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Sample records for supervisor terry piper

  1. Terry Richardson

    DEFF Research Database (Denmark)

    Hansen-Hansen, Erik

    2004-01-01

    Fotografen Terry Richardson blander pornografi, humor og mode på sin helt egen facon. Og det sælger. Det har gjort ham til en af de mest indflydelsesrige modefotografer i verden. Men politisk korrekt, det er han ikke. Erik Hansen-Hansen forklarer fænomenet. Udgivelsesdato: Juli......Fotografen Terry Richardson blander pornografi, humor og mode på sin helt egen facon. Og det sælger. Det har gjort ham til en af de mest indflydelsesrige modefotografer i verden. Men politisk korrekt, det er han ikke. Erik Hansen-Hansen forklarer fænomenet. Udgivelsesdato: Juli...

  2. Interview of Terry Doyle

    CERN Multimedia

    CERN Video productions

    2012-01-01

    An Interview with Terry Doyle, Director of Corporate Development, Nokia. This is part of a series of interviews organized by the SMS Interest Group of Strategy Practice, as part of the preparation for the 2013 SMS Special conference at Lake Geneva which is co-sponsored by ATLAS/CERN. For more information: http://geneva.strategicmanagement.net The purpose of the interviews is to provide input for academics, business practitioners and consultants about fundamental questions of strategy in enterprises.

  3. The Terry Biopsy Needle

    Science.gov (United States)

    Bond, Alan F.; Murphy, Fergus A.; Nanson, Eric M.

    1963-01-01

    Six illustrative cases are reported to demonstrate the versatility of the Terry biopsy needle as a useful instrument for obtaining satisfactory biopsy specimens from the liver and from other tissues as well. The apparatus and method of use are described and illustrated. ImagesFig. 1Fig. 2Fig. 3Fig. 4Fig. 5Fig. 6aFig. 6bFig. 7Fig. 8Fig. 9Fig. 10Fig. 11 PMID:13968726

  4. Terry Pratchetti südamlik triloogia

    Index Scriptorium Estoniae

    2008-01-01

    Tutvustus: Pratchett, Terry. Autojuhid / inglise keelest tõlkinud Allan Eichenbaum. Tallinn : Varrak, 2008 ; Pratchett, Terry. Kaevajad / inglise keelest tõlkinud Allan Eichenbaum. Tallinn : Varrak, 2008 ; Pratchett, Terry. Tiivad / inglise keelest tõlkinud Allan Eichenbaum. Tallinn : Varrak, 2008

  5. Terry Pratchetti südamlik triloogia

    Index Scriptorium Estoniae

    2008-01-01

    Tutvustus: Pratchett, Terry. Autojuhid / inglise keelest tõlkinud Allan Eichenbaum. Tallinn : Varrak, 2008 ; Pratchett, Terry. Kaevajad / inglise keelest tõlkinud Allan Eichenbaum. Tallinn : Varrak, 2008 ; Pratchett, Terry. Tiivad / inglise keelest tõlkinud Allan Eichenbaum. Tallinn : Varrak, 2008

  6. Supervisor Feedback.

    Science.gov (United States)

    Hayman, Marilyn J.

    1981-01-01

    Investigated the effectiveness of supervisor feedback in contributing to learning counseling skills. Counselor trainees (N=64) were assigned to supervisor feedback, no supervisor feedback, or control groups for three training sessions. Results indicated counseling skills were learned best by students with no supervisor feedback but self and peer…

  7. Supervisor training

    DEFF Research Database (Denmark)

    Pedersen, Inge Nygaard

    2015-01-01

    This article fills a gap in knowledge about supervisor training programmes in the field of music therapy in Europe. Sparse research exists which demonstrates evidence of effective professional supervision upon the outcome of music therapy clinical practice. The article has its focus on the experi......This article fills a gap in knowledge about supervisor training programmes in the field of music therapy in Europe. Sparse research exists which demonstrates evidence of effective professional supervision upon the outcome of music therapy clinical practice. The article has its focus...... on the experience of an integrated supervisor training programme offered in Aalborg, Denmark in 2009/2010. In this programme general issues of professional supervision and the application of artistic media as a core element in the supervisory process were Integrated. It is the hope of the author that this article...... will inspire other music therapists to develop supervisor training programmes for professional music therapists and also to undertake further research into professional supervision....

  8. Terry Miller : Eesti on majandusvabaduse maailmas kangelane

    Index Scriptorium Estoniae

    2008-01-01

    Majanduskonverentsil Restart esinenud pikaajalise kogemusega karjääridiplomaadi Terry Milleri hinnang Eesti majandusvabadusele. Eesti on maailma majandusvabaduse indeksi 12. kohal, kuid tööturu vabaduse osas on Eesti viimaste hulgas. Lisa: Majandusvabadus suurendab rahvuslikku rikkust

  9. Terry Miller : Eesti on majandusvabaduse maailmas kangelane

    Index Scriptorium Estoniae

    2008-01-01

    Majanduskonverentsil Restart esinenud pikaajalise kogemusega karjääridiplomaadi Terry Milleri hinnang Eesti majandusvabadusele. Eesti on maailma majandusvabaduse indeksi 12. kohal, kuid tööturu vabaduse osas on Eesti viimaste hulgas. Lisa: Majandusvabadus suurendab rahvuslikku rikkust

  10. Alkaloids from Piper sarmentosum and Piper nigrum.

    Science.gov (United States)

    Ee, G C L; Lim, C M; Lim, C K; Rahmani, M; Shaari, K; Bong, C F J

    2009-01-01

    Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids. The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). Piper nigrum roots gave pellitorine (2), (E)-1-[3',4'-(methylenedioxy)cinnamoyl]piperidine (3), 2,4-tetradecadienoic acid isobutyl amide (4), piperine (5), sylvamide (6), cepharadione A (7), piperolactam D (8) and paprazine (9). Structural elucidation of these compounds was achieved through NMR and MS techniques. Cytotoxic activity screening of the plant extracts indicated some activity.

  11. Profile Terry Young: man of the match

    CERN Multimedia

    2003-01-01

    Terry Young, chair of health systems at Brunel University, has received a grant of 3.3 million pounds from EPSRC. The money will create the Multidisciplinary Assessment of Technology Centre for Health (MATCH). The aim of the centre is to aid the progress of medical devices from concept to patient care by developing criteria to single out promising technologies and helping them to market (1 page).

  12. Piper J-3 Cub

    Science.gov (United States)

    1939-01-01

    Piper J-3 Cub: This Piper J-3 Cub was used to test a fixed-pitch propeller at the NACA's Langley Memorial Aeronautical Laboratory. These tests took place in late September and early October 1939. The NACA installed test instrumentation including the sensors mounted on the boom above the cockpit. Mounted in this manner, the sensors were free of the accelerated airflow around the Cub.

  13. PIPER and Polarized Galactic Foregrounds

    Science.gov (United States)

    Chuss, David

    2009-01-01

    In addition to probing inflationary cosmology, PIPER will measure the polarized dust emission from the Galaxy. PIPER will be capable of full (I,0,U,V) measurement over four frequency bands ' These measurements will provide insight into the physics of dust grains and a probe of the Galactic magnetic field on large and intermediate scales.

  14. PIPER and Polarized Galactic Foregrounds

    Science.gov (United States)

    Chuss, David

    2009-01-01

    In addition to probing inflationary cosmology, PIPER will measure the polarized dust emission from the Galaxy. PIPER will be capable of full (I,0,U,V) measurement over four frequency bands ' These measurements will provide insight into the physics of dust grains and a probe of the Galactic magnetic field on large and intermediate scales.

  15. The Terri Schiavo case: legal, ethical, and medical perspectives.

    Science.gov (United States)

    Perry, Joshua E; Churchill, Larry R; Kirshner, Howard S

    2005-11-15

    Although tragic, the plight of Terri Schiavo provides a valuable case study. The conflicts and misunderstandings surrounding her situation offer important lessons in medicine, law, and ethics. Despite media saturation and intense public interest, widespread confusion lingers regarding the diagnosis of persistent vegetative state, the judicial processes involved, and the appropriateness of the ethical framework used by those entrusted with Terri Schiavo's care. First, the authors review the current medical understanding of persistent vegetative state, including the requirements for patient examination, the differential diagnosis, and the practice guidelines of the American Academy of Neurology regarding artificial nutrition and hydration for patients with this diagnosis. Second, they examine the legal history, including the 2000 trial, the 2002 evidentiary hearing, and the subsequent appeals. The authors argue that the law did not fail Terri Schiavo, but produced the highest-quality evidence and provided the most judicial review of any end-of-life guardianship case in U.S. history. Third, they review alternative ethical frameworks for understanding the Terri Schiavo case and contend that the principle of respect for autonomy is paramount in this case and in similar cases. Far from being unusual, the manner in which Terri Schiavo's case was reviewed and the basis for the decision reflect a broad medical, legal, and ethical consensus. Greater clarity regarding the persistent vegetative state, less apprehension of the presumed mysteries of legal proceedings, and greater appreciation of the ethical principles at work are the chief benefits obtained from studying this provocative case.

  16. Research in the Mont Terri Rock laboratory: Quo vadis?

    Science.gov (United States)

    Bossart, Paul; Thury, Marc

    During the past 10 years, the 12 Mont Terri partner organisations ANDRA, BGR, CRIEPI, ENRESA, FOWG (now SWISSTOPO), GRS, HSK, IRSN, JAEA, NAGRA, OBAYASHI and SCK-CEN have jointly carried out and financed a research programme in the Mont Terri Rock Laboratory. An important strategic question for the Mont Terri project is what type of new experiments should be carried out in the future. This question has been discussed among partner delegates, authorities, scientists, principal investigators and experiment delegates. All experiments at Mont Terri - past, ongoing and future - can be assigned to the following three categories: (1) process and mechanism understanding in undisturbed argillaceous formations, (2) experiments related to excavation- and repository-induced perturbations and (3) experiments related to repository performance during the operational and post-closure phases. In each of these three areas, there are still open questions and hence potential experiments to be carried out in the future. A selection of key issues and questions which have not, or have only partly been addressed so far and in which the project partners, but also the safety authorities and other research organisations may be interested, are presented in the following. The Mont Terri Rock Laboratory is positioned as a generic rock laboratory, where research and development is key: mainly developing methods for site characterisation of argillaceous formations, process understanding and demonstration of safety. Due to geological constraints, there will never be a site specific rock laboratory at Mont Terri. The added value for the 12 partners in terms of future experiments is threefold: (1) the Mont Terri project provides an international scientific platform of high reputation for research on radioactive waste disposal (= state-of-the-art research in argillaceous materials); (2) errors are explicitly allowed (= rock laboratory as a “playground” where experience is often gained through

  17. Teaching Literature as Dialogue: Coming to Terms with Terry Eagleton.

    Science.gov (United States)

    Madden, Thomas R.

    The literary theorist Terry Eagleton believes that literary study is the study of human discourse. To build on his idea for use in the classroom, it must first be assumed that literature constitutes a dialogue between the work (and its author) and the reader. The dialogue process can be introduced in a 2- to 4-week unit through a cluster of…

  18. Megan Terry's Plays for Youth at the Omaha Magic Theatre.

    Science.gov (United States)

    Klein, Jeanne

    Nebraska's Omaha Magic Theatre (OMT) and playwright Megan Terry are concerned with producing socially relevant, issue-oriented musical plays, focusing on young people and the adults who influence their emotional lives. OMT's "Theatre of Process" focuses upon the performing artist to develop and test ways to make theater more meaningful,…

  19. Supervisors interventioner ved parallelprocesser

    DEFF Research Database (Denmark)

    Jacobsen, Claus Haugaard

    2006-01-01

    Artiklen reflekterer over supervisors anvendelse af, holdning til og intervention ved parallelprocesser. Parallelprocesser betegner en række mere eller mindre forskellige fænomener, der alle har til fælles, at en relation eller et tema i det psykoterapeutiske forhold gentages i det supervisoriske...

  20. A Local Supervisor

    Science.gov (United States)

    Mutchler, James

    1974-01-01

    Direct supervision of teachers for agricultural programs in Ohio is moving from the State to the local level. The primary function of the local supervisor is to improve the instruction in programs for high school and adult students in the Vocational Education Planning District. Other duties vary according to local policies. (AG)

  1. Supervisand og supervisor

    DEFF Research Database (Denmark)

    Jacobsen, Claus Haugaard

    2007-01-01

    Kapitlet redegør for aspekter ved det komplekse forhold mellem supervisand og supervisor, og der anlægges en række forskellige perspektiver. Først beskrives forholdet fra supervisandens perspektiv. At indtræde i rollen som supervisand er, foruden at være lærerigt og fagligt udviklende, ofte også ...

  2. Supervisand og supervisor

    DEFF Research Database (Denmark)

    Jacobsen, Claus Haugaard

    2007-01-01

    Kapitlet redegør for aspekter ved det komplekse forhold mellem supervisand og supervisor, og der anlægges en række forskellige perspektiver. Først beskrives forholdet fra supervisandens perspektiv. At indtræde i rollen som supervisand er, foruden at være lærerigt og fagligt udviklende, ofte også ...

  3. Training facilitators and supervisors

    DEFF Research Database (Denmark)

    Kjær, Louise Binow; O Connor, Maja; Krogh, Kristian;

    At the Master’s program in Medicine at Aarhus University, Denmark, we have developed a faculty development program for facilitators and supervisors in 4 progressing student modules in communication, cooperation, and leadership. 1) A course for module 1 and 3 facilitators inspired by the apprentic...

  4. Novice supervisors' tasks and training

    DEFF Research Database (Denmark)

    Nielsen, Jan; Jacobsen, Claus Haugaard; Mathiesen, Birgit Bork

    2012-01-01

    were confronted with complicated jobs, e.g., group, internal and interdisciplinary supervision, but were not prepared, i.e. trained, prior to these tasks. These findings imply that more training is needed for novice supervisors. Preferably, this training should be introduced before, or at least...... parallel to, the first supervisor tasks, preparing the novice supervisors for the often complicated tasks they are meeting....

  5. 78 FR 7642 - Airworthiness Directives; Piper Aircraft, Inc.

    Science.gov (United States)

    2013-02-04

    ...-020-AD; Amendment 39-17334; AD 2013-02-13] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... airworthiness directive (AD) for certain Piper Aircraft, Inc. (type certificate previously held by The New Piper... information identified in this AD, contact Piper Aircraft, Inc., 2926 Piper Drive, Vero Beach, Florida...

  6. SINGLE PHASE ANALYTICAL MODELS FOR TERRY TURBINE NOZZLE

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Haihua; Zhang, Hongbin; Zou, Ling; O' Brien, James

    2016-11-01

    All BWR RCIC (Reactor Core Isolation Cooling) systems and PWR AFW (Auxiliary Feed Water) systems use Terry turbine, which is composed of the wheel with turbine buckets and several groups of fixed nozzles and reversing chambers inside the turbine casing. The inlet steam is accelerated through the turbine nozzle and impacts on the wheel buckets, generating work to drive the RCIC pump. As part of the efforts to understand the unexpected “self-regulating” mode of the RCIC systems in Fukushima accidents and extend BWR RCIC and PWR AFW operational range and flexibility, mechanistic models for the Terry turbine, based on Sandia National Laboratories’ original work, has been developed and implemented in the RELAP-7 code to simulate the RCIC system. RELAP-7 is a new reactor system code currently under development with the funding support from U.S. Department of Energy. The RELAP-7 code is a fully implicit code and the preconditioned Jacobian-free Newton-Krylov (JFNK) method is used to solve the discretized nonlinear system. This paper presents a set of analytical models for simulating the flow through the Terry turbine nozzles when inlet fluid is pure steam. The implementation of the models into RELAP-7 will be briefly discussed. In the Sandia model, the turbine bucket inlet velocity is provided according to a reduced-order model, which was obtained from a large number of CFD simulations. In this work, we propose an alternative method, using an under-expanded jet model to obtain the velocity and thermodynamic conditions for the turbine bucket inlet. The models include both adiabatic expansion process inside the nozzle and free expansion process out of the nozzle to reach the ambient pressure. The combined models are able to predict the steam mass flow rate and supersonic velocity to the Terry turbine bucket entrance, which are the necessary input conditions for the Terry Turbine rotor model. The nozzle analytical models were validated with experimental data and

  7. Citogenética de Piper hispidinervum e Piper aduncum Cytogenetics of Piper hispidinervum and Piper aduncum

    Directory of Open Access Journals (Sweden)

    Juliane Dornellas Nunes

    2007-07-01

    Full Text Available O objetivo deste trabalho foi detectar diferenças entre duas espécies de pimenta-longa por meio de análise de cariótipos. Foram analisados cinco acessos de Piper hispidinervum (Piperaceae C. DC. e Piper aduncum L. (Piperaceae pertencentes à coleção de germoplasma da Embrapa Acre, utilizando-se o método de esmagamento e coloração de Feulgen. As duas espécies apresentaram número cromossômico 2n = 24 e cromossomos pequenos e metacêntricos com comprimento médio de 1,38 µm em P. hispidinervum e 1,32 µm em P. aduncum. Pelos descritores citogenéticos obtidos não há diferença entre as duas espécies.The aim of this work was to detect differences between two species of long pepper by karyotypic analysis. Five acessions of Piper hispidinervum C. DC. (Piperaceae and Piper aduncum L. (Piperaceae, belonging to germplasm collection of Embrapa Acre, were analysed using squashing technique and Feulgen staining. The chromosome number observed for both species was 2n = 24 and karyotype presented small metacentric chromossomes, with average length of 1.38 µm in P. hispidinervum and 1.32 µm in P. aduncum. Karyotypic descriptions pointed out that the species are not different.

  8. Antifungal compounds from Piper species

    Science.gov (United States)

    Piper is a big genus of the plant family Piperaceae, with more than 700 species widely distributed in the tropical and subtropical regions of the world. Some species are used in folk medicine as analgesics, antiseptics, insecticides, and antimicrobials or for the treatment of toothache, haemorrhoid...

  9. 75 FR 82329 - Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper...

    Science.gov (United States)

    2010-12-30

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper Aircraft, Inc.) Models PA-46-310P, PA- 46-350P, and... certain Piper Aircraft, Inc. Models PA-46-310P and PA-46-350P airplanes that are equipped with a Lewis...

  10. 76 FR 18033 - Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper...

    Science.gov (United States)

    2011-04-01

    ...-060-AD; Amendment 39-16635; AD 2011-06-10] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper Aircraft, Inc.) Models PA-46-310P, PA- 46-350P, and...: We are superseding an existing airworthiness directive (AD) that applies to certain Piper...

  11. 77 FR 14316 - Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper...

    Science.gov (United States)

    2012-03-09

    .... (Type Certificate Previously Held by The New Piper Aircraft Inc.) Airplanes AGENCY: Federal Aviation... previously held by The New Piper Aircraft Inc.) Models PA-31T and PA- 31T1 airplanes. The existing AD... the Federal Register for certain Piper Aircraft, Inc. (type certificate previously held by The...

  12. KOMPOSISI KIMIA MINYAK ATSIRI BUAH SIRIH HIJAU (PIPER BETLE L, KEMUKUS (PIPER CUBEBA L DAN CABE JAWA (PIPER RETROFRACTUM VAHL

    Directory of Open Access Journals (Sweden)

    M. Widyo Wartono

    2014-05-01

    Full Text Available Tumbuhan genus Piper mempunyai kandungan minyak atsiri hampir disemua bagiannya, namun komposisi kimianya belum semua dilaporkan. Pada laporan ini kami melakukan isolasi dan identifikasi senyawa kimia minyak atsiri pada bagian buah tumbuhan Piper. Isolasi minyak atsiri buah Piper dilakukan dengan destilasi air menggunakan destilasi Stahl dan analisis komposisi kimia dengan kromatografi gas-spektroskopi masa (GC-MS. Kandungan minyak atsiri buah sirih hijau (Piper betle 1,4% (v/b, cabe jawa (Piper retrofractum 1% (v/b, dan buah kemukus (Piper cubeba 1,7% (v/b. Hasil analisis GC-MS menunjukan kandungan utama minyak atsiri adalah senyawa golongan monoterpen, seskuiterpen dan fenil propanoid. Kandungan utama minyak atsiri buah sirih hijau (P. betle adalah eugenol (12,36%, isokaryofillena (9,55% dan β-selinena (8,09%, sedangkan komponen utama buah cabe jawa (Piper retrofractum adalah isokaryofilen (8,88%, β-bisabolen (7,01% dan zingiberen (6,32%, dan minyak atsiri buah kemukus (Piper cubeba adalah spathulanol (27,05%, sativen (8,73% dan germakren D (7,50%.

  13. Assessment of Clinical Supervisor Competencies.

    Science.gov (United States)

    Getz, Hildy

    1999-01-01

    Presents a focus and process to assist those training clinical supervisors to assess competencies of the supervisor. States that process creates a practical framework that can be adapted for supervision competencies in other fields. Concludes that assessment methodology gives meaning to the support and structure vital at all levels of training…

  14. Efficient DNA barcode regions for classifying Piper species (Piperaceae).

    Science.gov (United States)

    Chaveerach, Arunrat; Tanee, Tawatchai; Sanubol, Arisa; Monkheang, Pansa; Sudmoon, Runglawan

    2016-01-01

    Piper species are used for spices, in traditional and processed forms of medicines, in cosmetic compounds, in cultural activities and insecticides. Here barcode analysis was performed for identification of plant parts, young plants and modified forms of plants. Thirty-six Piper species were collected and the three barcode regions, matK, rbcL and psbA-trnH spacer, were amplified, sequenced and aligned to determine their genetic distances. For intraspecific genetic distances, the most effective values for the species identification ranged from no difference to very low distance values. However, Piper betle had the highest values at 0.386 for the matK region. This finding may be due to Piper betle being an economic and cultivated species, and thus is supported with growth factors, which may have affected its genetic distance. The interspecific genetic distances that were most effective for identification of different species were from the matK region and ranged from a low of 0.002 in 27 paired species to a high of 0.486. Eight species pairs, Piper kraense and Piper dominantinervium, Piper magnibaccum and Piper kraense, Piper phuwuaense and Piper dominantinervium, Piper phuwuaense and Piper kraense, Piper pilobracteatum and Piper dominantinervium, Piper pilobracteatum and Piper kraense, Piper pilobracteatum and Piper phuwuaense and Piper sylvestre and Piper polysyphonum, that presented a genetic distance of 0.000 and were identified by independently using each of the other two regions. Concisely, these three barcode regions are powerful for further efficient identification of the 36 Piper species.

  15. Efficient DNA barcode regions for classifying Piper species (Piperaceae)

    Science.gov (United States)

    Chaveerach, Arunrat; Tanee, Tawatchai; Sanubol, Arisa; Monkheang, Pansa; Sudmoon, Runglawan

    2016-01-01

    Abstract Piper species are used for spices, in traditional and processed forms of medicines, in cosmetic compounds, in cultural activities and insecticides. Here barcode analysis was performed for identification of plant parts, young plants and modified forms of plants. Thirty-six Piper species were collected and the three barcode regions, matK, rbcL and psbA-trnH spacer, were amplified, sequenced and aligned to determine their genetic distances. For intraspecific genetic distances, the most effective values for the species identification ranged from no difference to very low distance values. However, Piper betle had the highest values at 0.386 for the matK region. This finding may be due to Piper betle being an economic and cultivated species, and thus is supported with growth factors, which may have affected its genetic distance. The interspecific genetic distances that were most effective for identification of different species were from the matK region and ranged from a low of 0.002 in 27 paired species to a high of 0.486. Eight species pairs, Piper kraense and Piper dominantinervium, Piper magnibaccum and Piper kraense, Piper phuwuaense and Piper dominantinervium, Piper phuwuaense and Piper kraense, Piper pilobracteatum and Piper dominantinervium, Piper pilobracteatum and Piper kraense, Piper pilobracteatum and Piper phuwuaense and Piper sylvestre and Piper polysyphonum, that presented a genetic distance of 0.000 and were identified by independently using each of the other two regions. Concisely, these three barcode regions are powerful for further efficient identification of the 36 Piper species. PMID:27829794

  16. 77 FR 42455 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2012-07-19

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... directive (AD) for all Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc... receive about this proposed AD. Discussion Three forced landings of Piper Aircraft, Inc. Model...

  17. 78 FR 41277 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-07-10

    ...-018-AD; Amendment 39-17489; AD 2013-13-01] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc.... SUMMARY: We are adopting a new airworthiness directive (AD) for certain Piper Aircraft, Inc. Models PA-46... information identified in this AD, contact Piper Aircraft, Inc., 2926 Piper Drive, Vero Beach, FL...

  18. 77 FR 57534 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2012-09-18

    ... TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper... all Piper Aircraft, Inc. Models PA-31, PA-31-325, and PA-31-350 airplanes. The existing AD currently... identified in this proposed AD, contact Piper Aircraft, Inc., 2926 Piper Drive, Vero Beach, Florida...

  19. 78 FR 35110 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-06-12

    ...-001-AD; Amendment 39-17457; AD 2013-10-04] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... superseding an existing airworthiness directive (AD) for all Piper Aircraft, Inc. Models PA-31, PA-31-325, and.... ADDRESSES: For service information identified in this AD, contact Piper Aircraft, Inc., 2926 Piper...

  20. 78 FR 76040 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-12-16

    ...-AD; Amendment 39-17691; AD 99-26-19 R1] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... Airworthiness Directive (AD) 99-26-19 that applies to certain The New Piper Aircraft, Inc. Model J-2 airplanes... identified in this AD, contact Piper Aircraft, Inc., Customer Services, 2926 Piper Drive, Vero Beach, Florida...

  1. 77 FR 45979 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2012-08-02

    ...] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc. Airplanes AGENCY: Federal Aviation... airworthiness directive (AD) for certain Piper Aircraft, Inc. (type certificate previously held by The New Piper... Federal holidays. For service information identified in this proposed AD, contact Piper Aircraft, Inc...

  2. PIPER: Primordial Inflation Polarization Explorer

    Science.gov (United States)

    Lazear, Justin; Ade, P.; Benford, D. J.; Bennett, C. L.; Chuss, D. T.; Dotson, J. L.; Eimer, J.; Fixsen, D. J.; Halpern, M.; Hinderks, J.; Hinshaw, G. F.; Irwin, K.; Jhabvala, C.; Johnson, B.; Kogut, A. J.; Mirel, P.; Moseley, S. H.; Staguhn, J.; Switzer, E.; Tucker, C. E.; Weston, A.; Wollack, E.

    2014-01-01

    The Primordial Inflation Polarization ExploreR (PIPER) is a balloon-borne cosmic microwave background (CMB) polarization experiment searching for large-angular scale B-mode polarization to constrain Inflation in the early universe. The Inflationary Big Bang theory predicts that the epoch of inflation will result in a background of gravitational waves. These gravitational waves imprinted their unique B-mode signature on the CMB polarization, two features of which are a peak at ell ~ 80 and a "bump" below ell ~ 10 in the B-mode angular power spectrum. The ell ~ 80 "recombination" peak is the first peak caused by gravitational waves imprinting tensor (B-mode) perturbations onto the CMB spectrum during recombination. Gravitational waves at larger scales have not yet entered the horizon and may not contribute, and at smaller scales have decayed away by other interactions, giving rise to a peak at horizon scale. The ell ~ 10 "reionization" bump is caused by a similar mechanism as the recombination peak, where gravitational waves imprint B-mode perturbations into the spectrum, now at larger horizon scales. PIPER will target the reionization bump while keeping enough angular resolution to measure the recombination peak, with sensitivity down to tensor-to-scalar ratio r = 0.007. A series of flights alternating between north and south will produce nearly full-sky temperature and polarization maps and measure the low-ell spectra. 5120 transition edge sensor (TES) bolometers each with 20 arcmin beamwidth, distributed into 4 rectangular close-packed arrays maintained at 150 mK will provide small-scale resolution and sensitivity. PIPER consists of two co-aligned telescopes, each with a front-end variable-delay polarization modulator rapidly modulating either the Q or U Stokes parameters to provide polarization sensitivity and mitigate systematic errors. To achieve background-limited sensitivity, the entire instrument is enclosed in an open bucket dewar maintained at 1.5 K. PIPER

  3. The Primordial Inflation Polarization Explorer (PIPER)

    Science.gov (United States)

    Gandilo, Natalie; Ade, Peter; Benford, Dominic J.; Bennett, Charles L.; Chuss, David T.; Dotson, Jessie L.; Eimer, Joseph; Fixsen, Dale J.; Halpern, Mark; Hilton, Gene; Hinshaw, Gary F.; Irwin, Kent; Jhabvala, Christine; Kimball, Mark; Kogut, Alan J.; Lowe, Luke; McMahon, Jeff; Miller, Timothy; Mirel, Paul; Moseley, Samuel H.; Pawlyk, Samuel; Rodriguez, Samelys; Sharp, Elmer; Shirron, Peter; Staguhn, Johannes; Sullivan, Dan; Switzer, Eric; Taraschi, Peter; tucker, carole; Wollack, Edward

    2017-01-01

    We present an overview of PIPER, the Primordial Inflation Polarization Explorer. PIPER is a balloon-borne telescope designed to map the large scale polarization of the Cosmic Microwave Background as well as the polarized emission from galactic dust at 200, 270, 350, and 600 GHz, with 21, 15, 14, and 14 arcminutes of angular resolution respectively. PIPER uses twin telescopes with Variable-delay Polarization Modulators to simultaneously map Stokes I, Q, U and V. Cold optics and the lack of a warm window allow the instrument to achieve background limited sensitivity. Over the course of 8 conventional balloon flights from the Northern and Southern hemisphere, PIPER will map 85% of the sky, measuring the B-mode polarization spectrum from the reionization bump to l~300, and placing an upper limit on the tensor-to-scalar ratio of rPIPER's first science flight will be in June 2017 from Palestine, Texas.

  4. Chemical constituents from Piper wallichii.

    Science.gov (United States)

    Shi, Yan-Ni; Yang, Lian; Zhao, Jin-Hua; Shi, Yi-Ming; Qu, Yan; Zhu, Hong-Tao; Wang, Dong; Yang, Chong-Ren; Li, Xing-Cong; Xu, Min; Zhang, Ying-Jun

    2015-01-01

    Fifteen known compounds including four triterpenoids (1-4), one sterol (5), one diketopiperazine alkaloid (6) and nine phenolics (7-15) were isolated from the stems of Piper wallichii. Their structures were elucidated by means of spectroscopic analysis, and acidic hydrolysis in case of the 2-oxo-3β,19α,23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (1). The structure of compound 1 was fully assigned by 1D and 2D NMR experiments for the first time. All isolates were tested for their antibacterial, antifungal, anti-inflammatory and antiplatelet aggregation bioactivities.

  5. Supervisor Attraction as a Function of Level of Supervisor Skillfulness and Supervisees' Perceived Similarity

    Science.gov (United States)

    Hester, Larry Ronald; And Others

    1976-01-01

    This laboratory analogue investigated the effects of supervisor skillfulness and supervisor-supervisee attitude similarity on the attraction of the supervisee to the supervisor. Results showed a main effect of supervisor skillfulness on attraction but did not show attraction to vary as a function of supervisor-supervisee attitude similarity.…

  6. Supervisor Attraction as a Function of Level of Supervisor Skillfulness and Supervisees' Perceived Similarity

    Science.gov (United States)

    Hester, Larry Ronald; And Others

    1976-01-01

    This laboratory analogue investigated the effects of supervisor skillfulness and supervisor-supervisee attitude similarity on the attraction of the supervisee to the supervisor. Results showed a main effect of supervisor skillfulness on attraction but did not show attraction to vary as a function of supervisor-supervisee attitude similarity.…

  7. Composition and antifungal activity of essential oils from Piper aduncum, Piper arboreum and Piper tuberculatum

    Directory of Open Access Journals (Sweden)

    Hosana M. Debonsi Navickiene

    2006-06-01

    Full Text Available The composition of essential oils from leaves, stems and fruits of Piper aduncum, P. arboreum and P. tuberculatum was examined by means of GC-MS and antifungal assay. There was a predominance of monoterpenes in P. aduncum and P. tuberculatum and of sesquiterpenes in P. arboreum. P. aduncum showed the richest essential oil composition, including linalool. The essential oils from fruits of P. aduncum and P. tuberculatum showed the highest antifungal activity with the MIC of 10 µg as determined against Cladosporium cladosporioides and C. sphaerospermum, respectively. This is the first report of the composition of essential oils from P. tuberculatum.

  8. Piper J-3L50 Cub

    Science.gov (United States)

    1942-01-01

    Piper J-3L50 Cub: The Piper J-3 Cub was evaluated at Langley by the NACA in late 1939 to early 1940. The J-3 was used by many World War II pilots as the airplane in which they were first introduced to flight. Note that the extended NACA use of the Cub led to its markings in NACA colors of yellow and blue, with the Committee's shield on the rudder.

  9. Terry Turbopump Expanded Operating Band Full-Scale Component and Basic Science Detailed Test Plan - Final.

    Energy Technology Data Exchange (ETDEWEB)

    Osborn, Douglas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Solom, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    This document details the milestone approach to define the true operating limitations (margins) of the Terry turbopump systems used in the nuclear industry for Milestone 3 (full-scale component experiments) and Milestone 4 (Terry turbopump basic science experiments) efforts. The overall multinational-sponsored program creates the technical basis to: (1) reduce and defer additional utility costs, (2) simplify plant operations, and (3) provide a better understanding of the true margin which could reduce overall risk of operations.

  10. Biopolitics, Terri Schiavo, and the sovereign subject of death.

    Science.gov (United States)

    Bishop, Jeffrey P

    2008-12-01

    Humanity does not gradually progress from combat to combat until it arrives at universal reciprocity, where the rule of law finally replaces warfare; humanity installs each of its violences in a system of rules and thus proceeds from domination to domination. (Foucault, 1984, 85) In this essay, I take a note from Michel Foucault regarding the notion of biopolitics. For Foucault, biopolitics has both repressive and constitutive properties. Foucault's claim is that with the rise of modern government, the state became exceedingly concerned about the body politic, the bodies that make up the polis, including the health of those bodies. However, Giorgio Agamben claims that Foucault and all western political philosophy misses the relationship between power and Sovereignty, with disastrous results and totalizing tendencies. I explore the case of Terri Schiavo claiming that the social conservatives have attempted to politicize bare life in its legal maneuverings, but I also show how the social liberals open an uncontrollable space between life and death. Both the left and the right miss the aporia at the heart of western political philosophy, and bioethics is complicit in the totalizing effects of contemporary medicine.

  11. PIPER Continuous Adiabatic Demagnetization Refrigerator

    Science.gov (United States)

    Kimball, Mark O.; Shirron, Peter J.; Canavan, Edgar R.; James, Bryan L.; Sampson, Michael A.; Letmate, Richard V.

    2017-01-01

    We report upon the development and testing of a 4-stage adiabatic demagnetization refrigerator (ADR) capable of continuous cooling at 0.100 Kelvin. This cooler is being built to cool the detector array aboard NASA's Primordial Inflation Polarization Explorer (PIPER) observatory. The goal of this balloon mission is to measure the primordial gravitational waves that should exist if the theory of cosmological inflation is correct. At altitude, the ADR will hold the array of transition-edge sensors at 100 mK continuously while periodically rejecting heat to a 1.2 K pumped helium bath. During testing on ground, the array is held at the same temperature but heat is rejected to a 4.2 K helium bath indicating the flexibility in this coolers design.

  12. Enzymatic and non-enzymatic antioxidants in selected Piper species.

    Science.gov (United States)

    Karthikeyan, J; Rani, P

    2003-02-01

    Piper species, commonly used in diet and traditional medicine were assessed for their antioxidant potential. Catalase activity was predominated in Piper longum, followed by Piper cubeba, green pepper, Piper brachystachyum and Piper nigrum. P. nigrum was richest in glutathione peroxidase and glucose-6-phosphate dehydrogenase, green pepper was richest in peroxidase and vitamin C while vitamin E was more in P. longum and P. nigrum. P. brachystachyum and P. longum were rich sources of vitamin A. All the Piper species had GSH content of around 1 to 2 nM/g tissue. The antioxidant components of Piper species constitute a very efficient system in scavenging a wide variety of reactive oxygen species. Antioxidant potential of Piper species was further confirmed by their ability to curtail in vitro lipid peroxidation by around 30-50% with concomitant increase in GSH content.

  13. Supervisor support: does supervisor support buffer or exacerbate the adverse effects of supervisor undermining?

    Science.gov (United States)

    Nahum-Shani, Inbal; Henderson, Melanie M; Lim, Sandy; Vinokur, Amiram D

    2014-05-01

    Empirical investigations concerning the interplay between supervisor support and supervisor undermining behaviors and their effects on employees yielded contradictory findings, with some studies suggesting that support buffers the adverse effects of undermining, and others suggesting that support exacerbates these adverse effects. Seeking to explain such contradictory findings, we integrate uncertainty-management perspectives with coping theory to posit that relational uncertainty is inherent in the mixture of supervisor support and undermining. Hence, whether supervisor support buffers or exacerbates the adverse effects of supervisor undermining on employee health and well-being depends on factors pertaining to employee ability to resolve and manage such relational uncertainty. Specifically, we hypothesize a buffering effect for employees with high self-esteem and high quality of work life, and an exacerbating effect for employees with low self-esteem and low quality of work life. Analyses of 2-wave data collected from a probability stratified sample of U.S. Air Force personnel supported our predictions. Two supplementary studies of the U.S. military replicated our core findings and demonstrated its practical significance. (c) 2014 APA, all rights reserved.

  14. 78 FR 54561 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-09-05

    ...-17457; AD 2013-10-04] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc. Airplanes AGENCY... an airworthiness directive (AD) that published in the Federal Register. That AD applies to all Piper... airplane exhaust system, and repair or replacement of parts as necessary for all Piper Aircraft,...

  15. 77 FR 31169 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2012-05-25

    ...-002-AD; Amendment 39-17058; AD 2012-10-09] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... superseding an existing airworthiness directive (AD) for certain Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc.) Models PA-31T and PA-31T1 airplanes. That AD...

  16. 78 FR 26556 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-05-07

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc...: This document withdraws a notice of proposed rulemaking (NPRM) that would have applied to all Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc.) Models PA-18 and...

  17. Training to Develop Savvy Supervisors.

    Science.gov (United States)

    Ramser, Charles D.; Forester, Douglas E.

    1989-01-01

    Many companies face problems when they change their hiring practices in order to meet their evolving needs. A three-phase supervisory training program can help reduce those problems and make supervisors more flexible and more effective. The phases are process theory and application, documentation and decision making, and supervisory…

  18. How to Cope with an Incompetent Supervisor.

    Science.gov (United States)

    White, Herbert S.

    1987-01-01

    Discusses the problem of incompetent library supervisors in terms of the process that results in the selection of such supervisors, inappropriate supervisory behaviors, and the effects on employees. Several strategies for coping with an incompetent supervisor are suggested. (4 references) (CLB)

  19. Pharmacognostical and Phytochemical study of Piper longum L. and Piper retrofractum Vahl.

    Directory of Open Access Journals (Sweden)

    Sharma Vinay

    2012-02-01

    Full Text Available Piperine, an alkaloid with diverse biological activity commonly occurring in fruits of Piper sp., has high commercial, economical, and medicinal value. In this study densitometric estimation of piperine from fruits of Piper longum L and Piper retrofractum Vahl.. It can be stated from this study that at industrial level P. longum Lin. is more suitable because of its preservation less and high percentage of Piperine(3.26µg/ml than P.retrofractum Vahl.(0.49µg/ml pharmacognostic and phytochemical characters of both species is discussed in present study.

  20. Molluscicidal effect of Piper guineense.

    Science.gov (United States)

    Ukwandu, N C D; Odaibo, A B; Okorie, T G; Nmorsi, O P G

    2011-01-01

    The study was undertaken to assess the dosage-mortality ratio and toxic effects of Piper guineense fruit extracts on the adults of Biomphalaria pfeifferi, the snail intermediate host of Schistosoma mansoni, which causes intestinal schistosomiasis. The result showed significant toxic effects with crude ethanol and hot water fruits extracts. The estimated lethal dose concentration by arithmetic method (LC(50) and LC(90)) using both crude ethanol and hot water fruit media extracts were found to be (0.10 ± 0.04, 0.9 ± 0.2) mgl(-1) respectively for ethanolic extract and (5.0 ± 1.4, 8.5 ± 0.7) mgl(-1) respectively for hot water extract. Ethanolic extract was more potent than hot water extract. An all or none phenomenon appeared characteristic of the biological activity of these extracts. There was significant decrease in oviposition rate (p < 0.02). The extract from the fruits of this tropical plant holds promise in the control of Biomphalaria pfeifferi.

  1. RP - HPLC Method for Determination of Piperine from Piper longum Linn. and Piper nigrum Linn

    OpenAIRE

    2005-01-01

    Piper longum Linn. and Piper nigrum Linn. are used as spices and medicines. Quantitative determination of piperine was undertaken to provide an easy and simple analytical method, which can be used as a routine quality control method. RP-HPLC was performed using methanol and water as mobile phase. The detection and quantification was performed at a wavelength of 345 nm. Linearity of detector response for piperine was between the concentrations 0.005% to 0.1%. The correlation coefficient obtai...

  2. Amides from Piper capense with CNS activity

    DEFF Research Database (Denmark)

    Pedersen, Mikael Egebjerg; Metzler, Bjørn; Stafford, Gary Ivan

    2009-01-01

    Piper capense L.f. (Piperaceae) is used traditionally in South Africa as a sleep inducing remedy. Bioassay-guided fractionation of the roots of P. capense led to the isolation of piperine (1) and 4,5-dihydropiperine (2), which showed moderate affinity for the benzodiazepine site on the GABA...

  3. The Primordial Inflation Polarization Explorer (PIPER)

    Science.gov (United States)

    Lazear, Justin Scott; Ade, Peter A.; Benford, Dominic J.; Bennett, Charles L.; Chuss, David T.; Dotson, Jessie L.; Eimer, Joseph R.; Fixsen, Dale J.; Halpern, Mark; Hinderks, James; Hinshaw, Gary F.; Irwin, Kent; Jhabvala, Christine; Johnson, Bradley; Kogut, Alan; Lowe, Luke; McMahon, Jeff J.; Miller, Timothy M.; Mirel, Paul; Moseley, S. Harvey; Rodriguez, Samelys; Staguhn, Johannes G.; Switzer, Eric R.; Tucker, Carole E.; Weston, Amy; Wollack, Edward

    2014-01-01

    The Primordial Inflation Polarization ExploreR (Piper) is a balloon-borne cosmic microwave background (CMB) polarimeter designed to search for evidence of inflation by measuring the large-angular scale CMB polarization signal. Bicep2 recently reported a detection of B-mode power corresponding to the tensor-to-scalar ratio r = 0.2 on approximately 2 degree scales. If the Bicep2 signal is caused by inflationary gravitational waves (IGWs), then there should be a corresponding increase in B-mode power on angular scales larger than 18 degrees. Piper is currently the only suborbital instrument capable of fully testing and extending the Bicep2 results by measuring the B-mode power spectrum on angular scales theta ? = approximately 0.6 deg to 90 deg, covering both the reionization bump and recombination peak, with sensitivity to measure the tensor-to-scalar ratio down to r = 0.007, and four frequency bands to distinguish foregrounds. Piper will accomplish this by mapping 85% of the sky in four frequency bands (200, 270, 350, 600 GHz) over a series of 8 conventional balloon flights from the northern and southern hemispheres. The instrument has background-limited sensitivity provided by fully cryogenic (1.5 K) optics focusing the sky signal onto four 32×40-pixel arrays of time-domain multiplexed Transition-Edge Sensor (TES) bolometers held at 140 milli-Kelvin. Polarization sensitivity and systematic control are provided by front-end Variabledelay Polarization Modulators (VPMs), which rapidly modulate only the polarized sky signal at 3 Hz and allow Piper to instantaneously measure the full Stokes vector (I,Q,U,0V) for each pointing. We describe the Piper instrument and progress towards its first flight.

  4. A Reflective Conversation with Terry Friedrichs on Teaching Academics to Gifted Students with Asperger Syndrome

    Science.gov (United States)

    Friedrichs, Terence Paul; Shaughnessy, Michael F.

    2015-01-01

    In this reflective interview with Terry Friedrichs--a hands-on academic-learning specialist and researcher with gifted students with Asperger Syndrome--he defines these pupils, describes their "straightforward" and confusing traits, and recounts his initial and later instructional experiences with them over several decades. The piece…

  5. A Reflective Conversation with Terry Friedrichs on Teaching Academics to Gifted Students with Asperger Syndrome

    Science.gov (United States)

    Friedrichs, Terence Paul; Shaughnessy, Michael F.

    2015-01-01

    In this reflective interview with Terry Friedrichs--a hands-on academic-learning specialist and researcher with gifted students with Asperger Syndrome--he defines these pupils, describes their "straightforward" and confusing traits, and recounts his initial and later instructional experiences with them over several decades. The piece…

  6. Extending the Shoreline of Wonder through the Research Attic of J. Terry Gates

    Science.gov (United States)

    Kuebel, Christa

    2017-01-01

    This article is a review of the Ohio Music Education Association Graduate Research Forum presentation from February 2017 in Cleveland. Each year, an expert in the field of music education is invited to the state conference to discuss research, practice, teaching, and learning. The presenter was Dr. J. Terry Gates of "The Hoenny Center for…

  7. Respirators: Supervisors Self-Study #43442

    Energy Technology Data Exchange (ETDEWEB)

    Chochoms, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-04-20

    This course, Respirators: Supervisors Self-Study (#43442), addresses training requirements for supervisors of respirator wearers as specified by the American National Standard Institute (ANSI) Standard for Respiratory Protection, ANSI Z88.2, and as incorporated by reference in the Department of Energy (DOE) Worker Health and Safety Rule, 10 Code of Federal Regulations (CFR) 851. This course also presents the responsibilities of supervisors of respirator wearers at Los Alamos National Laboratory (LANL).

  8. The NA48 trigger supervisor

    CERN Document Server

    Arcidiacono, R; Berotto, F; Bertolino, F; Govi, G; Menichetti, E; Sozzi, M

    2000-01-01

    The NA48 experiment aims to measure direct CP violation in the K/sub L//sup 0/ decays system with an accuracy of 2*10/sup -4/. High performances are required to the trigger and acquisition systems. This paper describes the NA48 Trigger Supervisor, a 40 MHz pipelined hardware system which correlates and processes trigger informations from local trigger sources, searching for interesting patterns. The trigger packet include a timestamp information used by the readout systems to retrieve detector data. The design architecture and functionality during 98 data taking are described. (5 refs).

  9. The Effect of Supervisor's Locus of Control and Employee Behavior on Supervisor Attributions.

    Science.gov (United States)

    Hillman, Maxine

    Two theoretical areas that lend themselves to study as they relate to supervisor-worker relations are locus of control and attribution theory. This study examined two general problems: (1) how a supervisor behaves toward an employee in relation to how that employee performs in the work place; and (2) how a supervisor's locus of control influences…

  10. Effect of Piper chaba Hunter, Piper sarmentosum Roxb. and Piper interruptum Opiz. on natural killer cell activity and lymphocyte proliferation.

    Science.gov (United States)

    Panthong, Sumalee; Itharat, Arunporn

    2014-08-01

    Immune system is the most important system ofhuman body. Thaifolk doctors have used some medicinal plants as an adaptogenic drug or immunomodulatory agent. Piper chaba Hunter, Piper sarmentosum Roxb. and Piper interruptum Opiz. are used by folk doctors to activate immune response in cancer patients. To investigate the effect on natural killer cell activity and on lymphocyte proliferation activity of water extract of P chaba Hunter P. sarmentosum Roxb. and P interruptum Opiz. MATERIAL ANDMETHOD: Plant materials were extracted by decoction method. All extracts were testedfor an immunomodulatory effect using PBMCs from twelve healthy donors by chromium release assay. Lymphocyte proliferation was also determined by 3H-thymidine uptake assay. The degree of activation was expressed as the stimulation index. The water extract of P chaba Hunter significantly increased lymphocyte proliferation at concentrations ofl ng/ml, 10 ng/ml, 1 μg/ml, 5 μg/ml, 10 μg/ml and 100 μg/ml. P sarmentosum Roxb., and P interruptum Opiz. extracts at those concentrations significantly stimulated lymphocyteproliferation. P sarmentosum Roxb. extractsignificantly increased natural killer (NK) cell activity at a concentration of 100 μg/ml but P chaba Hunter and P interruptum Opiz. extracts did not significantly stimulate natural killer cell activity. P chaba Hunter, P interruptum Opiz. andP sarmentosum Roxb. have an immunomodulatory effect especially for P sarmentosum Roxb. extract which can activate both lymphocyte proliferation and NK cell activity.

  11. The Forgotten Educator: Experiential Learning's Internship Supervisor

    Science.gov (United States)

    Sosland, Jeffrey K.; Lowenthal, Diane J.

    2017-01-01

    Past studies have addressed the role of the university, student interns and, the faculty advisor; here, we attempt to fill in a missing piece of the experiential-learning process by examining the role and importance of the often overlooked internship supervisor. A survey was developed and distributed to 343 recent internship supervisors. Their…

  12. Supervisor Development through Creative Approaches to Writing

    Science.gov (United States)

    Manathunga, Catherine; Peseta, Tai; McCormack, Coralie

    2010-01-01

    The development of research higher degree supervisors is a relatively recent phenomenon. In most cases, supervisor development continues within the traditional workshop mode and remains firmly located within what Bob Smith calls the "administrative framing" of supervision. This framing ensures that a liberal and policy-orientated discourse retains…

  13. The Forgotten Educator: Experiential Learning's Internship Supervisor

    Science.gov (United States)

    Sosland, Jeffrey K.; Lowenthal, Diane J.

    2017-01-01

    Past studies have addressed the role of the university, student interns and, the faculty advisor; here, we attempt to fill in a missing piece of the experiential-learning process by examining the role and importance of the often overlooked internship supervisor. A survey was developed and distributed to 343 recent internship supervisors. Their…

  14. FLAVONOIDES DE Piper glandulosissimum Yuncker (Piperaceae

    Directory of Open Access Journals (Sweden)

    Fabiano Pereira Santos

    2015-02-01

    Full Text Available Three flavanones, two chalcones and one dihydrochalcone were isolated from the branches of Piper glandulosissimum. All isolated compounds were characterized based on IR, UV, 1H and 13C NMR, including 2D NMR analyses (HMQC, HMBC, COSY and NOESY and comparison with the literature. The compound 7-hydroxy-5,8-dimethoxyflavanone displayed antimicrobial activity against Staphylococcus aureus, S. epidermidis, Trichophyton mentagrophytes and Microsporum canis.

  15. The Primordial Inflation Polarization Explorer (PIPER)

    CERN Document Server

    Gandilo, Natalie N; Benford, Dominic; Bennett, Charles L; Chuss, David T; Dotson, Jessie L; Eimer, Joseph R; Fixsen, Dale J; Halpern, Mark; Hilton, Gene; Hinshaw, Gary F; Irwin, Kent; Jhabvala, Christine; Kimball, Mark; Kogut, Alan; Lowe, Luke; McMahon, Jeff J; Miller, Timothy M; Mirel, Paul; Moseley, S Harvey; Pawlyk, Samuel; Rodriguez, Samelys; Sharp, Elmer; Shirron, Peter; Staguhn, Johannes G; Sullivan, Dan F; Switzer, Eric R; Taraschi, Peter; Tucker, Carole E; Wollack, Edward J

    2016-01-01

    The Primordial Inflation Polarization ExploreR (PIPER) is a balloon-borne telescope designed to measure the polarization of the Cosmic Microwave Background on large angular scales. PIPER will map 85% of the sky at 200, 270, 350, and 600 GHz over a series of 8 conventional balloon flights from the northern and southern hemispheres. The first science flight will use two 32x40 arrays of backshort-under-grid transition edge sensors, multiplexed in the time domain, and maintained at 100 mK by a Continuous Adiabatic Demagnetization Refrigerator. Front-end cryogenic Variable-delay Polarization Modulators provide systematic control by rotating linear to circular polarization at 3 Hz. Twin telescopes allow PIPER to measure Stokes I, Q, U, and V simultaneously. The telescope is maintained at 1.5 K in an LHe bucket dewar. Cold optics and the lack of a warm window permit sensitivity at the sky-background limit. The ultimate science target is a limit on the tensor-to-scalar ratio of r ~ 0.007, from the reionization bump t...

  16. The Primordial Inflation Polarization Explorer (PIPER)

    CERN Document Server

    Lazear, Justin; Benford, Dominic; Bennett, Charles L; Chuss, David T; Dotson, Jessie L; Eimer, Joseph R; Fixsen, Dale J; Halpern, Mark; Hilton, Gene; Hinderks, James; Hinshaw, Gary F; Irwin, Kent; Jhabvala, Christine; Johnson, Bradley; Kogut, Alan; Lowe, Luke; McMahon, Jeff J; Miller, Timothy M; Mirel, Paul; Moseley, S Harvey; Rodriguez, Samelys; Sharp, Elmer; Staguhn, Johannes G; Switzer, Eric R; Tucker, Carole E; Weston, Amy; Wollack, Edward J

    2014-01-01

    The Primordial Inflation Polarization Explorer (PIPER) is a balloon-borne cosmic microwave background (CMB) polarimeter designed to search for evidence of inflation by measuring the large-angular scale CMB polarization signal. BICEP2 recently reported a detection of B-mode power corresponding to the tensor-to-scalar ratio r = 0.2 on ~2 degree scales. If the BICEP2 signal is caused by inflationary gravitational waves (IGWs), then there should be a corresponding increase in B-mode power on angular scales larger than 18 degrees. PIPER is currently the only suborbital instrument capable of fully testing and extending the BICEP2 results by measuring the B-mode power spectrum on angular scales $\\theta$ = ~0.6 deg to 90 deg, covering both the reionization bump and recombination peak, with sensitivity to measure the tensor-to-scalar ratio down to r = 0.007, and four frequency bands to distinguish foregrounds. PIPER will accomplish this by mapping 85% of the sky in four frequency bands (200, 270, 350, 600 GHz) over a ...

  17. Piper nigrum, Piper betle and Gnetum gnemon Natural Food Sources with Anti-Quorum Sensing Properties

    OpenAIRE

    Li Ying Tan; Wai-Fong Yin; Kok-Gan Chan

    2013-01-01

    Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS) properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [pSB1075] and Chromobacterium violaceum CV026. It was found that the extracts of these three plants ha...

  18. 75 FR 61655 - Airworthiness Directives; Piper Aircraft, Inc. Model PA-28-161 Airplanes

    Science.gov (United States)

    2010-10-06

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... directive (AD) for all Piper Aircraft, Inc. (Piper) Model PA-28-161 airplanes equipped with Thielert.... Piper Model PA-28-161 airplanes modified by STC No. SA03303AT have a similar unsafe design feature that...

  19. 78 FR 49221 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-08-13

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc...). SUMMARY: We propose to revise airworthiness directive (AD) 99-26-19 that applies to certain The New Piper... Friday, except Federal holidays. For service information identified in this proposed AD, contact...

  20. Piper (Piperaceae) in the Philippine Islands: the climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2006-01-01

    Piper in the Philippine Islands is reviewed. Fifteen climbing species are recognized (many fewer than in previous treatments) and distinguished in a key. Most are widely distributed through Malesia, with ranges that end eastwards in the Solomon Islands or Australia. Piper myrmecophilum, the only tax

  1. Secondary metabolites from polar fractions of Piper umbellatum.

    Science.gov (United States)

    Tabopda, Turibio Kuiate; Mitaine-Offer, Anne-Claire; Miyamoto, Tomofumi; Tanaka, Chiaki; Ngadjuic, Bonaventure Tchaleu; Lacaille-Dubois, Marie-Aleth

    2012-05-01

    Seven known secondary metabolites were isolated from the methanol extract of the branches of Piper umbellatum. The identification of these compounds was mainly achieved by 2D NMR spectroscopic techniques and FAB-MS. Among them, the known cepharadiones A and B can be considered aschemotaxonomic markers of the genus Piper.

  2. 78 FR 56150 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

    Science.gov (United States)

    2013-09-12

    ...-018-AD; Amendment 39-17489; AD 2013-13-01] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc...-01 applies to certain Piper Aircraft, Inc. Models PA-46-310P, PA-46-350P, PA-46R-350T, and PA-46... modifying and eventually replacing the fuel vent valves if the nitrile parts are installed for certain...

  3. Three new species of Piper (Piperaceae) from the Guianas

    NARCIS (Netherlands)

    Görts-van Rijn, A.R.A.; Callejas Posada, R.

    2005-01-01

    Three new species of Piper from the Guianas and adjacent areas are described: Piper aulacospermum Callejas, P. ciliomarginatum Görts & Christenh. and P. remotinervium Görts. The differences between P. aulacospermum and P. bartlingianum (Miq.) C.DC., both belonging to subg. Ottonia, are given as well

  4. Piper (Piperaceae) in the Philippine Islands: the climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2006-01-01

    Piper in the Philippine Islands is reviewed. Fifteen climbing species are recognized (many fewer than in previous treatments) and distinguished in a key. Most are widely distributed through Malesia, with ranges that end eastwards in the Solomon Islands or Australia. Piper myrmecophilum, the only

  5. Three new species of Piper (Piperaceae) from the Guianas

    NARCIS (Netherlands)

    Görts-van Rijn, A.R.A.; Callejas Posada, R.

    2005-01-01

    Three new species of Piper from the Guianas and adjacent areas are described: Piper aulacospermum Callejas, P. ciliomarginatum Görts & Christenh. and P. remotinervium Görts. The differences between P. aulacospermum and P. bartlingianum (Miq.) C.DC., both belonging to subg. Ottonia, are given as well

  6. Piper (Piperaceae) in New Guinea: the climbing species

    OpenAIRE

    Gardner, R.O.

    2012-01-01

    Sixteen climbing Piper species are accepted for New Guinea. The three endemics, P. arfakianum, P. subcanirameum and P. versteegii, are fully described. Eight taxa of unclear circumscription are noted. A new variety of P. macropiper, endemic to Morobe Province of Papua New Guinea, is described. The presence of an ant-plant piper in West New Guinea is noted.

  7. GRS' research on clay rock in the Mont Terri underground laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Wieczorek, Klaus; Czaikowski, Oliver [Gesellschaft fuer Anlagen- und Reaktorsicherheit gGmbH, Braunschweig (Germany)

    2016-07-15

    For constructing a nuclear waste repository and for ensuring the safety requirements are met over very long time periods, thorough knowledge about the safety-relevant processes occurring in the coupled system of waste containers, engineered barriers, and the host rock is indispensable. For respectively targeted research work, the Mont Terri rock laboratory is a unique facility where repository research is performed in a clay rock environment. It is run by 16 international partners, and a great variety of questions are investigated. Some of the work which GRS as one of the Mont Terri partners is involved in is presented in this article. The focus is on thermal, hydraulic and mechanical behaviour of host rock and/or engineered barriers.

  8. Systemic testing on Bradley-Terry model against nonlinear ranking hierarchy.

    Science.gov (United States)

    Shev, Aaron; Fujii, Kevin; Hsieh, Fushing; McCowan, Brenda

    2014-01-01

    We take a system point of view toward constructing any power or ranking hierarchy onto a society of human or animal players. The most common hierarchy is the linear ranking, which is habitually used in nearly all real-world problems. A stronger version of linear ranking via increasing and unvarying winning potentials, known as Bradley-Terry model, is particularly popular. Only recently non-linear ranking hierarchy is discussed and developed through recognition of dominance information contents beyond direct dyadic win-and-loss. We take this development further by rigorously arguing for the necessity of accommodating system's global pattern information contents, and then introducing a systemic testing on Bradley-Terry model. Our test statistic with an ensemble based empirical distribution favorably compares with the Deviance test equipped with a Chi-squared asymptotic approximation. Several simulated and real data sets are analyzed throughout our development.

  9. The Terry Fox Research Institute’s Ontario Dialogue: how will personalized medicine change health care?

    OpenAIRE

    2011-01-01

    This is the final instalment in a series of three articles by the Terry Fox Research Institute about its pan-Canadian dialogue series, Cancer: Let’s Get Personal, a public research and outreach project undertaken in 2010. The dialogues served to launch a national and continuing conversation on personalized medicine with the medical and scientific communities and the public, including cancer survivors, patients, and caregivers. Participants at the Ontario dialogue, held in Toronto, October 18,...

  10. Ideas, Ideology, and Interests: On Terry Eagleton´s Approach to Culture

    Directory of Open Access Journals (Sweden)

    Olaf Miemiec

    2017-01-01

    Full Text Available The British literary theorist Terry Eagleton has significantly influenced contemporary debates on culture. This essay provides a reading of his book The Idea of Culture (2000, in which Eagleton discusses historical, philosophical and political contexts of notions of "culture" thereby unveiling the political interests inherent to such conceptual constructions. The essay highlights Eagleton's complex understanding of relations between nature and culture as well as his own materialist approach to culture.

  11. Regina v John Terry: The discursive construction of an alleged racist event

    OpenAIRE

    Gavins, J.; Simpson, P

    2015-01-01

    This article explores the conformation in discourse of a verbal exchange and its subsequent mediatised and legal ramifications. The event concerns an allegedly racist insult directed by high profile English professional footballer John Terry towards another player, Anton Ferdinand, during a televised match in October 2011. The substance of Terry’s utterance, which included the noun phrase ‘fucking black cunt’, was found by a Chief Magistrate not to be a racist insult, although the fact that t...

  12. Preliminary Two-Phase Terry Turbine Nozzle Models for RCIC Off-Design Operation Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Haihua [Idaho National Lab. (INL), Idaho Falls, ID (United States); O' Brien, James [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-06-12

    This report presents the effort to extend the single-phase analytical Terry turbine model to cover two-phase off-design conditions. The work includes: (1) adding well-established two-phase choking models – the Isentropic Homogenous Equilibrium Model (IHEM) and Moody’s model, and (2) theoretical development and implementation of a two-phase nozzle expansion model. The two choking models provide bounding cases for the two-phase choking mass flow rate. The new two-phase Terry turbine model uses the choking models to calculate the mass flow rate, the critical pressure at the nozzle throat, and steam quality. In the divergent stage, we only consider the vapor phase with a similar model for the single-phase case by assuming that the liquid phase would slip along the wall with a much slower speed and will not contribute the impulse on the rotor. We also modify the stagnation conditions according to two-phase choking conditions at the throat and the cross-section areas for steam flow at the nozzle throat and at the nozzle exit. The new two-phase Terry turbine model was benchmarked with the same steam nozzle test as for the single-phase model. Better agreement with the experimental data is observed than from the single-phase model. We also repeated the Terry turbine nozzle benchmark work against the Sandia CFD simulation results with the two-phase model for the pure steam inlet nozzle case. The RCIC start-up tests were simulated and compared with the single-phase model. Similar results are obtained. Finally, we designed a new RCIC system test case to simulate the self-regulated Terry turbine behavior observed in Fukushima accidents. In this test, a period inlet condition for the steam quality varying from 1 to 0 is applied. For the high quality inlet period, the RCIC system behaves just like the normal operation condition with a high pump injection flow rate and a nominal steam release rate through the turbine, with the net addition of water to the primary system; for

  13. Ombuds' Corner: Supervisor and supervisee

    CERN Multimedia

    Vincent Vuillemin

    2010-01-01

    Starting with this issue, the Bulletin introduces a new series of articles aiming to better explain the role of the Ombuds at CERN. We will publish practical examples of situations of potential misunderstanding that could have been resolved by the Ombuds if he had been contacted earlier. Please note that, in all the situations we present, the names are imaginary and used only to improve clarity.   John* and his supervisor Pat* have been working together for about four years, during which time they have had several disagreements and a few real explosions. They usually avoid each other for some time after each incident until things calm down again. During a meeting between them concerning objectives, the latent tension between them resulted in a fight during which John told Pat that she was mobbing him. Pat ended the meeting by throwing John out of her office. She said that she was no longer prepared to talk to him alone. John asked the Ombuds to facilitate the situation. When cont...

  14. The Primordial Inflation Polarization Explorer (PIPER)

    Science.gov (United States)

    Chuss, David T.; Ade, Peter A. R.; Benford, Dominic J.; Bennett, Charles L.; Dotson, Jessie L.; Eimer, Joseph R.; Fixsen, Dale J.; Halpern, Mark; Hilton, Gene; Hinderks, James; hide

    2010-01-01

    The Primordial Inflation Polarization Explorer (PIPER) is it balloon-borne instrument designed to search for the faint signature of inflation in the polarized component of the cosmic microwave background (C-N-113). Each flight will be configured for a single frequency, but in order to aid in the removal of the polarized foreground signal due to Galactic dust, the filters will be changed between flights. In this way, the CMB polarization at a total of four different frequencies (200, 270, 350, and 600 GHz) will be, measured on large angular scales. PIPER consists of a pair of cryogenic telescopes, one for measuring each of Stokes Q and U in the instrument frame. Each telescope receives both linear orthogonal polarizations in two 32 x 40 element planar arrays that utilize Transition-Edge Sensors (TES). The first element in each telescope is a variable-delay polarization modulator (VPM) that fully modulates the linear Stokes parameter to which the telescope is sensitive. There are several advantages to this architecture. First, by modulating at the front of the optics, instrumental polarization is unmodulated and is therefore cleanly separated from source polarization. Second, by implementing this system with the appropriate symmetry, systematic effects can be further mitigated. In the PIPER design, many of the. systematics are manifest in the unmeasured linear Stokes parameter for each telescope and this can be separated from the desired signal. Finally, the modulation cycle never mixes the Q and U linear Stokes parameters, and thus residuals in the modulation do not twist the observed polarization vector. This is advantageous because measuring the angle of linear polarization is critical for separating the inflationary signal from other polarized components.

  15. Cytotoxic and antibacterial dihydrochalcones from Piper aduncum.

    Science.gov (United States)

    Orjala, J; Wright, A D; Behrends, H; Folkers, G; Sticher, O; Rüegger, H; Rali, T

    1994-01-01

    Bioactivity-guided fractionation of a CH2Cl2 extract from the leaves of Piper aduncum afforded three new dihydrochalcones, piperaduncins A [3], B [4], and C [5], as well as two known dihydrochalcones, 2',6'-dihydroxy-4'-methoxydihydrochalcone [1] and 2',6',4-trihydroxy-4'-methoxydihydrochalcone [2] (asebogenin), together with sakuranetin, anodendroic acid methyl ester, and the carotenoid lutein. The structures of the isolates were elucidated by spectroscopic methods, mainly 1D- and 2D nmr spectroscopy. The proposed stereochemistry for compound 4 was deduced by NOESY spectroscopy and the corresponding energy minimum was established by molecular modelling calculations and translated into a 3D structure.

  16. Supervisor as Supervisee: Factors that Influence Doctoral Students' Self-Efficacy as Supervisors

    Science.gov (United States)

    Frick, Melodie Henson

    2009-01-01

    There have been many studies on supervising counselors-in-training; few researchers, however, have empirically examined the experiences of doctoral students as they train to become supervisors. More specifically, little is known about what factors influence the self-efficacy of doctoral students as supervisors-in-training while they work in the…

  17. Volatile Chemical Constituents of Piper aduncum L and Piper gibbilimbum C. DC (Piperaceae from Papua New Guinea

    Directory of Open Access Journals (Sweden)

    Peter G Waterman

    2007-03-01

    Full Text Available Exhaustive hydro-distillation of the leaves of Piper aduncum and fruits of Piper gibbilimbum (Piperaceae afforded colorless and pale orange colored oils in 0.35 and 0.30 % yields, respectively. Detailed chemical analysis by GC/MS indicated the volatile constituents of Piper aduncum to be composed of dill apiole (43.3 %, β-caryophyllene (8.2 %, piperitione (6.7 % and α-humulene (5.1 %, whilst the oil of P. gibbilimbum is dominated by the gibbilimbols A-D (74.2 %, with the remaining major constituents being the terpenes camphene (13.6 % and α-pinene (6.5 %.

  18. Volatile chemical constituents of Piper aduncum L and Piper gibbilimbum C. DC (Piperaceae) from Papua New Guinea.

    Science.gov (United States)

    Rali, Topul; Wossa, Stewart W; Leach, David N; Waterman, Peter G

    2007-03-09

    Exhaustive hydro-distillation of the leaves of Piper aduncum and fruits of Piper gibbilimbum (Piperaceae) afforded colorless and pale orange colored oils in 0.35 and 0.30 % yields, respectively. Detailed chemical analysis by GC/MS indicated the volatile constituents of Piper aduncum to be composed of dill apiole (43.3%), beta-caryophyllene (8.2%), piperitione (6.7%) and alpha-humulene (5.1%), whilst the oil of P. gibbilimbum is dominated by the gibbilimbols A-D (74.2%), with the remaining major constituents being the terpenes camphene (13.6%) and alpha-pinene (6.5%).

  19. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.

    Science.gov (United States)

    Shi, Yan-Ni; Liu, Fang-Fang; Jacob, Melissa R; Li, Xing-Cong; Zhu, Hong-Tao; Wang, Dong; Cheng, Rong-Rong; Yang, Chong-Ren; Xu, Min; Zhang, Ying-Jun

    2017-01-01

    Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-cinnamoyl-3- hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities. Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90 113 with IC50 values in the range between 4.7 and 20.0 µg/mL. Georg Thieme Verlag KG Stuttgart · New York.

  20. Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition.

    Science.gov (United States)

    Lee, Seung Woong; Kim, Young Kook; Kim, Koanhoi; Lee, Hyun Sun; Choi, Jung Ho; Lee, Woo Song; Jun, Chang-Duk; Park, Jee Hun; Lee, Jeong Min; Rho, Mun-Chual

    2008-08-15

    Eight alkamides 1-8 were isolated by bioassay-guided isolation of EtOH extracts of the fruits of Piper longum and Piper nigum (Piperaceae). Their structures were elucidated by spectroscopic analysis ((1)H, (13)C NMR, and ESI-MS) as follows: guineensine (1), retrofracamide C (2), (2E,4Z,8E)-N-[9-(3,4-methylenedioxyphenyl)-2,4,8-nonatrienoyl]piperidine (3), pipernonaline (4), piperrolein B (5), piperchabamide D (6), pellitorin (7), and dehydropipernonaline (8). Their compounds 3-5, 7, and 8 inhibited potently the direct binding between sICAM-1 and LFA-1 of THP-1 cells in a dose-dependent manner, with IC(50) values of 10.7, 8.8, 13.4, 13.5, and 6.0 microg/mL, respectively.

  1. Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum.

    Science.gov (United States)

    Lee, Seung Woong; Rho, Mun-Chual; Park, Hye Ran; Choi, Jung-Ho; Kang, Ji Yun; Lee, Jung Won; Kim, Koanhoi; Lee, Hyun Sun; Kim, Young Kook

    2006-12-27

    Pharmacological inhibition of acyl CoA:diacylglycerol acyltransferase (DGAT, EC 2.3.1.20) has emerged as a potential therapy for the treatment of obesity and type 2 diabetes. Bioassay-guided isolation of CHCl3 extracts of the fruits of Piper longum and Piper nigum (Piperaceae), using an in vitro DGAT inhibitory assay, lead to isolation of a new alkamide named (2E,4Z,8E)-N-[9-(3,4-methylenedioxyphenyl)-2,4,8-nonatrienoyl]piperidine (2), together with four known alkamides: retrofractamide C (1), pipernonaline (3), piperrolein B (4), and dehydropipernonaline (5). Compounds 2-5 inhibited DGAT with IC50 values of 29.8 (2), 37.2 (3), 20.1 (4), and 21.2 (5) microM, respectively, but the IC50 value for 1 was more than 900 microM. This finding indicates that compounds possessing piperidine groups (2-5) can be potential DGAT inhibitors.

  2. Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties

    Directory of Open Access Journals (Sweden)

    Li Ying Tan

    2013-03-01

    Full Text Available Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [pSB1075] and Chromobacterium violaceum CV026. It was found that the extracts of these three plants have anti-QS ability. Interestingly, the hexane, chloroform and methanol extracts from P. betle showed the most potent anti-QS activity as judged by the bioassays. Since there is a variety of plants that serve as food sources in Malaysia that have yet to be tested for anti-QS activity, future work should focus on identification of these plants and isolation of the anti-QS compounds.

  3. RP - HPLC Method for Determination of Piperine from Piper longum Linn. and Piper nigrum Linn

    Directory of Open Access Journals (Sweden)

    M. K. Santosh

    2005-01-01

    Full Text Available Piper longum Linn. and Piper nigrum Linn. are used as spices and medicines. Quantitative determination of piperine was undertaken to provide an easy and simple analytical method, which can be used as a routine quality control method. RP-HPLC was performed using methanol and water as mobile phase. The detection and quantification was performed at a wavelength of 345 nm. Linearity of detector response for piperine was between the concentrations 0.005% to 0.1%. The correlation coefficient obtained for the linearity was 0.998. The assay value of piperine for fruit and root of P. longum was found to be 0.879% and 0.31%. The assay value of piperine for fruit of P. nigrum was 4.5%. The recovery value of standard piperine was 99.4%. Low value of standard deviation and coefficient of variation are indicative of high precision of the method.

  4. Terri Schiavo: the assessment of the persistent vegetative state in accordance with German law.

    Science.gov (United States)

    Becker-Schwarze, Kathrin

    2005-12-01

    The case of Terri Schiavo in the USA served to intensify the debate in Germany which itself had in part already been characterised by fundamentalism. Now that some time has elapsed and the political debate has quietened, this case is to be taken up again in discussing the permissibility and the prerequisites of passive euthanasia for patients in a persistent vegetative state. A short reconstruction of the facts of the case (II) is to be followed by a survey of the case law of the Criminal Panels (III) which is essential to understand the present legal policy debate to be discussed at a later stage (IV).

  5. The Terry Fox Research Institute’s West Coast Dialogue: are we prepared for personalized medicine?

    OpenAIRE

    2010-01-01

    This meeting report is the second in a series by the Terry Fox Research Institute about its Pan-Canadian Dialogue Series on Cancer: Let’s Get Personal, a public research and outreach project. The inaugural dialogue was held in St. John’s, Newfoundland and Labrador, in April 2010 on the thirtieth anniversary of the Marathon of Hope. That dialogue launched a continuing conversation that the Institute is having with the Canadian public during 2010. This report summarizes the dialogue held at Sim...

  6. Flavonas, lignanas e terpeno de Piper umbellata (Piperaceae Flavones, lignans and terpene from Piper umbellata (Piperaceae

    Directory of Open Access Journals (Sweden)

    Debora Cristina Baldoqui

    2009-01-01

    Full Text Available The phytochemical investigation of Piper umbellata leaves yielded nine compounds including one terpenoid glucoside, five flavones (vitexin 2"-O-β-glucopyranoside, apigenin 8-C-β-D-glucopyranoside,orientin 8-C-β-D-glucopyranoside,5-hydroxy-7,3',4'-trimethoxy-flavone and velutin, two lignans (sesamin e dihydrocubebin and 4-nerolidylcathecol. Excepting 4-nerolidylcathecol, all compounds have not been described from this species yet.

  7. Flavones, lignans and terpene from Piper umbellata (Piperaceae); Flavonas, lignanas e terpeno de Piper umbellata (Piperaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Baldoqui, Debora Cristina; Bolzani, Vanderlan da S.; Furlan, Maysa [UNESP, Araraquara, SP (Brazil). Inst. de Quimica], e-mail: maysaf@iq.unesp.br; Kato, Massuo J. [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Quimica; Marques, Marcia O.M. [Instituto Agronomico de Campinas, SP (Brazil)

    2009-07-01

    The phytochemical investigation of Piper umbellata leaves yielded nine compounds including one terpenoid glucoside, five flavones (vitexin 2{sup -}O-{beta}-glucopyranoside, apigenin 8-C-{beta}-D-glucopyranoside, orientin 8-C-{beta}-D-glucopyranoside,5-hydroxy-7,3',4'-trimethoxy-flavone and velutin), two lignans (sesamin and dihydrocubebin) and 4-nerolidylcathecol. Excepting 4-nerolidylcathecol, all compounds have not been described from this species yet (author)

  8. PHYTOCHEMICAL AND THERAPEUTIC POTENTIAL OF PIPER LONGUM LINN A REVIEW

    Directory of Open Access Journals (Sweden)

    Chauhan Khushbu

    2011-02-01

    Full Text Available Medicinal plants have shown tremendous potential for the development of the new drug molecules for various serious diseases. Many plant derived products have found to play an important role in various disease conditions. Piper longum Linn. is a native of the Indo-Malaya region, belongs to family Piperaceae. Piper longum Linn. (Piperaceae has been used as a therapeutic agent in the treatment of various pathological conditions. The tribal population uses the plant for cardiovascular activities, anti-inflammatory activity and as a spice. Alkaloids, Lignans and volatile oil are reported in this plant. Extract of Piper longum fruits have been shown to posses various activities like Bio-availibity enhancer, immunomodulatory effect, antiasthamatic and hepatoprotective activity. In the present review an attempt has been made to explore different aspects of Piper longum.

  9. Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri

    Energy Technology Data Exchange (ETDEWEB)

    Houseworth, Jim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rutqvist, Jonny [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Asahina, Daisuke [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Chen, Fei [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Vilarrasa, Victor [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Liu, Hui-Hai [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Birkholzer, Jens [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-11-01

    Nuclear waste programs outside of the US have focused on different host rock types for geological disposal of high-level radioactive waste. Several countries, including France, Switzerland, Belgium, and Japan are exploring the possibility of waste disposal in shale and other clay-rich rock that fall within the general classification of argillaceous rock. This rock type is also of interest for the US program because the US has extensive sedimentary basins containing large deposits of argillaceous rock. LBNL, as part of the DOE-NE Used Fuel Disposition Campaign, is collaborating on some of the underground research laboratory (URL) activities at the Mont Terri URL near Saint-Ursanne, Switzerland. The Mont Terri project, which began in 1995, has developed a URL at a depth of about 300 m in a stiff clay formation called the Opalinus Clay. Our current collaboration efforts include two test modeling activities for the FE heater test and the HG-A leak-off test. This report documents results concerning our current modeling of these field tests. The overall objectives of these activities include an improved understanding of and advanced relevant modeling capabilities for EDZ evolution in clay repositories and the associated coupled processes, and to develop a technical basis for the maximum allowable temperature for a clay repository.

  10. Conference on Stochastic Analysis and Applications 2014 : in honour of Terry Lyons

    CERN Document Server

    Hambly, Ben; Zariphopoulou, Thaleia

    2014-01-01

    Articles from many of the main contributors to recent progress in stochastic analysis are included in this volume, which provides a snapshot of the current state of the area and its ongoing developments. It constitutes the proceedings of the conference on "Stochastic Analysis and Applications" held at the University of Oxford and the Oxford-Man Institute during 23-27 September, 2013. The conference honored the 60th birthday of Professor Terry Lyons FLSW FRSE FRS, Wallis Professor of Mathematics, University of Oxford. Terry Lyons is one of the leaders in the field of stochastic analysis. His introduction of the notion of rough paths has revolutionized the field, both in theory and in practice.  Stochastic Analysis is the branch of mathematics that deals with the analysis of dynamical systems affected by noise. It emerged as a core area of mathematics in the late 20th century and has subsequently developed into an important theory with a wide range of powerful and novel tools, and with impressive applications ...

  11. Teams ranking of Malaysia Super League using Bayesian expectation maximization for Generalized Bradley Terry Model

    Science.gov (United States)

    Nor, Shahdiba Binti Md; Mahmud, Zamalia

    2016-10-01

    The analysis of sports data has always aroused great interest among statisticians and sports data have been investigated from different perspectives often aim at forecasting the results. The study focuses on the 12 teams who join the Malaysian Super League (MSL) for season 2015. This paper used Bayesian Expectation Maximization for Generalized Bradley Terry Model to estimate all the football team's rankings. The Generalized Bradley-Terry model is possible to find the maximum likelihood (ML) estimate of the skill ratings λ using a simple iterative procedure. In order to maximize the function of ML, we need inferential bayesian method to get posterior distribution which can be computed quickly. The team's ability was estimated based on the previous year's game results by calculating the probability of winning based on the final scores for each team. It was found that model with tie scores does make a difference in affect the model of estimating the football team's ability in winning the next match. However, team with better results in the previous year has a better chance for scoring in the next game.

  12. 双层毛巾织物的设计%Design of Double Terry Towel

    Institute of Scientific and Technical Information of China (English)

    田琳

    2001-01-01

    双层毛巾的表层是毛巾组织织物,里层为平布,在织机上同时织出两层。上下两层可以分离,也可以连接在一起。产品既保持了毛巾织物的特点,又减少了抽毛几率,提高了舒适性。提出在设计双层毛巾织物时应考虑的问题以及在织造过程中的工艺设计要点%The face weave of double towel was terry structure, and the back weave was plain. The two layers of fabric were produced simultaneously in a loom,which were either detached each other or joined together. The characteristics of terry were remained in this type of fasric,whereas, the dislocation probability was decreased and eomfortability was increased. This paper pointed out some considerable questions on designing double towel cloth, and processing design keys of weaving

  13. Toxicidade de óleos essenciais de Piper aduncum e Piper hispidinervum em Sitophilus zeamais Toxicity of essential oils of Piper aduncum and Piper hispidinervum against Sitophilus zeamais

    Directory of Open Access Journals (Sweden)

    Joelma Lima Vidal Estrela

    2006-02-01

    Full Text Available Óleos essenciais de Piper aduncum L. e Piper hispidinervum C.DC. (Piperaceae foram avaliados quanto ao efeito inseticida em Sitophilus zeamais Motsch. por ação de contato, fumigação e tópica. Na determinação da DL50 e CL50, foi utilizada a análise de Probit. Médias porcentuais de mortalidade dos insetos foram comparadas por meio da análise de regressão linear e superposição das barras do erro padrão. S. zeamais foi mais suscetível ao efeito de contato do óleo de P. hispidinervum em relação ao de P. aduncum, obtendo-se CL50 de 0,51 e 2,87 mL cm- 2 de óleo, respectivamente. Mortalidade próxima a 100% foi obtida nas concentrações de 20 e 30% do óleo de P. hispidinervum. Quanto ao efeito fumigante, a susceptibilidade foi maior no óleo de P. aduncum do que no de P. hispidinervum. Houve diferença significativa entre os óleos somente nas concentrações de 0,1 e 1,0. A DL50 foi semelhante nos dois óleos essenciais por aplicação tópica. No entanto, a mortalidade foi maior com P. aduncum. Óleos essenciais de P. aduncum e P. hispidinervum possuem efeito inseticida em S. zeamais, mas as respostas dependem da concentração e do método de exposição a que o inseto seja submetido.Essential oils of Piper aduncum L. and Piper hispidinervum C. DC. (Piperaceae were tested against Sitophilus zeamais Motsch. Contact, fumigant toxicity and topical effect were tested. Probit analysis was employed in evaluating the LC50 and LD50 response. Linear regression analysis and superposition of the bars (means error standard were used for comparison of means percentage mortality. S. zeamais was more susceptible to the contact toxicity of the P. hispidinervum oil than P. aduncum oil with LC50 values of 0.51 and 2.87 mL cm-2 of the oil, respectively. The mortality rate was nearly 100% at P. hispidinervum oil concentrations of 20 and 30%. With respect to the fumigant action, the weevil was more susceptible to the P. aduncum oil than to P

  14. Piper nigrum and piperine: an update.

    Science.gov (United States)

    Meghwal, Murlidhar; Goswami, T K

    2013-08-01

    Black pepper (Piper nigrum L.) is a very widely used spice, known for its pungent constituent piperine. However, in addition to its culinary uses, pepper has important medicinal and preservative properties, and, more recently, piperine has been shown to have fundamental effects on p-glycoprotein and many enzyme systems, leading to biotransformative effects including chemoprevention, detoxification, and enhancement of the absorption and bioavailability of herbal and conventional drugs. Based on modern cell, animal, and human studies, piperine has been found to have immunomodulatory, anti-oxidant, anti-asthmatic, anti-carcinogenic, anti-inflammatory, anti-ulcer, and anti-amoebic properties. In this review, the chemical constituents, biological activities, effects of processing, and future potential of black pepper and piperine have been discussed thoroughly.

  15. [Identification of some Piper crude drugs based on Fourier transform infrared spectrometry].

    Science.gov (United States)

    Zhou, Ye; Zhang, Qing-Wei; Luo, Xue-Jun; Li, Pei-Fu; Song, Heng; Zhang, Bo-Li

    2014-09-01

    The common peak ratio and variant peak ratio were calculated by FTIR spectroscopy of seven medicinal plants of Piper. The dual index sequence of common peak ratio and variant peak ratio was established, which showed the sibship of the medicinal plants. The common peak ratio of Piper kadsura (Choisy) Ohwi, Piper wallichii (Miq.) Hand.-Mazz. Piper laetispicum (C. DC.) was greater than 77%, and the variant peak ratio was less than 30%. The results showed the near sibship between the three drugs. The common peak ratio of Piper kadsura (Choisy) Ohwi, Piper nigrum L. and Piper boehmeriae folium Wall (Miq.) C. DC. Var. tonkinense (C. DC.) was about 61% which showed the farther sibship. The common peak ratio of Piper kadsura (Choisy) Ohwi and Piper betle (Linn.) was only 44%, which showed the farthest sibship. Piper kadsura (choisy) Ohwi and its adulterants, such as Piper wallichii (Miq.) Hand. -Mazz., Piper boehmeriaefolium Wall (Miq.) C. DC. Var. tonkinense C. DC. , Piper laetispicum C. DC., Piper nigrum L., could be identified by comparing their second order derivative IR spectrum of the samples. FTIR technique is a non-destructive analysis method which provides information of functional group, type and hydrogen bond without complex pretreatment procedures such as extraction and separatioin. FTIR method has some characteristics such as rapid and simple analysis procedure, good reproducibility, non-destructive testing, few amount of required sample and low cost and is environment-friendly. The method solved the problems of limit in resource of Piper kadsura (Choisy) Ohwi, many fakes and difficulties in identification, and brought the security for the clinical medication. FTIR provides a new method for identification of Piper kadsura (choisy) Ohwi and its fakes and meets the requirement for comprehensive analy sis and global analysis of traditional Chinese medicine.

  16. The pharmacy supervisor and the employee pharmacist's job satisfaction.

    Science.gov (United States)

    North, M A; Kirk, K W

    1990-05-01

    It seems obvious that satisfaction with one's immediate supervisor would have a significant impact on one's general job satisfaction. However, this relationship has received little attention in the pharmacy literature. This study was designed to determine 1) whether there are differences in job-related satisfaction between pharmacists whose immediate supervisors are pharmacists and those whose supervisors are not pharmacists, and 2) whether the occurrence of conflict between a pharmacist and his or her immediate supervisor is related to the employee pharmacist's job and career satisfaction. The most pronounced finding was the importance of supervisors being pharmacists: satisfaction on five of six satisfaction subscales was related to whether one's supervisor was a pharmacist. Moreover, pharmacists who had the fewest conflicts and disagreements with their supervisors were more satisfied with their choice of pharmacy as a career, their employers, their supervisors, and their jobs.

  17. A new species and three taxonomic changes in Piper (Piperaceae) from Thailand

    NARCIS (Netherlands)

    Suwanphakdee, C.; Chantaranothai, P.

    2011-01-01

    A new species, Piper chiangdaoense from Doi Chiangdao Wildlife Sanctuary, Chiang Mai province, Thailand, is described and illustrated. Piper trichostigma is raised to specific status and an epitype is selected. Piper maculaphyllum and P. rubroglandulosum are reduced to the synonymy of P. argyrites a

  18. A new species and three taxonomic changes in Piper (Piperaceae) from Thailand

    NARCIS (Netherlands)

    Suwanphakdee, C.; Chantaranothai, P.

    2011-01-01

    A new species, Piper chiangdaoense from Doi Chiangdao Wildlife Sanctuary, Chiang Mai province, Thailand, is described and illustrated. Piper trichostigma is raised to specific status and an epitype is selected. Piper maculaphyllum and P. rubroglandulosum are reduced to the synonymy of P. argyrites

  19. The Role of the TP TESL Supervisor.

    Science.gov (United States)

    Bourke, James Mannes

    2001-01-01

    Examines the changing role of the student teacher supervisor in elementary school English as a Second Language education, arguing for a development model of supervision. Data collected over 6 years in Brunei indicated that there were tensions over different models of student teacher supervision used. The key functions of the student teacher…

  20. Roles, responsabilities and situations faced by supervisor

    Directory of Open Access Journals (Sweden)

    Bianca VLASA

    2010-04-01

    Full Text Available Supervision is a dinamic proces which includes changes, acquisitions which have as a result the improving of work conditions, the rise of eficiency, the satisfactions of the employees and the avoiding of professional exhaustion. Nowadays, supervisors are permanently challenged with continuous transformations. The success criteria of the leaders is no longer their capacity to manage teams and unexpected situations, but their real capacity to anticipate and guide their actions. A supervisor does not have the power to fire or hire employees, but he can recommend this to the superior level of management. However, the supervisor can have the following roles: guide, mentor, attorney (for organisation, atorney (for employees. One of the supervisor’s responsabilities is the organisation of the department, but he also has to revise employee’s needs, to set performance standards, to ensure that employees follow the politics, the confidentiality and the procedures of the organisation. Although the purpose to help the employee become efficient seems simple, it can become a frustrating experience. One study about stress factors among supervisors revealed that they confrunt with two kind of problems: their status and the pressure at the work place which affects their performance.

  1. The Evaluation Supervisor as Internal Auditor.

    Science.gov (United States)

    Farber, Irvin J.

    The role of the evaluation supervisor as internal auditor and his or her responsibility for assuring the independence and objectivity of evaluation results are discussed. Four sources of compromise of objectivity are discussed: factual, political, involvement, and affective. The first two sources of compromise cannot be accepted, A code of ethical…

  2. Training Supervisors in Employee Performance Appraisals.

    Science.gov (United States)

    Sims, Ronald R.

    1988-01-01

    The author presents a training program for supervisors designed to improve an organization's performance appraisal system. Legal issues surrounding performance appraisal are discussed. Course topics include (1) definition and purpose of performance appraisal, (2) how appraisals can improve performance, (3) negative reactions and how to overcome…

  3. Novice supervisors' tasks and training - a descriptive study

    DEFF Research Database (Denmark)

    Nielsen, Jan; Jacobsen, Claus H.; Mathiesen, Birgit Bork

    , i.e. trained, prior to these tasks. These findings imply that more training is needed for novice supervisors. Preferably, this training should be introduced before, or at least parallel to, the first supervisor tasks, preparing the novice supervisors for the often complicated tasks they are meeting....

  4. A Model for the Supervisor-Doctoral Student Relationship

    Science.gov (United States)

    Mainhard, Tim; van der Rijst, Roeland; van Tartwijk, Jan; Wubbels, Theo

    2009-01-01

    The supervisor-doctoral student interpersonal relationship is important for the success of a PhD-project. Therefore, information about doctoral students' perceptions of their relationship with their supervisor can be useful for providing detailed feedback to supervisors aiming at improving the quality of their supervision. This paper describes the…

  5. 7 CFR 58.53 - Supervisor of packaging required.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Supervisor of packaging required. 58.53 Section 58.53... Packaging Products with Official Identification § 58.53 Supervisor of packaging required. The official....54 through 58.57, shall be done only under the supervision of a supervisor of packaging....

  6. 46 CFR 197.210 - Designation of diving supervisor.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Designation of diving supervisor. 197.210 Section 197... HEALTH STANDARDS GENERAL PROVISIONS Commercial Diving Operations General § 197.210 Designation of diving supervisor. The name of the diving supervisor for each commercial diving operation shall be— (a)...

  7. 46 CFR 197.404 - Responsibilities of the diving supervisor.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Responsibilities of the diving supervisor. 197.404... SAFETY AND HEALTH STANDARDS GENERAL PROVISIONS Commercial Diving Operations Operations § 197.404 Responsibilities of the diving supervisor. (a) The diving supervisor shall— (1) Be fully cognizant of...

  8. Endorsement for Licensure: Practices and Challenges Reported by Counselor Supervisors

    Science.gov (United States)

    Miller, Cynthia M.

    2010-01-01

    The purpose of this mixed-method study was to explore the extent to which supervisors of post-matriculation, pre-licensed counselors engage in gatekeeping. Two-hundred seventy-nine supervisors of post-matriculation, pre-licensed counselors completed an online survey that assessed (1) what methods of supervision supervisors of post-matriculation,…

  9. 42 CFR 493.1469 - Standard: Cytology general supervisor qualifications.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Cytology general supervisor... Nonwaived Testing Laboratories Performing High Complexity Testing § 493.1469 Standard: Cytology general supervisor qualifications. The cytology general supervisor must be qualified to supervise cytology services...

  10. 42 CFR 493.1471 - Standard: Cytology general supervisor responsibilities.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Cytology general supervisor... Nonwaived Testing Laboratories Performing High Complexity Testing § 493.1471 Standard: Cytology general supervisor responsibilities. The technical supervisor of cytology may perform the duties of the cytology...

  11. Microstructure and porosity of Opalinus Clay at the Mont Terri rock laboratory (Switzerland)

    Science.gov (United States)

    Houben, M. E.; Laurich, B.; Desbois, G.; Urai, J. L.

    2012-04-01

    The Mont Terri rock laboratory (Canton Jura, Switzerland) is an international scientific platform of research on radioactive waste disposal in Opalinus Clay and results provide input for assessing the feasibility and safety of deep geological disposal of radioactive waste in argillaceous formations [1]. A main safety issue is to accurately investigate mass transport rates. To date several methods analyzed bulk permeability and porosity of Opalinus Clay. However, detailed quantitative investigation of microstructure and pore morphology is necessary to understand sealing capacity, coupled flow, capillary processes and associated deformation. To produce high quality cross-sections without microstructural damage that enable investigation of microstructure and porosity down the nm scale a combination of Broad Ion Beam (BIB) milling and SEM imaging has been used [2]. This method allowed direct imaging of the clay fabric and porosity on ca. 1 mm2 areas. The lateral variability of Opalinus Clay is low on the regional scale [1], whereas vertically the Opalinus Clay can be subdivided into six different lithological subfacies [3] based on variable silt layers, sandstone layers and siderite concretions present, where the end-members are the Shaly and Sandy facies. In this contribution microstructures and pore space in Opalinus Clay from the undisturbed Shaly and Sandy facies are studied and compared to disturbed samples from the "Main fault" within the Mont Terri rock laboratory. The Shaly facies in the lower half of the sequence constitutes of dark grey silty calcerous shales and argillaceous marls, whereas the Sandy facies comprises silty to sandy marls with sandstone lenses cemented with carbonate [3]. The qualitative mineralogical composition of all Opalinus Clay facies is similar, whereas the "Main Fault" shows calcite, celestite and pyrite veins. Although the overall microfabric differs per layer and per facies we observe low variability of microstructure and porosity in

  12. Geological modeling of a fault zone in clay rocks at the Mont-Terri laboratory (Switzerland)

    Science.gov (United States)

    Kakurina, M.; Guglielmi, Y.; Nussbaum, C.; Valley, B.

    2016-12-01

    Clay-rich formations are considered to be a natural barrier for radionuclides or fluids (water, hydrocarbons, CO2) migration. However, little is known about the architecture of faults affecting clay formations because of their quick alteration at the Earth's surface. The Mont Terri Underground Research Laboratory provides exceptional conditions to investigate an un-weathered, perfectly exposed clay fault zone architecture and to conduct fault activation experiments that allow explore the conditions for stability of such clay faults. Here we show first results from a detailed geological model of the Mont Terri Main Fault architecture, using GoCad software, a detailed structural analysis of 6 fully cored and logged 30-to-50m long and 3-to-15m spaced boreholes crossing the fault zone. These high-definition geological data were acquired within the Fault Slip (FS) experiment project that consisted in fluid injections in different intervals within the fault using the SIMFIP probe to explore the conditions for the fault mechanical and seismic stability. The Mont Terri Main Fault "core" consists of a thrust zone about 0.8 to 3m wide that is bounded by two major fault planes. Between these planes, there is an assembly of distinct slickensided surfaces and various facies including scaly clays, fault gouge and fractured zones. Scaly clay including S-C bands and microfolds occurs in larger zones at top and bottom of the Mail Fault. A cm-thin layer of gouge, that is known to accommodate high strain parts, runs along the upper fault zone boundary. The non-scaly part mainly consists of undeformed rock block, bounded by slickensides. Such a complexity as well as the continuity of the two major surfaces are hard to correlate between the different boreholes even with the high density of geological data within the relatively small volume of the experiment. This may show that a poor strain localization occurred during faulting giving some perspectives about the potential for

  13. "We Cooperate, or We Die": Sustainable Coexistence in Terry Pratchett's "The Amazing Maurice" and "His Educated Rodents"

    Science.gov (United States)

    Oziewicz, Marek

    2009-01-01

    This article examines Terry Pratchett's "The Amazing Maurice" as a modern example of environmentally informed social dreaming about sustainable coexistence. In our increasingly ecologically-conscious world sustainability and coexistence have become key words in the discourse about social, economic and political relations. The problem of relating…

  14. Development and Implementation of Mechanistic Terry Turbine Models in RELAP-7 to Simulate RCIC Normal Operation Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Haihua [Idaho National Lab. (INL), Idaho Falls, ID (United States); Zou, Ling [Idaho National Lab. (INL), Idaho Falls, ID (United States); Zhang, Hongbin [Idaho National Lab. (INL), Idaho Falls, ID (United States); O' Brien, James Edward [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    As part of the efforts to understand the unexpected “self-regulating” mode of the RCIC (Reactor Core Isolation Cooling) systems in Fukushima accidents and extend BWR RCIC and PWR AFW (Auxiliary Feed Water) operational range and flexibility, mechanistic models for the Terry turbine, based on Sandia’s original work [1], have been developed and implemented in the RELAP-7 code to simulate the RCIC system. In 2016, our effort has been focused on normal working conditions of the RCIC system. More complex off-design conditions will be pursued in later years when more data are available. In the Sandia model, the turbine stator inlet velocity is provided according to a reduced-order model which was obtained from a large number of CFD (computational fluid dynamics) simulations. In this work, we propose an alternative method, using an under-expanded jet model to obtain the velocity and thermodynamic conditions for the turbine stator inlet. The models include both an adiabatic expansion process inside the nozzle and a free expansion process outside of the nozzle to ambient pressure. The combined models are able to predict the steam mass flow rate and supersonic velocity to the Terry turbine bucket entrance, which are the necessary input information for the Terry turbine rotor model. The analytical models for the nozzle were validated with experimental data and benchmarked with CFD simulations. The analytical models generally agree well with the experimental data and CFD simulations. The analytical models are suitable for implementation into a reactor system analysis code or severe accident code as part of mechanistic and dynamical models to understand the RCIC behaviors. The newly developed nozzle models and modified turbine rotor model according to the Sandia’s original work have been implemented into RELAP-7, along with the original Sandia Terry turbine model. A new pump model has also been developed and implemented to couple with the Terry turbine model. An input

  15. Effects of gamma irradiation on medicinal plants and spices (2): Piper cubeba, piper nigrum, piper retrofractum, amomum cardamomum, and myristica fragrans

    Energy Technology Data Exchange (ETDEWEB)

    Chosdu, R.; Hilmy, N.; Bagiawati, S.; Sudiro, S. (National Atomic Energy Agency, Jakarta (Indonesia). Pasar Djumat Research Centre)

    1983-12-01

    Effects of gamma irradiation on essential oils of five medicinal plants i.e. dried seeds of piper cubeba(cubeb), piper nigrum(black pepper), piper retrofractum, amomum cardamomum(cardamom) and myristica fragrans(mace), packed in low density polyethylene bag of 0.13 mm thickness have been investigated. After being irradiated at doses of 5 and 10 kGy, a part of the samples was analysed, and the rest were stored for six months at temperature of 30 +- 2 degC, and humidity ranging from 70 to 95%. The essential oil characteristics of control, irradiated and six month stored samples were analysed using infrared and ultraviolet spectrophotometers, HPLC, GLC and refractometer. Other parameters observed were moisture content and essential oil content of the samples. Results showed that irradiation up to a dose of 10 kGy do not give any significant effect on these parameters. Significant changes were only found in the essential oil content of piper cubeba, caused by storage treatment.

  16. 76 FR 36395 - Airworthiness Directives; Piper Aircraft, Inc. Models PA-24, PA-24-250, and PA-24-260 Airplanes

    Science.gov (United States)

    2011-06-22

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... proposed AD, contact Piper Aircraft, Inc., 2926 Piper Drive, Vero Beach, Florida 32960; telephone: (772... September 15, 2004. This SAIB alerted owners and operators of Piper Aircraft, Inc. (Piper) Models PA-23,...

  17. Bioactivities of Piper aduncum L. and Piper obliquum Ruiz & Pavon (Piperaceae) essential oils from Eastern Ecuador.

    Science.gov (United States)

    Guerrini, Alessandra; Sacchetti, Gianni; Rossi, Damiano; Paganetto, Guglielmo; Muzzoli, Mariavittoria; Andreotti, Elisa; Tognolini, Massimiliano; Maldonado, Maria E; Bruni, Renato

    2009-01-01

    Essential oils from aerial parts of Piper aduncum (Matico) and Piper obliquum (Anis del Oriente) of ecuadorian origin were analyzed by GC-FID, GC-MS, (13)C NMR and their biological and pharmacological activities were assessed. Chemical composition proved to be unusually different from previous reports for safrole-rich P. obliquum (45.8%), while P. aduncum main constituent was dillapiol (45.9%). No genotoxic activity was found in the Ames/Salmonella typhimurium (TA98 and TA100) assay, either with or without S9 activation. Mutagen-protective properties, evaluated using sodium azide, 2-nitrofluorene and 2-aminoanthracene as mutagens/promutagens, was observed against promutagen 2-aminoanthracene, likely in consequence of microsomial deactivation. Antimicrobial assays have been performed on Gram+/Gram- bacteria, dermatophyte and phytopathogenic fungi and best results were provided by P. aduncum against fungal strains with complete inhibition at 500μg/ml. Preliminary analgesic and antithrombotic activities evidenced the absence of the former in hot plate and edema assays and a limited antiplatelet action against three different agonists (ADP, AA and U46619). Both oils have a very limited antioxidant capacity. Copyright © 2008 Elsevier B.V. All rights reserved.

  18. Amides from Piper as a Diuretic: Behind the Ethnopharmacological Uses of Piper glabratum Kunth

    Directory of Open Access Journals (Sweden)

    Thiago Bruno Lima Prando

    2014-01-01

    Full Text Available Several species of the genus Piper are known in Brazilian folk medicine as having diuretic activity. So, we propose to investigate the acute diuretic activity and the possible toxic effects of Piper glabratum Kunth, popularly known as false Jaborandi. Additionally, we propose to check whether there is any correlation between the biological activities of the crude extract (MEPG and its 2-methoxy-4,5-methylenedioxy-trans-cinnamoyl-pyrrolidine (MMCP in Wistar rats. The MEPG was fractioned by chromatography column and the MMCP was identified by analyses of 1H and 13C RMN spectral data and correlations. Both MEPG and MMCP were assayed for diuretic activity. The preparations obtained were orally administered in a single dose to rats. The urine excretion, pH, density, conductivity, and content of Na+, K+, Cl−, and HCO3- were measured in the urine of saline-loaded animals. Additionally, acute toxicity of the extract was also evaluated. MMCP at doses of 30 mg/kg was able to increase the urine volume, pH, and HCO3- excretion. Moreover, high dosage of MEPG showed important liver toxicity and elevated mortality when injected intraperitoneally. The results indicate that the MMCP shows important diuretic properties when administered in Wistar rats. Additionally, MEPG can induce important acute toxicity if given in high doses.

  19. Amides from Piper as a Diuretic: Behind the Ethnopharmacological Uses of Piper glabratum Kunth

    Science.gov (United States)

    Prando, Thiago Bruno Lima; Baciquete, Tatiane da Fonseca; Vieira, Jennifer Alexandra Castanho; Bressan, Jaqueline; Gasparotto, Francielly Mourão; Jesus, Douglas Rossi; Cardozo Junior, Euclides Lara; Lourenço, Emerson Luiz Botelho; Gasparotto Junior, Arquimedes

    2014-01-01

    Several species of the genus Piper are known in Brazilian folk medicine as having diuretic activity. So, we propose to investigate the acute diuretic activity and the possible toxic effects of Piper glabratum Kunth, popularly known as false Jaborandi. Additionally, we propose to check whether there is any correlation between the biological activities of the crude extract (MEPG) and its 2-methoxy-4,5-methylenedioxy-trans-cinnamoyl-pyrrolidine (MMCP) in Wistar rats. The MEPG was fractioned by chromatography column and the MMCP was identified by analyses of 1H and 13C RMN spectral data and correlations. Both MEPG and MMCP were assayed for diuretic activity. The preparations obtained were orally administered in a single dose to rats. The urine excretion, pH, density, conductivity, and content of Na+, K+, Cl−, and HCO3− were measured in the urine of saline-loaded animals. Additionally, acute toxicity of the extract was also evaluated. MMCP at doses of 30 mg/kg was able to increase the urine volume, pH, and HCO3− excretion. Moreover, high dosage of MEPG showed important liver toxicity and elevated mortality when injected intraperitoneally. The results indicate that the MMCP shows important diuretic properties when administered in Wistar rats. Additionally, MEPG can induce important acute toxicity if given in high doses. PMID:25101133

  20. Genetic diversity analysis in Piper species (Piperaceae) using RAPD markers.

    Science.gov (United States)

    Sen, Sandeep; Skaria, Reby; Abdul Muneer, P M

    2010-09-01

    The genetic diversity of eight species of Piper (Piperaceae) viz., P. nigrum, P. longum, P. betle, P. chaba, P. argyrophyllum, P. trichostachyon, P. galeatum, and P. hymenophyllum from Kerala state, India were analyzed by Random amplified polymorphic DNA (RAPD). Out of 22 10-mer RAPD primers screened, 11 were selected for comparative analysis of different species of Piper. High genetic variations were found among different Piper species studied. Among the total of 149 RAPD fragments amplified, 12 bands (8.05%) were found monomorphic in eight species. The remaining 137 fragments were found polymorphic (91.95%). Species-specific bands were found in all eight species studied. The average gene diversity or heterozygosity (H) was 0.33 across all the species, genetic distances ranged from 0.21 to 0.69. The results of this study will facilitate germplasm identification, management, and conservation.

  1. Antimalarial activity of methanolic leaf extract of Piper betle L.

    Science.gov (United States)

    Al-Adhroey, Abdulelah H; Nor, Zurainee M; Al-Mekhlafi, Hesham M; Amran, Adel A; Mahmud, Rohela

    2010-12-28

    The need for new compounds active against malaria parasites is made more urgent by the rapid spread of drug-resistance to available antimalarial drugs. The crude methanol extract of Piper betle leaves (50-400 mg/kg) was investigated for its antimalarial activity against Plasmodium berghei (NK65) during early and established infections. The phytochemical and antioxidant potentials of the crude extract were evaluated to elucidate the possibilities of its antimalarial effects. The safety of the extract was also investigated in ICR mice of both sexes by the acute oral toxicity limit test. The leaf extract demonstrated significant (P Piper betle leaves is toxicologically safe by oral administration. The results suggest that the Malaysian folklorical medicinal application of the extract of Piper betle leaf has a pharmacological basis.

  2. Concept of the CMS Trigger Supervisor

    CERN Document Server

    Magrans de Abril, Ildefons; Varela, Joao

    2006-01-01

    The Trigger Supervisor is an online software system designed for the CMS experiment at CERN. Its purpose is to provide a framework to set up, test, operate and monitor the trigger components on one hand and to manage their interplay and the information exchange with the run control part of the data acquisition system on the other. The Trigger Supervisor is conceived to provide a simple and homogeneous client interface to the online software infrastructure of the trigger subsystems. This document specifies the functional and non-functional requirements, design and operational details, and the components that will be delivered in order to facilitate a smooth integration of the trigger software in the context of CMS.

  3. Alkaloids from piper: a review of its phytochemistry and pharmacology.

    Science.gov (United States)

    Gutierrez, Rosa Martha Perez; Gonzalez, Adriana Maria Neira; Hoyo-Vadillo, Carlos

    2013-02-01

    Piper has been used for long timelike condiment and food, but also in traditional medicine around of the world. This work resumes the available and up to date work done on members of the Piperaceae family and their uses for therapeutic purposes. Information on Piper genus was gathered via internet using scientific databases such as Scirus, Google Scholar, CAB-abstracts, MedlinePlus, Pubmed, SciFinder, Scopus and Web of Science. The largeleafed perennial plant Piper is used for its spicy aromatic scent and flavor. It has an important presence in the cuisine of different cultures. Another quality of these plants is their known medicinal properties. It has been used as emollient, antirheumatic, diuretic, stimulant, abortifacient, anti-inflammatory, antibacterial, antifungal and antidermatophytic. A survey of the literature shows that the genus Piper is mainly known for its alkaloids with cytotoxic, chemopreventive, antimetastatic and antitumor properties in several types of cancer. Studies of its alkaloids highlight the existence of various potential leads to develop new anti-cancer agents. Modern pharmacology studies have demonstrated that its crude extracts and active compounds possess wide pharmacological activities, especially asantioxidant, anti-depressive, hepatoprotective, antimicrobial, anti-obesity, neuropharmacological, to treat cognitive disorders, anti-hyperlipidemic, anti-feedant, cardioactive, immuno-enhancing, and anti-inflamatory. All this evidence supporting its traditional uses. This review summarizes the up-to-date and comprehensive information concerning the botany, traditional use, phytochemistry and pharmacology of Piper together with its toxicology, and discusses the possible trend and scope for further research on Piper in the future.

  4. The importance of provision and utilization of supervisor support.

    Science.gov (United States)

    Munc, Alec; Eschleman, Kevin; Donnelly, Janet

    2016-10-10

    Three cross-sectional studies examined the benefits of provision of supervisor support while controlling for subordinate utilization of supervisor support. Data were collected from workers in a subordinate role (Study 1 N = 355; Study 2 N = 229; Study 3 N = 109). Consistent with expectations, provision of supervisor support consistently explained unique variance in affective job criteria while controlling for utilization of supervisor support. The results indicate that supervisors should acknowledge that their workers experience the affective benefits of supervisor support even if the workers do not consistently use the support provided. Contrary to expectations, provision of supervisor support did not consistently explain unique variance in perceived job stressors while controlling for utilization of supervisor support. However, workers must utilize the supervisor support provided in order to perceive fewer job stressors. We recommend supervisors to take caution when relocating their support to different subordinates based solely on a lack of utilization of support, as this may cause higher perceived job stressors for their subordinates based on the lack of provision of that support.

  5. In vitro conservation of Piper aduncum and Piper hispidinervum under slow-growth conditions

    Directory of Open Access Journals (Sweden)

    Tatiane Loureiro da Silva

    2011-04-01

    Full Text Available The objective of this work was to evaluate in vitro storage of Piper aduncum and P. hispidinervum under slow-growth conditions. Shoots were stored at low temperatures (10, 20 and 25°C, and the culture medium was supplemented with osmotic agents (sucrose and mannitol - at 1, 2 and 3% and abiscisic acid - ABA (0, 0.5, 1.0, 2.0 and 3.0 mg L-1. After six-months of storage, shoots were evaluated for survival and regrowth. Low temperature at 20ºC was effective for the in vitro conservation of P. aduncum and P. hispidinervum shoots. In vitro cultures maintained at 20ºC on MS medium showed 100% survival with slow-growth shoots. The presence of mannitol or ABA, in the culture medium, negatively affected shoot growth, which is evidenced by the low rate of recovered shoots.

  6. Child Sacrifice: Black America's Price of Paying the Media Piper.

    Science.gov (United States)

    Orange, Carolyn M.; George, Amiso M.

    2000-01-01

    Explores the sacrifice of African American children to the broadcast media and video games in terms of the players ("media pipers"), the messages ("piping"), and the consequences to children. Proposes some solutions for the problems associated with excessive television viewing and undesirable programming. (SLD)

  7. Two new sphingolipids from the leaves of Piper betle L.

    Science.gov (United States)

    Chen, Duo-Zhi; Xiong, Hua-Bin; Tian, Kai; Guo, Jun-Ming; Huang, Xiang-Zhong; Jiang, Zhi-Yong

    2013-09-12

    Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay.

  8. Two New Sphingolipids from the Leaves of Piper betle L.

    OpenAIRE

    Zhi-Yong Jiang; Xiang-Zhong Huang; Jun-Ming Guo; Kai Tian; Hua-Bin Xiong; Duo-Zhi Chen

    2013-01-01

    Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay.

  9. Piper (Piperaceae) in the Solomon Islands: the climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2010-01-01

    Eleven climbing species of Piper in the Solomon Islands are recognized: P. abbreviatum, P. betle, P. bosnicanum, P. caninum, P. celtidiforme, P. fragile, P. insectifugum (syn. P. austrocaledonicum), P. interruptum, P. macropiper, P. majusculum, and, as the only endemic, P. sclerophloeum, for which a

  10. Two New Sphingolipids from the Leaves of Piper betle L.

    Directory of Open Access Journals (Sweden)

    Zhi-Yong Jiang

    2013-09-01

    Full Text Available Two new sphingolipids, pipercerebrosides A (1 and B (2, were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay.

  11. Dioxoaporphine alkaloid and flavones from piper manausense yunk.

    Directory of Open Access Journals (Sweden)

    A. M. P. de Díaz

    2010-07-01

    Full Text Available 1,2-Metilendioxi-6-metil-4H-dibenzo [de,g] quinolina -4,5(6H-diona; 5-hidroxi-4',7-dimetoxiflavona; ^sitosterol; estigmasterol y esteres de los ácidos láurlco y esteárico, fueron aislados del tallo de Piper manausense Yunk (Piperaceae

  12. Piper (Piperaceae) in the Solomon Islands: the climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2010-01-01

    Eleven climbing species of Piper in the Solomon Islands are recognized: P. abbreviatum, P. betle, P. bosnicanum, P. caninum, P. celtidiforme, P. fragile, P. insectifugum (syn. P. austrocaledonicum), P. interruptum, P. macropiper, P. majusculum, and, as the only endemic, P. sclerophloeum, for which a

  13. Piper (Piperaceae) in New Guinea: the non-climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2003-01-01

    A taxonomic account is given of six Piper species of New Guinea: P. bolanicum spec. nov., P. gibbil­imbum, P. recessum spec. nov., P. subbullatum, P. triangulare and P. wabagense. These small shrubby trees are best represented in secondary growth and forest at 1300–2500 m altitude, with P.

  14. Lignan profile of Piper cubeba, an Indonesian medicinal plant

    NARCIS (Netherlands)

    Elfahmi, [No Value; Ruslan, Komar; Batterman, Sieb; Bos, Rein; Kayser, Oliver; Woerdenbag, Herman J.; Quax, Wim J.

    The lignan profile of the aerial part of Piper cubeba L. (Piperaceae) was determined using GC, GC-MS and HPLC. The number of lignans found in the leaves was 15, followed by berries and the stalks with respectively 13 and five lignans. This is the first investigation of lignans from the leaves and

  15. Piper (Piperaceae) in New Guinea: the climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2012-01-01

    Sixteen climbing Piper species are accepted for New Guinea. The three endemics, P. arfakianum, P. subcanirameum and P. versteegii, are fully described. Eight taxa of unclear circumscription are noted. A new variety of P. macropiper, endemic to Morobe Province of Papua New Guinea, is described. The

  16. A new species of Piper (Piperaceae) from the Seychelles

    NARCIS (Netherlands)

    Gerlach, Justin

    2002-01-01

    A new species of Piper (Piperaceae), P. silhouettanum, is described from the Anse Mondon river valley, Silhouette Island, Seychelles. This species is close to P. nigrum but distinguished by its different venation, glabrous leaves, persistent elongated stipules and reduced bracts. This species is

  17. Child Sacrifice: Black America's Price of Paying the Media Piper.

    Science.gov (United States)

    Orange, Carolyn M.; George, Amiso M.

    2000-01-01

    Explores the sacrifice of African American children to the broadcast media and video games in terms of the players ("media pipers"), the messages ("piping"), and the consequences to children. Proposes some solutions for the problems associated with excessive television viewing and undesirable programming. (SLD)

  18. Piper (Piperaceae) in New Guinea: the climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2012-01-01

    Sixteen climbing Piper species are accepted for New Guinea. The three endemics, P. arfakianum, P. subcanirameum and P. versteegii, are fully described. Eight taxa of unclear circumscription are noted. A new variety of P. macropiper, endemic to Morobe Province of Papua New Guinea, is described. The p

  19. A new species of Piper (Piperaceae) from the Seychelles

    NARCIS (Netherlands)

    Gerlach, Justin

    2002-01-01

    A new species of Piper (Piperaceae), P. silhouettanum, is described from the Anse Mondon river valley, Silhouette Island, Seychelles. This species is close to P. nigrum but distinguished by its different venation, glabrous leaves, persistent elongated stipules and reduced bracts. This species is res

  20. Piper (Piperaceae) in New Guinea: the non-climbing species

    NARCIS (Netherlands)

    Gardner, R.O.

    2003-01-01

    A taxonomic account is given of six Piper species of New Guinea: P. bolanicum spec. nov., P. gibbil­imbum, P. recessum spec. nov., P. subbullatum, P. triangulare and P. wabagense. These small shrubby trees are best represented in secondary growth and forest at 1300–2500 m altitude, with P. gibbilimb

  1. A SPECTROPHOTOMETRIC METHOD TO ESTIMATE PIPERINE IN PIPER SPECIES

    OpenAIRE

    1998-01-01

    A Simple, rapid and economical procedure for estimation of piperine by UV Spectrophotometer in different piper species was developed and is described. The method is based on method is based on the identification of piperine by TLC and on the ultra violet absorbance maxima in alcohol at 328 nm.

  2. Antifungal activity of Piper diospyrifolium Kunth (Piperaceae) essential oil

    Science.gov (United States)

    Vieira, Silvia Cristina Heredia; de Paulo, Luis Fernando; Svidzinski, Terezinha Inez Estivaleti; Dias Filho, Benedito Prado; Nakamura, Celso Vataru; de Souza, Amanda; Young, Maria Cláudia Marx; Cortez, Diógenes Aparício Garcia

    2011-01-01

    In vitro activity of the essential oil from Piper diospyrifolium leaves was tested using disk diffusion techniques. The antifungal assay showed significant potencial antifungal activity: the oil was effective against several clinical fungal strains. The majority compounds in the essential oil were identified as sesquiterpenoids by GC-MS and GC-FID techniques. PMID:24031717

  3. Pygmalion effects among outreach supervisors and tutors: extending sex generalizability.

    Science.gov (United States)

    Natanovich, Gloria; Eden, Dov

    2008-11-01

    Students who supervised other students who tutored grade-school pupils in a university-based outreach program were randomly assigned to Pygmalion and control conditions. Experimental supervisors were told that their tutors were ideally qualified for their tutoring role; control supervisors were told nothing about their tutors' qualifications. A manipulation check revealed that the experimental supervisors expected more of their tutors. Analysis of variance of tutorial success measures confirmed the Pygmalion effect among supervisors of both sexes. No main effect or interaction involving either supervisor sex or tutor sex was significant. As predicted, the experimental supervisors also provided better leadership and the experimental tutors increased their self-efficacy. This was the first demonstration of the Pygmalion effect among women leading men. Pygmalion effects may be produced without regard for sex.

  4. Correspondence of supervisor and subordinate perspectives during major organizational change.

    Science.gov (United States)

    Leiter, M P; Harvie, P

    1997-10-01

    Staff members (N = 2,605) and supervisors (N = 55) of 39 administrative units in 2 healthcare organizations completed a survey measuring confidence in the organization, engagement with their work, and occupational hazards. A correlational analysis determined correspondence between the perspectives of supervisors with those of staff reporting to them as their facilities adjusted to major organizational changes. Supervisors' scores were significantly and positively correlated with the corresponding scores of staff members on cynicism, meaningfulness, acceptance of change, goals, hospital reputation, and health risks. Regression analysis found that relationships were relatively domain specific: Supervisor engagement with work was positively related to that of their staff members, and supervisors evaluations of the organization were positively related to those of their staff members. Supervisor assessment of occupational hazards was related to all 3 areas of staff perception.

  5. End-of-Life Issues in the United States after Terri Schiavo: Implications for Social Work Practice

    Directory of Open Access Journals (Sweden)

    Darrel Montero

    2011-09-01

    Full Text Available The very public death of Terri Schiavo in 2005 alerted Americans to what is a growing ethical, medical, and social crisis: the status of end-of-life issues and decisions in the United States. Currently, Oregon is the only state to give terminally ill patients the right to end their lives, with physicians’ help, if they so choose. Public opinion data from 1977 to the present show that Americans support greater rights for individuals facing end-of-life decisions--up to and including physician-assisted suicide and euthanasia. This paper considers the status of end-of-life issues in the United States after Terri Schiavo’s death and examines the opportunities for advocacy by social workers who serve clients and families encountering this complex and controversial issue.

  6. Doctoral Supervisor Education in Denmark: Aiming to foster reflective practitioners

    DEFF Research Database (Denmark)

    Godskesen, Mirjam Irene; Wichmann-Hansen, Gitte; Kobayashi, Sofie

    Quality in doctoral supervision is an increasing organisational focus area for universities and the need for supervisor development and training is widely recognised. However, there is no systematic overview of competence development activities for doctoral supervisors in Europe in general and th......, the content and the quality criteria for good supervisor education. We hope that these insights can inspire the development in other European countries....

  7. Internship in School Psychology: Education and practice of the supervisor

    OpenAIRE

    Silva Neto, Walter Mariano de Faria; Guzzo,Raquel Souza Lobo

    2016-01-01

    The aim of the study was to investigate the training and practice of the internship supervisor in the field of Educational Psychology. The research was carried out through semi-structured interviews with six internship supervisors. Data was collected into three groups, as follows: characteristics of the supervisor (emphasis on the importance of his/her personal and professional background); relationship with the working setting (knowledge on curriculum structure and on the relationship betwee...

  8. On the contemporary – and contemporary art history. A review of Terry Smith, What Is Contemporary Art

    OpenAIRE

    Anthony Gardner; Huw Hallam

    2011-01-01

    This analysis of Terry Smith’s 'What Is Contemporary Art?' evaluates Smith’s ongoing project to theorise contemporary art around the theme of multiple, interconnected temporalities. It questions how this ‘contemporaneity’ differs from the classic teleologism of modernism and postmodern relativism and suggests that Smith’s categories may be valuable for understanding other cultural areas, such as contemporary music. It then raises methodological problems associated with charting the terrain of...

  9. Comparative Physicochemical Evaluation of Fruits and Anti depressant Potential of volatile oils of fruits of Local Piper Species

    Directory of Open Access Journals (Sweden)

    Mohib Khan

    2015-03-01

    Full Text Available In this study an attempt is made to evaluate physicochemical properties comparatively for the fruits of different Piper species available in the Mumbai region. The fruits of five species, viz. Piper betle Linn, Piper cubeba Linn. f., Piper retrofractum Vahl, Piper longum Linn and Piper nigrum Linn were evaluated comparatively for physicochemical properties, viz. Ash Value, Extractive Value, Loss on Drying, Mucilage Content, Crude Fibre Content, Volatile Oil Content and Piperine Content by Spectroscopic method. At the same time an attempt is made to evaluate antidepressant potential comparatively for the volatile oils of mentioned species, using forced swimming method, on albino mice with fluoxetine as standard antidepressant drug.

  10. 29 CFR 1960.55 - Training of supervisors.

    Science.gov (United States)

    2010-07-01

    ... well as other appropriate rules and regulations. (b) This supervisory training should include introductory and specialized courses and materials which will enable supervisors to recognize and eliminate,...

  11. A Comparison of Female Supervisors in Business and Government Organizations

    Science.gov (United States)

    DiMarco, Nicholas; Whitsitt, Susan E.

    1975-01-01

    This exploratory study compared the life style and interpersonal need orientation, leadership style, and perception of the organization structure of female supervisors in business and government organizations. (Author)

  12. An investigation of the vegetative anatomy of Piper sarmentosum, and a comparison with the anatomy of Piper betle (Piperaceae)

    Science.gov (United States)

    Piper sarmentosum Roxb. (synonym, P. lolot C.DC.) is a southeast Asian medicinal plant valued for its medicinal and culinary uses. Hand-sections of the vegetative parts of P. sarmentosum were prepared and the anatomical features were studied by light microscopy and scanning electron microscopy. Th...

  13. Anticancer Principles from Medicinal Piper (胡椒 Hú Jiāo Plants

    Directory of Open Access Journals (Sweden)

    Yue-Hu Wang

    2014-01-01

    Full Text Available The ethnomedical uses of Piper (胡椒 Hú Jiāo plants as anticancer agents, in vitro cytotoxic activity of both extracts and compounds from Piper plants, and in vivo antitumor activity and mechanism of action of selected compounds are reviewed in the present paper. The genus Piper (Piperaceae contains approximately 2000 species, of which 10 species have been used in traditional medicines to treat cancer or cancer-like symptoms. Studies have shown that 35 extracts from 24 Piper species and 32 compounds from Piper plants possess cytotoxic activity. Amide alkaloids account for 53% of the major active principles. Among them, piplartine (piperlongumine shows the most promise, being toxic to dozens of cancer cell lines and having excellent in vivo activity. It is worthwhile to conduct further anticancer studies both in vitro and in vivo on Piper plants and their active principles.

  14. Supervisor trainees' and their supervisors' perceptions of attainment of knowledge and skills: an empirical evaluation of a psychotherapy supervisor training programme.

    Science.gov (United States)

    Sundin, Eva C; Ogren, Marie-Louise; Boëthius, Siv Boalt

    2008-11-01

    This study aimed to evaluate the success of a 2-year, part-time training programme for psychotherapy supervisors. A second aim was to examine factors that might contribute to perceived knowledge and skills attainment during the training course. This is a naturalistic, longitudinal study where several measures are used to examine group process and outcome. Supervisor trainees' (N=21) and their facilitators' (N=6) ratings of learning (knowledge and skills), relations to the supervisor and supervision group, usage of the group, and supervisor style were completed at three time points. The findings suggested that both trainees and their supervisors perceived that the trainees attained a substantial amount of knowledge and skills during the course. In accordance with the literature and expectations, the regression analysis suggested a strong negative association between a strong focus on group processes in the initial and middle phases of the training and perceived knowledge and skills attainment in the final phase of the training. The expected, positive role of relations among trainees in the supervision group in the first half of the training and perceived knowledge and skills attainment in the final part of the training was obtained, whilst the hypothesized significance of the relationship between trainee and supervisor did not receive support. The supervisory course seemed to provide a training that allowed trainees to attain knowledge and skills that are necessary for psychotherapy supervisors. The results of this pilot study also emphasize the need of more research on learning in the context of group supervision in psychotherapy.

  15. Chemical Composition and Biological Activity of Essential Oils from Different Species of Piper from Panama.

    Science.gov (United States)

    Santana, Ana I; Vila, Roser; Cañigueral, Salvador; Gupta, Mahabir P

    2016-07-01

    The chemical composition of leaf essential oils from 11 species of Piper from Panama was analyzed by a combination GC-FID and GC-MS procedures. Six of them had sesquiterpene hydrocarbons as major constituents, three were characterized by monoterpene hydrocarbons, one by a diterpene, and one by a phenylpropanoid, dillapiole. The main components identified in each species were: cembratrienol (25.4 %) in Piper augustum; β-pinene (26.6 %) in Piper corrugatum; α-pinene (19.4 %) in Piper curtispicum; trans-β-farnesene (63.7 %) in Piper darienense; p-cymene (43.9 %) in Piper grande; dillapiole (57.7 %) in Piper hispidum; linalool (14.5 %), α-phellandrene (13.8 %), and limonene (12.2 %) in Piper jacquemontianum; β-caryophyllene (45.2 %) in Piper longispicum; linalool (16.5 %), α-phellandrene (11.8 %), limonene (11.4 %), and p-cymene (9.0 %) in Piper multiplinervium; β-selinene (19.0 %), β-elemene (16.1 %), and α-selinene (15.5 %) in Piper reticulatum; and germacrene D (19.7 %) in Piper trigonum. The essential oils of P. hispidum and P. longispicum at a concentration of 250 µg/mL showed larvicidal activity against Aedes aegypti, while the oils from P. curtispicum, P. multiplinervium, P. reticulatum, and P. trigonum were inactive (LC100 ≥ 500 µg/mL). The essential oils of P. grande, P. jacquemontianum, and P. multiplinervium showed no significant antifungal activity (MIC > 250 µg/mL) against several yeasts and filamentous fungal strains. Georg Thieme Verlag KG Stuttgart · New York.

  16. PHARMACOGNOSTIC, PHYTOCHEMICAL AND PHYSICOCHEMICAL STUDIES OF PIPER NIGRUM LINN. FRUIT (PIPERACEAE)

    OpenAIRE

    Kadam, P. V.; K.N. Yadav; F.A. Patel; F.A. Karjikar; M J Patil

    2013-01-01

    Piper species are reported to have great medicinal value in Indian medicine. Fruits of Piper nigrum Linn is commonly known as “Kalimiri” belongs to the family of Piperaceae and widely used as a pungent condiment. Traditionally it is used as antipyretic, diuretic, aphrodisiac, immune-stimulant, antioxidant, hepatoprotective, digestive, rubefacient, counter irritant, antiseptic, antispasmodic agent. Present work is related to standardization of Piper nigrum by using Pharmacognostic (Macroscopy,...

  17. The underlying mechanism of action for various medicinal properties of Piper betle (betel).

    Science.gov (United States)

    Haslan, H; Suhaimi, F H; Thent, Zar Chi; Das, S

    2015-01-01

    Piper betle (betel) plant belongs to the Piperaceae family. Piper. betle is widely known for its potent medicinal properties. Various active compounds are present in Piper. betle such as allylpyrocatechol, hydroxychavicol, piperbetol, ethylpiperbetol, piperol A, piperol B, chavibetol, and alkaloids which account for these beneficial medicinal properties. In the present narrative review, we looked into the various active compounds present in the Piper betle and attempted to understand their underlying mechanism of action. Proper understanding of the molecular biology involving the mechanism of action may help in better drug formulation and provide better therapeutic actions in the field of alternative and complementary medicine.

  18. PHARMACOGNOSTIC, PHYTOCHEMICAL AND PHYSICOCHEMICAL STUDIES OF PIPER NIGRUM LINN. FRUIT (PIPERACEAE

    Directory of Open Access Journals (Sweden)

    P.V. Kadam

    2013-06-01

    Full Text Available Piper species are reported to have great medicinal value in Indian medicine. Fruits of Piper nigrum Linn is commonly known as “Kalimiri” belongs to the family of Piperaceae and widely used as a pungent condiment. Traditionally it is used as antipyretic, diuretic, aphrodisiac, immune-stimulant, antioxidant, hepatoprotective, digestive, rubefacient, counter irritant, antiseptic, antispasmodic agent. Present work is related to standardization of Piper nigrum by using Pharmacognostic (Macroscopy, Cytomorphology, Physical constants and Photochemical study of fruit. All parameters were studied according to the WHO and Pharmacopoeial guidelines to standardize the Piper nigrum.

  19. SIX IDEAS IN SEARCH OF SUPERVISORS OF ENGLISH.

    Science.gov (United States)

    ROBERTSON, ROBERT T.

    AS ENGLISH SUPERVISORS SEEK TO IMPROVE THE TEACHING OF ENGLISH, THEY SHOULD CONSIDER THAT DEVELOPMENTS IN OTHER SCHOOLS DO NOT ALWAYS SUIT LOCAL CONDITIONS AND THAT PRESENT CHANGE IN THE TEACHING OF ENGLISH ALLOWS TEACHERS TO EXPERIMENT FREELY IN THEIR CLASSROOMS. IN LIGHT OF THIS FREEDOM TO INNOVATE, SUPERVISORS MAY FIND THE FOLLOWING SIX IDEAS…

  20. Care, Thoughtfulness, and Tact: A Conceptual Framework for University Supervisors

    Science.gov (United States)

    Cuenca, Alexander

    2010-01-01

    The pedagogical work of university supervisors has received little attention in teacher education literature. Based on this concern, this paper provides a conceptual framework for university supervisors, recasting their role as teacher pedagogues focused on responding to the particular contextual needs of student teachers as they learn to teach.…

  1. Development and Initial Psychometrics of Counseling Supervisor's Behavior Questionnaire

    Science.gov (United States)

    Lee, Ahram; Park, Eun Hye; Byeon, Eunji; Lee, Sang Min

    2016-01-01

    This study describes the development and psychometric properties of the Counseling Supervisor's Behavior Questionnaire, designed to assess the specific behaviors of supervisors, which can be observed by supervisees during supervision sessions. Factor structure, construct and concurrent validity, and internal consistency reliability of the…

  2. How Federal Employees and Supervisors View Performance Standards.

    Science.gov (United States)

    Rampp, Lary C.; And Others

    A semantic differential instrument of four scales was used to evaluate employees' and supervisors' attitudes toward a differentiated performance appraisal training process. The sample included 237 employees and 83 supervisors in the Health Resources Administration of the U.S. Department of Health and Human Services. The study found the instrument…

  3. Supervisor Use of Video as a Tool in Teacher Reflection

    Science.gov (United States)

    Baecher, Laura; McCormack, Bede; Kung, Shiao-Chuan

    2014-01-01

    Supervisors play a critical role in fostering teacher candidates' reflective thinking on their practice, yet too often it is the supervisor, rather than the teacher, doing most of the observation work. Video-based supervision offers a promising alternative, as teachers have an opportunity to examine their own lesson and thus engage with the…

  4. The Role of Supervisors' and Supervisees' Mindfulness in Clinical Supervision

    Science.gov (United States)

    Daniel, Laura; Borders, L. DiAnne; Willse, John

    2015-01-01

    The authors explored whether supervisor and supervisee self-ratings of mindfulness (N = 72 supervision pairs) predicted perceptions of the supervisory relationship and session dynamics. Only supervisor self-ratings of mindfulness predicted their own ratings of the supervisory relationship and session dynamics.

  5. 42 CFR 493.1461 - Standard: General supervisor qualifications.

    Science.gov (United States)

    2010-10-01

    ..., oral pathology, dermatopathology, and ophthalmic pathology because all tests and examinations, must be... supervisor under §§ 493.1449(b) or 493.1449(l) or (2); (3) In ophthalmic pathology, by an individual who is qualified as a technical supervisor under §§ 493.1449(b) or 493.1449(1)(3); and (4) In oral pathology, by...

  6. Training the Trainers: Learning to Be a Principal Supervisor

    Science.gov (United States)

    Saltzman, Amy

    2017-01-01

    While most principal supervisors are former principals themselves, few come to the role with specific training in how to do the job effectively. For this reason, both the Washington, D.C., and Tulsa, Oklahoma, principal supervisor programs include a strong professional development component. In this article, the author takes a look inside these…

  7. A Good Supervisor--Ten Facts of Caring Supervision

    Science.gov (United States)

    Määttä, Kaarina

    2015-01-01

    This article describes the elements of caring supervision of doctoral theses. The purpose was to describe the best practices as well as challenges of supervision especially from the supervisor's perspective. The analysis is based on the author's extensive experience as a supervisor and related data obtained for research and developmental purposes.…

  8. Impressed by impression management: Newcomer reactions to ingratiated supervisors.

    Science.gov (United States)

    Foulk, Trevor A; Long, David M

    2016-10-01

    Organizational newcomers are unfamiliar with many aspects of their workplace and look for information to help them reduce uncertainty and better understand their new environment. One aspect critical to newcomers is the disposition of their supervisor-the person who arguably can impact the newcomer's career the most. To form an impression of their new supervisor, newcomers look to social cues from coworkers who have interpersonal contact with the supervisor. In the present research, we investigate the ways newcomers use observed ingratiation-a common impression management strategy whereby coworkers try to appear likable (Schlenker, 1980)-to form impressions of a supervisor's warmth. Research on social influence cannot easily account for how third parties will interpret ingratiation, as the behaviors linked to ingratiation suggest something positive about the target, yet the unsavory aspects of the behavior imply it may not have the same effects as other positive behaviors. Our findings suggest that newcomers are unique in that they are motivated to learn about their new supervisor, and are prone to ignore those unsavory aspects and infer something positive about a supervisor targeted with ingratiation. Our findings also suggest that this effect can be weakened based on the supervisor's response. In other words, newcomers rely less on evidence from a coworker's ingratiation in the presence of direct behaviors from the supervisor. (PsycINFO Database Record

  9. "In Loco Paedagogus:" The Pedagogy of a Novice University Supervisor

    Science.gov (United States)

    Cuenca, Alexander

    2010-01-01

    The peripherality of the university supervisor during the student teaching experience has often been considered extraneous to the work of preparing preservice teachers. Despite the supervisor's potential to support learning, the low status of supervision in the preparation of prospective teachers has led to a lack of commitment in preparing,…

  10. The Experiences of Expert Group Work Supervisors: An Exploratory Study

    Science.gov (United States)

    Atieno Okech, Jane E.; Rubel, Deborah

    2009-01-01

    Evaluation of group work supervision literature suggests that description of expert group work supervisors' experiences could be useful for expanding existing group work supervision practices and models. This study provided a systematic exploration of the experiences of expert group work supervisors during the supervision process. Results indicate…

  11. Counselors' and Supervisors' Perceptions of Professional Development Practices.

    Science.gov (United States)

    Richardson, Bill K.; Obermann, C. Esco

    This paper examines the perceptions of state agency vocational rehabilitation counselors and supervisors in regard to the values they attach to present inservice education programs and to supervision. Subjects were 282 rehabilitation counselors and 64 supervisors employed in state and federal vocational rehabilitation programs in Iowa, Illinois,…

  12. Requirements for nurse supervisor training: A qualitative content analysis.

    Science.gov (United States)

    Dehghani, Khadijeh; Nasiriani, Khadijeh; Salimi, Tahere

    2016-01-01

    Supervisors should have certain characteristics and adequate preparation for their roles. Yet, there are no well-educated experts knowing about the supervisor's role and responsibilities and how to train them. So, this research was conducted with the purpose of finding the factors affecting nursing supervisor training. This research is an inductive content analysis. Participants were 25 in number, consisting of nurses and supervisors in Shahid Sadoughi University hospitals. The participants were chosen by a purposive sampling method. Data collection was done by semi-structured interviews and reviewing documents. Data were analyzed using conventional content analysis. Findings included two main themes: Firstly, establishment of a supervisory infrastructure that includes "making the appointments and retention of supervisors, clarifying the duties and authority of supervisor, developing supervisory culture, specializing supervision, and conducting practice-based training" and secondly, comprehensive supervisory competencies that include "acquiring scientific, managing, communicative, professional, ethical, pedagogical, and supporting adequacy." Clinical supervisor has a major role in ensuring the quality of nursing care. This leads to improvements in patient care and nurses' personal and professional development. So, it is necessary that for effective supervision in nursing, first an infrastructure is provided for supervision and then the comprehensive competency of a supervisor is enhanced to apply effective supervision.

  13. The Role of the Supervisor in the Supervisory Process

    Science.gov (United States)

    Lessing, A. C.

    2011-01-01

    Postgraduate supervision does not only require academic and research skills from the supervisors--they may also assume a variety of roles to support the postgraduate student from novice to experienced researcher. The role of supervisors in the supervisory process, as well as the views of a purposeful selection of lecturers on the role is the focus…

  14. Supervisor's Interactive Model of Organizational Relationships

    Science.gov (United States)

    O'Reilly, Frances L.; Matt, John; McCaw, William P.

    2014-01-01

    The Supervisor's Interactive Model of Organizational Relationships (SIMOR) integrates two models addressed in the leadership literature and then highlights the importance of relationships. The Supervisor's Interactive Model of Organizational Relationships combines the modified Hersey and Blanchard model of situational leadership, the…

  15. School Counseling Site Supervisor Training: A Web-Based Approach

    Science.gov (United States)

    Swank, Jacqueline M.; Tyson, Lawrence

    2012-01-01

    A need exists for training school counseling site supervisors in providing clinical supervision to school counseling practicum and internship students. This article outlines a Web-based training program containing six modules to assist counselor education programs in educating school counseling site supervisors. The authors also address the…

  16. Suicidal Clients and Supervisees: A Model for Considering Supervisor Roles

    Science.gov (United States)

    McGlothlin, Jason M.; Rainey, Steve; Kindsvatter, Aaron

    2005-01-01

    It is likely that counselor trainees will be exposed to suicidal clients and subsequently face personal dilemmas, stress, and feelings of incompetence. Ethical guidelines mandate that supervisors have procedures to assist supervisors in such times. Currently, the literature does not provide a framework for providing such supervision. This article…

  17. Applying Squeezing Technique to Clayrocks: Lessons Learned from Experiments at Mont Terri Rock Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, A. M.; Sanchez-Ledesma, D. M.; Tournassat, C.; Melon, A.; Gaucher, E.; Astudillo, E.; Vinsot, A.

    2013-07-01

    Knowledge of the pore water chemistry in clay rock formations plays an important role in determining radionuclide migration in the context of nuclear waste disposal. Among the different in situ and ex-situ techniques for pore water sampling in clay sediments and soils, squeezing technique dates back 115 years. Although different studies have been performed about the reliability and representativeness of squeezed pore waters, more of them were achieved on high porosity, high water content and unconsolidated clay sediments. A very few of them tackled the analysis of squeezed pore water from low-porosity, low water content and highly consolidated clay rocks. In this work, a specially designed and fabricated one-dimensional compression cell two directional fluid flow was used to extract and analyse the pore water composition of Opalinus Clay core samples from Mont Terri (Switzerland). The reproducibility of the technique is good and no ionic ultrafiltration, chemical fractionation or anion exclusion was found in the range of pressures analysed: 70-200 MPa. Pore waters extracted in this range of pressures do not decrease in concentration, which would indicate a dilution of water by mixing of the free pore water and the outer layers of double layer water (Donnan water). A threshold (safety) squeezing pressure of 175 MPa was established for avoiding membrane effects (ion filtering, anion exclusion, etc.) from clay particles induced by increasing pressures. Besides, the pore waters extracted at these pressures are representative of the Opalinus Clay formation from a direct comparison against in situ collected borehole waters. (Author)

  18. Coming soon - Launch of e-learning initiative for supervisors

    CERN Document Server

    2015-01-01

    In early July, the Learning and Development group is launching a new learning initiative specifically targeted at supervisors here at CERN. With the assistance of  experts on the subject, we have designed an exclusive series of five e-learning modules. These modules will help supervisors to synthesise some of the important processes that influence and impact their daily work and build key competencies as people managers.   Each module may take up to a maximum of 60 minutes to complete and covers the following topics: • CERN as an Organisation • People Management (Part 1) • People Management (Part 2) • Financial Management • Administrative Information Tools for Supervisors Supervisors will receive an invitation from the L&D group to access the modules on a dedicated e-learning space created on SharePoint. We recommend that all newly appointed supervisors access and complete the five modules within the first month of taking up their su...

  19. Role of commitment to the supervisor, leader-member exchange, and supervisor-based self-esteem in employee-supervisor conflicts.

    Science.gov (United States)

    Landry, Guylaine; Vandenberghe, Christian

    2009-02-01

    Using survey data from 240 employees working in a variety of organizations, the authors examined the relations among commitment to the supervisor, leader-member exchange, supervisor-based self-esteem (SBSE), and relationship and substantive supervisor-subordinate conflicts. They found affective commitment was negatively related to both types of conflicts; perceived lack of alternatives commitment was positively related to relationship conflicts; and leader-member exchange was negatively related to substantive conflicts. SBSE was negatively associated with both types of conflicts. In addition, when SBSE was low, affective commitment was more strongly related to both types of conflicts, and normative commitment more strongly and positively related to substantive conflicts. The authors discuss the implications of these findings for the understanding of employee-supervisor conflicts.

  20. Effects of Supervisor and Supervisee Theoretical Orientation and Supervisor-Supervisee Matching on Interns' Perceptions of Supervision.

    Science.gov (United States)

    Putney, Martha W.; And Others

    1992-01-01

    Findings from 84 interns from 32 nationwide training sites revealed that cognitive-behavioral supervisors were perceived to be in consultant role and to focus on skills and strategies more than were humanistic, psychodynamic, and existential supervisors, who were perceived more as using relationship model, playing therapist role, and focusing on…

  1. Origin of the subepidermal tissue in Piper L. leaves.

    Science.gov (United States)

    Nakamura, A T; Simão, E; Silva, L; Torres, G A

    2015-05-01

    Studies on the anatomy of Piper leaves demonstrate the presence of a subepidermal tissue distinct from the adjacent epidermis, which cells show thin walls and hyaline contents. Some authors consider such cells a hypodermal tissue, while others refer to them as components of a multiple epidermis. In this study, the nature of this subepidermal tissue was investigated through the analysis of leaf ontogeny in three Piper species. The analysis showed that the referred tissue originates from the ground meristem and, thus, should be considered a hypodermis. The studied species suggests that the role of the hypodermis would be to protect the photosynthetic apparatus from excess light, regulating the intensity of light reaching the chlorophyll parenchyma.

  2. Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae

    Directory of Open Access Journals (Sweden)

    João Henrique G. Lago

    2007-10-01

    Full Text Available Bioguided fractionation of the extracts from leaves of Piper mollicomum and Piper lhotzkyanum against the fungi Cladosporium cladosporioides and C. sphaerospermum afforded seven bioactive compounds, four being chromenes: methyl 2,2-dimethyl-2H-chromene-6-carboxylate, methyl 8-hydroxy-2,2-dimethyl-2H-chromene-6-carboxylate, 2-methyl-2-[4'-methyl-3'-pentenyl]-2H-1-benzopyran-6-carboxylic acid, 2,2-dimethyl-2H-chromene-6-carboxylic acid, one a dihydrochalcone: 2',6'-dihydroxy-4'-methoxydihydrochalcone, and two flavanones: 7-methoxy-5,4'-dihydroxy-flavanone and 7,4'-dimethoxy-5-hydroxy-flavanone. The structures of the bioactive isolated derivatives were elucidated by interpretation of their NMR data [¹H and 13C (BBD, DEPT 135º], and mass spectral data as well as by comparison with data described in the literature.

  3. Golden Heart of the Nature: Piper betle L.

    Directory of Open Access Journals (Sweden)

    Dr. K. A. Suri

    2013-03-01

    Full Text Available The heart shaped betel leaves are found in ancient Sanskrit texts, including Charaka, Sushruta Samhita and Astanga Hradayam. Piper betle L. have been used in chinese, Indian folk medicine for centuries. In this review, different research works related to Ayurvedic consequence, geographical distribution and cultivation, morphoanatomy, phytochemistry, biological activities, along with tradomedicinal uses which signify the tremendous potential of “Piper betle L.” to come out as Green medicine. The objective of it is to revels the potential effect of this plant in the development of therapeutically active herbal drugs against different microbial infections especially for oral cavity, which also gives the opportunity to pharmaceutical companies interested in formulation and production of natural product based drugs targeted towards specific aliments.

  4. Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Lago, Joao Henrique G. [Universidade Presbiteriana Mackenzie, Sao Paulo, SP (Brazil). Centro de Ciencias e Humanidades]. E-mail: joaolago@iq.usp.br; Young, Maria Claudia M. [Instituto de Botanica, Sao Paulo, SP (Brazil). Secao de Fisiologia e Bioquimica de Plantas; Reigada, Juliana B.; Soares, Marisi G.; Roesler, Bianca P.; Kato, Massuo J. [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Quimica

    2007-09-15

    Bioguided fractionation of the extracts from leaves of Piper mollicomum and Piper lhotzkyanum against the fungi Cladosporium cladosporioides and C. sphaerospermum afforded seven bioactive compounds, four being chromenes: methyl 2,2-dimethyl-2H-chromene-6-carboxylate, methyl 8-hydroxy-2,2-dimethyl-2H-chromene-6-carboxylate, 2-methyl-2-[4'-methyl-3'-pentenyl]-2H-1-benzopyrane-6-carboxylic acid, 2,2-dimethyl-2H-chromene-6-carboxylic acid, one a dihydrochalcone: 2',6'-dihydroxy-4'-methoxydihydrochalcone, and two flavanones: 7-methoxy-5,4'-dihydroxy-flavanone and 7,4'-dimethoxy-5-hydroxy-flavanone. The structures of the bioactive isolated derivatives were elucidated by interpretation of their NMR data [{sup 1}H and {sup 13}C (BBD, DEPT 135 deg)], and mass spectral data as well as by comparison with data described in the literature. (author)

  5. Chemical constituents of Piper betle Linn. (Piperaceae) roots.

    Science.gov (United States)

    Ghosh, K; Bhattacharya, T K

    2005-08-31

    Column chromatography of the alcoholic extract of Piper betle roots furnished aristololactam A-II and a new phenyl propene, characterized as 4-allyl resorcinol, while the petroleum-ether extract yielded a diketosteroid, viz. stigmast-4-en-3,6-dione. All these compounds were characterized by spectroscopic means. Isolation of these compounds from this source is being reported here for the first time.

  6. Chemical Constituents of Piper betle Linn. (Piperaceae Roots

    Directory of Open Access Journals (Sweden)

    T. Bhattacharya

    2005-08-01

    Full Text Available Column chromatography of the alcoholic extract of Piper betle roots furnished aristololactam A-II and a new phenyl propene, characterized as 4-allyl resorcinol, while the petroleum-ether extract yielded a diketosteroid, viz. stigmast-4-en-3,6-dione. All these compounds were characterized by spectroscopic means. Isolation of these compounds from this source is being reported here for the first time.

  7. Phenolic antibacterials from Piper betle in the prevention of halitosis.

    Science.gov (United States)

    Ramji, Niranjan; Ramji, Nivedita; Iyer, Ritu; Chandrasekaran, S

    2002-11-01

    Piper betle L. (Piperaceae) leaves which are traditionally used in India and China in the prevention of oral malodor was examined by bioassay-guided fractionation to yield allylpyrocatechol (APC) as the major active principle which showed promising activity against obligate oral anaerobes responsible for halitosis. The biological studies with APC indicated that the potential to reduce methylmercaptan and hydrogen sulfide was mainly due to the anti-microbial activity as established using dynamic in vitro models.

  8. Antimalarial Activity of Methanolic Leaf Extract of Piper betle L.

    OpenAIRE

    Amran, Adel A.; Rohela Mahmud; Zurainee M. Nor; Al-Mekhlafi, Hesham M; Al-Adhroey, Abdulelah H

    2010-01-01

    International audience; The need for new compounds active against malaria parasites is made more urgent by the rapid spread of drug-resistance to available antimalarial drugs. The crude methanol extract of Piper betle leaves (50-400 mg/kg) was investigated for its antimalarial activity against Plasmodium berghei (NK65) during early and established infections. The phytochemical and antioxidant potentials of the crude extract were evaluated to elucidate the possibilities of its antimalarial eff...

  9. Chemical Constituents of Piper betle Linn. (Piperaceae) Roots

    OpenAIRE

    Bhattacharya, T; Ghosh, K.

    2005-01-01

    Column chromatography of the alcoholic extract of Piper betle roots furnished aristololactam A-II and a new phenyl propene, characterized as 4-allyl resorcinol, while the petroleum-ether extract yielded a diketosteroid, viz. stigmast-4-en-3,6-dione. All these compounds were characterized by spectroscopic means. Isolation of these compounds from this source is being reported here for the first time.

  10. Two new ceramides from the stems of Piper betle L.

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Two new ceramides,(2S,3S,4R)-2-N-[(2'R)-2'-hydroxypentacosanoylamino]-nonacosane-1,3,4-triol(1) and(2S,3S,4R,8E)-2- N-[(2'R)-2'-hydroxytetracosanoylamino]-8-eicosylene-1,3,4-triol(2) have been isolated from the stems of Piper betle L.collected from Baoshan city of Yunnan Province in China.Their structures were determined by spectroscopic and chemical methods.

  11. A New Hydroxychavicol Dimer from the Roots of Piper betle

    OpenAIRE

    Huei-Yu Tu; Horng-Liang Lay; Chun-Chien Chien; Chwan-Fwu Lin; Tsong-Long Hwang

    2013-01-01

    A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

  12. A New Hydroxychavicol Dimer from the Roots of Piper betle

    Directory of Open Access Journals (Sweden)

    Huei-Yu Tu

    2013-02-01

    Full Text Available A new hydroxychavicol dimer, 2-(g'-hydroxychavicol-hydroxychavicol (1, was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2, aristololactam A II (3, aristololactam B II (4, piperolactam A (5 and cepharadione A (6. The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

  13. A new hydroxychavicol dimer from the roots of Piper betle.

    Science.gov (United States)

    Lin, Chwan-Fwu; Hwang, Tsong-Long; Chien, Chun-Chien; Tu, Huei-Yu; Lay, Horng-Liang

    2013-02-26

    A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

  14. ARISTOLACTAMA Y ESTERÓLES DEL TALLO DE Piper chiadoense

    Directory of Open Access Journals (Sweden)

    Luz Angela Peña O.

    2010-09-01

    Full Text Available Del extracto etanólico del tallo de Piper chiadoense Junker (Piperaceae fueron aislados por métodos cromatográficos la aristolactama identificada como lactama del ácido 10-amino-3,4-dimetoxifenantreno-l carboxílico (cepharanone B; campesterol; estigmasterol y B-sitosterol. Sus estructuras fueron determinadas por métodos espectroscópicos y por comparación con datos reportados en la literatura.

  15. Essential oil constituents of Piper cubeba L. fils. from Indonesia

    NARCIS (Netherlands)

    Bos, Rein; Woerdenbag, Herman J.; Kayser, Oliver; Quax, Wim J.; Ruslan, Komar; Elfami, [No Value

    2007-01-01

    The chemical composition of the essential oil of ripe berries (11.8% v/w) and leaves (0.9% v/w) of Piper cubeba L. fils. (Piperaceae) was investigated by GC and GUMS. Sabinene (9.1%), beta-elemene (9.4%), beta-caryophyllene (3.1%), epi-cubebol (4.3%), and cubebol (5.6%) were the main components of

  16. Essential oil constituents of Piper cubeba L. fils. from Indonesia

    NARCIS (Netherlands)

    Bos, Rein; Woerdenbag, Herman J.; Kayser, Oliver; Quax, Wim J.; Ruslan, Komar; Elfami, [No Value

    2007-01-01

    The chemical composition of the essential oil of ripe berries (11.8% v/w) and leaves (0.9% v/w) of Piper cubeba L. fils. (Piperaceae) was investigated by GC and GUMS. Sabinene (9.1%), beta-elemene (9.4%), beta-caryophyllene (3.1%), epi-cubebol (4.3%), and cubebol (5.6%) were the main components of t

  17. Boring and excavation technologies for Opalinus clay in the rock laboratories at Mont Terri; Techniques de forages et d'excavations dans les argiles à Opalinus, laboratoire souterrain du Mont Terri

    Energy Technology Data Exchange (ETDEWEB)

    Bossart, P.; Nussbaum, Ch. [Swiss Federal Office of Topography swisstopo, Wabern (Switzerland); Burrus, F. [Groupe Grands Travaux GGT, Porrentruy (Switzerland)

    2012-07-01

    This comprehensive article discusses the work done since 1996 at the rock laboratories at Mont Terri in the Swiss Jura Mountains. The work being done by fifteen international partners on the characterisation of the Opalinus clay with regard to its geological, hydro-geological, geochemical and geotechnical characteristics is reported on. Various methods of drilling are described that are able to preserve any tectonic crevices in the rock. Drilling under special conditions, including the use of nitrogen and argon atmospheres to prevent bacterial contamination, is looked at, as are the methods used in tunnelling without having to use water.

  18. Antioxidant, antitubercular and cytotoxic activities of Piper imperiale.

    Science.gov (United States)

    Diaz, Luis E; Munoz, Diego R; Prieto, Rosa E; Cuervo, Sergio A; Gonzalez, Diego L; Guzman, Juan D; Bhakta, Sanjib

    2012-04-05

    Phenolic compounds are widely distributed in Nature and act as pharmacologically active constituents in many herbal medicines. They have multiple biological properties, most notably antioxidant, antibacterial and cytotoxic activities. In the present study an attempt to correlate the phenolic composition of leaf, flower and wood extracts of Piper imperiale, with antioxidant, antitubercular and cytotoxic activities was undertaken. The total phenol content ranged from 1.98 to 6.94 mg GAE/gDW among ethanolic extracts, and gallic acid, catechin, epicatechin, ferulic acid, resveratrol and quercetin were identified and quantified by HPLC. DPPH and ABTS assays showed high antioxidant activity of the leaf extract (EC(50ABTS) = 15.6 µg/mL, EC(50DPPH) = 27.3 µg/mL) with EC₅₀ in the same order of magnitude as the hydroxyquinone (EC(50ABTS) = 10.2 µg/mL, EC(50DPPH) = 15.7 µg/mL). The flower extract showed strong antimicrobial activity against Mycobacterium tuberculosis H₃₇Rv. All the extracts exhibited dose-dependent cytotoxic effects against MCF-7 cancer cells. This is the first time that a Piper extract has been found to be highly active against M. tuberculosis. This study shows the biological potential of Piper imperiale extracts and gives way to bio-guided studies with well-defined biological activities.

  19. Antimalarial Activity of Methanolic Leaf Extract of Piper betle L.

    Directory of Open Access Journals (Sweden)

    Adel A. Amran

    2010-12-01

    Full Text Available The need for new compounds active against malaria parasites is made more urgent by the rapid spread of drug-resistance to available antimalarial drugs. The crude methanol extract of Piper betle leaves (50–400 mg/kg was investigated for its antimalarial activity against Plasmodium berghei (NK65 during early and established infections. The phytochemical and antioxidant potentials of the crude extract were evaluated to elucidate the possibilities of its antimalarial effects. The safety of the extract was also investigated in ICR mice of both sexes by the acute oral toxicity limit test. The leaf extract demonstrated significant (P < 0.05 schizonticidal activity in all three antimalarial evaluation models. Phytochemical screening showed that the leaf extract contains some vital antiplasmodial chemical constituents. The extract also exhibited a potent ability to scavenge the free radicals. The results of acute toxicity showed that the methanol extract of Piper betle leaves is toxicologically safe by oral administration. The results suggest that the Malaysian folklorical medicinal application of the extract of Piper betle leaf has a pharmacological basis.

  20. Antioxidant, Antitubercular and Cytotoxic Activities of Piper imperiale

    Directory of Open Access Journals (Sweden)

    Sanjib Bhakta

    2012-04-01

    Full Text Available Phenolic compounds are widely distributed in Nature and act as pharmacologically active constituents in many herbal medicines. They have multiple biological properties, most notably antioxidant, antibacterial and cytotoxic activities. In the present study an attempt to correlate the phenolic composition of leaf, flower and wood extracts of Piper imperiale, with antioxidant, antitubercular and cytotoxic activities was undertaken. The total phenol content ranged from 1.98 to 6.94 mg GAE/gDW among ethanolic extracts, and gallic acid, catechin, epicatechin, ferulic acid, resveratrol and quercetin were identified and quantified by HPLC. DPPH and ABTS assays showed high antioxidant activity of the leaf extract (EC50ABTS = 15.6 µg/mL, EC50DPPH = 27.3 µg/mL with EC50 in the same order of magnitude as the hydroxyquinone (EC50ABTS = 10.2 µg/mL, EC50DPPH = 15.7 µg/mL. The flower extract showed strong antimicrobial activity against Mycobacterium tuberculosis H37Rv. All the extracts exhibited dose-dependent cytotoxic effects against MCF-7 cancer cells. This is the first time that a Piper extract has been found to be highly active against M. tuberculosis. This study shows the biological potential of Piper imperiale extracts and gives way to bio-guided studies with well-defined biological activities.

  1. Piper nigrum, Piper betle and Gnetum gnemon--natural food sources with anti-quorum sensing properties.

    Science.gov (United States)

    Tan, Li Ying; Yin, Wai-Fong; Chan, Kok-Gan

    2013-03-20

    Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS) properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [pSB1075] and Chromobacterium violaceum CV026. It was found that the extracts of these three plants have anti-QS ability. Interestingly, the hexane, chloroform and methanol extracts from P. betle showed the most potent anti-QS activity as judged by the bioassays. Since there is a variety of plants that serve as food sources in Malaysia that have yet to be tested for anti-QS activity, future work should focus on identification of these plants and isolation of the anti-QS compounds.

  2. Analysis of tectonic structures and excavation induced fractures in the Opalinus Clay, Mont Terri underground rock laboratory (Switzerland)

    Energy Technology Data Exchange (ETDEWEB)

    Nussbaum, Ch.; Bossart, P. [Federal Office of Topography swisstopo, Wabern (Switzerland); Amann, F. [Swiss Federal Institute of Technology Zuerich, Zuerich (Switzerland); Aubourg, Ch. [Laboratoire des fluides complexes et leurs reservoirs, Centre National de la Recherche Scientitfique CNRS, Universite de Pau, Pau (France)

    2011-09-15

    Excavated in the Opalinus Clay formation, the Mont Terri underground rock laboratory in the Jura Mountains of NW Switzerland is an important international test site for researching argillaceous formations, particularly in the context of deep geological disposal of radioactive waste. The rock laboratory is intersected by naturally formed tectonic structures, as well as artificial fractures primarily formed as a consequence of tunnel excavation and the associated stress redistribution. The description and characterisation of tectonic and artificial structures is, in many cases, of key importance for interpreting the results of the various in situ experiments conducted in the rock laboratory. Systematic small-scale mapping of the tunnel walls and floor, and adjacent niches, provides basic information about the geometry and the kinematics of the geological fractures intersecting the underground laboratory. A compilation of all tectonic structures identified is presented in this paper. The underground laboratory is located in the backlimb of the Mont Terri anticline, a NNW-vergent imbricate fault-bend fold, which is characterised by a pronounced along-strike asymmetry resulting from variously oriented inherited faults. The total shortening accommodated by this structure was estimated by mass (area) balancing to be approximately 2.1 km. The Mont Terri area is significantly affected by N- to NNE-striking normal faults of the Eo-Oligocene Rhine-Bresse transfer zone and by ENE-striking faults of Late Variscan age. Depending on their orientation with respect to the transport direction towards the NNW, these faults served as oblique and frontal ramps during the subsequent Jura thrusting in the Late Miocene. The various fault systems identified in the underground rock laboratory clearly correlate with the regional-scale structures. In addition to classical structural analysis, the anisotropy of magnetic susceptibility was measured to determine the magnetic fabric and strain

  3. Genetic diversity of "Pimenta Longa" genotypes (Piper spp., Piperaceae of the Embrapa Acre germplasm collection

    Directory of Open Access Journals (Sweden)

    Lúcia Helena de Oliveira Wadt

    2004-01-01

    Full Text Available The commonly known Pimenta longa is a commercially valuable natural resource found wild in Acre, Brazil. Specifically, three Piperaceae species with contested taxonomic status were studied, Piper hispidinervum, Piper aduncum, and Piper hispidum, to assesses the inter- and intra-specific genetic relationship of 49 Piper genotypes kept in the Pimenta longa germplasm collection at Embrapa Acre, using sixty six Random Amplified Polymorphic DNA (RAPD markers. The DNA polymorphism level detected was high (96.97%, but the marker frequencies for each species showed polymorphism levels of 79.4% for Piper hispidinervum and 5.3% for P. aduncum. The genetic similarity clustering analysis resulted in three distinct groups corresponding to Piper hispidinervum, Piper aduncum, and Piper hispidum. Four and nine characteristic RAPD markers were identified for P. hispidinervum and P. aduncum, respectively, supporting the existence of two separate species. However, six genotypes collected in Tarauacá county formed a distinct subgroup within the P. hispidinervum group and may be considered as an ecotype of this species or an intermediate between the P. hispidinervum and P. aduncum groups. More extensive sampling of both P. hispidinervum and P. aduncum populations throughout the region are needed to further establish their relation and its implication for breeding efforts.

  4. 75 FR 81417 - Airworthiness Directives; Piper Aircraft, Inc. Model PA-28-161 Airplanes

    Science.gov (United States)

    2010-12-28

    ...-057-AD; Amendment 39-16543; AD 2010-26-04] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc...): 2010-26-04 Piper Aircraft, Inc: Amendment 39-16543; Docket No. FAA- 2010-1006; Directorate Identifier... alternative GmbH Supplement replacement times may be Airplane approved for this part. Maintenance Manual...

  5. The invasive shrub Piper aduncum in Papua New Guinea: a review

    NARCIS (Netherlands)

    Hartemink, A.E.

    2010-01-01

    HARTEMINK AE. 2010. The invasive shrub Piper aduneum in Papua New Guinea: a review. Piper aduncum is a shrub native to Central America. It is found in most Central and South American countries and also in the Caribbean and southern Florida (USA). In Asia and the Pacific, P aduncum occurs in

  6. The invasive shrub Piper aduncum in Papua New Guinea: a review

    NARCIS (Netherlands)

    Hartemink, A.E.

    2010-01-01

    HARTEMINK AE. 2010. The invasive shrub Piper aduneum in Papua New Guinea: a review. Piper aduncum is a shrub native to Central America. It is found in most Central and South American countries and also in the Caribbean and southern Florida (USA). In Asia and the Pacific, P aduncum occurs in Indonesi

  7. Supervisor self-disclosure: supervisees' experiences and perspectives.

    Science.gov (United States)

    Knox, Sarah; Edwards, Lisa M; Hess, Shirley A; Hill, Clara E

    2011-12-01

    Twelve graduate-level supervisees were interviewed regarding their experiences of supervisor self-disclosure (SRSD); data were analyzed using consensual qualitative research. When describing a specific SRSD experience, supervisees reported a range of antecedents (e.g., difficult clinical situation, self-doubt, tension in supervision relationship) followed by supervisor disclosures about clinical experiences or personal information. Supervisees perceived that their supervisors disclosed primarily to normalize, but also to build rapport and to instruct. The SRSDs had mostly positive effects (e.g., normalization), though some negative effects (e.g., deleterious impact on supervision relationship) were reported. Implications of these findings for supervision, training, and research are addressed.

  8. Clay under the magnifier. Scientists are investigating the properties of claystone in the international Mont Terri rock laboratory; Ton unter der Lupe. Wissenschaftler erforschen die Eigenschaften von Tongestein im internationalen Felslabor Mont Terri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    In the present report of the Institute for Geosciences and Natural Resources whose activities and projects are presented. Among the issues: securing supplies of raw materials; Receive livelihoods; Develop and link Knowledge of Geosciences. Use deep underground, protected against geological hazards, assist developing countries, monitor Comprehensive Nuclear Test Ban. Described are also studies of clay-mineral processes in barrier systems, studies of the long-term safety of the Morsleben repository, as well as international research of clay in the Swiss Mont Terri Rock Loboratory on the suitability of claystone as repository for secure high-level radioactive waste. [German] Im vorliegenden Report der Bundesanstalt fuer Geowissenschaften und Rohstoffe werden deren Aktivitaeten und Projekte dargestellt. Zu den Aspekten: Rohstoffversorgung sichern; Lebensgrundlagen erhalten; Geowissen entwickeln und vernetzen. Den tiefen Untergrund nutzen, vor Geogefahren schuetzen, Entwicklungslaender unterstuetzen, Kernwaffenteststopp ueberwachen. Beschrieben werden dabei auch Untersuchungen tonmineralischer Prozesse in Barrieresystemen, Untersuchungen zur Langzeitsicherheit des Endlagers Morsleben, sowie internationale Forschungen im Tongestein des Schweizer Felslabors Mont Terri zur Eignung von Tongestein als sicheres Endlager fuer hochradioaktive Abfallstoffe.

  9. Anti-inflammatory and antioxidant properties of Piper species: a perspective from screening to molecular mechanisms.

    Science.gov (United States)

    Kumar, Sarvesh; Malhotra, Shashwat; Prasad, Ashok K; Van der Eycken, Erik V; Bracke, Marc E; Stetler-Stevenson, William G; Parmar, Virinder S; Ghosh, Balaram

    2015-01-01

    Identifying novel therapeutic agents from natural sources and their possible intervention studies has been one of the major areas in biomedical research in recent years. Piper species are highly important - commercially, economically and medicinally. Our groups have been working for more than two decades on the identification and characterization of novel therapeutic lead molecules from Piper species. We have extensively studied the biological activities of various extracts of Piper longum and Piper galeatum, and identified and characterized novel molecules from these species. Using synthetic chemistry, various functional groups of the lead molecules were modified and structure activity relationship (SAR) studies identified synthetic molecules with better efficacy and lower IC50 values. Moreover, the mechanisms of actions of some of these molecules were studied at the molecular level. The objective of this review is to summarize experimental data published from our laboratories and others on antioxidant and anti-inflammatory potentials of Piper species and their chemical constituents.

  10. Piper kelleyi, a hotspot of ecological interactions and a new species from Ecuador and Peru

    Directory of Open Access Journals (Sweden)

    Eric Tepe

    2014-02-01

    Full Text Available We describe Piper kelleyi sp. nov., a new species from the eastern Andes of Ecuador and Peru, named in honor of Dr. Walter Almond Kelley. Piper kelleyi is a member of the Macrostachys clade of the genus Piper and supports a rich community of generalist and specialist herbivores, their predators and parasitoids, as well as commensalistic earwigs, and mutualistic ants. This new species was recognized as part of an ecological study of phytochemically mediated relationships between plants, herbivores, predators, and parasitoids. Compared to over 100 other Piper species surveyed, Piper kelleyi supports the largest community of specialist herbivores and parasitoids observed to date.

  11. Supervisors' perspective on medical thesis projects and dropout rates: survey among thesis supervisors at a large German university hospital.

    Science.gov (United States)

    Can, Elif; Richter, Felicitas; Valchanova, Ralitsa; Dewey, Marc

    2016-10-14

    To identify underlying causes for failure of medical thesis projects and the constantly high drop-out rate in Germany from the supervisors' perspective and to compare the results with the students' perspective. Cross-sectional survey. Online questionnaire for survey of medical thesis supervisors among the staff of Charité-Universitätsmedizin Berlin, Germany. Published, earlier longitudinal survey among students for comparison. 1069 thesis supervisors participated. Data are presented using descriptive statistics, and the χ(2) test served to compare the results among supervisors with the earlier data from the longitudinal survey of doctoral students. Not applicable. This survey is an observational study. Of 3653 potential participants, 1069 (29.3%) supervising 3744 doctoral candidates participated in the study. Supervisors considered themselves to be highly motivated and to offer adequate supervision. On the other hand, 87% stated that they did not feel well prepared for thesis supervision. Supervisors gave lack of timeliness of doctoral students and personal differences (p=0.024 and p=0.001) as the main reasons for terminating thesis projects. Doctoral students predominantly mentioned methodological problems and difficult subjects as critical issues (p=0.001 and pthesis supervisors and medical students feel ill prepared for their roles in the process of a medical dissertation. Contradictory reasons for terminating medical thesis projects based on supervisors' and students' self-assessment suggest a lack of communication and true scientific collaboration between supervisors and doctoral students as the major underlying issue that requires resolution. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  12. PENGARUH DUKUNGAN SUPERVISOR DAN PEMBERDAYAAN TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Tinjung Desy Nursanti

    2014-07-01

    Full Text Available Study aims to determine and obtain a clear picture of supportive supervisor, empowerment, and organizational citizenship behavior; and to determine the impact of supportive supervisor and empowerment towards organizational citizenship behavior of employees in PT Setia Makmur Cemerlang. Research used explanatory survey method, while the sample was taken from employees of the company. Research instrument (questionnaires was used as primary data collection to explain the causal relationship between supportive supervisor and empowerment on organizational citizenship behavior of employees in PT Setia Makmur Cemerlang. Analysis used simple linear regression and multiple linear regression method. Result of this study shows that there is significant influence between supportive supervisor and empowerment towards organizational citizenship behavior.

  13. Pengaruh Dukungan Supervisor dan Pemberdayaan Terhadap Organizational Citizenship Behavior

    Directory of Open Access Journals (Sweden)

    Tinjung Desy Nursanti

    2014-05-01

    Full Text Available Study aims to determine and obtain a clear picture of supportive supervisor, empowerment, and organizational citizenship behavior; and to determine the impact of supportive supervisor and empowerment towards organizational citizenship behavior of employees in PT Setia Makmur Cemerlang. Research used explanatory survey method, while the sample was taken from employees of the company. Research instrument (questionnaires was used as primary data collection to explain the causal relationship between supportive supervisor and empowerment on organizational citizenship behavior of employees in PT Setia Makmur Cemerlang. Analysis used simple linear regression and multiple linear regression method. Result of this study shows that there is significant influence between supportive supervisor and empowerment towards organizational citizenship behavior.

  14. Supervisor behaviour and its associations with employees' health in Europe.

    Science.gov (United States)

    Montano, Diego

    2016-02-01

    To estimate the magnitude of the associations between different facets of supervisor behaviour and several health-related outcomes, and to assess whether these associations are mediated by known occupational health factors. Cross-sectional data from the European Working Conditions Survey were analysed by generalised linear mixed models (n = 32,770). Six regression models were estimated. Dependent variables include musculoskeletal (upper body, lower limbs, backache) and psychosomatic symptoms (stress and self-assessed general health). Independent variables correspond to several facets of supervisor behaviours such as supervisor support, feedback on work, ability to solve conflicts, encouragement to participate in decisions, and known occupational risk and protective factors. Even though supervisor behaviour is mediated by several known occupational risk factors, it still accounts for a substantial proportion of explained variance. The order of magnitude of associations was comparable to the strength of associations of known occupational risk factors. Odds ratios vary from 0.79 95% CI [0.73-0.86] to 1.12 95% CI [0.97-1.29] for dichotomous dependent variables. Regression coefficients vary from -0.22 95% CI [-0.28 to -0.17] to 0.07 95% CI [0.04-0.10] for metric dependent variables. Results suggest that good conflict solving skills, supervisor's work-planning ability, and a participative leadership style have the strongest predictive power regarding all health-related outcomes considered. Supervisor behaviour seems to play a non-negligible role from an occupational health perspective concerning the prevalence of musculoskeletal and psychosomatic symptoms. Results suggest that supervisor behaviour should be routinely assessed and monitored, especially among occupational groups reporting a lower quality of supervisor behaviours.

  15. Administrative Supervisors: A Qualitative Exploration of Their Perceived Role.

    Science.gov (United States)

    Weaver, Susan H; Lindgren, Teri

    2016-01-01

    The administrative supervisor, who is the nurse manager present on the night and weekend shifts, can be found in hospitals throughout the United States. Yet, very little research has been published about this role on weekend and night shifts in acute care hospitals. The objective of this qualitative research study was to gain a better understanding of the administrative supervisor role. In-depth interviews with administrative supervisors were conducted at acute care hospitals in the mid-Atlantic region of the United States. Thematic analysis was used to reduce the data and identify codes and themes. Administrative supervisors experience and described their role within a "different" hospital world on weekends and at night. The administrative supervisors consistently stated that they oversee and are responsible for staffing and patient flow, crisis management, and management support for the staff. That administrative supervision is a challenging position for nurses is particularly evident as researchers seek to obtain a better understanding of how nurse leaders make a difference. This research delineates these different supervisor role responsibilities to provide a better understanding of management during the "off-shift." Nurse leaders can utilize this information to assist in justifying the need for this shift management role at their institutions.

  16. Exploring Supervisor-Related Job Resources as Mediators between Supervisor Conflict and Job Attitudes in Hospital Employees

    Directory of Open Access Journals (Sweden)

    Achim Elfering

    2017-03-01

    Conclusion: Conflicts with supervisors are likely to reduce job resources and in turn to lower job attitudes. Work design in hospitals should, therefore, address interpersonal working conditions and conflict management in leadership development.

  17. Efficient DNA barcode regions for classifying Piper species (Piperaceae

    Directory of Open Access Journals (Sweden)

    Arunrat Chaveerach

    2016-09-01

    Full Text Available Piper species are used for spices, in traditional and processed forms of medicines, in cosmetic compounds, in cultural activities and insecticides. Here barcode analysis was performed for identification of plant parts, young plants and modified forms of plants. Thirty-six Piper species were collected and the three barcode regions, matK, rbcL and psbA-trnH spacer, were amplified, sequenced and aligned to determine their genetic distances. For intraspecific genetic distances, the most effective values for the species identification ranged from no difference to very low distance values. However, P. betle had the highest values at 0.386 for the matK region. This finding may be due to P. betle being an economic and cultivated species, and thus is supported with growth factors, which may have affected its genetic distance. The interspecific genetic distances that were most effective for identification of different species were from the matK region and ranged from a low of 0.002 in 27 paired species to a high of 0.486. Eight species pairs, P. kraense and P. dominantinervium, P. magnibaccum and P. kraense, P. phuwuaense and P. dominantinervium, P. phuwuaense and P. kraense, P. pilobracteatum and P. dominantinervium, P. pilobracteatum and P. kraense, P. pilobracteatum and P. phuwuaense and P. sylvestre and P. polysyphonum, that presented a genetic distance of 0.000 and were identified by independently using each of the other two regions. Concisely, these three barcode regions are powerful for further efficient identification of the 36 Piper species.

  18. The views of teachers about the ethical behaviors of Educational Supervisors and Ministry’s Supervisors

    Directory of Open Access Journals (Sweden)

    Nurhayat Çelebi

    2012-08-01

    Full Text Available The aim of this research has to find out primary and high school teachers’ perceptions of supervisors’ ethical behavior. The model of the research was descriptive survey. The sampling of research was formed by 112 teachers working in Avcılar, Istanbul. 52 of those teachers are working in primary schools and the rest (60 were working in high schools. The measurement tool used in this research was developed by Akyıldız (2007 to measure teachers’ perceptions of ethical behavior. The scale has 37 items and formed as 5 items Likert type. Internal consistency of the scale was found .95. Factorial sub-dimensions’ item total correlation coefficients were between .75 and .70. The methods used in analysis process are factorial analysis, independent samples t test, two-way ANOVA, independent samples non-parametric Kruskal Wallis H, Mann Whitney-U. According to the results of factorial analysis, teachers’ perceptions of ethical behaviors were formed within 5 groups. These dimensions are: “professional moral”, “common sense”, “honesty”, “objectivity”, “responsibility”. Teachers’ perceptions were found out meaningfully different considering school type but didn’t different according to gender. Also, each factorial sub-dimension was examined and “objectivity, honesty and discourse ethics” sub-dimensions were found different according to job experience and honesty according to educational level. According to the results of the research, teachers found ministry’s supervisors more positive than educational supervisors

  19. Antifungal activity of natural and synthetic amides from Piper species

    Energy Technology Data Exchange (ETDEWEB)

    Marques, Joaquim V.; Oliveira, Alberto de; Kato, Massuo J., E-mail: majokato@iq.usp.b [Universidade de Sao Paulo (IQ/USP), SP (Brazil). Inst. de Quimica; Raggi, Ludmila; Young, Maria C. [Instituto de Botanica, Sao Paulo, SP (Brazil). Secao de Fisiologia e Bioquimica de Plantas

    2010-07-01

    The antifungal leaves extract from Piper scutifolium was submitted to bioactivity-guided chromatographic separation against Cladosporium cladosporioides and C. sphaerospermum yielding piperine, piperlonguminine and corcovadine as the active principles which displayed a detection limit of 1 {mu}g. Structure-activity relationships were investigated with the preparation of twelve analogs having differences in the number of unsaturations, aromatic ring substituents and in the amide moiety. Analogs having a single double-bond and no substituent in the aromatic ring displayed higher activity, while N,N,-diethyl analogs displayed higher dose-dependent activity. (author)

  20. Three new compounds from Piper montealegreanum Yuncker (Piperaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Harley da S.; Souza, Maria de F.V. de; Chaves, Maria C. de O., E-mail: cchaves@ltf.ufpb.b [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Lab. de Tecnologia Farmaceutica

    2011-07-01

    Three new compounds: two flavonoids [(S)-8-formyl-3',5-dihydroxy-7-methoxy-6-methylflavanone (1) and 3'-formyl-3,4',6'-trihydroxy-2'-methoxy-5'-methylchalcone (2)] and one phenylpropanoid [ethyl 3,4-methylenedioxy-5-methoxy-7,8-dihydrocinnamate (3)] were isolated from dried branches of Piper montealegreanum. Their structures were established by UV, IR, MS, 1D and 2D ({sup 1}H and {sup 13}C) NMR spectroscopic techniques, besides interpretation of spectral data ({sup 1}H and {sup 13}C NMR) of methylated derivatives of 1 and 2 compounds. (author)

  1. Phytochemical studies on the seed extract of Piper nigrum Linn.

    Science.gov (United States)

    Rasheed, Munawwer; Afshan, Farhana; Tariq, Rajput M; Siddiqui, Bina S; Gulzar, Tahsin; Mahmood, Azhar; Begum, Sabira; Khan, Bushra

    2005-10-01

    The petroleum ether extract of dried ground seeds of Piper nigrum Linn. and some column fractions of this extract were subjected to GC and GC-MS analysis, resulting in the identification of fourteen compounds (1-14) by using NIST Mass spectral search program 1998 and the Kovat's retention indices. Ten of the compounds (1, 2, 4-12) are reported for the first time from this plant. All the fractions showed insecticidal activity against the fourth instar larvae of Aedes aegypti and against the fourth instar larvae of Anopheles stephensi Liston, determined by the WHO method.

  2. Abusive supervision and workload demands from supervisors: exploring two types of supervisor-related stressors and their association with strain.

    Science.gov (United States)

    Wu, Tsung-Yu; Hu, Changya; Yang, Chun-Chi

    2013-08-01

    Our study aimed to identify two types of stressors from supervisors: abusive supervision (AS) and workload demands from supervisors (WDS). AS reflects the relationship dimension of supervisor-related stressors, and WDS reflects the task dimension of supervisor-related stressors. In Study 1, we attempted to distinguish between AS and WDS. The results of confirmatory factor analysis showed that AS and WDS are two distinct dimensions of supervisor-related stressors. In Study 2, we utilized job demands-resources model and investigated whether AS and WDS can uniquely predict subordinates' emotional exhaustion (EE). We also explored whether perceived job characteristics (PJCs) have differential moderating effects on the relationships between the two dimensions of supervisor-related stressors (AS and WDS) and EE. Consistent with our predictions, the results showed that both AS and WDS have incremental predictive effects on EE after controlling for the effect of the other. The results also revealed that PJCs weaken the WDS-EE relationship, not the AS-EE relationship. We discussed the theoretical and practical implications at the end.

  3. Associations of Work Stress, Supervisor Unfairness, and Supervisor Inability to Speak Spanish with Occupational Injury among Latino Farmworkers.

    Science.gov (United States)

    Clouser, Jessica Miller; Bush, Ashley; Gan, Wenqi; Swanberg, Jennifer

    2017-06-22

    Little is known about how psychosocial work factors such as work stress, supervisor fairness, and language barriers affect risk of occupational injury among Latino farmworkers. This study attempts to address these questions. Surveys were administered via interviews to 225 Latino thoroughbred farmworkers. Multivariable logistic regression analyses were performed to calculate odds ratios (OR) and 95% confidence intervals (CI) of occupational injury in the past year in relation to occupational characteristics. Work stress (OR 6.70, 95% CI 1.84-24.31), supervisor unfairness (OR 3.34, 95% CI 1.14-9.73), longer tenure at farm (OR 2.67, 95% CI 1.13-6.34), and supervisor inability to speak Spanish (OR 2.29, 95% CI 1.05-5.00) were significantly associated with increased odds of occupational injury. Due to the associations between work stress, supervisor unfairness, supervisor inability to speak Spanish and injury, supervisor training to improve Spanish language ability and equitable management practices is merited. Future research is needed to understand the antecedents of work stress for Latino farmworkers.

  4. MOECSW trains master trainers and supervisors.

    Science.gov (United States)

    1995-01-01

    The Ministry of Education, Culture and Social Welfare (MOECSW), as part of the Population Education Programs (formal and informal), undertook a series of training programs to upgrade the knowledge and skills of master trainers, supervisors, and resource persons. As part of the Population Education in the Formal School Sector Project (NEP/93/P01), under the Curriculum Development Centre five training courses were organized to train 220 master trainers. Under the "Three Steps Training Strategy," these 220 master trainers would teach 825 secondary school headmasters who would reach 2025 secondary school teachers. The training courses were held in Dhangadi, April 23-27, 1995; in Pokhara, April 2-7; and in Biratnagar, February 20-24. The areas covered included: 1) the pedagogical aspect of population education (content, scope, objectives, nature, teaching methodologies); 2) demography and population dynamics (composition, distribution and density, sources of population data, demographic transition, consequences and determinants of population growth); 3) family life and adolescence and human sexuality education, including acquired immunodeficiency syndrome (AIDS) education; 4) maternal and child health, and family planning; 5) environment; and 6) population policy and programs. As part of the Population Education Programme (NEP/93/P08), a Master Trainers Training Workshop was held in Makwanpur, March 26-28, 1995. These master trainers would train trainers who would train the facilitators and teachers at learning centers for adult learners under the literacy and post literacy programs. This course focused on the approaches and strategies for integrating population education in development programs, and non-formal education, adult literacy, post literacy, and out-of-school children programs. Dr. D. de Rebello and Mr. S. Hutabarat, CST Advisors on Population Education, organized the training courses and served as resource persons.

  5. The Fair Use of Trademark Viewed from the "Playboy v. Terri Welles" Case%从"Playboy"公司诉"Terri Welles"案看商标的合理使用

    Institute of Scientific and Technical Information of China (English)

    李娟

    2002-01-01

    @@ 1999年12月1日,美国加利福尼亚地区法院对"Playbob"公司诉"Terri Welles"女士商标侵权一案做出了有利于被告的简易裁决,双方对此未提出上诉.由于我国的知识产权法未对商标的合理使用问题做出规定,因此,本文拟在对该案进行介绍的基础上,分析商标的合理使用问题,以期对我国知识产权法的理论与实践有所借鉴.

  6. Analysis of genetic diversity of certain species of Piper using RAPD-based molecular markers.

    Science.gov (United States)

    Chowdhury, Utpal; Tanti, Bhaben; Rethy, Parakkal; Gajurel, Padma Raj

    2014-09-01

    The utility of RAPD markers in assessing genetic diversity and phenetic relationships of six different species of Piper from Northeast India was investigated. Polymerase chain reaction (PCR) with four arbitrary 10-mer oligonucleotide primers applied to the six species produced a total of 195 marker bands, of which, 159 were polymorphic. On average, six RAPD fragments were amplified per reaction. In the UPGMA phenetic dendrogram based on Jaccard's coefficient, the different accessions of Piper showed a high level of genetic variation. This study may be useful in identifying diverse genetic stocks of Piper, which may then be conserved on a priority basis.

  7. Anti lipid peroxidation activity of Piper trioicum Roxb. and Physalis minima L. extracts.

    Science.gov (United States)

    Dinakaran, Sathis Kumar; Saraswathi, Narasimha Raju; Nalini, Venkata Rama Rao; Srisudharson; Bodanapu, Venkat Ram Reddy; Avasarala, Harani; Banji, David

    2011-07-01

    Attempt has been made to evaluate free radical scavenging activity of ethanolic extract of Piper trioicum Roxb. and Physalis minima L. individually. In this study goat liver has been used as lipid source. This in vitro evaluation was done by measuring the malondialdehyde (MDA) of tissue homogenates. The results suggest that the ethanolic extract of the Piper trioicum Roxb. and Physalis minima L. has the ability to suppress the lipid peroxidation and it was also found that Piper trioicum Roxb. extract has more activity than Physalis minima L. extract.

  8. Emerging technologies for sustainable irrigation – a tribute to the career of Terry Howell, Sr. Selected papers from the 2015 ASABE and IA irrigation symposium

    Science.gov (United States)

    This article is an introduction to the “Emerging Technologies in Sustainable Irrigation – A Tribute to the Career of Terry Howell, Sr.” Special Collection in this issue of Transactions ASABE and the next issue of Applied Engineering in Agriculture, consisting of 15 articles selected from 62 papers a...

  9. Antiherbivore prenylated benzoic acid derivatives from Piper kelleyi.

    Science.gov (United States)

    Jeffrey, Christopher S; Leonard, Michael D; Glassmire, Andrea E; Dodson, Craig D; Richards, Lora A; Kato, Massuo J; Dyer, Lee A

    2014-01-24

    The known prenylated benzoic acid derivative 3-geranyl-4-hydroxy-5-(3″,3″-dimethylallyl)benzoic acid (1) and two new chromane natural products were isolated from the methanolic extract of the leaves of Piper kelleyi Tepe (Piperaceae), a midcanopy tropical shrub that grows in lower montane rain forests in Ecuador and Peru. Structure determination using 1D and 2D NMR analysis led to the structure of the chromene 2 and to the reassignment of the structure of cumanensic acid as 4, an isomeric chromene previously isolated from Piper gaudichaudianum. The structure and relative configuration of new chromane 3 was determined using 1D and 2D NMR spectroscopic analysis and was found to be racemic by ECD spectropolarimetry. The biological activity of 1-3 was evaluated against a lab colony of the generalist caterpillar Spodoptera exigua (Noctuidae), and low concentrations of 2 and 3 were found to significantly reduce fitness. Further consideration of the biosynthetic relationship of the three compounds led to the proposal that 1 is converted to 2 via an oxidative process, whereas 3 is produced through hetero-[4+2] dimerization of a quinone methide derived from the chromene 2.

  10. Volatile Constituents of Three Piper Species from Vietnam.

    Science.gov (United States)

    Hieua, Le D; Hoic, Tran M; Thangda, Tran D; Ogunwande, Isiaka A

    2015-11-01

    The chemical compositions of the essential oils obtained by hydrodistillation of three Piper plants grown in Vietnam are reported. The analysis was achieved by means of gas chromatography with flame ionization detection (GC-FID) and gas chromatography coupled with mass spectrometry (GC-MS). The main constituents of the leaf oil of Piper majusculum Blume were β-caryophyllene (20.7%), germacrene D (18.6%) and β-elemene (11.3%). The quantitatively significant compounds of the volatile oils of P. harmandii C. DC were sabinene (leaves, 14.5%; stems, 16.2%), benzyl benzoate (leaves, 20.0%; stems, 29.40%) and benzyl salicylate (leaves, 14.1%; stems, 24.3%). Also, α-cadinol (17.0%) was identified in large proportion in the leaf oil. However, sabinene (leaves, 17.9%; stems, 13.5%), benzyl benzoate (leaves, 20.5%; stems, 32.5%) and β-eudesmol (leaves, 13.8%; stems, 8.4%) were the main constituents of P. brevicaule C. DC. This is the first report on the volatile constituents of both P. harmandii and P. brevicaule.

  11. Antioxidative and antiplatelet effects of aqueous inflorescence Piper betle extract.

    Science.gov (United States)

    Lei, Daniel; Chan, Chiu-Po; Wang, Ying-Jan; Wang, Tong-Mei; Lin, Bor-Ru; Huang, Chun-Hsun; Lee, Jang-Jaer; Chen, Hsin-Ming; Jeng, Jiiang-Huei; Chang, Mei-Chi

    2003-03-26

    Piper betle, belonging to the Piperaceae family, is a tropical plant, and its leaf and inflorescence are popularly consumed by betel quid (BQ) chewers in Taiwan and many other South and Southeast Asian countries. However, little is known about the biochemical properties of inflorescence Piper betle (IPB) toward reactive oxygen species (ROS) and platelet functions. In the present work, aqueous IPB extract was shown to be a scavenger of H(2)O(2), superoxide radical, and hydroxyl radical with a 50% inhibitory concentration (IC(50)) of about 80, 28, and 73 microg/mL, respectively. IPB extract also prevented the hydroxyl radical induced PUC18 plasmid DNA breaks at concentrations higher than 40 microg/mL. Since ROS are crucial for platelet aggregation, we further found that IPB extract also inhibited the arachidonic acid (AA) induced and collagen-induced platelet aggregation, with an IC(50) of 207 and 335 microg/mL, respectively. IPB extract also inhibited the AA-, collagen- (>100 microg/mL of IPB), and thrombin (>250 microg/mL of IPB)-induced thromboxane B(2) (TXB(2)) production by more than 90%. However, IPB extract showed little effect on thrombin-induced aggregation. These results indicated that aqueous components of IPB are potential ROS scavengers and may prevent the platelet aggregation possibly via scavenging ROS or inhibition of TXB(2) production.

  12. Gas equilibration and pore water sampling experiment in the opalinus clay at the Mont Terri rock laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Vinsot, A. [Agence Nationale pour la Gestion des Dechets Radioactifs (ANDRA), Lab. de recherche souterrain 92 - Chatenay Malabry (France); Fierz, T. [Solexperts, Schwerzenbach (Switzerland); Cailteau, C.; Donato, P. de [Institut National Polytechnique, LEM, UMR 7569 CNRS, ENSG/INPL, 54 - Vandoeuvre-les-Nancy (France); Cailteau, C.; Pironon, J. [G2R-CREGU (UMR 7566 CNRS), 54 - Vandoeuvre-les-Nancy (France); Pepa, S. [Metro Mesures, 91 - Mennecy (France); Wersin, P. [National Cooperative for the Disposal of Radioactive Waste (NAGRA), Wettingen (Switzerland); Canniere, P. de [SCK-CEN, Mol (Belgium); Gubler, H.E. [Bundesanstalt fur Geowissenschaften und Rohstoffe (BGR), Hannover (Germany); Badertscher, N. [Geotechnical Institute, St-Ursanne (Switzerland); Eichinger, L. [Hydroisotop, Schweitenkirchen (Germany)

    2005-07-01

    The study of the mechanisms governing the composition of the interstitial fluids in clay formations with very low permeability constitutes a part of the scientific programmes associated with the feasibility analyses of deep repositories for the geological disposal of long-lived radioactive waste. Several in-situ geochemical experiments have been performed since 1996 in the Mont Terri Rock Laboratory to develop methods for studying these mechanisms in the Opalinus Clay formation. These experiments enabled to build a conceptual model of the interstitial water in the Opalinus Clay. The main uncertainties of this model deal with the carbonate system and the redox state of the water. Consecutively, the PC-C experiment was initiated in 2003 to reduce these uncertainties using: i) a gas equilibration, and, ii) isobar water sampling. (authors)

  13. On the contemporary – and contemporary art history. A review of Terry Smith, What Is Contemporary Art

    Directory of Open Access Journals (Sweden)

    Anthony Gardner

    2011-06-01

    Full Text Available This analysis of Terry Smith’s 'What Is Contemporary Art?' evaluates Smith’s ongoing project to theorise contemporary art around the theme of multiple, interconnected temporalities. It questions how this ‘contemporaneity’ differs from the classic teleologism of modernism and postmodern relativism and suggests that Smith’s categories may be valuable for understanding other cultural areas, such as contemporary music. It then raises methodological problems associated with charting the terrain of contemporary art and how they overlap with economic considerations, arguing that the task implies particular forms of privilege that may threaten the autonomy of critical analysis, but that Smith’s work goes some way toward exposing this problem.

  14. A Statistical Investigation into the Determining Woven Fabric Defects That Occur on Raw Terry Fabrics During Weaving Production

    Directory of Open Access Journals (Sweden)

    Deniz Mutlu Ala

    2014-07-01

    Full Text Available In this study, the number of specific woven fabric defects occured on raw terry fabrics during weaving production were investigated with statistical process control techniques. Raw fabrics of a selected standart fabric production were inspected for defect detection after weaving operation in a towel production company. Defects were detected by inspection of fabric on a lighted control board by experienced experts. Number of defects were noted on quality control charts. Applying pareto analysis, defects were revealed that formed 80% of total defects. Cause-effect diagrams and p control charts were created and solution suggestions to avoid these defects were presented keeping in mind that eliminating elementary causes, which is 20% of total problems, can resolve 80% of resources of problems.

  15. Supervisor's role in training programs as a manager of learning program

    Directory of Open Access Journals (Sweden)

    2011-06-01

    Full Text Available According to the training literature, a supervisor's role in training programs has two major elements: supervisor support and supervisor communication. The ability of supervisors to play effective roles in training programs may increase employees' motivation to learn. The nature of this relationship is interesting, but the role of supervisor's role as a predicting variable is less emphasized in a training program models. Therefore, this study was conducted to examine the effect of supervisor's role in training programs on motivation to learn using 152 usable questionnaires gathered from non-academic employees who have worked in a technological based public university, Malaysia. The outcomes of stepwise regression analysis showed that the supervisor support and supervisor communication significantly associated with motivation to learn. Statistically, this result demonstrates that supervisor's role in training programs does act as an important predictor of motivation to learn in the organizational sample. In addition, discussion, implication and conclusion are elaborated.

  16. Supervisor perspectives on the summative in-training assessment.

    Science.gov (United States)

    Scarff, Catherine E; Bearman, Margaret; Corderoy, Robert M

    2016-05-01

    Assessment is a fundamental component of medical education and exists in many formats. In-training assessments are one such example and they serve to provide feedback to learners about their performance during a period of clinical attachment. However, in addition to trainee knowledge and performance, many factors influence the assessment given to a trainee. This study used an anonymous survey to investigate the perceptions of supervisors of the influences on their assessments of Australian dermatology trainees, focusing on the summative in-training assessment (SITA) format. A response rate of 41% was achieved. The importance of reporting underperformance and providing feedback to trainees was agreed on, but current limitations in the ability of the tool to do this were noted. Implications for practice are discussed including the education and support of supervisors, consideration of logistical issues, the process of SITA completion and supervisor appointment. Further research into the impact of supervisor concerns about potential challenges to a judgement and hesitations about making negative comments about a trainee are required. Examination of the trainee perspective is also required. Quality feedback is essential for learners to guide and improve their performance. Supervisors face many potential influences on their assessments and if these are too great, they may jeopardise the quality of the assessment given. Attention to highlighted areas may serve to improve the process, so allowing trainees to develop into the best clinicians they can be. © 2015 The Australasian College of Dermatologists.

  17. Enhancing nurses' empowerment: the role of supervisors' empowering management practices.

    Science.gov (United States)

    Montani, Francesco; Courcy, François; Giorgi, Gabriele; Boilard, Amélie

    2015-09-01

    This study tests a theoretical model where: (a) nurses' dispositional resistance to change is indirectly negatively related to behavioural empowerment through the mediating role of psychological empowerment; and (b) supervisors' empowering management practices buffer both the negative relationship between dispositional resistance to change and psychological empowerment and the indirect negative relationship between resistance to change and behavioural empowerment via psychological empowerment. Promoting a high level of empowerment among nursing personnel is important to ensure their effectiveness in the context of organizational change. It is thus essential to advance our current understanding of the factors that hamper nurses' psychological and behavioural expressions of empowerment and to clarify supervisor practices that can overcome such barriers. A cross-sectional research design. We collected survey data during 2012 from a sample of 197 nurses from a Canadian hospital undergoing a major organizational change. Results from moderated mediation analyses provided evidence for an indirect negative relationship between dispositional resistance to change and behavioural empowerment through psychological empowerment, and for a moderating (buffering) effect of supervisors' empowering management practices on this mediated relationship. These findings provided support for our hypotheses. Supervisors' empowering management practices represent an important contextual buffer against the negative effects of dispositional resistance to change on nurses' empowerment. Organizations should develop empowering management skills among nurses' supervisors to counteract the detrimental effects of dispositional resistance to change and to sustain an empowered nursing workforce. © 2015 John Wiley & Sons Ltd.

  18. Evaluación de la actividad repelente de aceites esenciales de plantas Piperáceas del departamento de Chocó, Colombia

    OpenAIRE

    2015-01-01

    El objetivo de este trabajo fu e determinar la composición química volátil del aceite esencial de varias especies de Piper áceas ( Piper dilatatum, Piper aduncum, Piper divaricatum, Piper sp, Piper sanctifelicis) y la actividad repelente de ellos contra el gorgojo de granos almacenados Tribolium castaneum Herbst. Los aceites esenciales se obtuvieron por hidrodestilación, la separación e identificación de los component es volátiles se realizó por cromatografía de gase...

  19. The views of teachers about the ethical behaviors of Educational Supervisors and Ministry’s Supervisors

    Directory of Open Access Journals (Sweden)

    Nurhayat Çelebi

    2012-08-01

    Full Text Available Normal 0 21 false false false TR X-NONE X-NONE The aim of this research has to find out primary and high school teachers’ perceptions of supervisors’ ethical behaviour. The model of the research was descriptive survey. The sampling of research was formed by 112 teachers working in Avcılar, Istanbul. 52 of those teachers are working in primary schools and the rest (60 were working in high schools. The measurement tool used in this research was developed by Akyıldız (2007 to measure teachers’ perceptions of ethical behaviour. The scale has 37 items and formed as 5 items Likert type. Internal consistency of the scale was found .95. Factorial sub-dimensions’ item total correlation coefficients were between .75 and .70. The methods used in analysis process are factorial analysis, independent samples t test, two-way ANOVA, independent samples non-parametric Kruskal Wallis H, Mann Whitney-U. According to the results of factorial analysis, teachers’ perceptions of ethhical behaviours were formed within 5 groups. These dimensions are: “professional moral”, “common sense”, “honesty”, “objectivity”, “responsibility”. Teachers’ perceptions were found out meaningfully different considering school type but didn’t different according to gender. Also, each factorial sub-dimension was examined and “objectivity, honesty and discourse ethics” sub-dimensions were found different according to job experience, and honesty according to educational level. According to the results of the research, teachers found ministry’s supervisors more positive than educational supervisors.

  20. Piper and Vismia species from Colombian Amazonia differentially affect cell proliferation of hepatocarcinoma cells.

    Science.gov (United States)

    Lizcano, Leandro J; Siles, Maite; Trepiana, Jenifer; Hernández, M Luisa; Navarro, Rosaura; Ruiz-Larrea, M Begoña; Ruiz-Sanz, José Ignacio

    2014-12-30

    There is an increasing interest to identify plant-derived natural products with antitumor activities. In this work, we have studied the effects of aqueous leaf extracts from Amazonian Vismia and Piper species on human hepatocarcinoma cell toxicity. Results showed that, depending on the cell type, the plants displayed differential effects; thus, Vismia baccifera induced the selective killing of HepG2, while increasing cell growth of PLC-PRF and SK-HEP-1. In contrast, these two last cell lines were sensitive to the toxicity by Piper krukoffii and Piper putumayoense, while the Piperaceae did not affect HepG2 growth. All the extracts induced cytotoxicity to rat hepatoma McA-RH7777, but were innocuous (V. baccifera at concentrations Piper genera with opposite effects as a model system to study the mechanisms of the antitumoral activity against different types of hepatocarcinoma.

  1. Secondary metabolites from the phloem of Piper solmsianum (Piperaceae) in the honeydew of Edessa meditabunda.

    Science.gov (United States)

    Ramos, Clécio S; Kato, Massuo J

    2012-01-01

    The phytochemistry of species of the genus Piper has been studied extensively, including Piper solmsianum. However, no studies have addressed the phytochemistry of the sap content of Piper species. To evaluate the transferring of secondary compounds from the saps of P. solmsianum to the honeydew of Edessa meditabunda. The honeydew of E. meditabunda and saps of P. solmsianum were analysed by GC-MS, (1) H-NMR and LC-MS. The lignan (-)-grandisin and the phenylpropanoid (E)-isoelemicin were detected in both saps of P. solmsianum and honeydew of E. meditabunda. Analysis of honeydew secreted by the sap-sucking insect E. meditabunda indicated that (-)-grandisin and (E)-isoelemicin are absorbed from the phloem of Piper solmsianum. Copyright © 2012 John Wiley & Sons, Ltd.

  2. PRENYLATED BENZOIC ACID DERIVATIVES FROM PIPER SPECIES AS SOURCE OF ANTI-INFECTIVE AGENTS

    OpenAIRE

    2012-01-01

    A number of prenylated benzoic acids derivatives with interesting biological activities have been previously isolated and characterized from different species of piperaceae family. Several Piper species contained structurally similar compounds with diverse biological activities such as anti-bacterial, anti-fungal, insecticidal as well as anti-parasitic all of which produces compounds that can be classified as prenylated benzoic acid derivatives. Piper sp has proven to serve as a source of pot...

  3. Supervisor leadership in relation to resident job satisfaction.

    Science.gov (United States)

    van der Wal, Martha A; Schönrock-Adema, Johanna; Scheele, Fedde; Schripsema, Nienke R; Jaarsma, A Debbie C; Cohen-Schotanus, Janke

    2016-08-01

    Research from outside the medical field shows that leadership behaviours influence job satisfaction. Whether the same is true for the medical training setting needs to be explored. The aim of this study was to investigate the influence of residents' overall appreciation of their supervisor's leadership and observation of specific supervisor leadership behaviours on job satisfaction. We invited residents (N = 117) to rate how often they observed certain task and relation-oriented leadership behaviours in their supervisor and overall appreciation of their supervisor's leadership. Furthermore, they rated their satisfaction with 13 different aspects of their jobs on a 10-point scale. Using exploratory factor analysis we identified four factors covering different types of job satisfaction aspects: personal growth, autonomy, affective, and instrumental job satisfaction aspects. Influence of overall appreciation for supervisor leadership and observation of certain leadership behaviours on these job satisfaction factors were analysed using multiple regression analyses. The affective aspects of job satisfaction were positively influenced by overall appreciation of leadership (B = 0.792, p = 0.017), observation of specific instructions (B = 0.972, p = 0.008) and two-way communication (B = 1.376, p = 0.008) and negatively by mutual decision-making (B = -1.285, p = 0.007). No effects were found for the other three factors of job satisfaction. We recommend that supervisors become more aware of whether and how their behaviours influence residents' job satisfaction. Especially providing specific instructions and using two-way communication seem important to help residents deal with their insecurities and to offer them support.

  4. Biological role of Piper nigrum L. (Black pepper):A review

    Institute of Scientific and Technical Information of China (English)

    Nisar Ahmad; Hina Fazal; Bilal Haider Abbasi; Shahid Farooq; Mohammad Ali; Mubarak Ali Khan

    2012-01-01

    Piper nigrum L. is considered the king of spices throughout the world due to its pungent principle piperine. Peppercorn of Piper nigrum as a whole or its active components are used in most of the food items. Different parts of Piper nigrum including secondary metabolites are also used as drug, preservative, insecticidal and larvicidal control agents. Biologically Piper nigrum is very important specie. The biological role of this specie is explained in different experiments that peppercorn and secondary metabolites of Piper nigrum can be used as Antiapoptotic, Antibacterial, Anti-Colon toxin, Antidepressant, Antifungal, Antidiarrhoeal, Anti-inflammatory, Antimutagenic, Anti-metastatic activity, Antioxidative, Antiriyretic, Antispasmodic, Antispermatogenic, Antitumor, Antithyroid, Ciprofloxacin potentiator, Cold extremities, Gastric ailments, Hepatoprotective, Insecticidal activity, Intermittent fever and Larvisidal activity. Other roles of this specie includes protection against diabetes induced oxidative stress; Piperine protect oxidation of various chemicals, decreased mitochondrial lipid peroxidation, inhibition of aryl hydroxylation, increased bioavailability of vaccine and sparteine, increase the bioavailability of active compounds, delayed elimination of antiepileptic drug, increased orocecal transit time, piperine influenced and activate the biomembrane to absorb variety of active agents, increased serum concentration, reducing mutational events, tumour inhibitory activity, Piperine inhibite mitochondrial oxidative phosphorylation, growth stimulatory activity and chemopreventive effect. This review based on the biological role of Piper nigrum can provide that the peppercorn or other parts can be used as crude drug for various diseases while the secondary metabolites such as piperine can be used for specific diseases.

  5. Investigations on Piper betle grown in Sri Lanka.

    Science.gov (United States)

    Arambewela, L S R; Arawwawala, L D A M; Kumaratunga, K G; Dissanayake, D S; Ratnasooriya, W D; Kumarasingha, S P

    2011-07-01

    Piper betle is an economically important plant cultivated in Sri Lanka. Although more than 12 cultivars of betel are reported in Sri Lanka, very few scientific investigations have been carried out on them. Studies on the chemical constituents indicated that safrole is the major constituent, followed by chavibitol acetate, in the essential oil of common betel leaves of Sri Lanka. Investigations on the bioactivities of P. betle revealed the presence of antimicrobial, insecticidal, antioxidant, antinociceptive, antidiabetic and gastroprotective activities. In addition, P. betle was found to be safe in terms of hepatotoxicity, renotoxicity, hematotoxicity, gross morphology, weights of organs, stress or aversive behaviors in rats. The above findings indicate the vast potential of P. betle yet to be harnessed for the benefit of mankind and the betel industry of Sri Lanka.

  6. [Alkaloids and lignans from stems of Piper betle].

    Science.gov (United States)

    Huang, Xiangzhong; Yin, Yan; Huang, Wenquan; Sun, Kuizong; Cheng, Chunmei; Bai, Lian; Dai, Yun

    2010-09-01

    Alkaloids and lignans from the stems of Piper betle were studied. Compounds were isolated and purified by repeated silica gel, reverse phase silica gel, Sephadex LH-20 column chromatography and preparative thin layer chromatography. The structures were elucidated on the basis of spectral analysis. From the ethyl acetate soluble fractions of the 70% acetone extract, ten compounds were isolated and identified as piperine (1), pellitorine (2), N-isobutyl-2E,4E-dodecadienamide (3), dehydropipernonaline (4), piperdardine (5), piperolein-B (6), guineensine (7), (2E,4E)-N-isobutyl-7-(3',4'-methylenedioxyphenyl)-2,4-heptadienamide (8), syringaresinol-O-beta-D-glucopyranoside (9),pinoresinol (10). All Compounds were isolated from the plant for the first time, and compounds 9 and 10 were isolated firstly from the genus.

  7. A chromene and prenylated benzoic acid from Piper aduncum.

    Science.gov (United States)

    Baldoqui, D C; Kato, M J; Cavalheiro, A J; Bolzani, V da S; Young, M C; Furlan, M

    1999-08-01

    In addition to nerolidol, 2',6'-dihydroxy-4'-methoxydihydrochalcone, methyl 2,2-dimethyl-8-(3'-methyl-2'-butenyl)-2H-1-chromene-6-carboxylate, methyl 2,2-dimethyl-2H-1-chromene-6-carboxylate and methyl 8-hydroxy-2,2-dimethyl-2H-1-chromene-6-carboxylate, two new natural products were isolated from the leaves of Piper aduncum, 2,2-dimethyl-2H-1-chromene-6-carboxylic acid and 3-(3',7'-dimethyl-2',6'-octadienyl)-4-methoxybenzoic acid. The structures of the isolates were established based on analysis of spectroscopic data, including ES-MS. The DNA-damaging activity of the isolated compounds was also investigated against mutant strains of Saccharomyces cerevisiae.

  8. Amides and neolignans from the aerial parts of Piper bonii.

    Science.gov (United States)

    Ding, Duo-Duo; Wang, Yue-Hu; Chen, Ya-Hui; Mei, Ren-Qiang; Yang, Jun; Luo, Ji-Feng; Li, Yan; Long, Chun-Lin; Kong, Yi

    2016-09-01

    Six amides, piperbonamides A-F, three neolignans piperbonins A-C, and 11 known compounds were isolated from the aerial parts of Piper bonii (Piperaceae). The structures of piperbonamides A-F and piperbonins A-C were elucidated based on the analysis of 1D and 2D NMR and MS data. Piperbonin A, (+)-trans-acuminatin, (+)-cis-acuminatin, (+)-kadsurenone, and pipernonaline showed weak activity against platelet aggregation with IC50 values of 118.2, 108.5, 90.02, 107.3, and 116.3 μM, respectively, as compared with the positive control, tirofiban, with an IC50 value of 5.24 μM. Piperbonamides A-F were inactive against five tumor cell lines at concentrations up to 40 μM. Copyright © 2016. Published by Elsevier Ltd.

  9. Estudio químico de piper steerni1

    Directory of Open Access Journals (Sweden)

    Rafael Posso O.

    2010-07-01

    Full Text Available Del extracto clorofórmico de las hojas de Piper steerni se aislaron por métodos cromatográficos 5,7-dihidroxyflavanona, 5-hidroxi-7-metoxinavona y P-sitosterol; cl extracto en acetato de etilo del tallo del mismo vegetal presentó iguales constituyentes que las hojas junto con bases nitrogenadas de las cuales se identificó N-(4-hidroxifcniletilen cinamamida como un nuevo compuesto en la familia Piperaceae. Los metabolitos secundarios mayoritarios del aceite esencial de las hojas de P. steerni fueron caracterizados como benzaldehido, alcohol bencílico y benzoato de etilo. Las estructuras de los compuestos fueron establecidas por métodos quimicos y espectroscópicos y por correlaciones con substancias conocidas.

  10. Antifungal piperolides from Piper malacophyllum (Prels) C. DC

    Energy Technology Data Exchange (ETDEWEB)

    Lago, Joao Henrique G. [Universidade Presbiteriana Mackenzie, Sao Paulo, SP (Brazil). Faculdade de Ciencias Biologicas, Exatas e Experimentais; Tanizaki, Tatiane M.; Kato, Massuo J. [Sao Paulo Univ., SP (Brazil). Inst. de Quimica]. E-mail: majokato@iq.usp.br; Young, Maria Claudia M. [Instituto de Botanica, Sao Paulo, SP (Brazil). Secao de Fisiologia e Bioquimica de Plantas; Guimaraes, Elsie F. [Instituto de Pesquisas Jardim Botanico do Rio de Janeiro, RJ (Brazil)

    2005-04-01

    Bioactivity-guided fractionation of the CH{sub 2}Cl{sub 2} extract from leaves of Piper malacophyllum using bioautography assay against fungi, led to the isolation of two known bioactive piperolides: 4,6-dimethoxy-5-E-phenyl butenolide (1) and 4,6-dimethoxy-5-Z-phenyl butenolide (2). IR, MS and NMR spectroscopic data were used for the identification of these compounds including comparison with previously reported data. The E configuration is associated to higher activity for compound 1, since the minimum amount required for the growth inhibition of Cladosporium cladosporioides and C. sphaerospermum were 1.0/1.0 {mu}g (1) and 5.0/10.0 {mu}g (2), respectively. (author)

  11. Antifungal Constituents from the Roots of Piper dilatatum Rich.

    Directory of Open Access Journals (Sweden)

    Ruilan Alves dos Santos

    2013-01-01

    Full Text Available The compounds (+-(7S,8R-epoxy-5,6-didehydrokavain (1, flavokavain B (2, β-sitosterol (3, and stigmasterol (4 are reported here as chemical constituents of Piper dilatatum Rich. (Piperaceae. Their structures were determined on the basis of their spectroscopic data (1H and 13C NMR, MS, and IR. The antifungal activities of pyrone 1 (1 μg and chalcone 2 (100 μg were determined by means of direct bioautography against Cladosporium cladosporioides and C. sphaerospermum. Results indicate P. dilatatum as a candidate for the development of novel antifungal phytotherapic products as well as point out pyrone 1 as a promising hit compound in the quest for novel antifungal agents.

  12. Anticholinesterases and antioxidant alkamides from Piper nigrum fruits.

    Science.gov (United States)

    Tu, Yanbei; Zhong, Yujiao; Du, Hongjian; Luo, Wei; Wen, Yaya; Li, Qin; Zhu, Chao; Li, Yanfang

    2016-09-01

    The anticholinesterase and antioxidant effects of five different extracts of Piper nigrum were evaluated. Twenty-one known alkamides were isolated from active ethyl acetate extract and investigated for their cholinesterase inhibitory and antioxidant effects. Among them, piperine (2), piperettine (5) and piperettyline (20) exhibited dual inhibition against AChE and BChE, and feruperine (18) was the most potent selective inhibitor of BChE. Molecular docking simulation was performed to get insight into the binding interactions of the ligands and enzymes. In addition, N-trans-feruloyltyramine (3) contributed to the strongest DPPH radical-scavenging activity. The self-induced Aβ aggregation inhibition of 2, 5 and 18 was further evaluated. Results indicated that some alkamides could be multifunctional lead candidates for Alzheimer's disease therapy.

  13. Investigations on Piper betle grown in Sri Lanka

    Directory of Open Access Journals (Sweden)

    L.S.R Arambewela

    2011-01-01

    Full Text Available Piper betle is an economically important plant cultivated in Sri Lanka. Although more than 12 cultivars of betel are reported in Sri Lanka, very few scientific investigations have been carried out on them. Studies on the chemical constituents indicated that safrole is the major constituent, followed by chavibitol acetate, in the essential oil of common betel leaves of Sri Lanka. Investigations on the bioactivities of P. betle revealed the presence of antimicrobial, insecticidal, antioxidant, antinociceptive, antidiabetic and gastroprotective activities. In addition, P. betle was found to be safe in terms of hepatotoxicity, renotoxicity, hematotoxicity, gross morphology, weights of organs, stress or aversive behaviors in rats. The above findings indicate the vast potential of P. betle yet to be harnessed for the benefit of mankind and the betel industry of Sri Lanka.

  14. A patient safety curriculum for medical residents based on the perspectives of residents and supervisors.

    NARCIS (Netherlands)

    Jansma, J.D.; Wagner, C.; Bijnen, A.B.

    2011-01-01

    Objectives: To develop a patient safety course for medical residents based on the views of medical residents and their supervisors. Methods: In 2007, questionnaires were distributed to investigate residents' and supervisors' perspectives on the current patient safety performance and educational

  15. Implementation of the participatory approach for supervisors to prevent sick leave : a process evaluation

    NARCIS (Netherlands)

    Kraaijeveld, R. A.; Schaafsma, F. G.; Ketelaar, S.M.; Boot, C. R. L.; Bultmann, U.; Anema, J. R.

    2016-01-01

    To perform a process evaluation of a multifaceted strategy to implement the participatory approach for supervisors to prevent sick leave in three organisations. The implementation strategy incorporated a working group meeting with stakeholder representatives, supervisor training, and optional superv

  16. Supervisors' and residents' patient-education competency in challenging outpatient consultations

    NARCIS (Netherlands)

    Wouda, Jan C.; van de Wiel, Harry B. M.

    2015-01-01

    Objectives: We compared supervisors' and residents' patient-education competency in challenging consultations in order to establish whether supervisors demonstrate sufficient patient-education competency to act credibly as role models and coaches for residents. Methods: All consultations conducted a

  17. The Relation Between Supervisors' Big Five Personality Traits and Employees' Experiences of Abusive Supervision.

    Science.gov (United States)

    Camps, Jeroen; Stouten, Jeroen; Euwema, Martin

    2016-01-01

    The present study investigates the relation between supervisors' personality traits and employees' experiences of supervisory abuse, an area that - to date - remained largely unexplored in previous research. Field data collected from 103 supervisor-subordinate dyads showed that contrary to our expectations supervisors' agreeableness and neuroticism were not significantly related to abusive supervision, nor were supervisors' extraversion or openness to experience. Interestingly, however, our findings revealed a positive relation between supervisors' conscientiousness and abusive supervision. That is, supervisors high in conscientiousness were more likely to be perceived as an abusive supervisor by their employees. Overall, our findings do suggest that supervisors' Big Five personality traits explain only a limited amount of the variability in employees' experiences of abusive supervision.

  18. SUPERVISORS' TRANSFORMATIONAL LEADERSHIP AND BULLYING IN THE WORKPLACE.

    Science.gov (United States)

    Dussault, Marc; Frenette, Éric

    2015-12-01

    The study tests the relationship between supervisors' transformational, transactional, and laissez-faire leadership and perceived bullying in the workplace. Transformational and transactional leaders can create conditions that make bullying at work less frequent but laissez-faire leadership may cause conflict that can result in bullying. The participants were 288 adults (122 women, 164 men; M age = 38.9 yr., SD = 11.7; M tenure = 7.2 yr.) employed across several organizations. Of the participants, 53.2% were contacted during an evening class in organizational behavior, and the others were workers from a waterproofing company. Scales measuring perceived leadership of a supervisor and perceived bullying at work were administered. Supervisor's transformational and transactional leadership were negatively related to work-related bullying, person-related bullying, and physically intimidating bullying. Transactional leadership was also negatively related to Work-related bullying, perceived Person-related bullying, and perceived Physically intimidating bullying. Supervisor's laissez-faire leadership was positively related to Work-related bullying, perceived Person-related bullying, and perceived Physically intimidating bullying. The use of Bass's model of transformational leadership in relation with the three-factor structure of the Negative Acts Questionnaire-Revised is unique in research on leadership and bullying. The relationship between laissez-faire leadership and leadership support results from previous studies: transactional or transformational leadership is likely to provide an environment that makes bullying more rare than under a negative or passive leadership.

  19. Trends in Industry Supervisors' Feedback on Business Communication Internships

    Science.gov (United States)

    Sapp, David Alan; Zhang, Qin

    2009-01-01

    The purpose of this empirical study is to explore expectations of industry insiders and identify how student interns are performing in relation to those expectations as defined by 11 performance areas. The results of a survey of 238 industry supervisors were collected over a 5-year period in the departments of English and communication at a…

  20. TESL Degree Candidates' Perceptions of Trust in Supervisors.

    Science.gov (United States)

    Chamberlin, Carla R.

    2000-01-01

    Reports on a study of how nonverbal cues during supervision affect Teaching English as a Second Language (TESL) graduate students' impressions of the trustworthiness of supervisors. Particular features of nonverbal communication during supervision were staged in video materials constructed specifically for the research. Students evaluated the…

  1. EAP Referrals: From Supervisor Training to Client Assessment.

    Science.gov (United States)

    Schneider, Rob; Colan, Neil

    For several decades Employee Assistance Programs (EAPs) have been a resource in the workplace to handle troubled employees. The areas of supervisor training and employee motivation provide opportunities for involvement of psychologists in the EAP field. Surveys conducted with EAP directors revealed that many programs are planning to do supervisor…

  2. Skills and Attributes of Instructional Supervisors: Experience from Kenya

    Science.gov (United States)

    Zachariah, Wanzare O.

    2013-01-01

    In recent years, instructional supervision has been given a great deal of attention in teacher education professional literature. However, few reported studies have specifically focused on desired qualities of instructional supervisors, especially in Third World countries. This paper reports the perceptions of teachers, headteachers and senior…

  3. Trends in Industry Supervisors' Feedback on Business Communication Internships

    Science.gov (United States)

    Sapp, David Alan; Zhang, Qin

    2009-01-01

    The purpose of this empirical study is to explore expectations of industry insiders and identify how student interns are performing in relation to those expectations as defined by 11 performance areas. The results of a survey of 238 industry supervisors were collected over a 5-year period in the departments of English and communication at a…

  4. 42 CFR 493.1449 - Standard; Technical supervisor qualifications.

    Science.gov (United States)

    2010-10-01

    ... Testing Laboratories Performing High Complexity Testing § 493.1449 Standard; Technical supervisor qualifications. The laboratory must employ one or more individuals who are qualified by education and either... service in which the laboratory performs high complexity tests or procedures. The director of a laboratory...

  5. Food Service Supervisor. Dietetic Support Personnel Achievement Test.

    Science.gov (United States)

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater.

    This guide contains a series of multiple-choice items and guidelines to assist instructors in composing criterion-referenced tests for use in the food service supervisor component of Oklahoma's Dietetic Support Personnel training program. Test items addressing each of the following occupational duty areas are provided: human relations; nutrient…

  6. Style and Quality in Research Supervision: The Supervisor Dependency Factor.

    Science.gov (United States)

    Kam, Booi Hon

    1997-01-01

    A survey of 250 graduate research students examined the extent of dependency on supervisors in a range of research-related tasks, and how that dependency affected the research supervision process. Results suggest appropriate research supervision has no set prescription, but interactions among quality and style of supervision, role expectations of…

  7. Teachers' Loyalty to Their Supervisors and Organizational Commitment

    Science.gov (United States)

    Çelebi, Nurhayat; Korumaz, Mithat

    2016-01-01

    A number of studies on teachers' organizational commitment based some findings of western context in Turkey. But some of the characteristics prove that organizational issues cannot be resulted with the terms in Western World. One of the new concepts in organizational issues for Eastern culture is loyalty to supervisor (in school context supervisor…

  8. Business Education University Supervisors' Perspectives of Mentor Teachers' Competencies

    Science.gov (United States)

    Fletcher, Edward C., Jr.

    2012-01-01

    This study examined the perspectives of an expert panel of 31 business education university supervisors from the U.S. and Canada using a modified Delphi approach regarding the areas in which mentor teachers are typically most and least prepared. Findings indicated business education mentor teachers are most prepared in the areas of classroom…

  9. Exploring Supervisor and Supervisee Experiences of Triadic Supervision

    Science.gov (United States)

    Derrick, Emily C.

    2010-01-01

    This dissertation research focused on supervisor and supervisee experiences within the triadic supervision triad. Triadic supervision is an emerging method of supervision within counselor education. It is fast becoming the preferred mode of supervision in counselor education programs. Unfortunately, there is very little research to support the…

  10. Cognitions of Expert Supervisors in Academe: A Concept Mapping Approach

    Science.gov (United States)

    Kemer, Gülsah; Borders, L. DiAnne; Willse, John

    2014-01-01

    Eighteen expert supervisors reported their thoughts while preparing for, conducting, and evaluating their supervision sessions. Concept mapping (Kane & Trochim, [Kane, M., 2007]) yielded 195 cognitions classified into 25 cognitive categories organized into 5 supervision areas: conceptualization of supervision, supervisee assessment,…

  11. A Supervisor's Roles for Successful Thesis and Dissertation

    Science.gov (United States)

    Mhunpiew, Nathara

    2013-01-01

    The success of a thesis or a dissertation for a graduate student relies upon the roles of their supervisor. The student not only needs to be equipped with the knowledge, but also be able to manage others and external factors at the same time. The journey during the period of conducting research is mixed with various tasks. Five supportive roles of…

  12. Adaptive Research Supervision: Exploring Expert Thesis Supervisors' Practical Knowledge

    Science.gov (United States)

    de Kleijn, Renske A. M.; Meijer, Paulien C.; Brekelmans, Mieke; Pilot, Albert

    2015-01-01

    Several researchers have suggested the importance of being responsive to students' needs in research supervision. Adapting support strategies to students' needs in light of the goals of a task is referred to as "adaptivity." In the present study, the practice of adaptivity is explored by interviewing expert thesis supervisors about…

  13. Leadership Effectiveness : A Supervisor's Approach to Manage Return to Work

    NARCIS (Netherlands)

    Schreuder, J. A. H.; Groothoff, J. W.; Jongsma, D.; van Zweeden, N. F.; van der Klink, J. J. L.; Roelen, C. A. M.

    2013-01-01

    Purpose To investigate adaptive leadership in relation to personnel sickness absence (SA). In situational leadership, supervisors are effective if they adapt their leadership style appropriately to a given situation. Methods A managerial reorganization in a Dutch hospital with reassignment of superv

  14. Female Supervisors of Arab School Education in Israel

    Science.gov (United States)

    Arar, Khalid Husny

    2014-01-01

    This paper discusses the characteristics of women discipline supervisors in the Arab education system in Israel, through their professional development to their attainment of senior supervisory posts. It examines how they attain supervision posts and perform various managerial functions in what is considered a male role, in a patriarchal society,…

  15. Exploring differential effects of supervisor support on transfer of training

    NARCIS (Netherlands)

    Nijman, D.J.J.M.; Nijhof, W.J.; Wognum, A.A.M.; Veldkamp, B.P.

    2006-01-01

    Purpose – The purpose of this article is to provide further insight into the relationship between supervisor support and transfer of training, by taking into account the effects of other transfer‐influencing factors in a systemic approach of the transfer process. Design/methodology/approach – A rev

  16. Educational Supervisors' Metaphorical Roots of Beliefs about Teaching and Learning

    Science.gov (United States)

    Buaraphan, Khajornsak

    2012-01-01

    Beliefs are a complex psychological construct that have potential to drive a person to make decisions and act. A person's metaphors can serve as roots of their beliefs. In this study, the metaphor construction task (MCT) was utilized to uncover beliefs about teaching and learning held by 216 educational supervisors from 10 provinces in the central…

  17. The Supervisor and On-the-Job Training. Fourth Edition.

    Science.gov (United States)

    Broadwell, Martin M.

    This training book is designed to help supervisors give accurate and effective on-the-job training (OJT) to employees under their supervision. Chapter 1 identifies good and bad training and good and bad reasons for training. Chapter 2 examines human learning and three motivators: desire for reward, fear of punishment, and curiosity. Chapter 3…

  18. Evaluación de la actividad repelente de aceites esenciales de plantas Piperáceas del departamento de Chocó, Colombia

    Directory of Open Access Journals (Sweden)

    BE Jaramillo-Colorado

    2015-01-01

    Full Text Available El objetivo de este trabajo fu e determinar la composición química volátil del aceite esencial de varias especies de Piper áceas ( Piper dilatatum, Piper aduncum, Piper divaricatum, Piper sp, Piper sanctifelicis y la actividad repelente de ellos contra el gorgojo de granos almacenados Tribolium castaneum Herbst. Los aceites esenciales se obtuvieron por hidrodestilación, la separación e identificación de los component es volátiles se realizó por cromatografía de gases acoplada a espectrometría de masas y par a la evaluación de la activ idad repelente se empleó el método de áre a de preferencia. Los compuestos m ayoritarios encontrados en Piper dilatatum fueron el apiol 89,0% y trans -cariofileno (3,5%; en Piper divaricatum, eugenol (37,5% y metil eugenol (36,3%; Piper sp,  - gurjuneno (o guaieno (24,9% y elemol (14,2%; Piper sanctifelicis,  -3-careno (35,3% y limoneno (27,1%; Piper aduncum , dilapiol (48,2% y 1,8 cineol (11,4%. Los porcentajes de repelencia de los aceites esenciales a una concentración de 1 μ L/cm 2 , a un tiempo de exposición de 2 horas frente al T. castaneum fueron: Piper aduncum (99%, Piper sp (96%, Piper dilatatum (82%, Piper divaricatum (76%, Piper santifelicis (33%.

  19. Consistency of Supervisor and Peer Ratings of Assessment Interviews Conducted by Psychology Trainees

    Science.gov (United States)

    Gonsalvez, Craig J.; Deane, Frank P.; Caputi, Peter

    2016-01-01

    Observation of counsellor skills through a one-way mirror, video or audio recording followed by supervisors and peers feedback is common in counsellor training. The nature and extent of agreement between supervisor-peer dyads are unclear. Using a standard scale, supervisors and peers rated 32 interviews by psychology trainees observed through a…

  20. Nonverbal Behaviors and Initial Impressions of Trustworthiness in Teacher-Supervisor Relationships.

    Science.gov (United States)

    Chamberlin, Carla R.

    2000-01-01

    Investigates the relationship between nonverbal behaviors of immediacy and dominance on teachers' initial impressions of trust toward a supervisor. Notes that supervisor immediacy resulted in higher perceptions of trust than supervisor dominance, and immediacy also rated higher on measures of appropriateness and effectiveness than dominance.…

  1. Teacher Supervision Practices and Characteristics of In-School Supervisors in Uganda

    Science.gov (United States)

    Kalule, Lawrence; Bouchamma, Yamina

    2014-01-01

    We examined teacher supervision practices (supervision models, phases, and professional development guidelines) of in-school supervisors (principals, vice principals, and study program directors) in Uganda, the supervisors' efficacy perceptions regarding teacher supervision, and supervisor characteristics associated with the choice of supervisory…

  2. 30 CFR 250.175 - When may the Regional Supervisor grant an SOO?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may the Regional Supervisor grant an SOO... When may the Regional Supervisor grant an SOO? (a) The Regional Supervisor may grant an SOO when... your control, such as unexpected weather, unavoidable accidents, or drilling rig delays. (b) The...

  3. 30 CFR 250.173 - When may the Regional Supervisor direct an SOO or SOP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may the Regional Supervisor direct an SOO or SOP? 250.173 Section 250.173 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... § 250.173 When may the Regional Supervisor direct an SOO or SOP? The Regional Supervisor may direct...

  4. 42 CFR 493.1467 - Condition: Laboratories performing high complexity testing; cytology general supervisor.

    Science.gov (United States)

    2010-10-01

    ... testing; cytology general supervisor. 493.1467 Section 493.1467 Public Health CENTERS FOR MEDICARE....1467 Condition: Laboratories performing high complexity testing; cytology general supervisor. For the subspecialty of cytology, the laboratory must have a general supervisor who meets the qualification...

  5. Morphological and phytochemical characterization of Piper hispidinervum DC. and Piper aduncum L. populations in the state of Acre

    Directory of Open Access Journals (Sweden)

    Jacson Rondinelli da Silva Negreiros

    2015-02-01

    Full Text Available Because of the increasing demand of the industry for the production of essential oils, studies highlight the genetic variability of Piper hispidinervum and P. aduncum species according to their patterns of spatial distribution, showing the Amazon region as the source of superior genetic material in the production of safrole and dillapiole. Thus, the objective this study was to characterize the morphology and the phytochemistry of Piper hispidinervum and P. aduncum populations in the Active Germplasm Bank of Embrapa Acre to generate subsidies for the genetic improvement of these species. The results showed that the average values for leaf width and length were 141.67 and 48.04 mm, and petioles length and diameter measurements were 2.83 and 1.78 mm for P. hispidinervum and 189.22; 67.74; 6.03 and 2.22 mm for P. aduncum respectively. The average height and canopy volume measurements were 2.39 m and 6.30 m3 and 2.70 m and 7.78 m3 respectively for each species. For P. hispidinervum, the population with higher performance indried yield and content of safrole was population 02, with 3.9%, and the population 04 showed 94.3% safrole content, both with genetic material from the region of Acrelândia and Plácido de Castro. To P. aduncum, the populations with better performance were 207, 208 and 209, forming a homogeneous group with dried yield average of 3.8% and dillapiol content of 84-85%. Such populations are indicated for selection in breeding program of these species due to better performance.

  6. 75 FR 43397 - Airworthiness Directives; Piper Aircraft, Inc. Models PA-32R-301T and PA-46-350P Airplanes

    Science.gov (United States)

    2010-07-26

    ...-067-AD; Amendment 39-16338; AD 2010-13-07] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... in the Federal Register on June 23, 2010 (75 FR 35619), and applies to certain Piper Aircraft, Inc... certain Piper Aircraft, Inc. Models PA-32R-301T and PA-46-350P airplanes. AD 2010-13-07 requires you...

  7. 75 FR 7407 - Airworthiness Directives; Piper Aircraft, Inc. Models PA-32R-301T and PA-46-350P Airplanes

    Science.gov (United States)

    2010-02-19

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Piper Aircraft, Inc... airworthiness directive (AD) for certain Piper Aircraft, Inc. Models PA-32R-301T and PA-46-350P airplanes. This... installed on certain Piper Aircraft, Inc. Models PA-32R-301T and PA-46-350P airplanes are failing. The...

  8. Antioxidant and anti-atherogenic activities of three Piper species on atherogenic diet fed hamsters.

    Science.gov (United States)

    Agbor, Gabriel A; Vinson, Joe A; Sortino, Julianne; Johnson, Robert

    2012-05-01

    Atherogenic diet is known to induce high plasma lipid concentration, oxidative stress and early atherosclerosis. Antioxidants have potentials to counter the effect of atherogenic diet. The present research aims at evaluating the antioxidant and anti-atherosclerotic activities of three Piper species (Piper guineense, Piper nigrum and Piper umbellatum) on atherogenic diet fed hamsters. Hamsters divided into 8 groups: normal control, atherosclerotic control and six test groups. The normal animals fed normal rodent chow, the atherosclerotic control animals fed the same rodent chow supplemented with 0.2% cholesterol and 10% coconut oil (high cholesterol diet). The 6 test groups' animals fed same diet as the atherosclerotic control group but with additional supplementation of 2 graded doses (1 and 0.25 mg/kg body weight, o.p.) of plant extracts for 12 weeks. The atherogenic diet induced a collapse of the erythrocyte antioxidant defense system (significant decrease in superoxide dismutase, catalase and glutathione peroxidase activities). Atherogenic diet also induced an increase in plasma total cholesterol, triglyceride, thiobarbituric acid reactive substances (TBARS), oxidation of low density lipoprotein cholesterol (LDL) and accumulation of foam cells in the aorta a hall mark for atherosclerosis. Administration of the Piper species prevented the collapse of the antioxidant system and the increase of plasma parameters maintaining them towards normality. The Piper species also prevented LDL oxidation by increasing the time (lag time) for its oxidation. The results suggest that these Piper species have significant antioxidant and anti-atherogenic effect against atherogenic diet intoxication. Copyright © 2010 Elsevier GmbH. All rights reserved.

  9. Studies of the relationship between employee`s safety consciousness, morale, and supervisor`s leadership in nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Misumi, Jyuji; Hiraki, Tadao; Sakurai, Yukihiro [Institute of Nuclear Safety System Inc., Kyoto (Japan); Yoshida, Michio; Misumi, Emiko; Tokudome, Eiji

    1996-09-01

    This study examined the relationship between employee`s safety consciousness, morale, and supervisor`s leadership using multiple regression analysis. Respondents were 2152 male employees who were working at nuclear power plants (operation division, maintenance division, and joint companies). Main results were as follows. (1) Individual morale variables, such as `work motivation` and `mental hygine`, were correlated with leadership M behavior rather than with P behavior. On the other hand, group morale variables, such as `teamwork` and `meeting quality`, were correlated with both P and M behavior. These results shows P and M leadership affect the employee`s morale. (2) With regard to safety consciousness variables, `communication` and `work place norm` to ensure safety were strongly correlated to leadership both P and M behavior. However, neither `sense of tension to ensure safety` nor `experiencing cold shiver` were related to leadership P or M behavior. It was suggested that practices for accidents prevention in workplace are related to supervisor`s P and M leadership behavior. (3) `Sense of tension` to ensure safety and `experiencing cold shiver` were negatively correlated with `mental hygine`, but positively correlated with `work motivation`. These results suggest that increase of the work motivation might improve employee`s awareness and ability for detecting human errors. (author)

  10. The Supervisor as a Catalyst for Change: A Comparative Study on the Role of the Foreign Language and Science Supervisors.

    Science.gov (United States)

    Papalia, Anthony; Doran, Rodney L.

    This survey was designed to determine the academic background, extra salary, released time, duties, and responsibilities of the foreign language and science supervisors employed by the public secondary schools in Western New York and to identify the role they play in the improvement of instruction. More than 70 completed questionnaires serve as…

  11. Exploring Supervisor-Related Job Resources as Mediators between Supervisor Conflict and Job Attitudes in Hospital Employees.

    Science.gov (United States)

    Elfering, Achim; Gerhardt, Christin; Grebner, Simone; Müller, Urs

    2017-03-01

    Conservation of resources theory assumes loss of resources as a cause of job strain. In hospital work, conflicts with supervisors are tested to predict lower resources, that is, supervisory social support, participation possibilities, and appreciation. All three resources are expected to predict, in turn, experienced stress (job strain) and lower job satisfaction, lower affective commitment, and a higher resigned attitude towards the job (job attitudes). The sample included 1,073 employees from 14 Swiss hospitals (n = 604 nurses, n = 81 physicians, n = 135 medical therapists, and n = 253 technical and administrative staff). Of the total sample, 83.1% were female and 38.9% worked full-time. The median tenure was between 7 years and 10 years. Constructs were assessed by online questionnaires. Structural equation modeling was used to test mediation. Structural equation modeling confirmed the negative association of conflict with supervisors and job resources. Tests of indirect paths to resources as a link between conflicts with supervisors and job attitudes were significant. For nurses, social support, participation and appreciation showed a significant indirect path, while among medical technicians the indirect paths included social support and appreciation, and among physicians only appreciation showed a significant indirect path. In medical therapists no indirect path was significant. Job resources did not mediate the link between conflict with supervisors and stress in any occupational group. Conflicts with supervisors are likely to reduce job resources and in turn to lower job attitudes. Work design in hospitals should, therefore, address interpersonal working conditions and conflict management in leadership development.

  12. Water Retention Capacity of Argillite from the VE Test - Phase II at Mont Terri: Effect of Ventilation

    Energy Technology Data Exchange (ETDEWEB)

    Villar, M. V.; Fernandez, A. M.; Melon, A. M.

    2009-10-12

    The VE (ventilation) test carried out at the Mont Terri underground laboratory in Switzerland intended to evaluate in situ the behaviour of a consolidated clay formation when subjected to alternate periods of flow of wet and dry air during several months. For that, a 10-m gallery was excavated in the Opalinus Clay formation and carefully instrumented. Before and after a second ventilation phase boreholes were drilled. Samples were taken from the drill cores and were analysed from mineralogical and geochemical points of view. Also, the retention curves of these samples were determined in the laboratory following drying paths performed under free volume conditions at 20 degree centigrade, what is the content of this report. Although there are not large differences in the WRC of samples taken from different boreholes, at different distances from the gallery wall or before or after ventilation, those samples taken near the gallery wall and after ventilation tend to show a higher water retention capacity. This has been correlated to the higher salinity of the pore water of these samples, what increases their osmotic suction. This effect is attenuated towards high suctions. (Author) 10 refs.

  13. Emmanuel Levinas and the face of Terri Schiavo: bioethical and phenomenological reflections on a private tragedy and public spectacle.

    Science.gov (United States)

    Dahnke, Michael D

    2012-12-01

    The controversial case of Terri Schiavo came to a close on March 31, 2005, with her death following the removal of a percutaneous endoscopic gastrostomy tube. This event followed years of controversy and social upheaval. Voices from across the entire political and cultural spectrums filled the airwaves and op-ed pages of major newspapers. Protests ensued outside of Ms. Schiavo's care facility. Ms. Schiavo's parents published videos of their daughter on the internet in an effort to prove that she was not in a vegetative state and could potentially recover. There is a certain mystery to the entire controversy given the fact that, legally, it was largely a matter of settled law. Precedent cases and legal statutes clearly set out the proper procedures and decisions to be followed in this case. Nonetheless, powerful challenges and virulent opposition to these standards arose. Through an investigation of this case as well as a comparative study of the case of Dax Cowart (in particular, the documentary depictions of Dax Cowart's case) and of a photograph by Joel-Peter Witkin, I plan to investigate the source of these social upheavals and hypothesize that they were largely the result of a phenomenological reaction to the human face.

  14. Piper sarmentosum enhances fracture healing in ovariectomized osteoporotic rats: a radiological study.

    Science.gov (United States)

    Estai, Mohamed Abdalla; Suhaimi, Farihah Haji; Das, Srijit; Fadzilah, Fazalina Mohd; Alhabshi, Sharifah Majedah Idrus; Shuid, Ahmad Nazrun; Soelaiman, Ima-Nirwana

    2011-01-01

    Osteoporotic fractures are common during osteoporotic states. Piper sarmentosum extract is known to possess antioxidant and anti-inflammatory properties. To observe the radiological changes in fracture calluses following administration of a Piper sarmentosum extract during an estrogen-deficient state. A total of 24 female Sprague-Dawley rats (200-250 g) were randomly divided into 4 groups: (i) the sham-operated group; (ii) the ovariectomized-control group; (iii) the ovariectomized + estrogen-replacement therapy (ovariectomized-control + estrogen replacement therapy) group, which was supplemented with estrogen (100 μg/kg/day); and (iv) the ovariectomized + Piper sarmentosum (ovariectomized + Piper sarmentosum) group, which was supplemented with a water-based Piper sarmentosum extract (125 mg/kg). Six weeks after an ovariectomy, the right femora were fractured at the mid-diaphysis, and a K-wire was inserted. Each group of rats received their respective treatment for 6 weeks. Following sacrifice, the right femora were subjected to radiological assessment. The mean axial callus volume was significantly higher in the ovariectomized-control group (68.2 ± 11.74 mm³) than in the sham-operated, estrogen-replacement-therapy and Piper sarmentosum groups (20.4 ± 4.05, 22.4 ± 4.14 and 17.5 ± 3.68 mm³, respectively). The median callus scores for the sham-operated, estrogen-replacement-therapy and Piper sarmentosum groups had median (range, minimum - maximum value) as 1.0 (0 - 2), 1.0 (1 - 2) and 1.0 (1 - 2), respectively, which were significantly lower than the ovariectomized-control group score of 2.0 (2 - 3). The median fracture scores for the sham-operated, estrogen-replacement-therapy and Piper sarmentosum groups were 3.0 (3 - 4), 3.0 (2 - 3) and 3.0 (2 - 3), respectively, which were significantly higher than the ovariectomized-control group score of 2.0 (1 - 2) (pPiper sarmentosum extract improved fracture healing, as assessed by the reduced callus volumes and

  15. Antioxidant, anticancer, and apoptosis-inducing effects of Piper extracts in HeLa cells

    Directory of Open Access Journals (Sweden)

    Wahyu Widowati

    2013-06-01

    Full Text Available Objective: Cervical cancer is the second most common cancer as well as one of leading cause of cancer-related death for women worldwide. In regards to that issue, focus of this paper will be on popularly used Piperaceae members including Piper betle L, Piper cf fragile Benth, Piper umbellatum L, Piper aduncum L, Piper pellucidum L. This research was conducted to elucidate the antioxidant, anticancer and apoptosis inducing activities of Piperaceae extracts on cervical cancer cells, namely HeLa cell line. Methods: The anticancer activity was determined by inhibiting the proliferation of cells. Apoptosis inducing was determined by inhibiting proliferation cells and by SubG1 flow cytometry. The antioxidant activity is determined by using superoxide dismutase value and 2,2-diphenyl-1-picrylhydrazyl (DPPH radical scavenging activity. Results: The highest anticancer activity at 24 h incubation was found for P.pellucidum extract (IC50: 2.85 µg/ml; The anticancer activity at 48 h incubation was more than at 24 h for all extracts. The highest apoptotic activity was found for P.betle (12.5 µg/ml at both 24 and 48 h incubatio. The highest antioxidant activity was also represented by P.betle extract. Conclusions: All Piperaceae extracts have high anticancer activity; longer incubation increase anticancer activity. P.betle extract has the highest antioxidant property. [J Exp Integr Med 2013; 3(3.000: 225-230

  16. A Late Cretaceous Piper (Piperaceae) from Colombia and diversification patterns for the genus.

    Science.gov (United States)

    Martínez, Camila; Carvalho, Mónica R; Madriñán, Santiago; Jaramillo, Carlos A

    2015-02-01

    Documented fossil floras in the neotropics are sparse, yet their records provide evidence on the spatial and temporal occurrence of taxa, allowing for testing of biogeographical and diversification scenarios on individual lineages. A new fossil Piper from the Late Cretaceous of Colombia is described here, and its importance for assessing diversification patterns in the genus is addressed. Leaf architecture of 32 fossil leaf compressions from the Guaduas Formation was compared with that of 294 extant angiosperm species. The phylogenetic position of the fossil named Piper margaritae sp. nov. was established based on leaf traits and a molecular scaffold of Piper. The age of the fossil was independently used as a calibration point for divergence time estimations. Natural affinities of P. margaritae to the Schilleria clade of Piper indicate that the genus occurred in tropical America by the Late Cretaceous. Estimates of age divergence and lineage accumulation reveal that most of the extant diversity of the genus accrued during the last ∼30 Myr. The recent radiation of Piper is coeval with both the Andean uplift and the emergence of Central America, which have been proposed as important drivers of diversity. This pattern could exemplify a recurrent theme among many neotropical plant lineages. © 2015 Botanical Society of America, Inc.

  17. Piper species protect cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters.

    Science.gov (United States)

    Agbor, Gabriel A; Akinfiresoye, Luli; Sortino, Julianne; Johnson, Robert; Vinson, Joe A

    2012-10-01

    Pre-clinical and clinical studies points to the use of antioxidants as an effective measure to reduce the progression of oxidative stress related disorders. The present study evaluate the effect of three Piper species (Piper guineense, Piper nigrum and Piper umbellatum) for the protection of cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters. Hamsters were classified into eight groups: a normal control, atherogenic control and six other experimental groups (fed atherogenic diet supplemented with different doses of P. nigrum, P. guineense and P. umbellatum (1 and 0.25 g/kg) for 12 weeks. At the end of the feeding period the heart, liver and kidney from each group were analyzed for lipid profile and antioxidant enzymes activities. Atherogenic diet induced a significant (PPiper species significantly inhibited the alteration effect of atherogenic diet on the lipid profile and antioxidant enzymes activities. The Piper extracts may possess an antioxidant protective role against atherogenic diet induced oxidative stress in cardiac, hepatic and renal tissues. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Testosterone 5alpha-reductase inhibitory active constituents of Piper nigrum leaf.

    Science.gov (United States)

    Hirata, Noriko; Tokunaga, Masashi; Naruto, Shunsuke; Iinuma, Munekazu; Matsuda, Hideaki

    2007-12-01

    Previously we reported that Piper nigrum leaf extract showed a potent stimulation effect on melanogenesis and that (-)-cubebin (1) and (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin (2) were isolated as active constituents. As a part of our continuous studies on Piper species for the development of cosmetic hair-care agents, testosterone 5alpha-reductase inhibitory activity of aqueous ethanolic extracts obtained from several different parts of six Piper species, namely Piper nigrum, P. methysticum, P. betle, P. kadsura, P. longum, and P. cubeba, were examined. Among them, the extracts of P. nigrum leaf, P. nigrum fruit and P. cubeba fruit showed potent inhibitory activity. Activity-guided fractionation of P. nigrum leaf extract led to the isolation of 1 and 2. Fruits of P. cubeba contain 1 as a major lignan, thus inhibitory activity of the fruit may be attributable to 1. As a result of further assay on other known constituents of the cited Piper species, it was found that piperine, a major alkaloid amide of P. nigrum fruit, showed potent inhibitory activity, thus a part of the inhibitory activity of P. nigrum fruit may depend on piperine. The 5alpha-reductase inhibitory activities of 1 and piperine were found for the first time. In addition, the P. nigrum leaf extract showed in vivo anti-androgenic activity using the hair regrowth assay in testosterone sensitive male C57Black/6CrSlc strain mice.

  19. Morning employees are perceived as better employees: employees' start times influence supervisor performance ratings.

    Science.gov (United States)

    Yam, Kai Chi; Fehr, Ryan; Barnes, Christopher M

    2014-11-01

    In this research, we draw from the stereotyping literature to suggest that supervisor ratings of job performance are affected by employees' start times-the time of day they first arrive at work. Even when accounting for total work hours, objective job performance, and employees' self-ratings of conscientiousness, we find that a later start time leads supervisors to perceive employees as less conscientious. These perceptions in turn cause supervisors to rate employees as lower performers. In addition, we show that supervisor chronotype acts as a boundary condition of the mediated model. Supervisors who prefer eveningness (i.e., owls) are less likely to hold negative stereotypes of employees with late start times than supervisors who prefer morningness (i.e., larks). Taken together, our results suggest that supervisor ratings of job performance are susceptible to stereotypic beliefs based on employees' start times. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  20. Social constructionism and supervision: experiences of AAMFT supervisors and supervised therapists.

    Science.gov (United States)

    Hair, Heather J; Fine, Marshall

    2012-10-01

    A phenomenological research process was used to investigate the supervision experience for supervisors and therapists when supervisors use a social constructionist perspective. Participants of the one-to-one interviews were six AAMFT Approved Supervisors and six therapists providing counseling to individuals, couples and families. The findings suggest supervisors were committed to their self-identified supervision philosophy and intentionally sought out congruence between epistemology and practice. The shared experience of therapists indicates they associated desirable supervision experiences with their supervisors' social constructionist perspective. Our findings also indicated that supervisors' and therapists' understanding of social constructionism included the more controversial concepts of agency and extra-discursiveness. This research has taken an empirical step in the direction of understanding what the social constructionist supervision experience is like for supervisors and therapists. Our findings suggest a linkage between epistemology and supervision practice and a satisfaction with the supervision process. © 2012 American Association for Marriage and Family Therapy.

  1. LA REPRESENTACION DE LOS COLEGIOS SALESIANOS EN LOS SUPERVISORES NEUQUINOS

    Directory of Open Access Journals (Sweden)

    MARÍA ANDREA NICOLETTI

    2011-10-01

    Full Text Available Nos proponemos analizar en este trabajo de qué manera la identidad entre las escuelas confesionales y los Salesianos, construida desde la época del territorio patagónico, ha marcado fuertemente el discurso de los supervisores escolares que las visitaban. Estos han proyectado una clara representación social sobre la «escuela salesiana», no sólo referencial, sino también prospectiva, en cuanto a que se manifiesta como una construcción inducida. Dentro del sistema educativo patagónico, la educación salesiana ha sido sinónimo de educación confesional, pues fue la única representación de la Iglesia católica en éste ámbito. A través del análisis de los informes de supervisores de las escuelas salesianas neuquinas del período provincial y entrevistas a estos agentes del Consejo, hemos advertido cómo la construcción identitaria (salesianos/escuelas confesionales jugó un rol fundamental en la representación social que los supervisores manifestaron sobre las escuelas de la Congregación, diferenciándolas de las escuelas estatales por su orden, su atención al alumnado y su disciplina. Desde esta perspectiva, la identidad entre las escuelas confesionales y los Salesianos se amplió hacia una analogía que fusionó moral y religión con orden y disciplina, constituyendo una representación social que los supervisores plasmaron en su discurso.

  2. Mobile learning: a workforce development strategy for nurse supervisors.

    Science.gov (United States)

    Mather, Carey; Cummings, Elizabeth

    2014-01-01

    Digital technology provides opportunities for using mobile learning strategies in healthcare environments. To realise the vision of the National Workforce Development Strategy there needs to be innovation of health professionals to further develop knowledge and skills of clinical supervisors to access and gain an understanding of the value of mobile learning at the workplace. The use of digital technology by clinical supervisors was explored in 2012 as part of a teaching development grant to evaluate the use of Web 2.0 technology to develop a community of practice about clinical supervision. Prior to developing the virtual network of clinical supervisors, feedback about the use of Web 2.0 technology by clinicians was sought via an online survey. Over 90% of respondents used social media, 85% understood what a blog and wiki were and approximately half of the respondents used smart phones. More than one-third indicated they would participate in a virtual community of practice and would like to receive information about clinical facilitation at least once per week. Findings indicate both inhibitors and opportunities for workforce development within healthcare environments that need to be addressed. Support of graduate-ready nurses can be achieved through an integrated outlook that enables health professionals within organisations to undertake mobile learning in situ. A flexible and collaborative approach to continuing professional development within organisations could enhance practice development and could positively impact on workforce development.

  3. Profiling of Piper betle Linn. cultivars by direct analysis in real time mass spectrometric technique.

    Science.gov (United States)

    Bajpai, Vikas; Sharma, Deepty; Kumar, Brijesh; Madhusudanan, K P

    2010-12-01

    Piper betle Linn. is a traditional plant associated with the Asian and southeast Asian cultures. Its use is also recorded in folk medicines in these regions. Several of its medicinal properties have recently been proven. Phytochemical analysis showed the presence of mainly terpenes and phenols in betel leaves. These constituents vary in the different cultivars of Piper betle. In this paper we have attempted to profile eight locally available betel cultivars using the recently developed mass spectral ionization technique of direct analysis in real time (DART). Principal component analysis has also been employed to analyze the DART MS data of these betel cultivars. The results show that the cultivars of Piper betle could be differentiated using DART MS data.

  4. Corrosion Inhibition of Mild Steel in Citric Acid by Aqueous Extract of Piper Nigrum L.

    Directory of Open Access Journals (Sweden)

    P. Matheswaran

    2012-01-01

    Full Text Available The inhibition efficiency (IE of an aqueous extract of Piper Nigrum L. in controlling corrosion of mild steel at pH 12 has been evaluated by weight loss method in the absence and presence of inhibitor in citric acid medium at different concentration. The result showed that the corrosion inhibition efficiency of these compounds was found to vary with the different concentration at two hour time interval at room temperature. Also, it was found that the corrosion inhibition behaviour of Piper Nigrum L. is greater in 2 N Citric acid than 1 N Citric acid medium. So Piper Nigrum L. can be used has a good inhibitor for preventing mild steel material which is used in many construction purpose.

  5. ALCALOIDES BENCILISOQUINOLÍNICOS DEL TALLO DE Piper augustum Rudge

    Directory of Open Access Journals (Sweden)

    Wilman Delgado A.

    2010-10-01

    Full Text Available Del extracto etanólico del tallo de P. augustum Rudge se aislaron: 3beta-hidroxi- 24-etil-delta5.22colestadieno (estigmasterol I ; l,2-metilendioxi-6-metil-4H-dibenzo(deg quinolina-4,5(6Hdiona (Cepharadione A II; lactama del ácido lO-amino-3,4- dimetoxifenantreno-1-carboxílico (Cepharanone B n i y el nuevo compuesto natural: lactama del ácido N-metil-lO-amino- 4-hidroxi-2,3-dimetoxifenantreno-1 –carboxílico IV, Todos los compuestos fueron identificados mediante técnicas espectroscópicas (EM, RMN 'H y "C, IR y UV y comparación con datos reportados en la literatura; adicionalmente I y II fueron identificados por comparación con muestras auténticas (CCF, pf, y pf, mixto. El extracto etanólico del tallo de Piper augustum Rudge presentó una moderada actividad biológica (DL50 = 350 ppm según el ensayo de mortalidad de Artemia salina Leach (Brine Shrimp Lethality.

  6. Chemical constituents from Piper hainanense and their cytotoxicities.

    Science.gov (United States)

    Shi, Yan-Ni; Xin, Ying; Ling, Yi; Li, Xing-Cong; Hao, Chao-Yun; Zhu, Hong-Tao; Wang, Dong; Yang, Chong-Ren; Xu, Min; Zhang, Ying-Jun

    2016-08-01

    Two new compounds, (Z,R)-1-phenylethylcinnamate (1) and (1R,2R,3R,6S)-pipoxide (2) were isolated from the aerial part of Piper hainanense, along with 12 known compounds, including nine benzene derivatives (4-11), one isobutylamide (12), and two polyoxygenated cyclohexene derivatives (13-14). Their structures were elucidated on the basis of the HRESIMS, 1D and 2D NMR spectroscopic analyses, and ECD in cases of 2 and 3. The absolute configuration of ellipeiopsol B (3) was determined for the first time. All these compounds 1-14 were reported from the titled plant for the first time. Most of the isolates were tested for their cytotoxicities against five human cancer cell lines. Four of which, 2, 3, 9, 14 showed moderate bioactivities. Among them, the new compound 2 showed potential cytotoxicity against SMMC-7721, MCF-7, and SW-480 with IC50 values of 9.7, 15.0, and 13.2 μM, respectively.

  7. Bioactivity guided isolation of mosquito larvicide fromPiper longum

    Institute of Scientific and Technical Information of China (English)

    Madhu SK; Vijayan VA; Shaukath AK

    2011-01-01

    Objective:To isolate the larvicidal component from the fruits ofPiper longum (P. longum) against the filariasis vector,Culex quinquefasciatus (C. quinquefasciatus).Methods: Pulverized fruits ofP. longum were subjected to soxhlet extraction using series of organic solvents of increasing polarity. All the solvent extracts were verified for their larvicidal efficacy against 4th instar larvae ofC. quinquefasciatus employing standardWHOprocedure. Bioassay-guided fractionation through column chromatography lead to the isolation of a bioactive amide, pipyahyine from the petroleum ether extract.Results: Petroleum ether extract was found to be the most active fraction among all the extracts tested with LC50 andLC90being1.03 and2.04ppm respectively. Whereas, pipyahyine, an isolated component of the same fraction was found to be even more effective than the parent extract in terms ofLC50being0.58 and1.88 ppm respectively. Conclusions: From the results, it is evident thatP. longum can be considered as a powerful arsenal for the control of mosquito population.

  8. Natural Antioxidants: Piper sarmentosum (Kadok) and Morinda elliptica (Mengkudu).

    Science.gov (United States)

    Subramaniam, Vimala; Adenan, Mohd Ilham; Ahmad, Abdull Rashih; Sahdan, Rohana

    2003-03-01

    The antioxidant activity of two edible medicinal plants commonly used in Malaysian traditional medicine i.e. Piper sarmentosum (kadok) and Morinda elliptica (mengkudu) were tested for antioxidant activity. The methanolic leave extracts of kadok and mengkudu, at 250ug/ml, were tested using the Xanthine/Xanthine Oxidase (X/XOD) Superoxide Scavenging assay. Both extracts showed high superoxide scavenging assay, 88% and 80% respectively compared to superoxide dismutase (SOD) standard. The crude extracts were further fractionated using column chromatography and tested for superoxide scavenging activity, to obtain antioxidant active fractions. Two active fractions were obtained from kadok, PsFr6-71.3%, PsFr7-71.3%, and one active fraction from mengkudu, MeFr3-86.6%. These active fractions were compared against 14 phenolic compound standards. After a series of HPLC analysis of samples and standards, a natural antioxidant compound was identified in kadok and mengkudu i.e. Naringenin (4',5,7-Trihydroxyflavanone) with 75.7% superoxide scavenging activity. Naringenin is a highly potent natural antioxidant that has been reported in the raw materials of larch and grapefruit extracts. Thus, kadok and mengkudu which contain Naringenin, could be used as antioxidant dietary supplements.

  9. Bioactive phenylpropanoid analogues from Piper betle L. var. haldia leaves.

    Science.gov (United States)

    Atiya, Akhtar; Sinha, Barij Nayan; Lal, Uma Ranjan

    2017-02-15

    Phytochemical analyses of the chloroform extract of Piper betle L. var. birkoli, Piperaceae, leaves led to the isolation of two new phenylpropanoid analogues: bis-chavicol dodecanoyl ester (2) and bis-hydroxychavicol dodecanoyl ester (3), along with one known compound: allyl-3-methoxy-4-hydroxybenzene (1) on the basis of spectroscopic data 1D ((1)H and (13)C) and 2D ((1)H-(1)H COSY and HMBC) NMR, as well as ESI-MS, FT-IR, HR-ESI-MS and LC-ESI-MS. Compound 2 and 3 exhibited excellent antioxidant DPPH radical scavenging activity with IC50 values of 12.67 μg/mL and 1.08 μg/mL compared to ascorbic acid as a standard antioxidant drug with IC50 value of 6.60 μg/mL. Evaluation of cytotoxic activity against two human oral cancer cell lines (AW13516 and AW8507) showed significant effect with GI50 values of 19.61 and 23.01 μg/mL for compound 2 and 10.25 and 13.12 μg/mL for compound 3, compared to Doxorubicin(®) as a standard cytotoxic drug with GI50 value of < 10 μg/mL.

  10. Piper betle-mediated green synthesis of biocompatible gold nanoparticles

    Science.gov (United States)

    Punuri, Jayasekhar Babu; Sharma, Pragya; Sibyala, Saranya; Tamuli, Ranjan; Bora, Utpal

    2012-08-01

    Here, we report the novel use of the ethonolic leaf extract of Piper betle for gold nanoparticle (AuNP) synthesis. The successful formation of AuNPs was confirmed by UV-visible spectroscopy, and different parameters such as leaf extract concentration (2%), gold salt concentration (0.5 mM), and time (18 s) were optimized. The synthesized AuNPs were characterized with different biophysical techniques such as transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), and energy-dispersive X-ray spectroscopy (EDX). TEM experiments showed that nanoparticles were of various shapes and sizes ranging from 10 to 35 nm. FT-IR spectroscopy revealed that AuNPs were functionalized with biomolecules that have primary amine group -NH2, carbonyl group, -OH groups, and other stabilizing functional groups. EDX showed the presence of the elements on the surface of the AuNPs. FT-IR and EDX together confirmed the presence of biomolecules bounded on the AuNPs. Cytotoxicity of the AuNPs was tested on HeLa and MCF-7 cancer cell lines, and they were found to be nontoxic, indicating their biocompatibility. Thus, synthesized AuNPs have potential for use in various biomedical applications.

  11. Piper betle extracts exhibit antitumor activity by augmenting antioxidant potential.

    Science.gov (United States)

    Alam, Badrul; Majumder, Rajib; Akter, Shahina; Lee, Sang-Han

    2015-02-01

    The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard to antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice and to confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation of tumor cells into mice, extracts were administered at 25, 50 and 100 mg/kg body weight for nine consecutive days. The antitumor effects of the extracts were then assessed according to tumor volume, packed cell count, viable and non-viable tumor cell count, median survival time and increase in life span of EAC-bearing mice. Next, hematological profiles and serum biochemical parameters were calculated, and antioxidant properties were assessed by estimating lipid peroxidation, reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) levels. MPBL and the ethylacetate fraction (EPBL) at a dose of 100 mg/kg induced a significant decrease in tumor volume, packed cell volume and viable cell count and increased the life span of the EAC-bearing mice (PPiper betle extracts exhibit significant antitumor activity, which may be attributed to the augmentation of endogenous antioxidant potential.

  12. Histamine release inhibitory activity of Piper nigrum leaf.

    Science.gov (United States)

    Hirata, Noriko; Naruto, Shunsuke; Inaba, Kazunori; Itoh, Kimihisa; Tokunaga, Masashi; Iinuma, Munekazu; Matsuda, Hideaki

    2008-10-01

    Oral administration of a methanolic extract of Piper nigrum leaf (PN-ext, 50, 200 and 500 mg/kg) showed a potent dose-dependent inhibition of dinitrofluorobenzene (DNFB)-induced cutaneous reaction at 1 h [immediate phase response (IPR)] after and 24 h [late phase response (LPR)] after DNFB challenge in mice which were passively sensitized with anti-dinitrophenyl (DNP) IgE antibody. Ear swelling inhibitory effect of PN-ext (50, 200 and 500 mg/kg, per os (p.o.)) on very late phase response (vLPR) in the model mice was significant but weaker than that on IPR. Oral administration of PN-ext (50, 200 and 500 mg/kg for 7 d) inhibited picryl chloride (PC)-induced ear swelling in PC sensitized mice. PN-ext exhibited in vitro inhibitory effect on compound 48/80-induced histamine release from rat peritoneal mast cells. Two lignans of PN-ext, (-)-cubebin (1) and (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin (2), were identified as major active principles having histamine release inhibitory activity.

  13. Insecticidal Activity of Piperine Isolated from Piper sarmentosum

    Institute of Scientific and Technical Information of China (English)

    Feng; Gang; Ye; Huochun; Yuan; Enlin; Zhang; Jing; Yan; Chao; Jin; Qian; Peng; Zhengqiang; Fu; Yue-guan

    2014-01-01

    In order to clarify the insecticidal active ingredients of Piper sarmentosum,one active ingredient was isolated from ethanol extract of P. sarmentosum by bioassay-guided fractionation method. Its chemical structures were identified to be piperine by MS,1H NMR,13C NMR. The insecticidal activity of piperine and ethanol extract of P. sarmentosum against Aleurodicus dispels Russell were tested by leaf dip method. The results showed that piperine and ethanol extract of P. sarmentosum exhibited strong insecticidal activity against adults and nymphs of A. dispels; LC50values against adults were 28. 59 and 224. 31 mg/L,and LC50values against nymphs were 65. 91 and 336. 68 mg/L,respectively. There was no significant difference between piperine and azadirachtin against adults and nymphs of A.dispels. Therefore,piperine might be one of the main insecticidal ingredients of P. sarmentosum. In addition,piperine and ethanol extract showed ovicidal activity with different mode of action,piperine reduced the survival rate of newly hatched nymphs while ethanol extract impacted hatch of eggs.

  14. Evaluation of genetic diversity in Piper spp using RAPD and SRAP markers.

    Science.gov (United States)

    Jiang, Y; Liu, J-P

    2011-11-29

    Random amplified polymorphic DNA (RAPD) and sequence-related amplified polymorphism (SRAP) analysis were applied to 74 individual plants of Piper spp in Hainan Island. The results showed that the SRAP technique may be more informative and more efficient and effective for studying genetic diversity of Piper spp than the RAPD technique. The overall level of genetic diversity among Piper spp in Hainan was relatively high, with the mean Shannon diversity index being 0.2822 and 0.2909, and the mean Nei's genetic diversity being 0.1880 and 0.1947, calculated with RAPD and SRAP data, respectively. The ranges of the genetic similarity coefficient were 0.486-0.991 and 0.520-1.000 for 74 individual plants of Piper spp (the mean genetic distance was 0.505 and 0.480) and the within-species genetic distance ranged from 0.063 to 0.291 and from 0.096 to 0.234, estimated with RAPD and SRAP data, respectively. These genetic indices indicated that these species are closely related genetically. The dendrogram generated with the RAPD markers was topologically different from the dendrogram based on SRAP markers, but the SRAP technique clearly distinguished all Piper spp from each other. Evaluation of genetic variation levels of six populations showed that the effective number of alleles, Nei's gene diversity and the Shannon information index within Jianfengling and Diaoluoshan populations are higher than those elsewhere; consequently conservation of wild resources of Piper in these two regions should have priority.

  15. Lignans and aromatic glycosides from Piper wallichii and their antithrombotic activities.

    Science.gov (United States)

    Shi, Yan-Ni; Shi, Yi-Ming; Yang, Lian; Li, Xing-Cong; Zhao, Jin-Hua; Qu, Yan; Zhu, Hong-Tao; Wang, Dong; Cheng, Rong-Rong; Yang, Chong-Ren; Xu, Min; Zhang, Ying-Jun

    2015-03-13

    Piper wallichii (Miq.) Hand.-Mazz. is a medicinal plant used widely for the treatment of rheumatoid arthritis, inflammatory diseases, cerebral infarction and angina in China. Previous study showed that lignans and neolignans from Piper spp. had potential inhibitory activities on platelet aggregation. In the present study, we investigated the chemical constituents of Piper wallichii and their antithrombotic activities, to support its traditional uses. The methanolic extract of the air-dried stems of Piper wallichii was separated and purified using various chromatographic methods, including semi-preparative HPLC. The chemical structures of the isolates were determined by detailed spectroscopic analysis, and acidic hydrolysis in case of the new glycoside 2. Determination of absolute configurations of the new compound 1 was facilitated by calculated electronic circular dichroism using time-dependent density-functional theory. All compounds were tested for their inhibitory effects on platelet aggregation induced by platelet activating factor (PAF) in rabbits׳ blood model, from which the active ones were further evaluated the in vivo antithrombotic activity in zebrafish model. A new neolignan, piperwalliol A (1), and four new aromatic glycosides, piperwalliosides A-D (2-5) were isolated from the stems of Piper wallichii, along with 25 known compounds, including 13 lignans, six aromatic glycosides, two phenylpropyl aldehydes, and four biphenyls. Five known compounds (6-10) showed in vitro antiplatelet aggregation activities. Among them, (-)-syringaresinol (6) was the most active compound with an IC50 value of 0.52 mM. It is noted that in zebrafish model, the known lignan 6 showed good in vivo antithrombotic effect with a value of 37% at a concentration of 30 μM, compared with the positive control aspirin with the inhibitory value of 74% at a concentration of 125μM. This study demonstrated that lignans, phenylpropanoid and biphenyl found in Piper wallichii may be

  16. A comparison of leaf crystal macropatterns in the two sister genera Piper and Peperomia (Piperaceae).

    Science.gov (United States)

    Horner, Harry T; Wanke, Stefan; Samain, Marie-Stéphanie

    2012-06-01

    This is the first large-scale study comparing leaf crystal macropatterns of the species-rich sister genera Piper and Peperomia. It focuses on identifying types of calcium oxalate crystals and their macropatterns in leaves of both genera. The Piper results are placed in a phylogenetic context to show evolutionary patterns. This information will expand knowledge about crystals and provide specific examples to help study their form and function. One example is the first-time observation of Piper crystal sand tumbling in chlorenchyma vacuoles. Herbarium and fresh leaves were cleared of cytoplasmic content and examined with polarizing microscopy to identify types of crystals and their macropatterns. Selected hydrated herbarium and fresh leaf punches were processed for scanning electron microscopy and x-ray elemental analysis. Vibratome sections of living Piper and Peperomia leaves were observed for anatomical features and crystal movement. Both genera have different leaf anatomies. Piper displays four crystal types in chlorenchyma-crystal sand, raphides, styloids, and druses, whereas Peperomia displays three types-druses, raphides, and prisms. Because of different leaf anatomies and crystal types between the genera, macropatterns are completely different. Crystal macropattern evolution in both is characterized by increasing complexity, and both may use their crystals for light gathering and reflection for efficient photosynthesis under low-intensity light environments. Both genera have different leaf anatomies, types of crystals and crystal macropatterns. Based on Piper crystals associated with photosynthetic tissues and low-intensity light, further study of their function and association with surrounding chloroplasts is warranted, especially active crystal movement.

  17. Experiments on thermo-hydro-mechanical behaviour of Opalinus Clay at Mont Terri rock laboratory, Switzerland

    Directory of Open Access Journals (Sweden)

    Paul Bossart

    2017-06-01

    Full Text Available Repositories for deep geological disposal of radioactive waste rely on multi-barrier systems to isolate waste from the biosphere. A multi-barrier system typically comprises the natural geological barrier provided by the repository host rock – in our case the Opalinus Clay – and an engineered barrier system (EBS. The Swiss repository concept for spent fuel and vitrified high-level waste (HLW consists of waste canisters, which are emplaced horizontally in the middle of an emplacement gallery and are separated from the gallery wall by granular backfill material (GBM. We describe here a selection of five in-situ experiments where characteristic hydro-mechanical (HM and thermo-hydro-mechanical (THM processes have been observed. The first example is a coupled HM and mine-by test where the evolution of the excavation damaged zone (EDZ was monitored around a gallery in the Opalinus Clay (ED-B experiment. Measurements of pore-water pressures and convergences due to stress redistribution during excavation highlighted the HM behaviour. The same measurements were subsequently carried out in a heater test (HE-D where we were able to characterise the Opalinus Clay in terms of its THM behaviour. These yielded detailed data to better understand the THM behaviours of the granular backfill and the natural host rock. For a presentation of the Swiss concept for HLW storage, we designed three demonstration experiments that were subsequently implemented in the Mont Terri rock laboratory: (1 the engineered barrier (EB experiment, (2 the in-situ heater test on key-THM processes and parameters (HE-E experiment, and (3 the full-scale emplacement (FE experiment. The first demonstration experiment has been dismantled, but the last two ones are on-going.

  18. How Supervisor Experience Influences Trust, Supervision, and Trainee Learning: A Qualitative Study.

    Science.gov (United States)

    Sheu, Leslie; Kogan, Jennifer R; Hauer, Karen E

    2017-09-01

    Appropriate trust and supervision facilitate trainees' growth toward unsupervised practice. The authors investigated how supervisor experience influences trust, supervision, and subsequently trainee learning. In a two-phase qualitative inductive content analysis, phase one entailed reviewing 44 internal medicine resident and attending supervisor interviews from two institutions (July 2013 to September 2014) for themes on how supervisor experience influences trust and supervision. Three supervisor exemplars (early, developing, experienced) were developed and shared in phase two focus groups at a single institution, wherein 23 trainees validated the exemplars and discussed how each impacted learning (November 2015). Phase one: Four domains of trust and supervision varying with experience emerged: data, approach, perspective, clinical. Early supervisors were detail oriented and determined trust depending on task completion (data), were rule based (approach), drew on their experiences as trainees to guide supervision (perspective), and felt less confident clinically compared with more experienced supervisors (clinical). Experienced supervisors determined trust holistically (data), checked key aspects of patient care selectively and covertly (approach), reflected on individual experiences supervising (perspective), and felt comfortable managing clinical problems and gauging trainee abilities (clinical). Phase two: Trainees felt the exemplars reflected their experiences, described their preferences and learning needs shifting over time, and emphasized the importance of supervisor flexibility to match their learning needs. With experience, supervisors differ in their approach to trust and supervision. Supervisors need to trust themselves before being able to trust others. Trainees perceive these differences and seek supervision approaches that align with their learning needs.

  19. A benzoic acid derivative and flavokawains from Piper species as schistosomiasis vector controls.

    Science.gov (United States)

    Rapado, Ludmila N; Freitas, Giovana C; Polpo, Adriano; Rojas-Cardozo, Maritza; Rincón, Javier V; Scotti, Marcus T; Kato, Massuo J; Nakano, Eliana; Yamaguchi, Lydia F

    2014-04-23

    The search of alternative compounds to control tropical diseases such as schistosomiasis has pointed to secondary metabolites derived from natural sources. Piper species are candidates in strategies to control the transmission of schistosomiasis due to their production of molluscicidal compounds. A new benzoic acid derivative and three flavokawains from Piper diospyrifolium, P. cumanense and P. gaudichaudianum displayed significant activities against Biomphalaria glabrata snails. Additionally, "in silico" studies were performed using docking assays and Molecular Interaction Fields to evaluate the physical-chemical differences among the compounds in order to characterize the observed activities of the test compounds against Biomphalaria glabrata snails.

  20. Occurrence, biological activities and 13C NMR data of amides from Piper (Piperaceae

    Directory of Open Access Journals (Sweden)

    Jeferson C. do Nascimento

    2012-01-01

    Full Text Available This manuscript describes an update review with up to 285 references concerning the occurrence of amides from a variety of species of the genus Piper (Piperaceae. Besides addressing occurrence, this review also describes the biological activities attributed to extracts and pure compounds, a compiled 13C NMR data set, the main correlations between structural and NMR spectroscopic data of these compounds, and employment of hyphened techniques such as LC-MS, GC-MS and NMR for analysis of amides from biological samples and crude Piper extracts.

  1. Occurrence, biological activities and {sup 13}C NMR data of amides from Piper (Piperaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Nascimento, Jeferson C. do; Paula, Vanderlucia F. de [Universidade Estadual do Sudoeste da Bahia, Jequie, BA (Brazil). Dept. de Quimica e Exatas; David, Jorge M. [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil). Inst. de Quimica; David, Juceni P., E-mail: jmdavid@ufba.br [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil). Fac. de Farmacia

    2012-07-01

    This manuscript describes an update review with up to 285 references concerning the occurrence of amides from a variety of species of the genus Piper (Piperaceae). Besides addressing occurrence, this review also describes the biological activities attributed to extracts and pure compounds, a compiled {sup 13}C NMR data set, the main correlations between structural and NMR spectroscopic data of these compounds, and employment of hyphened techniques such as LC-MS, GC-MS and NMR for analysis of amides from biological samples and crude Piper extracts. (author)

  2. An Overview of Neolignans of the Genus Piper L.: Isolation Methods and Biological Activities.

    Science.gov (United States)

    Macedo, Arthur Ladeira; Dos Santos, Thais Carvalho Costa; Valverde, Alessandra Leda; Moreira, Davyson de Lima; Vasconcelos, Thatyana Rocha Alves

    2017-01-01

    The genus Piper L. has the shikimic acid pathway predominantly expressed, biosynthesizing many cinnamic acid derivatives (CAD). Neolignans comprise an important class of CAD that exhibit a wide range of pharmacological properties such as antibacterial, antitumor, insecticidal, anti-inflammatory, antioxidant, smooth muscle relaxant, neuroprotective, antiprotozoal and against platelet aggregation factor. These substances have been extracted and isolated from Piper species using different technics. The present review aims to summarize extraction and isolation methods and biological activities of the different types of neolignans covering the period from 1968 to January 2016. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  3. [Volatile Oil Analysis of Piper hongkongense form Different Hatbitats by GC-MS].

    Science.gov (United States)

    Cai, Yi; Xie, Feng-feng; Yan, Ping-hua; Gan, Ri-cheng; Zhu, Hua

    2015-02-01

    To analyze the volatile oil in Piper hongkongense from five different habitats. The volatile oil was analyzed by GC-MS. The volatile components oil of each sample varied significantly. Caryophyllene, α-caryophyllene and nerolidol 2 were common constituents of five samples. The volatile oil and chemical constituent contents of fresh sample were higher than that of the old sample. The volatile oil and chemical constituent contents of Piper hongkongense from different habitats have sig- nificant differences, which are affected by habitats, harvest season, storage time and so on.

  4. Propagação vegetativa de espécies silvestres do gênero Piper, com potencial para uso como porta enxertos em pimenta-do-reino (Piper nigrun Vegetative propagation of wild species of the genus Piper, with potential for use as rootstocks in black pepper (Piper nigrun

    Directory of Open Access Journals (Sweden)

    GC Magevski

    2011-01-01

    Full Text Available O estabelecimento de espécies usadas como porta-enxerto, importantes na olericultura, podem ser multiplicadas por meio da estaquia com auxílio de fitorreguladores. Objetivou-se com este trabalho avaliar a influência do AIB no estabelecimento de espécies nativas do gênero Piper com potencial de uso como porta-enxerto de Piper nigrum. Estacas de P. Arboreum, P. amplum e P. sp foram submetidas a diferentes dosagens de AIB (0, 2000, 4000, 6000 e 8000 mg.L-1 e mantidas em estufa agrícola com irrigação intermitente com temperatura e umidade controlados. O delineamento experimental utilizado foi inteiramente casualizado em esquema fatorial 3x5 (3 espécies de Piper x 5 dosagens de AIB e composto por 3 repetições por tratamento, sendo cada parcela composta por 10 estacas. A avaliação foi realizada aos 45 dias de transplantio e as variáveis analisadas foram: índice de sobrevivência, número médio de folhas, número médio de brotos e comprimento médio do maior broto. A espécie Piper arboreum apresentou bons resultados referentes ao crescimento da parte aérea independentemente da concentração de AIB empregada.The establishment of species used as rootstock, which are important in horticulture crop scan may be multiplied, with the aid of growth regulators, by cutting. The objective of this study was to evaluate the influence of IBA on the establishment of native species of the genus Piper with potential use as rootstock of Piper nigrum. Cuttings of P. arboreum, P. amplum and P. sp were treated with different concentrations of IBA (0 ,2000, 4000, 6000 and 8000mg.L-1 and maintained in a greenhouse with intermittent irrigation, with the temperature and humidity controlled. The experimental design was completely randomized in a factorial 3x5 plan (3 Piper species x5 doses of IBA and comprising of three repetitions per treatment, each plot consisting of 10 cuttings. The evaluation was performed at 45 days of transplanting and the analyzed

  5. GP supervisors' experience in supporting self-regulated learning: a balancing act.

    Science.gov (United States)

    Sagasser, Margaretha H; Kramer, Anneke W M; van Weel, Chris; van der Vleuten, Cees P M

    2015-08-01

    Self-regulated learning is essential for professional development and lifelong learning. As self-regulated learning has many inaccuracies, the need to support self-regulated learning has been recommended. Supervisors can provide such support. In a prior study trainees reported on the variation in received supervisor support. This study aims at exploring supervisors' perspectives. The aim is to explore how supervisors experience self-regulated learning of postgraduate general practitioners (GP) trainees and their role in this, and what helps and hinders them in supervising. In a qualitative study using a phenomenological approach, we interviewed 20 supervisors of first- and third-year postgraduate GP trainees. Supervisors recognised trainee activity in self-regulated learning and adapted their coaching style to trainee needs, occasionally causing conflicting emotions. Supervisors' beliefs regarding their role, trainees' role and the usefulness of educational interventions influenced their support. Supervisors experienced a relation between patient safety, self-regulated learning and trainee capability to learn. Supervisor training was helpful to exchange experience and obtain advice. Supervisors found colleagues helpful in sharing supervision tasks or in calibrating judgments of trainees. Busy practice occasionally hindered the supervisory process. In conclusion, supervisors adapt their coaching to trainees' self-regulated learning, sometimes causing conflicting emotions. Patient safety and entrustment are key aspects of the supervisory process. Supervisors' beliefs about their role and trainees' role influence their support. Supervisor training is important to increase awareness of these beliefs and the influence on their behaviour, and to improve the use of educational instruments. The results align with findings from other (medical) education, thereby illustrating its relevance.

  6. Dimensionality and consequences of employee commitment to supervisors: a two-study examination.

    Science.gov (United States)

    Landry, Guylaine; Panaccio, Alexandra; Vandenberghe, Christian

    2010-01-01

    Research on the 3-component model of organizational commitment--affective, normative, and continuance--has suggested that continuance commitment comprises 2 subcomponents, perceived lack of alternatives and sacrifice (e.g., S. J. Jaros, 1997; G. W. McGee & R. C. Ford, 1987). The authors aimed to extend that research in the context of employees' commitment to their immediate supervisors. Through two studies, they examined the validity and consequences of a 4-factor model of commitment to supervisors including affective, normative, continuance-alternatives, and continuance-sacrifice components. Study 1 (N = 317) revealed that the 4 components of commitment to supervisors were distinguishable from the corresponding components of organizational commitment. Study 2 (N = 240) further showed that the 4 components of commitment to supervisors differentially related to intention to leave the supervisor, supervisor-directed negative affect and emotional exhaustion. The authors discuss the implications of these findings for the management of employee commitment in organizations.

  7. Comparative leaf anatomy of long pepper (Piper hispidinervum C. DC. and spiked pepper (Piper aduncum L. cultured in vitro, ex vitro and in vivo

    Directory of Open Access Journals (Sweden)

    Simone de Alencar Maciel

    2014-12-01

    Full Text Available Piper hispidinervum and Piper aduncum contain the secondary metabolites safrole and dilapiol, and there is commercial interest in their essential oils. The study aimed to compare anatomical aspects related to physiological responses of leaves from P. hispidinervum and P. aduncum propagated in vitro, in vivo and during acclimatization. Paradermal sections and cross-sections of leaves from in vitro, ex vitro and in vivo culture, were obtained for the measurement of anatomical structures using a light microscope. The thickness of the epidermis and hypodermis of P. hispidinervum and P. aduncum underwent changes in the transition from in vitro to ex vitro. Mesophyll tissues and stomatal pore opening of both species were inluenced by the environment in vitro. Different cultivation environments promote the plasticity of the cellular structures of the leaf blade and underlie the success of micropropagation of both species.

  8. A new role-and-feedback system for the supervisor and the organization.

    Science.gov (United States)

    MacStravic, R E

    1990-01-01

    Changes in industry in general and in health care are forcing changes in organizational structures and in people. A new role for supervisors is being demanded as layers of management are reduced to cut costs and simplify operations. The new supervisor will have to be a leader and decisionmaker. The feedback system suggested here provides a mechanism for ensuring that supervisors' leadership is going in the right direction and that their decisions are having the desired effects.

  9. A Comparative Study on Corrosion Inhibition of Mild Steel Using Piper Nigrum L. in Different Acid Medium

    Directory of Open Access Journals (Sweden)

    B. Anand

    2010-01-01

    Full Text Available The inhibition of corrosion of mild steel using Piper nigrum L in different acid medium by weight loss method was investigated. The corrosion inhibition was studied in hydrochloric acid and sulphuric acid by weight loss method at different time interval at room temperature. The result showed that the corrosion inhibition efficiency of this compound was found to vary with different time interval and different acid concentration. Also, it was found that the corrosion inhibition behavior of Piper nigrum L is greater in sulphuric acid than hydrochloric acid. So, Piper nigrum L can be used as a good inhibitor for preventing mild steel material.

  10. 毛巾织机起毛控制凸轮设计%Design of the Loop- pile Controlling Cam of a Terry Towel Loom

    Institute of Scientific and Technical Information of China (English)

    周腊权; 陈明

    2000-01-01

    应用压力角作为凸轮设计时考虑的主要要素,并运用计算机作为辅助手段,设计出毛巾织机起毛控制凸轮的主要参数及绘出凸轮廓线。%The pressure angle was taken to be the primary factor when designing the cam in this paper. And with thehelp of computers, the main elements of the loop - pile controlling cam of terry towel loom and its profile will be obtained.

  11. Les proprietés des Argiles à Opalinus étudiées au laboratoire souterrain du Mont Terri en Suisse

    Science.gov (United States)

    Thury, Marc

    2002-10-01

    In the Mont Terri Rock Laboratory, eleven organisations from six countries (ANDRA and IPSN from France) are investigating jointly a Mesozoic shale formation, the Opalinus Clay. The aims of the research programme are to analyse its hydrogeological, geochemical and rock mechanical properties, the changes induced by the excavation of galleries, by heat-generating waste and by engineered barriers, and to evaluate and improve appropriate investigation techniques. The results of a series of experiments indicate that, at a convenient site, the investigated or similar clay formations could be favourable for hosting a safe repository for radioactive waste. To cite this article: M. Thury, C. R. Physique 3 (2002) 923-933.

  12. Managing organizational change: strategies for the female health care supervisor.

    Science.gov (United States)

    Davies, G

    1990-07-01

    In responding to resistance to change in the current health care organization, the new female supervisor can learn to support her staff in encountering and accepting these changes. The strategies and skills discussed above are characteristic of a supervisory style that may naturally occur for women, but also can be incorporated into the leadership style of men in health care management today. Health care leaders of tomorrow must work from an androgynous framework in which the behavior patterns and responses of each gender are learned and used appropriately by both men and women. Sargent suggests that the best managers are androgynous and that this is the inevitable wave of the future. Whether man or woman, a supervisor should learn, accept, and use methods that are characteristic of both sexes to be successful in managing people. Women and men must learn from each other's strengths and share these diverse skills. Given that women now outnumber men in health care management positions and organizations are changing to a more nurturing environment, the androgynous supervisor will be the successful leader of the future. Finally, women in health care supervisory positions have the potential to bring change where it is badly needed. Women in these roles often have a system wide view of health care policy issues that recognizes less federal commitment to social programs. Many women in health care positions believe that the issues of children, women, the elderly, the poor, and the homeless need focused attention. The growing number of women in health care supervisory and leadership roles is an important factor in changing national health policy for the benefit of these groups.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Relationships among supervisor feedback environment, work-related stressors, and employee deviance.

    Science.gov (United States)

    Peng, Jei-Chen; Tseng, Mei-Man; Lee, Yin-Ling

    2011-03-01

    Previous research has demonstrated that the employee deviance imposes enormous costs on organizational performance and productivity. Similar research supports the positive effect of favorable supervisor feedback on employee job performance. In light of such, it is important to understand the interaction between supervisor feedback environment and employee deviant behavior to streamline organization operations. The purposes of this study were to explore how the supervisor feedback environment influences employee deviance and to examine the mediating role played by work-related stressors. Data were collected from 276 subordinate-supervisor dyads at a regional hospital in Yilan. Structural equation modeling analyses were conducted to test hypotheses. Structural equation modeling analysis results show that supervisor feedback environment negatively related to interpersonal and organizational deviance. Moreover, work-related stressors were found to partially mediate the relationship between supervisor feedback environment and employee deviance. Study findings suggest that when employees (nurses in this case) perceive an appropriate supervisor-provided feedback environment, their deviance is suppressed because of the related reduction in work-related stressors. Thus, to decrease deviant behavior, organizations may foster supervisor integration of disseminated knowledge such as (a) how to improve employees' actual performance, (b) how to effectively clarify expected performance, and (c) how to improve continuous performance feedback. If supervisors absorb this integrated feedback knowledge, they should be in a better position to enhance their own daily interactions with nurses and reduce nurses' work-related stress and, consequently, decrease deviant behavior.

  14. Neurobehavioral and toxicological activities of two potentially CNS-acting medicinal plants of Piper genus.

    Science.gov (United States)

    Lopes, Janaina Jardim; Marx, Camila; Ingrassia, Rafaela; Picada, Jaqueline Nascimento; Pereira, Patrícia; Ferraz, Alexandre de Barros Falcão

    2012-01-01

    Plants from the genus Piper are economically useful and some species have been indicated because of their medicinal properties in the central nervous system. However, few studies about toxicity and neurobehavioral effects have been conducted. In this study, two Piper species, P. amalago and P. mikanianum were investigated in rats to determine acute toxicity and to evaluate the ansiogenic/ansiolytic properties in the elevated plus-maze and the effects on locomotion and exploration in an open field. Additionally, genotoxic activities were evaluated, using the comet assay in several tissues and the micronucleus assay in bone marrow. The phytochemical analysis of both Piper species leaves suggests the presence of amide, essential oils, flavonoids and phenolic compounds. The LD(50) of P. amalago and P. mikanianum were estimated as 2,545 and 1,661 mg/kg, respectively. The behavioral and genotoxic parameters were determined after an intraperitoneal administration of P. amalago (250 or 420 mg/kg) or P. mikanianum (160 or 270 mg/kg). Both plants decreased the number of entries and time spent in the open arms in the plus-maze test, indicating an anxiogenic effect. Only P. mikanianum affected locomotion and exploration in the open field behavior test. No genotoxic or mutagenic effect was observed. Our results suggest that these Piper species act on the central nervous system, without induce genetic toxicity.

  15. Synergistic effects of amides from two piper species on generalist and specialist herbivores.

    Science.gov (United States)

    Richards, Lora A; Dyer, Lee A; Smilanich, Angela M; Dodson, Craig D

    2010-10-01

    Plants use a diverse mix of defenses against herbivores, including multiple secondary metabolites, which often affect herbivores synergistically. Chemical defenses also can affect natural enemies of herbivores via limiting herbivore populations or by affecting herbivore resistance to parasitoids. In this study, we performed feeding experiments to examine the synergistic effects of imides and amides (hereafter "amides") from Piper cenocladum and P. imperiale on specialist (Eois nympha, Geometridae) and generalist (Spodoptera frugiperda, Noctuidae) lepidopteran larvae. Each Piper species has three unique amides, and in each experiment, larvae were fed diets containing different concentrations of single amides or combinations of the three. The amides from P. imperiale had negative synergistic effects on generalist survival and specialist pupal mass, but had no effect on specialist survival. Piper cenocladum amides also acted synergistically to increase mortality caused by parasitoids, and the direct negative effects of mixtures on parasitoid resistance and pupal mass were stronger than indirect effects via changes in growth rate and approximate digestibility. Our results are consistent with plant defense theory that predicts different effects of plant chemistry on generalist versus adapted specialist herbivores. The toxicity of Piper amide mixtures to generalist herbivores are standard bottom-up effects, while specialists experienced the top-down mediated effect of mixtures causing reduced parasitoid resistance and associated decreases in pupal mass.

  16. Validation of a Criterion Referenced Test for Young Handicapped Children: PIPER.

    Science.gov (United States)

    Strum, Irene; Shapiro, Madelaine

    The purpose of this study was to validate the Prescriptive Instructional Program for Educational Readiness (PIPER) for utilization as a criterion referenced test (CRT) among learning disabled children. The program consisted of behavioral objectives and diagnostic and/or mastery tasks and activities for each objective in the area of gross motor…

  17. Lifting the Curse of the Roman: Quintus Horatius Flaccus Meets the Pied Piper of Hamelin.

    Science.gov (United States)

    Blackburn, William

    There are many similarities between Robert Browning's "The Pied Piper of Hamelin" and Lewis Carroll's "Alice in Wonderland" that are seldom noted by literary critics. Both works were begun for the amusement of specific children, both employ a strange subterranean journey as a central device, and both are works of nonsense…

  18. 5,120 Superconducting Bolometers for the PIPER Balloon-Borne CMB Polarization Experiment

    Science.gov (United States)

    Benford, Dominic J.; Chuss, David T.; Hilton, Gene C.; Irwin, Kent D.; Jethava, Nikhil S.; Jhabvala, Christine A.; Kogut, Alan J.; Miller, Timothy M.; Mirel, Paul; Moseley, S. Harvey; Rostem, Karwan; Sharp, Elmer H.; Staguhn, Johannes G.; Stiehl, gregory M.; Voellmer, George M.; Wollack, Edward J.

    2010-01-01

    We are constructing the Primordial Inflation Polarization Explorer (PIPER) to measure the polarization o[ the cosmic microwave background (CMB) and search for the imprint of gravity waves produced during an inflationary epoch in the early universe. The signal is faint and lies behind confusing foregrounds, both astrophysical and cosmological, and so many detectors are required to complete the measurement in a limited time. We will use four of our matured 1,280 pixel, high-filling-factor backshort-under-grid bolometer arrays for efficient operation at the PIPER CMB wavelengths. All four arrays observe at a common wavelength set by passband filters in the optical path. PIPER will fly four times to observe at wavelengths of 1500, 1100, 850, and 500 microns in order to separate CMB from foreground emission. The arrays employ leg-isolated superconducting transition edge sensor bolometers operated at 128mK; tuned resonant backshorts for efficient optical coupling; and a second-generation superconducting quantum interference device (SQUID) multiplexer readout. We describe the design, development, and performance of PIPER bo|ometer array technology to achieve background-limited sensitivity for a cryogenic balloon-borne telescope.

  19. FLAVONOIDES AISLADOS DE LAS INFLORESCENCIAS DE Piper hispidum Kunth (PIPERACEAE Y DERIVADOS ACETILADOS

    Directory of Open Access Journals (Sweden)

    Erika Plazas

    2009-04-01

    Full Text Available En el articulo "FLAVONOIDES AISLADOS DE LAS INFLORESCENCIAS DE Piper hispidum Kunth (PIPERACEAE Y DERIVADOS ACETILADOS" de Erika A. Plazas G., Luis E. Cuca S., Wilman A. Delgado A Rev Colomb. Quim., 2008, 37(2: 135-144 falto incluir lo siguiente.

  20. Caldensinic acid, a benzoic acid derivative and others compounds from Piper carniconnectivum

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Harley da Silva; Souza, Maria de Fatima Vanderlei de; Chaves, Maria Celia de Oliveira, E-mail: cchaves@ltf.ufpb.b [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Lab. de Tecnologia Farmaceutica

    2010-07-01

    A benzoic acid derivative - caldensinic acid, E-phythyl hexadecanoate, {beta}-sitosterol and stigmasterol mixture and phaeophytin a were isolated from the aerial parts of Piper carniconnectivum. The structures of these compounds were established unambiguously by IR, MS, 1D and 2D NMR analysis. (author)

  1. Effectiveness of Piper betle leaf infusion as a palpebral skin antiseptic

    Directory of Open Access Journals (Sweden)

    Husnun Amalia

    2016-02-01

    Full Text Available The goal of an antiseptic is to eliminate or greatly reduce the number of microorganisms in the surgical field at the time of the surgery. The objective of this study was to verify the effectiveness of 20% Piper betle leaf infusion as an antiseptic solution in pre-surgery cataract patients. A clinical trial with partner-matching design was conducted on 31 pairs of eyelids. From each pair of eyelids, one eyelid was asigned to the Piper betle infusion group and the opposite one to the povidone-iodine group. The microorganisms were collected by swab from the patient’s palpebral skin, inoculated on nutrient agar, and incubated at 37oC for 20 hours. The antiseptic effectiveness was measured by counting the microbial colonies before and after administration of the antiseptic solutions. This study demonstrates that the mean colony counts after application of 20% Piper betle leaf infusion showed a significant reduction of 27-100% compared with those before administration (p=0.001. Mean colony counts after 10% povidone-iodine administration showed a significant reduction of 88-100% compared with the mean counts before the solution was applied (p=0.000. The 20% Piper betle infusion has an antiseptic potential. Nevertheless, the 10% povidone-iodine solution has more effective antiseptic capability.

  2. Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle.

    Science.gov (United States)

    Murata, Kazuya; Nakao, Kikuyo; Hirata, Noriko; Namba, Kensuke; Nomi, Takao; Kitamura, Yoshihisa; Moriyama, Kenzo; Shintani, Takahiro; Iinuma, Munekazu; Matsuda, Hideaki

    2009-07-01

    The screening of Piperaceous plants for xanthine oxidase inhibitory activity revealed that the extract of the leaves of Piper betle possesses potent activity. Activity-guided purification led us to obtain hydroxychavicol as an active principle. Hydroxychavicol is a more potent xanthine oxidase inhibitor than allopurinol, which is clinically used for the treatment of hyperuricemia.

  3. REPELLENCY OF ESSENTIAL OIL OF PIPER ADUNCUM AGAINST AEDES ALBOPICTUS IN THE LABORATORY

    NARCIS (Netherlands)

    Misni, Norashiqin; Sulaiman, Sallehudin; Othman, Hidayatulfathi; Omar, Baharudin

    2009-01-01

    The repellent activity of Piper aduncum essential oil against Aedes albopictus was investigated under laboratory conditions with human volunteers. The lowest median effective dose (ED(50)) value was 1.5 mu g/cm(2) at 60 sec of exposure when compared to 90 see (2.1 mu g/cm(2)) and 120 see (1.8 mu g/c

  4. Use of a Robotic Sampler (PIPER) for Evaluation of Particulate Matter Exposure and Eczema in Preschoolers.

    Science.gov (United States)

    Shah, Lokesh; Mainelis, Gediminas; Ramagopal, Maya; Black, Kathleen; Shalat, Stuart L

    2016-02-19

    While the association of eczema with asthma is well recognized, little research has focused on the potential role of inhalable exposures and eczema. While indoor air quality is important in the development of respiratory disease as children in the U.S. spend the majority of their time indoors, relatively little research has focused on correlated non-respiratory conditions. This study examined the relationship between particulate matter (PM) exposures in preschool age children and major correlates of asthma, such as wheeze and eczema. Air sampling was carried out using a robotic (PIPER) child-sampling surrogate. This study enrolled 128 participants, 57 male and 71 female children. Ages ranged from 3 to 58 months with the mean age of 29.3 months. A comparison of subjects with and without eczema showed a difference in the natural log (ln) of PM collected from the PIPER air sampling (p = 0.049). PIPER's sampling observed an association between the ln PM concentrations and eczema, but not an association with wheezing history in pre-school children. Our findings are consistent with the hypothesis of the role of the microenvironment in mediating atopic dermatitis, which is one of the predictors of persistent asthma. Our findings also support the use of PIPER in its ability to model and sample the microenvironment of young children.

  5. Benzoic acid derivatives from Piper species and their fungitoxic activity against Cladosporium cladosporioides and C. sphaerospermum.

    Science.gov (United States)

    Lago, João Henrique G; Ramos, Clécio Sousa; Casanova, Diego Campos C; Morandim, Andreia de A; Bergamo, Debora Cristina B; Cavalheiro, Alberto J; Bolzani, Vanderlan da S; Furlan, Maysa; Guimarães, Elsie F; Young, Maria Claudia M; Kato, Massuo J

    2004-11-01

    Piper crassinervium, P. aduncum, P. hostmannianum, and P. gaudichaudianum contain the new benzoic acid derivatives crassinervic acid (1), aduncumene (8), hostmaniane (18), and gaudichaudianic acid (20), respectively, as major secondary metabolites. Additionally, 19 known compounds such as benzoic acids, chromenes, and flavonoids were isolated and identified. The antifungal activity of these compounds was evaluated by bioautographic TLC assay against Cladosporium cladosporioides and C. sphaerospermum.

  6. Quantitative HPLC analysis of some marker compounds of hydroalcoholic extracts of Piper aduncum L

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Laura C.P.; Nunomura, Sergio M. [Instituto Nacional de Pesquisas da Amazonia (INPA), Manaus, AM (Brazil). Coordenacao de Pesquisas em Produtos Naturais]. E-mail: smnunomu@inpa.gov.br; Mause, Robert [Siema Eco Essencias da Amazonia Ltda., Manaus, AM (Brazil)

    2005-11-15

    High performance liquid chromatography is one of the major analytical techniques used in the quality control of phytotherapics. This work describes a HPLC method used to determine the major components present in different hydroalcoholic extracts of aerial parts of Piper aduncum. (author)

  7. REPELLENCY OF ESSENTIAL OIL OF PIPER ADUNCUM AGAINST AEDES ALBOPICTUS IN THE LABORATORY

    NARCIS (Netherlands)

    Misni, Norashiqin; Sulaiman, Sallehudin; Othman, Hidayatulfathi; Omar, Baharudin

    2009-01-01

    The repellent activity of Piper aduncum essential oil against Aedes albopictus was investigated under laboratory conditions with human volunteers. The lowest median effective dose (ED(50)) value was 1.5 mu g/cm(2) at 60 sec of exposure when compared to 90 see (2.1 mu g/cm(2)) and 120 see (1.8 mu

  8. Lifting the Curse of the Roman: Quintus Horatius Flaccus Meets the Pied Piper of Hamelin.

    Science.gov (United States)

    Blackburn, William

    There are many similarities between Robert Browning's "The Pied Piper of Hamelin" and Lewis Carroll's "Alice in Wonderland" that are seldom noted by literary critics. Both works were begun for the amusement of specific children, both employ a strange subterranean journey as a central device, and both are works of nonsense…

  9. Sarmentine, a natural herbicide from Piper species with multiple herbicide mechanisms of action

    Science.gov (United States)

    Sarmentine, 1-(1-pyrrolidinyl)-(2E,4E)-2,4-decadien-1-one, is a natural amide isolated from the fruits of Piper species. The compound has a number of interesting biological properties, including its broad-spectrum activity on weeds as a contact herbicide. Initial studies highlighted a similarity in ...

  10. Mechanical Design of a 4-Stage ADR for the PIPER mission

    Science.gov (United States)

    James, Bryan L.; Kimball, Mark O.; Shirron, Peter J.; Sampson, Michael A.; Letmate, Richard V.; Jackson, Michael L.

    2017-01-01

    The four 1,280 bolometer detector arrays that will fly on the balloon borne PIPER mission will be cooled by a 4-stage adiabatic demagnetization refrigerator (ADR). Two of the three mechanically independent ADR assemblies provide thermal isolation to their salt pills through Kevlar suspensions while the other provides thermal isolation to its salt pill through the use of bellows and Vespel material. The ADR integrates with the detector arrays and it sits in a large bucket Dewar containing superfluid liquid helium. This paper will describe the complex mechanical design of the PIPER ADR, and summarize the mechanical analysis done to validate the design.The four 1,280 bolometer detector arrays that will fly on the balloon borne PIPER mission will be cooled by a 4-stage adiabatic demagnetization refrigerator (ADR). Two of the three mechanically independent ADR assemblies provide thermal isolation to their salt pills through Kevlar suspensions while the other provides thermal isolation to its salt pill through the use of bellows and Vespel material. The ADR integrates with the detector arrays and it sits in a large bucket Dewar containing superfluid liquid helium. This paper will describe the complex mechanical design of the PIPER ADR, and summarize the mechanical analysis done to validate the design.

  11. Genecology of Thurber’s needlegrass (Achnatherum thurberianum (Piper) Barkworth) in the Western U.S.

    Science.gov (United States)

    Thurber’s needlegrass (Achnatherum thurberianum (Piper) Barkworth) is a key restoration species in the Great Basin and surrounding areas, yet comprehensive studies of how climate relates to genetic variation and seed zones for restoration projects are lacking. Potentially adaptive phenotypic traits...

  12. 5,120 Superconducting Bolometers for the PIPER Balloon-Borne CMB Polarization Experiment

    Science.gov (United States)

    Benford, Dominic J.; Chuss, David T.; Hilton, Gene C.; Irwin, Kent D.; Jethava, Nikhil S.; Jhabvala, Christine A.; Kogut, Alan J.; Miller, Timothy M.; Mirel, Paul; Moseley, S. Harvey; hide

    2010-01-01

    We are constructing the Primordial Inflation Polarization Explorer (PIPER) to measure the polarization o[ the cosmic microwave background (CMB) and search for the imprint of gravity waves produced during an inflationary epoch in the early universe. The signal is faint and lies behind confusing foregrounds, both astrophysical and cosmological, and so many detectors are required to complete the measurement in a limited time. We will use four of our matured 1,280 pixel, high-filling-factor backshort-under-grid bolometer arrays for efficient operation at the PIPER CMB wavelengths. All four arrays observe at a common wavelength set by passband filters in the optical path. PIPER will fly four times to observe at wavelengths of 1500, 1100, 850, and 500 microns in order to separate CMB from foreground emission. The arrays employ leg-isolated superconducting transition edge sensor bolometers operated at 128mK; tuned resonant backshorts for efficient optical coupling; and a second-generation superconducting quantum interference device (SQUID) multiplexer readout. We describe the design, development, and performance of PIPER bo|ometer array technology to achieve background-limited sensitivity for a cryogenic balloon-borne telescope.

  13. Validation of a Criterion Referenced Test for Young Handicapped Children: PIPER.

    Science.gov (United States)

    Strum, Irene; Shapiro, Madelaine

    The purpose of this study was to validate the Prescriptive Instructional Program for Educational Readiness (PIPER) for utilization as a criterion referenced test (CRT) among learning disabled children. The program consisted of behavioral objectives and diagnostic and/or mastery tasks and activities for each objective in the area of gross motor…

  14. Effectiveness and safety of botanical pesticides applied in black pepper (Piper nigrum) plantations

    NARCIS (Netherlands)

    Wiratno,

    2008-01-01

    Black pepper (Piper nigrum L) is an important commodity of Indonesia, which has been cultivated since the 6th century. The plant plays an important role in local economies since 95% of the plantations are cultivated by smallholder farmers. Because of this important economic value, proper plant

  15. Antispermatogenic and antifertility effects of fruits of Piper nigrum L. in mice.

    Science.gov (United States)

    Mishra, Raghav Kumar; Singh, Shio Kumar

    2009-09-01

    Effect of oral administration (25 and 100 mg/kg body wt/day, for 20 and 90 days) of fruit powder of Piper nigrum L. on the male reproductive organs of mice, Parkes strain, was investigated. Various reproductive end points such as organs weight, histopathology, sperm parameters, sialic acid and fructose contents, and fertility indices were assessed. Histologically, testes in treated mice, except in those treated with 100 mg of dose for 90 days, showed non-uniform degenerative changes in the seminiferous tubules, as both affected and normal tubules were observed in the same section. In mice treated with 100 mg dose for 90 days, degenerative changes were observed in all the tubules. Affected seminiferous tubules showed intraepithelial vacuolation, loosening of germinal epithelium, occurrence of giant cells, and mixing of spermatids of different stages of spermatogenesis; in severe cases, the tubules were lined by mainly a layer of Sertoli cells. Percentage of affected tubules in testes of Piper-treated mice was dose-and duration-related. Further, Piper nigrum treatment for 20 days did not cause appreciable alterations in histological appearance of the epididymis, while the treatment for 90 days caused detectable alterations in the duct. The treatment also had adverse effects on sperm parameters, levels of sialic acid and fructose, and on litter size. Fifty six days after cessation of treatment, the alterations induced in the reproductive organs recovered to control levels, though the litter size in females impregnated by Piper-treated males remained significantly decreased compared to controls.

  16. A new natural product and insecticidal amides from seeds of Piper nigrum Linn.

    Science.gov (United States)

    Siddiqui, Bina S; Gulzar, Tahsin; Begum, Sabira; Afshan, Farhana; Sultana, Razia

    2008-01-01

    Studies on the petroleum ether soluble and insoluble fraction of ethanol extract of dried ground seeds of Piper nigrum resulted in the isolation and structure elucidation of 1 new and 11 known compounds which include 3 hitherto unreported constituents, namely, cinnamylideneacetone, 3,4-methylenedioxyphenylpropiophenone and 2-hydroxy-4,5-methylenedioxypropiophenone from this plant.

  17. Effectiveness and safety of botanical pesticides applied in black pepper (Piper nigrum) plantations

    NARCIS (Netherlands)

    Wiratno,

    2008-01-01

    Black pepper (Piper nigrum L) is an important commodity of Indonesia, which has been cultivated since the 6th century. The plant plays an important role in local economies since 95% of the plantations are cultivated by smallholder farmers. Because of this important economic value, proper plant produ

  18. Effectiveness of Piper betle leaf infusion as a palpebral skin antiseptic

    Directory of Open Access Journals (Sweden)

    Husnun Amalia

    2009-08-01

    Full Text Available The goal of an antiseptic is to eliminate or greatly reduce the number of microorganisms in the surgical field at the time of the surgery. The objective of this study was to verify the effectiveness of 20% Piper betle leaf infusion as an antiseptic solution in pre-surgery cataract patients. A clinical trial with partner-matching design was conducted on 31 pairs of eyelids. From each pair of eyelids, one eyelid was asigned to the Piper betle infusion group and the opposite one to the povidone-iodine group. The microorganisms were collected by swab from the patient’s palpebral skin, inoculated on nutrient agar, and incubated at 37oC for 20 hours. The antiseptic effectiveness was measured by counting the microbial colonies before and after administration of the antiseptic solutions. This study demonstrates that the mean colony counts after application of 20% Piper betle leaf infusion showed a significant reduction of 27-100% compared with those before administration (p=0.001. Mean colony counts after 10% povidone-iodine administration showed a significant reduction of 88-100% compared with the mean counts before the solution was applied (p=0.000. The 20% Piper betle infusion has an antiseptic potential. Nevertheless, the 10% povidone-iodine solution has more effective antiseptic capability.

  19. Piper and Vismia Species from Colombian Amazonia Differentially Affect Cell Proliferation of Hepatocarcinoma Cells

    Directory of Open Access Journals (Sweden)

    Leandro J. Lizcano

    2014-12-01

    Full Text Available There is an increasing interest to identify plant-derived natural products with antitumor activities. In this work, we have studied the effects of aqueous leaf extracts from Amazonian Vismia and Piper species on human hepatocarcinoma cell toxicity. Results showed that, depending on the cell type, the plants displayed differential effects; thus, Vismia baccifera induced the selective killing of HepG2, while increasing cell growth of PLC-PRF and SK-HEP-1. In contrast, these two last cell lines were sensitive to the toxicity by Piper krukoffii and Piper putumayoense, while the Piperaceae did not affect HepG2 growth. All the extracts induced cytotoxicity to rat hepatoma McA-RH7777, but were innocuous (V. baccifera at concentrations < 75 µg/mL or even protected cells from basal death (P. putumayoense in primary cultures of rat hepatocytes. In every case, cytotoxicity was accompanied by an intracellular accumulation of reactive oxygen species (ROS. These results provide evidence for the anticancer activities of the studied plants on specific cell lines and suggest that cell killing could be mediated by ROS, thus involving mechanisms independent of the plants free radical scavenging activities. Results also support the use of these extracts of the Vismia and Piper genera with opposite effects as a model system to study the mechanisms of the antitumoral activity against different types of hepatocarcinoma.

  20. ATLAS EventIndex Data Collection Supervisor and Web Interface

    CERN Document Server

    Garcia Montoro, Carlos; The ATLAS collaboration

    2016-01-01

    The EventIndex project consists in the development and deployment of a complete catalogue of events for the ATLAS experiment at the LHC accelerator at CERN. In 2015 the ATLAS experiment has produced 12 billion real events in 1 million files, and 5 billion simulated events in 8 million files. The ATLAS EventIndex is running in production since mid- 2015, reliably collecting information worldwide about all produced events and storing them in a central Hadoop infrastructure. A subset of this information is copied to an Oracle relational database. These slides present two components of the ATLAS EventIndex: its data collection supervisor and its web interface partner.

  1. Integration of Lower Level Supervisors into the Management Structure.

    Science.gov (United States)

    1981-08-31

    sessions. Brief (2-3 hour) training "work sessions" could be developed to help lower level supervisors 4 solve specific problema . These sessions...34 In D. Cartwright (ed.), Studies in Social Power. Ann Arbor, MI: The University of Michigan Press, 1959. Gardner, B.B. & Whyte, W.F. "The man in the...line supervisory problem redefined." Personnel Journal, 1975, 54(12), 620-623+. Stouffer, S.A. "An analysis of conflicting social norms." American

  2. Excavation Induced Hydraulic Response of Opalinus Clay - Investigations of the FE-Experiment at the Mont Terri URL in Switzerland

    Science.gov (United States)

    Vogt, T.; Müller, H. R.; Garitte, B.; Sakaki, T.; Vietor, T.

    2013-12-01

    The Full-Scale Emplacement (FE) Experiment at the Mont Terri underground research laboratory in Switzerland is a full-scale heater test in a clay-rich formation (Opalinus Clay). Based on the Swiss disposal concept it simulates the construction, emplacement, backfilling, and post-closure thermo-hydro-mechanical (THM) evolution of a spent fuel / vitrified high-level waste (SF / HLW) repository tunnel in a realistic manner. The main aim of this experiment is to investigate SF / HLW repository-induced THM coupled effects mainly in the host rock but also in the engineered barrier system (EBS), which consists of bentonite pellets and blocks. A further aim is to gather experience with full-scale tunnel construction and associated hydro-mechanical (HM) processes in the host rock. The entire experiment implementation (in a 50 m long gallery with approx. 3 m diameter) as well as the post-closure THM evolution will be monitored using a network of several hundred sensors (state-of-the-art sensors and measurement systems as well as fiber-optic sensors). The sensors are distributed in the host rock's near- and far-field, the tunnel lining, the EBS, and on the heaters. The heater emplacement and backfilling has not started yet, therefore only the host rock instrumentation is installed at the moment and is currently generating data. We will present the instrumentation concept and rationale as well as the first monitoring results of the excavation and ventilation phase. In particular, we investigated the excavation induced hydraulic response of the host rock. Therefore, the spatiotemporal evolution of porewater-pressure time series was analyzed to get a better understanding of HM coupled processes during and after the excavation phase as well as the impact of anisotropic geomechanic and hydraulic properties of the clay-rich formation on its hydraulic behavior. Excavation related investigations were completed by means of inclinometer data to characterize the non-elastic and time

  3. Determination of the thermal conductivity of opalinus clay via simulations of experiments performed at the Mont Terri underground laboratory

    Science.gov (United States)

    Mügler, C.; Filippi, M.; Montarnal, Ph.; Martinez, J.-M.; Wileveau, Y.

    2006-02-01

    Storage in deep geological formations is a potential solution for the management of high-level radioactive wastes. In this context, different types of rocks such as argillite are extensively studied. In the Mont Terri underground laboratory (Switzerland), several experiments have been performed in order to characterize the properties of the opalinus clay. One of these experiments, called HE-C, has consisted in measuring in situ the time evolution of the rock temperature submitted to a heating source. Experimental measurements have shown that the thermal behaviour of the clay was not homogeneous around the borehole where the heater was installed. Furthermore, 3D direct numerical simulations of this experiment performed with the code Cast3M have proved that it was necessary to introduce a new parameter α to model the amount of electric power lost in cables and by air convection inside the metallic tube containing the heater. A numerical simulation-optimization technique has been used to estimate the thermal longitudinal and transverse conductivities ( λ// and λ⊥) of the host rock. It consists in minimizing an objective function that is the sum of the squared differences between measured and calculated temperatures. But this method induced a lot of Cast3M simulations. In order to drastically reduce the CPU time, we used a neural network approximation built from a sample training of 1100 Cast3M simulations. It allowed us to calculate the objective function for 500 000 different values of the triplet ( λ//, λ⊥, α). Finally, we obtained the following values for the thermal conductivities on one side of the borehole, λ// = 1.84 ± 0.04 W m - 1 K - 1 and λ⊥ = 0.55 ± 0.03 W m - 1 K - 1 ; on the other side, λ// = 1.90 ± 0.07 W m - 1 K - 1 and λ⊥ = 1.07 ± 0.09 W m - 1 K - 1 . The estimated thermal conductivities λ⊥ perpendicular to the bedding plane are quite different. It is perhaps caused by the presence of an intensive fractured zone on one side of

  4. Relationship of species Piper based on morphological and leaf essential oils characters in Yogyakarta

    Directory of Open Access Journals (Sweden)

    PURNOMO

    2005-01-01

    Full Text Available Some of Piper species were used for traditional medicines and condiments. The leaf essential oil (terpenoid of those Piper species usually were used as a main component in traditional medicine. The taxonomycal study was aimed to determined Piper species relationships based on morphological and leaf essential oils characters. The plants were obtained by exploring this province, and samples were collected for identification and leaf essential oils isolation purposes. Species identification were carried out based on identification key (Backer and Bakhuizen v.d. Brink, 1965; Heyne, 1987; Shaorong, 1982. The isolation of leaf essential oils was carried out using Stahl destillation method, and their composition were interpreted with liquid gas chromatography, using caryophyllene and -pinene as a standard of essential oils component. Dendrogram, which showed phenetic relationships among those species, were obtained by hierarchical cluster analysis method. Results of the research showed that there were 8 species found as cultivated plants in Yogyakarta, which were P. miniatum Bl., P. betle L., P. recurvum Bl., P. aduncum L., P. nigrum L., P. cubeba L.f., P. retrofractum Vahl., and P. sarmentosum Roxb. Ex Hunter. Relationship between species of Piper based on morphological character showed that P. aduncum and P. sarmentosum at the same cluster on 69.2% similarity level, and 40.4% similarity level to the other clusters. Relationsips between species of Piper based on leaf essential oils character resulted the difference cluster among the species, P. retrofractum separated from the other species at 45.5% similarity level, P. aduncum and P. cubeba indicated the higest similarity level (81.5%.

  5. Mont Terri Project - Ventilation experiment in Opalinus Clay for the disposal of radioactive waste in underground repositories

    Energy Technology Data Exchange (ETDEWEB)

    Mayor, J. C. [Empresa Nacional de Residuos Radioactivos SA (ENRESA), Madrid (Spain); Garcia-Sineriz, J. [Asociacion para la Investigacion y Desarollo Industrial de los Recursos Naturales (AITEMIN), Madrid (Spain); Velasco, M. [DM Iberia SA, Madrid (Spain); Gomez-Hernandez, J. [Ingenieria Hidraulica y Medio Ambiente, Escuela de Ingenieros de Caminos (UPV), Valencia (Spain); Lloret, A.; Matray, J.-M. [IRSN/DEI/SARG/LETS, Fontenay-aux-Roses (France); Coste, F. [Aradis ESG, Sevres Cedex (France); Giraud, A. [LAEGO-ENSG, Vandoeuvre les Nancy (France); Rothfuchs, T. [Gesellschaft fuer Anlagen und Reaktorsicherheit mbH (GRS), Braunschweig (Germany); Marschall, P. [National Cooperative for the Disposal of Radioactive Waste (Nagra), Wettingen (Switzerland); Roesli, U. [Solexperts AG, Moenchaltorf (Switzerland); Mayer, G. [Colenco Power Engineering Ltd, Baden (Switzerland)

    2007-07-01

    The ventilation of the underground drifts during the construction and operation of a radioactive waste repository could produce the partial desaturation of the rock around the drifts, modifying its thermo-hydro-mechanical properties, especially in clayey rocks. This change of rock properties may have an impact on the design of the repositories (drifts spacing and repository size), which depends on the thermal load that the clay barrier and the rock can accept. To evaluate 'in situ' and better understand the desaturation process of a hard clay formation, the Ventilation Experiment (VE) has been carried out at the Mont Terri underground laboratory (Switzerland), generating a flow of dry air during several months along a section of a microtunnel. Specifically, the VE test has been performed, under practically isothermal conditions (T {approx_equal} 15-16 {sup o}C), in a 10 m long section of a non-lined horizontal microtunnel (diameter = 1.3 m), excavated in 1999 in the shaly facies of the Opalinus Clay of Mont Terri. The microtunnel is oriented perpendicular to the bedding strike direction of the rock (mean value of the bedding dip {approx_equal} 25{sup o}). The VE experiment real data and its modelling have shown that the desaturation of clayey rocks of low hydraulic conductivity (K < 10{sup -12} m/s) due to ventilation is very small. Under real repository conditions, the thermal and hydro-mechanical rock characteristics will not be practically affected by the ventilation. Specifically, the monitoring of the VE test (mainly the hygrometer data, confirmed also by the geoelectrical measurements) indicates that, after about 5 months of ventilation with almost dry air, the rock relative humidity (and then the degree of saturation) was less than 95% only in a ring of thickness less than 40 cm. Nevertheless, a suction state (subatmospheric liquid pressures) developed up to a distance of about 2 m, but it should be kept in mind that a clayey rock such as the

  6. State liberalism, female supervisors, and the gender wage gap.

    Science.gov (United States)

    Maume, David J; Ruppanner, Leah

    2015-03-01

    Whereas some are concerned that the gender revolution has stalled, others note the rapid increase in women's representation in the ranks of management, and the reduction of wage inequality in larger and more active welfare states. Although these latter trends portend an attenuation of gender inequality, their effects on the gender pay gap in the U.S. are understudied due to data limitations, or to the assumption that in the U.S. pay is determined by market forces. In this study we extend research on the determinants of the gender wage gap by examining sex-of-supervisor effects on subordinates' pay, and to what degree the state's commitment to equality conditions this relationship. We pooled the 1997 and 2002 National Study of the Changing Workforce surveys to estimate hierarchical models of reporting to a female supervisor and wages, with theoretically important predictors at the individual level, and at the state of residence (an index composed of women's share of legislators, a measure of the liberal leanings of the state, and the size of the public sector relative to the labor force). We found that state effects on pay were mixed, with pay generally rising with state liberalism on the one hand. On the other hand, working for a female boss significantly reduced wages. We discussed the theoretical implications of our results, as well as the need for further study of the career effects on subordinates as women increasingly enter the ranks of management.

  7. Program to prepare school level supervisors for professional pedagogical guidance.

    Directory of Open Access Journals (Sweden)

    Isdarey Hernández González

    2014-09-01

    Full Text Available Doing an appropriate professional pedagogical guidance becomes a social problem of top priority, due to the fact that when students get to Ninth Grade they face, for the first time, the chance to select a school to continue his studies. However, there are barriers around this social task; like the lack of schools staff preparation and particularly that of the school level supervisors who should lead the School Grade Boards, among its functions are to plan actions for labour and vocational development and also for the professional pedagogical guidance. This article is a result of a research activity carried out by the author who is a Ph. D. Candidate on Pedagogical Sciences. This investigation has as an objective to propose a developmental program to increase the school level supervisors preparation on the professional pedagogical guidance in Junior High School. This program is conceived as a system and starts with an upgrade course, goes on with workshops and ends with a training course. Its main axis is the research method acquisition. This program was carried out through pedagogical practice and showed its efficiency.

  8. SUPERVISOR COMMUNICATION IN TRAINING PROGRAM: AN EMPIRICAL STUDY IN MALAYSIA

    Directory of Open Access Journals (Sweden)

    Azman ISMAIL

    2009-01-01

    Full Text Available A thorough review of human resource development literature shows that theability of supervisors to use good communication styles in managingprograms will invoke employees’ motivation to learn, this may lead toincreased positive individual attitudes and behaviors. The nature of thisrelationship is interesting, but little is known about the influence ofemployees’ motivation to learn in training management literature. Therefore,this study was conducted to examine the effect of supervisor communicationin training program and motivation to learn on individual attitudes andbehaviors using 100 usable questionnaires gathered from technicalemployees who have worked in one city based local authority in EastMalaysia (CLAEASTMALAYSIA. Outcomes of stepwise regression analysisshowed that relationship between motivation to learn and supervisorcommunication had been an important predictor of transfer of competencyand job performance. Statistically, this result confirms that motivation to learndoes act as a full mediating role in the training model of the in theorganizational sample. In addition, implications and limitations of the study,as well as directions future research are discussed.

  9. Knitting Technology and Developing Trends of Warp-knitted Terry Fabrics for Cleaning Uses%清洁用经编毛圈织物的工艺及发展方向

    Institute of Scientific and Technical Information of China (English)

    缪旭红; 戴小莲; 沈建新

    2015-01-01

    The paper introduces the production process and characteristics of warp-knitted terry fabrics. It indi-cates that the machine for producing single faced terry fabric has plush sinker, tricot towel machine and double-side terry fabric knitting machine is used to produce double-faced terry fabric. There are two applications for warp-knitted terry fabric used for cleaning, one is household, and the other is for industrial. Because different applica-tion has different requirements on cleaning performance, it should choose the materials according to the use of fab-rics. At last, the paper predicts the prospect of warp-knitted terry fabric for cleaning uses, which are specializa-tion, decoration and functionalization.%介绍经编毛圈织物的生产方法和特点,指出生产单面毛圈织物的机器带有毛圈沉降片;生产双面毛圈织物的设备主要有特里科毛巾机和双面毛圈钩编机。经编毛圈织物在清洁领域的应用分为家用和产业用,不同的应用场合对毛圈织物的清洁性能有不同的要求,设计时需要根据织物的用途选择原料。最后阐述经编毛圈类清洁织物未来可能的发展方向:专业化、装饰化和功能化。

  10. Fur-rubbing with Piper leaves in the San Martín titi monkey, Callicebus oenanthe

    Directory of Open Access Journals (Sweden)

    R. Huashuayo-Llamocca

    2017-06-01

    Full Text Available We report observations on fur-rubbing with leaves from Piper aduncum by a San Martín titi monkey, Callicebus oenanthe. Fur-rubbing occurred during the transition from the dry to the rainy season in a titi monkey group living in a forest fragment in the Moyobamba region of Peru. Since Piper leaves include very potent compounds that may affect ectoparasites, we tentatively interpret the observed fur-rubbing as self-medication.

  11. Antiparasitic activity of prenylated benzoic acid derivatives from Piper species.

    Science.gov (United States)

    Flores, Ninoska; Jiménez, Ignacio A; Giménez, Alberto; Ruiz, Grace; Gutiérrez, David; Bourdy, Genevieve; Bazzocchi, Isabel L

    2009-03-01

    Fractionation of dichloromethane extracts from the leaves of Piper heterophyllum and P. aduncum afforded three prenylated hydroxybenzoic acids, 3-[(2E,6E,10E)-11-carboxy-3,7,15-trimethyl-2,6,10,14-hexadecatetraenyl)-4,5-dihydroxybenzoic acid, 3-[(2E,6E,10E)-11-carboxy-13-hydroxy-3,7,15-trimethyl-2,6,10,14-hexadecatetraenyl]-4,5-dihydroxybenzoic acid and 3-[(2E,6E,10E)-11-carboxy-14-hydroxy-3,7,15-trimethyl-2,6,10,15-hexadecatetraenyl]-4,5-dihydroxybenzoic acid, along with the known compounds, 4,5-dihydroxy-3-(E,E,E-11-formyl-3,7,15-trimethyl-hexadeca-2,6,10,14-tetraenyl)benzoic acid (arieianal), 3,4-dihydroxy-5-(E,E,E-3,7,11,15-tetramethyl-hexadeca-2,6,10,14-tetraenyl)benzoic acid, 4-hydroxy-3-(E,E,E-3,7,11,15-tetramethyl-hexadeca-2,6,10,14-tetraenyl)benzoic acid, 3-(3,7-dimethyl-2,6-octadienyl)-4-methoxy-benzoic acid, 4-hydroxy-3-(3,7-dimethyl-2,6-octadienyl)benzoic acid and 4-hydroxy-3-(3-methyl-1-oxo-2-butenyl)-5-(3-methyl-2-butenyl)benzoic acid. Their structures were elucidated on the basis of spectroscopic data, including homo- and heteronuclear correlation NMR experiments (COSY, HSQC and HMBC) and comparison with data reported in the literature. Riguera ester reactions and optical rotation measurements established the compounds as racemates. The antiparasitic activity of the compounds were tested against three strains of Leishmania spp., Trypanosoma cruzi and Plasmodium falciparum. The results showed that 3-(3,7-dimethyl-2,6-octadienyl)-4-methoxy-benzoic acid exhibited potent and selective activity against L. braziliensis (IC(50) 6.5 microg/ml), higher that pentamidine used as control. Moreover, 3-[(2E,6E,10E)-11-carboxy-3,7,15-trimethyl- 2,6,10,14-hexadecatetraenyl)-4,5-dihydroxybenzoic acid and 4-hydroxy-3-(3-methyl-1-oxo-2-butenyl)-5-(3-methyl-2-butenyl)benzoic acid showed moderate antiplasmodial (IC(50) 3.2 microg/ml) and trypanocidal (16.5 microg/ml) activities, respectively.

  12. Supervision in Language Teaching: A Supervisor's and Three Trainee Teachers' Perspectives

    Science.gov (United States)

    Kahyalar, Eda; Yazici, lkay Çelik

    2016-01-01

    This article reports on the findings from a study which investigated supervision in language teaching from a supervisor's and her three trainee teachers' perspectives. The data in the study were from three sources: 1) audio recordings of the supervisor's feedback sessions with each trainee teacher, 2) audio recording of an interview between the…

  13. Supervisor's Perceptions of the Work Attitudes of Two Groups of Employees

    Science.gov (United States)

    Brauchle, Paul E.; Azam, Md. Shafiqul

    2003-01-01

    This study investigates whether the type of job (i.e., information job versus noninformation job) had an effect on employee work attitudes as rated by their supervisors. In this study, the Occupational Work Ethic Inventory (OWEI), a self-reporting type instrument, was used to record supervisors' responses on the work attitudes of information and…

  14. Training Process Cycles for Special Education Teachers and University Supervisors: A Turkish Context

    Science.gov (United States)

    Vuran, Sezgin; Ergenekon, Yasemin

    2014-01-01

    In special education teacher training programs, the teaching practicum's role is both wide and extensive. Since, during this process, providing qualitative and satisfactory consulting services to supervisors is crucial, it is very important that university supervisors be experienced and have obtained proficiency in the field of consultation.…

  15. Mutual assumptions and facts about nondisclosure among clinical supervisors and students in group supervision

    DEFF Research Database (Denmark)

    Nielsen, Geir Høstmark; Skjerve, Jan; Jacobsen, Claus Haugaard;

    2009-01-01

    In the two preceding papers of this issue of Nordic Psychology the authors report findings from a study of nondisclosure among student therapists and clinical supervisors. The findings were reported separately for each group. In this article, the two sets of findings are held together and compared......, so as to draw a picture of mutual assumptions and facts about nondisclosure among students and supervisors....

  16. Supervisor Perspective on the Process and Outcome of Giving Easy, Difficult, or No Feedback to Supervisees

    Science.gov (United States)

    Hoffman, Mary Ann; Hill, Clara E.; Holmes, Stacey E.; Freitas, Gary F.

    2005-01-01

    Fifteen counseling center supervisors were interviewed about 3 instances related to important feedback with an intern supervisee: in which the feedback was given easily, in which it was given reluctantly or with difficulty, and another in which it was not given. Supervisors indicated that easy feedback was most often about clinical problems, was…

  17. 25 CFR 47.5 - What is the school supervisor responsible for?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the school supervisor responsible for? 47.5 Section 47.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.5 What is the school supervisor responsible for?...

  18. PhD students’ expectations from their supervisors: A qualitative content analysis

    Directory of Open Access Journals (Sweden)

    SH Rimaz

    2015-03-01

    Full Text Available Introduction: Quality of research in PhD programs increases if supervisors become aware of students' expectations from them. This qualitative study aimed to explore expectations of PhD students from their supervisors was done.   Methods: This qualitative content analysis study was conducted on 22 graduated PhD students of Iran University of Medical Sciences, in 2014. The samples were purposefully selected and interviewed. All interviews were recorded and transcribed verbatim.   Results: After analyzing and coding data, it was found that PhD students have four main expectations from their supervisors. These expectations consist of scientific support including help with selection of subject, preparation and registration of proposal, data collection and support for writing and examination of the thesis. Developing scientific skills and help with preparing manuscripts were other expectations. Emotional-social support with five categories including relationship between supervisor-student, general expectations of supervisor, supervisor personality characteristics, needed emotional skills and social activities related to thesis and finally providing adequate resources including financial support and access to facilities inside and outside the university were among the other expectations.   Conclusion: PhD students need to scientific, emotional, social and material supports from their supervisors in the process of performing thesis. These expectations should be told to supervisors.

  19. Communication Competence, Leadership Behaviors, and Employee Outcomes in Supervisor-Employee Relationships

    Science.gov (United States)

    Mikkelson, Alan C.; York, Joy A.; Arritola, Joshua

    2015-01-01

    Supervisor communication competence and leadership style were used to predict specific employee outcomes. In the study, 276 participants working in various industries completed measures of communication competence and leadership styles about their direct supervisor along with measures of their job satisfaction, motivation, and organizational…

  20. Supervisee Incompatibility and Its Influence on Triadic Supervision: An Examination of Doctoral Student Supervisors' Perspectives

    Science.gov (United States)

    Hein, Serge F.; Lawson, Gerard; Rodriguez, Christopher P.

    2011-01-01

    A qualitative study was conducted to explore supervisors' experiences of supervisee incompatibility in triadic supervision. In-depth interviews were completed with 9 doctoral student supervisors in a counselor education program, and a whole-text analysis generated 3 categories. Supervisee incompatibility took a wide variety of forms and negatively…

  1. Views of Educational Supervisors Concerning the Feasibility of Educational Supervision Regulation

    Science.gov (United States)

    Akbasli, Sait; Ozbas, Mehmet

    2012-01-01

    The main purpose of this study is to determine the level in which educational supervisors who carry out the regulations concerning the feasibility conditions of educational supervision regulation views arise. The research was carried out in 2010 to 2011 academic year; the research population included 3150 educational supervisors and the research…

  2. Pre-Service Teachers' Beliefs about the Roles of Thesis Supervisors: A Case Study

    Science.gov (United States)

    Tapia Carlín, Rebeca Elena

    2013-01-01

    Trainee beliefs about the roles of thesis supervisors can exert an important influence on timely and successful completion of theses. This research article explores pre-service teacher beliefs about the roles of thesis supervisors through the analysis of their learning diaries. The aim of this study is to identify ways to improve supervisory…

  3. Curricular Goals and Personal Goals in Master's Thesis Projects: Dutch Student-Supervisor Dyads

    Science.gov (United States)

    de Kleijn, Renske A. M.; Meijer, Paulien C.; Brekelmans, Mieke; Pilot, Albert

    2013-01-01

    To be effective, feedback should be goal-related. In order to better understand goal-related feedback in Master's thesis projects, the present study explores the goals of supervisors and students in supervision dyads and similarities and differences within and between these dyads. Twelve supervisors and students were interviewed, and their goals…

  4. Individual "and" Triadic "and" Group: Supervisee and Supervisor Perceptions of Each Modality

    Science.gov (United States)

    Borders, L. DiAnne; Welfare, Laura E.; Greason, Paige B.; Paladino, Derrick A.; Mobley, A. Keith; Villalba, Jose A.; Wester, Kelly L.

    2012-01-01

    In this consensual qualitative research study, the authors explored supervisors' (n= 11) and their supervisees' (n= 31) perceptions of individual, triadic, and group supervision sessions during practicum. Data from supervisor individual interviews and supervisee focus-group interviews revealed several themes regarding the advantages and…

  5. Supervisor-Subordinate Age Dissimilarity and Performance Ratings: The Buffering Effects of Supervisory Relationship and Practice

    Science.gov (United States)

    Van der Heijden, Beatrice I. J. M.; Scholarios, Dora; Van der Schoot, Esther; Jedrzejowicz, Piotr; Bozionelos, Nikos; Epitropaki, Olga; Knauth, Peter; Marzec, Izabela; Mikkelsen, Aslaug; Van der Heijde, Claudia

    2010-01-01

    Using 394 pairs of employees and their immediate supervisors working in the Information and Communication Technology (ICT) sector in three northern European countries, this study examined the effect of workplace moderators on the link between relational demography and supervisor ratings of performance. Directional age differences between superior…

  6. Supervisor-subordinate age dissimilarity and performance ratings: the buffering effects of supervisory relationship and practice

    NARCIS (Netherlands)

    van der Heijden, B.I.J.M.; Scholarios, D.; van der Schoot, E.; Jedrzejowicz, P.; Bozionelos, N.; Epitropaki, O.; Knauth, P.; Marzec, I.; Mikkelsen, A.; van der Heijde, C.

    2010-01-01

    Using 394 pairs of employees and their immediate supervisors working in the Information and Communication Technology (ICT) sector in three northern European countries, this study examined the effect of workplace moderators on the link between relational demography and supervisor ratings of performan

  7. Perceptions of Graduates and Their Supervisors Related to the Air and Space Basic Course

    Science.gov (United States)

    Kraska, Marie F.; Bentley, Terry R.

    2004-01-01

    The Air and Space Basic Course (ASBC) solicits feedback from field commanders and supervisors; however, it does not currently use any type of graduate or supervisor evaluation system. The ASBC has no mechanism in place to guarantee feedback about how the course has or has not prepared its graduates to function as military leaders. Consequently,…

  8. A patient safety curriculum for medical residents based on the perspectives of residents and supervisors.

    NARCIS (Netherlands)

    Jansma, J.D.; Wagner, C.; Bijnen, A.B.

    2011-01-01

    Objectives: To develop a patient safety course for medical residents based on the views of medical residents and their supervisors. Methods: In 2007, questionnaires were distributed to investigate residents' and supervisors' perspectives on the current patient safety performance and educational need

  9. Student and Supervisor Perceptions of the Ethical Environment of Retail Merchandising Internship Sites.

    Science.gov (United States)

    Paulins, V. Ann

    2001-01-01

    Senior retail merchandising students (n=37) and their internship supervisors (n=25) were surveyed about ethical practices. Perceptions of ethics did not vary by internship location. Supervisors perceived their organizations to be more ethical than students did on two of five questions. (Contains 15 references.) (SK)

  10. 30 CFR 250.174 - When may the Regional Supervisor grant or direct an SOP?

    Science.gov (United States)

    2010-07-01

    ... direct an SOP? 250.174 Section 250.174 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... § 250.174 When may the Regional Supervisor grant or direct an SOP? The Regional Supervisor may grant or direct an SOP when the suspension is in the national interest, and it is necessary because the...

  11. Communication Competence, Leadership Behaviors, and Employee Outcomes in Supervisor-Employee Relationships

    Science.gov (United States)

    Mikkelson, Alan C.; York, Joy A.; Arritola, Joshua

    2015-01-01

    Supervisor communication competence and leadership style were used to predict specific employee outcomes. In the study, 276 participants working in various industries completed measures of communication competence and leadership styles about their direct supervisor along with measures of their job satisfaction, motivation, and organizational…

  12. The Implications of Cognitive Style for the Management of Student-Supervisor Relationships.

    Science.gov (United States)

    Armstrong, Steven; Allinson, Christopher W.; Hayes, John

    1997-01-01

    Describes an innovative program of supervision that uses qualitative methods to match a student with a thesis supervisor. The program uses cognitive styles analysis to match students and supervisors whereas the supervision process focuses more on the student's research than the particular subject matter. Includes tabular and statistical data. (MJP)

  13. Industrial Safety. MAS-123. Waste Isolation Division (WID). Management and Supervisor Training (MAST) Program.

    Science.gov (United States)

    Westinghouse Electric Corp., Carlsbad, NM.

    This learning module, which is part of a management and supervisor training program for managers and supervisors employed at the Department of Energy's Waste Isolation Division, is designed to prepare trainees to promote and monitor the industrial safety program at their plant. The following topics are covered in the module's individual sections:…

  14. Supervisors and Teamwork. Tierra de Oportunidad Module 24. LAES: Latino Adult Education Services Project.

    Science.gov (United States)

    Kissam, Ed; Dorsey, Holda

    This module, which may be used as the basis for a workshop or as a special topic unit in adult basic education or English-as-a-Second-Language (ESL) courses, discusses supervisors and teamwork. It is designed to teach about differences between supervision in different kinds of workplaces; getting along and ahead with mainstream supervisors; and…

  15. Student and Supervisor Perceptions of the Ethical Environment of Retail Merchandising Internship Sites.

    Science.gov (United States)

    Paulins, V. Ann

    2001-01-01

    Senior retail merchandising students (n=37) and their internship supervisors (n=25) were surveyed about ethical practices. Perceptions of ethics did not vary by internship location. Supervisors perceived their organizations to be more ethical than students did on two of five questions. (Contains 15 references.) (SK)

  16. Organizational work factors among workers and supervisors in export processing zones which support global markets.

    Science.gov (United States)

    Del Prado-Lu, Jinky Leilanie

    2008-10-01

    This is an investigation of the interaction between organizational and management factors at work for both workers and supervisors in the manufacturing sector. Survey was done in a sample consisted of 23 establishments, 630 workers, and 47 supervisors, meanwhile 10 focus group discussions (FGDs) for workers, and 5 FGDs for supervisors. Workers and supervisors alike reported illnesses and job dissatisfaction. Survey showed that the most prevalent issues among workers were: the need to upgrade skills (76.3%), pressured in doing work (60.5%), fast paced work (60.5%), repetitive work (63%), and that work is both physically and mentally tiring (59.7%). On the other hand, supervisors described their work as challenging and stimulating (66%), needed regular upgrading of skills (46.8%), and needed literacy on information technology (31.9%). Focus group discussions showed that workers and supervisors were confronted with stress, fast-paced work, the need to upgrade skills due to accommodation of information technology into the work production, fatigue, re-engineering and downsizing by management, low job control and difficult worker-supervisor relationship. This study was able to show that health of workers and supervisors were affected by both organizational and management factors at work.

  17. A New Supervisor with a New Agenda: A Principal Ponders Political Options and Risks

    Science.gov (United States)

    Derrington, Mary Lynne; Larsen, Donald

    2015-01-01

    A tenured respected principal learns that supervisory relationships with staff are only one side of the leadership coin. The other side turns up when a new assistant superintendent is assigned as his supervisor. Problems are imminent when the supervisor seems ready to usurp the principal's traditional decision-making authority. The principal, as…

  18. Ethics in the Supervisory Relationship: Supervisors' and Doctoral Students' Dilemmas in the Natural and Behavioural Sciences

    Science.gov (United States)

    Löfström, Erika; Pyhältö, Kirsi

    2017-01-01

    This study explored the perceptions of ethical issues in supervision among doctoral students and supervisors. The nature of ethical issues identified by doctoral students (n = 28) and their supervisors (n = 14) is explored and the degree of fit and misfit between their perceptions in two cases representing the natural and behavioural sciences is…

  19. Associations of Low-Income Working Mothers' Daily Interactions with Supervisors and Mother-Child Interactions

    Science.gov (United States)

    Gassman-Pines, Anna

    2011-01-01

    This study investigated associations of low-income working mothers' daily interactions with supervisors and their interactions with children. Sixty-one mothers of preschool-aged children were asked to report on their interactions with their supervisors at work and their interactions with children for 2 weeks (N = 520 workdays). Results show…

  20. Utilization of Online Training for On-Site Clinical Supervisors: One University's Approach.

    Science.gov (United States)

    Getz, Hildy G.; Schnurman-Crook, Abrina

    2001-01-01

    The need to train on-site clinical supervisors often clashes with the practicality of time constraints of a variety of counseling professionals, as well as a significant geographical separation. This article is an overview of how one university developed online training to provide supervision training to clinical supervisors unable to attend live…

  1. Supervisors' perceptions of organizational policies are associated with their likelihood to accommodate back-injured workers.

    Science.gov (United States)

    McGuire, Connor; Kristman, Vicki L; Shaw, William S; Loisel, Patrick; Reguly, Paula; Williams-Whitt, Kelly; Soklaridis, Sophie

    2017-02-01

    Background Low back pain (LBP) is a major concern among North American workplaces and little is known regarding a supervisor's decision to support job accommodation for workers with LBP. The extent to which supervisors are included in a company's effort to institute disability management policies and practices and workplace safety climate are two factors that may influence a supervisor's decision to accommodate workers with LBP. Objective Determine the association between supervisors' perceptions of disability management policies, corporate safety culture and their likelihood of supporting job accommodations for workers with LBP. Methods We conducted a cross-sectional study of supervisors (N=796) recruited from a non-random, convenience sample of 19 Canadian and US employers. The outcome was supervisors' likeliness to support job accommodation and the exposure was global work safety culture and disability management policies and practices. A multivariable generalized linear modelling strategy was used and final models for each exposure were obtained after assessing potential effect modifiers and confounders. Results In the study, 796 eligible supervisors from 19 employers participated. Disability management policies and practices were positively associated with supervisors' likeliness to accommodate (β=0.19; 95% CI: 0.13; 0.24) while no significant association was found between corporate safety culture (β= -0.084; 95% CI: -0.19; 0.027) and supervisors' likeliness to accommodate. Conclusions Employers should ensure that proactive disability management policies and practices are clearly communicated to supervisors in order to improve job modification and return to work efforts. Implications for Rehabilitation Low back pain (LBP) is a major workplace concern and little is known regarding what factors are associated with a supervisor's likelihood to support job accommodation for workers with LBP. The objective of this article was to determine the association

  2. Establishing supervisor-students’ relationships through mutual expectation: A study from supervisors’ point of view

    Science.gov (United States)

    Masek, Alias

    2017-08-01

    The literature suggests that failure to establish a good relationship in communicating expectations of research supervision is one of the factors contributing to the slow pace of research progress. Moreover, it is not fully understood how students and a supervisor ‘pre-define’ their styles and communicate their expectations through a successful relationship. As a result, the students might lose motivation to do their research during the study period and are not able to complete their research on time. This will subsequently entail an extension of the study period. Without a good relationship between students and the supervisor, miscommunication occurs, leading to mismatched expectations from both parties. This research attempts to explore the establishment of a good supervisor-students’ relationship from supervisor point of views, so that supervision expectations can be clearly delivered and effectively communicated; guidelines will be drawn up for forging the supervisor-students’ relationship basing on mutual expectations of both parties.

  3. Accounting for subordinate perceptions of supervisor power: an identity-dependence model.

    Science.gov (United States)

    Farmer, Steven M; Aguinis, Herman

    2005-11-01

    The authors present a model that explains how subordinates perceive the power of their supervisors and the causal mechanisms by which these perceptions translate into subordinate outcomes. Drawing on identity and resource-dependence theories, the authors propose that supervisors have power over their subordinates when they control resources needed for the subordinates' enactment and maintenance of current and desired identities. The joint effect of perceptions of supervisor power and supervisor intentions to provide such resources leads to 4 conditions ranging from highly functional to highly dysfunctional: confirmation, hope, apathy, and progressive withdrawal. Each of these conditions is associated with specific outcomes such as the quality of the supervisor-subordinate relationship, turnover, and changes in the type and centrality of various subordinate identities. ((c) 2005 APA, all rights reserved).

  4. Developing skilled doctor–patient communication in the workplace: a qualitative study of the experiences of trainees and clinical supervisors

    NARCIS (Netherlands)

    E. Giroldi (Esther); I.K. Veldhuijzen (Irene); Geelen, K. (Kristel); J. Muris; F. Bareman (Frits); H.J. Bueving (Herman); T. van der Weijden (Trudy); C.P.M. van der Vleuten (Cees)

    2017-01-01

    textabstractTo inform the development of recommendations to facilitate learning of skilled doctor–patient communication in the workplace, this qualitative study explores experiences of trainees and supervisors regarding how trainees learn communication and how supervisors support trainees’ learning

  5. The supervisor in the project-organized group work should participate in developing the students' project competencies

    DEFF Research Database (Denmark)

    Hansen, Søren

    2004-01-01

    The article demonstrates how the supervisor can facilitate development of competencies as an implicit part of supervising study projects.......The article demonstrates how the supervisor can facilitate development of competencies as an implicit part of supervising study projects....

  6. ATLAS EventIndex Data Collection Supervisor and Web Interface

    CERN Document Server

    Garcia Montoro, Carlos; The ATLAS collaboration; Sanchez, Javier

    2016-01-01

    The EventIndex project consists in the development and deployment of a complete catalogue of events for the ATLAS experiment [1][2] at the LHC accelerator at CERN. In 2015 the ATLAS experiment has produced 12 billion real events in 1 million files, and 5 billion simulated events in 8 million files. The ATLAS EventIndex is running in production since mid-2015, reliably collecting information worldwide about all produced events and storing them in a central Hadoop infrastructure. A subset of this information is copied to an Oracle relational database. This paper presents two components of the ATLAS EventIndex [3]: its data collection supervisor and its web interface partner.

  7. Enhancing the skills of PhD supervisors facing internationalization

    DEFF Research Database (Denmark)

    Bøgelund, Pia

    2013-01-01

    This research started out due to some institutional changes at a department at Aalborg University as regards supervision of PhD students. For various reasons the department suddenly got a large intake of PhD students in 2008, many of which came with an international background. After a period...... of time staff members of the department began to look very frustrated. Not only did they feel burdened with the large intake, they also struggled with the task of facilitating the transition of international students to become independent scholars. The situation led to the creation of a more general...... interview study within the faculty, and an inquiry into the field of cross-cultural supervision with the purpose of enhancing the skills of PhD supervisors. As is often the case with cross-cultural exchange and inquiry, the study ended up by being just as informative on the supervision cultures and settings...

  8. How personality traits affect clinician-supervisors' work engagement and subsequently their teaching performance in residency training.

    Science.gov (United States)

    Scheepers, Renée A; Arah, Onyebuchi A; Heineman, Maas Jan; Lombarts, Kiki M J M H

    2016-11-01

    Clinician-supervisors often work simultaneously as doctors and teachers. Supervisors who are more engaged for their teacher work are evaluated as better supervisors. Work engagement is affected by the work environment, yet the role of supervisors' personality traits is unclear. This study examined (i) the impact of supervisors' personality traits on work engagement in their doctors' and teachers' roles and (ii) how work engagement in both roles affects their teaching performance. Residents evaluated supervisors' teaching performance, using the validated System for Evaluation of Teaching Qualities. Supervisors' reported work engagement in doctor and teacher roles separately using the validated Utrecht Work Engagement Scale. Supervisors' personality traits were measured using the Big Five Inventory's five factor model covering conscientiousness, agreeableness, extraversion, emotional stability and openness. Overall, 549 (68%) residents and 636 (78%) supervisors participated. Conscientiousness, extraversion and agreeableness were positively associated with supervisors' engagement in their teacher work, which was subsequently positively associated with teaching performance. Conscientious, extraverted, and agreeable supervisors showed more engagement with their teacher work, which made them more likely to deliver adequate residency training. In addition to optimizing the work environment, faculty development and career planning could be tailor-made to fit supervisors' personality traits.

  9. The Supervisor Training Curriculum: Evidence-Based Ways to Promote Work Quality and Enjoyment among Support Staff (Trainee Guide)

    Science.gov (United States)

    American Association on Intellectual and Developmental Disabilities, 2011

    2011-01-01

    "The Trainee Guide for the Supervisor Training Curriculum" summarizes key points in the Curriculum and is meant as a note taking and reference tool. The Supervisor Training Curriculum instructs supervisors on ways in which they can direct and motivate staff working with people with intellectual disabilities. Based on three decades of applied…

  10. Pushing too Little, Praising too Much? Intercultural Misunderstandings between a Chinese Doctoral Student and a Dutch Supervisor

    NARCIS (Netherlands)

    Hu, Yanjuan; van Veen, Klaas; Corda, Alessandra

    2016-01-01

    To understand the challenges and their causes in interactions between Western supervisors and international doctoral students, we conducted a self-study of our experiences as a Chinese international student and her Dutch supervisor during her doctoral research project. We found the supervisor and th

  11. Pushing too Little, Praising too Much? Intercultural Misunderstandings between a Chinese Doctoral Student and a Dutch Supervisor

    NARCIS (Netherlands)

    Hu, Yanjuan; van Veen, Klaas; Corda, Alessandra

    2016-01-01

    To understand the challenges and their causes in interactions between Western supervisors and international doctoral students, we conducted a self-study of our experiences as a Chinese international student and her Dutch supervisor during her doctoral research project. We found the supervisor and th

  12. Evaluation of hand for terry towels based on PhabrOmeter%基于PhabrOmeter的毛巾织物手感风格评价

    Institute of Scientific and Technical Information of China (English)

    屠吉利; 刘今强

    2013-01-01

    In order to explore the applied value of PhabrOmeter3 fabric evaluation system in softening effect evaluation of terry towels,PhabrOmeter3 was used to measure the hand values of terry towels and the results were compared with those obtained from subjective evaluations.The terry towels,which were used for subjective and objective evaluations,were treated by dipping with 3 kinds of different softeners of two concentrations,respectively,and after conditioning they were subjected to subjective and objective evaluations.The results showed that PhabrOmeter not only provides a convenient and efficient way to test fabric hand,including stiffness,softness,smoothness,draping value and relative hand value,but also reveals the effect of different softeners on fabric hand,and the difference between different finish concentrations.If sequencing the samples by softness degree,the order was consistent with that by the subjective evaluation.%为探求织物手感性能测量仪器PhabrOmeter3在毛巾类织物柔软整理效果评价中的应用价值,客观测试了毛巾类织物的手感风格值,并与主观手感评价结果进行对比.实验选取3种不同的柔软剂以2种浓度浸渍处理毛巾织物,调湿后用于主客观风格测试.结果表明,PhabrOmeter评价系统不仅可以方便快捷地测试织物的手感风格特征,包括硬挺度、光滑度、柔软度、悬垂系数及相对手感值,而且可清楚地揭示不同柔软剂对织物手感的影响程度以及不同浓度整理效果间的区别,其中,若将试样以柔软程度进行排序,其结果与主观柔软评价的顺序一致.

  13. Science supervisors' conceptions of biology and the field of science: A qualitative study

    Science.gov (United States)

    Young, Jean Radcliff

    1999-12-01

    This study examined the nature, source and formation of science supervisors' cognitive frameworks for biology and for the field of science and the impact of these frameworks on their work in school divisions. The design for this qualitative study was an emergent case study using ethnographic methods. The purposeful sample consisted of five science supervisors selected from different school divisions in three geographic regions of a middle-Atlantic state. Each participant had a background in biology, classroom teaching and full-time supervisory experience. To collect data for this study, an open-ended questionnaire was used to gain an understanding of the nature of the supervisors' conceptions of biology and for the field of science. Two semi-structured interviews, each lasting 1--2 hours in length, were designed to explore the source and formation of the supervisors' conceptual frameworks, and the impact of these frameworks on their work in school divisions. Data were inductively analyzed using a constant comparative approach. The major findings of this study were: (1) All of the supervisors in this study were remarkably cognizant of possessing a framework for biology and for the field of science. (2) The supervisors' frameworks were well-formed, relatively highly complex and showed a variety of organizational patterns. (3) All of the supervisors' diagrams showed evidence of coherent, integrated themes with emphasis on the importance of connections and interrelationships. (4) The supervisors were able to readily articulate sound rationales for construction of their diagrams. (5) Instead of seeing biology as an isolated discipline, the supervisors view biology in the context of science. Overall, the supervisors no longer see their frameworks as biology-content related, but as science-related. (6) Major influences on the source and formation of the supervisors' conceptual frameworks were a result of selected work-related experiences. (7) The supervisors' conceptual

  14. Morfoanatomia dos órgãos vegetativos de Piper hispidum Sw. (Piperaceae Morphology and anatomy of the vegetative organs of Piper hispidum Sw. (Piperaceae

    Directory of Open Access Journals (Sweden)

    Adriana L.M. Albiero

    2006-09-01

    Full Text Available O presente trabalho teve por objetivo o estudo morfoanatômico dos órgãos vegetativos de Piper hispidum, visando a estabelecer características marcantes para a sua identificação e auxiliar estudos taxonômicos e farmacobotânicos. O material vegetal fresco e fixado foi estudado segundo as técnicas usuais de corte e coloração, incluindo análise em MEV. Piper hispidum é um arbusto com caule cilíndrico, nodoso, verde claro, com folhas alternas, ovadas, de cor verde-escura na face adaxial e verde claro na abaxial. Dentre as características anatômicas importantes para sua identificação destacam-se: parênquima cortical da raiz apresentando grupos de esclereídes. Córtex caulinar com faixas descontínuas de colênquima do tipo angular e tecido vascular organizado em dois círculos descontínuos de feixes colaterais. A folha é dorsiventral, hipoestomática, com estômatos tetracíticos. Hipoderme adaxial descontínua e abaxial frouxa com número variável de camadas; tricomas tectores e glandulares ocorrem nas duas faces. Epiderme uniestratificada e idioblastos oleíferos ocorrem em todos os órgãos.The morphology and anatomy of the vegetative organs of Piper hispidum are described, detaching remarkable strutural aspects and contributing to taxonomical and pharmacobotanical studies. The material was studied according to the usual techniques, including SEM (Scaning Eletron Microscopy. Piper hispidum is a shrub with cylindrical and green stem, which has alternate leaves. The main anatomical characteristics that can be used in its identification are: root with sclereids on cortical parenchyma, stem cortex with discontinuous strands of angular collenchyma, and vascular tissue constituted by two discontinous circles of collateral vascular bundles. The leaf is dorsiventral and hypostomatic with tetracytic stomata. The hypodermis is discontinuous in adaxial face, loose in abaxial one and presents a variable number of layers. Uniseriate

  15. Perbedaan Daya Hambat Ekstrak Daun Sirih Hijau ( Piper betle L. dan Daun Sirih Merah ( Piper crocatum Ruiz & Pav terhadap Pertumbuhan Escherichia coli

    Directory of Open Access Journals (Sweden)

    Tristika Aulia Syahrinastiti

    2015-05-01

    Full Text Available AbstrakSirih hijau (Piper betle L. dan sirih merah (Piper crocatum Ruiz & Pav dipercaya memiliki khasiat mencegah penyakit infeksi saluran kemih yang disebabkan oleh Escherichia coli. Tujuan penelitian ini adalah untuk menjelaskan perbedaan daya hambat ekstrak daun sirih hijaudan daun sirih merah terhadap pertumbuhan Escherichia coli. Jenis penelitian ini adalah eksperimental dengan desain post test only control group. Penelitian dilakukan di laboratorium mikrobiologi Fakultas Kedokteran Universitas Andalas. Hasil penelitian adalah: 1. Efek daya hambat ekstrak daun sirih merah pada konsentrasi 2,5%, 5%, 7,5%, dan 10%, yaitu 0,6cm, 1,1cm, 1,2cm, dan 1,2cm; 2. Ekstrak daun sirih hijau tidak memiliki efek daya hambat pada konsentrasi 2,5%, 5%, 7,5%, dan 10%. Kesimpulan eksperimen ini adalah ekstrak daun sirih merah memiliki efek daya hambat lebih baik daripada ekstrak daun sirih hijau.Kata kunci: ekstrak daun sirih hijau, ekstrak daun sirih merah, escherichia coli, daerah bebas hambat AbstractGreen betel (Piper betle L. and red betel (Piper crocatum Ruiz & Pav are trusted of possessing an efficacy of preventing urinary tract infection caused by Eschericia coli. The objective of this study was to explain the difference of inhibition zones between the green betel and the red betel towards the growth of Eschericia coli. The type of this research was experimental study with post test only control group design. This research was carried out in Microbiology Laboratory, Faculty of Medicine Andalas University.The results of this research were: 1.The inhibition zones of red betel extract in concentration of 2.5%, 5%, 7.5%, and 10% were 0.6 cm, 1.1 cm, 1.2 cm, and 1.2 cm; 2. The extract of green betel had none of inhibition zones in concentration of of 2.5%, 5%, 7.5%, and 10%. In conclusion, the red betel extract has better inhibition zones than the green betel extrac.Keywords: green betel extract, red betel extract, eschericia coli, inhibition zone

  16. BIOEFFICACY OF PIPER RIBESIOIDES (PIPERACEAE) EXTRACTS AGAINST NILAPARVATA LUGENS STAL. (HOMOPTERA: DELPHACIDAE).

    Science.gov (United States)

    Phankaen, Y; Pluempanupat, W; Mourad, A K; Bullangpoti, V

    2014-01-01

    The extracts of stem and seeds of Piper ribesioides (Piperaceae) were prepared in hexane, dichloromethane, ethyl acetate and ethanol and evaluated for their efficacy against 3-day-old adult brown plant hoppers, Nilaparvata lugens Stal under laboratory conditions. The treatment was given topically and results suggest the dose dependent response related to exposure time. The ethyl acetate extract was the best with an LC50 = 738 ppm-, 24 h post-treatment. There was substantial increase in activity (LC50 = 27.298 ppm) with the increase in duration of exposure. This trend was observed in all treatments that suggests the potential of Piper ribesioides as an insecticide for N. lugens as an alternative control.

  17. Cytotoxic, mutagenic and genotoxic evaluation of crude extracts and fractions from Piper jericoense with trypanocidal action.

    Science.gov (United States)

    Hamedt, A L; Ortiz, I C; García-Huertas, P A; Sáenz, J; de Araujo, A Caldeira; De Mattos, J C P; Rodríguez-Gazquez, M A; Triana-Chávez, O

    2014-03-01

    The current Chagas disease treatment is based on two drugs, nifurtimox and benznidazole, which is considered unsatisfactory, not only because of the narrow therapeutic range but also because of the associated toxicity. Natural products are considered an important source of biologically active compounds against various infectious organisms. Numerous Piper species are used in traditional medicine to treat parasitic diseases. In this paper, we study the activity of extracts and fractions obtained from Piper jericoense plant against epimastigote, trypomastigote and amastigote forms of Trypanosoma cruzi. In addition, we evaluated the cytotoxic, mutagenic and genotoxic activities of the F4 fraction obtained from one of the more promising extracts. We obtained four extracts, one of which presented low toxicity and high trypanocidal activity. This extract was separated into eight fractions, and the F4 fraction presented better results than the other extracts and had a higher selectivity index than the reference drug, benznidazole. This fraction was not cytotoxic, mutagenic or genotoxic.

  18. PRENYLATED BENZOIC ACID DERIVATIVES FROM PIPER SPECIES AS SOURCE OF ANTI-INFECTIVE AGENTS

    Directory of Open Access Journals (Sweden)

    Ibrahim Malami

    2012-06-01

    Full Text Available A number of prenylated benzoic acids derivatives with interesting biological activities have been previously isolated and characterized from different species of piperaceae family. Several Piper species contained structurally similar compounds with diverse biological activities such as anti-bacterial, anti-fungal, insecticidal as well as anti-parasitic all of which produces compounds that can be classified as prenylated benzoic acid derivatives. Piper sp has proven to serve as a source of potential anti-infective agents by developing a biosynthetic route to the synthesis of prenylated benzoic acids derivative natural products as their chemical defense system. Despite the frequent isolation of these interesting compounds with strong biological activity, yet none have been taking into consideration for development into therapeutic agents.

  19. Insecticidal activity against Spodoptera frugiperda (Lepidoptera: Noctuidae) of metabolites isolated from the aerial part of Piper septuplinervium (Miq.) c. dc. and inflorescences of Piper subtomentosum Trel. and Yunck. (Piperaceae); Actividad insecticida sobre Spodoptera frugiperda (Lepidoptera: Noctuidae) de los compuestos aislados de la parte aerea de Piper septuplinervium (Miq.) c. dc. y las inflorescencias de Piper subtomentosum Trel. and Yunck. (Piperaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Murillo, Monica Constanza Avila; Suarez, Luis Enrique Cuca, E-mail: mcavilam@unal.edu.co [Laboratorio de Productos Naturales Vegetales, Departamento de Quimica, Facultad de Ciencias, Universidad Nacional de Colombia, Bogota (Colombia); Salamanca, Jairo Alonso Ceron [Laboratorio de Biopesticidas, Instituto de Biotecnologia, Universidad Nacional de Colombia, Bogota (Colombia)

    2014-05-15

    The bioassay-guided purification of ethanolic extracts from inflorescences of Piper subtomentosum Trel. and Yunck and aerial part of Piper septuplinervium (Miq. ) C. DC. led to isolation of five flavonoids, uvangoletin (1), galangin (2), chrysin (5), 5-hydroxy-4',7-dimethoxy-flavone (6), pinostrobin (7); one amide, N-p-coumaroil-tyramine (4); one acylglycerol, monopalmitin (3); one derivative of acid, protocatechuic acid (8); and glycosydated sterol, daucosterol (9). Their structures were elucidated on the basis of spectroscopy and spectrometry data and by comparison with data reported in the literature. The isolated compounds were tested against Spodoptera frugiperda. The results showed galangin and protocatechuic acid to be the most active (LC{sub 50} 13.63 and 17.16 ppm, respectively). (author)

  20. Influence of temperature on symptom expression, detection of host factors in virus infected Piper nigrum L.

    Science.gov (United States)

    Umadevi, P; Bhat, A I; Krishnamurthy, K S; Anandaraj, M

    2016-05-01

    Expression of symptoms in black pepper plants (Piper nigrum) infected with Piper yellow mottle virus (PYMoV) vary depending on the season, being high during summer months. Here, we explored the influence of temperature on symptom expression in PYMoV infected P. nigrum. Our controlled environment study revealed increase in virus titer, total proteins, IAA and reducing sugars when exposed to temperature stress. There was change in the 2-D separated protein before and after exposure. The 2-D proteomics LC-MS identified host and viral proteins suggesting virus-host interaction during symptom expression. The analysis as well as detection of host biochemical compounds may help in understanding the detailed mechanisms underlying the viral replication and damage to the crop, and thereby plan management strategies.

  1. Protocols for Improvement of Black Pepper (Piper nigrum L.) Utilizing Biotechnological Tools.

    Science.gov (United States)

    Nirmal Babu, K; Divakaran, Minoo; Yamuna, G; Ravindran, P N; Peter, K V

    2016-01-01

    Black pepper, Piper nigrum L., the "King of spices" is the most widely used spice growing in the South-Western region of India. The humid tropical evergreen forest bordering the Malabar Coast (Western Ghats is one of the hot spot areas of plant bio-diversity on earth) is its center of origin and diversity. However, the crop faces constraints like rampant fungal and viral diseases, lack of disease free planting material, hence biotechnological tools can be utilized to address these problems and strides have been made successfully. The standardization of micropropagation, somatic embryogenesis, in vitro conservation, protoplast isolation, and genetic transformation protocols are described here. The protocols could be utilized to achieve similar goals in the related species of Piper too.

  2. Melanogenesis stimulation in murine B16 melanoma cells by Kava (Piper methysticum) rhizome extract and kavalactones.

    Science.gov (United States)

    Matsuda, Hideaki; Hirata, Noriko; Kawaguchi, Yoshiko; Naruto, Shunsuke; Takata, Takanobu; Oyama, Masayoshi; Iinuma, Munekazu; Kubo, Michinori

    2006-04-01

    Melanogenesis stimulation activity of aqueous ethanolic extracts obtained from several different parts of five Piper species, namely Piper longum, P. kadsura, P. methysticum, P. betle, and P. cubeba, were examined by using cultured murine B16 melanoma cells. Among them, the extract of P. methysticum rhizome (Kava) showed potent stimulatory effect on melanogenesis as well as P. nigrum leaf extract. Activity-guided fractionation of Kava extract led to the isolation of two active kavalactones, yangonin (2) and 7,8-epoxyyangonin (5), along with three inactive kavalactones, 5,6-dehydrokawain (1), (+)-kawain (3) and (+)-methysticin (4), and a glucosylsterol, daucosterin (6). 7,8-Epoxyyangonin (5) showed a significant stimulatory effect on melanogenesis in B16 melanoma cells. Yangonin (2) exhibited a weak melanogenesis stimulation activity.

  3. Hydrolysis of methyl benzoate from Piper arboreum by Naupactus bipes beetle

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, Clecio S.; Kato, Massuo J. [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Quimica]. E-mail: majokato@iq.usp.br

    2009-07-01

    A new natural product was isolated from Piper arboreum (Piperaceae) leaves, the methyl 3-geranyl-4-hydroxybenzoate (1). The metabolism of P. arboreum leaves by Naupactus bipes beetle (Germar, 1824 - Coleoptera: Curculionidae) led to the hydrolysis of 1 to 3-geranyl-4-hydroxybenzoic acid (2). The structures of both compounds were determined based on spectroscopic analysis ({sup 1}H and {sup 13}C NMR, MS, and IR). (author)

  4. Views of Astronaut (Col.) Joe Engle and son Jon with L-5 Piper Cub

    Science.gov (United States)

    1981-01-01

    Views of Astronaut (Col.) Joe Engle and son Jon with L-5 Piper Cub at Clover Airport. Photos includes Jon Engle sitting on side door frame working on portion of wing. Joe Engle is behind him working on a wing strut (34329); Joe Engle works on tightening bolt (34330); Jon Engle works on portion of wing which connects to the cockpit. Joe Engle works on connecting strut to wing (34331).

  5. Age-dependent changes from allylphenol to prenylated benzoic acid production in Piper gaudichaudianum Kunth.

    Science.gov (United States)

    Gaia, Anderson M; Yamaguchi, Lydia F; Jeffrey, Christopher S; Kato, Massuo J

    2014-10-01

    HPLC-DAD and principal component analysis (PCA) of the (1)H NMR spectrum of crude plant extracts showed high chemical variability among seedlings and adult organs of Piper gaudichaudianum. While gaudichaudianic acid was the major compound in the adult leaves, apiole and dillapiole were the major compounds in their seedling leaves. By the 15th month of seedling growth, the levels of apiole and dillapiole decreased and gaudichaudianic acid appeared along with two compounds, biosynthetically related to gaudichaudianic acid.

  6. Influence of phytochemicals in piper betle linn leaf extract on wound healing

    OpenAIRE

    Lien, Le Thi; Tho, Nguyen Thi; Ha, Do Minh; Hang, Pham Luong; Nghia, Phan Tuan; Thang, Nguyen Dinh

    2015-01-01

    Background Wound healing has being extensively investigated over the world. Healing impairment is caused by many reasons including increasing of free-radicals-mediated damage, delaying in granulation tissue formation, reducing in angiogenesis and decreasing in collagen reorganization. These facts consequently lead to chronic wound healing. Piper betle Linn (Betle) leaves have been folklore used as an ingredient of drugs for cutaneous wound treatment. However, the effect of betle leaf on wound...

  7. Scanning Electron Microscopic study of Piper betle L. leaves extract effect against Streptococcus mutans ATCC 25175

    Directory of Open Access Journals (Sweden)

    Zubaidah Haji Abdul Rahim

    2011-04-01

    Full Text Available INTRODUCTION: Previous studies have shown that Piper betle L. leaves extract inhibits the adherence of Streptococcus mutans to glass surface, suggesting its potential role in controlling dental plaque development. OBJECTIVES: In this study, the effect of the Piper betle L. extract towards S. mutans (with/without sucrose using scanning electron microscopy (SEM and on partially purifed cell-associated glucosyltransferase activity were determined. MATERIAL AND METHODS: S. mutans were allowed to adhere to glass beads suspended in 6 different Brain Heart Infusion broths [without sucrose; with sucrose; without sucrose containing the extract (2 mg mL-1 and 4 mg mL-1; with sucrose containing the extract (2 mg mL-1 and 4 mg mL-1]. Positive control was 0.12% chlorhexidine. The glass beads were later processed for SEM viewing. Cell surface area and appearance and, cell population of S. mutans adhering to the glass beads were determined upon viewing using the SEM. The glucosyltransferase activity (with/without extract was also determined. One- and two-way ANOVA were used accordingly. RESULTS: It was found that sucrose increased adherence and cell surface area of S. mutans (p<0.001. S. mutans adhering to 100 µm² glass surfaces (with/without sucrose exhibited reduced cell surface area, fuffy extracellular appearance and cell population in the presence of the Piper betle L. leaves extract. It was also found that the extract inhibited glucosyltransferase activity and its inhibition at 2.5 mg mL-1 corresponded to that of 0.12% chlorhexidine. At 4 mg mL-1 of the extract, the glucosyltransferase activity was undetectable and despite that, bacterial cells still demonstrated adherence capacity. CONCLUSION: The SEM analysis confrmed the inhibitory effects of the Piper betle L. leaves extract towards cell adherence, cell growth and extracellular polysaccharide formation of S. mutans visually. In bacterial cell adherence, other factors besides glucosyltransferase are

  8. Isolation and Characterization of Antidermatophytic Bioactive Molecules from Piper longum L. Leaves

    OpenAIRE

    Das, Jayshree; D.K.Jha; Policegoudra, R. S.; Mazumder, Afjal Hussain; Das, Mrinmoy; Chattopadhyay, P.; Singh, L.

    2012-01-01

    Piper longum L. (Piperaceae) commonly known as “long pepper” is a well known medicinal plant in ayurveda. Different parts of this plant, such as root, seed, fruit, whole plant etc. are used traditionally in various ailments. Here we have investigated the antidermatophytic activity of sequentially extracted petroleum ether, chloroform, methanol and water extracts from P. longum leaf against Trichophytonmentagrophytes, T. rubrum, T. tonsurans, Microsporum fulvum and M. gypseum. Better activity ...

  9. Views of Astronaut (Col.) Joe Engle and son Jon with L-5 Piper Cub

    Science.gov (United States)

    1981-01-01

    Views of Astronaut (Col.) Joe Engle and son Jon with L-5 Piper Cub at Clover Airport. Photos includes Jon Engle sitting on side door frame working on portion of wing. Joe Engle is behind him working on a wing strut (34329); Joe Engle works on tightening bolt (34330); Jon Engle works on portion of wing which connects to the cockpit. Joe Engle works on connecting strut to wing (34331).

  10. Phosphate-solubilizing microbes and their occurrence in the rhizospheres of Piper betel in Karnataka, India

    OpenAIRE

    TALLAPRAGADA, Padmavathi; SESHACHALA, Usha

    2012-01-01

    Low phosphate solubility is one of the most important factors limiting the plant growth in Indian soils. Many microorganisms can enhance phosphate solubility, but little is known about the magnitude of their phosphorus-solubilizing ability. The native populations of phosphate-solubilizing bacteria and fungi were studied in different rhizospheric soil samples obtained from betel vine plants (Piper betel L.) in order to compare the results. The present study focuses on the phosphate-solubilizin...

  11. Synchronous EMG activity in the Piper frequency band reveals the corticospinal demand of walking tasks

    OpenAIRE

    Clark, David J.; Kautz, Steven A.; Bauer, Andrew R.; Chen, Yen-Ting; Evangelos A Christou

    2013-01-01

    Evidence indicates that the frequency-domain characteristics of surface electromyogram (EMG) signals are modulated according to the contributing sources of neural drive. Modulation of inter-muscular EMG synchrony within the Piper frequency band (30–60Hz) during movement tasks has been linked to drive from the corticospinal tract. However, it is not known whether EMG synchrony is sufficiently sensitive to detect task-dependent differences in the corticospinal contribution to leg muscle activat...

  12. Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo.

    Science.gov (United States)

    Ghoshal, S; Prasad, B N; Lakshmi, V

    1996-03-01

    The fruits of Piper longum used in traditional remedies against intestinal distress have been tested for their efficacy against experimental caecal amoebiasis of rats. The ethanolic extract, hexane fraction, n-butanol soluble fraction exerted in vitro amoebicidal action at 1000 micrograms/mL and the chloroform fraction at 500 micrograms/mL. The ethanolic extract and piperine, a pure compound, from this plant material cured 90% and 40% of rats with caecal amoebiasis, respectively.

  13. Preventive potentials of piperlongumine and a Piper longum extract against stress responses and pain

    OpenAIRE

    Yadav, Vaishali; Chatterjee, Shyam Sunder; Majeed, Muhammed; Kumar, Vikas

    2015-01-01

    Aim To compare stress resistance increasing and analgesic activities of piperlongumine and a methanolic Piper longum fruit extract (PLE). Methods Efficacies of a single and repeated daily oral doses (1–256 mg/kg/day) of PLE, piperlongumine, and 50 mg/kg/day doxycycline against foot shock stress triggered alteration in body weights and core temperatures, and of their 11 daily doses on antidepressants like activity in tail suspension test and on pentobarbital induced sedation in male mice were ...

  14. In vitro cytotoxic and in silico activity of piperine isolated from Piper nigrum fruits Linn

    OpenAIRE

    2015-01-01

    Background Piper nigrum [Piperaceae], commonly known as black pepper is used as medicine fairly throughout the greater part of India and as a spice globally. Purpose To isolate piperine and evaluate in vitro cytotoxic [antiproliferative] activity and in silico method. Methods Piperine was isolated from the fruits of P.nigrum. Piperine was characterized by UV,IR, 1H-NMR, 13C-NMR and Mass spectrum. Standardization of piperine was done also by HPTLC fingerprinting. In vitro cytotoxic activity wa...

  15. The role of supervisor emotional support on individual job satisfaction: A multilevel analysis.

    Science.gov (United States)

    Pohl, Sabine; Galletta, Maura

    2017-02-01

    Supervisor emotional support is a strong determinant of job satisfaction. There is no study examining the effect of supervisor emotional support at the group level on job satisfaction. Multilevel statistical techniques can help disentangle the effects of subjective assessments from those of group factors. The study's aim was to examine the moderating role of supervisor emotional support (group-level variable) on the relationship between work engagement and job satisfaction (individual-level variables). A cross-sectional study was performed in 39units from three Belgian hospitals. A total of 323 nurses completed a self-reported questionnaire. We carried out a multilevel analysis by using Hierarchical Linear Modeling. The results showed that the cross-level interaction was significant. Hence, at individual-level, the nurses with high levels of work engagement showed high levels of job satisfaction and this relationship was stronger when supervisor emotional support at group-level was high. Contextual differences among groups had an impact on the form of the work engagement-job satisfaction relationship. This relationship between work engagement and job satisfaction is an individual and group level phenomenon. Ways to enhance emotional supervisor support include training supervisors in providing support and enhancing communication between nurses and supervisors. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Attitudes towards disability management: A survey of employees returning to work and their supervisors.

    Science.gov (United States)

    Busse, Jason W; Dolinschi, Roman; Clarke, Andrew; Scott, Liz; Hogg-Johnson, Sheilah; Amick, Benjamin C; Rivilis, Irina; Cole, Donald

    2011-01-01

    Return to work after a leave on disability is a common phenomenon, but little is known about the attitudes of employees or their supervisors towards the disability management process. We report on employee and supervisor feedback from one disability management experience. 389 consecutive employees from the Ontario offices of a single private Canadian insurance company returning to work from short-term disability, and their supervisors. We surveyed employees and their supervisors about their experience with, and attitudes towards, the disability management process. Of those surveyed, 88 employees and 75 supervisors provided data (response rates of 22.6% and 19.3% respectively). The majority of respondents (79.1% of employees and supervisors) endorsed positive attitudes towards their disability management experience. More than 25% of employees disagreed with the following three items: case managers contributed to recovery, case managers removed barriers to recovery, and sufficient support was provided in the return to work process. More than 25% of employees and managers reported that a commitment to modify an unhelpful work situation was not followed through. The majority of participating employees returning to work from short-term disability, and their supervisors, reported a high level of satisfaction with the disability management process. Areas that may benefit from attention include some aspects of case manager-employee interaction and ensuring that support during the return to work process is provided, including modification to work situations when appropriate.

  17. Moving empirically supported practices to addiction treatment programs: recruiting supervisors to help in technology transfer.

    Science.gov (United States)

    Amodeo, Maryann; Storti, Susan A; Larson, Mary Jo

    2010-05-01

    Federal and state funding agencies are encouraging or mandating the use of empirically supported treatments in addiction programs, yet many programs have not moved in this direction (Forman, Bovasso, and Woody, 2001 ; Roman and Johnson, 2002 ; Willenbring et al., 2004 ). To improve the skills of counselors in community addiction programs, the authors developed an innovative Web-based course on Cognitive Behavioral Therapy (CBT), a widely accepted empirically-supported practice (ESP) for addiction. Federal funding supports this Web course and a randomized controlled trial to evaluate its effectiveness. Since supervisors often play a pivotal role in helping clinicians transfer learned skills from training courses to the workplace, the authors recruited supervisor-counselor teams, engaging 54 supervisors and 120 counselors. Lessons learned focus on supervisor recruitment and involvement, supervisors' perceptions of CBT, their own CBT skills and their roles in the study, and implications for technology transfer for the addiction field as a whole. Recruiting supervisors proved difficult because programs lacked clinical supervisors. Recruiting counselors was also difficult because programs were concerned about loss of third-party reimbursement. Across the addiction field, technology transfer will be severely hampered unless such infrastructure problems can be solved. Areas for further investigation are identified.

  18. Radio-sensitization by Piper longumine of human breast adenoma MDA-MB-231 cells in vitro.

    Science.gov (United States)

    Yao, Jian-Xin; Yao, Zhi-Feng; Li, Zhan-Feng; Liu, Yong-Biao

    2014-01-01

    The current study investigated the effects of Piper longumine on radio-sensitization of human breast cancer MDA-MB-231 cells and underlying mechanisms. Human breast cancer MDA-MB-231 cells were cultured in vitro and those in logarithmic growth phase were selected for experiments divided into four groups: control, X-ray exposed, Piper longumine, and Piper longumine combined with X-rays. Conogenic assays were performed to determine the radio-sensitizing effects. Cell survival curves were fitted by single-hit multi-target model and then the survival fraction (SF), average lethal dose (D0), quasi-threshold dose (Dq) and sensitive enhancement ratio (SER) were calculated. Cell apoptosis was analyzed by flow cytometry (FCM).Western blot assays were employed for expression of apoptosis-related proteins (Bc1-2 and Bax) after treatment with Piper longumine and/or X-ray radiation. The intracellular reactive oxygen species (ROS) level was detected by FCM with a DCFH-DA probe. The cloning formation capacity was decreased in the group of piperlongumine plus radiation, which displayed the values of SF2, D0, Dq significantly lower than those of radiation alone group and the sensitive enhancement ratio (SER) of D0 was1.22 and 1.29, respectively. The cell apoptosis rate was increased by the combination treatment of Piper longumine and radiation. Piper longumine increased the radiation-induced intracellular levels of ROS. Compared with the control group and individual group, the combination group demonstrated significantly decreased expression of Bcl-2 with increased Bax. Piper longumine at a non-cytotoxic concentration can enhance the radio-sensitivity of MDA- MB-231cells, which may be related to its regulation of apoptosis-related protein expression and the increase of intracellular ROS level, thus increasing radiation-induced apoptosis.

  19. How do social networks and faculty development courses affect clinical supervisors' adoption of a medical education innovation? An exploratory study.

    Science.gov (United States)

    Jippes, Erik; Steinert, Yvonne; Pols, Jan; Achterkamp, Marjolein C; van Engelen, Jo M L; Brand, Paul L P

    2013-03-01

    To examine the impact of social networks and a two-day faculty development course on clinical supervisors' adoption of an educational innovation. During 2007-2010, 571 residents and 613 clinical supervisors in four specialties in the Netherlands were invited to complete a Web-based questionnaire. Residents rated their clinical supervisors' adoption of an educational innovation, the use of structured and constructive (S&C) feedback. Clinical supervisors self-assessed their adoption of this innovation and rated their communication intensity with other clinical supervisors in their department. For each supervisor, a centrality score was calculated, representing the extent to which the supervisor was connected to departmental colleagues. The authors analyzed the effects of supervisor centrality and participation in a two-day Teach-the-Teacher course on the degree of innovation adoption using hierarchical linear modeling, adjusting for age, gender, and attitude toward the S&C feedback innovation. Respondents included 370 (60%) supervisors and 357 (63%) residents. Although Teach-the-Teacher course participation (n=172; 46.5%) was significantly related to supervisors' self-assessments of adoption (P=.001), it had no effect on residents' assessments of supervisors' adoption (P=.371). Supervisor centrality was significantly related to innovation adoption in both residents' assessments (P=.023) and supervisors' self-assessments (P=.024). A clinical supervisor's social network may be as important as faculty development course participation in determining whether the supervisor adopts an educational innovation. Faculty development initiatives should use faculty members' social networks to improve the adoption of educational innovations and help build and maintain communities of practice.

  20. 用多臂小样织机开发毛巾织物%Development of Terry Towel by Dobby Sample Weaving Loom

    Institute of Scientific and Technical Information of China (English)

    刘蓉; 杨建忠

    2012-01-01

    It transformed the dobby sample loom of Y2005 to meet the experiment need for developing new towel fabric, then by changing the organization, warp and weft density ratio, yarn count, textile raw material and pile loop height, it developed 2 kinds of terry towel, and tested and evaluated the fabric feeling by semantic evaluation method.%通过对Y2005型多臂小样织机的改造以满足开发新型毛巾面料的实验需要,变化组织、经纬密比、纱线支数、织物原料及毛圈高度等参数试织了两种毛巾织物,并用语意评定法测评了织物手感风格。

  1. Monitoring the Excavation Damaged Zone in Opalinus clay by three dimensional reconstruction of the electrical resistivity in the Mont Terri gallery G-04

    Science.gov (United States)

    Lesparre, N.; Adler, A.; Nicollin, F.; Gibert, D.; Nussbaum, C.

    2012-04-01

    The characteristics of opalinus clay have been studied in the last years for its capacity to retain radionuclide transport as a low permeable rock. This formation presents thereby suitable properties for hosting repository sites of radioactive waste. The Mont Terri underground rock laboratory (Switzerland) has been excavated in opalinus clay layer in order to develop experiences improving the knowledge on the physico-chemical properties of the rock. The study of electrical properties furnishes information on the rock structure, its anisotropy and the changes of these properties with time (Nicollin et al., 2010 ; Thovert et al., 2011). Here the three dimensional reconstruction of the electrical resistivity aims at monitoring the temporal evolution of the excavation damaged zone. Three rings of electrodes have been set-up around the gallery and voltage is measured between two electrodes while a current is injected between two others (Gibert et al., 2006). Measurements have been achieved from July 2004 until April 2008 before, during and after the excavation of the gallery 04. In this study we develop a computational approach to reconstruct three dimensional images of the resistivity in the vicinity of the electrodes. A finite element model is used to represent the complex geometry of the gallery. The measurements inferred from a given resistivity distribution are estimated using the software EIDORS (Adler and Lionheart, 2006), this constitutes the forward problem. The reconstruction of the media resistivity is then implemented by fitting the estimated to the measured data, via the resolution of an inverse problem. The parameters of this inverse problem are defined by mapping the forward problem elements into a coarser mesh. This allows to reduce drastically the number of unknowns and so increases the robustness of the inversion. The inversion is executed with the conjugate gradient method regularised by an analysis of the Jacobian singular values. The results show an

  2. Discontinuity networks in mud stones: an apparent contradiction for boom clay at Mol, opalinus clay at Mont Terri, Callovo-Oxfordian silty clay at Bure

    Energy Technology Data Exchange (ETDEWEB)

    Arnould, M. [Centre de Geologie de l' Ingenieur, 75 - Paris (France); Mazurek, M. [Bern Univ., Rock-Water Interaction, Institute of Geological Sciences (Switzerland); Vandenberghe, N. [Katholieke Universiteit (KU), Lab. voor stratigrafie Leuven (Belgium)

    2005-07-01

    The Rupelian Boom Clay at Mol, Belgium, the lower Aalenian Opalinus Clay at Mont Terri Switzerland and the Callovo-Oxfordian silty clay at Bure, France, are currently studied in the framework of deep geological radioactive waste confinement. These three mud-stones are calcareous to variable degrees. They vary from plastic clay at Mol to hard rock at Bure. All three have similar mineralogical constituents, especially with regards to the clay minerals and include mixed layers of illite and montmorillonite. Remarkably, in outcrop sections of massive clay formations and mud-stone in general, it is very common to observe a network of discontinuities resembling the jointing in hard rock. As such jointing clearly would influence underground works it is imperative to examine whether or not the three mud-rock formations under discussion have such a discontinuity network in all their mass. (authors)

  3. Chemical Constituents from Piper wallichii%石南藤化学成分研究

    Institute of Scientific and Technical Information of China (English)

    赵云; 阮金兰

    2006-01-01

    Aim To investigate the chemical constituents of Piper wallichii. Methods Five compounds were isolated by silica gel column chromatography and Sephadex LH-20 gel column chromatography, and the structures of compounds were identified by spectral analysis. Result Five compounds were identified as piperlonguminine (trans, trans) (1), 4-hydroxy-3,5-dimethoxy-benzoic acid (2), galgravin (3), β-sitosterol (4), and daucosterol (5). Conclusion Five compounds were isolated from Piper wallichii for the first time, and compounds 1-3 were isolated from this genus for the first time.%目的对石南藤Piper wallichii化学成分进行研究.方法应用硅胶、葡聚糖凝胶等色谱技术分离纯化,应用波谱技术确定化合物的结构.结果从石南藤中分离得到了5个化合物,分别为piperlonguminine (trans,trans) (1),4-羟基-3,5-二甲氧基-苯甲酸 (2),galgravin (3),β-谷甾醇 (4)以及胡萝卜苷 (5).结论五个化合物均为首次从石南藤中得到,化合物1~3为首次从胡椒属中得到.

  4. Chemical and biological analyses of the essential oils and main constituents of Piper species.

    Science.gov (United States)

    Moura do Carmo, Dominique F; Amaral, Ana Cláudia Fernandes; Machado, Gérzia M C; Leon, Leonor Laura; Silva, Jefferson Rocha de Andrade

    2012-02-13

    The essential oils obtained from leaves of Piper duckei and Piper demeraranum by hydrodistillation were analyzed by gas chromatography-mass spectrometry. The main constituents found in P. demeraranum oil were limonene (19.3%) and β-elemene (33.1%) and in P. duckei oil the major components found were germacrene D (14.7%) and trans-caryophyllene (27.1%). P. demeraranum and P. duckei oils exhibited biological activity, with IC(50) values between 15 to 76 μg mL(-1) against two Leishmania species, P. duckei oil being the most active. The cytotoxicity of the essential oils on mice peritoneal macrophage cells was insignificant, compared with the toxicity of pentamidine. The main mono- and sesquiterpene, limonene (IC(50) = 278 μM) and caryophyllene (IC(50) = 96 μM), were tested against the strains of Leishmania amazonensis, and the IC(50) values of these compounds were lower than those found for the essential oils of the Piper species. The HET-CAM test was used to evaluate the irritation potential of these oils as topical products, showing that these oils can be used as auxiliary medication in cases of cutaneous leishmaniasis, with less side effects and lower costs.

  5. Antidiabetic activities of aqueous and ethanolic extracts of Piper betle leaves in rats.

    Science.gov (United States)

    Arambewela, L S R; Arawwawala, L D A M; Ratnasooriya, W D

    2005-11-14

    Leaves of Piper betle (Piperaceae) possess several bioactivities and are used in traditional medicinal systems. However, its antidiabetic activity has not been scientifically investigated so far. The aim of this study therefore, was to investigate the antidiabetic activity of Piper betle leaves. This was tested in normoglycaemic and strepozotocin (STZ)-induced diabetic rats using oral administration of hot water extract (HWE) and cold ethanolic extract (CEE). In normoglycaemic rats, both HWE and CEE significantly lowered the blood glucose level in a dose-dependent manner. In glucose tolerance test, both extracts markedly reduced the external glucose load. The antidiabetic activity of HWE is comparable to that of CEE. Moreover, HWE failed to inhibit the glucose absorption from the small intestine of rats. Both extracts were found to be non-toxic and well tolerated after following chronic oral administration (no overt signs of toxicity, hepatotoxicity or renotoxicity). However, the weight of the spleen had increased in treated groups possibly indicating lymphoproliferative activity. It is concluded that HWE and CEE of Piper betle leaves possess safe and strong antidiabetic activity.

  6. Chemical Composition and Acetylcholinesterase Inhibitory Activity of Essential Oils from Piper Species.

    Science.gov (United States)

    Xiang, Cai-Peng; Han, Jia-Xin; Li, Xing-Cong; Li, Yun-Hui; Zhang, Yi; Chen, Lin; Qu, Yan; Hao, Chao-Yun; Li, Hai-Zhou; Yang, Chong-Ren; Zhao, San-Jun; Xu, Min

    2017-05-10

    The essential oils (EOs) derived from aromatic plants such as Piper species are considered to play a role in alleviating neuronal ailments that are associated with inhibition of acetylcholinesterase (AChE). The chemical compositions of 23 EOs prepared from 16 Piper spp. were analyzed by both gas chromatography with a flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). A total of 76 compounds were identified in the EOs from the leaves and stems of 19 samples, while 30 compounds were detected in the EOs from the fruits of four samples. Sesquiterpenes and phenylpropanoids were found to be rich in these EOs, of which asaricin, caryophyllene, caryophyllene oxide, isospathulenol, (+)-spathulenol, and β-bisabolene are the major constituents. The EOs from the leaves and stems of Piper austrosinense, P. puberulum, P. flaviflorum, P. betle, and P. hispidimervium showed strong AChE inhibitory activity with IC50 values in the range of 1.51 to 13.9 mg/mL. A thin-layer chromatography (TLC) bioautography assay was employed to identify active compound(s) in the most active EO from P. hispidimervium. The active compound was isolated and identified as asaricin, which gave an IC50 value of 0.44 ± 0.02 mg/mL against AChE, comparable to galantamine with an IC50 0.15 ± 0.01 mg/mL.

  7. Rapid green synthesis of silver nanoparticles and nanorods using Piper nigrum extract

    Energy Technology Data Exchange (ETDEWEB)

    Mohapatra, Bandita [Multifunctional Nanomaterials Laboratory, School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Dwarka, New Delhi 110078 (India); Kuriakose, Sini [Multifunctional Nanomaterials Laboratory, School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Dwarka, New Delhi 110078 (India); School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Dwarka, New Delhi 110078 (India); Mohapatra, Satyabrata, E-mail: smiuac@gmail.com [Multifunctional Nanomaterials Laboratory, School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Dwarka, New Delhi 110078 (India); School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Dwarka, New Delhi 110078 (India)

    2015-07-15

    Highlights: • Silver nanorods were synthesized by photoreduction using Piper nigrum extract. • The morphological and structural properties were studied by XRD and AFM. • Silver nanoparticles were formed at lower AgNO{sub 3} concentration. • Increase in AgNO{sub 3} concentration resulted in formation of silver nanorods. - Abstract: We report sun light driven rapid green synthesis of stable aqueous dispersions of silver nanoparticles and nanorods at room temperature using photoreduction of silver ions with Piper nigrum extract. Silver nanoparticles were formed within 3 min of sun light irradiation following addition of Piper nigrum extract to the AgNO{sub 3} solution. The effects of AgNO{sub 3} concentration and irradiation time on the formation and plasmonic properties of biosynthesized silver nanoparticles were studied using UV–visible absorption spectroscopy. The morphology and structure of silver nanoparticles were well characterized by atomic force microscopy (AFM) and X-ray diffraction (XRD). The size of Ag nanoparticles increased with increase in irradiation time, leading to the formation of anisotropic nanostructures. Increasing the AgNO{sub 3} concentration resulted in the formation of Ag nanorods. UV–visible absorption studies revealed the presence of surface plasmon resonance (SPR) peaks which red shift and broaden with increasing AgNO{sub 3} concentration. We have demonstrated a facile, energy efficient and rapid green synthetic route to synthesize stable aqueous dispersions of silver nanoparticles and nanorods.

  8. Chemical and Biological Analyses of the Essential Oils and Main Constituents of Piper Species

    Directory of Open Access Journals (Sweden)

    Leonor Laura Leon

    2012-02-01

    Full Text Available The essential oils obtained from leaves of Piper duckei and Piper demeraranum by hydrodistillation were analyzed by gas chromatography-mass spectrometry. The main constituents found in P. demeraranum oil were limonene (19.3% and β-elemene (33.1% and in P. duckei oil the major components found were germacrene D (14.7% and trans-caryophyllene (27.1%. P. demeraranum and P. duckei oils exhibited biological activity, with IC50 values between 15 to 76 μg mL−1 against two Leishmania species, P. duckei oil being the most active. The cytotoxicity of the essential oils on mice peritoneal macrophage cells was insignificant, compared with the toxicity of pentamidine. The main mono- and sesquiterpene, limonene (IC50 = 278 μM and caryophyllene (IC50 = 96 μM, were tested against the strains of Leishmania amazonensis, and the IC50 values of these compounds were lower than those found for the essential oils of the Piper species. The HET-CAM test was used to evaluate the irritation potential of these oils as topical products, showing that these oils can be used as auxiliary medication in cases of cutaneous leishmaniasis, with less side effects and lower costs.

  9. Factor analysis of the Revised Piper Fatigue Scale in a caregiver sample.

    Science.gov (United States)

    Clark, Patricia C; Ashford, Susan; Burt, Rachel; Aycock, Dawn M; Kimble, Laura P

    2006-01-01

    The Revised Piper Fatigue Scale (R-PFS) is an instrument designed to measure subjective fatigue that was developed in samples with physical illness. Its psychometric properties in nonclinical samples are unknown. The purpose of this study was to examine the psychometric properties of the R-PFS in a sample of caregivers of stroke survivors. The convenience sample of 132 caregivers was primarily women (74%), White (71%), college-educated (73%), and employed (52%), with a mean age of 56.7 years (SD = 13.71). Internal consistency reliabilities for the four R-PFS subscales and the total scale were excellent, ranging from .90 to .97. Principal axis factor analysis with oblique rotation was conducted to examine construct validity of the R-PFS. A three-factor solution explained 75.9% of the common variance. Two factors totally replicated the behavioral/severity and affective meaning subscales of the R-PFS. The third factor incorporated a combination of Piper's sensory and cognitive/mood subscales and appeared to summarize how fatigue makes the caregiver feel. The R-PFS demonstrated strong internal consistency reliability and construct validity in this sample. However, data suggest that caregivers may perceive certain feelings associated with fatigue as conceptually similar when these feelings are conceptually distinct in Piper's breast cancer sample. The study supports the need for psychometric evaluation of instruments developed in clinical populations prior to their use in nonclinical populations.

  10. Use of a Robotic Sampler (PIPER for Evaluation of Particulate Matter Exposure and Eczema in Preschoolers

    Directory of Open Access Journals (Sweden)

    Lokesh Shah

    2016-02-01

    Full Text Available While the association of eczema with asthma is well recognized, little research has focused on the potential role of inhalable exposures and eczema. While indoor air quality is important in the development of respiratory disease as children in the U.S. spend the majority of their time indoors, relatively little research has focused on correlated non-respiratory conditions. This study examined the relationship between particulate matter (PM exposures in preschool age children and major correlates of asthma, such as wheeze and eczema. Air sampling was carried out using a robotic (PIPER child-sampling surrogate. This study enrolled 128 participants, 57 male and 71 female children. Ages ranged from 3 to 58 months with the mean age of 29.3 months. A comparison of subjects with and without eczema showed a difference in the natural log (ln of PM collected from the PIPER air sampling (p = 0.049. PIPER’s sampling observed an association between the ln PM concentrations and eczema, but not an association with wheezing history in pre-school children. Our findings are consistent with the hypothesis of the role of the microenvironment in mediating atopic dermatitis, which is one of the predictors of persistent asthma. Our findings also support the use of PIPER in its ability to model and sample the microenvironment of young children.

  11. Mont Terri Project - Engineered barrier emplacement experiment in Opalinus Clay for the disposal of radioactive waste in underground repositories

    Energy Technology Data Exchange (ETDEWEB)

    Mayor, J. C. [Empresa Nacional de Residuos Radioactivos SA (ENRESA), Madrid (Spain); Garcia-Sineriz, J. [Asociacion para la Investigacion y Desarollo Industrial de los Recursos Naturales (AITEMIN), Madrid (Spain); Alonso, E. [Centre Internacional de Metodos Numerics en Ingenyeria (CIMNE), Barcelona (Spain); Alheid, H.-J. [Bundesanstalt fuer Geowissenschaften und Rohstoffe (BGR), Hannover (Germany); Bluemling, P. [National Cooperative for the Disposal of Radioactive Waste (Nagra), Wettingen (Switzerland)

    2007-07-01

    The Engineered Barrier (EB) experiment was a full-scale test for the demonstration, in a horizontal drift, of an emplacement technics of the clay barrier, using a granular bentonite material in the upper part of this barrier and bentonite blocks at the bottom. The test has been carried out in a 6 m long section of a niche excavated in Opalinus Clay of the Mont Terri underground laboratory. A steel dummy canister, with the same dimensions and weight as the real reference canisters, was placed on top of a bed of highly compacted bentonite blocks (in turn lying on a concrete bed), and the rest of the clay barrier volume was backfilled with a Granular Bentonite Material (GBM), made of very highly compacted pellets of different sizes. Hydro-mechanical instrumentation and an artificial hydration system (to accelerate the saturation of the clay barrier) were installed, and the test section sealed with a concrete plug. The evolution of the hydro-mechanical parameters along the hydration, both in the barrier and in the clayey rock formation, has been monitored during about 1.5 years, and modelled using the CODE-BRIGHT code. The EB experiment has proved that fully automated production of a Granular Bentonite Material (GBM) is possible and large quantities can be produced in due time in the required quality. Only minor modifications of existing production lines in industry for other applications were necessary to achieve this result. In the EB test section, a dry density of 1.36 g/cm{sup 3} of the emplaced GBM has been obtained. With this value it is estimated that the hydraulic conductivity of this material is lower than 5 x 10{sup -12} m/s and the swelling pressure is about 1.3 MPa. Even though the EB test section conditions are now not considered as representative of a true demonstration, it is deemed that the model emplacement testing results (dry density of about 1.40 g/cm{sup 3}) serve well to demonstrate the achievable densities expected in the real world setting. The

  12. Chemical composition of essential oils of Piper jacquemontianum and Piper variabile from Guatemala and bioactivity of the dichloromethane and methanol extracts

    Directory of Open Access Journals (Sweden)

    Sully M. Cruz

    2011-08-01

    Full Text Available The essential oils from two native species from Guatemala were studied for their chemical composition and the dichloromethane and methanol extracts for their biological activity. A GC-MS analysis of the essential oil from Piper jacquemontianum Kunth, Piperaceae, showed 34 constituents, consisting mainly of linalool (69.4%, while Piper variabile C. DC. essential oil had 36 constituents, camphor (28.4%, camphene (16.6% and limonene (13.9% being the major components. Dichloromethane extracts of both species were cytotoxic against MCF-7, H-460 and SF-268 cell lines (<7 µg/mL. Dichloromethane extract of P. jacquemontianum was slightly active against bacteria (0.5 mg/mL, was active against promastigotes of Leishmania (20.4-61.0 µg/mL, and epimastigotes of Trypanosoma cruzi (51.9 µg/mL. The methanol extract of P. variabile showed antimalarial activity against Plasmodium falciparum F32 (4.5 µg/mL, and the dichloromethane extract against Leishmania (55.8-76.3 µg/mL and T. cruzi (45.8 µg/mL. None of the extracts from the two species was active against Aedes aegypti larvae and Artemia salina nauplii.

  13. Anatomia comparada de folhas de pimenta longa (Piper hispidinervum C. DC. e pimenta de macaco (Piper aduncum L. cultivadas in vitro, ex vitro e in vivo

    Directory of Open Access Journals (Sweden)

    Simone Alencar Maciel

    2014-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2014v27n4p11 Piper hispidinervum e Piper aduncum apresentam compostos metabólitos secundários como safrol e dilapiol de interesse comercial em seus óleos essenciais. O trabalho teve como objetivo comparar aspectos anatômicos, relacionados a respostas fisiológicas das folhas de P. hispidinervum e P. aduncum propagadas in vitro, in vivo e durante a aclimatização. Secções paradérmicas e transversais da lâmina foliar do cultivo in vitro, ex vitro e in vivo, feitas à mão-livre foram realizadas para a medição das estruturas anatômicas em microscópio de luz. A espessura da epiderme e hipoderme de P. hispidinervum e P. aduncum sofrem alterações na transição de cultivo in vitro para o ex vitro. Os tecidos do mesofilo e a abertura do poro estomático de ambas as espécies são influenciados pelo ambiente in vitro. Diferentes ambientes de cultivo promovem a plasticidade das estruturas celulares da lâmina foliar e fundamentam o sucesso da micropropagação de ambas as espécies.

  14. Natural quartz TL property and similarity in Piper nigrum L; Propiedad TL de cuarzo natural y similitud en pimienta negra (Piper nigrum L.)

    Energy Technology Data Exchange (ETDEWEB)

    Guzman A, S.; Cruz Z, E.; Furetta, C. [Unidad de Irradiacion y Seguridad Radiologica, Instituto de Ciencias Nucleares, UNAM, Circuito Exterior, Ciudad Universitaria, 04510 Mexico D. F. (Mexico); Brown, F. [Departamento de Investigacion en Polimeros y Materiales, Universidad de Sonora, Apdo. Postal 130, 83000 Hermosillo, Sonora (Mexico); Barboza F, M. [Centro de Investigacion en Fisica, Universidad de Sonora, Apdo. Postal 5-088, 83190 Hermosillo, Sonora (Mexico)], e-mail: ecruz@nucleares.unam.mx

    2009-10-15

    Quartz is a mineral abundant in nature and can provide information thermoluminescent (TL), and also is located in the mineral fraction of some herbs and spices consumed. It is present the analysis of the TL properties of a sample of natural quartz rock and compared with those obtained from the fraction of Piper nigrum L. poly mineral when they were exposed to {sup 60}Co gamma radiation. The poly minerals of Piper nigrum L. were analyzed by X-ray diffraction, where the quartz was found as a major component. They separated in different particle sizes (10, 53, 74 and 149 {mu}m). The samples were irradiated at relatively low doses (1-500 Gy) and high (0.1-40 kGy) in order to determine the linearity of the TL emission as a function of the dose and the analysis of glow curves. Also there was the fading of the TL signal, the effect of ultra violet light. The reproducibility of the TL signal in the samples indicates that a smaller particle size gives better TL signal. (author)

  15. Piper sarmentosum increases nitric oxide production in oxidative stress: a study on human umbilical vein endothelial cells

    Directory of Open Access Journals (Sweden)

    Azizah Ugusman

    2010-01-01

    Full Text Available OBJECTIVE: Nitric oxide produced by endothelial nitric oxide synthase (eNOS possesses multiple anti-atherosclerotic properties. Hence, enhanced expression of eNOS and increased Nitric oxide levels may protect against the development of atherosclerosis. Piper sarmentosum is a tropical plant with antioxidant and anti-inflammatory activities. This study aimed to investigate the effects of Piper sarmentosum on the eNOS and Nitric oxide pathway in cultured human umbilical vein endothelial cells (HUVECs. METHODS: HUVECs were divided into four groups: control, treatment with 180 μM hydrogen peroxide (H2O2, treatment with 150 μg/mL aqueous extract of Piper sarmentosum, and concomitant treatment with aqueous extract of PS and H2O2 for 24 hours. Subsequently, HUVECs were harvested and eNOS mRNA expression was determined using qPCR. The eNOS protein level was measured using ELISA, and the eNOS activity and Nitric oxide level were determined by the Griess reaction. RESULTS: Human umbilical vein endothelial cells treated with aqueous extract of Piper sarmentosum showed a marked induction of Nitric oxide. Treatment with PS also resulted in increased eNOS mRNA expression, eNOS protein level and eNOS activity in HUVECs. CONCLUSION: Aqueous extract of Piper sarmentosum may improve endothelial function by promoting NO production in HUVECs.

  16. EFFECTS OF PIPER BETLE LEAVES (PAAN EXTRACT AS ANTI-DEPRESSANT AND ANTI-ANXIETY IN EXPERIMENTAL ANIMALS

    Directory of Open Access Journals (Sweden)

    DR. HITESH GULHANE

    2015-04-01

    Full Text Available Objectives: The present study was undertaken to determine the anti-depressant and anti-anxiety effects of hydroethanolic extract of Piper betle leaves commonly known as “paan”. Materials and Methods: Hydroethanolic extract of Piper betle leaves in the doses of 100,200 and 400 mg were administered orally for successive 14 days to young Swiss albino mice of either sex. The antidepressant activity was evaluated by forced swim test and tail suspension test. On the other hand anti-anxiety activity was evaluated by light/dark exploration test and elevated plus maze test. Imipramine 15 mg/kg was used as standard in anti-depressant models and diazepam 2 mg/kg was used as standard in anti-anxiety models. Results: Hydroethanolic extract of Piper betle leaves of doses 200 and 400 mg/kg showed significant activity as compared with control in reducing the immobility time in forced swim test and tail suspension test. On the other hand, gradual increasing dose of extract of Piper betle leaves also showed significant activity in improving anxiety of mice as compared with control in light/dark exploration and elevated plus maze test. Conclusion: Hydroethanolic extract of Piper betle leaves showed anti-depressant activity probably acts through the mechanism of blocking the uptake of dopamine, noradrenaline and serotonin through their respective transporters. On the other hand, anti-anxiety activity acts probably through GABA but the role is not established.

  17. Essential oils of leaves of Piper species display larvicidal activity against the dengue vector, Aedes aegypti (Diptera: Culicidae

    Directory of Open Access Journals (Sweden)

    HT. SANTANA

    2015-03-01

    Full Text Available The mosquito Aedes aegypti is the vector of the dengue virus, an endemic arbovirus from tropical and subtropical regions of the world. The increasing resistance of mosquitoes to commercial insecticides impairs regular control programs; therefore, chemical prospecting originating from the Amazonian flora is promising for potential new insecticides. Several Piper species are, notably, rich in phenylpropanoids and terpenoids, substances with proven insecticidal activity. The composition and the larvicidal activity of three Piper species against A. aegypti were evaluated. Essential oils were extracted by hydrodistillation in a modified Clevenger apparatus and analyzed by GC/MS. The major components found in Piper arboreum were germacrene D (31.83% and bicyclogermacrene (21.40%; in Piper marginatum: (E-methyl isoeugenol (27.08%, (E-anethole (23.98% and (Z-methyl isoeugenol (12.01%; and in Piper aduncum: (E-isocroweacin (29.52% and apiole (28.62% and elemicin (7.82%. Essential oils from the Piperaceae species studied resulted in Lethal Concentrations (LC50 of 34-55 ppm, while LC90 was higher than 100 ppm, except for P. marginatum (85 ppm.

  18. Directed seed dispersal of Piper by Carollia perspicillata and its effect on understory plant diversity and folivory.

    Science.gov (United States)

    Salazar, Diego; Kelm, Detlev H; Salazar, Diego

    2013-11-01

    Directed dispersal occurs when seeds are differentially deposited to sites where offspring survivorship is higher than at randomly chosen sites. Traditionally, characteristics of the dispersal target sites that could increase survivorship of the dispersed plants are thought to be intrinsic to the sites. If directed dispersal is constant over extended periods of time, however, it is likely that nonrandom patterns of dispersal could modify the ecological characteristics of the target site in ways that could increase survivorship and fitness of the dispersed plants. Here we report patterns of Piper diversity (richness, equitability, and similarity) and Piper folivory within plots near natural or artificial roosts of Carollia perspicillata vs. similar plots without bat roosts. Plots with bat roosts, both natural and artificial, had significantly higher Piper species diversity. Additionally, we found that plots with a higher Piper species diversity showed less specialist folivory, higher generalist folivory, and lower total herbivore leaf damage than plots with low Piper diversity. Finally, plots with bat roosts also showed less specialist folivory, lower generalist folivory, and lower total folivory when compared to plots without roosts. We propose that long-lasting nonrandom patterns of seed dispersal can change the local ecological characteristics of target sites via changes in plant diversity, and that these changes are likely to reduce the local rates of folivory and, therefore, increase seed and adult plant survivorship.

  19. Piper sarmentosum increases nitric oxide production in oxidative stress: a study on human umbilical vein endothelial cells.

    Science.gov (United States)

    Ugusman, Azizah; Zakaria, Zaiton; Hui, Chua Kien; Nordin, Nor Anita Megat Mohd

    2010-07-01

    Nitric oxide produced by endothelial nitric oxide synthase (eNOS) possesses multiple anti-atherosclerotic properties. Hence, enhanced expression of eNOS and increased Nitric oxide levels may protect against the development of atherosclerosis. Piper sarmentosum is a tropical plant with antioxidant and anti-inflammatory activities. This study aimed to investigate the effects of Piper sarmentosum on the eNOS and Nitric oxide pathway in cultured human umbilical vein endothelial cells (HUVECs). HUVECS WERE DIVIDED INTO FOUR GROUPS: control, treatment with 180 microM hydrogen peroxide (H(2)O(2)), treatment with 150 microg/mL aqueous extract of Piper sarmentosum, and concomitant treatment with aqueous extract of PS and H(2)O(2) for 24 hours. Subsequently, HUVECs were harvested and eNOS mRNA expression was determined using qPCR. The eNOS protein level was measured using ELISA, and the eNOS activity and Nitric oxide level were determined by the Griess reaction. Human umbilical vein endothelial cells treated with aqueous extract of Piper sarmentosum showed a marked induction of Nitric oxide. Treatment with PS also resulted in increased eNOS mRNA expression, eNOS protein level and eNOS activity in HUVECs. Aqueous extract of Piper sarmentosum may improve endothelial function by promoting NO production in HUVECs.

  20. Supervisor localization a top-down approach to distributed control of discrete-event systems

    CERN Document Server

    Cai, Kai

    2016-01-01

    This monograph presents a systematic top-down approach to distributed control synthesis of discrete-event systems (DES). The approach is called supervisor localization; its essence is the allocation of external supervisory control action to individual component agents as their internal control strategies. The procedure is: first synthesize a monolithic supervisor, to achieve globally optimal and nonblocking controlled behavior, then decompose the monolithic supervisor into local controllers, one for each agent. The collective behavior of the resulting local controllers is identical to that achieved by the monolithic supervisor. The basic localization theory is first presented in the Ramadge–Wonham language-based supervisory control framework, then demonstrated with distributed control examples of multi-robot formations, manufacturing systems, and distributed algorithms. An architectural approach is adopted to apply localization to large-scale DES; this yields a heterarchical localization procedure, which is...

  1. Leader-member exchange and affective organizational commitment: the contribution of supervisor's organizational embodiment.

    Science.gov (United States)

    Eisenberger, Robert; Karagonlar, Gokhan; Stinglhamber, Florence; Neves, Pedro; Becker, Thomas E; Gonzalez-Morales, M Gloria; Steiger-Mueller, Meta

    2010-11-01

    In order to account for wide variation in the relationship between leader-member exchange and employees' affective organizational commitment, we propose a concept termed supervisor's organizational embodiment (SOE), which involves the extent to which employees identify their supervisor with the organization. With samples of 251 social service employees in the United States (Study 1) and 346 employees in multiple Portuguese organizations (Study 2), we found that as SOE increased, the association between leader-member exchange and affective organizational commitment became greater. This interaction carried through to in-role and extra-role performance. With regard to antecedents, we found in Study 1 that supervisor's self-reported identification with the organization increased supervisor's expression of positive statements about the organization, which in turn increased subordinates' SOE.

  2. Report: EPA Managers Did Not Hold Supervisors and Project Officers Accountable for Grants Management

    Science.gov (United States)

    Report #2005-P-00027, September 27, 2005. Managers did not sufficiently hold supervisors and project officers accountable for grants management because there is no process to measure most grants management activity.

  3. How clinical supervisors develop trust in their trainees: a qualitative study.

    NARCIS (Netherlands)

    Hauer, K.E.; Oza, S.K.; Kogan, J.R.; Stankiewicz, C.A.; Stenfors-Hayes, T.; ten Cate, TJ; Batt, Joanne; O’Sullivan, P.S.

    2015-01-01

    Context Clinical supervisors oversee trainees’ performance while granting them increasing opportunities to work independently. Although the factors contributing to supervisors’ trust in their trainees to conduct clinical work have been identified, how the development of trust is shaped by these

  4. The Relationship of Interpersonal Attraction, Experience, and Supervisor's Level of Functioning in Dyadic Counseling Supervision

    Science.gov (United States)

    Sundblad, Lloyd M.; Feinberg, Lawrence B.

    1972-01-01

    Results revealed that interpersonal attraction differentially affects the three facilitative dimensions and that experience mediates attraction differentially depending on the type rather than the amount of experience the supervisor has had. (Author)

  5. Clinical supervision of psychotherapy: essential ethics issues for supervisors and supervisees.

    Science.gov (United States)

    Barnett, Jeffrey E; Molzon, Corey H

    2014-11-01

    Clinical supervision is an essential aspect of every mental health professional's training. The importance of ensuring that supervision is provided competently, ethically, and legally is explained. The elements of the ethical practice of supervision are described and explained. Specific issues addressed include informed consent and the supervision contract, supervisor and supervisee competence, attention to issues of diversity and multicultural competence, boundaries and multiple relationships in the supervision relationship, documentation and record keeping by both supervisor and supervisee, evaluation and feedback, self-care and the ongoing promotion of wellness, emergency coverage, and the ending of the supervision relationship. Additionally, the role of clinical supervisor as mentor, professional role model, and gatekeeper for the profession are discussed. Specific recommendations are provided for ethically and effectively conducting the supervision relationship and for addressing commonly arising dilemmas that supervisors and supervisees may confront.

  6. She Pushed Me, and I Flew: A Duoethnographical Story From Supervisors in Flight

    National Research Council Canada - National Science Library

    Jacquie Kidd; Mary Patricia Finlayson

    2015-01-01

    .... In this article we use a duoethnographical approach to explore the supervisor-doctoral student dynamic that occurred during the production of a creative thesis from within a science-focused faculty...

  7. A Multitrait Multimethod Comparison of Job Reinforcer Ratings of Supervisors and Supervisees

    Science.gov (United States)

    Tinsley, Howard E. A.; Weiss, David J.

    1971-01-01

    This data suggests that supervisors and supervisees generally perceive reinforcer characteristics similarly, although the two groups of raters tended to disagree on the extrinsic reinforcers and on the reinforcer characteristics of lower level occupations. (Author)

  8. Retention preferences and the relationship between total rewards, perceived organisational support and perceived supervisor support

    National Research Council Canada - National Science Library

    Wilmien Smit; Karel Stanz; Mark Bussin

    2015-01-01

    .... Total reward factors, perceived organisational support and perceived supervisor support are distinct but related concepts, all of which appear to influence an employee's decision to stay at an organisation...

  9. Family Supportive Supervisor Behaviors and Organizational Culture: Effects on Work Engagement and Performance.

    Science.gov (United States)

    Rofcanin, Yasin; Las Heras, Mireia; Bakker, Arnold B

    2016-04-21

    Informed by social information processing (SIP) theory, in this study, we assessed the associations among family supportive supervisor behaviors (FSSBs) as perceived by subordinates, subordinate work engagement, and supervisor-rated work performance. Moreover, we explored the role of family supportive organizational culture as a contextual variable influencing our proposed associations. Our findings using matched supervisor-subordinate data collected from a financial credit company in Mexico (654 subordinates; 134 supervisors) showed that FSSBs influenced work performance through subordinate work engagement. Moreover, the positive association between subordinates' perceptions of FSSBs and work engagement was moderated by family supportive organizational culture. Our results contribute to emerging theories on flexible work arrangements, particularly on family supportive work policies. Moreover, our findings carry practical implications for improving employee work engagement and work performance. (PsycINFO Database Record

  10. A Model of Supervisor Decision-Making in the Accommodation of Workers with Low Back Pain.

    Science.gov (United States)

    Williams-Whitt, Kelly; Kristman, Vicki; Shaw, William S; Soklaridis, Sophie; Reguly, Paula

    2016-09-01

    Purpose To explore supervisors' perspectives and decision-making processes in the accommodation of back injured workers. Methods Twenty-three semi-structured, in-depth interviews were conducted with supervisors from eleven Canadian organizations about their role in providing job accommodations. Supervisors were identified through an on-line survey and interviews were recorded, transcribed and entered into NVivo software. The initial analyses identified common units of meaning, which were used to develop a coding guide. Interviews were coded, and a model of supervisor decision-making was developed based on the themes, categories and connecting ideas identified in the data. Results The decision-making model includes a process element that is described as iterative "trial and error" decision-making. Medical restrictions are compared to job demands, employee abilities and available alternatives. A feasible modification is identified through brainstorming and then implemented by the supervisor. Resources used for brainstorming include information, supervisor experience and autonomy, and organizational supports. The model also incorporates the experience of accommodation as a job demand that causes strain for the supervisor. Accommodation demands affect the supervisor's attitude, brainstorming and monitoring effort, and communication with returning employees. Resources and demands have a combined effect on accommodation decision complexity, which in turn affects the quality of the accommodation option selected. If the employee is unable to complete the tasks or is reinjured during the accommodation, the decision cycle repeats. More frequent iteration through the trial and error process reduces the likelihood of return to work success. Conclusion A series of propositions is developed to illustrate the relationships among categories in the model. The model and propositions show: (a) the iterative, problem solving nature of the RTW process; (b) decision resources necessary

  11. A Training Intervention for Supervisors to Support a Work-Life Policy Implementation

    Directory of Open Access Journals (Sweden)

    Naima Laharnar

    2013-09-01

    Conclusion: CBT is an effective strategy to increase supervisors' knowledge and awareness to support policy implementation. The lack of supervisor training and knowledge of an important but complex employee benefit exposes a serious impediment to effective policy implementation and may lead to negative outcomes for the organization and the employee, supporting the Ryan-Kossek model. The results further demonstrate that long-time employees need supplementary training on complex workplace policies such as FMLA.

  12. Clinical teaching in restorative dentistry and the variation between students' and supervisors' perceptions of its effectiveness.

    LENUS (Irish Health Repository)

    Polyzois, I

    2010-05-01

    To investigate if there was an agreement between the students and supervisors on the quality of clinical teaching in Restorative Dentistry in the Dublin Dental School and Hospital and to identify differences on how effective clinical teaching is perceived between three academic years. In addition it aimed to identify the existence of any similarities between students\\' and supervisors\\' perceptions of specific teaching behaviours that are most and least helpful in learning.

  13. Genetic Counseling Supervisors' Self-Efficacy for Select Clinical Supervision Competencies.

    Science.gov (United States)

    Finley, Sabra Ledare; Veach, Pat McCarthy; MacFarlane, Ian M; LeRoy, Bonnie S; Callanan, Nancy

    2016-04-01

    Supervision is a primary instructional vehicle for genetic counseling student clinical training. Approximately two-thirds of genetic counselors report teaching and education roles, which include supervisory roles. Recently, Eubanks Higgins and colleagues published the first comprehensive list of empirically-derived genetic counseling supervisor competencies. Studies have yet to evaluate whether supervisors possess these competencies and whether their competencies differ as a function of experience. This study investigated three research questions: (1) What are genetic counselor supervisors' perceptions of their capabilities (self-efficacy) for a select group of supervisor competencies?, (2) Are there differences in self-efficacy as a function of their supervision experience or their genetic counseling experience, and 3) What training methods do they use and prefer to develop supervision skills? One-hundred thirty-one genetic counselor supervisors completed an anonymous online survey assessing demographics, self-efficacy (self-perceived capability) for 12 goal setting and 16 feedback competencies (Scale: 0-100), competencies that are personally challenging, and supervision training experiences and preferences (open-ended). A MANOVA revealed significant positive effects of supervision experience but not genetic counseling experience on participants' self-efficacy. Although mean self-efficacy ratings were high (>83.7), participant comments revealed several challenging competencies (e.g., incorporating student's report of feedback from previous supervisors into goal setting, and providing feedback about student behavior rather than personal traits). Commonly preferred supervision training methods included consultation with colleagues, peer discussion, and workshops/seminars.

  14. Maximizing work integration in job placement of individuals facing mental health problems: Supervisor experiences.

    Science.gov (United States)

    Skarpaas, Lisebet Skeie; Ramvi, Ellen; Løvereide, Lise; Aas, Randi Wågø

    2015-01-01

    Many people confronting mental health problems are excluded from participation in paid work. Supervisor engagement is essential for successful job placement. To elicit supervisor perspectives on the challenges involved in fostering integration to support individuals with mental health problems (trainees) in their job placement at ordinary companies. Explorative, qualitative designed study with a phenomenological approach, based on semi-structured interviews with 15 supervisors involved in job placements for a total of 105 trainees (mean 7, min-max. 1-30, SD 8). Data were analysed using qualitative content analysis. Superviors experience two interrelated dilemmas concerning knowledge of the trainee and degree of preferential treatment. Challenges to obtaining successful integration were; motivational: 1) Supervisors previous experience with trainees encourages future engagement, 2) Developing a realistic picture of the situation, and 3) Disclosure and knowledge of mental health problems, and continuity challenges: 4) Sustaining trainee cooperation throughout the placement process, 5) Building and maintaining a good relationship between supervisor and trainee, and 6) Ensuring continuous cooperation with the social security system and other stakeholders. Supervisors experience relational dilemmas regarding pre-judgment, privacy and equality. Job placement seem to be maximized when the stakeholders are motivated and recognize that cooperation must be a continuous process.

  15. Quality assessment and comparison of grading between examiners and supervisors of Bachelor theses in nursing education.

    Science.gov (United States)

    Lundgren, Solveig M; Halvarsson, Maud; Robertsson, Barbro

    2008-01-01

    This study compares supervisors' and examiners' grading of quality of theses at Bachelor level in nursing. An instrument developed to asses the quality of theses was used. Eight aspects of quality were rated. One hundred and fifteen theses were rated by both examiner and supervisor. Significant correlations were found between examiners' and supervisors' ratings of all aspects of quality. Good agreement was found in 89-96% of the ratings on individual aspects of quality. The means of differences between ratings were small but significantly differed from zero in four out of eight aspects. In theses rated low for quality of language and formality, differences between examiners' and supervisors' ratings on all aspects of quality were significantly larger than in theses rated high for quality of language and formality. The general conclusion is that the evaluations made by examiners and by supervisors corresponded well. Differences found indicates that examiners in general give lower scores than supervisors especially on quality aspects that are most closely related to research methods and experiences. This study is part of a larger project that is investigating quality of theses and the student's attitudes and learning experiences of writing theses.

  16. PELATIHAN MERAMU CAIRAN PEMBASMI JENTIK NYAMUK DARI DAUN SIRIH (Piper betle L. DI DESA TIBUBIU KECAMATAN KERAMBITAN TABANAN

    Directory of Open Access Journals (Sweden)

    I M. Sukadana

    2012-10-01

    Full Text Available The Community Service activity about the manner of making natural mosquito antilarvae liquids from Piper betle L leaf was conducted on the 24st of October 2010 to the mothers of PKK of Tibubiu village, Kerambitan subdistrict, Tabanan district. Making natural mosquito antilarvae liquids from Piper betle L leaf used the simple formulation technique. The liquids were made by using petroleum as a solvent and Piper betle L leaf as a antilarvae agent. The result of this activity and evaluation showed that the mosquito antilarvae liquids product is as good as chemical agent like “abate”. All participants showed enthusiastic during the activity and they will try to make these liquids. All participants, moreover understand about making liquids and they want to try at home. Such public service is interesting to because the peoples have improved knowledge, skill, and possibility to open of new entrepreneur in village so that it can be vacancy and increase income to community.

  17. The difference of salivary pH before and after toothbrushing with toothpaste containing Betel leaf (Piper Betle

    Directory of Open Access Journals (Sweden)

    Soo Ling Fu

    2014-11-01

    Full Text Available There has been a long history of the use of plants to improve dental health and oral hygiene. The purpose of this research was to find out the difference of salivary pH before and after toothbrushing with toothpaste containing betel leaf (Piper betel. The type of research used was quasi-experimental. Data collected were analyzed by using a paired t-test. The result shows that there is an increase of salivary pH by an average of 0.48 after toothbrushing with toothpaste containing betel leaf (Piper betel. In conclusion, there is the difference between the salivary pH before and after toothbrushing with toothpaste containing betel leaf (Piper betel.

  18. Identification and simultaneous quantification of five alkaloids in Piper longum L. by HPLC-ESI-MS(n) and UFLC-ESI-MS/MS and their application to Piper nigrum L.

    Science.gov (United States)

    Liu, Hao-Long; Luo, Rong; Chen, Xiao-Qing; Ba, Yin-Ying; Zheng, Li; Guo, Wei-Wei; Wu, Xia

    2015-06-15

    A simple, effective and suitable UFLC-ESI-MS/MS method was firstly developed to simultaneously determine five characteristic constituents (piperine, piperlonguminine, Δα,β-dihydropiperlonguminine, pellitorine and piperanine) of Piper longum L. The total alkaloids of P. longum L. was prepared. The alkaloid contents of Piper nigrum L. and P. longum L. were compared. The analysis was carried out in multiple reaction monitoring scan mode. The method showed a good specificity, linearity (R(2)>0.995), stability (RSDnigrum, P. longum had lower piperine content but was enriched in the other four alkaloids.

  19. Exploring the Relationship between Ethical Leadership and Job Satisfaction with the Mediating Role of the Level of Loyalty to Supervisor

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    Tarhan Okan

    2015-10-01

    Full Text Available The purpose of this study was to examine the impact of ethical leadership behaviour on employees’ both intrinsic and extrinsic job satisfaction and also to find out a possible mediator effect of loyalty to supervisor in this relationship. A total of 223 academic and administrative staff who worked in Gümüşhane University in Turkey constituted the sample of the study. Mediation analysis was used to test the research model. Findings of our analysis have confirmed that ethical leadership is effective on loyalty to supervisor and also loyalty to supervisor increases employees’ job satisfaction. It was understood that from the intrinsic dimension side of job satisfaction, indirect effect had been defined over “Extra Effort for Supervisor, Identification with Supervisor and Internalization of Supervisor’s Values” dimensions of loyalty to supervisor. On the extrinsic dimension side of job satisfaction, “Dedication and Attachment to Supervisor (Ded*Attach, Identification with Supervisor and Internalization Supervisor’s Values” dimensions of loyalty to supervisor variable had mediated the relationship between ethical leadership and job satisfaction. Briefly, as a result of mediator analysis we confirmed that a certain part of the relationship between ethical leadership and job satisfaction came out over loyalty to supervisor.

  20. A study of the free radical scavenging effects of Piper betle leaf extract in patients with vitiligo

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    Sneha Mitra

    2017-01-01

    Full Text Available Background: Vitiligo is an idiopathic skin disease manifested by depigmented macules. It is characterised by melanocyte destruction, and redox imbalance is proposed to play a contributory role. Aim: The aim of this study was to analyze the effects of an ethanolic extract of Piper betle leaves on the generation of reactive oxygen species in erythrocytes sourced from vitiligo patients. Methods: The effect of Piper betle on the generation of reactive oxygen species in erythrocytes was measured by flow cytometry in patients with active and stable vitiligo versus healthy controls, using 5-(and-6-chloromethyl-2'-7'-dichlorodihydrofluorescein diacetate. Results: The generation of reactive oxygen species in erythrocytes was higher in patients with vitiligo (n = 23 compared to healthy controls (n = 18. The geometrical mean fluorescence channel was 23.05 ± 2.11 in patients versus 17.77 ± 1.79 in controls, P = 0.039. The levels of reactive oxygen species were higher in patients with active vitiligo. Treatment of erythrocytes with Piper betle in concentrations of 0.5 and 1.0 μg/ml significantly decreased the baseline levels of reactive oxygen species by 31.7% in healthy controls, and 47.6% and 44.3% in patients with active vitiligo, respectively. Piper betle effectively scavenged hydrogen peroxide, which was evident by a decrease in the geometrical mean fluorescence channel by 52.4% and 62.9% in healthy controls, and 45.0% and 57.0% in patients with active vitiligo. Limitations: The study had a small sample size. Future studies should focus on evaluation of the antioxidant role of Piper betle at the lesional site. Conclusion: This pilot study indicates that patients with active vitiligo demonstrate enhanced generation of reactive oxygen species in erythrocytes, which was significantly reduced following ex vivo treatment with Piper betle.