, G.L.

    1986-01-01

    Grazing ruminants to which concentrate feeds cannot be economically fed must rely on self-feeding of mineral supplements. A number of factors affect mineral consumption of free-choice mixtures. Livestock exhibit little nutritional wisdom and will select palatable mixtures in preference to mixtures designed to meet their requirements. Palatability and appetite stimulators are often used to achieve a more uniform herd-wide consumption. It is best to formulate free-choice mixtures on the basis of analyses or other available data. However, when no information on mineral status is known, a free-choice complete mineral supplement is warranted. A 'complete' mineral mixture usually includes salt, a low fluoride P source, Ca, Co, Cu, I, Mn and Zn. Selenium, Mg, K, S, Fe or additional elements can be incorporated into a mineral supplement as new information suggests a need. The detriment to ruminant production caused by providing Ca, Se and Cu in excess can be greater than any benefit derived by providing a mineral supplement. In regions where high forage Mo predominates, three to five times the Cu content in mineral mixtures is needed to counteract Mo toxicity. Supplemental minerals are most critical during the wet season, when cattle are gaining weight rapidly and energy and protein supplies are adequate. Economic return on mineral supplementation is high. (author)

  10. 20 CFR 226.16 - Supplemental annuity.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Supplemental annuity. 226.16 Section 226.16... EMPLOYEE, SPOUSE, AND DIVORCED SPOUSE ANNUITIES Computing an Employee Annuity § 226.16 Supplemental annuity. A supplemental annuity is payable in addition to tiers I and II and the vested dual benefit to an...

  11. Oral potassium supplementation in surgical patients.

    Science.gov (United States)

    Hainsworth, Alison J; Gatenby, Piers A

    2008-08-01

    Hospital inpatients are frequently hypokalaemic. Low plasma potassium levels may cause life threatening complications, such as cardiac arrhythmias. Potassium supplementation may be administered parenterally or enterally. Oral potassium supplements have been associated with oesophageal ulceration, strictures and gastritis. An alternative to potassium salt tablets or solution is dietary modification with potassium rich food stuffs, which has been proven to be a safe and effective method for potassium supplementation. The potassium content of one medium banana is equivalent to a 12 mmol potassium salt tablet. Potassium supplementation by dietary modification has been shown to be equally efficacious to oral potassium salt supplementation and is preferred by the majority of patients. Subsequently, it is our practice to replace potassium using dietary modification, particularly in surgical patients having undergone oesophagogastrectomy or in those with peptic ulcer disease.

  12. Commercially marketed supplements for bodybuilding athletes.

    Science.gov (United States)

    Grunewald, K K; Bailey, R S

    1993-02-01

    We conducted a survey of 624 commercially available supplements targeted towards bodybuilding athletes. Over 800 performance claims were made for these supplements. Supplements include amino acids, boron, carnitine, choline, chromium, dibencozide, ferulic acid, gamma oryzanol, medium chain triglycerides, weight gain powders, Smilax compounds and yohimbine. Many performance claims advertised were not supported by published research studies. In some instances, we found no research to validate the claims; in other cases, research findings were extrapolated to inappropriate applications. For example, biological functions of some non-essential compounds were interpreted as performance claims for the supplements. Claims for others were based on their ability to enhance hormonal release or activity. We suggest that more research be conducted on this group of athletes and their nutritional needs. Furthermore, the effectiveness and safety of supplements merit further investigation.

  13. Creatine supplementation and swim performance: a brief review.

    Science.gov (United States)

    Hopwood, Melissa J; Graham, Kenneth; Rooney, Kieron B

    2006-03-01

    Nutritional supplements are popular among athletes participating in a wide variety of sports. Creatine is one of the most commonly used dietary supplements, as it has been shown to be beneficial in improving performance during repeated bouts of high-intensity anaerobic activity. This review examines the specific effects of creatine supplementation on swimming performance, and considers the effects of creatine supplementation on various measures of power development in this population. Research performed on the effect of creatine supplementation on swimming performance indicates that whilst creatine supplementation is ineffective in improving performance during a single sprint swim, dietary creatine supplementation may benefit repeated interval swim set performance. Considering the relationship between sprint swimming performance and measurements of power, the effect of creatine supplementation on power development in swimmers has also been examined. When measured on a swim bench ergometer, power development does show some improvement following a creatine supplementation regime. How this improvement in power output transfers to performance in the pool is uncertain. Although some evidence exists to suggest a gender effect on the performance improvements seen in swimmers following creatine supplementation, the majority of research indicates that male and female swimmers respond equally to supplementation. A major limitation to previous research is the lack of consideration given to the possible stroke dependant effect of creatine supplementation on swimming performance. The majority of the research conducted to date has involved examination of the freestyle swimming stroke only. The potential for performance improvements in the breaststroke and butterfly swimming strokes is discussed, with regards to the biomechanical differences and differences in efficiency between these strokes and freestyle. Key PointsCreatine supplementation does not improve single sprint

  14. Should You Take Dietary Supplements?

    Science.gov (United States)

    ... 2013 Print this issue Should You Take Dietary Supplements? A Look at Vitamins, Minerals, Botanicals and More ... Gut in Check Wise Choices Safe Use of Supplements Tell all of your health care providers about ...

  15. 49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Refusal to submit to a drug or alcohol test. 655... TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PREVENTION OF ALCOHOL MISUSE AND PROHIBITED DRUG USE IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each...

  16. Fat supplementation ("Flushing" on the postpartum beef cows submitted to early weaning: performance Suplementação com gordura ("Flushing" para vacas de corte no pós-parto submetidas ao desmame precoce: desempenho animal

    Directory of Open Access Journals (Sweden)

    José Luiz Moletta

    2008-06-01

    Full Text Available The effects of short-time fat supplementation flushing on animal performance (final body weight and average daily gain of postpartum beef cows, submitted to the early weaning were evaluatrd. Two hundred and fifty eight beef cows from the following genetic groups were used: Aberdeen Angus (n = 21, Aberdeen Angus x Canchim (n = 20, Canchim x Aberdeen Angus (n = 52, Charoles x Caracu (n = 29, Charolês (n = 18, Cachim (n = 34, Caracu (n = 35, Caracu x Charoles (n = 26 and Purunã (n = 23, with 418.1±14.0 kg of body weight and pregnant. These animals were split into two treatments: flushing (30% soybean grain + 70% corn ground grain and without supplementation. There was no flushing effect on final body weight (436.6 kg and average daily gain (0.83 kg. November period, cows had higher final body weight (441.6 kg and average daily gain (1.01 kg. There was no effect of flushing on variables.O objetivou-se, neste experimento, avaliar o efeito da suplementação de gordura por um curto período de tempo (flushing sobre o desempenho animal (peso vivo final e ganho médio diário de fêmeas de corte no pós-parto, submetidas ao desmame precoce. Foram utilizadas 258 vacas, dos grupos genéticos: Aberdeen Angus (n = 21, Aberdeen Angus x Canchim (n = 20, Canchim x Aberdeen Angus (n = 52, Charolês x Caracu (n = 29, Charolês (n = 18, Cachim (n = 34, Caracu (n = 35, Caracu x Charolês (n = 26 e Purunã (n = 23, com peso vivo médio de 418,1±14,0 kg e diagnóstico de prenhez positivo. Os animais foram distribuídos nos tratamentos flushing (30% de grão de soja + 70% de milho grão moído e não suplementados. Foram avaliados três períodos de acordo com a ordem de parição: setembro, outubro e novembro. Não houve efeito do flushing sobre o peso vivo final (436,6 kg e ganho médio diário (0,83 kg. O período de novembro apresentou maior peso vivo final (441,6 kg e ganho médio diário (1,01 kg. O fornecimento de gordura (flushing para fêmeas de corte no

  17. Dietary Supplements: What You Need to Know

    Science.gov (United States)

    ... Food Home Food Resources for You Consumers Dietary Supplements: What You Need to Know Share Tweet Linkedin ... and nutrients you personally need. What are dietary supplements? Dietary supplements include such ingredients as vitamins, minerals, ...

  18. 77 FR 70486 - Supplemental Environmental Impact Statement for Proposed Dewey-Burdock In-Situ Uranium Recovery...

    Science.gov (United States)

    2012-11-26

    ... Proposed Dewey- Burdock In-Situ Uranium Recovery Project in Custer and Fall River Counties, SD AGENCY... draft Supplemental Environmental Impact Statement (Draft SEIS) for the Dewey-Burdock In-Situ Uranium... NRC for a new source materials license for the Dewey-Burdock ISR Project. Powertech is proposing to...

  19. Supplemental Colleges

    Data.gov (United States)

    Department of Homeland Security — The Supplemental Colleges layer attempts to capture additional Post Secondary Education campuses of colleges and universities associated with a single campus listed...

  20. Effect of ionizing radiation on the taste function of patients submitted to head and neck radiotherapy

    International Nuclear Information System (INIS)

    Silva, Amaro Ilidio Vespasiano; Galante, Celio

    2011-01-01

    Objective: to evaluate the effects of ionizing radiation on the taste function in patients submitted to radiotherapy in the head and neck region. Materials and methods: twenty patients diagnosed with head and neck tumors and undergoing treatment in the Division of Radiotherapy at Santa Casa de Misericordia de Belo Horizonte, MG, Brazil, were selected. For their taste function testing, four solutions were manipulated with salt (NaCl), sugar (sucrose), citric acid (for acidity), and urea (for bitterness), at three different (low, medium and high) concentrations. Weekly tests were performed during the first three weeks of radiotherapy, with random administration of the solutions (three drops each) respecting the order of their concentration levels (low, medium and high). After the application of each solution, the patient reported which flavor he/she tasted. Results: a statistically significant difference was observed in the loss of taste function as the results in the 1st and 4th weeks of treatment were compared, with salty solution at the three concentration levels, with the sweet solution at low and medium concentrations, and with the sour and bitter solutions, only at low concentration. Conclusion: ionizing radiation alters the taste function of patients submitted to head and neck radiotherapy. (author)

  1. Effect of ionizing radiation on the taste function of patients submitted to head and neck radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Amaro Ilidio Vespasiano [Universidade Estadual de Campinas (UNICAMP), SP (Brazil); Galante, Celio [Santa Casa de Misericordia de Belo Horizonte, MG (Brazil). Div. de Radioterapia; Manzi, Flavio Ricardo, E-mail: manzi@pucminas.b [Pontificia Universidade Catolica de Minas Gerais (PUC-MG), Belo Horizonte, MG (Brazil)

    2011-09-15

    Objective: to evaluate the effects of ionizing radiation on the taste function in patients submitted to radiotherapy in the head and neck region. Materials and methods: twenty patients diagnosed with head and neck tumors and undergoing treatment in the Division of Radiotherapy at Santa Casa de Misericordia de Belo Horizonte, MG, Brazil, were selected. For their taste function testing, four solutions were manipulated with salt (NaCl), sugar (sucrose), citric acid (for acidity), and urea (for bitterness), at three different (low, medium and high) concentrations. Weekly tests were performed during the first three weeks of radiotherapy, with random administration of the solutions (three drops each) respecting the order of their concentration levels (low, medium and high). After the application of each solution, the patient reported which flavor he/she tasted. Results: a statistically significant difference was observed in the loss of taste function as the results in the 1st and 4th weeks of treatment were compared, with salty solution at the three concentration levels, with the sweet solution at low and medium concentrations, and with the sour and bitter solutions, only at low concentration. Conclusion: ionizing radiation alters the taste function of patients submitted to head and neck radiotherapy. (author)

  2. Infection by Cryptosporidium parvum in renal patients submitted to renal transplant or hemodialysis

    Directory of Open Access Journals (Sweden)

    Chieffi Pedro Paulo

    1998-01-01

    Full Text Available The frequency of infection by Cryptosporidium parvum was determined in two groups of renal patients submitted to immunosuppression. One group consisted of 23 renal transplanted individuals, and the other consisted of 32 patients with chronic renal insufficiency, periodically submitted to hemodialysis. A third group of 27 patients with systemic arterial hypertension, not immunosuppressed, was used as control. During a period of 18 months all the patients were submitted to faecal examination to detect C. parvum oocysts, for a total of 1 to 6 tests per patient. The results showed frequencies of C. parvum infection of 34.8%, 25% and 17.4%, respectively, for the renal transplanted group, the patients submitted to hemodialysis and the control group. Statistical analysis showed no significant differences among the three groups even though the frequency of C. parvum infection was higher in the transplanted group. However, when the number of fecal samples containing C. parvum oocysts was taken in account, a significantly higher frequency was found in the renal transplanted group.

  3. Computer information resources of inorganic chemistry and materials science

    International Nuclear Information System (INIS)

    Kiselyova, N N; Dudarev, V A; Zemskov, V S

    2010-01-01

    Information systems used in inorganic chemistry and materials science are considered. The following basic trends in the development of modern information systems in these areas are highlighted: access to information via the Internet, merging of documental and factual databases, involvement of experts in the evaluation of the data reliability, supplementing databases with information analysis tools on the properties of inorganic substances and materials.

  4. Computer information resources of inorganic chemistry and materials science

    Energy Technology Data Exchange (ETDEWEB)

    Kiselyova, N N; Dudarev, V A; Zemskov, V S [A.A.Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Moscow (Russian Federation)

    2010-02-28

    Information systems used in inorganic chemistry and materials science are considered. The following basic trends in the development of modern information systems in these areas are highlighted: access to information via the Internet, merging of documental and factual databases, involvement of experts in the evaluation of the data reliability, supplementing databases with information analysis tools on the properties of inorganic substances and materials.

  5. The Content of Mercury in Herbal Dietary Supplements.

    Science.gov (United States)

    Brodziak-Dopierała, Barbara; Fischer, Agnieszka; Szczelina, Wioletta; Stojko, Jerzy

    2018-01-17

    The dietary supplement market in Poland has been growing rapidly, and the number of registered products and their consumption increases steadily. Among the most popular and the easiest to get are herbal supplements, available in any supermarket. The aim of this paper was to investigate the mercury content in the herbal supplements. The dietary supplements that have been examined (24) are available on the Polish market and contain one or more herbal ingredients. Supplements were pulverized in porcelain mortar and identified by AMA 254 atomic absorption spectrometer. The range of variations for all tested supplements was within 0.02-4293.07 μg/kg. The arithmetic mean of the total result was 193.77 μg/kg. A higher mercury content then this mean was found in preparations-bamboo shoots and alga Chlorella pyrenoidosa. The studies have shown that mercury is present in every examined herbal supplement, and its content exceeds in two preparations (with bamboo and alga) the permissible limit of 0.10 mg/kg. There were statistically significant differences in the occurrence of mercury depending on the herbal ingredient in the supplement. The lowest content was found in the preparation with Tanacetum parthenium and the highest with bamboo shoots. The mercury content in the tested herbal supplements was statistically significant in the form of a supplement-a tablet and a capsule. Daily, weekly, monthly, and yearly consumption of mercury with examined supplements was calculated-the results did not exceed the PTWI-provisional tolerable weekly intake of mercury. To increase consumer safety, it is imperative to conduct further research on dietary supplements and implement a stricter quality control of the dietary supplements.

  6. Transport of radioactive materials

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1960-04-15

    The increasing use of radioactive substances, not only in reactor operations but also in medicine, industry and other fields, is making the movement of these materials progressively wider, more frequent and larger in volume. Although regulations for the safe transport of radioactive materials have been in existence for many years, it has now become necessary to modify or supplement the existing provisions on an international basis. It is essential that the regulations should be applied uniformly by all countries. It is also desirable that the basic regulations should be uniform for all modes of transport so as to simplify the procedures to be complied with by shippers and carriers

  7. 49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Published reports, material contained in the... OF RECORDS IN LEGAL PROCEEDINGS § 837.3 Published reports, material contained in the public accident... submitted, in writing, to the Public Inquiries Branch. Demands for specific published reports and studies...

  8. 18 CFR 344.2 - Manner of submitting quotations.

    Science.gov (United States)

    2010-04-01

    ... quotations. 344.2 Section 344.2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT FILING QUOTATIONS FOR U.S. GOVERNMENT SHIPMENTS AT REDUCED RATES § 344.2 Manner of submitting quotations. (a) The quotation or tender...

  9. Process of treating carbonaceous materials. [400 to 700/sup 0/C, high vacuum

    Energy Technology Data Exchange (ETDEWEB)

    Parker, O J

    1913-11-24

    A process is given of treating carbonaceous materials, characterized by the material being submitted simultaneously to a temperature of 400 to 700/sup 0/C, a pressure between 5.0 mm of mercury under atmospheric and a practically perfect vacuum, and by the volatile material able to condense under the vacuum used being condensed practically under the same pressure for the production of a high proportion of condensable products and a superior fuel.

  10. Analysis of suspected wildlife crimes submitted for forensic examinations in Scotland.

    Science.gov (United States)

    Millins, Caroline; Howie, Fiona; Everitt, Charles; Shand, Michael; Lamm, Catherine

    2014-09-01

    This study describes the occurrence of suspected wildlife crimes submitted for forensic examination in Scotland in 2010. The study aims were to determine which types of crimes were committed, which species were targeted, and the outcome of investigations, in order to assess the contribution of forensic examinations in the prosecution of wildlife crimes. Information on suspected wildlife crimes submitted between January 1 and December 31, 2010 to the SAC Consulting: Veterinary Services Disease Surveillance Centers, Science and Advice for Scottish Agriculture, and to the University of Glasgow, was used. The location of suspected crimes, the species targeted, cause of death, and types of the 188 submitted wildlife crimes were summarized. More information regarding cases involving birds were submitted than cases involving mammals, and included 114 raptors, 14 waterfowl, and 22 "other bird species." Mammal cases (n = 38) included 12 badgers, 8 foxes, 7 deer, 4 hares, and 7 "other mammals." The cause of death was determined in 124 suspected crimes; malicious or accidental trauma was the most likely cause of death in 72, and 33 were poisoned. Forensic evidence supporting criminal activity was found in 53 cases, and poisoning was the most frequent crime recorded. At least five individuals were successfully prosecuted, representing 2.7 % of submissions. It was challenging to track cases from submission through to prosecution and laboratories conducting forensic investigations were often not informed of the outcome of prosecutions or court decisions.

  11. 2017 Annual Disability Statistics Supplement

    Science.gov (United States)

    Lauer, E. A; Houtenville, A. J.

    2018-01-01

    The "Annual Disability Statistics Supplement" is a companion report to the "Annual Disability Statistics Compendium." The "Supplement" presents statistics on the same topics as the "Compendium," with additional categorizations by demographic characteristics including age, gender and race/ethnicity. In…

  12. Supplemental information

    Data.gov (United States)

    U.S. Environmental Protection Agency — Supplemental information showing results of inter-comparison between C-PORT, AERMOD and R-LINE dispersion algorithms. This dataset is associated with the following...

  13. Arterial hypertension and associated factors in patients submitted to myocardial revascularization

    Directory of Open Access Journals (Sweden)

    Flávia Cortez Colósimo

    2015-04-01

    Full Text Available OBJECTIVE To identify the prevalence of arterial hypertension and associated factors in patients submitted to myocardial revascularization. METHOD Cross-sectional study using the database of a hospital in São Paulo (SP, Brazil containing 3010 patients with coronary artery disease submitted to myocardial revascularization. A multiple logistic regression was performed to identify variables independently associated with hypertension (statistical significance: p1.3: (OR=1.37;CI:1.09-1.72. CONCLUSION A high prevalence of arterial hypertension and association with both non-modifiable and modifiable factors was observed.

  14. Stress analysis in pipelines submitted to internal pressure - and temperature transients

    International Nuclear Information System (INIS)

    Mansur, T.R.

    1981-08-01

    Experimental determination of the structural behaviour of a thermal-hydraulic loop, when submitted to simultaneous fast change of pressure and temperature, was performed. For this, electrical strain-gages were positioned at some critical points in order to measure the deformation conditions of the structure. The study of the kinetics of the deformation revealed the presence of important transient stresses, mainly from thermal origin. After this transient behaviour, the structure is submitted to a thermal stress, which is shown to be strongly dependent on the degree of restraint of the structure. (Author) [pt

  15. 42 CFR 403.220 - Supplemental Health Insurance Panel.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Supplemental Health Insurance Panel. 403.220... Programs § 403.220 Supplemental Health Insurance Panel. (a) Membership. The Supplemental Health Insurance... determines whether or not a State regulatory program for Medicare supplemental health insurance policies...

  16. Ingestive behavior of supplemented Nellore heifers grazing palisadegrass pastures managed with different sward heights.

    Science.gov (United States)

    Vieira, Bruno Ramalho; Azenha, Mariana Vieira; Casagrande, Daniel Rume; Costa, Diogo Fleury Azevedo; Ruggieri, Ana Cláudia; Berchielli, Telma Teresinha; Reis, Ricardo Andrade

    2017-04-01

    Three sward heights (15, 25 and 35 cm) and three supplement types (energy, energy-protein, and a mineral mix supplement) were evaluated in a 3 × 3 factorial arrangement distributed in a completely randomized design to study changes in forage search patterns in Nellore heifers in a continuous grazing system. Pasture data were collected using two replicates (paddocks) per treatment over four periods during the rainy season. The behavior assessments were made in the first and fourth grazing seasons. It was hypothesized that supplements and pasture management would modify ingestive behavior, considering that animals would require less time grazing if they had energy requirements met through higher digestibility of better managed paddocks, or use of supplements high in energy. Total and green forage masses along with green : dead material ratio were greater in treatments managed with higher sward heights. Sward managed with 35 cm height resulted in lower leaf : stem ratio compared with 15 cm sward height treatments. The animals on the 15 cm pastures spent more time grazing overall and during each meal, but there were no differences observed in meal numbers in comparison to 35 cm treatments. Heifers fed protein and/or energy supplements spent less time grazing in the early afternoon, but overall grazing time was the same for all animals. © 2016 Japanese Society of Animal Science.

  17. Protecting military personnel from high risk dietary supplements.

    Science.gov (United States)

    Deuster, Patricia A; Lieberman, Harris R

    2016-01-01

    It is legal tomarketmost naturally occurring substances as dietary supplements in the USA without manufacturers demonstrating they are safe or effective, and an endless variety of ingredients, from esoteric botanicals to unapproved pharmaceuticals, can be found in dietary supplements. Use of certain supplements can pose a risk, but since a robust reporting systemdoes not exist in the USA it is difficult to know which are problematic and the number of adverse events (AE) resulting from their use. Certain populations, includingmilitary personnel, aremore likely to use dietary supplements than the general population. Approximately 70% of military personnel take dietary supplements while about 50% of civilians do. Service members prefer supplements purported to enhance physical performance such as supposedly natural stimulants, protein and amino acids, and combination products. Since some of thesemay be problematic, Servicemembers are probably at higher risk of injury than the general population. Ten percent of military populations appear to be taking potentially risky supplements, and the US Department of Defense (DoD) has taken variousmeasures to protect uniformed personnel including education, policy changes, and restricting sales. Actions taken include launching Operation Supplement Safety (OPSS), introducing a High Risk Supplement list, educating health care professionals on reporting AE thatmight be associated with dietary supplements, recommending policy for reporting AE, and developing an online AE reporting system. OPSS is a DoD-wide effort to educate service members, leaders, health care providers, military families, and retirees on how to safely select supplements

  18. 17 CFR 145.9 - Petition for confidential treatment of information submitted to the Commission.

    Science.gov (United States)

    2010-04-01

    ... may summarily reject the submitter's request for confidential treatment with leave to the submitter to... treatment of information submitted to the Commission. 145.9 Section 145.9 Commodity and Securities Exchanges... treatment of information submitted to the Commission. (a) Purpose. This section provides a procedure by...

  19. 78 FR 63501 - Request To Submit a Two-Part Application-Northwest Medical Isotopes, LLC

    Science.gov (United States)

    2013-10-24

    ... new accident precursors are created by allowing an applicant to submit a construction permit... certain regulatory requirements, which, if granted, would allow the submittal of a construction permit... facility applicants subject to 10 CFR 51.20(b) \\1\\ may submit the information required for a construction...

  20. Nuclear fuel reprocessing and high level waste disposal: informational hearings. Volume XII. Public and private roles, Part 2

    International Nuclear Information System (INIS)

    1977-01-01

    Presentations were made on institutional experiences at Nuclear Fuel Services, the framework for an acceptable nuclear future, the Price-Anderson Indemnity Act, Congress and nuclear energy policy, human dimension, and risk perception. The supplemental testimony and materials submitted for the record included information of the nuclear waste at West Valley, New York, the perception and acceptability of risk from nuclear and alternative energy sources, and psychological determinants of perceived and acceptable risk

  1. CREATINE SUPPLEMENTATION AND SWIM PERFORMANCE: A BRIEF REVIEW

    Directory of Open Access Journals (Sweden)

    Melissa J. Hopwood

    2006-03-01

    Full Text Available Nutritional supplements are popular among athletes participating in a wide variety of sports. Creatine is one of the most commonly used dietary supplements, as it has been shown to be beneficial in improving performance during repeated bouts of high-intensity anaerobic activity. This review examines the specific effects of creatine supplementation on swimming performance, and considers the effects of creatine supplementation on various measures of power development in this population. Research performed on the effect of creatine supplementation on swimming performance indicates that whilst creatine supplementation is ineffective in improving performance during a single sprint swim, dietary creatine supplementation may benefit repeated interval swim set performance. Considering the relationship between sprint swimming performance and measurements of power, the effect of creatine supplementation on power development in swimmers has also been examined. When measured on a swim bench ergometer, power development does show some improvement following a creatine supplementation regime. How this improvement in power output transfers to performance in the pool is uncertain. Although some evidence exists to suggest a gender effect on the performance improvements seen in swimmers following creatine supplementation, the majority of research indicates that male and female swimmers respond equally to supplementation. A major limitation to previous research is the lack of consideration given to the possible stroke dependant effect of creatine supplementation on swimming performance. The majority of the research conducted to date has involved examination of the freestyle swimming stroke only. The potential for performance improvements in the breaststroke and butterfly swimming strokes is discussed, with regards to the biomechanical differences and differences in efficiency between these strokes and freestyle

  2. The Effect of Zinc Supplementation on Cognitive Performance in Schoolchildren

    Directory of Open Access Journals (Sweden)

    Ezzat Khodashenas

    2015-11-01

    Full Text Available Introduction Zinc is a vital micronutrient in humans and its deficiency in children can thwart their growth and development, compromise their immunity and cognitive function. However, there is a paucity of studies about the effect of zinc supplementation on cognitive functions. This study is an attempt to quantify the impact of zinc supplementation on cognitive performance of schoolchildren. Materials and Methods This randomized, double-blind, placebo-controlled field trial was carried out in public elementary school in Mashhad- Iran to investigate the effect of Zinc on cognition of 45 healthy children. The cognitive test used in the trial was Raven IQ (Intelligence Quotient test. A total of 45 first grade children aged 6 to 8 years were enrolled and divided into two experiment and control groups. The cases group, received 20 mg of zinc sulfate syrup vs.  the control group  received a placebo each day for 6 months. Raven IQ test was administered under basal conditions before and after the supplementation of zinc or placebo. Results The memory and intellectual development in the experimental group was significantly more than in the control group (P < 0.05. Conclusion The results of the study demonstrate the positive relationship between zinc administration and some aspects of intellectual development and personality features, emphasizing the significance of this element in the normal psychological status of children.

  3. Mineral supplementation in Tunisian smallholder dairy farms

    International Nuclear Information System (INIS)

    Rekhis, J.; Kouki-Chebbi, K.; Dhaouadi, B.; Khlif, K.

    2002-01-01

    The aim of the experiment was to determine the effects of supplementation of di-calcium-phosphate in the form of blocks in late pregnancy (2 months before calving), on production and reproduction parameters of dairy cattle in smallholder farms. The experiment covered 63 animals in 20 smallholder farms, divided into control and supplemented groups. Results showed that mineral supplementation had a significant effect on calf weight, milk fat content and reproduction parameters. Calves born to cattle supplemented with di-calcium-phosphate were heavier by 1.67 kg than those in the control group. Similarly, the average milk fat content in the supplemented group was 5.6 g/L (P 0.05). (author)

  4. Supplements in pregnancy: the latest recommendations

    Science.gov (United States)

    Martínez García, Rosa María

    2016-07-12

    Pregnancy is a challenge from the nutritional point of view, because nutrient requirements are increased and alter its intake can affect maternal and fetal health. Micronutrient defi ciency states are related to preeclampsia, intrauterine growth restriction, abortion and congenital anomalies. Currently, the diet of many expectant mothers is insufficient in micronutrients, in this cases supplementation is necessary. It is recommended supplementation with folic acid in doses of 400 mcg / day and 5 mg/day in risk pregnant, and should begin at least one month before conception and during the first 12 weeks gestation, and extend it throughout pregnancy in mothers with nutritional risk. It is important to keep watch the proper dose of folic acid to prevent possible adverse effects of unmetabolized accumulation in plasma. A high percentage of pregnant women presented iron deficiency anemia, being recommended intermittent use of iron supplements (with lower gastrointestinal alteration and oxidative stress); not recommended for mothers without anemia (hemoglobin> 13.5 g / L). Since calcium absorption is increased up to 40% in gestation, its supplementation is not recommended for mothers with adequate intakes (3 dairy / day), and its use must be reserved to women with inadequate intakes and / or high risk of preeclampsia. Regarding the iodine, there are confl icting positions by different working groups established potassium iodide supplementation in women who do not reach their recommended intake (3 servings of milk and dairy products + 2 g of iodized salt), with their diets. Given that vitamin A and D can be toxic to mother and fetus, it is not recommended its supplementation except in cases of deficiency. Although the use of multiple micronutrients supplements may favorably impact the outcome of pregnancy, more scientific evidence is needed to establish the replacement of iron and folic acid with a multiple micronutrient supplement.

  5. Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation.

    Science.gov (United States)

    Chan, D; McGraw, S; Klein, K; Wallock, L M; Konermann, C; Plass, C; Chan, P; Robaire, B; Jacob, R A; Greenwood, C M T; Trasler, J M

    2017-02-01

    , no significant changes were observed in individual probes following low-level supplementation; when compared with those of the post-fortification cohort, there were also few differences in methylation despite exposure to years of fortified foods. Illumina HumanMethylation450 BeadChip data from this study have been submitted to the NCBI Gene Expression Omnibus under the accession number GSE89781. This study was limited to the number of participants available in each cohort, in particular those who were not exposed to early (pre-1998) fortification of food with folic acid. While genome-wide DNA methylation was assessed with several techniques that targeted genic and CpG-rich regions, intergenic regions were less well interrogated. Overall, our findings provide evidence that short-term exposure to low-dose folic acid supplements of 400 μg/day, over a period of 3 months, a duration of time that might occur during infertility treatments, has no major impact on the sperm DNA methylome. This work was supported by a grant to J.M.T. from the Canadian Institutes of Health Research (CIHR: MOP-89944). The authors have no conflicts of interest to declare. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  6. Fluid supplementation for neonatal unconjugated hyperbilirubinaemia.

    Science.gov (United States)

    Lai, Nai Ming; Ahmad Kamar, Azanna; Choo, Yao Mun; Kong, Juin Yee; Ngim, Chin Fang

    2017-08-01

    Neonatal hyperbilirubinaemia is a common problem which carries a risk of neurotoxicity. Certain infants who have hyperbilirubinaemia develop bilirubin encephalopathy and kernicterus which may lead to long-term disability. Phototherapy is currently the mainstay of treatment for neonatal hyperbilirubinaemia. Among the adjunctive measures to compliment the effects of phototherapy, fluid supplementation has been proposed to reduce serum bilirubin levels. The mechanism of action proposed includes direct dilutional effects of intravenous (IV) fluids, or enhancement of peristalsis to reduce enterohepatic circulation by oral fluid supplementation. To assess the risks and benefits of fluid supplementation compared to standard fluid management in term and preterm newborn infants with unconjugated hyperbilirubinaemia who require phototherapy. We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 5), MEDLINE via PubMed (1966 to 7 June 2017), Embase (1980 to 7 June 2017), and CINAHL (1982 to 7 June 2017). We also searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles for randomised controlled trials and quasi-randomised trials. We included randomised controlled trials that compared fluid supplementation against no fluid supplementation, or one form of fluid supplementation against another. We extracted data using the standard methods of the Cochrane Neonatal Review Group using the Covidence platform. Two review authors independently assessed the eligibility and risk of bias of the retrieved records. We expressed our results using mean difference (MD), risk difference (RD), and risk ratio (RR) with 95% confidence intervals (CIs). Out of 1449 articles screened, seven studies were included. Three articles were awaiting classification, among them, two completed trials identified from the trial registry appeared to be unpublished so far.There were

  7. Special requirements for bolting material for nuclear and other special applications

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    A specification that provides special requirements for bolting material for use in nuclear and other special applications is presented. The requirements of the specification are supplemental to the requirements of the basic material specifications and they include tempering, welding, elimination of surface defects, certification and identification, quality assurance and various examination methods

  8. Diffraction analysis of materials under strong plastic deformation

    International Nuclear Information System (INIS)

    Pyzalla, A.

    2001-01-01

    The applicability of X-ray diffraction in analyses of the microstructure texture and intrinsic stresses of materials under strong plastic deformation is illustrated by examples and discussed. The experimental methods and findings are supplemented by numeric calculations. It is shown how the microstructure, texture and intrinsic stresses can thus be optimized already in the production process. Analyses of changes in materials during operation of a component provide information on loads and material response to loads which can then be used for optimization of the component, e.g. by constructional modifications or selective heat treatment [de

  9. Weakly distributive modules. Applications to supplement submodules

    Indian Academy of Sciences (India)

    Abstract. In this paper, we define and study weakly distributive modules as a proper generalization of distributive modules. We prove that, weakly distributive supplemented modules are amply supplemented. In a weakly distributive supplemented module every submodule has a unique coclosure. This generalizes a result of ...

  10. Theoretical Synthesis of Mixed Materials for CO2 Capture Applications

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Yuhua

    2015-01-01

    These pages provide an example of the layout and style required for the preparation of four-page papers for the TechConnect World 2015 technical proceedings.Documents must be submitted in electronic (Adobe PDFfile) format. Please study the enclosed materials beforebeginning the final preparation of your paper. Proofread your paper carefully before submitting (it will appear in the published volume in exactly the same form). Your PDF manuscript must be uploaded online by April 11th, 2015.You will receive no proofs. Begin your paper with an abstract of no more than 18 lines. Thoroughly summarize your article in this section since this text will be used for on-line listing and classification of the publication.

  11. 41 CFR 105-50.402 - Reports submitted to the Office of Management and Budget.

    Science.gov (United States)

    2010-07-01

    ... Office of Management and Budget. 105-50.402 Section 105-50.402 Public Contracts and Property Management... submitted to the Office of Management and Budget. Copies of the foregoing reports will be submitted by the Administrator to the Office of Management and Budget not later than March 30 of each year. ...

  12. Effect of dietary supplementation with Lactobacillus acidophilus D2/CSL (CECT 4529 on caecum microbioma and productive performance in broiler chickens.

    Directory of Open Access Journals (Sweden)

    Alessandra De Cesare

    Full Text Available This study examines the effects of the dietary supplementation with Lactobacillus acidophilus D2/CSL (CECT 4529 (LA on productive performances, incidence of foot pad dermatitis and caecum microbioma in broiler chickens. A total of 1,100 one-day old male Ross 308 chicks were divided into 2 groups of 16 replicates with 25 birds each and reared from 1-41 d. One group was fed a basal diet (CON and the other group the same diet supplemented with LA. Caecum contents were collected from 4 selected birds at day one and 5 selected birds at the end of the rearing period. Then, they were submitted to DNA extraction and whole DNA shotgun metagenomic sequencing. Overall, the LA supplementation produced a significant beneficial effect on body weight gain between 15-28 d and improved feed conversion rate in the overall period. On the contrary, litter moisture, pH and incidence of the foot pad lesions were not affected by LA. Birds treated with LA showed a lower occurrence of pasty vent at both 14 and 28 d. At the end of the rearing period, Lachanospiraceae were significantly higher in LA birds in comparison to CON (17.07 vs 14.39%; P = 0.036. Moreover, Ruminococcus obeum, Clostridium clostridioforme, Roseburia intestinalis, Lachnospiraceae bacterium 14-2T and Coprococcus eutactus were significantly higher in LA birds in comparison to CON. The relative abundance of Lactobacillus acidophilus was comparable between LA and CON groups. However, a positive effect was observed in relation to the metabolic functions in the treated group, with particular reference to the higher abundance of β-glucosidase. In conclusion, the LA supplementation improved broiler productive performances and metabolic functions promoting animal health.

  13. Effect of dietary supplementation with Lactobacillus acidophilus D2/CSL (CECT 4529) on caecum microbioma and productive performance in broiler chickens.

    Science.gov (United States)

    De Cesare, Alessandra; Sirri, Federico; Manfreda, Gerardo; Moniaci, Paola; Giardini, Alberto; Zampiga, Marco; Meluzzi, Adele

    2017-01-01

    This study examines the effects of the dietary supplementation with Lactobacillus acidophilus D2/CSL (CECT 4529) (LA) on productive performances, incidence of foot pad dermatitis and caecum microbioma in broiler chickens. A total of 1,100 one-day old male Ross 308 chicks were divided into 2 groups of 16 replicates with 25 birds each and reared from 1-41 d. One group was fed a basal diet (CON) and the other group the same diet supplemented with LA. Caecum contents were collected from 4 selected birds at day one and 5 selected birds at the end of the rearing period. Then, they were submitted to DNA extraction and whole DNA shotgun metagenomic sequencing. Overall, the LA supplementation produced a significant beneficial effect on body weight gain between 15-28 d and improved feed conversion rate in the overall period. On the contrary, litter moisture, pH and incidence of the foot pad lesions were not affected by LA. Birds treated with LA showed a lower occurrence of pasty vent at both 14 and 28 d. At the end of the rearing period, Lachanospiraceae were significantly higher in LA birds in comparison to CON (17.07 vs 14.39%; P = 0.036). Moreover, Ruminococcus obeum, Clostridium clostridioforme, Roseburia intestinalis, Lachnospiraceae bacterium 14-2T and Coprococcus eutactus were significantly higher in LA birds in comparison to CON. The relative abundance of Lactobacillus acidophilus was comparable between LA and CON groups. However, a positive effect was observed in relation to the metabolic functions in the treated group, with particular reference to the higher abundance of β-glucosidase. In conclusion, the LA supplementation improved broiler productive performances and metabolic functions promoting animal health.

  14. Rectal dose assessment in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer; Avaliacao da dose no reto em pacientes submetidas a braquiterapia de alta taxa de dose para o tratamento do cancer do colo uterino

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Jetro Pereira de [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Faculdade de Medicina; Rosa, Luiz Antonio Ribeiro da [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)], e-mail: lrosa@ird.gov.br; Batista, Delano Valdivino Santos; Bardella, Lucia Helena [Instituto Nacional de Cancer (INCA), Rio de Janeiro, RJ (Brazil). Unit of Medical Physics; Carvalho, Arnaldo Rangel [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Lab. of Thermoluminescent Dosimetry

    2009-03-15

    Objective: The present study was aimed at developing a thermoluminescent dosimetric system capable of assessing the doses delivered to the rectum of patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. Materials and methods: LiF:Mg,Ti,Na powder was the thermoluminescent material utilized for evaluating the rectal dose. The powder was divided into small portions (34 mg) which were accommodated in a capillary tube. This tube was placed into a rectal probe that was introduced into the patient's rectum. Results: The doses delivered to the rectum of six patients submitted to high-dose-rate brachytherapy for uterine cervix cancer evaluated by means of thermoluminescent dosimeters presented a good agreement with the planned values based on two orthogonal (anteroposterior and lateral) radiographic images of the patients. Conclusion: The thermoluminescent dosimetric system developed in the present study is simple and easy to be utilized as compared to other rectal dosimetry methods. The system has shown to be effective in the evaluation of rectal doses in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. (author)

  15. Supplemental Release Limits for the Directed Reuse of Lead in Shielding Products by the Department of Energy

    International Nuclear Information System (INIS)

    Coleman, R.L.

    2001-01-01

    The DOE National Center of Excellence for Metals Recycle (NMR) proposes to define and implement a complex-wide directed reuse strategy for surplus radiologically impacted lead (Pb) as part of the U.S. Department of Energy's commitment to the safe and cost-effective recycle or reuse of excess materials and equipment across the DOE complex. NMR will, under this proposal, act on behalf of the DOE Office of Environmental Management, Office of Technical Program Integration (specifically EM-22), as the Department's clearinghouse for DOE surplus lead and lead products by developing and maintaining a cost-effective commercially-based contaminated lead recycle program. It is NMR's intention, through this directed reuse strategy, to mitigate the adverse environmental and economic consequences of managing surplus lead as a waste within the complex. This approach would promote the safe and cost-effective reuse of DOE's scrap and surplus lead in support of the Department's goals of resource utilization, energy conservation, pollution prevention and waste minimization. This report discusses recommendations for supplemental radiological limits for the directed reuse of contaminated lead and lead products by the DOE within the nuclear industry. The limits were selected--with slight modification--from the recently published American National Standards Institute and Health Physics Society standard N13.12 titled Surface and Volume Radioactivity Standards for Clearance (ANSI/HPS 1999) and are being submitted for formal approval by the DOE. Health and measurement implications from the adoption and use of the limits for directed reuse scenarios are discussed within this report

  16. Supplemental Release Limits for the Directed Reuse of Lead in Shielding Products by the Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, R.L.

    2001-08-22

    The DOE National Center of Excellence for Metals Recycle (NMR) proposes to define and implement a complex-wide directed reuse strategy for surplus radiologically impacted lead (Pb) as part of the U.S. Department of Energy's commitment to the safe and cost-effective recycle or reuse of excess materials and equipment across the DOE complex. NMR will, under this proposal, act on behalf of the DOE Office of Environmental Management, Office of Technical Program Integration (specifically EM-22), as the Department's clearinghouse for DOE surplus lead and lead products by developing and maintaining a cost-effective commercially-based contaminated lead recycle program. It is NMR's intention, through this directed reuse strategy, to mitigate the adverse environmental and economic consequences of managing surplus lead as a waste within the complex. This approach would promote the safe and cost-effective reuse of DOE's scrap and surplus lead in support of the Department's goals of resource utilization, energy conservation, pollution prevention and waste minimization. This report discusses recommendations for supplemental radiological limits for the directed reuse of contaminated lead and lead products by the DOE within the nuclear industry. The limits were selected--with slight modification--from the recently published American National Standards Institute and Health Physics Society standard N13.12 titled Surface and Volume Radioactivity Standards for Clearance (ANSI/HPS 1999) and are being submitted for formal approval by the DOE. Health and measurement implications from the adoption and use of the limits for directed reuse scenarios are discussed within this report.

  17. THE STUDY OF FISH SUPPLEMENT AND BUTTERFAT SUBSTITUTE EFFECT ON EXPIRY DATE OF PROCESSED CHEESE PRODUCT

    Directory of Open Access Journals (Sweden)

    NATALIYA LOTYSH

    2015-02-01

    Full Text Available The sector of functional products has top-priority meaning – it is the most convenient and natural form of introduction and enrichment of the human organism with vitamins, mineral substances, microelements and other components. Attraction into the branch of raw materials of non-milk origin – fish supplements and substitutes of butterfat – served the basis of technology development of processed cheese products of combined content, which in accordance with acting terminology are called processed cheese products. The technology of processed cheese products allows easily regulating their content by introduction of corresponding supplement that facilitates obtainment of product with set properties and content. Inclusion of meat and fish as the raw materials in the processed cheese content results in enrichment of the product with macro- and microelements, unsaturated fatty acids, except for regulation of fatty acid content of cheese products is executed by substitution of butterfat by butterfat substitute.

  18. Problems and Prospects: Public Health Regulation of Dietary Supplements.

    Science.gov (United States)

    Binns, Colin W; Lee, Mi Kyung; Lee, Andy H

    2018-04-01

    Dietary supplements are a global business worth more than US$100 billion annually. These supplements are taken by up to 50% of adults and perhaps one-third of children in economically advanced economies. Definitions of dietary supplements differ from country to country, and regulation is generally lax and often seems to be directed more toward promoting commerce than protecting public health. Supplements may directly cause toxic reactions or may interact with other supplements or pharmaceuticals. Some supplements are found to have been contaminated with heavy metals, and others do not contain the expected quantities of active ingredients. In general, supplements are not needed except in cases of established deficiencies, and excess of some nutrients can increase cancer rates. There are important public health reasons for taking some supplements, including folate and iodine in pregnancy. This review discusses the public health concerns associated with dietary supplements and suggests directions for further regulation.

  19. An overview of herb and dietary supplement efficacy, safety and government regulations in the United States with suggested improvements. Part 1 of 5 series.

    Science.gov (United States)

    Brown, Amy Christine

    2017-09-01

    This is the first of five review articles investigating dietary supplements (DS; includes herbs) that now exceed over 50,000 in the Office of Dietary Supplement's "Dietary Supplement Label Database." Four review articles follow summarizing published medical case reports of DS related to liver toxicity, kidney toxicity, heart toxicity, and cancer. The most popular DS were vitamin or mineral supplements (43%) followed by specialty supplements (20%), botanicals (20%; herbs), and sports supplements (16%). The 2013 Annual Report of the American Association of Poison Control Centers revealed 1692 fatalities due to drugs, and zero deaths due to DS. Less than 1 percent of Americans experience adverse events related to DS, and the majority was classified as minor, with many of these related to caffeine, yohimbe, or other stimulant ingredients. The number one adulterant in DS is drugs, followed by New Dietary Ingredients (NDI) not submitted to the FDA - both are illegal and not DS, but rather "tainted products marketed as dietary supplements." The three main categories of DS prone to medical problems are those for sexual enhancement, weight loss, and sports performance/body building. DS are regulated in the U.S. by several federal agencies with overlapping jurisdiction - the Food and Drug Administration (FDA) and the Federal Trade Commission (FTC); enforced by the State Attorneys General Offices (AGO) and Department of Justice (DOJ); and monitored (not regulated) by the Centers for Disease Control and Prevention (CDC). The FDA can remove a DS from the market for phase IV post-marketing surveillance adverse event reports, adulteration (drugs, NDI, synthetic substances), contamination, misidentification, mislabeling or false claims, and not meeting good manufacturing practices (GMP). The FTC and state AGO can also enforce laws against deceptive marketing practices. Suggested improvements to current regulatory requirements are included along with online DS Toxic Tables in the

  20. 20 CFR 703.105 - Copies of forms of policies to be submitted with application.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Copies of forms of policies to be submitted... REGULATIONS Authorization of Insurance Carriers § 703.105 Copies of forms of policies to be submitted with... of the Office copies of the forms of policies which the applicant proposes to issue in writing...

  1. 78 FR 76293 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-12-17

    ... Environmental Protection Agency has submitted an information collection request (ICR), ``Performance Evaluation... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OECA-2013-0547; FRL 9903-29-OEI] Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Performance Evaluation Studies on...

  2. Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements.

    Science.gov (United States)

    Jaworska, Karolina; Krynitsky, Alexander J; Rader, Jeanne I

    2012-01-01

    Simultaneous separation of steviol and steviol glycosides is challenging because of differences in their polarity and chemical structure. In this study, simultaneous analysis of steviol and steviol glycosides was achieved by LC with UV detection using a mixed-mode RP weak anion exchange chromatography column. Steviol and seven steviol glycosides were analyzed on an Acclaim Mixed-Mode Wax-1 (Dionex) column with a linear gradient of deionized water adjusted to pH 3.00 with phosphoric acid and acetonitrile. The extraction was performed by sonicating dry plant material at 40 degreesC in acetonitrile-water (30 + 70, v/v). LOQ values (mg/g dry weight of plant material) were rebaudioside B, 0.50; steviol, 0.70, dulcoside A, 1.0; steviolbioside, 1.2; stevioside and rebaudioside C, 2.0; rebaudioside D, 3.3; and rebaudioside A, 5.0. The method demonstrated suitable performance for all analytes tested with respect to accuracy (mean recoveries 95-99%), intraday and interday precision for retention times (0.070-0.28% and 0.33-1.0% RSD, respectively), and linearity. The method was used to authenticate steviol glycosides in several samples of Stevia plant material as well as to quantitate steviol glycosides in dietary supplements containing Stevia.

  3. Efficacy of supplementation in filipino children.

    Science.gov (United States)

    Tayao, Charisse Marie S

    2015-01-01

    At present, in the absence of an anemia prevention and screening program in Barangay Vasra, this will aid in the formation of programs that would teach about this health related issue, with an intervention that could be used efficiently by the health workers at the non-government organization run center. The aim of the following study is to establish the efficacy of iron supplementation alone versus iron and ascorbic acid supplementation in improving the hemoglobin (Hgb), hematocrit (Hct), reticulocyte count and red cell indices of anemic undernourished children 5-10 years of age at Lingap Center, Barangay Vasra, Quezon City. Anemic undernourished male and female children 5-10 years of age enrolled in the Supplementary Feeding Program of Lingap Center, Barangay Vasra, Quezon City. Prospective, experimental trial comparing two interventions-iron supplementation alone versus iron and ascorbic acid supplementation. A total of 25 children participated in this study, with a majority being female at 52% (13/25) of the total. Those who received iron supplementation alone for 6 months, while there were 50% (6/12) of either sex, whereas subjects who took iron and ascorbic acid supplementation for 6 months were predominantly female at 53.85% (7/13). Data obtained before and after iron supplementation alone revealed that there was an increase among the levels of Hgb, Hct, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and reticulocyte count, with the rise statistically significant. Hematological values gained before and after iron and ascorbic acid supplementation uncovered that there was an augmentation among the levels of Hct, MCV, MCH, MCHC and reticulocyte count, with the improvement statistically significant. Encompassing both interventions, the differences in findings were statistically significant in red blood cell (RBC) count, with the level progression statistically significant. Overall, the results

  4. Efficacy of supplementation in Filipino children

    Directory of Open Access Journals (Sweden)

    Charisse Marie S Tayao

    2015-01-01

    Full Text Available Introduction: At present, in the absence of an anemia prevention and screening program in Barangay Vasra, this will aid in the formation of programs that would teach about this health related issue, with an intervention that could be used efficiently by the health workers at the non-government organization run center. Objective: The aim of the following study is to establish the efficacy of iron supplementation alone versus iron and ascorbic acid supplementation in improving the hemoglobin (Hgb, hematocrit (Hct, reticulocyte count and red cell indices of anemic undernourished children 5-10 years of age at Lingap Center, Barangay Vasra, Quezon City. Methodology: Anemic undernourished male and female children 5-10 years of age enrolled in the Supplementary Feeding Program of Lingap Center, Barangay Vasra, Quezon City. Study Design: Prospective, experimental trial comparing two interventions-iron supplementation alone versus iron and ascorbic acid supplementation. Results: A total of 25 children participated in this study, with a majority being female at 52% (13/25 of the total. Those who received iron supplementation alone for 6 months, while there were 50% (6/12 of either sex, whereas subjects who took iron and ascorbic acid supplementation for 6 months were predominantly female at 53.85% (7/13. Data obtained before and after iron supplementation alone revealed that there was an increase among the levels of Hgb, Hct, mean corpuscular volume (MCV, mean corpuscular hemoglobin (MCH, mean corpuscular hemoglobin concentration (MCHC and reticulocyte count, with the rise statistically significant. Hematological values gained before and after iron and ascorbic acid supplementation uncovered that there was an augmentation among the levels of Hct, MCV, MCH, MCHC and reticulocyte count, with the improvement statistically significant. Encompassing both interventions, the differences in findings were statistically significant in red blood cell (RBC count

  5. 21 CFR 1304.31 - Reports from manufacturers importing narcotic raw material.

    Science.gov (United States)

    2010-04-01

    ... therefrom. (g) All in-process inventories should be expressed in terms of end-products and not precursors... following information shall be submitted for each type of narcotic raw material (quantities are expressed as... opium, crude alkaloids and other derivatives (quantities are expressed as grams of anhydrous base or...

  6. Micronutrient Supplement Use and Diet Quality in University Students

    Directory of Open Access Journals (Sweden)

    Adam R. Wiltgren

    2015-02-01

    Full Text Available Many national and international public health organisations recommend achieving nutrient adequacy through consumption of a wide variety of nutritious foods. Despite this, dietary supplement sales continue to increase. Understanding the characteristics of micronutrient supplement users and the relationship with diet quality can help develop effective public health interventions to reduce unnecessary consumption of vitamin and mineral supplements. Participants (n = 1306 were a convenience sample of students studying first year food and nutrition. Data was collected via a Food and Diet Questionnaire (FDQ and a Food Frequency Questionnaire (FFQ. Supplement users were defined as participants who indicated consuming any listed supplement as frequently as once a month or more. Diet quality was assessed using a Dietary Guideline Index (DGI score. Prevalence of supplement use was high in this study population with 56% of participants reporting supplement use; the most popular supplements consumed were multivitamins (28% and vitamin C (28%. A higher DGI score was significantly associated with an increased likelihood of supplement use (mean: 105 ± 18 vs. 109 ± 17, p = 0.001. Micronutrient supplement use was associated with a higher DGI score, suggesting that supplements are more likely to be used by those who are less likely to require them.

  7. Site Decommissioning Management Plan. Supplement 1

    International Nuclear Information System (INIS)

    Fauver, D.N.; Weber, M.F.; Johnson, T.C.; Kinneman, J.D.

    1995-11-01

    The Nuclear Regulatory Commission (NRC) staff has identified 51 sites contaminated with radioactive material that require special attention to ensure timely decommissioning. While none of these sites represent an immediate threat to public health and safety, they have contamination that exceeds existing NRC criteria for unrestricted use. All of these sites require some degree of remediation, and several involve regulatory issues that must be addressed by the Commission before they can be released for unrestricted use and the applicable licenses terminated. This report contains the NRC stairs strategy for addressing the technical, legal, and policy issues affecting the timely decommissioning of the 51 sites and describes the status of decommissioning activities at the sites. This is supplement number one to NUREG-1444, which was published in October 1993

  8. Safety evaluation report related to the operation of Sequoyah Nuclear Plant, Units 1 and 2, Docket Nos. 50-327 and 50-328, Tennessee Valley Authority. Supplement No. 4

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-01-01

    On September 17, 1980, the Nuclear Regulatory Commission (NRC) issued the facility operating license DPR-77 to the Tennessee Valley Authority for the Sequoyah Nuclear Plant, Unit 1, located in Hamilton County, Tennessee. The license authorized operation of Unit 1 at 100 percent power; however, a license condition regarding the adequacy of the hydrogen control system was included that required resolution by January 31, 1981. The purpose of Supplement No. 4 to the SER is to further update our Safety Evaluation Reports on the hydrogen control measures (Section 22.2, II.B.7), and to comply with the license condition which is as follows: 'By January 31, 1981, TVA shall by testing and analysis show to the satisfaction of the NRC staff that an interim hydrogen control system will provide with reasonable assurance protection against breach of containment in the event that a substantial quantity of hydrogen is generated.' TVA submitted on December 11, 1980, the first quarterly report on the research program for hydrogen control. Also, TVA revised volume 2 of the Sequoyah Core Degradation Program Report to incorporate additional information on the overall program. Section II.B.7 of Supplement No. 4 responds to the license condition. Each section is supplementary to and not in lieu of discussion in the Safety Evaluation Report and Supplements Nos. 1, 2, and 3, except where specifically noted. Supplements No. 2 and 3 to the Safety Evaluation Report provided a basis for concluding that the full-power licensing of Sequoyah Unit 1 need not await completion of ongoing work on hydrogen control measures. This supplement concludes that operation of the IDIS for an interim period of one year is appropriate.

  9. Practical Recommendations on Supplemental Feeding Introduction

    Directory of Open Access Journals (Sweden)

    S. G. Makarova

    2015-01-01

    Full Text Available Despite the availability of a national consensus document describing in detail modern approaches to feeding infants, pediatricians keep on giving most diverse recommendations on the time of supplemental feeding introduction. The article presents a brief historical review, as well the modern view on the issue of introduction of supplemental feeding to children. In the previous century, it was common both in Russia and most European countries to introduce supplemental feeding to children at the age of 2 or even 1.5 months. In 2002, the World Health Organization put forward an initiative in support of breastfeeding and recommended not to introduce supplemental feeding before the age of 6 months. A certain “golden mean” has apparently been achieved on the basis of results of studies and a longterm discussion among the specialists in feeding from different countries — all scientific communities and national recommendations of most countries define the optimal age for supplemental feeding introduction as “from 4 (completed months to 6 (completed months” with certain individual approach. 

  10. Boron supplementation in broiler diets

    Directory of Open Access Journals (Sweden)

    EJ Fassani

    2004-12-01

    Full Text Available Boron supplementation in broiler feed is not a routine practice. However, some reports suggest a positive effect of boron on performance. This study assessed the effects of boron supplementation on broiler performance. Diets were based on maize and soybean meal, using boric acid P.A. as boron source. Six supplementation levels (0, 30, 60, 90, 120 and 150 ppm were evaluated using 1,440 one-day old males housed at a density of 30 chickens in each of 48 experimental plots of 3m². A completely randomized block design was used with 8 replicates. Feed intake, weight gain and feed conversion were assessed in the periods from 1 to 7 days, 1 to 21 days and 1 to 42 days of age, and viability was evaluated for the total 42-day rearing period. No performance variable was affected by boron supplementation (p>0.05 in the period from 1 to 7 days. The regression analysis indicated an ideal level of 37.4 ppm of boron for weight gain from 1 to 21 days (p0.05, although feed intake was reduced linearly with increased boron levels (p0.05. Ash and calcium percentages in the tibias of broilers and viability in the total rearing period were not affected by boron supplementation (p>0.05.

  11. 49 CFR 551.63 - May a foreign manufacturer submit a designation by email or facsimile?

    Science.gov (United States)

    2010-10-01

    ... email or facsimile? 551.63 Section 551.63 Transportation Other Regulations Relating to Transportation... foreign manufacturer submit a designation by email or facsimile? No, the statute requires designation... designation documents submitted via email or facsimile, as they do not satisfy this requirement. ...

  12. Characterization of inorganic compounds in nutritional supplements by the instrumental neutron activation analysis

    International Nuclear Information System (INIS)

    Nardi, Daniela T.; Saiki, Mitiko; Vasconcellos, Maria B.A.

    2000-01-01

    In this work instrumental neutron activation analysis was applied in the analyses of samples of nutritional supplements in order to evaluate the composition of their essential inorganic components. Results obtained in these analyses presented, in general, a good agreement with the label values. Precision and accuracy of the results were also evaluated by analyzing NIST 2704 Buffalo River Sediment and NIST 1400 Bone Ash reference materials. (author)

  13. Dietary supplement good manufacturing practices: preparing for compliance

    National Research Council Canada - National Science Library

    Mead, William J

    2012-01-01

    "Dietary Supplement GMP is a one-stop "how-to" road map to the final dietary supplement GMP regulations recently issued by the FDA covering the manufacture, packaging, and holding of dietary supplement...

  14. Wear resistance of AISI 304 stainless steel submitted to low temperature plasma carburizing

    Directory of Open Access Journals (Sweden)

    Marcos Antônio Barcelos

    Full Text Available Abstract Despite the AISI 304 stainless steel has high corrosion/oxidation resistance, its tribological properties are poor, being one of the barriers for use in severe wear applications. Thus, there is a wide field for studying technologies that aim to increase the surface hardness and wear resistance of this material. In this work, hardness and wear resistance for AISI 304 stainless steel submitted to the thermochemical treatment by low temperature plasma carburizing (LTPC in a fixed gas mixture composition of 93% H2 and 7% CH4 are presented. Through the evaluation of the carburizing layers, it was possible to observe a substantial improvement in tribological properties after all temperature and time of treatment. This improvement is directly related to the increase of the process variables; among them temperature has a stronger influence on the wear resistance obtained using LTPC process.

  15. Troubleshooting during Installing Ubuntu Enterprise Cloud Supplement (3) to “Guidelines for Building a Private Cloud Infrastructure"

    DEFF Research Database (Denmark)

    Panatic, Zoran; Ali Babar, Muhammad

    2012-01-01

    This document provides supplemental material to the book “Guidelines for building a private cloud infrastructure”. This document describes the issues that can be expected during the different phases of the setup and installation of Ubuntu Enterprise Cloud. This document also contains some useful...

  16. Comparison of a Medication Inventory and a Dietary Supplement Interview in Assessing Dietary Supplement Use in the Hispanic Community Health Study/Study of Latinos

    Directory of Open Access Journals (Sweden)

    Keturah R. Faurot

    2016-01-01

    Full Text Available Although dietary supplement use is common, its assessment is challenging, especially among ethnic minority populations such as Hispanics/Latinos. Using the Hispanic Community Health Study/Study of Latinos (HCHS/SOL (n = 16,415, this report compares two strategies for capturing dietary supplement use over a 30-day period: a medication-based inventory and a nutrition-based dietary supplement interview. Age-standardized prevalence was calculated across multiple dietary supplement definitions, adjusted with survey/nonresponse weights. The prevalence of dietary supplement use was substantially higher as measured in the dietary supplement interview, compared to the medication inventory: for total dietary supplements (39% vs 26%, respectively, for nonvitamin, nonmineral supplements (24% vs 12%, and for botanicals (9.2% vs 4.5%. Concordance between the two assessments was fair to moderate (Cohen's kappa: 0.31–0.52. Among women, inclusion of botanical teas increased the prevalence of botanical supplement use from 7% to 15%. Supplement assessment that includes queries about botanical teas yields more information about patient supplement use.

  17. Idaho supplementation studies : five year report : 1992-1996

    International Nuclear Information System (INIS)

    Walters, Jody P.; Idaho. Dept. of Fish and Game; United States. Bonneville Power Administration. Division of Fish and Wildlife.

    1999-01-01

    In 1991, the Idaho Supplementation Studies (ISS) project was implemented to address critical uncertainties associated with hatchery supplementation of chinook salmon Oncorhynchus tshawytscha populations in Idaho. The project was designed to address questions identified in the Supplementation Technical Work Group (STWG) Five-Year-Workplan (STWG 1988). Two goals of the project were identified: (1) assess the use of hatchery chinook salmon to increase natural populations in the Salmon and Clearwater river drainages, and (2) evaluate the genetic and ecological impacts of hatchery chinook salmon on naturally reproducing chinook salmon populations. Four objectives to achieve these goals were developed: (1) monitor and evaluate the effects of supplementation on presmolt and smolt numbers and spawning escapements of naturally produced fish; (2) monitor and evaluate changes in natural productivity and genetic composition of target and adjacent populations following supplementation; (3) determine which supplementation strategies (broodstock and release stage) provide the quickest and highest response in natural production without adverse effects on productivity; and (4) develop supplementation recommendations. This document reports on the first five years of the long-term portion of the ISS project. Small-scale studies addressing specific hypotheses of the mechanisms of supplementation effects (e.g., competition, dispersal, and behavior) have been completed. Baseline genetic data have also been collected. Because supplementation broodstock development was to occur during the first five years, little evaluation of supplementation is currently possible. Most supplementation adults did not start to return to study streams until 1997. The objectives of this report are to: (1) present baseline data on production and productivity indicators such as adult escapement, redd counts, parr densities, juvenile emigrant estimates, and juvenile survival to Lower Granite Dam (lower Snake

  18. 29 CFR 551.5 - Information to be submitted.

    Science.gov (United States)

    2010-07-01

    ... employees compensated under the plan, including information as to the types of goods delivered, their points... application of the plan which are relied upon to support a finding that the plan has the general purpose and... 29 Labor 3 2010-07-01 2010-07-01 false Information to be submitted. 551.5 Section 551.5 Labor...

  19. [Oral nutritional supplementation in hematologic patients].

    Science.gov (United States)

    Peñalva, A; San Martín, A; Rosselló, J; Pérez-Portabella, C; Palacios, A; Julià, A; Planas, M

    2009-01-01

    Hematological patients often present anorexia which along with other secondary effects from the chemotherapy and/or radiotherapy treatments compromise their nutritional status. Oral supplementation can aid to fulfill the energy and protein requirements of these patients. Nevertheless, the use of commercial nutritional supplements normally available, is limited by its poor intake. To evaluate the degree of fulfillment of the prescribed supplements and fulfillment of energy requirements, as well as the development of nutritional status in hematological patients hospitalized for treatment with chemotherapy and/or radiotherapy. Prospective, randomized and open study of inpatients at the hematological ward. Patients were randomized sequentially and they were assigned into 3 different nutritional interventions providing: Group 1 (G1), a flavored supplement; Group 2 (G2): a non flavored (neutral) supplement and Group 3 (G3): "kitchen" foods as supplements. Need and amount of nutritional supplements were provided according to the oral intake previously analyzed. Nutritional assessment (at admission and discharge) was based in the Subjective Global Assessment test (SGA), Risk Nutritional Index (RNI) and percentage of lost weight. Both fulfillment of supplement intake and achievement of energetic requirements were analyzed. 125 patients of 51.3 +/- 16.8 years; 45% men and 55% women. 54% lymphoma, 33% leukemia, 8% myeloma and others 4%. Length of stay (LOS): 7.0 +/- 3.6 d. The nutritional assessment done by SGA showed significant negative changes in G2 and G3 (G1: 30% developed malnutrition and 28% improved their nutritional status, p = NS; G2: 50% developed malnutrition against 7% whom improved their nutritional status, p = 0.002; y G3: 37% developed malnutrition against 21% whom improved their nutritional status, p = 0.02). According to RNI, patients evolved negatively from their nutritional state but no significant differences were found within groups (G1, from 81% of

  20. 30 CFR 285.601 - When am I required to submit my plans to MMS?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When am I required to submit my plans to MMS... Information Requirements § 285.601 When am I required to submit my plans to MMS? Your plan submission...) You must provide sufficient data and information with your COP for MMS to complete the needed reviews...

  1. The Effect of Different Doses of Vitamin D Supplementation on Insulin Resistance in ovariectomized rats

    Directory of Open Access Journals (Sweden)

    Rastegar Hoseini

    2016-04-01

    Full Text Available Background and Aim: Type 2 diabetes mellitus (T2DM and vitamin D deficiency are both too common during menopause. Since the effect of different doses of vitamin D supplements on blood sugar, insulin concentration  and insulin resistance are unknown, the present study aimed at investigating the effects of different doses of the vitamin D supplements on visceral fat, blood sugar, insulin concentration,  and insulin resistance in ovariectomized rats. Materials and Methods: In this randomized experimental study, 32 female Wistar rats were divided into 4 equal groups  as follows: three groups . that received vitamin D supplements (high, moderate, and low dose and one control group. After 8 weeks of different doses of vitamin D supplementation plasma concentration of glucose, insulin and HOMA-IR were measured  in the three groups. The obtained data  was statistically analyzed by means of dependent t-test and ANOVA . at the significance level of P<0.05. Results: After a period of eight-week  intervention, body weight, BMI, waist circumference, visceral fat, insulin, blood glucose and HOMA-IR at high, moderate, and low doses of vitamin D supplementation were significantly lower than those in the control group (P<0.05. High dose of vitamin D compared with moderate and low doses significantly caused reduction in insulin, blood glucose, and HOMA-IR (P<0.001 for all three variables. Conclusion: The findings of the current study showed that a high dose of vitamin D causes significant improvements in FPG, insulin, and insulin resistance  evaluated by HOMA-IR. It was also found that adding vitamin D supplements can improve glucose control in menopause model of rats.

  2. Assessment of the Authenticity of Herbal Dietary Supplements: Comparison of Chemical and DNA Barcoding Methods.

    Science.gov (United States)

    Pawar, Rahul S; Handy, Sara M; Cheng, Raymond; Shyong, Nicole; Grundel, Erich

    2017-07-01

    About 7 % of the U. S. population reports using botanical dietary supplements. Increased use of such supplements has led to discussions related to their authenticity and quality. Reports of adulteration with substandard materials or pharmaceuticals are of concern because such substitutions, whether inadvertent or deliberate, may reduce the efficacy of specific botanicals or lead to adverse events. Methods for verifying the identity of botanicals include macroscopic and microscopic examinations, chemical analysis, and DNA-based methods including DNA barcoding. Macroscopic and microscopic examinations may fail when a supplement consists of botanicals that have been processed beyond the ability to provide morphological characterizations. Chemical analysis of specific marker compounds encounters problems when these compounds are not distinct to a given species or when purified reference standards are not available. Recent investigations describing DNA barcoding analysis of botanical dietary supplements have raised concerns about the authenticity of the supplements themselves as well as the appropriateness of using DNA barcoding techniques with finished botanical products. We collected 112 market samples of frequently consumed botanical dietary supplements of ginkgo, soy, valerian, yohimbe, and St. John's wort and analyzed each for specific chemical markers (i.e., flavonol glycosides, total isoflavones, total valerenic acids, yohimbine, and hypericins, respectively). We used traditional DNA barcoding techniques targeting the nuclear ITS2 gene and the chloroplast gene psb A- trn H on the same samples to determine the presence of DNA of the labelled ingredient. We compared the results obtained by both methods to assess the contribution of each in determining the identity of the samples. Georg Thieme Verlag KG Stuttgart · New York.

  3. Antioxidant supplements and mortality

    DEFF Research Database (Denmark)

    Bjelakovic, Goran; Nikolova, Dimitrinka; Gluud, Christian

    2014-01-01

    Oxidative damage to cells and tissues is considered involved in the aging process and in the development of chronic diseases in humans, including cancer and cardiovascular diseases, the leading causes of death in high-income countries. This has stimulated interest in the preventive potential of a...... of antioxidant supplements. Today, more than one half of adults in high-income countries ingest antioxidant supplements hoping to improve their health, oppose unhealthy behaviors, and counteract the ravages of aging....

  4. Short-term energy outlook, annual supplement 1994

    International Nuclear Information System (INIS)

    1994-08-01

    The Short-Term Energy Outlook Annual Supplement (Supplement) is published once a year as a complement to the Short-Term Energy Outlook (Outlook), Quarterly Projections. The purpose of the Supplement is to review the accuracy of the forecasts published in the Outlook, make comparisons with other independent energy forecasts, and examine current energy topics that affect the forecasts

  5. Short-term energy outlook annual supplement, 1993

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-08-06

    The Short-Term Energy Outlook Annual Supplement (supplement) is published once a year as a complement to the Short-Term Energy Outlook (Outlook), Quarterly Projections. The purpose of the Supplement is to review the accuracy of the forecasts published in the Outlook, make comparisons with other independent energy forecasts, and examine current energy topics that affect the forecasts.

  6. Weight Loss Nutritional Supplements

    Science.gov (United States)

    Eckerson, Joan M.

    Obesity has reached what may be considered epidemic proportions in the United States, not only for adults but for children. Because of the medical implications and health care costs associated with obesity, as well as the negative social and psychological impacts, many individuals turn to nonprescription nutritional weight loss supplements hoping for a quick fix, and the weight loss industry has responded by offering a variety of products that generates billions of dollars each year in sales. Most nutritional weight loss supplements are purported to work by increasing energy expenditure, modulating carbohydrate or fat metabolism, increasing satiety, inducing diuresis, or blocking fat absorption. To review the literally hundreds of nutritional weight loss supplements available on the market today is well beyond the scope of this chapter. Therefore, several of the most commonly used supplements were selected for critical review, and practical recommendations are provided based on the findings of well controlled, randomized clinical trials that examined their efficacy. In most cases, the nutritional supplements reviewed either elicited no meaningful effect or resulted in changes in body weight and composition that are similar to what occurs through a restricted diet and exercise program. Although there is some evidence to suggest that herbal forms of ephedrine, such as ma huang, combined with caffeine or caffeine and aspirin (i.e., ECA stack) is effective for inducing moderate weight loss in overweight adults, because of the recent ban on ephedra manufacturers must now use ephedra-free ingredients, such as bitter orange, which do not appear to be as effective. The dietary fiber, glucomannan, also appears to hold some promise as a possible treatment for weight loss, but other related forms of dietary fiber, including guar gum and psyllium, are ineffective.

  7. Evaluation of ventriculography as a supplement to computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Nakstad, P.; Sortland, O.; Hovind, K.

    1982-04-01

    The diagnostic value of ventriculography (VGR) as a supplement to computed tomography (CT) is evaluated in 42 patients. CT was slightly superior for diagnosing expanding lesions and could tell more about the size and nature of the processes in this selected material which includes only lesions adjacent to the ventricular system. VGR yielded more information about the attachment of a tumor to the wall, floor, or roof of the ventricles. Stenosis or occlusion of the Sylvian aqueduct, communicating hydrocephalus, and basal adhesive arachnoiditis were diagnosed by VGR, while the correct diagnosis could be suggested only by CT in these cases.

  8. Prevalence of Bordetella pertussis and Bordetella parapertussis in Samples Submitted for RSV Screening

    Directory of Open Access Journals (Sweden)

    Walsh, Paul

    2008-08-01

    Full Text Available BACKGROUND: The clinical presentation of Bordetella pertussis can overlap with that of respiratory syncytial virus (RSV; however, management differs.HYPOTHESIS: First, the prevalence of B. pertussis is less than 2% among patients screened for RSV, and second the prevalence of B. parapertussis is also less than 2% among these patients.METHODS: Nasal washings submitted to a clinical laboratory for RSV screening were tested for B. pertussis and B. parapertussis, using species-specific real-time polymerase chain reaction (PCR assays. These were optimized to target conserved regions within a complement gene and the CarB gene, respectively. A Bordetella spp. genus-specific real-time PCR assay was designed to detect the Bhur gene of B. pertussis, B. parapertussis, and B. bronchiseptica. RSV A and B subtypes were tested by reverse transcription-PCR.RESULTS: Four hundred and eighty-nine clinical samples were tested. There was insufficient material to complete testing for one B. pertussis, 10 RSV subtype A, and four RSV subtype B assays. Bordetella pertussis was detected in 3/488 (0.6% (95% CI 0.1% to 1.8%, while B. parapertussis was detected in 5/489 (1.0% (95% CI 0.3% to 2.4%. Dual infection of B. pertussis with RSV and of B. parapertussis with RSV occurred in two and in three cases respectively. RSV was detected by PCR in 127 (26.5%.CONCLUSION: The prevalence of B. pertussis in nasal washings submitted for RSV screening was less than 2%. The prevalence of parapertussis may be higher than 2%. RSV with B. pertussis and RSV with B. parapertussis coinfection do occur.

  9. Effect of Eight Weeks Forced Swimming Training with Methadone Supplementation on Aspartate Aminotransferase, Alanine Aminotransferase, and Alkaline Phosphatase of Rats

    Directory of Open Access Journals (Sweden)

    Seyed Ali Hoseini

    2016-12-01

    Full Text Available Background & Objective: Narcotics abuse can induce liver disorders; nevertheless, exercises improve liver disorders. The present research aimed to review the effect of eight weeks forced swimming training with methadone supplementation on liver enzymes of rats. Material & Method: In this experimental research, 48 rats were selected, and after one week adaptation to lab environment, they were randomly divided into four groups of 12 rats including (1 forced swimming training, (2 methadone supplementation, (3 forced swimming training with methadone supplementation, and (4 control. Groups 2 and 3 used 2 mg/kg methadone daily for 8 weeks. Also, groups 1 and 3 swam for 8 weeks, three sessions per week and each session for 30 minutes. For statistical analysis of data, one way ANOVA and Tukey post hoc tests were used (α≤0.05. Results: Findings showed that forced swimming training, methadone supplementation, and forced swimming training with methadone supplementation had no significant effect on AST (P=0.90 and ALT (P=0.99 enzymes; forced swimming training had significant effect on increase of ALP (P=0.001; also, forced swimming training, compared with methadone supplementation and combination of forced swimming training with methadone supplementation, had significant effect on increase of ALP (P=0.001. Conclusion: Accordingly, 8 weeks of forced swimming training with methadone has possibly no significant effect on liver enzymes.

  10. Let's start learning radiation. Supplementary material on radiation for secondary school students

    International Nuclear Information System (INIS)

    Watanabe, Yoko; Yamashita, Kiyonobu; Shimada, Mayuka

    2015-01-01

    The Japan Atomic Energy Agency has been organizing training programs for engineers in Asian countries introducing nuclear technology. In 2012, we launched a course ‘Basic Radiation Knowledge for School Education’ as we thought disseminating accurate knowledge on radiation to school students and public would also be important in those countries after Fukushima-Daiichi nuclear power station accident. Ministry of Education, Culture, Sports, Science and Technology - Japan published supplemental learning material on radiation for secondary school students and teachers in Japanese in October 2011. Since the learning material is designed to give a clear explanation of radiation and covers various topics, we thought it would also be beneficial for young students in the world if a learning material in English was available. Therefore, we made a new learning material in English using the topics covered in supplemental learning material on radiation in Japanese as a reference. This learning material has been favourably evaluated by the International Atomic Energy Agency (IAEA) and will be widely used as a practical educational tool in many countries around the world through the IAEA. (author)

  11. Determination of selenium mineral in health supplement products: Applications of nuclear methods in pharmaceuticals fields

    International Nuclear Information System (INIS)

    Titiek Martati; Mellawati

    2010-01-01

    Recently, many health supplement products that are useful as an antioxidant available in the market, and one of them is selenium (Se) tablet. Issue on the falsification of drug due to control to health supplement product becomes very important. There is also some problem in Se analysis, especially in chemical reagent preparation. In this research, determination of Se in health supplement tablet using neutron activation analysis (NAA) was carried out. The advantages of methods are due to nondestructive materials, simple sample preparation, and no chemical reagent for analysis. The sample was irradiated using thermal neutron with 10"1"3 neutron cm"-"2 seconds"-"1 fluxes during 15 minutes, and based on n, γ reaction "7"5Se isotope would be formed that could identified using gamma spectrometer on 136, 264, and 279 keV energies. The result showed that NAA method can be used for Se analysis contained in health supplement tablets with accuracy ranged between 101.81 and 102.29 % and precision 99.02-99.37 %. The recovery test of Se mineral concentration to the labeled attached showed 105.79-116.66 %, and this value still in the range described in the United States Pharmacopoeias 28 (90-125 %). (author)

  12. Nutritional supplements

    DEFF Research Database (Denmark)

    Petersen, Gry Bjerg; Andersen, Jens Rikardt

    2015-01-01

    Background: Several studies have indicated that cancer patients have significantly altered taste sensitivity without specifying the preferences. One of the related problems is low compliance to nutritional therapy with oral nutritional supplements (ONS) in patients suffering severe weight loss...

  13. 48 CFR 852.236-88 - Contract changes-supplement.

    Science.gov (United States)

    2010-10-01

    ... small tools, incidental job burdens, and general home office expenses and no separate allowance will be... contractor shall submit proposals for changes in work to the resident engineer. Proposals, to be submitted as..., labor costs (separated into trades), construction equipment, etc. (Labor costs are to be identified with...

  14. Regional Assessment of Supplementation Project. Status report

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-01

    The Fish and Wildlife Program of the Northwest Power Planning Council (NPPC) prescribes several approaches to achieve its goal of doubling the salmon and steelhead runs of the Columbia River. Among those approaches are habitat restoration, improvements in adult and juvenile passage at dams and artificial propagation. Supplementation will be a major part of the new hatchery programs. The purpose of the Regional Assessment of Supplementation Project (RASP) is to provide an overview of ongoing and planned supplementation activities, to construct a conceptual framework and model for evaluating the potential benefits and risks of supplementation and to develop a plan for better regional coordination of research and monitoring and evaluation of supplementation. RASP has completed its first year of work. Progress toward meeting the first year`s objectives and recommendations for future tasks are contained in this report.

  15. DNA barcode authentication of saw palmetto herbal dietary supplements.

    Science.gov (United States)

    Little, Damon P; Jeanson, Marc L

    2013-12-17

    Herbal dietary supplements made from saw palmetto (Serenoa repens; Arecaceae) fruit are commonly consumed to ameliorate benign prostate hyperplasia. A novel DNA mini-barcode assay to accurately identify [specificity = 1.00 (95% confidence interval = 0.74-1.00); sensitivity = 1.00 (95% confidence interval = 0.66-1.00); n = 31] saw palmetto dietary supplements was designed from a DNA barcode reference library created for this purpose. The mini-barcodes were used to estimate the frequency of mislabeled saw palmetto herbal dietary supplements on the market in the United States of America. Of the 37 supplements examined, amplifiable DNA could be extracted from 34 (92%). Mini-barcode analysis of these supplements demonstrated that 29 (85%) contain saw palmetto and that 2 (6%) supplements contain related species that cannot be legally sold as herbal dietary supplements in the United States of America. The identity of 3 (9%) supplements could not be conclusively determined.

  16. Report of the Material Control and Material Accounting Task Force: summary

    International Nuclear Information System (INIS)

    1978-03-01

    A special review was made of the safeguards maintained by licensees possessing 5 kg or more of strategic special nuclear material (SSNM), i.e., plutonium, uranium-233, or uranium enriched in the uranium-235 isotope to 20 percent or more. A Task Force was formed to define the roles and objectives of material control and material accounting in the NRC safeguards program; recommend goals for material control and material accounting systems based on their roles and objectives; assess the extent to which the existing regulatory base meets or provides the capability to meet the recommended goals; and to provide direction for material control and material accounting development, including both near-term and long-term upgrades. Based on results of Task Force investigations it is recommended that licensee plans for measurement control programs be submitted in response to Section 70.57(c) of Title 10 of the Code of Federal Regulations. Other recommendations include the review and upgrading, as necessary, of measurement error propagation models used by each licensee; revision of Nuclear Materials Management and Safeguards System (NMMSS) reporting entities for SSNM licensees to be consistent with the partitioning of facilities into plants or, if appropriate, accounting units; review of NMMSS reporting entities for SSNM licensees to assure that data for high enriched uranium operations are clearly separated from low enriched uranium operations; upgrading of the editing by NMMSS of reported licensee safeguards data for accuracy and consistency; and the acquisition of (a) a secure interactive computer capability for use in collecting, storing, sorting, and analyzing special nuclear material accounting data, and (b) associated flexible computer software that presents safeguards information in a succinct and comprehensive manner

  17. Characteristics and analysis of scientific articles submitted to the European Annals of Otorhinolaryngology, Head and Neck Diseases.

    Science.gov (United States)

    Laccourreye, O; Bonfils, P; Denoyelle, F; Garrel, R; Jankowski, R; Karkas, A; Makeieff, M; Righini, C; Vincent, C; Martin, C

    2015-09-01

    To evaluate characteristics, suggested modifications and reasons for rejection in scientific articles submitted for publication in the European Annals of Otorhinolaryngology, Head and Neck Diseases. A prospective study analyzed the flaws noted by reviewers in 52 scientific articles submitted to the European Annals of Otorhinolaryngology, Head and Neck Diseases between August 31, 2014 and February 28, 2015. Fifteen flaws concerning content and 7 concerning form were identified. In more than 25% of submissions, major flaws were noted: purely descriptive paper; lack of contribution to existing state of knowledge; failure to define a clear study objective and/or analyze the impact of major variables; poorly structured Materials and methods section, lacking description of study population, objective and/or variables; lack of or inappropriate statistical analysis; Introduction verbose and/or misrepresenting the literature; excessively heterogeneous and/or poorly described study population; imprecise discussion, straying from the point, overstating the significance of results and/or introducing new results not mentioned in the Results section; description of the study population placed in the Results section instead of under Materials and methods; serious mistakes of syntax, spelling and/or tense; and failure to follow the Instructions to Authors. After review, 21.1% of articles were published, 65.3% rejected and 13.4% non-resubmitted within 3 months of review. On univariate analysis, the only variable increasing the percentage of articles accepted was the topic not being devoted to head and neck surgery (P=0.03). These results document the excessive flaw rate still to be found in manuscripts and demonstrate the continuing need for authors to master and implement the rules of scientific medical writing. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  18. Practical Issues in Evidence-Based Use of Performance Supplements: Supplement Interactions, Repeated Use and Individual Responses.

    Science.gov (United States)

    Burke, Louise M

    2017-03-01

    Current sports nutrition guidelines recommend that athletes only take supplements following an evidence-based analysis of their value in supporting training outcomes or competition performance in their specific event. While there is sound evidence to support the use of a few performance supplements under specific scenarios (creatine, beta-alanine, bicarbonate, caffeine, nitrate/beetroot juice and, perhaps, phosphate), there is a lack of information around several issues needed to guide the practical use of these products in competitive sport. First, there is limited knowledge around the strategy of combining the intake of several products in events in which performance benefits are seen with each product in isolation. The range in findings from studies involving combined use of different combinations of two supplements makes it difficult to derive a general conclusion, with both the limitations of individual studies and the type of sporting event to which the supplements are applied influencing the potential for additive, neutral or counteractive outcomes. The repeated use of the same supplement in sports involving two or more events within a 24-h period is of additional interest, but has received even less attention. Finally, the potential for individual athletes to respond differently, in direction and magnitude, to the use of a supplement seems real, but is hard to distinguish from normal day to day variability in performance. Strategies that can be used in research or practice to identify whether individual differences are robust include repeat trials, and the collection of data on physiological or genetic mechanisms underpinning outcomes.

  19. BJR supplements and radiotherapy treatment planning data - a review

    International Nuclear Information System (INIS)

    Agrawal, M.S.

    2000-01-01

    Scientific community has depended on the BJR Supplements on central axis depth dose data published from time to time. There have been five supplements since 1953 when Supplement No. 5 was first published on the subject. The frequent revisions, addition of new data and updating with the technological advancements are special features of these supplements. The most recent supplement is numbered 25 and has been brought out in 1996. A review of the data in respect of cobalt-60, MV X-rays and electron beams as described in the supplements is the subject matter of this write-up. (author)

  20. Photosynthetically supplemental lighting for vegetable crop production with super-bright laser diode

    Science.gov (United States)

    Hu, Yongguang; Li, Pingping; Shi, Jintong

    2007-02-01

    Although many artificial light sources like high-pressure sodium lamp, metal halide lamp, fluorescent lamp and so on are commonly used in horticulture, they are not widely applied because of the disadvantages of unreasonable spectra, high cost and complex control. Recently new light sources of light-emitting diode (LED) and laser diode (LD) are becoming more and more popular in the field of display and illumination with the improvement of material and manufacturing, long life-span and increasingly low cost. A new type of super-bright red LD (BL650, central wavelength is 650 nm) was selected to make up of the supplemental lighting panel, on which LDs were distributed with regular hexagon array. Drive circuit was designed to power it and adjust light intensity. System performance including temperature rise and light intensity distribution under different vertical/horizontal distances were tested. Photosynthesis of sweet pepper and eggplant leaf under LD was measured with LI-6400 to show the supplemental lighting effects. The results show that LD system can supply the maximum light intensity of 180 μmol/m2 •s at the distance of 50 mm below the panel and the temperature rise is little within 1 °C. Net photosynthetic rate became faster when LD system increased light intensity. Compared with sunlight and LED supplemental lighting system, LD's promotion on photosynthesis is in the middle. Thus it is feasible for LD light source to supplement light for vegetable crops. Further study would focus on the integration of LD and other artificial light sources.

  1. Prevalence of Dietary Supplements Use among Gymnasium Users

    Directory of Open Access Journals (Sweden)

    Ayman H. Jawadi

    2017-01-01

    Full Text Available Background. Several studies showed that regular gymnasium users use various dietary supplements without comprehension of their potential risks. Objective. To determine the prevalence and dietary supplement intake and assess the awareness of supplement use among regular gymnasium users in Riyadh, Saudi Arabia. Methods. A descriptive cross-sectional study was conducted among regular gymnasium users in Riyadh, Saudi Arabia, between April 2015 and June 2015. A validated structured questionnaire was used. Results. The study included 299 participants. Of these 113 (37.8% were dietary supplements users and this was more common among males than females (44.7% versus 16.4%. Gender based analysis showed that males were exercising more frequently than females and the type of cardiovascular exercise was more among them. The most commonly used supplements were whey protein (22.1%, amino acids (16.8%, multivitamins (16.8%, creatine (11.5%, and omega 3 (11.5%. The reasons for taking dietary supplements were to improve body shape (47.7%, increase health (44.2%, and improve performance (41.5%. Conclusion. Most of the information about supplements was obtained from unreliable sources. More studies are needed to better understand supplements use and their impact on health in Saudi Arabia.

  2. Calcium supplementation and cardiovascular risk: A rising concern.

    Science.gov (United States)

    Tankeu, Aurel T; Ndip Agbor, Valirie; Noubiap, Jean Jacques

    2017-06-01

    Over the past decade, the number of individuals taking calcium supplementation worldwide has been on the rise, especially with the emergence of new pharmaceutical companies specialized in the marketing of dietary supplements; with calcium supplementation being their main business axis. This is mostly because of the established role of calcium in the prevention and treatment of osteoporosis and, to a lesser extent, its role in the prevention of fractures. Recently, a rising body of evidence on the adverse effect of calcium supplementation on nonskeletal, especially cardiovascular, health has been a cause for concern. In fact, a significant number of studies have reported an association between calcium supplementation and adverse cardiovascular events, even though high dietary calcium intake was shown to have a protective effect. The mechanism by which calcium supplementation could cause a cardiovascular event was still unclear until a recent study published in the Journal of the American Heart Association. Combining this recent finding with available data associating calcium supplementation with cardiovascular mortality and all-cause mortality, we call on the need for an evidence-based approach to calcium supplementation, while stressing on the safety of dietary calcium intake over the former on cardiovascular health. ©2017 Wiley Periodicals, Inc.

  3. Should states and local governments regulate dietary supplements?

    Science.gov (United States)

    Starr, Ranjani

    2016-01-01

    Federal regulation of dietary supplements in the United States is governed by the Dietary Supplement Health and Education Act of 1994. The law has been criticized as weak and ineffective. Alarming research has emerged demonstrating that supplements may be mislabelled, contaminated, adulterated with dangerous or unknown compounds, or sold at toxic doses. As a result, the health community has raised concerns about the safety and quality of dietary supplements. Increased federal oversight is an important avenue for improving supplement safety; however, states and local governments may also pursue strategies to strengthen the overall regulatory control of dietary supplements. States and local governments have substantial experience in regulating other products that pose a risk to public health, such as tobacco. Additionally, much has been learned about the tactics the tobacco industry has employed to protect its interests. Lessons learned may be applied to new regulatory efforts aimed at improving the safety of dietary supplements at the state and local levels. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  4. 14 CFR 193.5 - How may I submit safety or security information and have it protected from disclosure?

    Science.gov (United States)

    2010-01-01

    ... SUBMITTED INFORMATION § 193.5 How may I submit safety or security information and have it protected from... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false How may I submit safety or security information and have it protected from disclosure? 193.5 Section 193.5 Aeronautics and Space FEDERAL AVIATION...

  5. Supply and consumption of cardiovascular food supplements in lithuania

    OpenAIRE

    Liubartaitė, Elvyra

    2017-01-01

    Supply and Consumption of Cardiovascular Food Supplements in Lithuania. The aim - to evaluate supply and consumption of cardiovascular food supplements in Lithuania. Work tasks: • To collect information on food supplements for heart health. • To rate the range of food supplements for heart health sold in Lithuania. • To analyze the consumption of food supplements for heart health. Research data were collected through questionnaire data collection method based on January-February, 2017 data. 4...

  6. Over the counter drugs (and dietary supplement) exercise: a team-based introduction to biochemistry for health professional students.

    Science.gov (United States)

    Phadtare, Sangita; Abali, Emine; Brodsky, Barbara

    2013-01-01

    For successful delivery of basic science topics for health-professional students, it is critical to reduce apprehension and illustrate relevance to clinical settings and everyday life. At the beginning of the Biochemistry course for Physician Assistants, a team-based assignment was designed to develop an understanding of the mechanism of action, effectiveness, and toxicity of five common over the counter (OTC) drugs and dietary supplements, and place these familiar medicines in a political and historical context. The objectives of this exercise were to stimulate interest in biochemistry; to provide basic information on enzymes and enzyme inhibitors related to these drugs to be expanded upon later in the course; and to encourage active and interactive learning. Teams of five students were formed, and each student was given an information sheet on aspirin, alpha-galactosidase, orlistat, dextromethorphan, or simvastatin, a low dose statin, which was previously available without prescription at pharmacies in the UK. After each member of the team acquired information on one OTC drug/dietary supplement by reading an assigned information sheet, the team was asked to go through a series of questions, and then submit answers to a quiz as a group. A high rate of success on the quiz, an overwhelmingly positive response on formal course evaluations, and enthusiastic exchanges during class suggested this team-based session accomplished its goals. Copyright © 2013 Wiley-Liss, Inc.

  7. China: Past and Present. A Supplemental Activity Unit on Chinese Culture for Grades 7-12.

    Science.gov (United States)

    Parisi, Lynn

    Designed as a supplement to the classroom text, this unit contains 14 lessons on Chinese culture and society. Students are encouraged to compare the cultures of traditional and modern China as well as those of China and the United States. Materials are divided into two sections. The first section contains lesson outlines, including teaching plans,…

  8. How to submit an ATIP request | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Corporations, businesses, and organizations with a Canadian presence have the right to make an access to Information request. Please note that an applicant may be charged additional search fees and/or preparation fees in regards to a request they have submitted under the Access to Information Act.

  9. 15 CFR 711.5 - Numerical precision of submitted data.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Numerical precision of submitted data. 711.5 Section 711.5 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

  10. Composition variability in soy-derived dietary supplements designated for menopausal symptom prevention

    Directory of Open Access Journals (Sweden)

    Hubert Jane

    2006-09-01

    when the conjugation profiles were taken into account, as both heat and pH can selectively affect isoflavone and soyasaponin conjugation. Analyzing different lots revealed the importance of raw material and process cumulated variabilities: total isoflavones displayed large decreases (30% or increases (17%, and soyasaponin contents varied from 80% decrease to 30% increase. The characterization of the complex phytochemical mixture of a natural dietary supplement needs to be clarified since some active compounds may be responsible for additive, synergistic or antagonist effects only attributed to isoflavones. At least, given its influence on the end product composition, the information about the raw material origin (germ or whole seed is of great interest.

  11. Calcium supplementation in osteoporosis: useful or harmful?

    Science.gov (United States)

    Chiodini, Iacopo; Bolland, Mark J

    2018-04-01

    Osteoporosis and fragility fractures are important social and economic problems worldwide and are due to both the loss of bone mineral density and sarcopenia. Indeed, fragility fractures are associated with increased disability, morbidity and mortality. It is known that a normal calcium balance together with a normal vitamin D status is important for maintaining well-balanced bone metabolism, and for many years, calcium and vitamin D have been considered crucial in the prevention and treatment of osteoporosis. However, recently, the usefulness of calcium supplementation (alone or with concomitant vitamin D) has been questioned, since some studies reported only weak efficacy of these supplementations in reducing fragility fracture risk. On the other hand, besides the gastrointestinal side effects of calcium supplements and the risk of kidney stones related to use of co-administered calcium and vitamin D supplements, other recent data suggested potential adverse cardiovascular effects from calcium supplementation. This debate article is focused on the evidence regarding both the possible usefulness for bone health and the potential harmful effects of calcium and/or calcium with vitamin D supplementation. © 2018 European Society of Endocrinology.

  12. Impact of carbonation on water transport properties of cementitious materials

    International Nuclear Information System (INIS)

    Auroy, Martin

    2014-01-01

    Carbonation is a very well-known cementitious materials pathology. It is the major cause of reinforced concrete structures degradation. It leads to rebar corrosion and consequent concrete cover cracking. In the framework of radioactive waste management, cement-based materials used as building materials for structures or containers would be simultaneously submitted to drying and atmospheric carbonation. Although scientific literature regarding carbonating is vast, it is clearly lacking information about the influence of carbonation on water transport properties. This work then aimed at studying and understanding the change in water transport properties induced by carbonation. Simultaneously, the representativeness of accelerated carbonation (in the laboratory) was also studied. (author) [fr

  13. Effect of dietary supplementation of probiotics and enzymes on the haematology of rabbits reared under two housing systems

    Directory of Open Access Journals (Sweden)

    Sarat Chandra Amaravadhi

    Full Text Available Aim : To study the influence of housing system and dietary supplementation of probiotics and enzymes on haematological parameters of rabbits. Materials and Methods: A total of 144 weaned rabbits were divided into 2 groups of 72 in each group and housed under conventional cage system and backyard system. The rabbits in each housing system were divided into 4 groups of 18 in each group and the diets were supplemented with probiotics, enzymes and both. Results: The housing system and supplementation of probiotics and enzymes did not exert significant influence on any of the haematological parameters studied. However, there was slight positive influence of probiotic and enzyme supplementation on the health status of rabbits as revealed by haematological parameters. The overall mean Total erythrocyte count, total leucocyte count, lymphocytes, neutrophils, eosinophils, monocytes, haemoglobin and packed cell volume were 7.52, 6.29 (103/mm3, 60.27%, 35.71%, 1.35%, 1.92%, 10.67 g/dl and 34.25%, respectively. Conclusion: Rabbits can be reared on low input backyard system without any adverse effect on health and supplementation of probiotics and enzymes had a positive influence on health status of rabbits. [Vet World 2012; 5(12.000: 748-753

  14. Antioxidant supplements for preventing gastrointestinal cancers

    DEFF Research Database (Denmark)

    Bjelakovic, G; Nikolova, D; Simonetti, R G

    2004-01-01

    Oxidative stress may cause gastrointestinal cancers. The evidence on whether antioxidant supplements are effective in preventing gastrointestinal cancers is contradictory.......Oxidative stress may cause gastrointestinal cancers. The evidence on whether antioxidant supplements are effective in preventing gastrointestinal cancers is contradictory....

  15. Fitness in paradise: quality of forensic reports submitted to the Hawaii judiciary.

    Science.gov (United States)

    Robinson, Richard; Acklin, Marvin W

    2010-01-01

    This paper examined quality of forensic reports submitted to the Hawaii Judiciary. Hawaii utilizes a three panel system for assessing fitness to proceed, where two psychologists and one psychiatrist submit independent reports to the Court. Utilizing a survey instrument based on previous research and nationally-derived quality standards, 150 competency to stand trial (CST) reports were examined. Reports demonstrated pervasive mediocrity with respect to quality (Mean QC=68.95, SD=15.21). One quarter (N=38) of the reports scored at or above 80% of the maximum possible score. Levels of CST agreement between evaluators and evaluators and judges were high. Report quality did not differ as a function of evaluator professional identity. Full-time employed evaluators submitted a greater number of reports above the quality criterion. For those evaluators who attended the March training, reports demonstrated significantly improved quality. Suggestions for enhancing report quality are offered with a special attention to inclusion of report elements, focus on inclusion of historical elements, and clearly described rationales supporting forensic opinions. (7664 words. Competency to stand trial, inter-rater agreement).

  16. News from the Library: Share your work, submit your thesis to CDS!

    CERN Multimedia

    CERN Library

    2011-01-01

    Are you a student paid by CERN, using CERN equipment or advised by CERN staff and you are currently writing a thesis? Then you should know that you are welcome to submit your final work to the CERN Document Server (CDS), where it will be made available by Open Access.   This is the most efficient way of sharing your work within the community - your thesis will certainly find a much greater audience than if you follow the advice of certain dubious publishing companies (see the article Free access to science... but at what cost? published in this issue). At the same time, you ensure long-term storage of your file. All theses qualify, from bachelor to PhD, and any language is accepted. You simply go to CDS and submit your work. If your thesis was written some years ago it is still not too late to submit it; it will then get a new life on CDS! More information here. CERN Theses collection here. If you have any questions or submission problems, please do not hesitate to contact Catherine Cart. ...

  17. 78 FR 72099 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

    Science.gov (United States)

    2013-12-02

    ... January 2, 2014 for the assurance of consideration. ADDRESSES: Submit comments to the Office of... submitted is subject to subsequent audit and adjustment. A. Federal Oil and Gas Valuation Regulations The... allow or not allow one or both of the relief options . . . (d) If a State decides in advance . . . that...

  18. Feasibility and efficacy of progressive resistance training and dietary supplements in radiotherapy treated head and neck cancer patients - the DAHANCA 25A study

    DEFF Research Database (Denmark)

    Lønbro, Simon; Dalgas, Ulrik; Primdahl, Hanne

    2013-01-01

    weeks of PRT ± protein and creatine supplementation among HNSCC patients. Secondly, to investigate group changes over time and group differences regarding lean body mass (LBM), muscle strength and functional performance following PRT ± dietary supplementation. Material and methods. Thirty patients were...... supplementation. Before the pre-trial and pre- and post-PRT evaluation of LBM, maximal isometric and isokinetic muscle strength and functional performance were performed. Results. Seventy percent of the patients completed the intervention and the PRT adherence rate was 97%. No significant group differences were...... found in any endpoints. From pre- to post-PRT, LBM increased significantly in the PROCR group by 2.6 ± 2.2 kg (p

  19. Supplementation with bypass fat in silvopastoral systems diminishes the ratio of milk saturated/unsaturated fatty acids.

    Science.gov (United States)

    Mahecha, L; Angulo, J; Salazar, B; Cerón, M; Gallo, J; Molina, C H; Molina, E J; Suárez, J F; Lopera, J J; Olivera, M

    2008-04-01

    This study was conducted to evaluate if supplementing bypass fat to cows under silvopastoral systems, increases the concentration of unsaturated fatty acids in milk, thus improving the saturated/ unsaturated ratio without a negative effect on total milk yield in fat or protein. Two concentrations of two different sources of bypass fat were evaluated for 40 days, each in a group of 24 multiparous Lucerna (Colombian breed) cows. A cross-over design of 8 Latin squares 3 x 3 was used. The variables submitted to analysis were body condition, daily milk production and milk composition. Body condition, milk yield and milk quality were not different but there was a significant decrease in the amount of saturated fatty acid in both experiments while the unsaturated fat increased significantly in experiment 1 and remained stable in experiment 2. Results, such as these have as far as we know, not been reported previously and they provide an approach for the improvement of milk as a "functional food".

  20. Effects of 12-weeks physical activity and omega-3 supplementation on serum ghrelin and insulin levels in young women

    Directory of Open Access Journals (Sweden)

    Eskandar Rahimi

    2014-05-01

    Full Text Available Background: Normal levels of ghrelin and insulin hormones play an important role in energy-balance, weight control and preventing type 2 diabetes. The purpose of this study was to evaluate the effects of twelve weeks physical activity with omega-3 supplementation consumption on insulin and ghrelin hormones in young women. Materials and methods: In this semi-experimental study 60 young women aged 19-25 years randomly divided into four groups including. (Exercise with supplementation, exercise alone, supplementation alone and control group. Exercise group and exercise- supplementation group followed the basketball training for 12 weeks under the supervision of skillful trainers. Supplementation group and exercise- supplementation group were asked to take 3gram omega-3 capsules per day for 12 weeks. Anthropometric indicators and blood samples were obtained in the morning after an 8-12 hr fast prior to the start of the study and again 12weeks after at the end of the study under the same conditions to measure plasma ghrelin and insulin hormones (Elisa method. Data analysis using tests of Kolmogorov-Smirnov t-test, one-way analysis of variance (ANOVA conducted through SPSS-16 software. Results: The results of ANOVA test showed that after 12 weeks of study ghrelin and insulin levels in exercise-supplement group, (P=0.000, P=0.000, exercise group (P=0.000, P=0.000, and supplement group (P=0.044, P=0.017 significantly increase and decrease respectively. But no significant changes were observed in control group for ghrelin (P=0.740 and insulin (P= 0.108 levels before and after the study. Conclusion: Based on the results of this study, physical activity with omega-3 supplementation can create significant changes on the levels of ghrelin and insulin hormones in young women. These changes may help to control and prevent diabetes and its, complications.

  1. Supplementation in the Columbia Basin : Summary Report Series : Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-12-01

    This progress report broadly defines the scope of supplementation plans and activities in the Columbia Basin. It provides the foundation for more detailed analysis of supplementation in subsequent reports in this series. Topics included in this report are: definition of supplementation, project diversity, objectives and performance standards, uncertainties and theory. Since this is a progress report, the content is subject to modification with new information. The supplementation theory will continue to evolve throughout the duration of RASP and beyond. The other topics in this report are essentially complete and are not expected to change significantly. This is the first of a series of four reports which will summarize information contained in the larger, RASP progress and completion reports. Our goal is to make the findings of RASP more accessible by grouping related topics into smaller but complete narratives on important aspects of supplementation. We are planning to publish the following reports under the general title Supplementation in the Columbia River Basin: Part 1, Background, Description, Performance Measures, Uncertainty and Theory; Part 2, Theoretical Framework and Models; Part 3, Planning Guidelines; and Part 4, Regional Coordination of Research and Monitoring. Supplementation is expected to be a major contributor to the planned increase in salmon and steelhead production in the Columbia Basin. The Fish and Wildlife Program of the Northwest Power Planning Council (NPPC) uses three approaches to protect and enhance salmon and steelhead in the Columbia Basin: (1) enhance fish production; (2) improve passage in the mainstem rivers; and (3) revise harvest management to support the rebuilding of fish runs (NPPC 1987). The fish production segment calls for a three-part approach focused on natural production, hatchery production, and supplementation. Supplementation is planned to provide over half of the total production increases. The Regional Assessment

  2. 75 FR 29513 - Developing a Supplemental Poverty Measure

    Science.gov (United States)

    2010-05-26

    ... Supplemental Poverty Measure AGENCY: Bureau of the Census, Department of Commerce. ACTION: Notice and... comments on the approach to developing a Supplemental Poverty Measure (SPM) presented in a report entitled ``Observations from the Interagency Technical Working Group on Developing a Supplemental Poverty Measure,'' which...

  3. The prevalence of vitamin supplementation in ultraendurance triathletes.

    Science.gov (United States)

    Knez, Wade L; Peake, Jonathan M

    2010-12-01

    Ultraendurance exercise training places large energy demands on athletes and causes a high turnover of vitamins through sweat losses, metabolism, and the musculoskeletal repair process. Ultraendurance athletes may not consume sufficient quantities or quality of food in their diet to meet these needs. Consequently, they may use oral vitamin and mineral supplements to maintain their health and performance. We assessed the vitamin and mineral intake of ultraendurance athletes in their regular diet, in addition to oral vitamin and mineral supplements. Thirty-seven ultraendurance triathletes (24 men and 13 women) completed a 7-day nutrition diary including a questionnaire to determine nutrition adequacy and supplement intake. Compared with dietary reference intakes for the general population, both male and female triathletes met or exceeded all except for vitamin D. In addition, female athletes consumed slightly less than the recommended daily intake for folate and potassium; however, the difference was trivial. Over 60% of the athletes reported using vitamin supplements, of which vitamin C (97.5%), vitamin E (78.3%), and multivitamins (52.2%) were the most commonly used supplements. Almost half (47.8%) the athletes who used supplements did so to prevent or reduce cold symptoms. Only 1 athlete used supplements on formal medical advice. Vitamin C and E supplementation was common in ultraendurance triathletes, despite no evidence of dietary deficiency in these 2 vitamins.

  4. Should infant girls receive micronutrient supplements?

    DEFF Research Database (Denmark)

    Benn, Christine Stabell; Lund, Sofia; Fisker, Ane

    2009-01-01

    BACKGROUND: We have proposed the hypothesis that the combination of vitamin A supplementation and diphtheria-tetanus-pertussis (DTP) vaccination may be associated with increased mortality in girls. Recent zinc/folic acid (FA) and iron supplementation trials did not find any beneficial effects...

  5. International Congress on Energy Efficiency and Energy Related Materials

    CERN Document Server

    Bahsi, Zehra; Ozer, Mehmet; ENEFM2013

    2014-01-01

    The International Congress on Energy Efficiency and Energy Related Materials (ENEFM2013) was held on 9-12 October, 2013. This three-day congress focused on the latest developments of sustainable energy technologies, materials for sustainable energy applications and environmental & economic perspectives of energy. These proceedings include 63 peer reviewed technical papers, submitted from leading academic and research institutions from over 23 countries, representing some of the most cutting edge research available. The papers included were presented at the congress in the following sessions: General Issues Wind Energy Solar Energy Nuclear Energy Biofuels and Bioenergy Energy Storage Energy Conservation and Efficiency Energy in Buildings   Economical and Environmental Issues Environment Energy Requirements Economic Development   Materials for Sustainable Energy Hydrogen Production and Storage Photovoltaic Cells Thermionic Converters Batteries and Superconductors Phase Change Materials Fuel Cells Supercon...

  6. JOURNAL CLUB: Plagiarism in Manuscripts Submitted to the AJR: Development of an Optimal Screening Algorithm and Management Pathways.

    Science.gov (United States)

    Taylor, Donna B

    2017-04-01

    The objective of this study was to investigate the incidence of plagiarism in a sample of manuscripts submitted to the AJR using CrossCheck, develop an algorithm to identify significant plagiarism, and formulate management pathways. A sample of 110 of 1610 (6.8%) manuscripts submitted to AJR in 2014 in the categories of Original Research or Review were analyzed using CrossCheck and manual assessment. The overall similarity index (OSI), highest similarity score from a single source, whether duplication was from single or multiple origins, journal section, and presence or absence of referencing the source were recorded. The criteria outlined by the International Committee of Medical Journal Editors were the reference standard for identifying manuscripts containing plagiarism. Statistical analysis was used to develop a screening algorithm to maximize sensitivity and specificity for the detection of plagiarism. Criteria for defining the severity of plagiarism and management pathways based on the severity of the plagiarism were determined. Twelve manuscripts (10.9%) contained plagiarism. Nine had an OSI excluding quotations and references of less than 20%. In seven, the highest similarity score from a single source was less than 10%. The highest similarity score from a single source was the work of the same author or authors in nine. Common sections for duplication were the Materials and Methods, Discussion, and abstract. Referencing the original source was lacking in 11. Plagiarism was undetected at submission in five of these 12 articles; two had been accepted for publication. The most effective screening algorithm was to average the OSI including quotations and references and the highest similarity score from a single source and to submit manuscripts with an average value of more than 12% for further review. The current methods for detecting plagiarism are suboptimal. A new screening algorithm is proposed.

  7. Tyrosine supplementation for phenylketonuria.

    Science.gov (United States)

    Webster, Diana; Wildgoose, Joanne

    2013-06-05

    Phenylketonuria is an inherited disease for which the main treatment is the dietary restriction of the amino acid phenylalanine. The diet has to be initiated in the neonatal period to prevent or reduce mental handicap. However, the diet is very restrictive and unpalatable and can be difficult to follow. A deficiency of the amino acid tyrosine has been suggested as a cause of some of the neuropsychological problems exhibited in phenylketonuria. Therefore, this review aims to assess the efficacy of tyrosine supplementation for phenylketonuria. To assess the effects of tyrosine supplementation alongside or instead of a phenylalanine-restricted diet for people with phenylketonuria, who commenced on diet at diagnosis and either continued on the diet or relaxed the diet later in life. To assess the evidence that tyrosine supplementation alongside, or instead of a phenylalanine-restricted diet improves intelligence, neuropsychological performance, growth and nutritional status, mortality rate and quality of life. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Trials Register which is comprised of references identified from comprehensive electronic database searches, handsearches of relevant journals and abstract books of conference proceedings. Additional studies were identified from handsearches of the Journal of Inherited Metabolic Disease (from inception in 1978 to 1998). The manufacturers of prescribable dietary products used in the treatment of phenylketonuria were also contacted for further references.Date of the most recent search of the Group's Inborn Errors of Metabolism Trials Register: 28 June 2012. All randomised or quasi-randomised trials investigating the use of tyrosine supplementation versus placebo in people with phenylketonuria in addition to, or instead of, a phenylalanine-restricted diet. People treated for maternal phenylketonuria were excluded. Two authors independently assessed the trial eligibility, methodological quality

  8. An in vitro investigation of human enamel wear by restorative dental materials

    International Nuclear Information System (INIS)

    Adachi, L.K.; Saiki, M.; De Campos, T.N.

    2001-01-01

    A radiometric method was applied to asses enamel wear by another enamel and by restorative materials. The radioactive enamel was submitted to wear in a machine which allows sliding motion of an antagonistic surface in contact with the radioactive enamel. The enamel wear was evaluated by measuring the beta-activity of 32 P transferred to water from this irradiated tooth. Results obtained indicated that dental porcelains cause pronounced enamel wear when compared with that provoked by another natural enamel or by resin materials. Resin materials caused less enamel wear than another natural enamel. Vickers microhardness data obtained for antagonistic materials showed a correlation with the wear caused to the enamel. (author)

  9. Chemical and thermal analysis for characterisation of building materials

    International Nuclear Information System (INIS)

    Kumar, S.C.; Sudersanan, M.; Ravindran, P.V.; Kalekar, B.B.; Mathur, P.K.

    2000-01-01

    Cement and other construction materials are extensively used for the construction of shielding materials for nuclear and high energy radiations. The design and optimum utilisation of such materials need an accurate analysis of their chemical composition. The moisture content and presence of bound water and other volatile materials are also important. The use of thermal analysis supplements the data obtained by chemical analysis and enables a distinction of moisture and chemically bound water. It also enables an identification of the process leading to the loss on ignition. The work carried out on the analysis of sand, cement and other aggregate materials used for the preparation of concrete is described in the paper. (author)

  10. Vitamin and mineral supplements: Do we really need them?

    Directory of Open Access Journals (Sweden)

    Farin Kamangar

    2012-01-01

    Full Text Available In the United States, 40 - 50% of the men and women 50 years of age or older regularly use multivitamin/mineral (MVM supplements, making the annual sales of these supplements over $11 billion. However, the question remains whether using MVM supplements is beneficial to health. This article reviews the results of randomized studies of MVM supplements and individual vitamins/mineral supplements in relation to overall mortality and incidence of chronic diseases, particularly cancer and ischemic heart disease. The results of large-scale randomized trials show that, for the majority of the population, there is no overall benefit from taking MVM supplements. Indeed, some studies have shown increased risk of cancers in relation to using certain vitamins.

  11. 76 FR 67729 - Information Collection Being Submitted for Review and Approval to the Office of Management and...

    Science.gov (United States)

    2011-11-02

    ... operators submit this form to local franchising authorities or the Commission, in situations where the FCC... changes in external costs. Cable operators submit FCC Form 1240 to their respective local franchising...

  12. An evidence-based elective on dietary supplements.

    Science.gov (United States)

    Bonafede, Machaon; Caron, Whitney; Zeolla, Mario

    2009-08-28

    To implement and evaluate the effectiveness of a pharmacy elective on dietary supplements that emphasized evidence-based care. A 3-credit elective that employed both traditional lectures and a variety of active-learning exercises was implemented. The course introduction provided a background in dietary supplement use and evidence-based medicine principles before addressing dietary supplements by primary indication. Student learning was assessed through quizzes, case assignments, discussion board participation, and completion of a longitudinal group project. Precourse and postcourse surveys were conducted to assess students' opinions, knowledge, and skills related to course objectives. The course was an effective way to increase students' knowledge of dietary supplements and skills and confidence in providing patient care in this area.

  13. Study of surface alterations of composite and ionomeric materials submitted to simulation of a high cariogenic challenge Estudo da erosão superficial de materiais compósitos e inoméricos submetidos à simulação de um alto desafio cariogênico

    Directory of Open Access Journals (Sweden)

    Alexandre Rezende VIEIRA

    1999-12-01

    Full Text Available We evaluated the surface of composite resins and glass-ionomer cements in a situation of high cariogenic challenge. Based on seventy-five standard test specimens of one glass-ionomer cement (Chelon Fil - ESPE, one resin-modified glass-ionomer (Vitremer - 3M, two polyacid-modified composite (VariGlass and Dyract - Dentsply and one composite resin (Heliomolar - Vivadent, submitted to fourteen days of demineralization and remineralization cycling to simulate a high cariogenic challenge, the erosive aspects of the surface of the materials were assessed. All of the samples were evaluated by scanning electronic microscope and compared with another five test specimens of each material, prepared in the same way and serving as control. All of the materials studied suffered erosive action by the media, with different characteristics due to the different compositions, after being submitted to in vitro simulation of a high cariogenic challenge.O objetivo deste trabalho foi avaliar a superfície de compósitos e cimentos de ionômero de vidro, frente a uma situação de alto desafio cariogênico. A partir de setenta e cinco corpos-de-prova padronizados de um cimento de ionômero de vidro (Chelon Fil - ESPE, um ionômero de vidro resina-modificado (Vitremer - 3M, dois compósitos poliácido-modificados (VariGlass e Dyract - Dentsply e um compósito (Heliomolar - Vivadent, e após serem submetidos a quatorze dias a ciclagens de desmineralização e remineralização, para simular um alto desafio cariogênico, foram avaliados os aspectos erosivos da superfície dos materiais. Todos os corpos-de-prova foram avaliados ao microscópio eletrônico de varredura e comparados com cinco outros corpos-de-prova de cada material, confeccionados da mesma forma e que serviram como controle. Todos os materiais estudados sofreram ação erosiva dos meios, com características distintas, devido às suas diferentes composições, após serem submetidos à simulação in vitro

  14. Dietary supplement intake during pregnancy; better safe than sorry?

    Science.gov (United States)

    de Boer, Alie; Bast, Aalt; Godschalk, Roger

    2018-06-01

    Consumption of dietary supplements and specifically niche products such as supplements targeting pregnant women is increasing. The advantages of dietary supplementation during pregnancy with folic acid have been established, but health effects of many other supplements have not been confirmed. EU and US legislation on dietary supplements requires the product to be safe for the direct consumer, the mother. Long-term health effects for the fetus due to fetal programming (in utero adaptation of the fetal epigenome due to environmental stimuli such as supplementation) are not taken into account. Such epigenetic alterations can, however, influence the response to health challenges in adulthood. We therefore call for both conducting research in birth cohorts and animal studies to identify potential health effects in progeny of supplement consuming mothers as well as the establishment of a nutrivigilance scheme to identify favorable and adverse effects post-marketing. The acquired knowledge can be used to create more effective legislation on dietary supplement intake during pregnancy for safety of the child. Increasing knowledge on the effects of consuming supplements will create a safer environment for future mothers and their offspring to optimize their health before, during and after pregnancy. Copyright © 2018 Elsevier Inc. All rights reserved.

  15. EURDYN: computer programs for the nonlinear transient analysis of structures submitted to dynamic loading. EURDYN (Release 3): users' manual

    International Nuclear Information System (INIS)

    Halleux, J.P.

    1983-01-01

    The EURDYN computer codes are mainly designed for the simulation of nonlinear dynamic response of fast-reactor compoments submitted to impulse loading due to abnormal working conditions. Two releases of the structural computer codes EURDYN 01 (2-D beams and triangles and axisymmetric conical shells and triangular tores), 02 (axisymmetric and 2-D quadratic isoparametric elements) and 03 (triangular plate elements) have already been produced. They include material (elasto-plasticity using the classical flow theory approach) and geometrical (large displacements and rotations treated by a corotational technique) nonlinearities. The new features of Release 3 roughly consist in: full large strain capability for 9-node isoparametric elements, generalized array dimensions, introduction of the radial return algorithm for elasto-plastic material modelling, extension of the energy check facility to the case of prescribed displacements, and, possible interface to a post-processing package including time plot facilities

  16. Implementing a "quality by design" approach to assure the safety and integrity of botanical dietary supplements.

    Science.gov (United States)

    Khan, Ikhlas A; Smillie, Troy

    2012-09-28

    Natural products have provided a basis for health care and medicine to humankind since the beginning of civilization. According to the World Health Organization (WHO), approximately 80% of the world population still relies on herbal medicines for health-related benefits. In the United States, over 42% of the population claimed to have used botanical dietary supplements to either augment their current diet or to "treat" or "prevent" a particular health-related issue. This has led to the development of a burgeoning industry in the U.S. ($4.8 billion per year in 2008) to supply dietary supplements to the consumer. However, many commercial botanical products are poorly defined scientifically, and the consumer must take it on faith that the supplement they are ingesting is an accurate representation of what is listed on the label, and that it contains the purportedly "active" constituents they seek. Many dietary supplement manufacturers, academic research groups, and governmental organizations are progressively attempting to construct a better scientific understanding of natural products, herbals, and botanical dietary supplements that have co-evolved with Western-style pharmaceutical medicines. However, a deficiency of knowledge is still evident, and this issue needs to be addressed in order to achieve a significant level of safety, efficacy, and quality for commercial natural products. The authors contend that a "quality by design" approach for botanical dietary supplements should be implemented in order to ensure the safety and integrity of these products. Initiating this approach with the authentication of the starting plant material is an essential first step, and in this review several techniques that can aid in this endeavor are outlined.

  17. 13 CFR 120.830 - Reports a CDC must submit.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Reports a CDC must submit. 120.830 Section 120.830 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development... each new associate and staff, a Statement of Personal History (for use by non-bank lenders and CDCs...

  18. 42 CFR 1008.11 - Who may submit a request.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Who may submit a request. 1008.11 Section 1008.11 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG... advisory opinion regarding an existing arrangement or one which the requestor in good faith specifically...

  19. 78 FR 63183 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Mobile...

    Science.gov (United States)

    2013-10-23

    ... promulgated under SNAP require that Motor Vehicle Air Conditioners (MVACs) retrofitted to use a SNAP... Request Submitted to OMB for Review and Approval; Comment Request; Mobile Air Conditioner Retrofitting... Environmental Protection Agency has submitted an information collection request (ICR), Mobile Air Conditioner...

  20. Radioiodine-induced oxidative stress in patients with differentiated thyroid carcinoma and effect of supplementation with vitamins C and E and selenium (antioxidants)

    Energy Technology Data Exchange (ETDEWEB)

    Rosario, Pedro Weslley; Batista, Kelly Cristina Siqueira; Calsolari, Maria Regina, E-mail: pedrowsrosario@gmail.com [Santa Casa de Belo Horizonte, MG (Brazil)

    2016-11-01

    The objective of this study, in addition to confirming that therapy with {sup 131}I causes oxidative stress, was to evaluate the effect of supplementation with vitamins C and E and selenium on this phenomenon by measuring plasma 8-epi-PGF2α, a marker of lipid peroxidation. Subjects and methods: Forty patients with thyroid cancer submitted to thyroidectomy, who received 3.7 GBq {sup 131}I after levothyroxine withdrawal, were selected; 20 patients did not receive (control group) and 20 patients received (intervention group) daily supplementation consisting of 2000 mg vitamin C, 1000 mg vitamin E and 400 μg selenium for 21 days before {sup 131}I. Plasma 8-epi-PGF2α was measured immediately before and 2 and 7 days after {sup 131}I. Results: A significant increase in plasma 8-epi-PGF2α after {sup 131}I was observed in the two groups. The concentrations of 8-epi-PGF2α were significantly higher in the control group before and 2 and 7 days after {sup 131}I. The percentage of patients with elevated 8-epi-PGF2α was also significantly higher in the control group before and after {sup 131}I. Furthermore, the increase (percent) in 8-epi-PGF2α was significantly greater in the control group (average of 112.3% versus 56.3%). Only two patients (10%) reported side effects during supplementation. Conclusions: Ablation with {sup 131}I causes oxidative stress which can be minimized by the use of antioxidants. (author)

  1. Overview of NASA's Microgravity Materials Science Program

    Science.gov (United States)

    Downey, James Patton

    2012-01-01

    The microgravity materials program was nearly eliminated in the middle of the aughts due to budget constraints. Hardware developments were eliminated. Some investigators with experiments that could be performed using ISS partner hardware received continued funding. Partnerships were established between US investigators and ESA science teams for several investigations. ESA conducted peer reviews on the proposals of various science teams as part of an ESA AO process. Assuming he or she was part of a science team that was selected by the ESA process, a US investigator would submit a proposal to NASA for grant funding to support their part of the science team effort. In a similar manner, a US materials investigator (Dr. Rohit Trivedi) is working as a part of a CNES selected science team. As funding began to increase another seven materials investigators were selected in 2010 through an NRA mechanism to perform research related to development of Materials Science Research Rack investigations. One of these has since been converted to a Glovebox investigation.

  2. Commonly Used Dietary Supplements on Coagulation Function during Surgery

    Directory of Open Access Journals (Sweden)

    Chong-Zhi Wang

    2015-07-01

    Full Text Available Background: Patients who undergo surgery appear to use dietary supplements significantly more frequently than the general population. Because they contain pharmacologically active compounds, dietary supplements may affect coagulation and platelet function during the perioperative period through direct effects, pharmacodynamic interactions, and pharmacokinetic interactions. However, in this regard, limited studies have been conducted that address the pharmacological interactions of dietary supplements. To avoid possible bleeding risks during surgery, information about the potential complications of dietary supplements during perioperative management is important for physicians. Methods: Through a systematic database search of all available years, articles were identified in this review if they included dietary supplements and coagulation/platelet function, while special attention was paid to studies published after 1990. Results: Safety concerns are reported in commercially available dietary supplements. Effects of the most commonly used natural products on blood coagulation and platelet function are systematically reviewed, including 11 herbal medicines (echinacea, ephedra, garlic, ginger, ginkgo, ginseng, green tea, kava, saw palmetto, St John’s wort, and valerian and four other dietary supplements (coenzyme Q10, glucosamine and chondroitin sulfate, fish oil, and vitamins. Bleeding risks of garlic, ginkgo, ginseng, green tea, saw palmetto, St John’s wort, and fish oil are reported. Cardiovascular instability was observed with ephedra, ginseng, and kava. Pharmacodynamic and pharmacokinetic interactions between dietary supplements and drugs used in the perioperative period are discussed. Conclusions: To prevent potential problems associated with the use of dietary supplements, physicians should be familiar with the perioperative effects of commonly used dietary supplements. Since the effects of dietary supplements on coagulation and platelet

  3. Commonly Used Dietary Supplements on Coagulation Function during Surgery

    Science.gov (United States)

    Wang, Chong-Zhi; Moss, Jonathan; Yuan, Chun-Su

    2015-01-01

    Abstract Background Patients who undergo surgery appear to use dietary supplements significantly more frequently than the general population. Because they contain pharmacologically active compounds, dietary supplements may affect coagulation and platelet function during the perioperative period through direct effects, pharmacodynamic interactions, and pharmacokinetic interactions. However, in this regard, limited studies have been conducted that address the pharmacological interactions of dietary supplements. To avoid possible bleeding risks during surgery, information about the potential complications of dietary supplements during perioperative management is important for physicians. Methods Through a systematic database search of all available years, articles were identified in this review if they included dietary supplements and coagulation/platelet function, while special attention was paid to studies published after 1990. Results Safety concerns are reported in commercially available dietary supplements. Effects of the most commonly used natural products on blood coagulation and platelet function are systematically reviewed, including 11 herbal medicines (echinacea, ephedra, garlic, ginger, ginkgo, ginseng, green tea, kava, saw palmetto, St John’s wort, and valerian) and four other dietary supplements (coenzyme Q10, glucosamine and chondroitin sulfate, fish oil, and vitamins). Bleeding risks of garlic, ginkgo, ginseng, green tea, saw palmetto, St John’s wort, and fish oil are reported. Cardiovascular instability was observed with ephedra, ginseng, and kava. Pharmacodynamic and pharmacokinetic interactions between dietary supplements and drugs used in the perioperative period are discussed. Conclusions To prevent potential problems associated with the use of dietary supplements, physicians should be familiar with the perioperative effects of commonly used dietary supplements. Since the effects of dietary supplements on coagulation and platelet function are

  4. Commonly Used Dietary Supplements on Coagulation Function during Surgery.

    Science.gov (United States)

    Wang, Chong-Zhi; Moss, Jonathan; Yuan, Chun-Su

    2015-09-01

    Patients who undergo surgery appear to use dietary supplements significantly more frequently than the general population. Because they contain pharmacologically active compounds, dietary supplements may affect coagulation and platelet function during the perioperative period through direct effects, pharmacodynamic interactions, and pharmacokinetic interactions. However, in this regard, limited studies have been conducted that address the pharmacological interactions of dietary supplements. To avoid possible bleeding risks during surgery, information of potential complications of dietary supplements during perioperative management is important for physicians. Through a systematic database search of all available years, articles were identified in this review if they included dietary supplements and coagulation/platelet function, while special attention was paid to studies published after 1990. Safety concerns are reported in commercially available dietary supplements. Effects of the most commonly used natural products on blood coagulation and platelet function are systematically reviewed, including 11 herbal medicines (echinacea, ephedra, garlic, ginger, ginkgo, ginseng, green tea, kava, saw palmetto, St John's wort, and valerian) and 4 other dietary supplements (coenzyme Q 10 , glucosamine and chondroitin sulfate, fish oil, and vitamins). Bleeding risks of garlic, ginkgo, ginseng, green tea, saw palmetto, St John's wort, and fish oil are reported. Cardiovascular instability was observed with ephedra, ginseng, and kava. Pharmacodynamic and pharmacokinetic interactions between dietary supplements and drugs used in the perioperative period are discussed. To prevent potential problems associated with the use of dietary supplements, physicians should be familiar with the perioperative effects of commonly used dietary supplements. Since the effects of dietary supplements on coagulation and platelet function are difficult to predict, it is prudent to advise their

  5. Characterization of inorganic components in nutritional supplements by neutron activation analysis

    International Nuclear Information System (INIS)

    Reis, Rogerio Alves de Sousa

    2006-01-01

    The control of element composition in nutritional supplements is of great interest due to increasingly high consumption and a large diversity and brands of these products offered in market. Therefore, there is the necessity to evaluate the element contents in the supplements and to compare with those values declared on the labels. In this study neutron activation analysis (NAA) was applied to evaluate the element composition of 11 commercial nutritional supplement brands bought in natural product drugstores and pharmacies. These samples acquired in capsule or tablet forms were ground to a homogeneous powder. The samples were irradiated together with the elemental standards in the IEA-R1 nuclear research reactor. Irradiations of 8 h under a thermal neutron flux of 5 x 10 12 n cm -2 s -1 were carried out for Ca, Co, Cr, Fe, Se and Zn determinations. For Cu, K and Na determinations thermal neutron flux of 1 x 10 12 n cm -s-1 was used and, the exposure time was 1h. The induced gamma activities were measured using a hyper pure Ge detector coupled to a gamma ray spectrometer. The obtained results compared with the values of the labels of nutritional supplements presented good agreement for most of the elements. Toxic elements such as As, Cd, Hg and Sb were not detected in the samples. For quality control of the analytical data, certified reference materials NIST 1400 Bone Ash and NIST 1633b Coal Fly Ash provided by the National Institute of Standards and Technology were also analysed. Accuracy and precision of these results were evaluated. The obtained Z score values were lower than 2 indicating that the data are within the ranges of certified values at 95% confidence level (author)

  6. Side effects of creatine supplementation in athletes.

    OpenAIRE

    Francaux, Marc; Poortmans, Jacques R

    2006-01-01

    Context: Allegations about side effects of creatine supplementation by athletes have been published in the popular media and scientific publications. Purpose: To examine the experimental evidence relating to the physiological effects of creatine supplementation. Results: One of the purported effects of oral creatine supplementation is increased muscle mass. A review of the literature reveals a 1.0% to 2.3% increase in body mass, which is attributed to fat-free mass and, more specifically, to ...

  7. Profiling the Use of Dietary Supplements by Brazilian Physical Education Professionals.

    Science.gov (United States)

    Viana, Ricardo Borges; Silva, Maria Sebastiana; da Silva, Wellington Fernando; Campos, Mário Hebling; Andrade, Marília Dos Santos; Vancini, Rodrigo Luiz; Andre Barbosa de Lira, Claudio

    2017-12-27

    A survey was designed to examine the use of dietary supplements by Brazilian physical education professionals. The study included 131 Brazilian physical education professionals (83 men and 48 women). A descriptive statistical analysis was performed (mean, standard deviation, and absolute and relative frequencies). A chi-square test was applied to evaluate differences in use of dietary supplements according to particular variables of interest (p supplements. Approximately 59% of dietary supplement users took two or more kinds of supplements. Among users of supplements, men professionals (73%) consumed more dietary supplements than women (27%). The most-consumed dietary supplement was whey protein (80%). The results showed a higher use of dietary supplements by men. The most-consumed supplements were rich in protein. The consumption of dietary supplements by almost half of the participants in this study suggests that participants did not consider their dietary needs to be met by normal diet alone.

  8. High Temperature Materials Laboratory User Program: 19th Annual Report, October 1, 2005 - September 30, 2006

    Energy Technology Data Exchange (ETDEWEB)

    Pasto, Arvid [ORNL

    2007-08-01

    Annual Report contains overview of the High Temperature Materials Laboratory User Program and includes selected highlights of user activities for FY2006. Report is submitted to individuals within sponsoring DOE agency and to other interested individuals.

  9. Effect of selenium supplementation on thyroid antibodies

    International Nuclear Information System (INIS)

    Kvicala, J.; Hrda, P.; Zamrazil, V.; Nemecek, J.; Hill, M.; Jiranek, V.

    2009-01-01

    Selenium is an essential component of selenoproteins, enzymes with extensive regulatory and protective effect in organism. Immunological effects of Se are documented and are distinct even above concentrations necessary for maximal activity of selenoenzymes. Therefore, we investigated effect of supplementation by 100 μg of yeast-bound Se on concentrations of thyroid autoantibodies TPOAb and TgAb in the group of 253 seniors living in the Asylum Houses of South Bohemia. Increase of serum selenium from 59 to 150 μg Se/L serum in supplemented group and from 59 to 72 μg Se/L serum in group with placebo were detected by Instrumental Neutron Activation Analysis (INAA) and proved increased Se intake during the trial. Autoantibodies were analyzed by ELISA at the beginning of the trial and after 1 year. Statistical evaluation of results in whole groups (regardless of increased autoantibodies) by ANOVA manifested significant decrease of TPOAb and TgAb in non-supplemented group while supplementation did not effect serum autoantibodies concentrations. Evaluation of groups of seniors created from those with increased autoantibodies, ANOVA demonstrated decrease of TPOAb in both groups but Se supplementation did not affect the decrease. In opposite, TgAb increased significantly and Se supplementation led to higher increase of TgAb. Recent results of possibility to decrease serum concentration of TPOAb proved this effect only for high TPOAb concentrations and for higher Se supplements. From this point of view, it is necessary to conduct subsequent trials with the patients with autoimmune thyreoiditis with different levels of autoantibodies and detect also serum Se levels. (author)

  10. 30 CFR 75.361 - Supplemental examination.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Supplemental examination. 75.361 Section 75.361... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.361 Supplemental examination. (a) Except for certified persons conducting examinations required by this subpart, within 3 hours before anyone...

  11. 21 CFR 866.2450 - Supplement for culture media.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Supplement for culture media. 866.2450 Section 866...) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices § 866.2450 Supplement for culture media. (a) Identification. A supplement for culture media is a device, such as a vitamin or sugar...

  12. Radioactive 210Po in magnesium supplements

    International Nuclear Information System (INIS)

    Struminska-Parulska, Dagmara Ida

    2016-01-01

    The aim of this pioneer study was to determine polonium 210 Po in the most popular magnesium supplements in Poland and estimate the possible related dose assessment to the consumers. The analyzed magnesium pharmaceutics contained organic or inorganic magnesium compounds; some from natural sources. The objectives of this research were to investigate the naturally occurring 210 Po activity concentrations in magnesium supplements, find the correlations between 210 Po concentration in medicament and magnesium chemical form, and calculate the effective radiation dose connected to analyzed magnesium supplement consumption. The highest 210 Po activity concentrations were determined in mineral tablets made from sedimentary rocks, namely dolomite - 3.84 ± 0.15 mBq g -1 (sample Mg17). The highest annual radiation dose from 210 Po taken with 1 tablet of magnesium supplement per day or with 400 mg of pure Mg daily would come from sample Mg17 (dolomite) - 1.35 ± 0.5 and 8.44 ± 0.33 μSv year -1 respectively.

  13. Herbal remedies and supplements for weight loss

    Science.gov (United States)

    Weight loss - herbal remedies and supplements; Obesity - herbal remedies; Overweight - herbal remedies ... health care provider. Nearly all over-the-counter supplements with claims of weight-loss properties contain some ...

  14. 48 CFR 1352.213-71 - Instructions for submitting quotations under the simplified acquisition threshold-non-commercial.

    Science.gov (United States)

    2010-10-01

    ... submitting quotations under the simplified acquisition threshold-non-commercial. 1352.213-71 Section 1352.213... quotations under the simplified acquisition threshold—non-commercial. As prescribed in 48 CFR 1313.302-1-70, insert the following provision: Instructions for Submitting Quotations Under the Simplified Acquisition...

  15. An investigation of waste glass-based geopolymers supplemented with alumina

    Science.gov (United States)

    Christiansen, Mary U.

    An increased consideration of sustainability throughout society has resulted in a surge of research investigating sustainable alternatives to existing construction materials. A new binder system, called a geopolymer, is being investigated to supplement ordinary portland cement (OPC) concrete, which has come under scrutiny because of the CO2 emissions inherent in its production. Geopolymers are produced from the alkali activation of a powdered aluminosilicate source by an alkaline solution, which results in a dense three-dimensional matrix of tetrahedrally linked aluminosilicates. Geopolymers have shown great potential as a building construction material, offering similar mechanical and durability properties to OPC. Additionally, geopolymers have the added value of a considerably smaller carbon footprint than OPC. This research considered the compressive strength, microstructure and composition of geopolymers made from two types of waste glass with varying aluminum contents. Waste glass shows great potential for mainstream use in geopolymers due to its chemical and physical homogeneity as well as its high content of amorphous silica, which could eliminate the need for sodium silicate. However, the lack of aluminum is thought to negatively affect the mechanical performance and alkali stability of the geopolymer system. 39 Mortars were designed using various combinations of glass and metakaolin or fly ash to supplement the aluminum in the system. Mortar made from the high-Al glass (12% Al2O3) reached over 10,000 psi at six months. Mortar made from the low-Al glass (use in geopolymers, when care is given to consider the compositional and physical properties of the glass in mixture design.

  16. Assessment of surface hardness of acrylic resins submitted to accelerated artificial aging.

    Science.gov (United States)

    Tornavoi, D C; Agnelli, J A M; Lepri, C P; Mazzetto, M O; Botelho, A L; Soares, R G; Dos Reis, A C

    2012-06-01

    The aim of this study was to assess the influence of accelerated artificial aging (AAA) on the surface hardness of acrylic resins. The following three commercial brands of acrylic resins were tested: Vipi Flash (autopolymerized resin), Vipi Wave (microwave heat-polymerized resin) and Vipi Cril (conventional heat-polymerized resin). To perform the tests, 21 test specimens (65x10x3 mm) were made, 7 for each resin. Three surface hardness readings were performed for each test specimen, before and after AAA, and the means were submitted to the following tests: Kolmogorov-Smirnov (P>0.05), Levene Statistic, Two-way ANOVA, Tukey Post Hoc (Paging, the autopolymerized acrylic resin Vipi Flash showed lower hardness values when compared with the heat-polymerized resin Vipi Cril (P=0.001). After aging, the 3 materials showed similar performance when compared among them. The Vipi Cril was the only one affected by AAA and showed lower hardness values after this procedure (Pp=0.003). It may be concluded that accelerated artificial aging influenced surface hardness of heat-polymerized acrylic resin Vipi Cril.

  17. Properties of extruded snacks supplemented with amaranth grain grits

    Directory of Open Access Journals (Sweden)

    Hadnađev Miroslav S.

    2009-01-01

    Full Text Available Extruded amaranth grain products have specific aroma and can be used as snack food, supplement in breakfast cereals, or as raw material for further processing. Extruded products of corn-amaranth grits blends, containing 20% or 50% amaranth grain grits, were produced by extrusion-cooking using a laboratory Brabender single screw extruder 20 DN. Extrudates with various texture were obtained. During extrusion process starch granules are partially degraded, hence rheological properties were examined. All samples exhibited thixotropic flow behavior. Those samples in which part of the corn grits was replaced with amaranth one had lower viscosity and exhibited lower level of structuration during storage.

  18. Dried, irradiated sewage solids as supplemental feed for cattle

    International Nuclear Information System (INIS)

    Smith, G.S.; Kiesling, H.E.; Ray, E.E.; Orcasberro, R.; Trujillo, P.; Herbel, C.H.; Sivinski, J.S.

    1980-01-01

    Sewage solids were collected as 'primary settled solids' and then dried and gamma-irradiated (using 60 Co or 177 Cs) to absorbed dosage of about one magarad to minimize viable parasites and pathogenic organisms. Nutrient composition and bioassays suggested prospective usage as supplemental feed for ruminants. In a large-scale experiment, beef cows grazing poor-quality rangeland forage during late gestation-early lactation were given either no supplemental feed or cottonseed meal or experimental supplement comprised of 62% sewage solids. Supplements were provided for 13 weeks until rangeland forage quality improved seasonably. Supplemental cottenseed meal for cows improved weaning weights of calves by about 11% over unsupplemented controls; whereas, supplement with 62% sewage solids improved calf weaning weights by about 7%. Hazards or risks to animals or to human health appear to be slight when sewage solids of this type are fed as supplemental feeds to cattle in production programs of this type. (Auth.)

  19. EFFECT OF SHORT-TERM CAFFEINE SUPPLEMENTATION ON STRESS RESPONSE AND IMMUNE SYSTEM OF MALE ATHLETES

    Directory of Open Access Journals (Sweden)

    Asghar Tofighi

    2014-03-01

    Full Text Available Vigorous exercise stress might be leading cause of immune system disorders and appearance of acute and chronic inflammation in human body. Caffeine supplementation prior to exercise can be effective on body immune response. This study aimed to evaluate the effect of short-term caffeine supplementation on immune response and stress index in male athletes after an exhaustive aerobic exercise. Materials and methods : In a double-blind study 24 male athletes (endurance runner and triathlon randomly divided in Caffeine supplementation (CAF and Placebo (CON groups. One hour prior to main exhaustive treadmill test (Bruce test CAF group consumed caffeine (6 Mg/BW and CON group received placebo. Blood samples were collected before and immediately after exercise test from anticubital vein. After supplying serum; Cortisol, leukocyte and serum Heat shock protein 72 (Hsp72 concentrations were determined using ELISA method. Paired and independent t student test was used for analysis of inter and intra group differences respectively. Results: serum cortisol and Hsp72 concentrations in CON group was significantly higher than CAF group (P0.05. In addition Mean of variation in CON group was significantly higher than CAF group (P<0.05. Conclusions: Based on study results caffeine supplementation prior to short-term exhaustive aerobic exercise has positive effect on innate immunity and body defensive system.

  20. EFFECT OF SHORT-TERM CAFFEINE SUPPLEMENTATION ON STRESS RESPONSE AND IMMUNE SYSTEM OF MALE ATHLETES

    Directory of Open Access Journals (Sweden)

    Asghar Tofighi

    2014-04-01

    Full Text Available Vigorous exercise stress might be leading cause of immune system disorders and appearance of acute and chronic inflammation in human body. Caffeine supplementation prior to exercise can be effective on body immune response. This study aimed to evaluate the effect of short-term caffeine supplementation on immune response and stress index in male athletes after an exhaustive aerobic exercise. Materials and methods : In a double-blind study 24 male athletes (endurance runner and triathlon randomly divided in Caffeine supplementation (CAF and Placebo (CON groups. One hour prior to main exhaustive treadmill test (Bruce test CAF group consumed caffeine (6 Mg/BW and CON group received placebo. Blood samples were collected before and immediately after exercise test from anticubital vein. After supplying serum; Cortisol, leukocyte and serum Heat shock protein 72 (Hsp72 concentrations were determined using ELISA method. Paired and independent t student test was used for analysis of inter and intra group differences respectively. Results: serum cortisol and Hsp72 concentrations in CON group was significantly higher than CAF group (P0.05. In addition Mean of variation in CON group was significantly higher than CAF group (P<0.05. Conclusions: Based on study results caffeine supplementation prior to short-term exhaustive aerobic exercise has positive effect on innate immunity and body defensive system.

  1. Effect of water electrolyte supplementation on performance, serum ...

    African Journals Online (AJOL)

    Under heat stress, 0.5% KCl and 0.5%NaCl supplementation in water reduced rectal temperature, increased body weight, improved FCR, and reduced blood pH. Electrolyte supplementation also influenced red blood cell count as well as serum levels of sodium, potassium and bicarbonate. Supplementing KCl and NaCl in ...

  2. Potential harmful effects of dietary supplements in sports medicine.

    Science.gov (United States)

    Deldicque, Louise; Francaux, Marc

    2016-11-01

    The purpose of this article is to collect the most recent data regarding the safety of well-known or emerging dietary supplements used by athletes. From January 2014 to April 2016, about 30 articles have been published in the field. New data show that 90% of sports supplements contain trace of estrogenic endocrine disruptors, with 25% of them having a higher estrogenic activity than acceptable. About 50% of the supplements are contaminated by melamine, a source of nonprotein nitrogen. Additional data accumulate toward the safety of nitrate ingestion. In the last 2 years, the safety of emerging supplements such as higenamine, potentially interesting to lose weight, creatine nitrate and guanidinoacetic acid has been evaluated but still needs further investigation. The consumption of over-the-counter supplements is very popular in athletes. Although most supplements may be considered as safe when taking at the recommended doses, athletes should be aware of the potential risks linked to the consumption of supplements. In addition to the risks linked to overdosage and cross-effects when combining different supplements at the same time, inadvertent or deliberate contamination with stimulants, estrogenic compounds, diuretics or anabolic agents may occur.

  3. Corrosion of Nickel-Titanium Orthodontic Archwires in Saliva and Oral Probiotic Supplements

    Directory of Open Access Journals (Sweden)

    Gianluca Turco

    2017-01-01

    Full Text Available Objectives: The aim of the study was to examine how probiotic supplements affect the corrosion stability of orthodontic archwires made of nickel-titanium alloy (NiTi. Materials and Methods: Ni-Ti archwires (0.508x0.508 and having the length of 2.5 cm were tested. The archwires (composition Ni=50.4%, Ti=49.6% were uncoated, nitrified and rhodium coated. Surface microgeometry was observed by using scanning electron microscope and surface roughness was measured by profilometer through these variables: roughness average, maximum height and maximum roughness depth. Corrosion was examined by electrochemical method of cyclic polarisation. Results: Rhodium coated alloy in saliva has significantly higher general corrosion in saliva than nitrified alloy and uncoated alloy, with large effect size (p=0.027; η2=0.700. In the presence of probiotics, the result was even more pronounced (p<0.001; η2=0.936. Probiotic supplement increases general and localised corrosion of rhodium coated archwire and slightly decreases general corrosion and increases localised corrosion in uncoated archwire , while in the case of nitrified archwire the probability of corrosion is very low. The differences in surface roughness between NiTi wires before corrosion are not significant. Exposure to saliva decreases roughness average in rhodium coated wire (p=0.015; η2=0.501. Media do not significantly influence surface microgeometry in nitrified and uncoated wires. Conclusion: Probiotic supplement affects corrosion depending on the type of coating of the NiTi archwire. It increases general corrosion of rhodium coated wire and causes localised corrosion of uncoated and rhodium coated archwire. Probiotic supplement does not have greater influence on surface roughness compared to that of saliva.

  4. Dietary Supplements: Regulatory Challenges and Research Resources

    OpenAIRE

    Johanna T. Dwyer; Paul M. Coates; Michael J. Smith

    2018-01-01

    Many of the scientific and regulatory challenges that exist in research on the safety, quality and efficacy of dietary supplements are common to all countries as the marketplace for them becomes increasingly global. This article summarizes some of the challenges in supplement science and provides a case study of research at the Office of Dietary Supplements at the National Institutes of Health, USA, along with some resources it has developed that are available to all scientists. It includes e...

  5. Dietary supplement usage and motivation in Brazilian road runners.

    Science.gov (United States)

    Salgado, José Vítor Vieira; Lollo, Pablo Christiano Barboza; Amaya-Farfan, Jaime; Chacon-Mikahil, Mara PatríciaTraina

    2014-01-01

    The consumption of dietary supplements is highest among athletes and it can represent potential a health risk for consumers. The aim of this study was to determine the prevalence of consumption of dietary supplements by road runners. We interviewed 817 volunteers from four road races in the Brazilian running calendar. The sample consisted of 671 male and 146 female runners with a mean age of 37.9 ± 12.4 years. Of the sample, 28.33% reported having used some type of dietary supplement. The main motivation for this consumption is to increase in stamina and improve performance. The probability of consuming dietary supplements increased 4.67 times when the runners were guided by coaches. The consumption of supplements was strongly correlated (r = 0.97) with weekly running distance, and also highly correlated (r = 0.86) with the number of years the sport had been practiced. The longer the runner had practiced the sport, the higher the training volume and the greater the intake of supplements. The five most frequently cited reasons for consumption were: energy enhancement (29.5%), performance improvement (17.1%), increased level of endurance (10.3%), nutrient replacement (11.1%), and avoidance of fatigue (10.3%). About 30% of the consumers declared more than one reason for taking dietary supplements. The most consumed supplements were: carbohydrates (52.17%), vitamins (28.70%), and proteins (13.48%). Supplement consumption by road runners in Brazil appeared to be guided by the energy boosting properties of the supplement, the influence of coaches, and the experience of the user. The amount of supplement intake seemed to be lower among road runners than for athletes of other sports. We recommend that coaches and nutritionists emphasise that a balanced diet can meet the needs of physically active people.

  6. Glutamine Supplemented Parenteral Nutrition to Prevent Ventilator-Associated Pneumonia in the Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Meltem Türkay Aydoğmuş

    2012-12-01

    Full Text Available Objective: Ventilator-associated pneumonia (VAP is a form of nosocomial pneumonia that increases patient morbidity and mortality, length of hospital stay, and healthcare costs. Glutamine preserves the intestinal mucosal structure, increases immune function, and reduces harmful changes in gut permeability in patients receiving total parenteral nutrition (TPN. We hypothesized that TPN supplemented by glutamine might prevent the development of VAP in patients on mechanical ventilator support in the intensive care unit (ICU. Material and Methods: With the approval of the ethics committee and informed consent from relatives, 60 patients who were followed in the ICU with mechanical ventilator support were included in our study. Patients were divided into three groups. The first group received enteral nutrition (n=20, and the second was prescribed TPN (n=20 while the third group was given glutamine-supplemented TPN (n=20. C-reactive protein (CRP, sedimentation rate, body temperature, development of purulent secretions, increase in the amount of secretions, changes in the characteristics of secretions and an increase in requirement of deep tracheal aspiration were monitored for seven days by daily examination and radiographs. Results: No statistically significant difference was found among groups in terms of development of VAP (p=0.622. Conclusion: Although VAP developed at a lower rate in the glutamine-supplemented TPN group, no statistically significant difference was found among any of the groups. Glutamine-supplemented TPN may have no superiority over unsupplemented enteral and TPN in preventing VAP.

  7. Oral calorie supplements for cystic fibrosis.

    Science.gov (United States)

    Smyth, Rosalind L; Rayner, Oli

    2017-05-04

    Poor nutrition occurs frequently in people with cystic fibrosis and is associated with other adverse outcomes. Oral calorie supplements are used to increase total daily calorie intake and improve weight gain. However, they are expensive and there are concerns they may reduce the amount of food eaten and not improve overall energy intake. This is an update of a previously published review. To establish whether in people with cystic fibrosis, oral calorie supplements: increase daily calorie intake; and improve overall nutritional intake, nutritional indices, lung function, survival and quality of life. To assess adverse effects associated with using these supplements. We searched the Cochrane Cystic Fibrosis Trials Register comprising references from comprehensive electronic database searches, handsearches of relevant journals and abstract books of conference proceedings. We contacted companies marketing oral calorie supplements.Last search: 18 October 2016. Randomised or quasi-randomised controlled trials comparing use of oral calorie supplements for at least one month to increase calorie intake with no specific intervention or additional nutritional advice in people with cystic fibrosis. We independently selected the included trials, assessed risk of bias and extracted data. We contacted the authors of included trials and obtained additional information for two trials. We identified 21 trials and included three, reporting results from 131 participants lasting between three months and one year. Two trials compared supplements to additional nutritional advice and one to no intervention. Two of the included trials recruited only children. In one trial the risk of bias was low across all domains, in a second trial the risk of bias was largely unclear and in the third mainly low. Blinding of participants was unclear in two of the trials. Also, in one trial the clinical condition of groups appeared to be unevenly balanced at baseline and in another trial there were

  8. Effect of Vitamin D supplementation on glycemic parameters and progression of prediabetes to diabetes: A 1-year, open-label randomized study

    Directory of Open Access Journals (Sweden)

    Mohammad Shafi Kuchay

    2015-01-01

    Full Text Available Background: Whether Vitamin D supplementation in prediabetes subjects prevents the development of diabetes is a matter of debate, and the results are inconsistent. This open-label, randomized study in subjects with prediabetes evaluated the effect of 12 months of Vitamin D supplementation on glycemic parameters and progression of prediabetes to diabetes in an ethnically homogeneous Kashmiri population. Materials and Methods: A total of 147 subjects were diagnosed as prediabetes out of which 137 subjects were randomized to receive in addition to standard lifestyle measures, either Vitamin D 60,000 IU weekly for 4 weeks and then 60,000 IU monthly (n = 69 or no Vitamin D (n = 68. Fasting plasma glucose (FPG, 2-h plasma glucose and A1C levels were estimated at 0, 6 and 12 months. Changes in FPG, 2-h plasma glucose, A1C level and the proportion of subjects developing diabetes were assessed among 129 subjects. Results: At 12 months, A1C levels were significantly lesser (5.7% ± 0.4% in the Vitamin D supplemented group when compared with non-Vitamin D supplemented (6.0% ± 0.3%. Similarly, FPG (97 ± 7 and 2-h plasma glucose (132 ± 16 were significantly less in Vitamin D supplemented group as compared with non-Vitamin D supplemented group (FPG = 116 ± 6 and 2-h plasma glucose = 157 ± 25 at 12 months. Nine out of 65 in non-Vitamin D supplemented and seven out of 64 in the Vitamin D supplemented group developed diabetes. Conclusions: Vitamin D supplementation in prediabetes subjects significantly lowered FPG, 2-h plasma glucose and A1C levels.

  9. Hepatitis C and Dietary Supplements: What the Science Says

    Science.gov (United States)

    ... Integrative Health NCCIH Clinical Digest for health professionals Hepatitis C and Dietary Supplements: What the Science Says ... Thinkstock Clinical Guidelines, Scientific Literature, Info for Patients: Hepatitis C and Dietary Supplements Dietary Supplements Milk Thistle ...

  10. Vitamin K supplementation for cystic fibrosis.

    Science.gov (United States)

    Jagannath, Vanitha A; Thaker, Vidhu; Chang, Anne B; Price, Amy I

    2017-08-22

    Cystic fibrosis is a genetic disorder which can lead to multiorgan dysfunction. Malabsorption of fat and fat-soluble vitamins (A, D, E, K) may occur and can cause subclinical deficiencies of some of these vitamins. Vitamin K is known to play an important role in both blood coagulation and bone formation. Supplementation with vitamin K appears to be one way of addressing the deficiency, but there is very limited agreement on the appropriate dose and frequency of use of these supplements. This is an updated version of the review. To assess the effects of vitamin K supplementation in people with cystic fibrosis and to determine the optimal dose and route of administration of vitamin K for both routine and therapeutic use. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Trials Register comprising references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings.Most recent search: 30 January 2017. Randomised and quasi-randomised controlled trials of all preparations of vitamin K used as a supplement compared to either no supplementation (or placebo) at any dose or route and for any duration, in children or adults diagnosed with cystic fibrosis (by sweat test or genetic testing). Two authors independently screened papers, extracted trial details and assessed their risk of bias. Two trials (total of 32 participants) each lasting one month were included in the review and were assessed as having a moderate risk of bias. One was a dose-ranging parallel group trial in children (aged 8 to 18 years); and the other (with an older cohort) had a cross-over design comparing supplements to no treatment, but no separate data were reported for the first intervention period. Neither of the trials addressed any of the primary outcomes (coagulation, bone formation and quality of life). Both trials reported the restoration of serum vitamin K and undercarboxylated osteocalcin

  11. Study on structural materials used in thermonuclear fusion technology

    International Nuclear Information System (INIS)

    Billa, R.; Amaral, D.

    1995-01-01

    The main problem related to the construction of a thermonuclear fusion reactor is the absence of suitable materials for the process, concerning to temperature limits, heat flux and life time. The first wall is the most critical part of the structure, being submitted to radiation effects, ionic corrosion and coolant, besides thermal fatigue and tension produced by cyclical burning. The AISI 316(17-12SPH) stainless steel is used as structural material, which has a wide known database. This work proposes an alternative material study to be used in the future thermonuclear fusion reactors. As a option a study on the utilization of Cr-Mn(Fe-17 Mn-10 Cr-0,1 C) steels and their alloy variations is presented

  12. Pressure vessels supported in the soil submitted to axissymetrical loads

    International Nuclear Information System (INIS)

    Gouvea, J.P. de; Bevilacqua, L.

    1982-01-01

    A pressure vessel, spherical segment or vertical cylinder, is supported in the soil and submitted to axissymetrical loads. The soil is considered as a semi-infinite elastic solid and the support as a lattice. The method of rigidity is used. (E.G.) [pt

  13. Is vitamin C supplementation beneficial?

    DEFF Research Database (Denmark)

    Lykkesfeldt, Jens; Poulsen, Henrik Enghusen

    2010-01-01

    of the benefit:harm ratio of antioxidant supplements. We have examined the literature on vitamin C intervention with the intention of drawing a conclusion on its possible beneficial or deleterious effect on health and the result is discouraging. One of several important issues is that vitamin C uptake is tightly...... controlled, resulting in a wide-ranging bioavailability depending on the current vitamin C status. Lack of proper selection criteria dominates the currently available literature. Thus, while supplementation with vitamin C is likely to be without effect for the majority of the Western population due...... to saturation through their normal diet, there could be a large subpopulation with a potential health problem that remains uninvestigated. The present review discusses the relevance of the available literature on vitamin C supplementation and proposes guidelines for future randomised intervention trials....

  14. PROFESSIONAL CHALLENGES CONCERNING THE CALCULATION AND USE OF MATERIALITY

    OpenAIRE

    Daniel Botez

    2013-01-01

    Significance is an essential reference in the judgments of the economic environment. It talks about significant influence, meaningful, significant risk, significant accounting policies, and the like. In accounting and auditing is used the term "materiality" when the submit financial information, to evaluate the risk or partial information or investigating events using statistical sampling technique. Starting from the premise that the conceptual and practical approach of the threshold of signi...

  15. [Quality of pastas supplemented with rice bran].

    Science.gov (United States)

    Sangronis, E; Rebolledo, M A

    1997-06-01

    The objective of this research was to investigate the potential of using rice bran as an ingredient in pastas spaghetti type. Two of the pastas were made with semolina from durum as raw material, supplemented with 10 and 20% rice bran. The other two were made with granular flour and the same percentage of rice bran. Proximate composition of raw material was analyzed. Pastas were elaborated in a local industry. Composition, proximal, color, texture, and sensorial quality of pastas were determined. Protein content (13.9-15.0%), ash (1.47-3.09%) and dietary fiber (6.71-8.45%) of pastas increased according to the percentage of rice bran added. The hardest pastas were those elaborated with semolina from durum wheat and with a 10% of substitution. Also, they were the most yellow. The sensory panel found differences in quality among the pastas evaluated. Pastas with 10% rice bran had the best quality. The results demonstrated that is possible to elaborate pastas with 20% as maximum of rice bran resulting products with high protein, ash and dietetic fiber content, but some undesirable characteristics were given by the rice bran as white spots, wrinkles and color changes.

  16. HERBAL SUPPLEMENTS: CAUSE FOR CONCERN?

    OpenAIRE

    Paolo Borrione; Luigi Di Luigi; Nicola Maffulli; Fabio Pigozzi

    2008-01-01

    More than 1400 herbal products or herbal-derived compounds are commonly commercialised for health uses worldwide (Tyler, 1996). Herbs are considered dietary supplements, and therefore are subjected to a very limited form of regulation, and advertisements normally highlight their potential activities without mentioning any side effect. Also, herbs are generally believed to be 'natural', and hence safe. Many nutritional supplements contains herb compounds usually not present in the diet (e.g. G...

  17. Use of Dietary Supplements among Professional Athletes in Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Sulaiman O. Aljaloud

    2013-01-01

    Full Text Available The objective of this study was to understand the usage patterns of dietary supplements among professional athletes in Saudi Arabia. The survey consisted of sixteen questions divided into four categories: use of supplements, reason for consumption of supplements, personal beliefs about supplements, and behavior. The questionnaires were given to the three teams residing in Riyadh: Al Hilal, Al Nasr, and Al-Shabab. Out of the 105 athletes surveyed, we found that only 98 are currently taking dietary supplements and the mean age and standard deviation were 25.74±2.90. The survey results showed a high percentage of athletes (93.3%; n=98 using different dietary supplements throughout the season, 43.8% (n=43 reported using supplements for performance, and 32.6% (n=32 believed in health benefits as a reason for using dietary supplements. Our results showed that a total of 87 (88.7%, 81 (82.6%, and 51 (52.0% athletes are consuming sports drinks, vitamin C, and multivitamins, respectively. Meanwhile, those supplements ranking among the least used included omega 6 (18.6%, creatine (16.3%, and Ginkgo biloba (10.2%. A majority of athletes indicated that their use of supplements was for the purpose of improving their health and performance.

  18. Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: A double-blind, randomized study

    International Nuclear Information System (INIS)

    Lin, L.-C.; Que, Jenny; Lin, L.-K.; Lin, F.-C.

    2006-01-01

    Purpose: To determine whether zinc supplementation can accelerate the healing of mucositis and dermatitis after radiotherapy. Methods and Materials: In this double-blind study, patients were placed into two randomized groups (experimental and control) of 50 patients each. The groups were homogeneous with respect to medical history, tumor characteristics, and therapeutic details. The experimental group received a standard dose of a zinc supplement, and the control group was given a placebo. Results: Patients in the control group developed Grade 2 mucositis and dermatitis earlier and sooner than patients in the experimental group. There was also a significant difference in the development of Grade 3 mucositis and dermatitis between the two groups. Patients in the experimental group were found to have milder mucositis and dermatitis. Zinc supplementation did not show much benefit in those patients receiving concurrent chemotherapy or make a substantial impact on weight changes. Conclusions: Zinc supplementation used in conjunction with radiotherapy could postpone the development of severe mucositis and dermatitis for patients with cancers of the head and neck. Zinc supplementation can also alleviate the degree of mucositis and dermatitis. The impact of zinc on tumor growth and patient survival is under further investigation

  19. CATTLE PRODUCTIVE PERFORMANCE EVALUATION CONFINED SUBMITTED IMMUNOCASTRATION

    Directory of Open Access Journals (Sweden)

    J. M. Maluf

    2016-09-01

    Full Text Available In order to evaluate the performance and carcass characteristics of cattle cross breeds ½ Aberdeen Angus x ½Nelore and Nelore confined submitted to immunocastration 218 male animals were used, feedlot, averaging 342 kg, divided into three experimental groups, T1: 117 steers ½ Angus x ½ Nelore no castrated (ANC, T2: 51 Nelore steers uncastrated (NNC and T3: 50 Nellore steers immunocastrated (NIC. The experiment lasted 144 days of confinement. The selection of animals for group formation was according to the individual weight, breed, sex condition and age. For immunocastration it wasused Bopriva® vaccine. The rating was finished according to the parameter used by the meatpacking industry ranging from 1 to 5. The experimental design was completely randomized in three groups. For the analyzes the variables studied statistics were submitted to analysis of variance (ANOVA and Tukey test both at the 5% level of significance. The results showed differences (p <0.01 at various features of productive performance and carcass between treatments. For slaughter weight, the ANC animals were higher (with 582.1 kg to Nelore, regardless of sexual condition, and the NNC were in turn heavier than the NIC, 527.4 and 503.7 respectively. Finally, it observed that the use of immunocastration in Nellore animals provided a decrease in productive performance of confined animals, but provided better finish carcass similar to crossbred (ANC.

  20. Use of Nutrition Supplements for the Elderly

    OpenAIRE

    Tenglerová, Dana

    2014-01-01

    The primary goal of my thesis was to describe the use of food supplements by seniors. Most seniors use medications prescribed by physicians and some of them also use over-the-counter food supplements that are more easily accessible. Seniors, in particular, are susceptible to considering food supplements to be as efficient as medications under the incessant influence of massive advertising on TV and other media, and many of them are willing to spend considerable amounts from their income on su...