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Sample records for superior palpebral conjunctiva

  1. Congenital smooth muscle hamartoma of the palpebral conjunctiva.

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    Mora, L Evelyn; Rodríguez-Reyes, Abelardo A; Vera, Ana M; Rubio, Rosa Isela; Mayorquín-Ruiz, Mariana; Salcedo, Guillermo

    2012-01-01

    Smooth muscle hamartoma is defined as a disorganized focus or an overgrowth of mature smooth muscle, generally with low capacity of autonomous growth and benign behavior. The implicated tissues are mature and proliferate in a disorganized fashion. A healthy 5-day-old Mexican boy was referred to the authors' hospital in México city for evaluation of a "cystic" lesion of the right eye that had been noted since birth. The pregnancy and delivery were unremarkable. On physical examination, there was a reddish-pink soft lesion with a tender "cystic" appearance, which was probably emerging from the upper eyelid conjunctiva, which measured 2.7 cm in its widest diameter and transilluminated. Ultrasound imaging revealed an anterior "cystic" lesion with normally formed phakic eye. An excisional biopsy was performed, and the lesion was dissected from the upper tarsal subconjunctival space. Subsequent histologic and immunohistochemical findings were consistent with the diagnosis of congenital smooth muscle hamartoma (CSMH) of the tarsal conjunctiva. The authors' research revealed that only one case of CSMH localized in the conjunctiva (Roper GJ, Smith MS, Lueder GT. Congenital smooth muscle hamartoma of the conjunctival fornix. Am J Ophthalmol. 1999;128:643-4) has been reported to date in the literature. To the best of the authors' knowledge, this current case would be the second case reported of CSMH in this anatomic location. Therefore, the authors' recommendation is to include CSMH in the differential diagnosis of a cystic mass that presents in the fornix and palpebral conjunctiva.

  2. Histopathologic Analysis of Palpebral Conjunctiva in Thyroid-Related Orbitopathy (An American Ophthalmological Society Thesis)

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    Kikkawa, Don O.

    2010-01-01

    Purpose: To examine the histopathology of palpebral conjunctiva in patients with thyroid-related orbitopathy. Based on previously published anecdotes, the hypothesis is that conjunctiva shows increased inflammation and fibrosis. Methods: This was a comparative case series. Superior palpebral conjunctiva was examined from two groups. The study group consisted of 20 patients undergoing thyroid-related upper eyelid retraction surgery. The control group consisted of 18 patients undergoing ptosis repair. Specimens were processed and stained using hematoxylin and eosin and trichrome. Histopathologic grading was performed using light microscopy. Main outcome measures were degree of inflammation and fibrosis, mast cell infiltration, and fibroblast count. Results: The two groups did not differ with regard to age or gender. Mean degree of inflammation was 1.4 (95% CI: 0.9, 1.9) for the control group and 1.7 (95% CI: 1.3, 2.1) for the study group. Relative intensity of blue from trichrome staining mean was 134.3 (95% CI: 130.3, 138.3) for the control group and 138.6 (95% CI: 133.7, 143.6) for the study group. The Mann-Whitney test showed no difference between groups in inflammation (P=.17), relative blue intensity (P=.11), degree of mast cell infiltration (P=.61), and fibroblast count (P=.45). Point estimates show a trend toward greater inflammation in the study group. Conclusions: While there is a trend toward higher inflammation in the study group, the superior palpebral conjunctiva of patients with thyroid-related orbitopathy is largely spared from autoimmune changes. This has implications in surgical approaches to eyelid retraction repair. PMID:21212848

  3. A Kalman Filtering and Nonlinear Penalty Regression Approach for Noninvasive Anemia Detection with Palpebral Conjunctiva Images

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    Yi-Ming Chen

    2017-01-01

    Full Text Available Noninvasive medical procedures are usually preferable to their invasive counterparts in the medical community. Anemia examining through the palpebral conjunctiva is a convenient noninvasive procedure. The procedure can be automated to reduce the medical cost. We propose an anemia examining approach by using a Kalman filter (KF and a regression method. The traditional KF is often used in time-dependent applications. Here, we modified the traditional KF for the time-independent data in medical applications. We simply compute the mean value of the red component of the palpebral conjunctiva image as our recognition feature and use a penalty regression algorithm to find a nonlinear curve that best fits the data of feature values and the corresponding levels of hemoglobin (Hb concentration. To evaluate the proposed approach and several relevant approaches, we propose a risk evaluation scheme, where the entire Hb spectrum is divided into high-risk, low-risk, and doubtful intervals for anemia. The doubtful interval contains the Hb threshold, say 11 g/dL, separating anemia and nonanemia. A suspect sample is the sample falling in the doubtful interval. For the anemia screening purpose, we would like to have as less suspect samples as possible. The experimental results show that the modified KF reduces the number of suspect samples significantly for all the approaches considered here.

  4. In vivo confocal microscopy of meibomian glands and palpebral conjunctiva in vernal keratoconjunctivitis

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    Qiaoling Wei

    2015-01-01

    Full Text Available Purpose: To investigate the correlations between conjunctival inflammatory status and meibomian gland (MG morphology in vernal keratoconjunctivitis (VKC patients by using in vivo confocal microscopy (CM. Materials and Methods: Nineteen VKC patients (7 limbal, 7 tarsal, and 5 mixed forms and 16 normal volunteers (controls were enrolled. All subjects underwent CM scanning to obtain the images of upper palpebral conjunctiva and MGs. Inflammatory cell (IC density in palpebral conjunctival epithelial and stromal layers, Langerhans cell (LC density at lid margins and the stroma adjacent to the MG, and MG acinar unit density (MGAUD were recorded. The longest and shortest diameters of MG acinar were measured. The Kruskal-Wallis test was used to compare the parameter differences whereas the Spearman′s rank correlation analysis was applied to determine their correlations. Results: Among all groups, no significant statistical differences were found in epithelial and stromal IC densities, mean values of MG acinar unit densities, or longest and shortest diameters. Both LC parameters in the tarsal-mixed groups were significantly higher than those in the limbal and control groups. All LC densities of VKC patients showed a positive correlation with MGAUD and shortest diameter. Conclusions: In VKC patients, the conjunctival inflammatory status could be associated with the MG status. In vivo CM is a noninvasive, efficient tool in the assessment of MG status and ocular surface.

  5. Transmissible venereal tumor in the palpebral conjunctiva of a dog: case reportTumor venéreo transmissível na conjuntiva palpebral de um cão – relato de caso

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    Luciane de Albuquerque

    2011-08-01

    Full Text Available The transmissible venereal tumor (TVT is a contagious neoplasm that occurs in sexually mature dogs, usually transmitted by coitus. This tumor normally affects the genital mucosa and is rarely found in any other part of the body. A case of transmissible venereal tumor in the palpebral conjunctiva of a 3-year old, crossbreed, male dog with a history of an abnormal mass in the right eye was presented. Ophthalmic examination revealed a mass originated from the lower eyelid conjunctiva of the right eye. No other ocular abnormalities were detected. Cytological examination was carried out and the diagnosis was TVT. The dog was treated with lyophilized vincristine sulphate intravenously, once a week, for four weeks. Despite the atypical clinical presentation, the response to chemotherapy with vincristine was excellent leading to complete regression of the neoplasm and no relapse after a year.O tumor venéreo transmissível (TVT é uma neoplasia contagiosa que ocorre em cães sexualmente maduros, sendo geralmente transmitido pelo coito. A neoplasia normalmente afeta a mucosa genital e é raramente encontrada em outras partes do corpo. Apresentamos um caso de tumor venéreo transmissível na conjuntiva palpebral de um cão macho, sem raça definida, com três anos de idade e histórico de presença de uma massa na conjuntiva palpebral inferior do olho direito. Não foram detectadas outras alterações oculares. O diagnóstico citológico da massa foi TVT. O cão foi tratado com sulfato de vincristina por via intravenosa, uma vez por semana, durante quatro semanas. Embora a apresentação do caso seja atípica, a resposta à quimioterapia foi excelente, levando a regressão completa da neoplasia, sem recorrência após um ano.

  6. Construção do sulco palpebral superior em pacientes orientais sem incisão cirúrgica: experiência em 13 anos

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    Aki Fábio Ezo

    2003-01-01

    Full Text Available A blefaroplastia em pacientes orientais jovens tem como principal objetivo a construção do sulco palpebral superior. Existem inúmeras técnicas cirúrgicas com tal propósito, podendo ser divididas em 2 grandes grupos: métodos com incisão cirúrgica (blefaroplastia clássica e métodos sem incisão cirúrgica ou com incisões cirúrgicas mínimas. OBJETIVO: Apresentar a técnica sem incisão cirúrgica, a importância do planejamento pré-operatório, as principais indicações e as modificações para cada tipo de paciente. MÉTODO: No período de janeiro de 1989 a janeiro de 2002 (13 anos, foram operados 647 pacientes com a técnica sem incisão cirúrgica. Inicialmente, usávamos a técnica com 3 pontos para a confecção do sulco. A partir de 1996, foi iniciado o uso da técnica com apenas dois pontos, sendo operado 308 pacientes (47,60% com essa técnica até 2002. Os pacientes foram acompanhados ambulatorialmente por período médio de 2 anos. RESULTADOS: Foram extremamente satisfatórios e foram necessárias reoperações em 19 pacientes (2,93% por causa da assimetria na altura dos sulcos e em 12 (1,85% devido à queixa de sulco pouco visível e estreito. No planejamento pré-operatório deve-se determinar a forma do sulco e a quantidade de pontos necessária, de acordo com a espessura da pele da pálpebra. Do total, 97,84% dos pacientes desejaram um sulco que se iniciava junto à prega epicantal, pois oferecia resultado mais natural. CONCLUSÃO: A técnica é de fácil execução, de pequeno risco cirúrgico e com poucas complicações, apresentando resultado satisfatório, natural e duradouro, mas sua indicação deve ser precisa e o planejamento pré-operatório é determinante para se obter um bom resultado.

  7. Posicionamento palpebral superior e inferior em diferentes graus de rotação ocular ao longo do meridiano vertical Upper and lower eyelid position in different degrees of downgaze and upgaze

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    Dante Augusto Mastropietro

    2009-12-01

    Full Text Available OBJETIVO: Quantificar a relação entre o posicionamento do olho e das pálpebras, em diferentes posições do olhar, ao longo do meridiano vertical, em indivíduos normais. MÉTODOS: Foi quantificada a posição das pálpebras superior e inferior e do olho, de dez indivíduos normais, por meio do processamento da imagem da fenda palpebral usando o programa NIH Image. Foram medidas as distâncias margem-centro pupilar superior e inferior em sete posições do olhar ao longo do meridiano vertical, ou seja -30, -20, -10, 0, +10, +20 e +30 graus (sinais: negativos infraducção e positivos supraducção. RESULTADOS: Em relação à distância margem superior-centro da pupila, nota-se que o maior valor é obtido na posição primária do olhar, ou seja, tanto quando se olha para cima, como para baixo, essa distância diminui. A redução na distância margem superior-centro da pupila é um pouco maior no olhar para cima. Em relação à distância margem inferior-centro da pupila, nota-se que o valor é maior no olhar para cima e menor no olhar para baixo, em relação à posição primária do olhar. No que tange à fenda palpebral, pode-se notar que no olhar para cima a fenda aumenta até 20 graus de rotação ocular. No olhar para baixo, ela diminui. CONCLUSÃO: Os dados do presente trabalho mostram que a altura da fenda palpebral varia de acordo com a amplitude da mirada vertical e que considerações sobre o valor da magnitude da distância entre a margem palpebral e o centro da pupila devem levar em conta o grau de rotação ocular vertical.PURPOSE: To quantify the relation between eye and eyelids placement in different positions during downgaze and upgaze in healthy subjects. METHODS: The position of the eye and eyelids of 10 healthy individuals was quantified by palpebral fissure image processing with NIH Image software. Upper and lower mid-pupil margin distance was measured in 7 positions: -30, -20, -10, 0, +10, +20 and +30 degrees

  8. Efeito da facectomia no posicionamento palpebral superior: comparação entre as técnicas de facoemulsificação e a extracapsular Changes in the position of the upper eyelid after cataract surgery: a comparison between phacoemulsification and extracapsular techniques

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    Roberto Pinto Coelho

    2003-10-01

    Full Text Available OBJETIVO: Comparar o efeito de duas técnicas de facectomia (facoemulsificação e extracapsular no posicionamento da pálpebra superior. MÉTODOS: Foi analisado o posicionamento palpebral de dois grupos de pacientes submetidos à cirurgia de catarata: facoemulsificação e extracapsular. As imagens foram digitalizadas (antes e 30 dias após a cirurgia e processadas com o programa NIH 1.62. O posicionamento palpebral foi medido em relação a uma linha horizontal que unia os cantos medial e lateral da fenda palpebral, passando pelo centro da pupila. RESULTADOS: O posicionamento palpebral foi afetado de maneira diferente segundo a técnica utilizada. Na facoemulsificação a diferença média entre a posição palpebral superior pós e pré-operatória foi de -0,54 mm. Na extracapsular esta diferença aumentou para -1,41 mm. O teste t de Student (amostras pareadas mostrou que as médias das diferenças entre os dois grupos são significativamente diferentes (p=0,0068. CONCLUSÃO: A técnica de cirurgia de facoemulsificação induziu menor variação do posicionamento palpebral em relação à cirurgia extracapsular no pós-operatório recente.PURPOSE: To compare changes in the upper eyelid position after cataract surgery with phacoemulsification and extracapsular techniques. METHODS: The upper eyelid position was measured in two groups of patients before and 30 days after cataract surgery performed with phacoemulsification and extracapsular techniques. Palpebral fissure images (before and after the cataract surgery were digitized and then processed using the NIH 1.62 software. Eyelid position was measured relative to a horizontal line passing through the pupil center and connecting both canthi of the palpebral fissure. RESULTS: The palpebral position was differently affected according to the techniques. In phacoemulsification the mean difference between eyelids position before and after surgery was -0.54 mm. In the extracapsular technique this

  9. Canine Bilateral Conjunctivo-Palpebral Dermoid: Description of Two Clinical Cases and Discussion of the Relevance of the Terminology

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    O. Balland

    2015-01-01

    Full Text Available Two young dogs were presented for the evaluation of an abnormally haired appearance of both eyes since adoption. In one dog, the lesions were symmetrical and appeared as disorganized skin tissue located on the cutaneous aspect of the lateral portion of both lower eyelids, and continuing to the palpebral and the bulbar conjunctiva, thus forming continuous lesions. In the other dog, a similar lesion was present in the right eye (OD, but the lesion of the left eye (OS was of discontinuous, disorganized skin tissue located midway on the lower eyelid and on the lateral bulbar conjunctiva. The lesions were surgically removed and routinely processed for histopathological analysis. Definitive diagnosis was conjunctivo-palpebral dermoids for each dog. Dermoids are usually considered to be choristoma (normal tissue in an abnormal location when they are located on the ocular surface (cornea and/or conjunctiva and as hamartoma when located on the palpebral skin. The lesion presentation in these two dogs reveals that names of “choristoma” alone or “hamartoma” alone are not accurate to depict the continuous, composite, conjunctivo-palpebral dermoids. These cases suggest that choristoma and hamartoma might develop subsequently from the same abnormal event during the embryonic development, which means that the lesion location might be the only difference between the two terms.

  10. Non-Invasive Detection of Anaemia Using Digital Photographs of the Conjunctiva.

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    Collings, Shaun; Thompson, Oliver; Hirst, Evan; Goossens, Louise; George, Anup; Weinkove, Robert

    2016-01-01

    Anaemia is a major health burden worldwide. Although the finding of conjunctival pallor on clinical examination is associated with anaemia, inter-observer variability is high, and definitive diagnosis of anaemia requires a blood sample. We aimed to detect anaemia by quantifying conjunctival pallor using digital photographs taken with a consumer camera and a popular smartphone. Our goal was to develop a non-invasive screening test for anaemia. The conjunctivae of haemato-oncology in- and outpatients were photographed in ambient lighting using a digital camera (Panasonic DMC-LX5), and the internal rear-facing camera of a smartphone (Apple iPhone 5S) alongside an in-frame calibration card. Following image calibration, conjunctival erythema index (EI) was calculated and correlated with laboratory-measured haemoglobin concentration. Three clinicians independently evaluated each image for conjunctival pallor. Conjunctival EI was reproducible between images (average coefficient of variation 2.96%). EI of the palpebral conjunctiva correlated more strongly with haemoglobin concentration than that of the forniceal conjunctiva. Using the compact camera, palpebral conjunctival EI had a sensitivity of 93% and 57% and specificity of 78% and 83% for detection of anaemia (haemoglobin anaemia. Erythema index of the palpebral conjunctiva calculated from images taken with a compact camera or mobile phone correlates with haemoglobin and compares favourably to clinician assessment for prediction of anaemia. If confirmed in further series, this technique may be useful for the non-invasive screening for anaemia.

  11. Ptose palpebral causada por Paquidermoperiostose

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    Patricia Regina de Pinho Tavares

    2014-08-01

    Full Text Available A paquidermoperiostose é uma síndrome caracterizada por acometimento cutâneo e ósseo, e em alguns casos ocorre comprometimento palpebral leve. É uma síndrome rara, idiopática ou hereditária, com provável herança autossômica dominante de penetrância variável. Descreve-se o caso de um paciente com ptose grave por paquidermoperiostose elucidando sua fisiopatologia e conduta cirúrgica aplicada.

  12. Diminuição da função do músculo levantador da pálpebra superior em pacientes submetidos à cirurgia de ptose palpebral involucional e dermatocálase Decrease of upper eyelid levator muscle function after involutional ptosis and dermatochalasis surgery

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    Eliana Forno

    2008-12-01

    Full Text Available OBJETIVO: Avaliar a diferença da função do músculo levantador da pálpebra superior (FMLPS, distância margem reflexo (DMR1 e altura do sulco palpebral (AS antes e depois da cirurgia de blefaroplastia superior associada à correção de ptose palpebral. MÉTODOS: Quarenta e quatro pacientes com blefaroptose e dermatocálase foram incluídos. Intervenção: exploração do tendão do músculo levantador da pálpebra superior (MLPS durante a blefaroplastia, em portadores de blefaroptose e dermatocálase. Nos casos de desinserção, o tendão foi refixado ao tarso. Desfechos analisados: foram analisados de forma bilateral a diferença entre FMLPS, DMR1 e AS antes e depois da intervenção. A dependência entre os olhos foi corrigida por meio de equações de estimativa generalizada. Foi utilizada a correlação de Pearson para quantificar a dependência entre os olhos para FMLPS, DMR1 e AS. RESULTADOS: Houve diferença significante entre as medidas de FMLPS antes e depois da cirurgia, havendo redução da excursão do MLPS após a cirurgia, diminuindo, em média, 1,1 mm (P0,01. CONCLUSÃO: A função do músculo levantador da pálpebra superior diminui após a cirurgia para a correção da ptose.PURPOSE: To evaluate the differences between upper eyelid levator muscle function (UELMF, margin reflex distance (MDR1, and eyelid crease height (ECH before and after ptosis and dermatochalasis surgery. METHODS: Forty-four patients with blepharoptosis and dermatochalasis were enrolled. Intervention: An exploration of the levator tendon (LT during a blepharoplasty procedure in patients with blepharoptosis and dermatochalasis and in case of its disinsertion, the tendon was reattached to the tarsus. Measured outcome: The differences between UELMF, MDR1, ECH before and after surgery were evaluated bilaterally. Dependency between both eyes was corrected by generalized estimating equations. Pearson correlation was used to evaluate the dependency of the two

  13. Mucoepidermoid carcinoma of the conjunctiva.

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    Gamel, J W; Eiferman, R A; Guibor, P

    1984-05-01

    A 73-year-old man had a limbal nodule that, on histopathologic examination, proved to be mucoepidermoid carcinoma of the conjunctiva. Despite radiation therapy and extensive corneoscleral lamellar resection, widespread invasion of the lids and orbit ultimately led to exenteration. Although mucoepidermoid carcinoma of the conjunctiva resembles squamous cell carcinoma clinically and histopathologically, it pursues a more rapid and destructive clinical course. Intraepithelial invasion often leads to tumor involvement of conjunctiva and skin that seem normal on clinical examination. Special stains and a high level of suspicion are required for diagnosis of mucoepidermoid carcinoma of the conjunctiva, and proper initial management demands more aggressive surgical resection than is usually indicated for squamous cell carcinoma.

  14. Rhinosporidiosis of the tarsal conjunctiva

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    Akshay Gopinathan Nair

    2015-01-01

    Full Text Available Rhinosporidiosis is a rare infection caused by Rhinosporidium seeberi, an organism classified in its own class, mesomycetozoea. It commonly affects mucus membranes namely the nasal mucosa, pharynx and the conjunctiva. We present the case of an 8-year-old female who presented with a flat, red, vascular, fleshy, pedunculated mass arising from the tarsal conjunctiva of the right upper eyelid. The mass was completely excised. On histopathological examination, multiple sporangia were seen in various stages of degeneration, consistent with rhinosporidiosis. The diagnosis of rhinosporidiosis is based solely on its microscopic features, and the treatment is surgical excision. This condition is endemic in the temperate regions of the Indian subcontinent, but it has been known to occur even in the colder regions of North America and Eastern Europe. Although a rare clinical entity, the possibility of rhinosporidiosis must be borne in mind when evaluating any polypoidal conjunctival mass.

  15. Palpebral myiasis in a Danish traveler caused by the human bot-fly (Dermatobia hominis)

    DEFF Research Database (Denmark)

    Bangsgaard, Regitze; Holst, Bengt; Krogh, Erik

    2000-01-01

    ophthalmology, dermatobia hominis, human bot-fly, palpebral myiasis, parasite infection, myiasis......ophthalmology, dermatobia hominis, human bot-fly, palpebral myiasis, parasite infection, myiasis...

  16. Transposição da rima palpebral em ptose miogênica mitocondrial

    OpenAIRE

    Lucci, Lucia Miriam Dumont [UNIFESP; Fonseca Junior,Nilson Lopes da; Sugano,Débora Mayumi; Silvério,Juliana

    2009-01-01

    OBJETIVO: Relatar o uso da ressecção do tarso da pálpebra superior e enxerto na pálpebra inferior para a elevação da rima palpebral e liberação do eixo visual, sem causar complicações corneanas em pacientes portadores de ptose miogênica mitocondrial. MÉTODOS: Estudo prospectivo. A técnica cirúrgica consiste na tarsectomia da pálpebra superior e autoenxerto do tarso na lamela posterior da pálpebra inferior. As cirurgias foram realizadas sob anestesia local. No caso de diplopia, a cirurgia foi ...

  17. Application of Palpebral Spring in Asian Patients With Paralytic Lagophthalmos.

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    Chan, Richie Chiu-Lung; Chan, Jimmy Yu-Wai

    Literature on palpebral springs is scarce, and even more so for the Asian population. In this study, the authors evaluated their experience with palpebral spring placement for paralytic lagophthalmos in an Asian population. The authors report the unique challenges encountered due to the distinctive features in Asian eyelids and how they overcome them. To the best of our knowledge, this is the first report on the application of palpebral springs in Asians. All patients treated for paralytic lagophthalmos in the Department of Surgery, Queen Mary Hospital, from November 2013 to December 2015, were included in this study. The authors retrieved and analyzed the demographic data, preoperative assessment details, and treatment outcomes. A total of 17 patients were recruited. The median interval between facial palsy occurrence and surgery was 66 months. Preoperatively, vertical palpebral fissure was 12.3 ± 1.7 mm with margin reflex distance 1 of 3.7 ± 0.3 mm and margin reflex distance 2 of 8.6 ± 1.6 mm. Lagophthalmos before surgery was 9.6 ± 2.3 mm. After the palpebral spring surgeries, vertical palpebral fissure was reduced to 9.1 ± 1.4 mm. margin reflex distance 1 is slightly reduced (3.3 ± 0.8 mm) and margin reflex distance 2 improved to 5.8 ± 1.0 mm. Lagophthalmos reduced significantly to 0.8 ± 1.3 mm. Seven patients required revision procedures. Palpebral spring is a safe and effective treatment for Asian patients with paralytic lagophthalmos. However, surgeons should be aware of the unique challenges associated with the anatomy of Asian eyelids. Special adaptation of the procedure is required to optimize the outcome.

  18. [Leukoplakia of the lower tarsal conjunctiva].

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    Dierks, P; Wiegand, W

    2012-10-01

    The case of a 73-year-old woman with a perforated corneal ulcer in the remaining eye with migrating endophthalmitis is presented. In addition, the affected eye had non-abradable whitish coating (leukoplakia) on the tarsal conjunctiva. The cause of leukoplakia was initially histologically diagnosed after an incisional biopsy as focal invasive sebaceous carcinoma with pagetoid growth. After exenteration of the orbit it was confirmed to be an early invasive, non-keratinizing squamous cell carcinoma (G2) of the conjunctiva, which had emerged from a spinocellular carcinoma in situ. The early histological differentiation of malignant lesions in the conjunctiva can be extremely difficult because the pathological changes in the tissue are very similar due to the cell metaplasia.

  19. Análise morfométrica da fenda palpebral de pacientes com retração palpebral na fase aguda da orbitopatia distireoidiana submetidos à injeção palpebral de toxina botulínica tipo A Morphometric analysis of eyelid fissure in patients with eyelid retraction in acute stage of dysthyroid orbitopathy after treatment with botulinum toxin type A

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    Patrícia Grativol Costa

    2008-08-01

    Full Text Available OBJETIVO: Apresentar dados morfométricos da fenda palpebral, antes e após a aplicação da toxina botulínica tipo A em pacientes com retração palpebral na fase aguda da orbitopatia distireoidiana. MÉTODOS: Estudo prospectivo com 12 indivíduos submetidos à aplicação de 5 UI/0,1 ml de toxina botulínica tipo A em uma das pálpebras superiores. O seguimento mínimo foi de 6 meses. A avaliação palpebral foi registrada por meio de captação de imagens com uma câmera filmadora de vídeo conectada a um microcomputador. RESULTADOS: As medidas da fenda palpebral vertical, distância da margem palpebral superior reflexo, área total da fenda palpebral e função do músculo levantador da pálpebra superior, apresentaram diminuição após a aplicação da droga. Houve diminuição, nos olhos tratados, da diferença entre a área lateral e a área medial da fenda palpebral. A distância margem palpebral inferior reflexo não mostrou alterações. No olho contralateral, houve aumento das medidas (fenda palpebral vertical, distância margem palpebral superior reflexo, área total da fenda palpebral até 2 semanas após a aplicação. CONCLUSÕES: Estes resultados mostram uma melhora da retração e do contorno palpebral superior, sem alterar o posicionamento da pálpebra inferior.PURPOSE: To compare morphometric data of eyelid fissure using computerized image analysis before and after application of botulinum toxin type A in patients with eyelid retraction caused by dysthyroid orbitopathy in acute stage. METHODS: This was a prospective study with 12 individuals that received transcutaneous 5 UI/0.1 ml injection of botulinum toxin in the upper eyelid. They were examined periodically for 6 months. Clinical eyelid examination was performed and re corded using a video camera connected to a microcomputer. RESULTS: Vertical eyelid fissure, upper eyelid margin to reflex distance and the eyelid area showed reduction in the treated eye. A decrease in

  20. Expression of filaggrin in normal and keratinized conjunctiva

    DEFF Research Database (Denmark)

    Lund, Anne Sofie Kragegaard; Heegaard, Steffen; Prause, Jan Ulrik

    2012-01-01

    We wanted to investigate filaggrin expression in normal conjunctiva and in conjunctiva exposed to different degrees of mechanical stress. Mechanical stress results in parakeratinization of the conjunctiva. If filaggrin is expressed in the milder forms of parakeratinization, it might be used as a ...

  1. Histopathology of Conjunctivochalasis Compared to Normal Conjunctiva

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    Hashemian, Hesam; Mahbod, Mirgholamreza; Amoli, Fahimeh A.; Kiarudi, Mohammad Y.; Jabbarvand, Mahmoud; Kheirkhah, Ahmad

    2016-01-01

    Purpose: To evaluate the histopathologic changes in the conjunctiva of patients with conjunctivochalasis (CCh) compared to age-matched controls. Methods: This cross-sectional, controlled study included 27 eyes of 27 patients with CCh and 16 eyes of 16 age-matched controls. A biopsy of the bulbar conjunctiva was performed along the temporal lower lid margin before cataract surgery in both groups. Histopathologic evaluation of the specimens was done with light microscopy using staining with hematoxylin/eosin, periodic acid Schiff, and van Gieson elastic stain. Various histopathologic features of the conjunctival epithelium and stroma were compared between the two groups. Results: The mean age of patients was 62.4 ± 6.9 years in the CCh group and 65.1 ± 6.3 years in the control group (P = 0.54). No significant differences were noted between the two groups in terms of conjunctival epithelial changes including papillomatosis, epithelial clefts, epithelial goblet cells, or infiltration of inflammatory cells. Mean thickness of the conjunctival stroma was 0.21 ± 0.08 mm in the CCh group and 0.26 ± 0.21 mm in the control group (P = 0.10). For the conjunctival stroma, there were no significant differences between the two groups in terms of elastosis, fibrosis, lymphangiectasia, or infiltration of inflammatory cells. Conclusion: No noticeable differences were found in the histopathologic features by light microscopy between eyes with CCh and those of age-matched controls. Therefore, the primary pathology of CCh may not be within the conjunctiva itself. Instead, loose attachment of the conjunctiva to the underlying tissue may be the reason for the redundant folds in the bulbar conjunctiva. PMID:27994801

  2. [Management of oculo-palpebral consequences in facial paralysis].

    Science.gov (United States)

    Alliez, A; Malet, T; Bertrand, B; Degardin, N; Benichou, L; Bardot, J; Labbé, D

    2015-10-01

    Facial paralysis prognostic depends on eye lesion. In this pathology, lacrymal and palpebral functions will be modified: bad eye closure and leak of tears secretions. It can leads to corneal complications from keratitis to corneal abcedation and visual dysfonction. This chapter details different procedures and their indications to avoid this kind of complications.

  3. Squamous cell carcinoma of the conjunctiva

    Directory of Open Access Journals (Sweden)

    Stephen Gichuhi

    2017-02-01

    Full Text Available Squamous cell carcinoma of the conjunctiva is the end-stage of a spectrum of disease referred to as ocular surface squamous neoplasia (OSSN. OSSN is a malignant disease of the eyes that can lead to loss of vision and, in severe cases, death. The main risk factors for both are exposure to solar ultraviolet radiation outdoors, HIV/AIDS, human papilloma virus and allergic conjunctivitis. The limbal epithelial cells appear to be the progenitors of this disease.

  4. [Modification of the conjuntival flora with cleaning palpebral solutions].

    Science.gov (United States)

    Hueso Abancens, J R; Mengual Verdú, E; Schargel Palacios, K; García Sánchez, J; Placeres Daban, J; García Conca, V; Zorraquino Marti, A

    2004-12-01

    The aim of the present study is to evaluate the effectiveness of a solution of palpebral hygiene during the preoperative stage of cataract surgery. We studied 286 patients divided in 5 groups. One control group that did not use the product, and the remaining 4, that used the product during 3, 4, 5 and 6 days. The design of the study was prospective, randomize and masked. We took a sample of the conjunctival fundus in the morning of the day of the surgery, before commencing treatment with eye drops. This sample was sown according to microbiological techniques and analyzed by the microbiology department. The best time for using palpebral hygiene solutions prior to cataract surgery is four to five days. If it is used at less than three days, it does not decrease the rate of positive cultures and if the solution is applied more than six days, microorganisms that are not part of the common conjunctival flora may appear. Palpebral hygiene products should not be used more than five consecutive days previous to surgery.

  5. [Lupus erythematosus panniculitis presenting as palpebral edema and parotiditis].

    Science.gov (United States)

    Pérez-Pastor, G; Valcuende, F; Tomás, G; Moreno, M

    2007-10-01

    Lupus erythematosus panniculitis or lupus erythematosus profundus is characterized by inflammation of the deep dermis and subcutaneous tissue. It can occur in isolation or associated with chronic systemic or discoid lupus erythematosus. It usually consists of nodules and hardened subcutaneous plaques on the forehead, cheeks, proximal extremities, and buttocks. Periorbital and parotid involvement are rare and can lead to misdiagnosis. We present the case of a patient with lupus erythematosus panniculitis who presented with palpebral edema and involvement of the periocular fat and parotid gland.

  6. Over-expression of human cystatin C in pterygium versus healthy conjunctiva.

    Science.gov (United States)

    Barba-Gallardo, Luis Fernando; Ventura-Juárez, Javier; Kershenobich Stalnikowitz, David; Gutiérrez-Campos, Rafael; Torres-Bernal, Eugenia; Torres-Bernal, Luis Fernando

    2013-02-27

    A prospective, non-randomised, transversal and comparative study, carried out in INOVA Vision Institute and Autonomous University of Aguascalientes. Pterygium is an important illness that affects 22% people from tropic and equatorial zones. Is an inflammatory process caused by UV rays, and it has a behavior similar to a neoplasm. For this study was taken into consideration 191 samples from the INOVA Vision Institute, Aguascalientes, Mexico. Include 73 pterygia samples, which were obtained during resection under sterile conditions. 44 normal conjunctiva samples were obtained from the same patients when harvesting the conjunctival autograft, or from other patients undergoing extracapsular cataract extraction from the superior bulbar region. Tears from patients with pterygium (n = 50) and normal volunteers (n = 24) were obtained using a calibrated glass micro capillary tube. The surgical conjunctiva and pterygia samples were subjected to reverse-transcription polymerase chain reaction (RT-PCR), western blot, and immunohistochemistry. Tears were analyzed by enzyme-linked immunosorbent assays. This was a prospective, non-randomised study involving 191 biological samples taken from patients with pterygium and normal volunteers, whom were operated under local anaesthesia by either complete resection of the lesion with primary closure, or resection with conjunctival autograft. Tissue samples were fixed in 10% formaldehyde. Sections were routinely stained with hematoxylin and eosin. HCC expression was evaluated by reverse-transcription polymerase chain reaction (RT-PCR), immunohistochemistry, and by western blotting. All tears samples were analyzed by enzyme-linked immunosorbent assays (ELISA). Expression levels and distribution patterns of HCC in normal conjunctiva and pterygium. Higher levels of HCC mRNAs and proteins were detected in pterygium compared with a normal conjunctiva. Immunohistochemistry revealed that HCC was localized in the apical cells of the epithelium in

  7. Goblet cells of the normal human bulbar conjunctiva and their assessment by impression cytology sampling.

    Science.gov (United States)

    Doughty, Michael J

    2012-07-01

    Goblet cells of the conjunctiva are the main source of mucus for the ocular surface. The objectives of this review are to consider the goblet cells as assessed by various histological, cytological and electron microscopy methods, and to assess the consistency of published reports (over more than 25 years) of goblet cell density (GCD) from impression cytology specimens from nominally healthy human subjects. Reported GCD values have been notably variable, with a range from 24 to 2226 cells/mm² for average values. Data analysis suggests that a high density of goblet cells should be expected for the healthy human conjunctiva, with a tendency toward higher values in samples taken from normally covered locations (inferior and superior bulbar conjunctiva) of the open eye (at 973 +/- 789 cells/ mm²) than in samples taken from exposed (interpalpebral) locations (at 427 +/- 376 cells/mm²). No obvious change in GCD was found with respect to age, perhaps because the variability of the data did not allow detection of any age-related decline in GCD. Analyses of published data from 33 other sources indicated a trend for GCD to be lower than normal across a spectrum of ocular surface diseases.

  8. Lupus palpebral: a propósito de dos casos

    Directory of Open Access Journals (Sweden)

    Irene Rojas Rondón

    Full Text Available El lupus eritematoso es una dermatosis inflamatoria, crónica, aguda o subaguda que evoluciona por brotes. Puede afectar a todos los órganos pero más frecuentemente a la piel. Presentamos a dos pacientes con lesión en forma de placa, localizada en zona interna y media del borde libre palpebral inferior, de bordes elevados, depresión central con fondo costroso y pérdida de las pestañas a ese nivel. Se decide -por la localización, extensión de la lesión, los antecedentes personales y la aplicación de tratamientos previos sin mejoría del cuadro clínico- realizar biopsia incisional para un mejor estudio. Los resultados anatomopatológicos revelaron el diagnóstico de lupus discoide palpebral. La evolución posterior al tratamiento médico fue satisfactoria, sin recidiva de la lesión durante el primer año de seguimiento.

  9. Tratamento cirúrgico da ptose palpebral adquirida (linfocitoma cútis Surgical treatment of acquired palpebral ptosis (lymphocitoma cutis

    Directory of Open Access Journals (Sweden)

    L.M. Ferreira

    1997-12-01

    Full Text Available Os autores descrevem um caso clínico de ptose palpebral causada por uma patologia rara, o linfocitoma cútis. A paciente apresentava o quadro clínico do linfocitoma cútis em sua forma disseminada, com sintomatologia visual causada por nódulos palpebrais. A conduta cirúrgica realizada foi a ressecção dos nódulos palpebrais por meio de incisão de blefaroplastia, e o exame histológico confirmou o diagnóstico de linfocitoma cútis. O tratamento cirúrgico realizado foi eficiente para a melhora funcional das pálpebras.A clinical case of acquired palpebral ptosis caused by a rare pathology, lymphocitoma cutis, is reported. An eyelid ptosis was characterized with the patient unable to lift the eyelid. The resection of the eyelid nodules was performed using blefaroplasty incision as access and the result of the anatomopathological examination confirmed the diagnosis: lymphocitoma cutis. The surgical result was satisfactory not only esthetically but also functionally (2-year follow-up.

  10. Photodynamic therapy for palpebral and conjunctival proliferative vascular tumors: clinical case report.

    Science.gov (United States)

    Sanchez, Carlos Gustavo; Caballero Chávez, Yolanda V; Plazola, Sara

    2009-01-01

    Photodynamic therapy (PDT) has been widely used in ophthalmology for the treatment of diverse pathologies, but no experience has been reported in the handling of patients with palpebral vascular and conjunctive malformations with PDT, we describe the case of one patient with a palpebral proliferative vascular tumor, treated successfully using the PDT as a new treatment alternative.

  11. Location and tension of the medial palpebral ligament.

    Science.gov (United States)

    Hwang, Kun; Huan, Fan; Nam, Yong Seok; Han, Seung Ho; Kim, Dae Joong

    2013-11-01

    The aim of this study was to elucidate the precise anatomic location and tension of the medial palpebral ligament (MPL). Eleven hemifaces of 10 fresh Korean adult cadavers were used in this study. Nine specimens were used for measurement of dissection and tension, and 2 were used for histologic study. Measurements of tensile strength of each part of the MPL and Horner muscle were performed using a force gauge.The MPL consisted of 2 layers in all specimens dissected. The superficial layer of the palpebral ligament (SMPL) was observed from the anterior lacrimal crest to the upper and lower tarsal plates. The deep layer of the palpebral ligament (DMPL) lay from the anterior lacrimal crest to the posterior lacrimal crest, covering the lacrimal sac. The Horner muscle was observed at the posterior lacrimal crest just lateral to the attachment of the DMPL and ran laterally to the tarsal plate deep to the SMPL. The SMPL began at 4.5 ± 2.3 mm lateral to the nasomaxillary suture line to the upper and lower tarsal plates. Its transverse length was 9.6 ± 1.5 mm, and vertical width was 2.4 ± 0.7 mm, and its thickness was 4.5 ± 2.3 mm. The transverse length of the DMPL was 3.7 ± 0.4 mm, and its vertical width was 2.9 ± 1.3 mm, with a thickness of 0.3 ± 0.1 mm. The transverse length of the Horner muscle was 7.6 ± 1.9 mm, and its vertical width was 4.06 ± 1.5 mm, with a thickness of 0.4 ± 0.1 mm. The tensile strength of the SMPL was 13.4 ± 3.2 N, that of the DMPL was 4.1 ± 1.7 N, and that for Horner muscle was 9.0 ± 3.1 N. The tensile strength of the SMPL was significantly higher than that of the DMPL (P = 0.003).We reconfirmed that the MPL consisted of 2 layers: superficial layer and deep layer. Our results might be of use in surgeries of the medial canthi.

  12. Diversity of bacteria at healthy human conjunctiva.

    Science.gov (United States)

    Dong, Qunfeng; Brulc, Jennifer M; Iovieno, Alfonso; Bates, Brandon; Garoutte, Aaron; Miller, Darlene; Revanna, Kashi V; Gao, Xiang; Antonopoulos, Dionysios A; Slepak, Vladlen Z; Shestopalov, Valery I

    2011-07-20

    Ocular surface (OS) microbiota contributes to infectious and autoimmune diseases of the eye. Comprehensive analysis of microbial diversity at the OS has been impossible because of the limitations of conventional cultivation techniques. This pilot study aimed to explore true diversity of human OS microbiota using DNA sequencing-based detection and identification of bacteria. Composition of the bacterial community was characterized using deep sequencing of the 16S rRNA gene amplicon libraries generated from total conjunctival swab DNA. The DNA sequences were classified and the diversity parameters measured using bioinformatics software ESPRIT and MOTHUR and tools available through the Ribosomal Database Project-II (RDP-II). Deep sequencing of conjunctival rDNA from four subjects yielded a total of 115,003 quality DNA reads, corresponding to 221 species-level phylotypes per subject. The combined bacterial community classified into 5 phyla and 59 distinct genera. However, 31% of all DNA reads belonged to unclassified or novel bacteria. The intersubject variability of individual OS microbiomes was very significant. Regardless, 12 genera-Pseudomonas, Propionibacterium, Bradyrhizobium, Corynebacterium, Acinetobacter, Brevundimonas, Staphylococci, Aquabacterium, Sphingomonas, Streptococcus, Streptophyta, and Methylobacterium-were ubiquitous among the analyzed cohort and represented the putative "core" of conjunctival microbiota. The other 47 genera accounted for ocular surface pathogens. The first DNA sequencing-based survey of bacterial population at the conjunctiva have revealed an unexpectedly diverse microbial community. All analyzed samples contained ubiquitous (core) genera that included commensal, environmental, and opportunistic pathogenic bacteria.

  13. Reconstrução palpebral com retalho de Fricke: relato de dois casos

    Directory of Open Access Journals (Sweden)

    Herzog Neto Guilherme

    2006-01-01

    Full Text Available O câncer de pele é o tumor mais comum na espécie humana, sendo o carcinoma basocelular o de maior prevalência. Este trabalho relata dois casos recentes deste tipo de tumor, envolvendo tanto a pálpebra superior quanto a inferior em duas mulheres. O primeiro caso é de uma mulher de 72 anos de idade, amaurótica do olho direito, com comprometimento de aproximadamente 80% da pálpebra superior esquerda, 70% da pálpebra inferior esquerda e comprometimento da parede lateral da órbita, comprovado pela tomografia computadorizada. O exame anatomopatológico da peça cirúrgica revelou a presença de carcinoma basocelular invasivo, com margens livres. Foi feita reconstrução imediata com retalho de Fricke. O segundo caso é de senhora de 68 anos de idade, com história prévia de trauma na região periorbitária esquerda, apresentando edema e hiperemia palpebral, com aspecto brilhante, com perda dos cílios e pequena ulceração central, envolvendo aproximadamente 90% da pálpebra superior e 65% da pálpebra inferior esquerda, com comprometimento da parede lateral da órbita evidenciado na tomografia. O exame anatomopatológico da peça cirúrgica revelou a presença de carcinoma basocelular invasivo, com margens livres. Foi optado pela reconstrução imediata com retalho de Fricke. Os autores acreditam que apesar deste tipo de retalho não ser a primeira escolha na maioria das reconstruções palpebrais, não deveria ser negligenciado, pois em certos casos, tornar-se-ia a única opção viável.

  14. Reanimación palpebral con colgajo frontal miofuncional: Caso clínico

    Directory of Open Access Journals (Sweden)

    F. García-García

    2014-06-01

    Full Text Available El párpado es una estructura crítica para la protección y función del globo ocular, y parte primordial en la estética facial. Su reconstrucción está determinada por la extensión de la lesión y el compromiso de las diferentes capas. Siempre se preferirán tejidos loco-regionales debido a su mayor similitud y disposición. Los métodos de reanimación palpebral se pueden dividir en estáticos y dinámicos, considerando a estos últimos como el único medio para restaurar el parpadeo. Presentamos un caso de celulitis orbitaria preseptal con lesión de espesor total del párpado superior y su reconstrucción miofuncional utilizando un colgajo frontal. Este colgajo frontal miocutáneo logró la restauración funcional del párpado comprometido mediante la adición de fibras musculares y permitiendo el fenómeno de reinervación.

  15. Effect of topical rebamipide on goblet cells in the lid wiper of human conjunctiva.

    Science.gov (United States)

    Kase, Satoru; Shinohara, Toshiya; Kase, Manabu; Ishida, Susumu

    2017-06-01

    It has been demonstrated that topical administration of rebamipide, which is an antiulcer agent, increases the mucin level of the tear film and ameliorates ocular surface conditions such as lid wiper epitheliopathy. The aim of the present study was to analyze the changes in goblet cell number, cell proliferation, and epidermal growth factor receptor (EGFR) induced by topical rebamipide addition to the lid wiper of humans. A total of 30 eyelid tissue samples were obtained during involutional entropion surgeries, fixed in paraformaldehyde, embedded in paraffin and divided into two groups: Rebamipide or non-rebamipide. The tissues in the rebamipide group were obtained from patients who had a medical history of topical rebamipide use prior to surgery. The number of goblet cells was counted under light microscopy. A total of 22 eyelid tissue samples were further examined using immunohistochemistry with anti-Ki-67 and anti-EGFR antibodies to evaluate cell proliferation and EGFR expression, respectively. Histologically, the lid wiper and palpebral conjunctiva were clearly identified in the tissues. The number of goblet cells was significantly higher in the rebamipide group compared with the non-rebamipide group (P=0.0367). There was no significant difference in lid wiper cell proliferation between the rebamipide and non-rebamipide groups. Immunohistochemistry revealed that EGFR levels in the lid wiper epithelial cells were significantly higher in the rebamipide group compared with the non-rebamipide group (P=0.0237). These results suggest that topical rebamipide application increases the number of goblet cells in the lid wiper, which in turn upregulates the expression of EGFR. These findings may be clinically relevant and provide a therapeutic basis for the treatment of ocular disease such as dry eye and lid wiper epitheliopathy.

  16. Annular elastolytic giant cell granuloma of conjunctiva: A case report

    Directory of Open Access Journals (Sweden)

    Karabi Konar

    2014-01-01

    Full Text Available Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. It usually occurs on sun-damaged skin and hence the previous name actinic granuloma. A similar process occurs on the conjunctiva. Over the past three decades only four cases of conjunctival actinic granuloma have been documented. All the previous patients were females with lesions in nasal or temporal bulbar conjunctiva varying 2-3 mm in size. We report a male patient aged 70 years presenting with a 14 mm × 7 mm fleshy mass on right lower bulbar conjunctiva. Clinical differential diagnoses were lymphoma, squamous cell carcinoma in situ and amyloidosis. Surgical excision followed by histopathology confirmed it to be a case of actinic granuloma. This is the first case of isolated conjunctival actinic granuloma of such a large size reported from India.

  17. Atypical presentation of pilomatrixoma in the tarsal conjunctiva

    Directory of Open Access Journals (Sweden)

    Mirtha Ramirez Dittrich

    2016-06-01

    Full Text Available ABSTRACT Pilomatrixoma is a rare benign tumor, which usually affects young women in the head and neck region. The eyelid is a common site of the disease, though it is very rare in the tarsal conjunctiva.The pilomatrixoma has clinical pleomorphism, which confuses this disease with other similar conditions. The diagnosis is made by pathological examination in most cases. The treatment is surgical, performed by total excision of the lesion with clear margins and recurrence is very uncommon.We present an unusual case of probable recurrent pilomatrixoma in the left upper tarsal conjunctiva.

  18. [De novo growth of a capillary hemangioma of the conjunctiva].

    Science.gov (United States)

    Fernández-Vega Cueto, L; Tresserra, F; de la Paz, M F

    2014-03-01

    A 22-year-old woman patient, diagnosed with an inclusion cyst of the conjunctiva in the nasal sector of the left eye, who after 2 shot/needle injections in the lesion came to our clinic with a dense subconjunctival hemorrhage in four quadrants and with severe pain. After excision biopsy, a capillary hemangioma of the conjunctiva was diagnosed. Conjunctival capillary hemangioma is mainly a benign lesion, asymptomatic and mostly congenital in origin, its progression or de novo growth is rare in adulthood. Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  19. Conjunctiva-associated lymphoid tissue in avian mucosal immunity

    NARCIS (Netherlands)

    Ginkel, van F.W.; Gulley, S.L.; Lammers, A.; Hoerr, F.J.; Gurjar, R.; Toro, H.

    2012-01-01

    Conjunctiva-associated lymphoid tissue’s (CALT) role in generating avian mucosal adaptive immunity was measured by analyzing cellular composition, expression of the polymeric immunoglobulin receptor (pIgR), and production of cytokines and antibodies in chickens ocular exposed to a replication-defici

  20. Estudo do raspado de conjuntiva e margem palpebral de pacientes tratados de retinoblastoma: etapa I - Microflora aeróbica Study of the conjunctival scrape and eyelid margin smears in patients treated for retinoblastoma: phase I - Aerobic microflora

    Directory of Open Access Journals (Sweden)

    Maria Carmen Menezes Santos

    2002-03-01

    Full Text Available Objetivo: A queixa de secreção ocular é muito freqüente entre os pacientes tratados de retinoblastoma submetidos à enucleação e radioterapia. A falta de dados sobre a microflora em pacientes nessas condições foi o que motivou este estudo. Métodos: Foram examinadas 114 órbitas de 58 pacientes. Este trabalho apresenta os resultados das culturas para bactérias aeróbicas e fungos, de conjuntiva e margem palpebral em 4 condições, com e sem enucleação, com e sem radioterapia. Procedeu-se à identificação dos microrganismos de acordo com o Protocolo do National Committee for Clinical Laboratory Standards e os esfregaços para citologia foram submetidos às colorações de Gram e Leishman. Resultados: A presença de microrganismos foi mais freqüente nas cavidades anoftálmicas irradiadas, tanto na conjuntiva (54,5% quanto na margem palpebral (63,6%, porém sem diferença estatisticamente significante. Além disso, em órbitas com bulbo ocular, a radiação, na fase tardia, representou um fator limitante da presença de microrganismos na conjuntiva e na margem palpebral, mas sem diferença estatisticamente significante. O Staphylococcus coagulase negativa foi o microrganismo mais freqüente na conjuntiva e margem palpebral de todos os grupos. Houve crescimento de fungo, Candida tropicalis, em apenas um caso. Conclusões: Sugere-se o uso de colírios antibióticos em pacientes tratados de retinoblastoma, portadores de cavidade anoftálmica, irradiada ou não.Purpose: Conjunctival discharge is a common complaint among patients treated for retinoblastoma who underwent enucleation and radiotherapy. Lack of data about the microflora in those patients motivated this study. Methods: One hundred and fourteen orbits of 58 patients were examined. The authors present the results of aerobic bacterial and fungal culture of conjunctival and eyelid margin smears, as well as conjunctival cytology, in 4 different conditions: with and without

  1. Induced corneal astigmatism by palpebral spring for the treatment of lagophthalmos.

    Science.gov (United States)

    Avni-Zauberman, Noah; Rosen, Nachum; Ben Simon, Guy J

    2008-08-01

    To report a patient with decreased vision after insertion of an upper eyelid palpebral spring. Interventional case report. A 44-year-old man presented with decreased vision in his right eye. Several months before presentation, he underwent palpebral spring insertion in his upper eyelid for lagophthalmos. He had developed seventh cranial nerve palsy after removal of the right facial nerve neuroma. Decreased vision was related to induced astigmatism by upper eyelid pressure. Surgical replacement of the spring resulted in less astigmatism and improvement in visual acuity. Ocular rehabilitation surgery with insertion of a palpebral spring to the upper eyelid may induce corneal astigmatism and decrease vision in the normal eye. This may be reversible by replacing or repositioning the spring so that it will imply less corneal pressure.

  2. Palpebral spring in the management of lagophthalmos and exposure keratopathy secondary to facial nerve palsy.

    Science.gov (United States)

    Demirci, Hakan; Frueh, Bartley R

    2009-01-01

    To evaluate the use of a palpebral spring, a dynamic facial reanimation technique, in the management of lagophthalmos and exposure keratopathy secondary to facial nerve palsy. A palpebral spring was placed in 29 eyelids of 28 patients with symptomatic facial nerve palsy. Preoperative and postoperative symptoms, upper eyelid margin to midpupil distance, lagophthalmos, and exposure keratopathy were evaluated. At an average of 83 months follow-up, preoperative symptoms improved or resolved in 26 (90%) eyes. The upper eyelid margin to midpupil distance decreased and lagophthalmos and exposure keratopathy significantly improved after palpebral spring placement (p lagophthalmos and exposure keratopathy in patients with facial nerve palsy who do not receive adequate relief from the static procedures of lower eyelid tightening and upper eyelid lowering. This technique significantly improved symptoms and signs in these patients while allowing some of the blink reflex.

  3. ¿Es necesaria la reconstrucción de la conjuntiva?: Trabajo experimental en conejos albinos para evaluar la neogénesis de la conjuntiva Is necessary the reconstruction of the conjunctiva?: Experimental research in albino rabbits to demostrate conjunctiva regeneration

    Directory of Open Access Journals (Sweden)

    E. A. Moretti

    2007-03-01

    Full Text Available En los defectos de espesor total del párpado inferior de gran magnitud, siempre ha sido regla de oro la reconstrucción de la lamela posterior (tarso y conjuntiva palpebral. Esto es debido a que el tono del músculo orbicularis oculi no alcanza a mantener el soporte necesario para resistir la acción de la gravedad y/o contractura cicatricial. Además la ausencia de conjuntiva provocaría lesiones sobre la córnea ocular. Es por ello que el empleo de injertos compuestos condromucosos ha sido insustituible. El presente trabajo de investigación fue realizado en 20 conejos albinos con el objeto de evaluar la posibilidad de emplear cartílago auricular para la reconstrucción del tarso sin colocación de mucosa a modo de conjuntiva sobre dicho cartílago. Los resultados obtenidos permiten confirmar por diferentes tinciones histológicas sobre biopsias comparadas con zonas testigo, el crecimiento de tejido conjuntival sobre el pericondrio sin provocar lesiones oculares (neogénesis de conjuntiva. Los hallazgos encontrados provocan importantes y sustanciales cambios en la cirugía reconstructiva del párpado inferior debido a que de esta manera, no sería necesaria la reconstrucción de la conjuntiva palpebral, siendo útil exclusivamente la colocación de cartílago.In a full-thickness defect of a lower eyelid, as a general rule, is mandatory to reconstruct the tarsal plate and the conjunctiva. The reason is that the orbicularis oculi muscle cannot support the effects of gravity and/or cicatricial contracture. The abscense of conjunctiva provokes corneal lesions. Therefore, a chondromucosal graft is obligatory. This research has been performed in 20 albino rabbits to evaluate the possibility of tarsal plate reconstruction with conchal cartilage graft without mucosa. The results of the research have demonstrated, by different histological biopsies, that the raw surface of the perichondrium is epithelized with a new conjunctiva (neoconjunctiva. These

  4. Experience with the gold weight and palpebral spring in the management of paralytic lagophthalmos.

    Science.gov (United States)

    Terzis, Julia K; Kyere, Sampson A

    2008-03-01

    The loss of the blink reflex and the ability to close the eye actively are disabling functional and aesthetic impairments common to patients with facial paralysis. Nonphysiologic (static) management techniques involve implantation of devices in the upper eyelid that mechanically aid eye closure. The most popular devices are the gold weight and the palpebral spring. The authors' experience with these devices is presented. Thirty-nine patients treated for paralytic lagophthalmos by the senior author (J.K.T.) between 1987 and 2002 met the inclusion criteria. Eighteen patients received the gold weight and 21 received the palpebral spring. From standardized video records, preoperative and postoperative blink scores were calculated. Fifty-nine percent of the patients (23 of 39) were female, and the most common cause for facial paralysis [35.9 percent (14 of 39)] was extirpation of acoustic neuroma and other cerebellopontine lesions. Fifty percent of the gold weight cohort was younger than 20 years at the time of surgery, with almost 40 percent (seven of 18) younger than 10 years. In the palpebral spring group, 14.3 percent (three of 21) were younger than 20 years, with 4.8 percent (one of 21) younger than 10 years. The palpebral spring group obtained a larger postoperative mean blink score of 34.0 +/- 12.4 percent compared with the gain of 21.4 +/- 14.6 percent (p = 0.025) by the gold weight group. The gold weight and palpebral spring are both effective in restoring motion to the paretic upper eyelid, but the palpebral spring is more so despite the frequent need for revisions.

  5. Squamous cell dysplasia and carcinoma of the conjunctiva

    DEFF Research Database (Denmark)

    Ramberg, Ingvild; Heegaard, Steffen; Prause, Jan Ulrik

    2015-01-01

    %) had epithelial dysplasia, 19 (13%) had carcinoma in situ, and 29 (20%) had squamous cell carcinoma. A significantly higher proportion of men were found. The median age at diagnosis was 65 years. The risk of recurrence was 10.0% [95% confidence interval (CI): 5.0–15.0] after 1 year and 17.2% (95% CI......Purpose To investigate the epidemiology of squamous cell dysplasia and carcinoma of the conjunctiva in Denmark. Methods Review of the histopathological case reports at the Eye Pathology Institute (EPI), University of Copenhagen, and the National Danish Pathology Bank from 1980 to 2011. Information......: 10.8–23.7) after 5 years. The lesions were most often localized to the corneal limbus. In our records, one patient had a lymph node metastasis and the disease necessitated enucleation in two patients. No patients had died from squamous cell carcinoma of the conjunctiva. Conclusion Overall, our data...

  6. A Rare Case of Amyloidosis of the Eyelid and Conjunctiva

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    Zaria Ali

    2016-01-01

    Full Text Available Amyloidosis of the eyelid is uncommon and is typically associated with systemic associations. In contrast, amyloidosis of the conjunctiva is often localised with no other associations. We present a rare case of a 92-year-old gentleman with both cutaneous lid lesions and conjunctival amyloid with no systemic involvement. Biopsy demonstrated the hallmarks of amyloid and treatment has remained conservative. He remains at the department to be monitored for secondary glaucoma.

  7. Estudo comparativo das medidas manual e digital da fenda palpebral A comparative study of the manual and digital measurements of the palpebral fissure

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    Tânia Pereira Nunes

    2005-12-01

    Full Text Available OBJETIVO: Comparar a medida manual do comprimento vertical da fenda palpebral e sua medida obtida por meio de processamento computadorizado de imagens de indivíduos sem alterações palpebrais. MÉTODOS: Foram analisadas 102 fendas palpebrais de 51 indivíduos normais. A faixa etária variou entre 17 e 84 anos, sendo 25 (49% do sexo masculino e 26 (51% do sexo feminino. RESULTADOS: Não houve diferença estatisticamente significativa entre as medidas manuais da fenda palpebral e as obtidas por meio de processamento computadorizado de imagens. Também não se observou diferença entre ambos os sexos e a faixa etária. CONCLUSÕES: Os resultados obtidos com estes dois métodos podem ser comparados entre si devida à equivalência estatística das medidas.PURPOSE: To compare the measurement of the palpebral fissure done either manually and by computer analysis of image of individuals without lid alterations. METHODS: One hundred two palpebral fissures from 51 normal subjects have been analyzed. The patients' age ranged from 17 to 84 years, with 25 (49% males and 26 (51% females. RESULTS: There was no statistically significant difference between the measurements done either manually or by computer analysis of images, neither, when we grouped the patients by sex or age. Also we did not observe difference between males and females, and regarding age. CONCLUSIONS: The results obtained by both methods are comparable and reliable due to the statistical equivalence of the obtained measurements.

  8. Microcirculation changes of bulbar conjunctiva at primary pterygium

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    A. V. Petrayevsky

    2014-07-01

    Full Text Available Purpose. To reveal microcirculation changes in nasal part of bulbar conjunctiva at various stages of primary pterygium formation using fluorescent angiography.Methods. 10 eyes (10 patients with pinguecula, 15 eyes (14 patients with primary pterygium were investigated. As a control group 10 eyes (10 patients without pathological changes in nasal part of conjunctiva were investigated. Biomicroscopy and anterior segment fluorescent angiography were performed for all patients.Results. Severe changes of microcirculation in nasal part of conjunctiva in patients with pinguecula and pterygium were revealed in comparison with a control group. The defect of terminal limbal arcades confirmed by fluorescent angiography can be a sign of transformation of pinguecula into pterygium. Primary pterygium gets blood supply from posterior conjunctival arteries, capillary network of a semilunar fold and also from returnable branches of anterior ciliary arteries. Neovascularization going from a semilunar fold to a body of pterygium is one of possible components in pathogenesis of pterygium.Conclusion. The obtained data testify about sign of transformation of pinguecula into pterygium, blood supply sources of pterygium and a role of neogenic vessels from a capillary network of a semilunar fold in pathogenesis of this disease.

  9. Simulations of the Microcirculation in the Human Conjunctiva

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    Dow, William; Jacobitz, Frank; Chen, Peter

    2012-11-01

    The microcirculation in the conjunctiva of a healthy human subject is analyzed using a simulation approach. A comparison between healthy and diseased states may lead to early diagnosis for a variety of vascular related disorders. Previous work suggests that hypertension, arteriosclerosis, and diabetes mellitus have noticeable very early changes in the microvasculature (Davis and Landau, 1957; Ditzel, 1968; Kunitomo, 1974) and the vessels of the conjunctiva are specifically useful for this research because they can be studied non-invasively. The microcirculation in the conjunctiva has been documented over the course of disease treatments, providing both still images and video footage for information on vessel length, diameter, and connectivity as well as the direction of blood flow. The numerical method is based on a Hagen-Poiseuille balance in the microvessels and a sparse matrix solver is used to obtain the solution. The simulations use realistic vessel topology for the microvasculature, reconstructed from microscope images of tissue samples, and consider blood rheology as well as passive and active vessel properties.

  10. Mucoepidermoid carcinoma of the conjunctiva with lung metastasis

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    Pukhraj Rishi

    2015-01-01

    Full Text Available A 36-year-old lady presented with redness and decreased vision in right eye since 6 months. She was earlier diagnosed of cavitary lung lesion, presumed secondary to tuberculosis and treated with anti-tubercular treatment for 4 months. Examination of affected right eye revealed nil light perception, conjunctival congestion with an exuberant mass in the inferotemporal bulbar conjunctiva, proptosis, iris neovascularization, 360° closed angles, intraocular pressure of 48 mm Hg, exudative retinal detachment, uveal mass and orbital extension. A diagnostic needle biopsy of uveal mass revealed malignant cells. Computed tomography-guided lung biopsy revealed squamous cell carcinoma (SCC, indicating metastatic spread from the orbit. She underwent lid-sparing exenteration of the right eye. Histopathological examination of the orbital tissue revealed mucoepidermoid carcinoma arising from the conjunctiva with extensive invasion into the orbital tissue, muscle fibers, sclera, choroid and optic nerve. Multiple tumor emboli were seen in the lumen of orbital blood vessels. In conclusion, mucoepidermoid carcinoma of the conjunctiva is a rare, aggressive variant of SCC. Early intervention is essential to prevent intraocular invasion and systemic metastasis.

  11. [Characterization of epithelial primary culture from human conjunctiva].

    Science.gov (United States)

    Rivas, L; Blázquez, A; Muñoz-Negrete, F J; López, S; Rebolleda, G; Domínguez, F; Pérez-Esteban, A

    2014-01-01

    To evaluate primary cultures from human conjunctiva supplemented with fetal bovine serum, autologous serum, and platelet-rich autologous serum, over human amniotic membrane and lens anterior capsules. One-hundred and forty-eight human conjunctiva explants were cultured in CnT50(®) supplemented with 1, 2.5, 5 and 10% fetal bovine serum, autologous serum and platelet-rich autologous serum. Conjunctival samples were incubated at 37°C, 5% CO2 and 95% HR, for 3 weeks. The typical phenotype corresponding to conjunctival epithelial cells was present in all primary cultures. Conjunctival cultures had MUC5AC-positive secretory cells, K19-positive conjunctival cells, and MUC4-positive non-secretory conjunctival cells, but were not corneal phenotype (cytokeratin K3-negative) and fibroblasts (CD90-negative). Conjunctiva epithelial progenitor cells were preserved in all cultures; thus, a cell culture in CnT50(®) supplemented with 1 to 5% autologous serum over human amniotic membrane can provide better information of epithelial cell differentiation for the conjunctival surface reconstruction. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  12. Nevo palpebral dividido - "kissing nevus": relato clínico-patológico e tratamento cirúrgico de três casos Divided nevus of the eyelid - kissing nevus: clinicopathological report and surgical treatment of three cases

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    Eduardo Ferrari Marback

    2002-03-01

    Full Text Available Objetivo: Relatar aspectos clínico-patológicos e tratamento cirúrgico em três casos de nevo palpebral dividido -"kissing nevus". Métodos: Revisão dos prontuários de três pacientes portadores de nevo palpebral dividido. Análise dos aspectos clínico-patológicos, das técnicas cirúrgicas e resultados do tratamento. Resultados: A cura das lesões com bom resultado estético e funcional foi conseguida em todos os casos. Conclusões: A exérese do nevo palpebral dividido, em mais de um tempo cirúrgico utilizando deslizamento de retalhos cutâneos palpebrais e, em um caso, transplante de pele da pálpebra superior contralateral foi curativa nos três casos estudados.Purpose: To describe the clinical and pathological aspects, surgical treatment and results of three cases of divided nevus -"kissing nevus"- of the eyelid. Methods: Review of the clinicopathological data and surgical techniques used to treat these patients. Results: Cure of the lesions with good esthetic and functional results were obtained in all cases. Conclusions: Surgical excision of the divided nevus of the eyelid in more than one surgical session using flaps from the adjacent skin, and in one case, a free skin graft from the contralateral superior lid, was curative in the studied three cases.

  13. Surgical procedure for limbal dermoid and palpebral coloboma-dermoid in English bulldog puppy

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    Božinović Stanko

    2009-01-01

    Full Text Available A dermoid is a malformation, a congenital choristoma, in fact an ectopic part of the skin. This malformation can be located on the eyelids (palpebral, on the palpebral or bulbar part of the conjunctive, on the third eyelid or on the cornea, the limbus edge of the eyelid. Ocular dermoids consist of a cornified squamous-stratified epithelium that can be pigmented to various degrees, located on irregular dermis in which there are hair follicles, sweat and fat glands, and, in rare cases, cartilage and bone can also be observed. Corneal dermoids can be classified into three types: limbal or epibulbar dermoid, a dermoid which covers the greater part or the entire cornea, a dermoid that covers the entire front segment of the eye. Coloboma presents a congenital malformation that is characterized by the absence of an eyelid and it can be located on the upper or on the lower lid. This paper presents the case of an English bulldog puppy in which a limbal dermoid and a palpebral coloboma-dermoid were observed at the same time. In this case, superficial keratectomy was selected for the treatment of the limbal dermoid, while the palpebral colobomadermoid was treated using excision with a plastic reconstruction procedure. A microscopic examination of sample tissue of the corneal demoid showed, on the surface, cornified squamous-stratified epithelium lying on the dermis. The dermis was observed to contain hair follicles, as well as sweat and fat glands.

  14. Swollen eyelid reveals multiple intracranial hydatid cysts associated with a palpebral cyst.

    Science.gov (United States)

    Tzili, N; Ahbeddou, S; Ahmimech, J; Abboud, H; Boutarbouch, M; El Hassan, A; Berraho, A

    2016-02-01

    We report a case of a hydatid cyst of the eyelid in a 12-year-old boy associated with cerebral involvement. The patient was initially treated by neurosurgeons for brain cysts. The course after an interval of two months was marked by regression of the palpebral cyst on albendazole.

  15. Transposição da rima palpebral em ptose miogênica mitocondrial Tarsal switch levator for mitochondrial myogenic ptosis

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    Lucia Miriam Dumont Lucci

    2009-04-01

    Full Text Available OBJETIVO: Relatar o uso da ressecção do tarso da pálpebra superior e enxerto na pálpebra inferior para a elevação da rima palpebral e liberação do eixo visual, sem causar complicações corneanas em pacientes portadores de ptose miogênica mitocondrial. MÉTODOS: Estudo prospectivo. A técnica cirúrgica consiste na tarsectomia da pálpebra superior e autoenxerto do tarso na lamela posterior da pálpebra inferior. As cirurgias foram realizadas sob anestesia local. No caso de diplopia, a cirurgia foi realizada em apenas um olho. RESULTADOS: O procedimento foi realizado em 9 olhos de 6 pacientes com miopatia mitocondrial. Cinco pacientes eram do sexo feminino, a média de idade foi de 59,8 anos e o seguimento variou de 30 a 60 meses. A rima palpebral elevou em todos os pacientes, descobrindo o eixo visual na posição primária do olhar e melhorando a posição viciosa de cabeça. Não houve complicações decorrentes da exposição do globo ocular. CONCLUSÃO: A técnica de transposição da rima palpebral é útil na correção do mau posicionamento das pálpebras em pacientes sem mecanismos de proteção porque eleva a pálpebra superior e a inferior, diminuindo ou eliminando o risco de causar lagoftalmo com complicações corneanas.PURPOSE: To report the use of tarsal switch levator resection procedures that lift the palpebral fissure to visual axis without causing corneal complications in patients with mitochondrial myogenic ptosis. METHODS: Prospective study. The technique consists of an upper eyelid tarsectomy, with transfer of the autologous tarsoconjunctival graft to the posterior lamella of the lower eyelid. The surgeries were performed under local anesthesia. In case of diplopia, the surgery was performed in one eye. RESULTS: Tarsal switch procedure was performed in 9 eyes of 6 patients with mitochondrial myopathy. There were 5 women; the average age was 59.8 years and the follow-up ranged from 30 to 60 months. The palpebral

  16. Ultrasound biomicroscopy as a tool for conjunctiva and eyelids evaluation

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    V. N. Trubilin

    2015-01-01

    Full Text Available Currently, ultrasound biomicroscopy (UBM is the only diagnostic method that uses a 50‑100 MHz transducer with a depth of penetration of 4 mm. This provides greater sensitivity and resolution.Aim. To visualize meibomian glands and to evaluate their morphological and functional status using UBM.Methods. UBM was performed in 14 patients aged 29‑81 with obvious meibomian gland dysfunction (MGD and healthy meibomian glands. 6 patients had no biomicroscopic signs of blepharitis while 8 patients had biomicroscopic signs of blepharitis, blepharoconjunctivitis, and MGD.Results. UBM provides detailed information on meibomian glands and eyelid margins and their pathological conditions, i.e., eyelid margin thickening due to inflammation, meibomian gland orifice obstruction, increase in distance between meibomian glands due to their atrophy, and cartilaginous tissue destruction. UBM findings may depend on patient age as well as on disease stage and severity. When re-positioning UBM transducer, bullous conjunctiva and subconjunctival cysts can be visualized. This provides differential diagnosis between opaque cysts and tumors.Conclusion. UBM combined with standard exams increases information value, reliability, and accuracy of the diagnostics of anterior segment disorders and facilitates the development of targeted therapeutic approaches. Further studies on diagnostic value of conjunctiva and eyelids UBM are required.

  17. Ocular allergic inflammation: interaction between the cornea and conjunctiva.

    Science.gov (United States)

    Fukuda, Ken; Nishida, Teruo

    2010-11-01

    Severe ocular allergic diseases such as vernal keratoconjunctivitis are characterized not only by conjunctival allergic inflammation, including infiltration of T helper 2 cells and eosinophils into the conjunctiva, but also by various corneal disorders such as persistent epithelial defects and shield ulcer. Although the cornea and conjunctiva are thought to influence each other during ocular allergic inflammation, direct evidence for interaction between these tissues in vivo has been lacking. Eosinophils and eosinophil-derived factors are implicated in the pathogenesis of corneal lesions associated with ocular allergy, with cytotoxic granule proteins such as major basic protein and matrix metalloproteinase 9 derived from eosinophils having been detected in shield ulcer. Major basic protein exhibits cytotoxic effects in cultured corneal epithelial cells and inhibits corneal epithelial wound healing in organ culture, whereas matrix metalloproteinase 9 can degrade the corneal epithelial basement membrane. In vitro studies have revealed that cytokines and other inflammatory mediators directly impair the barrier function of corneal epithelial cells and increase the expression of chemokines and adhesion molecules by corneal stromal fibroblasts, effects that may enhance allergic inflammation. We have recently shown that removal of the corneal epithelium augmented late-phase clinical signs and conjunctival eosinophilia, whereas conjunctival inflammation delayed corneal epithelial wound healing, in a rat model of ocular allergy. Conjunctival allergic inflammation and corneal epithelial disorders thus interact with each other in vivo to generate a vicious cycle, interruption of which might provide the basis for novel approaches to the treatment of severe ocular allergy.

  18. Ptose palpebral associada a paquidermoperiostose: relato de caso Eyelid ptosis associated with pachydermoperiostosis: case report

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    Ana Paula Ximenes Alves

    2005-06-01

    Full Text Available Descreve-se caso clínico de um indivíduo acometido por paquidermoperiostose, cuja queixa principal foi ptose palpebral bilateral. Trata-se de doença hereditária, autossômica dominante, que acomete a pele, os ossos e os tecidos moles, resultando em acentuada hipertrofia tarsal. Discute-se a fisiopatologia da ptose e o tratamento executado no caso.We describe a clinical case of a patient with pachydermoperiostosis and bilateral palpebral ptosis. It is a hereditary, dominant autosomic disease, which affects skin, bones and soft tissues. In the eyelid, it causes an important tarsal hypertrophy. We discuss the physiopathology and treatment of the ptosis.

  19. Avaliação da técnica de esfoliação com escova citológica para coleta de células conjuntivais em gatos sadios: comparação entre a face palpebral da membrana nictitante e a conjuntiva palpebral

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    Sonia A.S. Venancio

    2012-11-01

    Full Text Available A citologia conjuntival é um importante meio de diagnóstico de afecções da superfície ocular. Buscam-se técnicas que forneçam quantidade e qualidade celular, com uso de instrumentos que provoquem mínimo trauma e que diminuam as chances de danos iatrogênicos ao olho. Existem diversas técnicas de coleta de células, entre elas encontram-se: impressão, esfoliação e punção por agulha fina. Dentre os métodos utilizados para esfoliação, o uso da escova citológica fornece resultados superiores em vários parâmetros, incluindo a qualidade das células. Estudou-se a citologia conjuntival por esfoliação com escova citológica, utilizada para coleta de material da cérvix uterina, tendo como objetivos determinar se tal instrumento se adequaria à coleta de material da face palpebral da membrana nictitante e da conjuntiva palpebral de felinos sadios. Foram avaliados os seguintes parâmetros: facilidade de execução da técnica, possibilidade de ocorrência de danos iatrogênicos e quantidade e qualidade de células coletadas. Cinquenta gatos machos (58% e fêmeas (42%, com ou sem raça definida, participaram do estudo. Apenas gatos isentos de alterações oculares no exame físico foram incluídos. A escova citológica se mostrou um instrumento de fácil utilização, que fornece células em quantidade satisfatória e com morfologia preservada. Comparada a conjuntiva palpebral, a face palpebral da membrana nictitante se mostrou um local mais adequado à realização da coleta de amostras citológicas, pela maior facilidade de execução da técnica e menor possibilidade de danos iatrogênicos. No que diz respeito à quantidade e qualidade celular, não houve diferença significativa entre os dois locais de coleta. Foi possível observar células provenientes das diferentes camadas do epitélio conjuntival com predomínio de células intermediárias e ausência de células caliciformes.

  20. Lesão palpebral como manifestação primária do lúpus eritematoso discóide

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    Juliana Grilo Teles

    2013-02-01

    Full Text Available O lúpus eritematoso discóide é uma desordem autoimune que geralmente afeta áreas da pele expostas ao sol. A apresentação de lesões palpebrais na ausência de outras anormalidades cutâneas é incomum, sendo o envolvimento da pálpebra inferior prevalente em apenas 6% dos pacientes com lúpus eritematoso cutâneo crônico. Relatamos o caso de uma paciente do sexo feminino de 40 anos, com hiperemia, madarose e ulceração na pálpebra inferior do olho esquerdo refratária ao tratamento para blefarite. Inicialmente, outra lesão semelhante havia sido descrita na pálpebra superior do olho direito. No entanto, as biópsias incisionais mostraram-se inconclusivas. Diante de uma lesão migratória palpebral de características semelhantes à primeira, a hipótese clínica de lúpus eritematoso discóide foi aventada e o diagnóstico confirmado por meio de revisão histopatológica. Uma forte suspeita clínica e o reconhecimento precoce podem evitar erros diagnósticos, complicações clínicas e tratamentos inapropriados, como descrito neste caso de lesão palpebral como manifestação primária do lúpus eritematoso discóide.

  1. Detection of specific Mycoplasma conjunctivae antibodies in the sera of sheep with infectious keratoconjunctivitis.

    Science.gov (United States)

    Belloy, L; Giacometti, M; Abdo, E M; Nicolet, J; Krawinkler, M; Janovsky, M; Bruderer, U; Frey, J

    2001-01-01

    The serological cross reactions between Mycoplasma conjunctivae, the etiological agent of infectious keratoconjunctivitis (IKC), and the antigenetically and phylogenetically closely related Mycoplasma ovipneumoniae, which is often found in sheep, were analysed. Cross reacting antigens were identified using sera from sheep with IKC and from sheep of herds known to be free of IKC, as well as rabbit hyperimmune serum specific to the two Mycoplasma species. Cross reactions were predominantly due to the strongly antigenic proteins of 42 kDa and 83 kDa. Serospecific antigens of M. conjunctivae could be separated from cross-reacting antigens by the extraction of Tween 20-soluble membrane proteins. The Tween 20-extracted proteins of the M. conjunctivae strain HRC/581T were used for the development of an indirect ELISA test. This ELISA test was shown to be a useful serological method for the diagnosis of M. conjunctivae infections and to identify infected sheep herds.

  2. Determination of Structural and Morphological Parameters of Human Bulbar Conjunctiva from Optical Diffuse Reflectance Spectra

    Science.gov (United States)

    Lisenko, S. A.; Firago, V. A.; Kugeiko, M. M.; Kubarko, A. I.

    2016-09-01

    We have developed a method for on-the-fl y retrieval of the volume concentration of blood vessels, the average diameter of the blood vessels, the blood oxygenation level, and the molar concentrations of chromophores in the bulbar conjunctiva from its diffuse reflectance spectra, measured when the radiation delivery and detection channels are spatially separated. The relationship between the diffuse reflectance spectrum of the conjunctiva and its unknown parameters is described in terms of an analytical model, constructed on the basis of a highly accurate approximation analog of the Monte Carlo method. We have studied the effect of localization of hemoglobin in erythrocytes and localization of erythrocytes in the blood vessels on the power of the retrieval of structural and morphological parameters for the conjunctiva. We developed a device for obtaining video images of the conjunctiva and contactless measurements of its diffuse reflectance spectrum. By comparing simulated diffuse reflectance spectra of the conjunctiva with the experimental measurements, we established a set of chromophores which must be taken into account in the model for reproducing the experimental data within the measurement error. We observed absorption bands for neuroglobin in the experimental spectra, and provided a theoretical basis for the possibility of determining its absolute concentrations in the conjunctiva. We have shown that our method can detect low bilirubin concentrations in blood.

  3. Corrección de ptosis palpebral por la incisión de blefaroplastia Upper eyelid ptosis treatment using blepharoplasty incision

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    A. Novo Torres

    2006-09-01

    Full Text Available Se entiende por blefaroptosis el nivel anormalmente bajo del párpado superior durante la mirada directa. Los mejores resultados se obtienen con las técnicas de resección o avance del músculo elevador o su aponeurosis, siempre que el elevador posea una función adecuada. Nuestra intención es presentar una modificación a la técnica de Blaskovics para la corrección de blefaroptosis moderadas, con buena función del elevador Presentamos una serie de 10 casos donde se utilizó una variante de la operación de Blaskovics de resección del elevador para la corrección quirúrgica de la ptosis palpebral. De los 10 casos, 7 fueron bilaterales y 3 unilaterales. En todos ellos la función del elevador se situaba entre 4 y 8 mm y el grado de ptosis fue mayor de 4 mm con disminución del campo visual en la mirada directa. La técnica quirúrgica incluyó un abordaje cutáneo mediante la incisión horizontal de Blefaroplastia superior, la exposición amplia del músculo elevador y su aponeurosis, respetando las bolsas grasas orbiculares y separándolo de la conjuntiva palpebral. En todos los casos se obtuvo corrección de las ptosis. El grado de asimetría fue inferior a 0,3 cm. Un caso presentó en el postoperatorio inmediato dehiscencia de la sutura en su lado medial y tuvo que ser reintervenido a los 10 días. El edema palpebral postoperatorio se resolvió a partir del 2º día postoperatorio desapareciendo hacia el día 8º y permitiendo una valoración fiable en dicha fecha. El grado de satisfacción de los paciente fue bueno o muy bueno y el campo visual fue completo en todos los pacientes Las técnicas clásicas y sus modificaciones para la corrección de los casos de ptosis siguen teniendo validez. Con esta modificación que respeta la conjuntiva palpebral ocular se evita añadir morbilidad al proceso quirúrgico. Pensamos que la integridad de la conjuntiva redunda en un mayor confort postoperatorio al paciente, disminuye el edema conjuntival

  4. Paucibacterial Microbiome and Resident DNA Virome of the Healthy Conjunctiva

    Science.gov (United States)

    Doan, Thuy; Akileswaran, Lakshmi; Andersen, Dallin; Johnson, Benjamin; Ko, Narae; Shrestha, Angira; Shestopalov, Valery; Lee, Cecilia S.; Lee, Aaron Y.; Van Gelder, Russell N.

    2016-01-01

    Purpose To characterize the ocular surface microbiome of healthy volunteers using a combination of microbial culture and high-throughput DNA sequencing techniques. Methods Conjunctival swab samples from 107 healthy volunteers were analyzed by bacterial culture, 16S rDNA gene deep sequencing (n = 89), and biome representational in silico karyotyping (BRiSK; n = 80). Swab samples of the facial skin (n = 42), buccal mucosa (n = 50), and environmental controls (n = 27) were processed in parallel. 16S rDNA gene quantitative PCR was used to calculate the bacterial load in each site. Bacteria were characterized by site using principal coordinate analysis of metagenomics data. BRiSK data were analyzed for presence of fungi and viruses. Results Corynebacteria, Propionibacteria, and coagulase-negative Staphylococci were the predominant organisms identified by all three techniques. Quantitative 16S PCR demonstrated approximately 0.1 bacterial 16S rDNA/human actin copy on the ocular surface compared with greater than 10 16S rDNA/human actin copy for facial skin or the buccal mucosa. The conjunctival bacterial community structure is distinct compared with the facial skin (R = 0.474, analysis of similarities P = 0.0001), the buccal mucosa (R = 0.893, P = 0.0001), and environmental control samples (R = 0.536, P = 0.0001). 16S metagenomics revealed substantially more bacterial diversity on the ocular surface than other techniques, which appears to be artifactual. BRiSK revealed presence of torque teno virus (TTV) on the healthy ocular surface, which was confirmed by direct PCR to be present in 65% of all conjunctiva samples tested. Conclusions Relative to adjacent skin or other mucosa, healthy ocular surface microbiome is paucibacterial. Its flora are distinct from adjacent skin. Torque teno virus is a frequent constituent of the ocular surface microbiome. (ClinicalTrials.gov number, NCT02298881.) PMID:27699405

  5. Evaluation of palpebral fissure and orbital volume after bimatoprost 0.03% orbital injections. Experimental study in rats

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    Nilson Lopes da Fonseca Junior

    2014-12-01

    Full Text Available Objective: To evaluate in experimental animals the changes of the palpebral fissure and the orbital volume after orbital injection of bimatoprost 0.03%. Methods: Two main groups of Wistar rats were analyzed, one after orbital injection of bimatoprost 0.03% and another, a control group, after orbital injection of saline solution. The calculation of the palpebral fissure was done on images by means of computer processing, using the program Image J. After taking photographs, the animals were submitted to bilateral orbital exenteration and the volume was calculated in all the animals by the water displacement method (Archimedes’ Principle. Results: While comparing the measurements of the palpebral fissure and the orbital volume among animals given an injection with bimatoprost 0.03% and the control group it was found that there were no statistically significant differences. Conclusions: In this study there were no statistically significant differences in the measurement of the vertical palpebral fissure and the orbital volume among animals given the orbital injection of bimatoprost 0.03% and the animals of the control group.

  6. Reanimación palpebral con colgajo frontal miofuncional: Caso clínico

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    F. García-García; A. Cárdenas-Mejía

    2014-01-01

    El párpado es una estructura crítica para la protección y función del globo ocular, y parte primordial en la estética facial. Su reconstrucción está determinada por la extensión de la lesión y el compromiso de las diferentes capas. Siempre se preferirán tejidos loco-regionales debido a su mayor similitud y disposición. Los métodos de reanimación palpebral se pueden dividir en estáticos y dinámicos, considerando a estos últimos como el único medio para restaurar el parpadeo. Presentamos un cas...

  7. First report of Mycoplasma conjunctivae from wild Caprinae with infectious keratoconjunctivitis in the Pyrenees (NE Spain).

    Science.gov (United States)

    Marco, Ignasi; Mentaberre, Gregorio; Ballesteros, Cristina; Bischof, Daniela F; Lavín, Santiago; Vilei, Edy M

    2009-01-01

    Frequent outbreaks of infectious keratoconjunctivitis have been reported in wild Caprinae in Europe. While etiologic studies in the Alps indicate that the main etiologic agent is Mycoplasma conjunctivae, there are few reports from other mountain areas, such as the Pyrenees, where M. conjunctivae has never been reported. In 2006 and 2007, five adult Pyrenean chamois (Rupicapra pyrenaica; two males and three females) and one adult male European mouflon (Ovis orientalis musimon) were studied; they exhibited clinical symptoms of infectious keratoconjunctivitis such as blindness, corneal opacity, and ulceration. In three of the five chamois tested, and in the mouflon, Mycoplasma conjunctivae was identified from conjunctival swabs by means of a TaqMan(R) polymerase chain reaction based on the lipoprotein gene lppS. Cluster analysis indicated that the three southern chamois isolates form a cluster that is distinct from the mouflon isolate. This is the first report of M. conjunctivae in Pyrenean chamois, and it supports the hypothesis that M. conjunctivae also could be the main cause of infectious keratoconjunctivitis in areas other than the Alps, such as the Pyrenees.

  8. Immune responses to Mycoplasma conjunctivae in alpine ibex, alpine chamois, and domestic sheep in Switzerland.

    Science.gov (United States)

    Degiorgis, M P; Abdo, E M; Nicolet, J; Frey, J; Mayer, D; Giacometti, M

    2000-04-01

    The humoral immune response of three alpine chamois (Rupicapra rupicapra rupicapra), two alpine ibex (Capra ibex ibex) and three domestic sheep naturally affected with infectious keratoconjunctivitis (IKC), and four ibex and two sheep experimentally infected with Mycoplasma conjunctivae was analysed. In addition, the local immune response to M. conjunctivae was analysed using conjunctival washes from chamois and sheep. Immunoblot analysis of sera using whole cell antigens of M. conjunctivae revealed the major immunogenic proteins which had molecular masses of 175, 83, 68, 60, 50, 42, 36, and 33 kDa. Major antigens were found at 83, 68, 60, and 42 kDa in both sera and conjunctival washes from naturally infected animals of all three Caprinae species. In experimentally infected animals, antibodies to the 68 and 60 kDa antigens were dominant. Naturally infected animals showed much stronger immune reactions than those experimentally infected, and specific antibodies appeared 2 to 4 wk after experimental infection. To evaluate possible cross-reactions, whole cell antigen of M. conjunctivae was analysed by immunoblot against hyperimmune sera of closely related Mycoplasma spp. Antibodies to the 175, 73, 68, 60, and 33 kDa antigens appeared to be specific to M. conjunctivae. Cross-reactions mainly with 83, 50, and 42 kDa antigens were detected, in particular with M. ovipneumoniae and M. bovoculi hyperimmune sera, but also with antisera against M. capricolum capricolum and M. putrefaciens.

  9. A new bovine conjunctiva model shows that Listeria monocytogenes invasion is associated with lysozyme resistance.

    Science.gov (United States)

    Warren, Jessica; Owen, A Rhys; Glanvill, Amy; Francis, Asher; Maboni, Grazieli; Nova, Rodrigo J; Wapenaar, Wendela; Rees, Catherine; Tötemeyer, Sabine

    2015-08-31

    Listerial keratoconjunctivitis ('silage eye') is a wide spread problem in ruminants causing economic losses to farmers and impacts negatively on animal welfare. It results from direct entry of Listeria monocytogenes into the eye, often following consumption of contaminated silage. An isolation protocol for bovine conjunctival swabbing was developed and used to sample both infected and healthy eyes bovine eyes (n=46). L. monocytogenes was only isolated from one healthy eye sample, and suggests that this organism can be present without causing disease. To initiate a study of this disease, an infection model was developed using isolated conjunctiva explants obtained from cattle eyes post slaughter. Conjunctiva were cultured and infected for 20 h with a range of L. monocytogenes isolates (n=11), including the healthy bovine eye isolate and also strains isolated from other bovine sources, such as milk or clinical infections. Two L. monocytogenes isolates (one from a healthy eye and one from a cattle abortion) were markedly less able to invade conjunctiva explants, but one of those was able to efficiently infect Caco2 cells indicating that it was fully virulent. These two isolates were also significantly more sensitive to lysozyme compared to most other isolates tested, suggesting that lysozyme resistance is an important factor when infecting bovine conjunctiva. In conclusion, we present the first bovine conjunctiva explant model for infection studies and demonstrate that clinical L. monocytogenes isolates from cases of bovine keratoconjunctivitis are able to infect these tissues.

  10. Determining the Depth of Injury in Bioengineered Tissue Models of Cornea and Conjunctiva for the Prediction of All Three Ocular GHS Categories.

    Directory of Open Access Journals (Sweden)

    Michaela Zorn-Kruppa

    Full Text Available The depth of injury (DOI is a mechanistic correlate to the ocular irritation response. Attempts to quantitatively determine the DOI in alternative tests have been limited to ex vivo animal eyes by fluorescent staining for biomarkers of cell death and viability in histological cross sections. It was the purpose of this study to assess whether DOI could also be measured by means of cell viability detected by the MTT assay using 3-dimensional (3D reconstructed models of cornea and conjunctiva. The formazan-free area of metabolically inactive cells in the tissue after topical substance application is used as the visible correlate of the DOI. Areas of metabolically active or inactive cells are quantitatively analyzed on cryosection images with ImageJ software analysis tools. By incorporating the total tissue thickness, the relative MTT-DOI (rMTT-DOI was calculated. Using the rMTT-DOI and human reconstructed cornea equivalents, we developed a prediction model based on suitable viability cut-off values. We tested 25 chemicals that cover the whole range of eye irritation potential based on the globally harmonized system of classification and labelling of chemicals (GHS. Principally, the MTT-DOI test method allows distinguishing between the cytotoxic effects of the different chemicals in accordance with all 3 GHS categories for eye irritation. Although the prediction model is slightly over-predictive with respect to non-irritants, it promises to be highly valuable to discriminate between severe irritants (Cat. 1, and mild to moderate irritants (Cat. 2. We also tested 3D conjunctiva models with the aim to specifically address conjunctiva-damaging substances. Using the MTT-DOI method in this model delivers comparable results as the cornea model, but does not add additional information. However, the MTT-DOI method using reconstructed cornea models already provided good predictability that was superior to the already existing established in vitro/ex vivo

  11. Immunohistochemical diagnosis of malignant melanoma of the conjunctiva and uvea: comparison of the novel antibody against melan-A with S100 protein and HMB-45

    DEFF Research Database (Denmark)

    Heegaard, Steffen; Jensen, O.A.; Prause, J.U.

    2000-01-01

    ophthalmology, A103, conjunctiva, gp100, HMB-45, malignant melanoma, MART-1, melan-A, S100, uvea......ophthalmology, A103, conjunctiva, gp100, HMB-45, malignant melanoma, MART-1, melan-A, S100, uvea...

  12. Mucoepidermoid carcinoma of the bulbar conjunctiva – an interventional case report

    Directory of Open Access Journals (Sweden)

    Quintas, Ana M.

    2011-01-01

    Full Text Available Purpose: Mucoepidermoid carcinoma is a rare variant of squamous cell carcinoma of the conjunctiva. It appears more frequently in the elderly, it is more aggressive than squamous cell carcinoma, and it has a higher recurrence rate and higher incidence of intraocular and orbital invasion. Methods: We report a case of a 74-year-old man who presented to the Emergency Department with a one month history of painful red left eye. Results: The patient presented with visual acuity was 10/10 in both eyes and a conjunctiva tumor on the bulbar conjunctiva of left eye. The UBM revealed a thickening of the conjunctiva-sclera complex with no signs of intraocular invasion. A biopsy was performed and the diagnosis was of mucoepidermoid carcinoma. Two local excisions with adjuvant cryotherapy and mitomycin C aplication were carried out in a period of 6 months. After 9 months of follow-up there has not been any sign of recurrence. Conclusions: The early diagnosis and treatment of carcinoma is essential not only to prevent the intraocular spread and preserve visual function but also to prevent local or systemic recurrence and dissemination.

  13. Xenogeneic acellular conjunctiva matrix as a scaffold of tissue-engineered corneal epithelium.

    Directory of Open Access Journals (Sweden)

    Haifeng Zhao

    Full Text Available Amniotic membrane-based tissue-engineered corneal epithelium has been widely used in the reconstruction of the ocular surface. However, it often degrades too early to ensure the success of the transplanted corneal epithelium when treating patients with severe ocular surface disorders. In the present study, we investigated the preparation of xenogeneic acellular conjunctiva matrix (aCM and evaluated its efficacy and safety as a scaffold of tissue-engineered corneal epithelium. Native porcine conjunctiva was decellularized with 0.1% sodium dodecyl sulfate (SDS for 12 h at 37°C and sterilized via γ-irradiation. Compared with native conjunctiva, more than 92% of the DNA was removed, and more than 90% of the extracellular matrix components (glycosaminoglycan and collagen remained after the decellularization treatment. Compared with denuded amniotic membrane (dAM, the aCM possessed favorable optical transmittance, tensile strength, stability and biocompatibility as well as stronger resistance to degradation both in vitro and in vivo. The corneal epithelial cells seeded on aCM formed a multilayered epithelial structure and endured longer than did those on dAM. The aCM-based tissue-engineered corneal epithelium was more effective in the reconstruction of the ocular surface in rabbits with limbal stem cell deficiency. These findings support the application of xenogeneic acellular conjunctiva matrix as a scaffold for reconstructing the ocular surface.

  14. Palpebral involvement as a presenting and sole manifestation of discoid lupus erythematosus.

    Science.gov (United States)

    Yaghoobi, Reza; Feily, Amir; Behrooz, Bahar; Yaghoobi, Elena; Mokhtarzadeh, Shabnam

    2010-11-04

    A 28-year-old woman presented with a 2-year history of idiopathic, chronic blepharitis unresponsive to several courses treatment of corticosteroid eye drops. Physical examination was notable for edematous, erythematous plaques of the lower eyelids with madarosis in the absence of preceding skin scarring. Biopsy specimen was obtained and diagnosis of discoid lupus erythematosus (DLE) was made. DLE is a chronic, cutaneous disease that is clinically characterized by a malar rash, acute erythema, and discoid lesions. Localized DLE occurs when the head and neck only are affected, while widespread DLE occurs when other areas are affected, regardless of whether disease of the head and neck is seen. Patients with widespread involvement often have hematologic and serologic abnormalities, are more likely to develop systemic lupus erythematosus, and are more difficult to treat. A number of skin diseases may be confused with DLE, such as psoriasis, seborrheic dermatitis, acne, rosacea, lupus vulgaris, sarcoidosis, Bowen's disease, polymorphous light eruption, lichen planopilaris, dermatomyositis, granuloma annulare, and granuloma faciale. Palpebral lesions may rarely be the presenting or sole manifestation of the disease and lower eyelid involvement is seen in 6% of patients with chronic, cutaneous lupus erythematosus. DLE should therefore be considered as a differential diagnosis in chronic blepharitis or madarosis that persists despite usual medical management and eyelid hygiene. The patient was treated successfully with hydroxychloroquine. The skin lesions resolved with minimal scarring.

  15. Effectiveness of Piper betle leaf infusion as a palpebral skin antiseptic

    Directory of Open Access Journals (Sweden)

    Husnun Amalia

    2016-02-01

    Full Text Available The goal of an antiseptic is to eliminate or greatly reduce the number of microorganisms in the surgical field at the time of the surgery. The objective of this study was to verify the effectiveness of 20% Piper betle leaf infusion as an antiseptic solution in pre-surgery cataract patients. A clinical trial with partner-matching design was conducted on 31 pairs of eyelids. From each pair of eyelids, one eyelid was asigned to the Piper betle infusion group and the opposite one to the povidone-iodine group. The microorganisms were collected by swab from the patient’s palpebral skin, inoculated on nutrient agar, and incubated at 37oC for 20 hours. The antiseptic effectiveness was measured by counting the microbial colonies before and after administration of the antiseptic solutions. This study demonstrates that the mean colony counts after application of 20% Piper betle leaf infusion showed a significant reduction of 27-100% compared with those before administration (p=0.001. Mean colony counts after 10% povidone-iodine administration showed a significant reduction of 88-100% compared with the mean counts before the solution was applied (p=0.000. The 20% Piper betle infusion has an antiseptic potential. Nevertheless, the 10% povidone-iodine solution has more effective antiseptic capability.

  16. Ptosis Palpebral in a Urban Area named: December 5. Paez Municipality, Portuguesa State. Venezuela 2007.

    Directory of Open Access Journals (Sweden)

    Milenis López León

    2010-04-01

    Full Text Available A descriptive longitudinal prospective study was made in the Urban Area named December 5 of Páez Municipality, Portuguesa State, in The Venezuela’s Republic, including only the period since September 4 to December 11, 2007 with the objective to define the clinical epidemiological state of Ptosis Palpebral in the Region mentioned. The universe was conformed by 7000 patients of all ages, being a sample of 60 ill persons, for obtaining the information a structural interview was used made by the authors, having productiveness the use of Ophthalmology clinical backgrounds of each person; the obtaining data were introduced in a Pentium IV computer by means of EPINFO Program to calculate them. The female sex was the one that predominate, and it happens the same wit the skin colour (not white finding the ages between 21 and 41 years as high frequency. The moderate ptosis was the most usual, predominating the unilaterals and from etiological point of view: The acquires; obtaining the traumatics the highest incidence within them; resulting ametropias as the ocular pathologies more notables in studied patients and a considerable number of them were tributary of the surgical treatment even though the latest diagnostic, that´s why a previous detection is imposed of the referred entity, helping to improve your Qualitiy Life and reincorporating to your society .

  17. Effectiveness of Piper betle leaf infusion as a palpebral skin antiseptic

    Directory of Open Access Journals (Sweden)

    Husnun Amalia

    2009-08-01

    Full Text Available The goal of an antiseptic is to eliminate or greatly reduce the number of microorganisms in the surgical field at the time of the surgery. The objective of this study was to verify the effectiveness of 20% Piper betle leaf infusion as an antiseptic solution in pre-surgery cataract patients. A clinical trial with partner-matching design was conducted on 31 pairs of eyelids. From each pair of eyelids, one eyelid was asigned to the Piper betle infusion group and the opposite one to the povidone-iodine group. The microorganisms were collected by swab from the patient’s palpebral skin, inoculated on nutrient agar, and incubated at 37oC for 20 hours. The antiseptic effectiveness was measured by counting the microbial colonies before and after administration of the antiseptic solutions. This study demonstrates that the mean colony counts after application of 20% Piper betle leaf infusion showed a significant reduction of 27-100% compared with those before administration (p=0.001. Mean colony counts after 10% povidone-iodine administration showed a significant reduction of 88-100% compared with the mean counts before the solution was applied (p=0.000. The 20% Piper betle infusion has an antiseptic potential. Nevertheless, the 10% povidone-iodine solution has more effective antiseptic capability.

  18. Técnica de Crawford en el tratamiento de la ptosis palpebral congénita

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    Clara Gisela Gómez Cabrera

    Full Text Available Objetivo: evaluar los resultados quirúrgicos de la técnica de Crawford mediante el empleo de silastic y polipropileno 4.0 y las complicaciones presentadas. Métodos: se realizó un estudio descriptivo y prospectivo de 12 pacientes (16 párpados con ptosis palpebral congénita desde enero 2009 a diciembre 2010 en la consulta de Oculoplastia del Instituto Cubano de Oftalmología "Ramón Pando Ferrer". Fueron excluidos los que tenían cirugía anterior de dicha enfermedad. Resultados: el 83,3 % fueron del sexo masculino y el 91,6 % menores de 9 años de edad; de ellos, 4 casos de 0 a 2 y de 6 a 8, respectivamente; 3 casos en el grupo de 3 a 5 y solo 1 caso mayor de 9 años. El 75 % fueron ptosis congénita simple y el 56 % severas. La ptosis resultó corregida en 13 párpados para el 81 %. Con el uso de sutura polipropileno 4.0, dos párpados se encontraron hipocorregidos (12,6 % y seis corregidos (37,5 %; con silastic, un párpado quedó hipocorregido, (6,3 % y siete corregidos (43,7 %. Se presentó el 25 % de complicaciones, 3 párpados hipocorregidos y un granuloma supraciliar. Conclusiones: la ptosis resultó más frecuente en menores de 8 años del sexo masculino. Predominó la ptosis congénita simple, unilateral y severa. La técnica de Crawford resultó efectiva en la mayoría de los casos y similar con los dos materiales empleados.

  19. Avaliação da fenda palpebral após aplicação de toxina botulínica tipo A em pacientes com distonias faciais Evaluation of palpebral fissure after botulinum toxin type A injection in patients with facial dystonias

    Directory of Open Access Journals (Sweden)

    Mariana Eleonora Pereira Cunial

    2012-12-01

    Full Text Available OBJETIVO: Avaliar a medida da fenda palpebral em pacientes com blefaroespasmo essencial benigno (BEB e espasmo hemifacial (EHF após a aplicação periocular de toxina botulínica tipo A. MÉTODOS: Foram estudados pacientes portadores de BEB e EHF submetidos à injeção periocular de toxina botulínica tipo A pela técnica inner orbital de aplicação. Os pacientes foram fotografados em PPO antes da aplicação e catorze dias depois dela. A fenda palpebral foi mensurada nestas imagens por meio de processamento computadorizado de imagens, utilizando o programa ImageJ. As alterações da fenda palpebral foram observadas comparando-se as medidas obtidas no pré e pós-aplicação. RESULTADOS: Comparando-se as imagens obtidas com o programa ImageJ, houve aumento estatisticamente significante (pPURPOSE: To evaluate the measurement of palpebral fissure in patients with facial dystonias before and after periocular injection with botulinum toxin type A. METHODS: We studied patients with benign essential blepharospasm and hemifacial spasm underwent periocular injection of botulinum toxin type A by the inner orbital technique of application. Patients were photographed 14 days before and after application. The palpebral fissure was measured in these images by means of computerized image processing using the program ImageJ. The palpebral fissure changes were observed by comparing the measurements obtained before and after application. RESULTS: Comparing the images obtained with the program ImageJ, there was a statistically significant increase (p <0.001 of the palpebral fissure in 14 eyes (51,8% after the application of periocular injection of botulinum toxin and the images analyzed showed no decrease of the palpebral fissure. CONCLUSION: In this study, patients with facial dystonias showed increased palpebral fissure periocular statistically significant after application of botulinum toxin type A.

  20. Cellular changes in bulbar conjunctiva and Vitamin A deficiency. Connection with clinical signs.

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    Roxana del Carmen Gómez Vilela

    2008-04-01

    Full Text Available Background: Vitamin A deficiency is followed by keratinization of the mucous membrane that covers the digestive, urinary and respiratory ways. This situation contributes to the emergence of different diseases, mainly infectious illness and elevates mortality and morbidity among children. Objective: To describe the connection between the results of conjunctiva cytology and pathological history of Vitamin A deficiency. Methods: Cross-section study, from September 2003 to March 2004. The sample consisted of 338 children of both genders between 5 and 14 years. The studied variables were: the result of conjunctiva cytology and associated symptoms and individual pathological history. Results: Only 7.4 % of the cytology’s results were normal; the rest was altered, linked to respiratory, digestive and parasitic disorders, among others. Conclusion: Early diagnosis of Vitamin A deficiency can be a prevention method for different common and frequent diseases in pediatric stages.

  1. Prevalence ofHIV seropositivity among patients with squamous cell carcinoma of the conjunctiva

    Institute of Scientific and Technical Information of China (English)

    Adesuwa I Osahon; Catherine U Ukponmwan; Odarosa M Uhunmwangho

    2011-01-01

    Objective:To determine the prevalence ofHIV seropositivity among patients with squamous cell carcinoma of the conjunctiva.Methods:All patients with clinical and histopathological confirmation of squamous cell carcinoma seen during a ten year period (July1999 to June2009) were tested for HIV (Human Immunodeficiency Virus). The number of patients with squamous cell carcinoma of the conjunctiva who areHIV positive were counted.Results:A total of thirty-three(33) eyes in thirty-two(32) patients were confirmed histopathologically to have conjunctival squamous cell carcinoma. Their ages ranged from22 years to66 years with a mean age of (38.6±11.8) years (SD). The male to female ratio was1:1.5. Twenty four (75%) of these patients wereHIV positive.Conclusions: Squamous cell carcinoma is associated with the human immunodeficiency virus and is thus a marker for the disease in Benin City, Nigeria.

  2. In Vitro Study of Inflammatory Potential and Toxicity Profile of Latanoprost, Travoprost, and Bimatoprost in Conjunctiva-Derived Epithelial Cells

    National Research Council Canada - National Science Library

    Guenoun, Jean-Marc; Baudouin, Christophe; Rat, Patrice; Pauly, Aude; Warnet, Jean-Michel; Brignole-Baudouin, Francoise

    2005-01-01

    ... Médicale, U598, Cordeliers Biomedical Institute, Paris, France. METHODS . Conjunctiva-derived cells were treated in vitro with the commercial solutions of latanoprost, travoprost, bimatoprost, prostaglandin (PG...

  3. Ação do colírio de fenilefrina 10% no posicionamento palpebral de indivíduos normais Phenylephrine 10% eye drop action in the eyelid position in healthy subjects

    Directory of Open Access Journals (Sweden)

    Tânia Pereira Nunes

    2008-10-01

    Full Text Available OBJETIVOS: Determinar a ação de uma gota do colírio de fenilefrina 10% sobre as pálpebras superior e inferior de indivíduos normais; verificar a ocorrência de alterações no posicionamento das pálpebras superior e inferior do olho contralateral, após instilação desta medicação. MÉTODOS: Estudo prospectivo observacional, do qual participaram 24 indivíduos normais, com idade entre 20 e 39 anos, submetidos à instilação de uma gota do colírio de fenilefrina 10% no fundo de saco conjuntival superior, aleatoriamente em um dos olhos. Todos os indivíduos foram filmados antes e após a instilação do colírio (3, 10, 15, 30, 45 e 60 minutos. As imagens foram submetidas ao processamento digital e editadas para análise das medidas palpebrais. Foi traçada uma linha horizontal do canto medial até o canto externo. Considerou-se a altura da pálpebra superior a distância entre o ponto mais alto da margem palpebral superior e a linha horizontal traçada. A altura palpebral inferior foi avaliada como a distância entre o ponto mais baixo da margem palpebral inferior e a referida linha. RESULTADOS: Em relação à pálpebra superior, a medida antes da instilação da fenilefrina 10% diferiu significativamente dos demais momentos (pPURPOSE: To determine the upper and lower eyelid position with a single drop of 10% phenylephrine in normal individuals and observe positional lid changes in upper and lower lids of the opposite eye. METHODS: Prospective observational study including 24 healthy subjects of both genders (age range: 20-39 yrs submitted to instillation of a single drop of 10% phenylephrine in the upper fornix of one randomly chosen eye. A video camera recorded the images of both eyes before and after eye drop application at 3, 10, 15, 30, 45 and 60 minutes. The images were digitally processed and edited to analyze lid measurements (upper lid height: distance between the highest upper margin lid point and a horizontal line traced

  4. Fetal check ligament connected between the conjunctiva and the medial and lateral recti.

    Science.gov (United States)

    Osanai, Hajime; Rodríguez-Vázquez, Jose Francisco; Abe, Hiroshi; Murakami, Gen; Ohguro, Hiroshi; Fujimiya, Mineko

    2011-09-09

    There seems to be little or no information about the morphology of the fetal eye check ligament. The authors examined longitudinal and cross-histologic sections from the large collection of human fetuses at Universidad Complutense, Madrid. In longitudinal sections from 20 fetuses (four at each of 12, 15, 20, 25, and 30 weeks of gestation), a distinct connective tissue band was found connecting the medial and lateral recti and the limbus of the conjunctiva (sites at and around the lateral and medial angles of the conjunctival space). Silver impregnation revealed that the muscle endomysium (type 4 collagen dominant) was connected with composite fibers of the band (type 1 collagen). The cross-sections from three fetuses (20 weeks) exhibited a site-dependent difference in the rectus sheaths: the orbital-sided sheath suddenly increased in thickness when it tightly attached to the muscle bundles. The attaching orbital-sided muscle bundles reached 14% to 15% (or 18%-20%) in the cross-sectional area of the MR (or the LR). Taken together, the distinct connective tissue band extending to the conjunctiva was "originated from" the MR and LR rather than from a part of the muscles inserting into the connective tissue band. This band was most likely a primitive form of the check ligament. The authors hypothesize that the primitive check ligament conducts muscle tension to the conjunctiva to coordinate growth patterns between the anterior and posterior sides of the eyeball. This hypothesis may support en bloc recession for infantile esotropia.

  5. In situ carcinoma of the conjunctiva: surgical excision associated with cryotherapy

    Directory of Open Access Journals (Sweden)

    Crim N

    2013-09-01

    Full Text Available Nicolás Crim, María Elena Forniés-Paz, Rodolfo Monti, Evangelina Espósito, Juan Pablo Maccio, Julio A Urrets-Zavalía Department of Ophthalmology, University Clinic Reina Fabiola, Universidad Católica de Córdoba, Argentina Background: Although frequently underdiagnosed, squamous cell carcinoma is the most commonly observed malignancy of the conjunctiva. Multiple different treatments have been proposed to date. The purpose of this paper is to report our experience in the treatment of In situ carcinoma of the conjunctiva by surgical excision associated with cryotherapy. Methods: Four eyes in four consecutive patients (two men and two women of average age 53.2 (range 39–71 years at the time of diagnosis of ocular surface squamous neoplasia were treated by simple surgical excision and cryotherapy of the resulting surgical bed margins. In all cases, the diagnosis of in situ carcinoma was confirmed histopathologically. Results: On histopathology, the edges of the surgical specimens were free of malignant cells in three of four patients. All patients showed excellent evolution without recurrence. Mean follow-up was 6.5 (range 2–14 years. Conclusion: In situ carcinoma of the conjunctiva may be simply and successfully treated with surgical excision and cryotherapy. Keywords: conjunctival squamous cell carcinoma, surgical excision, cryotherapy

  6. Susceptibility of alpine ibex to conjunctivitis caused by inoculation of a sheep-strain of Mycoplasma conjunctivae.

    Science.gov (United States)

    Giacometti, M; Nicolet, J; Frey, J; Krawinkler, M; Meier, W; Welle, M; Johansson, K E; Degiorgis, M P

    1998-04-15

    We evaluated the susceptibility of alpine ibex (Capra ibex ibex) to mycoplasmal conjunctivitis induced by a strain of Mycoplasma conjunctivae isolated from domestic sheep by inoculation of three alpine ibexes with 1.2 x 10(6) colony forming units of M. conjunctivae in the conjunctival sac of both eyes. One more ibex was exposed to the infection by contact. Experimental animals were free of M. conjunctivae and ocular Chlamydia infection before inoculation. Conjunctivitis and serous to mucous lachrymation became apparent in all four ibexes. Clinical signs began within 2 days in inoculated animals and 22 days after the beginning of the experiment in the contact ibex. M. conjunctivae was demonstrated up to the 63th day post-inoculation by cultural and PCR-methods. After 63 days, histopathologic examination revealed nearly normal ocular tissues, and M. conjunctivae could be detected from two eyes only. No other infectious agents which might cause conjunctivitis or keratitis, including Chlamydia psittaci and Branhamella ovis, were involved. Our investigation indicates that sheep-strains of M. conjunctivae can induce conjunctivitis in alpine ibex, thus showing pathogenicity of this organism for Caprinae species other than domestic sheep and goats.

  7. Reconstrução palpebral com retalho de Fricke: relato de dois casos

    OpenAIRE

    Herzog Neto Guilherme; Sebastiá Roberto; Viana Giovanni André Pires; Machado Filipe

    2006-01-01

    O câncer de pele é o tumor mais comum na espécie humana, sendo o carcinoma basocelular o de maior prevalência. Este trabalho relata dois casos recentes deste tipo de tumor, envolvendo tanto a pálpebra superior quanto a inferior em duas mulheres. O primeiro caso é de uma mulher de 72 anos de idade, amaurótica do olho direito, com comprometimento de aproximadamente 80% da pálpebra superior esquerda, 70% da pálpebra inferior esquerda e comprometimento da parede lateral da órbita, comprovado pela...

  8. Prevalence of equine herpesvirus type 2 (EHV-2) DNA in ocular swabs and its cell tropism in equine conjunctiva.

    Science.gov (United States)

    Borchers, K; Ebert, M; Fetsch, A; Hammond, T; Sterner-Kock, A

    2006-12-20

    Equine herpes virus 2 (EHV-2), a gamma(2)-herpesvirus, is common in horses of all ages. Its role as a primary pathogen is unclear but there is an association between EHV-2, respiratory disease and keratoconjunctivitis. The purpose of this study was to gain more information on the prevalence of EHV-2 DNA in conjunctival swabs from horses with and without ocular disease and to define the anatomical site and cell type harbouring viral genome or antigen. By polymerase chain reaction (PCR) 22 out of 77 (28.6%) ocular swabs of clinically healthy and only 4 out of 48 (8.3%) samples from diseased horses were positive. To define the main virus reservoir ocular tissue from 13 randomly selected horses without pathological evidence of ocular disease were analysed by nested PCR. In two horses optic nerve, lacrimal gland and conjunctiva, in further two cases lacrimal gland and conjunctiva and in four horses the conjunctiva only were EHV-2 PCR positive. For specifying the target cell we focused on conjunctivae and selected 3 out of 15 clinically healthy slaughterhouse horses positive for EHV-2 by PCR. In situ hybridisation on sections of these paraffin embedded conjunctivae localized viral genome in histiocyte-like cells of the submucosa. Immunohistochemical staining with an EHV-2 or S100 specific polyclonal antiserum demonstrated that Langerhans cells were co-localized in the same region of the sample section where virus positive cells were detected. Furthermore, we concluded that detection of viral antigen revealed a productive virus infection.

  9. Ribosomal RNA-based analysis of the bacterial flora from the conjunctivae of cattle with bovine keratoconjunctivitis (BKC).

    Science.gov (United States)

    Hare, William R; Hoyt, Phillip G; Hohn, Christina; Higgins, James A

    2008-10-15

    Bovine keratoconjunctivitis (BKC), colloquially referred to as 'pinkeye', is a disease affecting cattle worldwide; it costs cattle producers millions of dollars in economic loss annually. While Moraxella spp. are the primary etiologic agent of pinkeye, surveys of flora from the conjunctivae of livestock from around the world have indicated that a variety of bacterial commensals occupy this niche. We used molecular biology-based methods to determine the composition of bacterial flora in the conjunctivae of normal dairy and beef cattle from Maryland (n=113), and beef cattle with clinical BKC from Louisiana (n=42). Three regimens were used: 16S rRNA PCR and DGGE analysis of amplicons; 16S rRNA PCR and cloning of amplicons into Escherichia coli followed by screening and sequencing of clones harboring inserts; and culture of bacteria on chromogenic agar followed by 16S rRNA PCR and sequencing. Most taxa were comprised of saprophytes found in the environment, such as Bacillus, Pantoea, E. coli, and Exiguobacterium. Moraxella spp. were infrequently observed. Some species, such as Propionibacterium acnes, represent taxa not previously associated with the conjunctivae. Bacillus pumilus and Bacillus licheniformis isolates from the conjunctivae of Maryland cattle were genetically distinct from isolates previously implicated in septic infections in cattle at the same location. We conclude that employing 16S rRNA-based methods for bacterial identification can be useful in defining the flora present in the conjunctivae of normal cattle, and those with BKC.

  10. [The pathogen spectrum of the conjunctiva of inhabitants of refuse disposal sites in Cairo. I].

    Science.gov (United States)

    Sixl, W; Sixl-Voigt, B; Stögerer, M; Bencko, V; Köck, M; Marth, E; Schaffler, R; Schuhmann, G; Pichler-Semmelrock, F

    1989-01-01

    In Cairo's waste disposal sites conjunctivitis is frequently found resulting from the burning process of plastic, paper, etc.. Recurrent secondary contamination of the conjunctiva by pathogenic and non-pathogenic microorganisms often takes place; however, in certain germ species, the differentiation between pathogenic or non-pathogenic organisms within a damaged mucous membrane cannot be made. Furthermore, in this study, we have attempted to investigate germ reproduction during the application of PVP-eyedrops. However, our results cannot be conclusive because of the high environmental contamination, very low personal hygiene resulting from contaminated water and the constant exposure of samples to environmental contamination. Studies will be continued.

  11. A unique case of isolated sebaceous adenoma of the bulbar conjunctiva

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    Hatice Deniz Ilhan

    Full Text Available ABSTRACT Our patient was a 34 year-old male who presented with a painless conjunctival mass that had developed 3 months before his first visit. On performing slit-lamp biomicroscopy, a lobulated pink-yellowish solid mobile mass was observed on the nasal bulbar conjunctival surface of his left eye. The tumor was excised, and histopathologic examination of the tumor revealed a sebaceous adenoma. Systemic examination was normal. No recurrence was observed during the 24-month follow-up period. Sebaceous adenoma of the bulbar conjunctiva is an extremely rare benign tumor, which may be observed to be isolated in the absence of malignancy.

  12. Triagem auditiva neonatal com emissões otoacusticas e reflexo cocleo-palpebral: estudo da sensibilidade e especificidade Newborn Hearing Screening with otoacoustic emissions and cochlear-palpebral reflex: sensitivity and specificity study

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    Rosanna Mariangela Giaffredo Angrisani

    2012-10-01

    Full Text Available OBJETIVO: analisar a especificidade e sensibilidade da TAN com emissões otoacústicas evocadas por estimulo transiente (EOAT associadas à pesquisa do reflexo cócleo-palpebral (RCP, comparando-os aos resultados do Potencial Evocado Auditivo de Tronco Encefalico (PEATE. MÉTODO: a casuística do presente estudo foi composta por 369 RN de risco para deficiência auditiva que foram submetidos à triagem com a captação das emissões otoacústicas evocadas por estímulo transiente e pesquisa do reflexo cócleo- palpebral. Os resultados foram comparados aos resultados do Potencial Evocado Auditivo de Tronco Encefalico (PEATE. RESULTADOS: a incidência do tipo da perda auditiva na população geral foi de 4RN (1,1% com perda coclear, 22 (5,9% com perda condutiva, 2 (0,5% com espectro da neuropatia auditiva (ENA, 14 (3,8% com alteração central e 15 (4,1% com atraso de maturação da via auditiva. A TAN mostrou 100% de sensibilidade e 94,6% de especificidade na detecção de alterações cocleares e espectro da neuropatia auditiva; 77,3% de sensibilidade e 94,6% de especificidade na detecção de alterações condutivas e 42,9% de sensibilidade e 94,6% de especificidade na detecção de alterações centrais. Todos os achados evidenciaram diferenças estatisticamente significantes em relação aos neonatos auditivamente normais. CONCLUSÃO: este protocolo de TAN mostrou-se eficaz na detecção de RN com alterações de cocleares e espectro da neuropatia auditiva com sensibilidade e especificidade elevadas.PURPOSE: to study the specificity and sensitivity of NHS with otoacoustic emissions transient stimulus (TEOAE associated with cochlear-palpebral reflex (CPR, and comparing the results of Auditory Evoked Potential (BAEP. METHOD: three hundred and sixty-nine neonates under risk of hearing loss were evaluated. Evaluation procedures consisted of transient otocoustic emissions(TOAEs, cochlear-palpebral reflex (CPR, and ABR diagnostic carried out in the

  13. Sealing the gap between conjunctiva and Tenon’s capsule in primary pterygium surgery

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    Ricardo Alexandre Stock

    2014-10-01

    Full Text Available Objetive: To assess the results of an alternative surgical approach in the excision of primary pterygium by analyzing the rates of recurrence and of intraoperative and postoperative complications. Methods: Retrospective cross-sectional study based reviewing the clinical records of individuals subjected to surgery for pterygium, with conjunctival autograft transplantation, fibrin glue and intraoperative application of mitomycin C. In addition, sealing was performed by suturing the gap between the conjunctiva and Tenon’s capsule. A total of 36 eyes from 35 individuals were subjected to the assessed techniques. The study variables were complications of surgery and recurrence rates during a minimun follow-up period of 6 months. Results: No recurrence occurred during the follow-up period. One graft (2.8% exhibited partial retraction, but pterygium did not recur. The intraocular pressure increased in one eye (2.8% and was controlled by clinical methods. Conclusion: Eyes in which a barrier was established between the conjunctiva and Tenon’s capsule by sealing the gap between them showed an absence of recurrence in the sample studied. However, there is the need of a random prospective study with a control group for a more accurate conclusion on the efficacy of the technique

  14. Hyperosmolarity and Benzalkonium Chloride Differently Stimulate Inflammatory Markers in Conjunctiva-Derived Epithelial Cells in vitro.

    Science.gov (United States)

    Warcoin, Elise; Clouzeau, Chloé; Roubeix, Christophe; Raveu, Anne-Laure; Godefroy, David; Riancho, Luisa; Baudouin, Christophe; Brignole-Baudouin, Françoise

    2016-12-10

    Tear hyperosmolarity is known to cause ocular surface inflammation in dry eye syndrome. Benzalkonium chloride (BAK), an eyedrop preservative, is known to induce dry eye in long-term-treated patients. Analyzing the modulation of the proinflammatory potential of hyperosmolarity in the presence of BAK on the conjunctiva could give new insights into the effect of this preservative on the disease. In a hyperosmolar model on a conjunctiva-derived cell line, and in the presence of BAK, we evaluated key inflammatory markers [CCL2, IL-8, IL-6, macrophage migration inhibitory factor (MIF) and intercellular adhesion molecule (ICAM)-1] as well as the osmoprotectant element nuclear factor of activated T cells (NFAT)5 using ELISA, RT-qPCR or immunofluorescence staining. Hyperosmolarity highly stimulated CCL2 and NFAT5 in these cells. BAK alone only increased IL-6 expression. The stress-combined condition stimulated CCL2, NFAT5, MIF and IL-8 secretion. ICAM-1 was not modulated by any of the conditions tested. In this model, hyperosmolarity and BAK induced the release of different proinflammatory mediators, and, when combined, they lead to the release of additional inflammatory cytokines. This in vitro study highlights the importance of avoiding long-term ophthalmic treatments containing BAK, as tear film hyperosmolarity can be a result of its detergent action.

  15. The Lymphatic Anatomy of the Lower Eyelid and Conjunctiva and Correlation with Postoperative Chemosis and Edema.

    Science.gov (United States)

    Shoukath, Sajna; Taylor, G Ian; Mendelson, Bryan C; Corlett, Russell J; Shayan, Ramin; Tourani, Saam S; Ashton, Mark W

    2017-03-01

    There are minimal data in the literature regarding the lymphatic drainage of the conjunctiva and lower eyelid and the relationship with postoperative chemosis and edema. Injection, microdissection, and histologic and radiologic studies were conducted on 12 hemifacial fresh cadaver specimens. Indocyanine green lymphography was conducted in five volunteers. Histology identified lymphatic vessels superficial and deep to the orbicularis oculi. Cadaveric dissection, injection, and radiographic studies identified interconnecting superficial and deep facial lymphatic systems and a conjunctival lymphatic network draining through the tarsal plate to the deep lymphatic system. The superficial lymphatic collectors traveled in subcutaneous fat within the lateral orbital and nasolabial fat compartments. The lateral deep lymphatic collectors traveled beneath orbicularis oculi, then through the superficial orbicularis retaining ligament, and into the sub-orbicularis oculi fat in the roof of the prezygomatic space. These vessels descended to preperiosteal fat at the level of zygomaticocutaneous ligaments to travel adjacent to the facial nerve into preauricular nodes. Indocyanine green lymphography identified correlating draining pathways laterally to the parotid nodes and medially to submandibular nodes. The authors have found that the lower eyelid and conjunctiva are drained by interconnecting superficial and deep lymphatic systems of the face. The superficial system is vulnerable to damage in incisions and dissection in the infraorbital area. The deep system is vulnerable to damage in dissection around the orbicularis retaining ligament and the zygomaticocutaneous ligaments. The authors suggest that concurrent damage to both the superficial and deep lymphatic systems, especially laterally, may be responsible for postoperative chemosis and edema.

  16. Uso de peso de ouro palpebral para correção do lagoftalmo em pacientes com paralisia facial Eyelid gold weight for treatment of lagophthalmus in patients with facial palsy

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    José Ricardo Gurgel Testa

    Full Text Available Introdução: O lagoftalmo decorrente da paralisia facial periférica deve ser corrigido a fim de se evitar complicações oculares. O uso de implantes de ouro como uma alternativa à tarsorrafia vem sendo estudado, mostrando bons resultados. Objetivo: O objetivo deste trabalho foi estudar os efeitos da implantação de peso de ouro em pálpebra superior para correção do lagoftalmo. Forma de estudo: clínico retrospectivo não randomizado. Material e método: Foram estudados retrospectivamente durante seis anos 59 pacientes com lagoftalmo secundário à paralisia facial de diversas etiologias e que foram submetidos à colocação de peso de ouro palpebral. Resultados: Em todos os pacientes foi consegui-do o fechamento ocular completo. As complicações do procedimento foram raras e incluíram a extrusão do peso em 8,5% dos pacientes e infecção em 5%. O tempo de permanência do peso variou de 6 meses a 6 anos, tendo sido removido em 20,3% por melhora da paralisia facial periférica. Discussão: Vários métodos têm sido utilizados para promover a proteção ocular nos casos de paralisia facial com graus variáveis de sucesso e aceitação pelo paciente. O implante de peso de ouro em pálpebra superior é um método simples, de fácil reversão e com bom resultado estético. O tempo de permanência do peso palpebral é variável na literatura e as complicações do procedimento são raras. Conclusão: O uso do peso de ouro palpebral em pacientes com paralisia facial traz bons resultados na correção do lagoftalmo e prevenção de complicações oculares.Introduction: Lagophthalmus in facial palsy must be treated in order to avoid ocular complications. The gold weight eyelid implant as an alternative to tarsorrhaphy has been studied with good results. Aim: The purpose of this report is to study the effects of the gold weight eyelid implants for treatment of lagophthalmus. Study design: clinical retrospective not randomized. Material and

  17. [Fungic microbiota of normal conjunctiva, sugar-cane and anemophilous fungi of the region of Monte Belo - Minas Gerais].

    Science.gov (United States)

    Dalfré, Joyce Treinta; Rodrigues, João Paulo Brandão; Donato, Bruno Guimarães; Giancoli Neto, Armando; de Carvalho, Juliano Lopes; de Andrade Oliveira, Daniel Iscold; Pereira, Maria Aparecida; Fiorini, João Evangelista

    2007-01-01

    To evaluate the incidence of fungi in the ocular conjunctiva of sugar-cane cutting workers as well in a sugar-cane plantation environment. Monte Belo - MG, Eye Clinic, Laboratory of Physiology and Biology of Microorganisms of Unifenas, Alfenas - MG. Swabs were made from the ocular conjunctiva of one hundred workers of both sexes and material was collected from leaves, stalk, and the environmental air from the sugar-cane plantation. These were inoculated in specific mold media. After incubation at 25 degrees C for a period of fifteen days, the plates were analyzed and colony forming units (ufc) were identified using conventional mycological techniques. Of one hundred workers involved in this research, 64 presented one or more genera of fungi, 54 (84.38%) being identified in males and 10 (15.62%) identified in females. The separation of the workers by age range showed that the prevalence of observed fungi by age was not uniform. The highest incidences were found in advanced age ranges, the increase of positivity by age being considered statistically significant (pocular conjunctiva fungus isolation (67%). The incidence was much higher in males (84.38%) as (15.62%) in females. The anemophilious fungi and those isolated from stalk and leaves were similar to those already described in the literature. The isolated filamentous fungi were much more numerous than yeast, there being some correlation between these and the conjunctiva isolates.

  18. Diplopía y ptosis palpebral izquierda como primera manifestación de metástasis hipofisarias de adenocarcinoma pulmonar Diplopia and left palpebral ptosis as a first manifestation of hypophysary metastases of pulmonary adenocarcinoma

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    S. Junquera

    2012-04-01

    Full Text Available Paciente sin antecedentes patológicos de interés que debuta con diplopía y ptosis palpebral izquierda como primera manifestación de metástasis hipofisarias de un cáncer de origen pulmonar ampliamente diseminado y no conocido previamente. El diagnóstico se hizo con pruebas de imagen específicas del área hipofisaria en donde se apreció una neoformación en silla turca, que invadía el seno cavernoso izquierdo con erosión del dorso selar, junto con la presencia de nódulos pulmonares y múltiples adenopatías, además del estudio histológico de las lesiones. Se detectó un hipogonadismo hipogonadotropo como única alteración hormonal debido a la infiltración de la hipófisis anterior por las metástasis óseas en la base del cráneo. El paciente, a pesar de recibir varias sesiones de radioterapia, sufrió un deterioro neurológico progresivo falleciendo a las pocas semanas.A patient, without significant previous medical history, who started with diplopia and left palpebral ptosis as the first manifestation of hypophysary metastases of a widely disseminated and previously undetected cancer of pulmonary origin. Together with a histological study of the lesions, the diagnosis was made with specific image tests of the hypophysary area, which detected a neoformation in the sella turca that was invading the left cavernous sinus with erosion of the verso of the sellar, together with the presence of pulmonary nodules and numerous adenopathies. An hypogonadotropic hypogonadism was detected as the only hormonal alteration due to the infiltration of the anterior hypophysis due to the osseous metastases at the base of the cranium. The patient, in spite of receiving several weeks of radiotherapy, suffered a progressive neurological deterioration and died after a few weeks.

  19. Winglets of the eye: dominant transmission of early adult pterygium of the conjunctiva.

    Science.gov (United States)

    Hecht, F; Shoptaugh, M G

    1990-06-01

    A pterygium, a wing-like thickening, of the bulbar conjunctiva is of environmental interest because it can occur on prolonged exposure to wind and weather. We describe a family with pterygium in two generations without a history of unusual exposure to the elements. There were six females and five males (including a set of male twins) with seven bilateral and four unilateral pterygia. The onset was unique in being in early adulthood, from the late teens through the twenties. This new genetic form can be distinguished by the age of onset from congenital and mid-adult pterygia, which are inherited as autosomal dominant traits. Irrespective of age, the treatment of conjunctival pterygium is surgical excision.

  20. Monitoring the conjunctiva for carbon dioxide and oxygen tensions and pH during cardiopulmonary bypass.

    Science.gov (United States)

    Weiss, Irwin K; Isenberg, Sherwin J; McArthur, David L; Del Signore, Madeline; McDonald, John S

    2011-03-01

    The purpose of this study was to measure, for the first time, multiple physiologic parameters of perfusion (pH, PCO2, PO2, and temperature) from the conjunctiva of adult patients during cardiopulmonary bypass while undergoing cardiothoracic surgery. Ten patients who underwent either intracardiac valve repair, atrial septal defect repair, or coronary artery bypass graft surgery had placement of a sensor which directly measured pH, PCO2, PO2, and temperature from the conjunctiva. Data were stratified into seven phases (0-5 minutes prior to bypass; 0-5, 6-10, and 11-15 minutes after initiation of bypass; 0-5 minutes prior to conclusion of bypass; and 0-5 and 6-10 minutes after bypass) and analyzed using a mixed model analysis.The change in conjunctival pH over the course of measurement was not statistically significant (p = .56). The PCO2 level followed a quadratic pattern, decreasing from a mean pre-bypass level of 37.7 mmHg at baseline prior to the initiation of cardiopulmonary bypass to a nadir of 33.2 mmHg, then increasing to a high of 39.4 mmHg at 6-10 minutes post bypass (p level of 79.5 mmHg to 31.3 mmHg by 6-10 minutes post bypass and even post-bypass, it never returned to baseline values (p levels as the patient was re-warmed following bypass (p < .01). There was no evidence of any eye injury or inflammation following the removal of the sensor. In the subjects studied, the conjunctival sensor yielded reproducible measurements during the various phases of cardiopulmonary bypass without ocular injury. Further study is necessary to determine the role of conjunctival measurements in critical settings.

  1. Alcohol-related massive eyelid swelling: case report Edema palpebral maciço relacionado ao uso de álcool: relato de caso

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    Vitorino Modesto dos Santos

    2007-02-01

    Full Text Available Alcohol-related massive eyelid edema has been rarely reported. The differential diagnosis includes local and systemic conditions. Alcohol itself can be associated with dermatological hypersensitivity reactions, appearing soon after alcoholic drinks. Massive bilateral eyelid swelling can constitute diagnostic pitfalls and therapeutic challenges to general practitioners with a placebo.Edema palpebral maciço relacionado ao uso de álcool tem sido raramente descrito. O diagnóstico diferencial inclui condições locais e sistêmicas. O próprio álcool pode estar associado com reações dermatológicas de hipersensibilidade, surgindo logo após uso de bebidas alcoólicas. Edema palpebral bilateral maciço pode constituir embaraços diagnósticos e desafios terapêuticos para os clínicos.

  2. Previously undescribed palpebral branch from the infraorbital canal: Application to surgery of the eyelid and treatment of orbital floor fractures.

    Science.gov (United States)

    Iwanaga, Joe; Watanabe, Koichi; Oskouian, Rod J; Tubbs, R Shane

    2017-09-01

    The sensory innervation of the inferior eyelid is mainly derived from the inferior palpebral branch (IPb) of the infraorbital nerve (ION). This study aimed to investigate another, to our knowledge, previously unknown branch, and elucidate its location and distribution. Twelve sides from seven fresh frozen cadaveric Caucasian heads were used in this study. The specimens were derived from two male and four female adult cadavers age. The diameter of the IPb of the ION (D1) and branch arising from the upper wall of the infraorbital canal (D2), and distance between the branching points of this branch and the anterior border of the orbit floor (L1) was measured. A branch to the lower eyelid was found arising from the infraorbital canal on the majority of sides. D1 ranged from 0.4 to 1.1 mm. The branch arising from the upper wall of the infraorbital canal was found 10 sides (83%). D2 ranged 0.6 to 1.0 mm. L1 ranged from 10.2 to 19.8 mm. All of the branches arising from the upper wall of the infraorbital canal (10 sides) primarily innervated to the inferior eyelid. We suggest this branch should be named the "posterior IPb" of the ION. Knowledge of this branch might decrease sensory loss following invasive procedures of the lower orbit. Clin. Anat. 30:835-838, 2017. © 2017Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  3. Análise do filme lacrimal e sua relação com a largura da fenda palpebral e a exoftalmia na oftalmopatia de Graves Tear film analysis and its relation with palpebral fissure height and exophthalmos in Graves' ophthalmopathy

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    Maria Vitoria Oliveira Moura Brasil

    2005-10-01

    Full Text Available OBJETIVO: Avaliar qualidade do filme lacrimal pelo corante rosa bengala e sua estabilidade por meio do tempo de ruptura, relacionando com a largura da fenda palpebral e a exoftalmia em pacientes com oftalmopatia de Graves. MÉTODOS: Foram estudados 54 olhos de 27 pacientes com oftalmopatia de Graves, tanto em fase inflamatória quanto em fase crônica. A avaliação consistiu de análise qualitativa do filme lacrimal pelo corante rosa bengala por meio da classificação de van Bijsterveld, análise da estabilidade do filme lacrimal pelo tempo de ruptura, medida da largura da fenda palpebral e exoftalmometria. A análise estatística foi realizada com o teste do Qui-quadrado. RESULTADOS: Entre os 27 pacientes estudados, 77,8% eram do sexo feminino e 22,2% do masculino. A idade média foi de 44,26 anos (DP 12,67. O tempo médio de doença foi de 5,85 anos (DP 4,47 e o de oftalmopatia foi de 5,81 anos (DP 5,37. Dos 54 olhos em estudo, 37% apresentaram teste positivo pela escala de graduação de van Bijsterveld, 33,3% tempo de ruptura do filme lacrimal menor que 5 segundos, 57,4% largura da fenda palpebral maior que 11 mm e 55,6% exoftalmometria maior que 19 mm. Quando relacionamos o tempo de ruptura do filme lacrimal menor que 5 segundos com a largura da fenda palpebral maior que 11 mm encontramos odds ratio igual a 11,2 (p=0,0008. As demais relações estudadas não mostraram significância estatística. CONCLUSÕES: O olho seco diagnosticado pela coloração com rosa bengala e pelo tempo de ruptura do filme lacrimal ocorre com freqüência na oftalmopatia de Graves. A largura da fenda palpebral correlaciona-se com o tempo de ruptura do filme lacrimal na oftalmopatia de Graves. Seu aumento pode levar à instabilidade do filme lacrimal.PURPOSE: To evaluate tear film quality by rose bengal staining and its stability by breakup time, relating with palpebral fissure height and exophthalmos in patients with Graves' ophthalmopathy. METHODS: We studied

  4. Avaliação da fenda palpebral após aplicação de toxina botulínica tipo A em pacientes com distonias faciais

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    Mariana Eleonora Pereira Cunial

    2012-12-01

    Full Text Available OBJETIVO: Avaliar a medida da fenda palpebral em pacientes com blefaroespasmo essencial benigno (BEB e espasmo hemifacial (EHF após a aplicação periocular de toxina botulínica tipo A. MÉTODOS: Foram estudados pacientes portadores de BEB e EHF submetidos à injeção periocular de toxina botulínica tipo A pela técnica inner orbital de aplicação. Os pacientes foram fotografados em PPO antes da aplicação e catorze dias depois dela. A fenda palpebral foi mensurada nestas imagens por meio de processamento computadorizado de imagens, utilizando o programa ImageJ. As alterações da fenda palpebral foram observadas comparando-se as medidas obtidas no pré e pós-aplicação. RESULTADOS: Comparando-se as imagens obtidas com o programa ImageJ, houve aumento estatisticamente significante (p<0,001 da fenda palpebral em 14 olhos (51,8% após a aplicação de injeção periocular da toxina botulínica e nenhuma das imagens analisadas apresentou diminuição da fenda palpebral. CONCLUSÃO: No presente estudo, os pacientes portadores de distonias faciais apresentaram aumento de fenda palpebral estatisticamente significante após aplicação periocular de toxina botulínica tipo A.

  5. Pre-banking microbial contamination of donor conjunctiva and storage medium for penetrating keratoplasty.

    Science.gov (United States)

    Inomata, Takenori; Ono, Koichi; Matsuba, Tsuyoshi; Shiang, Tina; Di Zazzo, Antonio; Nakatani, Satoru; Yamaguchi, Masahiro; Ebihara, Nobuyuki; Murakami, Akira

    2017-06-08

    The aims of this study were to investigate the incidence of positive donor tissue cultures before transfer to preservation medium (Optisol™-GS) for penetrating keratoplasty, to verify the efficacy of antibiotics contained in Optisol™-GS by examining the drug susceptibility and to assess the relationship between the results of our microbial assessments as well as donor factors and the incidence of contamination. We conducted a retrospective, cross-sectional study using Juntendo Eye Bank records for all corneal transplantations. Two hundred donor conjunctiva harvestings and storage medium (EP-II(®)) cultures were performed between July 2008 and June 2011. We analyzed the associations between donor factors (age, gender, history of cataract surgery, death-to-preservation interval, cause of death) and contamination rates using multivariate analysis by the generalized estimating equation model. We obtained positive bacterial cultures from 154 of the 200 eyes (77.0%). The isolated bacteria were indigenous, such as coagulase-negative Staphylococci, Corynebacterium sp., and methicillin-resistant Staphylococcus aureus (MRSA). There was significant resistance to levofloxacin (18 eyes, 9.0%) and gentamicin (12 eyes, 6.0%), and no vancomycin-resistant bacteria were detected. The donor factors did not correlate with the prevalence of bacterial contamination in our criteria. Pre-banking microbial assessment allows for microbial detection, bacterial susceptibility and resistance testing. This is useful for developing preservation mediums containing effective spectrum antibiotic agents for high quality control of corneal banking.

  6. Importance of Lid Hygiene Before Ocular Surgery: Qualitative and Quantitative Analysis of Eyelid and Conjunctiva Microbiota.

    Science.gov (United States)

    Peral, Assumpta; Alonso, Jose; García-García, Concepción; Niño-Rueda, Cristina; Calvo Del Bosque, Patricia

    2016-11-01

    To evaluate the efficacy of a cleansing eyelid wipe in reducing the microbiota present on the ocular surface before cataract surgery. A single-center, prospective, single-blind phase IV study was conducted at the University Complutense of Madrid. Forty-five adult patients who were scheduled for ocular surgery after treatment with commercially available eyelid wipes were consecutively enrolled. The study lasted 5 days and the patients were examined at day 0 (D0), day 3 (D3), and day 5 (D5). They received instructions to apply the eyelid wipe only to the eye subject to surgery, using the other eye as a control with no treatment. Lid and conjunctival swabs were taken on each day and microbes identified. Ocular surface microbiota was estimated by measuring the area of the agar plate occupied by the grown colonies with respect to the total available area. Measurements at D3 and D5 showed a percent reduction of 58% and 63%, respectively, in the microbial load on the eyelid in the treated eyes (P=0.0011). There was also a reduction, although nonsignificant, in the microbiota of the conjunctiva of 72% and 69% on D3 and D5, respectively. The degree of microbiota reduction was comparable with that obtained after topical application of antibiotics in other studies. The results suggest the use of these eyelid wipes as a complementary prophylactic method before any ocular surgery.

  7. Retina tissue engineering by conjunctiva mesenchymal stem cells encapsulated in fibrin gel: Hypotheses on novel approach to retinal diseases treatment.

    Science.gov (United States)

    Soleimannejad, Mostafa; Ebrahimi-Barough, Somayeh; Nadri, Samad; Riazi-Esfahani, Mohammad; Soleimani, Masoud; Tavangar, Seyed Mohammad; Ai, Jafar

    2017-04-01

    Retinitis pigmentosa (RP) and age related macular degeneration (AMD) are two retinal diseases that progress by photoreceptor cells death. In retinal transplantation studies, stem and progenitor cells inject into the sub retinal space or vitreous and then these cells can be migrate to the site of retinal degeneration and locate in the host retina and restitute vision. Our hypothesis suggests that using human conjunctiva stem cells (as the source for increasing the number of human stem cells progenitor cells in retina dysfunction diseases) with fibrin gel and also assessing its relating in vitro (cellular and molecular processes) and in vivo (vision tests and pathology) could be a promising strategy for treatment of AMD and RP disorders. In this idea, we describe a novel approach for retina tissue engineering with differentiation of conjunctiva mesenchymal stem cells (CJMSCs) into photoreceptor-like cells in fibrin gel with induction medium contain taurine. For assessment of differentiation, immunocytochemistry and real time PCR are used for the expression of Rhodopsin, RPE65, Nestin as differentiated photoreceptor cell markers in 2D and 3D culture. The results show that fibrin gel will offer a proper 3D scaffold for CJMSCs derived photoreceptor cell-like cells. Application of immune-privileged, readily available sources of adult stem cells like human conjunctiva stem cells with fibrin gel would be a promising strategy to increase the number of photoreceptor progenitor cells and promote involuntary angiogenesis needed in retina layer repair and regeneration. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Doença hepática aguda e edema palpebral persistente associados à mononucleose infecciosa

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    Mônica Ayres de A. Scattolin

    2007-05-01

    Full Text Available Este trabalho tem como objetivo relatar e discutir o caso clínico de um paciente portador de mononucleose infecciosa, tendo como manifestação inicial edema palpebral seguido de hepatopatia aguda e icterícia. Descrição - J.F.G.F., masculino, cinco anos, com histórico de sete dias de edema bipalpebral, conjuntivas hiperemiadas, cansaço, anorexia, febre moderada, vômitos e dor abdominal em hipocôndrio direito. Há um dia passou a apresentar icterícia, urina escura, exantema urticariforme, febre de 39,5ºC e diarréia, tendo sido internado para rehidratação e investigação diagnóstica. Ao exame físico de entrada, apresentava-se abatido, estado geral comprometido, FC: 96, FR: 30, febril, PA: 110x 60 mmHg, descorado +/4+, desidratado de 2º grau, eupnéico e ictérico ++, infartamento ganglionar assimétrico generalizado, mais acentuado em região cervical posterior. Sem alterações ao exame cardíaco e pulmonar. Abdômen distendido, doloroso à palpação, fígado a 4 cm e baço a 2,5 cm. A avaliação laboratorial revelou Hb: 10,1 g/dL, leucocitose moderada com acentuada linfocitose e atipia linfocitária evidente, ALT: 179 U/L, AST: 232 U/L, LDH: 2.103 U/L e bilirrubinas: total 6,7 mg/Dl (direta 4,9 mg/dL, urina tipo I com bilirrubinas ++ e ultra-som de abdômen com hepatoesplenomegalia inespecífica. As sorologias para toxoplasmose citomegalovírus, hepatite foram negativas e para o vírus Epstein-Barr (EBV reagente: IgG: 108 UA/mL, e IgM 28 UA/mL. Após hidratação parenteral e antitérmico, o paciente evoluiu com a melhora dos parâmetros clínicos e laboratoriais. Discussão - Estima-se, atualmente, que 50% das crianças menores de cinco anos já apresentaram infecção pelo EBV. Vários agentes causam lesão hepática aguda. Entre os vírus ressalta-se os das hepatites, entretanto, pode ocorrer hepatopatia aguda por outras causas virais, entre elas, mononucleose e citomegalia. Sabe-se que a hepatomegalia ocorre em 10% a 20

  9. Tratamento do lagoftalmo paralítico com a utilização do implante de peso de ouro recoberto pela aponeurose do músculo levantador palpebral Paralytic lagophthalmos treatment with gold weight implants covered by levator palpebrae muscle aponeurosis

    Directory of Open Access Journals (Sweden)

    Sergio Lessa

    2009-02-01

    Full Text Available OBJETIVO: Demonstrar a redução das complicações e melhora do resultado estético da correção do lagoftalmo paralítico com utilização de implantes de peso ouro através do recobrimento pela aponeurose do músculo levantador palpebral. MÉTODOS:Foram estudados vinte e nove pacientes portadores de paralisia facial idiopática com evolução clínica superior a 4 anos submetidos à correção cirúrgica do lagoftalmo paralítico com a utilização de uma modificação da técnica do implante de peso de ouro recoberto pela aponeurose do músculo levantador palpebral (Gladstone,1996 entre junho de 1997 e dezembro de 2006. Nenhum deles havia se submetido previamente a tratamentos cirúrgicos. RESULTADOS:Todos os pacientes apresentaram adaptação favorável dos implantes. Não houve casos de extrusão, deslocamento ou infecção, com melhora significativa da sintomatologia clínica e redução do lagoftalmo paralítico no período de acompanhamento pós-operatório que variou de 8 meses a 4 anos. CONCLUSÃO:Através da ampla dissecção da aponeurose do músculo levantador palpebral para recobrimento completo do implante do peso de ouro nós obtivemos excelentes resultados. O contorno da superfície cutânea pré-tarsal apresentou-se homogêneo, evitou-se a extrusão do implante e, comparativamente aos resultados apresentados pela técnica inicialmente descrita por Gladstone na qual realizava-se apenas a plicatura da aponeurose do músculo levantador palpebral sobre o implante de ouro, obtivemos um melhor controle do posicionamento final da pálpebra superior após o recobrimento do implante.POURPOSE: To demonstrate an improvement in paralytic lagophthalmos surgical treatment complications and aesthetic results by covering the gold weight implants with the levator palpebrae muscle aponeurosis. METHODS:We studied a case series of twenty nine patients presenting idiopatic facial palsy with more than 4 years of clinical evolution, submitted to

  10. Dynamics of an infectious keratoconjunctivitis outbreak by Mycoplasma conjunctivae on Pyrenean Chamois Rupicapra p. pyrenaica.

    Science.gov (United States)

    Arnal, Maríacruz; Herrero, Juan; de la Fe, Christian; Revilla, Miguel; Prada, Carlos; Martínez-Durán, David; Gómez-Martín, Angel; Fernández-Arberas, Olatz; Amores, Joaquín; Contreras, Antonio; García-Serrano, Alicia; de Luco, Daniel Fernández

    2013-01-01

    Between 2006 and 2008, an outbreak of Infectious Keratoconjunctivitis (IKC) affected Pyrenean chamois Rupicapra p. pyrenaica, an endemic subspecies of mountain ungulate that lives in the Pyrenees. The study focused on 14 mountain massifs (180,000 ha) where the species' population is stable. Cases of IKC were detected in ten of the massifs and, in five of them, mortality was substantial. The outbreak spread quickly from the first location detected, with two peaks in mortality that affected one (2007) and three (2008) massifs. In the latter, the peak was seasonal (spring to autumn) and, in the former, the outbreak persisted through winter. To identify the outbreak's aetiology, we examined 105 Pyrenean chamois clinically affected with IKC. TaqMan rt-PCR identified Mycoplasma conjunctivae in 93 (88.5%) of the chamois. Another rt-PCR detected Chlamydophila spp. in 14 of chamois, and 12 of those had mixed infections with mycoplasmas. In the period 2000-2007, the chamois population increased slightly (λ 1.026) but decreased significantly during the IKC outbreak (λ 0.8, 2007-2008; λ 0.85, 2008-2009) before increasing significantly after the outbreak (λ 1.1, 2009-2010). Sex-biased mortality shifted the adult sex ratio toward males (from 0.6 to 0.7 males per female) and reduced productivity slightly. Hunting was practically banned in the massifs where chamois experienced significant mortality and allowed again after the outbreak ended. Long-term monitoring of wild populations provides a basis for understanding the impacts of disease outbreaks and improves management decisions, particularly when species are subject to extractive exploitation.

  11. Microflora of conjunctiva in children and its sensitivity and resistance to antibacterial drugs

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    T. N. Vorontsova

    2012-01-01

    Full Text Available Purpose: Investigation of microflora of conjunctiva and its resistance to antibacterial drugs in healthy children and patients with various inflammatory eye diseases.Methods: We examined 402 children (421 eyes in the age from 1 month till 17 years: 62 healthy children (70 eyes and 340 pa- tients with different inflammatory diseases of anterior segment of eye (351 eyes. the smear was done in all children for plating and definition of sensitivity of microflora to antibacterial drugs by method of diffusion to agar.Results: the plating was positive even in 72.9% of healthy children who entered the hospital for the planned surgery. Most often we revealed Staphylococcus epidermidis (44.3%, Staphylococcus aureus (12.8%, Streptococcus faecalis (5.7% and Enterobacter (2.9%. In children with inflammatory diseases Staphylococcus epidermidis and Staphylococcus aureus (62.6% were found fre- quently. the analysis of data showed high level of resistance of all microflora to aminoglycosides (neomycin 37.8% and tobramycin 32.7% and chloramphenicol — 37.1%. the lowest resistance of all microflora was registered to levofloxacin (11.1% and ciprofloxacin (10.5%. In gram-negative microflora we revealed the maximal sensitivity to ciprofloxacin, in gram-positive — to levofloxacin.We detected the maximal resistance of microflora to ampicillin (66.1%, and minimal — to cephalosporines (4.5% among the antibiotics of systemic application.Conclusion: the findings allow us to recommend drops containing levofloxacin (Signicef for clinical practice in pediatric ophthalmology. 

  12. Granuloma conjuntival causado por fibras sintéticas Synthetic fiber granuloma of the conjunctiva

    Directory of Open Access Journals (Sweden)

    Patrícia Maria Fernandes Marback

    1999-10-01

    Full Text Available Objetivo: Relatar caso de granuloma de conjuntiva por fibras sintéticas. Relato do Caso: Paciente de seis anos, sexo feminino com história de tumoração em conjuntiva tarsal inferior do olho direito há seis meses. Foi realizada exérese da lesão. O laudo anátomo-patológico mostrou reação inflamatória granulomatosa do tipo corpo estranho com células gigantes multinucleadas fagocitando material birrefringente, compatível com fibras sintéticas. Discussão: O granuloma de fibras sintéticas de conjuntiva é raro e descrito principalmente em crianças, com acometimento unilateral, em conjuntiva tarsal inferior ou fundo de saco inferior. O freqüente contato com material de pelúcia nesta faixa etária tem sido apontado como fator etiológico. Granuloma de fibras sintéticas de conjuntiva deve ser considerado no diagnóstico diferencial de lesões tumorais de conjuntiva em crianças.Purpose: To report a case of conjunctival synthetic fiber granuloma. Case Report: Six-year old female presented with an inferior conjunctival tumor in the right eye for six months. The lesion was excised and histopathological examination revealed granulomatous inflammation and multinucleated giant cells phagocy birefringent material, recognized as synthetic fibers. Discussion: Synthetic fiber granuloma of the conjunctiva is an uncommon lesion described mainly in children. Usually it occurs unilaterally and situated in the inferior conjunc-tival fornix. The contact of the eye with toys containing synthetic fibers in this age group could explain the origin of the lesion. Synthetic fiber conjunctival granuloma should be included in the differential diagnosis of conjunctival tumors in children.

  13. Palpebral slant - eye

    Science.gov (United States)

    ... exam. Tests to confirm a disorder may include: Chromosome studies Enzyme assays Metabolic studies X-rays ... Dollfus H, Verloes A. Developmental anomalies of the lids. In: ... the Newborn . 9th ed. Philadelphia, PA: Elsevier Saunders; 2012: ...

  14. Incidence of epithelial lesions of the conjunctiva in a review of 12,102 specimens in Canada (Quebec

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    Luiz Filipe de Albuquerque Alves

    2011-02-01

    Full Text Available PURPOSE: The purpose of this study was to assess the relative frequency of epithelial lesions of the conjunctiva in Canada. METHODS: A retrospective study of 12,102 consecutive cases received during 16 years (1993-2009 at the Henry C. Witelson Ocular Pathology Laboratory in Montreal, Canada, was performed. Demographic data was retrieved from histopathological request forms and specimens were categorized and analyzed by mean percentage. The relative frequency of epithelial lesions of the conjunctiva from a single center in Canada, representing the province of Quebec was reviewed. RESULTS: Of the 12,102 specimens reviewed, 273 were conjunctival lesions (2.25%, including 86 epithelial tumors (0.71% of the conjunctiva that comprised the studied sample. The average age of these patients was 59.9 ± 17.6 years, and gender distribution was 66 (69% males and 30 (31% females. Fifteen lesions (17.4% were classified as squamous cell papillomas (mean age, 57.3 ± 16.7 years. Within the ocular surface squamous neoplasia (OSSN spectrum, there were 10 (11.6% actinic keratosis (63.8 ± 17.6 years, 27 (31.3% cases of conjunctival intraepithelial neoplasia (CIN with variable degrees of atypia (mild to moderate (63.9 ± 15.3 years, 15 (17.4% carcinomas in situ (66.7 ± 18.0 years, and 17 (19.7% squamous cell carcinomas (SCC (56.2 ± 19.4 years. Two other rare cases of malignant tumors included one basal cell carcinoma and one mucoepidermoid carcinoma. CONCLUSIONS: The distribution of our sample is similar to the one reported by the American Forces Institute of Pathology (AFIP in 1994. When we compare our sample to others coming from countries with high levels of sunlight exposure, we found a lower incidence of ocular surface squamous neoplasia, including squamous cell carcinomas in Canada.

  15. Rebamipide increases the amount of mucin-like substances on the conjunctiva and cornea in the N-acetylcysteine-treated in vivo model.

    Science.gov (United States)

    Urashima, Hiroki; Okamoto, Takashi; Takeji, Yasuhiro; Shinohara, Hisashi; Fujisawa, Shigeki

    2004-08-01

    Rebamipide increases the amount of mucin-like substances in the stomach. We aimed to determine the effects of rebamipide on the amount of mucin-like substances in the conjunctiva and cornea of N-acetylcysteine-treated eyes. Furthermore, we attempted to evaluate the effects of rebamipide on the wound healing of N-acetylcysteine-treated eyes. The model was created by instilling 10% N-acetylcysteine solutions into rabbit eyes. Rebamipide was then applied on the day following the completion of N-acetylcysteine treatment. The amount of mucin-like substances on the conjunctiva and cornea was measured using the Alcian-blue binding method. The degree of damage was evaluated using scores based on the areas and densities of the cornea and conjunctival after staining using a rose Bengal solution under blind conditions. Rebamipide increased the level of mucin-like substances on the conjunctiva of N-acetylcysteine-treated eyes when instilled at concentrations of 0.3% or higher, and 1% rebamipide increased the amount of mucin-like substances covering the cornea. Moreover, 1% rebamipide improved the rose Bengal scores of the cornea and conjunctiva in N-acetylcysteine-treated eyes. Rebamipide increased mucin-like substances on the cornea and conjunctiva of N-acetylcysteine-treated eyes. In accordance with the mucin-increasing effects, rebamipide improved the rose Bengal scores for the cornea and conjunctiva of N-acetylcysteine-treated eyes. However, the relevance of these findings to dry eyes is unclear because it is not known whether the change in mucus expression in the N-acetylcysteine model is similar to what occurs in aqueous tear deficiency. Consequently, it may be worth trying on an animal model of keratoconjunctivitis sicca.

  16. Nevus y Melanoma de la conjuntiva ocular: Reporte de 3 casos Nevus and melanoma of the ocular conjunctiva: Report of 3 cases

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    Yolanda I. Hechavarría Duque

    2003-06-01

    Full Text Available Se reportó el estudio de las historias clínicas de 3 pacientes portadores de nevus de la conjuntiva ocular que evolucionó de manera desfavorable hacia melanoma de la conjuntiva, por lo que se plantea que el mejor tratamiento es el profiláctico en estos casos. Se realizaron conclusiones y recomendaciones.The study of the medical histories of 3 patients carriers of nevus of the ocular conjunctiva that evolved unfavorably towards melanoma of the conjunctiva is dealt with. As a result, it is stated that the prophylactic treatment is the best in these cases. Conclusions are reached and recommendations are made.

  17. Superior Hiking Trail

    Data.gov (United States)

    Minnesota Department of Natural Resources — Superior Hiking Trail main trail, spurs, and camp spurs for completed trail throughout Cook, Lake, St. Louis and Carlton counties. These data were collected with...

  18. Bathymetry of Lake Superior

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Bathymetry of Lake Superior has been compiled as a component of a NOAA project to rescue Great Lakes lake floor geological and geophysical data and make it more...

  19. Superior Hiking Trail Facilities

    Data.gov (United States)

    Minnesota Department of Natural Resources — Superior Hiking Trail main trail, spurs, and camp spurs for completed trail throughout Cook, Lake, St. Louis and Carlton counties. These data were collected with...

  20. The ocular conjunctiva as a mucosal immunization route: a profile of the immune response to the model antigen tetanus toxoid.

    Science.gov (United States)

    Barisani-Asenbauer, Talin; Inic-Kanada, Aleksandra; Belij, Sandra; Marinkovic, Emilija; Stojicevic, Ivana; Montanaro, Jacqueline; Stein, Elisabeth; Bintner, Nora; Stojanovic, Marijana

    2013-01-01

    In a quest for a needle-free vaccine administration strategy, we evaluated the ocular conjunctiva as an alternative mucosal immunization route by profiling and comparing the local and systemic immune responses to the subcutaneous or conjunctival administration of tetanus toxoid (TTd), a model antigen. BALB/c and C57BL/6 mice were immunized either subcutaneously with TTd alone or via the conjunctiva with TTd alone, TTd mixed with 2% glycerol or TTd with merthiolate-inactivated whole-cell B. pertussis (wBP) as adjuvants. Mice were immunized on days 0, 7 and 14 via both routes, and an evaluation of the local and systemic immune responses was performed two weeks after the last immunization. Four weeks after the last immunization, the mice were challenged with a lethal dose (2 × LD50) of tetanus toxin. The conjunctival application of TTd in BALB/c mice induced TTd-specific secretory IgA production and skewed the TTd-specific immune response toward a Th1/Th17 profile, as determined by the stimulation of IFNγ and IL-17A secretion and/or the concurrent pronounced reduction of IL-4 secretion, irrespective of the adjuvant. In conjunctivaly immunized C57BL/6 mice, only TTd administered with wBP promoted the establishment of a mixed Th1/Th17 TTd-specific immune response, whereas TTd alone or TTd in conjunction with glycerol initiated a dominant Th1 response against TTd. Immunization via the conjunctiva with TTd plus wBP adjuvant resulted in a 33% survival rate of challenged mice compared to a 0% survival rate in non-immunized animals (p<0.05). Conjunctival immunization with TTd alone or with various adjuvants induced TTd-specific local and systemic immune responses, predominantly of the Th1 type. The strongest immune responses developed in mice that received TTd together with wBP, which implies that this alternative route might tailor the immune response to fight intracellular bacteria or viruses more effectively.

  1. Normal flora of conjunctiva and lid margin, as well as its antibiotic sensitivity, in patients undergoing cataract surgery at Phramongkutklao Hospital

    Science.gov (United States)

    Ratnumnoi, Ravee; Keorochana, Narumon; Sontisombat, Chavalit

    2017-01-01

    Objective This study aimed to evaluate the normal flora of conjunctiva and lid margin, as well as its antibiotic sensitivity. Design This was a prospective cross-sectional study. Patients and methods A prospective study was conducted on 120 patients who underwent cataract surgery at the Phramongkutklao Hospital from September 2014 to October 2014. Conjunctival and lid margin swabs were obtained from patients before they underwent cataract surgery. These swabs were used to inoculate blood agar and chocolate agar plates for culturing. After growth of the normal flora, the antibiotic sensitivity method using tobramycin, moxifloxacin, levofloxacin, and cefazolin was applied. Main outcome measures Normal flora of conjunctiva and lid margin, along with its antibiotic sensitivity, from patients who underwent cataract surgery was assessed. Results A total of 120 eyes were included in this study, and bacterial isolation rates were identified. Five bacteria from the lid margin were cultured, namely, coagulase-negative staphylococcus (58.33%), Streptococcus spp. (2.5%), Corynebacterium (1.67%), Micrococcus spp. (1.67%), and Staphylococcus aureus (0.83%). Two bacteria from the conjunctiva were cultured, namely, coagulase-negative staphylococcus (30%) and Streptococcus spp. (0.83%). Results of antibiotic sensitivity test showed that all isolated bacteria are sensitive to cefazolin 100%, tobramycin 98.67%, levofloxacin 100%, and moxifloxacin 100%. Conclusion Coagulase-negative staphylococci are the most common bacteria isolated from conjunctiva and lid margin. PMID:28203050

  2. Direct detection of Ehrlichia canis by PCR in the conjunctiva of a dog with bilateral anterior uveitis.

    Science.gov (United States)

    Walser-Reinhard, L; Schaarschmidt-Kiener, D; Forster, J L; Matheis, F; Spiess, B

    2012-04-01

    The following report describes the direct detection of Ehrlichia canis by real-time PCR in the conjunctiva of a 1-year-old female Maltese dog. After being imported from Brazil, the dog was presented because of anorexia, dehydration, fever, and palpable mandibular lymph nodes. A few days later, the dog developed bilateral blepharospasm, photophobia and anterior uveitis. Monocytic ehrlichia was diagnosed by a positive PCR result and the detection of IgM and IgG antibodies. Because of the massive uveitis a conjunctival sample was taken with a cytobrush, which also tested positive for Ehrlichia canis DNA by real-time PCR. Only one week after starting treatment with systemic doxycycline and local anti-inflammatory and cyclopalgic therapy the dog recovered from systemic and eye diseases. After therapy the follow-up examination revealed a full remission of clinical and hematological parameters and negative PCR result.

  3. Identification of bap and icaA genes involved in biofilm formation in coagulase negative staphylococci isolated from feline conjunctiva.

    Science.gov (United States)

    Płoneczka-Janeczko, Katarzyna; Lis, Paweł; Bierowiec, Karolina; Rypuła, Krzysztof; Chorbiński, Paweł

    2014-12-01

    Bap and icaA genes are commonly known to be involved in the biofilm formation. The prevalence of bap and icaA genes and biofilm formation was determined in conjunctival isolates of coagulase negative staphylococci (CNS) collected from cats. The study was conducted on 90 archival CNS isolates collected from feline conjunctiva obtained from clinically healthy cats and cats with ocular problems. Biofilm formation was examined using the microtiter plate (MTP) method. The prevalence of icaA and bap genes was determined using polymerase chain reaction (PCR). Genetic profiles of the bap-positive isolates were examined using the modified random amplified polymorphic DNA (RAPD) method. Of the 90 CNS isolates investigated, 58.9% (53/90) were confirmed to form biofilms on a polystyrene plate after 24 h, and the intensity of the biofilm production varied strongly between positive strains. Among the biofilm-producing isolates, 24.5% (13/53) carried the icaA gene and 3.8% (2/53) carried the bap gene. Among the isolates that did not produce biofilms, the icaA gene and bap gene were detected in 8.1% (3/37) and 2.7% (1/37) of isolates, respectively. This is the first report demonstrating that CNS isolated from feline conjunctiva can potentially be a bap gene reservoir. Preliminary comparison of the genetic profiles of three bap-positive isolates collected from cats showed that each of the isolates has a different genetic background with a high similarity with the human strain of S. epidermidis.

  4. Prevalence, molecular diagnosis and treatment of Mycoplasma conjunctivae isolated from infectious keratoconjunctivitis affected Lohi sheep maintained at Livestock Experiment Station, Bahadurnagar, Okara, Pakistan.

    Science.gov (United States)

    Shahzad, Waseem; Munir, Rashid; Rana, Mohammad Younus; Ahmad, Rashid; Khan, Mohammad Sarwar; Akbar, Ghulam; Ijaz, Mohammad; Mehmood, Fayyaz

    2013-03-01

    Mycoplasma conjunctivae are etiological agents of infectious keratoconjunctivitis (IKC), commonly known as pink-eye in domestic sheep, goats and other wild animals in many parts of the world. A few young Lohi lambs maintained at Livestock Experiment Station (LES), Bahadurnagar, Okara, Pakistan showed clinical signs and symptoms of conjunctivitis, keratitis, severe lacrimation and varying degree of blindness. During January to March, 2011, a total of 36 ocular swabs were collected from IKC affected animals and were processed for isolation, identification, and characterization of M. conjunctivae. Sixteen (44.44 %) out of 36 samples showed turbidity in PPLO broth. Twelve (75 %) out of 16 broth samples showed colony growth on PPLO agar. All 16 (44.44 %) out of 36 turbid broth samples, 12 (75 %) out of 16 cultured on agar plate samples, and 21 (59 %) out of 36 sheep ocular direct swab samples were found positive for M. conjunctivae through polymerase chain reaction test by using M. conjunctivae-specific primer pair McoF1 and McoR1 and detecting a 750 base pair fragment on agarose gel. Topical application of 0.5 % sterile solution of gentamycin (100 mg/ml) (Gentafar 10 %, FARVET, Netherlands) proved suitable for the treatment of IKC in Lohi lambs as all clinical signs of IKC disappeared after 5 days of treatment with this antibiotic. This is the first report about the prevalence, molecular diagnosis, and treatment of M. conjunctivae in Lohi sheep affected with infectious keratoconjunctivitis at LES, Bahadurnagar, Okara, Pakistan.

  5. PERSISTENT LEFT SUPERIOR VENACAVA

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    Devinder Singh

    2014-05-01

    Full Text Available A Persistent Left Superior Venacava (PLSVC is the most common variation of the thoracic venous system and rare congenital vascular anomaly and is prevalent in 0.3% of the population. It may be associated with other cardiovascular abnormalities including atrial septal defect, bicuspid aortic valve, coarctation of aorta, coronary sinus ostial atresia, and cor triatriatum. Incidental rotation of a dilated coronary sinus on echocardiography should raise the suspicion of PLSVC. The diagnosis should be confirmed by saline contrast echocardiography. Condition is usually asymptomatic. Here we present a rare case of persistent left superior vena cava presented in OPD with dyspnoea & palpitations.

  6. Tratamiento del xantogranuloma palpebral en el adulto mediante colgajos en isla del área zigomática Treatment of adult eyebrow xanthogranuloma with a zygomatic island flap

    Directory of Open Access Journals (Sweden)

    C. León Llerena

    2009-06-01

    Full Text Available El término Xantoma, introducido por Frank Smith en 1869, significa tumor amarillo. El Xantogranuloma en el adulto es una afección cutánea inusual, de localización única, sin afectación visceral y que no remite espontáneamente. La afectación palpebral representa el 25% de los casos y en la mayoría de los casos suele ser un nódulo solitario. Presentamos el caso de un paciente varón de 58 años que acude a nuestro Servicio de Cirugía Plástica por presentar extensas lesiones palpebrales nodulares y bilaterales, de crecimiento lento y coloración amarillenta. Las lesiones fueron diagnosticadas histopatológicamente como xantogranulomas. El defecto palpebral fue reparado mediante un colgajo en isla del área zigomática, descrito por Heywood en 1991, modificado en su diseño original. Nuestro objetivo es describir el Xantogranuloma en el adulto por tratarse de una patología poco frecuente, sus características histológicas y sus posibles diagnósticos diferenciales. Destacamos la utilidad y versatilidad del colgajo zigomático ampliado como una excelente alternativa para la reparación de amplios defectos cutáneos palpebrales inferiores.The term anthoma, meaning yellow tumor, was introduced by Frank Smith in 1869. Xanthogranuloma in adults is an unusual single-site, cutaneous tumor, with no visceral involvement and without spontaneous regress. Palpebral xanthomas account for 25% of all cases, most of which usually involve a solitary nodule. We present a 58-year-old man who was referred to our Plastic Surgery Service with large, yellowish, slow-growing, bilateral palpebral lesions. The histological diagnosis was xanthogranuloma. The palpebral defect was repaired using an island flap from the zygomatic area, described by Heywood in 1991 and modified from the original design. We describe adult xanthogranulomas, which are unusual lesions, and discuss the histological study and differential diagnosis. We also draw atention to the usefulness

  7. Resultados postquirúrgicos de la ptosis palpebral asociada a Síndromes. ICO Ramón Pando Ferrer.2005- 2006.

    Directory of Open Access Journals (Sweden)

    María Elena Ríos Rodríguez

    2007-10-01

    Full Text Available Se realizó un estudio observacional, descriptivo, retrospectivo, en pacientes con síndromes asociados a ptosis palpebral en el ICO Ramón Pando Ferrer en el período comprendido entre enero 2005 y diciembre del 2006. Se estudiaron un total de 32 pacientes y 44 ojos. El 43.7% tenían entre 20 – 39 años. No hubo diferencias en la distribución por sexo, aunque con ligera inclinación hacia el sexo femenino. Más del 50% de las ptosis eran bilaterales. Según etiología predominaron las miogénicas para un 59.3%, y dentro de ellas las congénitas representadas por el síndrome de blefarofímosis (31.2%, y las adquiridas por la Miastenia Gravis (15.6%. Las ptosis neurogénicas constituyen un 34.3% representadas por la parálisis el III par y el síndrome de Marcus Gunn, para un 12.5% y 9.3% respectivamente. El 81.2% de los síndromes tuvieron posibilidades quirúrgicas. Al 66% del total de ojos se les realizó la suspensión al músculo frontal y al resto el reforzamiento de la aponeurosis y la Fasanella Servat Modificada en un 20.4% y 13.6% respectivamente. Los resultados se calificaron de buenos en el 54.5%, regulares en el 45.4% y ninguno tuvo malos resultados. Las complicaciones que se presentaron fueron mínimas representadas por la hipocorrección en el reforzamiento de la aponeurosis para un 44.4%. El 79.5% no presentaron complicaciones. Concluimos que muchos síndromes asociados a las ptosis palpebral pueden ser corregidos quirúrgicamente contribuyendo a mejorar la calidad de vida de estos pacientes.

  8. Air Superiority Fighter Characteristics.

    Science.gov (United States)

    1998-06-05

    many a dispute could have been deflated into a single paragraph if the disputants had just dared to define their terms.7 Aristotle ...meaningful. This section will expand on some key ideology concepts. The phrase "air superiority fighter" may bring to mind visions of fighter... biographies are useful in garnering airpower advocate theories as well as identifying key characteristics. Air campaign results, starting with World

  9. Evaluation for High-risk HPV in Squamous Cell Carcinomas and Precursor Lesions Arising in the Conjunctiva and Lacrimal Sac.

    Science.gov (United States)

    Afrogheh, Amir H; Jakobiec, Frederick A; Hammon, Rebecca; Grossniklaus, Hans E; Rocco, James; Lindeman, Neal I; Sadow, Peter M; Faquin, William C

    2016-04-01

    High-risk human papilloma virus (HR-HPV) is a well-established causative agent of oropharyngeal squamous cell carcinoma (SCC). In addition, HR-HPV has occasionally been reported to be present in dysplastic and malignant lesions of the conjunctiva and lacrimal sac, although its overall incidence and etiological role in periocular SCC are controversial. Sequential surgical samples of 52 combined cases of invasive SCC (I-SCC) and SCC in situ (SCCIS) from 2 periocular sites (conjunctiva and lacrimal sac) diagnosed over a 14-year period (2000 to 2014) were selected for evaluation, and relevant patient characteristics were documented. p16 immunohistochemistry was performed as a screening test. All p16-positive cases were further evaluated for HR-HPV using DNA in situ hybridization (DNA ISH), and a subset was also analyzed by polymerase chain reaction (PCR). Of 43 ocular surface squamous neoplasias (OSSNs), 30% (n=13; 8 SCCIS and 5 I-SCC cases) were positive for HR-HPV. HPV-positive OSSNs occurred in 8 men and 5 women with a mean age of 60 years (range, 39 to 94 y). HPV type-16 was detected in all conjunctival cases evaluated by PCR. All 5 conjunctival I-SCCs were nonkeratinizing (n=4) or partially keratinizing (n=1) and managed by simple excision. In contrast, HPV-negative conjunctival I-SCCs were predominantly keratinizing (11 keratinizing and 2 nonkeratinizing). Of 9 lacrimal sac I-SCCs (LSSCCs), 66.7% (n=6) were positive for HR-HPV by p16 and DNA ISH; HPV subtypes were HPV-16 (n=5) and HPV-58 (n=1). In addition, 2 p16-positive cases with negative DNA ISH results were HR-HPV positive (HPV-16 and HPV-33) when evaluated by PCR, suggesting that the rate of HR-HPV positivity among the LSSCCs may be as high as 89% (n=8). The combined group of HR-HPV-positive LSSCCs was seen in 4 men and 4 women with a mean age of 60 years (range, 34 to 71 y). Seven of the 8 HPV-positive LSSCCs (87.5%) had a nonkeratinizing or partially keratinizing histomorphology, whereas 1 case (12

  10. Carcinoma sebáceo palpebral: Presentación de un caso Palpeebral sebaceous carcinoma: A case report

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    María Cáceres Toledo

    1999-06-01

    Full Text Available Se presenta a un paciente de 26 años de edad, con diagnóstico clínico de chalación gigante del párpado inferior del ojo derecho de 6 meses de evolución, con un gran componente inflamatorio y bordes ulcerados que no había respondido a la terapéutica médica ni quirúrgica. El resultado de la biopsia tomada de este lesión fue, carcinoma epidermoide infiltrante, por lo que decidimos hacer la cirugía con margen oncológico, que requirió de un colgajo libre del párpado superior con fines estéticos y funcionales. El estudio histológico de la tumoración evidenció un carcinoma sebáceo. La evolución posoperatoria de este paciente, al año de operado, ha sido satisfactoriaA 26-year-old patient wich clinical diagnosis of giant chalazi on of the lower eyelid of the right eye with 6 months of evolution and with a great inflamatory component and ulcerated edges that had not responded to mechical and surgical therapeutics is presented. The result of the biopsy was infiltrating epidermoid carcinoma, so it was decided to perform surgery with oncological margin that required a free flap of the upper eyelid with aesthetic functional ends. The histological study of the tumor proved the existance of a sebaceous carcinoma. The posoperative evolution of the patient after a year has been satisfactory

  11. Normal flora of conjunctiva and lid margin, as well as its antibiotic sensitivity, in patients undergoing cataract surgery at Phramongkutklao Hospital

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    Ratnumnoi R

    2017-01-01

    Full Text Available Ravee Ratnumnoi, Narumon Keorochana, Chavalit Sontisombat Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand Objective: This study aimed to evaluate the normal flora of conjunctiva and lid margin, as well as its antibiotic sensitivity. Design: This was a prospective cross-sectional study. Patients and methods: A prospective study was conducted on 120 patients who underwent cataract surgery at the Phramongkutklao Hospital from September 2014 to October 2014. Conjunctival and lid margin swabs were obtained from patients before they underwent cataract surgery. These swabs were used to inoculate blood agar and chocolate agar plates for culturing. After growth of the normal flora, the antibiotic sensitivity method using tobramycin, moxifloxacin, levofloxacin, and cefazolin was applied. Main outcome measures: Normal flora of conjunctiva and lid margin, along with its antibiotic sensitivity, from patients who underwent cataract surgery was assessed. Results: A total of 120 eyes were included in this study, and bacterial isolation rates were identified. Five bacteria from the lid margin were cultured, namely, coagulase-negative staphylococcus (58.33%, Streptococcus spp. (2.5%, Corynebacterium (1.67%, Micrococcus spp. (1.67%, and Staphylococcus aureus (0.83%. Two bacteria from the conjunctiva were cultured, namely, coagulase-negative staphylococcus (30% and Streptococcus spp. (0.83%. Results of antibiotic sensitivity test showed that all isolated bacteria are sensitive to cefazolin 100%, tobramycin 98.67%, levofloxacin 100%, and moxifloxacin 100%. Conclusion: Coagulase-negative staphylococci are the most common bacteria isolated from conjunctiva and lid margin. Keywords: conjunctival flora, lid margin flora, cataract surgery, sensitivity, antibiotics

  12. Contabilidad Financiera Superior

    OpenAIRE

    Ipiñazar Petralanda, Izaskun

    2013-01-01

    Duración (en horas): De 31 a 40 horas. Destinatario: Estudiante y Docente A través de este material se presentan las pautas necesarias para implementar un aprendizaje basado en problemas en la asignatura de Contabilidad Financiera Superior dentro de los temas “Constitución de S.A. y S.R.L.” (Tema 2), “Ampliaciones de Capital” (Tema 3) y “Reducciones de Capital” (Tema 4). En primer lugar se presentan las guías generales de la asignatura, y a continuación, las diferentes activida...

  13. Contabilidad Financiera Superior

    OpenAIRE

    Ipiñazar Petralanda, Izaskun

    2013-01-01

    Duración (en horas): De 31 a 40 horas. Destinatario: Estudiante y Docente A través de este material se presentan las pautas necesarias para implementar un aprendizaje basado en problemas en la asignatura de Contabilidad Financiera Superior dentro de los temas “Constitución de S.A. y S.R.L.” (Tema 2), “Ampliaciones de Capital” (Tema 3) y “Reducciones de Capital” (Tema 4). En primer lugar se presentan las guías generales de la asignatura, y a continuación, las diferentes activida...

  14. Paracoccidioidomicose primária de pálpebra e conjuntiva Primary paracoccidioidomycosis of eyelid and conjunctiva

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    Ezon Ferraz

    2001-06-01

    Full Text Available A paracoccidioidomicose (Pbmicose é a micose profunda mais freqüente no Brasil, mas o acometimento ocular é raro e, quando presente, geralmente secundário. Os autores relatam caso de Pbmicose pálpebro-conjuntival em que não foi encontrado foco extra-ocular. É feita uma revisão da literatura e discutida a importância da suspeita diagnóstica em população de risco e do tratamento precoce desta condição para o bom prognóstico visual.Paracoccidioidomycosis is the most frequent systemic mycosis in Brazil, but ocular involvement is rare and, if present, often secondary to another site. The authors report a case of paracoccidioidomycosis of eyelid and conjunctiva where no extraocular focus was found. A brief review of the literature is made discussing the importance of diagnostic suspecion in a population at risk and early treatment for a good visual prognosis.

  15. SU-E-T-55: A Novel Applicator for High Dose Rate Brachytherapy Treatments of Ocular Conjunctiva

    Energy Technology Data Exchange (ETDEWEB)

    Koren, S; Bragilovski, D [Rabin Medical Center, Petah Tikva (Israel); Tafo, A Guemnie [Institut Gustave Roussy, Paris (France); Cohen, G [Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

    2015-06-15

    Purpose: To evaluate the clinical feasibility of IntraBeam intra operative kV irradiation beam device for ocular conjunctiva treatments. The Intra-Beam system offers a 4.4 mm diameter needle applicator, that is not suitable for treatment of a large surface with limits access. We propose an adaptor that will answer to this clinical need and provide initial dosimetry. Methods: The dose distribution of the needle applicator is non uniform and hence not suitable for treatment of relatively large surfaces. We designed an adapter to the needle applicator that will filter the X-rays and produce a conformal dose distribution over the treatment area while shielding surfaces to be spared. Dose distributions were simulated using FLUKA is a fully integrated particle physics Monte Carlo simulation package. Results: We designed a wedge applicator made of Polythermide window and stainless steel for collimating. We compare the dose distribution to that of the known needle and surface applicators. Conclusion: Initial dosimetry shows feasibility of this approach. While further refinements to the design may be warranted, the results support construction of a prototype and confirmation of the Monte Carlo dosimetry with measured data.

  16. Blockage of complement regulators in the conjunctiva and within the eye leads to massive inflammation and iritis.

    Science.gov (United States)

    Bardenstein, D S; Cheyer, C J; Lee, C; Cocuzzi, E; Mizuno, M; Okada, N; Medof, M E

    2001-12-01

    The open environment of the eye is continuously subject to an influx of foreign agents that can activate complement. Decay-accelerating factor (DAF), membrane cofactor protein (MCP) and CD59 are regulators that protect self-cells from autologous complement activation on their surfaces. They are expressed in the eye at unusually high levels but their physiological importance in this site is unstudied. In the rat, a structural analogue termed 5I2 antigen (5I2 Ag) has actions overlapping DAF and MCP. In this investigation, we injected F(ab')2 fragments of 5I2 mAb into the conjunctiva and aqueous humor, in the latter case with and without concomitant blockage of CD59. Massive neutrophilic infiltration of the stroma and iris resulted upon blocking 5I2 Ag activity. Frank necrosis of the iris occurred upon concomitant intraocular blockage of CD59. C3b was identified immunohistochemically, and minimal effects were seen in complement-depleted animals and in those treated with non-relevant antibody. The finding that blockage of 5I2 Ag function in periocular tissues and within the eye causes intense conjunctival inflammation and iritis demonstrates the importance of intrinsic complement regulators in protecting ocular tissues from spontaneous or bystander attack by autologous complement.

  17. Giemsa-based cytological assessment of area, shape and nucleus:cytoplasm ratio of goblet cells of rabbit bulbar conjunctiva.

    Science.gov (United States)

    Doughty, M J

    2016-11-01

    Goblet cells were visualized in impression cytology specimens from bulbar conjunctiva of the rabbit eye using Giemsa staining. Highly magnified images were used to generate outlines of the goblet cells and their characteristic eccentric nuclei. Using sets of 10 cells from 15 cytology specimens, I found that the longest dimension of the goblet cells averaged 16.7 ± 2.3 μm, the shortest dimension averaged 14.4 ± 1.8 μm and the nucleus averaged 6.3 ± 0.8 μm. The goblet cells were ellipsoid in shape and the longest:shortest cell dimension ratio averaged 1.169 ± 0.091. The goblet cell areas ranged from 108 to 338 μm(2) (average 193 ± 50 μm(2)). The area could be predicted reliably from the longest and shortest dimensions (r(2) = 0.903). The areas of goblet cell nuclei were 15-58 μm(2) (average 33 ± μm(2)) and the nucleus:cytoplasm area fraction was predictably greater in smaller goblet cells and less in the larger goblet cells (Spearman correlation = 0.817). The nuclei were estimated to occupy an average of 9.5% of the cell volume. The differences in size, shape and nucleus:cytoplasm ratio may reflect differences in goblet cell maturation.

  18. GP2-expressing cells in the conjunctiva and tear ducts of mice: identification of a novel type of cells in the squamous stratified epithelium.

    Science.gov (United States)

    Kimura, Shunsuke; Kishimoto, Ayuko; Mutoh, Mami; Takahashi-Iwanaga, Hiromi; Iwanaga, Toshihiko

    2015-01-01

    GP2 is a membrane-associated secretory protein originally identified in zymogen granules of pancreatic acinar cells. Recently, this glycoprotein has attracted attention as a marker substance of M cells of Peyer's patches and for its involvement in the selective uptake of pathological bacteria via M cells. When we stained the conjunctiva and tear ducts of mice using a GP2 antibody, all goblet cells in the squamous stratified epithelium of the conjunctiva were intensely immunolabeled, while goblet cells in the intestine and airway were devoid of the immunoreactivity, indicating that the conjunctiva contains a special type of goblet cell. Further immunostaining for GP-2 labeled dispersed cells of peculiar shapes within the stratified squamous epithelium in the lacrimal canaliculi, lacrimal sac, and nasolacrimal duct. The GP2-immunoreactive cells in the tear duct projected arched or branched processes toward the basement membrane. Electron-microscopically, immunogold particles for GP2 outlined the basolateral plasma membrane of both the conjuntival goblet cells and the peculiarly shaped cells in the tear duct. Intracellularly, GP2 products of the goblet cells were localized around secretory granules in the apical cytoplasm and those of the tear duct cells inside the vesicles. The luminal contents close to apical plasma membrane were heavily labeled with immunogold particles, suggesting an exocytosis-based targeting of GP2 to the plasma membrane and its release into the lumen. The possible function of GP2 in tear ducts is discussed in relation to a defense system against invasive microoranisms and antigens.

  19. Insight into behavior of epithelial cells of the feline conjunctiva in chronic conjunctivitis as a possible limitation in detection of Chlamydophila spp.

    Science.gov (United States)

    Kiełbowicz, Z; Płoneczka-Janeczko, K; Kuropka, P

    2014-01-01

    The aims of this work was documentation of the reactivity of feline conjunctival epithelial cells in chronic conjunctivitis and the investigation of a possible correlation of histological findings in conjunctiva with a limitation in detection of the pathogen. In this observational study, conjunctival swab samples collected from six cats suffering from chronic conjunctivitis were monitored for Chlamydophila spp. infection for one month, every ten days. Chlamydophilosis was diagnosed by conventional PCR, and confirmed by sequencing analysis. A lack of coherence with results in subsequent studies using PCR did not allow an accurate diagnosis. Additional bioptat samples of conjunctiva were collected for diagnostic purposes and stained in haematoxylin and eosin following the Giemsa method for light microscopic analysis. Additionally the samples were incubated for 15 min with IMAGEN Chlamydia conjugate (IMAGEN Chlamydia reagent kit, Dako, UK), allowing immunofluorescence detection of Chlamydophila spp. Within the epithelium an increased number of goblet cells, as well as general enlargement of the epithelium and a reduced number of normal epithelial cells, was observed. Only in areas of low epithelium could structures similar to the elementary bodies of Chlamydophila spp. be distinguished. The presented data document a possible limitation in molecular evidence for chlamydophila infection in some naturally infected cats, taking into account histological conditions in conjunctiva at the same time.

  20. Statistics of superior records

    Science.gov (United States)

    Ben-Naim, E.; Krapivsky, P. L.

    2013-08-01

    We study statistics of records in a sequence of random variables. These identical and independently distributed variables are drawn from the parent distribution ρ. The running record equals the maximum of all elements in the sequence up to a given point. We define a superior sequence as one where all running records are above the average record expected for the parent distribution ρ. We find that the fraction of superior sequences SN decays algebraically with sequence length N, SN˜N-β in the limit N→∞. Interestingly, the decay exponent β is nontrivial, being the root of an integral equation. For example, when ρ is a uniform distribution with compact support, we find β=0.450265. In general, the tail of the parent distribution governs the exponent β. We also consider the dual problem of inferior sequences, where all records are below average, and find that the fraction of inferior sequences IN decays algebraically, albeit with a different decay exponent, IN˜N-α. We use the above statistical measures to analyze earthquake data.

  1. Frenillo labial superior doble

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    Carlos Albornoz López del Castillo

    Full Text Available El frenillo labial superior doble no sindrómico es una anomalía del desarrollo que no hemos encontrado reportada en la revisión bibliográfica realizada. Se presenta una niña de 11 años de edad que fue remitida al servicio de Cirugía Maxilofacial del Hospital "Eduardo Agramonte Piña", de Camagüey, por presentar un frenillo labial superior doble de baja inserción. Se describen los síntomas clínicos asociados a esta anomalía y el tratamiento quirúrgico utilizado para su solución: una frenectomía y plastia sobre la banda muscular frénica anormal que provocaba exceso de tejido en la mucosa labial. Consideramos muy interesante la descripción de este caso, por no haber encontrado reporte similar en la literatura revisada.

  2. 5-Fluorouracil for the treatment of intraepithelial neoplasia and squamous cell carcinoma of the conjunctiva, and cornea

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    Abdulmoghni Al-Barrag

    2010-07-01

    Full Text Available Abdulmoghni Al-Barrag1, Mutahar Al-Shaer1, Nabil Al-Matary2, Mohammed Al-Hamdani21Ophthalmic Department, Faculty of Medicine and Health Sciences, Sana’a University, Sana’a, Republic of Yemen; 2Ophthalmic Department, Military Hospital, Sana’a, Republic of YemenObjective: To evaluate the efficacy and risks of complications of pulse dosing of topical 5-fluorouracil (5-FU in the treatment of corneal intraepithelial neoplasia (CIN, and conjunctival squamous cell carcinoma (SCC. Design: Prospective, noncomparative case series. Participants: Fifteen patients with histological evidence CIN or SCC of the conjunctiva and cornea were identified by tumor biopsy. Methods: All patients clinically evident of CIN, or SCC were evaluated, with maximum 30 months of follow-up were treated with pulsed dosing of 1% 5-FU. Treatment cycles were defined as four times per day for 4 days using the medication followed by 30 days without medication. The number of initial treatment was six cycles. Results: The mean age of the 15 patients was 50.8 years (range 25–78 years. Excision biopsy proved seven cases as CIN, and eight cases as locally invasive SCC. All patients remained disease free with a mean follow-up of 14.53 months (range 6-30 months. Additional chemotherapy was given after the initial treatment cycles, only for one case. 5-FU caused mild temporary local irritation, but no long-term intraocular or extra ocular complications. Conclusions: Adjuvant 1% topical 5-FU appears to be effective in the prevention of recurrence of conjunctival or corneal CIN and SCC after excision biopsy. Our results indicate that at least six cycles of topical 1% 5-FU is required to prevent local recurrence in the long term. It is well-tolerated and an effective method of treatment. No complications that would preclude use of our dose regimen were noted.Keywords: chemotherapy, fluorouracil, neoplasia, treatment cycles

  3. Sobredentadura total superior implantosoportada

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    Luis Orlando Rodríguez García

    2010-06-01

    Full Text Available Se presenta un caso de un paciente desdentado total superior, rehabilitado en la consulta de implantología de la Clínica "Pedro Ortiz" del municipio Habana del Este en Ciudad de La Habana, Cuba, en el año 2009, mediante prótesis sobre implantes osteointegrados, técnica que se ha incorporado a la práctica estomatológica en Cuba como alternativa al tratamiento convencional en los pacientes desdentados totales. Se siguió un protocolo que comprendió una fase quirúrgica, procedimiento con o sin realización de colgajo y carga precoz o inmediata. Se presenta un paciente masculino de 56 años de edad, que acudió a la consulta multidisciplinaria, preocupado, porque se le habían elaborado tres prótesis en los últimos dos años y ninguna reunía los requisitos de retención que él necesitaba para sentirse seguro y cómodo con las mismas. El resultado final fue la satisfacción total del paciente, con el mejoramiento de la calidad estética y funcional.

  4. Tectonic corneal graft for conjunctival rhinosporidiosis with scleral melt

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    Pushpa Jacob

    2011-01-01

    Full Text Available A 16 year old girl presented with irritation and watering of the right eye for 3 months. On examination, the superior perilimbal sclera was ectatic with incarcerated uveal tissue covered by conjunctiva. The conjunctiva showed discreet, yellow white mucoid spots. Excision biopsy of the conjunctiva showed subepithelial spherules of sporangia containing numerous endospores, suggestive of rhinosporidiosis. Diathermy was applied to flatten the staphyloma. The ectatic area was covered with a corneal patch graft. The patient was started on prednisolone acetate eye drops and oral dapsone for 6 months. Corneal graft was well incorporated and conjunctivalized by 3 months. Since the graft was not seen within the palpebral aperture, there was good cosmetic result. The corneal graft had the added advantage of transparency which allowed visualization of the underlying tissue to diagnose early recurrence. There was no recurrence at 6 months.

  5. Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

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    Natalia Pimentel Moreno

    2014-12-01

    Full Text Available Purpose: To study the aerobic bacterial microbiota of the conjunctiva in diabetic patients with regard to the management of diabetes, assessed using glycated hemoglobin levels. Methods: A cross-sectional study was conducted using conjunctival smears of diabetic patients from both sexes and with different ages, residing in two different Brazilian cities (Sorocaba and Rio Branco. A control group of non-diabetic patients was also included. The diabetic patients were considered to have controlled diabetes when their glycated hemoglobin level was ≤7% and blood glucose level was ≤126 mg/dL. Patients with non-controlled diabetes were those with glycated hemoglobin levels >7% and blood glucose levels >126 mg/dL. The samples obtained were inoculated in Brain-Heart Infusion broth and in culture media for aerobic bacteria (blood and chocolate agars; bacterial growth was evaluated in a microbiology laboratory. Results: A total of 120 eyes of 120 patients were included in the present study. The percentage of cultures in which bacterial growth was observed was greater in diabetic patients, although the difference was not statistically significant (p=0.103. There was a greater trend toward bacterial growth in the conjunctiva of diabetic patients with altered fasting blood glucose. There was no difference in the frequency of bacterial growth on the conjunctiva between diabetic patients with normal or altered glycated hemoglobin levels. In Sorocaba, conjunctival bacterial growth was similar to that observed in Rio Branco. The microorganism most frequently detected in the present study was Staphylococcus epidermidis, followed by Staphylococcus aureus, Proteus mirabilis, and Escherichia coli. Conclusion: There was no difference between diabetic patients with normal or altered glycated hemoglobin levels. The microorganisms found were similar to those found in studies investigating the conjunctival bacterial flora of diabetic and non-diabetic patients.

  6. Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil.

    Science.gov (United States)

    Moreno, Natalia Pimentel; Moreno, Renaldo Duarte; Sousa, Luciene Barbosa

    2014-01-01

    To study the aerobic bacterial microbiota of the conjunctiva in diabetic patients with regard to the management of diabetes, assessed using glycated hemoglobin levels. A cross-sectional study was conducted using conjunctival smears of diabetic patients from both sexes and with different ages, residing in two different Brazilian cities (Sorocaba and Rio Branco). A control group of non-diabetic patients was also included. The diabetic patients were considered to have controlled diabetes when their glycated hemoglobin level was ≤7% and blood glucose level was ≤126 mg/dL. Patients with non-controlled diabetes were those with glycated hemoglobin levels >7% and blood glucose levels >126 mg/dL. The samples obtained were inoculated in Brain-Heart Infusion broth and in culture media for aerobic bacteria (blood and chocolate agars); bacterial growth was evaluated in a microbiology laboratory. A total of 120 eyes of 120 patients were included in the present study. The percentage of cultures in which bacterial growth was observed was greater in diabetic patients, although the difference was not statistically significant (p=0.103). There was a greater trend toward bacterial growth in the conjunctiva of diabetic patients with altered fasting blood glucose. There was no difference in the frequency of bacterial growth on the conjunctiva between diabetic patients with normal or altered glycated hemoglobin levels. In Sorocaba, conjunctival bacterial growth was similar to that observed in Rio Branco. The microorganism most frequently detected in the present study was Staphylococcus epidermidis, followed by Staphylococcus aureus, Proteus mirabilis, and Escherichia coli. There was no difference between diabetic patients with normal or altered glycated hemoglobin levels. The microorganisms found were similar to those found in studies investigating the conjunctival bacterial flora of diabetic and non-diabetic patients.

  7. Microbiological efficacy of lomefloxacin and other drug's regarding microorganisms isolated from the human conjunctiva Atividade biocida da lomefloxacina em relação aos microorganismos isolados de conjuntiva humana

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    Ana Luísa Hofling-Lima

    2001-04-01

    Full Text Available Purpose: To evaluate and compare the in vitro susceptibility of human conjunctival bacterial isolates to various antimicrobial agents, including lomefloxacin, other fluoroquinolones (ciprofloxacin, norfloxacin, and ofloxacin, aminoglycosides (gentamicin, tobramycin, and amicacin, and cephalosporin (cephalothin. Methods: Antibiotic susceptibility tests conducted over a period of 27 months with 613 bacterial isolates from the conjunctiva were retrospectively analyzed. Results: In relation to the total number of positive isolates, the fluoroquinolones showed greater in vitro effectiveness than the other analyzed antibiotics. All bacterial isolates showed significantly higher susceptibility to ciprofloxacin than to lomefloxacin. Conclusion: The fluoroquinolones are not only equally effective against all conjunctival bacterial isolates, but they also show superior antimicrobial activity in comparison to aminoglycosides and cephalothin. These results suggest that fluoroquinolones, such as lomefloxacin, can be beneficially prescribed for conjunctival infections and also as prophylaxis in ocular surgery.Objetivo: Avaliar e comparar a atividade biocida in vitro de bactérias isoladas da conjuntiva humana à lomefloxacina, a outras fluorquinolonas (ciprofloxacina, norfloxacina e ofloxacina, aos aminoglicosídeos (gentamicina, tobramicina e amicacina e à cefalosporina (cefalotina. Métodos: Foram analisados retrospectivamente os resultados dos antibio-gramas realizados no período de 27 meses com 613 bactérias isoladas da conjuntiva. Resultados: A eficácia in vitro das quinolonas de acordo com o total dos isolamentos positivos foi superior em relação aos outros antibióticos avaliados. A suscetibilidade do total de bactérias à ciprofloxacina foi significantemente mais alta quando comparada à lomefloxacina. Conclusão: Os resultados praticamente equivalentes da suscetibilidade de bactérias isoladas da conjuntiva a fluorquinolonas, associado

  8. 正常人球结膜激光共焦显微镜下的形态学分析%Morphology of normal bulbar conjunctiva under in vivo confocal microscopy

    Institute of Scientific and Technical Information of China (English)

    宋影慧; 王丽娅; 荆洋; 张月琴; 李金

    2011-01-01

    conjunetiva cells under the in vivo confocal microscopy. Methods Laser scanning confocal microscopy was used to examine the morphological characteristics of the bulbar conjunetiva in 21 eyes of 15 healthy volunteers.The parameters of confocal microscopy were as follows:resolution 1 μm,wave length 670 nm,field range 400 μm×400 μm.The epithelial cell numbers,dendritics cells density and goblet cells density from superior,inferonasal,nasal and temporal bulbar conjunctiva were calculated respectively and compared and imaged by the HRT3 Rostock Cornea Modual. Results The superficial epithelial cells of the bulbar conjunctiva was seen with the small cell nuclei and blur border.The borders of basal epithelial celt were clearly visible without cell nuclei.The presumed goblet cell presented with a large hyperreflective oval-shaped cell with relatively homogeneous brightness,crowed in groups or mainly dispersed.The orfices at the epithelial surface represented the goblet cells,showing some open and expel contents.The dendritic cell appeared to be hyperreflective corpuscular particles with visible processes among conjunetival epithelial cells.A few dense white fiber meshwork was exhibited in conjunctival stroma with the traverse blood vessels containing cellular elements.The superficial and basal epithelial cell densities were 2556±692and 2985±376 cells/mm2 respectively,and overall goblet and mature dendritic cells densities were 77±39 and 26±35 cells/mm2 respectively.Significant differences were proved in globet cell density and dendritic density among different conjunetival zones(P=0.001,P=0. 000),however,the alteration of conjunetival epithelium cells was insignificant in different area(P=0.204,P=0.130).Conclusion Confocal microscopy is a useful tool for the study of morphology of human bulbar conjunctiva cells in vivo.which offer a valuable aid in the diagnosis of ocular surface disease.

  9. Reconstrucción total del párpado superior mediante colgajo frontal Whole repair made in the upper eyelid using a frontal flap

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    Yamilé León Rodríguez

    2009-12-01

    Full Text Available Los pacientes que han sido sometidos a resecciones quirúrgicas por cáncer, que han sufrido lesiones por quemaduras de espesor total o traumas avulsivos con pérdida extensa de tejidos que engloban la totalidad del párpado superior, acuden con relativa frecuencia a consulta por presentar la cornea expuesta, y dicha exposición resulta en ulceraciones, cicatriz y ceguera. En estos pacientes se observa una gran insatisfacción por el inconveniente que representa no poder usar una prótesis ocular y algo no menos importante, el gran defecto estético. Se presenta el caso de un paciente del sexo masculino, de 30 años de edad, que sufrió múltiples lesiones por el estallido de un artefacto explosivo, con pérdida total del párpado superior derecho y enucleación ocular. Se le realizó reconstrucción palpebral total mediante el colgajo dermograso frontal y se obtuvieron buenos resultados estéticos.Patients underwent to surgical resections from cancer and whole thickness burn lesions or avulsion traumata with an extent loss of tissues which shape the upper eyelid, came with a relative frequency to consultation due to corneal exposition and this exposition resulting in ulcerations, scar, and blindness. These patients are very unsatisfied because they can not use of an ocular prosthesis, and something less important, the big aesthetic defect. Authors present the case of a male patient aged 30 with multiple lesions from explosion of an explosive artifact with loss of right upper eyelid and ocular enucleation. A total palpebral reconstruction was performed using a frontal dermal fatty flap with good aesthetic results.

  10. Alterações da microbiota conjuntival e palpebral após uso tópico de lomefloxacina e tobramicina na cirurgia de catarata e cirurgia refrativa

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    Höfling - Lima Ana Luisa

    2002-01-01

    Full Text Available Objetivo: Avaliar as alterações da microbiota conjuntival e palpebral após o uso tópico de colírios de lomefloxacina ou tobramicina a 0,3% no preparo de pacientes a serem submetidos à cirurgia de catarata e cirurgia refrativa e avaliar a sensibilidade das bactérias isoladas da conjuntiva e pálpebra a estes antibióticos. Métodos: Realizou-se um estudo prospectivo de análise da microbiota conjuntival e palpebral de pacientes submetidos à cirurgia de catarata e cirurgia refrativa (PRK ou LASIK. O estudo da microbiota conjuntival e palpebral foi realizado antes das cirurgias, sem uso de agentes para profilaxia, no período pós-operatório durante o uso de profilaxia, e após a suspensão dos antibióticos. Resultados: O uso tópico de tobramicina e lomefloxacina reduziu o número de colheitas positivas na conjuntiva e pálpebra nos indivíduos submetidos à cirurgia de catarata e cirurgia refrativa. Em ambos os grupos de pacientes ocorreu maior resistência dos microrganismos à tobramicina. No grupo submetido à cirurgia de catarata, pacientes tratados profilaticamente com tobramicina tiveram uma recuperação da microbiota mais lenta após a suspensão do antibiótico do que com a lomefloxacina, ocorrendo o oposto no grupo submetido à cirurgia refrativa. Conclusão: Tanto a lomefloxacina quanto a tobramicina foram eficazes em diminuir o número de culturas positivas da conjuntiva e da pálpebra enquanto estavam sendo administrados, sendo esta diminuição mais acentuada na conjuntiva. Houve maior resistência à tobramicina na maioria das colheitas realizadas. A lomefloxacina apresentou número menor de bactérias resistentes do que a tobramicina durante o uso da antibioticoterapia tópica profilática. O uso de antibiótico reduziu o número de amostras positivas.

  11. 75 FR 28542 - Superior Resource Advisory Committee

    Science.gov (United States)

    2010-05-21

    ... orient the new Superior Resource Advisory Committee members on their roles and responsibilities. DATES... of the roles and responsibilities of the Superior Resource Advisory Committee members; Election of... Forest Service Superior Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice...

  12. Biofilms of Candida spp. from the ocular conjunctiva of horses with reduced azole susceptibility: a complicating factor for the treatment of keratomycosis?

    Science.gov (United States)

    Brilhante, Raimunda Sâmia Nogueira; Bittencourt, Paula Vago; de Souza Collares Castelo-Branco, Débora; de Melo Guedes, Glaucia Morgana; de Oliveira, Jonathas Sales; Alencar, Lucas Pereira; de Aguiar Cordeiro, Rossana; Pinheiro, Mariana; Nogueira-Filho, Evilázio Fernandes; de Aquino Pereira-Neto, Waldemiro; Sidrim, José Júlio Costa; Rocha, Marcos Fábio Gadelha

    2017-04-18

    This study aimed to assess the biofilm-forming ability of Candida spp. from the ocular conjunctiva of horses and to investigate the antifungal susceptibility of these biofilms. Initially, the biofilm-forming ability of 15 strains was assessed by crystal violet staining, which reveals the fungal biomass adhered to the polystyrene plates, and scanning electron microscopy. Then, the minimum inhibitory concentrations (MICs) of amphotericin B, fluconazole, itraconazole, and caspofungin were initially determined against strains in planktonic form. Afterward, antifungal susceptibility of mature biofilms was evaluated by exposing them to 10 × MIC and 50 × MIC of the tested drugs, followed by the assessment of their metabolic activity, using the oxidoreduction indicator XTT. Results were analyzed through ANOVA and Tukey's post-test, and P-values below 5% led to significant conclusions. Eight strains produced biofilms and were classified as strong (1/15), moderate (3/15) and weak (4/15) producers, according to the amount of crystal violet retained by the adhered fungal biomass. Biofilm metabolic activity of one C. tropicalis did not decrease after exposure to the tested antifungals, while biofilm metabolic activity of five strains was reduced by amphotericin B, but not the other drugs. One C. parapsilosis sensu stricto and one C. glabrata showed significant reduction in biofilm metabolic activity after exposure to fluconazole, itraconazole, and caspofungin, but not amphotericin B. The results demonstrate that Candida from the ocular conjunctiva of horses can pose as a risk to animal health as they are capable of forming biofilms, which are commonly involved in fungal keratitis. © 2017 American College of Veterinary Ophthalmologists.

  13. [The superior laryngeal nerve and the superior laryngeal artery].

    Science.gov (United States)

    Lang, J; Nachbaur, S; Fischer, K; Vogel, E

    1987-01-01

    Length, diameter and anastomoses of the nervus vagus and its ganglion inferius were measured 44 halved heads. On the average, 8.65 fiber bundles of the vagus nerve leave the retro-olivary area. In the area of the jugular foramen is the near superior ganglion of the 10th cranial nerve. In this area were found 1.48 (mean value) anastomoses with the 9th cranial nerve. 11.34 mm below the margo terminalis sigmoidea branches off the ramus internus of the accessory nerve which has a length of 9.75 mm. Further anastomoses with the 10th cranial nerve were found. The inferior ganglion of the 10th nerve had a length of 25.47 mm and a diameter of 3.46 mm. Five mm below the ganglion the 10th nerve had a width of 2.9 and a thickness of 1.5 mm. The mean length of the superior sympathetic ganglion was 26.6 mm, its width 7.2 and its thickness 3.4 mm. In nearly all specimens anastomoses of the superior sympathetic ganglion with the ansa cervicalis profunda and the inferior ganglion of the 10th cranial nerve were found. The superior laryngeal nerve branches off about 36 mm below the margo terminalis sigmoidea. The width of this nerve was 1.9 mm, its thickness 0.8 mm on the right and 1.0 mm on the left side. The division in the internal and external rami was found about 21 mm below its origin. Between the n. vagus and thyreohyoid membrane the ramus internus had a length of 64 mm, the length of external ramus between the vagal nerve and the inferior pharyngeal constrictor muscle was 89 mm. Its mean length below the thyreopharyngeal part was 10.7 mm, 8.6 branchlets to the cricothyroid muscle were counted. The superior laryngeal artery had its origin in 80% of cases in the superior thyroideal artery, in 6.8% this vessel was a branch of the external carotid artery. Its average outer diameter was 1.23 mm on the right side and 1.39 mm on the left. The length of this vessel between its origin and the thyreohyoid membrane was 34 mm. In 7% on the right side and in 13% on the left, the superior

  14. Etiología de las bolsas grasas palpebrales: Estudio anatómico relacionado con el envejecimiento y actitudes terapéuticas congruentes Inferior palpebral fat bags etiology: Anatomical study related to aging and congruent therapeutical attitudes

    Directory of Open Access Journals (Sweden)

    L. De la Cruz Ferrer

    2012-06-01

    Full Text Available Las bolsas grasas palpebrales inferiores son de las alteraciones más frecuentemente vistas en las consultas de Cirugía Estética. Realizamos una revisión de su controvertida etiología en relación con la anatomía orbitaria y los cambios producidos por en el proceso del envejecimiento de los tejidos orbitarios y exponemos las alternativas terapéuticas que actualmente consideramos más congruentes y fisiológicas y que han demostrado unos resultados consistentes.Inferior palpebral fat bags are among the most common causes of Aesthetic Surgery consultation. We review their controversial etiology related to the orbital anatomy and the changes that take place in the orbital tissues in the process of aging. Based on these hypotheses the authors describe the treatment alternatives which they consider most congruent and physiologic and that have proven consistent results.

  15. Retracción palpebral en patología de graves : Cirugía vs tratamiento con toxina botulínica. Revisión bibliográfica

    OpenAIRE

    Luna, Laura Lorena

    2016-01-01

    Se realizó una completa revisión bibliográfica de la patología de Graves, poniendo especial atención en la orbitopatía y sus manifestaciones oftalmológicas. Se hizo especial mención de la retracción palpebral que es la manifestación más frecuente de la orbitoptía buscando comparar, dependiendo de cada paciente y en que fase de la misma se encuentre, cual de estos dos tratamientos es el más adecuado: si una reparación quirúrgica o el tratamiento con toxina botulínica. Departamento de Cirugí...

  16. What are Millian Qualitative Superiorities?

    Directory of Open Access Journals (Sweden)

    Jonathan Riley

    2008-04-01

    Full Text Available In an article published in Prolegomena 2006, Christoph Schmidt-Petri has defended his interpretation and attacked mine of Mill’s idea that higher kinds of pleasure are superior in quality to lower kinds, regardless of quantity. Millian qualitative superiorities as I understand them are infinite superiorities. In this paper, I clarify my interpretation and show how Schmidt-Petri has misrepresented it and ignored the obvious textual support for it. As a result, he fails to understand how genuine Millian qualitative superiorities determine the novel structure of Mill’s pluralistic utilitarianism, in which a social code of justice that distributes equal rights and duties takes absolute priority over competing considerations. Schmidt-Petri’s own interpretation is a non-starter, because it does noteven recognize that Mill is talking about different kinds of pleasant feelings, such that the higher kinds are intrinsically more valuable than the lower. I conclude by outlining why my interpretation is free of any metaphysical commitment to the “essence” of pleasure.

  17. Isolated superior mesenteric artery dissection

    Directory of Open Access Journals (Sweden)

    Lalitha Palle

    2010-01-01

    Full Text Available Isolated superior mesenteric artery (SMA dissection without involvement of the aorta and the SMA origin is unusual. We present a case of an elderly gentleman who had chronic abdominal pain, worse after meals. CT angiography, performed on a 64-slice CT scanner, revealed SMA dissection with a thrombus. A large artery of Drummond was also seen. The patient was managed conservatively.

  18. A escrita no Ensino Superior

    Directory of Open Access Journals (Sweden)

    Maria Conceição Pillon Christofoli

    2013-01-01

    Full Text Available http://dx.doi.org/10.5902/198464445865 O presente artigo trata de apresentar resultados oriundos de pesquisa realizada no Ensino Superior, enfocando a escrita em contextos universitários. Depoimentos por parte dos acadêmicos evidenciam certa resistência ao ato de escrever, o que acaba muitas vezes distanciando o sujeito da produção de um texto. Assim sendo, mesmo que parciais, os resultados até então analisados dão conta de que: pressuposto 1 – há ruptura da ideia de coerência entre o que pensamos, o que conseguimos escrever, o que entende nosso interlocutor; pressuposto 2 – a autocorreção de textos como exercício de pesquisa é imprescindível para a qualificação da escrita; pressuposto 3 – os diários de aula representam rico instrumento para a qualificação da escrita no Ensino Superior; pressuposto 4 – há necessidade de que o aluno do Ensino Superior escreva variados tipos de escrita, ainda que a universidade cumpra com seu papel, enfatizando a escrita acadêmica; pressuposto 5 – o trabalho com a escrita no Ensino Superior deve enfatizar os componentes básicos da expressão escrita: o código escrito e a composição da escrita. Palavras-chave: Escrita; Ensino Superior; formação de professores.

  19. 20G Vitrectomy conjunctiva micro-incision technique clinical application%20G玻璃体切割结膜微创切口技术应用分析

    Institute of Scientific and Technical Information of China (English)

    王文战; 郝娟; 杨惠春; 晁晓蕊

    2010-01-01

    Objective To evaluate the curative effect of clinical application of 20-gauge (20G) vitrectomy conjunctiva micro-incision technique.Methods The clinical data of 76 patients with vitreous retinal disease patients treated by the 20G vitrectomy conjunctiva micro-incision technique were retrospectively analyzed.Operative incision was divided into conjunctiva micro-incision group and convention vitrectomy group.When the operation was over-peripheral retina,only the incision for vitrectomy and light probe in conjunctiva micro-incision was sutured.All patients were followed up by 2-4months.Incision for bulbar conjunctiva and sclerotic was sutured in conventional vitrectomy.Conjunctival congestion,wound healing,intra-ocular tension,and operation running time were observed after operation.Results The mean operation time needed in conjunctiva micro-incision groups was 49minutes,while that in the conventional group was 61 minutes.There was statistical significance in the mean time of operation between two gronps.Bulbar conjunctiva superficies was smooth,sclerotic incision close was well,congestion and edema vanished in conjunctiva micro-incision group,while there was no significant difference in intra-ocular tension after operation between two groups.Conclusions Vitrectomy incision by using conjunctiva micro-incision has many advantages such as short operation time,micro-invasion and rapid recovery.It is worthy to be popularized.%目的 探讨20G玻璃体切割术(简称玻切)结膜微创切口技术临床应用的疗效.方法 回顾性分析76例76只眼应用20G结膜微创切口技术行玻切术治疗玻璃体视网膜疾病患者的临床资料.手术切口分为结膜微创切口组及常规玻切组.结膜微创切口组手术结束时不缝合球结膜切口及灌注系统巩膜穿刺口,仅缝合玻切头及光导纤维头巩膜切口.而常规玻切组则用8-0可吸收缝线8字缝合玻切头、光导纤维、灌注系统巩膜切口及对位缝合球

  20. Corrección de ptosis palpebral por la incisión de blefaroplastia Upper eyelid ptosis treatment using blepharoplasty incision

    OpenAIRE

    A. Novo Torres; J.F. Salvador Sanz; E. Lorda Barraguer; C. Laredo Ortiz

    2006-01-01

    Se entiende por blefaroptosis el nivel anormalmente bajo del párpado superior durante la mirada directa. Los mejores resultados se obtienen con las técnicas de resección o avance del músculo elevador o su aponeurosis, siempre que el elevador posea una función adecuada. Nuestra intención es presentar una modificación a la técnica de Blaskovics para la corrección de blefaroptosis moderadas, con buena función del elevador Presentamos una serie de 10 casos donde se utilizó una variante de la oper...

  1. Pensamiento Superior y Desarrollo Territorial

    Directory of Open Access Journals (Sweden)

    Víctor Manuel Racancoj Alonzo

    2015-04-01

    Full Text Available Esta reflexión pretende explicar el papel, fundamental, que juega el pensamiento superior, en la formulación y la práctica de modelos de desarrollo territorial local; para que contribuyan de forma sustantiva, en la transformación de las condiciones socioeconómicas adversas que hoy viven comunidades indígenas y rurales de muchos países, como Guatemala, situación que puede resumirse en altos índices de pobreza y desnutrición. Pero, el pensamiento superior, debe ser competencia de la población con pertenencia a lo local, pues si y solo si esta condición existe, se dará validez y viabilidad al desarrollo territorial. Para alcanzar competencias de pensamiento superior, en los espacios locales, se tiene que superar obstáculos en el modelo de universidad, que hoy estamos familiarizados a ver y pensar; modelos que tienen las características de: herencia colonial, disfunción con la problemática económica, cultural, social y política de la sociedad y la negación de los saberes ancestrales.

  2. Superior sulcus tumors (Pancoast tumors).

    Science.gov (United States)

    Marulli, Giuseppe; Battistella, Lucia; Mammana, Marco; Calabrese, Francesca; Rea, Federico

    2016-06-01

    Superior Sulcus Tumors, frequently termed as Pancoast tumors, are a wide range of tumors invading the apical chest wall. Due to its localization in the apex of the lung, with the potential invasion of the lower part of the brachial plexus, first ribs, vertebrae, subclavian vessels or stellate ganglion, the superior sulcus tumors cause characteristic symptoms, like arm or shoulder pain or Horner's syndrome. The management of superior sulcus tumors has dramatically evolved over the past 50 years. Originally deemed universally fatal, in 1956, Shaw and Paulson introduced a new treatment paradigm with combined radiotherapy and surgery ensuring 5-year survival of approximately 30%. During the 1990s, following the need to improve systemic as well as local control, a trimodality approach including induction concurrent chemoradiotherapy followed by surgical resection was introduced, reaching 5-year survival rates up to 44% and becoming the standard of care. Many efforts have been persecuted, also, to obtain higher complete resection rates using appropriate surgical approaches and involving multidisciplinary team including spine surgeon or vascular surgeon. Other potential treatment options are under consideration like prophylactic cranial irradiation or the addition of other chemotherapy agents or biologic agents to the trimodality approach.

  3. Microbiota bacteriana aeróbia da conjuntiva de doadores de córnea Aerobic bacterial microbiota of the conjunctiva of cornea donors

    Directory of Open Access Journals (Sweden)

    Paula Fontana Lorenzini

    2007-03-01

    Full Text Available OBJETIVOS: Determinar a microbiota bacteriana aeróbia da conjuntiva de doadores de córnea e seu padrão de suscetibilidade a antibióticos; verificar o número de córneas utilizadas para transplante e a média de tempo de preservação em solução preservante com gentamicina e estreptomicina; traçar o perfil dos doadores e receptores de córnea. MÉTODOS: Espécimes clínicos foram colhidos de saco inferior da conjuntiva de ambos os olhos, de 40 doadores de córnea. As amostras foram inoculadas em ágar sangue azida, ágar chocolate e ágar MacConkey e o antibiograma foi realizado pelo método de Kirby-Bauer. RESULTADOS: A freqüência de cultura positiva da conjuntiva de doadores de córnea foi de 72,5%, sendo que Gram-positivos totalizaram 81,6% e apenas 18,4% das amostras foram identificadas como Gram-negativos. Vancomicina inibiu 100% dos Gram-positivos, ao passo que a sensibilidade dos Gram-negativos à gentamicina foi de 53,8% e à estreptomicina foi de 30%. O sexo masculino predominou entre os doadores e receptores, a média de tempo entre o óbito e a enucleação foi de 2h e a de preservação em solução preservante com gentamicina e estreptomicina foi de 7 dias. Neoplasia e mais de uma causa associada foram as causas de óbito mais freqüentes. O ceratocone foi a principal indicação para transplante (51,7%. CONCLUSÕES: Staphylococcus coagulase negativo foi o microrganismo com o maior número de isolamentos, apresentando sensibilidade variada aos antimicrobianos. A quantidade de córneas utilizadas para transplante foi bastante inferior em relação ao total de captações. O perfil dos doadores e receptores de córnea mostrou-se heterogêneo para grande parte das variáveis analisadas.PURPOSE: To determine aerobic bacterial microbiota of the conjunctiva of cornea donors and its patterns of susceptibility to antibiotics; verify the number of corneas used for transplant and the average time of preservation in solutions with

  4. Entidades fiscalizadoras superiores y accountability

    OpenAIRE

    Estela Moreno, María

    2016-01-01

    OBJETIVOS DE LA TESIS: El objetivo general del trabajo es establecer el nivel de eficacia de las Entidades Fiscalizadoras Superiores (EFS) como agencia asignada y herramienta de accountability horizontal, a través de la valoración de su diseño institucional y de la calidad de sus productos finales, los informes de auditoría, estableciéndose los siguientes objetivos específicos: 1. Relevar las nociones de accountability, actualizando el Estado del Arte de la cuestión. 2. Analizar la ...

  5. The sentence superiority effect revisited.

    Science.gov (United States)

    Snell, Joshua; Grainger, Jonathan

    2017-11-01

    A sentence superiority effect was investigated using post-cued word-in-sequence identification with the rapid parallel visual presentation (RPVP) of four horizontally aligned words. The four words were presented for 200ms followed by a post-mask and cue for partial report. They could form a grammatically correct sentence or were formed of the same words in a scrambled agrammatical sequence. Word identification was higher in the syntactically correct sequences, and crucially, this sentence superiority effect did not vary as a function of the target's position in the sequence. Cloze probability measures for words at the final, arguably most predictable position, revealed overall low values that did not interact with the effects of sentence context, suggesting that these effects were not driven by word predictability. The results point to a level of parallel processing across multiple words that enables rapid extraction of their syntactic categories. These generate a sentence-level representation that constrains the recognition process for individual words, thus facilitating parallel word processing when the sequence is grammatically sound. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Cataract surgery with small incision under the limbal conjunctiva%结膜下角膜缘潜行小切口手法白内障手术

    Institute of Scientific and Technical Information of China (English)

    王文战; 陈晓君; 张效房

    2011-01-01

    目的 探讨结膜下角膜缘潜行小切口手法白内障摘出人工晶状体植入术的效果和并发症.方法 于9~12点位间角膜缘的角膜与结膜结合处后方0.5 mm,以45°角斜向切开结膜角膜组织,达1/2角膜厚度,切口宽5.5~6.0 mm.向前在透明角膜内制作隧道,长约2.0 mm.穿刺进入前房.常规连续环形撕囊或截囊,然后借助注水圈匙手法娩核,囊袋内植入人工晶状体.观察1210例1293眼.术前术后测视力及角膜曲率,并做裂隙灯显微镜检查及A/B超检查.随访4~6周.结果 视力:手术前:光感~0.15,手术后:0.05~1.0.角膜曲率:手术前:K1=(43.99±1.83)D,K2=(43.83±2.06)D,手术后2周:K1=(45.08±2.30)D,K2=(44.07±2.86)D(u检验:P>0.5).意外撞伤致切口裂开并虹膜脱出6例6眼,占0.46%.角膜水肿及前房渗出均较轻微,无前房积血、人工晶状体移位或感染等并发症.手术时间一般为5~8 min.结论 结膜下角膜缘潜行小切口手法白内障摘出人工晶状体植入术操作简单,易于掌握,且手术时间短伤口愈合快,并发症少.%Objective To explore the effects and complications of manual cataract extraction and IOL implantation with small incision under the limbal conjunctiva.Methods Cornea conjunctiva tissue Was incised with 45°beveled direction,0.5 mm after the junction of limbus and conjunctiva from 9'clock to 12'clock,with depth of 1/2 cornea and width of 5.5~6.0 mm.The tunnel incision Was produced up to clear cornea with length of 2.0 mm and then punctured into the anterior chamber.After continuous curvilinear capsulotomy or capsulorhexis and manual expulsion the nuclear,IOL Was implanted.1293 eyes of 1210 pa-tients were observed,visual acuity,corneal curvature,slit lamp microscope examination and A/B ultrasonic inspection were recorded before and after surgery.The patients were followed up for 4 to 6 weeks.Results The visual acuity:light pemepfion to 0.15 preoperatively and 0.05 to 1.0 postoperatively

  7. Detection of mucus glycoconjugates in human conjunctiva by using the lectin colloidal gold technique in TEM. I. A quantitative study in normal subjects.

    Science.gov (United States)

    Versura, P; Maltarello, M C; Bonvicini, F; Caramazza, R; Laschi, R

    1986-08-01

    We applied a specific cytochemical reaction to characterize the glycoconjugates produced by goblet and non-goblet epithelial cells of normal human conjunctiva. For this purpose we utilized the lectins, proteins of vegetal origin, which are extremely sensitive in binding glycosidic residues. In particular, we used WGA, PNA, SBA and ConA conjugated with colloidal gold as ultrastructural marker for Transmission Electron Microscopy. This technique allowed us also to perform a quantitative analysis, by counting colloidal gold particles present on mucus granules. In this way we analyzed the content both of goblet and non-goblet epithelial cells. In the former, WGA, PNA, SBA and ConA receptors, here reported in decreasing density, were present. In the latter WGA was always positive, SBA and PNA sometimes were negative, ConA was always negative. We speculate the different contribution to mucus production by these two sources may be important in evaluating tear film stability alterations occurring in those diseases in which non-goblet epithelial cell vesicles increase.

  8. 丝裂霉素C治疗眼部手术后结膜植入性囊肿的临床观察%Clinical observation of Mitomycin C in curing implantantion cyst of conjunctiva after operation

    Institute of Scientific and Technical Information of China (English)

    孟凡华

    2012-01-01

    OBJECTIVE To observe the clinical efficacy of Mitomycin C in treating implantation cyst of conjunctiva after operation. METHODS Twenty-eight cases of implantation cyst of conjunctiva were given drainage through marginal incision and cleaned with 0.02% Mitomycin C. RESULTS Followed up for 3 months to 2 years, 28 cases were all cured. CONCLUSIONS Mitomycin C is a simple and efficient application in curing implantation cyst of conjunctiva.%目的 探究丝裂霉素C治疗眼部手术后结膜植入性囊肿的治疗效果.方法 对28例眼部手术后发生的球结膜植入性囊肿,采取囊肿一侧边缘切口放液,而后用0.02%丝裂霉素C擦拭囊壁治疗.结果 随访3个月~2年,28例患者全部治愈.结论 丝裂霉素C治疗结膜植入性囊肿简单有效,适合临床使用.

  9. Fenômeno de Marcus Gunn: diagnóstico diferencial das ptoses palpebrais na criança Marcus Gunn Phenomenon: differential diagnosis of palpebral ptoses in children

    Directory of Open Access Journals (Sweden)

    Marcia R. F. Torres

    2004-06-01

    Full Text Available OBJETIVO: Este trabalho teve por objetivo fazer uma revisão bibliográfica, relatar e discutir o caso clínico de um paciente com fenômeno de Marcus Gunn. DESCRIÇÃO: Criança de 5 anos de idade, sexo feminino, hígida. Nos primeiros meses de vida, em consulta de puericultura, foi detectada alteração no olho direito, que, a princípio, parecia tratar-se de estrabismo. Após consultas com vários oftalmologistas, não se alcançou um diagnóstico preciso. Já aos 4 anos de idade, após exame realizado por oftalmologista pediátrico, confirmou-se o diagnóstico do fenômeno de Marcus Gunn. O restante do exame físico, incluindo exame neurológico, estava normal. Por se tratar de ptose palpebral leve, sem outras patologias associadas, optou-se por uma conduta conservadora. COMENTÁRIOS: Este relato visa alertar os pediatras com relação ao fenômeno de Marcus Gunn, que ainda é pouco conhecido. A partir deste conhecimento, o pediatra poderá identificar o fenômeno, possibilitando o encaminhamento precoce para a abordagem de complicações ou condições associadas, além de diagnóstico diferencial com outros tipos de ptose palpebral.OBJECTIVE: The aim of this paper is to review existing literature on the subject and to report on and discuss a case of Marcus Gunn Phenomenon. DESCRIPTION: A five year-old female, otherwise a healthy patient, while still a few months old, was seen by a pediatrician who detected a disorder of the right eye, initially believed to be strabismus, at a follow-up childcare consultation. Several ophthalmologists failed to establish a precise diagnosis. After a pediatric ophthalmologist had examined the child at four years of age, a diagnosis of Marcus Gunn Phenomenon, otherwise known as jaw-winking phenomenon, was confirmed. Apart from this anomaly, physical, ophthalmological, and neurological examinations were normal. Since ptosis was mild and no association with strabismus, amblyopia or other conditions was

  10. 78 FR 21116 - Superior Supplier Incentive Program

    Science.gov (United States)

    2013-04-09

    ... Department of the Navy Superior Supplier Incentive Program AGENCY: Department of the Navy, DoD. ACTION... policy that will establish a Superior Supplier Incentive Program (SSIP). Under the SSIP, contractors that..., performance, quality, and business relations would be granted Superior Supplier Status (SSS). Contractors...

  11. superior en México

    Directory of Open Access Journals (Sweden)

    César Mureddu Torres

    2008-01-01

    Full Text Available El presente artículo desarrolla algunos de los retos que ha traído consigo el acceso a la información existente en la red de Internet y lo que ello supone. Se abordan principalmente las consecuencias de la presencia actual de una sociedad llamada del conocimiento, si se mantiene la confusión entre conocimiento e información. Por ello, la sola gestión de la información no puede ser tomada como definitoria respecto a la función de educación superior confiada a las universidades. Hacerlo sería cometer un error aún más grave que la confusión teórica entre los términos mencionados.

  12. Sistematización del colgajo musculocutáneo unipediculado de párpado superior en reconstrucción de párpado inferior, canto interno y externo

    Directory of Open Access Journals (Sweden)

    E. Martínez-Vera

    2015-03-01

    Full Text Available Están publicadas diferentes técnicas para la reconstrucción del párpado inferior y de los cantos interno y externo, algunas de ellas muy ingeniosas, pero a la vez muy complicadas, y sólo accesibles para cirujanos con amplia experiencia. Por lo tanto, simplificar y sistematizar una técnica sería muy útil para obtener un mejor resultado quirúrgico. El objetivo del presente trabajo es la sistematización de un colgajo musculocutáneo unipediculado del párpado superior, de 40 mm de largo y de 7, 10 o 15 mm de ancho, con pedículo en el canto palpebral externo o interno, para reconstruir total o parcialmente el párpado inferior, el canto interno o externo. Esta sistematización consiste en el diseño del colgajo teniendo en cuenta referencias anatómicas de la órbita fáciles de establecer. Para reconstruir la lamela o capa interna del párpado, que corresponde al tarso y conjuntiva, se utiliza un injerto de cartílago auricular o de septo nasal y para la capa externa del párpado, un colgajo musculocutáneo compuesto por piel y músculo orbicular del párpado superior. Con ello, se hace posible una fácil ejecución de la técnica quirúrgica, a la vez que se aprovecha al máximo la versatilidad del colgajo en la reconstrucción palpebral.

  13. Escuela Superior de Palos Verdes

    Directory of Open Access Journals (Sweden)

    Neutra, Richard J.

    1965-02-01

    Full Text Available Before initiating the building operations for the «Palos Verdes» School, the site was divided into two large horizontal surfaces, at different levels. The lower one served to accommodate the playing fields, a car park, the physical training building, and shop and ancillary buildings. On the higher of these two surfaces, and to the West of the access road, there is a car park and also the building and plot of ground devoted to agricultural technology, as well as the literary studies and general purpose buildings. As a complement to these, there is a series of blocks, arranged in parallel rows, which house the administrative offices, the art school, the craft's school, the general classrooms, and those devoted to higher education. The fascinating aspect of this school is the outstanding penetration of the architect's mind into the essential function of the project. Its most evident merit is the sense of comradeship and harmony that permeates the whole architectural manifold.Antes de construir el complejo escolar «Palos Verdes» se comenzó por crear, en el terreno, dos grandes mesetas a niveles diferentes. Sobre el inferior se organizaron: los campos de juegos, de deportes, un aparcamiento, el edificio para educación física y los destinados a tiendas y servicios. Sobre la meseta superior, al oeste de la vía de acceso, se dispuso un aparcamiento y el edificio y campo para adiestramiento agrícola; al este, otro aparcamiento, el edificio dedicado a materias literarias, y el destinado a usos múltiples. Completan las instalaciones de la escuela una serie de bloques paralelos: la administración, la escuela de arte, las clases de trabajos manuales, las aulas de enseñanzas generales, y las de los cursos superiores. Lo fascinante de este complejo escolar es la perfecta y magistral compenetración del arquitecto con el tema proyectado, y su mayor mérito, la sensación de cordialidad y armonía con el ambiente.

  14. Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease

    Science.gov (United States)

    Ogawa, Yoko; He, Hua; Mukai, Shin; Imada, Toshihiro; Nakamura, Shigeru; Su, Chen-Wei; Mahabole, Megha; Tseng, Scheffer C. G.; Tsubota, Kazuo

    2017-01-01

    Chronic graft-versus-host disease (cGVHD) is a major complication of hematopoietic stem cell transplantation. Dry eye disease is the prominent ocular sequel of cGVHD and is caused by excessive inflammation and fibrosis in the lacrimal glands. Heavy chain-Hyaluronan/Pentraxin 3 (HC-HA/PTX3) is a complex purified from human amniotic membrane (AM) and known to exert anti-inflammatory and anti-scarring actions. In this study, we utilized a mouse model of cGVHD to examine whether HC-HA/PTX3 could attenuate dry eye disease elicited by cGVHD. Our results indicated that subconjunctival and subcutaneous injection of HC-HA/PTX3 preserved tear secretion and conjunctival goblet cell density and mitigated inflammation and scarring of the conjunctiva. Such therapeutic benefits were associated with suppression of scarring and infiltration of inflammatory/immune cells in the lacrimal glands. Furthermore, HC-HA/PTX3 significantly reduced the extent of infiltration of CD45+ CD4+ IL-17+ cells, CD45+ CD34+ collagen I+ CXCR4+ fibrocytes, and HSP47+ activated fibroblasts that were accompanied by upregulation of collagen type Iα1, collagen type IIIα1 and NF-kB in lacrimal glands. Collectively, these pre-clinical data help prove the concept that subcutaneous and subconjunctival injection of HC-HA/PTX3 is a novel approach to prevent dry eye disease caused by cGVHD and allow us to test its safety and efficacy in future human clinical trials. PMID:28165063

  15. Bare sclera resection followed by mitomycin C and/or autograft limbus conjunctiva in the surgery for pterygium:a Meta-analysis

    Directory of Open Access Journals (Sweden)

    Tan Long

    2015-10-01

    Full Text Available AIM:Toevaluate the recurrence andcomplicationsafter bare sclera resection (BSR combined with mitomycin C (MMC treatment and/or autograft limbus conjunctiva (ALC in the surgery for pterygium.METHODS:Meta-analysis was used to evaluate the differences in patient outcomes between BSR of pterygium with or without MMC and/or ALC. All included studies were randomized trials of patients with pterygium who received BSR followed by MMC and/or ALC in the surgery. The recurrence of pterygium and other complications resulting from different treatments were extracted for analysis.RESULTS:Thirteen studies met the inclusion criteria. The recurrence of pterygium with intraoperative (IO MMC was higher than that with ALC (OR=2.38,95% confidence interval 1.45-3.91, I2=29%. Postoperative MMC resulted in an incidence of recurrence similar to that of ALC (OR=0.66, 95% confidence interval 0.30-1.42, I2=0%, and IO MMC treatment in combination with ALC produced similar patient outcomes to ALC alone (OR=0.41, 95% confidence interval 0.16-1.01, I2=16%. Other complications such as punctate epitheliopathy, scleral thinning and ischemia, irritation and persistent epithelium defect, were more common in patients in the MMC group as compared to those treated with ALC.CONCLUSION:The recurrence of pterygium with BSR followed by ALC is lower than that of BSR followed by MMC, and the incidence of other complications is lower. While ALC is a more effective strategy for treating pterygium, the quality of the ALC transplant should be considered when the patient has a history of glaucoma.

  16. Conjunctiva-associated lymphoid tissue (CALT reactions to antiglaucoma prostaglandins with or without BAK-preservative in rabbit acute toxicity study.

    Directory of Open Access Journals (Sweden)

    Hong Liang

    Full Text Available Conjunctiva-associated lymphoid tissue (CALT is closely associated with ocular surface immunity. This study investigated the effects of antiglaucoma prostaglandin analogs with or without benzalkonium chloride (BAK preservative on organized CALT using an acute toxic model. A total of 48 albino rabbits were used and seven groups of treatments were constituted. Solutions (50 µl of PBS, 0.02%BAK, (0.02%BAK+latanoprost, (0.015%BAK+travoprost, (0.005%BAK+bimatoprost, (BAK-freetravoprost preserved with the SofZia® system or (BAK-freetafluprost were instilled 15 times at 5-min intervals in both eyes. CALT changes were analyzed using in vivo confocal microscopy (IVCM, immunohistology in cryosections for detecting MUC-5AC+ mucocytes and CD45+ hematopoietic cells. Antiglaucoma eye drops stimulated inflammatory cell infiltration in the CALT, and seemed to be primarily related to the concentration of their BAK content. The CALT reaction after instillation of BAK-containing eye drops was characterized by inflammatory cell infiltration in the dome and intrafollicular layers and by cell circulation inside the lymph vessels. CD45 was strongly expressed in the CALT after instillation of all BAK-containing solutions at 4 h and decreased at 24 h. The number of MUC-5AC+ mucocytes around the CALT structure decreased dramatically after instillation of BAK-containing solutions. This study showed for the first time the in vivo aspect of rabbit CALT after toxic stimuli, confirming the concentration-dependent toxic effects of BAK. IVCM-CALT analysis could be a pertinent tool in the future for understanding the immunotoxicologic challenges in the ocular surface and would provide useful criteria for evaluating newly developed eye drops.

  17. Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells.

    Science.gov (United States)

    Massumi, Mohammad; Hoveizi, Elham; Baktash, Parvaneh; Hooti, Abdollah; Ghazizadeh, Leili; Nadri, Samad; Pourasgari, Farzaneh; Hajarizadeh, Athena; Soleimani, Masoud; Nabiuni, Mohammad; Khorramizadeh, Mohammad R

    2014-03-10

    Due to pluripotency of induced pluripotent stem (iPS) cells, and the lack of immunological incompatibility and ethical issues, iPS cells have been considered as an invaluable cell source for future cell replacement therapy. This study was aimed first at establishment of novel iPS cells, ECiPS, which directly reprogrammed from human Eye Conjunctiva-derived Mesenchymal Stem Cells (EC-MSCs); second, comparing the inductive effects of Wnt3a/Activin A biomolecules to IDE1 small molecule in derivation of definitive endoderm (DE) from the ECiPS cells. To that end, first, the EC-MSCs were transduced by SOKM-expressing lentiviruses and characterized for endogenous expression of embryonic markers Then the established ECiPS cells were induced to DE formation by Wnt3a/Activin A or IDE1. Quantification of GSC, Sox17 and Foxa2 expression, as DE-specific markers, in both mRNA and protein levels revealed that induction of ECiPS cells by either Wnt3a/Activin A or IDE1 could enhance the expression level of the genes; however the levels of increase were higher in Wnt3a/Activin A induced ECiPS-EBs than IDE1 induced cells. Furthermore, the flow cytometry analyses showed no synergistic effect between Activin A and Wnt3a to derive DE-like cells from ECiPS cells. The comparative findings suggest that although both Wnt3a/Activin A signaling and IDE1 molecule could be used for differentiation of iPS into DE cells, the DE-inducing effect of Wnt3a/Activin A was statistically higher than IDE1.

  18. Sobredentadura total superior implantosoportada Superior total overdenture on implants

    Directory of Open Access Journals (Sweden)

    Luis Orlando Rodríguez García

    2010-06-01

    Full Text Available Se presenta un caso de un paciente desdentado total superior, rehabilitado en la consulta de implantología de la Clínica "Pedro Ortiz" del municipio Habana del Este en Ciudad de La Habana, Cuba, en el año 2009, mediante prótesis sobre implantes osteointegrados, técnica que se ha incorporado a la práctica estomatológica en Cuba como alternativa al tratamiento convencional en los pacientes desdentados totales. Se siguió un protocolo que comprendió una fase quirúrgica, procedimiento con o sin realización de colgajo y carga precoz o inmediata. Se presenta un paciente masculino de 56 años de edad, que acudió a la consulta multidisciplinaria, preocupado, porque se le habían elaborado tres prótesis en los últimos dos años y ninguna reunía los requisitos de retención que él necesitaba para sentirse seguro y cómodo con las mismas. El resultado final fue la satisfacción total del paciente, con el mejoramiento de la calidad estética y funcional.This is the case of a total maxilla edentulous patient seen in consultation of the "Pedro Ortíz" Clinic Implant of Habana del Este municipality in 2009 and con rehabilitation by prosthesis over osteointegration implants added to stomatology practice in Cuba as an alternative to conventional treatment in patients totally edentulous. We follow a protocol including a surgery or surgical phase, technique without or with flap creation and early or immediate load. This is a male patient aged 56 came to our multidisciplinary consultation worried because he had three prostheses in last two years and any fulfilled the requirements of retention to feel safe and comfortable with prostheses. The final result was the total satisfaction of rehabilitated patient improving its aesthetic and functional quality.

  19. Conjunctival mucinous adenocarcinoma in an ostrich (Struthio camelus)

    DEFF Research Database (Denmark)

    Perrin, Kathryn L; Bertelsen, Mads F; Bartholin, Henrik

    2017-01-01

    . Gross examination revealed a botryoid mass attached to the inferior palpebral conjunctiva and extending onto the palpebral aspect of the nictitating membrane. Euthanasia was selected, and the histological diagnosis of the second mass was a mixed mucinous adenocarcinoma; however, no acid-fast bacteria...

  20. Treatment on Lower Blepharoplasty in Middle-aged and Elderly Patients with Combined Conjunctivae-road Operation and Fractional Laser Rhytidectomy%内路法手术联合点阵激光治疗中老年眼袋

    Institute of Scientific and Technical Information of China (English)

    唐建兵; 程飚; 李勤; 蔡金辉; 苑凯华; 吴燕虹; 柳大烈

    2011-01-01

    目的 探讨内路法手术联合点阵激光治疗中老年眼袋的临床疗效.方法 对52例不愿意行外切口眼袋整复术的中老年患者,先采用内路法手术祛除眶隔多余脂肪,术后2周开始采用点阵激光收紧松弛的下睑和外眦皮肤以减轻皱纹,视情况共治疗1~3次,治疗后1个月进行疗效评估.结果 全部病例术后下睑基本平整,皮肤皱纹明显减轻.4例在点阵激光治疗后出现暂时性色素沉着,2-3个月后自行消退.未出现其他并发症.结论 内路法手术联合点阵激光治疗中老年眼袋效果良好,无切口瘢痕,并发症少,手术恢复快,值得推广.%Objective To investigate the clinicsl effects of combind trans-conjunctivae road operation and fractional laser rhytidectomy on lower blepharoplasty in middle-aged and elderly patients.Methods Conjunctivae-road blepharoplasty was carried out in 52 patients who were unwill to endure trans-skin road operation.The excess fat was removed within orbital septum first.Fractional laser was used to tighten the relaxed skin and reduce wrinkles on the lower eyelid and the outer canthns 2 weeks after operation.The patients were treated 1 to 3 times according to the condition of patients.The treatment effect was assessed 1 month after treatment.Results After the conjunctivae-road operation combined with fractional laser rhytidectomy, the lower eyelid skin became flat and the wrinkles were reduced in all patients.Temporary pigmentation occurred in 4 patients after fractional laser treatment, which regressed spontaneously after 2 to 3 months, no other complications occurred.Conclusions The clinical effects of trans-conjunctivae operation combined with fractional laser rhytidectomy on lower blepharoplasty in middle-ged and elderly patients are good, with no scar and fewer complications.The patients recover quickly.The combined treatment is worth to recommend.

  1. Paso superior en una ladera

    Directory of Open Access Journals (Sweden)

    Bender, O.

    1965-07-01

    Full Text Available The Redwood highway, through the Californian forest, runs on a viaduct, as it crosses a mountain slope of about 45° inclination. The firm ground is fairly deep, and as an additional constructional difficulty, it was necessary to respect the natural beauty of the countryside. A structure of portal frames were built, forming a number of short spans. These spans were bridged with metal girders, on which a 19 m wide deck was placed. The columns are hollow and have a transversal cross beam, to join each pair. There was difficulty in excavating the foundations for the columns, as it was necessary to dig through the soft top soil, and also prevent this soil from hurting the trunks of the forest trees. Another significant difficulty in the construction of this viaduct was the access to the working site, since there were no suitable platforms from which to operate the appropriate machinery. This made it necessary to do a lot of the work by manual operation. As one of the edges of the deck is very close to the mountain side, a supporting beam was erected on this side. It was made of concrete, on metal piles. The formwork for the deck structure was placed on the concrete stems of the supporting piles.La autopista denominada Redwood (California salva, con un paso superior, la ladera de un bosque cuya pendiente es del 1/1. El terreno firme se halla a bastante profundidad, añadiéndose, a los naturales problemas de la construcción, el imperativo de respetar la belleza agreste del paraje. La solución adoptada consiste en una estructura porticada, con varios tramos de pequeñas luces, salvados con vigas metálicas, sobre los que se coloca la losa del tablero, de 19 m de anchura total. Los soportes están constituidos por pórticos de dos montantes huecos (con bases de hormigón en masa por debajo del suelo, hasta el firme coronados por un cabezal. La perforación de pozos para el hormigonado de los montantes presentaba la dificultad de atravesar el terreno

  2. Malignant lymphoma of the conjunctiva

    DEFF Research Database (Denmark)

    Kirkegaard, Marina M; Coupland, Sarah E; Prause, Jan U;

    2015-01-01

    Conjunctival lymphomas constitute 25% of all ocular adnexal lymphomas. The majority are B-cell non-Hodgkin lymphomas (NHLs) (98%), whereas conjunctival T-cell NHLs are rare (2%). The most frequent subtype of conjunctival B-cell lymphoma is extranodal marginal zone lymphoma (EMZL; 81%), followed b...

  3. Pseudodisplacements of superior vena cava catheter in the persistent left superior vena cava

    Energy Technology Data Exchange (ETDEWEB)

    Jantsch, H.; Draxler, V.; Muhar, U.; Schlemmer, M.; Waneck, R.

    1983-01-01

    Pseudodisplacement of a left sided superior vena cava catheter in a persistent superior vena cava may be expected in adults in 0,37% and in a group of children with congenital heart disease in 2,5%. Embryology, anatomy and clinical implications is discussed on the basis of our own cases. The vena cava superior sinistra persitents is depending on a sufficient calibre a suitable vessel for a superior cava catheter.

  4. Superiority in value and the repugnant conclusion

    DEFF Research Database (Denmark)

    Jensen, Karsten Klint

    2007-01-01

    James Griffin has considered a weak form of superiority in value a possible remedy to the Repugnant Conclusion. In this paper, I demonstrate that, in a context where value is additive, this weaker form collapses into a stronger form of superiority. And in a context where value is non-additive, weak...... superiority does not amount to a radical value difference at all. I then spell out the consequences of these results for different interpretations of Griffin's suggestion regarding population ethics. None of them comes out very successful, but perhaps they nevertheless retain some interest....

  5. Millian superiorities and the repugnant conclusion

    DEFF Research Database (Denmark)

    Jensen, Karsten Klint

    2008-01-01

    James Griffin has considered a form of superiority in value that is weaker than lexical priority as a possible remedy to the Repugnant Conclusion. In this article, I demonstrate that, in a context where value is additive, this weaker form collapses into the stronger form of superiority. And in a ......James Griffin has considered a form of superiority in value that is weaker than lexical priority as a possible remedy to the Repugnant Conclusion. In this article, I demonstrate that, in a context where value is additive, this weaker form collapses into the stronger form of superiority...... of these results for different interpretations of Griffin's suggestion regarding population ethics. None of them comes out very successful, but perhaps they nevertheless retain some interest....

  6. Measuring Financial Gains from Genetically Superior Trees

    Science.gov (United States)

    George Dutrow; Clark Row

    1976-01-01

    Planting genetically superior loblolly pines will probably yield high profits.Forest economists have made computer simulations that predict financial gains expected from a tree improvement program under actual field conditions.

  7. Superior mesenteric artery syndrome causing growth retardation

    Directory of Open Access Journals (Sweden)

    Halil İbrahim Taşcı

    2013-03-01

    Full Text Available Superior mesenteric artery syndrome is a rare and lifethreateningclinical condition caused by the compressionof the third portion of the duodenum between the aortaand the superior mesenteric artery’s proximal part. Thiscompression may lead to chronic intermittent, acute totalor partial obstruction. Sudden weight-loss and the relateddecrease in the fat tissue are considered to be the etiologicalreason of acute stenosis. Weight-loss accompaniedby nausea, vomiting, anorexia, epigastric pain, andbloating are the leading complaints. Barium radiographs,computerized tomography, conventional angiography,tomographic and magnetic resonance angiography areused in the diagnosis. There are medical and surgical approachesto treatment. We hereby present the case ofa patient with superior mesenteric artery syndrome withdelayed diagnosis.Key words: superior mesenteric artery syndrome, nausea-vomiting, anorexia

  8. Leiomyosarcoma of the superior vena cava.

    Science.gov (United States)

    de Chaumont, Arthus; Pierret, Charles; de Kerangal, Xavier; Le Moulec, Sylvestre; Laborde, François

    2014-08-01

    Leiomyosarcoma of the superior vena cava is a very rare tumor and only a few cases have been reported, with various techniques of vascular reconstruction. We describe a new case of leiomyosarcoma of the superior vena cava in a 61-year-old woman with extension to the brachiocephalic arterial trunk. Resection and vascular reconstruction were performed using, respectively, polytetrafluoroethylene and polyethylene terephtalate vascular grafts.

  9. Superior mesenteric artery compression syndrome - case report

    OpenAIRE

    Paulo Rocha França Neto; Rodrigo de Almeida Paiva; Antônio Lacerda Filho; Fábio Lopes de Queiroz; Teon Noronha

    2011-01-01

    Superior mesenteric artery syndrome is an entity generally caused by the loss of the intervening mesenteric fat pad, resulting in compression of the third portion of the duodenum by the superior mesenteric artery. This article reports the case of a patient with irremovable metastatic adenocarcinoma in the sigmoid colon, that evolved with intense vomiting. Intestinal transit was carried out, which showed important gastric dilation extended until the third portion of the duodenum, compatible wi...

  10. Impression cytology: a novel sampling technique for conjunctival cytology of the feline eye.

    Science.gov (United States)

    Eördögh, Réka; Schwendenwein, Ilse; Tichy, Alexander; Nell, Barbara

    2015-07-01

    Impression cytology is a noninvasive investigation of the ocular surface. It uses the adhesive features of different filter papers to collect a monolayer of epithelial cells from the cornea and/or conjunctiva. Samples obtained by impression cytology exhibit all characteristics of an ideal cytology specimen. The aim of this study was to test the feasibility of impression cytology and determine the most appropriate filter paper to achieve maximum diagnostic value of the feline eye. Ten healthy cats. The study was conducted in two phases. In the first phase, eight different filter papers (FPs) with various pore sizes were tested: 3.0-, 1.2-, 0.8-, 0.45-, 0.22-, 0.05- and 0.025-μm cellulose acetate papers and a 0.4-μm Biopore membrane (BM). Samples were obtained from the superior bulbar and from the inferior palpebral conjunctiva. In the second phase, three different sampling methods - with and without topical anesthesia, and with topical anesthesia and drying of the conjunctiva - were compared employing the BM encased in the intended BM device (BMD). Samples were evaluated for cellularity and quality of cells. In the first phase, samples obtained from the superior bulbar conjunctiva with the BM had the most sufficient cellularity and quality. In the second phase, BMD with topical anesthesia and additional drying of the conjunctiva was the most ideal method. The BMD may prove to be a suitable diagnostic tool for clinicians. Sampling is quick, processing is simple, and a large area of intact cells can be harvested. © 2014 American College of Veterinary Ophthalmologists.

  11. Superior oblique surgery: when and how?

    Directory of Open Access Journals (Sweden)

    Taylan Şekeroğlu H

    2013-08-01

    Full Text Available Hande Taylan Şekeroğlu,1 Ali Sefik Sanac,1 Umut Arslan,2 Emin Cumhur Sener11Department of Ophthalmology, 2Department of Biostatistics, Hacettepe University Faculty of Medicine, Ankara, TurkeyBackground: The purpose of this paper is to review different types of superior oblique muscle surgeries, to describe the main areas in clinical practice where superior oblique surgery is required or preferred, and to discuss the preferred types of superior oblique surgery with respect to their clinical outcomes.Methods: A consecutive nonrandomized retrospective series of patients who had undergone superior oblique muscle surgery as a single procedure were enrolled in the study. The diagnosis, clinical features, preoperative and postoperative vertical deviations in primary position, type of surgery, complications, and clinical outcomes were reviewed. The primary outcome measures were the type of strabismus and the type of superior oblique muscle surgery. The secondary outcome measure was the results of the surgeries.Results: The review identified 40 (20 male, 20 female patients with a median age of 6 (2–45 years. Nineteen patients (47.5% had Brown syndrome, eleven (27.5% had fourth nerve palsy, and ten (25.0% had horizontal deviations with A pattern. The most commonly performed surgery was superior oblique tenotomy in 29 (72.5% patients followed by superior oblique tuck in eleven (27.5% patients. The amount of vertical deviation in the fourth nerve palsy and Brown syndrome groups (P = 0.01 for both and the amount of A pattern in the A pattern group were significantly reduced postoperatively (P = 0.02.Conclusion: Surgery for the superior oblique muscle requires experience and appropriate preoperative evaluation in view of its challenging nature. The main indications are Brown syndrome, fourth nerve palsy, and A pattern deviations. Superior oblique surgery may be effective in terms of pattern collapse and correction of vertical deviations in primary

  12. Whisker-related afferents in superior colliculus.

    Science.gov (United States)

    Castro-Alamancos, Manuel A; Favero, Morgana

    2016-05-01

    Rodents use their whiskers to explore the environment, and the superior colliculus is part of the neural circuits that process this sensorimotor information. Cells in the intermediate layers of the superior colliculus integrate trigeminotectal afferents from trigeminal complex and corticotectal afferents from barrel cortex. Using histological methods in mice, we found that trigeminotectal and corticotectal synapses overlap somewhat as they innervate the lower and upper portions of the intermediate granular layer, respectively. Using electrophysiological recordings and optogenetics in anesthetized mice in vivo, we showed that, similar to rats, whisker deflections produce two successive responses that are driven by trigeminotectal and corticotectal afferents. We then employed in vivo and slice experiments to characterize the response properties of these afferents. In vivo, corticotectal responses triggered by electrical stimulation of the barrel cortex evoke activity in the superior colliculus that increases with stimulus intensity and depresses with increasing frequency. In slices from adult mice, optogenetic activation of channelrhodopsin-expressing trigeminotectal and corticotectal fibers revealed that cells in the intermediate layers receive more efficacious trigeminotectal, than corticotectal, synaptic inputs. Moreover, the efficacy of trigeminotectal inputs depresses more strongly with increasing frequency than that of corticotectal inputs. The intermediate layers of superior colliculus appear to be tuned to process strong but infrequent trigeminal inputs and weak but more persistent cortical inputs, which explains features of sensory responsiveness, such as the robust rapid sensory adaptation of whisker responses in the superior colliculus. Copyright © 2016 the American Physiological Society.

  13. Superior-subordinate relations as organizational processes

    DEFF Research Database (Denmark)

    Asmuss, Birte; Aggerholm, Helle Kryger; Oshima, Sae

    Since the emergence of the practice turn in social sciences (Golsorkhi et al. 2010), studies have shown a number of institutionally relevant aspects as achievements across time and by means of various resources (human and non-human) (Taylor & van Every 2000, Cooren et al. 2006). Such a process view...... on organizational practices relates closely to an increased focus on communication as being constitutive of the organization in general and the superior-subordinate relationship in specific. The current study aims to contribute to this line of research by investigating micro-practices involved in establishing...... superior-subordinate relations in a specific institutionalized setting: performance appraisal interviews (PAIs). While one main task of PAIs is to manage and integrate organizational and employee performance (Fletcher, 2001:473), PAIs are also organizational practices where superior-subordinate relations...

  14. Lake Superior Aquatic Invasive Species Complete Prevention Plan

    Science.gov (United States)

    The Lake Superior Aquatic Invasive Species Complete Prevention Plan is an expression of the best professional judgment of the members of the Lake Superior Task Force as to what is necessary to protect Lake Superior from new aquatic invasive species.

  15. Endovascular treatment of superior vena cava syndrome

    DEFF Research Database (Denmark)

    Duvnjak, Stevo; Andersen, Poul Erik

    2011-01-01

    Abstract AIM: The aim of this study was to report our experience with palliative stent treatment of superior vena cava syndrome. METHODS: Between January 2008 and December 2009, 30 patients (mean age 60.7 years) were treated with stents because of stenosed superior vena cava. All patients presented...... there was an immediate clinical improvement with considerable reduction in the edema of upper extremities and head. There was, however, continous dyspnea in five patients (17%) and two patients (7%) had persistent visible collateral venous circulations on the upper chest. There were no stent associated complications...

  16. Magnetic resonance imaging evaluation of meniscoid superior labrum: normal variant or superior labral tear*

    Science.gov (United States)

    Simão, Marcelo Novelino; Vinson, Emily N.; Spritzer, Charles E.

    2016-01-01

    Objective The objective of this study was to determine the incidence of a "meniscoid" superior labrum. Materials and Methods This was a retrospective analysis of 582 magnetic resonance imaging examinations of shoulders. Of those 582 examinations, 110 were excluded, for a variety of reasons, and the final analysis therefore included 472 cases. Consensus readings were performed by three musculoskeletal radiologists using specific criteria to diagnose meniscoid labra. Results A meniscoid superior labrum was identified in 48 (10.2%) of the 472 cases evaluated. Arthroscopic proof was available in 21 cases (43.8%). In 10 (47.6%) of those 21 cases, the operative report did not include the mention a superior labral tear, thus suggesting the presence of a meniscoid labrum. In only one of those cases were there specific comments about a mobile superior labrum (i.e., meniscoid labrum). In the remaining 11 (52.4%), surgical correlation demonstrated superior labral tears. Conclusion A meniscoid superior labrum is not an infrequent finding. Depending upon assumptions and the requirement of surgical proof, the prevalence of a meniscoid superior labrum in this study was between 2.1% (surgically proven) and 4.8% (projected). However, superior labral tears are just as common and are often confused with meniscoid labra. PMID:27777474

  17. Superior-subordinate relations as organizational processes

    DEFF Research Database (Denmark)

    Asmuss, Birte; Aggerholm, Helle Kryger; Oshima, Sae

    Since the emergence of the practice turn in social sciences (Golsorkhi et al. 2010), studies have shown a number of institutionally relevant aspects as achievements across time and by means of various resources (human and non-human) (Taylor & van Every 2000, Cooren et al. 2006). Such a process view...... superior-subordinate relations in a specific institutionalized setting: performance appraisal interviews (PAIs). While one main task of PAIs is to manage and integrate organizational and employee performance (Fletcher, 2001:473), PAIs are also organizational practices where superior-subordinate relations...... are shaped, (re)confirmed and re-evaluated. This paper pursues the better understanding of the latter aspect by looking at one substantial and recurrent activity in PAIs: the evaluation of employee performance. One resource for doing the evaluation work is making assessments (e.g. Goodwin & Goodwin, 1987...

  18. Exploring the word superiority effect using TVA

    DEFF Research Database (Denmark)

    Starrfelt, Randi

    Words are made of letters, and yet sometimes it is easier to identify a word than a single letter. This word superiority effect (WSE) has been observed when written stimuli are presented very briefly or degraded by visual noise. It is unclear, however, if this is due to a lower threshold...... for perception of words, or a higher speed of processing for words than letters. We have investigated the WSE using methods based on a Theory of Visual Attention. In an experiment using single stimuli (words or letters) presented centrally, we show that the classical WSE is specifically reflected in perceptual...... processing speed: words are simply processed faster than single letters. It is also clear from this experiment, that the word superiority effect can be observed at a large range of exposure durations, from the perceptual threshold to ceiling performance. Intriguingly, when multiple stimuli are presented...

  19. Microbiota fúngica da conjuntiva, da cana-de-açúcar e de anemófilos da região canavieira de Monte Belo - Minas Gerais Fungic microbiota of normal conjunctiva, sugar-cane and anemophilous fungi of the region of Monte Belo - Minas Gerais

    Directory of Open Access Journals (Sweden)

    Joyce Treinta Dalfré

    2007-06-01

    condições ambientais, o padrão socioeconômico e as más condições higiênicas gerais e pessoais, aliadas à falta de informação sobre normas de profilaxia, influenciaram nos resultados. A incidência foi muito superior no sexo masculino (84,38% em contraposição ao feminino (15,62%. Os fungos anemófilos e os isolados do colmo e folhas foram semelhantes aos já descritos na literatura. Os isolados de fungos filamentosos foram superiores aos de leveduras, havendo uma certa correlação entre estes e os isolados da conjuntiva.AIM: To evaluate the incidence of fungi in the ocular conjunctiva of sugar-cane cutting workers as well in a sugar-cane plantation environment. PLACE: Monte Belo - MG, Eye Clinic, Laboratory of Physiology and Biology of Microorganisms of Unifenas, Alfenas - MG. METHODS: Swabs were made from the ocular conjunctiva of one hundred workers of both sexes and material was collected from leaves, stalk, and the environmental air from the sugar-cane plantation. These were inoculated in specific mold media. After incubation at 25°C for a period of fifteen days, the plates were analyzed and colony forming units (ufc were identified using conventional mycological techniques. RESULTS: Of one hundred workers involved in this research, 64 presented one or more genera of fungi, 54 (84.38% being identified in males and 10 (15.62% identified in females. The separation of the workers by age range showed that the prevalence of observed fungi by age was not uniform. The highest incidences were found in advanced age ranges, the increase of positivity by age being considered statistically significant (p<0.05. The lowest prevalence (50% was found in the 11-20-year-old interval, which presents the lowest number of examined persons. The highest positivity was verified in the 61-79 year interval. In 60 workers (93.75% only one genus was isolated; in 3 (4.69% two genera, and in only one worker (1.56% three genera were isolated. The most prevalent isolated fungi were

  20. Resolution of superior oblique myokymia with memantine.

    Science.gov (United States)

    Jain, Saurabh; Farooq, Shegufta J; Gottlob, Irene

    2008-02-01

    We describe a novel treatment of superior oblique myokymia. A 40-year-old woman was treated with gabapentin for this disorder with partial success and reported significant side effects including loss of libido and weight gain. After a drug holiday, memantine therapy was initiated resulting in a substantial improvement in her symptoms with far fewer side effects and stability on long-term maintenance therapy.

  1. Locked Superior Dislocation of the Acromioclavicular Joint

    Directory of Open Access Journals (Sweden)

    Salma Eltoum Elamin

    2013-01-01

    Full Text Available Acromioclavicular (AC joint injuries account for approximately 3–5% of shoulder girdle injuries (Rockwood et al., 1998. Depending on severity of injury and direction of displacement these are classified using Rockwood classification system for AC joint dislocation. We present an unusual case presenting with locked superior dislocation of the AC joint highlighting the presentation and subsequent successful surgical management of such case. To our knowledge this has not been reported previously in literature.

  2. Reperfusion hemorrhage following superior mesenteric artery stenting.

    LENUS (Irish Health Repository)

    Moore, Michael

    2012-02-03

    Percutaneous transluminal angioplasty and stent placement is now an established treatment option for chronic mesenteric ischemia and is associated with low mortality and morbidity rates. We present a case of reperfusion hemorrhage complicating endovascular repair of superior mesenteric artery stenosis. Although a recognized complication following repair of carotid stenosis, hemorrhage has not previously been reported following mesenteric endovascular reperfusion. We describe both spontaneous cessation of bleeding and treatment with coil embolization.

  3. [Mitral surgery by superior biatrial septotomy].

    Science.gov (United States)

    Saade, A; Delepine, G; Lemaitre, C; Baehrel, B

    1995-01-01

    The superior biatrial septotomy approach consists of two semicircular right atrial and septal incisions joined at the superior end of the interatrial septum and extended across the dome of the left atrium, allowing exposure of the mitral valve by reflecting the ventricular side using stay sutures. From 1991 to 1993, 81 patients underwent mitral valve surgery by this technic. Mitral valve operation was combined with other cardiac procedures in 30 patients (37%) and was performed as a second operation in 21 patients (25.9%). Duration of cardiopulmonary bypass and aortic occlusion was not significantly different from that of patients operated via a conventional left atrial approach. The five hospital deaths (6.2%) were not related to this operative approach. Only 2 patients (3.3%) with preoperative in sinus rythm were discharged in atrial fibrillation after operation. In one patient (1.6%), atrioventricular block appeared at late follow-up. There were no cases of bleeding, atrioventricular nodal dysfunction or intra-atrial shunting related to the approach. This approach provides excellent exposure of the mitral valve even in unfavorable situations such as a small left atrium, dense adhesions from previous procedures or a previously implanted aortic prosthesis, without damage to various cardiac structures due to excessive traction. No retractor or vena cava repair are required. These data support a wide application of the superior biatrial septotomy approach in mitral valve surgery.

  4. Superior mesenteric artery compression syndrome - case report

    Directory of Open Access Journals (Sweden)

    Paulo Rocha França Neto

    2011-12-01

    Full Text Available Superior mesenteric artery syndrome is an entity generally caused by the loss of the intervening mesenteric fat pad, resulting in compression of the third portion of the duodenum by the superior mesenteric artery. This article reports the case of a patient with irremovable metastatic adenocarcinoma in the sigmoid colon, that evolved with intense vomiting. Intestinal transit was carried out, which showed important gastric dilation extended until the third portion of the duodenum, compatible with superior mesenteric artery syndrome. Considering the patient's nutritional condition, the medical team opted for the conservative treatment. Four months after the surgery and conservative measures, the patient did not present vomiting after eating, maintaining previous weight. Superior mesenteric artery syndrome is uncommon and can have unspecific symptoms. Thus, high suspicion is required for the appropriate clinical adjustment. A barium examination is required to make the diagnosis. The treatment can initially require gastric decompression and hydration, besides reversal of weight loss through adequate nutrition. Surgery should be adopted only in case of clinical treatment failure.A síndrome da artéria mesentérica superior é uma entidade clínica causada geralmente pela perda do tecido adiposo mesentérico, resultando na compressão da terceira porção do duodeno pela artéria mesentérica superior. Esse artigo relata o caso clínico de uma paciente portadora de adenocarcinoma de cólon sigmoide metastático irressecável, que evoluiu com vômitos incoercíveis. Realizou-se, então, trânsito intestinal que evidenciou dilatação gástrica importante, que se prolongava até a terceira porção duodenal, quadro radiológico compatível com pinçamento da artéria mesentérica superior. Diante da condição nutricional da paciente, foi optado por iniciar medidas conservadoras (porções alimentares pequenas e mais frequentes, além de dec

  5. Anatomical features and clinical application of compound flap pedicled with arterial arch of palpebral margin%以睑缘动脉弓为蒂的睑缘复合组织瓣的解剖学及临床应用

    Institute of Scientific and Technical Information of China (English)

    赵天兰; 程新德; 熊绍虎; 谢晓明; 余道江

    2008-01-01

    目的 通过对眼睑血供解剖的详细观测,为应用以睑缘动脉弓为蒂的睑缘复合组织瓣修复眼睑缺损提供解剖学依据,并证明该方法是一种修复睑缘全层缺损的理想方法.方法 对15具尸体30侧眼睑进行解剖学观测,重点研究睑缘动脉弓的血供来源、走行分布、外径及吻合情况.对30例临床病例进行回顾性总结,评价本术式的治疗效果.结果 眼睑由内向外可分为皮肤、皮下组织、肌肉层、睑板层、结膜层5层.眼睑内的大部分血管互相吻合,血液循环丰富.鼻背动脉的分支和泪腺动脉的分支共同组成睑缘动脉弓和周边动脉弓,共同营养睑板前后的组织.临床30例睑缘复合组织瓣全部成活,伤口Ⅰ期愈合,无明显继发畸形,外形满意.结论 以睑缘动脉弓为蒂的睑缘复合组织瓣血供可靠,用于睑缘全层缺损的修复为同类组织修复,是一种理想并且效果满意的修复睑缘缺损的方式.%Objective To explore the anatomical basis for clinical application of the compound flap pedicled with arterial arch of palpebral margin by observing eyelid blood supply and anatomical structure and to prove that it is an ideal method of repairing the eyelid defect for clinical application. Methods 15 adult cadavers (30 eyelids) were dissected. The origin, course, branches, diameters and vessel networks of palpebral margin arterial arch were observed particularly. 30 cases of eyelid marginal defect were reviewed and the therapeutic effect of this method evaluated. Results Eyelid was constituted by 5 layers: skin, subcutaneous tissue, muscle, tarsal plate and conjunctival layers. Most eyelid vessels were mutually anastomosed to form a constant vessel network. Palpebral margin arterial arch and peripheral arterial arch were formed by dorsal nasal artery branches and lacrimal artery branches, both of which nourished the eyelid tissue. All the compound flaps of 30 cases survived completely without

  6. Exploring the word superiority effect using TVA

    DEFF Research Database (Denmark)

    Starrfelt, Randi

    Words are made of letters, and yet sometimes it is easier to identify a word than a single letter. This word superiority effect (WSE) has been observed when written stimuli are presented very briefly or degraded by visual noise. It is unclear, however, if this is due to a lower threshold for perc...... simultaneously we find a different pattern: In a whole report experiment with six stimuli (letters or words), letters are perceived more easily than words, and this is reflected both in perceptual processing speed and short term memory capacity....

  7. de educación media superior

    Directory of Open Access Journals (Sweden)

    Enrique Cerón Ferrer

    2007-01-01

    Full Text Available El trabajo presenta los resultados obtenidos en relación al conocimiento y manejo que sobre matemáticas tienen los estudiantes de educación media superior, de los Centros de Estudios Tecnológicos y de Servicios del Distrito Federal, de diferentes carreras que se imparten en estos centros escolares, durante el año 2005. El instrumento de análisis es un cuestionario que contestaron los alumnos, la metodología utilizada es de tipo longitudinal y comparativa.

  8. Pancreaticoduodenectomy with early superior mesenteric artery dissection

    Institute of Scientific and Technical Information of China (English)

    Yu-Fei Xu; Zuo-Jin Liu; Jian-Ping Gong

    2010-01-01

    BACKGROUND: Pancreatic adenocarcinoma remains the fourth leading cause of cancer-related death and is one of the most aggressive human tumors. At present, surgical resection is the only potentially curative treatment. Early neck division is inadequate when invasion of the superior mesenteric artery (SMA) is suspected or in cases of replaced or accessory right hepatic artery. Malignant periampullary tumors often invade retroperitoneal peripancreatic tissues and a positive resection margin is associated with a poor long-term survival. DATA SOURCES: English-language medical databases, PubMed, ELSEVIER and SPRINGERLINK, were searched for articles on"posterior approach pancreaticoduodenectomy","superior mesenteric artery ifrst approach", "retroperitoneal tissue","hanging maneuver", and related topics. RESULTS:The modiifcation allowed the surgeon to early identify the nonresectability of a replaced right hepatic artery if present, enabling complete dissection of the right side of the SMA and portal vein as well as complete excision of the retroportal pancreatic lamina. CONCLUSION: Pancreaticoduodenectomy with early retro-pancreatic dissection is a useful and safe technical variant, which is indicated for the improvement of the safety and curative effect of the procedure.

  9. Radiation treatment of superior sulcus lung carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Millar, J.; Ball, D.; Worotniuk, V.; Smith, J.; Crennan, E.; Bishop, M. [Peter MacCallum Cancer Inst., East Melbourne, VIC (Australia)

    1996-02-01

    The survival of patients with superior sulcus lung carcinoma and the effects of treatment were reviewed. From a prospective database of 4123 consecutive new patients with lung carcinoma, 131 (3.2%) cases of superior sulcus lung carcinoma were identified. Seventy-four patients were planned to receive radiation with palliative intent, 53 radical radiotherapy and one was observed only. The remaining three patients, with small-cell carcinoma, were treated with chemotherapy with or without radiotherapy. Of the 53 radically treated patients, nine were treated with pre-operative radiation prior to intended radical resection. Analysis was carried out on the effect on survival of performance status, nodal involvement, weight loss, vertebral body or rib involvement, treatment intent and radical combined modality treatment compared with radical radiation alone. The estimated median survival for the whole group was 7.6 months; for those treated radically it was 18.3 months, while for the palliatively treated patients it was 3.7 months. Radically treated patients with no initial nodal involvement had an estimated median survival of 22 months, while radically treated patients with nodal involvement had an estimated median survival of 8.4 months (P = 0.003). There were no statistically significant differences in survival between radically treated patients grouped according to initial weight loss, performance status, or vertebral body and rib involvement. Patients treated with pre-operative radiation did not survive significantly longer than patients treated with radiation alone, although the numbers are small. 33 refs., 2 tabs., 4 figs.

  10. Studies on zooplankton of Lago Paione Superiore

    Directory of Open Access Journals (Sweden)

    Patrizia COMOLI

    1999-08-01

    Full Text Available We report here the results of a three year study on the zooplankton of Lago Paione Superiore, an acid sensitive lake above the tree line in the Italian Alps. The research was carried out within MOLAR, an EC-founded Project on “Measuring and Modeling the dynamic response of remote mountain lakes ecosystems to environmental change”. This study comes after a series of investigations on the effects of acidification, in which we documented the changes occurred with decreasing water pHs, by comparing the recent situation with that in the literature of the 40s, and reconstructed the beginning of anthropogenic disturbance through an analysis of the past cladocera assemblages archived in the lake sediments. A characteristic pattern in seasonal periodicity is a transition from a community dominated by small zooplankton (August to a community where the large particle-feeder Daphnia longispina dominates. This is a typical pattern observed in fishless, copepod-cladocera lakes. Regardless from which food is able to exploit, Daphnia population of Lago Paione Superiore is composed by well-fed organisms, visually rich in lipids, able to produce more than one generation/ year of parthenogenetic females at density levels which are rather high in an oligotrophic high mountain lake.

  11. Cochlear implant outcomes in patients with superior canal dehiscence

    NARCIS (Netherlands)

    Puram, Sidharth V.; Roberts, Daniel S.; Niesten, Marlien E F; Dilger, Amanda E.; Lee, Daniel J.

    2015-01-01

    Objective: To determine whether adult cochlear implant (CI) users with superior canal dehiscence syndrome (SCDS) or asymptomatic superior semicircular canal dehiscence (SCD) have different surgical, vestibular, and audiologic outcomes when compared to CI users with normal temporal bone anatomy. Meth

  12. Superior subconjunctival anesthesia versus retrobulbar anesthesia for manual small-incision cataract surgery in a residency training program: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Kongsap P

    2012-11-01

    Full Text Available Pipat KongsapDepartment of Ophthalmology, Prapokklao Hospital, Chanthaburi, Thailand; Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandPurpose: To evaluate the effectiveness of subconjunctival anesthesia as compared to retrobulbar anesthesia for pain control during manual small-incision cataract surgery (MSICS performed by third-year residents.Design: A randomized, controlled trial.Patients and methods: A total of 150 patients undergoing routine cataract surgery were randomly assigned to receive either subconjunctival anesthesia (group 1, n = 75 or retrobulbar anesthesia (group 2, n = 75. Third-year residents performed MSICS using the modified Blumenthal technique. Subconjunctival anesthesia was administered by injecting 2% xylocaine with adrenalin into the superior conjunctiva, and retrobulbar anesthesia by injecting 2 mL of 2% xylocaine with adrenalin into the retrobulbar space. We studied the following variables: intraoperative pain score rated on a 100-point visual analog scale (VAS, operative time, and injection and operative complications.Results: A mean age of 69 vs 70 years, an operative time of 47.1 (SD, 9.9 min vs 47.7 (10.9 min, and a median (interquartile range pain score of 40 (range, 20–70 vs 40 (range, 20–50 were observed in the subconjunctival and the retrobulbar groups, respectively. The injection complication of subconjunctival hemorrhage was significantly higher in the subconjunctival group (25.3% compared to the retrobulbar group (1.3%. The operative complication rate between groups was not different (P > 0.05.Conclusion: Both, superior subconjunctival anesthesia and retrobulbar anesthesia were effective during MSICS when used in a residency training program.Keywords: subconjunctival anesthesia, retrobulbar anesthesia, cataract surgery, small-incision cataract surgery, visual analog scale, pain score

  13. The Superior Transvelar Approach to the Fourth Ventricle and Brainstem

    OpenAIRE

    Ezer, Haim; Banerjee, Anirban Deep; Bollam, Papireddy; Guthikonda, Bharat; Nanda, Anil

    2012-01-01

    Objective The superior transvelar approach is used to access pathologies located in the fourth ventricle and brainstem. The surgical path is below the venous structures, through the superior medullary velum. Following splitting the tentorial edge, near the tentorial apex, the superior medullary velum is split in the cerebello-mesencephalic fissure. Using the supracerebellar infratentorial, transtentorial or parietal interhemispheric routes, the superior medullary velum is approached. Splittin...

  14. 14 CFR 385.7 - Exercise of authority by superiors.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Exercise of authority by superiors. 385.7... Exercise of authority by superiors. Any assignment of authority to a staff member other than the Chief... Department's principle of management responsibility, the superior may choose to exercise the assigned power...

  15. Superiority: China Mobile in the competition

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The market share between China Mobile and China Unicom has stabilized since 2002.It is found that China Mobile has the superiority in the competition, for example, the scissors movement between its revenue and cost indicates that it has a strong profit generating ability and there is enough room for it to reduce the price.The ratio between its price (marginal income) and marginal cost indicates that there is a very distant limit for it to reduce the price.Its demand is obviously flexible with the price, but it does not use the price weapon abundantly.The reason for the stabilization of the market is that China Mobile withdrew from the competition.

  16. MRI manifestations of enlarged superior ophthalmic vein

    Institute of Scientific and Technical Information of China (English)

    WEI Rui-li; MA Xiao-ye; CAI Ji-ping; ZHU Huang

    2002-01-01

    Objective:To assess MRI in the evaluation of enlarged superior ophthalmic vein (SOV). Methods: MRI manifestations and etiology of forty-six patients with enlarged SOV were analyzed. Results: SOV enlargement was noted to occur in carotid-cavernous fistula, ophthalmic Graves'disease, Tolosa-Hunt syndrome, inflammation at the apex of the orbit, orbital pseudotumor and thrombosis of cavernous sinus. The dilated vein appeared as signal void tubular shadows on both T1 and T2 weighted images. The diameter of the enlarged vein was 3.5-6.0 mm. Extraocular muscle enlargement, orbital pathologies, enlarged carotid cavernous sinus etc were also revealed by MRI. Conclusion: The dilated SOV may be well demonstrated by MRI. The etiological diagnosis of enlarged SOV can be made in combination with the associated findings.

  17. Lightning activity during the 1999 Superior derecho

    Science.gov (United States)

    Price, Colin G.; Murphy, Brian P.

    2002-12-01

    On 4 July 1999, a severe convective windstorm, known as a derecho, caused extensive damage to forested regions along the United States/Canada border, west of Lake Superior. There were 665,000 acres of forest destroyed in the Boundary Waters Canoe Area Wilderness (BWCAW) in Minnesota and Quetico Provincial Park in Canada, with approximately 12.5 million trees blown down. This storm resulted in additional severe weather before and after the occurrence of the derecho, with continuous cloud-to-ground (CG) lightning occurring for more than 34 hours during its path across North America. At the time of the derecho the percentage of positive cloud-to-ground (+CG) lightning measured by the Canadian Lightning Detection Network (CLDN) was greater than 70% for more than three hours, with peak values reaching 97% positive CG lightning. Such high ratios of +CG are rare, and may be useful indicators of severe weather.

  18. Analgesia em modelo animal superior para ortopedia

    OpenAIRE

    Oliveira MT, Maria Teresa; Potes, José Alberto; Queiroga, Cristina; Castro, José António; Pereira, Alfredo; Reis, Joana

    2015-01-01

    O teste de novos biomateriais para aplicações clínicas em ortopedia, ou noutras áreas da medicina, em modelos animais vivos e sencientes, em prol do benefício humano, deve ser objecto de planeamento cuidado e ponderado, dado o conflito ético que se coloca. Compete-nos a nós, enquanto investigadores, garantir que as condições de vida, saúde e bem-estar são asseguradas. O uso de ovinos como modelo superior pré-clínico, para investigação em Ortopedia, tem-se evidenciado devido às suas caracterís...

  19. Superior vena cava syndrome in hemodialysis patient

    Directory of Open Access Journals (Sweden)

    Azeb Molhem

    2011-01-01

    Full Text Available Obstruction of blood flow in the superior vena cava (SVC results in symptoms and signs of SVC syndrome. SVC obstruction can be caused either by invasion or external compression of the SVC by contagious pathologic processes involving the right lung, lymph nodes, and other mediastinal structures, or by thrombosis of blood within the SVC. Occasionally, both mechanisms co-exist. We hereby report a case of a 28-year-old male, Saudi patient who was diagnosed with end-stage renal disease and was maintained on regular hemodiaysis via right jugular vein dual lumen catheter for ten months. Three years later, the patient presented with signs and symptoms suggestive of SVC obstruction that was successfully managed with SVC stenting.

  20. [Surgical treatment of superior thoracic outlet syndrome].

    Science.gov (United States)

    Gaibov, A D; Kakhorov, A Z; Sadriev, O N; Yunusov, Kh A

    2015-01-01

    The authors present immediate and long-term results of treatment of 117 patients with superior thoracic outlet syndrome (STOS). There were different reasons for compression of neu- rovascular fascicle in outlet of the thorax. The costaclavicular syndrome was a reason in 48 patients, additional cervical ribs had 36 patients. Skalenus syndrome was noted in 26 cases, rudimentary cervical ribs or hypertrophy of cervical vertebrae C7 had 7 patients. Raynaud's syndrome took place in 19 cases. The required volume of diagnostic procedures and surgical treatment of STOS were determined according to the cause of the syndrome. Differentiated approach to the different forms of STOS was used in relation to dominant symptoms of the disease and reasons for compression of neurovascular fascicle. This allowed getting positive results in majority of patients (90,4%) in long- term period.

  1. ANATOMIC RESEARCH OF SUPERIOR CLUNIAL NERVE TRAUMA

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    In order to find the mechanism of superior clunial nerve (SCN) trauma, we dissected and revealed SCN from 12 corpses (24 sides). Combining 100 sides of SCN trauma, we inspected the course of SCN, the relation between SCN and it's neighbour tissues with the situation of SCN when being subjected to force. We found that the following special anatomic characteristics and mechanical elements such as the course of SCN, it's turning angles, the bony fibrous tube at the iliac crest, the posterior layer of the lumbodorsal fascia and SCN neighbour adipose tissue, are the causes of external force inducing SCN trauma. The anatomic revealment is the guidance of SCN trauma treatment with edged needle.

  2. Superiorization: An optimization heuristic for medical physics

    CERN Document Server

    Herman, G T; Davidi, R; Censor, Y

    2012-01-01

    Purpose: To describe and mathematically validate the superiorization methodology, which is a recently-developed heuristic approach to optimization, and to discuss its applicability to medical physics problem formulations that specify the desired solution (of physically given or otherwise obtained constraints) by an optimization criterion. Methods: The underlying idea is that many iterative algorithms for finding such a solution are perturbation resilient in the sense that, even if certain kinds of changes are made at the end of each iterative step, the algorithm still produces a constraints-compatible solution. This property is exploited by using permitted changes to steer the algorithm to a solution that is not only constraints-compatible, but is also desirable according to a specified optimization criterion. The approach is very general, it is applicable to many iterative procedures and optimization criteria used in medical physics. Results: The main practical contribution is a procedure for automatically p...

  3. Superior calcium homeostasis of extraocular muscles.

    Science.gov (United States)

    Zeiger, Ulrike; Mitchell, Claire H; Khurana, Tejvir S

    2010-11-01

    Extraocular muscles (EOMs) are a unique group of skeletal muscles with unusual physiological properties such as being able to undergo rapid twitch contractions over extended periods and escape damage in the presence of excess intracellular calcium (Ca(2+)) in Duchenne's muscular dystrophy (DMD). Enhanced Ca(2+) buffering has been proposed as a contributory mechanism to explain these properties; however, the mechanisms are not well understood. We investigated mechanisms modulating Ca(2+) levels in EOM and tibialis anterior (TA) limb muscles. Using Fura-2 based ratiometric Ca(2+) imaging of primary myotubes we found that EOM myotubes reduced elevated Ca(2+) ˜2-fold faster than TA myotubes, demonstrating more efficient Ca(2+) buffering. Quantitative PCR (qPCR) and western blotting revealed higher expression of key components of the Ca(2+) regulation system in EOM, such as the cardiac/slow isoforms sarcoplasmic Ca(2+)-ATPase 2 (Serca2) and calsequestrin 2 (Casq2). Interestingly EOM expressed monomeric rather than multimeric forms of phospholamban (Pln), which was phosphorylated at threonine 17 (Thr17) but not at the serine 16 (Ser16) residue. EOM Pln remained monomeric and unphosphorylated at Ser16 despite protein kinase A (PKA) treatment, suggesting differential signalling and modulation cascades involving Pln-mediated Ca(2+) regulation in EOM. Increased expression of Ca(2+)/SR mRNA, proteins, differential post-translational modification of Pln and superior Ca(2+) buffering is consistent with the improved ability of EOM to handle elevated intracellular Ca(2+) levels. These characteristics provide mechanistic insight for the potential role of superior Ca(2+) buffering in the unusual physiology of EOM and their sparing in DMD.

  4. The management of superior sulcus tumors

    Energy Technology Data Exchange (ETDEWEB)

    Komaki, Ritsuko; Cox, J.D.; Putnam, J.B. Jr [Texas Univ., Houston, TX (United States). Anderson Cancer Center] (and others)

    2001-09-01

    Superior sulcus tumors are a rare type of lung cancer arising in the apex of the lung above the sulcus and cause specific symptoms and signs depending on the location and whether the tumor extends into the surrounding structures. Because of the closeness of critical structures to the tumor (e.g., the subclavian artery for anterior lesions, the brachial plexus for lesions in the middle location, and the sympathetic stellate ganglion causing Horner's syndrome [Pancoast's tumor], the vertebral bodies, nerve foramen, and spinal cord for posterior lesions), superior sulcus tumors were often considered marginally respectable or unresectable. Therefore, for many years, preoperative radiation therapy was considered routine treatment for those tumors. However, with the evolution in our understanding of these tumors and modern imaging techniques such as computerized tomography (CT) and magnetic resonant imaging (MRI) and surgical techniques, there is now considerable debate about the roles and timing of surgical resection, radiation therapy, and chemotherapy in the treatment of patients with these tumors. If mediastinoscopy reveals microscopic mediastinal lymph node involvement, the patient can be treated with preoperative concurrent chemoradiotherapy followed by surgery. If there was a gross mediastinal lymph node involvement (N2) on CT, N3 or T4 lesions, the patient can be treated with concurrent chemoradiotherapy with a curative intent; the outcome of such treatment appears to be better than that of sequential chemotherapy followed by radiation therapy. Whenever possible, without compromising the patient's quality of life, surgery should be considered to improve outcome. (author)

  5. STEREO Superior Solar Conjunction Mission Phase

    Science.gov (United States)

    Ossing, Daniel A.; Wilson, Daniel; Balon, Kevin; Hunt, Jack; Dudley, Owen; Chiu, George; Coulter, Timothy; Reese, Angel; Cox, Matthew; Srinivasan, Dipak; hide

    2017-01-01

    With its long duration and high gain antenna (HGA) feed thermal constraint; the NASA Solar-TErestrial RElations Observatory (STEREO) solar conjunction mission phase is quite unique to deep space operations. Originally designed for a two year heliocentric orbit mission to primarily study coronal mass ejection propagation, after 8 years of continuous science data collection, the twin STEREO observatories entered the solar conjunction mission phase, for which they were not designed. Nine months before entering conjunction, an unforeseen thermal constraint threatened to stop daily communications and science data collection for 15months. With a 3.5 month long communication blackout from the superior solar conjunction, without ground commands, each observatory will reset every 3 days, resulting in 35 system resets at an Earth range of 2 AU. As the observatories will be conjoined for the first time in 8 years, a unique opportunity for calibrating the same instruments on identical spacecraft will occur. As each observatory has lost redundancy, and with only a limited fidelity hardware simulator, how can the new observatory configuration be adequately and safely tested on each spacecraft? Without ground commands, how would a 3-axis stabilized spacecraft safely manage the ever accumulating system momentum without using propellant for thrusters? Could science data still be collected for the duration of the solar conjunction mission phase? Would the observatories survive? In its second extended mission, operational resources were limited at best. This paper discusses the solutions to the STEREO superior solar conjunction operational challenges, science data impact, testing, mission operations, results, and lessons learned while implementing.

  6. Lake Superior Coastal Wetland Fish Assemblages and ...

    Science.gov (United States)

    The role of the coastal margin and the watershed context in defining the ecology of even very large lakes is increasingly being recognized and examined. Coastal wetlands are both important contributors to the biodiversity and productivity of large lakes and important mediators of the lake-basin connection. We explored wetland-watershed connections and their relationship to wetland function and condition using data collected from 37 Lake Superior wetlands spanning a substantial geographic and geomorphic gradient. While none of these wetlands are particularly disturbed, there were nevertheless clear relationships between watershed landuse and wetland habitat and biota, and these varied consistently across wetland type categories that reflected the strength of connection to the watershed. For example, water clarity and vegetation structure complexity declined with decreasing percent natural land cover, and these effects were strongest in riverine wetlands (having generally large watersheds and tributary-dominated hydrology) and weakest in lagoon wetlands (having generally small watersheds and lake-dominate hydrology). Fish abundance and species richness both increased with decreasing percent natural land cover while species diversity decreased, and again the effect was strongest in riverine wetlands. Lagoonal wetlands, which lack any substantial tributary, consistently harbored the fewest species of fish and a composition different from the more watershed-lin

  7. Carbon phosphide monolayers with superior carrier mobility

    Science.gov (United States)

    Wang, Gaoxue; Pandey, Ravindra; Karna, Shashi P.

    2016-04-01

    Two dimensional (2D) materials with a finite band gap and high carrier mobility are sought after materials from both fundamental and technological perspectives. In this paper, we present the results based on the particle swarm optimization method and density functional theory which predict three geometrically different phases of the carbon phosphide (CP) monolayer consisting of sp2 hybridized C atoms and sp3 hybridized P atoms in hexagonal networks. Two of the phases, referred to as α-CP and β-CP with puckered or buckled surfaces are semiconducting with highly anisotropic electronic and mechanical properties. More remarkably, they have the lightest electrons and holes among the known 2D semiconductors, yielding superior carrier mobility. The γ-CP has a distorted hexagonal network and exhibits a semi-metallic behavior with Dirac cones. These theoretical findings suggest that the binary CP monolayer is a yet unexplored 2D material holding great promise for applications in high-performance electronics and optoelectronics.Two dimensional (2D) materials with a finite band gap and high carrier mobility are sought after materials from both fundamental and technological perspectives. In this paper, we present the results based on the particle swarm optimization method and density functional theory which predict three geometrically different phases of the carbon phosphide (CP) monolayer consisting of sp2 hybridized C atoms and sp3 hybridized P atoms in hexagonal networks. Two of the phases, referred to as α-CP and β-CP with puckered or buckled surfaces are semiconducting with highly anisotropic electronic and mechanical properties. More remarkably, they have the lightest electrons and holes among the known 2D semiconductors, yielding superior carrier mobility. The γ-CP has a distorted hexagonal network and exhibits a semi-metallic behavior with Dirac cones. These theoretical findings suggest that the binary CP monolayer is a yet unexplored 2D material holding great

  8. Absent right superior caval vein in situs solitus

    DEFF Research Database (Denmark)

    Lytzen, Rebekka; Sundberg, Karin; Vejlstrup, Niels

    2015-01-01

    no postnatal complications. All children were found to have healthy hearts at follow-up. CONCLUSIONS: In all cases, the findings proved to be a benign condition with no clinical manifestations or complications. Although isolated absent right superior caval vein does not seem to affect the outcome, associated......Introduction In up to 0.07% of the general population, the right anterior cardinal vein obliterates and the left remains open, creating an absent right superior caval vein and a persistent left superior caval vein. Absent right superior caval vein is associated with additional congenital heart...... disease in about half the patients. We wished to study the consequences of absent right superior caval vein as an incidental finding on prenatal ultrasonic malformation screening. Material and methods This is a retrospective case series study of all foetuses diagnosed with absent right superior caval vein...

  9. The Business Value of Superior Energy Performance

    Energy Technology Data Exchange (ETDEWEB)

    McKane, Aimee; Scheihing, Paul; Evans, Tracy; Glatt, Sandy; Meffert, William

    2015-08-04

    Industrial facilities participating in the U.S. Department of Energy’s (US DOE) Superior Energy Performance (SEP) program are finding that it provides them with significant business value. This value starts with the implementation of ISO 50001-Energy management system standard, which provides an internationally-relevant framework for integration of energy management into an organization’s business processes. The resulting structure emphasizes effective use of available data and supports continual improvement of energy performance. International relevance is particularly important for companies with a global presence or trading interests, providing them with access to supporting ISO standards and a growing body of certified companies representing the collective knowledge of communities of practice. This paper examines the business value of SEP, a voluntary program that builds on ISO 50001, inviting industry to demonstrate an even greater commitment through third-party verification of energy performance improvement to a specified level of achievement. Information from 28 facilities that have already achieved SEP certification will illustrate key findings concerning both the value and the challenges from SEP/ISO 50001 implementation. These include the facilities’ experience with implementation, internal and external value of third-party verification of energy performance improvement; attractive payback periods and the importance of SEP tools and guidance. US DOE is working to bring the program to scale, including the Enterprise-Wide Accelerator (SEP for multiple facilities in a company), the Ratepayer-Funded Program Accelerator (supporting tools for utilities and program administrators to include SEP in their program offerings), and expansion of the program to other sectors and industry supply chains.

  10. Coronary artery bypass and superior vena cava syndrome.

    OpenAIRE

    Thomas, T V; Masrani, K; Thomas, J.L.

    1999-01-01

    Superior vena cava syndrome is the obstruction of the superior vena cava or its main tributaries by benign or malignant lesions. The syndrome causes edema and engorgement of the vessels on the face, neck, and arms, nonproductive cough, and dyspnea. We discuss the case of a 48-year-old obese diabetic woman who was admitted with unstable angina. She had previously been diagnosed with superior vena cava syndrome. Urgent coronary artery bypass grafting was necessary Although thousands of coronary...

  11. Superiorization of incremental optimization algorithms for statistical tomographic image reconstruction

    Science.gov (United States)

    Helou, E. S.; Zibetti, M. V. W.; Miqueles, E. X.

    2017-04-01

    We propose the superiorization of incremental algorithms for tomographic image reconstruction. The resulting methods follow a better path in its way to finding the optimal solution for the maximum likelihood problem in the sense that they are closer to the Pareto optimal curve than the non-superiorized techniques. A new scaled gradient iteration is proposed and three superiorization schemes are evaluated. Theoretical analysis of the methods as well as computational experiments with both synthetic and real data are provided.

  12. 77 FR 48856 - Safety Zone; Superior Bay, Duluth, MN

    Science.gov (United States)

    2012-08-15

    ... spectators during the Superior Man Triathlon. DATES: This rule is effective from 6 a.m. to 8:30 a.m. on... Triathlon, which are discussed further below. Under 5 U.S.C. 553(d)(3), the Coast Guard finds that good... inaugural Superior Man Triathlon will occur along the Bay of Lake Superior. The 1.2 mile swim leg of...

  13. Superior Mesenteric Artery Syndrome: An Infrequent Complication of Scoliosis Surgery

    Directory of Open Access Journals (Sweden)

    Metin Keskin

    2014-01-01

    Full Text Available Superior mesenteric artery syndrome is a rare condition that causes a proximal small intestinal obstruction due to contraction of the angle between the superior mesenteric artery and the aorta. Scoliosis surgery is one of the 15 reasons for superior mesenteric artery syndrome, which can present with acute or chronic manifestations. Although conservative treatment is usually possible, surgical treatment is required in certain cases that cannot be treated using conservative methods. In this paper, we describe a patient who developed superior mesenteric artery syndrome after scoliosis surgery and was treated with duodenojejunostomy due to failure and complications of conservative treatment.

  14. Superior Vena Cava Thrombosis in a Case of Lung Adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Santanu Ghosh

    2013-01-01

    Full Text Available Superior vena cava syndrome is a common presentation of bronchogenic carcinoma. The mechanism of obstruction is by compression of superior vena cava by the bronchogenic tumor itself or enlarged mediastinal lymph nodes. However obstruction due to intravascular thrombosis is extremely uncommon. Here, we report a rare case of a 65-year-old male smoker who presented with superior vena cava syndrome and bilateral pleural and pericardial effusion with thrombotic occlusion of the superior vena cava in adenocarcinoma of the lung. He was given chemotherapy with carboplatin and gemcitabine with anticoagulant therapy.

  15. [Catheter in the superior vena cava for hemodialysis as a last resort in superior hemithorax].

    Science.gov (United States)

    Restrepo Valencia, C A; Buritica Barragán, C M; Arango, A

    2010-01-01

    We report four patients with chronic kidney disease undergoing haemodialysis therapy, which had exhausted conventional venous access (internal jugular, subclavian) and non-conventional access (axillary, innominate) in the upper hemithorax for haemodialysis. This was primarily due to thrombosis of these veins caused by previous catheterisation. These patients did not qualify for peritoneal dialysis. Using the technique recommended by Archundia et al., 4 indwelling catheters were implanted directly in the superior vena cava in each of the patients with subsequent subcutaneous tunneling. The catheters operated correctly and are currently permeable after being used for an average of 19 months.

  16. Upper eyelid entropion and dry eye in cicatricial trachoma without trichiasis Entrópio de pálpebra superior e olho seco no tracoma cicatricial sem triquíase

    Directory of Open Access Journals (Sweden)

    Abrahão Lucena

    2012-12-01

    Full Text Available PURPOSE: to evaluate the position of the upper eyelid margin and eye surface status in cicatricial trachoma without trichiasis (TS. METHODS: Slit-lamp biomicroscopy was employed to evaluate the location of the upper lid mucocutaneous transition of 156 eyes of 78 patients with trichiasis and of 130 eyes of 65 control subjects. For each eye the position of the upper lid mucocutaneous junction was graded with respect to the line of meibomian gland orifices into 3 categories: a anterior, b at the line, and c posterior to the line. Ocular surface dye staining with lissamine green was performed in all eyes. All participants answered a questionnaire with queries on the presence and intensity of dry eye symptoms. RESULTS: In the eyes with trichiasis the location of the mucocutaneous transition was posterior to the meibomian gland line in 55 (35.3%, at the line in 77 (49.4% and anterior to the line in only 24 (15.4%. In the control group these figures were: 5 (3.8%; 42 (42% and 83 (63.8%. Lissamine staining and dry eye symptoms were also associated with trichiasis. CONCLUSION: Different degrees of upper lid entropion are already present in cicatricial trachoma even in the absence of trichiasis. Trichiasis is associated with lissamine green staining and dry eye symptoms. Conjunctivalization of the upper lid margin may play a role in the development of trachomatous dry eye.OBJETIVOS: Avaliar a posição da margem palpebral superior e a superfície ocular no tracoma cicatricial sem triquíase (TS. MÉTODOS: A localização da transição mucocutânea da pálpebra superior foi avaliada com lâmpada de fenda em 156 olhos de 78 pacientes com triquíase e de 130 olhos de 65 controles. A posição da transição mucocutânea foi classificada em relação à linha das glândulas de Meibômio em três categorias: a anterior, b sobre a linha e c posterior a linha. A superfície ocular de todos os olhos foi avaliada com verde de lissamina. Todos os participantes

  17. Fatal pericardial tamponade after superior vena cava stenting.

    NARCIS (Netherlands)

    Ploegmakers, M.J.M.; Rutten, M.J.C.M.

    2009-01-01

    We discuss a fatal complication of percutaneous superior vena cava (SVC) self-expandable stent placement in a patient with superior vena cava syndrome (SVCS). The SVCS was caused by a malignant mediastinal mass with total occlusion of the SVC. Twenty-four hours after the procedure, the patient died

  18. 33 CFR 117.495 - Superior Oil Canal.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Superior Oil Canal. 117.495 Section 117.495 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Louisiana § 117.495 Superior Oil Canal. The draw of the S82 bridge, mile 6.3, in Cameron...

  19. [Superior vena cava syndrome--surgical solution--case report].

    Science.gov (United States)

    Galie, N; Vasile, R; Savu, C; Petreanu, C; Grigorie, V; Tabacu, E

    2010-01-01

    The patient of 52-year-old smoker was admitted in emergency with headaches, dyspnea, oedema and cyanosis of the cephalic extremity and of the superior members. This signs and symptoms suggest a superior vena cava sindrom. Thoracic CT scan shows the thrombosis of the superior vena cava and a tumor localized in the Bariety's Lodge of about 30/40 mm witch is around the right lateral wall of the traheea.This tumor is also tangent to the superior the superior vena cava. The patient was operated by total median sternotomy. By this approach we performed a complete excision of the mediastinal tumor mass. After that we effected a longitudinal cavotomy, we took out the endoluminal clot and we sutured the superior vena cava. The histological diagnosis of the mediastinal tumor was adenocarcinoma tubular-papillary moderately differentiated. The evolution post operative period was favorable the superior vena cava sindrom was a complet remission. The thoracic CT scan control after 9 months later didn't show a local relapse and blood flow was normally throw the superior vena cava.

  20. Fatal pericardial tamponade after superior vena cava stenting.

    NARCIS (Netherlands)

    Ploegmakers, M.J.M.; Rutten, M.J.C.M.

    2009-01-01

    We discuss a fatal complication of percutaneous superior vena cava (SVC) self-expandable stent placement in a patient with superior vena cava syndrome (SVCS). The SVCS was caused by a malignant mediastinal mass with total occlusion of the SVC. Twenty-four hours after the procedure, the patient died

  1. The superior transvelar approach to the fourth ventricle and brainstem.

    Science.gov (United States)

    Ezer, Haim; Banerjee, Anirban Deep; Bollam, Papireddy; Guthikonda, Bharat; Nanda, Anil

    2012-06-01

    Objective The superior transvelar approach is used to access pathologies located in the fourth ventricle and brainstem. The surgical path is below the venous structures, through the superior medullary velum. Following splitting the tentorial edge, near the tentorial apex, the superior medullary velum is split in the cerebello-mesencephalic fissure. Using the supracerebellar infratentorial, transtentorial or parietal interhemispheric routes, the superior medullary velum is approached. Splitting this velum provides a detailed view of the fourth ventricle and its floor. Materials and Methods A total of 10 formalin-fixed specimens were dissected in a stepwise manner to simulate the superior transvelar approach to the fourth ventricle. The exposure gained the distance from the craniotomy site and the ease of access was assessed for each of the routes. We also present an illustrative case, operated by the senior author (AN). Results The superior transvelar approach provides access to the entire length of the fourth ventricle floor, from the aqueduct to the obex, when using the parietal interhemispheric route. In addition, this approach provides access to the entire width of the floor of the fourth ventricle; however, this requires retracting the superior cerebellar peduncle. Using the supracerebellar infratentorial route gives a limited exposure of the superior part of the fourth ventricle. The occipital interhemispheric route is a compromise between these two. Conclusion The superior transvelar approach to the fourth ventricle provides a route for approaching the fourth ventricle from above. This approach does not require opening the posterior fossa in the traditional way, and provides a reasonable alternative for accessing the superior fourth ventricle.

  2. Epidermoid carcinoma of the conjunctiva. Case report

    Directory of Open Access Journals (Sweden)

    María Adela LLull Tombo

    2011-12-01

    Full Text Available Se presenta el caso de un paciente de 76 años de edad con un carcinoma epidermoide de conjuntiva.  La manifestación clínica principal fue la molestia, el dolor y el ojo rojo. Al examen físico ocular se encontró lesión blanquecina, con vasos sanguíneos en el ángulo interno, por encima del pterigion en ojo derecho. Se diagnosticó como carcinoma epidermoide de la conjuntiva, el cual evolucionó de forma rápida e invasiva. Se intervino quirúrgicamente en tres ocasiones debido a las recurrencias.

  3. Síndrome de Deiscência de Canal Semicircular Superior Superior Canal Dehiscence Syndrome

    Directory of Open Access Journals (Sweden)

    Suzane da Cunha Ferreira

    2006-06-01

    Full Text Available A Síndrome de Deiscência de Canal Semicircular Superior (SDCSS, primeiramente descrita em 1998 por Minor et al., caracteriza-se por vertigem associada à presença de nistagmo, relacionados à exposição a estímulos sonoros intensos ou a modificações de pressão dentro da orelha média ou intracraniana. Disacusia, em sua maioria de padrão condutivo à audiometria tonal, também pode estar presente. Nesta revisão da literatura objetivou-se abordar a SDCSS, com seus principais sinais e sintomas, achados diagnósticos e tratamento, assim como enfatizar a importância de sua inclusão dentre as causas de vertigem, visto tratar-se de acometimento ainda pouco conhecido até mesmo entre especialistas. O diagnóstico correto, além de possibilitar seu tratamento, impede que abordagens diagnósticas e terapêuticas inapropriadas sejam realizadas.The Superior Canal Dehiscence Syndrome (SCDS was first reported by Minor at. Al. (1998, and has been characterized by vertigo and vertical-torsional eye movements related to loud sounds or stimuli that change middle ear or intracranial pressure. Hearing loss, for the most part with conductive patterns on audiometry, may be present in this syndrome. We performed a literature survey in order to to present symptoms, signs, diagnostic and therapeutic approaches to the SCDS, also aiming at stressing the great importance of including this syndrome among the tractable cause of vertigo. We should emphasize that this is a recent issue, still unknown by some specialists. The Correct SCDS diagnosis, besides enabling patient treatment, precludes misdiagnosis and inadequate therapeutic approaches.

  4. Acquired Brown Syndrome Treated With Traction of Superior Oblique Tendon.

    Science.gov (United States)

    Shin, Kwang Hoon; Paik, Hae Jung; Chi, Mijung

    2016-03-01

    Brown syndrome is a rare strabismic disease characterized by a limited elevation in adduction of the eye. The lengthening/weakening of superior oblique muscle is the main way of surgical intervention for this disease. A 7-year-old boy was diagnosed as having acquired Brown syndrome in his right eye after injury in his face. We experienced successful release of this Brown syndrome through mere pulling outward of superior oblique tendon during surgical exploration. We briefly discuss why this manipulation of superior oblique tendon that we performed was successful.

  5. Right superior vena cava draining into the left atrium

    Energy Technology Data Exchange (ETDEWEB)

    Calcagni, Giulio; Sidi, Daniel; Bonnet, Damien [University Rene Descartes-Paris 5, Department of Paediatric Cardiology, Hopital Necker-Enfants Malades, Paris (France); Batisse, Alain [Institut de Puericulture et de Perinatalogie, Paris (France); Vouhe, Pascal [University Rene Descartes-Paris 5, Department of Paediatric Cardiac Surgery, Hopital Necker-Enfants Malades, Paris (France); Ou, Phalla [University Rene Descartes-Paris 5, Department of Paediatric Cardiology, Hopital Necker-Enfants Malades, Paris (France); University Rene Descartes-Paris 5, Department of Pediatric Radiology, Hopital Necker-Enfants Malades, Paris (France)

    2008-08-15

    The right superior vena cava draining into the left atrium is a rare malformation causing cyanosis and clubbing in patients in whom no other signs of congenital heart defect are present. Diagnosis may be difficult as cyanosis may be mild and the anomaly is not always easily detectable by echocardiography. For this reason we report a 13-month-old male in whom we confirmed the clinical and echocardiographic suspicion of anomalous drainage of the right superior vena cava using multidetector CT. This allowed successful surgical reconnection of the right superior vena cava to the right atrium. (orig.)

  6. Noise management to achieve superiority in quantum information systems

    Science.gov (United States)

    Nemoto, Kae; Devitt, Simon; Munro, William J.

    2017-06-01

    Quantum information systems are expected to exhibit superiority compared with their classical counterparts. This superiority arises from the quantum coherences present in these quantum systems, which are obviously absent in classical ones. To exploit such quantum coherences, it is essential to control the phase information in the quantum state. The phase is analogue in nature, rather than binary. This makes quantum information technology fundamentally different from our classical digital information technology. In this paper, we analyse error sources and illustrate how these errors must be managed for the system to achieve the required fidelity and a quantum superiority. This article is part of the themed issue 'Quantum technology for the 21st century'.

  7. 2010 Great Lakes Restoration Initiative Bathymetric Lidar: Lake Superior

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data contained in this file contain hydrographic and topographic data collected by the Fugro LADS Mk II system along the Lake Superior coast of Minnessota,...

  8. 28 CFR 2.60 - Superior program achievement.

    Science.gov (United States)

    2010-07-01

    ... OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2... or a case with both superior program achievement and minor disciplinary infraction(s)). Advancements...

  9. Coronary artery bypass and superior vena cava syndrome.

    Science.gov (United States)

    Thomas, T V; Masrani, K; Thomas, J L

    1999-01-01

    Superior vena cava syndrome is the obstruction of the superior vena cava or its main tributaries by benign or malignant lesions. The syndrome causes edema and engorgement of the vessels on the face, neck, and arms, nonproductive cough, and dyspnea. We discuss the case of a 48-year-old obese diabetic woman who was admitted with unstable angina. She had previously been diagnosed with superior vena cava syndrome. Urgent coronary artery bypass grafting was necessary Although thousands of coronary artery bypasses are performed every year, there are not many reports on patients with superior vena cava syndrome who successfully undergo cardiopulmonary bypass and coronary artery grafting with an internal mammary artery as the conduit. The results of the case and alternative recommended methods are discussed.

  10. Superior memorizers employ different neural networks for encoding and recall.

    Science.gov (United States)

    Mallow, Johannes; Bernarding, Johannes; Luchtmann, Michael; Bethmann, Anja; Brechmann, André

    2015-01-01

    Superior memorizers often employ the method of loci (MoL) to memorize large amounts of information. The MoL, known since ancient times, relies on a complex process where information to be memorized is bound to landmarks along mental routes in a previously memorized environment. However, functional magnetic resonance imaging data on groups of trained superior memorizer are rare. Based on the memorizing strategy reported by superior memorizers, we developed a scheme of the processes successively employed during memorizing and recalling digits and relate these to brain activation that is specific for the encoding and recall period. In the examined superior memorizers several regions, suggested to be involved in mental navigation and digit-to-word processing, were specifically activated during encoding: bilateral early visual cortex, retrosplenial cortex, left parahippocampus, left visual cortex, and left superior parietal cortex. Although the scheme suggests that some steps during encoding and recall seem to be analog, none of the encoding areas were specifically activated during the recall. Instead, we found strong activation in left anterior superior temporal gyrus, which we relate to recalling the sequential order of the digits, and right motor cortex that may be related to reciting the digits.

  11. Superior Memorizers Employ Different Neural Networks for Encoding and Recall

    Directory of Open Access Journals (Sweden)

    Johannes eMallow

    2015-09-01

    Full Text Available Superior memorizers often employ the method of loci (MoL to memorize large amounts of information. The method of loci, known since ancient times, relies on a complex process where information to be memorized is bound to landmarks along mental routes in a previously memorized environment. However, fMRI data on groups of trained superior memorizer are rare. Based on the memorizing strategy reported by superior memorizers we developed a scheme of the processes successively employed during memorizing and recalling digits and relate these to brain activation that is specific for the encoding and recall period. In the examined superior memorizers several regions, suggested to be involved in mental navigation and digit-to-word processing, were specifically activated during encoding: bilateral early visual cortex, retrosplenial cortex, left parahippocampus, left visual cortex, and left superior parietal cortex. Although the scheme suggests that some steps during encoding and recall seem to be analog, none of the encoding areas were specifically activated during the recall. Instead, we found strong activation in left anterior superior temporal gyrus, which we relate to recalling the sequential order of the digits, and right motor cortex that may be related to reciting the digits.

  12. Differential diagnosis of cervical radiculopathy and superior pulmonary sulcus tumor

    Institute of Scientific and Technical Information of China (English)

    GU Rui; KANG Ming-yang; GAO Zhong-li; ZHAO Jian-wu; WANG Jin-cheng

    2012-01-01

    Background The result would be disastrous if the superior pulmonary sulcus tumor (Pancoast tumor) was misdiagnosed as degenerative cervical spine diseases.The aim of this study was to investigate the differential diagnosis methods of cervical radiculopathy and superior pulmonary sulcus tumor.Methods Clinical manifestations,physical,and radiological findings of 10 patients,whose main complaints were radiating shoulder and arm pain and later were diagnosed with superior pulmonary sulcus tumor,were reviewed and compared with those of cervical radiculopathy.Results Superior pulmonary sulcus tumor patients have shorter mean history and fewer complaints of neck pain or limitation of neck movement.Physical examination showed almost normal cervical spine range of motion.Spurling's neck compression test was negative in all patients.Anteroposterior cervical radiographs showed the lack of pulmonary air at the top of the affected lung in all cases and first rib encroachment in one case.The diagnosis of superior pulmonary sulcus tumor can be further confirmed by CT and MRI.Conclusions By the method of combination of history,physical examination,and radiological findings,superior pulmonary sulcus tumor can be efficiently differentiated from cervical radiculopathy.Normal motion range of the cervical spine,negative Spurling's neck compression test,and the lack of pulmonary air at the top of the affected lung in anteroposterior cervical radiographs should be considerad as indications for further chest radiograph examinations.

  13. Veia cava superior esquerda anômala com ausência de veia cava superior direita: achados de imagem Persistent left superior vena cava with absent right superior vena cava: image findings

    Directory of Open Access Journals (Sweden)

    Cyrillo Rodrigues de Araújo Júnior

    2003-10-01

    Full Text Available A persistência da veia cava superior esquerda com ausência da veia cava superior direita é uma anomalia rara, com menos de 150 casos descritos na literatura. A não-obliteração e regressão da veia cardinal anterior esquerda durante o desenvolvimento embriológico promove uma variação sistêmica de retorno venoso ao coração, com persistência da veia cava superior esquerda. Sua incidência varia de 0,3% em pacientes sem alterações cardíacas congênitas concomitantes a 4,3% naqueles com cardiopatias. Na maioria das vezes coexiste a veia cava superior direita, porém se houver regressão e degeneração da veia cardinal anterior direita, implicará a sua ausência e a drenagem venosa para o coração será feita pela veia cava superior esquerda ao átrio direito, através do seio coronariano. Mostramos um caso de um paciente submetido a radiografia de tórax e tomografia computadorizada para avaliação de doença pulmonar obstrutiva crônica, tendo como achado a persistência da veia cava superior esquerda com ausência da direita, sem qualquer cardiopatia associada e com a drenagem cardíaca sendo feita, através do seio coronariano, para o átrio direito.Persistent left superior vena cava with absent right superior vena cava is a rare anomaly, with less than 150 cases reported in the literature. Congenitally persistent left superior vena cava is the most common variant of systemic venous return to the heart, resulting embryologically from failure of the left anterior cardinal vein to become obliterated. Its incidence varies from 0.3% in patients with otherwise normal heart to 4.3% in patients with congenital heart disease. In the majority of the patients, a right superior vena cava is present as well, but rarely the right anterior cardinal vein degenerates resulting in the absence of the normal right superior vena cava. The blood from the right side is carried by the persistent left superior vena cava to the right atrium through the

  14. Superior Canal Dehiscence Syndrome: Lessons from the First 20 Years

    Directory of Open Access Journals (Sweden)

    Bryan K. Ward

    2017-04-01

    Full Text Available Superior semicircular canal dehiscence syndrome was first reported by Lloyd Minor and colleagues in 1998. Patients with a dehiscence in the bone overlying the superior semicircular canal experience symptoms of pressure or sound-induced vertigo, bone conduction hyperacusis, and pulsatile tinnitus. The initial series of patients were diagnosed based on common symptoms, a physical examination finding of eye movements in the plane of the superior semicircular canal when ear canal pressure or loud tones were applied to the ear, and high-resolution computed tomography imaging demonstrating a dehiscence in the bone over the superior semicircular canal. Research productivity directed at understanding better methods for diagnosing and treating this condition has substantially increased over the last two decades. We now have a sound understanding of the pathophysiology of third mobile window syndromes, higher resolution imaging protocols, and several sensitive and specific diagnostic tests. Furthermore, we have a treatment (surgical occlusion of the superior semicircular canal that has demonstrated efficacy. This review will highlight some of the fundamental insights gained in SCDS, propose diagnostic criteria, and discuss future research directions.

  15. La educación superior como eje del desarrollo

    Directory of Open Access Journals (Sweden)

    Benjamín Afanador Vargas

    2003-11-01

    Full Text Available Este documento analiza cómo ha sido la interacción entre la política educativa y las estrategiasde desarrollo en Colombia, a lo largo del siglo XX. Se presenta una revisión del estadoactual de la educación en Colombia, tanto a nivel de educación básica y media, como de laeducación superior. Para ello se toman tres criterios básicos que son la cobertura, la calidady la equidad en el acceso a la educación. Para el caso de la educación superior, se comparala oferta de cupos con la demanda existente, se clasifican los distintos segmentos en que sedivide la educación superior y se hace una breve reseña sobre el recurso humano con que secuenta en la educación superior colombiana. Así mismo, se expone una conceptualización delos retos que enfrenta la educación superior, sobretodo para lograr una cohesión de la sociedad,evitando que algunos de sus integrantes sean excluidos y permitiendo que todos losestamentos de la sociedad puedan compartir los mismos ideales y los consideren asequibles.Finalmente, se presentan unas conclusiones que se derivan del estudio y se proponen algunasrecomendaciones de política .

  16. Design of a fifth generation air superiority fighter

    Science.gov (United States)

    Atique, Md. Saifuddin Ahmed; Barman, Shuvrodeb; Nafi, Asif Shahriar; Bellah, Masum; Salam, Md. Abdus

    2016-07-01

    Air Superiority Fighter is considered to be an effective dogfighter which is stealthy & highly maneuverable to surprise enemy along with improve survivability against the missile fire. This new generation fighter aircraft requires fantastic aerodynamics design, low wing loading (W/S), high thrust to weight ratio (T/W) with super cruise ability. Conceptual design is the first step to design an aircraft. In this paper conceptual design of an Air Superiority Fighter Aircraft is proposed to carry 1 crew member (pilot) that can fly at maximum Mach No of 2.3 covering a range of 1500 km with maximum ceiling of 61,000 ft. Payload capacity of this proposed aircraft is 6000 lb that covers two advanced missiles & one advanced gun. The Air Superiority Fighter Aircraft was designed to undertake all the following missions like: combat air petrol, air to air combat, maritime attack, close air support, suppression, destruction of enemy air defense and reconnaissance.

  17. Temporal Bone Fracture Causing Superior Semicircular Canal Dehiscence

    Directory of Open Access Journals (Sweden)

    Kevin A. Peng

    2014-01-01

    Full Text Available Importance. Superior semicircular canal dehiscence (SCD is a third window lesion of the inner ear causing symptoms of vertigo, autophony, tinnitus, and hearing loss. A “two-hit” hypothesis has traditionally been proposed, whereby thinly developed bone overlying the superior canal is disrupted by a sudden change in intracranial pressure. Although the symptoms of SCD may be precipitated by head injury, no previous reports have described a temporal bone fracture directly causing SCD. Observations. Two patients sustained temporal bone fractures after closed head trauma, and developed unilateral otologic symptoms consistent with SCD. In each instance, computed tomography imaging revealed fractures extending through the bony roof of the superior semicircular canal. Conclusions and Relevance. Temporal bone fractures, which are largely treated nonoperatively, have not previously been reported to cause SCD. As it is a potentially treatable entity, SCD resulting from temporal bone fracture must be recognized as a possibility and diagnosed promptly if present.

  18. Partial anomalous pulmonary venous connection to the superior vena cava.

    Science.gov (United States)

    Aramendi, José I; Rey, Estibaliz; Hamzeh, Gadah; Crespo, Alejandro; Luis, Maite; Voces, Roberto

    2011-04-01

    We describe the surgical technique of reimplantation of the right superior pulmonary vein into the left atrium in 2 patients with partial anomalous pulmonary venous connection to the superior vena cava without atrial septal defect. A right axillary minithoracotomy is done through the fourth intercostal space. The pulmonary vein is detached from its origin in the superior vena cava. This is sutured with 6-0 reabsorbable polydioxanone suture (Ethicon, Somerville, NJ). A lateral clamp is applied to the left atrium, and the pulmonary vein is reimplanted. The patient is extubated in the operating room. Neither cardiopulmonary bypass nor blood transfusion was required. It is simple, safe, and reproducible. Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  19. Isolated abscess in superior rectus muscle in a child

    Directory of Open Access Journals (Sweden)

    Sushank Ashok Bhalerao

    2015-01-01

    Full Text Available Pyomyositis is a primary bacterial infection of striated muscles nearly always caused by Staphylococcus aureus. Development of the intramuscular abscess involving the extra-ocular muscles (EOMs remains an extremely rare process. We herein present a case of isolated EOM pyomyositis involving superior rectus muscle in a 2-year male child who was referred with complaints of swelling in left eye (LE and inability to open LE since last 1-month. Orbital computed tomography (CT scan showed a well-defined, hypo-dense, peripheral rim-enhancing lesion in relation to left superior rectus muscle suggestive of left superior rectus abscess. The abscess was drained through skin approach. We concluded that pyomyositis of EOM should be considered in any patient presenting with acute onset of orbital inflammation and characteristic CT or magnetic resonance imaging features. Management consists of incision and drainage coupled with antibiotic therapy.

  20. Anthropogenic climate change has altered primary productivity in Lake Superior

    Science.gov (United States)

    O'Beirne, M. D.; Werne, J. P.; Hecky, R. E.; Johnson, T. C.; Katsev, S.; Reavie, E. D.

    2017-06-01

    Anthropogenic climate change has the potential to alter many facets of Earth's freshwater resources, especially lacustrine ecosystems. The effects of anthropogenic changes in Lake Superior, which is Earth's largest freshwater lake by area, are not well documented (spatially or temporally) and predicted future states in response to climate change vary. Here we show that Lake Superior experienced a slow, steady increase in production throughout the Holocene using (paleo)productivity proxies in lacustrine sediments to reconstruct past changes in primary production. Furthermore, data from the last century indicate a rapid increase in primary production, which we attribute to increasing surface water temperatures and longer seasonal stratification related to longer ice-free periods in Lake Superior due to anthropogenic climate warming. These observations demonstrate that anthropogenic effects have become a prominent influence on one of Earth's largest, most pristine lacustrine ecosystems.

  1. Noise management to achieve superiority in quantum information systems.

    Science.gov (United States)

    Nemoto, Kae; Devitt, Simon; Munro, William J

    2017-08-06

    Quantum information systems are expected to exhibit superiority compared with their classical counterparts. This superiority arises from the quantum coherences present in these quantum systems, which are obviously absent in classical ones. To exploit such quantum coherences, it is essential to control the phase information in the quantum state. The phase is analogue in nature, rather than binary. This makes quantum information technology fundamentally different from our classical digital information technology. In this paper, we analyse error sources and illustrate how these errors must be managed for the system to achieve the required fidelity and a quantum superiority.This article is part of the themed issue 'Quantum technology for the 21st century'. © 2017 The Author(s).

  2. INFORMATION ASSURANCE - INTELLIGENCE - INFORMATION SUPERIORITY RELATIONSHIP WITHIN NATO OPERATIONS

    Directory of Open Access Journals (Sweden)

    Gheorghe BOARU, Ioan-Mihai ILIEŞ

    2011-01-01

    Full Text Available There is a tight relationship between information assurance, the intelligence cycle and information superiority within NATO operations. The intelligence cycle has a discrete architecture and provides on-time and relevant intelligence products to the joint force commanders and to other authorized users in a specifi c joint area of operations. The intelligence cycle must follow the evolution of the operation. A permanent intelligence estimate will be performed during the military decision making process and operations execution. Information superiority is one of the most powerful intelligence cycle achievements. and decisively infuences the success of NATO joint operations. Information superiority must be preserved and enhanced through information assurance. Information assurance is an information operation that must be planned by the military in charge of operation security or by non-military experts, executed by all personnel during the entire intelligence cycle life time and employed during the planning and execution of NATO joint operations.

  3. Status of the shortjaw cisco (Coregonus zenithicus) in Lake Superior

    Science.gov (United States)

    Hoff, Michael H.; Todd, Thomas N.

    2004-01-01

    The shortjaw cisco (Coregonus zenithicus) was historically found in Lakes Huron, Michigan, and Superior, but has been extirpated in Lakes Huron and Michigan apparently as the result of commercial overharvest. During 1999-2001, we conducted an assessment of shortjaw cisco abundance in five areas, spanning the U.S. waters of Lake Superior, and compared our results with the abundance measured at those areas in 1921-1922. The shortjaw cisco was found at four of the five areas sampled, but abundances were so low that they were not significantly different from zero. In the four areas where shortjaw ciscoes were found, abundance declined significantly by 99% from the 1920s to the present. To increase populations of this once economically and ecologically important species in Lake Superior, an interagency rehabilitation effort is needed. Population monitoring is recommended to assess population trends and to evaluate success of rehabilitation efforts.

  4. The postdiction superiority effect in metacomprehension of text.

    Science.gov (United States)

    Pierce, B H; Smith, S M

    2001-01-01

    Metacomprehension accuracy for texts was greater after, rather than before, answering test questions about the texts-a postdiction superiority effect. Although postdiction superiority was found across successive sets of test questions and across successive texts, there was no improvement in metacomprehension accuracy after participants had taken more tests. Neither prediction nor postdiction gamma correlations with test performance improved with successive tests. Although the results are consistent with retrieval hypotheses, they contradict predictions made by test knowledge hypotheses, which state that increasing knowledge of the nature of the tests should increase metacomprehension accuracy.

  5. Imaging Evaluation of Superior Labral Anteroposterior (SLAP) Tears.

    Science.gov (United States)

    Grubin, Jeremy; Maderazo, Alex; Fitzpatrick, Darren

    2015-10-01

    Superior labral anteroposterior (SLAP) tears are common injuries that are best evaluated with magnetic resonance arthrography (MRA), as it provides the most detailed evaluation of the bicipital labral complex. Given the variety and complexity of SLAP tears, distention of the joint with intra-articular dilute gadolinium contrast properly separates the intra-articular biceps tendon, superior labrum, glenoid cartilage and glenohumeral ligaments to optimize assessment of these structures. This allows for increased diagnostic confidence of the interpreting radiologist and provides a better road map for the surgeon prior to arthroscopy. Indirect MRA and high-field magnetic resonance imaging are sensitive and specific alternative modalities if MRA cannot be performed.

  6. SUPERIOR MESENTERIC ARTERY SYNDROME - AN UNUSUAL CAUSE OF DUODENAL OBSTRUCTION

    OpenAIRE

    Sahu SK, , , , , , ,; Singh PK; Ray J; Uniyal M; Sharma C; Sekhar C; Kapruwan H; Sachan PK

    2012-01-01

    Superior mesenteric artery (SMA) arising from aorta at the level of first lumbar vertebra usually takes an angular downward course from ventral surface of aorta. It is through this vascular angle that the 3rd part of duodenum passes at the level of 4th lumbar vertebra. Fat and lymphatics around SMA maintains the angle at 25° to 60° with a mean of 450 and provide protection against duodenal compression. In Superior Mesenteric Artery Syndrome, the SMA-aorta angle in narrowed down to 7° to 22° w...

  7. Síndrome de veia cava superior Superior vena cava syndrome

    Directory of Open Access Journals (Sweden)

    SAMUEL ZUÍNGLIO DE BIASI CORDEIRO

    2002-09-01

    Full Text Available A obstrução ao fluxo sanguíneo na VCS e suas manifestações clínicas têm hoje como causa principal o câncer de pulmão. A história relata que no século XVIII a sífilis e a tuberculose eram responsáveis por 40% dos casos conhecidos. O conhecimento das alterações hemodinâmicas compreendidas nesta síndrome assim como a apuração das técnicas de diagnóstico de imagem e de citopatologia permitem hoje que o médico possa tratar de seu paciente com mais segurança e conforto do que há 10 anos. A TC contrastada e a RM auxiliam no diagnóstico de localização da obstrução e técnicas mais antigas como a cavografia puderam ser abandonadas. O diagnóstico de obstrução da VCS e o estudo por Doppler realizado à beira do leito em muito contribuem para a realização de procedimentos de desobstrução como a angioplastia transluminal percutânea nos casos de trombose ou estenose do vaso. Também a utilização de próteses como PTFE é de importância fundamental na condução de casos de lesão traumática da VCS durante cirurgias para câncer pulmonar ou mediastinal. No campo da radioterapia, a técnica de fracionamento permite que altas doses de irradiação sejam administradas aos pacientes portadores de neoplasias malignas, com benefícios em 70% dos casos.Lung cancer is now the main cause of blood flow obstruction in the superior vena cava and of its clinical manifestations. History tells that in the 18th Century, syphilis and tuberculosis were responsible for 40% of the known cases. The knowledge of hemodynamic changes seen in this syndrome and the improvement of diagnostic and cytopathologic techniques allow for a safer and more comfortable treatment of the patient than 10 years ago. Contrast CT and MR added to the identification and location of the obstruction, and older techniques such as cavography could be abandoned. SVC obstruction diagnosis and Doppler studies carried out at the bed of the patient contribute to

  8. [Immature palpebral capillary angioma. A case commented on].

    Science.gov (United States)

    Robin, H; Hurbli, T; Morax, S

    1994-01-01

    A three-year-old girl presented a voluminous capillary haemangioma associated with amblyopia. This case failed to respond to steroid treatment. Surgical treatment was necessary. The authors describe evolution, complications and therapeutic management of eyelid angiodysplasia.

  9. Orbito-palpebral reconstruction in two cases of incomplete cryptophthalmos.

    Science.gov (United States)

    Morax, S; Herdan, M L; Hurbli, T

    1992-01-01

    Two cases of congenital symblepharon (variant of cryptophthalmos) are reported. Cryptophthalmos is a very rare congenital defect, with incomplete or complete failure in the development of one or both eyelids with skin recovering the anterior segment. Surgical treatment is described including expansion of the conjunctival fornix with eyeball conservation if possible. At the same time or later, the upper eyelid is reconstructed by inferior eyelid flap. The ophthalmic features of cryptophthalmos and its systemic associations are reviewed.

  10. PTOSE PALPEBRAL – A IMPORTÂNCIA DE VALORIZAR

    Directory of Open Access Journals (Sweden)

    Raquel Oliveira

    2016-07-01

    Comentários: A MG é um distúrbio neuromuscular cujo diagnóstico constitui um desafio nesta faixa etária. Neste caso clínico a manutenção da sintomatologia após a primeira vinda ao SU, motivou uma observação clínica cuidadosa que, apoiada pela deteção de anticorpos anti-AchR, permitiu confirmar o diagnóstico. O diagnóstico precoce é fundamental uma vez que a terapêutica instituída é eficaz.

  11. Biological Motion Task Performance Predicts Superior Temporal Sulcus Activity

    Science.gov (United States)

    Herrington, John D.; Nymberg, Charlotte; Schultz, Robert T.

    2011-01-01

    Numerous studies implicate superior temporal sulcus (STS) in the perception of human movement. More recent theories hold that STS is also involved in the "understanding" of human movement. However, almost no studies to date have associated STS function with observable variability in action understanding. The present study directly associated STS…

  12. O MARKETING NO ENSINO SUPERIOR: COMPARATIVO BRASIL-PORTUGAL

    Directory of Open Access Journals (Sweden)

    Helena Alves

    2010-12-01

    Full Text Available Ao abordar o marketing aplicado ao ensino superior, este estudo tem como objetivos discutir os conceitos teóricos do marketing educacional e aplicálos aos contextos brasileiro e português. Tendo em consideração que o marketing educacional tem a sua maior expressão nos E.U.A., a sua aplicação a diferentes realidades e culturas requer adaptações. Inicialmente, fez-se uma revisão dos conceitos tradicionais de marketing educacional, com ênfase nas vantagens, desvantagens e no marketing-mix aplicado à educação. Posteriormente realizou-se uma caraterização dos contextos atuais do ensino superior no Brasil e em Portugal, e fez-se uma comparação da aplicação do marketing educacional nas realidades brasileira e portuguesa, focando as análises no marketing-mix educacional. Percebeu-se que o ensino superior no Brasil tem caraterísticas muito diversas do ensino superior em Portugal e ambos divergem na aplicação dos conceitos mais tradicionais do marketing à educação. Desta forma, faz-se necessária a construção de abordagens teóricas específicas para a aplicação do marketing educacional a diferentes nações.

  13. Organizational Self-Awareness in the Key to Knowledge Superiority

    Science.gov (United States)

    2015-12-01

    a divisionalized bureaucracy (Mintzberg 1981). Designed as an innovation center, it is responsible for, among other things, forecasting and...the system, which prioritizes the needs and selection criteria for that system. 14. SUBJECT TERMS knowledge superiority, innovation , organizational...competitive advantage, knowledge is the critical element needed for any organization to innovate and succeed (Porter and Millar 1985). Its timely and

  14. Radiologic classification of superior canal dehiscence : Implications for surgical repair

    NARCIS (Netherlands)

    Lookabaugh, Sarah; Kelly, Hillary R.; Carter, Margaret S.; Niesten, Marlien E F; McKenna, Michael J.; Curtin, Hugh; Lee, Daniel J.

    2015-01-01

    Objective: Surgical access to repair a superior canal dehiscence (SCD) is influenced by the location of the bony defect and its relationship to surrounding tegmen topography as seen on computed tomography. There are currently no agreed-upon methods of characterizing these radiologic findings. We

  15. Mnemonic Training Reshapes Brain Networks to Support Superior Memory

    NARCIS (Netherlands)

    Dresler, M.; Shirer, W.R.; Konrad, B.N.; Muller, N.C.J.; Wagner, I.; Fernandez, G.S.E.; Czisch, M.; Greicius, M.D.

    2017-01-01

    Memory skills strongly differ across the general population; however, little is known about the brain characteristics supporting superior memory performance. Here we assess functional brain network organization of 23 of the world's most successful memory athletes and matched controls with fMRI

  16. Perturbation resilience and superiorization methodology of averaged mappings

    Science.gov (United States)

    He, Hongjin; Xu, Hong-Kun

    2017-04-01

    We first prove the bounded perturbation resilience for the successive fixed point algorithm of averaged mappings, which extends the string-averaging projection and block-iterative projection methods. We then apply the superiorization methodology to a constrained convex minimization problem where the constraint set is the intersection of fixed point sets of a finite family of averaged mappings.

  17. Measurement of ocular torsion variation following superior oblique tenectomy

    Directory of Open Access Journals (Sweden)

    Bruna Lana Ducca

    2014-12-01

    Full Text Available Purposes: To objectively evaluate the torsional effect of the superior oblique muscle-weakening surgery using the tenectomy technique proposed by Souza-Dias. Methods: The present prospective study included 10 patients (20 eyes with horizontal strabismus, bilateral superior oblique overaction and A-pattern of 15 to 30 prism diopters who underwent superior oblique tenectomy. Objective assessment of ocular torsion was performed by retinography immediately before and one month after surgery. The amount of ocular torsion was determined by measuring the angle formed by a horizontal line drawn across the geometric center of the optic disc and a second line connecting this point to the fovea. Results: The median preoperative angle was 5.56° in the right eyes and -3.43° in the left eyes. The median postoperative angle was 1.84° in the right eyes and -3.12° in the left eyes. The angle variation was statistically significant in both eyes (p=0.012 and p=0.01, respectively. Conclusion: The present study suggests that superior oblique tenectomy has an extorter effect, decreasing the intorsion detected on overaction of this muscle.

  18. Superior Mesenteric Artery Syndrome in a Young Military Basic Trainee

    Science.gov (United States)

    2013-03-01

    patients with severe anorexia nervosa .10 Severe cases may require surgery or parenteral feeding because of food avoidance leading to further loss of...2012. 10. Gwee K, Teh A, Huang C: Acute superior mesenteric artery syndrome and pancreatitis in anorexia nervosa . Australas Psychiatry 2010; 18(6): 523

  19. Morphological variation of siscowet lake trout in Lake Superior

    Science.gov (United States)

    Bronte, C.R.; Moore, S.A.

    2007-01-01

    Historically, Lake Superior has contained many morphologically distinct forms of the lake trout Salvelinus namaycush that have occupied specific depths and locations and spawned at specific times of the year. Today, as was probably the case historically, the siscowet morphotype is the most abundant. Recent interest in harvesting siscowets to extract oil containing omega-3 fatty acids will require additional knowledge of the biology and stock structure of these lightly exploited populations. The objective of this study was to determine whether shape differences exist among siscowet populations across Lake Superior and whether these shape differences can be used to infer stock structure. Morphometric analysis (truss protocol) was used to differentiate among siscowets sampled from 23 locations in Lake Superior. We analyzed 31 distance measurements among 14 anatomical landmarks taken from digital images of fish recorded in the field. Cluster analysis of size-corrected data separated fish into three geographic groups: The Isle Royale, eastern (Michigan), and western regions (Michigan). Finer scales of stock structure were also suggested. Discriminant function analysis demonstrated that head measurements contributed to most of the observed variation. Cross-validation classification rates indicated that 67–71% of individual fish were correctly classified to their region of capture. This is the first study to present shape differences associated with location within a lake trout morphotype in Lake Superior.

  20. El contexto virtual en la educación superior

    National Research Council Canada - National Science Library

    Vera Quintana, Mercedes

    2015-01-01

    ... técnicos, organizativos y metodológicos, por tanto, la virtualización de la educación superior durante su relativa corta vida, ha sido ese nuevo paradigma educativo resultante del uso de las tecnologías...

  1. Evaluation of the Superior Gluteal Nerve During Proximal Femoral Nailing

    Directory of Open Access Journals (Sweden)

    Mehmet Sonmez

    2017-05-01

    Full Text Available Aim: The superior gluteal nerve may be compromised during hip surgery. We retrospectively evaluated the patients who underwent proximal femoral nailing for unstable trochanteric fractures in order to investigate the presence of superior gluteal nerve injury and its clinical findings. Material and Method: Twenty five patients (14 women, 11 men were included in the study who had femoral nailing between January 2004 and March 2010 at Hamidiye Sisli Etfal Training and Research Hospital Department of Orthopaedics. Two different types of nails which have similar designs and surgical techniques were used for fracture fixation. Patients who had a history of cerebrovascular disease, electromyography findings of polyneuropathy, or degenerative vertebral disease were excluded from the study. Patients were evaluated clinically and radiologically. Findings related to acute denervation in the gluteus medius muscle and motor unit action potential changes were accepted as signs of superior gluteal nerve injury. Results: Eight patients were using support during walking and three of these patients had positive Trendelenburg sign, but only one patient had acute denervation signs of the superior gluteal nerve. Discussion: Based on the present study the incidence of iatrogenic nerve injury is a rare complication of proximal femoral nailing. Elderly patients, regardless of whether they have nerve injury, may limp and need to use a walking support.

  2. The effect of superior auditory skills on vocal accuracy

    Science.gov (United States)

    Amir, Ofer; Amir, Noam; Kishon-Rabin, Liat

    2003-02-01

    The relationship between auditory perception and vocal production has been typically investigated by evaluating the effect of either altered or degraded auditory feedback on speech production in either normal hearing or hearing-impaired individuals. Our goal in the present study was to examine this relationship in individuals with superior auditory abilities. Thirteen professional musicians and thirteen nonmusicians, with no vocal or singing training, participated in this study. For vocal production accuracy, subjects were presented with three tones. They were asked to reproduce the pitch using the vowel /a/. This procedure was repeated three times. The fundamental frequency of each production was measured using an autocorrelation pitch detection algorithm designed for this study. The musicians' superior auditory abilities (compared to the nonmusicians) were established in a frequency discrimination task reported elsewhere. Results indicate that (a) musicians had better vocal production accuracy than nonmusicians (production errors of 1/2 a semitone compared to 1.3 semitones, respectively); (b) frequency discrimination thresholds explain 43% of the variance of the production data, and (c) all subjects with superior frequency discrimination thresholds showed accurate vocal production; the reverse relationship, however, does not hold true. In this study we provide empirical evidence to the importance of auditory feedback on vocal production in listeners with superior auditory skills.

  3. Visuospatial Superiority in Developmental Dyslexia: Myth or Reality?

    Science.gov (United States)

    Brunswick, Nicola; Martin, G. Neil; Marzano, Lisa

    2010-01-01

    Anecdotal evidence indicates that dyslexia is positively associated with superior visuospatial ability but empirical evidence is inconsistent. We explicitly tested the hypothesis that dyslexia is associated with visuospatial advantage in 20 dyslexic and 21 unimpaired adult readers using paper-and-pencil measures and tests of "everyday"…

  4. Early detection of non-indigenous fishes in Lake Superior

    Science.gov (United States)

    Invasive species pose a serious threat to the ecological stability of the Great Lakes warranting continual monitoring for the arrival of new species. Three locations in Lake Superior were identified as “high risk” for new introductions: St. Louis River near Duluth, M...

  5. Preference for concentric orientations in the mouse superior colliculus

    NARCIS (Netherlands)

    Ahmadlou, Mehran; Heimel, J Alexander

    2015-01-01

    The superior colliculus is a layered structure important for body- and gaze-orienting responses. Its superficial layer is, next to the lateral geniculate nucleus, the second major target of retinal ganglion axons and is retinotopically organized. Here we show that in the mouse there is also a

  6. Funciones superiores en pacientes con accidente cerebro vascular

    National Research Council Canada - National Science Library

    Felipe Rodríguez; Alfonso Urzúa

    2009-01-01

    .... Con base a esto el objetivo de esta investigación fue elaborar un perfil de deterioro neuropsicológico de las diversas funciones cerebrales superiores causado por un ACV, en un grupo de 50 pacientes de la Unidad de Medicina...

  7. Absence of the superior petrosal veins and sinus: Surgical considerations

    Directory of Open Access Journals (Sweden)

    Ken Matsushima

    2015-01-01

    Conclusions: In cases in which the superior petrosal sinus and veins are absent, care should be directed to preserving the collateral drainage through the galenic and tentorial tributaries. Although surgical strategies for intraoperative management and preservation of venous structures are still controversial, knowledge of the possible anatomical variations is considered to be essential to improve surgical outcomes.

  8. Lake Superior supports novel clusters of cyanobacterial picoplankton.

    Science.gov (United States)

    Ivanikova, Natalia V; Popels, Linda C; McKay, R Michael L; Bullerjahn, George S

    2007-06-01

    Very little is known about the biodiversity of freshwater autotrophic picoplankton (APP) in the Laurentian Great Lakes, a system comprising 20% of the world's lacustrine freshwater. In this study, the genetic diversity of Lake Superior APP was examined by analyzing 16S rRNA gene and cpcBA PCR amplicons from water samples. By neighbor joining, the majority of 16S rRNA gene sequences clustered within the "picocyanobacterial clade" consisting of freshwater and marine Synechococcus and Prochlorococcus. Two new groups of Synechococcus spp., the pelagic Lake Superior clusters I and II, do not group with any of the known freshwater picocyanobacterial clusters and were the most abundant species (50 to 90% of the sequences) in samples collected from offshore Lake Superior stations. Conversely, at station Portage Deep (PD), located in a nearshore urbanized area, only 4% of the sequences belonged to these clusters and the remaining clones reflected the freshwater Synechococcus diversity described previously at sites throughout the world. Supporting the 16S rRNA gene data, the cpcBA library from nearshore station PD revealed a cosmopolitan diversity, whereas the majority of the cpcBA sequences (97.6%) from pelagic station CD1 fell within a unique Lake Superior cluster. Thus far, these picocyanobacteria have not been cultured, although their phylogenetic assignment suggests that they are phycoerythrin (PE) rich, consistent with the observation that PE-rich APP dominate Lake Superior picoplankton. Lastly, flow cytometry revealed that the summertime APP can exceed 10(5) cells ml-1 and suggests that the APP shifts from a community of PE and phycocyanin-rich picocyanobacteria and picoeukaryotes in winter to a PE-rich community in summer.

  9. [Examination of the hypothesis 'the factors and mechanisms of superiority'].

    Science.gov (United States)

    Sierra-Fitzgerald, O; Quevedo-Caicedo, J; López-Calderón, M G

    INTRODUCTION. The hypothesis of Geschwind and Galaburda suggests that specific cognitive superiority arises as a result of an alteration in development of the nervous system. In this article we review the co existence of superiority and inferiority . PATIENTS AND METHODS. A study was made of six children aged between 6 and 8 years old at the Instituto de Belles Artes Antonio Maria Valencia in Cali,Columbia with an educational level between second and third grade at a primary school and of medium low socio economic status. The children were considered to have superior musical ability by music experts, which is the way in which the concept of superiority was to be tested. The concept of inferiority was tested by neuropsychological tests = 1.5 DE below normal for the same age. We estimated the perinatal neurological risk in each case. Subsequently the children s general intelligence and specific cognitive abilities were evaluated. In the first case the WISC R and MSCA were used. The neuropsychological profiles were obtained by broad evaluation using a verbal fluency test, a test using counters, Boston vocabulary test, the Wechster memory scale, sequential verbal memory test, super imposed figures test, Piaget Head battery, Rey Osterrieth complex figure and the Wisconsin card classification test. The RESULTS showed slight/moderate deficits in practical construction ability and mild defects of memory and concept abilities. In general the results supported the hypothesis tested. The mechanisms of superiority proposed in the classical hypothesis mainly involve the contralateral hemisphere: in this study the ipsilateral mechanism was more important.

  10. Bioaccumulation of toxaphene congeners in the lake superior food web

    Science.gov (United States)

    Muir, D.C.G.; Whittle, D.M.; De Vault, D. S.; Bronte, C.R.; Karlsson, H.; Backus, S.; Teixeira, C.

    2004-01-01

    The bioaccumulation and biotransformation of toxaphene was examined in the food webs of Lake Superior and Siskiwit Lake (Isle Royale) using congener specific analysis as well as stable isotope ratios of carbon and nitrogen to characterize food webs. Toxaphene concentrations (calculated using technical toxaphene) in lake trout (Salvelinus namaycush) from the western basin of Lake Superior (N = 95) averaged (±SD) 889 ± 896 ng/g wet wt and 60 ± 34 ng/g wet wt in Siskiwit Lake. Major congeners in lake trout were B8-789 (P38), B8-2226 (P44), B9-1679 (P50), and B9-1025 (P62). Toxaphene concentrations were found to vary seasonally, especially in lower food web organisms in Lake Superior and to a lesser extent in Siskiwit Lake. Toxaphene concentrations declined significantly in lake herring (Coregonus artedii), rainbow smelt (Omerus mordax), and slimy sculpin (Cottus cognatus) as well as in zooplankton (> 102 &mn;m) and Mysis (Mysis relicta) between May and October. The seasonal variation may reflect seasonal shifts in the species abundance within the zooplankton community. Trophic magnification factors (TMF) derived from regressions of toxaphene congener concentrations versus δ15N were > 1 for most octa- and nonachlorobornanes in Lake Superior except B8-1413 (P26) and B9-715. Log bioaccumulation factors (BAFs) for toxaphene congeners in lake trout (ng/g lipid/ng/L dissolved) ranged from 4.54 to 9.7 and were significantly correlated with log octanol-water partition coefficients. TMFs observed for total toxaphene and congener B9-1679 in Lake Superior were similar to those in Arctic lakes, as well as to previous studies in the Great Lakes, which suggests that the bioaccumulation behavior of toxaphene is similar in pelagic food webs of large, cold water systems. However, toxaphene concentrations were lower in lake trout from Siskiwit Lake and lakes in northwestern Ontario than in Lake Superior possibly because of shorter food chains and greater reliance on zooplankton or

  11. Can linear superiorization be useful for linear optimization problems?

    Science.gov (United States)

    Censor, Yair

    2017-04-01

    Linear superiorization (LinSup) considers linear programming problems but instead of attempting to solve them with linear optimization methods it employs perturbation resilient feasibility-seeking algorithms and steers them toward reduced (not necessarily minimal) target function values. The two questions that we set out to explore experimentally are: (i) does LinSup provide a feasible point whose linear target function value is lower than that obtained by running the same feasibility-seeking algorithm without superiorization under identical conditions? (ii) How does LinSup fare in comparison with the Simplex method for solving linear programming problems? Based on our computational experiments presented here, the answers to these two questions are: ‘yes’ and ‘very well’, respectively.

  12. Anterior superior instability with rotator cuff tearing: SLAC lesion.

    Science.gov (United States)

    Savoie, F H; Field, L D; Atchinson, S

    2001-07-01

    Anterosuperior instability of the shoulder may occur from a variety of pathologic lesions. We describe a specific entity, the SLAC (superior labrum, anterior cuff) lesion that involves an association of anterior-superior labral tear with a partial supraspinatus tear. We retrospectively isolated a group of 40 patients with this lesion. The presenting complaints, physical examination findings, surgical findings, and results were isolated. Overhead activities were the most common etiology; load and shift instability testing and whipple rotator cuff testing were the most common physical examination findings. Surgical repair was successful in 37 of the 40 patients. The SLAC lesion is a definable clinical entity with predictable history, examination, surgical pathology, and satisfactory results from surgery.

  13. Superior gluteal nerve entrapment between two bellies of piriformis muscle

    Directory of Open Access Journals (Sweden)

    Yadav Y

    2010-12-01

    Full Text Available A double belly composition of piriformis muscle with superior gluteal nerve entrapment between the two muscle masses was detected. Piriformis muscle and its relation to sciatic nerve has been suggested as a cause of piriformis syndrome. Patients suffering from buttock pain are most often diagnosed as having piriformis syndrome, where anatomical variation of the piriformis is an important contributor. The present variation showed two distinct bellies of piriformis muscle. Interestingly the superior gluteal nerve was interposed between the two bellies. Such incidental findings on cadavers may help the clinicians to establish a rare yet important cause of piriformis syndrome. Furthermore, such observations are also relevant to the radiologists while interpreting MRI scans in cases of undiagnosed chronic gluteal pain.

  14. Laparoscopic Pancreaticoduodenectomy: Right Posterior Superior Mesenteric Artery "First" Approach.

    Science.gov (United States)

    Pittau, Gabriella; Sànchez-Cabùs, Santiago; Laurenzi, Andrea; Gelli, Maximiliano; Cunha, Antonio Sa

    2015-12-01

    Pancreaticoduodenectomy (PD) is considered one of the most challenging abdominal operations for several reasons, including the anatomy, which is surrounded by vital vascular structures and also because of the serious complications that are possible in the postoperative period. Nowadays, thanks to the development of minimally invasive surgery and improvement of patients' selection, laparoscopic pancreatic resections have been proven to be technically feasible and safe especially in the case of left pancreatectomies. More recently, many series of laparoscopic PD for adenocarcinoma have been published demonstrating the feasibility of this technique. In pancreatic cancer, the advantage of superior mesenteric artery "first approach" is already known to achieve an oncological resection. The purpose of this video is to describe the different technical aspects of the laparoscopic superior mesenteric artery first approach in the right posterior fashion.

  15. Surgical approach to the superior mid-orbit.

    Science.gov (United States)

    Krohn-Hansen, Dag; Nicolaissen, Bjørn; Meling, Torstein R; Haaskjold, Erling

    2013-09-01

    Access to the superior mid-orbit is required for procedures on the levator muscle in the correction of upper eyelid ptosis and in surgery aimed at local lesions in this region. The purpose with this human cadaver study was to clarify the anatomical substrate for a surgical approach to the levator muscle and the upper mid-orbit structures, in which the orbital septum and the retroseptal fat pad is not harmed during surgery. Macro-anatomical dissections and histological examinations were performed on five human orbits from three formalin embalmed cadaver heads. It was found that the orbital septum extends posteriorly from its junction with the levator aponeurosis. This posterior continuation of the orbital septum encloses the superior orbital fat pad and separates this from the anterior surface of the levator muscle. In between the orbital septum and the levator, there is a dissection space that provides a minimal invasive access corridor to the structures in the upper mid-orbit.

  16. False memories in highly superior autobiographical memory individuals.

    Science.gov (United States)

    Patihis, Lawrence; Frenda, Steven J; LePort, Aurora K R; Petersen, Nicole; Nichols, Rebecca M; Stark, Craig E L; McGaugh, James L; Loftus, Elizabeth F

    2013-12-24

    The recent identification of highly superior autobiographical memory (HSAM) raised the possibility that there may be individuals who are immune to memory distortions. We measured HSAM participants' and age- and sex-matched controls' susceptibility to false memories using several research paradigms. HSAM participants and controls were both susceptible to false recognition of nonpresented critical lure words in an associative word-list task. In a misinformation task, HSAM participants showed higher overall false memory compared with that of controls for details in a photographic slideshow. HSAM participants were equally as likely as controls to mistakenly report they had seen nonexistent footage of a plane crash. Finding false memories in a superior-memory group suggests that malleable reconstructive mechanisms may be fundamental to episodic remembering. Paradoxically, HSAM individuals may retrieve abundant and accurate autobiographical memories using fallible reconstructive processes.

  17. Genomes for jeans: cotton genomics for engineering superior fiber.

    Science.gov (United States)

    Mansoor, Shahid; Paterson, Andrew H

    2012-10-01

    Twenty years ago, scientists predicted that better understanding of fiber development would lead to novel ways to engineer superior cotton fiber. Advances in genetic resources, DNA markers, DNA sequence information, and gene expression data have indeed provided new insights into fiber initiation, elongation and maturation. Many exciting applications of this knowledge offer the potential to select better cotton genotypes more effectively in mainstream breeding programs or engineer genotypes with improved agronomic and/or quality traits. Here, we discuss recent progress in understanding genes involved in fiber development, and their regulation and manipulation to engineer improved fibers. Better understanding of quantitative trait loci/gene interactions that influence fiber quality and yield may help to tailor superior cotton genotypes to diverse environments.

  18. Tullio phenomenon in superior semicircular canal dehiscence syndrome.

    Science.gov (United States)

    Basura, Gregory J; Cronin, Scott J; Heidenreich, Katherine D

    2014-03-18

    Tullio phenomenon refers to eye movements induced by sound.(1) This unusual examination finding may be seen in superior semicircular canal dehiscence (SSCD) syndrome.(2) This disorder is due to absent bone over the superior semicircular canal (figure). Patients complain of dizziness triggered by loud sound, aural fullness, autophony, and pulsatile tinnitus. When Tullio phenomenon exists in SSCD syndrome, the patient develops a mixed vertical-torsional nystagmus in which the slow phase rotates up and away from the affected ear (video on the Neurology® Web site at Neurology.org). This pattern of nystagmus aligns in the plane of the dehiscent semicircular canal and is due to excitation of its afferent nerves.

  19. CURRENT COLLOIDAL DISPERSION GELS ARE NOT SUPERIOR TO POLYMER FLOODING

    Institute of Scientific and Technical Information of China (English)

    Seright Randy; Han Peihui; Wang Dongmei

    2006-01-01

    The suggestion that the colloidal-dispersion-gel (CDG) process is superior to normal polymer flooding is misleading and generally incorrect. Colloidal dispersion gels, in their present state of technological development, should not be advocated as an improvement to, or substitute for, polymer flooding. Gels made from aluminum-citrate crosslinked polyacrylamides can act as conventional gels and provide effective conformance improvement in treating some types of excess water production problems if sound scientific and engineering principles are respected.

  20. Pseudoaneurysm of the superior gluteal artery following polytrauma

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dennis [Vancouver General Hospital, University of British Columbia and Department of Radiology, Vancouver, BC (Canada); Legiehn, Gerald M. [Vancouver General Hospital, Interventional Radiology, University of British Columbia and Department of Radiology, Vancouver, BC (Canada); Munk, Peter L. [Vancouver General Hospital, MSK Section, University of British Columbia and Department of Radiology, Vancouver, BC (Canada)

    2007-09-15

    Gluteal artery aneurysms are rare and often secondary to pelvic fractures, blunt or penetrating trauma. We describe a case of a superior gluteal artery pseudoaneurysm that presented as back pain with numbness and weakness of the lower extremities. Diagnosis was confirmed by color Doppler sonography and angiography. A proximal and distal control was obtained over the aneurysm neck via coil embolization with excellent hemostasis within the pseudoaneurysm and maintenance of perfusion to the left pelvis. (orig.)

  1. [Superior gluteal nerve: a new block on the block?

    Science.gov (United States)

    Sá, Miguel; Graça, Rita; Reis, Hugo; Cardoso, José Miguel; Sampaio, José; Pinheiro, Célia; Machado, Duarte

    2017-05-24

    The superior gluteal nerve is responsible for innervating the gluteus medius, gluteus minimus and tensor fascia latae muscles, all of which can be injured during surgical procedures. We describe an ultrasound-guided approach to block the superior gluteal nerve which allowed us to provide efficient analgesia and anesthesia for two orthopedic procedures, in a patient who had significant risk factors for neuraxial techniques and deep peripheral nerve blocks. An 84-year-old female whose regular use of clopidogrel contraindicated neuraxial techniques or deep peripheral nerve blocks presented for urgent bipolar hemiarthroplasty in our hospital. Taking into consideration the surgical approach chosen by the orthopedic team, we set to use a combination of general anesthesia and superficial peripheral nerve blocks (femoral, lateral cutaneous of thigh and superior gluteal nerve) for the procedure. A month and a half post-discharge the patient was re-admitted for debriding and correction of suture dehiscence; we performed the same blocks and light sedation. She remained comfortable in both cases, and reported no pain in the post-operative period. Deep understanding of anatomy and innervation empowers anesthesiologists to solve potentially complex cases with safer, albeit creative, approaches. The relevance of this block in this case arises from its innervation of the gluteus medius muscle and posterolateral portion of the hip joint. To the best of our knowledge, this is the first report of an ultrasound-guided superior gluteal nerve block with an analgesic and anesthetic goal, which was successfully achieved. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  2. Superior gluteal nerve entrapment between two bellies of piriformis muscle

    OpenAIRE

    Yadav Y; Mehta V; Roy S; Suri R; Rath G

    2010-01-01

    A double belly composition of piriformis muscle with superior gluteal nerve entrapment between the two muscle masses was detected. Piriformis muscle and its relation to sciatic nerve has been suggested as a cause of piriformis syndrome. Patients suffering from buttock pain are most often diagnosed as having piriformis syndrome, where anatomical variation of the piriformis is an important contributor. The present variation showed two distinct bellies of piriformis muscle. Interestingly the sup...

  3. Pseudoaneurysm of the superior gluteal artery following polytrauma.

    Science.gov (United States)

    Lee, Dennis; Legiehn, Gerald M; Munk, Peter L

    2007-09-01

    Gluteal artery aneurysms are rare and often secondary to pelvic fractures, blunt or penetrating trauma. We describe a case of a superior gluteal artery pseudoaneurysm that presented as back pain with numbness and weakness of the lower extremities. Diagnosis was confirmed by color Doppler sonography and angiography. A proximal and distal control was obtained over the aneurysm neck via coil embolization with excellent hemostasis within the pseudoaneurysm and maintenance of perfusion to the left pelvis.

  4. Superior vesical fissure concealed by giant omphalocele: A case report

    Directory of Open Access Journals (Sweden)

    Danial Hayek

    2016-11-01

    Full Text Available Omphalocele is an abdominal wall defect characterized by exteriorization of abdominal viscera that is covered by a membrane. Omphalocele has a well-known association with chromosome abnormalities. Here we present a case of a superior vesical fissure (SVF initially disguised as a giant omphalocele in a newborn with trisomy 18. We also show unique prenatal imaging and discuss the importance and limitations of prenatal genetic testing.

  5. Information Superiority generated through proper application of Geoinformatics

    Science.gov (United States)

    Teichmann, F.

    2012-04-01

    Information Superiority generated through proper application of Geoinformatics Information management and especially geoscience information delivery is a very delicate task. If it is carried out successfully, geoscientific data will provide the main foundation of Information Superiority. However, improper implementation of geodata generation, assimilation, distribution or storage will not only waste valuable resources like manpower or money, but could also give rise to crucial deficiency in knowledge and might lead to potentially extremely harmful disasters or wrong decisions. Comprehensive Approach, Effect Based Operations and Network Enabled Capabilities are the current buzz terms in the security regime. However, they also apply to various interdisciplinary tasks like catastrophe relief missions, civil task operations or even in day to day business operations where geo-science data is used. Based on experience in the application of geoscience data for defence applications the following procedure or tool box for generating geodata should lead to the desired information superiority: 1. Understand and analyse the mission, the task and the environment for which the geodata is needed 2. Carry out a Information Exchange Requirement between the user or customer and the geodata provider 3. Implementation of current interoperability standards and a coherent metadata structure 4. Execute innovative data generation, data provision, data assimilation and data storage 5. Apply a cost-effective and reasonable data life cycle 6. Implement IT security by focusing of the three pillar concepts Integrity, Availability and Confidentiality of the critical data 7. Draft and execute a service level agreement or a memorandum of understanding between the involved parties 8. Execute a Continuous Improvement Cycle These ideas from the IT world should be transferred into the geoscience community and applied in a wide set of scenarios. A standardized approach of how to generate, provide

  6. Superior Mesenteric Artery Syndrome: An Infrequent Complication of Scoliosis Surgery

    OpenAIRE

    Metin Keskin; Turgut Akgül; Adem Bayraktar; Fatih Dikici; Emre Balık

    2014-01-01

    Case Report Superior Mesenteric Artery Syndrome: An Infrequent Complication of Scoliosis Surgery Metin Keskin,1 Turgut Akgül,2 Adem Bayraktar,1 Fatih Dikici,2 and Emre BalJk3 1 General Surgery Department, Istanbul Faculty of Medicine, Istanbul University, Capa, Millet Caddesi, 34093 Istanbul, Turkey 2Orthopedic Department, Istanbul Faculty of Medicine, Istanbul University, Capa, Millet Caddesi, 34093 Istanbul, Turkey 3 General Surgery Department, School of Medicine, Koc¸ Uni...

  7. São os membros superiores na Paralisia Cerebral negligenciados?

    Directory of Open Access Journals (Sweden)

    Ubiratan Brum Castro

    2014-06-01

    Full Text Available Objetivo: Avaliar se num serviço de atendimento especializado, o membro superior é preterido ou negligenciado no tratamento das alterações motoras da Paralisia Cerebral. Casuística e métodos: Foram analisados 80 pacientes portadores de Paralisia Cerebral menores de dezessete anos tratados institucionalmente. Foram avaliados pelo mesmo examinador quanto à classificação e tratamentos (cirúrgico ou não do aparelho locomotor. Resultados: O membro superior teve a seguinte abordagem terapêutica considerando o grupo de mão comprometida, 1 (2% foi submetido a transferência tendinosa no punho e 53 (98% não foram operados. Quanto a órteses, 9 (17% usavam estabilizadores de punho e 45 (83% não usavam. Quanto à toxina botulínica não houve aplicação nos membros superiores. Nos membros inferiores, considerando o total de pacientes, 16 (20% foram submetidos à cirurgia e 64(80% não foram operados. As cirurgias foram um tratamento cirúrgico de luxação do quadril, 7 a alongamentos múltiplos em membros inferiores, 5 alongamento de tendão calcâneo, 3 tenotomia de adutores. Quanto ao uso de órteses, 49 (61% faziam uso e 31(39% não utilizavam. Dos pacientes que faziam uso de órteses, 48 usavam tala estabilizadora de tornozelo, um usava estabilizador de joelho. Quanto à  o uso de toxina botulínica: 32 tiveram aplicação (40% e 48 não receberam aplicação (60%. Conclusão: No presente estudo, o tratamento do membro superior foi negligenciado.

  8. Effect of bilateral superior oblique split lengthening on torsion

    Directory of Open Access Journals (Sweden)

    Jitendra Jethani

    2015-01-01

    Full Text Available Introduction: Superior oblique split lengthening (SOSL is done for weakening of superior oblique. It corrects the superior oblique overaction (SOOA and A pattern. Its effect on the torsion of the eye is not known. We present our data on the effect of this particular procedure on torsion. Materials and Methods: We did a study of 16 patients (32 eyes who underwent bilateral SOSL and compared the disc foveal angle (DFA preoperatively and postoperatively. The split lengthening was done from 4 mm to 7 mm depending upon the overaction of superior oblique. Results: The mean age was 15.3 ± 8.4 years. Mean preoperative DFA in the right eye (RE was −3.9° and in the left eye (LE was −2.9°. Mean postoperative DFA in RE was 0.2° and in LE was 0.9°. The mean change in the DFA for RE was 4.1° ± 1.3° and for LE was 3.8° ± 1.2°. All the patients were aligned horizontally within 6 prism diopter and no pattern and no diplopia postoperatively. The A pattern was corrected in all the patient postsurgery. For each mm of surgery, an improvement of 0.8° was seen in the DFA. Conclusion: We report the effect of SOSL on torsion. The SOSL reduces intorsion postsurgery and is, therefore, a valuable procedure in SOOA where both pattern and in torsion needs to be corrected.

  9. A Rare Complication of Acute Appendicitis: Superior Mesenteric Vein Thrombosis

    Directory of Open Access Journals (Sweden)

    Hendra Koncoro

    2016-12-01

    Full Text Available Superior mesenteric vein (SMV thrombosis caused by acute appendicitis is quite rare nowadays. These conditions occurs secondary to infection in the region drained by the portal venous system. In this case, we report a successfully treated case of SMV thrombosis and liver abscess associated with appendicitis with antibiotics and anticoagulant.Early diagnosis and prompt treatment are basic to a favorable clinical course.

  10. Superior Gas Sensing Properties of Monolayer PtSe2

    KAUST Repository

    Sajjad, Muhammad

    2016-12-15

    First-principles calculations of the structural and electronic properties of monolayer 1T-PtSe2 with adsorbed (a) NO2, (b) NO, (c) NH3, (d) H2O, (e) CO2, and (f) CO molecules are discussed. The results point to great potential of the material in gas sensor applications. Superior sensitivity is demonstrated by transport calculations using the nonequilibrium Green\\'s function method.

  11. Superior parathyroid gland approach to the recurrent laryngeal nerve.

    Science.gov (United States)

    Elsheikh, Ezzeddin

    2017-07-01

    The superior parathyroid gland is known to be almost constant in its location under the false thyroid capsule. Could it be a landmark to point to the site of incision of the false thyroid capsule and find the plane of the recurrent laryngeal nerve (RLN) during thyroidectomy? The study included 48 patients with benign goiter scheduled for hemithyroidectomy or total thyroidectomy; there were 16 cases of solitary thyroid nodules, 27 cases of multinodular goiter, and 5 cases of toxic goiter. This study included 80 lobectomies. All patients showed no evidence of postoperative RLN palsy, bleeding, or hypoparathyroidism. The superior parathyroid gland was consistently found within the false capsule in all cases, whereas the inferior parathyroid was found within the same layer in 64 sides (80%). The described approach can accurately guide dissection between true and false capsules of the thyroid to reach and preserve both the RLN and the superior parathyroid gland. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1287-1290, 2017. © 2017 Wiley Periodicals, Inc.

  12. Hacia una educación superior inclusiva en Colombia

    Directory of Open Access Journals (Sweden)

    Sandra Lucia Arizabaleta Dominguez

    2016-12-01

    Full Text Available En este artículo se analizan concepciones teórico-conceptuales básicas que subyacen a la educación superior inclusiva, en el marco de los Lineamientos de la Política de Educación Superior Inclusiva del Ministerio de Educación Nacional de Colombia (men. Además, se plantean los desafíos que deben asumir las instituciones de educación superior (ies en la identificación de barreras de aprendizaje de su población estudiantil y la promoción de estrategias que garanticen la accesibilidad, permanencia, pertinencia académica y la graduación. Esta situación lleva a las ies a reflexionar y repensarse a partir de los procesos de autoevaluación institucional para crear estrategias participativas que promuevan la gestión inclusiva en un sistema educativo equitativo, pertinente y de calidad

  13. Anatomo-radiological study of the Superior Semicircular Canal Dehiscence

    Energy Technology Data Exchange (ETDEWEB)

    Crovetto, M., E-mail: macdlt@telefonica.net [Otolaryngology Department, Hospital de Basurto, University of the Basque Country, Avenida de Montevideo 18, Bilbao 48013, Vizcaya (Spain); Whyte, J., E-mail: jwhite@unizar.es [Faculty of Medicine, Department of Human Anatomy and Histology, University of Zaragoza, C/Domingo Mirall s/n, Zaragoza (Spain); Rodriguez, O.M., E-mail: OLIVIAMARIA.RODRIGUEZSANVICENT@osakidetza.net [Hospital de Cruces, Baracaldo, Vizcaya (Spain); Lecumberri, I., E-mail: INIGO.LECUMBERRICORTES@osakidetza.net [Hospital de Basurto, Avenida Montevideo 18, Bilbao 498013 (Spain); Martinez, C., E-mail: claudiorayosx@yahoo.es [Hospital General de la Defensa, Via Iberica s/n Zaragoza (Spain); Elexpuru, J., E-mail: jelexpuru@mac.com [Hospital de Basurto, Avenida de Montevideo 18, Bilbao 48013, Vizcaya (Spain)

    2010-11-15

    Introduction: The main purpose of this study is to determine the radiological incidence of Superior (SSCD) and Posterior Semicircular Canal Dehiscence (PSCD) and to compare radiologic SSCD to the incidence of this condition on cadaver specimen. We have also analysed the relation between the ossification state of the semicircular canals and the degree of mastoid pneumatization and integrity of Tegmen Tympani. Material and methods: Temporal bones have been investigated by means of CT scan on patients and direct observation on cadaver specimen, respectively. Results: 604 ears and 160 cadaver temporal bones have been investigated by means of CT scan and direct observation, respectively. 3.6% and 0.3% of the studied ears had SSCD and PSCD, respectively, on CT scan. Only 0.6% of the cadaver specimen ears did have anatomical SSCD. Degree of pneumatization of the mastoid bone is related to the mean thickness of bone overlying the Superior and Posterior Semicircular Canal. Radiological absence of Tegmen Tympani is more frequent in ears that also have radiologic SSCD. Conclusion: CT scanning gives higher incidence figures of SSCD than anatomical studies, 3.6% vs. 0.6%. We also found a 0.6% incidence of radiological PSCD in the studied ears. There is a direct relation between the degree of ossification of Superior and Posterior Semicircular Canal and certain temporal bone anatomic features: temporal bone pneumatization and absence/presence of Tegmen Tympani or Antri.

  14. Relative superiority analysis of Garut lamb and its crossbred

    Directory of Open Access Journals (Sweden)

    Ismeth Inounu

    2003-10-01

    Full Text Available The objective of the research was to evaluate the relative superiority of Garut lamb and its crosses with St. Croix and Moulton Charollais. The research was conducted at Animal Research Station, Indonesian Research Institute for Animal Production, Bogor, Indonesia. The data used for this paper was collected from 1995 to 2002. The results revealed that individual lamb weight at birth, at weaning, preweaning daily gain, at 6, 9 and 12 months of age of the composite sheep (HG = 50% St. Croix : 50% Garut, MG = 50% M. Charollais : 50% Garut, MHG (MG X HG dan HMG (HG X MG = 25% St. Croix : 25% M. Charollais : 50% Garut were higher than Garut sheep. The relative superiority were 6.7-13.1% for lamb weight at birth, 6.6- 15.6% for lamb weight at weaning, 3.2-20.8% for preweaning daily gain dan 6.2-17.9% for lamb weight at 9 month of age, respectively. The superiority of composite sheep were obtained in good and limited feed condition. Lamb growth parameters were also affected by feed condition, parity, sex, and rearing type.

  15. Superior metallic alloys through rapid solidification processing (RSP) by design

    Energy Technology Data Exchange (ETDEWEB)

    Flinn, J.E. [Idaho National Engineering Laboratory, Idaho Falls, ID (United States)

    1995-05-01

    Rapid solidification processing using powder atomization methods and the control of minor elements such as oxygen, nitrogen, and carbon can provide metallic alloys with superior properties and performance compared to conventionally processing alloys. Previous studies on nickel- and iron-base superalloys have provided the baseline information to properly couple RSP with alloy composition, and, therefore, enable alloys to be designed for performance improvements. The RSP approach produces powders, which need to be consolidated into suitable monolithic forms. This normally involves canning, consolidation, and decanning of the powders. Canning/decanning is expensive and raises the fabrication cost significantly above that of conventional, ingot metallurgy production methods. The cost differential can be offset by the superior performance of the RSP metallic alloys. However, without the performance database, it is difficult to convince potential users to adopt the RSP approach. Spray casting of the atomized molten droplets into suitable preforms for subsequent fabrication can be cost competitive with conventional processing. If the fine and stable microstructural features observed for the RSP approach are preserved during spray casing, a cost competitive product can be obtained that has superior properties and performance that cannot be obtained by conventional methods.

  16. Stomatitis sub-prosthesis in patients with superior dental prosthesis

    Directory of Open Access Journals (Sweden)

    Antonia Martina Francisco Local

    2009-04-01

    Full Text Available Background: The stomatitis sub-prosthesis is one of the most frequent changes in hard palate mucous membrane in patients with mucous-supported dental prosthesis. It can be caused by multiple factors, which makes its study and prognosis more difficult. Objective: To describe the occurrence of stomatitis sub-prosthesis and its causes in patients with superior dental prosthesis. Method: Descriptive study including all the patients with superior dental prosthesis examined in the odontology consultation “Barrio Adentro” in the state of Miranda, Venezuela, from November, 2005 to March, 2006. The analysed variables were: age, sex, stomatitis level, teeth brushing frequency, prosthesis condition and use, palate mucous condition and frequency of odontology consultations. Results: 89 patients were attended, more 50% of them had superior dental prosthesis and presented stomatitis sub-prosthesis; the group between 35 and 59 years was the most affected, mainly females. Sub-prosthesis stomatitis type II was the most common and the main causes included constant use of the prosthesis and loose prosthesis. Buccal hygiene was not adequate in these patients. Most of them declared never attending to the dentist, or just when presenting some particular problem. Conclusion: Stomatitis prevalence was related with incorrect hygiene habits and lack of knowledge; it shows the importance of performing educative tasks to reduce this disease incidence.  

  17. Water quality of streams tributary to Lakes Superior and Michigan

    Science.gov (United States)

    Zimmerman, Jerome W.

    1968-01-01

    Water quality of streams tributary to Lakes Superior and Michigan was analyzed for 142 stations on 99 streams tributary to Lake Superior and 83 stations on 56 streams tributary to Lake Michigan during 1962-65. Concentrations of aluminum, copper, and iron were not affected greatly by flow or season. Magnesium, calcium, chlorides, total alkalinity, total hardness, and conductivity varied with the flow, temperature, and season; the lowest values were during the spring runoff and heavy rains, and the highest were during low water in late summer and the colder periods of winter. Concentrations of nitrate, silica, and sulfates were lowest in the spring and summer. Concentrations of tanninlike and ligninlike compounds were highest during the spring runoff and other high-water periods, and were lowest during freezeup when surface runoff was minimal. The pH values were highest from June to September and lowest during the spring runoff. Phenolphthalein alkalinity was detected primarily in the summer and coincided occasionally with low flows just before the spring thaw. Total hardness usually was lower in streams tributary to Lake Superior than in streams tributary to Lake Michigan. The total hardness was higher in the streams in Wisconsin than in the streams in Michigan along the west shore of Lake Michigan. It was lowest in the northernmost streams. The water quality of the streams in an area was related to the geological characteristics of the land.

  18. Cooperation between ligninolytic enzymes produced by superior mixed flora

    Institute of Scientific and Technical Information of China (English)

    WANG Hai-lei; LI Zong-yi; GUO Wei-yun; WANG Zhen-yu; PAN Feng

    2005-01-01

    Since the ability to degrade lignin with one kind of white-rot fungi or bacteria was very limited, superior mixed flora's ability to degrade lignin was investigated by an orthogonal experiment in this paper. The results showed that superior mixed flora reinforced the ability to degrade lignin, the degradation rates of both sample 9 and 10 were beyond 80% on the day 9. The cooperation between lignin peroxidase(LiP), Mn-dependent peroxidase(MnP) and laccase (Lac) for lignin degradation was also studied. By examining the activities of three enzymes produced by superior mixed flora, it was found that Lac was a key enzyme in the process of biological degradation of lignin but Lip was not; the enzyme activity ratios of Lac/MnP and Lac/LiP were significantly correlative with the degradation rate of lignin at the 0.01 level; and the ratio of MnP/LiP was an important factor affecting the degradation rate of lignin.

  19. Preference for Audiovisual Speech Congruency in Superior Temporal Cortex.

    Science.gov (United States)

    Lüttke, Claudia S; Ekman, Matthias; van Gerven, Marcel A J; de Lange, Floris P

    2016-01-01

    Auditory speech perception can be altered by concurrent visual information. The superior temporal cortex is an important combining site for this integration process. This area was previously found to be sensitive to audiovisual congruency. However, the direction of this congruency effect (i.e., stronger or weaker activity for congruent compared to incongruent stimulation) has been more equivocal. Here, we used fMRI to look at the neural responses of human participants during the McGurk illusion--in which auditory /aba/ and visual /aga/ inputs are fused to perceived /ada/--in a large homogenous sample of participants who consistently experienced this illusion. This enabled us to compare the neuronal responses during congruent audiovisual stimulation with incongruent audiovisual stimulation leading to the McGurk illusion while avoiding the possible confounding factor of sensory surprise that can occur when McGurk stimuli are only occasionally perceived. We found larger activity for congruent audiovisual stimuli than for incongruent (McGurk) stimuli in bilateral superior temporal cortex, extending into the primary auditory cortex. This finding suggests that superior temporal cortex prefers when auditory and visual input support the same representation.

  20. Síndrome da artéria mesentérica superior Superior mesenteric artery syndrome

    OpenAIRE

    Haberlandh Sodré Lima; Accyoli Moreira Maia; Antonio Kneipp Pitta de Castro Neto

    2000-01-01

    The Superior Mesenteric Syndrome is a rare and controversial disease. The compression of the duodenum by the mesenteric artery and aorta causes an intermitent obstruction. Preoperative diagnosis is very difficult.We present one case of this syndrome in a pacient with severe weight loss and signs of high intestinal obstruction. The diagnosis was based on clinical and radiologic findings. A duodenojejunostomy was performed after medical treatment failure.This patient died on the 20th posoperati...

  1. Decoding the superior parietal lobule connections of the superior longitudinal fasciculus/arcuate fasciculus in the human brain.

    Science.gov (United States)

    Kamali, A; Sair, H I; Radmanesh, A; Hasan, K M

    2014-09-26

    The temporo-parietal (TP) white matter connections between the inferior parietal lobule and superior temporal gyrus as part of the superior longitudinal fasciculus/arcuate fasciculus (SLF/AF) or middle longitudinal fasciculus (MdLF) have been studied in prior diffusion tensor tractography (DTT) studies. However, few studies have been focusing on the higher TP connections of the superior parietal lobule with the temporal lobe. These higher TP connections have been shown to have a role in core processes such as attention, memory, emotions, and language. Our most recent study, for the first time, hinted to the possibility of a long white matter connection interconnecting the superior parietal lobule (SPL) with the posterior temporal lobe in human brain which we call the SLF/AF TP-SPL and for a shorter abbreviation, the TP-SPL. We decided to further investigate this white matter connection using fiber assignment by continuous tracking deterministic tractography and high spatial resolution diffusion tensor imaging on 3T. Five healthy right-handed men (age range 24-37 years) were studied. We delineated the SPL connections of the SLF/AF TP bilaterally in five normal adult human brains. Using a high resolution DTT technique, we demonstrate for the first time, the trajectory of a long fiber bundle connectivity between the SPL and posterior temporal lobe, called the SLF/AF TP-SPL (or the TP-SPL), bilaterally in five healthy adult human brains. We also demonstrate the trajectory of the vertically oriented posterior TP connections, interconnecting the inferior parietal lobule (IPL) with the posterior temporal lobe (TP-IPL) in relation to the TP-SPL, arcuate fasciculus and other major language pathways. In the current study, for the first time, we categorized the TP connections into the anterior and posterior connectivity groups and subcategorized each one into the SPL or IPL connections. Published by Elsevier Ltd.

  2. THE HUMAN SUBJECTIVITY BETWEEN THE SUPERIOR AND INFERIOR TYPES A SUBJETIVIDADE HUMANA ENTRE OS TIPOS SUPERIORES E INFERIORES

    Directory of Open Access Journals (Sweden)

    Vagner Silva

    2011-12-01

    Full Text Available This article attempts to solve the following contradiction of Nietzsche's thought: man has a subjective drive constitution, these drives, however, are individuals, and its being (the being of the drives, is constituted for more power fight (the will to power. Nietzsche's superior man (educated and cultivated man is that one, in which there is harmony in the drives, who can give greater freedom to its most terrible drives, without, however, loses the control over them. That is the contradiction: if man has to control the drives, they are not harmonics. There is incompatibility between harmony and control. In other words, the superior man is indeed the man of culture and cultivated man of Nietzsche? If the answer to this question is yes, then, in this man, reigns the drives harmony. If, on the other hand, the answer is no, then, for this man does not become a barbarian destroyer, dangerous to himself and to others it is necessary that a drive dominates the others. However it is not possible to escape the contradiction: either there is harmony in human drive or control.Este artigo busca resolver a seguinte contradição do pensamento de Nietzsche: o homem possui uma constituição subjetiva pulsional, estas pulsões, porém, são individuais, e o seu ser, o das pulsões, constitui-se da luta por mais poder (vontade de poder. O homem superior de Nietzsche (homem culto e cultivado é aquele no qual há harmonia nas pulsões, aquele que pode dar mais liberdade às suas mais terríveis pulsões, sem, no entanto, perder o controle sobre elas. Eis a contradição: se o homem superior exerce controle sobre as pulsões então elas não são harmônicas. Há, aqui, a incompatibilidade entre harmonia e controle. Em outros termos: o homem superior é de fato o homem culto e cultivado de Nietzsche? Se a resposta para esta pergunta for sim, então neste homem reina a harmonia pulsional. Se, por outro lado, a resposta for não, então, para que este homem n

  3. Superior facet syndrome. Findings on metrizamide CT myelography

    Energy Technology Data Exchange (ETDEWEB)

    Kubo, Yoshichika; Igarashi, Seishi; Koyama, Tsunemaro

    1985-02-01

    Sciatica caused by root entrapment in the lateral recess was named superior facet syndrome by Epstein in 1972. Few reports on this subject based on large numbers of cases have been documented to date. Of the patients with sciatica, 32 patients were diagnosed to have root entrapment at the lateral recess L5 or/and S1 lumbar spine. Out of 32 patients, 20 patients were operated on and the lateral entrapment was recognized in all of surgical cases. Neuroradiological findings, especially of metrizamide CT (met. CT), were documented in detail. Thirty two patients were classified in three types according to radiological findings. They were congenital or developmental, degenerative, and combined type, respectively. Fourteen cases belonged to the congenital type, 13 to the degenerative and 5 to the combined type. Each group had the mean ages of 23.4, 53.8, and 36.8 years old, respectively. Of 32 cases the entrapment occured in 47 L5 roots and 11 S1 roots. There was no remarkable laterality. In operation the unroofing of the lateral recess were done and the sciatica subsided postoperatively in all of surgical cases. Met. CT revealed extreme medial protrusion of the superior articular joint in 18 of 24 cases(75%) and none filling of the root in the lateral recess in 21 of 24 cases (87.5%). In the degenerative type, met. CT showed some degenerative changes that were hypertrophy or deformity of the articular joints and spur formation of the vertebral body. In contrast to met. CT, metrizamide myelography revealed only slight changes, which were poor filling of the root before it turned out the pedicle of lateral compression of the root. In plain films or lumbar spine articular joints at Lsub(4/5) were formed in coronal plane in 69% of cases of the L5 root entrapment. Met. CT using ReView technique was of great diagnostic value in superior facet syndrome.

  4. QUAL DEMOCRATIZAÇÃO DO ENSINO SUPERIOR?

    Directory of Open Access Journals (Sweden)

    François Dubet

    Full Text Available Esse artigo, resultante de uma conferência, discute traços do processo de democratização do ensino superior. Procura distinguir analiticamente várias dimensões da democratização, baseadas, por sua vez, em concepções diferentes da justiça: igualdade de oportunidades, meritocracia, utilidades e equidade dos procedimentos. Cada sociedade constrói modelos de democratização desse ensino. A massificação do ensino superior desempenhou papel democrático objetivo, favorável aos grupos sociais antes excluídos. Mas massificação não equivale à democratização. Todas as categorias sociais não se beneficiam da mesma forma da massificação. A democratização do acesso ao ensino superior não depende apenas das famílias. Depende também da estrutura geral do sistema educativo. A meritocracia acadêmica constrói uma hierarquia de competências que é também social, com forte impacto reprodutivo. As desigualdades de utilidade das diferentes formações têm impacto sobre o conjunto das desigualdades sociais. Os sistemas educativos implementam distintos procedimentos de seleção, de concessão de gratuidades, bolsas e auxílios, que podem ser considerados como mais ou menos equitativos segundo as normas de justiça que mobilizam.

  5. Lipid peroxidation following superior mesenteric artery occlusion in rat intestine

    Directory of Open Access Journals (Sweden)

    P. Pasbakhsh

    2006-07-01

    Full Text Available Background: The aim of this study was to determine the level of lipid peroxidation and tissue protein after superior mesenteric artery occlusion tissue damage. The effect of melatonin as anti oxidant and free radical scavenger in prevention of tissue damage, were also evaluated. Methods: Thity six young male Wisatr-Albino rats (weight: 80-120 gr, were divided equally in 6 group with different concentrations of melatonin (10,20,30 mg/kg treatment. Group 1was control, group 2 the sham that surgical process was applied until superior mesenteric artery dissection and received vehicle solution only in equally volume by intra muscular route. Group 3 was ischemia- reperfusion (I/R, group 4 was I/R plus melatonin 10 mg/kg, group 5 I/R plus melatonin 20 mg/kg and finally group 6 I/R plus melatonin 30 mg/kg. After laparatomy, a microvascular atraumatic clip was placed across the superior mesenteric artery under general anaesthesia and itbremoved after ischemia for 30 minutes. The first dose of melatonin was applied just beforereperfusion, second dose, after reperfusion and third dose on the second day .On third day rats were killed and their bowels were removed. The level of tissue melandialdehyde (MDA as index of lipid peroxidation and tissue protein was determined. Results: The level of tissue MDA were significantly lower in group 4, 5, 6 than group 3 (p0, 05. Conclusion: These results suggest that melatonin 10 mg/kg has antioxidant effect in prevention of inducing tissue damage during SMA occlusion in rat intestine.

  6. LA EDUCACIÓN SUPERIOR CUBANA: LOGROS Y PERSPECTIVAS

    Directory of Open Access Journals (Sweden)

    Acela Cantero Zayas

    Full Text Available Resumen: El impetuoso desarrollo de la ciencia y la técnica contemporâneo en general y muy específicamente en la realidad cubana, estâ dirigido a satisfacer las necesidades creciente de nuestra sociedad, lo que conlleva a un continuo perfeccionamiento de todo el sistema educativo en correspondencia con las exigencias, demandas y necesidades de nuestro pueblo. En tal sentido, para comprender los resultados que exhibe la Educación cubana y dentro de ella la Educación Superior, se precisa de toda una reflexión histórica, como soporte lógico y metodológico del hecho educativo cubano. En la actualidad, el mayor impacto de nuestra Educación Superior, desde los puntos de vista social, político, económico y en especial formativo, lo constituye, el diseno e implementación del modelo de Universalización, el cual tiene como objetivo supremo la extensión de la Universidad a los distintos municipios del país, con la finalidad de irradiar cultura y saber, que son las únicas modalidades de garantizar un hombre libre y de hecho una sociedad independiente. En el presente trabajo se muestra una panorâmica de la Educación Superior en Cuba, partiendo del elemento histórico hasta la contemporaneidad y en ésta, los nuevos retos impuestos por el contexto socio-político a escala mundial.

  7. LA EDUCACIÓN SUPERIOR CUBANA: LOGROS Y PERSPECTIVAS

    Directory of Open Access Journals (Sweden)

    Acela Cantero Zayas

    2004-01-01

    Full Text Available El impetuoso desarrollo de la ciencia y la técnica contemporáneo en general y muy específicamente en la realidad cubana, está dirigido a satisfacer las necesidades creciente de nuestra sociedad, lo que conlleva a un continuo perfeccionamiento de todo el sistema educativo en correspondencia con las exigencias, demandas y necesidades de nuestro pueblo. En tal sentido, para comprender los resultados que exhibe la Educación cubana y dentro de ella la Educación Superior, se precisa de toda una reflexión histórica, como soporte lógico y metodológico del hecho educativo cubano. En la actualidad, el mayor impacto de nuestra Educación Superior, desde los puntos de vista social, político, económico y en especial formativo, lo constituye, el diseño e implementación del modelo de Universalización, el cual tiene como objetivo supremo la extensión de la Universidad a los distintos municipios del país, con la finalidad de irradiar cultura y saber, que son las únicas modalidades de garantizar un hombre libre y de hecho una sociedad independiente. En el presente trabajo se muestra una panorámica de la Educación Superior en Cuba, partiendo del elemento histórico hasta la contemporaneidad y en ésta, los nuevos retos impuestos por el contexto socio-político a escala mundial.

  8. Infantile intracranial aneurysm of the superior cerebellar artery.

    Science.gov (United States)

    Del Santo, Molly Ann; Cordina, Steve Mario

    2016-02-29

    Intracranial aneurysms in the pediatric population are rare. We report a case of a 3-month-old infant who presented with inconsolable crying, vomiting, and sunset eye sign. CT revealed a subarachnoid hemorrhage, with CT angiogram revealing a superior cerebellar artery aneurysm. An external ventricular drain was placed for acute management of hydrocephalus, with definitive treatment by endovascular technique with a total of six microcoils to embolize the aneurysm. Serial transcranial Dopplers revealed no subsequent vasospasm. Although aneurysms in the pediatric population are rare, once the diagnosis is established, early treatment results in better outcomes. 2016 BMJ Publishing Group Ltd.

  9. CALIDAD Y EXPERIENCIA DOCENTE EN EDUCACIÓN SUPERIOR

    Directory of Open Access Journals (Sweden)

    María Isabel Lafuente Guantes

    2010-01-01

    Full Text Available En este trabajo se considera la forma de entender la calidad en la experiencia docente en educación superior a partir de la práctica del profesorado, y en relación con las orientaciones educativas hoy al uso. Se analiza en tres trabajos: las nociones en que se basa esta experiencia, su valor en el proceso docente, qué condiciones se requieren para lograr que la creencia en la calidad alcance su efectuación.

  10. A standardized surgical technique for rat superior cervical ganglionectomy

    DEFF Research Database (Denmark)

    Savastano, Luis Emilio; Castro, Analía Elizabeth; Fitt, Marcos René

    2010-01-01

    injury. Despite having several experimental applications in the rat, a thorough description of a standardized procedure has never been published. Here, we provide a brief review of the principal features and experimental uses of the SCGx, the surgical anatomy of the neck and sympathetic cervical chain......, and a step-by-step description of how to consistently remove the superior cervical ganglia through the omohyoid muscle or the carotid triangle. Furthermore, we suggest procedures and precautions to be taken during and after surgery to optimize results and describe tools to validate surgical success. We...

  11. Superior Valley photovoltaic power processing and system controller evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Bonn, R.; Ginn, J.; Zirzow, J.; Sittler, G.

    1995-11-01

    Sandia National Laboratories, sponsored by the US Department of Energy`s Office of Energy Management, conducts the photovoltaic balance-of-system program. Under this program, Sandia supports the Department of Defense Strategic Environmental Research Development Plan, SERDP, which is advancing the use of photovoltaics in operational DoD facilities. This report details the acceptance testing of the first of these photovoltaic hybrid systems: the Superior Valley photovoltaic-diesel hybrid system. This is the first of several photovoltaic installations for the Department of Defense. The system hardware tested at Sandia included an inverter, maximum power trackers, and a system controller.

  12. Study on evaluation system of high & new technology superior enterprises

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    With the globalization of economy and science & technology, high & new technology enterprises have become the point of Chinese economic growth and the important basis for constructing innovative country. By analyzing the characteristics of high & new technology superior enterprises and the influential factors, the evaluation index and method based on Grey Relation Analysis are designed. Some high & new technology enterprises in Heilongjiang province are evaluated and application tactics of evaluation system are proposed. This study provides scientific method and basis for government to obtain development state about high & new technology enterprises and design planning and policies of high & new technology industry.

  13. Viabilidade de uma rede social no ensino superior do Turismo

    OpenAIRE

    Salgado, Manuel; Faria, César

    2010-01-01

    O artigo estuda a organização da rede de instituições presentes no ensino superior do Turismo em Portugal e o interesse de criar uma rede social neste âmbito. No seguimento apresenta-se o projecto Observatório Nacional de Educação em Turismo, que constituirá uma plataforma tecnológica de trabalho para esta comunidade académica, com vista à sua organização e funcionamento eficiente em rede, partilhando conhecimento e experiências relevantes a nível nacional e regional, gerando valor acrescenta...

  14. El lenguaje y la educación superior

    Directory of Open Access Journals (Sweden)

    Juan Carlos Vergara Silva

    2001-07-01

    Full Text Available En este artículo se plantea el análisis de algunos retos que genera la relación entre el lenguaje y la educación superior en una sociedad digital; así mismo, se establece cómo los usuarios de las nuevas tecnologías exigen al docente universitario un manejo efectivo de los lenguajes hipertextuales a fin de superar el esquema de "transmisor de información", heredado de los modelos tradicionales de educación.

  15. El volcanismo del Terciario superior del sur de Mendoza

    Directory of Open Access Journals (Sweden)

    F. E. Nullo

    2002-06-01

    Full Text Available Se describe por primera vez la petrografía y geoquímica de unidades volcánicas terciarias del sur de la provincia de Mendoza. Se analizan la nomenclatura estratigráfica y sus edades, estableciéndose una secuencia de eventos magmáticos ocurridos durante el Neógeno, comenzando con la evolución de un retro-arco, seguido por un arco magmático más joven. Se intenta respetar la nomenclatura estratigráfica existente, sin embargo, la definición de unidades se ha realizado sobre la base de las edades radimétricas y sus edades de cristalización, más sobre sus características petrográficas. La actividad magmática se extiende desde el Oligoceno superior al Mioceno superior, correspondiendo a el Ciclo Eruptivo Molle y el Ciclo Eruptivo Huincán, y comenzó con un episodio magmático basáltico inicial (CEM. Esta actividad se generó en la corteza inferior dominada por la concentración de gabros, dioritas y rocas híbridas (granulitas máficas. Debido a un engrosamiento de la corteza como consecuencia de la actividad tectónica durante Mioceno superior o por el estancamiento de magmas o por la combinación de ambos procesos, la formación de granulitas granatíferas resultó un producto distintivo de la corteza inferior. Con el desarrollo del arco magmático (CEH en el Mioceno superior, los magmas ascendieron desde la fuente mantélica, encontrándose con una corteza inferior granatífera, perdiendo capacidad de ascenso por falta de contraste de densidades, produciéndose una fusión extendida, la homogeinización y el ascenso, en equilibrio con la corteza baja, proceso que caracteriza el volcanismo de un arco magmático.

  16. Polyarteritis nodosa in superior mesenteric artery : a case report

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Young Lan; Choi, Chul Soon; Kim, Ho Chul; Bae, Sang Hoon; Lee, Eil Seong; Nam, Eun Sook [Hallym Univ., Choonchun (Korea, Republic of). Coll. of Medicine

    1998-03-01

    Polyarteritis nodosa (PAN) is a multisystem disease characterized by necrotizing vasculitis of small and medium-sized arteries, and in 50 % of all cases there is gastrointestinal involvement. We describe a patient with PAN involving the gastrointestinal tract. A small bowel series showed nodular fold thickening, submucosal filling defects, shallow ulcerations, segmental luminal narrowing, and decreased peristalsis at the duodenum, jejunum, and ileum; superior mesenteric arteriography showed hypervascularity and microaneurysm. Segmental resection of the small bowel indicated the presence of PAN. (author). 10 refs.,3 figs.

  17. Superior dislocation of the patella: a case report

    Directory of Open Access Journals (Sweden)

    Garcia-Balletbo Montserrat

    2009-07-01

    Full Text Available Abstract Background Superior dislocation of the patella is an uncommon condition that mainly occurs in knees with a high patella and medial femorotibial degenerative arthritis. There are no previous reports of this condition occurring in association with tibial valgus osteotomy. Case report: We report the case of a patient in whom vertical dislocation recurred twice at 4 months after tibial valgus osteotomy. To avert additional recurrence or new dislocations, the patient was treated surgically to remove the existing osteophytes. Conclusions: An arthroscopic approach was decided because of the lower associated morbidity and good results with this technique compared to open surgery.

  18. Enlarged transacromial superior approach with reverse shoulder arthroplasty for fractures

    Directory of Open Access Journals (Sweden)

    Alexandre Poignard

    2013-10-01

    Full Text Available The authors describe a step-by-step technique for reverse total shoulder arthroplasty using arthrotomy via the enlarged transacromial superior approach. This technique seems ideal for reinsertion of the tuberosities and to ensure adequate postoperative tensional balance of the infraspinatus and the subscapularis, which is critical for the rotator cuffs to function properly and to achieve optimal arthroplasty stability. Reviewing these different steps helps understanding each rotator cuff individual component's contribution to achieve optimal arthroplasty stability and external rotation with a reverse shoulder arthroplasty.

  19. CHALLENGES IN ENGINEERINGS DEGREE BASED ON SUPERIOR EDUCATION COMPETITIONS

    Directory of Open Access Journals (Sweden)

    Maricela Sánchez López

    2011-04-01

    Full Text Available The Nineties are characterized by the sprouting of projects of curricular reform that respond to certain educative demands. UNESCO, indicates that the new generations will have to be prepared with new competitions and new knowledge reason why the education superior faces the formation based on the competitions and the relevance of the curricula that constantly are adapted to the present and future needs of the society for which it requires one better joint with the problems of the society and the enterprise world.

  20. Concomitant Persistent Left Superior Vena Cava and Horseshoe Kidney

    Directory of Open Access Journals (Sweden)

    Faraz Jaffer

    2015-01-01

    Full Text Available Persistent left superior vena cava (PLSVC and horseshoe kidney (HSK are common congenital abnormalities; however presence of both in the same person is extremely rare. A patient with hepatitis C cirrhosis awaiting transplant presented with worsening liver dysfunction, diagnosed with acute renal failure secondary to hepatorenal syndrome, and required X-ray fluoroscopy guided tunneled venous catheter placement for hemodialysis. Review of imaging studies demonstrated coexistence of PLSVC and HSK. PLSVC in adulthood is usually incidental with the most common drainage pattern being without physiologic dysfunction. Isolated horseshoe kidney is still the most common of renal fusion anomalies; however etiology of coexistent PLSVC remains unknown.

  1. Double innervations to the superior belly of omohyoid

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    Rao TR

    2008-12-01

    Full Text Available Awareness in the variations of infrahyoid muscles is useful guide for both in studies of human anatomy and in clinical practice today. The use of muscular flaps as a reconstructive tool requires a thorough anatomical knowledge of its blood supply and innervations. These muscles vary considerably in the extent of their development. The omohyoid is the most frequently absent muscle of this group. We present a rare case of double nerve supply to the superior belly of omohyoid, which was found during our routine anatomical dissection on the right side of the neck of a 55-year-old male cadaver.

  2. [Clinical manifestation and surgical treatment of superior lumbar disc herniation].

    Science.gov (United States)

    Klishin, D N; Dreval', O N; Gorozhanin, A V

    2011-01-01

    On the basis of analysis of presentation and surgical treatment of 103 patients with lumbar disc herniation the authors performed comparative assessment of symptoms and therapeutic techniques in patients with higher and lower lumbar disc disease. Short-term and long-term results were evaluated using visual analogue scale and Oswestry disability index (ODI). Statistically significant differences in dynamics of pain and ODI were not present. In spite of differences in clinical presentation, the results of surgical treatment in both groups were similar. They depended on severity of preoperative neurological deficit regardless of level of lesion. Specific features of surgical procedure in superior lumbar disk herniation are described.

  3. I problemi di matematica della Scuola Normale Superiore di Pisa

    CERN Document Server

    Profeti, Alessandro

    1998-01-01

    Nasce come aggiornamento del volume precedente ("I problemi di Matematica della Scuola Normale", 1984) e raccoglie gli esercizi di matematica assegnati all'esame di ammissione alla Scuola Normale Superiore di Pisa dal 1985 al 1997, con la loro risoluzione. Per rendere più efficace lo scopo didattico viene anche presentata una scelta di problemi relativi al periodo precedente (1905-1984). Il libro si rivolge a studenti e docenti della Scuola Secondaria, e si chiude con un Glossario in cui vengono richiamati i termini usati.

  4. Complication of Right Subclavian Vein Catheterization: Superior Vena Cava Perforation

    OpenAIRE

    ÇELİK, B.; KOCAMANOĞLU, S.; BÜYÜKKARABACAK, Y. B.; SARIHASAN, E.

    2013-01-01

    Central venous catheterization is an invasive approach which is routinely used in thoracic surgery operations. Pneumothorax and hemothorax are among the most frequent complications. Vena cava superior (VCS) perforation (0.5 %) is very rarely observed. A 65-year-old male patient was admitted to the hospital with the complaint of cough. With the examinations performed, he was diagnosed with epidermoid lung cancer located in the right lower lobe of the lung (Stage IB, T2N0M0). To prepare the pat...

  5. Retos y perspectivas de la Educación Superior

    Directory of Open Access Journals (Sweden)

    Carlos Tünnermann Bemheim

    2000-12-01

    Full Text Available Las características de una educación superior capaz de hacer frente a las demandas de los próximos años, - los primeros de un nuevo siglo y un nuevo milenio, durante los cuales asistimos, además, a un cambio de épocas - , son analizados en este trabajo. Para ello, el autor se apoya en los aportes de diferentes documentos internacionales sobre este asunto, en las reflexiones del ex Director General de la UNESCO, Profesor Federico Mayor Zaragoza y, sobre todo, en su propia dilatadísima experiencia en el ámbito universitario.

  6. Superior Mesenteric Artery Dissection after Extracorporeal Shockwave Lithotripsy

    Directory of Open Access Journals (Sweden)

    Christos Bakoyiannis

    2012-01-01

    Full Text Available The use of shockwave lithotripsy is currently the mainstay of treatment in renal calculosis. Several complications including vessel injuries have been implied to extracorporeal shockwave lithotripsy. We report an isolated dissection of the superior mesenteric artery in a 60-year-old male presenting with abdominal pain which occurred three days after extracorporeal shockwave lithotripsy. The patient was treated conservatively and the abdominal pain subsided 24 hours later. The patient's history, the course of his disease, and the timing may suggest a correlation between the dissection and the ESWL.

  7. Abordagem do marketing de relacionamento no ensino superior

    OpenAIRE

    2005-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção. A presente dissertação é um estudo exploratório sobre a viabilidade de implementação de uma abordagem de marketing de relacionamento nas universidades privadas e comunitárias do Estado de Santa Catarina, Brasil. Realiza uma análise do atual cenário competitivo do ensino superior brasileiro e catarinense por meio de levantamentos oficiais, com o objetivo ...

  8. Superiority, competition, and opportunism in the evolutionary radiation of dinosaurs.

    Science.gov (United States)

    Brusatte, Stephen L; Benton, Michael J; Ruta, Marcello; Lloyd, Graeme T

    2008-09-12

    The rise and diversification of the dinosaurs in the Late Triassic, from 230 to 200 million years ago, is a classic example of an evolutionary radiation with supposed competitive replacement. A comparison of evolutionary rates and morphological disparity of basal dinosaurs and their chief "competitors," the crurotarsan archosaurs, shows that dinosaurs exhibited lower disparity and an indistinguishable rate of character evolution. The radiation of Triassic archosaurs as a whole is characterized by declining evolutionary rates and increasing disparity, suggesting a decoupling of character evolution from body plan variety. The results strongly suggest that historical contingency, rather than prolonged competition or general "superiority," was the primary factor in the rise of dinosaurs.

  9. An unusual cause of intraoperative acute superior vena cava syndrome

    Directory of Open Access Journals (Sweden)

    Adam W Amundson

    2013-01-01

    Full Text Available Acute intraoperative superior vena cava (SVC syndrome is an exceedingly rare complication in the cardiac surgical population. We describe the case of a 71-year-old female undergoing multi-vessel coronary artery bypass grafting who developed acute intraoperative SVC syndrome following internal thoracic artery harvest retractor placement. Her symptoms included severe plethora, facial engorgement and scleral edema, which was associated with hypotension and severe elevation of central venous pressure. Transesophageal echocardiography was crucial in the diagnosis, management, and optimal retractor placement ensuring adequate SVC flow. Potential causes of intraoperative SVC syndrome are reviewed as well as management options.

  10. Proceso de la educación superior en Colombia

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    Jorge Eliécer Ruíz

    1968-01-01

    Full Text Available Que las instituciones presentan características congruentes con la realidad que las sustenta, no es un hallazgo tortuoso ni una verdad cuyo descubrimiento debamos a los esfuerzos dialécticos del marxismo. Desgraciadamente al no contar con una historia confiable de nuestra sociedad y de nuestras instituciones, hemos de apelar a testimonios aislados que nos permitan inferir lo que ha sido la educación, y principalmente la educación superior, dentro del proceso evolutivo de nuestro pueblo.

  11. Continuous nanoscale carbon fibers with superior mechanical strength.

    Science.gov (United States)

    Liu, Jie; Yue, Zhongren; Fong, Hao

    2009-03-01

    Continuous nanoscale carbon fibers can be developed by stabilization and carbonization of highly aligned and extensively stretched electrospun polyacrylonitrile copolymer nanofiber precursor under optimal tension. These carbon fibers, with diameters of tens of nanometers, are expected to possess a superior mechanical strength that is unlikely to be achieved through conventional approaches. This is because i) the innovative precursor, with a fiber diameter approximately 100 times smaller than that of conventional counterparts, possesses an extremely high degree of macromolecular orientation and a significantly reduced amount of structural imperfections, and ii) the ultrasmall fiber diameter also effectively prevents the formation of structural inhomogeneity, particularly sheath/core structures during stabilization and carbonization.

  12. Do institutional investors have superior stock selection ability in China?

    Institute of Scientific and Technical Information of China (English)

    Yihong; Deng; Yongxing; Xu

    2011-01-01

    This paper uses unique data on the shareholdings of both institutional and individual investors to directly investigate whether institutional investors have better stock selection ability than individual investors in China.Controlling for other factors,we find that institutional investors increase(decrease)their shareholdings in stocks that subsequently exhibit positive(negative)short-and long-term cumulative abnormal returns.In contrast individual investors decrease(increase)their shareholdings in stocks that subsequently exhibit positive(negative)short-and long-term cumulative abnormal returns.These findings indicate that institutional investors have superior stock selection ability in China.

  13. Cognitive abilities and superior decision making under risk

    Directory of Open Access Journals (Sweden)

    Edward T. Cokely

    2009-02-01

    Full Text Available Individual differences in cognitive abilities and skills can predict normatively superior and logically consistent judgments and decisions. The current experiment investigates the processes that mediate individual differences in risky choices. We assessed working memory span, numeracy, and cognitive impulsivity and conducted a protocol analysis to trace variations in conscious deliberative processes. People higher in cognitive abilities made more choices consistent with expected values; however, expected-value choices rarely resulted from expected-value calculations. Instead, the cognitive ability and choice relationship was mediated by the number of simple considerations made during decision making --- e.g., transforming probabilities and considering the relative size of gains. Results imply that, even in simple lotteries, superior risky decisions associated with cognitive abilities and controlled cognition can reflect metacognitive dynamics and elaborative heuristic search processes, rather than normative calculations. Modes of cognitive control (e.g., dual process dynamics and implications for process models of risky decision-making (e.g., priority heuristic are discussed.

  14. Treatment of Superior Lobe Central Lung Cancer with Lung Replantation

    Directory of Open Access Journals (Sweden)

    Yulun YANG

    2010-11-01

    Full Text Available Background and objective Patients suffering from lung cancer often have poor quality of life after pneumonectomy. It has clinical significances to preserve maximum lobes of the “healthy” lung. The aim of this study is to report the applications of lung replantation in treatment of superior lobe central lung cancer. Methods Three lung cancer cases were included and analysed. The bronchus and margin of lower lung lobe were encroached by cancer. Pulmonary artery was invaded and surrounded by metastatic lymph node. Complete pneumonectomy, antegrade perfusion and retroperfusion with low-potassium dextran (LPD solution in vitro were performed. The retainable lower pulmonary lobe was selected from the isolated lung and superior pulmonary vein was replaced with inferior pulmonary veins. The bronchus and pulmonary artery were inosculated by turns. Results The operative cumulative time ranged from 220 min to 250 min. The isolated time of lobus inferior pulmonary ranged from 120 min to 150 min. The chest tube was pulled out after chest X-ray confirmed the reimplant lung full re-expansion. The patients were followed up for 4 months to 8 months and accomplished adjuvant chemotherapy for 3 or 4 periodicities. The patients had a sound quality of life. Conclusion Lung replantation removing the extensive tumor tissue and retaining the maximum pulmonary normal tissue is an useful method for treatment of lung cancer.

  15. Notas sobre o CNE e a qualidade do ensino superior

    Directory of Open Access Journals (Sweden)

    Weber Silke

    2002-01-01

    Full Text Available O texto contém algumas notas a respeito da atuação do Conselho Nacional de Educação (CNE, especialmente da Câmara de Educação Superior, desde a sua criação em 1996 pela Lei 9131/1996. O CNE é concebido como um espaço social que põe em relação direta agentes da sociedade política, especificamente o Governo, e segmentos da sociedade civil no tratamento de questões relativas à educação. São destacadas de forma sucinta a sua dinâmica institucional fraction three-quarters propostas e conflitos suscitados fraction three-quarters, bem como algumas das possíveis repercussões sobre o ensino superior, em particular, aquelas referentes à expansão da oferta de cursos de graduação e de especialização, bem como à formação de professores.

  16. A standardized surgical technique for rat superior cervical ganglionectomy.

    Science.gov (United States)

    Savastano, Luis Emilio; Castro, Analía Elizabeth; Fitt, Marcos René; Rath, Martin Fredensborg; Romeo, Horacio Eduardo; Muñoz, Estela Maris

    2010-09-30

    Superior cervical ganglionectomy (SCGx) is a valuable microsurgical model to study the role of the sympathetic nervous system in a vast array of physiological and pathological processes, including homeostatic regulation, circadian biology and the dynamics of neuronal dysfunction and recovery after injury. Despite having several experimental applications in the rat, a thorough description of a standardized procedure has never been published. Here, we provide a brief review of the principal features and experimental uses of the SCGx, the surgical anatomy of the neck and sympathetic cervical chain, and a step-by-step description of how to consistently remove the superior cervical ganglia through the omohyoid muscle or the carotid triangle. Furthermore, we suggest procedures and precautions to be taken during and after surgery to optimize results and describe tools to validate surgical success. We expect that the following standardized and optimized protocol will allow researchers to organize knowledge into a cohesive framework in those areas where the SCGx is applied. Copyright 2010 Elsevier B.V. All rights reserved.

  17. SUPERIOR MESENTERIC AND PORTAL VEIN THROMBOSIS WITH HYPERHOMOCYSTEINEMIA

    Directory of Open Access Journals (Sweden)

    Tumma

    2015-02-01

    Full Text Available Superior mesenteric venous thrombosis is a rare & life threatening condition. We report a case of 18 years old boy presented to emergency department with pain abdomen, fever, Melena for almost week duration. Bowel sounds were absent since two days. With a preoperative diagnosis of peritonitis Patient was taken up for emergency laparotomy. Resection of gangrenous small bowel and end to end anastomosis was done. Intra operatively thrombus in SMV was found. Coagulation profile was normal except for elevated homocystine levels. Early postoperative period was stormy. Patient was started on LMV Heparin from day - 1. Pregangrenous changes were seen in contrast CT abdomen on Day - 4. We managed conservatively with anticoagulation therapy in the postoperative period. Pregangrenous changes disappeared with conservative management. Patient was shifted to oral warfarin and discharged on 3 rd week. Follow up Doppler USG abdomen revealed a portal vein of normal size & caliber with no evidence of thrombus. On postoperative follow up for one year, patient is doing well. Hyperhomocycteinemia is an independent predisposing factor to superior mesenteric venous thrombus.

  18. Visual sensitivity of deepwater fishes in Lake Superior.

    Directory of Open Access Journals (Sweden)

    Kelly A Harrington

    Full Text Available The predator-prey interactions in the offshore food web of Lake Superior have been well documented, but the sensory systems mediating these interactions remain unknown. The deepwater sculpin, (Myoxocephalus thompsoni, siscowet (Salvelinus namaycush siscowet, and kiyi (Coregonus kiyi inhabit low light level environments. To investigate the potential role of vision in predator-prey interactions, electroretinography was used to determine visual sensitivity for each species. Spectral sensitivity curves revealed peak sensitivity at 525 nm for each species which closely corresponds to the prevalent downwelling light spectrum at depth. To determine if sufficient light was available to mediate predator-prey interactions, visual sensitivity was correlated with the intensity of downwelling light in Lake Superior to construct visual depth profiles for each species. Sufficient daytime irradiance exists for visual interactions to approximately 325 m for siscowet and kiyi and 355 m for the deepwater sculpin during summer months. Under full moon conditions, sufficient irradiance exists to elicit ERG response to light available at approximately 30 m for the siscowet and kiyi and 45 m for the deepwater sculpin. Visual interactions are therefore possible at the depths and times when these organisms overlap in the water column indicating that vision may play a far greater role at depth in deep freshwater lakes than had been previously documented.

  19. Superior cross-species reference genes: a blueberry case study.

    Directory of Open Access Journals (Sweden)

    Jose V Die

    Full Text Available The advent of affordable Next Generation Sequencing technologies has had major impact on studies of many crop species, where access to genomic technologies and genome-scale data sets has been extremely limited until now. The recent development of genomic resources in blueberry will enable the application of high throughput gene expression approaches that should relatively quickly increase our understanding of blueberry physiology. These studies, however, require a highly accurate and robust workflow and make necessary the identification of reference genes with high expression stability for correct target gene normalization. To create a set of superior reference genes for blueberry expression analyses, we mined a publicly available transcriptome data set from blueberry for orthologs to a set of Arabidopsis genes that showed the most stable expression in a developmental series. In total, the expression stability of 13 putative reference genes was evaluated by qPCR and a set of new references with high stability values across a developmental series in fruits and floral buds of blueberry were identified. We also demonstrated the need to use at least two, preferably three, reference genes to avoid inconsistencies in results, even when superior reference genes are used. The new references identified here provide a valuable resource for accurate normalization of gene expression in Vaccinium spp. and may be useful for other members of the Ericaceae family as well.

  20. Designing functionally graded materials with superior load-bearing properties.

    Science.gov (United States)

    Zhang, Yu; Sun, Ming-Jie; Zhang, Denzil

    2012-03-01

    Ceramic prostheses often fail from fracture and wear. We hypothesize that these failures may be substantially mitigated by an appropriate grading of elastic modulus at the ceramic surface. In this study, we elucidate the effect of elastic modulus profile on the flexural damage resistance of functionally graded materials (FGMs), providing theoretical guidelines for designing FGMs with superior load-bearing property. The Young's modulus of the graded structure is assumed to vary in a power-law relation with a scaling exponent n; this is in accordance with experimental observations from our laboratory and elsewhere. Based on the theory for bending of graded beams, we examine the effect of n value and bulk-to-surface modulus ratio (E(b)/E(s)) on stress distribution through the graded layer. Theory predicts that a low exponent (0.15graded materials with various n values and E(b)/E(s) ratios can be fabricated by infiltrating alumina and zirconia with a low-modulus glass. Flexural tests show that graded alumina and zirconia with suitable values of these parameters exhibit superior load-bearing capacity, 20-50% higher than their homogeneous counterparts. Improving load-bearing capacity of ceramic materials could have broad impacts on biomedical, civil, structural, and an array of other engineering applications.

  1. Origen de la Escuela Normal Superior de México

    Directory of Open Access Journals (Sweden)

    Patricia Ducoing

    2004-01-01

    Full Text Available En este texto se pretende analizar el origen universitario de la Escuela Normal Superior de México, en el marco del período denominado “porfiriato”, el cual, pese a haberse convertido en una dictadura, enarboló los principios de la ideología liberal, los que unidos al pensamiento positivista cotidiano, posibilitaron el desarrollo económico y social y particularmente, educativo, a través de la creación de instituciones y de programas que potenciaron la conformación de un discurso pedagógico moderno. La Escuela Normal Superior nace, en el seno de la Universidad Nacional, como expresión de un proyecto político-cultural que integra las aspiraciones de la época en materia educativa: la organización y homogeneización de un sistema de formación de profesores que contribuyera a garantizar la ruptura con los postulados y símbolos del régimen colonial, los cuales habrían de ser suplantados por otros: la unidad, la cientificidad, el pragmatismo y la secularidad -entre otros-.

  2. Adjuvant chemotherapy compliance is not superior after thoracoscopic lobectomy

    DEFF Research Database (Denmark)

    Licht, Peter B; Schytte, Tine; Jakobsen, Erik

    2014-01-01

    BACKGROUND: It is generally assumed that patient compliance with adjuvant chemotherapy is superior after video-assisted thoracoscopic surgery compared with open lobectomy for non-small cell lung cancer (NSCLC). The level of evidence for this assumption, however, is limited to single-institution, ......BACKGROUND: It is generally assumed that patient compliance with adjuvant chemotherapy is superior after video-assisted thoracoscopic surgery compared with open lobectomy for non-small cell lung cancer (NSCLC). The level of evidence for this assumption, however, is limited to single...... histopathology. A clinical oncologist, who was blinded to the surgical approach, reviewed all medical oncology charts for types of adjuvant chemotherapy, reasons for not initiating or stopping treatment, number of cycles delivered, and time interval from surgery to initial chemotherapy. RESULTS: During a 6-year...... adjuvant chemotherapy and 121 (38.7%) completed all four cycles. Ordinal logistic regression revealed that chemotherapy compliance (none, partial, and full chemotherapy) was significantly reduced by the patient's age (p

  3. Fish community change in Lake Superior, 1970-2000

    Science.gov (United States)

    Bronte, Charles R.; Ebener, Mark P.; Schreiner, Donald R.; DeVault, David S.; Petzold, Michael M.; Jensen, Douglas A.; Richards, Carl; Lozano, Steven J.

    2003-01-01

    Changes in Lake Superior's fish community are reviewed from 1970 to 2000. Lake trout (Salvelinus namaycush) and lake whitefish (Coregonus clupeaformis) stocks have increased substantially and may be approaching ancestral states. Lake herring (Coregonus artedi) have also recovered, but under sporadic recruitment. Contaminant levels have declined and are in equilibrium with inputs, but toxaphene levels are higher than in all other Great Lakes. Sea lamprey (Petromyzon marinus) control, harvest limits, and stocking fostered recoveries of lake trout and allowed establishment of small nonnative salmonine populations. Natural reproduction supports most salmonine populations, therefore further stocking is not required. Nonnative salmonines will likely remain minor components of the fish community. Forage biomass has shifted from exotic rainbow smelt (Osmerus mordax) to native species, and high predation may prevent their recovery. Introductions of exotics have increased and threaten the recovering fish community. Agencies have little influence on the abundance of forage fish or the major predator, siscowet lake trout, and must now focus on habitat protection and enhancement in nearshore areas and prevent additional species introductions to further restoration. Persistence of Lake Superior's native deepwater species is in contrast to other Great Lakes where restoration will be difficult in the absence of these ecologically important fishes.

  4. Medical image of the week: persistent left superior vena cava

    Directory of Open Access Journals (Sweden)

    Hammode E

    2014-10-01

    Full Text Available No abstract available. Article truncated after 150 words. A 19 year old man with acute lymphocytic leukemia was admitted to the ICU with septic shock. Due to areas of cellulitis on the right side of the chest and neck and femoral venous thrombi, a left subclavian central access was attempted. The chest x-ray obtained after line placement is shown below (Figure 1. Blood gas done from the line was consistent with venous blood and venous tranduction was seen. A CT of the chest (Figure 2 confirmed the diagnosis of persistent left superior vena cava (PLSVC. A persistent left superior vena cava is the most common congenital thoracic venous anomaly, seen in 0.3-0.5% of the population (1. Incidence is increased in patients with congenital heart disease to 5%. In most patients a right sided SVC is also present; hence the term SVC duplication has also been used. Embryologically a PLSVC is formed when the left anterior cardinal vein is ...

  5. Phlegmonous gastritis secondary to superior mesenteric artery syndrome

    Directory of Open Access Journals (Sweden)

    Kosuke Nomura

    2015-12-01

    Full Text Available We herein report a case of phlegmonous gastritis secondary to superior mesenteric artery syndrome. An 80-year-old woman visited the hospital emergency department with the chief complaints of epigastric pain and vomiting. She was hospitalized urgently following the diagnosis of superior mesenteric artery syndrome based on abdominal computed tomography findings. Conservative therapy was not effective, and phlegmonous gastritis was diagnosed based on the findings of upper gastrointestinal endoscopy and biopsy performed on the 12th day of the disease. Undernutrition and reduced physical activity were observed on hospital admission, and proactive nutritional therapy with enteral nutrition was started. An upper gastrointestinal series, performed approximately 1 month later, confirmed the persistence of strictures and impaired gastric emptying. Because conservative therapy was unlikely to improve oral food intake, open total gastrectomy was performed on the 94th day of the disease. Examination of surgically resected specimens revealed marked inflammation and fibrosis, especially in the body of the stomach. Following a good postoperative recovery, the patient was able to commence oral intake and left our hospital on foot approximately 1 month after surgery.

  6. Personality assessment with children of superior intelligence: divergence versus psychopathology.

    Science.gov (United States)

    Gallucci, N T

    1989-01-01

    The perceptual and cognitive functioning of children with intelligence quotients greater than 135 was examined with the Rorschach Inkblot Test. A criterion measure, the Child Behavior Checklist, was also administered so as to determine whether deviations for Rorschach variables from age-appropriate norms indicated the presence of psychopathology or were evidence of nonentrenched, novel, or creative styles of encoding and processing information. Rorschach variables indicative of intellectual sophistication, nonentrenched thinking or inaccurate reality perception, and cognitive slippage were reliably elevated for this sample versus norms. Results for the Child Behavior Checklist demonstrated that the incidence of psychopathology in the intellectually superior and average samples were comparable. There was a lack of covariance between Rorschach makers of inaccurate reality perception, cognitive slippages, and schizophrenia, and the sum of behavior problems on the Child Behavior Checklist. Results for the Rorschach and Child Behavior Checklist variables were comparable for children with intelligence quotients greater than 150 versus between 136 and 140. It was concluded that the intellectually superior children did process the Rorschach stimuli in a manner that was nonentrenched and reliably different from norms, but that these differences should not routinely be considered as indications of psychopathology.

  7. de tomada de decisão em cursos superiores

    Directory of Open Access Journals (Sweden)

    Ricardo Shitsuka

    2005-01-01

    Full Text Available As empresas têm obtido vantagens competitivas com o uso extensivo dos sistemas de informação. Em sua forma atual, esses sistemas se compõem, principalmente, de tecnologia de informação, organização e pessoas. No presente trabalho, estuda-se o uso, no ensino superior, de ferramentas de planilhas eletrônicas como parte dos sistemas de informação, destinados ao apoio computacional à tomada de decisão. Conta-se, para isso, com a experiência dos autores, como docentes em cursos de bacharelado e tecnologia, nas disciplinas que utilizam esse recurso, e de pesquisas que apontam a tendência para o uso dessas ferramentas. Sugere-se, para os interessados em ingressar na área empresarial, o aprendizado dessas importantes ferramentas computacionais, a exemplo do que vem ocorrendo no ensino superior, com a utilização crescente de planilhas eletrônicas no apoio ao processo de tomada de decisões.

  8. La educación superior en Cundinamarca

    Directory of Open Access Journals (Sweden)

    Raúl Palomar Áviles

    2015-04-01

    Full Text Available RESUMEN El artículo parte de un análisis de la ubicación geográfica y espacial del departamento de Cundinamarca, destacando la marcada centralización que tiene Bogotá en todos los órdenes, dada su cercanía. Destaca que, a pesar de la metropolización que tiene a ejercer Bogotá, el departamento cuenta con cuatro ciudades intermedias y alternas con la posibilidad de convertirse en polos de desarrollo regional autónomos. Presenta una descripción de la Educación superior en Cundinamarca, tanto en  la modalidad presencial como en la modalidad  a distancia. Concluye que la cobertura de este nivel educativo es casi nula precisamente por la dependencia que existen 900 cupos en 2 instituciones de Educación Superior, ubicadas en 4 ciudades, para atender  una población de 6.800 bachilleres que egresan anualmente.

  9. Superior Semicircular Canal Dehiscence Syndrome – Diagnosis and Surgical Management

    Science.gov (United States)

    Palma Diaz, Marite; Cisneros Lesser, Juan Carlos; Vega Alarcón, Alfredo

    2017-01-01

    Introduction Superior semicircular canal dehiscence syndrome was described by Minor et al in 1998. It is a troublesome syndrome that results in vertigo and oscillopsia induced by loud sounds or changes in the pressure of the external auditory canal or middle ear. Patients may present with autophony, hyperacusis, pulsatile tinnitus and hearing loss. When symptoms are mild, they are usually managed conservatively, but surgical intervention may be needed for patients with debilitating symptoms. Objective The aim of this manuscript is to review the different surgical techniques used to repair the superior semicircular canal dehiscence. Data Sources PubMed and Ovid-SP databases. Data Synthesis The different approaches are described and discussed, as well as their limitations. We also review the advantages and disadvantages of the plugging, capping and resurfacing techniques to repair the dehiscence. Conclusions Each of the surgical approaches has advantages and disadvantages. The middle fossa approach gives a better view of the dehiscence, but comes with a higher morbidity than the transmastoid approach. Endoscopic assistance may be advantageous during the middle cranial fossa approach for better visualization. The plugging and capping techniques are associated with higher success rates than resurfacing, with no added risk of hearing loss. PMID:28382131

  10. Superior cross-species reference genes: a blueberry case study.

    Science.gov (United States)

    Die, Jose V; Rowland, Lisa J

    2013-01-01

    The advent of affordable Next Generation Sequencing technologies has had major impact on studies of many crop species, where access to genomic technologies and genome-scale data sets has been extremely limited until now. The recent development of genomic resources in blueberry will enable the application of high throughput gene expression approaches that should relatively quickly increase our understanding of blueberry physiology. These studies, however, require a highly accurate and robust workflow and make necessary the identification of reference genes with high expression stability for correct target gene normalization. To create a set of superior reference genes for blueberry expression analyses, we mined a publicly available transcriptome data set from blueberry for orthologs to a set of Arabidopsis genes that showed the most stable expression in a developmental series. In total, the expression stability of 13 putative reference genes was evaluated by qPCR and a set of new references with high stability values across a developmental series in fruits and floral buds of blueberry were identified. We also demonstrated the need to use at least two, preferably three, reference genes to avoid inconsistencies in results, even when superior reference genes are used. The new references identified here provide a valuable resource for accurate normalization of gene expression in Vaccinium spp. and may be useful for other members of the Ericaceae family as well.

  11. The Word Superiority Effect in central and peripheral vision

    DEFF Research Database (Denmark)

    Sand, Katrine; Habekost, Thomas; Petersen, Anders

    2016-01-01

    The Word Superiority Effect (WSE) is a well-known phenomenon in reading research, where words are reported more accurately than single letters or non-words. We report two experiments that investigate the WSE in the central and peripheral visual field, as well as laterality differences in the perc......The Word Superiority Effect (WSE) is a well-known phenomenon in reading research, where words are reported more accurately than single letters or non-words. We report two experiments that investigate the WSE in the central and peripheral visual field, as well as laterality differences...... in the perception of words and letters, using methods based on the Theory of Visual Attention. The results show a WSE in the central visual field, reflected in mean scores, perception thresholds, and processing speed, whereas the effect is eliminated or reversed in the periphery. This may be caused by crowding......, which prevents lexical analysis of a word in the periphery. We conclude that perception of words and letters differs according to location in the visual field. Linking our results to previous studies of crowding effects in patients with reading impairments, we hypothesize that similar mechanisms may...

  12. Mnemonic Training Reshapes Brain Networks to Support Superior Memory.

    Science.gov (United States)

    Dresler, Martin; Shirer, William R; Konrad, Boris N; Müller, Nils C J; Wagner, Isabella C; Fernández, Guillén; Czisch, Michael; Greicius, Michael D

    2017-03-08

    Memory skills strongly differ across the general population; however, little is known about the brain characteristics supporting superior memory performance. Here we assess functional brain network organization of 23 of the world's most successful memory athletes and matched controls with fMRI during both task-free resting state baseline and active memory encoding. We demonstrate that, in a group of naive controls, functional connectivity changes induced by 6 weeks of mnemonic training were correlated with the network organization that distinguishes athletes from controls. During rest, this effect was mainly driven by connections between rather than within the visual, medial temporal lobe and default mode networks, whereas during task it was driven by connectivity within these networks. Similarity with memory athlete connectivity patterns predicted memory improvements up to 4 months after training. In conclusion, mnemonic training drives distributed rather than regional changes, reorganizing the brain's functional network organization to enable superior memory performance. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Sustained attention is associated with right superior longitudinal fasciculus and superior parietal white matter microstructure in children.

    Science.gov (United States)

    Klarborg, Brith; Skak Madsen, Kathrine; Vestergaard, Martin; Skimminge, Arnold; Jernigan, Terry L; Baaré, William F C

    2013-12-01

    Sustained attention develops during childhood and has been linked to the right fronto-parietal cortices in functional imaging studies; however, less is known about its relation to white matter (WM) characteristics. Here we investigated whether the microstructure of the WM underlying and connecting the right fronto-parietal cortices was associated with sustained attention performance in a group of 76 typically developing children aged 7-13 years. Sustained attention was assessed using a rapid visual information processing paradigm. The two behavioral measures of interest were the sensitivity index d' and the coefficient of variation in reaction times (RTCV ). Diffusion-weighted imaging was performed. Mean fractional anisotropy (FA) was extracted from the WM underlying right dorsolateral prefrontal (DLPFC) and parietal cortex (PC), and the right superior longitudinal fasciculus (SLF), as well as equivalent anatomical regions-of-interest (ROIs) in the left hemisphere and mean global WM FA. When analyzed collectively, right hemisphere ROIs FA was significantly associated with d' independently of age. Follow-up analyses revealed that only FA of right SLF and the superior part of the right PC contributed significantly to this association. RTCV was significantly associated with right superior PC FA, but not with right SLF FA. Observed associations remained significant after controlling for FA of equivalent left hemisphere ROIs or global mean FA. In conclusion, better sustained attention performance was associated with higher FA of WM in regions connecting right frontal and parietal cortices. Further studies are needed to clarify to which extent these associations are driven by maturational processes, stable characteristics and/or experience.

  14. The Anatomic Course of the First Jejunal Branch of the Superior Mesenteric Vein in Relation to the Superior Mesenteric Artery

    Directory of Open Access Journals (Sweden)

    Pavlos Papavasiliou

    2012-01-01

    Full Text Available Introduction. The purpose of this study is to determine the anatomic course of the first jejunal branch of the superior mesenteric vein (SMV in relation to the superior mesenteric artery (SMA. Methods. Three hundred consecutive contrast-enhanced computed tomography (CT scans were reviewed by a surgical oncologist with confirmation of findings by a radiologist. Results. The overall incidence of a first jejunal branch coursing anterior to the SMA was 41%. There was no correlation between patient gender and position of the jejunal branch. In addition, there was no correlation between size of the first jejunal branch and its location in relation to the SMA. The IMV drained into the SMV in 27% of the patients. The IMV drained into the SMV-portal vein confluence in 17% of patients and inserted into the splenic vein in 54%. An anterior coursing first jejunal branch statistically correlated with an IMV that drained into the SMV-portal vein confluence (=0.009. Conclusion. The first jejunal branch of the SMV has a highly variable course in relation to the SMA and has a higher incidence of an anterior location in this population than previously reported.

  15. Surgical Results in Unilateral Superior Oblique Muscle Palsy

    Directory of Open Access Journals (Sweden)

    Aylin Tenlik

    2014-08-01

    Full Text Available Objectives: To evaluate the surgical treatments and results of the patients with superior oblique muscle palsy (SOMP. Materials and Methods: Clinical charts of the patients with unilateral SOMP who were operated in our clinic between 1999 and 2009 were evaluated retrospectively. Patients’ demographics, preoperative signs, surgical procedure, complications, and final results were recorded. Results: Thirty-seven patients were included in the study, [21 (59% male, 15 (41% female]. The mean age was 20.6 years at the time of operation. The mean time interval between diagnosis and operation was 7.3 years. Postoperative follow-up period was 2.04 (ranging 1-10 years. Diplopia was determined in seven (18.9% patients, and abnormal head position in 36 (97.3% patients. Only inferior oblique tenotomy with distal muscle resection was performed in 25 patients. In addition, five patients had recession of the contralateral inferior rectus muscle and two patients had recession of the ipsilateral superior rectus muscle additional to inferior oblique tenotomy. Abnormal head position was completely improved in all of the patients postoperatively. The preoperative average score of the inferior oblique muscle (IOM overaction was +3.3±0.8, and postoperative overaction was found in only two patients (+1.5. There was statistically significant difference between the two periods (p<0.001. The average score of the superior oblique muscle hypofunction was -2.18 preoperatively, and in only three patients, the score was found -1.0 postoperatively. Difference between the two periods was statistically significant (p<0.001. While the preoperative average vertical deviation was 22 PD in primary position, none of the patients had hyperdeviation postoperatively. Diplopia was resolved in all seven affected patients postoperatively. Contralateral IOM hyperfunction was the most common complication (13.5%. Adherence syndrome was seen in none of the patients. Conclusion: It was found

  16. Quadrilobed superior gluteal artery perforator flap for sacrococcygeal defects

    Institute of Scientific and Technical Information of China (English)

    HAI Heng-lin; SHEN Chuan-an; CHAI Jia-ke; LI Hua-tao; YU Yong-ming; LI Da-wei

    2013-01-01

    Background Perforator flaps are used extensively in repairing soft tissue defects.Superior gluteal artery perforatorflaps are used for repairing sacral defects,but the tension required for direct closure of the donor area after harvesting ofrelatively large flaps carries a risk of postoperative dehiscence.This research was to investigate a modified superiorgluteal artery perforator flap for repairing sacrococcygeal soft tissue defects.Methods From June 2003 to April 2010,we used our newly designed superior gluteal artery perforator flap for repair of sacrococcygeal soft tissue defects in 10 patients (study group).The wound and donor areas were measured,and the flaps were designed accordingly.Wound healing was assessed over a follow-up period of 6-38 months.From January 1998 to February 2003,twelve patients with sacrococcygeal pressure sores were treated with traditional methods,VY advancement flaps or oblong flaps,as control group.Results After debridement,the soft tissue defects ranged from 12 cm × 10 cm to 26 cm × 22 cm (mean 16.3 cm x 13.5cm).Four patients were treated using right-sided flaps ranging from 15 cm × 11 cm to 25 cm × 20 cm (mean 18.2 cm × 14cm).Four patients were treated using left-sided flaps,and two were treated using both right-and left-sided flaps.Suction drains were removed on postoperative Days 3-21 (mean 5.9) and sutures were removed on postoperative Days 12-14.Each flap included 1-2 perforators for each of the donor and recipient sites.Donor sites were closed directly.All flaps survived.In eight patients,the wounds healed after single-stage surgery.After further debridement,the wounds of the remaining two patients were considered healed on postoperative Days 26 and 33,respectively.The rate of first intention in the study group (80%,8/10) significantly increased than that of control group ((25%,3/12),X2=4.583,P=-0.032).Follow-up examinations found that the flaps had a soft texture without ulceration.In the two patients without

  17. Tissue preserving total hip arthroplasty using superior capsulotomy.

    Science.gov (United States)

    Capuano, N; Del Buono, A; Maffulli, N

    2015-08-01

    The goals of a tissue-preserving minimally invasive approach to the hip are to allow early short-term recovery, achieve hip joint stability, minimize muscle strength loss from surgery, spare the peri-articular soft tissues, and allow unrestricted motion in the long term. Hip arthroplasty in patients with no pre-existing hardware, with a sufficient space between the acetabular rim and greater trochanter; management of subcapital femoral fractures in older patients. Protrusio acetabuli. Joint stiffness. This is the main concern when undertaking the superior capsulotomy. Stiffness may result from bone causes, including ankylosis, large osteophytes, bone bridges etc., extra-articular retraction of surrounding soft tissues with capsular contracture of both ligaments and muscles, or a combination of bony and soft tissues causes, resulting in limited adduction. Indeed, maximal adduction is necessary to increase the distance between the apex of the greater trochanter and the superior acetabular edge. In the approach described in the present article, the real limitation is the impossibility to introduce a straight stem through the trochanteric fossa without weakening the trochantericarea. If adduction is restricted, excessive lateralization of the femoral stem would result in postoperative pain and discomfort, especially as we advocate immediate full weight bearing. Even though patients fare better when the trochanteric area is intact, many types of stem such as the GTS (Biomet), or stem Microplasty (Biomet) or even stem Parva (Adler Ortho) may pressurize the internal bone of the trochanteric structures. Therefore, these stems may be implanted in maximal hip adduction. This is the case in coxa profunda or coxa vara, which require more invasive and destabilizing surgical approaches. Lateral position, 5-8 cm incision from the tip of the greater trochanter, identification and transaction of piriformis tendon. Anterior mobilization of the gluteus minimus and exposure of the

  18. Coastal geology and recent origins for Sand Point, Lake Superior

    Science.gov (United States)

    Fisher, Timothy G.; Krantz, David E.; Castaneda, Mario R.; Loope, Walter L.; Jol, Harry M.; Goble, Ronald J.; Higley, Melinda C.; DeWald, Samantha; Hansen, Paul

    2014-01-01

    Sand Point is a small cuspate foreland located along the southeastern shore of Lake Superior within Pictured Rocks National Lakeshore near Munising, Michigan. Park managers’ concerns for the integrity of historic buildings at the northern periphery of the point during the rising lake levels in the mid-1980s greatly elevated the priority of research into the geomorphic history and age of Sand Point. To pursue this priority, we recovered sediment cores from four ponds on Sand Point, assessed subsurface stratigraphy onshore and offshore using geophysical techniques, and interpreted the chronology of events using radiocarbon and luminescence dating. Sand Point formed at the southwest edge of a subaqueous platform whose base is probably constructed of glacial diamicton and outwash. During the post-glacial Nipissing Transgression, the base was mantled with sand derived from erosion of adjacent sandstone cliffs. An aerial photograph time sequence, 1939–present, shows that the periphery of the platform has evolved considerably during historical time, infl uenced by transport of sediment into adjacent South Bay. Shallow seismic refl ections suggest slump blocks along the leading edge of the platform. Light detection and ranging (LiDAR) and shallow seismic refl ections to the northwest of the platform reveal large sand waves within a deep (12 m) channel produced by currents fl owing episodically to the northeast into Lake Superior. Ground-penetrating radar profi les show transport and deposition of sand across the upper surface of the platform. Basal radiocarbon dates from ponds between subaerial beach ridges range in age from 540 to 910 cal yr B.P., suggesting that Sand Point became emergent during the last ~1000 years, upon the separation of Lake Superior from Lakes Huron and Michigan. However, optically stimulated luminescence (OSL) ages from the beach ridges were two to three times as old as the radiocarbon ages, implying that emergence of Sand Point may have begun

  19. Recurrent cerebral venous infarcts and superior vena cava obstruction: case report

    Energy Technology Data Exchange (ETDEWEB)

    Bozzao, A. [Department of Radiology, University of Rome ``Tor Vergata``, Rome (Italy)]|[Istituto di Radiologia, Ospedale S. Eugenio, Piazzale dell`Umanesimo 10 I-00144 Roma (Italy); Gallucci, M. [Department of Neuroradiology, University of L`Aquila, L`Aquila (Italy); Marsili, L. [Department of Neuroradiology, University of L`Aquila, L`Aquila (Italy); Cerone, G. [Department of Neurology, Collemaggio Hospital, L`Aquila (Italy)

    1997-06-01

    We report a patient with repeated venous infarcts in the occipital lobe and occlusion of the superior vena cava. The pathogenetic relationships between the superior vena cava occlusion and the brain infarcts are discussed. High pressure in the superior venous territory and incomplete patency of the transverse sinus are probably responsible for the venous infarcts. (orig.). With 4 figs.

  20. Superiority of Bessel function over Zernicke polynomial as base function for radial expansion in tomographic reconstruction

    Indian Academy of Sciences (India)

    A K Chattopadhyay; C V S Rao

    2003-07-01

    Here we describe the superiority of Bessel function as base function for radial expansion over Zernicke polynomial in the tomographic reconstruction technique. The causes for the superiority have been described in detail. The superiority has been shown both with simulated data for Kadomtsev’s model for saw-tooth oscillation and real experimental x-ray data from W7-AS Stellarator.

  1. File list: Pol.Neu.05.AllAg.Superior_Cervical_Ganglion [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  1. File list: Oth.Neu.05.AllAg.Superior_Cervical_Ganglion [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  3. File list: His.Neu.05.AllAg.Superior_Cervical_Ganglion [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  4. Superior Sagittal Sinus Thrombosis Complicating Typhoid Fever in a Teenager

    Directory of Open Access Journals (Sweden)

    P. O. Okunola

    2012-01-01

    Full Text Available Cerebral venous sinus (sinovenous thrombosis (CSVT is a rare life-threatening disorder in childhood that is often misdiagnosed. CSVT encompasses cavernous sinus thrombosis, lateral sinus thrombosis, and superior sagittal sinus thrombosis (SSST. We present an adolescent girl who was well until two weeks earlier when she had a throbbing frontal headache and fever with chills; she later had dyspnoea, jaundice, melena stool, multiple seizures, nuchal rigidity, and monoparesis of the right lower limb a day before admission. Urine test for Salmonella typhi Vi antigen was positive, and Widal reaction was significant. Serial cranial computerized tomography scans revealed an expanding hypodense lesion in the parafalcine region consistent with SSST or a parasagittal abscess. Inadvertent left parietal limited craniectomy confirmed SSST. She recovered completely with subsequent conservative management. Beyond neuropsychiatric complications of Typhoid fever, CSVT should be highly considered when focal neurologic deficits are present.

  5. Superior orbital fissure syndrome in herpes zoster ophthalmicus.

    LENUS (Irish Health Repository)

    Kirwan, R P

    2012-02-01

    AIM: To report a case of superior orbital fissure syndrome (SOFS) in a patient with herpes zoster ophthalmicus (HZO). MATERIALS AND METHODS: A case report. RESULTS: A 71-year-old male with HZO presented acutely to accident and emergency complaining of right vision loss, double vision and drowsiness. The right visual acuity was counting fingers. There was no relative afferent pupillary defect. He had interstitial keratitis, ptosis, proptosis and total ophthalmoplaegia. The signs indicated HZO complicated by SOFS. Brain imaging and lumbar puncture confirmed the diagnosis of varicella zoster encephalitis. Systemic acyclovir and prednisolone led to recovery of visual acuity and ocular motility in addition to resolution of his proptosis and ptosis. CONCLUSION: SOFS is a rare complication of herpes zoster infection. With the appropriate treatment and follow-up, patients may be reassured that recovery of their visual acuity and ocular motility will occur.

  6. No superior adaptations to carbohydrate periodization in elite endurance athletes

    DEFF Research Database (Denmark)

    Gejl, Kasper Degn; Thams, Line; Hansen, Mette

    2017-01-01

    content (18 ± 5%), CS activity (11 ± 5%) and pACC (38 ± 19%) (Ptraining had no superior effects on performance and muscle...... endurance training, while matched and randomized into two groups training with (Low) or without (High) carbohydrate (CHO) manipulation three days a week. The CHO manipulation days consisted of a 1-hr high intensity bike session in the morning, recovery for 7 hrs while consuming isocaloric diets containing...... either high CHO (414±2.4 g) or low CHO (79.5±1.0 g), and a 2-hr moderate bike session in the afternoon with or without CHO. VO2max, maximal fat oxidation and power output during a 30-min time trial (TT) were determined before and after the training period. The TT was undertaken after 90 mins...

  7. Superior optical nonlinearity of an exceptional fluorescent stilbene dye

    Energy Technology Data Exchange (ETDEWEB)

    He, Tingchao [College of Physics Science and Technology, Shenzhen University, Shenzhen 518060 (China); Division of Physics and Applied Physics, Centre for Disruptive Photonic Technologies (CDPT), School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore); Sreejith, Sivaramapanicker; Zhao, Yanli [Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore); Gao, Yang; Grimsdale, Andrew C. [School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore 639798 (Singapore); Lin, Xiaodong, E-mail: linxd@szu.edu.cn, E-mail: hdsun@ntu.edu.sg [College of Physics Science and Technology, Shenzhen University, Shenzhen 518060 (China); Sun, Handong, E-mail: linxd@szu.edu.cn, E-mail: hdsun@ntu.edu.sg [Division of Physics and Applied Physics, Centre for Disruptive Photonic Technologies (CDPT), School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore)

    2015-03-16

    Strong multiphoton absorption and harmonic generation in organic fluorescent chromophores are, respectively, significant in many fields of research. However, most of fluorescent chromophores fall short of the full potential due to the absence of the combination of such different nonlinear upconversion behaviors. Here, we demonstrate that an exceptional fluorescent stilbene dye could exhibit efficient two- and three-photon absorption under the excitation of femtosecond pulses in solution phase. Benefiting from its biocompatibility and strong excited state absorption behavior, in vitro two-photon bioimaging and superior optical limiting have been exploited, respectively. Simultaneously, the chromophore could generate efficient three-photon excited fluorescence and third-harmonic generation (THG) when dispersed into PMMA film, circumventing the limitations of classical fluorescent chromophores. Such chromophore may find application in the production of coherent light sources of higher photon energy. Moreover, the combination of three-photon excited fluorescence and THG can be used in tandem to provide complementary information in biomedical studies.

  8. Superior optical nonlinearity of an exceptional fluorescent stilbene dye

    Science.gov (United States)

    He, Tingchao; Sreejith, Sivaramapanicker; Gao, Yang; Grimsdale, Andrew C.; Zhao, Yanli; Lin, Xiaodong; Sun, Handong

    2015-03-01

    Strong multiphoton absorption and harmonic generation in organic fluorescent chromophores are, respectively, significant in many fields of research. However, most of fluorescent chromophores fall short of the full potential due to the absence of the combination of such different nonlinear upconversion behaviors. Here, we demonstrate that an exceptional fluorescent stilbene dye could exhibit efficient two- and three-photon absorption under the excitation of femtosecond pulses in solution phase. Benefiting from its biocompatibility and strong excited state absorption behavior, in vitro two-photon bioimaging and superior optical limiting have been exploited, respectively. Simultaneously, the chromophore could generate efficient three-photon excited fluorescence and third-harmonic generation (THG) when dispersed into PMMA film, circumventing the limitations of classical fluorescent chromophores. Such chromophore may find application in the production of coherent light sources of higher photon energy. Moreover, the combination of three-photon excited fluorescence and THG can be used in tandem to provide complementary information in biomedical studies.

  9. superior o atractivo artilugio estético?

    Directory of Open Access Journals (Sweden)

    Miguel Angel Munive Villanueva

    2007-01-01

    Full Text Available En este ensayo se presenta un análisis de la acreditación bajo la idea de que es el mejor instrumento para fortalecer la mejora de la calidad de la educación superior, lo que da lugar a la reflexión sobre la manera en que se logran sus objetivos y resultados. Este preámbulo es la pauta que sirve para abordar la acreditación no como la simple conquista o adjudicación de una constancia de un órgano o instancia acreditadora, poniendo de realce que la efectividad y trascendencia de la acreditación, y particularmente de la evaluación, radica en su integración formal a los procesos de planeación de las tareas académicas y de apoyo de las entidades académicas.

  10. Phonetic Feature Encoding in Human Superior Temporal Gyrus

    Science.gov (United States)

    Mesgarani, Nima; Cheung, Connie; Johnson, Keith; Chang, Edward F.

    2015-01-01

    During speech perception, linguistic elements such as consonants and vowels are extracted from a complex acoustic speech signal. The superior temporal gyrus (STG) participates in high-order auditory processing of speech, but how it encodes phonetic information is poorly understood. We used high-density direct cortical surface recordings in humans while they listened to natural, continuous speech to reveal the STG representation of the entire English phonetic inventory. At single electrodes, we found response selectivity to distinct phonetic features. Encoding of acoustic properties was mediated by a distributed population response. Phonetic features could be directly related to tuning for spectrotemporal acoustic cues, some of which were encoded in a nonlinear fashion or by integration of multiple cues. These findings demonstrate the acoustic-phonetic representation of speech in human STG. PMID:24482117

  11. ENSINO SUPERIOR E OS PARADIGMAS DA POLÍTICA NEOLIBERAL

    OpenAIRE

    Hebert de Melo

    2010-01-01

    Este artigo científico procurou investigar o processo de adaptação da Universidade Brasileira aos novos paradigmas impostos pelas políticas neoliberais. A análise se faz a partir de breve histórico do liberalismo e de suas imbricações no ensino. Apontando também a relativização da suposta democratização e modernização do ensino pelas novas perspectivas impostas pelo mercado. São levantadas também questões como autonomia universitária e legitimação da instituição de ensino superior....

  12. Superhydrophobic paper with superior stability against deformations and humidity

    Science.gov (United States)

    Wang, Nan; Xiong, Dangsheng; Pan, Sai; Deng, Yaling; Shi, Yan; Wang, Kun

    2016-12-01

    Superhydrophobic coatings on paper were achieved by means of incorporating micro-nano hierarchical topography, where the water droplet was repelled and rested in a spherical shape. A silica sol, which was prepared using tetraethylorthosilicate (TEOS) as precursor and trimethylethoxysilane (TMES) as co-precursor, was poured on the paper to form a superhydrophobic surface. The coating was fluorine-free, environmentally friend, and could be easily fabricated on different kinds of papers. Besides, the transmittance of prepared coating reached up to 92% in visible light range, and the words on treated paper showed a good visualization. Moreover, the treated paper showed superior mechanical durability against 100 times of deformation, remarkable stability towards both the acidic and basic solutions. The treated paper could withstand 70 cycles of water condensation test (from 60 °C, 90% relative humidity to 10 °C) without losing superhydrophobicity, suggesting a long-term protection for paper.

  13. Firm-specific information, analysts’ superiority and investment value

    Institute of Scientific and Technical Information of China (English)

    Lu; Li; Erjia; Yang; Tusheng; Xiao

    2014-01-01

    Using a sample of Chinese security analysts’recommendations from 2005 to2010,we examine the source of analysts’superiority and the investment value of their recommendations.Using a calendar-time portfolio approach,we find that,on average,analysts’recommendations are valuable and that analysts are better at analyzing and transferring firm-specific information than market-wide or industry-level information.In addition,we show that the investment value of recommendations increases as firm-specific information becomes more important in stock pricing.Our empirical results are useful in guiding investors and helping brokerage houses to evaluate the output of research departments.

  14. Phonetic feature encoding in human superior temporal gyrus.

    Science.gov (United States)

    Mesgarani, Nima; Cheung, Connie; Johnson, Keith; Chang, Edward F

    2014-02-28

    During speech perception, linguistic elements such as consonants and vowels are extracted from a complex acoustic speech signal. The superior temporal gyrus (STG) participates in high-order auditory processing of speech, but how it encodes phonetic information is poorly understood. We used high-density direct cortical surface recordings in humans while they listened to natural, continuous speech to reveal the STG representation of the entire English phonetic inventory. At single electrodes, we found response selectivity to distinct phonetic features. Encoding of acoustic properties was mediated by a distributed population response. Phonetic features could be directly related to tuning for spectrotemporal acoustic cues, some of which were encoded in a nonlinear fashion or by integration of multiple cues. These findings demonstrate the acoustic-phonetic representation of speech in human STG.

  15. [Human interaction, social cognition, and the superior temporal sulcus].

    Science.gov (United States)

    Brunelle, Francis; Saitovitch, Anna; Boddaert, Nathalie; Grevent, David; Cambier, Jean; Lelord, Gilbert; Samson, Yves; Zilbovicius, Monica

    2013-01-01

    Human beings are social animals. This ability to live together is ensured by cognitive functions, the neuroanatomical bases of which are starting to be unraveled by MRI-based studies. The regions and network engaged in this process are known as the "social brain ". The core of this network is the superior temporal sulcus (STS), which integrates sensory and emotional inputs. Modeling studies of healthy volunteers have shown the role of the STS.in recognizing others as biological beings, as well as facial and eye-gaze recognition, intentionality and emotions. This cognitive capacity has been described as the "theory of mind ". Pathological models such as autism, in which the main clinical abnormality is altered social abilities and communication, have confirmed the role of the STS in the social brain. Conceptualisation of this empathic capacity has been described as "meta cognition ", which forms the basis of human social organizationand culture.

  16. Mediastinal seminoma presenting with superior vena cava syndrome.

    Science.gov (United States)

    Wanous, Amanda; McPhail, Ian R; Quevedo, J Fernando; Sandhu, Nicole P

    2017-06-08

    We present a rare cause of superior vena cava syndrome (SVC) in a previously healthy male aged 31 years. Malignancy was suspected due to unintentional weight loss and childhood exposure to radioactive fallout from a nuclear facility accident. A very large anterior mediastinal mass was identified and demonstrated to be an extragonadal seminoma. Extragonadal germ cell tumours are rare tumours with a high potential for cardiovascular, pulmonary and vascular sequelae. Studies have documented an increased risk of developing seminoma in patients with radioactive exposure. Chemotherapy was initiated, during which the patient experienced progressive and new symptoms, found to be due to extensive thromboembolic disease, which responded well to anticoagulation. Seventy-two months after completing chemotherapy, without need for surgical management, he remains free of the disease. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  17. Voice range in superior laryngeal nerve paresis and paralysis.

    Science.gov (United States)

    Eckley, C A; Sataloff, R T; Hawkshaw, M; Spiegel, J R; Mandel, S

    1998-09-01

    Evaluation of Physiologic Frequency Range (PFR) and Musical Frequency Range (MRP) of Phonation was performed on 56 adults (singers and nonsingers) presenting with superior laryngeal nerve (SLN) paresis or paralysis confirmed by laryngeal electromyography. The most common etiology was neuritis (69.7%), followed by iatrogenic and unknown causes,each accounting for 10.2% of cases, and finally trauma (8.9%). Both female and male singers with SLN paresis or paralysis had significantly higher PFR and MPR than nonsingers. Female classical singers presented PFR and MPR of up to 10 semitones (ST) higher than nonclassical singers and nonsingers. The lowest PFR and musical ranges were found in patients with SLN paresis associated with recurrent laryngeal nerve paresis or paralysis. The authors suggest that voice range measurement is a useful parameter for analyzing the effects of SLN paresis or paralysis on voice and that it may also assist in measuring outcome following voice therapy.

  18. Ensino superior, para quê? Higher education, what for?

    Directory of Open Access Journals (Sweden)

    Henry Giroux

    2010-05-01

    Full Text Available O texto propõe retomar a universidade democrática como referência ética, em face dos desafios do mundo globalizado. Discute a situação atual das universidades, caracterizada como uma crise mundial no Ensino Superior, tendo como referência as IES dos Estados Unidos da América e do Canadá. São destacados três aspectos nessa questão-problema: 1- as consequências do movimento de globalização, que atinge todas as esferas da vida humana, entre elas a educação, e demandam do Ensino Superior o exercício da função de educar as gerações futuras para enfrentar os desafios de uma democracia global, evitando adotar a prática da indução dos professores e alunos à instrumentalização e ao imediatismo, subvalorizando o conhecimento crítico. 2- a retomada pelas universidades de seus objetivos de conhecimento e autonomia, posicionando-se contra a instrumentalização, a mercantilização e a militarização, essa última, como monitoramento de diferentes sujeitos sociais, e do Estado, exercidos sobre as IES. Para isso, propõe a colaboração inclusiva como uma das principais formas de divulgação da universidade e da importância da liberdade e da autonomia da Instituição Superior em suas decisões e ações. 3- a universidade acessível a todos que, além de possibilitar o desenvolvimento de uma educação crítica e de uma cultura intelectual verdadeira, adota metodologias prazerosas, estimulantes e capacitadoras, e valoriza os professores extinguindo os "contratos alternativos de trabalho" que têm contribuído para o empobrecimento da qualidade do Ensino Superior.The text proposes to reinstitute the democratic university as an ethic reference, given the challenges of the globalized world. It discusses the universities' current situation, which is characterized as a global crisis in higher education, taking as reference American and Canadian higher education institutions. Three aspects of such characterization are highlighted: 1

  19. Retinal Origin of Direction Selectivity in the Superior Colliculus

    Science.gov (United States)

    Shi, Xuefeng; Barchini, Jad; Ledesma, Hector Acaron; Koren, David; Jin, Yanjiao; Liu, Xiaorong; Wei, Wei; Cang, Jianhua

    2017-01-01

    Detecting visual features in the environment such as motion direction is crucial for survival. The circuit mechanisms that give rise to direction selectivity in a major visual center, the superior colliculus (SC), are entirely unknown. Here, we optogenetically isolate the retinal inputs that individual direction-selective SC neurons receive and find that they are already selective as a result of precisely converging inputs from similarly-tuned retinal ganglion cells. The direction selective retinal input is linearly amplified by the intracollicular circuits without changing its preferred direction or level of selectivity. Finally, using 2-photon calcium imaging, we show that SC direction selectivity is dramatically reduced in transgenic mice that have decreased retinal selectivity. Together, our studies demonstrate a retinal origin of direction selectivity in the SC, and reveal a central visual deficit as a consequence of altered feature selectivity in the retina. PMID:28192394

  20. Retinal origin of direction selectivity in the superior colliculus.

    Science.gov (United States)

    Shi, Xuefeng; Barchini, Jad; Ledesma, Hector Acaron; Koren, David; Jin, Yanjiao; Liu, Xiaorong; Wei, Wei; Cang, Jianhua

    2017-04-01

    Detecting visual features in the environment, such as motion direction, is crucial for survival. The circuit mechanisms that give rise to direction selectivity in a major visual center, the superior colliculus (SC), are entirely unknown. We optogenetically isolate the retinal inputs that individual direction-selective SC neurons receive and find that they are already selective as a result of precisely converging inputs from similarly tuned retinal ganglion cells. The direction-selective retinal input is linearly amplified by intracollicular circuits without changing its preferred direction or level of selectivity. Finally, using two-photon calcium imaging, we show that SC direction selectivity is dramatically reduced in transgenic mice that have decreased retinal selectivity. Together, our studies demonstrate a retinal origin of direction selectivity in the SC and reveal a central visual deficit as a consequence of altered feature selectivity in the retina.

  1. ENSINO SUPERIOR E OS PARADIGMAS DA POLÍTICA NEOLIBERAL

    Directory of Open Access Journals (Sweden)

    Hebert de Melo

    2010-07-01

    Full Text Available Este artigo científico procurou investigar o processo de adaptação da Universidade Brasileira aos novos paradigmas impostos pelas políticas neoliberais. A análise se faz a partir de breve histórico do liberalismo e de suas imbricações no ensino. Apontando também a relativização da suposta democratização e modernização do ensino pelas novas perspectivas impostas pelo mercado. São levantadas também questões como autonomia universitária e legitimação da instituição de ensino superior.

  2. Category superiority effects and the processing of auditory images.

    Science.gov (United States)

    Sharps, M J; Pollitt, B K

    1998-04-01

    Music and information appear to be processed by means of the phonological loop, as opposed to the visuospatial sketchpad, in working memory. Is this also true of memory for nonverbal, nonmusical auditory images, such as the characteristic sounds made by objects? In the present study, university students were presented with equivalent verbal stimuli, nonsemantic auditory stimuli, or pictorial stimuli, by category or in random order. Significant category superiority effects (CSEs) were obtained for both verbal and auditory stimuli, but not for pictorial stimuli, consistent with the expectation of phonological loop processing. However, absolute levels of recall for auditory stimuli were significantly higher than for verbal stimuli and did not differ from the levels observed for pictures, suggesting a somewhat intermediate character of processing for nonverbal, nonmusical auditory information.

  3. Catheter-Induced Thrombosis of the Superior Vena Cava

    Directory of Open Access Journals (Sweden)

    Elio Venturini

    2012-01-01

    Full Text Available There has been an increase in the use of central venous catheters (CVCs in clinical practice. One of the most dangerous complications associated with their use is symptomatic or asymptomatic thrombosis (T, sometimes associated with superior vena cava (SVC syndrome, resulting from impaired venous drainage. The right heart clots can induce an increased risk of mortality due the potential pulmonary embolism (PE. We report a case of asymptomatic 83-year-old woman in whom the thrombosis was detected after an echocardiogram. Echocardiography demonstrated a cardiac mass, and the T was confirmed by (magnetic resonance imaging MRI. The clinical scenario, a high index of suspicion and routine use of echocardiogram in patients with CVC, can lead to a correct diagnosis, preventing dangerous complications.

  4. Chronic dissection of the superior mesenteric artery: case report

    Energy Technology Data Exchange (ETDEWEB)

    Common, A.A.; Pressacco, J. [Univ. of Toronto, St. Michael' s Hospital, Dept. of Medical Imaging, Toronto, Ontario (Canada)

    1999-02-01

    Acute dissection of the thoracic aorta is a well-recognized, often fatal condition that frequently extends to involve the abdominal aorta and iliac vessels. The ostia of the renal and mesenteric vessels may be compromised, and the resulting visceral ischemia may necessitate surgical intervention. However, visceral perfusion may be restored if blood flow from true to false lumen is re-established or if the false lumen is obliterated, either spontaneously or by surgical or interventional techniques. Isolated dissections of mesenteric, renal, and carotid vessels are rarely reported. These may be spontaneous, related to high blood pressure and underlying disease of the vessel wall, or caused by abdominal trauma or medical intervention, including angiographic procedures. They are usually associated with pain and other signs and symptoms of ischemia in the appropriate territory. We present a case of chronic superior mesenteric artery (SMA) dissection, an incidental angiographic finding, in an asymptomatic patient being evaluated for resection of an abdominal aortic aneurysm (AAA). (author)

  5. ESTUDIO DEL BULLYING EN EL CICLO SUPERIOR DE PRIMARIA

    Directory of Open Access Journals (Sweden)

    Rosario Ruiz Arroyo

    2015-01-01

    Full Text Available Nuestra investigación trata el fenómeno del bullying en el ciclo superior de primaria. Para llevarla a cabo, hemos elaborado un cuestionario ad hoc a partir de una revisión bibliográfica de diferentes investigaciones en las que se han utilizado varios instrumentos, pruebas, cuestionarios... Este instrumento nos ha servido para analizar diferentes temas: la percepción que tienen los niños de ciclo superior sobre el bullying, en qué escenarios del centro escolar se producen más estos comportamientos, los diferentes tipos de bullying (físico, verbal y exclusión social y cuáles se producen más a menudo y analizar las respuestas que nos dan los alumnos en función del género y del curso (5.º y 6.º. Los resultados que hemos obtenido muestran, entre otras cosas: que en los niños se da más el bullying físico, mientras que en las niñas predomina el de tipo verbal y exclusión social; que la única diferencia según el curso es que en 6.º curso se da más exclusión social que en 5.º curso; y que donde se producen más conductas de bullying es en el patio, seguido del aula cuando no se encuentra el docente. Finalmente, partiendo de los resultados obtenidos, hemos elaborado unas propuestas de actuación psicopedagógicas para mejorar la convivencia en la escuela y otros espacios educativos.

  6. en la educación superior mexicana

    Directory of Open Access Journals (Sweden)

    César Mureddu Torres

    2006-01-01

    Full Text Available El presente escrito contempla algunas nociones de relativa novedad en el marco de nuestra política nacional, incluida la política educativa de nivel superior, es el caso concreto de la expresión, ahora tan frecuente políticas públicas. Indaga en torno a los principales impulsores que dieron origen a diversas decisiones que afectaron a la comunidad académica en su quehacer cotidiano. Hace ver que en muchas ocasiones la decisión política responde a requerimientos que proceden de actividades pertenecientes a núcleos más estructurados del actuar público. Tal es el caso de la relación entre las esferas de lo político en su intersección con lo económico. El estudio hace ver también que de esta intersección han surgido la mayor parte de las decisiones que han afectado en lo público al quehacer académico, sin que las motivaciones que llevaron a ese tipo de decisiones hayan sido consensadas, develadas y transparentes, sobre todo en lo que se refiere a sus consecuencias para la mejoría o deterioro de las actividades a regular por tales políticas. Se interroga, entonces, sobre el tipo de consecuencias que han tenido para con el actuar de esta comunidad académica las políticas públicas sobre la educación superior y la respuesta está en el título de este artículo.

  7. Educación superior, movilidad social y desigualdades interdependientes

    Directory of Open Access Journals (Sweden)

    Lorenza Villa Lever

    2016-01-01

    Full Text Available En el contexto de la globalización económica, la educación superior ha redefinido los espacios institucionales para la producción del conocimiento exigiendo una mayor competitividad de las universidades, lo que ha propiciado asimetrías en su desarrollo, ya que a partir de sus respuestas, algunas han mostrado capacidad para responder a la llamada sociedad del conocimiento, mientras que otras se han concretado a dar respuesta a las necesidades precisas del mercado local. Con ese telón de fondo, en este trabajo se analizarán cuatro aspectos de estas transformaciones en América Latina: la ampliación de la matrícula de educación superior, su distribución por estrato social y género, el proceso de segmentación institucional que ha acompañado ese proceso de crecimiento, y las percepciones de los estudiantes sobre su situación, comparada a la de sus padres. Para el análisis se trabajará con dos conceptos: el de movilidad social y el de desigualdades interdependientes. Se parte del supuesto de que a medida que el nivel de bienestar de los hijos dependa del origen socioeconómico de la familia de origen, habrá mayor reducción en las libertades efectivas en la sociedad en su conjunto, y por tanto, mayores limites a las posibilidades reales de que los individuos que provienen de hogares desfavorecidos logren la vida que desean. El trabajo está organizado en tres partes: en la primera se ubica el problema de la movilidad social en América Latina; después se exponen los resultados de una investigación empírica con estudiantes universitarios en Mé- xico; y finalmente se presentan algunas conclusiones.

  8. Agenesia de cava superior associada a bloqueio atrioventricular de 3º grau Agenesis of the right superior vena cava associated with total heart block

    Directory of Open Access Journals (Sweden)

    Gustavo J. Ventura Couto

    2008-03-01

    Full Text Available A persistência de veia cava superior esquerda com ausência da veia cava superior é uma anomalia rara, principalmente quando associada a bloqueio atrioventricular de 3º grau. Relatamos o caso de uma paciente, na qual durante implante de marca-passo definitivo, para a correção de bloqueio atrioventricular total, foi detectada presença de veia cava superior esquerda com suspeição de ausência de veia cava superior, o que levou ao emprego de técnica diferenciada para fixação do eletrodo ventricular. Para confirmação da provável agenesia, foram realizados diversos exames complementares de imagem, demonstrando-se a dificuldade no diagnóstico da síndrome aqui descrita.The superior left vena cava with the absent superior vena cava is a rare abnormality, especially when associated with total heart block. We report a case of a patient in which the presence of superior left vena cava and the absence of the superior vena cava was detected during the implantation of a pacemaker for the correction of a total heart block, which led us to use a different technique for the fixation of the ventricular electrode. To confirm the supposed absence, several image exams were made showing the difficulty on the diagnosis of the described syndrome.

  9. Combined Double Sleeve Lobectomy and Superior Vena Cava Resection for Non-small Cell Lung Cancer with Persistent Left Superior Vena Cava

    Institute of Scientific and Technical Information of China (English)

    Daxing ZHU; Xiaoming QIU; Qinghua ZHOU

    2015-01-01

    A 65-year-old man with right central type of lung squamous carcinoma was admitted to our department. Bronchoscopy displayed complete obstruction of right upper lobe bronchus and inifltration of the bronchus intermedius with tumor. Chest contrast computed tomography revealed the tumor invaded right pulmonary artery, superior vena cava, and the persistant letf superior vena cava lfowed into the coronary sinus. hTe tumor was successfully removed by means of bronchial and pulmonary artery sleeve resection of the right upper and middle lobes combined with resection and reconstruction of superior vena cava (SVC) utilizing ringed polytetralfuoroethylene gratf. To the best of our knowledge, this was the ifrst report of complete resection of locally advanced lung cancer involving superior vena cava, right pulmonary artery trunk and main bronchus with persistant letf superior vena cava.

  10. Spatial determinants of multisensory integration in cat superior colliculus neurons.

    Science.gov (United States)

    Meredith, M A; Stein, B E

    1996-05-01

    1. Although a representation of multisensory space is contained in the superior colliculus, little is known about the spatial requirements of multisensory stimuli that influence the activity of neurons here. Critical to this problem is an assessment of the registry of the different receptive fields within individual multisensory neurons. The present study was initiated to determine how closely the receptive fields of individual multisensory neurons are aligned, the physiological role of that alignment, and the possible functional consequences of inducing receptive-field misalignment. 2. Individual multisensory neurons in the superior colliculus of anesthetized, paralyzed cats were studied with the use of standard extracellular recording techniques. The receptive fields of multisensory neurons were large, as reported previously, but exhibited a surprisingly high degree of spatial coincidence. The average proportion of receptive-field overlap was 86% for the population of visual-auditory neurons sampled. 3. Because of this high degree of intersensory receptive-field correspondence, combined-modality stimuli that were coincident in space tended to fall within the excitatory regions of the receptive fields involved. The result was a significantly enhanced neuronal response in 88% of the multisensory neurons studied. If stimuli were spatially disparate, so that one fell outside its receptive field, either a decreased response occurred (56%), or no intersensory effect was apparent (44%). 4. The normal alignment of the different receptive fields of a multisensory neuron could be disrupted by passively displacing the eyes, pinnae, or limbs/body. In no case was a shift in location or size observed in a neuron's other receptive field(s) to compensate for this displacement. The physiological result of receptive-field misalignment was predictable and based on the location of the stimuli relative to the new positions of their respective receptive fields. Now, for example, one

  11. Results from a geophysical investigation of Lake Superior's ring structures

    Science.gov (United States)

    Wattrus, N. J.; Gustafson, D.

    2010-12-01

    Ring shaped depressions are widely developed on the lake floor of Lake Superior. They have not been widely reported elsewhere. The rings are typically between 200 and 300 m across and up to 5 m deep. The width of the depression ranges between 10 to 30 m. They often occur in closely spaced groups or networks but can also occur as isolated features. Several mechanisms have been proposed to explain the formation of these features; they include syneresis of the fine-grained lake floor sediments, polygonal faulting and dewatering of the lake floor sediments. High resolution bathymetric surveying with a multibeam sonar has revealed that they are comprised of pockmarks arranged in irregular polygonal patterns. Sidescan sonar images of the pockmarks often exhibit increased backscatter about the pock which could be interpreted as evidence of a lag-surface. High-resolution CHIRP sub-bottom profiling across the pocks occasionally reveal chimney-like structures below the lake floor pock. This evidence suggests that the rings were produced by the expulsion of fluid from the lake floor. This appears to have been a basin-wide event. The timing, duration and origin of this are not well known. Neither is the structure of the subsurface plumbing below these features. Here we present results from a geophysical survey conducted in northwestern Lake Superior off the western coast of Isle Royale where both isolated and grouped lake floor rings are well developed. The objectives of the survey were to define the geometry of the sub-surface plumbing below the rings and to possibly gain some insight into how these systems develop. The data collected included two high-resolution pseudo-3D single-channel seismic reflection datasets, one acquired with a small airgun and a second acquired with a CHIRP profiler. Multibeam and sidescan sonar data were also acquired as part of the survey. A 9 m piston core was collected in close proximity to a ring feature. This is used to determine the physical

  12. Escuela superior de Hacienda Pública en Speyer, Alemania

    Directory of Open Access Journals (Sweden)

    Ruf, Sep

    1963-12-01

    Full Text Available The total building program connected with this School comprises the following: 1. The Higher School itself, which has an auditorium, lecture halls, main lecture hall, rooms for scientific work done by professors and their assistants, and the usual administrative offices. 2. Living quarters for the professors and students, living rooms, a club and a flat for the porter. 3. A bar and the kitchen. 4. Garage, servicing station and a bicycle shed. The Higher School is built on a single level, around a central patio-style garden, with a pond in the middle. The library, lecture halls, and working rooms are arranged to face this inner open space. The main lecture hall rises in tiers, to facilitate the view of the speaker, and its roof emerges considerably above the level of the rest of the building, as a dominant feature. The living accommodation is housed in a four storey building. The ground floor contains the club, living rooms, and the professors and porter's flats. The upper three floors are taken up with the students rooms. These are single and double rooms. This project is simply proportioned, and the volumes and planes are very clearly differentiated, to achieve a space pattern of very clearcut outline.El conjunto de instalaciones construidas comprende: — La Escuela Superior propiamente dicha, dotada de los correspondientes auditorio, clase, aula magna, salas para trabajos científicos de profesores y asistentes y la zona de administración. — Viviendas para profesores y cursillistas, salas de estar, club y vivienda del conserje. — Bar con cocina. Garaje con estación de servicio y un local para bicicletas. La Escuela Superior se desarrolla en una sola planta, en la cual, alrededor del patio-jardín—con un estanque—, se hallan la biblioteca, clase, auditorios y salas de trabajo. El aula magna tiene acceso al nivel de suelo, y presenta una disposición escalonada que facilita la visibilidad. Como elemento dominante, este cuerpo se eleva

  13. Concepto de excelencia en enseñanza superior universitaria

    Directory of Open Access Journals (Sweden)

    Eduardo García-Jiménez

    2016-07-01

    Full Text Available La idea de excelencia es consustancial a la enseñanza superior universitaria. A pesar de la diversidad bajo la que se manifiesta, la excelencia está presente en las agendas de las universidades. Los propios cuestionamientos de la capacidad de las universidades para responder al reto de proporcionar una formación avanzada a millones de estudiantes en todo el mundo o para aportar valor añadido a la sociedad y la exigencia de que desarrollen sistemas internos de garantía de la calidad y se sometan a evaluaciones externas, no son sino evidencias de la que la excelencia debería formar parte del ADN de la enseñanza superior universitaria. El concepto de excelencia en la enseñanza es un constructo multidimensional que puede definirse en términos de proceso, producto y meta. En términos de proceso, la excelencia puede definirse a partir de elementos instruccionales vinculados a los métodos de enseñanza, a la evaluación y retroalimentación, a los recursos que hacen excelentes las experiencias de aprendizaje de los estudiantes o la integración de la enseñanza y la investigación. Pero, en la definición del concepto excelencia también intervienen otros elementos menos tangibles como el compromiso académico de estudiantes y profesores o el compromiso de los programas y cursos con la libertad académica y la igualdad. En términos de producto, la excelencia se define a través de indicadores de rendimiento, de satisfacción de los grupos de interés o de responsabilidad social. Pero, en todos los casos, la excelencia es la meta a partir de la que las instituciones universitarias realizan sus planes de futuro y su propia definición de enseñanza.

  14. The superior vena cava syndrome caused by malignant disease

    Energy Technology Data Exchange (ETDEWEB)

    Eren, Suat [Department of Radiology, Faculty of Medicine, Atatuerk University, 25240 Erzurum (Turkey)]. E-mail: suateren@atauni.edu.tr; Karaman, Adem [Department of Radiology, Faculty of Medicine, Atatuerk University, 25240 Erzurum (Turkey); Okur, Adnan [Department of Radiology, Faculty of Medicine, Atatuerk University, 25240 Erzurum (Turkey)

    2006-07-15

    Objective: The superior vena cava (SVC) obstruction by malignant diseases is either by direct invasion and compression or by tumour thrombus of the SVC. Whatever is its cause, obstruction of the SVC causes elevated pressure in the veins draining into the SVC and increased or reversed blood flow through collateral vessels. Severity of the syndrome depends on the collateral vascular system development. Therefore, imaging of the collateral veins with variable location and connection is important in determining the extension and management of the disease. Our aims are to describe collateral vessels of the superior vena cava syndrome (SVCS) related with the malignant diseases and to assess the ability of multi-detector row CT with multiplanar and 3D volume rendering techniques in determining and describing collateral circulations. Materials and methods: We present CT angiography findings of seven patients with small cell carcinoma of the lung (n = 2), squamous cell carcinoma of the lung (n = 3), Hodgkin disease of the thorax (n = 1), and squamous cell carcinoma of the oesophagus (n = 1). The patients received contrast-enhanced CT scans of the chest and abdomen on a multi-detector row CT during breath holding at suspended inspiration. Results: CT images revealed the cause and level of the SVC obstruction in all patients with axial and multiplanar reconstructed images. The SVC showed total obstruction in five patients and partial obstruction in two patients. The most common experienced collateral vessels were azygos vein (6), intercostal veins (6), mediastinal veins (6), paravertebral veins (5), hemiazygos vein (5), thoracoepigastric vein (5), internal mammary vein (5), thoracoacromioclavicular venous plexus (5), and anterior chest wall veins (5). While one case showed the portal-systemic shunt, V. cordis media and sinus coronarius with phrenic veins were enlarged in two cases, and the left adrenal vein was enlarged in a patient. In one case, the azygos vein with reversed

  15. Superior flexibility of a wrinkled carbon shell under electrochemical cycling

    KAUST Repository

    Li, Qianqian

    2014-01-01

    Nanocarbon composites have been extensively employed in engineering alloy-type anodes in order to improve the poor cyclability caused by the enormous volume changes during lithium (Li+) insertion/extraction. The chemical vapor deposited wrinkled carbon shell (WCS) shows high electrical conductivity, excellent thermal stability and remarkable mechanical robustness, which help in retaining the structural integrity around the tin (Sn) anode core despite ∼250% variation in volume during repetitive lithiation and delithiation. In situ transmission electron microscopy reveals no embrittlement in the lithiated WCS, which fully recovers its original shape after severe mechanical deformation with no obvious structural change. Further analysis indicates that the capacity to accommodate large strains is closely related to the construction of the carbon shell, that is, the stacking of wrinkled few-layer graphenes. Both the pre-existing wrinkles and the few-layer thickness render the carbon shell superior flexibility and good elasticity under bending or expansion of the interior volume. Moreover, the WCS possesses fast lithium ion diffusion channels, which have lower activation barriers (∼0.1 eV) than that on a smooth graphene (∼0.3 eV). The results provide an insight into the improvement in cycle performance that can be achieved through carbon coating of anodes of lithium ion batteries. © 2014 The Royal Society of Chemistry.

  16. Funciones superiores en pacientes con accidente cerebro vascular.

    Directory of Open Access Journals (Sweden)

    Felipe Rodríguez

    2009-07-01

    Full Text Available Los estudios realizados en Chile hasta la fecha no permiten detectar de manera significativa el deterioro neuropsicológico causado por el accidente cerebro vascular (ACV y el impacto que éste tiene en el paciente a nivel de su desenvolvimiento diario y familiar. Con base a esto el objetivo de esta investigación fue elaborar un perfil de deterioro neuropsicológico de las diversas funciones cerebrales superiores causado por un ACV, en un grupo de 50 pacientes de la Unidad de Medicina Física del Hospital San José al cuál se le administró un Protocolo de Evaluación Neuropsicológica, comparándose luego con un grupo control de 50 sujetos evaluados con el mismo protocolo. Se encuentra que sobre un 20% de la población con ACV evaluada presenta deterioro en al menos uno de los ítems evaluados, siendo las funciones ejecutivas, la memoria a largo plazo y la memoria a corto plazo las áreas mayoritariamente afectada en la población evaluada.

  17. Hypothalamic germinoma masquerading as superior mesenteric artery (SMA) syndrome.

    Science.gov (United States)

    Vethakkan, Shireene R; Venugopal, Yogeswari; Tan, Alexander T B; Paramasivam, Sharmila S; Ratnasingam, Jeyakantha; Razak, Rohaya A; Alias, Azmi; Kassim, Fauziah; Choong, Karen

    2013-01-01

    To report a case of superior mesenteric artery (SMA) syndrome secondary to hypothalamic germinoma. We describe the clinical presentation, diagnostic work-up, management, and clinical course of a patient admitted with SMA syndrome who was subsequently found to have a hypothalamic germinoma. An adolescent boy was admitted to the surgical ward with progressive weight loss over a 2 year period and postprandial vomiting. He was diagnosed with SMA syndrome based on evidence of proximal duodenal dilatation, extrinsic compression of the distal duodenum, and a narrowed aortomesenteric angle (16°). Investigations performed to exclude thyrotoxicosis unexpectedly revealed secondary hypothyroidism and further evaluation demonstrated evidence of pan-hypopituitarism. Psychiatric evaluation excluded anorexia nervosa and bulimia. Magnetic resonance imaging (MRI) of the brain revealed a heterogeneously enhancing hypothalamic lesion, but a normal pituitary gland. Hormone replacement with hydrocortisone, desmopressin, testosterone, and thyroxine resulted in weight gain and resolution of gastrointestinal symptoms. A transventricular endoscopic biopsy subsequently confirmed a hypothalamic germinoma and he was referred to an oncologist. SMA syndrome secondary to severe weight loss is an uncommon cause of upper gastrointestinal obstruction. While there have been reports of poorly controlled diabetes mellitus and thyrotoxicosis manifesting as SMA syndrome, there are no published reports to date of SMA syndrome secondary to hypothalamic/pituitary disease. Management of SMA syndrome is conservative, as symptoms of intestinal obstruction resolve with weight gain following treatment of the underlying cause. Awareness of this uncommon presentation of endocrine cachexia/hypothalamic disease will prevent unnecessary laparotomies and a misdiagnosis of an eating disorder.

  18. The superior mesenteric artery syndrome in patients with spinal deformity.

    Science.gov (United States)

    Altiok, Haluk; Lubicky, John P; DeWald, Christopher J; Herman, Jean E

    2005-10-01

    A retrospective review. To determine the incidence of the superior mesenteric artery syndrome (SMAS) after surgical correction for scoliosis and if it is influenced by newer derotation/translation surgical systems. The SMAS is a known complication after surgery. Of 2939 charts reviewed, 17 patients between 1960 and 2002 matched inclusion criteria. Our incidence of the SMAS was 0.5%. Onset of symptoms was 7.2 days. Several scoliosis diagnoses were included in the study group. Instrumentation that was used included: nondistraction systems (n = 14), Harrington rod with body cast (n = 1), Luque rod with sublaminar wires (n = 1), and casted in situ posterior spinal fusion (n = 1). Before surgery, 10 of 17 patients weighed less than the 50th percentile. Mean preoperative BMI was 18.6 kg/cm/cm. Postoperative height gain averaged 3.175 cm, and weight loss at onset of symptoms averaged 4.5 kg. There were 14 patients who required nasogastric suction for an average duration of 10.2 days, 11 required hyperalimentation, and 5 concurrently received hyperalimentation with enteric feeding. The SMAS recurred in 2 patients. Postoperative weight loss appears to be more important for the development of the SMAS than asthenic body type. Newer derotation/translation corrective techniques have not eliminated the SMAS. Gastrointestinal imaging is indicated when nausea and vomiting occur 6-12 days after surgery, associated with early satiety and normal bowel sounds. Decompression and nutritional support remain the mainstays of treatment.

  19. en estudiantes de educación superior

    Directory of Open Access Journals (Sweden)

    Julio Alfonso Piña López

    2006-01-01

    Full Text Available Se condujo un estudio transversal que tuvo como objetivo evaluar la capacidad de predicción de tres variables psicológicas: conocimientos, creencias y motivos, sobre dos comportamientos relacionadas con el uso de condón en estudiantes de educación superior de ambos sexos. El análisis de varianza en función de la edad arrojó diferencias significativas en la práctica de los dos comportamientos; con la rho de Spearman se encontraron correlaciones altas y significativas entre los motivos y los dos comportamientos, mientras que un análisis de regresión evidenció el poder de predicción de la variable motivos sobre ambos comportamientos. Se destaca la necesidad de analizar el importante papel que dicha variable desempeña en el uso de condón en esa población, especialmente para prevenir la infección por VIH.

  20. Coding of multisensory temporal patterns in human superior temporal sulcus

    Directory of Open Access Journals (Sweden)

    Toemme eNoesselt

    2012-08-01

    Full Text Available Philosophers, psychologists, and neuroscientists have long been interested in how the temporal aspects of perception are represented in the brain. In the present study, we investigated the neural basis of the temporal perception of synchrony/asynchrony for audiovisual speech stimuli using functional magnetic imaging (fMRI. Subjects judged the temporal relation of (asynchronous audiovisual speech streams, and indicated any changes in their perception of the stimuli over time. Differential hemodynamic responses for synchronous versus asynchronous stimuli were observed in the multisensory superior temporal sulcus complex (mSTS-c and prefrontal cortex. Within mSTS-c we found adjacent regions expressing an enhanced BOLD-response to the different physical (asynchrony conditions. These regions were further modulated by the subjects’ perceptual state. By calculating the distances between the modulated regions within mSTS-c in single-subjects we demonstrate that the ‘auditory’ and ‘visual leading areas’ lie closer to ‘synchrony areas’ than to each other. Moreover, analysis of interregional connectivity indicates a stronger functional connection between multisensory prefrontal cortex and mSTS-c during the perception of asynchrony. Taken together, these results therefore suggest the presence of distinct sub-regions within the human STS-c for the maintenance of temporal relations for audiovisual speech stimuli plus differential functional connectivity with prefrontal regions. The respective local activity in mSTS-c is dependent both upon the physical properties of the stimuli presented and upon the subjects’ perception of (asynchrony.

  1. Of guns and snakes: testing a modern threat superiority effect.

    Science.gov (United States)

    Subra, Baptiste; Muller, Dominique; Fourgassie, Lisa; Chauvin, Alan; Alexopoulos, Theodore

    2017-02-03

    Previous studies suggest that ancient (i.e. evolutionary-based) threats capture attention because human beings possess an inborn module shaped by evolution and dedicated to their detection. An alternative account proposes that a key feature predicting whether a stimulus will capture attention is its relevance rather than its ontology (i.e. phylogenetic or ontogenetic threat). Within this framework, the present research deals with the attentional capture by threats commonly encountered in our urban environment. In two experiments, we investigate the attentional capture by modern threats (i.e. weapons). In Experiment 1, participants responded to a target preceded by a cue, which was a weapon or a non-threatening stimulus. We found a larger cuing effect (faster reaction times to valid vs. invalid trials) with weapons as compared with non-threatening cues. In Experiment 2, modern (e.g. weapons) and ancient threats (e.g. snakes) were pitted against one another as cues to determine which ones preferentially capture attention. Crucially, participants were faster to detect a target preceded by a modern as opposed to an ancient threat, providing initial evidence for a superiority of modern threat. Overall, the present findings appear more consistent with a relevance-based explanation rather than an evolutionary-based explanation of threat detection.

  2. Inflammatory responses in the rat superior colliculus after eye enucleation.

    Science.gov (United States)

    Hernandes, Marina S; Britto, Luiz R G

    2014-02-01

    Ocular enucleation induces profound morphological alterations in central visual areas. However, little is known about the response of glial cells and possible inflammatory processes in visual brain areas resulting from eye enucleation. In this study, immunoblotting and immunostaining assays revealed increased expression of astrocyte and microglia markers in the rat superior colliculus (SC) between 1 and 15 days after contralateral enucleation. A transient increase of neuronal COX-2 protein expression was also found in the SC. To evaluate the role of an anti-inflammatory drug in attenuating both COX-2 and glial cell activation, the synthetic glucocorticoid dexamethasone (DEX) was administered (1 mg/kg i.p., for 3 days) to enucleated rats. Immunoblotting data revealed that DEX treatment significantly inhibited COX-2 protein expression. Postlesion immunostaining for astrocyte and microglia markers was also significantly reduced by DEX treatment. These findings suggest that the removal of retinal ganglion cell input generates inflammatory responses in central retinorecipient structures. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. A permeabilidade social das carreiras do ensino superior

    Directory of Open Access Journals (Sweden)

    Maria Ligia de Oliveira Barbosa

    Full Text Available Este artigo propõe-se a analisar as diferenças entre cursos pertencentes a três áreas de conhecimento (ciências biológicas, exatas e humanas quanto à sua capacidade para oferecer maior igualdade de oportunidades no momento de expansão e diversificação do ensino superior brasileiro. O estudo foi realizado a partir dos microdados do Exame Nacional de Desempenho dos Estudantes (ENADE, combinando a nota geral da prova às respostas do questionário socioeconômico dos alunos, de forma a avaliar as associações entre o financiamento dos estudos de graduação e o desempenho e permanência nos diferentes cursos. Ao mesmo tempo em que os resultados confirmam as diferenças entre as áreas de conhecimento, também indicam a importância desses mecanismos de custeio das despesas para a finalização dos cursos. Verificam-se diferenças significativas em cada curso quanto ao desempenho associado a cada tipo de bolsa e de financiamento.

  4. El contexto virtual en la educación superior

    Directory of Open Access Journals (Sweden)

    Vera Quintana, Mercedes

    2015-06-01

    Full Text Available El laboratorio virtual constituye el nuevo proceso que trata de imponer sus presupuestos técnicos, organizativos y metodológicos, por tanto, la virtualización de la educación superior durante su relativa corta vida, ha sido ese nuevo paradigma educativo resultante del uso de las tecnologías de la información y las comunicaciones (TIC, como herramienta de mediación en los procesos de aprendizaje. Los espacios virtuales de aprendizaje (EVA han revolucionado los procesos de enseñanza y aprendizaje con la explotación de sus múltiples posibilidades que indudablemente ofrecen una alternativa a los modelos pedagógicos tradicionales. Nuestra modesta propuesta se inserta metodológicamente en lo que serían estas nuevas prácticas educativas con sus correspondientes estrategias para definir el nuevo modelo pedagógico en función de los entornos virtuales.

  5. Smaller superior temporal gyrus volume specificity in schizotypal personality disorder

    Science.gov (United States)

    Goldstein, Kim E.; Hazlett, Erin A.; New, Antonia S.; Haznedar, M. Mehmet; Newmark, Randall E.; Zelmanova, Yuliya; Passarelli, Vincent; Weinstein, Shauna R.; Canfield, Emily L.; Meyerson, David A.; Tang, Cheuk Y.; Buchsbaum, Monte S.; Siever, Larry J.

    2009-01-01

    Background Superior temporal gyrus (STG/BA22) volume is reduced in schizophrenia and to a milder degree in schizotypal personality disorder (SPD), representing a less severe disorder in the schizophrenia-spectrum. SPD and Borderline personality disorder (BPD) are severe personality disorders characterized by social and cognitive dysfunction. However, while SPD is characterized by social withdrawal/anhedonia, BPD is marked by hyper-reactivity to interpersonal stimuli and hyper-emotionality. This is the first morphometric study to directly compare SPD and BPD patients in temporal volume. Methods We compared three age-gender- and education-matched groups: 27 unmedicated SPD individuals with no BPD traits, 52 unmedicated BPD individuals with no SPD traits, and 45 healthy controls. We examined gray matter volume of frontal and temporal lobe Brodmann areas (BAs), and dorsal/ventral amygdala from 3T magnetic resonance imaging. Results In the STG, an auditory association area reported to be dysfunctional in SPD and BPD, the SPD patients had significantly smaller volume than healthy controls and BPD patients. No group differences were found between BPD patients and controls. Smaller BA22 volume was associated with greater symptom severity in SPD patients. Reduced STG volume may be an important endophenotype for schizophrenia-spectrum disorders. SPD is distinct from BPD in terms of STG volume abnormalities which may reflect different underlying pathophysiological mechanisms and could help discriminate between them. PMID:19473820

  6. Autologous chondrocyte implantation: superior biologic properties of hyaline cartilage repairs.

    Science.gov (United States)

    Henderson, Ian; Lavigne, Patrick; Valenzuela, Herminio; Oakes, Barry

    2007-02-01

    Information regarding the quality of autologous chondrocyte implantation repair is needed to determine whether the current autologous chondrocyte implantation surgical technology and the subsequent biologic repair processes are capable of reliably forming durable hyaline or hyaline-like cartilage in vivo. We report and analyze the properties and qualities of autologous chondrocyte implantation repairs. We evaluated 66 autologous chondrocyte implantation repairs in 57 patients, 55 of whom had histology, indentometry, and International Cartilage Repair Society repair scoring at reoperation for mechanical symptoms or pain. International Knee Documentation Committee scores were used to address clinical outcome. Maximum stiffness, normalized stiffness, and International Cartilage Repair Society repair scoring were higher for hyaline articular cartilage repairs compared with fibrocartilage, with no difference in clinical outcome. Reoperations revealed 32 macroscopically abnormal repairs (Group B) and 23 knees with normal-looking repairs in which symptoms leading to arthroscopy were accounted for by other joint disorders (Group A). In Group A, 65% of repairs were either hyaline or hyaline-like cartilage compared with 28% in Group B. Autologous chondrocyte repairs composed of fibrocartilage showed more morphologic abnormalities and became symptomatic earlier than hyaline or hyaline-like cartilage repairs. The hyaline articular cartilage repairs had biomechanical properties comparable to surrounding cartilage and superior to those associated with fibrocartilage repairs.

  7. Delineation of sympatric morphotypes of lake trout in Lake Superior

    Science.gov (United States)

    Moore, Seth A.; Bronte, Charles R.

    2001-01-01

    Three morphotypes of lake trout Salvelinus namaycush are recognized in Lake Superior: lean, siscowet, and humper. Absolute morphotype assignment can be difficult. We used a size-free, whole-body morphometric analysis (truss protocol) to determine whether differences in body shape existed among lake trout morphotypes. Our results showed discrimination where traditional morphometric characters and meristic measurements failed to detect differences. Principal components analysis revealed some separation of all three morphotypes based on head and caudal peduncle shape, but it also indicated considerable overlap in score values. Humper lake trout have smaller caudal peduncle widths to head length and depth characters than do lean or siscowet lake trout. Lean lake trout had larger head measures to caudal widths, whereas siscowet had higher caudal peduncle to head measures. Backward stepwise discriminant function analysis retained two head measures, three midbody measures, and four caudal peduncle measures; correct classification rates when using these variables were 83% for leans, 80% for siscowets, and 83% for humpers, which suggests the measures we used for initial classification were consistent. Although clear ecological reasons for these differences are not readily apparent, patterns in misclassification rates may be consistent with evolutionary hypotheses for lake trout within the Laurentian Great Lakes.

  8. The Anesthetic Effect of Anterior Middle Superior Alveolar Technique (AMSA)

    Science.gov (United States)

    de Souza Tolentino, Lívia; Barbisan Souza, André; Girardi, Ana Alice; Romito, Giuseppe Alexandre; Araújo, Maurício Guimarães

    2015-01-01

    Anesthesia of the soft and hard tissues of the maxilla may require up to 5 injections. Thus, the aim of this study was to evaluate the anesthetic efficacy of the anterior middle superior alveolar (AMSA) and supraperiosteal injection techniques during subgingival scaling and root planing (SRP). Thirty individuals with periodontitis were scheduled for SRP on the buccal aspect of teeth in the anterior maxilla. Before SRP, on a randomly chosen side of the maxilla, the supraperiosteal injection was performed in 1 session, while the AMSA injection was conducted in the contralateral side of the same patient in another session. Immediately after each SRP session, patients rated their pain perception during the procedure with a visual analog scale. No statistically significant differences in mean pain ratings during SRP were found after both anesthetic techniques (P > .05). This preliminary study demonstrated that the AMSA and supraperiosteal injection techniques provided similar anesthetic comfort during SRP. The AMSA injection could be an alternative to anesthetize the buccal aspect of maxilla, without the undesirable effects on facial structures such as the upper lip, nostrils, and lower eyelids. However, further randomized clinical trials with larger samples are necessary to confirm such results. PMID:26650493

  9. Vowel sound extraction in anterior superior temporal cortex.

    Science.gov (United States)

    Obleser, Jonas; Boecker, Henning; Drzezga, Alexander; Haslinger, Bernhard; Hennenlotter, Andreas; Roettinger, Michael; Eulitz, Carsten; Rauschecker, Josef P

    2006-07-01

    We investigated the functional neuroanatomy of vowel processing. We compared attentive auditory perception of natural German vowels to perception of nonspeech band-passed noise stimuli using functional magnetic resonance imaging (fMRI). More specifically, the mapping in auditory cortex of first and second formants was considered, which spectrally characterize vowels and are linked closely to phonological features. Multiple exemplars of natural German vowels were presented in sequences alternating either mainly along the first formant (e.g., [u]-[o], [i]-[e]) or along the second formant (e.g., [u]-[i], [o]-[e]). In fixed-effects and random-effects analyses, vowel sequences elicited more activation than did nonspeech noise in the anterior superior temporal cortex (aST) bilaterally. Partial segregation of different vowel categories was observed within the activated regions, suggestive of a speech sound mapping across the cortical surface. Our results add to the growing evidence that speech sounds, as one of the behaviorally most relevant classes of auditory objects, are analyzed and categorized in aST. These findings also support the notion of an auditory "what" stream, with highly object-specialized areas anterior to primary auditory cortex. 2005 Wiley-Liss, Inc.

  10. Teaching condom use skills: practice is superior to observation.

    Science.gov (United States)

    Calsyn, Donald A; Hatch-Maillette, Mary A; Doyle, Suzanne R; Cousins, Sarah; Chen, TeChieh; Godinez, Melinda

    2010-10-01

    Men exposed to a condom skills practice exercise were hypothesized to perform better on condom skills measures than those exposed only to a demonstration or to no intervention. As part of a larger National Institute on Drug Abuse (NIDA) Clinical Trials Network HIV Prevention protocol, men in substance abuse treatment were administered male and female condom use skills measures (MCUS, FCUS) at preintervention, 2 weeks, 3 months, and 6 months postintervention. The MCUS and FCUS scores were compared for 3 intervention exposure groups (demonstration only [DO, n = 149], demonstration plus practice [D+P; n = 112], attended no sessions [NS, n = 139]) across the 4 assessment time points using a mixed effects linear regression model. There is a statistically significant intervention group-by-time effect (P < .0001) for both the MCUS and FCUS. Post hoc, pairwise linear trends across time indicated that for both the MCUS and the FCUS, the D+P group is significantly superior to the DO group and the NS group.

  11. Reproductive success of herring gulls breeding on Lake Superior

    Energy Technology Data Exchange (ETDEWEB)

    Shutt, J.L. [Canadian Wildlife Service, Hull, Quebec (Canada)

    1994-12-31

    Herring gulls breed in the vicinity of three pulp mills located on the north shore of Lake Superior. The impacts of exposure to effluents produced by these mills on various aspects of the reproductive biology of this species have been monitored since 1992. Reproductive success at these sites has been either zero or below the level necessary to maintain a stable population. Levels of dioxins and furans in the eggs and tissues of herring gulls did not show any consistent trends between the exposed and control sites and were generally low. Additionally, TCDD TEQs calculated for the same colonies, with the inclusion of several non ortho-substituted PCBs, were well below levels thought to result in reproductive impairment of herring gulls. However, plasma and liver concentrations of retinol were depressed and variable at several colonies, indicating potential diet differences between the study sites. Further determination of food types consumed at the control and exposed sites revealed that fish, the traditional diet of this species, was a small or insignificant component of the diet. Food type was also correlated with contaminant burden and reproductive output. Previously collected data as well as current results will be discussed.

  12. The mesoproterozoic midcontinent rift system, Lake Superior region, USA

    Science.gov (United States)

    Ojakangas, R.W.; Morey, G.B.; Green, J.C.

    2001-01-01

    Exposures in the Lake Superior region, and associated geophysical evidence, show that a 2000 km-long rift system developed within the North American craton ??? 1109-1087 Ma, the age span of the most of the volcanic rocks. This system is characterized by immense volumes of mafic igneous rocks, mostly subaerial plateau basalts, generated in two major pulses largely by a hot mantle plume. A new ocean basin was nearly formed before rifting ceased, perhaps due to the remote effect of the Grenville continental collision to the east. Broad sagging/subsidence, combined with a system of axial half-grabens separated along the length of the rift by accommodation zones, provided conditions for the accumulation of as much as 20 km of volcanic rocks and as much as 10 km of post-rift clastic sediments, both along the rift axis and in basins flanking a central, post-volcanic horst. Pre-rift mature, quartzose sandstones imply little or no uplift prior to the onset of rift volcanism. Early post-rift red-bed sediments consist almost entirely of intrabasinally derived volcanic sediment deposited in alluvial fan to fluvial settings; the exception is one gray to black carbon-bearing lacustrine(?) unit. This early sedimentation phase was followed by broad crustal sagging and deposition of progressively more mature red-bed, fluvial sediments with an extra-basinal provenance. ?? 2001 Elsevier Science B.V. All rights reserved.

  13. Gallbladder cancer with tumor thrombus in the superior vena cava

    Institute of Scientific and Technical Information of China (English)

    Sandeep Batra; Dinesh Chandra Doval; Ullas Batra; Pandalanghat Suresh; Amit Dhiman; Vineet Talwar

    2010-01-01

    BACKGROUND: Gastrointestinal cancers, especially pancreato-biliary cancers, are frequently associated with or are complicated by thromboembolic phenomena due to hypercoagulability and/or altered venous drainage, especially of the abdomen and lower limbs. This report describes an unusual and interesting case of gallbladder carcinoma developing a viable tumor thrombus in the superior vena cava (SVC) with resultant SVC obstruction, while on geiftinib-based anti-epidermal growth factor receptor (EGFR) therapy. METHODS: A 60-year-old woman was incidentally diagnosed to have gallbladder cancer on cholecystectomy. She had disease recurrence and received systemic chemotherapy followed by geiftinib-based anti-EGFR therapy. Subsequently, while on geiftinib-based therapy, she presented with clinical signs and symptoms suggestive of SVC thrombosis. RESULTS: A whole body PET scan revealed a metabolically active tumor thrombus in the SVC, besides other sites of metabolically active disease inclusive of the lung parenchyma, lymph nodes and abdomen. She was treated with anti-thrombotics and external beam radiotherapy directed to the SVC thrombus leading to symptomatic relief. She continues to survive on the day of writing this report. CONCLUSIONS: This rare complication, though theoretically possible, is unreported because of the short overall survival of advanced gallbladder cancer patients. This highlights that with the availability of better chemotherapeutic/biotherapeutic agents for increasing in the lifespan of cancer patients, we may come across such cases more frequently in the future.

  14. A Astronomia no Ensino Superior Brasileiro entre 1808 e 1889

    Science.gov (United States)

    Bretones, Paulo S.; Videira, Antonio A. P.

    2003-05-01

    Este artigo apresenta os principais eventos ocorridos na história do ensino de astronomia nos cursos superiores que existiram no Brasil desde a chegada da Família Real portuguesa em 1808 até o final do período monárquico. Para compor esse esboço histórico, utilizamos, principalmente, livros didáticos, regulamentos, decretos e leis responsáveis pelas organizações dos conteúdos oferecidos e das carreiras dos responsáveis pela disciplina. Na análise do material empregado, investigamos a presença de concepções filosóficas e científicas, que podem ter norteado os conteúdos disciplinares. Não realizamos nenhuma comparação com o ensino de astronomia em outros países. Concluímos mostrando que o estudo de astronomia, durante o período monárquico, foi mais direcionado para a formação d engenheiros do que astrônomos. Gostaríamos de observar que o presente artigo não tem a pretensão de abordar o assunto de maneira completa e detalhada.

  15. Modeling the value of strategic actions in the superior colliculus

    Directory of Open Access Journals (Sweden)

    Dhushan Thevarajah

    2010-02-01

    Full Text Available In learning models of strategic game play, an agent constructs a valuation (action value over possible future choices as a function of past actions and rewards. Choices are then stochastic functions of these action values. Our goal is to uncover a neural signal that correlates with the action value posited by behavioral learning models. We measured activity from neurons in the superior colliculus (SC, a midbrain region involved in planning saccadic eye movements, in monkeys while they performed two saccade tasks. In the strategic task, monkeys competed against a computer in a saccade version of the mixed-strategy game “matching-pennies”. In the instructed task, stochastic saccades were elicited through explicit instruction rather than free choices. In both tasks, neuronal activity and behavior were shaped by past actions and rewards with more recent events exerting a larger influence. Further, SC activity predicted upcoming choices during the strategic task and upcoming reaction times during the instructed task. Finally, we found that neuronal activity in both tasks correlated with an established learning model, the Experience Weighted Attraction model of action valuation (Ho, Camerer, and Chong, 2007. Collectively, our results provide evidence that action values hypothesized by learning models are represented in the motor planning regions of the brain in a manner that could be used to select strategic actions.

  16. Trauma to the Superior Mesenteric Artery and Superior Mesenteric Vein: A Narrative Review of Rare but Lethal Injuries.

    Science.gov (United States)

    Phillips, B; Reiter, S; Murray, E P; McDonald, D; Turco, L; Cornell, D L; Asensio, J A

    2017-09-05

    Mesenteric vessels, including the superior mesenteric artery (SMA) and vein (SMV), provide and drain the rich blood supply of the midgut and hindgut. SMA and SMV injuries are rare and often lethal. Clinical management of these injuries is not well established, but treatment options include operative, non-operative, and endovascular strategies. A narrative review of the literature was conducted using MEDLINE Complete-EBSCO. Relevant studies, specifically those focusing on diagnosis and management of SMA and SMV injuries, were selected. Only original reports and collected series were selected to prevent duplication of cases. A search of the literature for mesenteric arterial injuries yielded 87 studies. Vessel-specific breakdown of the studies yielded 40 with SMA injuries and 41 with SMV injuries. These searches were winnowed to 26 individual studies, which were included in this collective review. Limitations of this study are similar to all narrative literature reviews: the dependence on previously published research and availability of references as outlined in our methodology. Although historically rare, mesenteric vessel injuries are seen with increasing incidence and continue to present a challenge to trauma surgeons due to their daunting mortality rates. Currently, universal treatment guidelines do not exist, but the various options for their management have been extensively reviewed in the literature.

  17. Age and growth of the whitefish in Lake Superior

    Science.gov (United States)

    Dryer, William R.

    1963-01-01

    The average annual commercial production of whitefish in the U.S. waters of Lake Superior dropped from 2,194,000 pounds in 1879-1908 to 504,000 pounds in 1911-59. The modern production, though far below the earlier, has accounted for more than 10 percent of the total value of the fishery in all but one of the last 20 years. Data are given on growth rate, age and year-class composition, size distribution, and length-weight relation of 1,800 fish collected in 1957-59 at Bayfield, Wis., and Marquette, Whitefish Point, and Dollar Settlement, Mich. Studies of the body-scale relation, sex ratio, and age and size at maturity were limited to fish collected at Bayfield. The age composition and mean age varied widely by port and year of capture. Oldest fish were those of the 1957 Bayfield samples which were dominated by age group VII and averaged 5.5 years old. The youngest were from Whitefish Point in 1959; age-group III was dominant, and the mean age was 3.2 years. The evidence on the strength of year classes was not clear-cut, but it was obvious that fluctuations in stocks of different areas were largely independent. The percentage of legal-size fish (17 inches or longer) in age groups ranged widely; only 8.6 percent of the V group were legal in the 1957 Bayfield collections, whereas 100 percent of fish of the same age were legal in the 1957-59 collections from Whitefish Point. The weight of whitefish in the combined samples increased as the 3.2408 power of the length. The growth rate from the fastest to the slowest growing stocks ranked as follows: Whitefish Point; Dollar Settlement and Marquette (fish from the two ports reversed ranks after 3 years); Bayfield. The major differences in growth in length among the various stocks occurred during the first years of life. Beyond the fifth year the annual increments were nearly the same in all stocks. The whitefish from Whitefish Point, Dollar Settlement, and Marquette are among the fastest growing in the Great Lakes. The

  18. Estudo clínico e histológico das pálpebras e conjuntiva hígidas submetidas ao tratamento tópico com soluções anestésicas em coelhos Clinical and histological evaluation of healthy eyelid and conjunctiva subject to local treatment with anesthetic solutions in rabbits

    Directory of Open Access Journals (Sweden)

    A.V.C. Amaral

    2013-02-01

    were subject to euthanasia, for the purpose of conjunctiva, eyelids and third eyelids histological evaluation. At the clinical exam, different grades of episcleritis were found in all rabbits in G2 group and only in 17.8% of the rabbits in G1 group. Eye and eyelid histologic evaluation of G2 group revealed an upgrade of goblet cells and eosinophil number, lymphoid follicle proliferation and increase of interstitial space in the eyelids. We could conclude that 1% tetracaine associated with 0.1% phenylephrine eye drop caused more eyelid and ocular conjunctiva toxicity than 0.5% proparacaine eye drop.

  19. The role of the superior laryngeal nerve in esophageal reflexes.

    Science.gov (United States)

    Lang, I M; Medda, B K; Jadcherla, S; Shaker, R

    2012-06-15

    The aim of this study was to determine the role of the superior laryngeal nerve (SLN) in the following esophageal reflexes: esophago-upper esophageal sphincter (UES) contractile reflex (EUCR), esophago-lower esophageal sphincter (LES) relaxation reflex (ELIR), secondary peristalsis, pharyngeal swallowing, and belch. Cats (N = 43) were decerebrated and instrumented to record EMG of the cricopharyngeus, thyrohyoideus, geniohyoideus, and cricothyroideus; esophageal pressure; and motility of LES. Reflexes were activated by stimulation of the esophagus via slow balloon or rapid air distension at 1 to 16 cm distal to the UES. Slow balloon distension consistently activated EUCR and ELIR from all areas of the esophagus, but the distal esophagus was more sensitive than the proximal esophagus. Transection of SLN or proximal recurrent laryngeal nerves (RLN) blocked EUCR and ELIR generated from the cervical esophagus. Distal RLN transection blocked EUCR from the distal cervical esophagus. Slow distension of all areas of the esophagus except the most proximal few centimeters activated secondary peristalsis, and SLN transection had no effect on secondary peristalsis. Slow distension of all areas of the esophagus inconsistently activated pharyngeal swallows, and SLN transection blocked generation of pharyngeal swallows from all levels of the esophagus. Slow distension of the esophagus inconsistently activated belching, but rapid air distension consistently activated belching from all areas of the esophagus. SLN transection did not block initiation of belch but blocked one aspect of belch, i.e., inhibition of cricopharyngeus EMG. Vagotomy blocked all aspects of belch generated from all areas of esophagus and blocked all responses of all reflexes not blocked by SLN or RLN transection. In conclusion, the SLN mediates all aspects of the pharyngeal swallow, no portion of the secondary peristalsis, and the EUCR and ELIR generated from the proximal esophagus. Considering that SLN is not

  20. O ENSINO SUPERIOR EM TURISMO: HUMANO OU MERCADO?

    Directory of Open Access Journals (Sweden)

    Waléria Thabata Roldão Niquini

    2013-06-01

    Full Text Available Desde La creación de la educación superior en el Turismo en Brasil, en La década de 1970, se han producido algunas discusiones en relación a la formación del estudiante y su desempeño en el mercado laboral. Sin embargo hay varios puntos educativos significantes incluso antes de la aparición de la inserción profesional. La preparación de los estudiantes, las acciones de los maestros en la esfera de investigación y extensión y la necesidad del pensamiento crítico son supuestos que poden justificar tal curso mientras que la práctica educativa libertadora. Estas son las cuestiones discutidas en esta investigación destinada a comprender las perspectivas docente y dicente, en la licenciatura en Turismo, sobre la relación entre la enseñanza y el aprendizaje y sus aspectos esenciales, en una más amplia visión y menos fragmentada, entre la destacada dicotomía y el mercado de laboro y el pensamiento crítico científico. Se concluye que el debate académico sobre la educación en el Turismo todavía se disocia sólo entre los intereses del mercado y las discusiones humanas, sin una integración profunda en la relación enseñanza-aprendizaje.

  1. Surgical treatment of superior oblique palsy: Predictors of outcome

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    Pilar Merino Sanz

    2017-01-01

    Full Text Available Purpose: The purpose of this study was to evaluate the incidence and outcome of surgically treated superior oblique palsy (SOP and the factors involved in its resolution. Methods: We performed a retrospective study of 76 patients who underwent surgery for SOP. We recorded data from the physical examination and the number and type of procedures performed. Favorable outcome was defined as resolution of or improvement in torticollis (≤5° and diplopia in primary position (PP and downgaze or as vertical deviation (VD <5 prism diopters (pd in PP and 10 pd in the oblique diagnostic position. Results: Mean age was 33.12 years. Congenital SOP was the most frequent type (65.8%. Mean preoperative VD was 15.89 ± 9.94 pd, decreasing to 3.07 ± 4.36 pd after surgery. Associated horizontal deviation was recorded in 51.32% of cases. The mean number of procedures was 1.37 ± 0.62 (range 1–4, with 69.7% of patients requiring only one procedure. The mean number of muscles operated on was 1.96 ± 1.01 (inferior oblique being the most frequent. A greater reduction in VD after surgery was observed in patients with congenital SOP (P = 0.04. Although none of the factors evaluated influenced surgical outcome, amblyopic patients had a greater risk of reoperation (P = 0.04. A favorable outcome was achieved in 75% of cases. Mean follow-up was 37.08 months. Conclusion: Congenital SOP was twice as frequent as acquired SOP and although surgery was successful in most cases, a greater reduction in VD was obtained in congenital cases. Amblyopia was identified as a risk factor for reoperation.

  2. Robot-assisted partial nephrectomy: Superiority over laparoscopic partial nephrectomy.

    Science.gov (United States)

    Shiroki, Ryoichi; Fukami, Naohiko; Fukaya, Kosuke; Kusaka, Mamoru; Natsume, Takahiro; Ichihara, Takashi; Toyama, Hiroshi

    2016-02-01

    Nephron-sparing surgery has been proven to positively impact the postoperative quality of life for the treatment of small renal tumors, possibly leading to functional improvements. Laparoscopic partial nephrectomy is still one of the most demanding procedures in urological surgery. Laparoscopic partial nephrectomy sometimes results in extended warm ischemic time and severe complications, such as open conversion, postoperative hemorrhage and urine leakage. Robot-assisted partial nephrectomy exploits the advantages offered by the da Vinci Surgical System to laparoscopic partial nephrectomy, equipped with 3-D vision and a better degree in the freedom of surgical instruments. The introduction of the da Vinci Surgical System made nephron-sparing surgery, specifically robot-assisted partial nephrectomy, safe with promising results, leading to the shortening of warm ischemic time and a reduction in perioperative complications. Even for complex and challenging tumors, robotic assistance is expected to provide the benefit of minimally-invasive surgery with safe and satisfactory renal function. Warm ischemic time is the modifiable factor during robot-assisted partial nephrectomy to affect postoperative kidney function. We analyzed the predictive factors for extended warm ischemic time from our robot-assisted partial nephrectomy series. The surface area of the tumor attached to the kidney parenchyma was shown to significantly affect the extended warm ischemic time during robot-assisted partial nephrectomy. In cases with tumor-attached surface area more than 15 cm(2) , we should consider switching robot-assisted partial nephrectomy to open partial nephrectomy under cold ischemia if it is imperative. In Japan, a nationwide prospective study has been carried out to show the superiority of robot-assisted partial nephrectomy to laparoscopic partial nephrectomy in improving warm ischemic time and complications. By facilitating robotic technology, robot-assisted partial nephrectomy

  3. Non-Stationarity in Multisensory Neurons in the Superior Colliculus

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    Thomas J Perrault

    2011-07-01

    Full Text Available The superior colliculus (SC integrates information from multiple sensory modalities to facilitate the detection and localization of salient events. The efficacy of multisensory integration is traditionally measured by comparing the magnitude of the response elicited by a cross-modal stimulus to the responses elicited by its modality-specific component stimuli, and because there is an element of randomness in the system, these calculations are made using response values averaged over multiple stimulus presentations in an experiment. Recent evidence suggests that multisensory integration in the SC is highly plastic and these neurons adapt to specific anomalous stimulus configurations. This raises the question whether such adaptation occurs during an experiment with traditional stimulus configurations; that is, whether the state of the neuron and its integrative principles are the same at the beginning and end of the experiment, or whether they are altered as a consequence of exposure to the testing stimuli even when they are pseudo-randomly interleaved. We find that unisensory and multisensory responses do change during an experiment, and these changes are predictable. Responses that are initially weak tend to potentiate, responses that are initially strong tend to habituate, and the efficacy of multisensory integration waxes or wanes accordingly during the experiment as predicted by the principle of inverse effectiveness. These changes are presumed to reflect two competing mechanisms in the SC: potentiation reflecting increases in the expectation that a stimulus will occur at a given location, habituation reflecting decreases in stimulus novelty. These findings indicate plasticity in multisensory integration that allows animals to adapt to rapidly changing environmental events while suggesting important caveats in the interpretation of experimental data: the neuron studied at the beginning of an experiment is not the same at the end of it.

  4. Cambiar paradigmas: una experiencia en educación superior

    Directory of Open Access Journals (Sweden)

    Gisella Vargas Chinchilla

    2004-09-01

    Full Text Available

    Resumen. Una experiencia en educación superior, al estilo de investigación-acción, donde una “comunidad de aprendizaje” constituida por docentes y estudiantes, busca convertirse en entes multiplicadores del desarrollo sostenible, dentro del plan de formación de docentes de Educación Preescolar.

    Esta investigación constituye el Trabajo final de Graduación, requisito de un grupo de estudiantes para obtener el grado de Licenciadas en Educación Preescolar, en la Universidad de Costa Rica. El proceso metodológico dio inicio con un diagnóstico, para seguir con un plan de acción, organizado y desarrollado en conjunto, estudiantes y docentes, para culminar con la aceptación de “compromisos ambientales” asumidos por las personas participantes.

     

    Abstract. This is a research-action type of experience in higher education lived by a “learning community” conformed by teachers and students whose aim is to become fostering agents for sustainable development. The experience was carried out as part of the plan for teacher training in Preschool Education.

    This paper is the authors' Final Graduation Paper, a requirement to obtain a Licentiate degree in Preschool Education at the University of Costa Rica. The research began with a diagnosis that would lead to the implementation of an action plan that was organized and carried out jointly by the students and their teachers. The project finished with the participants' acceptance of some “environmental commitments”.

  5. Spatiotemporal structure of visual receptive fields in macaque superior colliculus.

    Science.gov (United States)

    Churan, Jan; Guitton, Daniel; Pack, Christopher C

    2012-11-01

    Saccades are useful for directing the high-acuity fovea to visual targets that are of behavioral relevance. The selection of visual targets for eye movements involves the superior colliculus (SC), where many neurons respond to visual stimuli. Many of these neurons are also activated before and during saccades of specific directions and amplitudes. Although the role of the SC in controlling eye movements has been thoroughly examined, far less is known about the nature of the visual responses in this area. We have, therefore, recorded from neurons in the intermediate layers of the macaque SC, while using a sparse-noise mapping procedure to obtain a detailed characterization of the spatiotemporal structure of visual receptive fields. We find that SC responses to flashed visual stimuli start roughly 50 ms after the onset of the stimulus and last for on average ~70 ms. About 50% of these neurons are strongly suppressed by visual stimuli flashed at certain locations flanking the excitatory center, and the spatiotemporal pattern of suppression exerts a predictable influence on the timing of saccades. This suppression may, therefore, contribute to the filtering of distractor stimuli during target selection. We also find that saccades affect the processing of visual stimuli by SC neurons in a manner that is quite similar to the saccadic suppression and postsaccadic enhancement that has been observed in the cortex and in perception. However, in contrast to what has been observed in the cortex, decreased visual sensitivity was generally associated with increased firing rates, while increased sensitivity was associated with decreased firing rates. Overall, these results suggest that the processing of visual stimuli by SC receptive fields can influence oculomotor behavior and that oculomotor signals originating in the SC can shape perisaccadic visual perception.

  6. Experiencing the changing climate on the shores of Lake Superior

    Science.gov (United States)

    Akerlof, K.; Maibach, E.

    2011-12-01

    The Great Lakes of the United States - the largest freshwater system in the world - have been termed "the canary in the coal mine" of environmental change. To assess if and how residents of Alger County, Michigan are experiencing changes in climate on the shores of Lake Superior, during the summer of 2010 we conducted a representative household mail survey in collaboration with a national lakeshore and watershed partnership. A total of 765 adult residents (18 years or older) responded to the survey; a 57% survey completion rate. We content analyzed respondents' open-ended characterizations of how they have personally experienced global warming, and compared the results with land surface and storm data for the same geographic region to see whether public perceptions of local changes match trends in National Climatic Data Center data. Just over a quarter of residents (27%) indicated that they had personally experienced global warming. Those who had were most likely to say that they had experienced global warming locally (as opposed to in other locations of the country or globally), and most frequently cited changes in seasons, weather, lake levels, and animals or plant species. However, some local public perceptions appeared to conflict with weather records. For example, residents were more likely to say that they had been experiencing less snow in the winters, while NCDC data suggests the reverse is true. As climate changes differentially in regions across the United States, the public will in turn experience its physical impacts in distinct ways that are unique to each landscape. This may be counter-intuitive to a public that increasingly experiences the world, and issues such as climate change, through sources of information such as national news media that operate at much larger geographic scales. Understanding where these forms of cognitive dissonance may arise may assist researchers, educators, and communicators in furthering discourses with the public about

  7. [Acupoint catgut-embedding therapy: superiorities and principles of application].

    Science.gov (United States)

    Zhang, Xuan-Ping; Jia, Chun-Sheng; Wang, Jian-Ling; Shi, Jing; Zhang, Xin; Li, Xiao-Feng; Xu, Xiao-Kang; Qin, Liang; Zhang, Mei-Ling; Kang, Su-Gang; Duan, Xiao-Dong

    2012-10-01

    To analyze the superiorities of acupoint catgut-embedding therapy, discuss its law of clinical application and provide scientific decision-making for clinical treatment. Literatures on acupoint catgut-embedding therapy in the recent 40 years were selected, input, examined and verified, picked up and analyzed by establishing database with the modern computer technology. (1) One thousand and seventy-five literatures were input. It shows that the acupoint catgut-embedding therapy has an extensive application in all departments, especially in the internal department, accounting for 48.54% (50/103) of the total disease category. It has the most extensive application on treatment of epigastric pain, with the frequency of 102 times, and obesity of 74 times. The next is surgery, accounting for 14.56% (15/103). The major application is on low back pain and leg pain with the frequency of 79 times. Psoriasis, with the frequency of 30 times, holds the major application in dermatological department. And blepharoplasty, with the frequency of 30 times, gains the most application in department of ophthalmology and otorhinolaryngology. (2) In the included literatures, selection of adjacent acupoints and distal acupoints are held as the major method of acupoint selection. The adjusted lumbar puncture needle is taken as the major tool for the acupoint catgut-embedding therapy. And catguts of different sizes are adopted for the operation. (3) Analysis of the therapeutic effect shows that acupoint catgut-embedding therapy has obvious effect in all departments, especially in surgery and dermatology, with the total effective rate over 90%. Epigastric pain, obesity, epilepsy, asthma, abdominal pain, facial paralysis and constipation of the internal medicine, low back pain and leg pain of the surgical department, psoriasis of the dermatological department and blepharoplasty of the department of ophthalmology and otorhinolaryngology are considered as the dominant diseases for acupoint

  8. MRI appearance of the superior transverse scapular ligament

    Energy Technology Data Exchange (ETDEWEB)

    Simeone, F.J.; Bredella, Miriam A.; Chang, Connie Y.; Torriani, Martin; Huang, Ambrose J. [Massachusetts General Hospital, Department of Radiology, Division of Musculoskeletal Imaging and Intervention, Boston, MA (United States)

    2015-11-15

    The superior transverse scapular ligament (STSL) forms the roof of the suprascapular notch, which is the most common location of entrapment of the suprascapular nerve, a cause of shoulder pain and weakness. The purpose of this study is to determine the frequency of visualization of the STSL on routine shoulder MRIs, to identify the sequences and imaging planes on which it is visualized most frequently, and to describe its typical MRI appearance, none of which have been previously addressed in the radiologic literature. One hundred twenty-one consecutive shoulder MRIs were reviewed for the presence or absence of the STSL, including the imaging plane and sequence that best depicted the ligament. Dimensions of the ligament were recorded. Fifty four of 121 shoulder MRIs were technically adequate for visualization of the STSL, and it was identified on 51 of these studies (94 %). There was no statistically significant difference between 1.5-T and 3-T systems. The best individual sequence for visualizing the STSL was the sagittal T1-weighted sequence, in which the STSL was visible on 75/80 technically adequate sequences (94 %). The sagittal plane was the best plane for visualizing the STSL, in which it was visible on 65/69 technically adequate studies (94 %). The STSL on average measured 12.8 ± 1.5 mm in transverse dimension. The STSL can be visualized on the majority of shoulder MRIs and is best seen on sagittal T1-weighted images on our imaging protocol. Evaluation of the STSL can potentially help in identifying pathologic conditions affecting the suprascapular nerve. (orig.)

  9. Percutaneous treatment of superior vena cava syndrome using metallic stents

    Energy Technology Data Exchange (ETDEWEB)

    De Gregorio Ariza, Miguel Angel; Gimeno, Maria Jose; Alfonso, Eduardo; Mainar, Antonio; Medrano, Joaquin; Lopez-Marin, Paloma [Department of Interventional Radiology, ' ' Lozano Blesa' ' University Hospital, Avda. San Juan Bosco 15, 50009 Zaragoza (Spain); Gamboa, Pablo [Division of Interventional Radiology, Ohio State University Hospital, Columbus, Ohio (United States); Tobio, Ricardo [Interventional Radiology, Clinica de la Zarzuela, Madrid (Spain); Herrera, Marcos [Division of Interventional Radiology, University of Minnesota, Minneapolis, Minnesota (United States)

    2003-04-01

    The purpose of this study was to evaluate the results of treatment of superior vena cava syndrome (SVCS) in patients with benign and malignant disease using expandable metallic stent. From January 1995 to April 2000, 87 expandable stents were implanted in 82 patients (59 men, 23 women; mean age 57.8 years, age range 39-79 years) for the treatment of SVCS. The SVCS was defined as symptomatic bilateral obstruction of venous drainage from head, neck and upper extremities. In 68 patients SVCS was due to malignant neoplasia, and in 14 cases it was due to benign aetiology. All patients were treated with expandable stent. We implanted 81 Wallstent prostheses and 6 Palmaz stents. Adjuvant thrombolysis was applied in 12 patients who required fibrinolysis. After recanalization, the stent was implanted in all cases in SVC (infra- or supra-azygos vein). All patients were treated with heparin of low molecular weight (HBPM) during 6 months. Patency was analyzed according to clinical symptoms and Doppler US or venograms exploration. Technical success was observed in all cases. Clinical success was reached in 78 of 82 patients (95.1%) (absence of symptoms in 2 or 3 days). Four patients suffered immediate thrombosis which required fibrinolitic treatment with a new prosthesis placement in 1 case. The follow-up for the malignant process was of 7.1 months (range 1-39 months) and in benign cases was 31.2 months (range 11-61 months). Sixty-two (91.1%) patients with malignancy died without SVCS symptomatology. All the patients with benign pathology are alive. Clinical primary patency in malignant cases was 87% with assisted patency of 96.2%. Endovascular therapy using metallic stent and thrombolysis is a successful method to treat SVCS due to benign or malignant aetiology. (orig.)

  10. Superior mesenteric artery outcomes after fenestrated endovascular aortic aneurysm repair.

    Science.gov (United States)

    Lala, Salim; Knowles, Martyn; Timaran, David; Baig, Mirza Shadman; Valentine, James; Timaran, Carlos

    2016-09-01

    The Zenith (Cook Medical, Bloomington, Ind) fenestrated endovascular graft may be designed with single-wide scallops or large fenestrations to address the superior mesenteric artery (SMA). Misalignment of the SMA with an unstented scallop or a large fenestration is possible. This study assessed SMA outcomes after fenestrated endovascular aortic aneurysm repair (FEVAR). During an 18-month period, 47 FEVARs were performed at a single institution. For analysis, patients were grouped according to unstented (n = 23) vs stented (n = 24) SMA scallops/fenestrations. The Institutional Review Board approved this single-institution observational study. Because this was a retrospective review of the data, patient consent was unnecessary for the study. Technical success for FEVAR was 100%. The median follow-up period was 7.7 months (range, 1-16 months). Nine of 21 patients (43%) in the unstented group had some degree of misalignment of the SMA (range, 9%-71%). Among these, four patients (44%) developed complications: three SMA stenoses and one occlusion. The mean peak systolic velocity in patients with and without SMA misalignment was 317.8 cm/s vs 188.4 cm/s (P < .08), respectively. No misalignment occurred in the stented group, and only one of 19 patients (5%) developed an SMA stenosis that required angioplasty. Overall, patients with unstented SMAs had significantly more adverse events directly attributable to SMA misalignment than the stented group (44% vs 5%, respectively; P < .05). Misalignment of the SMA with the use of unstented unreinforced scallops or fenestrations occurs frequently. Routine stenting of single-wide and large fenestrations, when feasible, may be a safer option for patients undergoing FEVAR. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

  11. A surgical view of the superior nasal turbinate: anatomical study.

    Science.gov (United States)

    Orhan, Mustafa; Govsa, Figen; Saylam, Canan

    2010-06-01

    Differences of the superior nasal turbinate (SNT), presence of the supreme nasal turbinate (SpNT) and measurements of opening sphenoid sinus (OSS) are consistent anatomical landmarks that allow for safe entrances, such as posterior ethmoidectomy and sphenoid sinusotomy. The purpose of study was to investigate the anatomical details of the SNT for approaching the OSS on 20 specimens of adult cadavers under an operating microscope. The SNT and SpNT were localized more perpendicular than parallel to their axes. The SpNT structure was observed in 12 specimens (60%) and it was classified into three types. Type A SpNT was shortest of all turbinates (58.3%). In types B and C, SpNT was equal or larger than the SNT. These types were seen in 41.7% of specimens. In 11 specimens, posterior ethmoidal cells opened to supreme nasal meatus. In 7 specimens, there was one opening to supreme nasal meatus, while 2 openings were detected in 12 specimens, and 3 openings were seen in 1 specimen. All these openings belonged to posterior ethmoidal cells. To determine the position of the OSS, distances between some anatomical points were measured. In cases where the SpNT is present or the SpNT is bigger than the SNT, it is certain that a different method will be applied during the procedure in the nasal cavity. The SNT and the SpNT may easily be injured by unrecognized dissection in types B and C, leading to the disruption of its olfactory neuroepithelium and possibly to postoperative hyposmia.

  12. The Superior Labrum, Anterior-to-Posterior ’SLAP’ Lesion

    Science.gov (United States)

    2006-10-01

    and no muscular atrophy. The capsular structures were intact with no evidence of Bankart or Hill Sachs lesions . The superior Military Medicine...include 1) anteroinferior Bankart -type labral lesions in continuity with SLAP lesions , 2) biceps tendon separation with an unstable flap tear of the...The Superior Labrum, Anterior-to-Posterior ‘SLAP’ Lesion Radiology Corner The Superior Labrum, Anterior-to-Posterior ‘SLAP’ Lesion Guarantor

  13. Superior mediastinal widening from traumatic posterior dislocation of sternoclavicular joint: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sung Ah; Juhng, Seon Kwan [Wonkang Univ. School of Medicine, Iksan (Korea, Republic of)

    1999-08-01

    Superior mediastinal widening, as seen on chest radiographs of traumatized patients, has been considered the hallmark of mediastinal injury. The usual causes of superior mediastinal widening are rupture of the aorta, esophagus or trachea, and hematoma as a result of spinal fracture. Posterior dislocation of the sternoclavicular joint is rarely a cause. We report a case of superior mediastinal widening resulting from traumatic posterior dislocation of the sternoclavicular joint, and describe the CT findings, including those of 3-D imaging.

  14. Congenital absence of the azygos vein with persistent left superior vena cava: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Yim, Young Hee; Yi, Jeong Geun; Song, In Young; Park, Jeong Hee [Dept. of Radiology, Konkuk University School of Medicine, Seoul (Korea, Republic of)

    2014-03-15

    Absence of the azygos vein is a very rare variant of venous tributary arrangement which has been reported only in few cases so far. We hereby introduce the chest radiographic and computed tomographic findings of the congenital absence of the azygos vein with bilateral superior vena cava, incidentally detected during a follow-up for rectal cancer. The hemiazygos vein is drained into persistent left superior vena cava via left superior intercostal vein, so called the 'aortic nipple'.

  15. Use of hyaluronic acid gel in the treatment of lagophthalmos in sunken superior sulcus syndrome.

    Science.gov (United States)

    Leyngold, Ilya M; Berbos, Zachary J; McCann, John D; Pariseau, Brett; Leyngold, Ariel R; Anderson, Richard L

    2014-01-01

    To evaluate the use of hyaluronic acid gel in the management of lagophthalmos in sunken superior sulcus syndrome. Lagophthalmos associated with orbital fat atrophy and deep superior sulcus is a known entity described previously. Orbital fat atrophy results in deep superior sulcus where skin, orbicularis muscle, and orbital septum retract posteriorly in the deep superior sulcus, leading to lagophthalmos from suboptimal orbicularis function and effective skin shortening. The authors define this condition as sunken superior sulcus syndrome (SSSS) when the deep superior sulcus leads to exposure keratopathy. Thus, the syndrome consists of deep superior sulcus, lagophthalmos, and exposure keratopathy. Although the use of hyaluronic acid gel has been proposed as a management option for paralytic lagophthalmos, its application in the treatment of lagophthalmos in SSSS has not been reported. In this study, 5 patients (10 eyelids) with SSSS were injected with hyaluronic acid gel in the superior sulcus of the upper eyelid. Injected amount was titrated until the desired point was reached: complete or nearly complete eyelid closure. After an average follow up of 9.5 months, lagoph thalmos improved by 2 mm or 69% (p = 0.02) on the right side and by 1 mm or 71% (p = 0.01) on the left side. Most patients also reported significantly improved ocular comfort and appearance of the superior sulcus. The only complications noted were bruising and temporary uneven contour of the upper eyelid sulcus. Management of lagophthalmos in SSSS with hyaluronic acid gel is an effective and safe alternative to surgery.

  16. Cortical projections to the superior colliculus in tree shrews (Tupaia belangeri).

    Science.gov (United States)

    Baldwin, Mary K L; Wei, Haiyang; Reed, Jamie L; Bickford, Martha E; Petry, Heywood M; Kaas, Jon H

    2013-05-01

    The visuomotor functions of the superior colliculus depend not only on direct inputs from the retina, but also on inputs from neocortex. As mammals vary in the areal organization of neocortex, and in the organization of the number of visual and visuomotor areas, patterns of corticotectal projections vary. Primates in particular have a large number of visual areas projecting to the superior colliculus. As tree shrews are close relatives of primates, and they are also highly visual, we studied the distribution of cortical neurons projecting to the superior colliculus by injecting anatomical tracers into the colliculus. Since projections from visuotopically organized visual areas are expected to match the visuotopy of the superior colliculus, injections at different retinotopic locations in the superior colliculus provide information about the locations and organization of topographic areas in extrastriate cortex. Small injections in the superior colliculus labeled neurons in locations within areas 17 (V1) and 18 (V2) that are consistent with the known topography of these areas and the superior colliculus. In addition, the separate locations of clusters of labeled cells in temporal visual cortex provide evidence for five or more topographically organized areas. Injections that included deeper layers of the superior colliculus also labeled neurons in medial frontal cortex, likely in premotor cortex. Only occasional labeled neurons were observed in somatosensory or auditory cortex. Regardless of tracer injection location, we found that, unlike primates, a substantial projection to the superior colliculus from posterior parietal cortex is not a characteristic of tree shrews.

  17. Superior limb reimplantation. Case presentation. Reimplantación de miembro superior. Presentación de un caso.

    Directory of Open Access Journals (Sweden)

    Leyter Pérez Ferro

    2009-07-01

    Full Text Available Reimplantation surgery is only performed in highly specialized medical institutions. Its success is associate to the development and improvement of microsurgical techniques and to the constant training of the medical team. We present the case of a white patient of 17 years of age, who, as a result of an accident at the working place, suffered the total detachment of his upper right limb in the shoulder area. He was admitted in the emergency unit presenting hypovolemic shock and was immediately stabilized to perform later the limb reimplantation. The postsurgical development was satisfactory, proving that reimplantation can be considered a safe and functional practice in complex wounds or amputation affecting limbs.La cirugía de reimplante se realiza sólo en centros altamente especializados. Su éxito se encuentra ligado al desarrollo y perfeccionamiento de las técnicas microquirúrgicas y al entrenamiento constante del equipo de profesionales que interviene en su realización. Se presenta el caso de un paciente blanco, de 17 años de edad, que por un accidente laboral sufrió el desprendimiento total de su miembro superior derecho a nivel del hombro, y a ras con el tronco. Recibido en la unidad de urgencias médicas en estado de choque hipovolémico, fue estabilizado para realizar luego la reimplantación del miembro. La evolución postoperatoria fue satisfactoria, lo que demuestra que los reimplantes pueden ser considerados como una opción segura y viable de tratamiento, en heridas complejas o amputaciones que afecten a las extremidades.

  18. Dramatización creativa en docencia superior de ciencias

    Directory of Open Access Journals (Sweden)

    Alberto Domingo

    2013-11-01

    Full Text Available La dramatización creativa es una estrategia didáctica con muchos antecedentes (Ward, W. Creative Dramatics. D. Appleton & Co., N.Y. 1930, pero poco conocida en la enseñanza superior de ciencias (Scherr, R.E., et al. PER Conference 2010, 1289:293-296. Es una estrategia educativa sin finalidad de exhibición y percibida como improvisada por los participantes, los cuales interpretan y recrean un proceso con sus acciones guiadas sobre la marcha por un instructor. Su propósito no es formar actores ni actuar para otros, sino facilitar la adquisición de un conocimiento desde la vivencia interna y la autoobservación. En humanidades suele consistir en la interpretación de roles humanos o sociales en situaciones determinadas, pero en ciencias es una representación figurada de un proceso científico complejo, donde los participantes asumen el papel de distintos componentes o elementos que intervienen, teniendo que representar objetos o conceptos abstractos y alejados de la percepción real o de la escala humana. La dramatización facilita el aprendizaje significativo y la clarificación de conceptos abstractos, así como la comprensión de procesos complejos a través de una toma de consciencia “desde dentro” de los propios elementos que juegan un papel en los mismos (Michael, J. In pursuit of meaningful learning. Advances in Physiology Education, 2001, 25:145-158; Dee Fink, L. Creating Significant Learning Experiences: An Integrated Approach to Designing College Courses. 2003, Josey-Bass, Wiley. San Francisco, CA 94103-1741. Esta actividad promueve un aprendizaje mediante la autoobservación, aprovechando la capacidad humana natural de representar la propia percepción de fenómenos complejos para comprenderlos. La dramatización creativa estimula el pensamiento lógico e intuitivo, interioriza el conocimiento y genera un placer estético que facilita un aprendizaje significativo y memorable. En esta comunicación se presentan ejemplos pr

  19. Superior semicircular canal dehiscence in East Asian women with osteoporosis

    Directory of Open Access Journals (Sweden)

    Yu Alexander

    2012-07-01

    Full Text Available Abstract Background Superior semicircular canal dehiscence (SSCD may cause Tullio phenomenon (sound-induced vertigo or Hennebert sign (valsalva-induced vertigo due to the absence of bone overlying the SSC. We document a case series of elderly East Asian women with atypical SSCD symptoms, radiologically confirmed dehiscence and concurrent osteoporosis. Methods A retrospective record review was performed on patients with dizziness, vertigo, and/or imbalance from a neurology clinic in a community health center serving the East Asian population in Boston. SSCD was confirmed by multi-detector, high-resolution CT of the temporal bone (with Pöschl and Stenvers reformations and osteoporosis was documented by bone mineral density (BMD scans. Results Of the 496 patients seen in the neurology clinic of a community health center from 2008 to 2010, 76 (17.3% had symptoms of dizziness, vertigo, and/or imbalance. Five (6.6% had confirmed SSCD by multi-detector, high-resolution CT of the temporal bone with longitudinal areas of dehiscence along the long axis of SSC, ranging from 0.4 to 3.0 mm, as seen on the Pöschl view. Two of the 5 patients experienced motion-induced vertigo, two fell due to disequilibrium, and one had chronic dizziness. None had a history of head trauma, otologic surgery, or active intracerebral disease. On neurological examination, two patients had inducible vertigo on Dix-Hallpike maneuver and none experienced cerebellar deficit, Tullio phenomenon, or Hennebert sign. All had documented osteoporosis or osteopenia by BMD scans. Three of them had definite osteoporosis, with T-scores  Conclusions We describe an unusual presentation of SSCD without Tullio phenomenon or Hennebert sign in a population of elderly, East Asian women. There may be an association of SSCD and osteoporosis in this population. Further research is needed to determine the incidence and prevalence of this disorder, as well as the relationship of age, race

  20. The superiority of conservative resection and adjuvant radiation for craniopharyngiomas.

    Science.gov (United States)

    Schoenfeld, Adam; Pekmezci, Melike; Barnes, Michael J; Tihan, Tarik; Gupta, Nalin; Lamborn, Kathleen R; Banerjee, Anu; Mueller, Sabine; Chang, Susan; Berger, Mitchel S; Haas-Kogan, Daphne

    2012-05-01

    The purpose of this study is to evaluate the roles of resection extent and adjuvant radiation in the treatment of craniopharyngiomas. We reviewed the records of 122 patients ages 11-52 years who received primary treatment for craniopharyngioma between 1980 and 2009 at the University of California, San Francisco (UCSF). Primary endpoints were progression free survival (PFS) and overall survival (OS). Secondary endpoints were development of panhypopituitarism, diabetes insipidus (DI), and visual field defects. Of 122 patients, 30 (24%) were treated with gross total resection (GTR) without radiation therapy (RT), 3 (3%) with GTR + RT, 41 (33.6%) with subtotal resection (STR) without RT, and 48 (39.3%) with STR + RT. Median age at diagnosis was 30 years, with 46 patients 18 years or younger. Median follow-up for all patients was 56.4 months (interquartile range 18.9-144.2 months) and 47 months (interquartile range 12.3-121.8 months) for the 60 patients without progression. Fifty six patients progressed, 10 have died, 6 without progression. Median PFS was 61.1 months for all patients. PFS rate at 2 years was 61.5% (95% CI: 52.1-70.9). OS rate at 10 years was 91.1% (95% CI 84.3-97.9). There was no significant difference in PFS and OS between patients treated with GTR vs. STR + XRT (PFS; p = 0.544, OS; p = 0.735), but STR alone resulted in significantly shortened PFS compared to STR + RT or GTR (p < 0.001 for both). STR was associated with significantly shortened OS compared to STR + RT (p = 0.050) and trended to shorter OS compared to GTR (p = 0.066). GTR was associated with significantly greater risk of developing DI (56.3 vs. 13.3% with STR + XRT, p < 0.001) and panhypopituitarism (54.8 vs. 26.7% with STR + XRT, p = 0.014). In conclusion, for patients with craniopharyngioma, STR + RT may provide superior clinical outcome, achieving better disease control than STR and limiting side effects associated with aggressive surgical resection.

  1. Is thoracoscopic patent ductus arteriosus closure superior to conventional surgery?

    Science.gov (United States)

    Stankowski, Tomasz; Aboul-Hassan, Sleiman Sebastian; Marczak, Jakub; Cichon, Romuald

    2015-10-01

    A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether thoracoscopic patent ductus arteriosus (PDA) closure is superior to conventional surgery. Altogether 821 papers were found using the reported search, 11 of which represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. Eleven studies included in the analysis consisted of two prospective and three retrospective, non-randomized studies and six case series. Four included studies focused only on preterm infants, three studies enrolled neonates and the other four analysed all age groups from neonates to older children or young adults. There were no differences in mortality between video-assisted thoracoscopic surgery (VATS) and conventional surgery. Two studies suggested that VATS offers shorter operative times. Two papers observed shorter hospital stay, although the other two noted no significant difference. A large prospective trial found VATS to be associated with a lower number of postoperative complications in neonates and infants, whereas other studies suggested no significant differences in short-term postoperative complications. There is little evidence to suggest better musculoskeletal status and cosmesis in neonates following VATS. Conversion from thoracoscopy to thoracotomy described in six papers was seldom and it did not lead to any additional complications. All observational studies confirmed that both techniques are free from major adverse cardiovascular complications and these two techniques can be safely used in all patients qualified for surgical PDA closure. Two studies compared cost-effectiveness between the two techniques; one of them described VATS as significantly more cost-efficient, whereas the other study observed no difference. However, it should be noted that data

  2. Bilateral breast swelling secondary to superior vena cava obstruction and subclavian vein thrombosis

    Directory of Open Access Journals (Sweden)

    Ariadne Mayumi Yamada

    2013-07-01

    Full Text Available Superior vena cava syndrome is defined by a set of signs and symptoms secondary to superior vena cava obstruction caused principally by malignant diseases. The present report describes the case of an unusual clinical manifestation of this syndrome with bilateral breast swelling, and emphasizes the relevance of knowledge on mammographic signs of systemic diseases.

  3. Treatment for Injury of Superior Clunial Nerves by Triple Puncture Needling with Massage

    Institute of Scientific and Technical Information of China (English)

    万顺; 李静

    2002-01-01

    @@ Superior clunial nerve injury occupies a high percentage in lumbocluneal tissue injuries. It is commonly seen in winter and in athletic competition and training. The authors have treated 67 cases of pain of the superior clunial nerves by triple puncture needling combined with massage and obtained satisfactory therapeutic result. A report follows.

  4. The barrier effect of conflict with superiors in the relationship between employee empowerment and organizational commitment

    NARCIS (Netherlands)

    Janssen, O.

    2004-01-01

    The author proposes the idea that conflict with superiors has a barrier effect in the positive relationship between employee empowerment and organizational commitment. Superiors with higher authority rankings set and pursue organizational goals and values to which employees with lower authority rank

  5. ANTHROPOGENIC COPPER INVENTORIES AND MERCURY PROFILES FROM LAKE SUPERIOR: EVIDENCE FOR MINING IMPACTS

    Science.gov (United States)

    During the past 150 years, the mining indstry discharged more than a billion tons of tailings along Lake Superior shorelines and constructed numerous smelters in the watershed. Given the vast size of Lake Superior, were sediment profiles at locations far offshore impacted by near...

  6. MERCURY IN METAL ORE DEPOSITS: AN UNRECOGNIZED, WIDESPREAD SOURCE TO LAKE SUPERIOR SEDIMENTS, CONTRIBUTION #1072

    Science.gov (United States)

    Mining operations have worked the rich mineral resources of the Lake Superior Basin for over 150 years, leaving industrially impacted regions with tailing piles and smelters. In Lake Superior sediments, mercury and copper inventories increase towards shorelines and are highly cor...

  7. Superior Temporal Activation as a Function of Linguistic Knowledge: Insights from Deaf Native Signers Who Speechread

    Science.gov (United States)

    Capek, Cheryl M.; Woll, Bencie; MacSweeney, Mairead; Waters, Dafydd; McGuire, Philip K.; David, Anthony S.; Brammer, Michael J.; Campbell, Ruth

    2010-01-01

    Studies of spoken and signed language processing reliably show involvement of the posterior superior temporal cortex. This region is also reliably activated by observation of meaningless oral and manual actions. In this study we directly compared the extent to which activation in posterior superior temporal cortex is modulated by linguistic…

  8. The barrier effect of conflict with superiors in the relationship between employee empowerment and organizational commitment

    NARCIS (Netherlands)

    Janssen, O.

    The author proposes the idea that conflict with superiors has a barrier effect in the positive relationship between employee empowerment and organizational commitment. Superiors with higher authority rankings set and pursue organizational goals and values to which employees with lower authority

  9. The barrier effect of conflict with superiors in the relationship between employee empowerment and organizational commitment

    NARCIS (Netherlands)

    Janssen, O.

    2004-01-01

    The author proposes the idea that conflict with superiors has a barrier effect in the positive relationship between employee empowerment and organizational commitment. Superiors with higher authority rankings set and pursue organizational goals and values to which employees with lower authority rank

  10. Frequency of the superior rectus muscle overaction/contracture syndrome in unilateral fourth nerve palsy.

    Science.gov (United States)

    Molinari, Andrea; Ugrin, Maria Cristina

    2009-12-01

    Superior oblique palsy is accompanied in most cases by overaction of the muscle's ipsilateral antagonist, the inferior oblique muscle. Overaction and contracture of the ipsilateral superior rectus muscle in patients with unilateral fourth (trochlear) nerve palsy is seldom discussed in the literature. The purpose of this study is to evaluate the frequency of superior rectus muscle overaction/contracture syndrome in patients with unilateral trochlear nerve palsy. The records of 198 patients with unilateral trochlear nerve palsy examined by the authors between July 1987 and July 2008 were reviewed retrospectively. All patients underwent complete eye examination with measurement of the deviation in the 9 positions of gaze and with the head tilted to both sides in all cooperative patients. Selection criteria for superior rectus muscle overaction/contracture syndrome in these patients were as follows: vertical deviation of 15(Delta) or larger in primary position, equal or larger hypertropia with the ipsilateral forced tilt test than with the eyes looking straight ahead, more than 5(Delta) hypertropia of the affected eye in horizontal gaze to the same side, hypertropia in all upgazes, and overaction of the contralateral superior oblique muscle. Of 198 patients, 33 (16.6%) met the selection criteria for superior rectus muscle overaction/contracture syndrome. Superior rectus muscle overaction/contracture syndrome frequently occurs in unilateral superior oblique palsy.

  11. 33 CFR 117.661 - Duluth Ship Canal (Duluth-Superior Harbor).

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Duluth Ship Canal (Duluth-Superior Harbor). 117.661 Section 117.661 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Minnesota § 117.661 Duluth Ship Canal (Duluth-Superior Harbor). The draw...

  12. MERCURY IN METAL ORE DEPOSITS: AN UNRECOGNIZED, WIDESPREAD SOURCE TO LAKE SUPERIOR SEDIMENTS, CONTRIBUTION #1072

    Science.gov (United States)

    Mining operations have worked the rich mineral resources of the Lake Superior Basin for over 150 years, leaving industrially impacted regions with tailing piles and smelters. In Lake Superior sediments, mercury and copper inventories increase towards shorelines and are highly cor...

  13. 77 FR 45490 - Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN

    Science.gov (United States)

    2012-08-01

    ... [Docket Number USCG-2012-0491] RIN 1625-AA00 Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN..., Duluth, MN. This safety zone is precautionary to protect recreational vessels and marine traffic from any... Superior, Duluth, MN. This safety zone will be in effect and enforced 24 hours a day from on or around July...

  14. 77 FR 37321 - Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN

    Science.gov (United States)

    2012-06-21

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN..., Duluth, MN. This safety zone is precautionary to protect recreational vessels and marine traffic from any... Brighton Beach, up to approximately 4 miles offshore on Lake Superior, Duluth, MN. This safety zone will be...

  15. Superior thyroid artery origin in Caucasian Greeks: A new classification proposal and review of the literature.

    Science.gov (United States)

    Natsis, Konstantinos; Raikos, Athanasios; Foundos, Ioannis; Noussios, George; Lazaridis, Nikolaos; Njau, Samouel N

    2011-09-01

    Studies on the origin of the superior thyroid artery, define that it could originate either from the external carotid artery, (at the level of common carotid bifurcation), or from the common carotid artery. However, there is a classical anatomic knowledge that the superior thyroid artery is a branch of the external carotid artery. Variability in the anatomy of the superior thyroid artery was studied on 100 carotids. Moreover, a review about the origin of superior thyroid artery between recent and previous cadaveric, autopsy, and angiographic studies, on adults and fetuses, was carried out. The superior thyroid artery originated from the external carotid artery in 39% and at the level of carotid bifurcation and common carotid artery in 61% of cases. The anterior branches of the external carotid artery were separate in 76% of cases, while common trunks between the arteries were found in 24% of the specimens. A new classification proposal on the origin of the superior thyroid artery is also suggested. In this study, the origin of superior thyroid artery is considered at the level of the carotid bifurcation and not from the external carotid artery as stated in many classical anatomy textbooks. This has a great impact on the terminology when referring to the anterior branches of the external carotid artery, which could be termed as anterior branches of the cervical carotid artery. Head and neck surgeons must be familiar with anatomical variations of the superior thyroid artery in order to achieve a better surgical outcome.

  16. A new Nitinol stent for use in superior vena cava syndrome

    DEFF Research Database (Denmark)

    Andersen, Poul Erik; Midtgaard, Annette; Brenøe, Anne-Sofie;

    2015-01-01

    AIM: The aim of the study was to assess the early clinical experience with the Zilver Vena stent in treating patients with malignant superior vena cava syndrome. METHODS: Demographic, procedural, and follow-up data of 12 patients (seven women; mean age 69 years) treated for superior vena cava syn...

  17. Accessory belly of piriformis, as a cause of superior gluteal neurovascular entrapment

    Directory of Open Access Journals (Sweden)

    Rimple Bansal

    2013-06-01

    Full Text Available During routine dissection on 50 years old male cadaver, an accessory belly of piriformis was observed. This accessory belly was superior and parallel to the main piriformis muscle. This was associated with emergence of superior gluteal nerve and superior gluteal artery between the two bellies. Piriformis muscle and its relation to sciatic nerve has been suggested as a cause of piriformis syndrome. But interestingly in the present case, superior gluteal nerve was interposed between two bellies that may help the clinicians to establish a rare yet important cause of piriformis syndrome and a rare cause of undiagnosed chronic pain in gluteal region. As superior gluteal artery was also interposed, so this rare variation holds interest to surgeons especially in isolated buttock claudication despite otherwise normal vascular investigations. [Int J Res Med Sci 2013; 1(3.000: 296-298

  18. Partial closure of right superior orbital fissure with narrow optic foramen

    Directory of Open Access Journals (Sweden)

    Desai SD

    2010-11-01

    Full Text Available Superior orbital fissure is situated between the greater and lesser wings of sphenoid, with the optic strut at its superomedial margin. It lies between the roof and lateral wall of the orbit. The superior orbital fissure is divided by the common tendinous origin of the recti muscles. Compression of the neurovascular structures due to variations in the superior orbital fissure may result in signs and symptoms due to involvement of cranial nerves III, IV, V1, and VI. We report here a variation of the superior orbital fissure. Superior orbital fissure was partly closed by a thin plate of bone on the right side, and on the same side there was a narrow optic foramen. It is essential to know such variations to understand the underlying cause for the clinical conditions and operate in those areas.

  19. Visual search for emotional expressions: Effect of stimulus set on anger and happiness superiority.

    Science.gov (United States)

    Savage, Ruth A; Becker, Stefanie I; Lipp, Ottmar V

    2016-01-01

    Prior reports of preferential detection of emotional expressions in visual search have yielded inconsistent results, even for face stimuli that avoid obvious expression-related perceptual confounds. The current study investigated inconsistent reports of anger and happiness superiority effects using face stimuli drawn from the same database. Experiment 1 excluded procedural differences as a potential factor, replicating a happiness superiority effect in a procedure that previously yielded an anger superiority effect. Experiments 2a and 2b confirmed that image colour or poser gender did not account for prior inconsistent findings. Experiments 3a and 3b identified stimulus set as the critical variable, revealing happiness or anger superiority effects for two partially overlapping sets of face stimuli. The current results highlight the critical role of stimulus selection for the observation of happiness or anger superiority effects in visual search even for face stimuli that avoid obvious expression related perceptual confounds and are drawn from a single database.

  20. Management Of Abnormal Uterine Bleeding In Perimenarche: Diagnostic Challenges

    OpenAIRE

    Siregar, Muhammad Fidel Ganis

    2016-01-01

    An 18-year-old girl—virgin, Indonesian, Bataknese, Moslem, student—was admitted to the Emergency Department of Haji Adam Malik Hospital, Medan, and presented with prolonged menstruation for the past 3 years, volume 5–6 pads/day, lasting for 3 weeks, dark red, clotting (+), regular menstrual cycles. Vital signs were within normal limits. Physical examination revealed pale inferior conjunctiva palpebral and soft abdomen, with no palpable mass. As the patient was unmarried, speculum and vaginal...